Sample records for proportionate random sample

  1. Women Secondary Principals in Texas 1998 and 2011: Movement toward Equity

    ERIC Educational Resources Information Center

    Marczynski, Jean C.; Gates, Gordon S.

    2013-01-01

    Purpose: The purpose of this paper is to analyze data gathered in 1998 and 2011 from representative samples of women secondary school principals in Texas to identify differences in personal, professional, leadership, and school characteristics. Design/methodology/approach: Two proportionate, random samples were drawn of women secondary principals…

  2. Ground sample data for the Conterminous U.S. Land Cover Characteristics Database

    Treesearch

    Robert Burgan; Colin Hardy; Donald Ohlen; Gene Fosnight; Robert Treder

    1999-01-01

    Ground sample data were collected for a land cover database and raster map that portray 159 vegetation classes at 1 km2 resolution for the conterminous United States. Locations for 3,500 1 km2 ground sample plots were selected randomly across the United States. The number of plots representing each vegetation class was weighted by the proportionate coverage of each...

  3. Do Social Workers Make Better Child Welfare Workers than Non-Social Workers?

    ERIC Educational Resources Information Center

    Perry, Robin E.

    2006-01-01

    Objective: To empirically examine whether the educational background of child welfare workers in Florida impacts on performance evaluations of their work. Method: A proportionate, stratified random sample of supervisor and peer evaluations of child protective investigators and child protective service workers is conducted. ANOVA procedures are…

  4. Cigarette and Nargileh Smoking Practices among School Students in Beirut, Lebanon

    ERIC Educational Resources Information Center

    Tamim, Hala; Al-Sahab, Ban; Akkary, Ghassan; Ghanem, Mary; Tamim, Nada; El Roueiheb, Zana; Kanj, Mayada; Afifi, Rima

    2007-01-01

    Objectives: To determine the prevalence and predictors of smoking nargileh and/or cigarettes among school students in Greater Beirut, Lebanon. Methods: A proportionate random sample of 2443 students from 13 public and private schools was selected and asked to complete self-administered anonymous questionnaires. Results: The prevalence of smoking…

  5. Internal Challenges Affecting Academic Performance of Student-Athletes in Ghanaian Public Universities

    ERIC Educational Resources Information Center

    Apaak, Daniel; Sarpong, Emmanuel Osei

    2015-01-01

    This paper examined internal challenges affecting academic performance of student-athletes in Ghanaian public universities, using a descriptive survey research design. Proportionate random sampling technique was employed to select Three Hundred and Thirty-Two (332) respondents for the study. The instrument used in gathering data for the study was…

  6. Primary Teacher Trainees Preparedness to Teach Science: A Gender Perspective

    ERIC Educational Resources Information Center

    Mutisya, Sammy M.

    2015-01-01

    The purpose of this study was to determine Primary Teacher Education (PTE) Trainees' perceptions regarding their preparedness to teach science in primary schools. A descriptive survey research design was used and stratified proportionate random sampling techniques used to select 177 males and 172 females. The study found out that more male trainee…

  7. Assessing Students' Metacognitive Awareness of Learning Strategies among Secondary School Students in Edo State, Nigeria

    ERIC Educational Resources Information Center

    Okoza, Jolly; Aluede, Oyaziwo; Owens-Sogolo, Osasere

    2013-01-01

    This study examined metacognitive awareness of learning strategies among Secondary School Students in Edo State, Nigeria. The study was an exploratory one, which utilized descriptive statistics. A total number of 1200 students drawn through multistage proportionate random sampling technique participated in the study. The study found that secondary…

  8. Conflict Resolution Strategies in Non-Government Secondary Schools in Benue State, Nigeria

    ERIC Educational Resources Information Center

    Oboegbulem, Angie; Alfa, Idoko Alphonusu

    2013-01-01

    This study investigated perceived CRSs (conflict resolution strategies) for the resolution of conflicts in non-government secondary schools in Benue State, Nigeria. Three research questions and three hypotheses guided this study. Proportionate stratified random sampling technique was used in drawing 15% of the population which gave a total of 500…

  9. Marital and Procreative Projections of Rural Louisiana Youth: A Historical Comparison.

    ERIC Educational Resources Information Center

    Smith, Kevin B.; Ohlendorf, George W.

    Changes in marital and procreative projections among rural Louisiana high school youth between 1968 and 1972 were examined. In 1968 a proportionate, stratified, random cluster sampling technique was employed to secure data on seniors from 13 white and 7 black high schools. In 1972 public school integration and the establishment of private schools…

  10. Social-Economic Factors, Student Factors, Student Academic Goals and Performance of Students in Institutions of Higher Learning in Uganda

    ERIC Educational Resources Information Center

    Ngoma, Muhammed; Ntale, Peter Dithan; Abaho, Earnest

    2017-01-01

    This article evaluates the relationship between social-economic factors, students' factors, student academic goals and performance of students. The study adopts a cross-sectional survey, with largely quantitative approaches. A sample of 950 students was randomly and proportionately drawn from undergraduates in four institutions of higher learning.…

  11. School Types, Facilities and Academic Performance of Students in Senior Secondary Schools in Ondo State, Nigeria

    ERIC Educational Resources Information Center

    Alimi, Olatunji Sabitu; Ehinola, Gabriel Babatunde; Alabi, Festus Oluwole

    2012-01-01

    The study investigated the influence of school types and facilities on students' academic performance in Ondo State. It was designed to find out whether facilities and students' academic performance are related in private and public secondary schools respectively. Descriptive survey design was used. Proportionate random sampling technique was used…

  12. The Effect of Entrepreneurship Education on Entrepreneurial Intention Mediated by Motivation and Attitude among Management Students, State University of Malang, Indonesia

    ERIC Educational Resources Information Center

    Mahendra, Angga Martha; Djatmika, Ery Tri; Hermawan, Agus

    2017-01-01

    This research investigates the effect of entrepreneurship education on entrepreneurial intention among college students enrolling in the Department of Management, Faculty of Economics, State University of Malang. The research employed descriptive correlational design, and a number of 230 students are taken proportionate randomly as sample from 540…

  13. Relationship between Staff-Reported Culture Change and Occupancy Rate and Organizational Commitment among Nursing Homes in South Korea

    ERIC Educational Resources Information Center

    Lee, Minhong; Choi, Jae-Sung; Lim, Jinseop; Kim, Young Sun

    2013-01-01

    Purpose: This study aims to examine culture change in nursing homes in South Korea and to identify the outcomes of culture change implementation. Design and Methods: Data were taken from survey responses from 223 top- or mid-level staff among nursing homes in South Korea that were selected through a proportionate random-stratified sampling method…

  14. A Comparative Study of Language Instructional Delivery System between Nursery Schools in Rural and Urban Areas in Osun State

    ERIC Educational Resources Information Center

    Odejobi, Cecilia Omobola

    2014-01-01

    The study compared the language instructional delivery system between the nursery schools in rural and urban areas in Osun state. The population consisted of all the nursery school teachers in Osun state. Proportionate random sampling was used to prune down the population. In all 130 nursery school teachers, 68 in urban areas and 62 in rural areas…

  15. Facebook and Twitter, communication and shelter, and the 2011 Tuscaloosa tornado.

    PubMed

    Stokes, Courtney; Senkbeil, Jason C

    2017-01-01

    This paper represents one of the first attempts to analyse the many ways in which Facebook and Twitter were used during a tornado disaster. Comparisons between five randomly selected campus samples and a city of Tuscaloosa, Alabama, sample revealed that campus samples used Facebook and Twitter significantly more both before and after the tornado, but Facebook usage was not significantly different after the event. Furthermore, differences in social media usage and other forms of communication before the tornado were found for age, education, and years lived in Tuscaloosa. Generally, age and education were inversely proportionate to social media usage. Influences on shelter-seeking actions varied between social media users and three random samples of non-social media users; however, it appears that social media respondents were likely to be using a smartphone simultaneously to access warning polygon information, to receive text message alerts, and to listen or respond to environmental cues. © 2017 The Author(s). Disasters © Overseas Development Institute, 2017.

  16. Psychiatric disorders and their correlates among young adult MDMA users in Ohio.

    PubMed

    Falck, Russel S; Carlson, Robert G; Wang, Jichuan; Siegal, Harvey A

    2006-03-01

    This study describes the lifetime prevalence, correlates, and age of onset of selected psychiatric disorders among a community sample of MDMA users (n = 402), aged 18 to 30, in Ohio. Participants responded to interviewer-administered questionnaires, including sections of the computerized Diagnostic Interview Schedule for DSM-IV. Fifty-five percent of the sample had at least one lifetime disorder, with major depression (35.3%) and antisocial personality disorder (ASPD) (25.4%) the most common. Proportionately more women were diagnosed with depression, generalized anxiety disorder, and posttraumatic stress disorder (PTSD), while proportionately more men were diagnosed with ASPD. Proportionately more non-White participants had attention deficit/hyperactivity disorder (AD/HD). Higher levels of education were associated with proportionately less PTSD, ASPD, and AD/HD. Higher frequencies of MDMA use were associated with proportionately more ASPD and AD/HD. Comparing the age of first MDMA use with the age of onset for selected psychiatric disorders revealed that for most participants disorders preceded use. Multivariate analysis revealed participants with more than a high school education were less likely to have experienced a lifetime disorder, while those who had used MDMA more than 50 times were more likely. Variations in the prevalence of psychiatric disorders have practical implications for drug abuse prevention and treatment programs.

  17. The impact of financial incentives on participants' food purchasing patterns in a supermarket-based randomized controlled trial.

    PubMed

    Olstad, Dana Lee; Crawford, David A; Abbott, Gavin; McNaughton, Sarah A; Le, Ha Nd; Ni Mhurchu, Cliona; Pollard, Christina; Ball, Kylie

    2017-08-25

    The impacts of supermarket-based nutrition promotion interventions might be overestimated if participants shift their proportionate food purchasing away from their usual stores. This study quantified whether participants who received price discounts on fruits and vegetables (FV) in the Supermarket Healthy Eating for Life (SHELf) randomized controlled trial (RCT) shifted their FV purchasing into study supermarkets during the intervention period. Participants were 642 females randomly assigned to a 1) skill-building (n = 160), 2) price reduction (n = 161), 3) combined skill-building and price reduction (n = 160), or 4) control (n = 161) group. Participants self-reported the proportion of FV purchased in study supermarkets at baseline, 3- and 6-months post-intervention. Fisher's exact and χ 2 tests assessed differences among groups in the proportion of FV purchased in study supermarkets at each time point. Multinomial logistic regression assessed differences among groups in the change in proportionate FV purchasing over time. Post-intervention, 49% of participants purchased ≥50% of their FV in study supermarkets. Compared to all other groups, the price reduction group was approximately twice as likely (RRR: 1.8-2.2) to have increased proportionate purchasing of FV in study supermarkets from baseline to post-intervention (p< 0.05). Participants who received price reductions on FV were approximately twice as likely to shift their FV purchasing from other stores into study supermarkets during the intervention period. Unless food purchasing data are available for all sources, differential changes in purchasing patterns can make it difficult to discern the true impacts of nutrition interventions. The SHELf trial is registered with Current Controlled Trials Registration ISRCTN39432901, Registered 30 June 2010, Retrospectively registered ( http://www.isrctn.com/ISRCTN39432901 ).

  18. An epidemiological study of prevalence and comorbidity of obsessive compulsive disorder symptoms (SOCD) and stress in Pakistani Adults.

    PubMed

    Ashraf, Farzana; Malik, Sadia; Arif, Amna

    2017-01-01

    To investigate the prevalence and comorbidity of subclinical obsessive compulsive disorder (SOCD) symptoms and stress across gender, marital and employment statuses. A cross-sectional research was conducted from December, 2016 to March 2017 at two universities of cosmopolitan city Lahore. Two self-report scales measuring SOCD symptoms and stress were used to collect data from 377 adults selected through simple random sampling technique, proportionately distributed across gender, marital and employment status. From the total sample, 52% reported low level of stress and 48% faced high level of stress. Significant differences in prevalence were observed across marital and employment statuses whereas for men and women, it was observed same (24%). Comorbidity of high level of SOCD symptoms and high level of stress was seen 34%. Significant prevalence and comorbidity exists between SOCD symptoms and stress and more studies addressing diverse population are needed.

  19. ELECTROFISHING EFFORT REQUIREMENTS FOR ASSESSING SPECIES RICHNESS AND BIOTIC INTEGRITY IN WESTERN OREGON STREAMS

    EPA Science Inventory

    We empirically examined the sampling effort required to adequately represent species richness and proportionate abundance when backpack electrofishing western Oregon streams. When sampling, we separately recorded data for each habitat unit. In data analyses, we repositioned each...

  20. The need of adequate information to achieve total compliance of mass drug administration in Pekalongan

    NASA Astrophysics Data System (ADS)

    Ginandjar, Praba; Saraswati, Lintang Dian; Taufik, Opik; Nurjazuli; Widjanarko, Bagoes

    2017-02-01

    World Health Organization (WHO) initiated The Global Program to Eliminate Lymphatic Filariasis (LF) through mass drug administration (MDA). Pekalongan started MDA in 2011. Yet the LF prevalence in 2015 remained exceed the threshold (1%). This study aimed to describe the inhibiting factors related to the compliance of MDA in community level. This was a rapid survey with cross sectional approach. A two-stages random sampling was used in this study. In the first stage, 25 clusters were randomly selected from 27 villages with proportionate to population size (PPS) methods (C-Survey). In the second stage, 10 subjects were randomly selected from each cluster. Subject consisted of 250 respondents from 25 selected clusters. Variables consisted of MDA coverage, practice of taking medication during MDA, enabling and inhibiting factors to MDA in community level. The results showed most respondents had poor knowledge on filariasis, which influence awareness of the disease. Health-illness perception, did not receive the drugs, lactation, side effect, and size of the drugs were dominant factors of non-compliance to MDA. MDA information and community empowerment were needed to improve MDA coverage. Further study to explore the appropriate model of socialization will support the success of MDA program

  1. Assessing the sustainable construction of large construction companies in Malaysia

    NASA Astrophysics Data System (ADS)

    Adewale, Bamgbade Jibril; Mohammed, Kamaruddeen Ahmed; Nasrun, Mohd Nawi Mohd

    2016-08-01

    Considering the increasing concerns for the consideration of sustainability issues in construction project delivery within the construction industry, this paper assesses the extent of sustainable construction among Malaysian large contractors, in order to ascertain the level of the industry's impacts on both the environment and the society. Sustainable construction explains the construction industry's responsibility to efficiently utilise the finite resources while also reducing construction impacts on both humans and the environment throughout the phases of construction. This study used proportionate stratified random sampling to conduct a field study with a sample of 172 contractors out of the 708 administered questionnaires. Data were collected from large contractors in the eleven states of peninsular Malaysia. Using the five-level rating scale (which include: 1= Very Low; 2= Low; 3= Moderate; 4= High; 5= Very High) to describe the level of sustainable construction of Malaysian contractors based on previous studies, statistical analysis reveals that environmental, social and economic sustainability of Malaysian large contractors are high.

  2. The quality of care in occupational therapy: an assessment of selected Michigan hospitals.

    PubMed

    Kirchman, M M

    1979-07-01

    In this study, a methodology was developed and tested for assessing the quality of care in occupational therapy between educational and noneducational clinical settings, as measured by process and outcome. An instrument was constructed for an external audit of the hospital record. Standards drafted by the investigator were established as normative by a panel of experts for use in judging the programs. Hospital records of 84 patients with residual hemiparesis or hemiplegia in three noneducational settings and of 100 patients with similar diagnoses in two educational clinical settings from selected Michigan facilities were chosen by proportionate stratified random sampling. The process study showed that occupational therapy was of significantly higher quality in the educational settings. The outcome study did not show significant differences between types of settings. Implications for education and practice are discussed.

  3. Air Force Journal of Logistics. Volume 24, Number 3, Fall 2000

    DTIC Science & Technology

    2000-01-01

    senior officers environment. 49 should hold key positions. The joint practice of assigning an In The Argument Culture, Deborah Tannen suggests Americans...Action Division, Directorate of Plans and Integration, Deputy 44. Deborah Tannen , The Argument Culture, New York: Random House, Chief of Staff for...staff.4 " Proportionate representation would Americans must find the opposing view. Tannen says Americans * establish multinationalism as the norm and

  4. 7 CFR 1435.311 - Proportionate shares for sugarcane producers.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Flexible Marketing Allotments For Sugar § 1435.311 Proportionate shares for sugarcane producers. (a... sugarcane farms. (b) CCC will determine whether Louisiana sugar production, in the absence of proportionate...

  5. 7 CFR 1435.311 - Proportionate shares for sugarcane producers.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Flexible Marketing Allotments For Sugar § 1435.311 Proportionate shares for sugarcane producers. (a... sugarcane farms. (b) CCC will determine whether Louisiana sugar production, in the absence of proportionate...

  6. 7 CFR 1435.311 - Proportionate shares for sugarcane producers.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Flexible Marketing Allotments For Sugar § 1435.311 Proportionate shares for sugarcane producers. (a... sugarcane farms. (b) CCC will determine whether Louisiana sugar production, in the absence of proportionate...

  7. 7 CFR 1435.311 - Proportionate shares for sugarcane producers.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Flexible Marketing Allotments For Sugar § 1435.311 Proportionate shares for sugarcane producers. (a... sugarcane farms. (b) CCC will determine whether Louisiana sugar production, in the absence of proportionate...

  8. 7 CFR 1435.311 - Proportionate shares for sugarcane producers.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Flexible Marketing Allotments For Sugar § 1435.311 Proportionate shares for sugarcane producers. (a... sugarcane farms. (b) CCC will determine whether Louisiana sugar production, in the absence of proportionate...

  9. [Factors related to awareness on tobacco advertisement and promotion among adults in six cities in China].

    PubMed

    Yang, Yan; Wu, Xi; Li, Qiang; Jiao, Shu-fang; Li, Xun; Li, Xin-jian; Zhu, Guo-ping; Du, Lin; Zhao, Jian-hua; Jiang, Yuan; Feng, Guo-ze

    2009-04-01

    To know the situation of tobacco advertisement, promotions and related factors in six cities in China. 4815 adults (above 18 years), selected form Beijing, Shanghai, Shenyang, Changsha, Guangzhou and Yinchuan through probability proportionate sampling and simple random sampling, were investigated through questionnaires. The most commonly reported channels that smokers noticed tobacco advertisements were billboards (35.6%) and television (34.4%). The most commonly reported tobacco promotional activities that were noticed by smokers were free gifts when buying cigarettes (23.1%) and free samples of cigarettes (13.9%). Smokers in Changsha were more likely to report noticing tobacco advertisement on billboards (chi2 = 562.474, P < 0.00 1), and on television (chi2 = 265.570, P < 0.001). Smokers in Changsha (chi2 = 58.314, P < 0.001) were more likely to notice tobacco related news and games. A logistic regression analysis showed that the living and education level were related to awareness of tobacco advertisement and promotion. It was universal to see tobacco advertisement and promotions in cities in China but the laws and regulations about tobacco-control were not uniformly executed in different cities. It is necessary to perfect and uniform related laws and regulations.

  10. The relationships between sixteen perfluorinated compound concentrations in blood serum and food, and other parameters, in the general population of South Korea with proportionate stratified sampling method.

    PubMed

    Kim, Hee-Young; Kim, Seung-Kyu; Kang, Dong-Mug; Hwang, Yong-Sik; Oh, Jeong-Eun

    2014-02-01

    Serum samples were collected from volunteers of various ages and both genders using a proportionate stratified sampling method, to assess the exposure of the general population in Busan, South Korea to perfluorinated compounds (PFCs). 16 PFCs were investigated in serum samples from 306 adults (124 males and 182 females) and one day composite diet samples (breakfast, lunch, and dinner) from 20 of the serum donors, to investigate the relationship between food and serum PFC concentrations. Perfluorooctanoic acid and perfluorooctanesulfonic acid were the dominant PFCs in the serum samples, with mean concentrations of 8.4 and 13 ng/mL, respectively. Perfluorotridecanoic acid was the dominant PFC in the composite food samples, ranging from

  11. Precipitation and Latent Heating Distributions from Satellite Passive Microwave Radiometry. Part 1; Improved Method and Uncertainties

    NASA Technical Reports Server (NTRS)

    Olson, William S.; Kummerow, Christian D.; Yang, Song; Petty, Grant W.; Tao, Wei-Kuo; Bell, Thomas L.; Braun, Scott A.; Wang, Yansen; Lang, Stephen E.; Johnson, Daniel E.; hide

    2006-01-01

    A revised Bayesian algorithm for estimating surface rain rate, convective rain proportion, and latent heating profiles from satellite-borne passive microwave radiometer observations over ocean backgrounds is described. The algorithm searches a large database of cloud-radiative model simulations to find cloud profiles that are radiatively consistent with a given set of microwave radiance measurements. The properties of these radiatively consistent profiles are then composited to obtain best estimates of the observed properties. The revised algorithm is supported by an expanded and more physically consistent database of cloud-radiative model simulations. The algorithm also features a better quantification of the convective and nonconvective contributions to total rainfall, a new geographic database, and an improved representation of background radiances in rain-free regions. Bias and random error estimates are derived from applications of the algorithm to synthetic radiance data, based upon a subset of cloud-resolving model simulations, and from the Bayesian formulation itself. Synthetic rain-rate and latent heating estimates exhibit a trend of high (low) bias for low (high) retrieved values. The Bayesian estimates of random error are propagated to represent errors at coarser time and space resolutions, based upon applications of the algorithm to TRMM Microwave Imager (TMI) data. Errors in TMI instantaneous rain-rate estimates at 0.5 -resolution range from approximately 50% at 1 mm/h to 20% at 14 mm/h. Errors in collocated spaceborne radar rain-rate estimates are roughly 50%-80% of the TMI errors at this resolution. The estimated algorithm random error in TMI rain rates at monthly, 2.5deg resolution is relatively small (less than 6% at 5 mm day.1) in comparison with the random error resulting from infrequent satellite temporal sampling (8%-35% at the same rain rate). Percentage errors resulting from sampling decrease with increasing rain rate, and sampling errors in latent heating rates follow the same trend. Averaging over 3 months reduces sampling errors in rain rates to 6%-15% at 5 mm day.1, with proportionate reductions in latent heating sampling errors.

  12. Knowledge and use of information and communication technology by health sciences students of the University of Ghana.

    PubMed

    Dery, Samuel; Vroom, Frances da-Costa; Godi, Anthony; Afagbedzi, Seth; Dwomoh, Duah

    2016-09-01

    Studies have shown that ICT adoption contributes to productivity and economic growth. It is therefore important that health workers have knowledge in ICT to ensure adoption and uptake of ICT tools to enable efficient health delivery. To determine the knowledge and use of ICT among students of the College of Health Sciences at the University of Ghana. This was a cross-sectional study conducted among students in all the five Schools of the College of Health Sciences at the University of Ghana. A total of 773 students were sampled from the Schools. Sampling proportionate to size was then used to determine the sample sizes required for each school, academic programme and level of programme. Simple random sampling was subsequently used to select students from each stratum. Computer knowledge was high among students at almost 99%. About 83% owned computers (p < 0.001) and self-rated computer knowledge was also 87 % (p <0.001). Usage was mostly for studying at 93% (p< 0.001). This study shows students have adequate knowledge and use of computers. It brings about an opportunity to introduce ICT in healthcare delivery to them. This will ensure their adequate preparedness to embrace new ways of delivering care to improve service delivery. Africa Build Project, Grant Number: FP7-266474.

  13. 34 CFR Appendix B to Part 300 - Proportionate Share Calculation

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 2 2014-07-01 2013-07-01 true Proportionate Share Calculation B Appendix B to Part 300... CHILDREN WITH DISABILITIES Pt. 300, App. B Appendix B to Part 300—Proportionate Share Calculation Each LEA... special education and related services under Part B, as compared with the total number of eligible...

  14. Invasive plants have scale-dependent effects on diversity by altering species-area relationships.

    PubMed

    Powell, Kristin I; Chase, Jonathan M; Knight, Tiffany M

    2013-01-18

    Although invasive plant species often reduce diversity, they rarely cause plant extinctions. We surveyed paired invaded and uninvaded plant communities from three biomes. We reconcile the discrepancy in diversity loss from invaders by showing that invaded communities have lower local richness but steeper species accumulation with area than that of uninvaded communities, leading to proportionately fewer species loss at broader spatial scales. We show that invaders drive scale-dependent biodiversity loss through strong neutral sampling effects on the number of individuals in a community. We also show that nonneutral species extirpations are due to a proportionately larger effect of invaders on common species, suggesting that rare species are buffered against extinction. Our study provides a synthetic perspective on the threat of invasions to biodiversity loss across spatial scales.

  15. 26 CFR 1.1561-2 - Special rules for allocating reductions of certain section 1561(a) tax-benefit items.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... members are required to apportion the amount of the additional tax using the proportionate method... proportionate method, the additional tax is allocated to each component member in the same proportion as the... steps for applying the proportionate method of allocation are as follows: (1) Step 1. The regular tax...

  16. Birth Order, Family Configuration and Personal Problems.

    DTIC Science & Technology

    1973-09-01

    Significant birth order effects were found in a sample of applicants to West Point with respect to the frequency with which they reported having...the U.S. Military Academy in greater proportionate numbers than others, there is no evidence that they perform better than those from other birth - order groups. (Author)

  17. Curriculum Review Evaluation on Entrepreneurial Education in Cross River State Higher Institutions

    ERIC Educational Resources Information Center

    Ambekeh, Udida Lucy

    2013-01-01

    This study investigated curriculum organization and delivery towards functional entrepreneurial education transformation of students in Higher Institutions in Cross River State -- Nigeria. To guide the conduct of this study, two research questions and one hypothesis were formulated. Proportionate stratified sampling technique was used in the…

  18. Violence and social capital in post-conflict Guatemala.

    PubMed

    Dinesen, Cecilie; Ronsbo, Henrik; Juárez, Carla; González, Mariano; Estrada Méndez, Miguel Ángel; Modvig, Jens

    2013-09-01

    Violence in post-conflict Guatemala has serious public health consequences for the population. The objective of this study was to assess the relationship between violence and social capital. Data from a cross-sectional victimization survey conducted in 2008 - 2010 in Guatemala were analyzed. Two-stage proportionate sampling was used in the survey. Households (n = 1 300) were randomly sampled within a random sample of communities (n = 118) in five administrative departments. The survey collected information on the six-month violence exposure of 6 335 individuals. Social capital was measured at the household level using the short version of the Adapted Social Capital Tool (SASCAT). The odds ratio for household violence exposure was estimated using multiple logistic regression. Community-level data from the latest national census were included as explanatory factors at the community level. Income, ethnicity, and social capital were included at the household level. Data were analyzed using SPSS 18.0. In total, 2.7% of individuals and 11.7% of households had been exposed to violence within the past six months. The multivariate analysis showed that 1) structural social capital (in this case, the level of participation in social networks and civil society) was a risk factor for violence and 2) cognitive social capital (measured as trust, norms, and sense of belonging) was a protective factor for violence. The opposite direction of the association between violence and structural and cognitive social capital challenges the use of social capital as a unified concept. If this finding is corroborated by other studies, structural and cognitive social capital will have to be treated as two distinctly different concepts.

  19. A Struggle for Dominance: Relational Communication Messages in Television Programming.

    ERIC Educational Resources Information Center

    Barbatsis, Gretchen S.; And Others

    Television's messages about sex role behavior were analyzed by collecting and coding spot samples of the ten top ranked programs in prime viewing time and proportionate numbers of daytime soap operas and Saturday morning children's programs. The content analysis was based on a relational coding system developed to assess interpersonal…

  20. POPULATION-BASED EXPOSURE MEASUREMENTS IN ARIZONA: A PHASE FIELD STUDY IN SUPPORT OF THE NATIONAL HUMAN EXPOSURE ASSESSMENT SURVEY

    EPA Science Inventory

    The objectives of this field study are to determine the distributions of total human exposures to multi-media pollutants in the classes of metals, pesticides, and volatile organic compounds (VOCs) by studying a proportionate-based sample of the total population (with a nested des...

  1. Precision-cut tissue chips as an in vitro toxicology system

    PubMed Central

    Catania, J. M.; Pershing, A. M.; Gandolfi, A. J.

    2007-01-01

    Precision-cut tissue slices mimic specific organ toxicity because normal cellular heterogeneity and organ architecture are retained. To optimize the use of the smaller tissues of the mouse and to establish easy assays for tissue viability, a tissue chip based system was used to generate large numbers of samples from a single organ. Iodoacetamide (IAM), was used as a model toxicant, and assays for intracellular potassium (normalized to DNA content) were used to establish viability and toxicant susceptibility. Thereafter, assays that were more rapid and specific were pursued. Lysates from tissues incubated in 6-carboxyfluorescein fluoresced proportionately to concentrations of IAM, indicating disruption of cellular membranes. Similarly, FURA-2, a probe applied to lysates to measure calcium levels, fluoresced proportionately to IAM dosage. Monobromobimane, a fluorescent sulfhydryl probe, displayed a decrease in fluorescent intensity at higher IAM challenge; a finding confirmed with an absorbance assay with Ellman’s reagent. Importantly, the number of samples per organ/mouse was increased at least 3-fold and a significant time reduction per analysis was realized. PMID:17376647

  2. Household Expenditure on Tobacco Consumption in a Poverty-Stricken Rural District in Sri Lanka.

    PubMed

    Perera, K Manuja N; Guruge, G N Duminda; Jayawardana, Pushpa L

    2017-03-01

    Tobacco is a determinant of poverty and a barrier for development. Monaragala, a rural, agricultural district, reports the highest poverty-related indicators in southern Sri Lanka. A cross-sectional study was used to describe the household expenditure on tobacco and its association with food- and education-related expenditures at household level. This study used a 4-stage cluster sampling method to recruit a representative sample of 1160 households. Response rate was 98.6%. Median monthly household income was LKR 20 000 (interquartile range [IQR] = LKR 12 000-30 000). The median monthly expenditure on tobacco was LKR 1000 (IQR = LKR 400-2000) with the highest spending tertile reporting a median of LKR 2700 (IQR = LKR 2000-3600).The proportionate expenditure from the monthly income ranged from 0.0% to 50% with a median of 5.0% (IQR = 2.0-10.0) and a mean of 7.4% (7.6). The poorest reported the highest mean proportionate expenditure (9.8%, SD = 10) from the household income. Household expenditure on tobacco negatively associated with expenditure on education.

  3. On the origin of size-dependent and size-independent crystal growth: Influence of advection and diffusion

    USGS Publications Warehouse

    Kile, D.E.; Eberl, D.D.

    2003-01-01

    Crystal growth experiments were conducted using potassium alum and calcite crystals in aqueous solution under both non-stirred and stirred conditions to elucidate the mechanism for size-dependent (proportionate) and size-independent (constant) crystal growth. Growth by these two laws can be distinguished from each other because the relative size difference among crystals is maintained during proportionate growth, leading to a constant crystal size variance (??2) for a crystal size distribution (CSD) as the mean size increases. The absolute size difference among crystals is maintained during constant growth, resulting in a decrease in size variance. Results of these experiments show that for centimeter-sized alum crystals, proportionate growth occurs in stirred systems, whereas constant growth occurs in non-stirred systems. Accordingly, the mechanism for proportionate growth is hypothesized to be related to the supply of reactants to the crystal surface by advection, whereas constant growth is related to supply by diffusion. Paradoxically, micrometer-sized calcite crystals showed proportionate growth both in stirred and in non-stirred systems. Such growth presumably results from the effects of convection and Brownian motion, which promote an advective environment and hence proportionate growth for minute crystals in non-stirred systems, thereby indicating the importance of solution velocity relative to crystal size. Calcite crystals grown in gels, where fluid motion was minimized, showed evidence for constant, diffusion-controlled growth. Additional investigations of CSDs of naturally occurring crystals indicate that proportionate growth is by far the most common growth law, thereby suggesting that advection, rather than diffusion, is the dominant process for supplying reactants to crystal surfaces.

  4. Openness to experience, work experience and patient safety.

    PubMed

    Chang, Hao-Yuan; Friesner, Daniel; Lee, I-Chen; Chu, Tsung-Lan; Chen, Hui-Ling; Wu, Wan-Er; Teng, Ching-I

    2016-11-01

    The purpose of this study is to examine how the interaction between nurse openness and work experience is related to patient safety. No study has yet examined the interactions between these, and how openness and work experience jointly impact patient safety. This study adopts a cross-sectional design, using self-reported work experience, perceived time pressure and measures of patient safety, and was conducted in a major medical centre. The sample consisted of 421 full-time nurses from all available units in the centre. Proportionate random sampling was used. Patient safety was measured using the self-reported frequency of common adverse events. Openness was self-rated using items identified in the relevant literature. Nurse openness is positively related to the patient safety construct (B = 0.08, P = 0.03). Moreover, work experience reduces the relation between openness and patient safety (B = -0.12, P < 0.01). The relationship between openness, work experience and patient safety suggests a new means of improving patient care in a health system setting. Nurse managers may enhance patient safety by assessing nurse openness and assigning highly open nurses to duties that make maximum use of that trait. © 2016 John Wiley & Sons Ltd.

  5. FP-180 Water Motor AFFF Proportioner First Article Procedure and Evaluation

    DTIC Science & Technology

    1989-07-20

    concentrates. The first fluorocarbon-based Aqueous Film Forming Foam ( AFFF ) concentrate fully suitable for use with ocean water was FC -195, which had a...Fil E W Y. . Naval Research Laboratory Washington, DC 20375-500 NRL Memorandum Report 6507 FP-180 Water Motor AFFF Proportioner First Article...NUMBERS PROGRAM :PROJECT TASK WORK UNIT ELEMENT NO NO NO ACCESSION NO 11 TITLE (Include Security Classification) FP-180 Water Motor AFFF Proportioner

  6. Archaeological Salvage Excavations at the L.A. Strickland I Site (22Ts765), Tishomingo County, Mississippi.

    DTIC Science & Technology

    1978-12-01

    were identified to genus and when possible to species. These samples give an indication of the wood types present and their proportionate representation...in the features. Nutshells were sorted by genus and weighed. Seeds which retained their diagnostic characteristics were identified and counted. The...Vitis sp.), l persimmon ( Diospyros viiniana) and 1 round seed misiffng all diagnostic features. Feature 2. The sample from Feature 2 contained 55 grams

  7. 7 CFR 1435.317 - Revisions of allocations and proportionate shares.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Flexible Marketing Allotments For Sugar § 1435.317 Revisions of allocations and proportionate shares. The...

  8. 7 CFR 1435.317 - Revisions of allocations and proportionate shares.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Flexible Marketing Allotments For Sugar § 1435.317 Revisions of allocations and proportionate shares. The...

  9. 7 CFR 1435.317 - Revisions of allocations and proportionate shares.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Flexible Marketing Allotments For Sugar § 1435.317 Revisions of allocations and proportionate shares. The...

  10. 7 CFR 1435.317 - Revisions of allocations and proportionate shares.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Flexible Marketing Allotments For Sugar § 1435.317 Revisions of allocations and proportionate shares. The...

  11. 7 CFR 1435.317 - Revisions of allocations and proportionate shares.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Flexible Marketing Allotments For Sugar § 1435.317 Revisions of allocations and proportionate shares. The...

  12. Are quantitative trait-dependent sampling designs cost-effective for analysis of rare and common variants?

    PubMed

    Yilmaz, Yildiz E; Bull, Shelley B

    2011-11-29

    Use of trait-dependent sampling designs in whole-genome association studies of sequence data can reduce total sequencing costs with modest losses of statistical efficiency. In a quantitative trait (QT) analysis of data from the Genetic Analysis Workshop 17 mini-exome for unrelated individuals in the Asian subpopulation, we investigate alternative designs that sequence only 50% of the entire cohort. In addition to a simple random sampling design, we consider extreme-phenotype designs that are of increasing interest in genetic association analysis of QTs, especially in studies concerned with the detection of rare genetic variants. We also evaluate a novel sampling design in which all individuals have a nonzero probability of being selected into the sample but in which individuals with extreme phenotypes have a proportionately larger probability. We take differential sampling of individuals with informative trait values into account by inverse probability weighting using standard survey methods which thus generalizes to the source population. In replicate 1 data, we applied the designs in association analysis of Q1 with both rare and common variants in the FLT1 gene, based on knowledge of the generating model. Using all 200 replicate data sets, we similarly analyzed Q1 and Q4 (which is known to be free of association with FLT1) to evaluate relative efficiency, type I error, and power. Simulation study results suggest that the QT-dependent selection designs generally yield greater than 50% relative efficiency compared to using the entire cohort, implying cost-effectiveness of 50% sample selection and worthwhile reduction of sequencing costs.

  13. 7 CFR 1435.314 - Temporary transfer of proportionate share due to disasters.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Flexible Marketing Allotments For Sugar § 1435.314 Temporary transfer of proportionate share due to...

  14. 7 CFR 1435.314 - Temporary transfer of proportionate share due to disasters.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Flexible Marketing Allotments For Sugar § 1435.314 Temporary transfer of proportionate share due to...

  15. 7 CFR 1435.314 - Temporary transfer of proportionate share due to disasters.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Flexible Marketing Allotments For Sugar § 1435.314 Temporary transfer of proportionate share due to...

  16. 7 CFR 1435.314 - Temporary transfer of proportionate share due to disasters.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Flexible Marketing Allotments For Sugar § 1435.314 Temporary transfer of proportionate share due to...

  17. 7 CFR 1435.314 - Temporary transfer of proportionate share due to disasters.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Flexible Marketing Allotments For Sugar § 1435.314 Temporary transfer of proportionate share due to...

  18. Avoiding Steric Congestion in Dendrimer Growth through Proportionate Branching. A Twist on da Vinci's Rule of Tree Branching

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yue, Xuyi; Taraban, Marc B.; Hyland, Laura L.

    2012-10-05

    In making defect-free macromolecules, the challenge occurs during chemical synthesis. This challenge is especially pronounced in dendrimer synthesis where exponential growth quickly leads to steric congestion. To overcome this difficulty, proportionate branching in dendrimer growth is proposed. In proportionate branching, both the number and the length of branches increase exponentially but in opposite directions to mimic tree growth. The effectiveness of this strategy is demonstrated through the synthesis of a fluorocarbon dendron containing 243 chemically identical fluorine atoms with a MW of 9082 Da. Monodispersity is confirmed by nuclear magnetic resonance spectroscopy, mass spectrometry, and small-angle X-ray scattering. Moreover, growingmore » different parts proportionately, as nature does, could be a general strategy to achieve defect-free synthesis of macromolecules.« less

  19. Comparing Two Survey Research Approaches: E-Mail and Web-Based Technology versus Traditional Mail.

    ERIC Educational Resources Information Center

    Howes, Colleen M.; Mailloux, Mark R.

    2001-01-01

    Contrasted two survey methodologies: e-mail-Web and traditional mail. Found that: (1) e-mail-Web respondents were proportionately more likely to be male and enrolled in school full-time; (2) more individual question non-response was present for the e-mail-Web sample; and (3) e-mail-Web respondents value different aspects of graduate school. (EV)

  20. A Variable Step-Size Proportionate Affine Projection Algorithm for Identification of Sparse Impulse Response

    NASA Astrophysics Data System (ADS)

    Liu, Ligang; Fukumoto, Masahiro; Saiki, Sachio; Zhang, Shiyong

    2009-12-01

    Proportionate adaptive algorithms have been proposed recently to accelerate convergence for the identification of sparse impulse response. When the excitation signal is colored, especially the speech, the convergence performance of proportionate NLMS algorithms demonstrate slow convergence speed. The proportionate affine projection algorithm (PAPA) is expected to solve this problem by using more information in the input signals. However, its steady-state performance is limited by the constant step-size parameter. In this article we propose a variable step-size PAPA by canceling the a posteriori estimation error. This can result in high convergence speed using a large step size when the identification error is large, and can then considerably decrease the steady-state misalignment using a small step size after the adaptive filter has converged. Simulation results show that the proposed approach can greatly improve the steady-state misalignment without sacrificing the fast convergence of PAPA.

  1. Cross-level inferences of job satisfaction in the prediction of intent to leave.

    DOT National Transportation Integrated Search

    1991-10-01

    An emerging literature has demonstrated that proportionately more dissatisfied employees intend to leave their employing organization while proportionately more satisfied employees intend to remain. The purpose of the present study was to apply crite...

  2. [Prevalence of domestic violence in the city of Durango].

    PubMed

    Alvarado-Zaldívar, G; Salvador-Moysén, J; Estrada-Martínez, S; Terrones-González, A

    1998-01-01

    To characterize and determine the prevalence of the different types of gender-associated violence in the city of Durango, Mexico. With a transversal design, 384 women residents of the city of Durango, either living with or having lived with someone before, were interviewed. The sample was proportionately distributed in 6 city sectors which were randomly chosen and representative of the high middle and low socioeconomic levels. Sixty-four interviews were conducted in each city sector. The questionnaire consisted of 184 closed and 22 open questions, including identification, sociodemographic and reproductive data, as well as specific questions on physical, emotional and sexual violence. Median age of the studied group was 41.5 years, ranging from 12 to 48 years. Prevalence of domestic violence was: sexual 42%; physical 40%; emotional 39%. The problem of violence, in its different forms, is a highly prevalent factor which jeopardizes the welfare of the family nucleus. Higher prevalence values of domestic violence were detected in the presence of factors such as violence antecedents, alcoholism and/or drug consumption by some member of the family.

  3. Severe mental deficiency, proportionate dwarfism, and delayed sexual maturation. A distinct inherited syndrome.

    PubMed

    Cantú, J M; Sánchez-Corona, J; García-Cruz, D; Fragoso, R

    1980-01-01

    Two 46,XY brothers were found to have a previously undescribed syndrome characterized by severe mental deficiency, proportionate dwarfism, and delayed sexual development. A recessive mode of inheritance, either autosomal or X-linked, is assumed.

  4. 7 CFR 1435.315 - Adjustments to proportionate shares.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Flexible Marketing Allotments For Sugar § 1435.315 Adjustments to proportionate shares. Whenever CCC determines that, because of... sufficient to enable state processors to produce sufficient sugar to meet the State's cane sugar allotment...

  5. 7 CFR 1435.315 - Adjustments to proportionate shares.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Flexible Marketing Allotments For Sugar § 1435.315 Adjustments to proportionate shares. Whenever CCC determines that, because of... sufficient to enable state processors to produce sufficient sugar to meet the State's cane sugar allotment...

  6. 7 CFR 1435.315 - Adjustments to proportionate shares.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Flexible Marketing Allotments For Sugar § 1435.315 Adjustments to proportionate shares. Whenever CCC determines that, because of... sufficient to enable state processors to produce sufficient sugar to meet the State's cane sugar allotment...

  7. 7 CFR 1435.315 - Adjustments to proportionate shares.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Flexible Marketing Allotments For Sugar § 1435.315 Adjustments to proportionate shares. Whenever CCC determines that, because of... sufficient to enable state processors to produce sufficient sugar to meet the State's cane sugar allotment...

  8. 7 CFR 1435.315 - Adjustments to proportionate shares.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Flexible Marketing Allotments For Sugar § 1435.315 Adjustments to proportionate shares. Whenever CCC determines that, because of... sufficient to enable state processors to produce sufficient sugar to meet the State's cane sugar allotment...

  9. Primary zone air proportioner

    DOEpatents

    Cleary, Edward N. G.

    1982-10-12

    An air proportioner is provided for a liquid hydrocarbon fueled gas turbine of the type which is convertible to oil gas fuel and to coal gas fuel. The turbine includes a shell for enclosing the turbine, an air duct for venting air in said shell to a gasifier, and a fuel injector for injecting gasified fuel into the turbine. The air proportioner comprises a second air duct for venting air from the air duct for mixing with fuel from the gasifier. The air can be directly injected into the gas combustion basket along with the fuel from the injector or premixed with fuel from the gasifier prior to injection by the fuel injector.

  10. 26 CFR 1.50A-7 - Partnerships.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... such WIN expenses relate, such partner's proportionate interest in the general profits of the... subparagraph, then, on the date of such reduction the employment of such employee shall be deemed terminated with respect to such partner to the extent of the actual reduction in such partner's proportionate...

  11. 26 CFR 1.50A-7 - Partnerships.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... such WIN expenses relate, such partner's proportionate interest in the general profits of the... subparagraph, then, on the date of such reduction the employment of such employee shall be deemed terminated with respect to such partner to the extent of the actual reduction in such partner's proportionate...

  12. Impact of Sense of Coherence on Oral Health among Bus Drivers: A Cross-Sectional Study

    PubMed Central

    Ahmed, Shaik Ijaz; Sudhir, Kudlur Maheswarappa; Reddy, V. Chandra Sekhara; Kumar, R. V. S. Krishna; Srinivasulu, G.; Deepthi, Athuluru

    2018-01-01

    Aim and Objectives: To assess the sense of coherence (SOC) and the impact of SOC on oral hygiene behaviors and oral health status among bus drivers in Nellore district, Andhra Pradesh. Materials and Methods: A descriptive cross-sectional study was conducted during August–September 2017. Cluster random sampling methodology was used for the selection of drivers. Five depots were randomly selected from the list of various Andhra Pradesh State Road Transport Corporation depots in Nellore district. The estimated sample size was proportionately divided among these five depots of Nellore district (n = 120). The SOC-related data were obtained using short version of Antonovsky's SOC scale. Every item was scored on a Likert scale ranging from 1 to 7. The sum of the scores for SOC was 13–91. A high score indicates a strong SOC. Clinical examination was done for recording oral health status using Oral Hygiene Index-simplified (OHI-S), dental caries, periodontal status, and oral mucosal lesions were recorded according to the WHO criteria 1997. Data were entered and analyzed using SPSS ver. 22 (SPSS Inc., Chicago, IL, USA). Results: Majority of the bus drivers who participated in the study had a low SOC (60%). A significant (P < 0.05) positive correlation was observed with age (r = 0.1420), socioeconomic status (r = 0.1467), and visit to dentist (r = 0.1912). A nonsignificant negative correlation was observed with habits (r = −0.0681), OHI-S (r = −0.0772), dental caries (r = −0.0874), Community Periodontal Index (r = −0.0642), loss of attachment (r = −0.0650), and oral mucosal lesions (r = −0.0542). Conclusion: Strong SOC was associated with increase in age, better socioeconomic status, good habits, increased frequency of dental visits, and a good oral health.

  13. 7 CFR 1435.316 - Acreage reports for purposes of proportionate shares.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Flexible Marketing Allotments For Sugar § 1435.316 Acreage reports for purposes of proportionate shares. (a) A report of planted and failed acreage shall be required on farms that produce sugarcane for sugar...

  14. 7 CFR 1435.312 - Establishment of acreage bases under proportionate shares.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Flexible Marketing Allotments For Sugar § 1435.312 Establishment of acreage bases under proportionate... shares as the simple average of the acreage planted and considered planted for harvest for sugar or seed...

  15. 7 CFR 1435.316 - Acreage reports for purposes of proportionate shares.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Flexible Marketing Allotments For Sugar § 1435.316 Acreage reports for purposes of proportionate shares. (a) A report of planted and failed acreage shall be required on farms that produce sugarcane for sugar...

  16. 7 CFR 1435.312 - Establishment of acreage bases under proportionate shares.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Flexible Marketing Allotments For Sugar § 1435.312 Establishment of acreage bases under proportionate... shares as the simple average of the acreage planted and considered planted for harvest for sugar or seed...

  17. 34 CFR Appendix B to Part 300 - Proportionate Share Calculation

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... CHILDREN WITH DISABILITIES Pt. 300, App. B Appendix B to Part 300—Proportionate Share Calculation Each LEA... the parentally-placed private school children with disabilities enrolled in private elementary schools... LEA's subgrant under section 611(f) of the Act for children with disabilities aged 3 through 21. This...

  18. 7 CFR 1435.312 - Establishment of acreage bases under proportionate shares.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Flexible Marketing Allotments For Sugar § 1435.312 Establishment of acreage bases under proportionate... shares as the simple average of the acreage planted and considered planted for harvest for sugar or seed...

  19. 7 CFR 1435.316 - Acreage reports for purposes of proportionate shares.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Flexible Marketing Allotments For Sugar § 1435.316 Acreage reports for purposes of proportionate shares. (a) A report of planted and failed acreage shall be required on farms that produce sugarcane for sugar...

  20. 7 CFR 1435.316 - Acreage reports for purposes of proportionate shares.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Flexible Marketing Allotments For Sugar § 1435.316 Acreage reports for purposes of proportionate shares. (a) A report of planted and failed acreage shall be required on farms that produce sugarcane for sugar...

  1. 7 CFR 1435.316 - Acreage reports for purposes of proportionate shares.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Flexible Marketing Allotments For Sugar § 1435.316 Acreage reports for purposes of proportionate shares. (a) A report of planted and failed acreage shall be required on farms that produce sugarcane for sugar...

  2. 7 CFR 1435.312 - Establishment of acreage bases under proportionate shares.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Flexible Marketing Allotments For Sugar § 1435.312 Establishment of acreage bases under proportionate... shares as the simple average of the acreage planted and considered planted for harvest for sugar or seed...

  3. 7 CFR 1435.312 - Establishment of acreage bases under proportionate shares.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS SUGAR PROGRAM Flexible Marketing Allotments For Sugar § 1435.312 Establishment of acreage bases under proportionate... shares as the simple average of the acreage planted and considered planted for harvest for sugar or seed...

  4. Geographic, temporal, and age-specific variation in diets of Glaucous Gulls in western Alaska

    USGS Publications Warehouse

    Schmutz, J.A.; Hobson, K.A.

    1998-01-01

    We collected boluses and food remains of adult Glaucous Gulls (Larus hyperboreus) at or near nests and chicks, and digestive tracts from adults at three sites on the Yukon-Kuskokwim Delta, Alaska that differed in proximity to marine and terrestrial foods. We observed both geographic and temporal variation in diet; gulls consumed proportionately more terrestrial prey after peak hatch in late June, and gulls near the coast consumed proportionately more marine prey than gulls at two inland areas. Goslings occurred in > 60% of all samples from these inland areas. We compared these data to those from a previous study in western Alaska and found no marked differences. Evidence for similar patterns of geographic and temporal variation in diet was found using measurements of stable-carbon and nitrogen isotopes in gull and prey tissues. Stable isotope analysis further revealed that adult gulls consumed proportionately more marine prey (saffron cod, Eleginus gracilis) than they fed to their young. Using isotopic models, we estimated that 7-22% and 10-23% of the diet of adult and juvenile Glaucous Gulls, respectively, was comprised of terrestrial species. In addition to significant age-related variation, dietary estimates varied among geographic areas and between pre- and post-hatch periods. Overall, our isotopic estimates of the contribution of terrestrial prey to the diet of Glaucous Gulls was less than what may be inferred from conventional methods of diet analysis. Our study emphasizes the benefit of combining stable-isotope and conventional analyses to infer temporal and geographic changes in diet of wild birds and other organisms.

  5. Locomotor problems among rural elderly population in a District of Aligarh, North India.

    PubMed

    Maroof, Mohd; Ahmad, Anees; Khalique, Najam; Ansari, M Athar

    2017-01-01

    Locomotor functions decline with the age along with other physiological changes. This results in deterioration of the quality of life with decreased social and economic role in the society, as well as increased dependency, for the health care and other basic services. The demographic transition resulting in increased proportion of elderly may pose a burden to the health system. To find the prevalence of locomotor problems among the elderly population, and related sociodemographic factors. The study was a community-based cross-sectional study done at field practice area of Rural Health Training Centre, JN Medical College, AMU, Aligarh, Uttar Pradesh, India. A sample of 225 was drawn from 1018 elderly population aged 60 years and above using systematic random sampling with probability proportionate to size. Sociodemographic characteristics were obtained using pretested and predesigned questionnaire. Locomotor problems were assessed using the criteria used by National Sample Survey Organization. Data were analyzed using SPSS version 20. Chi-square test was used to test relationship of locomotor problems with sociodemographic factors. P <0.05 was considered statistically significant. The prevalence of locomotor problems among the elderly population was 25.8%. Locomotor problems were significantly associated with age, gender, and working status whereas no significant association with literacy status and marital status was observed. The study concluded that approximately one-fourth of the elderly population suffered from locomotor problems. The sociodemographic factors related to locomotor problems needs to be addressed properly to help them lead an independent and economically productive life.

  6. Economic cost and epidemiological characteristics of patients with fibromyalgia claims.

    PubMed

    Robinson, Rebecca L; Birnbaum, Howard G; Morley, Melissa A; Sisitsky, Tamar; Greenberg, Paul E; Claxton, Ami J

    2003-06-01

    Fibromyalgia (FM) is characterized by widespread pain that can lead to significant patient disability, complex management decisions for physicians, and economic burden on society. We investigated the total costs of FM in an employer population. Administrative claims data of a Fortune 100 manufacturer were used to quantify direct (i.e., medical and pharmaceutical claims) and indirect (i.e., disability claims and imputed absenteeism) costs associated with FM. A total of 4699 patients with at least one FM claim between 1996 and 1998 were contrasted with a 10% random sample of the overall beneficiary population. Employee-only subsets of both samples also were drawn. Medical utilization, receipt of prescription drugs, and annual total costs were proportionately similar yet significantly greater among FM claimants than the overall sample (all p < 0.0001). Total annual costs for FM claimants were $5945 versus $2486 for the typical beneficiary (p < 0.0001). Six percent of these costs were attributable to FM-specific claims. The prevalence of disability was twice as high among FM employees than overall employees (p < 0.0001). For every dollar spent on FM-specific claims, the employer spent another $57 to $143 on additional direct and indirect costs. Hidden costs of disability and comorbidities greatly increase the true burden of FM. Regardless of the clinical understanding of FM, when a claim for FM is present, considerable costs are involved. Findings suggest that within the management of FM there may be large cost-offset opportunities for reductions in patient, physician, and employer burdens.

  7. Swift and Certain, Proportionate and Consistent: Key Values of Urine Drug Test Consequences for Probationers.

    PubMed

    Cadwallader, Amy B

    2017-09-01

    Traditionally, urine drug testing (UDT) in the correctional population (both prison and community corrections) has been infrequent, is scheduled, and has a high possibility of delayed results. Of practical relevance is that scheduled testing is ineffective for identifying drug misuse. Of ethical relevance is that consequences of positive scheduled tests can be unpredictable-in the form of overly severe punishment or a lack of treatment options-and that the scheduled testing paradigm is a poor way to change behaviors. More innovative programs now use a UDT paradigm with more frequent, random testing providing rapid results and certain, swift consequences and addiction treatment when warranted or requested. Studies have shown these new programs-the foundation of which is frequent, random UDTs-to significantly reduce drug use, criminal recidivism, and incarceration. © 2017 American Medical Association. All Rights Reserved.

  8. Monitoring health interventions – who's afraid of LQAS?

    PubMed Central

    Pezzoli, Lorenzo; Kim, Sung Hye

    2013-01-01

    Lot quality assurance sampling (LQAS) is used to evaluate health services. Subunits of a population (lots) are accepted or rejected according to the number of failures in a random sample (N) of a given lot. If failures are greater than decision value (d), we reject the lot and recommend corrective actions in the lot (i.e. intervention area); if they are equal to or less than d, we accept it. We used LQAS to monitor coverage during the last 3 days of a meningitis vaccination campaign in Niger. We selected one health area (lot) per day reporting the lowest administrative coverage in the previous 2 days. In the sampling plan we considered: N to be small enough to allow us to evaluate one lot per day, deciding to sample 16 individuals from the selected villages of each health area, using probability proportionate to population size; thresholds and d to vary according to administrative coverage reported; α ≤5% (meaning that, if we would have conducted the survey 100 times, we would have accepted the lot up to five times when real coverage was at an unacceptable level) and β ≤20% (meaning that we would have rejected the lot up to 20 times, when real coverage was equal or above the satisfactory level). We classified all three lots as with the acceptable coverage. LQAS appeared to be a rapid, simple, and statistically sound method for in-process coverage assessment. We encourage colleagues in the field to consider using LQAS in complement with other monitoring techniques such as house-to-house monitoring. PMID:24206650

  9. Monitoring health interventions--who's afraid of LQAS?

    PubMed

    Pezzoli, Lorenzo; Kim, Sung Hye

    2013-11-08

    Lot quality assurance sampling (LQAS) is used to evaluate health services. Subunits of a population (lots) are accepted or rejected according to the number of failures in a random sample (N) of a given lot. If failures are greater than decision value (d), we reject the lot and recommend corrective actions in the lot (i.e. intervention area); if they are equal to or less than d, we accept it. We used LQAS to monitor coverage during the last 3 days of a meningitis vaccination campaign in Niger. We selected one health area (lot) per day reporting the lowest administrative coverage in the previous 2 days. In the sampling plan we considered: N to be small enough to allow us to evaluate one lot per day, deciding to sample 16 individuals from the selected villages of each health area, using probability proportionate to population size; thresholds and d to vary according to administrative coverage reported; α ≤5% (meaning that, if we would have conducted the survey 100 times, we would have accepted the lot up to five times when real coverage was at an unacceptable level) and β ≤20% (meaning that we would have rejected the lot up to 20 times, when real coverage was equal or above the satisfactory level). We classified all three lots as with the acceptable coverage. LQAS appeared to be a rapid, simple, and statistically sound method for in-process coverage assessment. We encourage colleagues in the field to consider using LQAS in complement with other monitoring techniques such as house-to-house monitoring.

  10. New Theoretical Model of Nerve Conduction in Unmyelinated Nerves

    PubMed Central

    Akaishi, Tetsuya

    2017-01-01

    Nerve conduction in unmyelinated fibers has long been described based on the equivalent circuit model and cable theory. However, without the change in ionic concentration gradient across the membrane, there would be no generation or propagation of the action potential. Based on this concept, we employ a new conductive model focusing on the distribution of voltage-gated sodium ion channels and Coulomb force between electrolytes. Based on this new model, the propagation of the nerve conduction was suggested to take place far before the generation of action potential at each channel. We theoretically showed that propagation of action potential, which is enabled by the increasing Coulomb force produced by inflowing sodium ions, from one sodium ion channel to the next sodium channel would be inversely proportionate to the density of sodium channels on the axon membrane. Because the longitudinal number of sodium ion channel would be proportionate to the square root of channel density, the conduction velocity of unmyelinated nerves is theoretically shown to be proportionate to the square root of channel density. Also, from a viewpoint of equilibrium state of channel importation and degeneration, channel density was suggested to be proportionate to axonal diameter. Based on these simple basis, conduction velocity in unmyelinated nerves was theoretically shown to be proportionate to the square root of axonal diameter. This new model would also enable us to acquire more accurate and understandable vision on the phenomena in unmyelinated nerves in addition to the conventional electric circuit model and cable theory. PMID:29081751

  11. Travel-associated infection presenting in Europe (2008-12): an analysis of EuroTravNet longitudinal, surveillance data, and evaluation of the effect of the pre-travel consultation.

    PubMed

    Schlagenhauf, Patricia; Weld, Leisa; Goorhuis, Abraham; Gautret, Philippe; Weber, Rainer; von Sonnenburg, Frank; Lopez-Vélez, Rogelio; Jensenius, Mogens; Cramer, Jakob P; Field, Vanessa K; Odolini, Silvia; Gkrania-Klotsas, Effrossyni; Chappuis, Francois; Malvy, Denis; van Genderen, Perry J J; Mockenhaupt, Frank; Jauréguiberry, Stéphane; Smith, Catherine; Beeching, Nicholas J; Ursing, Johan; Rapp, Christophe; Parola, Philippe; Grobusch, Martin P

    2015-01-01

    Travel is important in the acquisition and dissemination of infection. We aimed to assess European surveillance data for travel-related illness to profile imported infections, track trends, identify risk groups, and assess the usefulness of pre-travel advice. We analysed travel-associated morbidity in ill travellers presenting at EuroTravNet sites during the 5-year period of 2008-12. We calculated proportionate morbidity per 1000 ill travellers and made comparisons over time and between subgroups. We did 5-year trend analyses (2008-12) by testing differences in proportions between subgroups using Pearson's χ(2) test. We assessed the effect of the pre-travel consultation on infection acquisition and outcome by use of proportionate morbidity ratios. The top diagnoses in 32 136 patients, ranked by proportionate morbidity, were malaria and acute diarrhoea, both with high proportionate morbidity (>60). Dengue, giardiasis, and insect bites had high proportionate morbidity (>30) as well. 5-year analyses showed increases in vector borne infections with significant peaks in 2010; examples were increased Plasmodium falciparum malaria (χ(2)=37·57, p<0·001); increased dengue fever (χ(2)=135·9, p<0·001); and a widening geographic range of acquisition of chikungunya fever. The proportionate morbidity of dengue increased from 22 in 2008 to 36 in 2012. Five dengue cases acquired in Europe contributed to this increase. Dermatological diagnoses increased from 851 in 2008 to 1102 in 2012, especially insect bites and animal-related injuries. Respiratory infection trends were dominated by the influenza H1N1 pandemic in 2009. Illness acquired in Europe accounted for 1794 (6%) of all 32 136 cases-mainly, gastrointestinal (634) and respiratory (357) infections. Migration within Europe was associated with more serious infection such as hepatitis C, tuberculosis, hepatitis B, and HIV/AIDS. Pre-travel consultation was associated with significantly lower proportionate morbidity ratios for P falciparum malaria and also for acute hepatitis and HIV/AIDS. The pattern of travel-related infections presenting in Europe is complex. Trend analyses can inform on emerging infection threats. Pre-travel consultation is associated with reduced malaria proportionate morbidity ratios and less severe illness. These findings support the importance and effectiveness of pre-travel advice on malaria prevention, but cast doubt on the effectiveness of current strategies to prevent travel-related diarrhoea. European Centre for Disease Prevention and Control, University Hospital Institute Méditerranée Infection, US Centers for Disease Control and Prevention, and the International Society of Travel Medicine. Copyright © 2015 Elsevier Ltd. All rights reserved.

  12. Comparative Analgesic Efficacy of Oxycodone/Acetaminophen Versus Hydrocodone/Acetaminophen for Short-term Pain Management in Adults Following ED Discharge.

    PubMed

    Chang, Andrew K; Bijur, Polly E; Holden, Lynne; Gallagher, E John

    2015-11-01

    The objective was to test the hypothesis that oxycodone/acetaminophen provides superior analgesia to hydrocodone/acetaminophen for the treatment of acute extremity pain following emergency department (ED) discharge. This was a prospective, randomized, double-blind clinical trial of nonelderly adult ED patients with acute musculoskeletal extremity pain, randomly allocated at discharge to receive oxycodone/acetaminophen (5 mg/325 mg) or hydrocodone/acetaminophen (5 mg/325 mg). The primary outcome was the between-group difference in improvement in numerical rating scale (NRS) pain scores over a 2-hour period following the most recent ingestion of study drug, obtained during telephone contact 24 hours after ED discharge. Secondary outcomes included proportionate decrease in pain, comparative side-effect profiles, and patient satisfaction. A total of 240 patients were enrolled. The final sample consisted of 220 patients, 107 randomly allocated to oxycodone/acetaminophen and 113 to hydrocodone/acetaminophen. At 24 hours after ED discharge, the mean NRS pain scores prior to the most recent dose of outpatient pain medication were 7.8 and 7.9 in the oxycodone/acetaminophen and hydrocodone/acetaminophen groups, respectively. The mean decreases in pain scores over 2 hours were 4.4 NRS units in the oxycodone/acetaminophen group versus 4.0 NRS units in the hydrocodone/acetaminophen group, for a difference of 0.4 NRS units (95% confidence interval = -0.2 to 1.1 NRS units). Satisfaction with the analgesics was similar. This study design could not detect a clinically or statistically significant difference in analgesic efficacy between oxycodone/acetaminophen (5 mg/325 mg) and hydrocodone/acetaminophen (5 mg/325 mg) for treatment of acute musculoskeletal extremity pain in adults following ED discharge. Both opioids reduced pain scores by approximately 50%. © 2015 by the Society for Academic Emergency Medicine.

  13. 7 CFR 1435.313 - Permanent transfer of acreage base histories under proportionate shares.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false Permanent transfer of acreage base histories under... histories under proportionate shares. (a) A sugarcane producer on a farm may transfer all or a portion of the producer's acreage base history of land owned, operated, or controlled to any other farm in the...

  14. 7 CFR 1435.313 - Permanent transfer of acreage base histories under proportionate shares.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false Permanent transfer of acreage base histories under... histories under proportionate shares. (a) A sugarcane producer on a farm may transfer all or a portion of the producer's acreage base history of land owned, operated, or controlled to any other farm in the...

  15. 7 CFR 1435.313 - Permanent transfer of acreage base histories under proportionate shares.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false Permanent transfer of acreage base histories under... histories under proportionate shares. (a) A sugarcane producer on a farm may transfer all or a portion of the producer's acreage base history of land owned, operated, or controlled to any other farm in the...

  16. 7 CFR 1435.313 - Permanent transfer of acreage base histories under proportionate shares.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false Permanent transfer of acreage base histories under... histories under proportionate shares. (a) A sugarcane producer on a farm may transfer all or a portion of the producer's acreage base history of land owned, operated, or controlled to any other farm in the...

  17. 7 CFR 1435.313 - Permanent transfer of acreage base histories under proportionate shares.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Permanent transfer of acreage base histories under... histories under proportionate shares. (a) A sugarcane producer on a farm may transfer all or a portion of the producer's acreage base history of land owned, operated, or controlled to any other farm in the...

  18. Characteristics of proportionate growth observed in instability patterns of miscible fluids

    NASA Astrophysics Data System (ADS)

    Bischofberger, Irmgard; Ramachandran, Radha; Nagel, Sidney R.; Nagel lab Team

    2014-11-01

    As a baby mammal grows, different parts of its body develop at the nearly the same rate and thus to a good approximation in direct proportion to one another. This type of growth is called proportionate growth. As familiar as it appears to us, it is very rarely found in physical systems outside of the biological world. We here show an example of proportionate growth that occurs in the instability formed when a less viscous liquid, of viscosity ηin displaces a more viscous miscible one, of viscosity ηout. We investigate the growth of these patterns in a quasi-two-dimensional geometry. Within a range of viscosity ratios 0.1 <ηin /ηout <0.3, we observe the formation of small blunt structures that form at the edges of an inner circular region devoid of fingers. As the pattern grows, the size of these structures increases in proportion to the size of the inner circle, such that even small details in the shape of the pattern remain essentially unchanged during growth. These characteristics of proportionate growth are reflected in the shape of the interface in the third dimension as well.

  19. Weathering the Storm. Leading Your Organization Through a Pandemic

    DTIC Science & Technology

    2006-11-01

    tasks and can perform them. Proportionate Absenteeism : If your organization’s work can be accomplished over the Internet, then office absenteeism ...reassured that, as basic as they appear, non-medical interventions represent concrete actions that can reduce transmission of the virus. If used...if necessary. Identify those tasks that can be done remotely—via the Internet—and establish secure websites. Proportionate Absenteeism : If your

  20. Increase in iodine deficiency disorder due to inadequate sustainability of supply of iodized salt in District Solan, Himachal Pradesh.

    PubMed

    Kapil, Umesh; Pandey, R M; Jain, Vandana; Kabra, Madhulika; Sareen, Neha; Bhadoria, Ajeet Singh; Vijay, Jyoti; Nigam, Sukirty; Khenduja, Preetika

    2013-12-01

    Himachal Pradesh is a known endemic area for iodine deficiency disorders. A study was conducted in district Solan with the objective of assessing the prevalence of iodine deficiency disorders in school-age children. Thirty clusters were selected by using the probability-proportionate-to-size cluster sampling methodology. Clinical examination of the thyroid of 1898 children in the age-group of 6-12 years was conducted. Urine and salt samples were collected. The total goiter rate was found to be 15.4%. Median urinary iodine excretion level was 62.5 μg/l. Only 39% of the salt samples had iodine content of ≥15 ppm. Mild iodine deficiency was present in the subjects studied.

  1. Modeling optimal treatment strategies in a heterogeneous mixing model.

    PubMed

    Choe, Seoyun; Lee, Sunmi

    2015-11-25

    Many mathematical models assume random or homogeneous mixing for various infectious diseases. Homogeneous mixing can be generalized to mathematical models with multi-patches or age structure by incorporating contact matrices to capture the dynamics of the heterogeneously mixing populations. Contact or mixing patterns are difficult to measure in many infectious diseases including influenza. Mixing patterns are considered to be one of the critical factors for infectious disease modeling. A two-group influenza model is considered to evaluate the impact of heterogeneous mixing on the influenza transmission dynamics. Heterogeneous mixing between two groups with two different activity levels includes proportionate mixing, preferred mixing and like-with-like mixing. Furthermore, the optimal control problem is formulated in this two-group influenza model to identify the group-specific optimal treatment strategies at a minimal cost. We investigate group-specific optimal treatment strategies under various mixing scenarios. The characteristics of the two-group influenza dynamics have been investigated in terms of the basic reproduction number and the final epidemic size under various mixing scenarios. As the mixing patterns become proportionate mixing, the basic reproduction number becomes smaller; however, the final epidemic size becomes larger. This is due to the fact that the number of infected people increases only slightly in the higher activity level group, while the number of infected people increases more significantly in the lower activity level group. Our results indicate that more intensive treatment of both groups at the early stage is the most effective treatment regardless of the mixing scenario. However, proportionate mixing requires more treated cases for all combinations of different group activity levels and group population sizes. Mixing patterns can play a critical role in the effectiveness of optimal treatments. As the mixing becomes more like-with-like mixing, treating the higher activity group in the population is almost as effective as treating the entire populations since it reduces the number of disease cases effectively but only requires similar treatments. The gain becomes more pronounced as the basic reproduction number increases. This can be a critical issue which must be considered for future pandemic influenza interventions, especially when there are limited resources available.

  2. The Behavioral Economics and Neuroeconomics of Alcohol Use Disorders

    PubMed Central

    MacKillop, James

    2016-01-01

    Background Behavioral economics and neuroeconomics bring together perspectives and methods from psychology, economics, and cognitive neuroscience to understand decision making and choice behavior. Extending an operant behavioral theoretical framework, these perspectives have increasingly been applied to understanding alcohol use disorders (AUDs) and this review surveys the theory, methods, and findings from this approach. The focus is on three key behavioral economic concepts: delay discounting (i.e., preferences for smaller immediate rewards relative to larger delayed rewards), alcohol demand (i.e., alcohol reinforcing value), and proportionate alcohol-related reinforcement (i.e., relative amount of psychosocial reinforcement associated with alcohol use). Findings Delay discounting has been linked to AUDs in both cross-sectional and longitudinal studies, and has been investigated cross-sectionally using neuroimaging. Alcohol demand and proportionate alcohol-related reinforcement have both been robustly associated with drinking and alcohol misuse cross-sectionally, but not over time. Both have also been found to predict treatment response to brief interventions. Alcohol demand has also been used to enhance the measurement of acute motivation for alcohol in laboratory studies. Interventions that focus on reducing the value of alcohol by increasing alternative reinforcement and response cost have been found to be efficacious, albeit in relatively small numbers of randomized controlled trials (RCTs). Mediators and moderators of response to these interventions have not been extensively investigated. Future Directions The application of behavioral economics and neuroeconomics to AUDs has given rise to an extensive body of empirical work, although significant gaps in knowledge remain. In particular, there is a need for more longitudinal investigations to clarify the etiological roles of these behavioral economic processes, especially alcohol demand and proportionate alcohol reinforcement. Additional RCTs are needed to extend and generalize the findings from reinforcement-based interventions and to investigate mediators and moderators of treatment success for optimization. Applying neuroeconomics to AUDs remains at an early stage and has been primarily descriptive to date, but has high potential for important translational insights in the future. The same is true for using these behavioral economic indicators to understand genetic influences on AUDs. PMID:26993151

  3. Molecular Study of a Hoxa2 Gain-of-Function in Chondrogenesis: A Model of Idiopathic Proportionate Short Stature

    PubMed Central

    Deprez, Pierre M. L.; Nichane, Miloud G.; Lengelé, Benoît G.; Rezsöhazy, René; Nyssen-Behets, Catherine

    2013-01-01

    In a previous study using transgenic mice ectopically expressing Hoxa2 during chondrogenesis, we associated the animal phenotype to human idiopathic proportionate short stature. Our analysis showed that this overall size reduction was correlated with a negative influence of Hoxa2 at the first step of endochondral ossification. However, the molecular pathways leading to such phenotype are still unknown. Using protein immunodetection and histological techniques comparing transgenic mice to controls, we show here that the persistent expression of Hoxa2 in chondrogenic territories provokes a general down-regulation of the main factors controlling the differentiation cascade, such as Bapx1, Bmp7, Bmpr1a, Ihh, Msx1, Pax9, Sox6, Sox9 and Wnt5a. These data confirm the impairment of chondrogenic differentiation by Hoxa2 overexpression. They also show a selective effect of Hoxa2 on endochondral ossification processes since Gdf5 and Gdf10, and Bmp4 or PthrP were up-regulated and unmodified, respectively. Since Hoxa2 deregulation in mice induces a proportionate short stature phenotype mimicking human idiopathic conditions, our results give an insight into understanding proportionate short stature pathogenesis by highlighting molecular factors whose combined deregulation may be involved in such a disease. PMID:24129174

  4. A cross-sectional study to assess the patient safety culture in the Palestinian hospitals: a baseline assessment for quality improvement.

    PubMed

    Elsous, Aymen; Akbari Sari, Ali; Rashidian, Arash; Aljeesh, Yousef; Radwan, Mahmoud; AbuZaydeh, Hatem

    2016-12-01

    To measure and establish a baseline assessment of the patient safety culture in the Palestinian hospitals. A cross-sectional descriptive study using the Arabic version of the Safety Attitude Questionnaire (Short Form 2006). A total of 339 nurses and physicians returned the questionnaire out of 370 achieving a response rate of 91.6%. Four public general hospitals in the Gaza Strip, Palestine. Nurses and physicians were randomly selected using a proportionate random sampling. Data analysis performed using Statistical Package for the Social Sciences software version 20, and p value less than 0.05 was statistically significant. Current status of patient safety culture among healthcare providers and percentage of positive attitudes. Male to female ratio was 2.16:1, and mean age was 36.5 ± 9.4 years. The mean score of Arabic Safety Attitude Questionnaire across the six dimensions on 100-point scale ranged between 68.5 for Job Satisfaction and 48.5 for Working Condition. The percentage of respondents holding a positive attitude was 34.5% for Teamwork Climate, 28.4% for Safety Climate, 40.7% for Stress Recognition, 48.8% for Job Satisfaction, 11.3% for Working Conditions and 42.8% for Perception of Management. Healthcare workers holding positive attitudes had better collaboration with co-workers than those without positive attitudes. Findings are useful to formulate a policy on patient safety culture and targeted a specific safety culture dimension to improve the safety of patients and improve the clinical outcomes within healthcare organisations.

  5. Age and sex prevalence of infectious dermatoses among primary school children in a rural South-Eastern Nigerian community

    PubMed Central

    Kalu, Eziyi Iche; Wagbatsoma, Victoria; Ogbaini-Emovon, Ephraim; Nwadike, Victor Ugochukwu; Ojide, Chiedozie Kingsley

    2015-01-01

    Introduction Various dermatoses, due to their morbidity characteristics, have been shown to negatively impact on learning. The most epidemiologically important seem to be the infectious types because of their transmissibility and amenability to simple school-health measures. The aim of this study was to assess the prevalence and sex/age correlates of infectious dermatoses in a rural South-eastern Nigerian community. Methods The pupils were proportionately recruited from the three primary schools based on school population. Stratified simple random sampling method was adopted and a table of random numbers was used to select required pupils from each arm. Clinical and laboratory examination was done to establish diagnoses of infectious skin disease. Data collected were analyzed using SPSS version 16. Results The 400 pupils consisted of 153 males and 247 females. Age range was between 6 and 12 years. The prevalence of infectious dermatoses was 72.3%. The five most prevalent clinical forms of infectious dermatoses, in order of decreasing prevalence, were tinea capitis (35.2%), scabies (10.5%), tinea corporis (5.8%), tinea pedis (5.5%), and impetigo (5.0%). More cases, generally, occurred among males than females (80.4% vs 67.2%)); while some specific clinical types, pediculosis and seborrheic dermatitis, exhibited predilection for females. Pyodermas and scabies were significantly more prevalent in the 7-9 age-group; while tinea capitis, tinea corporis, seborrheic dermatitis and pediculosis were more associated with ≥10 age-group. Conclusion Infectious dermatoses were highly prevalent in the surveyed population. Many of the clinical types exhibited sex- and age-specificity. PMID:26430479

  6. Burnout among nurses working in medical and educational centers in Shahrekord, Iran

    PubMed Central

    Moghaddasi, Jaefar; Mehralian, Hossein; Aslani, Yousef; Masoodi, Reza; Amiri, Masoud

    2013-01-01

    Background: Nursing burnout is the main characteristic of job stress that is a delayed reaction to chronic stressful situations in the workplace which could affect nurses who do not have sufficient emotional energy to cope and communicate with different types of patients. There is also sometimes this belief that they do not have the required capabilities for their jobs. The aim of this study was the evaluation of burnout among nurses working in medical and educational centers in Shahrekord. Materials and Methods: This descriptive study was performed on 340 nurses working in medical and educational centers in Shahrekord in 2009. Samples were selected using proportionate random sampling. Demographic information and the Maslach Burnout Inventory (MBI) were filled in for all nurses. Results: Burnout was considerable among nurses. The results showed that 34.6, 28.8, and 95.7% of the nurses had emotional exhaustion (EE), high depersonalization (DP), and high reduced personal accomplishment (PA), respectively. The mean scores (± standard deviation) for EE, DP, and PA were 22.77 (12.44), 6.99 (6.23), and 32.20 (9.26), respectively. Conclusions: Our results showed that burnout was noticeable among nurses working in medical and educational centers in Shahrekord. Disproportionate relationship between the number of nurses, workload, and income was the most important factor affecting nursing burnout. Due to the importance of nursing in the health-care system, policy makers should adopt suitable strategies for increasing the satisfaction of nurses. PMID:24403925

  7. Serum Copper Status in School-Age Children and Pregnant Women in China Nutrition and Health Survey 2010-2012.

    PubMed

    Liu, Xiaobing; Piao, Jianhua; Zhang, Yu; Li, Min; Li, Weidong; Yang, Lichen; Yang, Xiaoguang

    2016-10-01

    Serum copper is an insensitive but reliable biomarker reflecting the change of copper nutritional status in both depleted and replete populations. The current study aimed to establish the reference values of serum copper in school-age children and pregnant women in China and to explore the adequate range of serum copper for both these two categories of people. A multistage, stratified, random sampling combined with probability proportionate to regional size sampling method was employed. A total of 4019 subjects (2736 school-age children and 1283 pregnant women) were selected from China Nutrition and Health Survey 2010-2012 (CNHS 2010-2012). The concentration of serum copper was determined by sector field inductively coupled plasma mass spectrometry (SF-ICP-MS). The adequate range of serum copper was determined by the logistic sigmoid saturation curve of the median derivatives. The median concentration of serum copper was 1140.9 μg/L with a range of 746.7-1677.6 μg/L for school-age children and 1933.4 μg/L with a range of 947.4-3391.4 μg/L for pregnant women. The adequate range of serum copper was 905.7-1440.7 μg/L for school-age children and 1308.8-2537.8 μg/L for pregnant women. These parameters represent an essential prerequisite for the assessment of copper nutritional status, as well as nutrition interventions.

  8. Workplace Violence and its Associated Factors among Nurses.

    PubMed

    Pandey, Manisha; Bhandari, Tulsi Ram; Dangal, Ganesh

    2018-01-01

    Workplace violence among nurses is prevalent worldwide. If nurses become aware of the workplace violence and its risk factors then only they can protect themselves. This study assessed the prevalence of workplace violence and its associated factors among nurses in Pokhara, Nepal. A hospital-based descriptive cross-sectional study was conducted in Pokhara. The required sample size of the study was 200 nurses. We adopted self-administered questionnaire developed by International Labor Office, International Council of Nurses, World Health Organization (WHO), and Public Services International. Out of 21 hospitals of Pokhara, we selected five hospitals using simple random sampling method. The number of nurses in each hospital was fixed proportionately considering the total number of employed nurses. Individual nurses were selected on the first meet first basis to gain the required number. Two-thirds (64.5%) nurses experienced some type of violence in the last six months at their workplace. The proportion of verbal violence was higher (61.5%) compared to the physical (15.5%) and sexual violence (9%). Most perpetrators of the violence were the relatives of patients and hospital employees. Age of nurses and working stations had statistically significant association with workplace violence (p-value < 0.05). Workplace violence among nurses is a noteworthy problem in Pokhara whereas nearly two-thirds of nurses faced some type of violence in last six months. It is an urge to widen awareness level of nurses on the violence thus, they can take precaution themselves and ask hospital administration and other stakeholders to address the workplace violence.

  9. Knowledge of medical students of Tehran University of Medical Sciences regarding plagiarism.

    PubMed

    Gharedaghi, Mohammad Hadi; Nourijelyani, Keramat; Salehi Sadaghiani, Mohammad; Yousefzadeh-Fard, Yashar; Gharedaghi, Azadeh; Javadian, Pouya; Morteza, Afsaneh; Andrabi, Yasir; Nedjat, Saharnaz

    2013-07-13

    The core concept of plagiarism is defined as the use of other people's ideas or words without proper acknowledgement. Herein, we used a questionnaire to assess the knowledge of students of Tehran University of Medical Sciences (TUMS) regarding plagiarism and copyright infringement. The questionnaire comprised 8 questions. The first six questions of the questionnaire were translations of exercises of a book about academic writing and were concerning plagiarism in preparing articles. Questions number 7 and 8 (which were concerning plagiarism in preparing Microsoft PowerPoint slideshows and copyright infringement, respectively) were developed by the authors of the present study. The validity of the questionnaire was approved by five experts in the field of epidemiology and biostatistics. A pilot study consisting of a test and retest was carried to assess the reliability of the questionnaire. The sampling method was stratified random sampling, and the questionnaire was handed out to 74 interns of TUMS during July and August 2011. 14.9% of the students correctly answered the first six questions. 44.6% of the students were adequately familiar with proper referencing in Microsoft PowerPoint slideshows. 16.2% of the students understood what constitutes copyright infringement. The number of correctly answered questions by the students was directly proportionate to the number of their published articles. Knowledge of students of TUMS regarding plagiarism and copyright infringement is quite poor. Courses with specific focus on plagiarism and copyright infringement might help in this regard.

  10. Impact of national smokefree environments laws on teachers, schools and early childhood centres.

    PubMed

    Watson, Donna; Glover, Marewa; McCool, Judith; Bullen, Chris; Adams, Brian; Min, Sandar

    2011-12-01

    New Zealand's (NZ) smokefree legislation, implemented on 1 January 2004, requires that all school and early childhood centre buildings and grounds are 100% smokefree; one aim being to prevent young people being influenced by seeing people (including teachers) smoke there. This study, conducted in 2008, investigated teachers'smoking behaviour and perceived adherence to the legislation. A national NZ cross-sectional survey of 2,004 teachers (oversampling Māori), who were randomly selected from the electoral roll of registered voters and sent postal invitations to complete an anonymous survey. The response rate was 70%. Current smokers numbered 7%, and proportionately more Maori and Pacific Island teachers (12% each) smoked than European/Other teachers (7%). Of current smokers, 37% smoked non-daily. Smokers smoked less on work than non-work days. Introducing smokefree legislation was associated with teachers changing when they smoked, cutting down, quitting or trying to quit. Perceived compliance with the legislation was high, although 30% of teachers reported seeing staff smoking. Proportionately, significantly more teachers from low than from high socioeconomic schools perceived poor compliance and staff visibly smoking. Smokefree legislation affects people's smoking behaviour. Smoking in NZ is becoming confined to population subgroups defined by socioeconomic status and ethnicity. Our findings argue for supporting cessation among those who work with children and young people, and for targeting support at school communities in areas of low socioeconomic status or with large populations of Māori or Pacific peoples.

  11. 3M syndrome: an easily recognizable yet underdiagnosed cause of proportionate short stature.

    PubMed

    Al-Dosari, Mohammed S; Al-Shammari, Muneera; Shaheen, Ranad; Faqeih, Eissa; Alghofely, Mohammed A; Boukai, Ahmad; Alkuraya, Fowzan S

    2012-07-01

    To characterize, via clinical and molecul criteria, a cohort of patients with 3M syndrome and thereby increase awareness of this syndrome as a recognizable cause of proportionate short stature. We conducted a case series of patients referred to clinical genetics for proportionate short stature. CUL7, OBSL1, and CCDC8 genes were clinically phenotyped and sequenced. In 6 Saudi families with 3M syndrome, we identified three CUL7, one OBSL1, and one CCDC8 novel mutations, which we show result in a remarkably similar clinical phenotype. Despite their typical and easily discernible clinical phenotype, all these patients have been extensively investigated for alternative causes of their short stature and received erroneous diagnoses. Increased awareness about this syndrome among pediatricians and endocrinologists is needed to avoid a costly and unnecessary diagnostic odyssey. Copyright © 2012 Mosby, Inc. All rights reserved.

  12. Pattern formation with proportionate growth

    NASA Astrophysics Data System (ADS)

    Dhar, Deepak

    It is a common observation that as baby animals grow, different body parts grow approximately at same rate. This property, called proportionate growth is remarkable in that it is not encountered easily outside biology. The models of growth that have been studied in Physics so far, e.g diffusion -limited aggregation, surface deposition, growth of crystals from melt etc. involve only growth at the surface, with the inner structure remaining frozen. Interestingly, patterns formed in growing sandpiles provide a very wide variety of patterns that show proportionate growth. One finds patterns with different features, with sharply defined boundaries. In particular, even with very simple rules, one can produce patterns that show striking resemblance to those seen in nature. We can characterize the asymptotic pattern exactly in some special cases. I will discuss in particular the patterns grown on noisy backgrounds. Supported by J. C. Bose fellowship from DST (India).

  13. Delivering proportionate governance in the era of eHealth

    PubMed Central

    Sethi, Nayha; Laurie, Graeme T.

    2013-01-01

    This article advances a principled proportionate governance model (PPGM) that overcomes key impediments to using health records for research. Despite increasing initiatives for maximising benefits of data linkage, significant challenges remain, including a culture of caution around data sharing and linkage, failure to make use of flexibilities within the law and failure to incorporate intelligent iterative design. The article identifies key issues for consideration and posits a flexible and accessible governance model that provides a robust and efficient means of paying due regard to both privacy and the public interests in research. We argue that proportionate governance based on clear guiding principles accurately gauges risks associated with data uses and assigns safeguards accordingly. This requires a clear articulation of roles and responsibilities at all levels of decision-making and effective training for researchers and data custodians. Accordingly, the PPGM encourages and supports defensible judgements about data linkage in the public interest. PMID:24634569

  14. Deducing growth mechanisms for minerals from the shapes of crystal size distributions

    USGS Publications Warehouse

    Eberl, D.D.; Drits, V.A.; Srodon, J.

    1998-01-01

    Crystal size distributions (CSDs) of natural and synthetic samples are observed to have several distinct and different shapes. We have simulated these CSDs using three simple equations: the Law of Proportionate Effect (LPE), a mass balance equation, and equations for Ostwald ripening. The following crystal growth mechanisms are simulated using these equations and their modifications: (1) continuous nucleation and growth in an open system, during which crystals nucleate at either a constant, decaying, or accelerating nucleation rate, and then grow according to the LPE; (2) surface-controlled growth in an open system, during which crystals grow with an essentially unlimited supply of nutrients according to the LPE; (3) supply-controlled growth in an open system, during which crystals grow with a specified, limited supply of nutrients according to the LPE; (4) supply- or surface-controlled Ostwald ripening in a closed system, during which the relative rate of crystal dissolution and growth is controlled by differences in specific surface area and by diffusion rate; and (5) supply-controlled random ripening in a closed system, during which the rate of crystal dissolution and growth is random with respect to specific surface area. Each of these mechanisms affects the shapes of CSDs. For example, mechanism (1) above with a constant nucleation rate yields asymptotically-shaped CSDs for which the variance of the natural logarithms of the crystal sizes (??2) increases exponentially with the mean of the natural logarithms of the sizes (??). Mechanism (2) yields lognormally-shaped CSDs, for which ??2 increases linearly with ??, whereas mechanisms (3) and (5) do not change the shapes of CSDs, with ??2 remaining constant with increasing ??. During supply-controlled Ostwald ripening (4), initial lognormally-shaped CSDs become more symmetric, with ??2 decreasing with increasing ??. Thus, crystal growth mechanisms often can be deduced by noting trends in ?? versus ??2 of CSDs for a series of related samples.

  15. Vintage meets contemporary: Use of rigid TBNA in the era of real-time imaging - first report from India.

    PubMed

    Khan, Ajmal; Nath, Alok; Lal, Hira; Krishnani, Narendra; Agarwal, Aarti

    2018-01-01

    In the modern era, real-time imaging-guided transbronchial needle aspiration (TBNA) has completely replaced the traditional surgical approaches to sample the mediastinal lesions for diagnosis and cancer staging. However, there is a limited role of these innovations in the presence of critical airway narrowing due to a further decrease in cross-sectional area of the airway proportionate to the outer diameters of the scope. Rigid TBNA with airway control by rigid bronchoscopy is one alternative which can be used for mediastinal sampling when modern technique is impracticable. Herein, we report the use of rigid TBNA, an underutilized old method to sample the mediastinal lesion in a patient with severe orthopnea secondary to tracheal compression by mediastinal mass.

  16. Relationship between staff-reported culture change and occupancy rate and organizational commitment among nursing homes in South Korea.

    PubMed

    Lee, Minhong; Choi, Jae-Sung; Lim, Jinseop; Kim, Young Sun

    2013-04-01

    This study aims to examine culture change in nursing homes in South Korea and to identify the outcomes of culture change implementation. Data were taken from survey responses from 223 top- or mid-level staff among nursing homes in South Korea that were selected through a proportionate random-stratified sampling method from four regions nationwide. Culture change in nursing homes was operationalized by five person-directed care (PDC) constructs and three organizational environment constructs, and outcome quality was indicated by changes to occupancy rate and organizational commitment. After controlling for facility characteristics, the effect of staff-reported culture change on occupancy rate and organizational commitment was analyzed through the multiple-regression method. Consistent with previous research, this study revealed positive effects of culture change for nursing homes in South Korea. The study found that staff-reported culture change correlated with occupancy rate and organizational commitment. Given that culture change variables were significantly related to occupancy rate and organizational commitment, the findings of the study provide a persuasive argument that policies and/or programs to support culture change in nursing homes should be enhanced. Management-level workers in these facilities should have the skills and knowledge to foster more PDC and a more person-directed environment.

  17. A novel variant of FGFR3 causes proportionate short stature.

    PubMed

    Kant, Sarina G; Cervenkova, Iveta; Balek, Lukas; Trantirek, Lukas; Santen, Gijs W E; de Vries, Martine C; van Duyvenvoorde, Hermine A; van der Wielen, Michiel J R; Verkerk, Annemieke J M H; Uitterlinden, André G; Hannema, Sabine E; Wit, Jan M; Oostdijk, Wilma; Krejci, Pavel; Losekoot, Monique

    2015-06-01

    Mutations of the fibroblast growth factor receptor 3 (FGFR3) cause various forms of short stature, of which the least severe phenotype is hypochondroplasia, mainly characterized by disproportionate short stature. Testing for an FGFR3 mutation is currently not part of routine diagnostic testing in children with short stature without disproportion. A three-generation family A with dominantly transmitted proportionate short stature was studied by whole-exome sequencing to identify the causal gene mutation. Functional studies and protein modeling studies were performed to confirm the pathogenicity of the mutation found in FGFR3. We performed Sanger sequencing in a second family B with dominant proportionate short stature and identified a rare variant in FGFR3. Exome sequencing and/or Sanger sequencing was performed, followed by functional studies using transfection of the mutant FGFR3 into cultured cells; homology modeling was used to construct a three-dimensional model of the two FGFR3 variants. A novel p.M528I mutation in FGFR3 was detected in family A, which segregates with short stature and proved to be activating in vitro. In family B, a rare variant (p.F384L) was found in FGFR3, which did not segregate with short stature and showed normal functionality in vitro compared with WT. Proportionate short stature can be caused by a mutation in FGFR3. Sequencing of this gene can be considered in patients with short stature, especially when there is an autosomal dominant pattern of inheritance. However, functional studies and segregation studies should be performed before concluding that a variant is pathogenic. © 2015 European Society of Endocrinology.

  18. Evaluating Behavioral Economic Models of Heavy Drinking Among College Students.

    PubMed

    Acuff, Samuel F; Soltis, Kathryn E; Dennhardt, Ashley A; Berlin, Kristoffer S; Murphy, James G

    2018-05-14

    Heavy drinking among college students is a significant public health concern that can lead to profound social and health consequences, including alcohol use disorder. Behavioral economics posits that low future orientation and high valuation of alcohol (alcohol demand) combined with deficits in alternative reinforcement increase the likelihood of alcohol misuse (Bickel et al., 2011). Despite this, no study has examined the incremental utility of all three variables simultaneously in a comprehensive model METHOD: The current study uses structural equation modeling to test the associations between behavioral economic variables - alcohol demand (latent), future orientation (measured with a delay discounting task and the Consideration of Future Consequences (CFC) scale), and proportionate substance-related reinforcement - and alcohol consumption and problems among 393 heavy drinking college students. Two models are tested: 1) an iteration of the reinforcer pathology model that includes an interaction between future orientation and alcohol demand; and 2) an alternative model evaluating the interconnectedness of behavioral economic variables in predicting problematic alcohol use RESULTS: The interaction effects in model 1 were nonsignificant. Model 2 suggests that greater alcohol demand and proportionate substance-related reinforcement is associated with greater alcohol consumption and problems. Further, CFC was associated with alcohol-related problems and lower proportionate substance-related reinforcement but was not significantly associated with alcohol consumption or alcohol demand. Finally, greater proportionate substance-related reinforcement was associated with greater alcohol demand CONCLUSIONS: Our results support the validity of the behavioral economic reinforcer pathology model as applied to young adult heavy drinking. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  19. Palliative Sedation in Patients With Cancer.

    PubMed

    Maltoni, Marco; Setola, Elisabetta

    2015-10-01

    Palliative sedation involves the use of sedative medication to relieve refractory symptoms in patients by reducing their level of consciousness. Although it is considered an acceptable clinical practice from most ethical points of view, palliative sedation is still a widely debated procedure and merits better understanding. The relevant medical literature pertaining to palliative sedation was analyzed and reviewed from various technical, relational, and bioethical perspectives. Proportionate palliative sedation is considered to be the most clinically appropriate modality for performing palliative sedation. However, guidelines must be followed to ensure that it is performed correctly. Benzodiazepines represent the first therapeutic option and careful monitoring of dosages is essential to avoid oversedation or undersedation. Proportionate palliative sedation is used to manage and relieve refractory symptoms in patients with cancer during their last days or hours of life. Evidence suggests that its use has no detrimental effect on survival. A different decision-making process is used to manage the withdrawal of hydration than the process used to determine whether proportionate palliative sedation is appropriate. Communication between patients, their relatives, and the health care staff is important during this medical intervention.

  20. Forensic Medicine in South Africa: Associations between Medical Practice and Legal Case Progression and Outcomes in Female Murders

    PubMed Central

    Abrahams, Naeemah; Jewkes, Rachel; Martin, Lorna J.; Mathews, Shanaaz

    2011-01-01

    Background Forensic medicine has been largely by-passed by the tide of health systems research and evidence based medicine. Murder victims form a central part of forensic medical examiners' case load, and women murdered by intimate partners are an important subgroup, representing the most severe form and consequence of intimate partner violence. Our aim was to describe the epidemiology of female murder in South Africa (by intimate and non-intimate partners); and to describe and compare autopsy findings, forensic medical management of cases and the contribution of these to legal outcomes. Methods We did a retrospective national study in a proportionate random sample of 25 medico-legal laboratories to identify all homicides in 1999 of women aged 14 years and over. Data were abstracted from the mortuary file and autopsy report, and collected from a police interview. Findings In 21.5% of cases the perpetrator was convicted. Factors associated with a conviction for the female murders included having a history of intimate partner violence 1.18 (95%CI: 0.16–2.20), weapon recovered 1.36 (95% CI:0.58–2.15) and a detective visiting the crime scene 1.57 (95% CI:0.14–3.00). None of the forensic medical activities increased the likelihood of a conviction. Conclusion The findings raise important questions about the role of forensic medicine in these cases. PMID:22194868

  1. Forensic medicine in South Africa: associations between medical practice and legal case progression and outcomes in female murders.

    PubMed

    Abrahams, Naeemah; Jewkes, Rachel; Martin, Lorna J; Mathews, Shanaaz

    2011-01-01

    Forensic medicine has been largely by-passed by the tide of health systems research and evidence based medicine. Murder victims form a central part of forensic medical examiners' case load, and women murdered by intimate partners are an important subgroup, representing the most severe form and consequence of intimate partner violence. Our aim was to describe the epidemiology of female murder in South Africa (by intimate and non-intimate partners); and to describe and compare autopsy findings, forensic medical management of cases and the contribution of these to legal outcomes. We did a retrospective national study in a proportionate random sample of 25 medico-legal laboratories to identify all homicides in 1999 of women aged 14 years and over. Data were abstracted from the mortuary file and autopsy report, and collected from a police interview. In 21.5% of cases the perpetrator was convicted. Factors associated with a conviction for the female murders included having a history of intimate partner violence 1.18 (95%CI: 0.16-2.20), weapon recovered 1.36 (95% CI:0.58-2.15) and a detective visiting the crime scene 1.57 (95% CI:0.14-3.00). None of the forensic medical activities increased the likelihood of a conviction. The findings raise important questions about the role of forensic medicine in these cases.

  2. Shared Decision Making and Other Variables as Correlates of Satisfaction with Health Care Decisions in a United States National Survey

    PubMed Central

    Wills, Celia E.; Holloman, Christopher; Olson, Jacklyn; Hechmer, Catherine; Miller, Carla K.; Duchemin, Anne-Marie

    2012-01-01

    Objective The purpose of this study was to examine the relationship between shared decision-making (SDM) and satisfaction with decision (SWD) within a larger survey of patient decision-making in health care consultations. Methods A randomly selected age-proportionate national sample of adults (aged 21–70 years) stratified on race, ethnicity, and gender (N = 488) was recruited from a health research volunteer registry and completed an online survey with reference to a recent health consultation. Measures included the Shared Decision Making-9 questionnaire (SDM-Q-9), Satisfaction With Decision (SWD) scale, sociodemographic, health, and other standardized decision-making measures. Forward selection weighted multiple regression analysis was used to model correlates of SWD. Results After controlling for sociodemographic variables, SDM-Q-9 total score was associated with SWD, adjusted R2 = .368, p < .001. Three of nine SDM-Q-9 items accounted for significant proportions of variance in SWD. Conclusion SDM was positively associated with SWD and was strongest for three areas of SDM: patients being helped in a health care consultation with understanding information, with treatment preference elicitation, and with weighing options thoroughly. Practice Implications By identifying variables such as SDM that are associated with SWD, health care interventions can better target modifiable factors to enhance satisfaction and other outcomes. PMID:22410642

  3. Women's attitudes toward mode of delivery in South Korea--a society with high cesarean section rates.

    PubMed

    Lee, Sang-Il; Khang, Young-Ho; Lee, Moo-Song

    2004-06-01

    In South Korea, cesarean section rates (i.e., the proportion of all live births delivered by cesarean section) approached 40 percent in 2000. The relative contribution of physicians and women to this high rate has been a source of debate. This study explored attitudes toward mode of delivery among South Korean women. A nationwide cross-sectional telephone survey of 505 Korean women aged 20 to 49 years was conducted using a proportionate quota and systematic random sampling method. The response rate was 57.3 percent. Data were collected using a structured questionnaire consisting of 7 questions about vaginal and cesarean delivery. Over 95 percent of women preferred vaginal delivery during pregnancy and were willing to recommend this method to others. Of the women who delivered by cesarean section, 10.6 percent stated that they had requested a cesarean birth. Attitudes toward vaginal or cesarean delivery differed significantly according to a woman's education level. Most study participants showed more favorable attitudes toward vaginal delivery than cesarean delivery. This result does not support the assumption that the upsurge of cesarean section rates in South Korea is associated with women's positive attitudes toward cesarean section. The main cause of the rapid rise of cesarean section rates in South Korea during the past two decades have its origins in health care practitioners and the health care system in which they work.

  4. Shared decision making and other variables as correlates of satisfaction with health care decisions in a United States national survey.

    PubMed

    Glass, Katherine Elizabeth; Wills, Celia E; Holloman, Christopher; Olson, Jacklyn; Hechmer, Catherine; Miller, Carla K; Duchemin, Anne-Marie

    2012-07-01

    The purpose of this study was to examine the relationship between shared decision-making (SDM) and satisfaction with decision (SWD) within a larger survey of patient decision-making in health care consultations. A randomly selected age-proportionate national sample of adults (aged 21-70 years) stratified on race, ethnicity, and gender (N=488) was recruited from a health research volunteer registry and completed an online survey with reference to a recent health consultation. Measures included the shared decision making-9 questionnaire (SDM-Q-9), Satisfaction With Decision (SWD) scale, sociodemographic, health, and other standardized decision-making measures. Forward selection weighted multiple regression analysis was used to model correlates of SWD. After controlling for sociodemographic variables, SDM-Q-9 total score was associated with SWD, adjusted R(2)=.368, p<.001. Three of nine SDM-Q-9 items accounted for significant proportions of variance in SWD. SDM was positively associated with SWD and was strongest for three areas of SDM: patients being helped in a health care consultation with understanding information, with treatment preference elicitation, and with weighing options thoroughly. By identifying variables such as SDM that are associated with SWD, health care interventions can better target modifiable factors to enhance satisfaction and other outcomes. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  5. Gender issues in a cataract surgical population in South India.

    PubMed

    Joseph, Sanil; Ravilla, Thulasiraj; Bassett, Ken

    2013-04-01

    To investigate patterns and characteristics of men and women who used different cataract surgery payment streams in a South Indian hospital. We randomly sampled patients with age-related cataract aged 40 years and over from three routine cataract surgical service streams: walk-in paying, walk-in subsidized and free camp. Presenting visual acuity (VA) and cataract surgical details were obtained from routine hospital records. Demographic and socioeconomic factors were collected from patient interviews. Multiple logistic regression was used to investigate factors associated with use of different streams with walk-in paying as the reference group. There were 7076 eligible admissions (3742 women and 3334 men). Proportionately more women than men attended the walk-in subsidized (56%) or free camp sections (55%) compared to the walk-in paying stream (42%, odds ratio, OR, 1.40 95% confidence interval, CI, 1.25-1.57 and OR 1.33 95% CI 1.19-1.49, respectively). After adjustment for socioeconomic factors (illiteracy, not being in paid work), rural residence and poor presenting VA, OR for women compared to men for the walk-in subsided stream was 1.02, (95% CI 0.87-1.18) and for the free camp 0.94 (95% CI 0.80-1.11). Our results indicate that women are underrepresented in the paying section, reflecting their poorer socioeconomic and educational statuses.

  6. Assessment of motivation levels and associated factors among the nursing staff of tertiary-level government hospitals.

    PubMed

    Pandey, Rahul; Goel, Sonu; Koushal, Vipin

    2018-04-15

    The present study assessed the motivation level of nurses working in 3 highly decorated tertiary-level government hospitals of India and also underpins the factors attributing to motivation levels. A sequential mixed-method design was used in this study wherein 400 nurses working in 5 units of nursing care in the hospitals were enrolled based upon proportionate random stratified sampling techniques. A self-administered questionnaire with Likert scale was developed based upon scale used by Mbindyo et al. The attributes of motivation were then categorized into external and internal attributes. For the qualitative component, participants with varied responses in quantitative data were selected and interviewed. Overall mean motivation score of the nursing staff was found 3.57 ± 0.93, which was higher for extrinsic motivational attributes (3.67 ± 0.88) as compared with intrinsic attributes (3.47 ± 0.98). The intrinsic motivational attribute of organizational commitment was rated highest followed by general motivation, conscientiousness, and self-efficacy. Personal issues, timeliness, and burnout were prime discouraging attributes among study participants. Sociodemographic characteristics and work profile characteristics showed significant relationship with the attributes of motivation. This study underscores the significance of different attributes of motivation which needs to be considered while framing administrative strategies and policy guidelines by authorities. Copyright © 2018 John Wiley & Sons, Ltd.

  7. Growth perturbations in a phenotype with rapid fetal growth preceding preterm labor and term birth.

    PubMed

    Lampl, Michelle; Kusanovic, Juan Pedro; Erez, Offer; Gotsch, Francesca; Espinoza, Jimmy; Goncalves, Luis; Lee, Wesley; Gomez, Ricardo; Nien, Jyh Kae; Frongillo, Edward A; Romero, Roberto

    2009-01-01

    The variability in fetal growth rates and gestation duration in humans is not well understood. Of interest are women presenting with an episode of preterm labor and subsequently delivering a term neonate, who is small relative to peers of similar gestational age. To further understand these relationships, fetal growth patterns predating an episode of preterm labor were investigated. Retrospective analysis of fetal biometry assessed by serial ultrasound in a prospectively studied sample of pregnancies in Santiago, Chile, tested the hypothesis that fetal growth patterns among uncomplicated pregnancies (n = 3,706) and those with an episode of preterm labor followed by term delivery (n = 184) were identical across the time intervals 16-22 weeks, 22-28 weeks, and 28-34 weeks in a multilevel mixed-effects regression. The hypothesis was not supported. Fetal weight growth rate was faster from 16 weeks among pregnancies with an episode of preterm labor (P < 0.05), declined across midgestation (22-28 weeks, P < 0.05), and rebounded between 28 and 34 weeks (P = 0.06). This was associated with perturbations in abdominal circumference growth and proportionately larger biparietal diameter from 22 gestational weeks (P = 0.03), greater femur (P = 0.01), biparietal diameter (P = 0.001) and head circumference (P = 0.02) dimensions relative to abdominal circumference across midgestation (22-28 weeks), followed by proportionately smaller femur diaphyseal length (P = 0.02) and biparietal diameter (P = 0.03) subsequently. A distinctive rapid growth phenotype characterized fetal growth preceding an episode of preterm labor among this sample of term-delivered neonates. Perturbations in abdominal circumference growth and patterns of proportionality suggest an altered growth strategy pre-dating the preterm labor episode.

  8. Body size at birth and blood pressure among children in developing countries.

    PubMed

    Law, C M; Egger, P; Dada, O; Delgado, H; Kylberg, E; Lavin, P; Tang, G H; von Hertzen, H; Shiell, A W; Barker, D J

    2001-02-01

    Studies in developed countries have shown that reduced fetal growth is related to raised blood pressure in childhood and adult life. Little is known about this association in developing countries, where fetal growth retardation is common. In 1994-1995, we measured blood pressure in 1570 3-6-year-old children living in China, Guatemala, Chile, Nigeria and Sweden. We related their blood pressure to patterns of fetal growth, as measured by body proportions at birth. The children were all born after 37 weeks gestation and weighed more than 2.5 kg at birth. In each country, blood pressure was positively related to the child's current weight. After adjusting for this and gender, systolic pressure was inversely related to size at birth in all countries except Nigeria. In Chile, China and Guatemala, children who were proportionately small at birth had raised systolic pressure. For example, in Chile, systolic pressure adjusted for current weight increased by 4.9 mmHg (95% CI : 2.1, 7.7) for every kilogram decrease in birthweight, by 1 mmHg (95% CI : 0.4, 1.6) for every centimetre decrease in birth length, and by 1.3 mmHg (95% CI : 0.4, 2.2) for every centimetre decrease in head circumference at birth. In Sweden, systolic pressure was higher in children who were disproportionately small, that is thin, at birth. Systolic pressure increased by 0.3 mmHg (95% CI : 0.0, 0.6) for every unit (kg/m3) decrease in ponderal index at birth. These associations were independent of the duration of gestation. Raised blood pressure among children in three samples from China, Central and South America is related to proportionate reduction in body size at birth, which results from reduced growth throughout gestation. The relation between fetal growth and blood pressure may be different in African populations. Proportionately reduced fetal growth is the prevalent pattern of fetal growth retardation in developing countries, and is associated with chronic undernutrition among women. Improvement in the nutrition and health of girls and young women may be important in preventing cardiovascular disease in developing countries.

  9. When there are no good choices: illuminating the borderland between proportionate palliative sedation and palliative sedation to unconsciousness.

    PubMed

    Reid, Thomas T; Demme, Richard A; Quill, Timothy E

    2011-01-01

    Despite state-of-the-art palliative care, some patients will require proportionate palliative sedation as a last-resort option to relieve intolerable suffering at the end of life. In this practice, progressively increasing amounts of sedation are provided until the target suffering is sufficiently relieved. Uncertainty and debate arise when this practice approaches palliative sedation to unconsciousness (PSU), especially when unconsciousness is specifically intended or when the target symptoms are more existential than physical. We constructed a case series designed to highlight some of the common approaches and challenges associated with PSU and the more aggressive end of the spectrum of proportionate palliative sedation as retrospectively identified by palliative care consultants over the past 5 years from a busy inpatient palliative care service at a tertiary medical center in Rochester (NY, USA). Ten cases were identified as challenging by the palliative care attendings, of which four were selected for presentation for illustrative purposes because they touched on central issues including loss of capacity, the role of existential suffering, the complexity of clinical intention, the role of an institutional policy and use of anesthetics as sedative agents. Two other cases were selected focusing on responses to two special situations: a request for PSU that was rejected; and anticipatory planning for total sedation in the future. Although relatively rare, PSU and more aggressive end-of-the-spectrum proportionate palliative sedation represent responses to some of the most challenging cases faced by palliative care clinicians. These complex cases clearly require open communication and collaboration among caregivers, patients and family. Knowing how to identify these circumstances, and how to approach these interventions of last resort are critical skills for practitioners who take care of patients at the end of life.

  10. Occupational lung cancer in US women, 1984-1998.

    PubMed

    Robinson, Cynthia F; Sullivan, Patricia A; Li, Jia; Walker, James T

    2011-02-01

    Lung cancer is the leading cause of cancer death in US women, accounting for 72,130 deaths in 2006. In addition to smoking cessation, further reduction of the burden of lung cancer mortality can be made by preventing exposure to occupational lung carcinogens. Data for occupational exposures and health outcomes of US working women are limited. Population-based mortality data for 4,570,711 women who died between 1984 and 1998 in 27 US States were used to evaluate lung cancer proportionate mortality over time by the usual occupation and industry reported on death certificates. Lung cancer proportionate mortality ratios were adjusted for smoking, using data from the National Health Interview Survey (NHIS) and the American Cancer Society's Cancer Prevention Study II. Analyses revealed that 194,382 white, 18,225 Black and 1,515 Hispanic women died 1984-1998 with lung cancer reported as the underlying cause of death. Following adjustment for smoking, significant excess proportionate lung cancer mortality was observed among US women working in the US manufacturing; transportation; retail trade; agriculture, forestry, and fishing; and nursing/personal care industries. Women employed in precision production, technical, managerial, professional specialty, and administrative occupations experienced some of the highest significantly excess proportionate lung cancer mortality during 1984-1998. The results of our study point to significantly elevated risks for lung cancer after adjustment for smoking among women in several occupations and industries. Because 6-17% of lung cancer in US males is attributable to known exposures to occupational carcinogens, and since synergistic interactions between cigarette smoke and other occupational lung carcinogens have been noted, it is important to continue research into the effects of occupational exposures on working men and women. Copyright © 2010 Wiley-Liss, Inc.

  11. Ethical decision-making and professional behaviour among nurses: a correlational study.

    PubMed

    Cerit, Birgül; Dinç, Leyla

    2013-03-01

    This study examined the relationship between nurses' ethical decision-making levels and their professional behaviours. Data were collected from 225 nurses who were recruited from university hospitals in Ankara using proportionate sampling. Data were analysed using descriptive statistics and Pearson correlations. Most of the nurses were familiar with ethical dilemmas in nursing practice. The Nursing Principled Thinking level was above average, while the Practical Consideration level was average. Nurses' professionalism level was low. There was a positive but weak correlation between professional behaviours of the nurses and their ethical decision-making levels. Increasing nurses' professionalism level can provide a positive contribution to the ethical decision-making level.

  12. The sampling characteristics of electivity indices.

    PubMed

    Lechowicz, Martin J

    1982-01-01

    Electivity indices measure the utilization of food types (r) in relation to their abundance or availability in the environment (p). Foods that constitute a larger proportion of the diet than of the available foods are considered preferred; conversely those proportionately underrepresented in the diet are avoided. A food is eaten at random if its proportion in the diet equals its proportion in the environment. A family of electivity indices stemming from Ivlev's (1961) classic monograph exist and differ only in the particular algorithm used to calculate electivity from r and p.For each available index I graphed the values of electivity as contours for all combinations of r and p. These graphs are compared to illustrate the strengths and weaknesses of each index on the basis of the following criteria: 1) the value of the index when r=p for a food, 2) the symmetry of the electivity value as feeding deviates from random, 3) the possible range of index values, 4) the linearity of changes in electivity over the full range of r and p, 5) the sensitivity of the index to sampling errors, 6) the statistical testability of the electivity, and 7) the stability of the electivity value for a food type that changes relative abundance or occurs in combination with different food types. No one index ideally satisfies all the criteria.The host preferences of gypsy moth, Lymantria dispar, feeding on tree foliage in an undisturbed deciduous forest in southwestern Quebec, Canada were used to compare the available indices: Ivlev's electivity, E; Ivlev's forage ratio, E'; Jacob's modified electivity, D; Jacob's modified forage ratio, log Q; Chesson's alpha; Strauss' linear index, L; and Vanderploeg and Scavia's relativized electivity, E * . The electivity values calculated by each index differ one from another; host trees shown as preferred by one index will frequently appear avoided according to an alternative index. The rank order electivities for the 19 available host trees, however, are remarkably similar for all but Strauss' linear index, L. Populus grandidentata, Quercus rubra, Ostrya virginiana, and Amelanchier were the most preferred host trees in the sampled forest; Prunus serotina, Acer pensylvanicum, A. rubrum, Betula lutea, and Fraxinus americana were most avoided. The use of Vanderploeg and Scavia's E * index is recommended.

  13. Alcohol Consumption Practices among Married Women of Reproductive Age in Nepal: A Population Based Household Survey

    PubMed Central

    Thapa, Narbada; Aryal, Krishna Kumar; Puri, Rupendra; Shrestha, Saraswoti; Shrestha, Sheela; Thapa, Pukar; Mehata, Suresh; Thapa, Pushpa; Banjara, Megha Raj; Stray-Pedersen, Babill

    2016-01-01

    Background Alcohol chemically known as ethanol, causes several health, economic and social consequences across the world. Literatures suggest potential harm of alcohol drinking by pregnant women especially to the fetus and the mother. Despite anumber of significant public health problems related to alcohol consumption, this area has been ignored in Nepal and information at the national level is limited. Thus this study aimed at finding the prevalence of alcohol consumption among married women of reproductive age. Methods A nationally representative household survey was carried out from April to August 2013 by taking 16 districts across all 15 eco administrative regions. From the selected districts, 86 village development committees and 14 municipalities were selected as primary sampling units using probability proportionate to size, followed by random selection of 3 wards from each primary sampling unit. Finally, 30 households within each ward were selected using systematic random sampling, and one married women of reproductive age from each household. A total of 9000 married women of reproductive age were interviewed using a semi-structured questionnaire, on alcohol consumption practices including environmental factors and socio demographic characteristics and were included in the analysis. Results National prevalence of alcohol consumption ever among married women of reproductive age was 24.7% (95% CI:21.7–28.0), last 12 months 17.9% (95% CI:15.3–20.7) and last 30 days (current drinking) 11.8% (95% CI:9.8–14.1). There was substantial variation among the districts ranging from 2% to 60%. Multivariable analysis suggests women with no education or within formal education, dalit and janajatis ethnicity, whose husbands drink alcohol, who brew alcohol at home and women from mountains were significantly at higher risk of consuming alcohol. Among the women who drank alcohol in last 12 months, a substantial proportion of them drank home brewed alcoholic beverages (95.9%, 95% CI:94.3–97.4). Conclusion Alcohol consumption was common practice among married women of reproductive age in Nepal with variation among the subgroups of population. Thus, further investigation and behavior change communication interventions to reduce alcohol consumption especially among the women with higher risk of drinking is essential. PMID:27035722

  14. Visual impairment and blindness in Hungary.

    PubMed

    Szabó, Dorottya; Sándor, Gábor László; Tóth, Gábor; Pék, Anita; Lukács, Regina; Szalai, Irén; Tóth, Georgina Zsófia; Papp, András; Nagy, Zoltán Zsolt; Limburg, Hans; Németh, János

    2018-03-01

    The aim of this study was to estimate the prevalence and causes of blindness, severe visual impairment (SVI), moderate visual impairment (MVI), and early visual impairment (EVI) and its causes in an established market economy of Europe. A cross-sectional population-based survey. A sample size of 3675 was calculated using the standard Rapid Assessment of Avoidable Blindness (RAAB) software in Hungary. A total of 105 clusters of 35 people aged 50 years or older were randomly selected with probability proportionate to size by the Hungarian Central Statistical Office. Households within the clusters were selected using compact segment sampling. Visual acuity (VA) was assessed with a Snellen tumbling E-chart with or without a pinhole in the households. The adjusted prevalences of bilateral blindness, SVI, MVI and EVI were 0.9% (95% CI: 0.6-1.2), 0.5% (95% CI: 0.2-0.7), 5.1% (95% CI: 4.3-5.9) and 6.9% (95% CI: 5.9-7.9), respectively. The major causes of blindness in Hungary were age-related macular degeneration (AMD; 27.3%) and other posterior segment diseases (27.3%), cataract (21.2%) and glaucoma (12.1%). Cataract was the main cause of SVI, MVI and EVI. Cataract surgical coverage (CSC) was 90.7%. Of all bilateral blindness in Hungary, 45.5% was considered avoidable. This study proved that RAAB methodology can be successfully conducted in industrialized countries, which often lack reliable epidemiologic data. The prevalence of blindness was relatively low, with AMD and other posterior segment diseases being the leading causes, and cataract is still a significant cause of visual impairment. © 2017 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

  15. Secondhand smoke in public places: can Bangalore metropolitan transport corporation be a role model for effective implementation of Cigarette and Other Tobacco Products Act, 2003?

    PubMed

    Nayak, N S; Annigeri, V B; Revankar, D R; Kenchaigol, S

    2010-07-01

    The Indian government enacted 'The cigarettes and other tobacco products act, 2003' (COTPA), which prohibits smoking in public places. To validate the efficacy of the Act of 2003, enacted by the Government of India, to prevent secondhand smoking in public places. The study is based on a non-random sample survey of 2,600 bus passengers carried out in the premises of three mega public road transport organizations in Karnataka state, India, in June 2007. The information was gathered through administration of structured schedules. A sample of 1,000 each for the terminus of Bangalore Metropolitan Transport Corporation (BMTC) and Karnataka State Road Transport Corporation (KSRTC) in Bangalore and, 600 for North West Karnataka Road Transport Corporation (NWKRTC) in Hubli-Dharwad city was distributed proportionately according to the number of platforms in each terminus. Simple Averages. There is some reduction in smoking in general as perceived by 69% of the passengers as compared to the scenario a year before the enactment of COTPA. The observed smoking is lower in the bus premises of BMTC where there is strict regulation, and higher in the bus premises of NWKRTC, which has not taken any regulatory measures. Knowing smoking is banned in public places can itself create awareness depending on the coverage extended by media and implementing an agency to reach the public. The implementation of an act depends on the willingness of stakeholders to act upon it. The implementation of COTPA as done by BMTC could well become a role model for replication elsewhere, if BMTC can strive harder to accomplish a 100% smoke-free zone.

  16. On geological interpretations of crystal size distributions: Constant vs. proportionate growth

    USGS Publications Warehouse

    Eberl, D.D.; Kile, D.E.; Drits, V.A.

    2002-01-01

    Geological interpretations of crystal size distributions (CSDs) depend on understanding the crystal growth laws that generated the distributions. Most descriptions of crystal growth, including a population-balance modeling equation that is widely used in petrology, assume that crystal growth rates at any particular time are identical for all crystals, and, therefore, independent of crystal size. This type of growth under constant conditions can be modeled by adding a constant length to the diameter of each crystal for each time step. This growth equation is unlikely to be correct for most mineral systems because it neither generates nor maintains the shapes of lognormal CSDs, which are among the most common types of CSDs observed in rocks. In an alternative approach, size-dependent (proportionate) growth is modeled approximately by multiplying the size of each crystal by a factor, an operation that maintains CSD shape and variance, and which is in accord with calcite growth experiments. The latter growth law can be obtained during supply controlled growth using a modified version of the Law of Proportionate Effect (LPE), an equation that simulates the reaction path followed by a CSD shape as mean size increases.

  17. Selection methods regulate evolution of cooperation in digital evolution

    PubMed Central

    Lichocki, Paweł; Floreano, Dario; Keller, Laurent

    2014-01-01

    A key, yet often neglected, component of digital evolution and evolutionary models is the ‘selection method’ which assigns fitness (number of offspring) to individuals based on their performance scores (efficiency in performing tasks). Here, we study with formal analysis and numerical experiments the evolution of cooperation under the five most common selection methods (proportionate, rank, truncation-proportionate, truncation-uniform and tournament). We consider related individuals engaging in a Prisoner's Dilemma game where individuals can either cooperate or defect. A cooperator pays a cost, whereas its partner receives a benefit, which affect their performance scores. These performance scores are translated into fitness by one of the five selection methods. We show that cooperation is positively associated with the relatedness between individuals under all selection methods. By contrast, the change in the performance benefit of cooperation affects the populations’ average level of cooperation only under the proportionate methods. We also demonstrate that the truncation and tournament methods may introduce negative frequency-dependence and lead to the evolution of polymorphic populations. Using the example of the evolution of cooperation, we show that the choice of selection method, though it is often marginalized, can considerably affect the evolutionary dynamics. PMID:24152811

  18. Pulse-Echo Ultrasonic Imaging Method for Eliminating Sample Thickness Variation Effects

    NASA Technical Reports Server (NTRS)

    Roth, Don J. (Inventor)

    1997-01-01

    A pulse-echo, immersion method for ultrasonic evaluation of a material which accounts for and eliminates nonlevelness in the equipment set-up and sample thickness variation effects employs a single transducer and automatic scanning and digital imaging to obtain an image of a property of the material, such as pore fraction. The nonlevelness and thickness variation effects are accounted for by pre-scan adjustments of the time window to insure that the echoes received at each scan point are gated in the center of the window. This information is input into the scan file so that, during the automatic scanning for the material evaluation, each received echo is centered in its time window. A cross-correlation function calculates the velocity at each scan point, which is then proportionalized to a color or grey scale and displayed on a video screen.

  19. Corridor Use Predicted from Behaviors at Habitat Boundaries.

    PubMed

    Haddad, Nick M

    1999-02-01

    Through empirical studies and simulation, I demonstrate how simple behaviors can be used in lieu of detailed dispersal studies to predict the effects of corridors on interpatch movements. Movement paths of three butterfly species were measured in large (1.64 ha) experimental patches of open habitat, some of which were connected by corridors. Butterflies that "reflected" off boundaries between open patches and the surrounding forest also emigrated from patches through corridors at rates higher than expected from random movement. This was observed for two open-habitat species, Eurema nicippe and Phoebis sennae; however, edges and corridors had no effect on a habitat generalist, Papilio troilus. Behaviorally based simulation models, which departed from correlated random walks only at habitat boundaries, predicted that corridors increase interpatch movement rates of both open-habitat species. Models also predicted that corridors have proportionately greater effects as corridor width increases, that movement rates increase before leveling off as corridor width increases, and that corridor effects decrease as patch size increases. This study suggests that corridors direct movements of habitat-restricted species and that local behaviors may be used to predict the conservation potential of corridors in fragmented landscapes.

  20. The Nakuru posterior segment eye disease study: methods and prevalence of blindness and visual impairment in Nakuru, Kenya.

    PubMed

    Mathenge, Wanjiku; Bastawrous, Andrew; Foster, Allen; Kuper, Hannah

    2012-10-01

    To estimate the prevalence of blindness and visual impairment (VI) in adults aged ≥50 years in the Nakuru district of Kenya and to identify sociodemographic risk factors for these conditions. We also sought to validate the Rapid Assessment of Avoidable Blindness (RAAB) methodology. There were 5010 subjects enumerated for this study. Of these, 4414 participants underwent examination, for a response rate of 88.1%. Cross-sectional, population-based survey. Cluster random samplings with probability proportionate to size procedures were used to select a representative cross-sectional sample of adults aged ≥50 years. Each participant was interviewed, had distance visual acuity (VA) measured with reduced logarithm of the minimal angle of resolution tumbling-E chart, underwent autorefraction, and thereby had measurements of presenting, uncorrected, and best-corrected VA. All participants, regardless of vision, underwent detailed ophthalmic examinations including slit-lamp assessment and dilated retinal photographs. Visual acuity of <6/12. A representative sample of 4414 adults were enumerated (response rate, 88.1%). The prevalence of blindness (VA < 3/60 in better eye) was 1.6% (95% confidence interval [CI], 1.2-2.1%) and of VI, 0.4% (95% CI, 0.3-0.7%); 8.1% (95% CI, 7.2-9.2%); and 5.1% (95% CI, 4.3-6.1%) were severely (<6/60-3/60), moderately (<6/18-6/60), or mildly (<6/12-6/18) visually impaired, respectively. Being male, having less education, having Kalenjin tribal origin, and being ≥80 years old were associated with increased blindness prevalence. Prevalence estimates were comparable to a RAAB performed in the same area 2 years earlier. This survey provides reliable estimates of blindness and VI prevalence in Nakuru. Older age and tribal origin were identified as predictors of these conditions. This survey validates the use of RAAB as a method of estimating blindness and VI prevalence. Copyright © 2012 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

  1. Mujer Mas Segura (Safer Women): a combination prevention intervention to reduce sexual and injection risks among female sex workers who inject drugs.

    PubMed

    Vera, Alicia; Abramovitz, Daniela; Lozada, Remedios; Martinez, Gustavo; Rangel, M Gudelia; Staines, Hugo; Patterson, Thomas L; Strathdee, Steffanie A

    2012-08-14

    Female sex workers who inject drugs (FSW-IDUs) are at risk of acquiring HIV, sexually transmitted infections (STI) and blood-borne infections through unprotected sex and sharing injection equipment. We conducted a 2×2 factorial randomized controlled trial to evaluate combination interventions to simultaneously reduce sexual and injection risks among FSW-IDUs in Tijuana and Ciudad Juarez, Mexico. FSW-IDUs ≥18 years reporting sharing injection equipment and unprotected sex with clients within the last month were randomized to one of four conditions based on an a priori randomization schedule, blinding interviewer/counselors to assignment. Due to the extreme vulnerability of this population, we did not include a control group that would deny some women access to preventive information. All women received similar information regardless of group allocation; the difference was in the way the information was delivered and the extent to which women had an interactive role. Each condition was a single 60-minute session, including either an interactive or didactic version of an injection risk intervention and sexual risk intervention. Women underwent interviewer-administered surveys and testing for HIV, syphilis, gonorrhea, Chlamydia, and Trichomonas at baseline and quarterly for 12 months. Combined HIV/STI incidence will be the primary outcome. Secondary outcomes are proportionate reductions in sharing of injection equipment and unprotected sex with clients. Of 1,132 women, 548 (48.4%) were excluded (88.9% were ineligible; 11.1% refused to participate or did not return); 584 eligible women enrolled (284 in Tijuana; 300 in Ciudad Juarez). All 584 participants completed the baseline interview, provided biological samples and were randomized to one of the four groups. During follow-up, 17 participants (2.9%) were lost to follow-up, of whom 10 (58.8%) had died, leaving 567 participants for analysis. This study appears to be the first intervention to attempt to simultaneously reduce injection and sexual risk behaviors among FSW-IDUs. The factorial design will permit analysis to determine whether the combination of the two interactive interventions and/or its respective components are effective in reducing injection and/or sexual risks, which will have direct, tangible policy implications for Mexico and potentially other resource-poor countries. NCT00840658.

  2. Mujer Mas Segura (Safer Women): a combination prevention intervention to reduce sexual and injection risks among female sex workers who inject drugs

    PubMed Central

    2012-01-01

    Background Female sex workers who inject drugs (FSW-IDUs) are at risk of acquiring HIV, sexually transmitted infections (STI) and blood-borne infections through unprotected sex and sharing injection equipment. We conducted a 2×2 factorial randomized controlled trial to evaluate combination interventions to simultaneously reduce sexual and injection risks among FSW-IDUs in Tijuana and Ciudad Juarez, Mexico. Methods/design FSW-IDUs ≥18 years reporting sharing injection equipment and unprotected sex with clients within the last month were randomized to one of four conditions based on an a priori randomization schedule, blinding interviewer/counselors to assignment. Due to the extreme vulnerability of this population, we did not include a control group that would deny some women access to preventive information. All women received similar information regardless of group allocation; the difference was in the way the information was delivered and the extent to which women had an interactive role. Each condition was a single 60-minute session, including either an interactive or didactic version of an injection risk intervention and sexual risk intervention. Women underwent interviewer-administered surveys and testing for HIV, syphilis, gonorrhea, Chlamydia, and Trichomonas at baseline and quarterly for 12 months. Combined HIV/STI incidence will be the primary outcome. Secondary outcomes are proportionate reductions in sharing of injection equipment and unprotected sex with clients. Discussion Of 1,132 women, 548 (48.4%) were excluded (88.9% were ineligible; 11.1% refused to participate or did not return); 584 eligible women enrolled (284 in Tijuana; 300 in Ciudad Juarez). All 584 participants completed the baseline interview, provided biological samples and were randomized to one of the four groups. During follow-up, 17 participants (2.9%) were lost to follow-up, of whom 10 (58.8%) had died, leaving 567 participants for analysis. This study appears to be the first intervention to attempt to simultaneously reduce injection and sexual risk behaviors among FSW-IDUs. The factorial design will permit analysis to determine whether the combination of the two interactive interventions and/or its respective components are effective in reducing injection and/or sexual risks, which will have direct, tangible policy implications for Mexico and potentially other resource-poor countries. Trial registration NCT00840658 PMID:22891807

  3. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Madronich, Sasha; Kleinman, Larry; Conley, Andrew

    Gas-to-particle partitioning of organic aerosols (OA) is represented in most models by Raoult’s law, and depends on the existing mass of particles into which organic gases can dissolve. This raises the possibility of non-linear response of particle-phase OA to the emissions of precursor volatile organic compounds (VOCs) that contribute to this partitioning mass. Implications for air quality management are evident: A strong non-linear dependence would suggest that reductions in VOC emission would have a more-than-proportionate benefit in lowering ambient OA concentrations. Chamber measurements on simple VOC mixtures generally confirm the non-linear scaling between OA and VOCs, usually stated as amore » mass-dependence of the measured OA yields. However, for realistic ambient conditions including urban settings, no single component dominates the composition of the organic particles, and deviations from linearity are presumed to be small. Here we re-examine the linearity question using volatility spectra from several sources: (1) chamber studies of selected aerosols, (2) volatility inferred for aerosols sampled in two megacities, Mexico City and Paris, and (3) an explicit chemistry model (GECKO-A). These few available volatility distributions suggest that urban OA may be only slightly super-linear, with most values of the sensitivity exponent in the range 1.1-1.3, also substantially lower than seen in chambers for some specific aerosols. Furthermore, the rather low values suggest that OA concentrations in megacities are not an inevitable convergence of non-linear effects, but can be addressed (much like in smaller urban areas) by proportionate reductions in emissions.« less

  4. Health Care Waste Management Practice in Health Care Institutions of Nepal.

    PubMed

    Joshi, H D; Acharya, T; Ayer, R; Dhakal, P; Karki, K B; Dhimal, M

    2017-01-01

    Medical waste is considered as a major public health hazard. In a developing country like Nepal, there is much concern about the management practice of medical waste. This study aimed to assess Health Care Waste Management practice among Health Care Institutions in Nepal. A cross sectional study was carried out between July 2012 to June 2013 in 62 different Health Care Institutions, selected from stratified proportionate random sampling technique from all administrative regions of Nepal. A structured questionnaire and observation checklist were used for data collection. The waste generation rate is found significantly correlated with bed capacity, patient flow rate and annual budget spent in the hospital. It is found significantly higher in Teaching hospital than other Health Care Institutions of Nepal. An average of 3.3 kg/day/patient of medical waste (2.0 kg/day/patient non-hazardous and 1.0 kg/day/patient hazardous waste) was generated during the study period. Further, it was found that most of the Health care wastes were not disinfected before transportation to waste disposal sites. Very limited number of Health Care Institutions had conducted Environmental Assessment. Similarly, some of the Health Care Institutions had not followed Health care waste management guideline 2009 of Nepal Government. We found poor compliance of medical waste management practice as per existing legislation of Government of Nepal. Hence, additional effort is needed for improvement of Health care waste management practice at Health Care Institutions of Nepal.

  5. prevalence and causes of blindness and low vision revisited after 5 years of eye care in Timor-Leste.

    PubMed

    Ramke, Jacqueline; Brian, Garry; Naduvilath, Thomas; Lee, Lucy; Qoqonokana, Mundi Qalo

    2012-04-01

    To estimate the 2010 prevalence and causes of blindness and low vision among Timor-Leste adults aged ≥40 years, and compare these to the results of a survey conducted 5 years previously. A population-based cross-sectional survey used multistage cluster random sampling proportionate to size to identify 50 clusters of 45 people each. Cause of vision loss was determined for each eye with presenting visual acuity worse than 6/18. A participation rate of 89.5% (n = 2014) was achieved. The gender-age-domicile adjusted prevalence was 7.7% (95% confidence interval [CI] 6.5, 8.8) for 6/60, and 3.6% (95% CI 2.7, 4.4) for 3/60 blindness (better eye presenting vision worse than 6/60 and 3/60, respectively) among Timorese aged ≥40 years. Cataract caused most blindness (69.3% at 6/60). The population prevalence of low vision (better eye presenting vision of 6/60 or better, but worse than 6/18) was 13.6% (95%CI 12.1, 15.1), most caused by uncorrected refractive error (57.4%) or cataract (39.5%). The prevalence and causes of blindness were unchanged compared with 5 years earlier, but low vision was less common. Unusually for a developing country, Timor-Leste has initiated a cycle of evidence-based eye care in which, although with limitations, population data are periodically available for monitoring and planning.

  6. Regulatory decision-making under uncertainty: are costs proportionate to benefits when restricting dangerous chemicals on European markets?

    PubMed

    Brouwer, Roy; Cauchi, Jonathan; Verhoeven, Julia

    2014-04-01

    Since 2007 regulation 1907/2006/EC concerning the Registration, Evaluation, Authorization and Restriction of Chemicals (REACH) is in force in Europe to reduce the adverse effects of hazardous chemical substances on human health and the environment. Implementation of the regulation by the European Chemicals Agency (ECHA) is supported by a Socio-Economic Analysis (SEA) Committee, consisting of European experts who help prepare ECHA's opinion on proposals for either restricting or authorizing dangerous substances. This paper presents the outcomes of the SEA underlying the first restriction proposals. Member states proposing a restriction have to show that it will reduce the risks to an acceptable level at a cost which is proportionate to the avoided risk. What is considered proportionate is not clearly defined in REACH. The opinion making process is characterized by many uncertainties: the expert group had no previous experiences to fall back on and limited information about the expected costs and benefits of the proposed restrictions. The study provides insight into expert opinions on environmental and health risks under uncertainty in the specific context of REACH. Particular attention is paid to the confidence experts place on the estimated socio-economic benefits of the avoided risks compared to the estimated compliance costs. Copyright © 2014 Elsevier Inc. All rights reserved.

  7. Proportionate mortality of Italian soccer players: is amyotrophic lateral sclerosis an occupational disease?

    PubMed

    Belli, Stefano; Vanacore, Nicola

    2005-01-01

    The objective of the study is to investigate the mortality experience of Italian soccer players and to discuss the findings in the light of possible long term effects of doping. Standardized proportionate mortality ratio (SPMR) and standardized proportionate cancer mortality ratio (SPCMR) were computed for 350 deceased subjects deriving from a list of about 24,000 active Italian soccer players from 1960 to 1996 in the three top leagues (A, B and C). When considering SPMRs, there is a substantial adherence of observed to expected mortality, with the only exception of mortality for diseases of the nervous system (13 obs. vs. 6 exp.) mainly explained by an excess of amyotrophic lateral sclerosis (8 obs. vs 0.69 exp.). As far as SPCMRs are concerned, some digestive cancers (namely: colon cancer, liver cancer and pancreas cancer) show a doubled risk. A high risk for amyotrophic lateral sclerosis is observed among Italian soccer players. Epidemiological data on association between sport and Amyotrophic Lateral Sclerosis (ALS) are contrasting. On the basis of the overall available evidence we suggest a possible connection between dietary supplements or drugs used to enhance sporting performance and ALS pathogenesis. Further epidemiological studies are needed to confirm these specific mortality risks among soccer players.

  8. Pulse-echo ultrasonic imaging method for eliminating sample thickness variation effects

    NASA Technical Reports Server (NTRS)

    Roth, Don J. (Inventor)

    1995-01-01

    A pulse-echo, immersion method for ultrasonic evaluation of a material is discussed. It accounts for and eliminates nonlevelness in the equipment set-up and sample thickness variation effects employs a single transducer, automatic scanning and digital imaging to obtain an image of a property of the material, such as pore fraction. The nonlevelness and thickness variation effects are accounted for by pre-scan adjusments of the time window to insure that the echoes received at each scan point are gated in the center of the window. This information is input into the scan file so that, during the automatic scanning for the material evaluation, each received echo is centered in its time window. A cross-correlation function calculates the velocity at each scan point, which is then proportionalized to a color or grey scale and displayed on a video screen.

  9. The mean fibre area of the semitendinosus, diaphragm and pectoralis transversus muscles in differing types of horse and dog.

    PubMed Central

    Gunn, H M

    1978-01-01

    The mean fibre areas of samples from m. semitendinosus, m. diaphragma and m. pectoralis transversus of thoroughbred horses and greyhounds have been compared with those in similar samples from other members of their species. Athletes (greyhounds and thoroughbreds) have larger fibres in the semitendinosus and diaphragm than their fellows. However, the mean area of pectoralis transversus is similar in the two types of animal within each species. During growth the mean fibre areas increase to a greater extent in athletes than in non-athletes. Detraining adult greyhounds for a period of one year did not signficantly alter the fibre area; nor were any sex differences detected. Although the mean fibre area of corresponding muscles is significantly larger in horses than in dogs, the difference is proportionately less than that of their live weights. PMID:721700

  10. Prevalence and concentration of Salmonella on raw shelled peanuts in the United States.

    PubMed

    Calhoun, Stephen; Post, Laurie; Warren, Benjamin; Thompson, Sterling; Bontempo, Ann Rogers

    2013-04-01

    Recalls and/or outbreaks associated with Salmonella contamination in peanut-containing products were reported over the past several years. There are very limited data available on the prevalence and concentration of Salmonella on raw shelled peanuts in the United States. The objectives of this study were to estimate the prevalence of Salmonella on raw shelled peanuts in the United States and to estimate that concentration of Salmonella. Samples of Runner- and Virginia-type raw shelled peanuts from the 2008, 2009, and 2010 crop years were proportionately sampled from each growing region, based on 2007 production volume. Of 944 raw shelled peanut samples (375 g each), 22 (2.33%) were positive for Salmonella by the VIDAS Salmonella assay. Salmonella serovars identified in this study included Agona, Anatum, Braenderup, Dessau, Hartford, Meleagridis, Muenchen, Rodepoort, Tennessee, and Tornow. The concentration levels of Salmonella in positive samples, as determined by a most-probable-number assay, were <0.03 to 2.4 MPN/g. These data will be useful when designing and validating processes for the reduction or elimination of Salmonella in peanuts and/or peanut-containing products.

  11. Households across all income quintiles, especially the poorest, increased animal source food expenditures substantially during recent Peruvian economic growth.

    PubMed

    Humphries, Debbie L; Behrman, Jere R; Crookston, Benjamin T; Dearden, Kirk A; Schott, Whitney; Penny, Mary E

    2014-01-01

    Relative to plant-based foods, animal source foods (ASFs) are richer in accessible protein, iron, zinc, calcium, vitamin B-12 and other nutrients. Because of their nutritional value, particularly for childhood growth and nutrition, it is important to identify factors influencing ASF consumption, especially for poorer households that generally consume less ASFs. To estimate differential responsiveness of ASF consumption to changes in total household expenditures for households with different expenditures in a middle-income country with substantial recent income increases. The Peruvian Young Lives household panel (n = 1750) from 2002, 2006 and 2009 was used to characterize patterns of ASF expenditures. Multivariate models with controls for unobserved household fixed effects and common secular trends were used to examine nonlinear relationships between changes in household expenditures and in ASF expenditures. Households with lower total expenditures dedicated greater percentages of expenditures to food (58.4% vs.17.9% in 2002 and 24.2% vs. 21.5% in 2009 for lowest and highest quintiles respectively) and lower percentages of food expenditures to ASF (22.8% vs. 33.9% in 2002 and 30.3% vs. 37.6% in 2009 for lowest and highest quintiles respectively). Average percentages of overall expenditures spent on food dropped from 47% to 23.2% between 2002 and 2009. Households in the lowest quintiles of expenditures showed greater increases in ASF expenditures relative to total consumption than households in the highest quintiles. Among ASF components, meat and poultry expenditures increased more than proportionately for households in the lowest quintiles, and eggs and fish expenditures increased less than proportionately for all households. Increases in household expenditures were associated with substantial increases in consumption of ASFs for households, particularly households with lower total expenditures. Increases in ASF expenditures for all but the top quintile of households were proportionately greater than increases in total food expenditures, and proportionately less than overall expenditures.

  12. Households across All Income Quintiles, Especially the Poorest, Increased Animal Source Food Expenditures Substantially during Recent Peruvian Economic Growth

    PubMed Central

    Humphries, Debbie L.; Behrman, Jere R.; Crookston, Benjamin T.; Dearden, Kirk A.; Schott, Whitney; Penny, Mary E.

    2014-01-01

    Background Relative to plant-based foods, animal source foods (ASFs) are richer in accessible protein, iron, zinc, calcium, vitamin B-12 and other nutrients. Because of their nutritional value, particularly for childhood growth and nutrition, it is important to identify factors influencing ASF consumption, especially for poorer households that generally consume less ASFs. Objective To estimate differential responsiveness of ASF consumption to changes in total household expenditures for households with different expenditures in a middle-income country with substantial recent income increases. Methods The Peruvian Young Lives household panel (n = 1750) from 2002, 2006 and 2009 was used to characterize patterns of ASF expenditures. Multivariate models with controls for unobserved household fixed effects and common secular trends were used to examine nonlinear relationships between changes in household expenditures and in ASF expenditures. Results Households with lower total expenditures dedicated greater percentages of expenditures to food (58.4% vs.17.9% in 2002 and 24.2% vs. 21.5% in 2009 for lowest and highest quintiles respectively) and lower percentages of food expenditures to ASF (22.8% vs. 33.9% in 2002 and 30.3% vs. 37.6% in 2009 for lowest and highest quintiles respectively). Average percentages of overall expenditures spent on food dropped from 47% to 23.2% between 2002 and 2009. Households in the lowest quintiles of expenditures showed greater increases in ASF expenditures relative to total consumption than households in the highest quintiles. Among ASF components, meat and poultry expenditures increased more than proportionately for households in the lowest quintiles, and eggs and fish expenditures increased less than proportionately for all households. Conclusions Increases in household expenditures were associated with substantial increases in consumption of ASFs for households, particularly households with lower total expenditures. Increases in ASF expenditures for all but the top quintile of households were proportionately greater than increases in total food expenditures, and proportionately less than overall expenditures. PMID:25372596

  13. Use of medications for erectile dysfunction in the United States, 1996 through 2001.

    PubMed

    Wysowski, Diane K; Swann, Joslyn

    2003-03-01

    We describe the use during 1996 through 2001 of the primary medications approved in the United States for treatment of erectile dysfunction, namely alprostadil injection and urethral suppository, and sildenafil. MATERIALS AND METHODS Two pharmaceutical research data bases, the National Prescription Audit Plus, and National Disease and Therapeutic Index, were accessed and analyzed. Ancillary data were obtained from 2 health plans. Increases in the number of dispensed prescriptions for alprostadil injection and urethral suppository marketed in 1995 and 1996, respectively, were reversed in 1998 by the marketing of sildenafil. From 1998 through 2001 the estimated number of prescriptions for sildenafil increased 1.87-fold or 87% from 7.5 million to 14 million, while those for alprostadil injection decreased 33% from 239,000 to 159,000 and those for alprostadil suppository decreased 67% from 400,000 to 132,000. Sildenafil was prescribed proportionately more frequently for younger men than alprostadil injection or suppository (p <0.0001). Compared with men for whom sildenafil was prescribed in 1998 those prescribed the drug in 2001 were younger (p <0.0001). Alprostadil injection and suppository were prescribed proportionately more frequently by urologists than sildenafil. Ancillary data from 2 health plans indicated a 173% increase in 1 plan and a 25% decrease in the other due to restrictions in sildenafil prescriptions from 1998 through 2001. Due to the marketing of sildenafil in 1998 through 2001 the use of 2 approved medications for erectile dysfunction, namely alprostadil injection and alprostadil urethral suppository, decreased, while the use of sildenafil increased. Sildenafil was prescribed proportionately more frequently for younger men than alprostadil injection or suppository. Alprostadil was prescribed proportionately more frequently by urologists than sildenafil, which was most commonly prescribed by family and general practitioners, and internists. The data indicate the wide adoption and use of sildenafil for erectile dysfunction.

  14. The use of information sources by faculty members of babol university of medical sciences: a case study from iran.

    PubMed

    Siamian, Hasan; Yaminfirooz, Moosa; Dehghan, Zahra; Shahrabi, Afsaneh

    2013-01-01

    This study seeks to determine the expertise, use, and satisfaction of faculty members of Babol University of Medical Sciences, using the provided online information services by the university. This study is descriptive and analytical survey and the information gathering was through the questionnaireand the samples, based on the random of Kerjesi and Morgan Table sample size determination that was selected through stratified sampling proportionately to the size of the departments which summed up to 155 of which 113 responded to the mailed questionnaire. The results of the study show that among the various data sources such as books, journals and internet, faculty members have more undemandingand convenient access to the Internet compared to other resources use, however, half of the information needs of faculty members, 57 (50.4 percent) are provided by the printed books;and the databases available to the University and used by faculty members are PubMed with 76.1% and Science direct with 53.1% and Iranmedex with 46.9%.Only 17% of faculty members have the absolute contentment of the Internet information services,and more than half of the respondents (58.4%) expressed the low speed of Internet service as their major reason for their dissatisfaction of the provided services. Use and Satisfaction of Internet-Based Information Services of Faculty Members. Using the Internet to provide the needed information with an index of 46%is a significant issue. The results of the study show that among the various data sources such as books, journals and internet, faculty members have more undemandingand convenient access to the Internet and their access to printed books was really hard and limited, although the internet was more convenient to acquire information, most of the information needs of faculty members are provided by the printed books based on what they expressed. The study showed that the use and acquaintance of the sample of the information databases is very lowand only a few of them have the full satisfaction of the provided Internet information services and the main foremost reason for this major dissatisfaction is the low-speed Internet services at the University.

  15. Study to develop educational products about the fear of new energy technologies. Phase II

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    DuPont, R.L.

    1985-01-31

    Fear of nuclear power was found in the study sample to be widespread and far more intense than fear of any other energy source. Fears were greatest of waste disposal and accidents, with fear of what is not known being especially common. Many fears appeared to be based on lack of information. Both general and specific fears of nuclear power were significantly reduced by reading an educational booklet. After reading this booklet study subjects reported less extreme views of nuclear power, seeing it to be more similar to other energy sources. This decline in fear of nuclear power did notmore » produce a proportionate increase in support for nuclear power as a source of electricity.« less

  16. Pioglitazone use and heart failure in patients with type 2 diabetes and preexisting cardiovascular disease: data from the PROactive study (PROactive 08).

    PubMed

    Erdmann, Erland; Charbonnel, Bernard; Wilcox, Robert G; Skene, Allan M; Massi-Benedetti, Massimo; Yates, John; Tan, Meng; Spanheimer, Robert; Standl, Eberhard; Dormandy, John A

    2007-11-01

    PROspective pioglitAzone Clinical Trial In macroVascular Events (PROactive) enrolled patients with type 2 diabetes and preexisting cardiovascular disease. These patients were at high risk for heart failure, so any therapeutic benefit could potentially be offset by risk of associated heart failure mortality. We analyzed the heart failure cases to assess the effects of treatment on morbidity and mortality after reports of serious heart failure. PROactive was an outcome study in 5,238 patients randomized to pioglitazone or placebo. Patients with New York Heart Association Class II-IV heart failure at screening were excluded. A serious adverse event of heart failure was defined as heart failure that required hospitalization or prolonged a hospitalization stay, was fatal or life threatening, or resulted in persistent significant disability or incapacity. Heart failure risk was evaluated by multivariate regression. More pioglitazone (5.7%) than placebo patients (4.1%) had a serious heart failure event during the study (P = 0.007). However, mortality due to heart failure was similar (25 of 2,605 [0.96%] for pioglitazone vs. 22 of 2,633 [0.84%] for placebo; P = 0.639). Among patients with a serious heart failure event, subsequent all-cause mortality was proportionately lower with pioglitazone (40 of 149 [26.8%] vs. 37 of 108 [34.3%] with placebo; P = 0.1338). Proportionately fewer pioglitazone patients with serious heart failure went on to have an event in the primary (47.7% with pioglitazone vs. 57.4% with placebo; P = 0.0593) or main secondary end point (34.9% with pioglitazone vs. 47.2% with placebo; P = 0.025). Although the incidence of serious heart failure was increased with pioglitazone versus placebo in the total PROactive population of patients with type 2 diabetes and macrovascular disease, subsequent mortality or morbidity was not increased in patients with serious heart failure.

  17. 42 CFR 7.4 - Schedule of charges.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... is available from the Division of Scientific Resources, Centers for Disease Control, 1600 Clifton..., and a proportionate share of management and administrative costs), and the cost of particular...

  18. 42 CFR 7.4 - Schedule of charges.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... is available from the Division of Scientific Resources, Centers for Disease Control, 1600 Clifton..., and a proportionate share of management and administrative costs), and the cost of particular...

  19. FDATMOS16 non-linear partitioning and organic volatility distributions in urban aerosols

    DOE PAGES

    Madronich, Sasha; Kleinman, Larry; Conley, Andrew; ...

    2015-12-17

    Gas-to-particle partitioning of organic aerosols (OA) is represented in most models by Raoult’s law, and depends on the existing mass of particles into which organic gases can dissolve. This raises the possibility of non-linear response of particle-phase OA to the emissions of precursor volatile organic compounds (VOCs) that contribute to this partitioning mass. Implications for air quality management are evident: A strong non-linear dependence would suggest that reductions in VOC emission would have a more-than-proportionate benefit in lowering ambient OA concentrations. Chamber measurements on simple VOC mixtures generally confirm the non-linear scaling between OA and VOCs, usually stated as amore » mass-dependence of the measured OA yields. However, for realistic ambient conditions including urban settings, no single component dominates the composition of the organic particles, and deviations from linearity are presumed to be small. Here we re-examine the linearity question using volatility spectra from several sources: (1) chamber studies of selected aerosols, (2) volatility inferred for aerosols sampled in two megacities, Mexico City and Paris, and (3) an explicit chemistry model (GECKO-A). These few available volatility distributions suggest that urban OA may be only slightly super-linear, with most values of the sensitivity exponent in the range 1.1-1.3, also substantially lower than seen in chambers for some specific aerosols. Furthermore, the rather low values suggest that OA concentrations in megacities are not an inevitable convergence of non-linear effects, but can be addressed (much like in smaller urban areas) by proportionate reductions in emissions.« less

  20. Epidemiology of untreated non-obstetric surgical disease in Burera District, Rwanda: a cross-sectional survey.

    PubMed

    Linden, Allison F; Maine, Rebecca; Hedt-Gauthier, Bethany L; Kamanzi, Emmanual; Mody, Gita; Ntakiyiruta, Georges; Kansayisa, Grace; Ntaganda, Edmond; Niyonkuru, Francine; Mubiligi, Joel; Mpunga, Tharcisse; Meara, John G; Riviello, Robert

    2015-04-27

    In low-income and middle-income countries, surgical epidemiology is largely undefined at the population level, with operative logs and hospital records serving as a proxy. This study assesses the distribution of surgical conditions that contribute the largest burden of surgical disease in Burera District, in northern Rwanda. We hypothesise that our results would yield higher rates of surgical disease than current estimates (from 2006) for similar low-income countries, which are 295 per 100 000 people. In March and May, 2012, we performed a cross-sectional study in Burera District, randomly sampling 30 villages with probability proportionate to size and randomly sampling 23 households within the selected villages. Six Rwandan surgical postgraduates and physicians conducted physical examinations on all eligible participants in sampled households. Participants were assessed for injuries or wounds, hernias, hydroceles, breast mass, neck mass, obstetric fistula, undescended testes, hypospadias, hydrocephalus, cleft lip or palate, and club foot. Ethical approval was obtained from Boston Children's Hospital (Boston, MA, USA) and the Rwandan National Ethics Committee (Kigali, Rwanda). Informed consent was obtained from all participants. Of the 2165 examined individuals, the overall prevalence of any surgical condition was 12% (95% CI 9·2-14·9) or 12 009 per 100 000 people. Injuries or wounds accounted for 55% of the prevalence and hernias or hydroceles accounted for 40%, followed by neck mass (4·2%), undescended testes (1·9%), breast mass (1·2%), club foot (1%), hypospadias (0·6%), hydrocephalus (0·6%), cleft lip or palate (0%), and obstetric fistula (0%). When comparing study participant characteristics, no statistical difference in overall prevalence was noted when examining sex, wealth, education, and travel time to the nearest hospital. Total rates of surgically treatable disease yielded a statistically significant difference compared with current estimates (p<0·001). Rates of surgically treatable disease are significantly higher than previous estimates in comparable low-income countries. The prevalence of surgically treatable disease is evenly distributed across demographic parameters. From these results, we conclude that strengthening the Rwandan health system's surgical capacity, particularly in rural areas, could have meaningful affect on the entire population. Further community-based surgical epidemiological studies are needed in low-income and middle-income countries to provide the best data available for health system planning. The Harvard Sheldon Traveling Fellowship. Copyright © 2015 Elsevier Ltd. All rights reserved.

  1. 14 CFR 1204.401 - Policy.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... educational institutions the opportunity to participate equitably and proportionately in its total purchases... the specific branch of science or technology required for the successful conduct of the work. It is in...

  2. Pregnancy in a woman with proportionate (primordial) dwarfism: a case report and literature review.

    PubMed

    Vance, C E; Desmond, M; Robinson, A; Johns, J; Zacharin, M; Savarirayan, R; König, K; Warrillow, S; Walker, S P

    2012-09-01

    Primordial dwarfism is a rare form of severe proportionate dwarfism which poses significant challenges in pregnancy. A 27-year-old with primordial dwarfism (height 97 cm, weight 22 kg) and coexisting morbidities of familial hypercholesterolaemia and hypertension presented to our unit. Early pregnancy was complicated by difficult blood pressure control, sinus tachycardia, biochemical hyperthyroidism and insulin-requiring gestational diabetes. Delivery was indicated at 24 weeks with uncontrollable hypertension, progressive renal impairment and intrauterine growth restriction. A caesarean section was performed under general anaesthesia, resulting in the delivery of a 486 g male infant. This case highlights the difficulties of managing pregnancy in a woman with primordial dwarfism. Her limited capacity to respond to the physiological demands of pregnancy created a life-threatening situation, culminating in profound preterm birth.

  3. Anaesthesia for dwarfs and other patients of pathological small stature.

    PubMed

    Walts, L F; Finerman, G; Wyatt, G M

    1975-11-01

    Sixty-nine anaesthetics were administered to 29 patients of pathological proportionate and disproportionate small stature. The anaesthetic course in most cases was uncomplicated. The few complications noted were similar in type and severity to those found in normal size patients undergoing similar anaesthesia and operative procedures. Achondroplastic dwarfs often develop neurological problems due to their bony deformities. General anaesthesia should be given preferential consideration in these patients. Non-achondroplastic dwarfs may have an associated odontoid dysplasia and if the neck is placed in flexion there is a potential risk of spinal cord damage. Tube size for proportionately small children is best estimated from body weight. No definite recommendations concerning proper tybe size in dwarfs can be given on the basis of the findings in the study.

  4. Learning Organization Profile of Educational Hospitals in Iran: Practice of Organizational Interlocking Systems.

    PubMed

    Mohebbifar, Rafat; Hashemi, Hassan Jahani; Rajaee, Roya; Najafi, Marziye; Etedal, Mahbobeh G H

    2015-02-24

    Organizational learning has been identified as necessary for different organizations to improve their performance in the changing and competitive environment. The main purpose of this research was to specify the learning organization profile of educational and health centers of Tehran and Qazvin Universities of Medical Sciences in Iran. The present research was conducted using a cross-sectional method in the academic year of 2013-2014. A staff of 530 from educational hospitals subordinated to Tehran and Qazvin universities of medical sciences participated in the research. The participants were selected using stratified random sampling. That is to say, a random sample of a proportionate size was selected from each hospital. The instrument for data collection was a Likert-scale questionnaire involving 50 items. The statistical techniques of ANOVA, t-test, Chi-square, correlation coefficients (Pearson and Spearman), and regression were utilized to analyze the data. All of them were performed using the Statistical Package for Social Sciences (SPSS) 16.0 for windows. the results indicated that 449 of participants (84.7%) had a B.S. degree and 78 of them (14.7%) had an M.S. or a Ph.D. degree. Among the fivefold dimensions of "Learning Organization" model (Learning, Organization, People, Knowledge, and Technology) in comparison of the two universities, the "people" dimension was the highest-rated dimension with the mean rating of 25.71±8.36 and the "learning" dimension was the lowest-rated dimension with the mean of 25.35±8.04. Comparison between the two universities yielded the result that educational hospitals in Tehran University of medical sciences with the rating of 126.56 had a more complete profile than that of educational hospitals in Qazvin university of medical sciences with the rating of 122.23. The hospitals of the two above-mentioned universities were, to a great extent, far from the characteristics of Learning Organization. In light of the massive mission of these centers to maintain and improve the community health and to train the skilled labor force, the centers should embark on updating the data and institutionalizing learning. Furthermore, to modify staff's behavior and performance and to achieve their goals, they should accentuate the importance of acquiring, creating, and transferring knowledge.

  5. Learning Organization Profile of Educational Hospitals in Iran: Practice of Organizational Interlocking Systems

    PubMed Central

    Mohebbifar, Rafat; Hashemi, Hassan Jahani; Rajaee, Roya; Najafi, Marziye; Etedal, Mahbobeh GH

    2015-01-01

    Background: Organizational learning has been identified as necessary for different organizations to improve their performance in the changing and competitive environment. Purpose: The main purpose of this research was to specify the learning organization profile of educational and health centers of Tehran and Qazvin Universities of Medical Sciences in Iran. Methodology: The present research was conducted using a cross-sectional method in the academic year of 2013-2014. A staff of 530 from educational hospitals subordinated to Tehran and Qazvin universities of medical sciences participated in the research. The participants were selected using stratified random sampling. That is to say, a random sample of a proportionate size was selected from each hospital. The instrument for data collection was a Likert-scale questionnaire involving 50 items. The statistical techniques of ANOVA, t-test, Chi-square, correlation coefficients (Pearson and Spearman), and regression were utilized to analyze the data. All of them were performed using the Statistical Package for Social Sciences (SPSS) 16.0 for windows. Result: The results indicated that 449 of participants (84.7%) had a B.S. degree and 78 of them (14.7%) had an M.S. or a Ph.D. degree. Among the fivefold dimensions of “Learning Organization” model (Learning, Organization, People, Knowledge, and Technology) in comparison of the two universities, the “people” dimension was the highest-rated dimension with the mean rating of 25.71±8.36 and the “learning” dimension was the lowest-rated dimension with the mean of 25.35±8.04. Comparison between the two universities yielded the result that educational hospitals in Tehran University of medical sciences with the rating of 126.56 had a more complete profile than that of educational hospitals in Qazvin university of medical sciences with the rating of 122.23. Conclusion: The hospitals of the two above-mentioned universities were, to a great extent, far from the characteristics of Learning Organization. In light of the massive mission of these centers to maintain and improve the community health and to train the skilled labor force, the centers should embark on updating the data and institutionalizing learning. Furthermore, to modify staff’s behavior and performance and to achieve their goals, they should accentuate the importance of acquiring, creating, and transferring knowledge. PMID:26156903

  6. A stitch in time: a cross-sectional survey looking at long lasting insecticide-treated bed net ownership, utilization and attrition in SNNPR, Ethiopia.

    PubMed

    Batisso, Esey; Habte, Tedila; Tesfaye, Gezahegn; Getachew, Dawit; Tekalegne, Agonafer; Kilian, Albert; Mpeka, Betty; Lynch, Caroline

    2012-06-07

    Since 2002/03, an estimated 4.7 million nets have been distributed in the Southern Nations, Nationalities and Peoples Region (SNNPR) among an at risk population of approximately 10 million people. Evidence from the region suggests that large-scale net ownership rapidly increased over a relatively short period of time. However, little is known about how coverage is being maintained given that the last mass distribution was in 2006/2007. This study sought to determine the status of current net ownership, utilization and rate of long lasting insecticide-treated nets (LLIN) loss in the previous three years in the context of planning for future net distribution to try to achieve sustainable universal coverage. A total of 750 household respondents were interviewed across malarious, rural kebeles of SNNPR. Households were randomly selected following a two-stage cluster sampling design where kebeles were defined as clusters. Kebeles were chosen using proportional population sampling (PPS), and 25 households within 30 kebeles randomly chosen. Approximately 67.5% (95%CI: 64.1-70.8) of households currently owned at least one net. An estimated 31.0% (95%CI 27.9-34.4) of all nets owned in the previous three years had been discarded by owners, the majority of whom considered the nets too torn, old or dirty (79.9%: 95%CI 75.8-84.0). Households reported that one-third of nets (33.7%) were less than one year old when they were discarded. The majority (58.8%) of currently owned nets had 'good' structural integrity according to a proportionate Hole Index. Nearly two-thirds of households (60.6%) reported using their nets the previous night. The overriding reason for not using nets was that they were too torn (45.7%, 95% CI 39.1-50.7). Yet, few households are making repairs to their nets (3.7%, 95% CI: 2.4-5.1). Results suggest that the life span of nets may be shorter than previously thought, with little maintenance by their owners. With the global move towards malaria elimination it makes sense to aim for sustained high coverage of LLINs. However, in the current economic climate, it also makes sense to hark back to simple tools and messages on the importance of careful net maintenance, which could increase their lifespans.

  7. Frailty effects in networks: comparison and identification of individual heterogeneity versus preferential attachment in evolving networks

    PubMed Central

    de Blasio, Birgitte Freiesleben; Seierstad, Taral Guldahl; Aalen, Odd O

    2011-01-01

    Preferential attachment is a proportionate growth process in networks, where nodes receive new links in proportion to their current degree. Preferential attachment is a popular generative mechanism to explain the widespread observation of power-law-distributed networks. An alternative explanation for the phenomenon is a randomly grown network with large individual variation in growth rates among the nodes (frailty). We derive analytically the distribution of individual rates, which will reproduce the connectivity distribution that is obtained from a general preferential attachment process (Yule process), and the structural differences between the two types of graphs are examined by simulations. We present a statistical test to distinguish the two generative mechanisms from each other and we apply the test to both simulated data and two real data sets of scientific citation and sexual partner networks. The findings from the latter analyses argue for frailty effects as an important mechanism underlying the dynamics of complex networks. PMID:21572513

  8. 20 CFR 653.100 - Purpose and scope of subpart.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... seasonal farmworkers (MSFWs) on a basis which is qualitatively equivalent and quantitatively proportionate to services provided to non-MSFWs. It also contains requirements that State agencies establish a...

  9. 20 CFR 653.100 - Purpose and scope of subpart.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... seasonal farmworkers (MSFWs) on a basis which is qualitatively equivalent and quantitatively proportionate to services provided to non-MSFWs. It also contains requirements that State agencies establish a...

  10. 20 CFR 653.100 - Purpose and scope of subpart.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... seasonal farmworkers (MSFWs) on a basis which is qualitatively equivalent and quantitatively proportionate to services provided to non-MSFWs. It also contains requirements that State agencies establish a...

  11. Beneficiary level factors influencing Janani Suraksha Yojana utilization in urban slum population of trans-Yamuna area of Delhi.

    PubMed

    Vikram, K; Sharma, A K; Kannan, A T

    2013-09-01

    Janani Suraksha Yojana (JSY), a conditional cash transfer scheme introduced to improve the institutional delivery rates and thereby reduce the maternal and infant mortality was implemented in all States and Union Territories of India from 2007. The present study was carried out to identify the beneficiary level factors of utilization of JSY scheme in urban slums and resettlement colonies of trans-Yamuna area of Delhi. A cross-sectional community based survey was done of mothers of infants in the selected areas of the two districts by stratified random sampling on a population proportionate basis. Socio-demographic factors, antenatal services availed and distance of nearest health facility were studied. Outcome variable, a beneficiary, was a woman who had ever interacted with the ASHA of her area during the antenatal period of previous pregnancy and had child birth in an institution. Descriptive tables were drawn; univariate analysis followed by multiple logistic regression was applied for identifying the predictors for availing the benefits. Of the 469 mothers interviewed, 333 (71%) had institutional delivery, 128 (27.3%) had benefited from JSY scheme and 68 (14.5%) had received cash benefits of JSY. Belonging to Hindu religion and having had more than 6 antenatal check ups were the significant predictors of availing the benefits of JSY. There is a need to improve the awareness among urban slum population about the utilization of JSY scheme. Targeting difficult to access areas with special measures and encouraging more antenatal visits were essential, prerequisites to improve the impact of JSY.

  12. Trends in the use of illicit substances in Thailand: Results from national household surveys.

    PubMed

    Angkurawaranon, Chaisiri; Jiraporncharoen, Wichuda; Likhitsathian, Surinporn; Thaikla, Kanittha; Kanato, Manop; Perngparn, Usaneya; Assanangkornchai, Sawitri; Aramrattana, Apinun

    2018-02-27

    Thailand borders some of the world's largest methamphetamine and opioid producing countries and trafficking routes. Thailand's 'War on Drugs' campaign was launched in 2003. This study reports trends in illicit substance use in Thailand over the period 2001-2011. National Household surveys on illicit drug use were conducted in 2001, 2003, 2007, 2008 and 2011. A stratified multi-stage cluster random sampling technique was implemented for each survey. Provinces in four regions were systematically selected using a probability proportionate to the size of the targeted population. Participants were interviewed using structured questionnaires on their history of substance use. The prevalence of illicit drug use within the past drastically decreased from 4.5% in 2001 to 1.0% in 2003 (P < 0.05). Since 2003, the prevalence of illicit use within the past year varied between 1.0% and 1.3%. By 2011, it was estimated that 0.84% have used kratom (a substance derived from Mitragyna speciosa) within the past year. Around 0.20% and 0.19% reported using cannibis and yaba (metamphetamine tablet) within a year of the 2011 survey. Other types of illicit drugs were less commonly used in Thailand. There was a decrease in prevalence of illicit drug use within the past year between 2001 and 2003 in Thailand. Since 2003, the past year prelavence of illicit drug use has remained relatively stable. From 2001 to 2011, cannabis, kratom and yaba have remained the three most commonly reported types of illicit drugs used in Thailand. © 2018 Australasian Professional Society on Alcohol and other Drugs.

  13. Primary care appointment availability and nonphysician providers one year after Medicaid expansion.

    PubMed

    Tipirneni, Renuka; Rhodes, Karin V; Hayward, Rodney A; Lichtenstein, Richard L; Choi, HwaJung; Reamer, Elyse N; Davis, Matthew M

    2016-06-01

    With insurance enrollment greater than expected under the Affordable Care Act, uncertainty about the availability and timeliness of healthcare services for newly insured individuals has increased. We examined primary care appointment availability and wait times for new Medicaid and privately insured patients before and after Medicaid expansion in Michigan. Simulated patient ("secret shopper") study. Extended follow-up of a previously reported simulated patient ("secret shopper") study assessing accessibility of routine new patient appointments in a stratified proportionate random sample of Michigan primary care practices before versus 4, 8, and 12 months after Medicaid expansion. During the study period, approximately 600,000 adults enrolled in Michigan's Medicaid expansion program, representing 57% of the previously uninsured nonelderly adult population. One year after expansion, we found that appointment availability remained increased by 6 percentage points for new Medicaid patients (95% CI, 1.6-11.1) and decreased by 2 percentage points for new privately insured patients (95% CI, -0.5 to -3.8). Over the same period, the proportion of appointments scheduled with nonphysician providers (nurse practitioners or physician assistants) increased from 8% to 21% of Medicaid appointments (95% CI, 5.6-20.2) and from 11% to 19% of private-insurance appointments (95% CI, 1.3-14.1). Median wait times remained stable for new Medicaid patients and increased slightly for new privately insured patients, both remaining within 2 weeks. During the first year following Medicaid expansion in Michigan, appointment availability for new Medicaid patients increased, a greater proportion of appointments could be obtained with nonphysician providers, and wait times remained within 2 weeks.

  14. Adherence to Healthcare Waste Management Guidelines among Nurses and Waste Handlers in Thika Sub-county- Kenya.

    PubMed

    Njue, P Mwaniki; Cheboi, K Solomon; Shadrak, Oiye

    2015-10-01

    Despite the set guidelines on Healthcare Waste Management in Kenya, mixing of different categories of waste, crude dumping and poor incineration are still a common phenomenon in public health facilities in Thika Subcounty, Kenya. Thika Subcounty generates 560 Kilograms of healthcare waste daily, which is risk to the many patients (admission rate of 26%). This may pose a potential environmental risk and be a source of disease diffusion. This research explored the adherence to healthcare waste management waste guidelines in health care facilities among the nurses and waste handlers. This was a cross sectional survey in which mixed methods were applied. A census and proportionate random sampling method were used. Quantitative data was analyzed using Statistical Package for Social Science (SPSS) version 20.0, while qualitative data was analyzed manually into themes. Full adherence to the seven waste disposal guidelines was low (16.3%). Knowledge on waste segregation, waste separation then disposal and means of transports were statistically significant in relation to adherence. The type of incinerator and burning status, protection maintenance and supply of adequate waste bins were also important to adherence level. Adherence level was low (16.3%,) and insignificantly different among nurses and waste handlers. From this finding, compliance remains a key challenge. Strategies targeted at contextualizing waste regulations and guidelines into local settings are necessary and important. Policy makers may design and implement standard incinerators across all the health facilities. This study is not exhaustive; therefore, it is necessary to carry out a study linking poor treatment and disposal of clinical waste to purported health outcomes in Kenya.

  15. 29 CFR 452.127 - Proportionate representation.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... matter for the union to determine in accordance with its constitution and bylaws. There is no indication... accordance with the labor organization's constitution and bylaws insofar as they are not inconsistent with...

  16. 29 CFR 452.127 - Proportionate representation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... matter for the union to determine in accordance with its constitution and bylaws. There is no indication... accordance with the labor organization's constitution and bylaws insofar as they are not inconsistent with...

  17. 29 CFR 452.127 - Proportionate representation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... matter for the union to determine in accordance with its constitution and bylaws. There is no indication... accordance with the labor organization's constitution and bylaws insofar as they are not inconsistent with...

  18. 29 CFR 452.127 - Proportionate representation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... matter for the union to determine in accordance with its constitution and bylaws. There is no indication... accordance with the labor organization's constitution and bylaws insofar as they are not inconsistent with...

  19. Rapid case-based mapping of seasonal malaria transmission risk for strategic elimination planning in Swaziland

    PubMed Central

    2013-01-01

    Background As successful malaria control programmes move towards elimination, they must identify residual transmission foci, target vector control to high-risk areas, focus on both asymptomatic and symptomatic infections, and manage importation risk. High spatial and temporal resolution maps of malaria risk can support all of these activities, but commonly available malaria maps are based on parasite rate, a poor metric for measuring malaria at extremely low prevalence. New approaches are required to provide case-based risk maps to countries seeking to identify remaining hotspots of transmission while managing the risk of transmission from imported cases. Methods Household locations and travel histories of confirmed malaria patients during 2011 were recorded through routine surveillance by the Swaziland National Malaria Control Programme for the higher transmission months of January to April and the lower transmission months of May to December. Household locations for patients with no travel history to endemic areas were compared against a random set of background points sampled proportionate to population density with respect to a set of variables related to environment, population density, vector control, and distance to the locations of identified imported cases. Comparisons were made separately for the high and low transmission seasons. The Random Forests regression tree classification approach was used to generate maps predicting the probability of a locally acquired case at 100 m resolution across Swaziland for each season. Results Results indicated that case households during the high transmission season tended to be located in areas of lower elevation, closer to bodies of water, in more sparsely populated areas, with lower rainfall and warmer temperatures, and closer to imported cases than random background points (all p < 0.001). Similar differences were evident during the low transmission season. Maps from the fit models suggested better predictive ability during the high season. Both models proved useful at predicting the locations of local cases identified in 2012. Conclusions The high-resolution mapping approaches described here can help elimination programmes understand the epidemiology of a disappearing disease. Generating case-based risk maps at high spatial and temporal resolution will allow control programmes to direct interventions proactively according to evidence-based measures of risk and ensure that the impact of limited resources is maximized to achieve and maintain malaria elimination. PMID:23398628

  20. Rapid case-based mapping of seasonal malaria transmission risk for strategic elimination planning in Swaziland.

    PubMed

    Cohen, Justin M; Dlamini, Sabelo; Novotny, Joseph M; Kandula, Deepika; Kunene, Simon; Tatem, Andrew J

    2013-02-11

    As successful malaria control programmes move towards elimination, they must identify residual transmission foci, target vector control to high-risk areas, focus on both asymptomatic and symptomatic infections, and manage importation risk. High spatial and temporal resolution maps of malaria risk can support all of these activities, but commonly available malaria maps are based on parasite rate, a poor metric for measuring malaria at extremely low prevalence. New approaches are required to provide case-based risk maps to countries seeking to identify remaining hotspots of transmission while managing the risk of transmission from imported cases. Household locations and travel histories of confirmed malaria patients during 2011 were recorded through routine surveillance by the Swaziland National Malaria Control Programme for the higher transmission months of January to April and the lower transmission months of May to December. Household locations for patients with no travel history to endemic areas were compared against a random set of background points sampled proportionate to population density with respect to a set of variables related to environment, population density, vector control, and distance to the locations of identified imported cases. Comparisons were made separately for the high and low transmission seasons. The Random Forests regression tree classification approach was used to generate maps predicting the probability of a locally acquired case at 100 m resolution across Swaziland for each season. Results indicated that case households during the high transmission season tended to be located in areas of lower elevation, closer to bodies of water, in more sparsely populated areas, with lower rainfall and warmer temperatures, and closer to imported cases than random background points (all p < 0.001). Similar differences were evident during the low transmission season. Maps from the fit models suggested better predictive ability during the high season. Both models proved useful at predicting the locations of local cases identified in 2012. The high-resolution mapping approaches described here can help elimination programmes understand the epidemiology of a disappearing disease. Generating case-based risk maps at high spatial and temporal resolution will allow control programmes to direct interventions proactively according to evidence-based measures of risk and ensure that the impact of limited resources is maximized to achieve and maintain malaria elimination.

  1. The Hallermann-Streiff Syndrome

    ERIC Educational Resources Information Center

    Judge, C.; Chakanovskis, Johanna E.

    1971-01-01

    A mentally handicapped 12 year old boy with the features of Hallermann-Streiff syndrome (proportionate dwarfism, beaked nose, small mouth, dental abnormalities, severe visual handicap) is described. A review of the literature is also included. (CD)

  2. Pregnancy in a woman with proportionate (primordial) dwarfism: a case report and literature review

    PubMed Central

    Vance, C E; Desmond, M; Robinson, A; Johns, J; Zacharin, M; Savarirayan, R; König, K; Warrillow, S; Walker, S P

    2012-01-01

    Primordial dwarfism is a rare form of severe proportionate dwarfism which poses significant challenges in pregnancy. A 27-year-old with primordial dwarfism (height 97 cm, weight 22 kg) and coexisting morbidities of familial hypercholesterolaemia and hypertension presented to our unit. Early pregnancy was complicated by difficult blood pressure control, sinus tachycardia, biochemical hyperthyroidism and insulin-requiring gestational diabetes. Delivery was indicated at 24 weeks with uncontrollable hypertension, progressive renal impairment and intrauterine growth restriction. A caesarean section was performed under general anaesthesia, resulting in the delivery of a 486 g male infant. This case highlights the difficulties of managing pregnancy in a woman with primordial dwarfism. Her limited capacity to respond to the physiological demands of pregnancy created a life-threatening situation, culminating in profound preterm birth. PMID:27582869

  3. Expatriates ill after travel: Results from the Geosentinel Surveillance Network

    PubMed Central

    2012-01-01

    Background Expatriates are a distinct population at unique risk for health problems related to their travel exposure. Methods We analyzed GeoSentinel data comparing ill returned expatriates with other travelers for demographics, travel characteristics, and proportionate morbidity (PM) for travel-related illness. Results Our study included 2,883 expatriates and 11,910 non-expatriates who visited GeoSentinel clinics ill after travel. Expatriates were more likely to be male, do volunteer work, be long-stay travelers (>6 months), and have sought pre-travel advice. Compared to non-expatriates, expatriates returning from Africa had higher proportionate morbidity (PM) for malaria, filariasis, schistosomiasis, and hepatitis E; expatriates from the Asia-Pacific region had higher PM for strongyloidiasis, depression, and anxiety; expatriates returning from Latin America had higher PM for mononucleosis and ingestion-related infections (giardiasis, brucellosis). Expatriates returning from all three regions had higher PM for latent TB, amebiasis, and gastrointestinal infections (other than acute diarrhea) compared to non-expatriates. When the data were stratified by travel reason, business expatriates had higher PM for febrile systemic illness (malaria and dengue) and vaccine-preventable infections (hepatitis A), and volunteer expatriates had higher PM for parasitic infections. Expatriates overall had higher adjusted odds ratios for latent TB and lower odds ratios for acute diarrhea and dermatologic illness. Conclusions Ill returned expatriates differ from other travelers in travel characteristics and proportionate morbidity for specific diseases, based on the region of exposure and travel reason. They are more likely to present with more serious illness. PMID:23273048

  4. Occurrence of the gasoline oxygenate MTBE and BTEX compounds in urban stormwater in the United States, 1991-95

    USGS Publications Warehouse

    Delzer, Gregory C.; Zogorski, John S.; Lopes, T.J.; Bosshart, R.L.

    1996-01-01

    Methyl tert-butyl ether (MTBE) is a gasoline oxygenate. Oxygenates such as MTBE, when added to gasoline, increase the gasoline's oxygen level and decrease vehicular carbon monoxide emissions and ozone levels in the atmosphere. MTBE disperses rapidly in water, was the second most frequently detected volatile organic compound (VOC) in a study of shallow urban ground water, and is less biodegradable than common gasoline compounds, such as benzene, toluene, ethylbenzene, and total xylene (BTEX). Urban stormwater is a possible source of MTBE found in shallow ground water. The U.S. Geological Survey (USGS) sampled stormwater in 16 cities and metropolitan areas that are required to obtain permits to discharge stormwater from their municipal storm-sewer system into surface water. Concentrations of 62 VOCs, including MTBE and BTEX compounds, were measured in 592 stormwater samples collected in these cities and metropolitan areas from 1991 through 1995. Concentration data for MTBE and BTEX compounds in stormwater were compiled and analyzed, and the findings are summarized in this report. This effort was part of an interagency assessment of the scientific basis and effectiveness of the Nation's oxygenated fuel program and was coordinated by the Office of Science and Technology Policy, Executive Office of the President. MTBE was the seventh most frequently detected VOC in urban stormwater, following toluene, total xylene, chloroform, total trimethylbenzene, tetrachloroethene, and naphthalene. MTBE was detected in 6.9 percentmg (41 of 592) of stormwater samples collected. When detected, concentrations of MTBE ranged from 0.2 to 8.7 micrograms per liter (ug/L), with a median of 1.5 ug/L. All detections of MTBE were less than the lower limit of the U.S. Environmental Protection Agency (EPA) draft lifetime health advisory (20 ug/L) for drinking water. Eighty- three percent of all detections of MTBE in stormwater were in samples collected during the October through March season of each year (1991- 95), which corresponds with the expected seasonal use of oxygenated gasoline in areas where carbon monoxide exceeds established air-quality standards. The median concentration of MTBE and benzene for all samples was statistically different and higher in samples collected during the October through March season than samples collected during the April through September season. Sixty-six percent of all MTBE detections occurred with BTEX compounds, and a proportionate increase in concentrations was found when these compounds occurred together. The proportionate increase could indicate a common source of MTBE and BTEX for those samples. Toluene and total xylene were the most frequently detected BTEX compounds and the most frequently detected VOCs in these investigations. Detected concentrations of toluene and total xylene ranged from 0.2 to 6.6 ug/L and 0.2 to 15 ug/L with median concentrations of 0.3 and 0.4 ug/L, respectively.

  5. Consumption of junk foods by school-aged children in rural Himachal Pradesh, India.

    PubMed

    Gupta, Aakriti; Kapil, Umesh; Singh, Gajendra

    2018-01-01

    There has been an increase in the consumption of junk food (JF) among school-aged children (SAC) possibly leading to obesity and diet-related diseases among them. We do not have evidence on consumption of JF in rural areas; hence, we conducted a study to assess the consumption of JF by SAC in rural, Himachal Pradesh. A total of 425 children in the age group of 12-18 years studying in 30 government schools (clusters) were included. The clusters were selected using population proportionate to size sampling methodology. We found high prevalence (36%) of consumption of JF among SAC during the last 24 h. Efforts should be taken to reduce the consumption of JF by promotion of healthy dietary habits and educating children about the ill effects of JF.

  6. WHISPER or SHOUT study: protocol of a cluster-randomised controlled trial assessing mHealth sexual reproductive health and nutrition interventions among female sex workers in Mombasa, Kenya

    PubMed Central

    Ampt, Frances H; Mudogo, Collins; Gichangi, Peter; Lim, Megan S C; Manguro, Griffins; Chersich, Matthew; Jaoko, Walter; Temmerman, Marleen; Laini, Marilyn; Comrie-Thomson, Liz; Stoové, Mark; Agius, Paul A; Hellard, Margaret; L’Engle, Kelly; Luchters, Stanley

    2017-01-01

    Introduction New interventions are required to reduce unintended pregnancies among female sex workers (FSWs) in low- and middle-income countries and to improve their nutritional health. Given sex workers’ high mobile phone usage, repeated exposure to short messaging service (SMS) messages could address individual and interpersonal barriers to contraceptive uptake and better nutrition. Methods In this two-arm cluster randomised trial, each arm constitutes an equal-attention control group for the other. SMS messages were developed systematically, participatory and theory-driven and cover either sexual and reproductive health (WHISPER) or nutrition (SHOUT). Messages are sent to participants 2–3 times/week for 12 months and include fact-based and motivational content as well as role model stories. Participants can send reply texts to obtain additional information. Sex work venues (clusters) in Mombasa, Kenya, were randomly sampled with a probability proportionate to venue size. Up to 10 women were recruited from each venue to enrol 860 women. FSWs aged 16–35 years, who owned a mobile phone and were not pregnant at enrolment were eligible. Structured questionnaires, pregnancy tests, HIV and syphilis rapid tests and full blood counts were performed at enrolment, with subsequent visits at 6 and 12 months. Analysis The primary outcomes of WHISPER and SHOUT are unintended pregnancy incidence and prevalence of anaemia at 12 months, respectively. Each will be compared between study groups using discrete-time survival analysis. Potential limitations Contamination may occur if participants discuss their intervention with those in the other trial arm. This is mitigated by cluster recruitment and only sampling a small proportion of sex work venues from the sampling frame. Conclusions The design allows for the simultaneous testing of two independent mHealth interventions for which messaging frequency and study procedures are identical. This trial may guide future mHealth initiatives and provide methodological insights into use of reciprocal control groups. Trial registration number ACTRN12616000852459; Pre-results. PMID:28821530

  7. 13 CFR 115.67 - Changes in Contract or bond amount.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... as initial guaranteed bond issuances (see § 115.65(c)(1)). The Surety must present checks for... Principal a proportionate amount of the guarantee fee, and adjust SBA's Premium share accordingly in the...

  8. Modeling Olympus Mons from the Earth.

    ERIC Educational Resources Information Center

    Lebofsky, Nancy R.; Lebofsky, Larry A.

    2002-01-01

    Presents a science activity using cubes for constructing the "Olympus Mons" model, the largest known volcano in the solar system. Uses the Catalina Mountains as a real-life comparison and builds a scale-proportionate model. (YDS)

  9. Impact of Maternal Education about Complementary Feeding on Their Infants' Nutritional Outcomes in Low- and Middle-income Households: A Community-based Randomized Interventional Study in Karachi, Pakistan

    PubMed Central

    Saleem, Ali Faisal; Mahmud, Sadia; Baig-Ansari, Naila

    2014-01-01

    ABSTRACT This cluster-randomized interventional trial at peri-urban settings of Karachi was conducted to evaluate the impact of maternal educational messages regarding appropriate complementary feeding (CF) on the nutritional status of their infants after 30 weeks of educational interventions delivered by trained community health workers. Mothers in the intervention group received three education modules about breastfeeding (BF) and appropriate CF at a baseline visit and two subsequent visits 10 weeks apart. The control group received advice about BF according to national guidelines. Infants' growth [weight, length, and mid-upper arm-circumference (MUAC), stunting, wasting, and underweight] were measured at four time points. At the end of the study, infants in the intervention group had a higher mean weight of 350 g (p=0.001); length of 0.66 cm (p=0.001), and MUAC of 0.46 cm (p=0.002) compared to the controls; proportionate reduction of stunting and underweight were 10% (84% vs 74%; ORadj 8.36 (5.6-12.42) and 5% (25% vs 20%; ORadj 0.75 (0.4-1.79) in the intervention compared to the control group. For relatively food-secure populations, educational interventions about appropriate CF to mothers had a direct positive impact on linear growth of their infants. PMID:25895196

  10. 21 CFR 610.13 - Purity.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... substances is not required for the following products: Products containing formed blood elements... antigens; toxoids; toxins; allergenic extracts; venoms; diagnostic substances and trivalent organic... human blood; (ii) for Streptokinase, the test dose shall be at least equivalent proportionately, on a...

  11. 21 CFR 610.13 - Purity.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... substances is not required for the following products: Products containing formed blood elements... antigens; toxoids; toxins; allergenic extracts; venoms; diagnostic substances and trivalent organic... human blood; (ii) for Streptokinase, the test dose shall be at least equivalent proportionately, on a...

  12. 21 CFR 610.13 - Purity.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... substances is not required for the following products: Products containing formed blood elements... antigens; toxoids; toxins; allergenic extracts; venoms; diagnostic substances and trivalent organic... human blood; (ii) for Streptokinase, the test dose shall be at least equivalent proportionately, on a...

  13. 21 CFR 610.13 - Purity.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... substances is not required for the following products: Products containing formed blood elements... antigens; toxoids; toxins; allergenic extracts; venoms; diagnostic substances and trivalent organic... human blood; (ii) for Streptokinase, the test dose shall be at least equivalent proportionately, on a...

  14. 21 CFR 610.13 - Purity.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... substances is not required for the following products: Products containing formed blood elements... antigens; toxoids; toxins; allergenic extracts; venoms; diagnostic substances and trivalent organic... human blood; (ii) for Streptokinase, the test dose shall be at least equivalent proportionately, on a...

  15. A low complexity reweighted proportionate affine projection algorithm with memory and row action projection

    NASA Astrophysics Data System (ADS)

    Liu, Jianming; Grant, Steven L.; Benesty, Jacob

    2015-12-01

    A new reweighted proportionate affine projection algorithm (RPAPA) with memory and row action projection (MRAP) is proposed in this paper. The reweighted PAPA is derived from a family of sparseness measures, which demonstrate performance similar to mu-law and the l 0 norm PAPA but with lower computational complexity. The sparseness of the channel is taken into account to improve the performance for dispersive system identification. Meanwhile, the memory of the filter's coefficients is combined with row action projections (RAP) to significantly reduce computational complexity. Simulation results demonstrate that the proposed RPAPA MRAP algorithm outperforms both the affine projection algorithm (APA) and PAPA, and has performance similar to l 0 PAPA and mu-law PAPA, in terms of convergence speed and tracking ability. Meanwhile, the proposed RPAPA MRAP has much lower computational complexity than PAPA, mu-law PAPA, and l 0 PAPA, etc., which makes it very appealing for real-time implementation.

  16. Common themes in changing vector-borne disease scenarios.

    PubMed

    Molyneux, David H

    2003-01-01

    The impact of climate change on disease patterns is controversial. However, global burden of disease studies suggest that infectious diseases will contribute a proportionately smaller burden of disease over the next 2 decades as non-communicable diseases emerge as public health problems. However, infectious diseases contribute proportionately more in the poorest quintile of the population. Notwithstanding the different views of the impact of global warming on vector-borne infections this paper reviews the conditions which drive the changing epidemiology of these infections and suggests that such change is linked by common themes including interactions of generalist vectors and reservoir hosts at interfaces with humans, reduced biodiversity associated with anthropogenic environmental changes, increases in Plasmodium falciparum: P. vivax ratios and well-described land use changes such as hydrological, urbanization, agricultural, mining and forest-associated impacts (extractive activities, road building, deforestation and migration) which are seen on a global scale.

  17. Causes of death among persons with multiple sclerosis.

    PubMed

    Cutter, Gary R; Zimmerman, Jeffrey; Salter, Amber R; Knappertz, Volker; Suarez, Gustavo; Waterbor, John; Howard, Virginia J; Ann Marrie, Ruth

    2015-09-01

    Multiple Sclerosis (MS) is a leading cause of disability among young Americans. Reports suggest that life expectancy (i.e., average age at death) remains reduced as compared to the general population, but underlying causes of death (UCOD) are less well-characterized. To describe the cause-specific mortality among participants enrolled in the North American Research Committee on Multiple Sclerosis (NARCOMS) registry and to compare the profile of these causes by age, sex, race and disability status at entry into NARCOMS, with U.S. mortality data. The underlying cause of death (UCOD), any mention cause of death and proportionate mortality were compared among U.S. NARCOMS participants by age, sex, race and disability status. Of the 32,445 participants to be considered for this study, 2,927 had died. Compared to survivors, decedents were older at enrollment and MS diagnosis, more likely to be male, and had less education. UCOD differed markedly by age group. In both sexes, MS as the UCOD was proportionately lower by 20% or more in those aged 25-39 compared to those aged 75 or older. Cancer and cardiovascular causes were more frequent as causes of death with increasing age, but were less than expected at older ages. The effect of disability on mortality was roughly equivalent to the effect of aging on mortality. Among NARCOMS participants older age at enrollment, male sex and greater disability were associated with increased mortality risk. This cohort of MS subjects had a lower proportionate mortality from cardiovascular disease and cancer compared to the U.S. population. Copyright © 2015 Elsevier B.V. All rights reserved.

  18. 26 CFR 301.6222(a)-1 - Consistent treatment of partnership items.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    .... Partnership P incurred certain start-up costs before P was actively engaged in its business. P capitalized these costs. C, a partner in P, deducted C's proportionate share of these start-up costs. C's treatment...

  19. 18 CFR 301.2 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... OF ENERGY REGULATIONS FOR FEDERAL POWER MARKETING ADMINISTRATIONS AVERAGE SYSTEM COST METHODOLOGY FOR... the adjusted historical load for each customer proportionately scaled to Tier 1 System Resources and adjusted for conservation achieved. The CHWM is specified in each eligible customer's CHWM Contract...

  20. A Potential Threat to School-Finance Reform

    ERIC Educational Resources Information Center

    Odden, Allan

    1975-01-01

    The revisionist view that property taxes are progressive rather than regressive is contradicted by research that shows the property tax takes proportionately more from the low-income taxpayer than it does from the middle- or high-income taxpayer. (Author/MLF)

  1. Screening for acute childhood malnutrition during the National Nutrition Week in mali increases treatment referrals.

    PubMed

    Nyirandutiye, Daniele H; Ag Iknane, Akory; Fofana, Amadou; Brown, Kenneth H

    2011-01-01

    To evaluate a pilot intervention designed to integrate mid-upper arm circumference (MUAC) screening for acute malnutrition into the semi-annual Child Nutrition Week (Semaine d'Intensification des Activités de Nutrition, or "SIAN") activities carried out in June 2008. A cross-sectional survey was conducted in Kolokani and Nara, two health districts in the Koulikoro region of Mali, 4-5 months after the SIAN, using a population-proportionate, multi-stage random sample of: 1) health centers, and 2) households in communities linked to each of the selected health centers. Caregivers of 1543 children who were 6-59 months of age at the time of the SIAN, 17 community-based volunteers and 45 health center staff members were interviewed. A total of 1278 children 6-59 months (83% of those studied) reportedly participated in SIAN. Of the participating children, 1258 received vitamin A (98% of SIAN participants; 82% of all eligible children), 945 received anti-helminth tablets (84% of participants; 71% of eligibles), and 669 were screened for acute malnutrition (52% of participants; 43% of eligibles). 186 of the children screened (27%) were reportedly identified as acutely malnourished. SIAN screening covered a significantly greater proportion of children than were examined in both community-based (22% of children) and health center-based screening activities (5% of children) combined during the 4-5 months after the SIAN (P<0.0001). In general, community volunteers and health personnel positively evaluated their experience adding MUAC screening to SIAN. Integrating MUAC screening for acute malnutrition in SIAN permits the assessment of a large number of children for acute malnutrition, and should be continued.

  2. Domestic violence and its impact on married women's health in Eastern Saudi Arabia.

    PubMed

    Afifi, Zeinab Emam M; Al-Muhaideb, Nouriah S; Hadish, Nina F; Ismail, Faten I; Al-Qeamy, Fatema M

    2011-06-01

    To identify the prevalence of domestic violence (DV) in Al-Ahsa, and its impact on married women's health. This study is a community-based cross-sectional survey conducted from January to June 2010 in Al-Ahsa oasis in the Eastern province of the Kingdom of Saudi Arabia. It included 2000 ever-married women, 15-60 years old, and selected by a 2-stage proportionate cluster random sample. Data was gathered through structured interviews. Univariate and multivariate analysis was carried out using the Statistical Package for Social Sciences version 15. The prevalence of lifetime DV was 39.3%, 35.9% for mental, 17.9% for physical, and 6.9% for sexual violence. Lower rates of recent (within one month prior to the interview) violence were encountered, that is: overall (32.7%); mental (29.1%); physical (22.8%); and sexual (11.8%). Eleven percent of women were beaten, and 7% were kicked on the abdomen during pregnancy. Lifetime violence was significantly associated with perceived bad general health, disease, abortion, hemorrhage, and body mass index. Recent violence increased the number of doctor visits, and the odds of feeling dizzy (OR=1.93), vaginal bleeding (OR=1.83), movement and activity problems, pain, taking drugs (OR=1.95), and stress significantly during the last 4 weeks before the interview. A large proportion of women tolerated violence without seeking help (41.4%). Common reactions included complaining to own family, treating the perpetrator violently, and complaining to a friend. We found that DV is prevalent in Al-Ahsa. We recommend awareness programs aiming at educating current and future couples, and proper training of health care providers in assisting the cases of DV.

  3. Screening for Acute Childhood Malnutrition during the National Nutrition Week in Mali Increases Treatment Referrals

    PubMed Central

    Nyirandutiye, Daniele H.; Ag Iknane, Akory; Fofana, Amadou; Brown, Kenneth H.

    2011-01-01

    Objective To evaluate a pilot intervention designed to integrate mid-upper arm circumference (MUAC) screening for acute malnutrition into the semi-annual Child Nutrition Week (Semaine d'Intensification des Activités de Nutrition, or “SIAN”) activities carried out in June 2008. Design A cross-sectional survey was conducted in Kolokani and Nara, two health districts in the Koulikoro region of Mali, 4–5 months after the SIAN, using a population-proportionate, multi-stage random sample of: 1) health centers, and 2) households in communities linked to each of the selected health centers. Caregivers of 1543 children who were 6–59 months of age at the time of the SIAN, 17 community-based volunteers and 45 health center staff members were interviewed. Results A total of 1278 children 6–59 months (83% of those studied) reportedly participated in SIAN. Of the participating children, 1258 received vitamin A (98% of SIAN participants; 82% of all eligible children), 945 received anti-helminth tablets (84% of participants; 71% of eligibles), and 669 were screened for acute malnutrition (52% of participants; 43% of eligibles). 186 of the children screened (27%) were reportedly identified as acutely malnourished. SIAN screening covered a significantly greater proportion of children than were examined in both community-based (22% of children) and health center-based screening activities (5% of children) combined during the 4-5 months after the SIAN (P<0.0001). In general, community volunteers and health personnel positively evaluated their experience adding MUAC screening to SIAN. Conclusion Integrating MUAC screening for acute malnutrition in SIAN permits the assessment of a large number of children for acute malnutrition, and should be continued. PMID:21731602

  4. [Consumption of sugar-sweetened beverages among 18 years old and over adults in 2010-2012 in China].

    PubMed

    Guo, Haijun; Zhao, Liyun; Xu, Xiaoli; Yu, Wentao; Ju, Lahong; Yu, Dongmei

    2018-01-01

    To investigate consumption of sugar-sweetened beverages among Chinese adults in 2010-2012. Data was collected from Chinese Nutrition and Health Surveillance: 2010-2012. Multi-stage stratified random cluster and probability proportionate sampling method was used, and 45 203 respondents aged 18 and over from 150 sites of 31 provinces, autonomous regions and municipalities were involved in the analysis. The consumption rate of sugar-sweetened beverages, distribution of the classification of the consumption frequency and percentage of variety beverages consumption frequency were calculated. There were 50. 1% of Chinese adults in2010-2012 consuming sugar-sweetened beverages, men and women were 49. 2% and 50. 8%, for age groups of 18-44, 45-59 and 60 and over, the consumption rates were65. 4% %, 47. 0% % 36. 3%, respectively. The prevalence in cities was 49. 0% and in counties was 51. 3%. The rate of consuming 1 time/week and over was 15. 3% and consuming 1 time/day was 1. 3%. As the economical level decreased, the two rates decreased. Carbonated beverages had the highest consumption frequency( 39. 8%), and the lactic acid beverages had the lowest( 10. 8%). Consumption of carbonated beverages in men( 44. 8%) was higher than that in women( 35. 3%), while for the fruit and vegetable juice, lactic acid beverages, disposable milk beverages and coffee, the consumption in women were higher than that in men. As the economical level decreased, consumption of carbonated and disposable milk beverages were increasing, and lactic acid beverages and coffee were decreasing significantly. The consumption of sugar-sweetened beverages among adults in 2010-2012 was relatively high. The targeted nutrition health education and intervention was needed and implemented to decrease the consumption of sugar-sweetened beverages.

  5. Prevalence of pollen-induced allergic rhinitis with high pollen exposure in grasslands of northern China.

    PubMed

    Wang, X-Y; Ma, T-T; Wang, X-Y; Zhuang, Y; Wang, X-D; Ning, H-Y; Shi, H-Y; Yu, R-L; Yan, D; Huang, H-D; Bai, Y-F; Shan, G-L; Zhang, B; Song, Q-K; Zhang, Y-F; Zhang, T-J; Jia, D-Z; Liu, X-L; Kang, Z-X; Yan, W-J; Yang, B-T; Bao, X-Z; Sun, S-H; Zhang, F-F; Yu, W-H; Bai, C-L; Wei, T; Yang, T; Ma, T-Q; Wu, X-B; Liu, J-G; Du, H; Zhang, L; Yan, Y; Wang, D-Y

    2018-06-01

    The aim of this study was to investigate the prevalence of epidemiologic and physician-diagnosed pollen-induced AR (PiAR) in the grasslands of northern China and to study the impact of the intensity and time of pollen exposure on PiAR prevalence. A multistage, clustered and proportionately stratified random sampling with a field interviewer-administered survey study was performed together with skin prick tests (SPT) and measurements of the daily pollen count. A total of 6043 subjects completed the study, with a proportion of 32.4% epidemiologic AR and 18.5% PiAR. The prevalence was higher in males than females (19.6% vs 17.4%, P = .024), but no difference between the two major residential and ethnic groups (Han and Mongolian) was observed. Subjects from urban areas showed higher prevalence of PiAR than rural areas (23.1% vs 14.0%, P < .001). Most PiAR patients were sensitized to two or more pollens (79.4%) with artemisia, chenopodium, and humulus scandens being the most common pollen types, which were similarly found as the top three sensitizing pollen allergens by SPT. There were significant regional differences in the prevalence of epidemiologic AR (from 18.6% to 52.9%) and PiAR (from 10.5% to 31.4%) among the six areas investigated. PiAR symptoms were positively associated with pollen counts, temperature, and precipitation (P < .05), but negatively with wind speed and pressure P < .05). Pollen-induced AR (PiAR) prevalence in the investigated region is extremely high due to high seasonal pollen exposure, which was influenced by local environmental and climate conditions. © 2018 The Authors. Allergy Published by John Wiley and Sons Ltd.

  6. Motivating factors among Iranian nurses

    PubMed Central

    Negarandeh, Reza; Dehghan-Nayeri, Nahid; Ghasemi, Elham

    2015-01-01

    Background: One of the most important challenges of Iranian health care system is “quality of care,” and it is assumed that motivated nurses are more ready to provide better care. There are limited studies investigating Iranian nurses’ motivations; however, factors which motivate them have not been studied yet. Identifying the motivating factors enables nurse managers to inspire nurses for continuous quality improvement. The aim of this study was to identify motivating factors for Iranian hospital nurses. Materials and Methods: This is a cross-sectional descriptive study in which 310 nurses working at 14 hospitals of Tehran University of Medical Sciences were selected by proportionate stratified random sampling. Data were collected in 2010 by a researcher-developed questionnaire. Descriptive statistics and independent t-test, analysis of variance, Tukey post-hoc test, Chi-Square and Fisher's exact test were used for statistical analysis by Statistical Package for Social Sciences (SPSS) version 16. Results: The mean score of motivation was 90.53 ± 10.76 (range: 59–121). Four motivating factors including “career development” (22.63 ± 5.66), “job characteristics” (34.29 ± 4), “job authority” (18.48 ± 2.79), and “recognition” (15.12 ± 2.5) were recognized. The least mean of the motivation score, considering the number of items, was 3.23 for career development, while the highest mean was 3.81 for job characteristics. Conclusions: The findings showed that motivation of nurses was at a medium level, which calls for improvement. The factors that have the greatest potential to motivate nurses were identified in this study and they can help managers to achieve the goal of continuous quality improvement. PMID:26257797

  7. Double trouble: Exploring the association between waterpipe tobacco smoking and the nonmedical use of psychoactive prescription drugs among adolescents.

    PubMed

    Zahlan, Leona; Ghandour, Lilian; Yassin, Nasser; Afifi, Rima; Martins, Silvia S

    2014-12-01

    In youth, both waterpipe tobacco smoking (WTS) and nonmedical use of prescription drugs (NMUPD) are globally growing concerns. This study assesses for the first time the lifetime and past-year associations between WTS and four classes of psychoactive prescription drugs. Cross-sectional data (2011) on 986 high school students attending public and private high schools in Beirut (Lebanon) was analyzed. Schools were selected using proportionate random cluster sampling from a comprehensive list of schools provided by the Ministry of Education. Almost half (46%) had tried WTS compared to 25% who had ever tried cigarettes. Lifetime prevalence estimates of NMUPD were: pain relievers (8.2%), sedatives/tranquilizers (5.6%), stimulants (3.5%), antidepressants (2.5%), and sleeping pills (2.3%). WTS was associated with increased odds of sedatives/tranquilizer use (OR = 3.22, 95% CI: 1.25, 8.25), pain reliever use (OR = 4.31, 95% CI: 2.02, 9.17), and sleeping medication use (OR = 8.31, 95% CI: 2.37, 29.20), controlling for sex, age, school type, and other substance use. For cigarettes, the associations were consistently either weaker or non-existent, except with stimulant use (OR = 5.29, 95% CI: 1.55, 18.05). While public health professionals have watched with caution the global prevalence of youth cigarette use-worldwide, an insidious alternative form of tobacco use has grown. Further research is needed to understand the unique risk factors and motives associated with WTS and how these relate to NMUPD in order to inform the development of effective intervention programs and policies that support youth positive health decisions. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  8. Epidemiological studies of tooth wear and dental erosion in 14-year old children in North West England. Part 2: The association of diet and habits.

    PubMed

    Milosevic, A; Bardsley, P F; Taylor, S

    2004-10-23

    To determine the strength of association (expressed as Odds Ratios) of potential risk factors with erosion and tooth wear in 14-year-old schoolchildren. A random sample of 2,385 children were selected by a stratified two-stage technique based on schools and children. Schools in NW England. Tooth wear was assessed by one examiner on three surfaces of all 12 anterior teeth (labial, incisal and palatal) and the occlusal surface of all four first molars using a four-point scale. Enamel wear was scored 0, dentine exposure <1/3 scored 1, >1/3 scored 2 and secondary dentine or pulpal exposure, scored 3. A questionnaire enquired about general health, dental health, habits and the frequency of intake of a wide range of foods and drinks. The Odds Ratios for tooth wear on any surface for habits, reflux and certain foods were: bruxism, 1.10; stomach upset, 1.45; pickles 1.86; vinegar 1.36; salt and vinegar crisps 1.33; brown/other sauces 1.57. Similarly, the odds ratios for potentially erosive drinks were: fizzy drinks 1.32; sport drinks 1.58; herbal/lemon tea 3.97. The frequency of intake was bi-modal with 397 children drinking a can per day and 207 drinking two cans per day. A significant number drank acidic beverages at bedtime but this was not associated with dental erosion. Although odds ratios greater than unity indicate an association, this was not high for carbonated beverages and many other acidic foods or drinks. Examining at fourteen years may not be ideal, as the determinants of erosion/tooth wear have not acted for long, the indices do not discriminate sufficiently and proportionately few subjects have dentine exposed on smooth surfaces.

  9. Gender, marital status, and commercially prepared food expenditure.

    PubMed

    Kroshus, Emily

    2008-01-01

    Assess how per capita expenditure on commercially prepared food as a proportion of total food expenditure varies by the sex and marital status of the head of the household. Prospective cohort study, data collected by the United States Bureau of Labor Statistics 2004 Consumer Expenditure Survey. United States. Randomly selected nationally representative sample of 5744 US citizens. Per capita spending on commercially prepared food (dependent variable) for every $1 increase in total per capita food spending (independent variable). Linear regressions run separately for each permutation of gender and marital status (never married, married, divorced/separated). Proportionate per capita household expenditure on commercially prepared food was found to vary by marital status and gender. Households headed by unmarried men (both divorced/separated and never married) spent a significantly greater proportion of their food budget on commercially prepared food than their married male peers (38% and 60% higher, respectively). Regardless of marital status, households headed by women were found to spend approximately one-third of their total food budget on commercially prepared foods outside the home. Households headed by never married men spent 63% more per capita than those headed by never married women and households headed by divorced or separated men spent 37% more than those headed by divorced or separated women. Marital status is significantly related to the dietary patterns of households headed by men. In light of the high rates of divorce, separation, and delay of marriage, marriage cannot be considered an inclusive or permanent solution to changing male eating patterns. It is important that nutrition educators learn more about the dietary patterns of households headed by males outside the institution of marriage.

  10. The impact of general health and social support on health promoting lifestyle in the first year postpartum: the structural equation modelling

    PubMed Central

    Hajimiri, Khadijeh; Shakibazadeh, Elham; Mehrizi, Ali Asghar Haeri; Shabbidar, Sakineh

    2018-01-01

    Background and aim Postpartum is a critical period for mothers which often leads to neglect of their own health. Mothers’ new responsibilities may affect their health promoting lifestyle (HPL). The aim of this study was to determine the impact of both general health and social support on health-promoting lifestyle. Methods A cross-sectional survey was conducted on 310 women who gave birth over a one-year period in Zanjan (Iran), 2016. A proportionate stratified random sampling technique was used to select respondents from each stratum. Health-promoting lifestyle was assessed using the health-promoting lifestyle profile II (HPLP II) scale. A structure equation model (SEM) was used to determine the relationship between observed and latent variables. Data were analysed using SPSS version 22 and LISREL 8.5 software. Results The age of 42.6% of the participants was more than 30 years and 40.3% of them had an academic education. The mean score of the health-promoting lifestyle was 131.28 (15.37). The structural equation model fitted well with RMSEA =0.07, CFI=0.92, and GFI=0.94. Among the latent factors, general health, with a factor load of −0.68, had greater impact on health-promoting lifestyle than social support. Moreover, there was a significant correlation (−0.63) between general health and perceived social support in the postpartum period. Conclusion health-promoting lifestyle was not at appropriate levels among women in the first year after delivery. These findings suggest that strengthening general health and social support would improve a health-promoting lifestyle in Iranian postpartum women. PMID:29588825

  11. 5 CFR 950.106 - PCFO expense recovery.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... VOLUNTARY ORGANIZATIONS General Provisions § 950.106 PCFO expense recovery. (a) The PCFO shall recover from... 950.106 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS... shared proportionately by all the recipient organizations reflecting their percentage share of gross...

  12. 5 CFR 950.106 - PCFO expense recovery.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... VOLUNTARY ORGANIZATIONS General Provisions § 950.106 PCFO expense recovery. (a) The PCFO shall recover from... 950.106 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS... shared proportionately by all the recipient organizations reflecting their percentage share of gross...

  13. 5 CFR 950.106 - PCFO expense recovery.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... VOLUNTARY ORGANIZATIONS General Provisions § 950.106 PCFO expense recovery. (a) The PCFO shall recover from... 950.106 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS... shared proportionately by all the recipient organizations reflecting their percentage share of gross...

  14. 5 CFR 950.106 - PCFO expense recovery.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... VOLUNTARY ORGANIZATIONS General Provisions § 950.106 PCFO expense recovery. (a) The PCFO shall recover from... 950.106 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS... shared proportionately by all the recipient organizations reflecting their percentage share of gross...

  15. 5 CFR 950.106 - PCFO expense recovery.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... VOLUNTARY ORGANIZATIONS General Provisions § 950.106 PCFO expense recovery. (a) The PCFO shall recover from... 950.106 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS... shared proportionately by all the recipient organizations reflecting their percentage share of gross...

  16. Parameters for good welding of copper to nickel

    NASA Technical Reports Server (NTRS)

    Hall, L. G.

    1969-01-01

    Quality in welding copper leads to nickel bus wires is obtained by the mass of nickel exceeding that of copper. Welding range 2ncreases proportionately with the increase in the nickel-to-copper mass ratio up to 4-to-1.

  17. Monitoring agricultural processing electrical energy use and efficiency

    USDA-ARS?s Scientific Manuscript database

    Energy costs have become proportionately larger as cotton post-harvest processing facilities have utilized other inputs more efficiently. A discrepancy in energy consumption per unit processed between facilities suggests that energy could be utilized more efficiently. Cotton gin facilities were in...

  18. 75 FR 13623 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-22

    ... ``immediate family'' shall include parents, mother-in-law or father-in-law, husband or wife, children or any... direct proportionate share limitation of paragraph (1)(A)(iii) are accounts of the immediate family of...

  19. Determinants of Exposure to Fragranced Product Chemical Mixtures in a Sample of Twins

    PubMed Central

    Gribble, Matthew O.; Bandeen-Roche, Karen; Fox, Mary A.

    2015-01-01

    Fragranced product chemical mixtures may be relevant for environmental health, but little is known about exposure. We analyzed results from an olfactory challenge with the synthetic musk fragrance 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethyl-cyclopento-γ-2-benzopyran (HHCB), and a questionnaire about attitudes toward chemical safety and use of fragranced products, in a sample of 140 white and 17 black twin pairs attending a festival in Ohio. Data for each product were analyzed using robust ordered logistic regressions with random intercepts for “twin pair” and “sharing address with twin”, and fixed effects for sex, age, education, and “ever being bothered by fragrances”. Due to the small number of black participants, models were restricted to white participants except when examining racial differences. Overall patterns of association were summarized across product-types through random-effects meta-analysis. Principal components analysis was used to summarize clustering of product use. The dominant axis of variability in fragranced product use was “more vs. less”, followed by a distinction between household cleaning products and personal care products. Overall, males used fragranced products less frequently than females (adjusted proportionate odds ratio 0.55, 95% confidence interval 0.33, 0.93). This disparity was driven by personal care products (0.42, 95% CI: 0.19, 0.96), rather than household cleaning products (0.79, 95% CI: 0.49, 1.25) and was particularly evident for body lotion (0.12, 95% CI: 0.05, 0.27). Overall usage differed by age (0.64, 95% CI: 0.43, 0.95) but only hand soap and shampoo products differed significantly. “Ever being bothered by fragrance” had no overall association (0.92, 95% CI: 0.65, 1.30) but was associated with laundry detergent use (0.46, 95% CI: 0.23, 0.93). Similarly, black vs. white differences on average were not significant (1.34, 95% CI: 0.55, 3.28) but there were apparent differences in use of shampoo (0.01, 95% CI: 0.00, 0.69), body lotion (4.67, 95% CI: 1.18, 18.47), and perfume (6.22, 95% CI:1.08, 35.89). There was no overall association with thinking about product risks (0.90, 95% CI: 0.79, 1.02), nor with inability to smell HHCB (0.84, 95% CI: 0.63, 1.12). Exposure to fragranced products may differ demographically. The relevance for health disparities should be studied. PMID:25633034

  20. Determinants of exposure to fragranced product chemical mixtures in a sample of twins.

    PubMed

    Gribble, Matthew O; Bandeen-Roche, Karen; Fox, Mary A

    2015-01-27

    Fragranced product chemical mixtures may be relevant for environmental health, but little is known about exposure. We analyzed results from an olfactory challenge with the synthetic musk fragrance 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethyl-cyclopento-γ-2-benzopyran (HHCB), and a questionnaire about attitudes toward chemical safety and use of fragranced products, in a sample of 140 white and 17 black twin pairs attending a festival in Ohio. Data for each product were analyzed using robust ordered logistic regressions with random intercepts for "twin pair" and "sharing address with twin", and fixed effects for sex, age, education, and "ever being bothered by fragrances". Due to the small number of black participants, models were restricted to white participants except when examining racial differences. Overall patterns of association were summarized across product-types through random-effects meta-analysis. Principal components analysis was used to summarize clustering of product use. The dominant axis of variability in fragranced product use was "more vs. less", followed by a distinction between household cleaning products and personal care products. Overall, males used fragranced products less frequently than females (adjusted proportionate odds ratio 0.55, 95% confidence interval 0.33, 0.93). This disparity was driven by personal care products (0.42, 95% CI: 0.19, 0.96), rather than household cleaning products (0.79, 95% CI: 0.49, 1.25) and was particularly evident for body lotion (0.12, 95% CI: 0.05, 0.27). Overall usage differed by age (0.64, 95% CI: 0.43, 0.95) but only hand soap and shampoo products differed significantly. "Ever being bothered by fragrance" had no overall association (0.92, 95% CI: 0.65, 1.30) but was associated with laundry detergent use (0.46, 95% CI: 0.23, 0.93). Similarly, black vs. white differences on average were not significant (1.34, 95% CI: 0.55, 3.28) but there were apparent differences in use of shampoo (0.01, 95% CI: 0.00, 0.69), body lotion (4.67, 95% CI: 1.18, 18.47), and perfume (6.22, 95% CI:1.08, 35.89). There was no overall association with thinking about product risks (0.90, 95% CI: 0.79, 1.02), nor with inability to smell HHCB (0.84, 95% CI: 0.63, 1.12). Exposure to fragranced products may differ demographically. The relevance for health disparities should be studied.

  1. 47 CFR 65.830 - Deducted items.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... taxes (Accounts 4100 and 4340). (2) The interstate portion of customer deposits (Account 4040). (3) The... gains related to sale-leaseback arrangements. (b) The interstate portion of deferred taxes, customer... credits) shall bear the same proportionate relationships as the interstate/intrastate expenses which gave...

  2. Rural Revitalization through Collaboration.

    ERIC Educational Resources Information Center

    Norman, Charles

    In recent years, service programs targeted for Georgia's rural communities have decreased proportionately in relation to those intended for the state's rapidly expanding population centers. At the same time, erosion of traditional manufacturing industries and an adverse agricultural economy have decreased the ability of rural communities to…

  3. [Establishment of cervical vertebral skeletal maturation of female children in Shanghai].

    PubMed

    Sun, Yan; Chen, Rong-jing; Yu, Quan; Fan, Li; Chen, Wei; Shen, Gang

    2009-06-01

    To establish a method for quantitatively evaluating skeletal maturation of cervical vertebrae of female children in Shanghai. The samples were selected from lateral cephalometric radiographs of 240 Shanghai girls, aged 8 to 15 years. The parameters were measured to indicate the morphological changes of the third (C3) and fourth (C4) vertebrae in width, height and the depth of the inferior curvature. The independent-sample t test and stepwise multiple regression analysis were used to estimate the growth status and the ratios of C3, C4 cervical vertebrae by SPSS 15.0 software package. The physical and morphological contour of C3, C4 cervical vertebrae increased proportionately with the increment of age. The regression formula for indicating cervical vertebral skeletal age of female children in Shanghai was expressed by the equation Y= -5.696+8.010 AH3/AP3+6.654 AH3/H3+6.045AH4/PH4 (r=0.912). The regression formula resulted from morphological measurements quantitatively indicates the skeletal maturation of cervical vertebrae of female children in Shanghai.

  4. Iodine Nutritional Status among Adolescent Girls in Uttarakhand, India.

    PubMed

    Kapil, Umesh; Sareen, Neha; Nambiar, Vanisha S; Khenduja, Preetika; Sofi, Nighat Yaseen

    2016-02-01

    Uttarakhand (UK) state is a known endemic region for Iodine deficiency. To assess iodine nutritional status among adolescent girls in districts: Udham Singh Nagar (USN), Nainital (N) and Pauri (P) of UK state. In each district, 30 clusters (schools) were identified by using population proportionate to size cluster sampling. In each school, 60 girls (12-18 years) attending the schools were included. Total of 5430 girls from USN (1823), N (1811) and P (1796) were studied. Clinical examination of thyroid of each girl was conducted. From each cluster, spot urine and salt samples were collected. Total goiter rate was found to be 6.8% (USN), 8.2% (N) and 5.6% (P). Median urinary iodine concentration levels were 250 μg/l (USN), 200 μg/l (N) and 183 μg/l (P). Findings of the study documented that adolescent girls had adequate iodine nutritional status in the three districts of UK. © The Author [2015]. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  5. Methods and analysis of realizing randomized grouping.

    PubMed

    Hu, Liang-Ping; Bao, Xiao-Lei; Wang, Qi

    2011-07-01

    Randomization is one of the four basic principles of research design. The meaning of randomization includes two aspects: one is to randomly select samples from the population, which is known as random sampling; the other is to randomly group all the samples, which is called randomized grouping. Randomized grouping can be subdivided into three categories: completely, stratified and dynamically randomized grouping. This article mainly introduces the steps of complete randomization, the definition of dynamic randomization and the realization of random sampling and grouping by SAS software.

  6. Robust quantum data locking from phase modulation

    NASA Astrophysics Data System (ADS)

    Lupo, Cosmo; Wilde, Mark M.; Lloyd, Seth

    2014-08-01

    Quantum data locking is a uniquely quantum phenomenon that allows a relatively short key of constant size to (un)lock an arbitrarily long message encoded in a quantum state, in such a way that an eavesdropper who measures the state but does not know the key has essentially no information about the message. The application of quantum data locking in cryptography would allow one to overcome the limitations of the one-time pad encryption, which requires the key to have the same length as the message. However, it is known that the strength of quantum data locking is also its Achilles heel, as the leakage of a few bits of the key or the message may in principle allow the eavesdropper to unlock a disproportionate amount of information. In this paper we show that there exist quantum data locking schemes that can be made robust against information leakage by increasing the length of the key by a proportionate amount. This implies that a constant size key can still lock an arbitrarily long message as long as a fraction of it remains secret to the eavesdropper. Moreover, we greatly simplify the structure of the protocol by proving that phase modulation suffices to generate strong locking schemes, paving the way to optical experimental realizations. Also, we show that successful data locking protocols can be constructed using random code words, which very well could be helpful in discovering random codes for data locking over noisy quantum channels.

  7. Using Expert Sources in Breaking Science Stories: A Comparison of Magazine Types.

    ERIC Educational Resources Information Center

    Martin, Shannon E.

    1991-01-01

    Examines the number and kind of sources certain magazines included in articles about science. Finds that science magazines did not use expert sources more often or even carry proportionately more breaking science news than did business and news magazines. (SR)

  8. 7 CFR 966.40 - Expenses.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE TOMATOES GROWN IN FLORIDA Order... share of such expense shall be proportionate to the ratio between the total quantity of tomatoes handled by him as the first handler thereof during a fiscal period and the total quantity of tomatoes handled...

  9. Vision, Educational Level, and Empowering Work Relationships.

    ERIC Educational Resources Information Center

    Johnson, G. M.

    1995-01-01

    Thirty-one machinists (blind, sighted, and visually impaired) answered questions about trust, resource sharing, and empowerment in work relationships. Employees with low vision were the least trusting and trusted, received the fewest shared resources, and reported proportionately more disempowering relationships. More educated employees saw more…

  10. The Middle Income Squeeze

    ERIC Educational Resources Information Center

    Glover, Steve

    1978-01-01

    Complaints about a middle income family's hardships in sending their children to private colleges and universities are examined. The difficulty may be attributable to a progressive College Scholarship Service (CSS) taxation rate schedule that causes larger proportionate reductions in the standard of living for some families than others.…

  11. Workplace discrimination and cumulative trauma disorders: the national EEOC ADA research project.

    PubMed

    Armstrong, Amy J; McMahon, Brian T; West, Steven L; Lewis, Allen

    2005-01-01

    Employment discrimination of persons with cumulative trauma disorders (CTDs) was explored using the Integrated Mission System dataset of the US Equal Employment Opportunity Commission. Demographic characteristics and merit resolutions of the Charging Parties (persons with CTD) were compared to individuals experiencing other physical, sensory and neurological impairments. Factors compared also included industry designation, geographic region, and size of Respondents against which allegations were filed. Persons with CTD had proportionately greater allegations among large Respondents (greater than 500 workers) engaged in manufacturing, utilities, transportation, finance insurance and real estate. The types of discrimination Issues that were proportionately greater in the CTD group included layoff, failure to reinstate, and failure to provide reasonable accommodation. The CTD group was significantly less likely than the comparison group to be involved in discrimination Issues such as assignment to less desirable duty, shift or work location; demotion; termination, or failure to hire or provide training. Persons with CTD had higher proportions of merit Resolutions where allegations were voluntarily withdrawn by the Charging Party with benefits.

  12. [Krigle estimation and its simulated sampling of Chilo suppressalis population density].

    PubMed

    Yuan, Zheming; Bai, Lianyang; Wang, Kuiwu; Hu, Xiangyue

    2004-07-01

    In order to draw up a rational sampling plan for the larvae population of Chilo suppressalis, an original population and its two derivative populations, random population and sequence population, were sampled and compared with random sampling, gap-range-random sampling, and a new systematic sampling integrated Krigle interpolation and random original position. As for the original population whose distribution was up to aggregative and dependence range in line direction was 115 cm (6.9 units), gap-range-random sampling in line direction was more precise than random sampling. Distinguishing the population pattern correctly is the key to get a better precision. Gap-range-random sampling and random sampling are fit for aggregated population and random population, respectively, but both of them are difficult to apply in practice. Therefore, a new systematic sampling named as Krigle sample (n = 441) was developed to estimate the density of partial sample (partial estimation, n = 441) and population (overall estimation, N = 1500). As for original population, the estimated precision of Krigle sample to partial sample and population was better than that of investigation sample. With the increase of the aggregation intensity of population, Krigel sample was more effective than investigation sample in both partial estimation and overall estimation in the appropriate sampling gap according to the dependence range.

  13. Differentially Private Frequent Sequence Mining via Sampling-based Candidate Pruning

    PubMed Central

    Xu, Shengzhi; Cheng, Xiang; Li, Zhengyi; Xiong, Li

    2016-01-01

    In this paper, we study the problem of mining frequent sequences under the rigorous differential privacy model. We explore the possibility of designing a differentially private frequent sequence mining (FSM) algorithm which can achieve both high data utility and a high degree of privacy. We found, in differentially private FSM, the amount of required noise is proportionate to the number of candidate sequences. If we could effectively reduce the number of unpromising candidate sequences, the utility and privacy tradeoff can be significantly improved. To this end, by leveraging a sampling-based candidate pruning technique, we propose a novel differentially private FSM algorithm, which is referred to as PFS2. The core of our algorithm is to utilize sample databases to further prune the candidate sequences generated based on the downward closure property. In particular, we use the noisy local support of candidate sequences in the sample databases to estimate which sequences are potentially frequent. To improve the accuracy of such private estimations, a sequence shrinking method is proposed to enforce the length constraint on the sample databases. Moreover, to decrease the probability of misestimating frequent sequences as infrequent, a threshold relaxation method is proposed to relax the user-specified threshold for the sample databases. Through formal privacy analysis, we show that our PFS2 algorithm is ε-differentially private. Extensive experiments on real datasets illustrate that our PFS2 algorithm can privately find frequent sequences with high accuracy. PMID:26973430

  14. Systematic versus random sampling in stereological studies.

    PubMed

    West, Mark J

    2012-12-01

    The sampling that takes place at all levels of an experimental design must be random if the estimate is to be unbiased in a statistical sense. There are two fundamental ways by which one can make a random sample of the sections and positions to be probed on the sections. Using a card-sampling analogy, one can pick any card at all out of a deck of cards. This is referred to as independent random sampling because the sampling of any one card is made without reference to the position of the other cards. The other approach to obtaining a random sample would be to pick a card within a set number of cards and others at equal intervals within the deck. Systematic sampling along one axis of many biological structures is more efficient than random sampling, because most biological structures are not randomly organized. This article discusses the merits of systematic versus random sampling in stereological studies.

  15. Prevalence and treatment gap in childhood epilepsy in a north Indian city: a community-based study.

    PubMed

    Pandey, Swati; Singhi, Pratibha; Bharti, Bhavneet

    2014-04-01

    Epilepsy is one of the most common neurological disorders prevalent in childhood period. There is scarcity of epidemiological data, required to plan services in resource constrained developing nations. To study the prevalence and treatment gap in childhood epilepsy in north Indian city, in the age group of 1-18 years. A two stage stratified cluster sampling; probability proportionate to size (PPS) was employed. A ten question screening questionnaire was employed to identify the presence of epilepsy. Definitions provided by International League against Epilepsy (ILAE) were used to classify screen positive subjects as epilepsy and to calculate the treatment gap. The prevalence rate for epilepsy was 6.24/1000 population. Febrile seizures and neurocysticercosis were most common causes of symptomatic seizures in childhood. This study of epidemiology of epilepsy provides valuable aid in optimizing effective community approach, thereby improving outcomes of childhood epilepsy.

  16. Microgravity Smoldering Combustion on the USML-1 Space Shuttle Mission

    NASA Technical Reports Server (NTRS)

    Stocker, Dennis P.; Olson, Sandra L.; Torero, Jose L.; Fernandez-Pello, A Carlos

    1994-01-01

    Preliminary results from an experimental study of the smolder characteristics of a porous combustible material (flexible polyurethane foam) in normal and microgravity are presented. The experiments, limited in fuel sample size and power available for ignition, show that the smolder process was primarily controlled by heat losses from the reaction to the surrounding environment. In microgravity, the reduced heat losses due to the absence of natural convection result in only slightly higher temperatures in the quiescent microgravity test than in normal gravity but a dramatically larger production of combustion products in all microgravity tests. Particularly significant is the proportionately larger amount of carbon monoxide and light organic compounds produced in microgravity, despite comparable temperatures and similar char patterns. This excessive production of fuel-rich combustion products may be a generic characteristic of smoldering polyurethane in microgravity, with an associated increase in the toxic hazard of smolder in spacecraft.

  17. Microgravity smoldering combustion on the USML-1 Space Shuttle mission

    NASA Technical Reports Server (NTRS)

    Stocker, Dennis P.; Olson, Sandra L.; Torero, Jose L.; Fernandez-Pello, A. Carlos

    1995-01-01

    Preliminary results from an experimental study of the smolder characteristics of a porous combustible material (flexible polyurethane foam) in normal and microgravity are presented. The experiments, limited in fuel sample size and power available for ignition, show that the smolder process was primarily controlled by heat losses from the reaction to the surrounding environment In microgravity, the reduced heat losses due to the absence of natural convection result in only slightly higher temperatures in the quiescent microgravity test than in normal gravity, but a dramatically larger production of combustion products in all microgravity tests. Particularly significant is the proportionately larger amount of carbon monoxide and light organic compounds produced in microgravity, despite comparable temperatures and similar char patterns. This excessive production of fuel-rich combustion products may be a generic characteristic of smoldering polyurethane in microgravity, with an associated increase in the toxic hazard of smolder in spacecraft.

  18. Predicting long-term citation impact of articles in social and personality psychology.

    PubMed

    Haslam, Nick; Koval, Peter

    2010-06-01

    The citation impact of a comprehensive sample of articles published in social and personality psychology journals in 1998 was evaluated. Potential predictors of the 10-yr. citation impact of 1580 articles from 37 journals were investigated, including number of authors, number of references, journal impact factor, author nationality, and article length, using linear regression. The impact factor of the journal in which articles appeared was the primary predictor of the citations that they accrued, accounting for 30% of the total variance. Articles with greater length, more references, and more authors were cited relatively often, although the citation advantage of longer articles was not proportionate to their length. A citation advantage was also enjoyed by authors from the United States of America, Canada, and the United Kingdom. 37% of the variance in the total number of citations was accounted for by the study variables.

  19. 31 CFR 50.50 - Federal share of compensation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Section 50.50 Money and Finance: Treasury Office of the Secretary of the Treasury TERRORISM RISK INSURANCE... Federal share of compensation will be paid by Treasury unless the aggregate industry insured losses... insurer's proportionate share of insured losses from a State residual market insurance entity or State...

  20. Non-dermatological complications and genetic aspects of the Rothmund-Thomson syndrome.

    PubMed

    Starr, D G; McClure, J P; Connor, J M

    1985-01-01

    We report two new cases of Rothmund-Thomson syndrome which emphasize the less well-known non-dermatological complications, namely: hypodontia, soft tissue contractures, proportionate short stature, hypogonadism, anaemia and osteogenic sarcoma. Genetic analysis of these and previously reported pedigrees supports autosomal recessive inheritance.

  1. 7 CFR 1709.112 - Ineligible grant purposes.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... target community's proportionate share of a larger energy project. (c) Grant funds may not be used to... AGRICULTURE ASSISTANCE TO HIGH ENERGY COST COMMUNITIES RUS High Energy Cost Grant Program § 1709.112..., structures or real property not directly associated with providing energy services in the target community...

  2. 7 CFR 1709.112 - Ineligible grant purposes.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... target community's proportionate share of a larger energy project. (c) Grant funds may not be used to... AGRICULTURE ASSISTANCE TO HIGH ENERGY COST COMMUNITIES RUS High Energy Cost Grant Program § 1709.112..., structures or real property not directly associated with providing energy services in the target community...

  3. 7 CFR 1709.112 - Ineligible grant purposes.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... target community's proportionate share of a larger energy project. (c) Grant funds may not be used to... AGRICULTURE ASSISTANCE TO HIGH ENERGY COST COMMUNITIES RUS High Energy Cost Grant Program § 1709.112..., structures or real property not directly associated with providing energy services in the target community...

  4. 7 CFR 1709.112 - Ineligible grant purposes.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... target community's proportionate share of a larger energy project. (c) Grant funds may not be used to... AGRICULTURE ASSISTANCE TO HIGH ENERGY COST COMMUNITIES RUS High Energy Cost Grant Program § 1709.112..., structures or real property not directly associated with providing energy services in the target community...

  5. 7 CFR 1709.112 - Ineligible grant purposes.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... target community's proportionate share of a larger energy project. (c) Grant funds may not be used to... AGRICULTURE ASSISTANCE TO HIGH ENERGY COST COMMUNITIES RUS High Energy Cost Grant Program § 1709.112..., structures or real property not directly associated with providing energy services in the target community...

  6. Dual wire weld feed proportioner

    NASA Technical Reports Server (NTRS)

    Nugent, R. E.

    1968-01-01

    Dual feed mechanism enables proportioning of two different weld feed wires during automated TIG welding to produce a weld alloy deposit of the desired composition. The wires are fed into the weld simultaneously. The relative feed rates of the wires and the wire diameters determine the weld deposit composition.

  7. Improved Compressive Sensing of Natural Scenes Using Localized Random Sampling

    PubMed Central

    Barranca, Victor J.; Kovačič, Gregor; Zhou, Douglas; Cai, David

    2016-01-01

    Compressive sensing (CS) theory demonstrates that by using uniformly-random sampling, rather than uniformly-spaced sampling, higher quality image reconstructions are often achievable. Considering that the structure of sampling protocols has such a profound impact on the quality of image reconstructions, we formulate a new sampling scheme motivated by physiological receptive field structure, localized random sampling, which yields significantly improved CS image reconstructions. For each set of localized image measurements, our sampling method first randomly selects an image pixel and then measures its nearby pixels with probability depending on their distance from the initially selected pixel. We compare the uniformly-random and localized random sampling methods over a large space of sampling parameters, and show that, for the optimal parameter choices, higher quality image reconstructions can be consistently obtained by using localized random sampling. In addition, we argue that the localized random CS optimal parameter choice is stable with respect to diverse natural images, and scales with the number of samples used for reconstruction. We expect that the localized random sampling protocol helps to explain the evolutionarily advantageous nature of receptive field structure in visual systems and suggests several future research areas in CS theory and its application to brain imaging. PMID:27555464

  8. Intimate Partner Femicide in South Africa in 1999 and 2009

    PubMed Central

    Abrahams, Naeemah; Mathews, Shanaaz; Martin, Lorna J.; Lombard, Carl; Jewkes, Rachel

    2013-01-01

    Background Death is the most extreme consequence of intimate partner violence. Female homicide studies with data on the perpetrator–victim relationship can provide insights. We compare the results of two South African national studies of female homicide with similar sampling done 10 y apart. Methods and Findings We conducted a retrospective national survey using a weighted cluster design of a proportionate random sample of 38 mortuaries to identify homicides committed in 2009. We abstracted victim data from mortuary and autopsy reports, and perpetrator data from police interviews. We compared homicides of women 14 y and older in 2009 with previously published data collected with the same methodology for homicides committed in 1999. The study found that the rate of female homicide per 100,000 female population in 2009 was 12.9 (95% confidence interval [CI]: 9.3, 16.5), compared to 24.7 (95% CI: 17.7, 31.6) in 1999. The incidence rate ratio of 0.54 (95% CI: 0.20, 0.84) reflects a significantly lower rate in 2009. The rate of intimate partner femicide was 5.6/100,000 in 2009 versus 8.8/100,000 in 1999, with an incidence rate ratio of 0.63 (95% CI: 0.24, 1.02), indicating no difference between rates. Logistic regression analysis of homicide characteristics showed that the odds ratio of suspected rape among non-intimate femicides in 2009 compared to 1999 was 2.61 (95% CI: 1.23, 4.08) and among intimate partner femicides it was 0.84 (95% CI: 0.50, 1.42). The OR of homicide by gunshot was 0.54 (95% CI: 0.30, 0.99) in 2009 versus 1999. There was a significant drop in convictions of perpetrators of non-intimate femicide in 2009 versus 1999 (OR = 0.32 [95% CI: 0.19, 0.53]). Limitations of the study include the relatively small sample size and having only two time points. Conclusions Female homicide in South Africa was lower in 2009 than 1999, but intimate partner femicide and suspected rape homicide rates were not statistically different. The cause of the difference is unknown. The findings suggest that South Africa needs greater efforts nationally to implement evidence-based violence prevention. Please see later in the article for the Editors' Summary PMID:23565064

  9. What's for lunch? An analysis of lunch menus in 83 urban and rural Oklahoma child-care centers providing all-day care to preschool children.

    PubMed

    Frampton, Ashley M; Sisson, Susan B; Horm, Diane; Campbell, Janis E; Lora, Karina; Ladner, Jennifer L

    2014-09-01

    More than half of 3- to 6-year-old children attend child-care centers. Dietary intakes of children attending child-care centers tend to fall short of Dietary Reference Intakes (DRIs). Our aim was to examine macro-/micronutrient content of child-care center menus, compare menus to one third of DRIs, and determine menu differences by population density. A stratified, random, geographically proportionate sample of Oklahoma child-care centers was obtained. Child-care centers providing all-day care for 2- to 5-year-old children were contacted to complete a telephone questionnaire and asked to send in that month's menus for the 3- to 4-year-old children. Overall means and standard deviations of the nutrient content of 5 days of lunch menus were calculated. Comparisons were made to both the 1- to 3-year-old and 4- to 8-year-old DRIs. One-sample t tests compared mean nutrient content of lunches to one third of the DRIs for the overall sample and urban/rural classification. Independent t tests compared nutrient content of urban and rural lunches. One hundred sixty-seven child-care centers were contacted; 83 completed the study (50% response). Menus provided statistically significantly insufficient carbohydrate, dietary fiber, iron, vitamin D, and vitamin E. Calcium was higher than the 1- to 3-year-old DRI, but lower than the 4- to 8-year-old DRI. Folate was higher than the 1- to 3-year-old DRI, but not different from the 4- to 8-year-old DRI. Sodium was higher than the DRI for both age groups. Thirty-four child-care centers (41%) were classified as urban and 49 (59%) as rural. Urban menus provided less than the 4- to 8-year-old DRI for folate, but rural child-care center menus did not. Oklahoma child-care center menus appear to provide adequate protein, magnesium, zinc, vitamin A, and vitamin C, but may be deficient in key nutrients required for good health and proper development in preschool-aged children. These issues can be addressed by including food and nutrition practitioners in the process to ensure child-care center menus are a useful resource and nutritionally appropriate for preschool children. Copyright © 2014 Academy of Nutrition and Dietetics. Published by Elsevier Inc. All rights reserved.

  10. Evaluation of nationwide supplementary immunization in Lao People's Democratic Republic: Population-based seroprevalence survey of anti-measles and anti-rubella IgG in children and adults, mathematical modelling and a stability testing of the vaccine

    PubMed Central

    Miyano, Shinsuke; Mori, Yoshio; Vynnycky, Emilia; Keungsaneth, Phath; Vongphrachanh, Phengta; Xeuatvongsa, Anonh; Sisouk, Thongchanh; Som-Oulay, Vilasak; Khamphaphongphane, Bouaphan; Sengkeopaseuth, Bounthanom; Pathammavong, Chansay; Phounphenghak, Kongxay; Kitamura, Tomomi; Takeda, Makoto; Komase, Katsuhiro

    2018-01-01

    Background Measles outbreaks have occurred in some countries despite supplementary immunization activities (SIA) using measles-containing vaccine with high vaccination coverage. We conducted a cross-sectional seroprevalence survey to estimate population immunity in Lao People's Democratic Republic where repeated mass immunization has failed to eliminate measles. Methods and findings In this nationwide multistage cluster sampling survey conducted in 2014 based on probability proportionate to size sampling, blood samples were collected from 2,135 children and adults living in 52 randomly selected villages. Anti-measles and anti-rubella IgG were measured, and IgG prevalence was calculated. We applied mathematical modelling to estimate the number of cases of congenital rubella syndrome (CRS) in 2013 that were averted by the 2011 SIA. A stability testing was applied to the MR vaccine at 4°C, 25°C, and 35°C to examine stability differences between measles and rubella vaccine components. Measles IgG prevalence was significantly lower in the target age groups (5–21 years) of the 2011 SIA using a combination vaccine for measles and rubella vaccine (MR vaccine) than in young adults (22–39 years) (86.8% [95% CI: 83.0–90.6] vs. 99.0% [98.3–99.8]; p<0.001), whereas rubella IgG prevalence was significantly higher (88.2% [84.5–91.8] vs. 74.6% [70.7–78.5]; p<0.001). In the SIA target age groups, prevalence of measles IgG, but not rubella IgG, increased with age. CRS cases prevented in 2013 ranged from 16 [0–50] to 92 [32–180] if the force of infection had remained unchanged or had been reduced by 75%, respectively. In freeze-dried conditions, the measles vaccine component was more heat sensitive than the rubella component. Conclusions Inconsistent IgG prevalence between measles and rubella in Lao PDR can be partly explained by different stability of the measles and rubella vaccine components under heat exposure. Suboptimal vaccine handling may cause insufficient immunogenicity for measles, which subsequently leads to an outbreak despite high SIA coverage, while direct evidence is lacking. Temperature monitoring of the vaccine should be conducted. PMID:29596472

  11. Evaluation of nationwide supplementary immunization in Lao People's Democratic Republic: Population-based seroprevalence survey of anti-measles and anti-rubella IgG in children and adults, mathematical modelling and a stability testing of the vaccine.

    PubMed

    Hachiya, Masahiko; Miyano, Shinsuke; Mori, Yoshio; Vynnycky, Emilia; Keungsaneth, Phath; Vongphrachanh, Phengta; Xeuatvongsa, Anonh; Sisouk, Thongchanh; Som-Oulay, Vilasak; Khamphaphongphane, Bouaphan; Sengkeopaseuth, Bounthanom; Pathammavong, Chansay; Phounphenghak, Kongxay; Kitamura, Tomomi; Takeda, Makoto; Komase, Katsuhiro

    2018-01-01

    Measles outbreaks have occurred in some countries despite supplementary immunization activities (SIA) using measles-containing vaccine with high vaccination coverage. We conducted a cross-sectional seroprevalence survey to estimate population immunity in Lao People's Democratic Republic where repeated mass immunization has failed to eliminate measles. In this nationwide multistage cluster sampling survey conducted in 2014 based on probability proportionate to size sampling, blood samples were collected from 2,135 children and adults living in 52 randomly selected villages. Anti-measles and anti-rubella IgG were measured, and IgG prevalence was calculated. We applied mathematical modelling to estimate the number of cases of congenital rubella syndrome (CRS) in 2013 that were averted by the 2011 SIA. A stability testing was applied to the MR vaccine at 4°C, 25°C, and 35°C to examine stability differences between measles and rubella vaccine components. Measles IgG prevalence was significantly lower in the target age groups (5-21 years) of the 2011 SIA using a combination vaccine for measles and rubella vaccine (MR vaccine) than in young adults (22-39 years) (86.8% [95% CI: 83.0-90.6] vs. 99.0% [98.3-99.8]; p<0.001), whereas rubella IgG prevalence was significantly higher (88.2% [84.5-91.8] vs. 74.6% [70.7-78.5]; p<0.001). In the SIA target age groups, prevalence of measles IgG, but not rubella IgG, increased with age. CRS cases prevented in 2013 ranged from 16 [0-50] to 92 [32-180] if the force of infection had remained unchanged or had been reduced by 75%, respectively. In freeze-dried conditions, the measles vaccine component was more heat sensitive than the rubella component. Inconsistent IgG prevalence between measles and rubella in Lao PDR can be partly explained by different stability of the measles and rubella vaccine components under heat exposure. Suboptimal vaccine handling may cause insufficient immunogenicity for measles, which subsequently leads to an outbreak despite high SIA coverage, while direct evidence is lacking. Temperature monitoring of the vaccine should be conducted.

  12. The structured ancestral selection graph and the many-demes limit.

    PubMed

    Slade, Paul F; Wakeley, John

    2005-02-01

    We show that the unstructured ancestral selection graph applies to part of the history of a sample from a population structured by restricted migration among subpopulations, or demes. The result holds in the limit as the number of demes tends to infinity with proportionately weak selection, and we have also made the assumptions of island-type migration and that demes are equivalent in size. After an instantaneous sample-size adjustment, this structured ancestral selection graph converges to an unstructured ancestral selection graph with a mutation parameter that depends inversely on the migration rate. In contrast, the selection parameter for the population is independent of the migration rate and is identical to the selection parameter in an unstructured population. We show analytically that estimators of the migration rate, based on pairwise sequence differences, derived under the assumption of neutrality should perform equally well in the presence of weak selection. We also modify an algorithm for simulating genealogies conditional on the frequencies of two selected alleles in a sample. This permits efficient simulation of stronger selection than was previously possible. Using this new algorithm, we simulate gene genealogies under the many-demes ancestral selection graph and identify some situations in which migration has a strong effect on the time to the most recent common ancestor of the sample. We find that a similar effect also increases the sensitivity of the genealogy to selection.

  13. Minnesota wolf ear lengths as possible indicators of taxonomic differences

    USGS Publications Warehouse

    Mech, L. David

    2011-01-01

    Genetic findings suggest that 2 types of wolves, Canis lupus (Gray Wolf) and C. lycaon (Eastern Wolf), and/or their hybrids occupy Minnesota (MN), and this study examines adult wolf ear lengths as a possible distinguisher between these two. Photographic evidence suggested that the Eastern Wolf possesses proportionately longer ears than Gray Wolves. Ear lengths from 22 northwestern MN wolves from the early 1970s and 22 Alaskan wolves were used to represent Gray Wolves, and the greatest length of the sample (12.8 cm) was used as the least length to demarcate Eastern Wolf from Gray Wolf influence in the samples. Twenty-three percent of 112 adult wolves from Algonquin Park in eastern Ontario and 30% of 106 recent adult wolves in northeastern MN possessed ears >12.8 cm. The northeastern MN sample differed significantly from that of current and past northwestern MN wolves. Ear-lengths of wolves in the eastern half of the northeastern MN wolf population were significantly longer than those in the western half of that study area, even though the mean distance between the 2 areas was only 40 km, and the mean length of my 2004–2009 sample was significantly longer than that of 1999–2003. These findings support the hypothesis that Eastern Wolves tend to possess longer ears than do Gray Wolves and suggest a dynamic hybridization process is still underway in MN.

  14. Development of the SaFETy Score: A Clinical Screening Tool for Predicting Future Firearm Violence Risk

    PubMed Central

    Goldstick, Jason E.; Carter, Patrick M.; Walton, Maureen A.; Dahlberg, Linda L.; Sumner, Steven A.; Zimmerman, Marc A.; Cunningham, Rebecca M.

    2017-01-01

    Background Interpersonal firearm violence among youth is a substantial public health problem, and emergency department (ED) physicians require a clinical screening tool to identify high-risk youth. Objective To derive a clinically feasible risk index for firearm violence. Design 24-month prospective cohort study. Setting Urban, level 1 ED. Participants Substance-using youths, aged 14 to 24 years, seeking ED care for an assault-related injury and a proportionately sampled group of non–assault-injured youth enrolled from September 2009 through December 2011. Measurements Firearm violence (victimization/perpetration) and validated questionnaire items. Results A total of 599 youths were enrolled, and presence/absence of future firearm violence during follow-up could be ascertained in 483 (52.2% were positive). The sample was randomly split into training (75%) and post–score-construction validation (25%) sets. Using elastic-net penalized logistic regression, 118 baseline predictors were jointly analyzed; the most predictive variables fell predominantly into 4 domains: violence victimization, community exposure, peer influences, and fighting. By selection of 1 item from each domain, the 10-point SaFETy (Serious fighting, Friend weapon carrying, community Environment, and firearm Threats) score was derived. SaFETy was associated with firearm violence in the validation set (odds ratio [OR], 1.47 [95% CI, 1.23 to 1.79]); this association remained (OR, 1.44 [CI, 1.20 to 1.76]) after adjustment for reason for ED visit. In 5 risk strata observed in the training data, firearm violence rates in the validation set were 18.2% (2 of 11), 40.0% (18 of 45), 55.8% (24 of 43), 81.3% (13 of 16), and 100.0% (6 of 6), respectively. Limitations The study was conducted in a single ED and involved substance-using youths. SaFETy was not externally validated. Conclusion The SaFETy score is a 4-item score based on clinically feasible questionnaire items and is associated with firearm violence. Although broader validation is required, SaFETy shows potential to guide resource allocation for prevention of firearm violence. Primary Funding Source National Institute on Drug Abuse R01024646. PMID:28395357

  15. Disability and access to health care - a community based descriptive study.

    PubMed

    Maart, Soraya; Jelsma, Jennifer

    2014-01-01

    The World Disability Report highlighted the need for adequate access to health and medical rehabilitation services for those with disability. Participants in a large community based survey in a low-income area were asked questions relating to their use of health related services. Using random, cluster sampling a representative sample of 1083 households in a deprived area of Cape Town were approached and 152 people with disability were interviewed. Those with disability were more likely to be male (χ² = 4.24, p = 0.03) and unemployed (χ² = 66.89, p > 0.001) compared to those without disability. The percentages reporting unmet needs were respectively: 54% for home-based care; 34.5% for assistive devices, 28.9% for medical rehabilitation services; and 2.5% for health services. Those over 65 years of age were less likely to have had the medical rehabilitation that they required (χ² = 8.00, p = 0.018). There were fewer respondents with sensory and language disorders but these groups reported proportionately more unmet needs. The main problems with accessing services included inadequate finances (71%) and transport problems (72%). It is recommended that all efforts be expended to extend appropriate rehabilitation services, including home based-care and appliances to those identified as having disability, particularly to those older than 65 years. In addition, the services need to be affordable and accessible in terms of suitable transport, particularly in the light of the high unemployment rate and the large number of respondents with mobility problems. Implications for Rehabilitation People with disability may be the most in need of additional health related care and the least able to access it. Transport and financial considerations were found to limit the ability to access appropriate care. Rehabilitation and health services need to reach out through home-based care and appropriate forms of rehabilitation delivery to ensure that those who are most in need of care, such as the elderly and those with more neglected forms of disability, are provided with the services that they require.

  16. 25 CFR 152.31 - Cost of conveyance; payment.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Cost of conveyance; payment. 152.31 Section 152.31 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER ISSUANCE OF PATENTS IN FEE... such costs, the collection of the proportionate share from the tribe may be waived. ...

  17. Sex, Salaries, and Library Support--1981.

    ERIC Educational Resources Information Center

    Heim, Kathleen M.; Kacena, Carolyn

    1981-01-01

    Notes that library support kept pace with inflation during 1980 and indicates a continuing sex bias with respect to women library directors. Women are neither proportionately represented nor paid as well as their male counterparts and their libraries suffer from lower per capita financial support. Data and references are provided. (RAA)

  18. The 3-M syndrome. A heritable low birthweight dwarfism.

    PubMed

    Van Goethem, H; Malvaux, P

    1987-10-01

    Two male siblings and one girl with the 3-M syndrome are reported. The main clinical features include low birthweight, proportionate dwarfism, hatched-shaped cranio-facial configuration, abnormalities of mouth and teeth, short broad neck with prominent trapezius, pectus deformity, transverse grooves of anterior chest, and winged scapulae.

  19. 29 CFR 541.602 - Salary basis.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... takes unpaid leave under the Family and Medical Leave Act. Rather, when an exempt employee takes unpaid leave under the Family and Medical Leave Act, an employer may pay a proportionate part of the full... four hours of unpaid leave under the Family and Medical Leave Act, the employer could deduct 10 percent...

  20. 76 FR 28696 - Periodic Reporting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-18

    ... for Priority mailpieces; 2. The inclusion of D-Report adjustments; \\3\\ \\3\\ The D-Report is one of six.... Since the D- Report adjustment is computed as a cost per piece, it contends, ``Other'' costs should be distributed on a per-piece basis, rather than treated as proportionate to mail processing, transportation, and...

  1. New Directions for Black Women?

    ERIC Educational Resources Information Center

    McGuigan, Dorothy, Ed.

    1978-01-01

    This collection of papers deals with various aspects of the black female experience in America. "The Black Woman in Transition" discusses the effects of sexism and racism on black women with particular reference to employment and education; it is noted that black women, in comparison with other groups in society, suffer a proportionately higher…

  2. Do Lifestyles Shape Self-Regulated Learning Strategies?

    ERIC Educational Resources Information Center

    Tezci, Erdogan; Sezer, Fahri; Aktan, Sumer; Gurgan, Ugur

    2016-01-01

    Problem Statement: Being a virtuous citizen, developing communication skills, and becoming a life-long learner are directly proportionate to the individuals' perspectives on life. Provided that an education system is able to positively change the individuals' perspectives on life, it may allow individuals to acquire terminal behaviors easier. This…

  3. A Web-Based Virtual Classroom System Model

    ERIC Educational Resources Information Center

    Adewale, Olumide S.; Ibam, Emmanuel O.; Alese, B. K.

    2012-01-01

    The population of students all over the world is growing without a proportionate increase in teaching/learning resources/infrastructure. There is also much quest for learning in an environment that provides equal opportunities to all learners. The need to provide an equal opportunity learning environment that will hitherto improve the system of…

  4. 26 CFR 1.853-1 - Foreign tax credit allowed to shareholders.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Regulated Investment Companies and Real Estate Investment... regulated investment company, meeting the requirements set forth in section 853(a) and paragraph (b) of this... investment company shall apply their proportionate share of such foreign taxes paid, or deemed to have been...

  5. 26 CFR 1.853-1 - Foreign tax credit allowed to shareholders.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Regulated Investment Companies and Real Estate Investment... regulated investment company, meeting the requirements set forth in section 853(a) and paragraph (b) of this... investment company shall apply their proportionate share of such foreign taxes paid, or deemed to have been...

  6. 26 CFR 1.853-1 - Foreign tax credit allowed to shareholders.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Regulated Investment Companies and Real Estate Investment... regulated investment company, meeting the requirements set forth in section 853(a) and paragraph (b) of this... investment company shall apply their proportionate share of such foreign taxes paid, or deemed to have been...

  7. 26 CFR 1.853-1 - Foreign tax credit allowed to shareholders.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Regulated Investment Companies and Real Estate Investment... regulated investment company, meeting the requirements set forth in section 853(a) and paragraph (b) of this... investment company shall apply their proportionate share of such foreign taxes paid, or deemed to have been...

  8. Stressful Psychosocial Work Environment, Poor Sleep, and Depressive Symptoms among Primary School Teachers

    ERIC Educational Resources Information Center

    Gluschkoff, Kia; Elovainio, Marko; Keltikangas-Järvinen, Liisa; Hintsanen, Mirka; Mullola, Sari; Hintsa, Taina

    2016-01-01

    Introduction: We examined the associations and proportionate contributions of three well-validated models of stressful psychosocial work environment (job strain, effort-reward imbalance, and organizational injustice) in explaining depressive symptoms among primary school teachers. In addition, we tested the mediating role of different types of…

  9. 31 CFR 205.33 - How are funds transfers processed?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... needed by the State and must time the disbursement to be in accord with the actual, immediate cash... funds transfers must be as close as is administratively feasible to a State's actual cash outlay for direct program costs and the proportionate share of any allowable indirect costs. States should exercise...

  10. 30 CFR 202.151 - Royalty on processed gas.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... residue gas shall be allowed royalty free for operation of the processing plant, but no allowance shall be... that proportionate share of each lease's residue gas necessary for the operation of the processing... resulting from processing gas, which is reinjected into a reservoir within the same lease, unit area, or...

  11. A Problem-Solving Analysis of Women in Debate.

    ERIC Educational Resources Information Center

    Haffey, Deborah Bush

    The number of women participating in intercollegiate debate is proportionately lower than their representation on campuses. Furthermore, women's rate of success at the highest level of the Cross Examination Debate Association national competition is far lower than their representation in the organization. However, as women enter fields such as…

  12. 26 CFR 1.883-4 - Qualified shareholder stock ownership test.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... proportionate interest rules of this paragraph (c) shall apply successively upward through the chain of... in the chain of ownership to satisfy one of the stock ownership tests, the foreign corporation must... intermediary in the chain of ownership between that person and the foreign corporation seeking qualified...

  13. 26 CFR 1.883-4 - Qualified shareholder stock ownership test.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... proportionate interest rules of this paragraph (c) shall apply successively upward through the chain of... in the chain of ownership to satisfy one of the stock ownership tests, the foreign corporation must... intermediary in the chain of ownership between that person and the foreign corporation seeking qualified...

  14. 26 CFR 1.883-4 - Qualified shareholder stock ownership test.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... proportionate interest rules of this paragraph (c) shall apply successively upward through the chain of... in the chain of ownership to satisfy one of the stock ownership tests, the foreign corporation must... intermediary in the chain of ownership between that person and the foreign corporation seeking qualified...

  15. 26 CFR 1.883-4 - Qualified shareholder stock ownership test.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... proportionate interest rules of this paragraph (c) shall apply successively upward through a chain of ownership... (including mere legal owners or recordholders acting as nominees), each intermediary in the chain of... chain of ownership through which the individual owns stock in the corporation seeking qualified foreign...

  16. 26 CFR 1.883-4 - Qualified shareholder stock ownership test.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... proportionate interest rules of this paragraph (c) shall apply successively upward through the chain of... in the chain of ownership to satisfy one of the stock ownership tests, the foreign corporation must... intermediary in the chain of ownership between that person and the foreign corporation seeking qualified...

  17. Meeting Peace Operations’ Requirements While Maintaining MTW Readiness

    DTIC Science & Technology

    1998-01-01

    in Somalia were issued cayenne pepper spray as an effective means of proportionate force against low-level threats... In one instance, a Somali...called for, but the Marines saw cayenne pepper spray as a substitute for deadly force, instead of as a complement.26 To better train his junior

  18. Concurrent central diabetes insipidus and panhypopituitarism in a German shepherd dog.

    PubMed

    Ramsey, I K; Dennis, R; Herrtage, M E

    1999-06-01

    This report describes a German shepherd dog that was presented with proportionate dwarfism and coat changes typical of hypopituitarism but that was also profoundly polydipsic and polyuric. Investigations established a diagnosis of concurrent central diabetes insipidus. Treatment with desmopressin was successful in managing the polyuria and polydipsia.

  19. Immunoreactive LH in long-term frozen human urine samples.

    PubMed

    Singh, Gurmeet Kaur Surindar; Jimenez, Mark; Newman, Ron; Handelsman, David J

    2014-04-01

    Urine provides a convenient non-invasive alternative to blood sampling for measurement of certain hormones. Urinary luteinizing hormone (LH) measurements have been used for endocrinology research and anti-doping testing. However, the commercially available LH immunoassays are developed and validated for human blood samples but not urine so that LH assays intended for use with urine samples need thorough validation. Therefore, the present study evaluated the measurement of urinary LH immunoreactivity using previously validated immunofluorometric (IF) and immunochemiluminometric (ICL) LH assays after prolonged frozen storage. LH was measured in serial urine samples following administration of a single injection of one of two doses of recombinant human chorionic hormone (rhCG) with assays run at the end of study (2008) and again after four years of frozen (-20 °C) storage where samples were stored without adding preservatives. The ICL assay showed quantitatively reproducible LH measurements after prolonged -20 °C storage. However, the IF immunoassay gave consistently lower LH levels relative to ICL (2008) with a further proportionate reduction after four years of sample storage (2012). Yet, both the assays displayed similar patterns of the time-course of urine LH measurement both before and after four years of frozen storage. In conclusion, we found that both immunoassays are suitable for urinary LH measurements with ICL assay being more robust for quantitative urinary LH measurement such as for anti-doping purposes, whereas the IF could be applicable for research studies where urine LH levels are compared within-study but not in absolute terms. Copyright © 2013 John Wiley & Sons, Ltd.

  20. Determination by flow cytometry polyploidy inducing-capacity of colchicine in Cajanus cajan (L.) Mill sp.

    PubMed

    Udensi, O U; Ontui, V

    2013-07-01

    The need to optimize flow cytometric analysis for the determination of ploidy level is a worthwhile venture to precisely know at what concentration of a mutagen and at what time of exposure polyploidy could be induced. Flow cytometry was used to determine the polyploidy inducing-capacity of colchicine in pigeon pea (Cajanus cajan (L.) Mill sp). Seeds of pigeon pea were soaked in three different concentrations of colchicine-5 mg, 10 and 15 mg L(-1) for 24, 48 and 72 h, respectively, while the control group was soaked in water. Treated seeds and those from the control were planted in a greenhouse using a Completely Randomized Design (CRD). Results show that colchicine induced tetraploids (4n) and mixoploids (2n+ 4n) as the concentration of colchicine increased and soaking duration. Days to seedling emergence increased as concentration of colchicine and duration of soaking increased while germination rate decreased proportionately with the increase in colchicine concentration and soaking duration but did not significantly affect percentage seedling survival. Explicitly, colchicine has the capacity of inducing polyploidy; especially tetraploids on the seeds of pigeon pea, which obviously could be harnessed for further breeding and improvement of the pigeon pea.

  1. 26 CFR 1.1361-1 - S corporation defined.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...) For taxable years beginning on or after January 1, 1997, a financial institution that uses the reserve... 1, 1997, a financial institution to which section 585 applies (or would apply but for section 585(c... shareholder with respect to the owner's proportionate share of the stock held by the trust. (F) If S...

  2. THE STRENGTH OF A SPARROW.

    ERIC Educational Resources Information Center

    HOWE, HAROLD, II

    UNEQUAL DISTRIBUTION IN SOME STATES OF STATE TAX MONIES FOR SCHOOLS HAS RESULTED IN A MUCH HIGHER PROPORTIONATE FUNDING FOR SUBURBAN SCHOOLS THAN URBAN SCHOOLS. THIS FISCAL INEQUITY IS DUE TO EXCESSIVE RELIANCE UPON THE NUMBER OF DOLLARS OF ASSESSED VALUE BEHIND EACH STUDENT IN THE DISTRICT AND TO FAILURE BY THE STATES TO RECOGNIZE THE…

  3. Public Expenditures on Children through 2008: Key Facts

    ERIC Educational Resources Information Center

    Macomber, Jennifer; Isaacs, Julia; Kent, Adam; Vericker, Tracy

    2010-01-01

    This report provides the key findings on the public spending on children through 2008. They are: (1) Spending on children increased under the American Recovery and Reinvestment Act (ARRA) and other stimulus spending, but not proportionately to other federal spending. As ARRA expires, we project that spending on children will decline, assuming no…

  4. 75 FR 18488 - Intent To Grant an Exclusive License of U.S. Government-Owned Patent

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-12

    ... ``System and Method for the Deconvolution of Mixed DNA Profiles Using a Proportionately Shared Allele Approach'' to Niche Vision Forensics, LLC, with its principal place of business at 526 South Main Street Suite 714 G, Akron, OH 44311. ADDRESSES: Commander, U.S. Army Medical Research and Materiel Command...

  5. Education: Chemistry Faculties Gain Women Slowly.

    ERIC Educational Resources Information Center

    Chemical and Engineering News, 1984

    1984-01-01

    Highlights survey results on the status of females in full-time, tenured or tenure track faculty positions in chemistry. Indicates that males still dominate PhD-granting chemistry faculties and that, although the number of women is increasing, the increase is not proportionate to the rate at which they are earning chemistry PhDs. (JM)

  6. Prenatal Care and Pregnancy Outcomes during the Recession: The Washington State Experience.

    ERIC Educational Resources Information Center

    Fisher, Elliott S.; And Others

    1985-01-01

    During a period of increasing unemployment and decreased Medicaid eligibility, more women residents of low-income census tracts in Washington State received delayed prenatal care or none at all and delivered proportionately more infants of low birthweight. The incidence of maternal anemia also may have increased. (Author/GC)

  7. Proportionate Responses to Life Events Influence Clinicians' Judgments of Psychological Abnormality

    ERIC Educational Resources Information Center

    Kim, Nancy S.; Paulus, Daniel J.; Gonzalez, Jeffrey S.; Khalife, Danielle

    2012-01-01

    Psychological abnormality is a fundamental concept in the "Diagnostic and Statistical Manual of Mental Disorders" ("DSM-IV-TR"; American Psychiatric Association, 2000) and in all clinical evaluations. How do practicing clinical psychologists use the context of life events to judge the abnormality of a person's current behaviors? The appropriate…

  8. The Globalization of Education: Facing New Realities.

    ERIC Educational Resources Information Center

    Cappon, Paul

    2002-01-01

    In World Trade Organization negotiations, it has been proposed that education be treated as a service to be exchanged for profit. This is contrary to the United Nations covenant that education is a universal human right. Educators need to affirm that knowledge is not a commodity, but something whose benefit increases proportionately with the…

  9. The Economics of Pollution. Economic Topic Series.

    ERIC Educational Resources Information Center

    Wolozin, Harold

    One of the major reasons for the present concern for the pollution of the environment lies in the doubts about whether economic growth is possible without proportionate increases in the pollution of our air, land, and water. In response, Professor Wolozin devotes Part One of this trilogy to examining the economic relationships that help to explain…

  10. easyCBM Norms. 2014 Edition. Technical Report #1409

    ERIC Educational Resources Information Center

    Saven, Jessica L.; Tindal, Gerald; Irvin, P. Shawn; Farley, Dan; Alonzo, Julie

    2014-01-01

    Previous norms for the easyCBM assessment system were computed using scores from all students who took each measure for every grade and benchmark season (fall, winter, and spring). During the 2013-­14 school year, new national norms were developed to more accurately (proportionately) represent reading and mathematics performance by two variables:…

  11. 27 CFR 53.174 - Determination of price readjustments.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... prompt payment, quantity buying over a specified period, the vendee's inventory of an article when new... article on which the tax was based is readjusted, that part of the tax which is proportionate to the part... readjustment of price to the purchaser may occur by reason of: (A) The return of the article, (B) The...

  12. Social and Economic Change in Rural Iowa: The Development of Rural Ghettos.

    ERIC Educational Resources Information Center

    Jacobsen, G. Michael; Albertson, Bonnie Sanderson

    1987-01-01

    Rural ghettos are created when proportionately large numbers of unemployed, low income, and elderly residents live in communities located 30 miles or more from communities which can provide the range of goods and services necessary for a decent quality of life. This definition may apply to 300 Iowa towns. (JHZ)

  13. Personality Type and Temperament in Industrial Education Students: A Descriptive Study.

    ERIC Educational Resources Information Center

    Edmunds, Neil; Schultz, Andrew

    1989-01-01

    Using Myers-Briggs Type Inventory, authors studied 213 industrial education students in 22 secondary schools in Nebraska to ascertain whether the inventory placed students proportionately into same categories as Myers-Briggs normative group--defined by Keirsey. Large numbers of Sensory Thinker (ST) type found in 60 percent of classes. STs aimed…

  14. 7 CFR 51.2849 - Damage.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... medium green color on one-third of the surface; (h) Sprouts when visible, or when concealed within the... proportionately shorter on smaller onions; (i) Peeling when more than one-half of the thin papery skin is missing... affected by an off-color, watersoaked condition. The off-color must be of some shade of brown or yellow; (l...

  15. 7 CFR 51.2849 - Damage.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... medium green color on one-third of the surface; (h) Sprouts when visible, or when concealed within the... proportionately shorter on smaller onions; (i) Peeling when more than one-half of the thin papery skin is missing... affected by an off-color, watersoaked condition. The off-color must be of some shade of brown or yellow; (l...

  16. M-Learning Challenges in Teaching Crosscutting Themes in the Education of Young People and Adults

    ERIC Educational Resources Information Center

    Ota, Marcos Andrei; de Araujo, Carlos Fernando, Jr.

    2016-01-01

    The challenges faced in using new technologies in the classroom are numerous, but contributions generated with their resolution can proportionately provide original and efficient teaching practices more in tune to students' eager learning needs. This article presents some strategies developed to help teachers in transversal themes classes using…

  17. "Boys Business": An Unusual Northern Australian Music Program for Boys in the Middle Years of Schooling

    ERIC Educational Resources Information Center

    Smith, Bob

    2004-01-01

    The Northern Territory's population commingles Anglo, European and Asian cultural communities. At over 25 percent, it also has Australia's proportionately largest indigenous population. Consequently it presents an amazing proving ground for people-related research projects. One such project is "Boys Business", involving middle years'…

  18. Identification of coniferous woods

    Treesearch

    B. Francis Kukachka

    1960-01-01

    The identification of coniferous woods is generally regarded as being more difficult than for the hardwood species. This is due to the fact that conifers are more elemental in their structure and, as a consequence, the number of diagnostic features that may he employed is proportionately smaller. Instructions are given here in the sequential use of primary diagnostic...

  19. Louisiana Annual Rural Manpower Report, MA 5-79, 1976.

    ERIC Educational Resources Information Center

    Louisiana State Dept. of Employment Security, Baton Rouge

    Stressing the provision of services to migrants and seasonal farmworkers in keeping with the U.S. District Court Order requiring and quantitatively proportionate service to this labor segment, the Rural Manpower Service provided a comprehensive program of service to all rural elements in Louisiana. Working in close conjunction with the Service was…

  20. 40 CFR 35.3560 - General payment and cash draw rules.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... ASSISTANCE STATE AND LOCAL ASSISTANCE Drinking Water State Revolving Funds § 35.3560 General payment and cash... for set-asides. A State may draw cash through the ACH for the full amount of costs incurred for set... proportionate Federal share of eligible incurred project costs. A State need not have disbursed funds for...

  1. 40 CFR 35.3560 - General payment and cash draw rules.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... ASSISTANCE STATE AND LOCAL ASSISTANCE Drinking Water State Revolving Funds § 35.3560 General payment and cash... for set-asides. A State may draw cash through the ACH for the full amount of costs incurred for set... proportionate Federal share of eligible incurred project costs. A State need not have disbursed funds for...

  2. 40 CFR 35.3560 - General payment and cash draw rules.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... ASSISTANCE STATE AND LOCAL ASSISTANCE Drinking Water State Revolving Funds § 35.3560 General payment and cash... for set-asides. A State may draw cash through the ACH for the full amount of costs incurred for set... proportionate Federal share of eligible incurred project costs. A State need not have disbursed funds for...

  3. Which Children Will Go to Secondary School? Factors Affecting Parents' Decisions in Rural Thailand.

    ERIC Educational Resources Information Center

    Williams, Lindy; And Others

    1997-01-01

    Interviews in 1,776 households in rural Thailand and parent focus groups revealed that larger families sent proportionately fewer children to secondary school. Parents sent more sons than daughters and more youngest than eldest children. Economic factors included children's perceived earnings potential, opportunity costs, and family poverty;…

  4. Recent Shifts on Aid by Elite Colleges Signal New Push To Help the Middle Class.

    ERIC Educational Resources Information Center

    Gose, Ben

    1998-01-01

    Several elite private colleges have announced additional financial aid sources for middle class students, because enrollment patterns suggested previous policies attracted proportionately more low- and high-income than middle-income students. One college feels the new policy encourages families to save for college. Critics say the institutions are…

  5. An Introduction to Biometrics Technology: Its Place in Technology Education

    ERIC Educational Resources Information Center

    Elliott, Stephen J.; Peters, Jerry L.; Rishel, Teresa J.

    2004-01-01

    The increased utilization of biometrics technology in the past few years has contributed to a strong growth pattern as the technology is used in a variety of facilities, including schools. Due to media exposure, students' familiarity with technology will continue to increase proportionately, which will result in an increased curiosity about…

  6. Serotonin release varies with brain tryptophan levels

    NASA Technical Reports Server (NTRS)

    Schaechter, Judith D.; Wurtman, Richard J.

    1990-01-01

    This study examines directly the effects on serotonin release of varying brain tryptophan levels within the physiologic range. It also addresses possible interactions between tryptophan availability and the frequency of membrane depolarization in controlling serotonin release. We demonstrate that reducing tryptophan levels in rat hypothalamic slices (by superfusing them with medium supplemented with 100 microM leucine) decreases tissue serotonin levels as well as both the spontaneous and the electrically-evoked serotonin release. Conversely, elevating tissue tryptophan levels (by superfusing slices with medium supplemented with 2 microM tryptophan) increases both the tissue serotonin levels and the serotonin release. Serotonin release was found to be affected independently by the tryptophan availability and the frequency of electrical field-stimulation (1-5 Hz), since increasing both variables produced nearly additive increases in release. These observations demonstrate for the first time that both precursor-dependent elevations and reductions in brain serotonin levels produce proportionate changes in serotonin release, and that the magnitude of the tryptophan effect is unrelated to neuronal firing frequency. The data support the hypothesis that serotonin release is proportionate to intracellular serotonin levels.

  7. Fewer but better: Proportionate size of the group affects evaluation of transgressive leaders.

    PubMed

    Travaglino, Giovanni A; Abrams, Dominic; Randsley de Moura, Georgina; Yetkili, Orkun

    2016-06-01

    A group may be badly affected if its leader transgresses important rules. Nonetheless, an emerging body of evidence suggests that in intergroup contexts, group members apply a double standard when judging ingroup leaders - They respond less punitively to transgressions by their leader than by non-leaders. In this article, two experiments investigated how proportionate ingroup size affects reactions to transgressive ingroup leaders. We demonstrate that ingroup leaders from larger, but not smaller, groups benefit from the double standard. The experiments testing the effects of two different types of transgressions (nepotistic favouritism and corruption, respectively) show that transgressive leaders from larger groups are evaluated more positively than both comparable non-leaders and leaders from smaller groups. In contrast, transgressive leaders from smaller groups are evaluated similarly to comparable transgressive non-leaders. Experiment 2 investigated a potential explanation for this phenomenon. Faced with a transgressive leader, members of a smaller group report greater embarrassment than do members of larger groups in relation to the leaders' actions. Implications of these findings and directions for future research are discussed. © 2015 The British Psychological Society.

  8. 12q14 microdeletion associated with HMGA2 gene disruption and growth restriction.

    PubMed

    Alyaqoub, Fadel; Pyatt, Robert E; Bailes, Andrea; Brock, Amanda; Deeg, Carol; McKinney, Aimee; Astbury, Caroline; Reshmi, Shalini; Shane, Kate P; Thrush, Devon Lamb; Sommer, Annemarie; Gastier-Foster, Julie M

    2012-11-01

    The 12q14 microdeletion syndrome is a rare condition that has previously been characterized by pre- and postnatal growth restriction, proportionate short stature, failure to thrive, developmental delay, and osteopoikilosis. Previously reported microdeletions within this region have ranged in size from 1.83 to 10.12 Mb with a proposed 2.61 Mb smallest region of overlap containing the LEMD3, HMGA2, and GRIP1 genes. Here, we report on the identification of a 12q14 microdeletion in a female child presenting with proportionate short stature, failure to thrive, and speech delay. The genomic loss (minimum size 4.17 Mb, maximum size 4.21 Mb) contained 25 RefSeq genes including IRAK3, GRIP1, and the 3' portion of the HMGA2 gene. This is the first partial deletion of HMGA2 associated with the 12q14 microdeletion syndrome. This case further clarifies the association of LEMD3 deletions with the 12q14 microdeletion syndrome and provides additional support for the role of the HMGA2 gene in human growth. Copyright © 2012 Wiley Periodicals, Inc.

  9. Palliative sedation for intolerable suffering.

    PubMed

    Maltoni, Marco; Scarpi, Emanuela; Nanni, Oriana

    2014-07-01

    The purpose of this review is to provide an update on palliative sedation in palliative and end-of-life care. Palliative sedation is the medical procedure used to deal with refractory symptoms in advanced cancer patients when all other specific approaches have failed. Palliative sedation, in the strictest sense of the term, is a proportionate (proportionate palliative sedation, PPS) and intrinsically variable procedure used on an individual basis to relieve refractory symptoms in terminally ill patients, without the intention of hastening death. Completely separate from any other end-of-life decision and not intended to hasten death, palliative sedation has been shown not to have a detrimental impact on survival. To maintain palliative sedation as a legitimate clinical procedure from any ethical or clinical point of view, it must be limited to the restricted area for which it was conceived, that is, relief from refractory suffering as deemed necessary by a patient and by an experienced palliative care team. In this way, there is no risk of associating palliative sedation with other end-of-life decisions. Close collaboration is needed between oncologists and palliative care physicians for this clinical procedure.

  10. Iodine deficiency in children: A comparative study in two districts of south-interior Karnataka, India.

    PubMed

    Ahmed, Mansoor; Zama, Syed Y; Nagarajarao, Vadiraja; Khan, Mudassir A

    2014-01-01

    Iodine is an essential component of the hormones produced by the thyroid gland that are essential for mammalian life. Although goiter is the most visible sequelae of iodine deficiency, the major impact of hypothyroidism as a result of iodine deficiency is impaired neurodevelopment, particularly early in life. According to the World Health Organization, it is the single most preventable cause of mental retardation and brain damage. The simplest, most effective and inexpensive preventive method is the consumption of iodized salt. The objective of the following study is to estimate the prevalence of goiter in children in the rural areas of Mysore and Coorg districts in India and estimate iodine levels in salt samples. A cross-sectional study in the age group of 6-12 years, using population proportionate to size systematic sampling method. The total sample size was 10,082: out of which 5337 was from Mysore and the rest from Coorg district. Clinical examination of the thyroid gland was done and salt samples collected for the estimation of Iodine. The total prevalence of goiter was 19.01% in children of 6-12 years in Coorg district and 8.77% in Mysore district and it was more in females than in males. It was observed that iodine deficiency disorders is endemic in both districts, with a prevalence of 19.01% in children aged 6-12 years in Coorg district and 8.77% in Mysore district. Analysis of salt samples suggested that most of the samples were inadequately iodised (73.92% in Coorg and 45.92% in Mysore).

  11. Smoking Prevention for Students: Findings From a Three-Year Program of Integrated Harm Minimization School Drug Education.

    PubMed

    Midford, Richard; Cahill, Helen; Lester, Leanne; Foxcroft, David R; Ramsden, Robyn; Venning, Lynne

    2016-01-01

    This study investigated the impact of the Drug Education in Victorian Schools (DEVS) program on tobacco smoking. The program taught about licit and illicit drugs in an integrated manner over 2 years, with follow up in the third year. It focused on minimizing harm, rather than achieving abstinence, and employed participatory, critical-thinking and skill-based teaching methods. A cluster-randomized, controlled trial of the program was conducted with a student cohort during years 8 (13 years), 9 (14 years), and 10 (15 years). Twenty-one schools were randomly allocated to the DEVS program (14 schools, n = 1163), or their usual drug education program (7 schools, n = 589). One intervention school withdrew in year two. There was a greater increase in the intervention students' knowledge about drugs, including tobacco, in all 3 years. Intervention students talked more with their parents about smoking at the end of the 3-year program. They recalled receiving more education on smoking in all 3 years. Their consumption of cigarettes had not increased to the same extent as controls at the end of the program. Their change in smoking harms, relative to controls, was positive in all 3 years. There was no difference between groups in the proportionate increase of smokers, or in attitudes towards smoking, at any time. These findings indicate that a school program that teaches about all drugs in an integrated fashion, and focuses on minimizing harm, does not increase initiation into smoking, while providing strategies for reducing consumption and harm to those who choose to smoke.

  12. Aneuploidy and asynchronous replication in non-alcholic fatty liver disease and cryptogenic cirrhosis.

    PubMed

    Laish, Ido; Mannasse-Green, Batya; Hadary, Ruth; Konikoff, Fred M; Amiel, Aliza; Kitay-Cohen, Yona

    2016-11-15

    Non-alcoholic fatty liver disease (NAFLD) and cryptogenic cirrhosis (CC), which is largely a late sequela of NAFLD, are considered pre-neoplastic conditions that might progress to hepatocellular carcinoma. Aneuploidy, telomere aggregates and synchronization of replication were evaluated as markers of genetic instability in these patients. Peripheral blood lymphocytes from 22 patients with NAFLD, 20 patients with CC and 20 age-matched healthy controls were analyzed. To determine random aneuploidy, we used the fluorescence in situ hybridization (FISH) with probes for chromosomes 9 and 18. The rate of aneuploidy was inferred from the fraction of cells revealing one, three or more hybridization signals per cell. Aggregate size was divided into three fusion groups of 2-5, 6-10 and 11-15 telomeres, relative to the size of a single telomere. The replication pattern was determined by FISH in two pairs of alleles, 15qter and 13qter. Asynchrony was determined by the presence of one single and one set of double dots in the same cell. Significantly higher random aneuploidy rate was found in the CC patients than in the control group, and to a lesser degree in NAFLD patients. Telomere aggregates were insignificantly higher in both groups. Only patients with CC showed significantly higher rate of asynchronous replication with proportionately more cells with two single dots among the normal cells (p<0.001). These results likely reflect changes in gene replication and cell cycle progression in these conditions, possibly correlating with their malignant potential. Copyright © 2016 Elsevier B.V. All rights reserved.

  13. Evidence for Neuroplastic Compensation in the Cerebral Cortex of Persons with Depressive Illness

    PubMed Central

    Bansal, Ravi; Hellerstein, David J.; Peterson, Bradley S.

    2017-01-01

    We yoked anatomical brain Magnetic Resonance Imaging to a randomized, double-blind, placebo-controlled trial (RCT) of antidepressant medication for 10-week’s duration in patients with dysthymia. The RCT study design mitigated ascertainment bias by randomizing patients to receive either duloxetine or placebo, and it supported true causal inferences about treatment effects on the brain by controlling treatment assignment experimentally. We acquired 121 anatomical scans: at baseline and endpoint in 41 patients, and once in 39 healthy controls. At baseline, patients had diffusely thicker cortices than did healthy participants, and patients who had thicker cortices had proportionately less severe symptoms. During the trial, symptoms improved significantly more in medication- compared with placebo-treated patients; concurrently, thicknesses in medication-treated patients declined toward values in healthy controls, but they increased slightly, away from control values, in placebo-treated patients. Changes in symptom severity during the trial mediated the association of treatment assignment with the change in thickness, suggesting that the beneficial effects of medication on symptom severity were at least partially responsible for normalizing cortical thickness. Together our findings suggest that baseline cortical hypertrophy in medication-free patients likely represented a compensatory, neuroplastic response that attenuated symptom severity. Medication then reduced symptoms and lessened the need for compensation, thereby normalizing thickness. This is to the best of our knowledge the first study to report within an RCT a differential change in cortical morphology during medication treatment for depressive illness and the first to provide within an RCT in vivo evidence for the presence of neuroanatomical plasticity in humans. PMID:28265119

  14. Rapid assessment of avoidable blindness in Bhutan.

    PubMed

    Lepcha, Nor Tshering; Chettri, Chandra Kumar; Getshen, Kunzang; Rai, Bhim Bahadur; Ramaswamy, Shamanna Bindiganavale; Saibaba, Saravanan; Nirmalan, Praveen Kumar; Demarchis, Emilia Hansson; Tabin, Geoffrey; Morley, Michael; Morley, Katharine

    2013-08-01

    To conduct a rapid assessment of avoidable blindness survey in Bhutan to obtain estimates of blindness, visual impairment, and cataract surgical coverage, outcomes and barriers among persons ≥50 years old. A total of 82 clusters of 50 people ≥50 years were selected using probability proportionate to size sampling. Eligible participants were selected from households using compact segment sampling, and underwent ophthalmic examination for visual acuity, followed by penlight and direct ophthalmoscopy. Participants with cataract were interviewed regarding surgical outcomes and barriers to surgery. Overall, 4046 of 4100 persons enumerated (98.7%) underwent ophthalmic examination. Adjusting for age and sex, the prevalence of bilaterally blind persons with available correction was 1.5% (95% confidence interval 1.09-1.89). Most blindness (67.1%) and severe visual impairment (74.1%) resulted from cataract, but 22.1% resulted from posterior segment pathology. Cataract surgical coverage for bilaterally blind persons was 72.7%. Almost 90% of patients reported moderate or good satisfaction, despite poor surgical outcomes in 23.6%. The prevalence of blindness in people aged ≥50 years in Bhutan was relatively low when compared with neighboring countries and World Health Organization sub-region estimates. Areas for improvement include community outreach, surgical outcomes, and posterior segment diseases.

  15. Estimation of Mineral and Trace Element Profile in Bubaline Milk Affected with Subclinical Mastitis.

    PubMed

    Singh, Mahavir; Yadav, Poonam; Sharma, Anshu; Garg, V K; Mittal, Dinesh

    2017-04-01

    The milk samples from buffaloes of Murrah breed at mid lactation stage, reared at an organised dairy farm, were screened for subclinical mastitis based on bacteriological examination and somatic cell count following International Dairy Federation criteria. Milk samples from subclinical mastitis infected and healthy buffaloes were analysed to evaluate physicochemical alterations in terms of protein, fat, pH, electrical conductivity, chloride, minerals (sodium, potassium and calcium) and trace elements (iron, zinc, copper and selenium). In the present study, protein, fat, zinc, iron, calcium and selenium content was significantly lower (P < 0.001), while pH and electrical conductivity were significantly higher in mastitic milk as compared to normal milk. Concentration of electrolytes mainly sodium and chloride significantly increased with higher somatic cell count in mastitic milk and to maintain osmolality; potassium levels decreased proportionately. Correlation matrix revealed significantly positive interdependences of somatic cell count with pH, electrical conductivity, sodium and chloride. However, protein, fat, calcium and potassium were correlated negatively with elevated somatic cell count in mastitic milk. It is concluded that udder infections resulting in elevated somatic cells may alter the mineral and trace element profile of milk, and magnitude of changes may have diagnostic and prognostic value.

  16. Constrained minimization problems for the reproduction number in meta-population models.

    PubMed

    Poghotanyan, Gayane; Feng, Zhilan; Glasser, John W; Hill, Andrew N

    2018-02-14

    The basic reproduction number ([Formula: see text]) can be considerably higher in an SIR model with heterogeneous mixing compared to that from a corresponding model with homogeneous mixing. For example, in the case of measles, mumps and rubella in San Diego, CA, Glasser et al. (Lancet Infect Dis 16(5):599-605, 2016. https://doi.org/10.1016/S1473-3099(16)00004-9 ), reported an increase of 70% in [Formula: see text] when heterogeneity was accounted for. Meta-population models with simple heterogeneous mixing functions, e.g., proportionate mixing, have been employed to identify optimal vaccination strategies using an approach based on the gradient of the effective reproduction number ([Formula: see text]), which consists of partial derivatives of [Formula: see text] with respect to the proportions immune [Formula: see text] in sub-groups i (Feng et al. in J Theor Biol 386:177-187, 2015.  https://doi.org/10.1016/j.jtbi.2015.09.006 ; Math Biosci 287:93-104, 2017.  https://doi.org/10.1016/j.mbs.2016.09.013 ). These papers consider cases in which an optimal vaccination strategy exists. However, in general, the optimal solution identified using the gradient may not be feasible for some parameter values (i.e., vaccination coverages outside the unit interval). In this paper, we derive the analytic conditions under which the optimal solution is feasible. Explicit expressions for the optimal solutions in the case of [Formula: see text] sub-populations are obtained, and the bounds for optimal solutions are derived for [Formula: see text] sub-populations. This is done for general mixing functions and examples of proportionate and preferential mixing are presented. Of special significance is the result that for general mixing schemes, both [Formula: see text] and [Formula: see text] are bounded below and above by their corresponding expressions when mixing is proportionate and isolated, respectively.

  17. Women otolaryngologist representation in specialty society membership and leadership positions.

    PubMed

    Choi, Sukgi S; Miller, Robert H

    2012-11-01

    To determine the proportion of female otolaryngologists in leadership positions relative to their number in the specialty, their membership in various otolaryngology organizations, and age. Cross-sectional analyses of otolaryngology organization membership with a subgroup analysis on female membership and leadership proportion comparing 5-year male/female cohort groups. Information on the number of members and leaders was obtained from various specialty societies by direct communication and from their Web sites between June and December 2010. The number of female and male otolaryngologists and their age distribution in 5-year age groups was obtained from the American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS). Statistical analyses were used to determine whether women had proportional membership and leadership representation in various specialty societies. Additionally, female representation in other leadership roles was analyzed using the male/female ratio within the 5-year cohort groups. Female otolaryngologists were found to constitute approximately 11% of practicing otolaryngologists. The American Society of Pediatric Otolaryngology had a higher proportion of female members (22%) compared to five other societies. When the gender composition within each organization was taken into account, female representation in specialty society leadership positions was proportionate to their membership across all societies. When gender and age were considered, women have achieved proportionate representation in each of the specialty societies' leadership positions. There was also proportionate representation of females as program directors, American Board of Otolaryngology directors, Residency Review Committee members, and journal editors/editorial board members. Finally, fewer female chairs or chiefs of departments/divisions were seen, but when age was taken into consideration, this difference was no longer significant. Women have achieved parity in otolaryngology leadership positions. As the number and seniority of women increase, the specialty should continue to monitor representation of women in leadership positions. Copyright © 2012 The American Laryngological, Rhinological, and Otological Society, Inc.

  18. Proportional costs in trauma and acute care surgery patients: dominant role of intensive care unit costs.

    PubMed

    Fakhry, Samir M; Martin, Brad; Al Harakeh, Hasan; Norcross, E Douglas; Ferguson, Pamela L

    2013-04-01

    Controlling inpatient costs is increasingly important. Identifying proportionately larger cost categories may help focus cost control efforts. The purpose of this study was to identify proportionate patient cost categories in trauma and acute care surgery (TACS) patients and determine subgroups in which the largest opportunities for cost savings might exist. Administrative data from our academic, urban, level I trauma center were used to identify all adult TACS patients from FY07 through FY11. We determined, on average, what proportion of the whole each cost category contributed to patients' total costs and examined the same proportions for subgroups of patients. We identified 6,008 TACS patients. Trauma patients (n = 3,904) made up 65% of the cohort (mean Injury Severity Score 13.2). Payers were: 22% government (Medicare, Medicaid, Champus), 27% private, 43% self-pay/indigent, 3% other, and 5% workers compensation. Nontrauma (general surgery) patients (n = 2,104) made up 35% of the cohort. Payers were: 44% government, 24% private, 29% self-pay/indigent, 2% other, and 1% workers compensation. Total inpatient costs were $141,304,993. Per patient costs rose from $17,245 in FY07 to $26,468 in FY11. In the aggregate, supplies, ICU stays, and ward stays represented the largest proportionate cost categories. On a per patient basis, however, ICU stays were by far the largest cost. Patients with ICU stay greater than 10 days were only 7% of all patients but accounted for 41% of total costs. Trauma and acute care surgery patients represent a significant and increasing institutional cost. Per patient ICU costs were the largest single category, suggesting that cost control efforts should focus heavily on critically ill patients. Nontrauma patients who require critical care have the highest per patient ICU costs and may represent a previously underappreciated opportunity for cost control. Copyright © 2013 American College of Surgeons. Published by Elsevier Inc. All rights reserved.

  19. Nonuniform sampling theorems for random signals in the linear canonical transform domain

    NASA Astrophysics Data System (ADS)

    Shuiqing, Xu; Congmei, Jiang; Yi, Chai; Youqiang, Hu; Lei, Huang

    2018-06-01

    Nonuniform sampling can be encountered in various practical processes because of random events or poor timebase. The analysis and applications of the nonuniform sampling for deterministic signals related to the linear canonical transform (LCT) have been well considered and researched, but up to now no papers have been published regarding the various nonuniform sampling theorems for random signals related to the LCT. The aim of this article is to explore the nonuniform sampling and reconstruction of random signals associated with the LCT. First, some special nonuniform sampling models are briefly introduced. Second, based on these models, some reconstruction theorems for random signals from various nonuniform samples associated with the LCT have been derived. Finally, the simulation results are made to prove the accuracy of the sampling theorems. In addition, the latent real practices of the nonuniform sampling for random signals have been also discussed.

  20. 26 CFR 1.957-1 - Definition of controlled foreign corporation.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... proportionate share of the corporate earnings, if the facts indicate that the shareholders of such other class..., and if a principal purpose of the arrangement is to avoid the classification of such foreign... corporate directors, and the owners of a majority of the class B stock are entitled to elect the other 4 of...

  1. Dispute Resolution in Additional and Special Educational Needs: Local Authority Perspectives

    ERIC Educational Resources Information Center

    Riddell, Sheila; Harris, Neville; Smith, Emily; Weedon, Elisabet

    2010-01-01

    The UK Government is keen to encourage the use of mediation, rather than court or tribunal, as the best means of resolving disputes between citizen and state on the grounds that legal proceedings are costly, lengthy and stressful. The policy of proportionate dispute resolution appears to be particularly applicable to the field of special…

  2. Factors Contributing to Regular Smoking in Adolescents in Turkey

    ERIC Educational Resources Information Center

    Can, Gamze; Topbas, Murat; Oztuna, Funda; Ozgun, Sukru; Can, Emine; Yavuzyilmaz, Asuman

    2009-01-01

    Purpose: The objectives of this study were to determine the levels of lifetime cigarette use, daily use, and current use among young people (aged 15-19 years) and to examine the risk factors contributing to regular smoking. Methods: The number of students was determined proportionately to the numbers of students in all the high schools in the…

  3. A Five Year Analysis of Female vs. Male College Students' Persistence to Graduation: One Case Study.

    ERIC Educational Resources Information Center

    Stoner, Kenneth L.; DeRidder, Janet Waller

    1982-01-01

    Recent literature indicates sex is related to retention with more men persisting to graduation. In this University of Tennessee (Knoxville) study, analysis according to sex classification produced results contrary to the latest research findings: rather than males, females tended to graduate earlier or on schedule proportionately more frequently…

  4. 26 CFR 1.963-2 - Determination of the amount of the minimum distribution.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... taxable year between two or more classes of stock depends upon the exercise of discretion by that body of... such earnings and profits is made by such body not later than 90 days after the close of such taxable... proportion of such foreign income tax that such shareholder's proportionate share (as determined under...

  5. 26 CFR 1.963-2 - Determination of the amount of the minimum distribution.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... taxable year between two or more classes of stock depends upon the exercise of discretion by that body of... such earnings and profits is made by such body not later than 90 days after the close of such taxable... proportion of such foreign income tax that such shareholder's proportionate share (as determined under...

  6. 26 CFR 1.963-2 - Determination of the amount of the minimum distribution.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... taxable year between two or more classes of stock depends upon the exercise of discretion by that body of... such earnings and profits is made by such body not later than 90 days after the close of such taxable... proportion of such foreign income tax that such shareholder's proportionate share (as determined under...

  7. 26 CFR 1.963-2 - Determination of the amount of the minimum distribution.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... taxable year between two or more classes of stock depends upon the exercise of discretion by that body of... such earnings and profits is made by such body not later than 90 days after the close of such taxable... proportion of such foreign income tax that such shareholder's proportionate share (as determined under...

  8. 26 CFR 1.963-2 - Determination of the amount of the minimum distribution.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... taxable year between two or more classes of stock depends upon the exercise of discretion by that body of... such earnings and profits is made by such body not later than 90 days after the close of such taxable... proportion of such foreign income tax that such shareholder's proportionate share (as determined under...

  9. Atrophic alopecia in the Hallermann-Strieff syndrome.

    PubMed

    Grattan, C E; Liddle, B J; Willshaw, H E

    1989-05-01

    We report a case of the Hallermann-Strieff syndrome with focal scalp atrophy and associated patchy hair loss. Cases of the Hallermann-Strieff syndrome (a branchial arch syndrome) often present with ocular abnormalities in infancy but they also show a number of other abnormalities including a characteristic facial appearance, proportionate dwarfism, cutaneous atrophy, hypotrichosis and dental anomalies.

  10. Ethical Review of Undergraduate Student Research Projects: A Proportionate, Transparent and Efficient Process?

    ERIC Educational Resources Information Center

    Hack, Catherine J.

    2012-01-01

    Undergraduate research projects in the life sciences encompass a broad range of studies, some of which may require the participation of human subjects or other activities which may raise ethical concerns. As universities are accountable for all projects undertaken under their auspices they must ensure that these projects adhere to legal…

  11. Mothers' and Fathers' Questions to Their Child in Mexican-Descent Families: Moderators of Cognitive Demand during Play.

    ERIC Educational Resources Information Center

    Tenenbaum, Harriet R.; Leaper, Campbell

    1997-01-01

    The cognitive demand in questions directed to Mexican-descent children by their mothers and fathers were analyzed for videotaped play situations involving gender-neutral, masculine-, or feminine-stereotyped toys. Mothers asked proportionately more conceptual questions than did fathers. Mothers' question asking was influenced by child gender,…

  12. 17 CFR 256.255 - Accumulated deferred investment tax credits.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... overall income tax expense in the year in which a tax credit is realized. A proportionate amount shall be debited to account 411.5, Investment tax credit, as determined in relation to the average useful life of... investment tax credits for each year with the weighted-average service life of such properties and any unused...

  13. The Children (Northern Ireland) Order 1995 10 Years on: The Resource Demands of Legislative Change

    ERIC Educational Resources Information Center

    Donaldson, Theresa; Harbison, Jeremy

    2006-01-01

    In the paper "A Fairer Deal For Legal Aid" (2005), the Department of Constitutional Affairs poses the question: Are we ensuring that system resources are used in the "most proportionate, efficient, effective and timely way to ensure the best possible outcomes for children and families?" This paper argues that the issue of…

  14. Overwhelmed in Cincinnati: Urban Appalachian Children and Youth. Draft.

    ERIC Educational Resources Information Center

    Borman, Kathryn M.

    The issues facing urban Appalachian children and their families in Cincinnati (Ohio) are addressed. Appalachians have the highest school dropout rate in Cincinnati proportionate to their numbers, with low access to jobs and generally poor access to, and use of, public services. Much of the information for this report comes from a survey of 246…

  15. "La Influencia De La Familia": Latino Retention in Higher Education

    ERIC Educational Resources Information Center

    Fort Daniels, Tonya

    2012-01-01

    Although the Latino population is currently the largest minority ethnicity in the U.S. (U.S. Census, 2008), Latino students enroll in college and graduate in proportionately the smallest numbers (Latino, 2002). This dissertation examined the effect of Latino students' families on their decision to remain in school and finish a bachelor's…

  16. Tensions between Policy and Workplace Opportunities in Rural Arizona: Does Public Policy Ignore Social Equality?

    ERIC Educational Resources Information Center

    Danzig, Arnold; Vandegrift, Judith A.

    Resources available to Arizona through the School-to-Work Opportunities Act will not be concentrated in rural communities, although their educational and economic development needs are proportionately greater. Absent from education reform bills pending in the Arizona House and Senate is any reference to school-to-work transition or any explicit…

  17. The Influence of Contextual Change on Remembering in Short-Term Memory. Final Report.

    ERIC Educational Resources Information Center

    Falkenberg, Philippe R.

    If the contextual similarity between learning and recall within a single trial in a short-term memory (STM) paradigm is varied, recall varies proportionately. This context effect was demonstrated using variations of the Peterson-Peterson (1959) paradigm for both aurally and visually presented material, verbal and arithmetic context, and within and…

  18. Dendrimers and methods of preparing same through proportionate branching

    DOEpatents

    Yu, Yihua; Yue, Xuyi

    2015-09-15

    The present invention provides for monodispersed dendrimers having a core, branches and periphery ends, wherein the number of branches increases exponentially from the core to the periphery end and the length of the branches increases exponentially from the periphery end to the core, thereby providing for attachment of chemical species at the periphery ends without exhibiting steric hindrance.

  19. Not Black Like Me: The Cultural Journey of an Early Childhood Program

    ERIC Educational Resources Information Center

    Murray, Mary M.; Mereoiu, Marian; Cassidy, Deborah; Vardell, Rosemarie; Niemeyer, Judith A.; Hestenes, Linda

    2016-01-01

    Universities and colleges across the United States have been increasingly intentional in their effort to become educational institutions with a culture reflective of all their students, faculty and staff. However, achieving a proportionate representation of faculty for the community of students they serve seems to be a goal yet to be achieved by…

  20. Exclusionary Discipline Practices across Students' Racial/Ethnic Backgrounds and Disability Status: Findings from the Pacific Northwest

    ERIC Educational Resources Information Center

    Vincent, Claudia G.; Sprague, Jeffrey R.; Tobin, Tary J.

    2012-01-01

    We examined 2009-2010 data on exclusionary discipline practices from one state in the Pacific Northwest of the United States across students' racial/ethnic backgrounds and disability status. Our focus was on proportionate representation in exclusionary discipline actions and in the duration of those disciplinary actions. Descriptive outcomes…

  1. Dynamics of aspen root biomass and sucker production following fire

    Treesearch

    Roy A. Renkin; Don G. Despain

    2001-01-01

    Changes in preburn aspen root biomass 8 years following prescribed fire were analyzed for five experimental sites distributed across a moisture gradient. Total root biomass decreased across all sites but was proportionately greater in xeric than mesic sites. Response of post-burn aspen suckers to ungulate browsing varied according to site and treatment. Browsing...

  2. Improvement cuttings on farm woodlands bring good dividends

    Treesearch

    Carl J. Holcomb

    1954-01-01

    West Virginia farmers own one-third of the forest in the State - more than 3 million acres. If these woodland areas were given the same attention and care that is given to cropland, within a few years West Virginia farm forests could be producing their proportionate share of the farm income. Yet the farm woods are almost completely neglected.

  3. 42 CFR 57.307 - Maximum amount of nursing student loans.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Maximum amount of nursing student loans. 57.307... Nursing Student Loans § 57.307 Maximum amount of nursing student loans. The total of the nursing student... longer than the 9-month academic year may be proportionately increased. The total of all nursing student...

  4. 42 CFR 57.307 - Maximum amount of nursing student loans.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Maximum amount of nursing student loans. 57.307... Nursing Student Loans § 57.307 Maximum amount of nursing student loans. The total of the nursing student... longer than the 9-month academic year may be proportionately increased. The total of all nursing student...

  5. 42 CFR 57.307 - Maximum amount of nursing student loans.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 1 2013-10-01 2013-10-01 false Maximum amount of nursing student loans. 57.307... Nursing Student Loans § 57.307 Maximum amount of nursing student loans. The total of the nursing student... longer than the 9-month academic year may be proportionately increased. The total of all nursing student...

  6. 42 CFR 57.307 - Maximum amount of nursing student loans.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 1 2012-10-01 2012-10-01 false Maximum amount of nursing student loans. 57.307... Nursing Student Loans § 57.307 Maximum amount of nursing student loans. The total of the nursing student... longer than the 9-month academic year may be proportionately increased. The total of all nursing student...

  7. 42 CFR 57.307 - Maximum amount of nursing student loans.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 1 2014-10-01 2014-10-01 false Maximum amount of nursing student loans. 57.307... Nursing Student Loans § 57.307 Maximum amount of nursing student loans. The total of the nursing student... longer than the 9-month academic year may be proportionately increased. The total of all nursing student...

  8. An In-Depth Analysis of Exemplary Female Superintendents: A Qualitative Inquiry

    ERIC Educational Resources Information Center

    Kay, Patricia L.

    2012-01-01

    The number of women who serve as public school district superintendents is inversely proportionate to the number of women who work in public schools. Men continue to dominate the occupancy of this position. Barriers that women encounter in their career journey and obstacles faced by women who serve in the role of superintendent have been…

  9. 75 FR 41337 - Implementation of Section 224 of the Act; A National Broadband Plan for Our Future

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-15

    ...) post-make- ready attachment of lines. As a result, there have been ongoing disagreements regarding the... interest in rolling out properly permitted facilities is proportionately larger. Therefore, for the post..., the Commission proposes to require such utilities to post or otherwise share with attachers a list of...

  10. Building Online Social Networks to Engage Female Students in Information Systems

    ERIC Educational Resources Information Center

    Shah, Jaymeen R.; Lee, Hsun-Ming

    2015-01-01

    During the next decade, enrollment growth in Information Systems (IS) related majors is unlikely to meet the predicted demand for qualified IS graduates. Gender imbalance in the IS related program makes the situation worse as enrollment and retention of women in the IS major has been proportionately low compared to male. In recent years, majority…

  11. Contaminant Gradients in Trees: Directional Tree Coring Reveals Boundaries of Soil and Soil-Gas Contamination with Potential Applications in Vapor Intrusion Assessment.

    PubMed

    Wilson, Jordan L; Samaranayake, V A; Limmer, Matthew A; Schumacher, John G; Burken, Joel G

    2017-12-19

    Contaminated sites pose ecological and human-health risks through exposure to contaminated soil and groundwater. Whereas we can readily locate, monitor, and track contaminants in groundwater, it is harder to perform these tasks in the vadose zone. In this study, tree-core samples were collected at a Superfund site to determine if the sample-collection location around a particular tree could reveal the subsurface location, or direction, of soil and soil-gas contaminant plumes. Contaminant-centroid vectors were calculated from tree-core data to reveal contaminant distributions in directional tree samples at a higher resolution, and vectors were correlated with soil-gas characterization collected using conventional methods. Results clearly demonstrated that directional tree coring around tree trunks can indicate gradients in soil and soil-gas contaminant plumes, and the strength of the correlations were directly proportionate to the magnitude of tree-core concentration gradients (spearman's coefficient of -0.61 and -0.55 in soil and tree-core gradients, respectively). Linear regression indicates agreement between the concentration-centroid vectors is significantly affected by in planta and soil concentration gradients and when concentration centroids in soil are closer to trees. Given the existing link between soil-gas and vapor intrusion, this study also indicates that directional tree coring might be applicable in vapor intrusion assessment.

  12. Contaminant gradients in trees: Directional tree coring reveals boundaries of soil and soil-gas contamination with potential applications in vapor intrusion assessment

    USGS Publications Warehouse

    Wilson, Jordan L.; Samaranayake, V.A.; Limmer, Matthew A.; Schumacher, John G.; Burken, Joel G.

    2017-01-01

    Contaminated sites pose ecological and human-health risks through exposure to contaminated soil and groundwater. Whereas we can readily locate, monitor, and track contaminants in groundwater, it is harder to perform these tasks in the vadose zone. In this study, tree-core samples were collected at a Superfund site to determine if the sample-collection location around a particular tree could reveal the subsurface location, or direction, of soil and soil-gas contaminant plumes. Contaminant-centroid vectors were calculated from tree-core data to reveal contaminant distributions in directional tree samples at a higher resolution, and vectors were correlated with soil-gas characterization collected using conventional methods. Results clearly demonstrated that directional tree coring around tree trunks can indicate gradients in soil and soil-gas contaminant plumes, and the strength of the correlations were directly proportionate to the magnitude of tree-core concentration gradients (spearman’s coefficient of -0.61 and -0.55 in soil and tree-core gradients, respectively). Linear regression indicates agreement between the concentration-centroid vectors is significantly affected by in-planta and soil concentration gradients and when concentration centroids in soil are closer to trees. Given the existing link between soil-gas and vapor intrusion, this study also indicates that directional tree coring might be applicable in vapor intrusion assessment.

  13. Quality of ground water in the Payette River basin, Idaho

    USGS Publications Warehouse

    Parliman, D.J.

    1986-01-01

    As part of a study to obtain groundwater quality data in areas of Idaho were land- and water-resource development is expected to increase, water quality, geologic, and hydrologic data were collected for 74 wells in the Payette River basin, west-central Idaho, from July to October 1982. Historical (pre-1982) data from 13 wells were compiled with more recent (1982) data to define, on a reconnaissance level, water quality conditions in major aquifers and to identify factors that may have affected groundwater quality. Water from the major aquifers generally contains predominantly calcium, magnesium, and bicarbonate plus carbonate ions. Sodium and bicarbonate or sulfate are the predominant ions in groundwater from 25% of the 1982 samples. Areally, groundwater from the upper Payette River basin has proportionately lower ion concentrations than water from the lower Payette River basin. Water samples from wells < 100 ft deep generally have lower ion concentrations than samples from wells > 100 ft deep. Variations in groundwater quality probably are most affected by differences in aquifer composition and proximity to source(s) of recharge. Groundwater in the study area is generally suitable for most uses. In localized areas, pH and concentrations of hardness, alkalinity, dissolved solids, or dissolved nitrite plus nitrate as nitrogen, sulfate, fluoride, iron, or manganese exceed Federal drinking water limits and may restrict some uses of the water.

  14. The prevalence, incidence, and gender and age-specific incidence of problem gambling: results of the Swedish longitudinal gambling study (Swelogs).

    PubMed

    Abbott, Max; Romild, Ulla; Volberg, Rachel

    2018-04-01

    To estimate the prevalence, incidence and gender and age-specific incidence of problem gambling in the Swedish adult population. Longitudinal cohort study with linkage to register data. Sweden. Stratified random sample aged 16-84 years at baseline (n = 8165) re-assessed a year later (n = 6021). Problem gambling (life-time and past 12 months) was measured by the South Oaks Gambling Screen-Revised (SOGS-R). Past 12-month (current) problem gambling was also measured by the Problem Gambling Severity Index (PGSI). The SOGS-R combined current pathological and problem gambling prevalence rate (PR) was 2.1 [95% confidence interval (CI) = 1.8-2.4] at baseline and 1.7 (1.4-2.0) at follow-up, approximately half the corresponding life-time estimates.[Correction added on 22 Dec 2017, after first online publication: In the preceding sentence, the SOGS-R combined current pathological and problem gambling prevalence rate (PR) was incorrectly reported as being double the corresponding life-time rate. It has been corrected in this version.] PGSI combined current problem and moderate-risk gambling PRs were 2.2 (1.9-2.5) at baseline and 1.9 (1.6-2.2) at follow-up. Combined incidence rates (IRs) were 1.0 (0.8-1.3) (SOGS-R) and 1.4 (1.1-1.7) (PGSI), with more than three-quarters being new cases. While first-time IRs did not vary by gender, males had a higher relapse IR and proportionately more females were new cases. The young adult IR was more than double the older adult IR; similar proportions were new cases. The actual incidence of problem gambling relapse in Sweden is likely to be higher than estimated. The profile of problem gambling in Sweden is likely to change over time, with increased proportions of women and older adults. © 2017 Society for the Study of Addiction.

  15. Cycloplegic autorefraction versus subjective refraction: the Tehran Eye Study.

    PubMed

    Hashemi, Hassan; Khabazkhoob, Mehdi; Asharlous, Amir; Soroush, Sara; Yekta, AbbasAli; Dadbin, Nooshin; Fotouhi, Akbar

    2016-08-01

    To compare cycloplegic autorefraction with non-cycloplegic subjective refraction across all age and refractive error groups. In a cross-sectional study with random stratified cluster sampling, 160 clusters were chosen from various districts proportionate to the population of each district in Tehran. Following retinoscopy and autorefraction with the 0.25 D bracketing (Topcon KR-8000, Topcon, Tokyo, Japan), all participants had a subjective refraction. Then all participants underwent cycloplegic autorefraction. The final analysis was performed on 3482 participants with a mean age of 31.7 years (range 5-92 years). Based on cycloplegic and subjective refraction, mean spherical equivalent (SE) was +0.31±1.80 and -0.32±1.61 D, respectively (p<0.001). The 95% limits of agreement (LoA) between these two types of refraction were from -0.40 to 1.70 D. The largest difference between these two types of refraction was seen in the age group of 5-10 years (1.11±0.60 D), and the smallest difference was in the age group of >70 years (0.34±0.45 D). The 95% LoA was -0.52 to 0.89 D in patients with myopia and -0.12 to 2.04 D in patients with hyperopia. We found that female gender (coefficients=0.048), older age (coefficients=-0.247), higher education (coefficients=-0.043) and cycloplegic SE (coefficients=-0.472) significantly correlated with lower intermethod differences. The cycloplegic refraction is more sensitive than the subjective one to measure refractive error at all age groups especially in children and young adults. The cyclorefraction technique is highly recommended to exactly measure the refractive error in momentous conditions such as refractive surgery, epidemiological researches and amblyopia therapy, especially in hypermetropic eyes and paediatric cases. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  16. Community pharmacy in Lebanon: A societal perspective.

    PubMed

    Iskandar, Katia; Hallit, Souheil; Raad, Etwal Bou; Droubi, Fida; Layoun, Nelly; Salameh, Pascale

    2017-01-01

    To assess patients' attitudes towards the community pharmacist's role and determine their negative and positive reactions towards community pharmacists in Lebanon. A cross-sectional study, conducted between January and April 2016, was designed to assess the general public satisfaction with the services provided by the community pharmacies. It was carried out, using a proportionate random sampling of Lebanese community pharmacies from each district. Two sided statistical tests were used to compare between group percentages, Wilcoxon test for quantitative variables with non-homogeneous variances or non-normal distribution, and Student's t-test for quantitative variables of normal distribution and homogeneous variances. The ANOVA test was used to compare between three groups or more, and Pearson correlation coefficient were used to correlate between quantitative variables. a total of 565 participants completely answered the survey questions with a response rate of 94%. The bivariate analysis showed that the patient perception index was positively and significantly correlated with the patient level of expectation index, the overall pharmacy experience and the patient's reason for visiting the pharmacy (p<0.001 for all 3 variables) but was negatively correlated with the barriers for asking questions significantly (p=0.032). On the other hand, this perception index was significantly and positively associated with the number of pharmacy visits, the age categories, the level of education and the family monthly income (p<0.05 for all variables). Public perception and attitude toward community pharmacist in Lebanon is poor despite highly qualified pharmacists. Aspects of pharmacy services most relevant to patients were respect, empathy, a friendly staff, listening carefully, giving quality time, responding quickly to their needs and respecting their privacy. The ministry of Health in Lebanon, along with the Lebanese Order of Pharmacists should educate the pharmacist about working on the different issues patients are complaining about in order to play a more important role in the society and become the number one trusted health care professional.

  17. Community pharmacy in Lebanon: A societal perspective

    PubMed Central

    Droubi, Fida

    2016-01-01

    Objective: To assess patients’ attitudes towards the community pharmacist’s role and determine their negative and positive reactions towards community pharmacists in Lebanon. Methods: A cross-sectional study, conducted between January and April 2016, was designed to assess the general public satisfaction with the services provided by the community pharmacies. It was carried out, using a proportionate random sampling of Lebanese community pharmacies from each district. Two sided statistical tests were used to compare between group percentages, Wilcoxon test for quantitative variables with non-homogeneous variances or non-normal distribution, and Student’s t-test for quantitative variables of normal distribution and homogeneous variances. The ANOVA test was used to compare between three groups or more, and Pearson correlation coefficient were used to correlate between quantitative variables. Results: a total of 565 participants completely answered the survey questions with a response rate of 94%. The bivariate analysis showed that the patient perception index was positively and significantly correlated with the patient level of expectation index, the overall pharmacy experience and the patient’s reason for visiting the pharmacy (p<0.001 for all 3 variables) but was negatively correlated with the barriers for asking questions significantly (p=0.032). On the other hand, this perception index was significantly and positively associated with the number of pharmacy visits, the age categories, the level of education and the family monthly income (p<0.05 for all variables). Conclusion: Public perception and attitude toward community pharmacist in Lebanon is poor despite highly qualified pharmacists. Aspects of pharmacy services most relevant to patients were respect, empathy, a friendly staff, listening carefully, giving quality time, responding quickly to their needs and respecting their privacy. The ministry of Health in Lebanon, along with the Lebanese Order of Pharmacists should educate the pharmacist about working on the different issues patients are complaining about in order to play a more important role in the society and become the number one trusted health care professional. PMID:28690690

  18. Access to water and sanitation facilities in primary schools: A neglected educational crisis in Ngamiland district in Botswana

    NASA Astrophysics Data System (ADS)

    Ngwenya, B. N.; Thakadu, O. T.; Phaladze, N. A.; Bolaane, B.

    2018-06-01

    In developing countries, the sanitation and hygiene provision often receives limited resources compared to the water supply. However, water supply benefits tend to diminish if improved sanitation and hygiene are neglected. This paper presents findings of a situational analysis of water supply, sanitation and hygiene infrastructure and their utilization in three primary schools in north-western Botswana. The overall objective of the paper is to determine access and functionality of water supply, sanitation and hygiene infrastructure in three primary schools. The specific objectives are: a) Learners' perspective of their water and sanitation facilities and b) gendered utilization of sanitation and hygiene facilities. Data were collected through a face-to-face administered social survey tool to 286 learners selected through proportionate stratified random sampling from three purposively selected villages in the middle and lower Okavango Delta. Findings indicate that standpipes provide 96% of potable water supply. However, the majority (65% of leaners) indicated that they 'sometimes' experienced water shortage due to dry/nonfunctioning taps/pumps and leaks/wastage. Overall, schools have relatively sufficient sanitation facilities consisting of both water borne toilets and VIP latrines. The major sanitation gap identified was that 80% flush toilets hardly work, while 77% of VIP toilets were in disrepair. Furthermore, poor water supply compromised hand washing with 65.7% learners "always" washing their hands if school standpipes had water, while the majority did not wash hands if standpipes were dry. The study concluded that availability of sanitation infrastructure does not necessarily translate into utilization in the study area due to multiple problems, such as lack of personal hygiene supplies (regular toilet paper and hand washing detergents), privacy issues and recurring water problems. The chronicity of inadequate water, sanitation and hygiene infrastructure in primary schools is critical and there is urgent need to address these challenges in order to create a conducive learning environment in primary schools in the district.

  19. Sexual homicides in South Africa: A national cross-sectional epidemiological study of adult women and children.

    PubMed

    Abrahams, Naeemah; Mathews, Shanaaz; Lombard, Carl; Martin, Lorna J; Jewkes, Rachel

    2017-01-01

    We conducted a retrospective national mortuary based study to identify all adult female homicides (18 years and older) and all child homicides (boys and girls < 18 years) in 2009 in a randomly selected, proportionate sample of mortuaries. Victim, perpetrator and crime data were collected in three processes: from the mortuary register, the autopsy report and from police with the identification of sexual homicides validated across the data collection processes. Among the 2670 (95% CI: 2311-2979) adult women killed in 2009, 494 (95% CI: 406-574) were identified as sexual homicides which was 19.8% (95% CI: 17.6-22.0) of all adult female homicides and among 1277 (95% CI: 1091-1462) children killed in SA, sexual homicides were found in 104 (95% CI: 77-132) of the child homicides which was 8.7% (95% CI: 10.9-11.2%) of these murders. Strangulation was the most common cause of death for both children and adult females. A distinct age and sex pattern was found among children with only 1% boy child death identified as a sexual homicide and 92% of all the child sexual homicides were among girls. Strangulation was the most common manner of death among children (35.5%) and perpetrators were seldom strangers. However, no difference in the proportion of convictions between the sexual homicides and non-sexual homicides were found for both adult females and children. Rape homicide is not a rare event in South Africa, with one in five female homicides and nearly one in ten child homicides identified with an associated sexual crime. These high prevalences are amongst the highest levels reported in the literature with our study among the few reporting on the epidemiology of child sexual homicide. Reducing mortality is an important policy goal for South Africa and for the rest of the world and the prevention of female and child homicide is an important part of attaining this goal.

  20. Human rights assessment in Parc Jean Marie Vincent, Port-au-Prince, Haiti.

    PubMed

    Cullen, Kimberly A; Ivers, Louise C

    2010-12-15

    Months after a 7.0 magnitude earthquake hit Port-au-Prince, Haiti, over one million remain homeless and living in spontaneous internally displaced person (IDP) camps. Billions of dollars from aid organizations and government agencies have been pledged toward the relief effort, yet many basic human needs, including food, shelter, and sanitation, continue to be unmet. The Sphere Project, "Humanitarian Charter and Minimum Standards in Disaster Response," identifies the minimum standards to be attained in disaster response. From a human rights perspective and utilizing key indicators from the Sphere Project as benchmarks, this article reports on an assessment of the living conditions approximately 12 weeks after the earthquake in Parc Jean Marie Vincent, a spontaneous IDP camp in Port-au-Prince. A stratified random sample of households in the camp, proportionate to the number of families living in each sector, was selected. Interview questions were designed to serve as "key indicators" for the Sphere Project minimum standards. A total of 486 interviews were completed, representing approximately 5% of households in each of the five sectors of the camp. Our assessment identified the relative achievements and shortcomings in the provision of relief services in Parc Jean Marie Vincent. At the time of this survey, the Sphere Project minimum standards for access to health care and quantity of water per person per day were being met. Food, shelter, sanitation, and security were below minimum accepted standard and of major concern. The formal assessment reported here was completed by September 2010, and is necessarily limited to conditions in Haiti before the cholera outbreak in October. Copyright © 2010 Cullen and Ivers. This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original author and source are credited.

  1. Factors associated with the motivation and de-motivation of health workforce in Nepal.

    PubMed

    Ghimire, J; Gupta, R P; Kumal, A B; Mahato, R K; Bhandari, R M; Thapa, N

    2013-05-01

    Health workforce plays an important role in improving the health of people but its shortage is a major problem facing Nepal. This is further compounded by prolonged absence, low motivation, and improper distribution. The objective of the study is to find out the factors determining motivation of health workforce in the public sector. A cross sectional study was conducted during September, 2012 to February, 2013. The health facilities were selected proportionately representing all the Illakas and then a simple random sampling was done to select individual facilities. Data was collected using questionnaire. The collected data was entered and analyzed in SPSS. Ethical approval was taken from the Nepal Health Research Council. More than a half (55%) of the health workers were satisfied with their current jobs and the financial benefits they acquired. The results revealed that higher age, higher education (OR:2.6; CI:1.414-4.660) and lower service duration (OR:2.567; CI:1.193-3.306) were significant factors for the motivation of health workers along with financial rewards (OR:4.706; CI:2.961-7.478), working environment (OR:2.344; CI:1.507-3.648) and opportunity for capacity development (OR:5.437; CI:3.344-8.840). The major de-motivational factors were: low remuneration (OR:3.215; CI:2.049-5.045), limited capacity development opportunity (OR:4.269; CI:2.672-6.821), poor working environment (OR:4.062; CI:2.528-6.526), non-recognition of performance (OR: 2.157; CI:1.389-3.350), and political interferences (OR:2.752; CI:1.754-4.320). Motivation of health workers is an important factor for smooth functioning of health intuitions and increased access to quality services. The good working environment, salary and other financial benefits matter greatly for enhanced performance of health workers along with additional factors.

  2. Transport of suspended and bedload sediment at eight stations in the Coeur d'Alene River basin, Idaho

    USGS Publications Warehouse

    Clark, Greg M.; Woods, Paul F.

    2000-01-01

    At most of the stations, and at the stream discharges sampled, the bedload was primarily composed of material greater than 2 millimeters in diameter, the break between sand and gravel. A predominance of sand-sized bedload was noted at only a few stations, and generally only during low stream discharge. The particle-size distribution of bedload sediment at most stations became proportionately coarser as stream discharge increased. During the peak of snowmelt runoff for water years 1999 and 2000, gravel-sized material between 2 and 64 millimeters in diameter comprised more than 70 percent of the bedload transport at most stations. However, at the station on the Coeur d’Alene River at Rose Lake, the bedload was predominantly composed of fine-grained material of less than 1 millimeter in diameter for all measured stream discharges. The slow water velocities at Rose Lake accounted for the predominance of fine-grained sediment transport.

  3. Predictors of HIV-Risk Sexual Behavior: Examining Lifetime Sexual and Physical Abuse Histories in Relation to Substance Use and Psychiatric Problem Severity Among Ex-Offenders

    PubMed Central

    Majer, John M.; Rodriquez, Jaclyn; Bloomer, Craig; Jason, Leonard A.

    2015-01-01

    Predictors of HIV-risk sexual behavior were analyzed among a sample of ex-offenders who were completing inpatient treatment for substance dependence. Hierarchical linear regression was conducted to examine increases in participants’ number of sexual partners in relation to sociodemographic characteristics, recent substance use and current psychiatric problem severity in addition to lifetime histories of sexual and physical abuse. Gender, substance use, and psychiatric problem severity predicted increases in HIV-risk sexual behaviors beyond what was predicted by abuse histories. Proportionately more women than men reported abuse histories. In addition, significantly more unprotected sexual than safer sexual practices were observed, but differences in the frequency of these practices based on lifetime abuse histories and gender were not significant. Findings suggest recent substance use and current psychiatric problem severity are risk-factors for HIV-risk sexual behavior among ex-offenders with and without lifetime abuse histories. PMID:24717831

  4. Volitional Trust, Autonomy Satisfaction, and Engagement at Work.

    PubMed

    Heyns, Marita; Rothmann, Sebastiaan

    2018-02-01

    This study tested a structural model that identifies the nature of relationships between trust, autonomy satisfaction, and personal engagement at work. A cross-sectional survey design with a convenience sample ( n = 252) was used. The Behavioral Trust Inventory, Work-Related Basic Need Satisfaction Scale, and Work Engagement Scale were administered. While reliance-based trust did not have a significant influence on engagement, disclosure-based trust in a focal leader was found to predict satisfaction of autonomy needs and employee engagement. Mediation analyses revealed that satisfaction of the need for autonomy facilitates the influence of trust on work outcomes. More specifically, disclosure (a dimension of trust) impacted engagement via autonomy satisfaction. Overall, the model explained 44% of total variance in engagement, to which the variables proportionately contributed as follows: autonomy satisfaction = 79.58%, disclosure = 18.22%, and reliance = 2.20%. The findings provide possible directions for how leaders can leverage trust to facilitate autonomy support and higher levels of engagement.

  5. Methodology Series Module 5: Sampling Strategies.

    PubMed

    Setia, Maninder Singh

    2016-01-01

    Once the research question and the research design have been finalised, it is important to select the appropriate sample for the study. The method by which the researcher selects the sample is the ' Sampling Method'. There are essentially two types of sampling methods: 1) probability sampling - based on chance events (such as random numbers, flipping a coin etc.); and 2) non-probability sampling - based on researcher's choice, population that accessible & available. Some of the non-probability sampling methods are: purposive sampling, convenience sampling, or quota sampling. Random sampling method (such as simple random sample or stratified random sample) is a form of probability sampling. It is important to understand the different sampling methods used in clinical studies and mention this method clearly in the manuscript. The researcher should not misrepresent the sampling method in the manuscript (such as using the term ' random sample' when the researcher has used convenience sample). The sampling method will depend on the research question. For instance, the researcher may want to understand an issue in greater detail for one particular population rather than worry about the ' generalizability' of these results. In such a scenario, the researcher may want to use ' purposive sampling' for the study.

  6. A simple and efficient alternative to implementing systematic random sampling in stereological designs without a motorized microscope stage.

    PubMed

    Melvin, Neal R; Poda, Daniel; Sutherland, Robert J

    2007-10-01

    When properly applied, stereology is a very robust and efficient method to quantify a variety of parameters from biological material. A common sampling strategy in stereology is systematic random sampling, which involves choosing a random sampling [corrected] start point outside the structure of interest, and sampling relevant objects at [corrected] sites that are placed at pre-determined, equidistant intervals. This has proven to be a very efficient sampling strategy, and is used widely in stereological designs. At the microscopic level, this is most often achieved through the use of a motorized stage that facilitates the systematic random stepping across the structure of interest. Here, we report a simple, precise and cost-effective software-based alternative to accomplishing systematic random sampling under the microscope. We believe that this approach will facilitate the use of stereological designs that employ systematic random sampling in laboratories that lack the resources to acquire costly, fully automated systems.

  7. Efficient sampling of complex network with modified random walk strategies

    NASA Astrophysics Data System (ADS)

    Xie, Yunya; Chang, Shuhua; Zhang, Zhipeng; Zhang, Mi; Yang, Lei

    2018-02-01

    We present two novel random walk strategies, choosing seed node (CSN) random walk and no-retracing (NR) random walk. Different from the classical random walk sampling, the CSN and NR strategies focus on the influences of the seed node choice and path overlap, respectively. Three random walk samplings are applied in the Erdös-Rényi (ER), Barabási-Albert (BA), Watts-Strogatz (WS), and the weighted USAir networks, respectively. Then, the major properties of sampled subnets, such as sampling efficiency, degree distributions, average degree and average clustering coefficient, are studied. The similar conclusions can be reached with these three random walk strategies. Firstly, the networks with small scales and simple structures are conducive to the sampling. Secondly, the average degree and the average clustering coefficient of the sampled subnet tend to the corresponding values of original networks with limited steps. And thirdly, all the degree distributions of the subnets are slightly biased to the high degree side. However, the NR strategy performs better for the average clustering coefficient of the subnet. In the real weighted USAir networks, some obvious characters like the larger clustering coefficient and the fluctuation of degree distribution are reproduced well by these random walk strategies.

  8. Methodology Series Module 5: Sampling Strategies

    PubMed Central

    Setia, Maninder Singh

    2016-01-01

    Once the research question and the research design have been finalised, it is important to select the appropriate sample for the study. The method by which the researcher selects the sample is the ‘ Sampling Method’. There are essentially two types of sampling methods: 1) probability sampling – based on chance events (such as random numbers, flipping a coin etc.); and 2) non-probability sampling – based on researcher's choice, population that accessible & available. Some of the non-probability sampling methods are: purposive sampling, convenience sampling, or quota sampling. Random sampling method (such as simple random sample or stratified random sample) is a form of probability sampling. It is important to understand the different sampling methods used in clinical studies and mention this method clearly in the manuscript. The researcher should not misrepresent the sampling method in the manuscript (such as using the term ‘ random sample’ when the researcher has used convenience sample). The sampling method will depend on the research question. For instance, the researcher may want to understand an issue in greater detail for one particular population rather than worry about the ‘ generalizability’ of these results. In such a scenario, the researcher may want to use ‘ purposive sampling’ for the study. PMID:27688438

  9. Sampling Strategies for Evaluating the Rate of Adventitious Transgene Presence in Non-Genetically Modified Crop Fields.

    PubMed

    Makowski, David; Bancal, Rémi; Bensadoun, Arnaud; Monod, Hervé; Messéan, Antoine

    2017-09-01

    According to E.U. regulations, the maximum allowable rate of adventitious transgene presence in non-genetically modified (GM) crops is 0.9%. We compared four sampling methods for the detection of transgenic material in agricultural non-GM maize fields: random sampling, stratified sampling, random sampling + ratio reweighting, random sampling + regression reweighting. Random sampling involves simply sampling maize grains from different locations selected at random from the field concerned. The stratified and reweighting sampling methods make use of an auxiliary variable corresponding to the output of a gene-flow model (a zero-inflated Poisson model) simulating cross-pollination as a function of wind speed, wind direction, and distance to the closest GM maize field. With the stratified sampling method, an auxiliary variable is used to define several strata with contrasting transgene presence rates, and grains are then sampled at random from each stratum. With the two methods involving reweighting, grains are first sampled at random from various locations within the field, and the observations are then reweighted according to the auxiliary variable. Data collected from three maize fields were used to compare the four sampling methods, and the results were used to determine the extent to which transgene presence rate estimation was improved by the use of stratified and reweighting sampling methods. We found that transgene rate estimates were more accurate and that substantially smaller samples could be used with sampling strategies based on an auxiliary variable derived from a gene-flow model. © 2017 Society for Risk Analysis.

  10. Do Regular Social Work Faculty Earn Better Student Course Evaluations than Do Adjunct Faculty or Doctoral Students?

    ERIC Educational Resources Information Center

    Thyer, Bruce A.; Myers, Laura L.; Nugent, William R.

    2011-01-01

    Nationwide, the percentage of faculty who are tenured (or in tenure-earning positions) is declining, with proportionate increases in the amount of instruction provided by adjunct and other part-time instructors, including doctoral students. These trends are mirrored within academic social work and have given rise to some concerns about the…

  11. 26 CFR 1.901-2T - Income, war profits, or excess profits tax paid or accrued (temporary).

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... amount of tax paid. (3) Direct investment. The U.S. party's proportionate share of the foreign payment or... the interest is owned by a U.S. or foreign entity. (5) Passive investment income—(i) In general. The... recognize their distributive shares of the $10 million premium income and claim a direct foreign tax credit...

  12. Reporting Conflict in the Press, by Degree of Pluralism, Newspaper Type, and Ownership: A Comparison of 83 Minnesota Newspapers, 1965 and 1979.

    ERIC Educational Resources Information Center

    Donohue, George A.; And Others

    Data from 83 Minnesota newspapers support the hypothesis that as communities become more pluralistic, their newspapers will report more conflict. Between 1965 and 1979, Minnesota saw an increase in population and proportionate increases in income from manufacturing and agriculture. During this period of growing pluralism, the amount of newspaper…

  13. 75 FR 78282 - Self-Regulatory Organizations; Chicago Board Options Exchange, Incorporated; Notice of Filing and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-15

    ... that is typically traded on the Hybrid 3.0 Platform.\\3\\ Currently, the bandwidth allowance associated... 3.0 class is proportionately reduced to [sic] by the appointment cost of the class. However, if a Market-Maker is able to submit electronic quotes in a Hybrid 3.0 class, such as a Lead Market- Maker that...

  14. Southern pulpwood production, 1958

    Treesearch

    Joe F. Christopher; Martha E. Nelson

    1959-01-01

    The pulp industry in the south is now larger than in all other parts. of the Nation combined. In the years since 1946, construction of 2S new mills and the expansion of existing mills has more than doubled plant capacity. The annual cut of pulpwood bolts has increased proportionately, and a new source of raw material has been developed from the coarse residues at...

  15. A Confirmatory Analysis of the Organ Donation Readiness Index: Measuring the Potential for Organ Donations among African Americans

    ERIC Educational Resources Information Center

    Rice, Christopher; Tamburlin, Judith

    2004-01-01

    The need for transplant exceeds the number of available organs. Antigen compatible organs are particularly scarce for African Americans because of their proportionately lower rate of donations. This study presents a measure of organ donation readiness. Examination of the factor structure and a test of weak invariance were conducted on…

  16. 26 CFR 1.521-1 - Farmers' cooperative marketing and purchasing associations; requirements for exemption under...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... thereunder. For instance, cooperative dairy companies which are engaged in collecting milk and disposing of... the producers upon the basis of either the quantity or the value of milk or of butterfat in the milk... anyother way than on such a proportionate basis, the association does not meet the requirements of the Code...

  17. 26 CFR 1.521-1 - Farmers' cooperative marketing and purchasing associations; requirements for exemption under...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... thereunder. For instance, cooperative dairy companies which are engaged in collecting milk and disposing of... the producers upon the basis of either the quantity or the value of milk or of butterfat in the milk... anyother way than on such a proportionate basis, the association does not meet the requirements of the Code...

  18. 26 CFR 1.521-1 - Farmers' cooperative marketing and purchasing associations; requirements for exemption under...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... thereunder. For instance, cooperative dairy companies which are engaged in collecting milk and disposing of... the producers upon the basis of either the quantity or the value of milk or of butterfat in the milk... anyother way than on such a proportionate basis, the association does not meet the requirements of the Code...

  19. 26 CFR 1.521-1 - Farmers' cooperative marketing and purchasing associations; requirements for exemption under...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... thereunder. For instance, cooperative dairy companies which are engaged in collecting milk and disposing of... the producers upon the basis of either the quantity or the value of milk or of butterfat in the milk... anyother way than on such a proportionate basis, the association does not meet the requirements of the Code...

  20. Sulfur we breathe

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sawyer, J.W.

    1978-03-01

    The standards set to control the level of SO/sub 2/ in the atmosphere may not be having a proportionate effect on the formation of air-borne sulfates and sulfites and thus may not be protecting us from their harmful effects. The relationship of SO/sub 2/ levels to sulfate and sulfite concentrations is a much more complex issue than is recognized by existing regulations.

  1. Atypical Hallerman-Streif syndrome: a case report.

    PubMed

    Gopakumar, Manju; Hedge, Amitha M

    2005-01-01

    Hallerman Streif syndrome is a rare congenital disorder characterized by dyscephaly, dental anomalies, proportionate nazism, hypotrichosis, cutaneous atrophy limited to the head, bilateral congenital cataracts and bilateral microphthalmia. Despite the marked craniofacial characteristics and oral findings, a relative lack of reports in the dental literature has been noted. In this article, a case of a 8 year old boy with dental problems is described.

  2. Learning Together: Lessons about School Improvement--An HMIE Report on How Schools Get Better. Second Edition

    ERIC Educational Resources Information Center

    Her Majesty's Inspectorate of Education, 2010

    2010-01-01

    Follow-through visits are a well-established part of the process of HMIE inspection of schools. Since 2003 HMIE staff and faculty have revised the arrangements for follow-through to achieve an increasingly proportionate approach. From then, their engagement with a school following inspection has been directly related to the school's overall…

  3. 75 FR 13639 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-22

    ... proportionate share limitation of paragraph (1)(A)(iii) are accounts of the immediate family of such member or person associated with a member. For purposes of this Rule, the term ``immediate family'' shall include parents, mother-in-law or father-in-law, husband or wife, children or any relative to whose support the...

  4. Sampling Large Graphs for Anticipatory Analytics

    DTIC Science & Technology

    2015-05-15

    low. C. Random Area Sampling Random area sampling [8] is a “ snowball ” sampling method in which a set of random seed vertices are selected and areas... Sampling Large Graphs for Anticipatory Analytics Lauren Edwards, Luke Johnson, Maja Milosavljevic, Vijay Gadepally, Benjamin A. Miller Lincoln...systems, greater human-in-the-loop involvement, or through complex algorithms. We are investigating the use of sampling to mitigate these challenges

  5. Work-related ladder fall fractures: identification and diagnosis validation using narrative text.

    PubMed

    Smith, Gordon S; Timmons, Robert A; Lombardi, David A; Mamidi, Dheeresh K; Matz, Simon; Courtney, Theodore K; Perry, Melissa J

    2006-09-01

    To identify ladder-related fracture injuries and determine how ladder fall fractures differ from other ladder-related injuries. Ladder-related fracture cases were identified using narrative text and coded data from workers' compensation claims. Potential cases were identified by text searches and verified with claim records. Injury characteristics were compared using proportionate injury ratios. Of 9826 ladder-related injuries, 7% resulted in fracture cases. Falls caused 89% of fractures and resulted in more medical costs and disability days than other injuries. Frequent mechanisms were ladder instability (22%) and lost footing (22%). Narrative text searches identified 17% more fractures than injury codes alone. Males were more likely to sustain a fall fracture than other injuries; construction workers were most likely, and retail workers were the least likely to sustain fractures. Fractures are an important injury from ladder falls, resulting more serious consequences than other ladder-related injuries. Text analysis can improve the quality and utility of workers compensation data by identifying and understanding injury causes. Proportionate injury ratios are also useful for making cross-group comparisons of injury experience when denominator data are not available. Greater attention to risk factors for ladder falls is needed for targeting interventions.

  6. Promoting equity to achieve maternal and child health.

    PubMed

    Thomsen, Sarah; Hoa, Dinh Thi Phuong; Målqvist, Mats; Sanneving, Linda; Saxena, Deepak; Tana, Susilowati; Yuan, Beibei; Byass, Peter

    2011-11-01

    Maternal and child mortality rates, the targets for two of the eight Millennium Development Goals, remain unacceptably high in many countries. Some countries have made significant advances in reducing deaths in pregnancy, childbirth, and childhood at the national level. However, on a sub-national basis most countries show wide disparities in health indices which are not necessarily reflected in national figures. This is a sign of inequitable access to and provision of health services. Yet there has been little attention to health equity in relation to the Millennium Development Goals. Instead, countries have focused on achieving national targets. This has led to an emphasis on utilitarian, as opposed to universalist, approaches to public health, which we discuss here. We recommend a policy of "proportionate universalism". In this approach, universal health care and a universal social policy are the ultimate goal, but in the interim actions are carried out with intensities proportionate to disadvantage. We also briefly describe an initiative that aims to promote evidence-based policy and interventions that will reduce inequity in access to maternal and child health care in China, India, Indonesia and Viet Nam. Copyright © 2011 Reproductive Health Matters. Published by Elsevier Ltd. All rights reserved.

  7. Analyses of Radiation and Mesothelioma in the US Transuranium and Uranium Registries

    PubMed Central

    Fulcher, Keri; Nagarajan, Sumitha; McCord, Stacey; Fallahian, Naz Afarin; Hoffman, Heather J.; Haver, Cary; Tolmachev, Sergei

    2013-01-01

    Objectives. We examined the relationship between radiation and excess deaths from mesothelioma among deceased nuclear workers who were part of the US Transuranium and Uranium Registries. Methods. We performed univariate analysis with SAS Version 9.1 software. We conducted proportionate mortality ratio (PMR) and proportionate cancer mortality ratio (PCMR) analyses using the National Institute for Occupational Safety and Health Life Table Analysis System with the referent group being all deaths in the United States. Results. We found a PMR of 62.40 (P < .05) and a PCMR of 46.92 (P < .05) for mesothelioma. PMRs for the 4 cumulative external radiation dose quartiles were 61.83, 57.43, 74.46, and 83.31. PCMRs were 36.16, 47.07, 51.35, and 67.73. The PMR and PCMR for trachea, bronchus, and lung cancer were not significantly elevated. Conclusions. The relationship between cumulative external radiation dose and the PMR and PCMR for mesothelioma suggests that external radiation at nuclear facilities is associated with an increased risk of mesothelioma. The lack of a significantly elevated PMR and PCMR for trachea, bronchus, and lung cancer suggests that asbestos did not confound this relationship. PMID:23409888

  8. Electromagnetic Scattering by Fully Ordered and Quasi-Random Rigid Particulate Samples

    NASA Technical Reports Server (NTRS)

    Mishchenko, Michael I.; Dlugach, Janna M.; Mackowski, Daniel W.

    2016-01-01

    In this paper we have analyzed circumstances under which a rigid particulate sample can behave optically as a true discrete random medium consisting of particles randomly moving relative to each other during measurement. To this end, we applied the numerically exact superposition T-matrix method to model far-field scattering characteristics of fully ordered and quasi-randomly arranged rigid multiparticle groups in fixed and random orientations. We have shown that, in and of itself, averaging optical observables over movements of a rigid sample as a whole is insufficient unless it is combined with a quasi-random arrangement of the constituent particles in the sample. Otherwise, certain scattering effects typical of discrete random media (including some manifestations of coherent backscattering) may not be accurately replicated.

  9. Effect of two prophylactic bolus vitamin D dosing regimens (1000 IU/day vs. 400 IU/day) on bone mineral content in new-onset and infrequently-relapsing nephrotic syndrome: a randomised clinical trial.

    PubMed

    Muske, Sravani; Krishnamurthy, Sriram; Kamalanathan, Sadish Kumar; Rajappa, Medha; Harichandrakumar, K T; Sivamurukan, Palanisamy

    2018-02-01

    To examine the efficacy of two vitamin D dosages (1000 vs. 400 IU/day) for osteoprotection in children with new-onset and infrequently-relapsing nephrotic syndrome (IFRNS) receiving corticosteroids. This parallel-group, open label, randomised clinical trial enrolled 92 children with new-onset nephrotic syndrome (NS) (n = 28) or IFRNS (n = 64) to receive 1000 IU/day (Group A, n = 46) or 400 IU/day (Group B, n = 46) vitamin D (administered as a single bolus initial supplemental dose) by block randomisation in a 1:1 allocation ratio. In Group A, vitamin D (cholecalciferol in a Calcirol® sachet) was administered in a single stat dose of 84,000 IU on Day 1 of steroid therapy (for new-onset NS), calculated for a period of 12 weeks@1000 IU/day) and 42,000 IU on Day 1 of steroid therapy (for IFRNS, calculated for a period of 6 weeks@1000 IU/day). In Group B, vitamin D (cholecalciferol in a Calcirol® sachet) was administered as a single stat dose of 33,600 IU on Day 1 of steroid therapy (for new-onset NS, calculated for a period of 12 weeks@400 IU/day) and 16,800 IU on Day 1 of steroid therapy (for IFRNS, calculated for a period of 6 weeks@400 IU/day). The proportionate change in bone mineral content (BMC) was analysed in both groups after vitamin D supplementation. Of the 92 children enrolled, 84 (n = 42 new onset, n = 42 IFRNS) completed the study and were included in the final analysis. Baseline characteristics including initial BMC, bone mineral density, cumulative prednisolone dosage and serum 25-hydroxycholecalciferol levels were comparable in the two groups. There was a greater median proportionate change in BMC in the children who received 1000 IU/day vitamin D (3.25%, IQR -1.2 to 12.4) than in those who received 400 IU/day vitamin D (1.2%, IQR -2.5 to 3.8, p = 0.048). The difference in proportionate change in BMC was only statistically significant in the combined new-onset and IFRNS, but not for IFRNS alone. There was a greater median proportionate change in serum 25-hydroxycholecalciferol, in the children who received 1000 IU/day vitamin D (20.6%, IQR 14.9-36.75) than in those who received 400 IU/day vitamin D (7.7%, IQR 3.5-18.5, p < 0.01). There was a greater median proportionate change in serum calcium in the children who received 1000 IU/day vitamin D (20%, IQR 13.1-29.0) than in those who received 400 IU/day vitamin D (11.3%, IQR 2.8-25.0, p = 0.03). Despite vitamin D therapy, BMC decreased from the baseline in 15 (32.6%) children receiving 1000 IU/day vitamin D and in 17 (36.9%) children receiving 400 IU/day vitamin D. There were no adverse effects attributable to vitamin D. The 1000 IU/day dose is marginally more effective than 400 IU/day and it is likely than an even larger dose is required. Further research is required to assess the efficacy and safety of vitamin D doses higher than 1000 IU/day.

  10. Assessment of wadeable stream resources in the driftless area ecoregion in Western Wisconsin using a probabilistic sampling design.

    PubMed

    Miller, Michael A; Colby, Alison C C; Kanehl, Paul D; Blocksom, Karen

    2009-03-01

    The Wisconsin Department of Natural Resources (WDNR), with support from the U.S. EPA, conducted an assessment of wadeable streams in the Driftless Area ecoregion in western Wisconsin using a probabilistic sampling design. This ecoregion encompasses 20% of Wisconsin's land area and contains 8,800 miles of perennial streams. Randomly-selected stream sites (n = 60) equally distributed among stream orders 1-4 were sampled. Watershed land use, riparian and in-stream habitat, water chemistry, macroinvertebrate, and fish assemblage data were collected at each true random site and an associated "modified-random" site on each stream that was accessed via a road crossing nearest to the true random site. Targeted least-disturbed reference sites (n = 22) were also sampled to develop reference conditions for various physical, chemical, and biological measures. Cumulative distribution function plots of various measures collected at the true random sites evaluated with reference condition thresholds, indicate that high proportions of the random sites (and by inference the entire Driftless Area wadeable stream population) show some level of degradation. Study results show no statistically significant differences between the true random and modified-random sample sites for any of the nine physical habitat, 11 water chemistry, seven macroinvertebrate, or eight fish metrics analyzed. In Wisconsin's Driftless Area, 79% of wadeable stream lengths were accessible via road crossings. While further evaluation of the statistical rigor of using a modified-random sampling design is warranted, sampling randomly-selected stream sites accessed via the nearest road crossing may provide a more economical way to apply probabilistic sampling in stream monitoring programs.

  11. Understanding sustained domestic violence identification in maternal and child health nurse care: process evaluation from a 2-year follow-up of the MOVE trial.

    PubMed

    Hooker, Leesa; Small, Rhonda; Taft, Angela

    2016-03-01

    To investigate factors contributing to the sustained domestic violence screening and support practices of Maternal and Child Health nurses 2 years after a randomized controlled trial. Domestic violence screening by healthcare professionals has been implemented in many primary care settings. Barriers to screening exist and screening rates remain low. Evidence for longer term integration of nurse screening is minimal. Trial outcomes showed sustained safety planning behaviours by intervention group nurses. Process evaluation in 2-year follow-up of a cluster randomized controlled trial. Evaluation included a repeat online nurse survey and 14 interviews (July-September 2013). Survey analysis included comparison of proportionate group difference between arms and between trial baseline and 2 year follow-up surveys. Framework analysis was used to assess qualitative data. Normalization Process Theory informed evaluation design and interpretation of results. Survey response was 77% (n = 123/160). Sustainability of nurse identification of domestic violence appeared to be due to greater nurse discussion and domestic violence disclosure by women, facilitated by use of a maternal health and well-being checklist. Over time, intervention group nurses used the maternal checklist more at specific maternal health visits and found the checklist the most helpful resource assisting their domestic violence work. Nurses' spoke of a degree of 'normalization' to domestic violence screening that will need constant investment to maintain. Sustainable domestic violence screening and support outcomes can be achieved in an environment of comprehensive, nurse designed and theory driven implementation. Continuing training, discussion and monitoring of domestic violence work is needed to retain sustainable practices. © 2015 John Wiley & Sons Ltd.

  12. Effect of online formative assessment on summative performance in integrated musculoskeletal system module.

    PubMed

    Mitra, Nilesh Kumar; Barua, Ankur

    2015-03-03

    The impact of web-based formative assessment practices on performance of undergraduate medical students in summative assessments is not widely studied. This study was conducted among third-year undergraduate medical students of a designated university in Malaysia to compare the effect, on performance in summative assessment, of repeated computer-based formative assessment with automated feedback with that of single paper-based formative assessment with face-to face feedback. This quasi-randomized trial was conducted among two groups of undergraduate medical students who were selected by stratified random technique from a cohort undertaking the Musculoskeletal module. The control group C (n = 102) was subjected to a paper-based formative MCQ test. The experimental group E (n = 65) was provided three online formative MCQ tests with automated feedback. The summative MCQ test scores for both these groups were collected after the completion of the module. In this study, no significant difference was observed between the mean summative scores of the two groups. However, Band 1 students from group E with higher entry qualification showed higher mean score in the summative assessment. A trivial, but significant and positive correlation (r(2) = +0.328) was observed between the online formative test scores and summative assessment scores of group E. The proportionate increase of performance in group E was found to be almost double than group C. The use of computer based formative test with automated feedback improved the performance of the students with better academic background in the summative assessment. Computer-based formative test can be explored as an optional addition to the curriculum of pre-clinical integrated medical program to improve the performance of the students with higher academic ability.

  13. Prevalence of Untreated Surgical Conditions in Rural Rwanda: A Population-Based Cross-sectional Study in Burera District.

    PubMed

    Maine, Rebecca G; Linden, Allison F; Riviello, Robert; Kamanzi, Emmanuel; Mody, Gita N; Ntakiyiruta, Georges; Kansayisa, Grace; Ntaganda, Edmond; Niyonkuru, Francine; Mubiligi, Joel M; Mpunga, Tharcisse; Meara, John G; Hedt-Gauthier, Bethany L

    2017-12-20

    In low- and middle-income countries, community-level surgical epidemiology is largely undefined. Accurate community-level surgical epidemiology is necessary for surgical health systems planning. To determine the prevalence of surgical conditions in Burera District, Northern Province, Rwanda. A cross-sectional study with a 2-stage cluster sample design (at village and household level) was carried out in Burera District in March and May 2012. A team of surgeons randomly sampled 30 villages with probability proportionate to village population size, then sampled 23 households within each village. All available household members were examined. The presence of 10 index surgical conditions (injuries/wounds, hernias/hydroceles, breast masses, neck masses, obstetric fistulas, undescended testes, hypospadias, hydrocephalus, cleft lip/palate, and clubfoot) was determined by physical examination. Prevalence was estimated overall and for each condition. Multivariable logistic regression was performed to identify factors associated with surgical conditions, accounting for the complex survey design. Of the 2165 examined individuals, 1215 (56.2%) were female. The prevalence of any surgical condition among all examined individuals was 12% (95% CI, 9.2-14.9%). Half of conditions were hernias/hydroceles (49.6%), and 44% were injuries/wounds. In multivariable analysis, children 5 years or younger had twice the odds of having a surgical condition compared with married individuals 21 to 35 years of age (reference group) (odds ratio [OR], 2.2; 95% CI, 1.26-4.04; P = .01). The oldest group, people older than 50 years, also had twice the odds of having a surgical condition compared with the reference group (married, aged >50 years: OR, 2.3; 95% CI, 1.28-4.23; P = .01; unmarried, aged >50 years: OR, 2.38; 95% CI, 1.02-5.52; P = .06). Unmarried individuals 21 to 35 years of age and unmarried individuals aged 36 to 50 years had higher odds of a surgical condition compared with the reference group (aged 21-35 years: OR, 1.68; 95% CI, 0.74-3.82; P = .22; aged 36-50 years: OR, 3.35; 95% CI, 1.29-9.11; P = .02). There was no statistical difference in odds by sex, wealth, education, or travel time to the nearest hospital. The prevalence of surgically treatable conditions in northern Rwanda was considerably higher than previously estimated modeling and surveys in comparable low- and middle-income countries. This surgical backlog must be addressed in health system plans to increase surgical infrastructure and workforce in rural Africa.

  14. A random spatial sampling method in a rural developing nation

    Treesearch

    Michelle C. Kondo; Kent D.W. Bream; Frances K. Barg; Charles C. Branas

    2014-01-01

    Nonrandom sampling of populations in developing nations has limitations and can inaccurately estimate health phenomena, especially among hard-to-reach populations such as rural residents. However, random sampling of rural populations in developing nations can be challenged by incomplete enumeration of the base population. We describe a stratified random sampling method...

  15. Age and gender differences regarding physical performance in the elderly from Barbados and Cuba.

    PubMed

    Rodrigues-Barbosa, Aline; de Miranda, Leticia Miranda; Vieira-Guimarães, Alexsander; Xavier-Corseuil, Herton; Weber-Corseuil, Marui

    2011-02-01

    Presenting physical performance tests' (PPTs) descriptive reference values and prevalence according to gender and age-group regarding a representative sample of non-institutionalised older adults (aged 60 and over) living in Bridgetown (Barbados) and Havana (Cuba). This was a cross-sectional, population-based household survey. In Bridgetown and Havana, respectively, 1,508 and 1,905 subjects were examined who had been selected by probabilistic sampling. PPTs included handgrip strength, standing balance, timed repeated "chair stand" and "pick up a pen." The results from Bridgetown and Havana showed that values (mean ± standard deviations and percentiles) for men were greater than women in handgrip strength and "chair stand" tests (p≤0.01). Increasing age led to both genders having reduced (p≤0.001) prevalence of people having better results for each test (based on chi-square). Men had proportionately better scores than women in the four tests. The data suggested that younger people and men had better physical performance. Men and women in both countries had differences regarding the prevalence of people unable to perform the tests and better test results, according to the test and age-group. The data provided information about the range of performance that can be expected from people in different ages and helped understand usual rates of change in age-groups.

  16. Near-field commercial aircraft contribution to nitrogen oxides by engine, aircraft type, and airline by individual plume sampling.

    PubMed

    Carslaw, David C; Ropkins, Karl; Laxen, Duncan; Moorcroft, Stephen; Marner, Ben; Williams, Martin L

    2008-03-15

    Nitrogen oxides (NOx) concentrations were measured in individual plumes from aircraft departing on the northern runway at Heathrow Airport in west London. Over a period of four weeks 5618 individual plumes were sampled by a chemiluminescence monitor located 180 m from the runway. Results were processed and matched with detailed aircraft movement and aircraft engine data using chromatographic techniques. Peak concentrations associated with 29 commonly used engines were calculated and found to have a good relationship with N0x emissions taken from the International Civil Aviation Organization (ICAO) databank. However, it is found that engines with higher reported NOx emissions result in proportionately lower NOx concentrations than engines with lower emissions. We show that it is likely that aircraft operational factors such as takeoff weight and aircraftthrust setting have a measurable and important effect on concentrations of N0x. For example, NOx concentrations can differ by up to 41% for aircraft using the same airframe and engine type, while those due to the same engine type in different airframes can differ by 28%. These differences are as great as, if not greater than, the reported differences in NOx emissions between different engine manufacturers for engines used on the same airframe.

  17. Reduction of display artifacts by random sampling

    NASA Technical Reports Server (NTRS)

    Ahumada, A. J., Jr.; Nagel, D. C.; Watson, A. B.; Yellott, J. I., Jr.

    1983-01-01

    The application of random-sampling techniques to remove visible artifacts (such as flicker, moire patterns, and paradoxical motion) introduced in TV-type displays by discrete sequential scanning is discussed and demonstrated. Sequential-scanning artifacts are described; the window of visibility defined in spatiotemporal frequency space by Watson and Ahumada (1982 and 1983) and Watson et al. (1983) is explained; the basic principles of random sampling are reviewed and illustrated by the case of the human retina; and it is proposed that the sampling artifacts can be replaced by random noise, which can then be shifted to frequency-space regions outside the window of visibility. Vertical sequential, single-random-sequence, and continuously renewed random-sequence plotting displays generating 128 points at update rates up to 130 Hz are applied to images of stationary and moving lines, and best results are obtained with the single random sequence for the stationary lines and with the renewed random sequence for the moving lines.

  18. Utilization of insecticide treated nets during pregnancy among postpartum women in Ibadan, Nigeria: a cross-sectional study

    PubMed Central

    2012-01-01

    Background Pregnant women are susceptible to symptomatic malaria due to invasion of the placenta by plasmodium. Malaria increases the risk of adverse pregnancy outcomes for mothers, the foetuses and newborns. The effective use of Insecticide Treated Nets (ITNs) would be of benefit to these vulnerable women. Previous studies have focused on prenatal-women but this study sought to explore the actual trend of utilization of the proven strategy across all the pregnancy stages among postpartum women in Ibadan. Methods This cross-sectional survey utilized a validated structured questionnaire for data collection. A calculated sample of 335 postpartum women was proportionately recruited from three fee-paying facilities within Ibadan, Nigeria using a simple random sampling technique. These hospitals have high client flow for maternity cases and are known for provision of care under traditional ANC model. The data collected were analyzed using descriptive and inferential statistics by means of Statistical Package of Social Sciences (SPSS) version 15. The level of significance was set at = 0.05. Results The women's age ranged between 18 and 47 years, mean age was 29.4 ± 0.8 years. Various irregularities marked the traditional model of ANC provided at the settings and no exposure to preconception care. Also, 276 (82.4%) had heard of ITNs. Antenatal clinics formed the major source of information. Low utilization and compliance rates were observed. One hundred and twenty-seven (37.9%) of the women had high knowledge of Malaria in Pregnancy (MIP) but only 70 (20.9%) demonstrated positive attitude towards the use of ITNs. Participants' educational status, family types, employment and residential areas significantly influenced ITNs utilization. Conclusions The women knew and learned about ITNs from ANC visits. Majority of the women did not own ITNs because of lack of access to free distribution. The existing traditional model of ANC was marked by irregularities and none of the women was exposed to preconception care. In addition, negative attitude in spite of increased knowledge of MIP was observed among the women. Therefore, evaluation of free distribution of ITNs is recommended. Integration of focused ANC and preconception care are advocated to promote early access to health information. PMID:22458645

  19. Interventions that effectively target Anopheles funestus mosquitoes could significantly improve control of persistent malaria transmission in south-eastern Tanzania.

    PubMed

    Kaindoa, Emmanuel W; Matowo, Nancy S; Ngowo, Halfan S; Mkandawile, Gustav; Mmbando, Arnold; Finda, Marcelina; Okumu, Fredros O

    2017-01-01

    Malaria is transmitted by many Anopheles species whose proportionate contributions vary across settings. We re-assessed the roles of Anopheles arabiensis and Anopheles funestus, and examined potential benefits of species-specific interventions in an area in south-eastern Tanzania, where malaria transmission persists, four years after mass distribution of long-lasting insecticide-treated nets (LLINs). Monthly mosquito sampling was done in randomly selected households in three villages using CDC light traps and back-pack aspirators, between January-2015 and January-2016, four years after the last mass distribution of LLINs in 2011. Multiplex polymerase chain reaction (PCR) was used to identify members of An. funestus and Anopheles gambiae complexes. Enzyme-linked immunosorbent assay (ELISA) was used to detect Plasmodium sporozoites in mosquito salivary glands, and to identify sources of mosquito blood meals. WHO susceptibility assays were done on wild caught female An. funestus s.l, and physiological ages approximated by examining mosquito ovaries for parity. A total of 20,135 An. arabiensis and 4,759 An. funestus were collected. The An. funestus group consisted of 76.6% An. funestus s.s, 2.9% An. rivulorum, 7.1% An. leesoni, and 13.4% unamplified samples. Of all mosquitoes positive for Plasmodium, 82.6% were An. funestus s.s, 14.0% were An. arabiensis and 3.4% were An. rivulorum. An. funestus and An. arabiensis contributed 86.21% and 13.79% respectively, of annual entomological inoculation rate (EIR). An. arabiensis fed on humans (73.4%), cattle (22.0%), dogs (3.1%) and chicken (1.5%), but An. funestus fed exclusively on humans. The An. funestus populations were 100% susceptible to organophosphates, pirimiphos methyl and malathion, but resistant to permethrin (10.5% mortality), deltamethrin (18.7%), lambda-cyhalothrin (18.7%) and DDT (26.2%), and had reduced susceptibility to bendiocarb (95%) and propoxur (90.1%). Parity rate was higher in An. funestus (65.8%) than An. arabiensis (44.1%). Though An. arabiensis is still the most abundant vector species here, the remaining malaria transmission is predominantly mediated by An. funestus, possibly due to high insecticide resistance and high survival probabilities. Interventions that effectively target An. funestus mosquitoes could therefore significantly improve control of persistent malaria transmission in south-eastern Tanzania.

  20. Interventions that effectively target Anopheles funestus mosquitoes could significantly improve control of persistent malaria transmission in south–eastern Tanzania

    PubMed Central

    Matowo, Nancy S.; Ngowo, Halfan S.; Mkandawile, Gustav; Mmbando, Arnold; Finda, Marcelina; Okumu, Fredros O.

    2017-01-01

    Malaria is transmitted by many Anopheles species whose proportionate contributions vary across settings. We re-assessed the roles of Anopheles arabiensis and Anopheles funestus, and examined potential benefits of species-specific interventions in an area in south-eastern Tanzania, where malaria transmission persists, four years after mass distribution of long-lasting insecticide-treated nets (LLINs). Monthly mosquito sampling was done in randomly selected households in three villages using CDC light traps and back-pack aspirators, between January-2015 and January-2016, four years after the last mass distribution of LLINs in 2011. Multiplex polymerase chain reaction (PCR) was used to identify members of An. funestus and Anopheles gambiae complexes. Enzyme-linked immunosorbent assay (ELISA) was used to detect Plasmodium sporozoites in mosquito salivary glands, and to identify sources of mosquito blood meals. WHO susceptibility assays were done on wild caught female An. funestus s.l, and physiological ages approximated by examining mosquito ovaries for parity. A total of 20,135 An. arabiensis and 4,759 An. funestus were collected. The An. funestus group consisted of 76.6% An. funestus s.s, 2.9% An. rivulorum, 7.1% An. leesoni, and 13.4% unamplified samples. Of all mosquitoes positive for Plasmodium, 82.6% were An. funestus s.s, 14.0% were An. arabiensis and 3.4% were An. rivulorum. An. funestus and An. arabiensis contributed 86.21% and 13.79% respectively, of annual entomological inoculation rate (EIR). An. arabiensis fed on humans (73.4%), cattle (22.0%), dogs (3.1%) and chicken (1.5%), but An. funestus fed exclusively on humans. The An. funestus populations were 100% susceptible to organophosphates, pirimiphos methyl and malathion, but resistant to permethrin (10.5% mortality), deltamethrin (18.7%), lambda-cyhalothrin (18.7%) and DDT (26.2%), and had reduced susceptibility to bendiocarb (95%) and propoxur (90.1%). Parity rate was higher in An. funestus (65.8%) than An. arabiensis (44.1%). Though An. arabiensis is still the most abundant vector species here, the remaining malaria transmission is predominantly mediated by An. funestus, possibly due to high insecticide resistance and high survival probabilities. Interventions that effectively target An. funestus mosquitoes could therefore significantly improve control of persistent malaria transmission in south–eastern Tanzania. PMID:28542335

  1. Sanitation and hygiene practices among primary school learners in Ngamiland district, Botswana

    NASA Astrophysics Data System (ADS)

    Thakadu, Olekae T.; Ngwenya, Barbara N.; Phaladze, Nthabiseng A.; Bolaane, Benjamin

    2018-06-01

    Improved sanitation and personal hygienic practices are considered important towards reducing the risks of spreading communicable diseases and improving public health. Diarrheal related deaths amongst adolescents are reported to be amongst the top ten for the age groups 10-19 year olds and second among the age group 10-14 year olds globally. Primary school learners in developing countries are among the most vulnerable sub-population. These mortalities and illnesses can be reduced by addressing personal hygiene among school children and simultaneously promoting better school attendance and improved learning. In order to facilitate improved health and educational outcomes, it is necessary therefore to effectively address water, sanitation and hygiene matters within the school environment. This study explored hygiene education, personal hygiene practices among learners, environmental sanitation and hygiene within three primary schools in the Ngamiland district, Botswana. From the three schools, a total sample of 285 pupils was selected using proportionate stratified random sampling technique, and 15 teachers purposively selected as key informants. Data was collected using semi-structured questionnaires with key informants and social survey instrument for learners. Results show that very few learners linked poor hygiene to the following diseases; diarrhea/upset stomach (31.7%); malaria (23%); bilharzia (16.4%), and cholera (14.8%), demonstrating low hygiene knowledge. Hygiene education in schools is infused in the curriculum, and teacher training on hygiene education is only through in-service training workshops. Regarding personal hygiene practices, over 70% of the learners indicated that they 'always' wash their hands before and after eating, with slightly over one-fifth indicating 'sometimes'. Overwhelming majority of learners dispose solid waste in dustbins (99.3%, n = 284), use refuse bags (80.8%, n = 231), open skips (64%, n = 183) and very few throw trash anywhere either on the school compound or classroom (9.1%, n = 26 and 8.7%, n = 25 respectively). The current low levels of hygiene knowledge among learners in the study area has potential to affect learners' performance at school as risky hygiene practices make them vulnerable to contracting infectious diseases and missing school. This prompts the need to think beyond the infusion approach used in schools. Extra-curricular clubs in schools should be established to promote pro-hygiene behaviors and to facilitate adolescence meaningful and sustained participation.

  2. 7 CFR Exhibit B to Subpart B of... - Grant Agreement (Public Bodies) for Site Development and/or Site Acquisition for Housing and/or...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... the financial results of each grant. Financial Reporting will be on an accrual basis. (b) Records... conditions established by the Grantor. Provided, however, that the proportionate share of any grant funds... compensating the Federal Government for its fair share of the property. The Federal share of the property shall...

  3. Spin pseudogap in the S = 1 2 chain material Sr 2 CuO 3 with impurities

    DOE PAGES

    Simutis, G.; Gvasaliya, S.; Beesetty, N. S.; ...

    2017-02-07

    Here, the low-energy magnetic excitation spectrum of the Heisenberg antiferromagnetic S = 1/2 chain system Sr 2CuO 3 with Ni and Ca impurities is studied by neutron spectroscopy. In all cases, a defect-induced spectral pseudogap is observed and shown to scale proportionately to the number of scattering centers in the spin chains.

  4. Fault-Tolerant Multiprocessor and VLSI-Based Systems.

    DTIC Science & Technology

    1987-03-15

    54590 170 Table 1: Statistics for the Benchmark Programs pages are distributed amongst the groups of the reconfigured memory in proportion to the...distances are proportional to only the logarithm of the sure that possesses relevance to a system which consists of alare nmbe ofhomgenouseleent...and comn.unication overhead resulting from faults communicating with all of the other elements in the system the network to degrade proportionately to

  5. What's Life Got to Do with It? The Role of Life Experiences in Shaping Female Community College Students' Transfer Intent in STEM Fields of Study

    ERIC Educational Resources Information Center

    Wickersham, Kelly; Wang, Xueli

    2016-01-01

    Transfer in science, technology, engineering, and math (STEM) fields from community colleges to 4-year institutions holds great policy significance in alleviating the female underrepresentation in the STEM pipeline, with proportionately more female students attending community colleges. Considering the knowledge gap on this often overlooked topic,…

  6. Synaptic Plasticity and Memory Formation.

    DTIC Science & Technology

    1992-05-14

    aniracetam which, as shown in an AFOSR sponsored experiment, prolongs the mean open time of the AMPA receptor channel (33). The effects of aniracetam ...potentiation while suppression of the between-burst hyperpolarizatlon elevated the ceiling on maximal LTP (40). The drug aniracetam , which as noted...receptors. Behav. Neural Biol. 54: 213-217, 1990. 23. Staubli, U., Kessler, M. and Lynch, G. Aniracetam has proportionately smaller effects on synapses

  7. Wildlife of southern forests habitat & management (Chapter 16): Wild Hogs

    Treesearch

    James G. Dickson; John J. Mayer; John D. Dickson

    2003-01-01

    Wild hogs or swine are medium to large-sized, stout-bodied, and proportionately short-legged hoofed mammals with thick skin covered with sparse to dense coats of coarse bristles. These animals have elongated heads and snouts ending in a disc-like pad through which the external nares open. The only other species in the southern United States that resembles the wild hog...

  8. Why Are There Proportionately More Poor Pupils Enrolled in Non-State Schools in Urban Kenya in Spite of FPE Policy?

    ERIC Educational Resources Information Center

    Oketch, Moses; Mutisya, Maurice; Ngware, Moses; Ezeh, Alex C.

    2010-01-01

    One of the conundrums of free primary education (FPE) policy in several countries in Sub-Saharan Africa is the "mushrooming" of fee-paying private schools. Several researchers have become interested in studying this phenomenon and have raised the question--does free primary education meet the needs of the poor? Emerging voices among this…

  9. Egypt: Background and U.S. Relations

    DTIC Science & Technology

    2016-02-25

    terrorism-related crimes , 14 shields the police from penalties for “proportionate use of force,” and fines journalists for contradicting the government’s...problems were excessive use of force by security forces, including unlawful killings and torture ; the suppression of civil liberties, including...for journalists with at least (as of December 2015) 20 currently detained.” 20 Alleged Murder of Italian Student in Egypt In February 2016, the

  10. Image of Nursing Profession as Perceived by Egyptian and Jordanian Undergraduate Male Nursing Students: A Comparative Study

    ERIC Educational Resources Information Center

    Ibrahim, Azza Fathi; Akel, Dalal Talat; Alzghoul, Husam Wasil Mohammed

    2015-01-01

    The hiring and maintaining of male nurses in the nursing field is a very apparent issue nowadays. Hence, there is an urgent need to promote a professional nursing image and enhance its standing in the community, especially for men. Although they have an important position in nursing, men are still proportionately in the minority. This study aimed…

  11. Inheritance of proportionate dwarfism in Angus cattle.

    PubMed

    Latter, M R; Latter, B D H; Wilkins, J F; Windsor, P A

    2006-04-01

    To determine the mode of inheritance of congenital proportionate dwarfism in Angus and Angus crossbred cattle, initially detected in two commercial beef herds in northern New South Wales. Matings of normal carrier sires to unrelated cows of diverse breeds, and of one carrier sire to his unaffected daughters. An unrelated Piedmontese bull was also mated to unaffected daughters of the carrier sires. Two carrier Angus bulls and nine unaffected daughters, all of whom were completely indistinguishable from normal animals, were purchased for controlled breeding studies under known nutritional and disease conditions. Affected and carrier individuals were examined for the presence of obvious chromosomal abnormalities. Angus dwarfism has been successfully reproduced under controlled experimental conditions over successive years using unrelated dams and is undoubtedly heritable. The high frequency of occurrence of affected individuals (23/61 = 0.38 +/- .06) among the progeny of matings of the Angus sires to unrelated females of diverse breeding is not compatible with recessive inheritance, because of the negligible frequency of proportionate dwarfism in the breeds of the dams. Both paternal and maternal transmission of the defect was demonstrated, so that imprinting in the strict sense of a gene that is only expressed when received from the male parent appears not to be involved. Tested individuals showed no evidence of gross chromosomal abnormality. Dominant autosomal inheritance with incomplete penetrance was indicated by the lack of expression of the defective gene in the two Angus sires and in three unaffected daughters who produced dwarf calves from matings to the Piedmontese bull. The mode of inheritance is that of a single autosomal dominant gene with a penetrance coefficient of 0.75 +/- 0.12, estimated from the observed incidence of 23/61 affected offspring of the two carrier Angus bulls mated to unrelated dams. Simple genetic models involving either (i) an unstable mutant which changes at high frequency to the expressed dominant dwarfing allele during gametogenesis, or (ii) a dominant allele with penetrance determined by an unlinked modifying locus, are shown to be compatible with the experimental data. Both models indicate that penetrance of the dwarfing gene may possibly be higher in matings involving carrier daughters of the two Angus bulls.

  12. Revisiting sample size: are big trials the answer?

    PubMed

    Lurati Buse, Giovanna A L; Botto, Fernando; Devereaux, P J

    2012-07-18

    The superiority of the evidence generated in randomized controlled trials over observational data is not only conditional to randomization. Randomized controlled trials require proper design and implementation to provide a reliable effect estimate. Adequate random sequence generation, allocation implementation, analyses based on the intention-to-treat principle, and sufficient power are crucial to the quality of a randomized controlled trial. Power, or the probability of the trial to detect a difference when a real difference between treatments exists, strongly depends on sample size. The quality of orthopaedic randomized controlled trials is frequently threatened by a limited sample size. This paper reviews basic concepts and pitfalls in sample-size estimation and focuses on the importance of large trials in the generation of valid evidence.

  13. Method for quantifying nitromethane in blood as a potential biomarker of halonitromethane exposure.

    PubMed

    Alwis, K Udeni; Blount, Benjamin C; Silva, Lalith K; Smith, Mitchell M; Loose, Karl-Hermann

    2008-04-01

    The cytotoxicity and genotoxicity of nitromethane and its halogenated analogues in mammals raise concerns about potential toxicity to humans. This study shows that halonitromethanes are not stable in human blood and undergo dehalogenation to form nitromethane. We quantified nitromethane in human blood using solid-phase microextraction (SPME) headspace sampling coupled with gas chromatography (GC) and high resolution mass spectrometry (HRMS). The limit of detection was 0.01 microg/L with a linear calibration curve spanning 3 orders of magnitude. This method employs isotope dilution to precisely quantify trace amounts of nitromethane (coefficient of variation <6%). At three spiked concentrations of nitromethane, method accuracy ranged from 88 to 99%. We applied this method to blood samples collected from 632 people with no known occupational exposure to nitromethane or halonitromethanes. Nitromethane was detected in all blood samples tested (range: 0.28-3.79 microg/L, median: 0.66 microg/L). Time-course experiments with trichloronitromethane- and tribromonitromethane-spiked blood showed that nitromethane was the major product formed (1 nmole tribromonitromethane formed 0.59 nmole of nitromethane, whereas 1 nmole trichloronitromethane formed 0.77 nmole nitromethane). Nitromethane may form endogenously from peroxynitrite: nitromethane concentrations increased proportionately in blood samples spiked with peroxynitrite. Blood nitromethane can be a biomarker of exposure to both nitromethane and halonitromethanes. This sensitive, accurate, and precise analytical method can be used to determine baseline blood nitromethane level in the general population. It can also be used to study the health impact from exposure to nitromethane and halonitromethanes in occupational environments and to assess trichloronitromethane (chloropicrin) exposure in chemical terrorism investigations.

  14. Leisure time physical activity in Saudi Arabia: prevalence, pattern and determining factors.

    PubMed

    Amin, Tarek Tawfik; Al Khoudair, Ali Salah; Al Harbi, Mohammad Abdulwahab; Al Ali, Ahmed Radi

    2012-01-01

    Identification of reliable predictors of leisure time physical activity (LTPA) will enable healthcare providers to intervene and change the patterns of LTPA in the population to improve community health. The objectives of this study were to determine prevalence and pattern of LTPA among adult Saudis aged 18-65 years, and to define the socio-demographic determinants that correlate with LTPA in Al-Hassa, Saudi Arabia. A cross-sectional study of 2176 adult Saudis attending urban and rural primary health care centers were selected using a multistage proportionate sampling method. Participants were personally interviewed to gather information regarding socio-demographics, physical activity pattern using the Global Physical Activity Questionnaire (GPAQ). Physical activity (PA) in each domain was expressed in metabolic equivalents (METs). The median total METs minutes/week for LTPA for both genders was 256, higher for men (636 METs minutes/week) compared to women (249 METs minutes/week). Overall, only 19.8% of the total PA was derived from LTPA. Of the sampled population 50.0% reported doing no leisure activity. Using the cut off of 600 METs-minutes/day or 150 minutes of moderate intensity over 5 or more days/week, only 21.0% of the included sample were considered as being sufficiently active and 10.4% were in the high active category with beneficial health effects. Multivariate regression analysis showed that male, younger age (<35 years), absence of chronic disease conditions and moderate level of total PA were significant predictors for being active in the LTPA domain. The prevalence and intensity of LTPA among the included sample demonstrated low levels. Nearly 80% of the included sample population did not achieve the recommended LTPA level with beneficial health effects. Female gender, urban residence and associated chronic diseases correlated with a low LTPA.

  15. Assessment of cellularity, genomic DNA yields, and technical platforms for BRAF mutational testing in thyroid fine-needle aspirate samples.

    PubMed

    Dyhdalo, Kathryn; Macnamara, Stephen; Brainard, Jennifer; Underwood, Dawn; Tubbs, Raymond; Yang, Bin

    2014-02-01

    BRAF mutation V600E (substitution Val600Glu) is a molecular signature for papillary thyroid carcinoma (PTC). Testing for BRAF mutation is clinically useful in providing prognostic prediction and facilitating accurate diagnosis of PTC in thyroid fine-needle aspirate (FNA) samples. This study assessed the correlation of cellularity with DNA yield and compared 2 technical platforms with different sensitivities in detection of BRAF mutation in cytologic specimens. Cellularity was evaluated based on groups of 10+ cells on a ThinPrep slide: 1+ (1-5 groups), 2+ (6-10 groups), 3+ (11-20 groups), and 4+ (> 20 groups). Genomic DNA was extracted from residual materials of thyroid FNAs after cytologic diagnosis. Approximately 49% of thyroid FNA samples had low cellularity (1-2+). DNA yield is proportionate with increased cellularity and increased nearly 4-fold from 1+ to 4+ cellularity in cytologic samples. When applied to BRAF mutational assay, using a cutoff of 6 groups of follicular cells with 10+ cells per group, 96.7% of cases yielded enough DNA for at least one testing for BRAF mutation. Five specimens (11.6%) with lower cellularity did not yield sufficient DNA for duplicate testing. Comparison of Sanger sequencing to allele-specific polymerase chain reaction methods shows the latter confers better sensitivity in detection of BRAF mutation, especially in limited cytologic specimens with a lower percentage of malignant cells. This study demonstrates that by using 6 groups of 10+ follicular cells as a cutoff, nearly 97% of thyroid FNA samples contain enough DNA for BRAF mutational assay. Careful selection of a molecular testing system with high sensitivity facilitates the successful conduction of molecular testing in limited cytologic specimens. Cancer (Cancer Cytopathol) 2014;122:114-22 © 2013 American Cancer Society. © 2013 American Cancer Society.

  16. qFibrosis: A fully-quantitative innovative method incorporating histological features to facilitate accurate fibrosis scoring in animal model and chronic hepatitis B patients

    PubMed Central

    Tai, Dean C.S.; Wang, Shi; Cheng, Chee Leong; Peng, Qiwen; Yan, Jie; Chen, Yongpeng; Sun, Jian; Liang, Xieer; Zhu, Youfu; Rajapakse, Jagath C.; Welsch, Roy E.; So, Peter T.C.; Wee, Aileen; Hou, Jinlin; Yu, Hanry

    2014-01-01

    Background & Aims There is increasing need for accurate assessment of liver fibrosis/cirrhosis. We aimed to develop qFibrosis, a fully-automated assessment method combining quantification of histopathological architectural features, to address unmet needs in core biopsy evaluation of fibrosis in chronic hepatitis B (CHB) patients. Methods qFibrosis was established as a combined index based on 87 parameters of architectural features. Images acquired from 25 Thioacetamide-treated rat samples and 162 CHB core biopsies were used to train and test qFibrosis and to demonstrate its reproducibility. qFibrosis scoring was analyzed employing Metavir and Ishak fibrosis staging as standard references, and collagen proportionate area (CPA) measurement for comparison. Results qFibrosis faithfully and reliably recapitulates Metavir fibrosis scores, as it can identify differences between all stages in both animal samples (p <0.001) and human biopsies (p <0.05). It is robust to sampling size, allowing for discrimination of different stages in samples of different sizes (area under the curve (AUC): 0.93–0.99 for animal samples: 1–16 mm2; AUC: 0.84–0.97 for biopsies: 10–44 mm in length). qFibrosis can significantly predict staging underestimation in suboptimal biopsies (<15 mm) and under- and over-scoring by different pathologists (p <0.001). qFibrosis can also differentiate between Ishak stages 5 and 6 (AUC: 0.73, p = 0.008), suggesting the possibility of monitoring intra-stage cirrhosis changes. Best of all, qFibrosis demonstrates superior performance to CPA on all counts. Conclusions qFibrosis can improve fibrosis scoring accuracy and throughput, thus allowing for reproducible and reliable analysis of efficacies of anti-fibrotic therapies in clinical research and practice. PMID:24583249

  17. [Comparison study on sampling methods of Oncomelania hupensis snail survey in marshland schistosomiasis epidemic areas in China].

    PubMed

    An, Zhao; Wen-Xin, Zhang; Zhong, Yao; Yu-Kuan, Ma; Qing, Liu; Hou-Lang, Duan; Yi-di, Shang

    2016-06-29

    To optimize and simplify the survey method of Oncomelania hupensis snail in marshland endemic region of schistosomiasis and increase the precision, efficiency and economy of the snail survey. A quadrate experimental field was selected as the subject of 50 m×50 m size in Chayegang marshland near Henghu farm in the Poyang Lake region and a whole-covered method was adopted to survey the snails. The simple random sampling, systematic sampling and stratified random sampling methods were applied to calculate the minimum sample size, relative sampling error and absolute sampling error. The minimum sample sizes of the simple random sampling, systematic sampling and stratified random sampling methods were 300, 300 and 225, respectively. The relative sampling errors of three methods were all less than 15%. The absolute sampling errors were 0.221 7, 0.302 4 and 0.047 8, respectively. The spatial stratified sampling with altitude as the stratum variable is an efficient approach of lower cost and higher precision for the snail survey.

  18. Smoothing the redshift distributions of random samples for the baryon acoustic oscillations: applications to the SDSS-III BOSS DR12 and QPM mock samples

    NASA Astrophysics Data System (ADS)

    Wang, Shao-Jiang; Guo, Qi; Cai, Rong-Gen

    2017-12-01

    We investigate the impact of different redshift distributions of random samples on the baryon acoustic oscillations (BAO) measurements of D_V(z)r_d^fid/r_d from the two-point correlation functions of galaxies in the Data Release 12 of the Baryon Oscillation Spectroscopic Survey (BOSS). Big surveys, such as BOSS, usually assign redshifts to the random samples by randomly drawing values from the measured redshift distributions of the data, which would necessarily introduce fiducial signals of fluctuations into the random samples, weakening the signals of BAO, if the cosmic variance cannot be ignored. We propose a smooth function of redshift distribution that fits the data well to populate the random galaxy samples. The resulting cosmological parameters match the input parameters of the mock catalogue very well. The significance of BAO signals has been improved by 0.33σ for a low-redshift sample and by 0.03σ for a constant-stellar-mass sample, though the absolute values do not change significantly. Given the precision of the measurements of current cosmological parameters, it would be appreciated for the future improvements on the measurements of galaxy clustering.

  19. Massive glutamine cyclization to pyroglutamic acid in human serum discovered using NMR spectroscopy.

    PubMed

    Nagana Gowda, G A; Gowda, Yashas N; Raftery, Daniel

    2015-04-07

    Glutamine is one of the most abundant metabolites in blood and is a precursor as well as end product central to numerous important metabolic pathways. A number of surprising and unexpected roles for glutamine, including cancer cell glutamine addiction discovered recently, stress the importance of accurate analysis of glutamine concentrations for understanding its role in health and numerous diseases. Utilizing a recently developed NMR approach that offers access to an unprecedented number of quantifiable blood metabolites, we have identified a surprising glutamine cyclization to pyroglutamic acid that occurs during protein removal. Intact, ultrafiltered and protein precipitated samples from the same pool of human serum were comprehensively investigated using (1)H NMR spectroscopy at 800 MHz to detect and quantitatively evaluate the phenomenon. Interestingly, although glutamine cyclization occurs in both ultrafiltered and protein precipitated serum, the cyclization was not detected in intact serum. Strikingly, due to cyclization, the apparent serum glutamine level drops by up to 75% and, concomitantly, the pyroglutamic acid level increases proportionately. Further, virtually under identical conditions, the magnitude of cyclization is vastly different for different portions of samples from the same pool of human serum. However, the sum of glutamine and pyroglutamic acid concentrations in each sample remains the same for all portions. These unexpected findings indicate the importance of considering the sum of apparent glutamine and pyroglutamic acid levels, obtained from the contemporary analytical methods, as the actual blood glutamine level for biomarker discovery and biological interpretations.

  20. Identification of morphological biosignatures in Martian analogue field specimens using in situ planetary instrumentation.

    PubMed

    Pullan, Derek; Westall, Frances; Hofmann, Beda A; Parnell, John; Cockell, Charles S; Edwards, Howell G M; Villar, Susana E Jorge; Schröder, Christian; Cressey, Gordon; Marinangeli, Lucia; Richter, Lutz; Klingelhöfer, Göstar

    2008-02-01

    We have investigated how morphological biosignatures (i.e., features related to life) might be identified with an array of viable instruments within the framework of robotic planetary surface operations at Mars. This is the first time such an integrated lab-based study has been conducted that incorporates space-qualified instrumentation designed for combined in situ imaging, analysis, and geotechnics (sampling). Specimens were selected on the basis of feature morphology, scale, and analogy to Mars rocks. Two types of morphological criteria were considered: potential signatures of extinct life (fossilized microbial filaments) and of extant life (crypto-chasmoendolithic microorganisms). The materials originated from a variety of topical martian analogue localities on Earth, including impact craters, high-latitude deserts, and hydrothermal deposits. Our in situ payload included a stereo camera, microscope, Mössbauer spectrometer, and sampling device (all space-qualified units from Beagle 2), and an array of commercial instruments, including a multi-spectral imager, an X-ray spectrometer (calibrated to the Beagle 2 instrument), a micro-Raman spectrometer, and a bespoke (custom-designed) X-ray diffractometer. All experiments were conducted within the engineering constraints of in situ operations to generate realistic data and address the practical challenges of measurement. Our results demonstrate the importance of an integrated approach for this type of work. Each technique made a proportionate contribution to the overall effectiveness of our "pseudopayload" for biogenic assessment of samples yet highlighted a number of limitations of current space instrument technology for in situ astrobiology.

  1. Occurrence and spatial distribution of chemical contaminants in edible fish species collected from UK and proximate marine waters.

    PubMed

    Fernandes, A R; Mortimer, D; Holmes, M; Rose, M; Zhihua, L; Huang, X; Smith, F; Panton, S; Marshall, L

    2018-05-01

    The occurrence of a range of regulated and emerging organic environmental contaminants was investigated in 182 samples of edible marine fish sampled mainly from UK marine regions, but extending northerly to the coast of Norway and south to the Algarve. These species (sprats, mackerel, turbot, halibut, herring, grey mullet, sea bass, grey mullet, sardines, etc.) are among those considered to be at the highest risk of contamination with regulated contaminants such as polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs, dioxins), and polychlorinated biphenyls (PCBs), but the occurrence of polybrominated diphenylethers (PBDEs) and polybrominated biphenyls (PBBs) was also investigated. Sub-sets of samples (50-75) were also analysed for emerging contaminants: polychlorinated naphthalenes (PCNs), polybrominated and mixed halogenated dibenzo-p-dioxins, dibenzofurans and biphenyls (PBDD/Fs, PXDD/Fs and PXBs) and perfluoroalkyl substances (PFAS). Contaminant occurrence varied with species and location, but all measured contaminants were detected, with sprats, sea bass, sardines, mackerel, and herring showing higher tissue concentrations. The concentrations of the different contaminants in the various samples were mapped utilising the GPS coordinate data of the capture locations to visualise spatial distribution levels. In terms of catch location, fish sampled from the coasts of southern Britain, north-western France and the Irish Sea appeared to contain proportionately higher levels of some contaminants - e.g. samples from the Irish Sea tended to show higher PCN concentrations, whereas higher levels of PCBs were observed in some fish sampled off the coasts of northern France. Similarly, samples of mullet from the southeast coast of UK showed much higher concentrations of BDE-99 than the other regions. In terms of occurrence trends, PCDD/F and PCB concentrations show a modest decline over the last decade but where limited background data is available for emerging contaminants, there is no evidence of downward trends. Copyright © 2018 Elsevier Ltd. All rights reserved.

  2. Determination of the influence of dispersion pattern of pesticide-resistant individuals on the reliability of resistance estimates using different sampling plans.

    PubMed

    Shah, R; Worner, S P; Chapman, R B

    2012-10-01

    Pesticide resistance monitoring includes resistance detection and subsequent documentation/ measurement. Resistance detection would require at least one (≥1) resistant individual(s) to be present in a sample to initiate management strategies. Resistance documentation, on the other hand, would attempt to get an estimate of the entire population (≥90%) of the resistant individuals. A computer simulation model was used to compare the efficiency of simple random and systematic sampling plans to detect resistant individuals and to document their frequencies when the resistant individuals were randomly or patchily distributed. A patchy dispersion pattern of resistant individuals influenced the sampling efficiency of systematic sampling plans while the efficiency of random sampling was independent of such patchiness. When resistant individuals were randomly distributed, sample sizes required to detect at least one resistant individual (resistance detection) with a probability of 0.95 were 300 (1%) and 50 (10% and 20%); whereas, when resistant individuals were patchily distributed, using systematic sampling, sample sizes required for such detection were 6000 (1%), 600 (10%) and 300 (20%). Sample sizes of 900 and 400 would be required to detect ≥90% of resistant individuals (resistance documentation) with a probability of 0.95 when resistant individuals were randomly dispersed and present at a frequency of 10% and 20%, respectively; whereas, when resistant individuals were patchily distributed, using systematic sampling, a sample size of 3000 and 1500, respectively, was necessary. Small sample sizes either underestimated or overestimated the resistance frequency. A simple random sampling plan is, therefore, recommended for insecticide resistance detection and subsequent documentation.

  3. Investigating the Randomness of Numbers

    ERIC Educational Resources Information Center

    Pendleton, Kenn L.

    2009-01-01

    The use of random numbers is pervasive in today's world. Random numbers have practical applications in such far-flung arenas as computer simulations, cryptography, gambling, the legal system, statistical sampling, and even the war on terrorism. Evaluating the randomness of extremely large samples is a complex, intricate process. However, the…

  4. JPRS Report, West Europe.

    DTIC Science & Technology

    1987-07-10

    movement, it strongly criticized the "androcratic" composition of the Central Political Organizational Committee (only seven female members) and the...to elect the Central Committee proportionately by sex. That is, if women form 30 or 40 percent of the party’s members, females will...has a solarium and well-equipped bodybuilding club. "And it is almost impossible to find a lot for a summer cabin," sighs an individual on a brisk

  5. Understanding the Impact of Academic Support Programs on First-Time Bar Passage for Students at the University of Idaho College of Law

    ERIC Educational Resources Information Center

    Albertson, Helen

    2013-01-01

    As racial and ethnic population changes occur in the United States these same changes should be reflected in the legal community of lawyers and judges. Although Black and Hispanic populations have been increasing over the past 30 years in the United States, this same proportionate increase has not occurred in the American Bar Association (ABA)…

  6. The Proportionate Costs of Title I Supplemental Educational Services: Effect of Time in Treatment on Student Achievement

    ERIC Educational Resources Information Center

    Cooper, Rebeca Ann

    2014-01-01

    Since the inception of the No Child Left Behind (NCLB) act (P.L. 107-110), the debate continues regarding supplemental education service (SES) providers and their effectiveness in improving student achievement. NCLB requires districts to use an amount equal to at least 20% out if their Title I, Part A funds (U.S.D.E, 2011) to offer SES to students…

  7. Cardiovascular Adaptation to Stress

    DTIC Science & Technology

    1979-05-01

    sympathetic activity, suited in a proportionately larger increase in cardiac The concept that the background level of sympathetic output than arterial...simultaneously be reduced during disten- hypoxia. flow autoregulation occurred. In these con- sion. This concept is supported by the work of Levy et al. scious...of Pharmacology, University of Texa Healh Science Center, San Antonio, Texas 78284 S’rm r, H. 0., D. F. PlTERSON, AND V. S. BISHOP. Car- their

  8. Musculature of facial scent glands in the muntjac.

    PubMed Central

    Barrette, C

    1976-01-01

    The muscles associated with the very large preorbital glands of muntjacs (Muntiacus) are described. Although the two muntjac fawns examined were only 10 days old, their muscles were proportionately larger than those in adult specimens of North American cervids. A muscle, not found in North American cervids, but well developed in muntjacs, is probably responsible for the eversion of muntjacs' preorbital glands. Images Fig. 1 Fig. 2 Fig. 3 PMID:977477

  9. An all-woman crew to Mars: a radical proposal

    NASA Technical Reports Server (NTRS)

    Landis, G. A.

    2000-01-01

    It is logical to propose that if a human mission is flown to Mars, it should be composed of an entirely female crew. On the average, women have lower mass and take less volume than males, and use proportionately less consumables. In addition, sociological research indicates that a female crew may have a preferable interpersonal dynamic, and be likely to choose non-confrontational approaches to solve interpersonal problems.

  10. Designing a Forcenet Information Topology

    DTIC Science & Technology

    2004-12-01

    and limitations, but one consistent problem is that by tagging data the amount of bits needed to represent the data grows proportionately. As a...40 Frank Morning, Jr., “Smallsats Grow Up,” Aviation Week & Space Technology, December 8, 2003 41 Ibid. 32 (such as emails home or...Below are a few important points concerning a huge field of work. a. Dissimilar Redundancy and Reconstitution A growing concern within the DoD is

  11. Assessment of Stage of Change, Decisional Balance, Self-Efficacy, and Use of Processes of Change of Low-Income Parents for Increasing Servings of Fruits and Vegetables to Preschool-Aged Children

    ERIC Educational Resources Information Center

    Hildebrand, Deana A.; Betts, Nancy M.

    2009-01-01

    Objective: Use the Transtheoretical Model of Behavior Change (TTM) to determine the proportionate stage of change of low-income parents and primary caregivers (PPC) for increasing accessibility, measured as servings served, of fruits and vegetables (FV) to their preschool-aged children and evaluate response differences for theoretical constructs.…

  12. KSC-388c2096-08

    NASA Image and Video Library

    2000-05-02

    Original photo and caption dated June 22, 1988: "A dwarf wheat variety known as Yecoro Rojo flourishes in KSC's Biomass Production Chamber. Researchers are gathering information on the crop's ability to produce food, water and oxygen, and then remove carbon dioxide. The confined quarters associated with space travel require researchers to focus on smaller plants that yield proportionately large amounts of biomass. This wheat crop takes about 85 days to grow before harvest."

  13. Using novel control groups to dissect the amygdala's role in Williams syndrome.

    PubMed

    Thornton-Wells, Tricia A; Avery, Suzanne N; Blackford, Jennifer Urbano

    2011-07-01

    Williams syndrome is a neurodevelopmental disorder with an intriguing behavioral phenotype-hypersociability combined with significant non-social fears. Previous studies have demonstrated abnormalities in amygdala function in individuals with Williams syndrome compared to typically-developing controls. However, it remains unclear whether the findings are related to the atypical neurodevelopment of Williams syndrome, or are also associated with behavioral traits at the extreme end of a normal continuum. We used functional magnetic resonance imaging (fMRI) to compare amygdala blood-oxygenation-level-dependent (BOLD) responses to non-social and social images in individuals with Williams syndrome compared to either individuals with inhibited temperament (high non-social fear) or individuals with uninhibited temperament (high sociability). Individuals with Williams syndrome had larger amygdala BOLD responses when viewing the non-social fear images than the inhibited temperament control group. In contrast, when viewing both fear and neutral social images, individuals with Williams syndrome did not show smaller amygdala BOLD responses relative to the uninhibited temperament control group, but instead had amygdala responses proportionate to their sociability. These results suggest heightened amygdala response to non-social fear images is characteristic of WS, whereas, variability in amygdala response to social fear images is proportionate to, and might be explained by, levels of trait sociability.

  14. Do targets matter? A comparison of English and Welsh National Health priorities.

    PubMed

    Hauck, Katharina; Street, Andrew

    2007-03-01

    National priorities and performance management regimes in the National Health Services of England and Wales diverged following devolution, most notably with respect to the use of waiting time targets, which have been progressively strengthened in England but were abandoned in Wales in the immediate post-devolution period. We analyse routine data collected over a six-year period from three English and one Welsh hospital trust close to the English-Welsh border to ascertain whether: (a) there is evidence of differential performance over time that relates to the country where the hospital is located; (b) within each hospital, there is evidence that English and Welsh patients faced different waiting times. Over the period the English hospitals recorded increased levels of activity, undertook proportionately more day case activity, and mortality rates fell. Activity levels remained constant in Wales, the proportion of day case activity fell, proportionately more non-elective patients were admitted, and mortality rates rose. There is partial evidence that English patients faced lower waiting times than their Welsh counterparts and were more likely to be admitted within a target waiting period. The stronger performance management regime operating in England appears to have contributed to higher levels of performance in the English hospitals over the period. Copyright (c) 2006 John Wiley & Sons, Ltd.

  15. RECAL: A Computer Program for Selecting Sample Days for Recreation Use Estimation

    Treesearch

    D.L. Erickson; C.J. Liu; H. Ken Cordell; W.L. Chen

    1980-01-01

    Recreation Calendar (RECAL) is a computer program in PL/I for drawing a sample of days for estimating recreation use. With RECAL, a sampling period of any length may be chosen; simple random, stratified random, and factorial designs can be accommodated. The program randomly allocates days to strata and locations.

  16. Sample Selection in Randomized Experiments: A New Method Using Propensity Score Stratified Sampling

    ERIC Educational Resources Information Center

    Tipton, Elizabeth; Hedges, Larry; Vaden-Kiernan, Michael; Borman, Geoffrey; Sullivan, Kate; Caverly, Sarah

    2014-01-01

    Randomized experiments are often seen as the "gold standard" for causal research. Despite the fact that experiments use random assignment to treatment conditions, units are seldom selected into the experiment using probability sampling. Very little research on experimental design has focused on how to make generalizations to well-defined…

  17. Understanding and comparisons of different sampling approaches for the Fourier Amplitudes Sensitivity Test (FAST)

    PubMed Central

    Xu, Chonggang; Gertner, George

    2013-01-01

    Fourier Amplitude Sensitivity Test (FAST) is one of the most popular uncertainty and sensitivity analysis techniques. It uses a periodic sampling approach and a Fourier transformation to decompose the variance of a model output into partial variances contributed by different model parameters. Until now, the FAST analysis is mainly confined to the estimation of partial variances contributed by the main effects of model parameters, but does not allow for those contributed by specific interactions among parameters. In this paper, we theoretically show that FAST analysis can be used to estimate partial variances contributed by both main effects and interaction effects of model parameters using different sampling approaches (i.e., traditional search-curve based sampling, simple random sampling and random balance design sampling). We also analytically calculate the potential errors and biases in the estimation of partial variances. Hypothesis tests are constructed to reduce the effect of sampling errors on the estimation of partial variances. Our results show that compared to simple random sampling and random balance design sampling, sensitivity indices (ratios of partial variances to variance of a specific model output) estimated by search-curve based sampling generally have higher precision but larger underestimations. Compared to simple random sampling, random balance design sampling generally provides higher estimation precision for partial variances contributed by the main effects of parameters. The theoretical derivation of partial variances contributed by higher-order interactions and the calculation of their corresponding estimation errors in different sampling schemes can help us better understand the FAST method and provide a fundamental basis for FAST applications and further improvements. PMID:24143037

  18. Understanding and comparisons of different sampling approaches for the Fourier Amplitudes Sensitivity Test (FAST).

    PubMed

    Xu, Chonggang; Gertner, George

    2011-01-01

    Fourier Amplitude Sensitivity Test (FAST) is one of the most popular uncertainty and sensitivity analysis techniques. It uses a periodic sampling approach and a Fourier transformation to decompose the variance of a model output into partial variances contributed by different model parameters. Until now, the FAST analysis is mainly confined to the estimation of partial variances contributed by the main effects of model parameters, but does not allow for those contributed by specific interactions among parameters. In this paper, we theoretically show that FAST analysis can be used to estimate partial variances contributed by both main effects and interaction effects of model parameters using different sampling approaches (i.e., traditional search-curve based sampling, simple random sampling and random balance design sampling). We also analytically calculate the potential errors and biases in the estimation of partial variances. Hypothesis tests are constructed to reduce the effect of sampling errors on the estimation of partial variances. Our results show that compared to simple random sampling and random balance design sampling, sensitivity indices (ratios of partial variances to variance of a specific model output) estimated by search-curve based sampling generally have higher precision but larger underestimations. Compared to simple random sampling, random balance design sampling generally provides higher estimation precision for partial variances contributed by the main effects of parameters. The theoretical derivation of partial variances contributed by higher-order interactions and the calculation of their corresponding estimation errors in different sampling schemes can help us better understand the FAST method and provide a fundamental basis for FAST applications and further improvements.

  19. Spline methods for approximating quantile functions and generating random samples

    NASA Technical Reports Server (NTRS)

    Schiess, J. R.; Matthews, C. G.

    1985-01-01

    Two cubic spline formulations are presented for representing the quantile function (inverse cumulative distribution function) of a random sample of data. Both B-spline and rational spline approximations are compared with analytic representations of the quantile function. It is also shown how these representations can be used to generate random samples for use in simulation studies. Comparisons are made on samples generated from known distributions and a sample of experimental data. The spline representations are more accurate for multimodal and skewed samples and to require much less time to generate samples than the analytic representation.

  20. Methods for sample size determination in cluster randomized trials

    PubMed Central

    Rutterford, Clare; Copas, Andrew; Eldridge, Sandra

    2015-01-01

    Background: The use of cluster randomized trials (CRTs) is increasing, along with the variety in their design and analysis. The simplest approach for their sample size calculation is to calculate the sample size assuming individual randomization and inflate this by a design effect to account for randomization by cluster. The assumptions of a simple design effect may not always be met; alternative or more complicated approaches are required. Methods: We summarise a wide range of sample size methods available for cluster randomized trials. For those familiar with sample size calculations for individually randomized trials but with less experience in the clustered case, this manuscript provides formulae for a wide range of scenarios with associated explanation and recommendations. For those with more experience, comprehensive summaries are provided that allow quick identification of methods for a given design, outcome and analysis method. Results: We present first those methods applicable to the simplest two-arm, parallel group, completely randomized design followed by methods that incorporate deviations from this design such as: variability in cluster sizes; attrition; non-compliance; or the inclusion of baseline covariates or repeated measures. The paper concludes with methods for alternative designs. Conclusions: There is a large amount of methodology available for sample size calculations in CRTs. This paper gives the most comprehensive description of published methodology for sample size calculation and provides an important resource for those designing these trials. PMID:26174515

  1. Influences of sampling size and pattern on the uncertainty of correlation estimation between soil water content and its influencing factors

    NASA Astrophysics Data System (ADS)

    Lai, Xiaoming; Zhu, Qing; Zhou, Zhiwen; Liao, Kaihua

    2017-12-01

    In this study, seven random combination sampling strategies were applied to investigate the uncertainties in estimating the hillslope mean soil water content (SWC) and correlation coefficients between the SWC and soil/terrain properties on a tea + bamboo hillslope. One of the sampling strategies is the global random sampling and the other six are the stratified random sampling on the top, middle, toe, top + mid, top + toe and mid + toe slope positions. When each sampling strategy was applied, sample sizes were gradually reduced and each sampling size contained 3000 replicates. Under each sampling size of each sampling strategy, the relative errors (REs) and coefficients of variation (CVs) of the estimated hillslope mean SWC and correlation coefficients between the SWC and soil/terrain properties were calculated to quantify the accuracy and uncertainty. The results showed that the uncertainty of the estimations decreased as the sampling size increasing. However, larger sample sizes were required to reduce the uncertainty in correlation coefficient estimation than in hillslope mean SWC estimation. Under global random sampling, 12 randomly sampled sites on this hillslope were adequate to estimate the hillslope mean SWC with RE and CV ≤10%. However, at least 72 randomly sampled sites were needed to ensure the estimated correlation coefficients with REs and CVs ≤10%. Comparing with all sampling strategies, reducing sampling sites on the middle slope had the least influence on the estimation of hillslope mean SWC and correlation coefficients. Under this strategy, 60 sites (10 on the middle slope and 50 on the top and toe slopes) were enough to ensure the estimated correlation coefficients with REs and CVs ≤10%. This suggested that when designing the SWC sampling, the proportion of sites on the middle slope can be reduced to 16.7% of the total number of sites. Findings of this study will be useful for the optimal SWC sampling design.

  2. Sequential time interleaved random equivalent sampling for repetitive signal.

    PubMed

    Zhao, Yijiu; Liu, Jingjing

    2016-12-01

    Compressed sensing (CS) based sampling techniques exhibit many advantages over other existing approaches for sparse signal spectrum sensing; they are also incorporated into non-uniform sampling signal reconstruction to improve the efficiency, such as random equivalent sampling (RES). However, in CS based RES, only one sample of each acquisition is considered in the signal reconstruction stage, and it will result in more acquisition runs and longer sampling time. In this paper, a sampling sequence is taken in each RES acquisition run, and the corresponding block measurement matrix is constructed using a Whittaker-Shannon interpolation formula. All the block matrices are combined into an equivalent measurement matrix with respect to all sampling sequences. We implemented the proposed approach with a multi-cores analog-to-digital converter (ADC), whose ADC cores are time interleaved. A prototype realization of this proposed CS based sequential random equivalent sampling method has been developed. It is able to capture an analog waveform at an equivalent sampling rate of 40 GHz while sampled at 1 GHz physically. Experiments indicate that, for a sparse signal, the proposed CS based sequential random equivalent sampling exhibits high efficiency.

  3. Sampling large random knots in a confined space

    NASA Astrophysics Data System (ADS)

    Arsuaga, J.; Blackstone, T.; Diao, Y.; Hinson, K.; Karadayi, E.; Saito, M.

    2007-09-01

    DNA knots formed under extreme conditions of condensation, as in bacteriophage P4, are difficult to analyze experimentally and theoretically. In this paper, we propose to use the uniform random polygon model as a supplementary method to the existing methods for generating random knots in confinement. The uniform random polygon model allows us to sample knots with large crossing numbers and also to generate large diagrammatically prime knot diagrams. We show numerically that uniform random polygons sample knots with large minimum crossing numbers and certain complicated knot invariants (as those observed experimentally). We do this in terms of the knot determinants or colorings. Our numerical results suggest that the average determinant of a uniform random polygon of n vertices grows faster than O(e^{n^2}) . We also investigate the complexity of prime knot diagrams. We show rigorously that the probability that a randomly selected 2D uniform random polygon of n vertices is almost diagrammatically prime goes to 1 as n goes to infinity. Furthermore, the average number of crossings in such a diagram is at the order of O(n2). Therefore, the two-dimensional uniform random polygons offer an effective way in sampling large (prime) knots, which can be useful in various applications.

  4. Random bit generation at tunable rates using a chaotic semiconductor laser under distributed feedback.

    PubMed

    Li, Xiao-Zhou; Li, Song-Sui; Zhuang, Jun-Ping; Chan, Sze-Chun

    2015-09-01

    A semiconductor laser with distributed feedback from a fiber Bragg grating (FBG) is investigated for random bit generation (RBG). The feedback perturbs the laser to emit chaotically with the intensity being sampled periodically. The samples are then converted into random bits by a simple postprocessing of self-differencing and selecting bits. Unlike a conventional mirror that provides localized feedback, the FBG provides distributed feedback which effectively suppresses the information of the round-trip feedback delay time. Randomness is ensured even when the sampling period is commensurate with the feedback delay between the laser and the grating. Consequently, in RBG, the FBG feedback enables continuous tuning of the output bit rate, reduces the minimum sampling period, and increases the number of bits selected per sample. RBG is experimentally investigated at a sampling period continuously tunable from over 16 ns down to 50 ps, while the feedback delay is fixed at 7.7 ns. By selecting 5 least-significant bits per sample, output bit rates from 0.3 to 100 Gbps are achieved with randomness examined by the National Institute of Standards and Technology test suite.

  5. Optimal spatial sampling techniques for ground truth data in microwave remote sensing of soil moisture

    NASA Technical Reports Server (NTRS)

    Rao, R. G. S.; Ulaby, F. T.

    1977-01-01

    The paper examines optimal sampling techniques for obtaining accurate spatial averages of soil moisture, at various depths and for cell sizes in the range 2.5-40 acres, with a minimum number of samples. Both simple random sampling and stratified sampling procedures are used to reach a set of recommended sample sizes for each depth and for each cell size. Major conclusions from statistical sampling test results are that (1) the number of samples required decreases with increasing depth; (2) when the total number of samples cannot be prespecified or the moisture in only one single layer is of interest, then a simple random sample procedure should be used which is based on the observed mean and SD for data from a single field; (3) when the total number of samples can be prespecified and the objective is to measure the soil moisture profile with depth, then stratified random sampling based on optimal allocation should be used; and (4) decreasing the sensor resolution cell size leads to fairly large decreases in samples sizes with stratified sampling procedures, whereas only a moderate decrease is obtained in simple random sampling procedures.

  6. Chi-Squared Test of Fit and Sample Size-A Comparison between a Random Sample Approach and a Chi-Square Value Adjustment Method.

    PubMed

    Bergh, Daniel

    2015-01-01

    Chi-square statistics are commonly used for tests of fit of measurement models. Chi-square is also sensitive to sample size, which is why several approaches to handle large samples in test of fit analysis have been developed. One strategy to handle the sample size problem may be to adjust the sample size in the analysis of fit. An alternative is to adopt a random sample approach. The purpose of this study was to analyze and to compare these two strategies using simulated data. Given an original sample size of 21,000, for reductions of sample sizes down to the order of 5,000 the adjusted sample size function works as good as the random sample approach. In contrast, when applying adjustments to sample sizes of lower order the adjustment function is less effective at approximating the chi-square value for an actual random sample of the relevant size. Hence, the fit is exaggerated and misfit under-estimated using the adjusted sample size function. Although there are big differences in chi-square values between the two approaches at lower sample sizes, the inferences based on the p-values may be the same.

  7. Health plan auditing: 100-percent-of-claims vs. random-sample audits.

    PubMed

    Sillup, George P; Klimberg, Ronald K

    2011-01-01

    The objective of this study was to examine the relative efficacy of two different methodologies for auditing self-funded medical claim expenses: 100-percent-of-claims auditing versus random-sampling auditing. Multiple data sets of claim errors or 'exceptions' from two Fortune-100 corporations were analysed and compared to 100 simulated audits of 300- and 400-claim random samples. Random-sample simulations failed to identify a significant number and amount of the errors that ranged from $200,000 to $750,000. These results suggest that health plan expenses of corporations could be significantly reduced if they audited 100% of claims and embraced a zero-defect approach.

  8. The study of combining Latin Hypercube Sampling method and LU decomposition method (LULHS method) for constructing spatial random field

    NASA Astrophysics Data System (ADS)

    WANG, P. T.

    2015-12-01

    Groundwater modeling requires to assign hydrogeological properties to every numerical grid. Due to the lack of detailed information and the inherent spatial heterogeneity, geological properties can be treated as random variables. Hydrogeological property is assumed to be a multivariate distribution with spatial correlations. By sampling random numbers from a given statistical distribution and assigning a value to each grid, a random field for modeling can be completed. Therefore, statistics sampling plays an important role in the efficiency of modeling procedure. Latin Hypercube Sampling (LHS) is a stratified random sampling procedure that provides an efficient way to sample variables from their multivariate distributions. This study combines the the stratified random procedure from LHS and the simulation by using LU decomposition to form LULHS. Both conditional and unconditional simulations of LULHS were develpoed. The simulation efficiency and spatial correlation of LULHS are compared to the other three different simulation methods. The results show that for the conditional simulation and unconditional simulation, LULHS method is more efficient in terms of computational effort. Less realizations are required to achieve the required statistical accuracy and spatial correlation.

  9. A new species of long-legged terrestrial Terrapotamon Ng, 1986 (Crustacea: Brachyura: Potamidae) from limestone formations in Satun, southern Thailand.

    PubMed

    Lheknim, Vachira; Ng, Peter K L

    2016-11-27

    A new species of terrestrial potamid crab, Terrapotamon longitarsus, is described from limestone hills in Satun Province in southern Thailand. It is easily distinguished from other Terrapotamon species by its conspicuously long ambulatory legs (all congeners have proportionately short legs), relatively smooth dorsal surface of carapace, transversely narrow male thoracic sternites 1-4, and a characteristically structured male first gonopod.

  10. An Analysis of Nepalese Government’s Counter Insurgency Operations (1996-2006)

    DTIC Science & Technology

    2008-01-01

    commercialisation of education should be stopped. 36. Inflation should be checked. Wages should be increased proportionate to inflation. Essential...34 ACKNOWLEDGEMENT I would like to thank Assistant Professor Erin M. Simpson, Dr. Eric Y. Shibuya, and Col Anthony Abati for their time and patience educating me...be eliminated. 41 22. All languages and dialects should be given equal opportunities to prosper. The right to education in the mother tongue up to

  11. 26 CFR 20.2031-8 - Valuation of certain life insurance and annuity contracts; valuation of shares in an open-end...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Interpolated terminal reserve at date of Z's death 13,510.33 Two-thirds of gross premium (2/3×$2,811) 1,874.00... decedent's death the proportionate part of the gross premium last paid before the date of the decedent's... and at a time when Z's wife was 35 years of age. The gross annual premium is $2,811 and the decedent...

  12. Hemoglobin status of non-school going adolescent girls in three districts of Orissa, India.

    PubMed

    Bulliyy, Gandham; Mallick, Gitanjali; Sethy, Girija Sankar; Kar, Santanu Kumar

    2007-01-01

    Anemia is a major public health problem in young children and pregnant women in SouthEast Asia, but a paucity of data on anemia in adolescent girls in India. Studies are lacking on the entire non-school going adolescent population. To determine the prevalence of anemia in non-school going adolescent girls and the association between hemoglobin (Hb) concentration and socioeconomic and nutritional factors. A cross-sectional community study conducted on a sample of 1937 healthy adolescent girls aged 11-19 years from three districts of Orissa, India. Sample size was determined using a probability proportionate to size cluster sampling. The adolescent girls were interviewed and anthropometric measurements were collected. The Hb estimation was carried out in capillary blood samples using the cyanmethemoglobin method. Anemia and nutritional status were evaluated according to standard procedures. The mean Hb concentration was 9.7 +/- 1.4 g/dL (range, 4.5-13.4 g/dL). Of the total adolescent girls, 1869 (96.5%) were anemic (Hb < 12.0 g/dL), of which, 45.2%, 46.9% and 4.4% had mild, moderate, and severe anemia, respectively. A significant curvilinear relation was found between Hb concentration and age, with the nadir of the curve occurring in the 12-14 years age group. Girls from Bargarh district had significantly lower mean Hb levels than those from the Jajpur and Khurda districts. Significant positive associations were found between Hb concentration and pre-menarche, community, education levels of girls and their parents' family income, body mass index, and mid-upper arm circumference. This study revealed that prevalence of anemia was extremely high in non-school going adolescent girls (most were moderately anemic) and stressed the need for more research and public health interventions.

  13. SEM-EDX analysis in the source apportionment of particulate matter on Hypogymnia physodes lichen transplants around the Cu smelter and former mining town of Karabash, South Urals, Russia.

    PubMed

    Williamson, B J; Mikhailova, I; Purvis, O W; Udachin, V

    2004-04-25

    Scanning electron microscopy with energy-dispersive X-ray analysis (SEM-EDX) of particulate matter on lichen transplant thalli (Hypogymnia physodes) was assessed as a complementary technique to wet chemical analysis for source apportionment of airborne contaminants. Transplants (2 month exposure) stationed in the Cu smelter and former mining town of Karabash were compared with those from a control site 30 km south. Particulate matter in Karabash samples (715 analyses) showed higher levels of S, Pb, Cu, Sn and Zn compared with the control (598 analyses). Complex element associations among the particles confounded detailed mineralogical identifications, and therefore a simplified particle classification scheme was devised for source apportionment. Karabash samples contained high levels of particles classified as mining-related (MRP), and these were also identified in control samples, indicating wide spatial dispersion from the smelter and highlighting the sensitivity of the method. It was noted that MRP <2.5-microm diameter were poorly represented on lichen surfaces suggesting this may limit the usefulness of Hypogymnia transplants as proxies when assessing human health impacts from airborne particulates. Analyses of the lichen thallus surface (away from surface particulates) revealed high levels of Cu, Zn, Fe and Pb associated with organics in the Karabash samples compared with the control, with a proportionate loss of K, interpreted as being due to a stress-related increase in cell membrane permeability. This type of analysis may provide a novel SEM-EDX-based method for assessing lichen vitality. The techniques developed are presented and further implications of the study are discussed.

  14. "Non-Contact Ultrasonic Treatment of Metals in a Magnetic Field"

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ludtka, Gerard Michael; Wilgen, John B; Kisner, Roger A

    2007-01-01

    A concept has been originated for non-contact ultrasonic treatment of metals based on the use of an induction coil located in a high-field superconducting magnet. An advantage of using a high magnetic field environment (> 9 T) is that this allows the induced surface current in the sample to be decreased proportionately. As a result, the incidental induction heating associated with the use of the EMAT (Electromagnetic Acoustical Transducer) is greatly reduced, which improves the energy efficiency of the EMAT approach. The method can be coupled with high-field magnetic processing, but can also be used where only ultrasonic treatment ismore » beneficial. In the proof-of-principle experiments, a high-field EMAT was used for non-contact ultrasonic processing of aluminum samples during solidification. The magnetic field for the EMAT was supplied by a high-field (20 Tesla) resistive magnet, and the current was provided by an induction coil. This resulted in a highly efficient EMAT that delivered 0.5 MPa (~5 atmospheres) of acoustic drive to the surface of the sample while coupling less than 100 watts of incidental induction heating. The exceptionally high energy efficiency of the electromagnetic transducer is due to the use of the high magnetic field, which reduces the current needed to achieve the same acoustic pressure. In these initial experiments, aluminum samples of A356 alloy were heated to the liquid state and allowed to solidify at a controlled cooling rate while subjected to the non-contact ultrasonic stimulation (0.5 MPa @ 165 kHz) provided by an induction coil located within the 200 mm (~8-inch) bore of a 20-T Bitter resistive magnet.« less

  15. Stool Microbiome and Metabolome Differences between Colorectal Cancer Patients and Healthy Adults

    PubMed Central

    Weir, Tiffany L.; Manter, Daniel K.; Sheflin, Amy M.; Barnett, Brittany A.; Heuberger, Adam L.; Ryan, Elizabeth P.

    2013-01-01

    In this study we used stool profiling to identify intestinal bacteria and metabolites that are differentially represented in humans with colorectal cancer (CRC) compared to healthy controls to identify how microbial functions may influence CRC development. Stool samples were collected from healthy adults (n = 10) and colorectal cancer patients (n = 11) prior to colon resection surgery at the University of Colorado Health-Poudre Valley Hospital in Fort Collins, CO. The V4 region of the 16s rRNA gene was pyrosequenced and both short chain fatty acids and global stool metabolites were extracted and analyzed utilizing Gas Chromatography-Mass Spectrometry (GC-MS). There were no significant differences in the overall microbial community structure associated with the disease state, but several bacterial genera, particularly butyrate-producing species, were under-represented in the CRC samples, while a mucin-degrading species, Akkermansia muciniphila, was about 4-fold higher in CRC (p<0.01). Proportionately higher amounts of butyrate were seen in stool of healthy individuals while relative concentrations of acetate were higher in stools of CRC patients. GC-MS profiling revealed higher concentrations of amino acids in stool samples from CRC patients and higher poly and monounsaturated fatty acids and ursodeoxycholic acid, a conjugated bile acid in stool samples from healthy adults (p<0.01). Correlative analysis between the combined datasets revealed some potential relationships between stool metabolites and certain bacterial species. These associations could provide insight into microbial functions occurring in a cancer environment and will help direct future mechanistic studies. Using integrated “omics” approaches may prove a useful tool in identifying functional groups of gastrointestinal bacteria and their associated metabolites as novel therapeutic and chemopreventive targets. PMID:23940645

  16. A Scoping Review of Digital Gaming Research Involving Older Adults Aged 85 and Older.

    PubMed

    Marston, Hannah R; Freeman, Shannon; Bishop, Kristen A; Beech, Christian L

    2016-06-01

    Interest in the use of digital game technologies by older adults is growing across disciplines from health and gerontology to computer science and game studies. The objective of this scoping review was to examine research evidence involving the oldest old (persons 85 years of age or greater) and digital game technology. PubMed, CINHAL, and Scopus were searched, and 46 articles were included in this review. Results highlighted that 60 percent of articles were published in gerontological journals, whereas only 8.7 percent were published in computer science journals. No studies focused directly on the oldest old population. Few studies included sample sizes greater than 100 participants. Seven primary and 34 secondary themes were identified, of which Hardware Technology and Assessment were the most common. Existing evidence demonstrates the paucity of studies engaging older adults 85 years of age and above regarding the use of digital gaming and highlights a new understudied cohort for further research focus. Recommendations for future research include intentional recruitment and proportionate representation of participants ≥85 years of age, large sample sizes, and explicit mention of specific numbers of participants ≥85 years of age, which are necessary to advance knowledge in this area. Integrating a rigorous and robust mixed-methods approach including theoretical perspectives would lend itself to further in-depth understanding and knowledge generation in this field.

  17. Control of natural microorganisms in chamomile (Chamomilla recutita L.) by gamma ray and electron beam irradiation.

    PubMed

    Al-Bachir, Mahfouz

    2017-01-01

    Microbial contamination levels and corresponding sensitivities to gamma rays (GR) and elec- tron beam (EB) irradiation were tested in chamomile (Chamomile recutta L.). Chamomile powders were treated with 10 and 20 kGy by GR and EB, respectively. Microbiological and chemical analyses were performed on controls and treated samples immediately after irradiation, and after 12 months of storage. The control samples of chamomile exhibited rather high microbiological contamination, exceeding the levels of 4 log10 CFU g-1   (CFU - colony forming units) reported by national and international authorities as the maximum permissible total count level. Irradiation with GR and EB was found to cause a reduction in microbial contamination proportionate to the dose delivered. The sterilizing effect of EB on microorganisms was higher than the GR one. A dose of 10 kGy of GR and EB significantly (p < 0.05) reduced the total bacte- rial, total coliform and total fungal contamination. A dose of 20 kGy of GR significantly (p < 0.05) reduced the total bacterial and total fungal contamination, while a 20 kGy dose of EB reduced the initial bacterial, total coliform and total fungal contamination to below detection level when the analysis was carried out im- mediately after irradiation treatment or after 12 months of storage. The comparative study demonstrated that electron beam was more effective for decontamination of chamomile powder than gamma irradiation.

  18. Refraction and Ocular Biometry of Preschool Children in Shanghai, China

    PubMed Central

    He, Xiangui; You, Xiaofang; Wang, Bingjie; Tan, Hui; Zhu, Jianfeng

    2018-01-01

    Purpose To investigate the refraction and ocular biometry characteristics and to examine the prevalence of refractive errors in preschool children aged 3 to 6 years in Shanghai, China. Methods A school-based cross-sectional study was conducted in Jiading and Xuhui District, Shanghai, in 2013. We randomly selected 7 kindergartens in Jiading District and 10 kindergartens in Xuhui District, with a probability proportionate to size. The children underwent comprehensive eye examinations, including cycloplegic refraction and biometric measurements. Myopia, hyperopia, astigmatism were defined as spherical equivalent (SE) ≤ −0.50 D, SE ≥ +2.00 D, and cylindrical diopters ≤ −1.00 D. Results The mean SE for 3- to 6-year-old children was +1.20 D (standard deviation [SD] 1.05), and the mean axial length (AL) was 22.29 mm (SD 0.73). The overall prevalence of myopia and astigmatism was 3.7% and 18.3%, respectively. No difference in prevalence of astigmatism was found across age groups. There was a statistically significant association between lower cylindrical diopters and higher spherical diopters (Spearman's correlation: −0.21, P < 0.001). Conclusion Chinese children aged 3 to 6 years in the Shanghai area were mostly mildly hyperopic, with a low prevalence of myopia. Refractive astigmatism for children may be relatively stable throughout the preschool stage. Astigmatism was significantly associated with refractive error. PMID:29692930

  19. 40 CFR 761.130 - Sampling requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... sampling scheme and the guidance document are available on EPA's PCB Web site at http://www.epa.gov/pcb, or... § 761.125(c) (2) through (4). Using its best engineering judgment, EPA may sample a statistically valid random or grid sampling technique, or both. When using engineering judgment or random “grab” samples, EPA...

  20. 40 CFR 761.130 - Sampling requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... sampling scheme and the guidance document are available on EPA's PCB Web site at http://www.epa.gov/pcb, or... § 761.125(c) (2) through (4). Using its best engineering judgment, EPA may sample a statistically valid random or grid sampling technique, or both. When using engineering judgment or random “grab” samples, EPA...

  1. Misrepresenting random sampling? A systematic review of research papers in the Journal of Advanced Nursing.

    PubMed

    Williamson, Graham R

    2003-11-01

    This paper discusses the theoretical limitations of the use of random sampling and probability theory in the production of a significance level (or P-value) in nursing research. Potential alternatives, in the form of randomization tests, are proposed. Research papers in nursing, medicine and psychology frequently misrepresent their statistical findings, as the P-values reported assume random sampling. In this systematic review of studies published between January 1995 and June 2002 in the Journal of Advanced Nursing, 89 (68%) studies broke this assumption because they used convenience samples or entire populations. As a result, some of the findings may be questionable. The key ideas of random sampling and probability theory for statistical testing (for generating a P-value) are outlined. The result of a systematic review of research papers published in the Journal of Advanced Nursing is then presented, showing how frequently random sampling appears to have been misrepresented. Useful alternative techniques that might overcome these limitations are then discussed. REVIEW LIMITATIONS: This review is limited in scope because it is applied to one journal, and so the findings cannot be generalized to other nursing journals or to nursing research in general. However, it is possible that other nursing journals are also publishing research articles based on the misrepresentation of random sampling. The review is also limited because in several of the articles the sampling method was not completely clearly stated, and in this circumstance a judgment has been made as to the sampling method employed, based on the indications given by author(s). Quantitative researchers in nursing should be very careful that the statistical techniques they use are appropriate for the design and sampling methods of their studies. If the techniques they employ are not appropriate, they run the risk of misinterpreting findings by using inappropriate, unrepresentative and biased samples.

  2. The Expected Sample Variance of Uncorrelated Random Variables with a Common Mean and Some Applications in Unbalanced Random Effects Models

    ERIC Educational Resources Information Center

    Vardeman, Stephen B.; Wendelberger, Joanne R.

    2005-01-01

    There is a little-known but very simple generalization of the standard result that for uncorrelated random variables with common mean [mu] and variance [sigma][superscript 2], the expected value of the sample variance is [sigma][superscript 2]. The generalization justifies the use of the usual standard error of the sample mean in possibly…

  3. Monitoring well utility in a heterogeneous DNAPL source zone area: Insights from proximal multilevel sampler wells and sampling capture-zone modelling

    NASA Astrophysics Data System (ADS)

    McMillan, Lindsay A.; Rivett, Michael O.; Wealthall, Gary P.; Zeeb, Peter; Dumble, Peter

    2018-03-01

    Groundwater-quality assessment at contaminated sites often involves the use of short-screen (1.5 to 3 m) monitoring wells. However, even over these intervals considerable variation may occur in contaminant concentrations in groundwater adjacent to the well screen. This is especially true in heterogeneous dense non-aqueous phase liquid (DNAPL) source zones, where cm-scale contamination variability may call into question the effectiveness of monitoring wells to deliver representative data. The utility of monitoring wells in such settings is evaluated by reference to high-resolution multilevel sampler (MLS) wells located proximally to short-screen wells, together with sampling capture-zone modelling to explore controls upon well sample provenance and sensitivity to monitoring protocols. Field data are analysed from the highly instrumented SABRE research site that contained an old trichloroethene source zone within a shallow alluvial aquifer at a UK industrial facility. With increased purging, monitoring-well samples tend to a flow-weighted average concentration but may exhibit sensitivity to the implemented protocol and degree of purging. Formation heterogeneity adjacent to the well-screen particularly, alongside pump-intake position and water level, influence this sensitivity. Purging of low volumes is vulnerable to poor reproducibility arising from concentration variability predicted over the initial 1 to 2 screen volumes purged. Marked heterogeneity may also result in limited long-term sample concentration stabilization. Development of bespoke monitoring protocols, that consider screen volumes purged, alongside water-quality indicator parameter stabilization, is recommended to validate and reduce uncertainty when interpreting monitoring-well data within source zone areas. Generalised recommendations on monitoring well based protocols are also developed. A key monitoring well utility is their proportionately greater sample draw from permeable horizons constituting a significant contaminant flux pathway and hence representative fraction of source mass flux. Acquisition of complementary, high-resolution, site monitoring data, however, vitally underpins optimal interpretation of monitoring-well datasets and appropriate advancement of a site conceptual model and remedial implementation.

  4. Assessment of the effect of population and diary sampling methods on estimation of school-age children exposure to fine particles.

    PubMed

    Che, W W; Frey, H Christopher; Lau, Alexis K H

    2014-12-01

    Population and diary sampling methods are employed in exposure models to sample simulated individuals and their daily activity on each simulation day. Different sampling methods may lead to variations in estimated human exposure. In this study, two population sampling methods (stratified-random and random-random) and three diary sampling methods (random resampling, diversity and autocorrelation, and Markov-chain cluster [MCC]) are evaluated. Their impacts on estimated children's exposure to ambient fine particulate matter (PM2.5 ) are quantified via case studies for children in Wake County, NC for July 2002. The estimated mean daily average exposure is 12.9 μg/m(3) for simulated children using the stratified population sampling method, and 12.2 μg/m(3) using the random sampling method. These minor differences are caused by the random sampling among ages within census tracts. Among the three diary sampling methods, there are differences in the estimated number of individuals with multiple days of exposures exceeding a benchmark of concern of 25 μg/m(3) due to differences in how multiday longitudinal diaries are estimated. The MCC method is relatively more conservative. In case studies evaluated here, the MCC method led to 10% higher estimation of the number of individuals with repeated exposures exceeding the benchmark. The comparisons help to identify and contrast the capabilities of each method and to offer insight regarding implications of method choice. Exposure simulation results are robust to the two population sampling methods evaluated, and are sensitive to the choice of method for simulating longitudinal diaries, particularly when analyzing results for specific microenvironments or for exposures exceeding a benchmark of concern. © 2014 Society for Risk Analysis.

  5. A random sampling approach for robust estimation of tissue-to-plasma ratio from extremely sparse data.

    PubMed

    Chu, Hui-May; Ette, Ene I

    2005-09-02

    his study was performed to develop a new nonparametric approach for the estimation of robust tissue-to-plasma ratio from extremely sparsely sampled paired data (ie, one sample each from plasma and tissue per subject). Tissue-to-plasma ratio was estimated from paired/unpaired experimental data using independent time points approach, area under the curve (AUC) values calculated with the naïve data averaging approach, and AUC values calculated using sampling based approaches (eg, the pseudoprofile-based bootstrap [PpbB] approach and the random sampling approach [our proposed approach]). The random sampling approach involves the use of a 2-phase algorithm. The convergence of the sampling/resampling approaches was investigated, as well as the robustness of the estimates produced by different approaches. To evaluate the latter, new data sets were generated by introducing outlier(s) into the real data set. One to 2 concentration values were inflated by 10% to 40% from their original values to produce the outliers. Tissue-to-plasma ratios computed using the independent time points approach varied between 0 and 50 across time points. The ratio obtained from AUC values acquired using the naive data averaging approach was not associated with any measure of uncertainty or variability. Calculating the ratio without regard to pairing yielded poorer estimates. The random sampling and pseudoprofile-based bootstrap approaches yielded tissue-to-plasma ratios with uncertainty and variability. However, the random sampling approach, because of the 2-phase nature of its algorithm, yielded more robust estimates and required fewer replications. Therefore, a 2-phase random sampling approach is proposed for the robust estimation of tissue-to-plasma ratio from extremely sparsely sampled data.

  6. Violence and crime among male inpatients with severe mental illness: attempting to explain ethnic differences.

    PubMed

    Bruce, Matt; Cobb, Deborah; Clisby, Holly; Ndegwa, David; Hodgins, Sheilagh

    2014-04-01

    Studies report that in the U.K., among men with severe mental illness (SMI), those of black Caribbean ethnicity display increased risk of aggressive behaviour, criminal convictions, and schizophrenia. The study aimed to compare aggressive behaviour and criminal convictions among men with SMI of white British, black Caribbean and black African ethnicity, and to explore factors associated with differences across ethnicities. Sample 1 included 1,104 male inpatients with SMI. Sample 2 included a representative sub-sample of 165 who completed interviews, and authorized access to medical and criminal files. Ethnicity was self-ascribed. Staff-rated violence prior to admission, self-reported aggressive behaviour, and convictions for non-violent and violent crimes differed among men with SMI of different ethnicities. Relative to men with SMI of white British ethnicity, those of black African ethnicity showed decreased risk of aggressive behaviour, and those of black Caribbean ethnicity showed elevated risk of convictions for non-violent, and marginally, for violent crimes. Relative to men with SMI of black African ethnicity, those of black Caribbean ethnicity showed elevated risk of aggressive behaviour and criminal convictions. Proportionately more of the men of both black African and black Caribbean ethnicity, than those of white British ethnicity, presented schizophrenia spectrum disorders. Multivariate analyses failed to identify factors that would explain differences in aggressive behaviour, and criminal convictions across ethnic groups. Differences in four different measures of aggressive and antisocial behaviour among men with SMI of different ethnicities were observed but factors associated with these differences were not found.

  7. Conic Sampling: An Efficient Method for Solving Linear and Quadratic Programming by Randomly Linking Constraints within the Interior

    PubMed Central

    Serang, Oliver

    2012-01-01

    Linear programming (LP) problems are commonly used in analysis and resource allocation, frequently surfacing as approximations to more difficult problems. Existing approaches to LP have been dominated by a small group of methods, and randomized algorithms have not enjoyed popularity in practice. This paper introduces a novel randomized method of solving LP problems by moving along the facets and within the interior of the polytope along rays randomly sampled from the polyhedral cones defined by the bounding constraints. This conic sampling method is then applied to randomly sampled LPs, and its runtime performance is shown to compare favorably to the simplex and primal affine-scaling algorithms, especially on polytopes with certain characteristics. The conic sampling method is then adapted and applied to solve a certain quadratic program, which compute a projection onto a polytope; the proposed method is shown to outperform the proprietary software Mathematica on large, sparse QP problems constructed from mass spectometry-based proteomics. PMID:22952741

  8. Point-Sampling and Line-Sampling Probability Theory, Geometric Implications, Synthesis

    Treesearch

    L.R. Grosenbaugh

    1958-01-01

    Foresters concerned with measuring tree populations on definite areas have long employed two well-known methods of representative sampling. In list or enumerative sampling the entire tree population is tallied with a known proportion being randomly selected and measured for volume or other variables. In area sampling all trees on randomly located plots or strips...

  9. Randomized branch sampling

    Treesearch

    Harry T. Valentine

    2002-01-01

    Randomized branch sampling (RBS) is a special application of multistage probability sampling (see Sampling, environmental), which was developed originally by Jessen [3] to estimate fruit counts on individual orchard trees. In general, the method can be used to obtain estimates of many different attributes of trees or other branched plants. The usual objective of RBS is...

  10. Deterministic multidimensional nonuniform gap sampling.

    PubMed

    Worley, Bradley; Powers, Robert

    2015-12-01

    Born from empirical observations in nonuniformly sampled multidimensional NMR data relating to gaps between sampled points, the Poisson-gap sampling method has enjoyed widespread use in biomolecular NMR. While the majority of nonuniform sampling schemes are fully randomly drawn from probability densities that vary over a Nyquist grid, the Poisson-gap scheme employs constrained random deviates to minimize the gaps between sampled grid points. We describe a deterministic gap sampling method, based on the average behavior of Poisson-gap sampling, which performs comparably to its random counterpart with the additional benefit of completely deterministic behavior. We also introduce a general algorithm for multidimensional nonuniform sampling based on a gap equation, and apply it to yield a deterministic sampling scheme that combines burst-mode sampling features with those of Poisson-gap schemes. Finally, we derive a relationship between stochastic gap equations and the expectation value of their sampling probability densities. Copyright © 2015 Elsevier Inc. All rights reserved.

  11. Dependence of vestibular reactions on frequency of action of sign-variable accelerations

    NASA Technical Reports Server (NTRS)

    Lapayev, E. V.; Vorobyev, O. A.; Ivanov, V. V.

    1980-01-01

    It was revealed that during the tests with continuous action of sign variable Coriolis acceleration the development of kinetosis was proportionate to the time of head inclinations in the range of 1 to 4 seconds while illusions of rocking in sagittal plane was more expressed in fast inclinations. The obtained data provided the evidence of sufficient dependence of vestibulovegetative and vestibulosensory reactions on the period of repetition of sign variable Coriolis acceleration.

  12. Environmental Statement. Oswego Steam Station. Unit 5.

    DTIC Science & Technology

    1971-12-27

    of the draft environmental statement was conducted and found to be in accord with the requirements set forth in the Environmental Policy Act of 1969...furnishcd by the Government or through GovernraenT- cncd facilities for the use of the liconse, inclumire the liccnzee’s proportionate share of the cost of...Commerce, Bureau of the Census I4 Osweqo, N.Y.. Greater Oswego Chamber of Commerce, Inc. IJ 15 Land Use and Transportation Plan - Policies for- Action

  13. An Assessment of the Extent to Which Subject Variation between the Arts and Sciences in Relation to the Award of a First Class Degree Can Explain the "Gender Gap" in UK Universities

    ERIC Educational Resources Information Center

    Woodfield, Ruth; Earl-Novell, Sarah

    2006-01-01

    There is a widely recognised national trend for girls to outperform boys at all levels of compulsory schooling. With few exceptions, however, most recent research has reported that, in relation to academic performance at university, men are proportionately over-represented at the First Class level. A number of general hypotheses have been put…

  14. The ethics of genome editing in the clinic: A dose of realism for healthcare leaders.

    PubMed

    Bubela, Tania; Mansour, Yael; Nicol, Dianne

    2017-05-01

    Genome editing technologies promise therapeutic advances for genetic diseases. We discuss the ethical and societal issues raised by these technologies, including their use in preclinical research, their potential to address mutations in somatic cells, and their potential to make germ line alterations that may be passed to subsequent generations. We call for a proportionate response from health leaders based on a realistic assessment of benefits, risks, and timelines for clinical translation.

  15. The Process of Providing Humanitarian Assistance: A Department of Defense Perspective.

    DTIC Science & Technology

    1995-09-01

    to issue verbal warnings and show force. The command later added cayenne pepper spray as another means of nondeadly force to be used after others...equipment • Ensure that troops know that cayenne pepper spray is not a substitute for deadly force (i.e., even if they have the spray, they are still...Consider methods of using proportionate force. • Obtain approval for the use of cayenne pepper spray before an operation starts. • Decide whether

  16. Majewski osteodysplastic primordial dwarfism type II (MOPD II): natural history and clinical findings.

    PubMed

    Hall, Judith G; Flora, Christina; Scott, Charles I; Pauli, Richard M; Tanaka, Kimi I

    2004-09-15

    A description of the clinical features of Majewski osteodysplastic primordial dwarfism type II (MOPD II) is presented based on 58 affected individuals (27 from the literature and 31 previously unreported cases). The remarkable features of MOPD II are: severe intrauterine growth retardation (IUGR), severe postnatal growth retardation; relatively proportionate head size at birth which progresses to true and disproportionate microcephaly; progressive disproportion of the short stature secondary to shortening of the distal and middle segments of the limbs; a progressive bony dysplasia with metaphyseal changes in the limbs; epiphyseal delay; progressive loose-jointedness with occasional dislocation or subluxation of the knees, radial heads, and hips; unusual facial features including a prominent nose, eyes which appear prominent in infancy and early childhood, ears which are proportionate, mildly dysplastic and usually missing the lobule; a high squeaky voice; abnormally, small, and often dysplastic or missing dentition; a pleasant, outgoing, sociable personality; and autosomal recessive inheritance. Far-sightedness, scoliosis, unusual pigmentation, and truncal obesity often develop with time. Some individuals seem to have increased susceptibility to infections. A number of affected individuals have developed dilation of the CNS arteries variously described as aneurysms and Moya Moya disease. These vascular changes can be life threatening, even in early years because of rupture, CNS hemorrhage, and strokes. There is variability between affected individuals even within the same family. Copyright 2004 Wiley-Liss, Inc.

  17. Disruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndrome.

    PubMed

    McIntyre, Rebecca E; Lakshminarasimhan Chavali, Pavithra; Ismail, Ozama; Carragher, Damian M; Sanchez-Andrade, Gabriela; Forment, Josep V; Fu, Beiyuan; Del Castillo Velasco-Herrera, Martin; Edwards, Andrew; van der Weyden, Louise; Yang, Fengtang; Ramirez-Solis, Ramiro; Estabel, Jeanne; Gallagher, Ferdia A; Logan, Darren W; Arends, Mark J; Tsang, Stephen H; Mahajan, Vinit B; Scudamore, Cheryl L; White, Jacqueline K; Jackson, Stephen P; Gergely, Fanni; Adams, David J

    2012-01-01

    Disruption of the centromere protein J gene, CENPJ (CPAP, MCPH6, SCKL4), which is a highly conserved and ubiquitiously expressed centrosomal protein, has been associated with primary microcephaly and the microcephalic primordial dwarfism disorder Seckel syndrome. The mechanism by which disruption of CENPJ causes the proportionate, primordial growth failure that is characteristic of Seckel syndrome is unknown. By generating a hypomorphic allele of Cenpj, we have developed a mouse (Cenpj(tm/tm)) that recapitulates many of the clinical features of Seckel syndrome, including intrauterine dwarfism, microcephaly with memory impairment, ossification defects, and ocular and skeletal abnormalities, thus providing clear confirmation that specific mutations of CENPJ can cause Seckel syndrome. Immunohistochemistry revealed increased levels of DNA damage and apoptosis throughout Cenpj(tm/tm) embryos and adult mice showed an elevated frequency of micronucleus induction, suggesting that Cenpj-deficiency results in genomic instability. Notably, however, genomic instability was not the result of defective ATR-dependent DNA damage signaling, as is the case for the majority of genes associated with Seckel syndrome. Instead, Cenpj(tm/tm) embryonic fibroblasts exhibited irregular centriole and centrosome numbers and mono- and multipolar spindles, and many were near-tetraploid with numerical and structural chromosomal abnormalities when compared to passage-matched wild-type cells. Increased cell death due to mitotic failure during embryonic development is likely to contribute to the proportionate dwarfism that is associated with CENPJ-Seckel syndrome.

  18. Classification and identification of inherited brachydactylies

    PubMed Central

    Fitch, Naomi

    1979-01-01

    A search for patterns of malformation in the brachydactylies has resulted in new ways to identify the different types. Type A-1 can be characterised by a proportionate reduction of the middle phalanges. Type B is thought to be an amputation-like defect. In type C the fourth middle phalanx is usually the longest, and type E (Riccardi and Holmes, 1974) is characterised by short metacarpals and short distal phalanges. Short stature is usually present in type A-1 and type E brachydactyly (Riccardi and Holmes, 1974) and it may be present in some individuals with brachydactyly C. As short children have short hands, it is possible that in patients with very mild expressions of brachydactyly the cause of the short stature may be overlooked. It is suggested that in every child with proportionate short stature the hands should be carefully examined. If the hands are disproportionately short, if any distal creases are missing, if there is a shortening, however mild, of any finger, if any metacarpals are short, then it is important to have ϰ-rays to look for brachydactyly A-1, C, or E. Much information is still needed. It is important in future reports to have skeletal surveys, pattern profile analyses, and to note the height of children with brachydactyly C. Most interesting of all will be when fetal limbs of each type become available for study. Images PMID:469884

  19. Specific binding of Haemophilus influenzae to minor gangliosides of human respiratory epithelial cells.

    PubMed Central

    Fakih, M G; Murphy, T F; Pattoli, M A; Berenson, C S

    1997-01-01

    Gangliosides are sialylated glycosphingolipids that serve as receptors for various bacteria. To investigate endogenous gangliosides of human respiratory epithelial cells as potential receptors for Haemophilus influenzae, three strains, including nontypeable H. influenzae (NTHI) 1479, and isogenic fimbriated (f+) and nonfimbriated (f0) H. influenzae type b 770235, were 3H labeled and overlaid on two-dimensional thin-layer chromatography (TLC) plates containing either purified HEp-2 gangliosides or murine brain gangliosides. NTHI 1479 bound exclusively to two distinct minor ganglioside doublets, with mobilities near that of GM1. These minor gangliosides comprised only 14.2 and 9.4% of the total, respectively. NTHI 1479 also bound to a distinct ganglioside of human macrophages whose chromatographic mobilities closely resemble those of one of the NTHI-binding gangliosides of HEp-2 cells. H. influenzae type b 770235 f+ and f0 each bound to a different minor HEp-2 ganglioside doublet, with proportionately weaker affinity for a major ganglioside doublet. Remarkably, none of the three strains bound to any murine brain gangliosides. Moreover, when 80 to 90% of sialic acid residues were enzymatically removed from HEp-2 gangliosides, NTHI 1479 binding was proportionately impaired, compared with untreated controls. Our findings support a role for specific gangliosides of specific cells as receptors for H. influenzae strains. Our findings further demonstrate that individual minor gangliosides possess unique biological properties. PMID:9125549

  20. Disruption of Mouse Cenpj, a Regulator of Centriole Biogenesis, Phenocopies Seckel Syndrome

    PubMed Central

    McIntyre, Rebecca E.; Lakshminarasimhan Chavali, Pavithra; Forment, Josep V.; Fu, Beiyuan; Del Castillo Velasco-Herrera, Martin; Edwards, Andrew; van der Weyden, Louise; Yang, Fengtang; Ramirez-Solis, Ramiro; Estabel, Jeanne; Gallagher, Ferdia A.; Logan, Darren W.; Arends, Mark J.; Tsang, Stephen H.; Mahajan, Vinit B.; Scudamore, Cheryl L.; White, Jacqueline K.; Jackson, Stephen P.; Gergely, Fanni; Adams, David J.

    2012-01-01

    Disruption of the centromere protein J gene, CENPJ (CPAP, MCPH6, SCKL4), which is a highly conserved and ubiquitiously expressed centrosomal protein, has been associated with primary microcephaly and the microcephalic primordial dwarfism disorder Seckel syndrome. The mechanism by which disruption of CENPJ causes the proportionate, primordial growth failure that is characteristic of Seckel syndrome is unknown. By generating a hypomorphic allele of Cenpj, we have developed a mouse (Cenpjtm/tm) that recapitulates many of the clinical features of Seckel syndrome, including intrauterine dwarfism, microcephaly with memory impairment, ossification defects, and ocular and skeletal abnormalities, thus providing clear confirmation that specific mutations of CENPJ can cause Seckel syndrome. Immunohistochemistry revealed increased levels of DNA damage and apoptosis throughout Cenpjtm/tm embryos and adult mice showed an elevated frequency of micronucleus induction, suggesting that Cenpj-deficiency results in genomic instability. Notably, however, genomic instability was not the result of defective ATR-dependent DNA damage signaling, as is the case for the majority of genes associated with Seckel syndrome. Instead, Cenpjtm/tm embryonic fibroblasts exhibited irregular centriole and centrosome numbers and mono- and multipolar spindles, and many were near-tetraploid with numerical and structural chromosomal abnormalities when compared to passage-matched wild-type cells. Increased cell death due to mitotic failure during embryonic development is likely to contribute to the proportionate dwarfism that is associated with CENPJ-Seckel syndrome. PMID:23166506

  1. Perceived risk and modal choice: risk compensation in transportation systems.

    PubMed

    Noland, R B

    1995-08-01

    A transportation mode choice analysis is performed that examines behavioral responses to perceived risk in the choice of mode for daily commute trips. This methodology provides a technique for examining, by means of disaggregate individual level data, risk-compensating effects in transportation systems. Various measures of perceived risk are examined for explaining modal choice. Other studies have described how safety regulations have resulted in increases in "driving intensity." This study defines one component of driving intensity to be the increased probability of commuting by automobile. The results show that modal shifts occur when risk perceptions for a given mode are reduced. To demonstrate potential risk-compensating effects within the transportation system, an estimate of changes in accident fatalities due to commuting is derived using rough estimates of fatalities per person-mile travelled. It is shown that a given change in the perceived risk of commuting by automobile results in a less than proportionate change in net commuting fatalities. The relative magnitude is dependent on how objective reductions in risk translate into perceived reductions in risk. This study also shows that perceived safety improvements in bicycle transportation have an aggregate elasticity value that is greater than one. This means that bicycle safety improvements attract proportionately more people to bicycle commuting (i.e. a 10% increase in safety results in a greater than 10% increase in the share of people bicycle commuting).

  2. Regional patterns of grey matter atrophy and magnetisation transfer ratio abnormalities in multiple sclerosis clinical subgroups: a voxel-based analysis study.

    PubMed

    Mallik, Shahrukh; Muhlert, Nils; Samson, Rebecca S; Sethi, Varun; Wheeler-Kingshott, Claudia A M; Miller, David H; Chard, Declan T

    2015-04-01

    In multiple sclerosis (MS), demyelination and neuro-axonal loss occur in the brain grey matter (GM). We used magnetic resonance imaging (MRI) measures of GM magnetisation transfer ratio (MTR) and volume to assess the regional localisation of reduced MTR (reflecting demyelination) and atrophy (reflecting neuro-axonal loss) in relapsing-remitting MS (RRMS), secondary progressive MS (SPMS) and primary progressive MS (PPMS). A total of 98 people with MS (51 RRMS, 28 SPMS, 19 PPMS) and 29 controls had T1-weighted volumetric and magnetisation transfer scans. SPM8 was used to undertake voxel-based analysis (VBA) of GM tissue volumes and MTR. MS subgroups were compared with controls, adjusting for age and gender. A voxel-by-voxel basis correlation analysis between MTR and volume within each subject group was performed, using biological parametric mapping. MTR reduction was more extensive than atrophy. RRMS and SPMS patients showed proportionately more atrophy in the deep GM. SPMS and PPMS patients showed proportionately greater cortical MTR reduction. RRMS patients demonstrated the most correlation of MTR reduction and atrophy in deep GM. In SPMS and PPMS patients, there was less extensive correlation. These results suggest that in the deep GM of RRMS patients, demyelination and neuro-axonal loss may be linked, while in SPMS and PPMS patients, neuro-axonal loss and demyelination may occur mostly independently. © The Author(s), 2014.

  3. Chasm in primary care provision in a universal health system: Findings from a nationally representative survey of health facilities in Malaysia

    PubMed Central

    Sivasampu, Sheamini; Khoo, Ee Ming; Mohamad Noh, Kamaliah

    2017-01-01

    Background Malaysia has achieved universal health coverage since 1980s through the expansion of direct public provision, particularly in rural areas. However, no systematic examination of the rural-urban distribution of primary care services and resources has been conducted to date for policy impact evaluation. Methods We conducted a national cross-sectional survey of 316 public and 597 private primary care clinics, selected through proportionate stratified random sampling, from June 2011 through February 2012. Using a questionnaire developed based on the World Health Organization toolkits on monitoring health systems strengthening, we examined the availability of primary care services/resources and the associations between service/resource availability and clinic ownership, locality, and patient load. Data were weighted for all analyses to account for the complex survey design and produce unbiased national estimates. Results Private primary care clinics and doctors outnumbered their public counterparts by factors of 5.6 and 3.9, respectively, but the private clinics were significantly less well-equipped with basic facilities and provided a more limited range of services. Per capita densities of primary care clinics and workforce were higher in urban areas (2.2 clinics and 15.1 providers per 10,000 population in urban areas versus 1.1 clinics and 11.7 providers per 10,000 population in rural areas). Within the public sector, the distribution of health services and resources was unequal and strongly favored the urban clinics. Regression analysis revealed that rural clinics had lower availability of services and resources after adjusting for ownership and patient load, but the associations were not significant except for workforce availability (adjusted odds ratio [OR]: 0.82; 95% confidence interval [CI]: 0.71–0.96). Conclusions Targeted primary care expansion in rural areas could be an effective first step towards achieving universal health coverage, especially in countries with limited healthcare resources. Nonetheless, geographic expansion alone is inadequate to achieve effective coverage in a dichotomous primary care system, and the role of the private sector in primary care delivery should not be overlooked. PMID:28196113

  4. Chasm in primary care provision in a universal health system: Findings from a nationally representative survey of health facilities in Malaysia.

    PubMed

    Lim, Huy Ming; Sivasampu, Sheamini; Khoo, Ee Ming; Mohamad Noh, Kamaliah

    2017-01-01

    Malaysia has achieved universal health coverage since 1980s through the expansion of direct public provision, particularly in rural areas. However, no systematic examination of the rural-urban distribution of primary care services and resources has been conducted to date for policy impact evaluation. We conducted a national cross-sectional survey of 316 public and 597 private primary care clinics, selected through proportionate stratified random sampling, from June 2011 through February 2012. Using a questionnaire developed based on the World Health Organization toolkits on monitoring health systems strengthening, we examined the availability of primary care services/resources and the associations between service/resource availability and clinic ownership, locality, and patient load. Data were weighted for all analyses to account for the complex survey design and produce unbiased national estimates. Private primary care clinics and doctors outnumbered their public counterparts by factors of 5.6 and 3.9, respectively, but the private clinics were significantly less well-equipped with basic facilities and provided a more limited range of services. Per capita densities of primary care clinics and workforce were higher in urban areas (2.2 clinics and 15.1 providers per 10,000 population in urban areas versus 1.1 clinics and 11.7 providers per 10,000 population in rural areas). Within the public sector, the distribution of health services and resources was unequal and strongly favored the urban clinics. Regression analysis revealed that rural clinics had lower availability of services and resources after adjusting for ownership and patient load, but the associations were not significant except for workforce availability (adjusted odds ratio [OR]: 0.82; 95% confidence interval [CI]: 0.71-0.96). Targeted primary care expansion in rural areas could be an effective first step towards achieving universal health coverage, especially in countries with limited healthcare resources. Nonetheless, geographic expansion alone is inadequate to achieve effective coverage in a dichotomous primary care system, and the role of the private sector in primary care delivery should not be overlooked.

  5. Observational studies of patients in the emergency department: a comparison of 4 sampling methods.

    PubMed

    Valley, Morgan A; Heard, Kennon J; Ginde, Adit A; Lezotte, Dennis C; Lowenstein, Steven R

    2012-08-01

    We evaluate the ability of 4 sampling methods to generate representative samples of the emergency department (ED) population. We analyzed the electronic records of 21,662 consecutive patient visits at an urban, academic ED. From this population, we simulated different models of study recruitment in the ED by using 2 sample sizes (n=200 and n=400) and 4 sampling methods: true random, random 4-hour time blocks by exact sample size, random 4-hour time blocks by a predetermined number of blocks, and convenience or "business hours." For each method and sample size, we obtained 1,000 samples from the population. Using χ(2) tests, we measured the number of statistically significant differences between the sample and the population for 8 variables (age, sex, race/ethnicity, language, triage acuity, arrival mode, disposition, and payer source). Then, for each variable, method, and sample size, we compared the proportion of the 1,000 samples that differed from the overall ED population to the expected proportion (5%). Only the true random samples represented the population with respect to sex, race/ethnicity, triage acuity, mode of arrival, language, and payer source in at least 95% of the samples. Patient samples obtained using random 4-hour time blocks and business hours sampling systematically differed from the overall ED patient population for several important demographic and clinical variables. However, the magnitude of these differences was not large. Common sampling strategies selected for ED-based studies may affect parameter estimates for several representative population variables. However, the potential for bias for these variables appears small. Copyright © 2012. Published by Mosby, Inc.

  6. A Bayesian sequential design with adaptive randomization for 2-sided hypothesis test.

    PubMed

    Yu, Qingzhao; Zhu, Lin; Zhu, Han

    2017-11-01

    Bayesian sequential and adaptive randomization designs are gaining popularity in clinical trials thanks to their potentials to reduce the number of required participants and save resources. We propose a Bayesian sequential design with adaptive randomization rates so as to more efficiently attribute newly recruited patients to different treatment arms. In this paper, we consider 2-arm clinical trials. Patients are allocated to the 2 arms with a randomization rate to achieve minimum variance for the test statistic. Algorithms are presented to calculate the optimal randomization rate, critical values, and power for the proposed design. Sensitivity analysis is implemented to check the influence on design by changing the prior distributions. Simulation studies are applied to compare the proposed method and traditional methods in terms of power and actual sample sizes. Simulations show that, when total sample size is fixed, the proposed design can obtain greater power and/or cost smaller actual sample size than the traditional Bayesian sequential design. Finally, we apply the proposed method to a real data set and compare the results with the Bayesian sequential design without adaptive randomization in terms of sample sizes. The proposed method can further reduce required sample size. Copyright © 2017 John Wiley & Sons, Ltd.

  7. Breaking through the bandwidth barrier in distributed fiber vibration sensing by sub-Nyquist randomized sampling

    NASA Astrophysics Data System (ADS)

    Zhang, Jingdong; Zhu, Tao; Zheng, Hua; Kuang, Yang; Liu, Min; Huang, Wei

    2017-04-01

    The round trip time of the light pulse limits the maximum detectable frequency response range of vibration in phase-sensitive optical time domain reflectometry (φ-OTDR). We propose a method to break the frequency response range restriction of φ-OTDR system by modulating the light pulse interval randomly which enables a random sampling for every vibration point in a long sensing fiber. This sub-Nyquist randomized sampling method is suits for detecting sparse-wideband- frequency vibration signals. Up to MHz resonance vibration signal with over dozens of frequency components and 1.153MHz single frequency vibration signal are clearly identified for a sensing range of 9.6km with 10kHz maximum sampling rate.

  8. 78 FR 57033 - United States Standards for Condition of Food Containers

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-17

    ... containers during production. Stationary lot sampling is the process of randomly selecting sample units from.... * * * * * Stationary lot sampling. The process of randomly selecting sample units from a lot whose production has been... less than \\1/16\\-inch Stringy seal (excessive plastic threads showing at edge of seal 222 area...

  9. Health indicators: eliminating bias from convenience sampling estimators.

    PubMed

    Hedt, Bethany L; Pagano, Marcello

    2011-02-28

    Public health practitioners are often called upon to make inference about a health indicator for a population at large when the sole available information are data gathered from a convenience sample, such as data gathered on visitors to a clinic. These data may be of the highest quality and quite extensive, but the biases inherent in a convenience sample preclude the legitimate use of powerful inferential tools that are usually associated with a random sample. In general, we know nothing about those who do not visit the clinic beyond the fact that they do not visit the clinic. An alternative is to take a random sample of the population. However, we show that this solution would be wasteful if it excluded the use of available information. Hence, we present a simple annealing methodology that combines a relatively small, and presumably far less expensive, random sample with the convenience sample. This allows us to not only take advantage of powerful inferential tools, but also provides more accurate information than that available from just using data from the random sample alone. Copyright © 2011 John Wiley & Sons, Ltd.

  10. A Systematic Review of Surgical Randomized Controlled Trials: Part 2. Funding Source, Conflict of Interest, and Sample Size in Plastic Surgery.

    PubMed

    Voineskos, Sophocles H; Coroneos, Christopher J; Ziolkowski, Natalia I; Kaur, Manraj N; Banfield, Laura; Meade, Maureen O; Chung, Kevin C; Thoma, Achilleas; Bhandari, Mohit

    2016-02-01

    The authors examined industry support, conflict of interest, and sample size in plastic surgery randomized controlled trials that compared surgical interventions. They hypothesized that industry-funded trials demonstrate statistically significant outcomes more often, and randomized controlled trials with small sample sizes report statistically significant results more frequently. An electronic search identified randomized controlled trials published between 2000 and 2013. Independent reviewers assessed manuscripts and performed data extraction. Funding source, conflict of interest, primary outcome direction, and sample size were examined. Chi-squared and independent-samples t tests were used in the analysis. The search identified 173 randomized controlled trials, of which 100 (58 percent) did not acknowledge funding status. A relationship between funding source and trial outcome direction was not observed. Both funding status and conflict of interest reporting improved over time. Only 24 percent (six of 25) of industry-funded randomized controlled trials reported authors to have independent control of data and manuscript contents. The mean number of patients randomized was 73 per trial (median, 43, minimum, 3, maximum, 936). Small trials were not found to be positive more often than large trials (p = 0.87). Randomized controlled trials with small sample size were common; however, this provides great opportunity for the field to engage in further collaboration and produce larger, more definitive trials. Reporting of trial funding and conflict of interest is historically poor, but it greatly improved over the study period. Underreporting at author and journal levels remains a limitation when assessing the relationship between funding source and trial outcomes. Improved reporting and manuscript control should be goals that both authors and journals can actively achieve.

  11. Random phase detection in multidimensional NMR.

    PubMed

    Maciejewski, Mark W; Fenwick, Matthew; Schuyler, Adam D; Stern, Alan S; Gorbatyuk, Vitaliy; Hoch, Jeffrey C

    2011-10-04

    Despite advances in resolution accompanying the development of high-field superconducting magnets, biomolecular applications of NMR require multiple dimensions in order to resolve individual resonances, and the achievable resolution is typically limited by practical constraints on measuring time. In addition to the need for measuring long evolution times to obtain high resolution, the need to distinguish the sign of the frequency constrains the ability to shorten measuring times. Sign discrimination is typically accomplished by sampling the signal with two different receiver phases or by selecting a reference frequency outside the range of frequencies spanned by the signal and then sampling at a higher rate. In the parametrically sampled (indirect) time dimensions of multidimensional NMR experiments, either method imposes an additional factor of 2 sampling burden for each dimension. We demonstrate that by using a single detector phase at each time sample point, but randomly altering the phase for different points, the sign ambiguity that attends fixed single-phase detection is resolved. Random phase detection enables a reduction in experiment time by a factor of 2 for each indirect dimension, amounting to a factor of 8 for a four-dimensional experiment, albeit at the cost of introducing sampling artifacts. Alternatively, for fixed measuring time, random phase detection can be used to double resolution in each indirect dimension. Random phase detection is complementary to nonuniform sampling methods, and their combination offers the potential for additional benefits. In addition to applications in biomolecular NMR, random phase detection could be useful in magnetic resonance imaging and other signal processing contexts.

  12. High-speed imaging using CMOS image sensor with quasi pixel-wise exposure

    NASA Astrophysics Data System (ADS)

    Sonoda, T.; Nagahara, H.; Endo, K.; Sugiyama, Y.; Taniguchi, R.

    2017-02-01

    Several recent studies in compressive video sensing have realized scene capture beyond the fundamental trade-off limit between spatial resolution and temporal resolution using random space-time sampling. However, most of these studies showed results for higher frame rate video that were produced by simulation experiments or using an optically simulated random sampling camera, because there are currently no commercially available image sensors with random exposure or sampling capabilities. We fabricated a prototype complementary metal oxide semiconductor (CMOS) image sensor with quasi pixel-wise exposure timing that can realize nonuniform space-time sampling. The prototype sensor can reset exposures independently by columns and fix these amount of exposure by rows for each 8x8 pixel block. This CMOS sensor is not fully controllable via the pixels, and has line-dependent controls, but it offers flexibility when compared with regular CMOS or charge-coupled device sensors with global or rolling shutters. We propose a method to realize pseudo-random sampling for high-speed video acquisition that uses the flexibility of the CMOS sensor. We reconstruct the high-speed video sequence from the images produced by pseudo-random sampling using an over-complete dictionary.

  13. ADAPTIVE MATCHING IN RANDOMIZED TRIALS AND OBSERVATIONAL STUDIES

    PubMed Central

    van der Laan, Mark J.; Balzer, Laura B.; Petersen, Maya L.

    2014-01-01

    SUMMARY In many randomized and observational studies the allocation of treatment among a sample of n independent and identically distributed units is a function of the covariates of all sampled units. As a result, the treatment labels among the units are possibly dependent, complicating estimation and posing challenges for statistical inference. For example, cluster randomized trials frequently sample communities from some target population, construct matched pairs of communities from those included in the sample based on some metric of similarity in baseline community characteristics, and then randomly allocate a treatment and a control intervention within each matched pair. In this case, the observed data can neither be represented as the realization of n independent random variables, nor, contrary to current practice, as the realization of n/2 independent random variables (treating the matched pair as the independent sampling unit). In this paper we study estimation of the average causal effect of a treatment under experimental designs in which treatment allocation potentially depends on the pre-intervention covariates of all units included in the sample. We define efficient targeted minimum loss based estimators for this general design, present a theorem that establishes the desired asymptotic normality of these estimators and allows for asymptotically valid statistical inference, and discuss implementation of these estimators. We further investigate the relative asymptotic efficiency of this design compared with a design in which unit-specific treatment assignment depends only on the units’ covariates. Our findings have practical implications for the optimal design and analysis of pair matched cluster randomized trials, as well as for observational studies in which treatment decisions may depend on characteristics of the entire sample. PMID:25097298

  14. Adaptive Peer Sampling with Newscast

    NASA Astrophysics Data System (ADS)

    Tölgyesi, Norbert; Jelasity, Márk

    The peer sampling service is a middleware service that provides random samples from a large decentralized network to support gossip-based applications such as multicast, data aggregation and overlay topology management. Lightweight gossip-based implementations of the peer sampling service have been shown to provide good quality random sampling while also being extremely robust to many failure scenarios, including node churn and catastrophic failure. We identify two problems with these approaches. The first problem is related to message drop failures: if a node experiences a higher-than-average message drop rate then the probability of sampling this node in the network will decrease. The second problem is that the application layer at different nodes might request random samples at very different rates which can result in very poor random sampling especially at nodes with high request rates. We propose solutions for both problems. We focus on Newscast, a robust implementation of the peer sampling service. Our solution is based on simple extensions of the protocol and an adaptive self-control mechanism for its parameters, namely—without involving failure detectors—nodes passively monitor local protocol events using them as feedback for a local control loop for self-tuning the protocol parameters. The proposed solution is evaluated by simulation experiments.

  15. Final report : sampling plan for pavement condition ratings of secondary roads.

    DOT National Transportation Integrated Search

    1984-01-01

    The purpose of this project was to develop a random sampling plan for use in selecting segments of the secondary highway system for evaluation under the Department's PMS. The plan developed is described here. It is a simple, workable, random sampling...

  16. Generating Random Samples of a Given Size Using Social Security Numbers.

    ERIC Educational Resources Information Center

    Erickson, Richard C.; Brauchle, Paul E.

    1984-01-01

    The purposes of this article are (1) to present a method by which social security numbers may be used to draw cluster samples of a predetermined size and (2) to describe procedures used to validate this method of drawing random samples. (JOW)

  17. On Proportionate and Truthful International Alliance Contributions: An Analysis of IncentiveCompatible Cost Sharing Mechanisms to Burden Sharing

    DTIC Science & Technology

    2017-03-23

    Therefore, the mecha- nism induces a stable cost sharing scheme wherein a subset of colluding players will not all benefit . In a subset of colluding...goods are not divisible and are not excludable. Cost sharing mechanisms specific to public goods have been researched extensively in the literature...Jackson & Moulin [1992] consider the sharing of cost for an indivisible public project among many players, and their work was extended by Bag [1997] to

  18. Effect of Ultrasonic Frequency on Lactic Acid Fermentation Promotion by Ultrasonic Irradiation

    NASA Astrophysics Data System (ADS)

    Shimada, Tadayuki; Ohdaira, Etsuzo; Masuzawa, Nobuyoshi

    2004-05-01

    The authors have been researching the promotion of lactic acid fermentation by ultrasonic irradiation. In the past research, it was proven that ultrasonic irradiation is effective in the process of fermentation, and the production of yoghurt and kefir was promoted. In this study, the effect of the ultrasonic frequency in this fermentation process was examined. In the frequency range of this study, it was found that the action of fermentation promotion was exponentially proportionate to the irradiated ultrasonic frequency.

  19. Tensiometer for shallow or deep measurements including vadose zone and aquifers

    DOEpatents

    Faybishenko, B.

    1999-08-24

    A two cell tensiometer is described in which water level in the lower cell is maintained at a relatively constant height, and in equilibrium with the water pressure of materials that surround the tensiometer. An isolated volume of air in the lower cell changes pressure proportionately to the changing water pressure of the materials that surround the tensiometer. The air pressure is measured remotely. The tensiometer can be used in drying as well as wetting cycles above and below the water table. 8 figs.

  20. PAROTID FLUID CORTICOSTEROID RESPONSE IN NORMAL SUBJECTS DURING SINGLE-DOSE DEXAMETHASONE SUPPRESSION TESTS.

    DTIC Science & Technology

    Serum and parotid 17-OHCS measurements were carried out on 6 healthy young adult males during a control week and during a second week in which single...hours after dexamethasone dosage the serum steroid mean decreased by 84.6% and the decrease in parotid fluid concentration was 76.6%. The highly...significant suppression of the level of 17-OHCS in serum was proportionately reflected in the steroid response in parotid fluid. These results suggest that

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