Improved Pulse Transit Time Estimation by System Identification Analysis of Proximal and Distal Arterial Waveforms

DTIC Science & Technology

2011-10-01

response; pulse wave velocity ACCORDING TO THE MOENS-KORTEWEG equation, pulse wave ve- locity ( PWV ) increases as the arteries stiffen. Indeed, PWV is the...and mortality in hypertensive patients (2, 4, 12, 14). In addition, because arterial stiffness increases with arterial blood pressure (ABP), PWV and...ABP often show positive correlation, suggesting that PWV could provide a means to achieve continuous, noninvasive, and cuffless ABP monitoring (18

Frequency modulation and compression of optical pulses in an optical fibre with a travelling refractive-index wave

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zolotovskii, I O; Lapin, V A; Sementsov, D I

2016-01-31

We have studied the conditions for spectral broadening, frequency modulation and compression (both temporal and spectral) of Gaussian pulses propagating in a fibre with a travelling refractive-index wave. Analytical expressions have been derived for the dependences of pulse duration, chirp and spectral width on the distance travelled through the fibre, parameters of the fibre and radiation launched into it. Based on the numerical analysis we have studied the behaviour of these characteristics by changing the coefficient of the refractive-index modulation and other parameters of the travelling refractive-index wave. (nonlinear optical phenomena)

Insulin-resistance HCV infection-related affects vascular stiffness in normotensives.

PubMed

Perticone, Maria; Maio, Raffaele; Tassone, Eliezer Joseph; Tripepi, Giovanni; Di Cello, Serena; Miceli, Sofia; Caroleo, Benedetto; Sciacqua, Angela; Licata, Anna; Sesti, Giorgio; Perticone, Francesco

2015-01-01

BACKGROUND AND AIMS. Arterial stiffness evaluated as pulse wave velocity, is an early marker of vascular damage and an independent predictor for cardiovascular events. We investigated if the insulin resistance/hyperinsulinemia chronic hepatitis C virus infection-related could influence arterial stiffness. METHODS. We enrolled 260 outpatients matched for age, body mass index, gender, ethnicity: 52 with never-treated uncomplicated chronic hepatitis C virus infection (HCV(+)), 104 never-treated hypertensives (HT) and 104 healthy subjects (NT). Pulse wave velocity was evaluated by a validated system employing high-fidelity applanation tonometry. We also measured: fasting plasma glucose and insulin, total, LDL- and HDL-cholesterol, triglyceride, creatinine, e-GFR-EPI, HOMA, quantitative HCV-RNA. RESULTS. HCV(+) patients with respect to NT had an increased pulse wave velocity (7.9 ± 2.1 vs 6.4 ± 2.1 m/s; P < 0.0001), similar to that observed in HT group (8.8 ± 3.2 m/s). HCV(+) patients, in comparison with NT, had higher triglyceride, creatinine, fasting insulin and HOMA (3.2 ± 1.3 vs 2.5 ± 1.0; P < 0.0001). At linear regression analysis, the correlation between pulse wave velocity and HOMA was similar in HT (r = 0.380, P < 0.0001) and HCV(+) (r = 0.369, P = 0.004) groups. At multiple regression analysis, HOMA resulted the major determinant of pulse wave velocity in all groups, explaining respectively 11.8%, 14.4% and 13.6% of its variation in NT, HT and HCV(+). At correlational analysis hepatitis C virus-RNA and HOMA demonstrated a strong and linear relationship between them, explaining the 72.4% of their variation (P = 0.022). CONCLUSIONS. We demonstrated a significant and direct correlation between HOMA and pulse wave velocity in HCV(+) patients, similar to that observed in hypertensives. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Chirped self-similar optical pulses in tapered centrosymmetric nonlinear waveguides doped with resonant impurities

NASA Astrophysics Data System (ADS)

He, J. R.; Xu, S. L.; Xue, L.

2017-11-01

Exact chirped self-similar optical pulses propagating in tapered centrosymmetric nonlinear waveguides doped with resonant impurities are reported. The propagation behaviors of the pulses are studied by tailoring of the tapering function. Numerical simulations and stability analysis reveal that the tapering can be used to postpone the wave dispersion and the addition of a small cubic self-focusing term to the governing equation could stabilize the chirped bright pulses. An example of possible experimental protocol that may generate the pulses in realistic waveguides is given. The obtained chirped self-similar optical pulses are particularly useful in the design of amplifying or attenuating pulse compressors for chirped solitary waves in tapered centrosymmetric nonlinear waveguides doped with resonant impurities.

Gastric electrical stimulation with short pulses reduces vomiting but not dysrhythmias in dogs.

PubMed

Chen, Jiande D Z; Qian, Liwei; Ouyang, Hui; Yin, Jieyun

2003-02-01

The aim of this study was to investigate the acute effects of 3 different methods of electrical stimulation in the prevention of vasopressin-induced emetic response and gastric dysrhythmias. Seven female hound dogs chronically implanted with 4 pairs of electrodes on gastric serosa were used in a 5-session study. Saline and vasopressin were infused in sessions 1 and 2, respectively. In the other 3 sessions with vasopressin infusion, 3 different methods of electrical stimulation (short-pulse stimulation, long-pulse stimulation, and electroacupuncture) were applied. Gastric slow waves and vomiting and behaviors suggestive of nausea were recorded in each session. In a separate study, additional experiments were performed in 5 vagotomized dogs to investigate vagally mediated mechanisms. Vasopressin induced gastric dysrhythmias, uncoupling of slow waves, and vomiting and behaviors suggestive of nausea (P < 0.02, analysis of variance). Long-pulse stimulation, but not short-pulse stimulation or electroacupuncture, was capable of preventing vasopressin-induced gastric dysrhythmias and gastric slow wave uncoupling. Short-pulse stimulation and electroacupuncture, but not long-pulse stimulation, prevented vomiting and significantly reduced the symptom scores, which was not noted in the dogs with truncal vagotomy. Long-pulse stimulation normalizes vasopressin-induced slow wave abnormalities with no improvement in vomiting and behaviors suggestive of nausea. Short-pulse stimulation and electroacupuncture prevent vomiting and behaviors suggestive of nausea induced by vasopressin but have no effects on slow waves, and their effects are vagally mediated.

High resolution wavenumber analysis for investigation of arterial pulse wave propagation

NASA Astrophysics Data System (ADS)

Hasegawa, Hideyuki; Sato, Masakazu; Irie, Takasuke

2016-07-01

The propagation of the pulse wave along the artery is relatively fast (several m/s), and a high-temporal resolution is required to measure pulse wave velocity (PWV) in a regional segment of the artery. High-frame-rate ultrasound enables the measurement of the regional PWV. In analyses of wave propagation phenomena, the direction and propagation speed are generally identified in the frequency-wavenumber space using the two-dimensional Fourier transform. However, the wavelength of the pulse wave is very long (1 m at a propagation velocity of 10 m/s and a temporal frequency of 10 Hz) compared with a typical lateral field of view of 40 mm in ultrasound imaging. Therefore, PWV cannot be identified in the frequency-wavenumber space owing to the low resolution of the two-dimensional Fourier transform. In the present study, PWV was visualized in the wavenumber domain using phases of arterial wall acceleration waveforms measured by high-frame-rate ultrasound.

Comparative study of methodologies for pulse wave velocity estimation.

PubMed

Salvi, P; Magnani, E; Valbusa, F; Agnoletti, D; Alecu, C; Joly, L; Benetos, A

2008-10-01

Arterial stiffness, estimated by pulse wave velocity (PWV), is an independent predictor of cardiovascular mortality and morbidity. However, the clinical applicability of these measurements and the elaboration of reference PWV values are difficult due to differences between the various devices used. In a population of 50 subjects aged 20-84 years, we compared PWV measurements with three frequently used devices: the Complior and the PulsePen, both of which determine aortic PWV as the delay between carotid and femoral pressure wave and the PulseTrace, which estimates the Stiffness Index (SI) by analyzing photoplethysmographic waves acquired on the fingertip. PWV was measured twice by each device. Coefficient of variation of PWV was 12.3, 12.4 and 14.5% for PulsePen, Complior and PulseTrace, respectively. These measurements were compared with the reference method, that is, a simultaneous acquisition of pressure waves using two tonometers. High correlation coefficients with the reference method were observed for PulsePen (r = 0.99) and Complior (r = 0.83), whereas for PulseTrace correlation with the reference method was much lower (r = 0.55). Upon Bland-Altman analysis, mean differences of values +/- 2s.d. versus the reference method were -0.15 +/- 0.62 m/s, 2.09 +/- 2.68 m/s and -1.12 +/- 4.92 m/s, for PulsePen, Complior and Pulse-Trace, respectively. This study confirms the reliability of Complior and PulsePen devices in estimating PWV, while the SI determined by the PulseTrace device was found to be inappropriate as a surrogate of PWV. The present results indicate the urgent need for evaluation and comparison of the different devices to standardize PWV measurements and establish reference values.

Aortic stiffness is associated with visceral adiposity in older adults enrolled in the study of health, aging, and body composition.

PubMed

Sutton-Tyrrell, K; Newman, A; Simonsick, E M; Havlik, R; Pahor, M; Lakatta, E; Spurgeon, H; Vaitkevicius, P

2001-09-01

The central arteries stiffen with age, causing hemodynamic alterations that have been associated with cardiovascular events. Changes in body fat with age may be related to aortic stiffening. The association between vascular stiffness and body fat was evaluated in 2488 older adults (mean age, 74 years; 52% female; 40% black) enrolled in the Study of Health, Aging, and Body Composition (Health ABC), a prospective study of changes in weight and body composition. Clinical sites were located in Pittsburgh, Pa, and Memphis, Tenn. Aortic pulse wave velocity was used as an indirect measure of aortic stiffness. A faster pulse wave velocity indicates a stiffer aorta. Body fat measures were evaluated with dual energy x-ray absorptiometry and computed tomography. Independent of age and blood pressure, pulse wave velocity was positively associated with weight, abdominal circumference, abdominal subcutaneous fat, abdominal visceral fat, thigh fat area, and total fat (P<0.001 for all). The strongest association was with abdominal visceral fat. Elevated pulse wave velocity was also positively associated with history of diabetes and higher levels of glucose, insulin, and hemoglobin A1c (P<0.001 for all). In multivariate analysis, independent positive associations with pulse wave velocity were found for age, systolic blood pressure, heart rate, abdominal visceral fat, smoking, hemoglobin A1c, and history of hypertension. The association between pulse wave velocity and abdominal visceral fat was consistent across tertiles of body weight. Among older adults, higher levels of visceral fat are associated with greater aortic stiffness as measured by pulse wave velocity.

Multi-Gaussian fitting for pulse waveform using Weighted Least Squares and multi-criteria decision making method.

PubMed

Wang, Lu; Xu, Lisheng; Feng, Shuting; Meng, Max Q-H; Wang, Kuanquan

2013-11-01

Analysis of pulse waveform is a low cost, non-invasive method for obtaining vital information related to the conditions of the cardiovascular system. In recent years, different Pulse Decomposition Analysis (PDA) methods have been applied to disclose the pathological mechanisms of the pulse waveform. All these methods decompose single-period pulse waveform into a constant number (such as 3, 4 or 5) of individual waves. Furthermore, those methods do not pay much attention to the estimation error of the key points in the pulse waveform. The estimation of human vascular conditions depends on the key points' positions of pulse wave. In this paper, we propose a Multi-Gaussian (MG) model to fit real pulse waveforms using an adaptive number (4 or 5 in our study) of Gaussian waves. The unknown parameters in the MG model are estimated by the Weighted Least Squares (WLS) method and the optimized weight values corresponding to different sampling points are selected by using the Multi-Criteria Decision Making (MCDM) method. Performance of the MG model and the WLS method has been evaluated by fitting 150 real pulse waveforms of five different types. The resulting Normalized Root Mean Square Error (NRMSE) was less than 2.0% and the estimation accuracy for the key points was satisfactory, demonstrating that our proposed method is effective in compressing, synthesizing and analyzing pulse waveforms. Copyright © 2013 Elsevier Ltd. All rights reserved.

In vivo analysis of THz wave irradiation induced acute inflammatory response in skin by laser-scanning confocal microscopy.

PubMed

Hwang, Yoonha; Ahn, Jinhyo; Mun, Jungho; Bae, Sangyoon; Jeong, Young Uk; Vinokurov, Nikolay A; Kim, Pilhan

2014-05-19

The recent development of THz sources in a wide range of THz frequencies and power levels has led to greatly increased interest in potential biomedical applications such as cancer and burn wound diagnosis. However, despite its importance in realizing THz wave based applications, our knowledge of how THz wave irradiation can affect a live tissue at the cellular level is very limited. In this study, an acute inflammatory response caused by pulsed THz wave irradiation on the skin of a live mouse was analyzed at the cellular level using intravital laser-scanning confocal microscopy. Pulsed THz wave (2.7 THz, 4 μs pulsewidth, 61.4 μJ per pulse, 3Hz repetition), generated using compact FEL, was used to irradiate an anesthetized mouse's ear skin with an average power of 260 mW/cm(2) for 30 minutes using a high-precision focused THz wave irradiation setup. In contrast to in vitro analysis using cultured cells at similar power levels of CW THz wave irradiation, no temperature change at the surface of the ear skin was observed when skin was examined with an IR camera. To monitor any potential inflammatory response, resident neutrophils in the same area of ear skin were repeatedly visualized before and after THz wave irradiation using a custom-built laser-scanning confocal microscopy system optimized for in vivo visualization. While non-irradiated control skin area showed no changes in the number of resident neutrophils, a massive recruitment of newly infiltrated neutrophils was observed in the THz wave irradiated skin area after 6 hours, which suggests an induction of acute inflammatory response by the pulsed THz wave irradiation on the skin via a non-thermal process.

Measurement of energy contrast of amplified ultrashort pulses using cross-polarized wave generation and spectral interferometry.

PubMed

Iliev, Marin; Meier, Amanda K; Galloway, Benjamin; Adams, Daniel E; Squier, Jeff A; Durfee, Charles G

2014-07-28

We present a method using spectral interferometry (SI) to characterize a pulse in the presence of an incoherent background such as amplified spontaneous emission (ASE). The output of a regenerative amplifier is interfered with a copy of the pulse that has been converted using third-order cross-polarized wave generation (XPW). The ASE shows as a pedestal background in the interference pattern. The energy contrast between the short-pulse component and the ASE is retrieved. The spectra of the interacting beams are obtained through an improvement to the self-referenced spectral interferometry (SRSI) analysis.

Non-contact measurement of pulse wave velocity using RGB cameras

NASA Astrophysics Data System (ADS)

Nakano, Kazuya; Aoki, Yuta; Satoh, Ryota; Hoshi, Akira; Suzuki, Hiroyuki; Nishidate, Izumi

2016-03-01

Non-contact measurement of pulse wave velocity (PWV) using red, green, and blue (RGB) digital color images is proposed. Generally, PWV is used as the index of arteriosclerosis. In our method, changes in blood volume are calculated based on changes in the color information, and is estimated by combining multiple regression analysis (MRA) with a Monte Carlo simulation (MCS) model of the transit of light in human skin. After two pulse waves of human skins were measured using RGB cameras, and the PWV was calculated from the difference of the pulse transit time and the distance between two measurement points. The measured forehead-finger PWV (ffPWV) was on the order of m/s and became faster as the values of vital signs raised. These results demonstrated the feasibility of this method.

Aortic stiffness predicts functional outcome in patients after ischemic stroke.

PubMed

Gasecki, Dariusz; Rojek, Agnieszka; Kwarciany, Mariusz; Kubach, Marlena; Boutouyrie, Pierre; Nyka, Walenty; Laurent, Stephane; Narkiewicz, Krzysztof

2012-02-01

Increased aortic stiffness (measured by carotid-femoral pulse wave velocity) and central augmentation index have been shown to independently predict cardiovascular events, including stroke. We studied whether pulse wave velocity and central augmentation index predict functional outcome after ischemic stroke. In a prospective study, we enrolled 99 patients with acute ischemic stroke (age 63.7 ± 12.4 years, admission National Institutes of Health Stroke Scale score 6.6 ± 6.6, mean ± SD). Carotid-femoral pulse wave velocity and central augmentation index (SphygmoCor) were measured 1 week after stroke onset. Functional outcome was evaluated 90 days after stroke using the modified Rankin Scale with modified Rankin Scale score of 0 to 1 considered an excellent outcome. In univariate analysis, low carotid-femoral pulse wave velocity (P=0.000001) and low central augmentation index (P=0.028) were significantly associated with excellent stroke outcome. Age, severity of stroke, presence of previous stroke, diabetes, heart rate, and peripheral pressures also predicted stroke functional outcome. In multivariate analysis, the predictive value of carotid-femoral pulse wave velocity (<9.4 m/s) remained significant (OR, 0.21; 95% CI, 0.06-0.79; P=0.02) after adjustment for age, National Institutes of Health Stroke Scale score on admission, and presence of previous stroke. By contrast, central augmentation index had no significant predictive value after adjustment. This study indicates that aortic stiffness is an independent predictor of functional outcome in patients with acute ischemic stroke.

An analysis of short pulse and dual frequency radar techniques for measuring ocean wave spectra from satellites

NASA Technical Reports Server (NTRS)

Jackson, F. C.

1980-01-01

Scanning beam microwave radars were used to measure ocean wave directional spectra from satellites. In principle, surface wave spectral resolution in wave number can be obtained using either short pulse (SP) or dual frequency (DF) techniques; in either case, directional resolution obtains naturally as a consequence of a Bragg-like wave front matching. A four frequency moment characterization of backscatter from the near vertical using physical optics in the high frequency limit was applied to an analysis of the SP and DF measurement techniques. The intrinsic electromagnetic modulation spectrum was to the first order in wave steepness proportional to the large wave directional slope spectrum. Harmonic distortion was small and was a minimum near 10 deg incidence. NonGaussian wave statistics can have an effect comparable to that in the second order of scattering from a normally distributed sea surface. The SP technique is superior to the DF technique in terms of measurement signal to noise ratio and contrast ratio.

The prediction, observation and study of long-distant undamped thermal waves generated in pulse radiative processes

NASA Astrophysics Data System (ADS)

Vysotskii, V. I.; Kornilova, A. A.; Vasilenko, A. O.; Krit, T. B.; Vysotskyy, M. V.

2017-07-01

The problems of the existence, generation, propagation and registration of long-distant undamped thermal waves formed in pulse radiative processes have been theoretically analyzed and confirmed experimentally. These waves may be used for the analysis of short-time processes of interaction of particles or electromagnetic fields with different targets. Such undamped waves can only exist in environments with a finite (nonzero) time of local thermal relaxation and their frequencies are determined by this time. The results of successful experiments on the generation and registration of undamped thermal waves at a large distance (up to 2 m) are also presented.

Ablation behaviors of carbon reinforced polymer composites by laser of different operation modes

NASA Astrophysics Data System (ADS)

Wu, Chen-Wu; Wu, Xian-Qian; Huang, Chen-Guang

2015-10-01

Laser ablation mechanism of Carbon Fiber Reinforced Polymer (CFRP) composite is of critical meaning for the laser machining process. The ablation behaviors are investigated on the CFRP laminates subject to continuous wave, long duration pulsed wave and short duration pulsed wave lasers. Distinctive ablation phenomena have been observed and the effects of laser operation modes are discussed. The typical temperature patterns resulted from laser irradiation are computed by finite element analysis and thereby the different ablation mechanisms are interpreted.

Digital Photoplethysmography for Assessment of Arterial Stiffness: Repeatability and Comparison with Applanation Tonometry

PubMed Central

Östling, Gerd; Nilsson, Peter M.

2015-01-01

Introduction Arterial stiffness is an independent risk factor for cardiovascular morbidity and can be assessed by applanation tonometry by measuring pulse wave velocity (PWV) and augmentation index (AIX) by pressure pulse wave analysis (PWA). As an inexpensive and operator independent alternative, photoelectric plethysmography (PPG) has been introduced with analysis of the digital volume pulse wave (DPA) and its second derivatives of wave reflections. Objective The objective was to investigate the repeatability of arterial stiffness parameters measured by digital pulse wave analysis (DPA) and the associations to applanation tonometry parameters. Methods and Results 112 pregnant and non-pregnant individuals of different ages and genders were examined with SphygmoCor arterial wall tonometry and Meridian DPA finger photoplethysmography. Coefficients of repeatability, Bland-Altman plots, intraclass correlation coefficients and correlations to heart rate (HR) and body height were calculated for DPA variables, and the DPA variables were compared to tonometry variables left ventricular ejection time (LVET), PWV and AIX. No DPA variable showed any systematic measurement error or excellent repeatability, but dicrotic index (DI), dicrotic dilatation index (DDI), cardiac ejection elasticity index (EEI), aging index (AI) and second derivatives of the crude pulse wave curve, b/a and e/a, showed good repeatability. Overall, the correlations to AIX were better than to PWV, with correlations coefficients >0.70 for EEI, AI and b/a. Considering the level of repeatability and the correlations to tonometry, the overall best DPA parameters were EEI, AI and b/a. The two pansystolic time parameters, ejection time compensated (ETc) by DPA and LVET by tonometry, showed a significant but weak correlation. Conclusion For estimation of the LV function, ETc, EEI and b/a are suitable, for large artery stiffness EEI, and for small arteries DI and DDI. The only global parameter, AI, showed a high repeatability and the overall best correlations with AIX and PWV. PMID:26291079

The applicability of a material-treatment laser pulse in non-destructive evaluations.

PubMed

Hrovatin, R; Petkovsek, R; Diaci, J; Mozina, J

2006-12-22

A practical optodynamic study was performed to determine the usability of different lengths of laser pulses for the generation of ultrasonic transients in a solid material. The aim of the study was to evaluate the possibility of a dual use for a laser pulse-for laser material processing, on the one hand, and for the ultrasonic wave generation on the other-with both processes being combined on the same production line. The propagation of the laser-generated ultrasonic waves is evaluated by detecting and measuring with a PID-controlled stabilized interferometer. Thus, both systems provided the basic tools, the generation and detection of ultrasonic waves, for an ultrasonic, laser-based, non-destructive material evaluation. The ultrasonic transients generated by 'classical' nanosecond laser pulses were compared with the transients generated by industrial laser pulses with a duration of a few tenths of a microsecond. The experimental results are compared with the results of a time-of-flight analysis that also involved part of a mode-conversion analysis for both regimes in a layered material structure. The differences between the two waveforms were assessed in terms of their visibility, wavelength and resolution. The limit values were calculated and estimated for the laser-pulse parameters, when such pulses are intended for use in an ultrasonic, laser-based, non-destructive evaluation. The possibility of using an industrial marking laser for laser ultrasound generation is thus demonstrated.

Wave Intensity Analysis of Right Ventricular Function during Pulsed Operation of Rotary Left Ventricular Assist Devices.

PubMed

Bouwmeester, J Christopher; Park, Jiheum; Valdovinos, John; Bonde, Pramod

2018-05-29

Changing the speed of left ventricular assist devices (LVADs) cyclically may be useful to restore aortic pulsatility; however, the effects of this pulsation on right ventricular (RV) function are unknown. This study investigates the effects of direct ventricular interaction by quantifying the amount of wave energy created by RV contraction when axial and centrifugal LVADs are used to assist the left ventricle. In 4 anesthetized pigs, pressure and flow were measured in the main pulmonary artery and wave intensity analysis was used to identify and quantify the energy of waves created by the RV. The axial pump depressed the intensity of waves created by RV contraction compared with the centrifugal pump. In both pump designs, there were only minor and variable differences between the continuous and pulsed operation on RV function. The axial pump causes the RV to contract with less energy compared with a centrifugal design. Diminishing the ability of the RV to produce less energy translates to less pressure and flow produced, which may lead to LVAD-induced RV failure. The effects of pulsed LVAD operation on the RV appear to be minimal during acute observation of healthy hearts. Further study is necessary to uncover the effects of other modes of speed modulation with healthy and unhealthy hearts to determine if pulsed operation will benefit patients by reducing LVAD complications.

Molecular isomerization induced by ultrashort infrared pulses. II. Pump-dump isomerization using pairs of time-delayed half-cycle pulses.

PubMed

Uiberacker, Christoph; Jakubetz, Werner

2004-06-22

We investigate population transfer across the barrier in a double-well potential, induced by a pair of time-delayed single-lobe half-cycle pulses. We apply this setup both to a one-dimensional (1D) quartic model potential and to a three-dimensional potential representing HCN-->HNC isomerization. Overall the results for the two systems are similar, although in the 3D system some additional features appear not seen in the 1D case. The generic mechanism of population transfer is the preparation by the pump pulse of a wave packet involving delocalized states above the barrier, followed by the essentially 1D motion of the delocalized part of wave packet across the barrier, and the eventual de-excitation by the dump pulse to localized states in the other well. The correct timing is given by the well-to-well passage time of the wave packet and its recurrence properties, and by the signs of the field lobes which determine the direction and acceleration or deceleration of the wave packet motion. In the 3D system an additional pump-pump-dump mechanism linked to wave packet motion in the reagent well can mediate isomerization. Since the transfer time and the pulse durations are of the same order of magnitude, there is also a marked dependence of the dynamics and the transfer yield on the pulse duration. Our analysis also sheds light on the pronounced carrier envelope phase dependence previously observed for isomerization and molecular dissociation with one-cycle and sub-one-cycle pulses. (c) 2004 American Institute of Physics.

Effect of Wave Reflection and Arterial Stiffness on the Risk of Development of Hypertension in Japanese Men.

PubMed

Tomiyama, Hirofumi; Komatsu, Shunsuke; Shiina, Kazuki; Matsumoto, Chisa; Kimura, Kazutaka; Fujii, Masatsune; Takahashi, Lisa; Chikamori, Taishiro; Yamashina, Akira

2018-05-08

We conducted analyses of repeated-measures data to examine whether pressure wave reflection acts additively or synergistically with arterial stiffness in the pathogenesis of hypertension. In 3172 middle-aged (42±9 years) healthy Japanese men without hypertension at the study baseline, systolic and diastolic blood pressures, brachial-ankle pulse wave velocity, and radial augmentation index were measured annually during a 9-year study period. Of these, 474 participants (15%) developed hypertension by the end of the study period. Binary logistic regression analysis demonstrated significant individual odds ratios for both baseline brachial-ankle pulse wave velocity and radial augmentation index for the development of hypertension. The rate of onset of hypertension during the study period was highest in the participant group with high values for both brachial-ankle pulse wave velocity and radial augmentation index at study baseline (262 of 965 participants: 27%). The generalized estimating equation analysis revealed that both radial augmentation index (estimate=0.06, SE=0.03, P =0.05) and brachial-ankle pulse wave velocity (estimate=0.07×10 -1 , SE=0.02×10 -1 , P <0.01) showed significant longitudinal association with new onset of hypertension, with no significant interaction. In Japanese men, abnormal wave reflection and increased arterial stiffness may be additively associated with the risk of new onset of hypertension. Abnormal wave reflection and elevated central blood pressure may be longitudinally associated with increase in arterial stiffness, and this longitudinal association may be a mechanism underlying the additive effect of these 2 variables on the risk of new onset of hypertension. © 2018 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

Verification of Non-Invasive Blood Glucose Measurement Method Based on Pulse Wave Signal Detected by FBG Sensor System.

PubMed

Kurasawa, Shintaro; Koyama, Shouhei; Ishizawa, Hiroaki; Fujimoto, Keisaku; Chino, Shun

2017-11-23

This paper describes and verifies a non-invasive blood glucose measurement method using a fiber Bragg grating (FBG) sensor system. The FBG sensor is installed on the radial artery, and the strain (pulse wave) that is propagated from the heartbeat is measured. The measured pulse wave signal was used as a collection of feature vectors for multivariate analysis aiming to determine the blood glucose level. The time axis of the pulse wave signal was normalized by two signal processing methods: the shortest-time-cut process and 1-s-normalization process. The measurement accuracy of the calculated blood glucose level was compared with the accuracy of these signal processing methods. It was impossible to calculate a blood glucose level exceeding 200 mg/dL in the calibration curve that was constructed by the shortest-time-cut process. In the 1-s-normalization process, the measurement accuracy of the blood glucose level was improved, and a blood glucose level exceeding 200 mg/dL could be calculated. By verifying the loading vector of each calibration curve to calculate the blood glucose level with a high measurement accuracy, we found the gradient of the peak of the pulse wave at the acceleration plethysmogram greatly affected.

Preliminary body-wave analysis of the St. Elias, Alaska, earthquake of February 28, 1979

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boatwright, J.

1980-04-01

Employing a new technique for the body-wave analysis of shallow-focus earthquakes, we have made a preliminary analysis of the St. Elias, Alaska, earthquake of February 28, 1979, using five long-period P and S waves recorded at three WWSSN stations and at Palisades, New York. Using a well determined focal mechanism and an average source depth of approx. = 11 km, the interference of the depth phases (i.e., pP and sP, or sS) has been deconvolved from the recorded pulse shapes to obtain velocity and displacement pulse shapes as they would appear if the earthquake had occurred within an infinite medium.more » These approximate whole space pulse shapes indicate that the rupture contained three distinct subevents as well as a small initial event which preceded this subevent sequence by about 7 sec. From the pulse rise times of the subevents, their rupture lengths are estimated as 12, 27, and 17 km, assuming that the subevent rupture velocity was 3 km/sec. Overall, the earthquake ruptured approx. = 60 km to the southeast with an average rupture velocity of 2.2 km/sec. The cumulative body-wave moment for the whole event, 1.2 x 10/sup 27/ dyne-cm, is substantially smaller than the surface-wave moments reported by Lahr et al. (1979) of 5 x 10/sup 27/ dyne-cm. The moments of the subevents are estimated to be 0.6, 3.2, and 7.5 x 10/sup 26/ dyne-cm, respectively.« less

Application of the Pulsed Photoacoustic Spectroscopy in Biomedicine

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gutierrez-Juarez, G.; Sims, M. J.; Gupta, S. K.

2008-08-11

The use of optical spectroscopy as a diagnostic tool in biomedical applications and research has grown considerably in the last two decades. One of them is the pulsed photoacoustic or optoacoustic, which promises to be one of the most important tools for disease diagnostic studies, because while most spectroscopies exploit the optical nature of the light-tissue interaction, this field of photoacoustics uses optical energy to generate an acoustic wave which propagates in the tissue environment. The acoustic wave propagation is fundamentally related to various tissue properties and an analysis of the wave dynamics can provide insights into these properties. Thismore » work presents a review on pulsed photoacoustic spectroscopy of several photoacoustic methods to derive information about tissue and tissue phantoms.« less

Regular and singular pulse and front solutions and possible isochronous behavior in the short-pulse equation: Phase-plane, multi-infinite series and variational approaches

NASA Astrophysics Data System (ADS)

Gambino, G.; Tanriver, U.; Guha, P.; Choudhury, A. Ghose; Choudhury, S. Roy

2015-02-01

In this paper we employ three recent analytical approaches to investigate the possible classes of traveling wave solutions of some members of a family of so-called short-pulse equations (SPE). A recent, novel application of phase-plane analysis is first employed to show the existence of breaking kink wave solutions in certain parameter regimes. Secondly, smooth traveling waves are derived using a recent technique to derive convergent multi-infinite series solutions for the homoclinic (heteroclinic) orbits of the traveling-wave equations for the SPE equation, as well as for its generalized version with arbitrary coefficients. These correspond to pulse (kink or shock) solutions respectively of the original PDEs. We perform many numerical tests in different parameter regime to pinpoint real saddle equilibrium points of the corresponding traveling-wave equations, as well as ensure simultaneous convergence and continuity of the multi-infinite series solutions for the homoclinic/heteroclinic orbits anchored by these saddle points. Unlike the majority of unaccelerated convergent series, high accuracy is attained with relatively few terms. And finally, variational methods are employed to generate families of both regular and embedded solitary wave solutions for the SPE PDE. The technique for obtaining the embedded solitons incorporates several recent generalizations of the usual variational technique and it is thus topical in itself. One unusual feature of the solitary waves derived here is that we are able to obtain them in analytical form (within the assumed ansatz for the trial functions). Thus, a direct error analysis is performed, showing the accuracy of the resulting solitary waves. Given the importance of solitary wave solutions in wave dynamics and information propagation in nonlinear PDEs, as well as the fact that not much is known about solutions of the family of generalized SPE equations considered here, the results obtained are both new and timely.

Longitudinal Waves Drive the Solar Cycle

NASA Astrophysics Data System (ADS)

Wagner, Orvin

2000-05-01

In Physics Essays 12: 3-10 I explain the placement of the planets in terms of low velocity waves emitted by the sun. Evidence for the wave pulse generated near the center of the sun is indicated by the initial high latitude sunspots observed on the butterfly diagram. The wave pulse carries charge with it as observed for similar waves in plants (W-waves). For the first half cycle negative charge is carried to the surface of the sun where much of the wave pulse radiates a wave crest into space while the charge slowly redistributes itself. Meanwhile the next wave pulse carrying excess positive charge moves outward. Rotating charge determines the polarity of the sun's magnetic poles so they reverse as the pulse moves outward. The wave pulse, which interacts strongly with force fields, is guided by centripetal force and gravity so that the pulse comes out near the sun's equator. W-waves produce an automatic return wave in the vacuum so that standing waves are produced in the space around the sun providing a template for the formation and stabilization planets. W-waves are hypothesized to provide self organization for both the universe and life. See the

A distributed parameter model of transmission line transformer for high voltage nanosecond pulse generation

NASA Astrophysics Data System (ADS)

Li, Jiangtao; Zhao, Zheng; Li, Longjie; He, Jiaxin; Li, Chenjie; Wang, Yifeng; Su, Can

2017-09-01

A transmission line transformer has potential advantages for nanosecond pulse generation including excellent frequency response and no leakage inductance. The wave propagation process in a secondary mode line is indispensable due to an obvious inside transient electromagnetic transition in this scenario. The equivalent model of the transmission line transformer is crucial for predicting the output waveform and evaluating the effects of magnetic cores on output performance. However, traditional lumped parameter models are not sufficient for nanosecond pulse generation due to the natural neglect of wave propagations in secondary mode lines based on a lumped parameter assumption. In this paper, a distributed parameter model of transmission line transformer was established to investigate wave propagation in the secondary mode line and its influential factors through theoretical analysis and experimental verification. The wave propagation discontinuity in the secondary mode line induced by magnetic cores is emphasized. Characteristics of the magnetic core under a nanosecond pulse were obtained by experiments. Distribution and formation of the secondary mode current were determined for revealing essential wave propagation processes in secondary mode lines. The output waveform and efficiency were found to be affected dramatically by wave propagation discontinuity in secondary mode lines induced by magnetic cores. The proposed distributed parameter model was proved more suitable for nanosecond pulse generation in aspects of secondary mode current, output efficiency, and output waveform. In depth, comprehension of underlying mechanisms and a broader view of the working principle of the transmission line transformer for nanosecond pulse generation can be obtained through this research.

Type 2 diabetes is associated with increased pulse wave velocity measured at different sites of the arterial system but not augmentation index in a Chinese population.

PubMed

Zhang, Minghua; Bai, Yongyi; Ye, Ping; Luo, Leiming; Xiao, Wenkai; Wu, Hongmei; Liu, Dejun

2011-10-01

Patients with type 2 diabetes have increased stiffness of central elastic arteries. However, whether peripheral muscular artery stiffness is equally affected by the disease remains sparsely examined. Moreover, the association between pulse wave velocity (PWV) and augmentation index (AIx) in diabetes is poorly understood. Type 2 diabetes is associated with the alterations in arterial stiffness (PWV and AIx) in a community-based population. A total of 79 Chinese patients with type 2 diabetes and 79 sex-, age- (±3 years), and body mass index- (±2 kg/m(2) ) matched healthy controls were studied. Carotid-femoral pulse wave velocity (CF-PWV), carotid-radial pulse wave velocity (CR-PWV), and carotid-ankle pulse wave velocity (CA-PWV) were calculated from tonometry waveforms and body surface measurements, whereas AIx was assessed using pulse wave analyses. In univariate analysis, patients with type 2 diabetes showed increased CF-PWV (P < 0.001), CR-PWV (P = 0.012), and CA-PWV (P = 0.016), and lower AIx (P = 0.017) than the control group. In multiple linear regression models adjusting for covariates, type 2 diabetes remained a significant determinant of CF-PWV. Fasting glucose was associated with CR-PWV but was not related to CA-PWV or AIx. Our findings suggest that patients with type 2 diabetes have increased central and peripheral artery stiffness, but preserved AIx compared to controls. Diabetes was a predictor of central artery stiffness, and glucose was a determinant of peripheral artery stiffness. © 2011 Wiley Periodicals, Inc.

A distributed parameter model of transmission line transformer for high voltage nanosecond pulse generation.

PubMed

Li, Jiangtao; Zhao, Zheng; Li, Longjie; He, Jiaxin; Li, Chenjie; Wang, Yifeng; Su, Can

2017-09-01

A transmission line transformer has potential advantages for nanosecond pulse generation including excellent frequency response and no leakage inductance. The wave propagation process in a secondary mode line is indispensable due to an obvious inside transient electromagnetic transition in this scenario. The equivalent model of the transmission line transformer is crucial for predicting the output waveform and evaluating the effects of magnetic cores on output performance. However, traditional lumped parameter models are not sufficient for nanosecond pulse generation due to the natural neglect of wave propagations in secondary mode lines based on a lumped parameter assumption. In this paper, a distributed parameter model of transmission line transformer was established to investigate wave propagation in the secondary mode line and its influential factors through theoretical analysis and experimental verification. The wave propagation discontinuity in the secondary mode line induced by magnetic cores is emphasized. Characteristics of the magnetic core under a nanosecond pulse were obtained by experiments. Distribution and formation of the secondary mode current were determined for revealing essential wave propagation processes in secondary mode lines. The output waveform and efficiency were found to be affected dramatically by wave propagation discontinuity in secondary mode lines induced by magnetic cores. The proposed distributed parameter model was proved more suitable for nanosecond pulse generation in aspects of secondary mode current, output efficiency, and output waveform. In depth, comprehension of underlying mechanisms and a broader view of the working principle of the transmission line transformer for nanosecond pulse generation can be obtained through this research.

Acute effects of ultrafiltration on aortic mechanical properties determined by measurement of pulse wave velocity and pulse propagation time in hemodialysis patients

PubMed Central

Yıldız, Banu Şahin; Şahin, Alparslan; Aladağ, Nazire Başkurt; Arslan, Gülgün; Kaptanoğulları, Hakan; Akın, İbrahim; Yıldız, Mustafa

2015-01-01

Objective: The effects of acute hemodialysis session on pulse wave velocity are conflicting. The aim of the current study was to assess the acute effects of ultrafiltration on the aortic mechanical properties using carotid-femoral (aortic) pulse wave velocity and pulse propagation time. Methods: A total of 26 (12 women, 14 men) consecutive patients on maintenance hemodialysis (mean dialysis duration: 40.7±25.6 (4-70) months) and 29 healthy subjects (13 women, 16 men) were included in this study. Baseline blood pressure, carotid-femoral (aortic) pulse wave velocity, and pulse propagation time were measured using a Complior Colson device (Createch Industrie, France) before and immediately after the end of the dialysis session. Results: While systolic blood pressure, diastolic blood pressure, mean blood pressure, pulse pressure, and pulse wave velocity were significantly higher in patients on hemodialysis than in healthy subjects, pulse propagation time was significantly higher in healthy subjects. Although body weight, systolic blood pressure, diastolic blood pressure, mean blood pressure, pulse pressure, and pulse wave velocity were significantly decreased, heart rate and pulse propagation time were significantly increased after ultrafiltration. There was a significant positive correlation between pulse wave velocity and age, body height, waist circumference, systolic blood pressure, diastolic blood pressure, mean blood pressure, pulse pressure, and heart rate. Conclusion: Although hemodialysis treatment may chronically worsen aortic mechanical properties, ultrafiltration during hemodialysis may significantly improve aortic pulse wave velocity, which is inversely related to aortic distensibility and pulse propagation time. PMID:25413228

Changes in Central Aortic Pressure Levels, Wave Components and Determinants Associated with High Peripheral Blood Pressure States in Childhood: Analysis of Hypertensive Phenotype.

PubMed

García-Espinosa, Victoria; Curcio, Santiago; Marotta, Marco; Castro, Juan M; Arana, Maite; Peluso, Gonzalo; Chiesa, Pedro; Giachetto, Gustavo; Bia, Daniel; Zócalo, Yanina

2016-10-01

The aims were to determine whether children's high peripheral blood pressure states (HBP) are associated with increased central aortic blood pressure (BP) and to characterize hemodynamic and vascular changes associated with HBP in terms of changes in cardiac output (stroke volume, SV), arterial stiffness (aortic pulse wave velocity, PWV), peripheral vascular resistances (PVR) and net and relative contributions of reflected waves to the aortic pulse amplitude. We included 154 subjects (mean age 11; range 4-16 years) assigned to one of two groups: normal peripheral BP (NBP, n = 101), defined as systolic and diastolic BP < 90th percentile, or high BP (HBP, n = 53), defined as average systolic and/or diastolic BP levels ≥90th percentile (curves for sex, age and body height). The HBP group included children with hypertensive and pre-hypertensive BP levels. After a first analysis, groups were compared excluding obese and dyslipidemic children. Peripheral and central aortic BP, PWV and pulse wave-derived parameters (augmentation index, forward and backward wave components' amplitude) were measured using gold-standard techniques, applanation tonometry (SphygmoCor) and oscillometry (Mobil-O-Graph). Independent of the presence of dyslipidemia and/or obesity, aortic systolic and pulse BP were higher in HBP than in NBP children. The increase in central BP could not be explained by an increase in the relative contribution of reflections to the aortic pressure wave, higher PVR or by an augmented peripheral reflection coefficient. Instead, the rise in central BP would be explained by an increase in the amplitude of both incident and reflected wave components.

Modeling digital pulse waveforms by solving one-dimensional Navier-stokes equations.

PubMed

Fedotov, Aleksandr A; Akulova, Anna S; Akulov, Sergey A

2016-08-01

Mathematical modeling for composition distal arterial pulse wave in the blood vessels of the upper limbs was considered. Formation of distal arterial pulse wave is represented as a composition of forward and reflected pulse waves propagating along the arterial vessels. The formal analogy between pulse waves propagation along the human arterial system and the propagation of electrical oscillations in electrical transmission lines with distributed parameters was proposed. Dependencies of pulse wave propagation along the human arterial system were obtained by solving the one-dimensional Navier-Stokes equations for a few special cases.

An analysis of beam parameters on proton-acoustic waves through an analytic approach.

PubMed

Kipergil, Esra Aytac; Erkol, Hakan; Kaya, Serhat; Gulsen, Gultekin; Unlu, Mehmet Burcin

2017-06-21

It has been reported that acoustic waves are generated when a high-energy pulsed proton beam is deposited in a small volume within tissue. One possible application of proton-induced acoustics is to get real-time feedback for intra-treatment adjustments by monitoring such acoustic waves. A high spatial resolution in ultrasound imaging may reduce proton range uncertainty. Thus, it is crucial to understand the dependence of the acoustic waves on the proton beam characteristics. In this manuscript, firstly, an analytic solution for the proton-induced acoustic wave is presented to reveal the dependence of the signal on the beam parameters; then it is combined with an analytic approximation of the Bragg curve. The influence of the beam energy, pulse duration and beam diameter variation on the acoustic waveform are investigated. Further analysis is performed regarding the Fourier decomposition of the proton-acoustic signals. Our results show that the smaller spill time of the proton beam upsurges the amplitude of the acoustic wave for a constant number of protons, which is hence beneficial for dose monitoring. The increase in the energy of each individual proton in the beam leads to the spatial broadening of the Bragg curve, which also yields acoustic waves of greater amplitude. The pulse duration and the beam width of the proton beam do not affect the central frequency of the acoustic wave, but they change the amplitude of the spectral components.

Full Spectrum Conversion Using Traveling Pulse Wave Quantization

DTIC Science & Technology

2017-03-01

Full Spectrum Conversion Using Traveling Pulse Wave Quantization Michael S. Kappes Mikko E. Waltari IQ-Analog Corporation San Diego, California...temporal-domain quantization technique called Traveling Pulse Wave Quantization (TPWQ). Full spectrum conversion is defined as the complete...pulse width measurements that are continuously generated hence the name “traveling” pulse wave quantization. Our TPWQ-based ADC is composed of a

Influence of Individual Differences on the Calculation Method for FBG-Type Blood Pressure Sensors

PubMed Central

Koyama, Shouhei; Ishizawa, Hiroaki; Fujimoto, Keisaku; Chino, Shun; Kobayashi, Yuka

2016-01-01

In this paper, we propose a blood pressure calculation and associated measurement method that by using a fiber Bragg grating (FBG) sensor. There are several points at which the pulse can be measured on the surface of the human body, and when a FBG sensor located at any of these points, the pulse wave signal can be measured. The measured waveform is similar to the acceleration pulse wave. The pulse wave signal changes depending on several factors, including whether or not the individual is healthy and/or elderly. The measured pulse wave signal can be used to calculate the blood pressure using a calibration curve, which is constructed by a partial least squares (PLS) regression analysis using a reference blood pressure and the pulse wave signal. In this paper, we focus on the influence of individual differences from calculated blood pressure based on each calibration curve. In our study, the calculated blood pressure from both the individual and overall calibration curves were compared, and our results show that the calculated blood pressure based on the overall calibration curve had a lower measurement accuracy than that based on an individual calibration curve. We also found that the influence of the individual differences on the calculated blood pressure when using the FBG sensor method were very low. Therefore, the FBG sensor method that we developed for measuring the blood pressure was found to be suitable for use by many people. PMID:28036015

Influence of Individual Differences on the Calculation Method for FBG-Type Blood Pressure Sensors.

PubMed

Koyama, Shouhei; Ishizawa, Hiroaki; Fujimoto, Keisaku; Chino, Shun; Kobayashi, Yuka

2016-12-28

In this paper, we propose a blood pressure calculation and associated measurement method that by using a fiber Bragg grating (FBG) sensor. There are several points at which the pulse can be measured on the surface of the human body, and when a FBG sensor located at any of these points, the pulse wave signal can be measured. The measured waveform is similar to the acceleration pulse wave. The pulse wave signal changes depending on several factors, including whether or not the individual is healthy and/or elderly. The measured pulse wave signal can be used to calculate the blood pressure using a calibration curve, which is constructed by a partial least squares (PLS) regression analysis using a reference blood pressure and the pulse wave signal. In this paper, we focus on the influence of individual differences from calculated blood pressure based on each calibration curve. In our study, the calculated blood pressure from both the individual and overall calibration curves were compared, and our results show that the calculated blood pressure based on the overall calibration curve had a lower measurement accuracy than that based on an individual calibration curve. We also found that the influence of the individual differences on the calculated blood pressure when using the FBG sensor method were very low. Therefore, the FBG sensor method that we developed for measuring the blood pressure was found to be suitable for use by many people.

Pulse Wave Velocity Predicts Response to Renal Denervation in Isolated Systolic Hypertension.

PubMed

Fengler, Karl; Rommel, Karl-Philipp; Hoellriegel, Robert; Blazek, Stephan; Besler, Christian; Desch, Steffen; Schuler, Gerhard; Linke, Axel; Lurz, Philipp

2017-05-17

Renal sympathetic denervation seems to be less effective as a treatment for hypertension in patients with isolated systolic hypertension, a condition associated with elevated central arterial stiffness. Because isolated systolic hypertension can also be caused by wave reflection or increased cardiac output, a more differentiated approach might improve patient preselection for renal sympathetic denervation. We sought to evaluate the additional predictive value of invasive pulse wave velocity for response to renal sympathetic denervation in patients with combined versus isolated systolic hypertension. Patients scheduled for renal sympathetic denervation underwent additional invasive measurement of pulse wave velocity and pulse pressure before denervation. Blood pressure was assessed via ambulatory measurement at baseline and after 3 months. In total 109 patients (40 patients with isolated systolic hypertension) were included in our analysis. After 3 months, blood pressure reduction was more pronounced among patients with combined hypertension compared with patients with isolated systolic hypertension (systolic 24-hour average 9.3±10.5 versus 5.0±11.5 mm Hg, P =0.046). However, when stratifying patients with isolated systolic hypertension by invasive pulse wave velocity, patients in the lowest tertile of pulse wave velocity had comparable blood pressure reduction (12.1±12.6 mm Hg, P =0.006) despite lower baseline blood pressure than patients with combined hypertension (systolic 24-hour average 154.8±12.5 mm Hg in combined hypertension versus 141.2±8.1, 148.4±10.9, and 150.5±12.7 mm Hg, respectively, by tertiles of pulse wave velocity, P =0.002). Extended assessment of arterial stiffness can help improve patient preselection for renal sympathetic denervation and identify a subgroup of isolated systolic hypertension patients who benefit from sympathetic modulation. © 2017 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

Generation and evolution of mode-locked noise-like square-wave pulses in a large-anomalous-dispersion Er-doped ring fiber laser.

PubMed

Liu, Jun; Chen, Yu; Tang, Pinghua; Xu, Changwen; Zhao, Chujun; Zhang, Han; Wen, Shuangchun

2015-03-09

In a passively mode-locked Erbium-doped fiber laser with large anomalous-dispersion, we experimentally demonstrate the formation of noise-like square-wave pulse, which shows quite different features from conventional dissipative soliton resonance (DSR). The corresponding temporal and spectral characteristics of a variety of operation states, including Q-switched mode-locking, continuous-wave mode-locking and Raman-induced noise-like pulse near the lasing threshold, are also investigated. Stable noise-like square-wave mode-locked pulses can be obtained at a fundamental repetition frequency of 195 kHz, with pulse packet duration tunable from 15 ns to 306 ns and per-pulse energy up to 200 nJ. By reducing the linear cavity loss, stable higher-order harmonic mode-locking had also been observed, with pulse duration ranging from 37 ns at the 21st order harmonic wave to 320 ns at the fundamental order. After propagating along a piece of long telecom fiber, the generated square-wave pulses do not show any obvious change, indicating that the generated noise-like square-wave pulse can be considered as high-energy pulse packet for some promising applications. These experimental results should shed some light on the further understanding of the mechanism and characteristics of noise-like square-wave pulses.

Analysis of THG modes for femtosecond laser pulse

NASA Astrophysics Data System (ADS)

Trofimov, Vyacheslav A.; Sidorov, Pavel S.

2017-05-01

THG is used nowadays in many practical applications such as a substance diagnostics, and biological objects imaging, and etc. With developing of new materials and technology (for example, photonic crystal) an attention to THG process analysis grow. Therefore, THG features understanding are a modern problem. Early we have developed new analytical approach based on using the problem invariant for analytical solution construction of the THG process. It should be stressed that we did not use a basic wave non-depletion approximation. Nevertheless, a long pulse duration approximation and plane wave approximation has applied. The analytical solution demonstrates, in particular, an optical bistability property (and may other regimes of frequency tripling) for the third harmonic generation process. But, obviously, this approach does not reflect an influence of a medium dispersion on the frequency tripling. Therefore, in this paper we analyze THG efficiency of a femtosecond laser pulse taking into account a second order dispersion affect as well as self- and crossmodulation of the interacting waves affect on the frequency conversion process. Analysis is made using a computer simulation on the base of Schrödinger equations describing the process under consideration.

Directional spectra of ocean waves from microwave backscatter: A physical optics solution with application to the short-pulse and two-frequency measurement techniques

NASA Technical Reports Server (NTRS)

Jackson, F. C.

1979-01-01

Two simple microwave radar techniques that are potentially capable of providing routine satellite measurements of the directional spectrum of ocean waves were developed. One technique, the short pulse technique, makes use of very short pulses to resolve ocean surface wave contrast features in the range direction; the other technique, the two frequency correlation technique makes use of coherency in the transmitted waveform to detect the large ocean wave contrast modulation as a beat or mixing frequency in the power backscattered at two closely separated microwave frequencies. A frequency domain analysis of the short pulse and two frequency systems shows that the two measurement systems are essentially duals; they each operate on the generalized (three frequency) fourth-order statistical moment of the surface transfer function in different, but symmetrical ways, and they both measure the same directional contrast modulation spectrum. A three dimensional physical optics solution for the fourth-order moment was obtained for backscatter in the near vertical, specular regime, assuming Gaussian surface statistics.

Wearable sensor glove based on conducting fabric using electrodermal activity and pulse-wave sensors for e-health application.

PubMed

Lee, Youngbum; Lee, Byungwoo; Lee, Myoungho

2010-03-01

Improvement of the quality and efficiency of health in medicine, both at home and the hospital, calls for improved sensors that might be included in a common carrier such as a wearable sensor device to measure various biosignals and provide healthcare services that use e-health technology. Designed to be user-friendly, smart clothes and gloves respond well to the end users for health monitoring. This study describes a wearable sensor glove that is equipped with an electrodermal activity (EDA) sensor, pulse-wave sensor, conducting fabric, and an embedded system. The EDA sensor utilizes the relationship between drowsiness and the EDA signal. The EDA sensors were made using a conducting fabric instead of silver chloride electrodes, as a more practical and practically wearable device. The pulse-wave sensor measurement system, which is widely applied in oriental medicinal practices, is also a strong element in e-health monitoring systems. The EDA and pulse-wave signal acquisition module was constructed by connecting the sensor to the glove via a conductive fabric. The signal acquisition module is then connected to a personal computer that displays the results of the EDA and pulse-wave signal processing analysis and gives accurate feedback to the user. This system is designed for a number of applications for the e-health services, including drowsiness detection and oriental medicine.

Nonlinear structures: Cnoidal, soliton, and periodical waves in quantum semiconductor plasma

NASA Astrophysics Data System (ADS)

Tolba, R. E.; El-Bedwehy, N. A.; Moslem, W. M.; El-Labany, S. K.; Yahia, M. E.

2016-01-01

Properties and emerging conditions of various nonlinear acoustic waves in a three dimensional quantum semiconductor plasma are explored. A plasma fluid model characterized by degenerate pressures, exchange correlation, and quantum recoil forces is established and solved. Our analysis approach is based on the reductive perturbation theory for deriving the Kadomtsev-Petviashvili equation from the fluid model and solving it by using Painlevé analysis to come up with different nonlinear solutions that describe different pulse profiles such as cnoidal, soliton, and periodical pulses. The model is then employed to recognize the possible perturbations in GaN semiconductor.

Nonlinear structures: Cnoidal, soliton, and periodical waves in quantum semiconductor plasma

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tolba, R. E., E-mail: tolba-math@yahoo.com; El-Bedwehy, N. A., E-mail: nab-elbedwehy@yahoo.com; Moslem, W. M., E-mail: wmmoslem@hotmail.com

2016-01-15

Properties and emerging conditions of various nonlinear acoustic waves in a three dimensional quantum semiconductor plasma are explored. A plasma fluid model characterized by degenerate pressures, exchange correlation, and quantum recoil forces is established and solved. Our analysis approach is based on the reductive perturbation theory for deriving the Kadomtsev-Petviashvili equation from the fluid model and solving it by using Painlevé analysis to come up with different nonlinear solutions that describe different pulse profiles such as cnoidal, soliton, and periodical pulses. The model is then employed to recognize the possible perturbations in GaN semiconductor.

High-resolution studies of the HF ionospheric modification interaction region

NASA Technical Reports Server (NTRS)

Duncan, L. M.; Sheerin, J. P.

1985-01-01

The use of the pulse edge analysis technique to explain ionospheric modifications caused by high-power HF radio waves is discussed. The technique, implemented at the Arecibo Observatory, uses long radar pulses and very rapid data sampling. A comparison of the pulse leading and trailing edge characteristics is obtained and the comparison is used to estimate the relative changes in the interaction region height and layer width; an example utilizing this technique is provided. Main plasma line overshoot and miniovershoot were studied from the pulse edge observations; the observations at various HF pulsings and radar resolutions are graphically presented. From the pulse edge data the development and the occurrence of main plasma line overshoot and miniovershoot are explained. The theories of soliton formation and collapse, wave ducting, profile modification, and parametric instabilities are examined as a means of explaining main plasma line overshoots and miniovershoots.

Uric Acid Level Has a J-Shaped Association with Arterial Stiffness in Korean Postmenopausal Women.

PubMed

Lee, Hyungbin; Jung, Young-Hyo; Kwon, Yu-Jin; Park, Byoungjin

2017-11-01

Uric acid has been reported to function both as an oxidant or antioxidant depending on the context. A previous study in the Korean population reported a positive linear association between serum uric acid level and arterial stiffness in men, but little is known about how serum uric acid level is related to the risk of increased arterial stiffness in Korean postmenopausal women. We performed a cross-sectional study of 293 subjects who participated in a health examination program run by the health promotion center of Gangnam Severance Hospital between October 2007 and July 2010. High brachial-ankle pulse wave velocity was defined as a brachial-ankle pulse wave velocity of more than 1,450 cm/s. The odds ratios (ORs) for high brachial-ankle pulse wave velocity were calculated using multivariate logistic regression analysis across uric acid quartiles after adjusting for other indicators of cardiovascular risk. The 293 postmenopausal women were divided into quartiles according to uric acid level. The mean brachial-ankle pulse wave velocity values of each quartile were as follows: Q1, 1,474 cm/s; Q2, 1,375 cm/s; Q3, 1,422 cm/s; Q4, 1,528 cm/s. The second quartile was designated as the control group based on mean brachial-ankle pulse wave velocity value. Multivariate adjusted ORs (95% confidence intervals) for brachial-ankle pulse wave velocity across the uric acid quartiles were 2.642 (Q1, 1.095-6.3373), 1.00, 4.305 (Q3, 1.798-10.307), and 4.375 (Q4, 1.923-9.949), after adjusting for confounding variables. Serum uric acid level has a J-shaped association with arterial stiffness in Korean postmenopausal women.

Single pulse analysis of intracranial pressure for a hydrocephalus implant.

PubMed

Elixmann, I M; Hansinger, J; Goffin, C; Antes, S; Radermacher, K; Leonhardt, S

2012-01-01

The intracranial pressure (ICP) waveform contains important diagnostic information. Changes in ICP are associated with changes of the pulse waveform. This change has explicitly been observed in 13 infusion tests by analyzing 100 Hz ICP data. An algorithm is proposed which automatically extracts the pulse waves and categorizes them into predefined patterns. A developed algorithm determined 88 %±8 % (mean ±SD) of all classified pulse waves correctly on predefined patterns. This algorithm has low computational cost and is independent of a pressure drift in the sensor by using only the relationship between special waveform characteristics. Hence, it could be implemented on a microcontroller of a future electromechanic hydrocephalus shunt system to control the drainage of cerebrospinal fluid (CSF).

Note: A novel method for generating multichannel quasi-square-wave pulses.

PubMed

Mao, C; Zou, X; Wang, X

2015-08-01

A 21-channel quasi-square-wave nanosecond pulse generator was constructed. The generator consists of a high-voltage square-wave pulser and a channel divider. Using an electromagnetic relay as a switch and a 50-Ω polyethylene cable as a pulse forming line, the high-voltage pulser produces a 10-ns square-wave pulse of 1070 V. With a specially designed resistor-cable network, the channel divider divides the high-voltage square-wave pulse into 21 identical 10-ns quasi-square-wave pulses of 51 V, exactly equal to 1070 V/21. The generator can operate not only in a simultaneous mode but also in a delay mode if the cables in the channel divider are different in length.

Experimental study on the pressure wave propagation in the artificial arterial tree in brain

NASA Astrophysics Data System (ADS)

Shimada, Shinya; Tsurusaki, Ryo; Iwase, Fumiaki; Matsukawa, Mami; Lagrée, Pierre-Yves

2018-07-01

A pulse wave measurement is effective for the early detection of arteriosclerosis. The pulse wave consists of incident and reflected waves. The reflected wave of the pulse wave measured at the left common carotid artery seems to originate from the vascular beds in the brain. The aim of this study is to know if the reflected waves from the occlusions in cerebral arteries can affect the pulse waveform. The artificial arterial tree in the brain was therefore fabricated using polyurethane tubes. After investigating the effects of the bifurcation angle on the pulse waveform, we attempted to confirm whether the reflected waves from occlusions in the artificial arterial tree in the brain can be experimentally measured at the left common carotid artery. Results indicate that the bifurcation angle did not affect the pulse waveform, and that the reflected wave from an occlusion with a diameter of more than 1 mm in the brain could be observed.

Localized wave pulses in the keyport experiment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chambers, D.H.; Lewis, D.K.

1998-02-17

Localized wave (LW) pulses were produced using a standard Navy array in the anechoic tank at Navy Underwater Weapons Center (NUWC) Keyport. The LW pulses used were the MPS pulse first derived by Ziolkowski, and a new type of pulse based on a superposition of Gaussian beam modes. This new type is motivated by a desire to make a comparison of the MPS pulse with another broad band pulse built from solutions to the wave equation. The superposed Gaussian pulse can be described by parameters which are analogous to those describing the MPS pulse. We compare the directivity patternsand themore » axial energy decay between the pulses. We find the behavior of the pulses to be similar so that the superposed Gaussian could be another candidate in the class of low diffractive pulses known as localized waves.« less

Vibrational Responses Of Structures To Impulses

NASA Technical Reports Server (NTRS)

Zak, Michail A.

1990-01-01

Report discusses propagation of vibrations in structure in response to impulsive and/or concentrated loads. Effects of pulsed loads treated by analyzing propagation of characteristic vibrational waves explicitly through each member of structure. This wave-front analysis used in combination with usual finite-element modal analysis to obtain more accurate representation of overall vibrational behavior.

10 Gb/s optical carrier distributed network with W-band (0.1 THz) short-reach wireless communication system

NASA Astrophysics Data System (ADS)

Chow, C. W.; Yang, L. G.; Yeh, C. H.; Huang, C. B.; Shi, J. W.; Pan, C. L.

2012-10-01

Millimeter-wave (mm-wave) operated in W-band (75 GHz-0.11 THz) is of particular interests, since this frequency band can carry signals at much higher data rates. We demonstrate a 10 Gb/s optical carrier-distributed network with the wireless communication system. The mm-wave signal at carrier frequency of 0.1 THz is generated by a high speed near-ballistic uni-traveling carrier photodiode (NBUTC-PD) based transmitter (Tx), which is optically excited by optical short pulses. The optical pulse source is produced from a self-developed photonic mm-wave waveform generator (PMWG), which allows spectral line-by-line pulse shaping. Hence these optical pulses have high tolerance to fiber chromatic dispersion. The W-band 10 Gb/s wireless data is transmitted and received via a pair of horn antennas. The received 10 Gb/s data is envelope-detected and then used to drive an optical modulator at the remote antenna unit (RAU) to produce the upstream signal sending back to the central office (CO). 20 km single mode fiber (SMF) error free transmission is achieved. Analysis about the optimum repetition rate of the optical pulse source and the transmission performance of the upstream signal are also performed and discussed.

Blood pulse wave velocity measured by photoacoustic microscopy

NASA Astrophysics Data System (ADS)

Yeh, Chenghung; Hu, Song; Maslov, Konstantin; Wang, Lihong V.

2013-03-01

Blood pulse wave velocity (PWV) is an important indicator for vascular stiffness. In this letter, we present electrocardiogram-synchronized photoacoustic microscopy for in vivo noninvasive quantification of the PWV in the peripheral vessels of mice. Interestingly, strong correlation between blood flow speed and ECG were clearly observed in arteries but not in veins. PWV is measured by the pulse travel time and the distance between two spot of a chose vessel, where simultaneously recorded electrocardiograms served as references. Statistical analysis shows a linear correlation between the PWV and the vessel diameter, which agrees with known physiology. Keywords: photoacoustic microscopy, photoacoustic spectroscopy, bilirubin, scattering medium.

Influence of the carrier-envelope phase of few-cycle pulses on ponderomotive surface-plasmon electron acceleration.

PubMed

Irvine, S E; Dombi, P; Farkas, Gy; Elezzabi, A Y

2006-10-06

Control over basic processes through the electric field of a light wave can lead to new knowledge of fundamental light-matter interaction phenomena. We demonstrate, for the first time, that surface-plasmon (SP) electron acceleration can be coherently controlled through the carrier-envelope phase (CEP) of an excitation optical pulse. Analysis indicates that the physical origin of the CEP sensitivity arises from the electron's ponderomotive interaction with the oscillating electromagnetic field of the SP wave. The ponderomotive electron acceleration mechanism provides sensitive (nJ energies), high-contrast, single-shot CEP measurement capability of few-cycle laser pulses.

Tailored pump compensation for Brillouin optical time-domain analysis with distributed Brillouin amplification.

PubMed

Kim, Young Hoon; Song, Kwang Yong

2017-06-26

A Brillouin optical time domain analysis (BOTDA) system utilizing tailored compensation for the propagation loss of the pump pulse is demonstrated for long-range and high-resolution distributed sensing. A continuous pump wave for distributed Brillouin amplification (DBA pump) of the pump pulse co-propagates with the probe wave, where gradual variation of the spectral width is additionally introduced to the DBA pump to obtain a uniform Brillouin gain along the position. In the experimental confirmation, a distributed strain measurement along a 51.2 km fiber under test is presented with a spatial resolution of 20 cm, in which the measurement error (σ) of less than 1.45 MHz and the near-constant Brillouin gain of the probe wave are maintained throughout the fiber.

Response of a hypersonic boundary layer to freestream pulse acoustic disturbance.

PubMed

Wang, Zhenqing; Tang, Xiaojun; Lv, Hongqing

2014-01-01

The response of hypersonic boundary layer over a blunt wedge to freestream pulse acoustic disturbance was investigated. The stability characteristics of boundary layer for freestream pulse wave and continuous wave were analyzed comparatively. Results show that freestream pulse disturbance changes the thermal conductivity characteristics of boundary layer. For pulse wave, the number of main disturbance clusters decreases and the frequency band narrows along streamwise. There are competition and disturbance energy transfer among different modes in boundary layer. The dominant mode of boundary layer has an inhibitory action on other modes. Under continuous wave, the disturbance modes are mainly distributed near fundamental and harmonic frequencies, while under pulse wave, the disturbance modes are widely distributed in different modes. For both pulse and continuous waves, most of disturbance modes slide into a lower-growth or decay state in downstream, which is tending towards stability. The amplitude of disturbance modes in boundary layer under continuous wave is considerably larger than pulse wave. The growth rate for the former is also considerably larger than the later the disturbance modes with higher growth are mainly distributed near fundamental and harmonic frequencies for the former, while the disturbance modes are widely distributed in different frequencies for the latter.

Response of a Hypersonic Boundary Layer to Freestream Pulse Acoustic Disturbance

PubMed Central

Wang, Zhenqing; Tang, Xiaojun; Lv, Hongqing

2014-01-01

The response of hypersonic boundary layer over a blunt wedge to freestream pulse acoustic disturbance was investigated. The stability characteristics of boundary layer for freestream pulse wave and continuous wave were analyzed comparatively. Results show that freestream pulse disturbance changes the thermal conductivity characteristics of boundary layer. For pulse wave, the number of main disturbance clusters decreases and the frequency band narrows along streamwise. There are competition and disturbance energy transfer among different modes in boundary layer. The dominant mode of boundary layer has an inhibitory action on other modes. Under continuous wave, the disturbance modes are mainly distributed near fundamental and harmonic frequencies, while under pulse wave, the disturbance modes are widely distributed in different modes. For both pulse and continuous waves, most of disturbance modes slide into a lower-growth or decay state in downstream, which is tending towards stability. The amplitude of disturbance modes in boundary layer under continuous wave is considerably larger than pulse wave. The growth rate for the former is also considerably larger than the later the disturbance modes with higher growth are mainly distributed near fundamental and harmonic frequencies for the former, while the disturbance modes are widely distributed in different frequencies for the latter. PMID:24737993

Association of Brachial-Ankle Pulse Wave Velocity with Asymptomatic Intracranial Arterial Stenosis in Hypertension Patients.

PubMed

Wang, Yan; Zhang, Jin; Qain, Yuesheng; Tang, Xiaofeng; Ling, Huawei; Chen, Kemin; Li, Yan; Gao, Pingjin; Zhu, Dingliang

2016-08-01

Intracranial arterial stenosis is a common cause of ischemic stroke in Asians. We therefore sought to explore the relationship of brachial-ankle pulse wave velocity and intracranial arterial stenosis in 834 stroke-free hypertensive patients. Intracranial arterial stenosis was evaluated through computerized tomographic angiography. Brachial-ankle pulse wave velocity was measured by an automated cuff device. The top decile of brachial-ankle pulse wave velocity was significantly associated with intracranial arterial stenosis (P = .027, odds ratio = 1.82; 95% confidence interval: 1.07-3.10). The patients with the top decile of brachial-ankle pulse wave velocity showed 56% higher risk for the presence of intracranial arterial stenosis to the whole population, which was more significant in patients younger than 65 years old. We also found that brachial-ankle pulse wave velocity related to both intracranial arterial stenosis and homocysteine. Our study showed the association of brachial-ankle pulse wave velocity with asymptomatic intracranial arterial stenosis in hypertension patients, especially in relative younger subjects. Brachial-ankle pulse wave velocity might be a relatively simple and repeatable measurement to detect hypertension patients in high risk of intracranial arterial stenosis. Copyright © 2016. Published by Elsevier Inc.

Resting spontaneous baroreflex sensitivity and cardiac autonomic control in anabolic androgenic steroid users

PubMed Central

dos Santos, Marcelo R.; Sayegh, Ana L.C.; Armani, Rafael; Costa-Hong, Valéria; de Souza, Francis R.; Toschi-Dias, Edgar; Bortolotto, Luiz A.; Yonamine, Mauricio; Negrão, Carlos E.; Alves, Maria-Janieire N.N.

2018-01-01

OBJECTIVES: Misuse of anabolic androgenic steroids in athletes is a strategy used to enhance strength and skeletal muscle hypertrophy. However, its abuse leads to an imbalance in muscle sympathetic nerve activity, increased vascular resistance, and increased blood pressure. However, the mechanisms underlying these alterations are still unknown. Therefore, we tested whether anabolic androgenic steroids could impair resting baroreflex sensitivity and cardiac sympathovagal control. In addition, we evaluate pulse wave velocity to ascertain the arterial stiffness of large vessels. METHODS: Fourteen male anabolic androgenic steroid users and 12 nonusers were studied. Heart rate, blood pressure, and respiratory rate were recorded. Baroreflex sensitivity was estimated by the sequence method, and cardiac autonomic control by analysis of the R-R interval. Pulse wave velocity was measured using a noninvasive automatic device. RESULTS: Mean spontaneous baroreflex sensitivity, baroreflex sensitivity to activation of the baroreceptors, and baroreflex sensitivity to deactivation of the baroreceptors were significantly lower in users than in nonusers. In the spectral analysis of heart rate variability, high frequency activity was lower, while low frequency activity was higher in users than in nonusers. Moreover, the sympathovagal balance was higher in users. Users showed higher pulse wave velocity than nonusers showing arterial stiffness of large vessels. Single linear regression analysis showed significant correlations between mean blood pressure and baroreflex sensitivity and pulse wave velocity. CONCLUSIONS: Our results provide evidence for lower baroreflex sensitivity and sympathovagal imbalance in anabolic androgenic steroid users. Moreover, anabolic androgenic steroid users showed arterial stiffness. Together, these alterations might be the mechanisms triggering the increased blood pressure in this population. PMID:29791601

Resting spontaneous baroreflex sensitivity and cardiac autonomic control in anabolic androgenic steroid users.

PubMed

Santos, Marcelo R Dos; Sayegh, Ana L C; Armani, Rafael; Costa-Hong, Valéria; Souza, Francis R de; Toschi-Dias, Edgar; Bortolotto, Luiz A; Yonamine, Mauricio; Negrão, Carlos E; Alves, Maria-Janieire N N

2018-05-21

Misuse of anabolic androgenic steroids in athletes is a strategy used to enhance strength and skeletal muscle hypertrophy. However, its abuse leads to an imbalance in muscle sympathetic nerve activity, increased vascular resistance, and increased blood pressure. However, the mechanisms underlying these alterations are still unknown. Therefore, we tested whether anabolic androgenic steroids could impair resting baroreflex sensitivity and cardiac sympathovagal control. In addition, we evaluate pulse wave velocity to ascertain the arterial stiffness of large vessels. Fourteen male anabolic androgenic steroid users and 12 nonusers were studied. Heart rate, blood pressure, and respiratory rate were recorded. Baroreflex sensitivity was estimated by the sequence method, and cardiac autonomic control by analysis of the R-R interval. Pulse wave velocity was measured using a noninvasive automatic device. Mean spontaneous baroreflex sensitivity, baroreflex sensitivity to activation of the baroreceptors, and baroreflex sensitivity to deactivation of the baroreceptors were significantly lower in users than in nonusers. In the spectral analysis of heart rate variability, high frequency activity was lower, while low frequency activity was higher in users than in nonusers. Moreover, the sympathovagal balance was higher in users. Users showed higher pulse wave velocity than nonusers showing arterial stiffness of large vessels. Single linear regression analysis showed significant correlations between mean blood pressure and baroreflex sensitivity and pulse wave velocity. Our results provide evidence for lower baroreflex sensitivity and sympathovagal imbalance in anabolic androgenic steroid users. Moreover, anabolic androgenic steroid users showed arterial stiffness. Together, these alterations might be the mechanisms triggering the increased blood pressure in this population.

Apparatus for and method of operating a cylindrical pulsed induction mass launcher

DOEpatents

Cowan, M. Jr.; Duggin, B.W.; Widner, M.M.

1992-06-30

An electromagnetic cylindrical projectile mass launcher and a method of operation is provided which includes a cylindrical projectile having a conducting armature, a cylindrical barrel in which the armature is received, a plurality of electromagnetic drive coil stages, a plurality of pulse energy sources, and a pulsed power arrangement for generating magnetic pulses forming a pulsed magnetic wave along the length of the launcher barrel. The pulsed magnetic wave provides a propelling force on the projectile along the drive coil. The pulsed magnetic wave of the drive coil stages is advanced along the armature faster than the projectile to thereby generate an induced current wave in the armature. The pulsed generation of the magnetic wave minimizes electromagnetic heating of the projectile and provides for smooth acceleration of the projectile through the barrel of the launcher. 2 figs.

Apparatus for and method of operating a cylindrical pulsed induction mass launcher

DOEpatents

Cowan, Jr., Maynard; Duggin, Billy W.; Widner, Melvin M.

1992-01-01

An electromagnetic cylindrical projectile mass launcher and a method of operation is provided which includes a cylindrical projectile having a conducting armature, a cylindrical barrel in which the armature is received, a plurality of electromagnetic drive coil stages, a plurality of pulse energy sources, and a pulsed power arrangement for generating magnetic pulses forming a pulsed magnetic wave along the length of the launcher barrel. The pulsed magnetic wave provides a propelling force on the projectile along the drive coil. The pulsed magnetic wave of the drive coil stages is advanced along the armature faster than the projectile to thereby generate an induced current wave in the armature. The pulsed generation of the magnetic wave minimizes electromagnetic heating of the projectile and provides for smooth acceleration of the projectile through the barrel of the launcher.

Peripheral vasomotor activity assessment using a continuous wavelet analysis on webcam photoplethysmographic signals.

PubMed

Bousefsaf, F; Maaoui, C; Pruski, A

2016-11-25

Vasoconstriction and vasodilation phenomena reflect the relative changes in the vascular bed. They induce particular modifications in the pulse wave magnitude. Webcams correspond to remote sensors that can be employed to measure the pulse wave in order to compute the pulse frequency. Record and analyze pulse wave signal with a low-cost webcam to extract the amplitude information and assess the vasomotor activity of the participant. Photoplethysmographic signals obtained from a webcam are analyzed through a continuous wavelet transform. The performance of the proposed filtering technique was evaluated using approved contact probes on a set of 12 healthy subjects after they perform a short but intense physical exercise. During the rest period, a cutaneous vasodilation is observable. High degrees of correlation between the webcam and a reference sensor were obtained. Webcams are low-cost and non-contact devices that can be used to reliably estimate both heart rate and peripheral vasomotor activity, notably during physical exertion.

The role of the global phase in the spatio-temporal evolution of strong-coupling Brillouin scattering

NASA Astrophysics Data System (ADS)

Amiranoff, F.; Riconda, C.; Chiaramello, M.; Lancia, L.; Marquès, J. R.; Weber, S.

2018-01-01

The role of the global phase in the spatio-temporal evolution of the 3-wave coupled equations for backscattering is analyzed in the strong-coupling regime of Brillouin scattering. This is of particular interest for controlled backscattering in the case of plasma-based amplification to produce short and intense laser pulses. It is shown that the analysis of the envelope equations of the three waves involved, pump, seed, and ion wave, in terms of phase and amplitude fully describes the coupling dynamics. In particular, it helps understanding the role of the chirp of the laser beams and of the plasma density profile. The results can be used to optimize or quench the coupling mechanism. It is found that the directionality of the energy transfer is imposed by the phase relation at the leading edge of the pulse. This actually ensures continued energy transfer even if the intensity of the seed pulse is already higher than the pump pulse intensity.

Physical exercise, fitness and dietary pattern and their relationship with circadian blood pressure pattern, augmentation index and endothelial dysfunction biological markers: EVIDENT study protocol

PubMed Central

2010-01-01

Background Healthy lifestyles may help to delay arterial aging. The purpose of this study is to analyze the relationship of physical activity and dietary pattern to the circadian pattern of blood pressure, central and peripheral blood pressure, pulse wave velocity, carotid intima-media thickness and biological markers of endothelial dysfunction in active and sedentary individuals without arteriosclerotic disease. Methods/Design Design: A cross-sectional multicenter study with six research groups. Subjects: From subjects of the PEPAF project cohort, in which 1,163 who were sedentary became active, 1,942 were sedentary and 2,346 were active. By stratified random sampling, 1,500 subjects will be included, 250 in each group. Primary measurements: We will evaluate height, weight, abdominal circumference, clinical and ambulatory blood pressure with the Radial Pulse Wave Acquisition Device (BPro), central blood pressure and augmentation index with Pulse Wave Application Software (A-Pulse) and SphymgoCor System Px (Pulse Wave Analysis), pulse wave velocity (PWV) with SphymgoCor System Px (Pulse Wave Velocity), nutritional pattern with a food intake frequency questionnaire, physical activity with the 7-day PAR questionnaire and accelerometer (Actigraph GT3X), physical fitness with the cycle ergometer (PWC-170), carotid intima-media thickness by ultrasound (Micromax), and endothelial dysfunction biological markers (endoglin and osteoprotegerin). Discussion Determining that sustained physical activity and the change from sedentary to active as well as a healthy diet improve circadian pattern, arterial elasticity and carotid intima-media thickness may help to propose lifestyle intervention programs. These interventions could improve the cardiovascular risk profile in some parameters not routinely assessed with traditional risk scales. From the results of this study, interventional approaches could be obtained to delay vascular aging that combine physical exercise and diet. Trial Registration Clinical Trials.gov Identifier: NCT01083082 PMID:20459634

Measuring the Carotid to Femoral Pulse Wave Velocity (Cf-PWV) to Evaluate Arterial Stiffness.

PubMed

Ji, Hongwei; Xiong, Jing; Yu, Shikai; Chi, Chen; Bai, Bin; Teliewubai, Jiadela; Lu, Yuyan; Zhang, Yi; Xu, Yawei

2018-05-03

For the elderly, arterial stiffening is a good marker for aging evaluation and it is recommended that the arterial stiffness be determined noninvasively by the measurement of carotid to femoral pulse wave velocity (cf-PWV) (Class I; Level of Evidence A). In literature, numerous community-based or disease-specific studies have reported that higher cf-PWV is associated with increased cardiovascular risk. Here, we discuss strategies to evaluate arterial stiffness with cf-PWV. Following the well-defined steps detailed here, e.g., proper position operator, distance measurement, and tonometer position, we will obtain a standard cf-PWV value to evaluate arterial stiffness. In this paper, a detailed stepwise method to record a good quality PWV and pulse wave analysis (PWA) using a non-invasive tonometry-based device will be discussed.

Stable cavitation induces increased cytoplasmic calcium in L929 fibroblasts exposed to 1-MHz pulsed ultrasound.

PubMed

Tsukamoto, Akira; Higashiyama, Satoru; Yoshida, Kenji; Watanabe, Yoshiaki; Furukawa, Katsuko S; Ushida, Takashi

2011-12-01

An increase in cytoplasmic calcium (Ca(2+) increase) is a second messenger that is often observed under ultrasound irradiation. We hypothesize that cavitation is a physical mechanism that underlies the increase in Ca(2+) in these experiments. To control the presence of cavitation, the wave type was controlled in a sonication chamber. One wave type largely contained a traveling wave (wave type A) while the other wave type largely contained a standing wave (wave type B). Fast Fourier transform (FFT) analysis of a sound field produced by the wave types ascertained that stable cavitation was present only under wave type A ultrasound irradiation. Under the two controlled wave types, the increase in Ca(2+) in L929 fibroblasts was observed with fluorescence imaging. Under wave type A ultrasound irradiation, an increase in Ca(2+) was observed; however, no increase in Ca(2+) was observed under wave type B ultrasound irradiation. We conclude that stable cavitation is involved in the increase of Ca(2+) in cells subjected to pulsed ultrasound. Copyright © 2011 Elsevier B.V. All rights reserved.

Computational and Experimental Analysis of Mach 5 Air Flow over a Cylinder with a Nanosecond Pulse Discharge

DTIC Science & Technology

2012-01-01

wind tunnel t = 4:1 s after a discharge event. The compression wave pushes the bow - shock outward, as seen in the red region. Consistent with the two... wind tunnel , which was able to computationally replicate the bow - shock structure seen in the schlieren photography, predict the width of the tunnel’s...from the pulse source. As the shock wave travels upstream, it interacts with the standing bow - shock and momentarily increases the bow - shock

Analysis of D’Alembert Unfolding Technique for Hopkinson Bar Gage Records

DTIC Science & Technology

1992-06-01

MIPH No. 90652 The lfnorcqs in ttn:s ýprrt 7-n Deoarirne~nt o ý te Ip~ A~ r chn ;r vF’ pl J<P D lne! I~rozgj~lj~ The ccnitpnts of trhi-, repoit w;’ rf...0 -I0u’ -4 S.2 ,i i I II III i 00 0 04 ( d )3dflSS8dd 4 pulse is applied. This pressure pulse propagates down...GAGE WAVE TRAVEL WHEN STRESS WAVE IS AT WAV TAVE POSITIONS A, B, C, AND D Figure 2. Description of wave propagation and strain gage output in a bar

Two-dimensional dissipative rogue waves due to time-delayed feedback in cavity nonlinear optics.

PubMed

Tlidi, Mustapha; Panajotov, Krassimir

2017-01-01

We demonstrate a way to generate two-dimensional rogue waves in two types of broad area nonlinear optical systems subject to time-delayed feedback: in the generic Lugiato-Lefever model and in the model of a broad-area surface-emitting laser with saturable absorber. The delayed feedback is found to induce a spontaneous formation of rogue waves. In the absence of delayed feedback, spatial pulses are stationary. The rogue waves are exited and controlled by the delay feedback. We characterize their formation by computing the probability distribution of the pulse height. The long-tailed statistical contribution, which is often considered as a signature of the presence of rogue waves, appears for sufficiently strong feedback. The generality of our analysis suggests that the feedback induced instability leading to the spontaneous formation of two-dimensional rogue waves is a universal phenomenon.

Dynamics of wave packets in two-dimensional random systems with anisotropic disorder.

PubMed

Samelsohn, Gregory; Gruzdev, Eugene

2008-09-01

A theoretical model is proposed to describe narrowband pulse dynamics in two-dimensional systems with arbitrary correlated disorder. In anisotropic systems with elongated cigarlike inhomogeneities, fast propagation is predicted in the direction across the structure where the wave is exponentially localized and tunneling of evanescent modes plays a dominant role in typical realizations. Along the structure, where the wave is channeled as in a waveguide, the motion of the wave energy is relatively slow. Numerical simulations performed for ultra-wide-band pulses show that even at the initial stage of wave evolution, the radiation diffuses predominantly in the direction along the major axis of the correlation ellipse. Spectral analysis of the results relates the long tail of the wave observed in the transverse direction to a number of frequency domain "lucky shots" associated with the long-living resonant modes localized inside the sample.

Dynamics of wave packets in two-dimensional random systems with anisotropic disorder

NASA Astrophysics Data System (ADS)

Samelsohn, Gregory; Gruzdev, Eugene

2008-09-01

A theoretical model is proposed to describe narrowband pulse dynamics in two-dimensional systems with arbitrary correlated disorder. In anisotropic systems with elongated cigarlike inhomogeneities, fast propagation is predicted in the direction across the structure where the wave is exponentially localized and tunneling of evanescent modes plays a dominant role in typical realizations. Along the structure, where the wave is channeled as in a waveguide, the motion of the wave energy is relatively slow. Numerical simulations performed for ultra-wide-band pulses show that even at the initial stage of wave evolution, the radiation diffuses predominantly in the direction along the major axis of the correlation ellipse. Spectral analysis of the results relates the long tail of the wave observed in the transverse direction to a number of frequency domain “lucky shots” associated with the long-living resonant modes localized inside the sample.

Optoacoustic theranostics

NASA Astrophysics Data System (ADS)

Petrov, Irene Y.; Micci, Maria-Adelaide; Prough, Donald S.; Petrov, Yuriy; Guptarak, Jutatip; Grant, Auston C.; Parsley, Margaret A.; Bolding, Ian J.; Esenaliev, Rinat O.

2018-03-01

Optoacoustic diagnostics is based on detection and analysis of optoacoustic waves induced in tissues. It may find a number of important clinical applications in large populations of patients such as diagnostics of cerebral hypoxia, circulatory shock, etc. Recently, we proposed Nano-Pulse Laser Therapy (NPLT) which utilizes short optical pulses (typically, shorter than hundreds of nanoseconds) to generate optoacoustic waves in tissues upon stress-confined irradiation. It is well known that continuous wave low-level near-infrared light can be used for therapy/photobiomodulation to stimulate, repair, regenerate, and protect injured tissue. In the past few years, new works emerged on therapeutic effects of low-intensity ultrasound waves. The NPLT consists of irradiating tissue by both lowlevel light and optoacoustic waves/ultrasound that combines merits of low-level light and ultrasound therapies. In this work we propose optoacoustic theranostics that can be used for diagnostics, optoacoustic therapy/NPLT, and monitoring of therapeutic response during and after therapy. We developed and built pulsed, tunable, near infrared (680-1064 nm), fiber-coupled systems for optoacoustic theranostics and tested them in rats with traumatic brain injury (TBI). Low energy pulses were used for optoacoustic monitoring of cerebral blood oxygenation, while higher energy pulses were used for the NPLT. Our studies show that TBI results in cerebral hypoxia, while a 5-minute transcranial application of NPLT significantly reduces negative effects of TBI as assessed by vestibulomotor, cognitive, and immunofluorescence tests. The obtained results suggest that the optoacoustic theranostics may be used for diagnostics and management of TBI and other disorders.

Factors associated with arterial stiffness in children aged 9-10 years

PubMed Central

Batista, Milena Santos; Mill, José Geraldo; Pereira, Taisa Sabrina Silva; Fernandes, Carolina Dadalto Rocha; Molina, Maria del Carmen Bisi

2015-01-01

OBJECTIVE To analyze the factors associated with stiffness of the great arteries in prepubertal children. METHODS This study with convenience sample of 231 schoolchildren aged 9-10 years enrolled in public and private schools in Vitória, ES, Southeastern Brazil, in 2010-2011. Anthropometric and hemodynamic data, blood pressure, and pulse wave velocity in the carotid-femoral segment were obtained. Data on current and previous health conditions were obtained by questionnaire and notes on the child’s health card. Multiple linear regression was applied to identify the partial and total contribution of the factors in determining the pulse wave velocity values. RESULTS Among the students, 50.2% were female and 55.4% were 10 years old. Among those classified in the last tertile of pulse wave velocity, 60.0% were overweight, with higher mean blood pressure, waist circumference, and waist-to-height ratio. Birth weight was not associated with pulse wave velocity. After multiple linear regression analysis, body mass index (BMI) and diastolic blood pressure remained in the model. CONCLUSIONS BMI was the most important factor in determining arterial stiffness in children aged 9-10 years. PMID:25902563

EVOLUTION OF FAST MAGNETOACOUSTIC PULSES IN RANDOMLY STRUCTURED CORONAL PLASMAS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yuan, D.; Li, B.; Pascoe, D. J.

2015-02-01

We investigate the evolution of fast magnetoacoustic pulses in randomly structured plasmas, in the context of large-scale propagating waves in the solar atmosphere. We perform one-dimensional numerical simulations of fast wave pulses propagating perpendicular to a constant magnetic field in a low-β plasma with a random density profile across the field. Both linear and nonlinear regimes are considered. We study how the evolution of the pulse amplitude and width depends on their initial values and the parameters of the random structuring. Acting as a dispersive medium, a randomly structured plasma causes amplitude attenuation and width broadening of the fast wavemore » pulses. After the passage of the main pulse, secondary propagating and standing fast waves appear. Width evolution of both linear and nonlinear pulses can be well approximated by linear functions; however, narrow pulses may have zero or negative broadening. This arises because narrow pulses are prone to splitting, while broad pulses usually deviate less from their initial Gaussian shape and form ripple structures on top of the main pulse. Linear pulses decay at an almost constant rate, while nonlinear pulses decay exponentially. A pulse interacts most efficiently with a random medium with a correlation length of about half of the initial pulse width. This detailed model of fast wave pulses propagating in highly structured media substantiates the interpretation of EIT waves as fast magnetoacoustic waves. Evolution of a fast pulse provides us with a novel method to diagnose the sub-resolution filamentation of the solar atmosphere.« less

Surface-Wave Pulse Routing around Sharp Right Angles

NASA Astrophysics Data System (ADS)

Gao, Z.; Xu, H.; Gao, F.; Zhang, Y.; Luo, Y.; Zhang, B.

2018-04-01

Surface-plasmon polaritons (SPPs), or localized electromagnetic surface waves propagating on a metal-dielectric interface, are deemed promising information carriers for future subwavelength terahertz and optical photonic circuitry. However, surface waves fundamentally suffer from scattering loss when encountering sharp corners in routing and interconnection of photonic signals. Previous approaches enabling scattering-free surface-wave guidance around sharp corners are limited to either volumetric waveguide environments or extremely narrow bandwidth, being unable to guide a surface-wave pulse (SPP wave packet) on an on-chip platform. Here, in a surface-wave band-gap crystal implemented on a single metal surface, we demonstrate in time-domain routing a surface-wave pulse around multiple sharp right angles without perceptible scattering. Our work not only offers a solution to on-chip surface-wave pulse routing along an arbitrary path, but it also provides spatiotemporal information on the interplay between surface-wave pulses and sharp corners, both of which are desirable in developing high-performance large-scale integrated photonic circuits.

Headspace Analysis of Volatile Compounds Using Segemented Chirped-Pulse Fourier Transform Mm-Wave Spectroscopy

NASA Astrophysics Data System (ADS)

Harris, Brent; Steber, Amanda; Pate, Brooks

2014-06-01

A chirped-pulse Fourier transform mm-wave spectrometer has been tested in analytical chemistry applications of headspace analysis of volatile species. A solid-state mm-wave light source (260-290 GHz) provides 30-50 mW of power. This power is sufficient to achieve optimal excitation of individual transitions of molecules with dipole moments larger than about 0.1 D. The chirped-pulse spectrometer has near 100% measurement duty cycle using a high-speed digitizer (4 GS/s) with signal accumulation in an FPGA. The combination of the ability to perform optimal pulse excitation and near 100% measurement duty cycle gives a spectrometer that is fully optimized for trace detection. The performance of the instrument is tested using an EPA sample (EPA VOC Mix 6 - Supelco) that contains a set of molecules that are fast eluting on gas chromatographs and, as a result, present analysis challenges to mass spectrometry. The ability to directly analyze the VOC mixture is tested by acquiring the full bandwidth (260-290 GHz) spectrum in a "high dynamic range" measurement mode that minimizes spurious spectrometer responses. The high-resolution of molecular rotational spectroscopy makes it easy to analyze this mixture without the need for chemical separation. The sensitivity of the instrument for individual molecule detection, where a single transition is polarized by the excitation pulse, is also tested. Detection limits in water will be reported. In the case of chloromethane, the detection limit (0.1 microgram/L), matches the sensitivity reported in the EPA measurement protocol (EPA Method 524) for GC/MS.

Wave processes in the human cardiovascular system: The measuring complex, computing models, and diagnostic analysis

NASA Astrophysics Data System (ADS)

Ganiev, R. F.; Reviznikov, D. L.; Rogoza, A. N.; Slastushenskiy, Yu. V.; Ukrainskiy, L. E.

2017-03-01

A description of a complex approach to investigation of nonlinear wave processes in the human cardiovascular system based on a combination of high-precision methods of measuring a pulse wave, mathematical methods of processing the empirical data, and methods of direct numerical modeling of hemodynamic processes in an arterial tree is given.

Efficiency assessment of shock wave therapy in patients with pelvic pain employing harmonic analysis of penile bioimpedance.

PubMed

Khodyreva, L A; Dudareva, A A; Mudraya, I S; Markosyan, T G; Revenko, S V; Kumachev, K V; Logvinov, L A

2013-06-01

In searching for novel objective methods to diagnosticate pelvic pain and assess efficiency of analgesic therapy, 37 male patients were examined prior to and after the course of extracorporeal shock wave therapy (5-10 sessions) with the waves directed to projections of prostate and/or crura and shaft of the penis. The repetition rate of mechanical pulses was 3-5 Hz. The range of energy pulse density was 0.09-0.45 mJ/mm(2). The overall number of pulses in a session was 1500-3000 in any treated zone with total energy smaller than 60 J. The applicator was relocated every other series of 300-500 pulses. Effect of the shock wave therapy was assessed according to subjective symptomatic scales: International Prostate Symptom Score, International Index of Erectile Function, Quality of Life, and nociceptive Visual Analog Scale. The objective assessment of shock wave therapy was performed with harmonic analysis of penile bioimpedance variability, which quantitatively evaluated the low-frequency rhythmic and asynchronous activities at rest as well as the total pulsatile activity of the penis. The magnitude of spectrum components of bioimpedance variations was assessed with a novel parameter, the effective impedance. The spectral parameters were measured in 16 patients prior to and after the treatment course. The corresponding control values were measured in the group of healthy patients. Prior to the shock wave therapy course, all spectrum parameters of penile bioimpedance significantly differed from the control (p<0.05). After this course, low-frequency rhythmic and the total pulsatile activity decreased to normal, while asynchronous activity remained significantly different from the normal. The novel objective physiological criteria of pelvic pain diagnostics and efficiency of its treatment reflecting the regional features of circulation and neural activity corresponded to the clinical symptom scaling prior to and after the shock wave course, and on the whole, these criteria corroborated improvement of the patient state after this therapy.

Analysis of an axial compressor blade vibration based on wave reflection theory

NASA Technical Reports Server (NTRS)

Owczarek, J. A.

1983-01-01

The paper describes application of the theory of wave reflection in turbomachines to rotor blade vibrations measured in an axial compressor stage. The blade vibrations analyzed could not be predicted using various flutter prediction techniques. The wave reflection theory, first advanced in 1966, is expanded, and more general equations for the rotor blade excitation frequencies are derived. The results of the analysis indicate that all examined rotor blade vibrations can be explained by forced excitations caused by reflecting waves (pressure pulses). Wave reflections between the rotor blades and both the upstream and downstream stator vanes had to be considered.

Multiphase Oscillator Using Traveling Pulses Developed in a System of Transmission Lines with Regularly Spaced Resonant-tunneling Diodes

NASA Astrophysics Data System (ADS)

Narahara, Koichi

2017-06-01

A scheme is proposed for generating multiphase oscillatory signals in millimeter-wave frequencies based on the dynamics of a traveling pulse developed in a closed transmission line periodically loaded with resonant-tunneling diodes (RTDs) that is coupled with several straight RTD lines. When supplied with an appropriate voltage at the end of an RTD line, a pulse edge is shown to exhibit a spatially extended limit-cycle oscillation on the line. We consider the case where several RTD lines are connected halfway to a closed one at even intervals. In this case, the oscillatory edge developed in each straight RTD line is mutually synchronized such that a pulse-shaped rotary traveling wave develops on the closed RTD line. The oscillating edge on each straight line is also synchronized with the traveling pulse on the closed line, such that the leading edge of the traveling pulse on the closed line and the forward edge on the straight line pass the cross point simultaneously. As a result, when N L straight lines are connected to the closed line, the phase difference between two adjacent oscillatory edges becomes 2 π/ N L . On the other hand, the trailing edge of the traveling pulse at the cross point breaks the voltage wave on the straight line into two pieces, one of which travels forward to form a solitary wave and the other of which travels backward to reach the input end, where it is reflected and starts to travel forward and this forward moving edge is supposed to be synchronized with the leading edge of the traveling pulse. It means that a back-and-forth edge and a forward-moving solitary wave develop periodically on each straight line. Because the time required for the traveling pulse to go around the closed line must be coincident with the period of the edge oscillation on each straight line, a unique traveling pulse cannot synchronize with each oscillating edge when the cell size of the closed line becomes large, resulting in the development of multiple traveling pulses on the closed line. In this paper, the design criteria are discussed concerning the connecting point between the straight and closed lines, the number of straight lines, and the size of the closed line. In addition, we describe several measurement results that validate the essential properties of the traveling pulse and then show several results of full-wave analysis of a monolithically integrated RTD line.

Optimisation of parameters of Raman laser pulse compression in a plasma for its implementation using the PEARL laser facility (IAP RAS)

NASA Astrophysics Data System (ADS)

Balakin, A. A.; Levin, D. S.; Skobelev, S. A.

2018-04-01

We consider Raman compression of laser pulses in a plasma under the conditions of an experiment planned at the Institute of Applied Physics of the Russian Academy of Sciences on the PEARL laser facility. The analysis is based on the equations describing, among other things, the effect of plasma dispersion and relativistic nonlinearity, as well as the dynamics of the field near the plasma wave breaking threshold. It is shown that the main limiting factors are excessive frequency modulation of the pump pulse and a too low plasma density in which the plasma wave breaking can occur. To reduce the negative influence of these effects, we suggest using an intense and short (on the order of the plasma period) seed laser pulse. Numerical simulation shows the possibility of a hundredfold increase in the intensity of the compressed pulse in comparison with the intensity of the pump pulse at a length of uniform plasma of 2 cm.

Non-filamentated ultra-intense and ultra-short pulse fronts in three-dimensional Raman seed amplification

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lehmann, G.; Spatschek, K. H.

Ultra-intense and ultra-short laser pulses may be generated up to the exawatt-zetawatt regime due to parametric processes in plasmas. The minimization of unwanted plasma processes leads to operational limits which are discussed here with respect to filamentation. Transverse filamentation, which originally was derived for plane waves, is being investigated for seed pulse propagation in the so called π-pulse limit. A three-dimensional (3D) three-wave-interaction model is the basis of the present investigation. To demonstrate the applicability of the three-wave-interaction model, the 1D pulse forms are compared with those obtained from 1D particle in cell and Vlasov simulations. Although wave-breaking may occur,more » the kinetic simulations show that the leading pumped pulse develops a form similar to that obtained from the three-wave-interaction model. In the main part, 2D and 3D filamentation processes of (localized) pulses are investigated with the three-wave-interaction model. It is shown that the leading pulse front can stay filamentation-free, whereas the rear parts show transverse modulations.« less

Arterial Wave Reflection and Aortic Valve Calcification in an Elderly Community-Based Cohort

PubMed Central

Sera, Fusako; Russo, Cesare; Iwata, Shinichi; Jin, Zhezhen; Rundek, Tatjana; Elkind, Mitchell S.V.; Homma, Shunichi; Sacco, Ralph L.; Di Tullio, Marco R.

2015-01-01

Background Aortic valve calcification (AVC) without stenosis is common in the elderly, is associated with cardiovascular morbidity and mortality, and may progress to aortic valve stenosis. Arterial stiffness and pulse wave reflection are important components of proximal aortic hemodynamics, but their relationship with AVC is not established. Methods To investigate the relationship of arterial wave reflection and stiffness with AVC, pulse wave analysis and AVC evaluation by echocardiography were performed in 867 participants from the Cardiovascular Abnormalities and Brain Lesions (CABL) study. Participants were divided into 4 categories based on the severity and extent of AVC: 1) none or mild focal AVC; 2) mild diffuse AVC; 3) moderate-severe focal AVC; and 4) moderate-severe diffuse AVC. Central blood pressures and pulse pressure, total arterial compliance, augmentation index, and time to wave reflection were assessed using applanation tonometry. Results Indicators of arterial stiffness and wave reflection were significantly associated with AVC severity, except for central systolic and diastolic pressures and time to reflection. After adjustment for pertinent covariates (age, sex, race/ethnicity, and eGFR), only augmentation pressure (P = .02) and augmentation index (P = .002) were associated with the severity of AVC. Multivariable logistic regression analysis revealed that augmentation pressure (odds ratio per mmHg = 1.14; 95% confidence interval, 1.02–1.27; P = .02) and augmentation index (odds ratio per percentage point = 1.07; 95% confidence interval, 1.01–1.13; P = .02) were associated with an increase risk of moderate-severe diffuse AVC, even when central blood pressure value was included in the same model. Conclusions Arterial wave reflection is associated with AVC severity, independent of blood pressure values. Increased contribution of wave reflection to central blood pressure could be involved in the process leading to AVC. PMID:25600036

Bubble-based acoustic radiation force using chirp insonation to reduce standing wave effects.

PubMed

Erpelding, Todd N; Hollman, Kyle W; O'Donnell, Matthew

2007-02-01

Bubble-based acoustic radiation force can measure local viscoelastic properties of tissue. High intensity acoustic waves applied to laser-generated bubbles induce displacements inversely proportional to local Young's modulus. In certain instances, long pulse durations are desirable but are susceptible to standing wave artifacts, which corrupt displacement measurements. Chirp pulse acoustic radiation force was investigated as a method to reduce standing wave artifacts. Chirp pulses with linear frequency sweep magnitudes of 100, 200 and 300 kHz centered around 1.5 MHz were applied to glass beads within gelatin phantoms and laser-generated bubbles within porcine lenses. The ultrasound transducer was translated axially to vary standing wave conditions, while comparing displacements using chirp pulses and 1.5 MHz tone burst pulses of the same duration and peak rarefactional pressure. Results demonstrated significant reduction in standing wave effects using chirp pulses, with displacement proportional to acoustic intensity and bubble size.

Bubble-Based Acoustic Radiation Force Using Chirp Insonation to Reduce Standing Wave Effects

PubMed Central

Erpelding, Todd N.; Hollman, Kyle W.; O’Donnell, Matthew

2007-01-01

Bubble-based acoustic radiation force can measure local viscoelastic properties of tissue. High intensity acoustic waves applied to laser-generated bubbles induce displacements inversely proportional to local Young’s modulus. In certain instances, long pulse durations are desirable but are susceptible to standing wave artifacts, which corrupt displacement measurements. Chirp pulse acoustic radiation force was investigated as a method to reduce standing wave artifacts. Chirp pulses with linear frequency sweep magnitudes of 100, 200, and 300 kHz centered around 1.5 MHz were applied to glass beads within gelatin phantoms and laser-generated bubbles within porcine lenses. The ultrasound transducer was translated axially to vary standing wave conditions, while comparing displacements using chirp pulses and 1.5 MHz tone burst pulses of the same duration and peak rarefactional pressure. Results demonstrated significant reduction in standing wave effects using chirp pulses, with displacement proportional to acoustic intensity and bubble size. PMID:17306697

Max dD/Dt: A Novel Parameter to Assess Fetal Cardiac Contractility and a Substitute for Max dP/Dt.

PubMed

Fujita, Yasuyuki; Kiyokoba, Ryo; Yumoto, Yasuo; Kato, Kiyoko

2018-07-01

Aortic pulse waveforms are composed of a forward wave from the heart and a reflection wave from the periphery. We focused on this forward wave and suggested a new parameter, the maximum slope of aortic pulse waveforms (max dD/dt), for fetal cardiac contractility. Max dD/dt was calculated from fetal aortic pulse waveforms recorded with an echo-tracking system. A normal range of max dD/dt was constructed in 105 healthy fetuses using linear regression analysis. Twenty-two fetuses with suspected fetal cardiac dysfunction were divided into normal and decreased max dD/dt groups, and their clinical parameters were compared. Max dD/dt of aortic pulse waveforms increased linearly with advancing gestational age (r = 0.93). The decreased max dD/dt was associated with abnormal cardiotocography findings and short- and long-term prognosis. In conclusion, max dD/dt calculated from the aortic pulse waveforms in fetuses can substitute for max dP/dt, an index of cardiac contractility in adults. Copyright © 2018 World Federation for Ultrasound in Medicine and Biology. Published by Elsevier Inc. All rights reserved.

Real-time Analysis of Global Waves Accompanying Coronal Mass Ejections

DTIC Science & Technology

2016-09-01

Moreton–Ramsey waves were not propagating in the chromosphere, but were instead the footprint of a global wave pulse moving through the solar corona above... corona and in 1997 the first observations were made of a global wave propagating through the low solar corona (see bottom row of Figure 1 and the...Procedures While there are similarities in the behaviour and morphology of both Moreton–Ramsey waves and “EIT waves”, the low solar corona and solar

Velocity measurement using frequency domain interferometer and chirped pulse laser

NASA Astrophysics Data System (ADS)

Ishii, K.; Nishimura, Y.; Mori, Y.; Hanayama, R.; Kitagawa, Y.; Sekine, T.; Sato, N.; Kurita, T.; Kawashima, T.; Sunahara, A.; Sentoku, Y.; Miura, E.; Iwamoto, A.; Sakagami, H.

2017-02-01

An ultra-intense short pulse laser induces a shock wave in material. The pressure of shock compression is stronger than a few tens GPa. To characterize shock waves, time-resolved velocity measurement in nano- or pico-second time scale is needed. Frequency domain interferometer and chirped pulse laser provide single-shot time-resolved measurement. We have developed a laser-driven shock compression system and frequency domain interferometer with CPA laser. In this paper, we show the principle of velocity measurement using a frequency domain interferometer and a chirped pulse laser. Next, we numerically calculated spectral interferograms and show the time-resolved velocity measurement can be done from the phase analysis of spectral interferograms. Moreover we conduct the laser driven shock generation and shock velocity measurement. From the spectral fringes, we analyze the velocities of the sample and shockwaves.

Holographic measurement of wave propagation in axi-symmetric shells

NASA Technical Reports Server (NTRS)

Evensen, D. A.; Aprahamian, R.; Jacoby, J. L.

1972-01-01

The report deals with the use of pulsed, double-exposure holographic interferometry to record the propagation of transverse waves in thin-walled axi-symmetric shells. The report is subdivided into sections dealing with: (1) wave propagation in circular cylindrical shells, (2) wave propagation past cut-outs and stiffeners, and (3) wave propagation in conical shells. Several interferograms are presented herein which show the waves reflecting from the shell boundaries, from cut-outs, and from stiffening rings. The initial response of the shell was nearly axi-symmetric in all cases, but nonsymmetric modes soon appeared in the radial response. This result suggests that the axi-symmetric response of the shell may be dynamically unstable, and thus may preferentially excite certain circumferential harmonics through parametric excitation. Attempts were made throughout to correlate the experimental data with analysis. For the most part, good agreement between theory and experiment was obtained. Occasional differences were attributed primarily to simplifying assumptions used in the analysis. From the standpoint of engineering applications, it is clear that pulsed laser holography can be used to obtain quantitative engineering data. Areas of dynamic stress concentration, stress concentration factors, local anomalies, etc., can be readily determined by holography.

Octave-spanning supercontinuum generation in a silicon-rich nitride waveguide.

PubMed

Liu, Xing; Pu, Minhao; Zhou, Binbin; Krückel, Clemens J; Fülöp, Attila; Torres-Company, Victor; Bache, Morten

2016-06-15

We experimentally show octave-spanning supercontinuum generation in a nonstoichiometric silicon-rich nitride waveguide when pumped by femtosecond pulses from an erbium fiber laser. The pulse energy and bandwidth are comparable to results achieved in stoichiometric silicon nitride waveguides, but our material platform is simpler to manufacture. We also observe wave-breaking supercontinuum generation by using orthogonal pumping in the same waveguide. Additional analysis reveals that the waveguide height is a powerful tuning parameter for generating mid-infrared dispersive waves while keeping the pump in the telecom band.

Development of integrated photoplethysmographic recording circuit for trans-nail pulse-wave monitoring system

NASA Astrophysics Data System (ADS)

Qian, Zhengyang; Takezawa, Yoshiki; Shimokawa, Kenji; Kino, Hisashi; Fukushima, Takafumi; Kiyoyama, Koji; Tanaka, Tetsu

2018-04-01

Health monitoring and self-management have become increasingly more important because of health awareness improvement, the aging of population, and other reasons. In general, pulse waves are among the most useful physiological signals that can be used to calculate several parameters such as heart rate and blood pressure for health monitoring and self-management. To realize an automatic and real-time pulse-wave monitoring system that can be used in daily life, we have proposed a trans-nail pulse-wave monitoring system that was placed on the fingernail to detect photoplethysmographic (PPG) signals as pulse waves. In this study, we designed a PPG recording circuit that was composed of a 600 × 600 µm2 photodiode (PD), an LED driver with pulse wave modulation (PWM) and a low-frequency ring oscillator (RING), and a PPG signal readout circuit. The proposed circuit had a very small area of 2.2 × 1.1 mm2 designed with 0.18 µm CMOS technology. The proposed circuit was used to detect pulse waves on the human fingernail in both the reflection and transmission modes. Electrical characteristics of the prototype system were evaluated precisely and PPG waveforms were obtained successfully.

Shock transmission in coupled beams and rib stiffened structures

NASA Technical Reports Server (NTRS)

Pope, L. D.; Manning, J. E.; Scharton, T. D.

1971-01-01

Shock transmission in a simple coupled beam structure and in a ring-stringer stiffened cylinder is investigated experimentally and analytically using wave transmission and statistical energy analysis concepts. The use of the response spectrum to characterize the excitation provided to a simple beam by a force pulse is studied. Analysis of the transmission of a dilatation wave in a periodically stiffened plate indicates that the stiffeners are fairly transparent to the wave, but some of the dilatational energy is scattered into bending at each support.

Studies of the Propagation of Elastic Waves in Fluids and Solids.

DTIC Science & Technology

1983-12-15

and scattering of ultrasound ; studies of the generation, propagation, and detection of acoustic transients, including laser induced pressure pulses... ultrasound in water and other liquids. The wide band acoustic pulses used to calibrate the various hydrophones were produced by driving thick PZT...Analysis of Pulsed Ultrasonic Fields by PVDF Spot-Poled Membrane Hydrophones, G. R. Harris, E. F. Carome and H. D. Dardy, IEEE Trans. Sonics Ultrason., SU

High-Intensity Interval Cycling Exercise on Wave Reflection and Pulse Wave Velocity.

PubMed

Kingsley, J Derek; Tai, Yu Lun; Vaughan, Jeremiah A; Mayo, Xián

2017-05-01

Kingsley, JD, Tai, YL, Vaughan, J, and Mayo, X. High-intensity interval cycling exercise on wave reflection and pulse wave velocity. J Strength Cond Res 31(5): 1313-1320, 2017-The purpose of this study was to assess the effects of high-intensity exercise on wave reflection and aortic stiffness. Nine young, healthy men (mean ± SD: age: 22 ± 2 years) participated in the study. The high-intensity interval cycling exercise consisted of 3 sets of Wingate Anaerobic Tests (WATs) with 7.5% of bodyweight as resistance and 2 minutes of rest between each set. Measurements were taken at rest and 1 minute after completion of the WATs. Brachial and aortic blood pressures, as well as wave reflection characteristics, were measured through pulse wave analysis. Aortic stiffness was assessed through carotid-femoral pulse wave velocity (cfPWV). A repeated-measures analysis of variance was used to investigate the effects of the WATs on blood pressure and vascular function across time. There was no change in brachial or aortic systolic pressure from rest to recovery. There was a significant (p ≤ 0.05) decrease in brachial diastolic pressure (rest: 73 ± 6 mm Hg; recovery: 67 ± 9 mm Hg) and aortic diastolic pressure (rest: 75 ± 6 mm Hg; recovery: 70 ± 9 mm Hg) from rest to recovery. In addition, there was no significant change in the augmentation index (rest: 111.4 ± 6.5%; recovery: 109.8 ± 5.8%, p = 0.65) from rest to recovery. However, there was a significant (p ≤ 0.05) increase in the augmentation index normalized at 75 b·min (rest: 3.29 ± 9.82; recovery 21.21 ± 10.87) during recovery compared with rest. There was no change in cfPWV (rest: 5.3 ± 0.8 m·s; recovery: 5.7 ± 0.5m·s; p = 0.09) in response to the WAT. These data demonstrate that high-intensity interval cycling exercise with short rest periods has a nonsignificant effect on vascular function.

A Two-Color Fourier Transform Mm-Wave Spectrometer for Gas Analysis Operating from 260-295 GHZ

NASA Astrophysics Data System (ADS)

Steber, Amanda L.; Harris, Brent J.; Lehmann, Kevin K.; Pate, Brooks H.

2013-06-01

We have designed a two-color mm-wave spectrometer for Fourier transform mm-wave spectroscopy that uses consumer level components for the tunable synthesizers, digital control of the pulse modulators, and digitization of the coherent free induction decay (FID). The excitation pulses are generated using an x24 active multiplier chain (AMC) that produces a peak power of 30 mW. The microwave input to the AMC is generated in a frequency up conversion circuit that accepts a microwave input frequency from about 2-4 GHz. This circuit also generates the input to the mm-wave subhamonic mixer that creates the local oscillator from a separate 2-4 GHz microwave input. Excitation pulses at two independently tunable frequencies are generated using a dual-channel source based on a low-cost, wideband synthesizer integrated circuit (Valon Technology Model 5008). The outputs of the synthesizer are pulse modulated using a PIN diode switch that is driven using the arbitrary waveform generator (AWG) output of a USB-controlled high-speed digitizer / arbitrary waveform generator combination unit (Tie Pie HS-5 530 XM). The two pulses are combined using a Wilkinson power divider before input to the up conversion circuit. The FID frequency is down converted in a two-stage mixing process to 65 MHz. The two LO frequencies used in the receiver are provided by a second Valon 5008. The FID is digitized at 200 MSamples/s using the 12-bit Tie Pie digitizer. The digital oscilloscope (and its AWG channel) and the two synthesizers use a 10 MHz reference signal from a Rubidium clock to permit time-domain signal averaging. A key feature of the digital oscilloscope is its deep memory of 32 Mpts (complemented by the 64 Mpt memory in the 240 MS/s AWG). This makes it possible to perform several one- and two-color coherent measurements, including pulse echoes and double-resonance spectroscopy, in a single "readout" experiment to speed the analysis of mm-wave rotational spectra. The spectrometer sensitivity and frequency accuracy are illustrated by high-speed measurements of OCS rotational transitions for low-abundance isotopes. Examples of pulse echo measurements to determine the collisional relaxation rate and two-color double-resonance measurements to confirm the presence of a molecular species will be illustrated using OCS as the room-temperature gas sample.

Models of brachial to finger pulse wave distortion and pressure decrement.

PubMed

Gizdulich, P; Prentza, A; Wesseling, K H

1997-03-01

To model the pulse wave distortion and pressure decrement occurring between brachial and finger arteries. Distortion reversion and decrement correction were also our aims. Brachial artery pressure was recorded intra-arterially and finger pressure was recorded non-invasively by the Finapres technique in 53 adult human subjects. Mean pressure was subtracted from each pressure waveform and Fourier analysis applied to the pulsations. A distortion model was estimated for each subject and averaged over the group. The average inverse model was applied to the full finger pressure waveform. The pressure decrement was modelled by multiple regression on finger systolic and diastolic levels. Waveform distortion could be described by a general, frequency dependent model having a resonance at 7.3 Hz. The general inverse model has an anti-resonance at this frequency. It converts finger to brachial pulsations thereby reducing average waveform distortion from 9.7 (s.d. 3.2) mmHg per sample for the finger pulse to 3.7 (1.7) mmHg for the converted pulse. Systolic and diastolic level differences between finger and brachial arterial pressures changed from -4 (15) and -8 (11) to +8 (14) and +8 (12) mmHg, respectively, after inverse modelling, with pulse pressures correct on average. The pressure decrement model reduced both the mean and the standard deviation of systolic and diastolic level differences to 0 (13) and 0 (8) mmHg. Diastolic differences were thus reduced most. Brachial to finger pulse wave distortion due to wave reflection in arteries is almost identical in all subjects and can be modelled by a single resonance. The pressure decrement due to flow in arteries is greatest for high pulse pressures superimposed on low means.

Spatial transport of electron quantum states with strong attosecond pulses

NASA Astrophysics Data System (ADS)

Chovancova, M.; Agueny, H.; Førre, M.; Kocbach, L.; Hansen, J. P.

2017-11-01

This work follows up the work of Dimitrovsky, Briggs and co-workers on translated electron atomic states by a strong field of an atto-second laser pulse, also described as creation of atoms without a nucleus. Here, we propose a new approach by analyzing the electron states in the Kramers-Henneberger moving frame in the dipole approximation. The wave function follows the displacement vector α (t). This allows arbitrarily shaped pulses, including the model delta-function potentials in the Dimitrovsky and Briggs approach. In the case of final-length single-cycle pulses, we apply both the Kramers-Henneberger moving frame analysis and a full numerical treatment of our 1D model. When the laser pulse frequency exceeds the frequency associated by the energy difference between initial and final states, the entire wavefunction is translated in space nearly without loss of coherence, to a well defined distance from the original position where the ionized core is left behind. This statement is demonstrated on the excited Rydberg states (n = 10, n = 15), where almost no distortion in the transported wave functions has been observed. However, the ground state (n = 1) is visibly distorted during the removal by pulses of reasonable frequencies, as also predicted by Dimitrovsky and Briggs analysis. Our approach allows us to analyze general pulses as well as the model delta-function potentials on the same footing in the Kramers-Henneberger frame.

1.9 μm square-wave passively Q-witched mode-locked fiber laser.

PubMed

Ma, Wanzhuo; Wang, Tianshu; Su, Qingchao; Wang, Furen; Zhang, Jing; Wang, Chengbo; Jiang, Huilin

2018-05-14

We propose and demonstrate the operation of Q-switched mode-locked square-wave pulses in a thulium-holmium co-doped fiber laser. By using a nonlinear amplifying loop mirror, continuous square-wave dissipative soliton resonance pulse is obtained with 4.4 MHz repetition rate. With the increasing pump power, square-wave pulse duration can be broadened from 1.7 ns to 3.2 ns. On such basis Q-switched mode-locked operation is achieved by properly setting the pump power and the polarization controllers. The internal mode-locked pulses in Q-switched envelope still keep square-wave type. The Q-switched repetition rate can be varied from 41.6 kHz to 74 kHz by increasing pump power. The corresponding average single-pulse energy increases from 2.67 nJ to 5.2 nJ. The average peak power is also improved from 0.6 W to 1.1 W when continuous square-wave operation is changed into Q-switched mode-locked operation. It indicates that Q-switched mode-locked operation is an effective method to increase the square-wave pulse energy and peak power.

Design and application of pulse information acquisition and analysis system with dynamic recognition in traditional Chinese medicine.

PubMed

Zhang, Jian; Niu, Xin; Yang, Xue-zhi; Zhu, Qing-wen; Li, Hai-yan; Wang, Xuan; Zhang, Zhi-guo; Sha, Hong

2014-09-01

To design the pulse information which includes the parameter of pulse-position, pulse-number, pulse-shape and pulse-force acquisition and analysis system with function of dynamic recognition, and research the digitalization and visualization of some common cardiovascular mechanism of single pulse. To use some flexible sensors to catch the radial artery pressure pulse wave and utilize the high frequency B mode ultrasound scanning technology to synchronously obtain the information of radial extension and axial movement, by the way of dynamic images, then the gathered information was analyzed and processed together with ECG. Finally, the pulse information acquisition and analysis system was established which has the features of visualization and dynamic recognition, and it was applied to serve for ten healthy adults. The new system overcome the disadvantage of one-dimensional pulse information acquisition and process method which was common used in current research area of pulse diagnosis in traditional Chinese Medicine, initiated a new way of pulse diagnosis which has the new features of dynamic recognition, two-dimensional information acquisition, multiplex signals combination and deep data mining. The newly developed system could translate the pulse signals into digital, visual and measurable motion information of vessel.

Characteristics of the pulse waveform during altered nitric oxide synthesis in the rabbit.

PubMed

Weinberg, P D; Habens, F; Kengatharan, M; Barnes, S E; Matz, J; Anggård, E E; Carrier, M J

2001-06-01

Nitrovasodilators produce characteristic changes in the shape of the peripheral pulse wave. Similar changes might also be caused by alteration of endogenous NO activity, which would allow such activity to be assessed in vivo. We investigated whether manipulation of the NO pathway influences the pulse waveform, and the mechanisms involved. The pulse wave in the ear of normal rabbits was examined by reflectance photoplethysmography before and during infusion of vasoactive agents. Pulse wave velocity was assessed by using an additional sensor on the rear foot. A diastolic peak was observed in the ear pulse; its timing was consistent with it being a reflection of the systolic peak from the lower body. The height of the dicrotic notch marking the start of this diastolic wave was decreased by acetylcholine or an NO donor, and further decreased by a phosphodiesterase type V inhibitor. The acetylcholine-induced decreases were blocked by inhibiting NO synthesis with N(G)-nitro-L-arginine methyl ester (L-NAME) but were unaffected by the inactive enantiomer D-NAME. These data demonstrate that NO influences the height of the notch in the pulse wave. Heart rate and blood pressure were altered during acetylcholine or L-NAME infusion, but there were no changes in pulse wave amplitude or velocity, or in the timing of the diastolic peak or dicrotic notch. The slope of the pulse wave between the systolic peak and notch changed substantially. These effects are most convincingly explained by changes in wave reflection, not only from the lower body but also from more proximal sites.

Characteristics of the pulse waveform during altered nitric oxide synthesis in the rabbit

PubMed Central

Weinberg, P D; Habens, F; Kengatharan, M; Barnes, S E; Matz, J; Änggård, E E; Carrier, M J

2001-01-01

Nitrovasodilators produce characteristic changes in the shape of the peripheral pulse wave. Similar changes might also be caused by alteration of endogenous NO activity, which would allow such activity to be assessed in vivo. We investigated whether manipulation of the NO pathway influences the pulse waveform, and the mechanisms involved. The pulse wave in the ear of normal rabbits was examined by reflectance photoplethysmography before and during infusion of vasoactive agents. Pulse wave velocity was assessed by using an additional sensor on the rear foot. A diastolic peak was observed in the ear pulse; its timing was consistent with it being a reflection of the systolic peak from the lower body. The height of the dicrotic notch marking the start of this diastolic wave was decreased by acetylcholine or an NO donor, and further decreased by a phosphodiesterase type V inhibitor. The acetylcholine-induced decreases were blocked by inhibiting NO synthesis with NG-nitro-L-arginine methyl ester (L-NAME) but were unaffected by the inactive enantiomer D-NAME. These data demonstrate that NO influences the height of the notch in the pulse wave. Heart rate and blood pressure were altered during acetylcholine or L-NAME infusion, but there were no changes in pulse wave amplitude or velocity, or in the timing of the diastolic peak or dicrotic notch. The slope of the pulse wave between the systolic peak and notch changed substantially. These effects are most convincingly explained by changes in wave reflection, not only from the lower body but also from more proximal sites. PMID:11375252

Non-invasive continuous blood pressure measurement based on mean impact value method, BP neural network, and genetic algorithm.

PubMed

Tan, Xia; Ji, Zhong; Zhang, Yadan

2018-04-25

Non-invasive continuous blood pressure monitoring can provide an important reference and guidance for doctors wishing to analyze the physiological and pathological status of patients and to prevent and diagnose cardiovascular diseases in the clinical setting. Therefore, it is very important to explore a more accurate method of non-invasive continuous blood pressure measurement. To address the shortcomings of existing blood pressure measurement models based on pulse wave transit time or pulse wave parameters, a new method of non-invasive continuous blood pressure measurement - the GA-MIV-BP neural network model - is presented. The mean impact value (MIV) method is used to select the factors that greatly influence blood pressure from the extracted pulse wave transit time and pulse wave parameters. These factors are used as inputs, and the actual blood pressure values as outputs, to train the BP neural network model. The individual parameters are then optimized using a genetic algorithm (GA) to establish the GA-MIV-BP neural network model. Bland-Altman consistency analysis indicated that the measured and predicted blood pressure values were consistent and interchangeable. Therefore, this algorithm is of great significance to promote the clinical application of a non-invasive continuous blood pressure monitoring method.

Forward and Backward Pressure Waveform Morphology in Hypertension

PubMed Central

Li, Ye; Gu, Haotian; Fok, Henry; Alastruey, Jordi

2017-01-01

We tested the hypothesis that increased pulse wave reflection and altered backward waveform morphology contribute to increased pulse pressure in subjects with higher pulse pressure compared with lower pulse pressure and to actions of vasoactive drugs to increase pulse pressure. We examined the relationship of backward to forward wave morphology in 158 subjects who were evaluated for hypertension (including some normotensive subjects) divided into 3 groups by central pulse pressure: group 1, 33±6.5 mm Hg; group 2, 45±4.1 mm Hg; and group 3, 64±12.9 mm Hg (means±SD) and in healthy normotensive subjects during administration of inotropic and vasomotor drugs. Aortic pressure and flow in the aortic root were estimated by carotid tonometry and Doppler sonography, respectively. Morphology of the backward wave relative to the forward wave was similar in subjects in the lowest and highest tertiles of pulse pressure. Similar results were seen with the inotropic, vasopressor and vasodilator drugs, dobutamine, norepinephrine, and phentolamine, with the backward wave maintaining a constant ratio to the forward wave. However, nitroglycerin, a drug with a specific action to dilate muscular conduit arteries, reduced the amplitude of the backward wave relative to the forward wave from 0.26±0.018 at baseline to 0.19±0.019 during nitroglycerin 30 μg/min IV (P<0.01). These results are best explained by an approximately constant amount of reflection of the forward wave from the peripheral vasculature. The amount of reflection can be modified by dilation of peripheral muscular conduit arteries but contributes little to increased pulse pressure in hypertension. PMID:27920128

Fourier Transform Ultrasound Spectroscopy for the determination of wave propagation parameters.

PubMed

Pal, Barnana

2017-01-01

The reported results for ultrasonic wave attenuation constant (α) in pure water show noticeable inconsistency in magnitude. A "Propagating-Wave" model analysis of the most popular pulse-echo technique indicates that this is a consequence of the inherent wave propagation characteristics in a bounded medium. In the present work Fourier Transform Ultrasound Spectroscopy (FTUS) is adopted to determine ultrasonic wave propagation parameters, the wave number (k) and attenuation constant (α) at 1MHz frequency in tri-distilled water at room temperature (25°C). Pulse-echo signals obtained under same experimental conditions regarding the exciting input signal and reflecting boundary wall of the water container for various lengths of water columns are captured. The Fast Fourier Transform (FFT) components of the echo signals are taken to compute k, α and r, the reflection constant at the boundary, using Oak Ridge and Oxford method. The results are compared with existing literature values. Copyright © 2016 Elsevier B.V. All rights reserved.

Using high speed smartphone cameras and video analysis techniques to teach mechanical wave physics

NASA Astrophysics Data System (ADS)

Bonato, Jacopo; Gratton, Luigi M.; Onorato, Pasquale; Oss, Stefano

2017-07-01

We propose the use of smartphone-based slow-motion video analysis techniques as a valuable tool for investigating physics concepts ruling mechanical wave propagation. The simple experimental activities presented here, suitable for both high school and undergraduate students, allows one to measure, in a simple yet rigorous way, the speed of pulses along a spring and the period of transverse standing waves generated in the same spring. These experiments can be helpful in addressing several relevant concepts about the physics of mechanical waves and in overcoming some of the typical student misconceptions in this same field.

A Self-Check System for Mental Health Care based on Nonlinear and Chaos Analysis

NASA Astrophysics Data System (ADS)

Oyama-Higa, Mayumi; Miao, Tiejun; Cheng, Huaichang; Tang, Yuan Guang

2007-11-01

We applied nonlinear and chaos analysis to fingertip pulse wave data. The largest Lyapunov exponent, a measure of the "divergence" of the trajectory of the attractor in phase space, was found to be a useful index of mental health in humans, particularly for the early detection of dementia and depressive psychosis, and for monitoring mental changes in healthy persons. Most of the methods used for assessing mental health are subjective. A few of existing objective methods, such as those using EEG and ECG, for example, are not simple to use and expansive. Therefore, we developed an easy-to-use economical device, a PC mouse with an integrated sensor for measuring the pulse waves, and its required software, to make the measurements. After about 1 min of measurement, the Lyapunov exponent is calculated and displayed as a graph on the PC. An advantage of this system is that the measurements can be made very easily, and hence mental health can be assessed during operating a PC using the pulse wave mouse. Moreover, the measured data can be saved according to the time and date, so diurnal changes and changes over longer time periods can be monitored as a time series and history. At the time the pulse waves are measured, we ask the subject about his or her physical health and mood, and use their responses, along with the Lyapunov exponents, as factors causing variation in the divergence. The changes in the Lyapunov exponent are displayed on the PC as constellation graphs, which we developed to facilitate simpler self-diagnosis and problem resolution.

High-efficiency generation of pulsed Lyman-α radiation by resonant laser wave mixing in low pressure Kr-Ar mixture.

PubMed

Saito, Norihito; Oishi, Yu; Miyazaki, Koji; Okamura, Kotaro; Nakamura, Jumpei; Louchev, Oleg A; Iwasaki, Masahiko; Wada, Satoshi

2016-04-04

We report an experimental generation of ns pulsed 121.568 nm Lyman-α radiation by the resonant nonlinear four-wave mixing of 212.556 nm and 845.015 nm radiation pulses providing a high conversion efficiency 1.7x10^-3 with the output pulse energy 3.6 μJ achieved using a low pressure Kr-Ar mixture. Theoretical analysis shows that this efficiency is achieved due to the advantage of using (i) the high input laser intensities in combination with (ii) the low gas pressure allowing us to avoid the onset of full-scale discharge in the laser focus. In particular, under our experimental conditions the main mechanism of photoionization caused by the resonant 2-photon 212.556 nm radiation excitation of Kr atoms followed by the 1-photon ionization leads to ≈17% loss of Kr atoms and efficiency loss only by the end of the pulse. The energy of free electrons, generated by 212.556 nm radiation via (2 + 1)-photon ionization and accelerated mainly by 845.015 nm radiation, remains during the pulse below the level sufficient for the onset of full-scale discharge by the electron avalanche. Our analysis also suggests that ≈30-fold increase of 845.015 nm pulse energy can allow one to scale up the L-α radiation pulse energy towards the level of ≈100 μJ.

Method for generating a plasma wave to accelerate electrons

DOEpatents

Umstadter, D.; Esarey, E.; Kim, J.K.

1997-06-10

The invention provides a method and apparatus for generating large amplitude nonlinear plasma waves, driven by an optimized train of independently adjustable, intense laser pulses. In the method, optimal pulse widths, interpulse spacing, and intensity profiles of each pulse are determined for each pulse in a series of pulses. A resonant region of the plasma wave phase space is found where the plasma wave is driven most efficiently by the laser pulses. The accelerator system of the invention comprises several parts: the laser system, with its pulse-shaping subsystem; the electron gun system, also called beam source, which preferably comprises photo cathode electron source and RF-LINAC accelerator; electron photo-cathode triggering system; the electron diagnostics; and the feedback system between the electron diagnostics and the laser system. The system also includes plasma source including vacuum chamber, magnetic lens, and magnetic field means. The laser system produces a train of pulses that has been optimized to maximize the axial electric field amplitude of the plasma wave, and thus the electron acceleration, using the method of the invention. 21 figs.

Method for generating a plasma wave to accelerate electrons

DOEpatents

Umstadter, Donald; Esarey, Eric; Kim, Joon K.

1997-01-01

The invention provides a method and apparatus for generating large amplitude nonlinear plasma waves, driven by an optimized train of independently adjustable, intense laser pulses. In the method, optimal pulse widths, interpulse spacing, and intensity profiles of each pulse are determined for each pulse in a series of pulses. A resonant region of the plasma wave phase space is found where the plasma wave is driven most efficiently by the laser pulses. The accelerator system of the invention comprises several parts: the laser system, with its pulse-shaping subsystem; the electron gun system, also called beam source, which preferably comprises photo cathode electron source and RF-LINAC accelerator; electron photo-cathode triggering system; the electron diagnostics; and the feedback system between the electron diagnostics and the laser system. The system also includes plasma source including vacuum chamber, magnetic lens, and magnetic field means. The laser system produces a train of pulses that has been optimized to maximize the axial electric field amplitude of the plasma wave, and thus the electron acceleration, using the method of the invention.

Optimal laser pulse design for transferring the coherent nuclear wave packet of H+2

NASA Astrophysics Data System (ADS)

Zhang, Jun; He, Guang-Qiang; He, Feng

2014-07-01

Within the Franck-Condon approximation, the single ionisation of H2 leaves H+2 in a coherent superposition of 19 nuclear vibrational states. We numerically design an optimal laser pulse train to transfer such a coherent nuclear wave packet to the ground vibrational state of H+2. Frequency analysis of the designed optimal pulse reveals that the transfer principle is mainly an anti-Stokes transition, i.e. the H+2 in 1sσg with excited nuclear vibrational states is first pumped to 2pσg state by the pulse at an appropriate time, and then dumped back to 1sσg with lower excited or ground vibrational states. The simulation results show that the population of the ground state after the transfer is more than 91%. To the best of our knowledge, this is the highest transition probability when the driving laser field is dozens of femtoseconds.

Detection of cerebral ischemia using the power spectrum of the pulse wave measured by near-infrared spectroscopy.

PubMed

Ebihara, Akira; Tanaka, Yuichi; Konno, Takehiko; Kawasaki, Shingo; Fujiwara, Michiyuki; Watanabe, Eiju

2013-10-01

The diagnosis and medical treatment of cerebral ischemia are becoming more important due to the increase in the prevalence of cerebrovascular disease. However, conventional methods of evaluating cerebral perfusion have several drawbacks: they are invasive, require physical restraint, and the equipment is not portable, which makes repeated measurements at the bedside difficult. An alternative method is developed using near-infrared spectroscopy (NIRS). NIRS signals are measured at 44 positions (22 on each side) on the fronto-temporal areas in 20 patients with cerebral ischemia. In order to extract the pulse-wave component, the raw total hemoglobin data recorded from each position are band-pass filtered (0.8 to 2.0 Hz) and subjected to a fast Fourier transform to obtain the power spectrum of the pulse wave. The ischemic region is determined by single-photon emission computed tomography. The pulse-wave power in the ischemic region is compared with that in the symmetrical region on the contralateral side. In 17 cases (85%), the pulse-wave power on the ischemic side is significantly lower than that on the contralateral side, which indicates that the transmission of the pulse wave is attenuated in the region with reduced blood flow. Pulse-wave power might be useful as a noninvasive marker of cerebral ischemia.

Laboratory model of the cardiovascular system for experimental demonstration of pulse wave propagation

NASA Astrophysics Data System (ADS)

Stojadinović, Bojana; Nestorović, Zorica; Djurić, Biljana; Tenne, Tamar; Zikich, Dragoslav; Žikić, Dejan

2017-03-01

The velocity by which a disturbance moves through the medium is the wave velocity. Pulse wave velocity is among the key parameters in hemodynamics. Investigation of wave propagation through the fluid-filled elastic tube has a great importance for the proper biophysical understanding of the nature of blood flow through the cardiovascular system. Here, we present a laboratory model of the cardiovascular system. We have designed an experimental setup which can help medical and nursing students to properly learn and understand basic fluid hemodynamic principles, pulse wave and the phenomenon of wave propagation in blood vessels. Demonstration of wave propagation allowed a real time observation of the formation of compression and expansion waves by students, thus enabling them to better understand the difference between the two waves, and also to measure the pulse wave velocity for different fluid viscosities. The laboratory model of the cardiovascular system could be useful as an active learning methodology and a complementary tool for understanding basic principles of hemodynamics.

Chirped pulse digital holography for measuring the sequence of ultrafast optical wavefronts

NASA Astrophysics Data System (ADS)

Karasawa, Naoki

2018-04-01

Optical setups for measuring the sequence of ultrafast optical wavefronts using a chirped pulse as a reference wave in digital holography are proposed and analyzed. In this method, multiple ultrafast object pulses are used to probe the temporal evolution of ultrafast phenomena and they are interfered with a chirped reference wave to record a digital hologram. Wavefronts at different times can be reconstructed separately from the recorded hologram when the reference pulse can be treated as a quasi-monochromatic wave during the pulse width of each object pulse. The feasibility of this method is demonstrated by numerical simulation.

Forward and Backward Pressure Waveform Morphology in Hypertension.

PubMed

Li, Ye; Gu, Haotian; Fok, Henry; Alastruey, Jordi; Chowienczyk, Philip

2017-02-01

We tested the hypothesis that increased pulse wave reflection and altered backward waveform morphology contribute to increased pulse pressure in subjects with higher pulse pressure compared with lower pulse pressure and to actions of vasoactive drugs to increase pulse pressure. We examined the relationship of backward to forward wave morphology in 158 subjects who were evaluated for hypertension (including some normotensive subjects) divided into 3 groups by central pulse pressure: group 1, 33±6.5 mm Hg; group 2, 45±4.1 mm Hg; and group 3, 64±12.9 mm Hg (means±SD) and in healthy normotensive subjects during administration of inotropic and vasomotor drugs. Aortic pressure and flow in the aortic root were estimated by carotid tonometry and Doppler sonography, respectively. Morphology of the backward wave relative to the forward wave was similar in subjects in the lowest and highest tertiles of pulse pressure. Similar results were seen with the inotropic, vasopressor and vasodilator drugs, dobutamine, norepinephrine, and phentolamine, with the backward wave maintaining a constant ratio to the forward wave. However, nitroglycerin, a drug with a specific action to dilate muscular conduit arteries, reduced the amplitude of the backward wave relative to the forward wave from 0.26±0.018 at baseline to 0.19±0.019 during nitroglycerin 30 μg/min IV (P<0.01). These results are best explained by an approximately constant amount of reflection of the forward wave from the peripheral vasculature. The amount of reflection can be modified by dilation of peripheral muscular conduit arteries but contributes little to increased pulse pressure in hypertension. © 2016 The Authors.

Reproducibility of Regional Pulse Wave Velocity in Healthy Subjects

PubMed Central

Lee, Nak Bum

2009-01-01

Background/Aims Despite the clinical importance and widespread use of pulse wave velocity (PWV), there are no standards for pulse sensors or for system requirements to ensure accurate pulse wave measurement. We assessed the reproducibility of PWV values using a newly developed PWV measurement system. Methods The system used in this study was the PP-1000, which simultaneously provides regional PWV values from arteries at four different sites (carotid, femoral, radial, and dorsalis pedis). Seventeen healthy male subjects without any cardiovascular disease participated in this study. Two observers performed two consecutive measurements in the same subject in random order. To evaluate the reproducibility of the system, two sets of analyses (within-observer and between-observer) were performed. Results The means±SD of PWV for the aorta, arm, and leg were 7.0±1.48, 8.43±1.14, and 8.09±0.98 m/s as measured by observer A and 6.76±1.00, 7.97±0.80, and 7.97±0.72 m/s by observer B, respectively. Between-observer differences for the aorta, arm, and leg were 0.14±0.62, 0.18±0.84, and 0.07±0.86 m/s, respectively, and the correlation coefficients were high, especially for aortic PWV (r=0.93). All the measurements showed significant correlation coefficients, ranging from 0.94 to 0.99. Conclusions The PWV measurement system used in this study provides accurate analysis results with high reproducibility. It is necessary to provide an accurate algorithm for the detection of additional features such as flow wave, reflection wave, and dicrotic notch from a pulse waveform. PMID:19270477

Electromagnetic pulses, localized and causal

NASA Astrophysics Data System (ADS)

Lekner, John

2018-01-01

We show that pulse solutions of the wave equation can be expressed as time Fourier superpositions of scalar monochromatic beam wave functions (solutions of the Helmholtz equation). This formulation is shown to be equivalent to Bateman's integral expression for solutions of the wave equation, for axially symmetric solutions. A closed-form one-parameter solution of the wave equation, containing no backward-propagating parts, is constructed from a beam which is the tight-focus limit of two families of beams. Application is made to transverse electric and transverse magnetic pulses, with evaluation of the energy, momentum and angular momentum for a pulse based on the general localized and causal form. Such pulses can be represented as superpositions of photons. Explicit total energy and total momentum values are given for the one-parameter closed-form pulse.

Generation of spin waves by a train of fs-laser pulses: a novel approach for tuning magnon wavelength.

PubMed

Savochkin, I V; Jäckl, M; Belotelov, V I; Akimov, I A; Kozhaev, M A; Sylgacheva, D A; Chernov, A I; Shaposhnikov, A N; Prokopov, A R; Berzhansky, V N; Yakovlev, D R; Zvezdin, A K; Bayer, M

2017-07-18

Currently spin waves are considered for computation and data processing as an alternative to charge currents. Generation of spin waves by ultrashort laser pulses provides several important advances with respect to conventional approaches using microwaves. In particular, focused laser spot works as a point source for spin waves and allows for directional control of spin waves and switching between their different types. For further progress in this direction it is important to manipulate with the spectrum of the optically generated spin waves. Here we tackle this problem by launching spin waves by a sequence of femtosecond laser pulses with pulse interval much shorter than the relaxation time of the magnetization oscillations. This leads to the cumulative phenomenon and allows us to generate magnons in a specific narrow range of wavenumbers. The wavelength of spin waves can be tuned from 15 μm to hundreds of microns by sweeping the external magnetic field by only 10 Oe or by slight variation of the pulse repetition rate. Our findings expand the capabilities of the optical spin pump-probe technique and provide a new method for the spin wave generation and control.

Autogenerator of beams of charged particles

DOEpatents

Adler, Richard J.; Mazarakis, Michael G.; Miller, Robert B.; Shope, Steven L.; Smith, David L.

1986-01-01

An autogenerating apparatus provides secondary intense relativistic current beam pulses in response to an injected beam pulse. One or more electromagnetic energy storage devices are provided in conjunction with gaps along a beam propagation path for the injected beam pulse. For injected beam pulses which are no longer than double the transit time of electromagnetic waves within the storage devices (which may be resonant cavities), distinct secondary beam pulses are generated by each of the energy storage devices. The beam propagation path, together with the one or more gaps provided therein, operates as a pulse forming transmission line cavity, in which the separate cavities associated with the gaps provide delays for electromagnetic waves generated at the gaps. After doubly traversing the cavity, the electromagnetic waves cause the gap to generate the secondary beam pulses, which are thus delayed by a time interval equal to the double transit time for the induced wave within the cavity.

Autogenerator of beams of charged particles

DOEpatents

Adler, R.J.; Mazarakis, M.G.; Miller, R.M.; Shope, S.L.; Smith, D.L.

1983-10-31

An autogenerating apparatus provides secondary intense relativistic current beam pulses in response to an injected beam pulse. One or more electromagnetic energy storage devices are provided in conjunction with gaps along a beam propagation path for the injected beam pulse. For injected beam pulses which are no longer than double the transit time of electromagnetic waves within the storage devices (which may be resonant cavities), distinct secondary beam pulses are generated by each of the energy storage devices. The beam propagation path, together with the one or more gaps provided therein, operates as a pulse forming transmission line cavity, in which the separate cavities associated with the gaps provide delays for electromagnetic waves generated at the gaps. After doubly traversing the cavity, the electromagnetic waves cause the gap to generate the secondary beam pulses, which are thus delayed by a time interval equal to the double transit time for the induced wave within the cavity.

Direct observation of isolated Damon-Eshbach and backward volume spin-wave packets in ferromagnetic microstripes

PubMed Central

Wessels, Philipp; Vogel, Andreas; Tödt, Jan-Niklas; Wieland, Marek; Meier, Guido; Drescher, Markus

2016-01-01

The analysis of isolated spin-wave packets is crucial for the understanding of magnetic transport phenomena and is particularly interesting for applications in spintronic and magnonic devices, where isolated spin-wave packets implement an information processing scheme with negligible residual heat loss. We have captured microscale magnetization dynamics of single spin-wave packets in metallic ferromagnets in space and time. Using an optically driven high-current picosecond pulse source in combination with time-resolved scanning Kerr microscopy probed by femtosecond laser pulses, we demonstrate phase-sensitive real-space observation of spin-wave packets in confined permalloy (Ni80Fe20) microstripes. Impulsive excitation permits extraction of the dynamical parameters, i.e. phase- and group velocities, frequencies and wave vectors. In addition to well-established Damon-Eshbach modes our study reveals waves with counterpropagating group- and phase-velocities. Such unusual spin-wave motion is expected for backward volume modes where the phase fronts approach the excitation volume rather than emerging out of it due to the negative slope of the dispersion relation. These modes are difficult to excite and observe directly but feature analogies to negative refractive index materials, thus enabling model studies of wave propagation inside metamaterials. PMID:26906113

Baseline aortic pulse wave velocity is associated with central and peripheral pressor responses during the cold pressor test in healthy subjects.

PubMed

Borner, Anastasiya; Murray, Kyle; Trotter, Claire; Pearson, James

2017-07-01

Cold environmental temperatures increase sympathetic nerve activity and blood pressure, and increase the risk of acute cardiovascular events in aged individuals. The acute risk of cardiovascular events increases with aortic pulse wave velocity as well as elevated central and peripheral pulse pressures. The aim of this study was to examine the independent influence of aortic pulse wave velocity upon central and peripheral pressor responses to sympathetic activation via the cold pressor test (CPT). Twenty-two healthy subjects (age: 18-73 years) completed a CPT with the left hand immersed in 2-4°C water for 3 min. During the CPT, central (from: 36 ± 7 to: 51 ± 12 mmHg) and peripheral pulse pressure increased (from: 54 ± 7 to: 66 ± 11; both P  <   0.05). In all subjects the increase in central pulse pressure during the CPT was independently associated with baseline aortic pulse wave velocity ( r 2  = 0.221, P  =   0.027) but not age ( P  >   0.05). In a subset of subjects with higher arterial stiffness, the increase in peripheral pulse pressure during the CPT was independently associated with baseline aortic pulse wave velocity ( r 2  = 0.415, P  =   0.032) but not age ( P  >   0.05). These data indicate that central and peripheral pulse pressure responses during sympathetic activation are positively and independently associated with aortic pulse wave velocity through a wide age range. Decreasing aortic pulse wave velocity in aged individuals with elevated arterial stiffness may help reduce the incidence of acute cardiovascular events upon exposure to cold environmental temperatures. © 2017 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.

Laser pulse self-compression in an active fibre with a finite gain bandwidth under conditions of a nonstationary nonlinear response

NASA Astrophysics Data System (ADS)

Balakin, A. A.; Litvak, A. G.; Mironov, V. A.; Skobelev, S. A.

2018-04-01

We study the influence of a nonstationary nonlinear response of a medium on self-compression of soliton-like laser pulses in active fibres with a finite gain bandwidth. Based on the variational approach, we qualitatively analyse the self-action of the wave packet in the system under consideration in order to classify the main evolution regimes and to determine the minimum achievable laser pulse duration during self-compression. The existence of stable soliton-type structures is shown in the framework of the parabolic approximation of the gain profile (in the approximation of the Gnizburg – Landau equation). An analysis of the self-action of laser pulses in the framework of the nonlinear Schrödinger equation with a sign-constant gain profile demonstrate a qualitative change in the dynamics of the wave field in the case of a nonsta­tionary nonlinear response that shifts the laser pulse spectrum from the amplification region and stops the pulse compression. Expressions for a minimum duration of a soliton-like laser pulse are obtained as a function of the problem parameters, which are in good agreement with the results of numerical simulation.

Some problems of nonlinear waves in solid propellant rocket motors

NASA Technical Reports Server (NTRS)

Culick, F. E. C.

1979-01-01

An approximate technique for analyzing nonlinear waves in solid propellant rocket motors is presented which inexpensively provides accurate results up to amplitudes of ten percent. The connection with linear stability analysis is shown. The method is extended to third order in the amplitude of wave motion in order to study nonlinear stability, or triggering. Application of the approximate method to the behavior of pulses is described.

Effect of viscosity on the wave propagation: Experimental determination of compression and expansion pulse wave velocity in fluid-fill elastic tube.

PubMed

Stojadinović, Bojana; Tenne, Tamar; Zikich, Dragoslav; Rajković, Nemanja; Milošević, Nebojša; Lazović, Biljana; Žikić, Dejan

2015-11-26

The velocity by which the disturbance travels through the medium is the wave velocity. Pulse wave velocity is one of the main parameters in hemodynamics. The study of wave propagation through the fluid-fill elastic tube is of great importance for the proper biophysical understanding of the nature of blood flow through of cardiovascular system. The effect of viscosity on the pulse wave velocity is generally ignored. In this paper we present the results of experimental measurements of pulse wave velocity (PWV) of compression and expansion waves in elastic tube. The solutions with different density and viscosity were used in the experiment. Biophysical model of the circulatory flow is designed to perform measurements. Experimental results show that the PWV of the expansion waves is higher than the compression waves during the same experimental conditions. It was found that the change in viscosity causes a change of PWV for both waves. We found a relationship between PWV, fluid density and viscosity. Copyright © 2015 Elsevier Ltd. All rights reserved.

Advanced Orion Optimized Laser System Analysis

NASA Technical Reports Server (NTRS)

1996-01-01

Contractor shall perform a complete analysis of the potential of the solid state laser in the very long pulse mode (100 ns pulse width, 10-30 hz rep-rate) and in the very short pulse mode (100 ps pulse width 10-30 hz rep rate) concentrating on the operation of the device in the 'hot-rod' mode, where no active cooling the laser operation is attempted. Contractor's calculations shall be made of the phase aberrations which develop during the repped-pulse train, and the results shall feed into the adaptive optics analyses. The contractor shall devise solutions to work around ORION track issues. A final report shall be furnished to the MSFC COTR including all calculations and analysis of estimates of bulk phase and intensity aberration distribution in the laser output beam as a function of time during the repped-pulse train for both wave forms (high-energy/long-pulse, as well as low-energy/short-pulse). Recommendations shall be made for mitigating the aberrations by laser re-design and/or changes in operating parameters of optical pump sources and/or designs.

[De-noising and measurement of pulse wave velocity of the wavelet].

PubMed

Liu, Baohua; Zhu, Honglian; Ren, Xiaohua

2011-02-01

Pulse wave velocity (PWV) is a vital index of the cardiovascular pathology, so that the accurate measurement of PWV can be of benefit for prevention and treatment of cardiovascular diseases. The noise in the measure system of pulse wave signal, rounding error and selection of the recording site all cause errors in the measure result. In this paper, with wavelet transformation to eliminate the noise and to raise the precision, and with the choice of the point whose slope was maximum as the recording site of the reconstructing pulse wave, the measuring system accuracy was improved.

Optical Production and Detection of Ultrasonic Waves in Metals for Nondestructive Testing

NASA Technical Reports Server (NTRS)

Morrison, R. A.

1972-01-01

Ultrasonic waves were produced by striking the surface of a metal with the focused one-joule pulse of a Q-switched ruby laser. Rayleigh (surface) waves and longitudinal waves were detected with conventional transducers. Optical methods of detection were tested and developed. Rayleigh waves were produced with an oscillator and transducer. They were optically detected on curved polished surfaces, and on unpolished surfaces. The technique uses a knife edge to detect small angle changes of the surface as the wave pulse passes the illuminated spot. Optical flaw detection using pulse echo and attenuation is demonstrated.

Observed stratospheric downward reflection, and its relation to upward pulses of wave activity

NASA Astrophysics Data System (ADS)

Harnik, N.

2009-04-01

We examine the differences between observed stratospheric vertical wave reflection and wave absorption events, which differ in that the wave induced deceleration remains confined to upper levels in the former. The two types of events signify two types of stratospheric winter dynamics, associated with different downward coupling to the troposphere (Perlwitz and Harnik, 2004). Using time lag composites, we find that the main factor influencing which event will occur is the duration, in time, of the upward pulse of wave activity entering the stratosphere from the troposphere. Short pulses accelerate the flow at their trailing edge in the lower stratosphere while they decelerate it at upper levels, resulting in a vertical shear reversal, and corresponding downward reflection, while long pulses continue decelerating the vortex at progressively lower levels. The confinement of deceleration to upper levels for short wave forcing pulses is also found in an idealized model of an interaction between a planetary wave and the stratospheric vortex, though some aspects of the wave geometry evolution, and thus vertical reflection, are not captured realistically in the model. The results suggest the stratospheric influence on the type of wave interaction, in reality, is indirect - through a possible effect on the duration of upward wave fluxes through the tropopause.

Monitoring and analysis of thermal deformation waves with a high-speed phase measurement system.

PubMed

Taylor, Lucas; Talghader, Joseph

2015-10-20

Thermal effects in optical substrates are vitally important in determining laser damage resistance in long-pulse and continuous-wave laser systems. Thermal deformation waves in a soda-lime-silica glass substrate have been measured using high-speed interferometry during a series of laser pulses incident on the surface. Two-dimensional images of the thermal waves were captured at a rate of up to six frames per thermal event using a quantitative phase measurement method. The system comprised a Mach-Zehnder interferometer, along with a high-speed camera capable of up to 20,000 frames-per-second. The sample was placed in the interferometer and irradiated with 100 ns, 2 kHz Q-switched pulses from a high-power Nd:YAG laser operating at 1064 nm. Phase measurements were converted to temperature using known values of thermal expansion and temperature-dependent refractive index for glass. The thermal decay at the center of the thermal wave was fit to a function derived from first principles with excellent agreement. Additionally, the spread of the thermal distribution over time was fit to the same function. Both the temporal decay fit and the spatial fit produced a thermal diffusivity of 5×10^-7  m²/s.

Human Pulse Wave Measurement by MEMS Electret Condenser Microphone

NASA Astrophysics Data System (ADS)

Nomura, Shusaku; Hanasaka, Yasushi; Ishiguro, Tadashi; Ogawa, Hiroshi

A micro Electret Condenser Microphone (ECM) fabricated by Micro Electro Mechanical System (MEMS) technology was employed as a novel apparatus for human pulse wave measurement. Since ECM frequency response characteristic, i.e. sensitivity, logically maintains a constant level at lower than the resonance frequency (stiffness control), the slightest pressure difference at around 1.0Hz generated by human pulse wave is expected to detect by MEMS-ECM. As a result of the verification of frequency response of MEMS-ECM, it was found that -20dB/dec of reduction in the sensitivity around 1.0Hz was engendered by a high input-impedance amplifier, i.e. the field effect transistor (FET), mounted near MEMS chip for amplifying tiny ECM signal. Therefore, MEMS-ECM is assumed to be equivalent with a differentiation circuit at around human pulse frequency. Introducing compensation circuit, human pulse wave was successfully obtained. In addition, the radial and ulnar artery tracing, and pulse wave velocity measurement at forearm were demonstrated; as illustrating a possible application of this micro device.

Arterial wave reflection and aortic valve calcification in an elderly community-based cohort.

PubMed

Sera, Fusako; Russo, Cesare; Iwata, Shinichi; Jin, Zhezhen; Rundek, Tatjana; Elkind, Mitchell S V; Homma, Shunichi; Sacco, Ralph L; Di Tullio, Marco R

2015-04-01

Aortic valve calcification (AVC) without stenosis is common in the elderly, is associated with cardiovascular morbidity and mortality, and may progress to aortic valve stenosis. Arterial stiffness and pulse-wave reflection are important components of proximal aortic hemodynamics, but their relationship with AVC is not established. To investigate the relationship of arterial wave reflection and stiffness with AVC, pulse wave analysis and AVC evaluation by echocardiography were performed in 867 participants from the Cardiovascular Abnormalities and Brain Lesions study. Participants were divided into four categories on the basis of the severity and extent of AVC: (1) none or mild focal AVC, (2) mild diffuse AVC, (3) moderate to severe focal AVC, and (4) moderate to severe diffuse AVC. Central blood pressures and pulse pressure, total arterial compliance, augmentation index, and time to wave reflection were assessed using applanation tonometry. Indicators of arterial stiffness and wave reflection were significantly associated with AVC severity, except for central systolic and diastolic pressures and time to reflection. After adjustment for pertinent covariates (age, sex, race/ethnicity, and estimated glomerular filtration rate), only augmentation pressure (P = .02) and augmentation index (P = .002) were associated with the severity of AVC. Multivariate logistic regression analysis revealed that augmentation pressure (odds ratio per mm Hg, 1.14; 95% confidence interval, 1.02-1.27; P = .02) and augmentation index (odds ratio per percentage point, 1.07; 95% confidence interval, 1.01-1.13; P = .02) were associated with an increased risk for moderate to severe diffuse AVC, even when central blood pressure value was included in the same model. Arterial wave reflection is associated with AVC severity, independent of blood pressure values. Increased contribution of wave reflection to central blood pressure could be involved in the process leading to AVC. Copyright © 2015 American Society of Echocardiography. Published by Elsevier Inc. All rights reserved.

Role of thermal stresses on pulsed laser irradiation of thin films under conditions of microbump formation and nonvaporization forward transfer

NASA Astrophysics Data System (ADS)

Meshcheryakov, Yuri P.; Shugaev, Maxim V.; Mattle, Thomas; Lippert, Thomas; Bulgakova, Nadezhda M.

2013-11-01

This paper presents a theoretical analysis of the processes in thin solid films irradiated by short and ultrashort laser pulses in the regimes of film structuring and laser-induced forward transfer. The regimes are considered at which vaporization of the film materials is insignificant and film dynamics is governed mainly by mechanical processes. Thermoelastoplastic modeling has been performed for a model film in one- and two-dimensional geometries. A method has been proposed to estimate the height of microbumps produced by nanosecond laser irradiation of solid films. Contrary to femtosecond laser pulses, in nanosecond pulse regimes, stress waves across the film are weak and cannot induce film damage. The main role in laser-induced dynamics of irradiated films is played by radial thermal stresses which lead to the formation of a bending wave propagating along the film and drawing the film matter to the center of the irradiation spot. The bending wave dynamics depends on the hardness of the substrate underlying the film. The causes of the receiver substrate damage sometimes observed upon laser-induced forward transfer in the scheme of the direct contact between the film and the receiver are discussed.

Slow-wave propagation on monolithic microwave integrated circuits with layered and non-layered structures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tzuang, C.K.C.

1986-01-01

Various MMIC (monolithic microwave integrated circuit) planar waveguides have shown possible existence of a slow-wave propagation. In many practical applications of these slow-wave circuits, the semiconductor devices have nonuniform material properties that may affect the slow-wave propagation. In the first part of the dissertation, the effects of the nonuniform material properties are studied by a finite-element method. In addition, the transient pulse excitations of these slow-wave circuits also have great theoretical and practical interests. In the second part, the time-domain analysis of a slow-wave coplanar waveguide is presented.

Measurement of Blood Pressure Using an Arterial Pulsimeter Equipped with a Hall Device

PubMed Central

Lee, Sang-Suk; Nam, Dong-Hyun; Hong, You-Sik; Lee, Woo-Beom; Son, Il-Ho; Kim, Keun-Ho; Choi, Jong-Gu

2011-01-01

To measure precise blood pressure (BP) and pulse rate without using a cuff, we have developed an arterial pulsimeter consisting of a small, portable apparatus incorporating a Hall device. Regression analysis of the pulse wave measured during testing of the arterial pulsimeter was conducted using two equations of the BP algorithm. The estimated values of BP obtained by the cuffless arterial pulsimeter over 5 s were compared with values obtained using electronic or liquid mercury BP meters. The standard deviation between the estimated values and the measured values for systolic and diastolic BP were 8.3 and 4.9, respectively, which are close to the range of values of the BP International Standard. Detailed analysis of the pulse wave measured by the cuffless radial artery pulsimeter by detecting changes in the magnetic field can be used to develop a new diagnostic algorithm for BP, which can be applied to new medical apparatus such as the radial artery pulsimeter. PMID:22319381

Simulation of the excitation of quasi-plane wake waves in a plasma by a resonant sequence of laser pulses with a variable envelope

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kalinnikova, E. I.; Levchenko, V. D.

2008-04-15

Results are presented from full-scale numerical simulations of the excitation of wake waves by a sequence of weakly relativistic laser pulses in a subcritical plasma. Computations were carried out with a 2D3V version of the SUR-CA code that is based on the local-recursive nonlocal-asynchronous algorithm of the particle-in-cell method. The parameters of a train of laser pulses were chosen to correspond to the resonant excitation of the wake field. The curvature of the envelope of the pulses was chosen to depend on the number of the pulse in the train. Numerical simulations showed that there are plane waves during themore » first period of the plasma wave behind the pulse train.« less

Attosecond electromagnetic pulse generation due to the interaction of a relativistic soliton with a breaking-wake plasma wave.

PubMed

Isanin, A V; Bulanov, S S; Kamenets, F F; Pegoraro, F

2005-03-01

During the interaction of a low-frequency relativistic soliton with the electron density modulations of a wake plasma wave, part of the electromagnetic energy of the soliton is reflected in the form of an extremely short and ultraintense electromagnetic pulse. We calculate the spectra of the reflected and of the transmitted electromagnetic pulses analytically. The reflected wave has the form of a single cycle attosecond pulse.

Strong sub-terahertz surface waves generated on a metal wire by high-intensity laser pulses

PubMed Central

Tokita, Shigeki; Sakabe, Shuji; Nagashima, Takeshi; Hashida, Masaki; Inoue, Shunsuke

2015-01-01

Terahertz pulses trapped as surface waves on a wire waveguide can be flexibly transmitted and focused to sub-wavelength dimensions by using, for example, a tapered tip. This is particularly useful for applications that require high-field pulses. However, the generation of strong terahertz surface waves on a wire waveguide remains a challenge. Here, ultrafast field propagation along a metal wire driven by a femtosecond laser pulse with an intensity of 1018 W/cm2 is characterized by femtosecond electron deflectometry. From experimental and numerical results, we conclude that the field propagating at the speed of light is a half-cycle transverse-magnetic surface wave excited on the wire and a considerable portion of the kinetic energy of laser-produced fast electrons can be transferred to the sub-surface wave. The peak electric field strength of the surface wave and the pulse duration are estimated to be 200 MV/m and 7 ps, respectively. PMID:25652694

Stringlike Pulse Quantification Study by Pulse Wave in 3D Pulse Mapping

PubMed Central

Chung, Yu-Feng; Yeh, Cheng-Chang; Si, Xiao-Chen; Chang, Chien-Chen; Hu, Chung-Shing; Chu, Yu-Wen

2012-01-01

Abstract Background A stringlike pulse is highly related to hypertension, and many classification approaches have been proposed in which the differentiation pulse wave (dPW) can effectively classify the stringlike pulse indicating hypertension. Unfortunately, the dPW method cannot distinguish the spring stringlike pulse from the stringlike pulse so labeled by physicians in clinics. Design By using a Bi-Sensing Pulse Diagnosis Instrument (BSPDI), this study proposed a novel Plain Pulse Wave (PPW) to classify a stringlike pulse based on an array of pulse signals, mimicking a Traditional Chinese Medicine physician's finger-reading skill. Results In comparison to PPWs at different pulse taking positions, phase delay Δθand correlation coefficient r can be elucidated as the quantification parameters of stringlike pulse. As a result, the recognition rates of a hypertensive stringlike pulse, spring stringlike pulse, and non–stringlike pulse are 100%, 100%, 77% for PPW and 70%, 0%, 59% for dPW, respectively. Conclusions Integrating dPW and PPW can unify the classification of stringlike pulse including hypertensive stringlike pulse and spring stringlike pulse. Hence, the proposed novel method, PPW, enhances quantification of stringlike pulse. PMID:23057481

Oscillometric analysis compared with cardiac magnetic resonance for the assessment of aortic pulse wave velocity in patients with myocardial infarction.

PubMed

Feistritzer, Hans-Josef; Klug, Gert; Reinstadler, Sebastian J; Reindl, Martin; Mayr, Agnes; Schocke, Michael; Metzler, Bernhard

2016-09-01

Measurement of aortic pulse wave velocity (PWV) is the gold standard for assessment of aortic stiffness. In patients with ST-segment elevation myocardial infarction (STEMI), high aortic PWV has deleterious effects on the myocardium. In the present study, we compared a novel oscillometric device with cardiac magnetic resonance (CMR) imaging for the assessment of aortic PWV in STEMI patients. We measured aortic PWV in 60 reperfused STEMI patients using two different methods. The oscillometric method (PWVOSC) is based on mathematical transformation of brachial pressure waveforms, oscillometrically determined using a common cuff (Mobil-O-Graph, I.E.M., Stolberg, North Rhine-Westphalia, Germany). Phase-contrast CMR imaging (1.5 T scanner, Siemens, Erlangen, Bavaria, Germany) at the level of the ascending and abdominal aorta was performed to determine CMR-derived pulse wave velocity with the use of the transit time method. The mean age of the study population was 57 ± 11 years; 11 (18%) were women. Median PWVOSC was 7.4 m/s (interquartile range 6.8-8.9 m/s), and median CMR-derived pulse wave velocity was 6.3 m/s (interquartile range 5.7-8.2 m/s) (P < 0.001). A strong correlation was detected between both methods (r = 0.724, P < 0.001). Bland-Altman analysis revealed a bias of 0.62 m/s (upper and lower limit of agreement: 3.84 and -2.61 m/s). The coefficient of variation between both methods was 21%. In reperfused STEMI patients, aortic PWV assessed noninvasively by transformation of brachial pressure waveforms showed an acceptable agreement with the CMR-derived transit time method.

White matter hyperintensities in migraine: Clinical significance and central pulsatile hemodynamic correlates.

PubMed

Cheng, Chun-Yu; Cheng, Hao-Min; Chen, Shih-Pin; Chung, Chih-Ping; Lin, Yung-Yang; Hu, Han-Hwa; Chen, Chen-Huan; Wang, Shuu-Jiun

2018-06-01

Background The role of central pulsatile hemodynamics in the pathogenesis of white matter hyperintensities in migraine patients has not been clarified. Methods Sixty patients with migraine (20-50 years old; women, 68%) without overt vascular risk factors and 30 demographically-matched healthy controls were recruited prospectively. Cerebral white matter hyperintensities volume was determined by T1-weighted magnetic resonance imaging with CUBE-fluid-attenuated-inversion-recovery sequences. Central systolic blood pressure, carotid-femoral pulse wave velocity, and carotid augmentation index were measured by applanation tonometry. Carotid pulsatility index was derived from Doppler ultrasound carotid artery flow analysis. Results Compared to the controls, the migraine patients had higher white matter hyperintensities frequency (odds ratio, 2.75; p = 0.04) and greater mean white matter hyperintensities volume (0.174 vs. 0.049, cm 3 , p = 0.04). Multivariable regression analysis showed that white matter hyperintensities volume in migraine patients was positively associated with central systolic blood pressure ( p = 0.04) and carotid-femoral pulse wave velocity ( p < 0.001), but negatively associated with carotid pulsatility index ( p = 0.04) after controlling for potential confounding factors. The interaction effects observed indicated that the influence of carotid-femoral pulse wave velocity ( p = 0.004) and central systolic blood pressure ( p = 0.03) on white matter hyperintensities formation was greater for the lower-carotid pulsatility index subgroup of migraine patients. White matter hyperintensities volume in migraine patients increased with decreasing carotid pulsatility index and with increasing central systolic blood pressure or carotid-femoral pulse wave velocity. Conclusions White matter hyperintensities are more common in patients with migraine than in healthy controls. Increased aortic stiffness or central systolic blood pressure in the presence of low intracranial artery resistance may predispose patients with migraine to white matter hyperintensities formation.

Arterial stiffness in people with Type 2 diabetes and obstructive sleep apnoea.

PubMed

Hvelplund Kristiansen, M; Banghøj, A M; Laugesen, E; Tarnow, L

2018-05-15

To examine whether people with Type 2 diabetes with concurrent obstructive sleep apnoea have increased arterial stiffness as compared with people with Type 2 diabetes without obstructive sleep apnoea. In a study with a case-control design, 40 people with Type 2 diabetes and treatment-naïve moderate to severe obstructive sleep apnoea (Apnoea-Hypopnoea Index ≥15) and a control group of 31 people with Type 2 diabetes without obstructive sleep apnoea (Apnoea-Hypopnoea Index <5) were examined. Obstructive sleep apnoea status was evaluated using the ApneaLink ® + home-monitoring device (Resmed Inc., San Diego, CA, USA), providing the Apnoea-Hypopnoea Index scores. Arterial stiffness was assessed according to carotid-femoral pulse wave velocity using the Sphygmocor device and the oscillometric Mobil-O-Graph ® (I.E.M. GmbH, Stolberg, Germany). Carotid-femoral pulse wave velocity was not significantly different between participants with Type 2 diabetes with obstructive sleep apnoea and those without obstructive sleep apnoea (10.7±2.2 m/s vs 10.3±2.1 m/s; P=0.513), whereas oscillometric pulse wave velocity was significantly higher in participants with Type 2 diabetes with obstructive sleep apnoea than in those without obstructive sleep apnoea (9.5±1.0 m/s vs 8.6±1.4 m/s; P=0.002). In multiple regression analysis, age (P=0.002), gender (men; P=0.018) and HbA 1c (P=0.027) were associated with carotid-femoral pulse wave velocity, and systolic blood pressure (P=0.004) and age (P<0.001) were associated with oscillometric pulse wave velocity. After adjustment, presence of obstructive sleep apnoea was not independently associated with pulse wave velocity whether assessed by tonometry or oscillometry. In conclusion, the present study did not find an age- and blood pressure-independent association between moderate to severe obstructive sleep apnoea and arterial stiffness in non-sleepy people with Type 2 diabetes. (Clinical trial registration number: NCT02482584). © 2018 Diabetes UK.

Soliton radiation beat analysis of optical pulses generated from two continuous-wave lasers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zajnulina, M.; Giannone, D.; Haynes, R.

We propose a fibre-based approach for generation of optical frequency combs (OFCs) with the aim of calibration of astronomical spectrographs in the low and medium-resolution range. This approach includes two steps: in the first step, an appropriate state of optical pulses is generated and subsequently moulded in the second step delivering the desired OFC. More precisely, the first step is realised by injection of two continuous-wave (CW) lasers into a conventional single-mode fibre, whereas the second step generates a broad OFC by using the optical solitons generated in step one as initial condition. We investigate the conversion of a bichromaticmore » input wave produced by two initial CW lasers into a train of optical solitons, which happens in the fibre used as step one. Especially, we are interested in the soliton content of the pulses created in this fibre. For that, we study different initial conditions (a single cosine-hump, an Akhmediev breather, and a deeply modulated bichromatic wave) by means of soliton radiation beat analysis and compare the results to draw conclusion about the soliton content of the state generated in the first step. In case of a deeply modulated bichromatic wave, we observed the formation of a collective soliton crystal for low input powers and the appearance of separated solitons for high input powers. An intermediate state showing the features of both, the soliton crystal and the separated solitons, turned out to be most suitable for the generation of OFC for the purpose of calibration of astronomical spectrographs.« less

Soliton radiation beat analysis of optical pulses generated from two continuous-wave lasers.

PubMed

Zajnulina, M; Böhm, M; Blow, K; Rieznik, A A; Giannone, D; Haynes, R; Roth, M M

2015-10-01

We propose a fibre-based approach for generation of optical frequency combs (OFCs) with the aim of calibration of astronomical spectrographs in the low and medium-resolution range. This approach includes two steps: in the first step, an appropriate state of optical pulses is generated and subsequently moulded in the second step delivering the desired OFC. More precisely, the first step is realised by injection of two continuous-wave (CW) lasers into a conventional single-mode fibre, whereas the second step generates a broad OFC by using the optical solitons generated in step one as initial condition. We investigate the conversion of a bichromatic input wave produced by two initial CW lasers into a train of optical solitons, which happens in the fibre used as step one. Especially, we are interested in the soliton content of the pulses created in this fibre. For that, we study different initial conditions (a single cosine-hump, an Akhmediev breather, and a deeply modulated bichromatic wave) by means of soliton radiation beat analysis and compare the results to draw conclusion about the soliton content of the state generated in the first step. In case of a deeply modulated bichromatic wave, we observed the formation of a collective soliton crystal for low input powers and the appearance of separated solitons for high input powers. An intermediate state showing the features of both, the soliton crystal and the separated solitons, turned out to be most suitable for the generation of OFC for the purpose of calibration of astronomical spectrographs.

Soliton radiation beat analysis of optical pulses generated from two continuous-wave lasers

NASA Astrophysics Data System (ADS)

Zajnulina, M.; Böhm, M.; Blow, K.; Rieznik, A. A.; Giannone, D.; Haynes, R.; Roth, M. M.

2015-10-01

We propose a fibre-based approach for generation of optical frequency combs (OFCs) with the aim of calibration of astronomical spectrographs in the low and medium-resolution range. This approach includes two steps: in the first step, an appropriate state of optical pulses is generated and subsequently moulded in the second step delivering the desired OFC. More precisely, the first step is realised by injection of two continuous-wave (CW) lasers into a conventional single-mode fibre, whereas the second step generates a broad OFC by using the optical solitons generated in step one as initial condition. We investigate the conversion of a bichromatic input wave produced by two initial CW lasers into a train of optical solitons, which happens in the fibre used as step one. Especially, we are interested in the soliton content of the pulses created in this fibre. For that, we study different initial conditions (a single cosine-hump, an Akhmediev breather, and a deeply modulated bichromatic wave) by means of soliton radiation beat analysis and compare the results to draw conclusion about the soliton content of the state generated in the first step. In case of a deeply modulated bichromatic wave, we observed the formation of a collective soliton crystal for low input powers and the appearance of separated solitons for high input powers. An intermediate state showing the features of both, the soliton crystal and the separated solitons, turned out to be most suitable for the generation of OFC for the purpose of calibration of astronomical spectrographs.

Particle energy distributions and metastable atoms in transient low pressure interpulse microwave plasma

NASA Astrophysics Data System (ADS)

Pandey, Shail; Nath Patel, Dudh; Ram Baitha, Anuj; Bhattacharjee, Sudeep

2015-12-01

The electron energies and its distribution function are measured in non-equilibrium transient pulsed microwave plasmas in the interpulse regime using a retarding field electron energy analyzer. The plasmas are driven to different initial conditions by varying the electromagnetic (EM) wave pulse duration, peak power, or the wave frequency. Two cases of wave excitation are investigated: (i) short-pulse (pulse duration, t w ~ 1 μs), high-power (~60 kW) waves of 9.45 GHz and (ii) medium-pulse (t w ~ 20 μs), and moderate power waves of ~3 kW at 2.45 GHz. It is found that high-power, short-duration pulses lead to a significantly different electron energy probability function (EEPF) in the interpulse phase—a Maxwellian with a bump on the tail, although the average energy per pulse (~60 mJ) is maintained the same in the two modes of wave excitation. Electrons with energies  >250 eV are found to exist in the discharge in the both cases. Another subset of experiments is performed to delineate the effect of the wave frequency and the peak power on EEPF. A traveling wave tube (TWT) amplifier based microwave source for generating pulsed plasma (t w  =  230 μs) in a wide frequency range (6-18 GHz) is employed for this purpose. Further experiments on measurements of metastable density using optical emission spectroscopy and ion energy analyzer have been carried out. By tailoring the EEPF of the transient plasma and metastable densities, new applications in plasma processing, chemistry and biology can be realized in the interpulse phase of the discharge.

Engineering studies of vectorcardiographs in blood pressure measuring systems, appendix 2

NASA Technical Reports Server (NTRS)

Mark, R. G.

1975-01-01

The development of a cardiovascular monitoring system to noninvasively monitor the blood pressure and heart rate using pulse wave velocity was described. The following topics were covered: (1) pulse wave velocity as a measure of arterial blood pressure, (2) diastolic blood pressure and pulse wave velocity in humans, (3) transducer development for blood pressure measuring device, and (4) cardiovascular monitoring system. It was found, in experiments on dogs, that the pulse wave velocity is linearly related to diastolic blood pressure over a wide range of blood pressure and in the presence of many physiological perturbations. A similar relationship was observed in normal, young human males over a moderate range of pressures. Past methods for monitoring blood pressure and a new method based on pulse wave velocity determination were described. Two systems were tested: a Doppler ultrasonic transducer and a photoelectric plethysmograph. A cardiovascular monitoring system was described, including operating instructions.

Mach 5 bow shock control by a nanosecond pulse surface dielectric barrier discharge

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nishihara, M.; Takashima, K.; Rich, J. W.

2011-06-15

Bow shock perturbations in a Mach 5 air flow, produced by low-temperature, nanosecond pulse, and surface dielectric barrier discharge (DBD), are detected by phase-locked schlieren imaging. A diffuse nanosecond pulse discharge is generated in a DBD plasma actuator on a surface of a cylinder model placed in air flow in a small scale blow-down supersonic wind tunnel. Discharge energy coupled to the actuator is 7.3-7.8 mJ/pulse. Plasma temperature inferred from nitrogen emission spectra is a few tens of degrees higher than flow stagnation temperature, T = 340 {+-} 30 K. Phase-locked Schlieren images are used to detect compression waves generatedmore » by individual nanosecond discharge pulses near the actuator surface. The compression wave propagates upstream toward the baseline bow shock standing in front of the cylinder model. Interaction of the compression wave and the bow shock causes its displacement in the upstream direction, increasing shock stand-off distance by up to 25%. The compression wave speed behind the bow shock and the perturbed bow shock velocity are inferred from the Schlieren images. The effect of compression waves generated by nanosecond discharge pulses on shock stand-off distance is demonstrated in a single-pulse regime (at pulse repetition rates of a few hundred Hz) and in a quasi-continuous mode (using a two-pulse sequence at a pulse repetition rate of 100 kHz). The results demonstrate feasibility of hypersonic flow control by low-temperature, repetitive nanosecond pulse discharges.« less

Potential of M-Wave Elicited by Double Pulse for Muscle Fatigue Evaluation in Intermittent Muscle Activation by Functional Electrical Stimulation for Motor Rehabilitation

PubMed Central

Miura, Naoto; Watanabe, Takashi

2016-01-01

Clinical studies on application of functional electrical stimulation (FES) to motor rehabilitation have been increasing. However, muscle fatigue appears early in the course of repetitive movement production training by FES. Although M-wave variables were suggested to be reliable indices of muscle fatigue in long lasting constant electrical stimulation under the isometric condition, the ability of M-wave needs more studies under intermittent stimulation condition, because the intervals between electrical stimulations help recovery of muscle activation level. In this paper, M-waves elicited by double pulses were examined in muscle fatigue evaluation during repetitive movements considering rehabilitation training with surface electrical stimulation. M-waves were measured under the two conditions of repetitive stimulation: knee extension force production under the isometric condition and the dynamic movement condition by knee joint angle control. Amplitude of M-wave elicited by the 2nd pulse of a double pulse decreased during muscle fatigue in both measurement conditions, while the change in M-waves elicited by single pulses in a stimulation burst was not relevant to muscle fatigue in repeated activation with stimulation interval of 1 s. Fatigue index obtained from M-waves elicited by 2nd pulses was suggested to provide good estimation of muscle fatigue during repetitive movements with FES. PMID:27110556

Efficient and broadband Stokes wave generation by degenerate four-wave mixing at the mid-infrared wavelength in a silica photonic crystal fiber.

PubMed

Yuan, Jinhui; Sang, Xinzhu; Wu, Qiang; Zhou, Guiyao; Yu, Chongxiu; Wang, Kuiru; Yan, Binbin; Han, Ying; Farrell, Gerald; Hou, Lantian

2013-12-15

Based on degenerate four-wave mixing (FWM), the broadband Stokes waves are efficiently generated at the mid-infrared wavelength above 2 μm, for the first time to our knowledge, by coupling the femtosecond pulses into the fundamental mode of a silica photonic crystal fiber designed and fabricated in our laboratory. Influences of the power and wavelength of pump pulses on the phase-matched frequency conversion process are discussed. When pump pulses with central wavelength of 815 nm and average power of 300 mW are used, the output power ratio of the Stokes wave generated at 2226 nm and the residual pump wave P(s)/P(res) is estimated to be 10.8:1, and the corresponding conversion efficiency η(s) and bandwidth B(s) of the Stokes wave can be up to 26% and 33 nm, respectively. The efficient and broadband Stokes waves can be used as the ultrashort pulse sources for mid-infrared photonics and spectroscopy.

Rotary wave-ejector enhanced pulse detonation engine

NASA Astrophysics Data System (ADS)

Nalim, M. R.; Izzy, Z. A.; Akbari, P.

2012-01-01

The use of a non-steady ejector based on wave rotor technology is modeled for pulse detonation engine performance improvement and for compatibility with turbomachinery components in hybrid propulsion systems. The rotary wave ejector device integrates a pulse detonation process with an efficient momentum transfer process in specially shaped channels of a single wave-rotor component. In this paper, a quasi-one-dimensional numerical model is developed to help design the basic geometry and operating parameters of the device. The unsteady combustion and flow processes are simulated and compared with a baseline PDE without ejector enhancement. A preliminary performance assessment is presented for the wave ejector configuration, considering the effect of key geometric parameters, which are selected for high specific impulse. It is shown that the rotary wave ejector concept has significant potential for thrust augmentation relative to a basic pulse detonation engine.

Solitary waves in morphogenesis: Determination fronts as strain-cued strain transformations among automatous cells

NASA Astrophysics Data System (ADS)

Cox, Brian N.; Landis, Chad M.

2018-02-01

We present a simple theory of a strain pulse propagating as a solitary wave through a continuous two-dimensional population of cells. A critical strain is assumed to trigger a strain transformation, while, simultaneously, cells move as automata to tend to restore a preferred cell density. We consider systems in which the strain transformation is a shape change, a burst of proliferation, or the commencement of growth (which changes the shape of the population sheet), and demonstrate isomorphism among these cases. Numerical and analytical solutions describe a strain pulse whose height does not depend on how the strain disturbance was first launched, or the rate at which the strain transformation is achieved, or the rate constant in the rule for the restorative cell motion. The strain pulse is therefore very stable, surviving the imposition of strong perturbations: it would serve well as a timing signal in development. The automatous wave formulation is simple, with few model parameters. A strong case exists for the presence of a strain pulse during amelogenesis. Quantitative analysis reveals a simple relationship between the velocity of the leading edge of the pulse in amelogenesis and the known speed of migration of ameloblast cells. This result and energy arguments support the depiction of wave motion as an automatous cell response to strain, rather than as a response to an elastic energy gradient. The theory may also contribute to understanding the determination front in somitogenesis, moving fronts of convergent-extension transformation, and mitotic wavefronts in the syncytial drosophila embryo.

New Magnetic Materials and Phenomena for Radar and Microwave Signal Processing Devices - Bulk and Thin Film Ferrites and Metallic Films

DTIC Science & Technology

2009-02-15

Magnon scattered light generally experiences a 90° rotation in polarization from the incident beam. The wave- vector selective BLS measurements...filters, phase locked microwave pulse sources, microwave and millimeter wave devices such as isolators, circulators, phase shifters, secure signal...Wave vector selective Brillouin light scattering measurements and analysis, " C. L. Ordofiez-Romero, B. A. Kalinikos, P. Krivosik, Wei Tong, P

Chirped-Pulse Millimeter-Wave Spectroscopy of Rydberg-Rydberg Transitions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Prozument, Kirill; Colombo, Anthony P.; Zhou Yan

2011-09-30

Transitions between Rydberg states of Ca atoms, in a pulsed, supersonic atomic beam, are directly detected by chirped-pulse millimeter-wave spectroscopy. Broadband, high-resolution spectra with accurate relative intensities are recorded instantly. Free induction decay (FID) of atoms, polarized by the chirped pulse, at their Rydberg-Rydberg transition frequencies, is heterodyne detected, averaged in the time domain, and Fourier transformed into the frequency domain. Millimeter-wave transient nutations are observed, and the possibility of FID evolving to superradiance is discussed.

Phase and frequency structure of superradiance pulses generated by relativistic Ka-band backward-wave oscillator

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rostov, V. V.; Romanchenko, I. V.; Elchaninov, A. A.

2016-08-15

Phase and frequency stability of electromagnetic oscillations in sub-gigawatt superradiance (SR) pulses generated by an extensive slow-wave structure of a relativistic Ka-band backward-wave oscillator were experimentally investigated. Data on the frequency tuning and radiation phase stability of SR pulses with a variation of the energy and current of electron beam were obtained.

Electro-optic Q-switch

NASA Technical Reports Server (NTRS)

Zou, Yingyin (Inventor); Chen, Qiushui (Inventor); Zhang, Run (Inventor); Jiang, Hua (Inventor)

2006-01-01

An electro-optic Q-switch for generating sequence of laser pulses was disclosed. The Q-switch comprises a quadratic electro-optic material and is connected with an electronic unit generating a radio frequency wave with positive and negative pulses alternatively. The Q-switch is controlled by the radio frequency wave in such a way that laser pulse is generated when the radio frequency wave changes its polarity.

Underwater acoustic wave generation by filamentation of terawatt ultrashort laser pulses.

PubMed

Jukna, Vytautas; Jarnac, Amélie; Milián, Carles; Brelet, Yohann; Carbonnel, Jérôme; André, Yves-Bernard; Guillermin, Régine; Sessarego, Jean-Pierre; Fattaccioli, Dominique; Mysyrowicz, André; Couairon, Arnaud; Houard, Aurélien

2016-06-01

Acoustic signals generated by filamentation of ultrashort terawatt laser pulses in water are characterized experimentally. Measurements reveal a strong influence of input pulse duration on the shape and intensity of the acoustic wave. Numerical simulations of the laser pulse nonlinear propagation and the subsequent water hydrodynamics and acoustic wave generation show that the strong acoustic emission is related to the mechanism of superfilamention in water. The elongated shape of the plasma volume where energy is deposited drives the far-field profile of the acoustic signal, which takes the form of a radially directed pressure wave with a single oscillation and a very broad spectrum.

Coded Excitation Plane Wave Imaging for Shear Wave Motion Detection

PubMed Central

Song, Pengfei; Urban, Matthew W.; Manduca, Armando; Greenleaf, James F.; Chen, Shigao

2015-01-01

Plane wave imaging has greatly advanced the field of shear wave elastography thanks to its ultrafast imaging frame rate and the large field-of-view (FOV). However, plane wave imaging also has decreased penetration due to lack of transmit focusing, which makes it challenging to use plane waves for shear wave detection in deep tissues and in obese patients. This study investigated the feasibility of implementing coded excitation in plane wave imaging for shear wave detection, with the hypothesis that coded ultrasound signals can provide superior detection penetration and shear wave signal-to-noise-ratio (SNR) compared to conventional ultrasound signals. Both phase encoding (Barker code) and frequency encoding (chirp code) methods were studied. A first phantom experiment showed an approximate penetration gain of 2-4 cm for the coded pulses. Two subsequent phantom studies showed that all coded pulses outperformed the conventional short imaging pulse by providing superior sensitivity to small motion and robustness to weak ultrasound signals. Finally, an in vivo liver case study on an obese subject (Body Mass Index = 40) demonstrated the feasibility of using the proposed method for in vivo applications, and showed that all coded pulses could provide higher SNR shear wave signals than the conventional short pulse. These findings indicate that by using coded excitation shear wave detection, one can benefit from the ultrafast imaging frame rate and large FOV provided by plane wave imaging while preserving good penetration and shear wave signal quality, which is essential for obtaining robust shear elasticity measurements of tissue. PMID:26168181

The Use Of Double Pulsed Holography For On-Site Vibration Analysis

NASA Astrophysics Data System (ADS)

Tyrer, John R.

1985-06-01

A description is given of a laser system used to produce interferograms of a large centrifugal compressor, powered by an industrial gas turbine engine with a dominant system response at 168Hz. The results demonstrate a travelling wave generated within the feed pipe to the compressor. Finally the description of a potential real time double pulse systeu is presented.

Mathematics of pulsed vocalizations with application to killer whale biphonation.

PubMed

Brown, Judith C

2008-05-01

Formulas for the spectra of pulsed vocalizations for both the continuous and discrete cases are rigorously derived from basic formulas for Fourier analysis, a topic discussed qualitatively in Watkins' classic paper on "the harmonic interval" ["The harmonic interval: Fact or artifact in spectral analysis of pulse trains," in Marine Bioacoustics 2, edited by W. N. Tavogla (Pergamon, New York, 1967), pp. 15-43]. These formulas are summarized in a table for easy reference, along with most of the corresponding graphs. The case of a "pulse tone" is shown to involve multiplication of two temporal wave forms, corresponding to convolution in the frequency domain. This operation is discussed in detail and shown to be equivalent to a simpler approach using a trigonometric formula giving sum and difference frequencies. The presence of a dc component in the temporal wave form, which implies physically that there is a net positive pressure at the source, is discussed, and examples of the corresponding spectra are calculated and shown graphically. These have application to biphonation (two source signals) observed for some killer whale calls and implications for a source mechanism. A MATLAB program for synthesis of a similar signal is discussed and made available online.

Pulse based sensor networking using mechanical waves through metal substrates

NASA Astrophysics Data System (ADS)

Lorenz, S.; Dong, B.; Huo, Q.; Tomlinson, W. J.; Biswas, S.

2013-05-01

This paper presents a novel wireless sensor networking technique using ultrasonic signal as the carrier wave for binary data exchange. Using the properties of lamb wave propagation through metal substrates, the proposed network structure can be used for runtime transport of structural fault information to ultrasound access points. Primary applications of the proposed sensor networking technique will include conveying fault information on an aircraft wing or on a bridge to an ultrasonic access point using ultrasonic wave through the structure itself (i.e. wing or bridge). Once a fault event has been detected, a mechanical pulse is forwarded to the access node using shortest path multi-hop ultrasonic pulse routing. The advantages of mechanical waves over traditional radio transmission using pulses are the following: First, unlike radio frequency, surface acoustic waves are not detectable outside the medium, which increases the inherent security for sensitive environments in respect to tapping. Second, event detection can be represented by the injection of a single mechanical pulse at a specific temporal position, whereas radio messages usually take several bits. The contributions of this paper are: 1) Development of a transceiver for transmitting/receiving ultrasound pulses with a pulse loss rate below 2·10-5 and false positive rate with an upper bound of 2·10-4. 2) A novel one-hop distance estimation based on the properties of lamb wave propagation with an accuracy of above 80%. 3) Implementation of a wireless sensor network using mechanical wave propagation for event detection on a 2024 aluminum alloy commonly used for aircraft skin construction.

978-nm square-wave in an all-fiber single-mode ytterbium-doped fiber laser

NASA Astrophysics Data System (ADS)

Li, Shujie; Xu, Lixin; Gu, Chun

2018-01-01

A 978 nm single mode passively mode-locked all-fiber laser delivering square-wave pulses was demonstrated using a figure-8 cavity and a 75 cm commercial double-clad ytterbium-doped fiber. We found the three-level system near 978 nm was able to operate efficiently under clad pumping, simultaneously oscillation around 1030 nm well inhibited. The optimized nonlinear amplifying loop mirror made the mode locking stable and performed the square-pulses shaping. To the best of our knowledge, it is the first time to report the square-wave pulse fiber laser operating at 980 nm. The spectral width of the 978 mode-locked square pulses was about 4 nm, far greater than that of the mode-locked square pulses around 1060 nm reported before, which would be helpful to deeply understand the various square-wave pulses' natures and forming mechanisms. Compared with modulated single-mode or multimode 980 nm LDs, this kind of 980 nm square-wave sources having higher brightness, more steeper rising and falling edge and shorter pulse width, might have potential applications in pumping nanosecond ytterbium or erbium fiber lasers and amplifiers.

Optical generation of millimeter-wave pulses using a fiber Bragg grating in a fiber-optics system.

PubMed

Ye, Qing; Qu, Ronghui; Fang, Zujie

2007-04-10

A scheme is proposed to transform an optical pulse into a millimeter-wave frequency modulation pulse by using a weak fiber Bragg grating (FBG) in a fiber-optics system. The Fourier transformation method is used to obtain the required spectrum response function of the FBG for the Gaussian pulse, soliton pulse, and Lorenz shape pulse. On the condition of the first-order Born approximation of the weak fiber grating, the relation of the refractive index distribution and the spectrum response function of the FBG satisfies the Fourier transformation, and the corresponding refractive index distribution forms are obtained for single-frequency modulation and linear-frequency modulation millimeter-wave pulse generation. The performances of the designed fiber gratings are also studied by a numerical simulation method for a supershort pulse transmission.

Optical Precursor with Four-Wave Mixing and Storage Based on a Cold-Atom Ensemble

NASA Astrophysics Data System (ADS)

Ding, Dong-Sheng; Jiang, Yun Kun; Zhang, Wei; Zhou, Zhi-Yuan; Shi, Bao-Sen; Guo, Guang-Can

2015-03-01

We observed optical precursors in four-wave mixing based on a cold-atom gas. Optical precursors appear at the edges of pulses of the generated optical field, and propagate through the atomic medium without absorption. Theoretical analysis suggests that these precursors correspond to high-frequency components of the signal pulse, which means the atoms cannot respond quickly to rapid changes in the electromagnetic field. In contrast, the low-frequency signal components are absorbed by the atoms during transmission. We also showed experimentally that the backward precursor can be stored using a Raman transition of the atomic ensemble and retrieved later.

Non-invasive measurement of pulse wave velocity using transputer-based analysis of Doppler flow audio signals.

PubMed

Stewart, W R; Ramsey, M W; Jones, C J

1994-08-01

A system for the measurement of arterial pulse wave velocity is described. A personal computer (PC) plug-in transputer board is used to process the audio signals from two pocket Doppler ultrasound units. The transputer is used to provide a set of bandpass digital filters on two channels. The times of excursion of power through thresholds in each filter are recorded and used to estimate the onset of systolic flow. The system does not require an additional spectrum analyser and can work in real time. The transputer architecture provides for easy integration into any wider physiological measurement system.

Effect of black tea consumption on radial blood pulse spectrum and cognitive health.

PubMed

Chang, Chi-Wei; Wang, Sheng-Hung; Jan, Ming-Yie; Wang, Wei-Kung

2017-04-01

Black tea consumption has been proven to improve endothelial function and to lower the risk of stroke and cognitive impairment. Several effects of black tea on cardiovascular system had been surveyed. However, the black tea effect on pressure pulse spectrum remains unknown. The study was aimed to investigate the influence of black tea on radial blood pressure and Pulse Spectrum. Fourteen healthy subjects received water and single doses of black tea (0.05g/Kg) in separate weeks. The radial blood pressure and pulse wave were measured and the pressure pulses were evaluated using harmonic analysis. This report confirmed that black tea consumption (dose=0.05g/Kg) significantly increased third, fifth, (P<0.1), sixth, seventh, and eighth harmonics (p<0.05) of radial pressure wave comparing to water control. We proposed that black tea may increase cerebral blood flow (CBF), which was deduced from the results and from the conclusions of previous studies. The results also showed that the harmonic components of pressure pulse could be the vascular kinetic index that assessed the hemodynamic status in each time frame before and after consumption of black tea. Copyright © 2017 Elsevier Ltd. All rights reserved.

Excitation of plasma waves by nonlinear currents induced by a high-frequency electromagnetic pulse

NASA Astrophysics Data System (ADS)

Grishkov, V. E.; Uryupin, S. A.

2017-03-01

Excitation of plasma waves by nonlinear currents induced by a high-frequency electromagnetic pulse is analyzed within the kinetic approach. It is shown that the most efficient source of plasma waves is the nonlinear current arising due to the gradient of the energy density of the high-frequency field. Generation of plasma waves by the drag current is usually less efficient but not negligibly small at relatively high frequencies of electron-ion collisions. The influence of electron collisions on the excitation of plasma waves by pulses of different duration is described quantitatively.

Theory of spin and lattice wave dynamics excited by focused laser pulses

NASA Astrophysics Data System (ADS)

Shen, Ka; Bauer, Gerrit E. W.

2018-06-01

We develop a theory of spin wave dynamics excited by ultrafast focused laser pulses in a magnetic film. We take into account both the volume and surface spin wave modes in the presence of applied, dipolar and magnetic anisotropy fields and include the dependence on laser spot exposure size and magnetic damping. We show that the sound waves generated by local heating by an ultrafast focused laser pulse can excite a wide spectrum of spin waves (on top of a dominant magnon–phonon contribution). Good agreement with recent experiments supports the validity of the model.

Excitation of plasma waves by nonlinear currents induced by a high-frequency electromagnetic pulse

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grishkov, V. E.; Uryupin, S. A., E-mail: uryupin@sci.lebedev.ru

Excitation of plasma waves by nonlinear currents induced by a high-frequency electromagnetic pulse is analyzed within the kinetic approach. It is shown that the most efficient source of plasma waves is the nonlinear current arising due to the gradient of the energy density of the high-frequency field. Generation of plasma waves by the drag current is usually less efficient but not negligibly small at relatively high frequencies of electron–ion collisions. The influence of electron collisions on the excitation of plasma waves by pulses of different duration is described quantitatively.

Comparison of an oscillometric method with cardiac magnetic resonance for the analysis of aortic pulse wave velocity.

PubMed

Feistritzer, Hans-Josef; Reinstadler, Sebastian J; Klug, Gert; Kremser, Christian; Seidner, Benjamin; Esterhammer, Regina; Schocke, Michael F; Franz, Wolfgang-Michael; Metzler, Bernhard

2015-01-01

Pulse wave velocity (PWV) is the proposed gold-standard for the assessment of aortic elastic properties. The aim of this study was to compare aortic PWV determined by a recently developed oscillometric device with cardiac magnetic resonance imaging (CMR). PWV was assessed in 40 volunteers with two different methods. The oscillometric method (PWVOSC) is based on a transfer function from the brachial pressure waves determined by oscillometric blood pressure measurements with a common cuff (Mobil-O-Graph, I.E.M. Stolberg, Germany). CMR was used to determine aortic PWVCMR with the use of the transit time method based on phase-contrast imaging at the level of the ascending and abdominal aorta on a clinical 1.5 Tesla scanner (Siemens, Erlangen, Germany). The median age of the study population was 34 years (IQR: 24-55 years, 11 females). A very strong correlation was found between PWVOSC and PWVCMR (r = 0.859, p < 0.001). Mean PWVOSC was 6.7 ± 1.8 m/s and mean PWVCMR was 6.1 ± 1.8 m/s (p < 0.001). Analysis of agreement between the two measurements using Bland-Altman method showed a bias of 0.57 m/s (upper and lower limit of agreement: 2.49 m/s and -1.34 m/s). The corresponding coefficient of variation between both measurements was 15%. Aortic pulse wave velocity assessed by transformation of the brachial pressure waveform showed an acceptable agreement with the CMR-derived transit time method.

Generation of ultra-wideband triplet pulses based on four-wave mixing and phase-to-intensity modulation conversion.

PubMed

Li, Wei; Wang, Li Xian; Hofmann, Werner; Zhu, Ning Hua; Bimberg, Dieter

2012-08-27

We propose and demonstrate a novel scheme to generate ultra-wideband (UWB) triplet pulses based on four-wave mixing and phase-to-intensity modulation conversion. First a phase-modulated Gaussian doublet pulse is generated by four-wave mixing in a highly nonlinear fiber. Then an UWB triplet pulse is generated by generating the first-order derivative of the phase-modulated Gaussian doublet pulse using an optical filter serving as a frequency discriminator. By locating the optical signal at the linear slope of the optical filter, the phase modulated Gaussian doublet pulse is converted to an intensity-modulated UWB triplet pulse which well satisfies the Federal Communications Commission spectral mask requirements, even in the extremely power-restricted global positioning system band.

Extension of harmonic cutoff in a multicycle chirped pulse combined with a chirp-free pulse

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xu Junjie; Zeng Bin; Yu Yongli

2010-11-15

We demonstrate high-order harmonic generation in a wave form synthesized by a multicycle 800-nm chirped laser pulse and a chirp-free laser pulse. Compared with the case of using only a chirped pulse, both the harmonic cutoff and the extreme ultraviolet supercontinuum can be extended when a weak chirp-free pulse is combined with the chirped pulse. When chirp-free pulse intensity grows, the cutoff energy and bandwidth of the supercontinuum grow as well. It is found that the broad supercontinuum can be achieved for a driving pulse with long duration even though the driving pulse reaches 10 optical cycles. An isolated attosecondmore » pulse with duration of about 59 as is obtained, and after appropriate phase compensation with a duration of about 11 as. In addition, by performing time-frequency analyses and the classical trajectory simulation, the difference in supercontinuum generation between the preceding wave form and a similar wave form synthesized by an 800-nm fundamental pulse and a 1600-nm subharmonic pulse is investigated.« less

Radiation from long pulse train electron beams in space plasmas

NASA Technical Reports Server (NTRS)

Harker, K. J.; Banks, P. M.

1985-01-01

A previous study of electromagnetic radiation from a finite train of electron pulses is extended to an infinite train of such pulses. The electrons are assumed to follow an idealized helical path through a space plasma in such a manner as to retain their respective position within the beam. This leads to radiation by coherent spontaneous emission. The waves of interest in this region are the whistler slow (compressional) and fast (torsional) Alfven waves. Although a general theory is developed, analysis is then restricted to two approximations, the short and long electron beam. Formulas for the radiation per unit solid angle from the short beam are presented as a function of both propagation and ray angles, electron beam pulse width and separation and beam current, voltage, and pitch angle. Similar formulas for the total power radiated from the long beam are derived as a function of frequency, propagation angle, and ray angle. Predictions of the power radiated are presented for representative examples as determined by the long beam theory.

Pulse wave imaging in normal, hypertensive and aneurysmal human aortas in vivo: a feasibility study

NASA Astrophysics Data System (ADS)

Li, Ronny X.; Luo, Jianwen; Balaram, Sandhya K.; Chaudhry, Farooq A.; Shahmirzadi, Danial; Konofagou, Elisa E.

2013-07-01

Arterial stiffness is a well-established biomarker for cardiovascular risk, especially in the case of hypertension. The progressive stages of an abdominal aortic aneurysm (AAA) have also been associated with varying arterial stiffness. Pulse wave imaging (PWI) is a noninvasive, ultrasound imaging-based technique that uses the pulse wave-induced arterial wall motion to map the propagation of the pulse wave and measure the regional pulse wave velocity (PWV) as an index of arterial stiffness. In this study, the clinical feasibility of PWI was evaluated in normal, hypertensive, and aneurysmal human aortas. Radiofrequency-based speckle tracking was used to estimate the pulse wave-induced displacements in the abdominal aortic walls of normal (N = 15, mean age 32.5 ± 10.2 years), hypertensive (N = 13, mean age 60.8 ± 15.8 years), and aneurysmal (N = 5, mean age 71.6 ± 11.8 years) human subjects. Linear regression of the spatio-temporal variation of the displacement waveform in the anterior aortic wall over a single cardiac cycle yielded the slope as the PWV and the coefficient of determination r2 as an approximate measure of the pulse wave propagation uniformity. The aortic PWV measurements in all normal, hypertensive, and AAA subjects were 6.03 ± 1.68, 6.69 ± 2.80, and 10.54 ± 6.52 m s-1, respectively. There was no significant difference (p = 0.15) between the PWVs of the normal and hypertensive subjects while the PWVs of the AAA subjects were significantly higher (p < 0.001) compared to those of the other two groups. Also, the average r2 in the AAA subjects was significantly lower (p < 0.001) than that in the normal and hypertensive subjects. These preliminary results suggest that the regional PWV and the pulse wave propagation uniformity (r2) obtained using PWI, in addition to the PWI images and spatio-temporal maps that provide qualitative visualization of the pulse wave, may potentially provide valuable information for the clinical characterization of aneurysms and other vascular pathologies that regionally alter the arterial wall mechanics.

Pulse Wave Amplitude Drops during Sleep are Reliable Surrogate Markers of Changes in Cortical Activity

PubMed Central

Delessert, Alexandre; Espa, Fabrice; Rossetti, Andrea; Lavigne, Gilles; Tafti, Mehdi; Heinzer, Raphael

2010-01-01

Background: During sleep, sudden drops in pulse wave amplitude (PWA) measured by pulse oximetry are commonly associated with simultaneous arousals and are thought to result from autonomic vasoconstriction. In the present study, we determine whether PWA drops were associated with changes in cortical activity as determined by EEG spectral analysis. Methods: A 20% decrease in PWA was chosen as a minimum for a drop. A total of 1085 PWA drops from 10 consecutive sleep recordings were analyzed. EEG spectral analysis was performed over 5 consecutive epochs of 5 seconds: 2 before, 1 during, and 2 after the PWA drop. EEG spectral analysis was performed over delta, theta, alpha, sigma, and beta frequency bands. Within each frequency band, power density was compared across the five 5-sec epochs. Presence or absence of visually scored EEG arousals were adjudicated by an investigator blinded to the PWA signal and considered associated with PWA drop if concomitant. Results: A significant increase in EEG power density in all EEG frequency bands was found during PWA drops (P < 0.001) compared to before and after drop. Even in the absence of visually scored arousals, PWA drops were associated with a significant increase in EEG power density (P < 0.001) in most frequency bands. Conclusions: Drops in PWA are associated with a significant increase in EEG power density, suggesting that these events can be used as a surrogate for changes in cortical activity during sleep. This approach may prove of value in scoring respiratory events on limited-channel (type III) portable monitors. Citation: Delessert A; Espa F; Rossetti A; Lavigne G; Tafti M; Heinzer R. Pulse wave amplitude drops during sleep are reliable surrogate markers of changes in cortical activity. SLEEP 2010;33(12):1687-1692. PMID:21120131

Increased aortic wave reflection contributes to higher systolic blood pressure in adolescents born preterm.

PubMed

Kowalski, Remi R; Beare, Richard; Mynard, Jonathan P; Cheong, Jeanie L Y; Doyle, Lex W; Smolich, Joseph J; Cheung, Michael M H

2018-03-29

To evaluate the wave reflection characteristics in the aortic arch and common carotid artery of ex-preterm adolescents and assess their relationship to central blood pressure in a cohort followed prospectively since birth. Central blood pressures, pulse wave velocity, augmentation index, microvascular reactive hyperemia, arterial distensibility, compliance and stiffness index, and also aortic and carotid wave intensity were measured in 18-year-olds born extremely preterm at below 28 weeks' gestation (n = 76) and term-born controls (n = 42). Compared with controls, ex-preterm adolescents had higher central systolic (111 ± 11 vs. 105 ± 10 mmHg; P < 0.001) and diastolic blood pressures (73 ± 7 vs. 67 ± 7 mmHg; P < 0.001). Although conventional measures of arterial function and biomechanics such as pulse wave velocity and augmentation index were no different between groups, wave intensity analysis revealed elevated backward compression wave area (-0.39 ± 0.21 vs. -0.29 ± 0.17 W/m/s × 10; P = 0.03), backward compression wave pressure change (9.0 ± 3.5 vs. 6.6 ± 2.5 mmHg; P = 0.001) and reflection index (0.44 ± 0.15 vs. 0.32 ± 0.08; P < 0.001) in the aorta of ex-preterm adolescents compared with controls. These changes were less pronounced in the carotid artery. On multivariable analysis, forward and backward compression wave areas were the only biomechanical variables associated with central systolic pressure. Ex-preterm adolescents demonstrate elevated wave reflection indices in the aortic arch, which correlate with central systolic pressure. Wave intensity analysis may provide a sensitive novel marker of evolving vascular dysfunction in ex-preterm survivors.

Generation of multicolor vacuum ultraviolet pulses through four-wave sum-frequency mixing in argon

NASA Astrophysics Data System (ADS)

Shi, Liping; Li, Wenxue; Zhou, Hui; Wang, Di; Ding, Liang'en; Zeng, Heping

2013-11-01

We demonstrate efficient generation of multicolor vacuum ultraviolet pulses with excellent mode quality through χ(3)-based four-wave sum-frequency mixing and third-order harmonic generation of 400- and 267-nm femtosecond laser pulses in argon gas. The χ(3)-based nonlinear optical processes were optimized with appropriate control of gas pressure and group velocity delay between the driving pulses. Furthermore, the pulse breakup effects were observed for tightly focused ultraviolet pulses.

Comparison of acoustic shock waves generated by micro and nanosecond lasers for a smart laser surgery system

NASA Astrophysics Data System (ADS)

Nguendon Kenhagho, Hervé K.; Rauter, Georg; Guzman, Raphael; C. Cattin, Philippe; Zam, Azhar

2018-02-01

Characterization of acoustic shock wave will guarantee efficient tissue differentiation as feedback to reduce the probability of undesirable damaging (i.e. cutting) of tissues in laser surgery applications. We ablated hard (bone) and soft (muscle) tissues using a nanosecond pulsed Nd:YAG laser at 532 nm and a microsecond pulsed Er:YAG laser at 2.94 μm. When the intense short ns-pulsed laser is applied to material, the energy gain causes locally a plasma at the ablated spot that expands and propagates as an acoustic shock wave with a rarefaction wave behind the shock front. However, when using a μs-pulsed Er:YAG laser for material ablation, the acoustic shock wave is generated during the explosion of the ablated material. We measured and compared the emitted acoustic shock wave generated by a ns-pulsed Nd:YAG laser and a μs-pulsed Er:YAG laser measured by a calibrated microphone. As the acoustic shock wave attenuates as it propagates through air, the distance between ablation spots and a calibrated microphone was at 5 cm. We present the measurements on the propagation characteristics of the laser generated acoustic shock wave by measuring the arrival time-of-flight with a calibrated microphone and the energy-dependent evolution of acoustic parameters such as peak-topeak pressure, the ratio of the peak-to-peak pressures for the laser induced breakdown in air, the ablated muscle and the bone, and the spectral energy.

Amplification of pressure waves in laser-assisted endodontics with synchronized delivery of Er:YAG laser pulses.

PubMed

Lukač, Nejc; Jezeršek, Matija

2018-05-01

When attempting to clean surfaces of dental root canals with laser-induced cavitation bubbles, the resulting cavitation oscillations are significantly prolonged due to friction on the cavity walls and other factors. Consequently, the collapses are less intense and the shock waves that are usually emitted following a bubble's collapse are diminished or not present at all. A new technique of synchronized laser-pulse delivery intended to enhance the emission of shock waves from collapsed bubbles in fluid-filled endodontic canals is reported. A laser beam deflection probe, a high-speed camera, and shadow photography were used to characterize the induced photoacoustic phenomena during synchronized delivery of Er:YAG laser pulses in a confined volume of water. A shock wave enhancing technique was employed which consists of delivering a second laser pulse at a delay with regard to the first cavitation bubble-forming laser pulse. Influence of the delay between the first and second laser pulses on the generation of pressure and shock waves during the first bubble's collapse was measured for different laser pulse energies and cavity volumes. Results show that the optimal delay between the two laser pulses is strongly correlated with the cavitation bubble's oscillation period. Under optimal synchronization conditions, the growth of the second cavitation bubble was observed to accelerate the collapse of the first cavitation bubble, leading to a violent collapse, during which shock waves are emitted. Additionally, shock waves created by the accelerated collapse of the primary cavitation bubble and as well of the accompanying smaller secondary bubbles near the cavity walls were observed. The reported phenomena may have applications in improved laser cleaning of surfaces during laser-assisted dental root canal treatments.

A critical survey of wave propagation and impact in composite materials

NASA Technical Reports Server (NTRS)

Moon, F. C.

1973-01-01

A review of the field of stress waves in composite materials is presented covering the period up to December 1972. The major properties of waves in composites are discussed and a summary is made of the major experimental results in this field. Various theoretical models for analysis of wave propagation in laminated, fiber and particle reinforced composites are surveyed. The anisotropic, dispersive and dissipative properties of stress pulses and shock waves in such materials are reviewed. A review of the behavior of composites under impact loading is presented along with the application of wave propagation concepts to the determination of impact stresses in composite plates.

Self-reflection of extremely short light pulses in nonlinear optical waveguides

NASA Astrophysics Data System (ADS)

Kurasov, Alexander E.; Kozlov, Sergei A.

2004-07-01

An equation describing the generation of reflected radiation during the propagation of high-intensity extremely short pulses in a nonlinear optical waveguide is derived. The phenomena taking place during the strong self-inducted changes of the temporal structure of the forward wave are studied. It is shown that the duration of the backward pulse is much greater than the duration of the forward pulse and that the main part of the energy of the backward wave is carried by lower frequencies than the central frequency of the forward wave.

Effect of Shock Waves Generated by Pulsed Electric Discharges in Water on Yeast Cells and Virus Particles

NASA Astrophysics Data System (ADS)

Girdyuk, A. E.; Gorshkov, A. N.; Egorov, V. V.; Kolikov, V. A.; Snetov, V. N.; Shneerson, G. A.

2018-02-01

The aim of this study is to determine the optimal parameters of the electric pulses and shock waves generated by them for the soft destruction of the virus and yeast envelopes with no changes in the structure of antigenic surface albumin and in the cell morphology in order to use them to produce antivirus vaccines and in biotechnology. The pulse electric discharges in water have been studied for different values of amplitude, pulse duration and the rate of the rise in the current. A mathematical model has been developed to estimate the optimal parameters of pulsed electric charges and shock waves for the complete destruction of the yeast cell envelopes and virus particles at a minimum of pulses.

Sequentially pulsed traveling wave accelerator

DOEpatents

Caporaso, George J [Livermore, CA; Nelson, Scott D [Patterson, CA; Poole, Brian R [Tracy, CA

2009-08-18

A sequentially pulsed traveling wave compact accelerator having two or more pulse forming lines each with a switch for producing a short acceleration pulse along a short length of a beam tube, and a trigger mechanism for sequentially triggering the switches so that a traveling axial electric field is produced along the beam tube in synchronism with an axially traversing pulsed beam of charged particles to serially impart energy to the particle beam.

Contributions of aortic pulse wave velocity and backward wave pressure to variations in left ventricular mass are independent of each other.

PubMed

Bello, Hamza; Norton, Gavin R; Ballim, Imraan; Libhaber, Carlos D; Sareli, Pinhas; Woodiwiss, Angela J

2017-05-01

Aortic pulse wave velocity (PWV) and backward waves, as determined from wave separation analysis, predict cardiovascular events beyond brachial blood pressure. However, the extent to which these aortic hemodynamic variables contribute independent of each other is uncertain. In 749 randomly selected participants of African ancestry, we therefore assessed the extent to which relationships between aortic PWV or backward wave pressures (Pb) (and hence central aortic pulse pressure [PPc]) and left ventricular mass index (LVMI) occur independent of each other. Aortic PWV, PPc, forward wave pressure (Pf), and Pb were determined using radial applanation tonometry and SphygmoCor software and LVMI using echocardiography; 44.5% of participants had an increased left ventricular mass indexed to height 1.7 . With adjustments for age, brachial systolic blood pressure or PP, and additional confounders, PPc and Pb, but not Pf, were independently related to LVMI and left ventricular hypertrophy (LVH) in both men and women. However, PWV was independently associated with LVMI in women (partial r = 0.16, P < .001), but not in men (partial r = 0.03), and PWV was independently associated with LVH in women (P < .05), but not in men (P = .07). With PWV and Pb included in the same multivariate regression models, PWV (partial r = 0.14, P < .005) and Pb (partial r = 0.10, P < .05) contributed to a similar extent to variations in LVMI in women. In addition, with PWV and Pb included in the same multivariate regression models, PWV (P < .05) and Pb (P < .02) contributed to LVH in women. In conclusion, aortic PWV and Pb (and hence pulse pressure) although both associated with LVMI and LVH produce effects which are independent of each other. Copyright © 2017 American Society of Hypertension. Published by Elsevier Inc. All rights reserved.

Optical rogue waves generation in a nonlinear metamaterial

NASA Astrophysics Data System (ADS)

Onana Essama, Bedel Giscard; Atangana, Jacques; Biya-Motto, Frederick; Mokhtari, Bouchra; Cherkaoui Eddeqaqi, Noureddine; Kofane, Timoleon Crepin

2014-11-01

We investigate the behavior of electromagnetic wave which propagates in a metamaterial for negative index regime. The optical pulse propagation is described by the nonlinear Schrödinger equation with cubic-quintic nonlinearities, second- and third-order dispersion effects. The behavior obtained for negative index regime is compared to that observed for positive index regime. The characterization of electromagnetic wave uses some pulse parameters obtained analytically and called collective coordinates such as amplitude, temporal position, width, chirp, frequency shift and phase. Six frequency ranges have been pointed out where a numerical evolution of collective coordinates and their stability are studied under a typical example to verify our analysis. It appears that a robust soliton due to a perfect compensation process between second-order dispersion and cubic-nonlinearity is presented at each frequency range for both negative and positive index regimes. Thereafter, the stability of the soliton pulse and physical conditions leading to optical rogue waves generation are discussed at each frequency range for both regimes, when third-order dispersion and quintic-nonlinearity come into play. We have demonstrated that collective coordinates give much useful information on external and internal behavior of rogue events. Firstly, we determine at what distance begins the internal excitation leading to rogue waves. Secondly, what kind of internal modification and how it modifies the system in order to build-up rogue events. These results lead to a best comprehension of the mechanism of rogue waves generation. So, it clearly appears that the rogue wave behavior strongly depends on nonlinearity strength of distortion, frequency and regime considered.

Shear wave pulse compression for dynamic elastography using phase-sensitive optical coherence tomography

NASA Astrophysics Data System (ADS)

Nguyen, Thu-Mai; Song, Shaozhen; Arnal, Bastien; Wong, Emily Y.; Huang, Zhihong; Wang, Ruikang K.; O'Donnell, Matthew

2014-01-01

Assessing the biomechanical properties of soft tissue provides clinically valuable information to supplement conventional structural imaging. In the previous studies, we introduced a dynamic elastography technique based on phase-sensitive optical coherence tomography (PhS-OCT) to characterize submillimetric structures such as skin layers or ocular tissues. Here, we propose to implement a pulse compression technique for shear wave elastography. We performed shear wave pulse compression in tissue-mimicking phantoms. Using a mechanical actuator to generate broadband frequency-modulated vibrations (1 to 5 kHz), induced displacements were detected at an equivalent frame rate of 47 kHz using a PhS-OCT. The recorded signal was digitally compressed to a broadband pulse. Stiffness maps were then reconstructed from spatially localized estimates of the local shear wave speed. We demonstrate that a simple pulse compression scheme can increase shear wave detection signal-to-noise ratio (>12 dB gain) and reduce artifacts in reconstructing stiffness maps of heterogeneous media.

A study of phase explosion of metal using high power Nd:YAG laser ablation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yoh, Jack J.; Lee, H. H.; Choi, J. H.

2007-12-12

The interaction of high-power pulsed-laser beam with metal targets in air from 1.06 {mu}m, 5 ns, 3 J/pulse max, Nd:YAG pulsed laser is investigated together with hydrodynamic theories of laser-supported detonation (LSD) wave and multi-material reactive Euler equations. The high speed blast wave generated by the laser ablation of metal reaches maximum velocity of several thousand meters per second. The apparently similar flow conditions to those of reactive shock wave allow one to apply the equations of motion for energetic materials and to understand the explosive behavior of metal vaporization upon laser ablation. The characteristic time at which planar tomore » spherical wave transition occurs is confirmed at low (20 mJ/pulse) to higher (200 mJ/pulse) beam intensities. The flow structure behind the leading shock wave during the early planar shock state is confirmed by the high-resolution multi-material hydrocode originally developed for shock compression of condensed matter.« less

[Arterial sequelae of pregnancy hypertension. Detection by carotid piezogram].

PubMed

Meyer-Heine, A; Asquer, J C; Lagrue, G

1989-01-01

High blood pressure (HTA) is characterized by elevation of pression, but also by modifications of arterial pulse wave. Carotid piezograms were used to evaluate arterial pulse wave. Diastolic blood pressure is significantly correlated with dicrotic notch pressure. The duration of dicrotic notch is negatively correlated with arterial wall elasticity. Thus by carotid piezogram analysis one can determine the respective participation of arterial wall elasticity, peripheral resistance and cardiac factors in blood pressure elevation. Carotid piezograms were measured in 97 women (mean age 27, 8 y), with previous hypertensive pregnancy and apparently cured (mean blood pressure 122-74 mmHg at time of examination). 25 women only had normal piezogram drawing. Abnormalities similar to that of permanent hypertensive disease were observed in most cases. Dicrotic notch duration was significantly reduced and dicrotic notch pressure enhanced; in 34 women both of these abnormalities were present. In conclusion, among women previously hypertensive during pregnancy, even when blood pressure is returned to normal, abnormalities of arterial pulse wave may be present, suggesting that these women are prone to subsequent permanent hypertension.

Cross-polarized wave generation (XPW) for ultrafast laser pulse characterization and intensity contrast enhancement

NASA Astrophysics Data System (ADS)

Iliev, Marin

Good pulse quality, high peak power and tunable central wavelength are amongst the most desired qualities in modern lasers. The nonlinear effect cross-polarized wave generation (XPW), can be used in ultrafast laser systems to achieve various pulse quality enhancements. The XPW yield depends on the cube of the input intensity and acts as a spatio-temporal filter. It is orthogonally polarized to the input pulse and highly Gaussian. If the input pulse is well compressed, the output spectrum is smoother and broader. These features make XPW an ideal reference signal in pulse characterization techniques. This thesis presents a detailed analysis of the XPW conversion process, and describes novel applications to pulse characterization and high-quality pulse cleaning. An extensive computer model was developed to describe XPW generation via solution of the full coupled non-linear differential equations. The model accounts for dispersion inside the nonlinear crystal and uses split-step Fourier optics beam propagation to simulate the evolution of the electro-magnetic fields of the pump and XPW through free-space and imaging systems. A novel extension to the self-referenced spectral interferometry (SRSI) pulse characterization technique allows the retrieval of the energy and spectral content of the amplified spontaneous emission (ASE) present in ultrashort pulse amplifier systems. A novel double-pass XPW conversion scheme is presented. In it the beam passes through a single XPW crystal (BaF2) and is re-imaged with a curved mirror. The technique resulted in good (˜30%) efficiency without the spatial aberrations commonly seen in another arrangement that uses two crystals in succession. The modeling sheds light on the complicated nonlinear beam dynamics of the double-crystal conversion, including self- and cross-phase modulation, self-focusing, and the effects of, relative on-axis phase-difference, relative beam sizes, and wave-front curvature matching on seeded XPW conversion. Finally, a design is presented for exploiting the clean-up properties of XPW at the output of an optical parametric generation (OPA) setup in conjunction with an extremely compact prism compressor. The prisms material, separation and geometry are designed carefully to work at the correct wavelength of the OPA setup and are extrapolated to accommodate wavelengths, such as 2mum of parametric wave generation.

Kinetic Monte Carlo simulations of travelling pulses and spiral waves in the lattice Lotka-Volterra model.

PubMed

Makeev, Alexei G; Kurkina, Elena S; Kevrekidis, Ioannis G

2012-06-01

Kinetic Monte Carlo simulations are used to study the stochastic two-species Lotka-Volterra model on a square lattice. For certain values of the model parameters, the system constitutes an excitable medium: travelling pulses and rotating spiral waves can be excited. Stable solitary pulses travel with constant (modulo stochastic fluctuations) shape and speed along a periodic lattice. The spiral waves observed persist sometimes for hundreds of rotations, but they are ultimately unstable and break-up (because of fluctuations and interactions between neighboring fronts) giving rise to complex dynamic behavior in which numerous small spiral waves rotate and interact with each other. It is interesting that travelling pulses and spiral waves can be exhibited by the model even for completely immobile species, due to the non-local reaction kinetics.

Statistical analysis of ultrasonic measurements in concrete

NASA Astrophysics Data System (ADS)

Chiang, Chih-Hung; Chen, Po-Chih

2002-05-01

Stress wave techniques such as measurements of ultrasonic pulse velocity are often used to evaluate concrete quality in structures. For proper interpretation of measurement results, the dependence of pulse transit time on the average acoustic impedance and the material homogeneity along the sound path need to be examined. Semi-direct measurement of pulse velocity could be more convenient than through transmission measurement. It is not necessary to assess both sides of concrete floors or walls. A novel measurement scheme is proposed and verified based on statistical analysis. It is shown that Semi-direct measurements are very effective for gathering large amount of pulse velocity data from concrete reference specimens. The variability of measurements is comparable with that reported by American Concrete Institute using either break-off or pullout tests.

Novel Signal Noise Reduction Method through Cluster Analysis, Applied to Photoplethysmography.

PubMed

Waugh, William; Allen, John; Wightman, James; Sims, Andrew J; Beale, Thomas A W

2018-01-01

Physiological signals can often become contaminated by noise from a variety of origins. In this paper, an algorithm is described for the reduction of sporadic noise from a continuous periodic signal. The design can be used where a sample of a periodic signal is required, for example, when an average pulse is needed for pulse wave analysis and characterization. The algorithm is based on cluster analysis for selecting similar repetitions or pulses from a periodic single. This method selects individual pulses without noise, returns a clean pulse signal, and terminates when a sufficiently clean and representative signal is received. The algorithm is designed to be sufficiently compact to be implemented on a microcontroller embedded within a medical device. It has been validated through the removal of noise from an exemplar photoplethysmography (PPG) signal, showing increasing benefit as the noise contamination of the signal increases. The algorithm design is generalised to be applicable for a wide range of physiological (physical) signals.

Standing Waves in an Elastic Spring: A Systematic Study by Video Analysis

NASA Astrophysics Data System (ADS)

Ventura, Daniel Rodrigues; de Carvalho, Paulo Simeão; Dias, Marco Adriano

2017-04-01

The word "wave" is part of the daily language of every student. However, the physical understanding of the concept demands a high level of abstract thought. In physics, waves are oscillating variations of a physical quantity that involve the transfer of energy from one point to another, without displacement of matter. A wave can be formed by an elastic deformation, a variation of pressure, changes in the intensity of electric or magnetic fields, a propagation of a temperature variation, or other disturbances. Moreover, a wave can be categorized as pulsed or periodic. Most importantly, conditions can be set such that waves interfere with one another, resulting in standing waves. These have many applications in technology, although they are not always readily identified and/or understood by all students. In this work, we use a simple setup including a low-cost constant spring, such as a Slinky, and the free software Tracker for video analysis. We show they can be very useful for the teaching of mechanical wave propagation and the analysis of harmonics in standing waves.

Creating Rydberg electron wave packets using terahertz pulses

NASA Astrophysics Data System (ADS)

Bromage, Jake

1999-10-01

In this thesis I present experiments in which we excited classical-limit states of an atom using terahertz pulses. In a classical-limit state, an atom's outer electron is confined to a wave packet that orbits the core along a classical trajectory. Researchers have excited states with classical traits, but wave packets localized in all three dimensions have proved elusive. Theoretical studies have shown such states can be created using terahertz pulses. Using these techniques, we created a linear-orbit wave packet (LOWP), that is three-dimensionally localized and orbits along a line on one side of the atom's core. Terahertz pulses are sub-picosecond bursts of far- infrared radiation. Unlike ultrashort optical pulses, the electric field of terahertz pulses barely completes a single cycle. Our simulations of the atom-pulse interaction show that this electric field profile is critical in determining the quality of the wave packet. To characterize our terahertz pulses, we invented dithered-edge sampling which time- resolves the electric field using a photoconductive receiver and a triggered attenuator. We also studied how pulses are distorted after propagating through metallic structures, and used our findings to design our atomic experiments. We excited wave packets in atomic sodium using a two-step process. First, we used tunable, nanosecond dye lasers to excite an extreme Stark state. Next, we used a terahertz pump pulse to coherently redistribute population among extreme Stark states in neighboring manifolds. Interference between the final states produces a localized, dynamic LOWP. To analyze the LOWP, we ionized it with a stronger terahertz probe pulse, varying the pump-probe delay to map out its motion. We observed two strong LOWP signatures. Changing the static electric field produced small changes (2%) in the orbital period that agreed with our theoretical predictions. Secondly, because the LOWP scatters off the core, the pump-probe signal depended on the direction of the kick the LOWP received from the robe pulse. These observations, combined with our detailed simulations that used sodium parameters and the actual shape of the terahertz pulse, lead us to conclude that we excited a LOWP.

Constant frequency pulsed phase-locked-loop instrument for measurement of ultrasonic velocity

NASA Technical Reports Server (NTRS)

Yost, William T.; Cantrell, John H.; Kushnick, Peter W.

1991-01-01

A new instrument based on a constant-frequency pulsed phase-locked-loop (CFPPLL) concept has been developed to accurately measure the ultrasonic wave velocity in liquids and changes in ultrasonic wave velocity in solids and liquids. An analysis of the system shows that it is immune to many of the frequency-dependent effects that plague other techniques. Measurements of the sound velocity in ultrapure water are used to confirm the analysis. The results are in excellent agreement with values from the literature, and establish that the CFPPLL provides a reliable, accurate way to measure velocities, as well as for monitoring small changes in velocity without the sensitivity to frequency-dependent phase shifts common to other measurement systems. The estimated sensitivity to phase changes is better than a few parts in 10 to the 7th.

Maternal arterial elasticity in the first trimester as a predictor of birthweight.

PubMed

O'Connor, Clare; O'Higgins, Amy; Segurado, Ricardo; Turner, Michael J; Stuart, Bernard; Kennelly, Máireád M

2016-07-01

The early detection of foetal growth restriction and macrosomia is an important goal of modern obstetric care. Aberrant foetal growth is an important cause of perinatal morbidity and mortality. Current modalities for detecting the abnormal foetal growth are often inadequate. Pulse wave analysis using applanation tonometry is a simple and non-invasive test that provides information about the cardiovascular system. Arterial elasticity has previously been implicated in the pathophysiology of pre-eclampsia and cardiovascular disease. Our study examined the relationship between maternal arterial elasticity and birthweight by using pulse wave analysis. We discovered that increased large artery elasticity predicted a larger baby at birth. Large artery elasticity therefore has the potential to act as a useful screening tool which may help in the prediction of women who are at risk of aberrant foetal growth.

Assessment of macrovascular endothelial function using pulse wave analysis and its association with microvascular reactivity in healthy subjects.

PubMed

Ibrahim, N N I N; Rasool, A H G

2017-08-01

Pulse wave analysis (PWA) and laser Doppler fluximetry (LDF) are non-invasive methods of assessing macrovascular endothelial function and microvascular reactivity respectively. The aim of this study was to assess the correlation between macrovascular endothelial function assessed by PWA and microvascular reactivity assessed by LDF. 297 healthy and non-smoking subjects (159 females, mean age (±SD) 23.56 ± 4.54 years) underwent microvascular reactivity assessment using LDF followed by macrovascular endothelial function assessments using PWA. Pearson's correlation showed no correlation between macrovascular endothelial function and microvascular reactivity (r = -0.10, P = 0.12). There was no significant correlation between macrovascular endothelial function assessed by PWA and microvascular reactivity assessed by LDF in healthy subjects. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Ozone formation behind pulsed-laser-generated blast waves in oxygen

NASA Astrophysics Data System (ADS)

Stricker, J.; Parker, J. G.

1984-12-01

The formation of ozone behind blast waves in oxygen generated by a pulsed laser has been investigated both experimentally and theoretically, over cell pressure range of 0.68-27 atm. Ozone buildup formed by successive pulses was monitored by recording UV absorption at 2540 Å. It was found that, as the number of pulses increase, the rate of ozone formation decreased until finally an equilibrium concentration was reached. This equilibrium magnitude was determined by the condition that the number of ozone molecules produced by the wave equals the number decomposed by the same wave. The decomposition and formation of O3 during a single pulse were monitored by time-resolved UV absorption measurements. In order to provide a fundamental basis for interpretation of the mechanism of ozone formation, a mathematical model was developed. Although qualitatively measurements and theory agree, the data, mainly on the number of O3 molecules produced per pulse, is in significant disagreement. Several possible explanations of this discrepancy are given.

Novel application of parameters in waveform contour analysis for assessing arterial stiffness in aged and atherosclerotic subjects.

PubMed

Wu, Hsien-Tsai; Liu, Cyuan-Cin; Lin, Po-Hsun; Chung, Hui-Ming; Liu, Ming-Chien; Yip, Hon-Kan; Liu, An-Bang; Sun, Cheuk-Kwan

2010-11-01

Although contour analysis of pulse waves has been proposed as a non-invasive means in assessing arterial stiffness in atherosclerosis, accurate determination of the conventional parameters is usually precluded by distorted waveforms in the aged and atherosclerotic objects. We aimed at testing reliable indices in these patient populations. Digital volume pulse (DVP) curve was obtained from 428 subjects recruited from a health screening program at a single medical center from January 2007 to July 2008. Demographic data, blood pressure, and conventional parameters for contour analysis including pulse wave velocity (PWV), crest time (CT), stiffness index (SI), and reflection index (RI) were recorded. Two indices including normalized crest time (NCT) and crest time ratio (CTR) were also analysed and compared with the known parameters. Though ambiguity of dicrotic notch precluded an accurate determination of the two key conventional parameters for assessing arterial stiffness (i.e. SI and RI), NCT and CTR were unaffected because the sum of CT and T(DVP) (i.e. the duration between the systolic and diastolic peak) tended to remain constant. NCT and CTR also correlated significantly with age, systolic and diastolic blood pressure, PWV, SI and RI (all P<0.01). NCT and CTR not only showed significant positive correlations with the conventional parameters for assessment of atherosclerosis (i.e. SI, RI, and PWV), but they also are of particular value in assessing degree of arterial stiffness in subjects with indiscernible peak of diastolic wave that precludes the use of conventional parameters in waveform contour analysis. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

Evolution of the frequency chirp of Gaussian pulses and beams when passing through a pulse compressor.

PubMed

Li, Derong; Lv, Xiaohua; Bowlan, Pamela; Du, Rui; Zeng, Shaoqun; Luo, Qingming

2009-09-14

The evolution of the frequency chirp of a laser pulse inside a classical pulse compressor is very different for plane waves and Gaussian beams, although after propagating through the last (4th) dispersive element, the two models give the same results. In this paper, we have analyzed the evolution of the frequency chirp of Gaussian pulses and beams using a method which directly obtains the spectral phase acquired by the compressor. We found the spatiotemporal couplings in the phase to be the fundamental reason for the difference in the frequency chirp acquired by a Gaussian beam and a plane wave. When the Gaussian beam propagates, an additional frequency chirp will be introduced if any spatiotemporal couplings (i.e. angular dispersion, spatial chirp or pulse front tilt) are present. However, if there are no couplings present, the chirp of the Gaussian beam is the same as that of a plane wave. When the Gaussian beam is well collimated, the introduced frequency chirp predicted by the plane wave and Gaussian beam models are in closer agreement. This work improves our understanding of pulse compressors and should be helpful for optimizing dispersion compensation schemes in many applications of femtosecond laser pulses.

Ballistic pulse propagation in quantum wire waveguides: Toward localization and control of electron wave packets in space and time

NASA Astrophysics Data System (ADS)

Hayata, K.; Tsuji, Y.; Koshiba, M.

1992-10-01

A theoretical formulation of electron pulse propagation in quantum wire structures with mesoscopic scale cross sections is presented, assuming quantum ballistic transport of electron wave packets over a certain characteristic length. As typical mesoscopic structures for realizing coherent electron transmission, two traveling-wave configurations are considered: straight quantum wire waveguides and quantum wire bend structures (quantum whispering galleries). To estimate temporal features of the pulse during propagation, the walk off, the dispersion, and the pulse coherence lengths are defined as useful characteristic lengths. Numerical results are shown for ultrashort pulse propagation through rectangular wire waveguides. Effects due to an external electric field are discussed as well.

Ambulatory (24 h) blood pressure and arterial stiffness measurement in Marfan syndrome patients: a case control feasibility and pilot study.

PubMed

Hillebrand, Matthias; Nouri, Ghazaleh; Hametner, Bernhard; Parragh, Stephanie; Köster, Jelena; Mortensen, Kai; Schwarz, Achim; von Kodolitsch, Yskert; Wassertheurer, Siegfried

2016-05-06

The aim of this work is the investigation of measures of ambulatory brachial and aortic blood pressure and indices of arterial stiffness and aortic wave reflection in Marfan patients. A case-control study was conducted including patients with diagnosed Marfan syndrome following Ghent2 nosology and healthy controls matched for sex, age and daytime brachial systolic blood pressure. For each subject a 24 h ambulatory blood pressure and 24 h pulse wave analysis measurement was performed. All parameters showed a circadian pattern whereby pressure dipping was more pronounced in Marfan patients. During daytime only Marfan patients with aortic root surgery showed increased pulse wave velocity. In contrast, various nighttime measurements, wave reflection determinants and circadian patterns showed a significant difference. The findings of our study provide evidence that ambulatory measurement of arterial stiffness parameters is feasible and that these determinants are significantly different in Marfan syndrome patients compared to controls in particular at nighttime. Further investigation is therefore indicated.

Laboratory Model of the Cardiovascular System for Experimental Demonstration of Pulse Wave Propagation

ERIC Educational Resources Information Center

Stojadinovic, Bojana; Nestorovic, Zorica; Djuric, Biljana; Tenne, Tamar; Zikich, Dragoslav; Žikic, Dejan

2017-01-01

The velocity by which a disturbance moves through the medium is the wave velocity. Pulse wave velocity is among the key parameters in hemodynamics. Investigation of wave propagation through the fluid-filled elastic tube has a great importance for the proper biophysical understanding of the nature of blood flow through the cardiovascular system.…

Cross-sectional relations of arterial stiffness, pressure pulsatility, wave reflection, and arterial calcification.

PubMed

Tsao, Connie W; Pencina, Karol M; Massaro, Joseph M; Benjamin, Emelia J; Levy, Daniel; Vasan, Ramachandran S; Hoffmann, Udo; O'Donnell, Christopher J; Mitchell, Gary F

2014-11-01

Arterial hemodynamics and vascular calcification are associated with increased risk for cardiovascular disease, but their inter-relations remain unclear. We sought to examine the associations of arterial stiffness, pressure pulsatility, and wave reflection with arterial calcification in individuals free of prevalent cardiovascular disease. Framingham Heart Study Third Generation and Offspring Cohort participants free of cardiovascular disease underwent applanation tonometry to measure arterial stiffness, pressure pulsatility, and wave reflection, including carotid-femoral pulse wave velocity, central pulse pressure, forward wave amplitude, and augmentation index. Participants in each cohort (n=1905, 45±6 years and n=1015, 65±9 years, respectively) underwent multidetector computed tomography to assess the presence and quantity of thoracic aortic calcification, abdominal aortic calcification, and coronary artery calcification. In multivariable-adjusted models, both higher carotid-femoral pulse wave velocity and central pulse pressure were associated with greater thoracic aortic calcification and abdominal aortic calcification, whereas higher augmentation index was associated with abdominal aortic calcification. Among the tonometry measures, carotid-femoral pulse wave velocity was the strongest correlate of all calcification measures in multivariable-adjusted models (odds ratio per SD for thoracic aortic calcification, 2.69 [95% confidence interval, 2.17-3.35]; abdominal aortic calcification, 1.47 [95% confidence interval, 1.26-1.73]; and coronary artery calcification, 1.48 [95% confidence interval, 1.28-1.72]; all P<0.001, respectively). We observed stronger relations of carotid-femoral pulse wave velocity, central pulse pressure, and forward wave amplitude with nearly all continuous calcification measures in the younger Third Generation Cohort as compared with the Offspring Cohort. In community-dwelling individuals without prevalent cardiovascular disease, abnormal central arterial hemodynamics were positively associated with vascular calcification and were observed at younger ages than previously recognized. The mechanisms of these associations may be bidirectional and deserve further study. © 2014 American Heart Association, Inc.

Detection of Low-volume Blood Loss: Compensatory Reserve Versus Traditional Vital Signs

DTIC Science & Technology

2014-01-01

studies have demonstrated that photoplethysmogram (PPG) wave forms obtained with a pulse oximeter sensor significantly change with volume loss.5 With this...donation, including PPG wave forms (OEM III pulse oximeter , Nonin, Minneapolis, MN), and a noninvasive BPwave form (ccNexfin, Edwards Lifesciences, Irvine...a PPG wave form obtained with a pulse oximeter sensor. CRI is calculated after 30 heart beats and is recalculated beat-to-beat in a continuous

Electromagnetic or other directed energy pulse launcher

DOEpatents

Ziolkowski, Richard W.

1990-01-01

The physical realization of new solutions of wave propagation equations, such as Maxwell's equations and the scaler wave equation, produces localized pulses of wave energy such as electromagnetic or acoustic energy which propagate over long distances without divergence. The pulses are produced by driving each element of an array of radiating sources with a particular drive function so that the resultant localized packet of energy closely approximates the exact solutions and behaves the same.

Local spectrum analysis of field propagation in an anisotropic medium. Part II. Time-dependent fields.

PubMed

Tinkelman, Igor; Melamed, Timor

2005-06-01

In Part I of this two-part investigation [J. Opt. Soc. Am. A 22, 1200 (2005)], we presented a theory for phase-space propagation of time-harmonic electromagnetic fields in an anisotropic medium characterized by a generic wave-number profile. In this Part II, these investigations are extended to transient fields, setting a general analytical framework for local analysis and modeling of radiation from time-dependent extended-source distributions. In this formulation the field is expressed as a superposition of pulsed-beam propagators that emanate from all space-time points in the source domain and in all directions. Using time-dependent quadratic-Lorentzian windows, we represent the field by a phase-space spectral distribution in which the propagating elements are pulsed beams, which are formulated by a transient plane-wave spectrum over the extended-source plane. By applying saddle-point asymptotics, we extract the beam phenomenology in the anisotropic environment resulting from short-pulsed processing. Finally, the general results are applied to the special case of uniaxial crystal and compared with a reference solution.

Measurement of Aortic Pulse Wave Velocity With a Connected Bathroom Scale

PubMed Central

Campo, David; Khettab, Hakim; Yu, Roger; Genain, Nicolas; Edouard, Paul; Buard, Nadine

2017-01-01

Abstract BACKGROUND Measurement of arterial stiffness should be more available. Our aim was to show that aortic pulse wave velocity can be reliably measured with a bathroom scale combining the principles of ballistocardiography (BCG) and impedance plethysmography on a single foot. METHOD The calibration of the bathroom scale was conducted on a group of 106 individuals. The aortic pulse wave velocity was measured with the SphygmoCor in the supine position. Three consecutive measurements were then performed on the Withings scale in the standing position. This aorta-leg pulse transit time (alPTT) was then converted into a velocity with the additional input of the height of the person. Agreement between the SphygmoCor and the bathroom scale so calibrated is assessed on a separate group of 86 individuals, following the same protocol. RESULTS The bias is 0.25 m·s−1 and the SE 1.39 m·s−1. This agreement with Sphygmocor is “acceptable” according to the ARTERY classification. The alPTT correlated well with cfPTT with (Spearman) R = 0.73 in pooled population (cal 0.79, val 0.66). The aorta-leg pulse wave velocity correlated with carotid-femoral pulse wave velocity with R = 0.76 (cal 0.80, val 0.70). CONCLUSION Estimation of the aortic pulse wave velocity is feasible with a bathroom scale. Further investigations are needed to improve the repeatability of measurements and to test their accuracy in different populations and conditions. PMID:28520843

Relationship between glycaemic levels and arterial stiffness in non-diabetic adults.

PubMed

Cavero-Redondo, Iván; Martínez-Vizcaíno, Vicente; Álvarez-Bueno, Celia; Recio-Rodríguez, José Ignacio; Gómez-Marcos, Manuel Ángel; García-Ortiz, Luis

2018-01-23

To examine, in a non-diabetic population, whether the association between arterial stiffness and glycaemic levels depends on the test used as a glycaemic indicator, fasting plasma glucose (FPG) or glycated haemoglobin A1c (HbA1c). A cross-sectional analysis of a 220 non-diabetic subsample from the EVIDENT II study in which FPG, HbA1c and arterial stiffness-related parameters (pulse wave velocity, radial and central augmentation index, and central pulse pressure) were determined. Mean differences in arterial stiffness-related parameters by HbA1c and FPG tertiles were tested using analysis of covariance. All means of arterial stiffness-related parameters increased by HbA1c tertiles, although mean differences were only statistically significant in pulse wave velocity (p ≤.001), even after controlling for potential confounders (HbA1c <5.30% = 6.88 m/s; HbA1c 5.30%-5.59% = 7.06 m/s; and HbA1c ≥5.60% = 8.16 m/s, p =.004). Conversely, mean differences in pulse wave velocity by FPG tertiles did not reach statistically significant differences after controlling for potential confounders (FPG 4.44 mmol/l = 7.18 m/s; FPG 4.44 mmol/l-4.87 mmol/l = 7.26 m/s; and FPG ≥4.88 mmol/l = 7.93 m/s, p =.066). Glucose levels in a non-diabetic population were associated with arterial stiffness but better when levels were determined using HbA1c. Copyright © 2017 Elsevier España, S.L.U. All rights reserved.

Dual-pulses and harmonic patterns of a square-wave soliton in passively mode-locked fiber laser

NASA Astrophysics Data System (ADS)

Ma, Wanzhuo; Wang, Tianshu; Su, Qingchao; Zhang, Jing; Jia, Qingsong; Jiang, Huilin

2018-06-01

We demonstrate a square-wave soliton pulse passively mode-locked fiber laser. The mode-locked pulses are achieved by using a nonlinear amplifying loop mirror. Single-pulse operation at a fundamental repetition rate of 3.2 MHz is obtained. The optical spectrum presents the soliton feature of several sidebands. The pulse duration expands with increasing pump power, but the amplitude hardly varies. Pulse breaking occurs and a stable dual-pulse is obtained with a fixed interval of 48 ns. Harmonic mode-locked states can be achieved when the total pump power is higher than 740 mW. The harmonic pulses can also operate in both single-pulse and dual-pulse states.

Statistical analysis of data and modeling of Nanodust measured by STEREO/WAVES at 1AU

NASA Astrophysics Data System (ADS)

Belheouane, S.; Zaslavsky, A.; Meyer-Vernet, N.; Issautier, K.; Czechowski, A.; Mann, I.; Le Chat, G.; Zouganelis, I.; Maksimovic, M.

2012-12-01

We study the flux of dust particles of nanometer size measured at 1AU by the S/WAVES instrument aboard the twin STEREO spacecraft. When they impact the spacecraft at very high speed, these nanodust particles, first detected by Meyer-Vernet et al. (2009), generate plasma clouds and produce voltage pulses measured by the electric antennas. The Time Domain Sampler (TDS) of the radio and plasma instrument produces temporal windows containing several pulses. We perform a statistical study of the distribution of pulse amplitudes and arrival times in the measuring window during the 2007-2012 period. We interpret the results using simulations of the dynamics of nanodust in the solar wind based on the model of Czechowski and Mann (2010). We also investigate the variations of nanodust fluxes while STEREO rotates about the sunward axis (Roll) ; this reveals that some directions are privilegied.

Coexistence of negative and positive polarity electrostatic solitary waves in ultradense relativistic negative-ion-beam permeated plasmas

NASA Astrophysics Data System (ADS)

Elkamash, I. S.; Kourakis, I.

2018-05-01

The criteria for occurrence and the dynamical features of electrostatic solitary waves in a homogeneous, unmagnetized ultradense plasma penetrated by a negative ion beam are investigated, relying on a quantum hydrodynamic model. The ionic components are modeled as inertial fluids, while the relativistic electrons obey Fermi-Dirac statistics. A new set of exact analytical conditions for localized solitary pulses to exist is obtained, in terms of plasma density. The algebraic analysis reveals that these depend sensitively on the negative ion beam characteristics, that is, the beam velocity and density. Particular attention is paid to the simultaneous occurrence of positive and negative potential pulses, identified by their respective distinct ambipolar electric field structure forms. It is shown that the coexistence of positive and negative potential pulses occurs in a certain interval of parameter values, where the ion beam inertia becomes significant.

Resonant optical pulses on a continuous-wave background in two-level active media

NASA Astrophysics Data System (ADS)

Li, Sitai; Biondini, Gino; Kovačič, Gregor; Gabitov, Ildar

2018-01-01

We present exact N-soliton optical pulses riding on a continuous-wave (c.w.) beam that propagate through and interact with a two-level active optical medium. Their representation is derived via an appropriate generalization of the inverse scattering transform for the corresponding Maxwell-Bloch equations. We describe the single-soliton solutions in detail and classify them into several distinct families. In addition to the analogues of traveling-wave soliton pulses that arise in the absence of a c.w. beam, we obtain breather-like structures, periodic pulse-trains and rogue-wave-type (i.e., rational) pulses, whose existence is directly due to the presence of the c.w. beam. These soliton solutions are the analogues for Maxwell-Bloch systems of the four classical solution types of the focusing nonlinear Schrödinger equation with non-zero background, although the physical behavior of the corresponding solutions is quite different.

Bifurcations and chaos in a parametrically damped two-well Duffing oscillator subjected to symmetric periodic pulses.

PubMed

Chacón, R; Martínez García-Hoz, A

1999-06-01

We study a parametrically damped two-well Duffing oscillator, subjected to a periodic string of symmetric pulses. The order-chaos threshold when altering solely the width of the pulses is investigated theoretically through Melnikov analysis. We show analytically and numerically that most of the results appear independent of the particular wave form of the pulses provided that the transmitted impulse is the same. By using this property, the stability boundaries of the stationary solutions are determined to first approximation by means of an elliptic harmonic balance method. Finally, the bifurcation behavior at the stability boundaries is determined numerically.

Experimental study on the pressure and pulse wave propagation in viscoelastic vessel tubes-effects of liquid viscosity and tube stiffness.

PubMed

Ikenaga, Yuki; Nishi, Shohei; Komagata, Yuka; Saito, Masashi; Lagrée, Pierre-Yves; Asada, Takaaki; Matsukawa, Mami

2013-11-01

A pulse wave is the displacement wave which arises because of ejection of blood from the heart and reflection at vascular bed and distal point. The investigation of pressure waves leads to understanding the propagation characteristics of a pulse wave. To investigate the pulse wave behavior, an experimental study was performed using an artificial polymer tube and viscous liquid. A polyurethane tube and glycerin solution were used to simulate a blood vessel and blood, respectively. In the case of the 40 wt% glycerin solution, which corresponds to the viscosity of ordinary blood, the attenuation coefficient of a pressure wave in the tube decreased from 4.3 to 1.6 dB/m because of the tube stiffness (Young's modulus: 60 to 200 kPa). When the viscosity of liquid increased from approximately 4 to 10 mPa·s (the range of human blood viscosity) in the stiff tube, the attenuation coefficient of the pressure wave changed from 1.6 to 3.2 dB/m. The hardening of the blood vessel caused by aging and the increase of blood viscosity caused by illness possibly have opposite effects on the intravascular pressure wave. The effect of the viscosity of a liquid on the amplitude of a pressure wave was then considered using a phantom simulating human blood vessels. As a result, in the typical range of blood viscosity, the amplitude ratio of the waves obtained by the experiments with water and glycerin solution became 1:0.83. In comparison with clinical data, this value is much smaller than that seen from blood vessel hardening. Thus, it can be concluded that the blood viscosity seldom affects the attenuation of a pulse wave.

Optimization design and laser damage threshold analysis of pulse compression multilayer dielectric gratings

NASA Astrophysics Data System (ADS)

Fan, Shuwei; Bai, Liang; Chen, Nana

2016-08-01

As one of the key elements of high-power laser systems, the pulse compression multilayer dielectric grating is required for broader band, higher diffraction efficiency and higher damage threshold. In this paper, the multilayer dielectric film and the multilayer dielectric gratings(MDG) were designed by eigen matrix and optimized with the help of generic algorithm and rigorous coupled wave method. The reflectivity was close to 100% and the bandwith were over 250nm, twice compared to the unoptimized film structure. The simulation software of standing wave field distribution within MDG was developed and the electric field of the MDG was calculated. And the key parameters which affected the electric field distribution were also studied.

COMPARATIVE DISINFECTION EFFICIENCY OF PULSED AND CONTINUOUS-WAVE UV IRRADIATION TECHNOLOGIES

EPA Science Inventory

Pulsed UV (PUV) is novel UV irradiation system that is a non-mercury lamp based alternative to currently used continuous-wave systems for water disinfection. To compare the polychromatic PUV irradiation disinfection efficiency with that from continuous wave monochromatic low-pre...

Terahertz waves radiated from two noncollinear femtosecond plasma filaments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Du, Hai-Wei; Hoshina, Hiromichi; Otani, Chiko, E-mail: otani@riken.jp

2015-11-23

Terahertz (THz) waves radiated from two noncollinear femtosecond plasma filaments with a crossing angle of 25° are investigated. The irradiated THz waves from the crossing filaments show a small THz pulse after the main THz pulse, which was not observed in those from single-filament scheme. Since the position of the small THz pulse changes with the time-delay of two filaments, this phenomenon can be explained by a model in which the small THz pulse is from the second filament. The denser plasma in the overlap region of the filaments changes the movement of space charges in the plasma, thereby changingmore » the angular distribution of THz radiation. As a result, this schematic induces some THz wave from the second filament to propagate along the path of the THz wave from the first filament. Thus, this schematic alters the direction of the THz radiation from the filamentation, which can be used in THz wave remote sensing.« less

Attosecond transient absorption of a bound wave packet coupled to a smooth continuum

DOE PAGES

Dahlström, Jan Marcus; Pabst, Stefan; Lindroth, Eva

2017-10-16

Here, we investigate the possibility of using transient absorption of a coherent bound electron wave packet in hydrogen as an attosecond pulse characterization technique. In a recent work, we have shown that photoionization of such a coherent bound electron wave packet opens up for pulse characterization with unprecedented temporal accuracy—independent of the atomic structure—with maximal photoemission at all kinetic energies given a wave packet with zero relative phase. Here, we perform numerical propagation of the time-dependent Schrödinger equation and analytical calculations based on perturbation theory to show that the energy-resolved maximal absorption of photons from the attosecond pulse does not uniquely occur at a zero relative phase of the initial wave packet. Instead, maximal absorption occurs at different relative wave packet phases, distributed as a non-monotonous function with a smoothmore » $$-\\pi /2$$ shift across the central photon energy (given a Fourier-limited Gaussian pulse). Similar results are also found in helium. Our finding is surprising, because it implies that the energy-resolved photoelectrons are not mapped one-to-one with the energy-resolved absorbed photons of the attosecond pulse.« less

Design of a Continuous Blood Pressure Measurement System Based on Pulse Wave and ECG Signals.

PubMed

Li, Jian-Qiang; Li, Rui; Chen, Zhuang-Zhuang; Deng, Gen-Qiang; Wang, Huihui; Mavromoustakis, Constandinos X; Song, Houbing; Ming, Zhong

2018-01-01

With increasingly fierce competition for jobs, the pressures on people have risen in recent years, leading to lifestyle and diet disorders that result in significantly higher risks of cardiovascular disease. Hypertension is one of the common chronic cardiovascular diseases; however, mainstream blood pressure measurement devices are relatively heavy. When multiple measurements are required, the user experience and the measurement results may be unsatisfactory. In this paper, we describe the design of a signal collection module that collects pulse waves and electrocardiograph (ECG) signals. The collected signals are input into a signal processing module to filter the noise and amplify the useful physiological signals. Then, we use a wavelet transform to eliminate baseline drift noise and detect the feature points of the pulse waves and ECG signals. We propose the concept of detecting the wave shape associated with an instance, an approach that minimizes the impact of atypical pulse waves on blood pressure measurements. Finally, we propose an improved method for measuring blood pressure based on pulse wave velocity that improves the accuracy of blood pressure measurements by 58%. Moreover, the results meet the american medical instrument promotion association standards, which demonstrate the feasibility of our measurement system.

Attosecond transient absorption of a bound wave packet coupled to a smooth continuum

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dahlström, Jan Marcus; Pabst, Stefan; Lindroth, Eva

Here, we investigate the possibility of using transient absorption of a coherent bound electron wave packet in hydrogen as an attosecond pulse characterization technique. In a recent work, we have shown that photoionization of such a coherent bound electron wave packet opens up for pulse characterization with unprecedented temporal accuracy—independent of the atomic structure—with maximal photoemission at all kinetic energies given a wave packet with zero relative phase. Here, we perform numerical propagation of the time-dependent Schrödinger equation and analytical calculations based on perturbation theory to show that the energy-resolved maximal absorption of photons from the attosecond pulse does not uniquely occur at a zero relative phase of the initial wave packet. Instead, maximal absorption occurs at different relative wave packet phases, distributed as a non-monotonous function with a smoothmore » $$-\\pi /2$$ shift across the central photon energy (given a Fourier-limited Gaussian pulse). Similar results are also found in helium. Our finding is surprising, because it implies that the energy-resolved photoelectrons are not mapped one-to-one with the energy-resolved absorbed photons of the attosecond pulse.« less

Design of a Continuous Blood Pressure Measurement System Based on Pulse Wave and ECG Signals

PubMed Central

Li, Jian-Qiang; Li, Rui; Chen, Zhuang-Zhuang; Deng, Gen-Qiang; Wang, Huihui; Mavromoustakis, Constandinos X.; Ming, Zhong

2018-01-01

With increasingly fierce competition for jobs, the pressures on people have risen in recent years, leading to lifestyle and diet disorders that result in significantly higher risks of cardiovascular disease. Hypertension is one of the common chronic cardiovascular diseases; however, mainstream blood pressure measurement devices are relatively heavy. When multiple measurements are required, the user experience and the measurement results may be unsatisfactory. In this paper, we describe the design of a signal collection module that collects pulse waves and electrocardiograph (ECG) signals. The collected signals are input into a signal processing module to filter the noise and amplify the useful physiological signals. Then, we use a wavelet transform to eliminate baseline drift noise and detect the feature points of the pulse waves and ECG signals. We propose the concept of detecting the wave shape associated with an instance, an approach that minimizes the impact of atypical pulse waves on blood pressure measurements. Finally, we propose an improved method for measuring blood pressure based on pulse wave velocity that improves the accuracy of blood pressure measurements by 58%. Moreover, the results meet the american medical instrument promotion association standards, which demonstrate the feasibility of our measurement system. PMID:29541556

Analysis of pulse thermography using similarities between wave and diffusion propagation

NASA Astrophysics Data System (ADS)

Gershenson, M.

2017-05-01

Pulse thermography or thermal wave imaging are commonly used as nondestructive evaluation (NDE) method. While the technical aspect has evolve with time, theoretical interpretation is lagging. Interpretation is still using curved fitting on a log log scale. A new approach based directly on the governing differential equation is introduced. By using relationships between wave propagation and the diffusive propagation of thermal excitation, it is shown that one can transform from solutions in one type of propagation to the other. The method is based on the similarities between the Laplace transforms of the diffusion equation and the wave equation. For diffusive propagation we have the Laplace variable s to the first power, while for the wave propagation similar equations occur with s2. For discrete time the transformation between the domains is performed by multiplying the temperature data vector by a matrix. The transform is local. The performance of the techniques is tested on synthetic data. The application of common back projection techniques used in the processing of wave data is also demonstrated. The combined use of the transform and back projection makes it possible to improve both depth and lateral resolution of transient thermography.

Pulse dynamics of dual-wavelength dissipative soliton resonances and domain wall solitons in a Tm fiber laser with fiber-based Lyot filter.

PubMed

Wang, Pan; Zhao, Kangjun; Xiao, Xiaosheng; Yang, Changxi

2017-11-27

We report on the first demonstration of dual-wavelength square-wave pulses in a thulium-doped fiber laser. Under appropriate cavity parameters, dual-wavelength dissipative soliton resonances (DSRs) and domain wall solitons (DWSs) are successively obtained. Meanwhile, dark pulses generation is achieved at the dual-wavelength DWSs region due to the overlap of the two domain wall pulses. The fiber-based Lyot filter, conducted by inserting PMF between an in-line PBS and a PD-ISO, facilitates the generation of dual-wavelength operation. The polarization-resolved investigation suggests that the cross coupling between two orthogonal polarization components in the high nonlinear fiber plays an important role in the square-wave pulses formation. The investigation may be helpful for further understanding the square-wave pulse formation and has potential in application filed of multi-wavelength pulsed fiber lasers.

Acousto-optic modulation and opto-acoustic gating in piezo-optomechanical circuits

PubMed Central

Balram, Krishna C.; Davanço, Marcelo I.; Ilic, B. Robert; Kyhm, Ji-Hoon; Song, Jin Dong; Srinivasan, Kartik

2017-01-01

Acoustic wave devices provide a promising chip-scale platform for efficiently coupling radio frequency (RF) and optical fields. Here, we use an integrated piezo-optomechanical circuit platform that exploits both the piezoelectric and photoelastic coupling mechanisms to link 2.4 GHz RF waves to 194 THz (1550 nm) optical waves, through coupling to propagating and localized 2.4 GHz acoustic waves. We demonstrate acousto-optic modulation, resonant in both the optical and mechanical domains, in which waveforms encoded on the RF carrier are mapped to the optical field. We also show opto-acoustic gating, in which the application of modulated optical pulses interferometrically gates the transmission of propagating acoustic pulses. The time-domain characteristics of this system under both pulsed RF and pulsed optical excitation are considered in the context of the different physical pathways involved in driving the acoustic waves, and modelled through the coupled mode equations of cavity optomechanics. PMID:28580373

2D.02: ACCURACY OF ISOVOLUMETRIC CONTRACTION TIME OBTAINED BY CAROTID ARTERIAL TONOMETRY IN PATIENTS WITH CHRONIC LEFT VENTRICULAR FAILURE.

PubMed

Salvi, L; Grillo, A; Marelli, S; Gao, L; Giuliano, A; Trifirò, G; Santini, F; Pini, A; Salvi, P; Viecca, F; Carretta, R; Parati, G

2015-06-01

The Buckberg index (SEVR: subendocardial viability ratio) is considered a useful parameter for a non-invasive assessment of the relationship between subendocardial oxygen supply and demand. However, his classic calculation does not include the pre-ejection isovolumic contraction time in stroke work evaluation. The aim of our study was to evaluate the accuracy of the isovolumic contraction time obtained through the carotid pulse wave analysis, to be included in SEVR assessment. In 35 patients (mean age ± SD = 66 ± 13 yrs) followed-up for chronic left ventricular systolic failure (EF = 32 ± 8%) with no significant valvular disease, the pressure curve in the common carotid artery by tonometer (PulsePen) and the aortic transvalvular flow by EchocardioDoppler (Philips-EnVisor C-HD) were acquired simultaneously. The synchronization of data acquisition was verified by comparison of the RR intervals in the ECG signals recorded simultaneously to the two methods. The isovolumic contraction time was separately calculated by considering both the delay between the beginning of the aortic flow wave obtained by EchocardioDoppler and the R wave of the corresponding ECG, and the delay between the foot of the pressure wave recorded in the carotid artery by tonometry compared with the R wave of the corresponding ECG. The latter was corrected by considering the delay between ascending aorta and carotid pulses, computed as a function of the carotid-femoral pulse wave speed and of the distance between the point of carotid pulse acquisition and the sternal notch. The isovolumic contraction time computed by tonometry (68.8 ± 20.2 ms) was closely related to that measured with the EchocardioDoppler approach (68.8 ± 20.5 ms): y = 0.93x + 4.94; r = 0.93; p < 0.0001, with homogeneous distribution in Bland-Altman analysis (mean difference -0.1 ± 7.57 ms). The ratios between isovolumic contraction time and systolic ejection time separately obtained with the two methods (24.8 ± 8.3% and 22.2 ± 8.5%, respectively) were closely related: y = 0.93x + 1.67; r = 0.90 (mean difference -0.1 ± 2.7%). Thus, carotid arterial tonometry allows an accurate and simple assessment of the isovolumic contraction time, which can be employed to improve the assessment of SEVR by also considering the isovolumic contraction time in the stroke work evaluation.

Seismic excitation by the space shuttle Columbia

USGS Publications Warehouse

Kanamori, H.; Mori, J.; Anderson, D.L.; Heaton, T.H.

1991-01-01

SEISMIC stations in southern California recorded the atmospheric shock waves generated by the space shuttle Columbia on its return to the Edwards Air Force base on 13 August 1989 (Fig. 1). In addition to the shock wave, the broad-band IRIS-TERRAscope station at Pasadena recorded a distinct pulse with a period of ???2-3 seconds, which arrived 12.5 seconds before the shock wave (Fig. 2). This pulse was also recorded at the University of Southern California, near downtown Los Angeles, where it arrived 3 seconds after the shock wave. The origin of this pulse could not be readily identified. We show here that it was a seismic P wave excited by the motion of high-rise buildings in downtown Los Angeles, which were hit by the shock wave. The proximity of the natural period of the high-rise buildings to that of the Los Angeles basin enabled efficient energy transfer from shock wave to seismic wave.

Relationships between 24-h blood pressure variability and 24-h central arterial pressure, pulse wave velocity and augmentation index in hypertensive patients.

PubMed

Omboni, Stefano; Posokhov, Igor N; Rogoza, Anatoly N

2017-04-01

Twenty-four-h blood pressure variability (BPV) predicts cardiovascular complications in hypertension, but its association with pulse wave indices (central arterial pressure, pulse wave velocity (PWV) and augmentation index (AIx)) is poorly understood. In the present study, we assessed the degree of the effect of 24-h BPV on 24-h pulse wave indices. Brachial blood pressure was measured non-invasively over the 24 h with an electronic, oscillometric, automated device (BPLab) in 661 uncomplicated treated or untreated hypertensive patients. Digitalized oscillometric waveforms were analyzed with a validated algorithm to obtain pulse wave indices. Twenty-four-h BPV was calculated as the unweighted (SDu) or weighted s.d. (SDw) of the mean blood pressure or as the average real variability (ARV). Twenty-four-h systolic BPV showed a direct and significant relationship with the central arterial systolic pressure (r=0.28 SDu, r=0.40 SDw, r=0.34 ARV), PWV (r=0.10 SDu, r=0.21 SDw, r=0.19 ARV) and AIx (r=0.17 SDu, r=0.27 SDw, r=0.23 ARV). After adjustment for age, sex, body mass index, antihypertensive treatment and 24-h systolic blood pressure, the relationship lost some power but was still significant for all measures, except for the AIx. Pulse wave indices were higher in patients with high BPV than in those with low BPV: after adjustment, these differences were abolished for the AIx. The diastolic BPV showed a weak association with the pulse wave indices. In conclusion, in hypertensive patients, 24-h systolic BPV is moderately and independently associated with 24-h central arterial pressure and stiffness.

Arterial stiffness is associated to cardiorespiratory fitness and body mass index in young Swedish adults: The Lifestyle, Biomarkers, and Atherosclerosis study.

PubMed

Fernberg, Ulrika; Fernström, Maria; Hurtig-Wennlöf, Anita

2017-11-01

Background Early changes in the large muscular arteries are already associated with risk factors as hypertension and obesity in adolescence and young adulthood. The present study examines the association between arterial stiffness measurements, pulse wave velocity and augmentation index and lifestyle-related factors, body composition and cardiorespiratory fitness, in young, healthy, Swedish adults. Design This study used a population-based cross-sectional sample. Methods The 834 participants in the study were self-reported healthy, non-smoking, age 18-25 years. Augmentation index and pulse wave velocity were measured with applanation tonometry. Cardiorespiratory fitness was measured by ergometer bike test to estimate maximal oxygen uptake. Body mass index (kg/m 2 ) was calculated and categorised according to classification by the World Health Organisation. Results Young Swedish adults with obesity and low cardiorespiratory fitness have significantly higher pulse wave velocity and augmentation index than non-obese young adults with medium or high cardiorespiratory fitness. The observed U-shaped association between pulse wave velocity and body mass index categories in women indicates that it might be more beneficial to be normal weight than underweight when assessing the arterial stiffness with pulse wave velocity. The highest mean pulse wave velocity was found in overweight/obese individuals with low cardiorespiratory fitness. The lowest mean pulse wave velocity was found in normal weight individuals with high cardiorespiratory fitness. Cardiorespiratory fitness had a stronger effect than body mass index on arterial stiffness in multiple regression analyses. Conclusions The inverse association between cardiorespiratory fitness and arterial stiffness is observed already in young adults. The study result highlights the importance of high cardiorespiratory fitness, but also that underweight individuals may be a possible risk group that needs to be further studied.

Molecular dynamics study of lubricant depletion by pulsed laser heating

NASA Astrophysics Data System (ADS)

Seo, Young Woo; Rosenkranz, Andreas; Talke, Frank E.

2018-05-01

In this study, molecular dynamics simulations were performed to numerically investigate the effect of pulsed laser heating on lubricant depletion. The maximum temperature, the lubricant depletion width, the number of evaporated lubricant beads and the number of fragmented lubricant chains were studied as a function of laser peak power, pulse duration and repetition rate. A continuous-wave laser and a square pulse laser were simulated and compared to a Gaussian pulse laser. With increasing repetition rate, pulsed laser heating was found to approach continuous-wave laser heating.

Comparison of an Oscillometric Method with Cardiac Magnetic Resonance for the Analysis of Aortic Pulse Wave Velocity

PubMed Central

Feistritzer, Hans-Josef; Reinstadler, Sebastian J.; Klug, Gert; Kremser, Christian; Seidner, Benjamin; Esterhammer, Regina; Schocke, Michael F.; Franz, Wolfgang-Michael; Metzler, Bernhard

2015-01-01

Objectives Pulse wave velocity (PWV) is the proposed gold-standard for the assessment of aortic elastic properties. The aim of this study was to compare aortic PWV determined by a recently developed oscillometric device with cardiac magnetic resonance imaging (CMR). Methods PWV was assessed in 40 volunteers with two different methods. The oscillometric method (PWVOSC) is based on a transfer function from the brachial pressure waves determined by oscillometric blood pressure measurements with a common cuff (Mobil-O-Graph, I.E.M. Stolberg, Germany). CMR was used to determine aortic PWVCMR with the use of the transit time method based on phase-contrast imaging at the level of the ascending and abdominal aorta on a clinical 1.5 Tesla scanner (Siemens, Erlangen, Germany). Results The median age of the study population was 34 years (IQR: 24–55 years, 11 females). A very strong correlation was found between PWVOSC and PWVCMR (r = 0.859, p < 0.001). Mean PWVOSC was 6.7 ± 1.8 m/s and mean PWVCMR was 6.1 ± 1.8 m/s (p < 0.001). Analysis of agreement between the two measurements using Bland-Altman method showed a bias of 0.57 m/s (upper and lower limit of agreement: 2.49 m/s and -1.34 m/s). The corresponding coefficient of variation between both measurements was 15%. Conclusion Aortic pulse wave velocity assessed by transformation of the brachial pressure waveform showed an acceptable agreement with the CMR-derived transit time method. PMID:25612307

A database of virtual healthy subjects to assess the accuracy of foot-to-foot pulse wave velocities for estimation of aortic stiffness.

PubMed

Willemet, Marie; Chowienczyk, Phil; Alastruey, Jordi

2015-08-15

While central (carotid-femoral) foot-to-foot pulse wave velocity (PWV) is considered to be the gold standard for the estimation of aortic arterial stiffness, peripheral foot-to-foot PWV (brachial-ankle, femoral-ankle, and carotid-radial) are being studied as substitutes of this central measurement. We present a novel methodology to assess theoretically these computed indexes and the hemodynamics mechanisms relating them. We created a database of 3,325 virtual healthy adult subjects using a validated one-dimensional model of the arterial hemodynamics, with cardiac and arterial parameters varied within physiological healthy ranges. For each virtual subject, foot-to-foot PWV was computed from numerical pressure waveforms at the same locations where clinical measurements are commonly taken. Our numerical results confirm clinical observations: 1) carotid-femoral PWV is a good indicator of aortic stiffness and correlates well with aortic PWV; 2) brachial-ankle PWV overestimates aortic PWV and is related to the stiffness and geometry of both elastic and muscular arteries; and 3) muscular PWV (carotid-radial, femoral-ankle) does not capture the stiffening of the aorta and should therefore not be used as a surrogate for aortic stiffness. In addition, our analysis highlights that the foot-to-foot PWV algorithm is sensitive to the presence of reflected waves in late diastole, which introduce errors in the PWV estimates. In this study, we have created a database of virtual healthy subjects, which can be used to assess theoretically the efficiency of physiological indexes based on pulse wave analysis. Copyright © 2015 the American Physiological Society.

A database of virtual healthy subjects to assess the accuracy of foot-to-foot pulse wave velocities for estimation of aortic stiffness

PubMed Central

Chowienczyk, Phil; Alastruey, Jordi

2015-01-01

While central (carotid-femoral) foot-to-foot pulse wave velocity (PWV) is considered to be the gold standard for the estimation of aortic arterial stiffness, peripheral foot-to-foot PWV (brachial-ankle, femoral-ankle, and carotid-radial) are being studied as substitutes of this central measurement. We present a novel methodology to assess theoretically these computed indexes and the hemodynamics mechanisms relating them. We created a database of 3,325 virtual healthy adult subjects using a validated one-dimensional model of the arterial hemodynamics, with cardiac and arterial parameters varied within physiological healthy ranges. For each virtual subject, foot-to-foot PWV was computed from numerical pressure waveforms at the same locations where clinical measurements are commonly taken. Our numerical results confirm clinical observations: 1) carotid-femoral PWV is a good indicator of aortic stiffness and correlates well with aortic PWV; 2) brachial-ankle PWV overestimates aortic PWV and is related to the stiffness and geometry of both elastic and muscular arteries; and 3) muscular PWV (carotid-radial, femoral-ankle) does not capture the stiffening of the aorta and should therefore not be used as a surrogate for aortic stiffness. In addition, our analysis highlights that the foot-to-foot PWV algorithm is sensitive to the presence of reflected waves in late diastole, which introduce errors in the PWV estimates. In this study, we have created a database of virtual healthy subjects, which can be used to assess theoretically the efficiency of physiological indexes based on pulse wave analysis. PMID:26055792

Three-wave interaction solitons in optical parametric amplification.

PubMed

Ibragimov, E; Struthers, A A; Kaup, D J; Khaydarov, J D; Singer, K D

1999-05-01

This paper applies three-wave interaction (TWI)-soliton theory to optical parametric amplification when the signal, idler, and pump wave can all contain TWI solitons. We use an analogy between two different velocity regimes to compare the theory with output from an experimental synchronously pumped optical parametric amplifier. The theory explains the observed inability to compress the intermediate group-velocity wave and 20-fold pulse compression in this experiment. The theory and supporting numerics show that one can effectively control the shape and energy of the optical pulses by shifting the TWI solitons in the pulses.

Patterns of Alloy Deformation by Pulsed Pressure

NASA Astrophysics Data System (ADS)

Chebotnyagin, L. M.; Potapov, V. V.; Lopatin, V. V.

2015-06-01

Patterns of alloy deformation for optimization of a welding regime are studied by the method of modeling and deformation profiles providing high deformation quality are determined. A model of stepwise kinetics of the alloy deformation by pulsed pressure from the expanding plasma channel inside of a deformable cylinder is suggested. The model is based on the analogy between the acoustic and electromagnetic wave processes in long lines. The shock wave pattern of alloy deformation in the presence of multiple reflections of pulsed pressure waves in the gap plasma channel - cylinder wall and the influence of unloading waves from free surfaces are confirmed.

Arterial wave reflection and subclinical atherosclerosis in rheumatoid arthritis.

PubMed

Gunter, Sule; Robinson, Chanel; Woodiwiss, Angela J; Norton, Gavin R; Hsu, Hon-Chun; Solomon, Ahmed; Tsang, Linda; Millen, Aletta M E; Dessein, Patrick H

2018-01-01

Atherosclerotic cardiovascular disease risk is increased in rheumatoid arthritis (RA). Wave reflection occurs at arterial branching points, which are particularly prone to atherosclerosis. We explored the relationship of wave reflection with atherosclerosis in RA. One hundred and sixty three RA patients (110 white, 31 Asian, 17 black and 5 of mixed ancestry) without cardiovascular disease participated. Arterial stiffness, wave reflection, pressure pulsatility, plaque in the extracranial carotid artery tree and the mean of the left and right common carotid arteries intima-thickness were determined. Associations were identified in multivariable regression models. One SD increase in reflected wave pressure (OR (95% CI) = 2.54 (1.41-4.44), p=0.001), reflection magnitude (OR (95% CI) = 1.84 (1.17-2.89), p=0.008), central pulse pressure (OR (95% CI) = 1.89 (1.12-3.22), p=0.02) and peripheral pulse pressure (OR (95% CI) = 2.09 (1.23-3.57), p=0.007) were associated with plaque. The association of wave reflection with plaque was independent of arterial stiffness and pressure pulsatility, and was present in both hypertensive and normotensive RA patients. In receiver operator characteristic curve analysis, the optimal cutoff value for reflected wave pressure in predicting plaque presence was 25 mmHg with a sensitivity, specificity, positive predictive value and negative predictive value of 45.2%, 89.3%, 78.6% and 66.2%, respectively; a reflected wave pressure of >25 mmHg was associated with plaque in univariate and adjusted analysis (p<0.0001 for both). Arterial function was not independently related to carotid intima-media thickness. Consideration and therapeutic targeting of wave reflection may improve cardiovascular disease prevention in RA.

EFFECTS OF CONTINUOUS-WAVE, PULSED, AND SINUSOIDAL-AMPLITUDE-MODULATED MICROWAVES ON BRAIN ENERGY METABOLISM

EPA Science Inventory

A comparison of the effects of continuous wave, sinusoidal-amplitude modulated, and pulsed square-wave-modulated 591-MHz microwave exposures on brain energy metabolism was made in male Sprague Dawley rats (175-225g). Brain NADH fluorescence, adensine triphosphate (ATP) concentrat...

Electromagnetic pulse propagation in dispersive planar dielectrics.

PubMed

Moten, K; Durney, C H; Stockham, T G

1989-01-01

The responses of a plane-wave pulse train irradiating a lossy dispersive dielectric half-space are investigated. The incident pulse train is expressed as a Fourier series with summing done by the inverse fast Fourier transform. The Fourier series technique is adopted to avoid the many difficulties often encountered in finding the inverse Fourier transform when transform analyses are used. Calculations are made for propagation in pure water, and typical waveforms inside the dielectric half-space are presented. Higher harmonics are strongly attenuated, resulting in a single continuous sinusoidal waveform at the frequency of the fundamental depth in the material. The time-averaged specific absorption rate (SAR) for pulse-train propagation is shown to be the sum of the time-averaged SARs of the individual harmonic components of the pulse train. For the same average power, calculated SARs reveal that pulse trains generally penetrate deeper than carrier-frequency continuous waves but not deeper than continuous waves at frequencies approaching the fundamental of the pulse train. The effects of rise time on the propagating pulse train in the dielectrics are shown and explained. Since most practical pulsed systems are very limited in bandwidth, no pronounced differences between their response and continuous wave (CW) response would be expected. Typical results for pulse-train propagation in arrays of dispersive planar dielectric slabs are presented. Expressing the pulse train as a Fourier series provides a practical way of interpreting the dispersion characteristics from the spectral point of view.

Design, development and testing twin pulse tube cryocooler

NASA Astrophysics Data System (ADS)

Gour, Abhay Singh; Sagar, Pankaj; Karunanithi, R.

2017-09-01

The design and development of Twin Pulse Tube Cryocooler (TPTC) is presented. Both the coolers are driven by a single Linear Moving Magnet Synchronous Motor (LMMSM) with piston heads at both ends of the mover shaft. Magnetostatic analysis for flux line distribution was carried-out during design and development of LMMSM based pressure wave generator. Based on the performance of PWG, design of TPTC was carried out using Sage and Computational Fluid Dynamics (CFD) analysis. Detailed design, fabrication and testing of LMMSM, TPTC and their integration tests are presented in this paper.

Assessing mental stress from the photoplethysmogram: a numerical study

PubMed Central

Charlton, Peter H; Celka, Patrick; Farukh, Bushra; Chowienczyk, Phil; Alastruey, Jordi

2018-01-01

Abstract Objective: Mental stress is detrimental to cardiovascular health, being a risk factor for coronary heart disease and a trigger for cardiac events. However, it is not currently routinely assessed. The aim of this study was to identify features of the photoplethysmogram (PPG) pulse wave which are indicative of mental stress. Approach: A numerical model of pulse wave propagation was used to simulate blood pressure signals, from which simulated PPG pulse waves were estimated using a transfer function. Pulse waves were simulated at six levels of stress by changing the model input parameters both simultaneously and individually, in accordance with haemodynamic changes associated with stress. Thirty-two feature measurements were extracted from pulse waves at three measurement sites: the brachial, radial and temporal arteries. Features which changed significantly with stress were identified using the Mann–Kendall monotonic trend test. Main results: Seventeen features exhibited significant trends with stress in measurements from at least one site. Three features showed significant trends at all three sites: the time from pulse onset to peak, the time from the dicrotic notch to pulse end, and the pulse rate. More features showed significant trends at the radial artery (15) than the brachial (8) or temporal (7) arteries. Most features were influenced by multiple input parameters. Significance: The features identified in this study could be used to monitor stress in healthcare and consumer devices. Measurements at the radial artery may provide superior performance than the brachial or temporal arteries. In vivo studies are required to confirm these observations. PMID:29658894

Giant pulses of the Crab Nebula pulsar as an indicator of a strong electromagnetic wave

NASA Astrophysics Data System (ADS)

Popov, M. V.; Rudnitskii, A. G.; Soglasnov, V. A.

2017-03-01

The spectra and visibility functions of giant pulses of the Crab Nebula pulsar derived from VLBI observations carried out through the "RadioAstron" project in 2015 are analyzed. Parameters of the scattering of the pulses in the interstellar medium are measured, namely, the scattering time and decorrelation bandwidth. A comparative analysis of the shapes of the spectra and visibility functions of giant pulses obtained in real observations and via modeling of their scattering is carried out. The results suggest the presence of short bursts ( dt < 30 ns) in the structure of the giant pulses at 1668 MHz, whose brightness temperatures exceed 1038 K. These pulses propagate in the pulsar magnetosphere in a strong electromagneticwave regime, leading to the generation of additional radiation perpendicular to the direction of propagation of the giant pulses. This radiation may be associated with anomalous components of the mean pulse profile observed at frequencies above 4 GHz.

Numerical modeling of optical levitation and trapping of the "stuck" particles with a pulsed optical tweezers.

PubMed

Deng, Jian-Liao; Wei, Qing; Wang, Yu-Zhu; Li, Yong-Qing

2005-05-16

We present the theoretical analysis and the numerical modeling of optical levitation and trapping of the stuck particles with a pulsed optical tweezers. In our model, a pulsed laser was used to generate a large gradient force within a short duration that overcame the adhesive interaction between the stuck particles and the surface; and then a low power continuous-wave(cw) laser was used to capture the levitated particle. We describe the gradient force generated by the pulsed optical tweezers and model the binding interaction between the stuck beads and glass surface by the dominative van der Waals force with a randomly distributed binding strength. We numerically calculate the single pulse levitation efficiency for polystyrene beads as the function of the pulse energy, the axial displacement from the surface to the pulsed laser focus and the pulse duration. The result of our numerical modeling is qualitatively consistent with the experimental result.

Improving the output voltage waveform of an intense electron-beam accelerator based on helical type Blumlein pulse forming line

NASA Astrophysics Data System (ADS)

Cheng, Xin-Bing; Liu, Jin-Liang; Zhang, Hong-Bo; Feng, Jia-Huai; Qian, Bao-Liang

2010-07-01

The Blumlein pulse forming line (BPFL) consisting of an inner coaxial pulse forming line (PFL) and an outer coaxial PFL is widely used in the field of pulsed power, especially for intense electron-beam accelerators (IEBA). The output voltage waveform determines the quality and characteristics of the output beam current of the IEBA. Comparing with the conventional BPFL, an IEBA based on a helical type BPFL can increase the duration of the output voltage in the same geometrical volume. However, for the helical type BPFL, the voltage waveform on a matched load may be distorted which influences the electron-beam quality. In this paper, an IEBA based on helical type BPFL is studied theoretically. Based on telegrapher equations of the BPFL, a formula for the output voltage of IEBA is obtained when the transition section is taken into account, where the transition section is between the middle cylinder of BPFL and the load. From the theoretical analysis, it is found that the wave impedance and transit time of the transition section influence considerably the main pulse voltage waveform at the load, a step is formed in front of the main pulse, and a sharp spike is also formed at the end of the main pulse. In order to get a well-shaped square waveform at the load and to improve the electron-beam quality of such an accelerator, the wave impedance of the transition section should be equal to that of the inner PFL of helical type BPFL and the transit time of the transition section should be designed as short as possible. Experiments performed on an IEBA with the helical type BPFL show reasonable agreement with theoretical analysis.

High-gain thompson-scattering X-ray free-electron laser by time-synchronic laterally tilted optical wave

DOEpatents

Chang, Chao; Tang, Chuanxiang; Wu, Juhao

2017-05-09

An improved optical undulator for use in connection with free electron radiation sources is provided. A tilt is introduced between phase fronts of an optical pulse and the pulse front. Two such pulses in a counter-propagating geometry overlap to create a standing wave pattern. A line focus is used to increase the intensity of this standing wave pattern. An electron beam is aligned with the line focus. The relative angle between pulse front and phase fronts is adjusted such that there is a velocity match between the electron beam and the overlapping optical pulses along the line focus. This allows one to provide a long interaction length using short and intense optical pulses, thereby greatly increasing the radiation output from the electron beam as it passes through this optical undulator.

Apparatus for in-situ nondestructive measurement of Young's modulus of plate structures

NASA Technical Reports Server (NTRS)

Huang, Jerry Qixin (Inventor); Perez, Robert J. (Inventor); DeLangis, Leo M. (Inventor)

2005-01-01

A method and apparatus for determining stiffness of a plate-like structure including a monolithic or composite laminate plate entails disposing a device for generating an acoustical pulse against a surface of the plate and disposing a detecting device against the same surface spaced a known distance from the pulse-generating device, and using the pulse-generating device to emit a pulse so as to create an extensional wave in the plate. The detecting device is used to determine a time of flight of the wave over the known distance, and the wave velocity is calculated. A Young's modulus of the plate is determined by a processor based on the wave velocity. Methods and apparatus for evaluating both isotropic plates and anisotropic laminates are disclosed.

Engine Cycle Analysis of Air Breathing Microwave Rocket with Reed Valves

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fukunari, Masafumi; Komatsu, Reiji; Yamaguchi, Toshikazu

The Microwave Rocket is a candidate for a low cost launcher system. Pulsed plasma generated by a high power millimeter wave beam drives a blast wave, and a vehicle acquires impulsive thrust by exhausting the blast wave. The thrust generation process of the Microwave Rocket is similar to a pulse detonation engine. In order to enhance the performance of its air refreshment, the air-breathing mechanism using reed valves is under development. Ambient air is taken to the thruster through reed valves. Reed valves are closed while the inside pressure is high enough. After the time when the shock wave exhaustsmore » at the open end, an expansion wave is driven and propagates to the thrust-wall. The reed valve is opened by the negative gauge pressure induced by the expansion wave and its reflection wave. In these processes, the pressure oscillation is important parameter. In this paper, the pressure oscillation in the thruster was calculated by CFD combined with the flux through from reed valves, which is estimated analytically. As a result, the air-breathing performance is evaluated using Partial Filling Rate (PFR), the ratio of thruster length to diameter L/D, and ratio of opening area of reed valves to superficial area {alpha}. An engine cycle and predicted thrust was explained.« less

In vivo repeatability of the pulse wave inverse problem in human carotid arteries.

PubMed

McGarry, Matthew; Nauleau, Pierre; Apostolakis, Iason; Konofagou, Elisa

2017-11-07

Accurate arterial stiffness measurement would improve diagnosis and monitoring for many diseases. Atherosclerotic plaques and aneurysms are expected to involve focal changes in vessel wall properties; therefore, a method to image the stiffness variation would be a valuable clinical tool. The pulse wave inverse problem (PWIP) fits unknown parameters from a computational model of arterial pulse wave propagation to ultrasound-based measurements of vessel wall displacements by minimizing the difference between the model and measured displacements. The PWIP has been validated in phantoms, and this study presents the first in vivo demonstration. The common carotid arteries of five healthy volunteers were imaged five times in a single session with repositioning of the probe and subject between each scan. The 1D finite difference computational model used in the PWIP spanned from the start of the transducer to the carotid bifurcation, where a resistance outlet boundary condition was applied to approximately model the downstream reflection of the pulse wave. Unknown parameters that were estimated by the PWIP included a 10-segment linear piecewise compliance distribution and 16 discrete cosine transformation coefficients for each of the inlet boundary conditions. Input data was selected to include pulse waves resulting from the primary pulse and dicrotic notch. The recovered compliance maps indicate that the compliance increases close to the bifurcation, and the variability of the average pulse wave velocity estimated through the PWIP is on the order of 11%, which is similar to that of the conventional processing technique which tracks the wavefront arrival time (13%). Copyright © 2017 Elsevier Ltd. All rights reserved.

Measurement of Aortic Pulse Wave Velocity With a Connected Bathroom Scale.

PubMed

Campo, David; Khettab, Hakim; Yu, Roger; Genain, Nicolas; Edouard, Paul; Buard, Nadine; Boutouyrie, Pierre

2017-09-01

Measurement of arterial stiffness should be more available. Our aim was to show that aortic pulse wave velocity can be reliably measured with a bathroom scale combining the principles of ballistocardiography (BCG) and impedance plethysmography on a single foot. The calibration of the bathroom scale was conducted on a group of 106 individuals. The aortic pulse wave velocity was measured with the SphygmoCor in the supine position. Three consecutive measurements were then performed on the Withings scale in the standing position. This aorta-leg pulse transit time (alPTT) was then converted into a velocity with the additional input of the height of the person. Agreement between the SphygmoCor and the bathroom scale so calibrated is assessed on a separate group of 86 individuals, following the same protocol. The bias is 0.25 m·s-1 and the SE 1.39 m·s-1. This agreement with Sphygmocor is "acceptable" according to the ARTERY classification. The alPTT correlated well with cfPTT with (Spearman) R = 0.73 in pooled population (cal 0.79, val 0.66). The aorta-leg pulse wave velocity correlated with carotid-femoral pulse wave velocity with R = 0.76 (cal 0.80, val 0.70). Estimation of the aortic pulse wave velocity is feasible with a bathroom scale. Further investigations are needed to improve the repeatability of measurements and to test their accuracy in different populations and conditions. © The Author 2017. Published by Oxford University Press on behalf of American Journal of Hypertension.

A simplified measurement of pulse wave velocity is not inferior to standard measurement in young adults and children.

PubMed

Edgell, Heather; Stickland, Michael K; MacLean, Joanna E

2016-06-01

The standard measurement of pulse wave velocity (PWV) is restricted by the need for simultaneous tonometry measurements requiring two technicians and expensive equipment, limiting this technique to well-resourced settings. In this preliminary study, we compared a simplified method of pulse wave detection from the finger and toe to pulse wave detection from the carotid and radial arteries using applanation tonometry in children and young adults. We hypothesized that the simplified method of PWV measurement would strongly correlate with the standard measurement in different age groups and oxygen conditions. Participants included (a) boys and girls aged 8-12 years and (b) men and women aged 18-40 years. Participants rested supine while carotid and radial artery pulse waves were measured using applanation tonometry and finger and toe pulse waves were simultaneously collected using a Finometer Midi and a piezo-electric pulse transducer, respectively. These measurements were repeated under hypoxic conditions. Finger-toe PWV measurements were strongly correlated to carotid-radial PWV in adults (R=0.58; P=0.011), but not in children (R=0.056; P=0.610). Finger-toe PWV was sensitive enough to show increases in PWV with age (P<0.0001) and hypoxia in children (P<0.0001) and adults (P=0.003). These results indicate that the simplified measurement of finger-toe PWV strongly correlates with the standard measurement of carotid-radial PWV in adults, but not in children. However, finger-toe PWV can be used in either population to determine changes with hypoxia.

Repetitively Pulsed Backward-Wave Oscillator Investigations

DTIC Science & Technology

1994-03-31

Sinus-6 High Power BWO Experiments and Theory .................. 6 A . B W O physics .............................................................. 6...B. Experiments with high power output of BWO .............................. 8 Section III. Long Pulse Vacuum BWO Experiments...UNM) has completed its initial phase of research on repetitively pulsed high power backward-wave oscillators (BWOs). The aggressive program that we had

Complementary optical rogue waves in parametric three-wave mixing.

PubMed

Chen, Shihua; Cai, Xian-Ming; Grelu, Philippe; Soto-Crespo, J M; Wabnitz, Stefan; Baronio, Fabio

2016-03-21

We investigate the resonant interaction of two optical pulses of the same group velocity with a pump pulse of different velocity in a weakly dispersive quadratic medium and report on the complementary rogue wave dynamics which are unique to such a parametric three-wave mixing. Analytic rogue wave solutions up to the second order are explicitly presented and their robustness is confirmed by numerical simulations, in spite of the onset of modulation instability activated by quantum noise.

Characteristics of the evolution of a plasma generated by radiation from CW and repetitively pulsed CO2 lasers in different gases

NASA Astrophysics Data System (ADS)

Kanevskii, M. F.; Stepanova, M. A.

1990-06-01

The interaction between high-power CW and repetitively pulsed CO2 laser radiation and a low-threshold optical-breakdown plasma near a metal surface is investigated. The characteristics of the breakdown plasma are examined as functions of the experimental conditions. A qualitative analysis of the results obtained was performed using a simple one-dimensional model for laser combustion waves.

Wrinkle-like slip pulse on a fault between different materials

USGS Publications Warehouse

Andrews, D.J.; Ben-Zion, Y.

1997-01-01

Pulses of slip velocity can propagate on a planar interface governed by a constant coefficient of friction, where the interface separates different elastic materials. Such pulses have been found in two-dimensional plane strain finite difference calculations of slip on a fault between elastic media with wave speeds differing by 20%. The self-sustaining propagation of the slip pulse arises from interaction between normal and tangential deformation that exists only with a material contrast. These calculations confirm the prediction of Weertman [1980] that a dislocation propagating steadily along a material interface has a tensile change of normal traction with the same pulse shape as slip velocity. The self-sustaining pulse is associated with a rapid transition from a head wave traveling along the interface with the S wave speed of the faster material, to an opposite polarity body wave traveling with the slower S speed. Slip occurs during the reversal of normal particle velocity. The pulse can propagate in a region with constant coefficient of friction and an initial stress state below the frictional criterion. Propagation occurs in only one direction, the direction of slip in the more compliant medium, with rupture velocity near the slower S wave speed. Displacement is larger in the softer medium, which is displaced away from the fault during the passage of the slip pulse. Motion is analogous to a propagating wrinkle in a carpet. The amplitude of slip remains approximately constant during propagation, but the pulse width decreases and the amplitudes of slip velocity and stress change increase. The tensile change of normal traction increases until absolute normal traction reaches zero. The pulse can be generated as a secondary effect of a drop of shear stress in an asperity. The pulse shape is unstable, and the initial slip pulse can change during propagation into a collection of sharper pulses. Such a pulse enables slip to occur with little loss of energy to friction, while at the same time increasing irregularity of stress and slip at the source. Copyright 1997 by the American Geophysical Union.

Effect of pulse duration on photomechanical response of soft tissue during Ho:YAG laser ablation

NASA Astrophysics Data System (ADS)

Jansen, E. Duco; Motamedi, Massoud; Pfefer, T. Joshua; Asshauer, Thomas; Frenz, Martin; Delacretaz, Guy P.; Abela, George S.; Welch, Ashley J.

1995-05-01

Mechanical injury during pulsed holmium laser ablation of tissue is caused by rapid bubble expansion and collapse or by laser-induced pressure waves. In this study the effect of pulse duration on the photomechanical response of soft tissue during holmium:YAG laser ablation has been investigated. The dynamics of laser-induced bubble formation was documented in water and in transparent polyacrylamide tissue phantoms with a water concentration of 84%. Holmium:YAG laser radiation ((lambda) equals 2.12 micrometers ) was delivered in water or tissue phantoms via an optical fiber (200 or 400 micrometers ). The laser was operated in either the Q- switched mode ((tau) p equals 500 ns, Qp equals 14 +/- 1 mJ, 200 micrometers fiber, Ho equals 446 mJ/mm2) or the free-running mode ((tau) p equals 100 - 1100 microsecond(s) , Qp equals 200 +/- 5 mJ, 400 micrometers fiber, Ho equals 1592 mJ/mm2). Bubble formation was documented using a fast flash photography setup while simultaneously a PVDP needle hydrophone (40 ns risetime), recorded pressures. The effect of the pulse duration on the photomechanical response of soft biological tissue was evaluated by delivering 5 pulses of 800 mJ to the intimal side of porcine aorta in vitro, followed by histologic evaluation. It was observed that, as the pulse duration was increased the bubble shape changed from almost spherical for Q-switched pulses to a more elongated, cylindrical shape for the longer pulse durations. The bubble expansion velocity was larger for shorter pulse durations. A thermo- elastic expansion wave was measured only during Q-switched pulse delivery. All pulses that induced bubble formation generated pressure waves upon collapse of the bubble in water as well as in the gel. The amplitude of the pressure wave depended strongly on the size and geometry of the laser-induced bubble. The important findings of this study were (1) the magnitude of collapse pressure wave decreased as laser pulse duration increased, and (2) mechanical tissue damage is reduced significantly by using longer pulse durations (> 460 microsecond(s) , for the pulse energy used).

Comparison between broadband Bessel beam launchers based on either Bessel or Hankel aperture distribution for millimeter wave short pulse generation.

PubMed

Pavone, Santi C; Mazzinghi, Agnese; Freni, Angelo; Albani, Matteo

2017-08-07

In this paper, a comparison is presented between Bessel beam launchers at millimeter waves based on either a cylindrical standing wave (CSW) or a cylindrical inward traveling wave (CITW) aperture distribution. It is theoretically shown that CITW launchers are better suited for the generation of electromagnetic short pulses because they maintain their performances over a larger bandwidth than those realizing a CSW aperture distribution. Moreover, the wavenumber dispersion of both the launchers is evaluated both theoretically and numerically. To this end, two planar Bessel beam launchers, one enforcing a CSW and the other enforcing a CITW aperture distribution, are designed at millimeter waves with a center operating frequency of f¯=60GHz and analyzed in the bandwidth 50 - 70 GHz by using an in-house developed numerical code to solve Maxwell's equations based on the method of moments. It is shown that a monochromatic Bessel beam can be efficiently generated by both the launchers over a wide fractional bandwidth. Finally, we investigate the generation of limited-diffractive electromagnetic pulses at millimeter waves, up to a certain non-diffractive range. Namely, it is shown that by feeding the launcher with a Gaussian short pulse, a spatially confined electromagnetic pulse can be efficiently generated in front of the launcher.

Imaging and control of interfering wave packets in a dissociating molecule.

PubMed

Skovsen, Esben; Machholm, Mette; Ejdrup, Tine; Thøgersen, Jan; Stapelfeldt, Henrik

2002-09-23

Using two identical 110 femtosecond (fs) optical pulses separated by 310 fs, we launch two dissociative wave packets in I2. We measure the square of the wave function as a function of both the internuclear separation, /Psi(R)/(2), and of the internuclear velocity, /Psi(v(R))/(2), by ionizing the dissociating molecule with an intense 20 fs probe pulse. Strong interference is observed in both /Psi(R)/(2) and in /Psi(v(R))/(2). The interference, and therefore the shape of the wave function, is controlled through the phase difference between the two dissociation pulses in good agreement with calculations.

Diagnostic Analysis Of Ultrasound Data

DOEpatents

Chambers, David H.; Mast, Jeffrey; Azevedo, Stephen G.; Wuebbeling, Frank; Natterer, Frank; Duric, Neb; Littrup, Peter J.; Holsapple, Earle

2006-01-10

A method and apparatus are provided for investigating tissue in which acoustic data are derived from scattering a plurality of pulsed spherical or cylindrical acoustic waves from a plurality of transmission elements through the tissue to a plurality of receiving elements. The acoustic data, which include a mix of reflected and transmitted acoustic waves, are received and digitized, and a representation of a portion of the tissue is generated from the digitized acoustic data.

Reliability of oscillometric central hemodynamic responses to an orthostatic challenge.

PubMed

Stoner, Lee; Bonner, Chantel; Credeur, Daniel; Lambrick, Danielle; Faulkner, James; Wadsworth, Daniel; Williams, Michelle A

2015-08-01

Monitoring central hemodynamic responses to an orthostatic challenge may provide important insight into autonomic nervous system function. Oscillometric pulse wave analysis devices have recently emerged, presenting clinically viable options for investigating central hemodynamic properties. The purpose of the current study was to determine whether oscillometric pulse wave analysis can be used to reliably (between-day) assess central blood pressure and central pressure augmentation (augmentation index) responses to a 5 min orthostatic challenge (modified tilt-table). Twenty healthy adults (26.4 y (SD 5.2), 55% F, 24.7 kg/m(2) (SD 3.8)) were tested on 3 different mornings in the fasted state, separated by a maximum of 7 days. Central hemodynamic variables were assessed on the left arm using an oscillometric device. Repeated measures analysis of variance indicated a significant main effect of the modified tilt-table for all central hemodynamic variables (P < 0.001). In response to the tilt, central diastolic pressure increased by 4.5 mmHg (CI: 2.6, 6.4), central systolic blood pressure increased by 2.3 (CI: 4.4, 0.16) mmHg, and augmentation index decreased by an absolute - 5.3%, (CI: -2.7, -7.9%). The intra-class correlation coefficient values for central diastolic pressure (0.83-0.86), central systolic blood pressure (0.80-0.87) and AIx (0.79-0.82) were above the 0.75 criterion in both the supine and tilted positions, indicating excellent between-day reliability. Central hemodynamic responses to an orthostatic challenge can be assessed with acceptable between-day reliability using oscillometric pulse wave analysis. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Coherence rephasing combined with spin-wave storage using chirped control pulses

NASA Astrophysics Data System (ADS)

Demeter, Gabor

2014-06-01

Photon-echo based optical quantum memory schemes often employ intermediate steps to transform optical coherences to spin coherences for longer storage times. We analyze a scheme that uses three identical chirped control pulses for coherence rephasing in an inhomogeneously broadened ensemble of three-level Λ systems. The pulses induce a cyclic permutation of the atomic populations in the adiabatic regime. Optical coherences created by a signal pulse are stored as spin coherences at an intermediate time interval, and are rephased for echo emission when the ensemble is returned to the initial state. Echo emission during a possible partial rephasing when the medium is inverted can be suppressed with an appropriate choice of control pulse wave vectors. We demonstrate that the scheme works in an optically dense ensemble, despite control pulse distortions during propagation. It integrates conveniently the spin-wave storage step into memory schemes based on a second rephasing of the atomic coherences.

Performance analysis and optimization of high capacity pulse tube refrigerator

NASA Astrophysics Data System (ADS)

Ghahremani, Amir R.; Saidi, M. H.; Jahanbakhshi, R.; Roshanghalb, F.

High capacity pulse tube refrigerator (HCPTR) is a new generation of cryocoolers tailored to provide more than 250 W of cooling power at cryogenic temperatures. The most important characteristics of HCPTR when compared to other types of pulse tube refrigerators are a powerful pressure wave generator, and an accurate design. In this paper the influence of geometrical and operating parameters on the performance of a double inlet pulse tube refrigerator (DIPTR) is studied. The model is validated with the existing experimental data. As a result of this optimization, a new configuration of HCPTR is proposed. This configuration provides 335 W at 80 K cold end temperature with a frequency of 50 Hz and COP of 0.05.

Distortion of ultrashort pulses caused by aberrations

NASA Astrophysics Data System (ADS)

Horváth, Z. L.; Kovács, A. P.; Bor, Zs.

The effect of the primary wave aberrations (spherical aberration, astigmatism and coma) on ultrashort pulses is studied by the Nijboer-Zernike theory. The results of the geometrical and the wave optical treatments are compared.

Study on the Depth, Rate, Shape, and Strength of Pulse with Cardiovascular Simulator.

PubMed

Lee, Ju-Yeon; Jang, Min; Shin, Sang-Hoon

2017-01-01

Pulse diagnosis is important in oriental medicine. The purpose of this study is explaining the mechanisms of pulse with a cardiovascular simulator. The simulator is comprised of the pulse generating part, the vessel part, and the measurement part. The pulse generating part was composed of motor, slider-crank mechanism, and piston pump. The vessel part, which was composed with the aorta and a radial artery, was fabricated with silicon to implement pulse wave propagation. The pulse parameters, such as the depth, rate, shape, and strength, were simulated. With changing the mean pressure, the floating pulse and the sunken pulse were generated. The change of heart rate generated the slow pulse and the rapid pulse. The control of the superposition time of the reflected wave generated the string-like pulse and the slippery pulse. With changing the pulse pressure, the vacuous pulse and the replete pulse were generated. The generated pulses showed good agreements with the typical pulses.

Application of acoustic surface wave technology to shuttle radar

NASA Technical Reports Server (NTRS)

1975-01-01

The application of surface acoustic wave (SAW) signal processing devices in the space shuttle was explored. In order to demonstrate the functions which a SAW device might perform, a breadboard pulse compression filter (PCF) module was assembled. The PCF permits a pulse radar to operate with a large duty cycle and low peak power, a regime favorable to the use of solid state RF sources. The transducer design, strong coupling compensation, circuit model analysis, fabrication limitations, and performance evaluation of a PCF are described. The nominal value of the compression ratio is 100:1 with 10-MHz bandwidth centered at 60 MHz and 10-microsecond dispersive delay. The PCF incorporates dispersive interdigital transducers and a piezoelectric lithium niobate substrate.

Perturbing laser field dependent high harmonic phase modulations

NASA Astrophysics Data System (ADS)

Li, Zhengyan; Kong, Fanqi; Brown, Graham; Hammond, TJ; Ko, Dong-Hyuk; Zhang, Chunmei; Corkum, P. B.

2018-06-01

A perturbing laser pulse modulates and controls the phase of the high harmonic radiation driven by an intense fundamental pulse. Thus, a structured wave front can impress a specific spatial phase onto the generated high harmonic wave front. This modulation procedure leads to all-optical spatial light modulators for VUV or XUV radiation created by high harmonic generation. Here, through theoretical analysis and experiment, we study the correlation between the high harmonic phase modulations and the perturbing laser field amplitude and phase, providing guidelines for practical high harmonic spatial light modulators. In addition, we show that the petahertz optical oscilloscope for measuring electric fields of a perturbing beam is most robust using low order harmonics, far from the cut-off.

Evaluation of agreement between temporal series obtained from electrocardiogram and pulse wave.

NASA Astrophysics Data System (ADS)

Leikan, GM; Rossi, E.; Sanz, MCuadra; Delisle Rodríguez, D.; Mántaras, MC; Nicolet, J.; Zapata, D.; Lapyckyj, I.; Siri, L. Nicola; Perrone, MS

2016-04-01

Heart rate variability allows to study the cardiovascular autonomic nervous system modulation. Usually, this signal is obtained from the electrocardiogram (ECG). A simpler method for recording the pulse wave (PW) is by means of finger photoplethysmography (PPG), which also provides information about the duration of the cardiac cycle. In this study, the correlation and agreement between the time series of the intervals between heartbeats obtained from the ECG with those obtained from the PPG, were studied. Signals analyzed were obtained from young, healthy and resting subjects. For statistical analysis, the Pearson correlation coefficient and the Bland and Altman limits of agreement were used. Results show that the time series constructed from the PW would not replace the ones obtained from ECG.

Monte Carlo simulation of wave sensing with a short pulse radar

NASA Technical Reports Server (NTRS)

Levine, D. M.; Davisson, L. D.; Kutz, R. L.

1977-01-01

A Monte Carlo simulation is used to study the ocean wave sensing potential of a radar which scatters short pulses at small off-nadir angles. In the simulation, realizations of a random surface are created commensurate with an assigned probability density and power spectrum. Then the signal scattered back to the radar is computed for each realization using a physical optics analysis which takes wavefront curvature and finite radar-to-surface distance into account. In the case of a Pierson-Moskowitz spectrum and a normally distributed surface, reasonable assumptions for a fully developed sea, it has been found that the cumulative distribution of time intervals between peaks in the scattered power provides a measure of surface roughness. This observation is supported by experiments.

Method of estimating pulse response using an impedance spectrum

DOEpatents

Morrison, John L; Morrison, William H; Christophersen, Jon P; Motloch, Chester G

2014-10-21

Electrochemical Impedance Spectrum data are used to predict pulse performance of an energy storage device. The impedance spectrum may be obtained in-situ. A simulation waveform includes a pulse wave with a period greater than or equal to the lowest frequency used in the impedance measurement. Fourier series coefficients of the pulse train can be obtained. The number of harmonic constituents in the Fourier series are selected so as to appropriately resolve the response, but the maximum frequency should be less than or equal to the highest frequency used in the impedance measurement. Using a current pulse as an example, the Fourier coefficients of the pulse are multiplied by the impedance spectrum at corresponding frequencies to obtain Fourier coefficients of the voltage response to the desired pulse. The Fourier coefficients of the response are then summed and reassembled to obtain the overall time domain estimate of the voltage using the Fourier series analysis.

Single-cycle powerful megawatt to gigawatt terahertz pulse radiated from a wavelength-scale plasma oscillator

NASA Astrophysics Data System (ADS)

Wu, Hui-Chun; Sheng, Zheng-Ming; Zhang, Jie

2008-04-01

We propose a scheme to generate single-cycle powerful terahertz (THz) pulses by ultrashort intense laser pulses obliquely incident on an underdense plasma slab of a few THz wavelengths in thickness. THz waves are radiated from a transient net current driven by the laser ponderomotive force in the plasma slab. Analysis and particle-in-cell simulations show that such a THz source is capable of providing power of megawatts to gigawatts, field strength of MV/cm-GV/cm, and broad tunability range, which is potentially useful for nonlinear and high-field THz science and applications.

Terahertz imaging systems: a non-invasive technique for the analysis of paintings

NASA Astrophysics Data System (ADS)

Fukunaga, K.; Hosako, I.; Duling, I. N., III; Picollo, M.

2009-07-01

Terahertz (THz) imaging is an emerging technique for non-invasive analysis. Since THz waves can penetrate opaque materials, various imaging systems that use THz waves have been developed to detect, for instance, concealed weapons, illegal drugs, and defects in polymer products. The absorption of THz waves by water is extremely strong, and hence, THz waves can be used to monitor the water content in various objects. THz imaging can be performed either by transmission or by reflection of THz waves. In particular, time domain reflection imaging uses THz pulses that propagate in specimens, and in this technique, pulses reflected from the surface and from the internal boundaries of the specimen are detected. In general, the internal structure is observed in crosssectional images obtained using micro-specimens taken from the work that is being analysed. On the other hand, in THz time-domain imaging, a map of the layer of interest can be easily obtained without collecting any samples. When realtime imaging is required, for example, in the investigation of the effect of a solvent or during the monitoring of water content, a THz camera can be used. The first application of THz time-domain imaging in the analysis of a historical tempera masterpiece was performed on the panel painting Polittico di Badia by Giotto, of the permanent collection of the Uffizi Gallery. The results of that analysis revealed that the work is composed of two layers of gypsum, with a canvas between these layers. In the paint layer, gold foils covered by paint were clearly observed, and the consumption or ageing of gold could be estimated by noting the amount of reflection. These results prove that THz imaging can yield useful information for conservation and restoration purposes.

Project Physics Programmed Instruction, Waves 1.

ERIC Educational Resources Information Center

Harvard Univ., Cambridge, MA. Harvard Project Physics.

This programmed instruction booklet is an interim version of instructional materials being developed by Harvard Project Physics. It is the first of two booklets on the topic of waves and covers pulses, how pulses travel, and what happens when two pulses pass through the same region at the same time. For the second booklet in this series, see SE…

Normal Pregnancy Is Associated with Changes in Central Hemodynamics and Enhanced Recruitable, but Not Resting, Endothelial Function

PubMed Central

Zócalo, Yanina; Farro, Ignacio; Farro, Federico; Scasso, Santiago; Bia, Daniel

2015-01-01

Introduction. Flow-mediated dilation (FMD), low flow-mediated constriction (L-FMC), and reactive hyperemia-related changes in carotid-to-radial pulse wave velocity (ΔPWVcr%) could offer complementary information about both “recruitability” and “resting” endothelial function (EF). Carotid-to-femoral pulse wave velocity (PWVcf) and pulse wave analysis-derived parameters (i.e., AIx@75) are the gold standard methods for noninvasive evaluation of aortic stiffness and central hemodynamics. If healthy pregnancy is associated with both changes in resting and recruitable EF, as well as in several arterial parameters, it remains unknown and/or controversial. Objectives. To simultaneously and noninvasively assess in healthy pregnant (HP) and nonpregnant (NP) women central parameters in conjunction with “basal and recruitable” EF, employing new complementary approaches. Methods. HP (n = 11, 34.2 ± 3.3 weeks of gestation) and age- and cardiovascular risk factors-matched NP (n = 22) were included. Aortic blood pressure (BP), AIx@75, PWVcf, common carotid stiffness, and intima-media thickness, as well as FMD, L-FMC, and ΔPWVcr %, were measured. Results. Aortic BP, stiffness, and AIx@75 were reduced in HP. ΔPWVcr% and FMD were enhanced in HP in comparison to NP. No differences were found in L-FMC between groups. Conclusion. HP is associated with reduced aortic stiffness, central BP, wave reflections, and enhanced recruitable, but not resting, EF. PMID:26421317

Doubly-excited pulse-waves on flowing liquid films: experiments and numerical simulations

NASA Astrophysics Data System (ADS)

Adebayo, Idris; Xie, Zhihua; Che, Zhizhao; Wray, Alex; Matar, Omar

2016-11-01

The interaction patterns between doubly-excited pulse waves on a flowing liquid film are studied both experimentally and numerically. The flowing film is constituted on an inclined glass substrate while pulse-waves are excited on the film surface by means of a solenoid valve connected to a relay which receives signals from customised Matlab routines. The effect of varying the system parameters i.e. film flow rate, inter-pulse interval and substrate inclination angle on the pulse interaction patterns are then studied. Results show that different interaction patterns exist for these binary pulses; which include a singular behaviour, complete merger, partial merger and total non-coalescence. A regime map of these patterns is then plotted for each inclination angles examined, based on the film Re and the inter-pulse interval. Finally, the individual effect of the system parameters on the merging distance of these binary pulses in the merger mode is then studied and the results validated using both numerical simulations and mathematical modelling. Funding from the Nigerian Government (for Idris Adebayo), and the EPSRC through a programme Grant MEMPHIS (EP/K003976/1) gratefully acknowledged.

Focusing of shock waves induced by optical breakdown in water

PubMed Central

Sankin, Georgy N.; Zhou, Yufeng; Zhong, Pei

2008-01-01

The focusing of laser-generated shock waves by a truncated ellipsoidal reflector was experimentally and numerically investigated. Pressure waveform and distribution around the first (F1) and second foci (F2) of the ellipsoidal reflector were measured. A neodymium doped yttrium aluminum garnet laser of 1046 nm wavelength and 5 ns pulse duration was used to create an optical breakdown at F1, which generates a spherically diverging shock wave with a peak pressure of 2.1–5.9 MPa at 1.1 mm stand-off distance and a pulse width at half maximum of 36–65 ns. Upon reflection, a converging shock wave is produced which, upon arriving at F2, has a leading compressive wave with a peak pressure of 26 MPa and a zero-crossing pulse duration of 0.1 μs, followed by a trailing tensile wave of −3.3 MPa peak pressure and 0.2 μs pulse duration. The −6 dB beam size of the focused shock wave field is 1.6×0.2 mm2 along and transverse to the shock wave propagation direction. Formation of elongated plasmas at high laser energy levels limits the increase in the peak pressure at F2. General features in the waveform profile of the converging shock wave are in qualitative agreement with numerical simulations based on the Hamilton model. PMID:18537359

Design and analysis of coherent OCDM en/decoder based on photonic crystal

NASA Astrophysics Data System (ADS)

Zhang, Chongfu; Qiu, Kun

2008-08-01

The design and performance analysis of a new coherent optical en/decoder based on photonic crystal (PhC) for optical code -division -multiple (OCDM) are presented in this paper. In this scheme, the optical pulse phase and time delay can be flexibly controlled by photonic crystal phase shifter and time delayer by using the appropriate design of fabrication. According to the PhC transmission matrix theorem, combination calculation of the impurity and normal period layers is applied, and performances of the PhC-based optical en/decoder are also analyzed. The reflection, transmission, time delay characteristic and optical spectrum of pulse en/decoded are studied for the waves tuned in the photonic band-gap by numerical calculation. Theoretical analysis and numerical results indicate that the optical pulse is achieved to properly phase modulation and time delay, and an auto-correlation of about 8 dB ration and cross-correlation is gained, which demonstrates the applicability of true pulse phase modulation in a number of applications.

[Application of the mixed programming with Labview and Matlab in biomedical signal analysis].

PubMed

Yu, Lu; Zhang, Yongde; Sha, Xianzheng

2011-01-01

This paper introduces the method of mixed programming with Labview and Matlab, and applies this method in a pulse wave pre-processing and feature detecting system. The method has been proved suitable, efficient and accurate, which has provided a new kind of approach for biomedical signal analysis.

Shock-Wave Pulse Compression and Stretching of Dodecane and Mineral Oils

NASA Astrophysics Data System (ADS)

Bannikova, I. A.; Zubareva, A. N.; Utkin, A. V.

2018-04-01

The behavior of dodecane, vacuum, and transformer oils under shock-wave pulse compression and stretching are studied experimentally. The wave profiles are registered using a VISAR laser interferometer. The shock adiabats, the dependence of the sound velocity on the pressure, and the maximum negative pressures developed in the studied liquids are determined. It is shown that the negative pressure value does not depend on the deformation rate in the case of oils and is a strong function of the compression pulse amplitude in the case of dodecane.

Of dipole antennas in a magnetized plasma in the resonance frequency band

NASA Astrophysics Data System (ADS)

Shirokov, E. A.; Chugunov, Yu. V.

2011-12-01

We consider characteristics of slow quasielectrostatic waves excited in the resonance frequency band by a source whose dimensions are much less than the wavelength of the electromagnetic wave. We primarily focus on the analysis of the radiation of a harmonic wave in pulsed mode by a dipole source. Firstly, we study the influence of electromagnetic, dispersive, and collisional corrections in the dispersion relation on the field shape. Secondly, we analyze the field structure near the resonance cone. In particular, the effects of the group delay and anomalous spreading of the wave are considered. The developed theory is used to interpret the "OEDIPUS-C" experiment. For example, a delay of 10-4 s and a significant (severalfold) spreading of the pulse were observed at a distance of about ten wavelengths. Finally, some aspects of the inverse problem of electrodynamics are examined. Namely, the role of the smoothness of the antenna charge distribution in the field structure formation is shown and a class of smooth charge distributions creating a given field structure is found.

Energy scaling and extended tunability of terahertz wave parametric oscillator with MgO-doped near-stoichiometric LiNbO₃ crystal.

PubMed

Wang, Yuye; Tang, Longhuang; Xu, Degang; Yan, Chao; He, Yixin; Shi, Jia; Yan, Dexian; Liu, Hongxiang; Nie, Meitong; Feng, Jiachen; Yao, Jianquan

2017-04-17

A widely tunable, high-energy terahertz wave parametric oscillator based on 1 mol. % MgO-doped near-stoichiometric LiNbO₃ crystal has been demonstrated with 1064 nm nanosecond pulsed laser pumping. The tunable range of 1.16 to 4.64 THz was achieved. The maximum THz wave output energy of 17.49 μJ was obtained at 1.88 THz under the pump energy of 165 mJ/pulse, corresponding to the THz wave conversion efficiency of 1.06 × 10^-4 and the photon conversion efficiency of 1.59%, respectively. Moreover, under the same experimental conditions, the THz output energy of TPO with MgO:SLN crystal was about 2.75 times larger than that obtained from the MgO:CLN TPO at 1.60 THz. Based on the theoretical analysis, the THz energy enhancement mechanism in the MgO:SLN TPO was clarified to originate from its larger Raman scattering cross section and smaller absorption coefficient.

The Diagnostic Value of Pulsed Wave Tissue Doppler Imaging in Asymptomatic Beta- Thalassemia Major Children and Young Adults; Relation to Chemical Biomarkers of Left Ventricular Function and Iron Overload

PubMed Central

Ragab, Seham M; Fathy, Waleed M; El-Aziz, Walaa FAbd; Helal, Rasha T

2015-01-01

Background Cardiac iron toxicity is the leading cause of death among β-halassaemia major (TM) patients. Once heart failure becomes overt, it is difficult to reverse. Objectives To investigate non-overt cardiac dysfunctions in TM patients using pulsed wave Tissue Doppler Imaging (TD I) and its relation to iron overload and brain natriuretic peptide (BNP). Methods Thorough clinical, conventional echo and pulsed wave TDI parameters were compared between asymptomatic 25 β-TM patients and 20 age and gender matched individuals. Serum ferritin and plasma BNP levels were assayed by ELISA. Results TM patients had significant higher mitral inflow early diastolic (E) wave and non significant other conventional echo parameters. In the patient group, pulsed wave TDI revealed systolic dysfunctions, in the form of significant higher isovolumetric contraction time (ICT), and lower ejection time (E T), with diastolic dysfunction in the form of higher isovolumetric relaxation time (IRT), and lower mitral annulus early diastolic velocity E′ (12.07 ±2.06 vs 15.04±2.65, P= 0.003) compared to the controls. Plasma BNP was higher in patients compared to the controls. Plasma BNP and serum ferritin had a significant correlation with each other and with pulsed wave conventional and TDI indices of systolic and diastolic functions. Patients with E/E′ ≥ 8 had significant higher serum ferritin and plasma BNP levels compared to those with ratio < 8 without a difference in Hb levels. Conclusion Pulsed wave TDI is an important diagnostic tool for latent cardiac dysfunction in iron-loaded TM patients and is related to iron overload and BNP. PMID:26401240

The Diagnostic Value of Pulsed Wave Tissue Doppler Imaging in Asymptomatic Beta- Thalassemia Major Children and Young Adults; Relation to Chemical Biomarkers of Left Ventricular Function and Iron Overload.

PubMed

Ragab, Seham M; Fathy, Waleed M; El-Aziz, Walaa FAbd; Helal, Rasha T

2015-01-01

Cardiac iron toxicity is the leading cause of death among β-halassaemia major (TM) patients. Once heart failure becomes overt, it is difficult to reverse. To investigate non-overt cardiac dysfunctions in TM patients using pulsed wave Tissue Doppler Imaging (TD I) and its relation to iron overload and brain natriuretic peptide (BNP). Thorough clinical, conventional echo and pulsed wave TDI parameters were compared between asymptomatic 25 β-TM patients and 20 age and gender matched individuals. Serum ferritin and plasma BNP levels were assayed by ELISA. TM patients had significant higher mitral inflow early diastolic (E) wave and non significant other conventional echo parameters. In the patient group, pulsed wave TDI revealed systolic dysfunctions, in the form of significant higher isovolumetric contraction time (ICT), and lower ejection time (E T), with diastolic dysfunction in the form of higher isovolumetric relaxation time (IRT), and lower mitral annulus early diastolic velocity E' (12.07 ±2.06 vs 15.04±2.65, P= 0.003) compared to the controls. Plasma BNP was higher in patients compared to the controls. Plasma BNP and serum ferritin had a significant correlation with each other and with pulsed wave conventional and TDI indices of systolic and diastolic functions. Patients with E/E' ≥ 8 had significant higher serum ferritin and plasma BNP levels compared to those with ratio < 8 without a difference in Hb levels. Pulsed wave TDI is an important diagnostic tool for latent cardiac dysfunction in iron-loaded TM patients and is related to iron overload and BNP.

A two-dimensional analysis of the sensitivity of a pulse first break to wave speed contrast on a scale below the resolution length of ray tomography.

PubMed

Willey, Carson L; Simonetti, Francesco

2016-06-01

Mapping the speed of mechanical waves traveling inside a medium is a topic of great interest across many fields from geoscience to medical diagnostics. Much work has been done to characterize the fidelity with which the geometrical features of the medium can be reconstructed and multiple resolution criteria have been proposed depending on the wave-matter interaction model used to decode the wave speed map from scattering measurements. However, these criteria do not define the accuracy with which the wave speed values can be reconstructed. Using two-dimensional simulations, it is shown that the first-arrival traveltime predicted by ray theory can be an accurate representation of the arrival of a pulse first break even in the presence of diffraction and other phenomena that are not accounted for by ray theory. As a result, ray-based tomographic inversions can yield accurate wave speed estimations also when the size of a sound speed anomaly is smaller than the resolution length of the inversion method provided that traveltimes are estimated from the signal first break. This increased sensitivity however renders the inversion more susceptible to noise since the amplitude of the signal around the first break is typically low especially when three-dimensional anomalies are considered.

Proposal and performance analysis on the PDM microwave photonic link for the mm-wave signal with hybrid QAM-MPPM-RZ modulation

NASA Astrophysics Data System (ADS)

Tian, Bo; Zhang, Qi; Ma, Jianxin; Tao, Ying; Shen, Yufei; Wang, Yang; Zhang, Geng; Zhou, Wenmao; Zhao, Yi; Pan, Xiaolong

2018-07-01

A polarization division multiplexed (PDM) microwave photonic link for the millimeter (MM)-wave signal with hybrid modulation scheme is proposed in this paper, which is based on the combination of quadrature amplitude modulation, multi-pulse pulse-position modulation and return to zero modulation (QAM-MPPM-RZ). In this scheme, the two orthogonal polarization states enable simultaneous transmission of four data flows, which can provide different services for users according to the data rate requirement. To generate hybrid QAM-MPPM-RZ mm-wave signal, the QAM mm-wave signal is directly modulated by MPPM-RZ signal without using digital signal processing (DSP) devices, which reduces the overhead of the encoding process. Then, the generated QAM-MPPM-RZ mm-wave signal is transmitted in PDM microwave photonic link based on SSB modulation. The sparsity characteristic of QAM-MPPM-RZ not only improves the power efficiency, but also decreases the degradation caused by the fiber chromatic dispersion. The simulation results show that, under the constraint of the same transmitted data rate, the PDM microwave photonic link with 50 GHz QAM-MPPM-RZ mm-wave signal achieves much lower levels of bit-error rate than ordinary 32-QAM. In addition, the increase of laser linewidth brings no additional impact to the proposed scheme.

Liberation of a pinned spiral wave by a rotating electric pulse

NASA Astrophysics Data System (ADS)

Chen, Jiang-Xing; Peng, Liang; Ma, Jun; Ying, He-Ping

2014-08-01

Spiral waves may be pinned to anatomical heterogeneities in the cardiac tissue, which leads to monomorphic ventricular tachycardia. Wave emission from heterogeneities (WEH) induced by electric pulses in one direction (EP) is a promising method for liberating such waves by using heterogeneities as internal virtual pacing sites. Here, based on the WEH effect, a new mechanism of liberation by means of a rotating electric pulse (REP) is proposed in a generic model of excitable media. Compared with the EP, the REP has the advantage of opening wider time window to liberate pinned spiral. The influences of rotating direction and frequency of the REP, and the radius of the obstacles on this new mechanism are studied. We believe this strategy may improve manipulations with pinned spiral waves in heart experiments.

Large-amplitude acoustic solitary waves in a Yukawa chain

NASA Astrophysics Data System (ADS)

Sheridan, T. E.; Gallagher, James C.

2017-06-01

We experimentally study the excitation and propagation of acoustic solitary waves in a one-dimensional dusty plasma (i.e. a Yukawa chain) with particles interacting through a screened Coulomb potential. The lattice constant mm. Waves are launched by applying a 100 mW laser pulse to one end of the chain for laser pulse durations from 0.10 to 2.0 s. We observe damped solitary waves which propagate for distances with an acoustic speed s=11.5\\pm 0.2~\\text{mm}~\\text{s}-1$ . The maximum velocity perturbation increases with laser pulse duration for durations s and then saturates at . The wave speed is found to be independent of the maximum amplitude, indicating that the formation of nonlinear solitons is prevented by neutral-gas damping.

A method for calculating transient thrust and flow-rate levels for Mariner type attitude control nitrogen gas jets

NASA Technical Reports Server (NTRS)

Ferrera, J. D.

1972-01-01

The purpose of this report is to define and program the transient pneumatic flow equations necessary to determine, for a given set of conditions (geometry, pressures, temperatures, valve on time, etc.), the total nitrogen impulse and mass flow per pulse for the single pulsing of a Mariner type reaction control assembly valve. The rates of opening and closing of the valves are modeled, and electrical pulse durations from 20 to 100 ms are investigated. In developing the transient flow analysis, maximum use was made of the steady-state analysis. The impulse results are also compared to an equivalent square-wave impulse for both the Mariner Mars 1971 (MM'71) and Mariner Mars 1964 (MM'64) systems. It is demonstrated that, whereas in the MM'64 system, the actual impulse was as much as 56 percent higher than an assumed impulse (which is the product of the steady-state thrust and value on time i.e., the square wave), in the MM'71 system, these two values were in error in the same direction by only approximately 4 percent because of the larger nozzle areas and shorter valve stroke used.

The scattering of electromagnetic pulses by a slit in a conducting screen

NASA Technical Reports Server (NTRS)

Ackerknecht, W. E., III; Chen, C.-L.

1975-01-01

A direct method for calculating the impulse response of a slit in a conducting screen is presented which is derived specifically for the analysis of transient scattering by two-dimensional objects illuminated by a plane incident wave. The impulse response is obtained by assuming that the total response is composed of two sequences of diffracted waves. The solution is determined for the first two waves in one sequence by using Green's functions and the equivalence principle, for additional waves in the sequence by iteration, and for the other sequence by a transformation of coordinates. The cases of E-polarization and H-polarization are considered.

The Use of Steady and Unsteady Detonation Waves for Propulsion Systems

NASA Technical Reports Server (NTRS)

Adelman, Henry G.; Menees, Gene P.; Cambier, Jean-Luc; Bowles, Jeffrey V.; Cavolowsky, John A. (Technical Monitor)

1995-01-01

Detonation wave enhanced supersonic combustors such as the Oblique Detonation Wave Engine (ODWE) are attractive propulsion concepts for hypersonic flight. These engines utilize detonation waves to enhance fuel-air mixing and combustion. The benefits of wave combustion systems include shorter and lighter engines which require less cooling and generate lower internal drag. These features allow air-breathing operation at higher Mach numbers than the diffusive burning scramjet delaying the need for rocket engine augmentation. A comprehensive vehicle synthesis code has predicted the aerodynamic characteristics and structural size and weight of a typical single-stage-to-orbit vehicle using an ODWE. Other studies have focused on the use of unsteady or pulsed detonation waves. For low speed applications, pulsed detonation engines (PDE) have advantages in low weight and higher efficiency than turbojets. At hypersonic speeds, the pulsed detonations can be used in conjunction with a scramjet type engine to enhance mixing and provide thrust augmentation.

Pulse wave velocity in patients with severe head injury a pilot study.

PubMed

Shahsavari, S; McKelvey, T; Rydenhag, B; Ritzén, C Eriksson

2010-01-01

The study aimed to determine the potential of pulse wave velocity measurements to reflect changes in compliant cerebral arteries/arterioles in head injured patients. The approach utilizes the electrocardiogram and intracranial pressure signals to measure the wave transit time between heart and cranial cavity. Thirty five clinical records of nineteen head injured patients, with different levels of cerebrovascular pressure-reactivity response, were investigated through the study. Results were compared with magnitude of normalized transfer function at the fundamental cardiac frequency. In patients with intact cerebrovascular pressure-reactivity, magnitude of normalized transfer function at the fundamental cardiac component was found to be highly correlated with pulse wave transit time.

Whistler mode plasma waves observed on Electron Echo 2

NASA Technical Reports Server (NTRS)

Monson, S. J.; Kellogg, P. J.; Cartwright, D. G.

1976-01-01

Observations of whistler-mode waves associated with beams of electrons injected into the ionosphere are reported. The measurements are from the plasma-wave experiments carried on the Electron Echo 2 sounding rocket launched on September 24, 1972. Over 2000 electron injections were made with durations of 8 ms and 64 ms and pitch angles from 0 to 180 deg. The electric field receivers carried on the ejected nose cone observed strong whistler waves in the range from less than 100 kHz up to the electron cyclotron frequency of 1400 kHz. The whistler characteristics fall into four distinct types depending on pitch angle and gun energy. Both frequency and amplitude showed strong dependence on time from the start of the pulse and pitch angle. Cases of enhancement at the leading edge of a gun pulse, growth during a pulse, and echoes after the end of a pulse were all observed.

A differential optical interferometer for measuring short pulses of surface acoustic waves.

PubMed

Shaw, Anurupa; Teyssieux, Damien; Laude, Vincent

2017-09-01

The measurement of the displacements caused by the propagation of a short pulse of surface acoustic waves on a solid substrate is investigated. A stabilized time-domain differential interferometer is proposed, with the surface acoustic wave (SAW) sample placed outside the interferometer. Experiments are conducted with surface acoustic waves excited by a chirped interdigital transducer on a piezoelectric lithium niobate substrate having an operational bandwidth covering the 200-400MHz frequency range and producing 10-ns pulses with 36nm maximum out-of-plane displacement. The interferometric response is compared with a direct electrical measurement obtained with a receiving wide bandwidth interdigital transducer and good correspondence is observed. The effects of varying the path difference of the interferometer and the measurement position on the surface are discussed. Pulse compression along the chirped interdigital transducer is observed experimentally. Copyright © 2017 Elsevier B.V. All rights reserved.

Local pulse wave velocity estimated from small vibrations measured ultrasonically at multiple points on the arterial wall

NASA Astrophysics Data System (ADS)

Ito, Mika; Arakawa, Mototaka; Kanai, Hiroshi

2018-07-01

Pulse wave velocity (PWV) is used as a diagnostic criterion for arteriosclerosis, a major cause of heart disease and cerebrovascular disease. However, there are several problems with conventional PWV measurement techniques. One is that a pulse wave is assumed to only have an incident component propagating at a constant speed from the heart to the femoral artery, and another is that PWV is only determined from a characteristic time such as the rise time of the blood pressure waveform. In this study, we noninvasively measured the velocity waveform of small vibrations at multiple points on the carotid arterial wall using ultrasound. Local PWV was determined by analyzing the phase component of the velocity waveform by the least squares method. This method allowed measurement of the time change of the PWV at approximately the arrival time of the pulse wave, which discriminates the period when the reflected component is not contaminated.

High resolution data acquisition

DOEpatents

Thornton, G.W.; Fuller, K.R.

1993-04-06

A high resolution event interval timing system measures short time intervals such as occur in high energy physics or laser ranging. Timing is provided from a clock, pulse train, and analog circuitry for generating a triangular wave synchronously with the pulse train (as seen in diagram on patent). The triangular wave has an amplitude and slope functionally related to the time elapsed during each clock pulse in the train. A converter forms a first digital value of the amplitude and slope of the triangle wave at the start of the event interval and a second digital value of the amplitude and slope of the triangle wave at the end of the event interval. A counter counts the clock pulse train during the interval to form a gross event interval time. A computer then combines the gross event interval time and the first and second digital values to output a high resolution value for the event interval.

High resolution data acquisition

DOEpatents

Thornton, Glenn W.; Fuller, Kenneth R.

1993-01-01

A high resolution event interval timing system measures short time intervals such as occur in high energy physics or laser ranging. Timing is provided from a clock (38) pulse train (37) and analog circuitry (44) for generating a triangular wave (46) synchronously with the pulse train (37). The triangular wave (46) has an amplitude and slope functionally related to the time elapsed during each clock pulse in the train. A converter (18, 32) forms a first digital value of the amplitude and slope of the triangle wave at the start of the event interval and a second digital value of the amplitude and slope of the triangle wave at the end of the event interval. A counter (26) counts the clock pulse train (37) during the interval to form a gross event interval time. A computer (52) then combines the gross event interval time and the first and second digital values to output a high resolution value for the event interval.

Numerical study of double-pulse laser ablation of Al

NASA Astrophysics Data System (ADS)

Förster, G. D.; Lewis, Laurent J.

2018-06-01

The effect of double laser pulses (DPs) on the ablation process in solids is studied using a hybrid two-temperature model combining a continuum description of the conduction band electrons with a classical molecular dynamics (MD) approach for the ions. The study is concerned with double pulses with delays in the range of 0-50 ps and absorbed laser fluences of 0.5, 1.0, and 1.5 J/m 2 [i.e., 1-3 times the ablation threshold for single-pulse ablation (SP)], taking Al as a generic example of simple metals. A detailed analysis, including the assessment of thermodynamic pathways and cavitation rates, leads to a comprehensive picture of the mechanisms active during the different stages of the ablation process initiated by DPs. This study provides an explanation for several phenomena observed in DP ablation experiments. In particular, with respect to SP ablation, crater depths are reduced, which can be explained by the compensation of the rarefaction wave from the first laser pulse with the compression wave from the second pulse, or, at higher fluences and larger delays, by the fact that the target surface is shielded with matter ablated by the first laser pulse. Also, we discuss how smoother surface structures obtained using DPs may be related to features found in the simulations—viz., reduced mechanical strain and peak lattice temperatures. Finally, vaporization appears to be enhanced in DP ablation, which may improve the resolution of emission spectra.

Polarization-operator approach to optical signatures of axion-like particles in strong laser pulses

NASA Astrophysics Data System (ADS)

Villalba-Chávez, S.; Podszus, T.; Müller, C.

2017-06-01

Hypothetical oscillations of probe photons into axion-like particles might be revealed by exploiting the strong fields of high-intensity laser pulses. Considering an arbitrary plane-wave background, we determine the polarization tensor induced by the quantum fluctuations of the axion field and use it to calculate how the polarimetric properties of an initially linear-polarized probe beam are modified. We find that various experimental setups based on contemporary facilities and instrumentation might lead to new exclusion bounds on the parameter space of these particle candidates. The impact of the pulse shape on the discovery potential is studied via a comparison between the cases in which the wave is modulated by a Gaussian envelope and a sin2 profile. This analysis shows that the upper limits resulting from the ellipticity are relatively insensitive to this change, whereas those arising from the rotation of the polarization plane turn out to be more dependent on the field shape.

Peripheral circulatory disorders in essential thrombocythemia.

PubMed

Małecki, Rafał; Gacka, Małgorzata; Fiodorenko-Dumas, Żanna; Dumas, Ilias; Kwiatkowski, Jacek; Adamiec, Rajmund; Kuliszkiewicz-Janus, Małgorzata

2018-03-01

A significant number of patients with essential thrombocythemia (ET) complain of symptoms including distal parts of the extremities (e.g., paresthesias or Raynaud's phenomenon). The aim of the present study was to examine peripheral circulation in the upper extremities of individuals with ET. The study included 45 ET patients and 30 control subjects. All participants were subjected to thermography, photoplethysmography, impedance plethysmography, and applanation tonometry pulse wave analysis. The patients with ET differed significantly from the control subjects in terms of 3rd finger skin temperature (mean 31.04 vs. 32.45°C), skin temperature gradient (mean 1.82 vs. 0.11°C), photoplethysmographic amplitude (median 0.25 vs. 0.74%), and pulse waveform in the radial artery (more frequent occurrence of type B waveform). Pulse wave parameters correlated with the skin temperature gradient. The study findings imply the altered regulation of peripheral circulation in ET, including a decreased flow and an increased resistance. Copyright © 2017 Elsevier Inc. All rights reserved.

Interplay between arterial stiffness and diastolic function: a marker of ventricular-vascular coupling.

PubMed

Zito, Concetta; Mohammed, Moemen; Todaro, Maria Chiara; Khandheria, Bijoy K; Cusmà-Piccione, Maurizio; Oreto, Giuseppe; Pugliatti, Pietro; Abusalima, Mohamed; Antonini-Canterin, Francesco; Vriz, Olga; Carerj, Scipione

2014-11-01

We evaluated the interplay between left ventricular diastolic function and large-artery stiffness in asymptomatic patients at increased risk of heart failure and no structural heart disease (Stage A). We divided 127 consecutive patients (mean age 49 ± 17 years) with risk factors for heart failure who were referred to our laboratory to rule out structural heart disease into two groups according to presence (Group 1, n = 35) or absence (Group 2, n = 92) of grade I left ventricular diastolic dysfunction. Doppler imaging with high-resolution echo-tracking software was used to measure intima-media thickness (IMT) and stiffness of carotid arteries. Group 1 had significantly higher mean age, blood pressure, left ventricular mass index, carotid IMT and arterial stiffness than Group 2 (P < 0.05). Overall, carotid stiffness indices (β-stiffness index, augmentation index and elastic modulus) and 'one-point' pulse wave velocity each showed inverse correlation with E-wave velocity, E' velocity and E/A ratio, and direct correlation with A-wave velocity, E-wave deceleration time and E/E' ratio (P < 0.05). Arterial compliance showed negative correlations with the echocardiographic indices of left ventricular diastolic function (P < 0.05). On logistic regression analysis, age, hypertension, SBP, pulse pressure, left ventricular mass index, carotid IMT and stiffness parameters were associated with grade I left ventricular diastolic dysfunction (P < 0.05 for each). However, on multivariate logistic analysis, only 'one-point' pulse wave velocity and age were independent predictors (P = 0.038 and P = 0.016, respectively). An independent association between grade I left ventricular diastolic dysfunction and increased arterial stiffness is demonstrated at the earliest stage of heart failure. Hence, assessment of vascular function, beyond cardiac function, should be included in a comprehensive clinical evaluation of these patients.

A comparison between the pathophysiology of multiple sclerosis and normal pressure hydrocephalus: is pulse wave encephalopathy a component of MS?

PubMed

Bateman, Grant A; Lechner-Scott, Jeannette; Lea, Rodney A

2016-09-22

It has been suggested there is a chronic neurodegenerative disorder, underlying the pathophysiology of multiple sclerosis (MS), which is distinct from the more obvious immune-mediated attack on the white matter. Limited data exists indicating there is an alteration in pulse wave propagation within the craniospinal cavity in MS, similar to the findings in normal pressure hydrocephalus (NPH). It is hypothesized MS may harbor pulse wave encephalopathy. The purpose of this study is to compare blood flow and pulse wave measurements in MS patients with a cohort of NPH patients and control subjects, to test this hypothesis. Twenty patients with MS underwent magnetic resonance (MR) flow quantification techniques. Mean blood flow and stroke volume were measured in the arterial inflow and venous out flow from the sagittal (SSS) and straight sinus (ST). The arteriovenous delay (AVD) was defined. The results were compared with both age-matched controls and NPH patients. In MS there was a 35 % reduction in arteriovenous delay and a 5 % reduction in the percentage of the arterial inflow returning via the sagittal sinus compared to age matched controls. There was an alteration in pulse wave propagation, with a 26 % increase in arterial stroke volume but 30 % reduction in SSS and ST stroke volume. The AVD and blood flow changes were in the same direction to those of NPH patients. There are blood flow and pulsation propagation changes in MS patients which are similar to those of NPH patients. The findings would be consistent with an underlying pulse wave encephalopathy component in MS.

Preliminary Examination of Pulse Shapes From GLAS Ocean Returns

NASA Astrophysics Data System (ADS)

Swift, T. P.; Minster, B.

2003-12-01

We have examined GLAS data collected over the Pacific ocean during the commission phase of the ICESat mission, in an area where sea state is well documented. The data used for this preliminary analysis were acquired during two passes along track 95, on March 18 and 26 of 2003, along the stretch offshore southern California. These dates were chosen for their lack of cloud cover; large (4.0 m) and small (0.7 m) significant wave heights, respectively; and the presence of waves emanating from single distant Pacific storms. Cloud cover may be investigated using MODIS images (http://acdisx.gsfc.nasa.gov/data/dataset/MODIS/), while models of significant wave heights and wave vectors for offshore California are archived by the Coastal Data Information Program (http://cdip.ucsd.edu/cdip_htmls/models.shtml). We find that the shape of deep-ocean GLAS pulse returns is diagnostic of the state of the ocean surface. A calm surface produces near-Gaussian, single-peaked shot returns. In contrast, a rough surface produces blurred shot returns which often feature multiple peaks; these peaks are typically separated by total path lengths on the order of one meter. Gaussian curves fit to rough-water returns are therefore less reliable and lead to greater measurement error; outliers in the ocean surface elevation product are mostly the result of poorly fit low-energy shot returns. Additionally, beat patterns and aliasing artifacts may arise from the sampling of deep-ocean wave trains by GLAS footprints separated by 140m. The apparent wavelength of such patterns depends not only on the wave frequency, but also on the angle between the ICESat ground track and the azimuth of the wave crests. We present a preliminary analysis of such patterns which appears to be consistent with a simple geometrical model.

Computational assessment of model-based wave separation using a database of virtual subjects.

PubMed

Hametner, Bernhard; Schneider, Magdalena; Parragh, Stephanie; Wassertheurer, Siegfried

2017-11-07

The quantification of arterial wave reflection is an important area of interest in arterial pulse wave analysis. It can be achieved by wave separation analysis (WSA) if both the aortic pressure waveform and the aortic flow waveform are known. For better applicability, several mathematical models have been established to estimate aortic flow solely based on pressure waveforms. The aim of this study is to investigate and verify the model-based wave separation of the ARCSolver method on virtual pulse wave measurements. The study is based on an open access virtual database generated via simulations. Seven cardiac and arterial parameters were varied within physiological healthy ranges, leading to a total of 3325 virtual healthy subjects. For assessing the model-based ARCSolver method computationally, this method was used to perform WSA based on the aortic root pressure waveforms of the virtual patients. Asa reference, the values of WSA using both the pressure and flow waveforms provided by the virtual database were taken. The investigated parameters showed a good overall agreement between the model-based method and the reference. Mean differences and standard deviations were -0.05±0.02AU for characteristic impedance, -3.93±1.79mmHg for forward pressure amplitude, 1.37±1.56mmHg for backward pressure amplitude and 12.42±4.88% for reflection magnitude. The results indicate that the mathematical blood flow model of the ARCSolver method is a feasible surrogate for a measured flow waveform and provides a reasonable way to assess arterial wave reflection non-invasively in healthy subjects. Copyright © 2017 Elsevier Ltd. All rights reserved.

Intracompartmental pressure as a predictor of intratesticular blood flow: a rat model.

PubMed

Watson, Matthew J; Bartkowski, Donald P; Nelson, Nathan C

2015-06-01

We identified an intratesticular pressure at which vascular flow would cease in a testicular compartment syndrome model, defining a critical vascular stop flow pressure. A total of 52 male Sprague Dawley® rats were used for the study. The testicle of each rat was delivered from the scrotum and size measurements were taken. An intracompartment pressure monitor needle was inserted into the testis to record basal intratesticular pressure. The monitor needle remained in the testicle for the duration of the procedure. Vascular flow within the testis was measured using a variable frequency linear ultrasound transducer with color flow and pulse wave Doppler modalities. Saline was infused through the compartment monitor in 5 mm Hg increments via a pressure infusion pump. Following each 5 mm Hg increase intratesticular vascular blood flow and velocities were recorded using color flow and pulse wave, respectively. Data collection proceeded until color flow images indicated a complete absence of flow within the testis. Using a paired t-test (p <0.0001), mean color flow stop flow pressure was 52.17 mm Hg (95% CI 49.57-54.77) and pulse wave stop flow pressure was 36.34 mm Hg (95% CI 33.90-38.77). Regression analysis of pulse wave vs color flow showed a slope of 0.6960 ± 0.09112, a y-intercept of 0.02427 ± 4.824 and an x-intercept of -0.03486. This is the first known study to characterize a stop flow pressure within the testicular parenchyma resulting from an increased intracompartmental pressure. Due to probe sensitivity limitations, color flow appears to provide the most precise mean pressure of occlusion of 52.17 mm Hg. Copyright © 2015 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

Experiment and analysis of shock waves radiated from pulse laser focusing in a gelatin gel

NASA Astrophysics Data System (ADS)

Nakamura, Nobuyuki; Ando, Keita

2017-11-01

A fundamental understanding of shock and bubble dynamics in human tissues is essential to laser application for medical purposes. Here, we experimentally study the dynamics of shock waves in viscoelastic media. A nanosecond laser pulse of wavelength at 532 nm and of energy up to 2.66 +/- 0.09 mJ was focused through a microscope objective lens (10 x, NA = 0.30) into a gel of gelatin concentration at 3 and 10 wt%; a shock wave and a bubble can be generated, respectively, by rapid expansion of the laser-induced plasma and local heat deposition after the plasma recombines. The shock propagation and the bubble growth were recorded by a ultra-high-speed camera at 100 Mfps. The shock evolution was determined by image analysis of the recording and the shock pressure in the near field was computed according to the Rankine-Hugoniot relation. The far-field pressure was measured by a hydrophone. In the poster, we will present the decay rate of the shock pressure in the near and far fields and examine viscous effects on the shock dynamics. The Research Grant of Keio Leading-edge Laboratory of Science & Technology.

Cavitation-based hydro-fracturing simulator

DOEpatents

Wang, Jy-An John; Wang, Hong; Ren, Fei; Cox, Thomas S.

2016-11-22

An apparatus 300 for simulating a pulsed pressure induced cavitation technique (PPCT) from a pressurized working fluid (F) provides laboratory research and development for enhanced geothermal systems (EGS), oil, and gas wells. A pump 304 is configured to deliver a pressurized working fluid (F) to a control valve 306, which produces a pulsed pressure wave in a test chamber 308. The pulsed pressure wave parameters are defined by the pump 304 pressure and control valve 306 cycle rate. When a working fluid (F) and a rock specimen 312 are included in the apparatus, the pulsed pressure wave causes cavitation to occur at the surface of the specimen 312, thus initiating an extensive network of fracturing surfaces and micro fissures, which are examined by researchers.

Single-cycle high-intensity electromagnetic pulse generation in the interaction of a plasma wakefield with regular nonlinear structures.

PubMed

Bulanov, S S; Esirkepov, T Zh; Kamenets, F F; Pegoraro, F

2006-03-01

The interaction of regular nonlinear structures (such as subcycle solitons, electron vortices, and wake Langmuir waves) with a strong wake wave in a collisionless plasma can be exploited in order to produce ultrashort electromagnetic pulses. The electromagnetic field of the nonlinear structure is partially reflected by the electron density modulations of the incident wake wave and a single-cycle high-intensity electromagnetic pulse is formed. Due to the Doppler effect the length of this pulse is much shorter than that of the nonlinear structure. This process is illustrated with two-dimensional particle-in-cell simulations. The considered laser-plasma interaction regimes can be achieved in present day experiments and can be used for plasma diagnostics.

Coherent control of ultrafast optical four-wave mixing with two-color {omega}-3{omega} laser pulses

DOE Office of Scientific and Technical Information (OSTI.GOV)

Serrat, Carles

2005-08-15

A theoretical investigation on the coherent control of optical transient four-wave mixing interactions in two-level systems with two intense few-cycle propagating laser pulses of central angular frequencies {omega} and 3{omega} is reported. By numerically solving the full Maxwell-Bloch equations beyond the slowly varying envelope and rotating-wave approximations in the time domain, the nonlinear coupling to the optical field at frequency 5{omega} is found to depend critically on the initial relative phase {phi} of the propagating pulses: the coupling is enhanced when the pulses interfere constructively in the center ({phi}=0), while it is nearly suppressed when they are out of phasemore » ({phi}={pi})« less

A program to calculate pulse transmission responses through transversely isotropic media

NASA Astrophysics Data System (ADS)

Li, Wei; Schmitt, Douglas R.; Zou, Changchun; Chen, Xiwei

2018-05-01

We provide a program (AOTI2D) to model responses of ultrasonic pulse transmission measurements through arbitrarily oriented transversely isotropic rocks. The program is built with the distributed point source method that treats the transducers as a series of point sources. The response of each point source is calculated according to the ray-tracing theory of elastic plane waves. The program could offer basic wave parameters including phase and group velocities, polarization, anisotropic reflection coefficients and directivity patterns, and model the wave fields, static wave beam, and the observed signals for pulse transmission measurements considering the material's elastic stiffnesses and orientations, sample dimensions, and the size and positions of the transmitters and the receivers. The program could be applied to exhibit the ultrasonic beam behaviors in anisotropic media, such as the skew and diffraction of ultrasonic beams, and analyze its effect on pulse transmission measurements. The program would be a useful tool to help design the experimental configuration and interpret the results of ultrasonic pulse transmission measurements through either isotropic or transversely isotropic rock samples.

Mechanisms of amplification of ultrashort electromagnetic pulses in gyrotron traveling wave tube with helically corrugated waveguide

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ginzburg, N. S., E-mail: ginzburg@appl.sci-nnov.ru; Zaslavsky, V. Yu.; Nizhny Novgorod State University, 23 Gagarin Ave., 603950 Nizhny Novgorod

A time-domain self consistent theory of a gyrotron traveling wave tube with a helically corrugated operating waveguide has been developed. Based on this model, the process of short pulse amplification was studied in regimes of grazing and intersection of the dispersion curves of the electromagnetic wave and the electron beam. In the first case, the possibility of amplification without pulse form distortion was demonstrated for the pulse spectrum width of the order of the gain bandwidth. In the second case, when the electrons' axial velocity was smaller than the wave's group velocity, it was shown that the slippage of themore » incident signal with respect to the electron beam provides feeding of the signal by “fresh” electrons without initial modulation. As a result, the amplitude of the output pulse can exceed the amplitude of its saturated value for the case of the grazing regime, and, for optimal parameters, the peak output power can be even larger than the kinetic power of the electron beam.« less

Narrow bandwidth detection of vibration signature using fiber lasers

DOEpatents

Moore, Sean; Soh, Daniel B.S.

2018-05-08

The various technologies presented herein relate to extracting a portion of each pulse in a series of pulses reflected from a target to facilitate determination of a Doppler-shifted frequency for each pulse and, subsequently, a vibration frequency for the series of pulses. Each pulse can have a square-wave configuration, whereby each pulse can be time-gated to facilitate discarding the leading edge and the trailing edge (and associated non-linear effects) of each pulse and accordingly, capture of the central portion of the pulse from which the Doppler-shifted frequency, and ultimately, the vibration frequency of the target can be determined. Determination of the vibration velocity facilitates identification of the target being in a state of motion. The plurality of pulses can be formed from a laser beam (e.g., a continuous wave), the laser beam having a narrow bandwidth.

Visible continuum pulses based on enhanced dispersive wave generation for endogenous fluorescence imaging.

PubMed

Cui, Quan; Chen, Zhongyun; Liu, Qian; Zhang, Zhihong; Luo, Qingming; Fu, Ling

2017-09-01

In this study, we demonstrate endogenous fluorescence imaging using visible continuum pulses based on 100-fs Ti:sapphire oscillator and a nonlinear photonic crystal fiber. Broadband (500-700 nm) and high-power (150 mW) continuum pulses are generated through enhanced dispersive wave generation by pumping femtosecond pulses at the anomalous dispersion region near zero-dispersion wavelength of high-nonlinear photonic crystal fibers. We also minimize the continuum pulse width by determining the proper fiber length. The visible-wavelength two-photon microscopy produces NADH and tryptophan images of mice tissues simultaneously. Our 500-700 nm continuum pulses support extending nonlinear microscopy to visible wavelength range that is inaccessible to 100-fs Ti:sapphire oscillators and other applications requiring visible laser pulses.

Pulsed voltage electrospray ion source and method for preventing analyte electrolysis

DOEpatents

Kertesz, Vilmos [Knoxville, TN; Van Berkel, Gary [Clinton, TN

2011-12-27

An electrospray ion source and method of operation includes the application of pulsed voltage to prevent electrolysis of analytes with a low electrochemical potential. The electrospray ion source can include an emitter, a counter electrode, and a power supply. The emitter can include a liquid conduit, a primary working electrode having a liquid contacting surface, and a spray tip, where the liquid conduit and the working electrode are in liquid communication. The counter electrode can be proximate to, but separated from, the spray tip. The power system can supply voltage to the working electrode in the form of a pulse wave, where the pulse wave oscillates between at least an energized voltage and a relaxation voltage. The relaxation duration of the relaxation voltage can range from 1 millisecond to 35 milliseconds. The pulse duration of the energized voltage can be less than 1 millisecond and the frequency of the pulse wave can range from 30 to 800 Hz.

Multi-operational tuneable Q-switched mode-locking Er fibre laser

NASA Astrophysics Data System (ADS)

Qamar, F. Z.

2018-01-01

A wavelength-spacing tuneable, Q-switched mode-locking (QML) erbium-doped fibre laser based on non-linear polarization rotation controlled by four waveplates and a cube polarizer is proposed. A mode-locked pulse train using two quarter-wave plates and a half-wave plate (HWP) is obtained first, and then an extra HWP is inserted into the cavity to produce different operation regimes. The evolutions of temporal and spectral dynamics with different orientation angles of the extra HWP are investigated. A fully modulated stable QML pulse train is observed experimentally. This is, to the author’s best knowledge, the first experimental work reporting QML operation without adding an extra saturable absorber inside the laser cavity. Multi-wavelength pulse laser operation, multi-pulse train continuous-wave mode-locking operation and pulse-splitting operations are also reported at certain HWP angles. The observed operational dynamics are interpreted as a mutual interaction of dispersion, non-linear effect and insertion loss. This work provides a new mechanism for fabricating cheap tuneable multi-wavelength lasers with QML pulses.

The wave-field from an array of periodic emitters driven simultaneously by a broadband pulse.

PubMed

Dixon, Steve; Hill, Samuel; Fan, Yichao; Rowlands, George

2013-06-01

The use of phased array methods are commonplace in ultrasonic applications, where controlling the variation of the phase between the narrowband emitters in an array facilitates beam steering and focusing of ultrasonic waves. An approach is presented here whereby emitters of alternating polarity arranged in a one-dimensional array are pulsed simultaneously, and have sufficiently wide, controlled bandwidth to emit a two-dimensional wave. This pulsed approach provides a rapid means of simultaneously covering a region of space with a wave-front, whereby any wave that scatters or reflects off a body to a detector will have a distinct arrival time and frequency. This is a general wave phenomenon with a potential application in radar, sonar, and ultrasound. The key result is that one can obtain a smooth, continuous wave-front emitted from the array, over a large solid angle, whose frequency varies as a function of angle to the array. Analytic and finite element models created to describe this phenomenon have been validated with experimental results using ultrasonic waves in metal samples.

Distribution of deuterium and hydrogen in Zr and Ti foil assemblies under the action of a pulsed deuterium high-temperature plasma

NASA Astrophysics Data System (ADS)

Bondarenko, G. G.; Volobuev, I. V.; Eriskin, A. A.; Kobzev, A. P.; Nikulin, V. Ya.; Peregudova, E. N.; Silin, P. V.; Borovitskaya, I. V.

2017-09-01

Deuteron and proton elastic recoil detection analysis is used to study the accumulation and redistribution of deuterium and hydrogen in assemblies of two high-pure zirconium or titanium foils upon pulsed action of high-temperature deuterium plasma (PHTDP) in a plasma-focus installation PF-4. It is noted that, under the action of PHTDP, an implanted deuterium and hydrogen gas impurity are redistributed in the irradiated foils in large depths, which are significantly larger than the deuterium ion free paths (at their maximum velocity to 108 cm/s). The observed phenomenon is attributed to the carrying out of implanted deuterium and hydrogen under the action of powerful shock waves formed in the metallic foils under the action of PHTDP and/or the acceleration of diffusion of deuterium and hydrogen atoms under the action of a compression-rarefaction shock wave at the shock wave front with the redistribution of deuterium and hydrogen to large depths.

On the elimination of pulse wave velocity in stroke volume determination from the ultralow-frequency displacement ballistocardiogram.

DOT National Transportation Integrated Search

1964-03-01

A hydrodynamic model of the systemic circulatory system was mounted on an ultralow-frequency ballistocardiograph (ULF-BCG). The relationship between stroke volume and ballistocardiographic amplitude was investigated for different pulse wave velocitie...

Information hiding and retrieval in Rydberg wave packets using half-cycle pulses

DOE Office of Scientific and Technical Information (OSTI.GOV)

Murray, J. M.; Pisharody, S. N.; Wen, H.

We demonstrate an information hiding and retrieval scheme with the relative phases between states in a Rydberg wave packet acting as the bits of a data register. We use a terahertz half-cycle pulse (HCP) to transfer phase-encoded information from an optically accessible angular momentum manifold to another manifold which is not directly accessed by our laser pulses, effectively hiding the information from our optical interferometric measurement techniques. A subsequent HCP acting on these wave packets reintroduces the information back into the optically accessible data register manifold which can then be read out.

Algal Cell Response to Pulsed Waved Stimulation and Its Application to Increase Algal Lipid Production

NASA Astrophysics Data System (ADS)

Savchenko, Oleksandra; Xing, Jida; Yang, Xiaoyan; Gu, Quanrong; Shaheen, Mohamed; Huang, Min; Yu, Xiaojian; Burrell, Robert; Patra, Prabir; Chen, Jie

2017-02-01

Generating renewable energy while sequestering CO2 using algae has recently attracted significant research attention, mostly directing towards biological methods such as systems biology, genetic engineering and bio-refining for optimizing algae strains. Other approaches focus on chemical screening to adjust culture conditions or culture media. We report for the first time the physiological changes of algal cells in response to a novel form of mechanical stimulation, or a pulsed wave at the frequency of 1.5 MHz and the duty cycle of 20%. We studied how the pulsed wave can further increase algal lipid production on top of existing biological and chemical methods. Two commonly used algal strains, fresh-water Chlorella vulgaris and seawater Tetraselmis chuii, were selected. We have performed the tests in shake flasks and 1 L spinner-flask bioreactors. Conventional Gravimetric measurements show that up to 20% increase for algal lipid could be achieved after 8 days of stimulation. The total electricity cost needed for the stimulations in a one-liter bioreactor is only one-tenth of a US penny. Gas liquid chromatography shows that the fatty acid composition remains unchanged after pulsed-wave stimulation. Scanning electron microscope results also suggest that pulsed wave stimulation induces shear stress and thus increases algal lipid production.

Traveling waves in a spatially-distributed Wilson-Cowan model of cortex: From fronts to pulses

NASA Astrophysics Data System (ADS)

Harris, Jeremy D.; Ermentrout, Bard

2018-04-01

Wave propagation in excitable media has been studied in various biological, chemical, and physical systems. Waves are among the most common evoked and spontaneous organized activity seen in cortical networks. In this paper, we study traveling fronts and pulses in a spatially-extended version of the Wilson-Cowan equations, a neural firing rate model of sensory cortex having two population types: Excitatory and inhibitory. We are primarily interested in the case when the local or space-clamped dynamics has three fixed points: (1) a stable down state; (2) a saddle point with stable manifold that acts as a threshold for firing; (3) an up state having stability that depends on the time scale of the inhibition. In the case when the up state is stable, we look for wave fronts, which transition the media from a down to up state, and when the up state is unstable, we are interested in pulses, a transient increase in firing that returns to the down state. We explore the behavior of these waves as the time and space scales of the inhibitory population vary. Some interesting findings include bistability between a traveling front and pulse, fronts that join the down state to an oscillation or spatiotemporal pattern, and pulses which go through an oscillatory instability.

Diffraction and quantum control of wave functions in nonresonant two-photon absorption

NASA Astrophysics Data System (ADS)

Li, Baihong; Pang, Huafeng; Wang, Doudou; Zhang, Tao; Dong, Ruifang; Li, Yongfang

2018-03-01

In this study, the nonresonant two-photon absorption process in a two-level atom, induced by a weak chirped pulse, is theoretically investigated in the frequency domain. An analytical expression of the wave function expressed by Fresnel functions is obtained, and the two-photon transition probability (TPTP) versus the integral bandwidth, spectral width, and chirp parameter is analyzed. The results indicate that the oscillation evolution of the TPTP result from quantum diffraction of the wave function, which can be explained by analogy with Fresnel diffraction from a wide slit in the spatial domain. Moreover, the ratio between the real and imaginary parts of the excited state wave function and, hence, the atomic polarization, can be controlled by the initial phase of the excitation pulse. In some special initial phase of the excitation pulse, the wave functions with purely real or imaginary parts can be obtained by measuring the population probability. This work provides a novel perspective for understanding the physical details of the interactions between atoms and chirped light pulses in the multiphoton process.

Noncontact sphygmomanometer based on pulse-wave transit time between the face and hand

NASA Astrophysics Data System (ADS)

Nakano, Kazuya; Ohnishi, Takashi; Nishidate, Izumi; Haneishi, Hideaki

2018-02-01

Systolic blood pressure (SBP) is highly sensitive to various factors such as psychological stress, and hence its continuous monitoring is essential to evaluate different health conditions. However, conventional sphygmomanometers cannot continuously measure SBP given the time-consuming setup based on a pressure cuff. Moreover, continuous biological signal monitoring is more comfortable when no sensors are attached. A solution for continuous SBP estimation is based on pulse transit time (PTT), which determines the time difference between two pulse waves at different body parts. In previous studies, we successfully measured the PTT using a contactless setup composed by two digital color cameras recording the face and hand of subjects. Then, the acquired images were transformed into blood volume by combining multiple regression analysis and a Monte Carlo method. As a result, the delay among images allowed to determine the PPT from pulse waves. In this study, we simultaneously measured SBP and PTT by using a sphygmomanometer and the two cameras, respectively. We evaluated SBP increases (i.e., stressful situations) and the corresponding PPT by asking participants to either grasp a handgrip or momentarily interrupting breath. We also determined the SBP and PTT without asking for such exercises. Comparison results show that the mean PTT under stress was significantly lower than that without stress, which is consistent with an increased SBP. Finally, we related the SBP and PTT by a nonlinear formula with a coefficient of determination of 0.59, thus confirming the effectiveness of the proposed system.

Waves in microstructured solids and negative group velocity

NASA Astrophysics Data System (ADS)

Peets, T.; Kartofelev, D.; Tamm, K.; Engelbrecht, J.

2013-07-01

Waves with negative group velocity (NGV) were discovered in optics by Sommerfeld and Brillouin, and experimentally verified in many cases, for example in left-handed media. For waves in solids, such an effect is described mostly in layered media. In this paper, it is demonstrated that in microstructured solids, waves with NGV may also exist leading to backwards pulse propagation. Two physical cases are analysed: a Mindlin-type hierarchical (a scale within a scale) material and a felt-type (made of fibres) material. For both cases, the dispersion analysis of one-dimensional waves shows that there exists certain ranges of physical parameters which lead to NGV. The results can be used in dispersion engineering for designing materials with certain properties.

Relaxation of water infiltration pulses observed with GPR

NASA Astrophysics Data System (ADS)

Hantschel, Lisa; Hemmer, Benedikt; Roth, Kurt

2017-04-01

We observe the relaxation of infiltration pulses in sandy soil with ground-penetrating radar (GPR). The spatial distribution of water in the infiltration area and its temporal evolution is represented by ordinary reflections at layer boundaries as well as multiple reflections at the wetting front and the pulse boundaries. The structure of these highly resolved signals are reproduced by numerical simulations of electromagnetic wave propagation. The temporally highly resolved electrical fields reveal the origin also of complex reflection signals. The usage of these more complex signals might allow a more detailed representation of the infiltration process by direct analysis as well as in combination with inversion techniques.

EFFECTS OF LASER RADIATION ON MATTER. LASER PLASMA: Characteristics of the evolution of a plasma formed by cw and pulse-periodic CO2 laser radiation in various gases

NASA Astrophysics Data System (ADS)

Kanevskiĭ, M. F.; Stepanova, M. A.

1990-06-01

An investigation was made of the interaction between high-power cw and pulse-periodic CO2 laser radiation and a low-threshold optical breakdown plasma near a metal surface. Characteristics of the breakdown plasma were studied as a function of the experimental conditions. A qualitative analysis was made of the results using a simple one-dimensional model for laser combustion waves.

Energy scaling of terahertz-wave parametric sources.

PubMed

Tang, Guanqi; Cong, Zhenhua; Qin, Zengguang; Zhang, Xingyu; Wang, Weitao; Wu, Dong; Li, Ning; Fu, Qiang; Lu, Qingming; Zhang, Shaojun

2015-02-23

Terahertz-wave parametric oscillators (TPOs) have advantages of room temperature operation, wide tunable range, narrow line-width, good coherence. They have also disadvantage of small pulse energy. In this paper, several factors preventing TPOs from generating high-energy THz pulses and the corresponding solutions are analyzed. A scheme to generate high-energy THz pulses by using the combination of a TPO and a Stokes-pulse-injected terahertz-wave parametric generator (spi-TPG) is proposed and demonstrated. A TPO is used as a source to generate a seed pulse for the surface-emitted spi-TPG. The time delay between the pump and Stokes pulses is adjusted to guarantee they have good temporal overlap. The pump pulses have a large pulse energy and a large beam size. The Stokes beam is enlarged to make its size be larger than the pump beam size to have a large effective interaction volume. The experimental results show that the generated THz pulse energy from the spi-TPG is 1.8 times as large as that obtained from the TPO for the same pumping pulse energy density of 0.90 J/cm(2) and the same pumping beam size of 3.0 mm. When the pumping beam sizes are 5.0 and 7.0 mm, the enhancement times are 3.7 and 7.5, respectively. The spi-TPG here is similar to a difference frequency generator; it can also be used as a Stokes pulse amplifier.

Characteristics of light reflected from a dense ionization wave with a tunable velocity.

PubMed

Zhidkov, A; Esirkepov, T; Fujii, T; Nemoto, K; Koga, J; Bulanov, S V

2009-11-20

An optically dense ionization wave (IW) produced by two femtosecond (approximately 10/30 fs) laser pulses focused cylindrically and crossing each other may become an efficient coherent x-ray converter in accordance with the Semenova-Lampe theory. The resulting velocity of a quasiplane IW in the vicinity of pulse intersection changes with the angle between the pulses from the group velocity of ionizing pulses to infinity allowing a tuning of the wavelength of x rays and their bunching. The x-ray spectra after scattering of a lower frequency and long coherent light pulse change from the monochromatic to high order harmoniclike with the duration of the ionizing pulses.

[Association between urinary microalbumin-to-creatinine ratio and brachial-ankle pulse wave velocity in hypertensive patients].

PubMed

Zhu, Hang; Xue, Hao; Wang, Guangyi; Fu, Zhenhong; Liu, Jie; Shi, Yajun

2015-04-01

To explore the association between urinary microalbumin-to-creatinine ratio (ACR) and brachial-ankle pulse wave velocity (baPWV) in hypertensive patients. A total of 877 primary hypertension patients were enrolled in this trial from September 2009 to December 2012, and were randomly recruited and patients were divided into normal ACR group (ACR < 30 mg/g, n = 723), micro-albuminuria group (30 mg/g ≤ ACR < 300 mg/g, n = 136) and macro-albuminuria group (ACR ≥ 300 mg/g, n = 18). baPWV was measure by automatic pulse wave velocity measuring system. The baPWV values in patients of micro-albuminuria group and macro-albuminuria group were significantly higher than in the normal ACR group (all P < 0.05). The baPWV value of macro-albuminuria group was significantly higher than in the micro-albuminuria group (P < 0.05). Linear correlation analysis revealed that ACR was positively correlated with baPWV (r = 0.413, P < 0.01). Multiple linear regression analysis showed that ACR independently correlated with baPWV in patients with primary hypertension (β = 0.29, R(2) = 0.112, P < 0.01) after adjusting for age, sex, body mass index, systolic blood pressure, diastolic blood pressure, blood glucose, total cholesterol, low density lipoprotein, high density lipoprotein and triglyceride. Using ACR < 30 mg/g and ACR ≥ 30 mg/g as dichotomous variable, binary logistic regression analysis showed that ACR ≥ 30 mg/g was also a risk factor of the ascending baPWV in primary hypertension patients (OR: 1.73, 95% CI: 1.62-2.98) after adjusting the traditional cardiovascular risk factors. ACR is positively correlated to baPWV in primary hypertension patients, and the ascending baPWV is a risk factor of early renal dysfunction in primary hypertension patients.

Shock wave acceleration of protons in inhomogeneous plasma interacting with ultrashort intense laser pulses

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lecz, Zs.; Andreev, A.; Max-Born Institute, Berlin

The acceleration of protons, triggered by solitary waves in expanded solid targets is investigated using particle-in-cell simulations. The near-critical density plasma is irradiated by ultrashort high power laser pulses, which generate the solitary wave. The transformation of this soliton into a shock wave during propagation in plasma with exponentially decreasing density profile is described analytically, which allows to obtain a scaling law for the proton energy. The high quality proton bunch with small energy spread is produced by reflection from the shock-front. According to the 2D simulations, the mechanism is stable only if the laser pulse duration is shorter thanmore » the characteristic development time of the parasitic Weibel instability.« less

Radiative effects of ozone waves on the Northern Hemisphere polar vortex and its modulation by the QBO

NASA Astrophysics Data System (ADS)

Silverman, Vered; Harnik, Nili; Matthes, Katja; Lubis, Sandro W.; Wahl, Sebastian

2018-05-01

The radiative effects induced by the zonally asymmetric part of the ozone field have been shown to significantly change the temperature of the NH winter polar cap, and correspondingly the strength of the polar vortex. In this paper, we aim to understand the physical processes behind these effects using the National Center for Atmospheric Research (NCAR)'s Whole Atmosphere Community Climate Model, run with 1960s ozone-depleting substances and greenhouse gases. We find a mid-winter polar vortex influence only when considering the quasi-biennial oscillation (QBO) phases separately, since ozone waves affect the vortex in an opposite manner. Specifically, the emergence of a midlatitude QBO signal is delayed by 1-2 months when radiative ozone-wave effects are removed. The influence of ozone waves on the winter polar vortex, via their modulation of shortwave heating, is not obvious, given that shortwave heating is largest during fall, when planetary stratospheric waves are weakest. Using a novel diagnostic of wave 1 temperature amplitude tendencies and a synoptic analysis of upward planetary wave pulses, we are able to show the chain of events that lead from a direct radiative effect on weak early fall upward-propagating planetary waves to a winter polar vortex modulation. We show that an important stage of this amplification is the modulation of individual wave life cycles, which accumulate during fall and early winter, before being amplified by wave-mean flow feedbacks. We find that the evolution of these early winter upward planetary wave pulses and their induced stratospheric zonal mean flow deceleration is qualitatively different between QBO phases, providing a new mechanistic view of the extratropical QBO signal. We further show how these differences result in opposite radiative ozone-wave effects between east and west QBOs.

A narrow-band injection-seeded pulsed titanium:sapphire oscillator-amplifier system with on-line chirp analysis for high-resolution spectroscopy.

PubMed

Hannemann, S; van Duijn, E-J; Ubachs, W

2007-10-01

A narrow-band tunable injection-seeded pulsed titanium:sapphire laser system has been developed for application in high-resolution spectroscopic studies at the fundamental wavelengths in the near infrared as well as in the ultraviolet, deep ultraviolet, and extreme ultraviolet after upconversion. Special focus is on the quantitative assessment of the frequency characteristics of the oscillator-amplifier system on a pulse-to-pulse basis. Frequency offsets between continuous-wave seed light and the pulsed output are measured as well as linear chirps attributed mainly to mode pulling effects in the oscillator cavity. Operational conditions of the laser are found in which these offset and chirp effects are minimal. Absolute frequency calibration at the megahertz level of accuracy is demonstrated on various atomic and molecular resonance lines.

Square wave voltammetry at the dropping mercury electrode: Experimental

USGS Publications Warehouse

Turner, J.A.; Christie, J.H.; Vukovic, M.; Osteryoung, R.A.

1977-01-01

Experimental verification of earlier theoretical work for square wave voltammetry at the dropping mercury electrode is given. Experiments using ferric oxalate and cadmium(II) in HCl confirm excellent agreement with theory. Experimental peak heights and peak widths are found to be within 2% of calculated results. An example of trace analysis using square wave voltammetry at the DME is presented. The technique is shown to have the same order of sensitivity as differential pulse polarography but is much faster to perform. A detection limit for cadmium in 0.1 M HCl for the system used here was 7 ?? 10-8 M.

The analysis and compensation of errors of precise simple harmonic motion control under high speed and large load conditions based on servo electric cylinder

NASA Astrophysics Data System (ADS)

Ma, Chen-xi; Ding, Guo-qing

2017-10-01

Simple harmonic waves and synthesized simple harmonic waves are widely used in the test of instruments. However, because of the errors caused by clearance of gear and time-delay error of FPGA, it is difficult to control servo electric cylinder in precise simple harmonic motion under high speed, high frequency and large load conditions. To solve the problem, a method of error compensation is proposed in this paper. In the method, a displacement sensor is fitted on the piston rod of the electric cylinder. By using the displacement sensor, the real-time displacement of the piston rod is obtained and fed back to the input of servo motor, then a closed loop control is realized. There is compensation of pulses in the next period of the synthetic waves. This paper uses FPGA as the processing core. The software mainly comprises a waveform generator, an Ethernet module, a memory module, a pulse generator, a pulse selector, a protection module, an error compensation module. A durability of shock absorbers is used as the testing platform. The durability mainly comprises a single electric cylinder, a servo motor for driving the electric cylinder, and the servo motor driver.

Venus Lightning: What We Have Learned from the Venus Express Fluxgate Magnetometer

NASA Astrophysics Data System (ADS)

Russell, C. T.; Strangeway, R. J.; Wei, H. Y.; Zhang, T. L.

2010-03-01

The Venus Express magnetometer sees short (tens of milliseconds) pulses of EM waves in the Venus ionosphere as predicted by the lightning model for the PVO electric pulses. These waves are stronger than similar terrestrial signals produced by lightning.

Effect of Pulsing in Low-Level Light Therapy

PubMed Central

Hashmi, Javad T.; Huang, Ying-Ying; Sharma, Sulbha K.; Kurup, Divya Balachandran; De Taboada, Luis; Carroll, James D.; Hamblin, Michael R.

2010-01-01

Background and Objective Low level light (or laser) therapy (LLLT) is a rapidly growing modality used in physical therapy, chiropractic, sports medicine and increasingly in mainstream medicine. LLLT is used to increase wound healing and tissue regeneration, to relieve pain and inflammation, to prevent tissue death, to mitigate degeneration in many neurological indications. While some agreement has emerged on the best wavelengths of light and a range of acceptable dosages to be used (irradiance and fluence), there is no agreement on whether continuous wave or pulsed light is best and on what factors govern the pulse parameters to be chosen. Study Design/Materials and Methods The published peer-reviewed literature was reviewed between 1970 and 2010. Results The basic molecular and cellular mechanisms of LLLT are discussed. The type of pulsed light sources available and the parameters that govern their pulse structure are outlined. Studies that have compared continuous wave and pulsed light in both animals and patients are reviewed. Frequencies used in other pulsed modalities used in physical therapy and biomedicine are compared to those used in LLLT. Conclusion There is some evidence that pulsed light does have effects that are different from those of continuous wave light. However further work is needed to define these effects for different disease conditions and pulse structures. PMID:20662021

Effect of pulsing in low-level light therapy.

PubMed

Hashmi, Javad T; Huang, Ying-Ying; Sharma, Sulbha K; Kurup, Divya Balachandran; De Taboada, Luis; Carroll, James D; Hamblin, Michael R

2010-08-01

Low level light (or laser) therapy (LLLT) is a rapidly growing modality used in physical therapy, chiropractic, sports medicine and increasingly in mainstream medicine. LLLT is used to increase wound healing and tissue regeneration, to relieve pain and inflammation, to prevent tissue death, to mitigate degeneration in many neurological indications. While some agreement has emerged on the best wavelengths of light and a range of acceptable dosages to be used (irradiance and fluence), there is no agreement on whether continuous wave or pulsed light is best and on what factors govern the pulse parameters to be chosen. The published peer-reviewed literature was reviewed between 1970 and 2010. The basic molecular and cellular mechanisms of LLLT are discussed. The type of pulsed light sources available and the parameters that govern their pulse structure are outlined. Studies that have compared continuous wave and pulsed light in both animals and patients are reviewed. Frequencies used in other pulsed modalities used in physical therapy and biomedicine are compared to those used in LLLT. There is some evidence that pulsed light does have effects that are different from those of continuous wave light. However further work is needed to define these effects for different disease conditions and pulse structures. (c) 2010 Wiley-Liss, Inc.

Terahertz wave electro-optic measurements with optical spectral filtering

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ilyakov, I. E., E-mail: igor-ilyakov@mail.ru; Shishkin, B. V.; Kitaeva, G. Kh.

We propose electro-optic detection techniques based on variations of the laser pulse spectrum induced during pulse co-propagation with terahertz wave radiation in a nonlinear crystal. Quantitative comparison with two other detection methods is made. Substantial improvement of the sensitivity compared to the standard electro-optic detection technique (at high frequencies) and to the previously shown technique based on laser pulse energy changes is demonstrated in experiment.

Prediction of all-cause death in hemodialysis patients using elevated postdialysis pulse wave velocity.

PubMed

Fu, Xiaohong; Yang, Jihong; Fan, Zhaoxin; Chen, Xianguang; Wu, Jie; Li, Jie; Wu, Hua

2016-02-01

To identify the relationship between predialysis pulse wave velocity (PWV), postdialysis PWV during 1 hemodialysis (HD) session, and deaths in maintenance HD patients. 43 patients were recruited. PWV was measured before and after one HD session and dialysis- related data were recorded. Clinical data such as blood pressure, blood lipids, and blood glucose, were carefully observed and managed in a 5-year follow-up. The association between all-cause death, predialysis PWV, postdialysis PWV, change of PWV (ΔPWV), and other related variables were analyzed. After 5 years, 17 patients (39.5%) died. Univariate Cox regression analysis showed that all-cause death of the patients significantly correlated with age, postdialysis PWV, and ΔPWV. Multivariate Cox regression analysis revealed that postdialysis PWV was an independent predictor for all-cause death in these patients (HR: 1.377, 95% CI: 1.146 - 1.656, p = 0.001). Elevated postdialysis PWV significantly correlated with and was an independent predictor for all-cause death in maintenance HD patients.

Observation of sum-frequency-generation-induced cascaded four-wave mixing using two crossing femtosecond laser pulses in a 0.1 mm beta-barium-borate crystal.

PubMed

Liu, Weimin; Zhu, Liangdong; Fang, Chong

2012-09-15

We demonstrate the simultaneous generation of multicolor femtosecond laser pulses spanning the wavelength range from UV to near IR in a 0.1 mm Type I beta-barium borate crystal from 800 nm fundamental and weak IR super-continuum white light (SCWL) pulses. The multicolor broadband laser pulses observed are attributed to two concomitant cascaded four-wave mixing (CFWM) processes as corroborated by calculation: (1) directly from the two incident laser pulses; (2) by the sum-frequency generation (SFG) induced CFWM process (SFGFWM). The latter signal arises from the interaction between the frequency-doubled fundamental pulse (400 nm) and the SFG pulse generated in between the fundamental and IR-SCWL pulses. The versatility and simplicity of this spatially dispersed multicolor self-compressed laser pulse generation offer compact and attractive methods to conduct femtosecond stimulated Raman spectroscopy and time-resolved multicolor spectroscopy.

On the Theory of High-Power Ultrashort Pulse Propagation in Raman-Active Media

NASA Technical Reports Server (NTRS)

Belenov, E. M.; Isakov, V. A.; Kanavin, A. P.; Smetanin, I. V.

1996-01-01

The propagation of an intense femtosecond pulse in a Raman-active medium is analyzed. An analytic solution which describes in explicit form the evolution of the light pulse is derived. The field of an intense light wave undergoes a substantial transformation as the wave propagates through the medium. The nature of this transformation can change over time scales comparable to the period of the optical oscillations. As a result, the pulse of sufficiently high energy divides into stretched and compressed domains where the field decreases and increases respectively.

RARE/Turbo Spin Echo Imaging with Simultaneous MultiSlice Wave-CAIPI

PubMed Central

Eichner, Cornelius; Bhat, Himanshu; Grant, P. Ellen; Wald, Lawrence L.; Setsompop, Kawin

2014-01-01

Purpose To enable highly accelerated RARE/Turbo Spin Echo (TSE) imaging using Simultaneous MultiSlice (SMS) Wave-CAIPI acquisition with reduced g-factor penalty. Methods SMS Wave-CAIPI incurs slice shifts across simultaneously excited slices while playing sinusoidal gradient waveforms during the readout of each encoding line. This results in an efficient k-space coverage that spreads aliasing in all three dimensions to fully harness the encoding power of coil sensitivities. The novel MultiPINS radiofrequency (RF) pulses dramatically reduce the power deposition of multiband (MB) refocusing pulse, thus allowing high MB factors within the Specific Absorption Rate (SAR) limit. Results Wave-CAIPI acquisition with MultiPINS permits whole brain coverage with 1 mm isotropic resolution in 70 seconds at effective MB factor 13, with maximum and average g-factor penalties of gmax=1.34 and gavg=1.12, and without √R penalty. With blipped-CAIPI, the g-factor performance was degraded to gmax=3.24 and gavg=1.42; a 2.4-fold increase in gmax relative to Wave-CAIPI. At this MB factor, the SAR of the MultiBand and PINS pulses are 4.2 and 1.9 times that of the MultiPINS pulse, while the peak RF power are 19.4 and 3.9 times higher. Conclusion Combination of the two technologies, Wave-CAIPI and MultiPINS pulse, enables highly accelerated RARE/TSE imaging with low SNR penalty at reduced SAR. PMID:25640187

Mode-locked laser with pulse interleavers in a monolithic photonic integrated circuit for millimeter wave and terahertz carrier generation.

PubMed

Lo, Mu-Chieh; Guzmán, Robinson; Gordón, Carlos; Carpintero, Guillermo

2017-04-15

This Letter presents a photonics-based millimeter wave and terahertz frequency synthesizer using a monolithic InP photonic integrated circuit composed of a mode-locked laser (MLL) and two pulse interleaver stages to multiply the repetition rate frequency. The MLL is a multiple colliding pulse MLL producing an 80 GHz repetition rate pulse train. Through two consecutive monolithic pulse interleaver structures, each doubling the repetition rate, we demonstrate the achievement of 160 and 320 GHz. The fabrication was done on a multi-project wafer run of a generic InP photonic technology platform.

Non-Gaussian statistics and optical rogue waves in stimulated Raman scattering.

PubMed

Monfared, Yashar E; Ponomarenko, Sergey A

2017-03-20

We explore theoretically and numerically optical rogue wave formation in stimulated Raman scattering inside a hydrogen filled hollow core photonic crystal fiber. We assume a weak noisy Stokes pulse input and explicitly construct the input Stokes pulse ensemble using the coherent mode representation of optical coherence theory, thereby providing a link between optical coherence and rogue wave theories. We show that the Stokes pulse peak power probability distribution function (PDF) acquires a long tail in the limit of nearly incoherent input Stokes pulses. We demonstrate a clear link between the PDF tail magnitude and the source coherence time. Thus, the latter can serve as a convenient parameter to control the former. We explain our findings qualitatively using the concepts of statistical granularity and global degree of coherence.

Pulse Phase Dynamic Thermal Tomography Investigation on the Defects of the Solid-Propellant Missile Engine Cladding Layer

NASA Astrophysics Data System (ADS)

Peng, Wei; Wang, Fei; Liu, Jun-yan; Xiao, Peng; Wang, Yang; Dai, Jing-min

2018-04-01

Pulse phase dynamic thermal tomography (PP-DTT) was introduced as a nondestructive inspection technique to detect the defects of the solid-propellant missile engine cladding layer. One-dimensional thermal wave mathematical model stimulated by pulse signal was developed and employed to investigate the thermal wave transmission characteristics. The pulse phase algorithm was used to extract the thermal wave characteristic of thermal radiation. Depth calibration curve was obtained by fuzzy c-means algorithm. Moreover, PP-DTT, a depth-resolved photothermal imaging modality, was employed to enable three-dimensional (3D) visualization of cladding layer defects. The comparison experiment between PP-DTT and classical dynamic thermal tomography was investigated. The results showed that PP-DTT can reconstruct the 3D topography of defects in a high quality.

Discharge conditions for CW and pulse-modulated surface-wave plasmas in low-temperature sterilization

NASA Astrophysics Data System (ADS)

Xu, L.; Terashita, F.; Nonaka, H.; Ogino, A.; Nagata, T.; Koide, Y.; Nanko, S.; Kurawaki, I.; Nagatsu, M.

2006-01-01

The discharge conditions required for low-temperature plasma sterilization were investigated using low-pressure surface-wave plasma (SWP). The discharge conditions for both continuous wave (CW) and pulse-modulated SWPs in low-temperature sterilization of Geobacillus stearothermophilus with a population of 1.5 × 106 and 3.0 × 106 were studied by varying the microwave input power from 500 W to 3 kW, and the effective plasma treatment time from 40 to 300 s. Results showed that sterilization was possible in a shorter treatment time using a higher microwave power for both CW and pulse-modulated SWPs. Pulse-modulated SWPs gave effective sterilization at a temperature roughly 10 to 20 °C below that of CW SWPs under the same average microwave power.

Full-field wrist pulse signal acquisition and analysis by 3D Digital Image Correlation

NASA Astrophysics Data System (ADS)

Xue, Yuan; Su, Yong; Zhang, Chi; Xu, Xiaohai; Gao, Zeren; Wu, Shangquan; Zhang, Qingchuan; Wu, Xiaoping

2017-11-01

Pulse diagnosis is an essential part in four basic diagnostic methods (inspection, listening, inquiring and palpation) in traditional Chinese medicine, which depends on longtime training and rich experience, so computerized pulse acquisition has been proposed and studied to ensure the objectivity. To imitate the process that doctors using three fingertips with different pressures to feel fluctuations in certain areas containing three acupoints, we established a five dimensional pulse signal acquisition system adopting a non-contacting optical metrology method, 3D digital image correlation, to record the full-field displacements of skin fluctuations under different pressures. The system realizes real-time full-field vibration mode observation with 10 FPS. The maximum sample frequency is 472 Hz for detailed post-processing. After acquisition, the signals are analyzed according to the amplitude, pressure, and pulse wave velocity. The proposed system provides a novel optical approach for digitalizing pulse diagnosis and massive pulse signal data acquisition for various types of patients.

Generalization of helicoidal beams for short pulses.

PubMed

Thomas, Jean-Louis; Brunet, Thomas; Coulouvrat, François

2010-01-01

A generalization to the transient regime is developed for waves with a phase singularity of the screw type. These singular waves are commonly called vortices for all kind of waves as, for instance, optical vortex or acoustical vortex. We generalize the definition of vortices to get an azimuthal velocity invariant for all the frequency components contained in the broad spectrum of a short pulse. This generalization leads to a modification of the orbital angular momentum definition. Another generalization is introduced by considering helicoidal waves with a finite number of turns. We demonstrate that, in this last case, the topological charge is no longer an integer. This provides a physical interpretation to vortices of fractional charge that are involved here to take into account the diffraction occurring at both tips of the now finite helical wave front. We show that shortening the pulse implies an angular localization of the wave energy and, as a consequence, a spreading of the angular momentum amplitude due to the uncertainty principle.

Imaging feedback for histotripsy by characterizing dynamics of acoustic radiation force impulse (ARFI)-induced shear waves excited in a treated volume.

PubMed

Wang, Tzu-Yin; Hall, Timothy L; Xu, Zhen; Fowlkes, J Brian; Cain, Charles A

2014-07-01

Our previous study indicated that shear waves decay and propagate at a lower speed as they propagate into a tissue volume mechanically fractionated by histotripsy. In this paper, we hypothesize that the change in the shear dynamics is related to the degree of tissue fractionation, and can be used to predict histotripsy treatment outcomes. To test this hypothesis, lesions with different degrees of tissue fractionation were created in agar-graphite tissue phantoms and ex vivo kidneys with increasing numbers of therapy pulses, from 0 to 2000 pulses per treatment location. The therapy pulses were 3-cycle 750-kHz focused ultrasound delivered at a peak negative/positive pressure of 17/108 MPa and a repetition rate of 50 Hz. The shear waves were excited by acoustic radiation force impulse (ARFI) focused at the center of the lesion. The spatial and temporal behavior of the propagating shear waves was measured with ultrasound plane wave imaging. The temporal displacement profile at a lateral location 10 mm offset to the shear excitation region was detected with M-mode imaging. The decay and delay of the shear waves were quantitatively characterized on the temporal displacement profile. Results showed significant changes in two characteristics on the temporal displacement profile: the peak-to-peak displacement decayed exponentially with increasing numbers of therapy pulses; the relative time-to-peak displacement increased with increasing numbers of therapy pulses, and appeared to saturate at higher numbers of pulses. Correspondingly, the degree of tissues fractionation, as indicated by the percentage of structurally intact cell nuclei, decreased exponentially with increasing numbers of therapy pulses. Strong linear correlations were found between the two characteristics and the degree of tissue fractionation. These results suggest that the characteristics of the shear temporal displacement profile may provide useful feedback information regarding the treatment outcomes.

Self-compression of spatially limited laser pulses in a system of coupled light-guides

NASA Astrophysics Data System (ADS)

Balakin, A. A.; Litvak, A. G.; Mironov, V. A.; Skobelev, S. A.

2018-04-01

The self-action features of wave packets propagating in a 2D system of equidistantly arranged fibers are studied analytically and numerically on the basis of the discrete nonlinear Schrödinger equation. Self-consistent equations for the characteristic scales of a Gaussian wave packet are derived on the basis of the variational approach, which are proved numerically for powers P < 10 P_cr , slightly exceeding the critical one for self-focusing. At higher powers, the wave beams become filamented, and their amplitude is limited due to the nonlinear breaking of the interaction between neighboring light-guides. This makes it impossible to collect a powerful wave beam in a single light-guide. Variational analysis shows the possibility of the adiabatic self-compression of soliton-like laser pulses in the process of 3D self-focusing on the central light-guide. However, further increase of the field amplitude during self-compression leads to the development of longitudinal modulation instability and the formation of a set of light bullets in the central fiber. In the regime of hollow wave beams, filamentation instability becomes predominant. As a result, it becomes possible to form a set of light bullets in optical fibers located on the ring.

Pulsed-wave Doppler ultrasonographic evaluation of hepatic vein in dogs with tricuspid regurgitation

PubMed Central

Kim, Jaehwan; Kim, Soyoung

2017-01-01

This study was performed to identify the relationships between hepatic vein (HV) measurements, including flow velocity and waveform, using pulsed-wave (PW) Doppler ultrasonography, and the severity of tricuspid regurgitation (TR) in dogs. The study included 22 dogs with TR and 7 healthy dogs. The TR group was subdivided into 3 groups according to TR jet profile obtained by echocardiography. The hepatic venous waveform was obtained and classified into 3 types. A variety of HV measurements, including the maximal velocities of the atrial systolic, systolic (S), end ventricular systolic, and diastolic (D) waves and the ratio of the S- and D- wave velocities (S/D ratio), were acquired. TR severity was significantly correlated with the S- (r = −0.380, p = 0.042) and D- (r = 0.468, p = 0.011) wave velocities and the S/D ratio (r = −0.747, p < 0.001). Receiver operating characteristic curve analysis revealed the highest sensitivity and specificity for the S/D ratio (89% and 75%, respectively) at a threshold of 0.97 with excellent accuracy (AUC = 0.911, p < 0.001). In conclusion, PW Doppler ultrasonography of the HV can be used to identify the presence of significant TR and to classify TR severity in dogs. PMID:27515264

Pulsed-wave Doppler ultrasonographic evaluation of hepatic vein in dogs with tricuspid regurgitation.

PubMed

Kim, Jaehwan; Kim, Soyoung; Eom, Kidong

2017-03-30

This study was performed to identify the relationships between hepatic vein (HV) measurements, including flow velocity and waveform, using pulsed-wave (PW) Doppler ultrasonography, and the severity of tricuspid regurgitation (TR) in dogs. The study included 22 dogs with TR and 7 healthy dogs. The TR group was subdivided into 3 groups according to TR jet profile obtained by echocardiography. The hepatic venous waveform was obtained and classified into 3 types. A variety of HV measurements, including the maximal velocities of the atrial systolic, systolic (S), end ventricular systolic, and diastolic (D) waves and the ratio of the S- and D- wave velocities (S/D ratio), were acquired. TR severity was significantly correlated with the S- ( r = -0.380, p = 0.042) and D- ( r = 0.468, p = 0.011) wave velocities and the S/D ratio ( r = -0.747, p ＜ 0.001). Receiver operating characteristic curve analysis revealed the highest sensitivity and specificity for the S/D ratio (89% and 75%, respectively) at a threshold of 0.97 with excellent accuracy (AUC = 0.911, p ＜ 0.001). In conclusion, PW Doppler ultrasonography of the HV can be used to identify the presence of significant TR and to classify TR severity in dogs.

Reduction and coding of synthetic aperture radar data with Fourier transforms

NASA Technical Reports Server (NTRS)

Tilley, David G.

1995-01-01

Recently, aboard the Space Radar Laboratory (SRL), the two roles of Fourier Transforms for ocean image synthesis and surface wave analysis have been implemented with a dedicated radar processor to significantly reduce Synthetic Aperture Radar (SAR) ocean data before transmission to the ground. The object was to archive the SAR image spectrum, rather than the SAR image itself, to reduce data volume and capture the essential descriptors of the surface wave field. SAR signal data are usually sampled and coded in the time domain for transmission to the ground where Fourier Transforms are applied both to individual radar pulses and to long sequences of radar pulses to form two-dimensional images. High resolution images of the ocean often contain no striking features and subtle image modulations by wind generated surface waves are only apparent when large ocean regions are studied, with Fourier transforms, to reveal periodic patterns created by wind stress over the surface wave field. Major ocean currents and atmospheric instability in coastal environments are apparent as large scale modulations of SAR imagery. This paper explores the possibility of computing complex Fourier spectrum codes representing SAR images, transmitting the coded spectra to Earth for data archives and creating scenes of surface wave signatures and air-sea interactions via inverse Fourier transformations with ground station processors.

Logic circuit detects both present and missing negative pulses in superimposed wave trains

NASA Technical Reports Server (NTRS)

Rice, R. E.

1967-01-01

Pulse divide and determination network provides a logical determination of pulse presence within a data train. The network uses digital logic circuitry to divide positive and negative pulses, to shape the separated pulses, and to determine, by means of coincidence logic, if negative pulses are missing from the pulse train.

Conversion of ultrashort laser pulses to wavelengths above 3 mm in tapered germanate fibres

NASA Astrophysics Data System (ADS)

Anashkina, E. A.; Andrianov, A. V.; Kim, A. V.

2015-05-01

Tapered germanate fibres are proposed for effective adiabatic conversion of Raman soliton pulses to the mid-IR region. A theoretical analysis demonstrates that, in fibres with anomalous group velocity dispersion decreasing along their length, wavelengths of up to 3.5 μm can be reached, which are unattainable in fibres with a constant core diameter at the same parameters of a 2-μm input signal. The analysis relies on a one-way wave equation that takes into account the combined effect of dispersion, Kerr and Raman nonlinearities, nonlinear dispersion and optical losses and the frequency dependence of the effective fundamental transverse mode size.

Childhood Obesity Associates Haemodynamic and Vascular Changes That Result in Increased Central Aortic Pressure with Augmented Incident and Reflected Wave Components, without Changes in Peripheral Amplification

PubMed Central

Castro, Juan M.; García-Espinosa, Victoria; Curcio, Santiago; Arana, Maite; Chiesa, Pedro; Giachetto, Gustavo; Zócalo, Yanina; Bia, Daniel

2016-01-01

The aims were to determine if childhood obesity is associated with increased central aortic blood pressure (BP) and to characterize haemodynamic and vascular changes associated with BP changes in obese children and adolescents by means of analyzing changes in cardiac output (stroke volume, SV), arterial stiffness (aortic pulse wave velocity, PWV), peripheral vascular resistances (PVR), and net and relative contributions of reflected waves to the aortic pulse wave amplitude. We included 117 subjects (mean/range age: 10 (5–15) years, 49 females), who were obese (OB) or had normal weight (NW). Peripheral and central aortic BP, PWV, and pulse wave-derived parameters (augmentation index, amplitude of forward and backward components) were measured with tonometry (SphygmoCor) and oscillometry (Mobil-O-Graph). With independence of the presence of dyslipidemia, hypertension, or sedentarism, the aortic systolic and pulse BP were higher in OB than in NW subjects. The increase in central BP could not be explained by the elevation in the relative contribution of reflections to the aortic pressure wave and higher PVR or by an augmented peripheral reflection coefficient. Instead, the rise in central BP could be explained by an increase in the amplitude of both incident and reflect wave components associated to augmented SV and/or PWV. PMID:26881081

Bipolar-pulses observed by the LRS/WFC-L onboard KAGUYA - Plausible evidence of lunar dust impact -

NASA Astrophysics Data System (ADS)

Kasahara, Yoshiya; Horie, Hiroki; Hashimoto, Kozo; Omura, Yoshiharu; Goto, Yoshitaka; Kumamoto, Atsushi; Ono, Takayuki; Tsunakawa, Hideo; Lrs/Wfc Team; Map/Lmag Team

2010-05-01

Introduction: The waveform capture (WFC) [1] is one of the subsystems of the Lunar Radar Sounder (LRS) [2] on board the KAGUYA spacecraft. By taking advantage of a moon orbiter, the WFC measures plasma waves and radio emis-sions around the moon. The WFC measures two components of electric wave signals detected by the two orthogonal 30 m tip-to-tip antennas from 100Hz to 1MHz. The WFC consists of the WFC-L which meas-ures electric waveform from 100Hz to 100kHz, and the WFC-H which is a fast sweep frequency analyz-er covering from 1kHz up to 1MHz. The WFC-L has two operation modes: DIFF and MONO. In DIFF mode, signals from two pairs of 30m tip-to-tip dipole antennas are obtained. MONO mode is namely an interferometry mode and we separately measure the signals from a pair of monopole antennas. This mode is dedicated to measure the phase velocities and wave numbers of plasma waves. Bipolar-pulses with their time scales of a few ms upto several tens ms were often observed by the WFC-L. Some of them are classified into elec-trostatic solitary waves (ESW) [3], while another type of bipolar pulses which are supposed to be caused by lunar dust impacts are also observed. In the present paper, we introduce the latter type of bipolar-pulses. Observation: In general, ESWs are caused by electron-holes in the nonlinear evolution of electron beam instability. Therefore waveform of ESW is basically symmetric and its propagation direction is parallel to the am-bient magnetic field. On the other hand, another type of bipolar pulses are characterized by their asymmetric waveforms, that is, the latter half of pulse is longer than the first half. It is also noted that detection probability of such asymmetric bipolar pulses in MONO mode is much higher than that in DIFF mode. This is because bipolar pulses detected by a pair of monopole antennas in MONO mode are almost identical (pulses are simultaneously detected with both monopole anten-nas and the polarities of these pulses are also same) and thus most of bipolar-pulses which can be detected in MONO mode are cancelled in DIFF mode. This fact suggests that these bipolar pulses are not a kind of natural wave but these are caused by instantaneous potential changes of the KAGUYA spacecraft. Discussion: Similar type of bipolar-pulses has been observed by the monopole antenna measurements using Radio and Plasma Wave Science (RPWS) instruments on-board Cassini around Saturn [4]. They demonstrated that these bipolar pulses are caused by impacts of dusts floating around the Saturn. It is well-known that lunar dusts are widely dis-tributed in higher altitude range around the moon and it is plausible that these bipolar pulses are caused by the lunar dust impacts. In the presentation, we show the detailed charac-teristics of bipolar pulses detected by the WFC-L onboard KAGUYA. References: [1] Y. Kasahara et al., Earth, Planets and Space, 60(4), 341-351, 2008. [2] T. Ono et al., Earth, Planets and Space, 60(4), 321-332, 2008. [3] K. Hashimoto et al., The 4th SELENE (KAGUYA) Science Working Team Meeting, (this issue), 2010. [4] W.S. Kurth et al, Planetary and Space Science, 54(9-10), 988-998, 2006.

Photoacoustic simulation study of chirp excitation response from different size absorbers

NASA Astrophysics Data System (ADS)

Jnawali, K.; Chinni, B.; Dogra, V.; Rao, N.

2017-03-01

Photoacoustic (PA) imaging is a hybrid imaging modality that integrates the strength of optical and ultrasound imaging. Nanosecond (ns) pulsed lasers used in current PA imaging systems are expensive, bulky and they often waste energy. We propose and evaluate, through simulations, the use of a continuous wave (CW) laser whose amplitude is linear frequency modulated (chirp) for PA imaging. The chirp signal provides signal-to-side-lobe ratio (SSR) improvement potential and full control over PA signal frequencies excited in the sample. The PA signal spectrum is a function of absorber size and the time frequencies present in the chirp. A mismatch between the input chirp spectrum and the output PA signal spectrum can affect the compressed pulse that is recovered from cross-correlating the two. We have quantitatively characterized this effect. The k-wave Matlab tool box was used to simulate PA signals in three dimensions for absorbers ranging in size from 0.1 mm to 0.6 mm, in response to laser excitation amplitude that is linearly swept from 0.5 MHz to 4 MHz. This sweep frequency range was chosen based on the spectrum analysis of a PA signal generated from ex-vivo human prostate tissue samples. In comparison, the energy wastage by a ns laser pulse was also estimated. For the chirp methodology, the compressed pulse peak amplitude, pulse width and side lobe structure parameters were extracted for different size absorbers. While the SSR increased 6 fold with absorber size, the pulse width decreased by 25%.

Nd:YAG Pulsed Laser based flaw imaging techniques for noncontact NDE of an aluminum plate

NASA Astrophysics Data System (ADS)

Park, Woong-Ki; Lee, Changgil; Park, Seunghee

2012-04-01

Recently, the longitudinal, shear and surface waves have been very widely used as a kind of ultrasonic wave exploration methods to identify internal defects of metallic structures. The ultrasonic wave-based non-destructive testing (NDT) is one of main non-destructive inspection techniques for a health assessment about nuclear power plant, aircraft, ships, and/or automobile manufacturing. In this study, a noncontact pulsed laser-based flaw imaging NDT technique is implemented to detect the damage of a plate-like structure and to identify the location of the damage. To achieve this goal, the Nd:YAG pulsed laser equipment is used to generate a guided wave and scans a specific area to find damage location. The Nd: YAG pulsed laser is used to generate Lamb wave and piezoelectric sensors are installed to measure structural responses. Ann aluminum plate is investigated to verify the effectiveness and the robustness of the proposed NDT approach. A notch is a target to detect, which is inflicted on the surface of an aluminum plate. The damagesensitive features are extracted by comparing the time of flight of the guided wave obtained from an acoustic emission (AE) sensor and make use of the flaw imaging techniques of the aluminum plate.

Exciting Alfven Waves using Modulated Electron Heating by High Power Microwaves

NASA Astrophysics Data System (ADS)

Wang, Yuhou; Gekelman, Walter; Pribyl, Patrick; van Compernolle, Bart; Papadopoulos, Konstantinos

2014-10-01

Experiments exploring the physics of ionospheric modification with intense perpendicular propagating waves (k-> ⊥B->0) on the Large Plasma Device (LaPD) at UCLA have been upgraded with the addition of a high power rapidly pulsed microwave source. The plasma is irradiated with ten pulses (250 kW X-band) near the upper-hybrid frequency. The pulses are modulated at a frequency of a fraction (0.1-1.0) of fci (ion cyclotron frequency). Based on a previous single-pulse experiment, the modulated electron heating may drive a large amplitude shear Alfvén wave (f

Pump-dump iterative squeezing of vibrational wave packets.

PubMed

Chang, Bo Y; Sola, Ignacio R

2005-12-22

The free motion of a nonstationary vibrational wave packet in an electronic potential is a source of interesting quantum properties. In this work we propose an iterative scheme that allows continuous stretching and squeezing of a wave packet in the ground or in an excited electronic state, by switching the wave function between both potentials with pi pulses at certain times. Using a simple model of displaced harmonic oscillators and delta pulses, we derive the analytical solution and the conditions for its possible implementation and optimization in different molecules and electronic states. We show that the main constraining parameter is the pulse bandwidth. Although in principle the degree of squeezing (or stretching) is not bounded, the physical resources increase quadratically with the number of iterations, while the achieved squeezing only increases linearly.

Laser control of electronic transitions of wave packet by using quadratically chirped pulses.

PubMed

Zou, Shiyang; Kondorskiy, Alexey; Mil'nikov, Gennady; Nakamura, Hiroki

2005-02-22

An effective scheme is proposed for the laser control of wave packet dynamics. It is demonstrated that by using specially designed quadratically chirped pulses, fast and nearly complete excitation of wave packet can be achieved without significant distortion of its shape. The parameters of the laser pulse can be estimated analytically from the Zhu-Nakamura theory of nonadiabatic transition. If the wave packet is not too narrow or not too broad, then the scheme is expected to be utilizable for multidimensional systems. The scheme is applicable to various processes such as simple electronic excitation, pump-dump, and selective bond breaking, and it is actually numerically demonstrated to work well by taking diatomic and triatomic molecules (LiH, NaK, H(2)O) as examples.

Laser control of electronic transitions of wave packet by using quadratically chirped pulses

NASA Astrophysics Data System (ADS)

Zou, Shiyang; Kondorskiy, Alexey; Mil'nikov, Gennady; Nakamura, Hiroki

2005-02-01

An effective scheme is proposed for the laser control of wave packet dynamics. It is demonstrated that by using specially designed quadratically chirped pulses, fast and nearly complete excitation of wave packet can be achieved without significant distortion of its shape. The parameters of the laser pulse can be estimated analytically from the Zhu-Nakamura theory of nonadiabatic transition. If the wave packet is not too narrow or not too broad, then the scheme is expected to be utilizable for multidimensional systems. The scheme is applicable to various processes such as simple electronic excitation, pump-dump, and selective bond breaking, and it is actually numerically demonstrated to work well by taking diatomic and triatomic molecules (LiH, NaK, H2O) as examples.

2008 Wen-Chuan Mw 8.3 Earthquake: Dynamic Deformation Analysis for Seismic Surface Waveforms with 1-Hz GPS PPP Results

NASA Astrophysics Data System (ADS)

Shi, C.; Lou, Y.; Zhang, H.; Zhao, Q.; Liu, J.

2008-12-01

Some 1-Hz GPS data in China during Sichuan Wen-Chuan Mw8.3 Earthquake are processed with instantaneous Precise Point Positioning (PPP) technique using software PANDA developed in Wuhan University. Near-field GPS stations are located 30km away but lost data after 10s while several far-field sites are 300km~1200km away from epicenter. Results indicate that plane displacements exceed 40cm within 10seconds in near field while the post-seismic deformation is northwestward at the magnitude of around 30cm. Seismic surface waveforms as LOVE and Rayleigh waves can be seen clearly in the dynamic deformation process of station XANY and CHGO (in KunMing city, Yunnan Province). Love wave's first vibration is in northwestward and then southeastward, after about one cycle, Rayleigh wave comes. Love wave is at the speed of about 4km/s, Rayleigh's is about 2.85km/s. There are two deformation pulses in Rayleigh waveforms during the period of about 120 seconds monitored at station XANY, which is about 600km from epicenter. One pulse is in counter-clockwise movement and the other is clock-wise, which seems to reveal the fact that there are two kinds of rupture process in totally opposite direction. Spectral analysis shows that there are mainly two kinds of periods in the surface waves reflected by the 1-Hz horizontal deformations, one is about 5~10s (6s and 8s) and another is about 20s, corresponding to Rayleigh and Love wave respectively. Rayleigh's wavelength is about 20km, which indicates that the hypocenter is about in the depth of 10km.

Stress wave emission from plasmonic nanobubbles

NASA Astrophysics Data System (ADS)

Brujan, Emil-Alexandru

2017-01-01

Stress wave emission from the collapse of cavitation nanobubbles, generated after irradiation of single-spherical gold nanoparticles with laser pulses, was investigated numerically. The significant parameters of this study are the nanoparticle radius, laser pulse duration, and laser fluence. For conditions comparable to those existing during plasmonic photothermal therapy, a purely compressive pressure wave is emitted during nanobubble collapse, not a shock. In the initial stage of its propagation, the stress wave amplitude is proportional to the inverse of the stress wave radius. The maximum amplitude and the duration of the stress wave decreases with the laser fluence, laser pulse duration, and gold nanoparticle radius. The full width at half maximum duration of the stress wave is almost constant up to a distance of 50 µm from the emission center. The stress wave amplitude is smaller than 5 MPa, while the stress wave duration is smaller than 35 ns. The stress wave propagation results in minor mechanical effects on biological tissue that are restricted to very small dimensions on a cellular or sub-cellular level. The stress wave is, however, able to produce breaching of the human cell membrane and bacterial wall even at distances as large as 50 µm from the emission centre. The experimentally observed melting of gold nanoparticles comes from the large temperature reached inside the nanoparticles during laser irradiation and not from the propagation of the stress wave into the surrounding liquid during nanobubble rebound.

Coherent control of alkali cluster fragmentation dynamics

NASA Astrophysics Data System (ADS)

Lindinger, Albrecht; Lupulescu, Cosmin; Bartelt, Andreas; Vajda, Štefan; Wöste, Ludger

2003-06-01

Metal clusters exhibit extraordinary chemical and catalytic properties, which sensitively depend upon their size. This behavior makes them interesting candidates for the real-time analysis of ultrafast photo-induced processes—ultimately leading to coherent control scenarii. We have performed transient multi-photon ionization experiments on small alkali clusters of different size in order to probe their wave packet dynamics, structural reorientations, charge transfers and dissociative events in different vibrationally excited electronic states including their ground state. The observed processes were highly dependent on the irradiated pulse parameters, like its phase, amplitude and duration; an emphasis to employ a feedback control system for generating the optimum pulse shapes. Their spectral and temporal behavior reflects interesting properties about the investigated system and the irradiated photochemical process. We present first the vibrational dynamics of bound, dissociated, and pre-dissociated electronically excited states of alkali dimers and trimers. The scheme for observing the wave packet dynamics in the electronic ground state using stimulated Raman-pumping is shown. Since the employed pulse parameters significantly influence the efficiency of the irradiated dynamic pathways photo-induced fragmentation experiments on bifurcating reaction channels were carried out. In these experiments different branching ionization and fragmentation pathways of electronically excited Na 2K were investigated. By employing an evolutionary algorithm for optimizing the phase and amplitude of the applied laser field, the yield of the resulting parent or fragment ions could significantly be influenced and interesting features could be concluded from the obtained optimum pulse shapes revealing the characteristic molecular oscillation period. Moreover, the influence on the optimal pulse shape due to fragmentation from larger clusters into NaK is obtained. The substructure of the optimal pulse shape thereby offers new insight into the fragmentation channel during the control process. Characteristic motions of the involved wave packets are proposed, in order to explain the optimized dynamic dissociation pathways.

Doppler indexes of left ventricular systolic and diastolic flow and central pulse pressure in relation to renal resistive index.

PubMed

Kuznetsova, Tatiana; Cauwenberghs, Nicholas; Knez, Judita; Thijs, Lutgarde; Liu, Yan-Ping; Gu, Yu-Mei; Staessen, Jan A

2015-04-01

The cardio-renal interaction occurs via hemodynamic and humoral factors. Noninvasive assessment of renal hemodynamics is currently possible by assessment of renal resistive index (RRI) derived from intrarenal Doppler arterial waveforms as ((peak systolic velocity - end-diastolic velocity)/peak systolic velocity). Limited information is available regarding the relationship between RRI and cardiac hemodynamics. We investigated these associations in randomly recruited subjects from a general population. In 171 participants (48.5% women; mean age, 52.2 years), using pulsed wave Doppler, we measured RRI (mean, 0.60) and left ventricular outflow tract (LVOT) and transmitral (E and A) blood flow peak velocities and its velocity time integrals (VTI). Using carotid applanation tonometry, we measured central pulse pressure and arterial stiffness indexes such as augmentation pressure and carotid-femoral pulse wave velocity. In stepwise regression analysis, RRI independently and significantly increased with female sex, age, body weight, brachial pulse pressure, and use of β-blockers, whereas it decreased with body height and mean arterial pressure. In multivariable-adjusted models with central pulse pressure and arterial stiffness indexes as the explanatory variables, we observed a significant and positive correlation of RRI only with central pulse pressure (P < 0.0001). Among the Doppler indexes of left ventricular blood flow, RRI was significantly and positively associated with LVOT and E peak velocities (P ≤ 0.012) and VTIs (P ≤ 0.010). We demonstrated that in unselected subjects RRI was significantly associated with central pulse pressure and left ventricular systolic and diastolic Doppler blood flow indexes. Our findings imply that in addition to the anthropometric characteristics, cardiac hemodynamic factors influence the intrarenal arterial Doppler waveform patterns. © American Journal of Hypertension, Ltd 2014. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Comparison between multi-channel LDV and PWI for measurement of pulse wave velocity in distensible tubes: Towards a new diagnostic technique for detection of arteriosclerosis

NASA Astrophysics Data System (ADS)

Campo, Adriaan; Dudzik, Grzegorz; Apostolakis, Jason; Waz, Adam; Nauleau, Pierre; Abramski, Krzysztof; Dirckx, Joris; Konofagou, Elisa

2017-10-01

The aim of this work, was to compare pulse wave velocity (PWV) measurements using Laser Doppler vibrometry (LDV) and the more established ultrasound-based pulse wave imaging (PWI) in smooth vessels. Additionally, it was tested whether changes in phantom structure can be detected using LDV in vessels containing a local hardening of the vessel wall. Results from both methods showed good agreement illustrated by the non-parametric Spearman correlation analysis (Spearman-ρ = 1 and p< 0.05) and the Bland-Altman analysis (mean bias of -0.63 m/s and limits of agreement between -0.35 and -0.90 m/s). The PWV in soft phantoms as measured with LDV was 1.30±0.40 m/s and the PWV in stiff phantoms was 3.6±1.4 m/s. The PWV values in phantoms with inclusions were in between those of soft and stiff phantoms. However, using LDV, given the low number of measurement beams, the exact locations of inclusions could not be determined, and the PWV in the inclusions could not be measured. In conclusion, this study indicates that the PWV as measured with PWI is in good agreement with the PWV measured with LDV although the latter technique has lower spatial resolution, fewer markers and larger distances between beams. In further studies, more LDV beams will be used to allow detection of local changes in arterial wall dynamics due to e.g. small inclusions or local hardenings of the vessel wall.

LIDAR pulse coding for high resolution range imaging at improved refresh rate.

PubMed

Kim, Gunzung; Park, Yongwan

2016-10-17

In this study, a light detection and ranging system (LIDAR) was designed that codes pixel location information in its laser pulses using the direct- sequence optical code division multiple access (DS-OCDMA) method in conjunction with a scanning-based microelectromechanical system (MEMS) mirror. This LIDAR can constantly measure the distance without idle listening time for the return of reflected waves because its laser pulses include pixel location information encoded by applying the DS-OCDMA. Therefore, this emits in each bearing direction without waiting for the reflected wave to return. The MEMS mirror is used to deflect and steer the coded laser pulses in the desired bearing direction. The receiver digitizes the received reflected pulses using a low-temperature-grown (LTG) indium gallium arsenide (InGaAs) based photoconductive antenna (PCA) and the time-to-digital converter (TDC) and demodulates them using the DS-OCDMA. When all of the reflected waves corresponding to the pixels forming a range image are received, the proposed LIDAR generates a point cloud based on the time-of-flight (ToF) of each reflected wave. The results of simulations performed on the proposed LIDAR are compared with simulations of existing LIDARs.

Simultaneous manipulation and observation of multiple ro-vibrational eigenstates in solid para-hydrogen.

PubMed

Katsuki, Hiroyuki; Ohmori, Kenji

2016-09-28

We have experimentally performed the coherent control of delocalized ro-vibrational wave packets (RVWs) of solid para-hydrogen (p-H 2 ) by the wave packet interferometry (WPI) combined with coherent anti-Stokes Raman scattering (CARS). RVWs of solid p-H 2 are delocalized in the crystal, and the wave function with wave vector k ∼ 0 is selectively excited via the stimulated Raman process. We have excited the RVW twice by a pair of femtosecond laser pulses with delay controlled by a stabilized Michelson interferometer. Using a broad-band laser pulse, multiple ro-vibrational states can be excited simultaneously. We have observed the time-dependent Ramsey fringe spectra as a function of the inter-pulse delay by a spectrally resolved CARS technique using a narrow-band probe pulse, resolving the different intermediate states. Due to the different fringe oscillation periods among those intermediate states, we can manipulate their amplitude ratio by tuning the inter-pulse delay on the sub-femtosecond time scale. The state-selective manipulation and detection of the CARS signal combined with the WPI is a general and efficient protocol for the control of the interference of multiple quantum states in various quantum systems.

Relationships among the serum omega fatty acid levels, serum C-reactive protein levels and arterial stiffness/wave reflection in Japanese men.

PubMed

Tomiyama, Hirofumi; Matsumoto, Chisa; Odaira, Mari; Yamada, Jiko; Yoshida, Masanobu; Shiina, Kazuki; Nagata, Mikio; Yamashina, Akira

2011-08-01

We examined the relationship among the serum omega-3 and omega-6 fatty acid (O3FA and O6FA) levels, serum C-reactive protein (CRP) levels, and arterial stiffness/wave reflection (AS/WR) in healthy Japanese men. In 2206 Japanese healthy men, parameters related to the AS/WR (i.e., brachial-ankle pulse wave velocity and radial arterial pulse wave analysis) were measured. No significant inverse relationships were observed between the serum O3FA levels and the AS/WR-related parameters. Adjusted values of the AS/WR-related parameters and serum CRP levels were higher in the subjects with serum O6FA levels in the highest tertile than in those with serum O6FA levels in the lowest tertile. In healthy Japanese men with known high dietary intakes of O3FAs, the serum O3FA levels may not reflect the pathophysiological abnormalities related to AS/WR. Increased serum O6FA levels appeared to be independently associated with the unfavorable conditions related to AS/WR and inflammation. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

Empirical transfer functions: Application to the determination of outermost core velocity structure using teleseismic SmKS phases

NASA Astrophysics Data System (ADS)

Eaton, D. W.; Alexandrakis, C.

2007-05-01

Teleseismic SmKS waves propagate as S-waves in the mantle and compressional (K) waves in the core, with m-1 underside bounce points at the core-mantle boundary. For long-period or broadband recordings at epicentral distances of 115-135°, higher-order SmKS waves (3 ≤ m < ∞) are not often discernible as distinct pulses. Instead, they are typically manifested as a weakly dispersive waveform that lags SKKS by ~ 12-32s. In a ray-theoretical representation of this process, there is a strong geometrical similarity between the coalescence of SmKS turning waves to form a composite arrival and the interference of mantle S waves to form teleseismic Love waves. SmKS waves can thus be viewed as a type of pseudo-interface wave, the dispersive properties of which depend strongly on the fine-scale velocity structure of the outermost core. In order to analyze SmKS arrivals, we have developed an empirical transfer-function (ETF) technique that uses SKKS as a reference phase. An ETF is a wave-shaping filter that transforms the observed SKKS pulse into the observed SmKS pulse. We obtain this filter by windowing the respective pulses and applying frequency- domain Wiener deconvolution. Each ETF contains SmKS-SKKS differential arrival-time, phase-shift and relative-amplitude information; it also implicitly removes the source-time function and instrument response, thus facilitating the merging of results from different stations and events. Here, we apply this approach to global observations of SmKS phases and invert the results to yield a new velocity model for the outermost core region.

Few-cycle optical rogue waves: complex modified Korteweg-de Vries equation.

PubMed

He, Jingsong; Wang, Lihong; Li, Linjing; Porsezian, K; Erdélyi, R

2014-06-01

In this paper, we consider the complex modified Korteweg-de Vries (mKdV) equation as a model of few-cycle optical pulses. Using the Lax pair, we construct a generalized Darboux transformation and systematically generate the first-, second-, and third-order rogue wave solutions and analyze the nature of evolution of higher-order rogue waves in detail. Based on detailed numerical and analytical investigations, we classify the higher-order rogue waves with respect to their intrinsic structure, namely, fundamental pattern, triangular pattern, and ring pattern. We also present several new patterns of the rogue wave according to the standard and nonstandard decomposition. The results of this paper explain the generalization of higher-order rogue waves in terms of rational solutions. We apply the contour line method to obtain the analytical formulas of the length and width of the first-order rogue wave of the complex mKdV and the nonlinear Schrödinger equations. In nonlinear optics, the higher-order rogue wave solutions found here will be very useful to generate high-power few-cycle optical pulses which will be applicable in the area of ultrashort pulse technology.

Composite rogue waves and modulation instability for the three-coupled Hirota system in an optical fiber

NASA Astrophysics Data System (ADS)

Chai, Han-Peng; Tian, Bo; Chai, Jun; Du, Zhong

2017-10-01

We investigate the three-coupled Hirota system, which is applied to model the long distance communication and ultrafast signal routing systems governing the propagation of light pulses. With the aid of the Darboux dressing transformation, composite rogue wave solutions are derived. Spatial-temporal structures, including the four-petaled structure for the three-coupled Hirota system, are exhibited. We find that the four-petaled rogue waves occur in two of the three components, whereas the eye-shaped rogue wave occurs in the other one. The composite rogue waves can split up into two or three single rogue waves. The corresponding conditions for the occurrence of such phenomena are discussed and presented. We find that the relative position of every single rogue wave is influenced by the ratios of certain parameters. Besides, the linear instability analysis is performed, and our results agree with those from the baseband modulation instability theory.

RADIATION WAVE DETECTION

DOEpatents

Wouters, L.F.

1960-08-30

Radiation waves can be detected by simultaneously measuring radiation- wave intensities at a plurality of space-distributed points and producing therefrom a plot of the wave intensity as a function of time. To this end. a detector system is provided which includes a plurality of nuclear radiation intensity detectors spaced at equal radial increments of distance from a source of nuclear radiation. Means are provided to simultaneously sensitize the detectors at the instant a wave of radiation traverses their positions. the detectors producing electrical pulses indicative of wave intensity. The system further includes means for delaying the pulses from the detectors by amounts proportional to the distance of the detectors from the source to provide an indication of radiation-wave intensity as a function of time.

Extremely High Peak Power Obtained at 29 GHZ Microwave Pulse Generation

NASA Astrophysics Data System (ADS)

Rostov, V. V.; Gunin, A. V.; Romanchenko, I. V.; Pedos, M. S.; Rukin, S. N.; Sharypov, K. A.; Shunailov, S. A.; Ul'maskulov, M. R.; Yalandin, M. I.

2017-12-01

The paper presents research results on enhancing the peak power of microwave pulses with sub- and nanosecond length using a backward-wave oscillator (BWO) operating at 29 GHz frequency and possessing a reproducible phase structure. Experiments are conducted in two modes on a high-current electron accelerator with the required electron beam power. In the first (superradiation) mode, which utilizes the elongated slow-wave structure, the BWO peak power is 3 GW at 180 ns pulse duration (full width at halfmaximum, FWHM). In the second (quasi-stationary) mode, the BWO peak power reaches 600 MW at 2 ns pulse duration (FWHM). The phase spread from pulse to pulse can vary from units to several tens of percent in a nanosecond pulse mode. The experiments do not show any influence of microwave breakdown on the BWO power generation and radiation pulse duration.

L wave in echo Doppler.

PubMed

Kumar, Vipin; Jose, John; Jose, V Jacob

2014-01-01

62-year-old female presented with progressive dyspnea NYHA class III for six months. Echocardiography showed normal left ventricular (LV) systolic function, mild biatrial enlargement, an L wave in pulse wave Doppler at mitral inflow and in M mode echocardiography across mitral valve. Tissue Doppler imaging at medial mitral annulus showed an L' wave in mid diastole in addition to E' and A' wave. An L wave in pulse wave Doppler and M mode echocardiography represents continued pulmonary vein mid diastolic flow through the left atrium in to LV across mitral valve after early rapid filling. Presence of an L' wave in these patients associated with higher E/E' is indicative of advance diastolic dysfunction with elevated filling pressures. Copyright © 2014 Cardiological Society of India. Published by Elsevier B.V. All rights reserved.

Search for transient gravitational waves in coincidence with short-duration radio transients during 2007-2013

NASA Astrophysics Data System (ADS)

Abbott, B. P.; Abbott, R.; Abbott, T. D.; Abernathy, M. R.; Acernese, F.; Ackley, K.; Adams, C.; Adams, T.; Addesso, P.; Adhikari, R. X.; Adya, V. B.; Affeldt, C.; Agathos, M.; Agatsuma, K.; Aggarwal, N.; Aguiar, O. D.; Aiello, L.; Ain, A.; Ajith, P.; Allen, B.; Allocca, A.; Altin, P. A.; Anderson, S. B.; Anderson, W. G.; Arai, K.; Araya, M. C.; Arceneaux, C. C.; Areeda, J. S.; Arnaud, N.; Arun, K. G.; Ascenzi, S.; Ashton, G.; Ast, M.; Aston, S. M.; Astone, P.; Aufmuth, P.; Aulbert, C.; Babak, S.; Bacon, P.; Bader, M. K. M.; Baker, P. T.; Baldaccini, F.; Ballardin, G.; Ballmer, S. W.; Barayoga, J. C.; Barclay, S. E.; Barish, B. C.; Barker, D.; Barone, F.; Barr, B.; Barsotti, L.; Barsuglia, M.; Barta, D.; Bartlett, J.; Bartos, I.; Bassiri, R.; Basti, A.; Batch, J. C.; Baune, C.; Bavigadda, V.; Bazzan, M.; Behnke, B.; Bejger, M.; Bell, A. S.; Bell, C. J.; Berger, B. K.; Bergman, J.; Bergmann, G.; Berry, C. P. L.; Bersanetti, D.; Bertolini, A.; Betzwieser, J.; Bhagwat, S.; Bhandare, R.; Bilenko, I. A.; Billingsley, G.; Birch, J.; Birney, R.; Biscans, S.; Bisht, A.; Bitossi, M.; Biwer, C.; Bizouard, M. A.; Blackburn, J. K.; Blair, C. D.; Blair, D. G.; Blair, R. M.; Bloemen, S.; Bock, O.; Bodiya, T. P.; Boer, M.; Bogaert, G.; Bogan, C.; Bohe, A.; Bojtos, P.; Bond, C.; Bondu, F.; Bonnand, R.; Boom, B. A.; Bork, R.; Boschi, V.; Bose, S.; Bouffanais, Y.; Bozzi, A.; Bradaschia, C.; Brady, P. R.; Braginsky, V. B.; Branchesi, M.; Brau, J. E.; Briant, T.; Brillet, A.; Brinkmann, M.; Brisson, V.; Brockill, P.; Brooks, A. F.; Brown, D. A.; Brown, D. D.; Brown, N. M.; Buchanan, C. C.; Buikema, A.; Bulik, T.; Bulten, H. J.; Buonanno, A.; Buskulic, D.; Buy, C.; Byer, R. L.; Cadonati, L.; Cagnoli, G.; Cahillane, C.; Calderón Bustillo, J.; Callister, T.; Calloni, E.; Camp, J. B.; Cannon, K. C.; Cao, J.; Capano, C. D.; Capocasa, E.; Carbognani, F.; Caride, S.; Casanueva Diaz, J.; Casentini, C.; Caudill, S.; Cavaglià, M.; Cavalier, F.; Cavalieri, R.; Cella, G.; Cepeda, C. B.; Cerboni Baiardi, L.; Cerretani, G.; Cesarini, E.; Chakraborty, R.; Chalermsongsak, T.; Chamberlin, S. J.; Chan, M.; Chao, S.; Charlton, P.; Chassande-Mottin, E.; Chen, H. Y.; Chen, Y.; Cheng, C.; Chincarini, A.; Chiummo, A.; Cho, H. S.; Cho, M.; Chow, J. H.; Christensen, N.; Chu, Q.; Chua, S.; Chung, S.; Ciani, G.; Clara, F.; Clark, J. A.; Cleva, F.; Coccia, E.; Cohadon, P.-F.; Colla, A.; Collette, C. G.; Cominsky, L.; Constancio, M.; Conte, A.; Conti, L.; Cook, D.; Corbitt, T. R.; Cornish, N.; Corsi, A.; Cortese, S.; Costa, C. A.; Coughlin, M. W.; Coughlin, S. B.; Coulon, J.-P.; Countryman, S. T.; Couvares, P.; Coward, D. M.; Cowart, M. J.; Coyne, D. C.; Coyne, R.; Craig, K.; Creighton, J. D. E.; Cripe, J.; Crowder, S. G.; Cumming, A.; Cunningham, L.; Cuoco, E.; Dal Canton, T.; Danilishin, S. L.; D'Antonio, S.; Danzmann, K.; Darman, N. S.; Dattilo, V.; Dave, I.; Daveloza, H. P.; Davier, M.; Davies, G. S.; Daw, E. J.; Day, R.; DeBra, D.; Debreczeni, G.; Degallaix, J.; De Laurentis, M.; Deléglise, S.; Del Pozzo, W.; Denker, T.; Dent, T.; Dergachev, V.; De Rosa, R.; DeRosa, R. T.; DeSalvo, R.; Dhurandhar, S.; Díaz, M. C.; Di Fiore, L.; Di Giovanni, M.; Di Girolamo, T.; Di Lieto, A.; Di Pace, S.; Di Palma, I.; Di Virgilio, A.; Dojcinoski, G.; Dolique, V.; Donovan, F.; Dooley, K. L.; Doravari, S.; Douglas, R.; Downes, T. P.; Drago, M.; Drever, R. W. P.; Driggers, J. C.; Du, Z.; Ducrot, M.; Dwyer, S. E.; Edo, T. B.; Edwards, M. C.; Effler, A.; Eggenstein, H.-B.; Ehrens, P.; Eichholz, J.; Eikenberry, S. S.; Engels, W.; Essick, R. C.; Etzel, T.; Evans, M.; Evans, T. M.; Everett, R.; Factourovich, M.; Fafone, V.; Fair, H.; Fairhurst, S.; Fan, X.; Fang, Q.; Farinon, S.; Farr, B.; Farr, W. M.; Favata, M.; Fays, M.; Fehrmann, H.; Fejer, M. M.; Ferrante, I.; Ferreira, E. C.; Ferrini, F.; Fidecaro, F.; Fiori, I.; Fiorucci, D.; Fisher, R. P.; Flaminio, R.; Fletcher, M.; Fournier, J.-D.; Frasca, S.; Frasconi, F.; Frei, Z.; Freise, A.; Frey, R.; Frey, V.; Fricke, T. T.; Fritschel, P.; Frolov, V. V.; Fulda, P.; Fyffe, M.; Gabbard, H. A. G.; Gair, J. R.; Gammaitoni, L.; Gaonkar, S. G.; Garufi, F.; Gaur, G.; Gehrels, N.; Gemme, G.; Genin, E.; Gennai, A.; George, J.; Gergely, L.; Germain, V.; Ghosh, Archisman; Ghosh, S.; Giaime, J. A.; Giardina, K. D.; Giazotto, A.; Gill, K.; Glaefke, A.; Goetz, E.; Goetz, R.; Gondan, L.; González, G.; Gonzalez Castro, J. M.; Gopakumar, A.; Gordon, N. A.; Gorodetsky, M. L.; Gossan, S. E.; Gosselin, M.; Gouaty, R.; Grado, A.; Graef, C.; Graff, P. B.; Granata, M.; Grant, A.; Gras, S.; Gray, C.; Greco, G.; Green, A. C.; Groot, P.; Grote, H.; Grunewald, S.; Guidi, G. M.; Guo, X.; Gupta, A.; Gupta, M. K.; Gushwa, K. E.; Gustafson, E. K.; Gustafson, R.; Hacker, J. J.; Hall, B. R.; Hall, E. D.; Hammond, G.; Haney, M.; Hanke, M. M.; Hanks, J.; Hanna, C.; Hannam, M. D.; Hanson, J.; Hardwick, T.; Harms, J.; Harry, G. M.; Harry, I. W.; Hart, M. J.; Hartman, M. T.; Haster, C.-J.; Haughian, K.; Heidmann, A.; Heintze, M. C.; Heitmann, H.; Hello, P.; Hemming, G.; Hendry, M.; Heng, I. S.; Hennig, J.; Heptonstall, A. W.; Heurs, M.; Hild, S.; Hoak, D.; Hodge, K. A.; Hofman, D.; Hollitt, S. E.; Holt, K.; Holz, D. E.; Hopkins, P.; Hosken, D. J.; Hough, J.; Houston, E. A.; Howell, E. J.; Hu, Y. M.; Huang, S.; Huerta, E. A.; Huet, D.; Hughey, B.; Husa, S.; Huttner, S. H.; Huynh-Dinh, T.; Idrisy, A.; Indik, N.; Ingram, D. R.; Inta, R.; Isa, H. N.; Isac, J.-M.; Isi, M.; Islas, G.; Isogai, T.; Iyer, B. R.; Izumi, K.; Jacqmin, T.; Jang, H.; Jani, K.; Jaranowski, P.; Jawahar, S.; Jiménez-Forteza, F.; Johnson, W. W.; Jones, D. I.; Jones, R.; Jonker, R. J. G.; Ju, L.; Haris, K.; Kalaghatgi, C. V.; Kalogera, V.; Kandhasamy, S.; Kang, G.; Kanner, J. B.; Karki, S.; Kasprzack, M.; Katsavounidis, E.; Katzman, W.; Kaufer, S.; Kaur, T.; Kawabe, K.; Kawazoe, F.; Kéfélian, F.; Kehl, M. S.; Keitel, D.; Kelley, D. B.; Kells, W.; Kennedy, R.; Key, J. S.; Khalaidovski, A.; Khalili, F. Y.; Khan, I.; Khan, S.; Khan, Z.; Khazanov, E. A.; Kijbunchoo, N.; Kim, Chunglee; Kim, J.; Kim, K.; Kim, Nam-Gyu; Kim, Namjun; Kim, Y.-M.; King, E. J.; King, P. J.; Kinzel, D. L.; Kissel, J. S.; Kleybolte, L.; Klimenko, S.; Koehlenbeck, S. M.; Kokeyama, K.; Koley, S.; Kondrashov, V.; Kontos, A.; Korobko, M.; Korth, W. Z.; Kowalska, I.; Kozak, D. B.; Kringel, V.; Królak, A.; Krueger, C.; Kuehn, G.; Kumar, P.; Kuo, L.; Kutynia, A.; Lackey, B. D.; Landry, M.; Lange, J.; Lantz, B.; Lasky, P. D.; Lazzarini, A.; Lazzaro, C.; Leaci, P.; Leavey, S.; Lebigot, E. O.; Lee, C. H.; Lee, H. K.; Lee, H. M.; Lee, K.; Lenon, A.; Leonardi, M.; Leong, J. R.; Leroy, N.; Letendre, N.; Levin, Y.; Levine, B. M.; Li, T. G. F.; Libson, A.; Littenberg, T. B.; Lockerbie, N. A.; Logue, J.; Lombardi, A. L.; Lord, J. E.; Lorenzini, M.; Loriette, V.; Lormand, M.; Losurdo, G.; Lough, J. D.; Lück, H.; Lundgren, A. P.; Luo, J.; Lynch, R.; Ma, Y.; MacDonald, T.; Machenschalk, B.; MacInnis, M.; Macleod, D. M.; Magaña-Sandoval, F.; Magee, R. M.; Mageswaran, M.; Majorana, E.; Maksimovic, I.; Malvezzi, V.; Man, N.; Mandic, V.; Mangano, V.; Mansell, G. L.; Manske, M.; Mantovani, M.; Marchesoni, F.; Marion, F.; Márka, S.; Márka, Z.; Markosyan, A. S.; Maros, E.; Martelli, F.; Martellini, L.; Martin, I. W.; Martin, R. M.; Martynov, D. V.; Marx, J. N.; Mason, K.; Masserot, A.; Massinger, T. J.; Masso-Reid, M.; Mastrogiovanni, S.; Matichard, F.; Matone, L.; Mavalvala, N.; Mazumder, N.; Mazzolo, G.; McCarthy, R.; McClelland, D. E.; McCormick, S.; McGuire, S. C.; McIntyre, G.; McIver, J.; McManus, D. J.; McWilliams, S. T.; Meacher, D.; Meadors, G. D.; Meidam, J.; Melatos, A.; Mendell, G.; Mendoza-Gandara, D.; Mercer, R. A.; Merilh, E. L.; Merzougui, M.; Meshkov, S.; Messenger, C.; Messick, C.; Metzdorff, R.; Meyers, P. M.; Mezzani, F.; Miao, H.; Michel, C.; Middleton, H.; Mikhailov, E. E.; Milano, L.; Miller, A. L.; Miller, J.; Millhouse, M.; Minenkov, Y.; Ming, J.; Mirshekari, S.; Mishra, C.; Mitra, S.; Mitrofanov, V. P.; Mitselmakher, G.; Mittleman, R.; Moggi, A.; Mohan, M.; Mohapatra, S. R. P.; Montani, M.; Moore, B. C.; Moore, C. J.; Moraru, D.; Moreno, G.; Morriss, S. R.; Mossavi, K.; Mours, B.; Mow-Lowry, C. M.; Mueller, C. L.; Mueller, G.; Muir, A. W.; Mukherjee, Arunava; Mukherjee, D.; Mukherjee, S.; Mukund, K. N.; Mullavey, A.; Munch, J.; Murphy, D. J.; Murray, P. G.; Mytidis, A.; Nardecchia, I.; Naticchioni, L.; Nayak, R. K.; Necula, V.; Nedkova, K.; Nelemans, G.; Neri, M.; Neunzert, A.; Newton, G.; Nguyen, T. T.; Nielsen, A. B.; Nissanke, S.; Nitz, A.; Nocera, F.; Nolting, D.; Normandin, M. E. N.; Nuttall, L. K.; Oberling, J.; Ochsner, E.; O'Dell, J.; Oelker, E.; Ogin, G. H.; Oh, J. J.; Oh, S. H.; Ohme, F.; Oliver, M.; Oppermann, P.; Oram, Richard J.; O'Reilly, B.; O'Shaughnessy, R.; Ott, C. D.; Ottaway, D. J.; Ottens, R. S.; Overmier, H.; Owen, B. J.; Pai, A.; Pai, S. A.; Palamos, J. R.; Palashov, O.; Palomba, C.; Pal-Singh, A.; Pan, H.; Pankow, C.; Pannarale, F.; Pant, B. C.; Paoletti, F.; Paoli, A.; Papa, M. A.; Paris, H. R.; Parker, W.; Pascucci, D.; Pasqualetti, A.; Passaquieti, R.; Passuello, D.; Patricelli, B.; Patrick, Z.; Pearlstone, B. L.; Pedraza, M.; Pedurand, R.; Pekowsky, L.; Pele, A.; Penn, S.; Pereira, R.; Perreca, A.; Phelps, M.; Piccinni, O. J.; Pichot, M.; Piergiovanni, F.; Pierro, V.; Pillant, G.; Pinard, L.; Pinto, I. M.; Pitkin, M.; Pletsch, H. J.; Poggiani, R.; Popolizio, P.; Post, A.; Powell, J.; Prasad, J.; Predoi, V.; Premachandra, S. S.; Prestegard, T.; Price, L. R.; Prijatelj, M.; Principe, M.; Privitera, S.; Prodi, G. A.; Prokhorov, L.; Puncken, O.; Punturo, M.; Puppo, P.; Pürrer, M.; Qi, H.; Qin, J.; Quetschke, V.; Quintero, E. A.; Quitzow-James, R.; Raab, F. J.; Rabeling, D. S.; Radkins, H.; Raffai, P.; Raja, S.; Rakhmanov, M.; Rapagnani, P.; Raymond, V.; Razzano, M.; Re, V.; Read, J.; Reed, C. M.; Regimbau, T.; Rei, L.; Reid, S.; Reitze, D. H.; Rew, H.; Ricci, F.; Riles, K.; Robertson, N. A.; Robie, R.; Robinet, F.; Rocchi, A.; Rolland, L.; Rollins, J. G.; Roma, V. J.; Romano, J. D.; Romano, R.; Romanov, G.; Romie, J. H.; Rosińska, D.; Rowan, S.; Rüdiger, A.; Ruggi, P.; Ryan, K.; Sachdev, S.; Sadecki, T.; Sadeghian, L.; Salconi, L.; Saleem, M.; Salemi, F.; Samajdar, A.; Sammut, L.; Sanchez, E. J.; Sandberg, V.; Sandeen, B.; Sanders, J. R.; Sassolas, B.; Sathyaprakash, B. S.; Saulson, P. R.; Sauter, O. E. S.; Savage, R. L.; Sawadsky, A.; Schale, P.; Schilling, R.; Schmidt, J.; Schmidt, P.; Schnabel, R.; Schofield, R. M. S.; Schönbeck, A.; Schreiber, E.; Schuette, D.; Schutz, B. F.; Scott, J.; Scott, S. M.; Sellers, D.; Sentenac, D.; Sequino, V.; Sergeev, A.; Serna, G.; Setyawati, Y.; Sevigny, A.; Shaddock, D. A.; Shahriar, M. S.; Shaltev, M.; Shao, Z.; Shapiro, B.; Shawhan, P.; Sheperd, A.; Shoemaker, D. H.; Shoemaker, D. M.; Siellez, K.; Siemens, X.; Sieniawska, M.; Sigg, D.; Silva, A. D.; Simakov, D.; Singer, A.; Singer, L. P.; Singh, A.; Singh, R.; Singhal, A.; Sintes, A. M.; Slagmolen, B. J. J.; Smith, J. R.; Smith, N. D.; Smith, R. J. E.; Son, E. J.; Sorazu, B.; Sorrentino, F.; Souradeep, T.; Srivastava, A. K.; Staley, A.; Steinke, M.; Steinlechner, J.; Steinlechner, S.; Steinmeyer, D.; Stephens, B. C.; Stiles, D.; Stone, R.; Strain, K. A.; Straniero, N.; Stratta, G.; Strauss, N. A.; Strigin, S.; Sturani, R.; Stuver, A. L.; Summerscales, T. Z.; Sun, L.; Sutton, P. J.; Swinkels, B. L.; Szczepańczyk, M. J.; Tacca, M.; Talukder, D.; Tanner, D. B.; Tápai, M.; Tarabrin, S. P.; Taracchini, A.; Taylor, R.; Theeg, T.; Thirugnanasambandam, M. P.; Thomas, E. G.; Thomas, M.; Thomas, P.; Thorne, K. A.; Thrane, E.; Tiwari, S.; Tiwari, V.; Tokmakov, K. V.; Tomlinson, C.; Tonelli, M.; Torres, C. V.; Torrie, C. I.; Töyrä, D.; Travasso, F.; Traylor, G.; Trifirò, D.; Tringali, M. C.; Trozzo, L.; Tse, M.; Turconi, M.; Tuyenbayev, D.; Ugolini, D.; Unnikrishnan, C. S.; Urban, A. L.; Usman, S. A.; Vahlbruch, H.; Vajente, G.; Valdes, G.; van Bakel, N.; van Beuzekom, M.; van den Brand, J. F. J.; Van Den Broeck, C.; Vander-Hyde, D. C.; van der Schaaf, L.; van Heijningen, J. V.; van Veggel, A. A.; Vardaro, M.; Vass, S.; Vasúth, M.; Vaulin, R.; Vecchio, A.; Vedovato, G.; Veitch, J.; Veitch, P. J.; Venkateswara, K.; Verkindt, D.; Vetrano, F.; Viceré, A.; Vinciguerra, S.; Vine, D. J.; Vinet, J.-Y.; Vitale, S.; Vo, T.; Vocca, H.; Vorvick, C.; Voss, D. V.; Vousden, W. D.; Vyatchanin, S. P.; Wade, A. R.; Wade, L. E.; Wade, M.; Walker, M.; Wallace, L.; Walsh, S.; Wang, G.; Wang, H.; Wang, M.; Wang, X.; Wang, Y.; Ward, R. L.; Warner, J.; Was, M.; Weaver, B.; Wei, L.-W.; Weinert, M.; Weinstein, A. J.; Weiss, R.; Welborn, T.; Wen, L.; Weßels, P.; Westphal, T.; Wette, K.; Whelan, J. T.; Whitcomb, S. E.; White, D. J.; Whiting, B. F.; Williams, R. D.; Williamson, A. R.; Willis, J. L.; Willke, B.; Wimmer, M. H.; Winkler, W.; Wipf, C. C.; Wittel, H.; Woan, G.; Worden, J.; Wright, J. L.; Wu, G.; Yablon, J.; Yam, W.; Yamamoto, H.; Yancey, C. C.; Yap, M. J.; Yu, H.; Yvert, M.; ZadroŻny, A.; Zangrando, L.; Zanolin, M.; Zendri, J.-P.; Zevin, M.; Zhang, F.; Zhang, L.; Zhang, M.; Zhang, Y.; Zhao, C.; Zhou, M.; Zhou, Z.; Zhu, X. J.; Zucker, M. E.; Zuraw, S. E.; Zweizig, J.; Archibald, A. M.; Banaszak, S.; Berndsen, A.; Boyles, J.; Cardoso, R. F.; Chawla, P.; Cherry, A.; Dartez, L. P.; Day, D.; Epstein, C. R.; Ford, A. J.; Flanigan, J.; Garcia, A.; Hessels, J. W. T.; Hinojosa, J.; Jenet, F. A.; Karako-Argaman, C.; Kaspi, V. M.; Keane, E. F.; Kondratiev, V. I.; Kramer, M.; Leake, S.; Lorimer, D.; Lunsford, G.; Lynch, R. S.; Martinez, J. G.; Mata, A.; McLaughlin, M. A.; McPhee, C. A.; Penucci, T.; Ransom, S.; Roberts, M. S. E.; Rohr, M. D. W.; Stairs, I. H.; Stovall, K.; van Leeuwen, J.; Walker, A. N.; Wells, B. L.; LIGO Scientific Collaboration; Virgo Collaboration

2016-06-01

We present an archival search for transient gravitational-wave bursts in coincidence with 27 single-pulse triggers from Green Bank Telescope pulsar surveys, using the LIGO, Virgo, and GEO interferometer network. We also discuss a check for gravitational-wave signals in coincidence with Parkes fast radio bursts using similar methods. Data analyzed in these searches were collected between 2007 and 2013. Possible sources of emission of both short-duration radio signals and transient gravitational-wave emission include starquakes on neutron stars, binary coalescence of neutron stars, and cosmic string cusps. While no evidence for gravitational-wave emission in coincidence with these radio transients was found, the current analysis serves as a prototype for similar future searches using more sensitive second-generation interferometers.

Effect of electromagnetic pulse on avoidance behavior and electroencephalogram of a rhesus monkey.

PubMed

Mattsson, J L; Oliva, S A

1976-06-01

A 12-kg male rhesus monkey was exposed to electromagnetic pulse (EMP) at 266 kv/m, 5 pulses/s, for 1 h (18,700 pulses). The effects of EMP on Sidman avoidance behavior and on post-exposure electroencephalogram were evaluated, and no significant changes were detected. An analysis of an EMP showed that it contained various frequency components extending from 0 Hz to 10(9) Hz. However, the pulse configuration was such that its power was mainly confined to the longer wave-lengths (less than 30 MHz). The lack of biologic effect was attributed to the fact that the wavelengths were long relative to the size of the monkey, and little energy deposition was likely to occur. In addition, the electric field was evenly distributed across all lower frequencies so that only a very small electric field component existed at any specific low frequency.

Dynamic behavior of geometrically complex hybrid composite samples in a Split-Hopkinson Pressure Bar system

NASA Astrophysics Data System (ADS)

Pouya, M.; Balasubramaniam, S.; Sharafiev, S.; F-X Wagner, M.

2018-06-01

The interfaces between layered materials play an important role for the overall mechanical behavior of hybrid composites, particularly during dynamic loading. Moreover, in complex-shaped composites, interfacial failure is strongly affected by the geometry and size of these contact interfaces. As preliminary work for the design of a novel sample geometry that allows to analyze wave reflection phenomena at the interfaces of such materials, a series of experiments using a Split-Hopkinson Pressure Bar technique was performed on five different sample geometries made of a monomaterial steel. A complementary explicit finite element model of the Split-Hopkinson Pressure Bar system was developed and the same sample geometries were studied numerically. The simulated input, reflected and transmitted elastic wave pulses were analyzed for the different sample geometries and were found to agree well with the experimental results. Additional simulations using different composite layers of steel and aluminum (with the same sample geometries) were performed to investigate the effect of material variation on the propagated wave pulses. The numerical results show that the reflected and transmitted wave pulses systematically depend on the sample geometry, and that elastic wave pulse propagation is affected by the properties of individual material layers.

Nonlinear interaction of infrared waves on a VO2 surface at a semiconductor-metal phase transition

NASA Astrophysics Data System (ADS)

Berger, N. K.; Zhukov, E. A.; Novokhatskii, V. V.

1984-04-01

Nonlinear interactions (including wavefront reversal) of light from CW or pulsed 10.6-micron CO2 lasers at the semiconductor-metal phase transition in a VO2 film are investigated experimentally. The results are presented in graphs and characterized in detail. The intensity reflection coefficients of the three-wave interactions are found to be 0.5 percent for a CW reference wave of intensity 900 mW/sq cm and 42 percent for a pulsed reference wave of threshold density 600-800 microjoule/sq cm.

A Study of Electron and Phonon Dynamics by Broadband Two-Dimensional THz Time-Domain Spectroscopy

NASA Astrophysics Data System (ADS)

Fu, Zhengping

Terahertz (THz) wave interacts with semiconductors in many ways, such as resonant excitation of lattice vibration, intraband transition and polaron formation. Different from the optical waves, THz wave has lower photon energy (1 THz = 4.14 meV) and is suitable for studying dynamics of low-energy excitations. Recently the studies of the interaction of THz wave and semiconductors have been extending from the linear regime to the nonlinear regime, owing to the advance of the high-intensity THz generation and detection methods. Two-dimensional (2D) spectroscopy, as a useful tool to unravel the nonlinearity of materials, has been well developed in nuclear magnetic resonance and infrared region. However, the counterpart in THz region has not been well developed and was only demonstrated at frequency around 20 THz due to the lack of intense broadband THz sources. Using laser-induced plasma as the THz source, we developed collinear broadband 2D THz time-domain spectroscopy covering from 0.5 THz to 20 THz. Broadband intense THz pulses emitted from laser-induced plasma provide access to a variety of nonlinear properties of materials. Ultrafast optical and THz pulses make it possible to resolve the transient change of the material properties with temporal resolution of tens of femtoseconds. This thesis focuses on the linear and nonlinear interaction of the THz wave with semiconductors. Since a great many physical processes, including vibrational motion of lattice and plasma oscillation, has resonant frequency in the THz range, rich physics can be studies in our experiment. The thesis starts from the linear interaction of the THz wave with semiconductors. In the narrow band gap semiconductor InSb, the plasma absorption edge, Restrahlen band and dispersion of polaritons are observed. The nonlinear response of InSb in high THz field is verified in the frequency-resolved THz Z-scan experiment. The third harmonic generations due to the anharmonicity of plasma oscillation and the second order signal due to the plasma-phonon interaction are observed in 2D THz transmission spectra. In this thesis, the coherent phonons excited by THz pulses are experimentally demonstrated for the first time in both GaAs and InSb. The resonant excitation using THz pulses enables the coherent control of the lattice motion via direct interaction of atoms and electromagnetic wave, without inducing electronic transition as reported in the optical excitation of coherent phonons. The classic model is used to explain both excitation and detection mechanisms. An increase of the damping rate of the coherent lattice motion due to higher carrier density is observed in our experiment. Transient reflectivity change of GaAs induced by THz pulses is studied in 2D THz-pump/optical-probe configuration. Using the perturbative analysis of nonlinear electrooptic effect, we conclude that the nonlinear response of GaAs to two phase-locked THz pulses is mainly caused by the nonlinearity of the electronic response.

Nonlinear pulse propagation and phase velocity of laser-driven plasma waves

NASA Astrophysics Data System (ADS)

Benedetti, Carlo; Rossi, Francesco; Schroeder, Carl; Esarey, Eric; Leemans, Wim

2014-10-01

We investigate and characterize the laser evolution and plasma wave excitation by a relativistically intense, short-pulse laser propagating in a preformed parabolic plasma channel, including the effects of pulse steepening, frequency redshifting, and energy depletion. We derived in 3D, and in the weakly relativistic intensity regime, analytical expressions for the laser energy depletion, the pulse self-steepening rate, the laser intensity centroid velocity, and the phase velocity of the plasma wave. Analytical results have been validated numerically using the 2D-cylindrical, ponderomotive code INF&RNO. We also discuss the extension of these results to the nonlinear regime, where an analytical theory of the nonlinear wake phase velocity is lacking. Work supported by the Office of Science, Office of High Energy Physics, of the U.S. Department of Energy under Contract No. DE-AC02-05CH11231.

A repetitive S-band long-pulse relativistic backward-wave oscillator.

PubMed

Jin, Zhenxing; Zhang, Jun; Yang, Jianhua; Zhong, Huihuang; Qian, Baoliang; Shu, Ting; Zhang, Jiande; Zhou, Shengyue; Xu, Liurong

2011-08-01

This paper presents both numerical and experimental studies of a repetitive S-band long-pulse relativistic backward-wave oscillator. The dispersion relation curve of the main slow-wave structure is given by the numerical calculation. Experimental results show that a 1 GW microwaves with pulse duration of about 100 ns (full width of half magnitude) under 10 Hz repetitive operation mode are obtained. The microwave frequency is 3.6 GHz with the dominant mode of TM(01), and power conversion efficiency is about 20%. The single pulse energy is about 100 J. The experimental results are in good agreement with the simulation ones. By analyzing the experimental phenomenon, we obtain the conclusion that the explosive emission on the surface of the electrodynamics structure in intense radio frequency field mainly leads to the earlier unexpected termination of microwave output.

Dual physiological rate measurement instrument

NASA Technical Reports Server (NTRS)

Cooper, Tommy G. (Inventor)

1990-01-01

The object of the invention is to provide an instrument for converting a physiological pulse rate into a corresponding linear output voltage. The instrument which accurately measures the rate of an unknown rectangular pulse wave over an extended range of values comprises a phase-locked loop including a phase comparator, a filtering network, and a voltage-controlled oscillator, arranged in cascade. The phase comparator has a first input responsive to the pulse wave and a second input responsive to the output signal of the voltage-controlled oscillator. The comparator provides a signal dependent on the difference in phase and frequency between the signals appearing on the first and second inputs. A high-input impedance amplifier accepts an output from the filtering network and provides an amplified output DC signal to a utilization device for providing a measurement of the rate of the pulse wave.

Time-resolved microscopy reveals the driving mechanism of particle formation during ultrashort pulse laser ablation of dentin-like ivory

NASA Astrophysics Data System (ADS)

Domke, Matthias; Gavrilova, Anna; Rapp, Stephan; Frentzen, Matthias; Meister, Joerg; Huber, Heinz P.

2015-07-01

In dental health care, the application of ultrashort laser pulses enables dental tissue ablation free from thermal side effects, such as melting and cracking. However, these laser types create undesired micro- and nanoparticles, which might cause a health risk for the patient or surgeon. The aim of this study was to investigate the driving mechanisms of micro- and nanoparticle formation during ultrashort pulse laser ablation of dental tissue. Time-resolved microscopy was chosen to observe the ablation dynamics of mammoth ivory after irradiation with 660 fs laser pulses. The results suggest that nanoparticles might arise in the excited region. The thermal expansion of the excited material induces high pressure in the surrounding bulk tissue, generating a pressure wave. The rarefaction wave behind this pressure wave causes spallation, leading to ejection of microparticles.

Ultrahigh-resolution spectroscopy with atomic or molecular dark resonances: Exact steady-state line shapes and asymptotic profiles in the adiabatic pulsed regime

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zanon-Willette, Thomas; Clercq, Emeric de; Arimondo, Ennio

2011-12-15

Exact and asymptotic line shape expressions are derived from the semiclassical density matrix representation describing a set of closed three-level {Lambda} atomic or molecular states including decoherences, relaxation rates, and light shifts. An accurate analysis of the exact steady-state dark-resonance profile describing the Autler-Townes doublet, the electromagnetically induced transparency or coherent population trapping resonance, and the Fano-Feshbach line shape leads to the linewidth expression of the two-photon Raman transition and frequency shifts associated to the clock transition. From an adiabatic analysis of the dynamical optical Bloch equations in the weak field limit, a pumping time required to efficiently trap amore » large number of atoms into a coherent superposition of long-lived states is established. For a highly asymmetrical configuration with different decay channels, a strong two-photon resonance based on a lower states population inversion is established when the driving continuous-wave laser fields are greatly unbalanced. When time separated resonant two-photon pulses are applied in the adiabatic pulsed regime for atomic or molecular clock engineering, where the first pulse is long enough to reach a coherent steady-state preparation and the second pulse is very short to avoid repumping into a new dark state, dark-resonance fringes mixing continuous-wave line shape properties and coherent Ramsey oscillations are created. Those fringes allow interrogation schemes bypassing the power broadening effect. Frequency shifts affecting the central clock fringe computed from asymptotic profiles and related to the Raman decoherence process exhibit nonlinear shapes with the three-level observable used for quantum measurement. We point out that different observables experience different shifts on the lower-state clock transition.« less

Pressure wave charged repetitively pulsed gas laser

DOEpatents

Kulkarny, Vijay A.

1982-01-01

A repetitively pulsed gas laser in which a system of mechanical shutters bracketing the laser cavity manipulate pressure waves resulting from residual energy in the cavity gas following a lasing event so as to draw fresh gas into the cavity and effectively pump spent gas in a dynamic closed loop.

Generation of ultrasound in materials using continuous-wave lasers.

PubMed

Caron, James N; DiComo, Gregory P; Nikitin, Sergei

2012-03-01

Generating and detecting ultrasound is a standard method of nondestructive evaluation of materials. Pulsed lasers are used to generate ultrasound remotely in situations that prohibit the use of contact transducers. The scanning rate is limited by the repetition rates of the pulsed lasers, ranging between 10 and 100 Hz for lasers with sufficient pulse widths and energies. Alternately, a high-power continuous-wave laser can be scanned across the surface, creating an ultrasonic wavefront. Since generation is continuous, the scanning rate can be as much as 4 orders of magnitude higher than with pulsed lasers. This paper introduces the concept, comparing the theoretical scanning speed with generation by pulsed laser. © 2012 Optical Society of America

Optical trapping of nanoparticles by ultrashort laser pulses.

PubMed

Usman, Anwar; Chiang, Wei-Yi; Masuhara, Hiroshi

2013-01-01

Optical trapping with continuous-wave lasers has been a fascinating field in the optical manipulation. It has become a powerful tool for manipulating micrometer-sized objects, and has been widely applied in physics, chemistry, biology, material, and colloidal science. Replacing the continuous-wave- with pulsed-mode laser in optical trapping has already revealed some novel phenomena, including the stable trap, modifiable trapping positions, and controllable directional optical ejections of particles in nanometer scales. Due to two distinctive features; impulsive peak powers and relaxation time between consecutive pulses, the optical trapping with the laser pulses has been demonstrated to have some advantages over conventional continuous-wave lasers, particularly when the particles are within Rayleigh approximation. This would open unprecedented opportunities in both fundamental science and application. This Review summarizes recent advances in the optical trapping with laser pulses and discusses the electromagnetic formulations and physical interpretations of the new phenomena. Its aim is rather to show how beautiful and promising this field will be, and to encourage the in-depth study of this field.

Transmission loss measurement of acoustic material using time-domain pulse-separation method (L).

PubMed

Sun, Liang; Hou, Hong

2011-04-01

An alternative method for measuring the normal incidence sound transmission loss (nSTL) is presented in this paper based on the time-domain separation of so-called Butterworth pulse with a short-duration time about 1 ms in a standing wave tube. During the generation process of the pulse, inverse filter principle was adopted to compensate the loudspeaker response, besides this, the effect of the characteristics of tube termination can be eliminated through the generation process of the pulse so as to obtain a single plane pulse wave in the standing wave tube which makes the nSTL measurement very simple. A polyurethane foam material with low transmission loss and a kind of rubber material with relatively high transmission loss are used to verify the proposed method. When compared with the traditional two-load method, a relatively good agreement between these two methods can be observed. The main error of this method results from the measuring accuracy of the amplitude of transmission coefficient.

Energy, momentum, and angular momentum of sound pulses.

PubMed

Lekner, John

2017-12-01

Pulse solutions of the wave equation can be expressed as superpositions of scalar monochromatic beam wavefunctions (solutions of the Helmholtz equation). This formulation leads to causal (unidirectional) propagation, in contrast to all currently known closed-form solutions of the wave equation. Application is made to the evaluation of the energy, momentum, and angular momentum of acoustic pulses, as integrals over the beam and pulse weight functions. Equivalence is established between integration over space of the energy, momentum, and angular momentum densities, and integration over the wavevector weight function. The inequality linking the total energy and the total momentum is made explicit in terms of the weight function formulation. It is shown that a general pulse can be viewed as a superposition of phonons, each with energy ℏck, z component of momentum ℏq, and z component of angular momentum ℏm. A closed-form solution of the wave equation is found, which is localized and causal, and its energy and momentum are evaluated explicitly.

Traveling waves and conservation laws for highly nonlinear wave equations modeling Hertz chains

NASA Astrophysics Data System (ADS)

Przedborski, Michelle; Anco, Stephen C.

2017-09-01

A highly nonlinear, fourth-order wave equation that models the continuum theory of long wavelength pulses in weakly compressed, homogeneous, discrete chains with a general power-law contact interaction is studied. For this wave equation, all solitary wave solutions and all nonlinear periodic wave solutions, along with all conservation laws, are derived. The solutions are explicitly parameterized in terms of the asymptotic value of the wave amplitude in the case of solitary waves and the peak of the wave amplitude in the case of nonlinear periodic waves. All cases in which the solution expressions can be stated in an explicit analytic form using elementary functions are worked out. In these cases, explicit expressions for the total energy and total momentum for all solutions are obtained as well. The derivation of the solutions uses the conservation laws combined with an energy analysis argument to reduce the wave equation directly to a separable first-order differential equation that determines the wave amplitude in terms of the traveling wave variable. This method can be applied more generally to other highly nonlinear wave equations.

Experimental Test of Coupled Wave Model of Large Coils

DTIC Science & Technology

1985-06-01

46556 Abstract: Recent data from Time Domain Pulse Reflectometry experiments on a three turn coil in the form of a race track corroborate the...Domain Pulse Reflectometry experiments on a three turn coil in the form of a race track corroborate the theory of coupled wave model for large coils...Gabriel, "Coupled Wave Model for Large Magnet Coils", NASA Contractor Report 3332, National Aeronautics and Space Administration, Washington, DC

Polarization control of terahertz waves generated by circularly polarized few-cycle laser pulses

NASA Astrophysics Data System (ADS)

Song, Liwei; Bai, Ya; Xu, Rongjie; Li, Chuang; Liu, Peng; Li, Ruxin; Xu, Zhizhan

2013-12-01

We demonstrate the generation and control of elliptically polarized terahertz (THz) waves from air plasma produced by circularly polarized few-cycle laser pulses. Experimental and calculated results reveal that electric field asymmetry in rotating directions of the circularly polarized few-cycle laser pulses produces the enhanced broadband transient currents, and the phase difference of perpendicular laser field components is partially inherited in the generation process of THz emission. The ellipticity of the THz emission and its major axis direction are all-optically controlled by the duration and carrier-envelope phase of the laser pulses.

Carrier-envelope phase control of carrier-wave Rabi flopping in asymmetric semiparabolic quantum well.

PubMed

Zhang, Chaojin; Song, Xiaohong; Yang, Weifeng; Xu, Zhizhan

2008-02-04

We investigate the carrier-wave Rabi flopping effects in an asymmetric semiparabolic semiconductor quantum well (QW) with few-cycle pulse. It is found that higher spectral components of few-cycle ultrashort pulses in the semiparabolic QW depend crucially on the carrier-envelope phase (CEP) of the few-cycle ultrashort pulses: continuum and distinct peaks can be achieved by controlling the CEP. Our results demonstrate that by adjusting the CEP of few-cycle ultrashort pulses, the intersubband dynamics in the asymmetric semiparabolic QW can be controlled in an ultrashort timescale with moderate laser intensity.

Comparison of pulse wave velocity and pulse pressure amplification in association with target organ damage in community-dwelling elderly: The Northern Shanghai Study.

PubMed

Bai, Bin; Teliewubai, Jiadela; Lu, Yuyan; Yu, Shikai; Xiong, Jing; Chi, Chen; Zhou, Yiwu; Ji, Hongwei; Fan, Ximin; Blacher, Jacques; Li, Jue; Zhang, Yi; Xu, Yawei

2018-05-01

This study aimed to investigate the discrepancy between pulse wave velocity (PWV) and pulse pressure amplification (PPA) in association with hypertensive target organ damage (TOD) in the elderly. From June 2014 to August 2015, 1599 participants aged >65 years old from communities located in northern Shanghai were recruited. Carotid-femoral pulse wave velocity (cfPWV), peripheral blood pressure (BP), central BP and other TOD indicators, including the ratio of the early ventricular filling velocity (E) to the peak velocity of the tissue Doppler velocity of septal mitral annulus (E/Ea), left ventricular mass index (LVMI), carotid intima-medium thickness (CIMT), estimated glomerular filtration rate (eGFR), and urinary albumin-creatinine ratio (ACR), were determined for each participant. PPA was defined as the peripheral-to-central pulse pressure ratio. In multivariable linear regression analysis, cfPWV was significantly associated with CIMT (β = 12.83 ± 4.28 μm per SD; P = 0.003) and eGFR (β = -1.85 ± 0.69 ml/min/1.73 m 2 per SD; P = 0.007), whereas PPA was significantly associated with E/Ea (β = -0.25 ± 0.10 per SD; P = 0.01) and LVMI (β = -3.00 ± 0.78 g/m 2 per SD; P < 0.001). Similarly, in multivariable logistic regression analysis, cfPWV was significantly associated with arterial plaque (odds ratio [OR], 1.21 [95% confidence interval [CI], 1.05-1.39]; P = 0.007), peripheral artery disease (OR, 1.22 [95% CI, 1.06-1.42]; P = 0.007), chronic kidney diseases (OR, 1.24 [95% CI, 1.01-1.54]; P = 0.04) and microalbuminuria (OR, 1.21 [95% CI, 1.07-1.37]; P = 0.002), while PPA was tightly associated with left ventricular hypertrophy (OR, 0.85 [95% CI, 0.72-0.99]; P = 0.04) and diastolic dysfunction (OR, 0.78 [95% CI, 0.64-0.96]; P = 0.02). In conclusion, cfPWV is a vessel-related and renal-related biomarker, while PPA is a cardiac-related biomarker in community-based elderly.

Acute changes in arterial stiffness following exercise in people with metabolic syndrome.

PubMed

Radhakrishnan, Jeyasundar; Swaminathan, Narasimman; Pereira, Natasha M; Henderson, Keiran; Brodie, David A

This study aims to examine the changes in arterial stiffness immediately following sub-maximal exercise in people with metabolic syndrome. Ninety-four adult participants (19-80 years) with metabolic syndrome gave written consent and were measured for arterial stiffness using a SphygmoCor (SCOR-PVx, Version 8.0, Atcor Medical Private Ltd, USA) immediately before and within 5-10min after an incremental shuttle walk test. The arterial stiffness measures used were pulse wave velocity (PWV), aortic pulse pressure (PP), augmentation pressure, augmentation index (AI), subendocardial viability ratio (SEVR) and ejection duration (ED). There was a significant increase (p<0.05) in most of the arterial stiffness variables following exercise. Exercise capacity had a strong inverse correlation with arterial stiffness and age (p<0.01). Age influences arterial stiffness. Exercise capacity is inversely related to arterial stiffness and age in people with metabolic syndrome. Exercise induced changes in arterial stiffness measured using pulse wave analysis is an important tool that provides further evidence in studying cardiovascular risk in metabolic syndrome. Copyright © 2016 Diabetes India. Published by Elsevier Ltd. All rights reserved.

Nonlinear Brillouin amplification of finite-duration seeds in the strong coupling regime

NASA Astrophysics Data System (ADS)

Lehmann, G.; Spatschek, K. H.

2013-07-01

Parametric plasma processes received renewed interest in the context of generating ultra-intense and ultra-short laser pulses up to the exawatt-zetawatt regime. Both Raman as well as Brillouin amplifications of seed pulses were proposed. Here, we investigate Brillouin processes in the one-dimensional (1D) backscattering geometry with the help of numerical simulations. For optimal seed amplification, Brillouin scattering is considered in the so called strong coupling (sc) regime. Special emphasis lies on the dependence of the amplification process on the finite duration of the initial seed pulses. First, the standard plane-wave instability predictions are generalized to pulse models, and the changes of initial seed pulse forms due to parametric instabilities are investigated. Three-wave-interaction results are compared to predictions by a new (kinetic) Vlasov code. The calculations are then extended to the nonlinear region with pump depletion. Generation of different seed layers is interpreted by self-similar solutions of the three-wave interaction model. Similar to Raman amplification, shadowing of the rear layers by the leading layers of the seed occurs. The shadowing is more pronounced for initially broad seed pulses. The effect is quantified for Brillouin amplification. Kinetic Vlasov simulations agree with the three-wave interaction predictions and thereby affirm the universal validity of self-similar layer formation during Brillouin seed amplification in the strong coupling regime.

Transient thermal stress wave and vibrational analyses of a thin diamond crystal for X-ray free-electron lasers under high-repetition-rate operation

DOE PAGES

Yang, Bo; Wang, Songwei; Wu, Juhao

2018-01-01

High-brightness X-ray free-electron lasers (FELs) are perceived as fourth-generation light sources providing unprecedented capabilities for frontier scientific researches in many fields. Thin crystals are important to generate coherent seeds in the self-seeding configuration, provide precise spectral measurements, and split X-ray FEL pulses, etc. In all of these applications a high-intensity X-ray FEL pulse impinges on the thin crystal and deposits a certain amount of heat load, potentially impairing the performance. In the present paper, transient thermal stress wave and vibrational analyses as well as transient thermal analysis are carried out to address the thermomechanical issues for thin diamond crystals, especiallymore » under high-repetition-rate operation of an X-ray FEL. The material properties at elevated temperatures are considered. It is shown that, for a typical FEL pulse depositing tens of microjoules energy over a spot of tens of micrometers in radius, the stress wave emission is completed on the tens of nanoseconds scale. The amount of kinetic energy converted from a FEL pulse can reach up to ~10 nJ depending on the layer thickness. Natural frequencies of a diamond plate are also computed. The potential vibrational amplitude is estimated as a function of frequency. Here, due to the decreasing heat conductivity with increasing temperature, a runaway temperature rise is predicted for high repetition rates where the temperature rises abruptly after ratcheting up to a point of trivial heat damping rate relative to heat deposition rate.« less

Transient thermal stress wave and vibrational analyses of a thin diamond crystal for X-ray free-electron lasers under high-repetition-rate operation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yang, Bo; Wang, Songwei; Wu, Juhao

High-brightness X-ray free-electron lasers (FELs) are perceived as fourth-generation light sources providing unprecedented capabilities for frontier scientific researches in many fields. Thin crystals are important to generate coherent seeds in the self-seeding configuration, provide precise spectral measurements, and split X-ray FEL pulses, etc. In all of these applications a high-intensity X-ray FEL pulse impinges on the thin crystal and deposits a certain amount of heat load, potentially impairing the performance. In the present paper, transient thermal stress wave and vibrational analyses as well as transient thermal analysis are carried out to address the thermomechanical issues for thin diamond crystals, especiallymore » under high-repetition-rate operation of an X-ray FEL. The material properties at elevated temperatures are considered. It is shown that, for a typical FEL pulse depositing tens of microjoules energy over a spot of tens of micrometers in radius, the stress wave emission is completed on the tens of nanoseconds scale. The amount of kinetic energy converted from a FEL pulse can reach up to ~10 nJ depending on the layer thickness. Natural frequencies of a diamond plate are also computed. The potential vibrational amplitude is estimated as a function of frequency. Here, due to the decreasing heat conductivity with increasing temperature, a runaway temperature rise is predicted for high repetition rates where the temperature rises abruptly after ratcheting up to a point of trivial heat damping rate relative to heat deposition rate.« less

Transient thermal stress wave and vibrational analyses of a thin diamond crystal for X-ray free-electron lasers under high-repetition-rate operation.

PubMed

Yang, Bo; Wang, Songwei; Wu, Juhao

2018-01-01

High-brightness X-ray free-electron lasers (FELs) are perceived as fourth-generation light sources providing unprecedented capabilities for frontier scientific researches in many fields. Thin crystals are important to generate coherent seeds in the self-seeding configuration, provide precise spectral measurements, and split X-ray FEL pulses, etc. In all of these applications a high-intensity X-ray FEL pulse impinges on the thin crystal and deposits a certain amount of heat load, potentially impairing the performance. In the present paper, transient thermal stress wave and vibrational analyses as well as transient thermal analysis are carried out to address the thermomechanical issues for thin diamond crystals, especially under high-repetition-rate operation of an X-ray FEL. The material properties at elevated temperatures are considered. It is shown that, for a typical FEL pulse depositing tens of microjoules energy over a spot of tens of micrometers in radius, the stress wave emission is completed on the tens of nanoseconds scale. The amount of kinetic energy converted from a FEL pulse can reach up to ∼10 nJ depending on the layer thickness. Natural frequencies of a diamond plate are also computed. The potential vibrational amplitude is estimated as a function of frequency. Due to the decreasing heat conductivity with increasing temperature, a runaway temperature rise is predicted for high repetition rates where the temperature rises abruptly after ratcheting up to a point of trivial heat damping rate relative to heat deposition rate.

Acoustic Guided Wave Testing of Pipes of Small Diameters

NASA Astrophysics Data System (ADS)

Muravev, V. V.; Muraveva, O. V.; Strizhak, V. A.; Myshkin, Y. V.

2017-10-01

Acoustic path is analyzed and main parameters of guided wave testing are substanti- ated applied to pipes of small diameters. The method is implemented using longitudinal L(0,1) and torsional T(0,1) waves based on electromagnetic-acoustic (EMA) transducers. The method of multiple reflections (MMR) combines echo-through, amplitude-shadow and time-shadow methods. Due to the effect of coherent amplification of echo-pulses from defects the sensitivity to the defects of small sizes at the signal analysis on the far reflections is increased. An oppor- tunity of detection of both local defects (dents, corrosion damages, rolling features, pitting, cracks) and defects extended along the pipe is shown.

Pulse compression favourable aperiodic infrared imaging approach for non-destructive testing and evaluation of bio-materials

NASA Astrophysics Data System (ADS)

Mulaveesala, Ravibabu; Dua, Geetika; Arora, Vanita; Siddiqui, Juned A.; Muniyappa, Amarnath

2017-05-01

In recent years, aperiodic, transient pulse compression favourable infrared imaging methodologies demonstrated as reliable, quantitative, remote characterization and evaluation techniques for testing and evaluation of various biomaterials. This present work demonstrates a pulse compression favourable aperiodic thermal wave imaging technique, frequency modulated thermal wave imaging technique for bone diagnostics, especially by considering the bone with tissue, skin and muscle over layers. In order to find the capabilities of the proposed frequency modulated thermal wave imaging technique to detect the density variations in a multi layered skin-fat-muscle-bone structure, finite element modeling and simulation studies have been carried out. Further, frequency and time domain post processing approaches have been adopted on the temporal temperature data in order to improve the detection capabilities of frequency modulated thermal wave imaging.

Data Analysis of the NOAA-GIT (National Oceanic and Atmospheric Administration-Georgia Institute of Technology) Millimeter-Wave Propagation Experiment Near Flatville, Illinois.

DTIC Science & Technology

1985-08-01

nearby Lyman-a hygrometer with another wire ther- mometer within its gap, a prop-vane anemometer, and a psychrometer for mean temperature and...0.39-Hz pulse, the psychrometer gives six commutation cycles repeated at the 25-Hz rate. A commutation cycle consists of data from the wet and dry...bulbs and two reference values, four quantities in all. The psychrometer then returns toward thermal equilibrium until the next 0.39-Hz pulse calls for

A Wearable and Highly Sensitive Graphene Strain Sensor for Precise Home-Based Pulse Wave Monitoring.

PubMed

Yang, Tingting; Jiang, Xin; Zhong, Yujia; Zhao, Xuanliang; Lin, Shuyuan; Li, Jing; Li, Xinming; Xu, Jianlong; Li, Zhihong; Zhu, Hongwei

2017-07-28

Profuse medical information about cardiovascular properties can be gathered from pulse waveforms. Therefore, it is desirable to design a smart pulse monitoring device to achieve noninvasive and real-time acquisition of cardiovascular parameters. The majority of current pulse sensors are usually bulky or insufficient in sensitivity. In this work, a graphene-based skin-like sensor is explored for pulse wave sensing with features of easy use and wearing comfort. Moreover, the adjustment of the substrate stiffness and interfacial bonding accomplish the optimal balance between sensor linearity and signal sensitivity, as well as measurement of the beat-to-beat radial arterial pulse. Compared with the existing bulky and nonportable clinical instruments, this highly sensitive and soft sensing patch not only provides primary sensor interface to human skin, but also can objectively and accurately detect the subtle pulse signal variations in a real-time fashion, such as pulse waveforms with different ages, pre- and post-exercise, thus presenting a promising solution to home-based pulse monitoring.

Pulse transit time differential measurement by fiber Bragg grating pulse recorder.

PubMed

Umesh, Sharath; Padma, Srivani; Ambastha, Shikha; Kalegowda, Anand; Asokan, Sundarrajan

2015-05-01

The present study reports a noninvasive technique for the measurement of the pulse transit time differential (PTTD) from the pulse pressure waveforms obtained at the carotid artery and radial artery using fiber Bragg grating pulse recorders (FBGPR). PTTD is defined as the time difference between the arrivals of a pulse pressure waveform at the carotid and radial arterial sites. The PTTD is investigated as an indicator of variation in the systolic blood pressure. The results are validated against blood pressure variation obtained from a Mindray Patient Monitor. Furthermore, the pulse wave velocity computed from the obtained PTTD is compared with the pulse wave velocity obtained from the color Doppler ultrasound system and is found to be in good agreement. The major advantage of the PTTD measurement via FBGPRs is that the data acquisition system employed can simultaneously acquire pulse pressure waveforms from both FBGPRs placed at carotid and radial arterial sites with a single time scale, which eliminates time synchronization complexity.

Sound Beams with Shockwave Pulses

NASA Astrophysics Data System (ADS)

Enflo, B. O.

2000-11-01

The beam equation for a sound beam in a diffusive medium, called the Khokhlov-Zabolotskaya-Kuznetsov (KZK) equation, has a class of solutions, which are power series in the transverse variable with the terms given by a solution of a generalized Burgers’ equation. A free parameter in this generalized Burgers’ equation can be chosen so that the equation describes an N-wave which does not decay. If the beam source has the form of a spherical cap, then a beam with a preserved shock can be prepared. This is done by satisfying an inequality containing the spherical radius, the N-wave pulse duration, the N-wave pulse amplitude, and the sound velocity in the fluid.

Traversal of electromagnetic pulses through dispersive media with negative refractive index

NASA Astrophysics Data System (ADS)

Nanda, L.; Ramakrishna, S. A.

2017-05-01

We investigate the traversal of electromagnetic pulses through dispersive media with negative refractive index in such a way that no resonant effects come into play. It has been verified that for evanescent waves, the definitions of the group delay and the reshaping delay times get interchanged in comparison to the propagating waves. We show that for a negative refractive index medium (NRM) with ɛ(ω)=μ(ω), the reshaping delay time identically vanishes for propagating waves. The total delay time in NRM is otherwise contributed by both the group and the reshaping delay times, whereas for the case of broadband pulses in NRM the total delay time is always subluminal.

Response functions of free mass gravitational wave antennas

NASA Technical Reports Server (NTRS)

Estabrook, F. B.

1985-01-01

The work of Gursel, Linsay, Spero, Saulson, Whitcomb and Weiss (1984) on the response of a free-mass interferometric antenna is extended. Starting from first principles, the earlier work derived the response of a 2-arm gravitational wave antenna to plane polarized gravitational waves. Equivalent formulas (generalized slightly to allow for arbitrary elliptical polarization) are obtained by a simple differencing of the '3-pulse' Doppler response functions of two 1-arm antennas. A '4-pulse' response function is found, with quite complicated angular dependences for arbitrary incident polarization. The differencing method can as readily be used to write exact response functions ('3n+1 pulse') for antennas having multiple passes or more arms.

Process for laser machining and surface treatment

DOEpatents

Neil, George R.; Shinn, Michelle D.

2004-10-26

An improved method and apparatus increasing the accuracy and reducing the time required to machine materials, surface treat materials, and allow better control of defects such as particulates in pulsed laser deposition. The speed and quality of machining is improved by combining an ultrashort pulsed laser at high average power with a continuous wave laser. The ultrashort pulsed laser provides an initial ultrashort pulse, on the order of several hundred femtoseconds, to stimulate an electron avalanche in the target material. Coincident with the ultrashort pulse or shortly after it, a pulse from a continuous wave laser is applied to the target. The micromachining method and apparatus creates an initial ultrashort laser pulse to ignite the ablation followed by a longer laser pulse to sustain and enlarge on the ablation effect launched in the initial pulse. The pulse pairs are repeated at a high pulse repetition frequency and as often as desired to produce the desired micromachining effect. The micromachining method enables a lower threshold for ablation, provides more deterministic damage, minimizes the heat affected zone, minimizes cracking or melting, and reduces the time involved to create the desired machining effect.

Serum uric Acid level and diverse impacts on regional arterial stiffness and wave reflection.

PubMed

Bian, Suyan; Guo, Hongyang; Ye, Ping; Luo, Leiming; Wu, Hongmei; Xiao, Wenkai

2012-01-01

Both increased arterial stiffness and hyperuricaemia are associated with elevated cardiovascular risks. Little is known about the relations of serum uric acid (UA) level to regional arterial stiffness and wave reflection. The aim of the study was to investigate the gender-specific association of serum UA and indices of arterial function in a community-based investigation in China. Cross-sectional data from 2374 adults (mean age 58.24 years) who underwent routine laboratory tests, regional pulse wave velocity (PWV) and pulse wave analysis measurements were analyzed in a gender-specific manner. None of the participants had atherosclerotic cardiovascular disease, chronic renal failure, systemic inflammatory disease, gout, or were under treatment which would affect serum UA level. Men had higher serum UA level than women. Subjects with hyperuricaemia had significantly higher carotid-ankle PWV in both genders (P< 0.05), and the carotid-femoral PWV (PWVc-f) was higher in women (P< 0.001) while the augmentation index was marginally lower in men (P = 0.049). Multiple regression analysis showed that serum UA was an independent determinant only for PWVc-f in women (β = 0.104, P = 0.027) when adjusted for atherogenic confounders. No other independent relationship was found between UA level and other surrogates of arterial stiffness. Serum UA levels are associated with alterations in systemic arterial stiffness that differ in men and women. Women might be more susceptible to large vascular damage associated with hyperuricaemia.

Post Hoc Analysis of Passive Cavitation Imaging for Classification of Histotripsy-Induced Liquefaction in Vitro.

PubMed

Bader, Kenneth B; Haworth, Kevin J; Maxwell, Adam D; Holland, Christy K

2018-01-01

Histotripsy utilizes focused ultrasound to generate bubble clouds for transcutaneous tissue liquefaction. Bubble activity maps are under development to provide image guidance and monitor treatment progress. The aim of this paper was to investigate the feasibility of using plane wave B-mode and passive cavitation images to be used as binary classifiers of histotripsy-induced liquefaction. Prostate tissue phantoms were exposed to histotripsy pulses over a range of pulse durations (5- ) and peak negative pressures (12-23 MPa). Acoustic emissions were recorded during the insonation and beamformed to form passive cavitation images. Plane wave B-mode images were acquired following the insonation to detect the hyperechoic bubble cloud. Phantom samples were sectioned and stained to delineate the liquefaction zone. Correlation between passive cavitation and plane wave B-mode images and the liquefaction zone was assessed using receiver operating characteristic (ROC) curve analysis. Liquefaction of the phantom was observed for all the insonation conditions. The area under the ROC (0.94 versus 0.82), accuracy (0.90 versus 0.83), and sensitivity (0.81 versus 0.49) was greater for passive cavitation images relative to B-mode images ( ) along the azimuth of the liquefaction zone. The specificity was greater than 0.9 for both imaging modalities. These results demonstrate a stronger correlation between histotripsy-induced liquefaction and passive cavitation imaging compared with the plane wave B-mode imaging, albeit with limited passive cavitation image range resolution.

Quantum phase amplification for temporal pulse shaping and super-resolution in remote sensing

NASA Astrophysics Data System (ADS)

Yin, Yanchun

The use of nonlinear optical interactions to perform nonclassical transformations of electromagnetic field is an area of considerable interest. Quantum phase amplification (QPA) has been previously proposed as a method to perform nonclassical manipulation of coherent light, which can be experimentally realized by use of nonlinear optical mixing processes, of which phase-sensitive three-wave mixing (PSTWM) is one convenient choice. QPA occurs when PSTWM is operated in the photon number deamplification mode, i.e., when the energy is coherently transferred among the low-frequency signal and idler waves and the high-frequency pump wave. The final state is nonclassical, with the field amplitude squeezed and the phase anti-squeezed. In the temporal domain, the use of QPA has been studied to facilitate nonlinear pulse shaping. This novel method directly shapes the temporal electric field amplitude and phase using the PSTWM in a degenerate and collinear configuration, which has been analyzed using a numerical model. Several representative pulse shaping capabilities of this technique have been identified, which can augment the performance of common passive pulse shaping methods operating in the Fourier domain. The analysis indicates that a simple quadratic variation of temporal phase facilitates pulse compression and self-steepening, with features significantly shorter than the original transform-limited pulse. Thus, PSTWM can act as a direct pulse compressor based on the combined effects of phase amplification and group velocity mismatch, even without the subsequent linear phase compensation. Furthermore, it is shown numerically that pulse doublets and pulse trains can be produced at the pump frequency by utilizing the residual linear phase of the signal. Such pulse shaping capabilities are found to be within reach of this technique in common nonlinear optical crystals pumped by pulses available from compact femtosecond chirped-pulse amplification laser systems. The use of QPA in the spatial domain has also been studied as a method to enhance the spatial resolution of imaging systems. A detailed model has been developed for achieving both super-resolution and detection of phase-amplified light. The imaging resolution problem considered here is treated as a binary hypotheses testing problem. Resolution enhancement is achieved by magnification of the angular separation of two targets in the sub-Rayleigh regime. The detection model includes optimization of detector segmentation, detector noise, and detection in both the spatial and the spatial frequency domain, which provide strategies for the optimization of the signal-to-noise ratio that take advantage of both the change of the field distribution and the change of energy of the signal in the QPA process. Proof-of-principle experiments have been conducted in the spatial domain. For the first time, beam angular amplification has been demonstrated, and the experimental result is in good agreement with simulations. The experimental demonstration has been achieved by observing the correlation of amplitude and angular phase in the phase-sensitive three-wave mixing process using ultrashort laser pulses and utilizing a type I three-wave mixing process. Several diagnostics have been developed and employed in the experimental measurements, including the near-field diagnostic, the far-field diagnostic, and the interferometry diagnostic. They have all been used to confirm the existence and study the properties of the QPA process on a shot-to-shot basis. Specifically, amplitude was measured in the near-field diagnostic, while the angular phase was indirectly measured in the far-field diagnostic by determining the position of the beam centroid. Interferometric measurements have been found to be of insufficient accuracy for this measurement in the way they were implemented. The demonstration of beam angular amplification by use of QPA lays the foundation for future integrated demonstration of imaging resolution enhancement, while the results of the modeling in the time domain open opportunities for development of flexible pulse shaping benefitting a variety of ultrafast applications.

[Comprehensive testing system for cardiorespiratory interaction research].

PubMed

Zhang, Zhengbo; Wang, Buqing; Wang, Weidong; Zheng, Jiewen; Liu, Hongyun; Li, Kaiyuan; Sun, Congcong; Wang, Guojing

2013-04-01

To investigate the modulation effects of breathing movement on cardiovascular system and to study the physiological coupling relationship between respiration and cardiovascular system, we designed a comprehensive testing system for cardiorespiratory interaction research. This system, comprising three parts, i. e. physiological signal conditioning unit, data acquisition and USB medical isolation unit, and a PC based program, can acquire multiple physiological data such as respiratory flow, rib cage and abdomen movement, electrocardiograph, artery pulse wave, cardiac sounds, skin temperature, and electromyography simultaneously under certain experimental protocols. Furthermore this system can be used in research on short-term cardiovascular variability by paced breathing. Preliminary experiments showed that this system could accurately record rib cage and abdomen movement under very low breathing rate, using respiratory inductive plethysmography to acquire respiration signal in direct-current coupling mode. After calibration, this system can be used to estimate ventilation non-intrusively and correctly. The PC based program can generate audio and visual biofeedback signal, and guide the volunteers to perform a slow and regular breathing. An experiment on healthy volunteers showed that this system was able to guide the volunteers to do slow breathing effectively and simultaneously record multiple physiological data during the experiments. Signal processing techniques were used for off-line data analysis, such as non-invasive ventilation calibration, QRS complex wave detection, and respiratory sinus arrhythmia and pulse wave transit time calculation. The experiment result showed that the modulation effect on RR interval, respiratory sinus arrhythmia (RSA), pulse wave transit time (PWTT) by respiration would get stronger with the going of the slow and regular breathing.

The association between pulse wave velocity and cognitive function: the Sydney Memory and Ageing Study.

PubMed

Singer, Joel; Trollor, Julian N; Crawford, John; O'Rourke, Michael F; Baune, Bernhard T; Brodaty, Henry; Samaras, Katherine; Kochan, Nicole A; Campbell, Lesley; Sachdev, Perminder S; Smith, Evelyn

2013-01-01

Pulse wave velocity (PWV) is a measure of arterial stiffness and its increase with ageing has been associated with damage to cerebral microvessels and cognitive impairment. This study examined the relationship between carotid-femoral PWV and specific domains of cognitive function in a non-demented elderly sample. Data were drawn from the Sydney Memory and Ageing Study, a cohort study of non-demented community-dwelling individuals aged 70-90 years, assessed in successive waves two years apart. In Wave 2, PWV and cognitive function were measured in 319 participants. Linear regression was used to analyse the cross-sectional relationship between arterial stiffness and cognitive function in the whole sample, and separately for men and women. Analysis of covariance was used to assess potential differences in cognition between subjects with PWV measurements in the top and bottom tertiles of the cohort. Covariates were age, education, body mass index, pulse rate, systolic blood pressure, cholesterol, depression, alcohol, smoking, hormone replacement therapy, apolipoprotein E ε4 genotype, use of anti-hypertensive medications, history of stroke, transient ischemic attack, myocardial infarction, angina, diabetes, and also sex for the whole sample analyses. There was no association between PWV and cognition after Bonferroni correction for multiple testing. When examining this association for males and females separately, an association was found in males, with higher PWV being associated with lower global cognition and memory, however, a significant difference between PWV and cognition between males and females was not found. A higher level of PWV was not associated with lower cognitive function in the whole sample.

Cross-Shore Exchange on Natural Beaches

DTIC Science & Technology

2014-09-01

87   Figure 2.   Wave conditions measured by the ADCP in 13 m water depth of (a) root- mean-square wave height Hrms...horizontal velocity, Umean, measured in the reference level, ∑Tsig,pulse T3−hour ∑Tsig,pulse T3−hour xi (e) local water depth, h, and (f) local root...mean-square wave height normalized by the local water depth, Hrms/h, measured by ADCPin (blue) and ADCPout (red) during the 3HRLTs. Colored lines

Method for exciting inductive-resistive loads with high and controllable direct current

DOEpatents

Hill, Jr., Homer M.

1976-01-01

Apparatus and method for transmitting dc power to a load circuit by applying a dc voltage from a standard waveform synthesizer to duration modulate a bipolar rectangular wave generator. As the amplitude of the dc voltage increases, the widths of the rectangular wave generator output pulses increase, and as the amplitude of the dc voltage decreases, the widths of the rectangular wave generator output pulses decrease. Thus, the waveform synthesizer selectively changes the durations of the rectangular wave generator bipolar output pulses so as to produce a rectangular wave ac carrier that is duration modulated in accordance with and in direct proportion to the voltage amplitude from the synthesizer. Thereupon, by transferring the carrier to the load circuit through an amplifier and a rectifier, the load current also corresponds directly to the voltage amplitude from the synthesizer. To this end, the rectified wave at less than 100% duty factor, amounts to a doubled frequency direct voltage pulse train for applying a direct current to the load, while the current ripple is minimized by a high L/R in the load circuit. In one embodiment, a power transmitting power amplifier means having a dc power supply is matched to the load circuit through a transformer for current magnification without sacrificing load current duration capability, while negative voltage and current feedback are provided in order to insure good output fidelity.

Propulsion system ignition overpressure for the Space Shuttle

NASA Technical Reports Server (NTRS)

Ryan, R. S.; Jones, J. H.; Guest, S. H.; Struck, H. G.; Rheinfurth, M. H.; Verferaime, V. S.

1981-01-01

Liquid and solid rocket motor propulsion systems create an overpressure wave during ignition, caused by the accelerating gas particles pushing against or displacing the air contained in the launch pad or launch facility and by the afterburning of the fuel-rich gases. This wave behaves as a blast or shock wave characterized by a positive triangular-shaped first pulse and a negative half-sine wave second pulse. The pulse travels up the space vehicle and has the potential of either overloading individual elements or exciting overall vehicle dynamics. The latter effect results from the phasing difference of the wave from one side of the vehicle to the other. This overpressure phasing, or delta P environment, because of its frequency content as well as amplitude, becomes a design driver for certain panels (e.g., thermal shields) and payloads for the Space Shuttle. The history of overpressure effects on the Space Shuttle, the basic overpressure phenomenon, Space Shuttle overpressure environment, scale model overpressure testing, and techniques for suppressing the overpressure environments are considered.

Areal Mass Oscillations in Planar Targets Due to Feedout: Theory and Simulations.

NASA Astrophysics Data System (ADS)

Velikovich, A. L.; Schmitt, A. J.; Karasik, M.; Obenschain, S. P.; Serlin, V.; Pawley, C. J.; Gardner, J. H.; Aglitskiy, Y.; Metzler, N.

2001-10-01

When a planar shock wave breaks out at a rippled rear surface of a laser-driven target, the lateral pressure gradient in a rippled rarefaction wave propagating back to the front surface causes a lateral mass redistribution that reverses the phase of mass variation. If the driving laser pulse has no foot, then the RT growth, starting when the rarefaction wave reaches the front surface, causes the second phase reversal of mass variation, and continues at the initial phase, as consistently observed in feedout experiments on Nike. A foot of the laser pulse can cause an early phase reversal of mass variation, making the strong shock wave driven by the main pulse interact with a density variation in a rippled rarefaction wave rather than with static rear surface ripples. Theory and simulations predict that this interaction can make the phase of mass variation reverse one or three times. Then the phase of the RT growing mode would be opposite to that of the initial mass variation.

Numerical Study of Wave Propagation in a Non-Uniform Flow

NASA Technical Reports Server (NTRS)

Povitsky, Alex; Bushnell, Dennis M. (Technical Monitor)

2000-01-01

The propagation of acoustic waves originating from cylindrical and spherical pulses, in a non-uniform mean flow, and in the presence of a reflecting wall is investigated by Hardin and Pope approach using compact approximation of spatial derivatives. The 2-D and 3-D stagnation flows and a flow around a cylinder are taken as prototypes of real world flows with strong gradients of mean pressure and velocity. The intensity and directivity of acoustic wave patterns appear to be quite different from the benchmark solutions obtained in a static environment for the same geometry. The physical reasons for amplification and weakening of sound are discussed in terms of dynamics of wave profile and redistribution of acoustic energy and its potential and kinetic components. For an acoustic wave in the flow around a cylinder, the observed mean acoustic pressure is approximately doubled (upstream pulse position) and halved (downstream pulse position) in comparison with the sound propagation in static ambient conditions.

Effects of Acupuncture Stimulation on the Radial artery’s Pressure Pulse Wave in Healthy Young Participants: Protocol for a prospective, single-Arm, Exploratory, Clinical Study

PubMed Central

Shin, Jae-Young; Lee, Jun-Hwan; Ku, Boncho; Bae, Jang Han; un, Min-Ho; Kim, Jaeuk U.; Kim, Tae-Hun

2016-01-01

Introduction: This study aims to investigate the effects of acupuncture stimulation on the radial artery’s pressure pulse wave, along with various hemodynamic parameters, and to explore the possible underlying mechanism of pulse diagnosis in healthy participants in their twenties. Methods and analysis: This study is a prospective, single-arm, exploratory clinical study. A total of 25 healthy participants, without regard to gender, in their twenties will be recruited by physicians. Written informed consent will be obtained from all participants. The participants will receive acupuncture once at ST36 on both sides. The radial arterial pulse waves will be measured on the left arm of the subjects by using an applicable pulse tonometric device (KIOM-PAS). On the right arm (appearing twice), electrocardiogram (ECG), photoplethysmogram (PPG), respiration and cardiac output (CO) signals, will be measured using a physiological data acquisition system (Biopac module), while the velocity of blood flow, and the diameter and the depth of the blood vessel will be measured using an ultrasonogram machine on the right arm (appearing twice). All measurements will be conducted before, during, and after acupuncture. The primary outcome will be the spectral energy at high frequencies above 10 Hz (SE10-30Hz) calculated from the KIOM-PAS device signal. Secondary outcomes will be various variables obtained from the KIOM-PAS device, ECG, PPG, impedance cardiography modules, and an ultrasonogram machine. Discussion: The results of this trial will provide information regarding the physiological and the hemodynamic mechanisms underlying acupuncture stimulation and clinical evidence for the influence of acupuncture on the pressure pulse wave in the radial artery. Ethics and dissemination: This study was approved by the Institutional Review Board (IRB) of Kyung Hee University’s Oriental Medical Center, Seoul, Korea (KOMCIRB-150818-HR-030). The study findings will be published in peer-reviewed journals and presented at national and international conferences. Trial registration number: This trial was registered with the Clinical Research Information Service (CRIS) at the Korea National Institute of Health (NIH), Republic of Korea (KCT0001663), which is a registry in the World Health Organization’s (WHO’s) Registry Network. PMID:27695628

Generalized dispersive wave emission in nonlinear fiber optics.

PubMed

Webb, K E; Xu, Y Q; Erkintalo, M; Murdoch, S G

2013-01-15

We show that the emission of dispersive waves in nonlinear fiber optics is not limited to soliton-like pulses propagating in the anomalous dispersion regime. We demonstrate, both numerically and experimentally, that pulses propagating in the normal dispersion regime can excite resonant dispersive radiation across the zero-dispersion wavelength into the anomalous regime.

Cerebrovascular Damage Mediates Relations Between Aortic Stiffness and Memory.

PubMed

Cooper, Leroy L; Woodard, Todd; Sigurdsson, Sigurdur; van Buchem, Mark A; Torjesen, Alyssa A; Inker, Lesley A; Aspelund, Thor; Eiriksdottir, Gudny; Harris, Tamara B; Gudnason, Vilmundur; Launer, Lenore J; Mitchell, Gary F

2016-01-01

Aortic stiffness is associated with cognitive decline. Here, we examined the association between carotid-femoral pulse wave velocity and cognitive function and investigated whether cerebrovascular remodeling and parenchymal small vessel disease damage mediate the relation. Analyses were based on 1820 (60% women) participants in the Age, Gene/Environment Susceptibility-Reykjavik Study. Multivariable linear regression models adjusted for vascular and demographic confounders showed that higher carotid-femoral pulse wave velocity was related to lower memory score (standardized β: -0.071±0.023; P=0.002). Cerebrovascular resistance and white matter hyperintensities were each associated with carotid-femoral pulse wave velocity and memory (P<0.05). Together, cerebrovascular resistance and white matter hyperintensities (total indirect effect: -0.029; 95% CI, -0.043 to -0.017) attenuated the direct relation between carotid-femoral pulse wave velocity and memory (direct effect: -0.042; 95% CI, -0.087 to 0.003; P=0.07) and explained ≈41% of the observed effect. Our results suggest that in older adults, associations between aortic stiffness and memory are mediated by pathways that include cerebral microvascular remodeling and microvascular parenchymal damage. © 2015 American Heart Association, Inc.

Visualisation of an nsPEF induced calcium wave using the genetically encoded calcium indicator GCaMP in U87 human glioblastoma cells.

PubMed

Carr, Lynn; Bardet, Sylvia M; Arnaud-Cormos, Delia; Leveque, Philippe; O'Connor, Rodney P

2018-02-01

Cytosolic, synthetic chemical calcium indicators are typically used to visualise the rapid increase in intracellular calcium ion concentration that follows nanosecond pulsed electric field (nsPEF) application. This study looks at the application of genetically encoded calcium indicators (GECIs) to investigate the spatiotemporal nature of nsPEF-induced calcium signals using fluorescent live cell imaging. Calcium responses to 44kV/cm, 10ns pulses were observed in U87-MG cells expressing either a plasma membrane targeted GECI (GCaMP5-G), or one cytosolically expressed (GCaMP6-S), and compared to the response of cells loaded with cytosolic or plasma membrane targeted chemical calcium indicators. Application of 100 pulses, to cells containing plasma membrane targeted indicators, revealed a wave of calcium across the cell initiating at the cathode side. A similar spatial wave was not observed with cytosolic indicators with mobile calcium buffering properties. The speed of the wave was related to pulse application frequency and it was not propagated by calcium induced calcium release. Copyright © 2017 Elsevier B.V. All rights reserved.

Interaction of excitable waves emitted from two defects by pulsed electric fields

NASA Astrophysics Data System (ADS)

Chen, Jiang-Xing; Zhang, Han; Qiao, Li-Yan; Liang, Hong; Sun, Wei-Gang

2018-01-01

In response to a pulsed electric field, spatial distributed heterogeneities in excitable media can serve as nucleation sites for the generation of intramural electrical waves, a phenomenon called as ;wave emission from heterogeneities; (WEH effect). Heterogeneities in cardiac tissue strongly influence each other in the WEH effect. We study the WEH effect in a medium possessing two defects. The role of two defects and their interaction by pulsed DC electric fields (DEF) and rotating electric fields (REF) are investigated. The direction of the applied electric field plays a major role not only in the minimum electrical field necessary to originate wave propagation, but also in the degree of influences of nearby defects. The distance between two defects, i.e. the density of defects, also play an important role in the WEH effect. Generally, the REF is better than the DEF when pulsed electric fields are applied. These results may contribute to the improved application of WEH, especially in older patients with fibrosis and scarring, which are accompanied by a higher incidence of conductivity discontinuities.

A Skin-attachable Flexible Piezoelectric Pulse Wave Energy Harvester

NASA Astrophysics Data System (ADS)

Yoon, Sunghyun; Cho, Young-Ho

2014-11-01

We present a flexible piezoelectric generator, capable to harvest energy from human arterial pulse wave on the human wrist. Special features and advantages of the flexible piezoelectric generator include the multi-layer device design with contact windows and the simple fabrication process for the higher flexibility with the better energy harvesting efficiency. We have demonstrated the design effectiveness and the process simplicity of our skin- attachable flexible piezoelectric pulse wave energy harvester, composed of the sensitive P(VDF-TrFE) piezoelectric layer on the flexible polyimide support layer with windows. We experimentally characterize and demonstrate the energy harvesting capability of 0.2~1.0μW in the Human heart rate range on the skin contact area of 3.71cm2. Additional physiological and/or vital signal monitoring devices can be fabricated and integrated on the skin attachable flexible generator, covered by an insulation layer; thus demonstrating the potentials and advantages of the present device for such applications to the flexible multi-functional selfpowered artificial skins, capable to detect physiological and/or vital signals on Human skin using the energy harvested from arterial pulse waves.

Broadband millimeter-wave GaAs transmitters and receivers using planar bow-tie antennas

NASA Technical Reports Server (NTRS)

Konishi, Y.; Kamegawa, M.; Case, M.; Yu, R.; Rodwell, M. J. W.; York, R. A.; Rutledge, D. B.

1992-01-01

We report broadband monolithic transmitters and receivers IC's for mm-wave electromagnetic measurements. The IC's use nonlinear transmission lines (NLTL) and sampling circuits as picosecond pulse generators and detectors. The pulses are radiated and received by planar monolithic bow-tie antennas, collimated with silicon substrate lenses and off-axis parabolic reflectors. Through Fourier transformation of the received pulse, 30-250 GHz free space gain-frequency measurements are demonstrated with an accuracy approximately = 0.17 dB, RMS.

Laser absorption waves in metallic capillaries

NASA Astrophysics Data System (ADS)

Anisimov, V. N.; Arutiunian, R. V.; Bol'Shov, L. A.; Kanevskii, M. F.; Kondrashov, V. V.

1987-07-01

The propagation of laser absorption waves in metallic capillaries was studied experimentally and numerically during pulsed exposure to CO2 laser radiation. The dependence of the plasma front propagation rate on the initial air pressure in the capillary is determined. In a broad range of parameters, the formation time of the optically opaque plasma layer is governed by the total laser pulse energy from the beginning of the exposure to the instant screening appears, and is weakly dependent on the pulse shape and gas pressure.

Tunable error-free optical frequency conversion of a 4ps optical short pulse over 25 nm by four-wave mixing in a polarisation-maintaining optical fibre

NASA Astrophysics Data System (ADS)

Morioka, T.; Kawanishi, S.; Saruwatari, M.

1994-05-01

Error-free, tunable optical frequency conversion of a transform-limited 4.0 ps optical pulse signalis demonstrated at 6.3 Gbit/s using four-wave mixing in a polarization-maintaining optical fibre. The process generates 4.0-4.6 ps pulses over a 25nm range with time-bandwidth products of 0.31-0.43 and conversion power penalties of less than 1.5 dB.

Generation of an incident focused light pulse in FDTD.

PubMed

Capoğlu, Ilker R; Taflove, Allen; Backman, Vadim

2008-11-10

A straightforward procedure is described for accurately creating an incident focused light pulse in the 3-D finite-difference time-domain (FDTD) electromagnetic simulation of the image space of an aplanatic converging lens. In this procedure, the focused light pulse is approximated by a finite sum of plane waves, and each plane wave is introduced into the FDTD simulation grid using the total-field/scattered-field (TF/SF) approach. The accuracy of our results is demonstrated by comparison with exact theoretical formulas.

Generation of an incident focused light pulse in FDTD

PubMed Central

Çapoğlu, İlker R.; Taflove, Allen; Backman, Vadim

2009-01-01

A straightforward procedure is described for accurately creating an incident focused light pulse in the 3-D finite-difference time-domain (FDTD) electromagnetic simulation of the image space of an aplanatic converging lens. In this procedure, the focused light pulse is approximated by a finite sum of plane waves, and each plane wave is introduced into the FDTD simulation grid using the total-field/scattered-field (TF/SF) approach. The accuracy of our results is demonstrated by comparison with exact theoretical formulas. PMID:19582013

Effect of positive pulse charge waveforms on the energy efficiency of lead-acid traction cells

NASA Technical Reports Server (NTRS)

Smithrick, J. J.

1981-01-01

The effects of four different charge methods on the energy conversion efficiency of 300 ampere hour lead acid traction cells were investigated. Three of the methods were positive pulse charge waveforms; the fourth, a constant current method, was used as a baseline of comparison. The positive pulse charge waveforms were: 120 Hz full wave rectified sinusoidal; 120 Hz silicon controlled rectified; and 1 kHz square wave. The constant current charger was set at the time average pulse current of each pulse waveform, which was 150 amps. The energy efficiency does not include charger losses. The lead acid traction cells were charged to 70 percent of rated ampere hour capacity in each case. The results of charging the cells using the three different pulse charge waveforms indicate there was no significant difference in energy conversion efficiency when compared to constant current charging at the time average pulse current value.

Development of a wearable system module for monitoring physical and mental workload.

PubMed

Kim, Sinbae; Nakamura, Hiromi; Yoshida, Toshihiko; Kishimoto, Masamichi; Imai, Yohsuke; Matsuki, Noriaki; Ishikawa, Takuji; Yamaguchi, Takami

2008-11-01

The population of most developed countries is rapidly aging, which has created a growing demand for home care. A key issue in medicine is supporting the increasing number of elderly patients, both physically and mentally. In this study, we developed a wearable computer that contained modules for measuring electrocardiograms (ECGs) and femoral artery pulse waves using an accelerometer. This system has several benefits: (a) it can provide a database server in each patient's home; (b) its high extendibility and flexibility facilitate adaptation to a patient's needs; and (c) it allows patients to keep their own data, thus protecting the privacy of personal information. To clarify the capabilities and reliability of the system, we applied it to 8 healthy young volunteers during states of physical and mental work. This system successfully detected clear ECGs and femoral artery pulse waves to calculate important bioinformation, including heart rate, pulse wave velocity, and the power spectral density of spontaneous beat-to-beat oscillations in the R-R interval. In this study, we proposed the way to provide an assessment of the physical and mental condition of the subject using analysis of the bio-information with respect to the physical and mental workloads. The present study provides useful knowledge for the development of a wearable computer designed to monitor the physical and mental conditions of older persons and patients.

A Fast Multimodal Ectopic Beat Detection Method Applied for Blood Pressure Estimation Based on Pulse Wave Velocity Measurements in Wearable Sensors.

PubMed

Pflugradt, Maik; Geissdoerfer, Kai; Goernig, Matthias; Orglmeister, Reinhold

2017-01-14

Automatic detection of ectopic beats has become a thoroughly researched topic, with literature providing manifold proposals typically incorporating morphological analysis of the electrocardiogram (ECG). Although being well understood, its utilization is often neglected, especially in practical monitoring situations like online evaluation of signals acquired in wearable sensors. Continuous blood pressure estimation based on pulse wave velocity considerations is a prominent example, which depends on careful fiducial point extraction and is therefore seriously affected during periods of increased occurring extrasystoles. In the scope of this work, a novel ectopic beat discriminator with low computational complexity has been developed, which takes advantage of multimodal features derived from ECG and pulse wave relating measurements, thereby providing additional information on the underlying cardiac activity. Moreover, the blood pressure estimations' vulnerability towards ectopic beats is closely examined on records drawn from the Physionet database as well as signals recorded in a small field study conducted in a geriatric facility for the elderly. It turns out that a reliable extrasystole identification is essential to unsupervised blood pressure estimation, having a significant impact on the overall accuracy. The proposed method further convinces by its applicability to battery driven hardware systems with limited processing power and is a favorable choice when access to multimodal signal features is given anyway.

Solid-state EPR strategies for the structural characterization of paramagnetic NO adducts of frustrated Lewis pairs (FLPs)

NASA Astrophysics Data System (ADS)

de Oliveira, Marcos; Wiegand, Thomas; Elmer, Lisa-Maria; Sajid, Muhammad; Kehr, Gerald; Erker, Gerhard; Magon, Claudio José; Eckert, Hellmut

2015-03-01

Anisotropic interactions present in three new nitroxide radicals prepared by N,N addition of NO to various borane-phosphane frustrated Lewis pairs (FLPs) have been characterized by continuous-wave (cw) and pulsed X-band EPR spectroscopies in solid FLP-hydroxylamine matrices at 100 K. Anisotropic g-tensor values and 11B, 14N, and 31P hyperfine coupling tensor components have been extracted from continuous-wave lineshape analyses, electron spin echo envelope modulation (ESEEM), and hyperfine sublevel correlation spectroscopy (HYSCORE) experiments with the help of computer simulation techniques. Suitable fitting constraints are developed on the basis of density functional theory (DFT) calculations. These calculations reveal that different from the situation in standard nitroxide radicals (TEMPO), the g-tensors are non-coincident with any of the nuclear hyperfine interaction tensors. The determination of these interaction parameters turns out to be successful, as the cw- and pulse EPR experiments are highly complementary in informational content. While the continuous-wave lineshape is largely influenced by the anisotropic hyperfine coupling to 14N and 31P, the ESEEM and HYSCORE spectra contain important information about the 11B hyperfine coupling and nuclear electric quadrupolar interaction. The set of cw- and pulsed EPR experiments, with fitting constraints developed by DFT calculations, defines an efficient strategy for the structural analysis of paramagnetic FLP adducts.

Solid-state EPR strategies for the structural characterization of paramagnetic NO adducts of frustrated Lewis pairs (FLPs)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Oliveira, Marcos de; Magon, Claudio José; Wiegand, Thomas

2015-03-28

Anisotropic interactions present in three new nitroxide radicals prepared by N,N addition of NO to various borane-phosphane frustrated Lewis pairs (FLPs) have been characterized by continuous-wave (cw) and pulsed X-band EPR spectroscopies in solid FLP-hydroxylamine matrices at 100 K. Anisotropic g-tensor values and {sup 11}B, {sup 14}N, and {sup 31}P hyperfine coupling tensor components have been extracted from continuous-wave lineshape analyses, electron spin echo envelope modulation (ESEEM), and hyperfine sublevel correlation spectroscopy (HYSCORE) experiments with the help of computer simulation techniques. Suitable fitting constraints are developed on the basis of density functional theory (DFT) calculations. These calculations reveal that differentmore » from the situation in standard nitroxide radicals (TEMPO), the g-tensors are non-coincident with any of the nuclear hyperfine interaction tensors. The determination of these interaction parameters turns out to be successful, as the cw- and pulse EPR experiments are highly complementary in informational content. While the continuous-wave lineshape is largely influenced by the anisotropic hyperfine coupling to {sup 14}N and {sup 31}P, the ESEEM and HYSCORE spectra contain important information about the {sup 11}B hyperfine coupling and nuclear electric quadrupolar interaction. The set of cw- and pulsed EPR experiments, with fitting constraints developed by DFT calculations, defines an efficient strategy for the structural analysis of paramagnetic FLP adducts.« less

Morning blood pressure surge and arterial stiffness in newly diagnosed hypertensive patients.

PubMed

Kıvrak, Ali; Özbiçer, Süleyman; Kalkan, Gülhan Yüksel; Gür, Mustafa

2017-06-01

We aimed to investigate the relationship between the morning blood pressure (BP) surge and arterial stiffness in patients with newly diagnosed hypertension. Three hundred and twenty four (mean age 51.7 ± 11.4 years) patients who had newly diagnosed hypertension with 24 h ambulatory BP monitoring were enrolled. Parameters of arterial stiffness, pulse wave velocity and augmentation index (Aix) were measured by applanation tonometry and aortic distensibility was calculated by echocardiography. Compared with the other groups, pulse wave velocity, day-night systolic BP (SBP) difference (p < 0.001, for all) and hs-CRP (p = 0.005) were higher in morning BP surge high group. Aortic distensibility values were significantly lower in morning BP surge high group compared to the other groups (p < 0.05, for all). Morning BP surge was found to be independently associated with pulse wave velocity (β = 0.286, p < 0.001), aortic distensibility (β= -0.384, p < 0.001) and day-night SBP difference (β = 0.229, p < 0.001) in multivariate linear regression analysis. We found independent relationship between morning BP surge and arterial stiffness which is a surrogate endpoint for cardiovascular diseases. The inverse relationship between morning BP surge and aortic distensibility and direct relation found in our study is new to the literature.

Relative Position of the Third Characteristic Peak of the Intracranial Pressure Pulse Waveform Morphology Differentiates Normal-Pressure Hydrocephalus Shunt Responders and Nonresponders.

PubMed

Hamilton, Robert; Fuller, Jennifer; Baldwin, Kevin; Vespa, Paul; Hu, Xiao; Bergsneider, Marvin

2016-01-01

The diversion of cerebrospinal fluid (CSF) remains the principal treatment option for patients with normal-pressure hydrocephalus (NPH). External lumbar drain (ELD) and overnight intracranial pressure (ICP) monitoring are popular prognostic tests for differentiating which patients will benefit from shunting. Using the morphological clustering and analysis of continuous intracranial pulse (MOCAIP) algorithm to extract morphological metrics from the overnight ICP signal, we hypothesize that changes in the third peak of the ICP pulse pressure waveform can be used to differentiate ELD responders and nonresponders. Our study involved 66 patients (72.2 ± 9.8 years) undergoing evaluation for possible NPH, which included overnight ICP monitoring and ELD. ELD outcome was based on clinical notes and divided into nonresponders and responders. MOCAIP was used to extract mean ICP, ICP wave amplitude (waveAmp), and a metric derived to study P3 elevation (P3ratio). Of the 66 patients, 7 were classified as nonresponders and 25 as significant responders. The mean ICP and waveAmp did not vary significantly (p = 0.19 and p = 0.41) between the outcome groups; however, the P3ratio did show a significant difference (p = 0.04). Initial results suggest that the P3ratio might be used as a prognostic indicator for ELD outcome.

Wave propagation in a strongly nonlinear locally resonant granular crystal

NASA Astrophysics Data System (ADS)

Vorotnikov, K.; Starosvetsky, Y.; Theocharis, G.; Kevrekidis, P. G.

2018-02-01

In this work, we study the wave propagation in a recently proposed acoustic structure, the locally resonant granular crystal. This structure is composed of a one-dimensional granular crystal of hollow spherical particles in contact, containing linear resonators. The relevant model is presented and examined through a combination of analytical approximations (based on ODE and nonlinear map analysis) and of numerical results. The generic dynamics of the system involves a degradation of the well-known traveling pulse of the standard Hertzian chain of elastic beads. Nevertheless, the present system is richer, in that as the primary pulse decays, secondary ones emerge and eventually interfere with it creating modulated wavetrains. Remarkably, upon suitable choices of parameters, this interference "distills" a weakly nonlocal solitary wave (a "nanopteron"). This motivates the consideration of such nonlinear structures through a separate Fourier space technique, whose results suggest the existence of such entities not only with a single-side tail, but also with periodic tails on both ends. These tails are found to oscillate with the intrinsic oscillation frequency of the out-of-phase motion between the outer hollow bead and its internal linear attachment.

Ultra-bright GeV photon source via controlled electromagnetic cascades in laser-dipole waves

NASA Astrophysics Data System (ADS)

Gonoskov, Arkady; Bashinov, Alexey; Efimenko, Evgeny; Muraviev, Alexander; Kim, Arkady; Ilderton, Anton; Bastrakov, Sergey; Meyerov, Iosif; Marklund, Mattias; Sergeev, Alexander

2017-10-01

The prospect of achieving conditions for triggering strong-field QED phenomena at upcoming large-scale laser facilities raises a number of intriguing questions. What kind of new effects and interaction regimes can be accessed by basic QED phenomena? What are the minimal (optimal) requirements to trigger these effects and enter these regimes? How can we, from this, gain new fundamental knowledge or create important applications? The talk will concern the prospects of producing high fluxes of GeV photons by triggering a special type of self-sustaining cascade in the field of several colliding laser pulses that form a dipole wave. Apart from reaching the highest field strength for a given total power of laser pulses, the dipole wave enables anomalous radiative trapping that favors pair production and high-energy photon generation. An extensive theoretical analysis and 3D QED-PIC simulations indicate that the concept is feasible at upcoming large-scale laser facilities of 10 PW level and can provide an extraordinary intense source of GeV photons for novel experimental studies in nuclear and quark-nuclear physics.

A comparison of light spot hydrophone and fiber optic probe hydrophone for lithotripter field characterization.

PubMed

Smith, N; Sankin, G N; Simmons, W N; Nanke, R; Fehre, J; Zhong, P

2012-01-01

The performance of a newly developed light spot hydrophone (LSHD) in lithotripter field characterization was compared to that of the fiber optic probe hydrophone (FOPH). Pressure waveforms produced by a stable electromagnetic shock wave source were measured by the LSHD and FOPH under identical experimental conditions. In the low energy regime, focus and field acoustic parameters matched well between the two hydrophones. At clinically relevant high energy settings for shock wave lithotripsy, the measured leading compressive pressure waveforms matched closely with each other. However, the LSHD recorded slightly larger |P_| (p < 0.05) and secondary peak compressive pressures (p < 0.01) than the FOPH, leading to about 20% increase in total acoustic pulse energy calculated in a 6 mm radius around the focus (p = 0.06). Tensile pulse durations deviated ~5% (p < 0.01) due to tensile wave shortening from cavitation activity using the LSHD. Intermittent compression spikes and laser light reflection artifacts have been correlated to bubble activity based on simultaneous high-speed imaging analysis. Altogether, both hydrophones are adequate for lithotripter field characterization as specified by the international standard IEC 61846.

Adiabatic description of superfocusing of femtosecond plasmon polaritons

NASA Astrophysics Data System (ADS)

Golovinski, P. A.; Manuylovich, E. S.; Astapenko, V. A.

2018-05-01

A surface plasmon polariton is a collective oscillation of free electrons at a metal-dielectric interface. As wave phenomena, surface plasmon polaritons can be focused with the use of an appropriate excitation geometry of metal structures. In the adiabatic approximation, we demonstrate a possibility to control nanoscale short pulse superfocusing based on generation of a radially polarized surface plasmon polariton mode of a conical metal needle in view of wave reflection. The results of numerical simulations of femtosecond pulse propagation along a nanoneedle are discussed. The space-time evolution of a pulse for the near field strongly depends on a linear chirp of an initial laser pulse, which can partially compensate wave dispersion. The field distribution is calculated for different metals, chirp parameters, cone opening angles and propagation distances. The electric field near a sharp tip is described as a field of a fictitious time-dependent electric dipole located at the tip apex.

Ultra-bright pulsed electron beam with low longitudinal emittance

DOEpatents

Zolotorev, Max

2010-07-13

A high-brightness pulsed electron source, which has the potential for many useful applications in electron microscopy, inverse photo-emission, low energy electron scattering experiments, and electron holography has been described. The source makes use of Cs atoms in an atomic beam. The source is cycled beginning with a laser pulse that excites a single Cs atom on average to a band of high-lying Rydberg nP states. The resulting valence electron Rydberg wave packet evolves in a nearly classical Kepler orbit. When the electron reaches apogee, an electric field pulse is applied that ionizes the atom and accelerates the electron away from its parent ion. The collection of electron wave packets thus generated in a series of cycles can occupy a phase volume near the quantum limit and it can possess very high brightness. Each wave packet can exhibit a considerable degree of coherence.

Recoverable stress induced two-way shape memory effect on NiTi surface using laser-produced shock wave

NASA Astrophysics Data System (ADS)

Seyitliyev, Dovletgeldi; Li, Peizhen; Kholikov, Khomidkhodza; Grant, Byron; Thomas, Zachary; Alal, Orhan; Karaca, Haluk E.; Er, Ali O.

2017-02-01

The surfaces of Ni50Ti50 shape memory alloys (SMAs) were patterned by laser scribing. This method is more simplistic and efficient than traditional indentation techniques, and has also shown to be an effective method in patterning these materials. Different laser energy densities ranging from 5 mJ/pulse to 56 mJ/pulse were used to observe recovery on SMA surface. The temperature dependent heat profiles of the NiTi surfaces after laser scribing at 56 mJ/pulse show the partially-recovered indents, which indicate a "shape memory effect (SME)" Experimental data is in good agreement with theoretical simulation of laser induced shock wave propagation inside NiTi SMAs. Stress wave closely followed the rise time of the laser pulse to its peak values and initial decay. Further investigations are underway to improve the SME such that the indents are recovered to a greater extent.

Laser-excited pulses in a crystallized dusty plasma

NASA Astrophysics Data System (ADS)

Nosenko, V.; Nunomura, S.; Goree, J.

2000-10-01

A dusty plasma is an ionized gas containing small particles of solid matter. These particles acquire a large negative electric charge. Polymer microspheres were shaken into a capacitively-coupled parallel-plate rf plasma. The particles were levitated by the electric field in the sheath above the lower electrode. The particles settled in a single horizontal layer, arranged in a hexagonal lattice. They were imaged using a video camera, to record the particle motion. Like any crystal, this so-called ``plasma crystal'' sustains compressional sound waves, which can be launched as a pulse. There are several ways these waves can be excited, including applying a force from the radiation pressure of a laser beam. By chopping an argon laser beam that is directed at the lattice, it is possible to launch a pulsed wave in the lattice. We evaluate the pulse's shape and propagation speed, and test whether it has the properties of a shock.

Search for Transient Gravitational Waves in Coincidence with Short-Duration Radio Transients During 2007-2013

NASA Technical Reports Server (NTRS)

Abbott, B. P.; Hughey, Brennan; Zanolin, Michele; Szczepanczyk, Marek; Gill, Kiranjyot; Abbott, R.; Abbott, T. D.; Abernathy, M. R.; Acernese, F.; Ackley, K.;

Imaging pulse wave velocity in mouse retina using swept-source OCT (Conference Presentation)

NASA Astrophysics Data System (ADS)

Song, Shaozhen; Wei, Wei; Wang, Ruikang K.

2016-03-01

Blood vessel dynamics has been a significant subject in cardiology and internal medicine, and pulse wave velocity (PWV) on artery vessels is a classic evaluation of arterial distensibility, and has never been ascertained as a cardiovascular risk marker. The aim of this study is to develop a high speed imaging technique to capture the pulsatile motion on mouse retina arteries with the ability to quantify PWV on any arterial vessels. We demonstrate a new non-invasive method to assess the vessel dynamics on mouse retina. A Swept-source optical coherence tomography (SS-OCT) system is used for imaging micro-scale blood vessel motion. The phase-stabilized SS-OCT provides a typical displacement sensitivity of 20 nm. The frame rate of imaging is ~16 kHz, at A-line rate of ~1.62 MHz, which allows the detection of transient pulse waves with adequate temporal resolution. Imaging volumes with repeated B-scans are obtained on mouse retina capillary bed, and the mouse oxymeter signal is recorded simultaneously. The pulse wave on artery and vein are resolved, and with the synchronized heart beat signal, the temporal delay on different vessel locations is determined. The vessel specific measurement of PWV is achieved for the first time with SS-OCT, for pulse waves propagating more than 100 cm/s. Using the novel methodology of retinal PWV assessment, it is hoped that the clinical OCT scans can provide extended diagnostic information of cardiology functionalities.

Observation of strong oscillations of areal mass in an unsupported shock wave produced by a short laser pulse

NASA Astrophysics Data System (ADS)

Aglitskiy, Y.; Karasik, M.; Velikovich, A. L.; Serlin, V.; Weaver, J. L.; Kessler, T. J.; Schmitt, A. J.; Obenschain, S. P.; Metzler, N.; Oh, J.

2011-10-01

The first experimental study of hydrodynamic perturbation evolution in a strong unsupported shock wave, which is immediately followed by a rarefaction wave, is reported. Our planar solid polystyrene laser-machined targets, 50 to 100 μm thick, rippled from the front side with a single-mode wavelength 30 or 45 μm and peak-to-valley amplitude 4 to 6 μm, were irradiated with a 350 ps long Nike KrF laser pulse at peak intensity of up to 330 TW/cm2. The perturbation evolution in the target was observed using face-on monochromatic x-ray radiography while the pulse lasted and for 3 to 4 ns after it ended. While the driving pulse was on, the areal mass modulation amplitude in the target was observed to grow by a factor of up to ~4 due to the ablative Richtmyer-Meshkov instability. After the end of the pulse, while the strong unsupported shock wave propagated through the unperturbed target, the theoretically predicted large oscillations of the areal mass [A. L. Velikovich et al., Phys. Plasmas 10, 3270 (2003)] were observed. Multiple phase reversals of the areal mass modulation have been detected. Work supported by DOE/NNSA and Office of Naval Research.

Noncollinear wave mixing of attosecond XUV and few-cycle optical laser pulses in gas-phase atoms: Toward multidimensional spectroscopy involving XUV excitations

NASA Astrophysics Data System (ADS)

Cao, Wei; Warrick, Erika R.; Fidler, Ashley; Neumark, Daniel M.; Leone, Stephen R.

2016-11-01

Ultrafast nonlinear spectroscopy, which records transient wave-mixing signals in a medium, is a powerful tool to access microscopic information using light sources in the radio-frequency and optical regimes. The extension of this technique towards the extreme ultraviolet (XUV) or even x-ray regimes holds the promise to uncover rich structural or dynamical information with even higher spatial or temporal resolution. Here, we demonstrate noncollinear wave mixing between weak XUV attosecond pulses and a strong near-infrared (NIR) few-cycle laser pulse in gas phase atoms (one photon of XUV and two photons of NIR). In the noncollinear geometry the attosecond and either one or two NIR pulses interact with argon atoms. Nonlinear XUV signals are generated in a spatially resolved fashion as required by phase matching. Different transition pathways can be identified from these background-free nonlinear signals according to the specific phase-matching conditions. Time-resolved measurements of the spatially gated XUV signals reveal electronic coherences of Rydberg wave packets prepared by a single XUV photon or XUV-NIR two-photon excitation, depending on the applied pulse sequences. These measurements open possible applications of tabletop multidimensional spectroscopy to the study of dynamics associated with valence or core excitation with XUV photons.

Influence of Controlled Viscous Dissipation on Propagation of Strongly Nonlinear Waves in Steel-Based Phononic Crystals

NASA Astrophysics Data System (ADS)

Herbold, Eric

2005-07-01

Strongly nonlinear phononic crystals were assembled from chains of stainless steel spheres with diameter 4.78 mm. Propagation of solitary waves and splitting of initial pulse into train of solitary waves excited by the impact of piston was investigated in different viscous media in experiments and in numerical calculations. Oil of various grades was used to introduce controlled dissipation into the system. Preliminary results indicate that splitting of the initial pulse into the train of solitary waves was dramatically influenced by viscosity. This work was supported by NSF (Grant No. DCMS03013220).

Ultra-fast magnetic vortex core reversal by a local field pulse

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rückriem, R.; Albrecht, M., E-mail: manfred.albrecht@physik.uni-augsburg.de; Schrefl, T.

2014-02-03

Magnetic vortex core reversal of a 20-nm-thick permalloy disk with a diameter of 100 nm was studied by micromagnetic simulations. By applying a global out-of-plane magnetic field pulse, it turned out that the final core polarity is very sensitive to pulse width and amplitude, which makes it hard to control. The reason for this phenomenon is the excitation of radial spin waves, which dominate the reversal process. The excitation of spin waves can be strongly suppressed by applying a local field pulse within a small area at the core center. With this approach, ultra-short reversal times of about 15 ps weremore » achieved, which are ten times faster compared to a global pulse.« less

Attosecond pulse carrier-envelope phase effects on ionized electron momentum and energy distributions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Peng, L.-Y.; Starace, Anthony F.

2007-10-15

We analyze carrier-envelope phase (CEP) effects on electron wave-packet momentum and energy spectra produced by one or two few-cycle attosecond xuv pulses. The few-cycle attosecond pulses are assumed to have arbitrary phases. We predict CEP effects on ionized electron wave-packet momentum distributions produced by attosecond pulses having durations comparable to those obtained by Sansone et al. [Science 314, 443 (2006)]. The onset of significant CEP effects is predicted to occur for attosecond pulse field strengths close to those possible with current experimental capabilities. Our results are based on single-active-electron solutions of the three-dimensional, time-dependent Schroedinger equation including atomic potentials appropriatemore » for the H and He atoms.« less

Lithotripsy of gallstones by means of a quality-switched giant-pulse neodymium:yttrium-aluminum-garnet laser. Basic in vitro studies using a highly flexible fiber system.

PubMed

Hochberger, J; Gruber, E; Wirtz, P; Dürr, U; Kolb, A; Zanger, U; Hahn, E G; Ell, C

1991-11-01

The quality-switched neodymium:yttrium-aluminum-garnet laser represents a new instrument for athermal fragmentation of gallstones by transformation of optical energy into mechanical energy in the form of shock waves via local plasma formation. A highly flexible 300-micron fiber transmission system was used in basic investigations to determine the influence of varying pulse repetition rates (5-30 Hz) and pulse energies (15 and 20 mJ) on shock wave intensity and stone fragmentation in vitro for 105 biliary calculi of known size and chemical composition. After performance of 1200 shock wave pressure measurements using polyvinylidenefluoride hydrophones, stone fragmentation was analyzed by determination of fragment removal rates (volume of fragments removed per fragmentation time), ablation rates (mean volume removed per laser pulse), and median fragment sizes for each laser setting. With the quality-switched neodymium:yttrium-aluminum-garnet laser system, all concrements could be reliably disintegrated into small fragments (median diameter, 0.7-1.7 mm). Compared with pure cholesterol stones, a significantly higher fragment removal rate was achieved in cholesterol stones containing 30% calcium phosphate (P = 0.039), in cholesterol stones containing 20% pigment (P = 0.015), and in pure pigment stones (P = 0.007). Fragment removal rates, local shock wave pressures, and median grain sizes were significantly higher at a pulse energy of 20 mJ than with 15 mJ. Shock wave pressures showed a distinct dependence on pulse repetition rates at 20 mJ, yet not at 15 mJ. Because there is no evident hazard of thermal damage to tissue using the quality-switched neodymium:yttrium-aluminum-garnet laser, it appears to be a promising device for nonsurgical biliary stone therapy.

Rayleigh wave acoustic emission during crack propagation in steel

NASA Astrophysics Data System (ADS)

Horne, Michael R.

2003-07-01

An investigation was conducted of the existence of seismic surface pulses (SSP) on crack faces in near-failure fatigue. An SSP has components of various modes of wave propagation. The component with the largest amplitude is a Rayleigh surface wave pulse. The possibility that these surface modes have much higher amplitudes than bulk modes of acoustic emission (AE) was illustrated by an idealized thought experiment relating an SSP on a half-space to the response of crack faces to crack extension. A number of aspects of AE monitoring in finite objects were investigated. Attributes of surface wave propagation on the edge of a specimen were found to be easier to monitor than other modes of wave propagation. Wavelet analysis was used to compare the characteristics of brittle AE with other sources. A new testing paradigm was developed to reduce interference from secondary sources of AE and enhance the investigation of AE from critical crack behavior. Unique specimen design features were developed, data acquisition features sought and validated, a dead weight load frame was modified, and data analysis procedures were developed. Criteria based on velocity, frequency content, amplitude and shape were devised to determine if an AE event is an SSP. The tests were designed to mimic load conditions on structures such as bridges and hence investigate the difference between AE generated in field conditions and that of typical laboratory conditions. Varieties of steel, from very ductile to very brittle, were tested. It was concluded that plastic zone formation, considered a secondary source of AE, was found not to interfere with the SSP activity. The SSP was found experimentally to have 2-3 times the amplitude of the bulk wave AE. The lack of sufficient AE did not allow for determination of conclusive changes in the AE as the specimens approached failure. However, it was found that brittle crack extension in fatigue and ductile failure can produce wave propagation resembling the SSP.

Rayleigh wave acoustic emission during crack propagation in steel

NASA Astrophysics Data System (ADS)

Horne, Michael R.

An investigation was conducted of the existence of seismic surface pulses (SSP) on crack faces in near-failure fatigue. An SSP has components of various modes of wave propagation. The component with the largest amplitude is a Rayleigh surface wave pulse. The possibility that these surface modes have much higher amplitudes than bulk modes of acoustic emission (AE) was illustrated by an idealized thought experiment relating an SSP on a half-space to the response of crack faces to crack extension. A number of aspects of AE monitoring in finite objects were investigated. Attributes of surface wave propagation on the edge of a specimen were found to be easier to monitor than other modes of wave propagation. Wavelet analysis was used to compare the characteristics of brittle AE with other sources. A new testing paradigm was developed to reduce interference from secondary sources of AE and enhance the investigation of AE from critical crack behavior. Unique specimen design features were developed, data acquisition features sought and validated, a dead weight load frame was modified, and data analysis procedures were developed. Criteria based on velocity, frequency content, amplitude and shape were devised to determine if an AE event is an SSP. The tests were designed to mimic load conditions on structures such as bridges and hence investigate the difference between AE generated in field conditions and that of typical laboratory conditions. Varieties of steel, from very ductile to very brittle, were tested. It was concluded that plastic zone formation, considered a secondary source of AE, was found not to interfere with the SSP activity. The SSP was found experimentally to have 2-3 times the amplitude of the bulk wave AE. The lack of sufficient AE did not allow for determination of conclusive changes in the AE as the specimens approached failure. However, it was found that brittle crack extension in fatigue and ductile failure can produce wave propagation resembling the SSP.

High-Speed, High-Resolution Time-to-Digital Conversion

NASA Technical Reports Server (NTRS)

Katz, Richard; Kleyner, Igor; Garcia, Rafael

2013-01-01

This innovation is a series of time-tag pulses from a photomultiplier tube, featuring short time interval between pulses (e.g., 2.5 ns). Using the previous art, dead time between pulses is too long, or too much hardware is required, including a very-high-speed demultiplexer. A faster method is needed. The goal of this work is to provide circuits to time-tag pulses that arrive at a high rate using the hardwired logic in an FPGA - specifically the carry chain - to create what is (in effect) an analog delay line. High-speed pulses travel down the chain in a "wave." For instance, a pulse train has been demonstrated from a 1- GHz source reliably traveling down the carry chain. The size of the carry chain is over 10 ns in the time domain. Thus, multiple pulses will travel down the carry chain in a wave simultaneously. A register clocked by a low-skew clock takes a "snapshot" of the wave. Relatively simple logic can extract the pulses from the snapshot picture by detecting the transitions between logic states. The propagation delay of CMOS (complementary metal oxide semiconductor) logic circuits will differ and/or change as a result of temperature, voltage, age, radiation, and manufacturing variances. The time-to-digital conversion circuits can be calibrated with test signals, or the changes can be nulled by a separate on-die calibration channel, in a closed loop circuit.

[Aspects of vascular physiology in clinical and vascular surgical practice: basic principles of vascular mechanics].

PubMed

Nocke, H; Meyer, F; Lessmann, V

2014-10-01

To be able to evaluate properly a vascular problem, basic concepts of vascular physiology need to be considered, as they have been taught in physiology for a long time. This article deals with selected definitions and laws of passive vascular mechanics, subdivided into parameters of vascular filling and parameters of vascular flow. PARAMETERS OF VASCULAR FILLING: During vascular filling the transmural pressure distends the vascular wall until it is balanced by the wall tension. The extent of this distension up to the point of balance depends on the elasticity of the wall. Transmural pressure, wall tension and elasticity are defined, and their respective importance is described by clinical examples, e.g. aneurysm and varix. PARAMETERS OF VASCULAR FLOW: The vascular flow can be divided into stationary and pulsating components. Both components are relevant for the bloodstream. Since the blood flow is directed in the circuit, it can be understood in first approximation as stationary ("direct current").The direct current model uses only the average values of the pulsating variables. The great advantage of the direct current model is that it can be described with simple laws, which are not valid without reservation, but often allow a first theoretical approach to a vascular problem: Ohm's law, driving pressure, flow resistance, Hagen-Poiseuille law, wall shear stress, law of continuity, Bernoulli's equation and Reynold's number are described and associated with clinical examples.The heart is a pressure-suction pump and produces a pulsating flow, the pulse. The pulse runs with pulse wave velocity, which is much larger than the blood flow velocity, through the arterial vascular system. During propagation, the pulse has to overcome the wave resistance (impedance). Wherever the wave resistance changes, e.g., at vascular bifurcations and in the periphery, it comes to reflections. The incident (forward) and reflected (backward) waves are superimposed to yield the resulting pulse wave. This pulse wave allows one to distinguish pressure and flow pulse by measurement. Both are described separately, and their respective clinical meaning is illustrated by appropriate examples, e.g., arterial stiffness and pre-/postocclusive high/low resistance flow, respectively. Georg Thieme Verlag KG Stuttgart · New York.

Influence of waveform and current direction on short-interval intracortical facilitation: a paired-pulse TMS study.

PubMed

Delvendahl, Igor; Lindemann, Hannes; Jung, Nikolai H; Pechmann, Astrid; Siebner, Hartwig R; Mall, Volker

2014-01-01

Transcranial magnetic stimulation (TMS) of the human primary motor hand area (M1-HAND) can produce multiple descending volleys in fast-conducting corticospinal neurons, especially so-called indirect waves (I-waves) resulting from trans-synaptic excitation. Facilitatory interaction between these I-waves can be studied non-invasively using a paired-pulse paradigm referred to as short-interval intracortical facilitation (SICF). We examined whether SICF depends on waveform and current direction of the TMS pulses. In young healthy volunteers, we applied single- and paired-pulse TMS to M1-HAND. We probed SICF by pairs of monophasic or half-sine pulses at suprathreshold stimulation intensity and inter-stimulus intervals (ISIs) between 1.0 and 5.0 ms. For monophasic paired-pulse stimulation, both pulses had either a posterior-anterior (PA) or anterior-posterior (AP) current direction (AP-AP or PA-PA), whereas current direction was reversed between first and second pulse for half-sine paired-pulse stimulation (PA-AP and AP-PA). Monophasic AP-AP stimulation resulted in stronger early SICF at 1.4 ms relative to late SICF at 2.8 and 4.4 ms, whereas monophasic PA-PA stimulation produced SICF of comparable size at all three peaks. With half-sine stimulation the third SICF peak was reduced for PA-AP current orientation compared with AP-PA. SICF elicited using monophasic as well as half-sine pulses is affected by current direction at clearly suprathreshold intensities. The impact of current orientation is stronger for monophasic compared with half-sine pulses. The direction-specific effect of paired-pulse TMS on the strength of early versus late SICF shows that different cortical circuits mediate early and late SICF. Copyright © 2014 Elsevier Inc. All rights reserved.

Stabilization and Structure of wave packets in Rydberg atoms ionized by a strong light field.

PubMed

Fedorov, M; Fedorov, S

1998-09-28

New features of the phenomenon of interference stabilization of Rydberg atoms are found to exist. The main of them are: (i) dynamical stabilization, which means that in case of pulses with a smooth envelope the time-dependent residual probability for an atom to survive in bound states remains almost constant in the middle part of a pulse (at the strongest fields); (ii) existence of the strong-field stabilization of the after-pulse residual probability in case of pulses longer than the classical Kepler period; and (iii) pulsation of the time-dependent Rydberg wave packet formed in the process of photoionization.

Supression of laser breakdown by pulsed nonequilibrium ns discharge

NASA Astrophysics Data System (ADS)

Starikovskiy, A. Y.; Semenov, I. E.; Shneider, M. N.

2016-10-01

The avalanche ionization induced by infrared laser pulses was investigated in a pre-ionized argon gas. Pre-ionization was created by a high-voltage pulsed nanosecond discharge developed in the form of a fast ionization wave. Then, behind the front of ionization wave additional avalanche ionization was initiated by the focused Nd-YAG laser pulse. It was shown that the gas pre-ionization inhibits the laser spark generation. It was demonstrated that the suppression of laser spark development in the case of strong gas pre-ionization is because of fast electron energy transfer from the laser beam focal region. The main mechanism of this energy transfer is free electrons diffusion.

Arterial Stiffness in Children: Pediatric Measurement and Considerations

PubMed Central

Savant, Jonathan D.; Furth, Susan L.; Meyers, Kevin E.C.

2014-01-01

Background Arterial stiffness is a natural consequence of aging, accelerated in certain chronic conditions, and predictive of cardiovascular events in adults. Emerging research suggests the importance of arterial stiffness in pediatric populations. Methods There are different indices of arterial stiffness. The present manuscript focuses on carotid-femoral pulse wave velocity and pulse wave analysis, although other methodologies are discussed. Also reviewed are specific measurement considerations for pediatric populations and the literature describing arterial stiffness in children with certain chronic conditions (primary hypertension, obesity, diabetes, chronic kidney disease, hypercholesterolemia, genetic syndromes involving vasculopathy, and solid organ transplant recipients). Conclusions The measurement of arterial stiffness in children is feasible and, under controlled conditions, can give accurate information about the underlying state of the arteries. This potentially adds valuable information about the functionality of the cardiovascular system in children with a variety of chronic diseases well beyond that of the brachial artery blood pressure. PMID:26587447

Arcing in Leo and Geo Simulated Environments: Comparative Analysis

NASA Technical Reports Server (NTRS)

Vayner, Boris V.; Ferguson, Dale C.; Galofaro, Joel TY.

2006-01-01

Comprehensive tests of two solar array samples in simulated Low Earth Orbit (LEO) and Geosynchronous Orbit (GEO) environments have demonstrated that the arc inception voltage was 2-3 times lower in the LEO plasma than in the GEO vacuum. Arc current pulse wave forms are also essentially different in these environments. Moreover, the wide variations of pulse forms do not allow introducing the definition of a "standard arc wave form" even in GEO conditions. Visual inspection of the samples after testing in a GEO environment revealed considerable damage on coverglass surfaces and interconnects. These harmful consequences can be explained by the discharge energy being one order of magnitude higher in vacuum than in background plasma. The tests also revealed a potential danger of powerful electrostatic discharges that could be initiated on the solar array surface of a satellite in GEO during the ignition of an arcjet thruster.

Ultrasonic and metallographic studies on AISI 4140 steel exposed to hydrogen at high pressure and temperature

NASA Astrophysics Data System (ADS)

Oruganti, Malavika

This thesis conducts an investigation to study the effects of hydrogen exposure at high temperature and pressure on the behavior of AISI 4140 steel. Piezoelectric ultrasonic technique was primarily used to evaluate surface longitudinal wave velocity and defect geometry variations, as related to time after exposure to hydrogen at high temperature and pressure. Critically refracted longitudinal wave technique was used for the former and pulse-echo technique for the latter. Optical microscopy and scanning electron microscopy were used to correlate the ultrasonic results with the microstructure of the steel and to provide better insight into the steel behavior. The results of the investigation indicate that frequency analysis of the defect echo, determined using the pulse-echo technique at regular intervals of time, appears to be a promising tool for monitoring defect growth induced by a high temperature and high pressure hydrogen-related attack.

Device and method for imaging of non-linear and linear properties of formations surrounding a borehole

DOEpatents

Johnson, Paul A; Tencate, James A; Le Bas, Pierre-Yves; Guyer, Robert; Vu, Cung Khac; Skelt, Christopher

2013-11-05

In some aspects of the disclosure, a method and an apparatus is disclosed for investigating material surrounding the borehole. The method includes generating a first low frequency acoustic wave within the borehole, wherein the first low frequency acoustic wave induces a linear and a nonlinear response in one or more features in the material that are substantially perpendicular to a radius of the borehole; directing a first sequence of high frequency pulses in a direction perpendicularly with respect to the longitudinal axis of the borehole into the material contemporaneously with the first acoustic wave; and receiving one or more second high frequency pulses at one or more receivers positionable in the borehole produced by an interaction between the first sequence of high frequency pulses and the one or more features undergoing linear and nonlinear elastic distortion due to the first low frequency acoustic wave to investigate the material surrounding the borehole.

On a method computing transient wave propagation in ionospheric regions

NASA Technical Reports Server (NTRS)

Gray, K. G.; Bowhill, S. A.

1978-01-01

A consequence of an exoatmospheric nuclear burst is an electromagnetic pulse (EMP) radiated from it. In a region far enough away from the burst, where nonlinear effects can be ignored, the EMP can be represented by a large-amplitude narrow-time-width plane-wave pulse. If the ionosphere intervenes the origin and destination of the EMP, frequency dispersion can cause significant changes in the original pulse upon reception. A method of computing these dispersive effects of transient wave propagation is summarized. The method described is different from the standard transform techniques and provides physical insight into the transient wave process. The method, although exact, can be used in approximating the early-time transient response of an ionospheric region by a simple integration with only explicit knowledge of the electron density, electron collision frequency, and electron gyrofrequency required. As an illustration of the method, it is applied to a simple example and contrasted with the corresponding transform solution.

Characteristics of 1.9 μm laser emission from hydrogen-filled hollow-core fiber by stimulated Raman scattering

NASA Astrophysics Data System (ADS)

Gu, Bo; Chen, Yubin; Wang, Zefeng

2016-11-01

We report here the detailed characteristics of 1.9 μm laser emission from hydrogen-filled hollow-core fiber by stimulated Raman scattering. A 6.5 m hydrogen-filled Ice-cream negative curvature hollow-core fiber is pumped with a high peak power, narrow linewidth, liner polarized subnanosecond pulsed 1064 nm microchip laser, generating pulsed 1908.5 nm vibrational Stokes wave. The linewidth of the pump laser and the vibrational Stokes wave is about 1 GHz and 2 GHz respectively. And the maximum Raman conversion quantum efficiency is about 48%. We also studied the pulse shapes of the pump laser and the vibrational Stokes wave. The polarization dependence of the vibrational and the rotational stimulated Raman scattering is also investigated. In addition, the beam profile of vibrational Stokes wave shows good quality, which may be taken advantage of in many applications.

Intrinsic Frequency and the Single Wave Biopsy

PubMed Central

Petrasek, Danny; Pahlevan, Niema M.; Tavallali, Peyman; Rinderknecht, Derek G.; Gharib, Morteza

2015-01-01

Insulin resistance is the hallmark of classical type II diabetes. In addition, insulin resistance plays a central role in metabolic syndrome, which astonishingly affects 1 out of 3 adults in North America. The insulin resistance state can precede the manifestation of diabetes and hypertension by years. Insulin resistance is correlated with a low-grade inflammatory condition, thought to be induced by obesity as well as other conditions. Currently, the methods to measure and monitor insulin resistance, such as the homeostatic model assessment and the euglycemic insulin clamp, can be impractical, expensive, and invasive. Abundant evidence exists that relates increased pulse pressure, pulse wave velocity (PWV), and vascular dysfunction with insulin resistance. We introduce a potential method of assessing insulin resistance that relies on a novel signal-processing algorithm, the intrinsic frequency method (IFM). The method requires a single pulse pressure wave, thus the term “ wave biopsy.” PMID:26183600

Cavitation clouds created by shock scattering from bubbles during histotripsy

PubMed Central

Maxwell, Adam D.; Wang, Tzu-Yin; Cain, Charles A.; Fowlkes, J. Brian; Sapozhnikov, Oleg A.; Bailey, Michael R.; Xu, Zhen

2011-01-01

Histotripsy is a therapy that focuses short-duration, high-amplitude pulses of ultrasound to incite a localized cavitation cloud that mechanically breaks down tissue. To investigate the mechanism of cloud formation, high-speed photography was used to observe clouds generated during single histotripsy pulses. Pulses of 5−20 cycles duration were applied to a transparent tissue phantom by a 1-MHz spherically focused transducer. Clouds initiated from single cavitation bubbles that formed during the initial cycles of the pulse, and grew along the acoustic axis opposite the propagation direction. Based on these observations, we hypothesized that clouds form as a result of large negative pressure generated by the backscattering of shockwaves from a single bubble. The positive-pressure phase of the wave inverts upon scattering and superimposes on the incident negative-pressure phase to create this negative pressure and cavitation. The process repeats with each cycle of the incident wave, and the bubble cloud elongates toward the transducer. Finite-amplitude propagation distorts the incident wave such that the peak-positive pressure is much greater than the peak-negative pressure, which exaggerates the effect. The hypothesis was tested with two modified incident waves that maintained negative pressure but reduced the positive pressure amplitude. These waves suppressed cloud formation which supported the hypothesis. PMID:21973343

THE NANOGRAV NINE-YEAR DATA SET: OBSERVATIONS, ARRIVAL TIME MEASUREMENTS, AND ANALYSIS OF 37 MILLISECOND PULSARS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Arzoumanian, Zaven; Brazier, Adam; Chatterjee, Shami

2015-11-01

We present high-precision timing observations spanning up to nine years for 37 millisecond pulsars monitored with the Green Bank and Arecibo radio telescopes as part of the North American Nanohertz Observatory for Gravitational Waves (NANOGrav) project. We describe the observational and instrumental setups used to collect the data, and methodology applied for calculating pulse times of arrival; these include novel methods for measuring instrumental offsets and characterizing low signal-to-noise ratio timing results. The time of arrival data are fit to a physical timing model for each source, including terms that characterize time-variable dispersion measure and frequency-dependent pulse shape evolution. Inmore » conjunction with the timing model fit, we have performed a Bayesian analysis of a parameterized timing noise model for each source, and detect evidence for excess low-frequency, or “red,” timing noise in 10 of the pulsars. For 5 of these cases this is likely due to interstellar medium propagation effects rather than intrisic spin variations. Subsequent papers in this series will present further analysis of this data set aimed at detecting or limiting the presence of nanohertz-frequency gravitational wave signals.« less

Pulse wave imaging using coherent compounding in a phantom and in vivo

NASA Astrophysics Data System (ADS)

Zacharias Apostolakis, Iason; McGarry, Matthew D. J.; Bunting, Ethan A.; Konofagou, Elisa E.

2017-03-01

Pulse wave velocity (PWV) is a surrogate marker of arterial stiffness linked to cardiovascular morbidity. Pulse wave imaging (PWI) is a technique developed by our group for imaging the pulse wave propagation in vivo. PWI requires high temporal and spatial resolution, which conventional ultrasonic imaging is unable to simultaneously provide. Coherent compounding is known to address this tradeoff and provides full aperture images at high frame rates. This study aims to implement PWI using coherent compounding within a GPU-accelerated framework. The results of the implemented method were validated using a silicone phantom against static mechanical testing. Reproducibility of the measured PWVs was assessed in the right common carotid of six healthy subjects (n  =  6) approximately 10-15 mm before the bifurcation during two cardiac cycles over the course of 1-3 d. Good agreement of the measured PWVs (3.97  ±  1.21 m s-1, 4.08  ±  1.15 m s-1, p  =  0.74) was obtained. The effects of frame rate, transmission angle and number of compounded plane waves on PWI performance were investigated in the six healthy volunteers. Performance metrics such as the reproducibility of the PWVs, the coefficient of determination (r 2), the SNR of the PWI axial wall velocities (\\text{SN}{{\\text{R}}{{\\text{v}_{\\text{PWI}}}}} ) and the percentage of lateral positions where the pulse wave appears to arrive at the same time-point, indicating inadequacy of the temporal resolution (i.e. temporal resolution misses) were used to evaluate the effect of each parameter. Compounding plane waves transmitted at 1° increments with a linear array yielded optimal performance, generating significantly higher r 2 and \\text{SN}{{\\text{R}}{{\\text{v}_{\\text{PWI}}}}} values (p  ⩽  0.05). Higher frame rates (⩾1667 Hz) produced improvements with significant gains in the r 2 coefficient (p  ⩽  0.05) and significant increase in both r 2 and \\text{SN}{{\\text{R}}{{\\text{v}_{\\text{PWI}}}}} from single plane wave imaging to 3-plane wave compounding (p  ⩽  0.05). Optimal performance was established at 2778 Hz with 3 plane waves and at 1667 Hz with 5 plane waves.

Photoplethysmography beyond perfusion and oxygenation monitoring: Pulse wave analysis for hepatic graft monitoring

DOE Office of Scientific and Technical Information (OSTI.GOV)

Akl, Tony; Wilson, Mark A.; Ericson, Milton Nance

2014-01-01

Photoplethysmography is a widely used technique in monitoring perfusion and blood oxygen saturation by using the amplitude of the pulsatile signal on one or multiple wavelengths. However, the pulsatile signal carries in its waveform a substantial amount of information about the mechanical properties of the tissue and vasculature under investigation that is still yet to be utilized to its full potential. In this work, we present the feasibility of pulse wave analysis for the application of monitoring hepatic implants and diagnosing graft complications. In particular, we show the possibility of computing the slope of the pulse during the diastole phasemore » to assess the location of vascular complications when they take place. This hypothesis was tested in a series of in vitro experiments using a PDMS based phantom mimicking the optical and mechanical properties of the portal vein. The emptying time of the vessel increased from 305 ms to 515 ms when an occlusion was induced downstream from the phantom. However, in the case of upstream occlusions, the emptying time remained constant. In both cases, a decrease in the amplitude of the pulse was recorded indicating the drop in flow levels. In addition, we show that quantifying the emptying time of the vasculature under investigation can be used to assess its compliance. The emptying time decreased from 305 ms for phantoms with compliance of 15 KPa to 195 ms for phantoms with compliance of 100 KPa. These compliance levels mimic those seen for normal and fibrotic hepatic tissue respectively.« less

Evolution of a primary pulse in the granular dimers mounted on a linear elastic foundation: An analytical and numerical study.

PubMed

Ahsan, Zaid; Jayaprakash, K R

2016-10-01

In this exposition we consider the wave dynamics of a one-dimensional periodic granular dimer (diatomic) chain mounted on a damped and an undamped linear elastic foundation (otherwise called the on-site potential). It is very well known that periodic granular dimers support solitary wave propagation (similar to that in the homogeneous granular chains) for a specific discrete set of mass ratios. In this work we present the analytical investigation of the evolution of solitary waves and primary pulses in granular dimers when they are mounted on on-site potential with and without velocity proportional foundation damping. We invoke a methodology based on the multiple time-scale asymptotic analysis and partition the dynamics of the perturbed dimer chain into slow and fast components. The dynamics of the dimer chain in the limit of large mass mismatch (auxiliary chain) mounted on on-site potential and foundation damping is used as the basis for the analysis. A systematic analytical procedure is then developed for the slowly varying response of the beads and in estimating primary pulse amplitude evolution resulting in a nonlinear map relating the relative displacement amplitudes of two adjacent beads. The methodology is applicable for arbitrary mass ratios between the beads. We present several examples to demonstrate the efficacy of the proposed method. It is observed that the amplitude evolution predicted by the described methodology is in good agreement with the numerical simulation of the original system. This work forms a basis for further application of the considered methodology to weakly coupled granular dimers which finds practical relevance in designing shock mitigating granular layers.

The Effect of Revascularization on the Hemodynamic Profile of Patients with Infrarenal Aortic Occlusion.

PubMed

Argyriou, Christos; Georgakarakos, Efstratios; Georgiadis, George S; Schoretsanitis, Nikolaos; Lazarides, Miltos K

2017-08-01

Patients undergoing revascularization for infrarenal aortic occlusion (IAO) have been reported to present improved survival rates compared to those treated conservatively. Aim of this study was to investigate the hemodynamic changes induced after revascularization for IAO, as expressed with pulse wave velocity (PWV), augmentation index (Aix), augmentation pressure (AP), and pulse wave reflection coefficient (RC). Twelve patients underwent revascularization (9 aortobifemoral/aortobiiliac bypasses, 2 primary iliac stenting, and 1 hybrid procedure of unilateral aortoiliac stenting and crossover bypass). Calculation of hemodynamic parameters was performed in all patients preoperatively, at 1 month, and 1 year postoperatively. Pulse wave analysis was performed noninvasively with a novel validated brachial cuff-based automatic oscillometric device (Mobil-O-Graph; IEM, Stolberg, Germany). The estimated hemodynamic parameters were AIx, AP, RC, and PWV. Data were analyzed with the Friedman analysis of variance test. Aix decreased significantly at 1 month and further at 1 year postoperatively compared to preoperative values (24 ± 11 and 17 ± 13 vs. 34 ± 13.5, respectively, P = 0.0006). AP decreased at 1 month and 1 year postoperatively compared to preoperative values (6.5 ± 4 mm Hg and 8 ± 6.5 mm Hg vs. 13 ± 12 mm Hg, respectively, P = 0.045). RC decreased also at 1-month and 1-year postoperatively compared to preoperative values (62 ± 5.5, 64 ± 4.3 vs. 73 ± 5.1, respectively, P = 0.002). However, changes in PWV were less prominent in this short-term postoperative period. Improved hemodynamic profile may theoretically contribute to the enhanced survival rates of these patients. Copyright © 2017 Elsevier Inc. All rights reserved.

Multi-beam laser-induced hydrodynamic shock waves used for delivery of microparticles and liquids in skin.

PubMed

Belikov, Andrey V; Skrypnik, Alexei V; Shatilova, Ksenia V; Tuchin, Valery V

2015-11-01

Laser radiation is often used to provide micro and nanoparticle delivery into the skin for medical and cosmetic purposes. This technique inherently has limited speed and effective penetration. We proposed and investigated a new method of rapid delivery of solid microparticles, nanoparticles and liquids into tissue through multiple microchannels created by a fractional laser microablation (FLMA) using Er:YAG-laser. The dependence of microchannel depth on laser pulse temporal structure and number of pulses and dermal coloration changes are studied in this paper. Microchannels created in the porcine skin in vitro by a fractional Er:YAG-laser were used to deliver Zirconium oxide (ZrO2) microparticles or hydrocortisone solution. Each laser pulse consisted of subpulses. Number of laser pulses (Np) and subpulses (Nsp) can be adjusted. The enhancement of delivery is expected due to hydrodynamic impact of laser pulse on the layer of the aqueous suspension of the particles or hydrocortisone solution placed on the skin surface. For color investigation, we used standard CIE Lab parameter analysis. The relationship between microchannel depth in the skin and number of laser pulses and subpulses was established. We found that free filling of microchannels with ZrO2-particle suspension has a low speed of ∼4 × 10(-5)  mm/s. Particle delivery into microchannels induced by the hydrodynamic shock waves generated by Er:YAG-laser pulses is carried out with a high speed of 28.5 mm/s. We also found that skin color at ZrO2 -particle delivery differs from color of the intact skin, namely: the parameter L, which characterizes the "lightness" increased by 9 ± 1%; parameter a, which characterizes the "redness" decreased by 38 ± 4%; and parameter b, which characterizes the "yellowness" decreased by 21 ± 2%. The effective delivery of hydrocortisone was demonstrated using fluorescence method technique. Multi-beam laser-induced hydrodynamic shock waves generated by Er:YAG-laser pulses on the layer of the aqueous suspension of the particles or solution of a high molecular weight drug placed on the skin can be used for their rapid delivery into the skin. © 2015 Wiley Periodicals, Inc.

A FBG pulse wave demodulation method based on PCF modal interference filter

NASA Astrophysics Data System (ADS)

Zhang, Cheng; Xu, Shan; Shen, Ziqi; Zhao, Junfa; Miao, Changyun; Bai, Hua

2016-10-01

Fiber optic sensor embedded in textiles has been a new direction of researching smart wearable technology. Pulse signal which is generated by heart beat contains vast amounts of physio-pathological information about the cardiovascular system. Therefore, the research for textile-based fiber optic sensor which can detect pulse wave has far-reaching effects on early discovery and timely treatment of cardiovascular diseases. A novel wavelength demodulation method based on photonic crystal fiber (PCF) modal interference filter is proposed for the purpose of developing FBG pulse wave sensing system embedded in smart clothing. The mechanism of the PCF modal interference and the principle of wavelength demodulation based on In-line Mach-Zehnder interferometer (In-line MZI) are analyzed in theory. The fabricated PCF modal interferometer has the advantages of good repeatability and low temperature sensitivity of 3.5pm/°C from 25°C to 60°C. The designed demodulation system can achieve linear demodulation in the range of 2nm, with the wavelength resolution of 2.2pm and the wavelength sensitivity of 0.055nm-1. The actual experiments' result indicates that the pulse wave can be well detected by this demodulation method, which is in accordance with the commercial demodulation instrument (SM130) and more sensitive than the traditional piezoelectric pulse sensor. This demodulation method provides important references for the research of smart clothing based on fiber grating sensor embedded in textiles and accelerates the developments of wearable fiber optic sensors technology.

Enhanced shock wave generation via pre-breakdown acceleration using water electrolysis in negative streamer pulsed spark discharges

NASA Astrophysics Data System (ADS)

Lee, Kern; Chung, Kyoung-Jae; Hwang, Y. S.

2018-03-01

This paper presents a method for enhancement of shock waves generated from underwater pulsed spark discharges with negative (anode-directed) subsonic streamers, for which the pre-breakdown process is accelerated by preconditioning a gap with water electrolysis. Hydrogen microbubbles are produced at the cathode by the electrolysis and move towards the anode during the preconditioning phase. The numbers and spatial distributions of the microbubbles vary with the amplitude and duration of each preconditioning pulse. Under our experimental conditions, the optimum pulse duration is determined to be ˜250 ms at a pulse voltage of 400 V, where the buoyancy force overwhelms the electric force and causes the microbubbles to be swept out from the water gap. When a high-voltage pulse is applied to the gap just after the preconditioning pulse, the pre-breakdown process is significantly accelerated in the presence of the microbubbles. At the optimum preconditioning pulse duration, the average breakdown delay is reduced by 87% and, more importantly, the energy consumed during the pre-breakdown period decreases by 83%. This reduced energy consumption during the pre-breakdown period, when combined with the morphological advantages of negative streamers, such as thicker and longer stalks, leads to a significant improvement in the measured peak pressure (˜40%) generated by the underwater pulsed spark discharge. This acceleration of pre-breakdown using electrolysis overcomes the biggest drawback of negative subsonic discharges, which is slow vapor bubble formation due to screening effects, and thus enhances the efficiency of the shock wave generation process using pulsed spark discharges in water.

Characteristic Extraction of Mental Disease Patients by Nonlinear Analysis of Plethysmograms

NASA Astrophysics Data System (ADS)

Hu, Yuyu; Wang, Wenbiao; Suzuki, Takashi; Oyama-Higa, Mayumi

2011-06-01

We measured the pulse waves of 196 mentally ill patients and 113 healthy students. Using heartbeat changes, we calculated the values of their sympathetic nerves, parasympathetic nerves, and autonomic nerve balance. In addition, we calculated the largest Lyapunov exponents (LLE) by non-linear analysis of plethysmograms. Values were analyzed by group. The results revealed a significant relationship between LLE and the autonomic nerve balance. The sympathetic nerve values in the patient group were significantly higher than those in the student group, whereas the LLE values were significantly lower. Furthermore, we illustrated the dynamic change in the results for single participants over several testing times. The measurement of pulse waves is easy and economical and does not put a strain on the subject. Additionally, these values can provide information that is more accurate than medical examination obtained from an interview. Our study contributed to the existing methodology in this field, and future data collection and measurement will be carried out. We hope that our study will be useful for neurologists and psychotherapists in their detection and treatment of mental illness.

Performance Analysis of a Static Synchronous Compensator (STATCOM)

NASA Astrophysics Data System (ADS)

Kambey, M. M.; Ticoh, J. D.

2018-02-01

Reactive power and voltage are some of the problems in electric power supply and A Gate Turn Off (GTO) Static Synchronous Compensator (STATCOM) is one of the type of FACTS with shunt which can supply variable reactive power and regulate the voltage of the bus where it is connected. This study only discuss about the performance characteristic of the three phase six-pulse STATCOM by analysing the current wave flowing through DC Capacitor which depend on switching current and capacitor voltage wave. Simulation methods used in this research is started with a mathematical analysis of the ac current, dc voltage and current equations that pass STATCOM from a literature. The result shows the presence of the capacitor voltage ripple also alters the ac current waveform, even though the errors to be not very significant and the constraint of the symmetry circuit is valid if the source voltages have no zero sequence components and the impedances in all the three phases are identical. There for to improve STATCOM performance it is necessary to use multi-pulse 12, 24, 36, 48 or more, and/or with a multilevel converter.

Rapid testing of pulse transformers

NASA Technical Reports Server (NTRS)

Grillo, J.

1980-01-01

Quality-control testing of pulse transformers is speeded up by method for determining rise time and droop. Instead of using oscilloscope and square-wave generator to measure these characteristics directly, method uses voltmeter and sine-wave generator to measure them indirectly in about one-tenth time. Droop and rise time are determined by measuring input/output voltage ratio at just four frequencies.

Relativistic Eulerian Vlasov simulations of the amplification of seed pulses by Brillouin backscattering in plasmas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shoucri, M., E-mail: Shoucri.Magdi@ireq.ca; Matte, J.-P.; Vidal, F.

We apply an Eulerian Vlasov code to study the amplification by Brillouin scattering of a short seed laser pulse by a long pump laser pulse in an underdense plasma. The stimulated Brillouin backscattering interaction is the coupling of the pump and seed electromagnetic waves propagating in opposite directions, and the ion plasma wave. The code solves the one-dimensional relativistic Vlasov-Maxwell set of equations. Large amplitude ion waves are generated. In the simulations we present, the density plateau of the plasma is n{sub e}=0.3 n{sub c} (n{sub c} is the critical density), which excludes spurious stimulated Raman scattering amplification (which can occurmore » only if n{sub e}« less

A theoretical analysis of anatomical and functional intestinal slow wave re-entry.

PubMed

Du, Peng; O'Grady, Gregory; Cheng, Leo K

2017-07-21

Intestinal bioelectrical slow waves are a key regulator of intestinal motility. Peripheral pacemakers, ectopic initiations and sustained periods of re-entrant activities have all been experimentally observed to be important factors in setting the frequency of intestinal slow waves, but the tissue-level mechanisms underpinning these activities are unclear. This theoretical analysis aimed to define the initiation, maintenance, and termination criteria of two classes of intestinal re-entrant activities: anatomical re-entry and functional re-entry. Anatomical re-entry was modeled in a three-dimensional (3D) cylindrical model, and functional rotor was modeled in a 2D rectangle model. A single-pulse stimulus was used to invoke an anatomical re-entry and a prolonged refractory block was used to invoke the rotor. In both cases, the simulated re-entrant activities operated at frequencies above the baseline entrainment frequency. The anatomical re-entry simulation results demonstrated that a temporary functional refractory block would be required to initiate the re-entrant activity in a single direction around the cylindrical model. The rotor could be terminated by a single-pulse stimulus delivered around the core of the rotor. In conclusion, the simulation results provide the following new insights into the mechanisms of intestinal re-entry: (i) anatomical re-entry is only maintained within a specific range of velocities, outside of which the re-entrant activities become either an ectopic activity or simultaneous activations of the intestinal wall; (ii) a maintained rotor entrained slow waves faster in the antegrade direction than in the retrograde direction. Simulations are shown to be a valuable tool for achieving novel insights into the mechanisms of intestinal slow wave dysrhythmia. Copyright © 2017 Elsevier Ltd. All rights reserved.

Detonation wave compression in gas turbines

NASA Technical Reports Server (NTRS)

Wortman, A.

1986-01-01

A study was made of the concept of augmenting the performance of low pressure ratio gas turbines by detonation wave compression of part of the flow. The concept exploits the constant volume heat release of detonation waves to increase the efficiency of the Brayton cycle. In the models studied, a fraction of the compressor output was channeled into detonation ducts where it was processed by transient transverse detonation waves. Gas dynamic studies determined the maximum cycling frequency of detonation ducts, proved that upstream propagation of pressure pulses represented no problems and determined the variations of detonation duct output with time. Mixing and wave compression were used to recombine the combustor and detonation duct flows and a concept for a spiral collector to further smooth the pressure and temperature pulses was presented as an optional component. The best performance was obtained with a single firing of the ducts so that the flow could be re-established before the next detonation was initiated. At the optimum conditions of maximum frequency of the detonation ducts, the gas turbine efficiency was found to be 45 percent while that of a corresponding pressure ratio 5 conventional gas turbine was only 26%. Comparable improvements in specific fuel consumption data were found for gas turbines operating as jet engines, turbofans, and shaft output machines. Direct use of the detonation duct output for jet propulsion proved unsatisfactory. Careful analysis of the models of the fluid flow phenomena led to the conclusion that even more elaborate calculations would not diminish the uncertainties in the analysis of the system. Feasibility of the concept to work as an engine now requires validation in an engineering laboratory experiment.

Central Arterial Function Measured by Non-invasive Pulse Wave Analysis is Abnormal in Patients with Duchenne Muscular Dystrophy.

PubMed

Ryan, Thomas D; Parent, John J; Gao, Zhiqian; Khoury, Philip R; Dupont, Elizabeth; Smith, Jennifer N; Wong, Brenda; Urbina, Elaine M; Jefferies, John L

2017-08-01

Duchenne muscular dystrophy (DMD) is an X-linked recessive disorder caused by mutation of dystrophin. Cardiovascular involvement includes dilated cardiomyopathy. Non-invasive assessment of vascular function has not been evaluated in DMD. We hypothesize arterial wave reflection is abnormal in patients with DMD. Pulse wave analysis was performed on DMD patients with a SphygmoCor SCOR-PVx System to determine central blood pressure and augmentation index (AIx) as an assessment of arterial wave reflection. Results were compared to a control group. A total of 43 patients with DMD were enrolled, and compared to 43 normal controls. Central systolic blood pressure was lower, while both AIx-75 (7.8 ± 9.6% vs. 2.1 ± 10.4%, p 0.01, DMD vs. normal) and AIx-not corrected (16.8 ± 10.1% vs. -3.6 ± 10.9, p < 0.001, DMD vs. normal) were higher in the DMD compared to control. Using multivariable linear regression model, the variables found to have a significant effect on AIx-not corrected included diagnosis of DMD, height, and heart rate (r 2  = 0.257). The current data suggest that, despite lower central systolic blood pressure, patients with DMD have higher wave reflection when compared to normal controls, which may represent increased arterial stiffness. Overall there appears to be no effect on ventricular systolic function, however the long-term consequence in this group is unknown. Further study is required to determine the mechanism of these differences, which may be related to the effects of systemic steroids or the role of dystrophin in vascular function.

Induction of subterahertz surface waves on a metal wire by intense laser interaction with a foil

NASA Astrophysics Data System (ADS)

Teramoto, Kensuke; Inoue, Shunsuke; Tokita, Shigeki; Yasuhara, Ryo; Nakamiya, Yoshihide; Nagashima, Takeshi; Mori, Kazuaki; Hashida, Masaki; Sakabe, Shuji

2018-02-01

We have demonstrated that a pulsed electromagnetic wave (Sommerfeld wave) of subterahertz frequency and 11-MV/m field strength can be induced on a metal wire by the interaction of an intense femtosecond laser pule with an adjacent metal foil at a laser intensity of 8.5 × 1018W /c m2 . The polarity of the electric field of this surface wave is opposite to that obtained by the direct interaction of the laser with the wire. Numerical simulations suggest that an electromagnetic wave associated with electron emission from the foil induces the surface wave. A tungsten wire is placed normal to an aluminum foil with a gap so that the wire is not irradiated and damaged by the laser pulse, thus making it possible to generate surface waves on the wire repeatedly.