GOES Satellite Observations for the FIRE/SRB Wisconsin Experiment Region from October 11 Through November 2, 1986

NASA Technical Reports Server (NTRS)

Whitlock, Charles H.; T R. acraitch, Eric J.

1987-01-01

A map, concise tables, and satellite images are presented which show ground-site locations, GOES visible/infrared instrument counts above each site, and cloud spatial distribution for the experiment region from 11 October through 2 November 1986. The cloud images are presented near times of the afternoon NOAA-9 satellite overpasses in order to provide a qualitative aid in the interpretation of TOVS, AVHRR, and heat budget data during the FIRE/SRB experiment.

An Ever Present Danger: A Concise History of British Military Operations on the North-West Frontier, 1849-1947 (Occasional Paper, Number 33)

DTIC Science & Technology

2010-06-01

belong almost exclusively to the trans-border Pashtun tribes. As Thomas H. Johnson and M. Chris Mason have pointed out; “The implica- 2 tions of the...Moreman, The Army in India and the Development of Frontier Warfare, 1849–1947 (London: Macmillan Press Ltd., 1998), 240. 4. Thomas H. Johnson and M...time they confronted the Pashtun tribes of the North-West Frontier. 14 Notes 1. Barbara D. Metcalf and Thomas R. Metcalf, A Concise History

Monte Carlo analysis of uncertainty propagation in a stratospheric model. 1: Development of a concise stratospheric model

NASA Technical Reports Server (NTRS)

Rundel, R. D.; Butler, D. M.; Stolarski, R. S.

1977-01-01

A concise model has been developed to analyze uncertainties in stratospheric perturbations, yet uses a minimum of computer time and is complete enough to represent the results of more complex models. The steady state model applies iteration to achieve coupling between interacting species. The species are determined from diffusion equations with appropriate sources and sinks. Diurnal effects due to chlorine nitrate formation are accounted for by analytic approximation. The model has been used to evaluate steady state perturbations due to injections of chlorine and NO(X).

Geometric Design Laboratory Fact Sheet

DOT National Transportation Integrated Search

2006-08-02

This fact sheet provides concise information about the Geometric Design Laboratory (GDL) at the Turner-Fairbank Highway Research Center. The mission of the GDL is to provide technical support to the Federal Highway Administration's Office of Safety R...

Taiwan: Background Notes Series.

ERIC Educational Resources Information Center

Reams, Joanne Reppert

Concise background information on Taiwan is provided. The publication begins with a profile of Taiwan, discussing the people, geography, political establishment, and economy. A map of the country is provided. The bulk of the publication then provides more detailed information on Taiwan's people, geography, history, administration, political…

20 CFR 30.720 - How can an excluded provider request a hearing?

Code of Federal Regulations, 2010 CFR

2010-04-01

... shall contain: (a) A concise notice of the issues on which the provider desires to give evidence at the... medical standards, medical ethics or medical regulation for an advisory opinion from a competent...

20 CFR 10.820 - How can an excluded provider request a hearing?

Code of Federal Regulations, 2010 CFR

2010-04-01

... named under § 10.818(f) and shall contain: (a) A concise notice of the issues on which the provider... questions concerning professional medical standards, medical ethics or medical regulation for an advisory...

Describing the dynamics of processes consisting simultaneously of Poissonian and non-Poissonian kinetics

NASA Astrophysics Data System (ADS)

Eule, S.; Friedrich, R.

2013-03-01

Dynamical processes exhibiting non-Poissonian kinetics with nonexponential waiting times are frequently encountered in nature. Examples are biochemical processes like gene transcription which are known to involve multiple intermediate steps. However, often a second process, obeying Poissonian statistics, affects the first one simultaneously, such as the degradation of mRNA in the above example. The aim of the present article is to provide a concise treatment of such random systems which are affected by regular and non-Poissonian kinetics at the same time. We derive the governing master equation and provide a controlled approximation scheme for this equation. The simplest approximation leads to generalized reaction rate equations. For a simple model of gene transcription we solve the resulting equation and show how the time evolution is influenced significantly by the type of waiting time distribution assumed for the non-Poissonian process.

Detailed Facility Report Data Dictionary | ECHO | US EPA

EPA Pesticide Factsheets

The Detailed Facility Report Data Dictionary provides users with a list of the variables and definitions that have been incorporated into the Detailed Facility Report. The Detailed Facility Report provides a concise enforcement and compliance history for a facility.

Concise Catalog of Deep-Sky Objects

NASA Astrophysics Data System (ADS)

Finlay, Warren H.

This book is intended to give a concise summary of some of the more interesting astrophysical facts that are known about objects commonly observed by amateur astronomers. Pondering this information while viewing an object in the field has added a new level to the author's enjoyment of deep-sky observing, and it is hoped this information will be similarly enjoyed by other amateur astronomers. The book is not intended to be read cover to cover, but rather is designed so that each object entry can be read individually one at a time and in no particular order, perhaps while at the eyepiece.

Highly Enantioselective Rhodium-Catalyzed Addition of Arylboroxines to Simple Aryl Ketones: Efficient Synthesis of Escitalopram.

PubMed

Huang, Linwei; Zhu, Jinbin; Jiao, Guangjun; Wang, Zheng; Yu, Xingxin; Deng, Wei-Ping; Tang, Wenjun

2016-03-24

Highly enantioselective additions of arylboroxines to simple aryl ketones have been achieved for the first time with a Rh/(R,R,R,R)-WingPhos catalyst, thus providing a range of chiral diaryl alkyl carbinols with excellent ee values and yields. (R,R,R,R)-WingPhos has been proven to be crucial for the high reactivity and enantioselectivity. The method has enabled a new, concise, and enantioselective synthesis of the antidepressant drug escitalopram. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Concise Stereocontrolled Formal Synthesis of (±)-Quinine and Total Synthesis of (±)-7-Hydroxyquinine via Merged Morita-Baylis-Hillman-Tsuji-Trost Cyclization

PubMed Central

Webber, Peter; Krische, Michael J.

2010-01-01

Concise stereoselective syntheses of (±)-quinine and (±)-7-hydroxyquinine are achieved using a catalytic enone cycloallylation that combines the nucleophilic features of the Morita-Baylis-Hillman reaction and the electrophilic features of the Tsuji-Trost reaction. Cyclization of enone-allyl carbonate 11 delivers the product of cycloallylation 13 in 68% yield. Diastereoselective conjugate reduction of the enone 13 (>20:1 dr) followed by exchange of N-protecting groups provides the saturated N-Boc-protected methyl ketone 19, which upon aldol dehydration provides quinoline containing enone 15, possessing all carbon atoms of quinine. Exposure of ketone 15 to L-selectride enables diastereoselective carbonyl reduction (>20:1 dr) to furnish the allylic alcohol 16. Stereoselective hydroxyl-directed epoxidation using an oxovanadium catalyst modified by N-hydroxy-N-Me-pivalamide delivers epoxide 17 (17:1 dr). Cyclization of the resulting amine-epoxide 17 provides (±)-7-hydroxyquinine in 13 steps and 11% overall yield from aminoacetaldehyde diethyl acetal. Notably, highly stereoselective formation of five contiguous stereocenters is achieved through a series of 1,2-asymmetric induction events. A formal synthesis of (±)-quinine is achieved upon deoxygenation of the N-Cbz-protected allylic acetate 22 to provide olefin 23, which previously has been converted to quinine. Thus, (±)-quinine is accessible in 16 steps and 4% overall yield from commercial aminoacetaldehyde diethyl acetal, making this route the most concise approach to quinine, to date. PMID:18989927

Procedures For Microbial-Ecology Laboratory

NASA Technical Reports Server (NTRS)

Huff, Timothy L.

1993-01-01

Microbial Ecology Laboratory Procedures Manual provides concise and well-defined instructions on routine technical procedures to be followed in microbiological laboratory to ensure safety, analytical control, and validity of results.

Scabies.

PubMed

Bielan, B

2001-08-01

The "Clinical Snapshot" series provides a concise examination of a clinical presentation including history, treatment, patient education, and nursing measures. Using the format here, you are invited to submit your "Clinical Snapshot" to Dermatology Nursing.

Concise Review: Endothelial Progenitor Cells in Regenerative Medicine: Applications and Challenges

PubMed Central

Chong, Mark Seow Khoon; Ng, Wei Kai

2016-01-01

Endothelial progenitor cells (EPCs) are currently being studied as candidate cell sources for revascularization strategies. Significant advances have been made in understanding the biology of EPCs, and preclinical studies have demonstrated the vasculogenic, angiogenic, and beneficial paracrine effects of transplanted EPCs in the treatment of ischemic diseases. Despite these promising results, widespread clinical acceptance of EPCs for clinical therapies remains hampered by several challenges. The present study provides a concise summary of the different EPC populations being studied for ischemic therapies and their known roles in the healing of ischemic tissues. The challenges and issues surrounding the use of EPCs and the current strategies being developed to improve the harvest efficiency and functionality of EPCs for application in regenerative medicine are discussed. Significance Endothelial progenitor cells (EPCs) have immense clinical value for cardiovascular therapies. The present study provides a concise description of the EPC subpopulations being evaluated for clinical applications. The current major lines of investigation involving preclinical and clinical evaluations of EPCs are discussed, and significant gaps limiting the translation of EPCs are highlighted. The present report could be useful for clinicians and clinical researchers with interests in ischemic therapy and for basic scientists working in the related fields of tissue engineering and regenerative medicine. PMID:26956207

The disruption management model.

PubMed

McAlister, James

2011-10-01

Within all organisations, business continuity disruptions present a set of dilemmas that managers may not have dealt with before in their normal daily duties. The disruption management model provides a simple but effective management tool to enable crisis management teams to stay focused on recovery in the midst of a business continuity incident. The model has four chronological primary headlines, which steer the team through a quick-time crisis decision-making process. The procedure facilitates timely, systematic, rationalised and justified decisions, which can withstand post-event scrutiny. The disruption management model has been thoroughly tested within an emergency services environment and is proven to significantly support clear and concise decision making in a business continuity context.

GAPIT: genome association and prediction integrated tool.

PubMed

Lipka, Alexander E; Tian, Feng; Wang, Qishan; Peiffer, Jason; Li, Meng; Bradbury, Peter J; Gore, Michael A; Buckler, Edward S; Zhang, Zhiwu

2012-09-15

Software programs that conduct genome-wide association studies and genomic prediction and selection need to use methodologies that maximize statistical power, provide high prediction accuracy and run in a computationally efficient manner. We developed an R package called Genome Association and Prediction Integrated Tool (GAPIT) that implements advanced statistical methods including the compressed mixed linear model (CMLM) and CMLM-based genomic prediction and selection. The GAPIT package can handle large datasets in excess of 10 000 individuals and 1 million single-nucleotide polymorphisms with minimal computational time, while providing user-friendly access and concise tables and graphs to interpret results. http://www.maizegenetics.net/GAPIT. zhiwu.zhang@cornell.edu Supplementary data are available at Bioinformatics online.

Guide to cement-based integrated pavement solutions.

DOT National Transportation Integrated Search

2011-08-01

This guide provides a clear, concise, and cohesive presentation of cement-bound materials options for 10 : specific engineering pavement applications: new concrete pavements, concrete overlays, pervious concrete, : precast pavements, roller-compacted...

Vascular complications of transcatheter aortic valve replacement: A concise literature review

PubMed Central

Chaudhry, Muhammad Ali; Sardar, Muhammad Rizwan

2017-01-01

Transcatheter aortic valve replacement (TAVR) is a relatively newer therapeutic modality which offers a promising alternative to surgical aortic valve replacement for patients with prohibitive, high and intermediate surgical risk. The increasing trend to pursue TAVR in these patients has also led to growing awareness of the associated potential vascular complications. The significant impact of these complications on eventual clinical outcome and mortality makes prompt recognition and timely management a critical factor in TAVR patients. We hereby present a concise review with emphasis on diverse vascular complications associated with TAVR and their effective management to improve overall clinical outcomes. PMID:28824787

Attitudes and Action.

ERIC Educational Resources Information Center

Glander, Molly H.; O'Donnell, William J.

This handbook provides sexual information for college students. Though designed for students at North Carolina State University, it is a good model for similar publications on other campuses. The booklet begins by defining different forms of sexual activity--solo, casual, relational, and procreational. Other sections provide concise information on…

Deconstructing time

NASA Astrophysics Data System (ADS)

Purcell, Conor

2018-05-01

Carlo Rovelli, best-selling author of Seven Brief Lessons on Physics, is back with a new book, The Order of Time. This latest venture offers insight into the notion of time, including narratives on how our understanding of the concept has changed from antiquity to the present, as well as a concise update on how time is understood today through the lens of quantum mechanics.

An overview of longitudinal data analysis methods for neurological research.

PubMed

Locascio, Joseph J; Atri, Alireza

2011-01-01

The purpose of this article is to provide a concise, broad and readily accessible overview of longitudinal data analysis methods, aimed to be a practical guide for clinical investigators in neurology. In general, we advise that older, traditional methods, including (1) simple regression of the dependent variable on a time measure, (2) analyzing a single summary subject level number that indexes changes for each subject and (3) a general linear model approach with a fixed-subject effect, should be reserved for quick, simple or preliminary analyses. We advocate the general use of mixed-random and fixed-effect regression models for analyses of most longitudinal clinical studies. Under restrictive situations or to provide validation, we recommend: (1) repeated-measure analysis of covariance (ANCOVA), (2) ANCOVA for two time points, (3) generalized estimating equations and (4) latent growth curve/structural equation models.

22 CFR 216.9 - Bilateral and multilateral studies and concise reviews of environmental issues.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Bilateral and multilateral studies and concise... DEVELOPMENT ENVIRONMENTAL PROCEDURES § 216.9 Bilateral and multilateral studies and concise reviews of... or multilateral environmental studies, relevant or related to the proposed action, prepared by the...

22 CFR 216.9 - Bilateral and multilateral studies and concise reviews of environmental issues.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Bilateral and multilateral studies and concise... DEVELOPMENT ENVIRONMENTAL PROCEDURES § 216.9 Bilateral and multilateral studies and concise reviews of... or multilateral environmental studies, relevant or related to the proposed action, prepared by the...

Understanding Emotional Development: Helping Early Childhood Providers Better Support Families

ERIC Educational Resources Information Center

Edwards, Nicole Megan

2012-01-01

This article is intended to provide early childhood providers with a concise overview of emerging emotional development in young children (birth-5), the important role of primary caregivers, and the link between parenting, emotional development, and behavior. Specific suggestions that have been shared with urban Head Start mothers are offered,…

Drug-Free Schools & Communities: Program Planning Guidelines & Community Inventory.

ERIC Educational Resources Information Center

Montana State Board of Crime Control, Helena.

This book is designed to provide Montana communities with the most current research-based information available concerning drug and alcohol prevention/education program planning. It also provides a concise overview of the programs being conducted in various Montana communities. It is intended for use as a resource manual, to provide readers with…

CSC Tip Sheets: Action Checklists

EPA Pesticide Factsheets

Learn how to use action checklists to motivate behavior change by providing a clear and concise list of activities that community members and organizations can use to reduce their carbon footprint and achieve other sustainability goals.

PHYTOREMEDIATION OF CONTAMINATED SOIL AND GROUND WATER AT HAZARDOUS WASTE SITES

EPA Science Inventory

The purpose of this issue paper is to provide a concise discussion of the processes associated with the use of phytoremediation as a cleanup or containment technique for remediation of hazardous waste sites. Introductory material on plant processes is provided. The different fo...

Astronaut training manual

NASA Technical Reports Server (NTRS)

Coleman, E. A.

1980-01-01

Scientific information from previous space flights, space medicine, exercise physiology, and sports medicine was used to prepare a physical fitness manual suitable for use by members of the NASA astronaut population. A variety of scientifically valid exercise programs and activities suitable for the development of physical fitness are provided. Programs, activities, and supportive scientific data are presented in a concise, easy to read format so as to permit the user to select his or her mode of training with confidence and devote time previously spent experimenting with training routines to preparation for space flight. The programs and activities included were tested and shown to be effective and enjoyable.

Total synthesis and biological investigation of (-)-promysalin.

PubMed

Steele, Andrew D; Knouse, Kyle W; Keohane, Colleen E; Wuest, William M

2015-06-17

Compounds that specifically target pathogenic bacteria are greatly needed, and identifying the method by which they act would provide new avenues of treatment. Herein we report the concise, high-yielding total synthesis (eight steps, 35% yield) of promysalin, a natural product that displays antivirulence phenotypes against pathogenic bacteria. Guided by bioinformatics, four diastereomers were synthesized, and the relative and absolute stereochemistries were confirmed by spectral and biological analysis. Finally, we show for the first time that promysalin displays two antivirulence phenotypes: the dispersion of mature biofilms and the inhibition of pyoverdine production, hinting at a unique pathogenic-specific mechanism of action.

PHYTOREMEDIATION OF CONTAMINATED SOIL AND GROUND WATER AT HAZARDOUS WASTE SITES (EPA/540/S-01/500)

EPA Science Inventory

The purpose of this issue paper is to provide a concise discussion of the processes associated with the use of phytoremediation as a cleanup or containment technique for remediation of hazardous waste sites. Introductory material on plant processes is provided. The different form...

Swedish: The Swedish Language in Education in Finland. Regional Dossiers Series.

ERIC Educational Resources Information Center

Ostern, Anna Lena

This regional dossier aims to provide concise, descriptive information and basic educational statistics about minority language education in a specific country of the European Union--Finland. Details are provided about the features of the educational system, recent educational policies, divisions of responsibilities, main actors, legal…

Occitan: The Occitan Language in Education in France. Regional Dossiers Series.

ERIC Educational Resources Information Center

Berthoumieux, Michel; Willemsma, Adalgard

This regional dossier aims to provide concise, descriptive information and basic educational statistics about minority language education in a specific region of the European Union--the South of France. Details are provided about the features of the educational system, recent educational policies, divisions of responsibilities, main actors, legal…

Wood machining highlights, 1972 and 1973

Treesearch

Charles W. Mcmillin

1975-01-01

Important wood machining research published during 1972 and 1973 is highlighted to provide the reader with a concise summary of activity in 17 fields of endeavor. The review is based on 427 references and contains 154 citations.

Sustainable concrete pavements : a manual of practice.

DOT National Transportation Integrated Search

2011-08-01

Developed as a more detailed follow-up to a 2009 briefing document, Building Sustainable Pavement with Concrete, this guide provides a clear, concise, and cohesive discussion of pavement sustainability concepts and of recommended practices for maximi...

Guide for Commenting on NEEDS and IPM

EPA Pesticide Factsheets

Find on this page a document intended to provide guidance on submitting clear, concise, and impactful comments on NEEDS (National Electric Energy Data System), other inputs to the Integrated Planning Model (IPM), or outputs from IPM.

Wood Machining Highlights, 1972 and 1973

Treesearch

C.W. McMillin

1975-01-01

Important wood machining research published during 1972 and 1973 is highlighted to provide the reader with a concise summary of activity in 17 fields of endeavor. The review is based on 427 references and contains 154 citations.

Developing and Modifying Behavioral Coding Schemes in Pediatric Psychology: A Practical Guide

PubMed Central

McMurtry, C. Meghan; Chambers, Christine T.; Bakeman, Roger

2015-01-01

Objectives To provide a concise and practical guide to the development, modification, and use of behavioral coding schemes for observational data in pediatric psychology. Methods This article provides a review of relevant literature and experience in developing and refining behavioral coding schemes. Results A step-by-step guide to developing and/or modifying behavioral coding schemes is provided. Major steps include refining a research question, developing or refining the coding manual, piloting and refining the coding manual, and implementing the coding scheme. Major tasks within each step are discussed, and pediatric psychology examples are provided throughout. Conclusions Behavioral coding can be a complex and time-intensive process, but the approach is invaluable in allowing researchers to address clinically relevant research questions in ways that would not otherwise be possible. PMID:25416837

A Learner-Centered Technique and Clinical Reasoning, Reflection, and Case Presentation Attributes in Athletic Training Students

PubMed Central

Heinerichs, Scott; Vela, Luzita I.; Drouin, Joshua M.

2013-01-01

Context: Providing opportunities to develop clinical decision-making skills, including clinical reasoning, is an important aspect of clinical education. The learner-centered technique of summarizing the history and findings, narrowing the differential, analyzing the differential, probing the instructor about uncertainties, plan management, and selecting an issue for self-directed study (SNAPPS) is used in medicine to express clinical reasoning. Objective: To investigate the effects of SNAPPS on the clinical reasoning, reflection, and 4 case presentation attributes (length, conciseness, case summary, and expression of clinical reasoning) in athletic training students. Design: Randomized controlled clinical trial. Setting: Three undergraduate programs accredited by the Commission on Accreditation of Athletic Training Education. Patients or Other Participants: We randomly assigned 38 athletic training students (17 men, 21 women; age = 21.53 ± 1.18 years, grade point average = 3.25 ± 0.31) who had completed at least 1 year of clinical education and all orthopaedic evaluation coursework to the SNAPPS group or the usual and customary group using a stratification scheme. Intervention(s): The SNAPPS group completed four 45-minute clinical reasoning and case presentation learning modules led by an investigator to learn the SNAPPS technique, whereas the usual and customary group received no formal instruction. Both groups audio recorded all injury evaluations performed over a 2-week period. Main Outcome Measures: Participants completed the Diagnostic Thinking Inventory and Reflection in Learning Scale twice. Case presentations were analyzed for 4 attributes: length, conciseness, case summary, and expression of clinical reasoning. Results: Case presentations were longer (t18.806 = −5.862, P < .001) but were more concise (t32 = 11.297, P < .001) for the SNAPPS group than for the usual and customary group. The SNAPPS group performed better on both the case summary subscale (t32 = 2.857, P = .007) and the clinical reasoning subscale (t25.773 = −14.162, P < .001) than the other group. We found a time effect for Diagnostic Thinking Inventory scores (F1,34 = 6.230, P = .02) but observed no group effects (F1,34 = 0.698, P = .41) or time-by-group interaction (F1,34 = 1.050, P = .31). The Reflection in Learning Scale scores analysis revealed no group-by-time interaction (F1,34 = 1.470, P = .23) and no group (F1,34 = 3.751, P = .06) or time (F1,34 = 0.835, P = .37) effects. Conclusions: The SNAPPS is an effective and feasible clinical education technique for case presentations. This learner-centered technique provides the opportunity for the expression of clinical reasoning skills. PMID:23675796

Adapting Comparative Effectiveness Research Summaries for Delivery to Patients and Providers through a Patient Portal

PubMed Central

McDougald Scott, Amanda M.; Jackson, Gretchen Purcell; Ho, Yun-Xian; Yan, Zhou; Davison, Coda; Rosenbloom, S. Trent

2013-01-01

Despite increases in the scientific evidence for a variety of medical treatments, a gap remains in the adoption of best medical practices. This manuscript describes a process for adapting published summary guides from comparative effectiveness research to render them concise, targeted to audience, and easily actionable; and a strategy for disseminating such evidence to patients and their physicians through a web-based portal and linked electronic health record. This project adapted summary guides about oral medications for adults with type 2 diabetes to a fifth-grade literacy level and modified the resulting materials based on evaluations with the Suitability Assessment of Materials instrument. Focus groups and individual interviews with patients, diabetes providers, and health literacy experts were employed to evaluate and enhance the adapted summary guide. We present the lessons learned as general guidelines for the creation of concise, targeted, and actionable evidence and its delivery to both patients and providers through increasingly prevalent health information technologies. PMID:24551387

Cybernetics and Workshop Design.

ERIC Educational Resources Information Center

Eckstein, Daniel G.

1979-01-01

Cybernetic sessions allow for the investigation of several variables concurrently, resulting in a large volume of input compacted into a concise time frame. Three session questions are reproduced to illustrate the variety of ideas generated relative to workshop design. (Author)

Quantitative evaluation of refolding conditions for a disulfide-bond-containing protein using a concise 18O-labeling technique

PubMed Central

Uchimura, Hiromasa; Kim, Yusam; Mizuguchi, Takaaki; Kiso, Yoshiaki; Saito, Kazuki

2011-01-01

A concise method was developed for quantifying native disulfide-bond formation in proteins using isotopically labeled internal standards, which were easily prepared with proteolytic 18O-labeling. As the method has much higher throughput to estimate the amounts of fragments possessing native disulfide arrangements by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) than the conventional high performance liquid chromatography (HPLC) analyses, it allows many different experimental conditions to be assessed in a short time. The method was applied to refolding experiments of a recombinant neuregulin 1-β1 EGF-like motif (NRG1-β1), and the optimum conditions for preparing native NRG1-β1 were obtained by quantitative comparisons. Protein disulfide isomerase (PDI) was most effective at the reduced/oxidized glutathione ratio of 2:1 for refolding the denatured sample NRG1-β1 with the native disulfide bonds. PMID:21500299

An Overview of Longitudinal Data Analysis Methods for Neurological Research

PubMed Central

Locascio, Joseph J.; Atri, Alireza

2011-01-01

The purpose of this article is to provide a concise, broad and readily accessible overview of longitudinal data analysis methods, aimed to be a practical guide for clinical investigators in neurology. In general, we advise that older, traditional methods, including (1) simple regression of the dependent variable on a time measure, (2) analyzing a single summary subject level number that indexes changes for each subject and (3) a general linear model approach with a fixed-subject effect, should be reserved for quick, simple or preliminary analyses. We advocate the general use of mixed-random and fixed-effect regression models for analyses of most longitudinal clinical studies. Under restrictive situations or to provide validation, we recommend: (1) repeated-measure analysis of covariance (ANCOVA), (2) ANCOVA for two time points, (3) generalized estimating equations and (4) latent growth curve/structural equation models. PMID:22203825

12 CFR 1022.23 - Contents of opt-out notice; consolidated and equivalent notices.

Code of Federal Regulations, 2012 CFR

2012-01-01

... CREDIT REPORTING (REGULATION V) Affiliate Marketing § 1022.23 Contents of opt-out notice; consolidated..., conspicuous, and concise, and must accurately disclose: (i) The name of the affiliate(s) providing the notice. If the notice is provided jointly by multiple affiliates and each affiliate shares a common name...

12 CFR 717.23 - Contents of opt-out notice; consolidated and equivalent notices.

Code of Federal Regulations, 2014 CFR

2014-01-01

... AFFECTING CREDIT UNIONS FAIR CREDIT REPORTING Affiliate Marketing § 717.23 Contents of opt-out notice..., conspicuous, and concise, and must accurately disclose: (i) The name of the affiliate(s) providing the notice. If the notice is provided jointly by multiple affiliates and each affiliate shares a common name...

12 CFR 1022.23 - Contents of opt-out notice; consolidated and equivalent notices.

Code of Federal Regulations, 2013 CFR

2013-01-01

... CREDIT REPORTING (REGULATION V) Affiliate Marketing § 1022.23 Contents of opt-out notice; consolidated..., conspicuous, and concise, and must accurately disclose: (i) The name of the affiliate(s) providing the notice. If the notice is provided jointly by multiple affiliates and each affiliate shares a common name...

12 CFR 717.23 - Contents of opt-out notice; consolidated and equivalent notices.

Code of Federal Regulations, 2011 CFR

2011-01-01

... AFFECTING CREDIT UNIONS FAIR CREDIT REPORTING Affiliate Marketing § 717.23 Contents of opt-out notice..., conspicuous, and concise, and must accurately disclose: (i) The name of the affiliate(s) providing the notice. If the notice is provided jointly by multiple affiliates and each affiliate shares a common name...

12 CFR 717.23 - Contents of opt-out notice; consolidated and equivalent notices.

Code of Federal Regulations, 2012 CFR

2012-01-01

... AFFECTING CREDIT UNIONS FAIR CREDIT REPORTING Affiliate Marketing § 717.23 Contents of opt-out notice..., conspicuous, and concise, and must accurately disclose: (i) The name of the affiliate(s) providing the notice. If the notice is provided jointly by multiple affiliates and each affiliate shares a common name...

12 CFR 717.23 - Contents of opt-out notice; consolidated and equivalent notices.

Code of Federal Regulations, 2013 CFR

2013-01-01

... AFFECTING CREDIT UNIONS FAIR CREDIT REPORTING Affiliate Marketing § 717.23 Contents of opt-out notice..., conspicuous, and concise, and must accurately disclose: (i) The name of the affiliate(s) providing the notice. If the notice is provided jointly by multiple affiliates and each affiliate shares a common name...

12 CFR 1022.23 - Contents of opt-out notice; consolidated and equivalent notices.

Code of Federal Regulations, 2014 CFR

2014-01-01

... CREDIT REPORTING (REGULATION V) Affiliate Marketing § 1022.23 Contents of opt-out notice; consolidated..., conspicuous, and concise, and must accurately disclose: (i) The name of the affiliate(s) providing the notice. If the notice is provided jointly by multiple affiliates and each affiliate shares a common name...

Taking the provider-driven company public: a primer on business and legal issues.

PubMed

Becker, S; Pristave, R J; Liebers, E H

1996-01-01

The article provides a concise review of the critical business and legal characteristics of recent health care-driven initial public offerings. In that regard, the article examines three recent provider-driven companies that have effectuated initial public offerings, and reviews certain of their business fundamentals and the manner in which each handled various legal disclosure issues.

Religion and Multiculturalism in Education.

ERIC Educational Resources Information Center

Alexander, H. A.

1995-01-01

Provides a concise historical overview of theological thinking concerning fundamentalism, absolutism, and relativism. Considers corresponding responses to issues regarding multiculturalism. Concludes that a diversity of viewpoints is necessary for society to learn from its mistakes and progress in a positive fashion. (MJP)

Exploring the Scopes "Monkey" Trial in Dayton, Tennessee: A Guide to People & Places

ERIC Educational Resources Information Center

Cameron, Jacquelyn; Moore, Randy

2015-01-01

Many biology teachers visit Dayton, Tennessee, to experience "ground zero" of the evolution-creationism controversy. This article provides concise descriptions, addresses, and GPS coordinates for the trial-related sites in and around Dayton.

Synthesis of labeled meropenem for the analysis of M. tuberculosis transpeptidases.

PubMed

Kastrinsky, David B; Barry, Clifton E

2010-01-01

A concise synthesis of (14)C labeled meropenem prepared from (14)C dimethylamine hydrochloride is described. Using a similar reaction sequence, the meropenem nucleus was also attached to biotin providing a probe for protein interaction studies.

ITS logical architecture : volume II, process specifications.

DOT National Transportation Integrated Search

1981-07-01

Author's abstract: This report identifies 24 critical issues related to pedestrian and bicycle facilities and programs, summarizes the state-of-the-art on each issue as it is contained in the published literature, and provides a concise commentary on...

Early perinatal diagnosis of mothers at risk of developing post-partum depression--a concise guide for obstetricians, midwives, neonatologists and paediatricians.

PubMed

Ambrosini, Alessandra; Donzelli, Gianpaolo; Stanghellini, Giovanni

2012-07-01

In this article, we tried to provide all those involved in perinatal medicine with a concise guide to detect mothers at risk of developing post-partum depression. Motherhood is a critical situation characterized by role conflicts because conflicts among the role of mother, worker and wife are the norm in the post-partum period and may jeopardize the mother's existence. We have described a kind of personality that is at great risk of developing post-partum depression because of the incapacity to creatively manage situations of role conflict. This personality structure is called typus melancholicus, and we operationally defined its main features: orderliness, conscientiousness, hypernomia/heteronomia and intolerance of ambiguity. We have shown how these mothers may typically behave during pregnancy and early motherhood: they cannot avoid behaving with feverish perfectionism, developing an exaggerated preoccupation towards the unborn child and hostility towards persons and events that are experienced as an obstacle to their search for perfection. They ultra-carefully follow all the steps concerning paediatric check-ups and feel all the responsibility relating to the care of the child, without being able to delegate to someone else or share their feelings. We hope to provide those clinicians who are engaged in the care of pregnant women and their children with a valuable and user-friendly instrument for understanding and making a timely diagnoses of at-risk psychopathological phenomena.

Latest approaches on green chemistry preconcentration methods for trace metal determination in seawater--a review.

PubMed

La Colla, Noelia Soledad; Domini, Claudia Elizabeth; Marcovecchio, Jorge Eduardo; Botté, Sandra Elizabeth

2015-03-15

Evaluation of trace metal levels in seawater samples is undertaken regularly by research groups all over the world, leading to a growing demand for techniques involving fewer toxic reagents, less time-consuming protocols and lower limits of detection. This review focuses on providing a brief but concise description of the latest methodologies developed to this end, outlining the advantages and disadvantages of the various protocols, chelating and dispersive agents and instruments used. Conclusions are drawn on the basis of the articles reviewed, highlighting improvements introduced in order to enhance the performance of the protocols. Copyright © 2014 Elsevier Ltd. All rights reserved.

Generalized fractional diffusion equations for subdiffusion in arbitrarily growing domains

NASA Astrophysics Data System (ADS)

Angstmann, C. N.; Henry, B. I.; McGann, A. V.

2017-10-01

The ubiquity of subdiffusive transport in physical and biological systems has led to intensive efforts to provide robust theoretical models for this phenomena. These models often involve fractional derivatives. The important physical extension of this work to processes occurring in growing materials has proven highly nontrivial. Here we derive evolution equations for modeling subdiffusive transport in a growing medium. The derivation is based on a continuous-time random walk. The concise formulation of these evolution equations requires the introduction of a new, comoving, fractional derivative. The implementation of the evolution equation is illustrated with a simple model of subdiffusing proteins in a growing membrane.

The equations of motion of a secularly precessing elliptical orbit

NASA Astrophysics Data System (ADS)

Casotto, S.; Bardella, M.

2013-01-01

The equations of motion of a secularly precessing ellipse are developed using time as the independent variable. The equations are useful when integrating numerically the perturbations about a reference trajectory which is subject to secular perturbations in the node, the argument of pericentre and the mean motion. Usually this is done in connection with Encke's method to ensure minimal rectification frequency. Similar equations are already available in the literature, but they are either given based on the true anomaly as the independent variable or in mixed mode with respect to time through the use of a supporting equation to track the anomaly. The equations developed here form a complete and independent set of six equations in time. Reformulations both of Escobal's and Kyner and Bennett's equations are also provided which lead to a more concise form.

Developing and modifying behavioral coding schemes in pediatric psychology: a practical guide.

PubMed

Chorney, Jill MacLaren; McMurtry, C Meghan; Chambers, Christine T; Bakeman, Roger

2015-01-01

To provide a concise and practical guide to the development, modification, and use of behavioral coding schemes for observational data in pediatric psychology. This article provides a review of relevant literature and experience in developing and refining behavioral coding schemes. A step-by-step guide to developing and/or modifying behavioral coding schemes is provided. Major steps include refining a research question, developing or refining the coding manual, piloting and refining the coding manual, and implementing the coding scheme. Major tasks within each step are discussed, and pediatric psychology examples are provided throughout. Behavioral coding can be a complex and time-intensive process, but the approach is invaluable in allowing researchers to address clinically relevant research questions in ways that would not otherwise be possible. © The Author 2014. Published by Oxford University Press on behalf of the Society of Pediatric Psychology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Concise Review: Microfluidic Technology Platforms: Poised to Accelerate Development and Translation of Stem Cell-Derived Therapies

PubMed Central

Titmarsh, Drew M.; Chen, Huaying; Glass, Nick R.; Cooper-White, Justin J.

2014-01-01

Stem cells are a powerful resource for producing a variety of cell types with utility in clinically associated applications, including preclinical drug screening and development, disease and developmental modeling, and regenerative medicine. Regardless of the type of stem cell, substantial barriers to clinical translation still exist and must be overcome to realize full clinical potential. These barriers span processes including cell isolation, expansion, and differentiation; purification, quality control, and therapeutic efficacy and safety; and the economic viability of bioprocesses for production of functional cell products. Microfluidic systems have been developed for a myriad of biological applications and have the intrinsic capability of controlling and interrogating the cellular microenvironment with unrivalled precision; therefore, they have particular relevance to overcoming such barriers to translation. Development of microfluidic technologies increasingly utilizes stem cells, addresses stem cell-relevant biological phenomena, and aligns capabilities with translational challenges and goals. In this concise review, we describe how microfluidic technologies can contribute to the translation of stem cell research outcomes, and we provide an update on innovative research efforts in this area. This timely convergence of stem cell translational challenges and microfluidic capabilities means that there is now an opportunity for both disciplines to benefit from increased interaction. PMID:24311699

Randomization to Standard and Concise Informed Consent Forms: Development of Evidence-Based Consent Practices

PubMed Central

Enama, Mary E.; Hu, Zonghui; Gordon, Ingelise; Costner, Pamela; Ledgerwood, Julie E.; Grady, Christine

2012-01-01

Background Consent to participate in research is an important component of the conduct of ethical clinical trials. Current consent practices are largely policy-driven. This study was conducted to assess comprehension of study information and satisfaction with the consent form between subjects randomized to concise or to standard informed consent forms as one approach to developing evidence-based consent practices. Methods Participants (N=111) who enrolled into two Phase I investigational influenza vaccine protocols (VRC 306 and VRC 307) at the NIH Clinical Center were randomized to one of two IRB-approved consents; either a standard or concise form. Concise consents had an average of 63% fewer words. All other aspects of the consent process were the same. Questionnaires about the study and the consent process were completed at enrollment and at the last visit in both studies. Results Subjects using concise consent forms scored as well as those using standard length consents in measures of comprehension (7 versus 7, p=0.79 and 20 versus 21, p=0.13), however, the trend was for the concise consent group to report feeling better informed. Both groups thought the length and detail of the consent form was appropriate. Conclusions Randomization of study subjects to different length IRB-approved consents forms as one method for developing evidence-based consent practices, resulted in no differences in study comprehension or satisfaction with the consent form. A concise consent form may be used ethically in the context of a consent process conducted by well-trained staff with opportunities for discussion and education throughout the study. PMID:22542645

Immune System Toxicity and Immunotoxicity Hazard Identification

EPA Science Inventory

Exposure to chemicals may alter immune system health, increasing the risk of infections, allergy and autoimmune diseases. The chapter provides a concise overview of the immune system, host factors that affect immune system heal, and the effects that xenobiotic exposure may have ...

Best Practices for Effective Poster Design

NASA Astrophysics Data System (ADS)

Star Cartier, Kimberly Michelle; Zhao, Ming; Beatty, Thomas G.; Morehead, Robert C.; Jontof-Hutter, Daniel

2016-01-01

This meta-poster illustrates how good poster design can effectively communicate scientific ideas to a broad professional audience. Inclusion of illustrative fugues supplemented by concise explanations of scientific information will provide a clear overview of your science to aid your oral pitch.

Media: A Pocket Guide.

ERIC Educational Resources Information Center

Arrasjid, Harun; Arrasjid, Dorine Audrey

An attempt has been made to provide a concise but comprehensive guide to instructional media for instructors, students, and teachers. Topics covered include audio learning systems, overhead projection, opaque projection, slide and filmstrip projection, projection surfaces, chalkboards and markboards, graphics, models, duplicating, motion pictures,…

Synthesis of labeled meropenem for the analysis of M. tuberculosis transpeptidases

PubMed Central

Kastrinsky, David B.; Barry, Clifton E.

2009-01-01

A concise synthesis of 14C labeled meropenem prepared from 14C dimethylamine hydrochloride is described. Using a similar reaction sequence, the meropenem nucleus was also attached to biotin providing a probe for protein interaction studies. PMID:20161438

Curriculum Resources.

ERIC Educational Resources Information Center

Thompson, Norma H.

1988-01-01

Discusses an article which presents a concise discussion of secular humanism. Reviews additional materials on censorship from the perspective of the new religious right, the fundamentalists, and public policy and the law. The sources provide background to enhance teaching about secular humanism and textbook censorship. (SLM)

76 FR 14442 - 60-Day Notice of Proposed Information Collection: DS 6561 Pre-Assignment for Overseas Duty for...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-16

... automated collection techniques or other forms of technology. Abstract of proposed collection: The DS 6561 form provides a concise summary of basic medical history, lab tests and physical examination. Since...

The Growth of the Chinese People’s Liberation Army Navy: Impacts and Implications of Regional Naval Expansion

DTIC Science & Technology

2007-12-01

April 2000): 338. 279 Rondo Cameron, A Concise Economic History of the World: From Paleolithic Times to the Present (New York, NY: Oxford...the World: From Paleolithic Times to the Present. New York, NY: Oxford University Press, 1993. 120 Chihiro, Hosoya. “Japan’s Policies Toward

Monitoring groundwater-surface water interaction using time-series and time-frequency analysis of transient three-dimensional electrical resistivity changes

USGS Publications Warehouse

Johnson, Timothy C.; Slater, Lee D.; Ntarlagiannis, Dimitris; Day-Lewis, Frederick D.; Elwaseif, Mehrez

2012-01-01

Time-lapse resistivity imaging is increasingly used to monitor hydrologic processes. Compared to conventional hydrologic measurements, surface time-lapse resistivity provides superior spatial coverage in two or three dimensions, potentially high-resolution information in time, and information in the absence of wells. However, interpretation of time-lapse electrical tomograms is complicated by the ever-increasing size and complexity of long-term, three-dimensional (3-D) time series conductivity data sets. Here we use 3-D surface time-lapse electrical imaging to monitor subsurface electrical conductivity variations associated with stage-driven groundwater-surface water interactions along a stretch of the Columbia River adjacent to the Hanford 300 near Richland, Washington, USA. We reduce the resulting 3-D conductivity time series using both time-series and time-frequency analyses to isolate a paleochannel causing enhanced groundwater-surface water interactions. Correlation analysis on the time-lapse imaging results concisely represents enhanced groundwater-surface water interactions within the paleochannel, and provides information concerning groundwater flow velocities. Time-frequency analysis using the Stockwell (S) transform provides additional information by identifying the stage periodicities driving groundwater-surface water interactions due to upstream dam operations, and identifying segments in time-frequency space when these interactions are most active. These results provide new insight into the distribution and timing of river water intrusion into the Hanford 300 Area, which has a governing influence on the behavior of a uranium plume left over from historical nuclear fuel processing operations.

Catalog of Selected Federal Publications on Illegal Drug and Alcohol Abuse.

ERIC Educational Resources Information Center

National Clearinghouse for Alcohol and Drug Information (DHHS), Rockville, MD.

A concise collection of federal publications in the area of illegal drug and alcohol abuse, this catalog begins with a listing of seven federal clearinghouse, with information on services, user audience, and a contact provided for each. The main part of the document provides briefly annotated information on federal publications organized into the…

12 CFR 41.23 - Contents of opt-out notice; consolidated and equivalent notices.

Code of Federal Regulations, 2011 CFR

2011-01-01

... TREASURY FAIR CREDIT REPORTING Affiliate Marketing § 41.23 Contents of opt-out notice; consolidated and... concise, and must accurately disclose: (i) The name of the affiliate(s) providing the notice. If the notice is provided jointly by multiple affiliates and each affiliate shares a common name, such as “ABC...

12 CFR 41.23 - Contents of opt-out notice; consolidated and equivalent notices.

Code of Federal Regulations, 2012 CFR

2012-01-01

... TREASURY FAIR CREDIT REPORTING Affiliate Marketing § 41.23 Contents of opt-out notice; consolidated and... concise, and must accurately disclose: (i) The name of the affiliate(s) providing the notice. If the notice is provided jointly by multiple affiliates and each affiliate shares a common name, such as “ABC...

12 CFR 41.23 - Contents of opt-out notice; consolidated and equivalent notices.

Code of Federal Regulations, 2013 CFR

2013-01-01

... TREASURY FAIR CREDIT REPORTING Affiliate Marketing § 41.23 Contents of opt-out notice; consolidated and... concise, and must accurately disclose: (i) The name of the affiliate(s) providing the notice. If the notice is provided jointly by multiple affiliates and each affiliate shares a common name, such as “ABC...

12 CFR 571.23 - Contents of opt-out notice; consolidated and equivalent notices.

Code of Federal Regulations, 2013 CFR

2013-01-01

... TREASURY FAIR CREDIT REPORTING Affiliate Marketing § 571.23 Contents of opt-out notice; consolidated and... concise, and must accurately disclose: (i) The name of the affiliate(s) providing the notice. If the notice is provided jointly by multiple affiliates and each affiliate shares a common name, such as “ABC...

12 CFR 41.23 - Contents of opt-out notice; consolidated and equivalent notices.

Code of Federal Regulations, 2014 CFR

2014-01-01

... TREASURY FAIR CREDIT REPORTING Affiliate Marketing § 41.23 Contents of opt-out notice; consolidated and... concise, and must accurately disclose: (i) The name of the affiliate(s) providing the notice. If the notice is provided jointly by multiple affiliates and each affiliate shares a common name, such as “ABC...

12 CFR 571.23 - Contents of opt-out notice; consolidated and equivalent notices.

Code of Federal Regulations, 2011 CFR

2011-01-01

... TREASURY FAIR CREDIT REPORTING Affiliate Marketing § 571.23 Contents of opt-out notice; consolidated and... concise, and must accurately disclose: (i) The name of the affiliate(s) providing the notice. If the notice is provided jointly by multiple affiliates and each affiliate shares a common name, such as “ABC...

12 CFR 571.23 - Contents of opt-out notice; consolidated and equivalent notices.

Code of Federal Regulations, 2014 CFR

2014-01-01

... TREASURY FAIR CREDIT REPORTING Affiliate Marketing § 571.23 Contents of opt-out notice; consolidated and... concise, and must accurately disclose: (i) The name of the affiliate(s) providing the notice. If the notice is provided jointly by multiple affiliates and each affiliate shares a common name, such as “ABC...

12 CFR 571.23 - Contents of opt-out notice; consolidated and equivalent notices.

Code of Federal Regulations, 2012 CFR

2012-01-01

... TREASURY FAIR CREDIT REPORTING Affiliate Marketing § 571.23 Contents of opt-out notice; consolidated and... concise, and must accurately disclose: (i) The name of the affiliate(s) providing the notice. If the notice is provided jointly by multiple affiliates and each affiliate shares a common name, such as “ABC...

The importance of independent chronology in integrating records of past climate change for the 60-8 ka INTIMATE time interval

NASA Astrophysics Data System (ADS)

Brauer, Achim; Hajdas, Irka; Blockley, Simon P. E.; Bronk Ramsey, Christopher; Christl, Marcus; Ivy-Ochs, Susan; Moseley, Gina E.; Nowaczyk, Norbert N.; Rasmussen, Sune O.; Roberts, Helen M.; Spötl, Christoph; Staff, Richard A.; Svensson, Anders

2014-12-01

This paper provides a brief overview of the most common dating techniques applied in palaeoclimate and palaeoenvironmental studies including four radiometric and isotopic dating methods (radiocarbon, 230Th disequilibrium, luminescence, cosmogenic nuclides) and two incremental methods based on layer counting (ice layer, varves). For each method, concise background information about the fundamental principles and methodological approaches is provided. We concentrate on the time interval of focus for the INTIMATE (Integrating Ice core, MArine and TErrestrial records) community (60-8 ka). This dating guide addresses palaeoclimatologists who aim at interpretation of their often regional and local proxy time series in a wider spatial context and, therefore, have to rely on correlation with proxy records obtained from different archives from various regions. For this reason, we especially emphasise scientific approaches for harmonising chronologies for sophisticated and robust proxy data integration. In this respect, up-to-date age modelling techniques are presented as well as tools for linking records by age equivalence including tephrochronology, cosmogenic 10Be and palaeomagnetic variations. Finally, to avoid inadequate documentation of chronologies and assure reliable correlation of proxy time series, this paper provides recommendations for minimum standards of uncertainty and age datum reporting.

A concise history of central venous access.

PubMed

Beheshti, Michael V

2011-12-01

Central venous access has become a mainstay of modern interventional radiology practice. Its history has paralleled and enabled many current medical therapies. This short overview provides an interesting historical perspective of these increasingly common interventional procedures. Copyright © 2011 Elsevier Inc. All rights reserved.

Phytoremediation of Contaminated Soil and Ground Water at Hazardous Waste Sites

EPA Pesticide Factsheets

The purpose of this issue paper is to provide a concise discussion of the processes associated with the use of phytoremediation as a cleanup or containment technique for remediation of hazardous waste sites. Introductory material on plant processes is ...

Theoretical Foundations of Learning Environments. Second Edition

ERIC Educational Resources Information Center

Jonassen, David, Ed.; Land, Susan, Ed.

2012-01-01

"Theoretical Foundations of Learning Environments" provides students, faculty, and instructional designers with a clear, concise introduction to the major pedagogical and psychological theories and their implications for the design of new learning environments for schools, universities, or corporations. Leading experts describe the most…

The Independent Music Teacher: Practice and Preparation.

ERIC Educational Resources Information Center

Uszler, Marienne

1996-01-01

Provides a concise overview of the working conditions and challenges faced by independent music teachers (IMT). Most IMTs function in a number of capacities, as performer, teacher, and entrepreneur. Discusses changing trends in employment, including computer technology and the move for national certification. (MJP)

Marxism and Liberation Theology.

ERIC Educational Resources Information Center

Hudelson, Richard

1986-01-01

Provides a concise summary of the main features of Marxism and challenges the thesis of the Vatican's "Instruction on Certain Aspects of the Theology of Liberation" that any use of Marxist categories or analysis entails a wholesale acceptance of Marxist philosophy, with its atheistic implications. (Author/ABB)

Disposition and Mechanisms of Toxicities of Metals and Metalloids

EPA Science Inventory

Dr. Hughes will provide a concise overview of general disposition (e.g., absorption) and mechanisms of toxicity of metal toxicity (e.g., direct interaction with functional groups of critical proteins, generation of reactive oxygen species, and alteration of cell signaling pathway...

Staphylococcus aureus

USDA-ARS?s Scientific Manuscript database

There is a need, in addition to the peer-reviewed research publications, for a concise monograph that provides a thoughtful synthesis of the genome sequencing data of key etiologic agents for food borne disease, with a focus on the novel, interesting, and potentially useful aspects of the genome se...

Quantum Optics in Phase Space

NASA Astrophysics Data System (ADS)

Schleich, Wolfgang P.

2001-04-01

Quantum Optics in Phase Space provides a concise introduction to the rapidly moving field of quantum optics from the point of view of phase space. Modern in style and didactically skillful, Quantum Optics in Phase Space prepares students for their own research by presenting detailed derivations, many illustrations and a large set of workable problems at the end of each chapter. Often, the theoretical treatments are accompanied by the corresponding experiments. An exhaustive list of references provides a guide to the literature. Quantum Optics in Phase Space also serves advanced researchers as a comprehensive reference book. Starting with an extensive review of the experiments that define quantum optics and a brief summary of the foundations of quantum mechanics the author Wolfgang P. Schleich illustrates the properties of quantum states with the help of the Wigner phase space distribution function. His description of waves ala WKB connects semi-classical phase space with the Berry phase. These semi-classical techniques provide deeper insight into the timely topics of wave packet dynamics, fractional revivals and the Talbot effect. Whereas the first half of the book deals with mechanical oscillators such as ions in a trap or atoms in a standing wave the second half addresses problems where the quantization of the radiation field is of importance. Such topics extensively discussed include optical interferometry, the atom-field interaction, quantum state preparation and measurement, entanglement, decoherence, the one-atom maser and atom optics in quantized light fields. Quantum Optics in Phase Space presents the subject of quantum optics as transparently as possible. Giving wide-ranging references, it enables students to study and solve problems with modern scientific literature. The result is a remarkably concise yet comprehensive and accessible text- and reference book - an inspiring source of information and insight for students, teachers and researchers alike.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kolda, Tamara Gibson

We propose two new multilinear operators for expressing the matrix compositions that are needed in the Tucker and PARAFAC (CANDECOMP) decompositions. The first operator, which we call the Tucker operator, is shorthand for performing an n-mode matrix multiplication for every mode of a given tensor and can be employed to concisely express the Tucker decomposition. The second operator, which we call the Kruskal operator, is shorthand for the sum of the outer-products of the columns of N matrices and allows a divorce from a matricized representation and a very concise expression of the PARAFAC decomposition. We explore the properties ofmore » the Tucker and Kruskal operators independently of the related decompositions. Additionally, we provide a review of the matrix and tensor operations that are frequently used in the context of tensor decompositions.« less

Microfiltration and Ultrafiltration Membranes for Drinking Water

EPA Science Inventory

This article provides a concise and abbreviated summary of AWWA Manual of Practice M53, Microfiltration and Ultrafiltration Membranes for Drinking Water, to serve as a quick point of reference. For convenience, the article’s organization matches that of M53, as follows: • wate...

Cloud Computing Explained

ERIC Educational Resources Information Center

Metz, Rosalyn

2010-01-01

While many talk about the cloud, few actually understand it. Three organizations' definitions come to the forefront when defining the cloud: Gartner, Forrester, and the National Institutes of Standards and Technology (NIST). Although both Gartner and Forrester provide definitions of cloud computing, the NIST definition is concise and uses…

Silvics of Missouri bottomland tree species

Treesearch

John Kabrick; Daniel Dey

2001-01-01

This issue of Notes For Forest Managers provides a concise summary of important silvical characteristics of Missouri's bottomland trees. It focuses on species adaptations to or tolerances of, environmental and site conditions. It is a compilation of information from seven different references cited in the text.

Training the Technical Editor.

ERIC Educational Resources Information Center

Cathcart, Margaret E.

The demand for skilled technical editors is growing as society places increasing emphasis on receiving accurate, concise, and complete technical data. Since many organizations do not have inhouse programs for training technical editors, a need exists to provide inexperienced people with basic editing skills. One organization has developed two…

Integrated Science Assessment (ISA) for Lead (Final Report, Jul 2013)

EPA Science Inventory

EPA announced the availability of the final report, Integrated Science Assessment (ISA) for Lead (Pb). This document represents a concise synthesis and evaluation of the most policy-relevant science and will ultimately provide the scientific bases for EPA’s decision regard...

Integrating Creativity into Online University Classes

ERIC Educational Resources Information Center

Muirhead, Brent

2007-01-01

In this article, the author provides a concise discussion on creativity, defining the term, sharing theoretical background information and offering insights into promoting creativity in online university classes. Emphasis will be placed on relevant ways to integrate creativity into instructional activities across the academic disciplines. He…

5 CFR 297.307 - Statement of disagreement.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Section 297.307 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PRIVACY... concise statement of disagreement. Such a statement should be filed with the appropriate system manager... system manager should provide a copy of the statement of disagreement to any individual or agency to whom...

5 CFR 297.307 - Statement of disagreement.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Section 297.307 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PRIVACY... concise statement of disagreement. Such a statement should be filed with the appropriate system manager... system manager should provide a copy of the statement of disagreement to any individual or agency to whom...

Constructive Management of Conflict in Groups.

ERIC Educational Resources Information Center

Mitchell, Rex C.; Mitchell, Rie R.

1984-01-01

Provides a concise overview of important conflict management concepts and strategies for those working in group settings. Presents a brief conceptual basis for understanding conflict and group memebers' behavior when in conflict, followed by specific recommendations for managing and making use of conflict in groups. (JAC)

Types and Consequences of DNA Damage

EPA Science Inventory

This review provides a concise overview of the types of DNA damage and the molecular mechanisms by which a cell senses DNA damage, repairs the damage, converts the damage into a mutation, or dies as a consequence of unrepaired DNA damage. Such information is important in consid...

MARINE MAMMAL DISEASES: PATHOGENS AND PROCESSES

EPA Science Inventory

The purpose of this chapter is to provide a concise overview of the pathogens and processes that alter the health of marine mammals. Viral disease is the most common etiology of significant mortality events in marine mammals. Discussion of viral disease focuses on effects in the ...

China: Background Notes Series.

ERIC Educational Resources Information Center

Reams, Joanne Reppert

Concise background information on the People's Republic of China is provided. The publication begins with a profile of the country, outlining the people, geography, economy, and membership in international organizations. The bulk of the document then discusses in more detail China's people, geography, history, government, education, economy, and…

Solar Energy Information and Education Project. Final Report.

ERIC Educational Resources Information Center

Hensley, Michael

The New Mexico Solar Energy Institute (NMSEI) conducted a concentrated information and education program during 1985. This report summarizes NMSEI's Information and Education project activities. It provides detailed descriptions of project costs and concise recommendations for similar programs. Individual sections contain explanations of the scope…

A simple rule of direct reciprocity leads to the stable coexistence of cooperation and defection in the Prisoner's Dilemma game.

PubMed

Zheng, Xiu-Deng; Li, Cong; Yu, Jie-Ru; Wang, Shi-Chang; Fan, Song-Jia; Zhang, Bo-Yu; Tao, Yi

2017-05-07

The long-term coexistence of cooperation and defection is a common phenomenon in nature and human society. However, none of the theoretical models based on the Prisoner's Dilemma (PD) game can provide a concise theoretical model to explain what leads to the stable coexistence of cooperation and defection in the long-term even though some rules for promoting cooperation have been summarized (Nowak, 2006, Science 314, 1560-1563). Here, based on the concept of direct reciprocity, we develop an elementary model to show why stable coexistence of cooperation and defection in the PD game is possible. The basic idea behind our theoretical model is that all players in a PD game prefer a cooperator as an opponent, and our results show that considering strategies allowing opting out against defection provide a general and concise way of understanding the fundamental importance of direct reciprocity in driving the evolution of cooperation. Copyright © 2017 Elsevier Ltd. All rights reserved.

The Primary Care Behavioral Health (PCBH) Model: An Overview and Operational Definition.

PubMed

Reiter, Jeffrey T; Dobmeyer, Anne C; Hunter, Christopher L

2018-06-01

The Primary Care Behavioral Health (PCBH) model is a prominent approach to the integration of behavioral health services into primary care settings. Implementation of the PCBH model has grown over the past two decades, yet research and training efforts have been slowed by inconsistent terminology and lack of a concise, operationalized definition of the model and its key components. This article provides the first concise operationalized definition of the PCBH model, developed from examination of multiple published resources and consultation with nationally recognized PCBH model experts. The definition frames the model as a team-based approach to managing biopsychosocial issues that present in primary care, with the over-arching goal of improving primary care in general. The article provides a description of the key components and strategies used in the model, the rationale for those strategies, a brief comparison of this model to other integration approaches, a focused summary of PCBH model outcomes, and an overview of common challenges to implementing the model.

Acquired Aplastic Anemia in Children

PubMed Central

Hartung, Helge D.; Olson, Timothy S.; Bessler, Monica

2013-01-01

SYNOPSIS This article provides a practice-based and concise review of the etiology, diagnosis, and management of acquired aplastic anemia in children. Bone marrow transplantation, immunosuppressive therapy, and supportive care are discussed in detail. The aim is to provide the clinician with a better understanding of the disease and to offer guidelines for the management of children with this uncommon yet serious disorder. PMID:24237973

Moles: Tool-Assisted Environment Isolation with Closures

NASA Astrophysics Data System (ADS)

de Halleux, Jonathan; Tillmann, Nikolai

Isolating test cases from environment dependencies is often desirable, as it increases test reliability and reduces test execution time. However, code that calls non-virtual methods or consumes sealed classes is often impossible to test in isolation. Moles is a new lightweight framework which addresses this problem. For any .NET method, Moles allows test-code to provide alternative implementations, given as .NET delegates, for which C# provides very concise syntax while capturing local variables in a closure object. Using code instrumentation, the Moles framework will redirect calls to provided delegates instead of the original methods. The Moles framework is designed to work together with the dynamic symbolic execution tool Pex to enable automated test generation. In a case study, testing code programmed against the Microsoft SharePoint Foundation API, we achieved full code coverage while running tests in isolation without an actual SharePoint server. The Moles framework integrates with .NET and Visual Studio.

The Community College Story. Third Edition

ERIC Educational Resources Information Center

Vaughan, George B.

2006-01-01

This concise history of community colleges touches on major themes, including open access and equity, comprehensiveness, community-based philosophy, commitment to teaching, and lifelong learning. The third edition includes revised text as well as updated statistical information, time line, reading list, and Internet resources. In the more than a…

The Workaholism Syndrome: An Emerging Issue in the Psychological Literature

ERIC Educational Resources Information Center

Piotrowski, Chris; Vodanovich, Stephen J.

2008-01-01

The present paper provides a concise overview of the "workaholism syndrome." This includes a discussion of workaholism from an addiction perspective, it's overall components and consequences, and a conceptual framework. Suggestions are offered for effective strategies to confront and mediate the onerous impact of workaholism.

Diagnosis and Treatment of Eating Disorders.

ERIC Educational Resources Information Center

Neuman, Patricia; And Others

This paper was designed to provide professional counselors with a comprehensive but concise method of accurately evaluting, interviewing, and planning for treatment of eating disorder clients. The paper is organized in five sections. The first section, Diagnosis, compares, contrasts, and offers clear explanations of the diagnostic criteria for…

76 FR 43726 - Solicitation for a Cooperative Agreement: Developing a Method for Conducting an Internal...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-21

... domains, such as leadership, external collaboration, management and operations, sanctions, assessment and... concise and accessible format provides an opportunity for agency leadership and management to assess... Audience: The primary audience for this product is the leadership and management of correctional...

44 CFR 10.12 - Pre-implementation actions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... decision-making process. Because of the diversity of FEMA, it is not feasible to describe in this part the... shall provide further guidance, commensurate with their programs and organization, for integration of... the decision. Rather it is a concise document that sets forth the decision and describes the...

BIOLOGICAL EFFECTS AND DOSIMETRY OF STATIC AND ELF (EXTREMELY LOW FREQUENCY) ELECTROMAGNETIC FIELDS

EPA Science Inventory

The book offers a good introduction to the research field for students, as well as a valuable overall review for the experienced investigator. The six chapters on interactions provide concise descriptions of physical processes for natural and man-made environmental exposures and ...

A Brief History.

ERIC Educational Resources Information Center

Yalouris, Nicolaos

1996-01-01

Provides a brief but concise overview of the historical development of the Olympic Games in ancient Greece. Originally conceived as a one day, single-race event, the Games grew to the point where they represented an apotheosis of Greek culture. Discusses the role played by conflict within the city-states. (MJP)

Handbook of noise ratings

NASA Technical Reports Server (NTRS)

Pearsons, K. S.; Bennett, R. L.

1974-01-01

The handbook was compiled to provide information in a concise form, describing the multitude of noise rating schemes. It is hoped that by describing the noise rating methods in a single volume the user will have better access to the definitions, application and calculation procedures of the current noise rating methods.

Vocabulary Instruction: Research to Practice. Second Edition

ERIC Educational Resources Information Center

Kame'enui, Edward J., Ed.; Baumann, James F., Ed.

2012-01-01

This highly regarded work brings together prominent authorities on vocabulary teaching and learning to provide a comprehensive yet concise guide to effective instruction. The book showcases practical ways to teach specific vocabulary words and word-learning strategies and create engaging, word-rich classrooms. Instructional activities and games…

Integrated Science Assessment (ISA) of Ozone and Related Photochemical Oxidants (Final Report, Feb 2013)

EPA Science Inventory

EPA announced the availability of the final report, Integrated Science Assessment of Ozone and Related Photochemical Oxidants. This document represents a concise synthesis and evaluation of the most policy-relevant science and will ultimately provide the scientific bases f...

Try a Videotape for Communicating with District Patrons.

ERIC Educational Resources Information Center

DiazGrandox, Frederick

1991-01-01

A small Idaho school district gained public support for a school levy by producing and distributing a videotape of school activities and district needs. The videotape provided a clear, concise presentation of information while avoiding confrontations that often occur with other methods of communication. (Author/SV)

Real-Time Computer-Mediated Communication: Email and Instant Messaging Simulation

ERIC Educational Resources Information Center

Newman, Amy

2007-01-01

As computer-mediated communication becomes increasingly prevalent in the workplace, students need to apply effective writing principles to today's technologies. Email, in particular, requires interns and new hires to manage incoming messages, use an appropriate tone, and craft clear, concise messages. In addition, with instant messaging (IM)…

Monthly Financial Reporting: Keeping the Community Informed.

ERIC Educational Resources Information Center

Weeks, Richard H.

1998-01-01

Accurate, timely, and concise monthly financial reporting is achieved through mastering statistics. A Grafton, Massachusetts school business manager's monthly presentation to the school committee is a composite of all the statistics he has reviewed during the previous month. This presentation reports where and how funds have been spent and…

29 CFR 1404.5 - Listing on the roster, criteria for listing and removal, procedure for removal.

Code of Federal Regulations, 2011 CFR

2011-07-01

...) of this section are preferably demonstrated by the submission of five recent arbitration awards... MEDIATION AND CONCILIATION SERVICE ARBITRATION SERVICES Roster of Arbitrators; Admission and Retention... exhibits and can prepare clear and concise findings and awards within reasonable time limits. (iv) For...

78 FR 28749 - Private Land Mobile Radio Stations Below 800 MHz

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-16

... private land mobile radio (PLMR) licensing, including increasing the power limit for end-of-train devices, modifying trunking rules for PLMR stations below 800 MHz, and permitting digital transmission of station... provide clear and concise rules that facilitate new wireless technologies, devices and services, and are...

Women's Health USA, 2003.

ERIC Educational Resources Information Center

Health Resources and Services Administration (DHHS/PHS), Rockville, MD. Bureau of Maternal and Child Health and Resources Development.

This book provides a collection of current and historical data on some of the most pressing health challenges facing women, their families, and their communities. It is intended to be a concise reference for policymakers and program managers at the federal, state, and local levels. The book brings together the latest available data from various…

Russian HyperTutor: Designing Interactive Multimedia for the Macintosh.

ERIC Educational Resources Information Center

Mitrevski, George

1995-01-01

Describes an interactive, multimedia computer program designed to teach Russian grammar, and accompany a commercial textbook. Each of the 35 lessons integrates graphics, sound, and animation. A dictionary and extensive vocabulary exercises are also included. Tutorials provide simple but concise grammar explanations that the teacher can edit or…

Integrated Science Assessment (ISA) for Oxides of Nitrogen and Sulfur - Ecological Criteria (Final Report, Dec 2008)

EPA Science Inventory

EPA announced the availability of the final report, Integrated Science Assessment (ISA) for Oxides of Nitrogen and Sulfur - Ecological Criteria. This document represents a concise synthesis and evaluation of the most policy-relevant science and will ultimately provide the ...

Integrated Science Assessment for Oxides of Nitrogen – Health Criteria (Final Report, Jul 2008)

EPA Science Inventory

The Integrated Science Assessment (ISA) for Oxides of Nitrogen – Health Criteria document represents a concise synthesis and evaluation of the most policy-relevant science and will ultimately provide the scientific bases for EPA’s decision regarding whether the current standard f...

Preliminary analysis of an integrated logistics system for OSSA payloads. Volume 3: OSSA integrated logistics support planning document

NASA Technical Reports Server (NTRS)

Palguta, T.; Bradley, W.; Stockton, T.

1988-01-01

Guidance in preparing and updating an integrated logistics support plan (ILSP) is given. Clear, concise, and detailed instructions are provided on the preparation and content of an ILSP in order to ensure a quality document that reflects total program requirements.

Reading Motivation and Reading Engagement: Clarifying Commingled Conceptions

ERIC Educational Resources Information Center

Unrau, Norman J.; Quirk, Matthew

2014-01-01

The constructs of motivation for reading and reading engagement have frequently become blurred and ambiguous in both research and discussions of practice. To address this commingling of constructs, the authors provide a concise review of the literature on motivation for reading and reading engagement and illustrate the blurring of those concepts…

The Really Useful Elementary Science Book

ERIC Educational Resources Information Center

Bloom, Jeffrey W.

2010-01-01

Amongst the challenges that elementary teachers may often face as they introduce their students to science is the need to maintain a solid understanding of the many scientific concepts and details themselves. This indispensible resource, intended for pre- and in-service elementary school teachers, provides concise and comprehensible explanation of…

Population. Readings for Senior Secondary Social Studies. Updated 1989.

ERIC Educational Resources Information Center

Victoria International Development Education Association (British Columbia).

This document contains the information kit developed for the annual Model Summit Conferences for schools in the Victoria, British Columbia (Canada) and surrounding school districts. Materials germane to the conference topic were compiled and assembled for participants. The materials are of current interest, concise, simple and provide a balanced…

SPEAKEASY HELP documents

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fink, J.K.

1972-07-01

The HELP documents provide SPEAKEASY users with concise definitions of most of the words available in the current processors. In this report, the documents are given in a variety of formats to enable one to find specific information quickly. The bulk of this report consists of computer read-out of the HELP library via SPEAKEASY.

Glossary of software engineering laboratory terms

NASA Technical Reports Server (NTRS)

1982-01-01

A glossary of terms used in the Software Engineering Laboratory (SEL) is presented. The terms are defined within the context of the software development environment for flight dynamics at Goddard Space Flight Center. A concise reference for clarifying and understanding the language employed in SEL documents and data collection forms is provided.

Between Pandemonium and Order: Assessing International Organizations and Multiethnic Societies.

ERIC Educational Resources Information Center

Lauren, Paul Gordon

1996-01-01

Provides a concise and fascinating overview of the historical development of international efforts responding to incidents of atrocities and oppression. Traces this humanitarian impulse from the mid-19th century, through the League of Nations, to the current United Nations. Considers the limitations and potentialities of current endeavors. (MJP)

RTI and Other Approaches to SLD Identification under the IDEA: A Legal Update

ERIC Educational Resources Information Center

Zirkel, Perry A.

2017-01-01

This article provides a concise and objective synthesis of the federal legislation, regulations, and agency policy interpretations; state laws; and case law, including hearing officer and complaint investigation decisions, concerning specific learning disability (SLD) identification since the 2006 IDEA regulations. The results reveal wide latitude…

Cis and Trans Isomers of Cycloalkenes

ERIC Educational Resources Information Center

Barrows, Susan E.; Eberlein, Thomas H.

2005-01-01

A study investigates the strain in medium-sized cycloalkenes and the geometric and electronic distortions through which alkenes can relieve that strain. Literature data is summarized and results are presented with the aim of providing a concise reference for those interested in addressing the topic in an introductory organic chemistry curriculum.

Understanding Program Monitoring: The Relationships among Outcomes, Indicators, Measures, and Targets. REL 2014-011

ERIC Educational Resources Information Center

Malone, Nolan; Mark, Lauren; Narayan, Krishna

2014-01-01

This guide offers educators, program managers, administrators, and researchers a resource for building capacity for monitoring program outcomes. It provides concise definitions of program monitoring components and a framework for assessing program progress. Examples demonstrate the relationships among program components: outcomes, indicators,…

Understanding the Civil Justice System.

ERIC Educational Resources Information Center

Hirshon, Robert E.; Bolduan, Linda M.

1997-01-01

Provides a concise and informative overview of the civil justice system. Examines various components and issues including the federal and state court systems, differences between civil and criminal law, background in common law, types of civil law, civil procedure, and the effect and implementation of civil law in everyday life. (MJP)

Aflatoxin control measures: A basis for improved health in developing countries

USDA-ARS?s Scientific Manuscript database

The goal of this IARC Working Group Report is to produce a document, based on expertly evaluated scientific evidence, which provides a set of clear, concise and focused messages to inform policymakers, international organizations and funders in their decision-making with regards to appropriate aflat...

Integrated Science Assessment (ISA) for Sulfur Oxides – Health Criteria (Final Report, Sep 2008)

EPA Science Inventory

EPA announced the availability of the final report, Integrated Science Assessment (ISA) for Sulfur Oxides – Health Criteria final assessment. This report represents a concise synthesis and evaluation of the most policy-relevant science and will ultimately provide the scien...

Cuban Geography in Higher Education: Survival in the "Special Period."

ERIC Educational Resources Information Center

Miller, Mark M.; And Others

1996-01-01

Provides a concise and interesting overview of the state of higher education in Cuba, specifically focusing on geography. The interests, methodologies, and programs of Cuban geographers are similar to other countries, albeit at a truncated level due to the United States embargo. Discusses international educational exchange efforts. (MJP)

The Law on Gifted Education: Revised Edition

ERIC Educational Resources Information Center

Zirkel, Perry A.

2005-01-01

This monograph provides a comprehensive, concise, and current overview of the law-- specifically, legislation, regulations, and published court/administrative decisions--relating to gifted education for K-12 students. For students whose legal rights are based solely on their gifted status, the law largely boils down to (a) varying state statutes…

Reporting School Violence. Legal Series Bulletin.

ERIC Educational Resources Information Center

Department of Justice, Washington, DC. Office of Justice Programs.

Violence and crime in schools affect students and their families, school employees and administrators, law enforcement and criminal justice officials, policymakers, and communities. Enactment of strong, concise school violence reporting laws is a crucial first step on the road to making schools safe and violence free. This bulletin provides an…

Granulocyte colony-stimulating factor in the treatment of acute radiation syndrome: a concise review.

PubMed

Hofer, Michal; Pospíšil, Milan; Komůrková, Denisa; Hoferová, Zuzana

2014-04-16

This article concisely summarizes data on the action of one of the principal and best known growth factors, the granulocyte colony-stimulating factor (G-CSF), in a mammalian organism exposed to radiation doses inducing acute radiation syndrome. Highlighted are the topics of its real or anticipated use in radiation accident victims, the timing of its administration, the possibilities of combining G-CSF with other drugs, the ability of other agents to stimulate endogenous G-CSF production, as well as of the capability of this growth factor to ameliorate not only the bone marrow radiation syndrome but also the gastrointestinal radiation syndrome. G-CSF is one of the pivotal drugs in the treatment of radiation accident victims and its employment in this indication can be expected to remain or even grow in the future.

Development of a Disaster Information Visualization Dashboard: A Case Study of Three Typhoons in Taiwan in 2016

NASA Astrophysics Data System (ADS)

Su, Wen-Ray; Tsai, Yuan-Fan; Huang, Kuei-Chin; Hsieh, Ching-En

2017-04-01

To facilitate disaster response and enhance the effectiveness of disaster prevention and relief, people and emergency response personnel should be able to rapidly acquire and understand information when disasters occur. However, in existing disaster platforms information is typically presented in text tables, static charts, and maps with points. These formats do not make it easy for users to understand the overall situation. Therefore, this study converts data into human-readable charts by using data visualization techniques, and builds a disaster information dashboard that is concise, attractive and flexible. This information dashboard integrates temporally and spatially correlated data, disaster statistics according to category and county, lists of disasters, and any other relevant information. The graphs are animated and interactive. The dashboard allows users to filter the data according to their needs and thus to assimilate the information more rapidly. In this study, we applied the information dashboard to the analysis of landslides during three typhoon events in 2016: Typhoon Nepartak, Typhoon Meranti and Typhoon Megi. According to the statistical results in the dashboard, the order of frequency of the disaster categories in all three events combined was rock fall, roadbed loss, slope slump, road blockage and debris flow. Disasters occurred mainly in the areas that received the most rainfall. Typhoons Nepartak and Meranti mainly affected Taitung, and Typhoon Megi mainly affected Kaohsiung. The towns Xiulin, Fengbin, Fenglin and Guangfu in Hualian County were all issued with debris flow warnings in all three typhoon events. The disaster information dashboard developed in this study allows the user to rapidly assess the overall disaster situation. It clearly and concisely reveals interactions between time, space and disaster type, and also provides comprehensive details about the disaster. The dashboard provides a foundation for future disaster visualization, since it can combine and present real-time information of various types; as such it will strengthen decision making in disaster prevention management.

What Does it Take to Be a True Muslim? Implications for Efforts to Counter al-Qa’ida’s Violent Extremist Narrative

DTIC Science & Technology

2014-01-01

Haddad, “Al-Albani – Chief Innovator of Our Time,” As-Sunnah Foundation of America, n.d., http://sunnah.org/ wordpress /2008/07/18/al-albani-chief...sunnah.org/ wordpress /2008/07/18/al-albani-chief-innovator-in- our-time/ . Haddad, Gibril Fouad. Albani & His Friends: A Concise Guide to the Salafi

Occupational Choice Strategy: A Small Group Vocational Counseling Program. Trainer's Guide.

ERIC Educational Resources Information Center

Schriner, Kay Fletcher; Roessler, Richard T.

Intended for use by rehabilitation professionals counseling small groups of disabled people, the Occupational Choice Strategy (OCS) was designed to be responsive to both the needs and desires of the disabled and the cost and time constraints faced by rehabilitation counselors. OCS incorporates: (1) concise occupational information easily accessed…

21 CFR 25.43 - Records of decision.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Records of decision. 25.43 Section 25.43 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ENVIRONMENTAL IMPACT... environmental impact statements, at the time of its decision, the agency shall prepare a concise public record...

Emphasizing the "Literacy" in "Scientific Literacy": A Concise Blueprint for Integrating Writing into Biology Classes

ERIC Educational Resources Information Center

Yule, Jeffrey V.; Wolf, William C.; Young, Nolan L.

2010-01-01

Effectively integrating writing into biology classes gives students the opportunity to develop a better understanding of and engagement with course content. Yet many instructors remain reluctant to emphasize writing. Some are concerned about the time commitment writing assessment requires. Others shy away from emphasizing writing in their classes…

Efforts to update firefighter safety zone guidelines

Treesearch

Bret Butler

2009-01-01

One of the most critical decisions made on wildland fires is the identification of suitable safety zones for firefighters during daily fire management operations. To be effective (timely, repeatable, and accurate), these decisions rely on good training and judgment, but also on clear, concise guidelines. This article is a summary of safety zone guidelines and the...

Cosmology of Universe Particles and Beyond

NASA Astrophysics Data System (ADS)

Xu, Wei

2016-06-01

For the first time in history, all properties of cosmology particles are uncovered and described concisely and systematically, known as the elementary particles in contemporary physics.Aligning with the synthesis of the virtual and physical worlds in a hierarchical taxonomy of the universe, this theory refines the topology framework of cosmology, and presents a new perspective of the Yin Yang natural laws that, through the processes of creation and reproduction, the fundamental elements generate an infinite series of circular objects and a Yin Yang duality of dynamic fields that are sequenced and transformed states of matter between the virtual and physical worlds.Once virtual objects are transformed, they embody various enclaves of energy states, known as dark energy, quarks, leptons, bosons, protons, and neutrons, characterized by their incentive oscillations of timestate variables in a duality of virtual realities: energy and time, spin and charge, mass and space, symmetry and antisymmetry.As a consequence, it derives the fully-scaled quantum properties of physical particles in accordance with numerous historical experiments, and has overcome the limitations of uncertainty principle and the Standard Model, towards concisely exploring physical nature and beyond...

Educational Leadership in the Spiritual Way: "Whatever Will Be, Will Be"

ERIC Educational Resources Information Center

Thom, Douglas J.; Ma, Qi; Ho, Kwok Keung

2005-01-01

Background: The article provides a broad, concise overview with the intent to provoke scholarly argument and debate on an illusive, yet majestic, theme. Purpose: In this article, the authors make the case for educational leaders who are spiritual. Argument: The contemporary postmodern world society is very cosmopolitan and pluralistic. The…

From Afar to Zulu: A Dictionary of African Cultures.

ERIC Educational Resources Information Center

Haskins, Jim; Biondi, Joann

This resource provides information on over 30 of Africa's most populous and well-known ethnic groups. The text concisely describes the history, traditions, environment, social structure, religion, and daily lifestyles of these diverse cultures. Each entry opens with a map outlining the area populated by the group and a list of key data regarding…

Nonlinearity: The History and Philosophy of the Science

ERIC Educational Resources Information Center

Burke, Kenneth M.

2009-01-01

This article provides for a concise history of nonlinearity from the context of the changing assumptions in science throughout the turn of the twentieth century. Concerned with the development of an ethics of technology in higher education, it establishes a background for ongoing research on quantitative methods in the social sciences. The history…

Fire Use Planning

Treesearch

Tom Leuschen; Dale Wade; Paula Seamon

2001-01-01

The success of a fire use program is in large part dependent on a solid foundation set in clear and concise planning. The planning process results in specific goals and measurable objectives for fire application, provides a means of setting priorities, and establishes a mechanism for evaluating and refining the process to meet the desired future condition. It is an...

Psychosemiotics and Libraries: Identifying Signways in Library Informational Guides, Games, and Tutorials

ERIC Educational Resources Information Center

Laster, Barbara; Blummer, Barbara; Kenton, Jeffrey M.

2010-01-01

Tutorials and digital learning objects provide librarians a quick, concise mechanism for delivering information and training on a wide range of library topics. The semiotic theory promoted by Charles Sanders Peirce (Wiener, 1958) and Howard Smith (2005) contains implications for enhancing the effectiveness of library tutorials through the…

California Curriculum Frameworks: A Handbook for Production, Implementation, and Evaluation Activities.

ERIC Educational Resources Information Center

California State Dept. of Education, Sacramento.

This booklet describes the characteristics and role of curriculum frameworks and describes how they can be used in developing educational programs. It is designed as a guide for writers of frameworks, for educators who are responsible for implementing frameworks, or for evaluators of educational programs. It provides a concise description of the…

English Language Learners in Canadian Schools: Emerging Directions for School-Based Policies

ERIC Educational Resources Information Center

Cummins, Jim; Mirza, Rania; Stille, Saskia

2012-01-01

This article attempts to provide ESL teachers, school administrators, and policymakers with a concise overview of what matters in promoting academic success among learners of English in Canadian schools. We review research focused on bilingual and biliteracy development, the nature of academic language, and the roles of societal power relations…

Preliminary analysis of an integrated logistics system for OSSA payloads. Volume 1: Executive summary

NASA Technical Reports Server (NTRS)

Palguta, T.; Bradley, W.; Stockton, T.

1988-01-01

The purpose is to describe the logistics study background and approach to providing estimates of of logistics support requirements for Office of Space Science and Applications' payloads in the Space Station era. A concise summary is given of the study results. Future logistics support analysis tasks are identified.

Questions about Careers in Oceanography.

ERIC Educational Resources Information Center

Anderson, Aubrey L.

Knowing the relationship of the ocean to man, the weather and climate, availability of resources from the ocean, use of the ocean in transporation, waste disposal, and defense, and developing an understanding of the impact on the oceans of human activity are all goals of oceanographers. The goal of this brochure is to provide concise informative…

Lewis Online Travel System: Preparer's/Traveler's Manual, Release 1.0

NASA Technical Reports Server (NTRS)

Seese, Michael

1992-01-01

The Lewis Online Travel System (LOTS) is a menu-driven interactive application that automates nearly all of the functions associated with government travel. The purpose of this manual is to provide LOTS users with concise instructions for using the computerized application. As such, it will not go into the details of travel regulations.

Computers: Their History and How They Work.

ERIC Educational Resources Information Center

Rusch, Richard B.

Electronic data processing has become commonplace. To aid the layman to understand his relationship to his new technology, this book provides a concise account of the role of the computer, how it came into being, and what physical equipment is included in today's advanced computer systems. The book discusses machine languages and codes, the binary…

Serbian: The Serbian Language in Education in Hungary. Regional Dossiers Series

ERIC Educational Resources Information Center

Paulik, Anton, Comp.; Solymosi, Judit, Comp.

2014-01-01

This regional dossier aims at providing a concise description of and basic statistics on minority language education in a specific region of Europe--the territory of Magyarország (Hungary). Aspects that are addressed include features of the education system, recent educational policies, main actors, legal arrangements, and support structures, as…

Employee Benefits: New Directions. Corporate Support for Employees with Dependents.

ERIC Educational Resources Information Center

Arkansas Advocates for Children and Families, Little Rock.

Written for employers, this pamphlet provides a concise picture of many aspects of employer supported child care. The influx of working parents into the workplace--especially mothers with young children--has increased stress and pressure for both employees and employers. This, in turn, has increased the mutual dependence between businesses and the…

75 FR 33839 - Biweekly Notice; Applications and Amendments to Facility Operating Licenses Involving No...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-15

... requestor/petitioner shall provide a brief explanation of the bases for the contention and a concise... report and bases to TS), since these are not affected by changes to the surveillance frequencies... bases to TS), since these are not affected by changes to the surveillance frequencies. Similarly, there...

76 FR 18801 - Biweekly Notice; Applications and Amendments to Facility Operating Licenses Involving No...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-05

.../petitioner shall provide a brief explanation of the bases for the contention and a concise statement of the.... The fuel rod design bases are established to satisfy the general and specific safety criteria..., ``Primary Containment Isolation Instrumentation,'' by deleting channel check Surveillance Requirement 3.3.6...

Procedures for Conducting Installation Compatible Use Zone (ICUZ) studies

DTIC Science & Technology

1988-08-01

Yes ( Penguin Books, New York, 1986). This book is a national bestseller on negotiation. It provides a concise, step-by-step, proven strategy for...AL ftA TE trate your proposal: Basic Principles of this CP TECHNIQUE - You may be able to transport some of the It’s not infrequent that public

"Quod Erat Demonstrandum": Understanding and Explaining Equations in Physics Teacher Education

ERIC Educational Resources Information Center

Karam, Ricardo; Krey, Olaf

2015-01-01

In physics education, equations are commonly seen as calculation tools to solve problems or as concise descriptions of experimental regularities. In physical science, however, equations often play a much more important role associated with the formulation of theories to provide explanations for physical phenomena. In order to overcome this…

Engaging the Online Learner: Activities and Resources for Creative Instruction. Updated Edition

ERIC Educational Resources Information Center

Conrad, Rita-Marie; Donaldson, J. Ana

2011-01-01

This is a revision of the first title in Jossey-Bass' Online Teaching & Learning series. This series helps higher education professionals improve the practice of online teaching and learning by providing concise, practical resources focused on particular areas or issues they might confront in this new learning environment. This revision includes…

12 CFR 792.59 - Appeal of initial determination.

Code of Federal Regulations, 2010 CFR

2010-01-01

... General Counsel shall either advise the individual of a decision to amend or correct the record, or advise... accounting made as required by the Privacy Act of 1974 or any other accounting previously made, of the... concise statement of the reasons for not making the requested amendment may also be provided if deemed...

76 FR 68225 - License Renewal Application for Purdue University

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-03

... each contention, the petitioner must provide a specific statement of the issue of law or fact to be... response to the application. The petition must also include a concise statement of the alleged facts or... exists with the applicant on a material issue of law or fact, including references to specific portions...

Updating Board Bylaws: A Guide for Colleges and Universities

ERIC Educational Resources Information Center

O'Neil, Robert M.

2013-01-01

"Updating Board Bylaws: A Guide for Colleges and Universities" represents the latest thinking on good governance in higher education by providing a concise deconstruction of the essential clauses in college, university, and system bylaws. Written by Robert O'Neil, former professor of law and president of the University of Wisconsin System and the…

Friulian: The Friulian Language in Education in Italy. Regional Dossiers Series

ERIC Educational Resources Information Center

Petris, Cinzia, Comp.

2014-01-01

This regional dossier aims to provide a concise, description and basic statistics about minority language education in a specific region of Europe. Aspects that are addressed include features of the education system, recent educational policies, main actors, legal arrangements, and support structures, as well as quantitative aspects, such as the…

Catalan: The Catalan Language in Education in Spain, 2nd Edition. Regional Dossiers Series

ERIC Educational Resources Information Center

Areny, Maria, Comp.; Mayans, Pere, Comp.; Forniès, David, Comp.

2013-01-01

Regional dossiers aim at providing a concise description and basic statistics about minority language education in a specific region of Europe. Aspects that are addressed include features of the education system, recent educational policies, main actors, legal arrangements, and support structures, as well as quantitative aspects, such as the…

Renewables-Friendly Grid Development Strategies. Experience in the United States, Potential Lessons for China

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hurlbut, David; Zhou, Ella; Porter, Kevin

2015-10-01

This report aims to help China's reform effort by providing a concise summary of experience in the United States with "renewables-friendly"" grid management, focusing on experiences that might be applicable to China. It focuses on utility-scale renewables and sets aside issues related to distributed generation.

Foundations of Cognitive Theory: A Concise Review.

ERIC Educational Resources Information Center

Grider, Clint

Cognitive-learning theories hold a unique place in history: they explore the depths of the mind from the perspective of process. This paper discusses the history of cognitive-learning theories and how they grew to shape the way one perceives, organizes, stores, and retrieves information. The paper, after providing a definition and synopsis of…

Concise Review: Mesenchymal Stromal Cell‐Based Approaches for the Treatment of Acute Respiratory Distress and Sepsis Syndromes

PubMed Central

Soeder, Yorick; Dahlke, Marc H.

2017-01-01

Abstract Despite extensive research on candidate pharmacological treatments and a significant and increasing prevalence, sepsis syndrome, and acute respiratory distress syndrome (ARDS) remain areas of unmet clinical need. Preclinical studies examining mesenchymal stromal cell (MSCs) based‐therapies have provided compelling evidence of potential benefit; however, the precise mechanism by which MSCs exert a therapeutic influence, and whether MSC application is efficacious in humans, remains unknown. Detailed evaluation of the limited number of human trials so far completed is further hampered as a result of variations in trial design and biomarker selection. This review provides a concise summary of current preclinical and clinical knowledge of MSCs as a cell therapy for sepsis syndrome and ARDS. The challenges of modeling such heterogeneous and rapidly progressive disease states are considered and we discuss how lessons from previous studies of pharmacological treatments for sepsis syndrome and ARDS might be used to inform and refine the design of the next generation of MSC clinical trials. Stem Cells Translational Medicine 2017;6:1141–1151 PMID:28186706

Nature: a new paradigm for well-being and ergonomics.

PubMed

Richardson, Miles; Maspero, Marta; Golightly, David; Sheffield, David; Staples, Vicki; Lumber, Ryan

2017-02-01

Nature is presented as a new paradigm for ergonomics. As a discipline concerned with well-being, the importance of natural environments for wellness should be part of ergonomics knowledge and practice. This position is supported by providing a concise summary of the evidence of the value of the natural environment to well-being. Further, an emerging body of research has found relationships between well-being and a connection to nature, a concept that reveals the integrative character of human experience which can inform wider practice and epistemology in ergonomics. Practitioners are encouraged to bring nature into the workplace, so that ergonomics keeps pace with the move to nature-based solutions, but also as a necessity in the current ecological and social context. Practitioner Summary: Nature-based solutions are coming to the fore to address societal challenges such as well-being. As ergonomics is concerned with well-being, there is a need for a paradigm shift in the discipline. This position is supported by providing a concise summary of the evidence of the value of the natural environment to well-being.

Pathogenesis of autism: a patchwork of genetic causes

PubMed Central

Grigorenko, Elena L

2009-01-01

Autism spectrum disorders (ASDs) are relatively infrequent but are devastating developmental conditions characterized by marked deficiencies in social, communicative and other behavioral domains. It has been known for a substantial period of time that these disorders are genetic in nature. However, elucidating the specific mechanisms of these disorders has been difficult. A major reason for such difficulty is the recognized genetic heterogeneity of ASDs. Specifically, many genetic mechanisms related to structural variations in the genome have been reported as possible genetic causes of these disorders. This review briefly exemplifies these genetic mechanisms, presents a concise overview of the evidence for the genetic basis of ASDs and provides an appraisal of the specific structural genetic variants thought to contribute to the pathogenesis of these complex disorders. PMID:19953194

10 CFR 75.34 - Inventory change reports.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Transactions Reports (Inventory Change Reports), when appropriate, must be accompanied by Concise Notes... Commission, Division of Fuel Cycle Safety and Safeguards, Washington, DC 20555-0001. This Concise Note is... operational program for the facility, including particularly, but not exclusively, the schedule for taking...

10 CFR 75.34 - Inventory change reports.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Transactions Reports (Inventory Change Reports), when appropriate, must be accompanied by Concise Notes... Commission, Division of Fuel Cycle Safety and Safeguards, Washington, DC 20555-0001. This Concise Note is... operational program for the facility, including particularly, but not exclusively, the schedule for taking...

10 CFR 75.34 - Inventory change reports.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Transactions Reports (Inventory Change Reports), when appropriate, must be accompanied by Concise Notes... Commission, Division of Fuel Cycle Safety and Safeguards, Washington, DC 20555-0001. This Concise Note is... operational program for the facility, including particularly, but not exclusively, the schedule for taking...

10 CFR 75.34 - Inventory change reports.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Transactions Reports (Inventory Change Reports), when appropriate, must be accompanied by Concise Notes... Commission, Division of Fuel Cycle Safety and Safeguards, Washington, DC 20555-0001. This Concise Note is... operational program for the facility, including particularly, but not exclusively, the schedule for taking...

A concise synthesis of optically active solanacol, the germination stimulant for seeds of root parasitic weeds.

PubMed

Kumagai, Hiroshi; Fujiwara, Mami; Kuse, Masaki; Takikawa, Hirosato

2015-01-01

Solanacol, isolated from tobacco (Nicotiana tabacum L.), is a germination stimulant for seeds of root parasitic weeds. A concise synthesis of optically active solanacol has been achieved by employing enzymatic resolution as a key step.

Assessment and management of alcohol dependence and withdrawal in the acute hospital: concise guidance.

PubMed

Stewart, Stephen; Swain, Sharon

2012-06-01

Alcohol dependence is common among patients attending acute hospitals. It can be the major reason for attendance or a significant cofactor. Assessment of these patients in the acute setting can be challenging owing to the multidisciplinary approach required. Doctors in acute hospitals are often inexperienced in managing dependence, a mental health problem. They might focus on the physical harms or the withdrawal, a consequence of the dependence. For this reason, assessment of dependence and prevention and management of acute alcohol withdrawal are often suboptimal. There is little existing guidance on how to manage this patient population, especially in non-specialist settings. With recently published National Institute for Health and Clinical Excellence (NICE) guidance on the management of dependence and withdrawal, now is the perfect time to produce concise guidelines in the hope that a more succinct suite of guidance can reach a larger audience.

Design and Fabrication of Full Wheatstone-Bridge-Based Angular GMR Sensors.

PubMed

Yan, Shaohua; Cao, Zhiqiang; Guo, Zongxia; Zheng, Zhenyi; Cao, Anni; Qi, Yue; Leng, Qunwen; Zhao, Weisheng

2018-06-05

Since the discovery of the giant magnetoresistive (GMR) effect, GMR sensors have gained much attention in last decades due to their high sensitivity, small size, and low cost. The full Wheatstone-bridge-based GMR sensor is most useful in terms of the application point of view. However, its manufacturing process is usually complex. In this paper, we present an efficient and concise approach to fabricate a full Wheatstone-bridge-based angular GMR sensor by depositing one GMR film stack, utilizing simple patterned processes, and a concise post-annealing procedure based on a special layout. The angular GMR sensor is of good linear performance and achieves a sensitivity of 0.112 mV/V/Oe at the annealing temperature of 260 °C in the magnetic field range from -50 to +50 Oe. This work provides a design and method for GMR-sensor manufacturing that is easy for implementation and suitable for mass production.

Targeted nanosystems: Advances in targeted dendrimers for cancer therapy.

PubMed

Yang, Hu

2016-02-01

Dendrimers possess discrete highly compact nanostructures constituted of successive branched layers. Soon after the inception of dendrimers, recognition of their tunable structures and biologically favorable properties provoked a great enthusiasm in delving deeply into the utility of dendrimers for biomedical and pharmaceutical applications. One of the most important nanotechnology applications is the development of nanomedicines for targeted cancer therapies. Tremendous success in targeted therapies has been achieved with the use of dendrimer-based nanomedicines. This article provides a concise review on latest advances in the utility of dendrimers in immunotherapies and hormone therapies. Much basic and clinical research has been done since the invention of dendrimers, which are highly branched nano-sized molecules with the ability to act as carriers in nanomedicine. In this concise review article, the authors highlighted the current use of dendrimers in immunotherapies and hormone therapies in the fight against cancers. Copyright © 2015 Elsevier Inc. All rights reserved.

Intelligent alarming

NASA Technical Reports Server (NTRS)

Braden, W. B.

1992-01-01

This talk discusses the importance of providing a process operator with concise information about a process fault including a root cause diagnosis of the problem, a suggested best action for correcting the fault, and prioritization of the problem set. A decision tree approach is used to illustrate one type of approach for determining the root cause of a problem. Fault detection in several different types of scenarios is addressed, including pump malfunctions and pipeline leaks. The talk stresses the need for a good data rectification strategy and good process models along with a method for presenting the findings to the process operator in a focused and understandable way. A real time expert system is discussed as an effective tool to help provide operators with this type of information. The use of expert systems in the analysis of actual versus predicted results from neural networks and other types of process models is discussed.

Notification of real-time clinical alerts generated by pharmacy expert systems.

PubMed Central

Miller, J. E.; Reichley, R. M.; McNamee, L. A.; Steib, S. A.; Bailey, T. C.

1999-01-01

We developed and implemented a strategy for notifying clinical pharmacists of alerts generated in real-time by two pharmacy expert systems: one for drug dosing and the other for adverse drug event prevention. Display pagers were selected as the preferred notification method and a concise, yet readable, format for displaying alert data was developed. This combination of real-time alert generation and notification via display pagers was shown to be efficient and effective in a 30-day trial. PMID:10566374

Personality, Organizational Orientations and Self-Reported Learning Outcomes

ERIC Educational Resources Information Center

Bamber, David; Castka, Pavel

2006-01-01

Purpose: To identify competencies connecting personality, organizational orientations and self-reported learning outcomes (as measured by concise Likert-type scales), for individuals who are learning for their organizations. Design/methodology/approach: Five concise factor scales were constructed to represent aspects of personality. Three further…

A General, Concise Strategy that Enables Collective Total Syntheses of over 50 Protoberberine and Five Aporhoeadane Alkaloids within Four to Eight Steps.

PubMed

Zhou, Shiqiang; Tong, Rongbiao

2016-05-17

A concise, catalytic, and general strategy that allowed efficient total syntheses of 22 natural 13-methylprotoberberines within four steps for each molecule is reported. This synthesis represents the most efficient and shortest route to date, featuring three catalytic processes: CuI-catalyzed redox-A(3) reaction, Pd-catalyzed reductive carbocyclization, and PtO2 -catalyzed hydrogenation. Importantly, this new strategy to the tetracyclic framework has also been applied to the collective concise syntheses of >30 natural protoberberines (without 13-methyl group) and five aporhoeadane alkaloids. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

The anatomy and art of writing a successful grant application: a practical step-by-step approach.

PubMed

Gholipour, Ali; Lee, Edward Y; Warfield, Simon K

2014-12-01

Writing a compelling grant application is a skill that is crucial to conducting high-quality and high-impact scientific research. A successful grant proposal provides the resources necessary to foster activity in an important area of investigation. A concise and practical overview of the anatomy and art of grant writing is provided in this article, along with citations to resources that are particularly useful for junior investigators.

Identifying Core Profiles in Attitudes toward School Violence

ERIC Educational Resources Information Center

Frisby, Craig L.; Kim, Se-Kang; Wolfmeyer, Mary Anne

2005-01-01

Focus group methods for studying opinions and perceptions of school violence are effective for understanding differences among individuals, but cannot report these differences in a concise manner. Traditional quantitative methods for analyzing data from school violence perception surveys allow for the concise reporting of data, but cannot…

New Insights into the Fractional Order Diffusion Equation Using Entropy and Kurtosis.

PubMed

Ingo, Carson; Magin, Richard L; Parrish, Todd B

2014-11-01

Fractional order derivative operators offer a concise description to model multi-scale, heterogeneous and non-local systems. Specifically, in magnetic resonance imaging, there has been recent work to apply fractional order derivatives to model the non-Gaussian diffusion signal, which is ubiquitous in the movement of water protons within biological tissue. To provide a new perspective for establishing the utility of fractional order models, we apply entropy for the case of anomalous diffusion governed by a fractional order diffusion equation generalized in space and in time. This fractional order representation, in the form of the Mittag-Leffler function, gives an entropy minimum for the integer case of Gaussian diffusion and greater values of spectral entropy for non-integer values of the space and time derivatives. Furthermore, we consider kurtosis, defined as the normalized fourth moment, as another probabilistic description of the fractional time derivative. Finally, we demonstrate the implementation of anomalous diffusion, entropy and kurtosis measurements in diffusion weighted magnetic resonance imaging in the brain of a chronic ischemic stroke patient.

Rainfall-runoff response informed by exact solutions of Boussinesq equation on hillslopes

NASA Astrophysics Data System (ADS)

Bartlett, M. S., Jr.; Porporato, A. M.

2017-12-01

The Boussinesq equation offers a powerful approach forunderstanding the flow dynamics of unconfined aquifers. Though this nonlinear equation allows for concise representation of both soil and geomorphological controls on groundwater flow, it has only been solved exactly for a limited number of initial and boundary conditions. These solutions do not include source/sink terms (evapotranspiration, recharge, and seepage to bedrock) and are typically limited to horizontal aquifers. Here we present a class of exact solutions that are general to sloping aquifers and a time varying source/sink term. By incorporating the source/sink term, they may describe aquifers with both time varying recharge over seasonal or weekly time scales, as well as a loss of water from seepage to the bedrock interface, which is a common feature in hillslopes. These new solutions shed light on the hysteretic relationship between streamflow and groundwater and the behavior of the hydrograph recession curves, thus providing a robust basis for deriving a runoff curves for the partition of rainfall into infiltration and runoff.

NRC/AMRMC Resident Research Associateship Program

DTIC Science & Technology

2013-04-01

Intravital Microscopy was successfully employed for investigating EG shedding in hemorrhagic shock/resuscitation for the very first time; Contract... Intravital microscopy integrated with systemic hemodynamics evaluations may be essential and more accurate tools to identify changes and study...findings in concise form, utilizing key concepts/words. 1) Intravital Microscopy was successfully employed for investigating EG shedding in hemorrhagic

A Sample Practical Report to Facilitate Writing in the Scientific Style

ERIC Educational Resources Information Center

Corradi, Hazel Ruth

2012-01-01

The ability to write concise and accurate scientific reports is highly valued in university level science. From reflection on marking student final year reports, it was apparent that many students have had insufficient practice at writing complete "scientific paper" style reports by that time, although some do it very well. This is a previously…

A Useful Expression for Relativistic Energy Conservation of a Point Mass in an Isotropic Static Gravitational Field

ERIC Educational Resources Information Center

Augousti, A. T.; Radosz, A.; Ostasiewicz, K.

2011-01-01

By using the symmetry and time-independence properties of Schwarzschild spacetime it is demonstrated that an energy conservation law may be expressed in terms of local velocity. From this form three important results may be derived very concisely. This highlights analogies and differences between relativistic and classical approaches to mechanics…

Manx Gaelic: The Manx Gaelic Language in Education in the Isle of Man. Regional Dossiers Series

ERIC Educational Resources Information Center

McArdle, Fiona, Comp.; Teare, Robert, Comp.

2016-01-01

This regional dossier aims at providing a concise description of and basic statistics on minority language education in a specific region of Europe--the Isle of Man. Aspects that are addressed include features of the education system, recent educational policies, main actors, legal arrangements, and support structures, as well as quantitative…

Chemical ecology and management of bark beetles in western coniferous forests

Treesearch

Christopher J. Fettig

2013-01-01

The future looks bright for the development and use of semiochemical-based tools in forests, particularly in remote and sensitive areas where other management techniques (e.g., the use of insecticides) may not be appropriate. This editorial provides an concise overview of chemical ecology and management of bark beetles in western coniferous forests.

California Report Card 2008: The State of the State's Children

ERIC Educational Resources Information Center

Children Now, 2008

2008-01-01

The California Report Card provides a clear, complete and concise picture of the state of the state's children along with recommendations for how we can better support our children through new and improved public policies. It assigns letter grades to such key indicators as health insurance, oral health, asthma, mental health, infant health,…

Northwestern University School of Speech: A History.

ERIC Educational Resources Information Center

Rein, Lynn Miller

This book presents a concise history of the first 100 years of development of the school of speech at Northwestern University (Illinois). Following an introduction that provides an overview of the school, the first chapter focuses on both the efforts of Robert McLean Cumnock to found a school of oratory on the principles of elocution and the…

Editors' Introduction to the Thematic Issue: Mad about Methods? Teaching Research Methods in Political Science

ERIC Educational Resources Information Center

Adriaensen, Johan; Kerremans, Bart; Slootmaeckers, Koen

2015-01-01

The contributors to this special issue all seek to address the challenge of teaching research methods to political science students. This introduction aims to provide a concise framework for the various innovations presented throughout this issue, situating them in the wider literature. Particular emphasis is placed on the factors that distinguish…

Skin-Color Prejudice and Within-Group Racial Discrimination: Historical and Current Impact on Latino/a Populations

ERIC Educational Resources Information Center

Chavez-Dueñas, Nayeli Y.; Adames, Hector Y.; Organista, Kurt C.

2014-01-01

The psychological literature on colorism, a form of within-group racial discrimination, is sparse. In an effort to contribute to this understudied area and highlight its significance, a concise and selective review of the history of colorism in Latin America is provided. Specifically, three historical eras (i.e., conquest, colonization, and…

Integrated Science Assessment (ISA) for Oxides of Nitrogen, Oxides of Sulfur and Particulate Matter Ecological Criteria (Second External Review Draft)

EPA Science Inventory

This draft Integrated Science Assessment (ISA) represents a concise synthesis and evaluation of the most policy-relevant science and will ultimately provide the scientific bases for EPA’s decision on retaining or revising the current secondary standards for NO₂, SO

17 CFR 162.5 - Contents of opt-out notice; consolidated and equivalent notices.

Code of Federal Regulations, 2012 CFR

2012-04-01

... Affiliate Marketing Rules § 162.5 Contents of opt-out notice; consolidated and equivalent notices. (a... conspicuous, as well as concise, and must accurately disclose the following: (i) (A) The name of the affiliate... notice; or (B) If jointly provided jointly by multiple affiliates and each affiliate shares a common name...

17 CFR 162.5 - Contents of opt-out notice; consolidated and equivalent notices.

Code of Federal Regulations, 2013 CFR

2013-04-01

... Affiliate Marketing Rules § 162.5 Contents of opt-out notice; consolidated and equivalent notices. (a... conspicuous, as well as concise, and must accurately disclose the following: (i) (A) The name of the affiliate... notice; or (B) If jointly provided jointly by multiple affiliates and each affiliate shares a common name...

17 CFR 162.5 - Contents of opt-out notice; consolidated and equivalent notices.

Code of Federal Regulations, 2014 CFR

2014-04-01

... Business Affiliate Marketing Rules § 162.5 Contents of opt-out notice; consolidated and equivalent notices... conspicuous, as well as concise, and must accurately disclose the following: (i) (A) The name of the affiliate... notice; or (B) If jointly provided jointly by multiple affiliates and each affiliate shares a common name...

1001 Best Internet Sites for Educators. 2nd Edition.

ERIC Educational Resources Information Center

Treadwell, Mark

This second edition of a resource designed to help teachers find relevant information on the Internet for both themselves and their students, provides concise reviews of more than 1,000 Web sites sorted by subject area. Each site is evaluated with one to five stars for content, presentation and grade level. Easy-to-follow explanations are provided…

Mathematical Creativity: Psychology, Progress and Caveats

ERIC Educational Resources Information Center

Sriraman, Bharath

2017-01-01

The aim of this paper is to provide a concise survey of advances in the study of the psychology of creativity, with an emphasis on literature that is typically not cited in mathematics education. In spite of claims that mathematical creativity is an ill-defined area of inquiry in mathematics education, the literature from psychology can serve as…

Reading Crisis: The Problem and Suggested Solutions. An EDUCATION U.S.A. Special Report.

ERIC Educational Resources Information Center

National School Public Relations Association, Washington, DC.

This report was written to provide the nation's education community with up-to-date information on the most significant recent studies on reading problems in concise, understandable language. Administrators, teachers, and school boards are anxious to improve their reading programs as part of the new national goal to end reading failures in America…

Suicide Prevention in the Schools: Guidelines for Middle and High School Settings. Second Edition

ERIC Educational Resources Information Center

Capuzzi, David

2009-01-01

In this book, David Capuzzi, a renowned expert on suicide, encourages suicide prevention in schools through the use of a clear and effective crisis management plan designed to identify and serve at-risk youth. His concise, step-by-step framework provides essential information for school counselors, administrators, and faculty on suicide…

Research Needs for Technology Education: A U.S. Perspective

ERIC Educational Resources Information Center

Martin, Gene; Ritz, John

2012-01-01

This study was conducted for the purpose of identifying research needs for technology education by generating a rank-ordered list of research topics that the profession's members might wish to explore individually or in collaboration with colleagues and students. The researchers' goal was to provide a concise list of topics that could be used by…

77 FR 16077 - License Amendment Request From Westinghouse Electric Company, LLC, Hematite Decommissioning Project

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-19

..., the petitioner must provide a specific statement of the issue of law or fact to be raised or... application. The petition must also include a concise statement of the alleged facts or expert opinions which... applicant on a material issue of law or fact, including references to specific portions of the application...

Policy Perspectives: No Merit in these Scholarships

ERIC Educational Resources Information Center

Vincent, Fay

2005-01-01

Mr. Fay Vincent, former Commissioner of Major League Baseball and Executive Vice President of The Coca Cola Company, provides a crisp, concise assessment of a trend that has worried us for quite a while: the growing trend of rewarding academically-gifted and typically-affluent students with an extra dose of merit aid, often at the expense of…

Jaundice in infants and children: causes, diagnosis and management.

PubMed

Chee, Y Y; Chung, P H; Wong, R M; Wong, K K

2018-05-21

Jaundice is caused by an accumulation of bilirubin in the blood. The presentation in infants and children can be indicative of a wide range of conditions, with some self-limiting and others potentially life-threatening. This article aims to provide a concise review of the common medical and surgical causes in children and discuss their diagnosis and management.

The Case Law on Student Teachers' Rights

ERIC Educational Resources Information Center

Karanxha, Zorka; Zirkel, Perry A.

2008-01-01

The article provides a concise and up-to-date synthesis of the published case law where a student teacher was the plaintiff, or suing party, and the defendant was an institution of higher education and/or the cooperating local school district. There were 28 of these court decisions, and the outcomes favored the defendant institutions in 23 of them…

Sorbian: The Sorbian Language in Education in Germany, 2nd Edition. Regional Dossiers Series

ERIC Educational Resources Information Center

Brezan, Beate, Comp.; Nowak, Meto, Comp.

2016-01-01

This regional dossier aims to provide a concise, description and basic statistics about minority language education in a specific region of Europe. Aspects that are addressed include features of the education system, recent educational policies, main actors, legal arrangements, and support structures, as well as quantitative aspects, such as the…

North Frisian: The North Frisian Language in Education in Germany, 3rd Edition. Regional Dossiers Series

ERIC Educational Resources Information Center

Walker, Alastair G. H., Comp.

2015-01-01

This regional dossier aims to provide a concise, description and basic statistics about minority language education in a specific region of Europe. Aspects that are addressed include features of the education system, recent educational policies, main actors, legal arrangements, and support structures, as well as quantitative aspects, such as the…

Swedish: The Swedish Language in Education in Finland, 2nd Edition. Regional Dossiers Series

ERIC Educational Resources Information Center

Østern, Anna-Lena, Comp.; Harju-Luukkainen, Heidi, Comp.

2013-01-01

This regional dossier aims to provide a concise, description and basic statistics about minority language education in a specific region of Europe. Aspects that are addressed include features of the education system, recent educational policies, main actors, legal arrangements, and support structures, as well as quantitative aspects, such as the…

Ladin: The Ladin Language in Education in Italy, 2nd Edition. Regional Dossiers Series

ERIC Educational Resources Information Center

Verra, Roland, Comp.

2016-01-01

This regional dossier aims to provide a concise, description and basic statistics about minority language education in a specific region of Europe. Aspects that are addressed include features of the education system, recent educational policies, main actors, legal arrangements, and support structures, as well as quantitative aspects, such as the…

Galician: The Galician Language in Education in Spain, 2nd Edition. Regional Dossiers Series

ERIC Educational Resources Information Center

Costas, Xosé-Henrique, Comp.; Expósito-Loureiro, Andrea, Comp.

2016-01-01

This regional dossier aims to provide a concise, description and basic statistics about minority language education in a specific region of Europe. Aspects that are addressed include features of the education system, recent educational policies, main actors, legal arrangements, and support structures, as well as quantitative aspects, such as the…

Welsh: The Welsh Language in Education in the UK, 2nd Edition. Regional Dossiers Series

ERIC Educational Resources Information Center

Jones, Meirion Prys, Comp.; Jones, Ceinwen, Comp.

2014-01-01

This regional dossier aims to provide a concise, description and basic statistics about minority language education in a specific region of Europe. Aspects that are addressed include features of the education system, recent educational policies, main actors, legal arrangements, and support structures, as well as quantitative aspects, such as the…

Irish: The Irish Language in Education in the Republic of Ireland, 2nd Edition. Regional Dossiers Series

ERIC Educational Resources Information Center

Ó Murchú, Helen, Comp.

2016-01-01

This regional dossier aims to provide a concise, description and basic statistics about minority language education in a specific region of Europe. Aspects that are addressed include features of the education system, recent educational policies, main actors, legal arrangements, and support structures, as well as quantitative aspects, such as the…

Asturian: The Asturian Language in Education in Spain, 2nd Edition. Regional Dossiers Series

ERIC Educational Resources Information Center

González-Riaño, Xosé Antón, Comp.; Fernández-Costales, Alberto, Comp.

2014-01-01

This regional dossier aims to provide a concise, description and basic statistics about minority language education in a specific region of Europe. Aspects that are addressed include features of the education system, recent educational policies, main actors, legal arrangements, and support structures, as well as quantitative aspects, such as the…

Lectures on Kähler Geometry - Series: London Mathematical Society Student Texts (No. 69)

NASA Astrophysics Data System (ADS)

Moroianu, Andrei

2004-03-01

Kähler geometry is a beautiful and intriguing area of mathematics, of substantial research interest to both mathematicians and physicists. This self-contained graduate text provides a concise and accessible introduction to the topic. The book begins with a review of basic differential geometry, before moving on to a description of complex manifolds and holomorphic vector bundles. Kähler manifolds are discussed from the point of view of Riemannian geometry, and Hodge and Dolbeault theories are outlined, together with a simple proof of the famous Kähler identities. The final part of the text studies several aspects of compact Kähler manifolds: the Calabi conjecture, Weitzenböck techniques, Calabi Yau manifolds, and divisors. All sections of the book end with a series of exercises and students and researchers working in the fields of algebraic and differential geometry and theoretical physics will find that the book provides them with a sound understanding of this theory. The first graduate-level text on Kähler geometry, providing a concise introduction for both mathematicians and physicists with a basic knowledge of calculus in several variables and linear algebra Over 130 exercises and worked examples Self-contained and presents varying viewpoints including Riemannian, complex and algebraic

Continuous Strategy Development for Effects-Based Operations

DTIC Science & Technology

2006-02-01

the probability of COA success. The time slider from the “Time Selector” choice in the View menu may also be used to animate the probability coloring...will Deploy WMD, since this can be assumed to have the inverse probability (1-P) of our objective. Clausewitz theory teaches us that an enemy must be... using XSLT, a concise language for transforming XML documents, for forward and reverse conversion between the SDT and SMS plan formats. 2. Develop a

HPV Testing of Head and Neck Cancer in Clinical Practice.

PubMed

Robinson, Max

The pathology laboratory has a central role in providing human papillomavirus (HPV) tests for patients with head and neck cancer. There is an extensive literature around HPV testing and a large number of proprietary HPV tests, which makes the field difficult to navigate. This review provides a concise contemporary overview of the evidence around HPV testing in head and neck cancer and signposts key publications, guideline documents and the most commonly used methods in clinical practice.

Concise total syntheses of (+/-)-strychnine and (+/-)-akuammicine.

PubMed

Sirasani, Gopal; Paul, Tapas; Dougherty, William; Kassel, Scott; Andrade, Rodrigo B

2010-05-21

Concise total syntheses of Strychnos alkaloids strychnine (1) and akuammicine (2) have been realized in 13 and 6 operations, respectively. Key steps include (1) the vinylogous Mannich reaction; (2) a novel, sequential one-pot spirocyclization/intramolecular aza-Baylis-Hillman reaction; and (3) a Heck cyclization. The synthesis of 1 proceeds via the Wieland-Gumlich aldehyde (26).

The Dirty Dozen: A Concise Measure of the Dark Triad

ERIC Educational Resources Information Center

Jonason, Peter K.; Webster, Gregory D.

2010-01-01

There has been an exponential increase of interest in the dark side of human nature during the last decade. To better understand this dark side, the authors developed and validated a concise, 12-item measure of the Dark Triad: narcissism, psychopathy, Machiavellianism. In 4 studies involving 1,085 participants, they examined its structural…

Reviews of environmental contamination and toxicology

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ware, G.

2007-07-01

Review of Environmental Contamination and Toxicology attempts to provide concise, critical reviews of timely advances, philosophy and significant areas of accomplished or needed endeavour in the total field of xenobiotics, in any segment of the environment, as well as toxicological implications. This edition contains a paper 'Health effects of arsenic, fluorine and selenium from indoor burning of Chinese coal, by Liu Guijian, Zheng Liugen, Nurdan S. Duzgoren-Aydin, Gao Lianfen, Liu Junhua, and Peng Zicheng. Other papers are: Chemistry and fate of simazine; Ethanol production: energy, economic, and environmental losses; Arsenic behaviour from groundwater and soil to crops: impacts on agriculturemore » and food safety; Mercury content of hair in different populations relative to fish consumption; and Toxicology of 1,3-butadiene, chloroprene, and isoprene. 15 ills.« less

The Essential Manual for Asperger Syndrome (ASD) in the Classroom: What Every Teacher Needs to Know

ERIC Educational Resources Information Center

Hoopmann, Kathy

2015-01-01

Perfect for time-poor teachers, Kathy Hoopmann's essential handbook is an easy-to-navigate resource that promotes a positive learning environment in which students with Asperger syndrome (ASD) can thrive. Kathy's unique ability to explain the ASD mind-set shines through as her concise descriptions reveal how to recognise and develop the child's…

Designing and Proposing Your Research Project. Concise Guides to Conducting Behavioral, Health, and Social Science Research Series

ERIC Educational Resources Information Center

Urban, Jennifer Brown; van Eeden-Moorefield, Bradley Matheus

2017-01-01

Designing your own study and writing your research proposal takes time, often more so than conducting the study. This practical, accessible guide walks you through the entire process. You will learn to identify and narrow your research topic, develop your research question, design your study, and choose appropriate sampling and measurement…

Introductory Talk: Adding Up Chemicals: Component-Based Risk Assessment of Chemical Mixturesand Primary Talk: Grouping Chemicals for Assessment and Conducting Assessments with the Hazard Index and Related Methods

EPA Science Inventory

Dr. Simmons will provide a concise overview of established and emerging methods to group chemicals for component-based mixture risk assessments. This will be followed by introduction to several important component-based methods, the Hazard Index, Target Organ Hazard Index, Multi...

Write to the Top! How to Become a Prolific Academic

ERIC Educational Resources Information Center

Johnson, W. Brad; Mullen, Carol A.

2007-01-01

This concise guide to writing is designed to help any academic become not only productive but truly prolific. It is a pithy, no-nonsense, no-excuses guide to maximizing the quality and quantity of scholarly output. The authors offer an accessible overview of the art of writing efficiently and effectively, provide a one-stop source for the nuts and…

Learning and memory in Octopus vulgaris: a case of biological plasticity.

PubMed

Zarrella, Ilaria; Ponte, Giovanna; Baldascino, Elena; Fiorito, Graziano

2015-12-01

Here we concisely summarize major aspects of the learning capabilities of the cephalopod mollusc Octopus vulgaris, a solitary living marine invertebrate. We aim to provide a backdrop against which neurobiology of these animals can be further interpreted and thus soliciting further interest for one of the most advanced members of invertebrate animals. Copyright © 2015 Elsevier Ltd. All rights reserved.

Concise synthesis of the hasubanan alkaloid (±)-cepharatine A using a Suzuki coupling reaction to effect o,p-phenolic coupling.

PubMed

Magnus, Philip; Seipp, Charles

2013-09-20

Suzuki coupling of 10 and 11 resulted in 9, which was O-alkylated to provide 12. Treatment of 12 with CsF in DMF resulted in the formation of the completed core structure 13 in a single step. Reductive amination of 13 completed the synthesis of (±)-cepharatine A, 4.

No Child Left Behind Primer. Second Printing. Peter Lang Primer Volume 11

ERIC Educational Resources Information Center

Hess, Frederick M.; Petrilli, Michael J.

2007-01-01

No Child Left Behind (NCLB) is the single most influential piece of federal education legislation in American history, and Hess and Petrilli provide a concise yet comprehensive look at this important and controversial act. Signed into law in 2002, NCLB seeks to ensure that all American students are proficient in math, reading, and science by 2014.…

Revised Evaluation of Health Effects Associated with Carbon Monoxide Exposure: An Addendum to the 1979 U.S. EPA Air Quality Criteria Document for Carbon Monoxide (1984)

EPA Science Inventory

The addendum re-evaluates the scientific data base concerning health effects associated with exposure to carbon monoxide (CO) at ambient or near ambient levels by providing: (1) a concise summary of key health effects information pertaining to relatively low-level CO exposure; an...

Facilitating Interdisciplinary Competence: Collaboration between Undergraduate Baccalaureate Nursing Students and Graduate Students Specializing in Communication Disorders

ERIC Educational Resources Information Center

McMillan, Libba Reed; Burrus, Embry; Willis, Laura; Grabowsky, Adelia

2016-01-01

The fast-paced nature of the healthcare setting, coupled with the number of allied professionals involved, demands accurate and concise written communication. It is imperative that written communication between nursing and allied professionals be clear to ensure that the highest quality of care is provided and that patient safety is maintained.…

75 FR 13786 - Biweekly Notice; Applications and Amendments to Facility Operating Licenses Involving No...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-23

.../petitioner shall provide a brief explanation of the bases for the contention and a concise statement of the...? Response: No. The Bases of TS 3.6.2.2 state that the operability of the Spray Additive System ensures that... ``Scram Discharge Volume (SDV) Vent and Drain Valves'' and associated Bases of NUREG-1433, Revision 3...

An Annotated Summary of the Regulation for Title IX Education Amendments of 1972.

ERIC Educational Resources Information Center

NETWORK, Inc., Andover, MA.

This document is one of a two-part set of publications. Both deal with equal education and provide a concise overview of Title IX and gender equity issues in education and steps to take to ensure nondiscrimination and equal education opportunity for all. Title IX of the Education Amendments of 1972 is the major federal law prohibiting sex…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sivaraman, Chitra

The purpose of this report is to provide a concise status update for value-added products (VAP) implemented by the Atmospheric Radiation Measurement Climate Research Facility. The report is divided into the following sections: (1) new VAPs for which development has begun, (2) progress on existing VAPs, (3) future VAPs that have been recently approved, (4) other work that leads to a VAP, and (5) top requested VAPs from the archive.

Master Curriculum Guide in Economics for the Nation's Schools. Part I, A Framework for Teaching Economics: Basic Concepts.

ERIC Educational Resources Information Center

Hansen, W. Lee; And Others

A concise framework of basic concepts and generalizations for teaching economics for K-12 students is presented. The guide summarizes the basic structure and substance of economics and lists and describes economic concepts. Standard guidelines are provided to help school systems integrate economics into their on-going courses of study. Designed to…

Bright Object Protection Considerations for M Dwarf Flare Events

NASA Astrophysics Data System (ADS)

Osten, R.

2017-02-01

We provide clear and concise guidance for Guest Observers and Contact Scientists to evaluate the health and safety of the instrument while observing M dwarfs, taking into consideration current scientific research about the frequency with which large flare events occur, and a risk tolerance level for causing an inadvertent detector shutdown due to overlight conditions from a large flare during an observation.

Still Red and in War or Just Poor? European Transformation Societies in Geography Textbooks

ERIC Educational Resources Information Center

Bagoly-Simo, Peter

2013-01-01

Textbooks are an important tool for teaching and learning in high school geography classrooms. But what sort of picture do they provide of places that are different and distant from the countries in which they are published? This study explores this question through a concise analysis of a widely used American world geography textbook, with a…

Transition Metal d-Orbital Splitting Diagrams: An Updated Educational Resource for Square Planar Transition Metal Complexes

ERIC Educational Resources Information Center

Bo¨rgel, Jonas; Campbell, Michael G.; Ritter, Tobias

2016-01-01

The presentation of d-orbital splitting diagrams for square planar transition metal complexes in textbooks and educational materials is often inconsistent and therefore confusing for students. Here we provide a concise summary of the key features of orbital splitting diagrams for square planar complexes, which we propose may be used as an updated…

Dramatherapy and Family Therapy in Education: Essential Pieces of the Multi-Agency Jigsaw

ERIC Educational Resources Information Center

McFarlane, Penny; Harvey, Jenny

2012-01-01

A collaborative therapeutic approach often proves the best way to assess and meet the needs of children experiencing barriers to learning. This book gives a concise overview of drama and family therapy and describes how both therapies can work together to provide essential pieces of the jigsaw of emotional support for troubled children within an…

Nenets, Khanty and Selkup: The Nenets, Khanty and Selkup Language in Education in the Yamal Region in Russia. Regional Dossiers Series

ERIC Educational Resources Information Center

Laptander, Roza Ivanovna, Comp.

2016-01-01

This regional dossier aims to provide a concise, description and basic statistics about minority language education in a specific region of Europe. Aspects that are addressed include features of the education system, recent educational policies, main actors, legal arrangements, and support structures, as well as quantitative aspects, such as the…

Cu(I)-catalyzed transannulation of N-heteroaryl aldehydes or ketones with alkylamines via C(sp3)-H amination.

PubMed

Li, Mingyang; Xie, Ying; Ye, Yong; Zou, Yong; Jiang, Huanfeng; Zeng, Wei

2014-12-05

A copper(I)-catalyzed direct transannulation of N-heteroaryl aldehydes or ketones with alkylamines via Csp(3)-H amination has been achieved using molecular oxygen as a sole oxidant. N-Heteroarenes are employed as the amine source. This transformation provides a rapid and concise access to multifunctional imidazo[1,5-a]pyridines.

Selected Tether Applications Cost Model

NASA Technical Reports Server (NTRS)

Keeley, Michael G.

1988-01-01

Diverse cost-estimating techniques and data combined into single program. Selected Tether Applications Cost Model (STACOM 1.0) is interactive accounting software tool providing means for combining several independent cost-estimating programs into fully-integrated mathematical model capable of assessing costs, analyzing benefits, providing file-handling utilities, and putting out information in text and graphical forms to screen, printer, or plotter. Program based on Lotus 1-2-3, version 2.0. Developed to provide clear, concise traceability and visibility into methodology and rationale for estimating costs and benefits of operations of Space Station tether deployer system.

Effectively using communication to enhance the provision of pediatric palliative care in an acute care setting.

PubMed

Hubble, Rosemary; Trowbridge, Kelly; Hubbard, Claudia; Ahsens, Leslie; Ward-Smith, Peggy

2008-08-01

The capability of effectively communicating is crucial when providing palliative care, especially when the patient is a child. Communication among healthcare professionals with the child and family members must be clear, concise, and consistent. Use of a communication tool provides documentation for conversations, treatment plans, and specific desires related to care. This paper describes communication theory, portrays the use of this theory to develop a communication tool, and illustrates the use of this tool by multidisciplinary members of a healthcare team to provide pediatric palliative care.

Concise solid-phase synthesis of inverse poly(amidoamine) dendrons using AB2 building blocks.

PubMed

Huang, Adela Ya-Ting; Tsai, Ching-Hua; Chen, Hsing-Yin; Chen, Hui-Ting; Lu, Chi-Yu; Lin, Yu-Ting; Kao, Chai-Lin

2013-06-28

A concise solid-phase synthesis of inverse poly(amidoamine) dendrons was developed. Upon introduction of AB2-type monomers, each dendron generation was constructed via one reaction. G2 to G5 dendrons were constructed in a peptide synthesizer in 93%, 89%, 82%, and 78% yields, respectively, within 5 days.

The Affective Reactivity Index: A Concise Irritability Scale for Clinical and Research Settings

ERIC Educational Resources Information Center

Stringaris, Argyris; Goodman, Robert; Ferdinando, Sumudu; Razdan, Varun; Muhrer, Eli; Leibenluft, Ellen; Brotman, Melissa A.

2012-01-01

Background: Irritable mood has recently become a matter of intense scientific interest. Here, we present data from two samples, one from the United States and the other from the United Kingdom, demonstrating the clinical and research utility of the parent- and self-report forms of the Affective Reactivity Index (ARI), a concise dimensional measure…

Synthetic study toward ecteinascidin 743: concise construction of the diazabicyclo[3.3.1]nonane skeleton and assembly of the pentacyclic core.

PubMed

Enomoto, Taro; Yasui, Yoshizumi; Takemoto, Yoshiji

2010-07-16

Synthesis of the pentacyclic core of ecteinascidin 743 is described. This synthesis features concise construction of the diazabicyclo[3.3.1]nonane skeleton using gold(I)-catalyzed one-pot keto amide formation, acid-promoted enamide formation, and oxidative Friedel-Crafts cyclization as the key steps.

Gastric precancerous diseases classification using CNN with a concise model.

PubMed

Zhang, Xu; Hu, Weiling; Chen, Fei; Liu, Jiquan; Yang, Yuanhang; Wang, Liangjing; Duan, Huilong; Si, Jianmin

2017-01-01

Gastric precancerous diseases (GPD) may deteriorate into early gastric cancer if misdiagnosed, so it is important to help doctors recognize GPD accurately and quickly. In this paper, we realize the classification of 3-class GPD, namely, polyp, erosion, and ulcer using convolutional neural networks (CNN) with a concise model called the Gastric Precancerous Disease Network (GPDNet). GPDNet introduces fire modules from SqueezeNet to reduce the model size and parameters about 10 times while improving speed for quick classification. To maintain classification accuracy with fewer parameters, we propose an innovative method called iterative reinforced learning (IRL). After training GPDNet from scratch, we apply IRL to fine-tune the parameters whose values are close to 0, and then we take the modified model as a pretrained model for the next training. The result shows that IRL can improve the accuracy about 9% after 6 iterations. The final classification accuracy of our GPDNet was 88.90%, which is promising for clinical GPD recognition.

Reynolds number scaling to predict droplet size distribution in dispersed and undispersed subsurface oil releases.

PubMed

Li, Pu; Weng, Linlu; Niu, Haibo; Robinson, Brian; King, Thomas; Conmy, Robyn; Lee, Kenneth; Liu, Lei

2016-12-15

This study was aimed at testing the applicability of modified Weber number scaling with Alaska North Slope (ANS) crude oil, and developing a Reynolds number scaling approach for oil droplet size prediction for high viscosity oils. Dispersant to oil ratio and empirical coefficients were also quantified. Finally, a two-step Rosin-Rammler scheme was introduced for the determination of droplet size distribution. This new approach appeared more advantageous in avoiding the inconsistency in interfacial tension measurements, and consequently delivered concise droplet size prediction. Calculated and observed data correlated well based on Reynolds number scaling. The relation indicated that chemical dispersant played an important role in reducing the droplet size of ANS under different seasonal conditions. The proposed Reynolds number scaling and two-step Rosin-Rammler approaches provide a concise, reliable way to predict droplet size distribution, supporting decision making in chemical dispersant application during an offshore oil spill. Copyright © 2016 Elsevier Ltd. All rights reserved.

THE HUMAN BEHAVIOR RATING SCALE-BRIEF: A TOOL TO MEASURE 21ST CENTURY SKILLS OF K-12 LEARNERS.

PubMed

Woods-Groves, Suzanne

2015-06-01

Currently there is a call for brief concise measurements to appraise relevant 21st century college readiness skills in K-12 learners. This study employed K-12 teachers' ratings for over 3,000 students for an existing 91-item rating scale, the Human Behavior Rating Scale, that measured the 21st century skills of persistence, curiosity, externalizing affect, internalizing affect, and cognition. Teachers' ratings for K-12 learners were used to develop a brief, concise, and manageable 30-item tool, the Human Behavior Rating Scale-Brief. Results yielded high internal consistency coefficients and inter-item correlations. The items were not biased with regard to student sex or race, and were supported through confirmatory factor analyses. In addition, when teachers' ratings were compared with students' academic and behavioral performance data, moderate to strong relationships were revealed. This study provided an essential first step in the development of a psychometrically sound, manageable, and brief tool to appraise 21st century skills in K-12 learners.

Frontiers of Theoretical Research on Shape Memory Alloys: A General Overview

NASA Astrophysics Data System (ADS)

Chowdhury, Piyas

2018-03-01

In this concise review, general aspects of modeling shape memory alloys (SMAs) are recounted. Different approaches are discussed under four general categories, namely, (a) macro-phenomenological, (b) micromechanical, (c) molecular dynamics, and (d) first principles models. Macro-phenomenological theories, stemming from empirical formulations depicting continuum elastic, plastic, and phase transformation, are primarily of engineering interest, whereby the performance of SMA-made components is investigated. Micromechanical endeavors are generally geared towards understanding microstructural phenomena within continuum mechanics such as the accommodation of straining due to phase change as well as role of precipitates. By contrast, molecular dynamics, being a more recently emerging computational technique, concerns attributes of discrete lattice structures, and thus captures SMA deformation mechanism by means of empirically reconstructing interatomic bonding forces. Finally, ab initio theories utilize quantum mechanical framework to peek into atomistic foundation of deformation, and can pave the way for studying the role of solid-sate effects. With specific examples, this paper provides concise descriptions of each category along with their relative merits and emphases.

Comparative evaluation of microleakage of lingual retainer wires bonded with three different lingual retainer composites: an in vitro study.

PubMed

Nimbalkar-Patil, Smita; Vaz, Anna; Patil, Pravinkumar G

2014-11-01

To evaluate microleakage when two types of retainer wires were bonded with two light cured and a self cured lingual retainer composites. Total 120 freshly extracted human mandibular incisor teeth were collected and separated into six subgroups of 20 teeth each. Two different wires, a 0.036 inch hard round stainless steel (HRSS) wire sandblasted at the ends and 0.0175 inch multistranded wire bonded onto the lingual surfaces of the incisors with three different types of composite resins of 3M company; Concise Orthodontic (self-cure), Transbond XT (light-cure) and Transbond LR (light-cure). Specimens were further sealed with a nail varnish, stained with 0.5% basic fuchsine for 24 hours, sectioned and examined under a stereomicroscope, and scored for microleakage for the enamel-composite and wire-composite interfaces. Statistical analysis was performed by Kruskal-Wallis and Mann-Whitney U-tests. For HRSS wire, at the enamel-composite interface, the microleakage was least with Transbond LR followed by Concise Orthodontic and greatest for Transbond XT (p<0.05). At the wire composite interface too, the microleakage was in order of Transbond LR

12 strategies for managing capital projects.

PubMed

Stoudt, Richard L

2013-05-01

To reduce the amount of time and cost associated with capital projects, healthcare leaders should: Begin the project with a clear objective and a concise master facilities plan. Select qualified team members who share the vision of the owner. Base the size of the project on a conservative business plan. Minimize incremental program requirements. Evaluate the cost impact of the building footprint. Consider alternative delivery methods.

A balanced perspective: using nonfinancial measures to assess financial performance.

PubMed

Watkins, Ann L

2003-11-01

Assessments of hospitals' financial performance have traditionally been based exclusively on analysis of a concise set of key financial ratios. One study, however, demonstrates that analysis of a hospital's financial condition can be significantly enhanced with the addition of several nonfinancial measures, including case-mix adjusted admissions, case-mix adjusted admissions per full-time equivalent, and case-mix adjusted admissions per beds in service.

Design of a Threat-Based Gunnery Performance Test: Issues and Procedures for Crew and Platoon Tank Gunnery

DTIC Science & Technology

1990-06-01

Uses visual communication . _._Changes direction/formation __Crews transmit timely, accurate quickly. messages. NOTES. Figure 22. Sample engagement...and concise. The network control station (NCS) effectively maintains network discipline. Radio security equipment, visual communication , wire...net discipline, (c) clarity and brevity of radio messages, (d) use of transmission security equipment, (e) use of visual communication , (f) use of wire

Concise, Stereocontrolled Synthesis of the Citrinadin B Core Architecture

PubMed Central

Guerrero, Carlos A.; Sorensen, Erik J.

2011-01-01

A concise, stereocontrolled synthesis of the citrinadin B core architecture from scalemic, readily available starting materials is disclosed. Highlights include ready access to both cyclic tryptophan tautomer and TRANS-2,6-disubstituted piperidine fragments, an efficient, stereoretentive mixed Claisen acylation for the coupling of these halves, and further diastereoselective carbonyl addition and oxidative rearrangement for assembly of the core. PMID:21894952

A brief introduction to the model microswimmer Chlamydomonas reinhardtii

NASA Astrophysics Data System (ADS)

Jeanneret, Raphaël; Contino, Matteo; Polin, Marco

2016-11-01

The unicellular biflagellate green alga Chlamydomonas reinhardtii has been an important model system in biology for decades, and in recent years it has started to attract growing attention also within the biophysics community. Here we provide a concise review of some of the aspects of Chlamydomonas biology and biophysics most immediately relevant to physicists that might be interested in starting to work with this versatile microorganism.

MEXICAN-AMERICAN STUDY PROJECT. ADVANCE REPORT 8, MEXICAN-AMERICANS IN A MIDWEST METROPOLIS--A STUDY OF EAST CHICAGO.

ERIC Educational Resources Information Center

LAMANNA, RICHARD A.; SAMORA, JULIAN

MEXICAN AMERICANS WHO HAVE MIGRATED TO THE INDUSTRIAL COMPLEX OF EAST CHICAGO ARE ANALYZED TO DETERMINE THE VALIDITY OF A HYPOTHESIS THAT THIS GROUP WAS PROVIDED OPPORTUNITIES NOT AVAILABLE TO THEIR COUNTERPARTS IN THE SOUTHWEST FOR ASSIMILATION INTO THE COMMUNITY. A CONCISE REPORT ON THE HISTORY OF THE MEXICAN-AMERICAN COLONY IN EAST CHICAGO, ITS…

Education in the Arab Region Viewed from the 1970 Marrakesh Conference. Educational Studies and Documents Number 1.

ERIC Educational Resources Information Center

El-Ghannam, Mohammed A.

Designed to provide a comprehensive and concise picture of education in the Arab region, this booklet is the outgrowth of one of a series of conferences organized by UNESCO. The material is organized into three sections: the social and economic background of the Arab region; recent achievements and existing problems of education in the Arab…

Deep space network: Mission support requirements

NASA Technical Reports Server (NTRS)

1991-01-01

The purpose is to provide NASA and Jet Propulsion Laboratory management with a concise summary of information concerning the forecasting of the necessary support and requirements for missions described here, including the Earth Radiation Budget Experiment, the Cosmic Background Explorer, the Comet Rendezvous Asteroid Flyby, the Cassini, and the Dynamics Explorer-1. A brief description of various missions along with specific support requirements for each are given.

Bright Object Protection (BOP) Considerations for M Dwarf Flare Events

NASA Astrophysics Data System (ADS)

Osten, R.

2017-02-01

We provide clear and concise guidance for Guest Observers and Contact Scientists to evaluate the health and safety of the instrument when observing M dwarfs, taking into consideration current scientific research about the frequency with which large flare events occur, and a risk tolerance level for causing an inadvertent detector shutdown due to overlight conditions from a large flare during an observation.

Integrated Science Assessment (ISA) for Oxides of Nitrogen, Oxides of Sulfur and Particulate Matter - Ecological Criteria (First External Review Draft, Mar 2017)

EPA Science Inventory

This draft ISA document represents a concise synthesis and evaluation of the most policy-relevant science and will ultimately provide the scientific bases for EPA’s decision on retaining or revising the current secondary standards for NO2, SO2, PM 2.5 and PM 10 since the prior re...

ACRF Instrumentation Status: New, Current, and Future - October – November 2007

DOE Office of Scientific and Technical Information (OSTI.GOV)

JW Voyles

2007-11-30

The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement (ARM) Climate Research Facility (ACRF) instrumentation status. The report is divided into the following four sections: (1) new instrumentation in the process of being acquired and deployed, (2) existing instrumentation and progress on improvements or upgrades, (3) proposed future instrumentation, and (4) SBIR instrument development.

Valuing patient and caregiver time: a review of the literature.

PubMed

Tranmer, Jennifer E; Guerriere, Denise N; Ungar, Wendy J; Coyte, Peter C

2005-01-01

As healthcare expenditures continue to rise, financial pressures have resulted in a desire for countries to shift resources away from traditional areas of spending. The consequent devolution and reform have resulted in increased care being provided and received within homes and communities, and in an increased reliance on unpaid caregivers. Recent empirical work indicates that costs incurred by care recipients and unpaid caregivers, including time and productivity costs, often account for significant proportions of total healthcare expenditures. However, many economic evaluations do not include these costs. Moreover, when indirect costs are assessed, the methods of valuation are inconsistent and frequently controversial. This paper provides an overview and critique of existing valuation methods. Current methods such as the human capital method, friction cost method and the Washington Panel approach are presented and critiqued according to criteria such as potential for inaccuracy, ease of application, and ethical and distributional concerns. The review illustrates the depth to which the methods have been theoretically examined, and highlights a paucity of research on costs that accrue to unpaid caregivers and a lack of research on time lost from unpaid labour and leisure. To ensure accurate and concise reporting of all time costs, it is concluded that a broad conceptual approach for time costing should be developed that draws on and then expands upon theoretical work to date.

Day surgery nurses' selection of patient preoperative information.

PubMed

Mitchell, Mark

2017-01-01

To determine selection and delivery of preoperative verbal information deemed important by nurses to relay to patients immediately prior to day surgery. Elective day-case surgery is expanding, patient turnover is high and nurse-patient contact limited. In the brief time-frame available, nurses must select and precisely deliver information to patients, provide answers to questions and gain compliance to ensure a sustained, co-ordinated patient throughput. Concise information selection is therefore necessary especially given continued day surgery expansion. Electronic questionnaire. A survey investigating nurses' choice of patient information prior to surgery was distributed throughout the UK via email addresses listed on the British Association of Day Surgery member's website (January 2015-April 2015). Participants were requested to undertake the survey within 2-3 weeks, with 137 participants completing the survey giving a 44% response rate. Verbal information deemed most important by nurses preoperatively was checking fasting time, information about procedure/operation, checking medication, ensuring presence of medical records/test results and concluding medical investigations checks. To a lesser extent was theatre environment information, procedure/operation start time and possible time to discharge. Significant differences were established between perceived importance of information and information delivery concerning the procedure/operation and anaesthesia details. Nurses working with competing demands and frequent interruptions, prioritised patient safety information. Although providing technical details during time-limited encounters, efforts were made to individualise provision. A more formal plan of verbal information provision could help ease nurses' cognitive workload and enhance patient satisfaction. This study provides evidence that verbal information provided immediately prior to day surgery may vary with experience. Nurse educators and managers may need to provide greater guidance for such complex care settings as delivery of increasingly technical details during brief encounters is gaining increasing priority. © 2016 John Wiley & Sons Ltd.

Short temporal asynchrony disrupts visual object recognition

PubMed Central

Singer, Jedediah M.; Kreiman, Gabriel

2014-01-01

Humans can recognize objects and scenes in a small fraction of a second. The cascade of signals underlying rapid recognition might be disrupted by temporally jittering different parts of complex objects. Here we investigated the time course over which shape information can be integrated to allow for recognition of complex objects. We presented fragments of object images in an asynchronous fashion and behaviorally evaluated categorization performance. We observed that visual recognition was significantly disrupted by asynchronies of approximately 30 ms, suggesting that spatiotemporal integration begins to break down with even small deviations from simultaneity. However, moderate temporal asynchrony did not completely obliterate recognition; in fact, integration of visual shape information persisted even with an asynchrony of 100 ms. We describe the data with a concise model based on the dynamic reduction of uncertainty about what image was presented. These results emphasize the importance of timing in visual processing and provide strong constraints for the development of dynamical models of visual shape recognition. PMID:24819738

An introduction to DARC technology.

PubMed

Ahmad, Syed Shoeb

2017-01-01

Glaucoma is a multi-factorial neurodegenerative disorder. The common denominator in all types of glaucomas is retinal ganglion cell death through apoptosis. However, this cellular demise in glaucoma is detected late by structural or functional analyses. There can be a 10-year delay prior to the appearance of visual field defects and pre-perimetric glaucoma is an issue still being addressed. However, a new cutting-edge technology called detection of apoptosing retinal cells (DARC) is being developed. This technique is capable of non-invasive, real-time visualization of apoptotic changes at the cellular level. It can detect glaucomatous cell damage at a very early stage, at the moment apoptosis starts, and thus management can be initiated even prior to development of visual field changes. In future, this technique will also be able to provide conclusive evidence of the effectiveness of treatment protocol and the need for any modifications which may be required. This article aims to provide a concise review of DARC technology.

Advanced medical imaging protocol workflow-a flexible electronic solution to optimize process efficiency, care quality and patient safety in the National VA Enterprise.

PubMed

Medverd, Jonathan R; Cross, Nathan M; Font, Frank; Casertano, Andrew

2013-08-01

Radiologists routinely make decisions with only limited information when assigning protocol instructions for the performance of advanced medical imaging examinations. Opportunity exists to simultaneously improve the safety, quality and efficiency of this workflow through the application of an electronic solution leveraging health system resources to provide concise, tailored information and decision support in real-time. Such a system has been developed using an open source, open standards design for use within the Veterans Health Administration. The Radiology Protocol Tool Recorder (RAPTOR) project identified key process attributes as well as inherent weaknesses of paper processes and electronic emulators of paper processes to guide the development of its optimized electronic solution. The design provides a kernel that can be expanded to create an integrated radiology environment. RAPTOR has implications relevant to the greater health care community, and serves as a case model for modernization of legacy government health information systems.

Teaching evidence-based practice at the University of Texas Health Science Center at San Antonio dental school.

PubMed

Rugh, John D; Hendricson, William D; Glass, Birgit J; Hatch, John P; Deahl, S Thomas; Guest, Gary; Ongkiko, Richard; Gureckis, Kevin; Jones, Archie A; Rose, William F; Gakunga, Peter; Stark, Debra; Steffensen, Bjorn

2011-02-01

The overarching goal of the Evidence-Based Practice Program at San Antonio is to provide our graduates with life-long learning skills that will enable them to keep up-to-date and equip them with the best possible patient care skills during their 30-40 years of practice. Students are taught to (1) ask focused clinical questions, (2) search the biomedical research literature (PubMed) for the most recent and highest level of evidence, (3) critically evaluate the evidence, and (4) make clinical judgments about the applicability of the evidence for their patients. Students must demonstrate competency with these "just-in-time" learning skills through writing concise one-page Critically Appraised Topics (CATs) on focused clinical questions. The school has established an online searchable library of these Critically Appraised Topics. This library provides students and faculty with rapid, up-to-date evidence-based answers to clinical questions. The long-range plan is to make this online library available to practitioners and the public.

A Summary of Best Management Practices for Nonpoint Source Pollution

DTIC Science & Technology

1992-08-01

200-1, Environmental Protection and Enhancement, requies that NPS pollution be minimized and that Army installations and major commands comply with...Federal and state regula- tions. However, environmental managers and engineers have no concise summary of alterna- tives available for NPS pollution... environmental managers and engineers have no concise summary of alternatives available for NPS pollution control. This report presents a range of

Recognizing and managing type 2 diabetes mellitus in children: an algorithm for primary care providers.

PubMed

Sunni, Muna; Mays, Rita; Kaup, Tara; Nathan, Brandon

2011-08-01

During the last two decades, type 2 diabetes mellitus increasingly has been seen in children. Although still not as common as type 1 diabetes among children, it has become the leading form of diabetes among adolescents of certain ethnicities. It is imperative that primary care providers recognize the risk factors, perform appropriate screening tests, and initiate therapy for children who have type 2 diabetes or prediabetes. This article discusses the epidemiology and pathogenesis of the disease, complications, and treatments, and includes a concise, easy-to-follow algorithm to assist providers in diagnosing and treating young patients.

Physician Perspectives of CYP2C19 and Clopidogrel Drug-Gene Interaction Active Clinical Decision Support Alerts

PubMed Central

Nishimura, Adam A.; Shirts, Brian H.; Salama, Joseph; Smith, Joe W.; Devine, Beth; Tarczy-Hornoch, Peter

2015-01-01

Objective To determine if physicians find clinical decision support alerts for pharmacogenomic drug-gene interactions useful and assess their perceptions of usability aspects that impact usefulness. Materials and Methods 52 physicians participated in an online simulation and questionnaire involving a prototype alert for the clopidogrel and CYP2C19 drug-gene interaction. Results Only 4% of participants stated they would override the alert. 92% agreed that the alerts were useful. 87% found the visual interface appropriate, 91% felt the timing of the alert was appropriate and 75% were unfamiliar with the specific drug-gene interaction. 80% of providers preferred the ability to order the recommended medication within the alert. Qualitative responses suggested that supplementary information is important, but should be provided as external links, and that the utility of pharmacogenomic alerts depends on the broader ecosystem of alerts. Principal Conclusions Pharmacogenomic alerts would be welcomed by many physicians, can be built with minimalist design principles, and are appropriately placed at the end of the prescribing process. Since many physicians lack familiarity with pharmacogenomics but have limited time, information and educational resources within the alert should be carefully selected and presented in concise ways. PMID:26642939

Physician perspectives of CYP2C19 and clopidogrel drug-gene interaction active clinical decision support alerts.

PubMed

Nishimura, Adam A; Shirts, Brian H; Salama, Joseph; Smith, Joe W; Devine, Beth; Tarczy-Hornoch, Peter

2016-02-01

To determine if physicians find clinical decision support alerts for pharmacogenomic drug-gene interactions useful and assess their perceptions of usability aspects that impact usefulness. 52 physicians participated in an online simulation and questionnaire involving a prototype alert for the clopidogrel and CYP2C19 drug-gene interaction. Only 4% of participants stated they would override the alert. 92% agreed that the alerts were useful. 87% found the visual interface appropriate, 91% felt the timing of the alert was appropriate and 75% were unfamiliar with the specific drug-gene interaction. 80% of providers preferred the ability to order the recommended medication within the alert. Qualitative responses suggested that supplementary information is important, but should be provided as external links, and that the utility of pharmacogenomic alerts depends on the broader ecosystem of alerts. Pharmacogenomic alerts would be welcomed by many physicians, can be built with minimalist design principles, and are appropriately placed at the end of the prescribing process. Since many physicians lack familiarity with pharmacogenomics but have limited time, information and educational resources within the alert should be carefully selected and presented in concise ways. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Real time gamma-ray signature identifier

DOEpatents

Rowland, Mark [Alamo, CA; Gosnell, Tom B [Moraga, CA; Ham, Cheryl [Livermore, CA; Perkins, Dwight [Livermore, CA; Wong, James [Dublin, CA

2012-05-15

A real time gamma-ray signature/source identification method and system using principal components analysis (PCA) for transforming and substantially reducing one or more comprehensive spectral libraries of nuclear materials types and configurations into a corresponding concise representation/signature(s) representing and indexing each individual predetermined spectrum in principal component (PC) space, wherein an unknown gamma-ray signature may be compared against the representative signature to find a match or at least characterize the unknown signature from among all the entries in the library with a single regression or simple projection into the PC space, so as to substantially reduce processing time and computing resources and enable real-time characterization and/or identification.

Nickel-Catalyzed Addition-Type Alkenylation of Unactivated, Aliphatic C-H Bonds with Alkynes: A Concise Route to Polysubstituted γ-Butyrolactones.

PubMed

Li, Mingliang; Yang, Yudong; Zhou, Danni; Wan, Danyang; You, Jingsong

2015-05-15

Through the nickel-catalyzed chelation-assisted C-H bond activation strategy, the addition-type alkenylation of unreactive β-C(sp(3))-H bonds of aliphatic amides with internal alkynes is developed for the first time to produce γ,δ-unsaturated carboxylic amide derivatives. The resulting alkenylated products can further be transformed into polysubstituted γ-butyrolactones with pyridinium chlorochromate (PCC).

Using Common Graphics Paradigms Implemented in a Java Applet to Represent Complex Scheduling Requirements

NASA Technical Reports Server (NTRS)

Jaap, John; Meyer, Patrick; Davis, Elizabeth

1997-01-01

The experiments planned for the International Space Station promise to be complex, lengthy and diverse. The scarcity of the space station resources will cause significant competition for resources between experiments. The scheduling job facing the Space Station mission planning software requires a concise and comprehensive description of the experiments' requirements (to ensure a valid schedule) and a good description of the experiments' flexibility (to effectively utilize available resources). In addition, the continuous operation of the station, the wide geographic dispersion of station users, and the budgetary pressure to reduce operations manpower make a low-cost solution mandatory. A graphical representation of the scheduling requirements for station payloads implemented via an Internet-based application promises to be an elegant solution that addresses all of these issues. The graphical representation of experiment requirements permits a station user to describe his experiment by defining "activities" and "sequences of activities". Activities define the resource requirements (with alternatives) and other quantitative constraints of tasks to be performed. Activities definitions use an "outline" graphics paradigm. Sequences define the time relationships between activities. Sequences may also define time relationships with activities of other payloads or space station systems. Sequences of activities are described by a "network" graphics paradigm. The bulk of this paper will describe the graphical approach to representing requirements and provide examples that show the ease and clarity with which complex requirements can be represented. A Java applet, to run in a web browser, is being developed to support the graphical representation of payload scheduling requirements. Implementing the entry and editing of requirements via the web solves the problems introduced by the geographic dispersion of users. Reducing manpower is accomplished by developing a concise representation which eliminates the misunderstanding possible with verbose representations and which captures the complete requirements and flexibility of the experiments.

DISCRETE COMPOUND POISSON PROCESSES AND TABLES OF THE GEOMETRIC POISSON DISTRIBUTION.

DTIC Science & Technology

A concise summary of the salient properties of discrete Poisson processes , with emphasis on comparing the geometric and logarithmic Poisson processes . The...the geometric Poisson process are given for 176 sets of parameter values. New discrete compound Poisson processes are also introduced. These...processes have properties that are particularly relevant when the summation of several different Poisson processes is to be analyzed. This study provides the

Annual report, fiscal years 2001 and 2002

USGS Publications Warehouse

Raese, Jon W.

2003-01-01

The U.S. Geological Survey National Water Quality Laboratory annual report is designed to recap the important changes, contributions, and successes of the Laboratory over the past 2 fiscal years. The intent is to provide customers with a concise overview of what the Laboratory has accomplished, how it has performed, and how the assests entrusted to NWQL have been used to further the mission of the U.S. Geological Survey.

Tarsometatarsal arthrodesis for management of unstable first ray and failed bunion surgery.

PubMed

Espinosa, Norman; Wirth, Stephan H

2011-03-01

This article focuses on arthrodesis of the first tarsometatarsal joint as the primary intervention to treat hypermobility of the first ray or as a salvage procedure to treat prior failed bunion surgery and provides a concise review including historical perspective, definitions, pathomechanics, and treatment of specific forefoot disorders (ie, hypermobility of the first ray and failed bunion surgery). Copyright © 2011 Elsevier Inc. All rights reserved.

Swallowing and Secretion Management in Neuromuscular Disease.

PubMed

Britton, Deanna; Karam, Chafic; Schindler, Joshua S

2018-06-01

Neuromuscular disease frequently leads to dysphagia and difficulty managing secretions. Dysphagia may lead to medical complications, such as malnutrition, dehydration, aspiration pneumonia, and other pulmonary complications, as well as social isolation and reduced overall quality of life. This review provides an overview of dysphagia associated with neuromuscular disease in adults, along with a concise review of swallowing assessment and intervention options. Copyright © 2018 Elsevier Inc. All rights reserved.

'Renewables-Friendly' Grid Development Strategies: Experience in the United States, Potential Lessons for China (Chinese Translation) (in Chinese)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hurlbut, David; Zhou, Ella; Porter, Kevin

2015-10-03

This is a Chinese translation of NREL/TP-6A20-64940. This report aims to help China's reform effort by providing a concise summary of experience in the United States with 'renewables-friendly' grid management, focusing on experiences that might be applicable to China. It focuses on utility-scale renewables and sets aside issues related to distributed generation.

Search and Retrieval Index to EOS/ESD Symposium Proceedings - 1979 to 1984.

DTIC Science & Technology

1985-04-15

This book contains indexes used in searching for information contained in papers produced in Electrical Overstress/Electrostatic Discharge (EOS/ESD) Symposium 1979 to 1984. These indexes are the Alphabetical List of Index Terms, Subject Index, Author Index , Corporate Index, Keywords in Title Index, and Chronological List of Papers Index. These indexes provide a clear, easy-to-read, and concise method of searching for and

Laryngeal High-Speed Videoendoscopy: Rationale and Recommendation for Accurate and Consistent Terminology

PubMed Central

Deliyski, Dimitar D.; Hillman, Robert E.

2015-01-01

Purpose The authors discuss the rationale behind the term laryngeal high-speed videoendoscopy to describe the application of high-speed endoscopic imaging techniques to the visualization of vocal fold vibration. Method Commentary on the advantages of using accurate and consistent terminology in the field of voice research is provided. Specific justification is described for each component of the term high-speed videoendoscopy, which is compared and contrasted with alternative terminologies in the literature. Results In addition to the ubiquitous high-speed descriptor, the term endoscopy is necessary to specify the appropriate imaging technology and distinguish among modalities such as ultrasound, magnetic resonance imaging, and nonendoscopic optical imaging. Furthermore, the term video critically indicates the electronic recording of a sequence of optical still images representing scenes in motion, in contrast to strobed images using high-speed photography and non-optical high-speed magnetic resonance imaging. High-speed videoendoscopy thus concisely describes the technology and can be appended by the desired anatomical nomenclature such as laryngeal. Conclusions Laryngeal high-speed videoendoscopy strikes a balance between conciseness and specificity when referring to the typical high-speed imaging method performed on human participants. Guidance for the creation of future terminology provides clarity and context for current and future experiments and the dissemination of results among researchers. PMID:26375398

Thermal radiation analysis system TRASYS 2: User's manual

NASA Technical Reports Server (NTRS)

Goble, R. G.; Jensen, C. L.

1980-01-01

The Thermal Radiation Analyzer System (TRASYS) program put thermal radiation analysis on the same basis as thermal analysis using program systems such as MITAS and SINDA. The user is provided the powerful options of writing his own executive, or driver logic and choosing, among several available options, the most desirable solution technique(s) for the problem at hand. This User's Manual serves the twofold purpose of instructing the user in all applications and providing a convenient reference book that presents the features and capabilities in a concise, easy-to-find manner.

An Overview of Alopecias

PubMed Central

Qi, Ji; Garza, Luis A.

2014-01-01

Hair loss is a topic of enormous public interest and understanding the pathophysiology and treatment of various alopecias will likely make a large impact on patients’ lives. The investigation of alopecias also provides important insight in the basic sciences; for instance, the abundance of stem cell populations and regenerative cycles that characterize a hair follicle render it an excellent model for the study of stem cell biology. This review seeks to provide a concise summary of the major alopecias with regard to presentation and management, and correlate these to recent advances in relevant research on pathogenesis. PMID:24591533

Integrated Science Assessment (ISA) of Ozone and Related ...

EPA Pesticide Factsheets

EPA announced the availability of the final report, Integrated Science Assessment of Ozone and Related Photochemical Oxidants. This document represents a concise synthesis and evaluation of the most policy-relevant science and will ultimately provide the scientific bases for EPA’s decision regarding the adequacy of the current national ambient air quality standards for ozone to protect human health, public welfare, and the environment. Critical evaluation and integration of the evidence on health and environmental effects of ozone to provide scientific support for the review of the NAAQS for ozone.

Time-dependent structural transformation analysis to high-level Petri net model with active state transition diagram.

PubMed

Li, Chen; Nagasaki, Masao; Saito, Ayumu; Miyano, Satoru

2010-04-01

With an accumulation of in silico data obtained by simulating large-scale biological networks, a new interest of research is emerging for elucidating how living organism functions over time in cells. Investigating the dynamic features of current computational models promises a deeper understanding of complex cellular processes. This leads us to develop a method that utilizes structural properties of the model over all simulation time steps. Further, user-friendly overviews of dynamic behaviors can be considered to provide a great help in understanding the variations of system mechanisms. We propose a novel method for constructing and analyzing a so-called active state transition diagram (ASTD) by using time-course simulation data of a high-level Petri net. Our method includes two new algorithms. The first algorithm extracts a series of subnets (called temporal subnets) reflecting biological components contributing to the dynamics, while retaining positive mathematical qualities. The second one creates an ASTD composed of unique temporal subnets. ASTD provides users with concise information allowing them to grasp and trace how a key regulatory subnet and/or a network changes with time. The applicability of our method is demonstrated by the analysis of the underlying model for circadian rhythms in Drosophila. Building ASTD is a useful means to convert a hybrid model dealing with discrete, continuous and more complicated events to finite time-dependent states. Based on ASTD, various analytical approaches can be applied to obtain new insights into not only systematic mechanisms but also dynamics.

How to ask and what to do: A guide for clinical inquiry and intervention regarding female sexual health after cancer

PubMed Central

Bober, Sharon L.; Reese, Jennifer B.; Barbera, Lisa; Bradford, Andrea; Carpenter, Kristen M.; Goldfarb, Shari; Carter, Jeanne

2016-01-01

Purpose of review As the number of female cancer survivors continues to grow, there is a growing need to bridge the gap between the high rate of women's cancer-related sexual dysfunction and the lack of attention and intervention available to the majority of survivors who suffer from sexual problems. Previously identified barriers that hinder communication for providers include limited time, lack of preparation, and a lack of patient resources and access to appropriate referral sources. Recent findings This paper brings together a recently developed model for approaching clinical inquiry about sexual health with a brief problem checklist that has been adapted for use for female cancer survivors, as well as practical evidence-based strategies on how to address concerns identified on the checklist. Examples of patient education sheets are provided, as well as strategies for building a referral network. Summary By providing access to a concise and efficient tool for clinical inquiry, as well as targeted material resources and practical health-promoting strategies based on recent evidence-based findings, we hope to begin eliminating the barriers that hamper oncology providers from addressing the topic of sexual/vaginal health after cancer. PMID:26716390

Perinatal Anxiety: Approach to Diagnosis & Management in the Obstetric Setting.

PubMed

Thorsness, Katie R; Watson, Corey; Larusso, Elizabeth M

2018-05-24

Anxiety is common in women during the perinatal period, manifests with various symptomatology and severity, and is associated with significant maternal morbidity and adverse obstetrical and neonatal outcomes. Given the intimate relationship and frequency of contact, the obstetric provider is optimally positioned to create a therapeutic alliance and manage perinatal anxiety. Time constraints, absence of randomized controlled trials, mixed quality of data, and concern for potential adverse reproductive outcomes all limit clinicians' ability to initiate informed risk-benefit discussions. Clear understanding of the role of the obstetric provider in the identification, stabilization, and initiation of medication and/or referral to psychotherapy for women with perinatal anxiety disorders is critical to maternal and neonatal wellbeing. Informed by our clinical practice as perinatal psychiatric providers, we have provided a concise summary of current research on the approach to treatment of perinatal anxiety disorders in the obstetric setting, including psychotherapy and supportive interventions, primary and adjuvant psychiatric medication, and general prescribing pearls. Medications examined include antidepressants, benzodiazepines, sedative-hypnotics, antihistamines, quetiapine, buspirone, propranolol, and melatonin. Further research into management of perinatal anxiety, particularly psychopharmacological management, is warranted. Copyright © 2018 Elsevier Inc. All rights reserved.

Hybrid automated reliability predictor integrated work station (HiREL)

NASA Technical Reports Server (NTRS)

Bavuso, Salvatore J.

1991-01-01

The Hybrid Automated Reliability Predictor (HARP) integrated reliability (HiREL) workstation tool system marks another step toward the goal of producing a totally integrated computer aided design (CAD) workstation design capability. Since a reliability engineer must generally graphically represent a reliability model before he can solve it, the use of a graphical input description language increases productivity and decreases the incidence of error. The captured image displayed on a cathode ray tube (CRT) screen serves as a documented copy of the model and provides the data for automatic input to the HARP reliability model solver. The introduction of dependency gates to a fault tree notation allows the modeling of very large fault tolerant system models using a concise and visually recognizable and familiar graphical language. In addition to aiding in the validation of the reliability model, the concise graphical representation presents company management, regulatory agencies, and company customers a means of expressing a complex model that is readily understandable. The graphical postprocessor computer program HARPO (HARP Output) makes it possible for reliability engineers to quickly analyze huge amounts of reliability/availability data to observe trends due to exploratory design changes.

Rule extraction from minimal neural networks for credit card screening.

PubMed

Setiono, Rudy; Baesens, Bart; Mues, Christophe

2011-08-01

While feedforward neural networks have been widely accepted as effective tools for solving classification problems, the issue of finding the best network architecture remains unresolved, particularly so in real-world problem settings. We address this issue in the context of credit card screening, where it is important to not only find a neural network with good predictive performance but also one that facilitates a clear explanation of how it produces its predictions. We show that minimal neural networks with as few as one hidden unit provide good predictive accuracy, while having the added advantage of making it easier to generate concise and comprehensible classification rules for the user. To further reduce model size, a novel approach is suggested in which network connections from the input units to this hidden unit are removed by a very straightaway pruning procedure. In terms of predictive accuracy, both the minimized neural networks and the rule sets generated from them are shown to compare favorably with other neural network based classifiers. The rules generated from the minimized neural networks are concise and thus easier to validate in a real-life setting.

A concise and practical stereoselective synthesis of ipragliflozin L-proline

PubMed Central

Ma, Shuai; Liu, Zhenren; Pan, Jing; Zhang, Shunli

2017-01-01

A concise and practical stereoselective synthesis of ipragliflozin L-proline was presented starting from 2-[(5-iodo-2-fluorophenyl)methyl]-1-benzothiophene and 2,3,4,6-tetra-O-pivaloyl-α-D-glucopyranosyl bromide without catalyst via iodine–lithium–zinc exchange. The overall yield was 52% in three steps and the product purity was excellent. Two key diastereomers were prepared with efficient and direct access to the α-C-arylglucoside. PMID:28684985

Mental Representations Formed From Educational Website Formats

DOE Office of Scientific and Technical Information (OSTI.GOV)

Elizabeth T. Cady; Kimberly R. Raddatz; Tuan Q. Tran

2006-10-01

The increasing popularity of web-based distance education places high demand on distance educators to format web pages to facilitate learning. However, limited guidelines exist regarding appropriate writing styles for web-based distance education. This study investigated the effect of four different writing styles on reader’s mental representation of hypertext. Participants studied hypertext written in one of four web-writing styles (e.g., concise, scannable, objective, and combined) and were then administered a cued association task intended to measure their mental representations of the hypertext. It is hypothesized that the scannable and combined styles will bias readers to scan rather than elaborately read, whichmore » may result in less dense mental representations (as identified through Pathfinder analysis) relative to the objective and concise writing styles. Further, the use of more descriptors in the objective writing style will lead to better integration of ideas and more dense mental representations than the concise writing style.« less

Intelligent Mobile Autonomous System

DTIC Science & Technology

1987-01-01

used intermittently , and each of them characterizes the level of generalization. One cannot discern any another point within the tile, this is a...traversability space is not fast enough to be considered for actual control application. Alternatives to limit the computation time include (1) increasing the...error. (b) It must be concise and easy to "compute". In other words there must exist simple, fast procedures for instandating the "words" or "sentences

The NMatrix, a new method of presenting statistics, displays the characteristics of medicines with similar effects used in the treatment of lumbar spinal stenosis concisely and clearly, facilitating the selection of appropriate medications.

PubMed

Nakamura, Masao

2015-07-01

It is often difficult to compare the characteristics of a medicine with those of others based on common standards, whereas the application of rational standards would be expected to facilitate the comparison of medicines with similar effects. The present study was conducted to clarify the characteristics of individual medicines and to examine whether rational standards allow the most appropriate medicines to be chosen. Participants diagnosed with lumbar spinal stenosis (LSS) were assessed for QOL and ADL based on the Roland-Morris Disability Questionnaire, JOA score, VAS, and the presence of intermittent claudication (IC). Four medicines--beraprost sodium, ethyl icosapentate (EPA), sarpogrelate hydrochloride, and limaprost alfadex (PGE1)--were prescribed in a random manner. These four medicines were assessed independently in four studies using the same study design and size in each case. Using the NMatrix, the characteristics of the four medicines and the results of mutual comparisons could be displayed concisely and clearly in one matrix based on significance levels. This work involved analyzing pooled data from the four studies. All four medicines improved IC--one of the characteristic symptoms of LSS--by 12 weeks after administration. PGE1 required more time than the other medicines to affect IC. EPA appeared to almost significantly ameliorate some items at every point, though the evidence was insufficient. The NMatrix concisely and clearly displays the characteristics of "medicines with similar effects" for the treatment of lumbar spinal stenosis, and can help physicians to choose the optimal medicine based on rational criteria for individual patients, according to their symptoms and progress.

Design of a concise Féry-prism hyperspectral imaging system based on multi-configuration

NASA Astrophysics Data System (ADS)

Dong, Wei; Nie, Yun-feng; Zhou, Jin-song

2013-08-01

In order to meet the needs of space borne and airborne hyperspectral imaging system for light weight, simplification and high spatial resolution, a novel design of Féry-prism hyperspectral imaging system based on Zemax multi-configuration method is presented. The novel structure is well arranged by analyzing optical monochromatic aberrations theoretically, and the optical structure of this design is concise. The fundamental of this design is Offner relay configuration, whereas the secondary mirror is replaced by Féry-prism with curved surfaces and a reflective front face. By reflection, the light beam passes through the Féry-prism twice, which promotes spectral resolution and enhances image quality at the same time. The result shows that the system can achieve light weight and simplification, compared to other hyperspectral imaging systems. Composed of merely two spherical mirrors and one achromatized Féry-prism to perform both dispersion and imaging functions, this structure is concise and compact. The average spectral resolution is 6.2nm; The MTFs for 0.45~1.00um spectral range are greater than 0.75, RMSs are less than 2.4um; The maximal smile is less than 10% pixel, while the keystones is less than 2.8% pixel; image quality approximates the diffraction limit. The design result shows that hyperspectral imaging system with one modified Féry-prism substituting the secondary mirror of Offner relay configuration is feasible from the perspective of both theory and practice, and possesses the merits of simple structure, convenient optical alignment, and good image quality, high resolution in space and spectra, adjustable dispersive nonlinearity. The system satisfies the requirements of airborne or space borne hyperspectral imaging system.

U.S.-China Relations: The China Council of the Asia Society. A Medial Source Guide, Issues for the '80s.

ERIC Educational Resources Information Center

Council on International and Public Affairs, New York, NY.

Concise, authoritative background information on U.S.-China relations is provided for journalists in this guide, one of a series dealing with topics of interest to the U.S. media. The guide begins with a chronology of U.S.-China relations from 1979 to 1982. The texts of documents on U.S.-China relations are then presented. These include the…

Promoting International Energy Security: Volume 4, The Gulf of Guinea

DTIC Science & Technology

2012-01-01

Politicians, both federal and state, routinely 2 For a recent and concise review of stability in Nigeria, see Nigeria: Assessing Risks to Stability (Lewis...Export Customer for ATR 42MP,” Defense News, December 10, 2009. Lewis, Peter M., Nigeria: Assessing Risks to Stability, Washington, D.C.: Center for...especially the risks that U.S.-provided military capabilities might be applied to local civilian populations. While there are signs of improved governance

A Thermal Dehydrogenative Diels–Alder Reaction of Styrenes for the Concise Synthesis of Functionalized Naphthalenes

PubMed Central

Kocsis, Laura S.; Benedetti, Erica

2012-01-01

Functionalized naphthalenes are valuable building blocks in many important areas. A microwave-assisted, intramolecular dehydrogenative Diels-Alder reaction of styrenyl derivatives to provide cyclopenta[b]naphthalene substructures not previously accessible using existing synthetic methods is described. The synthetic utility of these uniquely functionalized naphthalenes was demonstrated by a single-step conversion of one of these cycloadducts to a fluorophore bearing a structural resemblance to Prodan. PMID:22913473

A thermal dehydrogenative Diels-Alder reaction of styrenes for the concise synthesis of functionalized naphthalenes.

PubMed

Kocsis, Laura S; Benedetti, Erica; Brummond, Kay M

2012-09-07

Functionalized naphthalenes are valuable building blocks in many important areas. A microwave-assisted, intramolecular dehydrogenative Diels-Alder reaction of styrenyl derivatives to provide cyclopenta[b]naphthalene substructures not previously accessible using existing synthetic methods is described. The synthetic utility of these uniquely functionalized naphthalenes was demonstrated by a single-step conversion of one of these cycloadducts to a fluorophore bearing a structural resemblance to Prodan.

An Overview of Epidemic Typhus in the World and Iran during the 19th and 20th Centuries.

PubMed

Azizi, Mohammad Hossein; Bahadori, Moslem; Azizi, Farzaneh

2016-10-01

The present article provides a concise historical review on classical epidemic typhus (exanthemata typhus) in the world as well its outbreaks in Iran mainly during the 19th and 20th centuries. Typhus is still a potential public health threat under certain conditions, despite the fact that nowadays, efficient antibiotics are accessible and sanitary conditions which lead to typhus outbreaks have improved significantly.

Meaning in animal and human communication.

PubMed

Scott-Phillips, Thomas C

2015-05-01

What is meaning? While traditionally the domain of philosophy and linguistics, this question, and others related to it, is critical for cognitive and comparative approaches to communication. This short essay provides a concise and accessible description of how the term meaning can and should be used, how it relates to 'intentional communication', and what would constitute good evidence of meaning in animal communication, in the sense that is relevant for comparisons with human language.

MARRVEL: Integration of Human and Model Organism Genetic Resources to Facilitate Functional Annotation of the Human Genome.

PubMed

Wang, Julia; Al-Ouran, Rami; Hu, Yanhui; Kim, Seon-Young; Wan, Ying-Wooi; Wangler, Michael F; Yamamoto, Shinya; Chao, Hsiao-Tuan; Comjean, Aram; Mohr, Stephanie E; Perrimon, Norbert; Liu, Zhandong; Bellen, Hugo J

2017-06-01

One major challenge encountered with interpreting human genetic variants is the limited understanding of the functional impact of genetic alterations on biological processes. Furthermore, there remains an unmet demand for an efficient survey of the wealth of information on human homologs in model organisms across numerous databases. To efficiently assess the large volume of publically available information, it is important to provide a concise summary of the most relevant information in a rapid user-friendly format. To this end, we created MARRVEL (model organism aggregated resources for rare variant exploration). MARRVEL is a publicly available website that integrates information from six human genetic databases and seven model organism databases. For any given variant or gene, MARRVEL displays information from OMIM, ExAC, ClinVar, Geno2MP, DGV, and DECIPHER. Importantly, it curates model organism-specific databases to concurrently display a concise summary regarding the human gene homologs in budding and fission yeast, worm, fly, fish, mouse, and rat on a single webpage. Experiment-based information on tissue expression, protein subcellular localization, biological process, and molecular function for the human gene and homologs in the seven model organisms are arranged into a concise output. Hence, rather than visiting multiple separate databases for variant and gene analysis, users can obtain important information by searching once through MARRVEL. Altogether, MARRVEL dramatically improves efficiency and accessibility to data collection and facilitates analysis of human genes and variants by cross-disciplinary integration of 18 million records available in public databases to facilitate clinical diagnosis and basic research. Copyright © 2017 American Society of Human Genetics. Published by Elsevier Inc. All rights reserved.

Portal vein thrombosis: a clinician-oriented and practical review.

PubMed

Handa, Pankaj; Crowther, Mark; Douketis, James D

2014-07-01

With advances in modern imaging techniques, portal vein thrombosis (PVT) is being increasingly diagnosed. It has a wide ranging clinical spectrum from being an asymptomatic state to a potentially life-threatening situation. It is not unusual to find it as an incidental finding in the abdominal imagings done for other reasons. It is commonly associated with cirrhosis and abdominal malignancies and also has a strong association with prothrombotic disorders. It is often difficult for the clinicians to decide whether PVT is acute or chronic. This poses great challenges to its management strategies that include anticoagulants, thrombolysis, and surgical options. Timely diagnosis and appropriate management have great bearings on its outcomes of morbidity and mortality. In this clinician-oriented review, we have provided a concise review of clinical aspects of PVT and discussed various management strategies while addressing the common questions that come to a physician's mind dealing with such a patient. © The Author(s) 2013.

Bringing new life to damaged bone: the importance of angiogenesis in bone repair and regeneration.

PubMed

Stegen, Steve; van Gastel, Nick; Carmeliet, Geert

2015-01-01

Bone has the unique capacity to heal without the formation of a fibrous scar, likely because several of the cellular and molecular processes governing bone healing recapitulate the events during skeletal development. A critical component in bone healing is the timely appearance of blood vessels in the fracture callus. Angiogenesis, the formation of new blood vessels from pre-existing ones, is stimulated after fracture by the local production of numerous angiogenic growth factors. The fracture vasculature not only supplies oxygen and nutrients, but also stem cells able to differentiate into osteoblasts and in a later phase also the ions necessary for mineralization. This review provides a concise report of the regulation of angiogenesis by bone cells, its importance during bone healing and its possible therapeutic applications in bone tissue engineering. This article is part of a Special Issue entitled "Stem Cells and Bone". Copyright © 2014 Elsevier Inc. All rights reserved.

Concise Review: Parthenote Stem Cells for Regenerative Medicine: Genetic, Epigenetic, and Developmental Features

PubMed Central

Daughtry, Brittany

2014-01-01

Embryonic stem cells (ESCs) have the potential to provide unlimited cells and tissues for regenerative medicine. ESCs derived from fertilized embryos, however, will most likely be rejected by a patient’s immune system unless appropriately immunomatched. Pluripotent stem cells (PSCs) genetically identical to a patient can now be established by reprogramming of somatic cells. However, practical applications of PSCs for personalized therapies are projected to be unfeasible because of the enormous cost and time required to produce clinical-grade cells for each patient. ESCs derived from parthenogenetic embryos (pESCs) that are homozygous for human leukocyte antigens may serve as an attractive alternative for immunomatched therapies for a large population of patients. In this study, we describe the biology and genetic nature of mammalian parthenogenesis and review potential advantages and limitations of pESCs for cell-based therapies. PMID:24443005

Benefit sharing: it's time for a definition.

PubMed

Schroeder, D

2007-04-01

Benefit sharing has been a recurrent theme in international debates for the past two decades. However, despite its prominence in law, medical ethics and political philosophy, the concept has never been satisfactorily defined. In this conceptual paper, a definition that combines current legal guidelines with input from ethics debates is developed. Philosophers like boxes; protective casings into which they can put concisely-defined concepts. Autonomy is the human capacity for self-determination; beneficence denotes the virtue of good deeds, coercion is the intentional threat of harm and so on. What about benefit sharing? Does the concept have a box and are the contents clearly defined? The answer to this question has to be no. The concept of benefit sharing is almost unique in that various disciplines use it regularly without precise definitions. In this article, a definition for benefit sharing is provided, to eliminate unnecessary ambiguity.

Interdisciplinary group approach to occupational safety and health administration standard: reductions in cost and duplication of effort.

PubMed

Canola, T; Kirkis, E J; Meckes, P F; Pitts, S B

1994-06-01

After the December 1991 publication of the Occupational Safety and Health Administration standard, "Occupational Exposure to Bloodborne Pathogens; Final Rule," medical facilities in the United States were challenged to meet the mandates of this standard with massive training in a relatively short time. An interdisciplinary task force composed of representative members of a major health maintenance organization was charged with the task of developing a training plan for 11 Southern California medical centers and their 42 satellite medical offices. The task force ultimately developed, refined, and distributed a Trainer Guidebook that could be used by a variety of disciplines. This guidebook provided a method by which the information could be disseminated concisely, thoroughly, and promptly. The processes used in this project can be applied to other health care educational situations. The purpose of this article is to share these processes.

Current challenges in monitoring, discrimination, and management of induced seismicity related to underground industrial activities: A European perspective

NASA Astrophysics Data System (ADS)

Grigoli, Francesco; Cesca, Simone; Priolo, Enrico; Rinaldi, Antonio Pio; Clinton, John F.; Stabile, Tony A.; Dost, Bernard; Fernandez, Mariano Garcia; Wiemer, Stefan; Dahm, Torsten

2017-06-01

Due to the deep socioeconomic implications, induced seismicity is a timely and increasingly relevant topic of interest for the general public. Cases of induced seismicity have a global distribution and involve a large number of industrial operations, with many documented cases from as far back to the beginning of the twentieth century. However, the sparse and fragmented documentation available makes it difficult to have a clear picture on our understanding of the physical phenomenon and consequently in our ability to mitigate the risk associated with induced seismicity. This review presents a unified and concise summary of the still open questions related to monitoring, discrimination, and management of induced seismicity in the European context and, when possible, provides potential answers. We further discuss selected critical European cases of induced seismicity, which led to the suspension or reduction of the related industrial activities.

Reinforcing the foundations of ornithological nomenclature: Filling the gaps in Sherborn's and Richmond's historical legacy of bibliographic exploration.

PubMed

Dickinson, Edward C

2016-01-01

Due to its public popularity, ornithology has a huge corpus of scientific publication for a relatively small number of species. Although there are global checklists of currently recognised taxa, there has been only limited, mainly individual, effort to build a nomenclatural database that the science of ornithology deserves. This is especially true in relation to concise synonymies. With the arrival of ZooBank and the Biodiversity Heritage Library, the time has come to develop synonymies and to add fuller bibliographic detail to databases. The preparation for both began at the start of the 20(th) century with extensive work by Sherborn and Richmond. I discuss their legacy, offer notes on significant work since then, and provide suggestions for what remains to be done. To make solid the foundations for ornithological nomenclature and taxonomy, especially for synonymies, ornithologists will need to collaborate much more and contribute to the digital infrastructure.

Cancer concepts and principles: primer for the interventional oncologist-part I.

PubMed

Hickey, Ryan; Vouche, Michael; Sze, Daniel Y; Hohlastos, Elias; Collins, Jeremy; Schirmang, Todd; Memon, Khairuddin; Ryu, Robert K; Sato, Kent; Chen, Richard; Gupta, Ramona; Resnick, Scott; Carr, James; Chrisman, Howard B; Nemcek, Albert A; Vogelzang, Robert L; Lewandowski, Robert J; Salem, Riad

2013-08-01

A sophisticated understanding of the rapidly changing field of oncology, including a broad knowledge of oncologic disease and the therapies available to treat them, is fundamental to the interventional radiologist providing oncologic therapies, and is necessary to affirm interventional oncology as one of the four pillars of cancer care alongside medical, surgical, and radiation oncology. The first part of this review intends to provide a concise overview of the fundamentals of oncologic clinical trials, including trial design, methods to assess therapeutic response, common statistical analyses, and the levels of evidence provided by clinical trials. Copyright © 2013 SIR. Published by Elsevier Inc. All rights reserved.

NMR Mapping of Protein Conformational Landscapes using Coordinated Behavior of Chemical Shifts upon Ligand Binding

PubMed Central

Cembran, Alessandro; Kim, Jonggul; Gao, Jiali; Veglia, Gianluigi

2014-01-01

Proteins exist as an ensemble of conformers that are distributed on free energy landscapes resembling folding funnels. While the most stable conformers populate low energy basins, protein function is often carried out through low-populated conformational states that occupy high energy basins. Ligand binding shifts the populations of these states, changing the distribution of these conformers. Understanding how the equilibrium among the states is altered upon ligand binding, interaction with other binding partners, and/or mutations and post-translational modifications is of critical importance for explaining allosteric signaling in proteins. Here, we propose a statistical analysis of the chemical shifts (CONCISE, COordiNated ChemIcal Shifts bEhavior) for the interpretation of protein conformational equilibria following linear trajectories of NMR chemical shifts. CONCISE enables one to quantitatively measure the population shifts associated with ligand titrations and estimate the degree of collectiveness of the protein residues’ response to ligand binding, giving a concise view of the structural transitions. The combination of CONCISE with thermocalorimetric and kinetic data allows one to depict a protein’s approximate conformational energy landscape. We tested this method with the catalytic subunit of cAMP-dependent protein kinase A, a ubiquitous enzyme that undergoes conformational transitions upon both nucleotide and pseudo-substrate binding. When complemented with chemical shift covariance analysis (CHESCA), this new method offers both collective response and residue-specific correlations for ligand binding to proteins. PMID:24604024

Efficient Type Representation in TAL

NASA Technical Reports Server (NTRS)

Chen, Juan

2009-01-01

Certifying compilers generate proofs for low-level code that guarantee safety properties of the code. Type information is an essential part of safety proofs. But the size of type information remains a concern for certifying compilers in practice. This paper demonstrates type representation techniques in a large-scale compiler that achieves both concise type information and efficient type checking. In our 200,000-line certifying compiler, the size of type information is about 36% of the size of pure code and data for our benchmarks, the best result to the best of our knowledge. The type checking time is about 2% of the compilation time.

Concise calculation of the scaling function, exponents, and probability functional of the Edwards-Wilkinson equation with correlated noise

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yu, Y.; Pang, N.; Halpin-Healy, T.

1994-12-01

The linear Langevin equation proposed by Edwards and Wilkinson [Proc. R. Soc. London A 381, 17 (1982)] is solved in closed form for noise of arbitrary space and time correlation. Furthermore, the temporal development of the full probability functional describing the height fluctuations is derived exactly, exhibiting an interesting evolution between two distinct Gaussian forms. We determine explicitly the dynamic scaling function for the interfacial width for any given initial condition, isolate the early-time behavior, and discover an invariance that was unsuspected in this problem of arbitrary spatiotemporal noise.

Atmospheric Effects of Subsonic Aircraft: Interim Assessment Report of the Advanced Subsonic Technology Program

NASA Technical Reports Server (NTRS)

Friedl, Randall R. (Editor)

1997-01-01

This first interim assessment of the subsonic assessment (SASS) project attempts to summarize concisely the status of our knowledge concerning the impacts of present and future subsonic aircraft fleets. It also highlights the major areas of scientific uncertainty, through review of existing data bases and model-based sensitivity studies. In view of the need for substantial improvements in both model formulations and experimental databases, this interim assessment cannot provide confident numerical predictions of aviation impacts. However, a number of quantitative estimates are presented, which provide some guidance to policy makers.

Facesheet Wrinkling in Sandwich Structures

NASA Technical Reports Server (NTRS)

Ley, Robert P.; Lin, Weichuan; Mbanefo, Uy

1999-01-01

The purpose of this paper is to provide a concise summary of the state-of-the-art for the analysis of the facesheet wrinkling mode of failure in sandwich structures. This document is not an exhaustive review of the published research related to facesheet wrinkling. Instead, a smaller number of key papers are reviewed in order to provide designers and analysts with a working understanding of the state-of-the-art. Designers and analysts should use this survey to guide their judgement when deciding which one of a wide variety of available facesheet wrinkling design formulas is applicable to a specific design problem.

Concise and Efficient Fluorescent Probe via an Intromolecular Charge Transfer for the Chemical Warfare Agent Mimic Diethylchlorophosphate Vapor Detection.

PubMed

Yao, Junjun; Fu, Yanyan; Xu, Wei; Fan, Tianchi; Gao, Yixun; He, Qingguo; Zhu, Defeng; Cao, Huimin; Cheng, Jiangong

2016-02-16

Sarin, used as chemical warfare agents (CWAs) for terrorist attacks, can induce a number of virulent effects. Therefore, countermeasures which could realize robust and convenient detection of sarin are in exigent need. A concise charge-transfer colorimetric and fluorescent probe (4-(6-(tert-butyl)pyridine-2-yl)-N,N-diphenylaniline, TBPY-TPA) that could be capable of real-time and on-site monitoring of DCP vapor was reported in this contribution. Upon contact with DCP, the emission band red-shifted from 410 to 522 nm upon exposure to DCP vapor. And the quenching rate of TBPY-TPA reached up to 98% within 25 s. Chemical substances such as acetic acid (HAc), dimethyl methylphosphonate (DMMP), pinacolyl methylphosphonate (PAMP), and triethyl phosphate (TEP) do not interfere with the detection. A detection limit for DCP down to 2.6 ppb level is remarkably achieved which is below the Immediately Dangerous to Life or Health concentration. NMR data suggested that a transformation of the pyridine group into pyridinium salt via a cascade reaction is responsible for the sensing process which induced the dramatic fluorescent red shift. All of these data suggest TBPY-TPA is a promising fluorescent sensor for a rapid, simple, and low-cost method for DCP detection, which could be easy to prepare as a portable chemosensor kit for its practical application in real-time and on-site monitoring.

ARM Climate Research Facility Quarterly Ingest Status Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Koontz, A.; Sivaraman, C.

2016-10-01

The purpose of this report is to provide a concise status update for ingests maintained by the Atmospheric Radiation Measurement (ARM) Climate Research Facility. The report is divided into the following sections: (1) new ingests for which development has begun, (2) progress on existing ingests, (3) future ingests that have been recently approved, (4) other work that leads to an ingest, and (5) top requested ingests from the ARM Data Archive. New information is highlighted in blue text.

ARM Climate Research Facility Quarterly Ingest Status Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Koontz, A.; Sivaraman, C.

2016-07-01

The purpose of this report is to provide a concise status update for ingests maintained by the Atmospheric Radiation Measurement (ARM) Climate Research Facility. The report is divided into the following sections: (1) new ingests for which development has begun, (2) progress on existing ingests, (3) future ingests that have been recently approved, (4) other work that leads to an ingest, and (5) top requested ingests from the ARM Data Archive. New information is highlighted in blue text.

The "Bermuda triangle" of neonatal neurology: cerebral palsy, neonatal encephalopathy, and intrapartum asphyxia.

PubMed

Shevell, Michael I

2004-03-01

The terms "cerebral palsy," "neonatal encephalopathy," and "intrapartum asphyxia" are frequently used in pediatric neurology. This article presents concise, verifiable definitions for each of these entities based on our current understanding and formulates the nature of the interrelationships between them. The aim is to provide a level of clarity that will enhance diagnostic and pathogenetic precision and minimize conceptual misunderstanding. This should aid future therapeutic and research efforts in this important area.

Robot Control Based On Spatial-Operator Algebra

NASA Technical Reports Server (NTRS)

Rodriguez, Guillermo; Kreutz, Kenneth K.; Jain, Abhinandan

1992-01-01

Method for mathematical modeling and control of robotic manipulators based on spatial-operator algebra providing concise representation and simple, high-level theoretical frame-work for solution of kinematical and dynamical problems involving complicated temporal and spatial relationships. Recursive algorithms derived immediately from abstract spatial-operator expressions by inspection. Transition from abstract formulation through abstract solution to detailed implementation of specific algorithms to compute solution greatly simplified. Complicated dynamical problems like two cooperating robot arms solved more easily.

Seismic Parameters of Mining-Induced Aftershock Sequences for Re-entry Protocol Development

NASA Astrophysics Data System (ADS)

Vallejos, Javier A.; Estay, Rodrigo A.

2018-03-01

A common characteristic of deep mines in hard rock is induced seismicity. This results from stress changes and rock failure around mining excavations. Following large seismic events, there is an increase in the levels of seismicity, which gradually decay with time. Restricting access to areas of a mine for enough time to allow this decay of seismic events is the main approach in re-entry strategies. The statistical properties of aftershock sequences can be studied with three scaling relations: (1) Gutenberg-Richter frequency magnitude, (2) the modified Omori's law (MOL) for the temporal decay, and (3) Båth's law for the magnitude of the largest aftershock. In this paper, these three scaling relations, in addition to the stochastic Reasenberg-Jones model are applied to study the characteristic parameters of 11 large magnitude mining-induced aftershock sequences in four mines in Ontario, Canada. To provide guidelines for re-entry protocol development, the dependence of the scaling relation parameters on the magnitude of the main event are studied. Some relations between the parameters and the magnitude of the main event are found. Using these relationships and the scaling relations, a space-time-magnitude re-entry protocol is developed. These findings provide a first approximation to concise and well-justified guidelines for re-entry protocol development applicable to the range of mining conditions found in Ontario, Canada.

Finite time synchronization of memristor-based Cohen-Grossberg neural networks with mixed delays.

PubMed

Chen, Chuan; Li, Lixiang; Peng, Haipeng; Yang, Yixian

2017-01-01

Finite time synchronization, which means synchronization can be achieved in a settling time, is desirable in some practical applications. However, most of the published results on finite time synchronization don't include delays or only include discrete delays. In view of the fact that distributed delays inevitably exist in neural networks, this paper aims to investigate the finite time synchronization of memristor-based Cohen-Grossberg neural networks (MCGNNs) with both discrete delay and distributed delay (mixed delays). By means of a simple feedback controller and novel finite time synchronization analysis methods, several new criteria are derived to ensure the finite time synchronization of MCGNNs with mixed delays. The obtained criteria are very concise and easy to verify. Numerical simulations are presented to demonstrate the effectiveness of our theoretical results.

Concise Redox Deracemization of Secondary and Tertiary Amines with a Tetrahydroisoquinoline Core via a Nonenzymatic Process.

PubMed

Ji, Yue; Shi, Lei; Chen, Mu-Wang; Feng, Guang-Shou; Zhou, Yong-Gui

2015-08-26

A concise deracemization of racemic secondary and tertiary amines with a tetrahydroisoquinoline core has been successfully realized by orchestrating a redox process consisted of N-bromosuccinimide oxidation and iridum-catalyzed asymmetric hydrogenation. This compatible redox combination enables one-pot, single-operation deracemization to generate chiral 1-substituted 1,2,3,4-tetrahydroisoquinolines with up to 98% ee in 93% yield, offering a simple and scalable synthetic technique for chiral amines directly from racemic starting materials.

Concise chemical synthesis of a tetrasaccharide repeating unit of the O-antigen of Hafnia alvei 10457.

PubMed

Kumar, Rishi; Maulik, Prakas R; Misra, Anup Kumar

2008-08-01

Concise chemical synthesis of a tetrasaccharide repeating unit of the O-antigen of Hafnia alvei 10457 is reported. Construction of the tetrasaccharide as its 4-methoxyphenyl glycoside was achieved by condensation of less abundant monosaccharide units such as, D-galactofuranose, N-acetyl-D-galactosamine and N-acetylneuraminic acid. The synthetic strategy consists of the preparation of suitably protected required monosaccharide intermediates from the commercially available reducing sugars and high yielding glycosylation reactions.

Incremental classification learning for anomaly detection in medical images

NASA Astrophysics Data System (ADS)

Giritharan, Balathasan; Yuan, Xiaohui; Liu, Jianguo

2009-02-01

Computer-aided diagnosis usually screens thousands of instances to find only a few positive cases that indicate probable presence of disease.The amount of patient data increases consistently all the time. In diagnosis of new instances, disagreement occurs between a CAD system and physicians, which suggests inaccurate classifiers. Intuitively, misclassified instances and the previously acquired data should be used to retrain the classifier. This, however, is very time consuming and, in some cases where dataset is too large, becomes infeasible. In addition, among the patient data, only a small percentile shows positive sign, which is known as imbalanced data.We present an incremental Support Vector Machines(SVM) as a solution for the class imbalance problem in classification of anomaly in medical images. The support vectors provide a concise representation of the distribution of the training data. Here we use bootstrapping to identify potential candidate support vectors for future iterations. Experiments were conducted using images from endoscopy videos, and the sensitivity and specificity were close to that of SVM trained using all samples available at a given incremental step with significantly improved efficiency in training the classifier.

Users Manual for the Geospatial Stream Flow Model (GeoSFM)

USGS Publications Warehouse

Artan, Guleid A.; Asante, Kwabena; Smith, Jodie; Pervez, Md Shahriar; Entenmann, Debbie; Verdin, James P.; Rowland, James

2008-01-01

The monitoring of wide-area hydrologic events requires the manipulation of large amounts of geospatial and time series data into concise information products that characterize the location and magnitude of the event. To perform these manipulations, scientists at the U.S. Geological Survey Center for Earth Resources Observation and Science (EROS), with the cooperation of the U.S. Agency for International Development, Office of Foreign Disaster Assistance (USAID/OFDA), have implemented a hydrologic modeling system. The system includes a data assimilation component to generate data for a Geospatial Stream Flow Model (GeoSFM) that can be run operationally to identify and map wide-area streamflow anomalies. GeoSFM integrates a geographical information system (GIS) for geospatial preprocessing and postprocessing tasks and hydrologic modeling routines implemented as dynamically linked libraries (DLLs) for time series manipulations. Model results include maps that depicting the status of streamflow and soil water conditions. This Users Manual provides step-by-step instructions for running the model and for downloading and processing the input data required for initial model parameterization and daily operation.

Emergencies in Orthodontics. Part 2: Management of Removable Appliances, Functional Appliances and other Adjuncts to Orthodontic Treatment.

PubMed

Dowsing, Paul; Murray, Alison; Sandler, Jonathan

2015-04-01

In the second of two papers, management of orthodontic emergencies involving appliances other than Fixed appliances will be detailed. Problems relating to removable appliances, as well as other orthodontic adjuncts, will be discussed. Unfortunately, orthodontic appliance breakage does occur, despite the clinicians giving clear and concise instructions to the patients and their parents at fitting. If general dental practitioners have a practical knowledge of how to diagnose problems and to provide appropriate advice or timely 'emergency' treatment, this will significantly reduce the inconvenience for all parties concerned. It should also ensure that treatment progresses in the most efficient and comfortable manner for their patients. In specific situations the early, accurate identification of the problem and instigation of its appropriate management can avoid more serious consequences. Clinical Relevance: Appropriate handling of an orthodontic 'emergency' by the dentist can, on many occasions, provide immediate relief to the patient. This will, in turn, allow treatment to continue in the right direction, thus allowing more efficient and effective use of valuable resources.

Grouping like catchments: A novel means to compare 40+ watersheds in the Northeastern U.S.

NASA Astrophysics Data System (ADS)

Shaw, S. B.; Walter, M.; Marjerison, R. D.

2008-12-01

One difficulty in understanding the effect of multi-scale patterns in watersheds comes from finding a concise way to identify and compare features across many basins. Comparing raw data (i.e. discharge time series) requires one to account for highly variable climate drivers while extracting meaningful metrics from the data series. Comparing model parameters imposes model assumptions that may obscure fundamental differences, potentially making it an exercise in comparing calibration factors. As a possible middle ground, we have found that the probability of a given basin-wide runoff response can be predicted by combining rainfall frequency with 1. a curve establishing a relationship between basin storage and base flow and 2. the baseflow flow-duration curve. In addition to providing a means to predict runoff, these curves succinctly present empirical runoff-response information, allowing ready graphical comparison of multiple watersheds. From 40+ watersheds throughout the Northeastern U.S., we demonstrate the potential to group watersheds and identify critical hydrologic features, providing particular insight into the influence of land use patterns as well as basin scale.

The Revisited Classification of GN in SLE at 10 Years: Time to Re-Evaluate Histopathologic Lesions

PubMed Central

Alpers, Charles E.; Cook, H. Terence; Ferrario, Franco; Fogo, Agnes B.; Haas, Mark; Joh, Kensuke; Noël, Laure-Hélène; Seshan, Surya V.; Bruijn, Jan A.; Bajema, Ingeborg M.

2015-01-01

Over 10 years have passed since the latest revision of the histopathologic classification of lupus nephritis. This revision was a significant improvement compared with the previous version, mainly because of clearer and more concise definitions and the elimination of mixed subclasses. Despite these improvements, there are still some difficulties in the classification for lupus nephritis, many of which are in the definitions provided. In this review, we focus on the difficulties surrounding the evaluation of classes III and IV lesions, particularly the definitions of endocapillary and extracapillary proliferation, the use of the terms endocapillary proliferation and hypercellularity, the clinical relevance of segmental and global subdivision in class IV, and the value of distinguishing lesions that indicate activity and chronicity. Vascular and tubulointerstitial lesions are also discussed. Furthermore, we give an overview of the history of the classification to provide background on the origin and development of the definitions in lupus nephritis. The issues raised in this review as well as the suggestions for improvements may assist with a revision of the lupus nephritis classification in the near future. PMID:26152271

A short note on the use of the red-black tree in Cartesian adaptive mesh refinement algorithms

NASA Astrophysics Data System (ADS)

Hasbestan, Jaber J.; Senocak, Inanc

2017-12-01

Mesh adaptivity is an indispensable capability to tackle multiphysics problems with large disparity in time and length scales. With the availability of powerful supercomputers, there is a pressing need to extend time-proven computational techniques to extreme-scale problems. Cartesian adaptive mesh refinement (AMR) is one such method that enables simulation of multiscale, multiphysics problems. AMR is based on construction of octrees. Originally, an explicit tree data structure was used to generate and manipulate an adaptive Cartesian mesh. At least eight pointers are required in an explicit approach to construct an octree. Parent-child relationships are then used to traverse the tree. An explicit octree, however, is expensive in terms of memory usage and the time it takes to traverse the tree to access a specific node. For these reasons, implicit pointerless methods have been pioneered within the computer graphics community, motivated by applications requiring interactivity and realistic three dimensional visualization. Lewiner et al. [1] provides a concise review of pointerless approaches to generate an octree. Use of a hash table and Z-order curve are two key concepts in pointerless methods that we briefly discuss next.

Leptospirosis.

PubMed

Slack, Andrew

2010-07-01

This article forms part of our travel medicine series for 2010, providing a summary of prevention strategies and vaccination for infections that may be acquired by travellers. The series aims to provide practical strategies to assist general practitioners in giving travel advice, as a synthesis of multiple information sources which must otherwise be consulted. Leptospirosis is one of the many diseases responsible for undifferentiated febrile illness, especially in the tropical regions or in the returned traveller. It is a disease of global importance, and knowledge in the disease is continually developing. The aim of this article is to provide clinicians with a concise review of the epidemiology, pathophysiology, clinical features, diagnosis, management and prevention of leptospirosis. Leptospirosis should be included in the broad differential diagnosis of febrile illness. The clinical manifestations of the disease vary from mild, nonspecific illness through to severe illness resulting in acute renal failure, hepatic failure and pulmonary haemorrhage. Diagnosis is dependant on accurate prediction of the time of infection: culture, polymerase chain reaction and serology may be used to confirm the diagnosis. Management is centred on prompt antibiotic therapy using doxycycline or intravenous penicillin G or intravenous ceftriaxone/cefotaxime. Prevention of leptospirosis revolves around the 'cover-wash-clean up' strategy.

Time-dependent structural transformation analysis to high-level Petri net model with active state transition diagram

PubMed Central

2010-01-01

Background With an accumulation of in silico data obtained by simulating large-scale biological networks, a new interest of research is emerging for elucidating how living organism functions over time in cells. Investigating the dynamic features of current computational models promises a deeper understanding of complex cellular processes. This leads us to develop a method that utilizes structural properties of the model over all simulation time steps. Further, user-friendly overviews of dynamic behaviors can be considered to provide a great help in understanding the variations of system mechanisms. Results We propose a novel method for constructing and analyzing a so-called active state transition diagram (ASTD) by using time-course simulation data of a high-level Petri net. Our method includes two new algorithms. The first algorithm extracts a series of subnets (called temporal subnets) reflecting biological components contributing to the dynamics, while retaining positive mathematical qualities. The second one creates an ASTD composed of unique temporal subnets. ASTD provides users with concise information allowing them to grasp and trace how a key regulatory subnet and/or a network changes with time. The applicability of our method is demonstrated by the analysis of the underlying model for circadian rhythms in Drosophila. Conclusions Building ASTD is a useful means to convert a hybrid model dealing with discrete, continuous and more complicated events to finite time-dependent states. Based on ASTD, various analytical approaches can be applied to obtain new insights into not only systematic mechanisms but also dynamics. PMID:20356411

Disaster management mobile protocols: a technology that will save lives.

PubMed

Williamson, Hope M

2011-01-01

Although training and education have long been accepted as integral to disaster preparedness, many currently taught practices are neither evidence based nor standardized. The need for effective evidence-based disaster education for healthcare workers at all levels in the multidisciplinary medical response to major events has been designated by the disaster response community as a high priority. This article describes a disaster management mobile application of systematic evidence-based practice. The application is interactive and comprises portable principles, algorithms, and emergency protocols that are agile, concise, comprehensive, and response relevant to all healthcare workers. Early recognition through clinical assessment versus laboratory and diagnostic procedures in chemical, biological, radiological, and nuclear (CBRNE) exposures grounded in an evidence-based skill set is especially important. During the immediate threat, the clinical diagnosis can get frustrating because CBRNE casualties can mimic everyday healthcare illnesses and initially present with nonspecific respiratory or flu-like symptoms. As there is minimal time in a catastrophic event for the medical provider to make accurate decisions, access to accurate, timely, and comprehensive information in these situations is critical. The CBRNE mobile application is intended to provide a credible source for treatment and management of numerous patients in an often intimidating environment with scarce resources and overwhelming tasks.

Assessing composition and structure of soft biphasic media from Kelvin-Voigt fractional derivative model parameters

NASA Astrophysics Data System (ADS)

Zhang, Hongmei; Wang, Yue; Fatemi, Mostafa; Insana, Michael F.

2017-03-01

Kelvin-Voigt fractional derivative (KVFD) model parameters have been used to describe viscoelastic properties of soft tissues. However, translating model parameters into a concise set of intrinsic mechanical properties related to tissue composition and structure remains challenging. This paper begins by exploring these relationships using a biphasic emulsion materials with known composition. Mechanical properties are measured by analyzing data from two indentation techniques—ramp-stress relaxation and load-unload hysteresis tests. Material composition is predictably correlated with viscoelastic model parameters. Model parameters estimated from the tests reveal that elastic modulus E 0 closely approximates the shear modulus for pure gelatin. Fractional-order parameter α and time constant τ vary monotonically with the volume fraction of the material’s fluid component. α characterizes medium fluidity and the rate of energy dissipation, and τ is a viscous time constant. Numerical simulations suggest that the viscous coefficient η is proportional to the energy lost during quasi-static force-displacement cycles, E A . The slope of E A versus η is determined by α and the applied indentation ramp time T r. Experimental measurements from phantom and ex vivo liver data show close agreement with theoretical predictions of the η -{{E}A} relation. The relative error is less than 20% for emulsions 22% for liver. We find that KVFD model parameters form a concise features space for biphasic medium characterization that described time-varying mechanical properties. The experimental work was carried out at the Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA. Methodological development, including numerical simulation and all data analysis, were carried out at the school of Life Science and Technology, Xi’an JiaoTong University, 710049, China.

An Optimized Integrator Windup Protection Technique Applied to a Turbofan Engine Control

NASA Technical Reports Server (NTRS)

Watts, Stephen R.; Garg, Sanjay

1995-01-01

This paper introduces a new technique for providing memoryless integrator windup protection which utilizes readily available optimization software tools. This integrator windup protection synthesis provides a concise methodology for creating integrator windup protection for each actuation system loop independently while assuring both controller and closed loop system stability. The individual actuation system loops' integrator windup protection can then be combined to provide integrator windup protection for the entire system. This technique is applied to an H(exp infinity) based multivariable control designed for a linear model of an advanced afterburning turbofan engine. The resulting transient characteristics are examined for the integrated system while encountering single and multiple actuation limits.

CTN summary of DSREDS, EDCARS, EDMICS CALS readiness testing. [Computer-aided Acquisition and Logistic Support (CALS) CALS Test Network (CTN), Digital Storage Retrieval Eng. Data System (DSREDS), Eng. Data Computer Assisted Retrieval System (EDCARS), Eng. Data Management Information and Control System (EDMICS)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mitschkowetz, N.; Vickers, D.L.

This report provides a summary of the Computer-aided Acquisition and Logistic Support (CALS) Test Network (CTN) Laboratory Acceptance Test (LAT) and User Application Test (UAT) activities undertaken to evaluate the CALS capabilities being implemented as part of the Department of Defense (DOD) engineering repositories. Although the individual testing activities provided detailed reports for each repository, a synthesis of the results, conclusions, and recommendations is offered to provide a more concise presentation of the issues and the strategies, as viewed from the CTN perspective.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lundstrom, Blake; Chakraborty, Sudipta; Lauss, Georg

This paper presents a concise description of state-of-the-art real-time simulation-based testing methods and demonstrates how they can be used independently and/or in combination as an integrated development and validation approach for smart grid DERs and systems. A three-part case study demonstrating the application of this integrated approach at the different stages of development and validation of a system-integrated smart photovoltaic (PV) inverter is also presented. Laboratory testing results and perspectives from two international research laboratories are included in the case study.

An exact solution for orbit view-periods from a station on a tri-axial ellipsoidal planet

NASA Technical Reports Server (NTRS)

Tang, C. C. H.

1986-01-01

This paper presents the concise exact solution for predicting view-periods to be observed from a masked or unmasked tracking station on a tri-axial ellipsoidal surface. The new exact approach expresses the azimuth and elevation angles of a spacecraft in terms of the station-centered geodetic topocentric coordinates in an elegantly concise manner. A simple and efficient algorithm is developed to avoid costly repetitive computations in searching for neighborhoods near the rise and set times of each satellite orbit for each station. Only one search for each orbit is necessary for each station. Sample results indicate that the use of an assumed spherical earth instead of an 'actual' tri-axial ellipsoidal earth could introduce an error up to a few minutes in a view-period prediction for circular orbits of low or medium altitude. For an elliptical orbit of high eccentricity and long period, the maximum error could be even larger. The analytic treatment and the efficient algorithm are designed for geocentric orbits, but they should be applicable to interplanetary trajectories by an appropriate coordinates transformation at each view-period calculation. This analysis can be accomplished only by not using the classical orbital elements.

An exact solution for orbit view-periods from a station on a tri-axial ellipsoidal planet

NASA Astrophysics Data System (ADS)

Tang, C. C. H.

1986-08-01

This paper presents the concise exact solution for predicting view-periods to be observed from a masked or unmasked tracking station on a tri-axial ellipsoidal surface. The new exact approach expresses the azimuth and elevation angles of a spacecraft in terms of the station-centered geodetic topocentric coordinates in an elegantly concise manner. A simple and efficient algorithm is developed to avoid costly repetitive computations in searching for neighborhoods near the rise and set times of each satellite orbit for each station. Only one search for each orbit is necessary for each station. Sample results indicate that the use of an assumed spherical earth instead of an 'actual' tri-axial ellipsoidal earth could introduce an error up to a few minutes in a view-period prediction for circular orbits of low or medium altitude. For an elliptical orbit of high eccentricity and long period, the maximum error could be even larger. The analytic treatment and the efficient algorithm are designed for geocentric orbits, but they should be applicable to interplanetary trajectories by an appropriate coordinates transformation at each view-period calculation. This analysis can be accomplished only by not using the classical orbital elements.

Fundamentals of Geophysical Fluid Dynamics

NASA Astrophysics Data System (ADS)

McWilliams, James C.

2006-07-01

Earth's atmosphere and oceans exhibit complex patterns of fluid motion over a vast range of space and time scales. These patterns combine to establish the climate in response to solar radiation that is inhomogeneously absorbed by the materials comprising air, water, and land. Spontaneous, energetic variability arises from instabilities in the planetary-scale circulations, appearing in many different forms such as waves, jets, vortices, boundary layers, and turbulence. Geophysical fluid dynamics (GFD) is the science of all these types of fluid motion. This textbook is a concise and accessible introduction to GFD for intermediate to advanced students of the physics, chemistry, and/or biology of Earth's fluid environment. The book was developed from the author's many years of teaching a first-year graduate course at the University of California, Los Angeles. Readers are expected to be familiar with physics and mathematics at the level of general dynamics (mechanics) and partial differential equations. Covers the essential GFD required for atmospheric science and oceanography courses Mathematically rigorous, concise coverage of basic theory and applications to both oceans and atmospheres Author is a world expert; this book is based on the course he has taught for many years Exercises are included, with solutions available to instructors from solutions@cambridge.org

How to succeed in science: a concise guide for young biomedical scientists. Part II: making discoveries

PubMed Central

Yewdell, Jonathan W.

2009-01-01

Making discoveries is the most important part of being a scientist, and also the most fun. Young scientists need to develop the experimental and mental skill sets that enable them to make discoveries, including how to recognize and exploit serendipity when it strikes. Here, I provide practical advice to young scientists on choosing a research topic, designing, performing and interpreting experiments and, last but not least, on maintaining your sanity in the process. PMID:18401347

Adsorption of heavy metal in freeway by asphalt block

NASA Astrophysics Data System (ADS)

Zheng, Chaocheng

2017-08-01

Heavy metals are toxic, persistent, and carcinogenic in freeway. Various techniques are available for the removal of heavy metals from waste water among soils during freeway including ion-exchange, membrane filtration, electrolysis, coagulation, flotation, and adsorption. Among them, bio-sorption processes are widely used for heavy metal and other pollutant removal due to its sustainable, rapid and economic. In this paper, heavy metal removal facilitated by adsorption in plants during freeway was illustrated to provide concise information on exploring the adsorption efficiency.

Microbial ecology laboratory procedures manual NASA/MSFC

NASA Technical Reports Server (NTRS)

Huff, Timothy L.

1990-01-01

An essential part of the efficient operation of any microbiology laboratory involved in sample analysis is a standard procedures manual. The purpose of this manual is to provide concise and well defined instructions on routine technical procedures involving sample analysis and methods for monitoring and maintaining quality control within the laboratory. Of equal importance is the safe operation of the laboratory. This manual outlines detailed procedures to be followed in the microbial ecology laboratory to assure safety, analytical control, and validity of results.

Integrated Science Assessment (ISA) for Lead (Second ...

EPA Pesticide Factsheets

EPA has announced that the Second External Review Draft of the Integrated Science Assessment (ISA) for Lead (Pb) has been made available for independent peer review and public review. This draft ISA represents a concise synthesis and evaluation of the most policy-relevant science and will ultimately provide the scientific bases for EPA’s decision regarding whether the current standards for Pb sufficiently protect public health and the environment. Lead (Pb) is one of six principal (or criteria) pollutants for which EPA has established NAAQS

Systemic lupus erythematosus: Clinical and experimental aspects

DOE Office of Scientific and Technical Information (OSTI.GOV)

Smolen, J.S.

1987-01-01

This text covers questions related to the history, etiology, pathogenesis, clinical aspects and therapy of systematic lupus erythematosus (SLE). Both animal models and human SLE are considered. With regard to basic science, concise information on cellular immunology, autoantibodies, viral aspects and molecular biology in SLE is provided. Clinical topics then deal with medical, dermatologic, neurologic, radiologic, pathologic, and therapeutic aspects. The book not only presents the most recent information on clinical and experimental insights, but also looks at future aspects related to the diagnosis and therapy of SLE.

How to succeed in science: a concise guide for young biomedical scientists. Part II: making discoveries.

PubMed

Yewdell, Jonathan W

2008-06-01

Making discoveries is the most important part of being a scientist, and also the most fun. Young scientists need to develop the experimental and mental skill sets that enable them to make discoveries, including how to recognize and exploit serendipity when it strikes. Here, I provide practical advice to young scientists on choosing a research topic, designing, performing and interpreting experiments and, last but not least, on maintaining your sanity in the process.

Two new species of Erythromelana Townsend, 1919 (Diptera: Tachinidae) from Area de Conservación Guanacaste in northwestern Costa Rica

PubMed Central

Wood, D. Monty; Smith, M. Alex; Hallwachs, Winnie; Janzen, Daniel; Dapkey, Tanya

2016-01-01

Abstract Background We describe two new species in the genus Erythromelana Townsend, 1919 from Area de Conservación Guanacaste (ACG) in northwestern Costa Rica. Both species were reared from wild-caughtcaterpillars of Eois spp. (Lepidoptera: Geometridae). We provide a concise description of each species using morphology, life history, molecular data, and photographic documentation. New information Erythromelana jimmychevezi Fleming & Wood sp. nov. Erythromelana glenriverai Fleming & Wood sp. nov. PMID:27226745

A Concise Review of Amyloidosis in Animals

PubMed Central

Woldemeskel, Moges

2012-01-01

Amyloidosis refers to a group of protein misfolding diseases characterized by deposition of a particular amyloid protein in various organs and tissues of animals and humans. Various types and clinical forms of amyloidosis, in which the pathology and pathogenesis is diverse depending upon the underlying causes and species affected, are reported in domestic and wild animals. The clinical findings are also quite variable consequent to the variation of the tissues and organs involved and the extent of functional disruption of the affected organs in various animal species. The affected organs may be enlarged and exhibit variable pallor grossly, or the amyloid deposit may be discernible only after microscopic examination of the affected tissues. Amyloid appears as a pale eosinophilic homogenous extracellular deposit in tissues. However, microscopic examination and Congo red staining with green birefringence under polarized light are needed to confirm amyloid and differentiate it from other apparently similar extracellular deposits such as collagen and fibrin. Identifying the type of amyloid deposit needs immunohistochemical staining, ultrastructural characterization of the amyloid fibril, and if feasible also genetic studies of the involved species for clinical and prognostic purposes. This paper provides a concise review of the occurrence of amyloidosis in domestic and wild animals. PMID:22577608

Orthodontic extrusion for pre-implant site enhancement: Principles and clinical guidelines.

PubMed

Alsahhaf, Abdulaziz; Att, Wael

2016-07-01

The aim of this paper is to provide a concise overview about the principles of pre-implant orthodontic extrusion, describe methods and techniques available and provide the clinicians with guidelines about its application. A number of reports describe orthodontic extrusion as a reliable method for pre-implant site enhancement. However, no standard protocols have been provided about the application of this technique. The literature database was searched for studies involving implant site enhancement by means of orthodontic extrusion. Information about the principles, indications and contraindications of this method, type of anchorage, force and time were obtained from the literature. Despite that the scarce data is largely limited to case reports and case series, implant site enhancement by means of orthodontic extrusion seems to be a promising option to improve soft and hard tissue conditions prior to implant placement. Orthodontic extrusion is being implemented as a treatment alternative to enhance hard and soft tissue prior to implant placement. While the current literature does not provide clear guidelines, the decision making for a specific approach seems to be based on the clinician's preferences. Clinical studies are needed to verify the validity of this treatment option. Copyright © 2016 Japan Prosthodontic Society. Published by Elsevier Ltd. All rights reserved.

Concise synthesis and PTP1B inhibitory activity of (R)- and (S)-dihydroresorcylide.

PubMed

Jiang, Cheng-Shi; Zhang, Li; Gong, Jing-Xu; Li, Jing-Ya; Yao, Li-Gong; Li, Jia; Guo, Yue-Wei

2017-12-01

The present study was designed to develop a concise synthetic route for macrolide, with the purpose of confirming the absolute configuration of natural dihydroresorcylide (1) and making it more easily accessible for biological evaluation. The absolute configuration of C-3 in natural 1 was revised to be R by comparison of the rotation sign of synthetic (R)- and (S)-1. The synthetic (R)-1 was found to be a novel highly specific PTP1B inhibitor with an IC 50 value of 17.06 μM.

A generalized memory test algorithm

NASA Technical Reports Server (NTRS)

Milner, E. J.

1982-01-01

A general algorithm for testing digital computer memory is presented. The test checks that (1) every bit can be cleared and set in each memory work, and (2) bits are not erroneously cleared and/or set elsewhere in memory at the same time. The algorithm can be applied to any size memory block and any size memory word. It is concise and efficient, requiring the very few cycles through memory. For example, a test of 16-bit-word-size memory requries only 384 cycles through memory. Approximately 15 seconds were required to test a 32K block of such memory, using a microcomputer having a cycle time of 133 nanoseconds.

Dependability and performability analysis

NASA Technical Reports Server (NTRS)

Trivedi, Kishor S.; Ciardo, Gianfranco; Malhotra, Manish; Sahner, Robin A.

1993-01-01

Several practical issues regarding specifications and solution of dependability and performability models are discussed. Model types with and without rewards are compared. Continuous-time Markov chains (CTMC's) are compared with (continuous-time) Markov reward models (MRM's) and generalized stochastic Petri nets (GSPN's) are compared with stochastic reward nets (SRN's). It is shown that reward-based models could lead to more concise model specifications and solution of a variety of new measures. With respect to the solution of dependability and performability models, three practical issues were identified: largeness, stiffness, and non-exponentiality, and a variety of approaches are discussed to deal with them, including some of the latest research efforts.

Diderot: a Domain-Specific Language for Portable Parallel Scientific Visualization and Image Analysis.

PubMed

Kindlmann, Gordon; Chiw, Charisee; Seltzer, Nicholas; Samuels, Lamont; Reppy, John

2016-01-01

Many algorithms for scientific visualization and image analysis are rooted in the world of continuous scalar, vector, and tensor fields, but are programmed in low-level languages and libraries that obscure their mathematical foundations. Diderot is a parallel domain-specific language that is designed to bridge this semantic gap by providing the programmer with a high-level, mathematical programming notation that allows direct expression of mathematical concepts in code. Furthermore, Diderot provides parallel performance that takes advantage of modern multicore processors and GPUs. The high-level notation allows a concise and natural expression of the algorithms and the parallelism allows efficient execution on real-world datasets.

Magnetic resonance imaging of the pediatric neck: an overview.

PubMed

Shekdar, Karuna V; Mirsky, David M; Kazahaya, Ken; Bilaniuk, Larissa T

2012-08-01

Evaluation of neck lesions in the pediatric population can be a diagnostic challenge, for which magnetic resonance (MR) imaging is extremely valuable. This article provides an overview of the value and utility of MR imaging in the evaluation of pediatric neck lesions, addressing what the referring clinician requires from the radiologist. Concise descriptions and illustrations of MR imaging findings of commonly encountered pathologic entities in the pediatric neck, including abnormalities of the branchial apparatus, thyroglossal duct anomalies, and neoplastic processes, are given. An approach to establishing a differential diagnosis is provided, and critical points of information are summarized. Copyright © 2012 Elsevier Inc. All rights reserved.

Flight Dynamics Analysis Branch

NASA Technical Reports Server (NTRS)

Stengle, Tom; Flores-Amaya, Felipe

2000-01-01

This report summarizes the major activities and accomplishments carried out by the Flight Dynamics Analysis Branch (FDAB), Code 572, in support of flight projects and technology development initiatives in fiscal year 2000. The report is intended to serve as a summary of the type of support carried out by the FDAB, as well as a concise reference of key accomplishments and mission experience derived from the various mission support roles. The primary focus of the FDAB is to provide expertise in the disciplines of flight dynamics, spacecraft trajectory, attitude analysis, and attitude determination and control. The FDAB currently provides support for missions and technology development projects involving NASA, government, university, and private industry.

A new species of Cordyligaster Macquart, reared from caterpillars in Area de Conservacion Guanacaste, northwestern Costa Rica

PubMed Central

Wood, D Monty; Smith, M Alex; Janzen, Daniel; Hallwachs, Winnie

2014-01-01

Abstract We describe a new species of Cordyligaster Macquart (Diptera: Tachinidae) from Area de Conservacion Guanacaste (ACG) in northwestern Costa Rica. Cordyligaster capellii sp. n., is described and photographed. All specimens of C. capellii were reared from Syngamia florella (Stoll, 1781) (Lepidoptera, Crambidae, Spilomelinae), a leaf-rolling caterpillar collected in ACG rain forest. By coupling morphology, photographic documentation, life history and molecular data, we provide a clear and concise description of this new species. In addition the authors provide new distribution and host records for C. fuscipennis (Macquart) reared in ACG. PMID:25535485

User-Centered Design and Printed Educational Materials: A Focus Group Study of Primary Care Physician Preferences.

PubMed

Grudniewicz, Agnes; Bhattacharyya, Onil; McKibbon, K Ann; Straus, Sharon E

2016-01-01

It is challenging for primary care physicians (PCPs) to review and apply the growing amount of clinical evidence available. Printed educational materials (PEMs), which synthesize evidence, are often ineffective at improving knowledge, possibly due to poor design and limited uptake. In this study, we collected PCP preferences for the design and content of physician-oriented PEMs and determined key attributes that may increase their usability and uptake. We held 90-minute focus groups with PCPs in Toronto, ON, Canada. Focus groups included discussion about whether and how participants use PEMs, feedback on three examples of PEMs, and a discussion on general format and design preferences in PEMs. We analyzed focus group transcripts using a thematic analysis and summarized results in a list of user preferences. Four focus groups were held with 13 PCPs. We found that participants only read PEMs relevant to their patients and prefer short, concise documents, with links to sources that can provide more detailed information. Simplicity of materials was important, with many participants preferring PEMs without lengthy backgrounds or scientific explanations. Most participants wanted to see key messages highlighted to easily assess the relevance of the materials to their practice. Some participants shared physician-oriented PEMs with patients. This study shows that PCPs may prefer shorter, simpler, and more concise documents that have less scientific detail but provide references to further information sources. It is important to understand end user preferences for the design and content of these materials to enhance their uptake.

The Development and Validation of a Concise Instrument for Formative Assessment of Team Leader Performance During Simulated Pediatric Resuscitations.

PubMed

Nadkarni, Lindsay D; Roskind, Cindy G; Auerbach, Marc A; Calhoun, Aaron W; Adler, Mark D; Kessler, David O

2018-04-01

The aim of this study was to assess the validity of a formative feedback instrument for leaders of simulated resuscitations. This is a prospective validation study with a fully crossed (person × scenario × rater) study design. The Concise Assessment of Leader Management (CALM) instrument was designed by pediatric emergency medicine and graduate medical education experts to be used off the shelf to evaluate and provide formative feedback to resuscitation leaders. Four experts reviewed 16 videos of in situ simulated pediatric resuscitations and scored resuscitation leader performance using the CALM instrument. The videos consisted of 4 pediatric emergency department resuscitation teams each performing in 4 pediatric resuscitation scenarios (cardiac arrest, respiratory arrest, seizure, and sepsis). We report on content and internal structure (reliability) validity of the CALM instrument. Content validity was supported by the instrument development process that involved professional experience, expert consensus, focused literature review, and pilot testing. Internal structure validity (reliability) was supported by the generalizability analysis. The main component that contributed to score variability was the person (33%), meaning that individual leaders performed differently. The rater component had almost zero (0%) contribution to variance, which implies that raters were in agreement and argues for high interrater reliability. These results provide initial evidence to support the validity of the CALM instrument as a reliable assessment instrument that can facilitate formative feedback to leaders of pediatric simulated resuscitations.

Advances in Theory of Solid-State Nuclear Magnetic Resonance.

PubMed

Mananga, Eugene S; Moghaddasi, Jalil; Sana, Ajaz; Akinmoladun, Andrew; Sadoqi, Mostafa

Recent advances in theory of solid state nuclear magnetic resonance (NMR) such as Floquet-Magnus expansion and Fer expansion, address alternative methods for solving a time-dependent linear differential equation which is a central problem in quantum physics in general and solid-state NMR in particular. The power and the salient features of these theoretical approaches that are helpful to describe the time evolution of the spin system at all times are presented. This review article presents a broad view of manipulations of spin systems in solid-state NMR, based on milestones theories including the average Hamiltonian theory and the Floquet theory, and the approaches currently developing such as the Floquet-Magnus expansion and the Fer expansion. All these approaches provide procedures to control and describe the spin dynamics in solid-state NMR. Applications of these theoretical methods to stroboscopic and synchronized manipulations, non-synchronized experiments, multiple incommensurated frequencies, magic-angle spinning samples, are illustrated. We also reviewed the propagators of these theories and discussed their convergences. Note that the FME is an extension of the popular Magnus Expansion and Average Hamiltonian Theory. It aims is to bridge the AHT to the Floquet Theorem but in a more concise and efficient formalism. Calculations can then be performed in a finite-dimensional Hilbert space instead of an infinite dimensional space within the so-called Floquet theory. We expected that the FME will provide means for more accurate and efficient spin dynamics simulation and for devising new RF pulse sequence.

New and emerging therapies for acute and chronic graft versus host disease

PubMed Central

Hill, LaQuisa; Alousi, Amin; Kebriaei, Partow; Mehta, Rohtesh; Rezvani, Katayoun; Shpall, Elizabeth

2017-01-01

Graft versus host disease (GVHD) remains a major cause of morbidity and mortality following allogeneic hematopoietic stem-cell transplantation (HSCT). Despite the use of prophylactic GVHD regimens, a significant proportion of transplant recipients will develop acute or chronic GVHD following HSCT. Corticosteroids are standard first-line therapy, but are only effective in roughly half of all cases with ~50% of patients going on to develop steroid-refractory disease, which increases the risk of nonrelapse mortality. While progress has been made with improvements in survival outcomes over time, corticosteroids are associated with significant toxicities, and many currently available salvage therapies are associated with increased immunosuppression, infectious complications, and potential loss of the graft versus leukemia (GVL) effect. Thus, there is an unmet need for development of newer treatment strategies for both acute and chronic GVHD to improve long-term post-transplant outcomes and quality of life for HSCT recipients. Here, we provide a concise review of major emerging therapies currently being studied in the treatment of acute and chronic GVHD. PMID:29317998

Multi-Infarct Dementia: A Historical Perspective.

PubMed

McKay, Erin; Counts, Scott E

2017-01-01

Multi-infarct dementia (MID), a prominent subtype of vascular dementia (VaD), has only achieved recognition in the last 4 decades. Since its original description, the characterization, etiological understanding, and therapeutic direction of MID and other VaD subtypes has progressed at an astounding rate. This paper divides the landmark discoveries and emergence of new research strategies for MID into decade-defining patterns so that a condensed picture of the total history of MID and its eventual inclusion as a VaD subtype emerges. This paper follows the first descriptive decade, a shift to a preventative focus, a renewed interest coinciding with timely advances in research technology, and a hopeful return to treatment possibilities for VaD. Concisely tracing the historical lineage of the modern understanding of MID, both as a singular entity and as part of the VaD con-stellation of disorders, provides a novel perspective on the foundation upon which future advances in combating vascular contributions to dementia will be based.

Contribution of low-temperature single-molecule techniques to structural issues of pigment–protein complexes from photosynthetic purple bacteria

PubMed Central

Löhner, Alexander; Cogdell, Richard

2018-01-01

As the electronic energies of the chromophores in a pigment–protein complex are imposed by the geometrical structure of the protein, this allows the spectral information obtained to be compared with predictions derived from structural models. Thereby, the single-molecule approach is particularly suited for the elucidation of specific, distinctive spectral features that are key for a particular model structure, and that would not be observable in ensemble-averaged spectra due to the heterogeneity of the biological objects. In this concise review, we illustrate with the example of the light-harvesting complexes from photosynthetic purple bacteria how results from low-temperature single-molecule spectroscopy can be used to discriminate between different structural models. Thereby the low-temperature approach provides two advantages: (i) owing to the negligible photobleaching, very long observation times become possible, and more importantly, (ii) at cryogenic temperatures, vibrational degrees of freedom are frozen out, leading to sharper spectral features and in turn to better resolved spectra. PMID:29321265

Use of Bayesian Methods to Analyze and Visualize Content Uniformity Capability Versus United States Pharmacopeia and ASTM Standards.

PubMed

Hofer, Jeffrey D; Rauk, Adam P

2017-02-01

The purpose of this work was to develop a straightforward and robust approach to analyze and summarize the ability of content uniformity data to meet different criteria. A robust Bayesian statistical analysis methodology is presented which provides a concise and easily interpretable visual summary of the content uniformity analysis results. The visualization displays individual batch analysis results and shows whether there is high confidence that different content uniformity criteria could be met a high percentage of the time in the future. The 3 tests assessed are as follows: (a) United States Pharmacopeia Uniformity of Dosage Units <905>, (b) a specific ASTM E2810 Sampling Plan 1 criterion to potentially be used for routine release testing, and (c) another specific ASTM E2810 Sampling Plan 2 criterion to potentially be used for process validation. The approach shown here could readily be used to create similar result summaries for other potential criteria. Copyright © 2017 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.

Winter fuels report, week ending November 12, 1993

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1993-11-18

The Winter Fuels Report is intended to provide concise, timely information to the industry, the press, policymakers, consumers, analysts, and State and local governments on the following topics: Distillate fuel oil net production, imports and stocks on a US level and for all Petroleum Administration for Defense Districts (PADD) and product supplied on a US level; propane net production, imports and stocks on a US level and for PADD`s I, II, and III; natural gas supply and disposition and underground storage for the US and consumption for all PADD`S; as well as selected National average prices; residential and wholesale pricingmore » data for heating oil and propane for those States participating in the joint Energy Information Administration (EIA)/State Heating Oil and Propane Program; crude oil and petroleum price comparisons for the US and selected cities; and a 6--10 Day, 30-Day, and 90-Day outlook for temperature and precipitation and US total heating degree-days by city.« less

Paintball-related traumatic liver injury

PubMed Central

Luck, Joshua; Bell, Daniel; Bashir, Gareth

2016-01-01

Paintball is a popular recreational sport played at both amateur and professional level. Ocular injuries are well recognised, although there is a growing body of literature documenting superficial vascular as well as deep solid organ injuries. An 18-year-old man presented with signs and symptoms consistent with acute appendicitis. Intraoperatively, a grade III liver injury was identified and packed before a relook at 48 h. No further active bleeding was identified; however, follow-up ultrasound at 3 weeks demonstrated non-resolution of a large subcapsular haematoma. The patient was readmitted for a short period of observation and discharged with repeat ultrasound scheduled for 3 months. This represents the first report of paintball-related blunt traumatic injury to the liver. Solid organ injuries of this nature have only been reported three times previously—all in the urological setting. This case also highlights issues surrounding the use of routine follow-up imaging in blunt liver trauma and provides a concise discussion of the relevant literature. PMID:27122206

Imaging, Health Record, and Artificial Intelligence: Hype or Hope?

PubMed

Mazzanti, Marco; Shirka, Ervina; Gjergo, Hortensia; Hasimi, Endri

2018-05-10

The review is focused on "digital health", which means advanced analytics based on multi-modal data. The "Health Care Internet of Things", which uses sensors, apps, and remote monitoring could provide continuous clinical information in the cloud that enables clinicians to access the information they need to care for patients everywhere. Greater standardization of acquisition protocols will be needed to maximize the potential gains from automation and machine learning. Recent artificial intelligence applications on cardiac imaging will not be diagnosing patients and replacing doctors but will be augmenting their ability to find key relevant data they need to care for a patient and present it in a concise, easily digestible format. Risk stratification will transition from oversimplified population-based risk scores to machine learning-based metrics incorporating a large number of patient-specific clinical and imaging variables in real-time beyond the limits of human cognition. This will deliver highly accurate and individual personalized risk assessments and facilitate tailored management plans.

Electron emission controller with pulsed heating of filament

NASA Astrophysics Data System (ADS)

Durakiewicz, Tomasz

1996-11-01

A novel circuit has been invented for the versatile and safe stabilization of the electron emission current (Ie) produced by a hot filament in mass spectrometers or in ionization gauges. The voltage signal, which is directly proportional to Ie, is provided to the inverting input of a comparator, whereas the noninverting input is connected to the reference voltage. In addition to the commonly used negative feedback loop, a positive feedback loop was introduced by siting a resistor between the noninverting input and the output of the comparator, which results in a pulsation of the filament voltage. The pulses are rectangular, so that the power dissipated by the transistor in the filament power supply circuit is radically reduced. To refine the switching action of the transistor, the output of the comparator is connected through a capacitor to the transistor gate. A concise discussion of the phase shift between Ie, the filament temperature Tf, and the filament voltage Vf, including time constants for different modes of power dissipation, is included.

Theories of Matter, Space and Time; Classical theories

NASA Astrophysics Data System (ADS)

Evans, N.; King, S. F.

2017-12-01

This book and its sequel ('Theories of Matter Space and Time: Quantum Theories') are taken from third and fourth year undergraduate Physics courses at Southampton University, UK. The aim of both books is to move beyond the initial courses in classical mechanics, special relativity, electromagnetism, and quantum theory to more sophisticated views of these subjects and their interdependence. The goal is to guide undergraduates through some of the trickier areas of theoretical physics with concise analysis while revealing the key elegance of each subject. The first chapter introduces the key areas of the principle of least action, an alternative treatment of Newtownian dynamics, that provides new understanding of conservation laws. In particular, it shows how the formalism evolved from Fermat's principle of least time in optics. The second introduces special relativity leading quickly to the need and form of four-vectors. It develops four-vectors for all kinematic variables and generalize Newton's second law to the relativistic environment; then returns to the principle of least action for a free relativistic particle. The third chapter presents a review of the integral and differential forms of Maxwell's equations before massaging them to four-vector form so that the Lorentz boost properties of electric and magnetic fields are transparent. Again, it then returns to the action principle to formulate minimal substitution for an electrically charged particle.

Modified Hawking radiation in a BTZ black hole using Damour Ruffini method

NASA Astrophysics Data System (ADS)

He, Xiaokai; Liu, Wenbiao

2007-09-01

Considering energy conservation, angular momentum conservation, and the particles' back reaction to space-time, the scalar particles' Hawking radiation from a BTZ black hole was investigated using Damour-Ruffini method. The exact expression of the emission rate near the horizon is obtained and the result indicates that Hawking radiation spectrum is not purely thermal. The result obtained is consistent with the previous literatures. It is in agreement with an underlying unitary theory and offers a possible mechanism to explain the information loss paradox. Whereas, the method is more concise and understandable.

Basic Strategies of Dynamic Supportive Therapy

PubMed Central

Misch, Donald A.

2000-01-01

Supportive therapy is the psychotherapeutic approach employed with the majority of mentally ill individuals. Nevertheless, most mental health professional training programs dedicate little time and effort to the teaching and learning of supportive therapy, and many mental health professionals are unable to clearly and concisely articulate the nature or process of supportive work. Although supportive therapy incorporates many specific techniques from a wide variety of psychotherapy schools, it can be conceptualized as consisting of a more limited number of underlying strategies. The fundamental strategies that underpin effective supportive therapy with mentally ill individuals are described. PMID:11069130

Selecting automation for the clinical chemistry laboratory.

PubMed

Melanson, Stacy E F; Lindeman, Neal I; Jarolim, Petr

2007-07-01

Laboratory automation proposes to improve the quality and efficiency of laboratory operations, and may provide a solution to the quality demands and staff shortages faced by today's clinical laboratories. Several vendors offer automation systems in the United States, with both subtle and obvious differences. Arriving at a decision to automate, and the ensuing evaluation of available products, can be time-consuming and challenging. Although considerable discussion concerning the decision to automate has been published, relatively little attention has been paid to the process of evaluating and selecting automation systems. To outline a process for evaluating and selecting automation systems as a reference for laboratories contemplating laboratory automation. Our Clinical Chemistry Laboratory staff recently evaluated all major laboratory automation systems in the United States, with their respective chemistry and immunochemistry analyzers. Our experience is described and organized according to the selection process, the important considerations in clinical chemistry automation, decisions and implementation, and we give conclusions pertaining to this experience. Including the formation of a committee, workflow analysis, submitting a request for proposal, site visits, and making a final decision, the process of selecting chemistry automation took approximately 14 months. We outline important considerations in automation design, preanalytical processing, analyzer selection, postanalytical storage, and data management. Selecting clinical chemistry laboratory automation is a complex, time-consuming process. Laboratories considering laboratory automation may benefit from the concise overview and narrative and tabular suggestions provided.

Conditionally Teleported States Using Optical Squeezers and Photon Counting

NASA Astrophysics Data System (ADS)

Fan, Hong-Yi; Fan, Yue; Cheng, Hai-Ling

2002-04-01

By virtue of the neat expression of the two-mode squeezing operator in the Einstein, Podolsky and Rosen entangled state representation, we provide a new approach for discussing the teleportation scheme using optical squeezers and photon counting devices. We derive the explicit form of the teleported states, so that the conditional property of teleportation and teleportation fidelity of this protocol can be seen more clearly. The derivation is concise. The project supported by the President Foundation of the Chinese Academy of Sciences and National Natural Science Foundation of China

A concise synthesis of benzimidazoles via the microwave-assisted one-pot batch reaction of amino acids up to a 10-g scale.

PubMed

Peng, Pai; Xiong, Jin-Feng; Mo, Guang-Zhen; Zheng, Jia-Li; Chen, Ren-Hong; Chen, Xiao-Yun; Wang, Zhao-Yang

2014-10-01

An efficient method for the synthesis of aminomethyl benzimidazoles is developed by using a one-pot batch reaction between amino acids and o-phenylenediamines. This reaction proceeds smoothly in an unmodified household microwave oven, even though scale-up is to 10 g. A desirable method for the quick synthesis of benzimidazoles, which are used as a kind of important intermediates in drug synthesis, is provided by the scale-up utilization of amino acid resource.

Nuclear medicine imaging and therapy of neuroendocrine tumours

PubMed Central

Gotthardt, Martin; Dijkgraaf, Ingrid; Boerman, Otto C; Oyen, Wim J G

2006-01-01

Radiolabelled peptides are used for specific targeting of receptors (over-)expressed by tumour cells. Dependent on the kind of labelling and the radionuclide used, these compounds may be utilised for imaging or for therapy. A concise overview is provided on basic principles of designing and developing radiopeptides for these applications. Furthermore, clinical application of these compounds for imaging and therapy is described. Advantages of the method compared to other techniques (such as the use of radiolabelled antibodies or antibody fragments) are discussed as well as pitfalls and limitations. PMID:17114073

Sheep (Ovis aries) as a Model for Cardiovascular Surgery and Management before, during, and after Cardiopulmonary Bypass

PubMed Central

DiVincenti, Louis; Westcott, Robin; Lee, Candice

2014-01-01

Because of its similarity to humans in important respects, sheep (Ovis aries) are a common animal model for translational research in cardiovascular surgery. However, some unique aspects of sheep anatomy and physiology present challenges to its use in these complicated experiments. In this review, we discuss relevant anatomy and physiology of sheep and discuss management before, during, and after procedures requiring cardiopulmonary bypass to provide a concise source of information for veterinarians, technicians, and researchers developing and implementing protocols with this model. PMID:25255065

Use of Ni63 Overvoltage Gap Switches in the Flight Termination Systems on Boosters Launched from U.S. Army Kwajalein Atoll (USAKA)

DTIC Science & Technology

1990-05-01

J3 w c’f oz us~ w - 0n fn 00:1 0 Ic 0 L o 0j 0 0I LL 0 Iof the less than adequate reliability of the earlier Exploding Foil Initiator ( EFI ) design...Action and Alternatives EFI Exploding Foil Initiator Environmental Assessment (EA) A concise public document in which a Federal agency provides...Interceptor (GBI) firing unit (the Explosive Foil Initiator ) was built and tested, it operated unreliably. Many hardware development problems were

Quantum Chemistry; A concise introduction for students of physics, chemistry, biochemistry and materials science

NASA Astrophysics Data System (ADS)

Thakkar, Ajit J.

2017-09-01

This book provides non-specialists with a basic understanding of the underlying concepts of quantum chemistry. It is both a text for second- or third-year undergraduates and a reference for researchers who need a quick introduction or refresher. All chemists and many biochemists, materials scientists, engineers, and physicists routinely use spectroscopic measurements and electronic structure computations in their work. The emphasis of Quantum Chemistry on explaining ideas rather than enumerating facts or presenting procedural details makes this an excellent foundation text/reference.

Pathological narcissism and the obstruction of love.

PubMed

Kealy, David; Ogrodniczuk, John S

2014-03-01

Pathological narcissism is a form of maladaptive self-regulation that impedes the capacity to love. Although narcissism is often construed as excessive self-love, individuals with pathological narcissism are impaired in being able to love themselves as well as others. With the subject of impaired love in mind, we review selected conceptualizations from an enormous and diverse psychodynamic literature on narcissism. Major theoretical approaches illustrate a number of psychodynamics associated with narcissistic self-regulatory problems. This paper provides a concise overview of major conceptual themes regarding pathological narcissism and impaired capacity to love.

Perovskite Solar Cells—Towards Commercialization

DOE PAGES

Ono, Luis K.; Park, Nam-Gyu; Zhu, Kai; ...

2017-07-13

The Symposium ES1, Perovskite Solar Cells - Towards Commercialization, held at the 2017 Materials Research Society (MRS) Spring Meeting in Phoenix, Arizona (April 17-21, 2017) received ~200 abstracts. The 23 invited talks and 72 contributed oral presentations as well as 3 poster presentation sessions were organized into 13 principal themes according to the contents of the received abstracts. This Energy Focus article provides a concise summary of the opinions from the scientists and engineers who participated in this symposium regarding the recent progresses, challenges, and future directions for perovskite solar cells as well as other optoelectronic devices.

Applications of aerospace technology in industry: A technology transfer profile. Visual display systems

NASA Technical Reports Server (NTRS)

1972-01-01

The growth of common as well as emerging visual display technologies are surveyed. The major inference is that contemporary society is rapidly growing evermore reliant on visual display for a variety of purposes. Because of its unique mission requirements, the National Aeronautics and Space Administration has contributed in an important and specific way to the growth of visual display technology. These contributions are characterized by the use of computer-driven visual displays to provide an enormous amount of information concisely, rapidly and accurately.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ono, Luis K.; Park, Nam-Gyu; Zhu, Kai

The Symposium ES1, Perovskite Solar Cells - Towards Commercialization, held at the 2017 Materials Research Society (MRS) Spring Meeting in Phoenix, Arizona (April 17-21, 2017) received ~200 abstracts. The 23 invited talks and 72 contributed oral presentations as well as 3 poster presentation sessions were organized into 13 principal themes according to the contents of the received abstracts. This Energy Focus article provides a concise summary of the opinions from the scientists and engineers who participated in this symposium regarding the recent progresses, challenges, and future directions for perovskite solar cells as well as other optoelectronic devices.

Integrated Science Assessment (ISA) for Sulfur Oxides ...

EPA Pesticide Factsheets

EPA has announced that the Second External Review Draft of the Integrated Science Assessment (ISA) for Sulfur Oxides – Health Criteria has been made available for independent peer review and public review. This draft ISA document represents a concise synthesis and evaluation of the most policy-relevant science and will ultimately provide the scientific bases for EPA’s decision regarding whether the current standard for SO2 sufficiently protects public health. Sulfur oxides is one of six principal (or “criteria”) pollutants for which EPA has established national ambient air quality standards (NAAQS).

Irritable bowel syndrome: a concise review of current treatment concepts.

PubMed

Wall, Geoffrey C; Bryant, Ginelle A; Bottenberg, Michelle M; Maki, Erik D; Miesner, Andrew R

2014-07-21

Irritable bowel syndrome (IBS) is one of the most common gastrointestinal disorders causing patients to seek medical treatment. It is relatively resource intensive and the source of significant morbidity. Recent insights into the pathophysiology and treatment of IBS has given clinicians more options than ever to contend with this disorder. The purpose of our paper is to review older, "classic" treatments for IBS as well as newer agents and "alternative" therapies. We discuss the evidence base of these drugs and provide context to help develop appropriate treatment plans for IBS patients.

Integrated Science Assessment (ISA) for Sulfur Oxides ...

EPA Pesticide Factsheets

EPA has announced that the First External Review Draft of the Integrated Science Assessment (ISA) for Sulfur Oxides – Health Criteria has been made available for independent peer review and public review. This draft ISA document represents a concise synthesis and evaluation of the most policy-relevant science and will ultimately provide the scientific bases for EPA’s decision regarding whether the current standard for SO2 sufficiently protects public health. Sulfur oxides is one of six principal (or “criteria”) pollutants for which EPA has established national ambient air quality standards (NAAQS).

Minimally invasive aortic valve replacement – pros and cons of keyhole aortic surgery

PubMed Central

Szałański, Przemysław; Zembala, Michał; Filipiak, Krzysztof; Karolak, Wojciech; Wojarski, Jacek; Garbacz, Marcin; Kaczmarczyk, Aleksandra; Kwiecień, Anna; Zembala, Marian

2015-01-01

Over the last twenty years, minimally invasive aortic valve replacement (MIAVR) has evolved into a safe, well-tolerated and efficient surgical treatment option for aortic valve disease. It has been shown to reduce postoperative morbidity, providing faster recovery and rehabilitation, shorter hospital stay and better cosmetic results compared with conventional surgery. A variety of minimally invasive accesses have been developed and utilized to date. This concise review demonstrates and discusses surgical techniques used in contemporary approaches to MIAVR and presents the most important results of MIAVR procedures. PMID:26336491

Courses of action for effects based operations using evolutionary algorithms

NASA Astrophysics Data System (ADS)

Haider, Sajjad; Levis, Alexander H.

2006-05-01

This paper presents an Evolutionary Algorithms (EAs) based approach to identify effective courses of action (COAs) in Effects Based Operations. The approach uses Timed Influence Nets (TINs) as the underlying mathematical model to capture a dynamic uncertain situation. TINs provide a concise graph-theoretic probabilistic approach to specify the cause and effect relationships that exist among the variables of interest (actions, desired effects, and other uncertain events) in a problem domain. The purpose of building these TIN models is to identify and analyze several alternative courses of action. The current practice is to use trial and error based techniques which are not only labor intensive but also produce sub-optimal results and are not capable of modeling constraints among actionable events. The EA based approach presented in this paper is aimed to overcome these limitations. The approach generates multiple COAs that are close enough in terms of achieving the desired effect. The purpose of generating multiple COAs is to give several alternatives to a decision maker. Moreover, the alternate COAs could be generalized based on the relationships that exist among the actions and their execution timings. The approach also allows a system analyst to capture certain types of constraints among actionable events.

The Sequenced Angiosperm Genomes and Genome Databases.

PubMed

Chen, Fei; Dong, Wei; Zhang, Jiawei; Guo, Xinyue; Chen, Junhao; Wang, Zhengjia; Lin, Zhenguo; Tang, Haibao; Zhang, Liangsheng

2018-01-01

Angiosperms, the flowering plants, provide the essential resources for human life, such as food, energy, oxygen, and materials. They also promoted the evolution of human, animals, and the planet earth. Despite the numerous advances in genome reports or sequencing technologies, no review covers all the released angiosperm genomes and the genome databases for data sharing. Based on the rapid advances and innovations in the database reconstruction in the last few years, here we provide a comprehensive review for three major types of angiosperm genome databases, including databases for a single species, for a specific angiosperm clade, and for multiple angiosperm species. The scope, tools, and data of each type of databases and their features are concisely discussed. The genome databases for a single species or a clade of species are especially popular for specific group of researchers, while a timely-updated comprehensive database is more powerful for address of major scientific mysteries at the genome scale. Considering the low coverage of flowering plants in any available database, we propose construction of a comprehensive database to facilitate large-scale comparative studies of angiosperm genomes and to promote the collaborative studies of important questions in plant biology.

Novel Pentablock Copolymers as Thermosensitive Self-Assembling Micelles for Ocular Drug Delivery

PubMed Central

Alami-Milani, Mitra; Zakeri-Milani, Parvin; Valizadeh, Hadi; Salehi, Roya; Salatin, Sara; Naderinia, Ali; Jelvehgari, Mitra

2017-01-01

Many studies have focused on how drugs are formulated in the sol state at room temperature leading to the formation of in situ gel at eye temperature to provide a controlled drug release. Stimuli-responsive block copolymer hydrogels possess several advantages including uncomplicated drug formulation and ease of application, no organic solvent, protective environment for drugs, site-specificity, prolonged and localized drug delivery, lower systemic toxicity, and capability to deliver both hydrophobic and hydrophilic drugs. Self-assembling block copolymers (such as diblock, triblock, and pentablock copolymers) with large solubility variation between hydrophilic and hydrophobic segments are capable of making temperature-dependent micellar assembles, and with further increase in the temperature, of jellifying due to micellar aggregation. In general, molecular weight, hydrophobicity, and block arrangement have a significant effect on polymer crystallinity, micelle size, and in vitro drug release profile. The limitations of creature triblock copolymers as initial burst release can be largely avoided using micelles made of pentablock copolymers. Moreover, formulations based on pentablock copolymers can sustain drug release for a longer time. The present study aims to provide a concise overview of the initial and recent progresses in the design of hydrogel-based ocular drug delivery systems. PMID:28507933

The Sequenced Angiosperm Genomes and Genome Databases

PubMed Central

Chen, Fei; Dong, Wei; Zhang, Jiawei; Guo, Xinyue; Chen, Junhao; Wang, Zhengjia; Lin, Zhenguo; Tang, Haibao; Zhang, Liangsheng

2018-01-01

Angiosperms, the flowering plants, provide the essential resources for human life, such as food, energy, oxygen, and materials. They also promoted the evolution of human, animals, and the planet earth. Despite the numerous advances in genome reports or sequencing technologies, no review covers all the released angiosperm genomes and the genome databases for data sharing. Based on the rapid advances and innovations in the database reconstruction in the last few years, here we provide a comprehensive review for three major types of angiosperm genome databases, including databases for a single species, for a specific angiosperm clade, and for multiple angiosperm species. The scope, tools, and data of each type of databases and their features are concisely discussed. The genome databases for a single species or a clade of species are especially popular for specific group of researchers, while a timely-updated comprehensive database is more powerful for address of major scientific mysteries at the genome scale. Considering the low coverage of flowering plants in any available database, we propose construction of a comprehensive database to facilitate large-scale comparative studies of angiosperm genomes and to promote the collaborative studies of important questions in plant biology. PMID:29706973

Bridging the gap between system and cell: The role of ultra-high field MRI in human neuroscience.

PubMed

Turner, Robert; De Haan, Daniel

2017-01-01

The volume of published research at the levels of systems and cellular neuroscience continues to increase at an accelerating rate. At the same time, progress in psychiatric medicine has stagnated and scientific confidence in cognitive psychology research is under threat due to careless analysis methods and underpowered experiments. With the advent of ultra-high field MRI, with submillimeter image voxels, imaging neuroscience holds the potential to bridge the cellular and systems levels. Use of these accurate and precisely localized quantitative measures of brain activity may go far in providing more secure foundations for psychology, and hence for more appropriate treatment and management of psychiatric illness. However, fundamental issues regarding the construction of testable mechanistic models using imaging data require careful consideration. This chapter summarizes the characteristics of acceptable models of brain function and provides concise descriptions of the relevant types of neuroimaging data that have recently become available. Approaches to data-driven experiments and analyses are described that may lead to more realistic conceptions of the competences of neural assemblages, as they vary across the brain's complex neuroanatomy. © 2017 Elsevier B.V. All rights reserved.

BiNA: A Visual Analytics Tool for Biological Network Data

PubMed Central

Gerasch, Andreas; Faber, Daniel; Küntzer, Jan; Niermann, Peter; Kohlbacher, Oliver; Lenhof, Hans-Peter; Kaufmann, Michael

2014-01-01

Interactive visual analysis of biological high-throughput data in the context of the underlying networks is an essential task in modern biomedicine with applications ranging from metabolic engineering to personalized medicine. The complexity and heterogeneity of data sets require flexible software architectures for data analysis. Concise and easily readable graphical representation of data and interactive navigation of large data sets are essential in this context. We present BiNA - the Biological Network Analyzer - a flexible open-source software for analyzing and visualizing biological networks. Highly configurable visualization styles for regulatory and metabolic network data offer sophisticated drawings and intuitive navigation and exploration techniques using hierarchical graph concepts. The generic projection and analysis framework provides powerful functionalities for visual analyses of high-throughput omics data in the context of networks, in particular for the differential analysis and the analysis of time series data. A direct interface to an underlying data warehouse provides fast access to a wide range of semantically integrated biological network databases. A plugin system allows simple customization and integration of new analysis algorithms or visual representations. BiNA is available under the 3-clause BSD license at http://bina.unipax.info/. PMID:24551056

Zernike expansion of derivatives and Laplacians of the Zernike circle polynomials.

PubMed

Janssen, A J E M

2014-07-01

The partial derivatives and Laplacians of the Zernike circle polynomials occur in various places in the literature on computational optics. In a number of cases, the expansion of these derivatives and Laplacians in the circle polynomials are required. For the first-order partial derivatives, analytic results are scattered in the literature. Results start as early as 1942 in Nijboer's thesis and continue until present day, with some emphasis on recursive computation schemes. A brief historic account of these results is given in the present paper. By choosing the unnormalized version of the circle polynomials, with exponential rather than trigonometric azimuthal dependence, and by a proper combination of the two partial derivatives, a concise form of the expressions emerges. This form is appropriate for the formulation and solution of a model wavefront sensing problem of reconstructing a wavefront on the level of its expansion coefficients from (measurements of the expansion coefficients of) the partial derivatives. It turns out that the least-squares estimation problem arising here decouples per azimuthal order m, and per m the generalized inverse solution assumes a concise analytic form so that singular value decompositions are avoided. The preferred version of the circle polynomials, with proper combination of the partial derivatives, also leads to a concise analytic result for the Zernike expansion of the Laplacian of the circle polynomials. From these expansions, the properties of the Laplacian as a mapping from the space of circle polynomials of maximal degree N, as required in the study of the Neumann problem associated with the transport-of-intensity equation, can be read off within a single glance. Furthermore, the inverse of the Laplacian on this space is shown to have a concise analytic form.

Tutorial: Magnetic resonance with nitrogen-vacancy centers in diamond—microwave engineering, materials science, and magnetometry

NASA Astrophysics Data System (ADS)

Abe, Eisuke; Sasaki, Kento

2018-04-01

This tutorial article provides a concise and pedagogical overview on negatively charged nitrogen-vacancy (NV) centers in diamond. The research on the NV centers has attracted enormous attention for its application to quantum sensing, encompassing the areas of not only physics and applied physics but also chemistry, biology, and life sciences. Nonetheless, its key technical aspects can be understood from the viewpoint of magnetic resonance. We focus on three facets of this ever-expanding research field, to which our viewpoint is especially relevant: microwave engineering, materials science, and magnetometry. In explaining these aspects, we provide a technical basis and up-to-date technologies for research on the NV centers.

Tectonic summaries of magnitude 7 and greater earthquakes from 2000 to 2015

USGS Publications Warehouse

Hayes, Gavin P.; Meyers, Emma K.; Dewey, James W.; Briggs, Richard W.; Earle, Paul S.; Benz, Harley M.; Smoczyk, Gregory M.; Flamme, Hanna E.; Barnhart, William D.; Gold, Ryan D.; Furlong, Kevin P.

2017-01-11

This paper describes the tectonic summaries for all magnitude 7 and larger earthquakes in the period 2000–2015, as produced by the U.S. Geological Survey National Earthquake Information Center during their routine response operations to global earthquakes. The goal of such summaries is to provide important event-specific information to the public rapidly and concisely, such that recent earthquakes can be understood within a global and regional seismotectonic framework. We compile these summaries here to provide a long-term archive for this information, and so that the variability in tectonic setting and earthquake history from region to region, and sometimes within a given region, can be more clearly understood.

The evolution of infectious agents in relation to sex in animals and humans: brief discussions of some individual organisms

PubMed Central

Reed, David L.; Currier, Russell W.; Walton, Shelley F.; Conrad, Melissa; Sullivan, Steven A.; Carlton, Jane M.; Read, Timothy D.; Severini, Alberto; Tyler, Shaun; Eberle, R.; Johnson, Welkin E.; Silvestri, Guido; Clarke, Ian N.; Lagergård, Teresa; Lukehart, Sheila A.; Unemo, Magnus; Shafer, William M.; Beasley, R. Palmer; Bergström, Tomas; Norberg, Peter; Davison, Andrew J.; Sharp, Paul M.; Hahn, Beatrice H.; Blomberg, Jonas

2013-01-01

The following series of concise summaries addresses the evolution of infectious agents in relation to sex in animals and humans from the perspective of three specific questions: (1) what have we learned about the likely origin and phylogeny, up to the establishment of the infectious agent in the genital econiche, including the relative frequency of its sexual transmission; (2) what further research is needed to provide additional knowledge on some of these evolutionary aspects; and (3) what evolutionary considerations might aid in providing novel approaches to the more practical clinical and public health issues facing us currently and in the future? PMID:21824167

An overview of the Valles Caldera National Preserve: the natural and cultural resources

USGS Publications Warehouse

Parmenter, Robert R.; Steffen, Anastasia; Allen, Craig D.; Kues, Barry S.; Kelley, Shari A.; Lueth, Virgil W.

2007-01-01

The Valles Caldera National Preserve is one of New Mexico’s natural wonders and a popular area for public recreation, sustainable natural resource production, and scientific research and education. Here, we provide a concise overview of the natural and cultural history of the Preserve, including descriptions of the ecosystems, flora and fauna. We note that, at the landscape scale, the Valles caldera appears to be spectacularly pristine; however, humans have extracted resources from the Preserve area for many centuries, resulting in localized impacts to forests, grasslands and watersheds. The Valles Caldera Trust is now charged with managing the Preserve and providing public access, while preserving and restoring these valuable public resources.

Flight Dynamics Analysis Branch End of Fiscal Year 2002 Report

NASA Technical Reports Server (NTRS)

Mangus, David (Editor); Mendelsohn, Chad (Editor); Starin, Scott (Editor); Stengle, Tom (Editor); Truong, Son (Editor)

2002-01-01

This report summarizes the major activities and accomplishments carried out by the Flight Dynamics Analysis Branch (FDAB), Code 572, in support of flight projects and technology development initiatives in Fiscal Year (FY) 2002. The report is intended to serve as a summary of the type of support carried out by the FDAB, as well as a concise reference of key accomplishments and mission experience derived from the various mission support roles. The primary focus of the FDAB is to provide expertise in the disciplines of flight dynamics including navigation, spacecraft trajectory design, attitude analysis, attitude determination and attitude control. The FDAB currently provides support for missions and technology development projects involving NASA, government, university, and private industry.

Mission Evaluation Room Intelligent Diagnostic and Analysis System (MIDAS)

NASA Technical Reports Server (NTRS)

Pack, Ginger L.; Falgout, Jane; Barcio, Joseph; Shnurer, Steve; Wadsworth, David; Flores, Louis

1994-01-01

The role of Mission Evaluation Room (MER) engineers is to provide engineering support during Space Shuttle missions, for Space Shuttle systems. These engineers are concerned with ensuring that the systems for which they are responsible function reliably, and as intended. The MER is a central facility from which engineers may work, in fulfilling this obligation. Engineers participate in real-time monitoring of shuttle telemetry data and provide a variety of analyses associated with the operation of the shuttle. The Johnson Space Center's Automation and Robotics Division is working to transfer advances in intelligent systems technology to NASA's operational environment. Specifically, the MER Intelligent Diagnostic and Analysis System (MIDAS) project provides MER engineers with software to assist them with monitoring, filtering and analyzing Shuttle telemetry data, during and after Shuttle missions. MIDAS off-loads to computers and software, the tasks of data gathering, filtering, and analysis, and provides the engineers with information which is in a more concise and usable form needed to support decision making and engineering evaluation. Engineers are then able to concentrate on more difficult problems as they arise. This paper describes some, but not all of the applications that have been developed for MER engineers, under the MIDAS Project. The sampling described herewith was selected to show the range of tasks that engineers must perform for mission support, and to show the various levels of automation that have been applied to assist their efforts.

A Stochastic Fractional Dynamics Model of Space-time Variability of Rain

NASA Technical Reports Server (NTRS)

Kundu, Prasun K.; Travis, James E.

2013-01-01

Rainfall varies in space and time in a highly irregular manner and is described naturally in terms of a stochastic process. A characteristic feature of rainfall statistics is that they depend strongly on the space-time scales over which rain data are averaged. A spectral model of precipitation has been developed based on a stochastic differential equation of fractional order for the point rain rate, that allows a concise description of the second moment statistics of rain at any prescribed space-time averaging scale. The model is thus capable of providing a unified description of the statistics of both radar and rain gauge data. The underlying dynamical equation can be expressed in terms of space-time derivatives of fractional orders that are adjusted together with other model parameters to fit the data. The form of the resulting spectrum gives the model adequate flexibility to capture the subtle interplay between the spatial and temporal scales of variability of rain but strongly constrains the predicted statistical behavior as a function of the averaging length and times scales. We test the model with radar and gauge data collected contemporaneously at the NASA TRMM ground validation sites located near Melbourne, Florida and in Kwajalein Atoll, Marshall Islands in the tropical Pacific. We estimate the parameters by tuning them to the second moment statistics of radar data. The model predictions are then found to fit the second moment statistics of the gauge data reasonably well without any further adjustment.

A concise guide for the determination of less-studied technology-critical elements (Nb, Ta, Ga, In, Ge, Te) by inductively coupled plasma mass spectrometry in environmental samples

NASA Astrophysics Data System (ADS)

Filella, Montserrat; Rodushkin, Ilia

2018-03-01

There is an increasing demand for analytical techniques able to measure so-called 'technology-critical elements', a set of chemical elements increasingly used in technological applications, in environmental matrices. Nowadays, inductively coupled plasma-mass spectrometry (ICP-MS) has become the technique of choice for measuring trace element concentrations. However, its application is often less straightforward than often assumed. The hints and drawbacks of ICP-MS application to the measurement of a set of less-studied technology-critical elements (Nb, Ta, Ga, In, Ge and Te) is discussed here and concise guidelines given.

Geophysical parameters from the analysis of laser ranging to Starlette

NASA Technical Reports Server (NTRS)

Schutz, B. E.; Shum, C. K.; Tapley, B. D.

1991-01-01

The University of Texas Center for Space Research (UT/CSR) research efforts covering the time period from August 1, 1990 through January 31, 1991 have concentrated on the following areas: (1) Laser Data Processing (more than 15 years of Starlette data (1975-90) have been processed and cataloged); (2) Seasonal Variation of Zonal Tides (observed Starlette time series has been compared with meteorological data-derived time series); (3) Ocean Tide Solutions . (error analysis has been performed using Starlette and other tide solutions); and (4) Lunar Deceleration (formulation to compute theoretical lunar deceleration has been verified and applied to several tidal solutions). Concise descriptions of research achievement for each of the above areas are given. Copies of abstracts for some of the publications and conference presentations are included in the appendices.

Repository-based software engineering program: Concept document

NASA Technical Reports Server (NTRS)

1992-01-01

This document provides the context for Repository-Based Software Engineering's (RBSE's) evolving functional and operational product requirements, and it is the parent document for development of detailed technical and management plans. When furnished, requirements documents will serve as the governing RBSE product specification. The RBSE Program Management Plan will define resources, schedules, and technical and organizational approaches to fulfilling the goals and objectives of this concept. The purpose of this document is to provide a concise overview of RBSE, describe the rationale for the RBSE Program, and define a clear, common vision for RBSE team members and customers. The document also provides the foundation for developing RBSE user and system requirements and a corresponding Program Management Plan. The concept is used to express the program mission to RBSE users and managers and to provide an exhibit for community review.

Life Sciences Implications of Lunar Surface Operations

NASA Technical Reports Server (NTRS)

Chappell, Steven P.; Norcross, Jason R.; Abercromby, Andrew F.; Gernhardt, Michael L.

2010-01-01

The purpose of this report is to document preliminary, predicted, life sciences implications of expected operational concepts for lunar surface extravehicular activity (EVA). Algorithms developed through simulation and testing in lunar analog environments were used to predict crew metabolic rates and ground reaction forces experienced during lunar EVA. Subsequently, the total metabolic energy consumption, the daily bone load stimulus, total oxygen needed, and other variables were calculated and provided to Human Research Program and Exploration Systems Mission Directorate stakeholders. To provide context to the modeling, the report includes an overview of some scenarios that have been considered. Concise descriptions of the analog testing and development of the algorithms are also provided. This document may be updated to remain current with evolving lunar or other planetary surface operations, assumptions and concepts, and to provide additional data and analyses collected during the ongoing analog research program.

Concept document of the repository-based software engineering program: A constructive appraisal

NASA Technical Reports Server (NTRS)

1992-01-01

A constructive appraisal of the Concept Document of the Repository-Based Software Engineering Program is provided. The Concept Document is designed to provide an overview of the Repository-Based Software Engineering (RBSE) Program. The Document should be brief and provide the context for reading subsequent requirements and product specifications. That is, all requirements to be developed should be traceable to the Concept Document. Applied Expertise's analysis of the Document was directed toward assuring that: (1) the Executive Summary provides a clear, concise, and comprehensive overview of the Concept (rewrite as necessary); (2) the sections of the Document make best use of the NASA 'Data Item Description' for concept documents; (3) the information contained in the Document provides a foundation for subsequent requirements; and (4) the document adequately: identifies the problem being addressed; articulates RBSE's specific role; specifies the unique aspects of the program; and identifies the nature and extent of the program's users.

Intake assessment of problematic use of medications in a chronic noncancer pain clinic

PubMed Central

Pink, Leah R; Smith, Andrew J; Peng, Philip WH; Galonski, Marilyn J; Tumber, Paul S; Evans, David; Gourlay, Doug L; Gordon, Lesley; Bellingham, Geoff A; Nijjar, Satnam S; Picard, Larry M; Gordon, Allan S

2012-01-01

BACKGROUND: The present article outlines the process of instituting an assessment of risk of problematic use of medications with new patients in an ambulatory chronic noncancer pain (CNCP) clinic. It is hoped that the authors’ experience through this iterative process will fill the gap in the literature by setting an example of an application of the ‘universal precautions’ approach to chronic pain management. OBJECTIVES: To assess the feasibility and utility of the addition of a new risk assessment process and to provide a snapshot of the risk of problematic use of medications in new patients presenting to a tertiary ambulatory clinic treating CNCP. METHODS: Charts for the first three months following the institution of an intake assessment for risk of problematic medication use were reviewed. Health care providers at the Wasser Pain Management Centre (Toronto, Ontario) were interviewed to discuss the preliminary findings and provide feedback about barriers to completing the intake assessments, as well as to identify the items that were clinically relevant and useful to their practice. RESULTS: Data were analyzed and examined for completeness. While some measures were considered to be particularly helpful, other items were regarded as repetitive, problematic or time consuming. Feedback was then incorporated into revisions of the risk assessment tool. DISCUSSION: Overall, it is feasible and useful to assess risk for problematic use of medications in new patients presenting to CNCP clinics. CONCLUSION: To facilitate the practice of assessment, the risk assessment tool at intake must be concise, clinically relevant and feasible given practitioner time constraints. PMID:22891193

Comets and life in the Universe

NASA Technical Reports Server (NTRS)

Oro, J.; Mills, T.; Lazcano, A.

1995-01-01

The notion that comets supplied the primitive Earth with the requisite chemical species for the process of chemical evolution, which is widely held to have led to the origin of life on Earth, has now gained considerable intellectual momentum since its first formulation in 1961. The role of comets in the Earth's biogenesis has been thoroughly addressed in the literature. At this time, in light of a few recent findings, we present here a concise review of this topic together with a brief discussion of the possible role of cometary material in the origin of life elsewhere in the Universe.

Optimal use of electrophysiological indicators of muscular effort and fatigue

NASA Technical Reports Server (NTRS)

Updike, O. L.

1981-01-01

Electromyograms (EMG) from working muscles convey information on effort and fatigue. Their application, e.g., to assess the demands of vehicle control tasks, is complicated by the cooperative action of sets of muscles, by both intrinsic and imposed filtering, and by numerous other sources of variation. Fourier analyses of these noise like signals offer one approach to interpretation; downward spectral shifts accompany fatigue. Techniques are being sought (in both time and frequency domains) for further condensing the wideband EMG signals, while retaining essential information, into a concise 'state vector' usable in comparing control system designs.

Human guidance of mobile robots in complex 3D environments using smart glasses

NASA Astrophysics Data System (ADS)

Kopinsky, Ryan; Sharma, Aneesh; Gupta, Nikhil; Ordonez, Camilo; Collins, Emmanuel; Barber, Daniel

2016-05-01

In order for humans to safely work alongside robots in the field, the human-robot (HR) interface, which enables bi-directional communication between human and robot, should be able to quickly and concisely express the robot's intentions and needs. While the robot operates mostly in autonomous mode, the human should be able to intervene to effectively guide the robot in complex, risky and/or highly uncertain scenarios. Using smart glasses such as Google Glass∗, we seek to develop an HR interface that aids in reducing interaction time and distractions during interaction with the robot.

Asynchronous discrete control of continuous processes

NASA Astrophysics Data System (ADS)

Kaliski, M. E.; Johnson, T. L.

1984-07-01

The research during this second contract year continued to deal with the development of sound theoretical models for asynchronous systems. Two criteria served to shape the research pursued: the first, that the developed models extend and generalize previously developed research for synchronous discrete control; the second, that the models explicitly address the question of how to incorporate system transition times into themselves. The following sections of this report concisely delineate this year's work. Our original proposal for this research identified four general tasks of investigation: (1.1) Analysis of Qualitative Properties of Asynchronous Hybrid Systems; (1.2) Acceptance and Control for Asynchronous Hybrid Systems.

compuGUT: An in silico platform for simulating intestinal fermentation

NASA Astrophysics Data System (ADS)

Moorthy, Arun S.; Eberl, Hermann J.

The microbiota inhabiting the colon and its effect on health is a topic of significant interest. In this paper, we describe the compuGUT - a simulation tool developed to assist in exploring interactions between intestinal microbiota and their environment. The primary numerical machinery is implemented in C, and the accessory scripts for loading and visualization are prepared in bash (LINUX) and R. SUNDIALS libraries are employed for numerical integration, and googleVis API for interactive visualization. Supplementary material includes a concise description of the underlying mathematical model, and detailed characterization of numerical errors and computing times associated with implementation parameters.

Analytical collisionless damping rate of geodesic acoustic mode

NASA Astrophysics Data System (ADS)

Ren, H.; Xu, X. Q.

2016-10-01

Collisionless damping of geodesic acoustic mode (GAM) is analytically investigated by considering the finite-orbit-width (FOW) resonance effect to the 3rd order in the gyro-kinetic equations. A concise and transparent expression for the damping rate is presented for the first time. Good agreement is found between the analytical damping rate and the previous TEMPEST simulation result (Xu 2008 et al Phys. Rev. Lett. 100 215001) for systematic q scans. Our result also shows that it is of sufficient accuracy and has to take into account the FOW effect to the 3rd order.

Self-study packets: an in-service strategy for today's emergency department.

PubMed

Macari, G H

1993-04-01

The self-study program has been a great success. Staff seized the opportunity for "hands-on," nonthreatening learning. The fear of asking questions and appearing less knowledgeable than peers in a group setting is removed, and new employees are grateful for the rapid accessibility of concise reference material. Everyone enjoys the freedom of fitting the in-service program into a routine day, rather than trying to adapt to a set time. Last, but not least, management reaps to the benefit of a program that satisfies the expectations of regulatory agencies and is virtually cost-free.

Effectiveness of focused source generation methods with consideration of interaural time and level difference.

PubMed

Zheng, Jianwen; Lu, Jing; Chen, Kai

2013-07-01

Several methods have been proposed for the generation of the focused source, usually a virtual monopole source positioned in between the loudspeaker array and the listener. The problem of pre-echoes of the common analytical methods has been noticed, and the most concise method to cope with this problem is the angular weight method. In this paper, the interaural time and level difference, which are well related to the localization cues of human auditory systems, will be used to further investigate the effectiveness of the focused source generation methods. It is demonstrated that the combination of angular weight method and the numerical pressure matching method has comparatively better performance in a given reconstructed area.

Diagnosis and Management of Budd Chiari Syndrome: An Update

DOE Office of Scientific and Technical Information (OSTI.GOV)

Copelan, Alexander, E-mail: alexander.copelan@beaumont.edu; Remer, Erick M., E-mail: remere1@ccf.org; Sands, Mark, E-mail: sandsm@ccf.org

Imaging plays a crucial role in the early detection and assessment of the extent of disease in Budd Chiari syndrome (BCS). Early diagnosis and intervention to mitigate hepatic congestion is vital to restoring hepatic function and alleviating portal hypertension. Interventional radiology serves a key role in the management of these patients. The interventionist should be knowledgeable of the clinical presentation as well as key imaging findings, which often dictate the approach to treatment. This article concisely reviews the etiology, pathophysiology, and clinical presentation of BCS and provides a detailed description of imaging and treatment options, particularly interventional management.

Situation-specific theories from the middle-range transitions theory.

PubMed

Im, Eun-Ok

2014-01-01

The purpose of this article was to analyze the theory development process of the situation-specific theories that were derived from the middle-range transitions theory. This analysis aims to provide directions for future development of situation-specific theories. First, transitions theory is concisely described with its history, goal, and major concepts. Then, the approach that was used to retrieve the situation-specific theories derived from transitions theory is described. Next, an analysis of 6 situation-specific theories is presented. Finally, 4 themes reflecting commonalities and variances in the theory development process are discussed with implications for future theoretical development.

Engaging Students with Active Thinking

NASA Astrophysics Data System (ADS)

Wieman, Carl E.

This Peer Review issue focuses on science and engaged learning. As any advertising executive or politician can tell you, engaging people is all about attitudes and beliefs, not abstract tacts. There is a lot we can learn from these professional communicators about how to effectively engage students. Far too often we, as educators, provide students with the content of science-often in the distilled formal representations that we have found to be the most concise and general-but fail to address students' own attitudes and beliefs. (Although heaven forbid that we should totally abandon reason and facts, as is typical in politics and advertising).

Nanoscale hybrid systems based on carbon nanotubes for biological sensing and control

PubMed Central

Cho, Youngtak; Shin, Narae; Kim, Daesan; Park, Jae Yeol

2017-01-01

This paper provides a concise review on the recent development of nanoscale hybrid systems based on carbon nanotubes (CNTs) for biological sensing and control. CNT-based hybrid systems have been intensively studied for versatile applications of biological interfaces such as sensing, cell therapy and tissue regeneration. Recent advances in nanobiotechnology not only enable the fabrication of highly sensitive biosensors at nanoscale but also allow the applications in the controls of cell growth and differentiation. This review describes the fabrication methods of such CNT-based hybrid systems and their applications in biosensing and cell controls. PMID:28188158

FIFTY YEARS IN PHYSICAL CHEMISTRY: Homage to Mentors, Methods, and Molecules

NASA Astrophysics Data System (ADS)

Herschbach, Dudley

2000-10-01

A nostalgic account is given of my scientific odyssey, recalling early encounters, some fateful, some just fun, with mentors, methods, and molecules. These include stories of my student years at Stanford, pursuing chemical kinetics with Harold Johnston; graduate study at Harvard, doing molecular spectroscopy with Bright Wilson; and fledgling faculty years at Berkeley, launching molecular beam studies of reaction dynamics. A few vignettes from my "ever after " era on the Harvard faculty emphasize thematic motivations or methods inviting further exploration. An Appendix provides a concise listing of colleagues in research and the topics we have pursued.

Comment on ``Numerics of the lattice Boltzmann method: Effects of collision models on the lattice Boltzmann simulations''

NASA Astrophysics Data System (ADS)

Karlin, I. V.; Succi, S.; Chikatamarla, S. S.

2011-12-01

Critical comments on the entropic lattice Boltzmann equation (ELBE), by Li-Shi Luo, Wei Liao, Xingwang Chen, Yan Peng, and Wei Zhang in Ref. , are based on simulations, which make use of a model that, despite being referred to as the ELBE by the authors, is in fact equivalent to the standard lattice Bhatnagar-Gross-Krook equation for low Mach number simulations. In this Comment, a concise review of the ELBE is provided and illustrated by means of a three-dimensional turbulent flow simulation, which highlights the subgrid features of the ELBE.

Planning for a data base system to support satellite conceptual design

NASA Technical Reports Server (NTRS)

Claydon, C. R.

1976-01-01

The conceptual design of an automated satellite design data base system is presented. The satellite catalog in the system includes data for all earth orbital satellites funded to the hardware stage for launch between 1970 and 1980, and provides a concise compilation of satellite capabilities and design parameters. The cost of satellite subsystems and components will be added to the base. Data elements are listed and discussed. Sensor and science and applications opportunities catalogs will be included in the data system. Capabilities of the BASIS storage, retrieval, and analysis system are used in the system design.

Is Your Telescope Tweeting?

NASA Astrophysics Data System (ADS)

Atkinson, Nancy

2009-05-01

Half of the world's population today was born after the Apollo Moon landings. The best way to reach this generation and get them excited about today's space exploration and astronomy news and events is through online social media, which are technologies that allow anyone to communicate with everyone. Twitter is a growing popular social media tool that uses short, 140 character "Tweets" to quickly and concisely convey updates on what you "are doing." With the right combination of information, personality and fun, telescopes and spacecraft are using Twitter for public outreach, providing important status updates while making the public feel like they are part of the mission.

Functionalization of P4 through Direct P-C Bond Formation.

PubMed

Borger, Jaap E; Ehlers, Andreas W; Slootweg, J Chris; Lammertsma, Koop

2017-09-04

Research on chlorine-free conversions of P 4 into organophosphorus compounds (OPCs) has a long track record, but methods that allow desirable, direct P-C bond formations have only recently emerged. These include the use of metal organyls, carbenes, carboradicals, and photochemical approaches. The versatile product scope enables the preparation of both industrially relevant organophosphorus compounds, as well as a broad range of intriguing new compound classes. Herein we provide a concise overview of recent breakthroughs and outline the acquired fundamental insights to aid future developments. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Paraxial ray optics cloaking.

PubMed

Choi, Joseph S; Howell, John C

2014-12-01

Despite much interest and progress in optical spatial cloaking, a three-dimensional (3D), transmitting, continuously multidirectional cloak in the visible regime has not yet been demonstrated. Here we experimentally demonstrate such a cloak using ray optics, albeit with some edge effects. Our device requires no new materials, uses isotropic off-the-shelf optics, scales easily to cloak arbitrarily large objects, and is as broadband as the choice of optical material, all of which have been challenges for current cloaking schemes. In addition, we provide a concise formalism that quantifies and produces perfect optical cloaks in the small-angle ('paraxial') limit.

Blood banking and transfusion medicine for the apheresis medicine practitioner.

PubMed

Jeffus, Susanne; Wehrli, Gay

2012-01-01

This article provides a concise overview of blood banking and transfusion medicine (BBTM) for the therapeutic apheresis medicine practitioner. It addresses the complete pathway from blood donor qualification to blood collection, to processing and storing blood components, to patient testing, to ordering blood components for therapeutic apheresis (TA) procedures, to preparing the component for transfusion, and finally to transfusion. The nurses, technologists, and physicians orchestrate these activities in concert to best serve patients undergoing TA procedures. Enhancing knowledge of these processes may improve the quality of patient care and the utilization of blood products. Copyright © 2012 Wiley Periodicals, Inc.

A new catalog of planetary maps

NASA Technical Reports Server (NTRS)

Batson, R. M.; Inge, J. L.

1991-01-01

A single, concise reference to all existing planetary maps, including lunar ones, is being prepared that will allow map users to identify and locate maps of their areas of interest. This will be the first such comprehensive listing of planetary maps. Although the USGS shows index maps on the collar of each map sheet, periodically publishes index maps of Mars, and provides informal listings of the USGS map database, no tabulation exists that identifies all planetary maps, including those published by DMA and other organizations. The catalog will consist of a booklet containing small-scale image maps with superimposed quadrangle boundaries and map data tabulations.

Water-soluble cationic conjugated polymers: response to electron-rich bioanalytes.

PubMed

Rochat, Sébastien; Swager, Timothy M

2013-11-27

We report the concise synthesis of a symmetrical monomer that provides a head-to-head pyridine building block for the preparation of cationic conjugated polymers. The obtained poly(pyridinium-phenylene) polymers display appealing properties such as high electron affinity, charge-transport upon n-doping, and optical response to electron-donating analytes. A simple assay for the optical detection of low micromolar amounts of a variety of analytes in aqueous solution was developed. In particular, caffeine could be measured at a 25 μM detection limit. The reported polymers are also suitable for layer-by-layer film formation.

Practical guidelines for feminist research in nursing.

PubMed

Im, Eun-Ok

2013-01-01

With increasing interests in oppressed groups, the number of feminist studies in nursing has steadily increased. Despite the increasing number of feminist studies, very few articles have been written to provide practical guidelines for feminist research in nursing. In this article, guidelines for feminist research in nursing are proposed on the basis of 3 previous feminist studies. First, characteristics of feminist research are concisely described. Then, the 3 studies that are the basis for the guidelines are described. Finally, practical guidelines for feminist nursing research are proposed on the basis of 10 idea categories related to issues/concerns from the 3 studies.

Penetration of nanoparticles and nanomaterials in the skin: fiction or reality?

PubMed

Baroli, Biancamaria

2010-01-01

The advent of nanotechnological products in the market, while holding great promise, is raising concerns in consumers. Therefore, this contribution will attempt to compare different particulate formulations and to answer whether their passive penetration into, and potential permeation through the skin may be possible or not. To this end, skin structure, composition, and penetration paths will be concisely reviewed. Parameters generally cited to affect skin absorption will be resumed and commented on from the perspective of potentially penetrating nanosized agents. These sections will provide the basis to understand what is fiction and what is reality.

Prospects for future climate change and the reasons for early action: critical review discussion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sylvia A. Edgerton; Mark Z. Jacobson; Alberto Ayala

2008-11-15

This paper presents a discussion of the 2008 A&WMA Critical Review (see Coal Abstracts Oct 2008 00143) by invited panellists and others who chose to comment. It includes written submissions and presentation of transcripts that were, in a few instances, edited for conciseness, to minimize redundancy, and to provide supporting and instructional citations. Substantial deviations from the intent of a discussant are unintentional and can be addressed in a follow-up letter to the journal. The invited discussants are: Dr. Mark Jacobson, Dr. Albertao Ayala, Dr Carol Whiteman and Dr Mark Trexlor. 4 figs.

Spacelab Data Processing Facility (SLDPF) quality assurance expert systems development

NASA Technical Reports Server (NTRS)

Kelly, Angelita C.; Basile, Lisa; Ames, Troy; Watson, Janice; Dallam, William

1987-01-01

Spacelab Data Processing Facility (SLDPF) expert system prototypes were developed to assist in the quality assurance of Spacelab and/or Attached Shuttle Payload (ASP) processed telemetry data. The SLDPF functions include the capturing, quality monitoring, processing, accounting, and forwarding of mission data to various user facilities. Prototypes for the two SLDPF functional elements, the Spacelab Output Processing System and the Spacelab Input Processing Element, are described. The prototypes have produced beneficial results including an increase in analyst productivity, a decrease in the burden of tedious analyses, the consistent evaluation of data, and the providing of concise historical records.

Spacelab Data Processing Facility (SLDPF) quality assurance expert systems development

NASA Technical Reports Server (NTRS)

Kelly, Angelita C.; Basile, Lisa; Ames, Troy; Watson, Janice; Dallam, William

1987-01-01

Spacelab Data Processing Facility (SLDPF) expert system prototypes have been developed to assist in the quality assurance of Spacelab and/or Attached Shuttle Payload (ASP) processed telemetry data. SLDPF functions include the capturing, quality monitoring, processing, accounting, and forwarding of mission data to various user facilities. Prototypes for the two SLDPF functional elements, the Spacelab Output Processing System and the Spacelab Input Processing Element, are described. The prototypes have produced beneficial results including an increase in analyst productivity, a decrease in the burden of tedious analyses, the consistent evaluation of data, and the providing of concise historical records.

Concise Review: Emerging Drugs Targeting Epithelial Cancer Stem-Like Cells.

PubMed

Ahmed, Mehreen; Chaudhari, Kritika; Babaei-Jadidi, Roya; Dekker, Lodewijk V; Shams Nateri, Abdolrahman

2017-04-01

Increasing evidence suggests that cancer cell populations contain a small proportion of cells that display stem-like cell properties and which may be responsible for overall tumor maintenance. These cancer stem-like cells (CSCs) appear to have unique tumor-initiating ability and innate survival mechanisms that allow them to resist cancer therapies, consequently promoting relapses. Selective targeting of CSCs may provide therapeutic benefit and several recent reports have indicated this may be possible. In this article, we review drugs targeting CSCs, in selected epithelial cell-derived cancers. Stem Cells 2017;35:839-850. © 2017 AlphaMed Press.

Theoretical study of mode evolution in active long tapered multimode fiber.

PubMed

Shi, Chen; Wang, Xiaolin; Zhou, Pu; Xu, Xiaojun; Lu, Qisheng

2016-08-22

A concise and effective model based on coupled mode theory to describe mode evolution in long tapered active fiber is presented in this manuscript. The mode coupling due to variation of core radius and slight perturbation have been analyzed and local gain with transverse spatial hole burning (TSHB) effect, loss and curvature have been taken into consideration in our model. On the base of this model, the mode evolution behaviors under different factors have been numerically investigated. Our model and results can provide instructive suggestions when designing long tapered fiber based laser and amplifiers.

Concise, stereodivergent and highly stereoselective synthesis of cis- and trans-2-substituted 3-hydroxypiperidines – development of a phosphite-driven cyclodehydration

PubMed Central

Westphal, Julia C

2014-01-01

Summary A concise (5 to 6 steps), stereodivergent, highly diastereoselective (dr up to >19:1 for both stereoisomers) and scalable synthesis (up to 14 g) of cis- and trans-2-substituted 3-piperidinols, a core motif in numerous bioactive compounds, is presented. This sequence allowed an efficient synthesis of the NK-1 inhibitor L-733,060 in 8 steps. Additionally, a cyclodehydration-realizing simple triethylphosphite as a substitute for triphenylphosphine is developed. Here the stoichiometric oxidized P(V)-byproduct (triethylphosphate) is easily removed during the work up through saponification overcoming separation difficulties usually associated to triphenylphosphine oxide. PMID:24605158

Therapeutic Alliance: A Concept for the Childbearing Season

PubMed Central

Doherty, Mary Ellen

2009-01-01

This analysis was conducted to describe the concept of therapeutic alliance and its appropriateness for health-care provider-client interactions during the childbearing season. The concept has been defined in other disciplines. A universal definition suggested a merging of efforts directed toward health. A simple and concise definition evolved, which is applicable to the childbearing season as well as to health-care encounters across the life span. This definition states: Therapeutic alliance is a process within a health-care provider-client interaction that is initiated by an identified need for positive client health-care behaviors, whereby both parties work together toward this goal with consideration of the client's current health status and developmental stage within the life span. PMID:20514120

The LLNA: A Brief Review of Recent Advances and Limitations

PubMed Central

Anderson, Stacey E.; Siegel, Paul D.; Meade, B. J.

2011-01-01

Allergic contact dermatitis is the second most commonly reported occupational illness, accounting for 10% to 15% of all occupational diseases. This highlights the importance of developing rapid and sensitive methods for hazard identification of chemical sensitizers. The murine local lymph node assay (LLNA) was developed and validated for the identification of low molecular weight sensitizing chemicals. It provides several benefits over other tests for sensitization because it provides a quantitative endpoint, dose-responsive data, and allows for prediction of potency. However, there are also several concerns with this assay including: levels of false positive responses, variability due to vehicle, and predictivity. This report serves as a concise review which briefly summarizes the progress, advances and limitations of the assay over the last decade. PMID:21747867

Perioperative Pain Management in Total Hip Arthroplasty: Korean Hip Society Guidelines

PubMed Central

Kim, Yeesuk; Cho, Hong-Man; Park, Kyung-Soon; Yoon, Pil Whan; Nho, Jae-Hwi; Kim, Sang-Min; Lee, Kyung-Jae; Moon, Kyong-Ho

2016-01-01

Effective perioperative pain management techniques and accelerated rehabilitation programs can improve health-related quality of life and functional status of patients after total hip arthroplasty. Traditionally, postoperative analgesia following arthroplasty was provided by intravenous patient-controlled analgesia or epidural analgesia. Recently, peripheral nerve blockade has emerged alternative analgesic approach. Multimodal analgesia strategy combines analgesics with different mechanisms of action to improve pain management. Intraoperative periarticular injection of multimodal drugs is one of the most important procedures in perioperative pain control for total hip arthroplasty. The goal of this review article is to provide a concise overview of the principles of multimodal pain management regimens as a practical guide for the perioperative pain management for total hip arthroplasty. PMID:27536639

A Unified Approach for Reporting ARM Measurement Uncertainties Technical Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Campos, E; Sisterson, DL

The Atmospheric Radiation Measurement (ARM) Climate Research Facility is observationally based, and quantifying the uncertainty of its measurements is critically important. With over 300 widely differing instruments providing over 2,500 datastreams, concise expression of measurement uncertainty is quite challenging. The ARM Facility currently provides data and supporting metadata (information about the data or data quality) to its users through a number of sources. Because the continued success of the ARM Facility depends on the known quality of its measurements, the Facility relies on instrument mentors and the ARM Data Quality Office (DQO) to ensure, assess, and report measurement quality. Therefore,more » an easily-accessible, well-articulated estimate of ARM measurement uncertainty is needed.« less

Effective use of remote sensing products in litigation

NASA Technical Reports Server (NTRS)

Jaynes, R. A.

1983-01-01

A boiled-down version of major legal principles affecting the admissibility of data and products from remote sensing devices is presented. It is suggested that enhancements or classifications of digital data (from scanning devices or from digitized aerial photography) be proffered as evidence in a fashion similar to the manner in which maps from photogrammetric techniques are introduced as evidence. Every effort should be made to illucidate the processes by which digital data are analytically treated or manipulated. Remote sensing expert witnesses should be practiced in providing concise and clear explanations of both data and methods. Special emphasis should be placed on being prepared to provide a detailed accounting of steps taken to calibrate and verify spectral characteristics with ground truth.

Nonequilibrium Green's function theory for nonadiabatic effects in quantum electron transport

NASA Astrophysics Data System (ADS)

Kershaw, Vincent F.; Kosov, Daniel S.

2017-12-01

We develop nonequilibrium Green's function-based transport theory, which includes effects of nonadiabatic nuclear motion in the calculation of the electric current in molecular junctions. Our approach is based on the separation of slow and fast time scales in the equations of motion for Green's functions by means of the Wigner representation. Time derivatives with respect to central time serve as a small parameter in the perturbative expansion enabling the computation of nonadiabatic corrections to molecular Green's functions. Consequently, we produce a series of analytic expressions for non-adiabatic electronic Green's functions (up to the second order in the central time derivatives), which depend not solely on the instantaneous molecular geometry but likewise on nuclear velocities and accelerations. An extended formula for electric current is derived which accounts for the non-adiabatic corrections. This theory is concisely illustrated by the calculations on a model molecular junction.

Nonequilibrium Green's function theory for nonadiabatic effects in quantum electron transport.

PubMed

Kershaw, Vincent F; Kosov, Daniel S

2017-12-14

We develop nonequilibrium Green's function-based transport theory, which includes effects of nonadiabatic nuclear motion in the calculation of the electric current in molecular junctions. Our approach is based on the separation of slow and fast time scales in the equations of motion for Green's functions by means of the Wigner representation. Time derivatives with respect to central time serve as a small parameter in the perturbative expansion enabling the computation of nonadiabatic corrections to molecular Green's functions. Consequently, we produce a series of analytic expressions for non-adiabatic electronic Green's functions (up to the second order in the central time derivatives), which depend not solely on the instantaneous molecular geometry but likewise on nuclear velocities and accelerations. An extended formula for electric current is derived which accounts for the non-adiabatic corrections. This theory is concisely illustrated by the calculations on a model molecular junction.

Fault diagnosis for analog circuits utilizing time-frequency features and improved VVRKFA

NASA Astrophysics Data System (ADS)

He, Wei; He, Yigang; Luo, Qiwu; Zhang, Chaolong

2018-04-01

This paper proposes a novel scheme for analog circuit fault diagnosis utilizing features extracted from the time-frequency representations of signals and an improved vector-valued regularized kernel function approximation (VVRKFA). First, the cross-wavelet transform is employed to yield the energy-phase distribution of the fault signals over the time and frequency domain. Since the distribution is high-dimensional, a supervised dimensionality reduction technique—the bilateral 2D linear discriminant analysis—is applied to build a concise feature set from the distributions. Finally, VVRKFA is utilized to locate the fault. In order to improve the classification performance, the quantum-behaved particle swarm optimization technique is employed to gradually tune the learning parameter of the VVRKFA classifier. The experimental results for the analog circuit faults classification have demonstrated that the proposed diagnosis scheme has an advantage over other approaches.

Plain Language to Communicate Physical Activity Information: A Website Content Analysis.

PubMed

Paige, Samantha R; Black, David R; Mattson, Marifran; Coster, Daniel C; Stellefson, Michael

2018-04-01

Plain language techniques are health literacy universal precautions intended to enhance health care system navigation and health outcomes. Physical activity (PA) is a popular topic on the Internet, yet it is unknown if information is communicated in plain language. This study examined how plain language techniques are included in PA websites, and if the use of plain language techniques varies according to search procedures (keyword, search engine) and website host source (government, commercial, educational/organizational). Three keywords ("physical activity," "fitness," and "exercise") were independently entered into three search engines (Google, Bing, and Yahoo) to locate a nonprobability sample of websites ( N = 61). Fourteen plain language techniques were coded within each website to examine content formatting, clarity and conciseness, and multimedia use. Approximately half ( M = 6.59; SD = 1.68) of the plain language techniques were included in each website. Keyword physical activity resulted in websites with fewer clear and concise plain language techniques ( p < .05), whereas fitness resulted in websites with more clear and concise techniques ( p < .01). Plain language techniques did not vary by search engine or the website host source. Accessing PA information that is easy to understand and behaviorally oriented may remain a challenge for users. Transdisciplinary collaborations are needed to optimize plain language techniques while communicating online PA information.

Microwave ablation of the liver: a description of lesion evolution over time and an investigation of the heat sink effect.

PubMed

Bhardwaj, N; Dormer, J; Ahmad, F; Strickland, A D; Gravante, G; West, K; Dennison, A R; Lloyd, D M

2011-12-01

Microwave ablation has been successfully used to treat unresectable liver tumours for many years. However, despite its widespread use, there seems to be a relative paucity of experimental data regarding lesion evolution and the effects of any surrounding vasculature on ablation morphology. The aim of this study was to investigate the principal pathological changes in the liver following microwave ablation, in particular the heat sink effect. In addition we carefully reviewed the available literature to provide an overview of all relevant pathological studies. Microwave ablation was carried out on male rats at various distances from the hilum. Histological (H&E) and immunocytochemical (caspase 3) analyses of the lesion were performed at various time points; 0, 4, 24, 48  hours, 2 weeks and 1 month. A literature review was carried out using Medline, Embase and the Cochrane database to identify all relevant histological studies. The lesion underwent complete coagulative necrosis and was extremely regular at the ablation edge with no evidence of any influence from surrounding blood vessels at all time points. H&E and caspase 3 results were consistent and microwave caused little collateral damage outside the intended ablation zone. This study suggests that microwave ablation is extremely concise and is minimally affected by the heat sink effect. Comparative investigations with other treatment modalities are required.

Concise Review: Tissue-Engineered Skin and Nerve Regeneration in Burn Treatment

PubMed Central

Blais, Mathieu; Parenteau-Bareil, Rémi; Cadau, Sébastien

2013-01-01

Burns not only destroy the barrier function of the skin but also alter the perceptions of pain, temperature, and touch. Different strategies have been developed over the years to cover deep and extensive burns with the ultimate goal of regenerating the barrier function of the epidermis while recovering an acceptable aesthetic aspect. However, patients often complain about a loss of skin sensation and even cutaneous chronic pain. Cutaneous nerve regeneration can occur from the nerve endings of the wound bed, but it is often compromised by scar formation or anarchic wound healing. Restoration of pain, temperature, and touch perceptions should now be a major challenge to solve in order to improve patients' quality of life. In addition, the cutaneous nerve network has been recently highlighted to play an important role in epidermal homeostasis and may be essential at least in the early phase of wound healing through the induction of neurogenic inflammation. Although the nerve regeneration process was studied largely in the context of nerve transections, very few studies have been aimed at developing strategies to improve it in the context of cutaneous wound healing. In this concise review, we provide a description of the characteristics of and current treatments for extensive burns, including tissue-engineered skin approaches to improve cutaneous nerve regeneration, and describe prospective uses for autologous skin-derived adult stem cells to enhance recovery of the skin's sense of touch. PMID:23734060

Developing web-based training for public health practitioners: what can we learn from a review of five disciplines?

PubMed Central

Ballew, Paula; Castro, Sarah; Claus, Julie; Kittur, Nupur; Brennan, Laura; Brownson, Ross C.

2013-01-01

During a time when governmental funding, resources and staff are decreasing and travel restrictions are increasing, attention to efficient methods of public health workforce training is essential. A literature review was conducted to inform the development and delivery of web-based trainings for public health practitioners. Literature was gathered and summarized from five disciplines: Information Technology, Health, Education, Business and Communications, following five research themes: benefits, barriers, retention, promotion and evaluation. As a result, a total of 138 articles relevant to web-based training design and implementation were identified. Key recommendations emerged, including the need to conduct formative research and evaluation, provide clear design and layout, concise content, interactivity, technical support, marketing and promotion and incentives. We conclude that there is limited application of web-based training in public health. This review offers an opportunity to learn from other disciplines. Web-based training methods may prove to be a key training strategy for reaching our public health workforce in the environment of limited resources. PMID:22987862

[History of homeopathy in Franconia].

PubMed

Dross, Fritz; Ruisinger, Marion Maria

2007-01-01

The research for this paper was initiated by an Erlangen exhibition project on the history of homeopathy on the occasion of the 250th anniversary of Samuel Hahnemann's birth in 2005. The founder of homeopathic medicine received his doctor of medicine degree at the University of Erlangen in 1779. As Hahnemann spent only four months in Erlangen, homeopathic physicians, patients and apothecaries in the region from Hahnemann's time until today were investigated. The aim was to provide a concise survey of the general problems in the history of homeopathy derived from regional cases which could be illustrated by objects suitable for an exhibition. Thus, the article is not only about the history of homeopathy in Northern Bavaria (Franconia), but also about a shift in the use of media and about doing science the other way round, viz. by starting at the presentation and ending with the sources. The outcome of the project was that most of the crucial topics of the history of homeopathy could be covered on a micro-historic scale: trials, pharmacy, hospital, patients, university, National Socialism.

PCB remediation in schools: a review.

PubMed

Brown, Kathleen W; Minegishi, Taeko; Cummiskey, Cynthia Campisano; Fragala, Matt A; Hartman, Ross; MacIntosh, David L

2016-02-01

Growing awareness of polychlorinated biphenyls (PCBs) in legacy caulk and other construction materials of schools has created a need for information on best practices to control human exposures and comply with applicable regulations. A concise review of approaches and techniques for management of building-related PCBs is the focus of this paper. Engineering and administrative controls that block pathways of PCB transport, dilute concentrations of PCBs in indoor air or other exposure media, or establish uses of building space that mitigate exposure can be effective initial responses to identification of PCBs in a building. Mitigation measures also provide time for school officials to plan a longer-term remediation strategy and to secure the necessary resources. These longer-term strategies typically involve removal of caulk or other primary sources of PCBs as well as nearby masonry or other materials contaminated with PCBs by the primary sources. The costs of managing PCB-containing building materials from assessment through ultimate disposal can be substantial. Optimizing the efficacy and cost-effectiveness of remediation programs requires aligning a thorough understanding of sources and exposure pathways with the most appropriate mitigation and abatement methods.

Microbial communities associated with human decomposition and their potential use as postmortem clocks.

PubMed

Finley, Sheree J; Benbow, M Eric; Javan, Gulnaz T

2015-05-01

Most forensic research that is used to better understand how to estimate the postmortem interval (PMI) entails the study of the physiochemical characteristics of decomposition and the effects that environmental factors have on the decomposition process. Forensic entomology exploits the life cycles of arthropods like Diptera (blow flies or flesh flies) and Coleoptera (beetles) deposited on the decaying carcass to determine PMI. Forensic taphonomy, from the Greek word taphos meaning burial, studies the creation of the fossils of decomposed cadavers to ascertain information as to the nature and time of death. Compared to other areas of taphonomy, there have been relatively few forensic science studies that have investigated the impact of human decomposition on the microbial changes occurring on or in a corpse or in the soil communities underneath a body. Such research may facilitate the critical determination of PMI. Therefore, the scope of this review is to provide a concise summary of the current progress in the newly emerging field of microbial diversity and the next-generation metagenomic sequencing approaches for assessing these communities in humans and in the soil beneath decomposing human.

Development and quality analysis of the Work Experience Measurement Scale (WEMS).

PubMed

Nilsson, Petra; Bringsén, Asa; Andersson, H Ingemar; Ejlertsson, Göran

2010-01-01

Instruments related to work are commonly illuminated from an ill-health perspective. The need for a concise and useable instrument in workplace health promotion governed the aim of this paper which is to present the development process and quality assessment of the Work Experience Measurement Scale (WEMS). A survey, using a questionnaire based on established theories regarding work and health, and a focus group study were performed in hospital settings in 2005 and 2006 respectively. A Principal Component Analysis (PCA) was used to statistically develop a model, and focus group interviews were made to compare quantitative and qualitative results for convergence and corroboration. The PCA resulted in a six factor model of dimensions containing items regarding management, reorganization, internal work experience, pressure of time, autonomy and supportive working conditions. In the analysis of the focus group study three themes appeared and their underlying content was compared to, and matched, with the dimensions of the PCA. The reliability, shown by weighted kappa values, ranged from 0.36 to 0.71, and adequate Cronbach's Alpha values of the dimensions were all above 0.7. The study validity, indicated by discriminant validity, with correlation values that ranged from 0.10 to 0.39, in relation to the content validity appeared to be good when the theoretical content of the WEMS was compared to the content of similar instruments. The WEMS presents a multidimensional picture of work experience. Its theoretical base and the psychometric properties give support for applicability and offer a possibility to measure trends in the work experience over time in health care settings. One intention of the WEMS is to stimulate the ability of organizations and the employees themselves to take action on improving their work experience. The conciseness of the instrument is intended to increase its usability.

A stochastic fractional dynamics model of space-time variability of rain

NASA Astrophysics Data System (ADS)

Kundu, Prasun K.; Travis, James E.

2013-09-01

varies in space and time in a highly irregular manner and is described naturally in terms of a stochastic process. A characteristic feature of rainfall statistics is that they depend strongly on the space-time scales over which rain data are averaged. A spectral model of precipitation has been developed based on a stochastic differential equation of fractional order for the point rain rate, which allows a concise description of the second moment statistics of rain at any prescribed space-time averaging scale. The model is thus capable of providing a unified description of the statistics of both radar and rain gauge data. The underlying dynamical equation can be expressed in terms of space-time derivatives of fractional orders that are adjusted together with other model parameters to fit the data. The form of the resulting spectrum gives the model adequate flexibility to capture the subtle interplay between the spatial and temporal scales of variability of rain but strongly constrains the predicted statistical behavior as a function of the averaging length and time scales. We test the model with radar and gauge data collected contemporaneously at the NASA TRMM ground validation sites located near Melbourne, Florida and on the Kwajalein Atoll, Marshall Islands in the tropical Pacific. We estimate the parameters by tuning them to fit the second moment statistics of radar data at the smaller spatiotemporal scales. The model predictions are then found to fit the second moment statistics of the gauge data reasonably well at these scales without any further adjustment.

MATERNAL ALCOHOL CONSUMPTION PRODUCING FETAL ALCOHOL SPECTRUM DISORDERS (FASD): QUANTITY, FREQUENCY, AND TIMING OF DRINKING

PubMed Central

May, Philip A.; Blankenship, Jason; Marais, Anna-Susan; Gossage, J. Phillip; Kalberg, Wendy O.; Joubert, Belinda; Cloete, Marise; Barnard, Ronel; De Vries, Marlene; Hasken, Julie; Robinson, Luther K.; Adnams, Colleen M.; Buckley, David; Manning, Melanie; Parry, Charles; Hoyme, H. Eugene; Tabachnick, Barbara; Seedat, Soraya

2013-01-01

Background Concise, accurate measures of maternal prenatal alcohol use are needed to better understand fetal alcohol spectrum disorders (FASD). Methods Measures of drinking by mothers of children with specific FASD diagnoses and mothers of randomly-selected controls are compared and also correlated with physical and cognitive/behavioral outcomes. Results Measures of maternal alcohol use can differentiate maternal drinking associated with FASD from that of controls and some from mothers of alcohol-exposed normals. Six variables that combine quantity and frequency concepts distinguish mothers of FASD children from normal controls. Alcohol use variables, when applied to each trimester and three months prior to pregnancy, provide insight on critical timing of exposure as well. Measures of drinking, especially bingeing, correlate significantly with increased child dysmorphology and negative cognitive/behavioral outcomes in children, especially low non-verbal IQ, poor attention, and behavioral problems. Logistic regression links (p<.001) first trimester drinking (vs. no drinking) with FASD, elevating FASD likelihood 12 times; first and second trimester drinking increases FASD outcomes 61 times; and drinking in all trimesters 65 times. Conversely, a similar regression (p=.008) indicates that drinking only in the first trimester makes the birth of a child with an FASD 5 times less likely than drinking in all trimesters. Conclusions There is significant variation in alcohol consumption both within and between diagnostic groupings of mothers bearing children diagnosed within the FASD continuum. Drinking measures are empirically identified and correlated with specific child outcomes. Alcohol use, especially heavy use, should be avoided throughout pregnancy. PMID:23932841

Maternal alcohol consumption producing fetal alcohol spectrum disorders (FASD): quantity, frequency, and timing of drinking.

PubMed

May, Philip A; Blankenship, Jason; Marais, Anna-Susan; Gossage, J Phillip; Kalberg, Wendy O; Joubert, Belinda; Cloete, Marise; Barnard, Ronel; De Vries, Marlene; Hasken, Julie; Robinson, Luther K; Adnams, Colleen M; Buckley, David; Manning, Melanie; Parry, Charles D H; Hoyme, H Eugene; Tabachnick, Barbara; Seedat, Soraya

2013-12-01

Concise, accurate measures of maternal prenatal alcohol use are needed to better understand fetal alcohol spectrum disorders (FASD). Measures of drinking by mothers of children with specific FASD diagnoses and mothers of randomly-selected controls are compared and also correlated with physical and cognitive/behavioral outcomes. Measures of maternal alcohol use can differentiate maternal drinking associated with FASD from that of controls and some from mothers of alcohol-exposed normals. Six variables that combine quantity and frequency concepts distinguish mothers of FASD children from normal controls. Alcohol use variables, when applied to each trimester and three months prior to pregnancy, provide insight on critical timing of exposure as well. Measures of drinking, especially bingeing, correlate significantly with increased child dysmorphology and negative cognitive/behavioral outcomes in children, especially low non-verbal IQ, poor attention, and behavioral problems. Logistic regression links (p<.001) first trimester drinking (vs. no drinking) with FASD, elevating FASD likelihood 12 times; first and second trimester drinking increases FASD outcomes 61 times; and drinking in all trimesters 65 times. Conversely, a similar regression (p=.008) indicates that drinking only in the first trimester makes the birth of a child with an FASD 5 times less likely than drinking in all trimesters. There is significant variation in alcohol consumption both within and between diagnostic groupings of mothers bearing children diagnosed within the FASD continuum. Drinking measures are empirically identified and correlated with specific child outcomes. Alcohol use, especially heavy use, should be avoided throughout pregnancy. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

Reported consent processes and demographics: a substudy of the INSIGHT Strategic Timing of AntiRetroviral Treatment trial

PubMed Central

Denning, Eileen; Sharma, Shweta; Smolskis, Mary; Touloumi, Giota; Walker, Sarah; Babiker, Abdel; Clewett, Megan; Emanuel, Ezekiel; Florence, Eric; Papadopoulos, Antonios; Sánchez, Adriana; Tavel, Jorge; Grady, Christine

2014-01-01

Objectives Efforts are needed to improve informed consent of participants in research. The Strategic Timing of AntiRetroviral Therapy (START) study provides a unique opportunity to study the effect of length and complexity of informed consent documents on understanding and satisfaction among geographically diverse participants. Methods Interested START sites were randomised to use either the standard consent form or the concise consent form for all of the site’s participants. Results A total of 4473 HIV-positive participants at 154 sites worldwide took part in the Informed Consent Substudy, with consent given in 11 primary languages. Most sites sent written information to potential participants in advance of clinic visits, usually including the consent form. At about half the sites, staff reported spending less than an hour per participant in the consent process. The vast majority of sites assessed participant understanding using informal nonspecific questions or clinical judgment. Conclusions These data reflect the interest of START research staff in evaluating the consent process and improving informed consent. The START Informed Consent Substudy is by far the largest study of informed consent intervention ever conducted. Its results have the potential to impact how consent forms are written around the world. PMID:25711320

Reported consent processes and demographics: a substudy of the INSIGHT Strategic Timing of AntiRetroviral Treatment (START) trial.

PubMed

Denning, E; Sharma, S; Smolskis, M; Touloumi, G; Walker, S; Babiker, A; Clewett, M; Emanuel, E; Florence, E; Papadopoulos, A; Sánchez, A; Tavel, J; Grady, C

2015-04-01

Efforts are needed to improve informed consent of participants in research. The Strategic Timing of AntiRetroviral Therapy (START) study provides a unique opportunity to study the effect of length and complexity of informed consent documents on understanding and satisfaction among geographically diverse participants. Interested START sites were randomized to use either the standard consent form or the concise consent form for all of the site's participants. A total of 4473 HIV-positive participants at 154 sites world-wide took part in the Informed Consent Substudy, with consent given in 11 primary languages. Most sites sent written information to potential participants in advance of clinic visits, usually including the consent form. At about half the sites, staff reported spending less than an hour per participant in the consent process. The vast majority of sites assessed participant understanding using informal nonspecific questions or clinical judgment. These data reflect the interest of START research staff in evaluating the consent process and improving informed consent. The START Informed Consent Substudy is by far the largest study of informed consent intervention ever conducted. Its results have the potential to impact how consent forms are written around the world. © 2015 British HIV Association.

Information flow and causality as rigorous notions ab initio

NASA Astrophysics Data System (ADS)

Liang, X. San

2016-11-01

Information flow or information transfer the widely applicable general physics notion can be rigorously derived from first principles, rather than axiomatically proposed as an ansatz. Its logical association with causality is firmly rooted in the dynamical system that lies beneath. The principle of nil causality that reads, an event is not causal to another if the evolution of the latter is independent of the former, which transfer entropy analysis and Granger causality test fail to verify in many situations, turns out to be a proven theorem here. Established in this study are the information flows among the components of time-discrete mappings and time-continuous dynamical systems, both deterministic and stochastic. They have been obtained explicitly in closed form, and put to applications with the benchmark systems such as the Kaplan-Yorke map, Rössler system, baker transformation, Hénon map, and stochastic potential flow. Besides unraveling the causal relations as expected from the respective systems, some of the applications show that the information flow structure underlying a complex trajectory pattern could be tractable. For linear systems, the resulting remarkably concise formula asserts analytically that causation implies correlation, while correlation does not imply causation, providing a mathematical basis for the long-standing philosophical debate over causation versus correlation.

Decomposed fuzzy systems and their application in direct adaptive fuzzy control.

PubMed

Hsueh, Yao-Chu; Su, Shun-Feng; Chen, Ming-Chang

2014-10-01

In this paper, a novel fuzzy structure termed as the decomposed fuzzy system (DFS) is proposed to act as the fuzzy approximator for adaptive fuzzy control systems. The proposed structure is to decompose each fuzzy variable into layers of fuzzy systems, and each layer is to characterize one traditional fuzzy set. Similar to forming fuzzy rules in traditional fuzzy systems, layers from different variables form the so-called component fuzzy systems. DFS is proposed to provide more adjustable parameters to facilitate possible adaptation in fuzzy rules, but without introducing a learning burden. It is because those component fuzzy systems are independent so that it can facilitate minimum distribution learning effects among component fuzzy systems. It can be seen from our experiments that even when the rule number increases, the learning time in terms of cycles is still almost constant. It can also be found that the function approximation capability and learning efficiency of the DFS are much better than that of the traditional fuzzy systems when employed in adaptive fuzzy control systems. Besides, in order to further reduce the computational burden, a simplified DFS is proposed in this paper to satisfy possible real time constraints required in many applications. From our simulation results, it can be seen that the simplified DFS can perform fairly with a more concise decomposition structure.

Mission and science activity scheduling language

NASA Technical Reports Server (NTRS)

Hull, Larry G.

1993-01-01

To support the distributed and complex operational scheduling required for future National Aeronautics and Space Administration (NASA) missions, a formal, textual language, the Scheduling Applications Interface Language (SAIL), has been developed. Increased geographic dispersion of investigators is leading to distributed mission and science activity planning, scheduling, and operations. SAIL is an innovation which supports the effective and efficient communication of scheduling information among physically dispersed applications in distributed scheduling environments. SAIL offers a clear, concise, unambiguous expression of scheduling information in a readable, hardware independent format. The language concept, syntax, and semantics incorporate language features found useful during five years of research and prototyping with scheduling languages in physically distributed environments. SAIL allows concise specification of mission and science activity plans in a format which promotes repetition and reuse.

The second demographic transition: A concise overview of its development

PubMed Central

Lesthaeghe, Ron

2014-01-01

This article gives a concise overview of the theoretical development of the concept of the “second demographic transition” since it was coined in 1986, its components, and its applicability, first to European populations and subsequently also to non-European societies as well. Both the demographic and the societal contrasts between the first demographic transition (FDT) and the second demographic transition (SDT) are highlighted. Then, the major criticisms of the SDT theory are outlined, and these issues are discussed in the light of the most recent developments in Europe, the United States, the Far East, and Latin America. It turns out that three major SDT patterns have developed and that these evolutions are contingent on much older systems of kinship and family organization. PMID:25453112

Crohn's disease: management in adults, children and young people - concise guidance .

PubMed

Tun, Gloria Sz; Cripps, Sarah; Lobo, Alan J

2018-06-01

Crohn's disease (CD) is a chronic inflammatory condition of the gastrointestinal tract. Individuals with CD present with acute inflammatory exacerbations as well as acute and chronic complications. Management requires specialist input from gastroenterologists, colorectal surgeons, nurse specialists and pharmacists as well as general and primary care physicians to allow appropriate selection of treatment options including surgery and rapid assessment and treatment of those with acute exacerbations. Monitoring of the individual and their medication is crucial in preventing and recognising complications including those associated with treatment. This concise guideline focuses on recommendations from National Institute for Health and Care Excellence (NICE) -Clinical -Guideline 152 (CG152) considered of key importance for implementation. © Royal College of Physicians 2018. All rights reserved.

Concise Review: Inner Ear Stem Cells—An Oxymoron, But Why?

PubMed Central

Ronaghi, Mohammad; Nasr, Marjan; Heller, Stefan

2012-01-01

Hearing loss, caused by irreversible loss of cochlear sensory hair cells, affects millions of patients worldwide. In this concise review, we examine the conundrum of inner ear stem cells, which obviously are present in the inner ear sensory epithelia of nonmammalian vertebrates, giving these ears the ability to functionally recover even from repetitive ototoxic insults. Despite the inability of the mammalian inner ear to regenerate lost hair cells, there is evidence for cells with regenerative capacity because stem cells can be isolated from vestibular sensory epithelia and from the neonatal cochlea. Challenges and recent progress toward identification of the intrinsic and extrinsic signaling pathways that could be used to re-establish stemness in the mammalian organ of Corti are discussed. PMID:22102534

Concise expression of a classical radiation spectrum

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, C.

1993-06-01

In this paper we present a concise expression of the classical electromagnetic radiation spectrum of a moving charge. It is shown to be equivalent to the often used and much more complicated form derived from the Lienard-Wiechert potentials when the observation distance [ital R] satisfies the condition [ital R][much gt][gamma][lambda]. The expression reveals a relationship between the radiation spectrum and the motion of the radiation source. It also forms the basis of an efficient computing approach, which is of practical value in numerical calculations of the spectral output of accelerated charges. The advantages of this approach for analytical and numericalmore » applications are discussed and the bending-magnet synchrotron radiation spectrum is calculated according to the approach.« less

Feasibility study of an Integrated Program for Aerospace vehicle Design (IPAD). Volume 1B: Concise review

NASA Technical Reports Server (NTRS)

Miller, R. E., Jr.; Southall, J. W.; Kawaguchi, A. S.; Redhed, D. D.

1973-01-01

Reports on the design process, support of the design process, IPAD System design catalog of IPAD technical program elements, IPAD System development and operation, and IPAD benefits and impact are concisely reviewed. The approach used to define the design is described. Major activities performed during the product development cycle are identified. The computer system requirements necessary to support the design process are given as computational requirements of the host system, technical program elements and system features. The IPAD computer system design is presented as concepts, a functional description and an organizational diagram of its major components. The cost and schedules and a three phase plan for IPAD implementation are presented. The benefits and impact of IPAD technology are discussed.

Normalizing the causality between time series.

PubMed

Liang, X San

2015-08-01

Recently, a rigorous yet concise formula was derived to evaluate information flow, and hence the causality in a quantitative sense, between time series. To assess the importance of a resulting causality, it needs to be normalized. The normalization is achieved through distinguishing a Lyapunov exponent-like, one-dimensional phase-space stretching rate and a noise-to-signal ratio from the rate of information flow in the balance of the marginal entropy evolution of the flow recipient. It is verified with autoregressive models and applied to a real financial analysis problem. An unusually strong one-way causality is identified from IBM (International Business Machines Corporation) to GE (General Electric Company) in their early era, revealing to us an old story, which has almost faded into oblivion, about "Seven Dwarfs" competing with a giant for the mainframe computer market.

Normalizing the causality between time series

NASA Astrophysics Data System (ADS)

Liang, X. San

2015-08-01

Recently, a rigorous yet concise formula was derived to evaluate information flow, and hence the causality in a quantitative sense, between time series. To assess the importance of a resulting causality, it needs to be normalized. The normalization is achieved through distinguishing a Lyapunov exponent-like, one-dimensional phase-space stretching rate and a noise-to-signal ratio from the rate of information flow in the balance of the marginal entropy evolution of the flow recipient. It is verified with autoregressive models and applied to a real financial analysis problem. An unusually strong one-way causality is identified from IBM (International Business Machines Corporation) to GE (General Electric Company) in their early era, revealing to us an old story, which has almost faded into oblivion, about "Seven Dwarfs" competing with a giant for the mainframe computer market.

Fatigue loading history reconstruction based on the rain-flow technique

NASA Technical Reports Server (NTRS)

Khosrovaneh, A. K.; Dowling, N. E.

1989-01-01

Methods are considered for reducing a non-random fatigue loading history to a concise description and then for reconstructing a time history similar to the original. In particular, three methods of reconstruction based on a rain-flow cycle counting matrix are presented. A rain-flow matrix consists of the numbers of cycles at various peak and valley combinations. Two methods are based on a two dimensional rain-flow matrix, and the third on a three dimensional rain-flow matrix. Histories reconstructed by any of these methods produce a rain-flow matrix identical to that of the original history, and as a result the resulting time history is expected to produce a fatigue life similar to that for the original. The procedures described allow lengthy loading histories to be stored in compact form.

Flight Dynamics Analysis Branch End of Fiscal Year 1999 Report

NASA Technical Reports Server (NTRS)

Stengle, T.; Flores-Amaya, F.

2000-01-01

This report summarizes the major activities and accomplishments carried out by the Flight Dynamics Analysis Branch (FDAB), Code 572, in support of flight projects and technology development initiatives in Fiscal Year (FY) 1999. The report is intended to serve as a summary of the type of support carried out by the FDAB, as well as a concise reference of key analysis results and mission experience derived from the various mission support roles. The primary focus of the FDAB is to provide expertise in the discipline of flight dynamics, which involves spacecraft trajectory (orbit) and attitude analysis, as well as orbit and attitude determination and control. The FDAB currently provides support for missions involving NASA, government, university, and commercial space missions, at various stages in the mission life cycle.

Flight Dynamics Analysis Branch 2005 Technical Highlights

NASA Technical Reports Server (NTRS)

2005-01-01

This report summarizes the major activities and accomplishments carried out by the Flight Dynamics Analysis Branch (FDAB), Code 595, in support of flight projects and technology development initiatives in Fiscal Year (FY) 2005. The report is intended to serve as a summary of the type of support carried out by the FDAB, as well as a concise reference of key accomplishments and mission experience derived from the various mission support roles. The primary focus of the FDAB is to provide expertise in the disciplines of flight dynamics including spacecraft navigation (autonomous and ground based); spacecraft trajectory design and maneuver planning; attitude analysis; attitude determination and sensor calibration; and attitude control subsystem (ACS) analysis and design. The FDAB currently provides support for missions and technology development projects involving NASA, other government agencies, academia, and private industry.

Nondestructive evaluation technique guide

NASA Technical Reports Server (NTRS)

Vary, A.

1973-01-01

A total of 70 individual nondestructive evaluation (NDE) techniques are described. Information is presented that permits ease of comparison of the merits and limitations of each technique with respect to various NDE problems. An NDE technique classification system is presented. It is based on the system that was adopted by the National Materials Advisory Board (NMAB). The classification system presented follows the NMAB system closely with the exception of additional categories that have been added to cover more advanced techniques presently in use. The rationale of the technique is explained. The format provides for a concise description of each technique, the physical principles involved, objectives of interrogation, example applications, limitations of each technique, a schematic illustration, and key reference material. Cross-index tabulations are also provided so that particular NDE problems can be referred to appropriate techniques.

Technical manual for manufacturing autologous fibrin tissue adhesive.

PubMed

Park, J J; Cintron, J R; Siedentop, K H; Orsay, C P; Pearl, R K; Nelson, R L; Abcarian, H

1999-10-01

The aim of this article is to provide a concise and simple technical manual for manufacturing autologous fibrin tissue adhesive derived from the precipitation of fibrinogen using a combination of ethanol and freezing for surgery. All materials and equipment needed to manufacture ethanol-based autologous fibrin tissue adhesive are listed. In addition, step-by-step instructions are provided to allow for easy and rapid fibrin adhesive production. Ethanol-based autologous fibrin tissue adhesive can be manufactured in under 60 minutes. Furthermore, at our institution the startup cost for manufacturing ethanol-based autologous fibrin tissue adhesive was under $2,500.00. Ethanol-based autologous fibrin tissue adhesive is a safe, reliable, and easily manufactured autologous fibrin tissue adhesive that can be made by a trained technician in any blood bank, pharmacy, or surgical laboratory.

Big Data Analytics with Datalog Queries on Spark.

PubMed

Shkapsky, Alexander; Yang, Mohan; Interlandi, Matteo; Chiu, Hsuan; Condie, Tyson; Zaniolo, Carlo

2016-01-01

There is great interest in exploiting the opportunity provided by cloud computing platforms for large-scale analytics. Among these platforms, Apache Spark is growing in popularity for machine learning and graph analytics. Developing efficient complex analytics in Spark requires deep understanding of both the algorithm at hand and the Spark API or subsystem APIs (e.g., Spark SQL, GraphX). Our BigDatalog system addresses the problem by providing concise declarative specification of complex queries amenable to efficient evaluation. Towards this goal, we propose compilation and optimization techniques that tackle the important problem of efficiently supporting recursion in Spark. We perform an experimental comparison with other state-of-the-art large-scale Datalog systems and verify the efficacy of our techniques and effectiveness of Spark in supporting Datalog-based analytics.

Big Data Analytics with Datalog Queries on Spark

PubMed Central

Shkapsky, Alexander; Yang, Mohan; Interlandi, Matteo; Chiu, Hsuan; Condie, Tyson; Zaniolo, Carlo

2017-01-01

There is great interest in exploiting the opportunity provided by cloud computing platforms for large-scale analytics. Among these platforms, Apache Spark is growing in popularity for machine learning and graph analytics. Developing efficient complex analytics in Spark requires deep understanding of both the algorithm at hand and the Spark API or subsystem APIs (e.g., Spark SQL, GraphX). Our BigDatalog system addresses the problem by providing concise declarative specification of complex queries amenable to efficient evaluation. Towards this goal, we propose compilation and optimization techniques that tackle the important problem of efficiently supporting recursion in Spark. We perform an experimental comparison with other state-of-the-art large-scale Datalog systems and verify the efficacy of our techniques and effectiveness of Spark in supporting Datalog-based analytics. PMID:28626296

An Analytical State Transition Matrix for Orbits Perturbed by an Oblate Spheroid

NASA Technical Reports Server (NTRS)

Mueller, A. C.

1977-01-01

An analytical state transition matrix and its inverse, which include the short period and secular effects of the second zonal harmonic, were developed from the nonsingular PS satellite theory. The fact that the independent variable in the PS theory is not time is in no respect disadvantageous, since any explicit analytical solution must be expressed in the true or eccentric anomaly. This is shown to be the case for the simple conic matrix. The PS theory allows for a concise, accurate, and algorithmically simple state transition matrix. The improvement over the conic matrix ranges from 2 to 4 digits accuracy.