Examples of actions that improve partnering cooperation among the participants of construction projects

NASA Astrophysics Data System (ADS)

Radziszewska-Zielina, E.; Szewczyk, B.

2017-10-01

The aim of the article is to present examples of actions that can be undertaken in order to improve partnering cooperation in construction projects. These actions are a practical supplementation to the previously developed fuzzy system of controlling partnering relations in construction projects. The actions relate to 18 parameters of partnering relations that describe cooperation between a general contractor or a company that manages the project and four other participants: the contractors (subcontractors), the designer, the material and equipment suppliers and the real estate developer. The actions have been listed based on a review of subject literature, self-analysis, as well as interviews with participants of construction projects. They can provide examples of good practices that maintain partnering cooperation at a high level. Good cooperation, in turn, translates into a better performance of the project.

Mathematical Adventures in Role Play

ERIC Educational Resources Information Center

Tyce, Constance

2002-01-01

The provision of role play is vital in every early years setting. It provides opportunities for the development of all areas of learning. With careful thought and planning, all role play situations can provide children with mathematical adventures. Many examples of good quality role play had been observed in a variety of settings throughout…

Einsatz hydrogeochemischer Modelle in der Wasseraufbereitung

NASA Astrophysics Data System (ADS)

Wisotzky, Frank

2012-09-01

As part of a model-data investigation project, results of several water treatment studies were compared with hydrochemical models. The models used comparable hydrogeological reaction types that occur within aquifers and water treatment processes. They were tested on 3 different examples of water softening, de-nitrification and iron removal. Comparison of simulated and measured water chemical dynamics showed good agreement. In addition to mixing and formation of complexes, de-acidification and de-carbonisation processes were reproduced in the first example. The second example investigated de-nitrification in a straw filter and in a water plant filter with subsequent aeration. The third example showed iron removal where reactions with partially combusted dolomite were simulated with a computer model. All simulations showed good agreement with the observed data. The models have the advantage of yielding parameter results that are difficult to measure. This includes nitrogen gas release and the content of reacted and degradable organic substances. These tools may help to provide better insights into water treatment reactions.

Students' Good Reasons.

ERIC Educational Resources Information Center

Alro, Helle; Skovsmose, Ole

1996-01-01

Provides examples and a discussion of the Inquiry Cooperation Model (ICM). The ICM is a way of describing a pattern of communicative cooperation between teacher and students. It tries to develop students' preconceptions into mathematical competence. Contains 15 references. (DDR)

Examples of Holistic Good Practices in Promoting and Protecting Mental Health in the Workplace: Current and Future Challenges.

PubMed

Sivris, Kelly C; Leka, Stavroula

2015-12-01

While attention has been paid to physical risks in the work environment and the promotion of individual employee health, mental health protection and promotion have received much less focus. Psychosocial risk management has not yet been fully incorporated in such efforts. This paper presents good practices in promoting mental health in the workplace in line with World Health Organization (WHO) guidance by identifying barriers, opportunities, and the way forward in this area. Semistructured interviews were conducted with 17 experts who were selected on the basis of their knowledge and expertise in relation to good practice identified tools. Interviewees were asked to evaluate the approaches on the basis of the WHO model for healthy workplaces. The examples of good practice for Workplace Mental Health Promotion (WMHP) are in line with the principles and the five keys of the WHO model. They support the third objective of the WHO comprehensive mental health action plan 2013-2020 for multisectoral implementation of WMHP strategies. Examples of good practice include the engagement of all stakeholders and representatives, science-driven practice, dissemination of good practice, continual improvement, and evaluation. Actions to inform policies/legislation, promote education on psychosocial risks, and provide better evidence were suggested for higher WMHP success. The study identified commonalities in good practice approaches in different countries and stressed the importance of a strong policy and enforcement framework as well as organizational responsibility for WMHP. For progress to be achieved in this area, a holistic and multidisciplinary approach was unanimously suggested as a way to successful implementation.

Examples of Holistic Good Practices in Promoting and Protecting Mental Health in the Workplace: Current and Future Challenges

PubMed Central

Sivris, Kelly C.; Leka, Stavroula

2015-01-01

Background While attention has been paid to physical risks in the work environment and the promotion of individual employee health, mental health protection and promotion have received much less focus. Psychosocial risk management has not yet been fully incorporated in such efforts. This paper presents good practices in promoting mental health in the workplace in line with World Health Organization (WHO) guidance by identifying barriers, opportunities, and the way forward in this area. Methods Semistructured interviews were conducted with 17 experts who were selected on the basis of their knowledge and expertise in relation to good practice identified tools. Interviewees were asked to evaluate the approaches on the basis of the WHO model for healthy workplaces. Results The examples of good practice for Workplace Mental Health Promotion (WMHP) are in line with the principles and the five keys of the WHO model. They support the third objective of the WHO comprehensive mental health action plan 2013–2020 for multisectoral implementation of WMHP strategies. Examples of good practice include the engagement of all stakeholders and representatives, science-driven practice, dissemination of good practice, continual improvement, and evaluation. Actions to inform policies/legislation, promote education on psychosocial risks, and provide better evidence were suggested for higher WMHP success. Conclusion The study identified commonalities in good practice approaches in different countries and stressed the importance of a strong policy and enforcement framework as well as organizational responsibility for WMHP. For progress to be achieved in this area, a holistic and multidisciplinary approach was unanimously suggested as a way to successful implementation. PMID:26929841

[Study of genuineness based on changes of ancient herbal origin--taking Astragalus membranaceus and Salvia miltiorrhiza as examples].

PubMed

Zhan, Zhi-Lai; Deng, Ai-Ping; Peng, Hua-Sheng; Zhang, Xiao-Bo; Guo, Lan-Ping; Huang, Lu-Qi

2016-09-01

Basically, Dao-di hers are produced in specific area which has a long history, good quality, good medicine, curative effect. However genuine medicinal material area in history is not static, this makes the establishment of genuine medicinal material origin and the in-depth research be very difficult. This paper has profoundly analyzed the origin of different historical periods taking Astragalus membranaceus and Salvia miltiorrhiza as examples, and then summarized the reasons of herbal origin changes from the humanities, social and natural three aspects. This paper provides a basis for establishment and the further research of high-quality genuine producing area. Copyright© by the Chinese Pharmaceutical Association.

[Identification of Good-Practice Projects in Promoting Physical Activity - Methods, Pitfalls and Sampled Outcomes].

PubMed

Henn, Annette; Karger, Claudia; Wöhlken, Katrin; Meier, Diana; Ungerer-Röhrich, Ulrike; Graf, Christine; Woll, Alexander

2017-03-01

The aim of this paper is to identify and show examples of good practice of public health promotion. For this, uniform quality criteria were worked out under consideration of national and international scientific literature.For the identification of examples of good practice, a comparison of different quality criteria was carried out and combined with each other in a first step. In the following step, examples of good practice were identified after a comprehensive search. The choice of the "good-practice" projects is exemplary and lays no claim to completeness.6 main quality criteria (QC) of programs promoting physical activity could be identified in the national and international context. The analysis showed altogether 10 projects which can exemplarily be classified as examples of good practice of the target groups of children and teenagers, adults, older people and people with pre-existing illnesses. These projects, however, show major differences in their (methodological) quality.The analysis reports a lack of "Good-Practice" examples. Deficits lie mainly in documentation and sustainability. Because of incomplete documentation, an assessment as a "Good-Practice" example is only possible to a limited extent; a lot of information, particularly in the evaluation, is missing. © Georg Thieme Verlag KG Stuttgart · New York.

Teaching and Learning Communication, Language and Literacy

ERIC Educational Resources Information Center

Browne, Ann

2007-01-01

In this book, Ann Browne draws on research findings and good practice to provide practical and guidance about working with young children aged 3-5 years in nursery and reception classes. The author covers all of the key theoretical issues, providing a wealth of classroom examples. Practical suggestions for activities and resources include ways of…

Safety in surgery: is selection the missing link?

PubMed

Paice, Alistair G; Aggarwal, Rajesh; Darzi, Ara

2010-09-01

Health care providers comprise an example of a "high risk organization." Safety failings within these organizations have the potential to cause significant public harm. Significant safety improvements in other high risk organizations such as the aviation industry have led to the concept of a high reliability organization (HRO)--a high risk organization that has enjoyed a prolonged safety record. A strong organizational culture is common to all successful HROs, encompassing powerful systems of selection and training. Aircrew selection processes provide a good example of this and are examined in detail in this article using the Royal Air Force process as an example. If the lessons of successful HROs are to be applied to health care organizations, candidate selection to specialties such as surgery must become more objective and robust. Other HROs can provide valuable lessons in how this may be approached.

Keep on Trucking: An Entrepreneurial Approach to Intratheater Airlift

DTIC Science & Technology

2013-02-14

yet they must all remain effective in order to stay in business.50 Figure 3. Commercial Distribution Example: Walmart 10 As one of the...world’s largest corporations, Walmart provides a good example of an entrepreneurial logistics system (Figure 3). Like the deployed Air Force component, it...is a fleet owner, a distributor, and a retail location operator.51 While Walmart uses trucks, the AMD schedules aircraft as the primary delivery

Be a Healthy Role Model for Children: 10 Tips for Setting Good Examples

MedlinePlus

... model for children 10 tips for setting good examples You are the most important influence on your ... make mealtime a family time! 1 show by example Eat vegetables, fruits, and whole grains with meals ...

Elements of a Research Report.

ERIC Educational Resources Information Center

Schurter, William J.

This guide for writing research or technical reports discusses eleven basic elements of such reports and provides examples of "good" and "bad" wordings. These elements are the title, problem statement, purpose statement, need statement, hypothesis, assumptions, procedures, limitations, terminology, conclusion and recommendations. This guide is…

Teaching with Games: Online Resources and Examples for Entry Level Courses

NASA Astrophysics Data System (ADS)

Teed, R.; Manduca, C.

2004-12-01

Using games to teach introductory geoscience can motivate students to enthusiastically learn material that they might otherwise condemn as "boring". A good educational game is one that immerses the players in the material and engages them for as long as it takes to master that material. There are some good geoscience games already available, but instructors can also create their own, suitable to their students and the content that they are teaching. Game-Based Learning is a module on the Starting Point website for faculty teaching entry level geosciences. It assists faculty in using games in their teaching by providing a description of the features of game-based learning, why you would use it, how to use games to teach geoscience, examples, and references. Other issues discussed include the development of video games for teaching, having your students create educational games, what makes a good game, handling competition in the classroom, and grading. The examples include descriptions of and rules for a GPS treasure hunt, a geology quiz show, and an earthquake game, as well as links to several online geological video games, and advice on how to design a paleontology board game. Starting Point is intended to help both experienced faculty and new instructors meet the challenge of teaching introductory geoscience classes, including environmental science and oceanography as well as more traditional geology classes. For many students, these classes are both the first and the last college-level science class that they will ever take. They need to learn enough about the Earth in that one class to sustain them for many decades as voters, consumers, and sometimes even as teachers. Starting Point is produced by a group of authors working with the Science Education Resource Center. It contains dozens of detailed examples categorized by geoscience topic with advice about using them and assessing learning. Each example is linked to one of many modules, such as Game-Based Learning, Interactive Lectures, or Using an Earth History Approach. These modules describe teaching tools and techniques, provide examples and advice about using them in an introductory geoscience class, and give instructors details on how to create their own exercises.

Standard and goodness-of-fit parameter estimation methods for the three-parameter lognormal distribution

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kane, V.E.

1982-01-01

A class of goodness-of-fit estimators is found to provide a useful alternative in certain situations to the standard maximum likelihood method which has some undesirable estimation characteristics for estimation from the three-parameter lognormal distribution. The class of goodness-of-fit tests considered include the Shapiro-Wilk and Filliben tests which reduce to a weighted linear combination of the order statistics that can be maximized in estimation problems. The weighted order statistic estimators are compared to the standard procedures in Monte Carlo simulations. Robustness of the procedures are examined and example data sets analyzed.

A Guide for Submissions to the "JEE" Content Section

ERIC Educational Resources Information Center

Holmes, Jessica; Rothschild, Casey; Setterfield, Mark

2009-01-01

The authors provide a guide to the thinking of the editorial collective for the Content section of the "Journal of Economic Education (JEE)". They discuss the type of papers they are looking for, what in their view constitutes a good paper, and how their review process works. They also provide some examples of what works (and what does not).…

20 CFR 220.52 - Failure to appear at a consultative examination.

Code of Federal Regulations, 2010 CFR

2010-04-01

... not have good reason for failing or refusing to take part in a consultative examination or test which... good reason for failure to appear, another examination or test will be scheduled. (b) Examples of good reasons for failure to appear. Some examples of good reasons for not going to a scheduled examination or...

Baseball Physics: A New Mechanics Lab

ERIC Educational Resources Information Center

Wagoner, Kasey; Flanagan, Daniel

2018-01-01

The game of baseball provides an interesting laboratory for experimenting with mechanical phenomena (there are many good examples in "The Physics Teacher," available on Professor Alan Nathan's website, and discussed in "Physics of Baseball & Softball"). We have developed a lab, for an introductory-level physics course, that…

On the Origins of Readers' Outcome Preferences

ERIC Educational Resources Information Center

Gerrig, Richard J.; Bagelmann, Kelsey A.; Mumper, Micah L.

2016-01-01

Narratives often provide readers with opportunities to encode their preferences for particular outcomes. Our project examines some origins of such outcome preferences. For example, past literature suggests that readers tend to prefer positive outcomes for "good" characters and negative outcomes for "bad" characters. To extend…

Writing Multiple Choice Outcome Questions to Assess Knowledge and Competence.

PubMed

Brady, Erik D

2015-11-01

Few articles contemplate the need for good guidance in question item-writing in the continuing education (CE) space. Although many of the core principles of sound item design translate to the CE health education team, the need exists for specific examples for nurse educators that clearly describe how to measure changes in competence and knowledge using multiple choice items. In this article, some keys points and specific examples for nursing CE providers are shared. Copyright 2015, SLACK Incorporated.

Centralized vs. decentralized child mental health services.

PubMed

Adams, M S

1977-09-01

One of the basic tenets of the Community Mental Health Center movement is that services should be provided in the consumers' community. Various centers across the country have attempted to do this in either a centralized or decentralized fashion. Historically, most health services have been provided centrally, a good example being the traditional general hospital with its centralized medical services. Over the years, some of these services have become decentralized to take the form of local health centers, health maintenance organizations, community clinics, etc, and now various large mental health centers are also being broken down into smaller community units. An example of each type of mental health facility is delineated here.

Evaluating Research Articles from Start to Finish.

ERIC Educational Resources Information Center

Girden, Ellen R.

This book in intended to train students in reading a research report critically. It uses actual research articles as examples including both good and flawed studies in each category and provides interpretation and evaluation of the appropriateness of the statistical analyses in each study. Individual chapters usually include two sample studies and…

Mathematics Education as a Science and a Profession

ERIC Educational Resources Information Center

Kolar-Begovic, Zdenka, Ed.; Kolar-Šuper, Ružica, Ed.; Jukic Matic, Ljerka, Ed.

2017-01-01

The papers in the monograph address different topics related to mathematics teaching and learning processes which are of great interest to both students and prospective teachers. Some papers open new research questions, some show examples of good practice and others provide more information about earlier findings. The monograph consists of six…

Making Child Care Better: State Initiatives.

ERIC Educational Resources Information Center

Groginsky, Scott; Robison, Susan; Smith, Shelley

In light of increasing evidence that good early childhood programs lead to school success, reduced delinquency and crime, and better job opportunities and productivity, state legislators are developing policies to improve these services. This report is designed to provide state lawmakers and their staff with research and state examples of policy…

Small City Transit : Chapel Hill, North Carolina : Public Transit Serving a University and Town

DOT National Transportation Integrated Search

1976-03-01

Chapel Hill, North Carolina, is an illustration of a public transit service providing a high level of service for a town its size and a good example of a cooperative arrangement between a town and a resident university. This case study is one of thir...

Using a Video Projector for Color-Mixing Demonstrations.

ERIC Educational Resources Information Center

Bartels, Richard A.

1982-01-01

Suggestions are provided for using color television projector systems to demonstrate color mixing. With such a projector, manipulation of the three primary colors can be done by simply covering and uncovering the three separate beams. In addition, projector systems serve as good examples in studying geometrical optics. (Author/JN)

Combining Vocational and Higher Education Studies to Provide Dual Parallel Qualifications

ERIC Educational Resources Information Center

McLaughlin, Patricia; Mills, Anthony

2011-01-01

Developing academic relationships between vocational colleges and universities in Australia has been problematic, with exchanges between the two sectors limited to linear articulation and prescribed credit transfer. Whilst some very good examples of collaboration exist, in general the two sectors operate independently of each other. The isolation…

Latino Parents and Students Foster Literacy through a Culturally Relevant Folk Medicine Event

ERIC Educational Resources Information Center

Huerta, Mary Esther Soto; Riojas-Cortez, Mari

2011-01-01

This study was inspired by the literary elements of "cuentos tipicos" (culturally-relevant stories). The book "Prietita y la llorona" ("Prietita and the Ghost Woman") written by Anzaldua (1995) is a good example of a "cuento" that provides information about medicinal herbs and also includes…

How to reduce your fire insurance rates

NASA Technical Reports Server (NTRS)

Dubain, M.

1971-01-01

Construction procedures and utilization of materials to reduce the cost of insuring large buildings against losses from fire are discussed. Examples of good and bad techniques in building construction and fire safety management are provided. The inadequacies of building codes and the hazards resulting from improper construction are examined.

Ecosystem goods and services from Swedish coastal habitats: identification, valuation, and implications of ecosystem shifts.

PubMed

Rönnbäck, Patrik; Kautsky, Nils; Pihl, Leif; Troell, Max; Söderqvist, Tore; Wennhage, Håkan

2007-11-01

Coastal areas are exposed to a variety of threats due to high population densities and rapid economic development. How will this affect human welfare and our dependence on nature's capacity to provide ecosystem goods and services? This paper is original in evaluating this concern for major habitats (macroalgae, seagrasses, blue mussel beds, and unvegetated soft bottoms) in a temperate coastal setting. More than 40 categories of goods and services are classified into provisional, regulating, and cultural services. A wide variety of Swedish examples is described for each category, including accounts of economic values and the relative importance of different habitats. For example, distinguishing characteristics would be the exceptional importance of blue mussels for mitigation of eutrophication, sandy soft bottoms for recreational uses, and seagrasses and macroalgae for fisheries production and control of wave and current energy. Net changes in the provision of goods and services are evaluated for three cases of observed coastal ecosystem shifts: i) seagrass beds into unvegetated substrate; ii) unvegetated shallow soft bottoms into filamentous algal mat dominance; and iii) macroalgae into mussel beds on hard substrate. The results are discussed in a management context including accounts of biodiversity, interconnectedness of ecosystems, and potential of economic valuation.

Centralized vs. Decentralized Child Mental Health Services

PubMed Central

Adams, Milton S.

1977-01-01

One of the basic tenets of the Community Mental Health Center movement is that services should be provided in the consumers' community. Various centers across the country have attempted to do this in either a centralized or decentralized fashion. Historically, most health services have been provided centrally, a good example being the traditional general hospital with its centralized medical services. Over the years, some of these services have become decentralized to take the form of local health centers, health maintenance organizations, community clinics, etc, and now various large mental health centers are also being broken down into smaller community units. An example of each type of mental health facility is delineated here. PMID:904014

Multiple Criteria Decision Analysis for Health Care Decision Making--Emerging Good Practices: Report 2 of the ISPOR MCDA Emerging Good Practices Task Force.

PubMed

Marsh, Kevin; IJzerman, Maarten; Thokala, Praveen; Baltussen, Rob; Boysen, Meindert; Kaló, Zoltán; Lönngren, Thomas; Mussen, Filip; Peacock, Stuart; Watkins, John; Devlin, Nancy

2016-01-01

Health care decisions are complex and involve confronting trade-offs between multiple, often conflicting objectives. Using structured, explicit approaches to decisions involving multiple criteria can improve the quality of decision making. A set of techniques, known under the collective heading, multiple criteria decision analysis (MCDA), are useful for this purpose. In 2014, ISPOR established an Emerging Good Practices Task Force. The task force's first report defined MCDA, provided examples of its use in health care, described the key steps, and provided an overview of the principal methods of MCDA. This second task force report provides emerging good-practice guidance on the implementation of MCDA to support health care decisions. The report includes: a checklist to support the design, implementation and review of an MCDA; guidance to support the implementation of the checklist; the order in which the steps should be implemented; illustrates how to incorporate budget constraints into an MCDA; provides an overview of the skills and resources, including available software, required to implement MCDA; and future research directions. Copyright © 2016 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

Five Skills Psychiatrists Should Have in Order to Provide Patients with Optimal Ethical Care

PubMed Central

2011-01-01

Analyses of empirical research and ethical problems require different skills and approaches. This article presents five core skills psychiatrists need to be able to address ethical problems optimally. These include their being able to recognize ethical conflicts and distinguish them from empirical questions, apply all morally relevant values, and know good from bad ethical arguments. Clinical examples of each are provided. PMID:21487542

Empowerment, Participation, and Democracy? -- The Hong Kong Big Sisters' Guidance Programme.

ERIC Educational Resources Information Center

Bottery, Mike; Siu, Shun-Mei

1996-01-01

Asserts that the Big Sisters Programme in Hong Kong provides a good example of a scheme that transcends personal and school issues and facilitates a more participative and democratic view of society. Characterizes the program as a benign form of a "hidden curriculum" and recommends establishing it in secondary schools. (MJP)

Learning from Experience--How Development Projects Spread "Good Practice" in Britain.

ERIC Educational Resources Information Center

Clynes, Roger

1992-01-01

Architects and Buildings Branch (A&B) of Department of Education in London, England, is specifically responsible for design and management of educational facilities. Current development project provides example of emphasis, aims, methods of work, and outcome of a typical project. Fact file on British public schools and list of type of reports…

When a High Distinction Isn't Good Enough: A Review of Perfectionism and Self-Handicapping

ERIC Educational Resources Information Center

Kearns, Hugh; Forbes, Angus; Gardiner, Maria; Marshall, Kelly

2008-01-01

This paper addresses two problems which are common amongst university students, namely perfectionism and self-handicapping. Perfectionism deals with setting unreasonably high standards for one's own performance, while self-handicapping behaviours provide a possible excuse for poor performance, for example putting tasks off until the last minute.…

39 CFR 265.13 - Compliance with subpoenas, summonses, and court orders by postal employees within the Inspection...

Code of Federal Regulations, 2010 CFR

2010-07-01

... assigned to the Postal Inspection Service, student interns, contractors and employees of contractors who... or testimony fails to cooperate in good faith, preventing Inspection Service legal counsel from... disruptive methods to the employee's official duties. Testimony may, for example, be provided by affidavits...

Combining Vocational and Higher Education Studies to Provide Dual Parallel Qualifications--An Australian Case Study

ERIC Educational Resources Information Center

McLaughlin, Patricia; Mills, Anthony

2011-01-01

Developing academic relationships between vocational colleges and universities in Australia has been problematic, with exchanges between the two sectors limited to linear articulation and prescribed credit transfer. Whilst some very good examples of collaboration exist, the two sectors generally operate independently of each other. The isolation…

From Dissemination to Discernment: The Commodification of Literacy Instruction and the Fostering of Good Teacher Consumerism

ERIC Educational Resources Information Center

Hibbert, Kathryn; Iannacci, Luigi

2005-01-01

In the current industry-driven educational climate, resources are produced, marketed, and subsequently understood to be synonymous with "balanced literacy." This article critically examines various programs currently in wide use to demonstrate this occurrence. The examination specifically provides examples of how the appropriation and…

Developmental Changes in the Consideration of Sample Diversity in Inductive Reasoning

ERIC Educational Resources Information Center

Rhodes, Marjorie; Gelman, Susan A.; Brickman, Daniel

2008-01-01

Determining whether a sample provides a good basis for broader generalizations is a basic challenge of inductive reasoning. Adults apply a diversity-based strategy to this challenge, expecting diverse samples to be a better basis for generalization than homogeneous samples. For example, adults expect that a property shared by two diverse mammals…

Global public goods for health: weaknesses and opportunities in the global health system.

PubMed

Moon, Suerie; Røttingen, John-Arne; Frenk, Julio

2017-04-01

Since at least the 1990s, there has been growing recognition that societies need global public goods (GPGs) in order to protect and promote public health. While the term GPG is sometimes used loosely to denote that which is 'good' for the global public, we restrict our use of the term to its technical definition (goods that are non-excludable and non-rival in consumption) for its useful analytical clarity. Examples of important GPGs for health include standards and guidelines, research on the causes and treatment of disease, and comparative evidence and analysis. While institutions for providing public goods are relatively well developed at the national level - being clearly recognized as a responsibility of sovereign states - institutional arrangements to do so remain fragmented and thin at the global level. For example, the World Health Organization, mandated to provide many GPGs, is not appropriately financed to do so. Three steps are needed to better govern the financing and provision of GPGs for health: first, improved data to develop a clearer picture of how much money is currently going to providing which types of GPGs; second, a legitimate global political process to decide upon priority missing GPGs, followed by estimates of total amounts needed; and third, financing streams for GPGs from governments and private sources, to be channeled through new or existing institutions. Financing should go toward fully financing some GPGs, complementing or supplementing existing national or international financing for others, or deploying funds to make potential GPGs less 'excludable' by putting them into the public domain. As globalization deepens the degree of interdependence between countries and as formerly low-income economies advance, there may be less relative need for development assistance to meet basic health care needs, and greater relative need to finance GPGs. Strengthening global arrangements for GPGs today is a worthy investment for improved global health in the years to come.

Technical Excellence: A Requirement for Good Engineering

NASA Technical Reports Server (NTRS)

Gill, Paul S.; Vaughan, William W.

2008-01-01

Technical excellence is a requirement for good engineering. Technical excellence has many different ways of expressing itself within engineering. NASA has initiatives that address the enhancement of the Agency's technical excellence and thrust to maintain the associated high level of performance by the Agency on current programs/projects and as it moves into the Constellation Program and the return to the Moon with plans to visit Mars. This paper addresses some of the key initiatives associated with NASA's technical excellence thrust. Examples are provided to illustrate some results being achieved and plans to enhance these initiatives.

Narrative Practice and the Signs of Safety Approach: Engaging Adolescents in Building Rigorous Safety Plans

ERIC Educational Resources Information Center

Gibson, Matthew

2014-01-01

The Signs of Safety approach to child protection has been gaining prominence around the world and this approach has developed through learning from good practice. Generally, examples of good practice are derived from adults who pose a risk to children, while this paper outlines an example of good practice that engages an adolescent in building a…

Promoting Good Psychiatric Management for Patients With Borderline Personality Disorder.

PubMed

Links, Paul S; Ross, James; Gunderson, John G

2015-08-01

General psychiatric management for patients with borderline personality disorder was devised to be an outpatient intervention that could be readily learned and easily delivered by independent community mental health professionals. To disseminate the approach, Drs. Gunderson and Links developed the Handbook of Good Psychiatric Management for Borderline Personality Disorder (Gunderson & Links, ) that presented the basics of the approach, videos to illustrate the appropriate clinical skills, and case examples to practice adherence to the approach. Unfortunately, the inclusion of "psychiatric" in the treatment's name may discourage psychologists and other mental health professionals from using this therapy. In this article, we review the basic principles and approaches related to general psychiatric management. With a case example, we illustrate how psychologists can use all the general psychiatric management principles for their patients with BPD, except medications and, as a result, provide and deliver this approach effectively. © 2015 Wiley Periodicals, Inc.

Tested Tools You Can Use: Evaluating Earth System Science Courses

NASA Astrophysics Data System (ADS)

Lee, S. P.; Prakash, A.; Reider, D.; Baker, D.

2006-12-01

Earth System Science Education for the 21st Century (ESSE 21) has created a public access on-line evaluation resource available at http://esse21.usra.edu/evaltoolkit in collaboration with the ESSE 21 institutions, PIs, and evaluators. The purpose of the ESSE toolkit is to offer examples of how evaluation and assessment are/have been used in Earth System Science courses and programs. Our goal is to help instructors recognize different types of assessment and evaluation tools and uses that have proved useful in these courses and provide models for designing assessments in new courses. We have included actual examples of evaluations used by ESSE institution faculty in their own courses. This is not a comprehensive toolkit on educational evaluation and assessment, but it does provide several examples of evaluations that have been used successfully in Earth System Science courses and links to many good web resources on course evaluation. We have provided examples of assessments that are designed to collect information from students before, during and after courses. Some, presented in different formats, are designed to assess what students learn, others are designed to provide course instructors with information they can use to revise their courses. These assessments range from content tests to portfolios, from feedback forms to interviews, and from concept maps to attitude surveys.

What Does Good Education Research Look Like? Conducting Educational Research

ERIC Educational Resources Information Center

Yates, Lyn

2004-01-01

This book explains the debates that bedevil education research--for example that it is low quality, or not scientific enough, or not useful enough--and shows how research in education must meet different demands in different places, times and conditions. A major part of the book provides detailed analyses and guidance to different areas in which…

Leading across Boundaries: Collaborative Leadership and the Institutional Repository in Research Universities and Liberal Arts Colleges

ERIC Educational Resources Information Center

Seaman, David M.

2017-01-01

Libraries often engage in services that require collaboration across stakeholder boundaries to be successful. Institutional repositories (IRs) are a good example of such a service. IRs are an infrastructure to preserve intellectual assets within a university or college, and to provide an open access showcase for that institution's research,…

(If Social Studies Is Wrong) I Don't Want to Be Right

ERIC Educational Resources Information Center

Ross, E. Wayne; Marker, Perry M.

2005-01-01

There are at least two good reasons to pay serious attention to the latest skirmish in the social studies wars. First, it is one of the most prominent examples of "movement conservatism" to involve established social studies researchers; and secondly, it provides an opportunity for social educators to scrutinize the fundamental dilemma embedded in…

Guided Viewing of Film with Gifted Students: Resources for Educators and Counselors

ERIC Educational Resources Information Center

Hebert, Thomas P.; Hammond, Daniel R.

2006-01-01

Using movies to guide gifted students toward self-understanding provides them with numerous benefits. Movies have the potential to enrich and influence the lives of gifted students in constructive ways. A good movie, for example, can become a meaningful metaphor that explains the essence of a young person's dilemma. When an appropriate movie is…

An Overview of the Scholarship of Teaching and Learning in Mathematics

ERIC Educational Resources Information Center

Bennett, Curtis D.; Dewar, Jacqueline M.

2012-01-01

This article provides an overview of the scholarship of teaching and learning (SoTL) in mathematics. It describes the origins of SoTL in higher education and distinguishes SoTL from good teaching, scholarly teaching, and mathematics education research. It includes a widely adopted taxonomy of SoTL questions and presents several examples of SoTL…

7 CFR 46.44 - Good delivery.

Code of Federal Regulations, 2010 CFR

2010-01-01

...) Lettuce. (1) If the contract specifies a U.S. grade, the lettuce may contain an average of not more than 3... U.S. Standards for Grades of Lettuce. (For example, the U.S. No. 1 grade provides a 12 percent... lettuce at destination may contain a maximum of 15 percent, by count, of the heads in any lot which are...

Speaking like a "Good American": National Identity and the Legacy of German-Language Education

ERIC Educational Resources Information Center

Kibler, Amanda

2008-01-01

Background/Context: As a case study in minority language restriction, the German example provides a useful historical counterpoint to more recent debates regarding the place of non-English languages in American schools. Purpose/Objective/Research Question/Focus of Study and Research Design: This historical analysis examines the role of education…

An Example for Portfolio Preparation in German Teacher Training

ERIC Educational Resources Information Center

Arak, Hüseyin

2017-01-01

In this study we are trying with the help of portfolio in teacher training and the diagnosis of the learning group concerning their skills in translation from German to Turkish, to show the documentation of the learning process. The portfolio provides a good overview about the performance of the students and it also prepares a basis for…

Good IR duals of bad quiver theories

NASA Astrophysics Data System (ADS)

Dey, Anindya; Koroteev, Peter

2018-05-01

The infrared dynamics of generic 3d N = 4 bad theories (as per the good-bad-ugly classification of Gaiotto and Witten) are poorly understood. Examples of such theories with a single unitary gauge group and fundamental flavors have been studied recently, and the low energy effective theory around some special point in the Coulomb branch was shown to have a description in terms of a good theory and a certain number of free hypermultiplets. A classification of possible infrared fixed points for bad theories by Bashkirov, based on unitarity constraints and superconformal symmetry, suggest a much richer set of possibilities for the IR behavior, although explicit examples were not known. In this note, we present a specific example of a bad quiver gauge theory which admits a good IR description on a sublocus of its Coulomb branch. The good description, in question, consists of two decoupled quiver gauge theories with no free hypermultiplets.

Focusing on customer service.

PubMed

1996-01-01

This booklet is devoted to a consideration of how good customer service in family planning programs can generate demand for products and services, bring customers back, and reduce costs. Customer service is defined as increasing client satisfaction through continuous concern for client preferences, staff accountability to clients, and respect for the rights of clients. Issues discussed include the introduction of a customer service approach and gaining staff commitment. The experience of PROSALUD in Bolivia in recruiting appropriate staff, supervising staff, soliciting client feedback, and marketing services is offered as an example of a successful customer service approach. The key customer service functions are described as 1) establishing a welcoming atmosphere, 2) streamlining client flow, 3) personalizing client services, and 4) organizing and providing clear information to clients. The role of the manager in developing procedures is explored, and the COPE (Client-Oriented Provider-Efficient) process is presented as a good way to begin to make improvements. Techniques in staff training in customer service include brainstorming, role playing, using case studies (examples of which are provided), and engaging in practice sessions. Training also leads to the development of effective customer service attitudes, and the differences between these and organizational/staff-focused attitudes are illustrated in a chart. The use of communication skills (asking open-ended questions, helping clients express their concerns, engaging in active listening, and handling difficult situations) is considered. Good recovery skills are important when things go wrong. Gathering and using client feedback is the next topic considered. This involves identifying, recording, and discussing customer service issues as well as taking action on these issues and evaluating the results. The booklet ends by providing a sample of customer service indicators, considering the maintenance of a customer service focus, and reporting comments from the reviewers of the booklet.

Generic Example Proving Criteria for All

ERIC Educational Resources Information Center

Yopp, David; Ely, Rob; Johnson­-Leung, Jennifer

2015-01-01

We review literature that discusses generic example proving and highlight ambiguities that pervade our research community's discourse about generic example arguments. We distinguish between pedagogical advice for choosing good examples that can serve as generic examples when teaching and advice for developing generic example arguments. We provide…

Homogeneite et heterogeneite de la langue latine selon Varron et Aulu-Gelle: aspects historique, social et fonctionnel (Homogeneity and Heterogeneity in the Latin Language According to Varron and Aulu-Gelle: Historic, Social and Functional Aspects).

ERIC Educational Resources Information Center

Amacker, Rene

2001-01-01

Of the many Latin texts that provide views on language, and in particular on linguistic change and variation, Varro's "De Lingua Latina" and Gellius'"Noctes Atticae," provide good examples of the perspectives of the stoic philosopher and of the antiquarian philologist. Stoics suggest that language was created as perfect as…

Legally Sustainable Solutions for Privacy Issues in Collaborative Fraud Detection

NASA Astrophysics Data System (ADS)

Flegel, Ulrich; Kerschbaum, Florian; Miseldine, Philip; Monakova, Ganna; Wacker, Richard; Leymann, Frank

One company by itself cannot detect all instances of fraud or insider attacks. An example is the simple case of buyer fraud: a fraudulent buyer colludes with a supplier creating fake orders for supplies that are never delivered. They circumvent internal controls in place to prevent this kind of fraud, such as a goods receipt, e.g., by ordering services instead of goods. Based on the evidence collected at one company, it is often extremely difficult to detect such fraud, but if companies collaborate and correlate their evidence, they could detect that the ordered services have never actually been provided.

Can one do good medical ethics without principles?

PubMed

Macklin, Ruth

2015-01-01

The criteria for determining what it is to do good medical ethics are the quality of ethical analysis and ethical justifications for decisions and actions. Justifications for decisions and actions rely on ethical principles, be they the 'famous four' or subsidiary ethical principles relevant to specific contexts. Examples from clinical ethics, research ethics and public health ethics reveal that even when not stated explicitly, principles are involved in ethical justifications. Principles may come into conflict, however, and the resolution of an ethical dilemma requires providing good reasons for preferring one principle over another. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

The Ideal Man and Woman According to University Students

ERIC Educational Resources Information Center

Weinstein, Lawrence; Laverghetta, Antonio V.; Peterson, Scott A.

2009-01-01

The present study determined if the ideal man has changed over the years and who and what the ideal woman is. We asked students at Cameron University to rate the importance of character traits that define the ideal man and woman. Subjects also provided examples of famous people exemplifying the ideal, good, average, and inferior man and woman. We…

Coastal forests and groundwater: Using case studies to understand the effects of drivers and stressors for resource management

Treesearch

Timothy Callahan; Devendra Amatya; Peter Stone

2017-01-01

Forests are receiving more attention for the ecosystem goods and services they provide and the potential change agents that may affect forest health and productivity. Highlighting case examples from coastal forests in South Carolina, USA, we describe groundwater processes with respect to stressors and potential responses of a wetland-rich forested landscape,...

Model Policies in Support of High Performance School Buildings for All Children

ERIC Educational Resources Information Center

21st Century School Fund, 2006

2006-01-01

Model Policies in Support of High Performance School Buildings for All Children is to begin to create a coherent and comprehensive set of state policies that will provide the governmental infrastructure for effective and creative practice in facility management. There are examples of good policy in many states, but no state has a coherent set of…

28 CFR Appendix B to Part 36 - Preamble to Regulation on Nondiscrimination on the Basis of Disability by Public Accommodations...

Code of Federal Regulations, 2010 CFR

2010-07-01

... that limited his or her enjoyment of the goods or services being offered. For example, persons with.... It also applies, in accordance with section 309 of the ADA, to private entities that offer... relay services. Title IV of the Act provides adequate protections for ensuring the confidentiality of...

A Service Value Model for Continued Use of Online Services: Conceptual Development and Empirical Examination

ERIC Educational Resources Information Center

Hu, Tao

2009-01-01

Online services (OLS) provide billions of Internet users with a variety of opportunities to exchange goods, share information, and develop or maintain relationships. Popular examples of OLS web sites include eBay.com, Amazon.com, Dell.com, Craigslist.com, MSN.com, Yahoo.com, LinkedIn.com, Zillow.com, Facebook.com, Wikipedia.com, and Twitter.com.…

Financial reporting.

PubMed

Bachrach, D J; Farrell, N L

1985-01-01

"How are we doing?" Financial reports must provide the answer to this all-important question for every medical group. Although there are some key differences between academic practices and private group practices, good financial reports and statements of activity are essential in all situations. Examples are provided here of how financial information can be communicated to the several organizational levels that need the information, as well as how financial planning, measurement, and control are part of this communication process. Sample formats outline the important ingredients for making your group's reports more useful.

Efficient Computing Budget Allocation for Finding Simplest Good Designs

PubMed Central

Jia, Qing-Shan; Zhou, Enlu; Chen, Chun-Hung

2012-01-01

In many applications some designs are easier to implement, require less training data and shorter training time, and consume less storage than the others. Such designs are called simple designs, and are usually preferred over complex ones when they all have good performance. Despite the abundant existing studies on how to find good designs in simulation-based optimization (SBO), there exist few studies on finding simplest good designs. We consider this important problem in this paper, and make the following contributions. First, we provide lower bounds for the probabilities of correctly selecting the m simplest designs with top performance, and selecting the best m such simplest good designs, respectively. Second, we develop two efficient computing budget allocation methods to find m simplest good designs and to find the best m such designs, respectively; and show their asymptotic optimalities. Third, we compare the performance of the two methods with equal allocations over 6 academic examples and a smoke detection problem in wireless sensor networks. We hope that this work brings insight to finding the simplest good designs in general. PMID:23687404

Factors supporting good partnership working between generalist and specialist palliative care services: a systematic review.

PubMed

Gardiner, Clare; Gott, Merryn; Ingleton, Christine

2012-05-01

The care that most people receive at the end of their lives is provided not by specialist palliative care professionals but by generalists such as GPs, district nurses and others who have not undertaken specialist training in palliative care. A key focus of recent UK policy is improving partnership working across the spectrum of palliative care provision. However there is little evidence to suggest factors which support collaborative working between specialist and generalist palliative care providers. To explore factors that support partnership working between specialist and generalist palliative care providers. Systematic review. A systematic review of studies relating to partnership working between specialist and generalist palliative care providers was undertaken. Six electronic databases were searched for papers published up until January 2011. Of the 159 articles initially identified, 22 papers met the criteria for inclusion. Factors supporting good partnership working included: good communication between providers; clear definition of roles and responsibilities; opportunities for shared learning and education; appropriate and timely access to specialist palliative care services; and coordinated care. Multiple examples exist of good partnership working between specialist and generalist providers; however, there is little consistency regarding how models of collaborative working are developed, and which models are most effective. Little is known about the direct impact of collaborative working on patient outcomes. Further research is required to gain the direct perspectives of health professionals and patients regarding collaborative working in palliative care, and to develop appropriate and cost-effective models for partnership working.

Materials derived from biomass/biodegradable materials.

PubMed Central

Luzier, W D

1992-01-01

Interest in biodegradable plastics made from renewable resources has increased significantly in recent years. PHBV (polyhydroxybutyrate-polyhydroxyvalerate) copolymers are good examples of this type of materials. This paper provides an overview of the manufacturing process, properties, biodegradability, and application/commercial issues associated with PHBV copolymers. They are naturally produced by bacteria from agricultural raw materials, and they can be processed to make a variety of useful products, where their biodegradability and naturalness are quite beneficial. PHBV copolymers are still in the first stage of commercialization. But they are presented in this paper as an example of how new technology can help meet society's needs for plastics and a clean environment. Images PMID:1736301

Psychiatry during the Nazi era: ethical lessons for the modern professional

PubMed Central

Strous, Rael D

2007-01-01

For the first time in history, psychiatrists during the Nazi era sought to systematically exterminate their patients. However, little has been published from this dark period analyzing what may be learned for clinical and research psychiatry. At each stage in the murderous process lay a series of unethical and heinous practices, with many psychiatrists demonstrating a profound commitment to the atrocities, playing central, pivotal roles critical to the success of Nazi policy. Several misconceptions led to this misconduct, including allowing philosophical constructs to define clinical practice, focusing exclusively on preventative medicine, allowing political pressures to influence practice, blurring the roles of clinicians and researchers, and falsely believing that good science and good ethics always co-exist. Psychiatry during this period provides a most horrifying example of how science may be perverted by external forces. It thus becomes crucial to include the Nazi era psychiatry experience in ethics training as an example of proper practice gone awry. PMID:17326822

A knowledge infrastructure for occupational safety and health.

PubMed

van Dijk, Frank J H; Verbeek, Jos H; Hoving, Jan L; Hulshof, Carel T J

2010-12-01

Occupational Safety and Health (OSH) professionals should use scientific evidence to support their decisions in policy and practice. Although examples from practice show that progress has been made in evidence-based decision making, there is a challenge to improve and extend the facilities that support knowledge translation in practice. A knowledge infrastructure that supports OSH practice should include scientific research, systematic reviews, practice guidelines, and other tools for professionals such as well accessible virtual libraries and databases providing knowledge, quality tools, and good learning materials. A good infrastructure connects facilities with each other and with practice. Training and education is needed for OSH professionals in the use of evidence to improve effectiveness and efficiency. New initiatives show that occupational health can profit from intensified international collaboration to establish a good functioning knowledge infrastructure.

Teaching hearing science to undergraduate nonscientists

NASA Astrophysics Data System (ADS)

Weiler, Ernest M.; Boyce, Suzanne; Steger, Joseph

2003-04-01

For those students interested in potential clinical careers in Speech Pathology, or Audiology, a knowledge of some of the scientific bases is important, but should not create a distaste for science. The authors have addressed themselves to these goals: (1) calculation of period, Hz, summation of two sine waves, phase and dB; (2) anticipating undergraduate Speech Science; (3) simple examples of hearing pathology; and (4) basic psycho-acoustical issues. The classic material of Harry Helson was used to elucidate issues of context in experimental science, and that of S.S. Stevens was used to exemplify psycho-acoustical formulas of common use. Four texts that have been tried on approximately 200 students were evaluated. Surprisingly, the best provided the fewest formulas, short study questions with answers, good examples, and a list of common terms. The next best was aimed at slightly more advanced students, but each chapter contained introductory material, examples, and definitions suitable for naïve undergraduates. The least satisfactory text provided excerpts of technical material with abrupt transitions, no examples, and only part of the definitions needed for the naïve student. Perhaps the most difficult teaching issue is to avoid demanding graduate-level science from those undergraduates with clinical aspirations.

Non-holonomic integrators

NASA Astrophysics Data System (ADS)

Cortés, J.; Martínez, S.

2001-09-01

We introduce a discretization of the Lagrange-d'Alembert principle for Lagrangian systems with non-holonomic constraints, which allows us to construct numerical integrators that approximate the continuous flow. We study the geometric invariance properties of the discrete flow which provide an explanation for the good performance of the proposed method. This is tested on two examples: a non-holonomic particle with a quadratic potential and a mobile robot with fixed orientation.

The Tribology of Undulated Surfaces

DTIC Science & Technology

1989-05-30

wear, in effect by decreasing the impact of plowing. Lubrication, hard coatings, fiber-reinforced composites are but a few examples. All these methods ha...In addition, the effects of pad width and cavity volume fraction of the undulated surface were also investigated. A plowing model proposed for...boundary lubricated sliding is in good agreement with experimental results. It is suggested, furthermore, that the undulated surfaces provide an effective

Information, Advocacy and Signposting as a Low-Level Support for Adults with High-Functioning Autism Spectrum Disorder: An Example from the UK

ERIC Educational Resources Information Center

Southby, Kris; Robinson, Olivia

2018-01-01

"Low-level" support is championed to support adults with high functioning autism spectrum disorder (HFASD) to achieve good quality health and social care, yet research in the area is sparse. Drawing on semi-structured interview data, this paper considers the efficacy of an intervention to provide low-level support to adults with HFASD…

Method of improving system performance and survivability through changing function

NASA Technical Reports Server (NTRS)

Hinchey, Michael G. (Inventor); Vassev, Emil I. (Inventor)

2012-01-01

A biologically-inspired system and method is provided for self-adapting behavior of swarm-based exploration missions, whereby individual components, for example, spacecraft, in the system can sacrifice themselves for the greater good of the entire system. The swarm-based system can exhibit emergent self-adapting behavior. Each component can be configured to exhibit self-sacrifice behavior based on Autonomic System Specification Language (ASSL).

Interpretation and Use of K-12 Language Proficiency Assessment Score Reports: Perspectives of Educators and Parents. WCER Working Paper No. 2016-8

ERIC Educational Resources Information Center

Kim, Ahyoung Alicia; Kondo, Akira; Blair, Alissa; Mancilla, Lorena; Chapman, Mark; Wilmes, Carsten

2016-01-01

A number of English language proficiency exams target grades K-12 English language learners (ELLs) because of the rising need to identify their needs and provide appropriate support in language learning. A good example is the WIDA ACCESS for ELLs (hereafter ACCESS), designed to measure the English language proficiency of students identified as…

Bounds on Block Error Probability for Multilevel Concatenated Codes

NASA Technical Reports Server (NTRS)

Lin, Shu; Moorthy, Hari T.; Stojanovic, Diana

1996-01-01

Maximum likelihood decoding of long block codes is not feasable due to large complexity. Some classes of codes are shown to be decomposable into multilevel concatenated codes (MLCC). For these codes, multistage decoding provides good trade-off between performance and complexity. In this paper, we derive an upper bound on the probability of block error for MLCC. We use this bound to evaluate difference in performance for different decompositions of some codes. Examples given show that a significant reduction in complexity can be achieved when increasing number of stages of decoding. Resulting performance degradation varies for different decompositions. A guideline is given for finding good m-level decompositions.

Click Chemistry in Complex Mixtures: Bioorthogonal Bioconjugation

PubMed Central

McKay, Craig S.; Finn, M.G.

2014-01-01

The selective chemical modification of biological molecules drives a good portion of modern drug development and fundamental biological research. While a few early examples of reactions that engage amine and thiol groups on proteins helped establish the value of such processes, the development of reactions that avoid most biological molecules so as to achieve selectivity in desired bond-forming events has revolutionized the field. We provide an update on recent developments in bioorthogonal chemistry that highlights key advances in reaction rates, biocompatibility, and applications. While not exhaustive, we hope this summary allows the reader to appreciate the rich continuing development of good chemistry that operates in the biological setting. PMID:25237856

Design and Implementation of KSP on the Next Generation Cryptography API

NASA Astrophysics Data System (ADS)

Lina, Zhang

With good seamless connectivity and higher safety, KSP (Key Storage Providers) is the inexorable trend of security requirements and development to take the place of CSP (Cryptographic Service Provider). But the study on KSP has just started in our country, and almost no reports of its implementation can be found. Based on the analysis of function modules and the architecture of Cryptography API (Next Generation (CNG)), this paper discusses the design and implementation of KSP (key storage providers) based on smart card in detail, and an example is also presented to illustrate how to use KSP in Windows Vista.

Simple Perturbation Example for Quantum Chemistry.

ERIC Educational Resources Information Center

Goodfriend, P. L.

1985-01-01

Presents a simple example that illustrates various aspects of the Rayleigh-Schrodinger perturbation theory. The example is a particularly good one because it is straightforward and can be compared with both the exact solution and with experimental data. (JN)

Publishing Outside the Box: Popular Press Books.

PubMed

Vyse, Stuart

2014-10-01

Writing and publishing popular press books requires a set of skills, not natural to basic and applied researchers trained to publish in peer-referred behavior analytic journals or to practice behavior analysis in applied settings. This article provides suggestions and examples. These include finding a distinctive idea, securing a contract, hiring an agent (or not), deciding on a publisher, and writing engagingly for a broad audience. The last is the greatest challenge. Among my recommendations are to read good prose, good models, and good books about publishing; talk to experienced colleagues; read aloud to judge the appropriateness of your vocabulary and style; and interject humor, imagery, and drama. Book publishing is a long and difficult process, but it is possible. It has a great potential for bringing behavior analytic research, practice and theory to the attention of the general public.

Empowering Globally Integrated Operations and Mission Command: Revisiting Key West

DTIC Science & Technology

2013-03-01

depended on coordination between commanders. Examples include Captain Thomas McDonough’s 4 U.S...Hedgehog Concept In his book, Good to Great, which describes how good organizations become great ones, Jim Collins borrows an example from an Isaiah ...that it executes with perfection—curling into a ball with its spikes outward. 62 In the words of Archilochus (first line in quotes), Isaiah Berlin

A practical introduction to tensor networks: Matrix product states and projected entangled pair states

DOE Office of Scientific and Technical Information (OSTI.GOV)

Orús, Román, E-mail: roman.orus@uni-mainz.de

This is a partly non-technical introduction to selected topics on tensor network methods, based on several lectures and introductory seminars given on the subject. It should be a good place for newcomers to get familiarized with some of the key ideas in the field, specially regarding the numerics. After a very general introduction we motivate the concept of tensor network and provide several examples. We then move on to explain some basics about Matrix Product States (MPS) and Projected Entangled Pair States (PEPS). Selected details on some of the associated numerical methods for 1d and 2d quantum lattice systems aremore » also discussed. - Highlights: • A practical introduction to selected aspects of tensor network methods is presented. • We provide analytical examples of MPS and 2d PEPS. • We provide basic aspects on several numerical methods for MPS and 2d PEPS. • We discuss a number of applications of tensor network methods from a broad perspective.« less

A feasible strategy to balance the crystallinity and specific surface area of metal oxide nanocrystals

NASA Astrophysics Data System (ADS)

Zhang, Q. P.; Xu, X. N.; Liu, Y. T.; Xu, M.; Deng, S. H.; Chen, Y.; Yuan, H.; Yu, F.; Huang, Y.; Zhao, K.; Xu, S.; Xiong, G.

2017-04-01

Practical, efficient synthesis of metal oxide nanocrystals with good crystallinity and high specific surface area by a modified polymer-network gel method is demonstrated, taking ZnO nanocrystals as an example. A novel stepwise heat treatment yields significant improvement in crystal quality. Such nanophase materials can effectively degrade common organic dyes under solar radiation and can perform very well in photo-assisted detection of NO2 gas. Other typical metal oxide nanocrystals with good crystallinity and high specific surface area were also synthesized successfully under similar conditions. This work provides a general strategy for the synthesis of metal oxide nanocrystals, balancing the crystallinity and specific surface area.

Seeing is believing: good graphic design principles for medical research.

PubMed

Duke, Susan P; Bancken, Fabrice; Crowe, Brenda; Soukup, Mat; Botsis, Taxiarchis; Forshee, Richard

2015-09-30

Have you noticed when you browse a book, journal, study report, or product label how your eye is drawn to figures more than to words and tables? Statistical graphs are powerful ways to transparently and succinctly communicate the key points of medical research. Furthermore, the graphic design itself adds to the clarity of the messages in the data. The goal of this paper is to provide a mechanism for selecting the appropriate graph to thoughtfully construct quality deliverables using good graphic design principles. Examples are motivated by the efforts of a Safety Graphics Working Group that consisted of scientists from the pharmaceutical industry, Food and Drug Administration, and academic institutions. Copyright © 2015 John Wiley & Sons, Ltd.

Breaking barriers to care: a community of solution for chronic disease management.

PubMed

Sanders, Jim; Solberg, Bill; Gauger, Michael

2013-01-01

For 10 years the Medical College of Wisconsin and Columbia St. Mary's Hospital have joined together in a partnership to work within some of Milwaukee's most impoverished neighborhoods. Beginning simply by providing health care through a free clinic, the partnership soon was confronted with numerous examples of barriers to care being experienced by patients. A community-based participatory action process allowed the local population to give voice to the local realities of barriers to care. Here we combine our anecdotal clinical experience, the neighborhood's input, and an example of a successful program from a low-resource international setting to create a novel approach to treating chronic disease in uninsured populations. This model of care has been successful for 2 reasons. First, the model shows good health outcomes at low cost. Second, solid community partnerships with care providers, churches, and other groups have been formed in support of the model, ensuring its credibility and sustainability.

Porous ceramics mimicking nature—preparation and properties of microstructures with unidirectionally oriented pores

PubMed Central

Okada, Kiyoshi; Isobe, Toshihiro; Katsumata, Ken-ichi; Kameshima, Yoshikazu; Nakajima, Akira; MacKenzie, Kenneth J D

2011-01-01

Porous ceramics with unidirectionally oriented pores have been prepared by various methods such as anodic oxidation, templating using wood, unidirectional solidification, extrusion, etc. The templating method directly replicates the porous microstructure of wood to prepare porous ceramics, whereas the extrusion method mimics the microstructures of tracheids and xylems in trees. These two methods are therefore the main focus of this review as they provide good examples of the preparation of functional porous ceramics with properties replicating nature. The well-oriented cylindrical through-hole pores prepared by the extrusion method using fibers as the pore formers provide excellent permeability together with high mechanical strength. Examples of applications of these porous ceramics are given, including their excellent capillary lift of over 1 m height which could be used to counteract urban heat island phenomena, and other interesting properties arising from anisotropic unidirectional porous structures. PMID:27877451

Summary statistics in auditory perception.

PubMed

McDermott, Josh H; Schemitsch, Michael; Simoncelli, Eero P

2013-04-01

Sensory signals are transduced at high resolution, but their structure must be stored in a more compact format. Here we provide evidence that the auditory system summarizes the temporal details of sounds using time-averaged statistics. We measured discrimination of 'sound textures' that were characterized by particular statistical properties, as normally result from the superposition of many acoustic features in auditory scenes. When listeners discriminated examples of different textures, performance improved with excerpt duration. In contrast, when listeners discriminated different examples of the same texture, performance declined with duration, a paradoxical result given that the information available for discrimination grows with duration. These results indicate that once these sounds are of moderate length, the brain's representation is limited to time-averaged statistics, which, for different examples of the same texture, converge to the same values with increasing duration. Such statistical representations produce good categorical discrimination, but limit the ability to discern temporal detail.

Future of DAQ Frameworks and Approaches, and Their Evolution towards the Internet of Things

NASA Astrophysics Data System (ADS)

Neufeld, Niko

2015-12-01

Nowadays, a DAQ system is a complex network of processors, sensors and many other active devices. Historically, providing a framework for DAQ has been a very important role of host institutes of experiments. Reviewing evolution of such DAQ frameworks is a very interesting subject of the conference. “Internet of Things” is a recent buzz word but a DAQ framework could be a good example of IoT.

JView Visualization for Next Generation Air Transportation System

DTIC Science & Technology

2011-01-01

hardware graphics acceleration. JView relies on concrete Object Oriented Design (OOD) and programming techniques to provide a robust and venue non...visibility priority of a texture set. A good example of this is you have translucent images that should always be visible over the other textures...elements present in the scene. • Capture Alpha. Allows the alpha color channel ( translucency ) to be saved when capturing images or movies of a 3D scene

Power Provision Based on Self-Sacrificing Craft

NASA Technical Reports Server (NTRS)

Hinchey, Michael G. (Inventor); Sterrit, Roy (Inventor); Vassev, Emil I. (Inventor); Hinchey, Bridget (Inventor)

2015-01-01

A biologically-inspired system and method is provided for self-adapting behavior of swarm-based exploration missions, whereby individual components, for example, spacecraft, in the system can sacrifice themselves for the greater good of the entire system. The self-sacrifice can involve donating resources or assets, such as power provisions, to a different component of an autonomous system. A receiving component of the system can benefit from receiving the donated resource or power provision.

Evaluating the Impact of Offshoring on US National Security

DTIC Science & Technology

2011-05-15

7, 2008. 53 Ibid. 54 Ibid. 55 N. Gregory Mankiw , “The Politics and Economics of Offshore Outsourcing,” Harvard University, November 9, 2009, 42...foreign countries to provide goods or services may appear to some as an example of national weakness. The weakness may consist of fragile economic ...weakness. The weakness may consist of fragile economic dependencies or exportation of critical skills. In both cases, the risk of losing relative

Motivation in Adult Language Learning: Research Review and Navy Applications

DTIC Science & Technology

2011-12-01

procedural aspects of some motivation studies giving rise to the cementing of the integrative/instrumental pair. For example, population samples in...subsequently, this led to a cementing of the integrative/instrumental pair in scholarly thought and a narrowing of scholarly perspectives on motivation.15...a desire to learn a second language or already have fluency or a working knowledge of one. All of these recommendations will provide a good start

Dumbing Down the Net

NASA Astrophysics Data System (ADS)

Jamison, Mark A.; Hauge, Janice A.

It is commonplace for sellers of goods and services to enhance the value of their products by paying extra for premium delivery service. For example, package delivery services such as Federal Express and the US Postal Service offer shippers a variety of delivery speeds and insurance programs. Web content providers such as Yahoo! and MSN Live Earth can purchase web-enhancing services from companies such as Akamai to speed the delivery of their web content to customers.1

Corps of Engineers Operations and Maintenance Budget Decision Support System (COMB-DSS): System Concept, Design and Prototype Evaluation. Volume 2. Appendixes B Through G.

DTIC Science & Technology

1994-04-01

Rather, it should provide, whenever possible, information on the location and/or quantity of work. Examples of good descriptions are as follows: Major...03100 D1UMNG IrMMlC CHAJE DOI TABI3s IMASON 1 -eascode 1323035 2 reason T231 64 code lookup table giving text for each integer reascode re*acode reaon 0

From evidence to action

PubMed Central

Verheyen, Cees CPM; Kerkhoffs, Gino M; Bhandari, Mohit; Schünemann, Holger J

2009-01-01

ABSTRACT Good guidelines will help us to take evidence into practice. In a survey among Dutch orthopedic surgeons, development and use of evidence-based guidelines was perceived as one of the best ways of moving from opinion-based to evidence-based orthopedic practice. The increasing number of guidelines means that knowing how to make a critical appraisal of guidelines is now a key part of every surgeon’s life. This is particularly true because guidelines use varying systems to judge the quality of evidence and the strength of recommendations. In this manuscript we discuss what a guideline is, where we can find guidelines, how to evaluate the quality of guidelines, and finally provide an example on the different steps of guideline development. Thus, we show that good guidelines are a summary of the best available evidence and that they provide a graded recommendation to help surgeons in evidence-based practice. PMID:19234892

Analysis of Logistics in Support of a Human Lunar Outpost

NASA Technical Reports Server (NTRS)

Cirillo, William; Earle, Kevin; Goodliff, Kandyce; Reeves, j. D.; Andrashko, Mark; Merrill, R. Gabe; Stromgren, Chel

2008-01-01

Strategic level analysis of the integrated behavior of lunar transportation system and lunar surface system architecture options is performed to inform NASA Constellation Program senior management on the benefit, viability, affordability, and robustness of system design choices. This paper presents an overview of the approach used to perform the campaign (strategic) analysis, with an emphasis on the logistics modeling and the impacts of logistics resupply on campaign behavior. An overview of deterministic and probabilistic analysis approaches is provided, with a discussion of the importance of each approach to understanding the integrated system behavior. The logistics required to support lunar surface habitation are analyzed from both 'macro-logistics' and 'micro-logistics' perspectives, where macro-logistics focuses on the delivery of goods to a destination and micro-logistics focuses on local handling of re-supply goods at a destination. An example campaign is provided to tie the theories of campaign analysis to results generation capabilities.

Payment for Environmental Services: Hypotheses and Evidence

PubMed Central

Alston, Lee J.; Andersson, Krister; Smith, Steven M.

2014-01-01

The use of payment for environmental services (PES) is not a new type of contract, but PES programs have become more in vogue because of the potential for sequestering carbon by paying to prevent deforestation and degradation of forestlands. We provide a framework utilizing transaction costs to hypothesize which services are more likely to be provided effectively. We then interpret the literature on PES programs to see the extent to which transaction costs vary as predicted across the type of service and to assess the performance of PES programs. As predicted, we find that transaction costs are the least for club goods like water and greatest for pure public goods like carbon reduction. Actual performance is difficult to measure and varies across the examples. More work and experimentation are needed to gain a better outlook on what elements support effective delivery of environmental services. PMID:25143798

Health behavior models and oral health: a review.

PubMed

Hollister, M Catherine; Anema, Marion G

2004-01-01

Dental hygienists help their clients develop health promoting behaviors, by providing essential information about general health, and oral health in particular. Individual health practices such as oral self-care are based on personal choices. The guiding principles found in health behavior models provide useful methods to the oral health care providers in promoting effective individual client behaviors. Theories provide explanations about observable facts in a systematic manner. Research regarding health behavior has explored the effectiveness and applicability of various health models in oral health behavior modification. The Health Belief Model, Transtheoretical Model and Stages of Change, Theory of Reasoned Action, Self-Efficacy, Locus of Control, and Sense of Coherence are examples of models that focus on individuals assuming responsibility for their own health. Understanding the strengths of each and their applicability to health behaviors is critical for oral health care providers who work with patients to adopt methods and modify behaviors that contribute to good oral health. This paper describes health behavior models that have been applied to oral health education, presents a critical analysis of the effectiveness of each model in oral health education, and provides examples of application to oral health education.

Just World Responding in 6- and 9-Year-Old Children

ERIC Educational Resources Information Center

Fein, Deborah

1976-01-01

This study examined the responses of kindergarten, first, third, and fourth grade girls to examples of good and bad behaviors followed either by good or bad outcomes. The results indicated that good behavior did not affect judgments of outcome but that a good outcome raised judgments of bad behavior. (JMB)

MISFITS: evaluating the goodness of fit between a phylogenetic model and an alignment.

PubMed

Nguyen, Minh Anh Thi; Klaere, Steffen; von Haeseler, Arndt

2011-01-01

As models of sequence evolution become more and more complicated, many criteria for model selection have been proposed, and tools are available to select the best model for an alignment under a particular criterion. However, in many instances the selected model fails to explain the data adequately as reflected by large deviations between observed pattern frequencies and the corresponding expectation. We present MISFITS, an approach to evaluate the goodness of fit (http://www.cibiv.at/software/misfits). MISFITS introduces a minimum number of "extra substitutions" on the inferred tree to provide a biologically motivated explanation why the alignment may deviate from expectation. These extra substitutions plus the evolutionary model then fully explain the alignment. We illustrate the method on several examples and then give a survey about the goodness of fit of the selected models to the alignments in the PANDIT database.

Injury and violence prevention: a primer.

PubMed

Gielen, Andrea Carlson

2002-03-01

Unintentional and intentional injuries cause a great deal of human suffering throughout the world. They exact a huge toll on societies in terms of mortality, years of potential life lost, disability, and health care costs. The good news is that great strides have been made in understanding the causes of injuries and how to prevent them. Using seat belts and car seats, installing air bags in cars, replacing dangerous playground equipment, enforcing drinking and driving laws are but a few examples of modifying behavior, products, and environments to reduce injury risk. This paper provides an overview of the science of injury control and selected examples of how professionals in the field of patient education and counseling can contribute to enhancing the safety of the public.

Cooled window for X-rays or charged particles

DOEpatents

Logan, Clinton M.

1996-01-01

A window that provides good structural integrity and a very high capacity for removal of the heat deposited by x-rays, electrons, or ions, with minimum attenuation of the desired beam. The window is cooled by providing microchannels therein through which a coolant is pumped. For example, the window may be made of silicon with etched microchannels therein and covered by a silicon member. A window made of silicon with a total thickness of 520 .mu.m transmits 96% of the x-rays at an energy of 60 keV, and the transmission is higher than 90% for higher energy photons.

Is diversity good? Six possible conceptions of diversity and six possible answers.

PubMed

Bouville, Mathieu

2008-03-01

Prominent ethical and policy issues such as affirmative action and female enrollment in science and engineering revolve around the idea that diversity is good. However, a precise definition is seldom provided. I show that diversity may be construed as a factual description, a craving for symmetry, an intrinsic good, an instrumental good, a symptom, or a side effect. These acceptions differ vastly in their nature and properties. Some are deeply mistaken and some others cannot lead to concrete policies. It is thus necessary to clarify what one means by 'diversity.' It may be a neutral description of a given state; but this is insufficient to act. The idea that there should be the same representation in a specific context as in the overall population is both puzzling and arbitrary. Diversity as intrinsic good is a mere opinion, which cannot be concretely applied; moreover, the most commonly invoked forms of diversity (sexual and racial) are not intrinsically good. On the other hand, diversity as instrumental good can be evaluated empirically and can give rise to policies, but these may be very weak. Finally, symptoms and side effects are not actually about diversity. I consider the example of female enrollment in science and engineering, interpreting the various arguments found in the literature in light of this polysemy.

Successfully using optical components and systems in novel ways during educational outreach programs for K-12 grades

NASA Astrophysics Data System (ADS)

Silberman, Donn

2006-08-01

Much work has been done in efforts to reach students in the K-12 grades to encourage them to learn about optics and related sciences and technologies. One goal of these efforts is to develop the future optical scientists and engineers to carry on the work of this and related societies. One main obstacle is to create low costs novel and effective hands-on optical components and systems for these students to use and from which to get excited. Students at different grade levels and abilities are receptive to different kinds of components and systems and this must be taken into account when preparing for outreach programs. There are, however, some guiding principles which can be used throughout the various levels, including making sure the components and systems are good examples and not marginal. Small telescopes or microscopes that use poor quality optics which provide poor quality images do more to discourage young students from going into the sciences than if they never had the experience at all. Some examples of both poor and good quality optical components and systems that will be described and demonstrated include: lenses, telescopes, microscopes, diffraction gratings, Kaleidoscopes, Fresnel Lenses, polarization filters and liquid crystals. The figures in this paper are in color and best viewed on-line or printed with a good color printer.

Findings From Existing Data on the Department of Defense Industrial Base: Guided Missile and Space Vehicle Manufacturing Example

DTIC Science & Technology

2015-04-30

FY 2012) FSRS and FPDS data can offer information on supplier dependency. Leading purchasing textbooks (e.g., Burt, Petcavage, & Pinkerton, 2010...FSRS, may show a different level of supplier dependency. Industry Subcontractor Dependence for Large (>$100 Million) Firms (FPDS-NG, FY 2010–FY...particular goods and services these subcontractors provide could better identify what level of risk supplier failure could pose by linking them to

Comparison of single and consecutive dual frequency induction surface hardening of gear wheels

NASA Astrophysics Data System (ADS)

Barglik, J.; Ducki, K.; Kukla, D.; Mizera, J.; Mrówka-Nowotnik, G.; Sieniawski, J.; Smalcerz, A.

2018-05-01

Mathematical modelling of single and consecutive dual - frequency induction surface hardening systems are presented and compared. The both models are solved by the 3D FEM-based professional software supported by a number of own numerical procedures. The methodology is illustrated with some examples of surface induction hardening of a gear wheel made of steel 41Cr4. The computations are in a good accordance with experiments provided on the laboratory stand.

Translations on Eastern Europe, Political, Sociological, and Military Affairs, Number 1393

DTIC Science & Technology

1977-05-26

that it cannot be assessed in its respective terms) is precisely pseudoscience or, stated more clearly, fraud. As a good example in which the lack of...possible. Professor Dobrin Spasov: Creativity and " Pseudoscience " I too think that our concern for greater scientific effectiveness must not be...directs us to say something about " pseudoscience ." I shall not attempt to provide a strict definition of pseudoscience . Obvi- ously, it is something

The Art of Reflection: Turning the Strange into the Familiar.

PubMed

Weingarten, Kaethe

2016-06-01

There are a great many useful articles on the dynamics and pragmatics of reflecting teams but few articles address what constitutes a good or inept reflection and why. I provide a conceptual model for thinking about what a good reflection does, distinguishing it from a nice reflection. With some further refinements in place, I then illustrate how reflections can be part of any relationship, not just clinical ones. We have opportunities to make them and to recognize when others make them to us. By using examples from my personal life-as a grandmother, daughter, radio listener, cancer survivor, and client-I attempt to ease the personal/professional binary, a project of mine for the last 35 years. In the second part of the article, I address how writing can serve reflection. Although best offered at the moment one is called for, it is never too late for a reflection. Writing allows people to offer reflections after the fact to those who have shared their stories. Sometimes, it is to ourselves we offer those reflections, when the reflector has long since dropped the thread of obligation or interest. I provide an example of working with iconic imagery to unpack meaning so that reflection can eventually take place, allowing integration to proceed, facilitating the strange becoming the familiar. © 2015 Family Process Institute.

Local residue coupling strategies by neural network for InSAR phase unwrapping

NASA Astrophysics Data System (ADS)

Refice, Alberto; Satalino, Giuseppe; Chiaradia, Maria T.

1997-12-01

Phase unwrapping is one of the toughest problems in interferometric SAR processing. The main difficulties arise from the presence of point-like error sources, called residues, which occur mainly in close couples due to phase noise. We present an assessment of a local approach to the resolution of these problems by means of a neural network. Using a multi-layer perceptron, trained with the back- propagation scheme on a series of simulated phase images, fashion the best pairing strategies for close residue couples. Results show that god efficiencies and accuracies can have been obtained, provided a sufficient number of training examples are supplied. Results show that good efficiencies and accuracies can be obtained, provided a sufficient number of training examples are supplied. The technique is tested also on real SAR ERS-1/2 tandem interferometric images of the Matera test site, showing a good reduction of the residue density. The better results obtained by use of the neural network as far as local criteria are adopted appear justified given the probabilistic nature of the noise process on SAR interferometric phase fields and allows to outline a specifically tailored implementation of the neural network approach as a very fast pre-processing step intended to decrease the residue density and give sufficiently clean images to be processed further by more conventional techniques.

United States import safety, environmental health, and food safety regulation in China.

PubMed

Nyambok, Edward O; Kastner, Justin J

2012-01-01

China boasts a rapidly growing economy and is a leading food exporter. Since China has dominated world export markets in food, electronics, and toys, many safety concerns about Chinese exports have emerged. For example, many countries have had problems with Chinese food products and food-processing ingredients. Factors behind food safety and environmental health problems in China include poor industrial waste management, the use of counterfeit agricultural inputs, inadequate training of farmers on good farm management practices, and weak food safety laws and poor enforcement. In the face of rising import safety problems, the U.S. is now requiring certification of products and foreign importers, pursuing providing incentives to importers who uphold good safety practices, and considering publicizing the names of certified importers.

Computer validation in toxicology: historical review for FDA and EPA good laboratory practice.

PubMed

Brodish, D L

1998-01-01

The application of computer validation principles to Good Laboratory Practice is a fairly recent phenomenon. As automated data collection systems have become more common in toxicology facilities, the U.S. Food and Drug Administration and the U.S. Environmental Protection Agency have begun to focus inspections in this area. This historical review documents the development of regulatory guidance on computer validation in toxicology over the past several decades. An overview of the components of a computer life cycle is presented, including the development of systems descriptions, validation plans, validation testing, system maintenance, SOPs, change control, security considerations, and system retirement. Examples are provided for implementation of computer validation principles on laboratory computer systems in a toxicology facility.

Water surface modeling from a single viewpoint video.

PubMed

Li, Chuan; Pickup, David; Saunders, Thomas; Cosker, Darren; Marshall, David; Hall, Peter; Willis, Philip

2013-07-01

We introduce a video-based approach for producing water surface models. Recent advances in this field output high-quality results but require dedicated capturing devices and only work in limited conditions. In contrast, our method achieves a good tradeoff between the visual quality and the production cost: It automatically produces a visually plausible animation using a single viewpoint video as the input. Our approach is based on two discoveries: first, shape from shading (SFS) is adequate to capture the appearance and dynamic behavior of the example water; second, shallow water model can be used to estimate a velocity field that produces complex surface dynamics. We will provide qualitative evaluation of our method and demonstrate its good performance across a wide range of scenes.

Modeling of geographical pricing: A game analysis of siberian fuel costs

NASA Astrophysics Data System (ADS)

Sivushina, Anastasiya; Kombu, Anchy; Ryumkin, Valeriy

2017-11-01

In the present study, we propose a novel game-theoretic pricing model describing the interaction between producers and retailers of goods in conditions of poor transport infrastructure and sparse geographical distribution of the points of sale. The proposed model generalizes the Stackelberg leadership model for an arbitrary number of leaders and followers. We show that the model always has a Nash and Stackelberg equilibria. We also provide formulas for the equilibrium prices and volume of sales. As an example we model diesel pricing in south Siberia. Our model found no signs of a cartel. The results of this paper can be used by policymakers to inform market regulations aimed at promoting free competition and avoiding monopolies in production and retail of goods.

Multiple Criteria Decision Analysis for Health Care Decision Making--An Introduction: Report 1 of the ISPOR MCDA Emerging Good Practices Task Force.

PubMed

Thokala, Praveen; Devlin, Nancy; Marsh, Kevin; Baltussen, Rob; Boysen, Meindert; Kalo, Zoltan; Longrenn, Thomas; Mussen, Filip; Peacock, Stuart; Watkins, John; Ijzerman, Maarten

2016-01-01

Health care decisions are complex and involve confronting trade-offs between multiple, often conflicting, objectives. Using structured, explicit approaches to decisions involving multiple criteria can improve the quality of decision making and a set of techniques, known under the collective heading multiple criteria decision analysis (MCDA), are useful for this purpose. MCDA methods are widely used in other sectors, and recently there has been an increase in health care applications. In 2014, ISPOR established an MCDA Emerging Good Practices Task Force. It was charged with establishing a common definition for MCDA in health care decision making and developing good practice guidelines for conducting MCDA to aid health care decision making. This initial ISPOR MCDA task force report provides an introduction to MCDA - it defines MCDA; provides examples of its use in different kinds of decision making in health care (including benefit risk analysis, health technology assessment, resource allocation, portfolio decision analysis, shared patient clinician decision making and prioritizing patients' access to services); provides an overview of the principal methods of MCDA; and describes the key steps involved. Upon reviewing this report, readers should have a solid overview of MCDA methods and their potential for supporting health care decision making. Copyright © 2016. Published by Elsevier Inc.

NASA Handbook for Models and Simulations: An Implementation Guide for NASA-STD-7009

NASA Technical Reports Server (NTRS)

Steele, Martin J.

2013-01-01

The purpose of this Handbook is to provide technical information, clarification, examples, processes, and techniques to help institute good modeling and simulation practices in the National Aeronautics and Space Administration (NASA). As a companion guide to NASA-STD- 7009, Standard for Models and Simulations, this Handbook provides a broader scope of information than may be included in a Standard and promotes good practices in the production, use, and consumption of NASA modeling and simulation products. NASA-STD-7009 specifies what a modeling and simulation activity shall or should do (in the requirements) but does not prescribe how the requirements are to be met, which varies with the specific engineering discipline, or who is responsible for complying with the requirements, which depends on the size and type of project. A guidance document, which is not constrained by the requirements of a Standard, is better suited to address these additional aspects and provide necessary clarification. This Handbook stems from the Space Shuttle Columbia Accident Investigation (2003), which called for Agency-wide improvements in the "development, documentation, and operation of models and simulations"' that subsequently elicited additional guidance from the NASA Office of the Chief Engineer to include "a standard method to assess the credibility of the models and simulations."2 General methods applicable across the broad spectrum of model and simulation (M&S) disciplines were sought to help guide the modeling and simulation processes within NASA and to provide for consistent reporting ofM&S activities and analysis results. From this, the standardized process for the M&S activity was developed. The major contents of this Handbook are the implementation details of the general M&S requirements ofNASA-STD-7009, including explanations, examples, and suggestions for improving the credibility assessment of an M&S-based analysis.

Expanded Benefits for Humanity from the International Space Station

NASA Technical Reports Server (NTRS)

Rai, Amelia; Robinson, Julie A.; Tate-Brown, Judy; Buckley, Nicole; Zell, Martin; Tasaki, Kazuyuki; Karabadzhak, Georgy; Sorokin, Igor V.; Pignataro, Salvatore

2016-01-01

In 2012, the International Space Station (ISS) partnership published the updated International Space Station Benefits for Humanity, 2nd edition, a compilation of stories about the many benefits being realized in the areas of human health, Earth observations and disaster response, and global education. This compilation has recently been revised to include updated statistics on the impacts of the benefits, and new benefits that have developed since the first publication. Two new sections have also been added to the book, economic development of space and innovative technology. This paper will summarize the updates on behalf of the ISS Program Science Forum, made up of senior science representatives across the international partnership. The new section on "Economic Development of Space" highlights case studies from public-private partnerships that are leading to a new economy in low earth orbit (LEO). Businesses provide both transportation to the ISS as well as some research facilities and services. These relationships promote a paradigm shift of government-funded, contractor-provided goods and services to commercially-provided goods purchased by government agencies. Other examples include commercial firms spending research and development dollars to conduct investigations on ISS and commercial service providers selling services directly to ISS users. This section provides examples of ISS as a test bed for new business relationships, and illustrates successful partnerships. The second new section, Innovative Technology, merges technology demonstration and physical science findings that promise to return Earth benefits through continued research. Robotic refueling concepts for life extensions of costly satellites in geo-synchronous orbit have applications to robotics in industry on Earth. Flame behavior experiments reveal insight into how fuel burns in microgravity leading to the possibility of improving engine efficiency on Earth. Nanostructures and smart fluids are examples of materials improvements that are being developed using data from ISS. The publication also expands the benefits of research results in human health, environmental change and disaster response and in education activities developed to capture student imaginations in support of science, technology, engineering and mathematics, or STEM, education internationally. Applications to human health of the knowledge gained on ISS continues to grow and improve healthcare technologies and our understanding of human physiology. Distinct benefits return to Earth from the only orbiting multi-disciplinary laboratory of its kind. The ISS is a stepping stone for future space exploration by providing findings that develop LEO and improve life on our planet.

Expanded benefits for humanity from the International Space Station

NASA Astrophysics Data System (ADS)

Rai, Amelia; Robinson, Julie A.; Tate-Brown, Judy; Buckley, Nicole; Zell, Martin; Tasaki, Kazuyuki; Karabadzhak, Georgy; Sorokin, Igor V.; Pignataro, Salvatore

2016-09-01

In 2012, the International Space Station (ISS) (Fig. 1) partnership published the updated International Space Station Benefits for Humanity[1], a compilation of stories about the many benefits being realized in the areas of human health, Earth observations and disaster response, and global education. This compilation has recently been revised to include updated statistics on the impacts of the benefits, and new benefits that have developed since the first publication. Two new sections have also been added to the book, economic development of space and innovative technology. This paper will summarize the updates on behalf of the ISS Program Science Forum, made up of senior science representatives across the international partnership. The new section on "Economic Development of Space" highlights case studies from public-private partnerships that are leading to a new economy in low earth orbit (LEO). Businesses provide both transportation to the ISS as well as some research facilities and services. These relationships promote a paradigm shift of government-funded, contractor-provided goods and services to commercially-provided goods purchased by government agencies. Other examples include commercial firms spending research and development dollars to conduct investigations on ISS and commercial service providers selling services directly to ISS users. This section provides examples of ISS as a test bed for new business relationships, and illustrates successful partnerships. The second new section, "Innovative Technology," merges technology demonstration and physical science findings that promise to return Earth benefits through continued research. Robotic refueling concepts for life extensions of costly satellites in geo-synchronous orbit have applications to robotics in industry on Earth. Flame behavior experiments reveal insight into how fuel burns in microgravity leading to the possibility of improving engine efficiency on Earth. Nanostructures and smart fluids are examples of materials improvements that are being developed using data from ISS. The publication also expands the benefits of research results in human health, environmental change and disaster response and in education activities developed to capture student imaginations in support of science, technology, engineering and mathematics, or STEM, education internationally. Applications to human health of the knowledge gained on ISS continue to grow and improve healthcare technologies and our understanding of human physiology. Distinct benefits return to Earth from the only orbiting multi-disciplinary laboratory of its kind. The ISS is a stepping stone for future space exploration by providing findings that develop LEO and improve life on our planet.

31 CFR 545.408 - Offshore transactions.

Code of Federal Regulations, 2010 CFR

2010-07-01

...) With respect to goods, software, technology, or services which the U.S. person knows, or has reason to... States of goods, software, technology or services owned or controlled by the Taliban or persons whose... dealing in such blocked goods, software, technology, or services. (c) Example. A U.S. person may not...

Evaluating patient-reported outcome measurement comparability between paper and alternate versions, using the lung function questionnaire as an example.

PubMed

Dalal, Anand A; Nelson, Lauren; Gilligan, Theresa; McLeod, Lori; Lewis, Sandy; DeMuro-Mercon, Carla

2011-01-01

The goal of this study was to provide recommended steps to assess measurement comparability using a crossover study design and to demonstrate these steps using a short patient-reported outcome (PRO) instrument as an example. The example PRO instrument was administered via paper, Web, interactive voice response system, and interview; a randomized crossover design was used to gather data across the multiple administration types. Participants completed the PRO instrument, demographic and health questions, and a short preference questionnaire. Evaluation included comparisons of the item-level responses and agreement, comparison of mean scale scores, score classifications, and questions designed to collect usability and administration preference. Here the authors provide a four-step evaluation guide to evaluate measurement comparability and illustrate these steps using a case-finding tool. In the example, item-level kappa statistics between the paper and the alternate versions ranged from good to excellent, intraclass correlation coefficient for mean scores were above 0.70, and the rate of disagreement ranged from 2% to 14%. In addition, although participants had an administration preference, they reported few difficulties with the versions they were assigned. The steps described in this article provide a guide for evaluating whether to combine scores across administration versions to simplify analyses and interpretation under a crossover design. The guide recommends the investigation of item-level responses, summary scores, and participant usability/preference when comparing versions, with each step providing unique information to support comprehensive evaluation and informed decisions regarding whether to combine data. Copyright © 2011 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

Knowledge for the good of the individual and society: linking philosophy, disciplinary goals, theory, and practice.

PubMed

McCurry, Mary K; Revell, Susan M Hunter; Roy, Sr Callista

2010-01-01

Nursing as a profession has a social mandate to contribute to the good of society through knowledge-based practice. Knowledge is built upon theories, and theories, together with their philosophical bases and disciplinary goals, are the guiding frameworks for practice. This article explores a philosophical perspective of nursing's social mandate, the disciplinary goals for the good of the individual and society, and one approach for translating knowledge into practice through the use of a middle-range theory. It is anticipated that the integration of the philosophical perspective and model into nursing practice will strengthen the philosophy, disciplinary goal, theory, and practice links and expand knowledge within the discipline. With the focus on humanization, we propose that nursing knowledge for social good will embrace a synthesis of the individual and the common good. This approach converges vital and agency needs described by Hamilton and the primacy of maintaining the heritage of the good within the human species as outlined by Maritain. Further, by embedding knowledge development in a changing social and health care context, nursing focuses on the goals of clinical reasoning and action. McCubbin and Patterson's Double ABCX Model of Family Adaptation was used as an example of a theory that can guide practice at the community and global level. Using the theory-practice link as a foundation, the Double ABCX model provides practising nurses with one approach to meet the needs of individuals and society. The integration of theory into nursing practice provides a guide to achieve nursing's disciplinary goals of promoting health and preventing illness across the globe. When nursing goals are directed at the synthesis of the good of the individual and society, nursing's social and moral mandate may be achieved.

Teaching Basic Probability in Undergraduate Statistics or Management Science Courses

ERIC Educational Resources Information Center

Naidu, Jaideep T.; Sanford, John F.

2017-01-01

Standard textbooks in core Statistics and Management Science classes present various examples to introduce basic probability concepts to undergraduate business students. These include tossing of a coin, throwing a die, and examples of that nature. While these are good examples to introduce basic probability, we use improvised versions of Russian…

Effects of Barometric Fluctuations on Well Water-Level Measurements and Aquifer Test Data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Spane, Frank A.

1999-12-16

This report examines the effects of barometric fluctuations on well water-level measurements and evaluates adjustment and removal methods for determining areal aquifer head conditions and aquifer test analysis. Two examples of Hanford Site unconfined aquifer tests are examined that demonstrate baro-metric response analysis and illustrate the predictive/removal capabilities of various methods for well water-level and aquifer total head values. Good predictive/removal characteristics were demonstrated with best corrective results provided by multiple-regression deconvolution methods.

Expanding Participation in Fluid Dynamics Research

NASA Astrophysics Data System (ADS)

Tagg, Randall

2015-11-01

Two legacies provided by great scientists are scientific discoveries and more scientists. Is there a way that these impacts can be magnified? Examples using the Taylor-Couette experiment and other fluid dynamics problems will demonstrate that indeed more people can fruitfully engage in open and even bold investigation. Participants include high school students, teachers, undergraduates, artists, business developers and interested laypersons. With imagination, good training, and a suitable lab space, a special tribute can be given to those who mentor us by scaling up the breadth of their influence.

Acquisition of Earth Science Remote Sensing Observations from Commercial Sources: Lessons Learned from the Space Imaging IKONOS Example

NASA Technical Reports Server (NTRS)

Goward, Samuel N.; Townshend, John R.; Zanoni, Vicki; Policelli, Fritz; Stanley, Tom; Ryan, Robert; Holekamp, Kara; Underwood, Lauren; Pagnutti, Mary; Fletcher, Rose

2003-01-01

In an effort to more full explore the potential of commercial remotely sensed land data sources, the NASA Earth Science Enterprise (ESE) implemented an experimental Scientific Data Purchase (SDP) that solicited bids from the private sector to meet ESE-user data needs. The images from the Space Imaging IKONOS system provided a particularly good match to the current ESE missions such as Terra and Landsat 7 and therefore serve as a focal point in this analysis.

The study of molecular spectroscopy by ab initio methods

NASA Technical Reports Server (NTRS)

Bauschlicher, Charles W., Jr.; Langhoff, Stephen R.

1991-01-01

This review illustrates the potential of theory for solving spectroscopic problems. The accuracy of approximate techniques for including electron correlation have been calibrated by comparison with full configuration-interaction calculations. Examples of the application of ab initio calculations to vibrational, rotational, and electronic spectroscopy are given. It is shown that the state-averaged, complete active space self-consistent field, multireference configuration-interaction procedure provides a good approach for treating several electronic states accurately in a common molecular orbital basis.

The Brazilian Air Force Uniform Distribution Process: Using Lean Thinking, Statistical Process Control and Theory of Constraints to Address Improvement Opportunities

DTIC Science & Technology

2015-03-26

universal definition” (Evans & Lindsay, 1996). Heizer and Render (2010) argue that several definitions of this term are user-based, meaning, that quality...for example, really good ice cream has high butterfat levels.” ( Heizer & Render , 2010). Garvin, in his Competing in Eight Dimensions of Quality...Montgomery, 2005). As for definition purposes, the concept adopted by this research was provided by Heizer and Render (2010), for whom Statistical Process

Vegetation Phenology Metrics Derived from Temporally Smoothed and Gap-filled MODIS Data

NASA Technical Reports Server (NTRS)

Tan, Bin; Morisette, Jeff; Wolfe, Robert; Esaias, Wayne; Gao, Feng; Ederer, Greg; Nightingale, Joanne; Nickeson, Jamie E.; Ma, Pete; Pedely, Jeff

2012-01-01

Smoothed and gap-filled VI provides a good base for estimating vegetation phenology metrics. The TIMESAT software was improved by incorporating the ancillary information from MODIS products. A simple assessment of the association between retrieved greenup dates and ground observations indicates satisfactory result from improved TIMESAT software. One application example shows that mapping Nectar Flow Phenology is tractable on a continental scale using hive weight and satellite vegetation data. The phenology data product is supporting more researches in ecology, climate change fields.

Lanthanum halide scintillators for time-of-flight 3-D pet

DOEpatents

Karp, Joel S [Glenside, PA; Surti, Suleman [Philadelphia, PA

2008-06-03

A Lanthanum Halide scintillator (for example LaCl.sub.3 and LaBr.sub.3) with fast decay time and good timing resolution, as well as high light output and good energy resolution, is used in the design of a PET scanner. The PET scanner includes a cavity for accepting a patient and a plurality of PET detector modules arranged in an approximately cylindrical configuration about the cavity. Each PET detector includes a Lanthanum Halide scintillator having a plurality of Lanthanum Halide crystals, a light guide, and a plurality of photomultiplier tubes arranged respectively peripherally around the cavity. The good timing resolution enables a time-of-flight (TOF) PET scanner to be developed that exhibits a reduction in noise propagation during image reconstruction and a gain in the signal-to-noise ratio. Such a PET scanner includes a time stamp circuit that records the time of receipt of gamma rays by respective PET detectors and provides timing data outputs that are provided to a processor that, in turn, calculates time-of-flight (TOF) of gamma rays through a patient in the cavity and uses the TOF of gamma rays in the reconstruction of images of the patient.

How Is PTSD Measured?

MedlinePlus

... a good choice for a particular evaluation. Self-report Questionnaires A self-report questionnaire is a set of questions, usually printed ... than an interview. An example of a self-report measure is: An example of a self-report ...

Human errors and measurement uncertainty

NASA Astrophysics Data System (ADS)

Kuselman, Ilya; Pennecchi, Francesca

2015-04-01

Evaluating the residual risk of human errors in a measurement and testing laboratory, remaining after the error reduction by the laboratory quality system, and quantifying the consequences of this risk for the quality of the measurement/test results are discussed based on expert judgments and Monte Carlo simulations. A procedure for evaluation of the contribution of the residual risk to the measurement uncertainty budget is proposed. Examples are provided using earlier published sets of expert judgments on human errors in pH measurement of groundwater, elemental analysis of geological samples by inductively coupled plasma mass spectrometry, and multi-residue analysis of pesticides in fruits and vegetables. The human error contribution to the measurement uncertainty budget in the examples was not negligible, yet also not dominant. This was assessed as a good risk management result.

Extraction and Analysis of Traditional Chinese Medicine Crops Based on Multitemporal High Resolution Data-Taking Qiaocheng District of Bozhou as AN Example

NASA Astrophysics Data System (ADS)

Yu, H.; He, J.; Zhou, H.; Guan, F.; Li, L.; Ren, B.; Wang, Z.

2018-04-01

Remote sensing technology has become an important method to rapidly acquireing of planting layout and composition of regional crops.It is very important to accurately master the planting area of Chinese medicine crops in the Characteristic planting area because it relations to accurately master the cultivation of Chinese medicine crops, formulate related policies and adjustment of crop planting structure.The author puts forward a method of using remote sencing technology for momitoring Chinese medicine which has good applicability and generalization. This paper took Qiaocheng District of Bozhou as an example to Verify the feasibility of the method, providing a reference for solving the problem of interpretation and extraction of Chinese medicinal materials in the region.

ODEion--a software module for structural identification of ordinary differential equations.

PubMed

Gennemark, Peter; Wedelin, Dag

2014-02-01

In the systems biology field, algorithms for structural identification of ordinary differential equations (ODEs) have mainly focused on fixed model spaces like S-systems and/or on methods that require sufficiently good data so that derivatives can be accurately estimated. There is therefore a lack of methods and software that can handle more general models and realistic data. We present ODEion, a software module for structural identification of ODEs. Main characteristic features of the software are: • The model space is defined by arbitrary user-defined functions that can be nonlinear in both variables and parameters, such as for example chemical rate reactions. • ODEion implements computationally efficient algorithms that have been shown to efficiently handle sparse and noisy data. It can run a range of realistic problems that previously required a supercomputer. • ODEion is easy to use and provides SBML output. We describe the mathematical problem, the ODEion system itself, and provide several examples of how the system can be used. Available at: http://www.odeidentification.org.

What is good governance in the context of drug policy?

PubMed

Singleton, Nicola; Rubin, Jennifer

2014-09-01

The concept of governance is applied in a wide range of contexts, but this paper focuses on governance in relation to public administration, i.e. states and how they take action, and specifically governance of particular policy areas. In the current context of financial austerity and an era of globalisation, policy-makers face pressures and challenges from a growing range of interests and local, national and supranational actors. Drug policy is an example of a particularly contentious and polarised area in which governance-related challenges abound. In response to these challenges, interest has grown in developing agreed policy governance standards and processes and articulating policy-making guidelines, including the use of available evidence to inform policy-making. Attempts have been made to identify 'policy fundamentals' - factors or aspects of policy-making apparently associated with successful policy development and implementation (Hallsworth & Rutter, 2011; Laughrin, 2011) and, in the drug policy field, Hughes et al. (2010) reflecting on the co-ordination of Australian drug policy highlighted some of what they considered principles of good governance. But how useful is the concept of 'good governance'; how well can it be defined, and to what purpose? As part of a wider project considering the governance of drug policy, RAND Europe and the UK Drug Policy Commission undertook a targeted review of other research and sought expert views, from within and beyond drug policy, on principles, processes, structures and stakeholders associated with good drug policy governance. From this emerged some perceived characteristics of good governance that were then used by the UK Drug Policy Commission to assess the extent to which drug policy making in the UK fits with these perceived good governance characteristics, and to suggest possible improvements. Particular consideration was given to the range of interests at stake, the overarching aims of drug policy and the development and inclusion of an evidence base where possible. This paper draws on findings of the study to highlight challenges associated with defining good governance, provides an example of a framework for assessing drug policy governance and discusses the feasibility, transferability and potential benefits of such an undertaking. Copyright © 2014 Elsevier B.V. All rights reserved.

Definitions of Complexity are Notoriously Difficult

NASA Astrophysics Data System (ADS)

Schuster, Peter

Definitions of complexity are notoriously difficult if not impossible at all. A good working hypothesis might be: Everything is complex that is not simple. This is precisely the way in which we define nonlinear behavior. Things appear complex for different reasons: i) Complexity may result from lack of insight, ii) complexity may result from lack of methods, and (iii) complexity may be inherent to the system. The best known example for i) is celestial mechanics: The highly complex Pythagorean epicycles become obsolete by the introduction of Newton's law of universal gravitation. To give an example for ii), pattern formation and deterministic chaos became not really understandable before extensive computer simulations became possible. Cellular metabolism may serve as an example for iii) and is caused by the enormous complexity of biochemical reaction networks with up to one hundred individual reaction fluxes. Nevertheless, only few fluxes are dominant in the sense that using Pareto optimal values for them provides near optimal values for all the others...

Evaluation and audit in a paediatric disability service.

PubMed Central

Cass, H D; Kugler, B T

1993-01-01

Parental and professional responses to questionnaires evaluating a paediatric disability service are reported and the viability of auditing structural, process, and outcome aspects of clinical practice are discussed. Expectations of waiting time to first appointment (met for only 52% of consumers) illustrate structural issues. Process issues are reflected in consumer reactions to outreach work (for example, 94% of parents and 84% of professionals found this supportive). Outcome measures such as consumer satisfaction with the service (76% of consumers reported being 'very satisfied' and 20% 'fairly satisfied') suggest that service aims are being met. Good concurrence of service aims with consumer needs is indicated by parental reasons for referral (for example, 75% for diagnostic help, 73% for a better understanding of the disorder, 88% for practical help), referrers' reasons (for example, 55% for a second diagnostic opinion, 45% due to lack of local expertise), and reports from most other professionals involved with the case that a similar service was not provided locally. PMID:8466242

Evaluation and audit in a paediatric disability service.

PubMed

Cass, H D; Kugler, B T

1993-03-01

Parental and professional responses to questionnaires evaluating a paediatric disability service are reported and the viability of auditing structural, process, and outcome aspects of clinical practice are discussed. Expectations of waiting time to first appointment (met for only 52% of consumers) illustrate structural issues. Process issues are reflected in consumer reactions to outreach work (for example, 94% of parents and 84% of professionals found this supportive). Outcome measures such as consumer satisfaction with the service (76% of consumers reported being 'very satisfied' and 20% 'fairly satisfied') suggest that service aims are being met. Good concurrence of service aims with consumer needs is indicated by parental reasons for referral (for example, 75% for diagnostic help, 73% for a better understanding of the disorder, 88% for practical help), referrers' reasons (for example, 55% for a second diagnostic opinion, 45% due to lack of local expertise), and reports from most other professionals involved with the case that a similar service was not provided locally.

Comparison of patient evaluations of health care quality in relation to WHO measures of achievement in 12 European countries.

PubMed

Kerssens, Jan J; Groenewegen, Peter P; Sixma, Herman J; Boerma, Wienke G W; van der Eijk, Ingrid

2004-02-01

To gain insight into similarities and differences in patient evaluations of quality of primary care across 12 European countries and to correlate patient evaluations with WHO health system performance measures (for example, responsiveness) of these countries. Patient evaluations were derived from a series of Quote (QUality of care Through patients' Eyes) instruments designed to measure the quality of primary care. Various research groups provided a total sample of 5133 patients from 12 countries: Belarus, Denmark, Finland, Greece, Ireland, Israel, Italy, the Netherlands, Norway, Portugal, United Kingdom, and Ukraine. Intraclass correlations of 10 Quote items were calculated to measure differences between countries. The world health report 2000 - Health systems: improving performance performance measures in the same countries were correlated with mean Quote scores. Intra-class correlation coefficients ranged from low to very high, which indicated little variation between countries in some respects (for example, primary care providers have a good understanding of patients' problems in all countries) and large variation in other respects (for example, with respect to prescription of medication and communication between primary care providers). Most correlations between mean Quote scores per country and WHO performance measures were positive. The highest correlation (0.86) was between the primary care provider's understanding of patients' problems and responsiveness according to WHO. Patient evaluations of the quality of primary care showed large differences across countries and related positively to WHO's performance measures of health care systems.

Allylic Amination and N-Arylation-Based Domino Reactions Providing Rapid Three-Component Strategies to Fused Pyrroles with Different Substituted Patterns

PubMed Central

Jiang, Bo; Li, Ying; Tu, Man-Su; Wang, Shu-Liang; Tu, Shu-Jiang; Li, Guigen

2012-01-01

New three-component domino reaction providing divergent approaches to multi-functionalized fused pyrroles with different substituted patterns have been established (40 examples). The direct C(sp3)–N bond formation was achieved through intermolecular allylic amination in a one-pot operation; and N-arylation of amines was realized by varying N-amino acid enaminones. The reaction is easy to perform simply by mixing three common reactants in acetic acid under microwave heating. The reaction proceeds at fast rates and can be finished within 30 min, which makes workup convenient to give good chemical yields. PMID:22852549

Planning and management of science programs on Skylab

NASA Technical Reports Server (NTRS)

Parker, R. A. R.; Sevier, J. R.

1974-01-01

Discussion of the experience gained in experiment operation planning during the Skylab mission. The Skylab flight planning activity allowed the experimenters to interact with the system and provided the flexibility to respond to contingencies both major and minor. Both these aspects contributed to make efficient use of crew time thus helping to increase the science return from the mission. Examples of the need for real time scheduling response and of the tradeoffs considered between conflicting experiment requirements are presented. General management principles derived from this experience are developed. The Skylab mission experiences, together with previous Apollo mission experiences, are shown to provide a good background for Shuttle flight planning.

Peer-mentoring Program during the Preclinical Years of Medical School at Bonn University: a Project Description.

PubMed

Lapp, Hendrik; Makowka, Philipp; Recker, Florian

2018-01-01

Introduction: To better prepare young medical students in a thorough and competent manner for the ever increasing clinical, scientific, as well as psychosocial requirements, universities should enable a close, personal transfer of experience and knowledge. Structured mentoring programs are a promising approach to incorporate clinical subjects earlier into the preclinical training. Such a mentoring program facilitates the prioritization of concepts from a broad, theory-heavy syllabus. Here we report the experiences and results of the preclinical mentoring program of Bonn University, which was introduced in the winter semester of 2012/2013. Project desciption: The program is characterized by the concept of peer-to-peer teaching during the preclinical semesters of medical school. Regular, voluntary course meetings with different clinical case examples provide students the opportunity to apply knowledge acquired from the basic science curricula; furthermore, a personal contact for advice and support is ensured. Thus, an informal exchange of experiences is made possible, which provides to the students motivational and learning aids, in particular for the oral examination at the end of the premedical semesters as well as for other examinations during medical school. Results: Over the course of the preceding three years the number of participants and the interest in the program grew steadily. The analysis of collected evaluations confirms very good communication between mentors and students (>80%), as well as consistently good to very good quality and usefulness in terms of the mentors' subject-specific and other advice. The overall final evaluation of the mentoring program was always good to very good (winter semester: very good 64.8±5.0%, good 35.2±5.0%, summer semester: very good 83.9±7.5%, good 16.1±7.5%) Summary: In summary, it has been shown that the mentoring program had a positive impact on the development, education and satisfaction of students beginning their preclinical semesters at Bonn University.

Good Teachers, Good Schools: How to Create a Successful School

ERIC Educational Resources Information Center

Hudson, David

2009-01-01

"Good schools think 'with' people and not 'to' people" argues David Hudson in this thought provoking practical guide for those wanting to bridge the gap between middle and senior management roles, and make a difference in their schools. Accessibly and engagingly written and packed with real-life examples, this book will prove essential…

Mentoring Graduate Students: The Good, Bad, and Gray

ERIC Educational Resources Information Center

Ballantine, Jeanne H.; Jolly-Ballantine, John-Andrew

2015-01-01

Good mentoring of graduate students influences their perseverance and success to completion, whereas bad mentoring can result in negative outcomes, including delayed degree completion or non-completion. What the authors refer to as the gray zone is that which falls between good and bad mentoring. Examples are partial mentoring or changes in…

Writing for Primary Science

ERIC Educational Resources Information Center

Mawby, Tara, Ed.

2011-01-01

In this article, two short pieces are presented to show educators just what a good article and a good review could have in them. This article has been written for the purpose of illustrating a good example, but is also representative of the type of content the editors encourage in "Primary Science": practical and active, with images. They also…

Time perception: the bad news and the good

PubMed Central

Matthews, William J; Meck, Warren H

2014-01-01

Time perception is fundamental and heavily researched, but the field faces a number of obstacles to theoretical progress. In this advanced review, we focus on three pieces of ‘bad news’ for time perception research: temporal perception is highly labile across changes in experimental context and task; there are pronounced individual differences not just in overall performance but in the use of different timing strategies and the effect of key variables; and laboratory studies typically bear little relation to timing in the ‘real world’. We describe recent examples of these issues and in each case offer some ‘good news’ by showing how new research is addressing these challenges to provide rich insights into the neural and information-processing bases of timing and time perception. PMID:25210578

Fitting a three-parameter lognormal distribution with applications to hydrogeochemical data from the National Uranium Resource Evaluation Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kane, V.E.

1979-10-01

The standard maximum likelihood and moment estimation procedures are shown to have some undesirable characteristics for estimating the parameters in a three-parameter lognormal distribution. A class of goodness-of-fit estimators is found which provides a useful alternative to the standard methods. The class of goodness-of-fit tests considered include the Shapiro-Wilk and Shapiro-Francia tests which reduce to a weighted linear combination of the order statistics that can be maximized in estimation problems. The weighted-order statistic estimators are compared to the standard procedures in Monte Carlo simulations. Bias and robustness of the procedures are examined and example data sets analyzed including geochemical datamore » from the National Uranium Resource Evaluation Program.« less

Good is not good enough: the culture of low expectations and the leader's challenge.

PubMed

Kerfoot, Karlene M

2010-01-01

There are many examples of health care organizations that have morphed from the culture of low expectation to the culture of excellence. Ethically, to not drive to excellence means that we are settling from knowingly allowing harm to happen on our watch. The leader's obligation is to create that sonic boom that Black and Gregersen (2008) describe to break up the old mind maps, to create the movement, and to finish the cultural change in spite of change fatigue and other factors that could sabotage the process. Only then can the effective leader sleep well at night knowing that the infrastructure is being created that will provide a culture of excellence and safety for patients and their families. And it is being created on his/her watch.

What is it to do good medical ethics? From the perspective of a practising doctor who is in Parliament.

PubMed

Finlay, Ilora G

2015-01-01

This article is a personal reflection on work as a physician with work as a member of the UK Parliament's House of Lords. Ethical thinking should underpin everything we do; the 'four principles' of medical ethics provide an applicable and relevant ethical framework. This article explores its application in both domains of work-as a clinician and as a legislator-with some examples of its use 'to do good medical ethics' in both roles. Debates around tobacco and drug control, pandemic control, abortion and assisted suicide are explored. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Self-Explanations: How Students Study and Use Examples in Learning To Solve Problems. Technical Report No. 9.

ERIC Educational Resources Information Center

Chi, Michelene T. H.; And Others

A study examined in detail the initial encoding of worked-out examples of mechanics problems by "good" and "poor" students, and their subsequent reliance on examples during problem solving. The subjects, three males and five females, were selected from responses to a university campus advertisement. Six of them were working…

Practice-audit-publish: A practice reflection.

PubMed

Ferrari, Robert

2016-12-01

Practice audits are useful opportunities to improve practice efficiency and effectiveness, reduce clinical errors, demonstrate quality care to stakeholders, promote high standards of practice, lower the risk of liability, and foster practice change. However, a benefit that is usually overlooked is the possibility of publication of the results of a practice audit. Publication (research) has a number of benefits for the clinician, including skill development as a scholar, communicator, professional, and collaborator. A practice audit is beneficial to an individual physician; furthermore, publication of the audit results could be beneficial for many others such as health care providers, patients, and other stakeholders in a health care system. The problem is that practice audits often begin without a clear plan. The important steps in planning and carrying out a practice audit can be captured by thinking about how a research publication evolves. Thus, a good researcher is a good practice auditor. This paper reviews the author's experience and provides examples and directions of the process of practice-audit-publish.

Large gamma-ray detector arrays and electromagnetic separators

NASA Astrophysics Data System (ADS)

Lee, I.-Yang

2013-12-01

The use of large gamma-ray detector arrays with electromagnetic separators is a powerful combination. Various types of gamma-ray detectors have been used; some provide high detector efficiency such as scintillation detector array, others use Ge detectors for good energy resolution, and recently developed Ge energy tracking arrays gives both high peak-to-background ratio and position resolution. Similarly, different types of separators were used to optimize the performance under different experimental requirements and conditions. For example, gas-filled separators were used in heavy element studies for their large efficiency and beam rejection factor. Vacuum separators with good isotope resolution were used in transfer and fragmentation reactions for the study of nuclei far from stability. This paper presents results from recent experiments using gamma-ray detector arrays in combination with electromagnetic separators, and discusses the physics opportunities provided by these instruments. In particular, we review the performance of the instruments currently in use, and discuss the requirements of instruments for future radioactive beam accelerator facilities.

Practice-audit-publish: A practice reflection

PubMed Central

Ferrari, Robert

2016-01-01

Practice audits are useful opportunities to improve practice efficiency and effectiveness, reduce clinical errors, demonstrate quality care to stakeholders, promote high standards of practice, lower the risk of liability, and foster practice change. However, a benefit that is usually overlooked is the possibility of publication of the results of a practice audit. Publication (research) has a number of benefits for the clinician, including skill development as a scholar, communicator, professional, and collaborator. A practice audit is beneficial to an individual physician; furthermore, publication of the audit results could be beneficial for many others such as health care providers, patients, and other stakeholders in a health care system. The problem is that practice audits often begin without a clear plan. The important steps in planning and carrying out a practice audit can be captured by thinking about how a research publication evolves. Thus, a good researcher is a good practice auditor. This paper reviews the author’s experience and provides examples and directions of the process of practice-audit-publish. PMID:28149662

Good governance for nutrition in the Philippines: elements, experiences, and lessons learned.

PubMed

Solon, Florentino S

2006-12-01

Malnutrition is a multifactorial problem that needs a multisectoral solution. This article reviews the role of good governance in nutrition programs, citing the Philippines as an example. In the Philippines, these efforts are reflected in the partnership between the public and private sectors in the establishment of the country's capability in research, policy-making, and program implementation. The establishment of the different public institutions engaged in research and policy-making is discussed, highlighting the role of political will through legislation. The evolving tasks of the nutrition program are discussed by citing the tasks in two eras. In the 1970s, the challenges were limited national nutrition data, man-power, tools, and health infrastructure. The public and private institutions were able to respond by legislating national nutrition surveys and dedicated nutrition workers in each village. The challenges in the current era are improved implementation of health programs, given the devolution of health services, and the gathering of an evidence base to further strengthen and refine the strategies of supplementation, fortification, breastfeeding, and food security. In responding to these challenges, multisectoral solutions and collaboration are critical in providing an evidence base to formulate policy. The role of the private sector, with the Nutrition Center of the Philippines used as an example, is that of a supportive and collaborative partner in good governance. Finally, the lessons learned from the past decades of implementing a national nutrition program, given changes in political and economic circumstances, are summarized.

Conflict and coordination in the provision of public goods: a conceptual analysis of continuous and step-level games.

PubMed

Abele, Susanne; Stasser, Garold; Chartier, Christopher

2010-11-01

Conflicts between individual and collective interests are ubiquitous in social life. Experimental studies have investigated the resolution of such conflicts using public goods games with either continuous or step-level payoff functions. Game theory and social interdependence theory identify consequential differences between these two types of games. Continuous function games are prime examples of social dilemmas because they always contain a conflict between individual and collective interests, whereas step-level games can be construed as social coordination games. Step-level games often provide opportunities for coordinated solutions that benefit both the collective and the individuals. For this and other reasons, the authors conclude that one cannot safely generalize results obtained from step-level to continuous-form games (or vice versa). Finally, the authors identify specific characteristics of the payoff function in public goods games that conceptually mark the transition from a pure dilemma to a coordination problem nested within a dilemma.

Developing a policy for paediatric biobanks: principles for good practice

PubMed Central

Hens, Kristien; Van El, Carla E; Borry, Pascal; Cambon-Thomsen, Anne; Cornel, Martina C; Forzano, Francesca; Lucassen, Anneke; Patch, Christine; Tranebjaerg, Lisbeth; Vermeulen, Eric; Salvaterra, Elena; Tibben, Aad; Dierickx, Kris

2013-01-01

The participation of minors in biobank research can offer great benefits for science and health care. However, as minors are a vulnerable population they are also in need of adequate protective measures when they are enrolled in research. Research using biobanked biological samples from children poses additional ethical issues to those raised by research using adult biobanks. For example, small children have only limited capacity, if any, to understand the meaning and implications of the research and to give a documented agreement to it. Older minors are gradually acquiring this capacity. We describe principles for good practice related to the inclusion of minors in biobank research, focusing on issues related to benefits and subsidiarity, consent, proportionality and return of results. Some of these issues are currently heavily debated, and we conclude by providing principles for good practice for policy makers of biobanks, researchers and anyone involved in dealing with stored tissue samples from children. Actual implementation of the principles will vary according to different jurisdictions. PMID:22713814

Methods for Calibration of Prout-Tompkins Kinetics Parameters Using EZM Iteration and GLO

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wemhoff, A P; Burnham, A K; de Supinski, B

2006-11-07

This document contains information regarding the standard procedures used to calibrate chemical kinetics parameters for the extended Prout-Tompkins model to match experimental data. Two methods for calibration are mentioned: EZM calibration and GLO calibration. EZM calibration matches kinetics parameters to three data points, while GLO calibration slightly adjusts kinetic parameters to match multiple points. Information is provided regarding the theoretical approach and application procedure for both of these calibration algorithms. It is recommended that for the calibration process, the user begin with EZM calibration to provide a good estimate, and then fine-tune the parameters using GLO. Two examples have beenmore » provided to guide the reader through a general calibrating process.« less

Revision Cycles for Economics Textbooks: An Application of the Theory of Durable Goods Monopoly

ERIC Educational Resources Information Center

Li, Xin

2011-01-01

In this dissertation, I study economics textbook markets as an example of durable goods monopoly. Textbooks are protected by copyrights, and from a student's point of view, different textbooks are not good substitutes because students wish to use the textbook adopted by their instructors. Therefore sellers have market power. Textbooks can be…

Rapid Harmonic Analysis of Piezoelectric MEMS Resonators.

PubMed

Puder, Jonathan M; Pulskamp, Jeffrey S; Rudy, Ryan Q; Cassella, Cristian; Rinaldi, Matteo; Chen, Guofeng; Bhave, Sunil A; Polcawich, Ronald G

2018-06-01

This paper reports on a novel simulation method combining the speed of analytical evaluation with the accuracy of finite-element analysis (FEA). This method is known as the rapid analytical-FEA technique (RAFT). The ability of the RAFT to accurately predict frequency response orders of magnitude faster than conventional simulation methods while providing deeper insights into device design not possible with other types of analysis is detailed. Simulation results from the RAFT across wide bandwidths are compared to measured results of resonators fabricated with various materials, frequencies, and topologies with good agreement. These include resonators targeting beam extension, disk flexure, and Lamé beam modes. An example scaling analysis is presented and other applications enabled are discussed as well. The supplemental material includes example code for implementation in ANSYS, although any commonly employed FEA package may be used.

Processing of Advanced Ceramics Which Have Potential for Use in Gas Turbine Aero Engines

DTIC Science & Technology

1989-02-01

reaons . Details on the availability of these publications may be obtained from: Graphics Section, National Research Council Canada, National...have been produced by hot isostatic pressing (HIP’ing) have good potential to be used as hot section components in gas turbine aero engines. This...Alumina, for example, maintains good corrosion resistance, good stiffness, and good strength at high temperatures, but exhibits very poor thermal shock

Procedural instructions, principles, and examples: how to structure instructions for procedural tasks to enhance performance, learning, and transfer.

PubMed

Eiriksdottir, Elsa; Catrambone, Richard

2011-12-01

The goal of this article is to investigate how instructions can be constructed to enhance performance and learning of procedural tasks. Important determinants of the effectiveness of instructions are type of instructions (procedural information, principles, and examples) and pedagogical goal (initial performance, learning, and transfer). Procedural instructions describe how to complete tasks in a stepwise manner, principles describe rules governing the tasks, and examples demonstrate how instances of the task are carried out. The authors review the research literature associated with each type of instruction to identify factors determining effectiveness for different pedagogical goals. The results suggest a trade-off between usability and learnability. Specific instructions help initial performance, whereas more general instructions, requiring problem solving, help learning and transfer. Learning from instructions takes cognitive effort, and research suggests that learners typically opt for low effort. However, it is possible to meet both goals of good initial performance and learning with methods such as fading and by combining different types of instructions. How instructions are constructed influences their effectiveness for the goals of good initial performance, learning, and transfer, and it is therefore important for researchers and practitioners alike to define the pedagogical goal of instructions. If the goal is good initial performance, then instructions should highly resemble the task at hand (e.g., in the form of detailed procedural instructions and examples), but if the goal is good learning and transfer, then instructions should be more abstract, inducing learners to expend the necessary cognitive effort for learning.

The European Political Environment and NATO Maritime Strategy: The Future Role of Naval Forces in the Forward Defense of Western Europe. Volume 2.

DTIC Science & Technology

1985-07-10

defence of Malaysia 1964-66 is an example. The actions of Alliance members may be altruistic, but certainly can help to reduce the risks of local...have favoured the Silent Service tradition and had resisted the efforts of the chief censor to provide facilities for newspaper correspondents to visit... Malaysia , New Zealand, Singapore and the United Kingdom is such a one. There are good reasons why as many members as possible should maintain the

Industrial uses and applications of ionic liquids

NASA Astrophysics Data System (ADS)

Gutowski, Keith E.

2018-02-01

Ionic liquids are salts that melt at low temperatures (usually defined as less than 100 °C) and have a number of interesting properties that make them useful for industrial applications. Typical ionic liquid properties include high thermal stabilities, negligible vapor pressures, wide liquidus ranges, broad electrochemical windows, and unique solvation properties. Furthermore, the potential combinations of cations and anions provide nearly unlimited chemical tunability. This article will describe the diverse industrial uses of ionic liquids and how their unique properties are leveraged, with examples ranging from chemical processing to consumer packaged goods.

Friedel-Crafts Acylation with Amides

PubMed Central

Raja, Erum K.; DeSchepper, Daniel J.; Nilsson Lill, Sten O.; Klumpp, Douglas A.

2012-01-01

Friedel-Crafts acylation has been known since the 1870s and it is an important organic synthetic reaction leading to aromatic ketone products. Friedel-Crafts acylation is usually done with carboxylic acid chlorides or anhydrides while amides are generally not useful substrates in these reactions. Despite being the least reactive carboxylic acid derivative, we have found a series of amides capable of providing aromatic ketones in good yields (55–96%, 17 examples). We propose a mechanism involving diminished C-N resonance through superelectrophilic activation and subsequent cleavage to acyl cations. PMID:22690740

Conjugated polymers and their use in optoelectronic devices

DOEpatents

Marks, Tobin J.; Guo, Xugang; Zhou, Nanjia; Chang, Robert P. H.; Drees, Martin; Facchetti, Antonio

2016-10-18

The present invention relates to certain polymeric compounds and their use as organic semiconductors in organic and hybrid optical, optoelectronic, and/or electronic devices such as photovoltaic cells, light emitting diodes, light emitting transistors, and field effect transistors. The present compounds can provide improved device performance, for example, as measured by power conversion efficiency, fill factor, open circuit voltage, field-effect mobility, on/off current ratios, and/or air stability when used in photovoltaic cells or transistors. The present compounds can have good solubility in common solvents enabling device fabrication via solution processes.

Dimming LEDs with Phase-Cut Dimmers. The Specifier's Process for Maximizing Success

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miller, N. J.; Poplawski, M. E.

2013-10-01

DOE GATEWAY program report reviewing how phase-cut dimmers work, how LEDs differ from the incandescent lamps these dimmers were originally designed to control, and how those differences can lead to complications when attempting to dim LEDs. Providing both general guidance and step-by-step procedures for designing phase-controlled LED dimming on both new and existing projects—as well as real-world examples of how to use those procedures—the report aims to reduce the chance of experiencing compatibility-related problems and, if possible, ensure good dimming performance.

Airy beams on two dimensional materials

NASA Astrophysics Data System (ADS)

Imran, Muhammad; Li, Rujiang; Jiang, Yuyu; Lin, Xiao; Zheng, Bin; Dehdashti, Shahram; Xu, Zhiwei; Wang, Huaping

2018-05-01

We propose that quasi-transverse-magnetic (quasi-TM) Airy beams can be supported on two dimensional (2D) materials. By taking graphene as a typical example, the solution of quasi-TM Airy beams is studied under the paraxial approximation. The analytical field intensity in a bilayer graphene-based planar plasmonic waveguide is confirmed by the simulation results. Due to the tunability of the chemical potential of graphene, the self-accelerating behavior of the quasi-TM Airy beam can be steered effectively. 2D materials thus provide a good platform to investigate the propagation of Airy beams.

Silylene-diethynyl-arylene polymers having liquid crystalline properties

DOEpatents

Barton, Thomas J.; Ding, Yiwei

1993-09-07

The present invention provides linear organosilicon polymers including diethynyl-(substituted)arylene units, and a process for their preparation. These novel polymers possess useful properties including electrical conductivity, liquid crystallinity, and/or photoluminescence. These polymers possess good solubility in organic solvents. A preferred example is produced according to the following reaction scheme. ##STR1## These polymers can be solvent-cast to yield excellent films and can also be pulled into fibers from concentrated solutions. All possess substantial crystallinity as revealed by DSC analysis and observation through a polarizing microscope, and possess liquid crystalline properties.

Saying Good-by: An Example of Using a Good-by Technique and Concomitant Psychodrama in the Resolving of Family Grief.

ERIC Educational Resources Information Center

Kaminski, Robert C.

A structured technique for saying "good-bye," or terminating a relationship, an important aspect of the therapeutic relationship, is presented. It consists of three distinct phases that are all dynamically interrelated, and can also be structured into separation caused by death. The technique is described in terms of three specific areas…

Leading by Example in a Public Goods Experiment with Heterogeneity and Incomplete Information

ERIC Educational Resources Information Center

Levati, M. Vittoria; Sutter, Matthias; van der Heijden, Eline

2007-01-01

We study the effects of leadership on the private provision of a public good when group members are heterogeneously endowed. Leadership is implemented as a sequential public goods game where one group member contributes first and all the others follow. Our results show that the presence of a leader increases average contribution levels but less so…

An outline of tectonic, igneous, and metamorphic events in the Goshute-Toano Range between Silver Zone Pass and White Horse Pass, Elko County, Nevada; a history of superposed contractional and extensional deformation

USGS Publications Warehouse

Ketner, Keith Brindley; Day, Warren C.; Elrick, Maya; Vaag, Myra K.; Zimmerman, Robert A.; Snee, Lawrence W.; Saltus, Richard W.; Repetski, John E.; Wardlaw, Bruce R.; Taylor, Michael E.; Harris, Anita G.

1998-01-01

Seven kinds of fault-bounded tracts are described. One of the tracts provides a good example of Mesozoic contractional folding and faulting; six exemplify various aspects of Miocene extensional faulting. Massive landslide deposits resulting from Tertiary faulting are described. Mesozoic intrusive rocks and extensive exposures of Miocene volcanic rocks are described and dated. The age ranges of stratigraphic units were based on numerous conodont collections, and ages of igneous rocks were determined by argon/argon and fission-track methods. The geologic complexity of the Goshute-Toano Range provides opportunities for many additional productive structural studies.

The 2.5-diacyl-1,4-dimethylbenzenes: Examples of bisphotoenol equivalents

NASA Technical Reports Server (NTRS)

Meador, Michael A.

1987-01-01

The photochemistry of 2,5-dibenzoyl(DBX)-and 2,5-diacetyl-1,4-dimethylbenzene (DAX) has been investigated. Both compounds readily undergo photoenolization similar to 0-alkylphenyl ketones. However, unlike 0-alkylphenyl ketones DAX and DBX are each capable of undergoing two tandem photoenolizations. Photoenols derived from o-alkylphenyl ketones have been successfully trapped with Diels-Alder dienophiles to provide a convenient synthesis of substituted tetralins. Similarly, Diels-Alder trapping of DBX photoenils afforded substituted tetra- and octahydro anthracenes. Further mainpulation of these photadducts provided the corresponding anthracenes in good yield. The photochemistry of DAX and DBX will be discussed, in particular their use in the synthesis of substituted anthracenes.

Low-Coherence Reflectometry for Refractive Index Measurements of Cells in Micro-Capillaries.

PubMed

Carpignano, Francesca; Rigamonti, Giulia; Mazzini, Giuliano; Merlo, Sabina

2016-10-11

The refractive index of cells provides insights into their composition, organization and function. Moreover, a good knowledge of the cell refractive index would allow an improvement of optical cytometric and diagnostic systems. Although interferometric techniques undoubtedly represent a good solution for quantifying optical path variation, obtaining the refractive index of a population of cells non-invasively remains challenging because of the variability in the geometrical thickness of the sample. In this paper, we demonstrate the use of infrared low-coherence reflectometry for non-invasively quantifying the average refractive index of cell populations gently confined in rectangular glass micro-capillaries. A suspension of human red blood cells in plasma is tested as a reference. As a use example, we apply this technique to estimate the average refractive index of cell populations belonging to epithelial and hematological families.

Low-Coherence Reflectometry for Refractive Index Measurements of Cells in Micro-Capillaries

PubMed Central

Carpignano, Francesca; Rigamonti, Giulia; Mazzini, Giuliano; Merlo, Sabina

2016-01-01

The refractive index of cells provides insights into their composition, organization and function. Moreover, a good knowledge of the cell refractive index would allow an improvement of optical cytometric and diagnostic systems. Although interferometric techniques undoubtedly represent a good solution for quantifying optical path variation, obtaining the refractive index of a population of cells non-invasively remains challenging because of the variability in the geometrical thickness of the sample. In this paper, we demonstrate the use of infrared low-coherence reflectometry for non-invasively quantifying the average refractive index of cell populations gently confined in rectangular glass micro-capillaries. A suspension of human red blood cells in plasma is tested as a reference. As a use example, we apply this technique to estimate the average refractive index of cell populations belonging to epithelial and hematological families. PMID:27727172

Cooperation, Trust, and Antagonism: How Public Goods Are Promoted.

PubMed

Parks, Craig D; Joireman, Jeff; Van Lange, Paul A M

2013-12-01

One of the most continually vexing problems in society is the variability with which citizens support endeavors that are designed to help a great number of people. In this article, we examine the twin roles of cooperative and antagonistic behavior in this variability. We find that each plays an important role, though their contributions are, understandably, at odds. It is this opposition that produces seeming unpredictability in citizen response to collective need. In fact, we suggest that careful consideration of the research allows one to often predict when efforts to provide a collectively beneficial good will succeed and when they will fail. To understand the dynamics of participation in response to collective need, it is necessary to distinguish between the primary types of need situations. A public good is an entity that relies in whole or in part on contributions to be provided. Examples of public goods are charities and public broadcasting. Public goods require that citizens experience a short-term loss (of their contribution) in order to realize a long-term gain (of the good). However, because everyone can use the good once it is provided, there is also an incentive to not contribute, let others give, and then take advantage of their efforts. This state of affairs introduces a conflict between doing what is best for oneself and what is best for the group. In a public goods situation, cooperation and antagonism impact how one resolves this conflict. The other major type of need situation is a common-pool resource problem. Here, a good is fully provided at the outset, and citizens may sample from it. The resource is usually, but not necessarily, partially replenished. Examples of replenished resources are drinking water and trees; examples of resources that are functionally not replenished are oil and minerals. Common-pool resources allow citizens to experience a short-term gain (by getting what they want in the early life of the resource) but also present the possibility of a long-term loss (if the resource dries up). As with public goods, there is thus a conflict between, on the one hand, acting in one's best interest and taking as much as one wants all the time and, on the other, acting for the good of the group, which requires taking a lesser amount so that the replenishment rate can keep up with the rate of use. As with public goods, both cooperation and antagonism affect this decision. With these situations in mind, we can now dig deeply into the dynamics of both cooperation and antagonism. Cooperation is one of the most heavily studied aspects of human behavior, yet despite this attention, there is much that is not understood about it, including its fundamental base. There are a number of different perspectives on the base. Interdependence theory argues that cooperation is driven by how one interprets the subjective value of the outcomes that will result from various combinations of behaviors. A person who sees a potential result of "50 to you, 50 to me" as "We both would do well" is more likely to cooperate than the person who sees it as "I would not outgain the other person." Self-control theory suggests that cooperation is a function of how well a person can resist the impulse to benefit now and delay gratification. Evolutionary theory takes many forms but revolves around the extent to which cooperation is adaptive. Finally, the appropriateness framework takes a cognitive approach and assumes that cooperation is determined by a combination of social-cognitive (interpretation of self and the situation) and decision-heuristic factors. We propose that it is possible to integrate across these approaches and understand cooperation as a behavior that is influenced by all of these factors as well as other dynamics, such as cultural mores and personality traits. Antagonism, as it relates to the collective welfare, is a phenomenon with a lesser history but one that is clearly influential. A number of facets of antagonism are relevant. Power, and its abuse, is a major factor, and a specific application to collective goods is the notion of a "gatekeeper," or a person who can completely determine whether a public good exists or a common-pool resource can be used. Gatekeepers tend to demand ample compensation from others in order for the good or resource to go forward. If this demand is resisted, as it often is, the end result is that the good is not provided or the resource not accessed. Another facet is the desire to see an out-group be harmed. Sometimes, this motivation is so strong that people will deny themselves a good outcome in order to see the harm occur. Why someone would want to see an out-group be harmed is debatable, but it may be attributable to a desire to be seen as a winner, or it may be a strategy designed to produce a net benefit for one's in-group. Emotions also play a role, with people tending to assume that out-group members have just basic emotions such as happiness and sadness and not secondary emotions such as guilt and shame. Because out-group members are emotionally simple, it is seen as acceptable to treat them badly. Complicating matters even further is that antagonism can sometimes be seen against in-group members who deviate, in either direction, from the group norm and against individuals who are behaving in a clearly selfless manner, like volunteers. A number of approaches have been proposed to the resolution of public goods problems. Structural solutions act to alter the basic dynamic of the dilemma by means of interventions such as rewards for cooperation, punishment for noncooperation, and selection of a single group member to chart a course of action for everyone. Third-party solutions involve the bringing in of an external agent to help determine how group members should behave. These agents may be more passive and merely suggest solutions, or they may be more active and dictate how decisions will be made, what decision will be made, or both. Finally, psychological solutions involve changing how people view the situation. We finish by discussing how policy makers can improve the chances of a publicly valuable good being supported. We particularly emphasize creation of a felt connection with future generations; clear demonstration of immediate and concrete consequences as a result of failure to provide the good; instillation of a sense of community; and isolation of the good from other, related issues. We also take up the general problem of distrust of those who establish policy and discuss some methods for helping minimize distrust. © The Author(s) 2013.

Green marketing, renewables, and free riders: increasing customer demand for a public good

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wiser, R.; Pickle, S.

1997-09-01

Retail electricity competition will allow customers to select their own power suppliers and some customers will make purchase decisions based, in part, on their concern for the environment. Green power marketing targets these customers under the assumption that they will pay a premium for ``green`` energy products such as renewable power generation. But renewable energy is not a traditional product because it supplies public goods; for example, a customer supporting renewable energy is unable to capture the environmental benefits that their investment provides to non-participating customers. As with all public goods, there is a risk that few customers will purchasemore » ``green`` power and that many will instead ``free ride`` on others` participation. By free riding, an individual is able to enjoy the benefits of the public good while avoiding payment. This report reviews current green power marketing activities in the electric industry, introduces the extensive academic literature on public goods, free riders, and collective action problems, and explores in detail the implications of this literature for the green marketing of renewable energy. Specifically, the authors highlight the implications of the public goods literature for green power product design and marketing communications strategies. They emphasize four mechanisms that marketers can use to increase customer demand for renewable energy. Though the public goods literature can also contribute insights into the potential rationale for renewable energy policies, they leave most of these implications for future work (see Appendix A for a possible research agenda).« less

Research on Design Information Management System for Leather Goods

NASA Astrophysics Data System (ADS)

Lu, Lei; Peng, Wen-li

The idea of setting up a design information management system of leather goods was put forward to solve the problems existed in current information management of leather goods. Working principles of the design information management system for leather goods were analyzed in detail. Firstly, the acquiring approach of design information of leather goods was introduced. Secondly, the processing methods of design information were introduced. Thirdly, the management of design information in database was studied. Finally, the application of the system was discussed by taking the shoes products as an example.

Optimal Interventions in Host-Nation Health Systems During Counterinsurgency Operations

DTIC Science & Technology

2014-12-12

suggest. Finally, stability operations within COIN should consider childhood malnutrition rates and the access to improved water sources as good...consider childhood malnutrition rates and the access to improved water sources as good examples of potential measures of effectiveness (MOEs) that may...

Development of a cost-effectiveness analysis of leafy green marketing agreement irrigation water provisions.

PubMed

Jensen, Helen H; Pouliot, Sébastien; Wang, Tong; Jay-Russell, Michele T

2014-06-01

An analysis of the effectiveness of meeting the irrigation water provisions of the Leafy Green Marketing Agreement (LGMA) relative to its costs provides an approach to evaluating the cost-effectiveness of good agricultural practices that uses available data. A case example for lettuce is used to evaluate data requirements and provide a methodological example to determine the cost-effectiveness of the LGMA water quality provision. Both cost and field data on pathogen or indicator bacterial levels are difficult and expensive to obtain prospectively. Therefore, methods to use existing field and experimental data are required. Based on data from current literature and experimental studies, we calculate a cost-efficiency ratio that expresses the reduction in E. coli concentration per dollar expenditure on testing of irrigation water. With appropriate data, the same type of analysis can be extended to soil amendments and other practices and to evaluation of public benefits of practices used in production. Careful use of existing and experimental data can lead to evaluation of an expanded set of practices.

"The Errors Were the Results of Errors": Promoting Good Writing by Bad Example

ERIC Educational Resources Information Center

Korsunsky, Boris

2010-01-01

We learn best by example--this adage is probably as old as teaching itself. In my own classroom, I have found that very often the students learn best from the "negative" examples. Perhaps, this shouldn't come as a surprise at all. After all, we don't react strongly to the norm--but an obvious deviation from the norm may attract our attention and…

Recovery-oriented care in a secure mental health setting: "striving for a good life".

PubMed

McKenna, Brian; Furness, Trentham; Dhital, Deepa; Park, Malcolm; Connally, Fiona

2014-01-01

Recovery-oriented care acknowledges the unique journey of the consumer to regain control of his or her life in order to live a good life. Recovery has become a dominant policy-directed model of mental health service delivery. Even services that have traditionally been institutional and custodial have been challenged to embrace a recovery-oriented model. The aim of this qualitative study was to provide a description of service delivery in a secure in-patient mental health service, which has developed a self-professed recovery-oriented model of service delivery. An in-depth case study of the secure in-patient service using an exploratory research design was undertaken to meet the aim of this study. Qualitative data was gathered from interviews with consumers and staff (n = 15) and a focus group with carers (n = 5). Data were analyzed using a content analysis approach. Ethical approval for the study was obtained. The stakeholders readily described the secure service within recovery domains. They described a common vision; ways to promote hope and autonomy; examples of collaborative partnership which enhanced the goal of community integration; a focus on strength-based, holistic care; and the management of risk by taking calculated risks. Discrepancies in the perceptions of stakeholders were determined. This case study research provides a demonstrable example of recovery-in-action in one secure mental health service in Australia. It is intended to assist mental health services and clinicians seeking guidance in developing strategies for building and maintaining partnerships with consumers and carers in order for secure services to become truly recovery-oriented.

Bayesian historical earthquake relocation: an example from the 1909 Taipei earthquake

USGS Publications Warehouse

Minson, Sarah E.; Lee, William H.K.

2014-01-01

Locating earthquakes from the beginning of the modern instrumental period is complicated by the fact that there are few good-quality seismograms and what traveltimes do exist may be corrupted by both large phase-pick errors and clock errors. Here, we outline a Bayesian approach to simultaneous inference of not only the hypocentre location but also the clock errors at each station and the origin time of the earthquake. This methodology improves the solution for the source location and also provides an uncertainty analysis on all of the parameters included in the inversion. As an example, we applied this Bayesian approach to the well-studied 1909 Mw 7 Taipei earthquake. While our epicentre location and origin time for the 1909 Taipei earthquake are consistent with earlier studies, our focal depth is significantly shallower suggesting a higher seismic hazard to the populous Taipei metropolitan area than previously supposed.

Sensitivity Analysis of earth and environmental models: a systematic review to guide scientific advancement

NASA Astrophysics Data System (ADS)

Wagener, Thorsten; Pianosi, Francesca

2016-04-01

Sensitivity Analysis (SA) investigates how the variation in the output of a numerical model can be attributed to variations of its input factors. SA is increasingly being used in earth and environmental modelling for a variety of purposes, including uncertainty assessment, model calibration and diagnostic evaluation, dominant control analysis and robust decision-making. Here we provide some practical advice regarding best practice in SA and discuss important open questions based on a detailed recent review of the existing body of work in SA. Open questions relate to the consideration of input factor interactions, methods for factor mapping and the formal inclusion of discrete factors in SA (for example for model structure comparison). We will analyse these questions using relevant examples and discuss possible ways forward. We aim at stimulating the discussion within the community of SA developers and users regarding the setting of good practices and on defining priorities for future research.

Holographic 3D imaging through diffuse media by compressive sampling of the mutual intensity

NASA Astrophysics Data System (ADS)

Falldorf, Claas; Klein, Thorsten; Agour, Mostafa; Bergmann, Ralf B.

2017-05-01

We present a method for holographic imaging through a volume scattering material, which is based on selfreference and light with good spatial but limited temporal coherence. In contrast to existing techniques, we do not require a separate reference wave, thus our approach provides great advantages towards the flexibility of the measurement system. The main applications are remote sensing and investigation of moving objects through gaseous streams, bubbles or foggy water for example. Furthermore, due to the common path nature, the system is also insensitive to mechanical disturbances. The measurement result is a complex amplitude which is comparable to a phase shifted digital hologramm and therefore allows 3D imaging, numerical refocusing and quantitative phase contrast imaging. As an example of application, we present measurements of the quantitative phase contrast of the epidermis of an onion through a volume scattering material.

31 CFR 560.414 - Reexportation of certain U.S.-origin goods exported prior to May 7, 1995.

Code of Federal Regulations, 2013 CFR

2013-07-01

... reexportation of the U.S.-origin goods or technology to Iran or the Government of Iran was not subject to... Iran or the Government of Iran. For example, items which meet the conditions of paragraph (a) may...

31 CFR 560.414 - Reexportation of certain U.S.-origin goods exported prior to May 7, 1995.

Code of Federal Regulations, 2014 CFR

2014-07-01

... reexportation of the U.S.-origin goods or technology to Iran or the Government of Iran was not subject to... Iran or the Government of Iran. For example, items which meet the conditions of paragraph (a) may...

31 CFR 560.414 - Reexportation of certain U.S.-origin goods exported prior to May 7, 1995.

Code of Federal Regulations, 2012 CFR

2012-07-01

... goods or technology to Iran or the Government of Iran was not subject to reexport (as opposed to export... agencies of the U.S. Government for reexportation to Iran or the Government of Iran. For example, items...

31 CFR 560.414 - Reexportation of certain U.S.-origin goods exported prior to May 7, 1995.

Code of Federal Regulations, 2011 CFR

2011-07-01

... goods or technology to Iran or the Government of Iran was not subject to reexport (as opposed to export... agencies of the U.S. Government for reexportation to Iran or the Government of Iran. For example, items...

Representation of Sound Categories in Auditory Cortical Maps

ERIC Educational Resources Information Center

Guenther, Frank H.; Nieto-Castanon, Alfonso; Ghosh, Satrajit S.; Tourville, Jason A.

2004-01-01

Functional magnetic resonance imaging (fMRI) was used to investigate the representation of sound categories in human auditory cortex. Experiment 1 investigated the representation of prototypical (good) and nonprototypical (bad) examples of a vowel sound. Listening to prototypical examples of a vowel resulted in less auditory cortical activation…

Sex Stereotypes as Natural Language Categories.

ERIC Educational Resources Information Center

Safarjan, Paula Tinder; De Lisi, Richard

Results of research to identify words which are perceived to characterize male and female traits are reported. Ninety-six undergraduate students, 48 male and 48 female, rated 210 adjectives on a five-point scale ranging from "very good example" to "very poor example." Researchers then categorized results according to core (best category…

The Evaluation and Selection of Adequate Causal Models: A Compensatory Education Example.

ERIC Educational Resources Information Center

Tanaka, Jeffrey S.

1982-01-01

Implications of model evaluation (using traditional chi square goodness of fit statistics, incremental fit indices for covariance structure models, and latent variable coefficients of determination) on substantive conclusions are illustrated with an example examining the effects of participation in a compensatory education program on posttreatment…

26 CFR 1.6664-4 - Reasonable cause and good faith exception to section 6662 penalties.

Code of Federal Regulations, 2011 CFR

2011-04-01

... claimed. Example 3. E, an individual, worked for Company X doing odd jobs and filling in for other... legal justification. (3) Minimum requirements not dispositive. Satisfaction of the minimum requirements... example, depending on the circumstances, satisfaction of the minimum requirements may not be dispositive...

The design, deployment, and testing of kriging models in GEOframe with SIK-0.9.8

NASA Astrophysics Data System (ADS)

Bancheri, Marialaura; Serafin, Francesco; Bottazzi, Michele; Abera, Wuletawu; Formetta, Giuseppe; Rigon, Riccardo

2018-06-01

This work presents a software package for the interpolation of climatological variables, such as temperature and precipitation, using kriging techniques. The purposes of the paper are (1) to present a geostatistical software that is easy to use and easy to plug in to a hydrological model; (2) to provide a practical example of an accurately designed software from the perspective of reproducible research; and (3) to demonstrate the goodness of the results of the software and so have a reliable alternative to other, more traditional tools. A total of 11 types of theoretical semivariograms and four types of kriging were implemented and gathered into Object Modeling System-compliant components. The package provides real-time optimization for semivariogram and kriging parameters. The software was tested using a year's worth of hourly temperature readings and a rain storm event (11 h) recorded in 2008 and retrieved from 97 meteorological stations in the Isarco River basin, Italy. For both the variables, good interpolation results were obtained and then compared to the results from the R package gstat.

Structure-Guided Discovery of Novel, Potent, and Orally Bioavailable Inhibitors of Lipoprotein-Associated Phospholipase A2.

PubMed

Liu, Qiufeng; Huang, Fubao; Yuan, Xiaojing; Wang, Kai; Zou, Yi; Shen, Jianhua; Xu, Yechun

2017-12-28

Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a promising therapeutic target for atherosclerosis, Alzheimer's disease, and diabetic macular edema. Here we report the identification of novel sulfonamide scaffold Lp-PLA2 inhibitors derived from a relatively weak fragment. Similarity searching on this fragment followed by molecular docking leads to the discovery of a micromolar inhibitor with a 300-fold potency improvement. Subsequently, by the application of a structure-guided design strategy, a successful hit-to-lead optimization was achieved and a number of Lp-PLA2 inhibitors with single-digit nanomolar potency were obtained. After preliminary evaluation of the properties of drug-likeness in vitro and in vivo, compound 37 stands out from this congeneric series of inhibitors for good inhibitory activity and favorable oral bioavailability in male Sprague-Dawley rats, providing a quality candidate for further development. The present study thus clearly demonstrates the power and advantage of integrally employing fragment screening, crystal structures determination, virtual screening, and medicinal chemistry in an efficient lead discovery project, providing a good example for structure-based drug design.

Modeling fibrous biological tissues with a general invariant that excludes compressed fibers

NASA Astrophysics Data System (ADS)

Li, Kewei; Ogden, Ray W.; Holzapfel, Gerhard A.

2018-01-01

Dispersed collagen fibers in fibrous soft biological tissues have a significant effect on the overall mechanical behavior of the tissues. Constitutive modeling of the detailed structure obtained by using advanced imaging modalities has been investigated extensively in the last decade. In particular, our group has previously proposed a fiber dispersion model based on a generalized structure tensor. However, the fiber tension-compression switch described in that study is unable to exclude compressed fibers within a dispersion and the model requires modification so as to avoid some unphysical effects. In a recent paper we have proposed a method which avoids such problems, but in this present study we introduce an alternative approach by using a new general invariant that only depends on the fibers under tension so that compressed fibers within a dispersion do not contribute to the strain-energy function. We then provide expressions for the associated Cauchy stress and elasticity tensors in a decoupled form. We have also implemented the proposed model in a finite element analysis program and illustrated the implementation with three representative examples: simple tension and compression, simple shear, and unconfined compression on articular cartilage. We have obtained very good agreement with the analytical solutions that are available for the first two examples. The third example shows the efficacy of the fibrous tissue model in a larger scale simulation. For comparison we also provide results for the three examples with the compressed fibers included, and the results are completely different. If the distribution of collagen fibers is such that it is appropriate to exclude compressed fibers then such a model should be adopted.

Wire Detection Algorithms for Navigation

NASA Technical Reports Server (NTRS)

Kasturi, Rangachar; Camps, Octavia I.

2002-01-01

In this research we addressed the problem of obstacle detection for low altitude rotorcraft flight. In particular, the problem of detecting thin wires in the presence of image clutter and noise was studied. Wires present a serious hazard to rotorcrafts. Since they are very thin, their detection early enough so that the pilot has enough time to take evasive action is difficult, as their images can be less than one or two pixels wide. Two approaches were explored for this purpose. The first approach involved a technique for sub-pixel edge detection and subsequent post processing, in order to reduce the false alarms. After reviewing the line detection literature, an algorithm for sub-pixel edge detection proposed by Steger was identified as having good potential to solve the considered task. The algorithm was tested using a set of images synthetically generated by combining real outdoor images with computer generated wire images. The performance of the algorithm was evaluated both, at the pixel and the wire levels. It was observed that the algorithm performs well, provided that the wires are not too thin (or distant) and that some post processing is performed to remove false alarms due to clutter. The second approach involved the use of an example-based learning scheme namely, Support Vector Machines. The purpose of this approach was to explore the feasibility of an example-based learning based approach for the task of detecting wires from their images. Support Vector Machines (SVMs) have emerged as a promising pattern classification tool and have been used in various applications. It was found that this approach is not suitable for very thin wires and of course, not suitable at all for sub-pixel thick wires. High dimensionality of the data as such does not present a major problem for SVMs. However it is desirable to have a large number of training examples especially for high dimensional data. The main difficulty in using SVMs (or any other example-based learning method) is the need for a very good set of positive and negative examples since the performance depends on the quality of the training set.

Analysis of the Salvation Army World Service Offices Disaster Relief Capabilities

DTIC Science & Technology

2017-03-01

AOR based primarily on their financial revenues, since revenue is a prerequisite enabling mechanism for the delivery of goods and services . The...are from government sources, whereas contributions include cash and dollar value of in-kind services and goods . Investment revenues largely consist of...taking action among those most in need of assistance offers a compelling and admirable example of the good a religious organization can accomplish

Using rapid reviews: an example from a study conducted to inform policy-making.

PubMed

O'Leary, Denise F; Casey, Mary; O'Connor, Laserina; Stokes, Diarmuid; Fealy, Gerard M; O'Brien, Denise; Smith, Rita; McNamara, Martin S; Egan, Claire

2017-03-01

A discussion of the potential use of rapid review approaches in nursing and midwifery research which presents a worked example from a study conducted to inform policy decision-making. Rapid reviews, which can be defined as outputs of a knowledge synthesis approach that involves modifying or omitting elements of a systematic review process due to limited time or resources, are becoming increasingly popular in health research. This paper provides guidance on how a rapid review can be undertaken and discusses the strengths and challenges of the approach. Data from a rapid review of the literature undertaken in 2015 is used as a worked example to highlight one method of undertaking a rapid review. Seeking evidence to inform health policy-making or evidence based practice is a process that can be limited by time constraints, making it difficult to conduct comprehensive systematic reviews. Rapid reviews provide a solution as they are a systematic method of synthesizing evidence quickly. There is no single best way to conduct a rapid review but researchers can ensure they are adhering to best practice by being systematic, having subject and methodological expertise on the review team, reporting the details of the approach they took, highlighting the limitations of the approach, engaging in good evidence synthesis and communicating regularly with end users, other team members and experts. © 2016 John Wiley & Sons Ltd.

Collapse in two good solvents, swelling in two poor solvents: defying the laws of polymer solubility?

NASA Astrophysics Data System (ADS)

Mukherji, Debashish; Marques, Carlos M.; Kremer, Kurt

2018-01-01

In this work we discuss two mirror but distinct phenomena of polymer paradoxical properties in mixed solvents: co-non-solvency and co-solvency. When a polymer collapses in a mixture of two miscible good solvents the phenomenon is known as co-non-solvency, while co-solvency is a phenomenon that is associated with the swelling of a polymer in poor solvent mixtures. A typical example of co-non-solvency is provided by poly(N-isopropylacrylamide) in aqueous alcohol, while poly(methyl methacrylate) in aqueous alcohol shows co-solvency. We discuss these two phenomena to compare their microscopic origins and show that both can be understood within generic universal concepts. A broad range of polymers is therefore expected to exhibit these phenomena where specific chemical details play a lesser role than the appropriate combination of interactions between the trio of molecular components.

Continuity and Change in India’s Foreign Policy: The Next Five Years,

DTIC Science & Technology

1984-01-01

mainly of food products (tea, coffee, rice, cashews , pepper), tobacco, leather goods, cotton textiles, jute products, light engineering goods, and...industrial fasteners ( nuts and bolts), for example, have drawn strong Indian protests, and the protectionist mood in the United States, as reflected in

20 CFR 404.1530 - Need to follow prescribed treatment.

Code of Federal Regulations, 2010 CFR

2010-04-01

... good reason, we will not find you disabled or, if you are already receiving benefits, we will stop paying you benefits. (c) Acceptable reasons for failure to follow prescribed treatment. We will consider... treatment. The following are examples of a good reason for not following treatment: (1) The specific medical...

The Dynamics of Multilateral Exchange

NASA Astrophysics Data System (ADS)

Hausken, Kjell; Moxnes, John F.

The article formulates a dynamic mathematical model where arbitrarily many players produce, consume, exchange, loan, and deposit arbitrarily many goods over time to maximize utility. Consuming goods constitutes a benefit, and producing, exporting, and loaning away goods constitute a cost. Utilities are benefits minus costs, which depend on the exchange ratios and bargaining functions. Three-way exchange occurs when one player acquires, through exchange, one good from another player with the sole purpose of using this good to exchange against the desired good from a third player. Such a triple handshake is not merely a set of double handshakes since the player assigns no interest to the first good in his benefit function. Cognitive and organization costs increase dramatically for higher order exchanges. An exchange theory accounting for media of exchange follows from simple generalization of two-way exchange. The examples of r-way exchange are the triangle trade between Africa, the USA, and England in the 17th and 18th centuries, the hypothetical hypercycle involving RNAs as players and enzymes as goods, and reaction-diffusion processes. The emergence of exchange, and the role of trading agents are discussed. We simulate an example where two-way exchange gives zero production and zero utility, while three-way exchange causes considerable production and positive utility. Maximum utility for each player is reached when exchanges of the same order as the number of players in society are allowed. The article merges micro theory and macro theory within the social, natural, and physical sciences.

Brownfields: Recent federal and Massachusetts developments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Abelson, N.; McCaffery, M.

While EPA`s recent efforts, including its Brownfields Action Agenda, are clearly positive developments, by far most of the action in the Brownfields area has been at the state level. The Massachusetts Clean Sites Initiative is one of more than twenty state programs adopted across the country to encourage Brownfields redevelopment. The Clean Sites Initiative is a good example of using a carrot and not only a stick to address hazardous waste problems. It is also a good example of government, the business community, and other affected stakeholders working together to develop a program that helps achieve shared goals, which ismore » effectively a requirement in the Brownfields area.« less

Asking good clinical research questions and choosing the right study design.

PubMed

Bragge, P

2010-07-01

Clinicians and researchers seek answers to clinical research questions, primarily by accessing the results of clinical research studies. This paper moves the focus of research enquiry from getting answers to developing good clinical research questions. Using worked examples, the steps involved in refining questions drawn from various sources to create 'answerable' clinical research questions using the 'PICO' principle are described. Issues to consider in prioritising clinical research questions are also identified. Theoretical and practical considerations involved in choosing the right study design for a clinical research question are then discussed using the worked examples. These include: Copyright (c) 2010 Elsevier Ltd. All rights reserved.

Biobanks between common good and private interest: the example of umbilical cord blood private biobanks.

PubMed

Onisto, Maurizio; Ananian, Viviana; Caenazzo, Luciana

2011-12-01

Storage of human biological samples and personal data associated with them is organised in Biobanks. In spite of expectation given by biobanks in medicine, their management involved some ethical questions, for example, the need for policies to regulate economic interests, potential commercial use of data (including patents), private sector financing, ownership of samples and benefit sharing. In the context of contributing to the general public interest, we can consider the act of giving biological material to biobanks as a donation, in which the donation constitutes part of a generalised form of reciprocity in which the act of donation contributes to society's common good. Starting from this perspective, we move into a different situation represented by the biobanking of umbilical cord blood for personal use. We used the example of the private biobanking of umbilical cords to demonstrate the restrictive utility of the collection and preservation of cord blood for personal use in private biobanks, in the context of society's common good. In summary, a system based on solidarity seems to be able to guarantee necessary levels of supply for the donation of biological material to biobanks.

United States v. Levin: entrapment by estoppel doctrine applied in Medicare reimbursement context.

PubMed

Shaw, P W; Griffith, R A

1993-01-01

The decision in Levin reaffirms that health care providers should be entitled to rely in good faith on official interpretations and representations by authorized government officials as to the propriety of their conduct under the Medicare program. Although the doctrine of entrapment by estoppel was developed as a due process defense to a criminal prosecution, the fundamental notions of fairness underlying the doctrine should be applicable as well as in a civil action. Thus, the defense of entrapment by estoppel should be available, for example, in the context of civil health care reimbursement recoupment audits, where a provider has acted in reliance on the interpretation of a statute or regulation by the appropriate administrative agency charged with its enforcement.

In search of a metatheory for cognitive development (or, Piaget is dead and I don't feel so good myself).

PubMed

Bjorklund, D F

1997-02-01

With the waning of influence of Piaget's theory and the shortcomings of information-processing perspectives of cognitive growth, cognitive developmentalists lack a common set of broad, overarching principles and assumptions--a metatheory--to guide their research. Developmental biology is suggested as metatheory for cognitive development. Although it is important for developmentalists to understand proximal biological causes (e.g., brain development), most important for such a metatheory is an evolutionary perspective. Some basic principles of evolutionary psychology are introduced, and examples of contemporary research and theory consistent with these ideas are provided.

Predicting charmonium and bottomonium spectra with a quark harmonic oscillator

NASA Technical Reports Server (NTRS)

Norbury, J. W.; Badavi, F. F.; Townsend, L. W.

1986-01-01

The nonrelativistic quark model is applied to heavy (nonrelativistic) meson (two-body) systems to obtain sufficiently accurate predictions of the spin-averaged mass levels of the charmonium and bottomonium spectra as an example of the three-dimensional harmonic oscillator. The present calculations do not include any spin dependence, but rather, mass values are averaged for different spins. Results for a charmed quark mass value of 1500 MeV/c-squared show that the simple harmonic oscillator model provides good agreement with experimental values for 3P states, and adequate agreement for the 3S1 states.

Uncertainty Estimation Cheat Sheet for Probabilistic Risk Assessment

NASA Technical Reports Server (NTRS)

Britton, Paul; Al Hassan, Mohammad; Ring, Robert

2017-01-01

Quantitative results for aerospace engineering problems are influenced by many sources of uncertainty. Uncertainty analysis aims to make a technical contribution to decision-making through the quantification of uncertainties in the relevant variables as well as through the propagation of these uncertainties up to the result. Uncertainty can be thought of as a measure of the 'goodness' of a result and is typically represented as statistical dispersion. This paper will explain common measures of centrality and dispersion; and-with examples-will provide guidelines for how they may be estimated to ensure effective technical contributions to decision-making.

A firefly algorithm for solving competitive location-design problem: a case study

NASA Astrophysics Data System (ADS)

Sadjadi, Seyed Jafar; Ashtiani, Milad Gorji; Ramezanian, Reza; Makui, Ahmad

2016-12-01

This paper aims at determining the optimal number of new facilities besides specifying both the optimal location and design level of them under the budget constraint in a competitive environment by a novel hybrid continuous and discrete firefly algorithm. A real-world application of locating new chain stores in the city of Tehran, Iran, is used and the results are analyzed. In addition, several examples have been solved to evaluate the efficiency of the proposed model and algorithm. The results demonstrate that the performed method provides good-quality results for the test problems.

Fused thiophene-based conjugated polymers and their use in optoelectronic devices

DOEpatents

Facchetti, Antonio; Marks, Tobin J; Takai, Atsuro; Seger, Mark; Chen, Zhihua

2015-11-03

The present teachings relate to certain polymeric compounds and their use as organic semiconductors in organic and hybrid optical, optoelectronic, and/or electronic devices such as photovoltaic cells, light emitting diodes, light emitting transistors, and field effect transistors. The disclosed compounds can provide improved device performance, for example, as measured by power conversion efficiency, fill factor, open circuit voltage, field-effect mobility, on/off current ratios, and/or air stability when used in photovoltaic cells or transistors. The disclosed compounds can have good solubility in common solvents enabling device fabrication via solution processes.

26 CFR 1.6115-1 - Disclosure requirements for quid pro quo contributions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 26 Internal Revenue 13 2010-04-01 2010-04-01 false Disclosure requirements for quid pro quo contributions. 1.6115-1 Section 1.6115-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY... unique qualities of the goods or services that are being valued. (3) Examples. The following examples...

Studying and Working Abroad. Leonardo da Vinci Series: Good Practices.

ERIC Educational Resources Information Center

Commission of the European Communities, Brussels (Belgium). Directorate-General for Education and Culture.

This document profiles recent successful examples of students studying and working abroad as part of the European Commission's Leonardo da Vinci program, which is designed to give students across the European Union the opportunity to experience vocational training in a foreign country. The following examples are presented: (1) 3 Finnish students…

16 CFR 803.9 - Filing fee.

Code of Federal Regulations, 2014 CFR

2014-01-01

... minus $1 million. In this example, since “A” is able in good faith to reasonably estimate the... 16 Commercial Practices 1 2014-01-01 2014-01-01 false Filing fee. 803.9 Section 803.9 Commercial... of the Department of Justice. Examples: 1. “A” wishes to acquire voting securities issued by B, where...

Is Children's Free School Meal "Eligibility" a Good Proxy for Family Income?

ERIC Educational Resources Information Center

Hobbs, Graham; Vignoles, Anna

2010-01-01

Family income is an important factor associated with children's educational achievement. However, key areas of UK research (for example, on socially segregated schooling) and policy (for example, the allocation of funding to schools) rely on children's free school meal (FSM) "eligibility" to proxy family income. This article examines the…

Development of Benchmark Examples for Quasi-Static Delamination Propagation and Fatigue Growth Predictions

NASA Technical Reports Server (NTRS)

Krueger, Ronald

2012-01-01

The development of benchmark examples for quasi-static delamination propagation and cyclic delamination onset and growth prediction is presented and demonstrated for Abaqus/Standard. The example is based on a finite element model of a Double-Cantilever Beam specimen. The example is independent of the analysis software used and allows the assessment of the automated delamination propagation, onset and growth prediction capabilities in commercial finite element codes based on the virtual crack closure technique (VCCT). First, a quasi-static benchmark example was created for the specimen. Second, based on the static results, benchmark examples for cyclic delamination growth were created. Third, the load-displacement relationship from a propagation analysis and the benchmark results were compared, and good agreement could be achieved by selecting the appropriate input parameters. Fourth, starting from an initially straight front, the delamination was allowed to grow under cyclic loading. The number of cycles to delamination onset and the number of cycles during delamination growth for each growth increment were obtained from the automated analysis and compared to the benchmark examples. Again, good agreement between the results obtained from the growth analysis and the benchmark results could be achieved by selecting the appropriate input parameters. The benchmarking procedure proved valuable by highlighting the issues associated with choosing the input parameters of the particular implementation. Selecting the appropriate input parameters, however, was not straightforward and often required an iterative procedure. Overall the results are encouraging, but further assessment for mixed-mode delamination is required.

Development of Benchmark Examples for Static Delamination Propagation and Fatigue Growth Predictions

NASA Technical Reports Server (NTRS)

Kruger, Ronald

2011-01-01

The development of benchmark examples for static delamination propagation and cyclic delamination onset and growth prediction is presented and demonstrated for a commercial code. The example is based on a finite element model of an End-Notched Flexure (ENF) specimen. The example is independent of the analysis software used and allows the assessment of the automated delamination propagation, onset and growth prediction capabilities in commercial finite element codes based on the virtual crack closure technique (VCCT). First, static benchmark examples were created for the specimen. Second, based on the static results, benchmark examples for cyclic delamination growth were created. Third, the load-displacement relationship from a propagation analysis and the benchmark results were compared, and good agreement could be achieved by selecting the appropriate input parameters. Fourth, starting from an initially straight front, the delamination was allowed to grow under cyclic loading. The number of cycles to delamination onset and the number of cycles during stable delamination growth for each growth increment were obtained from the automated analysis and compared to the benchmark examples. Again, good agreement between the results obtained from the growth analysis and the benchmark results could be achieved by selecting the appropriate input parameters. The benchmarking procedure proved valuable by highlighting the issues associated with the input parameters of the particular implementation. Selecting the appropriate input parameters, however, was not straightforward and often required an iterative procedure. Overall, the results are encouraging but further assessment for mixed-mode delamination is required.

Development and Application of Benchmark Examples for Mode II Static Delamination Propagation and Fatigue Growth Predictions

NASA Technical Reports Server (NTRS)

Krueger, Ronald

2011-01-01

The development of benchmark examples for static delamination propagation and cyclic delamination onset and growth prediction is presented and demonstrated for a commercial code. The example is based on a finite element model of an End-Notched Flexure (ENF) specimen. The example is independent of the analysis software used and allows the assessment of the automated delamination propagation, onset and growth prediction capabilities in commercial finite element codes based on the virtual crack closure technique (VCCT). First, static benchmark examples were created for the specimen. Second, based on the static results, benchmark examples for cyclic delamination growth were created. Third, the load-displacement relationship from a propagation analysis and the benchmark results were compared, and good agreement could be achieved by selecting the appropriate input parameters. Fourth, starting from an initially straight front, the delamination was allowed to grow under cyclic loading. The number of cycles to delamination onset and the number of cycles during delamination growth for each growth increment were obtained from the automated analysis and compared to the benchmark examples. Again, good agreement between the results obtained from the growth analysis and the benchmark results could be achieved by selecting the appropriate input parameters. The benchmarking procedure proved valuable by highlighting the issues associated with choosing the input parameters of the particular implementation. Selecting the appropriate input parameters, however, was not straightforward and often required an iterative procedure. Overall the results are encouraging, but further assessment for mixed-mode delamination is required.

The Biological Relevance of Artificial Life: Lessons from Artificial Intelligence

NASA Technical Reports Server (NTRS)

Colombano, Silvano

2000-01-01

There is no fundamental reason why A-life couldn't simply be a branch of computer science that deals with algorithms that are inspired by, or emulate biological phenomena. However, if these are the limits we place on this field, we miss the opportunity to help advance Theoretical Biology and to contribute to a deeper understanding of the nature of life. The history of Artificial Intelligence provides a good example, in that early interest in the nature of cognition quickly was lost to the process of building tools, such as "expert systems" that, were certainly useful, but provided little insight in the nature of cognition. Based on this lesson, I will discuss criteria for increasing the biological relevance of A-life and the probability that this field may provide a theoretical foundation for Biology.

Order Without Intellectual Property Law: Open Science in Influenza.

PubMed

Kapczynski, Amy

Today, intellectual property (IP) scholars accept that IP as an approach to information production has serious limits. But what lies beyond IP? A new literature on "intellectual production without IP" (or "IP without IP") has emerged to explore this question, but its examples and explanations have yet to convince skeptics. This Article reorients this new literature via a study of a hard case: a global influenza virus-sharing network that has for decades produced critically important information goods, at significant expense, and in a loose-knit group--all without recourse to IP. I analyze the Network as an example of "open science," a mode of information production that differs strikingly from conventional IP, and yet that successfully produces important scientific goods in response to social need. The theory and example developed here refute the most powerful criticisms of the emerging "IP without IP" literature, and provide a stronger foundation for this important new field. Even where capital costs are high, creation without IP can be reasonably effective in social terms, if it can link sources of funding to reputational and evaluative feedback loops like those that characterize open science. It can also be sustained over time, even by loose-knit groups and where the stakes are high, because organizations and other forms of law can help to stabilize cooperation. I also show that contract law is well suited to modes of information production that rely upon a "supply side" rather than "demand side" model. In its most important instances, "order without IP" is not order without governance, nor order without law. Recognizing this can help us better ground this new field, and better study and support forms of knowledge production that deserve our attention, and that sometimes sustain our very lives.

Agricultural Impacts on Water Resources: Recommendations for Successful Applied Research

NASA Astrophysics Data System (ADS)

Harmel, D.

2014-12-01

We, as water resource professionals, are faced with a truly monumental challenge - that is feeding the world's growing population and ensuring it has an adequate supply of clean water. As researchers and educators it is good for us to regularly remember that our research and outreach efforts are critical to people around the world, many of whom are desperate for solutions to water quality and supply problems and their impacts on food supply, land management, and ecosystem protection. In this presentation, recommendations for successful applied research on agricultural impacts on water resources will be provided. The benefits of building multidisciplinary teams will be illustrated with examples related to the development and world-wide application of the ALMANAC, SWAT, and EPIC/APEX models. The value of non-traditional partnerships will be shown by the Soil Health Partnership, a coalition of agricultural producers, chemical and seed companies, and environmental advocacy groups. The results of empowering decision-makers with useful data will be illustrated with examples related to bacteria source and transport data and the MANAGE database, which contains runoff nitrogen and phosphorus data for cultivated, pasture, and forest land uses. The benefits of focusing on sustainable solutions will be shown through examples of soil testing, fertilizers application, on-farm profit analysis, and soil health assessment. And the value of welcoming criticism will be illustrated by the development of a framework to estimate and publish uncertainty in measured discharge and water quality data. The good news for researchers is that the agricultural industry is faced with profitability concerns and the need to wisely utilize soil and water resources, and simultaneously state and federal agencies crave sound-science to improve decision making, policy, and regulation. Thus, the audience for and beneficiaries of agricultural research are ready and hungry for applied research results.

Drivers of U.S. mineral demand

USGS Publications Warehouse

Sznopek, John L.

2006-01-01

Introduction: The word 'demand' has different meanings for different people. To some, it means their 'wants and needs,' to others it is what they consume. Yet, when considering economics, demand refers to the specific amounts of goods or services that individuals will purchase at various prices. Demand is measured over a given time period. It is determined by a number of factors including income, tastes, and the price of complementary and substitute goods. In this paper, the term consumption is used fairly synonymously with the term demand. Most mineral commodities, like iron ore, copper, zinc, and gravel, are intermediate goods, which means that they are used in the production of other goods, called final goods. Demand for intermediate goods is called derived demand because such demand is derived from the demand for final goods. When demand increases for a commodity, generally the price rises. With everything else held constant, this increases the profits for those who provide this commodity. Normally, this would increase profits of existing producers and attract new producers to the market. When demand for a commodity decreases, generally the price falls. Normally, this would cause profits to fall and, as a consequence, the least efficient firms may be forced from the industry. Demand changes for specific materials as final goods or production techniques are reengineered while maintaining or improving product performance, for example, the use of aluminum in the place of copper in long distance electrical transmission lines or plastic replacing steel in automobile bumpers. Substitution contributes to efficient material usage by utilizing cheaper or technically superior materials. In this way, it may also alleviate materials scarcity. If a material becomes relatively scarce (and thus more expensive), a more abundant (and less expensive) material generally replaces it (Wagner and others, 2003, p. 91).

Special Teaching for Special Children? Pedagogies for Inclusion. Inclusive Education

ERIC Educational Resources Information Center

Lewis, Ann, Ed.; Norwich, Brahm, Ed.

2004-01-01

Some special needs groups (for example dyslexia) have argued strongly for the need for particular specialist approaches. In contrast, many proponents of inclusion have argued that "good teaching is good teaching for all" and that all children benefit from similar approaches. Both positions fail to scrutinise this issue rigorously and…

32 CFR 536.132 - Procedure for processing UCMJ claims.

Code of Federal Regulations, 2011 CFR

2011-07-01

... the claim determines there is good cause for delay. Lack of knowledge of the existence of Article 139, or lack of knowledge of the identity of the offender, are examples of good cause for delay. (b) Form... procedures. When assessment action on a particular claim will be unduly delayed, the claims office supporting...

32 CFR 536.132 - Procedure for processing UCMJ claims.

Code of Federal Regulations, 2010 CFR

2010-07-01

... the claim determines there is good cause for delay. Lack of knowledge of the existence of Article 139, or lack of knowledge of the identity of the offender, are examples of good cause for delay. (b) Form... the claim to the commander who exercises SPCMCA jurisdiction over the soldier for assessment. The...

Re-Using Today's Metadata for Tomorrow's Research: Five Practical Examples for Enhancing Access to Digital Collections

ERIC Educational Resources Information Center

Tzoc, Elias

2011-01-01

According to the "Framework of Guidance for Building Good Digital Collections," a good collection is broadly available and avoids unnecessary impediments to use. Two challenges, however, are the constant change in users' expectations and the increasing volume of information in local repositories. Therefore, as academic and research…

High-performance parallel computing in the classroom using the public goods game as an example

NASA Astrophysics Data System (ADS)

Perc, Matjaž

2017-07-01

The use of computers in statistical physics is common because the sheer number of equations that describe the behaviour of an entire system particle by particle often makes it impossible to solve them exactly. Monte Carlo methods form a particularly important class of numerical methods for solving problems in statistical physics. Although these methods are simple in principle, their proper use requires a good command of statistical mechanics, as well as considerable computational resources. The aim of this paper is to demonstrate how the usage of widely accessible graphics cards on personal computers can elevate the computing power in Monte Carlo simulations by orders of magnitude, thus allowing live classroom demonstration of phenomena that would otherwise be out of reach. As an example, we use the public goods game on a square lattice where two strategies compete for common resources in a social dilemma situation. We show that the second-order phase transition to an absorbing phase in the system belongs to the directed percolation universality class, and we compare the time needed to arrive at this result by means of the main processor and by means of a suitable graphics card. Parallel computing on graphics processing units has been developed actively during the last decade, to the point where today the learning curve for entry is anything but steep for those familiar with programming. The subject is thus ripe for inclusion in graduate and advanced undergraduate curricula, and we hope that this paper will facilitate this process in the realm of physics education. To that end, we provide a documented source code for an easy reproduction of presented results and for further development of Monte Carlo simulations of similar systems.

Equity and financing for sexual and reproductive health service delivery: current innovations.

PubMed

Montagu, Dominic; Graff, Maura

2009-07-01

National and international decisions on financing for sexual and reproductive health (SRH) services have profound effects on the type, unit costs and distribution of SRH commodities and services produced, and on their availability and consumption. Much international and national funding is politically driven and is doing little for equity and quality improvement. Financing remains a significant challenge in most developing countries and demands creative responses. While no "one-size-fits-all" solution exists, there are numerous ongoing examples of successful innovations, many of which are focusing on resource pooling and on purchasing or subsidising SRH services. In this article we have used interviews, grey literature and presentations made at a range of recent public fora to identify new and innovative ways of financing SRH services so as to increase equity in developing countries. Because SRH services are often of low value as a personal good but high value as a public good, we summarise the issues from a societal perspective, highlighting the importance of financing and policy decisions for SRH services. We provide a structured overview of what novel approaches to financing appear to have positive effects in a range of developing countries. Targeting, government payment mechanisms, subsidy delivery and co-financing for sustainability are highlighted as showing particular promise. Examples are used throughout the article to illustrate innovative strategies.

Development and Application of Benchmark Examples for Mixed-Mode I/II Quasi-Static Delamination Propagation Predictions

NASA Technical Reports Server (NTRS)

Krueger, Ronald

2012-01-01

The development of benchmark examples for quasi-static delamination propagation prediction is presented and demonstrated for a commercial code. The examples are based on finite element models of the Mixed-Mode Bending (MMB) specimen. The examples are independent of the analysis software used and allow the assessment of the automated delamination propagation prediction capability in commercial finite element codes based on the virtual crack closure technique (VCCT). First, quasi-static benchmark examples were created for the specimen. Second, starting from an initially straight front, the delamination was allowed to propagate under quasi-static loading. Third, the load-displacement relationship from a propagation analysis and the benchmark results were compared, and good agreement could be achieved by selecting the appropriate input parameters. Good agreement between the results obtained from the automated propagation analysis and the benchmark results could be achieved by selecting input parameters that had previously been determined during analyses of mode I Double Cantilever Beam and mode II End Notched Flexure specimens. The benchmarking procedure proved valuable by highlighting the issues associated with choosing the input parameters of the particular implementation. Overall the results are encouraging, but further assessment for mixed-mode delamination fatigue onset and growth is required.

3-D velocity structure model for long-period ground motion simulation of the hypothetical Nankai Earthquake

NASA Astrophysics Data System (ADS)

Kagawa, T.; Petukhin, A.; Koketsu, K.; Miyake, H.; Murotani, S.; Tsurugi, M.

2010-12-01

Three dimensional velocity structure model of southwest Japan is provided to simulate long-period ground motions due to the hypothetical subduction earthquakes. The model is constructed from numerous physical explorations conducted in land and offshore areas and observational study of natural earthquakes. Any available information is involved to explain crustal structure and sedimentary structure. Figure 1 shows an example of cross section with P wave velocities. The model has been revised through numbers of simulations of small to middle earthquakes as to have good agreement with observed arrival times, amplitudes, and also waveforms including surface waves. Figure 2 shows a comparison between Observed (dash line) and simulated (solid line) waveforms. Low velocity layers have added on seismological basement to reproduce observed records. The thickness of the layer has been adjusted through iterative analysis. The final result is found to have good agreement with the results from other physical explorations; e.g. gravity anomaly. We are planning to make long-period (about 2 to 10 sec or longer) simulations of ground motion due to the hypothetical Nankai Earthquake with the 3-D velocity structure model. As the first step, we will simulate the observed ground motions of the latest event occurred in 1946 to check the source model and newly developed velocity structure model. This project is partly supported by Integrated Research Project for Long-Period Ground Motion Hazard Maps by Ministry of Education, Culture, Sports, Science and Technology (MEXT). The ground motion data used in this study were provided by National Research Institute for Earth Science and Disaster Prevention Disaster (NIED). Figure 1 An example of cross section with P wave velocities Figure 2 Observed (dash line) and simulated (solid line) waveforms due to a small earthquake

Artificial intelligence in sports on the example of weight training.

PubMed

Novatchkov, Hristo; Baca, Arnold

2013-01-01

The overall goal of the present study was to illustrate the potential of artificial intelligence (AI) techniques in sports on the example of weight training. The research focused in particular on the implementation of pattern recognition methods for the evaluation of performed exercises on training machines. The data acquisition was carried out using way and cable force sensors attached to various weight machines, thereby enabling the measurement of essential displacement and force determinants during training. On the basis of the gathered data, it was consequently possible to deduce other significant characteristics like time periods or movement velocities. These parameters were applied for the development of intelligent methods adapted from conventional machine learning concepts, allowing an automatic assessment of the exercise technique and providing individuals with appropriate feedback. In practice, the implementation of such techniques could be crucial for the investigation of the quality of the execution, the assistance of athletes but also coaches, the training optimization and for prevention purposes. For the current study, the data was based on measurements from 15 rather inexperienced participants, performing 3-5 sets of 10-12 repetitions on a leg press machine. The initially preprocessed data was used for the extraction of significant features, on which supervised modeling methods were applied. Professional trainers were involved in the assessment and classification processes by analyzing the video recorded executions. The so far obtained modeling results showed good performance and prediction outcomes, indicating the feasibility and potency of AI techniques in assessing performances on weight training equipment automatically and providing sportsmen with prompt advice. Key pointsArtificial intelligence is a promising field for sport-related analysis.Implementations integrating pattern recognition techniques enable the automatic evaluation of data measurements.Artificial neural networks applied for the analysis of weight training data show good performance and high classification rates.

[Inequalities in access to care in Africa].

PubMed

Livinec, Bertrand; Milleliri, Jean-Marie; Rey, Jean-Loup; Saliou, Pierre

2013-05-01

Social inequalities in health are increasingly in the news in Africa. While appeals, international declarations and new strategies for health in Africa have succeeded one another over the years, we must admit that the health inequalities are increasing. It is perhaps time to take health out of its compartment and understand that it is one of the components of overall development and that we cannot act effectively against these health inequalities unless we also act on the pressing need to see all States (in the North and South) finally meet their financial commitments, demand of African leaders that they provide good government and fight against corruption, the leaders of African good government and a fight against corruption, and finally ensure that the strategies proposed in Africa focus on the health priorities of each country. If we mention the Scandinavian example, we must admit that the Nordic countries have demonstrated their capacity to obtain excellent results in health, to narrow social inequalities, and provide public transparency and aid to development. They constitute today an excellent example for most Western countries and for African countries - and also for African and western civil societies, which can be inspired by the concrete measures of transparency and strong public activity, which promote improvement in the overall statistics of their societies, in particular, in health. Accordingly we propose a new approach that looks at health statistics in the light of inequalities (especially via the Gini coefficient) and public transparency (especially via the benchmarks of perceived corruption). A New Deal for health in Africa is needed, and all the organization involved should be asked to act together for a holistic public health vision that will benefit the populations of Africa. Health cannot be separated from a political, ethical and equitable vision of society.

Artificial Intelligence in Sports on the Example of Weight Training

PubMed Central

Novatchkov, Hristo; Baca, Arnold

2013-01-01

The overall goal of the present study was to illustrate the potential of artificial intelligence (AI) techniques in sports on the example of weight training. The research focused in particular on the implementation of pattern recognition methods for the evaluation of performed exercises on training machines. The data acquisition was carried out using way and cable force sensors attached to various weight machines, thereby enabling the measurement of essential displacement and force determinants during training. On the basis of the gathered data, it was consequently possible to deduce other significant characteristics like time periods or movement velocities. These parameters were applied for the development of intelligent methods adapted from conventional machine learning concepts, allowing an automatic assessment of the exercise technique and providing individuals with appropriate feedback. In practice, the implementation of such techniques could be crucial for the investigation of the quality of the execution, the assistance of athletes but also coaches, the training optimization and for prevention purposes. For the current study, the data was based on measurements from 15 rather inexperienced participants, performing 3-5 sets of 10-12 repetitions on a leg press machine. The initially preprocessed data was used for the extraction of significant features, on which supervised modeling methods were applied. Professional trainers were involved in the assessment and classification processes by analyzing the video recorded executions. The so far obtained modeling results showed good performance and prediction outcomes, indicating the feasibility and potency of AI techniques in assessing performances on weight training equipment automatically and providing sportsmen with prompt advice. Key points Artificial intelligence is a promising field for sport-related analysis. Implementations integrating pattern recognition techniques enable the automatic evaluation of data measurements. Artificial neural networks applied for the analysis of weight training data show good performance and high classification rates. PMID:24149722

Surprise! From CEOs to Navy Seals: How a Select Group of Professionals Prepare for and Respond to the Unexpected

DTIC Science & Technology

2013-01-01

the 1986 Chernobyl disaster was a good example of a UU.7 The disaster itself was entirely unexpected and presented a variety of diplomatic challenges...This Chernobyl example helps to clarify an important point: A UU need not be considered an impossible event—certainly, a nuclear plant meltdown

Dressing Down

NASA Technical Reports Server (NTRS)

Schabes, Harvey

2003-01-01

Smiles and laughter reduce stress. They also renew energy and trust in ourselves and others. A characteristic of any good project manager is his or her willingness to challenge the conventional way of doing things. Use whatever tools you have available, including a sense of humor. Do you have examples of how you learned from experience, especially examples that challenged the status quo?

Minerals Price Increases and Volatility: Causes and Consequences

DTIC Science & Technology

2008-10-03

goods , used to make final products, rose 8%. Both rates are triple those at this time [in 2007].8 A 2008 report for Lehman Brothers, a New York-based...products, which are the most widely used intermediate goods produced from iron ore (all ferrous scrap was originally processed from iron ore). Some...prices, even though demand for final goods using steel products was not nearly so robust. The clearest example is in sheet steel, which, in the first

Scientific R&D: time to revise the rules?

PubMed

Crump, Andy

2004-11-01

For several decades scientific R&D has been failing communities around the world, especially in developing countries, by not producing an adequate level of benefits (for example, improved health and living standards) and essential public goods (for example, the provision of safe water, sanitation and energy). It is time for a complete overhaul of the R&D process, with a comprehensive review of the mechanisms by which R&D is financed, how and where the work and results are published and disseminated, how the results and knowledge are exploited, and how ownership is decided. This is particularly important for public goods, for which there is often no market or prospect of commercial return or profit.

Emerging Leadership Vistas (International Leadership Symposia Series. Volume 8. Held in Lubbock, Texas July 23-27, 1985

DTIC Science & Technology

1988-06-01

classification of some of the variables. For example , she sees charisma as a person variable whereas Sash- kin and Fulmer consider it a behavior. Similarly... example , good and bad leaders may be culture specific. If this notion is extended to organizational cultures (an important aspect of Sashkin and Ful...Celestial Seasonings might be an example . In cell 2, where actions elicit consequences but do not reflect shared values or understanding, we have alienation

The Contribution of Particle Swarm Optimization to Three-Dimensional Slope Stability Analysis

PubMed Central

A Rashid, Ahmad Safuan; Ali, Nazri

2014-01-01

Over the last few years, particle swarm optimization (PSO) has been extensively applied in various geotechnical engineering including slope stability analysis. However, this contribution was limited to two-dimensional (2D) slope stability analysis. This paper applied PSO in three-dimensional (3D) slope stability problem to determine the critical slip surface (CSS) of soil slopes. A detailed description of adopted PSO was presented to provide a good basis for more contribution of this technique to the field of 3D slope stability problems. A general rotating ellipsoid shape was introduced as the specific particle for 3D slope stability analysis. A detailed sensitivity analysis was designed and performed to find the optimum values of parameters of PSO. Example problems were used to evaluate the applicability of PSO in determining the CSS of 3D slopes. The first example presented a comparison between the results of PSO and PLAXI-3D finite element software and the second example compared the ability of PSO to determine the CSS of 3D slopes with other optimization methods from the literature. The results demonstrated the efficiency and effectiveness of PSO in determining the CSS of 3D soil slopes. PMID:24991652

The contribution of particle swarm optimization to three-dimensional slope stability analysis.

PubMed

Kalatehjari, Roohollah; Rashid, Ahmad Safuan A; Ali, Nazri; Hajihassani, Mohsen

2014-01-01

Over the last few years, particle swarm optimization (PSO) has been extensively applied in various geotechnical engineering including slope stability analysis. However, this contribution was limited to two-dimensional (2D) slope stability analysis. This paper applied PSO in three-dimensional (3D) slope stability problem to determine the critical slip surface (CSS) of soil slopes. A detailed description of adopted PSO was presented to provide a good basis for more contribution of this technique to the field of 3D slope stability problems. A general rotating ellipsoid shape was introduced as the specific particle for 3D slope stability analysis. A detailed sensitivity analysis was designed and performed to find the optimum values of parameters of PSO. Example problems were used to evaluate the applicability of PSO in determining the CSS of 3D slopes. The first example presented a comparison between the results of PSO and PLAXI-3D finite element software and the second example compared the ability of PSO to determine the CSS of 3D slopes with other optimization methods from the literature. The results demonstrated the efficiency and effectiveness of PSO in determining the CSS of 3D soil slopes.

History of optics: a modern teaching tool

NASA Astrophysics Data System (ADS)

Vazquez, D.; Gonzalez-Cano, A.; Diaz-Herrera, N.; Llombart, N.; Alda, J.

2012-10-01

The history of optics is a very rich field of science and it is possible to find many simple and significant examples of the application and success of the experimental method and therefore is a very good tool to transmit to the student the way science proceeds and to introduce the right spirit of critical analysis, building and testing of models, etc. Optical phenomena are specially well suited for this because in fact optical observations and experiments have made science advance in a crucial way in many different periods of history, because they are in many cases quite visual, quite simple in concept and it is very easy to produce experimental setups in classrooms. Also, the intrinsic multidisciplinary character of Optics, which is a subject that has historically influenced in a notorious way fields as art, philosophy, religion and cultural and social studies in general, provide a very wide frame that permits to apply these examples to many different auditories. We present here some reflections about the role that history of optics can play in teaching and show some real examples of its application during the many years that we have been employing it in the context of the Optics School of the Complutense University of Madrid, Spain.

Chemistry Perfumes Your Daily Life

NASA Astrophysics Data System (ADS)

Fortineau, Anne-Dominique

2004-01-01

The use of perfumes can be tracked back to many early civilizations. Historically, perfumes were composed exclusively of natural ingredients, mainly essential oils, and were reserved for the wealthiest people. The use of synthetic ingredients marked the beginning of modern perfumery at the end of the 19th century. Nowadays, perfumes are available to everyone and are present in a wide range of consumer goods. The methods used to extract perfume ingredients from their natural sources have changed over time as technology has advanced. Depending on the material, expression, distillation, and solvent extraction are the main techniques used to extract the odorant components from a natural source. Synthetic organic chemistry has provided perfumers with novel ingredients that are cheaper and more stable than many natural materials over the years. Today, more than 3000 fragrance ingredients are estimated to be available to perfumers to create a harmonious composition of head (for example, citrusy), heart (for example, fruity floral) and base notes (for example, musky). Future developments and uses of perfume are endless and as Ernest Beaux, the perfumer who created Chanel N85, once said, "In perfumery the future lies primarily in the hands of the chemists." Featured on the Cover See Featured Molecules .

Advancing mangrove macroecology

USGS Publications Warehouse

Rivera-Monroy, Victor H.; Osland, Michael J.; Day, John W.; Ray, Santanu; Rovai, Andre S.; Day, Richard H.; Mukherjee, Joyita; Rivera-Monroy, Victor H.; Lee, Shing Yip; Kristensen, Erik; Twilley, Robert R.

2017-01-01

Mangrove forests provide a wide range of ecosystem services to society, yet they are among the most anthropogenically impacted coastal ecosystems in the world. In this chapter, we discuss and provide examples for how macroecology can advance our understanding of mangrove ecosystems. Macroecology is broadly defined as a discipline that uses statistical analyses to investigate large-scale, universal patterns in the distribution, abundance, diversity, and organization of species and ecosystems, including the scaling of ecological processes and structural and functional relationships. Macroecological methods can be used to advance our understanding of how non-linear responses in natural systems can be triggered by human impacts at local, regional, and global scales. Although macroecology has the potential to gain knowledge on universal patterns and processes that govern mangrove ecosystems, the application of macroecological methods to mangroves has historically been limited by constraints in data quality and availability. Here we provide examples that include evaluations of the variation in mangrove forest ecosystem structure and function in relation to macroclimatic drivers (e.g., temperature and rainfall regimes) and climate change. Additional examples include work focused upon the continental distribution of aboveground net primary productivity and carbon storage, which are rapidly advancing research areas. These examples demonstrate the value of a macroecological perspective for the understanding of global- and regional-scale effects of both changing environmental conditions and management actions on ecosystem structure, function, and the supply of goods and services. We also present current trends in mangrove modeling approaches and their potential utility to test hypotheses about mangrove structural and functional properties. Given the gap in relevant experimental work at the regional scale, we also discuss the potential use of mangrove restoration and rehabilitation projects as macroecological studies that advance the critical selection and conservation of ecosystem services when managing mangrove resources. Future work to further incorporate macroecology into mangrove research will require a concerted effort by research groups and institutions to launch research initiatives and synthesize data collected across broad biogeographic regions.

The Hundred Person Wellness Project and Google's Baseline Study: medical revolution or unnecessary and potentially harmful over-testing?

PubMed

Diamandis, Eleftherios P

2015-01-09

The Hundred Person Wellness Project is an ambitious pilot undertaking, which aims to intensely monitor 100 individuals over 10 months. Patients with abnormal findings will be treated, in hopes that this early intervention will avoid, or delay, symptomatic disease. Google's "Baseline Study" is of similar scope and will enroll 10,000 people over 2 to 3 years. I here speculate that these approaches will likely not be effective in preventing disease, but instead, lead to unnecessary and potentially harmful interventions. Examples from the cancer screening experience over the last 30 years are provided, which show that intensive testing may uncover indolent disease or incidental findings which, when treated, may cause more harm than good. Additional examples show that aggressive treatments for cancer and other diseases do not always lead to better patient outcomes. I conclude that the recent advances in omics provide us with unprecedented opportunities for high content clinical testing, but such testing should be used with caution to avoid the harmful consequences of over-diagnosis and over-treatment. Despite the detailed rebuttals by Hood and colleagues in another commentary in BMC Medicine, time will show the actual benefits and harms of these ambitious initiatives.

Suicide index reduction in Slovenia: the impact of primary care provision.

PubMed

Beškovnik, Lucija; Juričič, Nuša Konec; Svab, Vesna

2011-03-01

Background Education of primary care providers about diagnosis and treatment of depression and anxiety is an evidence-based suicide prevention measure.Aim To analyse suicide index, mental health epidemiological data and primary care provision in Slovenian regions and to identify examples of good suicide prevention practices in different Slovenian regions.Methods Analysis of existent epidemiological data on mental health in Slovenia.Results Anxiety and depression are the most common complaints in a representative sample of the Slovene population. The number of suicides in Slovenia had been dropping in the period from 2002 to 2006 and was again slowly rising in 2008. The number of visits to family physicians' practices because of mental health problems is low in comparison to other European countries, which might be attributed also to the high workload of family physicians. Suicide prevention programmes follow the example of the Suicide Prevention Project in the central-east region of Slovenia. This programme is based on education of primary care providers and the general public about recognition and treatment of depression in line with international guidelines.Conclusions The differentiation of causes for suicide reduction needs further research, as well as urgent improvement in the accessibility of primary care teams in Slovenia.

Suicide index reduction in Slovenia: the impact of primary care provision

PubMed Central

2011-01-01

Background Education of primary care providers about diagnosis and treatment of depression and anxiety is an evidence-based suicide prevention measure. Aim To analyse suicide index, mental health epidemiological data and primary care provision in Slovenian regions and to identify examples of good suicide prevention practices in different Slovenian regions. Methods Analysis of existent epidemiological data on mental health in Slovenia. Results Anxiety and depression are the most common complaints in a representative sample of the Slovene population. The number of suicides in Slovenia had been dropping in the period from 2002 to 2006 and was again slowly rising in 2008. The number of visits to family physicians' practices because of mental health problems is low in comparison to other European countries, which might be attributed also to the high workload of family physicians. Suicide prevention programmes follow the example of the Suicide Prevention Project in the central-east region of Slovenia. This programme is based on education of primary care providers and the general public about recognition and treatment of depression in line with international guidelines. Conclusions The differentiation of causes for suicide reduction needs further research, as well as urgent improvement in the accessibility of primary care teams in Slovenia. PMID:22479292

Multidisciplinary approaches to climate change questions

USGS Publications Warehouse

Middleton, Beth A.; LePage, Ben A.

2011-01-01

Multidisciplinary approaches are required to address the complex environmental problems of our time. Solutions to climate change problems are good examples of situations requiring complex syntheses of ideas from a vast set of disciplines including science, engineering, social science, and the humanities. Unfortunately, most ecologists have narrow training, and are not equipped to bring their environmental skills to the table with interdisciplinary teams to help solve multidisciplinary problems. To address this problem, new graduate training programs and workshops sponsored by various organizations are providing opportunities for scientists and others to learn to work together in multidisciplinary teams. Two examples of training in multidisciplinary thinking include those organized by the Santa Fe Institute and Dahlem Workshops. In addition, many interdisciplinary programs have had successes in providing insight into climate change problems including the International Panel on Climate Change, the Joint North American Carbon Program, the National Academy of Science Research Grand Challenges Initiatives, and the National Academy of Science. These programs and initiatives have had some notable success in outlining some of the problems and solutions to climate change. Scientists who can offer their specialized expertise to interdisciplinary teams will be more successful in helping to solve the complex problems related to climate change.

Statistical Methodology for the Analysis of Repeated Duration Data in Behavioral Studies.

PubMed

Letué, Frédérique; Martinez, Marie-José; Samson, Adeline; Vilain, Anne; Vilain, Coriandre

2018-03-15

Repeated duration data are frequently used in behavioral studies. Classical linear or log-linear mixed models are often inadequate to analyze such data, because they usually consist of nonnegative and skew-distributed variables. Therefore, we recommend use of a statistical methodology specific to duration data. We propose a methodology based on Cox mixed models and written under the R language. This semiparametric model is indeed flexible enough to fit duration data. To compare log-linear and Cox mixed models in terms of goodness-of-fit on real data sets, we also provide a procedure based on simulations and quantile-quantile plots. We present two examples from a data set of speech and gesture interactions, which illustrate the limitations of linear and log-linear mixed models, as compared to Cox models. The linear models are not validated on our data, whereas Cox models are. Moreover, in the second example, the Cox model exhibits a significant effect that the linear model does not. We provide methods to select the best-fitting models for repeated duration data and to compare statistical methodologies. In this study, we show that Cox models are best suited to the analysis of our data set.

Implications of path tolerance and path characteristics on critical vehicle manoeuvres

NASA Astrophysics Data System (ADS)

Lundahl, K.; Frisk, E.; Nielsen, L.

2017-12-01

Path planning and path following are core components in safe autonomous driving. Typically, a path planner provides a path with some tolerance on how tightly the path should be followed. Based on that, and other path characteristics, for example, sharpness of curves, a speed profile needs to be assigned so that the vehicle can stay within the given tolerance without going unnecessarily slow. Here, such trajectory planning is based on optimal control formulations where critical cases arise as on-the-limit solutions. The study focuses on heavy commercial vehicles, causing rollover to be of a major concern, due to the relatively high centre of gravity. Several results are obtained on required model complexity depending on path characteristics, for example, quantification of required path tolerance for a simple model to be sufficient, quantification of when yaw inertia needs to be considered in more detail, and how the curvature rate of change interplays with available friction. Overall, in situations where the vehicle is subject to a wide range of driving conditions, from good transport roads to more tricky avoidance manoeuvres, the requirements on the path following will vary. For this, the provided results form a basis for real-time path following.

Mixed messages in learning communication skills? Students comparing role model behaviour in clerkships with formal training.

PubMed

Essers, Geurt; Van Weel-Baumgarten, Evelyn; Bolhuis, Sanneke

2012-01-01

Medical students learn professional communication through formal training and in clinical practice. Physicians working in clinical practice have a powerful influence on student learning. However, they may demonstrate communication behaviours not aligning with recommendations in training programs. This study aims to identify more precisely what differences students perceive between role model communication behaviour during clerkships and formal training. In a cross-sectional study, data were collected about physicians' communication performance as perceived by students. Students filled out a questionnaire in four different clerkships in their fourth and fifth year. Just over half of the students reported communication similar to formal training. This was especially true for students in the later clerkships (paediatrics and primary care). Good examples were seen in providing information corresponding to patients' needs and in shared decision making, although students often noted that in fact the doctor made the decision. Bad examples were observed in exploring cognitions and emotions, and in providing information meeting patient's pace. Further study is needed on actual physician behaviour in clinical practice. From our results, we conclude that students need help in reflecting on and learning from the gap in communication patterns they observe in training versus clinical practice.

Quinoline Fluorescent Probes for Zinc - from Diagnostic to Therapeutic Molecules in Treating Neurodegenerative Diseases.

PubMed

Czaplinska, Barbara; Spaczynska, Ewelina; Musiol, Robert

2018-01-01

Fluorescent compounds had gained strong attention due to their wide and appealing applications. Microscopic techniques and visualization are good examples among others. Introduction of fluorescent dyes into microbiology opens the possibility to observe tissues, organisms or organelle with exceptional sensitivity and resolution. Probes for detection of biologically relevant metals as zinc, iron or copper seems to be particularly important for drug design and pharmaceutical sciences. Quinoline derivatives are well known for their good metal affinity and wide spectrum of biological activity. In this regard, molecular sensors built on this scaffold may be useful not only as analytical but also as therapeutic agents. In the present review, application of quinoline moiety in designing of novel fluorescent probes for zinc is presented and discussed. Zinc cations are relevant for vast majority of processes and recently attract a great deal of attention for their role in neurodegenerative diseases. Compounds interacting with Zn2+ may be used for early diagnosis of such disorders, for example the Alzheimer disease. Quinoline-based zinc probes may exert some beneficial role in organism acting as theranostic agents. First preliminary drugs for Alzheimer therapy that are based on quinoline moiety are good example of this trend. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Singing in Primary Schools: Case Studies of Good Practice in Whole Class Vocal Tuition

ERIC Educational Resources Information Center

Lamont, Alexandra; Daubney, Alison; Spruce, Gary

2012-01-01

Within the context of British initiatives in music education such as the Wider Opportunities programme in England and the recommendations of the Music Manifesto emphasising the importance of singing in primary schools, the current paper explores examples of good practice in whole-class vocal tuition. The research included seven different primary…

24 CFR 5.703 - Physical condition standards for HUD housing that is decent, safe, sanitary and in good repair...

Code of Federal Regulations, 2011 CFR

2011-04-01

... components, such as fencing and retaining walls, grounds, lighting, mailboxes/project signs, parking lots... exterior. Each building on the site must be structurally sound, secure, habitable, and in good repair. Each... source of potable water (note for example that single room occupancy units need not contain water...

Reconsidering Happiness in the Context of Social Justice Education

ERIC Educational Resources Information Center

Jackson, Liz; Bingham, Charles

2018-01-01

That happiness leads to lack of harm and suffering, representing both a good and a means to good, is promoted, for example, by educational philosophers such as Nel Noddings. But happiness should not be seen as an unproblematic goal, for education or otherwise. In this article, we critically investigate the importance of happiness in the…

29 CFR 779.207 - Related activities in retail operations.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Sess. p. 41.) For example, in operations of a single retailing business a drug store may sell a large variety of different products, and a grocery store may sell clothing and furniture and other goods... store are “related activities,” even if the store sells a great variety of different types of goods and...

29 CFR 779.207 - Related activities in retail operations.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Sess. p. 41.) For example, in operations of a single retailing business a drug store may sell a large variety of different products, and a grocery store may sell clothing and furniture and other goods... store are “related activities,” even if the store sells a great variety of different types of goods and...

29 CFR 779.207 - Related activities in retail operations.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Sess. p. 41.) For example, in operations of a single retailing business a drug store may sell a large variety of different products, and a grocery store may sell clothing and furniture and other goods... store are “related activities,” even if the store sells a great variety of different types of goods and...

29 CFR 779.207 - Related activities in retail operations.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Sess. p. 41.) For example, in operations of a single retailing business a drug store may sell a large variety of different products, and a grocery store may sell clothing and furniture and other goods... store are “related activities,” even if the store sells a great variety of different types of goods and...

29 CFR 779.207 - Related activities in retail operations.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Sess. p. 41.) For example, in operations of a single retailing business a drug store may sell a large variety of different products, and a grocery store may sell clothing and furniture and other goods... store are “related activities,” even if the store sells a great variety of different types of goods and...

29 CFR 779.348 - Goods must be made at the establishment which sells them.

Code of Federal Regulations, 2014 CFR

2014-07-01

... not be exempt. The latter is a manufacturing establishment. For example, a candy kitchen manufacturing candy for sale at separate retail outlets is a manufacturing establishment and not a retail... goods for sale to customers who will go to other places to buy them. Thus an establishment that makes or...

29 CFR 779.348 - Goods must be made at the establishment which sells them.

Code of Federal Regulations, 2013 CFR

2013-07-01

... not be exempt. The latter is a manufacturing establishment. For example, a candy kitchen manufacturing candy for sale at separate retail outlets is a manufacturing establishment and not a retail... goods for sale to customers who will go to other places to buy them. Thus an establishment that makes or...

29 CFR 779.348 - Goods must be made at the establishment which sells them.

Code of Federal Regulations, 2012 CFR

2012-07-01

... not be exempt. The latter is a manufacturing establishment. For example, a candy kitchen manufacturing candy for sale at separate retail outlets is a manufacturing establishment and not a retail... goods for sale to customers who will go to other places to buy them. Thus an establishment that makes or...

"Echo attributions" and other risks when publishing on novel therapies without peer review.

PubMed

Rosen, G M; Davison, G C

2001-10-01

A special series on Thought Field Therapy in the Journal of Clinical Psychology provides an opportunity for psychologists to learn about techniques and theories outside the mainstream of our field. Unfortunately, by publishing this series of manuscripts without meeting the standards of peer review, the Journal also provides an avenue for the misuse of its good reputation and the improper promotion of untested methods. "Echo attributions" can be made whereby an author attributes the source of his own words to the professional journal in which the text appears. Historical examples illustrate that such misuse of scientific journals and institutions occurs. A formal statement of guidelines is needed to instruct authors on appropriate versus unethical representations of their publications. Copyright 2001 John Wiley & Sons, Inc.

Using an employee handbook to head off problems.

PubMed

Hills, Laura Sachs

2005-01-01

Most medical practices agree that an employee handbook is a great idea. Many, however, don't know how to write a good handbook. This article provides a helpful overview of the kinds of materials that should and should not be included in your practice's employee handbook. It explores the many benefits of employee handbooks and identifies four policy topics that you should avoid. It suggests the benefits and potential uses of a glossary in your employee handbook and provides an example of the terms that might be included in a medical practice glossary. This article also suggests the appropriate language and tone for employee handbooks and offers advice about distributing them so your staff will read and understand your personnel policies. Finally, the article offers a blueprint for creating your own employee handbook.

Automated design and optimization of flexible booster autopilots via linear programming, volume 1

NASA Technical Reports Server (NTRS)

Hauser, F. D.

1972-01-01

A nonlinear programming technique was developed for the automated design and optimization of autopilots for large flexible launch vehicles. This technique, which resulted in the COEBRA program, uses the iterative application of linear programming. The method deals directly with the three main requirements of booster autopilot design: to provide (1) good response to guidance commands; (2) response to external disturbances (e.g. wind) to minimize structural bending moment loads and trajectory dispersions; and (3) stability with specified tolerances on the vehicle and flight control system parameters. The method is applicable to very high order systems (30th and greater per flight condition). Examples are provided that demonstrate the successful application of the employed algorithm to the design of autopilots for both single and multiple flight conditions.

Northeast Artificial Intelligence Consortium (NAIC). Volume 3. The Versatile Maintenance Expert System (VMES)

DTIC Science & Technology

1990-12-01

expected values. However, because the same good /bad output pattern of a device always gives rise to the same initial ordering, the method has its limitation...For any device and good /bad output pattern, it is easy to come up with an example on which the method does poorly in the sense that the actual...submodule is hss likely to be faulty if it is connec d to more good primary outputs. Initially, candidates are ordered according to their relat -nships with

Good Exemplars of Natural Scene Categories Elicit Clearer Patterns than Bad Exemplars but Not Greater BOLD Activity

PubMed Central

Torralbo, Ana; Walther, Dirk B.; Chai, Barry; Caddigan, Eamon; Fei-Fei, Li; Beck, Diane M.

2013-01-01

Within the range of images that we might categorize as a “beach”, for example, some will be more representative of that category than others. Here we first confirmed that humans could categorize “good” exemplars better than “bad” exemplars of six scene categories and then explored whether brain regions previously implicated in natural scene categorization showed a similar sensitivity to how well an image exemplifies a category. In a behavioral experiment participants were more accurate and faster at categorizing good than bad exemplars of natural scenes. In an fMRI experiment participants passively viewed blocks of good or bad exemplars from the same six categories. A multi-voxel pattern classifier trained to discriminate among category blocks showed higher decoding accuracy for good than bad exemplars in the PPA, RSC and V1. This difference in decoding accuracy cannot be explained by differences in overall BOLD signal, as average BOLD activity was either equivalent or higher for bad than good scenes in these areas. These results provide further evidence that V1, RSC and the PPA not only contain information relevant for natural scene categorization, but their activity patterns mirror the fundamentally graded nature of human categories. Analysis of the image statistics of our good and bad exemplars shows that variability in low-level features and image structure is higher among bad than good exemplars. A simulation of our neuroimaging experiment suggests that such a difference in variance could account for the observed differences in decoding accuracy. These results are consistent with both low-level models of scene categorization and models that build categories around a prototype. PMID:23555588

Subcutaneous injections: preventing needlestick injuries in the community.

PubMed

Aziz, Ann-Marie

2012-06-01

Community nurses provide care to patients in a variety of settings, for example health centres, community hospitals, patients' homes, residential and nursing homes. Administering subcutaneous injections to patients in the community is an everyday activity for many nurses in clinical practice. Many problems related to being 'sharps safe' are common to both community nurses and hospital staff. The majority of subcutaneous injections administered in the community are for patients with diabetes. Reducing needlestick injuries after the administration of subcutaneous injections in the community remains paramount to all NHS staff. This article provides information on what national standards to employ when administrating subcutaneous injections and what safety practices should be undertaken for good sharps management. Staff administering subcutaneous injections in the community need to ensure that they are updated on the latest developments in safety needle devices in order to prevent needlestick injuries and provide safe, effective and individualised care for their patients.

Training in Good Psychiatric Management for Borderline Personality Disorder in Residency: An Aide to Learning Supportive Psychotherapy for Challenging-to-Treat Patients.

PubMed

Bernanke, Joel; McCommon, Benjamin

2018-01-01

Given many competing demands, psychotherapy training to competency is difficult during psychiatric residency. Good Psychiatric Management for borderline personality disorder (GPM) offers an evidence-based, simplified, psychodynamically informed framework for the outpatient management of patients with borderline personality disorder, one of the most challenging disorders psychiatric residents must learn to treat. In this article, we provide an overview of GPM, and show that training in GPM meets a requirement for training in supportive psychotherapy; builds on psychodynamic psychotherapy training; and applies to other severe personality disorders, especially narcissistic personality disorder. We describe the interpersonal hypersensitivity model used in GPM as a straightforward way for clinicians to collaborate with patients in organizing approaches to psychoeducation, treatment goals, case management, use of multiple treatment modalities, and safety. A modification of the interpersonal hypersensitivity model that includes intra-personal hypersensitivity can be used to address narcissistic problems often present in borderline personality disorder. We argue that these features make GPM ideally suited for psychiatry residents in treating their most challenging patients, provide clinical examples to illustrate these points, and report the key lessons learned by a psychiatry resident after a year of GPM supervision.

Kin keepers and good providers: influence of gender socialization on well-being among USA birth cohorts.

PubMed

Salari, S; Zhang, W

2006-09-01

Previous research has suggested happiness and distress differ for men and women over the life course, but little attention has focused on whether the predictors of well-being vary for each group. The second wave of the National Survey of Families and Households (NSFH2) data was used to study whether hypothesized differential exposure to traditional gender socialization has influenced perceptions of life achievement, global happiness and depression for adult men and women in distinct USA birth cohorts. Numerous findings illustrated similarity among cohort and gender groups in predictors of well-being. There was also evidence of a change in USA gender socialization, and determinants of the dependent variables varied according to these shifts by sex and cohort membership. For example, in the earliest born cohort, women's happiness was related to frequency of contact with relatives, consistent with the kin keeper role. Assets and income predicted depression and global happiness for older men, suggesting a link between well-being and the good provider role. In the latest born cohorts, not just androgynous, but opposite influences predominated as men and women demonstrated less evidence of traditional socialization shaping their satisfaction with achievements and psychological well-being.

Reporting recommendations for tumor marker prognostic studies (REMARK): explanation and elaboration

PubMed Central

2012-01-01

Background The Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK) checklist consists of 20 items to report for published tumor marker prognostic studies. It was developed to address widespread deficiencies in the reporting of such studies. In this paper we expand on the REMARK checklist to enhance its use and effectiveness through better understanding of the intent of each item and why the information is important to report. Methods REMARK recommends including a transparent and full description of research goals and hypotheses, subject selection, specimen and assay considerations, marker measurement methods, statistical design and analysis, and study results. Each checklist item is explained and accompanied by published examples of good reporting, and relevant empirical evidence of the quality of reporting. We give prominence to discussion of the 'REMARK profile', a suggested tabular format for summarizing key study details. Summary The paper provides a comprehensive overview to educate on good reporting and provide a valuable reference for the many issues to consider when designing, conducting, and analyzing tumor marker studies and prognostic studies in medicine in general. To encourage dissemination of the Reporting Recommendations for Tumor Marker Prognostic Studies (REMARK): Explanation and Elaboration, this article has also been published in PLoS Medicine. PMID:22642691

Can an employer-based health insurance system be just?

PubMed

Jecker, N S

1993-01-01

It is America's distinctive practice to tie private health insurance to employment, and recent proposals have tried to retain this link through mandating that all employers provide health insurance to their employees. My primary approach to these issues is neither economic, nor historical, nor political but ethical. After a brief historical overview, I outline a general approach to evaluating the ethical significance of linking the distributions of distinct goods. I examine whether an unjust distribution of jobs spoils justice in the distribution of health insurance, taking as a central example gender inequities in employment and exploring their impact on job-based health insurance. Second, I explore the possibility that justly awarding jobs guarantees justice in employment-sponsored insurance. However, linking the distributions of different goods remains problematic, because such links inevitably undermine equality by enabling the same individuals to enjoy advantages in many different distributive areas. Finally, I examine recent proposals to reform America's health care system by requiring all employers to provide health insurance to their employees. I argue that such proposals lend themselves to the same ethical problems that the current system does and urge greater attention to alternative reform options.

Pipes, Petrol, Paint and Pewter: The Rise and Fall of Lead

ERIC Educational Resources Information Center

Peacock, Alan

2010-01-01

Lead is a good example of a metal that was used for many things over centuries--in water pipes, paints, on roofs, and in leaded petrol, for example--but was superseded as scientists discovered "new" metals, and because its toxicity became a problem. It was originally an important element in pewter utensils, alloyed with tin; it made the…

The nuts and bolts of evaluating science communication activities.

PubMed

Spicer, Suzanne

2017-10-01

Since 2008 there has been a focus on fostering a culture of public engagement in higher education plus an impact agenda that demands scientists provide evidence of how their work, including their science communication, is making a difference. Good science communication takes a significant amount of time to plan and deliver so how can you improve what you are doing and demonstrate if you are having an impact? The answer is to evaluate. Effective evaluation needs to be planned so this paper takes you step by step through the evaluation process, illustrated using specific examples. Crown Copyright © 2017. Published by Elsevier Ltd. All rights reserved.

Baseball Physics: A New Mechanics Lab

NASA Astrophysics Data System (ADS)

Wagoner, Kasey; Flanagan, Daniel

2018-05-01

The game of baseball provides an interesting laboratory for experimenting with mechanical phenomena (there are many good examples in The Physics Teacher, available on Professor Alan Nathan's website, and discussed in Physics of Baseball & Softball). We have developed a lab, for an introductory-level physics course, that investigates many of these phenomena. The lab uses inexpensive, readily available equipment such as wooden baseball bats, baseballs, and actual Major League Baseball data. By the end of the lab, students have revisited many concepts they learned earlier in the semester and come away with an understanding of how to put seemingly disparate ideas together to analyze a fun sport.

Spitzer Science operations: the good, the bad, and the ugly

NASA Astrophysics Data System (ADS)

Levine, Deborah A.

2008-07-01

We review the Spitzer Space Telescope Science Center operations teams and processes and their interfaces with other Project elements -- what we planned early in the development of the science center, what we had at a launch and what we have now and why. We also explore the checks and balances behind building an organizational structure that supports constructive airing of conflicts and a timely resolution that balances the inputs and provides for very efficient on-orbit operations. For example, what organizational roles are involved in reviewing observing schedules, what constituency do they represent and who has authority to approve or disapprove the schedule.

Yleaf: Software for Human Y-Chromosomal Haplogroup Inference from Next-Generation Sequencing Data.

PubMed

Ralf, Arwin; Montiel González, Diego; Zhong, Kaiyin; Kayser, Manfred

2018-05-01

Next-generation sequencing (NGS) technologies offer immense possibilities given the large genomic data they simultaneously deliver. The human Y-chromosome serves as good example how NGS benefits various applications in evolution, anthropology, genealogy, and forensics. Prior to NGS, the Y-chromosome phylogenetic tree consisted of a few hundred branches, based on NGS data, it now contains many thousands. The complexity of both, Y tree and NGS data provide challenges for haplogroup assignment. For effective analysis and interpretation of Y-chromosome NGS data, we present Yleaf, a publically available, automated, user-friendly software for high-resolution Y-chromosome haplogroup inference independently of library and sequencing methods.

Undifferentiated febrile illnesses in military personnel.

PubMed

Burns, Daniel S; Bailey, Mark S

2013-09-01

Undifferentiated febrile illnesses (UFIs) present with acute symptoms, objective fever and no specific organ focus on clinical assessment. The term is mostly used in developing and tropical countries where a wide range of infections may be responsible. Laboratory diagnosis often requires specialist microbiology investigations that are not widely available, and serology tests that only become positive during convalescence. Optimal clinical management requires a good travel history, awareness of local endemic diseases, an understanding of the features that may help distinguish different causes and appropriate use of empirical antibiotics. This review describes the most common examples of UFI in military personnel on overseas deployments, and provides a practical approach to their initial management.

Synopsis of timing measurement techniques used in telecommunications

NASA Technical Reports Server (NTRS)

Zampetti, George

1993-01-01

Historically, Maximum Time Interval Error (MTIE) and Maximum Relative Time Interval Error (MRTIE) have been the main measurement techniques used to characterize timing performance in telecommunications networks. Recently, a new measurement technique, Time Variance (TVAR) has gained acceptance in the North American (ANSI) standards body. TVAR was developed in concurrence with NIST to address certain inadequacies in the MTIE approach. The advantages and disadvantages of each of these approaches are described. Real measurement examples are presented to illustrate the critical issues in actual telecommunication applications. Finally, a new MTIE measurement is proposed (ZTIE) that complements TVAR. Together, TVAR and ZTIE provide a very good characterization of network timing.

Control of Flexible Systems in the Presence of Failures

NASA Technical Reports Server (NTRS)

Magahami, Peiman G.; Cox, David E.; Bauer, Frank H. (Technical Monitor)

2001-01-01

Control of flexible systems under degradation or failure of sensors/actuators is considered. A Linear Matrix Inequality framework is used to synthesize H(sub infinity)-based controllers, which provide good disturbance rejection while capable of tolerating real parameter uncertainties in the system model, as well as potential degradation or failure of the control system hardware. In this approach, a one-at-a-time failure scenario is considered, wherein no more than one sensor or actuator is allowed to fail at any given time. A numerical example involving control synthesis for a two-dimensional flexible system is presented to demonstrate the feasibility of the proposed approach.

Gamification and serious games for personalized health.

PubMed

McCallum, Simon

2012-01-01

Computer games are no longer just a trivial activity played by children in arcades. Social networking and casual gaming have broadened the market for, and acceptance of, games. This has coincided with a realization of their power to engage and motivate players. Good computer games are excellent examples of modern educational theory [1]. The military, health providers, governments, and educators, all use computer games. This paper focuses on Games for Health, discussing the range of areas and approaches to developing these games. We extend a taxonomy for Games for Health, describe a case study on games for dementia sufferers, and finally, present some challenges and research opportunities in this area.

Uncertainty Estimation Cheat Sheet for Probabilistic Risk Assessment

NASA Technical Reports Server (NTRS)

Britton, Paul T.; Al Hassan, Mohammad; Ring, Robert W.

2017-01-01

"Uncertainty analysis itself is uncertain, therefore, you cannot evaluate it exactly," Source Uncertain Quantitative results for aerospace engineering problems are influenced by many sources of uncertainty. Uncertainty analysis aims to make a technical contribution to decision-making through the quantification of uncertainties in the relevant variables as well as through the propagation of these uncertainties up to the result. Uncertainty can be thought of as a measure of the 'goodness' of a result and is typically represented as statistical dispersion. This paper will explain common measures of centrality and dispersion; and-with examples-will provide guidelines for how they may be estimated to ensure effective technical contributions to decision-making.

Lognormal Uncertainty Estimation for Failure Rates

NASA Technical Reports Server (NTRS)

Britton, Paul T.; Al Hassan, Mohammad; Ring, Robert W.

2017-01-01

"Uncertainty analysis itself is uncertain, therefore, you cannot evaluate it exactly," Source Uncertain. Quantitative results for aerospace engineering problems are influenced by many sources of uncertainty. Uncertainty analysis aims to make a technical contribution to decision-making through the quantification of uncertainties in the relevant variables as well as through the propagation of these uncertainties up to the result. Uncertainty can be thought of as a measure of the 'goodness' of a result and is typically represented as statistical dispersion. This presentation will explain common measures of centrality and dispersion; and-with examples-will provide guidelines for how they may be estimated to ensure effective technical contributions to decision-making.

Numerical modeling of pollutant transport using a Lagrangian marker particle technique

NASA Technical Reports Server (NTRS)

Spaulding, M.

1976-01-01

A derivation and code were developed for the three-dimensional mass transport equation, using a particle-in-cell solution technique, to solve coastal zone waste discharge problems where particles are a major component of the waste. Improvements in the particle movement techniques are suggested and typical examples illustrated. Preliminary model comparisons with analytic solutions for an instantaneous point release in a uniform flow show good results in resolving the waste motion. The findings to date indicate that this computational model will provide a useful technique to study the motion of sediment, dredged spoils, and other particulate waste commonly deposited in coastal waters.

Collaborative evaluation of a high school prevention curriculum: How methods of collaborative evaluation enhanced a randomized control trial to inform program improvement.

PubMed

Orsini, Muhsin Michael; Wyrick, David L; Milroy, Jeffrey J

2012-11-01

Blending high-quality and rigorous research with pure evaluation practice can often be best accomplished through thoughtful collaboration. The evaluation of a high school drug prevention program (All Stars Senior) is an example of how perceived competing purposes and methodologies can coexist to investigate formative and summative outcome variables that can be used for program improvement. Throughout this project there were many examples of client learning from evaluator and evaluator learning from client. This article presents convincing evidence that collaborative evaluation can improve the design, implementation, and findings of the randomized control trial. Throughout this paper, we discuss many examples of good science, good evaluation, and other practical benefits of practicing collaborative evaluation. Ultimately, the authors created the term pre-formative evaluation to describe the period prior to data collection and before program implementation, when collaborative evaluation can inform program improvement. Copyright © 2012 Elsevier Ltd. All rights reserved.

Piecewise-homotopy analysis method (P-HAM) for first order nonlinear ODE

NASA Astrophysics Data System (ADS)

Chin, F. Y.; Lem, K. H.; Chong, F. S.

2013-09-01

In homotopy analysis method (HAM), the determination for the value of the auxiliary parameter h is based on the valid region of the h-curve in which the horizontal segment of the h-curve will decide the valid h-region. All h-value taken from the valid region, provided that the order of deformation is large enough, will in principle yield an approximation series that converges to the exact solution. However it is found out that the h-value chosen within this valid region does not always promise a good approximation under finite order. This paper suggests an improved method called Piecewise-HAM (P-HAM). In stead of a single h-value, this method suggests using many h-values. Each of the h-values comes from an individual h-curve while each h-curve is plotted by fixing the time t at a different value. Each h-value is claimed to produce a good approximation only about a neighborhood centered at the corresponding t which the h-curve is based on. Each segment of these good approximations is then joined to form the approximation curve. By this, the convergence region is enhanced further. The P-HAM is illustrated and supported by examples.

How to establish a first-class international scientific journal in China?

PubMed

Li, Zhen-Xi

2006-11-21

Hundreds of scientific journals are published in China. However, only scores of them are included in Science Citation Index by the Institute for Scientific Information, with impact factors of only 1 or less. Thus, how to establish a first-class international scientific journal in China is an important but difficult topic that deserves extensive exploration. World Journal of Gastroenterology (WJG) sets a good example although it has experienced setbacks on the road towards success. Concepts and pursuits that affirm the overall development direction, innovation and dreams that provide impetus and aspiration for higher objectives, team work and unique pattern that assure excellent quality and service, and culture and environment that also determine the speed and direction of the development, are believed to be the major factors contributing to the success of WJG. It is recommended that the effective resolution to the above issue is to learn from Chinese examples such as WJG rather than from "how foreign journals do".

Seriously Implementing Health Capacity Strengthening Programs in Africa: Comment on "Implementation of a Health Management Mentoring Program: Year-1 Evaluation of Its Impact on Health System Strengthening in Zambézia Province, Mozambique".

PubMed

Lapão, Luís Velez

2015-07-14

Faced with the challenges of healthcare reform, skills and new capabilities are needed to support the reform and it is of crucial importance in Africa where shortages affects the health system resilience. Edwards et al provides a good example of the challenge of implementing a mentoring program in one province in a sub-Saharan country. From this example, various aspects of strengthening the capacity of managers in healthcare are examined based on our experience in action-training in Africa, as mentoring shares many characteristics with action-training. What practical lessons can be drawn to promote the strengthening so that managers can better intervene in complex contexts? Deeper involvement of health authorities and more rigorous approaches are seriously desirable for the proper development of health capacity strengthening programs in Africa. © 2015 by Kerman University of Medical Sciences.

Examples of Mathematical Modeling

PubMed Central

Johnston, Matthew D.; Edwards, Carina M.; Bodmer, Walter F.; Maini, Philip K.; Chapman, S. Jonathan

2008-01-01

Mathematical modeling is being increasingly recognized within the biomedical sciences as an important tool that can aid the understanding of biological systems. The heavily regulated cell renewal cycle in the colonic crypt provides a good example of how modeling can be used to find out key features of the system kinetics, and help to explain both the breakdown of homeostasis and the initiation of tumorigenesis. We use the cell population model by Johnston et al.5 to illustrate the power of mathematical modeling by considering two key questions about the cell population dynamics in the colonic crypt. We ask: how can a model describe both homeostasis and unregulated growth in tumorigenesis; and to which parameters in the system is the model most sensitive? In order to address these questions, we discuss what type of modeling approach is most appropriate in the crypt. We use the model to argue why tumorigenesis is observed to occur in stages with long lag phases between periods of rapid growth, and we identify the key parameters. PMID:17873520

Choice theories: What are they good for?☆

PubMed Central

Johnson, Eric J.

2013-01-01

Simonson et al. present an ambitious sketch of an integrative theory of context. Provoked by this thoughtful proposal, I discuss what is the function of theories of choice in the coming decades. Traditionally, choice models and theory have attempted to predict choices as a function of the attributes of options. I argue that to be truly useful, they need to generate specific and quantitative predictions of the effect of the choice environment upon choice probability. To do this, we need to focus on rigorously modeling and measuring the underlying processes causing these effects, and use the Simonson et al. proposal to provide some examples. I also present some examples from research in decision-making and decision neuroscience, and argue that models that fail, and fail spectacularly are particularly useful. I close with a challenge: How would consumer researcher aid the design of real world choice environments such as the health exchanges under the Patient Protection and Affordable Care Act? PMID:23794793

How to establish a first-class international scientific journal in China?

PubMed Central

Li, Zhen-Xi

2006-01-01

Hundreds of scientific journals are published in China. However, only scores of them are included in Science Citation Index by the Institute for Scientific Information, with impact factors of only 1 or less. Thus, how to establish a first-class international scientific journal in China is an important but difficult topic that deserves extensive exploration. World Journal of Gastroenterology (WJG) sets a good example although it has experienced setbacks on the road towards success. Concepts and pursuits that affirm the overall development direction, innovation and dreams that provide impetus and aspiration for higher objectives, team work and unique pattern that assure excellent quality and service, and culture and environment that also determine the speed and direction of the development, are believed to be the major factors contributing to the success of WJG. It is recommended that the effective resolution to the above issue is to learn from Chinese examples such as WJG rather than from “how foreign journals do”. PMID:17109509

Mesh refinement in finite element analysis by minimization of the stiffness matrix trace

NASA Technical Reports Server (NTRS)

Kittur, Madan G.; Huston, Ronald L.

1989-01-01

Most finite element packages provide means to generate meshes automatically. However, the user is usually confronted with the problem of not knowing whether the mesh generated is appropriate for the problem at hand. Since the accuracy of the finite element results is mesh dependent, mesh selection forms a very important step in the analysis. Indeed, in accurate analyses, meshes need to be refined or rezoned until the solution converges to a value so that the error is below a predetermined tolerance. A-posteriori methods use error indicators, developed by using the theory of interpolation and approximation theory, for mesh refinements. Some use other criterions, such as strain energy density variation and stress contours for example, to obtain near optimal meshes. Although these methods are adaptive, they are expensive. Alternatively, a priori methods, until now available, use geometrical parameters, for example, element aspect ratio. Therefore, they are not adaptive by nature. An adaptive a-priori method is developed. The criterion is that the minimization of the trace of the stiffness matrix with respect to the nodal coordinates, leads to a minimization of the potential energy, and as a consequence provide a good starting mesh. In a few examples the method is shown to provide the optimal mesh. The method is also shown to be relatively simple and amenable to development of computer algorithms. When the procedure is used in conjunction with a-posteriori methods of grid refinement, it is shown that fewer refinement iterations and fewer degrees of freedom are required for convergence as opposed to when the procedure is not used. The mesh obtained is shown to have uniform distribution of stiffness among the nodes and elements which, as a consequence, leads to uniform error distribution. Thus the mesh obtained meets the optimality criterion of uniform error distribution.

On optimal soft-decision demodulation

NASA Technical Reports Server (NTRS)

Lee, L. N.

1975-01-01

Wozencraft and Kennedy have suggested that the appropriate demodulator criterion of goodness is the cut-off rate of the discrete memoryless channel created by the modulation system; the criterion of goodness adopted in this note is the symmetric cut-off rate which differs from the former criterion only in that the signals are assumed equally likely. Massey's necessary condition for optimal demodulation of binary signals is generalized to M-ary signals. It is shown that the optimal demodulator decision regions in likelihood space are bounded by hyperplanes. An iterative method is formulated for finding these optimal decision regions from an initial good quess. For additive white Gaussian noise, the corresponding optimal decision regions in signal space are bounded by hypersurfaces with hyperplane asymptotes; these asymptotes themselves bound the decision regions of a demodulator which, in several examples, is shown to be virtually optimal. In many cases, the necessary condition for demodulator optimality is also sufficient, but a counter example to its general sufficiency is given.

Toward defining good writing: A rhetorical analysis of the words, sentences, and paragraphs in 16 industrial scripts

NASA Technical Reports Server (NTRS)

Freisinger, R. R.; Petersen, B. T.

1981-01-01

The assumption that teachers of technical writing agree on a definition of good writing was found to be without basis. Resolution of disagreements arising from close reading and textual analysis is described. Writing samples from corporate sources including IBM, ALCOA, Exxon, Weyerhaeuser, Bell Labs, Underwriters Laboratories, Dow Chemical, and US Steel were requested. A mixture of informative and persuasive examples, and examples directed at lay and specialist audiences were received. Analyses of 16 writing samples are reported. Analysis of word level, sentence level, and paragraph level, was completed. Syllabism, verb selection, nominalizations, vocabulary choices, t-units, subordination, sentence and clause length, syntactic order, patterns, development, topic sentences, propositional order, and transitions were analyzed.

The current state and developments in higher education in gerontology in the nordic countries.

PubMed

Hietanen, Heidi; Lyyra, Tiina-Mari; Parkatti, Terttu; Heikkinen, Eino

2012-01-01

The growing size of the older population challenges not only researchers but also higher education in gerontology. On the basis of an online survey the authors describe the situation of Nordic higher education in gerontology in 2008 and 2009 and also give some good examples of Nordic- and European-level collaboration. The survey results showed that gerontological education was given in every Nordic country, in 31 universities and 60 other higher education institutions. Although separate aging-related courses and modules were relatively numerous, programs for majors were relatively few. Networking in the Nordic region offers a good example on how to further develop higher education in gerontology. Emphasis should be put on strengthening networking on the European and trans-Atlantic levels.

Creating Environments that Sustain Children, Staff, and Our Planet

ERIC Educational Resources Information Center

Stoecklin, Vicki L.

2005-01-01

Early childhood educators know that a child's values are formed before age five, yet they have done little to teach young children how to be good stewards of the earth. This article discusses what early childhood practitioners can do to set a good example for children by demonstrating ways to be more in tune with Mother Earth. The author states…

Conquering Fear: The Role of Fantasy and Horror Fiction in the Classroom.

ERIC Educational Resources Information Center

Compora, Daniel P.

Many English teachers face the widespread misconception that if a work of fiction is enjoyable, it cannot be good, or, conversely, if it is good, it cannot be enjoyable. Critics of horror fiction, for example, would likely argue that better reading materials are available for students to read. Inclusion of materials other than "classics" into the…

What Is Music Good For? A Dialogue on Technical and Ritual Rationality

ERIC Educational Resources Information Center

Røyseng, Sigrid; Varkøy, Øivind

2014-01-01

In different ways and in different contexts it has been and still is argued that music education should be prioritized because of its positive impact on pupils in terms of general development as good citizens and in terms of skills in other disciplines. In this article, the authors discuss whether this tendency is best interpreted as an example of…

20 CFR 416.554 - Waiver of adjustment or recovery-against equity and good conscience.

Code of Federal Regulations, 2010 CFR

2010-04-01

... eligible couple that is legally separated and/or living apart for that part of an overpayment not received... subsequently found that the money was improperly paid. Recovery would be considered “against equity and good conscience.” Example 3: Mr. and Mrs. Smith—members of an eligible couple—separate in July. Later in July, Mr...

Are Key Principles for improved health technology assessment supported and used by health technology assessment organizations?

PubMed

Neumann, Peter J; Drummond, Michael F; Jönsson, Bengt; Luce, Bryan R; Schwartz, J Sanford; Siebert, Uwe; Sullivan, Sean D

2010-01-01

Previously, our group-the International Working Group for HTA Advancement-proposed a set of fifteen Key Principles that could be applied to health technology assessment (HTA) programs in different jurisdictions and across a range of organizations and perspectives. In this commentary, we investigate the extent to which these principles are supported and used by fourteen selected HTA organizations worldwide. We find that some principles are broadly supported: examples include being explicit about HTA goals and scope; considering a wide range of evidence and outcomes; and being unbiased and transparent. Other principles receive less widespread support: examples are addressing issues of generalizability and transferability; being transparent on the link between HTA findings and decision-making processes; considering a full societal perspective; and monitoring the implementation of HTA findings. The analysis also suggests a lack of consensus in the field about some principles--for example, considering a societal perspective. Our study highlights differences in the uptake of key principles for HTA and indicates considerable room for improvement for HTA organizations to adopt principles identified to reflect good HTA practices. Most HTA organizations espouse certain general concepts of good practice--for example, assessments should be unbiased and transparent. However, principles that require more intensive follow-up--for example, monitoring the implementation of HTA findings--have received little support and execution.

Use of digital technologies for nasal prosthesis manufacturing.

PubMed

Palousek, David; Rosicky, Jiri; Koutny, Daniel

2014-04-01

Digital technology is becoming more accessible for common use in medical applications; however, their expansion in prosthetic and orthotic laboratories is not large because of the persistent image of difficult applicability to real patients. This article aims to offer real example in the area of human facial prostheses. This article describes the utilization of optical digitization, computational modelling, rapid prototyping, mould fabrication and manufacturing of a nasal silicone prosthesis. This technical note defines the key points of the methodology and aspires to contribute to the introduction of a certified manufacturing procedure. The results show that the used technologies reduce the manufacturing time, reflect patient's requirements and allow the manufacture of high-quality prostheses for missing facial asymmetric parts. The methodology provides a good position for further development issues and is usable for clinical practice. Clinical relevance Utilization of digital technologies in facial prosthesis manufacturing process can be a good contribution for higher patient comfort and higher production efficiency but with higher initial investment and demands for experience with software tools.

Economic game theory for mutualism and cooperation.

PubMed

Archetti, Marco; Scheuring, István; Hoffman, Moshe; Frederickson, Megan E; Pierce, Naomi E; Yu, Douglas W

2011-12-01

We review recent work at the interface of economic game theory and evolutionary biology that provides new insights into the evolution of partner choice, host sanctions, partner fidelity feedback and public goods. (1) The theory of games with asymmetrical information shows that the right incentives allow hosts to screen-out parasites and screen-in mutualists, explaining successful partner choice in the absence of signalling. Applications range from ant-plants to microbiomes. (2) Contract theory distinguishes two longstanding but weakly differentiated explanations of host response to defectors: host sanctions and partner fidelity feedback. Host traits that selectively punish misbehaving symbionts are parsimoniously interpreted as pre-adaptations. Yucca-moth and legume-rhizobia mutualisms are argued to be examples of partner fidelity feedback. (3) The theory of public goods shows that cooperation in multi-player interactions can evolve in the absence of assortment, in one-shot social dilemmas among non-kin. Applications include alarm calls in vertebrates and exoenzymes in microbes. 2011 Blackwell Publishing Ltd/CNRS.

ACE forum report: the making of an epidemiologist--necessary components for doctoral education and training.

PubMed

Lee, Nora L; Samet, Jonathan M

2003-09-01

The 2002 meeting of the American College of Epidemiology included an open forum on doctoral education and training in epidemiology. Discussion groups, facilitated by selected senior epidemiologists, recommended changes that would better prepare future epidemiologists to meet new challenges in public health and to build successful careers. The forum discussions were complemented by a panel of two doctoral students and two senior epidemiologists who provided their perspectives on each of the topics. Within discussion groups, agreement was clear on some issues and elusive on others. For example, good mentoring was considered a critical factor for a successful career, but how good mentoring can be promoted was a more complex issue. Likewise, experience with primary data collection should be a standard requirement for the doctoral degree, but the group's definition of primary data collection was more ambiguous. The recommendations derived from the education forum are summarized in this report, which may serve as an impetus for changes in the education and training of future epidemiologists.

Rapid detection of atrazine and metolachlor in farm soils: gas chromatography-mass spectrometry-based analysis using the bubble-in-drop single drop microextraction enrichment method.

PubMed

Williams, D Bradley G; George, Mosotho J; Marjanovic, Ljiljana

2014-08-06

Tracking of metolachlor and atrazine herbicides in agricultural soils, from spraying through to harvest, was conducted using our recently reported "bubble-in-drop single-drop microextraction" method. The method showed good linearity (R(2) = 0.999 and 0.999) in the concentration range of 0.01-1.0 ng/mL with LOD values of 0.01 and 0.02 ng/mL for atrazine and metolachlor, respectively. Sonication methods were poor at releasing these herbicides from the soil matrixes, while hot water extraction readily liberated them, providing an efficient accessible alternative to sonication techniques. Good recoveries of 97% and 105% were shown for atrazine and metolachlor, respectively, from the soil. The spiking protocol was also investigated, resulting in a traceless spiking method. We demonstrate a very sensitive technique by which to assess, for example, the length of residence of pesticides in given soils and thus risk of exposure.

PUMAS (Practical Uses of Math And Science) - Low Cost, High Impact

NASA Astrophysics Data System (ADS)

Kahn, R. A.

2004-12-01

PUMAS is an on-line journal, aimed at giving pre-college teachers brief examples showing how math and science topics taught in K-12 classes can be used in interesting settings, including everyday life. The concept is a simple one - (1) ask scientists, engineers, and other content experts to write up their favorite examples of practical uses, (2) ask the authors to key their examples to the National Standards and Benchmarks, so the material is grade-appropriate and useful in the classroom, (3) have each example peer-reviewed by at least one scientist with a relevant background, and at least one teacher at an appropriate grade level, helping keep an emphasis on quality, and (4) disseminate the examples widely and inexpensively through the PUMAS Web Site (http://pumas.jpl.nasa.gov). PUMAS examples may be activities, anecdotes, descriptions of "neat ideas," formal exercises, puzzles, or demonstrations; each one is a gem, written in the voice of its author. The PUMAS site also provides opportunities for feedback on individual examples and on the journal as a whole. As with most scientific journals, the writing, reviewing, and editing efforts are volunteered; they leverage the "community service" offered by so many teachers and scientists. We have streamlined all aspects of the example submission, review, and search processes so participants can contribute at a high level, with a minimum of extraneous effort. The primary PUMAS operating expenses cover Web Site technical maintenance and computer security. The PUMAS site receives several thousand unique queries per week, and publishes an average of about one new example per month. Maintaining a strong user base has been helped by endorsements from such organizations as the NSTA and NCTM. To contributors we offer an avenue for making a real impact on pre-college education with a relatively small time commitment, and the opportunity for peer-reviewed publication. We are always looking for good examples of the Practical Uses of Math And Science. This work is performed at the Jet Propulsion Laboratory, California Institute of Technology, under contract with the National Aeronautics and Space Administration.

Finite element method formulation in polar coordinates for transient heat conduction problems

NASA Astrophysics Data System (ADS)

Duda, Piotr

2016-04-01

The aim of this paper is the formulation of the finite element method in polar coordinates to solve transient heat conduction problems. It is hard to find in the literature a formulation of the finite element method (FEM) in polar or cylindrical coordinates for the solution of heat transfer problems. This document shows how to apply the most often used boundary conditions. The global equation system is solved by the Crank-Nicolson method. The proposed algorithm is verified in three numerical tests. In the first example, the obtained transient temperature distribution is compared with the temperature obtained from the presented analytical solution. In the second numerical example, the variable boundary condition is assumed. In the last numerical example the component with the shape different than cylindrical is used. All examples show that the introduction of the polar coordinate system gives better results than in the Cartesian coordinate system. The finite element method formulation in polar coordinates is valuable since it provides a higher accuracy of the calculations without compacting the mesh in cylindrical or similar to tubular components. The proposed method can be applied for circular elements such as boiler drums, outlet headers, flux tubes. This algorithm can be useful during the solution of inverse problems, which do not allow for high density grid. This method can calculate the temperature distribution in the bodies of different properties in the circumferential and the radial direction. The presented algorithm can be developed for other coordinate systems. The examples demonstrate a good accuracy and stability of the proposed method.

12 CFR 366.11 - Will the FDIC waive a conflict of interest?

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Will the FDIC waive a conflict of interest? 366... FDIC waive a conflict of interest? (a) We may waive a conflict of interest for good cause shown at our... examples of when we may grant you a waiver for a conflict of interest. These examples are not inclusive. (1...

Red River chloride remote sensing study

NASA Technical Reports Server (NTRS)

1975-01-01

Side looking radar, infrared thermal imagery and color photography, together with a few examples of black and white panoramic photos, are used to supplement information on the natural saline pollution problem that is hydrologically and geologically oriented. The study area was explored concurrently by ground methods and a reasonably good understanding of hydrogeological conditions has been achieved. Examples of the products acquired, their interpretation, and use techniques are included.

Parametrizing growth in dark energy and modified gravity models

NASA Astrophysics Data System (ADS)

Resco, Miguel Aparicio; Maroto, Antonio L.

2018-02-01

It is well known that an extremely accurate parametrization of the growth function of matter density perturbations in Λ CDM cosmology, with errors below 0.25%, is given by f (a )=Ωmγ(a ) with γ ≃0.55 . In this work, we show that a simple modification of this expression also provides a good description of growth in modified gravity theories. We consider the model-independent approach to modified gravity in terms of an effective Newton constant written as μ (a ,k )=Geff/G and show that f (a )=β (a )Ωmγ(a ) provides fits to the numerical solutions with similar accuracy to that of Λ CDM . In the time-independent case with μ =μ (k ), simple analytic expressions for β (μ ) and γ (μ ) are presented. In the time-dependent (but scale-independent) case μ =μ (a ), we show that β (a ) has the same time dependence as μ (a ). As an example, explicit formulas are provided in the Dvali-Gabadadze-Porrati (DGP) model. In the general case, for theories with μ (a ,k ), we obtain a perturbative expansion for β (μ ) around the general relativity case μ =1 which, for f (R ) theories, reaches an accuracy below 1%. Finally, as an example we apply the obtained fitting functions in order to forecast the precision with which future galaxy surveys will be able to measure the μ parameter.

Economic Valuation of Ecosystem Goods and Services in a Melting Arctic

NASA Astrophysics Data System (ADS)

O'Garra, T.

2014-12-01

The Arctic region is composed of unique ecosystems that provide a range of goods and services to local and global populations. However, Arctic sea-ice is melting at an unprecedented rate, threatening many of these ecosystems and the services they provide. Yet as the ice melts and certain goods and services are lost, other resources such as oil and minerals will become accessible. The question is: how do the losses compare with the opportunities? And how are the losses and potential gains likely to be distributed? To address these questions, this study provides a preliminary assessment of the quantity, distribution and economic value of the ecosystem services (ES) provided by Arctic ecosystems, both now and in the future given a scenario of sure climate change. Using biophysical and economic data from existing studies (and some primary data), preliminary estimates indicate that the Arctic currently provides 357m/yr (in 2014 US) in subsistence hunting value to local communities, of which reindeer/caribou comprise 83%. Reindeer herding provides 110m/yr to Arctic communities. Interestingly, 'non-use (existence/cultural) values' associated with Arctic species are very high at 11bn/yr to members of Arctic states. The Arctic also provides ES that accrue to the global community: oil resources (North Slope; 5bn profits in 2013), commercial fisheries ( 515mn/yr) and most importantly, climate regulation services. Recent models (Whiteman; Euskirchen) estimate that the loss of climate regulation services provided by Arctic ice will cost 200 - 500bn/yr, a value which dwarfs all others. Assuming no change in atmospheric temperature compared to 2014, the net present value of the Arctic by 2050 (1.4% discount rate) comes to over $9 trillion. However, given Wang and Overland (2009) predictions of ice-free summers by 2037, we expect many of these benefits will be lost. For example, it is fairly well-established that endemic species, such as polar bears, will decline with sea-ice melt. Estimation of such losses is ongoing for the present study. Increased opportunities include oil and mineral extraction, and increased shipping. The economic values associated with these potential opportunities (including environmental and social costs) are currently being assessed for the present study.

Quantifying the impact of time-varying baseline risk adjustment in the self-controlled risk interval design.

PubMed

Li, Lingling; Kulldorff, Martin; Russek-Cohen, Estelle; Kawai, Alison Tse; Hua, Wei

2015-12-01

The self-controlled risk interval design is commonly used to assess the association between an acute exposure and an adverse event of interest, implicitly adjusting for fixed, non-time-varying covariates. Explicit adjustment needs to be made for time-varying covariates, for example, age in young children. It can be performed via either a fixed or random adjustment. The random-adjustment approach can provide valid point and interval estimates but requires access to individual-level data for an unexposed baseline sample. The fixed-adjustment approach does not have this requirement and will provide a valid point estimate but may underestimate the variance. We conducted a comprehensive simulation study to evaluate their performance. We designed the simulation study using empirical data from the Food and Drug Administration-sponsored Mini-Sentinel Post-licensure Rapid Immunization Safety Monitoring Rotavirus Vaccines and Intussusception study in children 5-36.9 weeks of age. The time-varying confounder is age. We considered a variety of design parameters including sample size, relative risk, time-varying baseline risks, and risk interval length. The random-adjustment approach has very good performance in almost all considered settings. The fixed-adjustment approach can be used as a good alternative when the number of events used to estimate the time-varying baseline risks is at least the number of events used to estimate the relative risk, which is almost always the case. We successfully identified settings in which the fixed-adjustment approach can be used as a good alternative and provided guidelines on the selection and implementation of appropriate analyses for the self-controlled risk interval design. Copyright © 2015 John Wiley & Sons, Ltd.

Evaluation of Resources Necessary for Provision of Trauma Care in Botswana: An Initiative for a Local System.

PubMed

Mwandri, Michael B; Hardcastle, Timothy C

2018-06-01

Developing countries face the highest incidence of trauma, and on the other hand, they do not have resources for mitigating the scourge of these injuries. The World Health Organization through the Essential Trauma Care (ETC) project provides recommendations for improving management of the injured and building up of systems that are effective in low-middle-income countries (LMICs). This study uses ETC project recommendations and other trauma-care guidelines to evaluate the current status of the resources and organizational structures necessary for optimal trauma care in Botswana; an African country with relatively good health facilities network, subsidized public hospital care and a functioning Motor Vehicle Accident fund covering road traffic collision victims. A cross-sectional descriptive design employed convenience sampling for recruiting high-volume trauma hospitals and selecting candidates. A questionnaire, checklist, and physical verification of resources were utilized to evaluate resources, staff knowledge, and organization-of-care and hospital capabilities. Results are provided in plain descriptive language to demonstrate the findings. Necessary consumables, good infrastructure, adequate numbers of personnel and rehabilitation services were identified all meeting or exceeding ETC recommendations. Deficiencies were noted in staff knowledge of initial trauma care, district hospital capability to provide essential surgery, and the organization of trauma care. The good level of resources available in Botswana may be used to improve trauma care: To further this process, more empowering of high-volume trauma hospitals by adopting trauma-care recommendations and inclusive trauma-system approaches are desirable. The use of successful examples on enhanced surgical skills and capabilities, effective trauma-care resource management, and leadership should be encouraged.

Heterogeneous electrochemical CO2 reduction using nonmetallic carbon-based catalysts: current status and future challenges

NASA Astrophysics Data System (ADS)

Ma, Tao; Fan, Qun; Tao, Hengcong; Han, Zishan; Jia, Mingwen; Gao, Yunnan; Ma, Wangjing; Sun, Zhenyu

2017-11-01

Electrochemical CO2 reduction (ECR) offers an important pathway for renewable energy storage and fuels production. It still remains a challenge in designing highly selective, energy-efficient, robust, and cost-effective electrocatalysts to facilitate this kinetically slow process. Metal-free carbon-based materials have features of low cost, good electrical conductivity, renewability, diverse structure, and tunability in surface chemistry. In particular, surface functionalization of carbon materials, for example by doping with heteroatoms, enables access to unique active site architectures for CO2 adsorption and activation, leading to interesting catalytic performances in ECR. We aim to provide a comprehensive review of this category of metal-free catalysts for ECR, providing discussions and/or comparisons among different nonmetallic catalysts, and also possible origin of catalytic activity. Fundamentals and some future challenges are also described.

Objective for monitoring the corona discharge

NASA Astrophysics Data System (ADS)

Obrezkov, Andrey; Rodionov, Andrey Yu.; Pisarev, Viktor N.; Chivanov, Alexsey N.; Baranov, Yuri P.; Korotaev, Valery V.

2016-04-01

Remote optoelectronic probing is one of the most actual aspects of overhead electric line maintenances. By installing such systems on a helicopter (for example) it becomes possible to monitor overhead transmission line status and to search damaged parts of the lines. Thermal and UV-cameras are used for more effective diagnostic. UV-systems are fitted with filters, that attenuate visible spectrum, which is an undesired type of signal. Also these systems have a wide view angle for better view and proper diagnostics. For even more effectiveness, it is better to use several spectral channels: like UV and IR. Such spectral selection provides good noise reduction. Experimental results of spectral parameters of the wide view angle multispectral objective for such systems are provided in this report. There is also data on point spread function, UV and IR scattering index data and technical requirements for detectors.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Strons, Philip; Bailey, James L.

Anemometer readings alone cannot provide a complete picture of air flow patterns at an open gloveport. Having a means to visualize air flow for field tests in general provides greater insight by indicating direction in addition to the magnitude of the air flow velocities in the region of interest. Furthermore, flow visualization is essential for Computational Fluid Dynamics (CFD) verification, where important modeling assumptions play a significant role in analyzing the chaotic nature of low-velocity air flow. A good example is shown Figure 1, where an unexpected vortex pattern occurred during a field test that could not have been measuredmore » relying only on anemometer readings. Here by, observing and measuring the patterns of the smoke flowing into the gloveport allowed the CFD model to be appropriately updated to match the actual flow velocities in both magnitude and direction.« less

Functional assay of Salmonella typhi OmpC using reconstituted large unilamellar vesicles: a general method for characterization of outer membrane proteins.

PubMed

Sundara Baalaji, N; Mathew, M K; Krishnaswamy, S

2006-10-01

The immunodominant trimeric beta-barrel outer membrane protein OmpC from Salmonella typhi, the causative agent of typhoid, has been functionally characterized here. The activity in the vesicle environment was studied in vitro using OmpC reconstituted into proteoliposomes. Passage of polysaccharides and polyethyleneglycols through OmpC has been examined to determine the permeability properties. The relative rate of neutral solute flux yields a radius of 1.1 nm for the S. typhi OmpC pore. This is almost double the pore size of Escherichia coli. This provides an example of large pore size present in the porins that form trimers as in the general bacterial porin family. The method used in this study provides a good membrane model for functional studies of porins.

[Leadership strategies--the Bible as a guide to management in the health care system].

PubMed

Kudlacek, Stefan; Meran, Johannes G

2006-06-01

Management and leadership are an integral part of any organisation, to optimise procedures and increase efficiency. Aims, ideals and structures first need to be defined for tasks to be carried out successfully, particularly in difficult times. A good example for the way communities can effectively and with conviction pass on their values and standpoints from generation to generation, grow in strength and also influence their surroundings is provided by religion. This paper focuses leadership provided by charismatic personalities within the Jewish and Christian religions. Monasteries have run hospitals without governmental support ever since the Middle Ages. Leadership within today's health care system calls for a variety of strategies in the different phases of development. In times of limited resources and multifarious societies, leadership implies both a scientific as well as an ethical challenge.

East Europe Report.

DTIC Science & Technology

1986-09-10

Regulations (Katalin Szoghy; HUNGARIAN DIGEST , No 4, 1986) 54 . i KOMMUNIST Praises Kadar’s ’Solid Marxist Policies’ (Petr N. Fedosejev; NEPSZABADSAG, 2...good varieties of sheep, hogs and broiler chickens have been obtained with very good useful traits. Many more examples of this kind may be given...POLITICS HUNGARY PROGRAM ANNOUNCED TO COORDINATE LEGISLATION, REGULATIONS Budapest HUNGARIAN DIGEST in English No 4, 1986 pp 55-57 [Article by Katalin

On Informatics Diagnostics and Informatics Therapeutics - Good Medical Informatics Research Is Needed Here.

PubMed

Haux, Reinhold

2017-01-01

In the era of digitization some new procedures play an increasing role for diagnosis as well as for therapy: informatics diagnostics and informatics therapeutics. Challenges for such procedures are described. It is discussed, when research on such diagnostics and therapeutics can be regarded as good research. Examples are mentioned for informatics diagnostics and informatics therapeutics, which are based on health-enabling technologies.

Comparative Study on Cushion Performance Between 3D Printed Kelvin Structure and 3D Printed Lattice Structure

NASA Astrophysics Data System (ADS)

Priyadarshini, Lakshmi

Frequently transported packaging goods are more prone to damage due to impact, jolting or vibration in transit. Fragile goods, for example, glass, ceramics, porcelain are susceptible to mechanical stresses. Hence ancillary materials like cushions play an important role when utilized within package. In this work, an analytical model of a 3D cellular structure is established based on Kelvin model and lattice structure. The research will provide a comparative study between the 3D printed Kelvin unit structure and 3D printed lattice structure. The comparative investigation is based on parameters defining cushion performance such as cushion creep, indentation, and cushion curve analysis. The applications of 3D printing is in rapid prototyping where the study will provide information of which model delivers better form of energy absorption. 3D printed foam will be shown as a cost-effective approach as prototype. The research also investigates about the selection of material for 3D printing process. As cushion development demands flexible material, three-dimensional printing with material having elastomeric properties is required. Further, the concept of cushion design is based on Kelvin model structure and lattice structure. The analytical solution provides the cushion curve analysis with respect to the results observed when load is applied over the cushion. The results are reported on basis of attenuation and amplification curves.

TU-F-BRD-01: Biomedical Informatics for Medical Physicists

DOE Office of Scientific and Technical Information (OSTI.GOV)

Phillips, M; Kalet, I; McNutt, T

Biomedical informatics encompasses a very large domain of knowledge and applications. This broad and loosely defined field can make it difficult to navigate. Physicists often are called upon to provide informatics services and/or to take part in projects involving principles of the field. The purpose of the presentations in this symposium is to help medical physicists gain some knowledge about the breadth of the field and how, in the current clinical and research environment, they can participate and contribute. Three talks have been designed to give an overview from the perspective of physicists and to provide a more in-depth discussionmore » in two areas. One of the primary purposes, and the main subject of the first talk, is to help physicists achieve a perspective about the range of the topics and concepts that fall under the heading of 'informatics'. The approach is to de-mystify topics and jargon and to help physicists find resources in the field should they need them. The other talks explore two areas of biomedical informatics in more depth. The goal is to highlight two domains of intense current interest--databases and models--in enough depth into current approaches so that an adequate background for independent inquiry is achieved. These two areas will serve as good examples of how physicists, using informatics principles, can contribute to oncology practice and research. Learning Objectives: To understand how the principles of biomedical informatics are used by medical physicists. To put the relevant informatics concepts in perspective with regard to biomedicine in general. To use clinical database design as an example of biomedical informatics. To provide a solid background into the problems and issues of the design and use of data and databases in radiation oncology. To use modeling in the service of decision support systems as an example of modeling methods and data use. To provide a background into how uncertainty in our data and knowledge can be incorporated into modeling methods.« less

What's Wrong with Economics Textbooks?

ERIC Educational Resources Information Center

Culyer, A. J.

1985-01-01

Many things are wrong with college level economics textbooks. For example, they are too ahistorical, too particularist, or unsystematically eclectic. The requirements of a good college economics textbook are examined. (RM)

Separation and simultaneous quantitation of PGF2α and its epimer 8-iso-PGF2α using modifier-assisted differential mobility spectrometry tandem mass spectrometry.

PubMed

Liang, Chunsu; Sun, Hui; Meng, Xiangjun; Yin, Lei; Fawcett, J Paul; Yu, Huaidong; Liu, Ting; Gu, Jingkai

2018-03-01

Because many therapeutic agents are contaminated by epimeric impurities or form epimers as a result of metabolism, analytical tools capable of determining epimers are increasingly in demand. This article is a proof-of-principle report of a novel DMS-MS/MS method to separate and simultaneously quantify epimers, taking PGF2 α and its 8-epimer, 8- iso -PGF2 α , as an example. Good accuracy and precision were achieved in the range of 10-500 ng/mL with a run time of only 1.5 min. Isopropanol as organic modifier facilitated a good combination of sensitivity and separation. The method is the first example of the quantitation of epimers without chromatographic separation.

Valuation of rangeland ecosystem services

USGS Publications Warehouse

Gascoigne, W.R.

2011-01-01

Economic valuation lends itself well to the anthropocentric orientation of ecosystem services. An economic perspective on ecosystems portrays them as natural assets providing a flow of goods and services valuable to individuals and society collectively. A few examples include the purification of drinking water, reduced risk from flooding and other extreme events, pollination of agricultural crops, climate regulation, and recreation opportunities from plant and animal habitat maintenance, among many others. Once these goods and services are identified and quantified, they can be monetized to complete the valuation process. The monetization of ecosystem goods and services (in the form of dollars) provides a common metric that allows for cross-comparison of attributes and evaluation of differing ecological scenarios. Complicating the monetization process is the fact that most of these goods and services are public and non-market in nature; meaning they are non-rival and non-exclusive and are typically not sold in a traditional market setting where monetary values are revealed. Instead, one must employ non-market valuation techniques, with primary valuation methods typically being very time and resource consuming, intimidating to non-economists, and often impractical. For these reasons, benefit transfer methods have gained popularity. This methodology harnesses the primary collection results of existing studies to make inferences about the economic values of non-market goods and services at an alternative policy site (in place and/or in time). For instance, if a primary valuation study on oak reestablishment on rangelands in southern California yielded a value of $30 per-acre associated with water regulation, this result can be transferred, with some adjustments, to say something about the value of an acre of oaks on rangelands in northern portions of the state. The economic valuation of rangeland ecosystem services has many roles. Economic values may be used as input into analyzing the costs and benefits associated with policies being proposed, or possibly already implemented. For example, with monetized values acting as a common metric, one could compare the 'benefits' of converting a rangeland ecosystem for commercial development (perhaps estimated at the market value of the developed land) with the foregone ecosystem service values (in addition to any land income lost) resulting from that land conversion. Similarly, ecosystem service values can be used to determine the level of return on an investment. rhis is a primary objective for private land conservation organizations who typically have very limited resources. Ecosystem service valuation can also have a role in damage assessments from incidents that require compensation such as oil spills. Additionally, valuation can be very informative when investigating regulatory programs that trade ecological assets such as wetland mitigation programs. Typically these programs are based simply on an 'acre for acre' criterion, and do not take into consideration varying welfare values associated with that ecosystem. Lastly, and most fundamental, ecosystem service valuation serves as a recognition tool for people of all backgrounds. Identifying and valuing ecosystem goods and services on rangelands brings to light the value these natural assets have to human welfare that often remain hidden do to their public and non-market attributes. This type of recognition is vital to the preservation of rangeland ecosystems in the future and the many ecological benefits they provide.

Cavity approach to noisy learning in nonlinear perceptrons.

PubMed

Luo, P; Michael Wong, K Y

2001-12-01

We analyze the learning of noisy teacher-generated examples by nonlinear and differentiable student perceptrons using the cavity method. The generic activation of an example is a function of the cavity activation of the example, which is its activation in the perceptron that learns without the example. Mean-field equations for the macroscopic parameters and the stability condition yield results consistent with the replica method. When a single value of the cavity activation maps to multiple values of the generic activation, there is a competition in learning strategy between preferentially learning an example and sacrificing it in favor of the background adjustment. We find parameter regimes in which examples are learned preferentially or sacrificially, leading to a gap in the activation distribution. Full phase diagrams of this complex system are presented, and the theory predicts the existence of a phase transition from poor to good generalization states in the system. Simulation results confirm the theoretical predictions.

A User Modelling Approach for Computer-Based Critiquing

DTIC Science & Technology

1990-01-01

example a CAD/CAM system). Com- puters are good for simulating in circumstances where training on the actual equip- 13 ment (for example a power plant or...system. It is an environment in which simulated devices, such as steam plant controllers, can be assembled and operated. Students can assemble a...Con- cordia hypermedia system, graphics can be integrated easily. Concordia is a hy- permedia development and presentation system available on the

Wide Band Spurious Suppression of Multi-Strip Resonator BPF —Comprehensive Way to Suppress Spurious Responses in BPFs—

NASA Astrophysics Data System (ADS)

Awai, Ikuo

A new comprehensive method to suppress the spurious modes in a BPF is proposed taking the multi-strip resonator BPF as an example. It consists of disturbing the resonant frequency, coupling coefficient and external Q of the higher-order modes at the same time. The designed example has shown an extraordinarily good out-of-band response in the computer simulation.

15 CFR Supplement No. 1 to Part 746 - Examples of Luxury Goods

Code of Federal Regulations, 2010 CFR

2010-01-01

... (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE EXPORT ADMINISTRATION REGULATIONS...) Personal digital assistants (PDAs) (3) Personal digital music players (4) Computer laptops (g...

The importance of good seed

Treesearch

Robert P. Karrfalt

2013-01-01

The importance of seed to human culture and conservation of the natural world is briefly discussed. The effect of seed on seedling quality and cost is described through several examples and illustrations.

Health education in school children.

PubMed

Tragler, A

1991-05-01

A researcher compared responses to a pretest questionnaire with those a posttest questionnaire completed by 304 12-16 year old school children in India to assess health knowledge of school children. The children attended either a public school or a private school in Bombay or a rural school in Kazli operated by a charitable institution. The researcher administered the posttest 4 weeks after health education talks and demonstrations. Before the health education course, children at all 3 schools had limited health knowledge. For example, 19-52% of the children exhibited poor knowledge and only 2% exhibited good knowledge (all from the public school). After undergoing health education, 52% of the children in the public school had good knowledge and 37% had very good knowledge. These parallel figures for the private and rural schools were 67% and 23% and 76% respectively. Nutrition knowledge was considerably better than knowledge of immunization and hygiene before the health education course. 6% of the students at the private school had good knowledge of nutrition compared to only 2% for immunization and 1% for hygiene. Nutrition knowledge did increase after health education, but not as markedly as did immunization knowledge. For example, good and very good immunization knowledge was 60% for the public school, 76% for the private school, and 97% for the rural school compared to 0-3% prior to health education. Moreover health education cast away most of the misconceptions about the cause of worm infections and tetanus, the ability to beet roots to improve blood quality, and the ability of milk to sustain a health life during the 1st year.

History, a projection of the future: A rotary wing perspective

NASA Technical Reports Server (NTRS)

Huston, Robert J.

1996-01-01

The success and failure of past vehicle concepts is reviewed in an attempt to highlight some of the advanced vehicle concepts attempted in the past failed because of a lack of appreciation, by both the sponsors and the developer, for the technical and societal requirements critical to their success. This paper will review the history of some attempts to provide both good hover and forward flight efficiency and will point out some of the technical and societal obstacles encountered. Two examples, that of the tiltrotor and tiltwing vehicles. will be highlighted show the different paths followed by a successful and an unsuccessful concept. The outlook for future VTOL/rotary wing concepts will be evaluated.

Structural DNA nanotechnology: from design to applications.

PubMed

Zadegan, Reza M; Norton, Michael L

2012-01-01

The exploitation of DNA for the production of nanoscale architectures presents a young yet paradigm breaking approach, which addresses many of the barriers to the self-assembly of small molecules into highly-ordered nanostructures via construct addressability. There are two major methods to construct DNA nanostructures, and in the current review we will discuss the principles and some examples of applications of both the tile-based and DNA origami methods. The tile-based approach is an older method that provides a good tool to construct small and simple structures, usually with multiply repeated domains. In contrast, the origami method, at this time, would appear to be more appropriate for the construction of bigger, more sophisticated and exactly defined structures.

Fruit ripening using hyperspectral imaging

NASA Astrophysics Data System (ADS)

., Swetha; Chidangil, Santhosh; Karpate, Tanvi; Asundi, Anand

2017-06-01

The ripening of fruits is associated with changes, in some cases subtle, in the color of the fruit. Traditionally spectroscopy used to measure these subtle changes and infer the ripeness of fruits. Spectrometers provides high-resolution but only measure a small area of the fruit. That might not be a good indicator of the overall ripeness. In this paper, we propose a compact tunable LED based hyper spectral imaging system that scans through a set of wavelengths and images, the reflectance from the whole fruit. Based on the type of fruit, only specific wavelengths need to be scanned. Following a validation using a Rubik's cube, an example banana going through its ripening cycles is used to demonstrate the system.

Refugee Students at College and University: Improving Access and Support

NASA Astrophysics Data System (ADS)

Hannah, Janet

1999-03-01

This article summarizes the findings and recommendations of a study into access to, and experience of, colleges of further education and universities by refugees in Sydney, Australia. The study sought to identify examples of institutional good practice which are potentially transferable to other major host countries for refugees in the developed world. It focuses upon the factors influencing the decision to enter college or university, sources and usefulness of information and advice, access courses and special entry schemes, the recognition of prior learning and overseas qualifications and institutional sensitivity and support. It concludes with a series of recommendations for providers of further and higher education to improve access and support for students from refugee backgrounds.

Impact of Machine Virtualization on Timing Precision for Performance-critical Tasks

NASA Astrophysics Data System (ADS)

Karpov, Kirill; Fedotova, Irina; Siemens, Eduard

2017-07-01

In this paper we present a measurement study to characterize the impact of hardware virtualization on basic software timing, as well as on precise sleep operations of an operating system. We investigated how timer hardware is shared among heavily CPU-, I/O- and Network-bound tasks on a virtual machine as well as on the host machine. VMware ESXi and QEMU/KVM have been chosen as commonly used examples of hypervisor- and host-based models. Based on statistical parameters of retrieved distributions, our results provide a very good estimation of timing behavior. It is essential for real-time and performance-critical applications such as image processing or real-time control.

Case four. Synergistic strategy development.

PubMed

Taylor, J D

1990-01-01

Mercy Medical Center is a 467 bed, not-for-profit teaching hospital affiliated with a multispecialty group practice and health maintenance organization through contractual arrangements. Historically, strategy development was not helping the hospital remain viable while accomplishing its mission. Strategic planning was fragmented, not focused toward concern for balance of the overall product line, total growth of the organization or the best use of resources. The hospital did not involve the affiliated group practice or HMO in its planning. This last case in Chapter One describes the pursuit of synergy through strategy formulation. The case provides a good example of what Kanter describes as a post-entrepreneurial organization, striving for advantage through collaboration and linkage with "PALs."

Quantitative aspects of inductively coupled plasma mass spectrometry

NASA Astrophysics Data System (ADS)

Bulska, Ewa; Wagner, Barbara

2016-10-01

Accurate determination of elements in various kinds of samples is essential for many areas, including environmental science, medicine, as well as industry. Inductively coupled plasma mass spectrometry (ICP-MS) is a powerful tool enabling multi-elemental analysis of numerous matrices with high sensitivity and good precision. Various calibration approaches can be used to perform accurate quantitative measurements by ICP-MS. They include the use of pure standards, matrix-matched standards, or relevant certified reference materials, assuring traceability of the reported results. This review critically evaluates the advantages and limitations of different calibration approaches, which are used in quantitative analyses by ICP-MS. Examples of such analyses are provided. This article is part of the themed issue 'Quantitative mass spectrometry'.

Acid-promoted Bicyclization of Diaryl Alkynes: Synthesis of 2H-Indazoles with in situ Generated Diazonium Salt as Nitrogen Source.

PubMed

Zhang, Cheng; Chang, Sailan; Dong, Shanliang; Qiu, Lihua; Xu, Xinfang

2018-06-08

An unprecedented transition-metal-free tandem bicyclization of diaryl alkynes has been disclosed, which provides a streamlined access to a range of polycyclic 2H-indazoles in high to excellent yields. The salient features of this reaction include readily available starting materials, good functional group compatibility, mild reaction conditions, no column chromatography, high bond-formation efficiency, and ease in further transformations. Notably, this is the first example for the synthesis of 2H-indazoles with in situ generated diazonium salt as the nitrogen source, and a mechanistic rationale involving an acid-promoted tandem diazonium salt formation/bicyclization process is discussed.

Uncovering a reconstructive solid-solid phase transition in a metal-organic framework.

PubMed

Longley, L; Li, N; Wei, F; Bennett, T D

2017-11-01

A nanoporous three-dimensional metal-organic framework (MOF), ZnPurBr undergoes a transition to a previously unreported high-temperature phase, ZnPurBr-ht. The transition, which proceeds without mass loss, is uncovered through the use of differential scanning calorimetry (DSC). The new crystal structure was solved using single-crystal X-ray diffraction, and the mechanical properties of both phases investigated by nanoindentation and density functional theory. The anisotropy of the calculated Young's moduli showed good agreement with the crystallographic alignment of the stiff purinate organic linker. The results provide a prototypical example of the importance of the use of DSC in the MOF field, where its use is not currently standard in characterization.

Mean-field approximation for spacing distribution functions in classical systems

NASA Astrophysics Data System (ADS)

González, Diego Luis; Pimpinelli, Alberto; Einstein, T. L.

2012-01-01

We propose a mean-field method to calculate approximately the spacing distribution functions p(n)(s) in one-dimensional classical many-particle systems. We compare our method with two other commonly used methods, the independent interval approximation and the extended Wigner surmise. In our mean-field approach, p(n)(s) is calculated from a set of Langevin equations, which are decoupled by using a mean-field approximation. We find that in spite of its simplicity, the mean-field approximation provides good results in several systems. We offer many examples illustrating that the three previously mentioned methods give a reasonable description of the statistical behavior of the system. The physical interpretation of each method is also discussed.

An extensive review of commercial product labels the good, bad and ugly.

PubMed

Mrvos, R; Dean, B S; Krenzelok, E P

1986-02-01

Cautions and warnings on consumer products play an important role in the prevention and treatment of poison exposures. Frequently those exposed will follow the directions before calling the poison center, physician or emergency room. An extensive label review of 200 commercial products was conducted to determine if medical treatment advice was correct, if the general public was able to comprehend warning statements, and if warnings were adequate. We conclude there are products available that provide precise, correct information. However, there are many that contain incorrect, misleading, and often dangerous information to an unsuspecting public. Various examples of both types are given to make the poison information specialist aware of what information is presented.

We really need to talk: adapting FDA processes to rapid change.

PubMed

Lykken, Sara

2013-01-01

The rapidly evolving realm of modern commerce strains traditional regulatory paradigms. This paper traces the historical evolution of FDA crisis-response regulation and provides examples of ways in which the definitions and procedures resulting from that past continue to be challenged by new products as market entrants, some in good faith and others not, take actions that create disconnects between actual product and marketing controls and those that consumers might expect. The paper then explores some of the techniques used by other federal agencies that have faced similar challenges in environments characterized by rapid innovation, and draws from this analysis suggestions for improvement of the FDA's warning letter system.

Role of Process Control in Improving Space Vehicle Safety A Space Shuttle External Tank Example

NASA Technical Reports Server (NTRS)

Safie, Fayssal M.; Nguyen, Son C.; Burleson, Keith W.

2006-01-01

Developing a safe and reliable space vehicle requires good design and good manufacturing, or in other words "design it right and build it right". A great design can be hard to build or manufacture mainly due to difficulties related to quality. Specifically, process control can be a challenge. As a result, the system suffers from low quality which leads to low reliability and high system risk. The Space Shuttle has experienced some of those cases, but has overcome these difficulties through extensive redesign efforts and process enhancements. One example is the design of the hot gas temperature sensor on the Space Shuttle Main Engine (SSME), which resulted in failure of the sensor in flight and led to a redesign of the sensor. The most recent example is the Space Shuttle External Tank (ET) Thermal Protection System (TPS) reliability issues that contributed to the Columbia accident. As a result, extensive redesign and process enhancement activities have been performed over the last two years to minimize the sensitivities and difficulties of the manual TPS application process.

The missing link: Creating science policies that facilitate the use of research in environmental and water-related decision-making

NASA Astrophysics Data System (ADS)

Dilling, L.; Pielke, R.; Sarewitz, D.

2005-12-01

Despite all good intentions, it is clear that science intended to serve decision making needs often fails to achieve that purpose. The aftermath of Hurricane Katrina provides a recent, tragic example. The reasons for failures of science to support decision making are varied. Researchers studying forecasts of climate variability have found, for example, cases where information provided is not needed; information is needed but not provided; information lacks regional specificity; information is provided in an inaccessible form; poor communication exists between potential users and providers; there is a lack of trust in information or deliverers; institutional constraints prevent use of new information; and so on. Traditional science policies have institutionalized the separation of the conduct of science from its application and use. It is clear that as long as such a separation, reinforced by tradition, institution and culture, is the dominant paradigm of science policies, the efficient and effective use of science in environmental and water-related decision making will be hampered. We introduce here a research methodology for examining the decision making involved in setting science policies for research aimed at being useful. Based on the economic concept, the notion of "reconciling supply and demand" for information offers a framework for identifying missed opportunities where science policies can be adjusted to improve the usefulness of a given research portfolio. We present results from a case study focused on internal science policies and decision making within the Regional Integrated Sciences and Assessments (RISA) projects. The RISA program aims to "expand the range of choices available to private and public communities in a region, by...enabling practical decisions...using research-based knowledge" and so provides an excellent opportunity for harvesting lessons for creating usable science.

Speaking Up: Veterinary Ethical Responsibilities and Animal Welfare Issues in Everyday Practice

PubMed Central

Hernandez, Elein; Fawcett, Anne; Brouwer, Emily; Rau, Jeff

2018-01-01

Simple Summary Veterinarians have an ethical obligation to provide good care for the animals that they see in practice. However, at times, there may be conflicts between the interests of animal caregivers or owners, the interests of veterinarians and the interests of animals. We provide an overview of why and how veterinary ethics is taught to veterinary students, as well as providing a context for thinking about veterinary ethical challenges and animal welfare issues. We argue that veterinarians are ethically obliged to speak up and ask questions when problems arise or are seen and provide a series of clinical case examples in which there is scope for veterinarians to improve animal welfare by ‘speaking up’. Abstract Although expectations for appropriate animal care are present in most developed countries, significant animal welfare challenges continue to be seen on a regular basis in all areas of veterinary practice. Veterinary ethics is a relatively new area of educational focus but is thought to be critically important in helping veterinarians formulate their approach to clinical case management and in determining the overall acceptability of practices towards animals. An overview is provided of how veterinary ethics are taught and how common ethical frameworks and approaches are employed—along with legislation, guidelines and codes of professional conduct—to address animal welfare issues. Insufficiently mature ethical reasoning or a lack of veterinary ethical sensitivity can lead to an inability or difficulty in speaking up about concerns with clients and ultimately, failure in their duty of care to animals, leading to poor animal welfare outcomes. A number of examples are provided to illustrate this point. Ensuring that robust ethical frameworks are employed will ultimately help veterinarians to “speak up” to address animal welfare concerns and prevent future harms. PMID:29361786

Differential-associative processing or example elaboration: Which strategy is best for learning the definitions of related and unrelated concepts?

PubMed

Hannon, Brenda

2012-10-01

Definitions of related concepts (e.g., genotype - phenotype ) are prevalent in introductory classes. Consequently, it is important that educators and students know which strategy(s) work best for learning them. This study showed that a new comparative elaboration strategy, called differential-associative processing, was better for learning definitions of related concepts than was an integrative elaborative strategy, called example elaboration. This outcome occurred even though example elaboration was administered in a naturalistic way (Experiment 1) and students spent more time in the example elaboration condition learning (Experiments 1, 2, 3), and generating pieces of information about the concepts (Experiments 2 and 3). Further, with unrelated concepts ( morpheme-fluid intelligence ), performance was similar regardless if students used differential-associative processing or example elaboration (Experiment 3). Taken as a whole, these results suggest that differential-associative processing is better than example elaboration for learning definitions of related concepts and is as good as example elaboration for learning definitions of unrelated concepts.

Differential-associative processing or example elaboration: Which strategy is best for learning the definitions of related and unrelated concepts?

PubMed Central

Hannon, Brenda

2013-01-01

Definitions of related concepts (e.g., genotype–phenotype) are prevalent in introductory classes. Consequently, it is important that educators and students know which strategy(s) work best for learning them. This study showed that a new comparative elaboration strategy, called differential-associative processing, was better for learning definitions of related concepts than was an integrative elaborative strategy, called example elaboration. This outcome occurred even though example elaboration was administered in a naturalistic way (Experiment 1) and students spent more time in the example elaboration condition learning (Experiments 1, 2, 3), and generating pieces of information about the concepts (Experiments 2 and 3). Further, with unrelated concepts (morpheme-fluid intelligence), performance was similar regardless if students used differential-associative processing or example elaboration (Experiment 3). Taken as a whole, these results suggest that differential-associative processing is better than example elaboration for learning definitions of related concepts and is as good as example elaboration for learning definitions of unrelated concepts. PMID:24347814

Standing Naval Forces and Global Security

DTIC Science & Technology

1993-06-04

standards an- good engineering practices. The team submits a r:-,cr: to !PPC recommending that the prcject be accepted b NATO. 8. Audit . The...established. A system of common funds and trailing audits must be in effect to pay for the infrastructure. NATO infrastructure appears to be a good example to...Search And Rescue and maritime safety monitor marine polution 6. sharing maritime inteiiigence1 5 Commodore Bateman foresees coupling these activities or

Reasons for Letter Contracts.

DTIC Science & Technology

1980-09-01

accelerated Initial Operational Capability (IOC). The TOW-DRAGON PM reacted accordingly. This also is a good example of a letter contract award to permit...Government. Good pricing depends pri- marily upon the exercise of sound judgement by all personnel concerned with the procurement. I: 3-801.2...Contracts. (a) The written determination required by DAR 3-408(c)(1) shall in- clude an outline of the reaons for a letter contract and the alternatives

Infusing Social Responsibility into the Curriculum and Cocurriculum: Campus Examples

ERIC Educational Resources Information Center

Reason, Robert D.

2013-01-01

This chapter highlights good practices and lessons learned for infusing social responsibility--contributing to the larger community and taking seriously the perspectives of others--as outcomes of college.

Karst Landscape, China

NASA Image and Video Library

2014-04-28

Karst topography is a geological formation shaped by the dissolution of layers of soluble rock such as limestone. A good example is found in Guangxi Province in southeast China, as seen by NASA Terra spacecraft.

Adventures in data citation: sorghum genome data exemplifies the new gold standard

PubMed Central

2012-01-01

Scientific progress is driven by the availability of information, which makes it essential that data be broadly, easily and rapidly accessible to researchers in every field. In addition to being good scientific practice, provision of supporting data in a convenient way increases experimental transparency and improves research efficiency by reducing unnecessary duplication of experiments. There are, however, serious constraints that limit extensive data dissemination. One such constraint is that, despite providing a major foundation of data to the advantage of entire community, data producers rarely receive the credit they deserve for the substantial amount of time and effort they spend creating these resources. In this regard, a formal system that provides recognition for data producers would serve to incentivize them to share more of their data. The process of data citation, in which the data themselves are cited and referenced in journal articles as persistently identifiable bibliographic entities, is a potential way to properly acknowledge data output. The recent publication of several sorghum genomes in Genome Biology is a notable first example of good data citation practice in the field of genomics and demonstrates the practicalities and formatting required for doing so. It also illustrates how effective use of persistent identifiers can augment the submission of data to the current standard scientific repositories. PMID:22571506

Improved triage and emergency care for children reduces inpatient mortality in a resource-constrained setting.

PubMed

Molyneux, Elizabeth; Ahmad, Shafique; Robertson, Ann

2006-04-01

Early assessment, prioritization for treatment and management of sick children attending a health service are critical to achieving good outcomes. Many hospitals in developing countries see large numbers of patients and have few staff, so patients often have to wait before being assessed and treated. We present the example of a busy Under-Fives Clinic that provided outpatient services, immunizations and treatment for medical emergencies. The clinic was providing an inadequate service resulting in some inappropriate admissions and a high case-fatality rate. We assessed the deficiencies and sought resources to improve services. A busy paediatric outpatient clinic in a public tertiary care hospital in Blantyre, Malawi. The main changes we made were to train staff in emergency care and triage, improve patient flow through the department and to develop close cooperation between inpatient and outpatient services. Training coincided with a restructuring of the physical layout of the department. The changes were put in place when the department reopened in January 2001. Improvements in the process and delivery of care and the ability to prioritize clinical management are essential to good practice. Making the changes described above has streamlined the delivery of care and led to a reduction in inpatient mortality from 10-18% before the changes were made (before 2001) to 6-8% after.

TH-E-19A-01: Quality and Safety in Radiation Therapy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ford, E; Ezzell, G; Miller, B

2014-06-15

Clinical radiotherapy data clearly demonstrate the link between the quality and safety of radiation treatments and the outcome for patients. The medical physicist plays an essential role in this process. To ensure the highest quality treatments, the medical physicist must understand and employ modern quality improvement techniques. This extends well beyond the duties traditionally associated with prescriptive QA measures. This session will review the current best practices for improving quality and safety in radiation therapy. General elements of quality management will be reviewed including: what makes a good quality management structure, the use of prospective risk analysis such as FMEA,more » and the use of incident learning. All of these practices are recommended in society-level documents and are incorporated into the new Practice Accreditation program developed by ASTRO. To be effective, however, these techniques must be practical in a resource-limited environment. This session will therefore focus on practical tools such as the newly-released radiation oncology incident learning system, RO-ILS, supported by AAPM and ASTRO. With these general constructs in mind, a case study will be presented of quality management in an SBRT service. An example FMEA risk assessment will be presented along with incident learning examples including root cause analysis. As the physicist's role as “quality officer” continues to evolve it will be essential to understand and employ the most effective techniques for quality improvement. This session will provide a concrete overview of the fundamentals in quality and safety. Learning Objectives: Recognize the essential elements of a good quality management system in radiotherapy. Understand the value of incident learning and the AAPM/ASTRO ROILS incident learning system. Appreciate failure mode and effects analysis as a risk assessment tool and its use in resource-limited environments. Understand the fundamental principles of good error proofing that extends beyond traditional prescriptive QA measures.« less

Exact goodness-of-fit tests for Markov chains.

PubMed

Besag, J; Mondal, D

2013-06-01

Goodness-of-fit tests are useful in assessing whether a statistical model is consistent with available data. However, the usual χ² asymptotics often fail, either because of the paucity of the data or because a nonstandard test statistic is of interest. In this article, we describe exact goodness-of-fit tests for first- and higher order Markov chains, with particular attention given to time-reversible ones. The tests are obtained by conditioning on the sufficient statistics for the transition probabilities and are implemented by simple Monte Carlo sampling or by Markov chain Monte Carlo. They apply both to single and to multiple sequences and allow a free choice of test statistic. Three examples are given. The first concerns multiple sequences of dry and wet January days for the years 1948-1983 at Snoqualmie Falls, Washington State, and suggests that standard analysis may be misleading. The second one is for a four-state DNA sequence and lends support to the original conclusion that a second-order Markov chain provides an adequate fit to the data. The last one is six-state atomistic data arising in molecular conformational dynamics simulation of solvated alanine dipeptide and points to strong evidence against a first-order reversible Markov chain at 6 picosecond time steps. © 2013, The International Biometric Society.

15 CFR Supplement No. 1 to Part 746 - Examples of Luxury Goods

Code of Federal Regulations, 2013 CFR

2013-01-01

... (other than public transport), including station wagons (3) Racing cars, snowmobiles, and motorcycles (4...) Musical instruments (2) Recreational sports equipment (i) Alcoholic beverages: wine, beer, ales, and...

15 CFR Supplement No. 1 to Part 746 - Examples of Luxury Goods

Code of Federal Regulations, 2012 CFR

2012-01-01

... (other than public transport), including station wagons (3) Racing cars, snowmobiles, and motorcycles (4...) Musical instruments (2) Recreational sports equipment (i) Alcoholic beverages: wine, beer, ales, and...

15 CFR Supplement No. 1 to Part 746 - Examples of Luxury Goods

Code of Federal Regulations, 2011 CFR

2011-01-01

... (other than public transport), including station wagons (3) Racing cars, snowmobiles, and motorcycles (4...) Musical instruments (2) Recreational sports equipment (i) Alcoholic beverages: wine, beer, ales, and...

15 CFR Supplement No. 1 to Part 746 - Examples of Luxury Goods

Code of Federal Regulations, 2014 CFR

2014-01-01

... (other than public transport), including station wagons (3) Racing cars, snowmobiles, and motorcycles (4...) Musical instruments (2) Recreational sports equipment (i) Alcoholic beverages: wine, beer, ales, and...

Exercise for Children

MedlinePlus

... time running and playing. Parents should limit TV, video game and computer time. Parents can set a good example by being active themselves. Exercising together can be fun for everyone. Competitive sports can help kids stay ...

Population Fisher information matrix and optimal design of discrete data responses in population pharmacodynamic experiments.

PubMed

Ogungbenro, Kayode; Aarons, Leon

2011-08-01

In the recent years, interest in the application of experimental design theory to population pharmacokinetic (PK) and pharmacodynamic (PD) experiments has increased. The aim is to improve the efficiency and the precision with which parameters are estimated during data analysis and sometimes to increase the power and reduce the sample size required for hypothesis testing. The population Fisher information matrix (PFIM) has been described for uniresponse and multiresponse population PK experiments for design evaluation and optimisation. Despite these developments and availability of tools for optimal design of population PK and PD experiments much of the effort has been focused on repeated continuous variable measurements with less work being done on repeated discrete type measurements. Discrete data arise mainly in PDs e.g. ordinal, nominal, dichotomous or count measurements. This paper implements expressions for the PFIM for repeated ordinal, dichotomous and count measurements based on analysis by a mixed-effects modelling technique. Three simulation studies were used to investigate the performance of the expressions. Example 1 is based on repeated dichotomous measurements, Example 2 is based on repeated count measurements and Example 3 is based on repeated ordinal measurements. Data simulated in MATLAB were analysed using NONMEM (Laplace method) and the glmmML package in R (Laplace and adaptive Gauss-Hermite quadrature methods). The results obtained for Examples 1 and 2 showed good agreement between the relative standard errors obtained using the PFIM and simulations. The results obtained for Example 3 showed the importance of sampling at the most informative time points. Implementation of these expressions will provide the opportunity for efficient design of population PD experiments that involve discrete type data through design evaluation and optimisation.

WJG sets an example of internationalization for other Chinese academic journals.

PubMed

Zu, Guang-An

2010-06-14

Supported by the "Special Fund for Key Academic Journals" of the National Natural Science Foundation of China, World Journal of Gastroenterology (WJG) has become a high-impact international clinical medical journal due to the great efforts of Professor Lian-Sheng Ma, Editor-in-Chief, and his team over several years. Now, WJG has successfully achieved a high degree of internationalization and sets a good example for other Chinese academic journals.

[Can tobacco companies be good corporate citizens?].

PubMed

Palazzo, G; Mena, S

2009-07-01

Tobacco companies have jumped on the Corporate social responsibility (CSR) bandwagon as a tentative to be societally accepted as responsible actors and good corporate citizens. This is however not possible for two reasons. First, the product they sell is lethal and thus not compatible with the precondition of doing no harm to be a good corporate citizen. Second, the behavior of tobacco firms is not responsible, being illustrated by four examples: junk science versus sound science strategy, seducing young smokers, political lobbying and getting customers on new markets. To conclude, three implications for regulating the activities of the tobacco industry are given.

Competitive Sports: Helping Kids Play it Cool

MedlinePlus

... make friends. But it's not always fun and games out on the field or court. The pressure ... good and bad stress simply by noticing kids' game-time interactions. For example, is your child focused ...

Child Nutrition: MedlinePlus Health Topic

MedlinePlus

... 10 Tips for Setting Good Examples (Department of Agriculture) - PDF Also in Spanish Better Nutrition Every Day: ... 10 Tips to Decrease Added Sugars (Department of Agriculture) - PDF Also in Spanish Feeding Your Child Athlete ( ...

Toddler Nutrition: MedlinePlus Health Topic

MedlinePlus

... in Spanish Healthy Eating for Preschoolers (Department of Agriculture) - PDF Also in Spanish Nutrition Guide for Toddlers ( ... 10 Tips for Setting Good Examples (Department of Agriculture) - PDF Also in Spanish Children's Nutrition: Tips for ...

Cholesterol Levels: What You Need to Know

MedlinePlus

... of saturated fats include some meats, dairy products, chocolate, baked goods, and deep-fried and processed foods. ... trans fats that you eat. Examples include the Therapeutic Lifestyle Changes diet and the DASH Eating Plan. ...

Good practices and health policy analysis in European sports stadia: results from the 'Healthy Stadia' project.

PubMed

Drygas, Wojciech; Ruszkowska, Joanna; Philpott, Matthew; Björkström, Olav; Parker, Mike; Ireland, Robin; Roncarolo, Federico; Tenconi, Maria

2013-06-01

Sport plays an important role within society and sports stadia provide significant settings for public health strategies. In addition to being places of mass gathering, stadia are often located in less affluent areas and are traditionally attended by 'harder to reach' communities. Unfortunately sports stadia and the clubs they host are rarely perceived as places that promote healthy lifestyles. Fast food, alcohol and tobacco are commonly advertized, served and consumed during sports games giving the spectators and TV fans contradictory messages concerning healthy choices. As part of a wider programme of work part-funded by the European Union, a study was therefore designed to explore current 'good practice' relating to positive health interventions in sports stadia across a number of European countries. Using a specially designed questionnaire, information about health policies and good practices relating to food offerings in stadia, physical activity promotion among local communities, tobacco policy, positive mental health initiatives, environmental sustainability practices and social responsibility policies were collected in 10 European countries (England and Northern Ireland, Finland, Georgia, Greece, Ireland, Italy, Latvia, Poland, Spain and Sweden) involving 88 stadia. The audit results show that stadia health policies differ considerably between specific countries and sports. Based on the literature analysed, the examples of good practices collected through the study, and the subsequent instigation of a European Healthy Stadia Network, it shows that there is considerable potential for stadia to become health promoting settings.

Numerical modeling of axi-symmetrical cold forging process by ``Pseudo Inverse Approach''

NASA Astrophysics Data System (ADS)

Halouani, A.; Li, Y. M.; Abbes, B.; Guo, Y. Q.

2011-05-01

The incremental approach is widely used for the forging process modeling, it gives good strain and stress estimation, but it is time consuming. A fast Inverse Approach (IA) has been developed for the axi-symmetric cold forging modeling [1-2]. This approach exploits maximum the knowledge of the final part's shape and the assumptions of proportional loading and simplified tool actions make the IA simulation very fast. The IA is proved very useful for the tool design and optimization because of its rapidity and good strain estimation. However, the assumptions mentioned above cannot provide good stress estimation because of neglecting the loading history. A new approach called "Pseudo Inverse Approach" (PIA) was proposed by Batoz, Guo et al.. [3] for the sheet forming modeling, which keeps the IA's advantages but gives good stress estimation by taking into consideration the loading history. Our aim is to adapt the PIA for the cold forging modeling in this paper. The main developments in PIA are resumed as follows: A few intermediate configurations are generated for the given tools' positions to consider the deformation history; the strain increment is calculated by the inverse method between the previous and actual configurations. An incremental algorithm of the plastic integration is used in PIA instead of the total constitutive law used in the IA. An example is used to show the effectiveness and limitations of the PIA for the cold forging process modeling.

Physicians' duties and the non-identity problem.

PubMed

Hope, Tony; McMillan, John

2012-01-01

The non-identity problem arises when an intervention or behavior changes the identity of those affected. Delaying pregnancy is an example of such a behavior. The problem is whether and in what ways such changes in identity affect moral considerations. While a great deal has been written about the non-identity problem, relatively little has been written about the implications for physicians and how they should understand their duties. We argue that the non-identity problem can make a crucial moral difference in some circumstances, and that it has some interesting implications for when it is or is not right for a physician to refuse to accede to a patient's request. If a physician is asked to provide an intervention (identity preserving) that makes a person worse off, then such harm provides a good reason for the physician to refuse to provide the intervention. However, in cases where different (identity-altering) interventions result in different people having a better or worse life, physicians should normally respect patient choice.

Linear and nonlinear response in sheared soft spheres

NASA Astrophysics Data System (ADS)

Tighe, Brian

2013-11-01

Packings of soft spheres provide an idealized model of foams, emulsions, and grains, while also serving as the canonical example of a system undergoing a jamming transition. Packings' mechanical response has now been studied exhaustively in the context of ``strict linear response,'' i.e. by linearizing about a stable static packing and solving the resulting equations of motion. Both because the system is close to a critical point and because the soft sphere pair potential is non-analytic at the point of contact, it is reasonable to ask under what circumstances strict linear response provides a good approximation to the actual response. We simulate sheared soft sphere packings close to jamming and identify two distinct strain scales: (i) the scale on which strict linear response fails, coinciding with a topological change in the packing's contact network; and (ii) the scale on which linear superposition of the averaged stress-strain curve breaks down. This latter scale provides a ``weak linear response'' criterion and is likely to be more experimentally relevant.

Porous Inorganic Drug Delivery Systems-a Review.

PubMed

Sayed, E; Haj-Ahmad, R; Ruparelia, K; Arshad, M S; Chang, M-W; Ahmad, Z

2017-07-01

Innovative methods and materials have been developed to overcome limitations associated with current drug delivery systems. Significant developments have led to the use of a variety of materials (as excipients) such as inorganic and metallic structures, marking a transition from conventional polymers. Inorganic materials, especially those possessing significant porosity, are emerging as good candidates for the delivery of a range of drugs (antibiotics, anticancer and anti-inflammatories), providing several advantages in formulation and engineering (encapsulation of drug in amorphous form, controlled delivery and improved targeting). This review focuses on key selected developments in porous drug delivery systems. The review provides a short broad overview of porous polymeric materials for drug delivery before focusing on porous inorganic materials (e.g. Santa Barbara Amorphous (SBA) and Mobil Composition of Matter (MCM)) and their utilisation in drug dosage form development. Methods for their preparation and drug loading thereafter are detailed. Several examples of porous inorganic materials, drugs used and outcomes are discussed providing the reader with an understanding of advances in the field and realistic opportunities.

Measure Guideline: Passive Vents

DOE Office of Scientific and Technical Information (OSTI.GOV)

Berger, David; Neri, Robin

2016-02-05

This document addresses the use of passive vents as a source of outdoor air in multifamily buildings. The challenges associated with implementing passive vents and the factors affecting performance are outlined. A comprehensive design methodology and quantified performance metrics are provided. Two hypothetical design examples are provided to illustrate the process. This document is intended to be useful to designers, decision-makers, and contractors implementing passive ventilation strategies. It is also intended to be a resource for those responsible for setting high-performance building program requirements, especially pertaining to ventilation and outdoor air. To ensure good indoor air quality, a dedicated sourcemore » of outdoor air is an integral part of high-performance buildings. Presently, there is a lack of guidance pertaining to the design and installation of passive vents, resulting in poor system performance. This report details the criteria necessary for designing, constructing, and testing passive vent systems to enable them to provide consistent and reliable levels of ventilation air from outdoors.« less

What kind of mentoring do we need? A review of mentoring program studies for medical students.

PubMed

Hur, Yera; Kim, Sun; Lee, Keumho

2013-03-01

Nearly every medical school in Korea has a student advisory program, regardless of its form or method, but it is plagued by efficiency. To examine efficient means of delivering student advisory programs, we chose 'mentoring' as one solution and reviewed the concepts of a mentor and mentoring, the qualities and roles of a mentor, and examples of national and international cases of mentoring. The concept of mentoring is diverse, but it connotes and stresses aspects, such as individual guidance, tutoring, life coaching, and role modeling. We conclude that the quality of many student advisory programs can be elevated by providing holistic and systematic guidance that meets the demands of the mentees; giving individual, continuous, and intimate coaching; and guiding a balanced academic and social life and career, which will develop good doctors who can provide a holistic health care.

Large Scale Production of Stem Cells and Their Derivatives

NASA Astrophysics Data System (ADS)

Zweigerdt, Robert

Stem cells have been envisioned to become an unlimited cell source for regenerative medicine. Notably, the interest in stem cells lies beyond direct therapeutic applications. They might also provide a previously unavailable source of valuable human cell types for screening platforms, which might facilitate the development of more efficient and safer drugs. The heterogeneity of stem cell types as well as the numerous areas of application suggests that differential processes are mandatory for their in vitro culture. Many of the envisioned applications would require the production of a high number of stem cells and their derivatives in scalable, well-defined and potentially clinical compliant manner under current good manufacturing practice (cGMP). In this review we provide an overview on recent strategies to develop bioprocesses for the expansion, differentiation and enrichment of stem cells and their progenies, presenting examples for adult and embryonic stem cells alike.

Geometrical optics approach in liquid crystal films with three-dimensional director variations.

PubMed

Panasyuk, G; Kelly, J; Gartland, E C; Allender, D W

2003-04-01

A formal geometrical optics approach (GOA) to the optics of nematic liquid crystals whose optic axis (director) varies in more than one dimension is described. The GOA is applied to the propagation of light through liquid crystal films whose director varies in three spatial dimensions. As an example, the GOA is applied to the calculation of light transmittance for the case of a liquid crystal cell which exhibits the homeotropic to multidomainlike transition (HMD cell). Properties of the GOA solution are explored, and comparison with the Jones calculus solution is also made. For variations on a smaller scale, where the Jones calculus breaks down, the GOA provides a fast, accurate method for calculating light transmittance. The results of light transmittance calculations for the HMD cell based on the director patterns provided by two methods, direct computer calculation and a previously developed simplified model, are in good agreement.

Balancing paediatric anaesthesia: preclinical insights into analgesia, hypnosis, neuroprotection, and neurotoxicity.

PubMed

Sanders, R D; Ma, D; Brooks, P; Maze, M

2008-11-01

Logistical and ethical reasons make conducting clinical research in paediatric practice difficult, and therefore safe and efficacious advances are dependent on good preclinical research. For example, notable advances have been made in preclinical studies of pain processing that correlate well with patient data. Other areas of paediatric anaesthetic research remain in their infancy including mechanisms of anaesthesia and anaesthetic neuroprotection and neurotoxicity. Animal data have identified the potential 'double-edged' sword of administering anaesthetic agents in the young; although these agents can be neuroprotective in certain circumstances, they can be neurotoxic in others. The potential for this toxicity must be balanced against the importance of providing adequate anaesthesia for which there can be no compromise. We review the current state of preclinical research in paediatric anaesthesia and identify areas which require further exploration in order to provide the foundations for well-conducted clinical trials.

Flow visualization methods for field test verification of CFD analysis of an open gloveport

DOE PAGES

Strons, Philip; Bailey, James L.

2017-01-01

Anemometer readings alone cannot provide a complete picture of air flow patterns at an open gloveport. Having a means to visualize air flow for field tests in general provides greater insight by indicating direction in addition to the magnitude of the air flow velocities in the region of interest. Furthermore, flow visualization is essential for Computational Fluid Dynamics (CFD) verification, where important modeling assumptions play a significant role in analyzing the chaotic nature of low-velocity air flow. A good example is shown Figure 1, where an unexpected vortex pattern occurred during a field test that could not have been measuredmore » relying only on anemometer readings. Here by, observing and measuring the patterns of the smoke flowing into the gloveport allowed the CFD model to be appropriately updated to match the actual flow velocities in both magnitude and direction.« less

Weighting the Parameters, a Response to Bancel׳s "Searching for Global Consciousness: A Seventeen Year Exploration".

PubMed

Nelson, Roger

This brief report is a response to the article by Peter Bancel entitled "Searching for Global Consciousness: A Seventeen Year Exploration" in which he compares a goal orientation (GO) model with a field-like model he refers to as global consciousness (GC). He first attempts to exclude the latter, and then presents selected tests that compare the models. While the article appears to provide support for Bancel׳s conclusion that GC cannot explain the data and must be supplanted by GO, there are good reasons to believe this conclusion is premature at best. I address the vulnerable assumptions underlying Bancel׳s rejection of GC, and then provide multiple examples of parametric structure in the data, which cannot be attributed to GO, but are amenable to explanation by field-like models. Copyright © 2017 Elsevier Inc. All rights reserved.

What’s Driving Uncertainty? The Model or the Model Parameters (What’s Driving Uncertainty? The influences of model and model parameters in data analysis)

DOE PAGES

Anderson-Cook, Christine Michaela

2017-03-01

Here, one of the substantial improvements to the practice of data analysis in recent decades is the change from reporting just a point estimate for a parameter or characteristic, to now including a summary of uncertainty for that estimate. Understanding the precision of the estimate for the quantity of interest provides better understanding of what to expect and how well we are able to predict future behavior from the process. For example, when we report a sample average as an estimate of the population mean, it is good practice to also provide a confidence interval (or credible interval, if youmore » are doing a Bayesian analysis) to accompany that summary. This helps to calibrate what ranges of values are reasonable given the variability observed in the sample and the amount of data that were included in producing the summary.« less

Two classes of bipartite networks: nested biological and social systems.

PubMed

Burgos, Enrique; Ceva, Horacio; Hernández, Laura; Perazzo, R P J; Devoto, Mariano; Medan, Diego

2008-10-01

Bipartite graphs have received some attention in the study of social networks and of biological mutualistic systems. A generalization of a previous model is presented, that evolves the topology of the graph in order to optimally account for a given contact preference rule between the two guilds of the network. As a result, social and biological graphs are classified as belonging to two clearly different classes. Projected graphs, linking the agents of only one guild, are obtained from the original bipartite graph. The corresponding evolution of its statistical properties is also studied. An example of a biological mutualistic network is analyzed in detail, and it is found that the model provides a very good fitting of all the main statistical features. The model also provides a proper qualitative description of the same features observed in social webs, suggesting the possible reasons underlying the difference in the organization of these two kinds of bipartite networks.

Resistance to bio-insecticides or how to enhance their sustainability: a review.

PubMed

Siegwart, Myriam; Graillot, Benoit; Blachere Lopez, Christine; Besse, Samantha; Bardin, Marc; Nicot, Philippe C; Lopez-Ferber, Miguel

2015-01-01

After more than 70 years of chemical pesticide use, modern agriculture is increasingly using biological control products. Resistances to conventional insecticides are wide spread, while those to bio-insecticides have raised less attention, and resistance management is frequently neglected. However, a good knowledge of the limitations of a new technique often provides greater sustainability. In this review, we compile cases of resistance to widely used bio-insecticides and describe the associated resistance mechanisms. This overview shows that all widely used bio-insecticides ultimately select resistant individuals. For example, at least 27 species of insects have been described as resistant to Bacillus thuringiensis toxins. The resistance mechanisms are at least as diverse as those that are involved in resistance to chemical insecticides, some of them being common to bio-insecticides and chemical insecticides. This analysis highlights the specific properties of bio-insecticides that the scientific community should use to provide a better sustainability of these products.

Cartesian Off-Body Grid Adaption for Viscous Time- Accurate Flow Simulation

NASA Technical Reports Server (NTRS)

Buning, Pieter G.; Pulliam, Thomas H.

2011-01-01

An improved solution adaption capability has been implemented in the OVERFLOW overset grid CFD code. Building on the Cartesian off-body approach inherent in OVERFLOW and the original adaptive refinement method developed by Meakin, the new scheme provides for automated creation of multiple levels of finer Cartesian grids. Refinement can be based on the undivided second-difference of the flow solution variables, or on a specific flow quantity such as vorticity. Coupled with load-balancing and an inmemory solution interpolation procedure, the adaption process provides very good performance for time-accurate simulations on parallel compute platforms. A method of using refined, thin body-fitted grids combined with adaption in the off-body grids is presented, which maximizes the part of the domain subject to adaption. Two- and three-dimensional examples are used to illustrate the effectiveness and performance of the adaption scheme.

The Hybrid Propellant Module (HPM): A New Concept for Space Transfer in the Earth's Neighborhood and Beyond

NASA Technical Reports Server (NTRS)

Mankins, John C.; Mazanek, Daniel D.

2001-01-01

The safe, affordable and effective transfer of ever-larger payloads and eventually personnel beyond Low Earth Orbit (LEO) is a major challenge facing future commercial development and human exploration of space. Without reusable systems, sustained exploration or large scale development beyond LEO appears to be economically non-viable. However, reusable systems must be capable of both good fuel efficiency and "high utilization of capacity", or else economic costs will remain unacceptably high. Various options exist that can provide high fuel efficiency - for example, Solar Electric Propulsion Systems (SEPS) - but only at the cost of low thrust and concomitant long transit times. Chemical propulsion systems offer the potential for high thrust and short transit times - including both cryogenic and non-cryogenic options - but only at the cost of relatively low specific impulse (Isp). Nuclear thermal propulsion systems offer relatively good thrust-to-weight and Isp - but involve public concerns that may be insurmountable for all except the most-critical of public purposes. Fixed infrastructures have been suggested as one approach to solving this challenge; for example, rotating tether approaches. However, these systems tend to suffer from high initial costs or unacceptable operational constraints. A new concept has been identified - the Hybrid Propellant Module (HPM) - that integrates the best features of both chemical and solar electric transportation architectures. The HPM approach appears to hold promise of solving the issues associated with other approaches, opening a new family of capabilities for future space exploration and development of near-Earth space and beyond. This paper provides a summary overview of the challenge of Earth neighborhood transportation and discusses how various systems concepts might be applied to meet the needs of these architectures. The paper describes a new approach, the HPM, and illustrates the application of the concept for a typical mission concept. The paper concludes with a discussion of needed technologies and a possible timeline for the development and evolution of this class of systems concepts.

New design for a rotatory joint actuator made with shape memory alloy contractile wire

NASA Astrophysics Data System (ADS)

Wang, Guoping; Shahinpoor, Mohsen

1996-05-01

A design approach for a rotatory joint actuator using a contractile shape memory alloy (SMA) wire is presented and an example design is followed. In this example, the output torque of the actuator is 18 Newton-meters, and its angular range is 30 degrees. Compared with a SMA spring type actuating component, a SMA wire type actuating component uses less SMA material and uses less electrical energy when it is electrically powered. On the other hand, a SMA wire type actuating component must have a large SMA wire length to produce a required amount of angular rotation of the joint. When pulleys are used to arrange a lengthy SMA wire in a small space, the friction between pulleys and pins is introduced and the performance of the joint actuator is degenerated to some degree. The investigated joint actuator provides a good chance for developing powered orthoses with SMA actuators for disabled individuals. It can relieve the weight concern with hydraulic and motor-powered orthoses and the safety concern with motor-powered orthoses. When electrically powered, a SMA actuator has the disadvantage of low energy efficiency.

Power Management for Space Advanced Life Support

NASA Technical Reports Server (NTRS)

Jones, Harry

2001-01-01

Space power systems include the power source, storage, and management subsystems. In current crewed spacecraft, solar cells are the power source, batteries provide storage, and the crew performs any required load scheduling. For future crewed planetary surface systems using Advanced Life Support, we assume that plants will be grown to produce much of the crew's food and that nuclear power will be employed. Battery storage is much more costly than nuclear power capacity and so is not likely to be used. We investigate the scheduling of power demands by the crew or automatic control, to reduce the peak power load and the required generating capacity. The peak to average power ratio is a good measure of power use efficiency. We can easily schedule power demands to reduce the peak power from its maximum, but simple scheduling approaches may not find the lowest possible peak to average power ratio. An initial power scheduling example was simple enough for a human to solve, but a more complex example with many intermittent load demands required automatic scheduling. Excess power is a free resource and can be used even for minor benefits.

A Pipeline for Large Data Processing Using Regular Sampling for Unstructured Grids

DOE Office of Scientific and Technical Information (OSTI.GOV)

Berres, Anne Sabine; Adhinarayanan, Vignesh; Turton, Terece

2017-05-12

Large simulation data requires a lot of time and computational resources to compute, store, analyze, visualize, and run user studies. Today, the largest cost of a supercomputer is not hardware but maintenance, in particular energy consumption. Our goal is to balance energy consumption and cognitive value of visualizations of resulting data. This requires us to go through the entire processing pipeline, from simulation to user studies. To reduce the amount of resources, data can be sampled or compressed. While this adds more computation time, the computational overhead is negligible compared to the simulation time. We built a processing pipeline atmore » the example of regular sampling. The reasons for this choice are two-fold: using a simple example reduces unnecessary complexity as we know what to expect from the results. Furthermore, it provides a good baseline for future, more elaborate sampling methods. We measured time and energy for each test we did, and we conducted user studies in Amazon Mechanical Turk (AMT) for a range of different results we produced through sampling.« less

Patient autonomy and choice in healthcare: self-testing devices as a case in point.

PubMed

Greaney, Anna-Marie; O'Mathúna, Dónal P; Scott, P Anne

2012-11-01

This paper aims to critique the phenomenon of advanced patient autonomy and choice in healthcare within the specific context of self-testing devices. A growing number of self-testing medical devices are currently available for home use. The premise underpinning many of these devices is that they assist individuals to be more autonomous in the assessment and management of their health. Increased patient autonomy is assumed to be a good thing. We take issue with this assumption and argue that self-testing provides a specific example how increased patient autonomy and choice within healthcare might not best serve the patient population. We propose that current interpretations of autonomy in healthcare are based on negative accounts of liberty to the detriment of a more relational understanding. We also propose that Kantian philosophy is often applied to the healthcare arena in an inappropriate manner. We draw on the philosophical literature and examples from the self-testing process to support these claims. We conclude by offering an alternative account of autonomy based on the interrelated concepts of relationality, care and responsibility.

Optimization strategy for and structural properties of traffic efficiency under bounded information accessibility

NASA Astrophysics Data System (ADS)

Sanghyun, Ahn; Seungwoong, Ha; Kim, Soo Yong

2016-06-01

A vital challenge for many socioeconomic systems is determining the optimum use of limited information. Traffic systems, wherein the range of resources is limited, are a particularly good example of this challenge. Based on bounded information accessibility in terms of, for example, high costs or technical limitations, we develop a new optimization strategy to improve the efficiency of a traffic system with signals and intersections. Numerous studies, including the study by Chowdery and Schadschneider (whose method we denote by ChSch), have attempted to achieve the maximum vehicle speed or the minimum wait time for a given traffic condition. In this paper, we introduce a modified version of ChSch with an independently functioning, decentralized control system. With the new model, we determine the optimization strategy under bounded information accessibility, which proves the existence of an optimal point for phase transitions in the system. The paper also provides insight that can be applied by traffic engineers to create more efficient traffic systems by analyzing the area and symmetry of local sites. We support our results with a statistical analysis using empirical traffic data from Seoul, Korea.

Refining glass structure in two dimensions

NASA Astrophysics Data System (ADS)

Sadjadi, Mahdi; Bhattarai, Bishal; Drabold, D. A.; Thorpe, M. F.; Wilson, Mark

2017-11-01

Recently determined atomistic scale structures of near-two dimensional bilayers of vitreous silica (using scanning probe and electron microscopy) allow us to refine the experimentally determined coordinates to incorporate the known local chemistry more precisely. Further refinement is achieved by using classical potentials of varying complexity: one using harmonic potentials and the second employing an electrostatic description incorporating polarization effects. These are benchmarked against density functional calculations. Our main findings are that (a) there is a symmetry plane between the two disordered layers, a nice example of an emergent phenomena, (b) the layers are slightly tilted so that the Si-O-Si angle between the two layers is not 180∘ as originally thought but rather 175 ±2∘ , and (c) while interior areas that are not completely imagined can be reliably reconstructed, surface areas are more problematic. It is shown that small crystallites that appear are just as expected statistically in a continuous random network. This provides a good example of the value that can be added to disordered structures imaged at the atomic level by implementing computer refinement.

An introgressed wing pattern acts as a mating cue.

PubMed

Sánchez, Angela P; Pardo-Diaz, Carolina; Enciso-Romero, Juan; Muñoz, Astrid; Jiggins, Chris D; Salazar, Camilo; Linares, Mauricio

2015-06-01

Heliconius butterflies provide good examples of both homoploid hybrid speciation and ecological speciation. In particular, examples of adaptive introgression have been detected among the subspecies of Heliconius timareta, which acquired red color pattern elements from H. melpomene. We tested whether the introgression of red wing pattern elements into H. timareta florencia might also be associated with incipient reproductive isolation (RI) from its close relative, H. timareta subsp. nov., found in the eastern Andes. No choice experiments show a 50% reduction in mating between females of H. t. subsp. nov. and males of H .t. florencia, but not in the reciprocal direction. In choice experiments using wing models, males of H. timareta subsp. nov. approach and court red phenotypes less than their own, whereas males of H. t. florencia prefer models with a red phenotype. Intrinsic postzygotic isolation was not detected in crosses between these H. timareta races. These results suggest that a color pattern trait gained by introgression is triggering RI between H. timareta subsp. nov. and H. t. florencia. © 2015 The Author(s). Evolution © 2015 The Society for the Study of Evolution.

The Application of Statistical Process Control in Non-Manufacturing Activities

DTIC Science & Technology

1988-01-01

food and lodging, legal, medical, fin- ancial, communication, engineering, architecture, and consultation. Also included would be education...sequence of pro- duction events and an output that is a product or the completion of a 9 service. A good example of this is a fast food restaurant. A...of quality improvement, and how they relate to each other. In discussing the definition of quality, the character- istics of both good and bad

How to get the customer service your practice deserves.

PubMed

Cavallo, Nancy

2009-01-01

What is good customer service, and how can office managers and others who deal with medical supply distributors get the customer service they deserve? This article covers the basics of good customer service, including examples of companies known for putting the customer first-Nordstrom, Disney, Johnson &Johnson, and VaxServe. Helpful tips on what to look for in a distributor include personalized service, cost considerations, dedication, knowledge, experience, helpfulness, openness, reliability, and compatibility.

The Shock and Vibration Digest. Volume 14. Number 3

DTIC Science & Technology

1982-03-01

for torsional natural frequencies are good example of techniques that have been programmed on small calculators. Recently, in fact, a short paper...obtained and controlled by hydrostatic or hydrodynamic lift. It is important to keep the mating faces as parallel as possible; hence, good tracking...25. Crandall, S.H., "Physical Explanations of the Destabilizing Effect of Damping in Rotating Parts." ibid.. pp 369-382 (1980). 18 ., iA .^., . .J

Officer Performance Appraisal in the Coast Guard: An Analysis of the Fitness Reporting System.

DTIC Science & Technology

1979-12-01

organizational settings has also received substantial attention in the research literature (Lawler, 1970; Luthans and Kreitner, 1975; Opsahl and Dunnette...16/78 177 13. Inspires respect of his 13. Does not inspire confi- subordinates. dence in subordinates. 14. Works well under pressure. 14. May burn...aggressive, and a good leader ." "This officer is very capable, handling his assigned duties conscientiously and willingly. Sets a good example in

Snapshots: Marimba Magic; Rediscovering Coyote and Raven; New Life for an Old War; Good Health, Good Heart; Winds of Change; What the Forest Gives; Lessons in the Loop; a Talking Book.

ERIC Educational Resources Information Center

Reed, Bracken; Linik, Joyce Riha; Muir, Maya; Fisher, Amy

2002-01-01

Applications of project-based learning are illustrated by examples of projects involving music, art, history, a partnership with a hospital, Native American plant remedies, roller coaster design, and making a "talking book" (CD-ROM) in English and Lushootseed (language of the Tulalip Tribes). Project learning can meet standards while involving…

Geoheritage Values at Greenmantle Farm

NASA Astrophysics Data System (ADS)

Etches, J. D.

2009-05-01

The Greenmantle Farm occurrence near Wilberforce, Ontario is a marble feature within the Grenville Province of the Precambrian Shield that hosts a diverse suite of amphibole minerals. The marble is of undetermined petrogenesis, and is possibly either a primary carbonatite intrusion or a derived melt of metasedimentary origin. The site is the type locality for the rare mineral fluorrichterite. Other minerals of note are orthoclase and apatite. Crystal size is relatively large, and all minerals, with the exception of calcite, exhibit generally good to excellent euhedral form. Of note is that the mineral occurrences at this site have not been subjected to any human disturbance including mechanical or hand tool disruption. The site also provides excellent examples of a number of geological features and ecosystem dynamics. In particular, faulting, moisture regime landscape interrelationships, order of crystallization in zoned dykes, and calciphile plant associations are demonstrated. This site represents an exceptional viewing opportunity of an unspoiled mineral occurrence while providing illustrative examples of the interrelationship of abiotic and biotic features. In terms of research, the site will prove to be a valuable subject in regard to amphibole composition, amphibole differentiation in calcareous melts, and will ultimately provide insight into the formation of the occurrence. Determination of what circumstances these marble bodies formed under would add a significant piece of information to the complex history of the Grenville province. This research will be assisted by the completely uncompromised nature of the site. The potential educational value of the site for researchers and grade school students alike is exceptional.

Functional architecture of visual emotion recognition ability: A latent variable approach.

PubMed

Lewis, Gary J; Lefevre, Carmen E; Young, Andrew W

2016-05-01

Emotion recognition has been a focus of considerable attention for several decades. However, despite this interest, the underlying structure of individual differences in emotion recognition ability has been largely overlooked and thus is poorly understood. For example, limited knowledge exists concerning whether recognition ability for one emotion (e.g., disgust) generalizes to other emotions (e.g., anger, fear). Furthermore, it is unclear whether emotion recognition ability generalizes across modalities, such that those who are good at recognizing emotions from the face, for example, are also good at identifying emotions from nonfacial cues (such as cues conveyed via the body). The primary goal of the current set of studies was to address these questions through establishing the structure of individual differences in visual emotion recognition ability. In three independent samples (Study 1: n = 640; Study 2: n = 389; Study 3: n = 303), we observed that the ability to recognize visually presented emotions is based on different sources of variation: a supramodal emotion-general factor, supramodal emotion-specific factors, and face- and within-modality emotion-specific factors. In addition, we found evidence that general intelligence and alexithymia were associated with supramodal emotion recognition ability. Autism-like traits, empathic concern, and alexithymia were independently associated with face-specific emotion recognition ability. These results (a) provide a platform for further individual differences research on emotion recognition ability, (b) indicate that differentiating levels within the architecture of emotion recognition ability is of high importance, and (c) show that the capacity to understand expressions of emotion in others is linked to broader affective and cognitive processes. (c) 2016 APA, all rights reserved).

Best practice in smoking cessation services for pregnant women: results of a survey of three services reporting the highest national returns, and three beacon services.

PubMed

Lee, Michelle; Hajek, Peter; McRobbie, Hayden; Owen, Lesley

2006-09-01

The NHS allocated dedicated funds to establish specialist smoking cessation services for pregnant smokers in England in 2000. An early survey revealed some uncertainty as to how the new services should work and monitor their outcome. The current survey focused on identifying examples of good practice in this difficult new field. Three services with the highest number of successful four-week quitters reported for the 2003/4 monitoring year were identified from Department of Health (DH) monitoring records, and three services were nominated from those known in the field as examples of best practice. There was no overlap between the two groups. All six services provided in-depth interviews. All three highest ranking services that reported close to 100 per cent success rates included unaided quitters identified from hospital wards, rather then smokers actually treated. They had only minimal or average genuine treatment provision for pregnant smokers in place. The three beacon services far exceeded the national throughput and outcome average identified in the previous survey, and provided a wealth of useful information. Although they differed in staffing levels and other aspects of their activities, they all shared several key elements, including a systematic training of midwives in how to refer pregnant smokers, offering nicotine replacement treatment to almost all clients and having an efficient system of providing the prescriptions, offering flexible home visits, and providing intensive multi-session treatment delivered by a small number of dedicated staff. Smoking cessation services for pregnant women may need clearer guidance on what they are expected to provide, and how they should monitor their outcome. The key features of the beacon services can serve as a practical model of current best practice applicable across most PCTs.

WJG sets an example of internationalization for other Chinese academic journals

PubMed Central

Zu, Guang-An

2010-01-01

Supported by the “Special Fund for Key Academic Journals” of the National Natural Science Foundation of China, World Journal of Gastroenterology (WJG) has become a high-impact international clinical medical journal due to the great efforts of Professor Lian-Sheng Ma, Editor-in-Chief, and his team over several years. Now, WJG has successfully achieved a high degree of internationalization and sets a good example for other Chinese academic journals. PMID:20533589

The Size and Role of Government: Economic Issues

DTIC Science & Technology

2009-07-01

results in a net loss in economic efficiency over time. 32 See, for example, N. Gregory Mankiw , Principles of Microeconomics (Fort Worth: Dryden Press...Act of 1986 (P.L. 99-514) as a good example of a tax reform that followed this principle . The Size and Role of Government: Economic Issues...sacrifice principle that tax rates should be set by income status such that taxes reduce the welfare of all taxpayers equally (so that high income

Infusing Personal Responsibility into the Curriculum and Cocurriculum: Campus Examples

ERIC Educational Resources Information Center

O'Neill, Nancy

2013-01-01

This chapter highlights good practices and lessons learned for infusing personal responsibility--striving for excellence, cultivating academic integrity, and developing competence in ethical and moral reasoning and action--as outcomes of college.

Improving patient safety and healthcare quality: examples of good practice.

PubMed

Tingle, John

2017-07-27

John Tingle, Reader in Health Law at Nottingham Trent University, discusses a recent report by the Care Quality Commission that showcases eight NHS trusts that have improved their patient safety and healthcare quality.

Serving Agriculture's "Big Business"

ERIC Educational Resources Information Center

Schake, L. M.

1970-01-01

A new dimension and challenge in Extension activities is emerging as some phases of agriculture evolve from small operations to multimillion dollar agribusiness ventures; the beef cattle commercial feedlot industry in the Southwest is a good example. (EB)

Wastewater Plant Operation and Maintenance--A Matter of Growing Concern

ERIC Educational Resources Information Center

Water and Wastes Engineering, 1978

1978-01-01

Responses of two experts to questions concerning wastewater plant operation and maintenance are presented. The responses discuss the scarcity of good personnel, training education available, and examples of existing improvement projects. (MA)

Assessment of system reliability for a stochastic-flow distribution network with the spoilage property

NASA Astrophysics Data System (ADS)

Lin, Yi-Kuei; Huang, Cheng-Fu; Yeh, Cheng-Ta

2016-04-01

In supply chain management, satisfying customer demand is the most concerned for the manager. However, the goods may rot or be spoilt during delivery owing to natural disasters, inclement weather, traffic accidents, collisions, and so on, such that the intact goods may not meet market demand. This paper concentrates on a stochastic-flow distribution network (SFDN), in which a node denotes a supplier, a transfer station, or a market, while a route denotes a carrier providing the delivery service for a pair of nodes. The available capacity of the carrier is stochastic because the capacity may be partially reserved by other customers. The addressed problem is to evaluate the system reliability, the probability that the SFDN can satisfy the market demand with the spoilage rate under the budget constraint from multiple suppliers to the customer. An algorithm is developed in terms of minimal paths to evaluate the system reliability along with a numerical example to illustrate the solution procedure. A practical case of fruit distribution is presented accordingly to emphasise the management implication of the system reliability.

Self-determination vs. family-determination: two incommensurable principles of autonomy: a report from East Asia.

PubMed

Fan, Ruiping

1997-01-01

Most contemporary bioethicists believe that Western bioethical principles, such as the principle of autonomy, are universally binding wherever bioethics is found. According to these bioethicists, these principles may be subject to culturally-conditioned further interpretations for their application in different nations or regions, but an 'abstract content' of each principle remains unchanged, which provides 'an objective basis for moral judgment and international law'. This essay intends to demonstrate that this is not the case. Taking the principle of autonomy as an example, this essay argues that there is no such shared 'abstract content' between the Western bioethical principle of autonomy and the East Asian bioethical principle of autonomy. Other things being equal, the Western principle of autonomy demands self-determination, assumes a subjective conception of the good and promotes the value of individual independence, whilst the East Asian principle of autonomy requires family-determination, presupposes an objective conception of the good and upholds the value of harmonious dependence. They differ from each other in the most general sense and basic moral requirement.

A chi-square goodness-of-fit test for non-identically distributed random variables: with application to empirical Bayes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Conover, W.J.; Cox, D.D.; Martz, H.F.

1997-12-01

When using parametric empirical Bayes estimation methods for estimating the binomial or Poisson parameter, the validity of the assumed beta or gamma conjugate prior distribution is an important diagnostic consideration. Chi-square goodness-of-fit tests of the beta or gamma prior hypothesis are developed for use when the binomial sample sizes or Poisson exposure times vary. Nine examples illustrate the application of the methods, using real data from such diverse applications as the loss of feedwater flow rates in nuclear power plants, the probability of failure to run on demand and the failure rates of the high pressure coolant injection systems atmore » US commercial boiling water reactors, the probability of failure to run on demand of emergency diesel generators in US commercial nuclear power plants, the rate of failure of aircraft air conditioners, baseball batting averages, the probability of testing positive for toxoplasmosis, and the probability of tumors in rats. The tests are easily applied in practice by means of corresponding Mathematica{reg_sign} computer programs which are provided.« less

A comprehensive clinical assessment tool to inform policy and practice: applications of the minimum data set.

PubMed

Mor, Vincent

2004-04-01

The Minimum Data Set (MDS) for nursing home (NH) resident assessment, designed to assess elders functional status and care needs, exemplifies how the information needs of clinical practice are congruent with those of research. Building on a review of the published literature, this article describes the development of the MDS, its reliability and validity testing, as well as the variety of different policy and research uses to which it has been applied. Interrater reliability of items and internal consistency of MDS summary scales is generally good to excellent. Validation studies reveal good correspondence to research quality instruments for cognition, activities of daily living, and diagnoses with more variable results for vision, pain, mood, and behavior scales. To date, no consistent evidence suggests that applications of MDS data for case-mix reimbursement and quality indicator monitoring systematically bias the data. Although facility variation in data quality could compromise some applications, creation of the MDS as a clinical tool for care planning provides an example of how assessment tools with clinical use can be used in administrative databases for research and policy applications.

[Institutional violence, medical authority, and power relations in maternity hospitals from the perspective of health workers].

PubMed

Aguiar, Janaina Marques de; d'Oliveira, Ana Flávia Pires Lucas; Schraiber, Lilia Blima

2013-11-01

The current article discusses institutional violence in maternity hospitals from the health workers' perspective, based on data from a study in the city of São Paulo, Brazil. Eighteen health workers from the public and private sectors were interviewed, including obstetricians, nurses, and nurse technicians. A semi-structured interview was used with questions on professional experience and the definition of violence. The analysis revealed that these health workers acknowledged the existence of discriminatory and disrespectful practices against women during prenatal care, childbirth, and the postpartum. Examples of such practices cited by interviewees included the use of pejorative slang as a form of "humor", threats, reprimands, and negligence in the management of pain. Such practices are not generally viewed by health workers as violent, but rather as the exercise of professional authority in what is considered a "difficult" context. The institutional violence is thus trivialized, disguised as purportedly good practice (i.e., "for the patient's own good"), and rendered invisible in the daily routine of care provided by maternity services.

Genetics and Psychopharmacology: Prospects for Individualized Treatment

PubMed Central

Nnadi, Charles U.; Goldberg, Joseph F.; Malhotra, Anil K.

2008-01-01

This article provides a clear and succinct description of the components of inheritance, such as trait transmission, genetic variability, and gene interaction. Genetic sequences constitute the prime focus of pharmacogenetic studies. Variations in drug-metabolizing enzyme systems tend to be monogenic, whereas the pharmacologic effects of medications appear to be polygenic, i.e., complex phenotypes shaped by the interaction of genes and environment. Translated into clinical terms, a history of a good response to a drug in a close relative of a patient is presumed to indicate a good response to the same medication by the patient. This seems to hold for antidepressants, antipsychotics, and lithium, but the evidential studies generally have meaningful limitations. Bit by bit, information about the relationship between particular genetic formations and the effectiveness of these medications as well as their side effects, is appearing. The authors cite a number of examples, one such being an association between impaired antidepressant activity and the short allele of SLC6A4. This research promises to strengthen the accuracy, effectiveness, safety, and cost of our psychopharmacological practices. PMID:16041916

Genetics and psychopharmacology: prospects for individualized treatment.

PubMed

Nnadi, Charles U; Goldberg, Joseph F; Malhotra, Anil K

2005-01-01

This article provides a clear and succinct description of the components of inheritance, such as trait transmission, genetic variability, and gene interaction. Genetic sequences constitute the prime focus of pharmacogenetic studies. Variations in drug-metabolizing enzyme systems tend to be monogenic, whereas the pharmacologic effects of medications appear to be polygenic, i.e., complex phenotypes shaped by the interaction of genes and environment. Translated into clinical terms, a history of a good response to a drug in a close relative of a patient is presumed to predict a good response to the same medication by the patient. This seems to hold for antidepressants, antipsychotics, and lithium, but the evidential studies generally have meaningful limitations. Bit by bit, information about the relationship between particular genetic formations and the effectiveness of these medications as well as their side effects, is appearing. The authors cite a number of examples, one such being an association between impaired antidepressant activity and the short allele of SLC6A4. This research promises to strengthen the accuracy, effectiveness, safety, and cost of our psychopharmacological practices.

A rational account of pedagogical reasoning: teaching by, and learning from, examples.

PubMed

Shafto, Patrick; Goodman, Noah D; Griffiths, Thomas L

2014-06-01

Much of learning and reasoning occurs in pedagogical situations--situations in which a person who knows a concept chooses examples for the purpose of helping a learner acquire the concept. We introduce a model of teaching and learning in pedagogical settings that predicts which examples teachers should choose and what learners should infer given a teacher's examples. We present three experiments testing the model predictions for rule-based, prototype, and causally structured concepts. The model shows good quantitative and qualitative fits to the data across all three experiments, predicting novel qualitative phenomena in each case. We conclude by discussing implications for understanding concept learning and implications for theoretical claims about the role of pedagogy in human learning. Copyright © 2014 Elsevier Inc. All rights reserved.

Foveated optics

NASA Astrophysics Data System (ADS)

Bryant, Kyle R.

2016-05-01

Foveated imaging can deliver two different resolutions on a single focal plane, which might inexpensively allow more capability for military systems. The following design study results provide starting examples, lessons learned, and helpful setup equations and pointers to aid the lens designer in any foveated lens design effort. Our goal is to put robust sensor in a small package with no moving parts, but still be able to perform some of the functions of a sensor in a moving gimbal. All of the elegant solutions are out (for various reasons). This study is an attempt to see if lens designs can solve this problem and realize some gains in performance versus cost for airborne sensors. We determined a series of design concepts to simultaneously deliver wide field of view and high foveal resolution without scanning or gimbals. Separate sensors for each field of view are easy and relatively inexpensive, but lead to bulky detectors and electronics. Folding and beam-combining of separate optical channels reduces sensor footprint, but induces image inversions and reduced transmission. Entirely common optics provide good resolution, but cannot provide a significant magnification increase in the foveal region. Offsetting the foveal region from the wide field center may not be physically realizable, but may be required for some applications. The design study revealed good general guidance for foveated optics designs with a cold stop. Key lessons learned involve managing distortion, telecentric imagers, matching image inversions and numerical apertures between channels, reimaging lenses, and creating clean resolution zone splits near internal focal planes.

A systematic molecular dynamics approach to the study of peptide Keap1-Nrf2 protein-protein interaction inhibitors and its application to p62 peptides.

PubMed

Lu, Meng-Chen; Yuan, Zhen-Wei; Jiang, Yong-Lin; Chen, Zhi-Yun; You, Qi-Dong; Jiang, Zheng-Yu

2016-04-01

Protein-protein interactions (PPIs) as drug targets have been gaining growing interest, though developing drug-like small molecule PPI inhibitors remains challenging. Peptide PPI inhibitors, which can provide informative data on the PPI interface, are good starting points to develop small molecule modulators. Computational methods combining molecular dynamics simulations and binding energy calculations could give both the structural and the energetic perspective of peptide PPI inhibitors. Herein, we set up a computational workflow to investigate Keap1-Nrf2 peptide PPI inhibitors and predict the activity of novel sequences. Furthermore, we applied this method to investigate p62 peptides as PPI inhibitors of Keap1-Nrf2 and explored the activity change induced by the phosphorylation of serine. Our results showed that because of the unfavorable solvation effects, the binding affinity of the phosphorylated p62 peptide is lower than the Nrf2 ETGE peptide. Our research results not only provide a useful method to investigate the Keap1-Nrf2 peptide inhibitors, but also give a good example to show how to incorporate computational methods into the study of peptide PPI inhibitors. Besides, applying this method to p62 peptides provides a detailed explanation for the expression of cytoprotective Nrf2 targets induced by p62 phosphorylation, which may benefit the further study of the crosstalk between the Keap1-Nrf2 pathway and p62-mediated selective autophagy.

Application of large-area chromogenics to architectural glazings

NASA Astrophysics Data System (ADS)

Selkowitz, Stephen E.

1990-03-01

Glass plays a significant role in the design of building envelopes today. Since its emergence during the last century as a major building material, glass has evolved into an ubiquitous and versatile building design element, performing functions today that would have been unimaginable a few years ago. The optical clarity and transparency of glass that we take for granted is one of its most unique features. Glass windows keep out the cold wind and rain without blocking the view, but also perform many more complex functions which require variable properties and tradeoffs between conflicting conditions. The glazing that provides view must also provide visual privacy at other times and must sometimes become totally opaque (for audiovisual shows, for example). Transparent glass admits daylight, providing good color rendition and offsetting electric lighting energy needs, but it can also create discomfort and disability glare conditions. The sun provides desirable warmth in winter but its heat is unwelcome in summer when it contributes to thermal discomfort and cooling energy requirements. And glass is an important element in the appearance and aesthetics of a building, both interior and exterior.

Neuroeconomics: in search of the neural representation of brands.

PubMed

Schaefer, Michael

2009-01-01

In modern economy the customer is confronted with a huge amount of consumer goods. In this situation, culturally based brands seem to play an important role in establishing strong emotional bonds between customers and goods and to guide people's economic behavior by biasing selections and preference decisions based on affect. Recently, neuroscientific approaches have demonstrated that cultural objects like brands or brand-related behavior may successfully be investigated with neuroimaging tools like fMRI. First studies suggested that structures associated with the reward circuit (striatum) and the dorsolateral part of the prefrontal cortex may be involved when perceiving a favorite brand. Hence, brands that have been associated with appetitive stimuli due to marketing efforts or cultural factors seem to engage similar brain networks than artificially associated reward stimuli. However, brands have different and complex meanings in our life far beyond representing objects of desire. For example, the possession of goods from certain kinds of brands often is used to mark the social state of the owner and to distinguish him or her from other groups. In particular, luxury goods often seem to have this function. Recent neuroimaging results support this observation by showing that viewing logos of luxury brands is associated with brain activity in the anterior medial prefrontal cortex, a region known to be associated with self-centered cognitions. Thus, it seems that brands of luxury goods improve self-relevant thoughts, pointing to the role of luxury brands to mark the superior position of the owner in society. These results demonstrate that cultural symbols like brands can successfully be examined with neuroimaging approaches. Thus, along with advanced cultural theories, neuroeconomics may provide important contributions to the understanding of brand-related or economic behavior.

The Use of Human Modeling of EVA Tasks as a Systems Engineering Tool

NASA Technical Reports Server (NTRS)

Dischinger, H. Charles, Jr.; Schmidt, Henry J.; Kross, Dennis A. (Technical Monitor)

2001-01-01

Computer-generated human models have been used in aerospace design for a decade. They have come to be highly reliable for worksite analysis of certain types of EVA tasks. In many design environments, this analysis comes after the structural design is largely complete. However, the use of these models as a development tool is gaining acceptance within organizations that practice good systems engineering processes. The design of the United States Propulsion Module for the International Space Station provides an example of this application. The Propulsion Module will provide augmentation to the propulsion capability supplied by the Russian Service Module Zvezda. It is a late addition to the set of modules provided by the United States to the ISS Program, and as a result, faces design challenges that result from the level of immaturity of its integration into the Station. Among these are heat dissipation and physical envelopes. Since the rest of the Station was designed to maximize the use of the cooling system, little margin is available for the addition of another module. The Propulsion Module will attach at the forward end of the Station, and will be between the Orbiter and the rest of ISS. Since cargo must be removed from the Payload Bay and transferred to Station by the Canadarm, there is a potential for protrusions from the module, such as thruster booms, to interfere with robotic operations. These and similar engineering issues must be addressed as part of the development. In the implementation of good system design, all design solutions should be analyzed for compatibility with all affected subsystems. Human modeling has been used in this project to provide rapid input to system trades of design concepts. For example, the placement of radiators and avionics components for optimization of heat dissipation had to be examined for feasibility of EVA translation paths and worksite development. Likewise, the location of and mechanism for the retraction of thruster booms was partly driven by available Orbiter, robotic arm, and other module envelopes; worksite analysis was required for early assessment of task success. Since these trade studies included the EVA analysis as part of the decision criteria, the design had a high degree of assurance of EVA supportability from the outset. This approach contributes greatly to mission success.

Target community foundations to fund family planning.

PubMed

1994-04-01

Practical advice was given on how to secure funding for privately sponsored US family planning programs in local communities. The first step is in identifying community foundations that are directly involved in social service delivery in the local area. For example, Norplant kits were made available to low-income women through a grant from the Baltimore-based Abell Foundation. Another example is that local funds were used to produce a Norplant video, which was needed for outreach programs and for explaining the pros and cons of Norplant use. The short video was designed for multiple audiences, even though it was locally produced and funded in Baltimore. Sometimes the health department can create a consortium of providers for applying for a group grant. The Foundation Center in New York provides information on foundations, including state-by-state analysis of foundations and family planning funded projects. The Foundation Directory and Grants Index publishes by subject a list of foundations funding such areas. These publications are available in network or local libraries. Background information needs to be obtained on the guidelines required for applying for a specific foundation's grant; guidelines may vary widely between foundations and have strict or loose restrictions on form and substance. An important initial step is writing a very brief synthesis of your proposal (2 pages), if there is no prior knowledge of the receptivity of the foundation to the proposed program. If the project is within the scope of the foundation, a larger formal proposal is the next step. Foundations want to see well through out projects, budgeted carefully, with evaluation components. Examples of successful projects conducted elsewhere are good testimonials to the potential success of the proposed venture. Cultural acceptance in the community, pilot projects replicable in other areas, and target populations are important considerations to be included in the proposal.

Introduced and invasive species in novel rangeland ecosystems: friends or foes?

USGS Publications Warehouse

Belnap, Jayne; Ludwig, John A.; Wilcox, Bradford P.; Betancourt, Julio L.; Dean, W. Richard J.; Hoffmann, Benjamin D.; Milton, Sue J.

2012-01-01

Globally, new combinations of introduced and native plant and animal species have changed rangelands into novel ecosystems. Whereas many rangeland stakeholders (people who use or have an interest in rangelands) view intentional species introductions to improve forage and control erosion as beneficial, others focus on unintended costs, such as increased fire risk, loss of rangeland biodiversity, and threats to conservation efforts, specifically in nature reserves and parks. These conflicting views challenge all rangeland stakeholders, especially those making decisions on how best to manage novel ecosystems. To formulate a conceptual framework for decision making, we examined a wide range of novel ecosystems, created by intentional and unintentional introductions of nonnative species and land-use–facilitated spread of native ones. This framework simply divides decision making into two types: 1) straightforward–certain, and 2) complex–uncertain. We argue that management decisions to retain novel ecosystems are certain when goods and services provided by the system far outweigh the costs of restoration, for example in the case of intensively managed Cenchrus pastures. Decisions to return novel ecosystems to natural systems are also certain when the value of the system is low and restoration is easy and inexpensive as in the case of biocontrol of Opuntia infestations. In contrast, decisions whether to retain or restore novel ecosystems become complex and uncertain in cases where benefits are low and costs of control are high as, for example, in the case of stopping the expansion of Prosopis and Juniperus into semiarid rangelands. Decisions to retain or restore novel ecosystems are also complex and uncertain when, for example, nonnative Eucalyptus trees expand along natural streams, negatively affecting biodiversity, but also providing timber and honey. When decision making is complex and uncertain, we suggest that rangeland managers utilize cost–benefit analyses and hold stakeholder workshops to resolve conflicts.

Studying the surface of Mercury with BepiColombo

NASA Astrophysics Data System (ADS)

Helbert, J.; Benkhoff, J.

2015-12-01

The payload of the ESA-JAXA mission BepiColombo had been proposed long before the NASA MESSENGER mission provided us with new insights into the innermost of the terrestrial planets. The discoveries of the MESSENGER fundamentally changed our view of Mercury. It revealed a surface that has been reshaped by volcanism over large parts of geological history. Volatile elements like sulfur have been detected with unexpectedly high abundances of up to 4%. MESSENGER imagined structures that are most likely formed by pyroclastic eruptions in recent geologic history. Among the most exciting discoveries of MESSENGER are hollows - bright irregularly shaped depressions that show sign of ongoing loss of material. BepiColombo will be building on what has been learned from the MESSENGER mission and extend the knowledge. Due to its more circular orbit BepiColombo will provide good spatial resolution for both hemispheres of Mercury. The mission will give us the first good look at the southern hemisphere of the planet. All spectral instruments are imaging and cover a wider spectral range than the instruments on MESSENGER. Some instruments will provide us datasets that have not been obtained by MESSENGER in any form. MERTIS will for example provide the first temperature map of Mercury and will map the surface composition of the planet for the first time in the thermal infrared. The telescopic imaging channel of the XRS instrument will provide elemental composition at an unprecedented spatial resolution. The MESSENGER results will be key to formulate the observation plan for the surface instruments on BepiColombo. They also have motivated a wide range of laboratory experiments that will help to better understand the results returned by the suite of instruments.

Recent advances of chitosan nanoparticles as drug carriers

PubMed Central

Wang, Jun Jie; Zeng, Zhao Wu; Xiao, Ren Zhong; Xie, Tian; Zhou, Guang Lin; Zhan, Xiao Ri; Wang, Shu Ling

2011-01-01

Chitosan nanoparticles are good drug carriers because of their good biocompatibility and biodegradability, and can be readily modified. As a new drug delivery system, they have attracted increasing attention for their wide applications in, for example, loading protein drugs, gene drugs, and anticancer chemical drugs, and via various routes of administration including oral, nasal, intravenous, and ocular. This paper reviews published research on chitosan nanoparticles, including its preparation methods, characteristics, modification, in vivo metabolic processes, and applications. PMID:21589644

JPRS Report, East Europe

DTIC Science & Technology

1990-09-28

depending on the kind of goods imported. As a result of the bilateral agreement a huge market has opened up for Hungary, a market , which at the same time...customs duty surcharge. There is a good chance that a very large, new market may be found as a result of the trade agreement, for example, for Hungarian... market ; the market does not exert its effects . But a constraint to make decisions has evolved, notably the fact that based on an earlier law enterprise

A detection method of vegetable oils in edible blended oil based on three-dimensional fluorescence spectroscopy technique.

PubMed

Xu, Jing; Liu, Xiao-Fei; Wang, Yu-Tian

2016-12-01

Edible blended vegetable oils are made from two or more refined oils. Blended oils can provide a wider range of essential fatty acids than single vegetable oils, which helps support good nutrition. Nutritional components in blended oils are related to the type and content of vegetable oils used, and a new, more accurate, method is proposed to identify and quantify the vegetable oils present using cluster analysis and a Quasi-Monte Carlo integral. Three-dimensional fluorescence spectra were obtained at 250-400nm (excitation) and 260-750nm (emission). Mixtures of sunflower, soybean and peanut oils were used as typical examples to validate the effectiveness of the method. Copyright © 2016 Elsevier Ltd. All rights reserved.

Good news on skylight performance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lewis, D.

1983-02-01

The effects of skylights on heating, cooling and lighting loads are examined using both winter and summer energy analysis. It is concluded that, in mild climates, skylights can save energy in summer and winter; in colder and cloudier climates, there may be a loss of energy in the winter but a savings in summer. The optimum skylight area is discussed for home and commercial applications. Glazing options (single, double, or triple), heat loss, air leakage, and condensation control are considered as well as ratio of glazing area to roof opening area, installation requirements, operation, and cleaning. An example skylight analysismore » is carried out for a Safeway supermarket in Tempe, Arizona. A list of skylight manufacturers and a source of additional information are provided. (MJJ)« less

Fast readout algorithm for cylindrical beam position monitors providing good accuracy for particle bunches with large offsets

NASA Astrophysics Data System (ADS)

Thieberger, P.; Gassner, D.; Hulsart, R.; Michnoff, R.; Miller, T.; Minty, M.; Sorrell, Z.; Bartnik, A.

2018-04-01

A simple, analytically correct algorithm is developed for calculating "pencil" relativistic beam coordinates using the signals from an ideal cylindrical particle beam position monitor (BPM) with four pickup electrodes (PUEs) of infinitesimal widths. The algorithm is then applied to simulations of realistic BPMs with finite width PUEs. Surprisingly small deviations are found. Simple empirically determined correction terms reduce the deviations even further. The algorithm is then tested with simulations for non-relativistic beams. As an example of the data acquisition speed advantage, a Field Programmable Gate Array-based BPM readout implementation of the new algorithm has been developed and characterized. Finally, the algorithm is tested with BPM data from the Cornell Preinjector.

Italian drug policy: ethical aims of essential assistance levels.

PubMed

Bernardi, Alessandra; Pegoraro, Renzo

2003-12-01

In 2001 the Italian Government defined Essential Assistance Levels (LEA), which can be considered as an important step forward in the health care system. The Italian health care system would provide payment of essential and uniform aid services in order to safeguard many values such as human dignity, personal health, equal assistance and good health practices. The Ministry of Health has worked to rationalize the National Formulary and to define evaluation methods for drugs in order to choose what to reimburse without penalizing the rights of the individual and society. This paper describes how this job of rationalization was done and tries to illustrate the choices made in Italy by the use of two meaningful examples (statins and rivastigmine).

Structural DNA Nanotechnology: From Design to Applications

PubMed Central

Zadegan, Reza M.; Norton, Michael L.

2012-01-01

The exploitation of DNA for the production of nanoscale architectures presents a young yet paradigm breaking approach, which addresses many of the barriers to the self-assembly of small molecules into highly-ordered nanostructures via construct addressability. There are two major methods to construct DNA nanostructures, and in the current review we will discuss the principles and some examples of applications of both the tile-based and DNA origami methods. The tile-based approach is an older method that provides a good tool to construct small and simple structures, usually with multiply repeated domains. In contrast, the origami method, at this time, would appear to be more appropriate for the construction of bigger, more sophisticated and exactly defined structures. PMID:22837684

Distribution of polarization-entangled photonpairs produced via spontaneous parametric down-conversion within a local-area fiber network: theoretical model and experiment.

PubMed

Lim, Han Chuen; Yoshizawa, Akio; Tsuchida, Hidemi; Kikuchi, Kazuro

2008-09-15

We present a theoretical model for the distribution of polarization-entangled photon-pairs produced via spontaneous parametric down-conversion within a local-area fiber network. This model allows an entanglement distributor who plays the role of a service provider to determine the photon-pair generation rate giving highest two-photon interference fringe visibility for any pair of users, when given user-specific parameters. Usefulness of this model is illustrated in an example and confirmed in an experiment, where polarization-entangled photon-pairs are distributed over 82 km and 132 km of dispersion-managed optical fiber. Experimentally observed visibilities and entanglement fidelities are in good agreement with theoretically predicted values.

Improved accuracy of solar energy system testing and measurements

NASA Astrophysics Data System (ADS)

Waterman, R. E.

1984-12-01

A real world example is provided of recovery of data on the performance of a solar collector system in the field. Kalman filters were devised to reconstruct data from sensors which had functioned only intermittently over the 3-day trial period designed to quantify phenomena in the collector loop, i.e., hot water delivered to storage. The filter was configured to account for errors in data on the heat exchanger coil differential temperature and mass flow rate. Data were then generated based on a matrix of state equations, taking into account the presence of time delays due to tank stratification and convective flows. Good correlations were obtained with data from other sensors for the flow rate, system temperatures and the energy delivered to storage.

Mean-field approximation for spacing distribution functions in classical systems.

PubMed

González, Diego Luis; Pimpinelli, Alberto; Einstein, T L

2012-01-01

We propose a mean-field method to calculate approximately the spacing distribution functions p((n))(s) in one-dimensional classical many-particle systems. We compare our method with two other commonly used methods, the independent interval approximation and the extended Wigner surmise. In our mean-field approach, p((n))(s) is calculated from a set of Langevin equations, which are decoupled by using a mean-field approximation. We find that in spite of its simplicity, the mean-field approximation provides good results in several systems. We offer many examples illustrating that the three previously mentioned methods give a reasonable description of the statistical behavior of the system. The physical interpretation of each method is also discussed. © 2012 American Physical Society

User's guide to PMESH: A grid-generation program for single-rotation and counterrotation advanced turboprops

NASA Technical Reports Server (NTRS)

Warsi, Saif A.

1989-01-01

A detailed operating manual is presented for a grid generating program that produces 3-D meshes for advanced turboprops. The code uses both algebraic and elliptic partial differential equation methods to generate single rotation and counterrotation, H or C type meshes for the z - r planes and H type for the z - theta planes. The code allows easy specification of geometrical constraints (such as blade angle, location of bounding surfaces, etc.), mesh control parameters (point distribution near blades and nacelle, number of grid points desired, etc.), and it has good runtime diagnostics. An overview is provided of the mesh generation procedure, sample input dataset with detailed explanation of all input, and example meshes.

250 kA compact linear transformer driver for wire array z-pinch loads

NASA Astrophysics Data System (ADS)

Bott, S. C.; Haas, D. M.; Madden, R. E.; Ueda, U.; Eshaq, Y.; Collins, G., IV; Gunasekera, K.; Mariscal, D.; Peebles, J.; Beg, F. N.; Mazarakis, M.; Struve, K.; Sharpe, R.

2011-05-01

We present the application of a short rise (˜150ns) 250 kA linear transformer driver (LTD) to wire array z-pinch loads for the first time. The generator is a modification of a previous driver in which a new conical power feed provides a low inductance coupling to wire loads. Performance of the new design using both short circuit and plasma loads is presented and discussed. The final design delivers ˜200kA to a wire array load which is in good agreement with SCREAMER calculations using a simplified representative circuit. Example results demonstrate successful experiments using cylindrical, conical, and inverse wire arrays as well as previously published work on x-pinch loads.

Fast readout algorithm for cylindrical beam position monitors providing good accuracy for particle bunches with large offsets

DOE PAGES

Thieberger, Peter; Gassner, D.; Hulsart, R.; ...

2018-04-25

Here, a simple, analytically correct algorithm is developed for calculating “pencil” relativistic beam coordinates using the signals from an ideal cylindrical particle beam position monitor (BPM) with four pickup electrodes (PUEs) of infinitesimal widths. The algorithm is then applied to simulations of realistic BPMs with finite width PUEs. Surprisingly small deviations are found. Simple empirically determined correction terms reduce the deviations even further. The algorithm is then tested with simulations for non-relativistic beams. As an example of the data acquisition speed advantage, a FPGA-based BPM readout implementation of the new algorithm has been developed and characterized. Lastly, the algorithm ismore » tested with BPM data from the Cornell Preinjector.« less

Fast readout algorithm for cylindrical beam position monitors providing good accuracy for particle bunches with large offsets

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thieberger, Peter; Gassner, D.; Hulsart, R.

Here, a simple, analytically correct algorithm is developed for calculating “pencil” relativistic beam coordinates using the signals from an ideal cylindrical particle beam position monitor (BPM) with four pickup electrodes (PUEs) of infinitesimal widths. The algorithm is then applied to simulations of realistic BPMs with finite width PUEs. Surprisingly small deviations are found. Simple empirically determined correction terms reduce the deviations even further. The algorithm is then tested with simulations for non-relativistic beams. As an example of the data acquisition speed advantage, a FPGA-based BPM readout implementation of the new algorithm has been developed and characterized. Lastly, the algorithm ismore » tested with BPM data from the Cornell Preinjector.« less

Positivity-preserving well-balanced discontinuous Galerkin methods for the shallow water flows in open channels

NASA Astrophysics Data System (ADS)

Qian, Shouguo; Li, Gang; Shao, Fengjing; Xing, Yulong

2018-05-01

We construct and study efficient high order discontinuous Galerkin methods for the shallow water flows in open channels with irregular geometry and a non-flat bottom topography in this paper. The proposed methods are well-balanced for the still water steady state solution, and can preserve the non-negativity of wet cross section numerically. The well-balanced property is obtained via a novel source term separation and discretization. A simple positivity-preserving limiter is employed to provide efficient and robust simulations near the wetting and drying fronts. Numerical examples are performed to verify the well-balanced property, the non-negativity of the wet cross section, and good performance for both continuous and discontinuous solutions.

[Clinical practice guidelines and knowledge management in healthcare].

PubMed

Ollenschläger, Günter

2013-10-01

Clinical practice guidelines are key tools for the translation of scientific evidence into everyday patient care. Therefore guidelines can act as cornerstones of evidence based knowledge management in healthcare, if they are trustworthy, and its recommendations are not biased by authors' conflict of interests. Good medical guidelines should be disseminated by means of virtual (digital/electronic) health libraries - together with implementation tools in context, such as guideline based algorithms, check lists, patient information, a.s.f. The article presents evidence based medical knowledge management using the German experiences as an example. It discusses future steps establishing evidence based health care by means of combining patient data, evidence from medical science and patient care routine, together with feedback systems for healthcare providers.

Adaptation of XMM-Newton SAS to GRID and VO architectures via web

NASA Astrophysics Data System (ADS)

Ibarra, A.; de La Calle, I.; Gabriel, C.; Salgado, J.; Osuna, P.

2008-10-01

The XMM-Newton Scientific Analysis Software (SAS) is a robust software that has allowed users to produce good scientific results since the beginning of the mission. This has been possible given the SAS capability to evolve with the advent of new technologies and adapt to the needs of the scientific community. The prototype of the Remote Interface for Science Analysis (RISA) presented here, is one such example, which provides remote analysis of XMM-Newton data with access to all the existing SAS functionality, while making use of GRID computing technology. This new technology has recently emerged within the astrophysical community to tackle the ever lasting problem of computer power for the reduction of large amounts of data.

Composite Dry Structure Cost Improvement Approach

NASA Technical Reports Server (NTRS)

Nettles, Alan; Nettles, Mindy

2015-01-01

This effort demonstrates that by focusing only on properties of relevance, composite interstage and shroud structures can be placed on the Space Launch System vehicle that simultaneously reduces cost, improves reliability, and maximizes performance, thus providing the Advanced Development Group with a new methodology of how to utilize composites to reduce weight for composite structures on launch vehicles. Interstage and shroud structures were chosen since both of these structures are simple in configuration and do not experience extreme environments (such as cryogenic or hot gas temperatures) and should represent a good starting point for flying composites on a 'man-rated' vehicle. They are used as an example only. The project involves using polymer matrix composites for launch vehicle structures, and the logic and rationale behind the proposed new methodology.

[How to write].

PubMed

Raos, Nenad

2002-09-01

In spite of a popular belief that every scientist knows how to write a professional paper, it is a sad fact that only a few scientists are really good writers. Hence the need for this paper. The process of writing is divided in three general steps (preparing, writing, and editing). In the first step, it is necessary to comprehend the future text as the whole. In the next step, one has to deal with its composition. In the third step, it is important to divide editing in precisely defined actions (adding and checking data, grammatical and stylistic corrections, spell-checking). The article also addresses certain differences between English and Croatian related to the meaning of words of Latin origin and provides examples of stylistic editing of scientific texts.

Quantitative aspects of inductively coupled plasma mass spectrometry

PubMed Central

Wagner, Barbara

2016-01-01

Accurate determination of elements in various kinds of samples is essential for many areas, including environmental science, medicine, as well as industry. Inductively coupled plasma mass spectrometry (ICP-MS) is a powerful tool enabling multi-elemental analysis of numerous matrices with high sensitivity and good precision. Various calibration approaches can be used to perform accurate quantitative measurements by ICP-MS. They include the use of pure standards, matrix-matched standards, or relevant certified reference materials, assuring traceability of the reported results. This review critically evaluates the advantages and limitations of different calibration approaches, which are used in quantitative analyses by ICP-MS. Examples of such analyses are provided. This article is part of the themed issue ‘Quantitative mass spectrometry’. PMID:27644971

Fast readout algorithm for cylindrical beam position monitors providing good accuracy for particle bunches with large offsets.

PubMed

Thieberger, P; Gassner, D; Hulsart, R; Michnoff, R; Miller, T; Minty, M; Sorrell, Z; Bartnik, A

2018-04-01

A simple, analytically correct algorithm is developed for calculating "pencil" relativistic beam coordinates using the signals from an ideal cylindrical particle beam position monitor (BPM) with four pickup electrodes (PUEs) of infinitesimal widths. The algorithm is then applied to simulations of realistic BPMs with finite width PUEs. Surprisingly small deviations are found. Simple empirically determined correction terms reduce the deviations even further. The algorithm is then tested with simulations for non-relativistic beams. As an example of the data acquisition speed advantage, a Field Programmable Gate Array-based BPM readout implementation of the new algorithm has been developed and characterized. Finally, the algorithm is tested with BPM data from the Cornell Preinjector.

29 CFR 779.349 - The 85-percent requirement.

Code of Federal Regulations, 2012 CFR

2012-07-01

.... 388.) Thus, for example, a bakery otherwise meeting the tests of 13(a)(4) making and selling baked... in the sale of baked goods to grocery stores for resale if such sales, together with other sales not...

29 CFR 779.349 - The 85-percent requirement.

Code of Federal Regulations, 2013 CFR

2013-07-01

.... 388.) Thus, for example, a bakery otherwise meeting the tests of 13(a)(4) making and selling baked... in the sale of baked goods to grocery stores for resale if such sales, together with other sales not...

29 CFR 779.349 - The 85-percent requirement.

Code of Federal Regulations, 2010 CFR

2010-07-01

.... 388.) Thus, for example, a bakery otherwise meeting the tests of 13(a)(4) making and selling baked... in the sale of baked goods to grocery stores for resale if such sales, together with other sales not...

29 CFR 779.349 - The 85-percent requirement.

Code of Federal Regulations, 2011 CFR

2011-07-01

.... 388.) Thus, for example, a bakery otherwise meeting the tests of 13(a)(4) making and selling baked... in the sale of baked goods to grocery stores for resale if such sales, together with other sales not...

29 CFR 779.349 - The 85-percent requirement.

Code of Federal Regulations, 2014 CFR

2014-07-01

.... 388.) Thus, for example, a bakery otherwise meeting the tests of 13(a)(4) making and selling baked... in the sale of baked goods to grocery stores for resale if such sales, together with other sales not...

Indoor Tanning

MedlinePlus

... proof that indoor tanning is safer than tanning outdoors. Indoor tanning systems give concentrated UV exposure regardless ... For example, it’s essential for promoting good bone health. While UV ... a tan to get that benefit. According to the Surgeon General, fair and light- ...

29 CFR 779.348 - Goods must be made at the establishment which sells them.

Code of Federal Regulations, 2011 CFR

2011-07-01

... not be exempt. The latter is a manufacturing establishment. For example, a candy kitchen manufacturing candy for sale at separate retail outlets is a manufacturing establishment and not a retail...

29 CFR 779.348 - Goods must be made at the establishment which sells them.

Code of Federal Regulations, 2010 CFR

2010-07-01

... not be exempt. The latter is a manufacturing establishment. For example, a candy kitchen manufacturing candy for sale at separate retail outlets is a manufacturing establishment and not a retail...

Helping Your Child Deal with Death

MedlinePlus

... a way to show that people will feel better. For example, "We all will go eat food together. People will laugh, talk, and hug some more. Focusing on the happy memories about Grandma and on the good feeling of ...

Nonlinear Road Pricing : [Summary

DOT National Transportation Integrated Search

2012-01-01

Nonlinear pricing is an unfamiliar term for a familiar idea. Linear pricing charges all consumers the same price for the same quantity of goods or services; in nonlinear schemes, the price varies, depending, for example, on quantity purchased or a co...

[Financing problems of capital goods: part 1: leasing as a solution?].

PubMed

Clausen, C C; Bauer, M; Saleh, A; Picker, O

2008-06-01

The provision of financial support of hospitals by States for buying capital goods is becoming increasingly more limited. In order to still make investments, alternative forms of financing such as leasing must be considered in hospitals. However, the change from the classical form of dual financing and the decision to opt for a leasing model involves much more than just a question of costs. Leasing results in easily manageable expenditure, flexibility and adaptability for the choice of model but the leasing installments must be directly financed by the turnover from diagnosis-related groups and so lead to a reduction in the annual profit. In this article the authors try to give the reader an overview of the complex and sometimes counter-productive effect of financial instruments for investments in hospitals using leasing financing as an example. In the follow-up article the decision-making procedure using dynamic investment calculations will be demonstrated using a concrete example.

Understanding Engineers' Responsibilities: A Prerequisite to Designing Engineering Education : Commentary on "Educating Engineers for the Public Good Through International Internships: Evidence from a Case Study at Universitat Politècnica de València".

PubMed

Murphy, Colleen; Gardoni, Paolo

2017-07-18

The development of the curriculum for engineering education (course requirements as well as extra-curricular activities like study abroad and internships) should be based on a comprehensive understanding of engineers' responsibilities. The responsibilities that are constitutive of being an engineer include striving to fulfill the standards of excellence set by technical codes; to improve the idealized models that engineers use to predict, for example, the behavior of alternative designs; and to achieve the internal goods such as safety and sustainability as they are reflected in the design codes. Globalization has implications for these responsibilities and, in turn, for engineering education, by, for example, modifying the collection of possible solutions recognized for existing problems. In addition, international internships can play an important role in fostering the requisite moral imagination of engineering students.

Calcium waves.

PubMed

Jaffe, Lionel F

2008-04-12

Waves through living systems are best characterized by their speeds at 20 degrees C. These speeds vary from those of calcium action potentials to those of ultraslow ones which move at 1-10 and/or 10-20 nm s(-1). All such waves are known or inferred to be calcium waves. The two classes of calcium waves which include ones with important morphogenetic effects are slow waves that move at 0.2-2 microm s(-1) and ultraslow ones. Both may be propagated by cycles in which the entry of calcium through the plasma membrane induces subsurface contraction. This contraction opens nearby stretch-sensitive calcium channels. Calcium entry through these channels propagates the calcium wave. Many slow waves are seen as waves of indentation. Some are considered to act via cellular peristalsis; for example, those which seem to drive the germ plasm to the vegetal pole of the Xenopus egg. Other good examples of morphogenetic slow waves are ones through fertilizing maize eggs, through developing barnacle eggs and through axolotl embryos during neural induction. Good examples of ultraslow morphogenetic waves are ones during inversion in developing Volvox embryos and across developing Drosophila eye discs. Morphogenetic waves may be best pursued by imaging their calcium with aequorins.

26 CFR 1.312-4 - Examples of adjustments provided in section 312(c).

Code of Federal Regulations, 2010 CFR

2010-04-01

... 26 Internal Revenue 4 2010-04-01 2010-04-01 false Examples of adjustments provided in section 312... (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Effects on Corporation § 1.312-4 Examples of adjustments... examples: Example 1. On December 2, 1954, Corporation X distributed to its sole shareholder, A, an...

Logical Fallacies and the Abuse of Climate Science: Fire, Water, and Ice

NASA Astrophysics Data System (ADS)

Gleick, P. H.

2012-12-01

Good policy without good science and analysis is unlikely. Good policy with bad science is even more unlikely. Unfortunately, there is a long history of abuse or misuse of science in fields with ideological, religious, or economically controversial policy implications, such as planetary physics during the time of Galileo, the evolution debate, or climate change. Common to these controversies are what are known as "logical fallacies" -- patterns of reasoning that are always -- or at least commonly -- wrong due to a flaw in the structure of the argument that renders the argument invalid. All scientists should understand the nature of logical fallacies in order to (1) avoid making mistakes and reaching unsupported conclusion, (2) help them understand and refute the flaws in arguments made by others, and (3) aid in communicating science to the public. This talk will present a series of logical fallacies often made in the climate science debate, including "arguments from ignorance," "arguments from error," "arguments from misinterpretation," and "cherry picking." Specific examples will be presented in the area of temperature analysis, water resources, and ice dynamics, with a focus on selective use or misuse of data.; "Argument from Error" - an amusing example of a logical fallacy.

Educating Emergency Managers About Weather -Related Hazards

NASA Astrophysics Data System (ADS)

Spangler, T. C.; Johnson, V.

2006-12-01

The most common crises that emergency managers face are those related to hazardous weather - snowstorms, floods, hurricanes, heat waves, tornadoes, etc. However, man-made disasters, such as accidental releases of hazardous substances or terrorist acts, also often have a weather component. For example, after the bombing of the Alfred P. Murrah Federal Building in Oklahoma City, emergency managers were concerned that thunderstorms in the area might cause the building to collapse, putting rescuers in further danger. Training emergency managers to recognize the importance of weather in disaster planning and response has been a small but important focus of the COMET Program's educational development effort. Topics addressed in COMET training modules that are pertinent to emergency management include fire weather, hurricanes, flood events, and air contaminant dispersion. Additionally, the module entitled Anticipating Hazardous Weather and Community Risk provides an overview of basic meteorological processes, describes a broad range of weather phenomenon, and then addresses what forecast products are available to emergency managers to assess a threat to their community. In many of the modules, learners are presented with scenarios that give them the opportunity to practice decision-making in hazardous weather situations. We will demonstrate some of those scenarios and discuss how training can be used to model good emergency management skills. We will discuss ways to communicate with the emergency management community and provide examples of how distance learning can be used to educate and train emergency managers.

Addressing the challenges of plasma-surface interactions in NSTX-U*

DOE PAGES

Kaita, Robert; Abrams, Tyler; Jaworski, Michael; ...

2015-04-01

The importance of conditioning plasma-facing components (PFCs) has long been recognized as a critical element in obtaining high-performance plasmas in magnetic confinement devices. Lithium coatings, for example, have been used for decades for conditioning PFCs. Since the initial studies on the Tokamak Fusion Test Reactor, experiments on devices with different aspect ratios and magnetic geometries like the National Spherical Torus Experiment (NSTX) continue to show the relationship between lithium PFCs and good confinement and stability. While such results are promising, their empirical nature do not reflect the detailed relationship between PFCs and the dynamic conditions that occur in the tokamakmore » environment. A first step developing an understanding such complexity will be taken in the upgrade to NSTX (NSTX-U) that is nearing completion. New measurement capabilities include the Materials Analysis and Particle Probe (MAPP) for in situ surface analysis of samples exposed to tokamak plasmas. The OEDGE suite of codes, for example, will provide a new way to model the underlying mechanisms for such material migration in NSTX-U. This will lead to a better understanding of how plasma-facing surfaces evolve during a shot, and how the composition of the plasma facing surface influences the discharge performance we observe. This paper will provide an overview of these capabilities, and highlight their importance for NSTX-U plans to transition from carbon to high-Z PFCs.« less

TargetMiner: microRNA target prediction with systematic identification of tissue-specific negative examples.

PubMed

Bandyopadhyay, Sanghamitra; Mitra, Ramkrishna

2009-10-15

Prediction of microRNA (miRNA) target mRNAs using machine learning approaches is an important area of research. However, most of the methods suffer from either high false positive or false negative rates. One reason for this is the marked deficiency of negative examples or miRNA non-target pairs. Systematic identification of non-target mRNAs is still not addressed properly, and therefore, current machine learning approaches are compelled to rely on artificially generated negative examples for training. In this article, we have identified approximately 300 tissue-specific negative examples using a novel approach that involves expression profiling of both miRNAs and mRNAs, miRNA-mRNA structural interactions and seed-site conservation. The newly generated negative examples are validated with pSILAC dataset, which elucidate the fact that the identified non-targets are indeed non-targets.These high-throughput tissue-specific negative examples and a set of experimentally verified positive examples are then used to build a system called TargetMiner, a support vector machine (SVM)-based classifier. In addition to assessing the prediction accuracy on cross-validation experiments, TargetMiner has been validated with a completely independent experimental test dataset. Our method outperforms 10 existing target prediction algorithms and provides a good balance between sensitivity and specificity that is not reflected in the existing methods. We achieve a significantly higher sensitivity and specificity of 69% and 67.8% based on a pool of 90 feature set and 76.5% and 66.1% using a set of 30 selected feature set on the completely independent test dataset. In order to establish the effectiveness of the systematically generated negative examples, the SVM is trained using a different set of negative data generated using the method in Yousef et al. A significantly higher false positive rate (70.6%) is observed when tested on the independent set, while all other factors are kept the same. Again, when an existing method (NBmiRTar) is executed with the our proposed negative data, we observe an improvement in its performance. These clearly establish the effectiveness of the proposed approach of selecting the negative examples systematically. TargetMiner is now available as an online tool at www.isical.ac.in/ approximately bioinfo_miu

Scaling ethics up and down: moral craft in clinical genetics and in global health research

PubMed Central

Parker, Michael

2015-01-01

This paper engages with the question of what it is to ‘do good medical ethics’ in two ways. It begins with an exploration of what it might mean to say that health professionals practise good medical ethics as part of practising good ethical medicine. Using the example of the Genethics Club, a well-established national ethics forum for genetics professionals in the UK, the paper develops an account of moral craftsmanship grounded in the concepts of shared moral commitments and practices, moral work, ethics and living morality. In the light of this discussion, the paper goes on to consider what it might mean for a specialist in medical ethics, a bioethicist, to do good medical ethics. Finally, a research agenda focusing on the challenges of thinking about good medical ethics in a global context and a proposal for an innovative approach to bioethics methodology is outlined. PMID:25516955

Pregnancy Constipation: Are Stool Softeners Safe?

MedlinePlus

... lifestyle changes. For example: Drink plenty of fluids. Water is a good choice. Prune juice also can help. Include physical activity in your daily routine. Being active can help prevent pregnancy constipation. Include more fiber in your diet. Choose high- ...

Ten Rules for Good Behavior.

ERIC Educational Resources Information Center

Hingsburger, Dave

1986-01-01

Ten guidelines for effective use of positive reinforcement as a parenting technique are described. Practical examples are used to illustrate such principles as consistency, immediacy, and specificity in giving praise. A distinction is made between giving reinforcement and giving love. (JW)

Utah Marbles and Mars Blueberries: Comparitive Terrestrial Analogs for Hematite Concretions on Mars

NASA Astrophysics Data System (ADS)

Chan, M. A.; Beitler, B.; Parry, W. T.; Ormö, J.; Komatsu, G.

2005-03-01

Compelling comparisons show why Utah iron oxide-cemented "marbles" are a good analog for Mars hematite "blueberries". Terrestrial examples offer valuable models for interpreting the diagenetic history and importance of water on Mars.

The Good Buy.

ERIC Educational Resources Information Center

Newsom, John

2002-01-01

Describes school purchasing process, examples of illegal or wasteful purchasing activities, a concise ethical guide to school purchasing excerpted from the Texas Agency's Financial Accountability System Resource Guide, and suggestions from experts on how schools can ensure legal and ethical purchasing practices. (PKP)

STDs and ecological niches (image)

MedlinePlus

Many sexually-transmitted diseases (STDs) invade the host and reside for long periods of time without killing the host. A good example is syphilis, which may reside in its host for 30 to 50 years. HIV also can take 10 or ...

Our Culture/Your Good Intentions (Reflections).

ERIC Educational Resources Information Center

Hewett, Kerri-Ann

1996-01-01

Offers a Native Hawaiian educator's perspective on the well- intentioned but misguided efforts of many non-Native teachers, administrators, and professors. Uses the Kamehameha Early Education Program as an example of an authoritarian discourse being taught to Native children. (SR)

Blackhole formula and example relativity

NASA Astrophysics Data System (ADS)

Shin, Philip

Black hole formula 1) Second dimension (x,y) f(x)=y Energy E=m*c2 2) Third dimension (x,y,z) really x=y=z Black hole formula Root(c2)=c=Root(E/m) As mass go the velocity of light, mass become black hole so there are energy as multiply by mass. Example relativity When E=m*c2 1) Root(c2)=c=Root(E/m) 2) 3*c*Root(c2)=3*c*Root(E/m)=3*c2 From 1) to 2) as an example, As velocity is faster, mass increased. It means when velocity is increased, sec(time) is slower, and m(distance) is increased. The number is good to study physics.

Phenomenology in nursing research: methodology, interviewing and transcribing.

PubMed

Balls, Paula

While nurses can relate to the phenomenological approach because they see it as sharing the values of nursing, this may not be sufficient on its own to start conducting this kind of research. Using examples from my own research experience, this article aims to examine what draws nursing to this method and why nurses think they may be good at it. It also offers practical advice on how to carry out a good interview, how and what to transcribe and how to use quotes to support research.

[The treatment of patients with traumatic osteomyelitis of the mandible by using porous permeable titanium nickelide implants].

PubMed

Tazin, I D; Sysoliatin, P G; Panov, L A; Giunter, V E

2000-01-01

Use of titanium nickelide based porous permeable implants for repair of postosteomyelitis mandibular defects is discussed. Five patients with mandibular defects of different location and extent were operated on. Surgical methods are described. A clinical example of using a porous permeable implant is offered. The implant designed as a mandible was used for repair of an extensive mandibular defect. Good immediate and remote results of operations indicate good prospects of using such implants.

Machiavelli and the chief resident.

PubMed

Raviglione, M C

1990-06-01

A good chief resident is under pressure from residents and the department director and must work for the welfare of both the housestaff and the institution. Using precepts from Niccoló Machiavelli's The Prince, the author gives advice for chief residents on how to balance their responsibilities. The author, using Machiavelli's precepts, discusses the difficulties of introducing change, supervising former colleagues and peers, the opprobrium that inevitably attaches to tough decisions, the need to set good examples, and other aspects of being a chief resident.

Defense AT&L (Volume 36, Number 2, March-April 2007)

DTIC Science & Technology

2007-04-01

87 28 The Pursuit of Courage, Judg- ment, and Luck Maj. Dan Ward, USAF Maj. Chris Quaid, USAF Conventional wisdom states that a closed risk is a good...example) that could be as much as 50 percent dirt. Many agencies were buying adobe bricks that were not kiln -fired, so within two or three seasons of...all too many PMs think a good risk management process simply identifies and mitigates the bad things that can happen. Conventional risk manage- ment

New Material Development for Surface Layer and Surface Technology in Tribology Science to Improve Energy Efficiency

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ismail, R., E-mail: rifky-mec@yahoo.com; Tauviqirrahman, M., E-mail: rifky-mec@yahoo.com; Laboratory for Surface Technology and Tribology, Faculty of Engineering Technology, University of Twente, Enschede

This paper reviews the development of new material and surface technology in tribology and its contribution to energy efficiency. Two examples of the economic benefits, resulted from the optimum tribology in the transportation sector and the manufacturing industry are discussed. The new materials are proposed to modify the surface property by laminating the bulk material with thin layer/coating. Under a suitable condition, the thin layer on a surface can provide a combination of good wear, a low friction and corrosion resistance for the mechanical components. The innovation in layer technology results molybdenum disulfide (MoS2), diamond like carbon (DLC), cubic boronmore » nitride (CBN) and diamond which perform satisfactory outcome. The application of the metallic coatings to carbon fibre reinforced polymer matrix composites (CFRP) has the capacity to provide considerable weight and power savings for many engineering components. The green material for lubricant and additives such as the use of sunflower oil which possesses good oxidation resistance and the use of mallee leaves as bio‐degradable solvent are used to answer the demand of the environmentally friendly material with good performance. The tribology research implementation for energy efficiency also touches the simple things around us such as: erasing the laser‐print in a paper with different abrasion techniques. For the technology in the engineering surface, the consideration for generating the suitable surface of the components in running‐in period has been discussed in order to prolong the components life and reduce the machine downtime. The conclusion, tribology can result in reducing manufacturing time, reducing the maintenance requirements, prolonging the service interval, improving durability, reliability and mechanical components life, and reducing harmful exhaust emission and waste. All of these advantages will increase the energy efficiency and the economic benefits.« less

New Material Development for Surface Layer and Surface Technology in Tribology Science to Improve Energy Efficiency

NASA Astrophysics Data System (ADS)

Ismail, R.; Tauviqirrahman, M.; Jamari, Jamari; Schipper, D. J.

2009-09-01

This paper reviews the development of new material and surface technology in tribology and its contribution to energy efficiency. Two examples of the economic benefits, resulted from the optimum tribology in the transportation sector and the manufacturing industry are discussed. The new materials are proposed to modify the surface property by laminating the bulk material with thin layer/coating. Under a suitable condition, the thin layer on a surface can provide a combination of good wear, a low friction and corrosion resistance for the mechanical components. The innovation in layer technology results molybdenum disulfide (MoS2), diamond like carbon (DLC), cubic boron nitride (CBN) and diamond which perform satisfactory outcome. The application of the metallic coatings to carbon fibre reinforced polymer matrix composites (CFRP) has the capacity to provide considerable weight and power savings for many engineering components. The green material for lubricant and additives such as the use of sunflower oil which possesses good oxidation resistance and the use of mallee leaves as bio-degradable solvent are used to answer the demand of the environmentally friendly material with good performance. The tribology research implementation for energy efficiency also touches the simple things around us such as: erasing the laser-print in a paper with different abrasion techniques. For the technology in the engineering surface, the consideration for generating the suitable surface of the components in running-in period has been discussed in order to prolong the components life and reduce the machine downtime. The conclusion, tribology can result in reducing manufacturing time, reducing the maintenance requirements, prolonging the service interval, improving durability, reliability and mechanical components life, and reducing harmful exhaust emission and waste. All of these advantages will increase the energy efficiency and the economic benefits.

A Total Economic Valuation of Wetland Ecosystem Services: An Evidence from Jagadishpur Ramsar Site, Nepal

PubMed Central

Basnyat, Bijendra; Khanal, Rajendra; Gauli, Kalyan

2016-01-01

Wetlands are the most productive ecosystem and provide wide arrays of wetland ecosystems (goods and services) to the local communities in particular and global communities in general. However, management of the wetland often does not remain priority and recognized as the unproductive waste land mainly due to poor realization of the economic value of the wetlands. Taking this into account, the study estimated the total economic value of the Jagadishpur Reservoir taking into account direct, indirect, and nonuse value. The study prioritized six major values of the reservoir which include wetland goods consumption, tourism, irrigation, carbon sequestration, biodiversity conservation, and conservation for future use (existence and option value). The study used market and nonmarket based valuation techniques to estimate total economic value of the reservoir. Household survey, focus group discussions, and interaction with the tourism entrepreneurs and district stakeholders were carried out to collect information. The study estimated the total annual economic value of the reservoir as NRs 94.5 million, where option/existence value remains main contributor followed by direct use value such as wetland goods and tourism and indirect use value, for example, carbon sequestration, biodiversity conservation, and irrigation. The study reveals that the local communities gave high importance to the future use value and are willing to make investment for conservation and restoration of reservoir given its conservation significance. PMID:27830175

A Total Economic Valuation of Wetland Ecosystem Services: An Evidence from Jagadishpur Ramsar Site, Nepal.

PubMed

Baral, Sony; Basnyat, Bijendra; Khanal, Rajendra; Gauli, Kalyan

Wetlands are the most productive ecosystem and provide wide arrays of wetland ecosystems (goods and services) to the local communities in particular and global communities in general. However, management of the wetland often does not remain priority and recognized as the unproductive waste land mainly due to poor realization of the economic value of the wetlands. Taking this into account, the study estimated the total economic value of the Jagadishpur Reservoir taking into account direct, indirect, and nonuse value. The study prioritized six major values of the reservoir which include wetland goods consumption, tourism, irrigation, carbon sequestration, biodiversity conservation, and conservation for future use (existence and option value). The study used market and nonmarket based valuation techniques to estimate total economic value of the reservoir. Household survey, focus group discussions, and interaction with the tourism entrepreneurs and district stakeholders were carried out to collect information. The study estimated the total annual economic value of the reservoir as NRs 94.5 million, where option/existence value remains main contributor followed by direct use value such as wetland goods and tourism and indirect use value, for example, carbon sequestration, biodiversity conservation, and irrigation. The study reveals that the local communities gave high importance to the future use value and are willing to make investment for conservation and restoration of reservoir given its conservation significance.

Determination of lamb wave dispersion data in lossy anisotropic plates using time domain finite element analysis. Part I: theory and experimental verification.

PubMed

Hayward, Gordon; Hyslop, Jamie

2006-02-01

A theoretical and experimental approach for extraction of guided wave dispersion data in plate structures is described. Finite element modeling is used to calculate the surface displacement data (in-plane and out-of-plane) when the plate is subject to either symmetrical or antisymmetrical impulsive force stimulation at one or both of the parallel faces. Fourier transformation of the resultant space-time displacement histories is then employed to obtain phase velocity as a function of frequency. Experimental verification in the case of antisymmetrical stimulation is provided by means of a high-power Q-switched laser source that is used to excite guided waves in the plate. The subsequent out-of-plane displacement data were then obtained by means of a scanning laser vibrometer, and good agreement between theory and experiment is demonstrated. Examples of dispersion data are provided for aluminum, and excellent correlation between the data sets and conventional Rayleigh-Lamb theory for plate structures was obtained. This was then extended to lossy polymeric plates, in addition to both unpolarized and polarized piezoelectric ceramic plates, again with good agreement between the finite element modeling and optical experiments. The last set of results prepares the way for a detailed investigation of the nonhomogeneous piezoelectric composite waveguides described in a companion paper (Part II).

Inclusion of disability within national strategic responses to HIV and AIDS in Eastern and Southern Africa.

PubMed

Hanass-Hancock, Jill; Strode, Ann; Grant, Catherine

2011-01-01

National strategic plans (NSPs) provide a framework for a comprehensive response to human immunodeficiency virus (HIV) including strategies such as prevention, treatment, care and support for all affected. Research indicates limited recognition of the interrelationship between disability and HIV in the Eastern and Southern Africa (ESA). This paper analyses the extent to which NSPs in ESA address disability, and identify good practice. Using a tool based on relevant rights in the UN Convention on the Rights of Persons with Disabilities and the UNAIDS International Guidelines on HIV and Human Rights, a review of 18 NSPs in ESA was conducted to determine the extent to which they included disability. Although many NSPs fail to integrate disability issues, there are examples of good practice from which much can be learned, particularly with respect to disability and HIV-prevention efforts. There is limited provision for treatment, care and support for disability in the context of HIV and AIDS. Many NSPs in ESA are due for review, providing ample opportunities for the development of disability-inclusive responses. Future NSPs need to integrate the needs of people with disabilities within structures, programmes and monitoring and evaluation, and make provision for increased rehabilitation needs caused by HIV. A rights-based approach and specific financial allocation of resources are crucial for this process.

Improved triage and emergency care for children reduces inpatient mortality in a resource-constrained setting.

PubMed Central

Molyneux, Elizabeth; Ahmad, Shafique; Robertson, Ann

2006-01-01

PROBLEM: Early assessment, prioritization for treatment and management of sick children attending a health service are critical to achieving good outcomes. Many hospitals in developing countries see large numbers of patients and have few staff, so patients often have to wait before being assessed and treated. APPROACH: We present the example of a busy Under-Fives Clinic that provided outpatient services, immunizations and treatment for medical emergencies. The clinic was providing an inadequate service resulting in some inappropriate admissions and a high case-fatality rate. We assessed the deficiencies and sought resources to improve services. LOCAL SETTING: A busy paediatric outpatient clinic in a public tertiary care hospital in Blantyre, Malawi. RELEVANT CHANGES: The main changes we made were to train staff in emergency care and triage, improve patient flow through the department and to develop close cooperation between inpatient and outpatient services. Training coincided with a restructuring of the physical layout of the department. The changes were put in place when the department reopened in January 2001. LESSONS LEARNED: Improvements in the process and delivery of care and the ability to prioritize clinical management are essential to good practice. Making the changes described above has streamlined the delivery of care and led to a reduction in inpatient mortality from 10-18% before the changes were made (before 2001) to 6-8% after. PMID:16628305

Possibilities of LA-ICP-MS technique for the spatial elemental analysis of the recent fish scales: Line scan vs. depth profiling

NASA Astrophysics Data System (ADS)

Holá, Markéta; Kalvoda, Jiří; Nováková, Hana; Škoda, Radek; Kanický, Viktor

2011-01-01

LA-ICP-MS and solution based ICP-MS in combination with electron microprobe are presented as a method for the determination of the elemental spatial distribution in fish scales which represent an example of a heterogeneous layered bone structure. Two different LA-ICP-MS techniques were tested on recent common carp ( Cyprinus carpio) scales: A line scan through the whole fish scale perpendicular to the growth rings. The ablation crater of 55 μm width and 50 μm depth allowed analysis of the elemental distribution in the external layer. Suitable ablation conditions providing a deeper ablation crater gave average values from the external HAP layer and the collagen basal plate. Depth profiling using spot analysis was tested in fish scales for the first time. Spot analysis allows information to be obtained about the depth profile of the elements at the selected position on the sample. The combination of all mentioned laser ablation techniques provides complete information about the elemental distribution in the fish scale samples. The results were compared with the solution based ICP-MS and EMP analyses. The fact that the results of depth profiling are in a good agreement both with EMP and PIXE results and, with the assumed ways of incorporation of the studied elements in the HAP structure, suggests a very good potential for this method.

Evolution and Operations of the Reston Virginia Commuter Bus Service

DOT National Transportation Integrated Search

1977-08-01

The report focuses on documenting and assessing the evolution and operations of the Reston Commuter Bus (RCB). RCB is a good example of a community group overcoming many legal, regulatory, and institutional constraints to develop and refine a viable ...