32 CFR 1800.21 - Processing of requests for records.

Code of Federal Regulations, 2012 CFR

2012-07-01

... components reasonably believed to hold responsive records. (b) Database of “officially released information... database of “officially released information” which contains copies of documents released by NACIC. Searches of this database can be accomplished expeditiously. Moreover, requests that are specific and well...

32 CFR 1800.21 - Processing of requests for records.

Code of Federal Regulations, 2010 CFR

2010-07-01

... components reasonably believed to hold responsive records. (b) Database of “officially released information... database of “officially released information” which contains copies of documents released by NACIC. Searches of this database can be accomplished expeditiously. Moreover, requests that are specific and well...

43 CFR 11.41 - What data must the authorized official supply?

Code of Federal Regulations, 2011 CFR

2011-10-01

... authorized official is not aware of any reliable evidence that ice was absent from the site of the release, then he or she must turn on the ice modeling function. Otherwise, the authorized official must leave the ice modeling function off. (2) If the release occurred in the Great Lakes and the authorized...

43 CFR 11.41 - What data must the authorized official supply?

Code of Federal Regulations, 2012 CFR

2012-10-01

... authorized official is not aware of any reliable evidence that ice was absent from the site of the release, then he or she must turn on the ice modeling function. Otherwise, the authorized official must leave the ice modeling function off. (2) If the release occurred in the Great Lakes and the authorized...

43 CFR 11.41 - What data must the authorized official supply?

Code of Federal Regulations, 2013 CFR

2013-10-01

... authorized official is not aware of any reliable evidence that ice was absent from the site of the release, then he or she must turn on the ice modeling function. Otherwise, the authorized official must leave the ice modeling function off. (2) If the release occurred in the Great Lakes and the authorized...

43 CFR 11.41 - What data must the authorized official supply?

Code of Federal Regulations, 2014 CFR

2014-10-01

... authorized official is not aware of any reliable evidence that ice was absent from the site of the release, then he or she must turn on the ice modeling function. Otherwise, the authorized official must leave the ice modeling function off. (2) If the release occurred in the Great Lakes and the authorized...

43 CFR 11.41 - What data must the authorized official supply?

Code of Federal Regulations, 2010 CFR

2010-10-01

... authorized official is not aware of any reliable evidence that ice was absent from the site of the release, then he or she must turn on the ice modeling function. Otherwise, the authorized official must leave the ice modeling function off. (2) If the release occurred in the Great Lakes and the authorized...

32 CFR 1900.21 - Processing of requests for records.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Information Act Amendments of 1996. (b) Database of “officially released information.” As an alternative to extensive tasking and as an accommodation to many requesters, the Agency maintains a database of “officially released information” which contains copies of documents released by this Agency. Searches of this database...

Release parameters at the foul line and the official result in javelin throwing.

PubMed

Viitasalo, Jukka; Mononen, Harri; Norvapalo, Kare

2003-01-01

Range in javelin throwing is determined by the release parameters and aerodynamic factors. The current study was designed to investigate the effects of release speed, release angle and uncorrected angle of attack measured at the foul line on the official javelin throwing result. The data were collected in international competitions for 26 elite male and 15 elite female javelin throwers (total 248 throws). Multiple regression models were constructed to predict the range of throw for a) individual throwers, b) a group of throwers using the mean value for each thrower in the analysis, and c) all individual throws registered for each gender separately. The data collection was carried out using a computerised photocell gate that consists of two invisible infrared walls two metres apart, perpendicular to the throwing direction. Release speed was found to have the highest correlation with the official throwing result. The three release parameters accounted for 56% of the variance in the official result for the male and 51% for the female throwers. For individual male and female throwers, the variance explained by the model was between 46 and 87%. Among the individual male throwers an increase of 1 m.s-1 in the release speed from 29 to 30 m.s-1 was calculated to increase the official result between 2.12 to 6.14 m while among the female throwers the effect of increase from 24 to 25 m.s-1 in the release speed was from 2.25 to 3.68 m. The study emphasises the importance of investigating javelin throwing biomechanics on an individual thrower basis.

Evaluation of Protocol Uniformity Concerning Laparoscopic Cholecystectomy in The Netherlands

PubMed Central

Goossens, Richard H. M.; van Eijk, Daan J.; Lange, Johan F.

2008-01-01

Background Iatrogenic bile duct injury remains a current complication of laparoscopic cholecystectomy. One uniform and standardized protocol, based on the “critical view of safety” concept of Strasberg, should reduce the incidence of this complication. Furthermore, owing to the rapid development of minimally invasive surgery, technicians are becoming more frequently involved. To improve communication between the operating team and technicians, standardized actions should also be defined. The aim of this study was to compare existing protocols for laparoscopic cholecystectomy from various Dutch hospitals. Methods Fifteen Dutch hospitals were contacted for evaluation of their protocols for laparoscopic cholecystectomy. All evaluated protocols were divided into six steps and were compared accordingly. Results In total, 13 hospitals responded—5 academic hospitals, 5 teaching hospitals, 3 community hospitals—of which 10 protocols were usable for comparison. Concerning the trocar positions, only minor differences were found. The concept of “critical view of safety” was represented in just one protocol. Furthermore, the order of clipping and cutting the cystic artery and duct differed. Descriptions of instruments and apparatus were also inconsistent. Conclusions Present protocols differ too much to define a universal procedure among surgeons in The Netherlands. The authors propose one (inter)national standardized protocol, including standardized actions. This uniform standardized protocol has to be officially released and recommended by national scientific associations (e.g., the Dutch Society of Surgery) or international societies (e.g., European Association for Endoscopic Surgery and Society of American Gastrointestinal and Endoscopic Surgeons). The aim is to improve patient safety and professional communication, which are necessary for new developments. PMID:18224485

32 CFR 93.2 - Purpose and applicability.

Code of Federal Regulations, 2011 CFR

2011-07-01

... ACCEPTANCE OF SERVICE OF PROCESS; RELEASE OF OFFICIAL INFORMATION IN LITIGATION; AND TESTIMONY BY NSA... NSA). The procedures herein are also promulgated pursuant to the NSA's independent authority, under... procedures for service of process at NSA and for the release of official information in litigation by NSA...

32 CFR 93.2 - Purpose and applicability.

Code of Federal Regulations, 2012 CFR

2012-07-01

... ACCEPTANCE OF SERVICE OF PROCESS; RELEASE OF OFFICIAL INFORMATION IN LITIGATION; AND TESTIMONY BY NSA... NSA). The procedures herein are also promulgated pursuant to the NSA's independent authority, under... procedures for service of process at NSA and for the release of official information in litigation by NSA...

32 CFR 93.2 - Purpose and applicability.

Code of Federal Regulations, 2014 CFR

2014-07-01

... ACCEPTANCE OF SERVICE OF PROCESS; RELEASE OF OFFICIAL INFORMATION IN LITIGATION; AND TESTIMONY BY NSA... NSA). The procedures herein are also promulgated pursuant to the NSA's independent authority, under... procedures for service of process at NSA and for the release of official information in litigation by NSA...

32 CFR 93.2 - Purpose and applicability.

Code of Federal Regulations, 2013 CFR

2013-07-01

... ACCEPTANCE OF SERVICE OF PROCESS; RELEASE OF OFFICIAL INFORMATION IN LITIGATION; AND TESTIMONY BY NSA... NSA). The procedures herein are also promulgated pursuant to the NSA's independent authority, under... procedures for service of process at NSA and for the release of official information in litigation by NSA...

32 CFR 93.2 - Purpose and applicability.

Code of Federal Regulations, 2010 CFR

2010-07-01

... ACCEPTANCE OF SERVICE OF PROCESS; RELEASE OF OFFICIAL INFORMATION IN LITIGATION; AND TESTIMONY BY NSA... NSA). The procedures herein are also promulgated pursuant to the NSA's independent authority, under... procedures for service of process at NSA and for the release of official information in litigation by NSA...

32 CFR 811.3 - Official requests for visual information productions or materials.

Code of Federal Regulations, 2010 CFR

2010-07-01

... THE AIR FORCE SALES AND SERVICES RELEASE, DISSEMINATION, AND SALE OF VISUAL INFORMATION MATERIALS § 811.3 Official requests for visual information productions or materials. (a) Send official Air Force... 32 National Defense 6 2010-07-01 2010-07-01 false Official requests for visual information...

DDN (Defense Data Network) Protocol Handbook. Volume 1. DoD Military Standard Protocols

DTIC Science & Technology

1985-12-01

official Military Standard communication protocols in use on the DDN are included, as are several ARPANET (Advanced Research Projects Agency Network... research protocols which are currently in use, and some protocols currently undergoing review. Tutorial information and auxiliary documents are also...compatible with DoD needs, by researchers wishing to improve the protocols, and by impleroentors of local area networks (LANs) wishing their

Validation of quantitative and qualitative methods for detecting allergenic ingredients in processed foods in Japan.

PubMed

Sakai, Shinobu; Adachi, Reiko; Akiyama, Hiroshi; Teshima, Reiko

2013-06-19

A labeling system for food allergenic ingredients was established in Japan in April 2002. To monitor the labeling, the Japanese government announced official methods for detecting allergens in processed foods in November 2002. The official methods consist of quantitative screening tests using enzyme-linked immunosorbent assays (ELISAs) and qualitative confirmation tests using Western blotting or polymerase chain reactions (PCR). In addition, the Japanese government designated 10 μg protein/g food (the corresponding allergenic ingredient soluble protein weight/food weight), determined by ELISA, as the labeling threshold. To standardize the official methods, the criteria for the validation protocol were described in the official guidelines. This paper, which was presented at the Advances in Food Allergen Detection Symposium, ACS National Meeting and Expo, San Diego, CA, Spring 2012, describes the validation protocol outlined in the official Japanese guidelines, the results of interlaboratory studies for the quantitative detection method (ELISA for crustacean proteins) and the qualitative detection method (PCR for shrimp and crab DNAs), and the reliability of the detection methods.

Prescriptions for uncomplicated malaria treatment among pregnant women in the Brazilian Amazon: evidences from the Mafalda Project.

PubMed

Luz, Tatiana Chama Borges; Miranda, Elaine Silva; Freitas, Letícia Figueira; Osório-de-Castro, Claudia Garcia Serpa

2013-06-01

To evaluate antimalarial prescriptions according to quality indicators and to describe adverse events reports among pregnant women with uncomplicated malaria. Descriptive study of medical files of pregnant women 15 years and older, residents in high-risk municipalities in the Brazilian Amazon. Antimalarial medicines were characterized by frequency of prescription, type of plasmodium and health care facilities where prescribing took place, and by possible adverse events. Variables were compared by Pearson's chi-square. A total of 262 medical files were evaluated. Most patients were diagnosed for Plasmodium vivax 71,2%. Chloroquine was the commonest prescribed antimalarial (65.6%). Of P. vivax prescriptions, 9.0%, and 16.2% of P. falciparum prescriptions presented antimalarials not recommended in the official protocol. Prescriptions for P. falciparum , in significantly higher proportion, did not adhere to the official protocol in regard to type of antimalarial and dose/duration of treatment (p = 0,001). They also lacked information on dose and dosing interval (p = 0,004). There were no significant differences among reference centers and basic health care units in respect to the prescribed antimalarials, to prescriptions containing antimalarials not recommended in the official protocol or in respect to lack of dosing information. Chloroquine was the antimalarial most related to the occurrence of adverse events. THE findings indicate that there are flaws in antimalarial prescribing for pregnant women, especially in respect to their adequacy to the official protocol.

43 CFR 11.36 - May the authorized official use both type A and type B procedures for the same release?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false May the authorized official use both type A and type B procedures for the same release? 11.36 Section 11.36 Public Lands: Interior Office of the Secretary of the Interior NATURAL RESOURCE DAMAGE ASSESSMENTS Assessment Plan Phase § 11.36 May...

43 CFR 11.36 - May the authorized official use both type A and type B procedures for the same release?

Code of Federal Regulations, 2011 CFR

2011-10-01

... 43 Public Lands: Interior 1 2011-10-01 2011-10-01 false May the authorized official use both type A and type B procedures for the same release? 11.36 Section 11.36 Public Lands: Interior Office of the Secretary of the Interior NATURAL RESOURCE DAMAGE ASSESSMENTS Assessment Plan Phase § 11.36 May...

32 CFR 516.48 - Official information.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 3 2012-07-01 2009-07-01 true Official information. 516.48 Section 516.48... PUBLIC RELATIONS LITIGATION Release of Information and Appearance of Witnesses Scope Da Personnel As Witnesses in Private Litigation § 516.48 Official information. (a) In instances involving § 516.47(a)(1...

32 CFR 516.48 - Official information.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 3 2014-07-01 2014-07-01 false Official information. 516.48 Section 516.48... PUBLIC RELATIONS LITIGATION Release of Information and Appearance of Witnesses Scope Da Personnel As Witnesses in Private Litigation § 516.48 Official information. (a) In instances involving § 516.47(a)(1...

22 CFR 213.28 - Execution of releases.

Code of Federal Regulations, 2010 CFR

2010-04-01

... and execute a release on behalf of the United States. In the event a mutual release is not executed... all claims and causes of action against USAID and its officials related to the transaction giving rise...

22 CFR 213.28 - Execution of releases.

Code of Federal Regulations, 2011 CFR

2011-04-01

... and execute a release on behalf of the United States. In the event a mutual release is not executed... all claims and causes of action against USAID and its officials related to the transaction giving rise...

Protocol for Addressing Induced Seismicity Associated with Enhanced Geothermal Systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Majer, Ernie; Nelson, James; Robertson-Tait, Ann

2012-01-01

This Protocol is a living guidance document for geothermal developers, public officials, regulators and the general public that provides a set of general guidelines detailing useful steps to evaluate and manage the effects of induced seismicity related to EGS projects.

22 CFR 2.5 - Records.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Records. 2.5 Section 2.5 Foreign Relations DEPARTMENT OF STATE GENERAL PROTECTION OF FOREIGN DIGNITARIES AND OTHER OFFICIAL PERSONNEL § 2.5 Records. The Chief of Protocol shall maintain as a part of the official files of the Department of State a cumulative...

22 CFR 2.5 - Records.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Records. 2.5 Section 2.5 Foreign Relations DEPARTMENT OF STATE GENERAL PROTECTION OF FOREIGN DIGNITARIES AND OTHER OFFICIAL PERSONNEL § 2.5 Records. The Chief of Protocol shall maintain as a part of the official files of the Department of State a cumulative...

22 CFR 2.5 - Records.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Records. 2.5 Section 2.5 Foreign Relations DEPARTMENT OF STATE GENERAL PROTECTION OF FOREIGN DIGNITARIES AND OTHER OFFICIAL PERSONNEL § 2.5 Records. The Chief of Protocol shall maintain as a part of the official files of the Department of State a cumulative...

22 CFR 2.5 - Records.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Records. 2.5 Section 2.5 Foreign Relations DEPARTMENT OF STATE GENERAL PROTECTION OF FOREIGN DIGNITARIES AND OTHER OFFICIAL PERSONNEL § 2.5 Records. The Chief of Protocol shall maintain as a part of the official files of the Department of State a cumulative...

7 CFR 1.15 - General provisions respecting release of records.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 1 2013-01-01 2013-01-01 false General provisions respecting release of records. 1.15 Section 1.15 Agriculture Office of the Secretary of Agriculture ADMINISTRATIVE REGULATIONS Official Records § 1.15 General provisions respecting release of records. (a) When releasing documents, agencies...

18 CFR 1301.52 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... by TVA Employees, Production of Official Records, and Disclosure of Official Information in Legal... testimony or production of documents or other material, including an affidavit, deposition, interrogatory... legislative body), for the production, disclosure, or release of TVA records or information or for the...

Development of reagents for immunoassay of Phytophthora ramorum in nursery water samples

Treesearch

Douglas G. Luster; Timothy Widmer; Michael McMahon; C. André Lévesque

2017-01-01

Current regulations under the August 6, 2014 USDA APHIS Official Regulatory Protocol (Confirmed Nursery Protocol: Version 8.2) for Nurseries Containing Plants Infected with Phytophthora ramorum mandates the sampling of water in affected nurseries to demonstrate they are free of P. ramorum. Currently, detection of

Rapid calculation of genomic evaluations for new animals

USDA-ARS?s Scientific Manuscript database

A method was developed to calculate preliminary genomic evaluations daily or weekly before the release of official monthly evaluations by processing only newly genotyped animals using estimates of SNP effects from the previous official evaluation. To minimize computing time, reliabilities and genomi...

5 CFR 295.103 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... RELATING TO OFFICIAL INFORMATION AND PRODUCTION OF OFFICIAL RECORDS IN LEGAL PROCEEDINGS General Provisions... competent authority, for the production, disclosure, or release of records or for the appearance and... whatever method, for the production of records and information or for testimony which has not been ordered...

7 CFR 1.19 - Exemptions and discretionary release.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 1 2013-01-01 2013-01-01 false Exemptions and discretionary release. 1.19 Section 1.19 Agriculture Office of the Secretary of Agriculture ADMINISTRATIVE REGULATIONS Official Records § 1.19 Exemptions and discretionary release. (a) All agency records, except those specifically exempted...

Performance of Male Psychopaths Following Conditional Release from Prison.

ERIC Educational Resources Information Center

Hart, Stephen D.; And Others

1988-01-01

Administered Psychopathy Checklist (PCL) to criminals being released from prison on parole or mandatory supervision, then examined official parole supervision files for postrelease behavior. Violation of release conditions, suspensions, and presentation of supervisory problems were directly proportional, and the probability of subjects remaining…

Semiannual Report to the Congress: April 1, 2013 to September 30, 2013

DTIC Science & Technology

2013-09-30

company owned by a family member and used proprietary information in communications with senior DoD officials. The senior official left government...of the intelligence community , reviews of reprisal and senior official allegations and a review of the release of DoD information to the media...regardless of their location. Attendees gathered as a hotline community , shared relevant information , and discussed collective best practices and

42 CFR 93.206 - Debarring official.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false Debarring official. 93.206 Section 93.206 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH...

42 CFR 93.206 - Debarring official.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 42 Public Health 1 2011-10-01 2011-10-01 false Debarring official. 93.206 Section 93.206 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH...

TransGuide officially launches July 26 with VIP visit

DOT National Transportation Integrated Search

1995-07-03

In this press release issued from San Antonio, Texas, TransGuide, San Antonio's smart highway system will officially go on-line on Thursday, July 26, 1995, during a ceremony with U.S. Secretary of Transportation, : Federico F. Pena. This one-of-a-kin...

28 CFR 0.103 - Release of information.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Enforcement Administration § 0.103 Release of information. (a) The Administrator of DEA is authorized— (1) To release information obtained by DEA and DEA investigative reports to Federal, State, and local officials... by DEA and DEA investigative reports to Federal, State, and local prosecutors, and State licensing...

28 CFR 0.103 - Release of information.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Enforcement Administration § 0.103 Release of information. (a) The Administrator of DEA is authorized— (1) To release information obtained by DEA and DEA investigative reports to Federal, State, and local officials... by DEA and DEA investigative reports to Federal, State, and local prosecutors, and State licensing...

10 CFR 1707.101 - Scope and purpose.

Code of Federal Regulations, 2013 CFR

2013-01-01

... DEFENSE NUCLEAR FACILITIES SAFETY BOARD TESTIMONY BY DNFSB EMPLOYEES AND PRODUCTION OF OFFICIAL RECORDS IN... procedures you must follow when you submit a demand or request to an employee of the Defense Nuclear... you request the release or disclosure of official records and information. (b) The Defense Nuclear...

10 CFR 1707.101 - Scope and purpose.

Code of Federal Regulations, 2011 CFR

2011-01-01

... DEFENSE NUCLEAR FACILITIES SAFETY BOARD TESTIMONY BY DNFSB EMPLOYEES AND PRODUCTION OF OFFICIAL RECORDS IN... procedures you must follow when you submit a demand or request to an employee of the Defense Nuclear... you request the release or disclosure of official records and information. (b) The Defense Nuclear...

10 CFR 1707.101 - Scope and purpose.

Code of Federal Regulations, 2012 CFR

2012-01-01

... DEFENSE NUCLEAR FACILITIES SAFETY BOARD TESTIMONY BY DNFSB EMPLOYEES AND PRODUCTION OF OFFICIAL RECORDS IN... procedures you must follow when you submit a demand or request to an employee of the Defense Nuclear... you request the release or disclosure of official records and information. (b) The Defense Nuclear...

10 CFR 1707.101 - Scope and purpose.

Code of Federal Regulations, 2010 CFR

2010-01-01

... DEFENSE NUCLEAR FACILITIES SAFETY BOARD TESTIMONY BY DNFSB EMPLOYEES AND PRODUCTION OF OFFICIAL RECORDS IN... procedures you must follow when you submit a demand or request to an employee of the Defense Nuclear... you request the release or disclosure of official records and information. (b) The Defense Nuclear...

10 CFR 1707.101 - Scope and purpose.

Code of Federal Regulations, 2014 CFR

2014-01-01

... DEFENSE NUCLEAR FACILITIES SAFETY BOARD TESTIMONY BY DNFSB EMPLOYEES AND PRODUCTION OF OFFICIAL RECORDS IN... procedures you must follow when you submit a demand or request to an employee of the Defense Nuclear... you request the release or disclosure of official records and information. (b) The Defense Nuclear...

40 CFR 1400.11 - Limitation on dissemination to State and local government officials.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Limitation on dissemination to State and local government officials. 1400.11 Section 1400.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY AND DEPARTMENT OF JUSTICE ACCIDENTAL RELEASE PREVENTION REQUIREMENTS; RISK MANAGEMENT...

32 CFR 93.7 - Responsibilities.

Code of Federal Regulations, 2012 CFR

2012-07-01

... ACCEPTANCE OF SERVICE OF PROCESS; RELEASE OF OFFICIAL INFORMATION IN LITIGATION; AND TESTIMONY BY NSA... overseeing NSA compliance with § 93.1(a) and this part 93, and for consulting with DoJ when appropriate. In response to a litigation demand requesting official information or the testimony of NSA personnel as...

32 CFR 93.7 - Responsibilities.

Code of Federal Regulations, 2010 CFR

2010-07-01

... ACCEPTANCE OF SERVICE OF PROCESS; RELEASE OF OFFICIAL INFORMATION IN LITIGATION; AND TESTIMONY BY NSA... overseeing NSA compliance with § 93.1(a) and this part 93, and for consulting with DoJ when appropriate. In response to a litigation demand requesting official information or the testimony of NSA personnel as...

32 CFR 93.7 - Responsibilities.

Code of Federal Regulations, 2011 CFR

2011-07-01

... ACCEPTANCE OF SERVICE OF PROCESS; RELEASE OF OFFICIAL INFORMATION IN LITIGATION; AND TESTIMONY BY NSA... overseeing NSA compliance with § 93.1(a) and this part 93, and for consulting with DoJ when appropriate. In response to a litigation demand requesting official information or the testimony of NSA personnel as...

32 CFR 93.7 - Responsibilities.

Code of Federal Regulations, 2013 CFR

2013-07-01

... ACCEPTANCE OF SERVICE OF PROCESS; RELEASE OF OFFICIAL INFORMATION IN LITIGATION; AND TESTIMONY BY NSA... overseeing NSA compliance with § 93.1(a) and this part 93, and for consulting with DoJ when appropriate. In response to a litigation demand requesting official information or the testimony of NSA personnel as...

32 CFR 93.7 - Responsibilities.

Code of Federal Regulations, 2014 CFR

2014-07-01

... ACCEPTANCE OF SERVICE OF PROCESS; RELEASE OF OFFICIAL INFORMATION IN LITIGATION; AND TESTIMONY BY NSA... overseeing NSA compliance with § 93.1(a) and this part 93, and for consulting with DoJ when appropriate. In response to a litigation demand requesting official information or the testimony of NSA personnel as...

Mobility Demonstrator

DTIC Science & Technology

2013-08-22

charging system for increased power density. Compact two-stage turbocharger systems. UNCLASSIFIED: Distribution Statement A. Approved for public...advanced waste heat recovery, solid state cooling, turbocharging /turbocompounding UNCLASSIFIED: Distribution Statement A. Approved for public release... Turbocharging For Official Use Only For Official Use Only 77 •System – develop components capable of handling multiple roles within thermal

9 CFR 590.415 - Use of other official identification.

Code of Federal Regulations, 2010 CFR

2010-01-01

... which are permitted to bear the official inspection mark shown in § 590.412, except for pasteurization... not be released into consuming channels until they have been subjected to pasteurization, heat... with the identification set forth in Figure 3 of this section. After pasteurization or treatment, the...

10 CFR 1015.307 - Mutual releases of the debtor and the Government.

Code of Federal Regulations, 2010 CFR

2010-01-01

... STATES Standards for the Compromise of Claims § 1015.307 Mutual releases of the debtor and the Government... action against the Government and its officials related to the transaction giving rise to the compromised...

10 CFR 1015.307 - Mutual releases of the debtor and the Government.

Code of Federal Regulations, 2011 CFR

2011-01-01

... STATES Standards for the Compromise of Claims § 1015.307 Mutual releases of the debtor and the Government... action against the Government and its officials related to the transaction giving rise to the compromised...

Determination of Nitrogen, Phosphorus, and Potassium Release Rates of Slow- and Controlled-Release Fertilizers: Single-Laboratory Validation, First Action 2015.15.

PubMed

Thiex, Nancy

2016-01-01

A previously validated method for the determination of nitrogen release patterns of slow- and controlled-release fertilizers (SRFs and CRFs, respectively) was submitted to the Expert Review Panel (ERP) for Fertilizers for consideration of First Action Official Method(SM) status. The ERP evaluated the single-laboratory validation results and recommended the method for First Action Official Method status and provided recommendations for achieving Final Action. The 180 day soil incubation-column leaching technique was demonstrated to be a robust and reliable method for characterizing N release patterns from SRFs and CRFs. The method was reproducible, and the results were only slightly affected by variations in environmental factors such as microbial activity, soil moisture, temperature, and texture. The release of P and K were also studied, but at fewer replications than for N. Optimization experiments on the accelerated 74 h extraction method indicated that temperature was the only factor found to substantially influence nutrient-release rates from the materials studied, and an optimized extraction profile was established as follows: 2 h at 25°C, 2 h at 50°C, 20 h at 55°C, and 50 h at 60°C.

In Brief: Kyoto Protocol moves forward

NASA Astrophysics Data System (ADS)

Showstack, Randy

2004-10-01

The Russian cabinet's 30 September endorsement of the Kyoto Protocol to the United Nations Framework Convention on Climate Change (UNFCCC) likely clears the way for the treaty's ratification by that country's parliament and for its entry into force. The protocol enters into force when not less than 55 Parties to the Convention, including industrialized countries (so called ``Annex I Parties'') which accounted in total for at least 55 % of the total carbon dioxide emissions for 1990 from that group, officially have agreed to the treaty.

43 CFR 11.91 - How does the authorized official seek recovery of the assessed damages from the potentially...

Code of Federal Regulations, 2010 CFR

2010-10-01

...: Interior Office of the Secretary of the Interior NATURAL RESOURCE DAMAGE ASSESSMENTS Post-Assessment Phase... performed by a Federal or State official in accordance with this part, the natural resource damage... location and description of the injured resource, the type of discharge or release determined to have...

43 CFR 11.91 - How does the authorized official seek recovery of the assessed damages from the potentially...

Code of Federal Regulations, 2011 CFR

2011-10-01

...: Interior Office of the Secretary of the Interior NATURAL RESOURCE DAMAGE ASSESSMENTS Post-Assessment Phase... performed by a Federal or State official in accordance with this part, the natural resource damage... location and description of the injured resource, the type of discharge or release determined to have...

Determining drug release rates of hydrophobic compounds from nanocarriers

PubMed Central

D’Addio, Suzanne M.; Bukari, Abdallah A.; Dawoud, Mohammed; Bunjes, Heike; Rinaldi, Carlos; Prud’homme, Robert K.

2016-01-01

Obtaining meaningful drug release profiles for drug formulations is essential prior to in vivo testing and for ensuring consistent quality. The release kinetics of hydrophobic drugs from nanocarriers (NCs) are not well understood because the standard protocols for maintaining sink conditions and sampling are not valid owing to mass transfer and solubility limitations. In this work, a new in vitroassay protocol based on ‘lipid sinks’ and magnetic separation produces release conditions that mimic the concentrations of lipid membranes and lipoproteins in vivo, facilitates separation, and thus allows determination of intrinsic release rates of drugs from NCs. The assay protocol is validated by (i) determining the magnetic separation efficiency, (ii) demonstrating that sink condition requirements are met, and (iii) accounting for drug by completing a mass balance. NCs of itraconazole and cyclosporine A (CsA) were prepared and the drug release profiles were determined. This release protocol has been used to compare the drug release from a polymer stabilized NC of CsA to a solid drug NP of CsA alone. These data have led to the finding that stabilizing block copolymer layers have a retarding effect on drug release from NCs, reducing the rate of CsA release fourfold compared with the nanoparticle without a polymer coating. This article is part of the themed issue ‘Soft interfacial materials: from fundamentals to formulation’. PMID:27298440

Determining drug release rates of hydrophobic compounds from nanocarriers.

PubMed

D'Addio, Suzanne M; Bukari, Abdallah A; Dawoud, Mohammed; Bunjes, Heike; Rinaldi, Carlos; Prud'homme, Robert K

2016-07-28

Obtaining meaningful drug release profiles for drug formulations is essential prior to in vivo testing and for ensuring consistent quality. The release kinetics of hydrophobic drugs from nanocarriers (NCs) are not well understood because the standard protocols for maintaining sink conditions and sampling are not valid owing to mass transfer and solubility limitations. In this work, a new in vitroassay protocol based on 'lipid sinks' and magnetic separation produces release conditions that mimic the concentrations of lipid membranes and lipoproteins in vivo, facilitates separation, and thus allows determination of intrinsic release rates of drugs from NCs. The assay protocol is validated by (i) determining the magnetic separation efficiency, (ii) demonstrating that sink condition requirements are met, and (iii) accounting for drug by completing a mass balance. NCs of itraconazole and cyclosporine A (CsA) were prepared and the drug release profiles were determined. This release protocol has been used to compare the drug release from a polymer stabilized NC of CsA to a solid drug NP of CsA alone. These data have led to the finding that stabilizing block copolymer layers have a retarding effect on drug release from NCs, reducing the rate of CsA release fourfold compared with the nanoparticle without a polymer coating.This article is part of the themed issue 'Soft interfacial materials: from fundamentals to formulation'. © 2016 The Author(s).

An extremely compensatible cigarette by design: documentary evidence on industry awareness and reactions to the Barclay filter design cheating the tar testing system.

PubMed

Kozlowski, L T; Dreschel, N A; Stellman, S D; Wilkenfeld, J; Weiss, E B; Goldberg, M E

2005-02-01

The Barclay cigarette (Brown & Williamson) was introduced in 1980 in the USA in the most expensive launch in history. In the USA and around the world, Barclay was later determined to have a grooved filter design that was compromised by human smokers in the normal act of smoking, but that was measured as ultra-low tar using the standard tar testing protocol. To evaluate whether Brown & Williamson knew of the compensatability of Barclay during the design process and before it was released; to evaluate initial responses of competing tobacco companies to Barclay, before complaints were made to the Federal Trade Commission in 1981. Internet databases of industry documents (Tobacco Documents Online, Legacy Tobacco Documents Library, Brown & Williamson Litigation discovery website, Guildford and major company websites) were searched using key words, key dates, and targeted searches. Documents related specifically to the development, evaluation and release of the Barclay cigarette and related to the responses by competing tobacco companies were examined. Documents indicate the manufacturer was aware of Barclay design problems and was planning, before release, to respond to criticism. Competing companies quickly detected the filter groove stratagem and considered developing their own similar filter, but eventually backed off. The design problems with Barclay were readily understood by cigarette manufacturers, including the maker of Barclay, before official governmental evaluations occurred. Testing involving measured exposures to human smokers may in the end be crucial to identifying problems with novel cigarette designs.

[Protocol for the treatment of severe acute pancreatitis with necrosis].

PubMed

Barreda, Luis; Targarona, Javier; Rodriguez, César

2005-01-01

The Severe Acute Pancreatic Unit of Edgardo Rebagliati Martins National Hospital was officially created in the year 2000. Up to date, we have cared for more than 195 patients with Pancreatic Necrosis. All of them have been treated under a management protocol presented by us. This has helped us to standardize treatment and also to compare results with work groups around the world. This Protocol comes from our own experience and that of our colleagues abroad with a wide knowledge in this kind of pathology abroad, with whom we maintain close ties.

75 FR 79370 - Official Release of the MOVES2010a and EMFAC2007 Motor Vehicle Emissions Models for...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-20

...: This Notice announces the availability of two new EPA guidance documents for: completing quantitative... of the MOVES model (MOVES2010a) for official use for quantitative CO, PM 2.5, and PM 10 hot-spot... emissions model is required to be used in quantitative CO and PM hot-spot analyses for project-level...

13 CFR 123.504 - How do you apply for a Military Reservist EIDL?

Code of Federal Regulations, 2011 CFR

2011-01-01

... Disaster Area Office) including: (a) A copy of the essential employee's official call-up orders for active duty showing the date of call-up, and, if known, the date of release from active duty. For an essential employee who expects to be called up and who has not received official call-up orders, the application...

32 CFR Appendix C to Part 516 - Department of Defense Directive 5405.2, Release of Official Information in Litigation and...

Code of Federal Regulations, 2013 CFR

2013-07-01

... Defense. 3. Litigation. All pretrial, trial, and post-trial stages of all existing or reasonably... Department of Justice, as required; and taking final action on such requests and demands. 2. Factors To... paragraph F.1., DoD officials should consider the following types of factors: a. Whether the request or...

32 CFR Appendix C to Part 516 - Department of Defense Directive 5405.2, Release of Official Information in Litigation and...

Code of Federal Regulations, 2011 CFR

2011-07-01

... Defense. 3. Litigation. All pretrial, trial, and post-trial stages of all existing or reasonably... Department of Justice, as required; and taking final action on such requests and demands. 2. Factors To... paragraph F.1., DoD officials should consider the following types of factors: a. Whether the request or...

32 CFR Appendix C to Part 516 - Department of Defense Directive 5405.2, Release of Official Information in Litigation and...

Code of Federal Regulations, 2014 CFR

2014-07-01

... Defense. 3. Litigation. All pretrial, trial, and post-trial stages of all existing or reasonably... Department of Justice, as required; and taking final action on such requests and demands. 2. Factors To... paragraph F.1., DoD officials should consider the following types of factors: a. Whether the request or...

32 CFR Appendix C to Part 516 - Department of Defense Directive 5405.2, Release of Official Information in Litigation and...

Code of Federal Regulations, 2012 CFR

2012-07-01

... Defense. 3. Litigation. All pretrial, trial, and post-trial stages of all existing or reasonably... Department of Justice, as required; and taking final action on such requests and demands. 2. Factors To... paragraph F.1., DoD officials should consider the following types of factors: a. Whether the request or...

32 CFR Appendix C to Part 516 - Department of Defense Directive 5405.2, Release of Official Information in Litigation and...

Code of Federal Regulations, 2010 CFR

2010-07-01

... Defense. 3. Litigation. All pretrial, trial, and post-trial stages of all existing or reasonably... Department of Justice, as required; and taking final action on such requests and demands. 2. Factors To... paragraph F.1., DoD officials should consider the following types of factors: a. Whether the request or...

Assuring bridge safety and serviceability in Europe

DOT National Transportation Integrated Search

2010-08-01

U.S. engineers need advanced tools and protocols to better assess and assure safety and serviceability of bridges. The Federal Highway Administration, American Association of State Highway and Transportation Officials, and National Cooperative Highwa...

[Batch release of immunoglobulin and monoclonal antibody products].

PubMed

Gross, S

2014-10-01

The Paul-Ehrlich Institute (PEI) is an independent institution of the Federal Republic of Germany responsible for performing official experimental batch testing of sera. The institute decides about the release of each batch and performs experimental research in the field. The experimental quality control ensures the potency of the product and also the absence of harmful impurities. For release of an immunoglobulin batch the marketing authorization holder has to submit the documentation of the manufacture and the results of quality control measures together with samples of the batch to the PEI. Experimental testing is performed according to the approved specifications regarding the efficacy and safety. Since implementation of the 15th German drug law amendment, the source of antibody is not defined anymore. According to § 32 German drug law, all batches of sera need to be released by an official control laboratory. Sera are medicinal products, which contain antibodies, antibody fragments or fusion proteins with a functional antibody portion. Therefore, all batches of monoclonal antibodies and derivatives must also be released by the PEI and the marketing authorization holder has to submit a batch release application. Under certain circumstances a waiver for certain products can be issued with regard to batch release. The conditions for such a waiver apply to the majority of monoclonal antibodies.

Template-based protein structure modeling using the RaptorX web server.

PubMed

Källberg, Morten; Wang, Haipeng; Wang, Sheng; Peng, Jian; Wang, Zhiyong; Lu, Hui; Xu, Jinbo

2012-07-19

A key challenge of modern biology is to uncover the functional role of the protein entities that compose cellular proteomes. To this end, the availability of reliable three-dimensional atomic models of proteins is often crucial. This protocol presents a community-wide web-based method using RaptorX (http://raptorx.uchicago.edu/) for protein secondary structure prediction, template-based tertiary structure modeling, alignment quality assessment and sophisticated probabilistic alignment sampling. RaptorX distinguishes itself from other servers by the quality of the alignment between a target sequence and one or multiple distantly related template proteins (especially those with sparse sequence profiles) and by a novel nonlinear scoring function and a probabilistic-consistency algorithm. Consequently, RaptorX delivers high-quality structural models for many targets with only remote templates. At present, it takes RaptorX ~35 min to finish processing a sequence of 200 amino acids. Since its official release in August 2011, RaptorX has processed ~6,000 sequences submitted by ~1,600 users from around the world.

Template-based protein structure modeling using the RaptorX web server

PubMed Central

Källberg, Morten; Wang, Haipeng; Wang, Sheng; Peng, Jian; Wang, Zhiyong; Lu, Hui; Xu, Jinbo

2016-01-01

A key challenge of modern biology is to uncover the functional role of the protein entities that compose cellular proteomes. To this end, the availability of reliable three-dimensional atomic models of proteins is often crucial. This protocol presents a community-wide web-based method using RaptorX (http://raptorx.uchicago.edu/) for protein secondary structure prediction, template-based tertiary structure modeling, alignment quality assessment and sophisticated probabilistic alignment sampling. RaptorX distinguishes itself from other servers by the quality of the alignment between a target sequence and one or multiple distantly related template proteins (especially those with sparse sequence profiles) and by a novel nonlinear scoring function and a probabilistic-consistency algorithm. Consequently, RaptorX delivers high-quality structural models for many targets with only remote templates. At present, it takes RaptorX ~35 min to finish processing a sequence of 200 amino acids. Since its official release in August 2011, RaptorX has processed ~6,000 sequences submitted by ~1,600 users from around the world. PMID:22814390

Campus Police/Media Relations.

ERIC Educational Resources Information Center

Mullendore, Philip

California state statutes and a series of court cases have required campus security and police departments to release information about incidents occurring on campus to the media and the general public. Despite the law and case decisions, recent studies reveal campus police and security officials are still reluctant to release information to the…

10 CFR 1707.208 - Restrictions that apply to released records.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Restrictions that apply to released records. 1707.208 Section 1707.208 Energy DEFENSE NUCLEAR FACILITIES SAFETY BOARD TESTIMONY BY DNFSB EMPLOYEES AND PRODUCTION OF OFFICIAL RECORDS IN LEGAL PROCEEDINGS Requests for Testimony and Production of Documents § 1707...

10 CFR 1707.208 - Restrictions that apply to released records.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Restrictions that apply to released records. 1707.208 Section 1707.208 Energy DEFENSE NUCLEAR FACILITIES SAFETY BOARD TESTIMONY BY DNFSB EMPLOYEES AND PRODUCTION OF OFFICIAL RECORDS IN LEGAL PROCEEDINGS Requests for Testimony and Production of Documents § 1707...

10 CFR 1707.208 - Restrictions that apply to released records.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Restrictions that apply to released records. 1707.208 Section 1707.208 Energy DEFENSE NUCLEAR FACILITIES SAFETY BOARD TESTIMONY BY DNFSB EMPLOYEES AND PRODUCTION OF OFFICIAL RECORDS IN LEGAL PROCEEDINGS Requests for Testimony and Production of Documents § 1707...

10 CFR 1707.208 - Restrictions that apply to released records.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Restrictions that apply to released records. 1707.208 Section 1707.208 Energy DEFENSE NUCLEAR FACILITIES SAFETY BOARD TESTIMONY BY DNFSB EMPLOYEES AND PRODUCTION OF OFFICIAL RECORDS IN LEGAL PROCEEDINGS Requests for Testimony and Production of Documents § 1707...

10 CFR 1707.208 - Restrictions that apply to released records.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Restrictions that apply to released records. 1707.208 Section 1707.208 Energy DEFENSE NUCLEAR FACILITIES SAFETY BOARD TESTIMONY BY DNFSB EMPLOYEES AND PRODUCTION OF OFFICIAL RECORDS IN LEGAL PROCEEDINGS Requests for Testimony and Production of Documents § 1707...

Investigation of "Skyscraper's" Feat

ERIC Educational Resources Information Center

Efthimiou, Costas

2018-01-01

"Skyscraper" is a Hollywood action film ("Skyscraper" official film site: www.skyscrapermovie.com) directed and written by Thurber scheduled to be released on 13 July 2018. We present an analysis of the feat shown in the recently released teaser poster and trailer of the film. Although the feat appears to be unrealistic at…

45 CFR 5.31 - Designation of authorized officials.

Code of Federal Regulations, 2010 CFR

2010-10-01

... of the Office of Human Development Services, the Family Support Administration, or any organizational... (Communications), who also is the PHS Freedom of Information Officer, may determine whether to release or deny the... Communications, HIH, who also is the NIH Freedom of Information Officer, may determine whether to release or deny...

32 CFR 310.22 - Non-consensual conditions of disclosure.

Code of Federal Regulations, 2012 CFR

2012-07-01

...). (15) Length of military service. (16) Basic Pay Entry Date. (17) Official Photo. (B) All disclosures... accordance with OPM release policies (see 5 CFR part 293.311). (ii) Military members. (A) While it is not possible to identify categorically information that must be released or withheld from military personnel...

Generation of insulin-producing cells from human bone marrow-derived mesenchymal stem cells: comparison of three differentiation protocols.

PubMed

Gabr, Mahmoud M; Zakaria, Mahmoud M; Refaie, Ayman F; Khater, Sherry M; Ashamallah, Sylvia A; Ismail, Amani M; El-Badri, Nagwa; Ghoneim, Mohamed A

2014-01-01

Many protocols were utilized for directed differentiation of mesenchymal stem cells (MSCs) to form insulin-producing cells (IPCs). We compared the relative efficiency of three differentiation protocols. Human bone marrow-derived MSCs (HBM-MSCs) were obtained from three insulin-dependent type 2 diabetic patients. Differentiation into IPCs was carried out by three protocols: conophylline-based (one-step protocol), trichostatin-A-based (two-step protocol), and β -mercaptoethanol-based (three-step protocol). At the end of differentiation, cells were evaluated by immunolabeling for insulin production, expression of pancreatic endocrine genes, and release of insulin and c-peptide in response to increasing glucose concentrations. By immunolabeling, the proportion of generated IPCs was modest ( ≃ 3%) in all the three protocols. All relevant pancreatic endocrine genes, insulin, glucagon, and somatostatin, were expressed. There was a stepwise increase in insulin and c-peptide release in response to glucose challenge, but the released amounts were low when compared with those of pancreatic islets. The yield of functional IPCs following directed differentiation of HBM-MSCs was modest and was comparable among the three tested protocols. Protocols for directed differentiation of MSCs need further optimization in order to be clinically meaningful. To this end, addition of an extracellular matrix and/or a suitable template should be attempted.

Volcano-hazards Education for Emergency Officials Through Study Trip Learning—The 2013 Colombia-USA Bi-national Exchange

NASA Astrophysics Data System (ADS)

Driedger, C. L.; Ewert, J. W.

2015-12-01

A central tenant of hazard communication is that colleagues with principal responsibilities for emergency planning and response sustain a 'long-term conversation' that builds trust, and increases understanding of hazards and successful protocols. This requires well maintained partnerships among a broad spectrum of officials who are knowledgeable about volcano hazards; credible within their communities; and who have personal and professional stake in their community's safety. It can require that volcano scientists facilitate learning opportunities for partners in emergency management who have little or no familiarity with eruption response. Scientists and officials from Colombia and the Cascades region of the United States recognized that although separated by geographic and cultural distance, their communities faced similar hazards from lahars. For the purpose of sharing best practices, the 2013 Colombia-USA Bi-national Exchange was organized by the US Geological Survey (USGS) and the Washington Emergency Management Division, with support from the US Agency for International Development (USAID). Nine Colombian emergency officials and scientists visited the U.S. to observe emergency response planning and protocols and to view the scale of a potential lahar disaster at Mount Rainier. Ten U.S. delegates visited Colombia to absorb best practices developed after the catastrophic 1985 eruption and lahars at Nevado del Ruiz. They observed the devastation and spoke with survivors, first responders, and emergency managers responsible for post-disaster recovery efforts. Delegates returned to their nations energized and with improved knowledge about volcanic crises and effective mitigation and response. In the U.S., trainings, hazard signage, evacuation routes and assembly points, and community websites have gained momentum. Colombian officials gained a deeper appreciation of and a renewed commitment to response planning, education, and disaster preparedness.

Anticipation and Controversy Surround "Superman" Release

ERIC Educational Resources Information Center

Aarons, Dakarai I.

2010-01-01

Well in advance of its official release, the education film "Waiting For Superman" has attracted a level of attention that could make it one of the year's most-watched documentaries--and one of the most controversial among educators, some of whom question its depictions of the American school system and how to improve it. Made by…

32 CFR 720.31 - Production of official records in the absence of court order.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Advocates General (Civil Law) and (Military Law) shall make determinations concerning the release of the... (Military Law) for determination, except that Privacy Act requests for release shall be forwarded to the Assistant Judge Advocate General (Civil Law) for determination. (2) Court-martial records and Articles 69...

32 CFR 720.31 - Production of official records in the absence of court order.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Advocates General (Civil Law) and (Military Law) shall make determinations concerning the release of the... (Military Law) for determination, except that Privacy Act requests for release shall be forwarded to the Assistant Judge Advocate General (Civil Law) for determination. (2) Court-martial records and Articles 69...

32 CFR 720.31 - Production of official records in the absence of court order.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Advocates General (Civil Law) and (Military Law) shall make determinations concerning the release of the... (Military Law) for determination, except that Privacy Act requests for release shall be forwarded to the Assistant Judge Advocate General (Civil Law) for determination. (2) Court-martial records and Articles 69...

32 CFR 720.31 - Production of official records in the absence of court order.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Advocates General (Civil Law) and (Military Law) shall make determinations concerning the release of the... (Military Law) for determination, except that Privacy Act requests for release shall be forwarded to the Assistant Judge Advocate General (Civil Law) for determination. (2) Court-martial records and Articles 69...

32 CFR 720.31 - Production of official records in the absence of court order.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Advocates General (Civil Law) and (Military Law) shall make determinations concerning the release of the... (Military Law) for determination, except that Privacy Act requests for release shall be forwarded to the Assistant Judge Advocate General (Civil Law) for determination. (2) Court-martial records and Articles 69...

Biosafety assessment protocols for new organisms in New Zealand: Can they apply internationally to emerging technologies?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barratt, B.I.P.; Moeed, A.; Malone, L.A.

2006-05-15

An analysis of established biosafety protocols for release into the environment of exotic plants and biological control agents for weeds and arthropod pests has been carried out to determine whether such protocols can be applied to relatively new and emerging technologies intended for the primary production industries, such as transgenic plants. Example case studies are described to indicate the scope of issues considered by regulators who make decisions on new organism releases. No transgenic plants have been released to date in New Zealand, but two field test approvals are described as examples. An analysis of the biosafety protocols has shownmore » that, while many of the risk criteria considered for decision-making by regulators are similar for all new organisms, a case-by-case examination of risks and potential impacts is required in order to fully assess risk. The value of post-release monitoring and validation of decisions made by regulators is emphasised.« less

Specification, Synthesis, and Verification of Software-based Control Protocols for Fault-Tolerant Space Systems

DTIC Science & Technology

2016-08-16

Force Research Laboratory Space Vehicles Directorate AFRL /RVSV 3550 Aberdeen Ave, SE 11. SPONSOR/MONITOR’S REPORT Kirtland AFB, NM 87117-5776 NUMBER...Ft Belvoir, VA 22060-6218 1 cy AFRL /RVIL Kirtland AFB, NM 87117-5776 2 cys Official Record Copy AFRL /RVSV/Richard S. Erwin 1 cy... AFRL -RV-PS- AFRL -RV-PS- TR-2016-0112 TR-2016-0112 SPECIFICATION, SYNTHESIS, AND VERIFICATION OF SOFTWARE-BASED CONTROL PROTOCOLS FOR FAULT-TOLERANT

An extremely compensatible cigarette by design: documentary evidence on industry awareness and reactions to the Barclay filter design cheating the tar testing system

PubMed Central

Kozlowski, L; Dreschel, N; Stellman, S; Wilkenfeld, J; Weiss, E; Goldberg, M

2005-01-01

Background: The Barclay cigarette (Brown & Williamson) was introduced in 1980 in the USA in the most expensive launch in history. In the USA and around the world, Barclay was later determined to have a grooved filter design that was compromised by human smokers in the normal act of smoking, but that was measured as ultra-low tar using the standard tar testing protocol. Objectives: To evaluate whether Brown & Williamson knew of the compensatability of Barclay during the design process and before it was released; to evaluate initial responses of competing tobacco companies to Barclay, before complaints were made to the Federal Trade Commission in 1981. Methods: Internet databases of industry documents (Tobacco Documents Online, Legacy Tobacco Documents Library, Brown & Williamson Litigation discovery website, Guildford and major company websites) were searched using key words, key dates, and targeted searches. Documents related specifically to the development, evaluation and release of the Barclay cigarette and related to the responses by competing tobacco companies were examined. Results: Documents indicate the manufacturer was aware of Barclay design problems and was planning, before release, to respond to criticism. Competing companies quickly detected the filter groove stratagem and considered developing their own similar filter, but eventually backed off. Conclusion: The design problems with Barclay were readily understood by cigarette manufacturers, including the maker of Barclay, before official governmental evaluations occurred. Testing involving measured exposures to human smokers may in the end be crucial to identifying problems with novel cigarette designs. PMID:15735303

Education Department Effort to Prevent Colleges from Releasing Crime Records Suffers Setback.

ERIC Educational Resources Information Center

Jaschik, Scott

1991-01-01

The Department of Education has suffered legal defeats in Missouri and Arkansas in its campaign to prevent colleges from publicly releasing names of students arrested by campus security. Controversy involves interpretation of a 1974 privacy-protection law, the Buckley Amendment. College officials are unsure about how to deal with the issue. (MSE)

Official 1997 Mock Trial Materials for the Twenty-Fifth Annual District of Columbia Public Schools Mock Trail Program: Ricki Jones, Plaintiff v. Metro City, Defendant.

ERIC Educational Resources Information Center

Henderson, Kamina A.; Roe, Richard L.

This packet of materials contains law-related materials for students to conduct a mock trial. In this case a faulty water system, containing the parasite Pindia, contributed to the death of an AIDS patient. Statements from the plaintiff, a representative of the Metro City Water Department, health officials, and others are presented. New releases,…

The Observation of Bahasa Indonesia Official Computer Terms Implementation in Scientific Publication

NASA Astrophysics Data System (ADS)

Gunawan, D.; Amalia, A.; Lydia, M. S.; Muthaqin, M. I.

2018-03-01

The government of the Republic of Indonesia had issued a regulation to substitute computer terms in foreign language that have been used earlier into official computer terms in Bahasa Indonesia. This regulation was stipulated in Presidential Decree No. 2 of 2001 concerning the introduction of official computer terms in Bahasa Indonesia (known as Senarai Padanan Istilah/SPI). After sixteen years, people of Indonesia, particularly for academics, should have implemented the official computer terms in their official publications. This observation is conducted to discover the implementation of official computer terms usage in scientific publications which are written in Bahasa Indonesia. The data source used in this observation are the publications by the academics, particularly in computer science field. The method used in the observation is divided into four stages. The first stage is metadata harvesting by using Open Archive Initiative - Protocol for Metadata Harvesting (OAI-PMH). Second, converting the harvested document (in pdf format) to plain text. The third stage is text-preprocessing as the preparation of string matching. Then the final stage is searching the official computer terms based on 629 SPI terms by using Boyer-Moore algorithm. We observed that there are 240,781 foreign computer terms in 1,156 scientific publications from six universities. This result shows that the foreign computer terms are still widely used by the academics.

13 CFR 102.2 - Public reading rooms.

Code of Federal Regulations, 2011 CFR

2011-01-01

... adjudicating a case, (2) Official non-privileged policy statements, opinions, or interpretations, (3) Standard operating procedures affecting members of the public, (4) Records SBA has released in response to previous...

13 CFR 102.2 - Public reading rooms.

Code of Federal Regulations, 2013 CFR

2013-01-01

... adjudicating a case, (2) Official non-privileged policy statements, opinions, or interpretations, (3) Standard operating procedures affecting members of the public, (4) Records SBA has released in response to previous...

13 CFR 102.2 - Public reading rooms.

Code of Federal Regulations, 2012 CFR

2012-01-01

... adjudicating a case, (2) Official non-privileged policy statements, opinions, or interpretations, (3) Standard operating procedures affecting members of the public, (4) Records SBA has released in response to previous...

13 CFR 102.2 - Public reading rooms.

Code of Federal Regulations, 2014 CFR

2014-01-01

... adjudicating a case, (2) Official non-privileged policy statements, opinions, or interpretations, (3) Standard operating procedures affecting members of the public, (4) Records SBA has released in response to previous...

Pacific Southwest Media Center

EPA Pesticide Factsheets

News media, state and local officials, and others can find press releases, media events and contacts in EPA's Pacific Southwest. Additional resources include newsletters, annual reports, and library services that support regional activities.

OIG News Release: EPA IG responds to Sen. Vitter's letter about audit report on agency's use of private and alias email accounts to conduct official business

EPA Pesticide Factsheets

Arthur A. Elkins Jr., Inspector General for the U.S. Environmental Protection Agency, has replied to a letter signed and released to the public February 20 byU.S. Sen. David Vitter, Ranking Member of the Senate Committee on Environment and Public Works.

Diffusion and Mechanical Properties of Polyether-Polyurethanes Reinforced with Silica

DTIC Science & Technology

2016-05-01

with Silica by James M Sloan and Henry Feuer Approved for public release; distribution is unlimited. NOTICES...Directorate, ARL Henry Feuer TKC Global Inc., Aberdeen Proving Ground, MD Approved for public release; distribution is...unlimited. FOR OFFICIAL USE ONLY (delete if not FOUO) ii REPORT DOCUMENTATION PAGE Form Approved OMB No. 0704-0188 Public reporting burden for this

The release of Doxorubicin from liposomes monitored by MRI and triggered by a combination of US stimuli led to a complete tumor regression in a breast cancer mouse model.

PubMed

Rizzitelli, S; Giustetto, P; Faletto, D; Delli Castelli, D; Aime, S; Terreno, E

2016-05-28

The work aimed at developing a novel MRI-based theranostic protocol for improving the anticancer efficacy of a Doxil-like liposomal formulation. The goal was achieved stimulating the intratumor release of the drug from the nanocarrier and favoring its diffusion in the lesion by the sequential application of low-intensity pulsed ultrasound. The protocol was tested on mice bearing a syngeneic breast cancer model. The combination of acoustic waves with different characteristics allowed for: i) the release of the drug and the co-encapsulated MRI agent (Gadoteridol) from the liposomes in the vessels of the tumor region, and ii) the extravasation of the released material, as well as intact liposomes, in the tumor stroma. The MR-T1 contrast enhancement measured in the tumor reported on the delivery and US-triggered release of Doxorubicin. The developed protocol resulted in a marked increase in the intratumor drug concentration that, in turn, led to the complete regression of the lesion. The protocol has a good clinical translatability because all the components of the theranostic agent (Doxorubicin, liposomes, Gadoteridol) are approved for human use. Copyright © 2016 Elsevier B.V. All rights reserved.

ACHP | Preserve America Community and Neighborhood Designations

Science.gov Websites

tourism programs. Benefits of designation include: White House recognition; a certificate of recognition ; inclusion in national and regional press releases; official notification of designation to State tourism

EPA's On-Scene Coordinators (OSCs)

EPA Pesticide Factsheets

These are the federal officials responsible for monitoring or directing responses to all oil spills and hazardous substance releases reported to the government. They are responsible for assessment, monitoring, response assistance, and evaluation.

Efficacy of a Creon delayed-release pancreatic enzyme protocol for clearing occluded enteral feeding tubes.

PubMed

Stumpf, Janice L; Kurian, Rebecca M; Vuong, Jennifer; Dang, Kimberlyn; Kraft, Michael D

2014-04-01

Alkalinized Viokase pancreatic enzyme tablets restored patency to 71.9% of occluded Dobhoff tubes in a prospective study. After removal of Viokase tablets from the US market, the hospital protocol for unclogging enteral feeding tubes was adapted to use Creon pancreatic enzyme delayed-release capsules, despite the lack of published data. To evaluate the effectiveness of a Creon-based protocol to clear occluded enteral feeding tubes. This retrospective study included all adult and pediatric patients seen in the emergency department or in an inpatient setting who received Creon 12 000 units lipase delayed-release capsule dissolved in a solution of sodium bicarbonate 650 mg and sterile water for clearing occluded enteral feeding tubes between May 1 and November 30, 2010. The Creon protocol was deemed effective if tube clearance was documented in the medical record or if enteral feedings were resumed with no note regarding tube replacement. Alkalinized Creon delayed-release capsules were administered to 83 patients with a total of 118 clogged tubes. Three poorly documented cases and 5 tubes with mechanical clogs were excluded from data analysis. Patency was restored to 53 of 110 (48.2%) occluded tubes. More than 1 treatment course was attempted in 5 cases, with success in 3. An alkalinized Creon pancreatic enzyme protocol was effective in clearing approximately half of the occluded enteral feeding tubes in this retrospective study, an efficacy rate much less than that previously reported in the literature with a Viokase-based protocol.

World Organisation for Animal Health

MedlinePlus

... Our members Delegates Key texts Basic texts Cooperation agreements Official Acts Resolutions and recommendations Final Reports of ... information: press releases, fact sheets, infographics… Partners Collaboration agreements with regional and world organisations of a public ...

41 CFR 109-43.307-2.50 - Monitoring of hazardous personal property.

Code of Federal Regulations, 2010 CFR

2010-07-01

... personal property shall be checked for contamination by environmental, safety, and health officials. Contamination-free personal property will be tagged with a certification tag authorizing release for transfer or...

12 CFR 510.5 - Release of unpublished OTS information.

Code of Federal Regulations, 2011 CFR

2011-01-01

... testimony or informal interview, that was acquired in the course of performing official duties or because of... wish to question the witness beyond the authorized scope should request expanded authorization pursuant...

NanoRelease: Pilot interlaboratory comparison of a weathering protocol applied to resilient and labile polymers with and without embedded carbon nanotubes

EPA Science Inventory

A major use of multi-walled carbon nanotubes (MWCNTs) is as functional fillers embedded in a solid matrix, such as plastics or coatings. Weathering and abrasion of the solid matrix during use can lead to environmental releases of the MWCNTs. Here we focus on a protocol to identif...

A simplified protocol for molecular identification of Eimeria species in field samples.

PubMed

Haug, Anita; Thebo, Per; Mattsson, Jens G

2007-05-15

This study aimed to find a fast, sensitive and efficient protocol for molecular identification of chicken Eimeria spp. in field samples. Various methods for each of the three steps of the protocol were evaluated: oocyst wall rupturing methods, DNA extraction methods, and identification of species-specific DNA sequences by PCR. We then compared and evaluated five complete protocols. Three series of oocyst suspensions of known number of oocysts from Eimeria mitis, Eimeria praecox, Eimeria maxima and Eimeria tenella were prepared and ground using glass beads or mini-pestle. DNA was extracted from ruptured oocysts using commercial systems (GeneReleaser, Qiagen Stoolkit and Prepman) or phenol-chloroform DNA extraction, followed by identification of species-specific ITS-1 sequences by optimised single species PCR assays. The Stoolkit and Prepman protocols showed insufficient repeatability, and the former was also expensive and relatively time-consuming. In contrast, both the GeneReleaser protocol and phenol-chloroform protocols were robust and sensitive, detecting less than 0.4 oocysts of each species per PCR. Finally, we evaluated our new protocol on 68 coccidia positive field samples. Our data suggests that rupturing the oocysts by mini-pestle grinding, preparing the DNA with GeneReleaser, followed by optimised single species PCR assays, makes a robust and sensitive procedure for identifying chicken Eimeria species in field samples. Importantly, it also provides minimal hands-on-time in the pre-PCR process, lower contamination risk and no handling of toxic chemicals.

78 FR 54945 - Privacy Act; System of Records: Protocol Records, State-33

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-06

... accounting of those U.S. government officials receiving gifts and decorations from foreign governments and to....C. 2625, 22 U.S.C. 4301 et seq. PURPOSE: The information in this system of records is an accounting... public and professional institutions possessing relevant information. SYSTEMS EXEMPTED FROM CERTAIN...

Panama: Owning the Canal

DTIC Science & Technology

2014-03-01

tourist destination. The handbook reveals “a Korean/American consortium signed a deal with the [Panamanian] Government to invest nearly $400 million...the official policy or position of the Department of Defense or the U.S. Government . IRB protocol number ____N/A____. 12a. DISTRIBUTION...Credible, and Capable Governments ........................102 VII. CONCLUSION

42 CFR 93.407 - HHS administrative actions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON... cooperative agreement. (6) Special review of all requests for PHS funding. (7) Imposition of supervision... PHS funding component, and the debarring official. ...

Underway Recovery Test 6 (URT-6)

NASA Image and Video Library

2018-01-21

NASA's Recovery Team worked with the U.S. Navy during Underway Recovery Test 6 (URT-6) aboard the USS Anchorage off the coast of San Diego California -- First official release day with Captain and Astronaut interviews.

Determination of barge impact probabilities for bridge design.

DOT National Transportation Integrated Search

2016-04-01

Waterway bridges in the United States are designed to resist vessel collision loads according to design provisions released by the American Association of State : Highway and Transportation Officials (AASHTO). These provisions provide detailed proced...

12 CFR 510.5 - Release of unpublished OTS information.

Code of Federal Regulations, 2010 CFR

2010-01-01

... their official capacities. Examples of unpublished information include: (i) Information in the memory of... must be sent to the OTS at 1700 G Street NW., Washington, DC 20552, to the attention of the Corporate...

The experiences of parents who report youth bullying victimization to school officials.

PubMed

Brown, James R; Aalsma, Matthew C; Ott, Mary A

2013-02-01

Current research offers a limited understanding of parental experiences when reporting bullying to school officials. This research examines the experiences of middle-school parents as they took steps to protect their bullied youth. The qualitative tradition of interpretive phenomenology was used to provide in-depth analysis of the phenomena. A criterion-based, purposeful sample of 11 parents was interviewed face-to-face with subsequent phone call follow-ups. Interviews were taped, transcribed, and coded. MAX qda software was used for data coding. In analyzing the interviews, paradigm cases, themes, and patterns were identified. Three parent stages were found: discovering, reporting, and living with the aftermath. In the discovery stage, parents reported using advice-giving in hopes of protecting their youth. As parents noticed negative psychosocial symptoms in their youth escalate, they shifted their focus to reporting the bullying to school officials. All but one parent experienced ongoing resistance from school officials in fully engaging the bullying problem. In the aftermath, 10 of the 11 parents were left with two choices: remove their youth from the school or let the victimization continue. One paradigm case illustrates how a school official met parental expectations of protection. This study highlights a parental sense of ambiguity of school officials' roles and procedures related to school reporting and intervention. The results of this study have implications in the development and use of school-wide bullying protocols and parental advocacy.

Leaks to the Press as Communication within and between Organizations.

ERIC Educational Resources Information Center

Kielbowicz, Richard B.

1980-01-01

Examines news leaks--the calculated release of information by anonymous officials--as a means by which the mass media have been annexed to perform some of the functions of organizational and interorganizational communication. (RL)

40 CFR 1400.8 - Access to off-site consequence analysis information by Federal government officials.

Code of Federal Regulations, 2010 CFR

2010-07-01

... ENVIRONMENTAL PROTECTION AGENCY AND DEPARTMENT OF JUSTICE ACCIDENTAL RELEASE PREVENTION REQUIREMENTS; RISK MANAGEMENT PROGRAMS UNDER THE CLEAN AIR ACT SECTION 112(r)(7); DISTRIBUTION OF OFF-SITE CONSEQUENCE ANALYSIS...

HEALTH-SCREENING PROTOCOLS FOR VINACEOUS AMAZONS (AMAZONA VINACEA) IN A REINTRODUCTION PROJECT.

PubMed

Saidenberg, André B S; Zuniga, Eveline; Melville, Priscilla A; Salaberry, Sandra; Benites, Nilson R

2015-12-01

Reintroduction is a growing field in the conservation of endangered species. The vinaceous Amazon parrot (Amazona vinacea) is extinct in several areas, and a project to release confiscated individuals to their former range is currently underway. The objective of this study was to evaluate and improve the selection and treatment of individual release candidates by detecting possible pathogen carriers using samples taken before and during release. As part of prerelease health protocols, samples were obtained from 29 parrots on three different occasions while in captivity and once after their release. Samples were screened for paramyxovirus type 1, avian influenza, poxvirus, coronavirus, psittacine herpesvirus 1, Chlamydia psittaci , enteropathogenic Escherichia coli (EPEC), Salmonella spp., and endoparasites. The majority of samples returned negative results, with the exception of two individuals that tested positive for C. psittaci in the first sampling and for Ascaridia spp. in the second pooled sampling. Treatments for C. psittaci and endoparasites were administered prior to release, and negative results were obtained in subsequent exams. The number of positive results for E. coli (non-EPEC) decreased during the rehabilitation period. Adequate quarantine procedures and health examinations greatly minimize disease risks. The protocols employed in this study resulted in acceptable health status in accordance with current environmental legislation in Brazil. Additionally, protocols allowed informed decisions to release candidates, minimized risks, and favored the selection of healthy individuals, thereby contributing to the recovery of this species. It is important to determine appropriate minimum health-screening protocols when advanced diagnostics may not be available or high costs make the tests prohibitive in countries where confiscations occur. We hypothesize that a minimum panel of tests of pooled samples can serve as an alternative approach that minimizes costs and overall workload and supports projects intended to restore and promote flagship species and hamper their illegal trade.

Preparticipation Screening of Athletic Officials: SEC Football Referees at Risk.

PubMed

Turner, John L; Walters, Rod; Leski, Mark J; Saywell, Robert M; Wooldridge, J Scott

2003-03-01

Although preparticipation screening for athletes is commonplace, few studies have addressed the issue for those officiating at games. To review current data on physiologic stress on sports officials, to obtain prevalence data on health parameters for football officials, and to determine the outcomes when screening criteria are applied in preseason exams. A protocol was established using health history questionnaires and physical exams with laboratory screening to assess the health of all football officials working in the Southeastern Conference (SEC) from 1997 to 2000. The main outcome measure was the prevalence of cardiac risk factors as determined by American College of Sports Medicine guidelines. Initial screening of 102 football officials revealed that 10.1% of SEC referees had elevated systolic blood pressure, 13.9% had elevated diastolic blood pressure, and 3.8% had resting tachycardia. Average body mass index (BMI) was 28.6 kg/m2, with 87.3% having a BMI that exceeded 25 (overweight). About one-third (31.6%) had a BMI greater than 30 (obese). Total fasting cholesterol exceeded 200 mg/dL in 44.2%, HDL levels were below 35 mg/dL in 34.3%, and LDL levels were above 120 mg/dL in 62.3%. Compared with age-adjusted national data, there were more overweight and more obese officials, but they had lower systolic and diastolic blood pressures and lower mean total cholesterol levels. Using the Framingham Study prediction model to estimate coronary heart disease (CHD) risk, analysis revealed that referees had a lower risk than the national 10-year CHD risk but a higher risk compared with that of the low-risk population. These data reveal a greater need for graded exercise testing. The higher rates of obesity among officials will promote further screening for CHD risk factors.

Protocols for Automated Protist Analysis

DTIC Science & Technology

2011-12-01

Report No: CG-D-14-13 Protocols for Automated Protist Analysis December 2011 Distribution Statement A: Approved for public...release; distribution is unlimited. Protocols for Automated Protist Analysis ii UNCLAS//Public | CG-926 RDC | B. Nelson, et al. | Public...Director United States Coast Guard Research & Development Center 1 Chelsea Street New London, CT 06320 Protocols for Automated Protist Analysis

Interoperability in the Planetary Science Archive (PSA)

NASA Astrophysics Data System (ADS)

Rios Diaz, C.

2017-09-01

The protocols and standards currently being supported by the recently released new version of the Planetary Science Archive at this time are the Planetary Data Access Protocol (PDAP), the EuroPlanet- Table Access Protocol (EPN-TAP) and Open Geospatial Consortium (OGC) standards. We explore these protocols in more detail providing scientifically useful examples of their usage within the PSA.

40 CFR 1036.530 - Calculating greenhouse gas emission rates.

Code of Federal Regulations, 2013 CFR

2013-07-01

... measured test fuel properties as specified in this paragraph (b) to obtain the official emission results... differences in test fuels within a fuel type. Use good engineering judgment to develop and apply testing protocols to minimize the impact of variations in test fuels. (1) For liquid fuels, determine the net energy...

40 CFR 1036.530 - Calculating greenhouse gas emission rates.

Code of Federal Regulations, 2012 CFR

2012-07-01

... measured test fuel properties as specified in this paragraph (b) to obtain the official emission results... differences in test fuels within a fuel type. Use good engineering judgment to develop and apply testing protocols to minimize the impact of variations in test fuels. (1) For liquid fuels, determine the net energy...

40 CFR 1036.530 - Calculating greenhouse gas emission rates.

Code of Federal Regulations, 2014 CFR

2014-07-01

... measured test fuel properties as specified in this paragraph (b) to obtain the official emission results... differences in test fuels within a fuel type. Use good engineering judgment to develop and apply testing protocols to minimize the impact of variations in test fuels. (1) For liquid fuels, determine the net energy...

Biosecurity protocols for heritage gardens

Treesearch

Ian Wright; David Slawson

2010-01-01

This project aims to protect The National Trust (NT) from the increasing number of harmful plant pests and diseases that slip though official controls and threaten our gardens, plant collections and landscapes. During 2008, the National Trust (NT) with the seconded help of Dr. David Slawson, Head of Pest and Disease Identification Programme, Food and Environment...

47 CFR 1.10014 - What happens after officially filing my application?

Code of Federal Regulations, 2010 CFR

2010-10-01

... ARC-xxxxx Foreign Carrier Affiliation Notification FCN-xxxxx International High Frequency IHF-xxxxx... PN released International High Frequency IHF-xxxxx International Public Fixed IPF-xxxxx Recognized... Foreign Carrier Affiliation Notification. International High Frequency: Construction Permits,Licenses...

47 CFR 1.10014 - What happens after officially filing my application?

Code of Federal Regulations, 2011 CFR

2011-10-01

... ARC-xxxxx Foreign Carrier Affiliation Notification FCN-xxxxx International High Frequency IHF-xxxxx... PN released International High Frequency IHF-xxxxx International Public Fixed IPF-xxxxx Recognized... Foreign Carrier Affiliation Notification. International High Frequency: Construction Permits,Licenses...

EPA Provides Training to Help Communities Prepare for Climate Change

EPA Pesticide Factsheets

WASHINGTON - As part of President Obama's Climate Action Plan, the U.S. Environmental Protection Agency (EPA) today released an online training module to help local government officials take actions to increase their communities' resiliency to a chan

Physically Protected Spread Spectrum Communications

DTIC Science & Technology

2016-04-14

Kirtland AFB, NM 87117-5776 NUMBER(S) AFRL -RV-PS-TR-2016-0046 12. DISTRIBUTION / AVAILABILITY STATEMENT Approved for public release; distribution... AFRL /RVIL Kirtland AFB, NM 87117-5776 2 cys Official Record Copy AFRL /RVSW/Khanh Pham 1 cy 38 Approved for public release; distribution is unlimited. (This page intentionally left blank) ... AFRL -RV-PS- AFRL -RV-PS- TR-2016-0046 TR-2016-0046 PHYSICALLY PROTECTED SPREAD SPECTRUM COMMUNICATIONS Hyuck M. Kwon Wichita State

A Study on the Feasibility of Creating a Web-Accessible Marine Mammal Sound Library Based upon the Collections at the Woods Hole Oceanographic Institution

DTIC Science & Technology

2008-09-01

NPS-OC-08-005 NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA Approved for public release; distribution is...official policy or position of the Department of Defense or the U.S. Government. 12a. DISTRIBUTION / AVAILABILITY STATEMENT Approved for public...release; distribution is unlimited. 12b. DISTRIBUTION CODE 13. ABSTRACT (maximum 200 words) A universally accessible web-based marine

An Examination of State and Local Fusion Centers and Data Collection Methods

DTIC Science & Technology

2008-03-01

problems that are active in their area so their skills will remain sharp. He offered prison gangs a one potential area of investigation. Many ... Many documents are prepared and released at the Law Enforcement Sensitive level (LES) while others are prepared and released at the For Official Use ...jihadist terrorists were the result of a domestic cell . These threats come in many forms, such as radicalized prisoners, homegrown jihadists

JEWEL 2.0.0: directions for use

NASA Astrophysics Data System (ADS)

Zapp, Korinna

2014-02-01

In this publication the first official release of the Jewel 2.0.0 code [The first version Jewel 1 (Zapp et al. in Eur Phys J C 60:617, 2009) could only treat elastic scattering explicitly and the code was never published, The code can be downloaded from the official Jewel homepage http://jewel.hepforge.org] is presented. Jewel is a Monte Carlo event generator simulating QCD jet evolution in heavy-ion collisions. It treats the interplay of QCD radiation and re-scattering in a medium with fully microscopic dynamics in a consistent perturbative framework with minimal assumptions. After a qualitative introduction into the physics of Jewel detailed information about the practical aspects of using the code is given. The code is available from the official Jewel homepage http://jewel.hepforge.org.

Systematic Review Protocol for the IRIS Chloroform Assessment (Inhalation) (Preliminary Assessment Materials)

EPA Science Inventory

In January 2018, EPA released the Systematic Review Protocol for the IRIS Chloroform Assessment (Inhalation). As part of developing a draft IRIS assessment, EPA presents a methods document, referred to as the protocol, for conducting a chemical-specific systematic revie...

Chinese traffic fatalities and injuries in police reports, hospital records, and in-depth records from one city.

PubMed

Qiu, Jun; Zhou, Jihong; Zhang, Liang; Yao, Yuan; Yuan, Danfeng; Shi, Jianguo; Gao, Zhiming; Zhou, Lin; Wang, Zhengguo; Evans, Leonard

2015-01-01

Claims of sharp reductions in Chinese traffic casualties after 2002 based on police-reported data have been questioned in the literature. The objective of this study is to determine whether a decline in casualties occurred and to better understand the police data. The first of 2 unrelated studies analyzed data from 210 military hospitals throughout China providing records for inpatients injured in traffic accidents (2001-2007). The second compared in-depth crash records (2000-2006) from one city to officially released data. Hospital data showed that casualties increased from 2002 to 2007. The city investigation showed consistently far more fatalities and injuries in the in-depth data than officially released. For example, in-depth data showed 1,720 fatalities. Only 557 of these were reported officially (data loss = 68%). Disaggregating into 3 regions showed a data loss of 41% in urban areas, 63% in rural areas, and 90% in rural-urban fringe zones. For injuries, data losses were even greater. Traffic fatalities and injuries did not decrease from 2002 to 2006. The in-depth city data contained 3 times as many fatalities and 5 times as many injuries as reported by police. Reasons why this occurred and suggestions to improve data collection and reduce casualties are given.

47 CFR 1.10014 - What happens after officially filing my application?

Code of Federal Regulations, 2013 CFR

2013-10-01

... Frequency IHF-xxxxx. Recognized Operating Agency ROA-xxxxx. Satellite Space Station SAT-xxxxx. Satellite... PN released. International High Frequency IHF-xxxxx. Recognized Operating Agency No action taken PN... Carrier Affiliation Notification. International High Frequency: Construction Permits, Licenses...

47 CFR 1.10014 - What happens after officially filing my application?

Code of Federal Regulations, 2014 CFR

2014-10-01

... Frequency IHF-xxxxx. Recognized Operating Agency ROA-xxxxx. Satellite Space Station SAT-xxxxx. Satellite... PN released. International High Frequency IHF-xxxxx. Recognized Operating Agency No action taken PN... Carrier Affiliation Notification. International High Frequency: Construction Permits, Licenses...

47 CFR 1.10014 - What happens after officially filing my application?

Code of Federal Regulations, 2012 CFR

2012-10-01

... Frequency IHF-xxxxx. Recognized Operating Agency ROA-xxxxx. Satellite Space Station SAT-xxxxx. Satellite... PN released. International High Frequency IHF-xxxxx. Recognized Operating Agency No action taken PN... Carrier Affiliation Notification. International High Frequency: Construction Permits, Licenses...

43 CFR 426.22 - Public participation.

Code of Federal Regulations, 2010 CFR

2010-10-01

... the form of news releases, legal notices, official letters, memoranda, or other forms of written... coordinated with those involved with National Environmental Policy Act compliance, if Reclamation determines that the contract action may or will have “significant” environmental effects. (f) Individuals...

43 CFR 426.22 - Public participation.

Code of Federal Regulations, 2014 CFR

2014-10-01

... the form of news releases, legal notices, official letters, memoranda, or other forms of written... coordinated with those involved with National Environmental Policy Act compliance, if Reclamation determines that the contract action may or will have “significant” environmental effects. (f) Individuals...

43 CFR 426.22 - Public participation.

Code of Federal Regulations, 2011 CFR

2011-10-01

... the form of news releases, legal notices, official letters, memoranda, or other forms of written... coordinated with those involved with National Environmental Policy Act compliance, if Reclamation determines that the contract action may or will have “significant” environmental effects. (f) Individuals...

43 CFR 426.22 - Public participation.

Code of Federal Regulations, 2013 CFR

2013-10-01

... the form of news releases, legal notices, official letters, memoranda, or other forms of written... coordinated with those involved with National Environmental Policy Act compliance, if Reclamation determines that the contract action may or will have “significant” environmental effects. (f) Individuals...

43 CFR 426.22 - Public participation.

Code of Federal Regulations, 2012 CFR

2012-10-01

... news releases, legal notices, official letters, memoranda, or other forms of written material; and (3... coordinated with those involved with National Environmental Policy Act compliance, if Reclamation determines that the contract action may or will have “significant” environmental effects. (f) Individuals...

Beware of Illegally Marketed Diabetes Treatments

MedlinePlus

... exercise program,” Humbert said. Health care professionals and consumers should report any problems or reactions—often referred to as ... Continuing Education Inspections & Compliance Federal, State & Local Officials ... Content Home Latest Recalls Report an Adverse Event MedWatch Safety Alerts News Releases ...

Think Before You Ink: Are Tattoos Safe?

MedlinePlus

... about the ink and your reaction and outcome. Reports from consumers are one of our most important sources of ... Continuing Education Inspections & Compliance Federal, State & Local Officials ... Content Home Latest Recalls Report an Adverse Event MedWatch Safety Alerts News Releases ...

Forensic Investigation of mass disasters in Nigeria: A review

PubMed Central

Obafunwa, John Oladapo; Faduyile, Francis Adedayo; Soyemi, Sunday Sokunle; Eze, Uwom Okereke; Nwana, Edmund J. C.; Odesanmi, William Olufemi

2015-01-01

This paper is to establish the present state of things in the country in terms of legal framework and the availability of personnel with a view to presenting an overview of proper mass disaster investigations. This is a retrospective review of mass disasters in Nigeria that occurred within the last 20 years. The study therefore reviews the state of the forensic investigation of the mass disasters as well as the efforts made to identify the victims of the disaster. The process of proper forensic investigation from the stage of evaluation of the scene and recovery process to the final identification of victims are presented to serve as a protocol for the country. The assessment of the present state of preparedness in Nigeria is also examined with a view to improving the practice to international standards. Data were retrieved from official documents from the aviation industry as well as Nigeria news reports. The standard protocols for disaster victim identification were retrieved from the guide released by the INTERPOL. The state of preparedness of the country and recommendations for improvement are presented. The Federal government and the states of the federation should without further delay put in place the process of reviewing the law of Coroner's system and provide the enabling environment for the proper forensic investigation. The training curriculum of the first responders should incorporate mass disaster investigations in order to produce efficient officers and personnel. A functional disaster victim identification (DVI) team is strongly advocated to incorporate different professionals involved in mass disaster management. PMID:25657485

Survival of captive-reared Hispaniolan Parrots released in Parque Nacional del Este, Dominican Republic

USGS Publications Warehouse

Collazo, J.A.; White, T.H.; Vilella, F.J.; Guerrero, S.A.

2003-01-01

We report first-year survival rates of 49 captive-reared Hispaniolan Parrots (Amazona ventralis) released in Parque Nacional del Este, Dominican Republic. Our goal was to learn about factors affecting postrelease survival. Specifically, we tested if survival was related to movements and whether modifying prerelease protocols influenced survival rates. We also estimated survival in the aftermath of Hurricane Georges (22 September 1998). Twenty-four parrots, fitted with radio-transmitters, were released between 14 September and 12 December 1997. Twenty-five more were released between 29 June and 16 September 1998. First-year survival rates were 30% in 1997 and 29% in 1998. Survival probability was related to bird mobility. In contrast to birds released in 1997, none of the 25 parrots released in 1998 suffered early postrelease mortality (i.e., 3-5 days after release). Two adjustments to prerelease protocols (increased exercise and reduced blood sampling) made in 1998 may have contributed to differences in mobility and survival between years. The reduction of early postrelease mortality in 1998 was encouraging, as was the prospect for higher first-year survival (e.g., 30% to 65%). Only one death was attributed to the immediate impact of the hurricane. Loss of foraging resources was likely a major contributor to ensuing mortality. Birds increased their mobility, presumably in search of food. Survival rates dropped 23% in only eight weeks posthurricane. This study underscores the value of standardized prerelease protocols, and of estimating survival and testing for factors that might influence it. Inferences from such tests will provide the best basis to make adjustments to a release program.

Simulation - McCandless, Bruce (Syncom IV)

NASA Image and Video Library

1985-04-15

S85-30800 (14 April 1985) --- Astronaut Bruce McCandless II tests one of the possible methods of attempting to activate a switch on the Syncom-IV (LEASAT) satellite released April 13 into space from the Space Shuttle Discovery. The communications spacecraft failed to behave properly upon release and NASA officials and satellite experts are considering possible means of repair. McCandless was using a full scale mockup of the satellite in the Johnson Space Center's (JSC) mockup and integration laboratory.

Materials Processing and Manufacturing Technologies for Diamond Substrates Multichip Modules

DTIC Science & Technology

1994-10-14

document are those of the authors and should not be intepreted as representing the official policies, either express or implied, of the Defense Advanced...release of the diamond at the end of the deposition step, "* deposition of non-uniform films for stress/flatness control. 75kW Reactor & Modelling Studies...too strong (the film releases partially or not at all) to too weak (the film delaminates during the run from growth stresses), and are continuing to

Armenia, Azerbaijan, and Georgia: Political Developments and Implications for U.S. Interests

DTIC Science & Technology

2011-04-15

of the diplomats] to implement in Azerbaijan the experiments of Arab countries, some of them should be declared persona non grata.” An official of...protections for human rights, including by releasing two Internet bloggers jailed for hooliganism in November 2009 (they were released in November 2010).6...the “frozen Nagorno Karabakh conflict,” in which “heightened rhetoric and distrust on both sides and violent incidents along the Line of Contact

Lead in the School's Drinking Water.

ERIC Educational Resources Information Center

Environmental Protection Agency, Washington, DC. Office of Water Programs.

The purpose of this manual is to assist school officials by providing information on the effects of lead in school drinking water on children, how to detect the presence of lead, how to reduce the lead, and how to provide training for sampling and remedial programs. A protocol is provided for procedures to determine the location and source of lead…

A Failure to Communicate

ERIC Educational Resources Information Center

Fredette, Michelle

2011-01-01

In April, Asia officially ran out of Internet Protocol (IP) version 4 addresses--the computer equivalent of running out of telephone numbers. Over the next couple of years, the rest of the world will also run dry. Yet, unlike the Y2K bug that had some people convinced the sky would fall, this particular problem is generating little more than tired…

Release of antioxidant capacity from five plant foods during a multistep enzymatic digestion protocol.

PubMed

Papillo, Valentina Azzurra; Vitaglione, Paola; Graziani, Giulia; Gokmen, Vural; Fogliano, Vincenzo

2014-05-07

This study aimed at elucidating the influence of food matrix on the release of antioxidant activity from five plant foods (apple, spinach, walnut, red bean, and whole wheat). To this purpose a protocol based on sequential enzymatic digestion was adopted. The total antioxidant capacity (TAC) of both solubilized and insoluble materials was measured at each step. Results showed that the overall TAC obtained by enzyme treatments was usually higher than that obtained by chemical extraction-based methods. In apple most of the TAC was released upon water washing and after pepsin treatment, whereas in spinach, beans, and whole wheat the TAC released by treatments with bacterial enzymes was prominent. Walnut had the highest TAC value, which was mainly released after pancreatin treatment. Therefore, the enzyme treatment is fundamental to estimate the overall potential TAC of foods having a high amount of polyphenols bound to dietary fiber or entrapped in the food matrix.

A SERS protocol as a potential tool to access 6-mercaptopurine release accelerated by glutathione-S-transferase.

PubMed

Wang, Ying; Sun, Jie; Yang, Qingran; Lu, Wenbo; Li, Yan; Dong, Jian; Qian, Weiping

2015-11-21

The developed method for monitoring GST, an important drug metabolic enzyme, could greatly facilitate researches on relative biological fields. In this work, we have developed a SERS technique to monitor the absorbance behaviour of 6-mercaptopurine (6-MP) and its glutathione-S-transferase (GST)-accelerated glutathione (GSH)-triggered release behaviour on the surface of gold nanoflowers (GNFs), using the GNFs as excellent SERS substrates. The SERS signal was used as an indicator of absorbance or release of 6-MP on the gold surface. We found that GST can accelerate GSH-triggered release behaviour of 6-MP from the gold surface. We speculated that GST catalyzes nucleophilic GSH to competitively bind with the electrophilic substance 6-MP. Experimental results have proved that the presented SERS protocol can be utilized as an effective tool for accessing the release of anticancer drugs.

32 CFR 93.3 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... SERVICE OF PROCESS; RELEASE OF OFFICIAL INFORMATION IN LITIGATION; AND TESTIMONY BY NSA PERSONNEL AS... testimony of NSA personnel as witnesses. (c) NSA personnel. (or NSA person) Includes present and former civilian employees of NSA (including non-appropriated fund activity employees), and present and former...

32 CFR 93.3 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... SERVICE OF PROCESS; RELEASE OF OFFICIAL INFORMATION IN LITIGATION; AND TESTIMONY BY NSA PERSONNEL AS... testimony of NSA personnel as witnesses. (c) NSA personnel. (or NSA person) Includes present and former civilian employees of NSA (including non-appropriated fund activity employees), and present and former...

32 CFR 93.3 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... SERVICE OF PROCESS; RELEASE OF OFFICIAL INFORMATION IN LITIGATION; AND TESTIMONY BY NSA PERSONNEL AS... testimony of NSA personnel as witnesses. (c) NSA personnel. (or NSA person) Includes present and former civilian employees of NSA (including non-appropriated fund activity employees), and present and former...

32 CFR 93.3 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... SERVICE OF PROCESS; RELEASE OF OFFICIAL INFORMATION IN LITIGATION; AND TESTIMONY BY NSA PERSONNEL AS... testimony of NSA personnel as witnesses. (c) NSA personnel. (or NSA person) Includes present and former civilian employees of NSA (including non-appropriated fund activity employees), and present and former...

32 CFR 93.3 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... SERVICE OF PROCESS; RELEASE OF OFFICIAL INFORMATION IN LITIGATION; AND TESTIMONY BY NSA PERSONNEL AS... testimony of NSA personnel as witnesses. (c) NSA personnel. (or NSA person) Includes present and former civilian employees of NSA (including non-appropriated fund activity employees), and present and former...

EPA Update on Gold King Mine Response Efforts for August 17, 2015

EPA Pesticide Factsheets

August 17th news release: EPA is committed to working closely with response agencies and state and local officials to ensure the safety of citizens, respond to concerns and to evaluate impact to water contaminated by the spill.

22 CFR 504. 3 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Relations BROADCASTING BOARD OF GOVERNORS TESTIMONY BY BBG EMPLOYEES, PRODUCTION OF OFFICIAL RECORDS, AND... or other competent authority for the production, disclosure, or release of records or for the... whatever method, for the production of records and information or for testimony which has not been ordered...

Government Censorship and Academic Freedom.

ERIC Educational Resources Information Center

Rosenbaum, Robert A.; And Others

1983-01-01

This third report in a series concerning restraints by government agencies on academic research concerns and recommends withdrawal of a recent presidential directive establishing a mechanism for controlling the release of classified information to the public through a system of prior review by government officials. (MSE)

Effect of Xenon Anesthesia Compared to Sevoflurane and Total Intravenous Anesthesia for Coronary Artery Bypass Graft Surgery on Postoperative Cardiac Troponin Release: An International, Multicenter, Phase 3, Single-blinded, Randomized Noninferiority Trial.

PubMed

Hofland, Jan; Ouattara, Alexandre; Fellahi, Jean-Luc; Gruenewald, Matthias; Hazebroucq, Jean; Ecoffey, Claude; Joseph, Pierre; Heringlake, Matthias; Steib, Annick; Coburn, Mark; Amour, Julien; Rozec, Bertrand; Liefde, Inge de; Meybohm, Patrick; Preckel, Benedikt; Hanouz, Jean-Luc; Tritapepe, Luigi; Tonner, Peter; Benhaoua, Hamina; Roesner, Jan Patrick; Bein, Berthold; Hanouz, Luc; Tenbrinck, Rob; Bogers, Ad J J C; Mik, Bert G; Coiffic, Alain; Renner, Jochen; Steinfath, Markus; Francksen, Helga; Broch, Ole; Haneya, Assad; Schaller, Manuella; Guinet, Patrick; Daviet, Lauren; Brianchon, Corinne; Rosier, Sebastien; Lehot, Jean-Jacques; Paarmann, Hauke; Schön, Julika; Hanke, Thorsten; Ettel, Joachym; Olsson, Silke; Klotz, Stefan; Samet, Amir; Laurinenas, Giedrius; Thibaud, Adrien; Cristinar, Mircea; Collanges, Olivier; Levy, François; Rossaint, Rolf; Stevanovic, Ana; Schaelte, Gereon; Stoppe, Christian; Hamou, Nora Ait; Hariri, Sarah; Quessard, Astrid; Carillion, Aude; Morin, Hélène; Silleran, Jacqueline; Robert, David; Crouzet, Anne-Sophie; Zacharowski, Kai; Reyher, Christian; Iken, Sonja; Weber, Nina C; Hollmann, Marcus; Eberl, Susanne; Carriero, Giovanni; Collacchi, Daria; Di Persio, Alessandra; Fourcade, Olivier; Bergt, Stefan; Alms, Angela

2017-12-01

Ischemic myocardial damage accompanying coronary artery bypass graft surgery remains a clinical challenge. We investigated whether xenon anesthesia could limit myocardial damage in coronary artery bypass graft surgery patients, as has been reported for animal ischemia models. In 17 university hospitals in France, Germany, Italy, and The Netherlands, low-risk elective, on-pump coronary artery bypass graft surgery patients were randomized to receive xenon, sevoflurane, or propofol-based total intravenous anesthesia for anesthesia maintenance. The primary outcome was the cardiac troponin I concentration in the blood 24 h postsurgery. The noninferiority margin for the mean difference in cardiac troponin I release between the xenon and sevoflurane groups was less than 0.15 ng/ml. Secondary outcomes were the safety and feasibility of xenon anesthesia. The first patient included at each center received xenon anesthesia for practical reasons. For all other patients, anesthesia maintenance was randomized (intention-to-treat: n = 492; per-protocol/without major protocol deviation: n = 446). Median 24-h postoperative cardiac troponin I concentrations (ng/ml [interquartile range]) were 1.14 [0.76 to 2.10] with xenon, 1.30 [0.78 to 2.67] with sevoflurane, and 1.48 [0.94 to 2.78] with total intravenous anesthesia [per-protocol]). The mean difference in cardiac troponin I release between xenon and sevoflurane was -0.09 ng/ml (95% CI, -0.30 to 0.11; per-protocol: P = 0.02). Postoperative cardiac troponin I release was significantly less with xenon than with total intravenous anesthesia (intention-to-treat: P = 0.05; per-protocol: P = 0.02). Perioperative variables and postoperative outcomes were comparable across all groups, with no safety concerns. In postoperative cardiac troponin I release, xenon was noninferior to sevoflurane in low-risk, on-pump coronary artery bypass graft surgery patients. Only with xenon was cardiac troponin I release less than with total intravenous anesthesia. Xenon anesthesia appeared safe and feasible.

43 CFR 11.70 - Quantification phase-general.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Section 11.70 Public Lands: Interior Office of the Secretary of the Interior NATURAL RESOURCE DAMAGE... or release on the injured natural resources for use in determining the appropriate amount of... Injury Determination phase, the authorized official shall quantify for each resource determined to be...

43 CFR 11.70 - Quantification phase-general.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Section 11.70 Public Lands: Interior Office of the Secretary of the Interior NATURAL RESOURCE DAMAGE... or release on the injured natural resources for use in determining the appropriate amount of... Injury Determination phase, the authorized official shall quantify for each resource determined to be...

5 CFR 2417.103 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... INFORMATION AND PRODUCTION OF OFFICIAL RECORDS IN LEGAL PROCEEDINGS General Provisions § 2417.103 Definitions... a court or other competent authority for the production, disclosure, or release of records or for... whatever method, for the production of records and information or for testimony which has not been ordered...

Overview of Preserve America

Science.gov Websites

Ground Project, New York; the Corinth and Alcorn County Mississippi Heritage Tourism Initiative heritage tourism programs. Since the program began in 2003, 843 communities have been designated as regional press releases; official notification of designation to state tourism offices and visitors bureaus

5 CFR 1305.2 - Production prohibited unless approved.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Production prohibited unless approved. 1305.2 Section 1305.2 Administrative Personnel OFFICE OF MANAGEMENT AND BUDGET ADMINISTRATIVE PROCEDURES RELEASE OF OFFICIAL INFORMATION, AND TESTIMONY BY OMB PERSONNEL AS WITNESSES, IN LITIGATION § 1305...

Release of the Biological Control Agent Puccinia jaceae var. solstitialis for Management of Yellow Starthistle at Fort Hunter Liggett, CA

DTIC Science & Technology

2010-07-01

used to manipulate the environment by burning, grazing, or revegetation efforts. Five insect species and a fungus have been officially released as...satisfied, the fungus would probably do extremely well and stress the plant early in the growing season. Used in conjunction with seed- feeding insects , it...241 km) south of San Francisco. The fort is primarily used as a training facility, where activities such as field maneuvers and live fire

Comparison of the ultrashort gonadotropin-releasing hormone agonist-antagonist protocol with microdose flare -up protocol in poor responders: a preliminary study.

PubMed

Berker, Bülent; Duvan, Candan İltemir; Kaya, Cemil; Aytaç, Ruşen; Satıroğlu, Hakan

2010-01-01

To determine the potential effect of the ultrashort gonadotropin-releasing hormone (GnRH) agonist/GnRH antagonist protocol versus the microdose GnRH agonist protocol in poor responders undergoing intracytoplasmic sperm injection (ICSI). The patients in the Agonist-Antagonist Group (n=41) were administered the ultrashort GnRH-agonist/ antagonist protocol, while the patients in the Microdose Group (n=41) were stimulated according to the microdose flare-up protocol. The mean number of mature oocytes retrieved was the primary outcome measure. Fertilization rate, implantation rate per embryo and clinical pregnancy rates were secondary outcome measures. There was no differenc between the mean number of mature oocytes retrieved in the two groups. There were also no statistical differences between the two groups in terms of peak serum E2 level, canceled cycles, endometrial thickness on hCG day, number of 2 pronucleus and number of embryos transferred. However, the total gonadotropin consumption and duration of stimulation were significantly higher with the Agonist-Antagonist Group compared with the Microdose Group. The implantation and clinical pregnancy rates were similar between the two groups. Despite the high dose of gonadotropin consumption and longer duration of stimulation with the ultrashort GnRH agonist/ antagonist protocol, it seems that the Agonist-Antagonist Protocol is not inferior to the microdose protocol in poor responders undergoing ICSI.

SURVIVAL OF CAPTIVE-REARED PUERTO RICAN PARROTS RELEASED IN THE CARIBBEAN NATIONAL FOREST

Treesearch

THOMAS H. WHITE; JAIME A. COLLAZO; FRANCISCO J. VILELLA

2005-01-01

We report first-year survival for 34 captive-reared Puerto Rican Parrots (Amazona vittata) released in the Caribbean National Forest, Puerto Rico between 2000 and 2002. The purpose of the releases were to increase population size and the potential number of breeding individuals of the sole extant wild population, and to refine release protocols for eventual...

Failure of antiarrhythmic drugs to prevent experimental reperfusion ventricular fibrillation.

PubMed

Naito, M; Michelson, E L; Kmetzo, J J; Kaplinsky, E; Dreifus, L S

1981-01-01

Ninety-nine adult mongrel dogs underwent acute ligation of the proximal left anterior descending coronary artery. Thirty minutes later, the occlusion was released to evaluate the effectiveness of five antiarrhythmic protocols in eliminating reperfusion ventricular fibrillation. The five protocols included: protocol 1 --i.v. lidocaine, preligation and prerelease (n = 19); protocol 2 -- i.v. lidocaine, prereperfusion only (n = 22); protocol 3 -- chronic, oral, daily amiodarone for 2 weeks preligation (n = 19); protocol 4 -- i.v. procainamide, preligation and prereperfusion (n = 21); and protocol 5 -- i.v. verapamil, prereperfusion (n = 18). Each regimen was evaluated with respect to the incidence of reperfusion ventricular fibrillation in dogs that survived to reperfusion, and the results were compared to 77 control dogs that underwent identical coronary artery occlusion and release procedures without drug therapy. The incidence of reperfusion ventricular fibrillation was as follows: protocol 1 -- seven of 15 dogs (47%); protocol 2 -- six of 18 (33%); protocol 3 -- 11 of 16 dogs (69%); protocol 4 -- eight of 17 dogs (47%); and protocol 5 -- 10 of 17 dogs (59%), compared with 36 of 60 (60%) in control dogs. Using chi-square analysis, protocol 2 was beneficial (p < 0.05). The dogs were then stratified into high- and low-risk subgroups based on the arrhythmic events of the antecedent coronary artery ligation periods, and predictive risk indexes for the occurrence of reperfusion ventricular fibrillation were developed. the Mantel-Haenszel method of statistical analysis revealed that none of these protocols resulted in a statistically significant reduction in the incidence of reperfusion ventricular fibrillation. Thus, use of these predictive indexes plus appropriate statistical methods has revealed, unexpectedly, limitations in the efficacy of a spectrum of antiarrhythmic agents in preventing reperfusion ventricular fibrillation.

32 CFR 93.1 - References.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 1 2013-07-01 2013-07-01 false References. 93.1 Section 93.1 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE PERSONNEL, MILITARY AND CIVILIAN ACCEPTANCE OF SERVICE OF PROCESS; RELEASE OF OFFICIAL INFORMATION IN LITIGATION; AND TESTIMONY BY NSA PERSONNEL AS...

32 CFR 93.4 - Policy.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 1 2012-07-01 2012-07-01 false Policy. 93.4 Section 93.4 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE PERSONNEL, MILITARY AND CIVILIAN ACCEPTANCE OF SERVICE OF PROCESS; RELEASE OF OFFICIAL INFORMATION IN LITIGATION; AND TESTIMONY BY NSA PERSONNEL AS...

32 CFR 93.1 - References.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 1 2012-07-01 2012-07-01 false References. 93.1 Section 93.1 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE PERSONNEL, MILITARY AND CIVILIAN ACCEPTANCE OF SERVICE OF PROCESS; RELEASE OF OFFICIAL INFORMATION IN LITIGATION; AND TESTIMONY BY NSA PERSONNEL AS...

32 CFR 93.4 - Policy.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 1 2011-07-01 2011-07-01 false Policy. 93.4 Section 93.4 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE PERSONNEL, MILITARY AND CIVILIAN ACCEPTANCE OF SERVICE OF PROCESS; RELEASE OF OFFICIAL INFORMATION IN LITIGATION; AND TESTIMONY BY NSA PERSONNEL AS...

32 CFR 93.4 - Policy.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 1 2014-07-01 2014-07-01 false Policy. 93.4 Section 93.4 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE PERSONNEL, MILITARY AND CIVILIAN ACCEPTANCE OF SERVICE OF PROCESS; RELEASE OF OFFICIAL INFORMATION IN LITIGATION; AND TESTIMONY BY NSA PERSONNEL AS...

32 CFR 93.4 - Policy.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 1 2010-07-01 2010-07-01 false Policy. 93.4 Section 93.4 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE PERSONNEL, MILITARY AND CIVILIAN ACCEPTANCE OF SERVICE OF PROCESS; RELEASE OF OFFICIAL INFORMATION IN LITIGATION; AND TESTIMONY BY NSA PERSONNEL AS...

32 CFR 93.1 - References.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 1 2014-07-01 2014-07-01 false References. 93.1 Section 93.1 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE PERSONNEL, MILITARY AND CIVILIAN ACCEPTANCE OF SERVICE OF PROCESS; RELEASE OF OFFICIAL INFORMATION IN LITIGATION; AND TESTIMONY BY NSA PERSONNEL AS...

32 CFR 93.1 - References.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 1 2010-07-01 2010-07-01 false References. 93.1 Section 93.1 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE PERSONNEL, MILITARY AND CIVILIAN ACCEPTANCE OF SERVICE OF PROCESS; RELEASE OF OFFICIAL INFORMATION IN LITIGATION; AND TESTIMONY BY NSA PERSONNEL AS...

32 CFR 93.1 - References.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 1 2011-07-01 2011-07-01 false References. 93.1 Section 93.1 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE PERSONNEL, MILITARY AND CIVILIAN ACCEPTANCE OF SERVICE OF PROCESS; RELEASE OF OFFICIAL INFORMATION IN LITIGATION; AND TESTIMONY BY NSA PERSONNEL AS...

32 CFR 93.4 - Policy.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 1 2013-07-01 2013-07-01 false Policy. 93.4 Section 93.4 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE PERSONNEL, MILITARY AND CIVILIAN ACCEPTANCE OF SERVICE OF PROCESS; RELEASE OF OFFICIAL INFORMATION IN LITIGATION; AND TESTIMONY BY NSA PERSONNEL AS...

39 CFR 265.3 - Responsibility.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 39 Postal Service 1 2013-07-01 2013-07-01 false Responsibility. 265.3 Section 265.3 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.3 Responsibility. (a) Custodian. Official records are in the custody of the postmaster or other head of a facility...

39 CFR 265.3 - Responsibility.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Responsibility. 265.3 Section 265.3 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.3 Responsibility. (a) Custodian. Official records are in the custody of the postmaster or other head of a facility...

39 CFR 265.3 - Responsibility.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 39 Postal Service 1 2014-07-01 2014-07-01 false Responsibility. 265.3 Section 265.3 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.3 Responsibility. (a) Custodian. Official records are in the custody of the postmaster or other head of a facility...

39 CFR 265.3 - Responsibility.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 39 Postal Service 1 2012-07-01 2012-07-01 false Responsibility. 265.3 Section 265.3 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.3 Responsibility. (a) Custodian. Official records are in the custody of the postmaster or other head of a facility...

39 CFR 265.3 - Responsibility.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 39 Postal Service 1 2011-07-01 2011-07-01 false Responsibility. 265.3 Section 265.3 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.3 Responsibility. (a) Custodian. Official records are in the custody of the postmaster or other head of a facility...

Protective Garments for Public Officials

DTIC Science & Technology

1973-08-01

Approved for public release; distribution urlimited. U. S. ARMY IAND WARFARE LABORATORY Aberdeen Proving Ground , Maryland 21005 ABSTRACT TThis task has...unlimited. - U. S. ARMY LAND WARFARE LABORATORY .&1 A~ereemProinaGroun~d. Morviarnd 21005 Aberden Pov\\J TECHNICAL REPORT NO. LW j<B0B73 PROTECTIVE

Framing the Framework: Discourses in Australia's National Values Education Policy

ERIC Educational Resources Information Center

Jones, Tiffany Mary

2009-01-01

In the past, many Australian state schools avoided teaching about values explicitly. However, the Australian government released Australia's first official values education policy in 2005: the "National Framework for Values Education in Australian Schools" (NFVEAS). This framework represents a local manifestation of the recent…

32 CFR 811.5 - Customers exempt from fees.

Code of Federal Regulations, 2011 CFR

2011-07-01

... National Defense Department of Defense (Continued) DEPARTMENT OF THE AIR FORCE SALES AND SERVICES RELEASE... for official activities. (c) VI records center materials or services furnished according to law or... activities contributing to an Air Force or DoD objective. (e) Nonprofit organizations for public health...

32 CFR 811.5 - Customers exempt from fees.

Code of Federal Regulations, 2012 CFR

2012-07-01

... National Defense Department of Defense (Continued) DEPARTMENT OF THE AIR FORCE SALES AND SERVICES RELEASE... for official activities. (c) VI records center materials or services furnished according to law or... activities contributing to an Air Force or DoD objective. (e) Nonprofit organizations for public health...

32 CFR 811.5 - Customers exempt from fees.

Code of Federal Regulations, 2013 CFR

2013-07-01

... National Defense Department of Defense (Continued) DEPARTMENT OF THE AIR FORCE SALES AND SERVICES RELEASE... for official activities. (c) VI records center materials or services furnished according to law or... activities contributing to an Air Force or DoD objective. (e) Nonprofit organizations for public health...

32 CFR 811.5 - Customers exempt from fees.

Code of Federal Regulations, 2014 CFR

2014-07-01

... National Defense Department of Defense (Continued) DEPARTMENT OF THE AIR FORCE SALES AND SERVICES RELEASE... for official activities. (c) VI records center materials or services furnished according to law or... activities contributing to an Air Force or DoD objective. (e) Nonprofit organizations for public health...

12 CFR 618.8300 - General regulation.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 6 2010-01-01 2010-01-01 false General regulation. 618.8300 Section 618.8300 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM GENERAL PROVISIONS Releasing Information § 618.8300 General regulation. Except as necessary in performing official duties or as authorized in the...

12 CFR 618.8300 - General regulation.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 6 2011-01-01 2011-01-01 false General regulation. 618.8300 Section 618.8300 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM GENERAL PROVISIONS Releasing Information § 618.8300 General regulation. Except as necessary in performing official duties or as authorized in the...

77 FR 56815 - Privacy Act of 1974; System of Records

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-14

... result in a contrary determination. Comments will be accepted on or before October 15, 2012. ADDRESSES... requests result in the creation of an Official Military Personnel File, containing Certificate of Release..., attitude about Army life, and measures of individual and organizational adjustments; test results from...

5 CFR 1305.1 - Purpose and scope.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Purpose and scope. 1305.1 Section 1305.1 Administrative Personnel OFFICE OF MANAGEMENT AND BUDGET ADMINISTRATIVE PROCEDURES RELEASE OF OFFICIAL... contains the regulations of the Office of Management and Budget (OMB) concerning procedures to be followed...

Novel analytical method to measure formaldehyde release from heated hair straightening cosmetic products: Impact on risk assessment.

PubMed

Galli, Corrado Lodovico; Bettin, Federico; Metra, Pierre; Fidente, Paola; De Dominicis, Emiliano; Marinovich, Marina

2015-08-01

Hair straightening cosmetic products may contain formaldehyde (FA). In Europe, FA is permitted for use in personal care products at concentrations ⩽ 0.2g/100g. According to the Cosmetic Ingredient Review (CIR) Expert Panel products are safe when formalin (a 37% saturated solution of FA in water) concentration does not exceed 0.2g/100g (0.074 g/100g calculated as FA). The official method of reference does not discriminate between "free" FA and FA released into the air after heating FA donors. The method presented here captures and collects the FA released into the air from heated cosmetic products by derivatization with 2,4-dinitrophenylhydrazine and final analysis by UPLC/DAD instrument. Reliable data in terms of linearity, recovery, repeatability and sensitivity are obtained. On a total of 72 market cosmetic products analyzed, 42% showed FA concentrations very close to or above the threshold value (0.074 g/100g calculated as FA) suggested by the Cosmetic Ingredient Review committee, whereas 11 products, negative using the official method of reference, were close to or above the threshold value (0.074 g/100g calculated as FA). This may pose a health problem for occasional users and professional hair stylists. Copyright © 2015 Elsevier Inc. All rights reserved.

BeetleBase in 2010: Revisions to Provide Comprehensive Genomic Information for Tribolium castaneum

USDA-ARS?s Scientific Manuscript database

BeetleBase (http://www.beetlebase.org) has been updated to provide more comprehensive genomic information for the red flour beetle Tribolium castaneum. The database contains genomic sequence scaffolds mapped to 10 linkage groups (genome assembly release Tcas_3.0), genetic linkage maps, the official ...

32 CFR 93.6 - Fees.

Code of Federal Regulations, 2014 CFR

2014-07-01

... SERVICE OF PROCESS; RELEASE OF OFFICIAL INFORMATION IN LITIGATION; AND TESTIMONY BY NSA PERSONNEL AS WITNESSES § 93.6 Fees. Consistent with the guidelines in § 93.1(e), NSA may charge reasonable fees to... providing such information, and may include: (a) The costs of time expended by NSA employees to process and...

32 CFR 93.6 - Fees.

Code of Federal Regulations, 2011 CFR

2011-07-01

... SERVICE OF PROCESS; RELEASE OF OFFICIAL INFORMATION IN LITIGATION; AND TESTIMONY BY NSA PERSONNEL AS WITNESSES § 93.6 Fees. Consistent with the guidelines in § 93.1(e), NSA may charge reasonable fees to... providing such information, and may include: (a) The costs of time expended by NSA employees to process and...

32 CFR 93.6 - Fees.

Code of Federal Regulations, 2013 CFR

2013-07-01

... SERVICE OF PROCESS; RELEASE OF OFFICIAL INFORMATION IN LITIGATION; AND TESTIMONY BY NSA PERSONNEL AS WITNESSES § 93.6 Fees. Consistent with the guidelines in § 93.1(e), NSA may charge reasonable fees to... providing such information, and may include: (a) The costs of time expended by NSA employees to process and...

32 CFR 93.6 - Fees.

Code of Federal Regulations, 2010 CFR

2010-07-01

... SERVICE OF PROCESS; RELEASE OF OFFICIAL INFORMATION IN LITIGATION; AND TESTIMONY BY NSA PERSONNEL AS WITNESSES § 93.6 Fees. Consistent with the guidelines in § 93.1(e), NSA may charge reasonable fees to... providing such information, and may include: (a) The costs of time expended by NSA employees to process and...

32 CFR 93.6 - Fees.

Code of Federal Regulations, 2012 CFR

2012-07-01

... SERVICE OF PROCESS; RELEASE OF OFFICIAL INFORMATION IN LITIGATION; AND TESTIMONY BY NSA PERSONNEL AS WITNESSES § 93.6 Fees. Consistent with the guidelines in § 93.1(e), NSA may charge reasonable fees to... providing such information, and may include: (a) The costs of time expended by NSA employees to process and...

75 FR 33355 - Records Schedules; Availability and Request for Comments

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-11

... of agency accomplishments, press releases, and files relating to educational campaigns. 6. Department... of Justice, Civil Division (N1-60-10-16, 1 item, 1 temporary item). Documents that are attorney... capacity based on actions they took in connection with their official position. 8. Department of Justice...

39 CFR 265.2 - Policy.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 39 Postal Service 1 2011-07-01 2011-07-01 false Policy. 265.2 Section 265.2 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.2 Policy. (a) It is the policy of the Postal Service to make its official records available to the public to the maximum...

39 CFR 265.2 - Policy.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Policy. 265.2 Section 265.2 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.2 Policy. (a) It is the policy of the Postal Service to make its official records available to the public to the maximum...

39 CFR 265.2 - Policy.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 39 Postal Service 1 2013-07-01 2013-07-01 false Policy. 265.2 Section 265.2 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.2 Policy. (a) It is the policy of the Postal Service to make its official records available to the public to the maximum...

39 CFR 265.2 - Policy.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 39 Postal Service 1 2012-07-01 2012-07-01 false Policy. 265.2 Section 265.2 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.2 Policy. (a) It is the policy of the Postal Service to make its official records available to the public to the maximum...

39 CFR 265.2 - Policy.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 39 Postal Service 1 2014-07-01 2014-07-01 false Policy. 265.2 Section 265.2 Postal Service UNITED STATES POSTAL SERVICE ORGANIZATION AND ADMINISTRATION RELEASE OF INFORMATION § 265.2 Policy. (a) It is the policy of the Postal Service to make its official records available to the public to the maximum...

40 CFR 264.1 - Purpose, scope and applicability.

Code of Federal Regulations, 2014 CFR

2014-07-01

... waste. (D) An immediate threat to human health, public safety, property, or the environment, from the... material or waste is necessary to protect human health or the environment, that official or specialist may..., a release of hazardous waste constituents to the environment, or a threat to human health. The owner...

32 CFR 725.4 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... employed by or on behalf of the DOD or on active duty with the United States Armed Forces (determining... 32 National Defense 5 2011-07-01 2011-07-01 false Definitions. 725.4 Section 725.4 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY PERSONNEL RELEASE OF OFFICIAL INFORMATION...

32 CFR 725.4 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... employed by or on behalf of the DOD or on active duty with the United States Armed Forces (determining... 32 National Defense 5 2010-07-01 2010-07-01 false Definitions. 725.4 Section 725.4 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY PERSONNEL RELEASE OF OFFICIAL INFORMATION...

Let's Weigh in on "Deflategate"

ERIC Educational Resources Information Center

Toepker, Terrence

2016-01-01

The September 2015 paper "Bouncing Back from 'Deflategate'" is a very interesting article from a physics viewpoint. However, we doubt that the National Football League (NFL) officials will bounce footballs and measure the coefficient of restitution to verify that the footballs remain properly inflated. The release of a few pounds per…

32 CFR 725.2 - Policy.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 5 2012-07-01 2012-07-01 false Policy. 725.2 Section 725.2 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY PERSONNEL RELEASE OF OFFICIAL INFORMATION FOR LITIGATION PURPOSES AND TESTIMONY BY DEPARTMENT OF THE NAVY PERSONNEL § 725.2 Policy. (a) It is DON policy...

78 FR 68502 - Notice of Open Public Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-14

... U.S.-CHINA ECONOMIC AND SECURITY REVIEW COMMISSION Notice of Open Public Meeting AGENCY: U.S.-China Economic and Security Review Commission. ACTION: Notice of Official Public Release of the... recommendations of its 2013 Annual Report to Congress are open to the public. Topics To Be Discussed The...

48 CFR 952.204-75 - Public affairs.

Code of Federal Regulations, 2014 CFR

2014-10-01

... cooperate with the Department in releasing unclassified information to the public and news media regarding... information to the public and news media are coordinated through, and approved by, a management official at an... may attract regional or national news media attention and of non-routine inquiries from national news...

48 CFR 952.204-75 - Public affairs.

Code of Federal Regulations, 2013 CFR

2013-10-01

... cooperate with the Department in releasing unclassified information to the public and news media regarding... information to the public and news media are coordinated through, and approved by, a management official at an... may attract regional or national news media attention and of non-routine inquiries from national news...

48 CFR 952.204-75 - Public affairs.

Code of Federal Regulations, 2012 CFR

2012-10-01

... cooperate with the Department in releasing unclassified information to the public and news media regarding... information to the public and news media are coordinated through, and approved by, a management official at an... may attract regional or national news media attention and of non-routine inquiries from national news...

32 CFR 705.8 - Motion pictures.

Code of Federal Regulations, 2010 CFR

2010-07-01

... OFFICIAL RECORDS PUBLIC AFFAIRS REGULATIONS § 705.8 Motion pictures. (a) The rules and procedures given in... Defense (Public Affairs) for clearance for public release. They will be accompained by five copies of the... Assistant Secretary of Defense (Public Affairs). [41 FR 29101, July 15, 1976, as amended at 44 FR 6390, Feb...

Democrats Seek Education Department "Recovery Czar"

ERIC Educational Resources Information Center

Davis, Michelle R.

2006-01-01

As congressional Democrats declared last week that federal efforts to help Gulf Coast schools with hurricane recovery aren't working, school officials from the region hit by Hurricanes Katrina and Rita last year urged lawmakers to provide more regulatory flexibility and more money. On April 26, 2006, House Democrats released a report criticizing…

20 CFR 702.113 - Inspection of records of the OWCP.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Provisions Records § 702.113 Inspection of records of the OWCP. Any party in interest may be permitted to examine the record of the case in which he is interested. The official custodian of the record sought to... provisions concerning release of information regarding injured employees undergoing vocational rehabilitation...

5 CFR 1305.5 - No private right of action.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false No private right of action. 1305.5 Section 1305.5 Administrative Personnel OFFICE OF MANAGEMENT AND BUDGET ADMINISTRATIVE PROCEDURES RELEASE OF OFFICIAL INFORMATION, AND TESTIMONY BY OMB PERSONNEL AS WITNESSES, IN LITIGATION § 1305.5 No...

Counterfeit Version of Botox Found in the United States

MedlinePlus

... fax, or by phone. Health care professionals and consumers can either: Complete and submit the report online: www.fda.gov/MedWatch/report.htm , or ... Continuing Education Inspections & Compliance Federal, State & Local Officials ... Content Home Latest Recalls Report an Adverse Event MedWatch Safety Alerts News Releases ...

32 CFR 516.48 - Official information.

Code of Federal Regulations, 2011 CFR

2011-07-01

... witness in court provided such interview or appearance is consistent with the requirements of §§ 516.49... should be present during any interview or testimony to act as legal representative of the Army. If a question seeks information not previously authorized for release, the legal representative will advise the...

32 CFR 516.48 - Official information.

Code of Federal Regulations, 2010 CFR

2010-07-01

... witness in court provided such interview or appearance is consistent with the requirements of §§ 516.49... should be present during any interview or testimony to act as legal representative of the Army. If a question seeks information not previously authorized for release, the legal representative will advise the...

Impact of leaching conditions on constituents release from Flue Gas Desulfurization Gypsum (FGDG) and FGDG-soil mixture.

PubMed

Koralegedara, N H; Al-Abed, S R; Arambewela, M K J; Dionysiou, D D

2017-02-15

The interest in using Flue Gas Desulfurization Gypsum (FGDG) for land applications has increased recently. This study evaluates the leaching characteristics of trace elements in "modern" FGDG (produced after fly ash removal) and FGDG-mixed soil (SF) under different environmental conditions using recently approved EPA leaching methods (1313-1316). These methods employ various pH and liquid-solid (LS) ratios under batch leaching, column percolation and diffusion controlled release scenarios. Toxicity Characteristic Leaching Protocol (TCLP) and Synthetic Precipitation Leaching Protocol (SPLP) were used for comparison. The data obtained from new EPA methods provide broad insight into constituent release from FGDG and SF when compared to TCLP and SPLP. The release of toxic elements such as Hg, As, Pb, Co, Cd and Cr from SF was negligible. High release of B from FGDG was observed under all tested conditions; however, its release from SF was low. Both FGDG and SF released Se under all pH conditions (2-13) and LS ratios (1-10) in low concentrations (0.02-0.2mg/L). The data from this study could be used to investigate potential use of "modern" FGDG for new beneficial land applications. Published by Elsevier B.V.

Management Strategies to Facilitate Optimal Outcomes for Patients Treated with Delayed-release Dimethyl Fumarate.

PubMed

Mayer, Lori; Fink, Mary Kay; Sammarco, Carrie; Laing, Lisa

2018-04-01

Delayed-release dimethyl fumarate is an oral disease-modifying therapy that has demonstrated significant efficacy in adults with relapsing-remitting multiple sclerosis. Incidences of flushing and gastrointestinal adverse events are common in the first month after delayed-release dimethyl fumarate initiation. Our objective was to propose mitigation strategies for adverse events related to initiation of delayed-release dimethyl fumarate in the treatment of patients with multiple sclerosis. Studies of individually developed mitigation strategies and chart reviews were evaluated. Those results, as well as mitigation protocols developed at multiple sclerosis care centers, are summarized. Key steps to optimize the effectiveness of delayed-release dimethyl fumarate treatment include education prior to and at the time of delayed-release dimethyl fumarate initiation, initiation dose protocol gradually increasing to maintenance dose, dietary suggestions for co-administration with food, gastrointestinal symptom management with over-the-counter medications, flushing symptom management with aspirin, and temporary dose reduction. Using the available evidence from clinical trials and evaluations of post-marketing studies, these strategies to manage gastrointestinal and flushing symptoms can be effective and helpful to the patient when initiating delayed-release dimethyl fumarate.

Validation of the Italian version of the Movement Disorder Society--Unified Parkinson's Disease Rating Scale.

PubMed

Antonini, Angelo; Abbruzzese, Giovanni; Ferini-Strambi, Luigi; Tilley, Barbara; Huang, Jing; Stebbins, Glenn T; Goetz, Christopher G; Barone, Paolo; Bandettini di Poggio, Monica; Fabbrini, Giovanni; Di Stasio, Flavio; Tinazzi, Michele; Bovi, Tommaso; Ramat, Silvia; Meoni, Sara; Pezzoli, Gianni; Canesi, Margherita; Martinelli, Paolo; Maria Scaglione, Cesa Lorella; Rossi, Aroldo; Tambasco, Nicola; Santangelo, Gabriella; Picillo, Marina; Morgante, Letterio; Morgante, Francesca; Quatrale, Rocco; Sensi, MariaChiara; Pilleri, Manuela; Biundo, Roberta; Nordera, Giampietro; Caria, Antonella; Pacchetti, Claudio; Zangaglia, Roberta; Lopiano, Leonardo; Zibetti, Maurizio; Zappia, Mario; Nicoletti, Alessandra; Quattrone, Aldo; Salsone, Maria; Cossu, Gianni; Murgia, Daniela; Albanese, Alberto; Del Sorbo, Francesca

2013-05-01

The Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS) has been available in English since 2008. As part of this process, the MDS-UPDRS organizing team developed guidelines for development of official non-English translations. We present here the formal process for completing officially approved non-English versions of the MDS-UPDRS and specifically focus on the first of these versions in Italian. The MDS-UPDRS was translated into Italian and tested in 377 native-Italian speaking PD patients. Confirmatory and exploratory factor analyses determined whether the factor structure for the English-language MDS-UPDRS could be confirmed in data collected using the Italian translation. To be designated an 'Official MDS translation,' the Comparative Fit Index (CFI) had to be ≥0.90 relative to the English-language version. For all four parts of the Italian MDS-UPDRS, the CFI, in comparison with the English-language data, was ≥0.94. Exploratory factor analyses revealed some differences between the two datasets, however these differences were considered to be within an acceptable range. The Italian version of the MDS-UPDRS reaches the criterion to be designated as an Official Translation and is now available for use. This protocol will serve as outline for further validation of this in multiple languages.

Facile MALDI-MS analysis of neutral glycans in NaOH-doped matrixes: microwave-assisted deglycosylation and one-step purification with diamond nanoparticles.

PubMed

Tzeng, Yan-Kai; Chang, Cheng-Chun; Huang, Chien-Ning; Wu, Chih-Che; Han, Chau-Chung; Chang, Huan-Cheng

2008-09-01

A streamlined protocol has been developed to accelerate, simplify, and enhance matrix-assisted laser desorption/ionization (MALDI) time-of-flight (TOF) mass spectrometry (MS) of neutral underivatized glycans released from glycoproteins. It involved microwave-assisted enzymatic digestion and release of glycans, followed by rapid removal of proteins and peptides with carboxylated/oxidized diamond nanoparticles, and finally treating the analytes with NaOH before mixing them with acidic matrix (such as 2,5-dihydroxybenzoic acid) to suppress the formation of both peptide and potassiated oligosaccharide ions in MS analysis. The advantages of this protocol were demonstrated with MALDI-TOF-MS of N-linked glycans released from ovalbumin and ribonuclease B.

JPRS Report, China

DTIC Science & Technology

1990-01-08

Wash- ington in the middle of the presidential race between Bush and Dukakis, Deng Xiaoping violated diplomatic protocol by telling U.S. officials...explanation for their evil acts and failed to prevent some of his subordinates from publicly breaking with the CPC authorities and seeking political...want to guide the masses of workers toward the road of reform and the road of labor-capital cooperation to prevent them from developing revolutionary

The International Nexus Between Drugs and Terror: Lessons in Conflict and Diplomacy

DTIC Science & Technology

2010-12-01

claimed the intelligence recovered provided evidentiary documentation that there were verifiable links between the governments of both Ecuador and...not reflect the official policy or position of the Department of Defense or the U.S. Government . IRB Protocol number: N/A. 12a. DISTRIBUTION...Revolucionarias de Colombia) FBI Federal Bureau of Investigation GAO Government Accountability Office HRK Kurdistan Freedom Brigade (Hazen Rizgariya Kurdistan

Branched Nerve Allografts to Improve Outcomes in Facial Composite Tissue Transplantation

DTIC Science & Technology

2017-12-01

Ethicon, Inc. Somervile, N.J.). Postoperatively, animals were recovered per standard protocol in the animal care facility.  Experimental Design ...official Department of the Army position, policy or decision unless so designated by other documentation. REPORT DOCUMENTATION PAGE Form Approved OMB No...a human xenograft with or without oral Tacrolimus. Electrophysiologic assessments were performed pre -operatively and at the study endpoint (24 weeks

Comparison of the ultrashort gonadotropin-releasing hormone agonist-antagonist protocol with microdose flare -up protocol in poor responders: a preliminary study

PubMed Central

Berker, Bülent; Duvan, Candan İltemir; Kaya, Cemil; Aytaç, Ruşen; Şatıroğlu, Hakan

2010-01-01

Objective To determine the potential effect of the ultrashort gonadotropin-releasing hormone (GnRH) agonist/GnRH antagonist protocol versus the microdose GnRH agonist protocol in poor responders undergoing intracytoplasmic sperm injection (ICSI). Material and Methods The patients in the Agonist-Antagonist Group (n=41) were administered the ultrashort GnRH-agonist/ antagonist protocol, while the patients in the Microdose Group (n=41) were stimulated according to the microdose flare-up protocol. The mean number of mature oocytes retrieved was the primary outcome measure. Fertilization rate, implantation rate per embryo and clinical pregnancy rates were secondary outcome measures. Results There was no differenc between the mean number of mature oocytes retrieved in the two groups. There were also no statistical differences between the two groups in terms of peak serum E2 level, canceled cycles, endometrial thickness on hCG day, number of 2 pronucleus and number of embryos transferred. However, the total gonadotropin consumption and duration of stimulation were significantly higher with the Agonist-Antagonist Group compared with the Microdose Group. The implantation and clinical pregnancy rates were similar between the two groups. Conclusion Despite the high dose of gonadotropin consumption and longer duration of stimulation with the ultrashort GnRH agonist/ antagonist protocol, it seems that the Agonist-Antagonist Protocol is not inferior to the microdose protocol in poor responders undergoing ICSI. PMID:24591934

Fabrication of monodispersive nanoscale alginate-chitosan core-shell particulate systems for controlled release studies

NASA Astrophysics Data System (ADS)

Körpe, Didem Aksoy; Malekghasemi, Soheil; Aydın, Uğur; Duman, Memed

2014-12-01

Biopolymers such as chitosan and alginate are widely used for controlled drug delivery systems. The present work aimed to develop a new protocol for preparation of monodisperse alginate-coated chitosan nanoparticles at nanoscale. Modifications of preparation protocol contain changing the pH of polymer solutions and adding extra centrifugation steps into the procedure. While chitosan nanoparticles were synthesized by ionic gelation method, they were coated with alginate by electrostatic interaction. The size, morphology, charge, and structural characterization of prepared core-shell nanoparticulated system were performed by AFM, Zeta sizer, and FTIR. BSA and DOX were loaded as test biomolecules to core and shell part of the nanoparticle, respectively. Release profiles of BSA and DOX were determined by spectrophotometry. The sizes of both chitosan and alginate-coated chitosan nanoparticles which were prepared by modified protocol were measured to be 50 ± 10 and 60 ± 3 nm, respectively. After loading BSA and DOX, the average size of the particles increased to 80 ± 7 nm. Moreover, while the zeta potential of chitosan nanoparticles was positive value, the value was inverted to negative after alginate coating. Release profile measurements of BSA and DOX were determined during 57 and 2 days, respectively. Our results demonstrated that monodisperse alginate-coated nanoparticles were synthesized and loaded successfully using our modified protocol.

Ambitious U.S. Federal Budget Proposal Strong on Science, Short on Details

NASA Astrophysics Data System (ADS)

Showstack, Randy

2009-03-01

The proposed $3.6 trillion U.S. federal budget for fiscal year (FY) 2010, which the Obama administration released on 26 February, includes significant funding for federal science agencies. The budget also emphasizes the development of a comprehensive energy and climate change plan-including a cap and trade program to reduce greenhouse gas emissions-``to transform our energy supply and slow global warming,'' according to the budget document released by the White House Office of Management and Budget (OMB). However, the 134-page budget document-which also emphasizes a theme of rebuilding environmental and resource agencies-is thin on specifics. Programmatic budget details will be released in April, according to an OMB senior official.

Two Decades into the LCR: What We Do and Still Don’t Know to Solve Lead Problems

EPA Science Inventory

Site selection and sampling protocol biases in LCR samplingunderestimate peak lead and copper concentrations whilemissing erratic lead release episodes resulting from distributionsystem chemical and physical disturbances. Possible sitetargeting and sampling protocol changes could...

Two Decades into the LCR: What We Do and Still Don’t Know to Solve Lead Problems - abstract

EPA Science Inventory

Site selection and sampling protocol biases in LCR samplingunderestimate peak lead and copper concentrations whilemissing erratic lead release episodes resulting from distributionsystem chemical and physical disturbances. Possible sitetargeting and sampling protocol changes could...

Improved coverage of cDNA-AFLP by sequential digestion of immobilized cDNA.

PubMed

Weiberg, Arne; Pöhler, Dirk; Morgenstern, Burkhard; Karlovsky, Petr

2008-10-13

cDNA-AFLP is a transcriptomics technique which does not require prior sequence information and can therefore be used as a gene discovery tool. The method is based on selective amplification of cDNA fragments generated by restriction endonucleases, electrophoretic separation of the products and comparison of the band patterns between treated samples and controls. Unequal distribution of restriction sites used to generate cDNA fragments negatively affects the performance of cDNA-AFLP. Some transcripts are represented by more than one fragment while other escape detection, causing redundancy and reducing the coverage of the analysis, respectively. With the goal of improving the coverage of cDNA-AFLP without increasing its redundancy, we designed a modified cDNA-AFLP protocol. Immobilized cDNA is sequentially digested with several restriction endonucleases and the released DNA fragments are collected in mutually exclusive pools. To investigate the performance of the protocol, software tool MECS (Multiple Enzyme cDNA-AFLP Simulation) was written in Perl. cDNA-AFLP protocols described in the literature and the new sequential digestion protocol were simulated on sets of cDNA sequences from mouse, human and Arabidopsis thaliana. The redundancy and coverage, the total number of PCR reactions, and the average fragment length were calculated for each protocol and cDNA set. Simulation revealed that sequential digestion of immobilized cDNA followed by the partitioning of released fragments into mutually exclusive pools outperformed other cDNA-AFLP protocols in terms of coverage, redundancy, fragment length, and the total number of PCRs. Primers generating 30 to 70 amplicons per PCR provided the highest fraction of electrophoretically distinguishable fragments suitable for normalization. For A. thaliana, human and mice transcriptome, the use of two marking enzymes and three sequentially applied releasing enzymes for each of the marking enzymes is recommended.

40 CFR 310.21 - How does EPA resolve disputes?

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 28 2011-07-01 2011-07-01 false How does EPA resolve disputes? 310.21... HAZARDOUS SUBSTANCE RELEASES Provisions How to Get Reimbursed § 310.21 How does EPA resolve disputes? (a) The EPA reimbursement official's decision is final EPA action unless you file a request for review by...

78 FR 54713 - Self-Regulatory Organizations; ICE Clear Europe Limited; Notice of Filing and Immediate...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-05

... Regulations or other official interpretations thereunder (collectively ``FATCA''). II. Self-Regulatory... changes allow ICE Clear Europe to be in compliance with FATCA Regulations. \\8\\ 15 U.S.C. 78q-1. B. Self... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-70283; File No. SR-ICEEU-2013-08] Self...

Identification of volatiles released by diapausing brown marmorated stink bugs, Halyomorpha halys (Hemiptera: Pentatomidae)

USDA-ARS?s Scientific Manuscript database

The brown marmorated stink bug (BMSB), Halyomorpha halys, is an agricultural and urban pest that has become widely established as an invasive species of major concern. This species forms large aggregations when entering diapause, and it is often these aggregations that are found by officials conduc...

46 CFR 204.5 - Notification to claimant of action on claim.

Code of Federal Regulations, 2011 CFR

2011-10-01

... releasing the United States, its agents and employees from all further claims relating to the incident giving rise to the approved claim. (b) If the claim is finally denied, the official vested with such... with the action may institute suit against the United States not later than six months after the date...

32 CFR Appendix A to Part 295 - For Official Use Only (FOUO)

Code of Federal Regulations, 2010 CFR

2010-07-01

... governmental interest will be jeopardized by its release. C. Historical Papers Records such as notes, working papers, and drafts retained as historical evidence of actions enjoy no special status apart from the... “FOUO” before the beginning of the text. Such messages shall be transmitted in accordance with...

14 CFR 1214.607 - Media and public inquiries.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 5 2013-01-01 2013-01-01 false Media and public inquiries. 1214.607... Aboard Space Shuttle Flights § 1214.607 Media and public inquiries. (a) Official Flight Kit. Information on the contents of OFK's will be routinely released to the media and to the public upon their request...

14 CFR 1214.607 - Media and public inquiries.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Media and public inquiries. 1214.607... Aboard Space Shuttle Flights § 1214.607 Media and public inquiries. (a) Official Flight Kit. Information on the contents of OFK's will be routinely released to the media and to the public upon their request...

14 CFR 1214.607 - Media and public inquiries.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Media and public inquiries. 1214.607... Aboard Space Shuttle Flights § 1214.607 Media and public inquiries. (a) Official Flight Kit. Information on the contents of OFK's will be routinely released to the media and to the public upon their request...

14 CFR 1214.607 - Media and public inquiries.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Media and public inquiries. 1214.607 Section... Aboard Space Shuttle Flights § 1214.607 Media and public inquiries. (a) Official Flight Kit. Information on the contents of OFK's will be routinely released to the media and to the public upon their request...

7 CFR 1280.631 - Results of the referendum.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 10 2013-01-01 2013-01-01 false Results of the referendum. 1280.631 Section 1280.631... INFORMATION ORDER Procedures To Request a Referendum Definitions § 1280.631 Results of the referendum. (a) The... Administrator, AMS, shall tabulate the results of the ballots. USDA will issue an official press release...

7 CFR 1280.631 - Results of the referendum.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false Results of the referendum. 1280.631 Section 1280.631... INFORMATION ORDER Procedures To Request a Referendum Definitions § 1280.631 Results of the referendum. (a) The... Administrator, AMS, shall tabulate the results of the ballots. USDA will issue an official press release...

7 CFR 1280.631 - Results of the referendum.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 10 2011-01-01 2011-01-01 false Results of the referendum. 1280.631 Section 1280.631... INFORMATION ORDER Procedures To Request a Referendum Definitions § 1280.631 Results of the referendum. (a) The... Administrator, AMS, shall tabulate the results of the ballots. USDA will issue an official press release...

7 CFR 1280.631 - Results of the referendum.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 10 2014-01-01 2014-01-01 false Results of the referendum. 1280.631 Section 1280.631... INFORMATION ORDER Procedures To Request a Referendum Definitions § 1280.631 Results of the referendum. (a) The... Administrator, AMS, shall tabulate the results of the ballots. USDA will issue an official press release...

7 CFR 1280.631 - Results of the referendum.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 10 2012-01-01 2012-01-01 false Results of the referendum. 1280.631 Section 1280.631... INFORMATION ORDER Procedures To Request a Referendum Definitions § 1280.631 Results of the referendum. (a) The... Administrator, AMS, shall tabulate the results of the ballots. USDA will issue an official press release...

Truhart-NR, A Root-knot Nematode Resistant, Pimento-type Pepper Cultivar

USDA-ARS?s Scientific Manuscript database

Efforts to develop a high-yielding, pimento-type pepper (Capsicum annuum L.) cultivar that is highly resistant to root-knot nematodes were completed with the official release of Truhart-NR on October 20, 2009. The new cultivar is homozygous for the dominant N gene that conditions a high level of re...

‘Truhart-NR’, A Root-knot Nematode Resistant, Pimento-type Pepper

USDA-ARS?s Scientific Manuscript database

Efforts to develop a high-yielding, pimento-type pepper (Capsicum annuum L.) cultivar that is highly resistant to root-knot nematodes were completed with the official release of Truhart-NR on October 20, 2009. The new cultivar is homozygous for the dominant N gene that conditions a high level of re...

OIG News Release: Former EPA official sentenced to 32 months in prison for defrauding government under ‘CIA agent’ guise

EPA Pesticide Factsheets

WASHINGTON – John C. Beale, a former employee of the EPA, today was sentenced to 32 months in prison following a plea agreement in which he admitted perpetrating multiple frauds under the bogus guise of performing undercover work as a CIA agent.

How One State Established School Library/Technology Standards

ERIC Educational Resources Information Center

Bartow, Colet

2009-01-01

Educational standards continue to be hot topics of discussion for this year and, no doubt, beyond. The Council of Chief State School Officials (CCSSO) and the National Governors' Association Center for Best Practices (NGA Center) has initiated a study based on "Common Core" English/Language Arts and Mathematics Standards. The release of…

76 FR 59034 - Access by Historical Researchers and Certain Former Government Personnel

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-23

...) Director, Information Management Services means the Senior Agency Official as defined in Section 6.1(mm) of... communicated or documentary material, regardless of its physical form that is owned by, produced by or for, or..., Information Review and Release Group, Information Management Services, and composed of the Information Review...

Never-Ending Learning

DTIC Science & Technology

2010-08-01

they begin or end an instance. The learned model uses part-of-speech features to identify typical music group names (e.g., The Beatles , The Ramones...APPROVED FOR PUBLIC RELEASE; DISTRIBUTION UNLIMITED. STINFO COPY The views and...conclusions contained in this document are those of the authors and should not be interpreted as necessarily representing the official policies, either

32 CFR 705.6 - Releasing public information material to the media.

Code of Federal Regulations, 2011 CFR

2011-07-01

... for questions without specific subject matter in mind, but the press should be clearly informed of the... should be present. (iv) Official spokesmen will be prepared to answer questions in a frank and candid... questions in advance. If this is considered advisable, as in cases where highly technical answers may be...

32 CFR 705.6 - Releasing public information material to the media.

Code of Federal Regulations, 2010 CFR

2010-07-01

... for questions without specific subject matter in mind, but the press should be clearly informed of the... should be present. (iv) Official spokesmen will be prepared to answer questions in a frank and candid... questions in advance. If this is considered advisable, as in cases where highly technical answers may be...

Clinical and diagnostic developments of a gamma interferon release assay for use in bovine tuberculosis control programs

USDA-ARS?s Scientific Manuscript database

Currently the Bovigam assay is used as an official supplemental test within the bovine tuberculosis eradication program. This assay measures interferon-gamma (IFN-gamma) produced by lymphocytes in response to specific antigens. The objectives of the present study were to evaluate two Mycobacterium ...

An efficient MPI/OpenMP parallelization of the Hartree–Fock–Roothaan method for the first generation of Intel® Xeon Phi™ processor architecture

DOE PAGES

Mironov, Vladimir; Moskovsky, Alexander; D’Mello, Michael; ...

2017-10-04

The Hartree-Fock (HF) method in the quantum chemistry package GAMESS represents one of the most irregular algorithms in computation today. Major steps in the calculation are the irregular computation of electron repulsion integrals (ERIs) and the building of the Fock matrix. These are the central components of the main Self Consistent Field (SCF) loop, the key hotspot in Electronic Structure (ES) codes. By threading the MPI ranks in the official release of the GAMESS code, we not only speed up the main SCF loop (4x to 6x for large systems), but also achieve a significant (>2x) reduction in the overallmore » memory footprint. These improvements are a direct consequence of memory access optimizations within the MPI ranks. We benchmark our implementation against the official release of the GAMESS code on the Intel R Xeon PhiTM supercomputer. Here, scaling numbers are reported on up to 7,680 cores on Intel Xeon Phi coprocessors.« less

Coordinated Response to Reports of Possible Anthrax Contamination, Idaho, 2001

PubMed Central

Hudson, Richard; Barnes, Shana; Hahn, Christine

2002-01-01

In 2001, the intentional release of anthrax spores in the eastern United States increased concern about exposure to anthrax nationwide, and residents of Idaho sought assistance. Response from state and local agencies was required, increasing the strain on epidemiologists, laboratorians, and communications personnel. In late 2001, Idaho’s public health communications system handled 133 calls about suspicious powders. For each call, a multiagency bridge call was established, and participants (public health officials, epidemiologists, police, Federal Bureau of Investigation personnel, hazardous materials officials, and others) determined which samples would be tested by the state public health laboratory. A triage system for calls helped relieve the burden on public safety and health systems. PMID:12396922

Prevention of Post-Traumatic Epilepsy by Transcranial Direct Current Stimulation

DTIC Science & Technology

2014-09-01

epidural fluid percussion itself. As an improvement on the classic LFPI procedure, we designed and validated a new protocol, termed rapid fluid ...plated on an 8X8 micoelectrode array (left) and bathed in oxygenated artificial cerebrospinal fluid . Cortical excitability was measured as the magnitude...not be construed as an official Department of the Army position, policy or decision unless so designated by other documentation. 1 REPORT

Illicit Networks: Targeting the Nexus Between Terrorists, Proliferators, and Narcotraffickers

DTIC Science & Technology

2010-12-01

the official policy or position of the Department of Defense or the U.S. government . IRB Protocol number: N/A 12a. DISTRIBUTION / AVAILABILITY...national and international security. These illicit networks exist within the shadows of legitimate trade and governance . They exploit an abundant...Current U.S. government efforts to counter these activities are similarly “stovepiped,” The term “cylinders of excellence” has been used to describe

Technical note: enumeration of mesophilic aerobes in milk: evaluation of standard official protocols and Petrifilm aerobic count plates.

PubMed

Freitas, R; Nero, L A; Carvalho, A F

2009-07-01

Enumeration of mesophilic aerobes (MA) is the main quality and hygiene parameter for raw and pasteurized milk. High levels of these microorganisms indicate poor conditions in production, storage, and processing of milk, and also the presence of pathogens. Fifteen raw and 15 pasteurized milk samples were submitted for MA enumeration by a conventional plating method (using plate count agar) and Petrifilm Aerobic Count plates (3M, St. Paul, MN), followed by incubation according to 3 official protocols: IDF/ISO (incubation at 30 degrees C for 72 h), American Public Health Association (32 degrees C for 48 h), and Brazilian Ministry of Agriculture (36 degrees C for 48 h). The results were compared by linear regression and ANOVA. Considering the results from conventional methodology, good correlation indices and absence of significant differences between mean counts were observed, independent of type of milk sample (raw or pasteurized) and incubation conditions (IDF/ISO, American Public Health Association, or Ministry of Agriculture). Considering the results from Petrifilm Aerobic Count plates, good correlation indices and absence of significant differences were only observed for raw milk samples. The microbiota of pasteurized milk interfered negatively with the performance of Petrifilm Aerobic Count plates, probably because of the presence of microorganisms that poorly reduce the dye indicator of this system.

Confronting the HIV, Tuberculosis, Addiction, and Incarceration Syndemic in Southeast Asia: Lessons Learned from Malaysia.

PubMed

Culbert, Gabriel J; Pillai, Veena; Bick, Joseph; Al-Darraji, Haider A; Wickersham, Jeffrey A; Wegman, Martin P; Bazazi, Alexander R; Ferro, Enrico; Copenhaver, Michael; Kamarulzaman, Adeeba; Altice, Frederick L

2016-09-01

Throughout Southeast Asia, repressive drug laws have resulted in high rates of imprisonment in people who inject drugs (PWID) and people living with HIV (PLH), greatly magnifying the harm associated with HIV, tuberculosis, and addiction. We review findings from Malaysia's largest prison to describe the negative synergistic effects of HIV, tuberculosis, addiction, and incarceration that contribute to a 'perfect storm' of events challenging public and personal health and offer insights into innovative strategies to control these converging epidemics. The majority of PLH who are imprisoned in Malaysia are opioid dependent PWID. Although promoted by official policy, evidence-based addiction treatment is largely unavailable, contributing to rapid relapse and/or overdose after release. Similarly, HIV treatment in prisons and compulsory drug treatment centers is sometimes inadequate or absent. The prevalence of active tuberculosis is high, particularly in PLH, and over 80 % of prisoners and prison personnel are latently infected. Mandatory HIV testing and subsequent segregation of HIV-infected prisoners increases the likelihood of tuberculosis acquisition and progression to active disease, amplifying the reservoir of infection for other prisoners. We discuss strategies to control these intersecting epidemics including screening linked to standardized treatment protocols for all three conditions, and effective transitional programs for released prisoners. For example, recently introduced evidence-based interventions in prisons like antiretroviral therapy (ART) to treat HIV, isoniazid preventive therapy to treat latent tuberculosis infection, and methadone maintenance to treat opioid dependence, have markedly improved clinical care and reduced morbidity and mortality. Since introduction of these interventions in September 2012, all-cause and HIV-related mortality have decreased by 50.0 % and 75.7 %, respectively. We discuss the further deployment of these interventions in Malaysian prisons.

Confronting the HIV, Tuberculosis, Addiction, and Incarceration Syndemic in Southeast Asia: Lessons Learned from Malaysia

PubMed Central

Culbert, Gabriel J.; Pillai, Veena; Bick, Joseph; Al-Darraji, Haider A.; Wickersham, Jeffrey A.; Wegman, Martin P.; Bazazi, Alexander R.; Ferro, Enrico; Copenhaver, Michael; Kamarulzaman, Adeeba; Altice, Frederick L.

2016-01-01

Throughout Southeast Asia, repressive drug laws have resulted in high rates of imprisonment in people who inject drugs and people living with HIV (PLH), greatly magnifying the harm associated with HIV, tuberculosis, and addiction. We review findings from Malaysia's largest prison to describe the synergistic effects of HIV, tuberculosis, addiction, and incarceration that contribute to a‘perfect storm’of events challenging public and personal health and offer insights into innovative strategies to control these converging epidemics. The majority of PLH who are imprisoned in Malaysia are opioid dependent. Although promoted by official policy, evidence-based drug treatment is largely unavailable, contributing to rapid relapse and/or overdose after release. Similarly, HIV treatment in prisons and compulsory drug treatment centers is sometimes inadequate or absent. The prevalence of active tuberculosis is high, particularly in PLH, and over 80% of prisoners and prison personnel are latently infected. Mandatory HIV testing and subsequent segregation of HIV-infected prisoners increases the likelihood of tuberculosis acquisition and progression to active disease, enlarging the reservoir of infection for other prisoners. We discuss strategies to control these intersecting epidemics including screening linked to standardized treatment protocols for all three conditions, and effective transitional programs for released prisoners. For example, recently introduced evidence-based interventions in prisons like antiretroviral therapy (ART) to treat HIV, isoniazid preventive therapy to treat latent tuberculosis infection, and methadone maintenance to treat opioid dependence, have markedly improved clinical care and reduced mortality. Since introduction of these interventions in September 2012, all-cause and HIV-related mortality have decreased by 50.0% and 75.7% respectively. We discuss the further deployment of these interventions in Malaysian prisons. PMID:27216260

Single-step affinity purification for fungal proteomics.

PubMed

Liu, Hui-Lin; Osmani, Aysha H; Ukil, Leena; Son, Sunghun; Markossian, Sarine; Shen, Kuo-Fang; Govindaraghavan, Meera; Varadaraj, Archana; Hashmi, Shahr B; De Souza, Colin P; Osmani, Stephen A

2010-05-01

A single-step protein affinity purification protocol using Aspergillus nidulans is described. Detailed protocols for cell breakage, affinity purification, and depending on the application, methods for protein release from affinity beads are provided. Examples defining the utility of the approaches, which should be widely applicable, are included.

Instructions to "push as hard as you can" improve average chest compression depth in dispatcher-assisted cardiopulmonary resuscitation.

PubMed

Mirza, Muzna; Brown, Todd B; Saini, Devashish; Pepper, Tracy L; Nandigam, Hari Krishna; Kaza, Niroop; Cofield, Stacey S

2008-10-01

Cardiopulmonary resuscitation (CPR) with adequate chest compression depth appears to improve first shock success in cardiac arrest. We evaluate the effect of simplification of chest compression instructions on compression depth in dispatcher-assisted CPR protocol. Data from two randomized, double-blinded, controlled trials with identical methodology were combined to obtain 332 records for this analysis. Subjects were randomized to either modified Medical Priority Dispatch System (MPDS) v11.2 protocol or a new simplified protocol. The main difference between the protocols was the instruction to "push as hard as you can" in the simplified protocol, compared to "push down firmly 2in. (5cm)" in MPDS. Data were recorded via a Laerdal ResusciAnne SkillReporter manikin. Primary outcome measures included: chest compression depth, proportion of compressions without error, with adequate depth and with total release. Instructions to "push as hard as you can", compared to "push down firmly 2in. (5cm)", resulted in improved chest compression depth (36.4 mm vs. 29.7 mm, p<0.0001), and improved median proportion of chest compressions done to the correct depth (32% vs. <1%, p<0.0001). No significant difference in median proportion of compressions with total release (100% for both) and average compression rate (99.7 min(-1) vs. 97.5 min(-1), p<0.56) was found. Modifying dispatcher-assisted CPR instructions by changing "push down firmly 2in. (5cm)" to "push as hard as you can" achieved improvement in chest compression depth at no cost to total release or average chest compression rate.

RESPONSE PROTOCOL TOOLBOX: OVERVIEW, STATUS UPDATE, AND RELATIONSHIP TO OTHER WATER SECURITY PRODUCTS

EPA Science Inventory

The Response Protocol Toolbox was released by USEPA to address the complex, multi-faceted challenges of a water utility's planning and response to the threat or act of intentional contamination of drinking water (1). The Toolbox contains guidance that may be adopted voluntarily,...

RESPONSE PROTOCOL TOOLBOX: OVERVIEW, STATUS UPDATE, AND RELATIONSHIP TO OTHER WATER SECURITY PRODUCTS

EPA Science Inventory

The Response Protocol Toolbox was released by USEPA to address the complex, multi-faceted challenges of a water utility's planning and response to the threat or act of intentional contamination of drinking water(1). The Toolbox contains guidance that may be adopted voluntarily, a...

RESPONSE PROTOCOL TOOLBOX OVERVIEW, STATUS UPDATE, AND RELATIONSHIP TO OTHER WATER SECURITY PRODUCTS

EPA Science Inventory

The Response Protocol Toolbox was released by USEPA to address the complex, multi-faceted challenges of a water utility's planning and response to the threat or act of intentional contamination of drinking water (1). The Toolbox contains guidance that may be adopted voluntarily,...

A Field Comparison of Sampling Protocols for Measuring Lead in Drinking Water

EPA Science Inventory

US EPA Region 5 conducted a sampling study that demonstrates existing sampling protocols used for the Lead and Copper Rule (LCR) underestimate peak and probable mass of lead released in a system with lead service lines (LSLs). This comparative stagnation sampling was conducted i...

Advancements Made to the Wingman Software-in-the-Loop (SIL) Simulation: How to Operate the SIL

DTIC Science & Technology

2017-12-01

public release; distribution is unlimited. NOTICES Disclaimers The findings in this report are not to be construed as an official Department of...4 5. How-To Guidelines to Set up the SIL 5 5.1 Equipment 5 5.1.1 Vehicle Mobility 5 5.1.2 ARES 6 5.1.3 Unity 6 5.1.4 WMI 7 5.1.5 Setup for...6.2 RTK 10 6.3 ARES 12 6.3 Unity3d 12 6.4 WMI 13 7. Conclusion and Next Steps 14 Approved for public release; distribution is unlimited. iv

Rise in Tornadoes, Floods Poses Risk to Colleges

ERIC Educational Resources Information Center

Larson, Scott

2008-01-01

In June the U.S Climate Change Science Program, which is sponsored by 13 government agencies, released a report saying that extreme weather like heat waves, heavy downpours, and superpowered hurricanes would be more common in the future. The timing of the report--coming just as officials in Iowa were surveying the damage from the swollen Iowa…

Network Science Experimentation Vision

DTIC Science & Technology

2015-09-01

Brian Rivera, Kevin Chan, Lisa Scott, Reginald Hobbs, Alice Leung, Will Dron , and Ritu Chadha Approved for public...release; distribution is unlimited. NOTICES Disclaimers The findings in this report are not to be construed as an official Department of the...Kott, Brian Rivera, Kevin Chan, Lisa Scott, and Reginald Hobbs Computational and Information Sciences Directorate, ARL Alice Leung and Will Dron

‘US Furr’ and ‘US Furr-ST’ Mandarin

USDA-ARS?s Scientific Manuscript database

This document marks the official release of ‘US Furr’, a hybrid of ‘Clementine’ x ‘Murcott’, and ‘US Furr-ST’, an irradiated variant of ‘US Furr’ with apparent field tolerance to citrus scab (causal agent Elsinoe fawcetti Bitanc. and Jenk.). The hybridization creating ‘US Furr’ and ultimately ‘US Fu...

75 FR 9411 - Official Release of the MOVES2010 Motor Vehicle Emissions Model for Emissions Inventories in SIPs...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-02

... hot-spot analyses at this time; the Agency will approve the model for such analyses in the near future...-Level Conformity Hot-Spot Analyses Availability of MOVES2010 and Support Materials Copies of the... for regional emissions analyses and CO hot-spot analyses for transportation conformity (73 FR 3464...

45 CFR 5.34 - Appeal of denials.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Release and Denial of Records § 5.34 Appeal of denials. (a) Right of appeal. You have the right to appeal... reasons why you believe that the FOIA exemption(s) we cited do not apply to the records that you requested... designated review official will consult with the General Counsel to ensure that the rights and interests of...

US Army Research Laboratory Visualization Framework Architecture Document

DTIC Science & Technology

2018-01-11

this report are not to be construed as an official Department of the Army position unless so designated by other authorized documents. Citation of...release; distribution is unlimited. 14. ABSTRACT Visualization of network science experimentation results is generally achieved using stovepipe...report documents the ARL Visualization Framework system design and specific details of its implementation. 15. SUBJECT TERMS visualization

Secondary Social Studies Teachers' Time Commitment When Addressing the Common Core State Standards

ERIC Educational Resources Information Center

Kenna, Joshua L.; Russell, William Benedict, III

2015-01-01

In 2010 the Common Core State Standards (CCSS) were officially released in America for mathematics and English language arts and soon adopted by 45 of the 50 states. However, within the English langue arts domain there were standards intended for secondary social studies teachers under the title, Common Core State Standards for English Language…

40 CFR 61.206 - Distribution and use of phosphogypsum for other purposes.

Code of Federal Regulations, 2010 CFR

2010-07-01

... be used. (7) A description of any measures which will be taken to prevent the uncontrolled release of... official in charge of the facility. (c) The Assistant Administrator for Air and Radiation may decide to... Air and Radiation decides to grant a request that EPA approve distribution and/or use of phosphogypsum...

40 CFR 61.206 - Distribution and use of phosphogypsum for other purposes.

Code of Federal Regulations, 2011 CFR

2011-07-01

... be used. (7) A description of any measures which will be taken to prevent the uncontrolled release of... official in charge of the facility. (c) The Assistant Administrator for Air and Radiation may decide to... Air and Radiation decides to grant a request that EPA approve distribution and/or use of phosphogypsum...

The Development of a Test System for the Evaluation of Reverse Osmosis Water Purification Membranes

DTIC Science & Technology

1984-06-01

processes consist of high rate filtration followed by the reverse osmosis system. Under the present concept there will be two units: one will produce 600...of the National Toxicology Program, National Institute of Health. No official data has. been released on the teratogenicity of D.MMP. Healh ýz

78 FR 14533 - Official Release of EMFAC2011 Motor Vehicle Emission Factor Model for Use in the State of California

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-06

... testing of interim versions of the model with air districts and Metropolitan Planning Organizations (MPOs... Motor Vehicle Emission Factor Model for Use in the State of California AGENCY: Environmental Protection... of the latest version of the California EMFAC model (short for EMission FACtor) for use in state...

14 CFR § 1214.607 - Media and public inquiries.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 5 2014-01-01 2014-01-01 false Media and public inquiries. § 1214.607... Mementos Aboard Space Shuttle Flights § 1214.607 Media and public inquiries. (a) Official Flight Kit. Information on the contents of OFK's will be routinely released to the media and to the public upon their...

Defense.gov Special Report: Defense Officials Release Operational Energy

Science.gov Websites

Strategy You have reached a collection of archived material. The content available is no longer being updated and may no longer be applicable as a result of changes in law, regulation and/or the Army, teams of quiet professionals are lightening the load of soldiers on the ground and

43 CFR 11.61 - Injury determination phase-general.

Code of Federal Regulations, 2013 CFR

2013-10-01

... resulted from the discharge of oil or release of a hazardous substance based upon the exposure pathway and...—injury definition; § 11.63—pathway determination; and § 11.64—testing and sampling methods, of this part... authorized official shall follow the guidance provided in the pathway section, § 11.63 of this part, to...

43 CFR 11.61 - Injury determination phase-general.

Code of Federal Regulations, 2014 CFR

2014-10-01

... resulted from the discharge of oil or release of a hazardous substance based upon the exposure pathway and...—injury definition; § 11.63—pathway determination; and § 11.64—testing and sampling methods, of this part... authorized official shall follow the guidance provided in the pathway section, § 11.63 of this part, to...

43 CFR 11.61 - Injury determination phase-general.

Code of Federal Regulations, 2011 CFR

2011-10-01

... resulted from the discharge of oil or release of a hazardous substance based upon the exposure pathway and...—injury definition; § 11.63—pathway determination; and § 11.64—testing and sampling methods, of this part... authorized official shall follow the guidance provided in the pathway section, § 11.63 of this part, to...

43 CFR 11.61 - Injury determination phase-general.

Code of Federal Regulations, 2012 CFR

2012-10-01

... resulted from the discharge of oil or release of a hazardous substance based upon the exposure pathway and...—injury definition; § 11.63—pathway determination; and § 11.64—testing and sampling methods, of this part... authorized official shall follow the guidance provided in the pathway section, § 11.63 of this part, to...

43 CFR 11.61 - Injury determination phase-general.

Code of Federal Regulations, 2010 CFR

2010-10-01

... resulted from the discharge of oil or release of a hazardous substance based upon the exposure pathway and...—injury definition; § 11.63—pathway determination; and § 11.64—testing and sampling methods, of this part... authorized official shall follow the guidance provided in the pathway section, § 11.63 of this part, to...

Foundations for Success: The Final Report of the National Mathematics Advisory Panel

ERIC Educational Resources Information Center

US Department of Education, 2008

2008-01-01

On March 13, 2008, the National Mathematics Advisory Panel submitted its Final Report to the President of the United States and the Secretary of Education, and it was officially released to the public on that date, as well. The Panel agrees that the delivery system in mathematics education--the system that translates mathematical knowledge into…

Enhancement of the Monet/Atonet Washington DC Network

DTIC Science & Technology

2003-01-01

Technologies Sponsored by Defense Advanced Research Projects Agency DARPA Order No. J792 APPROVED FOR PUBLIC RELEASE...representing the official policies, either expressed or implied, of the Defense Advanced Research Projects Agency or the U.S. Government...AIR FORCE RESEARCH LABORATORY INFORMATION DIRECTORATE ROME RESEARCH SITE ROME, NEW YORK This report has been reviewed by the Air Force

Renditions: Constraints Imposed by Laws on Torture

DTIC Science & Technology

2009-01-22

AVAILABILITY STATEMENT Approved for public release; distribution unlimited 13. SUPPLEMENTARY NOTES 14. ABSTRACT 15. SUBJECT TERMS 16. SECURITY ...suspended after the Italian government said testimony could reveal state secrets threatening Italy’s national security . “CIA-Linked Kidnapping Trial...raised against U.S. officials implicated national security and foreign policy considerations, and assessing the propriety of those considerations was

From Cloud to Mobile: Drawing down Big Info into Little Apps

ERIC Educational Resources Information Center

Herther, Nancy K.

2011-01-01

With the release of Google's App Inventor for Android, though still officially in beta, the company sought to make app development "simple but powerful" so that teachers could create study tips and quizzes, anyone could create geographic information systems (GIS) to help people find their way to some destination, and people could communicate over…

34 CFR 370.48 - What are the special requirements pertaining to the protection, use, and release of personal...

Code of Federal Regulations, 2011 CFR

2011-07-01

... periodic audit, preparing or producing any report, or conducting any evaluation of the performance of the... number, social security number, or any other official code or number by which an individual may be readily identified) related to, any individual requesting assistance under the CAP if— (1) An audit...

34 CFR 370.48 - What are the special requirements pertaining to the protection, use, and release of personal...

Code of Federal Regulations, 2010 CFR

2010-07-01

... periodic audit, preparing or producing any report, or conducting any evaluation of the performance of the... number, social security number, or any other official code or number by which an individual may be readily identified) related to, any individual requesting assistance under the CAP if— (1) An audit...

Improvements of Quantum Private Comparison Protocol Based on Cluster States

NASA Astrophysics Data System (ADS)

Zhou, Ming-Kuai

2018-01-01

Quantum private comparison aims to determine whether the secrets from two different users are equal or not by utilizing the laws of quantum mechanics. Recently, Sun and Long put forward a quantum private comparison (QPC) protocol by using four-particle cluster states (Int. J. Theor. Phys. 52, 212-218, 2013). In this paper, we investigate this protocol in depth, and suggest the corresponding improvements. Compared with the original protocol, the improved protocol has the following advantages: 1) it can release the requirements of authenticated classical channels and unitary operations; 2) it can prevent the malicious attack from the genuine semi-honest TP; 3) it can enhance the qubit efficiency.

Phase II Clinical Trial of Intraoral Grafting of Human Tissue Engineered Oral Mucosa

DTIC Science & Technology

2017-10-01

experimental arm subject in the small defect study. A protocol amendment in early 2017revised the study inclusionary criteria to include all non ...construed as an official Department of the Army position, policy or decision unless so designated by other documentation. REPORT DOCUMENTATION PAGE...group phase II study to assess the safety and efficacy for use of human EVPOME for soft tissue intraoral grafting procedures compared to the “gold

An Influence Analysis of Dissuading Nation States from Producing and Proliferating Weapons of Mass Destruction (WMD)

DTIC Science & Technology

2011-03-01

author and do not reflect the official policy or position of the Department of Defense or the U.S. Government. IRB Protocol number ______N/A__________...18 5. Lead Up to the Fission Device Test 1974 .........................................22 6. Maintaining Nuclear Policy 1974-1998...out to produce nuclear energy for research and civilian energy consumption. Its government maintained a policy of peace nuclear energy usage unless

Field Screening Method for 2,4-Dinitrotoluene in Soil

DTIC Science & Technology

1991-10-01

to be used for advertising or promotional purposes. Citation of brand names doesnot constitute an official endorsement or approval of the use of such... processed according to the tions of the protocols and results are shown in Table 8. method. After colordevelopment, four individuals were ANOVA...repeat process througho.: 30-minute pe- again for I minute. The solutions are filtered and the riod. absorbance read again at 570 nm. If 2,4-DNT is

Stemming the Flow of Improvised Explosive Device Making Materials through Global Export Control Regimes

DTIC Science & Technology

2012-09-01

reflect the official policy or position of the Department of Defense or the U.S. Government. IRB Protocol number ______N/A______. 12a. DISTRIBUTION...Warfare DHS Department of Homeland Security DoD Department of Defense DTMF Dual-Tone Multi-Frequency EOD Explosive Ordnance Disposal EU European...Organization JMTC Joint Multinational Training Command JTF Joint Task Force MANPADS Man Portable Air Defense Systems MERC Multilateral Export Control

Brazils Rise to Global Power

DTIC Science & Technology

2014-06-01

not reflect the official policy or position of the Department of Defense or the U.S. Government . IRB protocol number ____N/A____. 12a...economic power status, since the country is also a member of the Group of 8 (G-8), a forum for the governments of the world’s eight most powerful economies...English. This may pose methodological problems since the author will be relying largely on data published by the Brazilian government . Even with this

Positive Communications: The Keystone of Counterinsurgency Strategy

DTIC Science & Technology

2013-12-01

and do not reflect the official policy or position of the Department of Defense or the U.S. government. IRB protocol number ____N/A____. 12a...temporal data to isolate the casual effect of population engagements and radio broadcasts in relation to levels of insurgent violence over time and space...casual effect of population engagements and radio broadcasts in relation to levels of insurgent violence over time and space. The evidence supports our

Extended high dose letrozole regimen versus short low dose letrozole regimen as an adjuvant to gonadotropin releasing hormone antagonist protocol in poor responders undergoing IVF-ET.

PubMed

Fouda, Usama M; Sayed, Ahmed M

2011-12-01

To compare the efficacy and cost-effectiveness of extended high dose letrozole regimen/HPuFSH-gonadotropin releasing hormone antagonist (GnRHant) protocol with short low dose letrozole regimen/HPuFSH-GnRHant protocol in poor responders undergoing IVF-ET. In this randomized controlled trial, 136 women who responded poorly to GnRH agonist long protocol in their first IVF cycle were randomized into two equal groups using computer generated list and were treated in the second IVF cycle by either extended letrozole regimen (5 mg/day during the first 5 days of cycle and 2.5 mg/day during the subsequent 3 days) combined with HPuFSH-GnRHant protocol or short letrozole regimen (2.5 mg/day from cycle day 3-7) combined with HPuFSH-GnRHant protocol. There were no significant differences between both groups with regard to number of oocytes retrieved and clinical pregnancy rate (5.39 ± 2.08 vs. 5.20 ± 1.88 and 22.06% vs. 16.18%, respectively).The total gonadotropins dose and medications cost per cycle were significantly lower in extended letrozole group (44.87 ± 9.16 vs. 59.97 ± 14.91 ampoules and 616.52 ± 94.97 vs. 746.84 ± 149.21 US Dollars ($), respectively).The cost-effectiveness ratio was 2794 $ in extended letrozole group and 4616 $ in short letrozole group. Extended letrozole regimen/HPuFSH-GnRHant protocol was more cost-effective than short letrozole regimen/HPuFSH-GnRHant protocol in poor responders undergoing IVF-ET.

Short-term Outcomes following Concussion in the NFL: An 11-year Retrospective Study of Player Release Rate and Financial Loss

PubMed Central

Ramkumar, Prem; Navarro, Sergio Michael

2017-01-01

Objectives: The primary goal of this study was to assess the short-term outcomes among National Football League (NFL) players following concussion in terms of: (1) DNP protocol activation, (2) release rate at one and three years, and (3) mean salary reduction. A secondary goal of the study was to stratify the post-concussive release rate by franchise and player position. Methods: NFL player transaction records and publicly available weekly injury reports from August 2005 to January 2016 for NFL players were analyzed. All players immediately sustaining recorded concussions were evaluated for a change to inactive or do-not-play (DNP) status. The one-year and three-year release rate following concussion was defined as any player transitioning to inactivation, retirement, free agency, or any failure to return for a successive season on the same team’s active roster after one or three years from the initial concussion. Student’s t-test was used to compare release rates between non-concussed and concussed players at one and three years. Mean salary reduction per year following concussion was calculated using publicly available player contracts. Additionally, franchise-level and position-based analyses of the release rate were performed. Results: Of the total 5,451 NFL players retrospectively analyzed over the 11-year period, 373 sustained publicly reported concussions resulting in DNP protocol activation. The release rate of the post-concussive versus non-concussive player was 26% vs. 20% at 1 year (p<0.01) and 31% vs. 19% at 3 years (p<0.01). After analyzing individual player contracts, the mean year-over-year change in contract value for concussed players after DNP protocol activation was an overall salary reduction of $760,000/year ± $2,380,000. Figure 1 depicts the tendency of each NFL franchise to release an athlete following concussion within one and three years. Table 1 reports a position-based analysis in terms of concussion rate, mean salary reduction, and NFL career longevity. Conclusion: Our retrospective study demonstrates that NFL concussions resulting in DNP protocol activation leads to a statistically greater release rate among concussed NFL players than non-concussed players. Released players suffered reduction in year-over-year accumulated earnings, and particular franchises tended to release concussed players more than others. Position-based Concussion Statistics of Players by DNP Activation, Salary Reduction, Career LengthPosition GroupDNP ConcussionsMean Salary Reduction ($/yr)Average Career Length (yrs)DB75 (20.1%)280,0007.0WR66 (17.7%)1,760,0007.3OL49 (13.1%)1,190,0005.5TE46 (12.3%)333,0007.7RB40 (10.7%)140,0005.1LB39 (10.5%)720,0004.9DL31 (8.3%)540,0007.0QB27 (7.2%)2,440,0007.3Total373760,0006.4

Survival and Passage of Juvenile Chinook Salmon and Steelhead Passing through Bonneville Dam, 2011

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ploskey, Gene R.; Batten, G.; Cushing, Aaron W.

Pacific Northwest National Laboratory (PNNL) and subcontractors conducted an acoustic-telemetry study of juvenile salmonid fish passage and survival at Bonneville Dam in 2011. The study was conducted to assess the readiness of the monitoring system for official compliance studies under the 2008 Biological Opinion and Fish Accords and to assess performance measures including route-specific fish passage proportions, travel times, and survival based upon a virtual/paired-release model. The study relied on releases of live Juvenile Salmon Acoustic Telemetry System tagged smolts in the Columbia River and used acoustic telemetry to evaluate the approach, passage, and survival of passing juvenile salmon usingmore » a virtual release, paired reference release survival model. This study supports the U.S. Army Corps of Engineers’ continual effort to improve conditions for juvenile anadromous fish passing through Columbia River dams.« less

Real waiting times for surgery. Proposal for an improved system for their management.

PubMed

Abásolo, Ignacio; Barber, Patricia; González López-Valcárcel, Beatriz; Jiménez, Octavio

2014-01-01

In Spain, official information on waiting times for surgery is based on the interval between the indication for surgery and its performance. We aimed to estimate total waiting times for surgical procedures, including outpatient visits and diagnostic tests prior to surgery. In addition, we propose an alternative system to manage total waiting times that reduces variability and maximum waiting times without increasing the use of health care resources. This system is illustrated by three surgical procedures: cholecystectomy, carpal tunnel release and inguinal/femoral hernia repair. Using data from two Autonomous Communities, we adjusted, through simulation, a theoretical distribution of the total waiting time assuming independence of the waiting times of each stage of the clinical procedure. We show an alternative system in which the waiting time for the second consultation is established according to the time previously waited for the first consultation. Average total waiting times for cholecystectomy, carpal tunnel release and inguinal/femoral hernia repair were 331, 355 and 137 days, respectively (official data are 83, 68 and 73 days, respectively). Using different negative correlations between waiting times for subsequent consultations would reduce maximum waiting times by between 2% and 15% and substantially reduce heterogeneity among patients, without generating higher resource use. Total waiting times are between two and five times higher than those officially published. The relationship between the waiting times at each stage of the medical procedure may be used to decrease variability and maximum waiting times. Copyright © 2013 SESPAS. Published by Elsevier Espana. All rights reserved.

Instructions to “push as hard as you can” improve average chest compression depth in dispatcher-assisted Cardiopulmonary Resuscitation

PubMed Central

Mirza, Muzna; Brown, Todd B.; Saini, Devashish; Pepper, Tracy L; Nandigam, Hari Krishna; Kaza, Niroop; Cofield, Stacey S.

2008-01-01

Background and Objective Cardiopulmonary Resuscitation (CPR) with adequate chest compression depth appears to improve first shock success in cardiac arrest. We evaluate the effect of simplification of chest compression instructions on compression depth in dispatcher-assisted CPR protocol. Methods Data from two randomized, double-blinded, controlled trials with identical methodology were combined to obtain 332 records for this analysis. Subjects were randomized to either modified Medical Priority Dispatch System (MPDS) v11.2 protocol or a new simplified protocol. The main difference between the protocols was the instruction to “push as hard as you can” in the simplified protocol, compared to “push down firmly 2 inches (5cm)” in MPDS. Data were recorded via a Laerdal® ResusciAnne® SkillReporter™ manikin. Primary outcome measures included: chest compression depth, proportion of compressions without error, with adequate depth and with total release. Results Instructions to “push as hard as you can”, compared to “push down firmly 2 inches (5cm)”, resulted in improved chest compression depth (36.4 vs 29.7 mm, p<0.0001), and improved median proportion of chest compressions done to the correct depth (32% vs <1%, p<0.0001). No significant difference in median proportion of compressions with total release (100% for both) and average compression rate (99.7 vs 97.5 per min, p<0.56) was found. Conclusions Modifying dispatcher-assisted CPR instructions by changing “push down firmly 2 inches (5cm)” to “push as hard as you can” achieved improvement in chest compression depth at no cost to total release or average chest compression rate. PMID:18635306

Evaluation of the VIDAS Listeria (LIS) immunoassay for the detection of Listeria in foods using demi-Fraser and Fraser enrichment broths, as modification of AOAC Official Method 999.06 (AOAC Official Method 2004.06).

PubMed

Silbernagel, Karen M; Jechorek, Robert P; Kaufer, Amanda L; Johnson, Ronald L; Aleo, V; Brown, B; Buen, M; Buresh, J; Carson, M; Franklin, J; Ham, P; Humes, L; Husby, G; Hutchins, J; Jechorek, R; Jenkins, J; Kaufer, A; Kexel, N; Kora, L; Lam, L; Lau, D; Leighton, S; Loftis, M; Luc, S; Martin, J; Nacar, I; Nogle, J; Park, J; Schultz, A; Seymore, D; Smith, C; Smith, J; Thou, P; Ulmer, M; Voss, R; Weaver, V

2005-01-01

A multilaboratory study was conducted to compare the VIDAS LIS immunoassay with the standard cultural methods for the detection of Listeria in foods using an enrichment modification of AOAC Official Method 999.06. The modified enrichment protocol was implemented to harmonize the VIDAS LIS assay with the VIDAS LMO2 assay. Five food types--brie cheese, vanilla ice cream, frozen green beans, frozen raw tilapia fish, and cooked roast beef--at 3 inoculation levels, were analyzed by each method. A total of 15 laboratories representing government and industry participated. In this study, 1206 test portions were tested, of which 1170 were used in the statistical analysis. There were 433 positive by the VIDAS LIS assay and 396 positive by the standard culture methods. A Chi-square analysis of each of the 5 food types, at the 3 inoculation levels tested, was performed. The resulting average Chi square analysis, 0.42, indicated that, overall, there are no statistical differences between the VIDAS LIS assay and the standard methods at the 5% level of significance.

The interaction evolution model of mass incidents with delay in a social network

NASA Astrophysics Data System (ADS)

Huo, Liang'an; Ma, Chenyang

2017-10-01

Recent years have witnessed rapid development of information technology. Today, modern media is widely used for the purpose of spreading information rapidly and widely. In particular, through micro-blog promotions, individuals tend to express their viewpoints and spread information on the internet, which could easily lead to public opinions. Moreover, government authorities also disseminate official information to guide public opinion and eliminate any incorrect conjecture. In this paper, a dynamical model with two delays is investigated to exhibit the interaction evolution between the public and official opinion fields in network mass incidents. Based on the theory of differential equations, the interaction mechanism between two public opinion fields in a micro-blog environment is analyzed. Two delays are proposed in the model to depict the response delays of public and official opinion fields. Some stable conditions are obtained, which shows that Hopf bifurcation can occur as delays cross critical values. Further, some numerical simulations are carried out to verify theoretical results. Our model indicates that there exists a golden time for government intervention, which should be emphasized given the impact of modern media and inaccurate rumors. If the government releases official information during the golden time, mass incidents on the internet can be controlled effectively.

Gonadotrophin-releasing hormone antagonists for assisted conception.

PubMed

Al-Inany, H G; Abou-Setta, A M; Aboulghar, M

2006-07-19

Gonadotrophin-releasing hormone antagonists produce immediate suppression of gonadotrophin secretion, hence, they can be given after starting gonadotrophin administration. This has resulted in dramatic reduction in the duration of treatment cycle. Two different regimes have been described. The multiple-dose protocol involves the administration of 0.25 mg cetrorelix (or ganirelix) daily from day six to seven of stimulation, or when the leading follicle is 14 to15 mm, until human chorionic gonadotrophin (HCG) administration and the single-dose protocol involves the single administration of 3 mg cetrorelix on day seven to eight of stimulation. Assuming comparable clinical outcome, these benefits would justify a change from the standard long protocol of GnRH agonists to the new GnRH antagonist regimens. To evaluate the evidence regarding the efficacy of gonadotrophin-releasing hormone (GnRH) antagonists with the standard long protocol of GnRH agonists for controlled ovarian hyperstimulation in assisted conception. We searched Cochrane Menstrual Disorders and Subfertility Group's Specialised Register, MEDLINE and EMBASE databases from 1987 to February 2006, and handsearched bibliographies of relevant publications and reviews, and abstracts of scientific meetings. We also contacted manufacturers in the field. Randomized controlled studies comparing different protocols of GnRH antagonists with GnRH agonists in assisted conception cycles were included in this review. Two authors independently assessed trial quality and extracted data. If relevant data were missing or unclear, the authors have been consulted Twenty seven RCTs comparing the GnRH antagonist to the long protocol of GnRH agonist fulfilled the inclusion criteria. Clinical pregnancy rate was significantly lower in the antagonist group. (OR = 0.84, 95% CI = 0.72 - 0.97). The ongoing pregnancy/ live-birth rate showed the same significant lower pregnancy in the antagonist group (P = 0.03; OR 0.82, 95% CI 0.69 to 0.98).However, there was statistically significant reduction in incidence of severe OHSS with antagonist protocol. The relative risk ratio was (P = 0.01; RR 0.61, 95% CI 0.42 to 0.89). In addition, interventions to prevent OHSS (e.g. coasting, cycle cancellation) were administered more frequently in the agonist group (P = 0.03; OR 0.44, 95% CI 0.21 to 0.93). GnRH antagonist protocol is a short and simple protocol with good clinical outcome with significant reduction in incidence of severe ovarian hyperstimulation syndrome and amount of gonadotrophins but the lower pregnancy rate compared to the GnRH agonist long protocol necessitates counseling subfertile couples before recommending change from GnRH agonist to antagonist..

76 FR 6328 - Official Release of the January 2011 AP-42 Method for Estimating Re-Entrained Road Dust From...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-04

... Nonattainment and Maintenance Areas'' (EPA-420-B-10-040, December 2010). \\2\\ For estimating road dust from... maintenance areas and any PM 2.5 nonattainment and maintenance areas where re-entrained road dust is a... January 2011 AP-42 Method for Estimating Re-Entrained Road Dust From Paved Roads AGENCY: Environmental...

Trend of De La Salle Lipa Education Graduates' Performance in the Licensure Examination for Teachers

ERIC Educational Resources Information Center

Kalaw, Maria Theresa B.

2017-01-01

This study aimed to examine the trend of performance of De La Salle Lipa (DLSL) education graduates in the Licensure Examination for Teachers (LET). Quantitative trend analysis employed on the data collected from records officially released by the Professional Regulation Commission (PRC) for the years 2011 to 2015 revealed that the performance of…

Chinas Response to Terrorism

DTIC Science & Technology

2016-06-01

Information Office released a white paper on Xinjiang in October 2015 that describes Beijing’s policies aimed at enhancing ethnic unity and...effective research requires surveying a wide range of information sources. This report has sought to maximize a breadth of sources in order to...25 For a basic overview of Xinjiang, two official Chinese sources are PRC State Council Information Office, The History and

Enter the iPad (or Not?)

ERIC Educational Resources Information Center

Waters, John K.

2010-01-01

Few computing devices have sparked the burning gizmo lust ignited by the iPad. Apple's latest entry into the tablet PC market didn't generate much heat when it was first unveiled in January, but by April 3, the day of the official release, feverish customers were mobbing Apple stores. The company claims to have sold 300,000 iPads by midnight on…

Autophagy and TGF-Beta Antagonist Signaling in Breast Cancer at Premetastatic Sites

DTIC Science & Technology

2015-06-01

dormant legions. These inhibitors will be the drug leads for further medicinal chemistry and preclinical/clinical studies. 4 Body Overview Over the...autophagy, largely due to unexpected half-year delay of the official approval of our ACURO animal protocol . Below we report our progress, starting with...sections taken at various times after tail vein injection will enable us to verify that the anti-Coco MAb does not affect extravasation or homing but

Study of Managerial Challenges Confronting a New Agency: The Case of the Malaysian Maritime Enforcement Agency

DTIC Science & Technology

2015-06-01

of the author and do not reflect the official policy or position of the Department of Defense or the U.S. Government . IRB Protocol number ____N...maximum 200 words) The government of Malaysia decided to establish a new dedicated agency for law enforcement in the Malaysian Maritime Zone, in...CONFRONTING A NEW AGENCY: THE CASE OF THE MALAYSIAN MARITIME ENFORCEMENT AGENCY ABSTRACT The government of Malaysia decided to establish a

Shaping the National Guard in a Post-War Environment

DTIC Science & Technology

2012-09-01

IRR Individual Ready Reserve xiv JCS Joint Chiefs of Staff JFHQ Joint Forces Headquarters JTF Joint Task Force LAPD Los Angeles ... changing -of- the -guard/. 35 budget is a mirror of 2010, with future budgets projected to be capped at 2009 levels . In a troubled economy, DoD is...thesis are those of the author and do not reflect the official policy or position of the Department of Defense or the U.S. Government. IRB Protocol

Altered standards of care during an influenza pandemic: identifying ethical, legal, and practical principles to guide decision making.

PubMed

Levin, Donna; Cadigan, Rebecca Orfaly; Biddinger, Paul D; Condon, Suzanne; Koh, Howard K

2009-12-01

Although widespread support favors prospective planning for altered standards of care during mass casualty events, the literature includes few, if any, accounts of groups that have formally addressed the overarching policy considerations at the state level. We describe the planning process undertaken by public health officials in the Commonwealth of Massachusetts, along with community and academic partners, to explore the issues surrounding altered standards of care in the event of pandemic influenza. Throughout 2006, the Massachusetts Department of Public Health and the Harvard School of Public Health Center for Public Health Preparedness jointly convened a working group comprising ethicists, lawyers, clinicians, and local and state public health officials to consider issues such as allocation of antiviral medications, prioritization of critical care, and state seizure of private assets. Community stakeholders were also engaged in the process through facilitated discussion of case scenarios focused on these and other issues. The objective of this initiative was to establish a framework and some fundamental principles that would subsequently guide the process of establishing specific altered standards of care protocols. The group collectively identified 4 goals and 7 principles to guide the equitable allocation of limited resources and establishment of altered standards of care protocols. Reviewing and analyzing this process to date may serve as a resource for other states.

Longitudinal analysis of serological tests officially adopted by the Brazilian Ministry of Health for the diagnosis of canine visceral leishmaniasis in dogs vaccinated with Leishmune®.

PubMed

Marcondes, Mary; de Lima, Valéria Marçal Félix; de Araújo, Maria de Fátima Lereno; Hiramoto, Roberto Mitsuyoshi; Tolezano, José Eduardo; Vieira, Rafael F C; Biondo, Alexander W

2013-11-08

Development of vaccines against canine visceral leishmaniasis (CVL) may provide a prophylactic barrier, but antibody response detected by standard diagnostic techniques may not separate vaccinated from naturally infected dogs. Moreover, anti-Leishmania antibody levels in vaccinated dogs may be detectable for months. Accordingly, the aim of the present study was to comparatively evaluate an "in-house" ELISA with three serological tests officially adopted by the Brazilian Ministry of Health for the diagnosis of CVL in dogs vaccinated with Leishmune(®). A total of 18 mongrel dogs were submitted to a complete protocol of the vaccine, monitored and evaluated in 5 times (T0-T4) up to 180 days after T0. Twenty-one days after the first dose (T1), 50% of the dogs were seropositive by the "in-house" ELISA and 5.5% by IFAT, while by the official ELISA and DPP(®) CVL rapid test all dogs tested negative. At time T2, 42 days after of the first dose, 100%, 83.3%, 11.1%, and 5.5% of the dogs were seropositive by the "in-house" ELISA, IFAT, official ELISA kit and the DPP(®) CVL rapid test, respectively. Ninety days after the first dose (T3), 100%, 83.3%, 72.2% and 33.3% of the dogs were seropositive by the "in-house" ELISA, official ELISA kit, IFAT, and the DPP(®) CVL rapid test, respectively. Finally, at time T4, 88.8%, 33.3%, 11.1% and 5.5% of the dogs were seropositive by the "in-house" ELISA, official ELISA kit, DPP(®) CVL rapid test and IFAT, respectively. In conclusion, dogs vaccinated with Leishmune(®) cross-react by an "in-house" ELISA and by the three official Brazilian serological tests for the diagnosis of canine visceral leishmaniasis up to six months after the first vaccine dose, and may be mistakenly diagnosed and removed. Copyright © 2013 Elsevier B.V. All rights reserved.

Optimization of a Sample Processing Protocol for Recovery of ...

EPA Pesticide Factsheets

Journal Article Following a release of Bacillus anthracis spores into the environment, there is a potential for lasting environmental contamination in soils. There is a need for detection protocols for B. anthracis in environmental matrices. However, identification of B. anthracis within a soil is a difficult task. Processing soil samples helps to remove debris, chemical components, and biological impurities that can interfere with microbiological detection. This study aimed to optimize a previously used indirect processing protocol, which included a series of washing and centrifugation steps.

Human-Systems Integration (HSI) and the Network Integration Evaluations (NIEs), Part 2: A Deeper Dive into Mission Command Complexity and Cognitive Load

DTIC Science & Technology

2015-03-01

release; distribution is unlimited.    NOTICES    Disclaimers    The findings in this report are not to be construed as an official Department of the...endorsement or approval of the use thereof. Destroy this report when it is no longer needed. Do not return it to the originator.         ARL‐TR...Approved for public release; distribution is unlimited. ii REPORT  DOCUMENTATION PAGE  Form Approved OMB No. 0704‐0188 Public reporting burden for

Comparison of luteal estradiol patch and gonadotropin-releasing hormone antagonist suppression protocol before gonadotropin stimulation versus microdose gonadotropin-releasing hormone agonist protocol for patients with a history of poor in vitro fertilization outcomes.

PubMed

Weitzman, Vanessa N; Engmann, Lawrence; DiLuigi, Andrea; Maier, Donald; Nulsen, John; Benadiva, Claudio

2009-07-01

To compare IVF outcomes in poor-responder patients undergoing stimulation after luteal phase E(2) patch/GnRH antagonist (LPG) protocol versus microdose GnRH agonist protocol. Retrospective analysis. University-based IVF center. Forty-five women undergoing ovarian stimulation for IVF using the LPG protocol were compared with 76 women stimulated with the microdose GnRH agonist protocol from May 2005 to April 2006. Cancellation rate, number of oocytes retrieved, and clinical pregnancy rates. The mean number of oocytes (9.1 +/- 4.1 vs. 8.9 +/- 4.3) and mature oocytes (6.7 +/- 3.5 vs. 6.8 +/- 3.1) retrieved were similar, as were the fertilization rates (70.0% +/- 24.2% vs. 69.9% +/- 21.5%) and the number of embryos transferred (2.5 +/- 1.1 vs. 2.7 +/- 1.3). The cancellation rate was not significantly different between the groups (13/45, 28.9% vs. 23/76, 30.3%). Likewise, there were no significant differences among the implantation rate (15.0% vs. 12.5%), clinical pregnancy rate (43.3% vs. 45.1%), and ongoing pregnancy rate per transfer (33.3% vs. 26.0%) between both groups. This study demonstrates that the use of an E(2) patch and a GnRH antagonist during the preceding luteal phase in patients with a history of failed cycles can provide similar IVF outcomes when compared with the microdose GnRH agonist protocol.

Cortisol Release in Response to UVB Exposure in Xiphophorus Fish

PubMed Central

Contreras, Adam J.; Boswell, Mikki; Downs, Kevin P.; Pasquali, Amanda; Walter, Ronald B.

2014-01-01

Xiphophorus fishes are comprised of 26 known species. Interspecies hybridization between select species has been utilized to produce experimental models to study melanoma development. Xiphophorus melanoma induction protocols utilize ultraviolet light (UVB) to induce DNA damage and associated downstream tumorigenesis. However, the impact of induced stress caused by the UVB treatment of the experimental animals undergoing tumor induction protocols has not been assessed. Stress is an adaptive physiological response to excessive or unpredictable environmental stimuli. The stress response in fishes may be measured by assay of cortisol released into the water. Here, we present results from investigations of stress response during experimental treatment and UVB exposure in X. maculatus Jp 163 B, X. couchianus, and F1 interspecies hybrids produced from the mating X. maculatus Jp 163 B x X. couchianus. Overall, cortisol release rates for males and females after UVB exposure showed no statistical differences. At lower UVB doses (8 and 16 kJ/m2), X. couchianus exhibited 2 fold higher levels of DNA damage then either X. maculatus or the F1 hybrid. However, based on cortisol release rates, none of the fish types tested induced a primary stress response at the UVB lower doses (8 and 16 kJ/m2). In contrast, at a very high UVB dose (32 kJ/m2) both X. maculatus and the F1 hybrid showed a 5 fold increase in cortisol release rate. To determine the effect of pigmentation on UVB induced stress, wild type and albino X. hellerii were exposed to UVB (32 kJ/m2). Albino X. hellerii exhibited 3.7 fold increase in cortisol release while wild type X. hellerii did not exhibit a significant cortisol response to UVB. Overall, the data suggest the rather low UVB doses often employed in tumour induction protocols do not induce a primary stress response in Xiphophorus fishes. PMID:24625568

Does prolonged pituitary down-regulation with gonadotropin-releasing hormone agonist improve the live-birth rate in in vitro fertilization treatment?

PubMed

Ren, Jianzhi; Sha, Aiguo; Han, Dongmei; Li, Ping; Geng, Jie; Ma, Chaihui

2014-07-01

To evaluate the effects of a prolonged duration of gonadotropin-releasing hormone agonist (GnRH-a) in pituitary down-regulation for controlled ovarian hyperstimulation (COH) on the live-birth rate in nonendometriotic women undergoing in vitro fertilization and embryo transfer (IVF-ET). Retrospective cohort study. University-affiliated hospital. Normogonadotropic women undergoing IVF. Three hundred seventy-eight patients receiving a prolonged pituitary down-regulation with GnRH-a before ovarian stimulation and 422 patients receiving a GnRH-a long protocol. Live-birth rate per fresh ET. In comparison with the long protocol, the prolonged down-regulation protocol required a higher total dose of gonadotropins. A lower serum luteinizing hormone (LH) level on the starting day of gonadotropin and the day of human chorionic gonadotropin (hCG) and a fewer number of oocytes and embryos were observed in the prolonged down-regulation protocol. However, the duration of stimulation and number of high-quality embryos were comparable between the two groups. A statistically significantly higher implantation rate (50.27% vs. 39.69%), clinical pregnancy rate (64.02% vs. 56.87%) and live-birth rate per fresh transfer cycle (55.56% vs. 45.73%) were observed in the prolonged protocol. Prolonged down-regulation in a GnRH-a protocol might increase the live-birth rates in normogonadotropic women. Copyright © 2014 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

Microdose gonadotropin-releasing hormone agonist flare-up protocol versus multiple dose gonadotropin-releasing hormone antagonist protocol in poor responders undergoing intracytoplasmic sperm injection-embryo transfer cycle.

PubMed

Kahraman, Korhan; Berker, Bulent; Atabekoglu, Cem Somer; Sonmezer, Murat; Cetinkaya, Esra; Aytac, Rusen; Satiroglu, Hakan

2009-06-01

To compare the efficacy of microdose GnRH agonist (GnRH-a) flare-up and multiple dose GnRH antagonist protocols in patients who have a poor response to a long luteal GnRH-a protocol. Prospective, randomized, clinical study. University hospital. Forty-two poor responder patients undergoing intracytoplasmic sperm injection (ICSI)-embryo transfer cycle. Twenty-one patients received microdose leuprolide acetate (LA) (50 microg twice daily) starting on the second day of withdrawal bleeding. The other 21 patients received 0.25 mg of cetrorelix daily when the leading follicle reached 14 mm in diameter. Serum E(2) levels, number of growing follicles and mature oocytes, embryo quality, dose of gonadotropin used, cancellation, fertilization, implantation rate and pregnancy rate (PR). The mean serum E(2) concentration on the day of hCG administration was significantly higher in the microdose GnRH-a group than in the GnRH antagonist group (1,904 vs. 1,362 pg/mL). The clinical PRs per started cycle of microdose GnRH-a and GnRH antagonist groups were 14.2% and 9.5%, respectively. There were no statistically significant differences in the other ovulation induction characteristics, fertilization and implantation rates. Microdose GnRH-a flare-up protocol and multiple dose GnRH antagonist protocol seem to have similar efficacy in improving treatment outcomes of poor responder patients.

Stimulation of the young poor responder: comparison of the luteal estradiol/gonadotropin-releasing hormone antagonist priming protocol versus oral contraceptive microdose leuprolide.

PubMed

Shastri, Shefali M; Barbieri, Elizabeth; Kligman, Isaac; Schoyer, Katherine D; Davis, Owen K; Rosenwaks, Zev

2011-02-01

To evaluate in vitro fertilization (IVF) cycle outcomes in young poor responders treated with a luteal estradiol/gonadotropin-releasing hormone antagonist (E(2)/ANT) protocol versus an oral contraceptive pill microdose leuprolide protocol (OCP-MDL). Retrospective cohort. Academic practice. Poor responders: 186 women, aged <35 years undergoing IVF with either E(2)/ANT or OCP-MDL protocols. None. Clinical pregnancies, oocytes retrieved, cancellation rate. Patients in the E(2)/ANT group had a greater gonadotropin requirement (71.9 ± 22.2 vs. 57.6 ± 25.7) and lower E(2) level (1,178.6 ± 668 vs. 1,627 ± 889), yet achieved similar numbers of oocytes retrieved and fertilized, and a greater number of embryos transferred (2.3 ± 0.9 vs. 2.0 ± 1.1) with a better mean grade (2.14 ± .06 vs. 2.7 ± 1.8) compared with the OCP/MDL group. The E2/ANT group exhibited a trend toward improved implantation rates (30.5% vs. 21.1%) and ongoing pregnancy rates per started cycle: 44 out of 117 (37%) versus 17 out of 69 (25%). Poor responders aged <35 years may be treated with the aggressive E(2)/ANT protocol to improve cycle outcomes. Both protocols remain viable options for this group. Adequately powered, randomized clinical comparison appears justified. Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

Decontamination and management of human remains following incidents of hazardous chemical release.

PubMed

Hauschild, Veronique D; Watson, Annetta; Bock, Robert

2012-01-01

To provide specific guidance and resources for systematic and orderly decontamination of human remains resulting from a chemical terrorist attack or accidental chemical release. A detailed review and health-based decision criteria protocol is summarized. Protocol basis and logic are derived from analyses of compound-specific toxicological data and chemical/physical characteristics. Guidance is suitable for civilian or military settings where human remains potentially contaminated with hazardous chemicals may be present, such as sites of transportation accidents, terrorist operations, or medical examiner processing points. Guidance is developed from data-characterizing controlled experiments with laboratory animals, fabrics, and materiel. Logic and specific procedures for decontamination and management of remains, protection of mortuary affairs personnel, and decision criteria to determine when remains are sufficiently decontaminated are presented. Established procedures as well as existing materiel and available equipment for decontamination and verification provide reasonable means to mitigate chemical hazards from chemically exposed remains. Unique scenarios such as those involving supralethal concentrations of certain liquid chemical warfare agents may prove difficult to decontaminate but can be resolved in a timely manner by application of the characterized systematic approaches. Decision criteria and protocols to "clear" decontaminated remains for transport and processing are also provided. Once appropriate decontamination and verification have been accomplished, normal procedures for management of remains and release can be followed.

A Broader Look at the U.S. Employment Situation and the Importance of a Good Education

ERIC Educational Resources Information Center

Greenstone, Michael; Looney, Adam

2011-01-01

The January employment numbers, released today by the U.S. Department of Labor, present mixed evidence about the state of the labor market. While the unemployment rate dropped to 9 percent, payrolls were just better than flat, increasing by only 36,000 jobs last month. Much attention is given to the official unemployment rate, which is certainly…

Myeloid-Derived Suppressor Cells in Checkpoint Protein Inhibition for Melanoma

DTIC Science & Technology

2017-09-01

Army Medical Research and Materiel Command Fort Detrick, Maryland 21702-5012 DISTRIBUTION STATEMENT: Approved for Public Release...official Department of the Army position, policy or decision unless so designated by other documentation. REPORT DOCUMENTATION PAGE Form Approved...6402 9. SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) U.S. Army Medical Research and Materiel Command Fort

Japan-U.S. Relations: Issues for Congress

DTIC Science & Technology

2008-12-30

aggression in the World War II period. Despite underlying distrust, Tokyo’s relationships with Beijing and, until recently, Seoul appear to be on a solid...the release of government documents. # In concert with the leadership in Beijing , which has been keen to shore up its foreign relations...Sichuan province, the first foreign team that Beijing accepted. The official reconciliation, however, may be challenged by sentiment among the

Prostate Cancer Biospecimen Cohort Study

DTIC Science & Technology

2017-10-01

opinions and/or findings contained in this report are those of the author(s) and should not be construed as an official Department of the Army...SPONSOR/MONITOR’S REPORT NUMBER(S) 12. DISTRIBUTION / AVAILABILITY STATEMENT Approved for Public Release; Distribution Unlimited 13. SUPPLEMENTARY NOTES...14. ABSTRACT The goal of the study is development of a Prostate Cancer Biorepository Network (PCBN) resource site with high quality and well

Universal Open Power, Communications, and Control for Assistive Devices

DTIC Science & Technology

2017-10-01

The views, opinions and/or findings contained in this report are those of the author(s) and should not be construed as an official Department of the...SPONSOR/MONITOR’S REPORT NUMBER(S) 12. DISTRIBUTION / AVAILABILITY STATEMENT Approved for Public Release; Distribution Unlimited 13. SUPPLEMENTARY NOTES...flexible energy configuration, advanced high bandwidth sensing, and high energy density actuation technology. This project will advance the state-of

Radio Signal Augmentation for Improved Training of a Convolutional Neural Network

DTIC Science & Technology

2016-09-01

official government endorsement or approval of commercial products or services referenced in this report. Bluetooth ® is a registered...trademark of Bluetooth SIG, Inc.. Nuand™ and blade RF™ are trademarks of Nurand, LLC. Released by E. R. Buckland, Head IO Support to National... Bluetooth ® computer mouse, and Bluetooth ® search from a mobile cellular phone. Qualitatively, model Moffset dramatically outperformed model Mclean in

Aircraft Survivability: Aircraft Battle Damage and Repair, Summer 2007

DTIC Science & Technology

2007-01-01

Modeling and Analysis Program ( TMAP ) Missile Modeling System for Advanced Investigation of Countermeasures (MOSAIC) & Joint Surface-to-Air Missle... TMAP Threat System Models (TSM) into engagement simulations (MOSAIC [IR] and JSAMS [RF]). This 3-year project will integrate and fully test six...three per engagement simulation) JASC priority TMAP TSMs in official releases of MOSAIC and JSAMS. Project Engineers— Luke Borntrager (USAF, AFRL) and

The Maryland Large-Scale Integrated Neurocognitive Architecture

DTIC Science & Technology

2008-03-01

Visual input enters the network through the lateral geniculate nucleus (LGN) and is passed forward through visual brain regions (V1, V2, and V4...University of Maryland Sponsored by Defense Advanced Research Projects Agency DARPA Order No. V029 APPROVED FOR PUBLIC RELEASE...interpreted as necessarily representing the official policies, either expressed or implied, of the Defense Advanced Research Projects Agency or the U.S

Personnel-General: A Guide to Protocol and Etiquette for Official Entertainment

DTIC Science & Technology

2001-12-11

they are not announced and will have to seek out their host and apologize for their tardiness . At a large function it may not be possible for...X PANAMA X 31DA PAM 600–60 • 11 December 2001 Table 7–1 Record of dietary restrictions—Continued PARAGUAY X PERU X PHILIPPINES X POLAND X PORTUGAL X...President of the Republic of Peru PHILIPPINES His Excellency, the President of the Republic of the Philippines POLAND His Excellency, the President of

Increased Vulnerability to Soman Exposure in Aged Compared to Adult F344 Rats

DTIC Science & Technology

2016-10-01

or the U.S. Government. The experimental protocol was approved by the Animal Care and Use Committee at the United States Army Medical Research...Laboratory Animals and the Animal Welfare Act of 1966 (P.L. 89-544), as amended. The use of trade names does not constitute an official endorsement or...medical countermeasures to CWNAs has been conducted on young adult male animal models of CWNA exposure, focusing on the potential for drug therapies to

Surface Sampling-Based Decontamination Studies and Protocol for Determining Sporicidal Efficacy of Gaseous Fumigants on Military-Relevant Surfaces

DTIC Science & Technology

2008-09-01

related scenarios related to US armed forces around the world . In the civilian setting, complete decontamination is the only accepted criteria before a...observation, a door for sample introduction, and four ports on the front panel for sensor placement. All glass surfaces were covered when used with CD gas...1999, 281, 1735-1745. 9. AOAC International Method 966.04; Official Methods of Analisis , 21’t ed.; Chapter 6: AOAC International: Gaithersburg, MD

A System Dynamics Approach to the Efficacy of Oxime Therapy in Sub Lethal Exposure to Sarin Gas

DTIC Science & Technology

2015-06-18

effective treatments , including antidotes, is considered to contribute to this high mortality rate (Buckley et al., 2004:1231). The efficacy of current...officials to reduce the risk associated with high -consequence threats”. Nerve agents, such as Sarin gas, are considered high consequence threats...The threat of use of agents such as Sarin is as much a threat today as any other time in our history. However, the suggested treatment protocol is

Analysis and calibration of Safecasta data relative to the 2011 Fukushima Daiichi nuclear accident

NASA Astrophysics Data System (ADS)

Cervone, G.; Hultquist, C.

2017-12-01

Citizen-led movements producing scientific hazard data during disasters are increasingly common. After the Japanese earthquake-triggered tsunami in 2011, and the resulting radioactive releases at the damaged Fukushima Daiichi nuclear power plants, citizens monitored on-ground levels of radiation with innovative mobile devices built from off-the-shelf components. To date, the citizen-led Safecast project has recorded 50 million radiation measurements world- wide, with the majority of these measurements from Japan. A robust methodology is presented to calibrate contributed Safecast radiation measurements acquired between 2011 and 2016 in the Fukushima prefecture of Japan. The Safecast data are calibrated using official observations acquired by the U.S. Department of Energy at the time of the 2011 Fukushima Daiichi power plant nuclear accident. The methodology performs a series of interpolations between the official and contributed datasets at specific time windows and at corresponding spatial locations. The coefficients found are aggregated and interpolated using cubic and linear methods to generate time dependent calibration function. Normal background radiation, decay rates and missing values are taken into account during the analysis. Results show that the official Safecast static transformation function overestimates the official measurements because it fails to capture the presence of two different Cesium isotopes and their changing ratio with time. The new time dependent calibration function takes into account the presence of different Cesium isotopes, and minimizes the error between official and contributed data. This time dependent Safecast calibration function is necessary until 2030, after which date the error caused by the isotopes ratio will become negligible.

Efficacy and Safety of Immediate-Release Methylphenidate Treatment for Preschoolers with ADHD

ERIC Educational Resources Information Center

Greenhill, Laurence; Kollins, Scott; Abikoff, Howard; McCracken, James; Riddle, Mark; Swanson, James; McGough, James; Wigal, Sharon; Wigal, Tim; Vitiello, Benedetto; Skrobala, Anne; Posner, Kelly; Ghuman, Jaswinder; Cunningham, Charles; Davies, Mark; Chuang, Shirley; Cooper, Tom

2006-01-01

Objective: The Preschool ADHD Treatment Study (PATS) was a NIMH-funded, six-center, randomized, controlled trial to determine the efficacy and safety of immediate-release methylphenidate (MPH-IR), given t.i.d. to children ages 3 to 5.5 years with attention-deficit/hyperactivity disorder (ADHD). Method: The 8-phase, 70-week PATS protocol included…

High Power Quantum Cascade Laser for Terahertz Imaging

DTIC Science & Technology

2012-03-01

NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA THESIS Approved for public release, distribution is unlimited HIGH POWER QUANTUM...Second Reader: Fabio Alves THIS PAGE INTENTIONALLY LEFT BLANK i REPORT DOCUMENTATION PAGE Form Approved OMB No. 0704-0188 Public reporting...Department of Defense or the U.S. Government. IRB Protocol Number: N/A 12a. DISTRIBUTION / AVAILABILITY STATEMENT Approved for public release

Techniques for rearing and releasing nonmigratory cranes: Lessons from the Mississippi Sandhill Crane program

USGS Publications Warehouse

Ellis, D.H.; Olsen, Glenn H.; Gee, G.F.; Nicolich, Jane M.; O'Malley, K.E.; Nagendran, Meenakshi; Hereford, Scott G.; Range, P.; Harper, W.T.; Ingram, R.P.; Smith, D.G.

1992-01-01

Captive-reared Mississippi sandhill cranes (Grus canadensis pulla) reared at the Patuxent Wildlife Research Center (Patuxent) have been released at the Mississippi Sandhill Crane National Wildlife Refuge (MSCNWR) since 1981. Of 131 birds released through December 1990, 103 were reared by foster parents. The remaining 28 were experimentally hand-reared in 1989 and 1990. After refining release procedures, parent-reared birds have integrated into the wild flock, many have survived, and some have bred. Releases of hand-reared cranes elsewhere in the 1970's were largely unsuccessful, at least in part due to the lack of a lengthy acclimation period. A new hand-rearing protocol holds promise in producing release-worthy birds. The technique employs some features first used in the 1960's (e.g., a costume for the human caretaker and model crane heads used to train chicks to feed). In the mid-1980's, the following features were added: (1) the costumed caretaker was given a visor and feathers, (2) a taxidermic crane head or a hand puppet was held or suspended from the ceiling for use in stimulating chicks to feed, (3) a taxidermic mount of a brooding crane supplied warmth, (4) a full-sized live crane was maintained in an adjacent pen and in visual contact with neonatal young to provide an imprinting model, and (5) a small group of adult (or subadult) cranes was penned adjacent to the outdoor chick pens to provide socialization models. Recent releases of Mississippi sandhill cranes hand-reared according to this protocol and released in Mississippi have had high first-year survival rates. The now-operational technique holds promise for producing large numbers of release-worthy birds.

Releasing captive-reared masked bobwhite for population recovery: A review

USGS Publications Warehouse

Gall, S.A.; Kuvlesky, W.P.; Gee, G.; Brennan, L.A.; Palmer, W.E.; Burger, L.W.; Pruden, T.L.

2000-01-01

Efforts to re-establish the endangered masked bobwhite (Colinus virginianus ridgwayi) to it's former southern Arizona range have been ongoing since establishment of the Buenos Aires National Wildlife Refuge in 1986. Pre-release conditioning techniques developed prior to Refuge establishment continued to be utilized in an effort to improve post-release survival of captive-reared masked bobwhite chicks. Foremost among these techniques was the use of wild Texas bobwhite (C. v. texanus) males as foster parents which were paired with all broods released on the Refuge. The efficacy of this technique was evaluated using radio telemetry in 1994, and the results indicated that the use of foster Texas males was not as effective as had been presumed because post-release chick survival was poor. Therefore, in 1995 pre-release conditioning protocol were modified in an effort to improve post-release survival. The primary intent of these modifications was to emphasize wild behavior among chicks prior to release. Modifications to established protocol included imprinting chicks to adult bobwhites immediately after eggs hatched and exposing 1-to-2 day old chicks to natural foods (insects and seeds) while they were in brooder units. Foster parents and their respective broods were then placed in flight pens that mimicked the natural conditions that would confront broods upon release. Family groups were held in flight pens for several weeks for acclimatization purposes and then transported to temporary enclosures erected at release sites where they were held for a week and then released. Finally all releases were conducted during fall after covey formation was apparent to ensure that foster parents and released chicks remained with a group of birds. Preliminary results indicated that post-release chick survival was higher than what was observed in 1994. Pre-conditioning research will continue in an effort to further quantify post-release survival of masked bobwhite chicks. Although the results of this research project are preliminary, it is possible that pre-release conditioning techniques developed for masked bobwhites will prove useful to quail reestablishment efforts throughout North America.

A Hybrid Analysis for Security Protocols with State

DTIC Science & Technology

2014-07-16

Approved for Public Release; Distribution Unlimited. 14-1013. A Hybrid Analysis for Security Protocols with State∗ John D. Ramsdell Daniel J ...their consequences in the anno - tated protocol theory Tannot(Π, ) use only the limited vocabulary of Tbnd(Π); we call them bridge lemmas. Lemma 3 is a...and we proved it using pvs. Lemma 1 (Prefix Boot Extend). ∀π ∈ path, t :>, i, k ∈ N. i ≤ k ∧ π(k) has t ⊃ subterm(π(i), π(k)) ∨ ∃ j ∈ N. i ≤ j < k ∧ π

PCoD Lite - Using an Interim PCoD Protocol to Assess the Effects of Disturbance Associated with US Navy Exercises on Marine Mammal Populations

DTIC Science & Technology

2015-09-30

1 DISTRIBUTION STATEMENT A. Approved for public release; distribution is unlimited. PCoD Lite - Using an Interim PCoD Protocol to Assess...US National Research Council (NRC 2005). Here, we provide an insight into how the Interim PCoD approach (Harwood et al. 2014, King et al. 2015...illustrate how the interim PCoD protocol can be used to inform the process of determining whether or not Navy activities are likely to have an impact on

PCoD Lite - Using an Interim PCoD Protocol to Assess the Effects of Disturbance Associated with US Navy Exercises on Marine Mammal Populations

DTIC Science & Technology

2014-09-30

1 DISTRIBUTION STATEMENT A. Approved for public release; distribution is unlimited. PCoD Lite - Using an Interim PCoD Protocol to Assess...Skookum Tom Road Friday Harbor, WA, USA phone: 1-360-370-5493 email: jw@smrullc.com Award Number: N000141410406 http://www.smrumarine.com/ pcod ...DATE 30 SEP 2014 2. REPORT TYPE 3. DATES COVERED 00-00-2014 to 00-00-2014 4. TITLE AND SUBTITLE PCoD Lite - Using an Interim PCoD Protocol to

Validation protocol of analytical procedures for quantification of drugs in polymeric systems for parenteral administration: dexamethasone phosphate disodium microparticles.

PubMed

Martín-Sabroso, Cristina; Tavares-Fernandes, Daniel Filipe; Espada-García, Juan Ignacio; Torres-Suárez, Ana Isabel

2013-12-15

In this work a protocol to validate analytical procedures for the quantification of drug substances formulated in polymeric systems that comprise both drug entrapped into the polymeric matrix (assay:content test) and drug released from the systems (assay:dissolution test) is developed. This protocol is applied to the validation two isocratic HPLC analytical procedures for the analysis of dexamethasone phosphate disodium microparticles for parenteral administration. Preparation of authentic samples and artificially "spiked" and "unspiked" samples is described. Specificity (ability to quantify dexamethasone phosphate disodium in presence of constituents of the dissolution medium and other microparticle constituents), linearity, accuracy and precision are evaluated, in the range from 10 to 50 μg mL(-1) in the assay:content test procedure and from 0.25 to 10 μg mL(-1) in the assay:dissolution test procedure. The robustness of the analytical method to extract drug from microparticles is also assessed. The validation protocol developed allows us to conclude that both analytical methods are suitable for their intended purpose, but the lack of proportionality of the assay:dissolution analytical method should be taken into account. The validation protocol designed in this work could be applied to the validation of any analytical procedure for the quantification of drugs formulated in controlled release polymeric microparticles. Copyright © 2013 Elsevier B.V. All rights reserved.

Direct data access protocols benchmarking on DPM

NASA Astrophysics Data System (ADS)

Furano, Fabrizio; Devresse, Adrien; Keeble, Oliver; Mancinelli, Valentina

2015-12-01

The Disk Pool Manager is an example of a multi-protocol, multi-VO system for data access on the Grid that went though a considerable technical evolution in the last years. Among other features, its architecture offers the opportunity of testing its different data access frontends under exactly the same conditions, including hardware and backend software. This characteristic inspired the idea of collecting monitoring information from various testbeds in order to benchmark the behaviour of the HTTP and Xrootd protocols for the use case of data analysis, batch or interactive. A source of information is the set of continuous tests that are run towards the worldwide endpoints belonging to the DPM Collaboration, which accumulated relevant statistics in its first year of activity. On top of that, the DPM releases are based on multiple levels of automated testing that include performance benchmarks of various kinds, executed regularly every day. At the same time, the recent releases of DPM can report monitoring information about any data access protocol to the same monitoring infrastructure that is used to monitor the Xrootd deployments. Our goal is to evaluate under which circumstances the HTTP-based protocols can be good enough for batch or interactive data access. In this contribution we show and discuss the results that our test systems have collected under the circumstances that include ROOT analyses using TTreeCache and stress tests on the metadata performance.

The poison center role in biological and chemical terrorism.

PubMed

Krenzelok, E P; Allswede, M P; Mrvos, R

2000-10-01

Nuclear, biological and chemical (NBC) terrorism countermeasures are a major priority with municipalities, healthcare providers, and the federal government. Significant resources are being invested to enhance civilian domestic preparedness by conducting education at every response level in anticipation of a NBC terroristic incident. The key to a successful response, in addition to education, is integration of efforts as well as thorough communication and understanding the role that each agency would play in an actual or impending NBC incident. In anticipation of a NBC event, a regional counter-terrorism task force was established to identify resources, establish responsibilities and coordinate the response to NBC terrorism. Members of the task force included first responders, hazmat, law enforcement (local, regional, national), government officials, the health department, and the regional poison information center. Response protocols were developed and education was conducted, culminating in all members of the response task force becoming certified NBC instructors. The poison center participated actively in 3 incidents of suspected biologic and chemical terrorism: an alleged anthrax-contaminated letter sent to a women's health clinic; a possible sarin gas release in a high school: and a potential anthrax/ebola contamination incident at an international airport. All incidents were determined hoaxes. The regional response plan establishes the poison information center as a common repository for all cases in a biological or chemical incident. The poison center is one of several critical components of a regional counterterrorism response force. It can conduct active and passive toxicosurveillance and identify sentinel events. To be responsive, the poison center staff must be knowledgeable about biological and chemical agents. The development of basic protocols and a standardized staff education program is essential. The use of the RaPiD-T (R-recognition, P-protection, D-detection, T-triage/treatment) course can provide basic staff education for responding to this important but rare consultation to the poison center.

A systematic study of the release of bisphenol A by orthodontic materials and its biological effects.

PubMed

Halimi, Abdelali; Benyahia, Hicham; Bahije, Loubna; Adli, Hanane; Azeroual, Mohamed-Faouzi; Zaoui, Fatima

2016-12-01

Bisphenol A (BPA) is a synthetic chemical substance used as a starting ingredient in the manufacturing process of a number or orthodontic materials. It is a well-known endocrine disruptor with low estrogenic properties. The aim of this investigation is to present a systematic review regarding the issue of bisphenol A release by orthodontic materials and its impact in orthodontics. A systematic analysis was performed by electronic search (between 1936 and 2015) on several data bases. The search was limited by using several specific key-words in two languages, English and French. Two investigators selected the responses, which met the selection criteria. Of the 376 studies found, only 21 met our selection criteria: 11 of these dealt with the release of bisphenol by orthodontic materials and 10 in vitro studies described the effects of BPA leaching from orthodontic materials on human and murine cells. The rate of BPA release was well below the daily tolerable intake (DTI) (50mg/kg/day in 2006, then 50μg/kg/day in 2015) according to the European Food Safety Authority (EFSA). Theoretical exposure to BPA was 11,000 times lower than recommendations. However, other studies have shown the presence of BPA and of monomers released in large quantities at very low doses. The effects of observed BPA varied significantly (toxic and carcinogenic potential) while some studies found no effects at all. The relatively small number of studies dealing with the release of Bisphenol A by orthodontic materials, apart from orthodontic materials and their significant biological effects, has led to the absence of standard protocols and has hindered precise determination of released BPA. Moreover, the lack of coherence between the various methodological approaches and variations in the experimental protocols have resulted in a low level of proof regarding the impact of BPA by orthodontic materials. Through this study, the authors encourage clinicians to observe the following recommendations designed to reduce the amount of BPA released by materials used in orthodontics: keep the tip of the light-curing lamp as close as possible to the composite and perform indirect rather than direct light-curing; Pumice-polish the composite after bonding so as to reduce the potential amount of BPA released; reduce exposure by brushing or rinsing with a mouthwash during the first hour after bonding; follow a standardized, reproducible and expert-validated research protocol aimed at better understanding of BPA release. Copyright © 2016 CEO. Published by Elsevier Masson SAS. All rights reserved.

Building sandbars in Grand Canyon

USGS Publications Warehouse

2016-01-01

Now, by implementing a new strategy that calls for repeated releases of large volumes of water from the dam, the U.S. Department of the Interior seeks to increase the size and number of these sandbars. Three years into the “High Flow Experiment” protocol, the releases appear to be achieving the desired effect. Many sandbars have increased in size following each controlled flood and the cumulative results of the first three releases suggests that sandbar declines may be reversed if controlled floods can be implemented frequently enough.

Building sandbars in the Grand Canyon

USGS Publications Warehouse

Grams, Paul E.; Schmidt, John C.; Wright, Scott A.; Topping, David; Melis, Theodore S.; Rubin, David M.

2015-01-01

Now, by implementing a new strategy that calls for repeated releases of large volumes of water from the dam, the U.S. Department of the Interior (DOI) seeks to increase the size and number of these sandbars. Three years into the "high-flow experiment" (HFE) protocol, the releases appear to be achieving the desired effect. Many sandbars have increased in size following each controlled flood, and the cumulative results of the first three releases suggest that sandbar declines may be reversed if controlled floods can be implemented frequently enough.

Development of a neuromuscular electrical stimulation protocol for sprint training.

PubMed

Russ, David W; Clark, Brian C; Krause, Jodi; Hagerman, Fredrick C

2012-09-01

Sprint training is associated with several beneficial adaptations in skeletal muscle, including an enhancement of sarcoplasmic reticulum (SR) Ca(2+) release. Unfortunately, several patient populations (e.g., the elderly, those with cardiac dysfunction) that might derive great benefit from sprint exercise are unlikely to tolerate it. The purpose of this report was to describe the development of a tolerable neuromuscular electrical stimulation (NMES) protocol that induces skeletal muscle adaptations similar to those observed with sprint training. Our NMES protocol was modeled after a published sprint exercise protocol and used a novel electrode configuration and stimulation sequence to provide adequate training stimulus while maintaining subject tolerance. Nine young, healthy subjects (four men) began and completed the training protocol of the knee extensor muscles. All subjects completed the protocol, with ratings of discomfort far less than those reported in studies of traditional NMES. Training induced significant increases in SR Ca(2+) release and citrate synthase activity (~16% and 32%, respectively), but SR Ca(2+) uptake did not change. The percentage of myosin heavy chain IIx isoform was decreased significantly after training. At the whole muscle level, neither central activation nor maximum voluntary isometric contraction force were significantly altered, although isometric force did exhibit a trend toward an increase (~3%, P = 0.055). Surprisingly, the NMES training produced a significant increase in muscle cross-sectional area (~3%, P = 0.04). It seems that an appropriately designed NMES protocol can mimic many of the benefits of sprint exercise training, with a low overall time commitment and training volume. These findings suggest that NMES has the potential to bring the benefits of sprint exercise to individuals who are unable to tolerate traditional sprint training.

Gaps in the Substance Use Disorder Treatment Referral Process: Provider Perceptions.

PubMed

Blevins, Claire E; Rawat, Nishi; Stein, Michael D

2018-05-07

The demand for substance use disorder treatment is increasing, fueled by the opioid epidemic and the Affordable Care Act mandate to treat substance use disorders. The increased demand for treatment, however, is not being met by a corresponding increase in access to or availability of treatment. This report focuses specifically on the treatment referral process, which we have identified as 1 of the key barriers to timely and effective treatment. Difficulties in referral to substance use disorder treatment are examined through the lens of providers who make referrals (ie, referral source) and individuals who work in substance use disorder facilities (ie, referral recipient). Administrative officials, emergency department physicians, addiction physicians, government officials, providers, insurance officials, and mental health advocates (n = 59) were interviewed on the referral process protocol, challenges for providers and others making referrals, and issues with substance use treatment facility intake procedures. Several main themes were identified as barriers in the process: difficulties in determining patient eligibility, lack of transparency regarding treatment capacity, referral source knowledge/understanding of options, and issues with communication between referral source and recipient. We then proposed several solutions to address specific barriers. Current gaps in the referral process cause delays to care. Improving systems would involve addressing these themes and expanding the use of appropriate treatments for the many patients in need.

Optimized in vivo detection of dopamine release using 18F-fallypride PET.

PubMed

Ceccarini, Jenny; Vrieze, Elske; Koole, Michel; Muylle, Tom; Bormans, Guy; Claes, Stephan; Van Laere, Koen

2012-10-01

The high-affinity D(2/3) PET radioligand (18)F-fallypride offers the possibility of measuring both striatal and extrastriatal dopamine release during activation paradigms. When a single (18)F-fallypride scanning protocol is used, task timing is critical to the ability to explore both striatal and extrastriatal dopamine release simultaneously. We evaluated the sensitivity and optimal timing of task administration for a single (18)F-fallypride PET protocol and the linearized simplified reference region kinetic model in detecting both striatal and extrastriatal reward-induced dopamine release, using human and simulation studies. Ten healthy volunteers underwent a single-bolus (18)F-fallypride PET protocol. A reward responsiveness learning task was initiated at 100 min after injection. PET data were analyzed using the linearized simplified reference region model, which accounts for time-dependent changes in (18)F-fallypride displacement. Voxel-based statistical maps, reflecting task-induced D(2/3) ligand displacement, and volume-of-interest-based analysis were performed to localize areas with increased ligand displacement after task initiation, thought to be proportional to changes in endogenous dopamine release (γ parameter). Simulated time-activity curves for baseline and hypothetical dopamine release functions (different peak heights of dopamine and task timings) were generated using the enhanced receptor-binding kinetic model to investigate γ as a function of these parameters. The reward task induced increased ligand displacement in extrastriatal regions of the reward circuit, including the medial orbitofrontal cortex, ventromedial prefrontal cortex, and dorsal anterior cingulate cortex. For task timing of 100 min, ligand displacement was found for the striatum only when peak height of dopamine was greater than 240 nM, whereas for frontal regions, γ was always positive for all task timings and peak heights of dopamine. Simulation results for a peak height of dopamine of 200 nM showed that an effect of striatal ligand displacement could be detected only when task timing was greater than 120 min. The prefrontal and anterior cingulate cortices are involved in reward responsiveness that can be measured using (18)F-fallypride PET in a single scanning session. To measure both striatal and extrastriatal dopamine release, the height of dopamine released and task timing need to be considered in designing activation studies depending on regional D(2/3) density.

Emulation of Industrial Control Field Device Protocols

DTIC Science & Technology

2013-03-01

platforms such as the Arduino ( based on the Atmel AVR architecture) or popular PIC architecture based devices, which are programmed for specific functions...UNIVERSITY AIR FORCE INSTITUTE OF TECHNOLOGY Wright-Patterson Air Force Base , Ohio DISTRIBUTION STATEMENT A. APPROVED FOR PUBLIC RELEASE; DISTRIBUTION...confidence intervals for the mean. Based on these results, extensive knowledge of the specific implementations of the protocols or timing profiles of the

Japan-U.S. Relations: Issues for Congress

DTIC Science & Technology

2009-06-03

resentful of Japan’s occupation policies and aggression in the World War II period. Despite underlying distrust, Tokyo’s relationships with Beijing and...prisoners during World War II, a charge that was later confirmed by the release of government documents. China In concert with the leadership in Beijing ...earthquake rescue experts then were dispatched to the hard-hit Sichuan province, the first foreign team that Beijing accepted. The official

Treatment of Laser-Induced Retinal Injury and Visual Loss Using Sustained Release of Intra-Vitreal Neurotrophic Growth Factors. Addendum

DTIC Science & Technology

2011-11-01

REPORT DATE: TYPE OF REPORT: PREPARED FOR: U.S. Army Medical Research and...construed as an official Department of the Army position, policy or decision unless so designated by other documentation. REPORT DOCUMENTATION...SPONSORING / MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) U.S. Army Medical Research and Materiel Command Fort Detrick

Copyright: 1971-1981.

DTIC Science & Technology

1982-01-01

mark; whereas the best-selling writer, with a package of rights for sale to film , tele- vision, etc., may have more concern over national taxation... Rights Reserved ISBN 92-835-1411-4 Printed by Technical Editing and Reproduction Ltd Harford Houe, 7-9 Charlotte St. London, WIP IHD Hi CONTENTS Page...officially released anywhere else. And certainly the record publishers, and more recently the film and video industry, have much cause for complaint

Low Frequency Acoustic Intensity Propagation Modeling in Shallow Water Waveguides

DTIC Science & Technology

2016-06-01

REPORT NUMBER 11. SUPPLEMENTARY NOTES The views expressed in this thesis are those of the author and do not reflect the official policy or position of...release; distribution is unlimited 12b. DISTRIBUTION CODE A 13. ABSTRACT (maximum 200 words) Three popular numerical techniques are employed to...planar interfacial two-fluid transmission and reflection are used to benchmark the commercial software package COMSOL. Canonical Pekeris-type

Dealing with the Quaternion Antipodal Problem for Advecting Fields

DTIC Science & Technology

2017-12-01

public release; distribution is unlimited. NOTICES Disclaimers The findings in this report are not to be construed as an official Department of the Army...primary author’s email: <richard.c.becker.civ@mail.mil>. Quaternion representations of rotations are proposed for advecting rotations in large strain...products of quaternions to ameliorate these issues. The results of both are unique and continuous, but the former does not capture the correct

An Investigation Into Ventilation And Dust Issues For The Joint Light Tactical Vehicle (JLTV)

DTIC Science & Technology

2012-05-01

testing at Yuma and other places, the JLTV is filling up with dust and people are having a difficult time seeing and breathing. Obviously, a bad ...2012 Approved for public release; distribution is unlimited. NOTICES Disclaimers The...Citation of manufacturer’s or trade names does not constitute an official endorsement or approval of the use thereof. Destroy this report when it is

Verification and Validation of Rural Propagation in the Sage 2.0 Simulation

DTIC Science & Technology

2016-08-01

position unless so designated by other authorized documents. Citation of manufacturer’s or trade names does not constitute an official endorsement or...Approved for public release; distribution unlimited. 1 1. Introduction The System of Systems Survivability Simulation (S4) is designed to be...materiel developers. The Sage model, part of the S4 simulation suite, has been developed primarily to support SLAD analysts in pretest planning and

Androgen Receptor-Mediated Escape Mechanisms from Androgen Ablation Therapy

DTIC Science & Technology

2005-10-01

intestinal polyps, the precursor of invasive carcinoma and colon cancer. Also, fain-of-function, truncated forms of 3-catenin occurring in metastatic prostate...STATEMENT: Approved for Public Release; Distribution Unlimited The views, opinions and/or findings contained in this report are those of the author(s) and...should not be construed as an official Department of the Army position, policy or decision unless so designated by other documentation. 20060503040

Novel Approaches to Locoregional and Systemic Immunotherapy for Ovarian Cancer

DTIC Science & Technology

2017-10-01

Dmitriy Zamarin CONTRACTING ORGANIZATION: Memorial Sloan Kettering Cancer Center New York, NY 10017 REPORT DATE: October 2017 TYPE OF REPORT ...Public Release; Distribution Unlimited The views, opinions and/or findings contained in this report are those of the author(s) and should not be...construed as an official Department of the Army position, policy or decision unless so designated by other documentation. REPORT DOCUMENTATION PAGE Form

Department of Defense HIV/AIDS Prevention Program (DHAPP), 2012

DTIC Science & Technology

2013-06-04

reflect the official policy or position of the Department of the Navy, Department of Defense, nor the U. S. Government . Approved for public release...157 Bahamas, The 159 Barbados 161 Belize 163 Bolivia 166 Colombia 168 Dominican Republic 171 Ecuador 174 El Salvador 176 Guatemala 179... Government USMHRP – US Military HIV Research Program USPACOM – US Pacific Command USSOUTHCOM – US Southern Command VMMC - voluntary medical male

Improved Training Program for Fall Prevention of Warfighters with Lower Extremity Trauma

DTIC Science & Technology

2017-10-01

INVESTIGATOR: Kenton Kaufman, PhD, PE CONTRACTING ORGANIZATION: Mayo Clinic Rochester, MN 55905 REPORT DATE: October 2017 TYPE OF REPORT : Annual...Release; Distribution Unlimited The views, opinions and/or findings contained in this report are those of the author(s) and should not be construed...as an official Department of the Army position, policy or decision unless so designated by other documentation. REPORT DOCUMENTATION PAGE Form

Simplified dispatch-assisted CPR instructions outperform standard protocol.

PubMed

Dias, J A; Brown, T B; Saini, D; Shah, R C; Cofield, S S; Waterbor, J W; Funkhouser, E; Terndrup, T E

2007-01-01

Dispatch-assisted chest compressions only CPR (CC-CPR) has gained widespread acceptance, and recent research suggests that increasing the proportion of compression time during CPR may increase survival from out-of-hospital cardiac arrest. We created a simplified CC-CPR protocol to reduce time to start chest compressions and to increase the proportion of time spent delivering chest compressions. This simplified protocol was compared to a published protocol, Medical Priority Dispatch System (MPDS) Version 11.2, recommended by the National Academies of Emergency Dispatch. Subjects were randomized to the MPDS v11.2 protocol or a simplified protocol. Data was recorded from a Laerdal Resusci Anne Skillreporter manikin. A simulated emergency medical dispatcher, contacted by cell phone, delivered standardized instructions for both protocols. Outcomes included chest compression rate, depth, hand position, full release, overall proportion of compressions without error, time to start of CPR and total hands-off chest time. Proportions were analyzed by Wilcoxon's Rank Sum tests and time variables with Welch ANOVA and Wilcoxon's Rank Sum test. All tests used a two-sided alpha-level of 0.05. One hundred and seventeen subjects were randomized prospectively, 58 to the standard protocol and 59 to the simplified protocol. The average age of subjects in both groups was 25 years old. For both groups, the compression rate was equivalent (104 simplified versus 94 MPDS, p = 0.13), as was the proportion with total release (1.0 simplified versus 1.0 MPDS, p = 0.09). The proportion to the correct depth was greater in the simplified protocol (0.31 versus 0.03, p < 0.01), as was the proportion of compressions done without error (0.05 versus 0.0, p = 0.16). Time to start of chest compressions and total hands-off chest time were better in the simplified protocol (start time 60.9s versus 78.6s, p < 0.0001; hands-off chest time 69 s versus 95 s, p < 0.0001). The proportion with correct hand position, however, was worse in the simplified protocol (0.35 versus 0.84, p < 0.01). The simplified protocol was as good as, or better than the MPDS v11.2 protocol in every aspect studied except hand position, and the simplified protocol resulted in significant time savings. The protocol may need modification to ensure correct hand position. Time savings and improved quality of CPR achieved by the new set of instructions could be important in strengthening critical links in the cardiac chain of survival.

Transition Metal Free C-N Bond Forming Dearomatizations and Aryl C-H Aminations by in Situ Release of a Hydroxylamine-Based Aminating Agent.

PubMed

Farndon, Joshua J; Ma, Xiaofeng; Bower, John F

2017-10-11

We outline a simple protocol that accesses directly unprotected secondary amines by intramolecular C-N bond forming dearomatization or aryl C-H amination. The method is dependent on the generation of a potent electrophilic aminating agent released by in situ deprotection of O-Ts activated N-Boc hydroxylamines.

Highly Absorbing Metal Nanolaminates for Bi-Material THz Sensors

DTIC Science & Technology

2011-09-01

NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA THESIS Approved for public release; distribution is unlimited HIGHLY ABSORBING...Prescribed by ANSI Std. 239-18 REPORT DOCUMENTATION PAGE Form Approved OMB No. 0704-0188 Public reporting burden for this collection of information is...Government. IRB Protocol number: N/A. 12a. DISTRIBUTION / AVAILABILITY STATEMENT Approved for public release; distribution is unlimited 12b

Understanding Internal Accountability in Nigeria’s Routine Immunization System: Perspectives From Government Officials at the National, State, and Local Levels

PubMed Central

Erchick, Daniel J.; George, Asha S.; Umeh, Chukwunonso; Wonodi, Chizoba

2017-01-01

Background: Routine immunization coverage in Nigeria has remained low, and studies have identified a lack of accountability as a barrier to high performance in the immunization system. Accountability lies at the heart of various health systems strengthening efforts recently launched in Nigeria, including those related to immunization. Our aim was to understand the views of health officials on the accountability challenges hindering immunization service delivery at various levels of government. Methods: A semi-structured questionnaire was used to interview immunization and primary healthcare (PHC) officials from national, state, local, and health facility levels in Niger State in north central Nigeria. Individuals were selected to represent a range of roles and responsibilities in the immunization system. The questionnaire explored concepts related to internal accountability using a framework that organizes accountability into three axes based upon how they drive change in the health system. Results: Respondents highlighted accountability challenges across multiple components of the immunization system, including vaccine availability, financing, logistics, human resources, and data management. A major focus was the lack of clear roles and responsibilities both within institutions and between levels of government. Delays in funding, especially at lower levels of government, disrupted service delivery. Supervision occurred less frequently than necessary, and the limited decision space of managers prevented problems from being resolved. Motivation was affected by the inability of officials to fulfill their responsibilities. Officials posited numerous suggestions to improve accountability, including clarifying roles and responsibilities, ensuring timely release of funding, and formalizing processes for supervision, problem solving, and data reporting. Conclusion: Weak accountability presents a significant barrier to performance of the routine immunization system and high immunization coverage in Nigeria. As one stakeholder in ensuring the performance of health systems, routine immunization officials reveal critical areas that need to be prioritized if emerging interventions to improve accountability in routine immunization are to have an effect. PMID:28812836

The GLOBE/Madagascar Malaria Project: Creating Student/Educator/Scientist Partnerships With Regional Impact

NASA Astrophysics Data System (ADS)

Brooks, D.; Boger, R.; Rafalimanana, A.

2006-05-01

Malaria is a parasitic disease spread by mosquitoes in the genus Anopheles. It causes more than 300,000,000 acute illnesses and more than one million deaths annually, including the death of one African child every 30 seconds. Recent epidemiological trends include increases in malaria mortality and the emergence of drug-resistant parasites. Some experts believe that predicted climate changes during the 21st century will bring malaria to areas where it is not now common. The GLOBE Program is currently collaborating with students, educators, scientists, health department officials, and government officials in Madagascar to develop a program that combines existing GLOBE protocols for measuring atmospheric and water quality parameters with a new protocol for collecting and identifying mosquito larvae at the genus (Anopheles and non-Anopheles) level. There are dozens of Anopheles species and sub-species that are adapted to a wide range of micro-environmental conditions encountered in Madagascar's variable climate. Local data collection is essential because mosquitoes typically spend their entire lives within a few kilometers of their breeding sites. The GLOBE Program provides an ideal framework for such a project because it offers a highly structured system for defining experiment protocols that ensure consistent procedures, a widely dispersed network of observing sites, and a centralized data collection and reporting system. Following a series of training activities in 2005, students in Madagascar are now beginning to collect data. Basic environmental parameters and first attempts at larvae collection and identification are presented. Results from this project can be used to increase public awareness of malaria, to provide new scientific data concerning environmental impacts on mosquito breeding, and to provide better information for guiding effective mitigation strategies. Problems encountered include difficulties in visiting and communicating with remote school sites. These are typical problems in developing tropical countries where malaria is endemic and their solution benefits the entire scientific and educational infrastructure in those countries.

A systematic review of postoperative hand therapy management of basal joint arthritis.

PubMed

Wolfe, Terri; Chu, Jennifer Y; Woods, Tammy; Lubahn, John D

2014-04-01

There are a variety of postoperative immobilization and therapy options for patients with basal joint arthritis. Although prior systematic reviews have compared surgical procedures used to treat basal joint arthritis, none to our knowledge compares therapy protocols for this condition, which are considered an important part of the treatment. (1) We sought to determine whether differences in the length and type of postoperative immobilization affect clinical results after basal joint arthritis surgery. (2) We also compared specific therapy protocols that were prescribed. (3) Finally, we evaluated published protocols to determine when patients were released to full activity to see whether these appeared to affect clinical results. A systematic review of English-language studies in the PubMed and Cochrane databases was performed. Studies were then reviewed to determine what postoperative immobilization and therapy protocols the authors used and when patients were released to full activities. A total of 19 studies were identified using the search criteria. All but one of the studies included a postoperative period of immobilization in either a cast or splint. Immobilization time varied depending on whether Kirschner wires were used for the surgery and whether an implant was placed. Postoperative therapy protocols also varied but followed three general patterns. Some therapy protocols involved teaching patients a home exercise program only, whereas some authors described routine referral to a therapist. The third group consisted of studies in which patients were only referred for therapy if the physicians determined it was necessary during followup. Many studies did not give a specific time for full return to activity and instead described a gradual transition to full activity after immobilization was discontinued. Because of the variability and small numbers, no conclusive recommendations could be made on any of the three study questions. Comparative, multicenter studies comparing different immobilization and therapy protocols after the surgical treatment of basal joint arthritis would be helpful for both surgeons and therapists looking to refine their treatment protocols.

A Communication Protocol for CyAMS and the Cyber Fighter Associate Interface

DTIC Science & Technology

2015-05-01

by David Harman , Scott Brown, Brian Henz, and Lisa M Marvel Approved for public release; distribution unlimited...Laboratory A Communication Protocol for CyAMS and the Cyber Fighter Associate Interface by David Harman College Qualified Leaders Student...CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) David Harman , Scott Brown, Brian Henz, and Lisa M Marvel 5d. PROJECT

State Summary of Soil and Groundwater Cleanup Standards for Hydrocarbons

DTIC Science & Technology

1993-11-15

821096-01 November 15, 1993 19970425 057 !DISTfRIBUTI STýA-TEM,_ Approved for public release; Distribution Unlbfited Product - Paranmeter/ Lab Test ...Env-mmenal Mantagemen, 20-270-5613 Product Parameter/ Lab Test Protocol Detection Notification Action Clean-up Level Constituent & Number Level Level...Envi-mnentai Managament, 205-270-.5613 Su m r of Alsk Clanu Sadr s fo Hyrcro Cotmiae Groundwater Product- - Parameter/ Lab Test Protocol ’Detection

The Ideals of Today’s Modernizing People’s Liberation Army

DTIC Science & Technology

2010-06-01

Government. IRB Protocol number ___N/A_____________. 12a. DISTRIBUTION / AVAILABILITY STATEMENT Approved for public release; distribution is unlimited...was a tutor and teacher for the children of the de facto ruler of Lu, Meng Xizi, where he taught ritual etiquette observed at state religious...appropriately to one’s circumstances and role. One must observe the proper rituals, ceremonies, and protocols to promote social cohesion and individual

Extension of the validation of AOAC Official Method 2005.06 for dc-GTX2,3: interlaboratory study.

PubMed

Ben-Gigirey, Begoña; Rodríguez-Velasco, María L; Gago-Martínez, Ana

2012-01-01

AOAC Official Method(SM) 2005.06 for the determination of saxitoxin (STX)-group toxins in shellfish by LC with fluorescence detection with precolumn oxidation was previously validated and adopted First Action following a collaborative study. However, the method was not validated for all key STX-group toxins, and procedures to quantify some of them were not provided. With more STX-group toxin standards commercially available and modifications to procedures, it was possible to overcome some of these difficulties. The European Union Reference Laboratory for Marine Biotoxins conducted an interlaboratory exercise to extend AOAC Official Method 2005.06 validation for dc-GTX2,3 and to compile precision data for several STX-group toxins. This paper reports the study design and the results obtained. The performance characteristics for dc-GTX2,3 (intralaboratory and interlaboratory precision, recovery, and theoretical quantification limit) were evaluated. The mean recoveries obtained for dc-GTX2,3 were, in general, low (53.1-58.6%). The RSD for reproducibility (RSD(r)%) for dc-GTX2,3 in all samples ranged from 28.2 to 45.7%, and HorRat values ranged from 1.5 to 2.8. The article also describes a hydrolysis protocol to convert GTX6 to NEO, which has been proven to be useful for the quantification of GTX6 while the GTX6 standard is not available. The performance of the participant laboratories in the application of this method was compared with that obtained from the original collaborative study of the method. Intralaboratory and interlaboratory precision data for several STX-group toxins, including dc-NEO and GTX6, are reported here. This study can be useful for those laboratories determining STX-group toxins to fully implement AOAC Official Method 2005.06 for official paralytic shellfish poisoning control. However the overall quantitative performance obtained with the method was poor for certain toxins.

Implications Of The Security Cooperation Office Transition in Afghanistan For Special Operations Forces: An Abbreviated Report of the Study’s Primary Findings

DTIC Science & Technology

2017-01-01

for working in an interagency environment can lead to mission success. From the Iraq case study , one former U.S. Forces–Iraq official felt that...of six historical case studies in which the mission of special operations forces (SOF) in country transitioned over time to some level of inclusion...explanation of the methodology applied for case study selec- tion, as well as adopted interview protocols, are provided in the long- form version of

Confocal Raman Microspectroscopy: The Measurement of VX Depth Profiles in Hairless Guinea Pig Skin and the Evaluation of RSDL

DTIC Science & Technology

2015-02-01

Defense, or the U.S. Government. The experimental protocol was approved by the Animal Care and Use Committee at the United States Army Medical Research...Laboratory Animals and the Animal Welfare Act of 1966 (P.L. 89-544), as amended. The use of trade names does not constitute an official endorsement or...neat VX (0.3 µl, 13-14 x LD50), using a specially designed template that allowed repeated Raman measurements on the same skin location. Animals were

In situ green synthesis of antimicrobial carboxymethyl chitosan-nanosilver hybrids with controlled silver release.

PubMed

Huang, Siqi; Yu, Zhiming; Zhang, Yang; Qi, Chusheng; Zhang, Shifeng

2017-01-01

In order to fabricate antimicrobial carboxymethyl chitosan-nanosilver (CMC-Ag) hybrids with controlled silver release, this study demonstrated comparable formation via three synthetic protocols: 1) carboxymethyl chitosan (CMC) and glucose (adding glucose after AgNO 3 ), 2) CMC and glucose (adding glucose before AgNO 3 ), and 3) CMC only. Under principles of green chemistry, the synthesis was conducted in an aqueous medium exposed to microwave irradiation for 10 minutes with nontoxic chemicals. The structure and formation mechanisms of the three CMC-Ag hybrids were explored using X-ray diffraction, ultraviolet-visible spectroscopy, transmission electron microscopy, and Fourier-transform infrared analyses. Additionally, antimicrobial activity and in vitro silver release of the three synthesized hybrids were investigated in detail. The results revealed that a large number of stable, uniform, and small silver nanoparticles (AgNPs) were synthesized in situ on CMC chains via protocol 1. AgNPs were well dispersed with narrow size distribution in the range of 6-20 nm, with mean diameter only 12.22±2.57 nm. The addition of glucose resulted in greater AgNP synthesis. The order of addition of glucose and AgNO 3 significantly affected particle size and size distribution of AgNPs. Compared to CMC alone and commercially available AgNPs, the antimicrobial activities of three hybrids were significantly improved. Of the three hybrids, CMC-Ag1 synthesized via protocol 1 exhibited better antimicrobial activity than CMC-Ag2 and CMC-Ag3, and showed more effective inhibition of Staphylococcus aureus than Escherichia coli . Due to strong coordination and electrostatic interactions between CMC and silver and good steric protection provided by CMC, CMC-Ag1 displayed stable and continuous silver release and better performance in retaining silver for prolonged periods than CMC-Ag2 and CMC-Ag3.

Alcohol, Aldehyde, and Ketone Liberation and Intracellular Cargo Release through Peroxide-Mediated α-Boryl Ether Fragmentation.

PubMed

Hanna, Ramsey D; Naro, Yuta; Deiters, Alexander; Floreancig, Paul E

2016-10-12

α-Boryl ethers, carbonates, and acetals, readily prepared from the corresponding alcohols that are accessed through ketone diboration, react rapidly with hydrogen peroxide to release alcohols, aldehydes, and ketones through the collapse of hemiacetal intermediates. Experiments with α-boryl acetals containing a latent fluorophore clearly demonstrate that cargo can be released inside cells in the presence of exogenous or endogenous hydrogen peroxide. These experiments show that this protocol can be used for drug activation in an oxidative environment without generating toxic byproducts.

Robust Satellite Communications Under Hostile Interference

DTIC Science & Technology

2016-05-20

Kirtland AFB, NM 87117-5776 AFRL /RVSW 11. SPONSOR/MONITOR’S REPORT NUMBER(S) AFRL -RV-PS-TR-2016-0079 12. DISTRIBUTION / AVAILABILITY STATEMENT...22060-6218 1 cy AFRL /RVIL Kirtland AFB, NM 87117-5776 2 cys Official Record Copy AFRL /RVSW/Khanh Pham 1 cy 28 Approved for public release... AFRL -RV-PS- AFRL -RV-PS- TR-2016-0079 TR-2016-0079 ROBUST SATELLITE COMMUNICATIONS UNDER HOSTILE INTERFERENCE Marc Lichtman and Jeffrey Reed

The Benefits of Completing Homework for Students with Different Aptitudes in an Introductory Electricity and Magnetism Course

DTIC Science & Technology

2015-02-17

this study, course exams were used to measure student learning rather than research -based concept tests like the Force Concept Inventory [ 19), the...Release Information: This art icles has been accepted by Physical Review Special Topics -- Physics Education Research fo r publication. Previous...portraying official policy. II signed // MONTE D. ANDERSON, Lt Col, USAF Deputy Department Head for Research Department of Physics Tabs 1

Urban Terrain Building Types: Second Edition Public Releasable Version

DTIC Science & Technology

2012-11-01

in this report are not to be construed as an official Department of the Army position unless so designated by other authorized documents...longer needed. Do not return it to the originator. Army Research Laboratory Aberdeen Proving Ground, MD 21005-5067 ARL-TR-4395a November 2012...ADDRESS(ES) U.S. Army Research Laboratory ATTN: AMSRD-ARL-SL-BA Aberdeen Proving Ground, MD 21005-5067 10. SPONSOR/MONITOR’S ACRONYM(S) 11

Outcomes from the First Wingman Software in the Loop Integration Event: January 2017

DTIC Science & Technology

2017-06-28

for public release; distribution is unlimited. NOTICES Disclaimers The findings in this report are not to be construed as an official...and enhance communication among manned‐unmanned team members, which are critical to achieve Training and Doctrine Command 6+1 required capabilities...Computers to Run the SIL 10 4.1.2 Problem 2: Computer Networking 10 4.1.3 Problem 3: Installation of ARES 11 4.2 Developing Matching Virtual

TRAF4 and Castration-Resistant Prostate Cancer

DTIC Science & Technology

2017-10-01

opinions and/or findings contained in this report are those of the author(s) and should not be construed as an official Department of the Army position...AVAILABILITY STATEMENT Approved for Public Release; Distribution Unlimited 13. SUPPLEMENTARY NOTES 14. ABSTRACT It is now well-recognized that AR remains...to be a critical player in castration-resistant prostate cancers. It was suggested that the function of AR in CRPC is not to turn on the same

Regulation of Breast Cancer Stem Cell by Tissue Rigidity

DTIC Science & Technology

2015-06-01

analysis. The TCGA breast cancer gene expression data set (TCGA BRCA G4502A_07_3) was downloaded from the UCSC Cancer Genome Browser (https:// genome ...Public Release; Distribution Unlimited The views, opinions and/or findings contained in this report are those of the author(s) and should not be...construed as an official Department of the Army position, policy or decision unless so designated by other documentation. Report Documentation Page Form

Naked DNA Immunization of Prevention of Prostate Cancer in a Dunning Rat Prostate Tumor Model

DTIC Science & Technology

2006-06-01

is performed by use of the BCA protein test. 6 Bioburden assay (for DNA of a final concentration not more than 1 mg/ml); 1 colonies following United...the policy of the Government, and no official endorsement should be inferred. For purpose of this article , information includes news releases... articles , manuscripts, brochures, advertisements, still and motion pictures, speeches, trade association proceedings etc. ABSTRACT The ability of

Aortic Hemostasis and Resuscitation Advanced REBOA for NCTH and Reversal of HiTCA

DTIC Science & Technology

2017-06-01

James D Ross, PhD CONTRACTING ORGANIZATION: Oregon Health & Science University Portland, OR 97239 REPORT DATE: JUNE 2017 TYPE OF REPORT ...Public Release; Distribution Unlimited The views, opinions and/or findings contained in this report are those of the author(s) and should not be...construed as an official Department of the Army position, policy or decision unless so designated by other documentation. 2 REPORT DOCUMENTATION PAGE

Sustainability of Colombian Military/Strategic Support for Democratic Security

DTIC Science & Technology

2005-07-01

Other portions of the text were presented on February 23, 2005, in Bogota at a Fundacion conference, " Sostenibilidad de la Seguridad Democratica...Unlimited Thomas A. Marks July 2005 20050805 010 The views expressed in this report are those of the author and do not necessarily reflect the...official policy or position of the Department of the Army, the Department of Defense, or the U.S. Government. This report is cleared for public release

Treaty to Curb Mercury Pollution Adopted

NASA Astrophysics Data System (ADS)

Showstack, Randy

2013-10-01

The international Minamata Convention on Mercury to protect human health and the environment from anthropogenic emissions and releases of mercury and mercury compounds was formally adopted at a 10 October meeting in Minamata, Japan. The legally binding treaty, currently signed by 92 countries, comes 57 years after the government of Japan officially acknowledged, in 1956, the existence of Minamata disease, which was caused by eating seafood contaminated with methylmercury compounds discharged into Minamata Bay in southern Japan.

U.S. Policy Options for Iraq: A Reassessment

DTIC Science & Technology

2007-01-01

República de Colombia, “ Gobierno Reglamento Ley de ‘Justicia y Paz,’” press release, Bogotá, January 2, 2006. Castaneda, Antonio, “Iraqi Army Struggles...Units with records of abuse should be disbanded. Individuals complicit in abuse, including high-level officials and those tied to them, must be...respondents described security as poor.5 Because of the prevalence of violence, Iraqi adults restrict their activi- ties , children are kept home from school

Mechanistic Modeling of the Effects of Acidosis on Thrombin Generation

DTIC Science & Technology

2015-08-01

Telemedicine and Advanced Technology Research Center; U.S. Army Medical Research and Materiel Command, Ft. Detrick, MD; and Departments of...are the private views of the authors and are not to be construed as official or as reflecting the views of the U.S. Army or of the U.S. Department ...of Defense . This paper has been approved for public release with unlimited distribution. Reprints will not be available from the authors. Address

An Evaluation of the Generalized Intelligent Framework for Tutoring (GIFT) from an Author’s Perspective

DTIC Science & Technology

2014-12-01

group instruction as effective as one - to- one tutoring. Educational Researcher. 1984;13(6):4–16. Carbonell. AI in CAI: an artificial intelligence...an official Department of the Army position unless so designated by other authorized documents. Citation of manufacturer’s or trade names does...public release; distribution is unlimited. 13. SUPPLEMENTARY NOTES 14. ABSTRACT Current US Army standards for training and education are group

Preclinical Evaluation of the Effects of Aeromedical Evacuation on Military-Relevant Casualties

DTIC Science & Technology

2017-10-01

PRINCIPAL INVESTIGATOR: Dr. Richard McCarron RECIPIENT: Naval Medical Research Center Silver Spring, MD 20910 REPORT DATE: October 2017 TYPE OF REPORT ...public release; distribution is unlimited. The views, opinions and/or findings contained in this report are those of the author(s) and should not be...construed as an official Department of the Army position, policy or decision unless so designated by other documentation. REPORT DOCUMENTATION PAGE

Testing a Low-Interaction Honeypot against Live Cyber Attackers

DTIC Science & Technology

2011-09-01

to run Snort were the Sourcefire Vulnerability Research Team ( VRT ) rules, which are the official rules available for the program. We used the...latest VRT rules that were available free to registered users, rules an average of 30 days old when released. The software provides a detailed alert log...although it is production system. On the Windows machine we installed Snort 2.9 with the VRT rules. Snort was configured to log comma-separated

Preparing Federal Coordinating Officers (FCOs) to Operate in Chemical, Biological, Radiological, and Nuclear (CBRN) Environments

DTIC Science & Technology

2008-12-01

Coordination Center RDD--Radiological Dispersal Device TOP OFF--Top Officials Exercise TQP--Tiered Qualifications Plan UC--Unified Command UCG ...National Press Club, Release No. FNF-06- 019, November 30, 2006. 101 W. Chan Kim and Renee Mauborgne, Blue Ocean Strategy: How to Create Uncontested Market ...Ask Open Ended Questions,” Evan Carmichael, http://www.evancarmichael.com/ marketing /80/ask-open-ended-questions.html (accessed on September 21, 2008

The do-not-resuscitate order in teaching hospitals.

PubMed

Evans, A L; Brody, B A

1985-04-19

We studied the use of do-not-resuscitate (DNR) orders at three teaching hospitals that did not have official protocols for such orders to see whether their use meets the goals (decision making before a crisis and promoting patient autonomy) that have been identified for such orders. We found that 20% of all patients had or were being considered for DNR orders, that the patient and/or family was usually involved (83%) in the decision not to resuscitate, but rarely involved (25%) in decisions to resuscitate, or in cases of no decision, that a wide range of care was provided to patients with a DNR status, and that partial resuscitative efforts would be employed in some cases. Our main conclusion in light of our findings is that DNR orders are currently not fulfilling their major goals. We offer six proposals for improving future DNR protocols.

The relationship between Q gamma and Ca release from the sarcoplasmic reticulum in skeletal muscle

PubMed Central

1991-01-01

Asymmetric membrane currents and fluxes of Ca2+ release were determined in skeletal muscle fibers voltage clamped in a Vaseline-gap chamber. The conditioning pulse protocol 1 for suppressing Ca2+ release and the "hump" component of charge movement current (I gamma), described in the first paper of this series, was applied at different test pulse voltages. The amplitude of the current suppressed during the ON transient reached a maximum at slightly suprathreshold test voltages (- 50 to -40 mV) and decayed at higher voltages. The component of charge movement current suppressed by 20 microM tetracaine also went through a maximum at low pulse voltages. This anomalous voltage dependence is thus a property of I gamma, defined by either the conditioning protocol or the tetracaine effect. A negative (inward-going) phase was often observed in the asymmetric current during the ON of depolarizing pulses. This inward phase was shown to be an intramembranous charge movement based on (a) its presence in the records of total membrane current, (b) its voltage dependence, with a maximum at slightly suprathreshold voltages, (c) its association with a "hump" in the asymmetric current, (d) its inhibition by interventions that reduce the "hump", (e) equality of ON and OFF areas in the records of asymmetric current presenting this inward phase, and (f) its kinetic relationship with the time derivative of Ca release flux. The nonmonotonic voltage dependence of the amplitude of the hump and the possibility of an inward phase of intramembranous charge movement are used as the main criteria in the quantitative testing of a specific model. According to this model, released Ca2+ binds to negatively charged sites on the myoplasmic face of the voltage sensor and increases the local transmembrane potential, thus driving additional charge movement (the hump). This model successfully predicts the anomalous voltage dependence and all the kinetic properties of I gamma described in the previous papers. It also accounts for the inward phase in total asymmetric current and in the current suppressed by protocol 1. According to this model, I gamma accompanies activating transitions at the same set of voltage sensors as I beta. Therefore it should open additional release channels, which in turn should cause more I gamma, providing a positive feedback mechanism in the regulation of calcium release. PMID:1650812

Human rights and mass disaster: lessons from the 2004 tsunami.

PubMed

Weinstein, H M; Fletcher, L E; Stover, E

2007-01-01

This paper describes the results of an investigation into how the December, 2004 tsunami and its aftermath affected the human rights of the survivors. Teams of researchers interviewed survivors, government officials, representatives of international and local nongovernmental organisations, UN officials, the military, police, and other key informants in India, Sri Lanka, the Maldives, Indonesia, and Thailand. We also analysed newspaper articles, reports released by governments, UN agencies, NGOs, and private humanitarian aid groups, and we examined the laws and policies related to survivors' welfare in the affected countries. We found worsening of prior human rights violations, inequities in aid distribution, lack of accountability and impunity, poor coordination of aid, lack of community participation in reconstruction, including coastal redevelopment. Corruption and preexisting conflict negatively impact humanitarian interventions. We make recommendations to international agencies, states, and local health service providers. A human rights framework offers significant protection to survivors and should play a critical role in disaster response.

Data Release: DNA barcodes of plant species collected for the Global Genome Initiative for Gardens Program, National Museum of Natural History, Smithsonian Institution

PubMed Central

Zúñiga, Jose D.; Gostel, Morgan R.; Mulcahy, Daniel G.; Barker, Katharine; Asia Hill; Sedaghatpour, Maryam; Vo, Samantha Q.; Funk, Vicki A.; Coddington, Jonathan A.

2017-01-01

Abstract The Global Genome Initiative has sequenced and released 1961 DNA barcodes for genetic samples obtained as part of the Global Genome Initiative for Gardens Program. The dataset includes barcodes for 29 plant families and 309 genera that did not have sequences flagged as barcodes in GenBank and sequences from officially recognized barcoding genetic markers meet the data standard of the Consortium for the Barcode of Life. The genetic samples were deposited in the Smithsonian Institution’s National Museum of Natural History Biorepository and their records were made public through the Global Genome Biodiversity Network’s portal. The DNA barcodes are now available on GenBank. PMID:29118648

Influence of formulation technique on acrylate methacrylate copolymer modified paracetamol matrix tablets.

PubMed

Cash-Torunarigha, Omonyemen Edoise; Eichie, Florence Egbomonjiade; Arhewoh, Matthew Ikhuoria

2015-03-01

This work was designed to evaluate the influence of various methods such as dry granulation (DG), wet granulation (using the polymer in an ethanolic solution (WGO) or aqueous dispersion (WGA) and solid dispersion (SD) techniques, on properties of paracetamol matrix tablets prepared using varying concentrations of acrylate methacrylate copolymer. Tablet properties were investigated using official and unofficial standards. Drug dissolution profile assessed at pH 1.2 was studied spectrophotometrically at λ(max) of 245 nm. With the use of various kinetic models, the release mechanism of the drug was analyzed. The parameters, maximum amount of drug release (m(∞)) at time t(∞) were obtained, m(∞) was ≥ 91.36 %, while t(∞) was ≥ 4.5 h. The release rate constant (k) for DG tablets was 15.61 h(sup>-1(/sup>, while, WGO, WGA and SD tablets were 12.90, 11.03 and 10.75 h(-1) respectively. The matrix tablets, which exhibited marked retardation in drug release displayed a Higuchi square root of time model (R(2) > 0.98). The mechanism through which the drug was released was governed by Fickian diffusion release (n values < 0.5). The performance of the drug was affected by the formulation technique in the order of SD > WGO > WGA > DG.

Development of theophylline sustained release dosage form based on Kollidon SR.

PubMed

Reza, Md Selim; Quadir, Mohiuddin Abdul; Haider, Syed Shabbir

2002-01-01

Sustained release theophylline matrix tablets constituting Kollidon SR (Polyvinyl acetate and povidone based matrix retarding polymer) were developed in this study in an attempt to design a dosage form that manifests desirable release profile and thorough adherence to official monographs. Four matrix tablet formulations were prepared by dry blending and direct compression of Kollidon SR and HPMC-15cps (hydroxypropylmethylcellulose) in varying proportion with fixed percentage of theophylline. Tablets containing only Kollidon SR with the active ingredient demonstrated a rapid rate of drug release with an initial burst effect. Incorporation of HPMC-15cps in the matrix tablet prolonged the release of drug with subsequent minimization of burst effect as confirmed by mean dissolution time, T50 and Higuchi release rate data. Among the batches containing HPMC-15 cps, a direct relationship was obtained between release rate and the percentage of HPMC used. A suitable controlled release profile was obtained with the matrix tablets containing 20% Kollidon SR and 30% HPMC-15cps. The formulation showed close resemblance to commercial products and compliance with USP specification. The results were explored and explained by the difference of physico-chemical property and hydration characteristics of the polymers. In addition to this result, the exponential model was applied to characterize the drug release behaviour from polymeric systems. It was found that, Fickian release is predominant in tablets containing Kollidon SR alone and non-Fickian mechanism plays an important role in the release of drug from HPMC containing tablets with a trend towards zero-order or case II release. In vitro release profile of two commercial brands were also undertaken for comparison and modulation of the experimental batches.

Atmospheric Nitrogen Trifluoride: Optimized emission estimates using 2-D and 3-D Chemical Transport Models from 1973-2008

NASA Astrophysics Data System (ADS)

Ivy, D. J.; Rigby, M. L.; Prinn, R. G.; Muhle, J.; Weiss, R. F.

2009-12-01

We present optimized annual global emissions from 1973-2008 of nitrogen trifluoride (NF3), a powerful greenhouse gas which is not currently regulated by the Kyoto Protocol. In the past few decades, NF3 production has dramatically increased due to its usage in the semiconductor industry. Emissions were estimated through the 'pulse-method' discrete Kalman filter using both a simple, flexible 2-D 12-box model used in the Advanced Global Atmospheric Gases Experiment (AGAGE) network and the Model for Ozone and Related Tracers (MOZART v4.5), a full 3-D atmospheric chemistry model. No official audited reports of industrial NF3 emissions are available, and with limited information on production, a priori emissions were estimated using both a bottom-up and top-down approach with two different spatial patterns based on semiconductor perfluorocarbon (PFC) emissions from the Emission Database for Global Atmospheric Research (EDGAR v3.2) and Semiconductor Industry Association sales information. Both spatial patterns used in the models gave consistent results, showing the robustness of the estimated global emissions. Differences between estimates using the 2-D and 3-D models can be attributed to transport rates and resolution differences. Additionally, new NF3 industry production and market information is presented. Emission estimates from both the 2-D and 3-D models suggest that either the assumed industry release rate of NF3 or industry production information is still underestimated.

Decontamination of mass casualties--re-evaluating existing dogma.

PubMed

Levitin, Howard W; Siegelson, Henry J; Dickinson, Stanley; Halpern, Pinchas; Haraguchi, Yoshikura; Nocera, Anthony; Turineck, David

2003-01-01

The events of 11 September 2001 became the catalyst for many to shift their disaster preparedness efforts towards mass-casualty incidents. Emergency responders, healthcare workers, emergency managers, and public health officials worldwide are being tasked to improve their readiness by acquiring equipment, providing training and implementing policy, especially in the area of mass-casualty decontamination. Accomplishing each of these tasks requires good information, which is lacking. Management of the incident scene and the approach to victim care varies throughout the world and is based more on dogma than scientific data. In order to plan effectively for and to manage a chemical, mass-casualty event, we must critically assess the criteria upon which we base our response. This paper reviews current standards surrounding the response to a release of hazardous materials that results in massive numbers of exposed human survivors. In addition, a significant effort is made to prepare an international perspective on this response. Preparations for the 24-hour threat of exposure of a community to hazardous material are a community responsibility for first-responders and the hospital. Preparations for a mass-casualty event related to a terrorist attack are a governmental responsibility. Reshaping response protocols and decontamination needs on the differences between vapor and liquid chemical threats can enable local responders to effectively manage a chemical attack resulting in mass casualties. Ensuring that hospitals have adequate resources and training to mount an effective decontamination response in a rapid manner is essential.

The validity of open-source data when assessing jail suicides.

PubMed

Thomas, Amanda L; Scott, Jacqueline; Mellow, Jeff

2018-05-09

The Bureau of Justice Statistics' Deaths in Custody Reporting Program is the primary source for jail suicide research, though the data is restricted from general dissemination. This study is the first to examine whether jail suicide data obtained from publicly available sources can help inform our understanding of this serious public health problem. Of the 304 suicides that were reported through the DCRP in 2009, roughly 56 percent (N = 170) of those suicides were identified through the open-source search protocol. Each of the sources was assessed based on how much information was collected on the incident and the types of variables available. A descriptive analysis was then conducted on the variables that were present in both data sources. The four variables present in each data source were: (1) demographic characteristics of the victim, (2) the location of occurrence within the facility, (3) the location of occurrence by state, and (4) the size of the facility. Findings demonstrate that the prevalence and correlates of jail suicides are extremely similar in both open-source and official data. However, for almost every variable measured, open-source data captured as much information as official data did, if not more. Further, variables not found in official data were identified in the open-source database, thus allowing researchers to have a more nuanced understanding of the situational characteristics of the event. This research provides support for the argument in favor of including open-source data in jail suicide research as it illustrates how open-source data can be used to provide additional information not originally found in official data. In sum, this research is vital in terms of possible suicide prevention, which may be directly linked to being able to manipulate environmental factors.

Standard Test Procedures for Evaluating Various Leak Detection Methods

EPA Pesticide Factsheets

Learn about protocols that testers could use to demonstrate that an individual release detection equipment type could meet the performance requirements noted in the federal UST requirements for detecting leaks.

[Testing of medicinal products produced from pooled plasma].

PubMed

Unkelbach, U; Hunfeld, A; Breitner-Ruddock, S

2014-10-01

Medicinal products produced from human plasma fall under the administrative batch release procedure of the competent authority. In Germany, this has been carried out since 1995 by the Paul Ehrlich Institute (PEI), the responsible state control agency for blood products. Medicinal products released for the European and national market are tested for quality, efficacy and safety. Experimental testing of the final product and the starting materials, the plasma pools, as well as control of the production documentation guarantee a constantly high product safety. In the 28,000 batches tested since the beginning of the state controlled batch release testing of these blood products at the PEI, there has been no transmission of infectious viruses (HIV, HBV and HCV) to any patient. The batch release has made a contribution to the improvement of product quality. This procedure is still an important tool to ensure safety of blood products. The PEI is integrated in the batch release network of the European Directorate for the Quality of Medicines & Health Care (EDQM) in Strasbourg. Regulations and guidelines for official control authority batch release (OCABR) ensure harmonized procedures for mutual recognition of batch release on the European level. The EU certificates and German national certificates are requested and accepted in over 70 countries worldwide. Experimental testing in the EU and the requisite certificates have developed into a seal of quality for the world market.

Protocols for Home Energy Upgrades

EPA Pesticide Factsheets

Remodeling or renovating an existing home not only has the potential to release pollutants into the home; it is also an opportunity to make changes that will improve the indoor air quality in your home.

Rosetta3: An Object-Oriented Software Suite for the Simulation and Design of Macromolecules

PubMed Central

Leaver-Fay, Andrew; Tyka, Michael; Lewis, Steven M.; Lange, Oliver F.; Thompson, James; Jacak, Ron; Kaufman, Kristian; Renfrew, P. Douglas; Smith, Colin A.; Sheffler, Will; Davis, Ian W.; Cooper, Seth; Treuille, Adrien; Mandell, Daniel J.; Richter, Florian; Ban, Yih-En Andrew; Fleishman, Sarel J.; Corn, Jacob E.; Kim, David E.; Lyskov, Sergey; Berrondo, Monica; Mentzer, Stuart; Popović, Zoran; Havranek, James J.; Karanicolas, John; Das, Rhiju; Meiler, Jens; Kortemme, Tanja; Gray, Jeffrey J.; Kuhlman, Brian; Baker, David; Bradley, Philip

2013-01-01

We have recently completed a full re-architecturing of the Rosetta molecular modeling program, generalizing and expanding its existing functionality. The new architecture enables the rapid prototyping of novel protocols by providing easy to use interfaces to powerful tools for molecular modeling. The source code of this rearchitecturing has been released as Rosetta3 and is freely available for academic use. At the time of its release, it contained 470,000 lines of code. Counting currently unpublished protocols at the time of this writing, the source includes 1,285,000 lines. Its rapid growth is a testament to its ease of use. This document describes the requirements for our new architecture, justifies the design decisions, sketches out central classes, and highlights a few of the common tasks that the new software can perform. PMID:21187238

Sensitivity Analysis and Simulation of Theoretical Response of Ceramics to Strong Magnetic Fields

DTIC Science & Technology

2016-09-01

Weapons and Materials Research Directorate, ARL Approved for public release; distribution is unlimited. FOR OFFICIAL USE ONLY...Compounds. 2013;551:568–577. 4. Terada N, Suzuki HS, Suzuki TS, Kitazawa H, Sakka Y, Kaneko K, Metoki N. In situ neutron diffraction study of...TS, Kitazawa H, Sakka Y, Kaneko K, Metoki N. Neutron diffraction texture analysis for alpha-Al2O3 oriented by a high magnetic field and sintering

Decontamination Workshop for Emergency Responding Personnel How Clean is Clean Enough 12-14 September 2007

DTIC Science & Technology

2008-09-01

refers to a Medical Treatment Facility (MTF), can we assume that disrobing is sufficient? Is it possible to develop specific site clearance criteria ...o First responders , medical personnel, and the HAZMAT team o Incident Commanders o Public information officials o Hospitals and hospital networks ...clean personnel (both victims and first responders ) need to be when they are released from the incident site (or treatment facility for those that make

Non-Magnetic On-Chip Resonant Acousto-Optic Isolator at 780 nm

DTIC Science & Technology

2017-08-04

SPONSOR/MONITOR’S ACRONYM(S) Air Force Research Laboratory Space Vehicles Directorate 3550 Aberdeen Avenue SE Kirtland AFB, NM 87117-5776 AFRL /RVBYE 11...Belvoir, VA 22060-6218 AFRL /RVIL Kirtland AFB, NM 87117-5776 Official Record Copy AFRL /RVBYE/Dr. Brian Kasch 1 cy Approved for public release... AFRL -RV-PS- AFRL -RV-PS- TR-2017-0170 TR-2017-0170 NON-MAGNETIC ON-CHIP RESONANT ACOUSTO- OPTIC ISOLATOR AT 780 nm Gaurav Bahl University of

Electron Attachment to C2 Fluorocarbon Radicals at High Temperature (Postprint)

DTIC Science & Technology

2016-01-28

Vehicles Directorate 3550 Aberdeen Avenue SE Kirtland AFB, NM 87117-5776 8. PERFORMING ORGANIZATION REPORT NUMBER AFRL -RV-PS-TP-2015-0014 9...cy AFRL /RVIL Kirtland AFB, NM 87117-5776 2 cys Official Record Copy AFRL /RVBXT/Dr. Raymond Bemish 1 cy Approved for public release; distribution... AFRL -RV-PS- TP-2015-0014 AFRL -RV-PS- TP-2015-0014 ELECTRON ATTACHMENT TO C2 FLUOROCARBON RADICALS AT HIGH TEMPERATURE (POSTPRINT) Nicholas S

Moment-Preserving Computational Approach for High Energy Charged Particle Transport

DTIC Science & Technology

2016-05-16

Kirtland AFB, NM 87117-5776 AFRL /RVBXR 11. SPONSOR/MONITOR’S REPORT NUMBER(S) AFRL -RV-PS-TR-2016-0102 12. DISTRIBUTION / AVAILABILITY...VA 22060-6218 1 cy AFRL /RVIL Kirtland AFB, NM 87117-5776 2 cys Official Record Copy AFRL /RVBXR/Adrian Wheelock 1 cy Approved for public release; distribution is unlimited. 78 ... AFRL -RV-PS- AFRL -RV-PS- TR-2016-0102 TR-2016-0102 MOMENT-PRESERVING COMPUTATIONAL APPROACH FOR HIGH ENERGY CHARGED PARTICLE TRANSPORT Anil

Impact of Polarizing Non-Lambertian Surface and Volume Scattering on Polarized Light Signatures: Importance to Remote Sensing

DTIC Science & Technology

2016-12-08

RVIL Kirtland AFB, NM 87117-5776 Official Record Copy AFRL /RVBYI/Jeannette van den Bosch 1 cy Approved for public release; distribution is... AFRL -RV-PS- TR-2017-0156 AFRL -RV-PS- TR-2017-0156 IMPACT OF POLARIZING NON-LAMBERTIAN SURFACE AND VOLUME SCATTERING ON POLARIZED LIGHT...3550 Aberdeen Ave SE AIR FORCE MATERIEL COMMAND KIRTLAND AIR FORCE BASE, NM 87117-5776 DTIC COPY NOTICE AND SIGNATURE PAGE Using Government

Remaking of an American Icon: An NPS Graduate School Case Competition

DTIC Science & Technology

2007-06-01

thesis are those of the author and do not reflect the official policy or position of the Department of Defense or the U.S. Government . 12a...rubric. i.e., a three tiered judging process designed to ensure top-quality ideas flowed to corporate executives. In the final stage of the judging...9 August 2006, available from http://www.jdpower.com/ corporate /news/releases/pressrelease.asp?ID=2006133; Internet; accessed 24 April 2007. 25 Ibid

Modernizing Immunization Practice Through the Use of Cloud Based Platforms.

PubMed

Bell, Cameron; Atkinson, Katherine M; Wilson, Kumanan

2017-04-01

Collection of timely and accurate immunization information is essential for effective immunization programs. Current immunization information systems have important limitations that impact the ability to collect this data. Based on our experience releasing a national immunization app we describe a cloud-based platform that would allow individuals to store their records digitally and exchange these records with public health information systems thus improving the quality of immunization information held by individuals and public health officials.

Super p53 for Treatment of Ovarian Cancer

DTIC Science & Technology

2017-09-01

System 3, Clontech) containing wt-p53, p53-CC, and ZsGreen (control) were made. Ad-ZsGreen was tested in ID8 cells, which showed very high expression...views, opinions and/or findings contained in this report are those of the author(s) and should not be construed as an official Department of the Army...MONITOR’S REPORT NUMBER(S) 12. DISTRIBUTION / AVAILABILITY STATEMENT Approved for Public Release; Distribution Unlimited 13. SUPPLEMENTARY NOTES 14

Toward the Use of an Upper Ontology for U.S. Government and U.S. Military Domains: An Evaluation

DTIC Science & Technology

2004-09-01

applications outpace other government applications, but this state of affairs is changing with the advent of eGov [48]. Recently, the Defense Advanced...DOCUMENTNUMBER MTR 04B0000063 MITRE TECHNICAL REPORT Toward the Use of an Upper Ontology for U.S. Government and U.S. Military Domains: An...construed as an official Government position, policy, or decision, unless designated by other documentation. Approved for public release (04-0603

NUCLEAR ESPIONAGE: Report Details Spying on Touring Scientists.

PubMed

Malakoff, D

2000-06-30

A congressional report released this week details dozens of sometimes clumsy attempts by foreign agents to obtain nuclear secrets from U.S. nuclear scientists traveling abroad, ranging from offering scientists prostitutes to prying off the backs of their laptop computers. The report highlights the need to better prepare traveling researchers to safeguard secrets and resist such temptations, say the two lawmakers who requested the report and officials at the Department of Energy, which employs the scientists.

Mixed Methods Approach to Identify Factors and the Extent to Which They Influence Medical/Surgical Prime Vendor Use

DTIC Science & Technology

2014-03-27

2009). Choosing the Right Type of Rotation in PCA and EFA. JALT Testing & Evaluation Newsletter , 13 (3), 20-25. 102 Bryman , A . (2006). Integrating...FORCE INSTITUTE OF TECHNOLOGY Wright-Patterson Air Force Base, Ohio DISTRIBUTION STATEMENT A . APPROVED FOR PUBLIC RELEASE...official policy or position of the United States Air Force, Department of Defense, or the United States government. This material is declared a work of

Livestock impacts for management of reclaimed land at Navajo Mine: The decision-making process

DOE Office of Scientific and Technical Information (OSTI.GOV)

Estrada, O.J.; Grogan, S.; Gadzia, K.L.

1997-12-31

Livestock grazing is the post-mining use for reclaimed land at Navajo Mine, a large surface coal mine on the Navajo Nation in northwest New Mexico. The Navajo Mine Grazing Management Program (GMP) uses holistic management on approximately 2,083 ha of reclaimed land to plan for final liability release and return of the land to the Navajo Nation, and to minimize the potential for post-release liability. The GMP began in 1991 to establish that livestock grazing on the reclaimed land is sustainable. Assuming that sustainability requires alternatives to conventional land management practices, the GMP created a Management Team consisting of companymore » staff, local, Navajo Nation, and Federal government officials, and technical advisors. Community members contributed to the formation of a holistic goal for the GMP that articulates their values and their desire for sustainable grazing. Major decisions (e.g., artificial insemination, water supply, supplemental feed) are tested against the goal. Biological changes in the land and the grazing animals are monitored daily to provide early feedback to managers, and annually to document the results of grazing. To date, the land has shown resilience to grazing and the animals have generally prospered. Community participation in the GMP and public statements of support by local officials indicate that the GMP`s strategy is likely to succeed.« less

Biophysical characterization of hydrogel-core, lipid-shell nanoparticles (nanolipogels) for HIV chemoprophylaxis

NASA Astrophysics Data System (ADS)

Mahadevan, Reena

Nanoparticles are emerging as versatile vehicles for drug delivery, providing targeting, protection, and controlled-release capabilities to encapsulated cargo. Polymeric nanoparticles made from poly(lactide-co-glycolide) (PLGA) are biodegradable, exhibit tunable drug release, and have encapsulated a wide variety of biological agents. However, PLGA nanoparticles are relatively inefficient at encapsulating small-molecule hydrophilic drugs. Liposomes encapsulate greater amounts of hydrophilic agents and demonstrate good cellular affinity; however, they lack controlled-release functionality. Hydrogel-core lipid-shell nanoparticles, or nanolipogels, combine the controlled-release capability of polymeric nanocarriers with the hydrophilic and cellular affinity of liposomes into a single drug delivery vehicle. This study establishes a facile, reproducible synthetic protocol for nanolipogels and evaluates hydrogel swelling as a mechanism for release of the small hydrophilic antiretroviral azidothymidine from nanolipogels.

Enabling Next-Generation Multicore Platforms in Embedded Applications

DTIC Science & Technology

2014-04-01

mapping to sets 129 − 256 ) to the second page in memory, color 2 (sets 257 − 384) to the third page, and so on. Then, after the 32nd page, all 212 sets...the Real-Time Nested Locking Protocol (RNLP) [56], a recently developed multiprocessor real-time locking protocol that optimally supports the...RELEASE; DISTRIBUTION UNLIMITED 15 In general, the problems of optimally assigning tasks to processors and colors to tasks are both NP-hard in the

Investigation of Particle Accumulation, Chemosensitivity and Thermosensitivity for Effective Solid Tumor Therapy Using Thermosensitive Liposomes and Hyperthermia.

PubMed

Lokerse, Wouter J M; Bolkestein, Michiel; Ten Hagen, Timo L M; de Jong, Marion; Eggermont, Alexander M M; Grüll, Holger; Koning, Gerben A

2016-01-01

Doxorubicin (Dox) loaded thermosensitive liposomes (TSLs) have shown promising results for hyperthermia-induced local drug delivery to solid tumors. Typically, the tumor is heated to hyperthermic temperatures (41-42 °C), which induced intravascular drug release from TSLs within the tumor tissue leading to high local drug concentrations (1-step delivery protocol). Next to providing a trigger for drug release, hyperthermia (HT) has been shown to be cytotoxic to tumor tissue, to enhance chemosensitivity and to increase particle extravasation from the vasculature into the tumor interstitial space. The latter can be exploited for a 2-step delivery protocol, where HT is applied prior to i.v. TSL injection to enhance tumor uptake, and after 4 hours waiting time for a second time to induce drug release. In this study, we compare the 1- and 2-step delivery protocols and investigate which factors are of importance for a therapeutic response. In murine B16 melanoma and BFS-1 sarcoma cell lines, HT induced an enhanced Dox uptake in 2D and 3D models, resulting in enhanced chemosensitivity. In vivo, therapeutic efficacy studies were performed for both tumor models, showing a therapeutic response for only the 1-step delivery protocol. SPECT/CT imaging allowed quantification of the liposomal accumulation in both tumor models at physiological temperatures and after a HT treatment. A simple two compartment model was used to derive respective rates for liposomal uptake, washout and retention, showing that the B16 model has a twofold higher liposomal uptake compared to the BFS-1 tumor. HT increases uptake and retention of liposomes in both tumors models by the same factor of 1.66 maintaining the absolute differences between the two models. Histology showed that HT induced apoptosis, blood vessel integrity and interstitial structures are important factors for TSL accumulation in the investigated tumor types. However, modeling data indicated that the intraliposomal Dox fraction did not reach therapeutic relevant concentrations in the tumor tissue in a 2-step delivery protocol due to the leaking of the drug from its liposomal carrier providing an explanation for the observed lack of efficacy.

New secure communication-layer standard for medical image management (ISCL)

NASA Astrophysics Data System (ADS)

Kita, Kouichi; Nohara, Takashi; Hosoba, Minoru; Yachida, Masuyoshi; Yamaguchi, Masahiro; Ohyama, Nagaaki

1999-07-01

This paper introduces a summary of the standard draft of ISCL 1.00 which will be published by MEDIS-DC officially. ISCL is abbreviation of Integrated Secure Communication Layer Protocols for Secure Medical Image Management Systems. ISCL is a security layer which manages security function between presentation layer and TCP/IP layer. ISCL mechanism depends on basic function of a smart IC card and symmetric secret key mechanism. A symmetry key for each session is made by internal authentication function of a smart IC card with a random number. ISCL has three functions which assure authentication, confidently and integrity. Entity authentication process is done through 3 path 4 way method using functions of internal authentication and external authentication of a smart iC card. Confidentially algorithm and MAC algorithm for integrity are able to be selected. ISCL protocols are communicating through Message Block which consists of Message Header and Message Data. ISCL protocols are evaluating by applying to regional collaboration system for image diagnosis, and On-line Secure Electronic Storage system for medical images. These projects are supported by Medical Information System Development Center. These project shows ISCL is useful to keep security.

Optimization of a sample processing protocol for recovery of Bacillus anthracis spores from soil

USGS Publications Warehouse

Silvestri, Erin E.; Feldhake, David; Griffin, Dale; Lisle, John T.; Nichols, Tonya L.; Shah, Sanjiv; Pemberton, A; Schaefer III, Frank W

2016-01-01

Following a release of Bacillus anthracis spores into the environment, there is a potential for lasting environmental contamination in soils. There is a need for detection protocols for B. anthracis in environmental matrices. However, identification of B. anthracis within a soil is a difficult task. Processing soil samples helps to remove debris, chemical components, and biological impurities that can interfere with microbiological detection. This study aimed to optimize a previously used indirect processing protocol, which included a series of washing and centrifugation steps. Optimization of the protocol included: identifying an ideal extraction diluent, variation in the number of wash steps, variation in the initial centrifugation speed, sonication and shaking mechanisms. The optimized protocol was demonstrated at two laboratories in order to evaluate the recovery of spores from loamy and sandy soils. The new protocol demonstrated an improved limit of detection for loamy and sandy soils over the non-optimized protocol with an approximate matrix limit of detection at 14 spores/g of soil. There were no significant differences overall between the two laboratories for either soil type, suggesting that the processing protocol will be robust enough to use at multiple laboratories while achieving comparable recoveries.

Search for Muon Neutrino Disappearance in the Booster Neutrino Beam of Fermilab; Busqueda de Desaparicion de Neutrinos del Muon en el Haz de Neutrinos del Booster de Fermilab (in Spanish)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mendez Mendez, Diana Patricia

In this work we carried out the disappearance analysis of muon neutrinos produced in the Fermilab Booster Neutrino Beam, using the data released to the public by the collaborations of the MiniBooNE and SciBooNE experiments. The calculations were made with programs in C and C++, implementing the ROOT libraries. From the analysis, using both the classical Pearson method and the Feldman and Cousins frequentist corrections, we obtained the 90\\% C.L. limit for the oscillation parameters sin 22θ and Δm 2 in the region 0.1 ≤ Δm 2 ≤ 10 eV 2 using a two neutrino model. The result presented inmore » this work is consistent with the official one, with small deviations ascribed to round-off errors in the format of the used data, as well as statistical fluctuations in the generation of fake experiments used in the Feldman and Cousins method. As the official one, our result is consistent with the null oscillation hypothesis. This work was carried out independently to the MiniBooNE and SciBooNE collaborations and its results are not official.« less

Detection of the urban release of a bacillus anthracis simulant by air sampling.

PubMed

Garza, Alexander G; Van Cuyk, Sheila M; Brown, Michael J; Omberg, Kristin M

2014-01-01

In 2005 and 2009, the Pentagon Force Protection Agency (PFPA) staged deliberate releases of a commercially available organic pesticide containing Bacillus amyloliquefaciens to evaluate PFPA's biothreat response protocols. In concert with, but independent of, these releases, the Department of Homeland Security sponsored experiments to evaluate the efficacy of commonly employed air and surface sampling techniques for detection of an aerosolized biological agent. High-volume air samplers were placed in the expected downwind plume, and samples were collected before, during, and after the releases. Environmental surface and personal air samples were collected in the vicinity of the high-volume air samplers hours after the plume had dispersed. The results indicate it is feasible to detect the release of a biological agent in an urban area both during and after the release of a biological agent using high-volume air and environmental sampling techniques.

Ovarian dynamics in response to two modified intravaginal progesterone releasing device and oestradiol benzoate based ovulation synchronisation protocols designed for use in Brahman heifers.

PubMed

Edwards, S A A; Atkinson, P C; Satake, N; Boe-Hansen, G; McGowan, M R

2014-07-01

The objective was to investigate the ovarian response of Brahman heifers to two modified ovulation synchronisation protocols developed to increase the proportion of normal synchronous ovulations. Experiment 1 characterised the growth of the ovulatory follicle in heifers (n=19) treated with an intravaginal progesterone releasing device (IPRD) and oestradiol benzoate (ODB), to determine the optimal time to induce ovulation. Using the findings from Experiment 1, Experiment 2 investigated the effect of reducing the duration of IPRD insertion and increasing the interval from IPRD removal to ODB treatment (modified protocol 1 - OPO-6; n=20), and omitting ODB treatment at the time of IPRD insertion (modified protocol 2 - PO-6; n=20). An IPRD (0.78 g progesterone) was inserted at Day 0 (OPO-8) or Day 2 (OPO-6 and PO-6) and all heifers also received 1 mg ODB i.m. Day 8: IPRD removed + 500 μg cloprostenol i.m. At 24 h (OPO-8) and 36 h (OPO-6 and PO-6) post IPRD removal: 1 mg ODB i.m. Fixed-time AI (FTAI) occurred at 54 h for OPO-8 and 72 h for OPO-6 and PO-6, post IPRD removal. After IPRD treatment all OPO-6 and OPO-8 heifers initiated a new follicular wave whereas 25% of PO-6 heifers failed. Diameter of the dominant follicle was larger at FTAI in the PO-6 (11.34 ± 0.50 mm) compared to the OPO-8 protocol (9.74 ± 0.51 mm; P<0.05), but similar to the OPO-6 protocol (10.52 ± 0.51 mm). Proportion of ovulations occurring 12 h prior and 24 h post FTAI was similar for the PO-6 (80%) and OPO-6 (75%) protocols but numerically lower in the OPO-8 heifers (60%). The apparent improvement in ovarian response in heifers treated with the modified protocols needs to be confirmed in larger field studies. Copyright © 2014 Elsevier B.V. All rights reserved.

Understanding Internal Accountability in Nigeria's Routine Immunization System: Perspectives From Government Officials at the National, State, and Local Levels.

PubMed

Erchick, Daniel J; George, Asha S; Umeh, Chukwunonso; Wonodi, Chizoba

2016-12-10

Routine immunization coverage in Nigeria has remained low, and studies have identified a lack of accountability as a barrier to high performance in the immunization system. Accountability lies at the heart of various health systems strengthening efforts recently launched in Nigeria, including those related to immunization. Our aim was to understand the views of health officials on the accountability challenges hindering immunization service delivery at various levels of government. A semi-structured questionnaire was used to interview immunization and primary healthcare (PHC) officials from national, state, local, and health facility levels in Niger State in north central Nigeria. Individuals were selected to represent a range of roles and responsibilities in the immunization system. The questionnaire explored concepts related to internal accountability using a framework that organizes accountability into three axes based upon how they drive change in the health system. Respondents highlighted accountability challenges across multiple components of the immunization system, including vaccine availability, financing, logistics, human resources, and data management. A major focus was the lack of clear roles and responsibilities both within institutions and between levels of government. Delays in funding, especially at lower levels of government, disrupted service delivery. Supervision occurred less frequently than necessary, and the limited decision space of managers prevented problems from being resolved. Motivation was affected by the inability of officials to fulfill their responsibilities. Officials posited numerous suggestions to improve accountability, including clarifying roles and responsibilities, ensuring timely release of funding, and formalizing processes for supervision, problem solving, and data reporting. Weak accountability presents a significant barrier to performance of the routine immunization system and high immunization coverage in Nigeria. As one stakeholder in ensuring the performance of health systems, routine immunization officials reveal critical areas that need to be prioritized if emerging interventions to improve accountability in routine immunization are to have an effect. © 2017 The Author(s); Published by Kerman University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Economical impact associated with a biological therapy prioritization protocol in patients with rheumatoid arthritis in the Hospital of Sagunto.

PubMed

Borrás-Blasco, Joaquín; Casterá, M Dolores-Elvira; Cortes, Xavier; Rosique-Robles, J Dolores; Abad, F Javier

2014-11-01

Until 2010 the cost of biological treatments in Rheumatoid Arthritis (RA) was increasing annually by 15% in our hospital. In 1st January 2011, a Hospital Commission of Biological Therapies involving rheumatology and pharmacy services was created to improve the management of biological drugs and a biological therapy prioritization protocol in RA patients was also established to improve the efficient usage of biological drugs in RA. To evaluate the economic impact associated with a biological therapy prioritization protocol for RA patients in the Hospital of Sagunto. Observational, ambispective study comparing the associated cost of RA patients treated with biological drugs in the pre-protocol (2009 - 2010) versus post-protocol periods (2011 - 2012). RA patients treated with Abatacept (ABA), Adalimumab (ADA), Etanercept (ETN) or Infliximab (IFX) for at least 6 months during the study period (2009 - 2012) were included. In 2012, Tocilizumab (TCZ) was also included in the prioritization protocol. Prioritization protocol was established based on both clinical and economical aspects and supervised case by case by our Commission. Cost savings and economic impact were calculated using Spanish official prices. In the pre-protocol period (2009 - 2010), total expenses were increasing by €110,000, up to €1,761,000 in 2010 (€11,362 pat/year). After protocol implementation, total expenses decreased by 53,676€ on the 2010 - 2011 period, and 149,200€ on the 2011 - 2012 period. On the 2010 - 2011 period the cost of biological therapy per patient-year decreased 355€ (11,007€ pat/year) and additional 653€ (up to 10,354€ pat/year) by 2012, with a cumulative effect of the protocol implementation of 1,008€ per patient-year. In the pre-protocol period (2009), the annual cost/patient was 10.812€ with ETN, 10.942€ with IFX, 12.961€ with ADA and 12.739€ with ABA. By 1st January 2013, the annual cost per patient was 9,469€ with ETN, 10,579€ with IFX, 11,117€ with ADA, 13,540€ with ABA and 14,932€ with TCZ. The creation of our Commission of Biological Therapies is key to rational management of RA patients and optimization of resources, allowing us to save 200,000€ after 2-year efficiency protocol implementation.

Initial verification and validation of RAZORBACK - A research reactor transient analysis code

DOE Office of Scientific and Technical Information (OSTI.GOV)

Talley, Darren G.

2015-09-01

This report describes the work and results of the initial verification and validation (V&V) of the beta release of the Razorback code. Razorback is a computer code designed to simulate the operation of a research reactor (such as the Annular Core Research Reactor (ACRR)) by a coupled numerical solution of the point reactor kinetics equations, the energy conservation equation for fuel element heat transfer, and the mass, momentum, and energy conservation equations for the water cooling of the fuel elements. This initial V&V effort was intended to confirm that the code work to-date shows good agreement between simulation and actualmore » ACRR operations, indicating that the subsequent V&V effort for the official release of the code will be successful.« less

Experimental Study of Electronic Quantum Interference, Photonic Crystal Cavity, Photonic Band Edge Effects for Optical Amplification

DTIC Science & Technology

2016-01-26

MONITOR’S REPORT Kirtland AFB, NM 87117-5776 NUMBER(S) AFRL -RV-PS-TR-2016-0003 12. DISTRIBUTION / AVAILABILITY STATEMENT Approved for public release...22060-6218 1 cy AFRL /RVIL Kirtland AFB, NM 87117-5776 2 cys Official Record Copy AFRL /RVSS/David Cardimona 1 cy 12 Approved for... AFRL -RV-PS- AFRL -RV-PS- TR-2016-0003 TR-2016-0003 EXPERIMENTAL STUDY OF ELECTRONIC QUANTUM INTERFERENCE, PHOTONIC CRYSTAL CAVITY, PHOTONIC BAND

Consistent Continuum Particle Modeling of Hypersonic Flows and Development of HybridSimulation Capability

DTIC Science & Technology

2017-07-01

Directorate 3550 Aberdeen Avenue SE Kirtland AFB, NM 87117-5776 AFRL /RVBYE 11. SPONSOR/MONITOR’S REPORT NUMBER(S) AFRL -RV-PS-TR-2017-0152 12. DISTRIBUTION...Belvoir, VA 22060-6218 AFRL /RVIL Kirtland AFB, NM 87117-5776 Official Record Copy AFRL /RVBYE/Dr. Raymond Bemish 1 cy Approved for public release... AFRL -RV-PS- TR-2017-0152 AFRL -RV-PS- TR-2017-0152 CONSISTENT CONTINUUM-PARTICLE MODELING OF HYPERSONIC FLOWS AND DEVELOPMENT OF HYBRID

Atomistic- and Meso-Scale Computational Simulations for Developing Multi-Timescale Theory for Radiation Degradation in Electronic and Optoelectronic Devices

DTIC Science & Technology

2017-02-13

3550 Aberdeen Ave., SE 11. SPONSOR/MONITOR’S REPORT Kirtland AFB, NM 87117-5776 NUMBER(S) AFRL -RV-PS-TR-2016-0161 12. DISTRIBUTION / AVAILABILITY...RVIL Kirtland AFB, NM 87117-5776 2 cys Official Record Copy AFRL /RVSW/David Cardimona 1 cy 22 Approved for public release; distribution is unlimited. ... AFRL -RV-PS- AFRL -RV-PS- TR-2016-0161 TR-2016-0161 ATOMISTIC- AND MESO-SCALE COMPUTATIONAL SIMULATIONS FOR DEVELOPING MULTI-TIMESCALE THEORY FOR

Child Labor Violations and Sweatshops in the U.S.

DTIC Science & Technology

1990-03-16

I U~skd Sta Gaa -c o (WS GAD Testimony " AD-A280 774 0 For Release Child Labor Violations and on Delivery Sweatshops in the U.S. Expected at 9:30 am...standards. In addition, there appears to be a widespread problem of " sweatshops "--workplaces that regularly violate both wage or child labor laws and...Consistent With the Widespread Existence of Sweatshops . Federal and state enforcement officials believe " sweatshops " exist throughout the nation, especially

Mechanisms of Drug Resistance in Plasmodium Falciparum

DTIC Science & Technology

1994-06-14

for public release; distribution unlimited The views, opinions and/or findings contained in this report are those of the author( s ) and should not be...construed as an official Department of the Army position, policy or decision unless so designated by other documentation. DTIC QUALITY 110MNDM S 94-20472...tnforWotio,. Sand CO Q~meflt = th dn estimate or any other aseof ftm C@Igd0AOf ,nfO•itm. nge.fdff t-. tor rduciXng ths 0d 10 tovasthmngton Hea•l•are• s Se

nCTEQ15 - Global analysis of nuclear parton distributions with uncertainties

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kusina, A.; Kovarik, Karol; Jezo, T.

2015-09-01

We present the first official release of the nCTEQ nuclear parton distribution functions with errors. The main addition to the previous nCTEQ PDFs is the introduction of PDF uncertainties based on the Hessian method. Another important addition is the inclusion of pion production data from RHIC that give us a handle on constraining the gluon PDF. This contribution summarizes our results from arXiv:1509.00792 and concentrates on the comparison with other groups providing nuclear parton distributions.

nCTEQ15 - Global analysis of nuclear parton distributions with uncertainties

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kusina, A.; Kovarik, K.; Jezo, T.

2015-09-04

We present the first official release of the nCTEQ nuclear parton distribution functions with errors. The main addition to the previous nCTEQ PDFs is the introduction of PDF uncertainties based on the Hessian method. Another important addition is the inclusion of pion production data from RHIC that give us a handle on constraining the gluon PDF. This contribution summarizes our results from arXiv:1509.00792, and concentrates on the comparison with other groups providing nuclear parton distributions.

The Apollo spacecraft: A chronology volume 4, 21 January 1966 - 13 July 1974

NASA Technical Reports Server (NTRS)

Ertel, I. D.; Newkirk, R. W.; Brooks, C. G.

1978-01-01

This final volume of the chronology is divided into three parts: (1) preparation for flight, the accident, and investigation; (2) recovery, spacecraft redefinition, and the first manned flight; and (3) man circles the moon, the Eagle lands, and manned space exploration. Congressional documents, official correspondence, government and contractor reports, memoranda, working papers, and minutes of meetings were used as primary sources. A relatively few entries are based on press releases and newspaper and magazine articles.

WIAMan Technology Demonstrator Sensor Codes Conforming to International Organization for Standardization/Technical Standard (ISO/TS) 13499

DTIC Science & Technology

2016-03-01

in this report are not to be construed as an official Department of the Army position unless so designated by other authorized documents. Citation of...gravity, or pretest . 1 Approved for public release; distribution is unlimited. Fine Location 2 Code position 9–10: This substring represents the spacial...itself. For example, upper, pretest , or Hybrid III mid-sized male ATD. Physical dimension Code position 13–14: This substring represents the type of the

Regulation of BRCA1 Function by DNA Damage-Induced Site-Specific Phosphorylation

DTIC Science & Technology

2005-06-01

Nature 382, 678-679. 8. Haile , D.T., and Parvin, J.D. (1999). Activation of transcription in vitro by the BRCAI Carboxyl-terminal domain. J. Biol. Chem...for Public Release; Distribution Unlimited The views, opinions and/or findings contained in this report are those of the author(s) and should not be...construed as an official Department of the Army position, policy or decision unless so designated by other documentation. 20051101 125 REPOR DCI P Form

Dynamics and Control of Mechanical Energy Propagation in Granular Systems

DTIC Science & Technology

2012-01-01

recover the linear approximation made by Job et. al. [2] for this collision. [1] S . Plimpton , J. Comput. Phys, 117, 1 (1995). [2] S . Job, F. Santibanez, F. Tapia, F. Melo, Ultrasonics 48, 506 (2008). ...the author( s ) and should not contrued as an official Department of the Army position, policy or decision, unless so designated by other documentation...12. DISTRIBUTION AVAILIBILITY STATEMENT Approved for Public Release; Distribution Unlimited UU 9. SPONSORING/MONITORING AGENCY NAME( S ) AND ADDRESS

Jens Esmark's Christiania (Oslo) meteorological observations 1816-1838: the first long-term continuous temperature record from the Norwegian capital homogenized and analysed

NASA Astrophysics Data System (ADS)

Hestmark, Geir; Nordli, Øyvind

2016-11-01

In 2010 we rediscovered the complete set of meteorological observation protocols made by Jens Esmark (1762-1839) during his years of residence in the Norwegian capital of Oslo (then Christiania). From 1 January 1816 to 25 January 1839, Esmark at his house in Øvre Voldgate in the morning, early afternoon and late evening recorded air temperature with state-of-the-art thermometers. He also noted air pressure, cloud cover, precipitation and wind directions, and experimented with rain gauges and hygrometers. From 1818 to the end of 1838 he twice a month provided weather tables to the official newspaper Den Norske Rigstidende, and thus acquired a semi-official status as the first Norwegian state meteorologist. This paper evaluates the quality of Esmark's temperature observations and presents new metadata, new homogenization and analysis of monthly means. Three significant shifts in the measurement series were detected, and suitable corrections are proposed. The air temperature in Oslo during this period is shown to exhibit a slow rise from 1816 towards 1825, followed by a slighter fall again towards 1838.

J-Plus Web Portal

NASA Astrophysics Data System (ADS)

Civera Lorenzo, Tamara

2017-10-01

Brief presentation about the J-PLUS EDR data access web portal (http://archive.cefca.es/catalogues/jplus-edr) where the different services available to retrieve images and catalogues data have been presented.J-PLUS Early Data Release (EDR) archive includes two types of data: images and dual and single catalogue data which include parameters measured from images. J-PLUS web portal offers catalogue data and images through several different online data access tools or services each suited to a particular need. The different services offered are: Coverage map Sky navigator Object visualization Image search Cone search Object list search Virtual observatory services: Simple Cone Search Simple Image Access Protocol Simple Spectral Access Protocol Table Access Protocol

Assessing the In Vitro Drug Release from Lipid-Core Nanocapsules: a New Strategy Combining Dialysis Sac and a Continuous-Flow System.

PubMed

de Andrade, Diego Fontana; Zuglianello, Carine; Pohlmann, Adriana Raffin; Guterres, Silvia Stanisçuaski; Beck, Ruy Carlos Ruver

2015-12-01

The in vitro assessment of drug release from polymeric nanocapsules suspensions is one of the most studied parameters in the development of drug-loaded nanoparticles. Nevertheless, official methods for the evaluation of drug release from submicrometric carriers are not available. In this work, a new approach to assess the in vitro drug release profile from drug-loaded lipid-core nanocapsules (LNC) was proposed. A continuous-flow system (open system) was designed to evaluate the in vitro drug release profiles from different LNC formulations containing prednisolone or clobetasol propionate (LNC-CP) as drug model (LNC-PD) using a homemade apparatus. The release medium was constantly renewed throughout the experiment. A dialysis bag containing 5 mL of formulation (0.5 mg mL(-1)) was maintained inside the apparatus, under magnetic stirring and controlled temperature (37°C). In parallel, studies based on the conventional dialysis sac technique (closed system) were performed. It was possible to discriminate the in vitro drug release profile of different formulations using the open system. The proposed strategy improved the sink condition, by constantly renewing the release medium, thus maintaining the drug concentration farther from the saturated concentration in the release medium. Moreover, problems due to sampling errors can be easily overcome using this semi-automated system, since the collection is done automatically without interference from the analyst. The system proposed in this paper brings important methodological and analytical advantages, becoming a promising prototype semi-automated apparatus for performing in vitro drug release studies from drug-loaded lipid-core nanocapsules and other related nanoparticle drug delivery systems.

Use of GDNF Releasing Nanofiber Nerve Guide Conduits for the Repair of Conus Medullaris/Cauda Equina Injury in the Nonhuman Primate

DTIC Science & Technology

2015-02-01

repair of conus medullaris/cauda equina injury in rhesus macaques using a biodegradable bridging graft that releasing the trophic factor, GDNF. All...and biodegradable nerve guidance channels as bridging grafts. The follow section describes the methods and protocols for laminectomy, ventral root...in saline until being grafted, 8. For use of a bridging biodegradable NGC segment, the NGCs were fabricated and comprised of electrospun

Report of Apollo 204 Review Board to the Administrator, National Aeronautics and Space Administration . Appendix F ; Schedule of Physical Evidence

NASA Technical Reports Server (NTRS)

1967-01-01

Immediately following the Apollo 204 accident of January 27, 1961. all associated equipment and material were impounded. Release of this equipment and material for normal use was under the close control of the Apollo 204 Review Board. Apollo Review Board Administrative Procedure No. 11, February 11, 1961, established the Apollo 204 Review Board Material Release Record (MRR). This MRR was the official form used to release material from full impoundment and was valid only after being approved by the Board and signed by a Member. The form was used as the authority to place any impounded item into one of the three Categories defined in Administrative Procedure No. 11. This appendix contains all of the authorized MRR's. Each item submitted on an MRR was given a control number; a description, including the part number and serial number; the relevance and location to the accident; any constraints before release; and the control category. The categories placed on the equipment were as follows: Category A - Items which may have a significant influence or bearing on the results or findings of the Apollo 204 Review Board; Category B - All material other than Category A which is considered relevant to the Apollo 204 Review Board investigation; Category C - Material released from Board jurisdiction. Several classes of equipment were released by special Board action prior to the establishment of the MRR system. The operating procedure for release of these classes is Enclosure F-l to this appendix.

How do nurses, midwives and health visitors contribute to protocol-based care? A synthesis of the UK literature.

PubMed

Ilott, Irene; Booth, Andrew; Rick, Jo; Patterson, Malcolm

2010-06-01

To explore how nurses, midwives and health visitors contribute to the development, implementation and audit of protocol-based care. Protocol-based care refers to the use of documents that set standards for clinical care processes with the intent of reducing unacceptable variations in practice. Documents such as protocols, clinical guidelines and care pathways underpin evidence-based practice throughout the world. An interpretative review using the five-stage systematic literature review process. The data sources were the British Nursing Index, CINAHL, EMBASE, MEDLINE and Web of Science from onset to 2005. The Journal of Integrated Care Pathways was hand searched (1997-June 2006). Thirty three studies about protocol-based care in the United Kingdom were appraised using the Qualitative Assessment and Review Instrument (QARI version 2). The literature was synthesized inductively and deductively, using an official 12-step guide for development as a framework for the deductive synthesis. Most papers were descriptive, offering practitioner knowledge and positive findings about a locally developed and owned protocol-based care. The majority were instigated in response to clinical need or service re-design. Development of protocol-based care was a non-linear, idiosyncratic process, with steps omitted, repeated or completed in a different order. The context and the multiple purposes of protocol-based care influenced the development process. Implementation and sustainability were rarely mentioned, or theorised as a change. The roles and activities of nurses were so understated as to be almost invisible. There were notable gaps in the literature about the resource use costs, the engagement of patients in the decision-making process, leadership and the impact of formalisation and new roles on inter-professional relations. Documents that standardise clinical care are part of the history of nursing as well as contemporary evidence-based care and expanded roles. Considering the proliferation and contested nature of protocol-based care, the dearth of literature about the contribution, experience and outcomes for nurses, midwives and health visitors is noteworthy and requires further investigation. (c) 2010 Elsevier Ltd. All rights reserved.

Astressin B, a corticotropin-releasing hormone receptor antagonist, accelerates the return to normal luteal function after an inflammatory-like stress challenge in the rhesus monkey.

PubMed

Xiao, Ennian; Xia-Zhang, Linna; Vulliemoz, Nicolas; Rivier, Jean; Ferin, Michel

2007-02-01

Endogenous release of CRH in stress has been associated with a dysfunctional reproductive endocrine axis. In the rhesus monkey, an inflammatory-like stress challenge in the luteal phase decreases luteal secretory function. Here, we tested the effectiveness of astressin B, a nonspecific CRH receptor antagonist, in constraining the deleterious impact of a 10-d lipopolysaccharide (LPS) challenge on the menstrual cycle. Two protocols were carried out in nine animals. In the first, the animals, after showing two normal consecutive control cycles, were injected daily for 10 days with LPS (75-125 mug/d) during the luteal phase of the cycle. The animals were followed through the two postchallenge cycles. The second protocol, carried out in the following year, was identical with protocol 1, except that the animals were treated with astressin B (0.45 mg/kg) 1 h before each daily LPS challenge during the luteal phase. Blood samples were obtained daily to document cyclic hormones levels. The LPS challenge significantly decreased luteal progesterone and LH release during the challenge cycle. Inhibition of luteal progesterone extended to the two successive postchallenge cycles. Astressin B treatment prevented luteal LH but not luteal progesterone decrease during the treatment cycle and restored normal progesterone secretion during the two posttreatment cycles. We conclude that the deleterious impact of a short-term inflammatory stress challenge on luteal function is far longer than the stress period itself. Systemic administration of astressin B accelerates the return to normal luteal function, presumably by restoring normal neuroendocrine regulation of gonadotropin secretion.

PLGA microspheres encapsulating siRNA.

PubMed

De Rosa, Giuseppe; Salzano, Giuseppina

2015-01-01

The therapeutic use of small interfering RNA (siRNA) represents a new and powerful approach to suppress the expression of pathologically genes. However, biopharmaceutical drawbacks, such as short half-life, poor cellular uptake, and unspecific distribution into the body, hamper the development of siRNA-based therapeutics. Poly(lactide-co-glycolide), (PLGA) microspheres can be a useful tool to overcome these issues. siRNA can be encapsulated into the PLGA microspheres, which protects the loaded nucleic acid against the enzymatic degradation. Moreover, PLGA microspheres can be injected directly into the action site, where the siRNA can be released in controlled manner, thus avoiding the need of frequent invasive administrations. The complete biodegradability of PLGA to monomers easily metabolized by the body, and its approval by FDA and EMA for parenteral administration, assure the safety of this copolymer and do not require the removal of the device after the complete drug release. In chapter, a basic protocol for the preparation of PLGA microspheres encapsulating siRNA is described. This protocol is based on a double emulsion/solvent evaporation technique, a well known and easy to reproduce method. This specific protocol has been developed to encapsulate a siRNA anti-TNFα in PLGA microspheres, and it has been designed and optimized to achieve high siRNA encapsulation efficiency and slow siRNA release in vitro. However, it can be extended also to other siRNA as well as other RNA or DNA-based oligonucleotides (miRNA, antisense, decoy, etc.). Depending on the applications, chemical modifications of the backbone and site-specific modification within the siRNA sequences could be required.

Effects of myofascial release after high-intensity exercise: a randomized clinical trial.

PubMed

Arroyo-Morales, Manuel; Olea, Nicolas; Martinez, Manuel; Moreno-Lorenzo, Carmen; Díaz-Rodríguez, Lourdes; Hidalgo-Lozano, Amparo

2008-03-01

The usefulness of massage as a recovery method after high-intensity exercise has yet to be established. We aimed to investigate the effects of whole-body massage on heart rate variability (HRV) and blood pressure (BP) after repeated high-intensity cycling exercise under controlled and standardized pretest conditions. The study included 62 healthy active individuals. After baseline measurements, the subjects performed standardized warm-up exercises followed by three 30-second Wingate tests. After completing the exercise protocol, the subjects were randomly assigned to a massage (myofascial release) or placebo (sham treatment with disconnected ultrasound and magnetotherapy equipment) group for a 40-minute recovery period. Holter recording and BP measurements were taken after exercise protocol and after the intervention. After the exercise protocol, both groups showed a significant decrease in normal-to-normal interval, HRV index, diastolic BP (P > .001), and low-frequency domain values (P = .006). After the recovery period, HRV index (P = .42) and high-frequency (HF) (P = .94) values were similar to baseline levels in the massage group, whereas the HRV index tended (P = .05) to be lower and the HF was significantly (P < .01) lower vs baseline values in the placebo group, which also showed a tendency (P = .06) for HF to be lower than after the exercise. Likewise, diastolic BP returned to baseline levels in the massage group (P = .45) but remained lower in the placebo group (P = .02). Myofascial release massage favors the recovery of HRV and diastolic BP after high-intensity exercise (3 Wingate tests) to preexercise levels.

Prehospital care training in a rapidly developing economy: a multi-institutional study.

PubMed

Vyas, Dinesh; Hollis, Michael; Abraham, Rohit; Rustagi, Neeti; Chandra, Siddharth; Malhotra, Ajai; Rajpurohit, Vikas; Purohit, Harshada; Pal, Ranabir

2016-06-01

The trauma pandemic is one of the leading causes of death worldwide but especially in rapidly developing economies. Perhaps, a common cause of trauma-related mortality in these settings comes from the rapid expansion of motor vehicle ownership without the corresponding expansion of national prehospital training in developed countries. The resulting road traffic injuries often never make it to the hospital in time for effective treatment, resulting in preventable disability and death. The current article examines the development of a medical first responder training program that has the potential to reduce this unnecessary morbidity and mortality. An intensive training workshop has been differentiated into two progressive tiers: acute trauma training (ATT) and broad trauma training (BTT) protocols. These four-hour and two-day protocols, respectively, allow for the mass education of laypersons-such as police officials, fire brigade, and taxi and/or ambulance drivers-who are most likely to interact first with prehospital victims. Over 750 ATT participants and 168 BTT participants were trained across three Indian educational institutions at Jodhpur and Jaipur. Trainees were given didactic and hands-on education in a series of critical trauma topics, in addition to pretraining and post-training self-assessments to rate clinical confidence across curricular topics. Two-sample t-test statistical analyses were performed to compare pretraining and post-training confidence levels. Program development resulted in recruitment of a variety of career backgrounds for enrollment in both our ATT and BTT workshops. The workshops were run by local physicians from a wide spectrum of medical specialties and previously ATT-trained police officials. Statistically significant improvements in clinical confidence across all curricular topics for ATT and BTT protocols were identified (P < 0.0001). In addition, improvement in confidence after BTT training was similar in Jodhpur compared with Jaipur. These results suggest a promising level of reliability and reproducibility across different geographic areas in rapidly developing settings. Program expansion can offer an exponential growth in the training rate of medical first responders, which can help curb the trauma-related mortality in rapidly developing economies. Future directions will include clinical competency assessments and further progressive differentiation into higher tiers of trauma expertise. Published by Elsevier Inc.

A method of multiplex PCR for detection of field released Beauveria bassiana, a fungal entomopathogen applied for pest management in jute (Corchorus olitorius).

PubMed

Biswas, Chinmay; Dey, Piyali; Gotyal, B S; Satpathy, Subrata

2015-04-01

The fungal entomopathogen Beauveria bassiana is a promising biocontrol agent for many pests. Some B. bassiana strains have been found effective against jute pests. To monitor the survival of field released B. bassiana a rapid and efficient detection technique is essential. Conventional methods such as plating method or direct culture method which are based on cultivation on selective media followed by microscopy are time consuming and not so sensitive. PCR based methods are rapid, sensitive and reliable. A single primer PCR may fail to amplify some of the strains. However, multiplex PCR increases the possibility of detection as it uses multiple primers. Therefore, in the present investigation a multiplex PCR protocol was developed by multiplexing three primers SCA 14, SCA 15 and SCB 9 to detect field released B. bassiana strains from soil as well as foliage of jute field. Using our multiplex PCR protocol all the five B. bassiana strains could be detected from soil and three strains viz., ITCC 6063, ITCC 4563 and ITCC 4796 could be detected even from the crop foliage after 45 days of spray.

Continuous passive motion and physical therapy (CPM) versus physical therapy (PT) versus delayed physical therapy (DPT) after surgical release for elbow contractures; a study protocol for a prospective randomized controlled trial.

PubMed

Viveen, Jetske; Doornberg, Job N; Kodde, Izaak F; Goossens, Pjotr; Koenraadt, Koen L M; The, Bertram; Eygendaal, Denise

2017-11-22

The elbow is prone to stiffness after trauma. To regain functional elbow motion several conservative- and surgical treatment options are available. Conservative treatment includes physical therapy, intra-articular injections with corticosteroids and a static progressive or dynamic splinting program. If conservative treatment fails, an operative release of the posttraumatic stiff elbow is often performed. The best Evidence-Based rehabilitation protocol for patients after an operative release is unknown to date and differs per surgeon, hospital and country. Options include early- or delayed motion supervised by a physical therapist, immediate continuous passive motion (CPM), (night) splinting and a static progressive or dynamic splinting program. The SET-Study (Stiff Elbow Trial) is a single-centre, prospective, randomized controlled trial. The primary objective of this study is to compare the active Range of Motion (ROM) (flexion arc and rotational arc) twelve months after surgery between three groups. The first group will receive in-hospital CPM in combination with early motion Physical Therapy (PT) supervised by a physical therapist, the second group will receive only in-hospital early motion PT supervised by a physical therapist and the third group will receive outpatient supervised PT from postoperative day seven till ten. Secondary outcome measures will be Patient Reported Outcome Measures (PROMs) including the Mayo Elbow Performance Score (MEPS), the Oxford Elbow Score (OES), the quick Disabilities of Arm, Shoulder and Hand (qDASH) score, Visual Analogue pain Scale in rest and activity (VAS), Pain Catastrophizing Scale (PCS), the Short Form (SF)-36, the Centre for Epidemiological Studies Depression Scale Revised (CESD-R) and the Work Rehabilitation Questionnaire (WORQ) for the upper limb. A successful completion of this trial will provide evidence on the best rehabilitation protocol in order to (re)gain optimal motion after surgical release of the stiff elbow. The trial is registered at the Dutch Trial Register: NTR6067 , 31-8-2016.

In situ green synthesis of antimicrobial carboxymethyl chitosan–nanosilver hybrids with controlled silver release

PubMed Central

Huang, Siqi; Yu, Zhiming; Zhang, Yang; Qi, Chusheng; Zhang, Shifeng

2017-01-01

In order to fabricate antimicrobial carboxymethyl chitosan–nanosilver (CMC-Ag) hybrids with controlled silver release, this study demonstrated comparable formation via three synthetic protocols: 1) carboxymethyl chitosan (CMC) and glucose (adding glucose after AgNO3), 2) CMC and glucose (adding glucose before AgNO3), and 3) CMC only. Under principles of green chemistry, the synthesis was conducted in an aqueous medium exposed to microwave irradiation for 10 minutes with nontoxic chemicals. The structure and formation mechanisms of the three CMC-Ag hybrids were explored using X-ray diffraction, ultraviolet-visible spectroscopy, transmission electron microscopy, and Fourier-transform infrared analyses. Additionally, antimicrobial activity and in vitro silver release of the three synthesized hybrids were investigated in detail. The results revealed that a large number of stable, uniform, and small silver nanoparticles (AgNPs) were synthesized in situ on CMC chains via protocol 1. AgNPs were well dispersed with narrow size distribution in the range of 6–20 nm, with mean diameter only 12.22±2.57 nm. The addition of glucose resulted in greater AgNP synthesis. The order of addition of glucose and AgNO3 significantly affected particle size and size distribution of AgNPs. Compared to CMC alone and commercially available AgNPs, the antimicrobial activities of three hybrids were significantly improved. Of the three hybrids, CMC-Ag1 synthesized via protocol 1 exhibited better antimicrobial activity than CMC-Ag2 and CMC-Ag3, and showed more effective inhibition of Staphylococcus aureus than Escherichia coli. Due to strong coordination and electrostatic interactions between CMC and silver and good steric protection provided by CMC, CMC-Ag1 displayed stable and continuous silver release and better performance in retaining silver for prolonged periods than CMC-Ag2 and CMC-Ag3. PMID:28458539

A Draft Protocol for Detecting Possible Biohazards in Martian Samples Returned to Earth

NASA Technical Reports Server (NTRS)

Viso, M.; DeVincenzi, D. L.; Race, M. S.; Schad, P. J.; Stabekis, P. D.; Acevedo, S. E.; Rummel, J. D.

2002-01-01

In preparation for missions to Mars that will involve the return of samples, it is necessary to prepare for the safe receiving, handling, testing, distributing, and archiving of martian materials here on Earth. Previous groups and committees have studied selected aspects of sample return activities, but a specific protocol for handling and testing of returned -=1 samples from Mars remained to be developed. To refine the requirements for Mars sample hazard testing and to develop criteria for the subsequent release of sample materials from precautionary containment, NASA Planetary Protection Officer, working in collaboration with CNES, convened a series of workshops to produce a Protocol by which returned martian sample materials could be assessed for biological hazards and examined for evidence of life (extant or extinct), while safeguarding the samples from possible terrestrial contamination. The Draft Protocol was then reviewed by an Oversight and Review Committee formed specifically for that purpose and composed of senior scientists. In order to preserve the scientific value of returned martian samples under safe conditions, while avoiding false indications of life within the samples, the Sample Receiving Facility (SRF) is required to allow handling and processing of the Mars samples to prevent their terrestrial contamination while maintaining strict biological containment. It is anticipated that samples will be able to be shipped among appropriate containment facilities wherever necessary, under procedures developed in cooperation with international appropriate institutions. The SRF will need to provide different types of laboratory environments for carrying out, beyond sample description and curation, the various aspects of the protocol: Physical/Chemical analysis, Life Detection testing, and Biohazard testing. The main principle of these tests will be described and the criteria for release will be discussed, as well as the requirements for the SRF and its personnel.

The use of a photoionization detector to detect harmful volatile chemicals by emergency personnel

PubMed Central

Patel, Neil D; Fales, William D; Farrell, Robert N

2009-01-01

Objective The objective of this investigation was to determine if a photoionization detector (PID) could be used to detect the presence of a simulated harmful chemical on simulated casualties of a chemical release. Methods A screening protocol, based on existing radiation screening protocols, was developed for the purposes of the investigation. Three simulated casualties were contaminated with a simulated chemical agent and two groups of emergency responders were involved in the trials. The success–failure ratio of the participants was used to judge the performance of the PID in this application. Results A high success rate was observed when the screening protocol was properly adhered to (97.67%). Conversely, the success rate suffered when participants deviated from the protocol (86.31%). With one exception, all failures were noted to have been the result of a failure to correctly observe the established screening protocol. Conclusions The results of this investigation indicate that the PID may be an effective screening tool for emergency responders. However, additional study is necessary to both confirm the effectiveness of the PID and refine the screening protocol if necessary. PMID:27147829

Oral contraceptive pretreatment does not improve outcome in microdose gonadotrophin-releasing hormone agonist protocol among poor responder intracytoplasmic sperm injection patients.

PubMed

Duvan, Candan Iltemir; Berker, Bulent; Turhan, Nilgun Ozturk; Satiroglu, Hakan

2008-01-01

To compare oral contraceptive (OC) pretreatment plus microdose GnRH-a in flare-up protocol and non-OC microdose GnRH-a in flare-up protocol among poor responder ICSI patients. A retrospective analysis of poor responder ICSI patients. Patients were divided into two groups according to used microdose protocol. Precycle treatment with OC followed by follicular phase administration of 40 microg s.c. leuprolide acetate (LA) every 12 h beginning on after 2 day pill-free period and rFSH administration was begun on the third day of LA administration (OC-Group, n=26). Alternatively on day 2 after menses, patients were administered similar stimulation regime (non-OC Group, n=27). There were no significant differences between groups in the number of oocytes, peak estradiol levels, endometrial thickness, fertilization rates and embryo quality. Implantations and pregnancy rates per embryo transfer were similar. OC pretreatment plus microdose GnRHa in flare-up protocol does not offer advantages over non-OC microdose GnRHa in flare-up protocol among poor responder ICSI patients.

National Human Trafficking Initiatives: Dimensions of Policy Diffusion1

PubMed Central

Yoo, Eun-hye; Boyle, Elizabeth Heger

2014-01-01

The implementation of criminal law involves formal law enforcement, education and public outreach aimed at preventing criminal activity, and providing services for victims. Historically, quantitative research on global trends has tended to focus on a single policy dimension, potentially masking the unique factors that affect the diffusion of each policy dimension independently. Using an ordered-probit model to analyze new human trafficking policy data on national prosecution, prevention, and victim-protection efforts, we find that global ties and domestic interest groups matter more in areas where international law is less defined. While prosecution, officially mandated by the Trafficking Protocol, was relatively impervious to global ties and domestic interest groups, both trafficking prevention and victim protection were associated with these factors. Our findings also suggest that fear of repercussions is not a major driver of state actions to combat trafficking—neither ratification of the Trafficking Protocol nor levels of United States aid were associated with greater implementation of anti-trafficking measures. PMID:26538806

National Human Trafficking Initiatives: Dimensions of Policy Diffusion.

PubMed

Yoo, Eun-Hye; Boyle, Elizabeth Heger

2015-01-01

The implementation of criminal law involves formal law enforcement, education and public outreach aimed at preventing criminal activity, and providing services for victims. Historically, quantitative research on global trends has tended to focus on a single policy dimension, potentially masking the unique factors that affect the diffusion of each policy dimension independently. Using an ordered-probit model to analyze new human trafficking policy data on national prosecution, prevention, and victim-protection efforts, we find that global ties and domestic interest groups matter more in areas where international law is less defined. While prosecution, officially mandated by the Trafficking Protocol, was relatively impervious to global ties and domestic interest groups, both trafficking prevention and victim protection were associated with these factors. Our findings also suggest that fear of repercussions is not a major driver of state actions to combat trafficking-neither ratification of the Trafficking Protocol nor levels of United States aid were associated with greater implementation of anti-trafficking measures.

A field investigation of a modified intravaginal progesterone releasing device and oestradiol benzoate based ovulation synchronisation protocol designed for fixed-time artificial insemination of Brahman heifers.

PubMed

Edwards, S A A; Boe-Hansen, G B; Satake, N; Chandra, K; McGowan, M R

2015-09-01

Pregnancy rates (PR) to fixed-time AI (FTAI) in Brahman heifers were compared after treatment with a traditional oestradiol-based protocol (OPO-8) or a modified protocol (OPO-6) where the duration of intravaginal progesterone releasing device (IPRD) was reduced from 8 to 6 days, and the interval from IPRD removal to oestradiol benzoate (ODB) was increased from 24 to 36 h. Rising 2 yo heifers on Farm A: (n = 238 and n = 215; two consecutive days AI); B (n = 271); and C (n = 393) were allocated to OPO-8 or OPO-6. An IPRD was inserted and 1mg ODB i.m. on Day 0 for OPO-8 heifers and Day 2 for OPO-6 heifers. On Day 8, the IPRD was removed and 500 μg cloprostenol i.m. At 24h, for OPO-8 heifers, and 36 h, for OPO-6 heifers, post IPRD removal all heifers received 1mg ODB i.m. FTAI was conducted at 54 and 72 h post IPRD removal for OPO-8 and OPO-6 heifers. At Farm A, OPO-6 heifers, AI on the second day, the PR was 52.4% to FTAI (P = 0.024) compared to 36.8% for OPO-8 heifers. However, no differences were found between OPO-8 and OPO-6 protocols at Farm A (first day of AI) (39.9 vs. 35.7%), or Farms B (26.2 vs. 35.4%) and C (43.2% vs. 40.3%). Presence of a corpus luteum at IPRD insertion affected PR to FTAI (43.9% vs. 28.8%; P < 0.001). This study has shown that the modified ovulation synchronisation protocol OPO-6 may be a viable alternative to the OPO-8 protocol for FTAI in B. indicus heifers. Copyright © 2015 Elsevier B.V. All rights reserved.

A reliable protocol for the isolation of viable, chondrogenically differentiated human mesenchymal stem cells from high-density pellet cultures.

PubMed

Ullah, Mujib; Hamouda, Houda; Stich, Stefan; Sittinger, Michael; Ringe, Jochen

2012-12-01

Administration of chondrogenically differentiated mesenchymal stem cells (MSC) is discussed as a promising approach for the regenerative treatment of injured or diseased cartilage. The high-density pellet culture is the standard culture for chondrogenic differentiation, but cells in pellets secrete extracellular matrix (ECM) that they become entrapped in. Protocols for cell isolation from pellets often result in cell damage and dedifferentiation towards less differentiated MSC. Therefore, our aim was to develop a reliable protocol for the isolation of viable, chondrogenically differentiated MSC from high-density pellet cultures. Human bone marrow MSC were chondrogenically stimulated with transforming growth factor-β3, and the cartilaginous structure of the pellets was verified by alcian blue staining of cartilage proteoglycans, antibody staining of cartilage collagen type II, and quantitative real-time reverse-transcription polymerase chain reaction of the marker genes COL2A1 and SOX9. Trypsin and collagenases II and P were tested alone or in combination, and for different concentrations and times, to find a protocol for optimized pellet digestion. Whereas trypsin was not able to release viable cells, 90-min digestion with 300 U of collagenase II, 20 U of collagenase P, and 2 mM CaCl2 worked quite well and resulted in about 2.5×10(5) cells/pellet. The protocol was further optimized for the separation of released cells and ECM from each other. Cells were alcian blue and collagen type II positive and expressed COL2A1 and SOX9, verifying a chondrogenic character. However, they had different morphological shapes. The ECM was also uniformly alcian blue and collagen type II positive but showed different organizational and structural forms. To conclude, our protocol allows the reliable isolation of a defined number of viable, chondrogenically differentiated MSC from high-density pellet cultures. Such cells, as well as the ECM components, are of interest as research tools and for cartilage tissue engineering.

Quarantine Controversy: Kaci Hickox v. Governor Chris Christie.

PubMed

Gatter, Robert

2016-05-01

Nurse Kaci Hickox is among the "Ebola Fighters" honored by Time magazine as its 2014 Person of the Year, having treated Ebola patients in Sierra Leone while volunteering with Médecins Sans Frontieres. When she returned to the United States in October 2014, she was quarantined in New Jersey for three days before returning home to Maine under the terms of a negotiated release. A year later, in October 2015, Hickox filed suit in federal court against Governor Chris Christie and New Jersey health officials, claiming that the quarantine violated her civil rights. Her complaint asserts that New Jersey officials lacked the authority to quarantine her because she did not pose a significant risk of transmission. The lawsuit raises important questions about disease-transmission risk, the inability of science to rule out certain theoretical risks, and the state's power to quarantine. It also demonstrates that population health depends on respecting individual liberty and using the best available epidemiological data to set public health policy. © 2016 The Hastings Center.

On the experimental approaches for the assessment of the release of engineered nanomaterials from nanocomposites by physical degradation processes

NASA Astrophysics Data System (ADS)

Blázquez, M.; Egizabal, A.; Unzueta, I.

2014-08-01

The LIFE+ Project SIRENA, Simulation of the release of nanomaterials from consumer products for environmental exposure assessment, (LIFE11 ENV/ES/596) has set up a Technological Surveillance System (TSS) to trace technical references at worldwide level related to nanocomposites and the release from nanocomposites. So far a total of seventy three items of different nature (from peer reviewed articles to presentations and contributions to congresses) have been selected and classified as "nanomaterials release simulation technologies". In present document, different approaches for the simulation of different life cycle stages through the physical degradation of polymer nanocomposites at laboratory scale are assessed. In absence of a reference methodology, the comparison of the different protocols used still remains a challenge.