Energetic mid-IR femtosecond pulse generation by self-defocusing soliton-induced dispersive waves in a bulk quadratic nonlinear crystal.

PubMed

Zhou, Binbin; Guo, Hairun; Bache, Morten

2015-03-09

Generating energetic femtosecond mid-IR pulses is crucial for ultrafast spectroscopy, and currently relies on parametric processes that, while efficient, are also complex. Here we experimentally show a simple alternative that uses a single pump wavelength without any pump synchronization and without critical phase-matching requirements. Pumping a bulk quadratic nonlinear crystal (unpoled LiNbO(3) cut for noncritical phase-mismatched interaction) with sub-mJ near-IR 50-fs pulses, tunable and broadband (∼ 1,000 cm(-1)) mid-IR pulses around 3.0 μm are generated with excellent spatio-temporal pulse quality, having up to 10.5 μJ energy (6.3% conversion). The mid-IR pulses are dispersive waves phase-matched to near-IR self-defocusing solitons created by the induced self-defocusing cascaded nonlinearity. This process is filament-free and the input pulse energy can therefore be scaled arbitrarily by using large-aperture crystals. The technique can readily be implemented with other crystals and laser wavelengths, and can therefore potentially replace current ultrafast frequency-conversion processes to the mid-IR.

On the importance of electron impact processes in excimer-pumped alkali laser-induced plasmas

DOE PAGES

Markosyan, Aram H.

2017-10-18

We present that the excimer-pumped alkali laser (XPAL) system has recently been demonstrated in several different mixtures of alkali vapor and rare gas. Without special preventive measures, plasma formation during operation of XPAL is unavoidable. Some recent advancements in the availability of reliable data for electron impact collisions with atoms and molecules have enabled development of a complete reaction mechanism to investigate XPAL-induced plasmas. Here, we report on pathways leading to plasma formation in an Ar/C 2H 6/CsAr/C2H6/Cs XPAL sustained at different cell temperatures. We find that depending on the operating conditions, the contribution of electron impact processes can bemore » as little as bringing the excitation of Cs(P 2) states to higher level Cs** states, and can be as high as bringing Cs(P 2) excited states to a full ionization. Increasing the input pumping power or cell temperature, or decreasing the C 2H 6 mole fraction leads to electron impact processes dominating in plasma formation over the energy pooling mechanisms previously reported in literature.« less

Polyamines cause plasma membrane depolarization, activate Ca2+-, and modulate H+-ATPase pump activity in pea roots.

PubMed

Pottosin, Igor; Velarde-Buendía, Ana María; Bose, Jayakumar; Fuglsang, Anja T; Shabala, Sergey

2014-06-01

Polyamines regulate a variety of cation and K(+) channels, but their potential effects on cation-transporting ATPases are underexplored. In this work, noninvasive microelectrode ion flux estimation and conventional microelectrode techniques were applied to study the effects of polyamines on Ca(2+) and H(+) transport and membrane potential in pea roots. Externally applied spermine or putrescine (1mM) equally activated eosin yellow (EY)-sensitive Ca(2+) pumping across the root epidermis and caused net H(+) influx or efflux. Proton influx induced by spermine was suppressed by EY, supporting the mechanism in which Ca(2+) pump imports 2 H(+) per each exported Ca(2+). Suppression of the Ca(2+) pump by EY diminished putrescine-induced net H(+) efflux instead of increasing it. Thus, activities of Ca(2+) and H(+) pumps were coupled, likely due to the H(+)-pump inhibition by intracellular Ca(2+). Additionally, spermine but not putrescine caused a direct inhibition of H(+) pumping in isolated plasma membrane vesicles. Spermine, spermidine, and putrescine (1mM) induced membrane depolarization by 70, 50, and 35 mV, respectively. Spermine-induced depolarization was abolished by cation transport blocker Gd(3+), was insensitive to anion channels' blocker niflumate, and was dependent on external Ca(2+). Further analysis showed that uptake of polyamines but not polyamine-induced cationic (K(+)+Ca(2+)+H(+)) fluxes were a main cause of membrane depolarization. Polyamine increase is a common component of plant stress responses. Activation of Ca(2+) efflux by polyamines and contrasting effects of polyamines on net H(+) fluxes and membrane potential can contribute to Ca(2+) signalling and modulate a variety of transport processes across the plasma membrane under stress. © The Author 2014. Published by Oxford University Press on behalf of the Society for Experimental Biology. All rights reserved. For permissions, please email: journals.permissions@oup.com.

The Sponge Pump: The Role of Current Induced Flow in the Design of the Sponge Body Plan

PubMed Central

Leys, Sally P.; Yahel, Gitai; Reidenbach, Matthew A.; Tunnicliffe, Verena; Shavit, Uri; Reiswig, Henry M.

2011-01-01

Sponges are suspension feeders that use flagellated collar-cells (choanocytes) to actively filter a volume of water equivalent to many times their body volume each hour. Flow through sponges is thought to be enhanced by ambient current, which induces a pressure gradient across the sponge wall, but the underlying mechanism is still unknown. Studies of sponge filtration have estimated the energetic cost of pumping to be <1% of its total metabolism implying there is little adaptive value to reducing the cost of pumping by using “passive” flow induced by the ambient current. We quantified the pumping activity and respiration of the glass sponge Aphrocallistes vastus at a 150 m deep reef in situ and in a flow flume; we also modeled the glass sponge filtration system from measurements of the aquiferous system. Excurrent flow from the sponge osculum measured in situ and in the flume were positively correlated (r>0.75) with the ambient current velocity. During short bursts of high ambient current the sponges filtered two-thirds of the total volume of water they processed daily. Our model indicates that the head loss across the sponge collar filter is 10 times higher than previously estimated. The difference is due to the resistance created by a fine protein mesh that lines the collar, which demosponges also have, but was so far overlooked. Applying our model to the in situ measurements indicates that even modest pumping rates require an energetic expenditure of at least 28% of the total in situ respiration. We suggest that due to the high cost of pumping, current-induced flow is highly beneficial but may occur only in thin walled sponges living in high flow environments. Our results call for a new look at the mechanisms underlying current-induced flow and for reevaluation of the cost of biological pumping and its evolutionary role, especially in sponges. PMID:22180779

Impact of mixing chemically heterogeneous groundwaters on the sustainability of an open-loop groundwater heat pump

NASA Astrophysics Data System (ADS)

Burté, L.; Farasin, J.; Cravotta, C., III; Gerard, M. F.; Cotiche Baranger, C.; Aquilina, L.; Le Borgne, T.

2017-12-01

Geothermal systems using shallow aquifers are commonly used for heating and cooling. The sustainability of these systems can be severely impacted by the occurrence of clogging process. The geothermal loop operation (including pumping of groundwater, filtering and heat extraction through exchangers and cooled water injection) can lead to an unexpected biogeochemical reactivity and scaling formation that can ultimately lead to the shutdown of the geothermal doublet. Here, we report the results of investigations carried out on a shallow geothermal doublet (< 40 m depth) affected by rapid clogging processes linked to iron and manganese oxidation. Using a reactive transport model, we determine the parameters controlling clogging. To characterize the biogeochemical processes induced by the operation of the production well, we combined hydrodynamic measurements by flowmeter and in-situ chemical depth profiles. We thus investigated the chemical heterogeneity into the pumping well as a function of the operating conditions (static or dynamic). Hydrochemical data collected at the pumping well showed that groundwater was chemically heterogeneous long the 11 meters well screen. While the aquifer was dominantly oxic, a localized inflow of anoxic water was detected and evaluated to produce about 40% of the total flow . The mixture of chemically heterogeneous water induced by pumping lead to the oxidation of reductive species and thus to the formation of biogenic precipitates responsible for clogging. The impact of pumping waters of different redox potential and chemical characteristics was quantified by numerical modeling using PHREEQC. These results shows that natural chemical heterogeneity can occur at a small scale in heterogeneous aquifers and highlight the importance of their characterization during the production well testing and the geothermal loop operation in order to take preventive measures to avoid clogging.

How reduced vacuum pumping capability in a coating chamber affects the laser damage resistance of HfO 2/SiO 2 antireflection and high reflection coatings.

DOE PAGES

Field, Ella Suzanne; Bellum, John Curtis; Kletecka, Damon E.

2016-06-01

Optical coatings with the highest laser damage thresholds rely on clean conditions in the vacuum chamber during the coating deposition process. A low base pressure in the coating chamber, as well as the ability of the vacuum system to maintain the required pressure during deposition, are important aspects of limiting the amount of defects in an optical coating that could induce laser damage. Our large optics coating chamber at Sandia National Laboratories normally relies on three cryo pumps to maintain low pressures for e-beam coating processes. However, on occasion, one or more of the cryo pumps have been out ofmore » commission. In light of this circumstance, we explored how deposition under compromised vacuum conditions resulting from the use of only one or two cryo pumps affects the laser-induced damage thresholds of optical coatings. Finally, the coatings of this study consist of HfO 2 and SiO 2 layer materials and include antireflection coatings for 527 nm at normal incidence, and high reflection coatings for 527 nm, 45⁰ angle of incidence (AOI), in P-polarization (P-pol).« less

How reduced vacuum pumping capability in a coating chamber affects the laser damage resistance of HfO 2/SiO 2 antireflection and high-reflection coatings

DOE PAGES

Field, Ella S.; Bellum, John C.; Kletecka, Damon E.

2016-07-15

Here, optical coatings with the highest laser damage thresholds rely on clean conditions in the vacuum chamber during the coating deposition process. A low-base pressure in the coating chamber, as well as the ability of the vacuum system to maintain the required pressure during deposition, are important aspects of limiting the amount of defects in an optical coating that could induce laser damage. Our large optics coating chamber at Sandia National Laboratories normally relies on three cryo pumps to maintain low pressures for e-beam coating processes. However, on occasion, one or more of the cryo pumps have been out ofmore » commission. In light of this circumstance, we explored how deposition under compromised vacuum conditions resulting from the use of only one or two cryo pumps affects the laser-induced damage thresholds of optical coatings. The coatings of this study consist of HfO 2 and SiO 2 layer materials and include antireflection coatings for 527 nm at normal incidence and high-reflection coatings for 527 nm at 45-deg angle of incidence in P-polarization.« less

Pump RIN-induced impairments in unrepeatered transmission systems using distributed Raman amplifier.

PubMed

Cheng, Jingchi; Tang, Ming; Lau, Alan Pak Tao; Lu, Chao; Wang, Liang; Dong, Zhenhua; Bilal, Syed Muhammad; Fu, Songnian; Shum, Perry Ping; Liu, Deming

2015-05-04

High spectral efficiency modulation format based unrepeatered transmission systems using distributed Raman amplifier (DRA) have attracted much attention recently. To enhance the reach and optimize system performance, careful design of DRA is required based on the analysis of various types of impairments and their balance. In this paper, we study various pump RIN induced distortions on high spectral efficiency modulation formats. The vector theory of both 1st and higher-order stimulated Raman scattering (SRS) effect using Jones-matrix formalism is presented. The pump RIN will induce three types of distortion on high spectral efficiency signals: intensity noise stemming from SRS, phase noise stemming from cross phase modulation (XPM), and polarization crosstalk stemming from cross polarization modulation (XPolM). An analytical model for the statistical property of relative phase noise (RPN) in higher order DRA without dealing with complex vector theory is derived. The impact of pump RIN induced impairments are analyzed in polarization-multiplexed (PM)-QPSK and PM-16QAM-based unrepeatered systems simulations using 1st, 2nd and 3rd-order forward pumped Raman amplifier. It is shown that at realistic RIN levels, negligible impairments will be induced to PM-QPSK signals in 1st and 2nd order DRA, while non-negligible impairments will occur in 3rd order case. PM-16QAM signals suffer more penalties compared to PM-QPSK with the same on-off gain where both 2nd and 3rd order DRA will cause non-negligible performance degradations. We also investigate the performance of digital signal processing (DSP) algorithms to mitigate such impairments.

Transformation of EIA to EIT by incoherent pumping of the 85Rb D1 line

NASA Astrophysics Data System (ADS)

Yu, Hoon; Kim, Jung Dong; Jung, Tae Young; Kim, Jung Bog

2012-10-01

We have observed a transformation from electromagnetically-induced absorption (EIA) to electromagnetically induced transparency (EIT) in open systems of the 85Rb D1 line by adding an incoherent optical pumping laser. This result raises a new question about recent theoretical work which does not address the degree of open. The pump beam only plays a role in transferring atoms by a spontaneous transition into the interacting system for EIT observation, which is an incoherent process. The dependence of the absorption spectra on the intensity and the polarization of each laser beam were observed. We have found the same tendencies in all transitions except the F = 2 ↔ F' = 3 transition of the 85Rb D1 line, which is the system that almost satisfies conventional EIA conditions.

Dynamic behavior of pump light radiation induced photo-bleaching effect on BAC-Si in bismuth/erbium co-doped optical fibers

NASA Astrophysics Data System (ADS)

Ding, Mingjie; Luo, Yanhua; Wen, Jianxiang; Peng, Gang-Ding

2018-02-01

Ultra-wide emission in bismuth doped optical fiber has been extremely studied for the development of the laser and amplifier working at near infrared band. In our homemade bismuth/erbium co-doped optical fiber, bismuth active center associated with silica (BAC-Si) has been found that when pumping at its resonant wavelength at 830 nm the NIR emission could be partially bleached. In addition, a self-recovery process has been observed at room temperature. However, the exact mechanism is still unclear. In this work, we have investigated the photo-bleaching effect on the BAC-Si via the pump power, pump wavelength and temperature dependence. Based on analyzing the result using stretched exponential function, it shows that the bleaching effect on BAC-Si has a strong link with the excitation process of Bi ion in BAC-Si. A potential energy curve model is used to illustrate the BAC-Si photo-bleaching process.

Autotrophic denitrification supported by biotite dissolution in crystalline aquifers: (2) transient mixing and denitrification dynamic during long-term pumping.

PubMed

Roques, Clément; Aquilina, Luc; Boisson, Alexandre; Vergnaud-Ayraud, Virginie; Labasque, Thierry; Longuevergne, Laurent; Laurencelle, Marc; Dufresne, Alexis; de Dreuzy, Jean-Raynald; Pauwels, Hélène; Bour, Olivier

2018-04-01

We investigated the mixing and dynamic of denitrification processes induced by long-term pumping in the crystalline aquifer of Ploemeur (Brittany, France). Hydrological and geochemical parameters have been continuously recorded over 15 boreholes in 5km 2 on a 25-year period. This extensive spatial and temporal monitoring of conservative as well as reactive compounds is a key opportunity to identify aquifer-scale transport and reactive processes in crystalline aquifers. Time series analysis of the conservative elements recorded at the pumped well were used to determine mixing fractions from different compartments of the aquifer on the basis of a Principal Component Analysis approach coupled with an end-member mixing analysis. We could reveal that pumping thus induces a thorough reorganization of fluxes known as capture, favoring infiltration and vertical fluxes in the recharge zone, and upwelling of deep and distant water at long-term time scales. These mixing fractions were then used to quantify the extent of denitrification linked to pumping. Based on the results from batch experiments described in a companion paper, our computations revealed that i) autotrophic denitrification processes are dominant in this context where carbon sources are limited, that ii) nitrate reduction does not only come from the oxidation of pyrite as classically described in previous studies analyzing denitrification processes in similar contexts, and that iii) biotite plays a critical role in sustaining the nitrate reduction process. Both nitrate reduction, sulfate production as well as fluor release ratios support the hypothesis that biotite plays a key role of electron donor in this context. The batch-to-site similarities support biotite availability and the role by bacterial communities as key controls of nitrate removal in such crystalline aquifers. However, the long term data monitoring also indicates that mixing and reactive processes evolve extremely slowly at the scale of the decade. Copyright © 2017 Elsevier B.V. All rights reserved.

Stimulated parametric emission microscopy.

PubMed

Isobe, Keisuke; Kataoka, Shogo; Murase, Rena; Watanabe, Wataru; Higashi, Tsunehito; Kawakami, Shigeki; Matsunaga, Sachihiro; Fukui, Kiichi; Itoh, Kazuyoshi

2006-01-23

We propose a novel microscopy technique based on the four-wave mixing (FWM) process that is enhanced by two-photon electronic resonance induced by a pump pulse along with stimulated emission induced by a dump pulse. A Ti:sapphire laser and an optical parametric oscillator are used as light sources for the pump and dump pulses, respectively. We demonstrate that our proposed FWM technique can be used to obtain a one-dimensional image of ethanol-thinned Coumarin 120 solution sandwiched between a hole-slide glass and a cover slip, and a two-dimensional image of a leaf of Camellia sinensis.

Molecular alignment effect on the photoassociation process via a pump-dump scheme.

PubMed

Wang, Bin-Bin; Han, Yong-Chang; Cong, Shu-Lin

2015-09-07

The photoassociation processes via the pump-dump scheme for the heternuclear (Na + H → NaH) and the homonuclear (Na + Na → Na2) molecular systems are studied, respectively, using the time-dependent quantum wavepacket method. For both systems, the initial atom pair in the continuum of the ground electronic state (X(1)Σ(+)) is associated into the molecule in the bound states of the excited state (A(1)Σ(+)) by the pump pulse. Then driven by a time-delayed dumping pulse, the prepared excited-state molecule can be transferred to the bound states of the ground electronic state. It is found that the pump process can induce a superposition of the rovibrational levels |v, j〉 on the excited state, which can lead to the field-free alignment of the excited-state molecule. The molecular alignment can affect the dumping process by varying the effective coupling intensity between the two electronic states or by varying the population transfer pathways. As a result, the final population transferred to the bound states of the ground electronic state varies periodically with the delay time of the dumping pulse.

Molecular alignment effect on the photoassociation process via a pump-dump scheme

NASA Astrophysics Data System (ADS)

Wang, Bin-Bin; Han, Yong-Chang; Cong, Shu-Lin

2015-09-01

The photoassociation processes via the pump-dump scheme for the heternuclear (Na + H → NaH) and the homonuclear (Na + Na → Na2) molecular systems are studied, respectively, using the time-dependent quantum wavepacket method. For both systems, the initial atom pair in the continuum of the ground electronic state (X1Σ+) is associated into the molecule in the bound states of the excited state (A1Σ+) by the pump pulse. Then driven by a time-delayed dumping pulse, the prepared excited-state molecule can be transferred to the bound states of the ground electronic state. It is found that the pump process can induce a superposition of the rovibrational levels |v, j> on the excited state, which can lead to the field-free alignment of the excited-state molecule. The molecular alignment can affect the dumping process by varying the effective coupling intensity between the two electronic states or by varying the population transfer pathways. As a result, the final population transferred to the bound states of the ground electronic state varies periodically with the delay time of the dumping pulse.

Modeling of THz Lasers Based on Intersubband Transitions in Semiconductor Quantum Wells

NASA Technical Reports Server (NTRS)

Liu, Ansheng; Woo, Alex C. (Technical Monitor)

1999-01-01

In semiconductor quantum well structures, the intersubband energy separation can be adjusted to the terahertz (THz) frequency range by changing the well width and material combinations. The electronic and optical properties of these nanostructures can also be controlled by an applied dc electric field. These unique features lead to a large frequency tunability of the quantum well devices. In the on-going project of modeling of the THz lasers, we investigate the possibility of using optical pumping to generate THz radiation based on intersubband transitions in semiconductor quantum wells. We choose the optical pumping because in the electric current injection it is difficult to realize population inversion in the THz frequency range due to the small intersubband separation (4-40 meV). We considered both small conduction band offset (GaAs/AlGaAs) and large band offset (InGaAs/AlAsSb) quantum well structures. For GaAs/AlGaAs quantum wells, mid-infrared C02 lasers are used as pumping sources. For InGaAs/AlAsSb quantum wells, the resonant intersubband transitions can be excited by the near-infrared diode lasers. For three- and four-subband quantum wells, we solve the pumpfield-induced nonequilibrium distribution function for each subband of the quantum well system from a set of rate equations that include both intrasubband and intersubband relaxation processes. Taking into account the coherent interactions between pump and THz (signal) waves, we calculate the optical gain for the THz field. The gain arising from population inversion and stimulated Raman processes is calculated in a unified manner. A graph shows the calculated THz gain spectra for three-subband GaAs/AlGaAs quantum wells. We see that the coherent pump and signal wave interactions contribute significantly to the gain. The pump intensity dependence of the THz gain is also studied. The calculated results are shown. Because of the optical Stark effect and pump-induced population redistribution, the maximum THz gain saturates at larger pump intensities.

Molecular alignment effect on the photoassociation process via a pump-dump scheme

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Bin-Bin; Han, Yong-Chang, E-mail: ychan@dlut.edu.cn; Cong, Shu-Lin

The photoassociation processes via the pump-dump scheme for the heternuclear (Na + H → NaH) and the homonuclear (Na + Na → Na{sub 2}) molecular systems are studied, respectively, using the time-dependent quantum wavepacket method. For both systems, the initial atom pair in the continuum of the ground electronic state (X{sup 1}Σ{sup +}) is associated into the molecule in the bound states of the excited state (A{sup 1}Σ{sup +}) by the pump pulse. Then driven by a time-delayed dumping pulse, the prepared excited-state molecule can be transferred to the bound states of the ground electronic state. It is found thatmore » the pump process can induce a superposition of the rovibrational levels |v, j〉 on the excited state, which can lead to the field-free alignment of the excited-state molecule. The molecular alignment can affect the dumping process by varying the effective coupling intensity between the two electronic states or by varying the population transfer pathways. As a result, the final population transferred to the bound states of the ground electronic state varies periodically with the delay time of the dumping pulse.« less

ac electroosmotic pumping induced by noncontact external electrodes.

PubMed

Wang, Shau-Chun; Chen, Hsiao-Ping; Chang, Hsueh-Chia

2007-09-21

Electroosmotic (EO) pumps based on dc electroosmosis is plagued by bubble generation and other electrochemical reactions at the electrodes at voltages beyond 1 V for electrolytes. These disadvantages limit their throughput and offset their portability advantage over mechanical syringe or pneumatic pumps. ac electroosmotic pumps at high frequency (>100 kHz) circumvent the bubble problem by inducing polarization and slip velocity on embedded electrodes,1 but they require complex electrode designs to produce a net flow. We report a new high-throughput ac EO pump design based on induced-polarization on the entire channel surface instead of just on the electrodes. Like dc EO pumps, our pump electrodes are outside of the load section and form a cm-long pump unit consisting of three circular reservoirs (3 mm in diameter) connected by a 1x1 mm channel. The field-induced polarization can produce an effective Zeta potential exceeding 1 V and an ac slip velocity estimated as 1 mmsec or higher, both one order of magnitude higher than earlier dc and ac pumps, giving rise to a maximum throughput of 1 mulsec. Polarization over the entire channel surface, quadratic scaling with respect to the field and high voltage at high frequency without electrode bubble generation are the reasons why the current pump is superior to earlier dc and ac EO pumps.

NOLM-based all-optical 40 Gbit/s format conversion through sum-frequency generation (SFG) in a PPLN waveguide

NASA Astrophysics Data System (ADS)

Wang, Jian; Sun, Junqiang

2005-11-01

A novel all-optical format conversion scheme from NRZ to RZ based on sum-frequency generation (SFG) in a periodically poled LiNbO 3 (PPLN) waveguide is proposed, using a nonlinear optical loop mirror (NOLM). The conversion mechanism relies on the combination of attenuation and nonlinear phase shift induced on the clockwise signal field during the SFG process. The SFG between pump, and co- and counter- propagating signals in the PPLN waveguide are numerically studied, showing that counter-propagating SFG can be ignored when quasi-phase matching (QPM) for SFG during co-propagating interaction. The nonlinear phase shift induced on the clockwise signal field is analyzed in detail, showing that it is more effective to yield large values for nonlinear phase shift when appropriately phase mismatched for the SFG process. Two tuning schemes are proposed depend on whether the sum-frequency wavelength is variable or fixed. It is found that the latter has a rather wide 3dB signal conversion bandwidth approximately 154nm. Finally, the influence of reversible process of SFG is discussed and the optimum arrangement of pump and signal peak powers is theoretically demonstrated. The result shows that proper power arrangement, pump width, and waveguide length are necessary for achieving a good conversion effect.

Observation of enhanced thermal lensing due to near-Gaussian pump energy deposition in a laser-diode side-pumped Nd:YAG laser

NASA Technical Reports Server (NTRS)

Welford, David; Rines, David M.; Dinerman, Bradley J.; Martinsen, Robert

1992-01-01

The authors report operation of a laser-diode side-pumped Nd:YAG laser with a novel pumping geometry that ensures efficient conversion of pump energy into the TEM00 mode. Significant enhancement of thermally induced lensing due to the near-Gaussian energy deposition profile of the pump radiation was observed. An induced lens of approximately 3.2-m focal length was measured at average incident pump powers of only 3.2 W (corresponding to a 0.6 W heat load).

Rotary blood pump

NASA Technical Reports Server (NTRS)

Benkowski, Robert J. (Inventor); Kiris, Cetin (Inventor); Kwak, Dochan (Inventor); Rosenbaum, Bernard J. (Inventor); Bacak, James W. (Inventor); DeBakey, Michael E. (Inventor)

1999-01-01

A blood pump that comprises a pump housing having a blood flow path therethrough, a blood inlet, and a blood outlet; a stator mounted to the pump housing, the stator having a stator field winding for producing a stator magnetic field; a flow straightener located within the pump housing, and comprising a flow straightener hub and at least one flow straightener blade attached to the flow straightener hub; a rotor mounted within the pump housing for rotation in response to the stator magnetic field, the rotor comprising an inducer and an impeller; the inducer being located downstream of the flow straightener, and comprising an inducer hub and at least one inducer blade attached to the inducer hub; the impeller being located downstream of the inducer, and comprising an impeller hub and at least one impeller blade attached to the impeller hub; and preferably also comprising a diffuser downstream of the impeller, the diffuser comprising a diffuser hub and at least one diffuser blade. Blood flow stagnation and clot formation within the pump are minimized by, among other things, providing the inducer hub with a diameter greater than the diameter of the flow straightener hub; by optimizing the axial spacing between the flow straightener hub and the inducer hub, and between the impeller hub and the diffuser hub; by optimizing the inlet angle of the diffuser blades; and by providing fillets or curved transitions between the upstream end of the inducer hub and the shaft mounted therein, and between the impeller hub and the shaft mounted therein.

Quantum pump effect induced by a linearly polarized microwave in a two-dimensional electron gas.

PubMed

Song, Juntao; Liu, Haiwen; Jiang, Hua

2012-05-30

A quantum pump effect is predicted in an ideal homogeneous two-dimensional electron gas (2DEG) that is normally irradiated by linearly polarized microwaves (MW). Without considering effects from spin-orbital coupling or the magnetic field, it is found that a polarized MW can continuously pump electrons from the longitudinal to the transverse direction, or from the transverse to the longitudinal direction, in the central irradiated region. The large pump current is obtained for both the low frequency limit and the high frequency case. Its magnitude depends on sample properties such as the size of the radiated region, the power and frequency of the MW, etc. Through the calculated results, the pump current should be attributed to the dominant photon-assisted tunneling processes as well as the asymmetry of the electron density of states with respect to the Fermi energy.

Femtosecond laser pulse induced phase transition of Cr-doped Sb2Te1 films studied with a pump-probe system

NASA Astrophysics Data System (ADS)

Jiang, Minghui; Wang, Qing; Lei, Kai; Wang, Yang; Liu, Bo; Song, Zhitang

2016-10-01

The Femtosecond laser pulse induced phase transition dynamics of Cr-doped Sb2Te1 films was studied by real-time reflectivity measurements with a pump-probe system. It was found that crystallization of the as-deposited CrxSb2Te1 phase-change thin films exhibits a multi-stage process lasting for about 40ns.The time required for the multi-stage process seems to be not related to the contents of Cr element. The durations of the crystallization and amorphization processes are approximately the same. Doping Cr into Sb2Te1 thin film can improve its photo-thermal stability without obvious change in the crystallization rate. Optical images and image intensity cross sections are used to visualize the transformed regions. This work may provide further insight into the phase-change mechanism of CrxSb2Te1 under extra-non-equilibrium conditions and aid to develop new ultrafast phase-change memory materials.

Cavitation characteristics of a small centrifugal pump in He I and He II

NASA Technical Reports Server (NTRS)

Ludtke, P. R.; Daney, D. E.

1988-01-01

The cavitation characteristics of a small preinduced centrifugal pump operating in He I and He II over the temperature range 1.8-4.2 K are presented. The pump and close-coupled induction motor operate immersed in liquid helium. A six-blade propeller inducer and a three-blade screw inducer were both tested. With this pump configuration using either inducer, there is a tremendous difference between the cavitation characteristics of He I and He II. The net positive suction head requirements for this pump with the screw inducer could not be determined for He I, but it is less than -100 mm and, depending on flow rate, ranges between 35 and 165 mm for He II.

ac electroosmotic pumping induced by noncontact external electrodes

PubMed Central

Wang, Shau-Chun; Chen, Hsiao-Ping; Chang, Hsueh-Chia

2007-01-01

Electroosmotic (EO) pumps based on dc electroosmosis is plagued by bubble generation and other electrochemical reactions at the electrodes at voltages beyond 1 V for electrolytes. These disadvantages limit their throughput and offset their portability advantage over mechanical syringe or pneumatic pumps. ac electroosmotic pumps at high frequency (>100 kHz) circumvent the bubble problem by inducing polarization and slip velocity on embedded electrodes,1 but they require complex electrode designs to produce a net flow. We report a new high-throughput ac EO pump design based on induced-polarization on the entire channel surface instead of just on the electrodes. Like dc EO pumps, our pump electrodes are outside of the load section and form a cm-long pump unit consisting of three circular reservoirs (3 mm in diameter) connected by a 1×1 mm channel. The field-induced polarization can produce an effective Zeta potential exceeding 1 V and an ac slip velocity estimated as 1 mm∕sec or higher, both one order of magnitude higher than earlier dc and ac pumps, giving rise to a maximum throughput of 1 μl∕sec. Polarization over the entire channel surface, quadratic scaling with respect to the field and high voltage at high frequency without electrode bubble generation are the reasons why the current pump is superior to earlier dc and ac EO pumps. PMID:19693362

Deformation-induced changes in hydraulic head during ground-water withdrawal

USGS Publications Warehouse

Hsieh, Paul A.

1996-01-01

Ground-water withdrawal from a confined or semiconfined aquifer causes three-dimensional deformation in the pumped aquifer and in adjacent layers (overlying and underlying aquifers and aquitards). In response to the deformation, hydraulic head in the adjacent layers could rise or fall almost immediately after the start of pumping. This deformation-induced effect suggest that an adjacent layer undergoes horizontal compression and vertical extension when pumping begins. Hydraulic head initially drops in a region near the well and close to the pumped aquifer, but rises outside this region. Magnitude of head change varies from a few centimeters to more than 10 centimeters. Factors that influence the development of deformation-induced effects includes matrix rigidity (shear modulus), the arrangement of aquifer and aquitards, their thicknesses, and proximity to land surface. Induced rise in hydraulic head is prominent in an aquitard that extends from land surface to a shallow pumped aquifer. Induced drop in hydraulic head is likely observed close to the well in an aquifer that is separated from the pumped aquifer by a relatively thin aquitard. Induced effects might last for hours in an aquifer, but could persist for many days in an aquitard. Induced effects are eventually dissipated by fluid flow from regions of higher head to regions of lower head, and by propagation of drawdown from the pumped aquifer into adjacent layers.

High-frequency monitoring reveals nutrient sources and transport processes in an agriculture-dominated lowland water system

NASA Astrophysics Data System (ADS)

van der Grift, Bas; Broers, Hans Peter; Berendrecht, Wilbert; Rozemeijer, Joachim; Osté, Leonard; Griffioen, Jasper

2016-05-01

Many agriculture-dominated lowland water systems worldwide suffer from eutrophication caused by high nutrient loads. Insight in the hydrochemical functioning of embanked polder catchments is highly relevant for improving the water quality in such areas or for reducing export loads to downstream water bodies. This paper introduces new insights in nutrient sources and transport processes in a polder in the Netherlands situated below sea level using high-frequency monitoring technology at the outlet, where the water is pumped into a higher situated lake, combined with a low-frequency water quality monitoring programme at six locations within the drainage area. Seasonal trends and short-scale temporal dynamics in concentrations indicated that the NO3 concentration at the pumping station originated from N loss from agricultural lands. The NO3 loads appear as losses via tube drains after intensive rainfall events during the winter months due to preferential flow through the cracked clay soil. Transfer function-noise modelling of hourly NO3 concentrations reveals that a large part of the dynamics in NO3 concentrations during the winter months can be related to rainfall. The total phosphorus (TP) concentration and turbidity almost doubled during operation of the pumping station, which points to resuspension of particulate P from channel bed sediments induced by changes in water flow due to pumping. Rainfall events that caused peaks in NO3 concentrations did not results in TP concentration peaks. The rainfall induced and NO3 enriched quick interflow, may also be enriched in TP but retention of TP due to sedimentation of particulate P then results in the absence of rainfall induced TP concentration peaks. Increased TP concentrations associated with run-off events is only observed during a rainfall event at the end of a freeze-thaw cycle. All these observations suggest that the P retention potential of polder water systems is primarily due to the artificial pumping regime that buffers high flows. As the TP concentration is affected by operation of the pumping station, timing of sampling relative to the operating hours of the pumping station should be accounted for when calculating P export loads, determining trends in water quality, or when judging water quality status of polder water systems.

LH2 pump component development testing in the electric pump room at test cell C inducer no. 1

NASA Technical Reports Server (NTRS)

Andrews, F. X.; Brunner, J. J.; Kirk, K. G.; Mathews, J. P.; Nishioka, T.

1972-01-01

The characteristics of a turbine pump for use with the nuclear engine for rocket vehicles are discussed. It was determined that the pump will be a two stage centrifugal pump with both stages having backswept impellers and an inducer upstream of the first stage impeller. The test program provided demonstration of the ability of the selected design to meet the imposed requirements.

Instantaneous imaging of ozone in a gliding arc discharge using photofragmentation laser-induced fluorescence

NASA Astrophysics Data System (ADS)

Larsson, Kajsa; Hot, Dina; Gao, Jinlong; Kong, Chengdong; Li, Zhongshan; Aldén, Marcus; Bood, Joakim; Ehn, Andreas

2018-04-01

Ozone vapor, O3, is here visualized in a gliding arc discharge using photofragmentation laser-induced fluorescence. Ozone is imaged by first photodissociating the O3 molecule into an O radical and a vibrationally hot O2 fragment by a pump photon. Thereafter, the vibrationally excited O2 molecule absorbs a second (probe) photon that further transits the O2-molecule to an excited electronic state, and hence, fluorescence from the deexcitation process in the molecule can be detected. Both the photodissociation and excitation processes are achieved within one 248 nm KrF excimer laser pulse that is formed into a laser sheet and the fluorescence is imaged using an intensified CCD camera. The laser-induced signal in the vicinity of the plasma column formed by the gliding arc is confirmed to stem from O3 rather than plasma produced vibrationally hot O2. While both these products can be produced in plasmas a second laser pulse at 266 nm was utilized to separate the pump- from the probe-processes. Such arrangement allowed lifetime studies of vibrationally hot O2, which under these conditions were several orders of magnitude shorter than the lifetime of plasma-produced ozone.

Time-resolved circular dichroism: Application to the study of conformal changes in biomolecules

NASA Astrophysics Data System (ADS)

Hache, F.

2010-06-01

Circular dichroism (CD) is known to be a very sensitive probe of the conformation of molecules and biomolecules. It is therefore tempting to implement CD in a pump-probe experiment in order to measure ultrarapid conformational changes which occur in photochemical processes. We present two technical developments of such time-resolved CD experiments. The first one relies on the modulation of the probe polarization from left to right circular whereas the second one measures the pump-induced ellipticity of the probe with a Babinet-Soleil compensator. Some applications are described and extension of these techniques towards the study of elementary protein folding processes is discussed.

Generation of high powers from diode pumped chromium-3+ doped colquiriites

NASA Astrophysics Data System (ADS)

Eichenholz, Jason Matthew

1998-12-01

There is considerable interest in the area of laser diode pumped solid-state lasers. Diode pumped solid-state lasers (DPSSL) operating at high average power levels are attractive light sources for various applications such as materials processing, laser radar, and fundamental physics experiments. These laser systems have become more commonplace because of their efficiency, reliability, compactness, low relative cost, and long operational lifetimes. Induced thermal effects in the solid-state laser medium hinder the scaling of DPSSL's to higher average power levels. Therefore a deep insight into the thermo-mechanical properties of the solid state laser is crucial in order to ensure a laser design which is optimized for high average power operation. A comprehensive study of the factors that contribute to thermal loading of the colquiriites was performed. A three-dimensional thermal model has been created to determine the temperature rise inside the laser crystal. This new model calculates the temperature distribution by considering quantum defect, upconversion, and upper-state lifetime quenching as heating sources. The thermally induced lensing in end pumped Cr3+ doped LiSrAlF6, LiSrGaF6, LiSrCaAlF6, and LiCaAlF6 were experimentally measured. Several diode pumped colquiriite laser systems were assembled to quantitatively observe and identify thermally induced effects. Significant differences in each of the colquiriite materials were observed. These differences are explained by the differences in the thermo-mechanical and thermo-optical properties of the material and are explained by the theoretical thermal model.

Spin Current Noise of the Spin Seebeck Effect and Spin Pumping

NASA Astrophysics Data System (ADS)

Matsuo, M.; Ohnuma, Y.; Kato, T.; Maekawa, S.

2018-01-01

We theoretically investigate the fluctuation of a pure spin current induced by the spin Seebeck effect and spin pumping in a normal-metal-(NM-)ferromagnet(FM) bilayer system. Starting with a simple ferromagnet-insulator-(FI-)NM interface model with both spin-conserving and non-spin-conserving processes, we derive general expressions of the spin current and the spin-current noise at the interface within second-order perturbation of the FI-NM coupling strength, and estimate them for a yttrium-iron-garnet-platinum interface. We show that the spin-current noise can be used to determine the effective spin carried by a magnon modified by the non-spin-conserving process at the interface. In addition, we show that it provides information on the effective spin of a magnon, heating at the interface under spin pumping, and spin Hall angle of the NM.

Resonant absorption induced fast melting studied with mid-IR QCLs.

PubMed

Lu, Jie; Lv, Yankun; Ji, Youxin; Tang, Xiaoliang; Qi, Zeming; Li, Liangbin

2017-02-01

We demonstrate the use of a pump-probe setup based on two mid-infrared quantum cascade lasers (QCLs) to investigate the melting and crystallization of materials through resonant absorption. A combination of pump and probe beams fulfills the two-color synchronous detection. Furthermore, narrow linewidth advances the accuracy of measurements and the character of broad tuning range of QCLs enables wide applications in various sample and multiple structures. 1-Eicosene was selected as a simple model system to verify the feasibility of this method. A pulsed QCL was tuned to the absorption peak of CH 2 bending vibration at 1467 cm -1 to resonantly heat the sample. The other QCL in continuous mode was tuned to 1643 cm -1 corresponding the C=C stretching vibration to follow the fast melting dynamics. By monitoring the transmission intensity variation of pump and probe beams during pump-probe experiments, the resonant absorption induced fast melting and re-crystallization of 1-Eicosene can be studied. Results show that the thermal effect and melting behaviors strongly depend on the pump wavelength (resonant or non-resonant) and energy, as well as the pump time. The realization and detection of melting and recrystallization can be performed in tens of milliseconds, which improves the time resolution of melting process study based on general mid-infrared spectrum by orders of magnitude. The availability of resonant heating and detections based on mid-infrared QCLs is expected to enable new applications in melting study.

Dynamics of defect-induced dark solitons in an exciton-polariton condensate

NASA Astrophysics Data System (ADS)

Opala, Andrzej; Pieczarka, Maciej; Bobrovska, Nataliya; Matuszewski, Michał

2018-04-01

We study theoretically the emission of dark solitons induced by a moving defect in a nonresonantly pumped exciton-polariton condensate. The number of created dark solitons per unit of time is found to be strongly dependent on the pump power. We relate the observed dynamics of this process to the oscillations of the drag force experienced by the condensate. We investigate the stability of the polariton quantum fluid and present various types of dynamics depending on the condensate and moving obstacle parameters. Furthermore, we provide analytical expressions for dark soliton dynamics using the variational method adapted to the nonequilibrium polariton system. The determined dynamical equations are found to be in excellent agreement with the results of numerical simulations.

Relative phase noise induced impairment in M-ary phase-shift-keying coherent optical communication system using distributed fiber Raman amplifier.

PubMed

Cheng, Jingchi; Tang, Ming; Fu, Songnian; Shum, Perry Ping; Liu, Deming

2013-04-01

We show for the first time, to the best of our knowledge, that, in a coherent communication system that employs a phase-shift-keying signal and Raman amplification, besides the pump relative intensity noise (RIN) transfer to the amplitude, the signal's phase will also be affected by pump RIN through the pump-signal cross-phase modulation. Although the average pump power induced linear phase change can be compensated for by the phase-correction algorithm, a relative phase noise (RPN) parameter has been found to characterize pump RIN induced stochastic phase noise. This extra phase noise brings non-negligible system impairments in terms of the Q-factor penalty. The calculation shows that copumping leads to much more stringent requirements to pump RIN, and relatively larger fiber dispersion helps to suppress the RPN induced impairment. A higher-order phase-shift keying (PSK) signal is less tolerant to noise than a lower-order PSK.

A Theoretical Model Analysis of Absorption of a Three level Diode Pumped Alkali Laser

DTIC Science & Technology

2009-03-01

2.10) 103 Bibliography Demtroder, Wolfgang . Laser Spectroscopy: Basic Concepts and Instrumentation. Berlin: Springer...Konefal Z., “Observation of collision induced processes in rubidium-ethane vapour,” Optics Communication, 164:95-105 (1999). Krause , L

Ultralow-power and ultrafast all-optical tunable plasmon-induced transparency in metamaterials at optical communication range.

PubMed

Zhu, Yu; Hu, Xiaoyong; Fu, Yulan; Yang, Hong; Gong, Qihuang

2013-01-01

Actively all-optical tunable plasmon-induced transparency in metamaterials paves the way for achieving ultrahigh-speed quantum information processing chips. Unfortunately, up to now, very small experimental progress has been made for all-optical tunable plasmon-induced transparency in metamaterials in the visible and near-infrared range because of small third-order optical nonlinearity of conventional materials. The achieved operating pump intensity was as high as several GW/cm(2) order. Here, we report an ultralow-power and ultrafast all-optical tunable plasmon-induced transparency in metamaterials coated on polycrystalline indium-tin oxide layer at the optical communication range. Compared with previous reports, the threshold pump intensity is reduced by four orders of magnitude, while an ultrafast response time of picoseconds order is maintained. This work not only offers a way to constructing photonic materials with large nonlinearity and ultrafast response, but also opens up the possibility for realizing quantum solid chips and ultrafast integrated photonic devices based on metamaterials.

Ultralow-power and ultrafast all-optical tunable plasmon-induced transparency in metamaterials at optical communication range

PubMed Central

Zhu, Yu; Hu, Xiaoyong; Fu, Yulan; Yang, Hong; Gong, Qihuang

2013-01-01

Actively all-optical tunable plasmon-induced transparency in metamaterials paves the way for achieving ultrahigh-speed quantum information processing chips. Unfortunately, up to now, very small experimental progress has been made for all-optical tunable plasmon-induced transparency in metamaterials in the visible and near-infrared range because of small third-order optical nonlinearity of conventional materials. The achieved operating pump intensity was as high as several GW/cm2 order. Here, we report an ultralow-power and ultrafast all-optical tunable plasmon-induced transparency in metamaterials coated on polycrystalline indium-tin oxide layer at the optical communication range. Compared with previous reports, the threshold pump intensity is reduced by four orders of magnitude, while an ultrafast response time of picoseconds order is maintained. This work not only offers a way to constructing photonic materials with large nonlinearity and ultrafast response, but also opens up the possibility for realizing quantum solid chips and ultrafast integrated photonic devices based on metamaterials. PMID:23903825

Effects of surface nanostructuring and impurity doping on ultrafast carrier dynamics of silicon photovoltaic cells: a pump-probe study

NASA Astrophysics Data System (ADS)

Chen, Tianyu; Nam, Yoon-Ho; Wang, Xinke; Han, Peng; Sun, Wenfeng; Feng, Shengfei; Ye, Jiasheng; Song, Jae-Won; Lee, Jung-Ho; Zhang, Chao; Zhang, Yan

2018-01-01

We present femtosecond optical pump-terahertz probe studies on the ultrafast dynamical processes of photo-generated charge carriers in silicon photovoltaic cells with various nanostructured surfaces and doping densities. The pump-probe measurements provide direct insight on the lifetime of photo-generated carriers, frequency-dependent complex dielectric response along with photoconductivity of silicon photovoltaic cells excited by optical pump pulses. A lifetime of photo-generated carriers of tens of nanosecond is identified from the time-dependent pump-induced attenuation of the terahertz transmission. In addition, we find a large value of the imaginary part of the dielectric function and of the real part of the photoconductivity in silicon photovoltaic cells with micron length nanowires. We attribute these findings to the result of defect-enhanced electron-photon interactions. Moreover, doping densities of phosphorous impurities in silicon photovoltaic cells are also quantified using the Drude-Smith model with our measured frequency-dependent complex photoconductivities.

Pump-Probe Fragmentation Action Spectroscopy: A Powerful Tool to Unravel Light-Induced Processes in Molecular Photocatalysts.

PubMed

Imanbaew, Dimitri; Lang, Johannes; Gelin, Maxim F; Kaufhold, Simon; Pfeffer, Michael G; Rau, Sven; Riehn, Christoph

2017-05-08

We present a proof of concept that ultrafast dynamics combined with photochemical stability information of molecular photocatalysts can be acquired by electrospray ionization mass spectrometry combined with time-resolved femtosecond laser spectroscopy in an ion trap. This pump-probe "fragmentation action spectroscopy" gives straightforward access to information that usually requires high purity compounds and great experimental efforts. Results of gas-phase studies on the electronic dynamics of two supramolecular photocatalysts compare well to previous findings in solution and give further evidence for a directed electron transfer, a key process for photocatalytic hydrogen generation. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Induced charge electroosmosis micropumps using arrays of Janus micropillars.

PubMed

Paustian, Joel S; Pascall, Andrew J; Wilson, Neil M; Squires, Todd M

2014-09-07

We report on a microfluidic AC-driven electrokinetic pump that uses Induced Charge Electro-Osmosis (ICEO) to generate on-chip pressures. ICEO flows occur when a bulk electric field polarizes a metal object to induce double layer formation, then drives electroosmotic flow. A microfabricated array of metal-dielectric Janus micropillars breaks the symmetry of ICEO flow, so that an AC electric field applied across the array drives ICEO flow along the length of the pump. When pumping against an external load, a pressure gradient forms along the pump length. The design was analyzed theoretically with the reciprocal theorem. The analysis reveals a maximum pressure and flow rate that depend on the ICEO slip velocity and micropillar geometry. We then fabricate and test the pump, validating our design concept by demonstrating non-local pressure driven flow using local ICEO slip flows. We varied the voltage, frequency, and electrolyte composition, measuring pump pressures of 15-150 Pa. We use the pump to drive flows through a high-resistance microfluidic channel. We conclude by discussing optimization routes suggested by our theoretical analysis to enhance the pump pressure.

Hypothesized diprotomeric enzyme complex supported by stochastic modelling of palytoxin-induced Na/K pump channels

PubMed Central

Vilallonga, Gabriel D.; de Almeida, Antônio-Carlos G.; Ribeiro, Kelison T.; Campos, Sergio V. A.

2018-01-01

The sodium–potassium pump (Na+/K+ pump) is crucial for cell physiology. Despite great advances in the understanding of this ionic pumping system, its mechanism is not completely understood. We propose the use of a statistical model checker to investigate palytoxin (PTX)-induced Na+/K+ pump channels. We modelled a system of reactions representing transitions between the conformational substates of the channel with parameters, concentrations of the substates and reaction rates extracted from simulations reported in the literature, based on electrophysiological recordings in a whole-cell configuration. The model was implemented using the UPPAAL-SMC platform. Comparing simulations and probabilistic queries from stochastic system semantics with experimental data, it was possible to propose additional reactions to reproduce the single-channel dynamic. The probabilistic analyses and simulations suggest that the PTX-induced Na+/K+ pump channel functions as a diprotomeric complex in which protein–protein interactions increase the affinity of the Na+/K+ pump for PTX. PMID:29657808

Liquid Hydrogen Pump

DTIC Science & Technology

1964-11-01

Diagram 183 65 Hub’ess Inducer Impeller and Shroud Prior Prior to Brazing 189 66 Hubless Inducer Impeller Assembly After Brazing and Finish Machining...Cross-Section of Shrouded Hubless Indjcer Pump 195 71 Liquid Hydrogen Pump Test Site, San Tan, Arizona 197 72 Installation of Pump and Overall )est Site...speed of 300,000. It operates at a tip speed of 1260 ft per second. The impeller is a shrouded wheel designed with sufficient strength to carry the

Phase-sensitive optical coherence tomography characterization of pulse-induced trabecular meshwork displacement in ex vivo non-human primate eyes

NASA Astrophysics Data System (ADS)

Li, Peng; Reif, Roberto; Zhi, Zhongwei; An, Lin; Martin, Elizabeth; Shen, Tueng T.; Johnstone, Murray; Wang, Ruikang K.

2013-03-01

Purpose. It is suspected that the abnormalities of aqueous outflow pump composed of trabecular meshwork (TM) and Schlemm's canal (SC) results in the increased outflow resistance and then elevated intraocular pressure (IOP) in initial glaucoma. In order to explore the casual mechanism and the early diagnosis of glaucoma, the dynamic characterizations of aqueous outflow pump were explored. Methods. As a functional extension of optical coherence tomography (OCT), tissue Doppler OCT (tissue-DOCT) method capable of measuring the slow tissue movement was developed. The tissue-DOCT imaging was conducted on the corneo-scleral limbus of 4 monkey eyes. The eye was mounted in an anterior segment holder, together with a perfusion system to control the mean IOP and to induce the cyclic IOP transients with amplitude 3 mm Hg at frequency 1 pulse/second. IOP was monitored on-line by a pressure transducer. Tissue-DOCT data and pressure data were recorded simultaneously. The IOP-transient induced Doppler velocity, displacement and strain rate of TM and the normalized area of SC were quantified at 7 different mean IOPs (5, 8, 10, 20, 30, 40, 50 mm Hg). Results. The outflow system, including TM, SC and CCs, was visualized in the micro-structural imaging. The IOP-transient induced pulsatile TM movement and SC deformation were detected and quantified by tissue-DOCT. The TM movement was depth-dependent and the largest movement was located in the area closest to SC endothelium (SCE). Both the pulsations of TM and SC were found to be synchronous with the IOP pulse wave. At 8 mm Hg IOP, the global TM movement was around 0.65μm during one IOP transient. As IOP elevated, a gradual attenuation of TM movement and SC deformation was observed. Conclusions. The observed pulsation of TM and SC induced by the pulsatile IOP transients was in good agreement with the predicated role of TM and SC acting as a biomechanical pump (pumping aqueous from anterior chamber into SC and from SC into CCs) in the aqueous outflow system. As the IOP elevated, the attenuated pulsation amplitude of the aqueous outflow pump indicated the failure of the mechanical pump and the increase of aqueous outflow resistance. The promising results revealed the potential of using the proposed tissue-DOCT for diagnosis and associated therapeutic guidance of the initial and progressive glaucoma process by monitoring the pulsation of the outflow pump.

A model of annular linear induction pumps

DOE Office of Scientific and Technical Information (OSTI.GOV)

Momozaki, Yoichi

2016-10-27

The present work explains how the magnetic field and the induced current are obtained when the distributed coils are powered by a 3 phase power supply.  From the magnetic field and the induced current, the thrust and the induction losses in the pump can be calculated to estimate the pump performance.

Time-resolved investigations of the non-thermal ablation process of graphite induced by femtosecond laser pulses

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kalupka, C., E-mail: christian.kalupka@llt.rwth-aachen.de; Finger, J.; Reininghaus, M.

2016-04-21

We report on the in-situ analysis of the ablation dynamics of the, so-called, laser induced non-thermal ablation process of graphite. A highly oriented pyrolytic graphite is excited by femtosecond laser pulses with fluences below the classic thermal ablation threshold. The ablation dynamics are investigated by axial pump-probe reflection measurements, transversal pump-probe shadowgraphy, and time-resolved transversal emission photography. The combination of the applied analysis methods allows for a continuous and detailed time-resolved observation of the non-thermal ablation dynamics from several picoseconds up to 180 ns. Formation of large, μm-sized particles takes place within the first 3.5 ns after irradiation. The following propagation ofmore » ablation products and the shock wave front are tracked by transversal shadowgraphy up to 16 ns. The comparison of ablation dynamics of different fluences by emission photography reveals thermal ablation products even for non-thermal fluences.« less

Dynamics of cavitating cascades and inducer pumps

NASA Technical Reports Server (NTRS)

Brennen, C. E.; Acosta, A. J.

1981-01-01

Report chronicles advances in understanding and predicting unsteady dynamic characteristics of cavitating cascades and inducer pumps. It includes bibliography of 19 papers authored between 1972 and 1980.

Characterization of an induced pressure pumping force for microfluidics

NASA Astrophysics Data System (ADS)

Jiang, Hai; Fan, Na; Peng, Bei; Weng, Xuan

2017-05-01

The electro-osmotic pumping and pressure-driven manipulation of fluids are considered as the most common strategies in microfluidic devices. However, both of them exhibit major disadvantages such as hard integration and high reagent consumption, and they are destructive methods for detection and photo bleaching. In this paper, an electric field-effect flow control approach, combining the electro-osmotic pumping force and the pressure-driven pumping force, was developed to generate the induced pressure-driven flow in a T-shaped microfluidic chip. Electro-osmotic flow between the T-intersection and two reservoirs was demonstrated, and it provided a stable, continuous, and electric field-free flow in the section of the microchannel without the electrodes. The velocity of the induced pressure-driven flow was linearly proportional to the applied voltages. Both numerical and experimental investigations were conducted to prove the concept, and the experimental results showed good agreement with the numerical simulations. In comparison to other induced pressure pumping methods, this approach can induce a high and controllable pressure drop in the electric field-free segment, subsequently causing an induced pressure-driven flow for transporting particles or biological cells. In addition, the generation of bubbles and the blocking of the microchannel are avoided.

A reactive transport model for the quantification of risks induced by groundwater heat pump systems in urban aquifers

NASA Astrophysics Data System (ADS)

García-Gil, Alejandro; Epting, Jannis; Ayora, Carlos; Garrido, Eduardo; Vázquez-Suñé, Enric; Huggenberger, Peter; Gimenez, Ana Cristina

2016-11-01

Shallow geothermal resource exploitation through the use of groundwater heat pump systems not only has hydraulic and thermal effects on the environment but also induces physicochemical changes that can compromise the operability of installations. This study focuses on chemical clogging and dissolution subsidence processes observed during the geothermal re-injection of pumped groundwater into an urban aquifer. To explain these phenomena, two transient reactive transport models of a groundwater heat pump installation in an alluvial aquifer were used to reproduce groundwater-solid matrix interactions occurring in a surrounding aquifer environment during system operation. The models couple groundwater flow, heat and solute transport together with chemical reactions. In these models, the permeability distribution in space changes with precipitation-dissolution reactions over time. The simulations allowed us to estimate the calcite precipitation rates and porosity variations over space and time as a function of existent hydraulic gradients in an aquifer as well as the intensity of CO2 exchanges with the atmosphere. The results obtained from the numerical model show how CO2 exolution processes that occur during groundwater reinjection into an aquifer and calcite precipitation are related to hydraulic efficiency losses in exploitation systems. Finally, the performance of reinjection wells was evaluated over time according to different scenarios until the systems were fully obstructed. Our simulations also show a reduction in hydraulic conductivity that forces re-injected water to flow downwards, thereby enhancing the dissolution of evaporitic bedrock and producing subsidence that can ultimately result in a dramatic collapse of the injection well infrastructure.

Predicting performance of axial pump inducer of LOX booster turbo-pump of staged combustion cycle based rocket engine using CFD

NASA Astrophysics Data System (ADS)

Mishra, Arpit; Ghosh, Parthasarathi

2015-12-01

For low cost, high thrust, space missions with high specific impulse and high reliability, inert weight needs to be minimized and thereby increasing the delivered payload. Turbopump feed system for a liquid propellant rocket engine (LPRE) has the highest power to weight ratio. Turbopumps are primarily equipped with an axial flow inducer to achieve the high angular velocity and low suction pressure in combination with increased system reliability. Performance of the turbopump strongly depends on the performance of the inducer. Thus, for designing a LPRE turbopump, demands optimization of the inducer geometry based on the performance of different off-design operating regimes. In this paper, steady-state CFD analysis of the inducer of a liquid oxygen (LOX) axial pump used as a booster pump for an oxygen rich staged combustion cycle rocket engine has been presented using ANSYS® CFX. Attempts have been made to obtain the performance characteristic curves for the LOX pump inducer. The formalism has been used to predict the performance of the inducer for the throttling range varying from 80% to 113% of nominal thrust and for the different rotational velocities from 4500 to 7500 rpm. The results have been analysed to determine the region of cavitation inception for different inlet pressure.

Numerical study on the responses of groundwater and strata to pumping and recharge in a deep confined aquifer

NASA Astrophysics Data System (ADS)

Zhang, Yang-Qing; Wang, Jian-Hua; Chen, Jin-Jian; Li, Ming-Guang

2017-05-01

Groundwater drawdown and strata settlements induced by dewatering in confined aquifers can be relieved by artificial recharge. In this study, numerical simulations of a field multi-well pumping-recharge test in a deep confined aquifer are conducted to analyze the responses of groundwater and strata to pumping and recharge. A three-dimensional numerical model is developed in a finite-difference software, which considers the fluid-mechanical interaction using the Biot consolidation theory. The predicted groundwater drawdown and ground settlements are compared to the measured data to confirm the validation of the numerical analysis of the pumping and recharge. Both numerical results and measured data indicate that the effect of recharge on controlling the groundwater drawdown and strata settlements correlates with the injection rate and well arrangements. Since the groundwater drawdown induced by pumping can be controlled by artificial recharge, soil compression can be relieved by reducing the changes of effective stress of the soils. Consequently, strata settlement induced by pumping can be relieved by artificial recharge and ground settlements can be eliminated if an appropriate injection rate and well arrangement are being determined. Moreover, the changes of the pore pressure and seepage force induced by pumping and recharge will also result in significant horizontal deformations in the strata near the recharge wells.

Interband coherence induced correction to Thouless pumping: possible observation in cold-atom systems

NASA Astrophysics Data System (ADS)

Raghava, Gudapati Naresh; Zhou, Longwen; Gong, Jiangbin

2017-08-01

In Thouless pump, the charge transport in a one-dimensional insulator over an adiabatic cycle is topologically quantized. For nonequilibrium initial states, however, interband coherence will induce a previously unknown contribution to Thouless pumping. Though not geometric in nature, this contribution is independent of the time scale of the pumping protocol. In this work, we perform a detailed analysis of our previous finding [H.L. Wang et al., Phys. Rev. B 91, 085420 (2015)] in an already available cold-atom setup. We show that initial states with interband coherence can be obtained via a quench of the system's Hamiltonian. Adiabatic pumping in the post-quench system are then examined both theoretically and numerically, in which the interband coherence is shown to play an important role and can hence be observed experimentally. By choosing adiabatic protocols with different switching-on rates, we also show that the contribution of interband coherence to adiabatic pumping can be tuned. It is further proposed that the interband coherence induced correction to Thouless pumping may be useful in capturing a topological phase transition point. All our results have direct experimental interests.

Sustained multi-kHz flamefront and 3-component velocity-field measurements for the study of turbulent flames

NASA Astrophysics Data System (ADS)

Boxx, I.; Stöhr, M.; Carter, C.; Meier, W.

2009-04-01

We describe an approach of imaging the dynamic interaction of the flamefront and flowfield. Here, a diode-pumped Nd:YLF laser operating at 5 kHz is used to pump a dye laser, which is then frequency doubled to 283 nm to probe flamefront OH, while a dual cavity diode-pumped Nd:YAG system produces pulse-pairs for particle image velocimetry (PIV). CMOS digital cameras are used to detect both planar laser-induced fluorescence (PLIF) and particle scattering (in a stereo arrangement) such that a 5 kHz measurement frequency is attained. This diagnostic is demonstrated in lifted-jet and swirl-stabilized flames, wherein the dynamics of the flame stabilization processes are seen. Nonperiodic effects such as local ignition and/or extinction, lift-off and flashback events, and their histories can be captured by this technique. As such, this system has the potential to significantly extend our understanding of nonstationary combustion processes relevant to industrial and technical applications.

Continuous-wave infrared optical gain and amplified spontaneous emission at ultralow threshold by colloidal HgTe quantum dots.

PubMed

Geiregat, Pieter; Houtepen, Arjan J; Sagar, Laxmi Kishore; Infante, Ivan; Zapata, Felipe; Grigel, Valeriia; Allan, Guy; Delerue, Christophe; Van Thourhout, Dries; Hens, Zeger

2018-01-01

Colloidal quantum dots (QDs) raise more and more interest as solution-processable and tunable optical gain materials. However, especially for infrared active QDs, optical gain remains inefficient. Since stimulated emission involves multifold degenerate band-edge states, population inversion can be attained only at high pump power and must compete with efficient multi-exciton recombination. Here, we show that mercury telluride (HgTe) QDs exhibit size-tunable stimulated emission throughout the near-infrared telecom window at thresholds unmatched by any QD studied before. We attribute this unique behaviour to surface-localized states in the bandgap that turn HgTe QDs into 4-level systems. The resulting long-lived population inversion induces amplified spontaneous emission under continuous-wave optical pumping at power levels compatible with solar irradiation and direct current electrical pumping. These results introduce an alternative approach for low-threshold QD-based gain media based on intentional trap states that paves the way for solution-processed infrared QD lasers and amplifiers.

Continuous-wave infrared optical gain and amplified spontaneous emission at ultralow threshold by colloidal HgTe quantum dots

NASA Astrophysics Data System (ADS)

Geiregat, Pieter; Houtepen, Arjan J.; Sagar, Laxmi Kishore; Infante, Ivan; Zapata, Felipe; Grigel, Valeriia; Allan, Guy; Delerue, Christophe; van Thourhout, Dries; Hens, Zeger

2018-01-01

Colloidal quantum dots (QDs) raise more and more interest as solution-processable and tunable optical gain materials. However, especially for infrared active QDs, optical gain remains inefficient. Since stimulated emission involves multifold degenerate band-edge states, population inversion can be attained only at high pump power and must compete with efficient multi-exciton recombination. Here, we show that mercury telluride (HgTe) QDs exhibit size-tunable stimulated emission throughout the near-infrared telecom window at thresholds unmatched by any QD studied before. We attribute this unique behaviour to surface-localized states in the bandgap that turn HgTe QDs into 4-level systems. The resulting long-lived population inversion induces amplified spontaneous emission under continuous-wave optical pumping at power levels compatible with solar irradiation and direct current electrical pumping. These results introduce an alternative approach for low-threshold QD-based gain media based on intentional trap states that paves the way for solution-processed infrared QD lasers and amplifiers.

Performance of MgO:PPLN, KTA, and KNbO₃ for mid-wave infrared broadband parametric amplification at high average power.

PubMed

Baudisch, M; Hemmer, M; Pires, H; Biegert, J

2014-10-15

The performance of potassium niobate (KNbO₃), MgO-doped periodically poled lithium niobate (MgO:PPLN), and potassium titanyl arsenate (KTA) were experimentally compared for broadband mid-wave infrared parametric amplification at a high repetition rate. The seed pulses, with an energy of 6.5 μJ, were amplified using 410 μJ pump energy at 1064 nm to a maximum pulse energy of 28.9 μJ at 3 μm wavelength and at a 160 kHz repetition rate in MgO:PPLN while supporting a transform limited duration of 73 fs. The high average powers of the interacting beams used in this study revealed average power-induced processes that limit the scaling of optical parametric amplification in MgO:PPLN; the pump peak intensity was limited to 3.8  GW/cm² due to nonpermanent beam reshaping, whereas in KNbO₃ an absorption-induced temperature gradient in the crystal led to permanent internal distortions in the crystal structure when operated above a pump peak intensity of 14.4  GW/cm².

Strong-field dissociation of CS2+ via a pump/dump-like mechanism

NASA Astrophysics Data System (ADS)

Severt, T.; Zohrabi, M.; Betsch, K. J.; Ablikim, U.; Jochim, Bethany; Carnes, K. D.; Zeng, S.; Esry, B. D.; Ben-Itzhak, I.; Uhlíková, T.

2014-05-01

Laser-induced dissociation of the quasi-bound electronic ground state of CS2+ is investigated in intense laser pulses (<55 fs, <1016 W/cm2). Photodissociation is observed to be the dominant dissociation pathway; however, a more curious feature in the kinetic energy release spectrum suggests no significant energy gain from the initial states. We propose a pump/dump-like mechanism to explain this observed feature. Contrary to the conventional pump/dump control scheme, this process occurs within a single laser pulse, where the time delay is caused by the molecular structure. The process begins when the vibrational wavepacket in the electronic ground state of CS2+ is pumped into the electronic first excited state's continuum by a single photon. After a period of stretching at an energy above the potential barrier, the emission of a second photon is stimulated by the same laser pulse, most likely at the Condon point. Supported by the Chemical Sciences, Geosciences, and Biosciences Division, Office of Basic Energy Sciences, Office of Science, U.S. Department of Energy, Grants DE-FG02-86ER13491 and DE-FG02-09ER16115. TU supported by GACR and MetaCentrum.

Laser-Induced Fluorescence Measurements of Translational Temperature and Relative Cycle Number by use of Optically Pumped Trace-Sodium Vapor

NASA Technical Reports Server (NTRS)

Dobson, Chris C.

1998-01-01

Sodium fluorescence induced by a narrow bandwidth tunable laser has been used to measure temperature, pressure, axial velocity and species concentrations in wind tunnels, rocket engine exhausts and the upper atmosphere. Optical pumping of the ground states of the sodium, however, can radically alter the shape of the laser induced fluorescence excitation spectrum, complicating such measurements. Here a straightforward extension of rate equations originally proposed to account for the features of the pumped spectrum is to make temperature measurements from spectra taken in pumped vapor. Also determined from the spectrum is the relative fluorescence cycle number, which has application to measurement of diffusion rate and transverse flow velocity. The accuracy of both the temperature and cycle-number measurements is comparable with that of temperature measurements made in the absence of pumping.

Three-beam double stimulated Raman scatterings: Cascading configuration

NASA Astrophysics Data System (ADS)

Rao, B. Jayachander; Cho, Minhaeng

2018-03-01

Two-beam stimulated Raman scattering (SRS) has been used in diverse label-free spectroscopy and imaging applications of live cells, biological tissues, and functional materials. Recently, we developed a theoretical framework for the three-beam double SRS processes that involve pump, Stokes, and depletion beams, where the pump-Stokes and pump-depletion SRS processes compete with each other. It was shown that the net Stokes gain signal can be suppressed by increasing the depletion beam intensity. The theoretical prediction has been experimentally confirmed recently. In the previous scheme for a selective suppression of one SRS by making it compete with another SRS, the two SRS processes occur in a parallel manner. However, there is another possibility of three-beam double SRS scheme that can be of use to suppress either Raman gain of the Stokes beam or Raman loss of the pump beam by depleting the Stokes photons with yet another SRS process induced by the pair of Stokes and another (second) Stokes beam. This three-beam double SRS process resembles a cascading energy transfer process from the pump beam to the first Stokes beam (SRS-1) and subsequently from the first Stokes beam to the second Stokes beam (SRS-2). Here, the two stimulated Raman gain-loss processes are associated with two different Raman-active vibrational modes of solute molecule. In the present theory, both the radiation and the molecules are treated quantum mechanically. We then show that the cascading-type three-beam double SRS can be described by coupled differential equations for the photon numbers of the pump and Stokes beams. From the approximate solutions as well as exact numerical calculation results for the coupled differential equations, a possibility of efficiently suppressing the stimulated Raman loss of the pump beam by increasing the second Stokes beam intensity is shown and discussed. To further prove a potential use of this scheme for developing a super-resolution SRS microscopy, we present a theoretical expression and numerical simulation results for the full-width-at-half-maximum of SRS imaging point spread function, assuming that the pump and Stokes beam profiles are Gaussian and the second Stokes beam has a doughnut-shaped spatial profile. It is clear that the spatial resolution with the present 3-beam cascading SRS method can be enhanced well beyond the diffraction limit. We anticipate that the present work will provide a theoretical framework for a super-resolution stimulated Raman scattering microscopy that is currently under investigation.

DISK PUMP FEASIBILITY INVESTIGATION,

DTIC Science & Technology

system as an inducer and/or mainstage pump for liquid rocket applications. This investigation consisted of the analysis, design, and test of a disk...pumping action is a function of the viscous properties of the pumped fluid. (2) The pump does not require the conventional pump lifting forces. ( 3 ...with no apparent head deterioration. The representative maximum suction specific speed at a 3 % head drop was never reached. The pump demonstrated

Experimental testing of centrifugal pump: small and medium sized enterprise product

NASA Astrophysics Data System (ADS)

Ismail, R.; Paddiyatu, F.; Khafidh, M.; Nugroho, S.; Sugiyanto, S.; Jamari, J.

2014-06-01

This paper reports the experimental testing for centrifugal pump for fisherman ship, manufactured by small and medium sized enterprises in Central Java Province, Indonesia. The research covers material analysis, component observation, endurance and vibration test. Six centrifugal pumps are tested and three main pump components are discussed: shaft, bearings and seals. The results show that the material of the shaft is predicted to support and transmit the load from the engine to impeller. The problem found in the tolerance and geometry accuracy of the shaft which causes difficulties during assembling process, excessive wear and leakage during testing. From the endurance and vibration test, the ball bearings fail and lock the shaft due to the fatigue on the rolling elements and raceways. The oil seal and water seal also fail in maintaining the oil and water in the chamber and induce the unlubricated system for the ball bearings. Some suggestions are delivered to improve the product quality of the centrifugal pump. A good quality of the centrifugal pump for fishermen ship and long life span is expected to be produced by local SMEs to win the free trade competition in the Indonesian market.

Rotary blood pump

NASA Astrophysics Data System (ADS)

Bozeman, Richard J.; Akkerman, James W.; Aber, Greg S.; Vandamm, George A.; Bacak, James W.; Svejkovsky, Paul A.; Benkowski, Robert J.

1993-11-01

A rotary blood pump is presented. The pump includes a pump housing for receiving a flow straightener, a rotor mounted on rotor bearings and having an inducer portion and an impeller portion, and a diffuser. The entrance angle, outlet angle, axial, and radial clearances of the blades associated with the flow straightener, inducer portion, impeller portion, and diffuser are optimized to minimize hemolysis while maintaining pump efficiency. The rotor bearing includes a bearing chamber that is filled with crosslinked blood or other bio-compatible material. A back emf integrated circuit regulates rotor operation and a microcomputer may be used to control one or more back emf integrated circuits. A plurality of magnets are disposed in each of a plurality of impeller blades with a small air gap. A stator may be axially adjusted on the pump housing to absorb bearing load and maximize pump efficiency.

DIRECT CURRENT ELECTROMAGNETIC PUMP

DOEpatents

Barnes, A.H.

1957-11-01

An improved d-c electromagnetic pump is presented in which the poles, and consequently the magetic gap at the poles, are tapered to be wider at the upstream end. In addition, the cross section of the tube carryiQ the liquid metal is tapered so that the velocity of the pumped liquid increases in the downstream direction at a rate such that the counter-induced voltage in the liquid metal remains constant as it traverses the region between the poles. This configuration compensates for the distortion of the magnetic field caused by the induced voltage that would otherwise result in the lowering of the pumping capacity. This improved electromagnetic pump as practical application in the pumping of liquid metal coolants for nuclear reactors where conventional positive displacement pumps have proved unsatisfactory due to the high temperatures and the corrosive properties of the liquid metals involved.

Rotary blood pump

NASA Technical Reports Server (NTRS)

Bozeman, Richard J. (Inventor); Akkerman, James W. (Inventor); Aber, Greg S. (Inventor); Vandamm, George A. (Inventor); Bacak, James W. (Inventor); Svejkovsky, Paul A. (Inventor); Benkowski, Robert J. (Inventor)

1993-01-01

A rotary blood pump is presented. The pump includes a pump housing for receiving a flow straightener, a rotor mounted on rotor bearings and having an inducer portion and an impeller portion, and a diffuser. The entrance angle, outlet angle, axial, and radial clearances of the blades associated with the flow straightener, inducer portion, impeller portion, and diffuser are optimized to minimize hemolysis while maintaining pump efficiency. The rotor bearing includes a bearing chamber that is filled with crosslinked blood or other bio-compatible material. A back emf integrated circuit regulates rotor operation and a microcomputer may be used to control one or more back emf integrated circuits. A plurality of magnets are disposed in each of a plurality of impeller blades with a small air gap. A stator may be axially adjusted on the pump housing to absorb bearing load and maximize pump efficiency.

Twin-spool turbopumps for ''low'' net positive suction pressure operations

NASA Technical Reports Server (NTRS)

Bair, E. K.; Campbell, W. E.; Ford, O. I.

1970-01-01

Modified single-shaft turbopump incorporates inducer and main pump, each separately driven at different speeds through coaxial-shaft arrangement. Inducer operates at low speed for low net positive suction pressure, main pump operates at high speed to generate high pressure. This arrangement requires no external control for the inducer.

Laser Induced Optical Pumping Measurements of Cross Sections for Fine and Hyperfine Structure Transitions in Sodium Induced by Collisions with Helium Argon Atoms

NASA Technical Reports Server (NTRS)

Dobson, Chris C.; Sung, C. C.

1998-01-01

Optical pumping of the ground states of sodium can radically alter the shape of the laser induced fluorescence excitation spectrum, complicating measurements of temperature, pressure, etc., which are based on these spectra. Modeling of the fluorescence using rate equations for the eight hyperfine states of the sodium D manifolds can be used to quantify the contribution to the ground state pumping of transitions among the hyperfine excited states induced by collisions with buffer gas atoms. This model is used here to determine, from the shape of experimental spectra, cross sections for (Delta)F transitions of the P(sub 3/2) state induced by collisions with helium and argon atoms, for a range of values assumed for the P(sub 1/2), (Delta)F cross sections. The hyperfine cross sections measured using this method, which is thought to be novel, are compared with cross sections for transitions involving polarized magnetic substates, m(sub F), measured previously using polarization sensitive absorption. Also, fine structure transition ((Delta)J) cross sections were measured in the pumped vapor, giving agreement with previous measurements made in the absence of pumping.

Laser-Induced Optical Pumping Measurements of Cross Section for Fine- and Hyperfine-Structure Transitions in Sodium Induced by Collisions with Helium and Argon Atoms

NASA Technical Reports Server (NTRS)

Dobson, Chris C.; Sung, C. C.

1999-01-01

Optical pumping of the ground states of sodium can radically alter the shape of the laser-induced fluorescence excitation spectrum, complicating measurements of temperature, pressure, etc., which are based on these spectra. Modeling of the fluorescence using rate equations for the eight hyperfine states of the sodium D manifolds can be used to quantify the contribution to the ground state pumping of transitions among the hyperfine excited states induced by collisions with buffer gas atoms. This model is used here to determine, from the shape of experimental spectra, cross sections lor DELTA.F transitions of the P(sub 3/2) state induced by collisions with helium and argon atoms, for a range of values assumed for the P(sub 1/2), DELTA.F cross sections. The hyperfine cross sections measured using this method, which to our knowledge is novel, are compared with cross sections for transitions involving polarized magnetic substates m(sub F) measured previously using polarization sensitive absorption. Also, fine-structure transition cross sections were measured in the pumped vapor, giving agreement with previous measurements made in the absence of pumping.

Laser-Induced Fluorescence Measurements of Translational Temperature and Relative Cycle Number by use of Optically Pumped Trace-Sodium Vapor

NASA Technical Reports Server (NTRS)

Dobson, Chris C.

1999-01-01

Sodium fluorescence induced by a narrow-bandwidth tunable laser has been used to measure temperature, pressure, axial velocity, and species concentrations in wind tunnels, rocket engine exhausts, and the upper atmosphere. Optical pumping of the ground states of the sodium, however, can radically alter the shape of the laser-induced fluorescence excitation spectrum, complicating such measurements. Here a straightforward extension of rate equations originally proposed to account for the features of the pumped spectrum is used to make temperature measurements from spectra taken in pumped vapor. Also determined from the spectrum is the relative fluorescence cycle number, which has application to measurement of diffusion rate and transverse flow velocity, The accuracy of both the temperature and the cycle-number measurements is comparable with that of temperature measurements made in the absence of pumping.

Acoustic parametric pumping of spin waves

NASA Astrophysics Data System (ADS)

Keshtgar, Hedyeh; Zareyan, Malek; Bauer, Gerrit E. W.

2014-11-01

Recent experiments demonstrated generation of spin currents by ultrasound. We can understand this acoustically induced spin pumping in terms of the coupling between magnetization and lattice waves. Here we study the parametric excitation of magnetization by longitudinal acoustic waves and calculate the acoustic threshold power. The induced magnetization dynamics can be detected by the spin pumping into an adjacent normal metal that displays the inverse spin Hall effect.

Thermodynamic performance of multi-stage gradational lead screw vacuum pump

NASA Astrophysics Data System (ADS)

Zhao, Fan; Zhang, Shiwei; Sun, Kun; Zhang, Zhijun

2018-02-01

As a kind of dry mechanical vacuum pump, the twin-screw vacuum pump has an outstanding pumping performance during operation, widely used in the semiconductor industry. Compared with the constant lead screw (CLS) vacuum pump, the gradational lead screw (GLS) vacuum pump is more popularly applied in recent years. Nevertheless, not many comparative studies on the thermodynamic performance of GLS vacuum pump can be found in the literature. Our study focuses on one type of GLS vacuum pump, the multi-stage gradational lead screw (MGLS) vacuum pump, gives a detailed description of its construction and illustrates it with the drawing. Based on the structural analysis, the thermodynamic procedure is divided into four distinctive processes, including sucking process, transferring (compressing) process, backlashing process and exhausting process. The internal mechanism of each process is qualitatively illustrated and the mathematical expressions of seven thermodynamic parameters are given under the ideal situation. The performance curves of MGLS vacuum pump are plotted by MATLAB software and compared with those of the CLS vacuum pump in the same case. The results can well explain why the MGLS vacuum pump has more favorable pumping performance than the CLS vacuum pump in saving energy, reducing noise and heat dissipation.

Heater-induced altitude descent of the EISCAT UHF ion line enhancements: Observations and modelling

NASA Astrophysics Data System (ADS)

Ashrafi, M.; Kosch, M. J.; Honary, F.

2006-01-01

On 12 November 2001, artificial optical annuli were produced using the EISCAT high-frequency (HF) ionospheric heating facility. This unusual phenomenon was induced using O-mode transmissions at 5.423 MHz with 550 MW effective isotropic radiated power and the pump beam dipped 9° south of the zenith. The pump frequency corresponds to the fourth electron gyroharmonic frequency at 215 km altitude. The EISCAT UHF radar observed a persistent pump-induced enhancement in the ion line backscatter power near the HF reflection altitude. The optical and radar signatures of HF pumping started at ˜230 km and descended to ˜220 km within ˜60 s. This effect has been modelled using the solution to differential equations describing pump-induced electron temperature and density perturbations. The decrease in altitude of the ion line by ˜10 km and changes in electron density have been modelled. The results show that a maximum electron temperature enhancement of up to ˜5700 K can be achieved on average, which is not sufficient to explain the observed optical emissions.

Axial Pump

NASA Technical Reports Server (NTRS)

Bozeman, Richard J., Jr. (Inventor); Akkerman, James W. (Inventor); Aber, Gregory S. (Inventor); VanDamm, George Arthur (Inventor); Bacak, James W. (Inventor); Svejkovsky, Paul A. (Inventor); Benkowski, Robert J. (Inventor)

1997-01-01

A rotary blood pump includes a pump housing for receiving a flow straightener, a rotor mounted on rotor bearings and having an inducer portion and an impeller portion, and a diffuser. The entrance angle, outlet angle, axial and radial clearances of blades associated with the flow straightener, inducer portion, impeller portion and diffuser are optimized to minimize hemolysis while maintaining pump efficiency. The rotor bearing includes a bearing chamber that is filled with cross-linked blood or other bio-compatible material. A back emf integrated circuit regulates rotor operation and a microcomputer may be used to control one or more back emf integrated circuits. A plurality of magnets are disposed in each of a plurality of impeller blades with a small air gap. A stator may be axially adjusted on the pump housing to absorb bearing load and maximize pump efficiency.

Intermediate-Size Inducer Pump design report. [LMFBR

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boardman, T.J.

1979-06-15

This report summarizes the mechanical, structural, and hydrodynamic design of the Intermediate-Size Inducer Pump (ISIP). The design was performed under Atomics International's DOE Base Technology Program by the Atomics International and Rocketdyne Divisions of Rockwell International. The pump was designed to utilize the FFTF prototype pump frame as a test vehicle to test the inducer, impeller, and diffuser plus necessary adapter hardware under simulated Large Scale Liquid Metal Fast Breeder Reactor service conditions. The report describes the design requirements including the purpose and objectives, and discusses those design efforts and considerations made to meet the requirements. Included in the reportmore » are appendices showing calculative methods and results. Also included are overall assembly and layout drawings plus some details used as illustrations for discussion of the design results and the results of water tests performed on a model of the inducer.« less

8-Dehydrosterols induce membrane traffic and autophagy defects through V-ATPase dysfunction in Saccharomyces cerevisae.

PubMed

Hernández, Agustín; Serrano-Bueno, Gloria; Perez-Castiñeira, José Román; Serrano, Aurelio

2015-11-01

8-Dehydrosterols are present in a wide range of biologically relevant situations, from human rare diseases to amine fungicide-treated fungi and crops. However, the molecular bases of their toxicity are still obscure. We show here that 8-dehydrosterols, but not other sterols, affect yeast vacuole acidification through V-ATPases. Moreover, erg2Δ cells display reductions in proton pumping rates consistent with ion-transport uncoupling in vitro. Concomitantly, subunit Vph1p shows conformational changes in the presence of 8-dehydrosterols. Expression of a plant vacuolar H(+)-pumping pyrophosphatase as an alternative H(+)-pump relieves Vma(-)-like phenotypes in erg2Δ-derived mutant cells. As a consequence of these acidification defects, endo- and exo-cytic traffic deficiencies that can be alleviated with a H(+)-pumping pyrophosphatase are also observed. Despite their effect on membrane traffic, 8-dehydrosterols do not induce endoplasmic reticulum stress or assembly defects on the V-ATPase. Autophagy is a V-ATPase dependent process and erg2Δ mutants accumulate autophagic bodies under nitrogen starvation similar to Vma(-) mutants. In contrast to classical Atg(-) mutants, this defect is not accompanied by impairment of traffic through the CVT pathway, processing of Pho8Δ60p, GFP-Atg8p localisation or difficulties to survive under nitrogen starvation conditions, but it is concomitant to reduced vacuolar protease activity. All in all, erg2Δ cells are autophagy mutants albeit some of their phenotypic features differ from classical Atg(-) defective cells. These results may pave the way to understand the aetiology of sterol-related diseases, the cytotoxic effect of amine fungicides, and may explain the tolerance to these compounds observed in plants. Copyright © 2015 Elsevier B.V. All rights reserved.

Electric Potential Across Epidermis and Its Role During Wound Healing Can Be Studied by Using an In Vitro Reconstructed Human Skin

PubMed Central

Moulin, Véronique J.; Dubé, Jean; Rochette-Drouin, Olivier; Lévesque, Philippe; Gauvin, Robert; Roberge, Charles J.; Auger, François A.; Goulet, Daniel; Bourdages, Michel; Plante, Michel; Germain, Lucie

2012-01-01

Background After human epidermis wounding, transepithelial potential (TEP) present in nonlesional epidermis decreases and induces an endogenous direct current epithelial electric field (EEF) that could be implicated in the wound re-epithelialization. Some studies suggest that exogenous electric stimulation of wounds can stimulate healing, although the mechanisms remain to be determined. The Problem Little is known concerning the exact action of the EEF during healing. The mechanism responsible for TEP and EEF is unknown due to the lack of an in vitro model to study this phenomenon. Basic Science Advances We carried out studies by using a wound created in a human tissue-engineered skin and determined that TEP undergoes ascending and decreasing phases during the epithelium formation. The in vitro TEP measurements over time in the wound were corroborated with histological changes and with in vivo TEP variations during porcine skin wound healing. The expression of a crucial element implicated in Na+ transport, Na+/K+ ATPase pumps, was also evaluated at the same time points during the re-epithelialization process. The ascending and decreasing TEP values were correlated with changes in the expression of these pumps. The distribution of Na+/K+ ATPase pumps also varied according to epidermal differentiation. Further, inhibition of the pump activity induced a significant decrease of the TEP and of the re-epithelization rate. Clinical Care Relevance A better comprehension of the role of EEF could have important future medical applications regarding the treatment of chronic wound healing. Conclusion This study brings a new perspective to understand the formation and restoration of TEP during the cutaneous wound healing process. PMID:24527285

Pulsations Induced by Vibrations in Aircraft Engine Two-Stage Pump

NASA Astrophysics Data System (ADS)

Gafurov, S. A.; Salmina, V. A.; Handroos, H.

2018-01-01

This paper describes a phenomenon of induced pressure pulsations inside a two-stage aircraft engine pump. A considered pumps consists of a screw-centrifugal and gear stages. The paper describes the cause of two-stage pump elements loading. A number of hypothesis of pressure pulsations generation inside a pump were considered. The main focus in this consideration is made on phenomena that are not related to pump mode of operation. Provided analysis has shown that pump vibrations as well as pump elements self-oscillations are the main causes that lead to trailing vortices generation. Analysis was conducted by means FEM and CFD simulations as well by means of experimental investigations to obtain natural frequencies and flow structure inside a screw-centrifugal stage. To perform accurate simulations adequate boundary conditions were considered. Cavitation and turbulence phenomena have been also taken into account. Obtained results have shown generated trailing vortices lead to high-frequency loading of the impeller of screw-centrifugal stage and can be a cause of the bearing damage.

Shrouded inducer pump

DOEpatents

Meng, S.Y.

1989-08-08

An improvement in a pump is described including a shrouded inducer, the improvement comprising first and second sealing means which cooperate with a first vortex cell and a series of secondary vortex cells to remove any tangential velocity components from the recirculation flow. 3 figs.

Shrouded inducer pump

DOEpatents

Meng, Sen Y.

1989-01-01

An improvement in a pump including a shrouded inducer, the improvement comprising first and second sealing means 32,36 which cooperate with a first vortex cell 38 and a series of secondary vortex cells 40 to remove any tangential velocity components from the recirculation flow.

Rotary Blood Pump

NASA Technical Reports Server (NTRS)

Bozeman, Richard J., Jr. (Inventor); Akkerman, James W. (Inventor); Aber, Gregory S. (Inventor); VanDamm, George A. (Inventor); Bacak, James W. (Inventor); Svejkovsky, Paul A. (Inventor); Benkowski, Robert J. (Inventor)

1996-01-01

A rotary blood pump includes a pump housing for receiving a flow straightener, a rotor mounted on rotor bearings and having an inducer portion and an impeller portion, and a diffuser. The entrance angle, outlet angle, axial and radial clearances of blades associated with the flow straightener, inducer portion, impeller portion and diffuser are optimized to minimize hemolysis while maintaining pump efficiency. The rotor bearing includes a bearing chamber that is filled with cross-linked blood or other bio-compatible material. A back emf integrated circuit regulates rotor operation and a microcomputer may be used to control one or more back emf integrated circuits. A plurality of magnets are disposed in each of a plurality of impeller blades with a small air gap. A stator may be axially adjusted on the pump housing to absorb bearing load and maximize pump efficiency.

Transient enhancement of magnetization damping in CoFeB film via pulsed laser excitation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Bo; Ruan, Xuezhong, E-mail: xzruan@nju.edu.cn, E-mail: ybxu@nju.edu.cn; Wu, Zhenyao

2016-07-25

Laser-induced spin dynamics of in-plane magnetized CoFeB films has been studied by using time-resolved magneto-optical Kerr effect measurements. While the effective demagnetization field shows little dependence on the pump laser fluence, the intrinsic damping constant has been found to be increased from 0.008 to 0.076 with the increase in the pump fluence from 2 mJ/cm{sup 2} to 20 mJ/cm{sup 2}. This sharp enhancement has been shown to be transient and ascribed to the heating effect induced by the pump laser excitation, as the damping constant is almost unchanged when the pump-probe measurements are performed at a fixed pump fluence ofmore » 5 mJ/cm{sup 2} after irradiation by high power pump pulses.« less

Digital multi-channel stabilization of four-mode phase-sensitive parametric multicasting.

PubMed

Liu, Lan; Tong, Zhi; Wiberg, Andreas O J; Kuo, Bill P P; Myslivets, Evgeny; Alic, Nikola; Radic, Stojan

2014-07-28

Stable four-mode phase-sensitive (4MPS) process was investigated as a means to enhance two-pump driven parametric multicasting conversion efficiency (CE) and signal to noise ratio (SNR). Instability of multi-beam, phase sensitive (PS) device that inherently behaves as an interferometer, with output subject to ambient induced fluctuations, was addressed theoretically and experimentally. A new stabilization technique that controls phases of three input waves of the 4MPS multicaster and maximizes CE was developed and described. Stabilization relies on digital phase-locked loop (DPLL) specifically was developed to control pump phases to guarantee stable 4MPS operation that is independent of environmental fluctuations. The technique also controls a single (signal) input phase to optimize the PS-induced improvement of the CE and SNR. The new, continuous-operation DPLL has allowed for fully stabilized PS parametric broadband multicasting, demonstrating CE improvement over 20 signal copies in excess of 10 dB.

Time-resolved SFG study of formate on a Ni( 1 1 1 ) surface under irradiation of picosecond laser pulses

NASA Astrophysics Data System (ADS)

Noguchi, H.; Okada, T.; Onda, K.; Kano, S. S.; Wada, A.; Domen, K.

2003-03-01

Time-resolved sum-frequency generation spectroscopy was carried out on a deuterated formate (DCOO) adsorbed on Ni(1 1 1) surface to investigate the surface reaction dynamics under instantaneous surface temperature jump induced by the irradiation by picosecond laser pulses. The irradiation of pump pulse (800 nm) caused the rapid intensity decrease of both CD and OCO stretching modes of bridged formate on Ni(1 1 1). Different temporal behaviors of intensity recovery between these two vibrational modes were observed, i.e., CD stretching mode recovered faster than OCO. This is the first result to show that the dynamics of adsorbates on metals strongly depends on the observed vibrational mode. From the results of temperature and pump fluence dependence, we concluded that the observed intensity change was not due to the decomposition or desorption, but was induced by a non-thermal process.

Light energy conservation processes in Halobacterium halobium cells

NASA Technical Reports Server (NTRS)

Bogomolni, R. A.

1977-01-01

Proton pumping driven by light or by respiration generates an electrochemical potential difference across the membrane in Halobacterium halobium. The pH changes induced by light or by respiration in cell suspensions are complicated by proton flows associated with the functioning of the cellular energy transducers. A proton-per-ATP ratio of about 3 is calculated from simultaneous measurements of phosphorylation and the proton inflow. This value is compatible with the chemiosmotic coupling hypothesis. The time course of the light-induced changes in membrane potential indicates that light-driven pumping increases a dark pre-existing potential of about 130 mV only by a small amount (20 to 30 mV). The complex kinetic features of the membrane potential changes do not closely follow those of the pH changes, which suggests that flows of ions other than protons are involved. A qualitative model consistent with the available data is presented.

Dynamics of femtosecond laser-induced periodic surface structures on silicon by high spatial and temporal resolution imaging

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jia, X., E-mail: jiaxin@sdju.edu.cn; Department of Mathematics and Physics, Shanghai Dianji University, Shanghai 201306; Jia, T. Q., E-mail: tqjia@phy.ecnu.edu.cn

2014-04-14

The formation dynamics of periodic ripples induced by femtosecond laser pulses (pulse duration τ = 50 fs and central wavelength λ = 800 nm) are studied by a collinear pump-probe imaging technique with a temporal resolution of 1 ps and a spatial resolution of 440 nm. The ripples with periods close to the laser wavelength begin to appear upon irradiation of two pump pulses at surface defects produced by the prior one. The rudiments of periodic ripples emerge in the initial tens of picoseconds after fs laser irradiation, and the ripple positions keep unmoved until the formation processes complete mainly in a temporal span of 1500 ps. Themore » results suggest that the periodic deposition of laser energy during the interaction between femtosecond laser pulses and sample surface plays a dominant role in the formation of periodic ripples.« less

Rogue waves in a multistable system.

PubMed

Pisarchik, Alexander N; Jaimes-Reátegui, Rider; Sevilla-Escoboza, Ricardo; Huerta-Cuellar, G; Taki, Majid

2011-12-30

Clear evidence of rogue waves in a multistable system is revealed by experiments with an erbium-doped fiber laser driven by harmonic pump modulation. The mechanism for the rogue wave formation lies in the interplay of stochastic processes with multistable deterministic dynamics. Low-frequency noise applied to a diode pump current induces rare jumps to coexisting subharmonic states with high-amplitude pulses perceived as rogue waves. The probability of these events depends on the noise filtered frequency and grows up when the noise amplitude increases. The probability distribution of spike amplitudes confirms the rogue wave character of the observed phenomenon. The results of numerical simulations are in good agreement with experiments.

Tricuspid valve excision using off-pump inflow occlusion technique: role of intra-operative trans-esophageal echocardiography.

PubMed

Gadhinglajkar, Shrinivas; Sreedhar, Rupa; Karunakaran, Jayakumar; Misra, Manoranjan; Somasundaram, Ganesh; Mathew, Thomas

2010-01-01

A pacing system infection may lead to infective endocarditis and systemic sepsis. Tricuspid valve surgery may be required if the valve is severely damaged in the process of endocarditis. Although, cardiopulmonary bypass is the safe choice for performing right-heart procedures, it may carry risk of inducing systemic inflammatory response and multi-organ dysfunction. Some studies have advocated TV surgery without institution of CPB. We report tricuspid valve excision using the off-pump inflow occlusion technique in a 68-year-old man. We also describe role of intra-operative TEE as a monitoring tool at different stages of the surgical procedure.

High-resolution multiphoton microscopy with a low-power continuous wave laser pump.

PubMed

Chen, Xiang-Dong; Li, Shen; Du, Bo; Dong, Yang; Wang, Ze-Hao; Guo, Guang-Can; Sun, Fang-Wen

2018-02-15

Multiphoton microscopy (MPM) has been widely used for three-dimensional biological imaging. Here, based on the photon-induced charge state conversion process, we demonstrated a low-power high-resolution MPM with a nitrogen vacancy (NV) center in diamond. Continuous wave green and orange lasers were used to pump and detect the two-photon charge state conversion, respectively. The power of the laser for multiphoton excitation was 40 μW. Both the axial and lateral resolutions were improved approximately 1.5 times compared with confocal microscopy. The results can be used to improve the resolution of the NV center-based quantum sensing and biological imaging.

Theoretical study of optical pump process in solid gain medium based on four-energy-level model

NASA Astrophysics Data System (ADS)

Ma, Yongjun; Fan, Zhongwei; Zhang, Bin; Yu, Jin; Zhang, Hongbo

2018-04-01

A semiclassical algorithm is explored to a four-energy level model, aiming to find out the factors that affect the dynamics behavior during the pump process. The impacts of pump intensity Ω p , non-radiative transition rate γ 43 and decay rate of electric dipole δ 14 are discussed in detail. The calculation results show that large γ 43, small δ 14, and strong pumping Ω p are beneficial to the establishing of population inversion. Under strong pumping conditions, the entire pump process can be divided into four different phases, tentatively named far-from-equilibrium process, Rabi oscillation process, quasi dynamic equilibrium process and ‘equilibrium’ process. The Rabi oscillation can slow the pumping process and cause some instability. Moreover, the duration of the entire process is negatively related to Ω p and γ 43 whereas positively related to δ 14.

Biotic Control of Surface pH and Evidence of Light-Induced H+ Pumping and Ca2+-H+ Exchange in a Tropical Crustose Coralline Alga.

PubMed

Hofmann, Laurie C; Koch, Marguerite; de Beer, Dirk

2016-01-01

Presently, an incomplete mechanistic understanding of tropical reef macroalgae photosynthesis and calcification restricts predictions of how these important autotrophs will respond to global change. Therefore, we investigated the mechanistic link between inorganic carbon uptake pathways, photosynthesis and calcification in a tropical crustose coralline alga (CCA) using microsensors. We measured pH, oxygen (O2), and calcium (Ca2+) dynamics and fluxes at the thallus surface under ambient (8.1) and low (7.8) seawater pH (pHSW) and across a range of irradiances. Acetazolamide (AZ) was used to inhibit extracellular carbonic anhydrase (CAext), which mediates hydrolysis of HCO3-, and 4,4' diisothiocyanatostilbene-2,2'-disulphonate (DIDS) that blocks direct HCO3- uptake by anion exchange transport. Both inhibited photosynthesis, suggesting both diffusive uptake of CO2 via HCO3- hydrolysis to CO2 and direct HCO3- ion transport are important in this CCA. Surface pH was raised approximately 0.3 units at saturating irradiance, but less when CAext was inhibited. Surface pH was lower at pHSW 7.8 than pHSW 8.1 in the dark, but not in the light. The Ca2+ fluxes were large, complex and temporally variable, but revealed net Ca2+ uptake under all conditions. The temporal variability in Ca2+ dynamics was potentially related to localized dissolution during epithallial cell sloughing, a strategy of CCA to remove epiphytes. Simultaneous Ca2+ and pH dynamics suggest the presence of Ca2+/H+ exchange. Rapid light-induced H+ surface dynamics that continued after inhibition of photosynthesis revealed the presence of a light-mediated, but photosynthesis-independent, proton pump. Thus, the study indicates metabolic control of surface pH can occur in CCA through photosynthesis and light-inducible H+ pumps. Our results suggest that complex light-induced ion pumps play an important role in biological processes related to inorganic carbon uptake and calcification in CCA.

Biotic Control of Surface pH and Evidence of Light-Induced H+ Pumping and Ca2+-H+ Exchange in a Tropical Crustose Coralline Alga

PubMed Central

Hofmann, Laurie C.; Koch, Marguerite; de Beer, Dirk

2016-01-01

Presently, an incomplete mechanistic understanding of tropical reef macroalgae photosynthesis and calcification restricts predictions of how these important autotrophs will respond to global change. Therefore, we investigated the mechanistic link between inorganic carbon uptake pathways, photosynthesis and calcification in a tropical crustose coralline alga (CCA) using microsensors. We measured pH, oxygen (O2), and calcium (Ca2+) dynamics and fluxes at the thallus surface under ambient (8.1) and low (7.8) seawater pH (pHSW) and across a range of irradiances. Acetazolamide (AZ) was used to inhibit extracellular carbonic anhydrase (CAext), which mediates hydrolysis of HCO3-, and 4,4′ diisothiocyanatostilbene-2,2′-disulphonate (DIDS) that blocks direct HCO3- uptake by anion exchange transport. Both inhibited photosynthesis, suggesting both diffusive uptake of CO2 via HCO3- hydrolysis to CO2 and direct HCO3- ion transport are important in this CCA. Surface pH was raised approximately 0.3 units at saturating irradiance, but less when CAext was inhibited. Surface pH was lower at pHSW 7.8 than pHSW 8.1 in the dark, but not in the light. The Ca2+ fluxes were large, complex and temporally variable, but revealed net Ca2+ uptake under all conditions. The temporal variability in Ca2+ dynamics was potentially related to localized dissolution during epithallial cell sloughing, a strategy of CCA to remove epiphytes. Simultaneous Ca2+ and pH dynamics suggest the presence of Ca2+/H+ exchange. Rapid light-induced H+ surface dynamics that continued after inhibition of photosynthesis revealed the presence of a light-mediated, but photosynthesis-independent, proton pump. Thus, the study indicates metabolic control of surface pH can occur in CCA through photosynthesis and light-inducible H+ pumps. Our results suggest that complex light-induced ion pumps play an important role in biological processes related to inorganic carbon uptake and calcification in CCA. PMID:27459463

Estimating Hydraulic Parameters When Poroelastic Effects Are Significant

USGS Publications Warehouse

Berg, S.J.; Hsieh, P.A.; Illman, W.A.

2011-01-01

For almost 80 years, deformation-induced head changes caused by poroelastic effects have been observed during pumping tests in multilayered aquifer-aquitard systems. As water in the aquifer is released from compressive storage during pumping, the aquifer is deformed both in the horizontal and vertical directions. This deformation in the pumped aquifer causes deformation in the adjacent layers, resulting in changes in pore pressure that may produce drawdown curves that differ significantly from those predicted by traditional groundwater theory. Although these deformation-induced head changes have been analyzed in several studies by poroelasticity theory, there are at present no practical guidelines for the interpretation of pumping test data influenced by these effects. To investigate the impact that poroelastic effects during pumping tests have on the estimation of hydraulic parameters, we generate synthetic data for three different aquifer-aquitard settings using a poroelasticity model, and then analyze the synthetic data using type curves and parameter estimation techniques, both of which are based on traditional groundwater theory and do not account for poroelastic effects. Results show that even when poroelastic effects result in significant deformation-induced head changes, it is possible to obtain reasonable estimates of hydraulic parameters using methods based on traditional groundwater theory, as long as pumping is sufficiently long so that deformation-induced effects have largely dissipated. ?? 2011 The Author(s). Journal compilation ?? 2011 National Ground Water Association.

Field-effect Flow Control in Polymer Microchannel Networks

NASA Technical Reports Server (NTRS)

Sniadecki, Nathan; Lee, Cheng S.; Beamesderfer, Mike; DeVoe, Don L.

2003-01-01

A new Bio-MEMS electroosmotic flow (EOF) modulator for plastic microchannel networks has been developed. The EOF modulator uses field-effect flow control (FEFC) to adjust the zeta potential at the Parylene C microchannel wall. By setting a differential EOF pumping rate in two of the three microchannels at a T-intersection with EOF modulators, the induced pressure at the intersection generated pumping in the third, field-free microchannel. The EOF modulators are able to change the magnitude and direction of the pressure pumping by inducing either a negative or positive pressure at the intersection. The flow velocity is tracked by neutralized fluorescent microbeads in the microchannels. The proof-of-concept of the EOF modulator described here may be applied to complex plastic ,microchannel networks where individual microchannel flow rates are addressable by localized induced-pressure pumping.

Analysis and Modeling of a Two-Phase Jet Pump of a Thermal Management System for Aerospace Applications

NASA Technical Reports Server (NTRS)

Sherif, S.A.; Hunt, P. L.; Holladay, J. B.; Lear, W. E.; Steadham, J. M.

1998-01-01

Jet pumps are devices capable of pumping fluids to a higher pressure by inducing the motion of a secondary fluid employing a high speed primary fluid. The main components of a jet pump are a primary nozzle, secondary fluid injectors, a mixing chamber, a throat, and a diffuser. The work described in this paper models the flow of a two-phase primary fluid inducing a secondary liquid (saturated or subcooled) injected into the jet pump mixing chamber. The model is capable of accounting for phase transformations due to compression, expansion, and mixing. The model is also capable of incorporating the effects of the temperature and pressure dependency in the analysis. The approach adopted utilizes an isentropic constant pressure mixing in the mixing chamber and at times employs iterative techniques to determine the flow conditions in the different parts of the jet pump.

46 CFR 111.103-9 - Machinery stop stations.

Code of Federal Regulations, 2011 CFR

2011-10-01

... fan, induced draft fan, blower of an inert gas system, fuel oil transfer pump, fuel oil unit, fuel oil service pump, and any other fuel oil pumps must have a stop control that is outside of the space containing the pump or fan. (b) Each stop control must meet § 111.103-7. ...

46 CFR 58.01-25 - Means of stopping machinery.

Code of Federal Regulations, 2014 CFR

2014-10-01

... forced-draft and induced-draft fans, fuel-oil transfer pumps, fuel-oil unit and service pumps, and similar fuel-oil pumps must be fitted with remote controls from a readily accessible position outside the space concerned so that the fans or pumps may be stopped in case of fire in the compartment in which...

46 CFR 111.103-9 - Machinery stop stations.

Code of Federal Regulations, 2012 CFR

2012-10-01

... fan, induced draft fan, blower of an inert gas system, fuel oil transfer pump, fuel oil unit, fuel oil service pump, and any other fuel oil pumps must have a stop control that is outside of the space containing the pump or fan. (b) Each stop control must meet § 111.103-7. ...

46 CFR 111.103-9 - Machinery stop stations.

Code of Federal Regulations, 2014 CFR

2014-10-01

... fan, induced draft fan, blower of an inert gas system, fuel oil transfer pump, fuel oil unit, fuel oil service pump, and any other fuel oil pumps must have a stop control that is outside of the space containing the pump or fan. (b) Each stop control must meet § 111.103-7. ...

46 CFR 111.103-9 - Machinery stop stations.

Code of Federal Regulations, 2013 CFR

2013-10-01

... fan, induced draft fan, blower of an inert gas system, fuel oil transfer pump, fuel oil unit, fuel oil service pump, and any other fuel oil pumps must have a stop control that is outside of the space containing the pump or fan. (b) Each stop control must meet § 111.103-7. ...

46 CFR 58.01-25 - Means of stopping machinery.

Code of Federal Regulations, 2013 CFR

2013-10-01

... forced-draft and induced-draft fans, fuel-oil transfer pumps, fuel-oil unit and service pumps, and similar fuel-oil pumps must be fitted with remote controls from a readily accessible position outside the space concerned so that the fans or pumps may be stopped in case of fire in the compartment in which...

46 CFR 58.01-25 - Means of stopping machinery.

Code of Federal Regulations, 2011 CFR

2011-10-01

... forced-draft and induced-draft fans, fuel-oil transfer pumps, fuel-oil unit and service pumps, and similar fuel-oil pumps must be fitted with remote controls from a readily accessible position outside the space concerned so that the fans or pumps may be stopped in case of fire in the compartment in which...

46 CFR 58.01-25 - Means of stopping machinery.

Code of Federal Regulations, 2012 CFR

2012-10-01

... forced-draft and induced-draft fans, fuel-oil transfer pumps, fuel-oil unit and service pumps, and similar fuel-oil pumps must be fitted with remote controls from a readily accessible position outside the space concerned so that the fans or pumps may be stopped in case of fire in the compartment in which...

46 CFR 111.103-9 - Machinery stop stations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... fan, induced draft fan, blower of an inert gas system, fuel oil transfer pump, fuel oil unit, fuel oil service pump, and any other fuel oil pumps must have a stop control that is outside of the space containing the pump or fan. (b) Each stop control must meet § 111.103-7. ...

Femtosecond pulsed laser processing of electronic materials: Fundamentals and micro/nano-scale applications

NASA Astrophysics Data System (ADS)

Choi, Tae-Youl

Ultra-short pulsed laser radiation has been shown to be effective for precision materials processing and surface micro-modification. One of advantages is the substantial reduction of the heat penetration depth, which leads to minimal lateral damage. Other advantages include non-thermal nature of ablation process, controlled ablation and ideal characteristics for precision micro-structuring. Yet, fundamental questions remain unsolved regarding the nature of melting and ablation mechanisms in femtosecond laser processing of materials. In addition to micro engineering problems, nano-structuring and nano-fabrication are emerging fields that are of particular interest in conjunction with femtosecond laser processing. A comprehensive experimental study as well as theoretical development is presented to address these issues. Ultra-short pulsed laser irradiation was used to crystallize 100 nm amorphous silicon (a-Si) films. The crystallization process was observed by time-resolved pump-and-probe reflection imaging in the range of 0.2 ps to 100 ns. The in-situ images in conjunction with post-processed SEM and AFM mapping of the crystallized structure provide evidence for non-thermal ultra-fast phase transition and subsequent surface-initiated crystallization. Mechanisms of ultra-fast laser-induced ablation on crystalline silicon and copper are investigated by time-resolved pump-and-probe microscopy in normal imaging and shadowgraph arrangements. A one-dimensional model of the energy transport is utilized to predict the carrier temperature and lattice temperature as well as the electron and vapor flux emitted from the surface. The temporal delay between the pump and probe pulses was set by a precision translation stage up to about 500 ps and then extended to the nanosecond regime by an optical fiber assembly. The ejection of material was observed at several picoseconds to tens of nanoseconds after the main (pump) pulse by high-resolution, ultra-fast shadowgraphs. The ultrashort laser pulse accompanied by the pre-pulse induces air breakdown that can be detrimental to materials processing. A time-resolved pump-and-probe experiment provides distinct evidence for the occurrence of an air plasma and air breakdown. This highly nonlinear phenomenon takes place before the commencement of the ablation process, which is traced beyond elapsed time of the order of 10 ps with respect to the ablating pulse. The nonlinear refractive index of the generated air plasma is calculated as a function of electron density. The self-focusing of the main pulse is identified by the third order nonlinear susceptibility. A crystalline silicon sample is subjected to two optically separated ultra-fast laser pulses of full-width-half-maximum (FWHM) duration of about 80 femtoseconds. These pulses are delivered at wavelength, lambda = 800 nm. Femtosecond-resolved imaging pump-and-probe experiments in reflective and Schlieren configurations have been performed to investigate plasma dynamics and shock wave propagation during the sample ablation process. By using a diffractive optical element (DOE) for beam shaping, microchannels were fabricated. A super-long working distance objective lens was used to machine silicon materials in the sub-micrometer scale. As an extension of micro-machining, the finite difference time domain (FDTD) method is used to assess the feasibility of using near-field distribution of laser light. Gold coated films were machined with nano-scale dimensions and characterized with atomic force microscopy (AFM).

Inducer analysis/pump model development

NASA Astrophysics Data System (ADS)

Cheng, Gary C.

1994-03-01

Current design of high performance turbopumps for rocket engines requires effective and robust analytical tools to provide design information in a productive manner. The main goal of this study was to develop a robust and effective computational fluid dynamics (CFD) pump model for general turbopump design and analysis applications. A finite difference Navier-Stokes flow solver, FDNS, which includes an extended k-epsilon turbulence model and appropriate moving zonal interface boundary conditions, was developed to analyze turbulent flows in turbomachinery devices. In the present study, three key components of the turbopump, the inducer, impeller, and diffuser, were investigated by the proposed pump model, and the numerical results were benchmarked by the experimental data provided by Rocketdyne. For the numerical calculation of inducer flows with tip clearance, the turbulence model and grid spacing are very important. Meanwhile, the development of the cross-stream secondary flow, generated by curved blade passage and the flow through tip leakage, has a strong effect on the inducer flow. Hence, the prediction of the inducer performance critically depends on whether the numerical scheme of the pump model can simulate the secondary flow pattern accurately or not. The impeller and diffuser, however, are dominated by pressure-driven flows such that the effects of turbulence model and grid spacing (except near leading and trailing edges of blades) are less sensitive. The present CFD pump model has been proved to be an efficient and robust analytical tool for pump design due to its very compact numerical structure (requiring small memory), fast turnaround computing time, and versatility for different geometries.

Inducer analysis/pump model development

NASA Technical Reports Server (NTRS)

Cheng, Gary C.

1994-01-01

Current design of high performance turbopumps for rocket engines requires effective and robust analytical tools to provide design information in a productive manner. The main goal of this study was to develop a robust and effective computational fluid dynamics (CFD) pump model for general turbopump design and analysis applications. A finite difference Navier-Stokes flow solver, FDNS, which includes an extended k-epsilon turbulence model and appropriate moving zonal interface boundary conditions, was developed to analyze turbulent flows in turbomachinery devices. In the present study, three key components of the turbopump, the inducer, impeller, and diffuser, were investigated by the proposed pump model, and the numerical results were benchmarked by the experimental data provided by Rocketdyne. For the numerical calculation of inducer flows with tip clearance, the turbulence model and grid spacing are very important. Meanwhile, the development of the cross-stream secondary flow, generated by curved blade passage and the flow through tip leakage, has a strong effect on the inducer flow. Hence, the prediction of the inducer performance critically depends on whether the numerical scheme of the pump model can simulate the secondary flow pattern accurately or not. The impeller and diffuser, however, are dominated by pressure-driven flows such that the effects of turbulence model and grid spacing (except near leading and trailing edges of blades) are less sensitive. The present CFD pump model has been proved to be an efficient and robust analytical tool for pump design due to its very compact numerical structure (requiring small memory), fast turnaround computing time, and versatility for different geometries.

Stimulation of the cardiac myocyte Na+-K+ pump due to reversal of its constitutive oxidative inhibition

PubMed Central

Chia, Karin K. M.; Liu, Chia-Chi; Hamilton, Elisha J.; Garcia, Alvaro; Fry, Natasha A.; Hannam, William; Figtree, Gemma A.

2015-01-01

Protein kinase C can activate NADPH oxidase and induce glutathionylation of the β1-Na+-K+ pump subunit, inhibiting activity of the catalytic α-subunit. To examine if signaling of nitric oxide-induced soluble guanylyl cyclase (sGC)/cGMP/protein kinase G can cause Na+-K+ pump stimulation by counteracting PKC/NADPH oxidase-dependent inhibition, cardiac myocytes were exposed to ANG II to activate NADPH oxidase and inhibit Na+-K+ pump current (Ip). Coexposure to 3-(5′-hydroxymethyl-2′-furyl)-1-benzylindazole (YC-1) to stimulate sGC prevented the decrease of Ip. Prevention of the decrease was abolished by inhibition of protein phosphatases (PP) 2A but not by inhibition of PP1, and it was reproduced by an activator of PP2A. Consistent with a reciprocal relationship between β1-Na+-K+ pump subunit glutathionylation and pump activity, YC-1 decreased ANG II-induced β1-subunit glutathionylation. The decrease induced by YC-1 was abolished by a PP2A inhibitor. YC-1 decreased phosphorylation of the cytosolic p47phox NADPH oxidase subunit and its coimmunoprecipitation with the membranous p22phox subunit, and it decreased O2·−-sensitive dihydroethidium fluorescence of myocytes. Addition of recombinant PP2A to myocyte lysate decreased phosphorylation of p47phox indicating the subunit could be a substrate for PP2A. The effects of YC-1 to decrease coimmunoprecipitation of p22phox and p47phox NADPH oxidase subunits and decrease β1-Na+-K+ pump subunit glutathionylation were reproduced by activation of nitric oxide-dependent receptor signaling. We conclude that sGC activation in cardiac myocytes causes a PP2A-dependent decrease in NADPH oxidase activity and a decrease in β1 pump subunit glutathionylation. This could account for pump stimulation with neurohormonal oxidative stress expected in vivo. PMID:26084308

Hydraulic and Thermal Response to Intermittent Pumping in Unconfined Alluvial Aquifers along a Regulated Stream

NASA Astrophysics Data System (ADS)

Maharjan, Madan

Groundwater response to stream stage fluctuations was studied using a year-long time series of stream stage and well heads in Glen Dale and New Martinsville, WV. Stream stage fluctuations exerted primary control over groundwater levels, especially during high flows. The location and operation of river pools created by dams alter groundwater flow paths and velocities. Aquifers are more prone to surface water infiltration in the upper reaches of pools than in lower reaches. Aquifer diffusivity is heterogeneous within and between the two sites. Temperature fluctuations were observed for 2.5 years in 14 wells in three alluvial aquifers. Temperature signals have 2 components corresponding to pump-on and pump-off periods. Both components vary seasonality at different magnitudes. While pump-off temperatures fluctuated up to 3.8o C seasonally, short-term temperature shifts induced by turning the pump on were 0.2 to 2.5o C. Pumping-induced temperature shifts were highest in magnitude in summer and winter. Groundwater temperature lagged behind that of surface water by approximately six months. Pumping induced and seasonal temperature shifts were spatially and temporally complex but indicate stream exfiltration is a major driver for a number of these wells. Numerical simulation of aquifer response to pumping show different conditions before and after well-field development. During pre-development, the stream was losing at high flow and gaining at low flow. During post-development, however, the stream was losing at high flow and spatially variable at low flow. While bank storage gained only during high stage, stream exfiltration occurred year-round. Pumping induced stream exfiltration by creating an extensive cone of depression beneath the stream in both upstream and downstream directions. Spatially and temporally variable groundwater-surface water interaction next to a regulated stream were studied using analytical and numerical models, based on field observations. Seasonality plays an important role in these interactions, but human activity may also alter its intensity.

An Adoptive Mother Who Became a Human Milk Donor.

PubMed

Flores-Antón, Beatriz; García-Lara, Nadia Raquel; Pallás-Alonso, Carmen Rosa

2017-05-01

Inducing lactation in the absence of pregnancy (nonpuerperal lactation) is not always successful and, in many cases, only partial breastfeeding is achieved. Different protocols have been described, but scientific evidence and research are lacking in this area. The authors describe the case of a woman with a history of a miscarriage, for whom the lactation induction process was so effective that she became a milk donor even before she received her adopted child. She had not previously used hormone treatment. She was given domperidone as a galactogogue for 1 month. The pumping protocol began with a double electric breast pump combined with manual pumping 6 months before her child was delivered, and 3 months later, she was accepted as a donor by our milk bank. This highlights the importance of regular stimulation as a milk production mechanism. This is the first case of human milk donation in an adoptive mother described in the literature.

Ultrafast Coulomb-Induced Intervalley Coupling in Atomically Thin WS2.

PubMed

Schmidt, Robert; Berghäuser, Gunnar; Schneider, Robert; Selig, Malte; Tonndorf, Philipp; Malić, Ermin; Knorr, Andreas; Michaelis de Vasconcellos, Steffen; Bratschitsch, Rudolf

2016-05-11

Monolayers of semiconducting transition metal dichalcogenides hold the promise for a new paradigm in electronics by exploiting the valley degree of freedom in addition to charge and spin. For MoS2, WS2, and WSe2, valley polarization can be conveniently initialized and read out by circularly polarized light. However, the underlying microscopic processes governing valley polarization in these atomically thin equivalents of graphene are still not fully understood. Here, we present a joint experiment-theory study on the ultrafast time-resolved intervalley dynamics in monolayer WS2. Based on a microscopic theory, we reveal the many-particle mechanisms behind the observed spectral features. We show that Coulomb-induced intervalley coupling explains the immediate and prominent pump-probe signal in the unpumped valley and the seemingly low valley polarization degrees typically observed in pump-probe measurements compared to photoluminescence studies. The gained insights are also applicable to other light-emitting monolayer transition metal dichalcogenides, such as MoS2 and WSe2, where the Coulomb-induced intervalley coupling also determines the initial carrier dynamics.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Erickson III, David J.; Sulzberger, Barbara; Zepp, Richard G.

Climate change modulates the effects of solar UV radiation on biogeochemical cycles in terrestrial and aquatic ecosystems, particularly for carbon cycling, resulting in UV-mediated positive or negative feedbacks on climate. Possible positive feedbacks discussed in this assessment include: (i) enhanced UV-induced mineralisation of above ground litter due to aridification; (ii) enhanced UV-induced mineralisation of photoreactive dissolved organic matter (DOM) in aquatic ecosystems due to changes in continental runoff and ice melting; (iii) reduced efficiency of the biological pump due to UV-induced bleaching of coloured dissolved organic matter (CDOM) in stratified aquatic ecosystems, where CDOM protects phytoplankton from the damaging solarmore » UV-B radiation. Mineralisation of organic matter results in the production and release of CO 2, whereas the biological pump is the main biological process for CO 2 removal by aquatic ecosystems. This research also assesses the interactive effects of solar UV radiation and climate change on the biogeochemical cycling of aerosols and trace gases other than CO 2, as well as of chemical and biological contaminants. Lastly,, interacting effects of solar UV radiation and climate change on biogeochemical cycles are particularly pronounced at terrestrial-aquatic interfaces.« less

46 CFR 58.01-25 - Means of stopping machinery.

Code of Federal Regulations, 2010 CFR

2010-10-01

... forced-draft and induced-draft fans, fuel-oil transfer pumps, fuel-oil unit and service pumps, and... space concerned so that the fans or pumps may be stopped in case of fire in the compartment in which...

Mid-infrared picosecond pump-dump-probe and pump-repump-probe experiments to resolve a ground-state intermediate in cyanobacterial phytochrome Cph1.

PubMed

van Wilderen, Luuk J G W; Clark, Ian P; Towrie, Michael; van Thor, Jasper J

2009-12-24

Multipulse picosecond mid-infrared spectroscopy has been used to study photochemical reactions of the cyanobacterial phytochrome photoreceptor Cph1. Different photophysical schemes have been discussed in the literature to describe the pathways after photoexcitation, particularly, to identify reaction phases that are linked to photoisomerisation and electronic decay in the 1566-1772 cm(-1) region that probes C=C and C=O stretching modes of the tetrapyrrole chromophore. Here, multipulse spectroscopy is employed, where, compared to conventional visible pump-mid-infrared probe spectroscopy, an additional visible pulse is incorporated that interacts with populations that are evolving on the excited- and ground-state potential energy surfaces. The time delays between the pump and the dump pulse are chosen such that the dump pulse interacts with different phases in the reaction process. The pump and dump pulses are at the same wavelength, 640 nm, and are resonant with the Pr ground state as well as with the excited state and intermediates. Because the dump pulse additionally pumps the remaining, partially recovered, and partially oriented ground-state population, theory is developed for estimating the fraction of excited-state molecules. The calculations take into account the model-dependent ground-state recovery fraction, the angular dependence of the population transfer resulting from the finite bleach that occurs with linearly polarized intense femtosecond optical excitation, and the partially oriented population for the dump field. Distinct differences between the results from the experiments that use a 1 or a 14 ps dump time favor a branching evolution from S1 to an excited state or reconfigured chromophore and to a newly identified ground-state intermediate (GSI). Optical dumping at 1 ps shows the instantaneous induced absorption of a delocalized C=C stretching mode at 1608 cm(-1), where the increased cross section is associated with the electronic ground-state structure of the ZZZ configuration of the linear tetrapyrrole chromophore. The dump-induced absorption decays with time constants of 5 and 19 ps to the Pr ground state. Employing a dump pulse at 14 ps results in an instantaneous decrease of the absorption of the 1608 cm(-1) band, indicating repumping of the GSI. The dump-induced absorption recovers back to the GSI with a 6 ps lifetime. A spectral similarity is observed between the 6 ps phase in the dump experiment and the 3 ps component found in the two-pulse pump-probe measurement. Combined with the dominance of ground-state absorption bands in the dump-induced spectrum, this indicates the presence of a GSI, which is additionally characterized by previously unidentified induced absorption at 1710 and 1570-80 cm(-1). The metastable photoproduct Lumi-R, which is in the electronic ground state and populated at 500 ps after excitation of Pr, is highly efficiently repumped into the Pr ground state with the power density used. After repumping, Lumi-R is not recovered on the 500 ps time scale of the experiment and is distinct from the GSI of Pr since it is not associated with its characteristic induced absorption at 1710 and 1570-80 cm(-1).

The influence of thermal and free carrier dispersion effects on all-optical wavelength conversion in a silicon racetrack-shaped microring resonator

NASA Astrophysics Data System (ADS)

Wang, Zhaolu; Liu, Hongjun; Sun, Qibing; Huang, Nan; Li, Shaopeng; Han, Jing

2016-07-01

We experimentally demonstrate ultra-low pump power wavelength conversion based on four-wave mixing in a silicon racetrack-shaped microring resonator. When the pump and signal are located at the resonance wavelengths, wavelength conversion with a pump power of only 1 mW can be realized in this microring resonator because of the resonant enhancement of the device. However, saturation of the conversion efficiency occurs because of the shift of the resonance peak, which is caused by the change of the effective refractive index induced by a combination of thermal and free carrier dispersion effects, and it is demonstrated that the thermal effect is the leading-order factor for the change of the refractive index. The maximum conversion efficiency of  -21 dB is obtained when the pump power is less than 12 mW. This ultra-low-power on-chip wavelength convertor based on a silicon microring resonator can find important potential applications in highly integrated optical circuits for all-optical signal processing.

Computation of incompressible viscous flows through turbopump components

NASA Technical Reports Server (NTRS)

Kiris, Cetin; Chang, Leon

1993-01-01

Flow through pump components, such as an inducer and an impeller, is efficiently simulated by solving the incompressible Navier-Stokes equations. The solution method is based on the pseudocompressibility approach and uses an implicit-upwind differencing scheme together with the Gauss-Seidel line relaxation method. the equations are solved in steadily rotating reference frames and the centrifugal force and the Coriolis force are added to the equation of motion. Current computations use a one-equation Baldwin-Barth turbulence model which is derived from a simplified form of the standard k-epsilon model equations. The resulting computer code is applied to the flow analysis inside a generic rocket engine pump inducer, a fuel pump impeller, and SSME high pressure fuel turbopump impeller. Numerical results of inducer flow are compared with experimental measurements. In the fuel pump impeller, the effect of downstream boundary conditions is investigated. Flow analyses at 80 percent, 100 percent, and 120 percent of design conditions are presented.

Power amplification for petawatt Ti: Sapphire lasers: New strategies for high fluence pumping

NASA Astrophysics Data System (ADS)

Canova, F.; Chambaret, J.-P.

2006-06-01

One of the major bottlenecks when we pump large Ti:Sapphire crystals, to reach Petawatt level laser amplification, is the careful control of the spatial energy distribution of Nd:Glass pump lasers. Commercially available nanosecond Nd:Glass and Nd:YAG lasers exhibit poor spatial profile quality especially in the near and in the intermediate field, which can lead to local hot spots, responsible of damages in crystals, and parasitic transverse lasing enhancement, strongly dependent on the profile of the pump beam . For these reasons, it is mandatory to keep the pump beam intensity profile as flat as possible on the pumped crystal. To guarantee the best pumping conditions we are investigating the combined use of DOE (diffractive optical elements) and optical smoothing techniques. In parallel we are starting a study on laser induced damages mechanisms in crystal. With DOE and microlens arrays we plan to guarantee to the beam a supergaussian shape. Simulation and first experiments with both optical systems show that a flat top spatial profile with less than 10% fluctuations and a 8th order supergaussian is possible with the present technology.Optical smoothing will keep the beam free of hot spots. We especially focused on the smoothing techniques involving optical fibers. This is the first time to our knowledge that this technique is applied to the pumping beams for Ti:Sapphire systems. A deep study of laser-crystal interaction will allow us to fully understand the damages created by hot spots. The knowledge of the phenomena involved in laser damages on Ti:Sapphire is mandatory to control the pumping processes and thresholds. In conclusion, mixing the advantages of these different approaches to overcome this bottleneck will allow us to amplify in a safety way femtosecond laser beams to the Petawatt level using Ti:Sapphire crystals.

Study of Anti-Vortex Baffle Effect in Suppressing Swirling Flow in LOX Tank

NASA Technical Reports Server (NTRS)

Yang, H. Q.; Peugeot, John

2011-01-01

Experimental results describing the hydraulic dynamic pump transfer matrix (Yp) for a cavitating J-2X oxidizer turbopump inducer+impeller tested in subscale waterflow are presented. The transfer function is required for integrated vehicle pogo stability analysis as well as optimization of local inducer pumping stability. Dynamic transfer functions across widely varying pump hydrodynamic inlet conditions are extracted from measured data in conjunction with 1D-model based corrections. Derived Dynamic transfer functions are initially interpreted relative to traditional Pogo pump equations. Water-to-liquid oxygen scaling of measured cavitation characteristics are discussed. Comparison of key dynamic transfer matrix terms derived from waterflow testing are made with those implemented in preliminary Ares Upper Stage Pogo stability modeling. Alternate cavitating pump hydraulic dynamic equations are suggested which better reflect frequency dependencies of measured transfer matrices.

Sensitivity of Proposed Search for Axion-induced Magnetic Field using Optically Pumped Magnetometers

DOE PAGES

Chu, Pinghan; Duffy, Leanne Delma; Kim, Young Jin; ...

2018-04-17

We investigate the sensitivity of a search for the oscillating current induced by axion dark matter in an external magnetic field using optically pumped magnetometers. This experiment is based upon the LC circuit (circuit with inductor and capacitor) axion detection concept of Sikivie et al. [Phys. Rev. Lett. 112, 131301 (2014)]. The modification of Maxwell’s equations caused by the axion-photon coupling results in a minute magnetic field oscillating at a frequency equal to the axion mass, in the presence of an external magnetic field. The axion-induced magnetic field could be searched for using a LC circuit amplifier with an opticallymore » pumped magnetometer, the most sensitive cryogen-free magnetic-field sensor, in a room-temperature experiment, avoiding the need for a complicated and expensive cryogenic system. Here, we discuss how an existing magnetic resonance imaging experiment can be modified to search for axions in a previously unexplored part of the parameter space. Our existing detection setup, optimized for magnetic resonance imagining, is already sensitive to an axion-photon coupling of 10 -7 GeV -1 for an axion mass near 3 × 10 -10 eV, which is already limited by astrophysical processes and solar axion searches. We show that realistic modifications, and optimization of the experiment for axion detection, can probe the axion-photon coupling up to 4 orders of magnitude beyond the current best limit, for axion masses between 10 -1 and 10 -7 eV.« less

Sensitivity of Proposed Search for Axion-induced Magnetic Field using Optically Pumped Magnetometers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chu, Pinghan; Duffy, Leanne Delma; Kim, Young Jin

We investigate the sensitivity of a search for the oscillating current induced by axion dark matter in an external magnetic field using optically pumped magnetometers. This experiment is based upon the LC circuit (circuit with inductor and capacitor) axion detection concept of Sikivie et al. [Phys. Rev. Lett. 112, 131301 (2014)]. The modification of Maxwell’s equations caused by the axion-photon coupling results in a minute magnetic field oscillating at a frequency equal to the axion mass, in the presence of an external magnetic field. The axion-induced magnetic field could be searched for using a LC circuit amplifier with an opticallymore » pumped magnetometer, the most sensitive cryogen-free magnetic-field sensor, in a room-temperature experiment, avoiding the need for a complicated and expensive cryogenic system. Here, we discuss how an existing magnetic resonance imaging experiment can be modified to search for axions in a previously unexplored part of the parameter space. Our existing detection setup, optimized for magnetic resonance imagining, is already sensitive to an axion-photon coupling of 10 -7 GeV -1 for an axion mass near 3 × 10 -10 eV, which is already limited by astrophysical processes and solar axion searches. We show that realistic modifications, and optimization of the experiment for axion detection, can probe the axion-photon coupling up to 4 orders of magnitude beyond the current best limit, for axion masses between 10 -1 and 10 -7 eV.« less

Sensitivity of proposed search for axion-induced magnetic field using optically pumped magnetometers

NASA Astrophysics Data System (ADS)

Chu, P.-H.; Duffy, L. D.; Kim, Y. J.; Savukov, I. M.

2018-04-01

We investigate the sensitivity of a search for the oscillating current induced by axion dark matter in an external magnetic field using optically pumped magnetometers. This experiment is based upon the LC circuit (circuit with inductor and capacitor) axion detection concept of Sikivie et al. [Phys. Rev. Lett. 112, 131301 (2014), 10.1103/PhysRevLett.112.131301]. The modification of Maxwell's equations caused by the axion-photon coupling results in a minute magnetic field oscillating at a frequency equal to the axion mass, in the presence of an external magnetic field. The axion-induced magnetic field could be searched for using a LC circuit amplifier with an optically pumped magnetometer, the most sensitive cryogen-free magnetic-field sensor, in a room-temperature experiment, avoiding the need for a complicated and expensive cryogenic system. We discuss how an existing magnetic resonance imaging experiment can be modified to search for axions in a previously unexplored part of the parameter space. Our existing detection setup, optimized for magnetic resonance imagining, is already sensitive to an axion-photon coupling of 10-7 GeV-1 for an axion mass near 3 ×10-10 eV , which is already limited by astrophysical processes and solar axion searches. We show that realistic modifications, and optimization of the experiment for axion detection, can probe the axion-photon coupling up to 4 orders of magnitude beyond the current best limit, for axion masses between 10-11 and 10-7 eV .

Selectivity of externally facing ion-binding sites in the Na/K pump to alkali metals and organic cations

PubMed Central

Ratheal, Ian M.; Virgin, Gail K.; Yu, Haibo; Roux, Benoît; Gatto, Craig; Artigas, Pablo

2010-01-01

The Na/K pump is a P-type ATPase that exchanges three intracellular Na+ ions for two extracellular K+ ions through the plasmalemma of nearly all animal cells. The mechanisms involved in cation selection by the pump's ion-binding sites (site I and site II bind either Na+ or K+; site III binds only Na+) are poorly understood. We studied cation selectivity by outward-facing sites (high K+ affinity) of Na/K pumps expressed in Xenopus oocytes, under voltage clamp. Guanidinium+, methylguanidinium+, and aminoguanidinium+ produced two phenomena possibly reflecting actions at site III: (i) voltage-dependent inhibition (VDI) of outwardly directed pump current at saturating K+, and (ii) induction of pump-mediated, guanidinium-derivative–carried inward current at negative potentials without Na+ and K+. In contrast, formamidinium+ and acetamidinium+ induced K+-like outward currents. Measurement of ouabain-sensitive ATPase activity and radiolabeled cation uptake confirmed that these cations are external K+ congeners. Molecular dynamics simulations indicate that bound organic cations induce minor distortion of the binding sites. Among tested metals, only Li+ induced Na+-like VDI, whereas all metals tested except Na+ induced K+-like outward currents. Pump-mediated K+-like organic cation transport challenges the concept of rigid structural models in which ion specificity at site I and site II arises from a precise and unique arrangement of coordinating ligands. Furthermore, actions by guanidinium+ derivatives suggest that Na+ binds to site III in a hydrated form and that the inward current observed without external Na+ and K+ represents cation transport when normal occlusion at sites I and II is impaired. These results provide insights on external ion selectivity at the three binding sites. PMID:20937860

Experimental Determination of the Dynamic Hydraulic Transfer Function for the J-2X Oxidizer Turbopump. Part One; Methodology

NASA Technical Reports Server (NTRS)

Zoladz, Tom; Patel, Sandeep; Lee, Erik; Karon, Dave

2011-01-01

An advanced methodology for extracting the hydraulic dynamic pump transfer matrix (Yp) for a cavitating liquid rocket engine turbopump inducer+impeller has been developed. The transfer function is required for integrated vehicle pogo stability analysis as well as optimization of local inducer pumping stability. Laboratory pulsed subscale waterflow test of the J-2X oxygen turbo pump is introduced and our new extraction method applied to the data collected. From accurate measures of pump inlet and discharge perturbational mass flows and pressures, and one-dimensional flow models that represents complete waterflow loop physics, we are able to derive Yp and hence extract the characteristic pump parameters: compliance, pump gain, impedance, mass flow gain. Detailed modeling is necessary to accurately translate instrument plane measurements to the pump inlet and discharge and extract Yp. We present the MSFC Dynamic Lump Parameter Fluid Model Framework and describe critical dynamic component details. We report on fit minimization techniques, cost (fitness) function derivation, and resulting model fits to our experimental data are presented. Comparisons are made to alternate techniques for spatially translating measurement stations to actual pump inlet and discharge.

Simultaneous mixing and pumping using asymmetric microelectrodes

NASA Astrophysics Data System (ADS)

Kim, Byoung Jae; Yoon, Sang Youl; Sung, Hyung Jin; Smith, Charles G.

2007-10-01

This study proposes ideas for simultaneous mixing and pumping using asymmetric microelectrode arrays. The driving force of the mixing and pumping was based on electroosmotic flows induced by alternating current (ac) electric fields on asymmetric microelectrodes. The key idea was to bend/incline the microelectrodes like diagonal/herringbone shapes. Four patterns of the asymmetric electrode arrays were considered depending on the shape of electrode arrays. For the diagonal shape, repeated and staggered patterns of the electrode arrays were studied. For the herringbone shape, diverging and converging patterns were examined. These microelectrode patterns forced fluid flows in the lateral direction leading to mixing and in the channel direction leading to pumping. Three-dimensional numerical simulations were carried out using the linear theories of ac electro-osmosis. The performances of the mixing and pumping were assessed in terms of the mixing efficiency and the pumping flow rate. The results indicated that the helical flow motions induced by the electrode arrays play a significant role in the mixing enhancement. The pumping performance was influenced by the slip velocity at the center region of the channel compared to that near the side walls.

Exciton Absorption in Semiconductor Quantum Wells Driven by a Strong Intersubband Pump Field

NASA Technical Reports Server (NTRS)

Liu, Ansheng; Ning, Cun-Zheng

1999-01-01

Optical interband excitonic absorption of semiconductor quantum wells (QW's) driven by a coherent pump field is investigated based on semiconductor Bloch equations. The pump field has a photon energy close to the intersubband spacing between the first two conduction subbands in the QW's. An external weak optical field probes the interband transition. The excitonic effects and pump-induced population redistribution within the conduction subbands in the QW system are included. When the density of the electron-hole pairs in the QW structure is low, the pump field induces an Autler-Townes splitting of the exciton absorption spectrum. The split size and the peak positions of the absorption doublet depend not only on the pump frequency and intensity but also on the carrier density. As the density of the electron-hole pairs is increased, the split contrast (the ratio between the maximum and minimum values) is decreased because the exciton effect is suppressed at higher densities due to the many-body screening.

Investigating radiation induced damage processes with femtosecond x-ray pulses (Conference Presentation)

NASA Astrophysics Data System (ADS)

Song, Changyong

2017-05-01

Interest in high-resolution structure investigation has been zealous, especially with the advent of X-ray free electron lasers (XFELs). The intense and ultra-short X-ray laser pulses ( 10 GW) pave new routes to explore structures and dynamics of single macromolecules, functional nanomaterials and complex electronic materials. In the last several years, we have developed XFEL single-shot diffraction imaging by probing ultrafast phase changes directly. Pump-probe single-shot imaging was realized by synchronizing femtosecond (<10 fs in FWHM) X-ray laser (probe) with femtosecond (50 fs) IR laser (pump) at better than 1 ps resolution. Nanoparticles under intense fs-laser pulses were investigated with fs XFEL pulses to provide insight into the irreversible particle damage processes with nanoscale resolution. Research effort, introduced, aims to extend the current spatio-temporal resolution beyond the present limit. We expect this single-shot dynamic imaging to open new science opportunity with XFELs.

Water pumping in mantle shear zones

PubMed Central

Précigout, Jacques; Prigent, Cécile; Palasse, Laurie; Pochon, Anthony

2017-01-01

Water plays an important role in geological processes. Providing constraints on what may influence the distribution of aqueous fluids is thus crucial to understanding how water impacts Earth's geodynamics. Here we demonstrate that ductile flow exerts a dynamic control on water-rich fluid circulation in mantle shear zones. Based on amphibole distribution and using dislocation slip-systems as a proxy for syn-tectonic water content in olivine, we highlight fluid accumulation around fine-grained layers dominated by grain-size-sensitive creep. This fluid aggregation correlates with dislocation creep-accommodated strain that localizes in water-rich layers. We also give evidence of cracking induced by fluid pressure where the highest amount of water is expected. These results emphasize long-term fluid pumping attributed to creep cavitation and associated phase nucleation during grain size reduction. Considering the ubiquitous process of grain size reduction during strain localization, our findings shed light on multiple fluid reservoirs in the crust and mantle. PMID:28593947

Tracking reaction dynamics in solution by pump-probe X-ray absorption spectroscopy and X-ray liquidography (solution scattering).

PubMed

Kim, Jeongho; Kim, Kyung Hwan; Oang, Key Young; Lee, Jae Hyuk; Hong, Kiryong; Cho, Hana; Huse, Nils; Schoenlein, Robert W; Kim, Tae Kyu; Ihee, Hyotcherl

2016-03-07

Characterization of transient molecular structures formed during chemical and biological processes is essential for understanding their mechanisms and functions. Over the last decade, time-resolved X-ray liquidography (TRXL) and time-resolved X-ray absorption spectroscopy (TRXAS) have emerged as powerful techniques for molecular and electronic structural analysis of photoinduced reactions in the solution phase. Both techniques make use of a pump-probe scheme that consists of (1) an optical pump pulse to initiate a photoinduced process and (2) an X-ray probe pulse to monitor changes in the molecular structure as a function of time delay between pump and probe pulses. TRXL is sensitive to changes in the global molecular structure and therefore can be used to elucidate structural changes of reacting solute molecules as well as the collective response of solvent molecules. On the other hand, TRXAS can be used to probe changes in both local geometrical and electronic structures of specific X-ray-absorbing atoms due to the element-specific nature of core-level transitions. These techniques are complementary to each other and a combination of the two methods will enhance the capability of accurately obtaining structural changes induced by photoexcitation. Here we review the principles of TRXL and TRXAS and present recent application examples of the two methods for studying chemical and biological processes in solution. Furthermore, we briefly discuss the prospect of using X-ray free electron lasers for the two techniques, which will allow us to keep track of structural dynamics on femtosecond time scales in various solution-phase molecular reactions.

Photoisomerization and photoionization of the photoactive yellow protein chromophore in solution.

PubMed

Larsen, Delmar S; Vengris, Mikas; van Stokkum, Ivo H M; van der Horst, Michael A; de Weerd, Frank L; Hellingwerf, Klaas J; van Grondelle, Rienk

2004-04-01

Dispersed pump-dump-probe spectroscopy has the ability to characterize and identify the underlying ultrafast dynamical processes in complicated chemical and biological systems. This technique builds on traditional pump-probe techniques by exploring both ground- and excited-state dynamics and characterizing the connectivity between constituent transient states. We have used the dispersed pump-dump-probe technique to investigate the ground-state dynamics and competing excited-state processes in the excitation-induced ultrafast dynamics of thiomethyl p-coumaric acid, a model chromophore for the photoreceptor photoactive yellow protein. Our results demonstrate the parallel formation of two relaxation pathways (with multiple transient states) that jointly lead to two different types of photochemistry: cis-trans isomerization and detachment of a hydrated electron. The relative transition rates and quantum yields of both pathways have been determined. We find that the relaxation of the photoexcited chromophores involves multiple, transient ground-state intermediates and the chromophore in solution does not generate persistent photoisomerized products, but instead undergoes photoionization resulting in the generation of detached electrons and radicals. These results are of great value in interpreting the more complex dynamical changes in the optical properties of the photoactive yellow protein.

Photoisomerization and Photoionization of the Photoactive Yellow Protein Chromophore in Solution

PubMed Central

Larsen, Delmar S.; Vengris, Mikas; van Stokkum, Ivo H. M.; van der Horst, Michael A.; de Weerd, Frank L.; Hellingwerf, Klaas J.; van Grondelle, Rienk

2004-01-01

Dispersed pump-dump-probe spectroscopy has the ability to characterize and identify the underlying ultrafast dynamical processes in complicated chemical and biological systems. This technique builds on traditional pump-probe techniques by exploring both ground- and excited-state dynamics and characterizing the connectivity between constituent transient states. We have used the dispersed pump-dump-probe technique to investigate the ground-state dynamics and competing excited-state processes in the excitation-induced ultrafast dynamics of thiomethyl p-coumaric acid, a model chromophore for the photoreceptor photoactive yellow protein. Our results demonstrate the parallel formation of two relaxation pathways (with multiple transient states) that jointly lead to two different types of photochemistry: cis-trans isomerization and detachment of a hydrated electron. The relative transition rates and quantum yields of both pathways have been determined. We find that the relaxation of the photoexcited chromophores involves multiple, transient ground-state intermediates and the chromophore in solution does not generate persistent photoisomerized products, but instead undergoes photoionization resulting in the generation of detached electrons and radicals. These results are of great value in interpreting the more complex dynamical changes in the optical properties of the photoactive yellow protein. PMID:15041690

Biological research by optically pumped far infrared lasers

NASA Astrophysics Data System (ADS)

Zhengyu, Mi

1989-05-01

The FIR breeding for paddy rice, black bean and wheat, the chlorophyll mutation of paddy rice induced by optically pumped FIR laser, etc., are presented. The results of SDS electrophoresis analysis of soluble proteins of Drosophita melanrgaster irradiated by optically pumped FIR laser are described and discussed.

Piezoelectric Field Enhanced Second-Order Nonlinear Optical Susceptibilities in Wurtzite GaN/AlGaN Quantum Wells

NASA Technical Reports Server (NTRS)

Liu, Ansheng; Chuang, S.-L.; Ning, C. Z.; Woo, Alex (Technical Monitor)

1999-01-01

Second-order nonlinear optical processes including second-harmonic generation, optical rectification, and difference-frequency generation associated with intersubband transitions in wurtzite GaN/AlGaN quantum well (QW) are investigated theoretically. Taking into account the strain-induced piezoelectric (PZ) effects, we solve the electronic structure of the QW from coupled effective-mass Schrodinger equation and Poisson equation including the exchange-correlation effect under the local-density approximation. We show that the large PZ field in the QW breaks the symmetry of the confinement potential profile and leads to large second-order susceptibilities. We also show that the interband optical pump-induced electron-hole plasma results in an enhancement in the maximum value of the nonlinear coefficients and a redshift of the peak position in the nonlinear optical spectrum. By use of the difference-frequency generation, THz radiation can be generated from a GaN/Al(0.75)Ga(0.25)N with a pump laser of 1.55 micron.

Research on the liquid coolant applied in the high repetition rate slab amplifier

NASA Astrophysics Data System (ADS)

Wang, Bingyan; Li, Yangshuai; Zhang, Panzheng; Wang, Li; Zhang, Yanli; Feng, Tao; Zhou, Qiong; Liu, Qiang; Li, Haiyuan; Zhang, Xu; Zhou, Shenlei; Ma, Weixin; Zhu, Jian; Zhu, Jianqiang

2018-03-01

High repetition rate slab amplifier (HRRSA) is extraordinarily indispensable for the future fusion power plant, ultra-short laser, laser weapon, and so on. Thermal controlling is the decisive factor for the repetition rate and the output energy of the slab amplifier. For larger clear aperture HRRSA, flash-lamp pumped slab amplifier based on neodymium phosphate glass (Nd:glass) is chosen with the liquid cooling. The liquid coolant circulates across the Nd:glass and takes off the thermal induced in the pumping process. A novel liquid coolant (Series A) whose refractive index is the same with Nd:glass is proposed to alleviate the wavefront distortion induced by thermal. The chemical stability of the liquid coolant under high energy flash-lamp irradiation with 200 shots and under the irradiation of a 1053nm laser with 19 hours and 37 hours are experimented. The results show that the chemical stability of the liquid coolant is stable under irradiation.

Temperature dependence of laser induced insulator-metal transition in VO2

NASA Astrophysics Data System (ADS)

Wang, Siming; Bar-Ad, Shimshon; Ramirez, Juan Gabriel; Huppert, Dan; Schuller, Ivan K.

2013-03-01

We performed optical pump-probe experiments on VO2 thin films with low laser fluence at temperatures ranging across the insulator-metal transition (IMT). At room temperature, the reflectivity of VO2 increases in the first 400-500 fs when pumped by 150 fs laser pulses. An exponential decay of the reflectivity is observed in the following 1 ps. Interestingly, as the temperature approaches the transition temperature (340 K), the reflectivity shows a second increase on an 80 ps time scale following the exponential decay, indicating an IMT. We propose that the decay of the reflectivity is due to electron-phonon thermalization, which raises the phonon temperature and causes a superheating of the lattice. This process provides the latent heat and induces the IMT on the 80 ps time scale. The coexistence of the insulating and metallic phases is observed in the reflectivity measurements for temperatures above 340 K. This work is supported by the Air Force Office of Scientific Research No. FA9550-12-1-0381.

Magnetic-field-induced crossover from the inverse Faraday effect to the optical orientation in EuTe

NASA Astrophysics Data System (ADS)

Pavlov, V. V.; Pisarev, R. V.; Nefedov, S. G.; Akimov, I. A.; Yakovlev, D. R.; Bayer, M.; Henriques, A. B.; Rappl, P. H. O.; Abramof, E.

2018-05-01

A time-resolved optical pump-probe technique has been applied for studying the ultrafast dynamics in the magnetic semiconductor EuTe near the absorption band gap. We show that application of external magnetic field up to 6 T results in crossover from the inverse Faraday effect taking place on the femtosecond time scale to the optical orientation phenomenon with an evolution in the picosecond time domain. We propose a model which includes both these processes, possessing different spectral and temporal properties. The circularly polarized optical pumping induces the electronic transition 4 f 7 5 d 0 → 4 f 6 5 d 1 forming the absorption band gap in EuTe. The observed crossover is related to a strong magnetic-field shift of the band gap in EuTe at low temperatures. It was found that manipulation of spin states on intrinsic defect levels takes place on a time scale of 19 ps in the applied magnetic field of 6 T.

Electron gyroharmonic effects in ionization and electron acceleration during high-frequency pumping in the ionosphere.

PubMed

Gustavsson, B; Leyser, T B; Kosch, M; Rietveld, M T; Steen, A; Brändström, B U E; Aso, T

2006-11-10

Optical emissions and incoherent scatter radar data obtained during high-frequency electromagnetic pumping of the ionospheric plasma from the ground give data on electron energization in an energy range from 2 to 100 eV. Optical emissions at 4278 A from N2+ that require electrons with energies above the 18 eV ionization energy give the first images ever of pump-induced ionization of the thermosphere. The intensity at 4278 A is asymmetric around the ionospheric electron gyroharmonic, being stronger above the gyroresonance. This contrasts with emissions at 6300 A from O(1D) and of electron temperature enhancements, which have minima at the gyroharmonic but have no apparent asymmetry. This direct evidence of pump-induced ionization contradicts previous indirect evidence, which indicated that ionization is most efficiently produced when the pump frequency was below the gyroharmonic.

Experimental Waterflow Determination of the Dynamic Hydraulic Transfer Function for the J-2X Oxidizer Turbopump. Part Two; Results and Interpretation

NASA Technical Reports Server (NTRS)

Zoladz, Tom; Patel, Sandeep; Lee, Erik; Karon, Dave

2011-01-01

Experimental results describing the hydraulic dynamic pump transfer matrix (Yp) for a cavitating J-2X oxidizer turbopump inducer+impeller tested in subscale waterflow are presented. The transfer function is required for integrated vehicle pogo stability analysis as well as optimization of local inducer pumping stability. Dynamic transfer functions across widely varying pump hydrodynamic inlet conditions are extracted from measured data in conjunction with 1D-model based corrections. Derived Dynamic transfer functions are initially interpreted relative to traditional Pogo pump equations. Water-to-liquid oxygen scaling of measured cavitation characteristics are discussed. Comparison of key dynamic transfer matrix terms derived from waterflow testing are made with those implemented in preliminary Ares Upper Stage Pogo stability modeling. Alternate cavitating pump hydraulic dynamic equations are suggested which better reflect frequency dependencies of measured transfer matrices.

Quantitative assessment of haemolysis secondary to modern infusion pumps.

PubMed

Poder, T G; Boileau, J-C; Lafrenière, R; Thibault, L; Carrier, N; de Grandmont, M-J; Beauregard, P

2017-04-01

Although most studies have shown that little haemolysis is induced by infusion pumps, there are some notable exceptions. Only limited data are available on the actual infusion pumps that are most used in hospitals in Quebec and elsewhere, namely, the Infusomat ® Space (peristaltic), Plum A+™ (piston) and Colleague ® CXE (shuttle) pumps. Haemolysis and potassium levels were compared before and after the use of the three different infusion pumps. Using 135 units of packed red blood cells (RBCs) aged from 10 to 28 days, 27 measurements were taken for each pump at various flow rates (30, 60, 150, 300 and 450 ml/h) and were compared with measurements taken before using the pumps. The range of flow rates was chosen to cover those of paediatric and adult transfusions. The shuttle- and piston-type pumps resulted in low haemolysis levels. The peristaltic-type pump produced significantly more haemolysis, which worsened at low flow rates, but the absolute value of haemolysis remained within the range recommended by the regulatory agencies in North America and Europe. Approximately two-thirds of the haemolysis produced by the peristaltic-type pump seemed to be secondary to the use of an antisiphon valve (ASV) on the transfusion line recommended by the manufacturer. Potassium levels did not increase with the use of the pumps. Modern infusion pumps widely used in hospitals in Quebec and elsewhere produce non-threatening levels of haemolysis during the transfusion of packed RBCs aged from 10 to 28 days. ASVs appear to induce additional haemolysis, and we do not recommend using them for blood transfusion. © 2017 International Society of Blood Transfusion.

PUMPS FOR LIQUID CURRENT-CONDUCTING MATERIAL

DOEpatents

Watt, D.A.

1958-12-23

An induction-type liquid conductor pump is described wherein the induced current flow is substantially tnansverse to the flow of the liquid in the duct, thus eliminating parallel current flow that tends to cause unwanted pressures resulting in turbulence, eddy-flow, heating losses, and reduced pumping efficiency. This improvement is achieved by offering the parallel current a path of lower impedance along the duct than that offered by the liquid so that the induced currents remaining in the liquid flow in a substantially transverse directlon. Thick copper bars are brazed to the liquid duct parallel to the flow, and additional induced currents are created in the copper bars of appropriate magnitude to balance the ohmic drop ln the current paths outside of the liquid metal.

Low-thrust chemical propulsion system pump technology

NASA Technical Reports Server (NTRS)

Sabiers, R. L.; Siebenhaar, A.

1981-01-01

Candidate pump and driver systems for low thrust cargo orbit transfer vehicle engines which deliver large space structures to geosynchronous equatorial orbit and beyond are evaluated. The pumps operate to 68 atmospheres (1000 psi) discharge pressure and flowrates suited to cryogenic engines using either LOX/methane or LOX/hydrogen propellants in thrust ranges from 445 to 8900 N (100 to 2000 lb F). Analysis of the various pumps and drivers indicate that the low specific speed requirement will make high fluid efficiencies difficult to achieve. As such, multiple stages are required. In addition, all pumps require inducer stages. The most attractive main pumps are the multistage centrifugal pumps.

Ultra wide band supercontinuum generation in air-silica holey fibers by SHG-induced modulation instabilities.

PubMed

Tombelaine, Vincent; Lesvigne, Christelle; Leproux, Philippe; Grossard, Ludovic; Couderc, Vincent; Auguste, Jean-Louis; Blondy, Jean-Marc; Huss, Guillaume; Pioger, Paul-Henri

2005-09-19

Second harmonic generation in an air-silica microstructured optical fiber pumped by subnanosecond pulses is used in order to initiate modulation instability processes in normal and anomalous dispersion regimes. This allows us to generate an ultra wide and flat supercontinuum (350-1750 nm), covering the entire transparency window of silica and exhibiting a singlemode transverse profile in visible range.

Adiabatic Pumping Mechanism for Ion Motive ATPases

NASA Astrophysics Data System (ADS)

Astumian, R. Dean

2003-09-01

An ion motive ATPase is a membrane protein that pumps ions across the membrane at the expense of the chemical energy of adenosine triphosphate (ATP) hydrolysis. Here we describe how an external electric field, by inducing transitions between several protein configurations, can also power this pump. The underlying mechanism may be very similar to that of a recently constructed adiabatic electron pump [

Few-cycle solitons and supercontinuum generation with cascaded quadratic nonlinearities in unpoled lithium niobate ridge waveguides.

PubMed

Guo, Hairun; Zeng, Xianglong; Zhou, Binbin; Bache, Morten

2014-03-01

Formation and interaction of few-cycle solitons in a lithium niobate ridge waveguide are numerically investigated. The solitons are created through a cascaded phase-mismatched second-harmonic generation process, which induces a dominant self-defocusing Kerr-like nonlinearity on the pump pulse. The inherent material self-focusing Kerr nonlinearity is overcome over a wide wavelength range, and self-defocusing solitons are supported from 1100 to 1900 nm, covering the whole communication band. Single cycle self-compressed solitons and supercontinuum generation spanning 1.3 octaves are observed when pumped with femtosecond nanojoule pulses at 1550 nm. The waveguide is not periodically poled, as quasi-phase-matching would lead to detrimental nonlinear effects impeding few-cycle soliton formation.

Numerical simulation of a battlefield Nd:YAG laser

NASA Astrophysics Data System (ADS)

Henriksson, Markus; Sjoqvist, Lars; Uhrwing, Thomas

2005-11-01

A numeric model has been developed to identify the critical components and parameters in improving the output beam quality of a flashlamp pumped Q-switched Nd:YAG laser with a folded Porro-prism resonator and polarization output coupling. The heating of the laser material and accompanying thermo-optical effects are calculated using the finite element partial differential equations package FEMLAB allowing arbitrary geometries and time distributions. The laser gain and the cavity are modeled with the physical optics simulation code GLAD including effects such as gain profile, thermal lensing and stress-induced birefringence, the Pockels cell rise-time and component aberrations. The model is intended to optimize the pumping process of an OPO providing radiation to be used for ranging, imaging or optical countermeasures.

Effects of stratospheric ozone depletion, solar UV radiation, and climate change on biogeochemical cycling: interactions and feedbacks

DOE PAGES

Erickson III, David J.; Sulzberger, Barbara; Zepp, Richard G.; ...

2014-11-07

Climate change modulates the effects of solar UV radiation on biogeochemical cycles in terrestrial and aquatic ecosystems, particularly for carbon cycling, resulting in UV-mediated positive or negative feedbacks on climate. Possible positive feedbacks discussed in this assessment include: (i) enhanced UV-induced mineralisation of above ground litter due to aridification; (ii) enhanced UV-induced mineralisation of photoreactive dissolved organic matter (DOM) in aquatic ecosystems due to changes in continental runoff and ice melting; (iii) reduced efficiency of the biological pump due to UV-induced bleaching of coloured dissolved organic matter (CDOM) in stratified aquatic ecosystems, where CDOM protects phytoplankton from the damaging solarmore » UV-B radiation. Mineralisation of organic matter results in the production and release of CO 2, whereas the biological pump is the main biological process for CO 2 removal by aquatic ecosystems. This research also assesses the interactive effects of solar UV radiation and climate change on the biogeochemical cycling of aerosols and trace gases other than CO 2, as well as of chemical and biological contaminants. Lastly,, interacting effects of solar UV radiation and climate change on biogeochemical cycles are particularly pronounced at terrestrial-aquatic interfaces.« less

Dissipative preparation of steady Greenberger-Horne-Zeilinger states for Rydberg atoms with quantum Zeno dynamics

NASA Astrophysics Data System (ADS)

Shao, X. Q.; Wu, J. H.; Yi, X. X.; Long, Gui-Lu

2017-12-01

Inspired by a recent work [F. Reiter, D. Reeb, and A. S. Sørensen, Phys. Rev. Lett. 117, 040501 (2016), 10.1103/PhysRevLett.117.040501], we present a simplified proposal for dissipatively preparing a Greenberger-Horne-Zeilinger (GHZ) state of three Rydberg atoms in a cavity. The Z pumping is implemented under the action of the spontaneous emission of Λ -type atoms and the quantum Zeno dynamics induced by strong continuous coupling. In the meantime, a dissipative Rydberg pumping breaks up the stability of the state | GHZ+〉 in the process of Z pumping, making | GHZ-〉 the unique steady state of the system. Compared with the former scheme, the number of driving fields acting on atoms is greatly reduced and only a single-mode cavity is required. The numerical simulation of the full master equation reveals that a high fidelity ˜98 % can be obtained with the currently achievable parameters in the Rydberg-atom-cavity system.

Near-Infrared Laser Pumped Intersubband THz Laser Gain in InGaAs-AlAsSb-InP Quantum Wells

NASA Technical Reports Server (NTRS)

Liu, An-Sheng; Ning, Cun-Zheng

1999-01-01

We investigate the possibility of using InGaAs-AlAsSb-InP coupled quantum wells to generate THz radiation by means of intersubband optical pumping. We show that large conduction band offsets of these quantum wells make it possible to use conventional near-infrared diode lasers around 1.55 micron as pump sources. Taking into account the pump-probe coherent interaction and the optical nonlinearity for the pump field, we calculate the THz gain of the quantum well structure. We show that resonant Raman scattering enhances the THz gain at low and moderate optical pumping levels. When the pump intensity is strong, the THz gain is reduced by pump-induced population redistribution and pump-probe coherent interactions.

Persistent wind-induced enhancement of diffusive CO2 transport in a mountain forest snowpack

Treesearch

D. R. Bowling; W. J. Massman

2011-01-01

Diffusion dominates the transport of trace gases between soil and the atmosphere. Pressure gradients induced by atmospheric flow and wind interacting with topographical features cause a small but persistent bulk flow of air within soil or snow. This forcing, called pressure pumping or wind pumping, leads to a poorly quantified enhancement of gas transport beyond the...

High V-PPase activity is beneficial under high salt loads, but detrimental without salinity.

PubMed

Graus, Dorothea; Konrad, Kai R; Bemm, Felix; Patir Nebioglu, Meliha Görkem; Lorey, Christian; Duscha, Kerstin; Güthoff, Tilman; Herrmann, Johannes; Ferjani, Ali; Cuin, Tracey Ann; Roelfsema, M Rob G; Schumacher, Karin; Neuhaus, H Ekkehard; Marten, Irene; Hedrich, Rainer

2018-06-25

The membrane-bound proton-pumping pyrophosphatase (V-PPase), together with the V-type H + -ATPase, generates the proton motive force that drives vacuolar membrane solute transport. Transgenic plants constitutively overexpressing V-PPases were shown to have improved salinity tolerance, but the relative impact of increasing PP i hydrolysis and proton-pumping functions has yet to be dissected. For a better understanding of the molecular processes underlying V-PPase-dependent salt tolerance, we transiently overexpressed the pyrophosphate-driven proton pump (NbVHP) in Nicotiana benthamiana leaves and studied its functional properties in relation to salt treatment by primarily using patch-clamp, impalement electrodes and pH imaging. NbVHP overexpression led to higher vacuolar proton currents and vacuolar acidification. After 3 d in salt-untreated conditions, V-PPase-overexpressing leaves showed a drop in photosynthetic capacity, plasma membrane depolarization and eventual leaf necrosis. Salt, however, rescued NbVHP-hyperactive cells from cell death. Furthermore, a salt-induced rise in V-PPase but not of V-ATPase pump currents was detected in nontransformed plants. The results indicate that under normal growth conditions, plants need to regulate the V-PPase pump activity to avoid hyperactivity and its negative feedback on cell viability. Nonetheless, V-PPase proton pump function becomes increasingly important under salt stress for generating the pH gradient necessary for vacuolar proton-coupled Na + sequestration. © 2018 The Authors. New Phytologist © 2018 New Phytologist Trust.

Effect of leading edge sweep on the performance of cavitating inducer of LOX booster turbopump used in semicryogenic engine

NASA Astrophysics Data System (ADS)

Mishra, Arpit; Ghosh, Parthasarathi

2017-02-01

As a part of the developmental effort towards the realization of a staged combustion cycle based liquid rocket engine, a program on simulation of the LOX booster pump for performance characterization has been taken up. Earlier reported work shows that the pump inducer works satisfactorily under cavitating conditions for the throttling range varying from 90% to 113%. However stall occurs below 90% of the designed flow rate which is to be strongly associated with the inlet backflow vortices due to flow separation [1]. It is envisaged that leading edge sweep may help in to controls the incipience and growth of the backflow vortices at the inlet leading edge tip of axial flow inducer leading to a wider operating range. In this paper, steady state 3D CFD analysis of rotating inducer is performed to examine the effect of leading edge sweep on the performance of axial flow LOX pump inducer using ANSYS® CFX and has been compared with the performance of the inducer reported by Mishra and Ghosh [1].

Phase dynamics of oscillating magnetizations coupled via spin pumping

NASA Astrophysics Data System (ADS)

Taniguchi, Tomohiro

2018-05-01

A theoretical formalism is developed to simultaneously solve equation of motion of the magnetizations in two ferromagnets and the spin-pumping induced spin transport equation. Based on the formalism, a coupled motion of the magnetizations in a self-oscillation state is studied. The spin pumping is found to induce an in-phase synchronization of the magnetizations for the oscillation around the easy axis. For an out-of-plane self-oscillation around the hard axis, on the other hand, the spin pumping leads to an in-phase synchronization in a small current region, whereas an antiphase synchronization is excited in a large current region. An analytical theory based on the phase equation reveals that the phase difference between the magnetizations in a steady state depends on the oscillation direction, clockwise or counterclockwise, of the magnetizations.

Femtosecond measurements of near-infrared pulse induced mid-infrared transmission modulation of quantum cascade lasers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cai, Hong; Liu, Sheng; Center for Advanced Studied in Photonics Research

2014-05-26

We temporally resolved the ultrafast mid-infrared transmission modulation of quantum cascade lasers (QCLs) using a near-infrared pump/mid-infrared probe technique at room temperature. Two different femtosecond wavelength pumps were used with photon energy above and below the quantum well (QW) bandgap. The shorter wavelength pump modulates the mid-infrared probe transmission through interband transition assisted mechanisms, resulting in a high transmission modulation depth and several nanoseconds recovery lifetime. In contrast, pumping with a photon energy below the QW bandgap induces a smaller transmission modulation depth but much faster (several picoseconds) recovery lifetime, attributed to intersubband transition assisted mechanisms. The latter ultrafast modulationmore » (>60 GHz) could provide a potential way to realize fast QCL based free space optical communication.« less

Manufacturing with the Sun

NASA Astrophysics Data System (ADS)

Murphy, L. M.; Hauser, S. G.; Clyne, R. J.

1992-05-01

Concentrated solar radiation is now a viable alternative energy source for many advanced manufacturing processes. Researchers at the National Renewable Energy Laboratory (NREL) have demonstrated the feasibility of processes such as solar-induced surface transformation of materials (SISTM), solar-based manufacturing, and solar-pumped lasers. Researchers are also using sunlight to decontaminate water and soils polluted with organic compounds; these techniques could provide manufacturers with innovative alternatives to traditional methods of waste management. The solar technology that is now being integrated into today's manufacturing processes offers even greater potential for tomorrow, especially as applied to the radiation-abundant environment available in space and on the lunar surface.

Manufacturing with the Sun

NASA Astrophysics Data System (ADS)

Murphy, Lawrence M.; Hauser, Steven G.; Clyne, Richard J.

1991-12-01

Concentrated solar radiation is now a viable alternative source for many advanced manufacturing processes. Researchers at the National Renewable Energy Laboratory (NREL) have demonstrated the feasibility of processes such as solar induced surface transformation of materials (SISTM), solar based manufacturing, and solar pumped lasers. Researchers are also using sunlight to decontaminate water and soils polluted with organic compounds; these techniques could provide manufacturers with innovative alternatives to traditional methods of waste management. The solar technology that is now being integrated into today's manufacturing processes offer greater potential for tomorrow, especially as applied to the radiation abundant environment available in space and on the lunar surface.

Manufacturing with the Sun

NASA Technical Reports Server (NTRS)

Murphy, Lawrence M.; Hauser, Steven G.; Clyne, Richard J.

1991-01-01

Concentrated solar radiation is now a viable alternative source for many advanced manufacturing processes. Researchers at the National Renewable Energy Laboratory (NREL) have demonstrated the feasibility of processes such as solar induced surface transformation of materials (SISTM), solar based manufacturing, and solar pumped lasers. Researchers are also using sunlight to decontaminate water and soils polluted with organic compounds; these techniques could provide manufacturers with innovative alternatives to traditional methods of waste management. The solar technology that is now being integrated into today's manufacturing processes offer greater potential for tomorrow, especially as applied to the radiation abundant environment available in space and on the lunar surface.

Simulation of groundwater and surface-water interaction and effects of pumping in a complex glacial-sediment aquifer, east central Massachusetts

USGS Publications Warehouse

Eggleston, Jack R.; Carlson, Carl S.; Fairchild, Gillian M.; Zarriello, Phillip J.

2012-01-01

The effects of groundwater pumping on surface-water features were evaluated by use of a numerical groundwater model developed for a complex glacial-sediment aquifer in northeastern Framingham, Massachusetts, and parts of surrounding towns. The aquifer is composed of sand, gravel, silt, and clay glacial-fill sediments up to 270 feet thick over an irregular fractured bedrock surface. Surface-water bodies, including Cochituate Brook, the Sudbury River, Lake Cochituate, Dudley Pond, and adjoining wetlands, are in hydraulic connection with the aquifer and can be affected by groundwater withdrawals. Groundwater and surface-water interaction was simulated with MODFLOW-NWT under current conditions and a variety of hypothetical pumping conditions. Simulations of hypothetical pumping at reactivated water supply wells indicate that captured groundwater would decrease baseflow to the Sudbury River and induce recharge from Lake Cochituate. Under constant (steady-state) pumping, induced groundwater recharge from Lake Cochituate was equal to about 32 percent of the simulated pumping rate, and flow downstream in the Sudbury River decreased at the same rate as pumping. However, surface water responded quickly to pumping stresses. When pumping was simulated for 1 month and then stopped, streamflow depletions decreased by about 80 percent within 2 months and by about 90 percent within about 4 months. The fast surface water response to groundwater pumping offers the potential to substantially reduce streamflow depletions during periods of low flow, which are of greatest concern to the ecological integrity of the river. Results indicate that streamflow depletion during September, typically the month of lowest flow, can be reduced by 29 percent by lowering the maximum pumping rates to near zero during September. Lowering pumping rates for 3 months (July through September) reduces streamflow depletion during September by 79 percent as compared to constant pumping. These results demonstrate that a seasonal or streamflow-based groundwater pumping schedule can reduce the effects of pumping during periods of low flow.

Interplay between three RND efflux pumps in doxycycline-selected strains of Burkholderia thailandensis.

PubMed

Biot, Fabrice Vincent; Lopez, Mélanie Monique; Poyot, Thomas; Neulat-Ripoll, Fabienne; Lignon, Sabrina; Caclard, Arnaud; Thibault, François Michel; Peinnequin, Andre; Pagès, Jean-Marie; Valade, Eric

2013-01-01

Efflux systems are involved in multidrug resistance in most Gram-negative non-fermentative bacteria. We have chosen Burkholderia thailandensis to dissect the development of multidrug resistance phenotypes under antibiotic pressure. We used doxycycline selection to obtain several resistant B. thailandensis variants. The minimal inhibitory concentrations of a large panel of structurally unrelated antibiotics were determined ± the efflux pump inhibitor phenylalanine-arginine ß-naphthylamide (PAßN). Membrane proteins were identified by proteomic method and the expressions of major efflux pumps in the doxycycline selected variants were compared to those of the parental strains by a quantitative RT-PCR analysis. Doxycycline selected variants showed a multidrug resistance in two major levels corresponding to the overproduction of two efflux pumps depending on its concentration: AmrAB-OprA and BpeEF-OprC. The study of two mutants, each lacking one of these pumps, indicated that a third pump, BpeAB-OprB, could substitute for the defective pump. Surprisingly, we observed antagonistic effects between PAßN and aminoglycosides or some ß-lactams. PAßN induced the overexpression of AmrAB-OprA and BpeAB-OprB pump genes, generating this unexpected effect. These results may account for the weak activity of PAßN in some Gram-negative species. We clearly demonstrated two antagonistic effects of this molecule on bacterial cells: the blocking of antibiotic efflux and an increase in efflux pump gene expression. Thus, doxycycline is a very efficient RND efflux pump inducer and PAßN may promote the production of some efflux pumps. These results should be taken into account when considering antibiotic treatments and in future studies on efflux pump inhibitors.

The energetics of the primary proton transfer in bacteriorhodopsin revisited: it is a sequential light-induced charge separation after all.

PubMed

Braun-Sand, Sonja; Sharma, Pankaz K; Chu, Zhen T; Pisliakov, Andrei V; Warshel, Arieh

2008-05-01

The light-induced proton transport in bacteriorhodopsin has been considered as a model for other light-induced proton pumps. However, the exact nature of this process is still unclear. For example, it is not entirely clear what the driving force of the initial proton transfer is and, in particular, whether it reflects electrostatic forces or other effects. The present work simulates the primary proton transfer (PT) by a specialized combination of the EVB and the QCFF/PI methods. This combination allows us to obtain sufficient sampling and a quantitative free energy profile for the PT at different protein configurations. The calculated profiles provide new insight about energetics of the primary PT and its coupling to the protein conformational changes. Our finding confirms the tentative analysis of an earlier work (A. Warshel, Conversion of light energy to electrostatic energy in the proton pump of Halobacterium halobium, Photochem. Photobiol. 30 (1979) 285-290) and determines that the overall PT process is driven by the energetics of the charge separation between the Schiff base and its counterion Asp85. Apparently, the light-induced relaxation of the steric energy of the chromophore leads to an increase in the ion-pair distance, and this drives the PT process. Our use of the linear response approximation allows us to estimate the change in the protein conformational energy and provides the first computational description of the coupling between the protein structural changes and the PT process. It is also found that the PT is not driven by twist-modulated changes of the Schiff base's pKa, changes in the hydrogen bond directionality, or other non-electrostatic effects. Overall, based on a consistent use of structural information as the starting point for converging free energy calculations, we conclude that the primary event should be described as a light-induced formation of an unstable ground state, whose relaxation leads to charge separation and to the destabilization of the ion-pair state. This provides the driving force for the subsequent PT steps.

Cross-phase modulation spectral shifting: nonlinear phase contrast in a pump-probe microscope

PubMed Central

Wilson, Jesse W.; Samineni, Prathyush; Warren, Warren S.; Fischer, Martin C.

2012-01-01

Microscopy with nonlinear phase contrast is achieved by a simple modification to a nonlinear pump-probe microscope. The technique measures cross-phase modulation by detecting a pump-induced spectral shift in the probe pulse. Images with nonlinear phase contrast are acquired both in transparent and absorptive media. In paraffin-embedded biopsy sections, cross-phase modulation complements the chemically-specific pump-probe images with structural context. PMID:22567580

Pressure measurement in supersonic air flow by differential absorptive laser-induced thermal acoustics.

PubMed

Hart, Roger C; Herring, G C; Balla, R Jeffrey

2007-06-15

Nonintrusive, off-body flow barometry in Mach 2 airflow has been demonstrated in a large-scale supersonic wind tunnel using seedless laser-induced thermal acoustics (LITA). The static pressure of the gas flow is determined with a novel differential absorption measurement of the ultrasonic sound produced by the LITA pump process. Simultaneously, the streamwise velocity and static gas temperature of the same spatially resolved sample volume were measured with this nonresonant time-averaged LITA technique. Mach number, temperature, and pressure have 0.2%, 0.4%, and 4% rms agreement, respectively, in comparison with known free-stream conditions.

Pressure Measurement in Supersonic Air Flow by Differential Absorptive Laser-Induced Thermal Acoustics

NASA Technical Reports Server (NTRS)

Hart, Roger C.; Herring, Gregory C.; Balla, Robert J.

2007-01-01

Nonintrusive, off-body flow barometry in Mach-2 airflow has been demonstrated in a large-scale supersonic wind tunnel using seedless laser-induced thermal acoustics (LITA). The static pressure of the gas flow is determined with a novel differential absorption measurement of the ultrasonic sound produced by the LITA pump process. Simultaneously, stream-wise velocity and static gas temperature of the same spatially-resolved sample volume were measured with this nonresonant time-averaged LITA technique. Mach number, temperature and pressure have 0.2%, 0.4%, and 4% rms agreement, respectively, in comparison with known free-stream conditions.

Characterization of photo-induced valence tautomerism in a cobalt-dioxolene complex by ultrafast spectroscopy

NASA Astrophysics Data System (ADS)

Beni, A.; Bogani, L.; Bussotti, L.; Dei, A.; Gentili, P. L.; Righini, R.

2005-01-01

The valence tautomerism of low-spin CoIII(Cat-N-BQ)(Cat-N-SQ) was investigated by means of UV-vis pump-probe transient absorption spectroscopy in chloroform. By exciting the CT transition of the complex at 480 nm, an intramolecular electron transfer process is selectively triggered. The photo-induced charge transfer is pursued by a cascade of two main molecular events characterized by the ultrafast transient absorption spectroscopy: the first gives rise to the metastable high-spin CoII(Cat-N-BQ)2 that, secondly, reaches the chemical equilibrium with the reactant species.

Insights in nutrient sources and transport from high-frequency monitoring at the outlet pumping station of an agricultural lowland polder catchment

NASA Astrophysics Data System (ADS)

Rozemeijer, J.; Van der Grift, B.; Broers, H. P.; Berendrecht, W.; Oste, L.; Griffioen, J.

2015-12-01

In this study, we present new insights in nutrient sources and transport processes in an agricultural-dominated lowland water system based on high-frequency monitoring technology. Starting in October 2014, we have collected semi-continuous measurements of the TP and NO3 concentrations, conductivity and water temperature at a large scale pumping station at the outlet of a 576 km2 polder catchment. The semi-continuous measurements complement a water quality monitoring program at six locations within the drainage area based on conventional monthly or biweekly grab sampling. The NO3 and TP concentrations at the pumping station varied between 0.5 and 10 mgN/L and 0.1 and 0.5 mgP/L. The seasonal trends and short scale concentration dynamics clearly indicated that most of the NO3 loads at the pumping station originated from subsurface drain tubes that were active after intensive rainfall events during the winter months. A transfer function-noise model of hourly NO3 concentrations reveals that a large part of the dynamics in NO3 concentrations during the winter months can be predicted using rainfall data. In February however, NO3 concentrations were higher than predicted due to direct losses after the first manure application. The TP concentration almost doubled during operation of the pumping station. This highlights resuspension of particulate P from channel bed sediments induced by the higher flow velocities during pumping. Rainfall events that caused peaks in NO3 concentrations did not result in TP concentration peaks. Direct effects of run-off, with an association increase in the TP concentration and decrease of the NO3concentration, was only observed during rainfall event at the end of a freeze-thaw cycle. The high-frequency monitoring at the outlet of an agricultural-dominated lowland water system in combination with low-frequency monitoring within the area provided insight in nutrient sources and transport processes that are highly relevant for water quality management.

Water Flow Performance of a Superscale Model of the Fastrac Liquid Oxygen Pump

NASA Technical Reports Server (NTRS)

Skelley, Stephen; Zoladz, Thomas

2001-01-01

As part of the National Aeronautics and Space Administration's ongoing effort to lower the cost of access to space, the Marshall Space Flight Center has developed a rocket engine with 60,000 pounds of thrust for use on the Reusable Launch Vehicle technology demonstrator slated for launch in 2000. This gas generator cycle engine, known as the Fastrac engine, uses liquid oxygen and RP-1 for propellants and includes single stage liquid oxygen and RP-1 pumps and a single stage supersonic turbine on a common shaft. The turbopump design effort included the first use and application of new suction capability prediction codes and three-dimensional blade generation codes in an attempt to reduce the turbomachinery design and certification costs typically associated with rocket engine development. To verify the pump's predicted cavitation performance, a water flow test of a superscale model of the Fastrac liquid oxygen pump was conducted to experimentally evaluate the liquid oxygen pump's performance at and around the design point. The water flow test article replicated the flow path of the Fastrac liquid oxygen pump in a 1.582x scale model, including scaled seal clearances for correct leakage flow at a model operating speed of 5000 revolutions per minute. Flow entered the 3-blade axial-flow inducer, transitioned to a shrouded, 6- blade radial impeller, and discharged into a vaneless radial diffuser and collection volute. The test article included approximately 50 total and static pressure measurement locations as well as flush-mounted, high frequency pressure transducers for complete mapping of the pressure environment. The primary objectives of the water flow test were to measure the steady-state and dynamic pressure environment of the liquid oxygen pump versus flow coefficient, suction specific speed, and back face leakage flow rate. Initial results showed acceptable correlation between the predicted and experimentally measured pump head rise at low suction specific speeds. Likewise, only small circumferential variations in steady-state were observed from 80% to 120% of the design flow coefficient, matching the computational predictions and confirming that the integrated design approach has minimized any exit volute-induced distortions. The test article exhibited suction performance trends typically observed in inducer designs with virtually constant head rise with decreasing inlet pressure until complete pump head breakdown. Unfortunately, the net positive suction head at 3% head fall-off occurred far below that predicted at all tested flow coefficients, resulting in a negative net positive suction head margin at the design point in water. Additional testing to map the unsteady pressure environment was conducted and cavitation-induced flow disturbances at the inducer inlet were observed. Two distinct disturbances were identified, one rotating and one stationary relative to the fixed frame of reference, while the transition from one regime to the next produced significant effects on the steady state pump performance. The impact of the unsteady phenomena and the corresponding energy losses on the unexpectedly poor pump performance is also discussed.

Pumped shot noise in adiabatically modulated graphene-based double-barrier structures.

PubMed

Zhu, Rui; Lai, Maoli

2011-11-16

Quantum pumping processes are accompanied by considerable quantum noise. Based on the scattering approach, we investigated the pumped shot noise properties in adiabatically modulated graphene-based double-barrier structures. It is found that compared with the Poisson processes, the pumped shot noise is dramatically enhanced where the dc pumped current changes flow direction, which demonstrates the effect of the Klein paradox.

Pumped shot noise in adiabatically modulated graphene-based double-barrier structures

NASA Astrophysics Data System (ADS)

Zhu, Rui; Lai, Maoli

2011-11-01

Quantum pumping processes are accompanied by considerable quantum noise. Based on the scattering approach, we investigated the pumped shot noise properties in adiabatically modulated graphene-based double-barrier structures. It is found that compared with the Poisson processes, the pumped shot noise is dramatically enhanced where the dc pumped current changes flow direction, which demonstrates the effect of the Klein paradox.

Influence of wind-induced air pressure fluctuations on topsoil gas concentrations within a Scots pine forest

NASA Astrophysics Data System (ADS)

Mohr, Manuel; Laemmel, Thomas; Maier, Martin; Schindler, Dirk

2017-04-01

Commonly it is assumed that soil gas transport is dominated by molecular diffusion. Few recent studies indicate that the atmosphere above the soil triggers non-diffusive gas transport processes in the soil, which can enhance soil gas transport and therefore soil gas efflux significantly. During high wind speed conditions, the so called pressure pumping effect has been observed: the enhancement of soil gas transport through dynamic changes in the air pressure field above the soil. However, the amplitudes and frequencies of the air pressure fluctuations responsible for pressure pumping are still uncertain. Moreover, an in situ observation of the pressure pumping effect is still missing. To investigate the pressure pumping effect, airflow measurements above and below the canopy of a Scots pine forest and high-precision relative air pressure measurements were conducted in the below-canopy space and in the soil over a measurement period of 16 weeks. To monitor the soil gas transport, a newly developed gas measurement system was used. The gas measurement system continuously injects helium as a tracer gas into the soil until a diffusive steady state is reached. With the steady state concentration profile of the tracer gas, it is possible to inversely model the gas diffusion coefficient profile of the soil. If the gas diffusion coefficient profile differed from steady state, we deduced that the soil gas transport is not only diffusive, but also influenced by non-diffusive processes. Results show that the occurrence of small air pressure fluctuations is strongly dependent on the mean above-canopy wind speed. The wind-induced air pressure fluctuations have mean amplitudes up to 10 Pa and lie in the frequency range 0.01-0.1 Hz. To describe the pumping motion of the air pressure field, the pressure pumping coefficient (PPC) was defined as the mean change in pressure per second. The PPC shows a clear quadratic dependence on mean above-canopy wind speed. Empirical modelling of the measured topsoil helium concentration demonstrated that the PPC is the most important predictor for changes in the topsoil helium concentration. Comparison of time periods with high PPC and periods of low PPC showed that the soil gas diffusion coefficient in depths between 5-10 cm increased up to 30% during periods of high PPC compared to steady state. Thus, the air pressure fluctuations observed in the atmosphere and described by the PPC penetrate into the soil and influence the topsoil gas transport.

Glutathionylation-Dependence of Na+-K+-Pump Currents Can Mimic Reduced Subsarcolemmal Na+ Diffusion

PubMed Central

Garcia, Alvaro; Liu, Chia-Chi; Cornelius, Flemming; Clarke, Ronald J.; Rasmussen, Helge H.

2016-01-01

The existence of a subsarcolemmal space with restricted diffusion for Na+ in cardiac myocytes has been inferred from a transient peak electrogenic Na+-K+ pump current beyond steady state on reexposure of myocytes to K+ after a period of exposure to K+-free extracellular solution. The transient peak current is attributed to enhanced electrogenic pumping of Na+ that accumulated in the diffusion-restricted space during pump inhibition in K+-free extracellular solution. However, there are no known physical barriers that account for such restricted Na+ diffusion, and we examined if changes of activity of the Na+-K+ pump itself cause the transient peak current. Reexposure to K+ reproduced a transient current beyond steady state in voltage-clamped ventricular myocytes as reported by others. Persistence of it when the Na+ concentration in patch pipette solutions perfusing the intracellular compartment was high and elimination of it with K+-free pipette solution could not be reconciled with restricted subsarcolemmal Na+ diffusion. The pattern of the transient current early after pump activation was dependent on transmembrane Na+- and K+ concentration gradients suggesting the currents were related to the conformational poise imposed on the pump. We examined if the currents might be accounted for by changes in glutathionylation of the β1 Na+-K+ pump subunit, a reversible oxidative modification that inhibits the pump. Susceptibility of the β1 subunit to glutathionylation depends on the conformational poise of the Na+-K+ pump, and glutathionylation with the pump stabilized in conformations equivalent to those expected to be imposed on voltage-clamped myocytes supported this hypothesis. So did elimination of the transient K+-induced peak Na+-K+ pump current when we included glutaredoxin 1 in patch pipette solutions to reverse glutathionylation. We conclude that transient K+-induced peak Na+-K+ pump current reflects the effect of conformation-dependent β1 pump subunit glutathionylation, not restricted subsarcolemmal diffusion of Na+. PMID:26958887

Glutathionylation-Dependence of Na(+)-K(+)-Pump Currents Can Mimic Reduced Subsarcolemmal Na(+) Diffusion.

PubMed

Garcia, Alvaro; Liu, Chia-Chi; Cornelius, Flemming; Clarke, Ronald J; Rasmussen, Helge H

2016-03-08

The existence of a subsarcolemmal space with restricted diffusion for Na(+) in cardiac myocytes has been inferred from a transient peak electrogenic Na(+)-K(+) pump current beyond steady state on reexposure of myocytes to K(+) after a period of exposure to K(+)-free extracellular solution. The transient peak current is attributed to enhanced electrogenic pumping of Na(+) that accumulated in the diffusion-restricted space during pump inhibition in K(+)-free extracellular solution. However, there are no known physical barriers that account for such restricted Na(+) diffusion, and we examined if changes of activity of the Na(+)-K(+) pump itself cause the transient peak current. Reexposure to K(+) reproduced a transient current beyond steady state in voltage-clamped ventricular myocytes as reported by others. Persistence of it when the Na(+) concentration in patch pipette solutions perfusing the intracellular compartment was high and elimination of it with K(+)-free pipette solution could not be reconciled with restricted subsarcolemmal Na(+) diffusion. The pattern of the transient current early after pump activation was dependent on transmembrane Na(+)- and K(+) concentration gradients suggesting the currents were related to the conformational poise imposed on the pump. We examined if the currents might be accounted for by changes in glutathionylation of the β1 Na(+)-K(+) pump subunit, a reversible oxidative modification that inhibits the pump. Susceptibility of the β1 subunit to glutathionylation depends on the conformational poise of the Na(+)-K(+) pump, and glutathionylation with the pump stabilized in conformations equivalent to those expected to be imposed on voltage-clamped myocytes supported this hypothesis. So did elimination of the transient K(+)-induced peak Na(+)-K(+) pump current when we included glutaredoxin 1 in patch pipette solutions to reverse glutathionylation. We conclude that transient K(+)-induced peak Na(+)-K(+) pump current reflects the effect of conformation-dependent β1 pump subunit glutathionylation, not restricted subsarcolemmal diffusion of Na(+). Copyright © 2016 Biophysical Society. Published by Elsevier Inc. All rights reserved.

A model investigation of turbulence-driven pressure-pumping effects on the rate of diffusion of CO2, N2O, and CH4 through layered snowpacks

Treesearch

W. J. Massman; R. A. Sommerfeld; A. R. Mosier; K. F. Zeller; T.J . Hehn; S. G. Rochelle

1997-01-01

Pressure pumping at the Earth's surface is caused by short-period atmospheric turbulence, longer-period barometric changes, and quasi-static pressure fields induced by wind blowing across irregular topography. These naturally occurring atmospheric pressure variations induce periodic fluctuations in airflow through snowpacks, soils, and any other porous media at...

Pump-probe STM light emission spectroscopy for detection of photo-induced semiconductor-metal phase transition of VO2

NASA Astrophysics Data System (ADS)

Sakai, Joe; Katano, Satoshi; Kuwahara, Masashi; Uehara, Yoichi

2017-10-01

We attempted to observe pump-probe scanning tunneling microscopy (STM)-light emission (LE) from a VO2 thin film grown on a rutile TiO2(0 0 1) substrate, with an Ag tip fixed over a semiconducting domain. Laser pulses from a Ti:sapphire laser (wavelength 920 nm pulse width less than 1.5 ps) irradiated the tip-sample gap as pump and probe light sources. With a photon energy of 2.7 eV, suggesting phase transition from semiconducting monoclinic (M) to metallic rutile (R) phases in relation to the electronic band structure, faint LE was observed roughly 30 ps after the irradiation of the pump pulse, followed by retention for roughly 20 ps. The incident energy fluence of the pump pulse at the gap was five orders of magnitude lower than the threshold value for reported photo-induced M-R phase transition. The mechanism that makes it possible to reduce the threshold fluence is discussed.

Pump-probe STM light emission spectroscopy for detection of photo-induced semiconductor-metal phase transition of VO2.

PubMed

Sakai, Joe; Katano, Satoshi; Kuwahara, Masashi; Uehara, Yoichi

2017-10-11

We attempted to observe pump-probe scanning tunneling microscopy (STM)-light emission (LE) from a VO 2 thin film grown on a rutile TiO 2 (0 0 1) substrate, with an Ag tip fixed over a semiconducting domain. Laser pulses from a Ti:sapphire laser (wavelength 920 nm; pulse width less than 1.5 ps) irradiated the tip-sample gap as pump and probe light sources. With a photon energy of 2.7 eV, suggesting phase transition from semiconducting monoclinic (M) to metallic rutile (R) phases in relation to the electronic band structure, faint LE was observed roughly 30 ps after the irradiation of the pump pulse, followed by retention for roughly 20 ps. The incident energy fluence of the pump pulse at the gap was five orders of magnitude lower than the threshold value for reported photo-induced M-R phase transition. The mechanism that makes it possible to reduce the threshold fluence is discussed.

Pump-probe imaging of laser-induced periodic surface structures after ultrafast irradiation of Si

DOE Office of Scientific and Technical Information (OSTI.GOV)

Murphy, Ryan D.; Torralva, Ben; Adams, David P.

2013-09-30

Ultrafast pump-probe microscopy has been used to investigate laser-induced periodic surface structure (LIPSS) formation on polished Si surfaces. A crater forms on the surface after irradiation by a 150 fs laser pulse, and a second, subsequent pulse forms LIPSS within the crater. Sequentially delayed images show that LIPSS with a periodicity slightly less than the fundamental laser wavelength of 780 nm appear on Si surfaces ∼50 ps after arrival of the second pump laser pulse, well after the onset of melting. LIPSS are observed on the same timescale as material removal, suggesting that their formation involves material ejection.

11. PUMP HOUSE AND WEIGHING ROOM Fish were pumped from ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

11. PUMP HOUSE AND WEIGHING ROOM Fish were pumped from floating hoppers, to the pump house (on the far right). From there they were either lifted by conveyor belt to the weighing room (top center) and thence to the holding tanks, or were washed through sealers, weighed and then sluiced to holding tanks. The process used depended upon the type and size of fish. The square cement vat (center) was to be a settling tank from which fish oil, reclaimed from the reduction process, was to be pumped into the round metal tank (above the vat). This process however, was never fully utilized before the sardines ran out. - Hovden Cannery, 886 Cannery Row, Monterey, Monterey County, CA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Restivo, M.

SRNL Environmental and Chemical Process Technology (E&CPT) was requested to perform testing of vacuum pumps per a verbal request from the Customer, SRNL Hydrogen Processing Technology. Tritium Operations is currently having difficulties procuring the Normetex™® Model 15 m 3/hr (9 CFM) vacuum pump (formerly Normetex Pompes, now Eumeca SARL). One possible solution proposed by Hydrogen Processing Technology personnel is to use two Senior Aerospace Metal Bellows MB-601 vacuum pumps piped with the heads in series, and the pumps in series (Figure 1 below). This memorandum documents the ultimate vacuum testing that was performed to determine if this concept was amore » viable alternate vacuum pump strategy. This testing dovetails with previous pump evaluations documented in references 1 and 2.« less

Hetero-site-specific X-ray pump-probe spectroscopy for femtosecond intramolecular dynamics

PubMed Central

Picón, A.; Lehmann, C. S.; Bostedt, C.; Rudenko, A.; Marinelli, A.; Osipov, T.; Rolles, D.; Berrah, N.; Bomme, C.; Bucher, M.; Doumy, G.; Erk, B.; Ferguson, K. R.; Gorkhover, T.; Ho, P. J.; Kanter, E. P.; Krässig, B.; Krzywinski, J.; Lutman, A. A.; March, A. M.; Moonshiram, D.; Ray, D.; Young, L.; Pratt, S. T.; Southworth, S. H.

2016-01-01

New capabilities at X-ray free-electron laser facilities allow the generation of two-colour femtosecond X-ray pulses, opening the possibility of performing ultrafast studies of X-ray-induced phenomena. Particularly, the experimental realization of hetero-site-specific X-ray-pump/X-ray-probe spectroscopy is of special interest, in which an X-ray pump pulse is absorbed at one site within a molecule and an X-ray probe pulse follows the X-ray-induced dynamics at another site within the same molecule. Here we show experimental evidence of a hetero-site pump-probe signal. By using two-colour 10-fs X-ray pulses, we are able to observe the femtosecond time dependence for the formation of F ions during the fragmentation of XeF2 molecules following X-ray absorption at the Xe site. PMID:27212390

Hetero-site-specific X-ray pump-probe spectroscopy for femtosecond intramolecular dynamics.

PubMed

Picón, A; Lehmann, C S; Bostedt, C; Rudenko, A; Marinelli, A; Osipov, T; Rolles, D; Berrah, N; Bomme, C; Bucher, M; Doumy, G; Erk, B; Ferguson, K R; Gorkhover, T; Ho, P J; Kanter, E P; Krässig, B; Krzywinski, J; Lutman, A A; March, A M; Moonshiram, D; Ray, D; Young, L; Pratt, S T; Southworth, S H

2016-05-23

New capabilities at X-ray free-electron laser facilities allow the generation of two-colour femtosecond X-ray pulses, opening the possibility of performing ultrafast studies of X-ray-induced phenomena. Particularly, the experimental realization of hetero-site-specific X-ray-pump/X-ray-probe spectroscopy is of special interest, in which an X-ray pump pulse is absorbed at one site within a molecule and an X-ray probe pulse follows the X-ray-induced dynamics at another site within the same molecule. Here we show experimental evidence of a hetero-site pump-probe signal. By using two-colour 10-fs X-ray pulses, we are able to observe the femtosecond time dependence for the formation of F ions during the fragmentation of XeF2 molecules following X-ray absorption at the Xe site.

Efficient quantum computing using coherent photon conversion.

PubMed

Langford, N K; Ramelow, S; Prevedel, R; Munro, W J; Milburn, G J; Zeilinger, A

2011-10-12

Single photons are excellent quantum information carriers: they were used in the earliest demonstrations of entanglement and in the production of the highest-quality entanglement reported so far. However, current schemes for preparing, processing and measuring them are inefficient. For example, down-conversion provides heralded, but randomly timed, single photons, and linear optics gates are inherently probabilistic. Here we introduce a deterministic process--coherent photon conversion (CPC)--that provides a new way to generate and process complex, multiquanta states for photonic quantum information applications. The technique uses classically pumped nonlinearities to induce coherent oscillations between orthogonal states of multiple quantum excitations. One example of CPC, based on a pumped four-wave-mixing interaction, is shown to yield a single, versatile process that provides a full set of photonic quantum processing tools. This set satisfies the DiVincenzo criteria for a scalable quantum computing architecture, including deterministic multiqubit entanglement gates (based on a novel form of photon-photon interaction), high-quality heralded single- and multiphoton states free from higher-order imperfections, and robust, high-efficiency detection. It can also be used to produce heralded multiphoton entanglement, create optically switchable quantum circuits and implement an improved form of down-conversion with reduced higher-order effects. Such tools are valuable building blocks for many quantum-enabled technologies. Finally, using photonic crystal fibres we experimentally demonstrate quantum correlations arising from a four-colour nonlinear process suitable for CPC and use these measurements to study the feasibility of reaching the deterministic regime with current technology. Our scheme, which is based on interacting bosonic fields, is not restricted to optical systems but could also be implemented in optomechanical, electromechanical and superconducting systems with extremely strong intrinsic nonlinearities. Furthermore, exploiting higher-order nonlinearities with multiple pump fields yields a mechanism for multiparty mediation of the complex, coherent dynamics.

Ultra-broadband infrared pump-probe spectroscopy using synchrotron radiation and a tuneable pump.

PubMed

Carroll, Lee; Friedli, Peter; Lerch, Philippe; Schneider, Jörg; Treyer, Daniel; Hunziker, Stephan; Stutz, Stefan; Sigg, Hans

2011-06-01

Synchrotron infrared sources have become popular mainly because of their excellent broadband brilliance, which enables spectroscopically resolved spatial-mapping of stationary objects at the diffraction limit. In this article we focus on an often-neglected further advantage of such sources - their unique time-structure - to bring such broadband spectroscopy to the time domain, for studying dynamic phenomenon down to the 100 ps limit. We describe the ultra-broadband (12.5 to 1.1 μm) Fourier transform pump-probe setup, for condensed matter transmission- and reflection-spectroscopy, installed at the X01DC infrared beam-line of the Swiss Light Source (SLS). The optical pump consists of a widely tuneable 100 ps 1 kHz laser system, covering 94% of the 16 to 1.1 μm range. A thorough description of the system is given, including (i) the vector-modulator providing purely electronic tuning of the pump-probe overlap up to 1 ms with sub-ps time resolution, (ii) the 500 MHz data acquisition system interfaced with the experimental physics and industrial control system (EPICS) based SLS control system for consecutive pulse sampling, and (iii) the step-scan time-slice Fourier transform scheme for simultaneous recording of the dual-channel pumped, un-pumped, and difference spectra. The typical signal/noise ratio of a single interferogram in a 100 ps time slice is 300 (measured during one single 140 s TopUp period). This signal/noise ratio is comparable to that of existing gated Globar pump-probe Fourier transform spectroscopy, but brings up to four orders of magnitude better time resolution. To showcase the utility of broadband pump-probe spectroscopy, we investigate a Ge-on-Si material system similar to that in which optically pumped direct-gap lasing was recently reported. We show that the mid-infrared reflection-spectra can be used to determine the optically injected carrier density, while the mid- and near-infrared transmission-spectra can be used to separate the strong pump-induced absorption and inversion processes present at the direct-gap energy. © 2011 American Institute of Physics

Laser-induced nonlinear crystalline waveguide on glass fiber format and diode-pumped second harmonic generation

NASA Astrophysics Data System (ADS)

Shi, Jindan; Feng, Xian

2018-03-01

We report a diode pumped self-frequency-doubled nonlinear crystalline waveguide on glass fiber. A ribbon fiber has been drawn on the glass composition of 50GeO2-25B2O3-25(La,Yb)2O3. Surface channel waveguides have been written on the surface of the ribbon fiber, using space-selective laser heating method with the assistance of a 244 nm CW UV laser. The Raman spectrum of the written area indicates that the waveguide is composed of structure-deformed nonlinear (La,Yb)BGeO5 crystal. The laser-induced surface wavy cracks have also been observed and the forming mechanism of the wavy cracks has been discussed. Efficient second harmonic generation has been observed from the laser-induced crystalline waveguide, using a 976 nm diode pump. 13 μW of 488 nm output has been observed from a 17 mm long waveguide with 26.0 mW of launched diode pump power, corresponding to a normalized conversion efficiency of 4.4%W-1.

Superluminescence from an optically pumped molecular tunneling junction by injection of plasmon induced hot electrons

PubMed Central

Braun, Kai; Wang, Xiao; Kern, Andreas M; Adler, Hilmar; Peisert, Heiko; Chassé, Thomas; Zhang, Dai

2015-01-01

Summary Here, we demonstrate a bias-driven superluminescent point light-source based on an optically pumped molecular junction (gold substrate/self-assembled molecular monolayer/gold tip) of a scanning tunneling microscope, operating at ambient conditions and providing almost three orders of magnitude higher electron-to-photon conversion efficiency than electroluminescence induced by inelastic tunneling without optical pumping. A positive, steadily increasing bias voltage induces a step-like rise of the Stokes shifted optical signal emitted from the junction. This emission is strongly attenuated by reversing the applied bias voltage. At high bias voltage, the emission intensity depends non-linearly on the optical pump power. The enhanced emission can be modelled by rate equations taking into account hole injection from the tip (anode) into the highest occupied orbital of the closest substrate-bound molecule (lower level) and radiative recombination with an electron from above the Fermi level (upper level), hence feeding photons back by stimulated emission resonant with the gap mode. The system reflects many essential features of a superluminescent light emitting diode. PMID:26171286

Gas Requirements in Pressurized Transfer of Liquid Hydrogen

NASA Technical Reports Server (NTRS)

Gluck, D. F.; Kline, J. F.

1961-01-01

Of late, liquid hydrogen has become a very popular fuel for space missions. It is being used in such programs as Centaur and Saturn. Furthermore, hydrogen is the ideal working fluid for nuclear powered space vehicles currently under development. In these applications, liquid hydrogen fuel is generally transferred to the combustion chamber by a combination of pumping and pressurization. The pump forces the liquid propellant from the fuel tank to the combustion chamber; gaseous pressurant holds tank pressure sufficiently high to prevent cavitation at the pump inlet and to maintain the structural rigidity of the tank. The pressurizing system, composed of pressurant, tankage, and associated hardware can be a large portion of the total vehicle weight. Pressurant weight can be reduced by introducing the pressurizing gas at temperatures substantially greater than those of liquid hydrogen. Heat and mass transfer processes thereby induced complicate gas requirements during discharge. These requirements must be known to insure proper design of the pressurizing system. The aim of this paper is to develop from basic mass and energy transfer processes a general method to predict helium and hydrogen gas usage for the pressurized transfer of liquid hydrogen. This required an analytical and experimental investigation, the results of which are described in this paper.

Development of a standardized, citywide process for managing smart-pump drug libraries.

PubMed

Walroth, Todd A; Smallwood, Shannon; Arthur, Karen; Vance, Betsy; Washington, Alana; Staublin, Therese; Haslar, Tammy; Reddan, Jennifer G; Fuller, James

2018-06-15

Development and implementation of an interprofessional consensus-driven process for review and optimization of smart-pump drug libraries and dosing limits are described. The Indianapolis Coalition for Patient Safety (ICPS), which represents 6 Indianapolis-area health systems, identified an opportunity to reduce clinically insignificant alerts that smart infusion pumps present to end users. Through a consensus-driven process, ICPS aimed to identify best practices to implement at individual hospitals in order to establish specific action items for smart-pump drug library optimization. A work group of pharmacists, nurses, and industrial engineers met to evaluate variability within and lack of scrutiny of smart-pump drug libraries. The work group used Lean Six Sigma methodologies to generate a list of key needs and barriers to be addressed in process standardization. The group reviewed targets for smart-pump drug library optimization, including dosing limits, types of alerts reviewed, policies, and safety best practices. The work group also analyzed existing processes at each site to develop a final consensus statement outlining a model process for reviewing alerts and managing smart-pump data. Analysis of the total number of alerts per device across ICPS-affiliated health systems over a 4-year period indicated a 50% decrease (from 7.2 to 3.6 alerts per device per month) after implementation of the model by ICPS member organizations. Through implementation of a standardized, consensus-driven process for smart-pump drug library optimization, ICPS member health systems reduced clinically insignificant smart-pump alerts. Copyright © 2018 by the American Society of Health-System Pharmacists, Inc. All rights reserved.

Pump-probe spectroscopy in organic semiconductors: monitoring fundamental processes of relevance in optoelectronics.

PubMed

Cabanillas-Gonzalez, Juan; Grancini, Giulia; Lanzani, Guglielmo

2011-12-08

In this review we highlight the contribution of pump-probe spectroscopy to understand elementary processes taking place in organic based optoelectronic devices. The techniques described in this article span from conventional pump-probe spectroscopy to electromodulated pump-probe and the state-of-the-art confocal pump-probe microscopy. The article is structured according to three fundamental processes (optical gain, charge photogeneration and charge transport) and the contribution of these techniques on them. The combination of these tools opens up new perspectives for assessing the role of short-lived excited states on processes lying underneath organic device operation. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Efflux Pump Gene Expression in Multidrug-Resistant Mycobacterium tuberculosis Clinical Isolates

PubMed Central

Jiang, Yi; Wei, Jianhao; Zhao, Li-li; Zhao, Xiuqin; Lu, Jianxin; Wan, Kanglin

2015-01-01

Isoniazid (INH) and rifampicin (RIF) are the two most effective drugs in tuberculosis therapy. Understanding the molecular mechanisms of resistance to these two drugs is essential to quickly diagnose multidrug-resistant (MDR) tuberculosis and extensive drug-resistant tuberculosis. Nine clinical Mycobacterium tuberculosis isolates resistant to only INH and RIF and 10 clinical pan-sensitive isolates were included to evaluate the expression of 20 putative drug efflux pump genes and sequence mutations in rpoB (RIF), katG (INH), the inhA promoter (INH), and oxyR-ahpC (INH). Nine and three MDR isolates were induced to overexpress efflux pump genes by INH and RIF, respectively. Eight and two efflux pump genes were induced to overexpress by INH and RIF in MDR isolates, respectively. drrA, drrB, efpA, jefA (Rv2459), mmr, Rv0849, Rv1634, and Rv1250 were overexpressed under INH or RIF stress. Most efflux pump genes were overexpressed under INH stress in a MDR isolates that carried the wild-type katG, inhA, and oxyR-ahpC associated with INH resistance than in those that carried mutations. The expression levels of 11 genes (efpA, Rv0849, Rv1250, P55 (Rv1410c), Rv1634, Rv2994, stp, Rv2459, pstB, drrA, and drrB) without drug inducement were significantly higher (P < 0.05) in nine MDR isolates than in 10 pan-sensitive isolates. In conclusion, efflux pumps may play an important role in INH acquired resistance in MDR M. tuberculosis, especially in those strains having no mutations in genes associated with INH resistance; basal expression levels of some efflux pump genes are higher in MDR isolates than in pan-sensitive isolates and the basal expressional differences may be helpful to diagnose and treat resistant tuberculosis. PMID:25695504

Temporal reflection as a spectral-broadening mechanism in dual-pumped dispersion-decreasing fibers and its connection to dispersive waves

NASA Astrophysics Data System (ADS)

Antikainen, Aku; Arteaga-Sierra, Francisco R.; Agrawal, Govind P.

2017-03-01

We show that temporal reflections off a moving refractive index barrier play a major role in the spectral broadening of a dual-wavelength input inside a highly nonlinear, dispersion-decreasing fiber. We also find that a recently developed linear theory of temporal reflections works well in predicting the reflected frequencies. Successive temporal reflections from multiple closely spaced solitons create a blueshifted spectral band, while continuous narrowing of solitons inside the dispersion-decreasing fiber enhances Raman-induced redshifts, leading to supercontinuum generation at relatively low pump powers. We also show how dispersive wave emission can be considered a special case of the more general process of temporal reflections. Hence our findings have implications on all systems able to support solitons.

Effect of pump polarization direction on power characteristics in monolithic microchip Nd:YAG dual-frequency laser.

PubMed

Chen, Hao; Zhang, Shulian; Tan, Yidong

2016-04-10

The pump polarization direction can greatly influence the characteristics of the laser diode end-pumped monolithic microchip Nd:YAG dual-frequency laser. We experimentally observe the lasing thresholds and the optical powers of two splitting modes versus the pump polarization direction. The effect of the pump-induced gain anisotropy on the mode oscillation sequence is analyzed. And the effect on the intensities of these modes is also proved with a rate equation model. This study contributes to the improvement of the stability and the reliability of the Nd:YAG dual-frequency laser.

Field Effect Flow Control in a Polymer T-Intersection Microfluidic Network

NASA Technical Reports Server (NTRS)

Sniadecki, Nathan J.; Chang, Richard; Beamesderfer, Mike; Lee, Cheng S.; DeVoe, Don L.

2003-01-01

We present a study of induced pressure pumping in a polymer microchannel due to differential electroosmotic flow @OF) rates via field-effect flow control (FEFC). The experimental results demonstrate that the induced pressure pumping is dependent on the distance of the FEFC gate from the cathodic gate. A proposed flow model based on a linearly-decaying zeta potential profile is found to successfully predict experimental trends.

Resonant intersubband polariton-LO phonon scattering in an optically pumped polaritonic device

NASA Astrophysics Data System (ADS)

Manceau, J.-M.; Tran, N.-L.; Biasiol, G.; Laurent, T.; Sagnes, I.; Beaudoin, G.; De Liberato, S.; Carusotto, I.; Colombelli, R.

2018-05-01

We report experimental evidence of longitudinal optical (LO) phonon-intersubband polariton scattering processes under resonant injection of light. The scattering process is resonant with both the initial (upper polariton) and final (lower polariton) states and is induced by the interaction of confined electrons with longitudinal optical phonons. The system is optically pumped with a mid-IR laser tuned between 1094 cm-1 and 1134 cm-1 (λ = 9.14 μm and λ = 8.82 μm). The demonstration is provided for both GaAs/AlGaAs and InGaAs/AlInAs doped quantum well systems whose intersubband plasmon lies at a wavelength of ≈10 μm. In addition to elucidating the microscopic mechanism of the polariton-phonon scattering, it is found to differ substantially from the standard single particle electron-LO phonon scattering mechanism, and this work constitutes an important step towards the hopefully forthcoming demonstration of an intersubband polariton laser.

Fundamental Study of Nuclear Pumped Laser Plasmas.

DTIC Science & Technology

1980-12-23

PUMPED DYE LASER PMT PUMPING/ GAS HAND- LING SYSTEM ANODE SIGNAL TO SCREEN ROOM FIGURE 13 EXPERIMENTAL APPARATUS FROM ANODE OF PMT SCREEN ROOM...and G.A. Zdasiuk, " Laser Induced Collisional and Radiative Energy Transfer’, Proceedings of Laser Spectroscopy IV, June 1979. W. R. Green, M.D. Wright...AD-A130 988 FUNDAMENTAL STUDY 0F NUCLEAR PUMPED LASER PLASMAS(U) 1/ MIAMI UNIV OXFORD UHDi EPT OF PHYSIS Cs W DOWNES ET AL 23 DEC AS OASGAS 7A C OSAN

Twisting Anderson pseudospins with light: Quench dynamics in THz-pumped BCS superconductors

NASA Astrophysics Data System (ADS)

Chou, Yang-Zhi; Liao, Yunxiang; Foster, Matthew

We study the preparation and the detection of coherent far-from-equilibrium BCS superconductor dynamics in THz pump-probe experiments. In a recent experiment, an intense monocycle THz pulse with center frequency ω = Δ was injected into a superconductor with BCS gap Δ the post-pump evolution was detected via the optical conductivity. It was argued that nonlinear coupling of the pump to the Anderson pseudospins of the superconductor induces coherent dynamics of the Higgs mode Δ (t) . We validate this picture in a 2D BCS model with a combination of exact numerics and the Lax reduction, and we compute the dynamical phase diagram. The main effect of the pump is to scramble the orientations of Anderson pseudospins along the Fermi surface by twisting them in the xy-plane. We show that more intense pulses can induce a far-from-equilibrium gapless phase (phase I), originally predicted in the context of interaction quenches. We show that the THz pump can reach phase I at much lower energy densities than an interaction quench, and we demonstrate that Lax reduction provides a quantitative tool for computing coherent BCS dynamics. We also compute the optical conductivity for the states discussed here.

Chilldown study of the single stage inducer test rig

NASA Technical Reports Server (NTRS)

Kimura, L. A.

1972-01-01

Of the six chilldown tests, data from only one could be used for evaluation. During the rest of the chilldown tests, there was leakage hydrogen flow into the pump cavity prior to the initiation of the chilldown test. In all of the tests the hydrogen condition into the pump was probably 100% vapor. The data from this one test, therefore, can be used to compare only the single phase fluid correlation in the analytical pump chilldown model. In general, the actual pump chilled down much faster than predicted by the analytical pump model. There were insufficient data from the test to measure the pump flow rate and pump inlet fluid condition; therefore, these parameters were extrapolated based on related data which were available. However, even with the highest probable flow rate, the pump chilled faster than predicted.

Design and cost analysis of rapid aquifer restoration systems using flow simulation and quadratic programming.

USGS Publications Warehouse

Lefkoff, L.J.; Gorelick, S.M.

1986-01-01

Detailed two-dimensional flow simulation of a complex ground-water system is combined with quadratic and linear programming to evaluate design alternatives for rapid aquifer restoration. Results show how treatment and pumping costs depend dynamically on the type of treatment process, and capacity of pumping and injection wells, and the number of wells. The design for an inexpensive treatment process minimizes pumping costs, while an expensive process results in the minimization of treatment costs. Substantial reductions in pumping costs occur with increases in injection capacity or in the number of wells. Treatment costs are reduced by expansions in pumping capacity or injecion capacity. The analysis identifies maximum pumping and injection capacities.-from Authors

Role of the stimulated radiation of Yb3+ ions in the formation of luminescence of the Y0.8Yb0.2F3:Tm3+ solid solution

NASA Astrophysics Data System (ADS)

Mikheev, A. V.; Kazakov, B. N.

2015-09-01

A new mechanism has been proposed for the transfer of the energy of exciting laser radiation through the donor subsystem (Yb3+) to acceptors (Tm3+), which induces multiphoton transitions in the acceptor subsystem. The coherence of the induced radiation of donors is of key importance in this mechanism. An analytical dependence of the intensity of the up-conversion luminescence of Tm3+ (1G4 → 3H6) ions in the Y0.8Yb0.2F3:Tm3+ system on the pump power at the steady-state excitation by 934-nm infrared radiation of a laser diode has been obtained using the mathematical technique of the theory of Poisson processes. In contrast to known mechanisms, this dependence approximates the experimental dependence well in a wide power range (200-1200 mW). The proposed model is applicable for any system where the energy of pump radiation is transferred to acceptors through the subsystem of donor ions.

355 nm and 1064 nm-pulse mixing to identify the laser-induced damage mechanisms in KDP

NASA Astrophysics Data System (ADS)

Reyné, Stéphane; Duchateau, Guillaume; Natoli, Jean-Yves; Lamaignère, Laurent

2011-02-01

Nanosecond laser-induced damage (LID) in potassium dihydrogen phosphate (KH2PO4 or KDP) remains an issue for light-frequency converters in large-aperture lasers such as NIF (National Ignition Facility, in USA) LMJ (Laser MegaJoule, in France). In the final optic assembly, converters are simultaneously illuminated by multiple wavelengths during the frequency conversion. In this configuration, the damage resistance of the KDP crystals becomes a crucial problem and has to be improved. In this study, we propose a refined investigation about the LID mechanisms involved in the case of a multiple wavelengths combination. Experiments based on an original pump-pump set-up have been carried out in the nanosecond regime on a KDP crystal. In particular, the impact of a simultaneous mixing of 355 nm and 1064 nm pulses has been experimentally studied and compared to a model based on heat transfer, the Mie theory and a Drude model. This study sheds light on the physical processes implied in the KDP laser damage. In particular, a three-photon ionization mechanism is shown to be responsible for laser damage in KDP.

Aquifer geochemistry and effects of pumping on ground-water quality at the Green Belt Parkway Well Field, Holbrook, Long Island, New York

USGS Publications Warehouse

Brown, Craig J.; Colabufo, Steven; Coates, John D.

2002-01-01

Geochemistry, microbiology, and water quality of the Magothy aquifer at a new supply well in Holbrook were studied to help identify factors that contribute to iron-related biofouling of public-supply wells. The organic carbon content of borehole sediments from the screen zone, and the dominant terminal electron-accepting processes (TEAPs), varied by depth. TEAP assays of core sediments indicated that iron reduction, sulfate reduction, and undetermined (possibly oxic) reactions and microbial activity are correlated with organic carbon (lignite) content. The quality of water from this well, therefore, reflects the wide range of aquifer microenvironments at this site.High concentrations of dissolved iron (3.6 to 6.4 micromoles per liter) in water samples from this well indicate that some water is derived from Fe(III)-reducing sediments within the aquifer, but traces of dissolved oxygen indicate inflow of shallow, oxygenated water from shallow units that overlie the local confining units. Water-quality monitoring before and during a 2-day pumping test indicates that continuous pumping from the Magothy aquifer at this site can induce downward flow of shallow, oxygenated water despite the locally confined conditions. Average concentrations of dissolved oxygen are high (5.2 milligrams per liter, or mg/L) in the overlying upper glacial aquifer and at the top of the Magothy aquifer (4.3 mg/L), and low ( < 0.1 mg/L) in the deeper, anaerobic part of the Magothy; average concentrations of phosphate are high (0.4 mg/L) in the upper glacial aquifer and lower (0.008 mg/L) at the top of the Magothy aquifer and in the deeper part of the Magothy (0.013 mg/L). Concentrations of both constituents increased during the 2 days of pumping. The δ34S of sulfate in shallow ground water from observation wells (3.8 to 6.4 per mil) was much heavier than that in the supplywell water (-0.1 per mil) and was used to help identify sources of water entering the supply well. The δ34S of sulfate in a deep observation well adjacent to the supply well increased from 2.4 per mil before pumping to 3.3 per mil after pumping; this confirms that the pumping induced downward migration of water. The lighter δ34S value in the pumped water than in the adjacent observation well probably indicates FeS2 oxidation (which releases light δ34S in adjacent sediments) by the downward flow of oxygenated water.

Protein kinase-dependent oxidative regulation of the cardiac Na+–K+ pump: evidence from in vivo and in vitro modulation of cell signalling

PubMed Central

Galougahi, Keyvan Karimi; Liu, Chia-Chi; Garcia, Alvaro; Fry, Natasha A S; Hamilton, Elisha J; Rasmussen, Helge H; Figtree, Gemma A

2013-01-01

The widely reported stimulation of the cardiac Na+–K+ pump by protein kinase A (PKA) should oppose other effects of PKA to increase contractility of the normal heart. It should also reduce harmful raised myocyte Na+ levels in heart failure, yet blockade of the β1 adrenergic receptor (AR), coupled to PKA signalling, is beneficial. We treated rabbits with the β1 AR antagonist metoprolol to modulate PKA activity and studied cardiac myocytes ex vivo. Metoprolol increased electrogenic pump current (Ip) in voltage clamped myocytes and reduced glutathionylation of the β1 pump subunit, an oxidative modification causally related to pump inhibition. Activation of adenylyl cyclase with forskolin to enhance cAMP synthesis or inclusion of the catalytic subunit of PKA in patch pipette solutions abolished the increase in Ip in voltage clamped myocytes induced by treatment with metoprolol, supporting cAMP/PKA-mediated pump inhibition. Metoprolol reduced myocardial PKA and protein kinase C (PKC) activities, reduced coimmunoprecipitation of cytosolic p47phox and membranous p22phox NADPH oxidase subunits and reduced myocardial O2•−-sensitive dihydroethidium fluorescence. Treatment also enhanced coimmunoprecipitation of the β1 pump subunit with glutaredoxin 1 that catalyses de-glutathionylation. Since angiotensin II induces PKC-dependent activation of NADPH oxidase, we examined the effects of angiotensin-converting enzyme inhibition with captopril. This treatment had no effect on PKA activity but reduced the activity of PKC, reduced β1 subunit glutathionylation and increased Ip. The PKA-induced Na+–K+ pump inhibition we report should act with other mechanisms that enhance contractility of the normal heart but accentuate the harmful effects of raised cytosolic Na+ in the failing heart. This scheme is consistent with the efficacy of β1 AR blockade in the treatment of heart failure. PMID:23587884

Modulated phase matching and high-order harmonic enhancement mediated by the carrier-envelope phase

DOE Office of Scientific and Technical Information (OSTI.GOV)

Faccio, Daniele; CNISM and Department of Physics and Mathematics, Universita dell'Insubria, Via Valleggio 11, I-22100 Como; Serrat, Carles

2010-01-15

The process of high-order harmonic generation in gases is numerically investigated in the presence of a few-cycle pulsed-Bessel-beam pump, featuring a periodic modulation in the peak intensity due to large carrier-envelope-phase mismatch. A two-decade enhancement in the conversion efficiency is observed and interpreted as the consequence of a mechanism known as a nonlinearly induced modulation in the phase mismatch.

Hydrodynamic design of generic pump components

NASA Technical Reports Server (NTRS)

Eastland, A. H. J.; Dodson, H. C.

1991-01-01

Inducer and impellar base geometries were defined for a fuel pump for a generic generator cycle. Blade surface data and inlet flowfield definition are available in sufficient detail to allow computational fluid dynamic analysis of the two components.

Hetero-site-specific X-ray pump-probe spectroscopy for femtosecond intramolecular dynamics

DOE PAGES

Picón, A.; Lehmann, C. S.; Bostedt, C.; ...

2016-05-23

New capabilities at X-ray free-electron laser facilities allow the generation of two-colour femtosecond X-ray pulses, opening the possibility of performing ultrafast studies of X-ray-induced phenomena. Specifically, the experimental realization of hetero-site-specific X-ray-pump/X-ray-probe spectroscopy is of special interest, in which an X-ray pump pulse is absorbed at one site within a molecule and an X-ray probe pulse follows the X-ray-induced dynamics at another site within the same molecule. In this paper, we show experimental evidence of a hetero-site pump-probe signal. By using two-colour 10-fs X-ray pulses, we are able to observe the femtosecond time dependence for the formation of F ionsmore » during the fragmentation of XeF 2 molecules following X-ray absorption at the Xe site.« less

Development of a mercury electromagnetic centrifugal pump for the SNAP-8 refractory boiler development program

NASA Technical Reports Server (NTRS)

Fuller, R. A.; Schnacke, A. W.

1974-01-01

An electromagnetic pump, in which pressure is developed in mercury because of the interaction of the magnetic field and current which flows as a result of the voltage induced in the mercury contained in the pump duct, was developed for the SNAP-8 refractory boiler test facility. Pump performance results are presented for ten duct configurations and two stator sizes. These test results were used to design and fabricate a pump which met the SNAP-8 criteria of 530 psi developed pressure at 12,500 lb/hr. The pump operated continuously for over 13,000 hours without failure or performance degradation. Included in this report are descriptions of the experimental equipment, measurement techniques, all experimental data, and an analysis of the electrical losses in the pump.

Space Station Water Processor Process Pump

NASA Technical Reports Server (NTRS)

Parker, David

1995-01-01

This report presents the results of the development program conducted under contract NAS8-38250-12 related to the International Space Station (ISS) Water Processor (WP) Process Pump. The results of the Process Pumps evaluation conducted on this program indicates that further development is required in order to achieve the performance and life requirements for the ISSWP.

A scenario for magnonic spin-wave traps

PubMed Central

Busse, Frederik; Mansurova, Maria; Lenk, Benjamin; von der Ehe, Marvin; Münzenberg, Markus

2015-01-01

Spatially resolved measurements of the magnetization dynamics on a thin CoFeB film induced by an intense laser pump-pulse reveal that the frequencies of resulting spin-wave modes depend strongly on the distance to the pump center. This can be attributed to a laser generated temperature profile. We determine a shift of 0.5 GHz in the spin-wave frequency due to the spatial thermal profile induced by the femtosecond pump pulse that persists for up to one nanosecond. Similar experiments are presented for a magnonic crystal composed of a CoFeB-film based antidot lattice with a Damon Eshbach mode at the Brillouin zone boundary and its consequences are discussed. PMID:26279466

Centrifugal and Axial Pump Design and Off-Design Performance Prediction

NASA Technical Reports Server (NTRS)

Veres, Joseph P.

1995-01-01

A meanline pump-flow modeling method has been developed to provide a fast capability for modeling pumps of cryogenic rocket engines. Based on this method, a meanline pump-flow code PUMPA was written that can predict the performance of pumps at off-design operating conditions, given the loss of the diffusion system at the design point. The design-point rotor efficiency and slip factors are obtained from empirical correlations to rotor-specific speed and geometry. The pump code can model axial, inducer, mixed-flow, and centrifugal pumps and can model multistage pumps in series. The rapid input setup and computer run time for this meanline pump flow code make it an effective analysis and conceptual design tool. The map-generation capabilities of the code provide the information needed for interfacing with a rocket engine system modeling code. The off-design and multistage modeling capabilities of PUMPA permit the user to do parametric design space exploration of candidate pump configurations and to provide head-flow maps for engine system evaluation.

Downregulation of surface sodium pumps by endocytosis during meiotic maturation of Xenopus laevis oocytes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schmalzing, G.; Eckard, P.; Kroener, S.P.

1990-01-01

During meiotic maturation, plasma membranes of Xenopus laevis oocytes completely lose the capacity to transport Na and K and to bind ouabain. To explore whether the downregulation might be due to an internalization of the sodium pump molecules, the intracellular binding of ouabain was determined. Selective permeabilization of the plasma membrane of mature oocytes (eggs) by digitonin almost failed to disclose ouabain binding sites. However, when the eggs were additionally treated with 0.02% sodium dodecyl sulfate (SDS) to permeabilize inner membranes, all sodium pumps present before maturation were recovered. Phosphorylation by (gamma-32P)ATP combined with SDS-polyacrylamide gel electrophoresis (PAGE) and autoradiographymore » showed that sodium pumps were greatly reduced in isolated plasma membranes of eggs. According to sucrose gradient fractionation, maturation induced a shift of sodium pumps from the plasma membrane fraction to membranes of lower buoyant density with a protein composition different from that of the plasma membrane. Endocytosed sodium pumps identified on the sucrose gradient from (3H)ouabain bound to the cell surface before maturation could be phosphorylated with inorganic (32P)phosphate. The findings suggest that downregulation of sodium pumps during maturation is brought about by translocation of surface sodium pumps to an intracellular compartment, presumably endosomes. This contrasts the mechanism of downregulation of Na-dependent cotransport systems, the activities of which are reduced as a consequence of a maturation-induced depolarization of the membrane without a removal of the corresponding transporter from the plasma membrane.« less

Microscale solution manipulation using photopolymerized hydrogel membranes and induced charge electroosmosis micropumps

NASA Astrophysics Data System (ADS)

Paustian, Joel Scott

Microfluidic technology is playing an ever-expanding role in advanced chemical and biological devices, with diverse applications including medical diagnostics, high throughput research tools, chemical or biological detection, separations, and controlled particle fabrication. Even so, local (microscale) modification of solution properties within microchannels, such as pressure, solute concentration, and voltage remains a challenge, and improved spatiotemporal control would greatly enhance the capabilities of microfluidics. This thesis demonstrates and characterizes two microfluidic tools to enhance local solution control. I first describe a microfluidic pump that uses an electrokinetic effect, Induced-Charge Electroosmosis (ICEO), to generate pressure on-chip. In ICEO, steady flows are driven by AC fields along metal-electrolyte interfaces. I design and microfabricate a pump that exploits this effect to generate on-chip pressures. The ICEO pump is used to drive flow along a microchannel, and the pressure is measured as a function of voltage, frequency, and electrolyte composition. This is the first demonstration of chip-scale flows driven by ICEO, which opens the possibility for ICEO pumping in self-contained microfluidic devices. Next, I demonstrate a method to create thin local membranes between microchannels, which enables local diffusive delivery of solute. These ``Hydrogel Membrane Microwindows'' are made by photopolymerizing a hydrogel which serves as a local ``window'' for solute diffusion and electromigration between channels, but remains a barrier to flow. I demonstrate three novel experimental capabilities enabled by the hydrogel membranes: local concentration gradients, local electric currents, and rapid diffusive composition changes. I conclude by applying the hydrogel membranes to study solvophoresis, the migration of particles in solvent gradients. Solvent gradients are present in many chemical processes, but migration of particles within these gradients is not well understood. An improved understanding would allow solvophoresis to be engineered (e.g. for coatings and thin film deposition) or reduced (e.g. in fouling processes during reactions and separations). Toward this end, I perform velocity measurements of colloidal particles at various ethanol-water concentrations and gradient strengths. The velocity was found to depend on the mole fraction via the equation u = DSP▿ln X, where u is the velocity, DSP is the mobility, and X is the ethanol mole fraction.

Polarization-controlled optimal scatter suppression in transient absorption spectroscopy

PubMed Central

Malý, Pavel; Ravensbergen, Janneke; Kennis, John T. M.; van Grondelle, Rienk; Croce, Roberta; Mančal, Tomáš; van Oort, Bart

2017-01-01

Ultrafast transient absorption spectroscopy is a powerful technique to study fast photo-induced processes, such as electron, proton and energy transfer, isomerization and molecular dynamics, in a diverse range of samples, including solid state materials and proteins. Many such experiments suffer from signal distortion by scattered excitation light, in particular close to the excitation (pump) frequency. Scattered light can be effectively suppressed by a polarizer oriented perpendicular to the excitation polarization and positioned behind the sample in the optical path of the probe beam. However, this introduces anisotropic polarization contributions into the recorded signal. We present an approach based on setting specific polarizations of the pump and probe pulses, combined with a polarizer behind the sample. Together, this controls the signal-to-scatter ratio (SSR), while maintaining isotropic signal. We present SSR for the full range of polarizations and analytically derive the optimal configuration at angles of 40.5° between probe and pump and of 66.9° between polarizer and pump polarizations. This improves SSR by (or compared to polarizer parallel to probe). The calculations are validated by transient absorption experiments on the common fluorescent dye Rhodamine B. This approach provides a simple method to considerably improve the SSR in transient absorption spectroscopy. PMID:28262765

Measure Guideline. Replacing Single-Speed Pool Pumps with Variable Speed Pumps for Energy Savings

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hunt, A.; Easley, S.

2012-05-01

This measure guideline evaluates potential energy savings by replacing traditional single-speed pool pumps with variable speed pool pumps, and provides a basic cost comparison between continued uses of traditional pumps verses new pumps. A simple step-by-step process for inspecting the pool area and installing a new pool pump follows.

Measure Guideline: Replacing Single-Speed Pool Pumps with Variable Speed Pumps for Energy Savings

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hunt, A.; Easley, S.

2012-05-01

The report evaluates potential energy savings by replacing traditional single-speed pool pumps with variable speed pool pumps, and provide a basic cost comparison between continued uses of traditional pumps verses new pumps. A simple step-by-step process for inspecting the pool area and installing a new pool pump follows.

Use of ultrafast dispersed pump-dump-probe and pump-repump-probe spectroscopies to explore the light-induced dynamics of peridinin in solution.

PubMed

Papagiannakis, Emmanouil; Vengris, Mikas; Larsen, Delmar S; van Stokkum, Ivo H M; Hiller, Roger G; van Grondelle, Rienk

2006-01-12

Optical pump-induced dynamics of the highly asymmetric carotenoid peridinin in methanol was studied by dispersed pump-probe, pump-dump-probe, and pump-repump-probe transient absorption spectroscopy in the visible region. Dispersed pump-probe measurements show that the decay of the initially excited S2 state populates two excited states, the S1 and the intramolecular charge-transfer (ICT) state, at a ratio determined by the excitation wavelength. The ensuing spectral evolution occurs on the time scale of a few picoseconds and suggests the equilibration of these states. Dumping the stimulated emission of the ICT state with an additional 800-nm pulse after 400- and 530-nm excitation preferentially removes the ICT state contribution from the broad excited-state absorption, allowing for its spectral characterization. At the same time, an unrelaxed ground-state species, which has a subpicosecond lifetime, is populated. The application of the 800-nm pulse at early times, when the S2 state is still populated, led to direct generation of the peridinin cation, observed for the first time in a transient absorption experiment. The excited and ground electronic states manifold of peridinin has been reconstructed using target analysis; this approach combined with the measured multipulse spectroscopic data allows us to estimate the spectra and time scales of the corresponding transient states.

Hydraulic induced instability on a vertical service

NASA Technical Reports Server (NTRS)

Bosmans, R. F.

1985-01-01

The case history contained provides insight toward the mechanical and hydraulic behavior of a vertical pump. It clearly demonstrates the need for measurements on the rotor at or near the impeller area. The results are reported of an analysis on a service water pump. This pump is typical of the water pumps used throughout the power generation industry. Although little is known of the mechanical behavior of vertical pumps because of difficulty in modeling the rotor system, recent developments in the application of submersible proximity transducers have made possible the measurement of pump dynamics under operating conditions. The purpose of this study was to determine the proper selection and installation of vibration-monitoring transducers as well as to measure the effects of imbalance, misalignment, and hydraulics on the performance and reliability of vertical pumps. In addition, the cause of shaft failures on this pump was to be determined.

UV laser interaction with a fluorescent dye solution studied using pulsed digital holography.

PubMed

Amer, Eynas; Gren, Per; Sjödahl, Mikael

2013-10-21

A frequency tripled Q-switched Nd-YAG laser (wavelength 355 nm, pulse duration 12 ns) has been used to pump Coumarin 153 dye solved in ethanol. Simultaneously, a frequency doubled pulse (532 nm) from the same laser is used to probe the solvent perpendicularly resulting in a gain through stimulated laser induced fluorescence (LIF) emission. The resulting gain of the probe beam is recorded using digital holography by blending it with a reference beam on the detector. Two digital holograms without and with the pump beam were recorded. Intensity maps were calculated from the recorded digital holograms and used to calculate the gain of the probe beam due to the stimulated LIF. In addition numerical data of the local temperature rise was calculated from the corresponding phase maps using Radon inversion. It was concluded that about 15% of the pump beam energy is transferred to the dye solution as heat while the rest is consumed in the radiative process. The results show that pulsed digital holography is a promising technique for quantitative study of fluorescent species.

Pulsed photothermal interferometry for spectroscopic gas detection with hollow-core optical fibre

PubMed Central

Lin, Yuechuan; Jin, Wei; Yang, Fan; Ma, Jun; Wang, Chao; Ho, Hoi Lut; Liu, Yang

2016-01-01

Gas detection with hollow-core photonic bandgap fibre (HC-PBF) and pulsed photothermal (PT) interferometry spectroscopy are studied theoretically and experimentally. A theoretical model is developed and used to compute the gas-absorption-induced temperature and phase modulation in a HC-PBF filled with low-concentration of C2H2 in nitrogen. The PT phase modulation dynamics for different pulse duration, peak power and energy of pump beam are numerically modelled, which are supported by the experimental results obtained around the P(9) absorption line of C2H2 at 1530.371 nm. Thermal conduction is identified as the main process responsible for the phase modulation dynamics. For a constant peak pump power level, the phase modulation is found to increase with pulse duration up to ~1.2 μs, while it increases with decreasing pulse duration for a constant pulse energy. It is theoretically possible to achieve ppb level detection of C2H2 with ~1 m length HC-PBF and a pump beam with ~10 ns pulse duration and ~100 nJ pulse energy. PMID:28009011

Pulsed photothermal interferometry for spectroscopic gas detection with hollow-core optical fibre.

PubMed

Lin, Yuechuan; Jin, Wei; Yang, Fan; Ma, Jun; Wang, Chao; Ho, Hoi Lut; Liu, Yang

2016-12-23

Gas detection with hollow-core photonic bandgap fibre (HC-PBF) and pulsed photothermal (PT) interferometry spectroscopy are studied theoretically and experimentally. A theoretical model is developed and used to compute the gas-absorption-induced temperature and phase modulation in a HC-PBF filled with low-concentration of C 2 H 2 in nitrogen. The PT phase modulation dynamics for different pulse duration, peak power and energy of pump beam are numerically modelled, which are supported by the experimental results obtained around the P(9) absorption line of C 2 H 2 at 1530.371 nm. Thermal conduction is identified as the main process responsible for the phase modulation dynamics. For a constant peak pump power level, the phase modulation is found to increase with pulse duration up to ~1.2 μs, while it increases with decreasing pulse duration for a constant pulse energy. It is theoretically possible to achieve ppb level detection of C 2 H 2 with ~1 m length HC-PBF and a pump beam with ~10 ns pulse duration and ~100 nJ pulse energy.

Nonlinear ultrasonic wave modulation for online fatigue crack detection

NASA Astrophysics Data System (ADS)

Sohn, Hoon; Lim, Hyung Jin; DeSimio, Martin P.; Brown, Kevin; Derriso, Mark

2014-02-01

This study presents a fatigue crack detection technique using nonlinear ultrasonic wave modulation. Ultrasonic waves at two distinctive driving frequencies are generated and corresponding ultrasonic responses are measured using permanently installed lead zirconate titanate (PZT) transducers with a potential for continuous monitoring. Here, the input signal at the lower driving frequency is often referred to as a 'pumping' signal, and the higher frequency input is referred to as a 'probing' signal. The presence of a system nonlinearity, such as a crack formation, can provide a mechanism for nonlinear wave modulation, and create spectral sidebands around the frequency of the probing signal. A signal processing technique combining linear response subtraction (LRS) and synchronous demodulation (SD) is developed specifically to extract the crack-induced spectral sidebands. The proposed crack detection method is successfully applied to identify actual fatigue cracks grown in metallic plate and complex fitting-lug specimens. Finally, the effect of pumping and probing frequencies on the amplitude of the first spectral sideband is investigated using the first sideband spectrogram (FSS) obtained by sweeping both pumping and probing signals over specified frequency ranges.

78 FR 62322 - Hydropower Regulatory Efficiency Act of 2013; Notice of Rescheduled Two-Year Licensing Process...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-16

... at non-powered dams and closed-loop pumped storage projects in compliance with section 6 of the... process for licensing hydropower development at non-powered dams and closed-loop pumped storage projects...-powered dam versus closed- loop pumped storage) affect the steps included in a two-year process? 3.9...

Vacuum pumps and systems: A review of current practice

NASA Technical Reports Server (NTRS)

Giles, Stuart

1986-01-01

A review of the fundamental characteristics of the many types of vacuum pumps and vacuum pumping systems is given. The optimum pumping range, relative cost, performance limitations, maintenance problems, system operating costs and similar subjects are discussed. Experiences from the thin film deposition, chemical processing, material handling, food processing and other industries, as well as space simulation are used to support conclusions and recommendations.

Thermally induced optical deformation of a Nd:YVO4 active disk under the action of multi-beam spatially periodic diode pumping

NASA Astrophysics Data System (ADS)

Guryev, D. A.; Nikolaev, D. A.; Tsvetkov, V. B.; Shcherbakov, I. A.

2018-05-01

A study of how the transverse distribution of an optical path changes in a Nd:YVO4 active disk was carried out in a ten-beam spatially periodic diode pumping in the one-dimensional case. The pumping beams’ transverse dimensions were comparable with the distances between them. The investigations were carried out using laser interferometry methods. It was found that the optical thickness changing in the active disk along the line of pumping spots was well described by a Gaussian function.

Diode-Laser Pumped Far-Infrared Local Oscillator Based on Semiconductor Quantum Wells

NASA Technical Reports Server (NTRS)

Kolokolov, K.; Li, J.; Ning, C. Z.; Larrabee, D. C.; Tang, J.; Khodaparast, G.; Kono, J.; Sasa, S.; Inoue, M.; Biegel, Bryan A. (Technical Monitor)

2002-01-01

The contents include: 1) Tetrahertz Field: A Technology Gap; 2) Existing THZ Sources and Shortcomings; 3) Applications of A THZ Laser; 4) Previous Optical Pumped LW Generations; 5) Optically Pumped Sb based Intersubband Generation Whys; 6) InGaAs/InP/AlAsSb QWs; 7) Raman Enhanced Optical Gain; 8) Pump Intensity Dependence of THZ Gain; 9) Pump-Probe Interaction Induced Raman Shift; 10) THZ Laser Gain in InGaAs/InP/AlAsSb QWs; 11) Diode-Laser Pumped Difference Frequency Generation (InGaAs/InP/AlAsSb QWs); 12) 6.1 Angstrom Semiconductor Quantum Wells; 13) InAs/GaSb/AlSb Nanostructures; 14) InAs/AlSb Double QWs: DFG Scheme; 15) Sb-Based Triple QWs: Laser Scheme; and 16) Exciton State Pumped THZ Generation. This paper is presented in viewgraph form.

Using failure mode and effects analysis to plan implementation of smart i.v. pump technology.

PubMed

Wetterneck, Tosha B; Skibinski, Kathleen A; Roberts, Tanita L; Kleppin, Susan M; Schroeder, Mark E; Enloe, Myra; Rough, Steven S; Hundt, Ann Schoofs; Carayon, Pascale

2006-08-15

Failure mode and effects analysis (FMEA) was used to evaluate a smart i.v. pump as it was implemented into a redesigned medication-use process. A multidisciplinary team conducted a FMEA to guide the implementation of a smart i.v. pump that was designed to prevent pump programming errors. The smart i.v. pump was equipped with a dose-error reduction system that included a pre-defined drug library in which dosage limits were set for each medication. Monitoring for potential failures and errors occurred for three months postimplementation of FMEA. Specific measures were used to determine the success of the actions that were implemented as a result of the FMEA. The FMEA process at the hospital identified key failure modes in the medication process with the use of the old and new pumps, and actions were taken to avoid errors and adverse events. I.V. pump software and hardware design changes were also recommended. Thirteen of the 18 failure modes reported in practice after pump implementation had been identified by the team. A beneficial outcome of FMEA was the development of a multidisciplinary team that provided the infrastructure for safe technology implementation and effective event investigation after implementation. With the continual updating of i.v. pump software and hardware after implementation, FMEA can be an important starting place for safe technology choice and implementation and can produce site experts to follow technology and process changes over time. FMEA was useful in identifying potential problems in the medication-use process with the implementation of new smart i.v. pumps. Monitoring for system failures and errors after implementation remains necessary.

Rotary piston blood pumps: past developments and future potential of a unique pump type.

PubMed

Wappenschmidt, Johannes; Autschbach, Rüdiger; Steinseifer, Ulrich; Schmitz-Rode, Thomas; Margreiter, Raimund; Klima, Günter; Goetzenich, Andreas

2016-08-01

The design of implantable blood pumps is either based on displacement pumps with membranes or rotary pumps. Both pump types have limitations to meet the clinical requirements. Rotary piston blood pumps have the potential to overcome these limitations and to merge the benefits. Compared to membrane pumps, they are smaller and with no need for wear-affected membranes and valves. Compared to rotary pumps, the blood flow is pulsatile instead of a non-physiological continuous flow. Furthermore, the risk of flow-induced blood damage and platelet activation may be reduced due to low shear stress to the blood. The past developments of rotary piston blood pumps are summarized and the main problem for long-term application is identified: insufficient seals. A new approach with seal-less drives is proposed and current research on a simplified rotary piston design is presented. Expert commentary: The development of blood pumps focuses mainly on the improvement of rotary pumps. However, medical complications indicate that inherent limitations of this pump type remain and restrict the next substantial step forward in the therapy of heart failure patients. Thus, research on different pump types is reasonable. If the development of reliable drives and bearings succeeds, rotary piston blood pumps become a promising alternative.

Pump-probe imaging of the fs-ps-ns dynamics during femtosecond laser Bessel beam drilling in PMMA.

PubMed

Yu, Yanwu; Jiang, Lan; Cao, Qiang; Xia, Bo; Wang, Qingsong; Lu, Yongfeng

2015-12-14

A pump-probe shadowgraph imaging technique was used to reveal the femtosecond-picosecond-nanosecond multitimescale fundamentals of high-quality, high-aspect-ratio (up to 287:1) microhole drilling in poly-methyl-meth-acrylate (PMMA) by a single-shot femtosecond laser Bessel beam. The propagation of Bessel beam in PMMA (at 1.98 × 10⁸ m/s) and it induced cylindrical pressure wave expansion (at 3000-3950 m/s in radius) were observed during drilling processes. Also, it was unexpectedly found that the expansion of the cylindrical pressure wave in PMMA showed a linear relation with time and was insensitive to the laser energy fluctuation, quite different from the case in air. It was assumed that the energy insensitivity was due to the anisotropy of wave expansion in PMMA and the ambient air.

Evaluation of System Architectures for the Army Aviation Ground Power Unit

DTIC Science & Technology

2014-12-01

this state of operation induces wear that reduces pump life. Variable capacity control methods using a constant displacement pump are drive speed...options for use with constant displacement pumps, the fluid or magnetic coupling devices are the most attractive. Variable frequency control cannot...compressor prior to the combustor. The cmTent system turbine exhaust temperature controls to 1250°F, much higher than the compressor exit

Experimental investigation of the effect of pump incoherence on nonlinear pump spectral broadening and continuous-wave supercontinuum generation

NASA Astrophysics Data System (ADS)

Martin-Lopez, S.; Carrasco-Sanz, A.; Corredera, P.; Abrardi, L.; Hernanz, M. L.; Gonzalez-Herraez, M.

2006-12-01

The development of high-power cw fiber lasers has triggered a great interest in the phenomena of nonlinear pump spectral broadening and cw supercontinuum generation. These effects have very convenient applications in Raman amplification, optical fiber metrology, and fiber sensing. In particular, it was recently shown that pump incoherence has a strong impact in these processes. We study experimentally the effect of pump incoherence in nonlinear pump spectral broadening and cw supercontinuum generation in optical fibers. We show that under certain experimental conditions an optimum degree of pump incoherence yields the best performance in the broadening process. We qualitatively explain these results, and we point out that these results may have important implications in cw supercontinuum optimization.

Water Flow Performance of a Superscale Model of the Fastrac Liquid Oxygen Pump

NASA Technical Reports Server (NTRS)

Skelley, Stephen; Zoladz, Thomas

1999-01-01

As part of the National Aeronautics and Space Administration's ongoing effort to lower the cost of access to space, the Marshall Space Flight Center has developed a rocket engine with 60,000 pounds of thrust for use on the Reusable Launch Vehicle technology demonstrator slated for launch in 2000. This gas generator cycle engine, known as the Fastrac engine, uses liquid oxygen and RP-1 for propellants and includes single stage liquid oxygen and RP-1 pumps and a single stage supersonic turbine on a common shaft. The turbopump design effort included the first use and application of new suction capability prediction codes and three-dimensional blade generation codes in an attempt to reduce the turbomachinery design and certification costs typically associated with rocket engine development. To verify the pump's predicted cavitation performance, a water flow test of a superscale model of the Fastrac liquid oxygen pump was conducted to experimentally evaluate the liquid oxygen pump's performance at and around the design point. The water flow test article replicated the flow path of the Fastrac liquid oxygen pump in a 1.582x scale model, including scaled seal clearances for correct leakage flow at a model operating speed of 5000 revolutions per minute. Flow entered the 3-blade axial-flow inducer, transitioned to a shrouded, 6-blade radial impeller, and discharged into a vaneless radial diffuser and collection volute. The test article included approximately 50 total and static pressure measurement locations as well as flush-mounted, high frequency pressure transducers for complete mapping of the pressure environment. The primary objectives of the water flow test were to measure the steady-state and dynamic pressure environment of the liquid oxygen pump versus flow coefficient, suction specific speed, and back face leakage flow rate. Results showed excellent correlation between the predicted and experimentally measured pump head rise at low suction specific speeds. Likewise, only small circumferential variations in steady-state impeller exit and radial diffuser pressure distributions were observed from 80% to 120% of the design flow coefficient, matching the computational predictions and confirming that the integrated design approach has minimized any exit volute-induced distortions. The test article exhibited suction performance trends typically observed in inducer designs with virtually constant head rise with decreasing inlet pressure until complete pump head breakdown. Unfortunately, the net positive suction head at 3% head fall-off occurred far below that predicted at all tested flow coefficients, resulting in a negative net positive suction head margin at the design point in water. Additional testing to map the unsteady pressure environment was conducted and interesting rotating phenomena at the inducer inlet were observed. These rotating phenomena's cell numbers, direction, and speed were correlated with pump operating parameters. The impact of the unsteady phenomena and their corresponding energy losses on the unexpectedly poor pump performance is also discussed.

Accelerations induced by body motions during snow skiing

NASA Astrophysics Data System (ADS)

Mote, C. D.; Louie, J. K.

1983-05-01

Work done by the snow skier during pumping and rocking the center of mass can result in significant accelerations. Pumping and rocking strategies maximizing the velocity of a particle over undulating snow surfaces have been investigated in this paper. The prescribed motions included translation of the particle mass radially from a point contact with the snow surface and rocking of the point contact forward and backward in the vertical plane. The mechanics of the induced velocity variations and the expected magnitude of the velocity variation were of primary interest. The equations of motion were integrated numerically to determine skier-ski model velocity. Positive and negative variations in velocity from 10% to 100% were predicted with pumping strategies over distances of 10-15 m.

Effect of an ultrafast laser induced plasma on a relativistic electron beam to determine temporal overlap in pump-probe experiments.

PubMed

Scoby, Cheyne M; Li, R K; Musumeci, P

2013-04-01

In this paper we report on a simple and robust method to measure the absolute temporal overlap of the laser and the electron beam at the sample based on the effect of a laser induced plasma on the electron beam transverse distribution, successfully extending a similar method from keV to MeV electron beams. By pumping a standard copper TEM grid to form the plasma, we gain timing information independent of the sample under study. In experiments discussed here the optical delay to achieve temporal overlap between the pump electron beam and probe laser can be determined with ~1 ps precision. Copyright © 2012 Elsevier B.V. All rights reserved.

Regulation of gonadotropin receptors on cultured porcine Leydig and Sertoli cells: effect of potassium depletion.

PubMed

Bernier, M; Laferrere, B; Jaillard, C; Clerget, M; Saez, J M

1986-06-01

We have examined the role of the NaK-ATPase pump activity on the ligand-induced down-regulation of gonadotropin receptors in cultured porcine Leydig and Sertoli cells. In both cells, inhibition of the NaK pump by ouabain produced a depletion of intracellular K+ levels (ID50, 10(-7) M) after a lag period of about 8 h. In the absence of ligand, the number of FSH receptors in ouabain-treated Sertoli cells was unaffected or slightly reduced, whereas a 2-fold increase in the number of human CG (hCG)/LH receptors with small changes in the binding affinity was observed in Leydig cells treated by ouabain. The effect of ouabain was dose dependent. Differences were also observed in the down-regulation process of gonadotropin receptors in ouabain-treated cells. The hCG-induced receptor loss in Leydig cells was completely reversed by ouabain whereas the drug had no effect on ligand-induced loss of FSH receptors in Sertoli cells. Similar results were observed when the cells were incubated in K+-free medium. Kinetics studies with labeled hCG have shown that ouabain treatment slows down significantly the rate of [125I]iodo-hCG internalization (t 1/2, 18 h; control cells, t 1/2, 6 h), but had no effect on the degradation of internalized hormone. The internalization of receptor-bound [125I]iodo-hCG was also reduced when Leydig cells were incubated in K+-free medium, but was restored when this medium was supplemented with rubidium. The influence of the NaK pump on the receptor regulation of a ligand common to both types of cells, such as epidermal growth factor, was studied under the same experimental conditions. Neither ouabain nor K+-free medium were able to prevent the epidermal growth factor-induced reduction of receptor levels in Leydig and Sertoli cells. Thus, it appears that modulation of ligand-induced receptor loss by depletion of cellular K+ levels is not dependent on the cell type, but on the ligand-receptor complex. The data also show a striking difference in the dynamics of gonadotropin-receptor interaction of two structurally related hormones.

Twisting Anderson pseudospins with light: Quench dynamics in terahertz-pumped BCS superconductors

NASA Astrophysics Data System (ADS)

Chou, Yang-Zhi; Liao, Yunxiang; Foster, Matthew S.

2017-03-01

We study the preparation (pump) and the detection (probe) of far-from-equilibrium BCS superconductor dynamics in THz pump-probe experiments. In a recent experiment [R. Matsunaga, Y. I. Hamada, K. Makise, Y. Uzawa, H. Terai, Z. Wang, and R. Shimano, Phys. Rev. Lett. 111, 057002 (2013), 10.1103/PhysRevLett.111.057002], an intense monocycle THz pulse with center frequency ω ≃Δ was injected into a superconductor with BCS gap Δ ; the subsequent postpump evolution was detected via the optical conductivity. It was argued that nonlinear coupling of the pump to the Anderson pseudospins of the superconductor induces coherent dynamics of the Higgs (amplitude) mode Δ (t ) . We validate this picture in a two-dimensional BCS model with a combination of exact numerics and the Lax reduction method, and we compute the nonequilibrium phase diagram as a function of the pump intensity. The main effect of the pump is to scramble the orientations of Anderson pseudospins along the Fermi surface by twisting them in the x y plane. We show that more intense pump pulses can induce a far-from-equilibrium phase of gapless superconductivity ("phase I"), originally predicted in the context of interaction quenches in ultracold atoms. We show that the THz pump method can reach phase I at much lower energy densities than an interaction quench, and we demonstrate that Lax reduction (tied to the integrability of the BCS Hamiltonian) provides a general quantitative tool for computing coherent BCS dynamics. We also calculate the Mattis-Bardeen optical conductivity for the nonequilibrium states discussed here.

46 CFR 61.20-3 - Main and auxiliary machinery and associated equipment, including fluid control systems.

Code of Federal Regulations, 2010 CFR

2010-10-01

... control for the means of stopping machinery driving forced and induced draft fans, fuel oil transfer pumps, fuel oil unit pumps, and fans in the ventilation systems serving machinery and cargo spaces shall be...

Carbon ion pump for removal of carbon dioxide from combustion gas and other gas mixtures

DOEpatents

Aines, Roger D.; Bourcier, William L.

2014-08-19

A novel method and system of separating carbon dioxide from flue gas is introduced. Instead of relying on large temperature or pressure changes to remove carbon dioxide from a solvent used to absorb it from flue gas, the ion pump method, as disclosed herein, dramatically increases the concentration of dissolved carbonate ion in solution. This increases the overlying vapor pressure of carbon dioxide gas, permitting carbon dioxide to be removed from the downstream side of the ion pump as a pure gas. The ion pumping may be obtained from reverse osmosis, electrodialysis, thermal desalination methods, or an ion pump system having an oscillating flow in synchronization with an induced electric field.

Carbon ion pump for removal of carbon dioxide from combustion gas and other gas mixtures

DOEpatents

Aines, Roger D.; Bourcier, William L.

2010-11-09

A novel method and system of separating carbon dioxide from flue gas is introduced. Instead of relying on large temperature or pressure changes to remove carbon dioxide from a solvent used to absorb it from flue gas, the ion pump method, as disclosed herein, dramatically increases the concentration of dissolved carbonate ion in solution. This increases the overlying vapor pressure of carbon dioxide gas, permitting carbon dioxide to be removed from the downstream side of the ion pump as a pure gas. The ion pumping may be obtained from reverse osmosis, electrodialysis, thermal desalination methods, or an ion pump system having an oscillating flow in synchronization with an induced electric field.

Detection of pure inverse spin-Hall effect induced by spin pumping at various excitation

NASA Astrophysics Data System (ADS)

Inoue, H. Y.; Harii, K.; Ando, K.; Sasage, K.; Saitoh, E.

2007-10-01

Electric-field generation due to the inverse spin-Hall effect (ISHE) driven by spin pumping was detected and separated experimentally from the extrinsic magnetogalvanic effects in a Ni81Fe19/Pt film. By applying a sample-cavity configuration in which the extrinsic effects are suppressed, the spin pumping using ferromagnetic resonance gives rise to a symmetric spectral shape in the electromotive force spectrum, indicating that the motive force is due entirely to ISHE. This method allows the quantitative analysis of the ISHE and the spin-pumping effect. The microwave-power dependence of the ISHE amplitude is consistent with the prediction of a direct current-spin-pumping scenario.

Electronic properties of solids excited with intermediate laser power densities

NASA Astrophysics Data System (ADS)

Sirotti, Fausto; Tempo Beamline Team

Intermediate laser power density up to about 100 GW/cm2 is below the surface damage threshold is currently used to induce modification in the physical properties on short time scales. The absorption of a short laser pulse induces non-equilibrium electronic distributions followed by lattice-mediated equilibrium taking place only in the picosecond range. The role of the hot electrons is particularly important in several domains as for example fast magnetization and demagnetization processes, laser induced phase transitions, charge density waves. Angular resolved photoelectron spectroscopy measuring directly energy and momentum of electrons is the most adapted tool to study the electronic excitations at short time scales during and after fast laser excitations. The main technical problem is the space charge created by the pumping laser pulse. I will present angular resolved multiphoton photoemission results obtained with 800 nm laser pulses showing how space charge electrons emitted during fast demagnetization processes can be measured. Unable enter Affiliation: CNRS-SOLEIL Synchrotron L'Orme des Merisiers , Saint Aubin 91192 Gif sur Yvette France.

Increase of economy of torque flow pump with high specific speed

NASA Astrophysics Data System (ADS)

Gusak, A. G.; Krishtop, I. V.; German, V. F.; Baga, V. N.

2017-08-01

Torque flow pumps are widely spread types of energy machines, which are used in majority of modern branches of industry for pumping of dirty media. The main task of researchers of torque flow pumps is increase of such pumps effectiveness for higher feed. Hydraulic losses for torque flow pumps are caused by working process of such pumps and are inevitable. Decrease of losses can be obtained by means of optimization of hydraulic flow part geometry. Modern approach to design of pump outlet introduces new constructive solutions which can increase economy of torque flow pumps. The aim of this research is increase of economy of torque flow pumps by means of application of spatial outlet and investigation of its geometry on pump characteristics. Analytical and numerical methods of liquid flow research for hydraulic flow part of torque flow pump were used in this paper. Moreover, influence of hydraulic flow part geometry of different designs of “Turo” type torque flow pumps outlets on pump characteristics was investigated. Numerical research enabled to study process of energy transfer of torque flow pump and evaluate influence of geometrical dimensions of spatial spiral outlet on its characteristics. Besides numerical research confirmed introduced regularity of peripheral velocity distribution in outlet. Velocity moment distribution in outlet was obtained during implementation of numerical research. Implemented bench tests of torque flow pump prototypes enabled to obtain real characteristics of pump and confirm effectiveness of spatial geometry of outlet application for such pump.

Pump CFD code validation tests

NASA Technical Reports Server (NTRS)

Brozowski, L. A.

1993-01-01

Pump CFD code validation tests were accomplished by obtaining nonintrusive flow characteristic data at key locations in generic current liquid rocket engine turbopump configurations. Data were obtained with a laser two-focus (L2F) velocimeter at scaled design flow. Three components were surveyed: a 1970's-designed impeller, a 1990's-designed impeller, and a four-bladed unshrouded inducer. Two-dimensional velocities were measured upstream and downstream of the two impellers. Three-dimensional velocities were measured upstream, downstream, and within the blade row of the unshrouded inducer.

Inward H+ pump xenorhodopsin: Mechanism and alternative optogenetic approach.

PubMed

Shevchenko, Vitaly; Mager, Thomas; Kovalev, Kirill; Polovinkin, Vitaly; Alekseev, Alexey; Juettner, Josephine; Chizhov, Igor; Bamann, Christian; Vavourakis, Charlotte; Ghai, Rohit; Gushchin, Ivan; Borshchevskiy, Valentin; Rogachev, Andrey; Melnikov, Igor; Popov, Alexander; Balandin, Taras; Rodriguez-Valera, Francisco; Manstein, Dietmar J; Bueldt, Georg; Bamberg, Ernst; Gordeliy, Valentin

2017-09-01

Generation of an electrochemical proton gradient is the first step of cell bioenergetics. In prokaryotes, the gradient is created by outward membrane protein proton pumps. Inward plasma membrane native proton pumps are yet unknown. We describe comprehensive functional studies of the representatives of the yet noncharacterized xenorhodopsins from Nanohaloarchaea family of microbial rhodopsins. They are inward proton pumps as we demonstrate in model membrane systems, Escherichia coli cells, human embryonic kidney cells, neuroblastoma cells, and rat hippocampal neuronal cells. We also solved the structure of a xenorhodopsin from the nanohalosarchaeon Nanosalina ( Ns XeR) and suggest a mechanism of inward proton pumping. We demonstrate that the Ns XeR is a powerful pump, which is able to elicit action potentials in rat hippocampal neuronal cells up to their maximal intrinsic firing frequency. Hence, inwardly directed proton pumps are suitable for light-induced remote control of neurons, and they are an alternative to the well-known cation-selective channelrhodopsins.

CF.sub.4 laser

DOEpatents

Wittig, Curt; Tiee, Joe J.

1979-01-01

A CF.sub.4 laser for producing near 16 .mu.m radiation utilizing a line tunable CO.sub.2 laser as an optical pumping source. The device uses a cryogenically cooled optically pumped cell containing molecular CF.sub.4 gas. An optical resonant cavity formed around the optically pumped cell induces oscillations of near 16 .mu.m radiation from the .nu..sub.2 +.nu..sub.4 .fwdarw..nu..sub.2 transition in the molecular CF.sub.4 gas.

Laser spark distribution and ignition system

DOEpatents

Woodruff, Steven [Morgantown, WV; McIntyre, Dustin L [Morgantown, WV

2008-09-02

A laser spark distribution and ignition system that reduces the high power optical requirements for use in a laser ignition and distribution system allowing for the use of optical fibers for delivering the low peak energy pumping pulses to a laser amplifier or laser oscillator. An optical distributor distributes and delivers optical pumping energy from an optical pumping source to multiple combustion chambers incorporating laser oscillators or laser amplifiers for inducing a laser spark within a combustion chamber. The optical distributor preferably includes a single rotating mirror or lens which deflects the optical pumping energy from the axis of rotation and into a plurality of distinct optical fibers each connected to a respective laser media or amplifier coupled to an associated combustion chamber. The laser spark generators preferably produce a high peak power laser spark, from a single low power pulse. The laser spark distribution and ignition system has application in natural gas fueled reciprocating engines, turbine combustors, explosives and laser induced breakdown spectroscopy diagnostic sensors.

Research on radiation induced laser plasmas

NASA Technical Reports Server (NTRS)

Schneider, R. T.; Rowe, M. J.; Carter, B. D.; Walters, R. A.; Cox, J. D.; Liang, R.; Roxey, T.; Zapata, L.

1979-01-01

The development of high power nuclear pumped lasers is discussed. The excitation mechanism of continuous wave (CW) HeNe nuclear pumped lasers is studied and a CO2 nuclear pumped laser is used to demonstrate the CW output in the order of watts. The assumption that high power densities are only achievable by volume fission fragment sources is used to identify laser gases which are compatible with UF6 by excited states lifetime measurements. The examination of Xe2, XeF, and KrF under nuclear irradiation to determine if they are good candidates for nuclear-pumped lasers is described.

Electromagnetic induction pump for pumping liquid metals and other conductive liquids

DOEpatents

Smither, R.K.

1993-05-11

An electromagnetic induction pump is described in which an electrically conductive liquid is made to flow by means of a force created by interaction of a permanent magnetic field and a DC current. The pump achieves high efficiency through combination of: powerful permanent magnet materials which provide a high strength field that is uniform and constant; steel tubing formed into a coil which is constructed to carry conducting liquids with minimal electrical resistance and heat; and application of a voltage to induce a DC current which continuously produces a force in the direction of the desired flow.

Electromagnetic induction pump for pumping liquid metals and other conductive liquids

DOEpatents

Smither, Robert K.

1993-01-01

An electromagnetic induction pump in which an electrically conductive liquid is made to flow by means of a force created by interaction of a permanent magnetic field and a DC current. The pump achieves high efficiency through combination of: powerful permanent magnet materials which provide a high strength field that is uniform and constant; steel tubing formed into a coil which is constructed to carry conducting liquids with minimal electrical resistance and heat; and application of a voltage to induce a DC current which continuously produces a force in the direction of the desired flow.

Diode-pumped large-aperture Nd:YAG slab amplifier for high energy nanosecond pulse laser

NASA Astrophysics Data System (ADS)

Guo, Guangyan; Chen, Yanzhong; He, Jianguo; Lang, Ye; Lin, Weiran; Tang, Xiongxin; Zhang, Hongbo; Kang, Zhijun; Fan, Zhongwei

2017-10-01

A high gain, low thermal-induced wavefront distortion, laser diode-pumped Nd: YAG slab amplifier is demonstrated with its active media dimensions of 7 mm ×35 mm ×138.2 mm. Under the 200 Hz, 1440 W pulse pumping condition while no seed light to amplify, the thermal induced wavefront aberration of a He-Ne probe passing through the gain meUdium is 0.165 λ@633 nm (RMS). The amplifier shows stable aberration character with two major low-order terms, defocus and 0° astigmatism. The fluorescence distribution, stored energy, and small-signal gain of the amplifier are measured and have a good agreement with the calculated results. In the amplifier, the fluorescence is uniformly distributed and the maximum stored energy of 3.2 J can be achieved with a plane-concave cavity at 200 Hz pump repetition frequency. For a repetition frequency of 200 Hz, 25 μJ injection polarized seed-light and 1440 W pump power, the small signal gain reaches 9.45. The amplifier has been successfully employed in a 200 Hz, 5 J, MOPA system with 1.7 times diffraction limited output.

Involvement of the Efflux Pumps in Chloramphenicol Selected Strains of Burkholderia thailandensis: Proteomic and Mechanistic Evidence

PubMed Central

Biot, Fabrice V.; Valade, Eric; Garnotel, Eric; Chevalier, Jacqueline; Villard, Claude; Thibault, François M.; Vidal, Dominique R.; Pagès, Jean-Marie

2011-01-01

Burkholderia is a bacterial genus comprising several pathogenic species, including two species highly pathogenic for humans, B. pseudomallei and B. mallei. B. thailandensis is a weakly pathogenic species closely related to both B. pseudomallei and B. mallei. It is used as a study model. These bacteria are able to exhibit multiple resistance mechanisms towards various families of antibiotics. By sequentially plating B. thailandensis wild type strains on chloramphenicol we obtained several resistant variants. This chloramphenicol-induced resistance was associated with resistance against structurally unrelated antibiotics including quinolones and tetracyclines. We functionally and proteomically demonstrate that this multidrug resistance phenotype, identified in chloramphenicol-resistant variants, is associated with the overexpression of two different efflux pumps. These efflux pumps are able to expel antibiotics from several families, including chloramphenicol, quinolones, tetracyclines, trimethoprim and some β-lactams, and present a partial susceptibility to efflux pump inhibitors. It is thus possible that Burkholderia species can develop such adaptive resistance mechanisms in response to antibiotic pressure resulting in emergence of multidrug resistant strains. Antibiotics known to easily induce overexpression of these efflux pumps should be used with discernment in the treatment of Burkholderia infections. PMID:21347382

DOE Office of Scientific and Technical Information (OSTI.GOV)

Oloff, L.-P., E-mail: oloff@physik.uni-kiel.de; Hanff, K.; Stange, A.

With the advent of ultrashort-pulsed extreme ultraviolet sources, such as free-electron lasers or high-harmonic-generation (HHG) sources, a new research field for photoelectron spectroscopy has opened up in terms of femtosecond time-resolved pump-probe experiments. The impact of the high peak brilliance of these novel sources on photoemission spectra, so-called vacuum space-charge effects caused by the Coulomb interaction among the photoemitted probe electrons, has been studied extensively. However, possible distortions of the energy and momentum distributions of the probe photoelectrons caused by the low photon energy pump pulse due to the nonlinear emission of electrons have not been studied in detail yet.more » Here, we systematically investigate these pump laser-induced space-charge effects in a HHG-based experiment for the test case of highly oriented pyrolytic graphite. Specifically, we determine how the key parameters of the pump pulse—the excitation density, wavelength, spot size, and emitted electron energy distribution—affect the measured time-dependent energy and momentum distributions of the probe photoelectrons. The results are well reproduced by a simple mean-field model, which could open a path for the correction of pump laser-induced space-charge effects and thus toward probing ultrafast electron dynamics in strongly excited materials.« less

Mean Line Pump Flow Model in Rocket Engine System Simulation

NASA Technical Reports Server (NTRS)

Veres, Joseph P.; Lavelle, Thomas M.

2000-01-01

A mean line pump flow modeling method has been developed to provide a fast capability for modeling turbopumps of rocket engines. Based on this method, a mean line pump flow code PUMPA has been written that can predict the performance of pumps at off-design operating conditions, given the loss of the diffusion system at the design point. The pump code can model axial flow inducers, mixed-flow and centrifugal pumps. The code can model multistage pumps in series. The code features rapid input setup and computer run time, and is an effective analysis and conceptual design tool. The map generation capability of the code provides the map information needed for interfacing with a rocket engine system modeling code. The off-design and multistage modeling capabilities of the code permit parametric design space exploration of candidate pump configurations and provide pump performance data for engine system evaluation. The PUMPA code has been integrated with the Numerical Propulsion System Simulation (NPSS) code and an expander rocket engine system has been simulated. The mean line pump flow code runs as an integral part of the NPSS rocket engine system simulation and provides key pump performance information directly to the system model at all operating conditions.

Magnetization dissipation in the ferromagnetic semiconductor (Ga,Mn)As

NASA Astrophysics Data System (ADS)

Hals, Kjetil M. D.; Brataas, Arne

2011-09-01

We compute the Gilbert damping in (Ga,Mn)As based on the scattering theory of magnetization relaxation. The disorder scattering is included nonperturbatively. In the clean limit, spin pumping from the localized d electrons to the itinerant holes dominates the relaxation processes. In the diffusive regime, the breathing Fermi-surface effect is balanced by the effects of interband scattering, which cause the Gilbert damping constant to saturate at around 0.005. In small samples, the system shape induces a large anisotropy in the Gilbert damping.

CFD analyses for advanced pump design

NASA Technical Reports Server (NTRS)

Dejong, F. J.; Choi, S.-K.; Govindan, T. R.

1994-01-01

As one of the activities of the NASA/MSFC Pump Stage Technology Team, the present effort was focused on using CFD in the design and analysis of high performance rocket engine pumps. Under this effort, a three-dimensional Navier-Stokes code was used for various inducer and impeller flow field calculations. An existing algebraic grid generation procedure was-extended to allow for nonzero blade thickness, splitter blades, and hub/shroud cavities upstream or downstream of the (main) blades. This resulted in a fast, robust inducer/impeller geometry/grid generation package. Problems associated with running a compressible flow code to simulate an incompressible flow were resolved; related aspects of the numerical algorithm (viz., the matrix preconditioning, the artificial dissipation, and the treatment of low Mach number flows) were addressed. As shown by the calculations performed under the present effort, the resulting code, in conjunction with the grid generation package, is an effective tool for the rapid solution of three-dimensional viscous inducer and impeller flows.

Out-of-equilibrium catalysis of chemical reactions by electronic tunnel currents.

PubMed

Dzhioev, Alan A; Kosov, Daniel S; von Oppen, Felix

2013-04-07

We present an escape rate theory for current-induced chemical reactions. We use Keldysh nonequilibrium Green's functions to derive a Langevin equation for the reaction coordinate. Due to the out of equilibrium electronic degrees of freedom, the friction, noise, and effective temperature in the Langevin equation depend locally on the reaction coordinate. As an example, we consider the dissociation of diatomic molecules induced by the electronic current from a scanning tunnelling microscope tip. In the resonant tunnelling regime, the molecular dissociation involves two processes which are intricately interconnected: a modification of the potential energy barrier and heating of the molecule. The decrease of the molecular barrier (i.e., the current induced catalytic reduction of the barrier) accompanied by the appearance of the effective, reaction-coordinate-dependent temperature is an alternative mechanism for current-induced chemical reactions, which is distinctly different from the usual paradigm of pumping vibrational degrees of freedom.

Dissipative rogue waves induced by soliton explosions in an ultrafast fiber laser.

PubMed

Liu, Meng; Luo, Ai-Ping; Xu, Wen-Cheng; Luo, Zhi-Chao

2016-09-01

We reported on the observation of dissipative rogue waves (DRWs) induced by soliton explosions in an ultrafast fiber laser. It was found that the soliton explosions could be obtained in the fiber laser at a critical pump power level. During the process of the soliton explosion, the high-amplitude waves that fulfill the rogue wave criteria could be detected. The appearance of the DRWs was identified by characterizing the intensity statistics of the time-stretched soliton profile based on the dispersive Fourier-transform method. Our findings provide the first experimental demonstration that the DRWs could be observed in the soliton explosion regime and further enhance the understanding of the physical mechanism of optical RW generation.

Cryogenic hydrogen-induced air-liquefaction technologies for combined-cycle propulsion applications

NASA Technical Reports Server (NTRS)

Escher, William J. D.

1992-01-01

Given here is a technical assessment of the realization of cryogenic hydrogen induced air liquefaction technologies in a prospective onboard aerospace vehicle process setting. The technical findings related to the status of air liquefaction technologies are reviewed. Compact lightweight cryogenic heat exchangers, heat exchanger atmospheric constituent fouling alleviation measures, para/ortho-hydrogen shift-conversion catalysts, cryogenic air compressors and liquid air pumps, hydrogen recycling using slush hydrogen as a heat sink, liquid hydrogen/liquid air rocket-type combustion devices, and technically related engine concepts are discussed. Much of the LACE work is related to aerospaceplane propulsion concepts that were developed in the 1960's. Emphasis is placed on the Liquid Air Cycle Engine (LACE).

Fault Detection and Safety in Closed-Loop Artificial Pancreas Systems

PubMed Central

2014-01-01

Continuous subcutaneous insulin infusion pumps and continuous glucose monitors enable individuals with type 1 diabetes to achieve tighter blood glucose control and are critical components in a closed-loop artificial pancreas. Insulin infusion sets can fail and continuous glucose monitor sensor signals can suffer from a variety of anomalies, including signal dropout and pressure-induced sensor attenuations. In addition to hardware-based failures, software and human-induced errors can cause safety-related problems. Techniques for fault detection, safety analyses, and remote monitoring techniques that have been applied in other industries and applications, such as chemical process plants and commercial aircraft, are discussed and placed in the context of a closed-loop artificial pancreas. PMID:25049365

Effect of the self-pumped limiter concept on the tritium fuel cycle

DOE Office of Scientific and Technical Information (OSTI.GOV)

Finn, P.A.; Sze, D.K.; Hassanein, A.

1988-09-01

The self-pumped limiter concept was the impurity control system for the reactor in the Tokamak Power Systems Study (TPSS). The use of a self-pumped limiter had a major impact on the design of the tritium systems of the TPSS fusion reactor. The self-pumped limiter functions by depositing the helium ash under a layer of metal (vanadium). The majority of the hydrogen species are recycled at the plasma edge; a small fraction permeates to the blanket/coolant which was lithium in TPSS. Use of the self-pumped limiter results in the elimination of the plasma processing system. Thus, the blanket tritium processing systemmore » becomes the major tritium system. The main advantages achieved for the tritium systems with a self-pumped limiter are a reduction in the capital cost of tritium processing equipment as well as a reduction in building space, a reduced tritium inventory for processing and for reserve storage, an increase in the inherent safety of the fusion plant and an improvement in economics for a fusion world economy.« less

Gastroesophageal reflux symptoms not responding to proton pump inhibitor: GERD, NERD, NARD, esophageal hypersensitivity or dyspepsia?

PubMed Central

Bashashati, Mohammad; Hejazi, Reza A; Andrews, Christopher N; Storr, Martin A

2014-01-01

Gastroesophageal reflux (GER) is a common gastrointestinal process that can generate symptoms of heartburn and chest pain. Proton pump inhibitors (PPIs) are the gold standard for the treatment of GER; however, a substantial group of GER patients fail to respond to PPIs. In the past, it was believed that acid reflux into the esophagus causes all, or at least the majority, of symptoms attributed to GER, with both erosive esophagitis and nonerosive outcomes. However, with modern testing techniques it has been shown that, in addition to acid reflux, the reflux of nonacid gastric and duodenal contents into the esophagus may also induce GER symptoms. It remains unknown how weakly acidic or alkaline refluxate with a pH similar to a normal diet induces GER symptoms. Esophageal hypersensitivity or functional dyspepsia with superimposed heartburn may be other mechanisms of symptom generation, often completely unrelated to GER. Detailed studies investigating the pathophysiology of esophageal hypersensitivity are not conclusive, and definitions of the various disease states may overlap and are often confusing. The authors aim to clarify the pathophysiology, definition, diagnostic techniques and medical treatment of patients with heartburn symptoms who fail PPI therapy. PMID:24719900

DOE Office of Scientific and Technical Information (OSTI.GOV)

Picón, A.; Lehmann, C. S.; Bostedt, C.

New capabilities at X-ray free-electron laser facilities allow the generation of two-colour femtosecond X-ray pulses, opening the possibility of performing ultrafast studies of X-ray-induced phenomena. Specifically, the experimental realization of hetero-site-specific X-ray-pump/X-ray-probe spectroscopy is of special interest, in which an X-ray pump pulse is absorbed at one site within a molecule and an X-ray probe pulse follows the X-ray-induced dynamics at another site within the same molecule. In this paper, we show experimental evidence of a hetero-site pump-probe signal. By using two-colour 10-fs X-ray pulses, we are able to observe the femtosecond time dependence for the formation of F ionsmore » during the fragmentation of XeF 2 molecules following X-ray absorption at the Xe site.« less

Laser-induced vibration of a thin soap film.

PubMed

Emile, Olivier; Emile, Janine

2014-09-21

We report on the vibration of a thin soap film based on the optical radiation pressure force. The modulated low power laser induces a counter gravity flow in a vertical free-standing draining film. The thickness of the soap film is then higher in the upper region than in the lower region of the film. Moreover, the lifetime of the film is dramatically increased by a factor of 2. Since the laser beam only acts mechanically on the film interfaces, such a film can be employed in an optofluidic diaphragm pump, the interfaces behaving like a vibrating membrane and the liquid in-between being the fluid to be pumped. Such a pump could then be used in delicate micro-equipment, in chips where temperature variations are detrimental and even in biological systems.

A simple preparative free-flow electrophoresis joined with gratis gravity: I. Gas cushion injector and self-balance collector instead of multiple channel pump.

PubMed

Chen, Su; Palmer, James F; Zhang, Wei; Shao, Jing; Li, Si; Fan, Liu-Yin; Sun, Ren; Dong, Yu-Chao; Cao, Cheng-Xi

2009-06-01

This paper describes a novel free-flow electrophoresis (FFE), which is joined with gratis gravity, gas cushion injector (GCI) and self-balance collector instead of multiple channel pump, for the purpose of preparative purification. The FFE was evaluated by systemic experiments. The results manifest that (i) even though one-channel peristaltic pump is used for the driving of background buffer, there is still stable flow in the FFE chamber; (ii) the stable flow is induced by the gravity-induced pressure due to the difference of buffer surfaces in the GCI and self-balance collector; (iii) the pulse flow of background buffer induced by the peristaltic pump is greatly reduced by the GCI with good compressibility of included air; (iv) the FFE can be well used for zone electrophoretic separation of amino acids; (v) up to 20 inlets simultaneous sample injection and up to five to tenfold condensation of amino acid can be achieved by combining the FFE device with the method of moving reaction boundary. To the best of authors' knowledge, FFE has not been used for such separation and condensation of amino acids. The relevant results achieved in the paper have evident significance for the development of preparative FFE.

Parametric presentation of dielectric function of laser pumped wide-zone semiconductor material: Does this function satisfy the Kramers-Kronig relations?

NASA Astrophysics Data System (ADS)

Zimnyakov, D. A.; Yuvchenko, S. A.; Volchkov, S. S.; Samorodina, T. V.

2018-04-01

Dielectric function of wide-zone semiconductor nanoparticles (titanium dioxide) was studied under the condition of laser pumping at various wavelengths. A closed-aperture z-scan method with simultaneous measurements of the right-anglescattered intensity was used to retrieve the real and imaginary parts of dielectric function in the dependence on the pump intensity. It was found that the efficiency of dielectric function modulation by pumping light strongly depends on detuning of the wavelength of pumping light with respect to the fundamental absorption band of nanoparticles. The ColeCole diagrammatic technique was applied for interpretation of the pump-induced changes of the dielectric function in the optical range. Applicability of the Kramers-Kronig relations for description of the observed behavior of the dielectric function is discussed.

40 CFR 455.21 - Specialized definitions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... pollution control blowdown, steam jet blowdown, vacuum pump water, pump seal water, safety equipment.../process laboratory quality control wastewater. Notwithstanding any other regulation, process wastewater...

40 CFR 455.21 - Specialized definitions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... pollution control blowdown, steam jet blowdown, vacuum pump water, pump seal water, safety equipment.../process laboratory quality control wastewater. Notwithstanding any other regulation, process wastewater...

40 CFR 455.21 - Specialized definitions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... pollution control blowdown, steam jet blowdown, vacuum pump water, pump seal water, safety equipment.../process laboratory quality control wastewater. Notwithstanding any other regulation, process wastewater...

Turbopump options for nuclear thermal rockets

NASA Astrophysics Data System (ADS)

Bissell, W. R.; Gunn, S. V.

1992-07-01

Several turbopump options for delivering liquid nitrogen to nuclear thermal rocket (NTR) engines were evaluated and compared. Axial and centrifugal flow pumps were optimized, with and without boost pumps, utilizing current design criteria within the latest turbopump technology limits. Two possible NTR design points were used, a modest pump pressure rise of 1,743 psia and a relatively higher pump pressure rise of 4,480 psia. Both engines utilized the expander cycle to maximize engine performance for the long duration mission. Pump suction performance was evaluated. Turbopumps with conventional cavitating inducers were compared with zero NPSH (saturated liquid in the tanks) pumps over a range of tank saturation pressures, with and without boost pumps. Results indicate that zero NSPH pumps at high tank vapor pressures, 60 psia, are very similar to those with the finite NPSHs. At low vapor pressures efficiencies fall and turbine pressure ratios increase leading to decreased engine chamber pressures and or increased pump pressure discharges and attendant high-pressure component weights. It may be concluded that zero tank NSPH capabilities can be obtained with little penalty to the engine systems but boost pumps are needed if tank vapor pressure drops below 30 psia. Axial pumps have slight advantages in weight and chamber pressure capability while centrifugal pumps have a greater operating range.

Third harmonic from air breakdown plasma induced by nanosecond laser pulses

NASA Astrophysics Data System (ADS)

Stafe, M.; Negutu, C.; Puscas, N. N.

2018-06-01

Harmonic generation is a nonlinear optical effect consisting in frequency up-conversion of intense laser radiation when phase-matching conditions are fulfilled. Here, we study the mechanisms involved in the third harmonic (TH) generation process, the conversion efficiency, and the properties of TH radiation generated in air by focusing infrared linearly polarized nanosecond laser pulses at intensities of the order of TW/cm2. By analyzing the emission from the air breakdown plasma, we demonstrate that filamentary breakdown plasma containing molecular nitrogen ions acts as an optical nonlinear medium enabling generation of TH radiation in the axial direction. The data reveal important properties of the TH radiation: maximum conversion efficiency of 0.04%, sinc2 dependence of the TH intensity on the square root of the pump intensity, and three times smaller divergence and pulse duration of TH as compared to the pump radiation.

Dynamics of charge clouds ejected from laser-induced warm dense gold nanofilms

DOE PAGES

Zhou, Jun; Li, Junjie; Correa, Alfredo A.; ...

2014-10-24

We report the first systematic study of the ejected charge dynamics surrounding laser-produced 30-nm warm dense gold films using single-shot femtosecond electron shadow imaging and deflectometry. The results reveal a two-step dynamical process of the ejected electrons under the high pump fluence conditions: an initial emission and accumulation of a large amount of electrons near the pumped surface region followed by the formation of hemispherical clouds of electrons on both sides of the film, which are escaping into the vacuum at a nearly isotropic and constant velocity with an unusually high kinetic energy of more than 300 eV. We alsomore » developed a model of the escaping charge distribution that not only reproduces the main features of the observed charge expansion dynamics but also allows us to extract the number of ejected electrons remaining in the cloud.« less

Dynamics of charge clouds ejected from laser-induced warm dense gold nanofilms

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhou, Jun; Li, Junjie; Correa, Alfredo A.

We report the first systematic study of the ejected charge dynamics surrounding laser-produced 30-nm warm dense gold films using single-shot femtosecond electron shadow imaging and deflectometry. The results reveal a two-step dynamical process of the ejected electrons under the high pump fluence conditions: an initial emission and accumulation of a large amount of electrons near the pumped surface region followed by the formation of hemispherical clouds of electrons on both sides of the film, which are escaping into the vacuum at a nearly isotropic and constant velocity with an unusually high kinetic energy of more than 300 eV. We alsomore » developed a model of the escaping charge distribution that not only reproduces the main features of the observed charge expansion dynamics but also allows us to extract the number of ejected electrons remaining in the cloud.« less

Electronic and Vibrational Coherence in Charge-Transfer Reactions

NASA Astrophysics Data System (ADS)

Scherer, Norbert

1996-03-01

The ultrafast dynamics associated with optically-induced intervalence charge-transfer reactions in solution and protein environments are reported. These studies include the Fe^(II)-Fe^(III) MMCT complex Prussian blue and the mixed valence dimer (CN)_5Ru^(II)CNRuRu^(III)(NH_3)_5. The protein systems include blue copper proteins and the bacterial photosynthetic reaction center. The experimental approaches include photon echo, wavelength-resolved pump-probe and anisotropy measurements performed with 12-16fs duration optical pulses. Complicated time-domain waveforms reflect the several different p[rocesses and time scales for relaxation of coherences (both electronic and vibrational) and populations within these systems. The photon echo and anisotropy results probe electronic coherence and dephasing prior to back electron transfer. Wavelength-resolved pump-probe results reveal vibrational modes coupled to the CT-coordinate as well as formation of new product states or vibrational cooling in the ground state following back electron transfer.

Comparing laser induced plasmas formed in diode and excimer pumped alkali lasers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Markosyan, Aram H.

Here, lasing on the D 1 transition (6 2P 1/2 → 6 2S 1/2) of cesium can be reached in both diode and excimer pumped alkali lasers. The first uses D 2 transition (6 2S 1/2 → 6 2P 3/2) for pumping, whereas the second is pumped by photoexcitation of ground state Cs-Ar collisional pairs and subsequent dissociation of diatomic, electronically-excited CsAr molecules (excimers). Despite lasing on the same D 1 transition, differences in pumping schemes enables chemical pathways and characteristic timescales unique for each system. We investigate unavoidable plasma formation during operation of both systems side by side inmore » Ar/C 2H 6/Cs.« less

Comparing laser induced plasmas formed in diode and excimer pumped alkali lasers

DOE PAGES

Markosyan, Aram H.

2018-01-05

Here, lasing on the D 1 transition (6 2P 1/2 → 6 2S 1/2) of cesium can be reached in both diode and excimer pumped alkali lasers. The first uses D 2 transition (6 2S 1/2 → 6 2P 3/2) for pumping, whereas the second is pumped by photoexcitation of ground state Cs-Ar collisional pairs and subsequent dissociation of diatomic, electronically-excited CsAr molecules (excimers). Despite lasing on the same D 1 transition, differences in pumping schemes enables chemical pathways and characteristic timescales unique for each system. We investigate unavoidable plasma formation during operation of both systems side by side inmore » Ar/C 2H 6/Cs.« less

Comparing laser induced plasmas formed in diode and excimer pumped alkali lasers.

PubMed

Markosyan, Aram H

2018-01-08

Lasing on the D 1 transition (6 2 P 1/2 → 6 2 S 1/2 ) of cesium can be reached in both diode and excimer pumped alkali lasers. The first uses D 2 transition (6 2 S 1/2 → 6 2 P 3/2 ) for pumping, whereas the second is pumped by photoexcitation of ground state Cs-Ar collisional pairs and subsequent dissociation of diatomic, electronically-excited CsAr molecules (excimers). Despite lasing on the same D 1 transition, differences in pumping schemes enables chemical pathways and characteristic timescales unique for each system. We investigate unavoidable plasma formation during operation of both systems side by side in Ar/C 2 H 6 /Cs.

Wind-induced upwelling in the Kerguelen Plateau region

NASA Astrophysics Data System (ADS)

Gille, S. T.; Carranza, M. M.; Cambra, R.

2014-11-01

In contrast to most of the Southern Ocean, the Kerguelen Plateau supports an unusually strong spring chlorophyll (Chl a) bloom, likely because the euphotic zone in the region is supplied with higher iron concentrations. This study uses satellite wind, sea surface temperature (SST), and ocean color data to explore the impact of wind-driven processes on upwelling of cold (presumably iron-rich) water to the euphotic zone. Results show that, in the Kerguelen region, cold SSTs correlate with high wind speeds, implying that wind-mixing leads to enhanced vertical mixing. Cold SSTs also correlate with negative wind-stress curl, implying that Ekman pumping can further enhance upwelling. In the moderate to high eddy kinetic energy (EKE) regions surrounding Kerguelen, we find evidence of coupling between winds and SST gradients associated with mesoscale eddies, which can locally modulate the wind-stress curl. This coupling introduces persistent wind-stress curl patterns and Ekman pumping around these long-lived eddies, which may modulate the evolution of Chl a in the downstream plume far offshore. Close to the plateau, this eddy coupling breaks down. Kerguelen has a significant wind shadow on its downwind side, which changes position depending on the prevailing wind and which generates a wind-stress curl dipole that shifts location depending on wind direction. This leads to locally enhanced Ekman pumping for a few hundred kilometers downstream from the Kerguelen Plateau; Chl a values tend to be more elevated in places where wind-stress curl induces Ekman upwelling than in locations of downwelling, although the estimated upwelling rates are too small for this relationship to derive from direct effects on upward iron supply, and thus other processes, which remain to be determined, must also be involved in the establishment of these correlations. During the October and November (2011) KErguelen Ocean and Plateau compared Study (KEOPS-2) field program, wind conditions were fairly typical for the region, with enhanced Ekman upwelling expected to the north of the Kerguelen Islands.

Pump-probe study of the formation of rubidium molecules by ultrafast photoassociation of ultracold atoms

NASA Astrophysics Data System (ADS)

McCabe, David J.; England, Duncan G.; Martay, Hugo E. L.; Friedman, Melissa E.; Petrovic, Jovana; Dimova, Emiliya; Chatel, Béatrice; Walmsley, Ian A.

2009-09-01

An experimental pump-probe study of the photoassociative creation of translationally ultracold rubidium molecules is presented together with numerical simulations of the process. The formation of loosely bound excited-state dimers is observed as a first step toward a fully coherent pump-dump approach to the stabilization of Rb2 into its lowest ground vibrational states. The population that contributes to the pump-probe process is characterized and found to be distinct from a background population of preassociated molecules.

Is back-electron transfer process in Betaine-30 coherent?

NASA Astrophysics Data System (ADS)

Rafiq, Shahnawaz; Scholes, Gregory D.

2017-09-01

The possible role of coherent vibrational motion in ultrafast photo-induced electron transfer remains unclear despite considerable experimental and theoretical advances. We revisited this problem by tracking the back-electron transfer (bET) process in Betaine-30 with broadband pump-probe spectroscopy. Dephasing time constant of certain high-frequency vibrations as a function of solvent shows a trend similar to the ET rates. In the purview of Bixon-Jortner model, high-frequency quantum vibrations bridge the reactant-product energy gap by providing activationless vibronic channels. Such interaction reduces the effective coupling significantly and thereby the coherence effects are eliminated due to energy gap fluctuations, making the back-electron transfer incoherent.

Tunable Q-factor silicon microring resonators for ultra-low power parametric processes.

PubMed

Strain, Michael J; Lacava, Cosimo; Meriggi, Laura; Cristiani, Ilaria; Sorel, Marc

2015-04-01

A compact silicon ring resonator is demonstrated that allows simple electrical tuning of the ring coupling coefficient and Q-factor and therefore the resonant enhancement of on-chip nonlinear optical processes. Fabrication-induced variation in designed coupling fraction, crucial in the resonator performance, can be overcome using this post-fabrication trimming technique. Tuning of the microring resonator across the critical coupling point is demonstrated, exhibiting a Q-factor tunable between 9000 and 96,000. Consequently, resonantly enhanced four-wave mixing shows tunable efficiency between -40 and -16.3  dB at an ultra-low on-chip pump power of 0.7 mW.

The Causes and Prevention Measures of Stuck Pump Phenomenon of Rod-pumped Well in CBM Field

NASA Astrophysics Data System (ADS)

Yonggui, Mei

2018-02-01

In the process of CBM field exploitation, in order to realize the drainage equipment to work continuous stably, the article pays attention to study and solve the stuck pump problem, and aim of reducing reservoir damage and lowing production costs. Through coal particles stuck pump experiment and sediment composition analysis, we find out five primary cause of stuck pump phenomenon: sand from coal seam, sediment from ground, iron corrosion, iron scrap caused by eccentric wear, coal cake. According to stuck pump mechanism, the article puts forward 8 measures to prevent stuck pump phenomenon, and the measures are focused on technology optimization, operation management and drainage process control. After 7 years production practice, the yearly stuck pump rate has dropped from 8.9% to 1.2%, and the pump inspection period has prolonged 2 times. The experiment result shows that pure coal particles cannot cause stuck pump, but sand, scrap iron, and iron corrosion are the primary cause of stuck pump. The article study and design the new pipe string structure that the bottom of the pipe string is open. This kind of pipe string applied the sedimentation terminal velocity theory to solve the stuck pump phenomenon, and it can be widely used in CBM drainage development.

Prevention of Insulin-Induced Hypoglycemia in Type 1 Diabetes with Predictive Low Glucose Management System.

PubMed

Abraham, Mary B; de Bock, Martin; Paramalingam, Nirubasini; O'Grady, Michael J; Ly, Trang T; George, Carly; Roy, Anirban; Spital, Glenn; Karula, Sophy; Heels, Kristine; Gebert, Rebecca; Fairchild, Jan M; King, Bruce R; Ambler, Geoffrey R; Cameron, Fergus; Davis, Elizabeth A; Jones, Timothy W

2016-07-01

Sensor-augmented pump therapy (SAPT) with algorithms to predict impending low blood glucose and suspend insulin delivery has the potential to reduce hypoglycemia exposure. The aim of this study was to determine whether predictive low glucose management (PLGM) system is effective in preventing insulin-induced hypoglycemia in controlled experiments. Two protocols were used to induce hypoglycemia in an in-clinic environment. (A) Insulin bolus: Insulin was administered as a manual bolus through the pump. (B) Increased basal insulin: Hypoglycemia was induced by increasing basal rates overnight to 180%. For both protocols, participants were randomized and studied on 2 separate days; a control day with SAPT alone and an intervention day with SAPT and PLGM activated. The predictive algorithm was programmed to suspend basal insulin infusion when sensor glucose was predicted to be <80 mg/dL in 30 min. The primary outcome was the requirement for hypoglycemia treatment (symptomatic hypoglycemia or plasma glucose <50 mg/dL) and was compared in both control and intervention arms. With insulin bolus, 24/28 participants required hypoglycemia treatment with SAPT alone compared to 5/28 participants when PLGM was activated (P ≤ 0.001). With increased basal rates, all the eight SAPT-alone participants required treatment for hypoglycemia compared to only one with SAPT and PLGM. There was no post pump-suspend hyperglycemia with insulin bolus (P = 0.4) or increased basal rates (P = 0.69) in participants with 2-h pump suspension on intervention days. SAPT with PLGM reduced the requirement for hypoglycemia treatment following insulin-induced hypoglycemia in an in-clinic setting.

Table-top two-color soft X-ray laser by means of Ni-like plasmas

NASA Astrophysics Data System (ADS)

Masoudnia, Leili; Ruiz-Lopez, Mabel; Bleiner, Davide

2016-04-01

Laser-produced Ni-like plasmas are known as active media for extreme ultraviolet lasing, with the flexibility to two-color lasing. Two-color laser generation is very complex at accelerator facilities. In this work, plasma lasing at the 3d94d1(J = 0) → 3d94p1(J = 1) (collisional-pumping process) and the 3d94f1(J = 1) → 3d94d1(J = 1) (photo-pumping process) transitions is studied experimentally and computationally. Several key characteristics of collisional- and photo-pumping laser, such as divergence, pointing stability, and intensity have been investigated. The measurements showed different pulse characteristics for the two lasing processes affected by plasma inhomogeneity in temperature and density. Analytical expressions of these characteristics for both collisional- and photo-pumping are derived. It is found that the plasma that maximizes the photo-pumping lasing is 20% hotter and 70% denser than the plasma that optimizes the collisional-pumping lasing. The gain of collisional pumping is ≈4 times higher than the gain for the photo-pumping. The gain lifetime is a factor of ≈5.2 larger for the monopole-pumping. Similarly, the gain thickness is a factor of ≈1.8 larger. It is also found that the gain build-up time for collisional- and photo-pumping is 0.7 ps and 0.9 ps, respectively, whereas the build-up length-scale is 11.5 μm and 6.3 μm, respectively.

Observation of direct infrared multiphoton pumping of the triplet manifold of biacetyl

NASA Astrophysics Data System (ADS)

Tsao, Jeffrey Y.; Black, Jerry G.; Yablonovitch, Eli; Burak, Itamar

1980-09-01

Direct collisionless multiphoton (MP) excitation of the triplet vibronic manifold of biacetyl is reported. Following a dye laser pulse which prepares some of the biacetyl molecules in the triplet metastable state, the system is irradiated by an intense 20 ns 9.6μ CO2 pulse. The CO2 radiation induces fast quenching of the phosphorescence emission from the 3Au excited molecules. It also induces an emission signal in the fluorescence spectral region of biacetyl. This signal is related to an inverse electronic relaxation (IER) from excited triplet vibronic levels into isoenergetic singlet 1Au vibronic levels. Analysis of the induced luminescence signals provides information on the collisionless MP prompted vibrational distribution. Excitation with 10.6μ CO2 pulses leads to the simultaneous MP pumping of both the ground and triplet manifolds. The generation of blue emission signals in this experiment bears a close resemblance to recent observations of prompt visible emission due to MP pumping of ground state molecules. General expressions for the emission intensities are derived with special emphasis on the specific features of MP vibrational distributions. The detectability of MP induced emission signals is discussed.

Enhancement of survival and electricity production in an engineered bacterium by light-driven proton pumping.

PubMed

Johnson, Ethan T; Baron, Daniel B; Naranjo, Belén; Bond, Daniel R; Schmidt-Dannert, Claudia; Gralnick, Jeffrey A

2010-07-01

Microorganisms can use complex photosystems or light-dependent proton pumps to generate membrane potential and/or reduce electron carriers to support growth. The discovery that proteorhodopsin is a light-dependent proton pump that can be expressed readily in recombinant bacteria enables development of new strategies to probe microbial physiology and to engineer microbes with new light-driven properties. Here, we describe functional expression of proteorhodopsin and light-induced changes in membrane potential in the bacterium Shewanella oneidensis strain MR-1. We report that there were significant increases in electrical current generation during illumination of electrochemical chambers containing S. oneidensis expressing proteorhodopsin. We present evidence that an engineered strain is able to consume lactate at an increased rate when it is illuminated, which is consistent with the hypothesis that proteorhodopsin activity enhances lactate uptake by increasing the proton motive force. Our results demonstrate that there is coupling of a light-driven process to electricity generation in a nonphotosynthetic engineered bacterium. Expression of proteorhodopsin also preserved the viability of the bacterium under nutrient-limited conditions, providing evidence that fulfillment of basic energy needs of organisms may explain the widespread distribution of proteorhodopsin in marine environments.

Characterization of laser damage performance of fused silica using photothermal absorption technique

NASA Astrophysics Data System (ADS)

Wan, Wen; Shi, Feng; Dai, Yifan; Peng, Xiaoqiang

2017-06-01

The subsurface damage and metal impurities have been the main laser damage precursors of fused silica while subjected to high power laser irradiation. Light field enhancement and thermal absorption were used to explain the appearance of damage pits while the laser energy is far smaller than the energy that can reach the intrinsic threshold of fused silica. For fused silica optics manufactured by magnetorheological finishing or advanced mitigation process, no scratch-related damage site occurs can be found on the surface. In this work, we implemented a photothermal absorption technique based on thermal lens method to characterize the subsurface defects of fused silica optics. The pump beam is CW 532 nm wavelength laser. The probe beam is a He-Ne laser. They are collinear and focused through the same objective. When pump beam pass through the sample, optical absorption induces the local temperature rise. The lowest absorptance that we can detect is about the order of magnitude of 0.01 ppm. When pump beam pass through the sample, optical absorption induces the local temperature rise. The photothermal absorption value of fused silica samples range from 0.5 to 10 ppm. The damage densities of the samples were plotted. The damage threshold of samples at 8J/cm2 were gived to show laser damage performance of fused silica.The results show that there is a strong correlation between the thermal absorption and laser damage density. The photothermal absorption technique can be used to predict and evaluate the laser damage performance of fused silica optics.

Pump-induced phase aberrations in Yb3+-doped materials(Conference Presentation)

NASA Astrophysics Data System (ADS)

Keppler, Sebastian; Tamer, Issa; Hornung, Marco; Körner, Jörg; Liebetrau, Hartmut; Hein, Joachim; Kaluza, Malte C.

2017-05-01

Optical pumping of laser materials is an effective way to create a population inversion necessary for laser operation. However, a fraction of the pump energy is always transfered as heat into the laser material, which is mainly caused by the quantum defect. For Yb3+-doped materials, the small energy difference between the pump level and the laser level and the pumping with narrowband high-power laser diodes result in a quantum defect of approx. 9%, which is significantly lower compared to other dopants e.g. Ti3+ (33%) or Nd3+ (24%). Due to the low heat introduction, high optical-to-optical efficiency and high repetition rate laser systems based on diode-pumping are well-suited for a number of applications. Here, however, laser beam quality is of crucial importance. Phase distortions and beam profile modulations can lead to optical damages as well as a significant reduction of the focal spot intensity. Pump-induced phase aberrations are the main cause for phase distortions of the amplified laser beam. The heat transferred to the material causes a change of the refractive index (dn/dT), thermal expansion and stress within the laser material, eventually leading to spatial phase aberrations (also called `thermal lens'). However, the spatially dependent distribution of the population inversion itself also leads to spatial phase aberrations. Since electron excitation directly leads to a change in the charge distribution of the laser active ions, the dynamic response of the material to external fields changes. These electronic phase aberrations (also called `population lens') are described by a change in the polarizability of the material. Due to the low quantum defect of Yb3+-doped materials, this effect becomes more important. We show the first comprehensive spatio-temporal characterization of the pump-induced phase aberration including both effects. A high-resolution interference measurement was carried out with time steps of 50µs for times during the pump period and the cooling period between subsequent pump pulses. We found that both phase effects significantly contribute to the overall phase distortions. Since the temporal characteristic of the electronic phase depends on the fluorescence lifetime and the thermal phase on the thermal diffusivity, both phase effects could be distinguished by their different lifetimes. The measurements were carried out for Yb:YAG, Yb:CaF2 and Yb:glass, and are in excellent agreement to our detailed, COMSOL-based, spatio-temporal phase simulations. Since Yb:CaF2 and Yb:glass provide a negative dn/dT, the electronic phase change becomes even more important and, in case of Yb:CaF2, almost completely compensates the thermal phase imprint of a pump pulse during the time frame of laser pulse amplification.

Pump/Probe Angular Dependence of Hanle Electromagnetically Induced Transparency

NASA Astrophysics Data System (ADS)

Jackson, Richard; Campbell, Kaleb; Crescimanno, Michael; Bali, Samir

2015-05-01

We investigate the dependence of Hanle Electromagnetically Induced Transparency (EIT) on angular separation between pump and probe field propagation directions in room-temperature Rb vapor. We observe the FWHM of the probe transmission spectrum and the amplitude of the EIT signal while varying the angular separation from 0 to 1 milliradian. Following the work of Ref., we examine potential applications in information storage and retrieval. We are grateful to Miami University for their generous financial support, and to the Miami University Instrumentation lab for their invaluable contributions.

A Novel Behavior of Pump Power in the Instability Induced Supercontinuum Generation of Saturable Nonlinear Media

NASA Astrophysics Data System (ADS)

Nithyanandan, K.; Porsezian, K.

2015-04-01

We investigate the modulational instability (MI) induced Supercontinuum generation (SCG) in exponential saturable nonlinearity. The pump power (P) is observed to behave in a unique way such that unlike the conventional Kerr case, the effective nonlinearity of saturable nonlinear system does not monotonously increases with an increase in power. The supercontinuum is observed at the shortest distance of propagation at power equal to the saturation power (Ps), whereas for all combinations of powers (P < Ps or P > Ps) spectral broadening occurs at longer distance.

Study on Operation Optimization of Pumping Station's 24 Hours Operation under Influences of Tides and Peak-Valley Electricity Prices

NASA Astrophysics Data System (ADS)

Yi, Gong; Jilin, Cheng; Lihua, Zhang; Rentian, Zhang

2010-06-01

According to different processes of tides and peak-valley electricity prices, this paper determines the optimal start up time in pumping station's 24 hours operation between the rating state and adjusting blade angle state respectively based on the optimization objective function and optimization model for single-unit pump's 24 hours operation taking JiangDu No.4 Pumping Station for example. In the meantime, this paper proposes the following regularities between optimal start up time of pumping station and the process of tides and peak-valley electricity prices each day within a month: (1) In the rating and adjusting blade angle state, the optimal start up time in pumping station's 24 hours operation which depends on the tide generation at the same day varies with the process of tides. There are mainly two kinds of optimal start up time which include the time at tide generation and 12 hours after it. (2) In the rating state, the optimal start up time on each day in a month exhibits a rule of symmetry from 29 to 28 of next month in the lunar calendar. The time of tide generation usually exists in the period of peak electricity price or the valley one. The higher electricity price corresponds to the higher minimum cost of water pumping at unit, which means that the minimum cost of water pumping at unit depends on the peak-valley electricity price at the time of tide generation on the same day. (3) In the adjusting blade angle state, the minimum cost of water pumping at unit in pumping station's 24 hour operation depends on the process of peak-valley electricity prices. And in the adjusting blade angle state, 4.85%˜5.37% of the minimum cost of water pumping at unit will be saved than that of in the rating state.

Review and Assessment of Commercial Vendors/Options for Feeding and Pumping Biomass Slurries for Hydrothermal Liquefaction

DOE Office of Scientific and Technical Information (OSTI.GOV)

Berglin, Eric J.; Enderlin, Carl W.; Schmidt, Andrew J.

2012-11-01

The National Advanced Biofuels Consortium is working to develop improved methods for producing high-value hydrocarbon fuels. The development of one such method, the hydrothermal liquefaction (HTL) process, is being led by the Pacific Northwest National Laboratory (PNNL). The HTL process uses a wet biomass slurry at elevated temperatures (i.e., 300 to 360°C [570 to 680°F]) and pressures above the vapor pressure of water (i.e., 15 to 20 MPa [2200 to 3000 psi] at these temperatures) to facilitate a condensed-phase reaction medium. The process has been successfully tested at bench-scale and development and testing at a larger scale is required tomore » prove the viability of the process at production levels. Near-term development plans include a pilot-scale system on the order of 0.5 to 40 gpm, followed by a larger production-scale system on the order of 2000 dry metric tons per day (DMTPD). A significant challenge to the scale-up of the HTL process is feeding a highly viscous fibrous biomass wood/corn stover feedstock into a pump system that provides the required 3000 psi of pressure for downstream processing. In October 2011, PNNL began investigating commercial feed and pumping options that would meet these HTL process requirements. Initial efforts focused on generating a HTL feed and pump specification and then providing the specification to prospective vendors to determine the suitability of their pumps for the pilot-scale and production-scale plants. Six vendors were identified that could provide viable equipment to meet HTL feed and/or pump needs. Those six vendors provided options consisting three types of positive displacement pumps (i.e., diaphragm, piston, and lobe pumps). Vendors provided capabilities and equipment related to HTL application. This information was collected, assessed, and summarized and is provided as appendices to this report.« less

Hydration induced material transfer in membranes of osmotic pump tablets measured by synchrotron radiation based FTIR.

PubMed

Wu, Li; Yin, Xianzhen; Guo, Zhen; Tong, Yajun; Feng, Jing; York, Peter; Xiao, Tiqiao; Chen, Min; Gu, Jingkai; Zhang, Jiwen

2016-03-10

Osmotic pump tablets are reliable oral controlled drug delivery systems based on their semipermeable membrane coating. This research used synchrotron radiation-based Fourier transform infrared (SR-FTIR) microspectroscopy and imaging to investigate the hydration induced material transfer in the membranes of osmotic pump tablets. SR-FTIR was applied to record and map the chemical information of a micro-region of the membranes, composed of cellulose acetate (CA, as the water insoluble matrix) and polyethylene glycol (PEG, as the soluble pore forming agent and plasticizing agent). The microstructure and chemical change of membranes hydrated for 0, 5, 10 and 30min were measured using SR-FTIR, combined with scanning electronic microscopy and atom force microscopy. The SR-FTIR microspectroscopy results indicated that there was a major change at the absorption range of 2700-3100cm(-1) in the membranes after different periods of hydration time. The absorption bands at 2870-2880cm(-1) and 2950-2960cm(-1) were assigned to represent CA and PEG, respectively. The chemical group signal distribution illustrated by the ratio of PEG to CA demonstrated that the trigger of drug release in the preliminary stage was due to the rapid transfer of PEG into liquid medium with a sharp decrease of PEG in the membranes. The SR-FTIR mapping results have demonstrated the hydration induced material transfer in the membranes of osmotic pump tablets and enabled reassessment of the drug release mechanism of membrane controlled osmotic pump systems. Copyright © 2016 Elsevier B.V. All rights reserved.

The Control of Welding Deformation of the Three-Section Arm of Placing Boom of HB48B Pump Truck

NASA Astrophysics Data System (ADS)

Wang, Zhi-ling

2018-02-01

The concrete pump truck is the construction equipment of conveying concrete with self contained base plate and distributing boom. It integrates the pump transport mechanism of the concrete pump, and the hydraulic roll-folding type distributing boom used to distribute materials, and the supporting mechanism into the automobile chassis, and it is the concrete conveying equipment with high efficient and the functions of driving, pumping, and distributing materials. The placing boom of the concrete pump truck is the main force member in the pump parts with bearing great pressure, and its stress condition is complex. Taking the HB48B placing boom as an example, this paper analyzes and studies the deformation produced by placing boom of pump truck, and then obtains some main factors affecting the welding deformation. Through the riveter “joint” size, we controlled the process parameters, post-welding processing, and other aspects. These measures had some practical significance to prevent, control, and reduce the deformation of welding.

Femtosecond transient absorption dynamics of close-packed gold nanocrystal monolayer arrays*1

NASA Astrophysics Data System (ADS)

Eah, Sang-Kee; Jaeger, Heinrich M.; Scherer, Norbert F.; Lin, Xiao-Min; Wiederrecht, Gary P.

2004-03-01

Femtosecond transient absorption spectroscopy is used to investigate hot electron dynamics of close-packed 6 nm gold nanocrystal monolayers. Morphology changes of the monolayer caused by the laser pump pulse are monitored by transmission electron microscopy. At low pump power, the monolayer maintains its structural integrity. Hot electrons induced by the pump pulse decay through electron-phonon (e-ph) coupling inside the nanocrystals with a decay constant that is similar to the value for bulk films. At high pump power, irreversible particle aggregation and sintering occur in the nanocrystal monolayer, which cause damping and peak shifting of the transient bleach signal.

Sub-Nanosecond Infrared Optical Parametric Pulse Generation in Periodically Poled Lithium Niobate Pumped by a Seeded Fiber Amplifier

DTIC Science & Technology

2008-02-01

Photonics. New York: John J. Wiley & Sons, Inc, 1991. 30. “How to (Maybe) Measure Laser Beam Quality” Prof. A. E. Siegman Tutorial Presentation at...Deterministic Nanosecond Laser -Induced Breakdown Thresholds in Pure and Yb3+ Doped Fused Silica,” Proc. of SPIE 6453 (2007) 37. Siegman , A.E...seeded at one end and pumped at the other end, using dichroic filters to protect the pump and seed lasers , creating a fiber amplifier. The seed laser

Topological Thouless pumping in graphene and 2D Dirac materials

NASA Astrophysics Data System (ADS)

Abergel, David; Pertsova, Anna

We present a comprehensive analysis of strain-induced topological Thouless pumping of charge and valley currents in graphene and 2D Dirac materials. We analyze the role of strain deformations with all possible symmetries and classify the charge and valley currents that are adiabatically pumped in response. These manifest as transport without an applied bias. The production of valley currents implies that strained Dirac materials are a candidate platform for valleytronic applications. Supported by ERC project DM-321031.

New methods for the development of pneumatic displacement pumps for cardiac assist.

PubMed

Knierbein, B; Rosarius, N; Reul, H; Rau, G

1990-11-01

The primary goal of the presented project was to develop a pump family with stroke volumes of 20, 50, 70 and 90 ml, which could be produced at low cost but with sufficient quality. The housing parts of the pump were thermoformed from technical semifinished materials. All blood contacting surfaces of the pump were coated with biomaterials in a controlled dipping process. During the design and fabrication process a professional CAD-system was used. This facilitated spatial presentations of pump components for first evaluations at the initial draft stages. The CAD-design data were then transformed to CNC-controlled lathes and mill's for the fabrication of pump tools. The stresses and strains of the moving blood pump components, such as membranes and valves, were precalculated by means of Finite-Element-Analysis (FEM). After completion of the pump, the internal flow fields were investigated by flow-visualization techniques using non-Newtonian test fluids, and the pump characteristics (function curves) were investigated in appropriate circulatory mock loops. The paper covers all above aspects from first draft to final fabrication and testing.

On-chip plasmon-induced transparency based on plasmonic coupled nanocavities

PubMed Central

Zhu, Yu; Hu, Xiaoyong; Yang, Hong; Gong, Qihuang

2014-01-01

On-chip plasmon-induced transparency offers the possibility of realization of ultrahigh-speed information processing chips. Unfortunately, little experimental progress has been made to date because it is difficult to obtain on-chip plasmon-induced transparency using only a single meta-molecule in plasmonic circuits. Here, we report a simple and efficient strategy to realize on-chip plasmon-induced transparency in a nanoscale U-shaped plasmonic waveguide side-coupled nanocavity pair. High tunability in the transparency window is achieved by covering the pair with different organic polymer layers. It is possible to realize ultrafast all-optical tunability based on pump light-induced refractive index change of a graphene cover layer. Compared with previous reports, the overall feature size of the plasmonic nanostructure is reduced by more than three orders of magnitude, while ultrahigh tunability of the transparency window is maintained. This work also provides a superior platform for the study of the various physical effects and phenomena of nonlinear optics and quantum optics. PMID:24435059

On-chip plasmon-induced transparency based on plasmonic coupled nanocavities.

PubMed

Zhu, Yu; Hu, Xiaoyong; Yang, Hong; Gong, Qihuang

2014-01-17

On-chip plasmon-induced transparency offers the possibility of realization of ultrahigh-speed information processing chips. Unfortunately, little experimental progress has been made to date because it is difficult to obtain on-chip plasmon-induced transparency using only a single meta-molecule in plasmonic circuits. Here, we report a simple and efficient strategy to realize on-chip plasmon-induced transparency in a nanoscale U-shaped plasmonic waveguide side-coupled nanocavity pair. High tunability in the transparency window is achieved by covering the pair with different organic polymer layers. It is possible to realize ultrafast all-optical tunability based on pump light-induced refractive index change of a graphene cover layer. Compared with previous reports, the overall feature size of the plasmonic nanostructure is reduced by more than three orders of magnitude, while ultrahigh tunability of the transparency window is maintained. This work also provides a superior platform for the study of the various physical effects and phenomena of nonlinear optics and quantum optics.

Dynamics of a single-atom electron pump.

PubMed

van der Heijden, J; Tettamanzi, G C; Rogge, S

2017-03-15

Single-electron pumps based on isolated impurity atoms have recently been experimentally demonstrated. In these devices the Coulomb potential of an atom creates a localised electron state with a large charging energy and considerable orbital level spacings, enabling robust charge capturing processes. In contrast to the frequently used gate-defined quantum dot pumps, which experience a strongly time-dependent potential, the confinement potential in these single-atom pumps is hardly affected by the periodic driving of the system. Here we describe the behaviour and performance of an atomic, single parameter, electron pump. This is done by considering the loading, isolating and unloading of one electron at the time, on a phosphorous atom embedded in a silicon double gate transistor. The most important feature of the atom pump is its very isolated ground state, which is populated through the fast loading of much higher lying excited states and a subsequent fast relaxation process. This leads to a substantial increase in pumping accuracy, and is opposed to the adverse role of excited states observed for quantum dot pumps due to non-adiabatic excitations. The pumping performance is investigated as a function of dopant position, revealing a pumping behaviour robust against the expected variability in atomic position.

Dynamics of a single-atom electron pump

PubMed Central

van der Heijden, J.; Tettamanzi, G. C.; Rogge, S.

2017-01-01

Single-electron pumps based on isolated impurity atoms have recently been experimentally demonstrated. In these devices the Coulomb potential of an atom creates a localised electron state with a large charging energy and considerable orbital level spacings, enabling robust charge capturing processes. In contrast to the frequently used gate-defined quantum dot pumps, which experience a strongly time-dependent potential, the confinement potential in these single-atom pumps is hardly affected by the periodic driving of the system. Here we describe the behaviour and performance of an atomic, single parameter, electron pump. This is done by considering the loading, isolating and unloading of one electron at the time, on a phosphorous atom embedded in a silicon double gate transistor. The most important feature of the atom pump is its very isolated ground state, which is populated through the fast loading of much higher lying excited states and a subsequent fast relaxation process. This leads to a substantial increase in pumping accuracy, and is opposed to the adverse role of excited states observed for quantum dot pumps due to non-adiabatic excitations. The pumping performance is investigated as a function of dopant position, revealing a pumping behaviour robust against the expected variability in atomic position. PMID:28295055

Generation of Ince-Gaussian beams in highly efficient, nanosecond Cr, Nd:YAG microchip lasers

NASA Astrophysics Data System (ADS)

Dong, J.; Ma, J.; Ren, Y. Y.; Xu, G. Z.; Kaminskii, A. A.

2013-08-01

Direct generation of higher-order Ince-Gaussian (IG) beams from laser-diode end-pumped Cr, Nd:YAG self-Q-switched microchip lasers was achieved with high efficiency and high repetition rate. An average output power of over 2 W was obtained at an absorbed pump power of 8.2 W a corresponding optical-to-optical efficiency of 25% was achieved. Various IG modes with nanosecond pulse width and peak power of over 2 kW were obtained in laser-diode pumped Cr, Nd:YAG microchip lasers under different pump power levels by applying a tilted, large area pump beam. The effect of the inversion population distribution induced by the tilted pump beam and nonlinear absorption of Cr4+-ions for different pump power levels on the oscillation of higher-order IG modes in Cr, Nd:YAG microchip lasers is addressed. The higher-order IG mode oscillation has a great influence on the laser performance of Cr, Nd:YAG microchip lasers.

Analysis of cavitation damage on the Space Shuttle main engine high pressure oxidizer turbopump

NASA Technical Reports Server (NTRS)

Stinebring, D. R.

1985-01-01

The performance of the Space Shuttle Main Engines (SSME) has met or exceeded specifications. However, the durability for selected components has not met the desired lifetime criteria. Thus, the High-Pressure Oxidizer Turbopump (HPOTP) has experienced cavitation erosion problems in a number of locations in the pump. An investigation was conducted, taking into account an analysis of the cavitation damage, the development of a flow model for the pump, and the recommendation of design changes which would increase the life expectancy of the unit. The present paper is concerned with the cavitation damage analysis. A model is presented which relates the heavy damage on the housing and over the inducer blades to unsteady blade surface cavitation. This cavitation occurs on the inducer blades in the wakes downstream of the pump inlet housing vanes.

Evidence of L-mode electromagnetic wave pumping of ionospheric plasma near geomagnetic zenith

NASA Astrophysics Data System (ADS)

Leyser, Thomas B.; James, H. Gordon; Gustavsson, Björn; Rietveld, Michael T.

2018-02-01

The response of ionospheric plasma to pumping by powerful HF (high frequency) electromagnetic waves transmitted from the ground into the ionosphere is the strongest in the direction of geomagnetic zenith. We present experimental results from transmitting a left-handed circularly polarized HF beam from the EISCAT (European Incoherent SCATter association) Heating facility in magnetic zenith. The CASSIOPE (CAScade, Smallsat and IOnospheric Polar Explorer) spacecraft in the topside ionosphere above the F-region density peak detected transionospheric pump radiation, although the pump frequency was below the maximum ionospheric plasma frequency. The pump wave is deduced to arrive at CASSIOPE through L-mode propagation and associated double (O to Z, Z to O) conversion in pump-induced radio windows. L-mode propagation allows the pump wave to reach higher plasma densities and higher ionospheric altitudes than O-mode propagation so that a pump wave in the L-mode can facilitate excitation of upper hybrid phenomena localized in density depletions in a larger altitude range. L-mode propagation is therefore suggested to be important in explaining the magnetic zenith effect.

Two-dimensional numerical simulation of O-mode to Z-mode conversion in the ionosphere

NASA Astrophysics Data System (ADS)

Cannon, P. D.; Honary, F.; Borisov, N.

2016-03-01

Experiments in the illumination of the F region of the ionosphere via radio frequency waves polarized in the ordinary mode (O-mode) have revealed that the magnitude of artificial heating-induced effects depends strongly on the inclination angle of the pump beam, with a greater modification to the plasma observed when the heating beam is directed close to or along the magnetic zenith direction. Numerical simulations performed using a recently developed finite-difference time-domain (FDTD) code are used to investigate the contribution of the O-mode to Z-mode conversion process to this effect. The aspect angle dependence and angular size of the radio window for which conversion of an O-mode pump wave to the Z-mode occurs is simulated for a variety of plasma density profiles including 2-D linear gradients representative of large-scale plasma depletions, density-depleted plasma ducts, and periodic field-aligned irregularities. The angular shape of the conversion window is found to be strongly influenced by the background plasma profile. If the Z-mode wave is reflected, it can propagate back toward the O-mode reflection region leading to resonant enhancement of the electric field in this region. Simulation results presented in this paper demonstrate that this process can make a significant contribution to the magnitude of electron density depletion and temperature enhancement around the resonance height and contributes to a strong dependence of the magnitude of plasma perturbation with the direction of the pump wave.

Mode-locked Ti:sapphire laser oscillators pumped by wavelength-multiplexed laser diodes

NASA Astrophysics Data System (ADS)

Sugiyama, Naoto; Tanaka, Hiroki; Kannari, Fumihiko

2018-05-01

We directly pumped a Ti:sapphire laser by combining 478 and 520 nm laser diodes to prevent the effect of absorption loss induced by the pump laser of shorter wavelengths (∼450 nm). We obtain a continuous-wave output power of 660 mW at a total incident pump power of 3.15 W. We demonstrate mode locking using a semiconductor saturable absorber mirror, and 126 fs pulses were obtained at a repetition rate of 192 MHz. At the maximum pump power, the average output power is 315 mW. Shorter mode-locked pulses of 42 and 48 fs were respectively achieved by Kerr-lens mode locking with average output powers of 280 and 360 mW at a repetition rate of 117 MHz.

Theoretical prediction of fast 3D AC electro-osmotic pumps.

PubMed

Bazant, Martin Z; Ben, Yuxing

2006-11-01

AC electro-osmotic (ACEO) pumps in microfluidics currently involve planar electrode arrays, but recent work on the underlying phenomenon of induced-charge electro-osmosis (ICEO) suggests that three-dimensional (3D) geometries may be exploited to achieve faster flows. In this paper, we present some new design principles for periodic 3D ACEO pumps, such as the "fluid conveyor belt" of ICEO flow over a stepped electrode array. Numerical simulations of these designs (using the standard low-voltage model) predict flow rates almost twenty times faster than existing planar ACEO pumps, for the same applied voltage and minimum feature size. These pumps may enable new portable or implantable lab-on-a-chip devices, since rather fast (mm s(-1)), tuneable flows should be attainable with battery voltages (<10 V).

Ca2+ Induces Spontaneous Dephosphorylation of a Novel P5A-type ATPase

PubMed Central

Sørensen, Danny Mollerup; Møller, Annette B.; Jakobsen, Mia K.; Jensen, Michael K.; Vangheluwe, Peter; Buch-Pedersen, Morten J.; Palmgren, Michael G.

2012-01-01

P5 ATPases constitute the least studied group of P-type ATPases, an essential family of ion pumps in all kingdoms of life. Although P5 ATPases are present in every eukaryotic genome analyzed so far, they have remained orphan pumps, and their biochemical function is obscure. We show that a P5A ATPase from barley, HvP5A1, locates to the endoplasmic reticulum and is able to rescue knock-out mutants of P5A genes in both Arabidopsis thaliana and Saccharomyces cerevisiae. HvP5A1 spontaneously forms a phosphorylated reaction cycle intermediate at the catalytic residue Asp-488, whereas, among all plant nutrients tested, only Ca2+ triggers dephosphorylation. Remarkably, Ca2+-induced dephosphorylation occurs at high apparent [Ca2+] (Ki = 0.25 mm) and is independent of the phosphatase motif of the pump and the putative binding site for transported ligands located in M4. Taken together, our results rule out that Ca2+ is a transported substrate but indicate the presence of a cytosolic low affinity Ca2+-binding site, which is conserved among P-type pumps and could be involved in pump regulation. Our work constitutes the first characterization of a P5 ATPase phosphoenzyme and points to Ca2+ as a modifier of its function. PMID:22730321

Effects of Pump-turbine S-shaped Characteristics on Transient Behaviours: Model Setup

NASA Astrophysics Data System (ADS)

Zeng, Wei; Yang, Jiandong; Hu, Jinhong

2017-04-01

Pumped storage stations undergo numerous transition processes, which make the pump turbines go through the unstable S-shaped region. The hydraulic transient in S-shaped region has normally been investigated through numerical simulations, while field experiments generally involve high risks and are difficult to perform. In this research, a pumped storage model composed of a piping system, two model units, two electrical control systems, a measurement system and a collection system was set up to study the transition processes. The model platform can be applied to simulate almost any hydraulic transition process that occurs in real power stations, such as load rejection, startup, frequency control and grid connection.

Apparatus and method for batch-wire continuous pumping

DOEpatents

Fassbender, Alexander G.

1996-01-01

The apparatus of the present invention contains at least one pressure vessel having a separator defining two chambers within each pressure vessel. The separator slideably seals the two chambers. Feedstock is placed within a second chamber adjoining the first chamber via a feedstock pump operating in a high volume low head mode. A pressurizer operates in a low volume high pressure mode to pressurize the working fluid and the feedstock in the pressure vessels to a process operating pressure. A circulating pump operates in a high volume, low head mode to circulate feedstock through the process. A fourth pump is used for moving feedstock and product at a pressure below the process operating pressure.

Exchangers man the pumps: Functional interplay between proton pumps and proton-coupled Ca(2+) exchangers

USDA-ARS?s Scientific Manuscript database

Tonoplast-localised proton-coupled Ca(2+) transporters encoded by cation/H(+) exchanger (CAX) genes play a critical role in sequestering Ca(2+) into the vacuole. These transporters may function in coordination with Ca(2+) release channels, to shape stimulus-induced cytosolic Ca(2+) elevations. Recen...

Observer-based perturbation extremum seeking control with input constraints for direct-contact membrane distillation process

NASA Astrophysics Data System (ADS)

Eleiwi, Fadi; Laleg-Kirati, Taous Meriem

2018-06-01

An observer-based perturbation extremum seeking control is proposed for a direct-contact membrane distillation (DCMD) process. The process is described with a dynamic model that is based on a 2D advection-diffusion equation model which has pump flow rates as process inputs. The objective of the controller is to optimise the trade-off between the permeate mass flux and the energy consumption by the pumps inside the process. Cases of single and multiple control inputs are considered through the use of only the feed pump flow rate or both the feed and the permeate pump flow rates. A nonlinear Lyapunov-based observer is designed to provide an estimation for the temperature distribution all over the designated domain of the DCMD process. Moreover, control inputs are constrained with an anti-windup technique to be within feasible and physical ranges. Performance of the proposed structure is analysed, and simulations based on real DCMD process parameters for each control input are provided.

46 CFR 154.534 - Cargo pumps and cargo compressors.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo pumps and cargo compressors. 154.534 Section 154... SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES Design, Construction and Equipment Cargo and Process Piping Systems § 154.534 Cargo pumps and cargo compressors. Cargo pumps and...

Thermodynamic and economic analysis of heat pumps for energy recovery in industrial processes

NASA Astrophysics Data System (ADS)

Urdaneta-B, A. H.; Schmidt, P. S.

1980-09-01

A computer code has been developed for analyzing the thermodynamic performance, cost and economic return for heat pump applications in industrial heat recovery. Starting with basic defining characteristics of the waste heat stream and the desired heat sink, the algorithm first evaluates the potential for conventional heat recovery with heat exchangers, and if applicable, sizes the exchanger. A heat pump system is then designed to process the residual heating and cooling requirements of the streams. In configuring the heat pump, the program searches a number of parameters, including condenser temperature, evaporator temperature, and condenser and evaporator approaches. All system components are sized for each set of parameters, and economic return is estimated and compared with system economics for conventional processing of the heated and cooled streams (i.e., with process heaters and coolers). Two case studies are evaluated, one in a food processing application and the other in an oil refinery unit.

Nonlinear photothermal mid-infrared spectroscopy

NASA Astrophysics Data System (ADS)

Totachawattana, Atcha; Erramilli, Shyamsunder; Sander, Michelle Y.

2016-10-01

Mid-infrared photothermal spectroscopy is a pump-probe technique for label-free and non-destructive sample characterization by targeting intrinsic vibrational modes. In this method, the mid-infrared pump beam excites a temperature-induced change in the refractive index of the sample. This laser-induced change in the refractive index is measured by a near-infrared probe laser using lock-in detection. At increased pump powers, emerging nonlinear phenomena not previously demonstrated in other mid-infrared techniques are observed. Nonlinear study of a 6 μm-thick 4-Octyl-4'-Cyanobiphenyl (8CB) liquid crystal sample is conducted by targeting the C=C stretching band at 1606 cm-1. At high pump powers, nonlinear signal enhancement and multiple pitchfork bifurcations of the spectral features are observed. An explanation of the nonlinear peak splitting is provided by the formation of bubbles in the sample at high pump powers. The discontinuous refractive index across the bubble interface results in a decrease in the forward scatter of the probe beam. This effect can be recorded as a bifurcation of the absorption peak in the photothermal spectrum. These nonlinear effects are not present in direct measurements of the mid-infrared beam. Evolution of the nonlinear photothermal spectrum of 8CB liquid crystal with increasing pump power shows enhancement of the absorption peak at 1606 cm-1. Multiple pitchfork bifurcations and spectral narrowing of the photothermal spectrum are demonstrated. This novel nonlinear regime presents potential for improved spectral resolution as well as a new regime for sample characterization in mid-infrared photothermal spectroscopy.

Process control strategy for ITER central solenoid operation

NASA Astrophysics Data System (ADS)

Maekawa, R.; Takami, S.; Iwamoto, A.; Chang, H.-S.; Forgeas, A.; Chalifour, M.

2016-12-01

ITER Central Solenoid (CS) pulse operation induces significant flow disturbance in the forced-flow Supercritical Helium (SHe) cooling circuit, which could impact primarily on the operation of cold circulator (SHe centrifugal pump) in Auxiliary Cold Box (ACB). Numerical studies using Venecia®, SUPERMAGNET and 4C have identified reverse flow at the CS module inlet due to the substantial thermal energy deposition at the inner-most winding. To assess the reliable operation of ACB-CS (dedicated ACB for CS), the process analyses have been conducted with a dynamic process simulation model developed by Cryogenic Process REal-time SimulaTor (C-PREST). As implementing process control of hydrodynamic instability, several strategies have been applied to evaluate their feasibility. The paper discusses control strategy to protect the centrifugal type cold circulator/compressor operations and its impact on the CS cooling.

Spectra- and temperature-dependent dynamics of directly end-pumped holmium lasers

NASA Astrophysics Data System (ADS)

Ji, Encai; Shen, Yijie; Nie, Mingming; Fu, Xing; Liu, Qiang

2017-04-01

We develop a theoretical model with high accuracy for directly end-pumped Ho3+ laser system considering the influences of ground-state depletion, energy transfer up-conversion, temperature-dependent cross sections, and pump spectra shift. The heat generation in our model is precisely evaluated by calculating the transition rates of non-radiation relaxation processes among manifolds and in-band relaxation processes based on a detailed analysis of energy levels structure of holmium ions. A spatial dynamic thermal iteration method, just developed by our group, is applied to describe the coupled influences between spatial thermal effects and pump spectra. This model is verified to both adapt to the narrow-band good beam-quality pumped case and the broad-band bad beam-quality pumped case, which is in accordance with our previous reported experimental results.

The CentriMag: a new optimized centrifugal blood pump with levitating impeller.

PubMed

Mueller, Juerg Peter; Kuenzli, Andreas; Reuthebuch, Oliver; Dasse, Kurt; Kent, Stella; Zuend, Gregor; Turina, Marko Ivan; Lachat, Mario Louis

2004-01-01

Blood pumps are routinely used for circulatory and pulmonary support. However, blood trauma and pump failure remain severe drawbacks of currently available pump models. This study evaluated the first clinical application of a new, totally bearingless centrifugal blood pump (CentriMag). A centrifugal pump consisting of an electromagnetic suspended impeller was used as a blood pump during beating-heart coronary artery bypass grafting in 11 patients (mean weight, 77.4 kg). Heparin in a bolus of 150 IU/kg body weight was administered, and activated clotting time was maintained at approximately 180 to 250 seconds during extracorporeal circulation. Pump-induced blood trauma was evaluated by measurement of plasma free hemoglobin (PFH), lactate dehydrogenase (LDH), hematocrit, total bilirubin, and platelet levels. Mean pump flow was 3.3 +/- 0.62 L/min, and mean pressure gradient through the oxygenator was 69 +/- 4 mm Hg. No pump dysfunction occurred during a mean application time of 105 +/- 26 minutes. Inspection of the pump housings showed no internal thrombus formation despite low-dose heparinization. Only slight hemolysis was observed with a mean PFH level of 1.96 micromol/L; LDH, 460 U/L; hematocrit, 33%; total bilirubin, 25 micromol/L; and platelets, 191 x 10(3)/microL. The bearingless CentriMag blood pump is a safe and reliable new device that produces only minimal hemolysis. It seems to be suited for long-term evaluation as a blood pump for extracorporeal membrane oxygenation or as ventricular assist device.

Laser intensity scaling through stimulated scattering in optical fibers

NASA Astrophysics Data System (ADS)

Russell, Timothy H.

The influence of stimulated scattering on laser intensity in fiber optic waveguides is examined. Stimulated Brillouin scattering (SBS) in long, multimode optical waveguides is found to generate a Stokes beam that propagates in the fiber LP01 mode. This characteristic of the Stokes beam was first applied to beam cleanup, where an aberrated pump generated a Gaussian-like Stokes beam. Additionally, the same process is found to combine multiple laser beams into a single spatially coherent source. The mean square difference between the two beams was used to measure the degree of spatial overlap, demonstrating spatial coherence between the Stokes beams even when the pump beams are not spatially correlated. This result is obtained regardless of whether the pump beams are at the same or different frequencies; producing two temporally coherent or incoherent Stokes beams respectively. Limitations in beam cleanup and combining are also examined to identify ways to overcome them. Output couplers are designed that could be used to spatially filter the Stokes beam from the pump, thus increasing the number of beams that could be combined. The combined power restriction induced by second order Stokes threshold is examined experimentally and theoretically and is not found to be a significant limitation. Finally, stimulated Raman scattering (SRS) beam cleanup is examined to overcome the stringent spectral requirements on the pump beams required by SBS. The last portion of the dissertation theoretically examines suppression of stimulated Raman scattering in fibers to eliminate the restriction this imposes on the power of a fiber laser or amplifier. The suppression was modeled using both a holmium dopant and adding a long period grating to the fiber. Both methods were shown to have a significant effect on the SRS threshold.

Self-powered Imbibing Microfluidic Pump by Liquid Encapsulation: SIMPLE.

PubMed

Kokalj, Tadej; Park, Younggeun; Vencelj, Matjaž; Jenko, Monika; Lee, Luke P

2014-11-21

Reliable, autonomous, internally self-powered microfluidic pumps are in critical demand for rapid point-of-care (POC) devices, integrated molecular-diagnostic platforms, and drug delivery systems. Here we report on a Self-powered Imbibing Microfluidic Pump by Liquid Encapsulation (SIMPLE), which is disposable, autonomous, easy to use and fabricate, robust, and cost efficient, as a solution for self-powered microfluidic POC devices. The imbibition pump introduces the working liquid which is sucked into a porous material (paper) upon activation. The suction of the working liquid creates a reduced pressure in the analytical channel and induces the sequential sample flow into the microfluidic circuits. It requires no external power or control and can be simply activated by a fingertip press. The flow rate can be programmed by defining the shape of utilized porous material: by using three different paper shapes with circular section angles 20°, 40° and 60°, three different volume flow rates of 0.07 μL s(-1), 0.12 μL s(-1) and 0.17 μL s(-1) are demonstrated at 200 μm × 600 μm channel cross-section. We established the SIMPLE pumping of 17 μL of sample; however, the sample volume can be increased to several hundreds of μL. To demonstrate the design, fabrication, and characterization of SIMPLE, we used a simple, robust and cheap foil-laminating fabrication technique. The SIMPLE can be integrated into hydrophilic or hydrophobic materials-based microfluidic POC devices. Since it is also applicable to large-scale manufacturing processes, we anticipate that a new chapter of a cost effective, disposable, autonomous POC diagnostic chip is addressed with this technical innovation.

Unraveling the Primary Isomerization Dynamics in Cyanobacterial Phytochrome Cph1 with Multi-pulse Manipulations.

PubMed

Kim, Peter W; Rockwell, Nathan C; Freer, Lucy H; Chang, Che-Wei; Martin, Shelley S; Lagarias, J Clark; Larsen, Delmar S

2013-07-20

The ultrafast mechanisms underlying the initial photoisomerization (P r → Lumi-R) in the forward reaction of the cyanobacterial photoreceptor Cph1 were explored with multipulse pump-dump-probe transient spectroscopy. A recently postulated multi-population model was used to fit the transient pump-dump-probe and dump-induced depletion signals. We observed dump-induced depletion of the Lumi-R photoproduct, demonstrating that photoisomerization occurs via evolution on both the excited- and ground-state electronic surfaces. Excited-state equilibrium was not observed, as shown via the absence of a dump-induced excited-state "Le Châtelier redistribution" of excited-state populations. The importance of incorporating the inhomogeneous dynamics of Cph1 in interpreting measured transient data is discussed.

Unraveling the Primary Isomerization Dynamics in Cyanobacterial Phytochrome Cph1 with Multi-pulse Manipulations

PubMed Central

Kim, Peter W.; Rockwell, Nathan C.; Freer, Lucy H.; Chang, Che-Wei; Martin, Shelley S.; Lagarias, J. Clark; Larsen, Delmar S.

2013-01-01

The ultrafast mechanisms underlying the initial photoisomerization (Pr → Lumi-R) in the forward reaction of the cyanobacterial photoreceptor Cph1 were explored with multipulse pump-dump-probe transient spectroscopy. A recently postulated multi-population model was used to fit the transient pump-dump-probe and dump-induced depletion signals. We observed dump-induced depletion of the Lumi-R photoproduct, demonstrating that photoisomerization occurs via evolution on both the excited- and ground-state electronic surfaces. Excited-state equilibrium was not observed, as shown via the absence of a dump-induced excited-state “Le Châtelier redistribution” of excited-state populations. The importance of incorporating the inhomogeneous dynamics of Cph1 in interpreting measured transient data is discussed. PMID:24143267

Spatial structure of plasma density perturbations, induced in the ionosphere modified by powerful HF radio waves: Review of experimental results

NASA Astrophysics Data System (ADS)

Frolov, Vladimir

2015-06-01

In the review, the results of experimental studies of spatial structure of small-, middle-, and large scale plasma density perturbations induced in the ionosphere by its pumping by powerful HF O-mode (ordinary) radio waves, are analyzed. It is shown that the region with induced plasma density perturbations occupied all ionosphere body from its E-region up to the topside ionosphere in the height and it has the horizontal length of about of 300-500 km. Peculiarities of generation of artificial ionosphere irregularities of different scale-lengths in the magnetic zenith region are stated. Experimental results obtained under conditions of ionosphere periodical pumping when the generation of travel ionosphere disturbances is revealed are also discussed.

Reconstruction-free sensitive wavefront sensor based on continuous position sensitive detectors.

PubMed

Godin, Thomas; Fromager, Michael; Cagniot, Emmanuel; Brunel, Marc; Aït-Ameur, Kamel

2013-12-01

We propose a new device that is able to perform highly sensitive wavefront measurements based on the use of continuous position sensitive detectors and without resorting to any reconstruction process. We demonstrate experimentally its ability to measure small wavefront distortions through the characterization of pump-induced refractive index changes in laser material. In addition, it is shown using computer-generated holograms that this device can detect phase discontinuities as well as improve the quality of sharp phase variations measurements. Results are compared to reference Shack-Hartmann measurements, and dramatic enhancements are obtained.

Simultaneous observations of electromagnetically induced transparency (EIT) and absorption (EIA) in a multi-level V-type system of 87Rb and theoretical simulation of the observed spectra using a multi-mode approach

NASA Astrophysics Data System (ADS)

Das, Bankim Chandra; Bhattacharyya, Dipankar; Das, Arpita; Chakrabarti, Shrabana; De, Sankar

2016-12-01

We report here simultaneous experimental observation of Electromagnetically Induced Transparency (EIT) and Electromagnetically Induced Absorption (EIA) in a multi-level V-type system in D2 transition of 87Rb, i.e., F =2 →F' with a strong pump and a weak probe beam. We studied the probe spectrum by locking the probe beam to the transition F =2 →F'=2 while the pump is scanned from F =2 →F' . EIA is observed for the open transition (F =2 →F'=2 ) whereas EIT is observed in the closed transition (F =2 →F'=3 ). Sub natural line-width is observed for the EIA. To simulate the observed spectra theoretically, Liouville equation for the three-level V-type system is solved analytically with a multi-mode approach for the density matrix elements. We assumed both the pump and the probe beams can couple the excited states. A multi-mode approach for the coherence terms facilitates the study of all the frequency contributions due to the pump and the probe fields. Since the terms contain higher harmonics of the pump and the probe frequencies, we expressed them in Fourier transformed forms. To simulate the probe spectrum, we have solved inhomogeneous difference equations for the coherence terms using the Green's function technique and continued fraction theory. The experimental line-widths of the EIT and the EIA are compared with our theoretical model. Our system can be useful in optical switching applications as it can be precisely tuned to render the medium opaque and transparent simultaneously.

Simultaneous observations of electromagnetically induced transparency (EIT) and absorption (EIA) in a multi-level V-type system of 87Rb and theoretical simulation of the observed spectra using a multi-mode approach.

PubMed

Das, Bankim Chandra; Bhattacharyya, Dipankar; Das, Arpita; Chakrabarti, Shrabana; De, Sankar

2016-12-14

We report here simultaneous experimental observation of Electromagnetically Induced Transparency (EIT) and Electromagnetically Induced Absorption (EIA) in a multi-level V-type system in D 2 transition of Rb87, i.e., F=2→F ' with a strong pump and a weak probe beam. We studied the probe spectrum by locking the probe beam to the transition F=2→F ' =2 while the pump is scanned from F=2→F ' . EIA is observed for the open transition (F=2→F ' =2) whereas EIT is observed in the closed transition (F=2→F ' =3). Sub natural line-width is observed for the EIA. To simulate the observed spectra theoretically, Liouville equation for the three-level V-type system is solved analytically with a multi-mode approach for the density matrix elements. We assumed both the pump and the probe beams can couple the excited states. A multi-mode approach for the coherence terms facilitates the study of all the frequency contributions due to the pump and the probe fields. Since the terms contain higher harmonics of the pump and the probe frequencies, we expressed them in Fourier transformed forms. To simulate the probe spectrum, we have solved inhomogeneous difference equations for the coherence terms using the Green's function technique and continued fraction theory. The experimental line-widths of the EIT and the EIA are compared with our theoretical model. Our system can be useful in optical switching applications as it can be precisely tuned to render the medium opaque and transparent simultaneously.

Dynamics of cavitating cascades. [transfer functions

NASA Technical Reports Server (NTRS)

Brennen, C. E.; Acosta, A. J.

1980-01-01

The unsteady dynamics of cavitating cascades and inducer pumps were studied with a view to understanding (and possibly predicting) the dynamic characteristics of these devices. The chronology of the research is summarized as well as the final conculsions for each task. The construction of a dynamic pump test facility and its use in making experimental measurements of the transfer function is described as well as tests conducted using a scale model of the low pressure liquid oxygen turbopump inducer in the shuttle main engine. Auto-oscillation and unsteady inlet flow characteristics are discussed in addition to blade cavity influence and bubbly cavitation.

Optomechanically-induced transparency in parity-time-symmetric microresonators

PubMed Central

Jing, H.; Özdemir, Şahin K.; Geng, Z.; Zhang, Jing; Lü, Xin-You; Peng, Bo; Yang, Lan; Nori, Franco

2015-01-01

Optomechanically-induced transparency (OMIT) and the associated slowing of light provide the basis for storing photons in nanoscale devices. Here we study OMIT in parity-time (PT)-symmetric microresonators with a tunable gain-to-loss ratio. This system features a sideband-reversed, non-amplifying transparency , i.e., an inverted-OMIT. When the gain-to-loss ratio is varied, the system exhibits a transition from a PT-symmetric phase to a broken-PT-symmetric phase. This PT-phase transition results in the reversal of the pump and gain dependence of the transmission rates. Moreover, we show that by tuning the pump power at a fixed gain-to-loss ratio, or the gain-to-loss ratio at a fixed pump power, one can switch from slow to fast light and vice versa. These findings provide new tools for controlling light propagation using nanofabricated phononic devices. PMID:26169253

Simplifications of the RELIEF flow tagging system for laboratory use. [Raman Excitation plus Laser Induced Electronic Fluorescence

NASA Technical Reports Server (NTRS)

Lempert, Walter R.; Zhang, Boying; Miles, Richard B.; Diskin, Glenn

1991-01-01

The use of an O2:He stimulated Raman cell to generate the Stokes beam for the Raman vibrational pumping step of the RELIEF (Raman Excitation plus Laser-Induced Electronic Fluorescence) flow tagging method is reported. Use of the Raman cell rather than a dye laser provides pump and Stokes beams which are automatically frequency matched and temporally and spatially overlapped. The Nd:YAG pump laser is operated multilongitudinal mode, which eliminates the need for injection seeding, resulting in decreased operation complexity and improved stability with respect to acoustic noise. Results are presented for 1st Stokes conversion efficiency and stimulated Brillouin backscattering loss and are compared to the case of pure O2. Scanning CARS measurements of the Q-branch lineshape for both pure O2 and the O2:He mixture are also presented.

Nonlinear Generation of Electromagnetic Waves through Induced Scattering by Thermal Plasma.

PubMed

Tejero, E M; Crabtree, C; Blackwell, D D; Amatucci, W E; Mithaiwala, M; Ganguli, G; Rudakov, L

2015-12-09

We demonstrate the conversion of electrostatic pump waves into electromagnetic waves through nonlinear induced scattering by thermal particles in a laboratory plasma. Electrostatic waves in the whistler branch are launched that propagate near the resonance cone. When the amplitude exceeds a threshold ~5 × 10(-6) times the background magnetic field, wave power is scattered below the pump frequency with wave normal angles (~59°), where the scattered wavelength reaches the limits of the plasma column. The scattered wave has a perpendicular wavelength that is an order of magnitude larger than the pump wave and longer than the electron skin depth. The amplitude threshold, scattered frequency spectrum, and scattered wave normal angles are in good agreement with theory. The results may affect the analysis and interpretation of space observations and lead to a comprehensive understanding of the nature of the Earth's plasma environment.

Relative phase noise induced impairment in CO-OFDM optical communication system with distributed fiber Raman amplifier.

PubMed

Wu, Jiadi; Cheng, Jingchi; Tang, Ming; Deng, Lei; Songnian, Fu; Shum, Perry Ping; Liu, Deming

2014-05-15

In this Letter, we demonstrate that the interplay between Raman pump relative intensity noise and cross-phase modulation leads to a relative phase noise (RPN) that brings non-negligible performance degradation to coherent optical orthogonal frequency-division multiplexing (CO-OFDM) transmission systems with co-pumped Raman amplification. By theoretical analysis and numerical simulation, we proved that RPN brings more system impairment in terms of Q-factor penalty than the single carrier system, and relatively larger walk-off between pump and signal helps to suppress the RPN induced impairment. A higher-order modulated signal is less tolerant to RPN than a lower-order signal. With the same spectral efficiency, the quadrature-amplitude modulation format shows better tolerance to RPN than phase-shift keying. The reported findings will be useful for the design and optimization of Raman amplified CO-OFDM multi-carrier transmission systems.

A physical model of the photo- and radiation-induced degradation of ytterbium-doped silica optical fibres

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mady, Franck, E-mail: franck.mady@unice.fr; Duchez, Jean-Bernard, E-mail: franck.mady@unice.fr; Mebrouk, Yasmine, E-mail: franck.mady@unice.fr

2014-10-21

We propose a model to describe the photo- or/and the radiation-induced darkening of ytterbium-doped silica optical fibers. This model accounts for the well-established experimental features of photo-darkening. Degradation behaviors predicted for fibers pumped in harsh environments are also fully confirmed by experimental data reported in the work by Duchez et al. (this proceeding), which gives a detailed characterization of the interplay between the effects of the pump and those of a superimposed ionizing irradiation (actual operation conditions in space-based applications for instance). In particular, dependences of the darkening build-up on the pump power, the total ionizing dose and the dosemore » rate are all correctly reproduced. The presented model is a ‘sufficient’ one, including the minimal physical ingredients required to reproduce experimental features. Refinements could be proposed to improve, e.g., quantitative kinetics.« less

Hydraulic refinement of an intraarterial microaxial blood pump.

PubMed

Siess, T; Reul, H; Rau, G

1995-05-01

Intravascularly operating microaxial pumps have been introduced clinically proving to be useful tools for cardiac assist. However, a number of complications have been reported in literature associated with the extra-corporeal motor and the flexible drive shaft cable. In this paper, a new pump concept is presented which has been mechanically and hydraulically refined during the developing process. The drive shaft cable has been replaced by a proximally integrated micro electric motor and an extra-corporeal power supply. The conduit between pump and power supply consists of only an electrical power cable within the catheter resulting in a device which is indifferent to kinking and small curvature radii. Anticipated insertion difficulties, as a result of a large outer pump diameter, led to a two-step approach with an initial 6,4mm pump version and a secondary 5,4mm version. Both pumps meet the hydraulic requirement of at least 2.5l/min at a differential pressure of 80-100 mmHg. The hydraulic refinements necessary to achieve the anticipated goal are based on ongoing hydrodynamic studies of the flow inside the pumps. Flow visualization on a 10:1 scale model as well as on 1:1 scale pumps have yielded significant improvements in the overall hydraulic performance of the pumps. One example of this iterative developing process by means of geometrical changes on the basis of flow visualization is illustrated for the 6.4mm pump.

FALCON reactor-pumped laser description and program overview

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1989-12-01

The FALCON (Fission Activated Laser CONcept) reactor-pumped laser program at Sandia National Laboratories is examining the feasibility of high-power systems pumped directly by the energy from a nuclear reactor. In this concept we use the highly energetic fission fragments from neutron induced fission to excite a large volume laser medium. This technology has the potential to scale to extremely large optical power outputs in a primarily self-powered device. A laser system of this type could also be relatively compact and capable of long run times without refueling.

Scaling Behavior of the Spin Pumping Effect in Ferromagnet-Platinum Bilayers

NASA Astrophysics Data System (ADS)

Czeschka, F. D.; Dreher, L.; Brandt, M. S.; Weiler, M.; Althammer, M.; Imort, I.-M.; Reiss, G.; Thomas, A.; Schoch, W.; Limmer, W.; Huebl, H.; Gross, R.; Goennenwein, S. T. B.

2011-07-01

We systematically measured the dc voltage VISH induced by spin pumping together with the inverse spin Hall effect in ferromagnet-platinum bilayer films. In all our samples, comprising ferromagnetic 3d transition metals, Heusler compounds, ferrite spinel oxides, and magnetic semiconductors, VISH invariably has the same polarity, and scales with the magnetization precession cone angle. These findings, together with the spin mixing conductance derived from the experimental data, quantitatively corroborate the present theoretical understanding of spin pumping in combination with the inverse spin Hall effect.

MEANS AND METHOD FOR PRODUCING A VACUUM

DOEpatents

Otavka, M.A.

1960-08-01

A new method is given for starting the operation of evapor-ion vacuum pumps. Ordinarily this type of pump is started by inducing an electric field with the vacuum chamber; however, by placing such an electric field in the chamber at the outset, a glow discharge may be initiated which is harmful to the pump. The procedure consists of using a negative electric field during which time only gettering action takes place; subsequently when the field reverses after a sufficient reduction of the number of gaseous particles in the chamber both gettering and ionizing takes place.

Medium-power diode-pumped Nd:BaY2F8 laser

NASA Astrophysics Data System (ADS)

Agnesi, Antonio; Guandalini, Annalisa; Lucca, Andrea; Sani, Elisa; Toncelli, Alessandra; Tonelli, Mauro; dell'Acqua, Stefano

2003-05-01

We report what is to our knowledge the first Nd:BaY2F8 (Nd:BaYF) laser pumped with a multiwatt fiber-coupled diode array tuned at approximately 804 nm. As much as 2.4 W were obtained with 6.2 W of absorbed pump power, showing efficient operation (51% slope efficiency), excellent beam quality (M2=1.1), and weak thermal lensing. Small intracavity losses (<1%) were measured, indicating both reduced thermally induced aberrations and good optical quality of the laser crystal.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schearer, L.D.; Leduc, M.

Over 250 mW of CW laser emission at 1084 nm is obtained from Nd:LiNbO{sub 3} when the rod is end-pumped along the crystalline {open quote}{ital y}{close quote} axis by 1 W from a Kr{sup +} laser at 752 nm. The laser can be tuned over 3 nm at the 1084 nm peak with a thin, uncoated etalon in the cavity. Thresholds of 30 mW of absorbed pump power were obtained with a weak output coupler, rising to 220 mW with a 35% transmitting output mirror. No pump-induced photorefractive effects were observed.

Identification and evolution of drug efflux pump in clinical Enterobacter aerogenes strains isolated in 1995 and 2003.

PubMed

Chevalier, Jacqueline; Mulfinger, Céline; Garnotel, Eric; Nicolas, Pierre; Davin-Régli, Anne; Pagès, Jean-Marie

2008-09-12

The high mortality impact of infectious diseases will increase due to accelerated evolution of antibiotic resistance in important human pathogens. Development of antibiotic resistance is a evolutionary process inducing the erosion of the effectiveness of our arsenal of antibiotics. Resistance is not necessarily limited to a single class of antibacterial agents but may affect many unrelated compounds; this is termed 'multidrug resistance' (MDR). The major mechanism of MDR is the active expulsion of drugs by bacterial pumps; the treatment of gram negative bacterial infections is compromised due to resistance mechanisms including the expression of efflux pumps that actively expel various usual antibiotics (beta-lactams, quinolones, ...). Enterobacter aerogenes has emerged among Enterobacteriaceae associated hospital infections during the last twenty years due to its faculty of adaptation to antibiotic stresses. Clinical isolates of E. aerogenes belonging to two strain collections isolated in 1995 and 2003 respectively, were screened to assess the involvement of efflux pumps in antibiotic resistance. Drug susceptibility assays were performed on all bacterial isolates and an efflux pump inhibitor (PAbetaN) previously characterized allowed to decipher the role of efflux in the resistance. Accumulation of labelled chloramphenicol was monitored in the presence of an energy poison to determine the involvement of active efflux on the antibiotic intracellular concentrations. The presence of the PAbetaN-susceptible efflux system was also identified in resistant E. aerogenes strains. For the first time a noticeable increase in clinical isolates containing an efflux mechanism susceptible to pump inhibitor is report within an 8 year period. After the emergence of extended spectrum beta-lactamases in E. aerogenes and the recent characterisation of porin mutations in clinical isolates, this study describing an increase in inhibitor-susceptible efflux throws light on a new step in the evolution of mechanism in E. aerogenes.

Identification and Evolution of Drug Efflux Pump in Clinical Enterobacter aerogenes Strains Isolated in 1995 and 2003

PubMed Central

Garnotel, Eric; Nicolas, Pierre; Davin-Régli, Anne; Pagès, Jean-Marie

2008-01-01

Background The high mortality impact of infectious diseases will increase due to accelerated evolution of antibiotic resistance in important human pathogens. Development of antibiotic resistance is a evolutionary process inducing the erosion of the effectiveness of our arsenal of antibiotics. Resistance is not necessarily limited to a single class of antibacterial agents but may affect many unrelated compounds; this is termed ‘multidrug resistance’ (MDR). The major mechanism of MDR is the active expulsion of drugs by bacterial pumps; the treatment of Gram negative bacterial infections is compromised due to resistance mechanisms including the expression of efflux pumps that actively expel various usual antibiotics (ß-lactams, quinolones, …). Methodology/Principal Findings Enterobacter aerogenes has emerged among Enterobacteriaceae associated hospital infections during the last twenty years due to its faculty of adaptation to antibiotic stresses. Clinical isolates of E. aerogenes belonging to two strain collections isolated in 1995 and 2003 respectively, were screened to assess the involvement of efflux pumps in antibiotic resistance. Drug susceptibility assays were performed on all bacterial isolates and an efflux pump inhibitor (PAßN) previously characterized allowed to decipher the role of efflux in the resistance. Accumulation of labelled chloramphenicol was monitored in the presence of an energy poison to determine the involvement of active efflux on the antibiotic intracellular concentrations. The presence of the PAßN-susceptible efflux system was also identified in resistant E. aerogenes strains. Conclusions/Significance For the first time a noticeable increase in clinical isolates containing an efflux mechanism susceptible to pump inhibitor is report within an 8 year period. After the emergence of extended spectrum ß-lactamases in E. aerogenes and the recent characterisation of porin mutations in clinical isolates, this study describing an increase in inhibitor-susceptible efflux throws light on a new step in the evolution of mechanism in E. aerogenes. PMID:18787654

Cascade generation in Al laser induced plasma

NASA Astrophysics Data System (ADS)

Nagli, Lev; Gaft, Michael; Raichlin, Yosef; Gornushkin, Igor

2018-05-01

We found cascade IR generation in Al laser induced plasma. This generation includes doublet transitions 3s 25s 2S1/2 → 3s24p 2P1/2,3/2 → 3s24s 2S1/2; corresponding to strong lines at 2110 and 2117 nm, and much weaker lines at 1312-1315 nm. The 3s25s2S 1/2 starting IR generation level is directly pumped from the 3s23p 2P3/2 ground level. The starting level for UV generation at 396.2 nm (transitions 3s24s 2S1/2 → 4p 2P3/2) is populated due to the fast collisional processes in the plasma plume. These differences led to different time and special dependences on the lasing in the IR and UV spectral range within the aluminum laser induced plasma.

Investigation of laser induced breakdown in liquid nitromethane using nanosecond shadowgraphy

NASA Astrophysics Data System (ADS)

Guo, Wencan; Zheng, Xianxu; Yu, Guoyang; Zhao, Jun; Zeng, Yangyang; Liu, Cangli

2016-09-01

A nanosecond time-resolved shadowgraphy is performed to observe a laser-induced breakdown in nitromethane. The digital delays are introduced between a pump beam and an illumination light to achieve a measuring range from 40 ns to 100 ms, which enable us to study the shock wave propagation, bubble dynamics, and other process of the laser-induced breakdown. Compared with distilled water, there are two obvious differences observed in nitromethane: (1) the production of a non-evaporative gas at the final stage, and (2) an absence of the secondary shock wave after the first collapse of the bubble. We also calculated the bubble energy in nitromethane and distilled water under a different incident energy. The results indicate that the bubble energy in nitromethane is more than twice as large as that in water. It is suggested that chemical reactions contribute to the releasing of energy.

Table-top two-color soft X-ray laser by means of Ni-like plasmas

DOE Office of Scientific and Technical Information (OSTI.GOV)

Masoudnia, Leili; Ruiz-Lopez, Mabel; Bleiner, Davide, E-mail: davide.bleiner@empa.ch

2016-04-15

Laser-produced Ni-like plasmas are known as active media for extreme ultraviolet lasing, with the flexibility to two-color lasing. Two-color laser generation is very complex at accelerator facilities. In this work, plasma lasing at the 3d{sup 9}4d{sup 1}(J = 0) → 3d{sup 9}4p{sup 1}(J = 1) (collisional-pumping process) and the 3d{sup 9}4f{sup 1}(J = 1) → 3d{sup 9}4d{sup 1}(J = 1) (photo-pumping process) transitions is studied experimentally and computationally. Several key characteristics of collisional- and photo-pumping laser, such as divergence, pointing stability, and intensity have been investigated. The measurements showed different pulse characteristics for the two lasing processes affected by plasma inhomogeneity in temperature and density. Analytical expressions of these characteristicsmore » for both collisional- and photo-pumping are derived. It is found that the plasma that maximizes the photo-pumping lasing is 20% hotter and 70% denser than the plasma that optimizes the collisional-pumping lasing. The gain of collisional pumping is ≈4 times higher than the gain for the photo-pumping. The gain lifetime is a factor of ≈5.2 larger for the monopole-pumping. Similarly, the gain thickness is a factor of ≈1.8 larger. It is also found that the gain build-up time for collisional- and photo-pumping is 0.7 ps and 0.9 ps, respectively, whereas the build-up length-scale is 11.5 μm and 6.3 μm, respectively.« less

A highly reliable cryogenic mixing pump with no mechanical moving parts

NASA Astrophysics Data System (ADS)

Chen, W.; Niblick, A. L.

2017-12-01

This paper presents the design and preliminary test results of a novel cryogenic mixing pump based on magnetocaloric effect. The mixing pump is developed to enable long-term cryogenic propellant storage in space by preventing thermal stratification of cryogens in storage tanks. The mixing pump uses an innovative thermodynamic process to generate fluid jets to promote fluid mixing, eliminating the need for mechanical pumps. Its innovative mechanism uses a solid magnetocaloric material to alternately vaporize and condense the cryogen in the pumping chamber, and thus control the volume of the fluid inside the pumping chamber to produce pumping action. The pump is capable of self-priming and can generate a high-pressure rise. This paper discusses operating mechanism and design consideration of the pump, introduces the configuration of a brassboard cryogenic pump, and presents the preliminary test results of the pump with liquid nitrogen.

SHINE Vacuum Pump Test Verification

DOE Office of Scientific and Technical Information (OSTI.GOV)

Morgan, Gregg A; Peters, Brent

2013-09-30

Normetex pumps used world-wide for tritium service are no longer available. DOE and other researchers worldwide have spent significant funds characterizing this pump. Identification of alternate pumps is required for performance and compatibility with tritium gas. Many of the pumps that could be used to meet the functional performance requirements (e.g. pressure and flow conditions) of the Normetex pump have features that include the use of polymers or oils and greases that are not directly compatible with tritium service. This study assembles a test system to determine the flow characteristics for candidate alternate pumps. These tests are critical to themore » movement of tritium through the SHINE Tritium Purification System (TPS). The purpose of the pump testing is two-fold: (1) obtain baseline vacuum pump characteristics for an alternate (i.e. ''Normetex replacement'') pump intended for use in tritium service; and (2) verify that low pressure hydrogen gas can be transported over distances up to 300 feet by the candidate pumps. Flow rates and nominal system pressures have been identified for the SHINE Mo-99 production process Tritium Purification System (TPS). To minimize the line sizes for the transfer of low pressure tritium from the Neutron Driver Accelerator System (NDAS) to the primary processing systems in the TPS, a ''booster'' pump has been located near the accelerator in the design. A series of pump tests were performed at various configurations using hydrogen gas (no tritium) to ensure that this concept is practical and maintains adequate flow rates and required pressures. This report summarizes the results of the tests that have been performed using various pump configurations. The current design of the Tritium Purification System requires the ''booster'' pump to discharge to or to be backed by another vacuum pump. Since Normetex pumps are no longer manufactured, a commercially available Edwards scroll pump will be used to back the booster pump. In this case the ''booster pump'' is an Adixen Molecular Drag Pump (MDP 5011) and the backing pump is an Edwards (nXDS15iC) scroll pump. Various configurations of the two pumps and associated lengths of 3/4 inch tubing (0 feet to 300 feet) were used in combination with hydrogen and nitrogen flow rates ranging from 25-400 standard cubic centimeters per minute (sccm) to determine whether the proposed pump configuration meets the design criteria for SHINE. The results of this study indicate that even under the most severe conditions (300 feet of tubing and 400 sccm flow rate) the Adixen 5011 MDP can serve as a booster pump to transport gases from the accelerator (NDAS) to the TPS. The Target Gas Receiving System pump (Edwards nXDS15iC) located approximately 300 feet from the accelerator can effectively back the Adixen MDP. The molecular drag pump was able to maintain its full rotational speed even when the flow rate was 400 sccm hydrogen or nitrogen and 300 feet of tubing was installed between the drag pump and the Edwards scroll pump. In addition to maintaining adequate rotation, the pressure in the system was maintained below the target pressure of 30 torr for all flow rates, lengths of tubing, and process gases. This configuration is therefore adequate to meet the SHINE design requirements in terms of flow and pressure.« less

Diffractive Combiner of Single-Mode Pump Laser-Diode Beams

NASA Technical Reports Server (NTRS)

Liu, Duncan; Wilson, Daniel; Qiu, Yueming; Forouhar, Siamak

2007-01-01

An optical beam combiner now under development would make it possible to use the outputs of multiple single-mode laser diodes to pump a neodymium: yttrium aluminum garnet (Nd:YAG) nonplanar ring oscillator (NPRO) laser while ensuring that the laser operates at only a single desired frequency. Heretofore, an Nd:YAG NPRO like the present one has been pumped by a single multimode laser-diode beam delivered via an optical fiber. It would be desirable to use multiple pump laser diodes to increase reliability beyond that obtainable from a single pump laser diode. However, as explained below, simplistically coupling multiple multimode laser-diode beams through a fiber-optic combiner would entail a significant reduction in coupling efficiency, and lasing would occur at one or more other frequencies in addition to the single desired frequency. Figure 1 schematically illustrates the principle of operation of a laser-diode-pumped Nd:YAG NPRO. The laser beam path is confined in a Nd:YAG crystal by means of total internal reflections on the three back facets and a partial-reflection coating on the front facet. The wavelength of the pump beam - 808 nm - is the wavelength most strongly absorbed by the Nd:YAG crystal. The crystal can lase at a wavelength of either 1,064 nm or 1,319 nm - which one depending on the optical coating on the front facet. A thermal lens effect induced by the pump beam enables stable lasing in the lowest-order transverse electromagnetic mode (the TEM00 mode). The frequency of this laser is very stable because of the mechanical stability of the laser crystal and the unidirectional nature of the lasing. The unidirectionality is a result of the combined effects of (1) a Faraday rotation induced by an externally applied magnetic field and (2) polarization associated with non-normal incidence and reflection on the front facet.

All-optical 40Gbit/s format conversion from NRZ to RZ based on SFG in a PPLN waveguide

NASA Astrophysics Data System (ADS)

Wang, Jian; Sun, Junqiang

2006-01-01

A novel all-optical 40Gbit/s NRZ-to-RZ data format conversion scheme based on sum-frequency generation (SFG) interaction in a periodically poled LiNbO 3 (PPLN) waveguide is presented for the first time, using a Mach-Zehnder interferometer (MZI). The conversion mechanism relies on the combination of attenuation and nonlinear phase shift Φ NL induced on the signal field. The performance of the conversion is numerically evaluated, with the result showing that it is more effective to yield Φ NL when appropriately phase mismatched for SFG process but Φ NL~0 when quasi-phase-matching (QPM). Compared with the cascaded second-order nonlinear interactions (SHG+DFG) with the influence of walk-off effect, a high conversion efficiency and good performance are achieved with peak power 500mw and width 2ps of the pump, which can be used in super high-speed situation (40Gbit/s and above). Finally, the inverse process of SFG and corresponding walk-off effect are analyzed and the optimum arrangement of power is proposed, showing that proper power, pump width, and waveguide length are necessary for achieving a satisfied conversion effect.

Proton pump inhibition and cancer therapeutics: A specific tumor targeting or it is a phenomenon secondary to a systemic buffering?

PubMed

Spugnini, Enrico; Fais, Stefano

2017-04-01

One of the unsolved mysteries in oncology includes the strategies that cancer cells adopt to cope with an adverse microenvironment. However, we knew, from the Warburg's discovery that through their metabolism based on sugar fermentation, cancer cells acidify their microenvironment and this progressive acidification induces a selective pressure, leading to the development of very malignant cells entirely armed to survive in the hostile microenvironment generated by their own metabolism. In the last decades a primordial role for proton exchangers has been supported as a key tumor advantage in facing off the acidic milieu. Proton exchangers do not allow intracellular acidification through a continuous elimination of H+ either outside the cells or within the internal vacuoles. This article wants to comment a translational process through that led to the preclinical demonstration that a class of proton pump inhibitors (PPI) exploited worldwide for peptic ulcer treatment and gastroprotection are indeed powerful chemosensitizers as well. In this process we achieved the clinical proof of concept that PPI may well be included in new anti-cancer strategies with a solid background and rationale. Copyright © 2017 Elsevier Ltd. All rights reserved.

3D numerical modeling of hyporheic exchange processes in fractal riverbed

NASA Astrophysics Data System (ADS)

Lee, A.; Aubeneau, A.

2017-12-01

The subsurface region receiving stream water is known as the hyporheic zone and the flow of water in and out of this zone is called hyporheic exchange. The hyporheic zone is populated by biofilms and is a hotspot for nutrient uptake and contaminant transformation. Traditionally, pumping models predicting the head distribution over the riverbed boundary are used to obtain the velocity field in the subsurface. However, past research has largely overlooked the nonlinearity of the turbulent flow above the bumpy riverbed. The main objective of this research is to investigate the effect of spatial and temporal heterogeneity created by turbulent flow on hyporheic exchange and residence time distribution in fractal channel beds. The 3-D fractal riverbed is created from the power spectrum. Large-Eddy Simulation is used to provide the pressure field over the benthic boundary. Finally, Darcian fluxes in the sub-surface are calculated and hyporheic travel times computed using random walks. Surface and subsurface transport processes are represented explicitly and can be studied in detail. Our results suggest that (1) Eddies and wakes around the dunes force the exchange (2) The bigger the dunes, the greater the influence of turbulence (3) Turbulence induces more exchange than pumping predicts.

Hydrogeology and water quality of the Floridan aquifer system and effects of Lower Floridan aquifer pumping on the Upper Floridan aquifer at Fort Stewart, Georgia

USGS Publications Warehouse

Clarke, John S.; Cherry, Gregory C.; Gonthier, Gerard

2011-01-01

Test drilling, field investigations, and digital modeling were completed at Fort Stewart, GA, during 2009?2010, to assess the geologic, hydraulic, and water-quality characteristics of the Floridan aquifer system and evaluate the effect of Lower Floridan aquifer (LFA) pumping on the Upper Floridan aquifer (UFA). This work was performed pursuant to the Georgia Environmental Protection Division interim permitting strategy for new wells completed in the LFA that requires simulation to (1) quantify pumping-induced aquifer leakage from the UFA to LFA, and (2) identify the equivalent rate of UFA pumping that would produce the same maximum drawdown in the UFA that anticipated pumping from LFA well would induce. Field investigation activities included (1) constructing a 1,300-foot (ft) test boring and well completed in the LFA (well 33P028), (2) constructing an observation well in the UFA (well 33P029), (3) collecting drill cuttings and borehole geophysical logs, (4) collecting core samples for analysis of vertical hydraulic conductivity and porosity, (5) conducting flowmeter and packer tests in the open borehole within the UFA and LFA, (6) collecting depth-integrated water samples to assess basic ionic chemistry of various water-bearing zones, and (7) conducting aquifer tests in new LFA and UFA wells to determine hydraulic properties and assess interaquifer leakage. Using data collected at the site and in nearby areas, model simulation was used to assess the effects of LFA pumping on the UFA. Borehole-geophysical and flowmeter data indicate the LFA at Fort Stewart consists of limestone and dolomitic limestone between depths of 912 and 1,250 ft. Flowmeter data indicate the presence of three permeable zones at depth intervals of 912-947, 1,090-1,139, and 1,211?1,250 ft. LFA well 33P028 received 50 percent of the pumped volume from the uppermost permeable zone, and about 18 and 32 percent of the pumped volume from the middle and lowest permeable zones, respectively. Chemical constituent concentrations increased with depth, and water from all permeable zones contained sulfate at concentrations that exceeded the U.S. Environmental Protection Agency secondary maximum contaminant level of 250 milligrams per liter. A 72-hour aquifer test pumped LFA well 33P028 at 740 gallons per minute (gal/min), producing about 39 ft of drawdown in the pumped well and about 0.4 foot in nearby UFA well 33P029. Simulation using the U.S. Geological Survey finite-difference code MODFLOW was used to determine long-term, steady-state flow in the Floridan aquifer system, assuming the LFA well was pumped continuously at a rate of 740 gal/min. Simulated steady-state drawdown in the LFA was identical to that observed in pumped LFA well 33P028 at the end of the 72-hour test, with values larger than 1 ft extending 4.4 square miles symmetrically around the pumped well. Simulated steady-state drawdown in the UFA resulting from pumping in LFA well 33P028 exceeded 1 ft within a 1.4-square-mile circular area, and maximum drawdown in the UFA was 1.1 ft. Leakage from the UFA through the Lower Floridan confining unit contributed about 98 percent of the water to the well; lateral flow from specified-head model boundaries contributed about 2 percent. About 80 percent of the water supplied to LFA well 33P028 originated from within 1 mile of the well, and 49 percent was derived from within 0.5 mile of the well. Vertical hydraulic gradients and vertical leakage are progressively higher near the LFA pumped well which results in a correspondingly higher contribution of water from the UFA to the pumped well at distances closer to the pumped well. Simulated pumping-induced interaquifer leakage from the UFA to the LFA totaled 725 gal/min (1.04 million gallons per day), whereas simulated pumping at 205 gal/min (0.3 million gallons per day) from UFA well 33P029 produced the equivalent maximum drawdown as pumping LFA well 33P028 at 740 gal/min during the aquifer test. This equivalent pumpin

Characterization and regulation of the resistance-nodulation-cell division-type multidrug efflux pumps MdtABC and MdtUVW from the fire blight pathogen Erwinia amylovora.

PubMed

Pletzer, Daniel; Weingart, Helge

2014-07-11

The Gram-negative bacterium Erwinia amylovora is the causal agent of the devastating disease fire blight in rosaceous plants such as apple, pear, quince, raspberry, and cotoneaster. In order to survive and multiply in a host, microbes must be able to circumvent the toxic effects of antimicrobial plant compounds, such as flavonoids and tannins. E. amylovora uses multidrug efflux transporters that recognize and actively export toxic compounds out of the cells. Here, two heterotrimeric resistance-nodulation-cell division (RND)-type multidrug efflux pumps, MdtABC and MdtUVW, from E. amylovora were identified. These RND systems are unusual in that they contain two different RND proteins forming a functional pump. To find the substrate specificities of the two efflux systems, we overexpressed the transporters in a hypersensitive mutant lacking the major RND pump AcrB. Both transporters mediated resistance to several flavonoids, fusidic acid and novobiocin. Additionally, MdtABC mediated resistance towards josamycin, bile salts and silver nitrate, and MdtUVW towards clotrimazole. The ability of the mdtABC- and mdtUVW-deficient mutants to multiply in apple rootstock was reduced. Quantitative RT-PCR analyses revealed that the expression of the transporter genes was induced during infection of apple rootstock. The polyphenolic plant compound tannin, as well as the heavy metal salt tungstate was found to induce the expression of mdtABC. Finally, the expression of the mdtABC genes was shown to be regulated by BaeR, the response regulator of the two-component system BaeSR, a cell envelope stress response system that controls the adaptive responses to changes in the environment. The expression of MdtABC and MdtUVW is induced during growth of E. amylovora in planta. We identified the plant polyphenol tannin as inducer of mdtABC expression. The reduced ability of the mdtABC- and mdtUVW-deficient mutants to multiply in apple rootstock suggests that the efflux pumps are involved in resistance to plant antimicrobials, maybe including flavonoids, which were identified as substrates of both pumps. Furthermore, we found that the mdtABC operon belongs to the regulon of the two-component regulator BaeR suggesting a role of this RND transporter in the cell envelope stress response of E. amylovora.

Characterization and regulation of the Resistance-Nodulation-Cell Division-type multidrug efflux pumps MdtABC and MdtUVW from the fire blight pathogen Erwinia amylovora

PubMed Central

2014-01-01

Background The Gram-negative bacterium Erwinia amylovora is the causal agent of the devastating disease fire blight in rosaceous plants such as apple, pear, quince, raspberry, and cotoneaster. In order to survive and multiply in a host, microbes must be able to circumvent the toxic effects of antimicrobial plant compounds, such as flavonoids and tannins. E. amylovora uses multidrug efflux transporters that recognize and actively export toxic compounds out of the cells. Here, two heterotrimeric resistance-nodulation-cell division (RND)-type multidrug efflux pumps, MdtABC and MdtUVW, from E. amylovora were identified. These RND systems are unusual in that they contain two different RND proteins forming a functional pump. Results To find the substrate specificities of the two efflux systems, we overexpressed the transporters in a hypersensitive mutant lacking the major RND pump AcrB. Both transporters mediated resistance to several flavonoids, fusidic acid and novobiocin. Additionally, MdtABC mediated resistance towards josamycin, bile salts and silver nitrate, and MdtUVW towards clotrimazole. The ability of the mdtABC- and mdtUVW-deficient mutants to multiply in apple rootstock was reduced. Quantitative RT-PCR analyses revealed that the expression of the transporter genes was induced during infection of apple rootstock. The polyphenolic plant compound tannin, as well as the heavy metal salt tungstate was found to induce the expression of mdtABC. Finally, the expression of the mdtABC genes was shown to be regulated by BaeR, the response regulator of the two-component system BaeSR, a cell envelope stress response system that controls the adaptive responses to changes in the environment. Conclusions The expression of MdtABC and MdtUVW is induced during growth of E. amylovora in planta. We identified the plant polyphenol tannin as inducer of mdtABC expression. The reduced ability of the mdtABC- and mdtUVW-deficient mutants to multiply in apple rootstock suggests that the efflux pumps are involved in resistance to plant antimicrobials, maybe including flavonoids, which were identified as substrates of both pumps. Furthermore, we found that the mdtABC operon belongs to the regulon of the two-component regulator BaeR suggesting a role of this RND transporter in the cell envelope stress response of E. amylovora. PMID:25012600

Space Shuttle Main Engine Low Pressure Oxidizer Turbo-Pump Inducer Dynamic Environment Characterization through Water Model and Hot-Fire Testing

NASA Technical Reports Server (NTRS)

Arellano, Patrick; Patton, Marc; Schwartz, Alan; Stanton, David

2006-01-01

The Low Pressure Oxidizer Turbopump (LPOTP) inducer on the Block II configuration Space Shuttle Main Engine (SSME) experienced blade leading edge ripples during hot firing. This undesirable condition led to a minor redesign of the inducer blades. This resulted in the need to evaluate the performance and the dynamic environment of the redesign, relative to the current configuration, as part of the design acceptance process. Sub-scale water model tests of the two inducer configurations were performed, with emphasis on the dynamic environment due to cavitation induced vibrations. Water model tests were performed over a wide range of inlet flow coefficient and pressure conditions, representative of the scaled operating envelope of the Block II SSME, both in flight and in ground hot-fire tests, including all power levels. The water test hardware, facility set-up, type and placement of instrumentation, the scope of the test program, specific test objectives, data evaluation process and water test results that characterize and compare the two SSME LPOTP inducers are discussed. In addition, dynamic characteristics of the two water models were compared to hot fire data from specially instrumented ground tests. In general, good agreement between the water model and hot fire data was found, which confirms the value of water model testing for dynamic characterization of rocket engine turbomachinery.

Voltage Dependence of Proton Pumping by Bacteriorhodopsin Mutants with Altered Lifetime of the M Intermediate

PubMed Central

Geibel, Sven; Lörinczi, Èva; Bamberg, Ernst; Friedrich, Thomas

2013-01-01

The light-driven proton pump bacteriorhodopsin (BR) from Halobacterium salinarum is tightly regulated by the [H+] gradient and transmembrane potential. BR exhibits optoelectric properties, since spectral changes during the photocycle are kinetically controlled by voltage, which predestines BR for optical storage or processing devices. BR mutants with prolonged lifetime of the blue-shifted M intermediate would be advantageous, but the optoelectric properties of such mutants are still elusive. Using expression in Xenopus oocytes and two-electrode voltage-clamping, we analyzed photocurrents of BR mutants with kinetically destabilized (F171C, F219L) or stabilized (D96N, D96G) M intermediate in response to green light (to probe H+ pumping) and blue laser flashes (to probe accumulation/decay of M). These mutants have divergent M lifetimes. As for BR-WT, this strictly correlates with the voltage dependence of H+ pumping. BR-F171C and BR-F219L showed photocurrents similar to BR-WT. Yet, BR-F171C showed a weaker voltage dependence of proton pumping. For both mutants, blue laser flashes applied during and after green-light illumination showed reduced M accumulation and shorter M lifetime. In contrast, BR-D96G and BR-D96N exhibited small photocurrents, with nonlinear current-voltage curves, which increased strongly in the presence of azide. Blue laser flashes showed heavy M accumulation and prolonged M lifetime, which accounts for the strongly reduced H+ pumping rate. Hyperpolarizing potentials augmented these effects. The combination of M-stabilizing and -destabilizing mutations in BR-D96G/F171C/F219L (BR-tri) shows that disruption of the primary proton donor Asp-96 is fatal for BR as a proton pump. Mechanistically, M destabilizing mutations cannot compensate for the disruption of Asp-96. Accordingly, BR-tri and BR-D96G photocurrents were similar. However, BR-tri showed negative blue laser flash-induced currents even without actinic green light, indicating that Schiff base deprotonation in BR-tri exists in the dark, in line with previous spectroscopic investigations. Thus, M-stabilizing mutations, including the triple mutation, drastically interfere with electrochemical H+ gradient generation. PMID:24019918

Ekman pumping mechanism driving precipitation anomalies in response to equatorial heating

NASA Astrophysics Data System (ADS)

Hamouda, Mostafa E.; Kucharski, Fred

2018-03-01

In this paper some basic mechanisms for rainfall teleconnections to a localized tropical sea surface temperature anomaly are re-visited using idealized AGCM aqua-planet simulations. The dynamical response is generally in good agreement with the Gill-Matsuno theory. The mechanisms analyzed are (1) the stabilization of the tropical troposphere outside the heating region, (2) the Walker circulation modification and (3) Ekman pumping induced by the low-level circulation responses. It is demonstrated that all three mechanisms, and in particular (2) and (3), contribute to the remote rainfall teleconnections. However, mechanism (3) best coincides with the overall horizontal structure of rainfall responses. It is shown by using the models boundary layer parameterization that low-level vertical velocities are indeed caused by Ekman pumping and that this induces vertical velocities in the whole tropospheric column through convective feedbacks. Also the modification of the responses due to the presence of idealized warm pools is investigated. It is shown that warm pools modify the speed of the tropical waves, consistent with Doppler shifts and are thus able to modify the Walker circulation adjustments and remote rainfall responses. The sensitivity of the responses, and in particular the importance of the Ekman pumping mechanism, to large variations in the drag coefficient is also tested, and it is shown that the Ekman pumping mechanism is robust for a wide range of values.

Several hundred kHz repetition rate nanosecond pulses amplification in Er-Yb co-doped fiber amplifier

NASA Astrophysics Data System (ADS)

Yang, Weiqiang; Yin, Ke; Zhang, Bin; Xue, Guanghui; Hou, Jing

2014-07-01

We have experimentally investigated several hundred kHz repetition rate 1,550-nm nanosecond pulses amplification in Er-Yb co-doped fiber amplifier (EYDFA). The experimental setup has three stage fiber amplifiers. At the output of the second stage EYDFA, Yb3+ ions induced amplified spontaneous emission (Yb-ASE) is not observed owing to the low pump power. In the third stage EYDFA, a simultaneously seeded 1,064-nm continuous-wave laser is used to control Yb-ASE. Without any additional 1,064-nm signal, significantly backward Yb-ASE which caused loss-induced heat accumulation at the input port of the pump combiner can be observed. The monitored temperature at the input port of the pump combiner rapidly grows from 30 to 80 °C when the pump power is turned from 20 to 32 W. When a 196-mW forward 1,064-nm laser is added, the monitored backward Yb-ASE power is significantly declined, and the monitored temperature is kept below 35 °C. But, the additional signal caused a large power fraction at 1,064 nm in the output laser. In our experiment at the maximum pump power of 48.5 W, the total output power is 20 W with ~6.4-W 1,550-nm pulsed laser and ~13-W 1,064-nm continuous-wave laser.

Spontaneous and induced emission of XeCl* excimer molecules under pumping of Xe - CCl4 and Ar - Xe - CCl4 gas mixtures with a low CCl4 content by fast electrons and uranium fission fragments

NASA Astrophysics Data System (ADS)

Mis'kevich, A. I.; Guo, J.; Dyuzhov, Yu A.

2013-11-01

The spontaneous and induced emission of XeCl* excimer molecules upon excitation of Xe - CCl4 and Ar - Xe - CCl4 gas mixtures with a low CCl4 content by high-energy charged particles [a pulsed high-energy electron beam and products of neutron nuclear reaction 235U(n, f)] has been experimentally studied. The electron energy was 150 keV, and the pump current pulse duration and amplitude were 5 ns and 5 A, respectively. The energy of fission fragments did not exceed 100 MeV, the duration of the neutron pump pulse was 200 μs, and the specific power contribution to the gas was about 300 W cm-3. Electron beam pumping in a cell 4 cm long with a cavity having an output mirror transmittance of 2.7% gives rise to lasing on the B → X transition in the XeCl* molecule (λ = 308 nm) with a gain α = 0.0085 cm-1 and fluorescence efficiency η ≈ 10%. Pumping by fission fragments in a 250-cm-long cell with a cavity formed by a highly reflecting mirror and a quartz window implements amplified spontaneous emission (ASE) with an output power of 40 - 50 kW sr-1 and a base ASE pulse duration of ~200 ms.

Time-resolved measurement of single pulse femtosecond laser-induced periodic surface structure formation induced by a pre-fabricated surface groove.

PubMed

Kafka, K R P; Austin, D R; Li, H; Yi, A Y; Cheng, J; Chowdhury, E A

2015-07-27

Time-resolved diffraction microscopy technique has been used to observe the formation of laser-induced periodic surface structures (LIPSS) from the interaction of a single femtosecond laser pulse (pump) with a nano-scale groove mechanically formed on a single-crystal Cu substrate. The interaction dynamics (0-1200 ps) was captured by diffracting a time-delayed, frequency-doubled pulse (probe) from nascent LIPSS formation induced by the pump with an infinity-conjugate microscopy setup. The LIPSS ripples are observed to form asynchronously, with the first one forming after 50 ps and others forming sequentially outward from the groove edge at larger time delays. A 1-D analytical model of electron heating including both the laser pulse and surface plasmon polariton excitation at the groove edge predicts ripple period, melt spot diameter, and qualitatively explains the asynchronous time-evolution of LIPSS formation.

Feasibility study on an energy-saving desiccant wheel system with CO2 heat pump

NASA Astrophysics Data System (ADS)

Liu, Yefeng; Meng, Deren; Chen, Shen

2018-02-01

In traditional desiccant wheel, air regeneration process occurs inside an open loop, and lots of energy is consumed. In this paper, an energy-saving desiccant wheel system with CO2 heat pump and closed loop air regeneration is proposed. The general theory and features of the desiccant wheel are analysed. The main feature of the proposed system is that the air regeneration process occurs inside a closed loop, and a CO2 heat pump is utilized inside this loop for the air regeneration process as well as supplying cooling for the process air. The simulation results show that the proposed system can save significant energy.

Ocean Biological Pump Sensitivities and Implications for Climate Change Impacts

NASA Technical Reports Server (NTRS)

Romanou, Anastasia

2013-01-01

The ocean is one of the principal reservoirs of CO2, a greenhouse gas, and therefore plays a crucial role in regulating Earth's climate. Currently, the ocean sequesters about a third of anthropogenic CO2 emissions, mitigating the human impact on climate. At the same time, the deeper ocean represents the largest carbon pool in the Earth System and processes that describe the transfer of carbon from the surface of the ocean to depth are intimately linked to the effectiveness of carbon sequestration.The ocean biological pump (OBP), which involves several biogeochemical processes, is a major pathway for transfer of carbon from the surface mixed layer into the ocean interior. About 75 of the carbon vertical gradient is due to the carbon pump with only 25 attributed to the solubility pump. However, the relative importance and role of the two pumps is poorly constrained. OBP is further divided to the organic carbon pump (soft tissue pump) and the carbonate pump, with the former exporting about 10 times more carbon than the latter through processes like remineralization.Major uncertainties about OBP, and hence in the carbon uptake and sequestration, stem from uncertainties in processes involved in OBP such as particulate organicinorganic carbon sinkingsettling, remineralization, microbial degradation of DOC and uptakegrowth rate changes of the ocean biology. The deep ocean is a major sink of atmospheric CO2 in scales of hundreds to thousands of years, but how the export efficiency (i.e. the fraction of total carbon fixation at the surface that is transported at depth) is affected by climate change remains largely undetermined. These processes affect the ocean chemistry (alkalinity, pH, DIC, particulate and dissolved organic carbon) as well as the ecology (biodiversity, functional groups and their interactions) in the ocean. It is important to have a rigorous, quantitative understanding of the uncertainties involved in the observational measurements, the models and the projections of future changes.

Optical silencing of body wall muscles induces pumping inhibition in Caenorhabditis elegans

PubMed Central

Takahashi, Megumi

2017-01-01

Feeding, a vital behavior in animals, is modulated depending on internal and external factors. In the nematode Caenorhabditis elegans, the feeding organ called the pharynx ingests food by pumping driven by the pharyngeal muscles. Here we report that optical silencing of the body wall muscles, which drive the locomotory movement of worms, affects pumping. In worms expressing the Arch proton pump or the ACR2 anion channel in the body wall muscle cells, the pumping rate decreases after activation of Arch or ACR2 with light illumination, and recovers gradually after terminating illumination. Pumping was similarly inhibited by illumination in locomotion-defective mutants carrying Arch, suggesting that perturbation of locomotory movement is not critical for pumping inhibition. Analysis of mutants and cell ablation experiments showed that the signals mediating the pumping inhibition response triggered by activation of Arch with weak light are transferred mainly through two pathways: one involving gap junction-dependent mechanisms through pharyngeal I1 neurons, which mediate fast signals, and the other involving dense-core vesicle-dependent mechanisms, which mediate slow signals. Activation of Arch with strong light inhibited pumping strongly in a manner that does not rely on either gap junction-dependent or dense-core vesicle-dependent mechanisms. Our study revealed a new aspect of the neural and neuroendocrine controls of pumping initiated from the body wall muscles. PMID:29281635

Summary of Recent Inducer Testing at MSFC and Future Plans

NASA Technical Reports Server (NTRS)

Skelley, Stephen

2003-01-01

This viewgraph presentation covers water flow tests on the RS-83 Main LOX Inducer for the Space Shuttle Main Engine (SSME). The presentation lists recent water tests on the SSME liquid oxygen (LOX) pump inducer, includes images and diagrams of the water test facility at Marshall Space Flight Center (MSFC), profiles inducer hydrodynamic forces, and diagrams the performance of the RS-83 inducer.

Synchronization and Random Triggering of Lymphatic Vessel Contractions

PubMed Central

Baish, James W.; Kunert, Christian; Padera, Timothy P.; Munn, Lance L.

2016-01-01

The lymphatic system is responsible for transporting interstitial fluid back to the bloodstream, but unlike the cardiovascular system, lacks a centralized pump-the heart–to drive flow. Instead, each collecting lymphatic vessel can individually contract and dilate producing unidirectional flow enforced by intraluminal check valves. Due to the large number and spatial distribution of such pumps, high-level coordination would be unwieldy. This leads to the question of how each segment of lymphatic vessel responds to local signals that can contribute to the coordination of pumping on a network basis. Beginning with elementary fluid mechanics and known cellular behaviors, we show that two complementary oscillators emerge from i) mechanical stretch with calcium ion transport and ii) fluid shear stress induced nitric oxide production (NO). Using numerical simulation and linear stability analysis we show that the newly identified shear-NO oscillator shares similarities with the well-known Van der Pol oscillator, but has unique characteristics. Depending on the operating conditions, the shear-NO process may i) be inherently stable, ii) oscillate spontaneously in response to random disturbances or iii) synchronize with weak periodic stimuli. When the complementary shear-driven and stretch-driven oscillators interact, either may dominate, producing a rich family of behaviors similar to those observed in vivo. PMID:27935958

Synchronization and Random Triggering of Lymphatic Vessel Contractions.

PubMed

Baish, James W; Kunert, Christian; Padera, Timothy P; Munn, Lance L

2016-12-01

The lymphatic system is responsible for transporting interstitial fluid back to the bloodstream, but unlike the cardiovascular system, lacks a centralized pump-the heart-to drive flow. Instead, each collecting lymphatic vessel can individually contract and dilate producing unidirectional flow enforced by intraluminal check valves. Due to the large number and spatial distribution of such pumps, high-level coordination would be unwieldy. This leads to the question of how each segment of lymphatic vessel responds to local signals that can contribute to the coordination of pumping on a network basis. Beginning with elementary fluid mechanics and known cellular behaviors, we show that two complementary oscillators emerge from i) mechanical stretch with calcium ion transport and ii) fluid shear stress induced nitric oxide production (NO). Using numerical simulation and linear stability analysis we show that the newly identified shear-NO oscillator shares similarities with the well-known Van der Pol oscillator, but has unique characteristics. Depending on the operating conditions, the shear-NO process may i) be inherently stable, ii) oscillate spontaneously in response to random disturbances or iii) synchronize with weak periodic stimuli. When the complementary shear-driven and stretch-driven oscillators interact, either may dominate, producing a rich family of behaviors similar to those observed in vivo.

Measurement of heat pump processes induced by laser radiation

NASA Technical Reports Server (NTRS)

Garbuny, M.; Henningsen, T.

1983-01-01

A series of experiments was performed in which a suitably tuned CO2 laser, frequency doubled by a Tl3AsSe37 crystal, was brought into resonance with a P-line or two R-lines in the fundamental vibration spectrum of CO. Cooling or heating produced by absorption in CO was measured in a gas-thermometer arrangement. P-line cooling and R-line heating could be demonstrated, measured, and compared. The experiments were continued with CO mixed with N2 added in partial pressures from 9 to 200 Torr. It was found that an efficient collisional resonance energy transfer from CO to N2 existed which increased the cooling effects by one to two orders of magnitude over those in pure CO. Temperature reductions in the order of tens of degrees Kelvin were obtained by a single pulse in the core of the irradiated volume. These measurements followed predicted values rather closely, and it is expected that increase of pulse energies and durations will enhance the heat pump effects. The experiments confirm the feasibility of quasi-isentropic engines which convert laser power into work without the need for heat rejection. Of more immediate potential interest is the possibility of remotely powered heat pumps for cryogenic use, such applications are discussed to the extent possible at the present stage.

Investigation on efficiency declines due to spectral overlap between LDAs pump and laser medium in high power double face pumped slab laser

NASA Astrophysics Data System (ADS)

Lang, Ye; Chen, Yanzhong; Liao, Lifen; Guo, Guangyan; He, Jianguo; Fan, Zhongwei

2018-03-01

In high power diode lasers, the input cooling water temperature would affect both output power and output spectrum. In double face pumped slab laser, the spectrum of two laser diode arrays (LDAs) must be optimized for efficiency reason. The spectrum mismatch of two LDAs would result in energy storing decline. In this work, thermal induced efficiency decline due to spectral overlap between high power LDAs and laser medium was investigated. A numerical model was developed to describe the energy storing variation with changing LDAs cooling water temperature and configuration (series/parallel connected). A confirmatory experiment was conducted using a double face pumped slab module. The experiment results show good agreements with simulations.

Quantum Noise Reduction with Pulsed Light in Optical Fibers.

NASA Astrophysics Data System (ADS)

Bergman, Keren

Optical fibers offer considerable advantages over bulk nonlinear media for the generation of squeezed states. This thesis reports on experimental investigations of reducing quantum noise by means of squeezing in nonlinear fiber optic interferometers. Fibers have low insertion loss which allows for long interaction lengths. High field intensities are easily achieved in the small cores of single mode fibers. Additionally, the nonlinear process employed is self phase modulation or the Kerr effect, whose broad band nature requires no phase matching and can be exploited with ultra-short pulses of high peak intensity. All these advantageous features of fibers result in easily obtained large nonlinear phase shifts and subsequently large squeezing parameters. By the self phase modulation process a correlation is produced between the phase and amplitude fluctuations of the optical field. The attenuated or squeezed quadrature has a lower noise level than the initial level associated with the coherent state field before propagation. The resulting reduced quantum noise quadrature can be utilized to improve the sensitivity of a phase measuring instrument such as an interferometer. Because the Kerr nonlinearity is a degenerate self pumping process, the squeezed noise is at the same frequency as the pump field. Classical pump noise can therefore interfere with the desired measurement of the quantum noise reduction. The most severe noise process is the phase noise caused by thermally induced index modulation of the fiber. This noise termed Guided Acoustic Wave Brillouin Scattering, or GAWBS, by previous researchers is studied and analyzed. Experiments performed to overcome GAWBS successfully with several schemes are described. An experimental demonstration of an interferometric measurement with better sensitivity than the standard quantum limit is described. The results lead to new understandings into the limitations of quantum noise reduction that can be achieved in the laboratory. (Copies available exclusively from MIT Libraries, Rm. 14-0551, Cambridge, MA 02139-4307. Ph. 617-253-5668; Fax 617-253-1690.).

Hypotonic stimulation of the Na+ active transport in frog skeletal muscle: role of the cytoskeleton

PubMed Central

Venosa, R A

2003-01-01

Hypotonicity produces a marked activation of the Na+ pump in frog sartorius muscle. The increase in net Na+ efflux under hypotonic conditions occurs despite the reductions in [Na+]i that are due to fibre swelling and Na+ loss. The pump density (ouabain binding) increases not only upon reduction of the medium osmotic pressure (π) from its normal value (π= 1) to one-half (π= 0.5), but also in muscles that are returned to π= 1 after equilibration in π= 2 medium. The equilibration in π= 2 medium does not affect pump density. Ouabain-binding increments cannot be ascribed to a rise in the Na+–K+ exchange rate of a fixed number of pumps: they also occurred in the continued presence of a saturating concentration of ouabain (50 μm). Under those conditions, the π= 1 →π= 0.5 transfer produced a 43 % increase in pump sites, while the π= 2 →π= 1 transfer induced a rise of 46 %. Actinomycin D did not alter the stimulation of Na+ extrusion elicited by hypotonicity, suggesting that de novo synthesis of pumps was not involved in the increase of the apparent number of pump sites. Disruption of microtubules by colchicine (100 μm) and intermediate filaments by acrylamide (4 mm) did not alter the hypotonic effect. Likewise, genistein (100 μm), a specific inhibitor of tyrosine kinase, did not affect significantly the hypotonic response. Microfilament-disrupting agents like cytochalasin B (5 μm) and latrunculin B (10 μm) reduced the increase in Na+ efflux induced by π= 1 →π= 0.5 transfer by about 35 % and 72 %, respectively. Latrunculin B reduced the increases in pump density generated by π= 1 →π= 0.5 and π= 2 →π= 1 transfers by about 79 % and 91 %, respectively. The results suggest that the membrane stretch due to hypotonic fibre volume increase would promote a microfilament-mediated insertion of submembranous spare Na+ pumps in the sarcolemma and, consequently, the rise in active Na+ transport. PMID:12598593

Observation of strong stimulated photorefractive scattering and self-pumped phase conjugation in LiNbO3:Mg in the ultraviolet

NASA Astrophysics Data System (ADS)

Qiao, Haijun; Tomita, Yasuo; Xu, Jingjun; Wu, Qiang; Zhang, Guoquan; Zhang, Guangyin

2005-09-01

We report on the observation of diffusion-dominant photorefraction and light-induced nonlinear forward and backward scattering in highly Mg-doped LiNbO3 at 351 nm. We also demonstrate what we believe to be the first continuous-wave self-pumped phase conjugation via stimulated photorefractive backscattering in the ultraviolet.

Effects of pumping strategies on pesticide concentration of a drinking water well

NASA Astrophysics Data System (ADS)

Aisopou, A.; Bjerg, P. L.; Binning, P. J.; Albrechtsen, H.

2011-12-01

Groundwater is an important source of drinking water production in many countries including Denmark. This requires high quality groundwater that meets the standards of the European Water Framework Directive. Yet as a result of agricultural activitity, deposition and previous handling, pesticides are frequently found in groundwater and can raise a substantial problem for ground water abstraction. The concentration of this contamination may vary between different layers. The heterogeneity of the subsurface geology and the depth of the drinking water well's screen are important parameters that affect the resulting contamination of the abstracted groundwater. The pesticide concentration in wells may also be affected by the pumping strategy because pumping can alter the structure of the flow field, the flowpath of water going to the well and subsequently the age of water at the well. The purpose of this study was to examine numerically the effects of pumping on pesticide contamination of drinking water wells using a reactive transport model in a hypothetical aquifer system resembling a typical Danish well field. The application history of the pesticides is crucial. This can be taken into account by assessing the effects of pumping on water age distribution along the well. Three compounds with different application histories were considered: an old banned pesticide MCPP (Mecoprop) which is mobile and relatively persistent in deeper aquifers, and a highly applied, biodegradable and strongly sorbing pesticide glyphosate, and its degradation product AMPA. A steady state flow field was first computed. A well field was then introduced and different pumping regimes were applied for a period of 180 years; a low-rate pumping, a high-rate pumping and a varying pumping regime. A constant application rate at the surface was assumed for the application period of each pesticide. The pre-abstraction age distribution of the water in the system was first estimated using a steady-state flow and transport simulation. These water ages were then used as the initial conditions for the transient simulations. The results of the simulations showed that the range of water ages contributing to the well increased during pumping and was substantially affected by the pumping rate. High pesticide concentrations were persistent in the well 40 to 100 years after they were banned, due to the high residence times in the aquifer. Large changes in simulated pesticides concentrations at the well occurred during pumping. The pesticide concentration reaching the well was affected by the pumping regime and the pesticide application history and properties. A higher pumping rate induced a higher pesticide concentration peak at the well of shorter duration, while a lower pumping rate induced a lower concentration peak of longer duration. The long term scenarios revealed that at high pumping rates MCPP would disappear 40 years after its application end year, while glyphosate concentrations increase and reach a plateau, which is highly dependent on the pumping rate. The findings of the study help understand the results of groundwater monitoring programmes and can be used for the quantitative evaluation of management and pumping strategies for the long-term supply of safe potable groundwater.

The Effect of Pulsatile Versus Nonpulsatile Blood Flow on Viscoelasticity and Red Blood Cell Aggregation in Extracorporeal Circulation

PubMed Central

Ahn, Chi Bum; Kang, Yang Jun; Kim, Myoung Gon; Yang, Sung; Lim, Choon Hak; Son, Ho Sung; Kim, Ji Sung; Lee, So Young; Son, Kuk Hui; Sun, Kyung

2016-01-01

Background Extracorporeal circulation (ECC) can induce alterations in blood viscoelasticity and cause red blood cell (RBC) aggregation. In this study, the authors evaluated the effects of pump flow pulsatility on blood viscoelasticity and RBC aggregation. Methods Mongrel dogs were randomly assigned to two groups: a nonpulsatile pump group (n=6) or a pulsatile pump group (n=6). After ECC was started at a pump flow rate of 80 mL/kg/min, cardiac fibrillation was induced. Blood sampling was performed before and at 1, 2, and 3 hours after ECC commencement. To eliminate bias induced by hematocrit and plasma, all blood samples were adjusted to a hematocrit of 45% using baseline plasma. Blood viscoelasticity, plasma viscosity, hematocrit, arterial blood gas analysis, central venous O2 saturation, and lactate were measured. Results The blood viscosity and aggregation index decreased abruptly 1 hour after ECC and then remained low during ECC in both groups, but blood elasticity did not change during ECC. Blood viscosity, blood elasticity, plasma viscosity, and the aggregation index were not significantly different in the groups at any time. Hematocrit decreased abruptly 1 hour after ECC in both groups due to dilution by the priming solution used. Conclusion After ECC, blood viscoelasticity and RBC aggregation were not different in the pulsatile and nonpulsatile groups in the adult dog model. Furthermore, pulsatile flow did not have a more harmful effect on blood viscoelasticity or RBC aggregation than nonpulsatile flow. PMID:27298790

The Effect of Pulsatile Versus Nonpulsatile Blood Flow on Viscoelasticity and Red Blood Cell Aggregation in Extracorporeal Circulation.

PubMed

Ahn, Chi Bum; Kang, Yang Jun; Kim, Myoung Gon; Yang, Sung; Lim, Choon Hak; Son, Ho Sung; Kim, Ji Sung; Lee, So Young; Son, Kuk Hui; Sun, Kyung

2016-06-01

Extracorporeal circulation (ECC) can induce alterations in blood viscoelasticity and cause red blood cell (RBC) aggregation. In this study, the authors evaluated the effects of pump flow pulsatility on blood viscoelasticity and RBC aggregation. Mongrel dogs were randomly assigned to two groups: a nonpulsatile pump group (n=6) or a pulsatile pump group (n=6). After ECC was started at a pump flow rate of 80 mL/kg/min, cardiac fibrillation was induced. Blood sampling was performed before and at 1, 2, and 3 hours after ECC commencement. To eliminate bias induced by hematocrit and plasma, all blood samples were adjusted to a hematocrit of 45% using baseline plasma. Blood viscoelasticity, plasma viscosity, hematocrit, arterial blood gas analysis, central venous O2 saturation, and lactate were measured. The blood viscosity and aggregation index decreased abruptly 1 hour after ECC and then remained low during ECC in both groups, but blood elasticity did not change during ECC. Blood viscosity, blood elasticity, plasma viscosity, and the aggregation index were not significantly different in the groups at any time. Hematocrit decreased abruptly 1 hour after ECC in both groups due to dilution by the priming solution used. After ECC, blood viscoelasticity and RBC aggregation were not different in the pulsatile and nonpulsatile groups in the adult dog model. Furthermore, pulsatile flow did not have a more harmful effect on blood viscoelasticity or RBC aggregation than nonpulsatile flow.

Temporal evolution of near-surface chlorophyll over cyclonic eddy lifecycles in the southeastern Pacific

NASA Astrophysics Data System (ADS)

Huang, Jie; Xu, Fanghua; Zhou, Kuanbo; Xiu, Peng; Lin, Yanluan

2017-08-01

Temporal evolution of near-surface chlorophyll (CHL) associated with mesoscale eddies over entire eddy lifespan is complicated. Based on satellite measurements and a reanalysis data set, we identify and quantify major temporal and spatial CHL responses in cyclonic eddies in the southeastern Pacific, and explore the associated mechanisms. Only few temporal CHL variations can be directly linked to the four primary mechanisms: "eddy pumping," "eddy trapping," "eddy stirring," and "eddy-induced Ekman pumping." About 80% of the temporal CHL variations are too complex to be explained by a single mechanism. Five characteristic CHL responses, including classic dipoles (CD), positive-dominant dipoles (PD), negative-dominant dipoles (ND), positive monopoles (PM), and negative monopoles (NM) are identified using the self-organizing map (SOM). CD, a dominant response induced primarily by "eddy stirring," has a continued increasing of frequency of occurrence with time, although its contribution to the total CHL variability remains low. As the secondary prominent response, NM has two peaks of frequency of occurrence at eddy formation and maturation stages, mainly accounted by "eddy trapping" after eddy breakup and "eddy-induced Ekman pumping," respectively. The sum of frequency of occurrence of PD and PM are comparable to that of NM. The initial positive CHL at eddy formation stage is associated with "eddy trapping." The significant positive CHL increase from the eddy intensification to early decay stage is mainly attributed to "eddy pumping." Although the frequency of occurrence of ND is the smallest, its contribution to negative CHL anomalies is unnegligible.

Remotely powered distributed microfluidic pumps and mixers based on miniature diodes.

PubMed

Chang, Suk Tai; Beaumont, Erin; Petsev, Dimiter N; Velev, Orlin D

2008-01-01

We demonstrate new principles of microfluidic pumping and mixing by electronic components integrated into a microfluidic chip. The miniature diodes embedded into the microchannel walls rectify the voltage induced between their electrodes from an external alternating electric field. The resulting electroosmotic flows, developed in the vicinity of the diode surfaces, were utilized for pumping or mixing of the fluid in the microfluidic channel. The flow velocity of liquid pumped by the diodes facing in the same direction linearly increased with the magnitude of the applied voltage and the pumping direction could be controlled by the pH of the solutions. The transverse flow driven by the localized electroosmotic flux between diodes oriented oppositely on the microchannel was used in microfluidic mixers. The experimental results were interpreted by numerical simulations of the electrohydrodynamic flows. The techniques may be used in novel actively controlled microfluidic-electronic chips.

Observation of stimulated Mie-Bragg scattering from large-size-gold-nanorod suspension in water

NASA Astrophysics Data System (ADS)

He, Guang S.; Yong, Ken-Tye; Zhu, Jing; Prasad, P. N.

2012-04-01

Highly directional backward stimulated scattering has been observed from large-size-gold nanorods suspended in water, pumped with ˜816 nm and ˜10 ns laser pulses. In comparison with other known stimulated scattering effects, the newly observed effect exhibits the following features. (i) The scattering centers are impurity particles with a size comparable in order of magnitude to the incident wavelength. (ii) There is no frequency shift between the pump wavelength and the stimulated scattering wavelength. (iii) The pump threshold can be significantly lower than that of stimulated Brillouin scattering in pure water. The nonfrequency shift can be explained by the formation of a standing-wave Bragg grating induced by the interference between the forward pump beam and the backward Mie-scattering beam. The low pump threshold results from stronger initial Mie-scattering (seed) signals and the intensity-dependent refractive-index change of the scattering medium enhanced by metallic nanoparticles.

Numerical study on a single-mode continuous-wave thermally guiding very-large-mode-area fiber amplifier

NASA Astrophysics Data System (ADS)

Cao, Jianqiu; Liu, Wenbo; Ying, Hanyuan; Chen, Jinbao; Lu, Qisheng

2018-03-01

The characteristics of a single-mode continuous-wave thermally guiding very-large-mode-area fiber amplifier are investigated numerically using the rate-equation model while taking thermal transfer into account. It is revealed that the seed power should play an important role in the fiber amplifier and should be large enough to ensure high output efficiency. The effects of three pumping schemes (i.e. the co-, counter- and bi-directional pumping schemes) and the initial refraction index difference are also studied. It is revealed that the optimum fiber length changes with the pumping scheme, and the initial refraction index difference should be lower than 10-4 in order to ensure the linear increment of the output signal power with the pump power. Furthermore, a brief comparison between the thermally induced waveguides in the fiber amplifiers for three pumping schemes is also made.

Excited state proton transfer in strongly enhanced GFP (sGFP2).

PubMed

van Oort, Bart; ter Veer, Mirelle J T; Groot, Marie Louise; van Stokkum, Ivo H M

2012-07-07

Proton transfer is an elementary process in biology. Green fluorescent protein (GFP) has served as an important model system to elucidate the mechanistic details of this reaction, because in GFP proton transfer can be induced by light absorption. We have used pump-dump-probe spectroscopy to study how proton transfer through the 'proton-wire' around the chromophore is affected by a combination of mutations in a modern GFP variety (sGFP2). The results indicate that in H(2)O, after absorption of a photon, a proton is transferred (A* → I*) in 5 ps, and back-transferred from a ground state intermediate (I → A) in 0.3 ns, similar to time constants found with GFPuv, although sGFP2 shows less heterogeneous proton transfer. This suggests that the mutations left the proton-transfer largely unchanged, indicating the robustness of the proton-wire. We used pump-dump-probe spectroscopy in combination with target analysis to probe suitability of the sGFP2 fluorophore for super-resolution microscopy.

Flame Characterization Using a Tunable Solid-State Laser with Direct UV Pumping

NASA Technical Reports Server (NTRS)

Kamal, Mohammed M.; Dubinskii, Mark A.; Misra, Prabhakar

1996-01-01

Tunable solid-state lasers with direct UV pumping, based on d-f transitions of rare earth ions incorporated in wide band-gap dielectric crystals, are reliable sources of laser radiation that are suitable for excitation of combustion-related free radicals. We have employed such a laser for analytical flame characterization utilizing Laser-Induced Fluorescence (LIF) techniques. LIF spectra of alkane-air flames (used for studying combustion processes under normal and microgravity conditions) excited in the region of the A-X (0,0) OH-absorption band have been recorded and found to be both temperature-sensitive and positionally-sensitive. In addition, also clearly noticeable was the sensitivity of the spectra to the specific wavelength used for data registration. The LiCAF:Ce laser shows good prospects for being able to cover the spectral region between 280 and 340 nm and therefore be used excitation of combustion-intermediates such as the hydroxyl OH, methoxy CH30 and methylthio CH3S radicals.

Enhanced spin pumping into superconductors provides evidence for superconducting pure spin currents

NASA Astrophysics Data System (ADS)

Jeon, Kun-Rok; Ciccarelli, Chiara; Ferguson, Andrew J.; Kurebayashi, Hidekazu; Cohen, Lesley F.; Montiel, Xavier; Eschrig, Matthias; Robinson, Jason W. A.; Blamire, Mark G.

2018-06-01

Unlike conventional spin-singlet Cooper pairs, spin-triplet pairs can carry spin1,2. Triplet supercurrents were discovered in Josephson junctions with metallic ferromagnet spacers, where spin transport can occur only within the ferromagnet and in conjunction with a charge current. Ferromagnetic resonance injects a pure spin current from a precessing ferromagnet into adjacent non-magnetic materials3,4. For spin-singlet pairing, the ferromagnetic resonance spin pumping efficiency decreases below the critical temperature (Tc) of a coupled superconductor5,6. Here we present ferromagnetic resonance experiments in which spin sink layers with strong spin-orbit coupling are added to the superconductor. Our results show that the induced spin currents, rather than being suppressed, are substantially larger in the superconducting state compared with the normal state; although further work is required to establish the details of the spin transport process, we show that this cannot be mediated by quasiparticles and is most likely a triplet pure spin supercurrent.

High-energy and ultra-wideband tunable terahertz source with DAST crystal via difference frequency generation

NASA Astrophysics Data System (ADS)

He, Yixin; Wang, Yuye; Xu, Degang; Nie, Meitong; Yan, Chao; Tang, Longhuang; Shi, Jia; Feng, Jiachen; Yan, Dexian; Liu, Hongxiang; Teng, Bing; Feng, Hua; Yao, Jianquan

2018-01-01

We have demonstrated a high-energy and broadly tunable monochromatic terahertz (THz) source based on difference frequency generation (DFG) in DAST crystal. A high-energy dual-wavelength optical parametric oscillator with two KTP crystals was constructed as a light source for DFG, where the effect of blue light was first observed accompanying with tunable dual-wavelength pump light due to different nonlinear processes. The THz frequency was tuned randomly in the range of 0.3-19.6 THz. The highest energy of 870 nJ/pulse was obtained at 18.9 THz under the intense pump intensity of 247 MW/cm2. The THz energy dips above 3 THz have been analyzed and mainly attributed to the resonance absorption induced by lattice vibration in DAST crystal. The dependence of THz output on the input energy was studied experimentally, and THz output saturation was observed. Furthermore, tests of transmission spectroscopy of four typical samples were demonstrated with this ultra-wideband THz source.

Individual dual-emitting CdS multi-branched nanowire arrays under various pumping powers

NASA Astrophysics Data System (ADS)

Guo, S.; Zhao, F. Y.; Li, Y.; Song, G. L.; Li, A.; Chai, K.; Liang, L.; Ma, Z.; Weller, D.; Liu, R. B.

2016-10-01

High-quality Tin doped Cadmium Sulfide (CdS) comb-like nanostructures have been synthesized by a simple in situ seeding chemical vapor deposition process. The color-tunable dual emission of these comb-like nanostructures is demonstrated by changing the excitation power intensity. In fact, the color-tunable emission is in principal due to the variation of the dual emission intensity, which is proven by photoluminescence spectra and real color photoluminescence charge-coupled device images. Especially for different parts in the nano comb, the emission color can be varied even under the same pumping power. This is mainly due to the difference in local structure. By comparison, the color variation was not observed in pure CdS multi-branched nanostructures. The lifetime results demonstrate that the green emission originate from the recombination of free excitons. The origin of red emission is from the recombination of the dopant-induced intrinsic or extrinsic defect states. These findings provide potential applications of laser assisted anti-counterfeit label and micro-size monitors.

Cryogenic hydrogen-induced air liquefaction technologies

NASA Technical Reports Server (NTRS)

Escher, William J. D.

1990-01-01

Extensively utilizing a special advanced airbreathing propulsion archives database, as well as direct contacts with individuals who were active in the field in previous years, a technical assessment of cryogenic hydrogen-induced air liquefaction, as a prospective onboard aerospace vehicle process, was performed and documented. The resulting assessment report is summarized. Technical findings are presented relating the status of air liquefaction technology, both as a singular technical area, and also that of a cluster of collateral technical areas including: compact lightweight cryogenic heat exchangers; heat exchanger atmospheric constituents fouling alleviation; para/ortho hydrogen shift conversion catalysts; hydrogen turbine expanders, cryogenic air compressors and liquid air pumps; hydrogen recycling using slush hydrogen as heat sink; liquid hydrogen/liquid air rocket-type combustion devices; air collection and enrichment systems (ACES); and technically related engine concepts.

Effect of the self-pumped limiter concept on the tritium fuel cycle

DOE Office of Scientific and Technical Information (OSTI.GOV)

Finn, P.A.; Sze, D.K.; Hassanein, A.

1988-01-01

The self-pumped limiter concept for impurity control of the plasma of a fusion reactor has a major impact on the design of the tritium systems. To achieve a sustained burn, conventional limiters and divertors remove large quantities of unburnt tritium and deuterium from the plasma which must be then recycled using a plasma processing system. The self-pumped limiter which does not remove the hydrogen species, does not require any plasma processing equipment. The blanket system and the coolant processing systems acquire greater importance with the use of this unconventional impurity control system. 3 refs., 2 figs.

Enhancement of high harmonics from plasmas using two-color pump and chirp variation of 1 kHz Ti:sapphire laser pulses.

PubMed

Ganeev, R A; Hutchison, C; Zaïr, A; Witting, T; Frank, F; Okell, W A; Tisch, J W G; Marangos, J P

2012-01-02

We have investigated resonance effects in high-order harmonic generation (HHG) within laser-produced plasmas. We demonstrate a significantly improved harmonic yield by using two-color pump-induced enhancement and a 1 kHz pulse repetition rate. Together with an increased HHG output, the even harmonics in the cutoff region were enhanced with respect to odd harmonics. We report the observation of a resonance-induced growth in intensity of 20th harmonic in silver plasma (2×), 26th harmonic in vanadium plasma (4×), and 28th harmonic in chromium plasma (5×).

Simulation of a long-term aquifer test conducted near the Rio Grande, Albuquerque, New Mexico

USGS Publications Warehouse

McAda, Douglas P.

2001-01-01

A long-term aquifer test was conducted near the Rio Grande in Albuquerque during January and February 1995 using 22 wells and piezometers at nine sites, with the City of Albuquerque Griegos 1 production well as the pumped well. Griegos 1 discharge averaged about 2,330 gallons per minute for 54.4 days. A three-dimensional finite-difference ground-water-flow model was used to estimate aquifer properties in the vicinity of the Griegos well field and the amount of infiltration induced into the aquifer system from the Rio Grande and riverside drains as a result of pumping during the test. The model was initially calibrated by trial-and-error adjustments of the aquifer properties. The model was recalibrated using a nonlinear least-squares regression technique. The aquifer system in the area includes the middle Tertiary to Quaternary Santa Fe Group and post-Santa Fe Group valley- and basin-fill deposits of the Albuquerque Basin. The Rio Grande and adjacent riverside drains are in hydraulic connection with the aquifer system. The hydraulic-conductivity values of the upper part of the Santa Fe Group resulting from the model calibrated by trial and error varied by zone in the model and ranged from 12 to 33 feet per day. The hydraulic conductivity of the inner-valley alluvium was 45 feet per day. The vertical to horizontal anisotropy ratio was 1:140. Specific storage was 4 x 10-6 per foot of aquifer thickness, and specific yield was 0.15 (dimensionless). The sum of squared errors between the observed and simulated drawdowns was 130 feet squared. Not all aquifer properties could be estimated using nonlinear regression because of model insensitivity to some aquifer properties at observation locations. Hydraulic conductivity of the inner-valley alluvium, middle part of the Santa Fe Group, and riverbed and riverside-drain bed and specific yield had low sensitivity values and therefore could not be estimated. Of the properties estimated, hydraulic conductivity of the upper part of the Santa Fe Group was estimated to be 12 feet per day, the vertical to horizontal anisotropy ratio was estimated to be 1:82, and specific storage was estimated to be 1.2 x 10-6 per foot of aquifer thickness. The overall sum of squared errors between the observed and simulated drawdowns was 87 feet squared, a significant improvement over the model calibrated by trial and error. At the end of aquifer-test pumping, induced infiltration from the Rio Grande and riverside drains was simulated to be 13 percent of the total amount of water pumped. The remainder was water removed from aquifer storage. After pumping stopped, induced infiltration continued to replenish aquifer storage. Simulations estimated that 5 years after pumping began (about 4.85 years after pumping stopped), 58 to 72 percent of the total amount of water pumped was replenished by induced infiltration from the Rio Grande surface-water system.

Towards an optofluidic pump?

NASA Astrophysics Data System (ADS)

Emile, Olivier; Emile, Janine

2016-12-01

Most of the vibrating mechanisms of optofluidic systems are based on local heating of membranes that induces liquid flow.We report here a new type of diaphragm pump in a liquid film based on the optical radiation pressure force. We modulate a low power laser that generates, at resonance, a symmetric vibration of a free standing soap film. The film lifetime strongly varies from 56 s at low power (2 mW) to 2 s at higher power (70 mW). Since the laser beam only acts mechanically on the interfaces, such a pump could be easily implemented on delicate microequipment on chips or in biological systems.

Glass-wool study of laser-induced spin currents en route to hyperpolarized Cs salt

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ishikawa, Kiyoshi

2011-07-15

The nuclear spin polarization of optically pumped Cs atoms flows to the surface of Cs hydride in a vapor cell. A fine glass wool lightly coated with the salt helps greatly increase the surface area in contact with the pumped atoms and enhance the spin polarization of the salt nuclei. Even though the glass wool randomly scatters the pump light, the atomic vapor can be polarized with unpolarized light in a magnetic field. The measured enhancement in the salt enables study of the polarizations of light and atomic nuclei very near the salt surface.

Time-resolved coherent Raman spectroscopy by high-speed pump-probe delay scanning.

PubMed

Domingue, S R; Winters, D G; Bartels, R A

2014-07-15

Using a spinning window pump-probe delay scanner, we demonstrate a means of acquiring time-resolved vibrational spectra at rates up to 700 Hz. The time-dependent phase shift accumulated by the probe pulse in the presence of a coherently vibrating sample gives rise to a Raman-induced frequency shifting readily detectable in a balanced detector. This rapid delay scanning system represents a 23-fold increase in averaging speed and is >10× faster than state-of-the-art voice coil delay lines. These advancements make pump-probe spectroscopy a more practical means of imaging complex media.

Measurements of Photo-induced Changes in Conjugated Polymers

DOE R&D Accomplishments Database

Seager, C. H.; Sinclair, M. B.; Mc Branch, D.; Heeger, A. J.; Baker, G. L.

1991-01-01

We have used the highly sensitive technique of Photothermal Deflection Spectroscopy (PDS) to measure changes in the infrared absorption spectra of MEHPPV, P3HT and Polydiacetylene-4BCMU induced by pumping these polymers with light above the {pi} - {pi}* transition energy. In contrast to previous chopped light transmission measurements of these effects, the PDS technique can directly measure the buildup or decay of the absorption coefficient, {alpha}, on the time scale of second to days. In the case of MEHPPV we observe that the time scale of seconds to days. In the case of MEHPPV we observe that above-gap light causes the appearance of a broad infrared peak in {alpha}, which continues to grow-in hours after the pump light is first applied. For this polymer the general shape of the absorption spectra in the unpumped state mimics the photo-induced changes, suggesting that remnant photo-induced states determine the maximum transparency observed under normal experimental conditions. For P3HT and to a lesser extent, MEHPPV, we also observe irreversible photo-induced absorption components which we tentatively identify with photo-induced oxidation of the polymer matrix.

Low hypoxia inducible factor-1α (HIF-1α) expression in testicular germ cell tumors - a major reason for enhanced chemosensitivity?

PubMed

Shenoy, Niraj; Dronca, Roxana; Quevedo, Fernando; Boorjian, Stephen A; Cheville, John; Costello, Brian; Kohli, Manish; Witzig, Thomas; Pagliaro, Lance

2017-08-01

The molecular basis for enhanced chemosensitivity of testicular germ cell tumors (GCT) has been an area of great interest, as it could potentially give us therapeutic leads in other resistant malignancies. Thus far, however, the increased sensitivity of GCT has been variously attributed to multiple factors - an inability to detoxify cisplatin, a lack of export pumps, an inability to repair the DNA damage, an intact apoptotic cascade and lack of p53 mutation; but a unifying underlying etiology leading to the aforementioned processes and having a translational implication has so far been elusive. Herein, we offer evidence to support a potential significant role for the previously demonstrated low hypoxia inducible factor-1α (HIF-1α) expression in mediating the general exquisite chemosensitivity of testicular GCT, through the aforementioned processes. This molecular mechanism based hypothesis could have a significant translational implication in platinum refractory GCT as well as other platinum resistant malignancies.

Synchronized Activity in The Main and Accessory Olfactory Bulbs and Vomeronasal Amygdala Elicited by Chemical Signals in Freely Behaving Mice.

PubMed

Pardo-Bellver, Cecília; Martínez-Bellver, Sergio; Martínez-García, Fernando; Lanuza, Enrique; Teruel-Martí, Vicent

2017-08-30

Chemosensory processing in mammals involves the olfactory and vomeronasal systems, but how the activity of both circuits is integrated is unknown. In our study, we recorded the electrophysiological activity in the olfactory bulbs and the vomeronasal amygdala in freely behaving mice exploring a battery of neutral and conspecific stimuli. The exploration of stimuli, including a neutral stimulus, induced synchronic activity in the olfactory bulbs characterized by a dominant theta rhythmicity, with specific theta-gamma coupling, distinguishing between vomeronasal and olfactory structures. The correlated activation of the bulbs suggests a coupling between the stimuli internalization in the nasal cavity and the vomeronasal pumping. In the amygdala, male stimuli are preferentially processed in the medial nucleus, whereas female cues induced a differential response in the posteromedial cortical amygdala. Thus, particular theta-gamma patterns in the olfactory network modulates the integration of chemosensory information in the amygdala, allowing the selection of an appropriate behaviour.

Distributed fiber optic sensor-enhanced detection and prediction of shrinkage-induced delamination of ultra-high-performance concrete overlay

NASA Astrophysics Data System (ADS)

Bao, Yi; Valipour, Mahdi; Meng, Weina; Khayat, Kamal H.; Chen, Genda

2017-08-01

This study develops a delamination detection system for smart ultra-high-performance concrete (UHPC) overlays using a fully distributed fiber optic sensor. Three 450 mm (length) × 200 mm (width) × 25 mm (thickness) UHPC overlays were cast over an existing 200 mm thick concrete substrate. The initiation and propagation of delamination due to early-age shrinkage of the UHPC overlay were detected as sudden increases and their extension in spatial distribution of shrinkage-induced strains measured from the sensor based on pulse pre-pump Brillouin optical time domain analysis. The distributed sensor is demonstrated effective in detecting delamination openings from microns to hundreds of microns. A three-dimensional finite element model with experimental material properties is proposed to understand the complete delamination process measured from the distributed sensor. The model is validated using the distributed sensor data. The finite element model with cohesive elements for the overlay-substrate interface can predict the complete delamination process.

Measurement of the differential pressure of liquid metals

DOEpatents

Metz, H.J.

1975-09-01

This patent relates to an improved means for measuring the differential pressure between any two points in a process liquid metal coolant loop, wherein the flow of liquid metal in a pipe is opposed by a permanent magnet liquid metal pump until there is almost zero flow shown by a magnetic type flowmeter. The pressure producing the liquid metal flow is inferred from the rate of rotation of the permanent magnet pump. In an alternate embodiment, a differential pressure transducer is coupled to a process pipeline by means of high-temperature bellows or diaphragm seals, and a permanent magnet liquid metal pump in the high-pressure transmission line to the pressure transducer can be utilized either for calibration of the transducer or for determining the process differential pressure as a function of the magnet pump speed. (auth)

Magnetron Sputtering System for Novel Intrinsically Switchable Thin Film Ferroelectric Resonators and Filters

DTIC Science & Technology

2012-08-03

the growth conditions and to improve film quality.    Mechanical  Scroll   Pump   The sputtering system requires a mechanical  scroll   pump  to bring the...load lock and main processing  chamber from atmospheric pressure to medium  vacuum . This particular type of  pump  does not expose  any part of the  vacuum ...additional  pump  to bring the main processing chamber from medium  vacuum  to ultrahigh  vacuum . Cryogenic  pumps  have no mechanical components and are

MC-1 LOX Pump Rotating Cavitation: Issue and Investigation

NASA Technical Reports Server (NTRS)

VanHooser, Katherine; Turner, J. (Technical Monitor)

2001-01-01

Leading edge tip deformation was noted on the LOX inducer from the component test unit at disassembly. The damage was in a location similar to a previous Fastrac water flow inducer failure. A team was formed to investigate the anomaly.

40 CFR Appendix B to Part 63 - Sources Defined for Early Reduction Provisions

Code of Federal Regulations, 2010 CFR

2010-07-01

.... All valves in gas or light liquid service within a process unit b. All pumps in light liquid service within a process unit c. All connectors in gas or light liquid service within a process unit d. Each...-ended valve or line i. Each sampling connection system j. Each instrumentation system k. Each pump...

Power and polarization dependences of ultra-narrow electromagnetically induced absorption (EIA) spectra of 85 Rb atoms in degenerate two-level system

NASA Astrophysics Data System (ADS)

Qureshi, Muhammad Mohsin; Rehman, Hafeez Ur; Noh, Heung-Ryoul; Kim, Jin-Tae

2016-05-01

We have investigated ultra-narrow EIA spectral features with respect to variations of polarizations and powers of pump laser beam in a degenerate two-level system of the transition of 85 Rb D2 transition line. Polarizations of the probe laser beam in two separate experiments were fixed at right circular and horizontal linear polarizations, respectively while the polarizations of the pump lasers were varied from initial polarizations same as the probe laser beams to orthogonal to probe polarizations. One homemade laser combined with AOMs was used to the pump and probe laser beams instead of two different lasers to overcome broad linewidths of the homemade lasers. Theoretically, probe absorption coefficients have been calculated from optical Bloch equations of the degenerate two level system prepared by a pump laser beam. In the case of the circular polarization, EIA signal was obtained as expected theoretically although both pump and probe beams have same polarization. The EIA signal become smaller as power increases and polarizations of the pump and probe beams were same. When the polarization of the pump beam was linear polarization, maximum EIA signal was obtained theoretically and experimentally. Experimental EIA spectral shapes with respect to variations of the pump beam polarization shows similar trends as the theoretical results.

Preserved function of the plasma membrane calcium pump of red blood cells from diabetic subjects with high levels of glycated haemoglobin.

PubMed

Bookchin, Robert M; Etzion, Zipora; Lew, Virgilio L; Tiffert, Teresa

2009-03-01

The activity of the plasma membrane Ca(2+)-pump decreases steeply throughout the 120 days lifespan of normal human red blood cells. Experiments with isolated membrane preparations showed that glycation of a lysine residue near the catalytic site of the pump ATPase had a powerful inhibitory effect. This prompted the question of whether glycation is the mechanism of age-related decline in pump activity in vivo. It is important to investigate this mechanism because the Ca(2+) pump is a major regulator of Ca(2+) homeostasis in all cells. Its impaired activity in diabetic patients, continuously exposed to high glycation rates, may thus contribute to varied tissue pathology in this disease. We measured Ca(2+)-pump activity as a function of red cell age in red cells from diabetics continuously exposed to high glucose concentrations, as documented by their high mean levels of glycated haemoglobin. The distribution of Ca(2+)-pump activities was indistinguishable from that in non-diabetics, and the pattern of activity decline with cell age in the diabetics' red cells was identical to that observed in red cells from non-diabetics. These results indicate that in intact cells the Ca(2+) pump is protected from glycation-induced inactivation.

Rigorous theory of molecular orientational nonlinear optics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kwak, Chong Hoon, E-mail: chkwak@ynu.ac.kr; Kim, Gun Yeup

2015-01-15

Classical statistical mechanics of the molecular optics theory proposed by Buckingham [A. D. Buckingham and J. A. Pople, Proc. Phys. Soc. A 68, 905 (1955)] has been extended to describe the field induced molecular orientational polarization effects on nonlinear optics. In this paper, we present the generalized molecular orientational nonlinear optical processes (MONLO) through the calculation of the classical orientational averaging using the Boltzmann type time-averaged orientational interaction energy in the randomly oriented molecular system under the influence of applied electric fields. The focal points of the calculation are (1) the derivation of rigorous tensorial components of the effective molecularmore » hyperpolarizabilities, (2) the molecular orientational polarizations and the electronic polarizations including the well-known third-order dc polarization, dc electric field induced Kerr effect (dc Kerr effect), optical Kerr effect (OKE), dc electric field induced second harmonic generation (EFISH), degenerate four wave mixing (DFWM) and third harmonic generation (THG). We also present some of the new predictive MONLO processes. For second-order MONLO, second-order optical rectification (SOR), Pockels effect and difference frequency generation (DFG) are described in terms of the anisotropic coefficients of first hyperpolarizability. And, for third-order MONLO, third-order optical rectification (TOR), dc electric field induced difference frequency generation (EFIDFG) and pump-probe transmission are presented.« less

Modified stimulated Raman scattering of a laser induced by trapped electrons in a plasma

NASA Astrophysics Data System (ADS)

Baliyan, Sweta; Rafat, Mohd.; Ahmad, Nafis; Sajal, Vivek

2017-10-01

The plasma wave, generated in stimulated Raman scattering process by an intense laser in the plasmas, traps a significant number of electrons in its potential energy minima. These electrons travel with the phase velocity of plasma wave and oscillate with bounce frequency. When the bounce frequency of electrons becomes equal to the growth rate of Raman process, resonance takes place. Now, Raman scattering gets modified by parametrically exciting a trapped electron mode and an electromagnetic sideband. The ponderomotive force due to the pump and sideband drives the plasma wave, whereas the density perturbation due to the trapped electron mode couples with the oscillating velocity of electrons due to the laser to produce a nonlinear current, driving the sideband.

Laser-induced breakup of helium 3S 1s2s with intermediate doubly excited states

NASA Astrophysics Data System (ADS)

Simonsen, A. S.; Bachau, H.; Førre, M.

2014-02-01

Solving the time-dependent Schrödinger equation in full dimensionality for two electrons, it is found that in the XUV regime the two-photon double ionization dynamics of He(1s2s) is predominantly dictated by the process of resonance enhanced multiphoton ionization via doubly excited states (DESs). We have studied a pump-probe scenario where the full laser-driven breakup of the 3S 1s2s metastable state is dominated by intermediate quasiresonant excitation to doubly excited (autoionizing) states in the 3Po series. Clear evidence of multipath interference effects is revealed in the resulting angular distributions of the ejected electrons in cases where more than one intermediate DES is populated in the process.

Ballistic induced pumping of hypersonic heat current in DNA nano wire

NASA Astrophysics Data System (ADS)

Behnia, Sohrab; Panahinia, Robabe

2016-12-01

Heat shuttling properties of DNA nano-wire driven by an external force against the spontaneous heat current direction in non-zero temperature bias (non averaged) have been studied. We examined the valid region of driving amplitude and frequency to have pumping state in terms of temperature bias and the system size. It was shown that DNA could act as a high efficiency thermal pump in the hypersonic region. Amplitude-dependent resonance frequencies of DNA indicating intrinsic base pair internal vibrations have been detected. Nonlinearity implies that by increasing the driven amplitude new vibration modes are detected. To verify the results, an analytical parallel investigation based on multifractal concept has been done. By using the geometric properties of the strange attractor of the system, the threshold value to transition to the pumping state for given external amplitude has been identified. It was shown that the system undergoes a phase transition in sliding point to the pumping state. Fractal dimension demonstrates that the ballistic transport is responsible for energy pumping in the system. In the forbidden band gap, DNA could transmit the energy by exceeding the threshold amplitude. Despite of success in energy pumping, in this framework, DNA could not act as a real cooler.

Optimizing the longitudinal and transverse electroosmotic pumping in a rectangular channel with horizontal baffle plates

NASA Astrophysics Data System (ADS)

Lai, Anison K. R.; Chang, Chien-Cheng; Wang, Chang-Yi

2018-04-01

This paper presents a continued study to our previous work on electroosmotic (EO) flow in a channel with vertical baffle plates by further investigating EO flow through an array of baffle plates arranged in parallel to the channel walls. The flow may be driven either in the direction along or in the direction transverse to the plates, thus distinguishing the longitudinal EO pumping (LEOP) and the transverse EO pumping (TEOP). In both types of EO pumping, it is more interesting to examine the cases when the baffle plates develop a higher zeta potential (denoted by α) than that on the channel walls (β). This semi-analytical study enables us to compare between LEOP and TEOP in the pumping efficiency under similar conditions. The TEOP case is more difficult to solve due to the higher order governing partial differential equations caused by the induced non-uniform pressure gradient distribution. In particular, we examine how the EO pumping rates deviate from those predicted by the Helmholtz-Smoluchowski velocity and illustrate the general trend of optimizing the EO pumping rates with respect to the physical and geometric parameters involved.

Simulated effects of Lower Floridan aquifer pumping on the Upper Floridan aquifer at Pooler, Chatham County, Georgia

USGS Publications Warehouse

Cherry, Gregory S.; Clarke, John S.

2013-01-01

A revised regional groundwater-flow model was used to assess the potential effects on the Upper Floridan aquifer (UFA) of pumping the Lower Floridan aquifer (LFA) from a new well (35Q069) located at the City of Pooler in coastal Georgia near Savannah. The spatial resolution of the original regional, steady-state, groundwater-flow model was increased to incorporate detailed hydrogeologic information resulting from field investigations at Pooler and existing wells in the area. Simulation results using the U.S. Geological Survey finite-difference code MODFLOW indicated that long-term pumping at a rate of 780 gallons per minute (gal/min) from the LFA well 35Q069 would cause a maximum drawdown of about 2.52 feet (ft) in the UFA (scenario A). This maximum drawdown in the UFA was greater than the observed draw-down of 0.9 ft in the 72-hour aquifer test, but this is expected because the steady-state simulated drawdown represents long-term pumping conditions. Model results for scenario A indicate that drawdown in the UFA exceeded 1 ft over a 163-square-mile (mi2) area. Induced vertical leakage from the UFA provided about 98 percent of the water to the LFA; the area within 1 mile of the pumped well contributed about 81 percent of the water pumped. Simulated pumping changed regional water-budget components slightly and redistributed flow among model layers, namely increasing downward leakage in all layers, decreasing upward leakage in all layers above the LFA, increasing inflow to and decreasing outflow from lateral specified-head boundaries in the UA and LFA, and increasing the volume of induced recharge from the general head boundary to outcrop units. An additional two groundwater-pumping scenarios were run to establish that a linear relation exists between pumping rates of the LFA well 35Q069 (varied from 390 to 1,042 gal/min) and amount of drawdown in the UFA and LFA. Three groundwater-pumping scenarios were run to evaluate the amount of UFA pumping (128 to 340 gal/min) that would produce maximum drawdown in the UFA equivalent to that induced by pumping the LFA well 35Q069 at rates specified in scenarios A, B, and C (390 to 1,042 gal/min). Scenarios in which the LFA well 35Q069 was pumped produced a larger drawdown area in the UFA than scenarios in which the UFA well was pumped to offset the maximum UFA drawdown simulated by scenarios A, B, and C. Three additional groundwater-pumping scenarios were run to evaluate the combination of pumping reductions at existing Pooler UFA public-supply wells with the addition of pumping from the new LFA well. For each scenario, LFA well 35Q069 was pumped at different rates, and pumping at existing Pooler supply wells, located about 3.7 miles northward, was reduced according to UFA drawdown offsets (128 to 340 gal/min) established by scenarios D, E, and F. Decreases in the magnitude and areal extent of drawdown in the UFA in response to pumping the LFA well were realized for scenarios that simulated drawdown offsets (reductions) for the existing UFA wells at Pooler when compared with the magnitude and extent of drawdown resulting from scenarios that did not simulate drawdown offsets for the existing UFA wells at Pooler (scenarios A, B, and C). The revised model was evaluated for sensitivity by altering horizontal and vertical hydraulic conductivity in layers 5 through 7 (Floridan aquifer system) for newly established hydraulic-property zones by factors of 0.1, 0.5, 2.0, and 10.0. Results of the sensitivity analysis indicate that horizontal and vertical hydraulic conductivity of the UFA and LFA are the most important parameters in model simulations. The least sensitive parameters were the horizontal and vertical hydraulic conductivity of the Lower Floridan confining unit; changes to these parameters had little effect on simulated leakage and groundwater levels. The revised model reasonably depicts changes in groundwater levels resulting from pumping the LFA at Pooler at a rate of 780 gal/min. However, results are limited by the same model assumptions and design as the original model and placement of boundaries and type of boundary used exert the greatest control on overall groundwater flow and interaquifer leakage in the system. Simulation results have improved regional characterization of the Floridan aquifer system, which could be used by State officials in evaluating requests for groundwater withdrawal from the LFA.

Functional reconstitution of Arabidopsis thaliana plant uncoupling mitochondrial protein (AtPUMP1) expressed in Escherichia coli.

PubMed

Borecký, J; Maia, I G; Costa, A D; Jezek, P; Chaimovich, H; de Andrade, P B; Vercesi, A E; Arruda, P

2001-09-14

The Arabidopsis thaliana uncoupling protein (UCP) gene was expressed in Escherichia coli and isolated protein reconstituted into liposomes. Linoleic acid-induced H+ fluxes were sensitive to purine nucleotide inhibition with an apparent K(i) (in mM) of 0.8 (GDP), 0.85 (ATP), 0.98 (GTP), and 1.41 (ADP); the inhibition was pH-dependent. Kinetics of AtPUMP1-mediated H+ fluxes were determined for lauric, myristic, palmitic, oleic, linoleic, and linolenic acids. Properties of recombinant AtPUMP1 indicate that it represents a plant counterpart of animal UCP2 or UCP3. This work brings the functional and genetic approaches together for the first time, providing strong support that AtPUMP1 is truly an UCP.

NONLINEAR AND FIBER OPTICS: Mutual suppression of the electron stimulated Raman scattering and four-wave parametric mixing

NASA Astrophysics Data System (ADS)

Malakyan, Yu P.

1990-04-01

A new effect is considered: self-induced suppression of electron stimulated Raman scattering involving generation of two new fields from the Stokes radiation as a result of four-wave mixing, interfering destructively with electron stimulated Raman scattering and suppressing it, which in turn suppresses the mixing process. The effect occurs in the steady-state case and not under transient conditions. The results account in a simple manner for the generation of the Stokes radiation in barium vapor as a result of different transitions, depending on the duration of the pump pulse.

Modulation of ouabain binding and potassium pump fluxes by cellular sodium and potassium in human and sheep erythrocytes.

PubMed Central

Joiner, C H; Lauf, P K

1978-01-01

1. Erythrocytes were treated with nystatin to alter internal Na (Nai) and K (Ki) composition. Although the rates of K pumping and [3H]ouabain binding were altered dramatically, the relationship between glycoside binding and K pump inhibition was unaffected. 2. Human cells with high Nai and low Ki exhibited an increased rate of ouabain binding as compared to high Ki, low Nai cells; this paralleled the stimulated K pump activity of high Nai cells. 3. At constant Ki, increasing internal Na stimulated K pump and ouabain binding rates concomitantly. 4. At low Nai, increasing Ki inhibited both K pumping and ouabain binding. However, at high Nai, increasing Ki from 4 to 44 mM stimulated the rate of glycoside binding, parallel to its effect of increasing the rate of active K influx. 5. Anti-L, an isoantibody to low K (LK) sheep red cells, increased the rate of ouabain binding via its stimulation of K pump turnover. Since the latter effect is the result of affinity changes at the internal cation activation site(s) of the pump (Lauf, Rasmusen, Hoffman, Dunham, Cook, Parmelee & Tosteson, 1970), the antibody's effect on ouabain binding reflected the positive correlation between the rates of K pump turnover and glycoside binding. 6. These data provide the first evidence in intact cells for the occurrence of a Nai-induced conformational change in the Na/K pump during its normal operational cycle. PMID:722574

Influence of a thin veneer of low-hydraulic-conductivity sediment on modelled exchange between river water and groundwater in response to induced infiltration

USGS Publications Warehouse

Rosenberry, Donald O.; Healy, Richard W.

2012-01-01

A thin layer of fine-grained sediment commonly is deposited at the sediment–water interface of streams and rivers during low-flow conditions, and may hinder exchange at the sediment–water interface similar to that observed at many riverbank-filtration (RBF) sites. Results from a numerical groundwater-flow model indicate that a low-permeability veneer reduces the contribution of river water to a pumping well in a riparian aquifer to various degrees, depending on simulated hydraulic gradients, hydrogeological properties, and pumping conditions. Seepage of river water is reduced by 5–10% when a 2-cm thick, low-permeability veneer is present on the bed surface. Increasing thickness of the low-permeability layer to 0·1 m has little effect on distribution of seepage or percentage contribution from the river to the pumping well. A three-orders-of-magnitude reduction in hydraulic conductivity of the veneer is required to reduce seepage from the river to the extent typically associated with clogging at RBF sites. This degree of reduction is much larger than field-measured values that were on the order of a factor of 20–25. Over 90% of seepage occurs within 12 m of the shoreline closest to the pumping well for most simulations. Virtually no seepage occurs through the thalweg near the shoreline opposite the pumping well, although no low-permeability sediment was simulated for the thalweg. These results are relevant to natural settings that favour formation of a substantial, low-permeability sediment veneer, as well as central-pivot irrigation systems, and municipal water supplies where river seepage is induced via pumping wells

First observation of the anomalous electric field in the topside ionosphere by ionospheric modification over EISCAT

NASA Astrophysics Data System (ADS)

Kosch, M. J.; Vickers, H.; Ogawa, Y.; Senior, A.; Blagoveshchenskaya, N.

2014-11-01

We have developed an active ground-based technique to estimate the steady state field-aligned anomalous electric field (E*) in the topside ionosphere, up to ~600 km, using the European Incoherent Scatter (EISCAT) ionospheric modification facility and UHF incoherent scatter radar. When pumping the ionosphere with high-power high-frequency radio waves, the F region electron temperature is significantly raised, increasing the plasma pressure gradient in the topside ionosphere, resulting in ion upflow along the magnetic field line. We estimate E* using a modified ion momentum equation and the Mass Spectrometer Incoherent Scatter model. From an experiment on 23 October 2013, E* points downward with an average amplitude of ~1.6 μV/m, becoming weaker at higher altitudes. The mechanism for anomalous resistivity is thought to be low-frequency ion acoustic waves generated by the pump-induced flux of suprathermal electrons. These high-energy electrons are produced near the pump wave reflection altitude by plasma resonance and also result in observed artificially induced optical emissions.

Development of a compact vertical-cavity surface-emitting laser end-pumped actively Q-switched laser for laser-induced breakdown spectroscopy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Shuo; Chen, Rongzhang; Nelsen, Bryan

2016-03-15

This paper reports the development of a compact and portable actively Q-switched Nd:YAG laser and its applications in laser-induced breakdown spectroscopy (LIBS). The laser was end-pumped by a vertical-cavity surface-emitting laser (VCSEL). The cavity lases at a wavelength of 1064 nm and produced pulses of 16 ns with a maximum pulse energy of 12.9 mJ. The laser exhibits a reliable performance in terms of pulse-to-pulse stability and timing jitter. The LIBS experiments were carried out using this laser on NIST standard alloy samples. Shot-to-shot LIBS signal stability, crater profile, time evolution of emission spectra, plasma electron density and temperature, andmore » limits of detection were studied and reported in this paper. The test results demonstrate that the VCSEL-pumped solid-state laser is an effective and compact laser tool for laser remote sensing applications.« less

Hydraulic tests in highly permeable aquifers

NASA Astrophysics Data System (ADS)

Butler, James J.; Zhan, Xiaoyong

2004-12-01

A semianalytical solution is presented for a mathematical model describing the flow of groundwater in response to a slug or pumping test in a highly permeable, confined aquifer. This solution, which is appropriate for wells of any degree of penetration and incorporates inertial mechanisms at both the test and observation wells, can be used to gain new insights into hydraulic tests in highly permeable settings. The oscillatory character of slug- and pumping-induced responses will vary considerably across a site, even in an essentially homogeneous formation, when wells of different radii, depths, and screen lengths are used. Thus variations in the oscillatory character of responses do not necessarily indicate variations in hydraulic conductivity (K). Existing models for slug tests in partially penetrating wells in high-K aquifers neglect the storage properties of the media. That assumption, however, appears reasonable for a wide range of common conditions. Unlike in less permeable formations, drawdown at an observation well in a high-K aquifer will be affected by head losses in the pumping well. Those losses, which affect the form of the pumping-induced oscillations, can be difficult to characterize. Thus analyses of observation-well drawdown should utilize data from the period after the oscillations have dissipated whenever possible. Although inertial mechanisms can have a large impact on early-time drawdown, that impact decreases rapidly with duration of pumping and distance to the observation well. Conventional methods that do not consider inertial mechanisms should therefore be viable options for the analysis of drawdown data at moderate to large times.

Surface deformation induced by water pumping for construction of Mass Rapid Transportation in Taipei basin

NASA Astrophysics Data System (ADS)

Hu, J. C.; Wu, P. C.; Tung, H.; Tsai, M. C.

2017-12-01

In 1968, there were 2,200 wells in the Taipei Basin used for water supply to meet the requirement of high population density. The overuse of ground water lead to the land subsidence rate up to 5 cm/yr. Although the government had already begun to limit groundwater pumping since 1968, the groundwater in the Taipei Basin demonstrated temporary fluctuation induced by pumping water for large deep excavation site or engineering usage. The previous study based on precise leveling suggested that the surface deformation was highly associated with the recovery of water level. In 1989, widespread uplift dominated in Taipei basin due to the recovery of ground water Table. In this study, we use 37 high-resolution X-band COSMO-SkyMed radar images from May 2011 to April 2015 to characterize deformation pattern in the period of construction of Mass Rapid Transportation (MRT). We also use 30 wells and 380 benchmarks of precise leveling in Taipei basin to study the correlation of surface deformation and change of ground water table. The storability is roughly constant across most of the aquifer with values between 0.8 x 10-4 and 1.3 x 10-3. Moreover, the high water pumping in two major aquifers, Jignme and Wuku Foramtions, before the underground construction for MRT led to inflict surface deformation and no time delay observed for surface deformation during the water pumping. It implies that the poro-elastic effect dominates in major aquifers in Taipei basin.

A study of pump cavitation damage

NASA Astrophysics Data System (ADS)

Brophy, M. C.; Stinebring, D. R.; Billet, M. L.

1983-11-01

The cavitation assessment for the space shuttle main engine high pressure oxidizer turbopump is documented. A model of the flow through the pump was developed. Initially, a computational procedure was used to analyze the flow through the inlet casing including the prediction of wakes downstream of the casing vanes. From these flow calculations, cavitation patterns on the inducer blades were approximated and the damage rate estimated. The model correlates the heavy damage on the housing and over the inducer with unsteady blade surface cavitation. The unsteady blade surface cavitation is due to the large incidence changes caused by the wakes of the upstream vanes. Very high cavitation damage rates are associated with this type of cavitation. Design recommendations for reducing the unsteady cavitation include removing the set of vanes closest to the inducer and modifying the remaining vanes.

Using Self Potential and Multiphase Flow Modeling to Optimize Groundwater Pumping

NASA Astrophysics Data System (ADS)

Gasperikova, E.; Zhang, Y.; Hubbard, S.

2008-12-01

Numerical and field hydrological and geophysical studies have been conducted to investigate the impact of groundwater pumping on near-river hydrology for a segment of the Russian River at the Wohler Site, California, which is a riverbed filtration system managed by the Sonoma County Water Agency. Groundwater pumping near streams can cause a creation of unsaturated regions and hence reduce the pumping capacity and change the flow paths. A three-dimensional multiphase flow and transport model can be calibrated to the temperature, and water levels at monitoring wells based on known pumping rates, and the river stage. Streaming (self) potential (SP) is one of the electrokinetic processes that describes the coupled behavior of hydraulic and electrical flow within a porous medium, and is easily measured on the surface or in boreholes. Observing temporal and spatial variations in geophysical signatures provides a powerful approach for monitoring changes in the natural systems due to natural or forced (pumping) system perturbations. Geophysical and hydrological data were collected before, during and after a pumping experiment at the Wohler Site. Using this monitoring dataset, we illustrate how loose coupling between hydrogeological and geophysical (SP) processes and data can be used to calibrate the flow model and to optimize pumping schedules as needed to guide sustainable water resource development.

Embryogenic competence acquisition in sugarcane callus is associated with differential H+ pump abundance and activity.

PubMed

Passamani, Lucas Z; Bertolazi, Amanda A; Ramos, Alessandro C; Santa-Catarina, Claudete; Thelen, Jay J; Silveira, Vanildo

2018-06-22

Somatic embryogenesis is an important biological process in several plant species, including sugarcane. Proteomics approaches have shown that H + pumps are differentially regulated during somatic embryogenesis; however, the relationship between H + flux and embryogenic competence is still unclear. This work aimed to elucidate the association between extracellular H + flux and somatic embryo maturation in sugarcane. We performed a microsomal proteomics analysis and analyzed changes in extracellular H + flux and H + pump (P-H + -ATPase, V-H + -ATPase and H + -PPase) activity in embryogenic and non-embryogenic callus. A total of 657 proteins were identified, 16 of which were H + pumps. We observed that P-H + -ATPase and H + -PPase were more abundant in embryogenic callus. Compared with non-embryogenic callus, embryogenic callus showed higher H + influx, especially on maturation day 14, as well as higher H+ pump activity (mainly P-H+-ATPase and H+-PPase activity). H+-PPase appears to be the major H + pump in embryogenic callus during somatic embryo formation, functioning in both vacuole acidification and PPi homeostasis. These results provide evidence for an association between higher H + pump protein abundance and, consequently, higher H + flux and embryogenic competence acquisition in the callus of sugarcane, allowing for optimization of the somatic embryo conversion process by modulating the activities of these H + pumps.

Mid-infrared optical parametric oscillator pumped by an amplified random fiber laser

NASA Astrophysics Data System (ADS)

Shang, Yaping; Shen, Meili; Wang, Peng; Li, Xiao; Xu, Xiaojun

2017-01-01

Recently, the concept of random fiber lasers has attracted a great deal of attention for its feature to generate incoherent light without a traditional laser resonator, which is free of mode competition and insure the stationary narrow-band continuous modeless spectrum. In this Letter, we reported the first, to the best of our knowledge, optical parametric oscillator (OPO) pumped by an amplified 1070 nm random fiber laser (RFL), in order to generate stationary mid-infrared (mid-IR) laser. The experiment realized a watt-level laser output in the mid-IR range and operated relatively stable. The use of the RFL seed source allowed us to take advantage of its respective stable time-domain characteristics. The beam profile, spectrum and time-domain properties of the signal light were measured to analyze the process of frequency down-conversion process under this new pumping condition. The results suggested that the near-infrared (near-IR) signal light `inherited' good beam performances from the pump light. Those would be benefit for further develop about optical parametric process based on different pumping circumstances.

Qualitative analysis of anatomopathological changes of gastric mucosa due to long term therapy with proton pump inhibitors: experimental studies x clinical studies.

PubMed

de Souza, Iure Kalinine Ferraz; da Silva, Alcino Lázaro; de Araújo, Alex; Santos, Fernanda Carolina Barbosa; Mendonça, Bernardo Pinto Coelho Keuffer

2013-01-01

For a few decades the long-term use of proton pump inhibitors has had wide application in the treatment of several gastrointestinal diseases. Since then, however, several studies have called attention to the possible development of anatomical and pathological changes of gastric mucosa, resulting from the long term use of this therapeutic modality. Recent experimental and clinical studies suggest that these changes have connection not only to the development of precancerous lesions, but also of gastric tumors. To present a qualitative analysis of anatomical and pathological changes of gastric mucosa resulting from the long-term use of proton pump inhibitors. The headings used were: proton pump inhibitors, precancerous lesions and gastric neoplasms for a non systematic review of the literature, based on Medline, Lillacs and Scielo. Twelve articles were selected from clinical (9) and experimental (3) studies, for qualitative analysis of the results. The gastric acid suppression by high doses of proton pump inhibitors induces hypergastrinemia and the consequent emergence of neuroendocrine tumors in animal models. Morphological changes most often found in these experimental studies were: enterochromaffin-like cell hyperplasia, neuroendocrine tumor, atrophy, metaplasia and adenocarcinoma. In the studies in humans, however, despite enterochromaffin-like cell hyperplasia, the other effects, neuroendocrine tumor and gastric atrophy, gastric metaplasia and or adenocarcinoma, were not identified. Although it is not possible to say that the long-term treatment with proton pump inhibitors induces the appearance or accelerates the development of gastric cancer in humans, several authors have suggested that prolonged administration of this drug could provoke the development of gastric cancer. Thus, the evidence demonstrated in the animal model as well as the large number of patients who do or will do a long-term treatment with proton pump inhibitors, justifies the maintenance of this important line of research.

Two-photon absorption induced stimulated Rayleigh-Bragg scattering

NASA Astrophysics Data System (ADS)

He, Guang S.; Prasad, Paras N.

2005-01-01

A frequency-unshifted and backward stimulated scattering can be efficiently generated in one-photon-absorption free but two-photon absorbing materials. Using a number of novel two-photon absorbing dye solutions as the scattering media and nanosecond pulsed laser as the pump beams, a highly directional backward stimulated scattering at the exact pump wavelength can be readily observed once the pump intensity is higher than a certain threshold level. The spectral and spatial structures as well as the temporal behavior and optical phase-conjugation property of this new type of backward stimulated scattering have been experimentally studied. This stimulated scattering phenomenon can be explained by using a model of two-photon-excitation enhanced standing-wave Bragg grating initially formed by the strong forward pump beam and much weaker backward Rayleigh scattering beam; the partial reflection of the pump beam from this grating provides an positive feedback to the initial backward Rayleigh scattering beam without suffering linear attenuation influence. Comparing to other known stimulated (Raman, Brillouin, Rayleigh-wing, and Kerr) scattering effects, the stimulated Rayleigh-Bragg scattering exhibits the advantages of no frequency-shift, low pump threshold, and low spectral linewidth requirement.

Characterization of a membrane-based, electrochemically driven pumping system using aqueous electrolyte solutions.

PubMed

Norman, Mya A; Evans, Christine E; Fuoco, Anthony R; Noble, Richard D; Koval, Carl A

2005-10-01

Electrokinetic flow provides a mechanism for a variety of fluid pumping schemes. The design and characterization of an electrochemically driven pump that utilizes porous carbon electrodes, iodide/triiodide redox electrolytes, and Nafion membranes is described. Fluid pumping by the cell is reversible and controlled by the cell current. Chronopotentiometry experiments indicate that the total available fluid that can be pumped in a single electrolysis without gas evolution is determined solely by the initial concentration of electrolyte and the applied current. The magnitude of the fluid flow at a given current is determined by the nature of the cation in the electrolyte and by the water absorption properties of the Nafion membrane. For 1 M aqueous electrolytes, pumping rates ranging from 1 to 14 microL/min were obtained for current densities of 10-30 mA/cm2 of membrane area. Molar volume changes for the I3-/I- redox couple and for the alkali cation migration contribute little to the observed volumetric flow rates; the magnitude of the flow is dominated by the migration-induced flow of water.

Detecting drawdowns masked by environmental stresses with water-level models

USGS Publications Warehouse

Garcia, C.A.; Halford, K.J.; Fenelon, J.M.

2013-01-01

Detecting and quantifying small drawdown at observation wells distant from the pumping well greatly expands the characterized aquifer volume. However, this detection is often obscured by water level fluctuations such as barometric and tidal effects. A reliable analytical approach for distinguishing drawdown from nonpumping water-level fluctuations is presented and tested here. Drawdown is distinguished by analytically simulating all pumping and nonpumping water-level stresses simultaneously during the period of record. Pumping signals are generated with Theis models, where the pumping schedule is translated into water-level change with the Theis solution. This approach closely matched drawdowns simulated with a complex three-dimensional, hypothetical model and reasonably estimated drawdowns from an aquifer test conducted in a complex hydrogeologic system. Pumping-induced changes generated with a numerical model and analytical Theis model agreed (RMS as low as 0.007 m) in cases where pumping signals traveled more than 1 km across confining units and fault structures. Maximum drawdowns of about 0.05 m were analytically estimated from field investigations where environmental fluctuations approached 0.2 m during the analysis period.

Appendix to HDC 2118 design criteria 100-X reactor water plant, general description - section II

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1952-03-29

The factors responsible for the advances of 100-X compared with the older areas are: Simplification of the process, such as elimination of separate process water clearwells, by having the filtered water reservoirs perform that function. Combination of separate buildings into one building, such as combining filter pump house and process pump house. Use of electric standby. Use of higher capacity pumps and filter basins, and so fewer number of units. Centralization of control and operation. More compact arrangement of plant components. Use of waste heat for space heating, recovered from reactor effluent, backed up by steam plant.

Strong and Long Makes Short: Strong-Pump Strong-Probe Spectroscopy.

PubMed

Gelin, Maxim F; Egorova, Dassia; Domcke, Wolfgang

2011-01-20

We propose a new time-domain spectroscopic technique that is based on strong pump and probe pulses. The strong-pump strong-probe (SPSP) technique provides temporal resolution that is not limited by the durations of the pump and probe pulses. By numerically exact simulations of SPSP signals for a multilevel vibronic model, we show that the SPSP signals exhibit electronic and vibrational beatings on time scales which are significantly shorter than the pulse durations. This suggests the possible application of SPSP spectroscopy for the real-time investigation of molecular processes that cannot be temporally resolved by pump-probe spectroscopy with weak pump and probe pulses.

Phosphate-core silica-clad Er/Yb-doped optical fiber and cladding pumped laser.

PubMed

Egorova, O N; Semjonov, S L; Velmiskin, V V; Yatsenko, Yu P; Sverchkov, S E; Galagan, B I; Denker, B I; Dianov, E M

2014-04-07

We present a composite optical fiber with a Er/Yb co-doped phosphate-glass core in a silica glass cladding as well as cladding pumped laser. The fabrication process, optical properties, and lasing parameters are described. The slope efficiency under 980 nm cladding pumping reached 39% with respect to the absorbed pump power and 28% with respect to the coupled pump power. Due to high doping level of the phosphate core optimal length was several times shorter than that of silica core fibers.

A Case Study of Two NRL Pump Prototypes

DTIC Science & Technology

1996-01-01

n messages messages ACK Pump Low High ACK MA buffer Figure 1. The simpli ed Pump architecture The Pump (see...I C A T I O N S Y S T E M S E R VICES Application Soft wa re Figure 4. STOP security ring structure The security kernel provides basic system...A D Y PUMP_TIMEOUT M O V _ A V G RECORD_AVAILABLE Ack A c k Ac k or N ac k Ack or Nack Legend IPC msg FIFO msg Data msg Process Object FIFO

Spectral Interferometry with Electron Microscopes

PubMed Central

Talebi, Nahid

2016-01-01

Interference patterns are not only a defining characteristic of waves, but also have several applications; characterization of coherent processes and holography. Spatial holography with electron waves, has paved the way towards space-resolved characterization of magnetic domains and electrostatic potentials with angstrom spatial resolution. Another impetus in electron microscopy has been introduced by ultrafast electron microscopy which uses pulses of sub-picosecond durations for probing a laser induced excitation of the sample. However, attosecond temporal resolution has not yet been reported, merely due to the statistical distribution of arrival times of electrons at the sample, with respect to the laser time reference. This is however, the very time resolution which will be needed for performing time-frequency analysis. These difficulties are addressed here by proposing a new methodology to improve the synchronization between electron and optical excitations through introducing an efficient electron-driven photon source. We use focused transition radiation of the electron as a pump for the sample. Due to the nature of transition radiation, the process is coherent. This technique allows us to perform spectral interferometry with electron microscopes, with applications in retrieving the phase of electron-induced polarizations and reconstructing dynamics of the induced vector potential. PMID:27649932

Efficient non-linear two-photon effects from the Cesium 6D manifold

NASA Astrophysics Data System (ADS)

Haluska, Nathan D.; Perram, Glen P.; Rice, Christopher A.

2018-02-01

We report several non-linear process that occur when two-photon pumping the cesium 6D states. Cesium vapor possess some of the largest two-photon pump cross sections in nature. Pumping these cross sections leads to strong amplified spontaneous emission that we observe on over 17 lasing lines. These new fields are strong enough to couple with the pump to create additional tunable lines. We use a heat pipe with cesium densities of 1014 to 1016 cm-3 and 0 to 5 Torr of helium buffer gas. The cesium 6D States are interrogated by both high energy pulses and low power CW sources. We observe four-wave mixing, six-wave mixing, potential two-photon lasing, other unknown nonlinear processes, and the persistence of some processes at low thresholds. This system is also uniquely qualified to support two-photon lasing under the proper conditions.

Temporal mapping of photochemical reactions and molecular excited states with carbon specificity

NASA Astrophysics Data System (ADS)

Wang, K.; Murahari, P.; Yokoyama, K.; Lord, J. S.; Pratt, F. L.; He, J.; Schulz, L.; Willis, M.; Anthony, J. E.; Morley, N. A.; Nuccio, L.; Misquitta, A.; Dunstan, D. J.; Shimomura, K.; Watanabe, I.; Zhang, S.; Heathcote, P.; Drew, A. J.

2017-04-01

Photochemical reactions are essential to a large number of important industrial and biological processes. A method for monitoring photochemical reaction kinetics and the dynamics of molecular excitations with spatial resolution within the active molecule would allow a rigorous exploration of the pathway and mechanism of photophysical and photochemical processes. Here we demonstrate that laser-excited muon pump-probe spin spectroscopy (photo-μSR) can temporally and spatially map these processes with a spatial resolution at the single-carbon level in a molecule with a pentacene backbone. The observed time-dependent light-induced changes of an avoided level crossing resonance demonstrate that the photochemical reactivity of a specific carbon atom is modified as a result of the presence of the excited state wavefunction. This demonstrates the sensitivity and potential of this technique in probing molecular excitations and photochemistry.

Cardiac glycoside ouabain induces activation of ATF-1 and StAR expression by interacting with the α4 isoform of the sodium pump in Sertoli cells.

PubMed

Dietze, Raimund; Konrad, Lutz; Shihan, Mazen; Kirch, Ulrike; Scheiner-Bobis, Georgios

2013-03-01

Sertoli cells express α1 and α4 isoforms of the catalytic subunit of Na(+),K(+)-ATPase (sodium pump). Our recent findings demonstrated that interactions of the α4 isoform with cardiotonic steroids (CTS) like ouabain induce signaling cascades that resemble the so-called non-classical testosterone pathway characterized by activation of the c-Src/c-Raf/Erk1/2/CREB signaling cascade. Here we investigate a possible physiological significance of the activated cascade. The results obtained in the current investigation show that the ouabain-induced signaling cascade also leads to the activation of the CREB-related activating transcription factor 1 (ATF-1) in the Sertoli cell line 93RS2 in a concentration- and time-dependent manner, as demonstrated by detection of ATF-1 phosphorylated on Ser63 in western blots. The ouabain-activated ATF-1 protein was found to localize to the cell nuclei. The sodium pump α4 isoform mediates this activation, as it is ablated when cells are incubated with siRNA to the α4 isoform. Ouabain also leads to increased expression of steroidogenic acute regulator (StAR) protein, which has been shown to be a downstream consequence of CREB/ATF-1 activation. Taking into consideration that CTS are most likely produced endogenously, the demonstrated induction of StAR expression by ouabain establishes a link between CTS, the α4 isoform of the sodium pump, and steroidogenesis crucial for male fertility and reproduction. Copyright © 2012 Elsevier B.V. All rights reserved.

Evidence that the Na+-K+ leak/pump ratio contributes to the difference in endurance between fast- and slow-twitch muscles.

PubMed

Clausen, T; Overgaard, K; Nielsen, O B

2004-02-01

Muscles containing predominantly fast-twitch (type II) fibres [ext. dig. longus (EDL)] show considerably lower contractile endurance than muscles containing mainly slow-twitch (type I) fibres (soleus). To assess whether differences in Na+-K+ fluxes and excitability might contribute to this phenomenon, we compared excitation-induced Na+-K+ leaks, Na+ channels, Na+-K+ pump capacity, force and compound action potentials (M-waves) in rat EDL and soleus muscles. Isolated muscles were mounted for isometric contractions in Krebs-Ringer bicarbonate buffer and exposed to direct or indirect continuous or intermittent electrical stimulation. The time-course of force decline and concomitant changes in Na+-K+ exchange and M-waves were recorded. During continuous stimulation at 60-120 Hz, EDL showed around fivefold faster rate of force decline than soleus. This was associated with a faster loss of excitability as estimated from the area and amplitude of the M-waves. The net uptake of Na+ and the release of K+ per action potential were respectively 6.5- and 6.6-fold larger in EDL than in soleus, which may in part be due to the larger content of Na+ channels in EDL. During intermittent stimulation with 1 s 60 Hz pulse trains, EDL showed eightfold faster rate of force decline than soleus. The considerably lower contractile endurance of fast-twitch compared with slow-twitch muscles reflects differences in the rate of excitation-induced loss of excitability. This is attributed to the much larger excitation-induced Na+ influx and K+ efflux, leading to a faster rise in [K+]o in fast-twitch muscles. This may only be partly compensated by the concomitant activation of the Na+-K+ pumps, in particular in fibres showing large passive Na+-K+ leaks or reduced content of Na+-K+ pumps. Thus, endurance depends on the leak/pump ratio for Na+ and K+.

Advanced performance of small diaphragm vacuum pumps through the use of mechatronics

NASA Astrophysics Data System (ADS)

Lachenmann, R.; Dirscherl, J.

Oil-free diaphragm vacuum pumps have proven to be the best way in vacuum generation for the chemical laboratory and they also find increasing use as backing pumps for modern wide-range turbo molecular pumps. The majority of vacuum pumps in practical use pump only a rather small percentage of their lifetime at full gas load. A pump backing a turbo molecular pump does not have to pump a significant gas load when the high-vacuum pump is running at ultimate vacuum pressure. Also, for a vacuum distillation the vacuum pump has to operate at full speed only at the beginning to lower the pressure inside the system to a vacuum level where evaporation starts. In a rather leak-tight system the distillation process continues by evaporating from the hot liquid and condensing at the cold condenser without the need of a mechanical vacuum pump. Rotational speed controlled diaphragm pumps are now available through progress in mechatronics and offer high pumping speed capability for fast pump-down cycles and precise pressure control for distillations. At low gas load the rotational speed can be reduced, improving maintenance intervals, power consumption, noise, vibration and - surprisingly - also ultimate pressure. The different behaviour in pumping speed and ultimate pressure of rotational speed controlled diaphragm pumps in comparison to constant-speed pumps is related to the mechanical properties of the valves and gas dynamics .

Investigation of laser induced parametric interactions in optical waveguides and fibers

NASA Technical Reports Server (NTRS)

Yu, C.

1978-01-01

Experimental and theoretical aspects of the laser pump depletion characteristics in an optical fiber due to stimulated Raman scattering, and stimulated Brillouin scattering were studied. A review is presented of research in fiber transmission accompanied by stimulated scattering. Results of experimental work with tunable dye lasers and argon lasers are presented. The spectral profiles of the laser pump and its transmitted light through the fiber are given.

Na(+)-K (+) pump location and translocation during muscle contraction in rat skeletal muscle.

PubMed

Kristensen, Michael; Rasmussen, Martin Krøyer; Juel, Carsten

2008-08-01

Muscle contraction may up-regulate the number of Na(+)-K(+) pumps in the plasma membrane by translocation of subunits. Since there is still controversy about where this translocation takes place from and if it takes place at all, the present study used different techniques to characterize the translocation. Electrical stimulation and biotin labeling of rat muscle revealed a 40% and 18% increase in the amounts of the Na(+)-K(+) pump alpha(2) subunit and caveolin-3 (Cav-3), respectively, in the sarcolemma. Exercise induced a 36% and 19% increase in the relative amounts of the alpha(2) subunit and Cav-3, respectively, in an outer-membrane-enriched fraction and a 41% and 17% increase, respectively, in sarcolemma giant vesicles. The Na(+)-K(+) pump activity measured with the 3-O-MFPase assay was increased by 37% in giant vesicles from exercised rats. Immunoprecipitation with Cav-3 antibody showed that 17%, 11% and 14% of the alpha(1) subunits were associated with Cav-3 in soleus, extensor digitorum longus, and mixed muscles, respectively. For the alpha(2), the corresponding values were 17%, 5% and 16%. In conclusion; muscle contraction induces translocation of the alpha subunits, which is suggested to be caused partly by structural changes in caveolae and partly by translocation from an intracellular pool.

Vacuum space charge effects in sub-picosecond soft X-ray photoemission on a molecular adsorbate layer

DOE PAGES

Dell'Angela, M.; Anniyev, T.; Beye, M.; ...

2015-03-01

Vacuum space charge-induced kinetic energy shifts of O 1s and Ru 3d core levels in femtosecond soft X-ray photoemission spectra (PES) have been studied at a free electron laser (FEL) for an oxygen layer on Ru(0001). We fully reproduced the measurements by simulating the in-vacuum expansion of the photoelectrons and demonstrate the space charge contribution of the high-order harmonics in the FEL beam. Employing the same analysis for 400 nm pump-X-ray probe PES, we can disentangle the delay dependent Ru 3d energy shifts into effects induced by space charge and by lattice heating from the femtosecond pump pulse.

Temporal-spatial measurement of electron relaxation time in femtosecond laser induced plasma using two-color pump-probe imaging technique

NASA Astrophysics Data System (ADS)

Pan, Changji; Jiang, Lan; Wang, Qingsong; Sun, Jingya; Wang, Guoyan; Lu, Yongfeng

2018-05-01

The femtosecond (fs) laser is a powerful tool to study ultrafast plasma dynamics, especially electron relaxation in strong ionization of dielectrics. Herein, temporal-spatial evolution of femtosecond laser induced plasma in fused silica was investigated using a two-color pump-probe technique (i.e., 400 nm and 800 nm, respectively). We demonstrated that when ionized electron density is lower than the critical density, free electron relaxation time is inversely proportional to electron density, which can be explained by the electron-ion scattering regime. In addition, electron density evolution within plasma was analyzed in an early stage (first 800 fs) of the laser-material interaction.

Vacuum space charge effects in sub-picosecond soft X-ray photoemission on a molecular adsorbate layer.

PubMed

Dell'Angela, M; Anniyev, T; Beye, M; Coffee, R; Föhlisch, A; Gladh, J; Kaya, S; Katayama, T; Krupin, O; Nilsson, A; Nordlund, D; Schlotter, W F; Sellberg, J A; Sorgenfrei, F; Turner, J J; Öström, H; Ogasawara, H; Wolf, M; Wurth, W

2015-03-01

Vacuum space charge induced kinetic energy shifts of O 1s and Ru 3d core levels in femtosecond soft X-ray photoemission spectra (PES) have been studied at a free electron laser (FEL) for an oxygen layer on Ru(0001). We fully reproduced the measurements by simulating the in-vacuum expansion of the photoelectrons and demonstrate the space charge contribution of the high-order harmonics in the FEL beam. Employing the same analysis for 400 nm pump-X-ray probe PES, we can disentangle the delay dependent Ru 3d energy shifts into effects induced by space charge and by lattice heating from the femtosecond pump pulse.

Controlling nanoscale acoustic strains in silicon using chirped femtosecond laser pulses

NASA Astrophysics Data System (ADS)

Tzianaki, E.; Bakarezos, M.; Tsibidis, G. D.; Petrakis, S.; Loukakos, P. A.; Kosmidis, C.; Tatarakis, M.; Papadogiannis, N. A.

2016-06-01

The influence of femtosecond laser pulse chirp on laser-generated longitudinal acoustic strains in Si (100) monocrystal substrates is studied. Degenerate femtosecond pump-probe transient reflectivity measurements are performed using a layered structure of thin Ti transducer film on an Si substrate. Experimental results show that acoustic strains, manifested as strong Brillouin oscillations, are more effectively induced when negatively chirped femtosecond laser pulses pump the transducer. These results are theoretically supported by a modified thermo-mechanical model based on the combination of a revised two-temperature model and elasticity theory that takes into account the instantaneous frequency of the chirped femtosecond laser pump pulses.

Fluid-structure coupling in the guide vanes cascade of a pump-turbine scale model

NASA Astrophysics Data System (ADS)

Roth, S.; Hasmatuchi, V.; Botero, F.; Farhat, M.; Avellan, F.

2010-08-01

The present study concerns fluid-structure coupling phenomena occurring in a guide vane cascade of a pump-turbine scale model placed in the EPFL PF3 test rig. An advanced instrument set is used to monitor both vibrating structures and the surrounding flow. The paper highlights the interaction between vibrating guide vanes and the flow behavior. The pressure fluctuations in the stay vanes region are found to be strongly influenced by the amplitude of the vibrating guide vanes. Moreover, the flow induces different hydrodynamic damping on the vibrating guide vanes depending on the operating point of the pump-turbine.

Pump-Induced, Dual-Frequency Switching in a Short-Cavity, Ytterbium-Doped Fiber Laser

DOE Office of Scientific and Technical Information (OSTI.GOV)

Guan, W.; Marciante, J.R.

2008-07-23

Using a short linear cavity composed of a section of highly ytterbium-doped fiber surrounded by two fiber Bragg gratings, dual frequency switching is achieved by tuning the pump power of the laser. The dual-frequency switching is generated by the thermal effects of the absorbed pump in the ytterbium-doped fiber. At each frequency, the laser shows single-longitudinal-mode behavior. In each single-mode regime, the optical signal-to-noise ratio of the laser is greater than 50 dB. The dual-frequency, switchable, fiber laser can be designed for various applications by the careful selection of the two gratings.

Liquid jet pumped by rising gas bubbles

NASA Technical Reports Server (NTRS)

Hussain, N. A.; Siegel, R.

1975-01-01

A two-phase mathematical model is proposed for calculating the induced turbulent vertical liquid flow. Bubbles provide a large buoyancy force and the associated drag on the liquid moves the liquid upward. The liquid pumped upward consists of the bubble wakes and the liquid brought into the jet region by turbulent entrainment. The expansion of the gas bubbles as they rise through the liquid is taken into account. The continuity and momentum equations are solved numerically for an axisymmetric air jet submerged in water. Water pumping rates are obtained as a function of air flow rate and depth of submergence. Comparisons are made with limited experimental information in the literature.

Modeling of SBS Phase Conjugation in Multimode Step Index Fibers

DTIC Science & Technology

2008-03-01

cavity or in an external amplifier. Since pumping is never a perfectly efficient process, some heat will be introduced, and for very high pump powers...modes it supports, and the incident pump power. While theoretical investigations of SBS PCMs have been conducted by a num- ber of authors, the model...predictions about the phase conjugate fidelity that could be expected from a given pump intensity input coupled into a specific fiber. A numerical

Photon-phonon parametric oscillation induced by quadratic coupling in an optomechanical resonator

NASA Astrophysics Data System (ADS)

Zhang, Lin; Ji, Fengzhou; Zhang, Xu; Zhang, Weiping

2017-07-01

A direct photon-phonon parametric effect of quadratic coupling on the mean-field dynamics of an optomechanical resonator in the large-scale-movement regime is found and investigated. Under a weak pumping power, the mechanical resonator damps to a steady state with a nonlinear static response sensitively modified by the quadratic coupling. When the driving power increases beyond the static energy balance, the steady states lose their stabilities via Hopf bifurcations, and the resonator produces stable self-sustained oscillation (limit-circle behavior) of discrete energies with step-like amplitudes due to the parametric effect of quadratic coupling, which can be understood roughly by the power balance between gain and loss on the resonator. A further increase in the pumping power can induce a chaotic dynamic of the resonator via a typical routine of period-doubling bifurcation, but which can be stabilized by the parametric effect through an inversion-bifurcation process back to the limit-circle states. The bifurcation-to-inverse-bifurcation transitions are numerically verified by the maximal Lyapunov exponents of the dynamics, which indicate an efficient way of suppressing the chaotic behavior of the optomechanical resonator by quadratic coupling. Furthermore, the parametric effect of quadratic coupling on the dynamic transitions of an optomechanical resonator can be conveniently detected or traced by the output power spectrum of the cavity field.

Studies of rotationally inelastic collisions of NaK and NaCs with Ar and He perturbers

NASA Astrophysics Data System (ADS)

Jones, J.; Faust, C.; Richter, K.; Wolfe, C. M.; Ashman, S.; Malenda, R. F.; Weiser, P.; Carlus, S.; Fragale, A.; Hickman, A. P.; Huennekens, J.

2013-05-01

We report studies of rotationally inelastic collisions of Ar and He atoms with the molecules NaK and NaCs prepared in various ro-vibrational levels of the A1Σ+ electronic state. We use laser induced fluorescence (LIF) and polarization labeling (PL) spectroscopy in a pump-probe, two step excitation process. The pump excites the molecule to a ro-vibrational level (v , J) in the A state. The probe laser is scanned over transitions to the 31 Π state in NaK or the 53 Π state in NaCs. In addition to strong direct lines, we observe weak satellite lines that arise from collision-induced transitions of the A state level (v , J) to (v , J + ΔJ) . The ratio of intensities of the satellite line to the direct line in LIF and PL yields information about population and orientation transfer. Preliminary results show a strong propensity for collisions with ΔJ =even for NaK; the propensity is larger for He than for Ar. Collisions of NaCs with He show a similar propensity, but collisions of NaCs with Ar do not. Theoretical calculations are also underway. For He-NaK, we have completed potential surface calculations using GAMESS and coupled channel scattering calculations of rotational energy transfer and transfer of orientation. Work supported by NSF and XSEDE.

Startup of Pumping Units in Process Water Supplies with Cooling Towers at Thermal and Nuclear Power Plants

DOE Office of Scientific and Technical Information (OSTI.GOV)

Berlin, V. V., E-mail: vberlin@rinet.ru; Murav’ev, O. A., E-mail: muraviov1954@mail.ru; Golubev, A. V., E-mail: electronik@inbox.ru

Aspects of the startup of pumping units in the cooling and process water supply systems for thermal and nuclear power plants with cooling towers, the startup stages, and the limits imposed on the extreme parameters during transients are discussed.

In-situ Condition Monitoring of Components in Small Modular Reactors Using Process and Electrical Signature Analysis. Final report, volume 1. Development of experimental flow control loop, data analysis and plant monitoring

DOE Office of Scientific and Technical Information (OSTI.GOV)

Upadhyaya, Belle; Hines, J. Wesley; Damiano, Brian

The research and development under this project was focused on the following three major objectives: Objective 1: Identification of critical in-vessel SMR components for remote monitoring and development of their low-order dynamic models, along with a simulation model of an integral pressurized water reactor (iPWR). Objective 2: Development of an experimental flow control loop with motor-driven valves and pumps, incorporating data acquisition and on-line monitoring interface. Objective 3: Development of stationary and transient signal processing methods for electrical signatures, machinery vibration, and for characterizing process variables for equipment monitoring. This objective includes the development of a data analysis toolbox. Themore » following is a summary of the technical accomplishments under this project: - A detailed literature review of various SMR types and electrical signature analysis of motor-driven systems was completed. A bibliography of literature is provided at the end of this report. Assistance was provided by ORNL in identifying some key references. - A review of literature on pump-motor modeling and digital signal processing methods was performed. - An existing flow control loop was upgraded with new instrumentation, data acquisition hardware and software. The upgrading of the experimental loop included the installation of a new submersible pump driven by a three-phase induction motor. All the sensors were calibrated before full-scale experimental runs were performed. - MATLAB-Simulink model of a three-phase induction motor and pump system was completed. The model was used to simulate normal operation and fault conditions in the motor-pump system, and to identify changes in the electrical signatures. - A simulation model of an integral PWR (iPWR) was updated and the MATLAB-Simulink model was validated for known transients. The pump-motor model was interfaced with the iPWR model for testing the impact of primary flow perturbations (upsets) on plant parameters and the pump electrical signatures. Additionally, the reactor simulation is being used to generate normal operation data and data with instrumentation faults and process anomalies. A frequency controller was interfaced with the motor power supply in order to vary the electrical supply frequency. The experimental flow control loop was used to generate operational data under varying motor performance characteristics. Coolant leakage events were simulated by varying the bypass loop flow rate. The accuracy of motor power calculation was improved by incorporating the power factor, computed from motor current and voltage in each phase of the induction motor.- A variety of experimental runs were made for steady-state and transient pump operating conditions. Process, vibration, and electrical signatures were measured using a submersible pump with variable supply frequency. High correlation was seen between motor current and pump discharge pressure signal; similar high correlation was exhibited between pump motor power and flow rate. Wide-band analysis indicated high coherence (in the frequency domain) between motor current and vibration signals. - Wide-band operational data from a PWR were acquired from AMS Corporation and used to develop time-series models, and to estimate signal spectrum and sensor time constant. All the data were from different pressure transmitters in the system, including primary and secondary loops. These signals were pre-processed using the wavelet transform for filtering both low-frequency and high-frequency bands. This technique of signal pre-processing provides minimum distortion of the data, and results in a more optimal estimation of time constants of plant sensors using time-series modeling techniques.« less

Development of a programmable piggyback syringe pump and four-times-a-day injection regimen for superovulation in non-lactating Holstein cows

PubMed Central

IRSHAD, Abdul Razaq; SASAKI, Taihei; KUBO, Tomoaki; ODASHIMA, Naoyuki; KATANO, Keiji; OSAWA, Takeshi; TAKAHASHI, Toru; IZAIKE, Yoshiaki

2015-01-01

The objectives of the present study were to develop a programmable piggyback syringe pump for bovine superovulation and to evaluate the effects of a four-times-a-day injection regimen using the pump. Non-lactating Holstein cows were treated with a total of 30 armour units of porcine FSH by injection four times a day with the pump (study, n = 9) or injection twice a day manually (control, n = 9) for four consecutive days from D10 of the estrous cycle. The pump-driven program successfully induced superovulation in all cows tested. The numbers of small (3– < 5 mm in diameter) and large (≥ 10 mm in diameter) follicles were greater in the study group on D11-13 and D14, respectively. There were fewer unovulated follicles detected on D21 (7 days after estrus) in the study group than in the control group (1.2 ± 0.4 and 3.2 ± 0.6, respectively). PMID:26052155

Development of a programmable piggyback syringe pump and four-times-a-day injection regimen for superovulation in non-lactating Holstein cows.

PubMed

Irshad, Abdul Razaq; Sasaki, Taihei; Kubo, Tomoaki; Odashima, Naoyuki; Katano, Keiji; Osawa, Takeshi; Takahashi, Toru; Izaike, Yoshiaki

2015-01-01

The objectives of the present study were to develop a programmable piggyback syringe pump for bovine superovulation and to evaluate the effects of a four-times-a-day injection regimen using the pump. Non-lactating Holstein cows were treated with a total of 30 armour units of porcine FSH by injection four times a day with the pump (study, n = 9) or injection twice a day manually (control, n = 9) for four consecutive days from D10 of the estrous cycle. The pump-driven program successfully induced superovulation in all cows tested. The numbers of small (3- < 5 mm in diameter) and large (≥ 10 mm in diameter) follicles were greater in the study group on D11-13 and D14, respectively. There were fewer unovulated follicles detected on D21 (7 days after estrus) in the study group than in the control group (1.2 ± 0.4 and 3.2 ± 0.6, respectively).

Terahertz dielectric response of photoexcited carriers in Si revealed via single-shot optical-pump and terahertz-probe spectroscopy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Minami, Yasuo; Horiuchi, Kohei; Masuda, Kaisei

We have demonstrated accurate observations of terahertz (THz) dielectric response due to photoexcited carriers in a Si plate via single-shot optical-pump and THz-probe spectroscopy. In contrast to conventional THz time-domain spectroscopy, this spectroscopic technique allows single-shot detection of the THz response of materials at a given delay time between the pump and THz pulses, thereby sufficiently extending the time interval between the pump pulses. As a result, we can accurately measure the dielectric properties of materials, while avoiding artifacts in the response caused by the accumulation of long-lived photoexcited carriers. Using our single-shot scheme, the transmittance of a Si platemore » was measured in the range of 0.5–2.5 THz with different pump fluences. Based on a Drude model analysis, the optically induced complex dielectric constant, plasma frequency, and damping rate in the THz region were quantitatively evaluated.« less

CIDME: Short distances measured with long chirp pulses.

PubMed

Doll, Andrin; Qi, Mian; Godt, Adelheid; Jeschke, Gunnar

2016-12-01

Frequency-swept pulses have recently been introduced as pump pulses into double electron-electron resonance (DEER) experiments. A limitation of this approach is that the pump pulses need to be short in comparison to dipolar evolution periods. The "chirp-induced dipolar modulation enhancement" (CIDME) pulse sequence introduced in this work circumvents this limitation by means of longitudinal storage during the application of one single or two consecutive pump pulses. The resulting six-pulse sequence is closely related to the five-pulse "relaxation-induced dipolar modulation enhancement" (RIDME) pulse sequence: While dipolar modulation in RIDME is due to stochastic spin flips during longitudinal storage, modulation in CIDME is due to the pump pulse during longitudinal storage. Experimentally, CIDME is examined for Gd-Gd and nitroxide-nitroxide distance determination using a high-power Q-band spectrometer. Since longitudinal storage results in a 50% signal loss, comparisons between DEER using short chirp pump pulses of 64ns duration and CIDME using longer pump pulses are in favor of DEER. While the lower sensitivity restrains the applicability of CIDME for routine distance determination on high-power spectrometers, this result is not to be generalized to spectrometers having lower power and to specialized "non-routine" applications or different types of spin labels. In particular, the advantage of prolonged CIDME pump pulses is demonstrated for experiments at large frequency offset between the pumped and observed spins. At a frequency separation of 1GHz, where broadening due to dipolar pseudo-secular contributions becomes largely suppressed, a Gd-Gd modulation depth larger than 10% is achieved. Moreover, a CIDME experiment at deliberately reduced power underlines the potential of the new technique for spectrometers with lower power, as often encountered at higher microwave frequencies. With longitudinal storage times T below 10μs, however, CIDME appears rather susceptible to artifacts. For nitroxide-nitroxide experiments, these currently inhibit a faithful data analysis. To facilitate further developments, the artifacts are characterized experimentally. In addition, effects that are specific to the high spin of S=7/2 Gd-centers are examined. Herein, population transfer within the observer spin's multiplet due to the pump pulse as well as excitation of dipolar harmonics are discussed. Copyright © 2016 Elsevier Inc. All rights reserved.

IR-stimulated visible fluorescence in pink and brown diamond.

PubMed

Byrne, K S; Chapman, J G; Luiten, A N

2014-03-19

Irradiation of natural pink and brown diamond by middle-ultraviolet light (photon energy ϵ ≥ 4.1 eV ) is seen to induce anomalous fluorescence phenomena at N3 defect centres (structure N3-V). When diamonds primed in this fashion are subsequently exposed to infrared light (even with a delay of many hours), a transient burst of blue N3 fluorescence is observed. The dependence of this IR-triggered fluorescence on pump wavelength and intensity suggest that this fluorescence phenomena is intrinsically related to pink diamond photochromism. An energy transfer process between N3 defects and other defect species can account for both the UV-induced fluorescence intensity changes, and the apparent optical upconversion of IR light. From this standpoint, we consider the implications of this N3 fluorescence behaviour for the current understanding of pink diamond photochromism kinetics.

Transient lattice contraction in the solid-to-plasma transition

PubMed Central

Ferguson, Ken R.; Bucher, Maximilian; Gorkhover, Tais; Boutet, Sébastien; Fukuzawa, Hironobu; Koglin, Jason E.; Kumagai, Yoshiaki; Lutman, Alberto; Marinelli, Agostino; Messerschmidt, Marc; Nagaya, Kiyonobu; Turner, Jim; Ueda, Kiyoshi; Williams, Garth J.; Bucksbaum, Philip H.; Bostedt, Christoph

2016-01-01

In condensed matter systems, strong optical excitations can induce phonon-driven processes that alter their mechanical properties. We report on a new phenomenon where a massive electronic excitation induces a collective change in the bond character that leads to transient lattice contraction. Single large van der Waals clusters were isochorically heated to a nanoplasma state with an intense 10-fs x-ray (pump) pulse. The structural evolution of the nanoplasma was probed with a second intense x-ray (probe) pulse, showing systematic contraction stemming from electron delocalization during the solid-to-plasma transition. These findings are relevant for any material in extreme conditions ranging from the time evolution of warm or hot dense matter to ultrafast imaging with intense x-ray pulses or, more generally, any situation that involves a condensed matter-to-plasma transition. PMID:27152323

Cryogenic hydrogen-induced air-liquefaction technologies

NASA Technical Reports Server (NTRS)

Escher, William J. D.

1990-01-01

Extensive use of a special advanced airbreathing propulsion archives data base, as well as direct contacts with individuals who were active in the field in previous years, a technical assessment of cryogenic hydrogen induced air liquefaction, as a prospective onboard aerospace vehicle process, was performed and documented in 1986. The resulting assessment report is summarized. Technical findings relating the status of air liquefaction technology are presented both as a singular technical area, and also as that of a cluster of collateral technical areas including: Compact lightweight cryogenic heat exchangers; Heat exchanger atmospheric constituents fouling alleviation; Para/ortho hydrogen shift conversion catalysts; Hydrogen turbine expanders, cryogenic air compressors and liquid air pumps; Hydrogen recycling using slush hydrogen as heat sinks; Liquid hydrogen/liquid air rocket type combustion devices; Air Collection and Enrichment System (ACES); and Technically related engine concepts.

Metabolic and transcriptomic response of the wine yeast Saccharomyces cerevisiae strain EC1118 after an oxygen impulse under carbon-sufficient, nitrogen-limited fermentative conditions.

PubMed

Orellana, Marcelo; Aceituno, Felipe F; Slater, Alex W; Almonacid, Leonardo I; Melo, Francisco; Agosin, Eduardo

2014-05-01

During alcoholic fermentation, Saccharomyces cerevisiae is exposed to continuously changing environmental conditions, such as decreasing sugar and increasing ethanol concentrations. Oxygen, a critical nutrient to avoid stuck and sluggish fermentations, is only discretely available throughout the process after pump-over operation. In this work, we studied the physiological response of the wine yeast S. cerevisiae strain EC1118 to a sudden increase in dissolved oxygen, simulating pump-over operation. With this aim, an impulse of dissolved oxygen was added to carbon-sufficient, nitrogen-limited anaerobic continuous cultures. Results showed that genes related to mitochondrial respiration, ergosterol biosynthesis, and oxidative stress, among other metabolic pathways, were induced after the oxygen impulse. On the other hand, mannoprotein coding genes were repressed. The changes in the expression of these genes are coordinated responses that share common elements at the level of transcriptional regulation. Beneficial and detrimental effects of these physiological processes on wine quality highlight the dual role of oxygen in 'making or breaking wines'. These findings will facilitate the development of oxygen addition strategies to optimize yeast performance in industrial fermentations. © 2014 Federation of European Microbiological Societies. Published by John Wiley & Sons Ltd. All rights reserved.

Energy pumping in electrical circuits under avalanche noise.

PubMed

Kanazawa, Kiyoshi; Sagawa, Takahiro; Hayakawa, Hisao

2014-07-01

We theoretically study energy pumping processes in an electrical circuit with avalanche diodes, where non-Gaussian athermal noise plays a crucial role. We show that a positive amount of energy (work) can be extracted by an external manipulation of the circuit in a cyclic way, even when the system is spatially symmetric. We discuss the properties of the energy pumping process for both quasistatic and finite-time cases, and analytically obtain formulas for the amounts of the work and the power. Our results demonstrate the significance of the non-Gaussianity in energetics of electrical circuits.

Regenerative adsorbent heat pump

NASA Technical Reports Server (NTRS)

Jones, Jack A. (Inventor)

1991-01-01

A regenerative adsorbent heat pump process and system is provided which can regenerate a high percentage of the sensible heat of the system and at least a portion of the heat of adsorption. A series of at least four compressors containing an adsorbent is provided. A large amount of heat is transferred from compressor to compressor so that heat is regenerated. The process and system are useful for air conditioning rooms, providing room heat in the winter or for hot water heating throughout the year, and, in general, for pumping heat from a lower temperature to a higher temperature.

Application of programmable logic controllers to space simulation

NASA Technical Reports Server (NTRS)

Sushon, Janet

1992-01-01

Incorporating a state-of-the-art process control and instrumentation system into a complex system for thermal vacuum testing is discussed. The challenge was to connect several independent control systems provided by various vendors to a supervisory computer. This combination will sequentially control and monitor the process, collect the data, and transmit it to color a graphic system for subsequent manipulation. The vacuum system upgrade included: replacement of seventeen diffusion pumps with eight cryogenic pumps and one turbomolecular pump, replacing a relay based control system, replacing vacuum instrumentation, and upgrading the data acquisition system.

ISS Ammonia Pump Failure, Recovery, and Lesson Learned A Hydrodynamic Bearing Perspective

NASA Technical Reports Server (NTRS)

Bruckner, Robert J.; Manco, Richard A., II

2014-01-01

The design, development, and operation of long duration spaceflight hardware has become an evolutionary process in which meticulous attention to details and lessons learned from previous experiences play a critical role. Invaluable to this process is the ability to retrieve and examine spaceflight hardware that has experienced a premature failure. While these situations are rare and unfortunate, the failure investigation and recovery from the event serve a valuable purpose in advancing future space mechanism development. Such a scenario began on July 31, 2010 with the premature failure of an ammonia pump on the external active thermal control system of the International Space Station. The ground-based inspections of the returned pump and ensuing failure investigation revealed five potential bearing forces that were un-accounted for in the design phase and qualification testing of the pump. These forces could combine in a number of random orientations to overload the pump bearings leading to solid-surface contact, wear, and premature failure. The recovery plan identified one of these five forces as being related to the square of the operating speed of the pump and this fact was used to recover design life through a change in flight rules for the operation of the pump module. Through the course of the failure investigation, recovery, and follow-on assessment of pump wear life, design guidance has been developed to improve the life of future mechanically pumped thermal control systems for both human and robotic exploration missions.

Application of LIF technique for the space- and time-resolved monitoring of pollutant gas decomposition in nonthermal plasma reactors

NASA Astrophysics Data System (ADS)

Mizeraczyk, Jerzy; Ohkubo, Toshikazu; Kanazawa, Seiji; Kocik, Marek

2003-10-01

Laser-induced fluorescence (LIF) technique aided by intensified CCD light signal detection and fast digital image processing is demonstrated to be a useful diagnostic method for in-situ observation of the discharge-induced plasma-chemistry processes responsible for NOx(NO + NO2) decomposition occurring in non-thermal plasma reactors. In this paper a method and results of the LIF measurement of two-dimensional distribution of the ground-state NO molecule density inside a DC positive streamer corona reactor during NO removal from a flue gas simulator [air/NO(up to 300 ppm)] are presented. Either a needle-to-plate or nozzle-to-plate electrode system, having an electrode gap of 30-50 mm was used for generating the corona discharge in the reactor. The LIF monitoring of NO molecules was carried out under the steady-state DC corona discharge condition. The laser-induced fluorescence on the transition NO X2Π(v"=0)<--A2Σ+(v'=0) at λ=226nm was chosen for monitoring ground-state NO molecules in the reactor. This transition was induced by irradiation of the NO molecules with UV laser pulses generated by a laser system consisted of a XeF excimer laser, dye laser and BBO crystal. The laser pulses from the XeF excimer laser (Lambda Physik, Complex 150, λ=351 nm) pumped the dye laser (Lambda Physik, Scanmate) with Coumarin 47 as a dye, which generated the laser beam of a wavelength turned around λ=450 nm. Then, the tuned dye laser beam pumped the BBO crystal in which the second harmonic radiation of a wavelength correspondingly tuned around λ=226 nm was generated. The 226-nm UV laser pulses of energy of 0.8-2 mJ and duration of about 20 ns were transformed into the form of the so-called laser sheet (width of 1 mm, height of 30-50 mm) which passed between the electrodes through the operating gas. The obtained results, presented in the form of images, which illustrated the two-dimensional distributions of NO molecule concentration in the non-thermal reactor, showed that the corona discharge-induced removal of NO molecules occurred not only in the vicinity of the plasma region formed by the corona discharge-induced removal of NO molecules occurred not only in the vicinity of the plasma region formed by the corona streamers and in the downstream region of the reactor but also in the upstream region of the reactor, i.e. before the flue gas simulator has entered the plasma region. This information obtained owing to the LIF technique, is important for the understanding of the plasma-chemistry processes responsible for NOx decomposition in non-thermal plasma reactors and for optimising their performance.

Normetex Pump Alternatives Study

DOE Office of Scientific and Technical Information (OSTI.GOV)

Clark, Elliot A.

2013-04-25

A mainstay pump for tritium systems, the Normetex scroll pump, is currently unavailable because the Normetex company went out of business. This pump was an all-metal scroll pump that served tritium processing facilities very well. Current tritium system operators are evaluating replacement pumps for the Normetex pump and for general used in tritium service. An all-metal equivalent alternative to the Normetex pump has not yet been identified. 1. The ideal replacement tritium pump would be hermetically sealed and contain no polymer components or oils. Polymers and oils degrade over time when they contact ionizing radiation. 2. Halogenated polymers (containing fluorine,more » chlorine, or both) and oils are commonly found in pumps. These materials have many properties that surpass those of hydrocarbon-based polymers and oils, including thermal stability (higher operating temperature) and better chemical resistance. Unfortunately, they are less resistant to degradation from ionizing radiation than hydrocarbon-based materials (in general). 3. Polymers and oils can form gaseous, condensable (HF, TF), liquid, and solid species when exposed to ionizing radiation. For example, halogenated polymers form HF and HCl, which are extremely corrosive upon reaction with water. If a pump containing polymers or oils must be used in a tritium system, the system must be designed to be able to process the unwanted by-products. Design features to mitigate degradation products include filters and chemical or physical traps (eg. cold traps, oil traps). 4. Polymer components can work in tritium systems, but must be replaced regularly. Polymer components performance should be monitored or be regularly tested, and regular replacement of components should be viewed as an expected normal event. A radioactive waste stream must be established to dispose of used polymer components and oil with an approved disposal plan developed based on the facility location and its regulators. Polymers have varying resistances to ionizing radiation - aromatic polymers such as polyimide Vespel (TM) and the elastomer EPDM (ethylene propylene diene monomer) have been found to be more resistant to degradation in tritium than other polymers. This report presents information to help select replacement pumps for Normetex pumps in tritium systems. Several pumps being considered as Normetex replacement pumps are discussed.« less

78 FR 58535 - Hydropower Regulatory Efficiency Act of 2013; Supplemental Notice of Workshop

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-24

... license for hydropower development at non-powered dams and closed-loop pumped storage projects in... for licensing hydropower development at non-powered dams and closed-loop pumped storage projects... closed- loop pumped storage) affect the steps included in a two-year process? 3.9 Should there be a...

The effect of bacon pump retention levels following thermal processing on bacon slice composition and sensory characteristics.

PubMed

Sivendiran, T; Wang, L M; Huang, S; Bohrer, B M

2018-06-01

The objective was to evaluate the effect of belly pump uptake and cook yield during processing on bacon slice composition and sensory attributes. A total of forty-four bellies were commercially sourced and randomly assigned to two experiments. Each experiment consisted of one smokehouse cooking cycle. Within each experiment, bellies were separated at the medial point and one belly half was assigned to a high pump uptake treatment (HIGH; target of 30% uptake) and the remaining belly half was assigned to a normal pump uptake treatment (NORM; target of 15% uptake). In experiment-1, cook yields were 107.79% for the HIGH bellies and 101.52% for the NORM bellies. In experiment-2, cook yields were 97.41% for the HIGH bellies and 94.74% for the NORM bellies. Overall, bacon slice composition and sensory attributes of bacon from bellies with greater pump retention were largely unaffected, accordingly it was concluded that cook yields ranging in level of pump retention does not affect most attributes of bacon. Copyright © 2018 Elsevier Ltd. All rights reserved.

Reversing the pump dependence of a laser at an exceptional point

PubMed Central

Brandstetter, M.; Liertzer, M.; Deutsch, C.; Klang, P.; Schöberl, J.; Türeci, H. E.; Strasser, G.; Unterrainer, K.; Rotter, S.

2014-01-01

When two resonant modes in a system with gain or loss coalesce in both their resonance position and their width, a so-called exceptional point occurs, which acts as a source of non-trivial physics in a diverse range of systems. Lasers provide a natural setting to study such non-Hermitian degeneracies, as they feature resonant modes and a gain material as their basic constituents. Here we show that exceptional points can be conveniently induced in a photonic molecule laser by a suitable variation of the applied pump. Using a pair of coupled microdisk quantum cascade lasers, we demonstrate that in the vicinity of these exceptional points the coupled laser shows a characteristic reversal of its pump dependence, including a strongly decreasing intensity of the emitted laser light for increasing pump power. PMID:24925314

Observational Inferences of Lateral Eddy Diffusivity in the Halocline of the Beaufort Gyre

NASA Astrophysics Data System (ADS)

Meneghello, Gianluca; Marshall, John; Cole, Sylvia T.; Timmermans, Mary-Louise

2017-12-01

Using Ekman pumping rates mediated by sea ice in the Arctic Ocean's Beaufort Gyre (BG), the magnitude of lateral eddy diffusivities required to balance downward pumping is inferred. In this limit—that of vanishing residual-mean circulation—eddy-induced upwelling exactly balances downward pumping. The implied eddy diffusivity varies spatially and decays with depth, with values of 50-400 m2/s. Eddy diffusivity estimated using mixing length theory applied to BG mooring data exhibits a similar decay with depth and range of values from 100 m2/s to more than 600 m2/s. We conclude that eddy diffusivities in the BG are likely large enough to balance downward Ekman pumping, arresting the deepening of the gyre and suggesting that eddies play a zero-order role in buoyancy and freshwater budgets of the BG.

Reducing Liquid Loss during Ullage Venting in Microgravity

NASA Technical Reports Server (NTRS)

Nguyen, Bich; Nguyen, Lauren

2008-01-01

A centripetal-force-based liquid/gas separator has been proposed as a means of reducing the loss of liquid during venting of the ullage of a tank in microgravity as a new supply of liquid is pumped into the tank. Centripetal-force-based liquid/gas separators are used on Earth, where mechanical drives (e.g., pumps and spinners) are used to impart flow speeds sufficient to generate centripetal forces large enough to effect separation of liquids from gases. For the proposed application, the separator would be designed so that there would be no need for such a pump because the tank-pressure-induced outflow speed during venting of the ullage would be sufficient for centripetal separation. A relatively small pump would be used, not for separation, but for returning the liquid recovered by the separator to the tank.

Femtosecond Nonlinearities in Indium Gallium Arsenic Phosphide Diode Lasers

NASA Astrophysics Data System (ADS)

Hall, Katherine Lavin

Semiconductor optical amplifiers are receiving increasing attention for possible applications to broadband optical communication and switching systems. In this thesis we report the results of an extensive experimental study of the ultrafast gain and refractive index nonlinearities in 1.5 μm InGaAsP laser diode amplifiers. The temporal resolution afforded by the femtosecond optical pulses used in these experiments allows us to study carrier interactions with other carriers as well as carrier interactions with the lattice. The 100-200 fs optical pulses used in the pump -probe experiments are generated by an Additive Pulse Modelocked color center laser. The measured group velocity dispersion in the diodes ranged from -0.6 to -0.95 mu m^{-1 }. Differences in the group velocity for TE - and TM-polarized pulses suggested that cross-polarized pump-probe pulses walk off from each other in the diode. This walk-off can diminish the time resolution of some experiments. A novel heterodyne pump-probe technique was developed to distinguish collinear, copolarized, pump and probe pulses that were nominally at the same wavelength. Comparing cross-polarized and copolarized pump-probe results yielded new information about the physical mechanisms responsible for nonlinear gain in the diodes. We observed a gain compression across the entire bandwidth of the diode, associated with carrier heating. The hot carrier distribution cooled back to the lattice temperature with a 0.6 to 1.0 ps time constant, depending on the device structure. In addition, we observed a 0.1 to 0.25 ps delay in onset of carrier heating. Large gain compression due to two photon absorption was also observed. A small portion of the nonlinear gain is attributed to spectral hole burning. Pulsewidth-dependent output saturation energies were explained by a rate equation model that included the effect of carrier heating. Measurements of pump-induced probe phase changes revealed index nonlinearities due to delayed carrier heating and an instantaneous electronic, or virtual process. (Copies available exclusively from MIT Libraries, Rm. 14-0551, Cambridge, MA 02139-4307. Ph. 617 -253-5668; Fax 617-253-1690.).

Electromagnetically Induced Absorption (EIA) and a ``Twist'' on Nonlinear Magneto-optical Rotation (NMOR) with Cold Atoms

NASA Astrophysics Data System (ADS)

Kunz, Paul; Meyer, David; Quraishi, Qudsia

2015-05-01

Within the class of nonlinear optical effects that exhibit sub-natural linewidth features, electromagnetically induced transparency (EIT) and nonlinear magneto-optical rotation (NMOR) stand out as having made dramatic impacts on various applications including atomic clocks, magnetometry, and single photon storage. A related effect, known as electromagnetically induced absorption (EIA), has received less attention in the literature. Here, we report on the first observation of EIA in cold atoms using the Hanle configuration, where a single laser beam is used to both pump and probe the atoms while sweeping a magnetic field through zero along the beam direction. We find that, associated with the EIA peak, a ``twist'' appears in the corresponding NMOR signal. A similar twist has been previously noted by Budker et al., in the context of warm vapor optical magnetometry, and was ascribed to optical pumping through nearby hyperfine levels. By studying this feature through numerical simulations and cold atom experiments, thus rendering the hyperfine levels well resolved, we enhance the understanding of the optical pumping mechanism behind it, and elucidate its relation to EIA. Finally, we demonstrate a useful application of these studies through a simple and rapid method for nulling background magnetic fields within our atom chip apparatus.

Waste Heat Recovery and Recycling in Thermal Separation Processes: Distillation, Multi-Effect Evaporation (MEE) and Crystallization Processes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Emmanuel A. Dada; Chandrakant B. Panchal; Luke K. Achenie

Evaporation and crystallization are key thermal separation processes for concentrating and purifying inorganic and organic products with energy consumption over 1,000 trillion Btu/yr. This project focused on a challenging task of recovering low-temperature latent heat that can have a paradigm shift in the way thermal process units will be designed and operated to achieve high-energy efficiency and significantly reduce the carbon footprint as well as water footprint. Moreover, this project has evaluated the technical merits of waste-heat powered thermal heat pumps for recovery of latent heat from distillation, multi-effect evaporation (MEE), and crystallization processes and recycling into the process. Themore » Project Team has estimated the potential energy, economics and environmental benefits with the focus on reduction in CO2 emissions that can be realized by 2020, assuming successful development and commercialization of the technology being developed. Specifically, with aggressive industry-wide applications of heat recovery and recycling with absorption heat pumps, energy savings of about 26.7 trillion Btu/yr have been estimated for distillation process. The direct environmental benefits of this project are the reduced emissions of combustible products. The estimated major reduction in environmental pollutants in the distillation processes is in CO2 emission equivalent to 3.5 billion lbs/year. Energy consumption associated with water supply and treatments can vary between 1,900 kWh and 23,700 kWh per million-gallon water depending on sources of natural waters [US DOE, 2006]. Successful implementation of this technology would significantly reduce the demand for cooling-tower waters, and thereby the use and discharge of water treatment chemicals. The Project Team has also identified and characterized working fluid pairs for the moderate-temperature heat pump. For an MEE process, the two promising fluids are LiNO3+KNO3+NANO3 (53:28:19 ) and LiNO3+KNO3+NANO2(53:35:12). And for an H2O2 distillation process, the two promising fluids are Trifluoroethanol (TFE) + Triethylene Glycol Dimethyl ether (DMETEG) and Ammonia+ Water. Thermo-physical properties calculated by Aspen+ are reasonably accurate. Documentation of the installation of pilot-plants or full commercial units were not found in the literature for validating thermo-physical properties in an operating unit. Therefore, it is essential to install a pilot-scale unit to verify thermo-physical properties of working fluid pairs and validate the overall efficiency of the thermal heat pump at temperatures typical of distillation processes. For an HO2 process, the ammonia-water heat pump system is more compact and preferable than the TFE-DMETEG heat pump. The ammonia-water heat pump is therefore recommended for the H2O2 process. Based on the complex nature of the heat recovery system, we anticipated that capital costs could make investments financially unattractive where steam costs are low, especially where co-generation is involved. We believe that the enhanced heat transfer equipment has the potential to significantly improve the performance of TEE crystallizers, independent of the absorption heat-pump recovery system. Where steam costs are high, more detailed design/cost engineering will be required to verify the economic viability of the technology. Due to the long payback period estimated for the TEE open system, further studies on the TEE system are not warranted unless there are significant future improvements to heat pump technology. For the H2O2 distillation cycle heat pump waste heat recovery system, there were no significant process constraints and the estimated 5 years payback period is encouraging. We therefore recommend further developments of application of the thermal heat pump in the H2O2 distillation process with the focus on the technical and economic viability of heat exchangers equipped with the state-of-the-art enhancements. This will require additional funding for a prototype unit to validate enhanced thermal performances of heat transfer equipment, evaluate the fouling characteristics in field testing, and remove the uncertainty factors included in the estimated payback period for the H2O2 distillation system.« less

Induction of endoplasmic reticulum calcium pump expression during early leukemic B cell differentiation.

PubMed

Aït Ghezali, Lamia; Arbabian, Atousa; Roudot, Hervé; Brouland, Jean-Philippe; Baran-Marszak, Fanny; Salvaris, Evelyn; Boyd, Andrew; Drexler, Hans G; Enyedi, Agnes; Letestu, Remi; Varin-Blank, Nadine; Papp, Bela

2017-06-26

Endoplasmic reticulum (ER) calcium storage and release play important roles in B lymphocyte maturation, survival, antigen-dependent cell activation and immunoglobulin synthesis. Calcium is accumulated in the endoplasmic reticulum (ER) by Sarco/Endoplasmic Reticulum Calcium ATPases (SERCA enzymes). Because lymphocyte function is critically dependent on SERCA activity, it is important to understand qualitative and quantitative changes of SERCA protein expression that occur during B lymphoid differentiation and leukemogenesis. In this work we investigated the modulation of SERCA expression during the pharmacologically induced differentiation of leukemic precursor B lymphoblast cell lines that carry the E2A-PBX1 fusion oncoprotein. Changes of SERCA levels during differentiation were determined and compared to those of established early B lymphoid differentiation markers. SERCA expression of the cells was compared to that of mature B cell lines as well, and the effect of the direct inhibition of SERCA-dependent calcium transport on the differentiation process was investigated. We show that E2A-PBX1 + leukemia cells simultaneously express SERCA2 and SERCA3-type calcium pumps; however, their SERCA3 expression is markedly inferior to that of mature B cells. Activation of protein kinase C enzymes by phorbol ester leads to phenotypic differentiation of the cells, and this is accompanied by the induction of SERCA3 expression. Direct pharmacological inhibition of SERCA-dependent calcium transport during phorbol ester treatment interferes with the differentiation process. These data show that the calcium pump composition of the ER is concurrent with increased SERCA3 expression during the differentiation of precursor B acute lymphoblastic leukemia cells, that a cross-talk exists between SERCA function and the control of differentiation, and that SERCA3 may constitute an interesting new marker for the study of early B cell phenotype.

Observation of femtosecond X-ray interactions with matter using an X-ray–X-ray pump–probe scheme

PubMed Central

Inoue, Ichiro; Inubushi, Yuichi; Sato, Takahiro; Tono, Kensuke; Katayama, Tetsuo; Kameshima, Takashi; Ogawa, Kanade; Togashi, Tadashi; Owada, Shigeki; Amemiya, Yoshiyuki; Tanaka, Takashi; Hara, Toru

2016-01-01

Resolution in the X-ray structure determination of noncrystalline samples has been limited to several tens of nanometers, because deep X-ray irradiation required for enhanced resolution causes radiation damage to samples. However, theoretical studies predict that the femtosecond (fs) durations of X-ray free-electron laser (XFEL) pulses make it possible to record scattering signals before the initiation of X-ray damage processes; thus, an ultraintense X-ray beam can be used beyond the conventional limit of radiation dose. Here, we verify this scenario by directly observing femtosecond X-ray damage processes in diamond irradiated with extraordinarily intense (∼1019 W/cm2) XFEL pulses. An X-ray pump–probe diffraction scheme was developed in this study; tightly focused double–5-fs XFEL pulses with time separations ranging from sub-fs to 80 fs were used to excite (i.e., pump) the diamond and characterize (i.e., probe) the temporal changes of the crystalline structures through Bragg reflection. It was found that the pump and probe diffraction intensities remain almost constant for shorter time separations of the double pulse, whereas the probe diffraction intensities decreased after 20 fs following pump pulse irradiation due to the X-ray–induced atomic displacement. This result indicates that sub-10-fs XFEL pulses enable conductions of damageless structural determinations and supports the validity of the theoretical predictions of ultraintense X-ray–matter interactions. The X-ray pump–probe scheme demonstrated here would be effective for understanding ultraintense X-ray–matter interactions, which will greatly stimulate advanced XFEL applications, such as atomic structure determination of a single molecule and generation of exotic matters with high energy densities. PMID:26811449

Understanding and eliminating artifact signals from diffusely scattered pump beam in measurements of rough samples by time-domain thermoreflectance (TDTR).

PubMed

Sun, Bo; Koh, Yee Kan

2016-06-01

Time-domain thermoreflectance (TDTR) is a pump-probe technique frequently applied to measure the thermal transport properties of bulk materials, nanostructures, and interfaces. One of the limitations of TDTR is that it can only be employed to samples with a fairly smooth surface. For rough samples, artifact signals are collected when the pump beam in TDTR measurements is diffusely scattered by the rough surface into the photodetector, rendering the TDTR measurements invalid. In this paper, we systemically studied the factors affecting the artifact signals due to the pump beam leaked into the photodetector and thus established the origin of the artifact signals. We find that signals from the leaked pump beam are modulated by the probe beam due to the phase rotation induced in the photodetector by the illumination of the probe beam. As a result of the modulation, artifact signals due to the leaked pump beam are registered in TDTR measurements as the out-of-phase signals. We then developed a simple approach to eliminate the artifact signals due to the leaked pump beam. We verify our leak-pump correction approach by measuring the thermal conductivity of a rough InN sample, when the signals from the leaked pump beam are significant. We also discuss the advantages of our new method over the two-tint approach and its limitations. Our new approach enables measurements of the thermal conductivity of rough samples using TDTR.

Understanding and eliminating artifact signals from diffusely scattered pump beam in measurements of rough samples by time-domain thermoreflectance (TDTR)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sun, Bo; Koh, Yee Kan, E-mail: mpekyk@nus.edu.sg; Centre of Advanced 2D Materials, National University of Singapore, Singapore 117542

Time-domain thermoreflectance (TDTR) is a pump-probe technique frequently applied to measure the thermal transport properties of bulk materials, nanostructures, and interfaces. One of the limitations of TDTR is that it can only be employed to samples with a fairly smooth surface. For rough samples, artifact signals are collected when the pump beam in TDTR measurements is diffusely scattered by the rough surface into the photodetector, rendering the TDTR measurements invalid. In this paper, we systemically studied the factors affecting the artifact signals due to the pump beam leaked into the photodetector and thus established the origin of the artifact signals.more » We find that signals from the leaked pump beam are modulated by the probe beam due to the phase rotation induced in the photodetector by the illumination of the probe beam. As a result of the modulation, artifact signals due to the leaked pump beam are registered in TDTR measurements as the out-of-phase signals. We then developed a simple approach to eliminate the artifact signals due to the leaked pump beam. We verify our leak-pump correction approach by measuring the thermal conductivity of a rough InN sample, when the signals from the leaked pump beam are significant. We also discuss the advantages of our new method over the two-tint approach and its limitations. Our new approach enables measurements of the thermal conductivity of rough samples using TDTR.« less

γ irradiation induced effects on bismuth active centres and related photoluminescence properties of Bi/Er co-doped optical fibres

PubMed Central

Sporea, D.; Mihai, L.; Neguţ, D.; Luo, Yanhua; Yan, Binbin; Ding, Mingjie; Wei, Shuen; Peng, Gang-Ding

2016-01-01

We investigate the effects of γ irradiation on bismuth active centres (BACs) and related photoluminescence properties of bismuth/erbium co-doped silica fibre (BEDF), [Si] ~28, [Ge] ~1.60, [Al] ~0.10, [Er] ~ <0.10 and [Bi] ~0.10 atom%, fabricated by in-situ solution doping and Modified Chemical Vapor Deposition (MCVD). The samples were irradiated at 1 kGy, 5 kGy, 15 kGy, 30 kGy and 50 kGy doses, and dose rate of 5.5 kGy/h, at room temperature. The optical properties of BEDF samples are tested before and after γ irradiation. We found that high dose γ irradiation could significantly influence the formation and composition of BACs and their photoluminescence performance, as important changes in absorption and emission properties associated with the 830 nm pump produces the direct evidence of γ irradiation effects on BAC-Si. We notice that the saturable to unsaturable absorption ratio at pump wavelength could be increased with high dose γ irradiation, indicating that emission and pump efficiency could be increased by γ irradiation. Our experimental results also reveal good radiation survivability of the BEDF under low and moderate γ irradiation. Our investigation suggests the existence of irradiation related processing available for tailoring the photoluminescence properties and performance of bismuth doped/co-doped fibres. PMID:27440386

Computational Fluid Dynamics (CFD) applications in rocket propulsion analysis and design

NASA Technical Reports Server (NTRS)

Mcconnaughey, P. K.; Garcia, R.; Griffin, L. W.; Ruf, J. H.

1993-01-01

Computational Fluid Dynamics (CFD) has been used in recent applications to affect subcomponent designs in liquid propulsion rocket engines. This paper elucidates three such applications for turbine stage, pump stage, and combustor chamber geometries. Details of these applications include the development of a high turning airfoil for a gas generator (GG) powered, liquid oxygen (LOX) turbopump, single-stage turbine using CFD as an integral part of the design process. CFD application to pump stage design has emphasized analysis of inducers, impellers, and diffuser/volute sections. Improvements in pump stage impeller discharge flow uniformity have been seen through CFD optimization on coarse grid models. In the area of combustor design, recent CFD analysis of a film cooled ablating combustion chamber has been used to quantify the interaction between film cooling rate, chamber wall contraction angle, and geometry and their effects of these quantities on local wall temperature. The results are currently guiding combustion chamber design and coolant flow rate for an upcoming subcomponent test. Critical aspects of successful integration of CFD into the design cycle includes a close-coupling of CFD and design organizations, quick turnaround of parametric analyses once a baseline CFD benchmark has been established, and the use of CFD methodology and approaches that address pertinent design issues. In this latter area, some problem details can be simplified while retaining key physical aspects to maintain analytical integrity.

Femtosecond optical parametric amplification in BBO and KTA driven by a Ti:sapphire laser for LIDT testing and diagnostic development

NASA Astrophysics Data System (ADS)

Meadows, Alexander R.; Cupal, Josef; Hříbek, Petr; Durák, Michal; Kramer, Daniel; Rus, Bedřich

2017-05-01

We present the design of a collinear femtosecond optical parametric amplification (OPA) system producing a tunable output at wavelengths between 1030 nm and 1080 nm from a Ti:Sapphire pump laser at a wavelength of 795 nm. Generation of a supercontinuum seed pulse is followed by one stage of amplification in Beta Barium Borate (BBO) and two stages of amplification in Potassium Titanyle Arsenate (KTA), resulting in a 225 μJ output pulse with a duration of 90 fs. The output of the system has been measured by self-referenced spectral interferometry to yield the complete spectrum and spectral phase of the pulse. When compared to KTP, the greater transparency of KTA in the spectral range from 3 - 4 μm allows for reduced idler absorption and enhanced gain from the OPA process when it is pumped by the fundamental frequency of a Ti:sapphire laser. In turn, the use of the Ti:sapphire fundamental at 795 nm as a pump improves the efficiency with which light can be converted to wavelengths between 1030 nm and 1080 nm and subsequently used to test components for Nd-based laser systems. This OPA system is operated at 1 kHz for diagnostic development and laser-induced damage threshold testing of optical components for the ELI-Beamlines project.

Ultrafast time-resolved pump-probe spectroscopy of PYP by a sub-8 fs pulse laser at 400 nm.

PubMed

Liu, Jun; Yabushita, Atsushi; Taniguchi, Seiji; Chosrowjan, Haik; Imamoto, Yasushi; Sueda, Keiichi; Miyanaga, Noriaki; Kobayashi, Takayoshi

2013-05-02

Impulsive excitation of molecular vibration is known to induce wave packets in both the ground state and excited state. Here, the ultrafast dynamics of PYP was studied by pump-probe spectroscopy using a sub-8 fs pulse laser at 400 nm. The broadband spectrum of the UV pulse allowed us to detect the pump-probe signal covering 360-440 nm. The dependence of the vibrational phase of the vibrational mode around 1155 cm(-1) on the probe photon energy was observed for the first time to our knowledge. The vibrational mode coupled to the electronic transition observed in the probe spectral ranges of 2.95-3.05 and 3.15-3.35 eV was attributed to the wave packets in the ground state and the excited state, respectively. The frequencies in the ground state and excited state were determined to be 1155 ± 1 and 1149 ± 1 cm(-1), respectively. The frequency difference is due to change after photoexcitation. This means a reduction of the bond strength associated with π-π* excitation, which is related to the molecular structure change associated with the primary isomerization process in the photocycle in PYP. Real-time vibrational modes at low frequency around 138, 179, 203, 260, and 317 cm(-1) were also observed and compared with the Raman spectrum for the assignment of the vibrational wave packet.

A Guide for Developing Standard Operating Job Procedures for the Pump Station Process Wastewater Treatment Facility. SOJP No. 3.

ERIC Educational Resources Information Center

Perley, Gordon F.

This is a guide for standard operating job procedures for the pump station process of wastewater treatment plants. Step-by-step instructions are given for pre-start up inspection, start-up procedures, continuous routine operation procedures, and shut-down procedures. A general description of the equipment used in the process is given. Two…

Possible involvement of membrane lipids peroxidation and oxidation of catalytically essential thiols of the cerebral transmembrane sodium pump as component mechanisms of iron-mediated oxidative stress-linked dysfunction of the pump's activity

PubMed Central

Omotayo, T.I.; Akinyemi, G.S.; Omololu, P.A.; Ajayi, B.O.; Akindahunsi, A.A.; Rocha, J.B.T.; Kade, I.J.

2014-01-01

The precise molecular events defining the complex role of oxidative stress in the inactivation of the cerebral sodium pump in radical-induced neurodegenerative diseases is yet to be fully clarified and thus still open. Herein we investigated the modulation of the activity of the cerebral transmembrane electrogenic enzyme in Fe2+-mediated in vitro oxidative stress model. The results show that Fe2+ inhibited the transmembrane enzyme in a concentration dependent manner and this effect was accompanied by a biphasic generation of aldehydic product of lipid peroxidation. While dithiothreitol prevented both Fe2+ inhibitory effect on the pump and lipid peroxidation, vitamin E prevented only lipid peroxidation but not inhibition of the pump. Besides, malondialdehyde (MDA) inhibited the pump by a mechanism not related to oxidation of its critical thiols. Apparently, the low activity of the pump in degenerative diseases mediated by Fe2+ may involve complex multi-component mechanisms which may partly involve an initial oxidation of the critical thiols of the enzyme directly mediated by Fe2+ and during severe progression of such diseases; aldehydic products of lipid peroxidation such as MDA may further exacerbate this inhibitory effect by a mechanism that is likely not related to the oxidation of the catalytically essential thiols of the ouabain-sensitive cerebral electrogenic pump. PMID:25618580

Microfluidic device and methods for focusing fluid streams using electroosmotically induced pressures

DOEpatents

Jacobson, Stephen C.; Ramsey, J. Michael

2010-06-01

A microfabricated device employing a bridging membrane and methods for electrokinetic transport of a liquid phase biological or chemical material using the same are described. The bridging membrane is deployed in or adjacent to a microchannel and permits either electric current flow or the transport of gas species, while inhibiting the bulk flow of material. The use of bridging membranes in accordance with this invention is applicable to electrokinetically inducing fluid flow to confine a selected material in a region of a microchannel that is not influenced by an electric field. Other structures for inducing fluid flow in accordance with this invention include nanochannel bridging membranes and alternating current fluid pumping devices. Applications of the bridging membranes according to this invention include the separation of species from a sample material, valving of fluids in a microchannel network, mixing of different materials in a microchannel, and the pumping of fluids.

Self-induced polar order of active Brownian particles in a harmonic trap.

PubMed

Hennes, Marc; Wolff, Katrin; Stark, Holger

2014-06-13

Hydrodynamically interacting active particles in an external harmonic potential form a self-assembled fluid pump at large enough Péclet numbers. Here, we give a quantitative criterion for the formation of the pump and show that particle orientations align in the self-induced flow field in surprising analogy to ferromagnetic order where the active Péclet number plays the role of inverse temperature. The particle orientations follow a Boltzmann distribution Φ(p) ∼ exp(Ap(z)) where the ordering mean field A scales with the active Péclet number and polar order parameter. The mean flow field in which the particles' swimming directions align corresponds to a regularized Stokeslet with strength proportional to swimming speed. Analytic mean-field results are compared with results from Brownian dynamics simulations with hydrodynamic interactions included and are found to capture the self-induced alignment very well.

An analysis of pump cavitation damage. [Space Shuttle main engine high pressure oxidizer turbopump

NASA Technical Reports Server (NTRS)

Brophy, M. C.; Stinebring, D. R.; Billet, M. L.

1985-01-01

The cavitation assessment for the space shuttle main engine high pressure oxidizer turbopump is documented. A model of the flow through the pump was developed. Initially, a computational procedure was used to analyze the flow through the inlet casing including the prediction of wakes downstream of the casing vanes. From these flow calculations, cavitation patterns on the inducer blades were approximated and the damage rate estimated. The model correlates the heavy damage on the housing and over the inducer with unsteady blade surface cavitation. The unsteady blade surface cavitation is due to the large incidence changes caused by the wakes of the upstream vanes. Very high cavitation damage rates are associated with this type of cavitation. Design recommendations for reducing the unsteady cavitation include removing the set of vanes closest to the inducer and modifying the remaining vanes.

A study of pump cavitation damage. [space shuttle main engine high pressure oxidizer turbopump

NASA Technical Reports Server (NTRS)

Brophy, M. C.; Stinebring, D. R.; Billet, M. L.

1983-01-01

The cavitation assessment for the space shuttle main engine high pressure oxidizer turbopump is documented. A model of the flow through the pump was developed. Initially, a computational procedure was used to analyze the flow through the inlet casing including the prediction of wakes downstream of the casing vanes. From these flow calculations, cavitation patterns on the inducer blades were approximated and the damage rate estimated. The model correlates the heavy damage on the housing and over the inducer with unsteady blade surface cavitation. The unsteady blade surface cavitation is due to the large incidence changes caused by the wakes of the upstream vanes. Very high cavitation damage rates are associated with this type of cavitation. Design recommendations for reducing the unsteady cavitation include removing the set of vanes closest to the inducer and modifying the remaining vanes.

Quasi-phase-matching of only even-order high harmonics.

PubMed

Diskin, Tzvi; Cohen, Oren

2014-03-24

High harmonic spectrum of a quasi-monochromatic pump that interacts with isotropic media consists of only odd-order harmonics. Addition of a secondary pump, e.g. a static field or the second harmonic of the primary pump, can results with generation of both odd and even harmonics of the primary pump. We propose a method for quasi-phase matching of only the even-order harmonics of the primary pump. We formulate a theory for this process and demonstrate it numerically. We also show that it leads to attosecond pulse trains with constant carrier envelop phase and high repetition rate.

Efforts to Improve Efficiency of Extraction Well Operation at the Fernald Preserve, Harrison, Ohio – 16177

DOE Office of Scientific and Technical Information (OSTI.GOV)

Glassmeyer, Cathy; Hooten, Gwen; Hertel, Bill

The Fernald Preserve, a former uranium processing facility that produced high-purity uranium metal products during the Cold War, is located in southwest Ohio. The facility became a US Department of Energy Office of Legacy Management (LM) site in November 2006, following completion of the Comprehensive Environmental Response, Compensation, and Liability Act environmental remediation and site restoration (with the exception of groundwater). When the site was turned over to LM, approximately 76.5 ha of the Great Miami Aquifer remained contaminated with uranium above the final remediation level of 30 μg/L. Here, uranium contamination is being removed from groundwater in the Greatmore » Miami Aquifer through a pump-and-treat operation, which is predicted to continue until 2033. Twenty extraction wells pump about 30 million liters per day. Operation of the system is impacted by iron in the groundwater that promotes iron fouling of the well pumps, motors, and screens. The design of the well field evolved over 21 years and reflected a conservative system that could respond to a wide range of pumping conditions. For instance, some of the extraction wells were sized with pumps and motors that would allow the well to pump up to 1890 L/min (500 gpm) if warranted. The added flexibility, though, came at the cost of operational efficiency. We describe the efforts that have been taken by LM since the Fernald site was transferred to LM to mitigate the operational impacts from the iron fouling aquifer conditions and improve the efficiency of the well-field operation. Variable-frequency drives were installed at six wells to replace flow control valves. Several wells with oversized pumps and motors were changed from 24-hour per day operation to 8-hour per day operation to allow the pumps to operate closer to their design flow rates. Pumps and motors were “right-sized” at many wells to improve pumping efficiency. The process used to rehabilitate (or clean) well screens was improved, and a process was developed to clean pumps without having to pull them from the well. To reduce pressure drops, improvements were also made to the configuration of the discharge piping. A new control system was installed for each well to allow local control and local tracking of energy used. The amount of energy used daily compared to number of gallons pumped provides a method to assess pump performance and determine when action is necessary to restore well pump efficiency. Additionally, the metrics being employed to help quantify well-field efficiency improvements are described, and the benefits achieved by proactively managing the pump-and-treat operation are presented.« less

Numerical simulation and optimization of casting process for complex pump

NASA Astrophysics Data System (ADS)

Liu, Xueqin; Dong, Anping; Wang, Donghong; Lu, Yanling; Zhu, Guoliang

2017-09-01

The complex shape of the casting pump body has large complicated structure and uniform wall thickness, which easy give rise to casting defects. The numerical simulation software ProCAST is used to simulate the initial top gating process, after analysis of the material and structure characteristics of the high-pressure pump. The filling process was overall smooth, not there the water shortage phenomenon. But the circular shrinkage defects appear at the bottom of casting during solidification process. Then, the casting parameters were optimized and adding cold iron in the bottom. The shrinkage weight was reduced from 0.00167g to 0.0005g. The porosity volume was reduced from 1.39cm3 to 0.41cm3. The optimization scheme is simulated and actual experimented. The defect has been significantly improved.

Stepwise pumping approach to improve free phase light hydrocarbon recovery from unconfined aquifers

NASA Astrophysics Data System (ADS)

Cooper, Grant S.; Peralta, Richard C.; Kaluarachchi, Jagath J.

1995-04-01

A stepwise, time-varying pumping approach is developed to improve free phase oil recovery of light non-aqueous phase liquids (LNAPL) from a homogeneous, unconfined aquifer. Stepwise pumping is used to contain the floating oil plume and obtain efficient free oil recovery. The graphical plots. The approach uses ARMOS ©, an areal two-dimensional multiphase flow, finite-element simulation model. Systematic simulations of free oil area changes to pumping rates are analyzed. Pumping rates are determined that achieve LNAPL plume containment at different times (i.e. 90, 180 and 360 days) for a planning period of 360 days. These pumping rates are used in reverse order as a stepwise (monotonically increasing) pumping strategy. This stepwise pumping strategy is analyzed further by performing additional simulations at different pumping rates for the last pumping period. The final stepwise pumping strategy is varied by factors of -25% and +30% to evaluate sensitivity in the free oil recovery process. Stepwise pumping is compared to steady pumping rates to determine the best free oil recovery strategy. Stepwise pumping is shown to improve oil recovery by increasing recoveredoil volume (11%) and decreasing residual oil (15%) when compared with traditional steady pumping strategies. The best stepwise pumping strategy recovers more free oil by reducing the amount of residual oil left in the system due to pumping drawdown. This stepwise pumping pproach can be used to enhance free oil recovery and provide for cost-effective design and management of LNAPL cleanup.

Sodium Pumps Mediate Activity-Dependent Changes in Mammalian Motor Networks

PubMed Central

Picton, Laurence D.; Nascimento, Filipe; Broadhead, Matthew J.; Sillar, Keith T.

2017-01-01

Ubiquitously expressed sodium pumps are best known for maintaining the ionic gradients and resting membrane potential required for generating action potentials. However, activity- and state-dependent changes in pump activity can also influence neuronal firing and regulate rhythmic network output. Here we demonstrate that changes in sodium pump activity regulate locomotor networks in the spinal cord of neonatal mice. The sodium pump inhibitor, ouabain, increased the frequency and decreased the amplitude of drug-induced locomotor bursting, effects that were dependent on the presence of the neuromodulator dopamine. Conversely, activating the pump with the sodium ionophore monensin decreased burst frequency. When more “natural” locomotor output was evoked using dorsal-root stimulation, ouabain increased burst frequency and extended locomotor episode duration, whereas monensin slowed and shortened episodes. Decreasing the time between dorsal-root stimulation, and therefore interepisode interval, also shortened and slowed activity, suggesting that pump activity encodes information about past network output and contributes to feedforward control of subsequent locomotor bouts. Using whole-cell patch-clamp recordings from spinal motoneurons and interneurons, we describe a long-duration (∼60 s), activity-dependent, TTX- and ouabain-sensitive, hyperpolarization (∼5 mV), which is mediated by spike-dependent increases in pump activity. The duration of this dynamic pump potential is enhanced by dopamine. Our results therefore reveal sodium pumps as dynamic regulators of mammalian spinal motor networks that can also be affected by neuromodulatory systems. Given the involvement of sodium pumps in movement disorders, such as amyotrophic lateral sclerosis and rapid-onset dystonia parkinsonism, knowledge of their contribution to motor network regulation also has considerable clinical importance. SIGNIFICANCE STATEMENT The sodium pump is ubiquitously expressed and responsible for at least half of total brain energy consumption. The pumps maintain ionic gradients and the resting membrane potential of neurons, but increasing evidence suggests that activity- and state-dependent changes in pump activity also influence neuronal firing. Here we demonstrate that changes in sodium pump activity regulate locomotor output in the spinal cord of neonatal mice. We describe a sodium pump-mediated afterhyperpolarization in spinal neurons, mediated by spike-dependent increases in pump activity, which is affected by dopamine. Understanding how sodium pumps contribute to network regulation and are targeted by neuromodulators, including dopamine, has clinical relevance due to the role of the sodium pump in diseases, including amyotrophic lateral sclerosis, parkinsonism, epilepsy, and hemiplegic migraine. PMID:28123025

Polarization of the induced THz emission of donors in silicon

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kovalevsky, K. A., E-mail: atan4@yandex.ru; Zhukavin, R. Kh.; Tsyplenkov, V. V.

2016-12-15

The polarization of the terahertz (4.9–6.4 THz) stimulated emission of Group-V (Sb, P, As, Bi) donors in single-crystal silicon under pumping (photoionization) by a CO{sub 2} laser (photon energy 117 meV), depending on the uniaxial compressive deformation of the crystal along the [100] axis, is experimentally investigated. The influence of the field direction of the pump wave on its efficiency is discussed.

Optimization of end-pumped, actively Q-switched quasi-III-level lasers.

PubMed

Jabczynski, Jan K; Gorajek, Lukasz; Kwiatkowski, Jacek; Kaskow, Mateusz; Zendzian, Waldemar

2011-08-15

The new model of end-pumped quasi-III-level laser considering transient pumping processes, ground-state-depletion and up-conversion effects was developed. The model consists of two parts: pumping stage and Q-switched part, which can be separated in a case of active Q-switching regime. For pumping stage the semi-analytical model was developed, enabling the calculations for final occupation of upper laser level for given pump power and duration, spatial profile of pump beam, length and dopant level of gain medium. For quasi-stationary inversion, the optimization procedure of Q-switching regime based on Lagrange multiplier technique was developed. The new approach for optimization of CW regime of quasi-three-level lasers was developed to optimize the Q-switched lasers operating with high repetition rates. Both methods of optimizations enable calculation of optimal absorbance of gain medium and output losses for given pump rate. © 2011 Optical Society of America

Surgery and proton pump inhibitors for treatment of vocal process granulomas.

PubMed

Hong-Gang, Duan; He-Juan, Jin; Chun-Quan, Zheng; Guo-Kang, Fan

2013-11-01

The aim of this study was to analyze the outcomes of vocal process granulomas treated with surgery and proton pump inhibitors and to specify related factors of recurrence. The medical records of patients with diagnosis of vocal process granuloma between 2000 and 2012 were reviewed. All patients were treated with surgery and proton pump inhibitors for at least 1 month. Forty-one patients were reviewed; mean follow-up time was 45 months. There was no recurrence among the patients who had a recent history of intubation. The recurrence rates of contact granuloma was 38.7 %, and significantly related to the frequency of surgery (P = 0.042), but was not significantly associated with the history of acid reflux (P = 0.676) and vocal abuse (P = 0.447), lesion size (P = 0.203) or surgical techniques (P = 0.331). Surgery combined with proton pump inhibitors was partially effective for the vocal process granulomas, especially with intubated patients. However, repeat surgery for recurrent contact granuloma should be preceded with caution due to high recurrence rates.

Simulation of deleterious processes in a static-cell diode pumped alkali laser

NASA Astrophysics Data System (ADS)

Oliker, Benjamin Q.; Haiducek, John D.; Hostutler, David A.; Pitz, Greg A.; Rudolph, Wolfgang; Madden, Timothy J.

2014-02-01

The complex interactions in a diode pumped alkali laser (DPAL) gain cell provide opportunities for multiple deleterious processes to occur. Effects that may be attributable to deleterious processes have been observed experimentally in a cesium static-cell DPAL at the United States Air Force Academy [B.V. Zhdanov, J. Sell, R.J. Knize, "Multiple laser diode array pumped Cs laser with 48 W output power," Electronics Letters, 44, 9 (2008)]. The power output in the experiment was seen to go through a "roll-over"; the maximum power output was obtained with about 70 W of pump power, then power output decreased as the pump power was increased beyond this point. Research to determine the deleterious processes that caused this result has been done at the Air Force Research Laboratory utilizing physically detailed simulation. The simulations utilized coupled computational fluid dynamics (CFD) and optics solvers, which were three-dimensional and time-dependent. The CFD code used a cell-centered, conservative, finite-volume discretization of the integral form of the Navier-Stokes equations. It included thermal energy transport and mass conservation, which accounted for chemical reactions and state kinetics. Optical models included pumping, lasing, and fluorescence. The deleterious effects investigated were: alkali number density decrease in high temperature regions, convective flow, pressure broadening and shifting of the absorption lineshape including hyperfine structure, radiative decay, quenching, energy pooling, off-resonant absorption, Penning ionization, photoionization, radiative recombination, three-body recombination due to free electron and buffer gas collisions, ambipolar diffusion, thermal aberration, dissociative recombination, multi-photon ionization, alkali-hydrocarbon reactions, and electron impact ionization.

77 FR 2957 - Application for Manufacturing Authority, Liberty Pumps, Inc. (Submersible and Water Pumps...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-20

..., mechanical seals, electric motors, transformers, capacitors, switches, electronic components, integrated circuits, process controllers, printed circuit assemblies, electrical components, and measuring instruments...