Empirical Analysis and Refinement of Expert System Knowledge Bases

DTIC Science & Technology

1990-03-31

the number of hidden units and the error rates is listed in Figure 6. 3.3. Cancer Data A data qet for eva!ukting th.- Frognosis of breast cancer ...Alternative Rule Induction Methods A data set for evaluating the prognosis of breast cancer recurrence was analyzed by Michalski’s AQI5 rule induction program...AQ15 7 2 32% PVM 2 1 23% Figure 6-3: Comparative Summa-y for AQI5 and PVM on Breast Cancer Data 6.2.2. Alternative Decision Tree Induction Methods

Detection of a pneumonia virus of mice (PVM) in an African hedgehog (Atelerix arbiventris) with suspected wobbly hedgehog syndrome (WHS).

PubMed

Madarame, Hiroo; Ogihara, Kikumi; Kimura, Moe; Nagai, Makoto; Omatsu, Tsutomu; Ochiai, Hideharu; Mizutani, Tetsyuya

2014-09-17

A pneumonia virus of mice (PVM) from an African hedgehog (Atelerix arbiventris) with suspected wobbly hedgehog syndrome (WHS) was detected and genetically characterized. The affected hedgehog had a nonsuppurative encephalitis with vacuolization of the white matter, and the brain samples yielded RNA reads highly homogeneous to PVM strain 15 (96.5% of full genomic sequence homology by analysis of next generation sequencing). PVM antigen was also detected in the brain and the lungs immunohistochemically. A PVM was strongly suggested as a causative agent of encephalitis of a hedgehog with suspected WHS. This is a first report of PVM infection in hedgehogs. Copyright © 2014 Elsevier B.V. All rights reserved.

Crocodilian perivitelline membrane-bound sperm detection.

PubMed

Augustine, Lauren

2017-05-01

Advanced reproductive technologies (ART's) are often employed with various taxa to enhance captive breeding programs and maintain genetic diversity. Perivitelline membrane-bound (PVM-bound) sperm detection has previously been demonstrated in avian and chelonian species as a useful technique for breeding management. In the absence of embryotic development within an egg, this technique can detect the presence of sperm trapped on the oocyte membrane confirming breeding, male reproductive status, and pair compatibility. PVM-bound sperm were successfully detected in three clutches of Cuban crocodile (Crocodylus rhombifer) eggs at the Smithsonian's National Zoological Park (NZP) for the first time in any crocodilian species. PVM-bound sperm were detected in fresh and incubated C. rhombifer eggs, as well as eggs that were developing (banded) and those that were not (not banded). The results of this study showed significant differences in average sperm densities per egg between clutches (p = 0.001). Additionally, there was not a significant difference within clutches between eggs that banded and those that did not band (Clutch A, p = 0.505; Clutch B, p = 0.665; Clutch C, p = 0.266). The results of this study demonstrate the necessity to microscopically examine eggs that do not develop (do not band), to determine if sperm is present, which can help animal managers problem solve reproductive shortcomings. PVM-bound sperm detection could be a useful technique in assessing crocodilian breeding programs, as well as have potential uses in studies assessing sperm storage, artificial insemination, and artificial incubation. This article is a U.S. Government work and is in the public domain in the USA.

Optimized and parallelized implementation of the electronegativity equalization method and the atom-bond electronegativity equalization method.

PubMed

Vareková, R Svobodová; Koca, J

2006-02-01

The most common way to calculate charge distribution in a molecule is ab initio quantum mechanics (QM). Some faster alternatives to QM have also been developed, the so-called "equalization methods" EEM and ABEEM, which are based on DFT. We have implemented and optimized the EEM and ABEEM methods and created the EEM SOLVER and ABEEM SOLVER programs. It has been found that the most time-consuming part of equalization methods is the reduction of the matrix belonging to the equation system generated by the method. Therefore, for both methods this part was replaced by the parallel algorithm WIRS and implemented within the PVM environment. The parallelized versions of the programs EEM SOLVER and ABEEM SOLVER showed promising results, especially on a single computer with several processors (compact PVM). The implemented programs are available through the Web page http://ncbr.chemi.muni.cz/~n19n/eem_abeem.

Brain perivascular macrophages: characterization and functional roles in health and disease.

PubMed

Faraco, Giuseppe; Park, Laibaik; Anrather, Josef; Iadecola, Costantino

2017-11-01

Perivascular macrophages (PVM) are a distinct population of resident brain macrophages characterized by a close association with the cerebral vasculature. PVM migrate from the yolk sac into the brain early in development and, like microglia, are likely to be a self-renewing cell population that, in the normal state, is not replenished by circulating monocytes. Increasing evidence implicates PVM in several disease processes, ranging from brain infections and immune activation to regulation of the hypothalamic-adrenal axis and neurovascular-neurocognitive dysfunction in the setting of hypertension, Alzheimer disease pathology, or obesity. These effects involve crosstalk between PVM and cerebral endothelial cells, interaction with circulating immune cells, and/or production of reactive oxygen species. Overall, the available evidence supports the idea that PVM are a key component of the brain-resident immune system with broad implications for the pathogenesis of major brain diseases. A better understanding of the biology and pathobiology of PVM may lead to new insights and therapeutic strategies for a wide variety of brain diseases.

Thermal control system for Space Station Freedom photovoltaic power module

NASA Technical Reports Server (NTRS)

Hacha, Thomas H.; Howard, Laura

1994-01-01

The electric power for Space Station Freedom (SSF) is generated by the solar arrays of the photovoltaic power modules (PVM's) and conditioned, controlled, and distributed by a power management and distribution system. The PVM's are located outboard of the alpha gimbals of SSF. A single-phase thermal control system is being developed to provide thermal control of PVM electrical equipment and energy storage batteries. This system uses ammonia as the coolant and a direct-flow deployable radiator. The description and development status of the PVM thermal control system is presented.

Thermal control system for Space Station Freedom photovoltaic power module

NASA Technical Reports Server (NTRS)

Hacha, Thomas H.; Howard, Laura S.

1992-01-01

The electric power for Space Station Freedom (SSF) is generated by the solar arrays of the photovoltaic power modules (PVM's) and conditioned, controlled, and distributed by a power management and distribution system. The PVM's are located outboard of the alpha gimbals of SSF. A single-phase thermal control system is being developed to provide thermal control of PVM electrical equipment and energy storage batteries. This system uses ammonia as the coolant and a direct-flow deployable radiator. This paper presents the description and development status of the PVM thermal control system.

Laboratory Investigation of Direct Measurement of Ice Water Content, Ice Surface Area, and Effective Radius of Ice Crystals Using a Laser-Diffraction Instrument

NASA Technical Reports Server (NTRS)

Gerber, H.; DeMott, P. J.; Rogers, D. C.

1995-01-01

The aircraft microphysics probe, PVM-100A, was tested in the Colorado State University dynamic cloud chamber to establish its ability to measure ice water content (IWC), PSA, and Re in ice clouds. Its response was compared to other means of measuring those ice-cloud parameters that included using FSSP-100 and 230-X 1-D optical probes for ice-crystal concentrations, a film-loop microscope for ice-crystal habits and dimensions, and an in-situ microscope for determining ice-crystal orientation. Intercomparisons were made in ice clouds containing ice crystals ranging in size from about 10 microns to 150 microns diameter, and ice crystals with plate, columnar, dendritic, and spherical shapes. It was not possible to determine conclusively that the PVM accurately measures IWC, PSA, and Re of ice crystals, because heat from the PVM evaporated in part the crystals in its vicinity in the chamber thus affecting its measurements. Similarities in the operating principle of the FSSP and PVM, and a comparison between Re measured by both instruments, suggest, however, that the PVM can make those measurements. The resolution limit of the PVM for IWC measurements was found to be on the order of 0.001 g/cubic m. Algorithms for correcting IWC measured by FSSP and PVM were developed.

The Pedagogical Variation Model (PVM) for Work-Based Training in Virtual Classrooms: Evaluation at Kuwait University

ERIC Educational Resources Information Center

Rogers, Maria Susy; Aldhafeeri, Fayiz Mensher

2015-01-01

A collaborative research initiative was undertaken to evaluate the pedagogical variation model (PVM) for online learning and teaching at Kuwait University. Outcomes from sample populations of students--both postgraduates and undergraduates--from the Faculty of Education were analyzed for comparison. As predicted in the PVM, the findings indicate…

Preparation of Poly-(Methyl vinyl ether-co-maleic Anhydride) Nanoparticles by Solution-Enhanced Dispersion by Supercritical CO2

PubMed Central

Chen, Ai-Zheng; Wang, Guang-Ya; Wang, Shi-Bin; Feng, Jian-Gang; Liu, Yuan-Gang; Kang, Yong-Qiang

2012-01-01

The supercritical CO2-based technologies have been widely used in the formation of drug and/or polymer particles for biomedical applications. In this study, nanoparticles of poly-(methyl vinyl ether-co-maleic anhydride) (PVM/MA) were successfully fabricated by a process of solution-enhanced dispersion by supercritical CO2 (SEDS). A 23 factorial experiment was designed to investigate and identify the significance of the processing parameters (concentration, flow and solvent/nonsolvent) for the surface morphology, particle size, and particle size distribution of the products. The effect of the concentration of PVM/MA was found to be dominant in the results regarding particle size. Decreasing the initial solution concentration of PVM/MA decreased the particle size significantly. After optimization, the resulting PVM/MA nanoparticles exhibited a good spherical shape, a smooth surface, and a narrow particle size distribution. Fourier transform infrared spectroscopy (FTIR) spectra demonstrated that the chemical composition of PVM/MA was not altered during the SEDS process and that the SEDS process was therefore a typical physical process. The absolute value of zeta potential of the obtained PVM/MA nanoparticles was larger than 40 mV, indicating the samples’ stability in aqueous suspension. Analysis of thermogravimetry-differential scanning calorimetry (TG-DSC) revealed that the effect of the SEDS process on the thermostability of PVM/MA was negligible. The results of gas chromatography (GC) analysis confirmed that the SEDS process could efficiently remove the organic residue.

The use of portable video media vs standard verbal communication in the urological consent process: a multicentre, randomised controlled, crossover trial.

PubMed

Winter, Matthew; Kam, Jonathan; Nalavenkata, Sunny; Hardy, Ellen; Handmer, Marcus; Ainsworth, Hannah; Lee, Wai Gin; Louie-Johnsun, Mark

2016-11-01

To determine if portable video media (PVM) improves patient's knowledge and satisfaction acquired during the consent process for cystoscopy and insertion of a ureteric stent compared to standard verbal communication (SVC), as informed consent is a crucial component of patient care and PVM is an emerging technology that may help improve the consent process. In this multi-centre randomised controlled crossover trial, patients requiring cystoscopy and stent insertion were recruited from two major teaching hospitals in Australia over a 15-month period (July 2014-December 2015). Patient information delivery was via PVM and SVC. The PVM consisted of an audio-visual presentation with cartoon animation presented on an iPad. Patient satisfaction was assessed using the validated Client Satisfaction Questionnaire 8 (CSQ-8; maximum score 32) and knowledge was tested using a true/false questionnaire (maximum score 28). Questionnaires were completed after first intervention and after crossover. Scores were analysed using the independent samples t-test and Wilcoxon signed-rank test for the crossover analysis. In all, 88 patients were recruited. A significant 3.1 point (15.5%) increase in understanding was demonstrable favouring the use of PVM (P < 0.001). There was no difference in patient satisfaction between the groups as judged by the CSQ-8. A significant 3.6 point (17.8%) increase in knowledge score was seen when the SVC group were crossed over to the PVM arm. A total of 80.7% of patients preferred PVM and 19.3% preferred SVC. Limitations include the lack of a validated questionnaire to test knowledge acquired from the interventions. This study demonstrates patients' preference towards PVM in the urological consent process of cystoscopy and ureteric stent insertion. PVM improves patient's understanding compared with SVC and is a more effective means of content delivery to patients in terms of overall preference and knowledge gained during the consent process. © 2016 The Authors BJU International © 2016 BJU International Published by John Wiley & Sons Ltd.

A heterogeneous computing environment for simulating astrophysical fluid flows

NASA Technical Reports Server (NTRS)

Cazes, J.

1994-01-01

In the Concurrent Computing Laboratory in the Department of Physics and Astronomy at Louisiana State University we have constructed a heterogeneous computing environment that permits us to routinely simulate complicated three-dimensional fluid flows and to readily visualize the results of each simulation via three-dimensional animation sequences. An 8192-node MasPar MP-1 computer with 0.5 GBytes of RAM provides 250 MFlops of execution speed for our fluid flow simulations. Utilizing the parallel virtual machine (PVM) language, at periodic intervals data is automatically transferred from the MP-1 to a cluster of workstations where individual three-dimensional images are rendered for inclusion in a single animation sequence. Work is underway to replace executions on the MP-1 with simulations performed on the 512-node CM-5 at NCSA and to simultaneously gain access to more potent volume rendering workstations.

HeNCE: A Heterogeneous Network Computing Environment

DOE PAGES

Beguelin, Adam; Dongarra, Jack J.; Geist, George Al; ...

1994-01-01

Network computing seeks to utilize the aggregate resources of many networked computers to solve a single problem. In so doing it is often possible to obtain supercomputer performance from an inexpensive local area network. The drawback is that network computing is complicated and error prone when done by hand, especially if the computers have different operating systems and data formats and are thus heterogeneous. The heterogeneous network computing environment (HeNCE) is an integrated graphical environment for creating and running parallel programs over a heterogeneous collection of computers. It is built on a lower level package called parallel virtual machine (PVM).more » The HeNCE philosophy of parallel programming is to have the programmer graphically specify the parallelism of a computation and to automate, as much as possible, the tasks of writing, compiling, executing, debugging, and tracing the network computation. Key to HeNCE is a graphical language based on directed graphs that describe the parallelism and data dependencies of an application. Nodes in the graphs represent conventional Fortran or C subroutines and the arcs represent data and control flow. This article describes the present state of HeNCE, its capabilities, limitations, and areas of future research.« less

STUDIES ON PNEUMONIA VIRUS OF MICE (PVM) IN CELL CULTURE

PubMed Central

Harter, Donald H.; Choppin, Purnell W.

1967-01-01

Pneumonia virus of mice (PVM) has been serially propagated in a line of baby hamster kidney (BHK21) cells. A maximum titer of 6.3 x 106 TCID50 per ml was obtained, and there was little variation in yield on serial passage. PVM grown in BHK21 cells was antigenically similar to virus obtained from the mouse lung, but was somewhat less virulent for the mouse after 10 serial passages in these cells. Virus produced by BHK21 cells agglutinated mouse erythrocytes without prior heating or other treatment. Sedimentation of PVM in the ultracentrifuge or precipitation by ammonium sulfate resulted in a loss in infectivity but an increase in hemagglutinating activity, presumably due to disruption of the virus particle. In a potassium tartrate density gradient, the major portion of infective virus sedimented at a density of approximately 1.15, and noninfective hemagglutinin, at a density of approximately 1.13. Stock virus preparations appear to contain a large amount of noninfective hemagglutinin. The replication of PVM was not inhibited by 5-fluoro-2'-deoxyuridine, 5-bromo-2'-deoxyuridine, or 5-iodo-2'-deoxyuridine. Infected cells contained eosinophilic cytoplasmic inclusions which showed the acridine orange staining characteristic of single-stranded RNA. Foci of viral antigen were observed in the cytoplasm of infected cells by fluorescent antibody staining. The results suggest that PVM is an RNA virus that replicates in the cytoplasm. PMID:4165740

Molecular make-up of the Plasmodium parasitophorous vacuolar membrane.

PubMed

Spielmann, Tobias; Montagna, Georgina N; Hecht, Leonie; Matuschewski, Kai

2012-10-01

Plasmodium, the causative agent of malaria, is an obligate, intracellular, eukaryotic cell that invades, replicates, and differentiates within hepatocytes and erythrocytes. Inside a host cell, a second membrane delineates the developing pathogen in addition to the parasite plasma membrane, resulting in a distinct cellular compartment, termed parasitophorous vacuole (PV). The PV membrane (PVM) constitutes the parasite-host cell interface and is likely central to nutrient acquisition, host cell remodeling, waste disposal, environmental sensing, and protection from innate defense. Over the past two decades, a number of parasite-encoded PVM proteins have been identified. They include multigene families and protein complexes, such as early-transcribed membrane proteins (ETRAMPs) and the Plasmodium translocon for exported proteins (PTEX). Nearly all Plasmodium PVM proteins are restricted to this genus and display transient and stage-specific expression. Here, we provide an overview of the PVM proteins of Plasmodium blood and liver stages. Biochemical and experimental genetics data suggest that some PVM proteins are ideal targets for novel anti-malarial intervention strategies. Copyright © 2012 Elsevier GmbH. All rights reserved.

Metacomputing on Commodity Computers

DTIC Science & Technology

1999-05-01

on NOWs, and this has contributed to the popularity of systems such as PVM [59], MPI [67], Linda [33], and TreadMarks [2]. 26 Challenges Given that...presents the performance of Calypso and Persistent Linda (PLinda) [77] programs and compares how they can tolerate failures. A biological pattern...adds fault tolerance to Linda programs by using light-weight transac- tions, whereas Calypso uses the combination of eager scheduling and two-phase

DOE Office of Scientific and Technical Information (OSTI.GOV)

Glineur, Stephanie F.; Renshaw, Randall W.; Percopo, Caroline M.

A previous report of a novel pneumovirus (PnV) isolated from the respiratory tract of a dog described its significant homology to the rodent pathogen, pneumonia virus of mice (PVM). The original PnV–Ane4 pathogen replicated in and could be re-isolated in infectious state from mouse lung but elicited minimal mortality compared to PVM strain J3666. Here we assess phylogeny and physiologic responses to 10 new PnV isolates. The G/glycoprotein sequences of all PnVs include elongated amino-termini when compared to the characterized PVMs, and suggest division into groups A and B. While we observed significant differences in cytokine production and neutrophil recruitmentmore » to the lungs of BALB/c mice in response to survival doses (50 TCID{sub 50} units) of representative group A (114378-10-29-KY-F) and group B (7968-11-OK) PnVs, we observed no evidence for positive selection (dN>dS) among the PnV/PnV, PVM/PnV or PVM/PVM G/glycoprotein or F/fusion protein sequence pairs. - Highlights: • We consider ten novel isolates of the pneumovirus (PnV) first described by Renshaw and colleagues. • The G/glycoprotein sequences of all PnVs include elongated amino-termini when compared to PVM. • We detect cytokine production and neutrophil recruitment to the lungs of mice in response to PnV. • We observed no evidence for positive selection (dN>dS) among the gene sequence pairs.« less

Interactions between Multiple Genetic Determinants in the 5′ UTR and VP1 Capsid Control Pathogenesis of Chronic Post-Viral Myopathy caused by Coxsackievirus B1

PubMed Central

Sandager, Maribeth M.; Nugent, Jaime L.; Schulz, Wade L.; Messner, Ronald P.; Tam, Patricia E.

2008-01-01

Mice infected with coxsackievirus B1 Tucson (CVB1T) develop chronic, post-viral myopathy (PVM) with clinical manifestations of hind limb muscle weakness and myositis. The objective of the current study was to establish the genetic basis of myopathogenicity in CVB1T. Using a reverse genetics approach, full attenuation of PVM could only be achieved by simultaneously mutating four sites located at C706U in the 5′ untranslated region (5′ UTR) and at Y87F, V136A, and T276A in the VP1 capsid. Engineering these four myopathic determinants into an amyopathic CVB1T variant restored the ability to cause PVM. Moreover, these same four determinants controlled PVM expression in a second strain of mice, indicating that the underlying mechanism is operational in mice of different genetic backgrounds. Modeling studies predict that C706U alters both local and long-range pairing in the 5′ UTR, and that VP1 determinants are located on the capsid surface. However, these differences did not affect viral titers, temperature stability, pH stability, or the antibody response to virus. These studies demonstrate that PVM develops from a complex interplay between viral determinants in the 5′ UTR and VP1 capsid and have uncovered intriguing similarities between genetic determinants that cause PVM and those involved in pathogenesis of other enteroviruses. PMID:18029287

Heterogeneous concurrent computing with exportable services

NASA Technical Reports Server (NTRS)

Sunderam, Vaidy

1995-01-01

Heterogeneous concurrent computing, based on the traditional process-oriented model, is approaching its functionality and performance limits. An alternative paradigm, based on the concept of services, supporting data driven computation, and built on a lightweight process infrastructure, is proposed to enhance the functional capabilities and the operational efficiency of heterogeneous network-based concurrent computing. TPVM is an experimental prototype system supporting exportable services, thread-based computation, and remote memory operations that is built as an extension of and an enhancement to the PVM concurrent computing system. TPVM offers a significantly different computing paradigm for network-based computing, while maintaining a close resemblance to the conventional PVM model in the interest of compatibility and ease of transition Preliminary experiences have demonstrated that the TPVM framework presents a natural yet powerful concurrent programming interface, while being capable of delivering performance improvements of upto thirty percent.

Pneumonia Virus of Mice Severe Respiratory Virus Infection in a Natural Host

PubMed Central

Rosenberg, Helene F.; Domachowske, Joseph B.

2008-01-01

Pneumonia virus of mice (PVM; family Paramyxoviridae, genus Pneumovirus) is a natural mouse pathogen that is closely related to the human and bovine respiratory syncytial viruses. Among the prominent features of this infection, robust replication of PVM takes place in bronchial epithelial cells in response to a minimal virus inoculum. Virus replication in situ results in local production of proinflammatory cytokines (MIP-1α, MIP-2, MCP-1 and IFNγ) and granulocyte recruitment to the lung. If left unchecked, PVM infection and the ensuing inflammatory response ultimately lead to pulmonary edema, respiratory compromise and death. In this review, we consider the recent studies using the PVM model that have provided important insights into the role of the inflammatory response in the pathogenesis of severe respiratory virus infection. We also highlight several works that have elucidated acquired immune responses to this pathogen, including T cell responses and the development of humoral immunity. Finally, we consider several immunomodulatory strategies that have been used successfully to reduce morbidity and mortality when administered to PVM infected, symptomatic mice, and thus hold promise as realistic therapeutic strategies for severe respiratory virus infections in human subjects. PMID:18471897

Final report of PVM-6 and PVM-7 Weather Documentation, AFCRL/Minuteman Report Number 6

DTIC Science & Technology

1975-09-11

Research Laboratories, Hanscon AFB, MA 01731. USAFGL ltr, 1 Aug 1983 TH!3 R~PORT HAS BEEN DELIMI~ED AND CLtARED FOR PUBLIC REL~5E UNDER DOP DiRECTIVE...5200.20 AND NO RESTniCTIONS ARE IMPDSED UPON r rs usE P.ND n 1 scu1sURI:. DISTRIBUTION STATE~ENT A APPROVED FQR PUBLIC RELEASE; DISTRIBUTION...NO AFCRL -TR-75 -04817^ F C ^ I - 1 ^T" 1 . » " 3^ 3 / *■ TlTUSfltf fidUtUlt- JINAL REPORT OFPyM-6 AND PVM-7 WEATHER DOCUMENTATION^ | AFCRl

Non-Traumatic Myositis Ossificans in the Lumbosacral Paravertebral Muscle

PubMed Central

Jung, DaeYoung; Roh, Ji Hyeon

2013-01-01

Myositis ossificans (MO) is a benign condition of non-neoplastic heterotopic bone formation in the muscle or soft tissue. Trauma plays a role in the development of MO, thus, non-traumatic MO is very rare. Although MO may occur anywhere in the body, it is rarely seen in the lumbosacral paravertebral muscle (PVM). Herein, we report a case of non-traumatic MO in the lumbosacral PVM. A 42-year-old man with no history of trauma was referred to our hospital for pain in the low back, left buttock, and left thigh. On physical examination, a slightly tender, hard, and fixed mass was palpated in the left lumbosacral PVM. Computed tomography showed a calcified mass within the left lumbosacral PVM. Magnetic resonance imaging (MRI) showed heterogeneous high signal intensity in T1- and T2-weighted image, and no enhancement of the mass was found in the postcontrast T1-weighted MRI. The lack of typical imaging features required an open biopsy, and MO was confirmed. MO should be considered in the differential diagnosis when the imaging findings show a mass involving PVM. When it is difficult to distinguish MO from soft tissue or bone malignancy by radiology, it is necessary to perform a biopsy to confirm the diagnosis. PMID:23908707

Test of prototype liquid-water-content meter for aircraft use

NASA Technical Reports Server (NTRS)

Gerber, Hermann E.

1993-01-01

This report describes the effort undertaken to meet the objectives of National Science Foundation Grant ATM-9207345 titled 'Test of Prototype Liquid-Water-Content Meter for Aircraft Use.' Three activities were proposed for testing the new aircraft instrument, PVM-100A: (1) Calibrate the PVM-100A in a facility where the liquid-water-content (LWC) channel, and the integrated surface area channel (PSA) could be compared to standard means for LWC and PSA measurements. Scaling constant for the channels were to be determined in this facility. The fog/wind tunnel at ECN, Petten, The Netherlands was judged the most suitable facility for this effort. (2) Expose the PVM-100A to high wind speeds similar to those expected on research aircraft, and test the anti-icing heaters on the PVM-100A under typical icing conditions expected in atmospheric clouds. The high-speed icing tunnel at NRC, Ottawa, Canada was to be utilized. (3) Operate the PVM-100A on an aircraft during cloud penetrations to determine its stability and practicality for such measurements. The C-131A aircraft of the University of Washington was the aircraft of opportunity for these-tests, which were to be conducted during the 4-week Atlantic Stratocumulus Transition Experiment (ASTEX) in June of 1992.

On the anatomy and histology of the pubovisceral muscle enthesis in women.

PubMed

Kim, Jinyong; Ramanah, Rajeev; DeLancey, John O L; Ashton-Miller, James A

2011-09-01

The origin of the pubovisceral muscle (PVM) from the pubic bone is known to be at elevated risk for injury during difficult vaginal births. We examined the anatomy and histology of its enthesial origin to classify its type and see if it differs from appendicular entheses. Parasagittal sections of the pubic bone, PVM enthesis, myotendinous junction, and muscle proper were harvested from five female cadavers (51-98 years). Histological sections were prepared with hematoxylin and eosin, Masson's trichrome, and Verhoeff-Van Gieson stains. The type of enthesis was identified according to a published enthesial classification scheme. Quantitative imaging analysis was performed in sampling bands 2 mm apart along the enthesis to determine its cross-sectional area and composition. The PVM enthesis can be classified as a fibrous enthesis. The PVM muscle fibers terminated in collagenous fibers that insert tangentially onto the periosteum of the pubic bone for the most part. Sharpey's fibers were not observed. In a longitudinal cross-section, the area of the connective tissue and muscle becomes equal approximately 8 mm from the pubic bone. The PVM originates bilaterally from the pubic bone via fibrous entheses whose collagen fibers arise tangentially from the periosteum of the pubic bone. Copyright © 2010 Wiley-Liss, Inc.

On the Anatomy and Histology of the Pubovisceral Muscle Enthesis in Women

PubMed Central

Kim, Jinyong; Ramanah, Rajeev; DeLancey, John O. L.; Ashton-Miller, James A.

2012-01-01

Aims The origin of the pubovisceral muscle (PVM) from the pubic bone is known to be at elevated risk for injury during difficult vaginal births. We examined the anatomy and histology of its enthesial origin to classify its type and see if it differs from appendicular entheses. Methods Parasagittal sections of the pubic bone, PVM enthesis, myotendinous junction and muscle proper were harvested from five female cadavers (51 - 98 years). Histological sections were prepared with hematoxylin and eosin, Masson’s trichrome, and Verhoeff-Van Gieson stains. The type of enthesis was identified according to a published enthesial classification scheme. Quantitative imaging analysis was performed in sampling bands 2 mm apart along the enthesis to determine its cross-sectional area and composition. Results The PVM enthesis can be classified as a fibrous enthesis. The PVM muscle fibers terminated in collagenous fibers that insert tangentially onto the periosteum of the pubic bone for the most part. Sharpey’s fibers were not observed. In a longitudinal cross-section, the area of the connective tissue and muscle becomes equal approximately 8 mm from the pubic bone. Conclusion The PVM originates bilaterally from the pubic bone via fibrous entheses whose collagen fibers arise tangentially from the periosteum of the pubic bone. PMID:21567449

Portable Video Media Versus Standard Verbal Communication in Surgical Information Delivery to Nurses: A Prospective Multicenter, Randomized Controlled Crossover Trial.

PubMed

Kam, Jonathan; Ainsworth, Hannah; Handmer, Marcus; Louie-Johnsun, Mark; Winter, Matthew

2016-10-01

Continuing education of health professionals is important for delivery of quality health care. Surgical nurses are often required to understand surgical procedures. Nurses need to be aware of the expected outcomes and recognize potential complications of such procedures during their daily work. Traditional educational methods, such as conferences and tutorials or informal education at the bedside, have many drawbacks for delivery of this information in a universal, standardized, and timely manner. The rapid uptake of portable media devices makes portable video media (PVM) a potential alternative to current educational methods. To compare PVM to standard verbal communication (SVC) for surgical information delivery and educational training for nurses and evaluate its impact on knowledge acquisition and participant satisfaction. Prospective, multicenter, randomized controlled crossover trial. Two hospitals: Gosford District Hospital and Wyong Hospital. Seventy-two nursing staff (36 at each site). Information delivery via PVM--7-minute video compared to information delivered via SVC. Knowledge acquisition was measured by a 32-point questionnaire, and satisfaction with the method of education delivery was measured using the validated Client Satisfaction Questionnaire (CSQ-8). Knowledge acquisition was higher via PVM compared to SVC 25.9 (95% confidence interval [CI] 25.2-26.6) versus 24.3 (95% CI 23.5-25.1), p = .004. Participant satisfaction was higher with PVM 29.5 (95% CI 28.3-30.7) versus 26.5 (95% CI 25.1-27.9), p = .003. Following information delivery via SVC, participants had a 6% increase in knowledge scores, 24.3 (95% CI 23.5-25.1) versus 25.7 (95% CI 24.9-26.5) p = .001, and a 13% increase in satisfaction scores, 26.5 (95% CI 25.1-27.9) versus 29.9 (95% CI 28.8-31.0) p < .001, when they crossed-over to information delivery via PVM. PVM provides a novel method for providing education to nurses that improves knowledge retention and satisfaction with the educational process. © 2016 Sigma Theta Tau International.

Model institutional infrastructures for recycling of photovoltaic modules

DOE Office of Scientific and Technical Information (OSTI.GOV)

Reaven, S.J.; Moskowitz, P.D.; Fthenakis, V.

1996-01-01

How will photovoltaic modules (PVMS) be recycled at the end of their service lives? This question has technological and institutional components (Reaven, 1994a). The technological aspect concerns the physical means of recycling: what advantages and disadvantages of the several existing and emerging mechanical, thermal, and chemical recycling processes and facilities merit consideration? The institutional dimension refers to the arrangements for recycling: what are the operational and financial roles of the parties with an interest in PVM recycling? These parties include PVM manufacturers, trade organizations; distributors, and retailers; residential, commercial, and utility PVM users; waste collectors, transporters, reclaimers, and reclaimers; andmore » governments.« less

Intranasal treatment with a novel immunomodulator mediates innate immune protection against lethal pneumonia virus of mice.

PubMed

Martinez, Elisa C; Garg, Ravendra; Shrivastava, Pratima; Gomis, Susantha; van Drunen Littel-van den Hurk, Sylvia

2016-11-01

Respiratory syncytial virus (RSV) is the leading cause of acute lower respiratory tract infections in infants and young children. There are no licensed RSV vaccines available, and the few treatment options for high-risk individuals are either extremely costly or cause severe side effects and toxicity. Immunomodulation mediated by a novel formulation consisting of the toll-like receptor 3 agonist poly(I:C), an innate defense regulator peptide and a polyphosphazene (P-I-P) was evaluated in the context of lethal infection with pneumonia virus of mice (PVM). Intranasal delivery of a single dose of P-I-P protected adult mice against PVM when given 24 h prior to challenge. These animals experienced minimal weight loss, no clinical disease, 100% survival, and reduced lung pathology. Similar clinical outcomes were observed in mice treated up to 3 days prior to infection. P-I-P pre-treatment induced early mRNA and protein expression of key chemokine and cytokine genes, reduced the recruitment of neutrophils and eosinophils, decreased virus titers in the lungs, and modulated the delayed exacerbated nature of PVM disease without any short-term side effects. On day 14 post-infection, P-I-P-treated mice were confirmed to be PVM-free. These results demonstrate the capacity of this formulation to prevent PVM and possibly other viral respiratory infections. Copyright © 2016 Elsevier B.V. All rights reserved.

High Performance Programming Using Explicit Shared Memory Model on the Cray T3D

NASA Technical Reports Server (NTRS)

Saini, Subhash; Simon, Horst D.; Lasinski, T. A. (Technical Monitor)

1994-01-01

The Cray T3D is the first-phase system in Cray Research Inc.'s (CRI) three-phase massively parallel processing program. In this report we describe the architecture of the T3D, as well as the CRAFT (Cray Research Adaptive Fortran) programming model, and contrast it with PVM, which is also supported on the T3D We present some performance data based on the NAS Parallel Benchmarks to illustrate both architectural and software features of the T3D.

Shared elements of host-targeting pathways among apicomplexan parasites of differing lifestyles.

PubMed

Pellé, Karell G; Jiang, Rays H Y; Mantel, Pierre-Yves; Xiao, Yu-Ping; Hjelmqvist, Daisy; Gallego-Lopez, Gina M; O T Lau, Audrey; Kang, Byung-Ho; Allred, David R; Marti, Matthias

2015-11-01

Apicomplexans are a diverse group of obligate parasites occupying different intracellular niches that require modification to meet the needs of the parasite. To efficiently manipulate their environment, apicomplexans translocate numerous parasite proteins into the host cell. Whereas some parasites remain contained within a parasitophorous vacuole membrane (PVM) throughout their developmental cycle, others do not, a difference that affects the machinery needed for protein export. A signal-mediated pathway for protein export into the host cell has been characterized in Plasmodium parasites, which maintain the PVM. Here, we functionally demonstrate an analogous host-targeting pathway involving organellar staging prior to secretion in the related bovine parasite, Babesia bovis, a parasite that destroys the PVM shortly after invasion. Taking into account recent identification of a similar signal-mediated pathway in the coccidian parasite Toxoplasma gondii, we suggest a model in which this conserved pathway has evolved in multiple steps from signal-mediated trafficking to specific secretory organelles for controlled secretion to a complex protein translocation process across the PVM. © 2015 John Wiley & Sons Ltd.

Dust Dynamics in Protoplanetary Disks: Parallel Computing with PVM

NASA Astrophysics Data System (ADS)

de La Fuente Marcos, Carlos; Barge, Pierre; de La Fuente Marcos, Raúl

2002-03-01

We describe a parallel version of our high-order-accuracy particle-mesh code for the simulation of collisionless protoplanetary disks. We use this code to carry out a massively parallel, two-dimensional, time-dependent, numerical simulation, which includes dust particles, to study the potential role of large-scale, gaseous vortices in protoplanetary disks. This noncollisional problem is easy to parallelize on message-passing multicomputer architectures. We performed the simulations on a cache-coherent nonuniform memory access Origin 2000 machine, using both the parallel virtual machine (PVM) and message-passing interface (MPI) message-passing libraries. Our performance analysis suggests that, for our problem, PVM is about 25% faster than MPI. Using PVM and MPI made it possible to reduce CPU time and increase code performance. This allows for simulations with a large number of particles (N ~ 105-106) in reasonable CPU times. The performances of our implementation of the pa! rallel code on an Origin 2000 supercomputer are presented and discussed. They exhibit very good speedup behavior and low load unbalancing. Our results confirm that giant gaseous vortices can play a dominant role in giant planet formation.

Generalization of soft phonon modes

NASA Astrophysics Data System (ADS)

Rudin, Sven P.

2018-04-01

Soft phonon modes describe a collective movement of atoms that transform a higher-symmetry crystal structure into a lower-symmetry crystal structure. Such structural transformations occur at finite temperatures, where the phonons (i.e., the low-temperature vibrational modes) and the static perfect crystal structures provide an incomplete picture of the dynamics. Here, principal vibrational modes (PVMs) are introduced as descriptors of the dynamics of a material system with N atoms. The PVMs represent the independent collective movements of the atoms at a given temperature. Molecular dynamics (MD) simulations, here in the form of quantum MD using density functional theory calculations, provide both the data describing the atomic motion and the data used to construct the PVMs. The leading mode, PVM0, represents the 3 N -dimensional direction in which the system moves with greatest amplitude. For structural phase transitions, PVM0 serves as a generalization of soft phonon modes. At low temperatures, PVM0 reproduces the soft phonon mode in systems where one phonon dominates the phase transformation. In general, multiple phonon modes combine to describe a transformation, in which case PVM0 culls these phonon modes. Moreover, while soft phonon modes arise in the higher-symmetry crystal structure, PVM0 can be equally well calculated on either side of the structural phase transition. Two applications demonstrate these properties: first, transitions into and out of bcc titanium, and, second, the two crystal structures proposed for the β phase of uranium, the higher-symmetry structure of which stabilizes with temperature.

Preparation of Chitosan-Based Hemostatic Sponges by Supercritical Fluid Technology

PubMed Central

Song, Hu-Fan; Chen, Ai-Zheng; Wang, Shi-Bin; Kang, Yong-Qiang; Ye, Shi-Fu; Liu, Yuan-Gang; Wu, Wen-Guo

2014-01-01

Using ammonium bicarbonate (AB) particles as a porogen, chitosan (CS)-based hemostatic porous sponges were prepared in supercritical carbon dioxide due to its low viscosity, small surface tension, and good compatibility with organic solvent. Fourier transform infrared spectroscopy (FTIR) spectra demonstrated that the chemical compositions of CS and poly-(methyl vinyl ether-co-maleic anhydride) (PVM/MA) were not altered during the phase inversion process. The morphology and structure of the sponge after the supercritical fluid (SCF) process were observed by scanning electron microscopy (SEM). The resulting hemostatic sponges showed a relatively high porosity (about 80%) with a controllable pore size ranging from 0.1 to 200 μm. The concentration of PVM/MA had no significant influence on the porosity of the sponges. Comparative experiments on biological assessment and hemostatic effect between the resulting sponges and Avitene® were also carried out. With the incorporation of PVM/MA into the CS-based sponges, the water absorption rate of the sponges increased significantly, and the CS-PVM/MA sponges showed a similar water absorption rate (about 90%) to that of Avitene®. The results of the whole blood clotting experiment and animal experiment also demonstrated that the clotting ability of the CS-PVM/MA sponges was similar to that of Avitene®. All these results elementarily verified that the sponges prepared in this study were suitable for hemostasis and demonstrated the feasibility of using SCF-assisted phase inversion technology to produce hemostatic porous sponges. PMID:28788577

Animal model of respiratory syncytial virus: CD8+ T cells cause a cytokine storm that is chemically tractable by sphingosine-1-phosphate 1 receptor agonist therapy.

PubMed

Walsh, Kevin B; Teijaro, John R; Brock, Linda G; Fremgen, Daniel M; Collins, Peter L; Rosen, Hugh; Oldstone, Michael B A

2014-06-01

The cytokine storm is an intensified, dysregulated, tissue-injurious inflammatory response driven by cytokine and immune cell components. The cytokine storm during influenza virus infection, whereby the amplified innate immune response is primarily responsible for pulmonary damage, has been well characterized. Now we describe a novel event where virus-specific T cells induce a cytokine storm. The paramyxovirus pneumonia virus of mice (PVM) is a model of human respiratory syncytial virus (hRSV). Unexpectedly, when C57BL/6 mice were infected with PVM, the innate inflammatory response was undetectable until day 5 postinfection, at which time CD8(+) T cells infiltrated into the lung, initiating a cytokine storm by their production of gamma interferon (IFN-γ) and tumor necrosis factor alpha (TNF-α). Administration of an immunomodulatory sphingosine-1-phosphate (S1P) receptor 1 (S1P1R) agonist significantly inhibited PVM-elicited cytokine storm by blunting the PVM-specific CD8(+) T cell response, resulting in diminished pulmonary disease and enhanced survival. A dysregulated overly exuberant immune response, termed a "cytokine storm," accompanies virus-induced acute respiratory diseases (VARV), is primarily responsible for the accompanying high morbidity and mortality, and can be controlled therapeutically in influenza virus infection of mice and ferrets by administration of sphingosine-1-phosphate 1 receptor (S1P1R) agonists. Here, two novel findings are recorded. First, in contrast to influenza infection, where the cytokine storm is initiated early by the innate immune system, for pneumonia virus of mice (PVM), a model of RSV, the cytokine storm is initiated late in infection by the adaptive immune response: specifically, by virus-specific CD8 T cells via their release of IFN-γ and TNF-α. Blockading these cytokines with neutralizing antibodies blunts the cytokine storm and protects the host. Second, PVM infection is controlled by administration of an S1P1R agonist.

A Systems Engineering Framework for Implementing a Security and Critical Patch Management Process in Diverse Environments (Academic Departments' Workstations)

NASA Astrophysics Data System (ADS)

Mohammadi, Hadi

Use of the Patch Vulnerability Management (PVM) process should be seriously considered for any networked computing system. The PVM process prevents the operating system (OS) and software applications from being attacked due to security vulnerabilities, which lead to system failures and critical data leakage. The purpose of this research is to create and design a Security and Critical Patch Management Process (SCPMP) framework based on Systems Engineering (SE) principles. This framework will assist Information Technology Department Staff (ITDS) to reduce IT operating time and costs and mitigate the risk of security and vulnerability attacks. Further, this study evaluates implementation of the SCPMP in the networked computing systems of an academic environment in order to: 1. Meet patch management requirements by applying SE principles. 2. Reduce the cost of IT operations and PVM cycles. 3. Improve the current PVM methodologies to prevent networked computing systems from becoming the targets of security vulnerability attacks. 4. Embed a Maintenance Optimization Tool (MOT) in the proposed framework. The MOT allows IT managers to make the most practicable choice of methods for deploying and installing released patches and vulnerability remediation. In recent years, there has been a variety of frameworks for security practices in every networked computing system to protect computer workstations from becoming compromised or vulnerable to security attacks, which can expose important information and critical data. I have developed a new mechanism for implementing PVM for maximizing security-vulnerability maintenance, protecting OS and software packages, and minimizing SCPMP cost. To increase computing system security in any diverse environment, particularly in academia, one must apply SCPMP. I propose an optimal maintenance policy that will allow ITDS to measure and estimate the variation of PVM cycles based on their department's requirements. My results demonstrate that MOT optimizes the process of implementing SCPMP in academic workstations.

Heterogeneous Distributed Computing for Computational Aerosciences

NASA Technical Reports Server (NTRS)

Sunderam, Vaidy S.

1998-01-01

The research supported under this award focuses on heterogeneous distributed computing for high-performance applications, with particular emphasis on computational aerosciences. The overall goal of this project was to and investigate issues in, and develop solutions to, efficient execution of computational aeroscience codes in heterogeneous concurrent computing environments. In particular, we worked in the context of the PVM[1] system and, subsequent to detailed conversion efforts and performance benchmarking, devising novel techniques to increase the efficacy of heterogeneous networked environments for computational aerosciences. Our work has been based upon the NAS Parallel Benchmark suite, but has also recently expanded in scope to include the NAS I/O benchmarks as specified in the NHT-1 document. In this report we summarize our research accomplishments under the auspices of the grant.

Performance Evaluation of Communication Software Systems for Distributed Computing

NASA Technical Reports Server (NTRS)

Fatoohi, Rod

1996-01-01

In recent years there has been an increasing interest in object-oriented distributed computing since it is better quipped to deal with complex systems while providing extensibility, maintainability, and reusability. At the same time, several new high-speed network technologies have emerged for local and wide area networks. However, the performance of networking software is not improving as fast as the networking hardware and the workstation microprocessors. This paper gives an overview and evaluates the performance of the Common Object Request Broker Architecture (CORBA) standard in a distributed computing environment at NASA Ames Research Center. The environment consists of two testbeds of SGI workstations connected by four networks: Ethernet, FDDI, HiPPI, and ATM. The performance results for three communication software systems are presented, analyzed and compared. These systems are: BSD socket programming interface, IONA's Orbix, an implementation of the CORBA specification, and the PVM message passing library. The results show that high-level communication interfaces, such as CORBA and PVM, can achieve reasonable performance under certain conditions.

Performance Evaluation in Network-Based Parallel Computing

NASA Technical Reports Server (NTRS)

Dezhgosha, Kamyar

1996-01-01

Network-based parallel computing is emerging as a cost-effective alternative for solving many problems which require use of supercomputers or massively parallel computers. The primary objective of this project has been to conduct experimental research on performance evaluation for clustered parallel computing. First, a testbed was established by augmenting our existing SUNSPARCs' network with PVM (Parallel Virtual Machine) which is a software system for linking clusters of machines. Second, a set of three basic applications were selected. The applications consist of a parallel search, a parallel sort, a parallel matrix multiplication. These application programs were implemented in C programming language under PVM. Third, we conducted performance evaluation under various configurations and problem sizes. Alternative parallel computing models and workload allocations for application programs were explored. The performance metric was limited to elapsed time or response time which in the context of parallel computing can be expressed in terms of speedup. The results reveal that the overhead of communication latency between processes in many cases is the restricting factor to performance. That is, coarse-grain parallelism which requires less frequent communication between processes will result in higher performance in network-based computing. Finally, we are in the final stages of installing an Asynchronous Transfer Mode (ATM) switch and four ATM interfaces (each 155 Mbps) which will allow us to extend our study to newer applications, performance metrics, and configurations.

Generalization of soft phonon modes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rudin, Sven P.

Soft phonon modes describe a collective movement of atoms that transform a higher-symmetry crystal structure into a lower-symmetry crystal structure. Such structural transformations occur at finite temperatures, where the phonons (i.e., the low-temperature vibrational modes) and the static perfect crystal structures provide an incomplete picture of the dynamics. In this paper, principal vibrational modes (PVMs) are introduced as descriptors of the dynamics of a material system withmore » $N$ atoms. The PVMs represent the independent collective movements of the atoms at a given temperature. Molecular dynamics (MD) simulations, here in the form of quantum MD using density functional theory calculations, provide both the data describing the atomic motion and the data used to construct the PVMs. The leading mode, $${\\mathrm{PVM}}_{0}$$, represents the $3N$-dimensional direction in which the system moves with greatest amplitude. For structural phase transitions, $${\\mathrm{PVM}}_{0}$$ serves as a generalization of soft phonon modes. At low temperatures, $${\\mathrm{PVM}}_{0}$$ reproduces the soft phonon mode in systems where one phonon dominates the phase transformation. In general, multiple phonon modes combine to describe a transformation, in which case $${\\mathrm{PVM}}_{0}$$ culls these phonon modes. Moreover, while soft phonon modes arise in the higher-symmetry crystal structure, $${\\mathrm{PVM}}_{0}$$ can be equally well calculated on either side of the structural phase transition. Finally, two applications demonstrate these properties: first, transitions into and out of bcc titanium, and, second, the two crystal structures proposed for the $${\\beta}$$ phase of uranium, the higher-symmetry structure of which stabilizes with temperature.« less

Generalization of soft phonon modes

DOE PAGES

Rudin, Sven P.

2018-04-27

Soft phonon modes describe a collective movement of atoms that transform a higher-symmetry crystal structure into a lower-symmetry crystal structure. Such structural transformations occur at finite temperatures, where the phonons (i.e., the low-temperature vibrational modes) and the static perfect crystal structures provide an incomplete picture of the dynamics. In this paper, principal vibrational modes (PVMs) are introduced as descriptors of the dynamics of a material system withmore » $N$ atoms. The PVMs represent the independent collective movements of the atoms at a given temperature. Molecular dynamics (MD) simulations, here in the form of quantum MD using density functional theory calculations, provide both the data describing the atomic motion and the data used to construct the PVMs. The leading mode, $${\\mathrm{PVM}}_{0}$$, represents the $3N$-dimensional direction in which the system moves with greatest amplitude. For structural phase transitions, $${\\mathrm{PVM}}_{0}$$ serves as a generalization of soft phonon modes. At low temperatures, $${\\mathrm{PVM}}_{0}$$ reproduces the soft phonon mode in systems where one phonon dominates the phase transformation. In general, multiple phonon modes combine to describe a transformation, in which case $${\\mathrm{PVM}}_{0}$$ culls these phonon modes. Moreover, while soft phonon modes arise in the higher-symmetry crystal structure, $${\\mathrm{PVM}}_{0}$$ can be equally well calculated on either side of the structural phase transition. Finally, two applications demonstrate these properties: first, transitions into and out of bcc titanium, and, second, the two crystal structures proposed for the $${\\beta}$$ phase of uranium, the higher-symmetry structure of which stabilizes with temperature.« less

A Systems Engineering Framework for Implementing a Security and Critical Patch Management Process in Diverse Environments (Academic Departments' Workstations)

ERIC Educational Resources Information Center

Mohammadi, Hadi

2014-01-01

Use of the Patch Vulnerability Management (PVM) process should be seriously considered for any networked computing system. The PVM process prevents the operating system (OS) and software applications from being attacked due to security vulnerabilities, which lead to system failures and critical data leakage. The purpose of this research is to…

Modeling and analysis of solar distributed generation

NASA Astrophysics Data System (ADS)

Ortiz Rivera, Eduardo Ivan

Recent changes in the global economy are creating a big impact in our daily life. The price of oil is increasing and the number of reserves are less every day. Also, dramatic demographic changes are impacting the viability of the electric infrastructure and ultimately the economic future of the industry. These are some of the reasons that many countries are looking for alternative energy to produce electric energy. The most common form of green energy in our daily life is solar energy. To convert solar energy into electrical energy is required solar panels, dc-dc converters, power control, sensors, and inverters. In this work, a photovoltaic module, PVM, model using the electrical characteristics provided by the manufacturer data sheet is presented for power system applications. Experimental results from testing are showed, verifying the proposed PVM model. Also in this work, three maximum power point tracker, MPPT, algorithms would be presented to obtain the maximum power from a PVM. The first MPPT algorithm is a method based on the Rolle's and Lagrange's Theorems and can provide at least an approximate answer to a family of transcendental functions that cannot be solved using differential calculus. The second MPPT algorithm is based on the approximation of the proposed PVM model using fractional polynomials where the shape, boundary conditions and performance of the proposed PVM model are satisfied. The third MPPT algorithm is based in the determination of the optimal duty cycle for a dc-dc converter and the previous knowledge of the load or load matching conditions. Also, four algorithms to calculate the effective irradiance level and temperature over a photovoltaic module are presented in this work. The main reasons to develop these algorithms are for monitoring climate conditions, the elimination of temperature and solar irradiance sensors, reductions in cost for a photovoltaic inverter system, and development of new algorithms to be integrated with maximum power point tracking algorithms. Finally, several PV power applications will be presented like circuit analysis for a load connected to two different PV arrays, speed control for a do motor connected to a PVM, and a novel single phase photovoltaic inverter system using the Z-source converter.

Kinetic and kinematic evaluation of compensatory movements of the head, pelvis and thoracolumbar spine associated with asymmetric weight bearing of the pelvic limbs in trotting dogs.

PubMed

Hicks, D A; Millis, D L

2014-01-01

To determine ground reaction forces, head and pelvis vertical motion (HVM and PVM, respectively), and thoraco-lumbar lateral angular motion (LAM) of the spine using kinematic gait analysis in dogs with mild asymmetric weight-bearing of the pelvic limbs while trotting. Twenty-seven hound-type dogs were fitted with reflective markers placed on the sagittal crest of the skull, the ischiatic tuberosity, and thoracolumbar spine of dogs to track motion while trotting. Kinetic and kinematic data were used to characterize asymmetry between the left and right pelvic limbs, and to describe HVM, PVM and thoraco-lumbar LAM. Maximum and minimum position and total motion values were determined for each measured variable. Dogs with asymmetric weight bearing of the pelvic limbs had greater PVM on the side with a greater peak vertical force (PVF), and greater thoraco-lumbar LAM toward the side with a lower PVF while trotting. No differences in mean HVM were detected, and there were no significant correlations between the magnitude of HVM, PVM and thoraco-lumbar LAM and the degree of asymmetric weight bearing. Dogs with subtle asymmetric weight bearing of a pelvic limb had patterns of body motion that may be useful in identifying subtle lameness in dogs; greater PVM on the side with greater weight bearing and greater thoraco-lumbar LAM toward the side with less weight bearing while trotting. Description of these compensatory movements is valuable when evaluating dogs with subtle weight bearing asymmetry in the pelvic limbs and may improve the sensitivity of lameness detection during subjective clinical lameness examination.

Higher operation temperature quadrant photon detectors of 2-11 μm wavelength radiation with large photosensitive areas

NASA Astrophysics Data System (ADS)

Pawluczyk, J.; Sosna, A.; Wojnowski, D.; Koźniewski, A.; Romanis, M.; Gawron, W.; Piotrowski, J.

2017-10-01

We report on the quadrant photon HgCdTe detectors optimized for 2-11 μm wavelength spectral range and Peltier or no cooling, and photosensitive area of a quad-cell of 1×1 to 4×4 mm. The devices are fabricated as photoconductors or multiple photovoltaic cells connected in series (PVM). The former are characterized by a relatively uniform photosensitive area. The PVM photovoltaic cells are distributed along the wafer surface, comprising a periodical stripe structure with a period of 20 μm. Within each period, there is an insensitive gap/trench < 9 μm wide between stripe mesas. The resulting spatial quantization error prevents positioning of the beam spot of size close to the period, but becomes negligible for the optimal spot size comparable to a quadrant-cell area. The photoconductors produce 1/f noise with about 10 kHz knee frequency, due to bias necessary for their operation. The PVM photodiodes are typically operated at 0 V bias, so they generate no 1/f noise and operation from DC is enabled. At 230 K, upper corner frequency of 16 to 100 MHz is obtained for photoconductor and 60 to 80 MHz for PVM, normalized detectivity D* 6×107 cm×Hz1/2/W to >1.4×108 cm×Hz1/2/W for photoconductor and >1.7×108 cm·Hz1/2/W for PVM, allowing for position control of the radiation beam with submicron accuracy at 16 MHz, 10.6 μm wavelength of pulsed radiation spot of 0.8 mm dia at the close-to-maximal input radiation power density in a range of detector linear operation.

Characterization of the passive and active material parameters of the pubovisceralis muscle using an inverse numerical method.

PubMed

Silva, M E T; Parente, M P L; Brandão, S; Mascarenhas, T; Natal Jorge, R M

2018-04-11

The mechanical characteristics of the female pelvic floor are relevant to understand pelvic floor dysfunctions (PFD), and how they are related with changes in their biomechanical behavior. Urinary incontinence (UI) and pelvic organ prolapse (POP) are the most common pathologies, which can be associated with changes in the mechanical properties of the supportive structures in the female pelvic cavity. PFD have been studied through different methods, from experimental tensile tests using tissues from fresh female cadavers or tissues collected at the time of a transvaginal hysterectomy procedure, or by applying imaging techniques. In this work, an inverse finite element analysis (FEA) was applied to understand the passive and active behavior of the pubovisceralis muscle (PVM) during Valsalva maneuver and muscle active contraction, respectively. Individual numerical models of women without pathology, with stress UI (SUI) and POP were built based on magnetic resonance images, including the PVM and surrounding structures. The passive and active material parameters obtained for a transversely isotropic hyperelastic constitutive model were estimated for the three groups. The values for the material constants were significantly higher for the women with POP when compared with the other two groups. The PVM of women with POP showed the highest stiffness. Additionally, the influence of these parameters was analyzed by evaluating their stress-strain, and force-displacements responses. The force produced by the PVM in women with POP was 47% and 82% higher when compared to women without pathology and with SUI, respectively. The inverse FEA allowed estimating the material parameters of the PVM using input information acquired non-invasively. Copyright © 2018 Elsevier Ltd. All rights reserved.

Service learning: Priority 4 Paws mobile surgical service for shelter animals.

PubMed

Freeman, Lynetta J; Ferguson, Nancy; Litster, Annette; Arighi, Mimi

2013-01-01

The increasing attention given to competencies needed to enter the workforce has revealed a need for veterinary students to gain more experience in performing small-animal elective surgery before graduation. In addition, guidelines for standards of care for shelter animals recommend that all dogs and cats should be spayed or neutered before adoption. Teaching surgical skills while serving the needs of local animal shelters represents an ideal service-learning opportunity. Following a pilot study and the benchmarking of other programs, an elective course in shelter medicine and surgery was created at Purdue University College of Veterinary Medicine (PVM) to allow senior DVM students an opportunity to spend 2 weeks on a mobile surgery unit (Priority 4 Paws) and 1 week at an animal shelter. With financial assistance from sponsors and donors, PVM purchased and equipped a mobile surgery unit, hired a full-time veterinarian and a registered veterinary technician, and established relationships with 12 animal shelters. From July 30, 2012, to March 22, 2013, 1,941 spays and neuters were performed with excellent postsurgical outcomes while training 33 veterinary students on rotation and 26 veterinary technician students. The program was well accepted by both students and the shelters being served. The Priority 4 Paws program is an example of an integrated, community-based service-learning opportunity that not only helps to improve the surgical skills of veterinary students but also helps to meet an identified community need.

Improved approach to quantitative cardiac volumetrics using automatic thresholding and manual trimming: a cardiovascular MRI study.

PubMed

Rayarao, Geetha; Biederman, Robert W W; Williams, Ronald B; Yamrozik, June A; Lombardi, Richard; Doyle, Mark

2018-01-01

To establish the clinical validity and accuracy of automatic thresholding and manual trimming (ATMT) by comparing the method with the conventional contouring method for in vivo cardiac volume measurements. CMR was performed on 40 subjects (30 patients and 10 controls) using steady-state free precession cine sequences with slices oriented in the short-axis and acquired contiguously from base to apex. Left ventricular (LV) volumes, end-diastolic volume, end-systolic volume, and stroke volume (SV) were obtained with ATMT and with the conventional contouring method. Additionally, SV was measured independently using CMR phase velocity mapping (PVM) of the aorta for validation. Three methods of calculating SV were compared by applying Bland-Altman analysis. The Bland-Altman standard deviation of variation (SD) and offset bias for LV SV for the three sets of data were: ATMT-PVM (7.65, [Formula: see text]), ATMT-contours (7.85, [Formula: see text]), and contour-PVM (11.01, 4.97), respectively. Equating the observed range to the error contribution of each approach, the error magnitude of ATMT:PVM:contours was in the ratio 1:2.4:2.5. Use of ATMT for measuring ventricular volumes accommodates trabeculae and papillary structures more intuitively than contemporary contouring methods. This results in lower variation when analyzing cardiac structure and function and consequently improved accuracy in assessing chamber volumes.

Start-up capabilities of photovoltaic module for the International Space Station

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hajela, G.; Hague, L.

1997-12-31

The International Space Station (ISS) uses four photovoltaic modules (PVMs) to supply electric power for the US On-Orbit Segment (USOS). The ISS is assembled on orbit over a period of about 5 years and over 40 stages. PVMs are launched and integrated with the ISS at different times during the ISS assembly. During early stages, the electric power is provided by the integrated truss segment (ITS) P6; subsequently, ITS P4, S4, and S6 are launched. PVMs are launched into space in the National Space Transportation System (NSTS) cargo bay. Each PVM consists of two independent power channels. The NSTS docksmore » with the ISS, the PVM is removed from the cargo bay and installed on the ISS. At this stage the PVM is in stowed configuration and its batteries are in fully discharged state. The start-up consists of initialization and checkout of all hardware, deployment of SAW and photovoltaic radiator (PVR), thermal conditioning batteries, and charging batteries; not necessarily in the same order for all PVMs. PVMs are designed to be capable of on-orbit start-up, within a specified time period, when external power is applied to a specified electrical interface. This paper describes the essential steps required for PVM start-up and how these operations are performed for various PVMs. The integrated operations scenarios (IOS) prepared by the NASA, Johnson Space Center, details specific procedures and timelines for start-up of each PVM. The paper describes how dormant batteries are brought to their normal operating temperature range and then charged to 100% state of charge (SOC). Total time required to complete start-up is computed and compared to the IOS timelines. External power required during start-up is computed and compared to the requirements and/or available power on ISS. Also described is how these start-up procedures can be adopted for restart of PVMs when required.« less

THE MODIFYING EFFECTS OF CERTAIN SUBSTANCES OF BACTERIAL ORIGIN ON THE COURSE OF INFECTION WITH PNEUMONIA VIRUS OF MICE (PVM)

PubMed Central

Horsfall, Frank L.; McCarty, Maclyn

1947-01-01

Evidence is presented which indicates that certain polysaccharide preparations derived from various bacterial species, as well as similar materials not of bacterial origin, are capable of lessening the severity of infection with pneumonia virus of mice (PVM) and inhibiting multiplication of the virus in mouse lungs infected with this agent. It seems probable that modification with respect to the virus is mediated by a substance which may be polysaccharide in nature. PMID:19871640

Reflections on the ethics of participatory visual methods to engage communities in global health research

PubMed Central

Black, Gillian F.; Davies, Alun; Iskander, Dalia; Chambers, Mary

2018-01-01

ABSTRACT There is a growing body of literature describing conceptual frameworks for working with participatory visual methods (PVM). Through a global health lens, this paper examines some key themes within these frameworks. We reflect on our experiences of working with with an array of PVM to engage community members in Vietnam, Kenya, the Philippines and South Africa in biomedical research and public health. The participants that we have engaged in these processes live in under-resourced areas with high prevalence of communicable and non-communicable diseases. Our paper describes some of the challenges that we have encountered while using PVM to foster knowledge exchange, build relationships and facilitate change among individuals and families, community members, health workers, biomedical scientists and researchers. We consider multiple ethical situations that have arisen through our work and discuss the ways in which we have navigated and negotiated them. We offer our reflections and learning from facilitating these processes and in doing so we add novel contributions to ethical framework concepts. PMID:29434532

A distributed monitoring system for photovoltaic arrays based on a two-level wireless sensor network

NASA Astrophysics Data System (ADS)

Su, F. P.; Chen, Z. C.; Zhou, H. F.; Wu, L. J.; Lin, P. J.; Cheng, S. Y.; Li, Y. F.

2017-11-01

In this paper, a distributed on-line monitoring system based on a two-level wireless sensor network (WSN) is proposed for real time status monitoring of photovoltaic (PV) arrays to support the fine management and maintenance of PV power plants. The system includes the sensing nodes installed on PV modules (PVM), sensing and routing nodes installed on combiner boxes of PV sub-arrays (PVA), a sink node and a data management centre (DMC) running on a host computer. The first level WSN is implemented by the low-cost wireless transceiver nRF24L01, and it is used to achieve single hop communication between the PVM nodes and their corresponding PVA nodes. The second level WSN is realized by the CC2530 based ZigBee network for multi-hop communication among PVA nodes and the sink node. The PVM nodes are used to monitor the PVM working voltage and backplane temperature, and they send the acquired data to their PVA node via the nRF24L01 based first level WSN. The PVA nodes are used to monitor the array voltage, PV string current and environment irradiance, and they send the acquired and received data to the DMC via the ZigBee based second level WSN. The DMC is designed using the MATLAB GUIDE and MySQL database. Laboratory experiment results show that the system can effectively acquire, display, store and manage the operating and environment parameters of PVA in real time.

The " Swarm of Ants vs. Herd of Elephants" Debated Revisited: Performance Measurements of PVM-Overflow Across a Wide Spectrum of Architectures

NASA Technical Reports Server (NTRS)

Yan, Jerry C.; Jespersen, Dennis; Buning, Peter; Bailey, David (Technical Monitor)

1996-01-01

The Gorden Bell Prizes given out at Supercomputing every year includes at least two catergories: performance (highest GFLOP count) and price-performance (GFLOP/million $$) for real applications. In the past five years, the winners of the price-performance categories all came from networks of work-stations. This reflects three important facts: 1. supercomputers are still too expensive for the masses; 2. achieving high performance for real applications takes real work; and, most importantly; 3. it is possible to obtain acceptable performance for certain real applications on network of work stations. With the continued advance of network technology as well as increased performance of "desktop" workstation, the "Swarm of Ants vs. Herd of Elephants" debate, which began with vector multiprocessors (VPPs) against SIMD type multiprocessors (e.g. CM2), is now recast as VPPs against Symetric Multiprocessors (SMPs, e.g. SGI PowerChallenge). This paper reports on performance studies we performed solving a large scale (2-million grid pt.s) CFD problem involving a Boeing 747 based on a parallel version of OVERFLOW that utilizes message passing on PVM. A performance monitoring tool developed under NASA HPCC, called AIMS, was used to instrument and analyze the the performance data thus obtained. We plan to compare its performance data obtained across a wide spectrum of architectures including: the Cray C90, IBM/SP2, SGI/Power Challenge Cluster, to a group of workstations connected over a simple network. The metrics of comparison includes speed-up, price-performance, throughput, and turn-around time. We also plan to present a plan of attack for various issues that will make the execution of Grand Challenge Applications across the Global Information Infrastructure a reality.

Immunobiotic Lactobacillus administered post-exposure averts the lethal sequelae of respiratory virus infection.

PubMed

Percopo, Caroline M; Rice, Tyler A; Brenner, Todd A; Dyer, Kimberly D; Luo, Janice L; Kanakabandi, Kishore; Sturdevant, Daniel E; Porcella, Stephen F; Domachowske, Joseph B; Keicher, Jesse D; Rosenberg, Helene F

2015-09-01

We reported previously that priming of the respiratory tract with immunobiotic Lactobacillus prior to virus challenge protects mice against subsequent lethal infection with pneumonia virus of mice (PVM). We present here the results of gene microarray which document differential expression of proinflammatory mediators in response to PVM infection alone and those suppressed in response to Lactobacillus plantarum. We also demonstrate for the first time that intranasal inoculation with live or heat-inactivated L. plantarum or Lactobacillus reuteri promotes full survival from PVM infection when administered within 24h after virus challenge. Survival in response to L. plantarum administered after virus challenge is associated with suppression of proinflammatory cytokines, limited virus recovery, and diminished neutrophil recruitment to lung tissue and airways. Utilizing this post-virus challenge protocol, we found that protective responses elicited by L. plantarum at the respiratory tract were distinct from those at the gastrointestinal mucosa, as mice devoid of the anti-inflammatory cytokine, interleukin (IL)-10, exhibit survival and inflammatory responses that are indistinguishable from those of their wild-type counterparts. Finally, although L. plantarum interacts specifically with pattern recognition receptors TLR2 and NOD2, the respective gene-deleted mice were fully protected against lethal PVM infection by L. plantarum, as are mice devoid of type I interferon receptors. Taken together, L. plantarum is a versatile and flexible agent that is capable of averting the lethal sequelae of severe respiratory infection both prior to and post-virus challenge via complex and potentially redundant mechanisms. Published by Elsevier B.V.

Torins are potent antimalarials that block replenishment of Plasmodium liver stage parasitophorous vacuole membrane proteins

PubMed Central

Hanson, Kirsten K.; Ressurreição, Ana S.; Buchholz, Kathrin; Prudêncio, Miguel; Herman-Ornelas, Jonathan D.; Rebelo, Maria; Beatty, Wandy L.; Wirth, Dyann F.; Hänscheid, Thomas; Moreira, Rui; Marti, Matthias; Mota, Maria M.

2013-01-01

Residence within a customized vacuole is a highly successful strategy used by diverse intracellular microorganisms. The parasitophorous vacuole membrane (PVM) is the critical interface between Plasmodium parasites and their possibly hostile, yet ultimately sustaining, host cell environment. We show that torins, developed as ATP-competitive mammalian target of rapamycin (mTOR) kinase inhibitors, are fast-acting antiplasmodial compounds that unexpectedly target the parasite directly, blocking the dynamic trafficking of the Plasmodium proteins exported protein 1 (EXP1) and upregulated in sporozoites 4 (UIS4) to the liver stage PVM and leading to efficient parasite elimination by the hepatocyte. Torin2 has single-digit, or lower, nanomolar potency in both liver and blood stages of infection in vitro and is likewise effective against both stages in vivo, with a single oral dose sufficient to clear liver stage infection. Parasite elimination and perturbed trafficking of liver stage PVM-resident proteins are both specific aspects of torin-mediated Plasmodium liver stage inhibition, indicating that torins have a distinct mode of action compared with currently used antimalarials. PMID:23836641

High-energy physics software parallelization using database techniques

NASA Astrophysics Data System (ADS)

Argante, E.; van der Stok, P. D. V.; Willers, I.

1997-02-01

A programming model for software parallelization, called CoCa, is introduced that copes with problems caused by typical features of high-energy physics software. By basing CoCa on the database transaction paradimg, the complexity induced by the parallelization is for a large part transparent to the programmer, resulting in a higher level of abstraction than the native message passing software. CoCa is implemented on a Meiko CS-2 and on a SUN SPARCcenter 2000 parallel computer. On the CS-2, the performance is comparable with the performance of native PVM and MPI.

Scalability and Portability of Two Parallel Implementations of ADI

NASA Technical Reports Server (NTRS)

Phung, Thanh; VanderWijngaart, Rob F.

1994-01-01

Two domain decompositions for the implementation of the NAS Scalar Penta-diagonal Parallel Benchmark on MIMD systems are investigated, namely transposition and multi-partitioning. Hardware platforms considered are the Intel iPSC/860 and Paragon XP/S-15, and clusters of SGI workstations on ethernet, communicating through PVM. It is found that the multi-partitioning strategy offers the kind of coarse granularity that allows scaling up to hundreds of processors on a massively parallel machine. Moreover, efficiency is retained when the code is ported verbatim (save message passing syntax) to a PVM environment on a modest size cluster of workstations.

Reconditioning of Batteries on the International Space Station

NASA Technical Reports Server (NTRS)

Hajela, Gyan; Cohen, Fred; Dalton, Penni

2004-01-01

Primary source of electric power for the International Space Station (ISS) is the photovoltaic module (PVM). At assembly complete stage, the ISS will be served by 4 PVMs. Each PVM contains two independent power channels such that one failure will result in loss of only one power channel. During early stages of assembly, the ISS is served by only one PVM designated as P6. Solar arrays are used to convert solar flux into electrical power. Nickel hydrogen batteries are used to store electrical power for use during periods when the solar input is not adequate to support channel loads. Batteries are operated per established procedures that ensure that they are maintained within specified temperature limits, charge current is controlled to conform to a specified charge profile, and battery voltages are maintained within specified limits. Both power channels on the PVM P6 have been operating flawlessly since December 2000 with 100 percent power availability. All components, including batteries, are monitored regularly to ensure that they are operating within specified limits and to trend their wear out and age effects. The paper briefly describes the battery trend data. Batteries have started to show some effects of aging and a battery reconditioning procedure is being evaluated at this time. Reconditioning is expected to reduce cell voltage divergence and provide data that can be used to update the state of charge (SOC) computation in the software to account for battery age. During reconditioning, each battery, one at a time, will be discharged per a specified procedure and then returned to a full state of charge. The paper describes the reconditioning procedure and the expected benefits. The reconditioning procedures have been thoroughly coordinated by all affected technical teams and approved by all required boards. The reconditioning is tentatively scheduled for September 2004.

Lactobacillus priming of the respiratory tract: Heterologous immunity and protection against lethal pneumovirus infection.

PubMed

Garcia-Crespo, Katia E; Chan, Calvin C; Gabryszewski, Stanislaw J; Percopo, Caroline M; Rigaux, Peter; Dyer, Kimberly D; Domachowske, Joseph B; Rosenberg, Helene F

2013-03-01

We showed previously that wild-type mice primed via intranasal inoculation with live or heat-inactivated Lactobacillus species were fully (100%) protected against the lethal sequelae of infection with the virulent pathogen, pneumonia virus of mice (PVM), a response that is associated with diminished expression of proinflammatory cytokines and diminished virus recovery. We show here that 40% of the mice primed with live Lactobacillus survived when PVM challenge was delayed for 5months. This robust and sustained resistance to PVM infection resulting from prior interaction with an otherwise unrelated microbe is a profound example of heterologous immunity. We undertook the present study in order to understand the nature and unique features of this response. We found that intranasal inoculation with L. reuteri elicited rapid, transient neutrophil recruitment in association with proinflammatory mediators (CXCL1, CCL3, CCL2, CXCL10, TNF-alpha and IL-17A) but not Th1 cytokines. IFNγ does not contribute to survival promoted by Lactobacillus-priming. Live L. reuteri detected in lung tissue underwent rapid clearance, and was undetectable at 24h after inoculation. In contrast, L. reuteri peptidoglycan (PGN) and L. reuteri genomic DNA (gDNA) were detected at 24 and 48h after inoculation, respectively. In contrast to live bacteria, intranasal inoculation with isolated L. reuteri gDNA elicited no neutrophil recruitment, had minimal impact on virus recovery and virus-associated production of CCL3, and provided no protection against the negative sequelae of virus infection. Isolated PGN elicited neutrophil recruitment and proinflammatory cytokines but did not promote sustained survival in response to subsequent PVM infection. Overall, further evaluation of the responses leading to Lactobacillus-mediated heterologous immunity may provide insight into novel antiviral preventive modalities. Published by Elsevier B.V.

Lactobacillus priming of the respiratory tract: heterologous immunity and protection against lethal pneumovirus infection

PubMed Central

Garcia-Crespo, Katia E.; Chan, Calvin C.; Gabryszewski, Stanislaw J.; Percopo, Caroline M.; Rigaux, Peter; Dyer, Kimberly D.; Domachowske, Joseph B.; Rosenberg, Helene F.

2013-01-01

We showed previously that wild-type mice primed via intranasal inoculation with live or heat-inactivated Lactobacillus species were fully (100%) protected against the lethal sequelae of infection with the virulent pathogen, pneumonia virus of mice (PVM), a response that is associated with diminished expression of proinflammatory cytokines and diminished virus recovery. We show here that 40% of the mice primed with live Lactobacillus survived when PVM challenge was delayed for 5 months. This robust and sustained resistance to PVM infection resulting from prior interaction with an otherwise unrelated microbe is a profound example of heterologous immunity. We undertook the present study in order to understand the nature and unique features of this response. We found that intranasal inoculation with L. reuteri elicited rapid, transient neutrophil recruitment in association with proinflammatory mediators (CXCL1, CCL3, CCL2, CXCL10, TNF-alpha and IL-17A) but not Th1 cytokines. IFNγ does not contribute to survival promoted by Lactobacillus-priming. Live L. reuteri detected in lung tissue underwent rapid clearance, and was undetectable at 24 hrs after inoculation. In contrast, L. reuteri peptidoglycan (PGN) and L. reuteri genomic DNA (gDNA) were detected at 24 and 48 hours after inoculation, respectively. In contrast to live bacteria, intranasal inoculation with isolated L. reuteri gDNA elicited no neutrophil recruitment, had minimal impact on virus recovery and virus-associated production of CCL3, and provided no protection against the negative sequelae of virus infection. Isolated PGN elicited neutrophil recruitment and proinflammatory cytokines but did not promote sustained survival in response to subsequent PVM infection. Overall, further evaluation of the responses leading to Lactobacillus-mediated heterologous immunity may provide insight into novel antiviral preventive modalities. PMID:23274789

Effect of a triclosan/PVM/MA copolymer/fluoride dentifrice on volatile sulfur compounds in vitro.

PubMed

Pilch, S; Williams, M I; Cummins, D

2005-01-01

The objective of the investigation was to document the in vitro efficacy of a triclosan/PVM/MA copolymer/fluoride (TCF) dentifrice against the formation of volatile sulfur compounds (VSC) as well as the growth of H2S-producing bacteria. Clinical studies using organoleptic judges, gas chromatography, or a portable sulfide monitor have generally been employed in the assessment of treatments for the control of oral malodor. However, these studies are not appropriate for screening purposes because of the expense and time required. An in vitro method was developed for the purpose of screening new compounds, agents or formulations for their ability to control VSC formation and for determining bio-equivalence of efficacy when implementing changes in existing formulations. The method combines basic microbiological methods, dynamic flow cell techniques and head space analysis. The in vitro VSC method was validated by comparing the efficacy of two dentifrices containing TCF with a control fluoride dentifrice as the TCF products have been clinically proven to control oral malodor. In the validation studies, the TCF-containing dentifrices were significantly better (P < 0.05) than the control dentifrice in inhibiting VSC formation and reducing H(2)S-producing bacteria. For example, when compared with baseline, the TCF dentifrices reduced VSC formation between 42 and 49% compared with the control dentifrice which reduced VSC formation 3%. There was no significant difference (P > 0.05) between the two TCF dentifrice formulations. Using an in vitro breath VSC model, it has been demonstrated that two variants of a dentifrice containing triclosan, PVM/MA copolymer and fluoride have efficacy that is significantly better than a control fluoridated dentifrice and that there is no significant difference between the triclosan/PVM/MA copolymer/fluoride dentifrice variants.

Heterogeneous voter models

NASA Astrophysics Data System (ADS)

Masuda, Naoki; Gibert, N.; Redner, S.

2010-07-01

We introduce the heterogeneous voter model (HVM), in which each agent has its own intrinsic rate to change state, reflective of the heterogeneity of real people, and the partisan voter model (PVM), in which each agent has an innate and fixed preference for one of two possible opinion states. For the HVM, the time until consensus is reached is much longer than in the classic voter model. For the PVM in the mean-field limit, a population evolves to a preference-based state, where each agent tends to be aligned with its internal preference. For finite populations, discrete fluctuations ultimately lead to consensus being reached in a time that scales exponentially with population size.

Monitoring of antisolvent crystallization of sodium scutellarein by combined FBRM-PVM-NIR.

PubMed

Liu, Xuesong; Sun, Di; Wang, Feng; Wu, Yongjiang; Chen, Yong; Wang, Longhu

2011-06-01

Antisolvent crystallization can be used as an alternative to cooling or evaporation for the separation and purification of solid product in the pharmaceutical industry. To improve the process understanding of antisolvent crystallization, the use of in-line tools is vital. In this study, the process analytical technology (PAT) tools including focused beam reflectance measurement (FBRM), particle video microscope (PVM), and near-infrared spectroscopy (NIRS) were utilized to monitor antisolvent crystallization of sodium scutellarein. FBRM was used to monitor chord count and chord length distribution of sodium scutellarein particles in the crystallizer, and PVM, as an in-line video camera, provided pictures imaging particle shape and dimension. In addition, a quantitative model of PLS was established by in-line NIRS to detect the concentration of sodium scutellarein in the solvent and good calibration statistics were obtained (r(2) = 0.976) with the residual predictive deviation value of 11.3. The discussion over sensitivities, strengths, and weaknesses of the PAT tools may be helpful in selection of suitable PAT techniques. These in-line techniques eliminate the need for sample preparation and offer a time-saving approach to understand and monitor antisolvent crystallization process. Copyright © 2011 Wiley-Liss, Inc.

Fundamental Roles of the Golgi-Associated Toxoplasma Aspartyl Protease, ASP5, at the Host-Parasite Interface

PubMed Central

Hammoudi, Pierre-Mehdi; Jacot, Damien; Mueller, Christina; Di Cristina, Manlio; Dogga, Sunil Kumar; Marq, Jean-Baptiste; Romano, Julia; Tosetti, Nicolò; Dubrot, Juan; Emre, Yalin; Lunghi, Matteo; Coppens, Isabelle; Yamamoto, Masahiro; Sojka, Daniel; Pino, Paco; Soldati-Favre, Dominique

2015-01-01

Toxoplasma gondii possesses sets of dense granule proteins (GRAs) that either assemble at, or cross the parasitophorous vacuole membrane (PVM) and exhibit motifs resembling the HT/PEXEL previously identified in a repertoire of exported Plasmodium proteins. Within Plasmodium spp., cleavage of the HT/PEXEL motif by the endoplasmic reticulum-resident protease Plasmepsin V precedes trafficking to and export across the PVM of proteins involved in pathogenicity and host cell remodelling. Here, we have functionally characterized the T. gondii aspartyl protease 5 (ASP5), a Golgi-resident protease that is phylogenetically related to Plasmepsin V. We show that deletion of ASP5 causes a significant loss in parasite fitness in vitro and an altered virulence in vivo. Furthermore, we reveal that ASP5 is necessary for the cleavage of GRA16, GRA19 and GRA20 at the PEXEL-like motif. In the absence of ASP5, the intravacuolar nanotubular network disappears and several GRAs fail to localize to the PVM, while GRA16 and GRA24, both known to be targeted to the host cell nucleus, are retained within the vacuolar space. Additionally, hypermigration of dendritic cells and bradyzoite cyst wall formation are impaired, critically impacting on parasite dissemination and persistence. Overall, the absence of ASP5 dramatically compromises the parasite’s ability to modulate host signalling pathways and immune responses. PMID:26473595

A clinical investigation of the efficacy of three commercially available dentifrices for controlling established gingivitis and supragingival plaque.

PubMed

Singh, Surrendra; Chaknis, Patricia; DeVizio, William; Petrone, Margaret; Panagakos, Fotinos S; Proskin, Howard M

2010-01-01

To assess the efficacy ofa dentifrice containing 0.3% triclosan/2.0% PVM/MA copolymer/0.243% sodium fluoride for controlling established gingivitis and supragingival plaque relative to that of a dentifrice containing 0.454% stannous fluoride, sodium hexametaphosphate, and zinc lactate, and a dentifrice containing 0.243% sodium fluoride as a negative control. Following a baseline examination for gingivitis and supragingival plaque, qualifying adult male and female subjects from the Piscataway, NJ, USA area were randomized into three dentifrice groups. Subjects were instructed to brush their teeth twice daily (morning and evening) for one minute with their assigned dentifrice and a soft-bristled toothbrush. Examinations for gingivitis and supragingival plaque were repeated after six weeks of product use. One-hundred and seventy-one (171) subjects complied with the protocol and completed the study. Relative to the group using the dentifrice with 0.243% sodium fluoride alone, the 0.3% triclosan/2.0% PVM/MA copolymer/0.243% sodium fluoride group exhibited statistically significant reductions in gingival index and supragingival plaque index scores of 25.3% and 33.0%, respectively, after six weeks of product use. Similarly, relative to the group using the 0.243% sodium fluoride dentifrice, the 0.454% stannous fluoride, sodium hexametaphosphate, and zinc lactate dentifrice group exhibited statistically significant reductions in gingival index and plaque index scores of 8.1% and 14.1% after six weeks of product use. Further, relative to the 0.454% stannous fluoride, sodium hexametaphosphate, and zinc lactate dentifrice group, the 0.3% triclosan/2.0% PVM/MA copolymer/0.243% sodium fluoride dentifrice group exhibited statistically significant reductions in gingival index and plaque index scores of 18.7% and 22%, respectively. The overall results of this double-blind clinical study support the conclusion that a dentifrice containing 0.3% triclosan/2.0% PVM/MA copolymer/0.243% sodium fluoride is efficacious for the control of established gingivitis and supragingival plaque as compared to a regular fluoride dentifrice, and that it provides a greater level of efficacy for the control of gingivitis and supragingival plaque than does a dentifrice containing 0.454% stannous fluoride, sodium hexametaphosphate, and zinc lactate.

Muscarinic excitation of parvalbumin-positive interneurons contributes to the severity of pilocarpine-induced seizures

PubMed Central

Yi, Feng; DeCan, Evan; Stoll, Kurt; Marceau, Eric; Deisseroth, Karl; Lawrence, J. Josh

2014-01-01

SUMMARY Objective A common rodent model in epilepsy research employs the muscarinic acetylcholine receptor (mAChR) agonist pilocarpine, yet the mechanisms underlying the induction of pilocarpine-induced seizures (PISs) remain unclear. Global M1 mAChR (M1R) knockout mice are resistant to PISs, implying that M1R activation disrupts excitation/inhibition balance. Parvalbumin-positive (PV) inhibitory neurons express M1 mAChRs, participate in cholinergically-induced oscillations, and can enter a state of depolarization block (DB) during epileptiform activity. Here, we test the hypothesis that pilocarpine activation of M1Rs expressed on PV cells contributes to PISs. Methods CA1 PV cells in PV-CRE mice were visualized with a floxed YFP or hM3Dq-mCherry adeno-associated virus, or by crossing PV-CRE mice with the RosaYFP reporter line. To eliminate M1Rs from PV cells, we generated PV-M1KO mice by crossing PV-CRE and floxed M1 mice. Action potential (AP) frequency was monitored during application of pilocarpine (200 µM). In behavioral experiments, locomotion and seizure symptoms were recorded in WT or PV-M1KO mice during PISs. Results Pilocarpine significantly increased AP frequency in CA1 PV cells into the gamma range. In the continued presence of pilocarpine, a subset (5/7) of PV cells progressed to DB, which was mimicked by hM3Dq activation of Gq-receptor signaling. Pilocarpine-induced depolarization, AP firing at gamma frequency, and progression to DB were prevented in CA1 PV cells of PV-M1KO mice. Finally, compared to WT mice, PV-M1KO mice were associated with reduced severity of PISs. Significance Pilocarpine can directly depolarize PV+ cells via M1R activation but a subset of these cells progress to DB. Our electrophysiological and behavioral results suggest that this mechanism is active during PISs, contributing to a collapse of PV-mediated GABAergic inhibition, dysregulation of excitation/inhibition balance, and increased susceptibility to PISs. PMID:25495999

Preparation and characterization of mucoadhesive nanoparticles of poly (methyl vinyl ether-co-maleic anhydride) containing glycyrrhizic acid intended for vaginal administration.

PubMed

Aguilar-Rosas, Irene; Alcalá-Alcalá, Sergio; Llera-Rojas, Viridiana; Ganem-Rondero, Adriana

2015-01-01

Traditional vaginal preparations reside in the vaginal cavity for relatively a short period of time, requiring multiple doses in order to attain the desired therapeutic effect. Therefore, mucoadhesive systems appear to be appropriate to prolong the residence time in the vaginal cavity. In the current study, mucoadhesive nanoparticles based on poly(methyl vinyl ether-co-maleic anhydride) (PVM/MA) intended for vaginal delivery of glycyrrhizic acid (GA) (a drug with well-known antiviral properties) were prepared and characterized. Nanoparticles were generated by a solvent displacement method. Incorporation of GA was performed during nanoprecipitation, followed by adsorption of drug once nanoparticles were formed. The prepared nanoparticles were characterized in terms of size, Z-potential, morphology, drug loading, interaction of GA with PVM/MA (by differential scanning calorimetry) and the in vitro interaction of nanoparticles with pig mucin (at two pH values, 3.6 and 5; with and without GA adsorbed). The preparation method led to nanoparticles of a mean diameter of 198.5 ± 24.3 nm, zeta potential of -44.8 ± 2.8 mV and drug loading of 15.07 ± 0.86 µg/mg polymer. The highest mucin interaction resulted at pH 3.6 for nanoparticles without GA adsorbed. The data obtained suggest the promise of using mucoadhesive nanoparticles of PVM/MA for intravaginal delivery of GA.

Non-equilibrium plasma kinetics of reacting CO: an improved state to state approach

NASA Astrophysics Data System (ADS)

Pietanza, L. D.; Colonna, G.; Capitelli, M.

2017-12-01

Non-equilibrium plasma kinetics of reacting CO for conditions typically met in microwave discharges have been developed based on the coupling of excited state kinetics and the Boltzmann equation for the electron energy distribution function (EEDF). Particular attention is given to the insertion in the vibrational kinetics of a complete set of electron molecule resonant processes linking the whole vibrational ladder of the CO molecule, as well as to the role of Boudouard reaction, i.e. the process of forming CO2 by two vibrationally excited CO molecules, in shaping the vibrational distribution of CO and promoting reaction channels assisted by vibrational excitation (pure vibrational mechanisms, PVM). PVM mechanisms can become competitive with electron impact dissociation processes (DEM) in the activation of CO. A case study reproducing the conditions of a microwave discharge has been considered following the coupled kinetics also in the post discharge conditions. Results include the evolution of EEDF in discharge and post discharge conditions highlighting the role of superelastic vibrational and electronic collisions in shaping the EEDF. Moreover, PVM rate coefficients and DEM ones are studied as a function of gas temperature, showing a non-Arrhenius behavior, i.e. the rate coefficients increase with decreasing gas temperature as a result of a vibrational-vibrational (V-V) pumping up mechanism able to form plateaux in the vibrational distribution function. The accuracy of the results is discussed in particular in connection to the present knowledge of the activation energy of the Boudouard process.

Effects of Ramadan Gasting on Postural Balance and Attentional Capacities in Elderly People.

PubMed

Laatar, R; Borji, R; Baccouch, R; Zahaf, F; Rebai, H; Sahli, S

2016-01-01

To evaluate the effects of Ramadan fasting on postural balance and attentional capacities in older adults. the Neurophysiology department of a University Hospital. Fifteen males aged between 65 and 80 years were asked to perform a postural balance protocol and a simple reaction time (SRT) test in four testing phases: one week before Ramadan (BR), during the second (SWR) and the fourth week of Ramadan (FWR) and 3 weeks after Ramadan (AR). Postural balance measurements were recorded in the bipedal stance in four different conditions: firm surface/eyes open (EO), firm surface/eyes closed (EC), foam surface/EO and foam surface/EC using a force platform. Results of the present study demonstrated that center of pressure (CoP) mean velocity (CoPVm), medio-lateral length (CoPLX) and antero-posterior length (CoPLY) were significantly higher during the SWR than BR. Likewise, values of CoPVm and CoPLX increased significantly during the FWR compared to BR. The CoPLX decreased significantly in the FWR compared to the SWR. Values of CoPVm and CoPLX were significantly higher AR in comparison with BR. In addition, SRT values increased significantly during the SWR and the FWR than BR. Ramadan fasting affects postural balance and attentional capacities in the elderly mainly in the SWR and it may, therefore, increase the risk of fall and fall-related injuries. More than three weeks are needed for older adults to recover postural balance impairment due to Ramadan fasting.

Parallel algorithms for modeling flow in permeable media. Annual report, February 15, 1995 - February 14, 1996

DOE Office of Scientific and Technical Information (OSTI.GOV)

G.A. Pope; K. Sephernoori; D.C. McKinney

1996-03-15

This report describes the application of distributed-memory parallel programming techniques to a compositional simulator called UTCHEM. The University of Texas Chemical Flooding reservoir simulator (UTCHEM) is a general-purpose vectorized chemical flooding simulator that models the transport of chemical species in three-dimensional, multiphase flow through permeable media. The parallel version of UTCHEM addresses solving large-scale problems by reducing the amount of time that is required to obtain the solution as well as providing a flexible and portable programming environment. In this work, the original parallel version of UTCHEM was modified and ported to CRAY T3D and CRAY T3E, distributed-memory, multiprocessor computersmore » using CRAY-PVM as the interprocessor communication library. Also, the data communication routines were modified such that the portability of the original code across different computer architectures was mad possible.« less

Prototype Vector Machine for Large Scale Semi-Supervised Learning

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Kai; Kwok, James T.; Parvin, Bahram

2009-04-29

Practicaldataminingrarelyfalls exactlyinto the supervisedlearning scenario. Rather, the growing amount of unlabeled data poses a big challenge to large-scale semi-supervised learning (SSL). We note that the computationalintensivenessofgraph-based SSLarises largely from the manifold or graph regularization, which in turn lead to large models that are dificult to handle. To alleviate this, we proposed the prototype vector machine (PVM), a highlyscalable,graph-based algorithm for large-scale SSL. Our key innovation is the use of"prototypes vectors" for effcient approximation on both the graph-based regularizer and model representation. The choice of prototypes are grounded upon two important criteria: they not only perform effective low-rank approximation of themore » kernel matrix, but also span a model suffering the minimum information loss compared with the complete model. We demonstrate encouraging performance and appealing scaling properties of the PVM on a number of machine learning benchmark data sets.« less

Modeling of spectral signatures of littoral waters

NASA Astrophysics Data System (ADS)

Haltrin, Vladimir I.

1997-12-01

The spectral values of remotely obtained radiance reflectance coefficient (RRC) are compared with the values of RRC computed from inherent optical properties measured during the shipborne experiment near the West Florida coast. The model calculations are based on the algorithm developed at the Naval Research Laboratory at Stennis Space Center and presented here. The algorithm is based on the radiation transfer theory and uses regression relationships derived from experimental data. Overall comparison of derived and measured RRCs shows that this algorithm is suitable for processing ground truth data for the purposes of remote data calibration. The second part of this work consists of the evaluation of the predictive visibility model (PVM). The simulated three-dimensional values of optical properties are compared with the measured ones. Preliminary results of comparison are encouraging and show that the PVM can qualitatively predict the evolution of inherent optical properties in littoral waters.

Parallelization of KENO-Va Monte Carlo code

NASA Astrophysics Data System (ADS)

Ramón, Javier; Peña, Jorge

1995-07-01

KENO-Va is a code integrated within the SCALE system developed by Oak Ridge that solves the transport equation through the Monte Carlo Method. It is being used at the Consejo de Seguridad Nuclear (CSN) to perform criticality calculations for fuel storage pools and shipping casks. Two parallel versions of the code: one for shared memory machines and other for distributed memory systems using the message-passing interface PVM have been generated. In both versions the neutrons of each generation are tracked in parallel. In order to preserve the reproducibility of the results in both versions, advanced seeds for random numbers were used. The CONVEX C3440 with four processors and shared memory at CSN was used to implement the shared memory version. A FDDI network of 6 HP9000/735 was employed to implement the message-passing version using proprietary PVM. The speedup obtained was 3.6 in both cases.

Methodologies and systems for heterogeneous concurrent computing

NASA Technical Reports Server (NTRS)

Sunderam, V. S.

1994-01-01

Heterogeneous concurrent computing is gaining increasing acceptance as an alternative or complementary paradigm to multiprocessor-based parallel processing as well as to conventional supercomputing. While algorithmic and programming aspects of heterogeneous concurrent computing are similar to their parallel processing counterparts, system issues, partitioning and scheduling, and performance aspects are significantly different. In this paper, we discuss critical design and implementation issues in heterogeneous concurrent computing, and describe techniques for enhancing its effectiveness. In particular, we highlight the system level infrastructures that are required, aspects of parallel algorithm development that most affect performance, system capabilities and limitations, and tools and methodologies for effective computing in heterogeneous networked environments. We also present recent developments and experiences in the context of the PVM system and comment on ongoing and future work.

Modeling the 1958 Lituya Bay mega-tsunami with a PVM-IFCP GPU-based model

NASA Astrophysics Data System (ADS)

González-Vida, José M.; Arcas, Diego; de la Asunción, Marc; Castro, Manuel J.; Macías, Jorge; Ortega, Sergio; Sánchez-Linares, Carlos; Titov, Vasily

2013-04-01

In this work we present a numerical study, performed in collaboration with the NOAA Center for Tsunami Research (USA), that uses a GPU version of the PVM-IFCP landslide model for the simulation of the 1958 landslide generated tsunami of Lituya Bay. In this model, a layer composed of fluidized granular material is assumed to flow within an upper layer of an inviscid fluid (e. g. water). The model is discretized using a two dimensional PVM-IFCP [Fernández - Castro - Parés. On an Intermediate Field Capturing Riemann Solver Based on a Parabolic Viscosity Matrix for the Two-Layer Shallow Water System, J. Sci. Comput., 48 (2011):117-140] finite volume scheme implemented on GPU cards for increasing the speed-up. This model has been previously validated by using the two-dimensional physical laboratory experiments data from H. Fritz [Lituya Bay Landslide Impact Generated Mega-Tsunami 50th Anniversary. Pure Appl. Geophys., 166 (2009) pp. 153-175]. In the present work, the first step was to reconstruct the topobathymetry of the Lituya Bay before this event ocurred, this is based on USGS geological surveys data. Then, a sensitivity analysis of some model parameters has been performed in order to determine the parameters that better fit to reality, when model results are compared against available event data, as run-up areas. In this presentation, the reconstruction of the pre-tsunami scenario will be shown, a detailed simulation of the tsunami presented and several comparisons with real data (runup, wave height, etc.) shown.

Long-term live imaging reveals cytosolic immune responses of host hepatocytes against Plasmodium infection and parasite escape mechanisms

PubMed Central

Prado, Monica; Eickel, Nina; De Niz, Mariana; Heitmann, Anna; Agop-Nersesian, Carolina; Wacker, Rahel; Schmuckli-Maurer, Jacqueline; Caldelari, Reto; Janse, Chris J; Khan, Shahid M; May, Jürgen; Meyer, Christian G; Heussler, Volker T

2015-01-01

Plasmodium parasites are transmitted by Anopheles mosquitoes to the mammalian host and actively infect hepatocytes after passive transport in the bloodstream to the liver. In their target host hepatocyte, parasites reside within a parasitophorous vacuole (PV). In the present study it was shown that the parasitophorous vacuole membrane (PVM) can be targeted by autophagy marker proteins LC3, ubiquitin, and SQSTM1/p62 as well as by lysosomes in a process resembling selective autophagy. The dynamics of autophagy marker proteins in individual Plasmodium berghei-infected hepatocytes were followed by live imaging throughout the entire development of the parasite in the liver. Although the host cell very efficiently recognized the invading parasite in its vacuole, the majority of parasites survived this initial attack. Successful parasite development correlated with the gradual loss of all analyzed autophagy marker proteins and associated lysosomes from the PVM. However, other autophagic events like nonselective canonical autophagy in the host cell continued. This was indicated as LC3, although not labeling the PVM anymore, still localized to autophagosomes in the infected host cell. It appears that growing parasites even benefit from this form of nonselective host cell autophagy as an additional source of nutrients, as in host cells deficient for autophagy, parasite growth was retarded and could partly be rescued by the supply of additional amino acid in the medium. Importantly, mouse infections with P. berghei sporozoites confirmed LC3 dynamics, the positive effect of autophagy activation on parasite growth, and negative effects upon autophagy inhibition. PMID:26208778

Visual Computing Environment

NASA Technical Reports Server (NTRS)

Lawrence, Charles; Putt, Charles W.

1997-01-01

The Visual Computing Environment (VCE) is a NASA Lewis Research Center project to develop a framework for intercomponent and multidisciplinary computational simulations. Many current engineering analysis codes simulate various aspects of aircraft engine operation. For example, existing computational fluid dynamics (CFD) codes can model the airflow through individual engine components such as the inlet, compressor, combustor, turbine, or nozzle. Currently, these codes are run in isolation, making intercomponent and complete system simulations very difficult to perform. In addition, management and utilization of these engineering codes for coupled component simulations is a complex, laborious task, requiring substantial experience and effort. To facilitate multicomponent aircraft engine analysis, the CFD Research Corporation (CFDRC) is developing the VCE system. This system, which is part of NASA's Numerical Propulsion Simulation System (NPSS) program, can couple various engineering disciplines, such as CFD, structural analysis, and thermal analysis. The objectives of VCE are to (1) develop a visual computing environment for controlling the execution of individual simulation codes that are running in parallel and are distributed on heterogeneous host machines in a networked environment, (2) develop numerical coupling algorithms for interchanging boundary conditions between codes with arbitrary grid matching and different levels of dimensionality, (3) provide a graphical interface for simulation setup and control, and (4) provide tools for online visualization and plotting. VCE was designed to provide a distributed, object-oriented environment. Mechanisms are provided for creating and manipulating objects, such as grids, boundary conditions, and solution data. This environment includes parallel virtual machine (PVM) for distributed processing. Users can interactively select and couple any set of codes that have been modified to run in a parallel distributed fashion on a cluster of heterogeneous workstations. A scripting facility allows users to dictate the sequence of events that make up the particular simulation.

Plasmacytoid Dendritic Cells Promote Host Defense Against Acute Pneumovirus Infection via the TLR7-MyD88-Dependent Signaling Pathway

PubMed Central

Davidson, Sophia; Kaiko, Gerard; Loh, Zhixuan; Lalwani, Amit; Zhang, Vivian; Spann, Kirsten; Foo, Shen Yun; Hansbro, Nicole; Uematsu, Satoshi; Akira, Shizuo; Matthaei, Klaus I.; Rosenberg, Helene F.; Foster, Paul S.; Phipps, Simon

2012-01-01

Human respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infection in infants. In human infants, plasmacytoid dendritic cells (pDC) are recruited to the nasal compartment during infection and initiate host defense through the secretion of type I IFN, IL-12 and IL-6. However, RSV-infected pDCs are refractory to TLR7-mediated activation. Here, we used the rodent-specific pathogen, pneumonia virus of mice (PVM), to determine the contribution of pDC and TLR7-signaling to the development of the innate inflammatory and early adaptive immune response. In wild-type (WT) but not TLR7- or myeloid differentiation protein 88 (MyD88)-deficient mice, PVM inoculation led to a marked infiltration of pDCs and increased expression of type I, II and III IFNs. The delayed induction of IFNs in the absence of TLR7 or MyD88 was associated with a diminished innate inflammatory response and augmented virus recovery from lung tissue. In the absence of TLR7, PVM-specific CD8+ T cell cytokine production was abrogated. The adoptive transfer of TLR7-sufficient but not TLR7-deficient pDC to TLR7-gene-deleted mice recapitulated the antiviral responses observed in WT mice and promoted virus clearance. In summary, TLR7-mediated signaling by pDC is required for appropriate innate responses to acute pneumovirus infection. It is conceivable that as-yet-unidentified defects in the TLR7 signaling pathway may be associated with elevated levels of RSV-associated morbidity and mortality among otherwise healthy human infants. PMID:21482736

Culture media-based selection of endothelial cells, pericytes, and perivascular-resident macrophage-like melanocytes from the young mouse vestibular system.

PubMed

Zhang, Jinhui; Chen, Songlin; Cai, Jing; Hou, Zhiqiang; Wang, Xiaohan; Kachelmeier, Allan; Shi, Xiaorui

2017-03-01

The vestibular blood-labyrinth barrier (BLB) is comprised of perivascular-resident macrophage-like melanocytes (PVM/Ms) and pericytes (PCs), in addition to endothelial cells (ECs) and basement membrane (BM), and bears strong resemblance to the cochlear BLB in the stria vascularis. Over the past few decades, in vitro cell-based models have been widely used in blood-brain barrier (BBB) and blood-retina barrier (BRB) research, and have proved to be powerful tools for studying cell-cell interactions in their respective organs. Study of both the vestibular and strial BLB has been limited by the unavailability of primary culture cells from these barriers. To better understand how barrier component cells interact in the vestibular system to control BLB function, we developed a novel culture medium-based method for obtaining EC, PC, and PVM/M primary cells from tiny explants of the semicircular canal, sacculus, utriculus, and ampullae tissue of young mouse ears at post-natal age 8-12 d. Each phenotype is grown in a specific culture medium which selectively supports the phenotype in a mixed population of vestibular cell types. The unwanted phenotypes do not survive passaging. The protocol does not require additional equipment or special enzyme treatment. The harvesting process takes less than 2 h. Primary cell types are generated within 7-10 d. The primary culture ECs, PCs, and PVM/M shave consistent phenotypes more than 90% pure after two passages (∼ 3 weeks). The highly purified primary cell lines can be used for studying cell-cell interactions, barrier permeability, and angiogenesis. Copyright © 2017 Elsevier B.V. All rights reserved.

RAGE deficiency predisposes mice to virus-induced paucigranulocytic asthma

PubMed Central

Arikkatt, Jaisy; Ullah, Md Ashik; Short, Kirsty Renfree; Zhang, Vivan; Gan, Wan Jun; Loh, Zhixuan; Werder, Rhiannon B; Simpson, Jennifer; Sly, Peter D; Mazzone, Stuart B; Spann, Kirsten M; Ferreira, Manuel AR; Upham, John W; Sukkar, Maria B; Phipps, Simon

2017-01-01

Asthma is a chronic inflammatory disease. Although many patients with asthma develop type-2 dominated eosinophilic inflammation, a number of individuals develop paucigranulocytic asthma, which occurs in the absence of eosinophilia or neutrophilia. The aetiology of paucigranulocytic asthma is unknown. However, both respiratory syncytial virus (RSV) infection and mutations in the receptor for advanced glycation endproducts (RAGE) are risk factors for asthma development. Here, we show that RAGE deficiency impairs anti-viral immunity during an early-life infection with pneumonia virus of mice (PVM; a murine analogue of RSV). The elevated viral load was associated with the release of high mobility group box-1 (HMGB1) which triggered airway smooth muscle remodelling in early-life. Re-infection with PVM in later-life induced many of the cardinal features of asthma in the absence of eosinophilic or neutrophilic inflammation. Anti-HMGB1 mitigated both early-life viral disease and asthma-like features, highlighting HMGB1 as a possible novel therapeutic target. DOI: http://dx.doi.org/10.7554/eLife.21199.001 PMID:28099113

Sensory Neuron Fates Are Distinguished by a Transcriptional Switch that Regulates Dendrite Branch Stabilization

PubMed Central

Smith, Cody J.; O’Brien, Timothy; Chatzigeorgiou, Marios; Spencer, W. Clay; Feingold-Link, Elana; Husson, Steven J.; Hori, Sayaka; Mitani, Shohei; Gottschalk, Alexander; Schafer, William R.; Miller, David M.

2013-01-01

SUMMARY Sensory neurons adopt distinct morphologies and functional modalities to mediate responses to specific stimuli. Transcription factors and their downstream effectors orchestrate this outcome but are incompletely defined. Here, we show that different classes of mechanosensory neurons in C. elegans are distinguished by the combined action of the transcription factors MEC-3, AHR-1, and ZAG-1. Low levels of MEC-3 specify the elaborate branching pattern of PVD nociceptors, whereas high MEC-3 is correlated with the simple morphology of AVM and PVM touch neurons. AHR-1 specifies AVM touch neuron fate by elevating MEC-3 while simultaneously blocking expression of nociceptive genes such as the MEC-3 target, the claudin-like membrane protein HPO-30, that promotes the complex dendritic branching pattern of PVD. ZAG-1 exercises a parallel role to prevent PVM from adopting the PVD fate. The conserved dendritic branching function of the Drosophila AHR-1 homolog, Spineless, argues for similar pathways in mammals. PMID:23889932

Parallel computation and the Basis system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Smith, G.R.

1992-12-16

A software package has been written that can facilitate efforts to develop powerful, flexible, and easy-to-use programs that can run in single-processor, massively parallel, and distributed computing environments. Particular attention has been given to the difficulties posed by a program consisting of many science packages that represent subsystems of a complicated, coupled system. Methods have been found to maintain independence of the packages by hiding data structures without increasing the communication costs in a parallel computing environment. Concepts developed in this work are demonstrated by a prototype program that uses library routines from two existing software systems, Basis and Parallelmore » Virtual Machine (PVM). Most of the details of these libraries have been encapsulated in routines and macros that could be rewritten for alternative libraries that possess certain minimum capabilities. The prototype software uses a flexible master-and-slaves paradigm for parallel computation and supports domain decomposition with message passing for partitioning work among slaves. Facilities are provided for accessing variables that are distributed among the memories of slaves assigned to subdomains. The software is named PROTOPAR.« less

Parallel computation and the basis system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Smith, G.R.

1993-05-01

A software package has been written that can facilitate efforts to develop powerful, flexible, and easy-to use programs that can run in single-processor, massively parallel, and distributed computing environments. Particular attention has been given to the difficulties posed by a program consisting of many science packages that represent subsystems of a complicated, coupled system. Methods have been found to maintain independence of the packages by hiding data structures without increasing the communications costs in a parallel computing environment. Concepts developed in this work are demonstrated by a prototype program that uses library routines from two existing software systems, Basis andmore » Parallel Virtual Machine (PVM). Most of the details of these libraries have been encapsulated in routines and macros that could be rewritten for alternative libraries that possess certain minimum capabilities. The prototype software uses a flexible master-and-slaves paradigm for parallel computation and supports domain decomposition with message passing for partitioning work among slaves. Facilities are provided for accessing variables that are distributed among the memories of slaves assigned to subdomains. The software is named PROTOPAR.« less

Computational strategies for three-dimensional flow simulations on distributed computer systems. Ph.D. Thesis Semiannual Status Report, 15 Aug. 1993 - 15 Feb. 1994

NASA Technical Reports Server (NTRS)

Weed, Richard Allen; Sankar, L. N.

1994-01-01

An increasing amount of research activity in computational fluid dynamics has been devoted to the development of efficient algorithms for parallel computing systems. The increasing performance to price ratio of engineering workstations has led to research to development procedures for implementing a parallel computing system composed of distributed workstations. This thesis proposal outlines an ongoing research program to develop efficient strategies for performing three-dimensional flow analysis on distributed computing systems. The PVM parallel programming interface was used to modify an existing three-dimensional flow solver, the TEAM code developed by Lockheed for the Air Force, to function as a parallel flow solver on clusters of workstations. Steady flow solutions were generated for three different wing and body geometries to validate the code and evaluate code performance. The proposed research will extend the parallel code development to determine the most efficient strategies for unsteady flow simulations.

DIALOG: An executive computer program for linking independent programs

NASA Technical Reports Server (NTRS)

Glatt, C. R.; Hague, D. S.; Watson, D. A.

1973-01-01

A very large scale computer programming procedure called the DIALOG Executive System has been developed for the Univac 1100 series computers. The executive computer program, DIALOG, controls the sequence of execution and data management function for a library of independent computer programs. Communication of common information is accomplished by DIALOG through a dynamically constructed and maintained data base of common information. The unique feature of the DIALOG Executive System is the manner in which computer programs are linked. Each program maintains its individual identity and as such is unaware of its contribution to the large scale program. This feature makes any computer program a candidate for use with the DIALOG Executive System. The installation and use of the DIALOG Executive System are described at Johnson Space Center.

DIALOG: An executive computer program for linking independent programs

NASA Technical Reports Server (NTRS)

Glatt, C. R.; Hague, D. S.; Watson, D. A.

1973-01-01

A very large scale computer programming procedure called the DIALOG executive system was developed for the CDC 6000 series computers. The executive computer program, DIALOG, controls the sequence of execution and data management function for a library of independent computer programs. Communication of common information is accomplished by DIALOG through a dynamically constructed and maintained data base of common information. Each computer program maintains its individual identity and is unaware of its contribution to the large scale program. This feature makes any computer program a candidate for use with the DIALOG executive system. The installation and uses of the DIALOG executive system are described.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Painter, J.; McCormick, P.; Krogh, M.

This paper presents the ACL (Advanced Computing Lab) Message Passing Library. It is a high throughput, low latency communications library, based on Thinking Machines Corp.`s CMMD, upon which message passing applications can be built. The library has been implemented on the Cray T3D, Thinking Machines CM-5, SGI workstations, and on top of PVM.

A Workstation Farm Optimized for Monte Carlo Shell Model Calculations : Alphleet

NASA Astrophysics Data System (ADS)

Watanabe, Y.; Shimizu, N.; Haruyama, S.; Honma, M.; Mizusaki, T.; Taketani, A.; Utsuno, Y.; Otsuka, T.

We have built a workstation farm named ``Alphleet" which consists of 140 COMPAQ's Alpha 21264 CPUs, for Monte Carlo Shell Model (MCSM) calculations. It has achieved more than 90 % scalable performance with 140 CPUs when the MCSM calculation with PVM and 61.2 Gflops of LINPACK.

Understanding the Importance and Practice of Credible Leadership at Program Executive Office Ground Combat Systems (PEO GCS) and Program Executive Office Combat Support and Combat Service Support (PEO CS and CSS)

DTIC Science & Technology

2017-03-30

and Program Executive Office Combat Support and Combat Service Support (PEO CS&CSS) Chad P. Stocker March 30, 2017 Submitted to...to Defense Acquisition University in partial fulfillment of the requirement of the Senior Service College Fellowship CREDIBLE LEADERSHIP AT PEO...of Credible Leadership at Program Executive Office Ground Combat Systems (PEO GCS) and Program Executive Office Combat Support and Combat Service

Chronic Neuropsychological Sequelae of Cholinesterase Inhibitors in the Absence of Structural Brain Damage: Two Cases of Acute Poisoning

PubMed Central

Roldán-Tapia, Lola; Leyva, Antonia; Laynez, Francisco; Santed, Fernando Sánchez

2005-01-01

Here we describe two cases of carbamate poisoning. Patients AMF and PVM were accidentally poisoned by cholinesterase inhibitors. The medical diagnosis in both cases was overcholinergic syndrome, as demonstrated by exposure to cholinesterase inhibitors. The widespread use of cholinesterase inhibitors, especially as pesticides, produces a great number of human poisoning events annually. The main known neurotoxic effect of these substances is cholinesterase inhibition, which causes cholinergic overstimulation. Once AMF and PVM had recovered from acute intoxication, they were subjected to extensive neuropsychological evaluation 3 and 12 months after the poisoning event. These assessments point to a cognitive deficit in attention, memory, perceptual, and motor domains 3 months after intoxication. One year later these sequelae remained, even though the brain magnetic resonance imaging (MRI) and computed tomography (CT) scans were interpreted as being within normal limits. We present these cases as examples of neuropsychological profiles of long-term sequelae related to acute poisoning by cholinesterase inhibitor pesticides and show the usefulness of neuropsychological assessment in detecting central nervous system dysfunction in the absence of biochemical or structural markers. PMID:15929901

A Survey of New Trends in Symbolic Execution for Software Testing and Analysis

NASA Technical Reports Server (NTRS)

Pasareanu, Corina S.; Visser, Willem

2009-01-01

Symbolic execution is a well-known program analysis technique which represents values of program inputs with symbolic values instead of concrete (initialized) data and executes the program by manipulating program expressions involving the symbolic values. Symbolic execution has been proposed over three decades ago but recently it has found renewed interest in the research community, due in part to the progress in decision procedures, availability of powerful computers and new algorithmic developments. We provide a survey of some of the new research trends in symbolic execution, with particular emphasis on applications to test generation and program analysis. We first describe an approach that handles complex programming constructs such as input data structures, arrays, as well as multi-threading. We follow with a discussion of abstraction techniques that can be used to limit the (possibly infinite) number of symbolic configurations that need to be analyzed for the symbolic execution of looping programs. Furthermore, we describe recent hybrid techniques that combine concrete and symbolic execution to overcome some of the inherent limitations of symbolic execution, such as handling native code or availability of decision procedures for the application domain. Finally, we give a short survey of interesting new applications, such as predictive testing, invariant inference, program repair, analysis of parallel numerical programs and differential symbolic execution.

Directed Incremental Symbolic Execution

NASA Technical Reports Server (NTRS)

Person, Suzette; Yang, Guowei; Rungta, Neha; Khurshid, Sarfraz

2011-01-01

The last few years have seen a resurgence of interest in the use of symbolic execution -- a program analysis technique developed more than three decades ago to analyze program execution paths. Scaling symbolic execution and other path-sensitive analysis techniques to large systems remains challenging despite recent algorithmic and technological advances. An alternative to solving the problem of scalability is to reduce the scope of the analysis. One approach that is widely studied in the context of regression analysis is to analyze the differences between two related program versions. While such an approach is intuitive in theory, finding efficient and precise ways to identify program differences, and characterize their effects on how the program executes has proved challenging in practice. In this paper, we present Directed Incremental Symbolic Execution (DiSE), a novel technique for detecting and characterizing the effects of program changes. The novelty of DiSE is to combine the efficiencies of static analysis techniques to compute program difference information with the precision of symbolic execution to explore program execution paths and generate path conditions affected by the differences. DiSE is a complementary technique to other reduction or bounding techniques developed to improve symbolic execution. Furthermore, DiSE does not require analysis results to be carried forward as the software evolves -- only the source code for two related program versions is required. A case-study of our implementation of DiSE illustrates its effectiveness at detecting and characterizing the effects of program changes.

The Demand and Supply of University-Based Executive Education. GMAC Occasional Papers.

ERIC Educational Resources Information Center

Johnson, Terry R.; And Others

The results of a study of the market for university-based education programs for executives and managers is presented. Study objectives were to profile corporate use of various executive and management education programs, profile characteristics of university-based executive education programs currently offered, and identify trends and unmet needs…

5 CFR 412.302 - Criteria for a Senior Executive Service candidate development program (SESCDP).

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Criteria for a Senior Executive Service... MANAGEMENT CIVIL SERVICE REGULATIONS SUPERVISORY, MANAGEMENT, AND EXECUTIVE DEVELOPMENT Senior Executive Service Candidate Development Programs § 412.302 Criteria for a Senior Executive Service candidate...

Delivering Savings with Open Architecture and Product Lines

DTIC Science & Technology

2011-04-30

p.m. Chair: Christopher Deegan , Executive Director, Program Executive Office for Integrated Warfare Systems Delivering Savings with Open...Architectures Walt Scacchi and Thomas Alspaugh, Institute for Software Research Christopher Deegan —Executive Director, Program Executive Officer...Integrated Warfare Systems (PEO IWS). Mr. Deegan directs the development, acquisition, and fleet support of 150 combat weapon system programs managed by 350

Atomicity violation detection using access interleaving invariants

DOEpatents

Zhou, Yuanyuan; Lu, Shan; Tucek, Joseph Andrew

2013-09-10

During execution of a program, the situation where the atomicity of a pair of instructions that are to be executed atomically is violated is identified, and a bug is detected as occurring in the program at the pair of instructions. The pairs of instructions that are to be executed atomically can be identified in different manners, such as by executing a program multiple times and using the results of those executions to automatically identify the pairs of instructions.

Effectiveness of Therapeutic Programs for Students with ADHD with Executive Function Deficits

ERIC Educational Resources Information Center

Chaimaha, Napalai; Sriphetcharawut, Sarinya; Lersilp, Suchitporn; Chinchai, Supaporn

2017-01-01

The purpose of this study was to investigate the effectiveness of therapeutic programs, an executive function training program and a collaborative program, for students with attention-deficit/hyperactivity disorder (ADHD) with executive function deficits (EFDs), especially regarding working memory, planning, and monitoring. The participants were…

Development and Application of a Parallel LCAO Cluster Method

NASA Astrophysics Data System (ADS)

Patton, David C.

1997-08-01

CPU intensive steps in the SCF electronic structure calculations of clusters and molecules with a first-principles LCAO method have been fully parallelized via a message passing paradigm. Identification of the parts of the code that are composed of many independent compute-intensive steps is discussed in detail as they are the most readily parallelized. Most of the parallelization involves spatially decomposing numerical operations on a mesh. One exception is the solution of Poisson's equation which relies on distribution of the charge density and multipole methods. The method we use to parallelize this part of the calculation is quite novel and is covered in detail. We present a general method for dynamically load-balancing a parallel calculation and discuss how we use this method in our code. The results of benchmark calculations of the IR and Raman spectra of PAH molecules such as anthracene (C_14H_10) and tetracene (C_18H_12) are presented. These benchmark calculations were performed on an IBM SP2 and a SUN Ultra HPC server with both MPI and PVM. Scalability and speedup for these calculations is analyzed to determine the efficiency of the code. In addition, performance and usage issues for MPI and PVM are presented.

FEASIBILITY STUDY ON EXECUTIVE PROGRAM DEVELOPMENT FOR BASIN ECOSYSTEMS MODELING

EPA Science Inventory

The project was undertaken in order to provide a feasibility study in developing and implementing a complete executive program to interface automatically various basin-wide water quality models for use by relatively inexperienced modelers. This executive program should ultimately...

On the Information Content of Program Traces

NASA Technical Reports Server (NTRS)

Frumkin, Michael; Hood, Robert; Yan, Jerry; Saini, Subhash (Technical Monitor)

1998-01-01

Program traces are used for analysis of program performance, memory utilization, and communications as well as for program debugging. The trace contains records of execution events generated by monitoring units inserted into the program. The trace size limits the resolution of execution events and restricts the user's ability to analyze the program execution. We present a study of the information content of program traces and develop a coding scheme which reduces the trace size to the limit given by the trace entropy. We apply the coding to the traces of AIMS instrumented programs executed on the IBM SPA and the SCSI Power Challenge and compare it with other coding methods. Our technique shows size of the trace can be reduced by more than a factor of 5.

Application driven interface generation for EASIE. M.S. Thesis

NASA Technical Reports Server (NTRS)

Kao, Ya-Chen

1992-01-01

The Environment for Application Software Integration and Execution (EASIE) provides a user interface and a set of utility programs which support the rapid integration and execution of analysis programs about a central relational database. EASIE provides users with two basic modes of execution. One of them is a menu-driven execution mode, called Application-Driven Execution (ADE), which provides sufficient guidance to review data, select a menu action item, and execute an application program. The other mode of execution, called Complete Control Execution (CCE), provides an extended executive interface which allows in-depth control of the design process. Currently, the EASIE system is based on alphanumeric techniques only. It is the purpose of this project to extend the flexibility of the EASIE system in the ADE mode by implementing it in a window system. Secondly, a set of utilities will be developed to assist the experienced engineer in the generation of an ADE application.

7 CFR 1944.409 - Executive Order 12372.

Code of Federal Regulations, 2011 CFR

2011-01-01

...) PROGRAM REGULATIONS (CONTINUED) HOUSING Self-Help Technical Assistance Grants § 1944.409 Executive Order 12372. The self-help program is subject to the provision of Executive Order 12372 which requires... (available in any Agency office), new applicants for the self-help program must submit their Statement of...

78 FR 934 - 37 Wilton Road, Milford LLC, and 282 Route 101 LLC, PVM Commercial Center, LLC; Notice of...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-07

... printed on the eLibrary link of Commission's Web site at http://www.ferc.gov/docs-filing/elibrary.asp... Commission's Web site under http://www.ferc.gov/docs-filing/efiling.asp . Commenters can submit brief comments up to 6,000 characters, without prior registration, using the eComment system at http://www.ferc...

Higher-Performance Executives: Bringing Executive Development Programs Into Balance

ERIC Educational Resources Information Center

Gilad, Benjamin; Chussil, Mark

2013-01-01

Executive development programs teach various skills deemed important in future leaders and help shape future leadership and its performance. However, they are often excessively focused on competencies required for dealing with internal issues and relationships. They do a much less admirable job preparing future executives for the unique skills…

Carnegie Mellon University's MMM program: management education for 21st-century physicians.

PubMed

Korevaar, W C; Pearson, R W

2001-01-01

The number and types of executive and graduate-level management programs for physicians have exploded in recent years. These programs take on a variety of formats, ranging from executive seminars to master's-level degree programs. Options for physicians obtaining the master's degree tend to be either regionally based programs in traditional evening classes or nationally based programs that combine executive education formats with distance education. This paper examines a nationally based program - the Master of Medical Management (MMM) - from the perspectives of an administrator and a graduate of the program. It offers reasons for the growth of similar programs and data from students enrolled in the Carnegie Mellon University MMM program. The paper also examines educational outcomes in the form of behavioral competencies that the physicians acquired in the program. It concludes with reflections on the future of the MMM and related programs for physician executives in the 21st century.

Evaluating Market Orientation of an Executive MBA Program.

ERIC Educational Resources Information Center

Dubas, Khalid M.; Ghani, Waqar I.; Davis, Stanley; Strong, James T.

1998-01-01

A study assessed the market orientation of the executive Master's in Business Administration (MBA) program at Saint Joseph's University (Pennsylvania) in terms of 12 skills and knowledge areas that reflect effective managerial performance and the student-executives' perceptions of program strengths and weaknesses in delivering these skills.…

Joint Exercise Program: DOD Needs to Take Steps to Improve the Quality of Funding Data

DTIC Science & Technology

2017-02-01

technology systems—the Joint Training Information Management System (JTIMS) and the Execution Management System—to manage the execution of the Joint...Exercise Program, but does not have assurance that funding execution data in the Execution Management System are reliable. JTIMS is the system of record...for the Joint Exercise Program that combatant commanders use to plan and manage their joint training exercises. GAO observed significant variation

Memoized Symbolic Execution

NASA Technical Reports Server (NTRS)

Yang, Guowei; Pasareanu, Corina S.; Khurshid, Sarfraz

2012-01-01

This paper introduces memoized symbolic execution (Memoise), a novel approach for more efficient application of forward symbolic execution, which is a well-studied technique for systematic exploration of program behaviors based on bounded execution paths. Our key insight is that application of symbolic execution often requires several successive runs of the technique on largely similar underlying problems, e.g., running it once to check a program to find a bug, fixing the bug, and running it again to check the modified program. Memoise introduces a trie-based data structure that stores the key elements of a run of symbolic execution. Maintenance of the trie during successive runs allows re-use of previously computed results of symbolic execution without the need for re-computing them as is traditionally done. Experiments using our prototype embodiment of Memoise show the benefits it holds in various standard scenarios of using symbolic execution, e.g., with iterative deepening of exploration depth, to perform regression analysis, or to enhance coverage.

5 CFR 412.301 - Obtaining approval to conduct a Senior Executive Service candidate development program (SESCDP).

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Obtaining approval to conduct a Senior... DEVELOPMENT Senior Executive Service Candidate Development Programs § 412.301 Obtaining approval to conduct a Senior Executive Service candidate development program (SESCDP). (a) An SESCDP is an OPM-approved...

29 CFR 1608.5 - Affirmative action compliance programs under Executive Order No. 11246, as amended.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 29 Labor 4 2011-07-01 2011-07-01 false Affirmative action compliance programs under Executive... EMPLOYMENT OPPORTUNITY COMMISSION AFFIRMATIVE ACTION APPROPRIATE UNDER TITLE VII OF THE CIVIL RIGHTS ACT OF 1964, AS AMENDED § 1608.5 Affirmative action compliance programs under Executive Order No. 11246, as...

29 CFR 1608.5 - Affirmative action compliance programs under Executive Order No. 11246, as amended.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 4 2010-07-01 2010-07-01 false Affirmative action compliance programs under Executive... EMPLOYMENT OPPORTUNITY COMMISSION AFFIRMATIVE ACTION APPROPRIATE UNDER TITLE VII OF THE CIVIL RIGHTS ACT OF 1964, AS AMENDED § 1608.5 Affirmative action compliance programs under Executive Order No. 11246, as...

Virtual Microscopy: A Useful Tool for Meeting Evolving Challenges in the Veterinary Medical Curriculum

NASA Astrophysics Data System (ADS)

Kogan, Lori R.; Dowers, Kristy L.; Cerda, Jacey R.; Schoenfeld-Tacher, Regina M.; Stewart, Sherry M.

2014-12-01

Veterinary schools, similar to many professional health programs, face a myriad of evolving challenges in delivering their professional curricula including expansion of class size, costs to maintain expensive laboratories, and increased demands on veterinary educators to use curricular time efficiently and creatively. Additionally, exponential expansion of the knowledge base through ongoing biomedical research, educational goals to increase student engagement and clinical reasoning earlier in the curriculum, and students' desire to access course materials and enhance their educational experience through the use of technology all support the need to reassess traditional microscope laboratories within Professional Veterinary Medical (PVM) educational programs. While there is clear justification for teaching veterinary students how to use a microscope for clinical evaluation of cytological preparations (i.e., complete blood count, urinalysis, fecal analysis, fine needle aspirates, etc.), virtual microscopy may be a viable alternative to using light microscopy for teaching and learning fundamental histological concepts. This article discusses results of a survey given to assess Professional Veterinary Medical students' perceptions of using virtual microscope for learning basic histology/microscopic anatomy and implications of these results for using virtual microscopy as a pedagogical tool in teaching first-year Professional Veterinary Medical students' basic histology.

Performance Metrics for Monitoring Parallel Program Executions

NASA Technical Reports Server (NTRS)

Sarukkai, Sekkar R.; Gotwais, Jacob K.; Yan, Jerry; Lum, Henry, Jr. (Technical Monitor)

1994-01-01

Existing tools for debugging performance of parallel programs either provide graphical representations of program execution or profiles of program executions. However, for performance debugging tools to be useful, such information has to be augmented with information that highlights the cause of poor program performance. Identifying the cause of poor performance necessitates the need for not only determining the significance of various performance problems on the execution time of the program, but also needs to consider the effect of interprocessor communications of individual source level data structures. In this paper, we present a suite of normalized indices which provide a convenient mechanism for focusing on a region of code with poor performance and highlights the cause of the problem in terms of processors, procedures and data structure interactions. All the indices are generated from trace files augmented with data structure information.. Further, we show with the help of examples from the NAS benchmark suite that the indices help in detecting potential cause of poor performance, based on augmented execution traces obtained by monitoring the program.

Generating and executing programs for a floating point single instruction multiple data instruction set architecture

DOEpatents

Gschwind, Michael K

2013-04-16

Mechanisms for generating and executing programs for a floating point (FP) only single instruction multiple data (SIMD) instruction set architecture (ISA) are provided. A computer program product comprising a computer recordable medium having a computer readable program recorded thereon is provided. The computer readable program, when executed on a computing device, causes the computing device to receive one or more instructions and execute the one or more instructions using logic in an execution unit of the computing device. The logic implements a floating point (FP) only single instruction multiple data (SIMD) instruction set architecture (ISA), based on data stored in a vector register file of the computing device. The vector register file is configured to store both scalar and floating point values as vectors having a plurality of vector elements.

5 CFR 412.301 - Obtaining approval to conduct a Senior Executive Service candidate development program (SESCDP).

Code of Federal Regulations, 2011 CFR

2011-01-01

... training program designed to develop the executive qualifications of employees with strong executive... career appointment without further competition to any SES position for which he or she meets the...

Design and optimization of production parameters for boric acid crystals with the crystallization process in an MSMPR crystallizer using FBRM® and PVM® technologies

NASA Astrophysics Data System (ADS)

Kutluay, Sinan; Şahin, Ömer; Ceyhan, A. Abdullah; İzgi, M. Sait

2017-06-01

In crystallization studies, newly developed technologies, such as Focused Beam Reflectance Measurement (FBRM) and Particle Vision and Measurement (PVM) are applied for determining on-line monitoring of a representation of the Chord Length Distribution (CLD) and observe the photographs of crystals respectively; moreover recently they are widely used. Properly installed, the FBRM ensures on-line determination of the CLD, which is statistically associated to the Crystal Size Distribution (CSD). In industrial crystallization, CSD and mean crystal size as well as external habit and internal structure are important characteristics for further use of the crystals. In this paper, the effect of residence time, stirring speed, feeding rate, supersaturation level and the polyelectrolytes such as anionic polyacrylamide (APAM) and non-ionic polyacrylamide (NPAM) on the CLD as well as the shape of boric acid crystals were investigated by using the FBRM G600 and the PVM V819 probes respectively in an MSMPR (Mixed Suspension Mixed Product Removal) crystallizer. The CSD and kinetic data were determined experimentally using continuous MSMPR crystallizer running at steady state. The population density of nuclei, the nucleation rate and the growth rate were determined from the experimental population balance distribution when the steady state was reached.

Cytoplasmic remodeling of erythrocyte raft lipids during infection by the human malaria parasite Plasmodium falciparum

PubMed Central

Murphy, Sean C.; Fernandez-Pol, Sebastian; Chung, Paul H.; Prasanna Murthy, S. N.; Milne, Stephen B.; Salomao, Marcela; Brown, H. Alex; Lomasney, Jon W.; Mohandas, Narla

2007-01-01

Studies of detergent-resistant membrane (DRM) rafts in mature erythrocytes have facilitated identification of proteins that regulate formation of endovacuolar structures such as the parasitophorous vacuolar membrane (PVM) induced by the malaria parasite Plasmodium falciparum. However, analyses of raft lipids have remained elusive because detergents interfere with lipid detection. Here, we use primaquine to perturb the erythrocyte membrane and induce detergent-free buoyant vesicles, which are enriched in cholesterol and major raft proteins flotillin and stomatin and contain low levels of cytoskeleton, all characteristics of raft microdomains. Lipid mass spectrometry revealed that phosphatidylethanolamine and phosphatidylglycerol are depleted in endovesicles while phosphoinositides are highly enriched, suggesting raft-based endovesiculation can be achieved by simple (non–receptor-mediated) mechanical perturbation of the erythrocyte plasma membrane and results in sorting of inner leaflet phospholipids. Live-cell imaging of lipid-specific protein probes showed that phosphatidylinositol (4,5) bisphosphate (PIP2) is highly concentrated in primaquine-induced vesicles, confirming that it is an erythrocyte raft lipid. However, the malarial PVM lacks PIP2, although another raft lipid, phosphatidylserine, is readily detected. Thus, different remodeling/sorting of cytoplasmic raft phospholipids may occur in distinct endovacuoles. Importantly, erythrocyte raft lipids recruited to the invasion junction by mechanical stimulation may be remodeled by the malaria parasite to establish blood-stage infection. PMID:17526861

Local Epidermal Growth Factor Receptor Signaling Mediates the Systemic Pathogenic Effects of Staphylococcus aureus Toxic Shock Syndrome.

PubMed

Breshears, Laura M; Gillman, Aaron N; Stach, Christopher S; Schlievert, Patrick M; Peterson, Marnie L

2016-01-01

Secreted factors of Staphylococcus aureus can activate host signaling from the epidermal growth factor receptor (EGFR). The superantigen toxic shock syndrome toxin-1 (TSST-1) contributes to mucosal cytokine production through a disintegrin and metalloproteinase (ADAM)-mediated shedding of EGFR ligands and subsequent EGFR activation. The secreted hemolysin, α-toxin, can also induce EGFR signaling and directly interacts with ADAM10, a sheddase of EGFR ligands. The current work explores the role of EGFR signaling in menstrual toxic shock syndrome (mTSS), a disease mediated by TSST-1. The data presented show that TSST-1 and α-toxin induce ADAM- and EGFR-dependent cytokine production from human vaginal epithelial cells. TSST-1 and α-toxin also induce cytokine production from an ex vivo porcine vaginal mucosa (PVM) model. EGFR signaling is responsible for the majority of IL-8 production from PVM in response to secreted toxins and live S. aureus. Finally, data are presented demonstrating that inhibition of EGFR signaling with the EGFR-specific tyrosine kinase inhibitor AG1478 significantly increases survival in a rabbit model of mTSS. These data indicate that EGFR signaling is critical for progression of an S. aureus exotoxin-mediated disease and may represent an attractive host target for therapeutics.

The nonstructural proteins of Pneumoviruses are remarkably distinct in substrate diversity and specificity.

PubMed

Ribaudo, Michael; Barik, Sailen

2017-11-06

Interferon (IFN) inhibits viruses by inducing several hundred cellular genes, aptly named 'interferon (IFN)-stimulated genes' (ISGs). The only two RNA viruses of the Pneumovirus genus of the Paramyxoviridae family, namely Respiratory Syncytial Virus (RSV) and Pneumonia Virus of Mice (PVM), each encode two nonstructural (NS) proteins that share no sequence similarity but yet suppress IFN. Since suppression of IFN underlies the ability of these viruses to replicate in the host cells, the mechanism of such suppression has become an important area of research. This Short Report is an important extension of our previous efforts in defining this mechanism. We show that, like their PVM counterparts, the RSV NS proteins also target multiple members of the ISG family. While significantly extending the substrate repertoire of the RSV NS proteins, these results, unexpectedly, also reveal that the target preferences of the NS proteins of the two viruses are entirely different. This is surprising since the two Pneumoviruses are phylogenetically close with similar genome organization and gene function, and the NS proteins of both also serve as suppressors of host IFN response. The finding that the NS proteins of the two highly similar viruses suppress entirely different members of the ISG family raises intriguing questions of pneumoviral NS evolution and mechanism of action.

New views of the Toxoplasma gondii parasitophorous vacuole as revealed by Helium Ion Microscopy (HIM).

PubMed

de Souza, Wanderley; Attias, Marcia

2015-07-01

The Helium Ion Microscope (HIM) is a new technology that uses a highly focused helium ion beam to scan and interact with the sample, which is not coated. The images have resolution and depth of field superior to field emission scanning electron microscopes. In this paper, we used HIM to study LLC-MK2 cells infected with Toxoplasma gondii. These samples were chemically fixed and, after critical point drying, were scraped with adhesive tape to expose the inner structure of the cell and parasitophorous vacuoles. We confirmed some of the previous findings made by field emission-scanning electron microscopy and showed that the surface of the parasite is rich in structures suggestive of secretion, that the nanotubules of the intravacuolar network (IVN) are not always straight, and that bifurcations are less frequent than previously thought. Fusion of the tubules with the parasite membrane or the parasitophorous vacuole membrane (PVM) was also infrequent. Tiny adhesive links were observed for the first time connecting the IVN tubules. The PVM showed openings of various sizes that even allowed the observation of endoplasmic reticulum membranes in the cytoplasm of the host cell. These findings are discussed in relation to current knowledge on the cell biology of T. gondii. Copyright © 2015 Elsevier Inc. All rights reserved.

In Vitro Ability of a Novel Nanohydroxyapatite Oral Rinse to Occlude Dentine Tubules

PubMed Central

Hill, Robert G.; Chen, Xiaohui; Gillam, David G.

2015-01-01

Objectives. The aim of the study was to investigate the ability of a novel nanohydroxyapatite (nHA) desensitizing oral rinse to occlude dentine tubules compared to selected commercially available desensitizing oral rinses. Methods. 25 caries-free extracted molars were sectioned into 1 mm thick dentine discs. The dentine discs (n = 25) were etched with 6% citric acid for 2 minutes and rinsed with distilled water, prior to a 30-second application of test and control oral rinses. Evaluation was by (1) Scanning Electron Microscopy (SEM) of the dentine surface and (2) fluid flow measurements through a dentine disc. Results. Most of the oral rinses failed to adequately cover the dentine surface apart from the nHa oral rinse. However the hydroxyapatite, 1.4% potassium oxalate, and arginine/PVM/MA copolymer oral rinses, appeared to be relatively more effective than the nHA test and negative control rinses (potassium nitrate) in relation to a reduction in fluid flow measurements. Conclusions. Although the novel nHA oral rinse demonstrated the ability to occlude the dentine tubules and reduce the fluid flow measurements, some of the other oral rinses appeared to demonstrate a statistically significant reduction in fluid flow through the dentine disc, in particular the arginine/PVM/MA copolymer oral rinse. PMID:26161093

A Generalized-Compliant-Motion Primitive

NASA Technical Reports Server (NTRS)

Backes, Paul G.

1993-01-01

Computer program bridges gap between planning and execution of compliant robotic motions developed and installed in control system of telerobot. Called "generalized-compliant-motion primitive," one of several task-execution-primitive computer programs, which receives commands from higher-level task-planning programs and executes commands by generating required trajectories and applying appropriate control laws. Program comprises four parts corresponding to nominal motion, compliant motion, ending motion, and monitoring. Written in C language.

Developing the strategic voice of senior nurse executives.

PubMed

Shea, Gregory

2005-01-01

The Wharton School has been offering a senior nurse executive fellowship, sponsored by Johnson & Johnson, for 22 years. As the executive role has changed, the program has evolved. As more chief executive officers and chief operating officers come from the ranks of nursing, the program will continue to change to meet the needs of the future.

Parallel program debugging with flowback analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Choi, Jongdeok.

1989-01-01

This thesis describes the design and implementation of an integrated debugging system for parallel programs running on shared memory multi-processors. The goal of the debugging system is to present to the programmer a graphical view of the dynamic program dependences while keeping the execution-time overhead low. The author first describes the use of flowback analysis to provide information on causal relationship between events in a programs' execution without re-executing the program for debugging. Execution time overhead is kept low by recording only a small amount of trace during a program's execution. He uses semantic analysis and a technique called incrementalmore » tracing to keep the time and space overhead low. As part of the semantic analysis, he uses a static program dependence graph structure that reduces the amount of work done at compile time and takes advantage of the dynamic information produced during execution time. The cornerstone of the incremental tracing concept is to generate a coarse trace during execution and fill incrementally, during the interactive portion of the debugging session, the gap between the information gathered in the coarse trace and the information needed to do the flowback analysis using the coarse trace. Then, he describes how to extend the flowback analysis to parallel programs. The flowback analysis can span process boundaries; i.e., the most recent modification to a shared variable might be traced to a different process than the one that contains the current reference. The static and dynamic program dependence graphs of the individual processes are tied together with synchronization and data dependence information to form complete graphs that represent the entire program.« less

Execution models for mapping programs onto distributed memory parallel computers

NASA Technical Reports Server (NTRS)

Sussman, Alan

1992-01-01

The problem of exploiting the parallelism available in a program to efficiently employ the resources of the target machine is addressed. The problem is discussed in the context of building a mapping compiler for a distributed memory parallel machine. The paper describes using execution models to drive the process of mapping a program in the most efficient way onto a particular machine. Through analysis of the execution models for several mapping techniques for one class of programs, we show that the selection of the best technique for a particular program instance can make a significant difference in performance. On the other hand, the results of benchmarks from an implementation of a mapping compiler show that our execution models are accurate enough to select the best mapping technique for a given program.

41 CFR 102-38.360 - What must an executive agency do to implement the eFAS program?

Code of Federal Regulations, 2011 CFR

2011-01-01

... agency do to implement the eFAS program? 102-38.360 Section 102-38.360 Public Contracts and Property... must an executive agency do to implement the eFAS program? (a) An executive agency must review the... value added services) of the eFAS SCs. Agencies should give full consideration to sales solutions...

41 CFR 102-38.360 - What must an executive agency do to implement the eFAS program?

Code of Federal Regulations, 2010 CFR

2010-07-01

... agency do to implement the eFAS program? 102-38.360 Section 102-38.360 Public Contracts and Property... must an executive agency do to implement the eFAS program? (a) An executive agency must review the... value added services) of the eFAS SCs. Agencies should give full consideration to sales solutions...

41 CFR 102-38.360 - What must an executive agency do to implement the eFAS program?

Code of Federal Regulations, 2014 CFR

2014-01-01

... agency do to implement the eFAS program? 102-38.360 Section 102-38.360 Public Contracts and Property... must an executive agency do to implement the eFAS program? (a) An executive agency must review the... value added services) of the eFAS SCs. Agencies should give full consideration to sales solutions...

41 CFR 102-38.360 - What must an executive agency do to implement the eFAS program?

Code of Federal Regulations, 2013 CFR

2013-07-01

... agency do to implement the eFAS program? 102-38.360 Section 102-38.360 Public Contracts and Property... must an executive agency do to implement the eFAS program? (a) An executive agency must review the... value added services) of the eFAS SCs. Agencies should give full consideration to sales solutions...

41 CFR 102-38.360 - What must an executive agency do to implement the eFAS program?

Code of Federal Regulations, 2012 CFR

2012-01-01

... agency do to implement the eFAS program? 102-38.360 Section 102-38.360 Public Contracts and Property... must an executive agency do to implement the eFAS program? (a) An executive agency must review the... value added services) of the eFAS SCs. Agencies should give full consideration to sales solutions...

7 CFR 1944.409 - Executive Order 12372.

Code of Federal Regulations, 2010 CFR

2010-01-01

...) PROGRAM REGULATIONS (CONTINUED) HOUSING Self-Help Technical Assistance Grants § 1944.409 Executive Order 12372. The self-help program is subject to the provision of Executive Order 12372 which requires... Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS...

75 FR 45667 - Solicitation for a Cooperative Agreement: Strategies for Women Executives in Corrections

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-03

... and ensure it supports the learning process, leadership styles, and required competencies for... cooperative agreement to update its 36-hour Executive Leadership for Women in Corrections program, newly... Executive Leadership for Women in Corrections program [[Page 45668

ANOPP programmer's reference manual for the executive System. [aircraft noise prediction program

NASA Technical Reports Server (NTRS)

Gillian, R. E.; Brown, C. G.; Bartlett, R. W.; Baucom, P. H.

1977-01-01

Documentation for the Aircraft Noise Prediction Program as of release level 01/00/00 is presented in a manual designed for programmers having a need for understanding the internal design and logical concepts of the executive system software. Emphasis is placed on providing sufficient information to modify the system for enhancements or error correction. The ANOPP executive system includes software related to operating system interface, executive control, and data base management for the Aircraft Noise Prediction Program. It is written in Fortran IV for use on CDC Cyber series of computers.

An Architecture-Centric Approach for Acquiring Software-Reliant Systems

DTIC Science & Technology

2011-04-30

Architecture Acquisition Wednesday, May 11, 2011 11:15 a.m. – 12:45 p.m. Chair: Christopher Deegan , Executive Director, Program Executive Office for...Christopher Deegan —Executive Director, Program Executive Officer, Integrated Warfare Systems (PEO IWS). Mr. Deegan directs the development, acquisition, and... Deegan holds a Bachelor of Science degree in Industrial Engineering from Penn State University, University Park, Pennsylvania and a Master of

Advances in the Acquisition of Secure Systems Based on Open Architectures

DTIC Science & Technology

2011-04-30

2011 11:15 a.m. – 12:45 p.m. Chair: Christopher Deegan , Executive Director, Program Executive Office for Integrated Warfare Systems Delivering...Systems Based on Open Architectures Walt Scacchi and Thomas Alspaugh, Institute for Software Research Christopher Deegan —Executive Director, Program...Executive Officer, Integrated Warfare Systems (PEO IWS). Mr. Deegan directs the development, acquisition, and fleet support of 150 combat weapon system

28 CFR 0.143 - Incentive Award Program.

Code of Federal Regulations, 2010 CFR

2010-07-01

....143 Judicial Administration DEPARTMENT OF JUSTICE ORGANIZATION OF THE DEPARTMENT OF JUSTICE... Justice Programs, the Director of the Executive Office for U.S. Attorneys, the Director of the Executive Office for U.S. Trustees, the Director of the Executive Office for Immigration Review, and the Director...

5 CFR 213.3402 - Entire executive civil service; Pathways Programs.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Entire executive civil service; Pathways Programs. 213.3402 Section 213.3402 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS EXCEPTED SERVICE Excepted Schedules Schedule D § 213.3402 Entire executive civil service; Pathways...

5 CFR 213.3402 - Entire executive civil service; Pathways Programs.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Entire executive civil service; Pathways Programs. 213.3402 Section 213.3402 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS EXCEPTED SERVICE Excepted Schedules Schedule D § 213.3402 Entire executive civil service; Pathways...

Generalized Symbolic Execution for Model Checking and Testing

NASA Technical Reports Server (NTRS)

Khurshid, Sarfraz; Pasareanu, Corina; Visser, Willem; Kofmeyer, David (Technical Monitor)

2003-01-01

Modern software systems, which often are concurrent and manipulate complex data structures must be extremely reliable. We present a novel framework based on symbolic execution, for automated checking of such systems. We provide a two-fold generalization of traditional symbolic execution based approaches: one, we define a program instrumentation, which enables standard model checkers to perform symbolic execution; two, we give a novel symbolic execution algorithm that handles dynamically allocated structures (e.g., lists and trees), method preconditions (e.g., acyclicity of lists), data (e.g., integers and strings) and concurrency. The program instrumentation enables a model checker to automatically explore program heap configurations (using a systematic treatment of aliasing) and manipulate logical formulae on program data values (using a decision procedure). We illustrate two applications of our framework: checking correctness of multi-threaded programs that take inputs from unbounded domains with complex structure and generation of non-isomorphic test inputs that satisfy a testing criterion. Our implementation for Java uses the Java PathFinder model checker.

Executive Development Programs: Insights for Planners and Administrators.

ERIC Educational Resources Information Center

Murphy, William H.; Tang, Sidney Sin-Lai

1993-01-01

A survey of 145 sales and marketing professionals identified their preferences and expectations of executive development programs. Most preferred practitioner-taught, single-day programs or seminars over alternative learning formats (teleconferencing, cable television, etc.). (JOW)

Using predicated execution to improve the performance of a dynamically scheduled machine with speculative execution

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chang, P.Y.; Hao, E.; Patt, Y.

Conditional branches incur a severe performance penalty in wide-issue, deeply pipelined processors. Speculative execution and predicated execution are two mechanisms that have been proposed for reducing this penalty. Speculative execution can completely eliminate the penalty associated with a particular branch, but requires accurate branch prediction to be effective. Predicated execution does not require accurate branch prediction to eliminate the branch penalty, but is not applicable to all branches and can increase the latencies within the program. This paper examines the performance benefit of using both mechanisms to reduce the branch execution penalty. Predicated execution is used to handle the hard-to-protectmore » branches and speculative execution is used to handle the remaining branches. The hard-to-predict branches within the program are determined by profiling. We show that this approach can significantly reduce the branch execution penalty suffered by wide-issue processors.« less

Financial Management for Childcare Executive Officers.

ERIC Educational Resources Information Center

Foster-Jorgensen, Karen; Harrington, Angela

This handbook is designed to assist childcare executive officers (CEOs) in managing the finances of their programs. The guide is divided into five sections. Section 1, "Financial Entrepreneurship," advocates the adoption of an entrepreneurial spirit in directors and recommends: (1) becoming the Chief Executive Officer of the program; (2) actively…

28 CFR 0.138 - Federal Bureau of Investigation, Drug Enforcement Administration, Bureau of Alcohol, Tobacco...

Code of Federal Regulations, 2010 CFR

2010-07-01

... Justice Programs, Executive Office for Immigration Review, Executive Office for United States Attorneys... the Office of Justice Programs, the Director of the Executive Office for Immigration Review, the... JUSTICE ORGANIZATION OF THE DEPARTMENT OF JUSTICE Authorizations With Respect to Personnel and Certain...

The Environment for Application Software Integration and Execution (EASIE) version 1.0. Volume 1: Executive overview

NASA Technical Reports Server (NTRS)

Rowell, Lawrence F.; Davis, John S.

1989-01-01

The Environment for Application Software Integration and Execution (EASIE) provides a methodology and a set of software utility programs to ease the task of coordinating engineering design and analysis codes. EASIE was designed to meet the needs of conceptual design engineers that face the task of integrating many stand-alone engineering analysis programs. Using EASIE, programs are integrated through a relational database management system. Volume 1, Executive Overview, gives an overview of the functions provided by EASIE and describes their use. Three operational design systems based upon the EASIE software are briefly described.

CAI-BASIC: A Program to Teach the Programming Language BASIC.

ERIC Educational Resources Information Center

Barry, Thomas Anthony

A computer-assisted instruction (CAI) program was designed which fulfills the objectives of teaching a simple programing language, interpreting student responses, and executing and editing student programs. The CAI-BASIC program is written in FORTRAN IV and executes on IBM-2741 terminals while running under a time-sharing system on an IBM-360-70…

The RWJ Executive Nurse Fellows Program, Part 2: Mentoring for leadership success.

PubMed

Bellack, Janis P; Morjikian, Robin L

2005-12-01

This article is the second in a 3-part series describing the RWJ Executive Nurse Fellows Program, an advanced leadership program for nurses in senior executive roles who aspire to help lead and shape the US healthcare system of the future. Part 1 (October 2005) described the program, its core leadership competencies, and the primary components. This article discusses the mentor experience that is a cornerstone of the 3-year fellowship program. Fellows are encouraged to have this experience with senior-level executives outside of healthcare in order to broaden their leadership perspectives. Examples of these mentor experiences are described from the viewpoints of both fellows and mentors, including successes, challenges, and lessons learned. Part 3 (February 2006) will explain how fellows are required to create a business plan for their leadership project because it is so important for nurse leaders to offer a strong business case for proceeding with anew initiative, service, or program.

A mechanism for efficient debugging of parallel programs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miller, B.P.; Choi, J.D.

1988-01-01

This paper addresses the design and implementation of an integrated debugging system for parallel programs running on shared memory multi-processors (SMMP). The authors describe the use of flowback analysis to provide information on causal relationships between events in a program's execution without re-executing the program for debugging. The authors introduce a mechanism called incremental tracing that, by using semantic analyses of the debugged program, makes the flowback analysis practical with only a small amount of trace generated during execution. The extend flowback analysis to apply to parallel programs and describe a method to detect race conditions in the interactions ofmore » the co-operating processes.« less

Toward synthesizing executable models in biology.

PubMed

Fisher, Jasmin; Piterman, Nir; Bodik, Rastislav

2014-01-01

Over the last decade, executable models of biological behaviors have repeatedly provided new scientific discoveries, uncovered novel insights, and directed new experimental avenues. These models are computer programs whose execution mechanistically simulates aspects of the cell's behaviors. If the observed behavior of the program agrees with the observed biological behavior, then the program explains the phenomena. This approach has proven beneficial for gaining new biological insights and directing new experimental avenues. One advantage of this approach is that techniques for analysis of computer programs can be applied to the analysis of executable models. For example, one can confirm that a model agrees with experiments for all possible executions of the model (corresponding to all environmental conditions), even if there are a huge number of executions. Various formal methods have been adapted for this context, for example, model checking or symbolic analysis of state spaces. To avoid manual construction of executable models, one can apply synthesis, a method to produce programs automatically from high-level specifications. In the context of biological modeling, synthesis would correspond to extracting executable models from experimental data. We survey recent results about the usage of the techniques underlying synthesis of computer programs for the inference of biological models from experimental data. We describe synthesis of biological models from curated mutation experiment data, inferring network connectivity models from phosphoproteomic data, and synthesis of Boolean networks from gene expression data. While much work has been done on automated analysis of similar datasets using machine learning and artificial intelligence, using synthesis techniques provides new opportunities such as efficient computation of disambiguating experiments, as well as the ability to produce different kinds of models automatically from biological data.

A Cache Design to Exploit Structural Locality

DTIC Science & Technology

1991-12-01

memory and secondary storage. Main memory was used to store the instructions and data of an executing pro- gram, while secondary storage held programs ...efficiency of the CPU and faster turnaround of executing programs . In addition to the well known spatial and temporal aspects of locality, Hobart has...identified a third aspect, which he has called structural locality (9). This type of locality is defined as the tendency of an executing program to

Jacobian-free approximate solvers for hyperbolic systems: Application to relativistic magnetohydrodynamics

NASA Astrophysics Data System (ADS)

Castro, Manuel J.; Gallardo, José M.; Marquina, Antonio

2017-10-01

We present recent advances in PVM (Polynomial Viscosity Matrix) methods based on internal approximations to the absolute value function, and compare them with Chebyshev-based PVM solvers. These solvers only require a bound on the maximum wave speed, so no spectral decomposition is needed. Another important feature of the proposed methods is that they are suitable to be written in Jacobian-free form, in which only evaluations of the physical flux are used. This is particularly interesting when considering systems for which the Jacobians involve complex expressions, e.g., the relativistic magnetohydrodynamics (RMHD) equations. On the other hand, the proposed Jacobian-free solvers have also been extended to the case of approximate DOT (Dumbser-Osher-Toro) methods, which can be regarded as simple and efficient approximations to the classical Osher-Solomon method, sharing most of it interesting features and being applicable to general hyperbolic systems. To test the properties of our schemes a number of numerical experiments involving the RMHD equations are presented, both in one and two dimensions. The obtained results are in good agreement with those found in the literature and show that our schemes are robust and accurate, running stable under a satisfactory time step restriction. It is worth emphasizing that, although this work focuses on RMHD, the proposed schemes are suitable to be applied to general hyperbolic systems.

[Differences in momentum development when standing up from a chair between elderly with and without frequent falls history].

PubMed

Guzmán, Rodrigo Antonio; Prado, Hugo Enrique; Porcel Melián, Helvio; Cordier, Benoit

2009-01-01

The momentum of the upper body (UB) during transfer sit-to-stand (STS) could be sensitive to the deterioration of dynamic postural control, and also the risk of falls. The aim of this study is to quantify the differences in the momentum development on UB during the STS in a sample of fall and no-fall elderly subjects. MATERIAL AND MEHODS: The sample consisted of twenty three voluntary elderly subjects (n=23), six elderly adults with antecedents of frequent falls (more than two within a year period) and seventeen without histories of frequent falls. Through a motion analysis system we registered the kinematics of UB during STS, from which we calculated the momentum of UB. The determined analysis variables were: the maximum values of the vertical (P(V)M) and horizontal (P(H)M) lineal momenta, the minimum (L(Max)) and maximum (L(Min)) values of the angular momentum and maximum trunk flexion (thetaM(UB)). No difference was observed in P(H)M, L(Max) and L(Min) (P>0.05) between both groups. However, a significant difference was found for the variable P(V)M (P=0.03) and thetaM(UB) (P=0.03) between both groups. We can conclude that, for the sample studied, the frequent fall condition relates to a smaller capacity to develop vertical momentum and increase flexion of the upper body.

Implications of the Turing machine model of computation for processor and programming language design

NASA Astrophysics Data System (ADS)

Hunter, Geoffrey

2004-01-01

A computational process is classified according to the theoretical model that is capable of executing it; computational processes that require a non-predeterminable amount of intermediate storage for their execution are Turing-machine (TM) processes, while those whose storage are predeterminable are Finite Automation (FA) processes. Simple processes (such as traffic light controller) are executable by Finite Automation, whereas the most general kind of computation requires a Turing Machine for its execution. This implies that a TM process must have a non-predeterminable amount of memory allocated to it at intermediate instants of its execution; i.e. dynamic memory allocation. Many processes encountered in practice are TM processes. The implication for computational practice is that the hardware (CPU) architecture and its operating system must facilitate dynamic memory allocation, and that the programming language used to specify TM processes must have statements with the semantic attribute of dynamic memory allocation, for in Alan Turing"s thesis on computation (1936) the "standard description" of a process is invariant over the most general data that the process is designed to process; i.e. the program describing the process should never have to be modified to allow for differences in the data that is to be processed in different instantiations; i.e. data-invariant programming. Any non-trivial program is partitioned into sub-programs (procedures, subroutines, functions, modules, etc). Examination of the calls/returns between the subprograms reveals that they are nodes in a tree-structure; this tree-structure is independent of the programming language used to encode (define) the process. Each sub-program typically needs some memory for its own use (to store values intermediate between its received data and its computed results); this locally required memory is not needed before the subprogram commences execution, and it is not needed after its execution terminates; it may be allocated as its execution commences, and deallocated as its execution terminates, and if the amount of this local memory is not known until just before execution commencement, then it is essential that it be allocated dynamically as the first action of its execution. This dynamically allocated/deallocated storage of each subprogram"s intermediate values, conforms with the stack discipline; i.e. last allocated = first to be deallocated, an incidental benefit of which is automatic overlaying of variables. This stack-based dynamic memory allocation was a semantic implication of the nested block structure that originated in the ALGOL-60 programming language. AGLOL-60 was a TM language, because the amount of memory allocated on subprogram (block/procedure) entry (for arrays, etc) was computable at execution time. A more general requirement of a Turing machine process is for code generation at run-time; this mandates access to the source language processor (compiler/interpretor) during execution of the process. This fundamental aspect of computer science is important to the future of system design, because it has been overlooked throughout the 55 years since modern computing began in 1048. The popular computer systems of this first half-century of computing were constrained by compile-time (or even operating system boot-time) memory allocation, and were thus limited to executing FA processes. The practical effect was that the distinction between the data-invariant program and its variable data was blurred; programmers had to make trial and error executions, modifying the program"s compile-time constants (array dimensions) to iterate towards the values required at run-time by the data being processed. This era of trial and error computing still persists; it pervades the culture of current (2003) computing practice.

Executive High School Internship Program.

ERIC Educational Resources Information Center

Duperrault, JoAnn Hunter

1992-01-01

The Executive High School Internship Program in Tampa, Florida, involves gifted and talented high school seniors working for a semester as nonpaid administrative assistants in public or private sector organizations. The program's history, recruitment policies, placement practices, and monitoring are reviewed. (DB)

Program Manager as Chief Executive Officer (CEO): Leading with Accountability and Empowerment

DTIC Science & Technology

2009-07-01

Keywords: Program Management, Strategic Leadership, Accountability, Empowerment, Stakeholder Management, Entrepreneurship , Executive Decision...include: executive decision making and ne- gotiation skills, penchant toward entrepreneurship , high ethical standards, and strategic leadership...stakeholders. Negotiation skills are vital in these situations. entrePreneUrshiP Entrepreneurs, by their nature, are opportunistic and risk-taking (Cunning

STAR adaptation of QR algorithm. [program for solving over-determined systems of linear equations

NASA Technical Reports Server (NTRS)

Shah, S. N.

1981-01-01

The QR algorithm used on a serial computer and executed on the Control Data Corporation 6000 Computer was adapted to execute efficiently on the Control Data STAR-100 computer. How the scalar program was adapted for the STAR-100 and why these adaptations yielded an efficient STAR program is described. Program listings of the old scalar version and the vectorized SL/1 version are presented in the appendices. Execution times for the two versions applied to the same system of linear equations, are compared.

User’s Guide for COMBIMAN Programs (COMputerized BIomechanical MAN-Model). Version 4.

DTIC Science & Technology

1981-01-01

103 2.2.23 STATE SWITCH Function (PFK29) 105 2.2.24 RESTART PROGRAM Function (PFK30) 110 2.2.25 END PROGRAM Function (PFK31) il 2.3 EXECUTING THE JOB...108 40 Transformation Equation Developed for Positioning Stomach Link (Set State Switch 72 ON) 109 41 JOB CONTROL CARDS to Execute CBM04. 114 42...154 50b Program CBMAM Survey Member Dimension Definition Cards. 154 51 Example of Survey, or Type 1, Member. 155 52 Job Control Cards to Execute CBMAM

Cooperative Data Sharing: Simple Support for Clusters of SMP Nodes

NASA Technical Reports Server (NTRS)

DiNucci, David C.; Balley, David H. (Technical Monitor)

1997-01-01

Libraries like PVM and MPI send typed messages to allow for heterogeneous cluster computing. Lower-level libraries, such as GAM, provide more efficient access to communication by removing the need to copy messages between the interface and user space in some cases. still lower-level interfaces, such as UNET, get right down to the hardware level to provide maximum performance. However, these are all still interfaces for passing messages from one process to another, and have limited utility in a shared-memory environment, due primarily to the fact that message passing is just another term for copying. This drawback is made more pertinent by today's hybrid architectures (e.g. clusters of SMPs), where it is difficult to know beforehand whether two communicating processes will share memory. As a result, even portable language tools (like HPF compilers) must either map all interprocess communication, into message passing with the accompanying performance degradation in shared memory environments, or they must check each communication at run-time and implement the shared-memory case separately for efficiency. Cooperative Data Sharing (CDS) is a single user-level API which abstracts all communication between processes into the sharing and access coordination of memory regions, in a model which might be described as "distributed shared messages" or "large-grain distributed shared memory". As a result, the user programs to a simple latency-tolerant abstract communication specification which can be mapped efficiently to either a shared-memory or message-passing based run-time system, depending upon the available architecture. Unlike some distributed shared memory interfaces, the user still has complete control over the assignment of data to processors, the forwarding of data to its next likely destination, and the queuing of data until it is needed, so even the relatively high latency present in clusters can be accomodated. CDS does not require special use of an MMU, which can add overhead to some DSM systems, and does not require an SPMD programming model. unlike some message-passing interfaces, CDS allows the user to implement efficient demand-driven applications where processes must "fight" over data, and does not perform copying if processes share memory and do not attempt concurrent writes. CDS also supports heterogeneous computing, dynamic process creation, handlers, and a very simple thread-arbitration mechanism. Additional support for array subsections is currently being considered. The CDS1 API, which forms the kernel of CDS, is built primarily upon only 2 communication primitives, one process initiation primitive, and some data translation (and marshalling) routines, memory allocation routines, and priority control routines. The entire current collection of 28 routines provides enough functionality to implement most (or all) of MPI 1 and 2, which has a much larger interface consisting of hundreds of routines. still, the API is small enough to consider integrating into standard os interfaces for handling inter-process communication in a network-independent way. This approach would also help to solve many of the problems plaguing other higher-level standards such as MPI and PVM which must, in some cases, "play OS" to adequately address progress and process control issues. The CDS2 API, a higher level of interface roughly equivalent in functionality to MPI and to be built entirely upon CDS1, is still being designed. It is intended to add support for the equivalent of communicators, reduction and other collective operations, process topologies, additional support for process creation, and some automatic memory management. CDS2 will not exactly match MPI, because the copy-free semantics of communication from CDS1 will be supported. CDS2 application programs will be free to carefully also use CDS1. CDS1 has been implemented on networks of workstations running unmodified Unix-based operating systems, using UDP/IP and vendor-supplied high- performance locks. Although its inter-node performance is currently unimpressive due to rudimentary implementation technique, it even now outperforms highly-optimized MPI implementation on intra-node communication due to its support for non-copy communication. The similarity of the CDS1 architecture to that of other projects such as UNET and TRAP suggests that the inter-node performance can be increased significantly to surpass MPI or PVM, and it may be possible to migrate some of its functionality to communication controllers.

Superfund: evaluating the impact of executive order 12898.

PubMed

O'Neil, Sandra George

2007-07-01

The U.S. Environmental Protection Agency (EPA) addresses uncontrolled and abandoned hazardous waste sites throughout the country. Sites that are perceived to be a significant threat to both surrounding populations and the environment can be placed on the U.S. EPA Superfund list and qualify for federal cleanup funds. The equitability of the Superfund program has been questioned; the representation of minority and low-income populations in this cleanup program is lower than would be expected. Thus, minorities and low-income populations may not be benefiting proportionately from this environmental cleanup program. In 1994 President Clinton signed Executive Order 12898 requiring that the U.S. EPA and other federal agencies implement environmental justice policies. These policies were to specifically address the disproportionate environmental effects of federal programs and policies on minority and low-income populations. I use event history analysis to evaluate the impact of Executive Order 12898 on the equitability of the Superfund program. Findings suggest that despite environmental justice legislation, Superfund site listings in minority and poor areas are even less likely for sites discovered since the 1994 Executive Order. The results of this study indicate that Executive Order 12898 for environmental justice has not increased the equitability of the Superfund program.

Executive Coaching: Study of the Evolution of the Program at a Top European Business School

ERIC Educational Resources Information Center

Kim, Hyun Jung

2011-01-01

To understand how tensions caused by the multidisciplinary nature of executive coaching are perceived and overcome, this modified ethnographic study was conducted at an executive coaching program and leadership center at a prestigious European business school. This study is built on prolonged discussions on the role of psychology in executive…

5 CFR 2638.701 - Overview.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Executive Agency Ethics Training Programs § 2638.701 Overview. Each agency must have an ethics training program to teach employees about ethics laws and rules and to...

5 CFR 2638.701 - Overview.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Executive Agency Ethics Training Programs § 2638.701 Overview. Each agency must have an ethics training program to teach employees about ethics laws and rules and to...

5 CFR 2638.701 - Overview.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Executive Agency Ethics Training Programs § 2638.701 Overview. Each agency must have an ethics training program to teach employees about ethics laws and rules and to...

5 CFR 2638.701 - Overview.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Executive Agency Ethics Training Programs § 2638.701 Overview. Each agency must have an ethics training program to teach employees about ethics laws and rules and to...

5 CFR 2638.701 - Overview.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Executive Agency Ethics Training Programs § 2638.701 Overview. Each agency must have an ethics training program to teach employees about ethics laws and rules and to...

Practical Application of Model-based Programming and State-based Architecture to Space Missions

NASA Technical Reports Server (NTRS)

Horvath, Gregory; Ingham, Michel; Chung, Seung; Martin, Oliver; Williams, Brian

2006-01-01

A viewgraph presentation to develop models from systems engineers that accomplish mission objectives and manage the health of the system is shown. The topics include: 1) Overview; 2) Motivation; 3) Objective/Vision; 4) Approach; 5) Background: The Mission Data System; 6) Background: State-based Control Architecture System; 7) Background: State Analysis; 8) Overview of State Analysis; 9) Background: MDS Software Frameworks; 10) Background: Model-based Programming; 10) Background: Titan Model-based Executive; 11) Model-based Execution Architecture; 12) Compatibility Analysis of MDS and Titan Architectures; 13) Integrating Model-based Programming and Execution into the Architecture; 14) State Analysis and Modeling; 15) IMU Subsystem State Effects Diagram; 16) Titan Subsystem Model: IMU Health; 17) Integrating Model-based Programming and Execution into the Software IMU; 18) Testing Program; 19) Computationally Tractable State Estimation & Fault Diagnosis; 20) Diagnostic Algorithm Performance; 21) Integration and Test Issues; 22) Demonstrated Benefits; and 23) Next Steps

Academic Executive Programs in Public Administration and Management: Some Variety across Europe

ERIC Educational Resources Information Center

Reichard, Christoph

2017-01-01

Universities and other higher education institutions in Europe offer a vast and increasing number of academic degree programs in the broad field of Public Administration. A subset of these programs is those offering postgraduate degrees to experienced students being already employed by public or private organisations. These executive programs are…

Performance Measurement, Visualization and Modeling of Parallel and Distributed Programs

NASA Technical Reports Server (NTRS)

Yan, Jerry C.; Sarukkai, Sekhar R.; Mehra, Pankaj; Lum, Henry, Jr. (Technical Monitor)

1994-01-01

This paper presents a methodology for debugging the performance of message-passing programs on both tightly coupled and loosely coupled distributed-memory machines. The AIMS (Automated Instrumentation and Monitoring System) toolkit, a suite of software tools for measurement and analysis of performance, is introduced and its application illustrated using several benchmark programs drawn from the field of computational fluid dynamics. AIMS includes (i) Xinstrument, a powerful source-code instrumentor, which supports both Fortran77 and C as well as a number of different message-passing libraries including Intel's NX Thinking Machines' CMMD, and PVM; (ii) Monitor, a library of timestamping and trace -collection routines that run on supercomputers (such as Intel's iPSC/860, Delta, and Paragon and Thinking Machines' CM5) as well as on networks of workstations (including Convex Cluster and SparcStations connected by a LAN); (iii) Visualization Kernel, a trace-animation facility that supports source-code clickback, simultaneous visualization of computation and communication patterns, as well as analysis of data movements; (iv) Statistics Kernel, an advanced profiling facility, that associates a variety of performance data with various syntactic components of a parallel program; (v) Index Kernel, a diagnostic tool that helps pinpoint performance bottlenecks through the use of abstract indices; (vi) Modeling Kernel, a facility for automated modeling of message-passing programs that supports both simulation -based and analytical approaches to performance prediction and scalability analysis; (vii) Intrusion Compensator, a utility for recovering true performance from observed performance by removing the overheads of monitoring and their effects on the communication pattern of the program; and (viii) Compatibility Tools, that convert AIMS-generated traces into formats used by other performance-visualization tools, such as ParaGraph, Pablo, and certain AVS/Explorer modules.

Symbolic Analysis of Concurrent Programs with Polymorphism

NASA Technical Reports Server (NTRS)

Rungta, Neha Shyam

2010-01-01

The current trend of multi-core and multi-processor computing is causing a paradigm shift from inherently sequential to highly concurrent and parallel applications. Certain thread interleavings, data input values, or combinations of both often cause errors in the system. Systematic verification techniques such as explicit state model checking and symbolic execution are extensively used to detect errors in such systems [7, 9]. Explicit state model checking enumerates possible thread schedules and input data values of a program in order to check for errors [3, 9]. To partially mitigate the state space explosion from data input values, symbolic execution techniques substitute data input values with symbolic values [5, 7, 6]. Explicit state model checking and symbolic execution techniques used in conjunction with exhaustive search techniques such as depth-first search are unable to detect errors in medium to large-sized concurrent programs because the number of behaviors caused by data and thread non-determinism is extremely large. We present an overview of abstraction-guided symbolic execution for concurrent programs that detects errors manifested by a combination of thread schedules and data values [8]. The technique generates a set of key program locations relevant in testing the reachability of the target locations. The symbolic execution is then guided along these locations in an attempt to generate a feasible execution path to the error state. This allows the execution to focus in parts of the behavior space more likely to contain an error.

A Study on the Effectiveness of Lockup-Free Caches for a Reduced Instruction Set Computer (RISC) Processor

DTIC Science & Technology

1992-09-01

to acquire or develop effective simulation tools to observe the behavior of a RISC implementation as it executes different types of programs . We choose...Performance Computer performance is measured by the amount of the time required to execute a program . Performance encompasses two types of time, elapsed time...and CPU time. Elapsed time is the time required to execute a program from start to finish. It includes latency of input/output activities such as

Executive Doctoral Programs for Experienced Educational Leaders: A Comparative Analysis

ERIC Educational Resources Information Center

Passaro, Kristin Schomisch

2012-01-01

This qualitative study of four executive doctoral programs for experienced educational leaders examines the relationship between specific program features and learning opportunities for students. I found that the weekend format, cohort model, and professionally grounded curriculum and assessments provided important opportunities for reflective…

Credit WCT. Original 21" x 2A" color negative is housed ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Credit WCT. Original 2-1" x 2-A" color negative is housed in the JPL Photography Laboratory, Pasadena, California. The mixing pot of the 150-gallon (Size 16-PVM) Baker-Perkins vertical mixer appears in its lowered position, exposing the mixer paddles. JPL employees Harold "Andy" Anderson and Ron Wright in protective clothing demonstrate how to scrape mixed propellant from mixer blades (JPL negative JPL10284BC, 27 January 1989) - Jet Propulsion Laboratory Edwards Facility, Mixer, Edwards Air Force Base, Boron, Kern County, CA

Young, Gifted, and Handicapped: Mainstreaming High Potential Handicapped Students into the Executive High School Internships Program.

ERIC Educational Resources Information Center

Hirsch, Sharlene P.

The document describes the Executive High School Internships program which mainstreamed a pilot group of 14 high potential students with orthopedic, hearing, and sight impairments into a project which enabled them to spend a full term, on leave from classes, in nonpaid placements with public and private sector managers and executives, learning how…

Performance enhancement of various real-time image processing techniques via speculative execution

NASA Astrophysics Data System (ADS)

Younis, Mohamed F.; Sinha, Purnendu; Marlowe, Thomas J.; Stoyenko, Alexander D.

1996-03-01

In real-time image processing, an application must satisfy a set of timing constraints while ensuring the semantic correctness of the system. Because of the natural structure of digital data, pure data and task parallelism have been used extensively in real-time image processing to accelerate the handling time of image data. These types of parallelism are based on splitting the execution load performed by a single processor across multiple nodes. However, execution of all parallel threads is mandatory for correctness of the algorithm. On the other hand, speculative execution is an optimistic execution of part(s) of the program based on assumptions on program control flow or variable values. Rollback may be required if the assumptions turn out to be invalid. Speculative execution can enhance average, and sometimes worst-case, execution time. In this paper, we target various image processing techniques to investigate applicability of speculative execution. We identify opportunities for safe and profitable speculative execution in image compression, edge detection, morphological filters, and blob recognition.

A 24-Week Multi-Modality Exercise Program Improves Executive Control in Older Adults with a Self-Reported Cognitive Complaint: Evidence from the Antisaccade Task.

PubMed

Heath, Matthew; Shellington, Erin; Titheridge, Sam; Gill, Dawn P; Petrella, Robert J

2017-01-01

Exercise programs involving aerobic and resistance training (i.e., multiple-modality) have shown promise in improving cognition and executive control in older adults at risk, or experiencing, cognitive decline. It is, however, unclear whether cognitive training within a multiple-modality program elicits an additive benefit to executive/cognitive processes. This is an important question to resolve in order to identify optimal training programs that delay, or ameliorate, executive deficits in persons at risk for further cognitive decline. In the present study, individuals with a self-reported cognitive complaint (SCC) participated in a 24-week multiple-modality (i.e., the M2 group) exercise intervention program. In addition, a separate group of individuals with a SCC completed the same aerobic and resistance training as the M2 group but also completed a cognitive-based stepping task (i.e., multiple-modality, mind-motor intervention: M4 group). Notably, pre- and post-intervention executive control was examined via the antisaccade task (i.e., eye movement mirror-symmetrical to a target). Antisaccades are an ideal tool for the study of individuals with subtle executive deficits because of its hands- and language-free nature and because the task's neural mechanisms are linked to neuropathology in cognitive decline (i.e., prefrontal cortex). Results showed that M2 and M4 group antisaccade reaction times reliably decreased from pre- to post-intervention and the magnitude of the decrease was consistent across groups. Thus, multi-modality exercise training improved executive performance in persons with a SCC independent of mind-motor training. Accordingly, we propose that multiple-modality training provides a sufficient intervention to improve executive control in persons with a SCC.

Using Student Input to Develop a Marketing Strategy for an Executive MBA Program

ERIC Educational Resources Information Center

Geissler, Gary L.

2011-01-01

Despite continued growth in the number of Executive MBA (EMBA) Programs in the U. S. and worldwide, previous research concerning the marketing of EMBA Programs has been very limited. Here, the author investigates ways to successfully market an EMBA Program at a southern U. S. university. Extensive exploratory research was conducted among current…

A Study of the Development of Students' Visualizations of Program State during an Elementary Object-Oriented Programming Course

ERIC Educational Resources Information Center

Sajaniemi, Jorma; Kuittinen, Marja; Tikansalo, Taina

2008-01-01

Students' understanding of object-oriented (OO) program execution was studied by asking students to draw a picture of a program state at a specific moment. Students were given minimal instructions on what to include in their drawings in order to see what they considered to be central concepts and relationships in program execution. Three drawing…

Superfund: Evaluating the Impact of Executive Order 12898

PubMed Central

O’Neil, Sandra George

2007-01-01

Background The U.S. Environmental Protection Agency (EPA) addresses uncontrolled and abandoned hazardous waste sites throughout the country. Sites that are perceived to be a significant threat to both surrounding populations and the environment can be placed on the U.S. EPA Superfund list and qualify for federal cleanup funds. The equitability of the Superfund program has been questioned; the representation of minority and low-income populations in this cleanup program is lower than would be expected. Thus, minorities and low-income populations may not be benefiting proportionately from this environmental cleanup program. In 1994 President Clinton signed Executive Order 12898 requiring that the U.S. EPA and other federal agencies implement environmental justice policies. These policies were to specifically address the disproportionate environmental effects of federal programs and policies on minority and low-income populations. Objective and Methods I use event history analysis to evaluate the impact of Executive Order 12898 on the equitability of the Superfund program. Discussion Findings suggest that despite environmental justice legislation, Superfund site listings in minority and poor areas are even less likely for sites discovered since the 1994 Executive Order. Conclusion The results of this study indicate that Executive Order 12898 for environmental justice has not increased the equitability of the Superfund program. PMID:17637927

Development and Implementation of a Telecommuting Evaluation Framework, and Modeling the Executive Telecommuting Adoption Process

NASA Astrophysics Data System (ADS)

Vora, V. P.; Mahmassani, H. S.

2002-02-01

This work proposes and implements a comprehensive evaluation framework to document the telecommuter, organizational, and societal impacts of telecommuting through telecommuting programs. Evaluation processes and materials within the outlined framework are also proposed and implemented. As the first component of the evaluation process, the executive survey is administered within a public sector agency. The survey data is examined through exploratory analysis and is compared to a previous survey of private sector executives. The ordinal probit, dynamic probit, and dynamic generalized ordinal probit (DGOP) models of telecommuting adoption are calibrated to identify factors which significantly influence executive adoption preferences and to test the robustness of such factors. The public sector DGOP model of executive willingness to support telecommuting under different program scenarios is compared with an equivalent private sector DGOP model. Through the telecommuting program, a case study of telecommuting travel impacts is performed to further substantiate research.

Localized Fault Recovery for Nested Fork-Join Programs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kestor, Gokcen; Krishnamoorthy, Sriram; Ma, Wenjing

Nested fork-join programs scheduled using work stealing can automatically balance load and adapt to changes in the execution environment. In this paper, we design an approach to efficiently recover from faults encountered by these programs. Specifically, we focus on localized recovery of the task space in the presence of fail-stop failures. We present an approach to efficiently track, under work stealing, the relationships between the work executed by various threads. This information is used to identify and schedule the tasks to be re-executed without interfering with normal task execution. The algorithm precisely computes the work lost, incurs minimal re-execution overhead,more » and can recover from an arbitrary number of failures. Experimental evaluation demonstrates low overheads in the absence of failures, recovery overheads on the same order as the lost work, and much lower recovery costs than alternative strategies.« less

Web Program for Development of GUIs for Cluster Computers

NASA Technical Reports Server (NTRS)

Czikmantory, Akos; Cwik, Thomas; Klimeck, Gerhard; Hua, Hook; Oyafuso, Fabiano; Vinyard, Edward

2003-01-01

WIGLAF (a Web Interface Generator and Legacy Application Facade) is a computer program that provides a Web-based, distributed, graphical-user-interface (GUI) framework that can be adapted to any of a broad range of application programs, written in any programming language, that are executed remotely on any cluster computer system. WIGLAF enables the rapid development of a GUI for controlling and monitoring a specific application program running on the cluster and for transferring data to and from the application program. The only prerequisite for the execution of WIGLAF is a Web-browser program on a user's personal computer connected with the cluster via the Internet. WIGLAF has a client/server architecture: The server component is executed on the cluster system, where it controls the application program and serves data to the client component. The client component is an applet that runs in the Web browser. WIGLAF utilizes the Extensible Markup Language to hold all data associated with the application software, Java to enable platform-independent execution on the cluster system and the display of a GUI generator through the browser, and the Java Remote Method Invocation software package to provide simple, effective client/server networking.

Leadership roles, competencies, and education: how prepared are our nurse managers?

PubMed

Kleinman, Carol S

2003-09-01

Although they are responsible for the operation of business units, nurse managers are often less well prepared to manage the business activities than the clinical activities. Perceptions of nurse managers and nurse executives regarding competencies required for nursing management roles and the educational preparation required to attain them were examined. Results indicate the groups are in basic agreement about required competencies, though nurse managers appear less clear about nurse executive role responsibilities. Nurse executives value the acquisition of a master's degree as essential for nurse manager performance, while fewer nurse managers agree. Strategies nurse executives may employ to develop nurse manager business knowledge include traditional undergraduate and graduate degree programs, online programs, certificate programs, continuing education, inservice education offerings, seminars, and mentoring activities.

A direct-execution parallel architecture for the Advanced Continuous Simulation Language (ACSL)

NASA Technical Reports Server (NTRS)

Carroll, Chester C.; Owen, Jeffrey E.

1988-01-01

A direct-execution parallel architecture for the Advanced Continuous Simulation Language (ACSL) is presented which overcomes the traditional disadvantages of simulations executed on a digital computer. The incorporation of parallel processing allows the mapping of simulations into a digital computer to be done in the same inherently parallel manner as they are currently mapped onto an analog computer. The direct-execution format maximizes the efficiency of the executed code since the need for a high level language compiler is eliminated. Resolution is greatly increased over that which is available with an analog computer without the sacrifice in execution speed normally expected with digitial computer simulations. Although this report covers all aspects of the new architecture, key emphasis is placed on the processing element configuration and the microprogramming of the ACLS constructs. The execution times for all ACLS constructs are computed using a model of a processing element based on the AMD 29000 CPU and the AMD 29027 FPU. The increase in execution speed provided by parallel processing is exemplified by comparing the derived execution times of two ACSL programs with the execution times for the same programs executed on a similar sequential architecture.

Model Checking Abstract PLEXIL Programs with SMART

NASA Technical Reports Server (NTRS)

Siminiceanu, Radu I.

2007-01-01

We describe a method to automatically generate discrete-state models of abstract Plan Execution Interchange Language (PLEXIL) programs that can be analyzed using model checking tools. Starting from a high-level description of a PLEXIL program or a family of programs with common characteristics, the generator lays the framework that models the principles of program execution. The concrete parts of the program are not automatically generated, but require the modeler to introduce them by hand. As a case study, we generate models to verify properties of the PLEXIL macro constructs that are introduced as shorthand notation. After an exhaustive analysis, we conclude that the macro definitions obey the intended semantics and behave as expected, but contingently on a few specific requirements on the timing semantics of micro-steps in the concrete executive implementation.

Quality-by-Design (QbD): An integrated process analytical technology (PAT) approach for a dynamic pharmaceutical co-precipitation process characterization and process design space development.

PubMed

Wu, Huiquan; White, Maury; Khan, Mansoor A

2011-02-28

The aim of this work was to develop an integrated process analytical technology (PAT) approach for a dynamic pharmaceutical co-precipitation process characterization and design space development. A dynamic co-precipitation process by gradually introducing water to the ternary system of naproxen-Eudragit L100-alcohol was monitored at real-time in situ via Lasentec FBRM and PVM. 3D map of count-time-chord length revealed three distinguishable process stages: incubation, transition, and steady-state. The effects of high risk process variables (slurry temperature, stirring rate, and water addition rate) on both derived co-precipitation process rates and final chord-length-distribution were evaluated systematically using a 3(3) full factorial design. Critical process variables were identified via ANOVA for both transition and steady state. General linear models (GLM) were then used for parameter estimation for each critical variable. Clear trends about effects of each critical variable during transition and steady state were found by GLM and were interpreted using fundamental process principles and Nyvlt's transfer model. Neural network models were able to link process variables with response variables at transition and steady state with R(2) of 0.88-0.98. PVM images evidenced nucleation and crystal growth. Contour plots illustrated design space via critical process variables' ranges. It demonstrated the utility of integrated PAT approach for QbD development. Published by Elsevier B.V.

Selfconsistent vibrational and free electron kinetics for CO2 dissociation in cold plasmas

NASA Astrophysics Data System (ADS)

Capitelli, Mario

2016-09-01

The activation of CO2 by cold plasmas is receiving new theoretical interest thanks to two European groups. The Bogaerts group developed a global model for the activation of CO2 trying to reproduce the experimental values for DBD and microwave discharges. The approach of Pietanza et al was devoted to understand the dependence of electron energy distribution function (eedf) of pure CO2 on the presence of concentrations of electronically and vibrationally excited states taken as parameter. To understand the importance of the vibrational excitation in the dissociation process Pietanza et al compared an upper limit to the dissociation process from a pure vibrational mechanism (PVM) with the corresponding electron impact dissociation rate, the prevalence of the two models depending on the reduced electric field and on the choice of the electron molecule cross section database. Improvement of the Pietanza et al model is being considered by coupling the time dependent Boltzmann solver with the non equilibrium vibrational kinetics of asymmetric mode and with simplified plasma chemistry kinetics describing the ionization/recombination process and the excitation-deexcitation of a metastable level at 10.5eV. A new PVM mechanism is also considered. Preliminary results, for both discharge and post discharge conditions, emphasize the action of superelastic collisions involving both vibrationally and electronically excited states in affecting the eedf. The new results can be used to plan a road map for future developments of numerical codes for rationalizing existing experimental values, as well as, for indicating new experimental situations.

Plasmid mediated antimicrobial resistance in Ontario isolates of Actinobacillus (Haemophilus) pleuropneumoniae.

PubMed Central

Gilbride, K A; Rosendal, S; Brunton, J L

1989-01-01

The genetic basis of antimicrobial resistance in Ontario isolates of Actinobacillus (Haemophilus) pleuropneumoniae was studied. Two Ontario isolates of A. pleuropneumoniae were found to be resistant to sulfonamides (Su), streptomycin (Sm) and ampicillin (Amp). Resistance to Su and Sm was specified by a 2.3 megadalton (Mdal) plasmid which appeared to be identical to pVM104, which has been described in isolates of A. pleuropneumoniae from South Dakota. Southern hybridization showed that the 2.3 Mdal Su Sm plasmid was highly related to those Hinc II fragments of RSF1010 known to carry the Su Sm genes, but was unrelated to the remainder of this Salmonella resistance plasmid. Resistance to Su and Amp was specified by a 3.5 Mdal plasmid and appeared identical to pVM105 previously reported. The beta-lactamase enzyme had an isoelectric point of approximately 9.0. Southern hybridization showed no relationship to the TEM beta-lactamase. A third isolate of A. pleuropneumoniae was found to be resistant to chloramphenicol (Cm), Su and Sm by virtue of a 3.0 Mdal plasmid which specified a chloramphenicol acetyl transferase. We conclude that resistance to Su, Sm, Amp and Cm is mediated by small plasmids in A. pleuropneumoniae. Although the Su and Sm resistance determinants are highly related to those found in Enterobacteriaceae, the plasmids themselves and the beta-lactamase determinant are different. Images Fig. 1. Fig. 2. Fig. 3. Fig. 4. PMID:2914226

Air Traffic Complexity Measurement Environment (ACME): Software User's Guide

NASA Technical Reports Server (NTRS)

1996-01-01

A user's guide for the Air Traffic Complexity Measurement Environment (ACME) software is presented. The ACME consists of two major components, a complexity analysis tool and user interface. The Complexity Analysis Tool (CAT) analyzes complexity off-line, producing data files which may be examined interactively via the Complexity Data Analysis Tool (CDAT). The Complexity Analysis Tool is composed of three independently executing processes that communicate via PVM (Parallel Virtual Machine) and Unix sockets. The Runtime Data Management and Control process (RUNDMC) extracts flight plan and track information from a SAR input file, and sends the information to GARP (Generate Aircraft Routes Process) and CAT (Complexity Analysis Task). GARP in turn generates aircraft trajectories, which are utilized by CAT to calculate sector complexity. CAT writes flight plan, track and complexity data to an output file, which can be examined interactively. The Complexity Data Analysis Tool (CDAT) provides an interactive graphic environment for examining the complexity data produced by the Complexity Analysis Tool (CAT). CDAT can also play back track data extracted from System Analysis Recording (SAR) tapes. The CDAT user interface consists of a primary window, a controls window, and miscellaneous pop-ups. Aircraft track and position data is displayed in the main viewing area of the primary window. The controls window contains miscellaneous control and display items. Complexity data is displayed in pop-up windows. CDAT plays back sector complexity and aircraft track and position data as a function of time. Controls are provided to start and stop playback, adjust the playback rate, and reposition the display to a specified time.

24 CFR 886.334 - Execution of housing assistance payments contract.

Code of Federal Regulations, 2010 CFR

2010-04-01

... DIRECT LOAN PROGRAM, SECTION 202 SUPPORTIVE HOUSING FOR THE ELDERLY PROGRAM AND SECTION 811 SUPPORTIVE... Market Rent or the exception rent provided in § 886.310 in effect at the time of execution of the...

Post-game analysis: An initial experiment for heuristic-based resource management in concurrent systems

NASA Technical Reports Server (NTRS)

Yan, Jerry C.

1987-01-01

In concurrent systems, a major responsibility of the resource management system is to decide how the application program is to be mapped onto the multi-processor. Instead of using abstract program and machine models, a generate-and-test framework known as 'post-game analysis' that is based on data gathered during program execution is proposed. Each iteration consists of (1) (a simulation of) an execution of the program; (2) analysis of the data gathered; and (3) the proposal of a new mapping that would have a smaller execution time. These heuristics are applied to predict execution time changes in response to small perturbations applied to the current mapping. An initial experiment was carried out using simple strategies on 'pipeline-like' applications. The results obtained from four simple strategies demonstrated that for this kind of application, even simple strategies can produce acceptable speed-up with a small number of iterations.

Building Management Information Systems to Coordinate Citywide Afterschool Programs: A Toolkit for Cities. Executive Summary

ERIC Educational Resources Information Center

Kingsley, Chris

2012-01-01

This executive summary describes highlights from the report, "Building Management Information Systems to Coordinate Citywide Afterschool Programs: A Toolkit for Cities." City-led efforts to build coordinated systems of afterschool programming are an important strategy for improving the health, safety and academic preparedness of children…

Reconfiguration in Robust Distributed Real-Time Systems Based on Global Checkpoints

DTIC Science & Technology

1991-12-01

achieved by utilizing distributed systems in which a single application program executes on multiple processors, connected to a network. The distributed...single application program executes on multiple proces- sors, connected to a network. The distributed nature of such systems make it possible to ...resident at every node. How - ever, the responsibility for execution of a particular function is assigned to only one node in this framework. This function

Lean and Efficient Software: Whole-Program Optimization of Executables

DTIC Science & Technology

2015-09-30

libraries. Many levels of library interfaces—where some libraries are dynamically linked and some are provided in binary form only—significantly limit...software at build time. The opportunity: Our objective in this project is to substantially improve the performance, size, and robustness of binary ...executables by using static and dynamic binary program analysis techniques to perform whole-program optimization directly on compiled programs

Achievement Motivation Training and Executive Advancement

ERIC Educational Resources Information Center

Aronoff, Joel; Litwin, George H.

1971-01-01

Executives who were given a program designed to strengthen their need for achievement were matched with comparable executives chosen to attend the corporation's executive development course during approximately the same period. In a followup study, participants in the motivation training course had performed significantly better than their matched…

Statewide intelligent transportation systems earmark evaluation. Part B, executive summary

DOT National Transportation Integrated Search

2003-11-01

As the recipient of Intelligent Transportation System (ITS) Integration Program funds, the Wisconsin Department of Transportation is required to perform a self-evaluation on each program supported by the funds. This executive summary summarizes the r...

17 CFR 200.16 - Executive Assistant to the Chairman.

Code of Federal Regulations, 2011 CFR

2011-04-01

... ORGANIZATION; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Organization and Program Management General Organization § 200.16 Executive Assistant to the Chairman. The Executive Assistant to the Chairman assists the...

Monitored execution of robot plans produced by STRIPS.

NASA Technical Reports Server (NTRS)

Fikes, R. E.

1972-01-01

We describe PLANEX1, a plan executor for the Stanford Research Institute robot system. The problem-solving program STRIPS creates a plan consisting of a sequence of actions, and PLANEX1 program carries out the plan by executing the actions. PLANEX1 is designed so that it executes only that portion of the plan necessary for completing the task, reexecutes any portion of the plan that has failed to achieve the desired results, and initiates replanning in situations where the plan can no longer be effective in completing the task. The scenario for an example plan execution is given.

MPI_XSTAR: MPI-based Parallelization of the XSTAR Photoionization Program

NASA Astrophysics Data System (ADS)

Danehkar, Ashkbiz; Nowak, Michael A.; Lee, Julia C.; Smith, Randall K.

2018-02-01

We describe a program for the parallel implementation of multiple runs of XSTAR, a photoionization code that is used to predict the physical properties of an ionized gas from its emission and/or absorption lines. The parallelization program, called MPI_XSTAR, has been developed and implemented in the C++ language by using the Message Passing Interface (MPI) protocol, a conventional standard of parallel computing. We have benchmarked parallel multiprocessing executions of XSTAR, using MPI_XSTAR, against a serial execution of XSTAR, in terms of the parallelization speedup and the computing resource efficiency. Our experience indicates that the parallel execution runs significantly faster than the serial execution, however, the efficiency in terms of the computing resource usage decreases with increasing the number of processors used in the parallel computing.

Executive Leadership for Women: Examining the Rhetoric and the Reality

ERIC Educational Resources Information Center

Cocchio, Kathy L.

2009-01-01

This review was prompted by the significant under-representation of women in Canadian corporate executive positions and the University of Alberta's Executive Education and Lifelong Learning department's interest in determining whether a market exists for an executive education program designed specifically for women. I expected that I would find…

Cache Locality Optimization for Recursive Programs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lifflander, Jonathan; Krishnamoorthy, Sriram

We present an approach to optimize the cache locality for recursive programs by dynamically splicing--recursively interleaving--the execution of distinct function invocations. By utilizing data effect annotations, we identify concurrency and data reuse opportunities across function invocations and interleave them to reduce reuse distance. We present algorithms that efficiently track effects in recursive programs, detect interference and dependencies, and interleave execution of function invocations using user-level (non-kernel) lightweight threads. To enable multi-core execution, a program is parallelized using a nested fork/join programming model. Our cache optimization strategy is designed to work in the context of a random work stealing scheduler. Wemore » present an implementation using the MIT Cilk framework that demonstrates significant improvements in sequential and parallel performance, competitive with a state-of-the-art compile-time optimizer for loop programs and a domain- specific optimizer for stencil programs.« less

Varying execution discipline to increase performance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Campbell, P.L.; Maccabe, A.B.

1993-12-22

This research investigates the relationship between execution discipline and performance. The hypothesis has two parts: 1. Different execution disciplines exhibit different performance for different computations, and 2. These differences can be effectively predicted by heuristics. A machine model is developed that can vary its execution discipline. That is, the model can execute a given program using either the control-driven, data-driven or demand-driven execution discipline. This model is referred to as a ``variable-execution-discipline`` machine. The instruction set for the model is the Program Dependence Web (PDW). The first part of the hypothesis will be tested by simulating the execution of themore » machine model on a suite of computations, based on the Livermore Fortran Kernel (LFK) Test (a.k.a. the Livermore Loops), using all three execution disciplines. Heuristics are developed to predict relative performance. These heuristics predict (a) the execution time under each discipline for one iteration of each loop and (b) the number of iterations taken by that loop; then the heuristics use those predictions to develop a prediction for the execution of the entire loop. Similar calculations are performed for branch statements. The second part of the hypothesis will be tested by comparing the results of the simulated execution with the predictions produced by the heuristics. If the hypothesis is supported, then the door is open for the development of machines that can vary execution discipline to increase performance.« less

5 CFR 2638.602 - Annual agency reports.

Code of Federal Regulations, 2010 CFR

2010-01-01

...; (3) A description and evaluation of the agency's program of ethics education, training and counseling... 2638.602 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Executive Branch Agency Reports § 2638.602...

5 CFR 2638.402 - Corrective orders.

Code of Federal Regulations, 2011 CFR

2011-01-01

....402 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Correction of Executive Branch Agency Ethics... agency ethics program is not in full compliance with the requirements set forth in applicable statutes or...

5 CFR 2638.702 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Executive Agency Ethics Training Programs § 2638.702 Definitions... agency in concurrence with the Office of Government Ethics under 5 CFR 2635.105. Employee includes...

5 CFR 2638.702 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Executive Agency Ethics Training Programs § 2638.702 Definitions... agency in concurrence with the Office of Government Ethics under 5 CFR 2635.105. Employee includes...

5 CFR 2638.402 - Corrective orders.

Code of Federal Regulations, 2010 CFR

2010-01-01

....402 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Correction of Executive Branch Agency Ethics... agency ethics program is not in full compliance with the requirements set forth in applicable statutes or...

5 CFR 2638.702 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Executive Agency Ethics Training Programs § 2638.702 Definitions... agency in concurrence with the Office of Government Ethics under 5 CFR 2635.105. Employee includes...

5 CFR 2638.402 - Corrective orders.

Code of Federal Regulations, 2014 CFR

2014-01-01

....402 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Correction of Executive Branch Agency Ethics... agency ethics program is not in full compliance with the requirements set forth in applicable statutes or...

5 CFR 2638.702 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Executive Agency Ethics Training Programs § 2638.702 Definitions... agency in concurrence with the Office of Government Ethics under 5 CFR 2635.105. Employee includes...

5 CFR 2638.402 - Corrective orders.

Code of Federal Regulations, 2012 CFR

2012-01-01

....402 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Correction of Executive Branch Agency Ethics... agency ethics program is not in full compliance with the requirements set forth in applicable statutes or...

5 CFR 2638.402 - Corrective orders.

Code of Federal Regulations, 2013 CFR

2013-01-01

....402 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Correction of Executive Branch Agency Ethics... agency ethics program is not in full compliance with the requirements set forth in applicable statutes or...

Adaptive runtime for a multiprocessing API

DOEpatents

Antao, Samuel F.; Bertolli, Carlo; Eichenberger, Alexandre E.; O'Brien, John K.

2016-11-15

A computer-implemented method includes selecting a runtime for executing a program. The runtime includes a first combination of feature implementations, where each feature implementation implements a feature of an application programming interface (API). Execution of the program is monitored, and the execution uses the runtime. Monitor data is generated based on the monitoring. A second combination of feature implementations are selected, by a computer processor, where the selection is based at least in part on the monitor data. The runtime is modified by activating the second combination of feature implementations to replace the first combination of feature implementations.

Adaptive runtime for a multiprocessing API

DOEpatents

Antao, Samuel F.; Bertolli, Carlo; Eichenberger, Alexandre E.; O'Brien, John K.

2016-10-11

A computer-implemented method includes selecting a runtime for executing a program. The runtime includes a first combination of feature implementations, where each feature implementation implements a feature of an application programming interface (API). Execution of the program is monitored, and the execution uses the runtime. Monitor data is generated based on the monitoring. A second combination of feature implementations are selected, by a computer processor, where the selection is based at least in part on the monitor data. The runtime is modified by activating the second combination of feature implementations to replace the first combination of feature implementations.

Project to Mainstream Gifted Handicapped Students into Selected Models of the Executive High School Internships Program: Evaluation Report.

ERIC Educational Resources Information Center

Baken, Joan W.; Benner, Susan M.

As a supplement to the standard in-school high school curriculum, the Executive High School Internship Program provides experiential learning opportunities for gifted high school students. The program focuses on management-level field placements through which participants learn to make decisions, interact with the world-of-work, and assume…

An Evaluation of the Right to Read Inexpensive Book Distribution Program. Executive Summary.

ERIC Educational Resources Information Center

General Research Corp., McLean, VA.

This document is an executive summary of a study examining the Inexpensive Book Distribution Program (IBDP), a federally funded and sponsored program operated by Reading is Fundamental (RIF). Sections of the report provide the following information: (1) methodology and procedures for conducting the study, (2) a brief description of RIF national…

Mandarins and Lemons--The Executive Investment in Program Evaluation.

ERIC Educational Resources Information Center

MacDonald, Barry

The author contends that within executive government, which already has all the information it needs to make decisions, program evaluation is seen as a symbolic rather than a substantive enterprise. If it is assumed that program evaluation is an end of policy, not a means, the reasons for government investment in evaluation include: (1) no choice;…

36th ATLANTA EXECUTIVE SEMINAR

DTIC Science & Technology

2011-04-04

Elimination of Chemical Weapons Program. In addition, he is responsible for appointing, managing, and evaluating program executive officers as well as...little can be spared.” The National Commission of Fiscal responsibility, The Moment, December 2010 Slide 14 Congressional Weapon System Concerns ...Acquisition and Technology (A&T), and the Defense Acquisition Board on acquisition/procurement strategies for all major weapon systems programs

An Overview of the Runtime Verification Tool Java PathExplorer

NASA Technical Reports Server (NTRS)

Havelund, Klaus; Rosu, Grigore; Clancy, Daniel (Technical Monitor)

2002-01-01

We present an overview of the Java PathExplorer runtime verification tool, in short referred to as JPAX. JPAX can monitor the execution of a Java program and check that it conforms with a set of user provided properties formulated in temporal logic. JPAX can in addition analyze the program for concurrency errors such as deadlocks and data races. The concurrency analysis requires no user provided specification. The tool facilitates automated instrumentation of a program's bytecode, which when executed will emit an event stream, the execution trace, to an observer. The observer dispatches the incoming event stream to a set of observer processes, each performing a specialized analysis, such as the temporal logic verification, the deadlock analysis and the data race analysis. Temporal logic specifications can be formulated by the user in the Maude rewriting logic, where Maude is a high-speed rewriting system for equational logic, but here extended with executable temporal logic. The Maude rewriting engine is then activated as an event driven monitoring process. Alternatively, temporal specifications can be translated into efficient automata, which check the event stream. JPAX can be used during program testing to gain increased information about program executions, and can potentially furthermore be applied during operation to survey safety critical systems.

Symbolic Execution Over Native x86

DTIC Science & Technology

2012-06-01

Disassembly to a Hello World Program Packed with the Ulti- mate Packer for eXecutables (UPX) (Taken from IDA Pro) . . . . . . . 7 Figure 2.3 A Simple Hello...Program Packed with the Ultimate Packer for eXecutables (UPX) (Taken from IDA Pro) operation details. However, the design of an IL language leads to...The Unofficial Guide to the World’s Most Popular Disas- sembler. No Starch Press, 2008. [13] Hex-Rays, “Interactive disassembler (ida) pro.” [Online

Helicopter In-Flight Monitoring System Second Generation (HIMS II).

DTIC Science & Technology

1983-08-01

acquisition cycle. B. Computer Chassis CPU (DEC LSI-II/2) -- Executes instructions contained in the memory. 32K memory (DEC MSVII-DD) --Contains program...when the operator executes command #2, 3, or 5 (display data). New cartridges can be inserted as required for truly unlimited, continuous data...is called bootstrapping. The software, which is stored on a tape cartridge, is loaded into memory by execution of a small program stored in read-only

Statistical Symbolic Execution with Informed Sampling

NASA Technical Reports Server (NTRS)

Filieri, Antonio; Pasareanu, Corina S.; Visser, Willem; Geldenhuys, Jaco

2014-01-01

Symbolic execution techniques have been proposed recently for the probabilistic analysis of programs. These techniques seek to quantify the likelihood of reaching program events of interest, e.g., assert violations. They have many promising applications but have scalability issues due to high computational demand. To address this challenge, we propose a statistical symbolic execution technique that performs Monte Carlo sampling of the symbolic program paths and uses the obtained information for Bayesian estimation and hypothesis testing with respect to the probability of reaching the target events. To speed up the convergence of the statistical analysis, we propose Informed Sampling, an iterative symbolic execution that first explores the paths that have high statistical significance, prunes them from the state space and guides the execution towards less likely paths. The technique combines Bayesian estimation with a partial exact analysis for the pruned paths leading to provably improved convergence of the statistical analysis. We have implemented statistical symbolic execution with in- formed sampling in the Symbolic PathFinder tool. We show experimentally that the informed sampling obtains more precise results and converges faster than a purely statistical analysis and may also be more efficient than an exact symbolic analysis. When the latter does not terminate symbolic execution with informed sampling can give meaningful results under the same time and memory limits.

Lazy evaluation of FP programs: A data-flow approach

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wei, Y.H.; Gaudiot, J.L.

1988-12-31

This paper presents a lazy evaluation system for the list-based functional language, Backus` FP in data-driven environment. A superset language of FP, called DFP (Demand-driven FP), is introduced. FP eager programs are transformed into DFP lazy programs which contain the notions of demands. The data-driven execution of DFP programs has the same effects of lazy evaluation. DFP lazy programs have the property of always evaluating a sufficient and necessary result. The infinite sequence generator is used to demonstrate the eager-lazy program transformation and the execution of the lazy programs.

Parallel Event Analysis Under Unix

NASA Astrophysics Data System (ADS)

Looney, S.; Nilsson, B. S.; Oest, T.; Pettersson, T.; Ranjard, F.; Thibonnier, J.-P.

The ALEPH experiment at LEP, the CERN CN division and Digital Equipment Corp. have, in a joint project, developed a parallel event analysis system. The parallel physics code is identical to ALEPH's standard analysis code, ALPHA, only the organisation of input/output is changed. The user may switch between sequential and parallel processing by simply changing one input "card". The initial implementation runs on an 8-node DEC 3000/400 farm, using the PVM software, and exhibits a near-perfect speed-up linearity, reducing the turn-around time by a factor of 8.

Scalable and reusable emulator for evaluating the performance of SS7 networks

NASA Astrophysics Data System (ADS)

Lazar, Aurel A.; Tseng, Kent H.; Lim, Koon Seng; Choe, Winston

1994-04-01

A scalable and reusable emulator was designed and implemented for studying the behavior of SS7 networks. The emulator design was largely based on public domain software. It was developed on top of an environment supported by PVM, the Parallel Virtual Machine, and managed by OSIMIS-the OSI Management Information Service platform. The emulator runs on top of a commercially available ATM LAN interconnecting engineering workstations. As a case study for evaluating the emulator, the behavior of the Singapore National SS7 Network under fault and unbalanced loading conditions was investigated.

Operate A Chemical Surety Program And Studies Supporting The Medical Chemical Defense Research Program

DTIC Science & Technology

2010-05-01

23 Task Execution Plan 34 – Temperature Testing of Pyridostigmine Bromide (PB) .......... 23 KEY RESEARCH ACCOMPLISHMENTS...29, 2010. Staff was assembled and materials have been ordered. Task Execution Plan (TEP) 0034 – Temperature Testing of Pyridostigmine Bromide

5 CFR 2638.401 - In general.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Correction of Executive Branch Agency Ethics Programs § 2638.401 In general. The Director of the Office of Government Ethics has authority under subsections 402(b)(9...

5 CFR 2638.401 - In general.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Correction of Executive Branch Agency Ethics Programs § 2638.401 In general. The Director of the Office of Government Ethics has authority under subsections 402(b)(9...

78 FR 4421 - National Institute on Drug Abuse; Notice of Closed Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-22

...: National Institutes of Health, Neuroscience Center, 6001 Executive Boulevard, Rockville, MD 20852... contract proposals. Place: National Institutes of Health, Neuroscience Center, 6001 Executive Boulevard... Federal Domestic Assistance Program Nos.: 93.279, Drug Abuse and Addiction Research Programs, National...

5 CFR 2638.401 - In general.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Correction of Executive Branch Agency Ethics Programs § 2638.401 In general. The Director of the Office of Government Ethics has authority under subsections 402(b)(9...

5 CFR 2638.401 - In general.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Correction of Executive Branch Agency Ethics Programs § 2638.401 In general. The Director of the Office of Government Ethics has authority under subsections 402(b)(9...

5 CFR 2638.401 - In general.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Correction of Executive Branch Agency Ethics Programs § 2638.401 In general. The Director of the Office of Government Ethics has authority under subsections 402(b)(9...

Space station executive summary

NASA Technical Reports Server (NTRS)

1972-01-01

An executive summary of the modular space station study is presented. The subjects discussed are: (1) design characteristics, (2) experiment program, (3) operations, (4) program description, and (5) research implications. The modular space station is considered a candidate payload for the low cost shuttle transportation system.

SPOT Program

NASA Technical Reports Server (NTRS)

Smith, Jason T.; Welsh, Sam J.; Farinetti, Antonio L.; Wegner, Tim; Blakeslee, James; Deboeck, Toni F.; Dyer, Daniel; Corley, Bryan M.; Ollivierre, Jarmaine; Kramer, Leonard;

Functional behavioral analysis and social scripting for the older patient with schizophrenia: a staff development program.

PubMed

Markwick, Laura; Smith, Charlene; Mick, Diane

2014-11-01

Executive functioning is the ability to plan, strategize, organize, and focus on details. Impaired executive functioning plays a significant role in behavior disturbances. Lack of inhibition, impaired abstract reasoning, thought perseverance, rigidity in routine, and lack of insight disrupt social skills and daily life. Autism and schizophrenia present some similar behaviors, including impaired executive functioning, often resulting in pharmacological management as many healthcare professionals receive limited training in executive functioning. Non-pharmacological tools used in autism for behavior management include functional behavioral analysis and social scripting, which help to identify causes of behavior and teach more appropriate behavioral responses. Described here is an educational program for healthcare workers in a long-term care skilled nursing facility, to help them understand the basis for behaviors in individuals with impaired executive function, to use these same tools for behavioral modification techniques, and to help patients learn more appropriate social skills. Program evaluation suggested the educational program was successful in increasing the staff's knowledge and comfort level in addressing the behavioral issues that arise with this population and staff also reported less use of medication as first-line treatment for behavioral issues.

A pilot study of an online cognitive rehabilitation program for executive function skills in children with cancer-related brain injury

PubMed Central

Kesler, Shelli R.; Lacayo, Norman J.; Jo, Booil

2011-01-01

Primary objectives Children with a history of cancer are at increased risk for cognitive impairments, particularly in executive and memory domains. Traditional, in-person cognitive rehabilitation strategies may be unavailable and/or impractical for many of these children given difficulties related to resources and health status. The feasibility and efficacy of implementing a computerized, home-based cognitive rehabilitation curriculum designed to improve executive function skills was examined in these children. Methods A one-arm open trial pilot study of an original executive function cognitive rehabilitation curriculum was conducted with 23 paediatric cancer survivors aged 7–19. Results Compliance with the cognitive rehabilitation program was 83%, similar to that of many traditional programs. Following the cognitive intervention, participants showed significantly increased processing speed, cognitive flexibility, verbal and visual declarative memory scores as well as significantly increased pre-frontal cortex activation compared to baseline. Conclusions These results suggest that a program of computerized cognitive exercises can be successfully implemented at home in young children with cancer. These exercises may be effective for improving executive and memory skills in this group, with concurrent changes in neurobiologic status. PMID:21142826

A Rewriting-Based Approach to Trace Analysis

NASA Technical Reports Server (NTRS)

Havelund, Klaus; Rosu, Grigore; Clancy, Daniel (Technical Monitor)

2002-01-01

We present a rewriting-based algorithm for efficiently evaluating future time Linear Temporal Logic (LTL) formulae on finite execution traces online. While the standard models of LTL are infinite traces, finite traces appear naturally when testing and/or monitoring red applications that only run for limited time periods. The presented algorithm is implemented in the Maude executable specification language and essentially consists of a set of equations establishing an executable semantics of LTL using a simple formula transforming approach. The algorithm is further improved to build automata on-the-fly from formulae, using memoization. The result is a very efficient and small Maude program that can be used to monitor program executions. We furthermore present an alternative algorithm for synthesizing probably minimal observer finite state machines (or automata) from LTL formulae, which can be used to analyze execution traces without the need for a rewriting system, and can hence be used by observers written in conventional programming languages. The presented work is part of an ambitious runtime verification and monitoring project at NASA Ames, called PATHEXPLORER, and demonstrates that rewriting can be a tractable and attractive means for experimenting and implementing program monitoring logics.

Traditional and Online Learning in Executive Education: How Both Will Survive and Thrive

ERIC Educational Resources Information Center

Stanton, Wilbur W.; Stanton, Angela D'Auria

2017-01-01

An important component of corporate training is executive education. A sample of 90 open enrollment executive education programs in the areas of management development and leadership was reviewed to better understand the structure of the offerings. In today's marketplace, the majority of executive education offerings are of the traditional…

Primer for the Transportable Applications Executive

NASA Technical Reports Server (NTRS)

Carlson, P. A.; Emmanuelli, C. A.; Harris, E. L.; Perkins, D. C.

1984-01-01

The Transportable Applications Executive (TAE), an interactive multipurpose executive that provides commonly required functions for scientific analysis systems, is discussed. The concept of an executive is discussed and the various components of TAE are presented. These include on-line help information, the use of menus or commands to access analysis programs, and TAE command procedures.

The Hedwig van Ameringen Executive Leadership in Academic MedicineRTM Program for Women: An Explanatory Study Regarding Its Development and Persistence

ERIC Educational Resources Information Center

Mensel, Ruth

2010-01-01

This study was designed to determine which factors contributed to the development and persistence of a women's leadership development program in higher education. The "Hedwig van Ameringen" Executive Leadership in Academic Medicine[R] "Program for Women" was the basis for this single-case study. To speculate about ELAM's development and…

Preparing High School Students for College: An Exploratory Study of College Readiness Partnership Programs in Texas. Executive Summary

ERIC Educational Resources Information Center

Barnett, Elisabeth A.; Corrin, William; Nakanishi, Aki; Bork, Rachel Hare; Mitchell, Claire; Sepanik, Susan

2012-01-01

This paper presents an executive summary of a study that examines a number of college readiness partnership programs operating in Texas and identifies their features, targeted students, and intended outcomes. It also examines the partnerships that created these programs. The findings presented here are based on a search and analysis of the…

Joint Operational Medicine Information Systems (JOMIS)

DTIC Science & Technology

2016-03-01

Component is Program Executive Office (PEO) Department of Defense (DoD) Healthcare Management Systems (DHMS) for Defense Health Agency (DHA). Responsible...AT&L)) and the Program Executive Office (PEO) Defense Healthcare Management Systems (DHMS). ​Operational medicine is the application of routine and...acquired by the DoD Healthcare Management System Modernization (DHMSM) program for Health Care Delivery (HCD) capabilities. JOMIS future release(s

Method and apparatus for collaborative use of application program

DOEpatents

Dean, Craig D.

1994-01-01

Method and apparatus permitting the collaborative use of a computer application program simultaneously by multiple users at different stations. The method is useful with communication protocols having client/server control structures. The method of the invention requires only a sole executing copy of the application program and a sole executing copy of software comprising the invention. Users may collaboratively use a set of application programs by invoking for each desired application program one copy of software comprising the invention.

AIDPRF/PRFAID user's manual

NASA Technical Reports Server (NTRS)

Buck, C. H.

1975-01-01

The program documentation for the PRF ARTWORK/AIDS conversion program, which serves as the interface between the outputs of the PRF ARTWORK and AIDS programs, was presented. The document has a two-fold purpose, the first of which is a description of the software design including flowcharts of the design at the functional level. The second purpose is to provide the user with a detailed description of the input parameters and formats necessary to execute the program and a description of the output produced when the program is executed.

DISSPLA plotting routines for the G-189A EC/LS computer program

NASA Technical Reports Server (NTRS)

Simpson, C. D.

1982-01-01

Data from a G-189A execution is formatted and plotted. The plotting may be done at the time of execution of the program. DISSPLA plot packages are used. The user has the choice of FR80 or TEKTRONIX output.

Adult Learning in Executive Development Programs

ERIC Educational Resources Information Center

Wuestewald, Todd

2016-01-01

Executive development programs (EDPs) have undergone significant change since their introduction in the early 20th century. As an adjunct or alternative to traditional education, EDPs are considered an efficient means of imparting critical, functional, and social-behavior skills to current and future organizational leaders. Consequently, such…

76 FR 24893 - National Institute on Drug Abuse; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-03

... applications. Place: National Institutes of Health, Neuroscience Center, 6001 Executive Boulevard, Conference... developments in the drug abuse field. Place: National Institutes of Health, Neuroscience Center, 6001 Executive... Federal Domestic Assistance Program Nos.: 93.279, Drug Abuse and Addiction Research Programs, National...

Sensorimotor speech disorders in Parkinson's disease: Programming and execution deficits.

PubMed

Ortiz, Karin Zazo; Brabo, Natalia Casagrande; Minett, Thais Soares C

2016-01-01

Dysfunction in the basal ganglia circuits is a determining factor in the physiopathology of the classic signs of Parkinson's disease (PD) and hypokinetic dysarthria is commonly related to PD. Regarding speech disorders associated with PD, the latest four-level framework of speech complicates the traditional view of dysarthria as a motor execution disorder. Based on findings that dysfunctions in basal ganglia can cause speech disorders, and on the premise that the speech deficits seen in PD are not related to an execution motor disorder alone but also to a disorder at the motor programming level, the main objective of this study was to investigate the presence of sensorimotor disorders of programming (besides the execution disorders previously described) in PD patients. A cross-sectional study was conducted in a sample of 60 adults matched for gender, age and education: 30 adult patients diagnosed with idiopathic PD (PDG) and 30 healthy adults (CG). All types of articulation errors were reanalyzed to investigate the nature of these errors. Interjections, hesitations and repetitions of words or sentences (during discourse) were considered typical disfluencies; blocking, episodes of palilalia (words or syllables) were analyzed as atypical disfluencies. We analysed features including successive self-initiated trial, phoneme distortions, self-correction, repetition of sounds and syllables, prolonged movement transitions, additions or omissions of sounds and syllables, in order to identify programming and/or execution failures. Orofacial agility was also investigated. The PDG had worse performance on all sensorimotor speech tasks. All PD patients had hypokinetic dysarthria. The clinical characteristics found suggest both execution and programming sensorimotor speech disorders in PD patients.

Pick_sw: a program for interactive picking of S-wave data, version 2.00

USGS Publications Warehouse

Ellefsen, Karl J.

2002-01-01

Program pick_sw is used to interactively pick travel times from S-wave data. It is assumed that the data are collected using 2 shots of opposite polarity at each shot location. The traces must be in either the SEG-2 format or the SU format. The program is written in the IDL and C programming languages, and the program is executed under the Windows operating system. (The program may also execute under other operating systems like UNIX if the C language functions are re-compiled).

Monitoring Java Programs with Java PathExplorer

NASA Technical Reports Server (NTRS)

Havelund, Klaus; Rosu, Grigore; Clancy, Daniel (Technical Monitor)

2001-01-01

We present recent work on the development Java PathExplorer (JPAX), a tool for monitoring the execution of Java programs. JPAX can be used during program testing to gain increased information about program executions, and can potentially furthermore be applied during operation to survey safety critical systems. The tool facilitates automated instrumentation of a program's late code which will then omit events to an observer during its execution. The observer checks the events against user provided high level requirement specifications, for example temporal logic formulae, and against lower level error detection procedures, for example concurrency related such as deadlock and data race algorithms. High level requirement specifications together with their underlying logics are defined in the Maude rewriting logic, and then can either be directly checked using the Maude rewriting engine, or be first translated to efficient data structures and then checked in Java.

Reliability techniques for computer executive programs

NASA Technical Reports Server (NTRS)

1972-01-01

Computer techniques for increasing the stability and reliability of executive and supervisory systems were studied. Program segmentation characteristics are discussed along with a validation system which is designed to retain the natural top down outlook in coding. An analysis of redundancy techniques and roll back procedures is included.

A Program Management Framework for Facilities Managers

ERIC Educational Resources Information Center

King, Dan

2012-01-01

The challenge faced by senior facility leaders is not how to execute a single project, but rather, how to successfully execute a large program consisting of hundreds of projects. Senior facilities officers at universities, school districts, hospitals, airports, and other organizations with extensive facility inventories, typically manage project…

Method for resource control in parallel environments using program organization and run-time support

NASA Technical Reports Server (NTRS)

Ekanadham, Kattamuri (Inventor); Moreira, Jose Eduardo (Inventor); Naik, Vijay Krishnarao (Inventor)

2001-01-01

A system and method for dynamic scheduling and allocation of resources to parallel applications during the course of their execution. By establishing well-defined interactions between an executing job and the parallel system, the system and method support dynamic reconfiguration of processor partitions, dynamic distribution and redistribution of data, communication among cooperating applications, and various other monitoring actions. The interactions occur only at specific points in the execution of the program where the aforementioned operations can be performed efficiently.

Method for resource control in parallel environments using program organization and run-time support

NASA Technical Reports Server (NTRS)

Ekanadham, Kattamuri (Inventor); Moreira, Jose Eduardo (Inventor); Naik, Vijay Krishnarao (Inventor)

1999-01-01

A system and method for dynamic scheduling and allocation of resources to parallel applications during the course of their execution. By establishing well-defined interactions between an executing job and the parallel system, the system and method support dynamic reconfiguration of processor partitions, dynamic distribution and redistribution of data, communication among cooperating applications, and various other monitoring actions. The interactions occur only at specific points in the execution of the program where the aforementioned operations can be performed efficiently.

Symbolic PathFinder: Symbolic Execution of Java Bytecode

NASA Technical Reports Server (NTRS)

Pasareanu, Corina S.; Rungta, Neha

2010-01-01

Symbolic Pathfinder (SPF) combines symbolic execution with model checking and constraint solving for automated test case generation and error detection in Java programs with unspecified inputs. In this tool, programs are executed on symbolic inputs representing multiple concrete inputs. Values of variables are represented as constraints generated from the analysis of Java bytecode. The constraints are solved using off-the shelf solvers to generate test inputs guaranteed to achieve complex coverage criteria. SPF has been used successfully at NASA, in academia, and in industry.

Development and content validity of the CENA Program for Educational Training on the Neuropsychology of Learning, with an emphasis on executive functions and attention.

PubMed

Pureza, Janice R; Fonseca, Rochele P

2017-01-01

The importance of executive functions (EF) in childhood development, and their role as indicators of health, well-being, professional and academic success have been demonstrated by several studies in the literature. FE are cognitive processes that aim to control and manage behavior to achieve specific goal and included skills planning, inhibition, cognitive flexibility, (executive) attention and the central executive component of working memory (WM). In the context of education, the EF are crucial for continued learning and efficient academic performance due to their involvement in several components of the educational process. The aim of this article was to describe the development and content validity of the CENA Program for Educational Training on the Neuropsychology of Learning, with an emphasis on executive functions and attention. The study involved seven specialists (four responsible for evaluating the program, and three involved in brainstorming), and was carried out in three stages:Background research: neuropsychology and education;Program development - author brainstorming andEvaluation by expert judges The goals, language and methods. CENA Program were considered adequate, attesting to its content validity as a school-based neuropsychological intervention. Teacher training in school neuropsychology may be an important area for future investment and contribute to academic achievement and student development in the Brazilian education system.

Development and content validity of the CENA Program for Educational Training on the Neuropsychology of Learning, with an emphasis on executive functions and attention

PubMed Central

Pureza, Janice R.; Fonseca, Rochele P.

2017-01-01

Introduction The importance of executive functions (EF) in childhood development, and their role as indicators of health, well-being, professional and academic success have been demonstrated by several studies in the literature. FE are cognitive processes that aim to control and manage behavior to achieve specific goal and included skills planning, inhibition, cognitive flexibility, (executive) attention and the central executive component of working memory (WM). In the context of education, the EF are crucial for continued learning and efficient academic performance due to their involvement in several components of the educational process. Objective The aim of this article was to describe the development and content validity of the CENA Program for Educational Training on the Neuropsychology of Learning, with an emphasis on executive functions and attention. Methods The study involved seven specialists (four responsible for evaluating the program, and three involved in brainstorming), and was carried out in three stages: Background research: neuropsychology and education; Program development - author brainstorming and Evaluation by expert judges The goals, language and methods. Results CENA Program were considered adequate, attesting to its content validity as a school-based neuropsychological intervention. Conclusion Teacher training in school neuropsychology may be an important area for future investment and contribute to academic achievement and student development in the Brazilian education system. PMID:29213497

A Public Service-Dominant Logic for the Executive Education of Public Managers

ERIC Educational Resources Information Center

Hiedemann, Alexander M.; Nasi, Greta; Saporito, Raffaella

2017-01-01

Building on the concept of Public Service-Dominant Logic (PSDL), this article aims to apply the public service-dominant logic to executive education. We argue that fit-for-purpose and effective executive master programs for public managers (EMPA) need to be designed from a public service perspective. Framing executive education as a service…

SCORE/ACE Counselor Handbook. Service Corps of Retired Executives. Active Corps of Executives.

ERIC Educational Resources Information Center

Landsverk, Arvel; And Others

This counselor handbook is intended to help Service Corps of Retired Executives/Active Corps of Executives (SCORE/ACE) counselors to plan and conduct counseling services more effectively. Included in the introductory section are an overview of the SCORE/ACE counseling program, a discussion of what the counselor does, directions for completing…

An Evaluation Study of an Executive Master of Business Administration (EMBA) Program in an Urban City: Examining the Transfer of Knowledge and Leadership Practices

ERIC Educational Resources Information Center

Choi, Hye Lim

2011-01-01

This study examined the effectiveness of the Executive Master of Business Administration (EMBA) degree program in terms of transfer of knowledge and leadership practices. Based on a review of literature related to adult learning theories, EMBA programs, the importance of evaluation practices, and leadership practices, this study was designed to…

Creating and Implementing an Offshore Graduate Program: A Case Study of Leadership and Development of the Global Executive MBA Program

ERIC Educational Resources Information Center

Herrera, Marisa L.

2013-01-01

This study applies the literature on leadership framing to the globalization of higher education to understand the development of the Global Executive MBA program at a large university. The purpose of the study was to provide administrators, educators and university leaders an understanding as to how to respond to globalization and, secondly, to…

32 CFR 1803.2 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... FOR MANDATORY DECLASSIFICATION REVIEW OF CLASSIFIED INFORMATION PURSUANT TO SECTION 3.6 OF EXECUTIVE... Coordinator who serves as the NACIC manager of the information review and release program instituted under the mandatory declassification review provisions of Executive Order 12958; Federal agency means any executive...

B cells are not essential for Lactobacillus-mediated protection against lethal pneumovirus infection*

PubMed Central

Percopo, Caroline M.; Dyer, Kimberly D.; Garcia-Crespo, Katia E.; Gabryszewski, Stanislaw J.; Shaffer, Arthur L.; Domachowske, Joseph B.; Rosenberg, Helene F.

2014-01-01

We have shown previously that priming of respiratory mucosa with live Lactobacillus species promotes robust and prolonged survival from an otherwise lethal infection with pneumonia virus of mice (PVM), a property known as heterologous immunity. Lactobacillus-priming results in a moderate reduction in virus recovery and a dramatic reduction in virus-induced proinflammatory cytokine production; the precise mechanisms underlying these findings remain to be elucidated. As B cells have been shown to promote heterologous immunity against respiratory virus pathogens under similar conditions, here we explore the role of B cells in Lactobacillus-mediated protection against acute pneumovirus infection. We found that Lactobacillus-primed mice feature elevated levels of airway immunoglobulins IgG, IgA and IgM and lung tissues with dense, B cell (B220+) enriched peribronchial and perivascular infiltrates with germinal centers consistent with descriptions of bronchus-associated lymphoid tissue. No B cells were detected in lung tissue of Lactobacillus-primed B-cell deficient μMT mice or Jh mice, and Lactobacillus-primed μMT mice had no characteristic infiltrates or airway immunoglobulins. Nonetheless, we observed diminished virus recovery and profound suppression of virus-induced proinflammatory cytokines CCL2, IFN-gamma, and CXCL10 in both wild-type and Lactobacillus-primed μMT mice. Furthermore, L. plantarum-primed, B-cell deficient μMT and Jh mice were fully protected from an otherwise lethal PVM infection, as were their respective wild-types. We conclude that B cells are dispensable for Lactobacillus-mediated heterologous immunity and were not crucial for promoting survival in response to an otherwise lethal pneumovirus infection. PMID:24748495

Distributed multitasking ITS with PVM

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fan, W.C.; Halbleib, J.A. Sr.

1995-12-31

Advances in computer hardware and communication software have made it possible to perform parallel-processing computing on a collection of desktop workstations. For many applications, multitasking on a cluster of high-performance workstations has achieved performance comparable to or better than that on a traditional supercomputer. From the point of view of cost-effectiveness, it also allows users to exploit available but unused computational resources and thus achieve a higher performance-to-cost ratio. Monte Carlo calculations are inherently parallelizable because the individual particle trajectories can be generated independently with minimum need for interprocessor communication. Furthermore, the number of particle histories that can be generatedmore » in a given amount of wall-clock time is nearly proportional to the number of processors in the cluster. This is an important fact because the inherent statistical uncertainty in any Monte Carlo result decreases as the number of histories increases. For these reasons, researchers have expended considerable effort to take advantage of different parallel architectures for a variety of Monte Carlo radiation transport codes, often with excellent results. The initial interest in this work was sparked by the multitasking capability of the MCNP code on a cluster of workstations using the Parallel Virtual Machine (PVM) software. On a 16-machine IBM RS/6000 cluster, it has been demonstrated that MCNP runs ten times as fast as on a single-processor CRAY YMP. In this paper, we summarize the implementation of a similar multitasking capability for the coupled electronphoton transport code system, the Integrated TIGER Series (ITS), and the evaluation of two load-balancing schemes for homogeneous and heterogeneous networks.« less

Distributed multitasking ITS with PVM

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fan, W.C.; Halbleib, J.A. Sr.

1995-02-01

Advances of computer hardware and communication software have made it possible to perform parallel-processing computing on a collection of desktop workstations. For many applications, multitasking on a cluster of high-performance workstations has achieved performance comparable or better than that on a traditional supercomputer. From the point of view of cost-effectiveness, it also allows users to exploit available but unused computational resources, and thus achieve a higher performance-to-cost ratio. Monte Carlo calculations are inherently parallelizable because the individual particle trajectories can be generated independently with minimum need for interprocessor communication. Furthermore, the number of particle histories that can be generated inmore » a given amount of wall-clock time is nearly proportional to the number of processors in the cluster. This is an important fact because the inherent statistical uncertainty in any Monte Carlo result decreases as the number of histories increases. For these reasons, researchers have expended considerable effort to take advantage of different parallel architectures for a variety of Monte Carlo radiation transport codes, often with excellent results. The initial interest in this work was sparked by the multitasking capability of MCNP on a cluster of workstations using the Parallel Virtual Machine (PVM) software. On a 16-machine IBM RS/6000 cluster, it has been demonstrated that MCNP runs ten times as fast as on a single-processor CRAY YMP. In this paper, we summarize the implementation of a similar multitasking capability for the coupled electron/photon transport code system, the Integrated TIGER Series (ITS), and the evaluation of two load balancing schemes for homogeneous and heterogeneous networks.« less

Concurrent simulation of a parallel jaw end effector

NASA Technical Reports Server (NTRS)

Bynum, Bill

1985-01-01

A system of programs developed to aid in the design and development of the command/response protocol between a parallel jaw end effector and the strategic planner program controlling it are presented. The system executes concurrently with the LISP controlling program to generate a graphical image of the end effector that moves in approximately real time in response to commands sent from the controlling program. Concurrent execution of the simulation program is useful for revealing flaws in the communication command structure arising from the asynchronous nature of the message traffic between the end effector and the strategic planner. Software simulation helps to minimize the number of hardware changes necessary to the microprocessor driving the end effector because of changes in the communication protocol. The simulation of other actuator devices can be easily incorporated into the system of programs by using the underlying support that was developed for the concurrent execution of the simulation process and the communication between it and the controlling program.

75 FR 64393 - Approval of Noise Compatibility Program for Chicago Executive Airport, Prospect Heights and...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-19

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Approval of Noise Compatibility... the noise compatibility program (NCP) submitted by the Chicago Executive Airport Board of Directors... Noise Abatement Act, herein referred to as ``the Act'') and 14 CFR part 150. On March 1, 2010, the FAA...

76 FR 4027 - Farm and Ranch Lands Protection Program

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-24

... with Executive Order 12866, NRCS conducted an economic analysis of the potential impacts associated with this program. A summary of the economic analysis can be found at the end of the regulatory... section 1244(g) of the 1985 Act. Economic Analysis--Executive Summary The FRPP is an important tool...

75 FR 30043 - Medicare Program; Meeting of the Advisory Panel on Medicare Education

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-28

... [Medicare Advantage] in order to promote an active, informed selection among such options.'' The Panel is... Program; Yanira Cruz, PhD, President and Chief Executive Officer, National Hispanic Council on Aging... Health; Sandy Markwood, Chief Executive Officer, National Association of Area Agencies on Aging; David W...

7 CFR 1430.221 - Estates, trusts, and minors.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 10 2011-01-01 2011-01-01 false Estates, trusts, and minors. 1430.221 Section 1430... Program § 1430.221 Estates, trusts, and minors. (a) Program documents executed by producers legally... authority to execute such documents. (b) A minor who is otherwise eligible for assistance under this part...

Support from Chief Executives to Sponsored Programs Administration at Baccalaureate Universities in the United States

ERIC Educational Resources Information Center

Hamilton, Zoya

2012-01-01

This research study examined support to sponsored programs administrators (SPAs, or research administrators) at baccalaureate universities from their chief executives. Support to SPAs strengthens the shared purpose of the university, enabling SPAs to serve as effective organizational representatives in business transactions pertaining to grants…

Reading Recovery Executive Summary, 1984 to 1998.

ERIC Educational Resources Information Center

Reading Recovery Council of North America, Columbus, OH.

This Executive Summary provides information and details about Reading Recovery, an early intervention program for young readers who are experiencing difficulty in their first year of reading instruction. The summary first explains that Reading Recovery is a one-to-one tutoring program designed to serve the lowest achieving readers in which…

Support for Debugging Automatically Parallelized Programs

NASA Technical Reports Server (NTRS)

Jost, Gabriele; Hood, Robert; Biegel, Bryan (Technical Monitor)

2001-01-01

We describe a system that simplifies the process of debugging programs produced by computer-aided parallelization tools. The system uses relative debugging techniques to compare serial and parallel executions in order to show where the computations begin to differ. If the original serial code is correct, errors due to parallelization will be isolated by the comparison. One of the primary goals of the system is to minimize the effort required of the user. To that end, the debugging system uses information produced by the parallelization tool to drive the comparison process. In particular the debugging system relies on the parallelization tool to provide information about where variables may have been modified and how arrays are distributed across multiple processes. User effort is also reduced through the use of dynamic instrumentation. This allows us to modify the program execution without changing the way the user builds the executable. The use of dynamic instrumentation also permits us to compare the executions in a fine-grained fashion and only involve the debugger when a difference has been detected. This reduces the overhead of executing instrumentation.

Relative Debugging of Automatically Parallelized Programs

NASA Technical Reports Server (NTRS)

Jost, Gabriele; Hood, Robert; Biegel, Bryan (Technical Monitor)

2002-01-01

We describe a system that simplifies the process of debugging programs produced by computer-aided parallelization tools. The system uses relative debugging techniques to compare serial and parallel executions in order to show where the computations begin to differ. If the original serial code is correct, errors due to parallelization will be isolated by the comparison. One of the primary goals of the system is to minimize the effort required of the user. To that end, the debugging system uses information produced by the parallelization tool to drive the comparison process. In particular, the debugging system relies on the parallelization tool to provide information about where variables may have been modified and how arrays are distributed across multiple processes. User effort is also reduced through the use of dynamic instrumentation. This allows us to modify, the program execution with out changing the way the user builds the executable. The use of dynamic instrumentation also permits us to compare the executions in a fine-grained fashion and only involve the debugger when a difference has been detected. This reduces the overhead of executing instrumentation.

40 CFR 68.155 - Executive summary.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 15 2011-07-01 2011-07-01 false Executive summary. 68.155 Section 68.155 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CHEMICAL ACCIDENT PREVENTION PROVISIONS Risk Management Plan § 68.155 Executive summary. The owner or...

40 CFR 68.155 - Executive summary.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 15 2010-07-01 2010-07-01 false Executive summary. 68.155 Section 68.155 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CHEMICAL ACCIDENT PREVENTION PROVISIONS Risk Management Plan § 68.155 Executive summary. The owner or...

ATLAS, an integrated structural analysis and design system. Volume 3: User's manual, input and execution data

NASA Technical Reports Server (NTRS)

Dreisbach, R. L. (Editor)

1979-01-01

The input data and execution control statements for the ATLAS integrated structural analysis and design system are described. It is operational on the Control Data Corporation (CDC) 6600/CYBER computers in a batch mode or in a time-shared mode via interactive graphic or text terminals. ATLAS is a modular system of computer codes with common executive and data base management components. The system provides an extensive set of general-purpose technical programs with analytical capabilities including stiffness, stress, loads, mass, substructuring, strength design, unsteady aerodynamics, vibration, and flutter analyses. The sequence and mode of execution of selected program modules are controlled via a common user-oriented language.

Optimizing Interactive Development of Data-Intensive Applications

PubMed Central

Interlandi, Matteo; Tetali, Sai Deep; Gulzar, Muhammad Ali; Noor, Joseph; Condie, Tyson; Kim, Miryung; Millstein, Todd

2017-01-01

Modern Data-Intensive Scalable Computing (DISC) systems are designed to process data through batch jobs that execute programs (e.g., queries) compiled from a high-level language. These programs are often developed interactively by posing ad-hoc queries over the base data until a desired result is generated. We observe that there can be significant overlap in the structure of these queries used to derive the final program. Yet, each successive execution of a slightly modified query is performed anew, which can significantly increase the development cycle. Vega is an Apache Spark framework that we have implemented for optimizing a series of similar Spark programs, likely originating from a development or exploratory data analysis session. Spark developers (e.g., data scientists) can leverage Vega to significantly reduce the amount of time it takes to re-execute a modified Spark program, reducing the overall time to market for their Big Data applications. PMID:28405637

Processing Device for High-Speed Execution of an Xrisc Computer Program

NASA Technical Reports Server (NTRS)

Ng, Tak-Kwong (Inventor); Mills, Carl S. (Inventor)

2016-01-01

A processing device for high-speed execution of a computer program is provided. A memory module may store one or more computer programs. A sequencer may select one of the computer programs and controls execution of the selected program. A register module may store intermediate values associated with a current calculation set, a set of output values associated with a previous calculation set, and a set of input values associated with a subsequent calculation set. An external interface may receive the set of input values from a computing device and provides the set of output values to the computing device. A computation interface may provide a set of operands for computation during processing of the current calculation set. The set of input values are loaded into the register and the set of output values are unloaded from the register in parallel with processing of the current calculation set.

Impacts of a prekindergarten program on children's mathematics, language, literacy, executive function, and emotional skills.

PubMed

Weiland, Christina; Yoshikawa, Hirokazu

2013-01-01

Publicly funded prekindergarten programs have achieved small-to-large impacts on children's cognitive outcomes. The current study examined the impact of a prekindergarten program that implemented a coaching system and consistent literacy, language, and mathematics curricula on these and other nontargeted, essential components of school readiness, such as executive functioning. Participants included 2,018 four and five-year-old children. Findings indicated that the program had moderate-to-large impacts on children's language, literacy, numeracy and mathematics skills, and small impacts on children's executive functioning and a measure of emotion recognition. Some impacts were considerably larger for some subgroups. For urban public school districts, results inform important programmatic decisions. For policy makers, results confirm that prekindergarten programs can improve educationally vital outcomes for children in meaningful, important ways. © 2013 The Authors. Child Development © 2013 Society for Research in Child Development, Inc.

Attending to America: Personal Assistance for Independent Living. A Survey of Attendant Service Programs in the United States for People of All Ages with Disabilities. Executive Summary.

ERIC Educational Resources Information Center

Litvak, Simi; And Others

This executive summary reviews results of a survey of 154 publicly-funded programs providing personal assistance services to disabled individuals. Introductory chapters identify the need for a national personal assistance program and policy, the concept of personal assistance and attendant services, the potential user population, and U.S. sources…

Developing leadership talent: a statewide nurse leader mentorship program.

PubMed

Rich, Mary; Kempin, Bettyann; Loughlin, Mary Jo; Vitale, Tracy R; Wurmser, Theresa; Thrall, Terese Hudson

2015-02-01

Nurse leaders continue to seek support programs essential for advancement to senior roles. Providing such support presents a challenge for the future of nursing in the state of New Jersey and on a national level. This article discusses the creation of a mentorship program by the Organization of Nurse Executives of New Jersey (ONE NJ). In recognition of the program, which has contributed to the advancement of New Jersey nursing leadership, the ONE NJ received the 2014 American Organization of Nurse Executives Chapter Achievement Award.

Sensorimotor speech disorders in Parkinson's disease: Programming and execution deficits

PubMed Central

Ortiz, Karin Zazo; Brabo, Natalia Casagrande; Minett, Thais Soares C.

2016-01-01

ABSTRACT Introduction: Dysfunction in the basal ganglia circuits is a determining factor in the physiopathology of the classic signs of Parkinson's disease (PD) and hypokinetic dysarthria is commonly related to PD. Regarding speech disorders associated with PD, the latest four-level framework of speech complicates the traditional view of dysarthria as a motor execution disorder. Based on findings that dysfunctions in basal ganglia can cause speech disorders, and on the premise that the speech deficits seen in PD are not related to an execution motor disorder alone but also to a disorder at the motor programming level, the main objective of this study was to investigate the presence of sensorimotor disorders of programming (besides the execution disorders previously described) in PD patients. Methods: A cross-sectional study was conducted in a sample of 60 adults matched for gender, age and education: 30 adult patients diagnosed with idiopathic PD (PDG) and 30 healthy adults (CG). All types of articulation errors were reanalyzed to investigate the nature of these errors. Interjections, hesitations and repetitions of words or sentences (during discourse) were considered typical disfluencies; blocking, episodes of palilalia (words or syllables) were analyzed as atypical disfluencies. We analysed features including successive self-initiated trial, phoneme distortions, self-correction, repetition of sounds and syllables, prolonged movement transitions, additions or omissions of sounds and syllables, in order to identify programming and/or execution failures. Orofacial agility was also investigated. Results: The PDG had worse performance on all sensorimotor speech tasks. All PD patients had hypokinetic dysarthria. Conclusion: The clinical characteristics found suggest both execution and programming sensorimotor speech disorders in PD patients. PMID:29213457

Execution of a participatory supportive return to work program within the Dutch social security sector: a qualitative evaluation of stakeholders' perceptions.

PubMed

Lammerts, Lieke; Schaafsma, Frederieke G; van Mechelen, Willem; Anema, Johannes R

2016-04-14

A process evaluation of a participatory supportive return to work program, aimed at workers without a (permanent) employment contract who are sick-listed due to a common mental disorder, revealed that this program was executed less successfully than similar programs evaluated in earlier studies. The program consisted of a participatory approach, integrated care and direct placement in competitive employment. Aim of this study was to get a better understanding of the execution of the program by evaluating stakeholders' perceptions. In the absence of an employer, the program was applied by the Dutch Social Security Agency, in collaboration with vocational rehabilitation agencies. Together with the sick-listed workers, these were the main stakeholders. Our research questions involved stakeholders' perceptions of the function(s) of the program, and their perceptions of barriers and facilitators for a successful execution of the program within the Dutch social security sector. Semi-structured interviews were held with five sick-listed workers, eight professionals of the Social Security Agency, and two case managers of vocational rehabilitation agencies. Interview topics were related to experiences with different components of the program. Selection of respondents was based on purposive sampling and continued until data saturation was reached. Content analysis was applied to identify patterns in the data. Two researchers developed a coding system, based on predefined topics and themes emerging from the data. Although perceived functions of some components of the program were as intended, all stakeholders stressed that the program often had not resulted in return to work. Perceived barriers for a successful execution were related to a poor collaboration between the Dutch Social Security Agency, vocational rehabilitation agencies and healthcare providers, the type of experienced (health) problems, time constraints, and limited job opportunities. For future implementation of the program, it will be important to consider how a better integration of services by the Dutch Social Security Agency, vocational rehabilitation agencies and the mental healthcare sector can be improved in order to address treatment and vocational needs simultaneously, and to better match the sick-listed worker with the limited opportunities in the Dutch labor market. NTR3563.

76 FR 59418 - Wildland Fire Executive Council Meeting Schedule

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-26

... DEPARTMENT OF THE INTERIOR Office of the Secretary Wildland Fire Executive Council Meeting... Interior, Office of the Secretary, Wildland Fire Executive Council (WFEC) will meet as indicated below... wildland fire policy and to provide leadership, direction, and program oversight in support of the Wildland...

76 FR 28445 - Wildland Fire Executive Council Meeting Schedule

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-17

... DEPARTMENT OF THE INTERIOR Office of the Secretary Wildland Fire Executive Council Meeting... Interior, Office of the Secretary, Wildland Fire Executive Council (WFEC) will meet as indicated below...-level wildland fire policy and to provide leadership, direction, and program oversight in support of the...

77 FR 63326 - Wildland Fire Executive Council Meeting Schedule

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-16

... DEPARTMENT OF THE INTERIOR Office of the Secretary Wildland Fire Executive Council Meeting... Interior, Office of the Secretary, Wildland Fire Executive Council (WFEC) will meet as indicated below...-level wildland fire policy and to provide leadership, direction, and program oversight in support of the...

76 FR 15332 - Wildland Fire Executive Council Meeting Schedule

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-21

... DEPARTMENT OF THE INTERIOR Office of the Secretary Wildland Fire Executive Council Meeting... Interior, Office of the Secretary, Wildland Fire Executive Council (WFEC) will meet as indicated below...-level wildland fire policy and to provide leadership, direction, and program oversight in support of the...

Executive High School Internships

ERIC Educational Resources Information Center

Hirsch, Sharlene Pearlman

1974-01-01

The Executive High School Internships Program enables juniors and seniors to take a one-semester sabbatical from their studies to serve as special assistants to executives in government, business, non-profit organizations, and civic organizations. They perform a variety of duties, earning full academic credit for their participation. (AG)

7 CFR 656.2 - Archeological and historical laws and Executive orders applicable to NRCS-assisted programs.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 6 2011-01-01 2011-01-01 false Archeological and historical laws and Executive orders applicable to NRCS-assisted programs. 656.2 Section 656.2 Agriculture Regulations of the Department of Agriculture (Continued) NATURAL RESOURCES CONSERVATION SERVICE, DEPARTMENT OF AGRICULTURE SUPPORT ACTIVITIES...

7 CFR 656.2 - Archeological and historical laws and Executive orders applicable to NRCS-assisted programs.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 6 2012-01-01 2012-01-01 false Archeological and historical laws and Executive orders applicable to NRCS-assisted programs. 656.2 Section 656.2 Agriculture Regulations of the Department of Agriculture (Continued) NATURAL RESOURCES CONSERVATION SERVICE, DEPARTMENT OF AGRICULTURE SUPPORT ACTIVITIES...

7 CFR 656.2 - Archeological and historical laws and Executive orders applicable to NRCS-assisted programs.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 6 2013-01-01 2013-01-01 false Archeological and historical laws and Executive orders applicable to NRCS-assisted programs. 656.2 Section 656.2 Agriculture Regulations of the Department of Agriculture (Continued) NATURAL RESOURCES CONSERVATION SERVICE, DEPARTMENT OF AGRICULTURE SUPPORT ACTIVITIES...

1993 at a Glance: Executive Summaries of Reports from the Office of Research and Evaluation.

ERIC Educational Resources Information Center

Austin Independent School District, TX. Office of Research and Evaluation.

This compilation contains executive summaries of 13 program evaluations conducted by the Office of Research and Evaluation of the Austin Independent School District (AISD) (Texas), as well as short summary reports on 3 programs. The following summaries are included: (1) "1991-92 Dropout Report"; (2) "Faculty/Staff Recruitment…

Arab Spring Impact on Executive Education in Egypt

ERIC Educational Resources Information Center

Wafa, Dina

2015-01-01

Purpose: The purpose of this paper is to study the impact of the Arab Spring on public administration programs in Egypt, with a special focus on executive education programs. Design/Methodology/Approach: The study draws on stakeholder analysis, and uses both primary and secondary data. Findings: The author describes the impact of the Arab Spring…

Students Training for Academic Readiness (STAR): Year Three Evaluation Report. Executive Summary

ERIC Educational Resources Information Center

Texas Center for Educational Research, 2010

2010-01-01

This executive summary presents findings from the Year 3 evaluation of Texas' state-level Gaining Early Awareness and Readiness for Undergraduate Programs, or GEAR UP, grant. GEAR UP grant requirements include an evaluation component designed to assess program effectiveness and to measure progress toward project goals. To this end, the evaluation…

10 CFR 611.105 - Agreement.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 4 2014-01-01 2014-01-01 false Agreement. 611.105 Section 611.105 Energy DEPARTMENT OF... Direct Loan Program § 611.105 Agreement. (a) Only an Agreement executed by a duly authorized DOE... paid to DOE relating to the section 136 loan program. (d) Prior to the execution by DOE of an Agreement...

10 CFR 611.105 - Agreement.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 4 2012-01-01 2012-01-01 false Agreement. 611.105 Section 611.105 Energy DEPARTMENT OF... Direct Loan Program § 611.105 Agreement. (a) Only an Agreement executed by a duly authorized DOE... paid to DOE relating to the section 136 loan program. (d) Prior to the execution by DOE of an Agreement...

10 CFR 611.105 - Agreement.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Agreement. 611.105 Section 611.105 Energy DEPARTMENT OF... Direct Loan Program § 611.105 Agreement. (a) Only an Agreement executed by a duly authorized DOE... paid to DOE relating to the section 136 loan program. (d) Prior to the execution by DOE of an Agreement...

10 CFR 611.105 - Agreement.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Agreement. 611.105 Section 611.105 Energy DEPARTMENT OF... Direct Loan Program § 611.105 Agreement. (a) Only an Agreement executed by a duly authorized DOE... paid to DOE relating to the section 136 loan program. (d) Prior to the execution by DOE of an Agreement...

10 CFR 611.105 - Agreement.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 4 2013-01-01 2013-01-01 false Agreement. 611.105 Section 611.105 Energy DEPARTMENT OF... Direct Loan Program § 611.105 Agreement. (a) Only an Agreement executed by a duly authorized DOE... paid to DOE relating to the section 136 loan program. (d) Prior to the execution by DOE of an Agreement...

Developing Enlightened Leaders for Industry and Community: Executive Education and Service-Learning

ERIC Educational Resources Information Center

Rhee, Kenneth S.; Sigler, Tracey Honeycutt

2010-01-01

What does it take to develop enlightened leaders who can transform their organizations and communities? The quest to develop enlightened leaders who are self-aware, learning centered, adaptable, interpersonally competent, and team oriented is a challenge faced by many management programs. The Master of Science program in Executive Leadership and…

An Exploratory Study of the Curricular Integration of Ethics in Executive MBA Programs

ERIC Educational Resources Information Center

Franco, Jaime M.

2011-01-01

An Exploratory Study of the Curricular Integration of Ethics in Executive MBA Programs News headlines of corporate scandals have unleashed a contentious debate of whether or not graduate management education has contributed to corporate collapses and the resultant financial crisis. In particular, questions abound as to the willingness of…

29 CFR 1960.6 - Designation of agency safety and health officials.

Code of Federal Regulations, 2010 CFR

2010-07-01

... safety and health policy and program to carry out the provisions of section 19 of the Act, Executive... implementation of the agency policy and program as required by section 19 of the Act, Executive Order 12196, and... safety and health staff, equipment, materials, and training required to ensure implementation of an...

Model for mapping settlements

DOEpatents

Vatsavai, Ranga Raju; Graesser, Jordan B.; Bhaduri, Budhendra L.

2016-07-05

A programmable media includes a graphical processing unit in communication with a memory element. The graphical processing unit is configured to detect one or more settlement regions from a high resolution remote sensed image based on the execution of programming code. The graphical processing unit identifies one or more settlements through the execution of the programming code that executes a multi-instance learning algorithm that models portions of the high resolution remote sensed image. The identification is based on spectral bands transmitted by a satellite and on selected designations of the image patches.

High Velocity Jet Noise Source Location and Reduction. Task 2 Supplement. Computer Program for Calculating the Aeroacoustic Characteristics of Jets form Nozzles of Arbitrary Shape.

DTIC Science & Technology

1978-05-01

controls and executes the jet plume flow field compu- tation. After each axial slice has been evaluated, the MAIN program calls subroutine SLICE to...input data; otherwise the execution is halted. 4.3.2 ARCCOS(X) This is a function subroutine which computes the principal value of the arc cosine of the... execution time available. Each successive case requires a title card (80 - character label in columns 1 - 80), followed by the INPUT NAMELIST. The data from

Implications of DOD Funds Execution Policy for Acquisition Program Management

DTIC Science & Technology

2014-08-01

I N S T I T U T E F O R D E F E N S E A N A L Y S E S IDA Paper P-5164 August 2014 Implications of DOD Funds Execution Policy for Acquisition...One of the goals of sound financial management practice is that the DOD spends the money that Congress appropriates for national defense in a timely...require execution of funds for any particular program to take place later than planned. That situation creates a natural conflict between two

Literacy in the Workplace: The Executive Perspective. A Qualitative Research Study.

ERIC Educational Resources Information Center

Omega Group, Inc., Haverford, PA.

Twenty-eight in-depth interviews were conducted with top executives in Philadelphia to discover issues and concerns about committing organizational resources over time to workplace literacy programs. Participants represented major organizations and institutions, both manufacturing and service. The executives reported that the manifestations of…

Artemis: Integrating Scientific Data on the Grid (Preprint)

DTIC Science & Technology

2004-07-01

Theseus execution engine [Barish and Knoblock 03] to efficiently execute the generated datalog program. The Theseus execution engine has a wide...variety of operations to query databases, web sources, and web services. Theseus also contains a wide variety of relational operations, such as...selection, union, or projection. Furthermore, Theseus optimizes the execution of an integration plan by querying several data sources in parallel and

Report on Activities and Programs for Countering Proliferation and NBC Terrorism. Volume 1, Executive Summary, Addendum to 2011 Report

DTIC Science & Technology

2013-06-01

Executive Branch report on research , development, and acquisition (RDA) programs to Combat Weapons of Mass Destruction (WMD). Other interagency committees...characterize, secure, disable , and/or destroy a state or non-state actor’s WMD programs and related capabilities in hostile or uncertain environments. Threat...special operations, and security operations to defend against conventionally and unconventionally delivered WMD. WMD Consequence Management. Actions

Exact and Approximate Probabilistic Symbolic Execution

NASA Technical Reports Server (NTRS)

Luckow, Kasper; Pasareanu, Corina S.; Dwyer, Matthew B.; Filieri, Antonio; Visser, Willem

2014-01-01

Probabilistic software analysis seeks to quantify the likelihood of reaching a target event under uncertain environments. Recent approaches compute probabilities of execution paths using symbolic execution, but do not support nondeterminism. Nondeterminism arises naturally when no suitable probabilistic model can capture a program behavior, e.g., for multithreading or distributed systems. In this work, we propose a technique, based on symbolic execution, to synthesize schedulers that resolve nondeterminism to maximize the probability of reaching a target event. To scale to large systems, we also introduce approximate algorithms to search for good schedulers, speeding up established random sampling and reinforcement learning results through the quantification of path probabilities based on symbolic execution. We implemented the techniques in Symbolic PathFinder and evaluated them on nondeterministic Java programs. We show that our algorithms significantly improve upon a state-of- the-art statistical model checking algorithm, originally developed for Markov Decision Processes.

Symbolic Execution Enhanced System Testing

NASA Technical Reports Server (NTRS)

Davies, Misty D.; Pasareanu, Corina S.; Raman, Vishwanath

2012-01-01

We describe a testing technique that uses information computed by symbolic execution of a program unit to guide the generation of inputs to the system containing the unit, in such a way that the unit's, and hence the system's, coverage is increased. The symbolic execution computes unit constraints at run-time, along program paths obtained by system simulations. We use machine learning techniques treatment learning and function fitting to approximate the system input constraints that will lead to the satisfaction of the unit constraints. Execution of system input predictions either uncovers new code regions in the unit under analysis or provides information that can be used to improve the approximation. We have implemented the technique and we have demonstrated its effectiveness on several examples, including one from the aerospace domain.

The Inaugural Report of the Global Maritime and Air Communities of Interest Intelligence Enterprises

DTIC Science & Technology

2009-11-01

iii Executive Summary...and recommending changes to authorities, responsibilities, programs, resources, and operations of the enterprise members. iv Executive Summary...furthered that goal by developing a vision and executing a strategy to rapidly create an integrated maritime and air intelligence capability that

Repositioning Your EMBA Program and Reinventing Your Brand: A Case Study Analysis

ERIC Educational Resources Information Center

Petit, Francis

2009-01-01

The purpose of this research is to illustrate how Fordham University, the Jesuit University of New York, repositioned its Executive MBA Program and reinvented its brand, over a ten year period. More specifically, this research will analyze the current state of the Executive MBA market and will discuss the best practices and frameworks implemented…

75 FR 14287 - Energy Conservation Program: Test Procedures for Fluorescent Lamp Ballasts

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-24

... Government Appropriations Act, 2001 J. Executive Order 13211 K. Executive Order 12630 L. Section 32 of the... and Background Title III of the Energy Policy and Conservation Act (42 U.S.C. 6291 et seq.; EPCA or... (42 U.S.C. 6291-6309) establishes the ``Energy Conservation Program for Consumer Products Other Than...

Follow-Up Study of Former Students of the Executive Secretarial Program. Volume XVI, No. 2.

ERIC Educational Resources Information Center

Jirak, Mary Ann; Lucas, John A.

A study was conducted at Illinois' William Rainey Harper College (WRHC) to assess the current employment experiences of students who had been enrolled in the college's Executive Secretarial Program. The study population consisted of all 232 students who completed SEC-237 (Secretarial Seminar and Internship) between fall 1976 and spring 1986, and…

A 30-Minute Physical Education Program Improves Students' Executive Attention

ERIC Educational Resources Information Center

Kubesch, Sabine; Walk, Laura; Spitzer, Manfred; Kammer, Thomas; Lainburg, Alyona; Heim, Rudiger; Hille, Katrin

2009-01-01

Physical activity is not only beneficial to physical health but also to cognitive functions. In particular, executive functions that are closely related to learning achievement can be improved by acute and recurring physical activity. We examined the effects of a single 30-min physical education program in contrast to a 5-min movement break on…

FWP executive summaries: basic energy sciences materials sciences and engineering program (SNL/NM).

DOE Office of Scientific and Technical Information (OSTI.GOV)

Samara, George A.; Simmons, Jerry A.

2006-07-01

This report presents an Executive Summary of the various elements of the Materials Sciences and Engineering Program which is funded by the Division of Materials Sciences and Engineering, Office of Basic Energy Sciences, U.S. Department of Energy at Sandia National Laboratories, New Mexico. A general programmatic overview is also presented.

Symbolic Dynamics, Flower Automata and Infinite Traces

NASA Astrophysics Data System (ADS)

Foryś, Wit; Oprocha, Piotr; Bakalarski, Slawomir

Considering a finite alphabet as a set of allowed instructions, we can identify finite words with basic actions or programs. Hence infinite paths on a flower automaton can represent order in which these programs are executed and a flower shift related with it represents list of instructions to be executed at some mid-point of the computation.

Hawaii energy strategy: Executive summary, October 1995

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

This is an executive summary to a report on the Hawaii Energy Strategy Program. The topics of the report include the a description of the program including an overview, objectives, policy statement and purpose and objectives; energy strategy policy development; energy strategy projects; current energy situation; modeling Hawaii`s energy future; energy forecasts; reducing energy demand; scenario assessment, and recommendations.

7 CFR 1404.4 - Execution of assignment form.

Code of Federal Regulations, 2013 CFR

2013-01-01

... assignment form. (a)(1) The assignment of any FSA or CCC payment must be made by the execution of Form CCC-36 or Forms CCC-251 and CCC-252. Form CCC-36 is applicable to payments made under programs administered... applicable to any other program which is administered by a county ASC committee. Forms CCC-251 and 252 are...

7 CFR 1404.4 - Execution of assignment form.

Code of Federal Regulations, 2011 CFR

2011-01-01

... assignment form. (a)(1) The assignment of any FSA or CCC payment must be made by the execution of Form CCC-36 or Forms CCC-251 and CCC-252. Form CCC-36 is applicable to payments made under programs administered... applicable to any other program which is administered by a county ASC committee. Forms CCC-251 and 252 are...

7 CFR 1404.4 - Execution of assignment form.

Code of Federal Regulations, 2014 CFR

2014-01-01

... assignment form. (a)(1) The assignment of any FSA or CCC payment must be made by the execution of Form CCC-36 or Forms CCC-251 and CCC-252. Form CCC-36 is applicable to payments made under programs administered... applicable to any other program which is administered by a county ASC committee. Forms CCC-251 and 252 are...

7 CFR 1404.4 - Execution of assignment form.

Code of Federal Regulations, 2010 CFR

2010-01-01

... assignment form. (a)(1) The assignment of any FSA or CCC payment must be made by the execution of Form CCC-36 or Forms CCC-251 and CCC-252. Form CCC-36 is applicable to payments made under programs administered... applicable to any other program which is administered by a county ASC committee. Forms CCC-251 and 252 are...

7 CFR 1404.4 - Execution of assignment form.

Code of Federal Regulations, 2012 CFR

2012-01-01

... assignment form. (a)(1) The assignment of any FSA or CCC payment must be made by the execution of Form CCC-36 or Forms CCC-251 and CCC-252. Form CCC-36 is applicable to payments made under programs administered... applicable to any other program which is administered by a county ASC committee. Forms CCC-251 and 252 are...

Levinson's Dream Theory and Its Relevance in an Academic Executive Mentoring Program: An Exploratory Study of Executive Mentors' Practice and Individuation

ERIC Educational Resources Information Center

Scherer, Douglas Martin

2010-01-01

The purpose of this study was to explore the relevance that executive mentors' Dream journeys had for their mentoring practices. Dream journeys are the visions of where young adults see themselves in the future, and how they integrate themselves into the adult world over time. It was anticipated that a better understanding of executive mentors'…

Texas hospital chief executive officers evaluate content areas in health administration education.

PubMed

Harkins, L T; Herkimer, A G

1995-01-01

Health care executives are confronted by a working environment that is increasingly difficult to manage. Skyrocketing health care costs, with shrinking reimbursement, threaten the existence of hospitals. A successful hospital chief executive officer (CEO) is one who can effectively manage his/her hospital in spite of industry challenges and problems. Graduate programs in health services administration must be designed to meet the needs of future health care executives. Many times, educators are criticized for not addressing "real world" issues within the curricular structure. The present study was conducted to gather information from executives who are the experts on what to expect in the health care industry regarding the appropriateness of curricular topics. Results indicate that practicing CEOs believe those curricular areas which focus on financial planning, budgeting, medical-legal issues, and strategic planning are more important than those that deal with international health care, epidemiology, or research methods. The information gathered in this study may be useful as a guide for educators, to evaluate and revise existing graduate programs in health care administration. Data presented here may also be used to assist in long-range planning for new health administration programs.

Cloudgene: A graphical execution platform for MapReduce programs on private and public clouds

PubMed Central

2012-01-01

Background The MapReduce framework enables a scalable processing and analyzing of large datasets by distributing the computational load on connected computer nodes, referred to as a cluster. In Bioinformatics, MapReduce has already been adopted to various case scenarios such as mapping next generation sequencing data to a reference genome, finding SNPs from short read data or matching strings in genotype files. Nevertheless, tasks like installing and maintaining MapReduce on a cluster system, importing data into its distributed file system or executing MapReduce programs require advanced knowledge in computer science and could thus prevent scientists from usage of currently available and useful software solutions. Results Here we present Cloudgene, a freely available platform to improve the usability of MapReduce programs in Bioinformatics by providing a graphical user interface for the execution, the import and export of data and the reproducibility of workflows on in-house (private clouds) and rented clusters (public clouds). The aim of Cloudgene is to build a standardized graphical execution environment for currently available and future MapReduce programs, which can all be integrated by using its plug-in interface. Since Cloudgene can be executed on private clusters, sensitive datasets can be kept in house at all time and data transfer times are therefore minimized. Conclusions Our results show that MapReduce programs can be integrated into Cloudgene with little effort and without adding any computational overhead to existing programs. This platform gives developers the opportunity to focus on the actual implementation task and provides scientists a platform with the aim to hide the complexity of MapReduce. In addition to MapReduce programs, Cloudgene can also be used to launch predefined systems (e.g. Cloud BioLinux, RStudio) in public clouds. Currently, five different bioinformatic programs using MapReduce and two systems are integrated and have been successfully deployed. Cloudgene is freely available at http://cloudgene.uibk.ac.at. PMID:22888776

Neuro-Cognitive Intervention for Working Memory: Preliminary Results and Future Directions.

PubMed

Bree, Kathleen D; Beljan, Paul

2016-01-01

Definitions of working memory identify it as a function of the executive function system in which an individual maintains two or more pieces of information in mind and uses that information simultaneously for some purpose. In academics, working memory is necessary for a variety of functions, including attending to the information one's teacher presents and then using that information simultaneously for problem solving. Research indicates difficulties with working memory are observed in children with mathematics learning disorder (MLD) and reading disorders (RD). To improve working memory and other executive function difficulties, and as an alternative to medication treatments for attention and executive function disorders, the Motor Cognition(2)® (MC(2)®)program was developed. Preliminary research on this program indicates statistically significant improvements in working memory, mathematics, and nonsense word decoding for reading. Further research on the MC(2)® program and its impact on working memory, as well as other areas of executive functioning, is warranted.

Feedback-Driven Dynamic Invariant Discovery

NASA Technical Reports Server (NTRS)

Zhang, Lingming; Yang, Guowei; Rungta, Neha S.; Person, Suzette; Khurshid, Sarfraz

2014-01-01

Program invariants can help software developers identify program properties that must be preserved as the software evolves, however, formulating correct invariants can be challenging. In this work, we introduce iDiscovery, a technique which leverages symbolic execution to improve the quality of dynamically discovered invariants computed by Daikon. Candidate invariants generated by Daikon are synthesized into assertions and instrumented onto the program. The instrumented code is executed symbolically to generate new test cases that are fed back to Daikon to help further re ne the set of candidate invariants. This feedback loop is executed until a x-point is reached. To mitigate the cost of symbolic execution, we present optimizations to prune the symbolic state space and to reduce the complexity of the generated path conditions. We also leverage recent advances in constraint solution reuse techniques to avoid computing results for the same constraints across iterations. Experimental results show that iDiscovery converges to a set of higher quality invariants compared to the initial set of candidate invariants in a small number of iterations.

Employee Drug Testing. A Single Agency is Needed to Manage Federal Employee Drug Testing

DTIC Science & Technology

1991-02-19

The executive order requires the head of each executive agency to establish a program to test employees in sensitive positions for the use of illegal...that although several agencies were responsible for helping to design employee drug testing programs , there is no federal agency responsible for... EMPLOYEES ARE NOT BEING TREATED EQUITABLY Because the head of each agency is responsible for implementing a drug testing program , the extent to which

Why Army Program Managers Struggle As Life Cycle Managers: A Study of the PM’s Roles, Responsibilities, and Barriers In the Execution of Operations and Support

DTIC Science & Technology

2016-09-01

Support Strategies (PBPSS), throughout the system life cycle .  Maximizing competition, to include small business participation.  Developing...NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA JOINT APPLIED PROJECT WHY ARMY PROGRAM MANAGERS STRUGGLE AS LIFE CYCLE MANAGERS...SUBTITLE WHY ARMY PROGRAM MANAGERS STRUGGLE AS LIFE CYCLE MANAGERS: A STUDY OF THE PM’S ROLES, RESPONSIBILITIES, AND BARRIERS IN THE EXECUTION OF

ADAMS executive and operating system

NASA Technical Reports Server (NTRS)

Pittman, W. D.

1981-01-01

The ADAMS Executive and Operating System, a multitasking environment under which a variety of data reduction, display and utility programs are executed, a system which provides a high level of isolation between programs allowing them to be developed and modified independently, is described. The Airborne Data Analysis/Monitor System (ADAMS) was developed to provide a real time data monitoring and analysis capability onboard Boeing commercial airplanes during flight testing. It inputs sensor data from an airplane performance data by applying transforms to the collected sensor data, and presents this data to test personnel via various display media. Current utilization and future development are addressed.

Dynamic wavefront creation for processing units using a hybrid compactor

DOE Office of Scientific and Technical Information (OSTI.GOV)

Puthoor, Sooraj; Beckmann, Bradford M.; Yudanov, Dmitri

A method, a non-transitory computer readable medium, and a processor for repacking dynamic wavefronts during program code execution on a processing unit, each dynamic wavefront including multiple threads are presented. If a branch instruction is detected, a determination is made whether all wavefronts following a same control path in the program code have reached a compaction point, which is the branch instruction. If no branch instruction is detected in executing the program code, a determination is made whether all wavefronts following the same control path have reached a reconvergence point, which is a beginning of a program code segment tomore » be executed by both a taken branch and a not taken branch from a previous branch instruction. The dynamic wavefronts are repacked with all threads that follow the same control path, if all wavefronts following the same control path have reached the branch instruction or the reconvergence point.« less

BioBlocks: Programming Protocols in Biology Made Easier.

PubMed

Gupta, Vishal; Irimia, Jesús; Pau, Iván; Rodríguez-Patón, Alfonso

2017-07-21

The methods to execute biological experiments are evolving. Affordable fluid handling robots and on-demand biology enterprises are making automating entire experiments a reality. Automation offers the benefit of high-throughput experimentation, rapid prototyping, and improved reproducibility of results. However, learning to automate and codify experiments is a difficult task as it requires programming expertise. Here, we present a web-based visual development environment called BioBlocks for describing experimental protocols in biology. It is based on Google's Blockly and Scratch, and requires little or no experience in computer programming to automate the execution of experiments. The experiments can be specified, saved, modified, and shared between multiple users in an easy manner. BioBlocks is open-source and can be customized to execute protocols on local robotic platforms or remotely, that is, in the cloud. It aims to serve as a de facto open standard for programming protocols in Biology.

Integrated verification and testing system (IVTS) for HAL/S programs

NASA Technical Reports Server (NTRS)

Senn, E. H.; Ames, K. R.; Smith, K. A.

1983-01-01

The IVTS is a large software system designed to support user-controlled verification analysis and testing activities for programs written in the HAL/S language. The system is composed of a user interface and user command language, analysis tools and an organized data base of host system files. The analysis tools are of four major types: (1) static analysis, (2) symbolic execution, (3) dynamic analysis (testing), and (4) documentation enhancement. The IVTS requires a split HAL/S compiler, divided at the natural separation point between the parser/lexical analyzer phase and the target machine code generator phase. The IVTS uses the internal program form (HALMAT) between these two phases as primary input for the analysis tools. The dynamic analysis component requires some way to 'execute' the object HAL/S program. The execution medium may be an interpretive simulation or an actual host or target machine.

Using DGGE and 16S rRNA gene sequence analysis to evaluate changes in oral bacterial composition.

PubMed

Chen, Zhou; Trivedi, Harsh M; Chhun, Nok; Barnes, Virginia M; Saxena, Deepak; Xu, Tao; Li, Yihong

2011-01-01

To investigate whether a standard dental prophylaxis followed by tooth brushing with an antibacterial dentifrice will affect the oral bacterial community, as determined by denaturing gradient gel electrophoresis (DGGE) combined with 16S rRNA gene sequence analysis. Twenty-four healthy adults were instructed to brush their teeth using commercial dentifrice for 1 week during a washout period. An initial set of pooled supragingival plaque samples was collected from each participant at baseline (0 h) before prophylaxis treatment. The subjects were given a clinical examination and dental prophylaxis and asked to brush for 1 min with a dentifrice containing 0.3% triclosan, 2.0% PVM/MA copolymer and 0.243% sodium fluoride (Colgate Total). On the following day, a second set of pooled supragingival plaque samples (24 h) was collected. Total bacterial genomic DNA was isolated from the samples. Differences in the microbial composition before and after the prophylactic procedure and tooth brushing were assessed by comparing the DGGE profiles and 16S rRNA gene segments sequence analysis. Two distinct clusters of DGGE profiles were found, suggesting that a shift in the microbial composition had occurred 24 h after the prophylaxis and brushing. A detailed sequencing analysis of 16S rRNA gene segments further identified 6 phyla and 29 genera, including known and unknown bacterial species. Importantly, an increase in bacterial diversity was observed after 24 h, including members of the Streptococcaceae family, Prevotella, Corynebacterium, TM7 and other commensal bacteria. The results suggest that the use of a standard prophylaxis followed by the use of the dentifrice containing 0.3% triclosan, 2.0% PVM/MA copolymer and 0.243% sodium fluoride may promote a healthier composition within the oral bacterial community.

The Rhoptry Proteins ROP18 and ROP5 Mediate Toxoplasma gondii Evasion of the Murine, But Not the Human, Interferon-Gamma Response

PubMed Central

Niedelman, Wendy; Gold, Daniel A.; Rosowski, Emily E.; Sprokholt, Joris K.; Lim, Daniel; Farid Arenas, Ailan; Melo, Mariane B.; Spooner, Eric; Yaffe, Michael B.; Saeij, Jeroen P. J.

2012-01-01

The obligate intracellular parasite Toxoplasma gondii secretes effector proteins into the host cell that manipulate the immune response allowing it to establish a chronic infection. Crosses between the types I, II and III strains, which are prevalent in North America and Europe, have identified several secreted effectors that determine strain differences in mouse virulence. The polymorphic rhoptry protein kinase ROP18 was recently shown to determine the difference in virulence between type I and III strains by phosphorylating and inactivating the interferon-γ (IFNγ)-induced immunity-related GTPases (IRGs) that promote killing by disrupting the parasitophorous vacuole membrane (PVM) in murine cells. The polymorphic pseudokinase ROP5 determines strain differences in virulence through an unknown mechanism. Here we report that ROP18 can only inhibit accumulation of the IRGs on the PVM of strains that also express virulent ROP5 alleles. In contrast, specific ROP5 alleles can reduce IRG coating even in the absence of ROP18 expression and can directly interact with one or more IRGs. We further show that the allelic combination of ROP18 and ROP5 also determines IRG evasion and virulence of strains belonging to other lineages besides types I, II and III. However, neither ROP18 nor ROP5 markedly affect survival in IFNγ-activated human cells, which lack the multitude of IRGs present in murine cells. These findings suggest that ROP18 and ROP5 have specifically evolved to block the IRGs and are unlikely to have effects in species that do not have the IRG system, such as humans. PMID:22761577

Effect of a single brushing with two Zn-containing toothpastes on VSC in morning breath: a 12 h, randomized, double-blind, cross-over clinical study.

PubMed

Young, A; Jonski, G

2011-12-01

This randomized, double-blind, 12 h clinical study tested the effect of a single brushing with two Zn-containing toothpastes on volatile sulfur compound (VSC) levels in morning breath. The following toothpastes were each tested by all 28 participants: A-Zn toothpaste, B--experimental toothpaste (Zn citrate + PVM/MA copolymer) and C--control toothpaste without Zn. The evening prior to test days participants brushed their teeth for 2 min with 1 g toothpaste. 12 h later and prior to eating or performing oral hygiene, morning breath levels of VSC (H(2)S, CH(3)SH) were analysed by gas chromatography. Subjects then rinsed for 30 s with 5 ml cysteine and breath samples were analysed for H(2)S (H(2)S(cys)). Median VSC (area under the curve) values were compared for A, B and C and the effects of A and B on VSC were compared with C. Toothpaste B was more effective than both toothpastes A and C in reducing H(2)S, CH(3)SH and H(2)S(cys) (p < 0.05). Compared with toothpaste C, toothpastes A and B reduced H(2)S by 35% and 68%, respectively (p = 0.003), and CH(3)SH by 12% and 47%, respectively (p = 0.002). Toothpaste B reduced H(2)S(cys) by 48% compared with toothpaste C (p = 0.001). It is suggested that the superior effect of the experimental toothpaste was most likely due to a higher Zn concentration combined with longer retention of Zn due to the PVM/MA copolymer.

Real-time monitoring of the mechanism of ibuprofen-cationic dextran crystanule formation using crystallization process informatics system (CryPRINS).

PubMed

Abioye, Amos Olusegun; Chi, George Tangyie; Simone, Elena; Nagy, Zoltan

2016-07-25

One step aqueous melt-crystallization and in situ granulation was utilized to produce ibuprofen-cationic dextran [diethylaminoethyl dextran (Ddex)] conjugate crystanules without the use of surfactants or organic solvents. This study investigates the mechanism of in situ granulation-induced crystanule formation using ibuprofen (Ibu) and Ddex. Laboratory scale batch aqueous crystallization system containing in situ monitoring probes for particle vision measurement (PVM), UV-vis measurement and focused beam reflectance measurements (FBRM) was adapted using pre-defined formulation and process parameters. Pure ibuprofen showed nucleation domain between 25 and 64°C, producing minicrystals with onset of melting at 76°C and enthalpy of fusion (ΔH) of 26.22kJ/mol. On the other hand Ibu-Ddex crystanules showed heterogeneous nucleation which produced spherical core-shell structure. PVM images suggest that internalization of ibuprofen in Ddex corona occurred during the melting phase (before nucleation) which inhibited crystal growth inside the Ddex corona. The remarkable decrease in ΔH of the crystanules from 26.22 to 11.96kJ/mol and the presence of broad overlapping DSC thermogram suggests formation of ibuprofen-Ddex complex and crystalline-amorphous transformation. However Raman and FTIR spectra did not show any significant chemical interaction between ibuprofen and Ddex. A significant increase in dissolution efficiency from 45 to 81% within 24h and reduced burst release provide evidence for potential application of crystanules in controlled drug delivery systems. It was evident that in situ granulation of ibuprofen inhibited the aqueous crystallization process. It was concluded that in situ granulation-aqueous crystallization technique is a novel unit operation with potential application in continuous pharmaceutical processing. Copyright © 2016 Elsevier B.V. All rights reserved.

Evaluation of feature-based 3-d registration of probabilistic volumetric scenes

NASA Astrophysics Data System (ADS)

Restrepo, Maria I.; Ulusoy, Ali O.; Mundy, Joseph L.

2014-12-01

Automatic estimation of the world surfaces from aerial images has seen much attention and progress in recent years. Among current modeling technologies, probabilistic volumetric models (PVMs) have evolved as an alternative representation that can learn geometry and appearance in a dense and probabilistic manner. Recent progress, in terms of storage and speed, achieved in the area of volumetric modeling, opens the opportunity to develop new frameworks that make use of the PVM to pursue the ultimate goal of creating an entire map of the earth, where one can reason about the semantics and dynamics of the 3-d world. Aligning 3-d models collected at different time-instances constitutes an important step for successful fusion of large spatio-temporal information. This paper evaluates how effectively probabilistic volumetric models can be aligned using robust feature-matching techniques, while considering different scenarios that reflect the kind of variability observed across aerial video collections from different time instances. More precisely, this work investigates variability in terms of discretization, resolution and sampling density, errors in the camera orientation, and changes in illumination and geographic characteristics. All results are given for large-scale, outdoor sites. In order to facilitate the comparison of the registration performance of PVMs to that of other 3-d reconstruction techniques, the registration pipeline is also carried out using Patch-based Multi-View Stereo (PMVS) algorithm. Registration performance is similar for scenes that have favorable geometry and the appearance characteristics necessary for high quality reconstruction. In scenes containing trees, such as a park, or many buildings, such as a city center, registration performance is significantly more accurate when using the PVM.

Architectural constructs of Ampex DST

NASA Technical Reports Server (NTRS)

Johnson, Clay

1993-01-01

The DST 800 automated library is a high performance, automated tape storage system, developed by AMPEX, providing mass storage to host systems. Physical Volume Manager (PVM) is a volume server which supports either a DST 800, DST 600 stand alone tape drive, or a combination of DST 800 and DST 600 subsystems. The objective of the PVM is to provide the foundation support to allow automated and operator assisted access to the DST cartridges with continuous operation. A second objective is to create a data base about the media, its location, and its usage so that the quality and utilization of the media on which specific data is recorded and the performance of the storage system may be managed. The DST tape drive architecture and media provides several unique functions that enhance the ability to achieve high media space utilization and fast access. Access times are enhanced through the implementation of multiple areas (called system zones) on the media where the media may be unloaded. This reduces positioning time in loading and unloading the cartridge. Access times are also reduced through high speed positioning in excess of 800 megabytes per second. A DST cartridge can be partitioned into fixed size units which can be reclaimed for rewriting without invalidating other recorded data on the tape cartridge. Most tape management systems achieve space reclamation by deleting an entire tape volume, then allowing users to request a 'scratch tape' or 'nonspecific' volume when they wish to record data to tape. Physical cartridge sizes of 25, 75, or 165 gigabytes will make this existing process inefficient or unusable. The DST cartridge partitioning capability provides an efficient mechanism for addressing the tape space utilization problem.

36 CFR 1231.12 - How do executive agencies request to transfer records to another executive agency?

Code of Federal Regulations, 2010 CFR

2010-07-01

... Administration, Modern Records Programs (NWM), 8601 Adelphi Road, College Park, MD 20740-6001, phone number (301... request to transfer records to another executive agency? 1231.12 Section 1231.12 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT TRANSFER OF RECORDS FROM...

36 CFR 1231.12 - How do executive agencies request to transfer records to another executive agency?

Code of Federal Regulations, 2012 CFR

2012-07-01

... Administration, Modern Records Programs (NWM), 8601 Adelphi Road, College Park, MD 20740-6001, phone number (301... request to transfer records to another executive agency? 1231.12 Section 1231.12 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT TRANSFER OF RECORDS FROM...

36 CFR 1231.12 - How do executive agencies request to transfer records to another executive agency?

Code of Federal Regulations, 2011 CFR

2011-07-01

... Administration, Modern Records Programs (NWM), 8601 Adelphi Road, College Park, MD 20740-6001, phone number (301... request to transfer records to another executive agency? 1231.12 Section 1231.12 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT TRANSFER OF RECORDS FROM...

36 CFR 1231.12 - How do executive agencies request to transfer records to another executive agency?

Code of Federal Regulations, 2014 CFR

2014-07-01

... Administration, Modern Records Programs (NWM), 8601 Adelphi Road, College Park, MD 20740-6001, phone number (301... request to transfer records to another executive agency? 1231.12 Section 1231.12 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT TRANSFER OF RECORDS FROM...

Reading Comprehension and Working Memory's Executive Processes: An Intervention Study in Primary School Students

ERIC Educational Resources Information Center

Garcia-Madruga, Juan A.; Elosua, Maria Rosa; Gil, Laura; Gomez-Veiga, Isabel; Vila, Jose Oscar; Orjales, Isabel; Contreras, Antonio; Rodriguez, Raquel; Melero, Maria Angeles; Duque, Gonzalo

2013-01-01

Reading comprehension is a highly demanding task that involves the simultaneous process of extracting and constructing meaning in which working memory's executive processes play a crucial role. In this article, a training program on working memory's executive processes to improve reading comprehension is presented and empirically tested in two…

The Role of Mentoring in Fostering Executive Function, Effort, and Academic Self-Concept

ERIC Educational Resources Information Center

Meltzer, Lynn; Basho, Surina; Reddy, Ranjini; Kurkul, Katelyn

2015-01-01

This exploratory study examined the impact of an in-school intervention program that blends peer mentoring with executive function strategy instruction for at-risk learners. More specifically, the study focused on evaluating the effects of the SMARTS Executive Function and Mentoring intervention on students' strategy use, effort, academic…

Executive Energy Leadership Academy | NREL

Science.gov Websites

Management-Development, EDF Renewable Energy, Class of 2017 Executive Energy Leadership Academy Alumni Since Energy Leadership Academy. See the list of alumni sorted by program and year

DORMAN computer program (study 2.5). Volume 1: Executive summary. [development of data bank for computerized information storage of NASA programs

NASA Technical Reports Server (NTRS)

Stricker, L. T.

1973-01-01

The DORCA Applications study has been directed at development of a data bank management computer program identified as DORMAN. Because of the size of the DORCA data files and the manipulations required on that data to support analyses with the DORCA program, automated data techniques to replace time-consuming manual input generation are required. The Dynamic Operations Requirements and Cost Analysis (DORCA) program was developed for use by NASA in planning future space programs. Both programs are designed for implementation on the UNIVAC 1108 computing system. The purpose of this Executive Summary Report is to define for the NASA management the basic functions of the DORMAN program and its capabilities.

WWC Review of the Report "Effects of the FITKids Randomized Controlled Trial on Executive Control and Brain Function." What Works Clearinghouse Single Study Review

ERIC Educational Resources Information Center

What Works Clearinghouse, 2015

2015-01-01

This study measured the impact of the "Fitness Improves Thinking in Kids" ("FITKids") afterschool program on the executive control (i.e., maintaining focus, performing multiple cognitive processes) and physical fitness of preadolescent students. The "FITKids" program was held at the University of Illinois' campus and…

JWST Program Implementation

NASA Astrophysics Data System (ADS)

Januszewski, William

2018-01-01

This poster will feature what is involved in preparing a James Webb Space Telescope program for execution on board the spacecraft. The process from when the principle investigator hits the submit button to when the observations are executed on board the spacecraft will be addressed. Although the process shares a number of sumilarities with the implementation process for the Hubble Space Telescope, there are significant differences.

An Examination of Middle School Agricultural Education and FFA Programs: Survey Results from State FFA Executive Secretaries.

ERIC Educational Resources Information Center

Rossetti, Rosemarie; McCaslin, N. L.

A study collected information from 52 of the 53 state Future Farmers of America (FFA) executive secretaries who were sent questionnaires on middle school student enrollment in agricultural education and membership in the national FFA organization. Results showed that 30 states have agricultural education programs in the middle school level, with a…

A Best Practice Modular Design of a Hybrid Course Delivery Structure for an Executive Education Program

ERIC Educational Resources Information Center

Klotz, Dorothy E.; Wright, Thomas A.

2017-01-01

This article highlights a best practice approach that showcases the highly successful deployment of a hybrid course delivery structure for an Operations core course in an Executive MBA Program. A key design element of the approach was the modular design of both the course itself and the learning materials. While other hybrid deployments may stress…

Common Ground: Discursive Practices and the Building of Trust among Participants of Executive Training Programs

ERIC Educational Resources Information Center

Thomas, Christopher Allen

2016-01-01

In traditional academic instruction, the classroom may be viewed as a kind of speech community composed of an expert (the teacher) and those who are at various stages of socializing into the cultural models and norms of that community (students), although this is an overly simplistic and unilinear view. In executive development programs, students…

The Automated Instrumentation and Monitoring System (AIMS): Design and Architecture. 3.2

NASA Technical Reports Server (NTRS)

Yan, Jerry C.; Schmidt, Melisa; Schulbach, Cathy; Bailey, David (Technical Monitor)

1997-01-01

Whether a researcher is designing the 'next parallel programming paradigm', another 'scalable multiprocessor' or investigating resource allocation algorithms for multiprocessors, a facility that enables parallel program execution to be captured and displayed is invaluable. Careful analysis of such information can help computer and software architects to capture, and therefore, exploit behavioral variations among/within various parallel programs to take advantage of specific hardware characteristics. A software tool-set that facilitates performance evaluation of parallel applications on multiprocessors has been put together at NASA Ames Research Center under the sponsorship of NASA's High Performance Computing and Communications Program over the past five years. The Automated Instrumentation and Monitoring Systematic has three major software components: a source code instrumentor which automatically inserts active event recorders into program source code before compilation; a run-time performance monitoring library which collects performance data; and a visualization tool-set which reconstructs program execution based on the data collected. Besides being used as a prototype for developing new techniques for instrumenting, monitoring and presenting parallel program execution, AIMS is also being incorporated into the run-time environments of various hardware testbeds to evaluate their impact on user productivity. Currently, the execution of FORTRAN and C programs on the Intel Paragon and PALM workstations can be automatically instrumented and monitored. Performance data thus collected can be displayed graphically on various workstations. The process of performance tuning with AIMS will be illustrated using various NAB Parallel Benchmarks. This report includes a description of the internal architecture of AIMS and a listing of the source code.

Analysis of Interactive Graphics Display Equipment for an Automated Photo Interpretation System.

DTIC Science & Technology

1982-06-01

System provides the hardware and software for a range of graphics processor tasks. The IMAGE System employs the RSX- II M real - time operating . system in...One hard copy unit serves up to four work stations. The executive program of the IMAGE system is the DEC RSX- 11 M real - time operating system . In...picture controller. The PDP 11/34 executes programs concurrently under the RSX- I IM real - time operating system . Each graphics program consists of a

American Organization of Nurse Executives Care Innovation and Transformation program: improving care and practice environments.

PubMed

Oberlies, Amanda Stefancyk

2014-09-01

The American Organization of Nurse Executives conducted an evaluation of the hospitals participating in the Care Innovation and Transformation (CIT) program. A total of 24 hospitals participated in the 2-year CIT program from 2012 to 2013. Reported outcomes include increased patient satisfaction, decreased falls, and reductions in nurse turnover and overtime. Nurses reported statistically significant improvements in 4 domains of the principles and elements of a healthful practice environment developed by the Nursing Organizations Alliance.

Using State Merging and State Pruning to Address the Path Explosion Problem Faced by Symbolic Execution

DTIC Science & Technology

2014-06-19

urgent and compelling. Recent efforts in this area automate program analysis techniques using model checking and symbolic execution [2, 5–7]. These...bounded model checking tool for x86 binary programs developed at the Air Force Institute of Technology (AFIT). Jiseki creates a bit-vector logic model based...assume there are n different paths through the function foo . The program could potentially call the function foo a bound number of times, resulting in n

The effect of small-sided games with different levels of opposition on the tactical behaviour of young footballers with different levels of sport expertise.

PubMed

Práxedes, Alba; Moreno, Alberto; Gil-Arias, Alexander; Claver, Fernando; Del Villar, Fernando

2018-01-01

To optimize players' tactical abilities, coaches need to design training sessions with representative learning tasks, such as, small-sided games. Moreover, it is necessary to adapt the complexity of the tasks to the skill level of the athletes to maximally improve their perceptual, visual and attentive abilities. The objective of this study was to analyze the effect of two teaching programs, each utilizing modified games with varied levels of opposition, on decision-making and action execution in young players with different levels of sports expertise. 19 football players (U12), separated into two ability groups (Average versus Low skill-level), participated in a series of training sessions that were spread over 4 phases: Pre-intervention 1, Intervention 1 (teaching program based on modified games with numerical superiority in attack), Pre-intervention 2 and Intervention 2 (teaching program based on modified games with numerical equality). Each intervention phase lasted 14 sessions. Decision-making and the execution of pass action during league matches over the same period were evaluated using the Game Performance Evaluation Tool (GPET). The Average skill-level group showed significant differences after the first intervention in decision-making and execution of the pass action (decision-making, p = .015; execution, p = .031), but not after the second intervention (decision-making, p = 1.000; execution, p = 1.000). For the Low skill-level group, significant differences were only observed in the execution of passing between the first and last phases (p = .014). These findings seem to indicate that for groups with an average level of expertise, training with numerical superiority in attack provides players with more time to make better decisions and to better execute actions. However, for lower-level groups programs may take longer to facilitate improvement. Nevertheless, numerical equality did not result in improvement for either group.

Traditional versus rule-based programming techniques: Application to the control of optional flight information

NASA Technical Reports Server (NTRS)

Ricks, Wendell R.; Abbott, Kathy H.

1987-01-01

To the software design community, the concern over the costs associated with a program's execution time and implementation is great. It is always desirable, and sometimes imperative, that the proper programming technique is chosen which minimizes all costs for a given application or type of application. A study is described that compared cost-related factors associated with traditional programming techniques to rule-based programming techniques for a specific application. The results of this study favored the traditional approach regarding execution efficiency, but favored the rule-based approach regarding programmer productivity (implementation ease). Although this study examined a specific application, the results should be widely applicable.

A Guide to Axial-Flow Turbine Off-Design Computer Program AXOD2

NASA Technical Reports Server (NTRS)

Chen, Shu-Cheng S.

2014-01-01

A Users Guide for the axial flow turbine off-design computer program AXOD2 is composed in this paper. This Users Guide is supplementary to the original Users Manual of AXOD. Three notable contributions of AXOD2 to its predecessor AXOD, both in the context of the Guide or in the functionality of the code, are described and discussed in length. These are: 1) a rational representation of the mathematical principles applied, with concise descriptions of the formulas implemented in the actual coding. Their physical implications are addressed; 2) the creation and documentation of an Addendum Listing of input namelist-parameters unique to AXOD2, that differ from or are in addition to the original input-namelists given in the Manual of AXOD. Their usages are discussed; and 3) the institution of proper stoppages of the code execution, encoding termination messaging and error messages of the execution to AXOD2. These measures are to safe-guard the integrity of the code execution, such that a failure mode encountered during a case-study would not plunge the code execution into indefinite loop, or cause a blow-out of the program execution. Details on these are discussed and illustrated in this paper. Moreover, this computer program has since been reconstructed substantially. Standard FORTRAN Langue was instituted, and the code was formatted in Double Precision (REAL*8). As the result, the code is now suited for use in a local Desktop Computer Environment, is perfectly portable to any Operating System, and can be executed by any FORTRAN compiler equivalent to a FORTRAN 9095 compiler. AXOD2 will be available through NASA Glenn Research Center (GRC) Software Repository.

CELFE: Coupled Eulerian-Lagrangian Finite Element program for high velocity impact. Part 2: Program user's manual

NASA Technical Reports Server (NTRS)

Lee, C. H.

1978-01-01

The CELFE computer program and user's manual, together with the execution of the CELFE/NASTRAN system, are described. The execution procedure and the transfer of data between the CELFE and NASTRAN programs are controlled through the use of DATA files in the Univac 1100 system. Five data files are used to control the runstream and data transfer, and three files are used to hold the programs. These files are contained on a single tape. Changes in NASTRAN routines required by the present analysis are also discussed in this report. All the program listings, except the last two files (where the absolute and relocatable elements are stored), are included in the appendixes.

Users manual for flight control design programs

NASA Technical Reports Server (NTRS)

Nalbandian, J. Y.

1975-01-01

Computer programs for the design of analog and digital flight control systems are documented. The program DIGADAPT uses linear-quadratic-gaussian synthesis algorithms in the design of command response controllers and state estimators, and it applies covariance propagation analysis to the selection of sampling intervals for digital systems. Program SCHED executes correlation and regression analyses for the development of gain and trim schedules to be used in open-loop explicit-adaptive control laws. A linear-time-varying simulation of aircraft motions is provided by the program TVHIS, which includes guidance and control logic, as well as models for control actuator dynamics. The programs are coded in FORTRAN and are compiled and executed on both IBM and CDC computers.

Management development: a needs analysis for nurse executives and managers.

PubMed

Kirk, R

1987-04-01

Clearly, both the nurse executive and nurse manager roles are becoming more complex. I feel an enthusiasm by the professionals in those positions to pursue development activities that will help them do their jobs better and with less discomfort. Nurse executives obviously know the power of combining knowledge with experience. How do the different leadership and management development needs identified by these NE fit with your organization's needs? What is the content in your leadership and management development programs? Are your programs meeting the real needs of your executive and management-level staff? One way to find out is to do a simple survey. Today, nurse executives are responsible and accountable for challenges we never considered possible, even a few years ago. But along with the new challenges came the flexibility and positive attitudes of NEs to respond to changes and acquire new skills such as cost accounting, computers, or marketing. It's this type of proactive thinking that helps nurse leaders turn problems into opportunities and their situations into success stories.

Public reporting and pay-for-performance: safety-net hospital executives' concerns and policy suggestions.

PubMed

Goldman, L Elizabeth; Henderson, Stuart; Dohan, Daniel P; Talavera, Jason A; Dudley, R Adams

2007-01-01

Safety-net hospitals (SNHs) may gain little financial benefit from the rapidly spreading adoption of public reporting and pay-for-performance, but may feel compelled to participate (and bear the costs of data collection) to meet public expectations of transparency and accountability. To better understand the concerns that SNH administrators have regarding public reporting and pay-for-performance, we interviewed 37 executives at randomly selected California SNHs. The main concerns noted by SNH executives were that human and financial resource constraints made it difficult for SNHs to accurately measure their performance. Additionally, some executives felt that market-driven public reporting and pay-for-performance may focus on clinical areas and incentive structures that may not be high-priority clinical areas for SNHs. Executives at SNHs suggested several policy responses to these concerns-such as offering training programs for SNH data collectors-that could be relatively inexpensive and might improve the cost-benefit ratio of public reporting and pay-for-performance programs.

Crystallographic and general use programs for the XDS Sigma 5 computer

NASA Technical Reports Server (NTRS)

Snyder, R. L.

1973-01-01

Programs in basic FORTRAN 4 are described, which fall into three catagories: (1) interactive programs to be executed under time sharing (BTM); (2) non interactive programs which are executed in batch processing mode (BPM); and (3) large non interactive programs which require more memory than is available in the normal BPM/BTM operating system and must be run overnight on a special system called XRAY which releases about 45,000 words of memory to the user. Programs in catagories (1) and (2) are stored as FORTRAN source files in the account FSNYDER. Programs in catagory (3) are stored in the XRAY system as load modules. The type of file in account FSNYDER is identified by the first two letters in the name.

Synthesizing information-update functions using off-line symbolic processing

NASA Technical Reports Server (NTRS)

Rosenschein, Stanley J.

1990-01-01

This paper explores the synthesis of programs that track dynamic conditions in their environment. An approach is proposed in which the designer specifies, in a declarative language, aspects of the environment in which the program will be embedded. This specification is then automatically compiled into a program that, when executed, updates internal data structures so as to maintain as an invariant a desired correspondence between internal data structures and states of the external environment. This approach retains much of the flexibility of declarative programming while guaranteeing a hard bound on the execution time of information-update functions.

78 FR 43923 - Solicitation for a Cooperative Agreement-Executive Excellence a Training and Development Program...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-22

... demonstrated the potential to be the chief executive officer at the state, local or federal level. The... experience as a correctional or criminal justice chief executive officer, completed the current curriculum of... Correctional Leadership for the 21st Century, a portion of which specifically addresses the role of the...

7 CFR 1410.53 - Executed CRP contract not in conformity with regulations.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false Executed CRP contract not in conformity with... RESERVE PROGRAM § 1410.53 Executed CRP contract not in conformity with regulations. If, after a CRP contract is approved by CCC, it is discovered that such CRP contract is found to contain material errors of...

36 CFR § 1231.12 - How do executive agencies request to transfer records to another executive agency?

Code of Federal Regulations, 2013 CFR

2013-07-01

... Administration, Modern Records Programs (NWM), 8601 Adelphi Road, College Park, MD 20740-6001, phone number (301... request to transfer records to another executive agency? § 1231.12 Section § 1231.12 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION RECORDS MANAGEMENT TRANSFER OF RECORDS FROM...

The Effects of Learning Communities for Students in Developmental Education: A Synthesis of Findings from Six Community Colleges. Executive Summary

ERIC Educational Resources Information Center

Visher, Mary G.; Weiss, Michael J.; Weissman, Evan; Rudd, Timothy; Wathington, Heather D.

2012-01-01

In 2006, the National Center for Postsecondary Research, of which is MDRC is a partner, launched a demonstration of one-semester learning community programs at six colleges; five of these programs focused on developmental education. This is the executive summary of the final report from the project and includes findings from analyses that pool…

Findings from the Evaluation of the National Library Power Program. Executive Summary. An Initiative of the DeWitt Wallace-Reader's Digest Fund.

ERIC Educational Resources Information Center

Zweizig, Douglas; Hopkins, Dianne McAfee

This document presents the executive summary of an evaluation of Library Power, a program of the DeWitt Wallace-Reader's Digest Fund to enhance and elevate the role of libraries in public schools. The report begins with an examination of Library Power's core components (collection development, facilities refurbishing, flexible scheduling,…

Effectiveness Testing and Evaluation of Non-Lethal Weapons for Crowd Management

DTIC Science & Technology

2014-06-01

and Combat Service Support• Program Executive Office Ground Combat Systems • Program Executive Office Soldier TACOM LCMC MG Michael J. Terry Assigned...technologies and explosive ordnance disposal Fire Control: Battlefield digitization; embedded system software; aero ballistics and telemetry ARDEC...influence predictive variables Introduction Crowd Behavior Research at TBRL UNCLASSIFIED 7 Data Measurement • Vicon V8i system • 24 cameras • 120 fps

Benefits of Exercise on the Executive Functions in People with Parkinson Disease: A Controlled Clinical Trial.

PubMed

de Oliveira, Renata Terra; Felippe, Lilian Assunção; Bucken Gobbi, Lilian Teresa; Barbieri, Fabio Augusto; Christofoletti, Gustavo

2017-05-01

We have made a 3-arm trial (group vs. individual exercise vs. no treatment) to test the effects of a 6-month exercise program upon the executive functions in participants with Parkinson disease. Twenty-four subjects were randomly allocated in 3 groups and undertook individualized exercises (G1, n = 8), group exercises (G2, n = 8), or monitoring (G3, n = 8). Executive functions were evaluated by means of the Wisconsin card sorting test and the Raven colored matrices, both assessed at the beginning of the program and after 6 months. The statistical analyses consisted of the application of repeated measurement tests, with a significant level of 5%. The findings showed similar behavior of groups in terms of the Wisconsin card sorting test (P = 0.792), reporting no benefit of the program on such instrument. Differently, Raven colored matrices evidenced a significant benefit provided by the intervention (P = 0.032). Compared with the control group, individuals from G1 had a substantial improvement on executive functions (P = 0.031) and from G2 had a trend of significance (P = 0.072). Findings of this study show that 6 months of exercise improved some aspects of executive functions when compared with control peers. Individual therapy seems to have a more prominent improvement than group therapy.

: A Scalable and Transparent System for Simulating MPI Programs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Perumalla, Kalyan S

2010-01-01

is a scalable, transparent system for experimenting with the execution of parallel programs on simulated computing platforms. The level of simulated detail can be varied for application behavior as well as for machine characteristics. Unique features of are repeatability of execution, scalability to millions of simulated (virtual) MPI ranks, scalability to hundreds of thousands of host (real) MPI ranks, portability of the system to a variety of host supercomputing platforms, and the ability to experiment with scientific applications whose source-code is available. The set of source-code interfaces supported by is being expanded to support a wider set of applications, andmore » MPI-based scientific computing benchmarks are being ported. In proof-of-concept experiments, has been successfully exercised to spawn and sustain very large-scale executions of an MPI test program given in source code form. Low slowdowns are observed, due to its use of purely discrete event style of execution, and due to the scalability and efficiency of the underlying parallel discrete event simulation engine, sik. In the largest runs, has been executed on up to 216,000 cores of a Cray XT5 supercomputer, successfully simulating over 27 million virtual MPI ranks, each virtual rank containing its own thread context, and all ranks fully synchronized by virtual time.« less

A Case Study for Executive Leadership

ERIC Educational Resources Information Center

Hill, Phyllis J.

1975-01-01

A newly appointed woman dean discusses the value of a management development program involving a process of self-analysis and self-determination of leadership style and effectiveness (the University of Illinois "Executive Leadership Seminar"). (JT)

Image Display and Manipulation System (IDAMS) program documentation, Appendixes A-D. [including routines, convolution filtering, image expansion, and fast Fourier transformation

NASA Technical Reports Server (NTRS)

Cecil, R. W.; White, R. A.; Szczur, M. R.

1972-01-01

The IDAMS Processor is a package of task routines and support software that performs convolution filtering, image expansion, fast Fourier transformation, and other operations on a digital image tape. A unique task control card for that program, together with any necessary parameter cards, selects each processing technique to be applied to the input image. A variable number of tasks can be selected for execution by including the proper task and parameter cards in the input deck. An executive maintains control of the run; it initiates execution of each task in turn and handles any necessary error processing.

Evaluation of Robotic Systems to Carry Out Traverse Execution, Opportunistic Science, and Landing Site Evaluation Tasks

NASA Technical Reports Server (NTRS)

Hoffman, Stephen J.; Leonard, Matther J.; Pacal, Lee

2011-01-01

This report covers the execution of and results from the activities proposed and approved in Exploration Analogs and Mission Development (EAMD) Field Test Protocol HMP2010: Evaluation of Robotic Systems to carry out Traverse Execution, Opportunistic Science, and Landing Site Evaluation Tasks. The field tests documented in this report examine one facet of a larger program of planetary surface exploration. This program has been evolving and maturing for several years, growing from a broad policy statement with a few specified milestones for NASA to an international effort with much higher fidelity descriptions of systems and operations necessary to accomplish this type of exploration.

The chief information officer--capturing healthcare's rare bird.

PubMed

Krinsky, M L

1986-08-01

While we occasionally conducted MIS executive searches during the 1970s, the recent pace has quickened substantially. Healthcare corporations need the MIS executive or CIO to keep the organization technologically and managerially current. Downsizing of acute-care facilities, expansion of outpatient services and creation of new programs have put a premium on current, computer-generated data. Skilled managers must rely on an efficient, flexible data processing department to evaluate options and make decisions about corporate strategy and program development. A presentable, articulate, personable MIS executive is a key ingredient in a successful management team. The position will continue to grow in importance and prominence in the fast-changing healthcare delivery industry.

Accounting utility for determining individual usage of production level software systems

NASA Technical Reports Server (NTRS)

Garber, S. C.

1984-01-01

An accounting package was developed which determines the computer resources utilized by a user during the execution of a particular program and updates a file containing accumulated resource totals. The accounting package is divided into two separate programs. The first program determines the total amount of computer resources utilized by a user during the execution of a particular program. The second program uses these totals to update a file containing accumulated totals of computer resources utilized by a user for a particular program. This package is useful to those persons who have several other users continually accessing and running programs from their accounts. The package provides the ability to determine which users are accessing and running specified programs along with their total level of usage.

High level language-based robotic control system

NASA Technical Reports Server (NTRS)

Rodriguez, Guillermo (Inventor); Kruetz, Kenneth K. (Inventor); Jain, Abhinandan (Inventor)

1994-01-01

This invention is a robot control system based on a high level language implementing a spatial operator algebra. There are two high level languages included within the system. At the highest level, applications programs can be written in a robot-oriented applications language including broad operators such as MOVE and GRASP. The robot-oriented applications language statements are translated into statements in the spatial operator algebra language. Programming can also take place using the spatial operator algebra language. The statements in the spatial operator algebra language from either source are then translated into machine language statements for execution by a digital control computer. The system also includes the capability of executing the control code sequences in a simulation mode before actual execution to assure proper action at execution time. The robot's environment is checked as part of the process and dynamic reconfiguration is also possible. The languages and system allow the programming and control of multiple arms and the use of inward/outward spatial recursions in which every computational step can be related to a transformation from one point in the mechanical robot to another point to name two major advantages.

High level language-based robotic control system

NASA Technical Reports Server (NTRS)

Rodriguez, Guillermo (Inventor); Kreutz, Kenneth K. (Inventor); Jain, Abhinandan (Inventor)

1996-01-01

This invention is a robot control system based on a high level language implementing a spatial operator algebra. There are two high level languages included within the system. At the highest level, applications programs can be written in a robot-oriented applications language including broad operators such as MOVE and GRASP. The robot-oriented applications language statements are translated into statements in the spatial operator algebra language. Programming can also take place using the spatial operator algebra language. The statements in the spatial operator algebra language from either source are then translated into machine language statements for execution by a digital control computer. The system also includes the capability of executing the control code sequences in a simulation mode before actual execution to assure proper action at execution time. The robot's environment is checked as part of the process and dynamic reconfiguration is also possible. The languages and system allow the programming and control of multiple arms and the use of inward/outward spatial recursions in which every computational step can be related to a transformation from one point in the mechanical robot to another point to name two major advantages.

Perceived Effectiveness of Internal Executive Coaching Engagements by Participants in a High Potential Leadership Development Program

ERIC Educational Resources Information Center

Figlar, Marilyn Elizabeth Kraus

2014-01-01

The field of executive coaching has grown in popularity as a developmental tool for leaders. With the potential for a leadership continuity gap and the desire for organizations to strengthen leadership talent pools to prepare for succession planning, there is a need for empirical research regarding the effectiveness of executive coaching. The aim…

77 FR 40793 - West Virginia Regulatory Program

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-11

... enumerated in Senate Bill 579 will ease the strain placed on the Fund. Formatting and style changes have been... is exempt from review by the Office of Management and Budget under Executive Order 12866. Executive...

A Tutorial on Parallel and Concurrent Programming in Haskell

NASA Astrophysics Data System (ADS)

Peyton Jones, Simon; Singh, Satnam

This practical tutorial introduces the features available in Haskell for writing parallel and concurrent programs. We first describe how to write semi-explicit parallel programs by using annotations to express opportunities for parallelism and to help control the granularity of parallelism for effective execution on modern operating systems and processors. We then describe the mechanisms provided by Haskell for writing explicitly parallel programs with a focus on the use of software transactional memory to help share information between threads. Finally, we show how nested data parallelism can be used to write deterministically parallel programs which allows programmers to use rich data types in data parallel programs which are automatically transformed into flat data parallel versions for efficient execution on multi-core processors.

The engineering design integration (EDIN) system. [digital computer program complex

NASA Technical Reports Server (NTRS)

Glatt, C. R.; Hirsch, G. N.; Alford, G. E.; Colquitt, W. N.; Reiners, S. J.

1974-01-01

A digital computer program complex for the evaluation of aerospace vehicle preliminary designs is described. The system consists of a Univac 1100 series computer and peripherals using the Exec 8 operating system, a set of demand access terminals of the alphanumeric and graphics types, and a library of independent computer programs. Modification of the partial run streams, data base maintenance and construction, and control of program sequencing are provided by a data manipulation program called the DLG processor. The executive control of library program execution is performed by the Univac Exec 8 operating system through a user established run stream. A combination of demand and batch operations is employed in the evaluation of preliminary designs. Applications accomplished with the EDIN system are described.

Specification and Error Pattern Based Program Monitoring

NASA Technical Reports Server (NTRS)

Havelund, Klaus; Johnson, Scott; Rosu, Grigore; Clancy, Daniel (Technical Monitor)

2001-01-01

We briefly present Java PathExplorer (JPAX), a tool developed at NASA Ames for monitoring the execution of Java programs. JPAX can be used not only during program testing to reveal subtle errors, but also can be applied during operation to survey safety critical systems. The tool facilitates automated instrumentation of a program in order to properly observe its execution. The instrumentation can be either at the bytecode level or at the source level when the source code is available. JPaX is an instance of a more general project, called PathExplorer (PAX), which is a basis for experiments rather than a fixed system, capable of monitoring various programming languages and experimenting with other logics and analysis techniques

Generation of Non-Homogeneous Poisson Processes by Thinning: Programming Considerations and Comparision with Competing Algorithms.

DTIC Science & Technology

1978-12-01

Poisson processes . The method is valid for Poisson processes with any given intensity function. The basic thinning algorithm is modified to exploit several refinements which reduce computer execution time by approximately one-third. The basic and modified thinning programs are compared with the Poisson decomposition and gap-statistics algorithm, which is easily implemented for Poisson processes with intensity functions of the form exp(a sub 0 + a sub 1t + a sub 2 t-squared. The thinning programs are competitive in both execution

Synthesizing Dynamic Programming Algorithms from Linear Temporal Logic Formulae

NASA Technical Reports Server (NTRS)

Rosu, Grigore; Havelund, Klaus

2001-01-01

The problem of testing a linear temporal logic (LTL) formula on a finite execution trace of events, generated by an executing program, occurs naturally in runtime analysis of software. We present an algorithm which takes an LTL formula and generates an efficient dynamic programming algorithm. The generated algorithm tests whether the LTL formula is satisfied by a finite trace of events given as input. The generated algorithm runs in linear time, its constant depending on the size of the LTL formula. The memory needed is constant, also depending on the size of the formula.

Backtracking and Re-execution in the Automatic Debugging of Parallelized Programs

NASA Technical Reports Server (NTRS)

Matthews, Gregory; Hood, Robert; Johnson, Stephen; Leggett, Peter; Biegel, Bryan (Technical Monitor)

2002-01-01

In this work we describe a new approach using relative debugging to find differences in computation between a serial program and a parallel version of th it program. We use a combination of re-execution and backtracking in order to find the first difference in computation that may ultimately lead to an incorrect value that the user has indicated. In our prototype implementation we use static analysis information from a parallelization tool in order to perform the backtracking as well as the mapping required between serial and parallel computations.

A Study of the Extent and Effect of English Language Training for Refugees. Phase One: Results of a Comprehensive Mail Survey. Executive Summary.

ERIC Educational Resources Information Center

Northwest Regional Educational Lab., Portland, OR. Office of Research and Evaluation Services.

Results of a national survey of regional, state, and local agencies administering English language training programs for refugees, the first phase of a larger study of the training programs, are reported. The executive summary outlines the responses from 8 regional, 36 state, and 232 local agencies on four topics: (1) the nature and extent of…

Representation and Analysis of Real-Time Control Structures.

DTIC Science & Technology

1980-08-01

external processes which cannot be forced to cooperate with programmed processes through use of a synchronization primitive such as a semaphore [Dijkstre...amounts to each task, but the time slices are synchronized with program execution. The length of the codestrip is determined by the response time...which might be synchronous or asynchronous with respect to the executing task. The notation can represent total and partial orderings among its tasks, and

Programming in HAL/S

NASA Technical Reports Server (NTRS)

Ryer, M. J.

1978-01-01

HAL/S is a computer programming language; it is a representation for algorithms which can be interpreted by either a person or a computer. HAL/S compilers transform blocks of HAL/S code into machine language which can then be directly executed by a computer. When the machine language is executed, the algorithm specified by the HAL/S code (source) is performed. This document describes how to read and write HAL/S source.

Method and Process for the Creation of Modeling and Simulation Tools for Human Crowd Behavior

DTIC Science & Technology

2014-07-23

Support• Program Executive Office Ground Combat Systems • Program Executive Office Soldier TACOM LCMC MG Michael J. Terry Assigned/Direct Support...environmental technologies and explosive ordnance disposal Fire Control: Battlefield digitization; embedded system software; aero ballistics and...MRAD – Handheld stand-off NLW operated by Control Force • Simulated Projectile Weapon • Simulated Handheld Directed Energy NLW ( VDE ) – Simulated

The leadership/management role: a differentiating factor for ADN/BSN programs?

PubMed

Schank, M J; Stollenwerk, R

1988-06-01

The resurgence of the ADN/BSN issue relative to educational preparation and roles and the concomitant development of positions taken by the professional associations and National Commission on Nursing pointed to the need for study of current ADN/BSN curricula and utilization of graduates. Based upon a brief historical literature review and ADN/BSN competency statements, the leadership/management role was selected for study as a possible differentiating factor between these programs. Findings from a statewide study of ADN and BSN programs and a representative sample of nurse executives indicated that an education and service dilemma exists relative to this role. The majority of ADN program directors noted that a leadership/management component should be part of ADN curricula, whereas BSN program directors did not concur. Nurse executives utilized ADN graduates in leadership/management positions and stated that length of experience was an influencing factor in selection. Numerous other findings showed a discrepancy in beliefs and practices among educators and nurse executives. This survey demonstrates the need for curriculum changes and role clarification. The leadership/management role may be a viable area for consideration.

FX-87 performance measurements: data-flow implementation. Technical report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hammel, R.T.; Gifford, D.K.

1988-11-01

This report documents a series of experiments performed to explore the thesis that the FX-87 effect system permits a compiler to schedule imperative programs (i.e., programs that may contain side-effects) for execution on a parallel computer. The authors analyze how much the FX-87 static effect system can improve the execution times of five benchmark programs on a parallel graph interpreter. Three of their benchmark programs do not use side-effects (factorial, fibonacci, and polynomial division) and thus did not have any effect-induced constraints. Their FX-87 performance was comparable to their performance in a purely functional language. Two of the benchmark programsmore » use side effects (DNA sequence matching and Scheme interpretation) and the compiler was able to use effect information to reduce their execution times by factors of 1.7 to 5.4 when compared with sequential execution times. These results support the thesis that a static effect system is a powerful tool for compilation to multiprocessor computers. However, the graph interpreter we used was based on unrealistic assumptions, and thus our results may not accurately reflect the performance of a practical FX-87 implementation. The results also suggest that conventional loop analysis would complement the FX-87 effect system« less

Gravisensitivity of various host plant -virus systems in simulated microgravity

NASA Astrophysics Data System (ADS)

Mishchenko, Lidiya; Taran, Oksana; Gordejchyk, Olga

In spite of considerable achievements in the study of gravity effects on plant development, some issues of gravitropism, like species-specificity and gravitation response remain unclear. The so-lution of such problems is connected with the aspects of life supply, in piloted space expeditions. The role of microgravity remains practically unstudied in the development of relations in the system host plant-virus, which are important for biotechnologies in crop production. It is ev-ident that the conditions of space flight can act as stressors, and the stress inducted by them favors the reactivation of latest herpes viruses in humans (satish et al., 2009) Viral infections of plants, which also can be in a latest state at certain stages of plant organism development, cause great damage to the growth and development of a host plant. Space flight conditions may cause both reactivation of latent viral infection in plants and its elimination, as it has been found by us for the system WSMW -wheat (Mishchenko et al., 2004). Our further research activities were concentrated on the identification of gravisensitivity in the system virus -potato plant to find out whether there was any species -related specificity of the reaction. In our research we used potato plants of Krymska Rosa, Zhuravushka, Agave, Belarosa, Kupalinka, and Zdubytok varieties. Simulated microgravity was ensured by clinostats KG-8 and Cycle -2. Gravisensitiv-ity has been studied the systems including PVX, PVM and PVY. Virus concentrations have been determined by ELISA using LOEWE reagents (placecountry-regionGermany). Virus iden-tification by morphological features were done by electron microscopy. For the system PVX -potato plant, we found the reduction in virus antigens content with prolonged clinostating. On the 18th day of cultivation, the plants showed a high level of X-virus antigen content on both stationary (control) and clinostated variants. On 36th and 47th day, depending plant variety, clinostated plants had lower X-virus antigen content, compared with negative control. In plants, cultivated without clinostating, PVX antigen content was 5-10 times greater than on negative control variants. Prolonged (over 43 days) clinostating, depending on potato plant genotype, may cause both simulation and impeding of the accumulation of Y-virus antigens in potato plants. Studying the interaction between the host plant and PVM, we found that prolonged clinorotation at first reduced the antigen content by 25-30% compared with stationary control. Further on after 44 days of experimentation, the antigen content increased with more intensive increase in non-clinostated plants. Thus, prolonged clinostating reduced the intensity of anti-gen accumulation but did not stop it completely. We admit that proves a low sensitivity of the system PVM -potato plant to simulated microgravity. The phenomena of PVX reproduction in simulated microgravity may find on employment in present-day biotechnologies.

Program Instrumentation and Trace Analysis

NASA Technical Reports Server (NTRS)

Havelund, Klaus; Goldberg, Allen; Filman, Robert; Rosu, Grigore; Koga, Dennis (Technical Monitor)

2002-01-01

Several attempts have been made recently to apply techniques such as model checking and theorem proving to the analysis of programs. This shall be seen as a current trend to analyze real software systems instead of just their designs. This includes our own effort to develop a model checker for Java, the Java PathFinder 1, one of the very first of its kind in 1998. However, model checking cannot handle very large programs without some kind of abstraction of the program. This paper describes a complementary scalable technique to handle such large programs. Our interest is turned on the observation part of the equation: How much information can be extracted about a program from observing a single execution trace? It is our intention to develop a technology that can be applied automatically and to large full-size applications, with minimal modification to the code. We present a tool, Java PathExplorer (JPaX), for exploring execution traces of Java programs. The tool prioritizes scalability for completeness, and is directed towards detecting errors in programs, not to prove correctness. One core element in JPaX is an instrumentation package that allows to instrument Java byte code files to log various events when executed. The instrumentation is driven by a user provided script that specifies what information to log. Examples of instructions that such a script can contain are: 'report name and arguments of all called methods defined in class C, together with a timestamp'; 'report all updates to all variables'; and 'report all acquisitions and releases of locks'. In more complex instructions one can specify that certain expressions should be evaluated and even that certain code should be executed under various conditions. The instrumentation package can hence be seen as implementing Aspect Oriented Programming for Java in the sense that one can add functionality to a Java program without explicitly changing the code of the original program, but one rather writes an aspect and compiles it into the original program using the instrumentation. Another core element of JPaX is an observation package that supports the analysis of the generated event stream. Two kinds of analysis are currently supported. In temporal analysis the execution trace is evaluated against formulae written in temporal logic. We have implemented a temporal logic evaluator on finite traces using the Maude rewriting system from SRI International, USA. Temporal logic is defined in Maude by giving its syntax as a signature and its semantics as rewrite equations. The resulting semantics is extremely efficient and can handle event streams of hundreds of millions events in few minutes. Furthermore, the implementation is very succinct. The second form of even stream analysis supported is error pattern analysis where an execution trace is analyzed using various error detection algorithms that can identify error-prone programming practices that may potentially lead to errors in some different executions. Two such algorithms focusing on concurrency errors have been implemented in JPaX, one for deadlocks and the other for data races. It is important to note, that a deadlock or data race potential does not need to occur in order for its potential to be detected with these algorithms. This is what makes them very scalable in practice. The data race algorithm implemented is the Eraser algorithm from Compaq, however adopted to Java. The tool is currently being applied to a code base for controlling a spacecraft by the developers of that software in order to evaluate its applicability.

41 CFR 102-79.10 - What basic assignment and utilization of space policy governs an Executive agency?

Code of Federal Regulations, 2010 CFR

2010-07-01

... must provide a quality workplace environment that supports program operations, preserves the value of... fitness facilities in the workplace when adequately justified. An Executive agency must promote maximum...

Flight Design System-1 System Design Document. Volume 9: Executive logic flow, program design language

NASA Technical Reports Server (NTRS)

1979-01-01

The detailed logic flow for the Flight Design System Executive is presented. The system is designed to provide the hardware/software capability required for operational support of shuttle flight planning.

Executive Order 13045: Protection of Children from Environmental Health Risks and Safety Risks

EPA Pesticide Factsheets

President William Jefferson Clinton's Executive Order that each Federal agency assess safety risks to children; and ensure that policies, programs, activities, and standards address disproportionate risks. Also established the Task Force.

An expert system executive for automated assembly of large space truss structures

NASA Technical Reports Server (NTRS)

Allen, Cheryl L.

1993-01-01

Langley Research Center developed a unique test bed for investigating the practical problems associated with the assembly of large space truss structures using robotic manipulators. The test bed is the result of an interdisciplinary effort that encompasses the full spectrum of assembly problems - from the design of mechanisms to the development of software. The automated structures assembly test bed and its operation are described, the expert system executive and its development are detailed, and the planned system evolution is discussed. Emphasis is on the expert system implementation of the program executive. The executive program must direct and reliably perform complex assembly tasks with the flexibility to recover from realistic system errors. The employment of an expert system permits information that pertains to the operation of the system to be encapsulated concisely within a knowledge base. This consolidation substantially reduced code, increased flexibility, eased software upgrades, and realized a savings in software maintenance costs.

Java PathExplorer: A Runtime Verification Tool

NASA Technical Reports Server (NTRS)

Havelund, Klaus; Rosu, Grigore; Clancy, Daniel (Technical Monitor)

2001-01-01

We describe recent work on designing an environment called Java PathExplorer for monitoring the execution of Java programs. This environment facilitates the testing of execution traces against high level specifications, including temporal logic formulae. In addition, it contains algorithms for detecting classical error patterns in concurrent programs, such as deadlocks and data races. An initial prototype of the tool has been applied to the executive module of the planetary Rover K9, developed at NASA Ames. In this paper we describe the background and motivation for the development of this tool, including comments on how it relates to formal methods tools as well as to traditional testing, and we then present the tool itself.

Speech-language pathology telehealth in rural and remote schools: the experience of school executive and therapy assistants.

PubMed

Fairweather, Glenn C; Lincoln, Michelle A; Ramsden, Robyn

2017-01-01

Difficulties in accessing allied health services, especially in rural and remote areas, appear to be driving the use of telehealth services to children in schools. The objectives of this study were to investigate the experiences and views of school executive staff and therapy assistants regarding the feasibility and acceptability of a speech-language pathology telehealth program for children attending schools in rural and remote New South Wales, Australia. The program, called Come N See, provided therapy interventions remotely via low-bandwidth videoconferencing, with email follow-up. Over a 12-week period, children were offered therapy blocks of six fortnightly sessions, each lasting a maximum of 30 minutes. School executives (n=5) and therapy assistants (n=6) described factors that promoted or threatened the program's feasibility and acceptability, during semistructured interviews. Thematic content analysis with constant comparison was applied to the transcribed interviews to identify relationships in the data. Emergent themes related to (a) unmet speech pathology needs, (b) building relationships, (c) telehealth's advantages, (d) telehealth's disadvantages, (e) anxiety replaced by joy and confidence in growing skills, and (f) supports. School executive staff and therapy assistants verified that the delivery of the school-based telehealth service was feasible and acceptable. However, the participants saw significant opportunities to enhance this acceptability through building into the program stronger working relationships and supports for stakeholders. These findings are important for the future development of allied health telehealth programs that are sustainable as well as effective and fit the needs of all crucial stakeholders. The results have significant implications for speech pathology clinical practice relating to technology, program planning and teamwork within telehealth programs.

Principles of Faithful Execution in the implementation of trusted objects.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tarman, Thomas David; Campbell, Philip LaRoche; Pierson, Lyndon George

2003-09-01

We begin with the following definitions: Definition: A trusted volume is the computing machinery (including communication lines) within which data is assumed to be physically protected from an adversary. A trusted volume provides both integrity and privacy. Definition: Program integrity consists of the protection necessary to enable the detection of changes in the bits comprising a program as specified by the developer, for the entire time that the program is outside a trusted volume. For ease of discussion we consider program integrity to be the aggregation of two elements: instruction integrity (detection of changes in the bits within an instructionmore » or block of instructions), and sequence integrity (detection of changes in the locations of instructions within a program). Definition: Faithful Execution (FE) is a type of software protection that begins when the software leaves the control of the developer and ends within the trusted volume of a target processor. That is, FE provides program integrity, even while the program is in execution. (As we will show below, FE schemes are a function of trusted volume size.) FE is a necessary quality for computing. Without it we cannot trust computations. In the early days of computing FE came for free since the software never left a trusted volume. At that time the execution environment was the same as the development environment. In some circles that environment was referred to as a ''closed shop:'' all of the software that was used there was developed there. When an organization bought a large computer from a vendor the organization would run its own operating system on that computer, use only its own editors, only its own compilers, only its own debuggers, and so on. However, with the continuing maturity of computing technology, FE becomes increasingly difficult to achieve« less

Program Manager Assessments: Professionalism Personified

DTIC Science & Technology

2015-08-01

dozens of legacy systems. A few years ago, the idea of modernizing this collection in a “ big bang ” approach was rejected in favor of a lower-risk and...chain of com- mand. The assessments are simul - taneously sent to me, the Service or Component acquisition executive, and the program executive officer...use of actual test results at sub-scale, com- ponent testing, modeling, simulation , and field testing were all described in fair detail. Key near

LANL: Weapons Infrastructure Briefing to Naval Reactors, July 18, 2017

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chadwick, Frances

Presentation slides address: The Laboratory infrastructure supports hundreds of high hazard, complex operations daily; LANL’s unique science and engineering infrastructure is critical to delivering on our mission; LANL FY17 Budget & Workforce; Direct-Funded Infrastructure Accounts; LANL Org Chart; Weapons Infrastructure Program Office; The Laboratory’s infrastructure relies on both Direct and Indirect funding; NA-50’s Operating, Maintenance & Recapitalization funding is critical to the execution of the mission; Los Alamos is currently executing several concurrent Line Item projects; Maintenance @ LANL; NA-50 is helping us to address D&D needs; We are executing a CHAMP Pilot Project at LANL; G2 = Main Toolmore » for Program Management; MDI: Future Investments are centered on facilities with a high Mission Dependency Index; Los Alamos hosted first “Deep Dive” in November 2016; Safety, Infrastructure & Operations is one of the most important programs at LANL, and is foundational for our mission success.« less

Method for distributed object communications based on dynamically acquired and assembled software components

NASA Technical Reports Server (NTRS)

Sundermier, Amy (Inventor)

2002-01-01

A method for acquiring and assembling software components at execution time into a client program, where the components may be acquired from remote networked servers is disclosed. The acquired components are assembled according to knowledge represented within one or more acquired mediating components. A mediating component implements knowledge of an object model. A mediating component uses its implemented object model knowledge, acquired component class information and polymorphism to assemble components into an interacting program at execution time. The interactions or abstract relationships between components in the object model may be implemented by the mediating component as direct invocations or indirect events or software bus exchanges. The acquired components may establish communications with remote servers. The acquired components may also present a user interface representing data to be exchanged with the remote servers. The mediating components may be assembled into layers, allowing arbitrarily complex programs to be constructed at execution time.

Diffusion and utilization of scientific and technological knowledge within state and local governments: Executive summary

NASA Technical Reports Server (NTRS)

Feller, I.; Flanary, P. E.

1979-01-01

The requirements for technology transfer among the state and local governments are analyzed. Topics discussed include: information systems, federal funding, delivery channels, state executive programs, and state legislature requirements for scientific information.

GO, an exec for running the programs: CELL, COLLIDER, MAGIC, PATRICIA, PETROS, TRANSPORT, and TURTLE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shoaee, H.

1982-05-01

An exec has been written and placed on the PEP group's public disk to facilitate the use of several PEP related computer programs available on VM. The exec's program list currently includes: CELL, COLLIDER, MAGIC, PATRICIA, PETROS, TRANSPORT, and TURTLE. In addition, provisions have been made to allow addition of new programs to this list as they become available. The GO exec is directly callable from inside the Wylbur editor (in fact, currently this is the only way to use the GO exec.). It provides the option of running any of the above programs in either interactive or batch mode.more » In the batch mode, the GO exec sends the data in the Wylbur active file along with the information required to run the job to the batch monitor (BMON, a virtual machine that schedules and controls execution of batch jobs). This enables the user to proceed with other VM activities at his/her terminal while the job executes, thus making it of particular interest to the users with jobs requiring much CPU time to execute and/or those wishing to run multiple jobs independently. In the interactive mode, useful for small jobs requiring less CPU time, the job is executed by the user's own Virtual Machine using the data in the active file as input. At the termination of an interactive job, the GO exec facilitates examination of the output by placing it in the Wylbur active file.« less

GO, an exec for running the programs: CELL, COLLIDER, MAGIC, PATRICIA, PETROS, TRANSPORT and TURTLE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shoaee, H.

1982-05-01

An exec has been written and placed on the PEP group's public disk (PUBRL 192) to facilitate the use of several PEP related computer programs available on VM. The exec's program list currently includes: CELL, COLLIDER, MAGIC, PATRICIA, PETROS, TRANSPORT, and TURTLE. In addition, provisions have been made to allow addition of new programs to this list as they become available. The GO exec is directly callable from inside the Wylbur editor (in fact, currently this is the only way to use the GO exec.) It provides the option of running any of the above programs in either interactive ormore » batch mode. In the batch mode, the GO exec sends the data in the Wylbur active file along with the information required to run the job to the batch monitor (BMON, a virtual machine that schedules and controls execution of batch jobs). This enables the user to proceed with other VM activities at his/her terminal while the job executes, thus making it of particular interest to the users with jobs requiring much CPU time to execute and/or those wishing to run multiple jobs independently. In the interactive mode, useful for small jobs requiring less CPU time, the job is executed by the user's own Virtual Machine using the data in the active file as input. At the termination of an interactive job, the GO exec facilitates examination of the output by placing it in the Wylbur active file.« less

Structured Design Language for Computer Programs

NASA Technical Reports Server (NTRS)

Pace, Walter H., Jr.

1986-01-01

Box language used at all stages of program development. Developed to provide improved productivity in designing, coding, and maintaining computer programs. BOX system written in FORTRAN 77 for batch execution.

A modular finite-element model (MODFE) for areal and axisymmetric ground-water-flow problems, Part 3: Design philosophy and programming details

USGS Publications Warehouse

Torak, L.J.

1993-01-01

A MODular Finite-Element, digital-computer program (MODFE) was developed to simulate steady or unsteady-state, two-dimensional or axisymmetric ground-water-flow. The modular structure of MODFE places the computationally independent tasks that are performed routinely by digital-computer programs simulating ground-water flow into separate subroutines, which are executed from the main program by control statements. Each subroutine consists of complete sets of computations, or modules, which are identified by comment statements, and can be modified by the user without affecting unrelated computations elsewhere in the program. Simulation capabilities can be added or modified by either adding or modifying subroutines that perform specific computational tasks, and the modular-program structure allows the user to create versions of MODFE that contain only the simulation capabilities that pertain to the ground-water problem of interest. MODFE is written in a Fortran programming language that makes it virtually device independent and compatible with desk-top personal computers and large mainframes. MODFE uses computer storage and execution time efficiently by taking advantage of symmetry and sparseness within the coefficient matrices of the finite-element equations. Parts of the matrix coefficients are computed and stored as single-subscripted variables, which are assembled into a complete coefficient just prior to solution. Computer storage is reused during simulation to decrease storage requirements. Descriptions of subroutines that execute the computational steps of the modular-program structure are given in tables that cross reference the subroutines with particular versions of MODFE. Programming details of linear and nonlinear hydrologic terms are provided. Structure diagrams for the main programs show the order in which subroutines are executed for each version and illustrate some of the linear and nonlinear versions of MODFE that are possible. Computational aspects of changing stresses and boundary conditions with time and of mass-balance and error terms are given for each hydrologic feature. Program variables are listed and defined according to their occurrence in the main programs and in subroutines. Listings of the main programs and subroutines are given.

Spaceborne computer executive routine functional design specification. Volume 1: Functional design of a flight computer executive program for the reusable shuttle

NASA Technical Reports Server (NTRS)

Curran, R. T.

1971-01-01

A flight computer functional executive design for the reusable shuttle is presented. The design is given in the form of functional flowcharts and prose description. Techniques utilized in the regulation of process flow to accomplish activation, resource allocation, suspension, termination, and error masking based on process primitives are considered. Preliminary estimates of main storage utilization by the Executive are furnished. Conclusions and recommendations for timely, effective software-hardware integration in the reusable shuttle avionics system are proposed.

Traditional versus rule-based programming techniques - Application to the control of optional flight information

NASA Technical Reports Server (NTRS)

Ricks, Wendell R.; Abbott, Kathy H.

1987-01-01

A traditional programming technique for controlling the display of optional flight information in a civil transport cockpit is compared to a rule-based technique for the same function. This application required complex decision logic and a frequently modified rule base. The techniques are evaluated for execution efficiency and implementation ease; the criterion used to calculate the execution efficiency is the total number of steps required to isolate hypotheses that were true and the criteria used to evaluate the implementability are ease of modification and verification and explanation capability. It is observed that the traditional program is more efficient than the rule-based program; however, the rule-based programming technique is more applicable for improving programmer productivity.

Dynamic Optimization

NASA Technical Reports Server (NTRS)

Laird, Philip

1992-01-01

We distinguish static and dynamic optimization of programs: whereas static optimization modifies a program before runtime and is based only on its syntactical structure, dynamic optimization is based on the statistical properties of the input source and examples of program execution. Explanation-based generalization is a commonly used dynamic optimization method, but its effectiveness as a speedup-learning method is limited, in part because it fails to separate the learning process from the program transformation process. This paper describes a dynamic optimization technique called a learn-optimize cycle that first uses a learning element to uncover predictable patterns in the program execution and then uses an optimization algorithm to map these patterns into beneficial transformations. The technique has been used successfully for dynamic optimization of pure Prolog.

NASA Tech Briefs, January 2006

NASA Technical Reports Server (NTRS)

2006-01-01

Topics covered include: Semiautonomous Avionics-and-Sensors System for a UAV; Biomimetic/Optical Sensors for Detecting Bacterial Species; System Would Detect Foreign-Object Damage in Turbofan Engine; Detection of Water Hazards for Autonomous Robotic Vehicles; Fuel Cells Utilizing Oxygen From Air at Low Pressures; Hybrid Ion-Detector/Data-Acquisition System for a TOF-MS; Spontaneous-Desorption Ionizer for a TOF-MS; Equipment for On-Wafer Testing From 220 to 325 GHz; Computing Isentropic Flow Properties of Air/R-134a Mixtures; Java Mission Evaluation Workstation System; Using a Quadtree Algorithm To Assess Line of Sight; Software for Automated Generation of Cartesian Meshes; Optics Program Modified for Multithreaded Parallel Computing; Programs for Testing Processor-in-Memory Computing Systems; PVM Enhancement for Beowulf Multiple-Processor Nodes; Ion-Exclusion Chromatography for Analyzing Organics in Water; Selective Plasma Deposition of Fluorocarbon Films on SAMs; Water-Based Pressure-Sensitive Paints; System Finds Horizontal Location of Center of Gravity; Predicting Tail Buffet Loads of a Fighter Airplane; Water Containment Systems for Testing High-Speed Flywheels; Vapor-Compression Heat Pumps for Operation Aboard Spacecraft; Multistage Electrophoretic Separators; Recovering Residual Xenon Propellant for an Ion Propulsion System; Automated Solvent Seaming of Large Polyimide Membranes; Manufacturing Precise, Lightweight Paraboloidal Mirrors; Analysis of Membrane Lipids of Airborne Micro-Organisms; Noninvasive Diagnosis of Coronary Artery Disease Using 12-Lead High-Frequency Electrocardiograms; Dual-Laser-Pulse Ignition; Enhanced-Contrast Viewing of White-Hot Objects in Furnaces; Electrically Tunable Terahertz Quantum-Cascade Lasers; Few-Mode Whispering-Gallery-Mode Resonators; Conflict-Aware Scheduling Algorithm; and Real-Time Diagnosis of Faults Using a Bank of Kalman Filters.

Volunteer water monitoring: A guide for state managers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1990-08-01

Contents: executive summary; volunteers in water monitoring; planning a volunteer monitoring program; implementing a volunteer monitoring program; providing credible information; costs and funding; and descriptions of five successful programs.

MAGNA (Materially and Geometrically Nonlinear Analysis). Part I. Finite Element Analysis Manual.

DTIC Science & Technology

1982-12-01

provided for operating the program, modifying storage caoacity, preparing input data, estimating computer run times , and interpreting the output...7.1.3 Reserved File Names 7.1.16 7.1.4 Typical Execution Times on CDC Computers 7.1.18 7.2 CRAY PROGRAM VERSION 7.2.1 7.2.1 Job Control Language 7.2.1...7.2.2 Modification of Storage Capacity 7.2.8 7.2.3 Execution Times on the CRAY-I Computer 7.2.12 7.3 VAX PROGRAM VERSION 7.3.1 8 INPUT DATA 8.0.1 8.1

Executive control systems in the engineering design environment

NASA Technical Reports Server (NTRS)

Hurst, P. W.; Pratt, T. W.

1985-01-01

Executive Control Systems (ECSs) are software structures for the unification of various engineering design application programs into comprehensive systems with a central user interface (uniform access) method and a data management facility. Attention is presently given to the most significant determinations of a research program conducted for 24 ECSs, used in government and industry engineering design environments to integrate CAD/CAE applications programs. Characterizations are given for the systems' major architectural components and the alternative design approaches considered in their development. Attention is given to ECS development prospects in the areas of interdisciplinary usage, standardization, knowledge utilization, and computer science technology transfer.

Seismic vulnerability of new highway construction, executive summary.

DOT National Transportation Integrated Search

2002-03-01

This executive summary gives an overview of the results of FHWA Contract DTFH61-92-C-00112, Seismic Research Program, : which performed a series of special studies addressing the seismic design of new construction. The objectives of this project : we...

5 CFR 2638.403 - Agency compliance.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 3 2011-01-01 2011-01-01 false Agency compliance. 2638.403 Section 2638.403 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Correction of Executive Branch Agency Ethics...

Seismic Vulnerability of New Highway Construction, Executive Summary.

DOT National Transportation Integrated Search

2002-03-01

This executive summary gives an overview of the results of FHWA Contract DTFH61-92-C-00112, Seismic Research Program, which performed a series of special studies addressing the seismic design of new construction. The objectives of this project were t...

17 CFR 37.203 - Rule enforcement program.

Code of Federal Regulations, 2014 CFR

2014-04-01

... shall establish and enforce trading, trade processing, and participation rules that will deter abuses... practices prohibited. A swap execution facility shall prohibit abusive trading practices on its markets by members and market participants. Swap execution facilities that permit intermediation shall prohibit...

40 CFR 1.37 - Office of External Affairs.

Code of Federal Regulations, 2010 CFR

2010-07-01

... compliance with the National Environmental Policy Act (NEPA) and related laws, directives, and Executive policies concerning special environmental areas and cultural resources; (3) Compliance with Executive policy on American Indian affairs and the development of programs for environmental protection on Indian...

5 CFR 2638.403 - Agency compliance.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Agency compliance. 2638.403 Section 2638.403 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Correction of Executive Branch Agency Ethics...

5 CFR 1303.2 - Authority and functions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 1303.2 Administrative Personnel OFFICE OF MANAGEMENT AND BUDGET ADMINISTRATIVE PROCEDURES PUBLIC... general functions of the Office of Management and Budget, as provided by statute and executive order, are to develop and execute the budget, oversee implementation of Administration policies and programs...

5 CFR 2638.403 - Agency compliance.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 5 Administrative Personnel 3 2012-01-01 2012-01-01 false Agency compliance. 2638.403 Section 2638.403 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Correction of Executive Branch Agency Ethics...

5 CFR 2638.403 - Agency compliance.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 5 Administrative Personnel 3 2013-01-01 2013-01-01 false Agency compliance. 2638.403 Section 2638.403 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Correction of Executive Branch Agency Ethics...

5 CFR 2638.403 - Agency compliance.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 5 Administrative Personnel 3 2014-01-01 2014-01-01 false Agency compliance. 2638.403 Section 2638.403 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Correction of Executive Branch Agency Ethics...

2008 Munitions Executive Summit

DTIC Science & Technology

2008-02-21

7:00pm Hosted Reception 2008 Munitions Executive Summit February 20, 2008 – AGENDA (cont.) 8:00am Administrative Remarks 8:05am PEO Keynote Address...MES Awards Tuesday, February 19 5pm Reception /Pre-registration Sponsored by ATK Ammunition Systems Group and Kaman Aerospace’s Fuzing...15pm Adjourn 5:15pm - 7pm Hosted Reception Sponsored by DSE, Inc. and General Dynamics-OTS Munitions executive suMMit 2008 agenda & prograM

A distributed version of the NASA Engine Performance Program

NASA Technical Reports Server (NTRS)

Cours, Jeffrey T.; Curlett, Brian P.

1993-01-01

Distributed NEPP, a version of the NASA Engine Performance Program, uses the original NEPP code but executes it in a distributed computer environment. Multiple workstations connected by a network increase the program's speed and, more importantly, the complexity of the cases it can handle in a reasonable time. Distributed NEPP uses the public domain software package, called Parallel Virtual Machine, allowing it to execute on clusters of machines containing many different architectures. It includes the capability to link with other computers, allowing them to process NEPP jobs in parallel. This paper discusses the design issues and granularity considerations that entered into programming Distributed NEPP and presents the results of timing runs.

Global Forest Products Model software design and implementation (GFPM version 2014 with BPMP)

Treesearch

Shushuai Zhu; James Turner; Joseph   Buongiorno

2014-01-01

An overview of the GFPM software structure is given in Section 1.1 in terms of the overall processing flows and the main components of the GFPM. Section 1.2 describes the role of batch files in controlling the execution of the GFPM programs, and details of the sequence of program execution corresponding to each of the “Main Menu” options of the GFPM. Next, each...

A Report on the Navy SBIR Program: Best Practices, Roadblocks and Recommendations for Technology Transition

DTIC Science & Technology

2008-04-01

a recommendation to the Phase I Sponsor, the NAVSEA SBIR Program Manager, and the PCO between 90 and 180 days after Phase I contract execution...determine eligibility for Phase II and send recommendations to sponsor Between 90 and 180 days after contract execution PCO Invites Phase II Proposals...manning study to evaluate the claim of inadequate numbers of contracting personnel. Although there were symptoms that contract delays were in part

Software attribute visualization for high integrity software

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pollock, G.M.

1998-03-01

This report documents a prototype tool developed to investigate the use of visualization and virtual reality technologies for improving software surety confidence. The tool is utilized within the execution phase of the software life cycle. It provides a capability to monitor an executing program against prespecified requirements constraints provided in a program written in the requirements specification language SAGE. The resulting Software Attribute Visual Analysis Tool (SAVAnT) also provides a technique to assess the completeness of a software specification.

Nonlinear Fluid Computations in a Distributed Environment

NASA Technical Reports Server (NTRS)

Atwood, Christopher A.; Smith, Merritt H.

1995-01-01

The performance of a loosely and tightly-coupled workstation cluster is compared against a conventional vector supercomputer for the solution the Reynolds- averaged Navier-Stokes equations. The application geometries include a transonic airfoil, a tiltrotor wing/fuselage, and a wing/body/empennage/nacelle transport. Decomposition is of the manager-worker type, with solution of one grid zone per worker process coupled using the PVM message passing library. Task allocation is determined by grid size and processor speed, subject to available memory penalties. Each fluid zone is computed using an implicit diagonal scheme in an overset mesh framework, while relative body motion is accomplished using an additional worker process to re-establish grid communication.

An intelligent allocation algorithm for parallel processing

NASA Technical Reports Server (NTRS)

Carroll, Chester C.; Homaifar, Abdollah; Ananthram, Kishan G.

1988-01-01

The problem of allocating nodes of a program graph to processors in a parallel processing architecture is considered. The algorithm is based on critical path analysis, some allocation heuristics, and the execution granularity of nodes in a program graph. These factors, and the structure of interprocessor communication network, influence the allocation. To achieve realistic estimations of the executive durations of allocations, the algorithm considers the fact that nodes in a program graph have to communicate through varying numbers of tokens. Coarse and fine granularities have been implemented, with interprocessor token-communication duration, varying from zero up to values comparable to the execution durations of individual nodes. The effect on allocation of communication network structures is demonstrated by performing allocations for crossbar (non-blocking) and star (blocking) networks. The algorithm assumes the availability of as many processors as it needs for the optimal allocation of any program graph. Hence, the focus of allocation has been on varying token-communication durations rather than varying the number of processors. The algorithm always utilizes as many processors as necessary for the optimal allocation of any program graph, depending upon granularity and characteristics of the interprocessor communication network.

IAC-1.5 - INTEGRATED ANALYSIS CAPABILITY

NASA Technical Reports Server (NTRS)

Vos, R. G.

1994-01-01

The objective of the Integrated Analysis Capability (IAC) system is to provide a highly effective, interactive analysis tool for the integrated design of large structures. IAC was developed to interface programs from the fields of structures, thermodynamics, controls, and system dynamics with an executive system and a database to yield a highly efficient multi-disciplinary system. Special attention is given to user requirements such as data handling and on-line assistance with operational features, and the ability to add new modules of the user's choice at a future date. IAC contains an executive system, a database, general utilities, interfaces to various engineering programs, and a framework for building interfaces to other programs. IAC has shown itself to be effective in automating data transfer among analysis programs. The IAC system architecture is modular in design. 1) The executive module contains an input command processor, an extensive data management system, and driver code to execute the application modules. 2) Technical modules provide standalone computational capability as well as support for various solution paths or coupled analyses. 3) Graphics and model generation modules are supplied for building and viewing models. 4) Interface modules provide for the required data flow between IAC and other modules. 5) User modules can be arbitrary executable programs or JCL procedures with no pre-defined relationship to IAC. 6) Special purpose modules are included, such as MIMIC (Model Integration via Mesh Interpolation Coefficients), which transforms field values from one model to another; LINK, which simplifies incorporation of user specific modules into IAC modules; and DATAPAC, the National Bureau of Standards statistical analysis package. The IAC database contains structured files which provide a common basis for communication between modules and the executive system, and can contain unstructured files such as NASTRAN checkpoint files, DISCOS plot files, object code, etc. The user can define groups of data and relations between them. A full data manipulation and query system operates with the database. The current interface modules comprise five groups: 1) Structural analysis - IAC contains a NASTRAN interface for standalone analysis or certain structural/control/thermal combinations. IAC provides enhanced structural capabilities for normal modes and static deformation analysis via special DMAP sequences. 2) Thermal analysis - IAC supports finite element and finite difference techniques for steady state or transient analysis. There are interfaces for the NASTRAN thermal analyzer, SINDA/SINFLO, and TRASYS II. 3) System dynamics - A DISCOS interface allows full use of this simulation program for either nonlinear time domain analysis or linear frequency domain analysis. 4) Control analysis - Interfaces for the ORACLS, SAMSAN, NBOD2, and INCA programs allow a wide range of control system analyses and synthesis techniques. 5) Graphics - The graphics packages PLOT and MOSAIC are included in IAC. PLOT generates vector displays of tabular data in the form of curves, charts, correlation tables, etc., while MOSAIC generates color raster displays of either tabular of array type data. Either DI3000 or PLOT-10 graphics software is required for full graphics capability. IAC is available by license for a period of 10 years to approved licensees. The licensed program product includes one complete set of supporting documentation. Additional copies of the documentation may be purchased separately. IAC is written in FORTRAN 77 and has been implemented on a DEC VAX series computer operating under VMS. IAC can be executed by multiple concurrent users in batch or interactive mode. The basic central memory requirement is approximately 750KB. IAC includes the executive system, graphics modules, a database, general utilities, and the interfaces to all analysis and controls programs described above. Source code is provided for the control programs ORACLS, SAMSAN, NBOD2, and DISCOS. The following programs are also available from COSMIC a

IAC-1.5 - INTEGRATED ANALYSIS CAPABILITY

NASA Technical Reports Server (NTRS)

Vos, R. G.

1994-01-01

The objective of the Integrated Analysis Capability (IAC) system is to provide a highly effective, interactive analysis tool for the integrated design of large structures. IAC was developed to interface programs from the fields of structures, thermodynamics, controls, and system dynamics with an executive system and a database to yield a highly efficient multi-disciplinary system. Special attention is given to user requirements such as data handling and on-line assistance with operational features, and the ability to add new modules of the user's choice at a future date. IAC contains an executive system, a database, general utilities, interfaces to various engineering programs, and a framework for building interfaces to other programs. IAC has shown itself to be effective in automating data transfer among analysis programs. The IAC system architecture is modular in design. 1) The executive module contains an input command processor, an extensive data management system, and driver code to execute the application modules. 2) Technical modules provide standalone computational capability as well as support for various solution paths or coupled analyses. 3) Graphics and model generation modules are supplied for building and viewing models. 4) Interface modules provide for the required data flow between IAC and other modules. 5) User modules can be arbitrary executable programs or JCL procedures with no pre-defined relationship to IAC. 6) Special purpose modules are included, such as MIMIC (Model Integration via Mesh Interpolation Coefficients), which transforms field values from one model to another; LINK, which simplifies incorporation of user specific modules into IAC modules; and DATAPAC, the National Bureau of Standards statistical analysis package. The IAC database contains structured files which provide a common basis for communication between modules and the executive system, and can contain unstructured files such as NASTRAN checkpoint files, DISCOS plot files, object code, etc. The user can define groups of data and relations between them. A full data manipulation and query system operates with the database. The current interface modules comprise five groups: 1) Structural analysis - IAC contains a NASTRAN interface for standalone analysis or certain structural/control/thermal combinations. IAC provides enhanced structural capabilities for normal modes and static deformation analysis via special DMAP sequences. 2) Thermal analysis - IAC supports finite element and finite difference techniques for steady state or transient analysis. There are interfaces for the NASTRAN thermal analyzer, SINDA/SINFLO, and TRASYS II. 3) System dynamics - A DISCOS interface allows full use of this simulation program for either nonlinear time domain analysis or linear frequency domain analysis. 4) Control analysis - Interfaces for the ORACLS, SAMSAN, NBOD2, and INCA programs allow a wide range of control system analyses and synthesis techniques. 5) Graphics - The graphics packages PLOT and MOSAIC are included in IAC. PLOT generates vector displays of tabular data in the form of curves, charts, correlation tables, etc., while MOSAIC generates color raster displays of either tabular of array type data. Either DI3000 or PLOT-10 graphics software is required for full graphics capability. IAC is available by license for a period of 10 years to approved licensees. The licensed program product includes one complete set of supporting documentation. Additional copies of the documentation may be purchased separately. IAC is written in FORTRAN 77 and has been implemented on a DEC VAX series computer operating under VMS. IAC can be executed by multiple concurrent users in batch or interactive mode. The basic central memory requirement is approximately 750KB. IAC includes the executive system, graphics modules, a database, general utilities, and the interfaces to all analysis and controls programs described above. Source code is provided for the control programs ORACLS, SAMSAN, NBOD2, and DISCOS. The following programs are also available from COSMIC as separate packages: NASTRAN, SINDA/SINFLO, TRASYS II, DISCOS, ORACLS, SAMSAN, NBOD2, and INCA. IAC was developed in 1985.

NUL Youth Programs

ERIC Educational Resources Information Center

Cooper, Maudine Rice

1977-01-01

This article indicates some of the ways in which the National Urban League has dealt with the problem of minority youth. These ways include programs such as the Street Academy Program, student internship programs, and the Black Executive Exchange Program, a conference on youth employment, and affiliation with other programs. (Author/AM)

Real-time Java for flight applications: an update

NASA Technical Reports Server (NTRS)

Dvorak, D.

2003-01-01

The RTSJ is a specification for supporting real-time execution in the Java programming language. The specification has been shaped by several guiding principles, particularly: predictable execution as the first priority in all tradeoffs, no syntactic extensions to Java, and backward compatibility.

5 CFR 960.107 - Authorized activities.

Code of Federal Regulations, 2010 CFR

2010-01-01

... coordinated approaches to the development and operation of programs that have common characteristics; (3) communicate management initiatives and other concerns from Washington to the field to achieve better mutual... serve as an instrument of outreach for the national headquarters of the Executive Branch to Executive...

5 CFR 960.107 - Authorized activities.

Code of Federal Regulations, 2011 CFR

2011-01-01

... coordinated approaches to the development and operation of programs that have common characteristics; (3) communicate management initiatives and other concerns from Washington to the field to achieve better mutual... serve as an instrument of outreach for the national headquarters of the Executive Branch to Executive...

5 CFR 2638.404 - Report of noncompliance.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 3 2011-01-01 2011-01-01 false Report of noncompliance. 2638.404 Section 2638.404 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Correction of Executive Branch Agency Ethics...

5 CFR 2638.404 - Report of noncompliance.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Report of noncompliance. 2638.404 Section 2638.404 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Correction of Executive Branch Agency Ethics...

78 FR 70012 - Submission for OMB Review; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-22

..., Office of Management and Budget (OMB), New Executive Office Building, Washington, DC; New Executive... a currently valid OMB control number. Agricultural Marketing Service Title: National Organic Program... marketing of certain agricultural products as organically produced products; (2) to assure consumers that...

Turtlegraphics: A Comparison of Logo and Turbo Pascal.

ERIC Educational Resources Information Center

VanLengen, Craig A.

1989-01-01

The integrated compiler of the Turbo Pascal environment allows the execution of a completed program independent of the developed environment and with greater execution speed, in comparison with LOGO. Conversion table of turtle-graphic commands for the two languages is presented. (Author/YP)

Instrumentation, performance visualization, and debugging tools for multiprocessors

NASA Technical Reports Server (NTRS)

Yan, Jerry C.; Fineman, Charles E.; Hontalas, Philip J.

1991-01-01

The need for computing power has forced a migration from serial computation on a single processor to parallel processing on multiprocessor architectures. However, without effective means to monitor (and visualize) program execution, debugging, and tuning parallel programs becomes intractably difficult as program complexity increases with the number of processors. Research on performance evaluation tools for multiprocessors is being carried out at ARC. Besides investigating new techniques for instrumenting, monitoring, and presenting the state of parallel program execution in a coherent and user-friendly manner, prototypes of software tools are being incorporated into the run-time environments of various hardware testbeds to evaluate their impact on user productivity. Our current tool set, the Ames Instrumentation Systems (AIMS), incorporates features from various software systems developed in academia and industry. The execution of FORTRAN programs on the Intel iPSC/860 can be automatically instrumented and monitored. Performance data collected in this manner can be displayed graphically on workstations supporting X-Windows. We have successfully compared various parallel algorithms for computational fluid dynamics (CFD) applications in collaboration with scientists from the Numerical Aerodynamic Simulation Systems Division. By performing these comparisons, we show that performance monitors and debuggers such as AIMS are practical and can illuminate the complex dynamics that occur within parallel programs.

SAP- FORTRAN STATIC SOURCE CODE ANALYZER PROGRAM (IBM VERSION)

NASA Technical Reports Server (NTRS)

Manteufel, R.

1994-01-01

The FORTRAN Static Source Code Analyzer program, SAP, was developed to automatically gather statistics on the occurrences of statements and structures within a FORTRAN program and to provide for the reporting of those statistics. Provisions have been made for weighting each statistic and to provide an overall figure of complexity. Statistics, as well as figures of complexity, are gathered on a module by module basis. Overall summed statistics are also accumulated for the complete input source file. SAP accepts as input syntactically correct FORTRAN source code written in the FORTRAN 77 standard language. In addition, code written using features in the following languages is also accepted: VAX-11 FORTRAN, IBM S/360 FORTRAN IV Level H Extended; and Structured FORTRAN. The SAP program utilizes two external files in its analysis procedure. A keyword file allows flexibility in classifying statements and in marking a statement as either executable or non-executable. A statistical weight file allows the user to assign weights to all output statistics, thus allowing the user flexibility in defining the figure of complexity. The SAP program is written in FORTRAN IV for batch execution and has been implemented on a DEC VAX series computer under VMS and on an IBM 370 series computer under MVS. The SAP program was developed in 1978 and last updated in 1985.

SAP- FORTRAN STATIC SOURCE CODE ANALYZER PROGRAM (DEC VAX VERSION)

NASA Technical Reports Server (NTRS)

Merwarth, P. D.

1994-01-01

The FORTRAN Static Source Code Analyzer program, SAP, was developed to automatically gather statistics on the occurrences of statements and structures within a FORTRAN program and to provide for the reporting of those statistics. Provisions have been made for weighting each statistic and to provide an overall figure of complexity. Statistics, as well as figures of complexity, are gathered on a module by module basis. Overall summed statistics are also accumulated for the complete input source file. SAP accepts as input syntactically correct FORTRAN source code written in the FORTRAN 77 standard language. In addition, code written using features in the following languages is also accepted: VAX-11 FORTRAN, IBM S/360 FORTRAN IV Level H Extended; and Structured FORTRAN. The SAP program utilizes two external files in its analysis procedure. A keyword file allows flexibility in classifying statements and in marking a statement as either executable or non-executable. A statistical weight file allows the user to assign weights to all output statistics, thus allowing the user flexibility in defining the figure of complexity. The SAP program is written in FORTRAN IV for batch execution and has been implemented on a DEC VAX series computer under VMS and on an IBM 370 series computer under MVS. The SAP program was developed in 1978 and last updated in 1985.

Research on computer systems benchmarking

NASA Technical Reports Server (NTRS)

Smith, Alan Jay (Principal Investigator)

1996-01-01

This grant addresses the topic of research on computer systems benchmarking and is more generally concerned with performance issues in computer systems. This report reviews work in those areas during the period of NASA support under this grant. The bulk of the work performed concerned benchmarking and analysis of CPUs, compilers, caches, and benchmark programs. The first part of this work concerned the issue of benchmark performance prediction. A new approach to benchmarking and machine characterization was reported, using a machine characterizer that measures the performance of a given system in terms of a Fortran abstract machine. Another report focused on analyzing compiler performance. The performance impact of optimization in the context of our methodology for CPU performance characterization was based on the abstract machine model. Benchmark programs are analyzed in another paper. A machine-independent model of program execution was developed to characterize both machine performance and program execution. By merging these machine and program characterizations, execution time can be estimated for arbitrary machine/program combinations. The work was continued into the domain of parallel and vector machines, including the issue of caches in vector processors and multiprocessors. All of the afore-mentioned accomplishments are more specifically summarized in this report, as well as those smaller in magnitude supported by this grant.

A primer for biomedical scientists on how to execute model II linear regression analysis.

PubMed

Ludbrook, John

2012-04-01

1. There are two very different ways of executing linear regression analysis. One is Model I, when the x-values are fixed by the experimenter. The other is Model II, in which the x-values are free to vary and are subject to error. 2. I have received numerous complaints from biomedical scientists that they have great difficulty in executing Model II linear regression analysis. This may explain the results of a Google Scholar search, which showed that the authors of articles in journals of physiology, pharmacology and biochemistry rarely use Model II regression analysis. 3. I repeat my previous arguments in favour of using least products linear regression analysis for Model II regressions. I review three methods for executing ordinary least products (OLP) and weighted least products (WLP) regression analysis: (i) scientific calculator and/or computer spreadsheet; (ii) specific purpose computer programs; and (iii) general purpose computer programs. 4. Using a scientific calculator and/or computer spreadsheet, it is easy to obtain correct values for OLP slope and intercept, but the corresponding 95% confidence intervals (CI) are inaccurate. 5. Using specific purpose computer programs, the freeware computer program smatr gives the correct OLP regression coefficients and obtains 95% CI by bootstrapping. In addition, smatr can be used to compare the slopes of OLP lines. 6. When using general purpose computer programs, I recommend the commercial programs systat and Statistica for those who regularly undertake linear regression analysis and I give step-by-step instructions in the Supplementary Information as to how to use loss functions. © 2011 The Author. Clinical and Experimental Pharmacology and Physiology. © 2011 Blackwell Publishing Asia Pty Ltd.

Space industrialization. Volume 1: Executive summary

NASA Technical Reports Server (NTRS)

1978-01-01

Potential goals for space industrialization were identified, and evolutionary program options for the realization of those goals were developed and assessed. Program support demands were defined, and recommendations were made in relation to program implementation.

Strategies for Energy Efficient Resource Management of Hybrid Programming Models

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Dong; Supinski, Bronis de; Schulz, Martin

2013-01-01

Many scientific applications are programmed using hybrid programming models that use both message-passing and shared-memory, due to the increasing prevalence of large-scale systems with multicore, multisocket nodes. Previous work has shown that energy efficiency can be improved using software-controlled execution schemes that consider both the programming model and the power-aware execution capabilities of the system. However, such approaches have focused on identifying optimal resource utilization for one programming model, either shared-memory or message-passing, in isolation. The potential solution space, thus the challenge, increases substantially when optimizing hybrid models since the possible resource configurations increase exponentially. Nonetheless, with the accelerating adoptionmore » of hybrid programming models, we increasingly need improved energy efficiency in hybrid parallel applications on large-scale systems. In this work, we present new software-controlled execution schemes that consider the effects of dynamic concurrency throttling (DCT) and dynamic voltage and frequency scaling (DVFS) in the context of hybrid programming models. Specifically, we present predictive models and novel algorithms based on statistical analysis that anticipate application power and time requirements under different concurrency and frequency configurations. We apply our models and methods to the NPB MZ benchmarks and selected applications from the ASC Sequoia codes. Overall, we achieve substantial energy savings (8.74% on average and up to 13.8%) with some performance gain (up to 7.5%) or negligible performance loss.« less

Fracture Mechanics Analysis of Single and Double Rows of Fastener Holes Loaded in Bearing

DTIC Science & Technology

1976-04-01

the following subprograms for execution: 1. ASRL FEABL-2 subroutines ASMLTV, ASMSUB, BCON, FACT, ORK, QBACK, SETUP, SIMULQ, STACON, and XTRACT. 2. IBM ...based on program code generated by IBM FORTRAN-G1 and FORTRAN-H compilers, with demonstration runs made on an IBM 370/168 computer. Programs SROW and...DROW are supplied ready to execute on systems with IBM -standard FORTRAN unit members for the card reader (unit 5) and line printer (unit 6). The

Multiscale Issues and Simulation-Based Science and Engineering for Materials-by-Design

DTIC Science & Technology

2010-05-15

planning and execution of programs to achieve the vision of ? material -by-design?. A key part of this effort has been to examine modeling at the mesoscale...15. SUBJECT TERMS Modelling & Simulation, Materials Design 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT Same as Report (SAR) 18...planning and execution of programs to achieve the vision of “ material -by-design”. A key part of this effort has been to examine modeling at the mesoscale. A

78 FR 69433 - Executive Order 13650 Improving Chemical Facility Safety and Security Listening Sessions

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-19

... Chemical Facility Safety and Security Listening Sessions AGENCY: National Protection and Programs... from stakeholders on issues pertaining to Improving Chemical Facility Safety and Security (Executive... regulations, guidance, and policies; and identifying best practices in chemical facility safety and security...

5 CFR 2638.705 - Annual ethics training for other employees.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 3 2011-01-01 2011-01-01 false Annual ethics training for other employees. 2638.705 Section 2638.705 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Executive Agency Ethics...

5 CFR 2638.704 - Annual ethics training for public filers.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 3 2011-01-01 2011-01-01 false Annual ethics training for public filers. 2638.704 Section 2638.704 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Executive Agency Ethics...

The President's Environmental Program, 1977.

ERIC Educational Resources Information Center

Council on Environmental Quality, Washington, DC.

This government publication contains, in the order given, President Carter's Message on the Environment; a Fact Sheet explaining the background and details of the President's proposed legislation, Executive orders, and directives; the Executive orders themselves; and a brief explanation of the Administration position on the Clean Air Act…

5 CFR 2638.705 - Annual ethics training for other employees.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Annual ethics training for other employees. 2638.705 Section 2638.705 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Executive Agency Ethics...

5 CFR 2638.704 - Annual ethics training for public filers.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Annual ethics training for public filers. 2638.704 Section 2638.704 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Executive Agency Ethics...

5 CFR 2638.704 - Annual ethics training for public filers.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 5 Administrative Personnel 3 2013-01-01 2013-01-01 false Annual ethics training for public filers. 2638.704 Section 2638.704 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Executive Agency Ethics...

5 CFR 2638.705 - Annual ethics training for other employees.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 5 Administrative Personnel 3 2012-01-01 2012-01-01 false Annual ethics training for other employees. 2638.705 Section 2638.705 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Executive Agency Ethics...

5 CFR 2638.705 - Annual ethics training for other employees.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 5 Administrative Personnel 3 2013-01-01 2013-01-01 false Annual ethics training for other employees. 2638.705 Section 2638.705 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Executive Agency Ethics...

5 CFR 2638.705 - Annual ethics training for other employees.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 5 Administrative Personnel 3 2014-01-01 2014-01-01 false Annual ethics training for other employees. 2638.705 Section 2638.705 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Executive Agency Ethics...

5 CFR 2638.704 - Annual ethics training for public filers.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 5 Administrative Personnel 3 2014-01-01 2014-01-01 false Annual ethics training for public filers. 2638.704 Section 2638.704 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Executive Agency Ethics...

5 CFR 2638.704 - Annual ethics training for public filers.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 5 Administrative Personnel 3 2012-01-01 2012-01-01 false Annual ethics training for public filers. 2638.704 Section 2638.704 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Executive Agency Ethics...

The Broad Superintendents Academy, 2007

ERIC Educational Resources Information Center

Broad Foundation, 2007

2007-01-01

The Broad Superintendents Academy is an executive training program that identifies and prepares prominent leaders--executives with experience successfully leading large organizations and a passion for public service--then places them in urban school districts to dramatically improve the quality of education for America's students. This brochure…

Data processing with microcode designed with source coding

DOEpatents

McCoy, James A; Morrison, Steven E

2013-05-07

Programming for a data processor to execute a data processing application is provided using microcode source code. The microcode source code is assembled to produce microcode that includes digital microcode instructions with which to signal the data processor to execute the data processing application.

Cost-Effective CNC Part Program Verification Development for Laboratory Instruction.

ERIC Educational Resources Information Center

Chen, Joseph C.; Chang, Ted C.

2000-01-01

Describes a computer numerical control program verification system that checks a part program before its execution. The system includes character recognition, word recognition, a fuzzy-nets system, and a tool path viewer. (SK)

Compendium of field operational test executive summaries

DOT National Transportation Integrated Search

1998-01-01

The Intelligent Transportation Systems Program is a comprehensive program aimed at applying advanced technologies to improve the safety and efficiency of our Nation's surface transportation system. The program is organized around four broad areas: me...

Some attributes of a language for property-based testing.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Neagoe, Vicentiu; Bishop, Matt

Property-based testing is a testing technique that evaluates executions of a program. The method checks that specifications, called properties, hold throughout the execution of the program. TASpec is a language used to specify these properties. This paper compares some attributes of the language with the specification patterns used for model-checking languages, and then presents some descriptions of properties that can be used to detect common security flaws in programs. This report describes the results of a one year research project at the University of California, Davis, which was funded by a University Collaboration LDRD entitled ''Property-based Testing for Cyber Securitymore » Assurance''.« less

Research and technology

NASA Technical Reports Server (NTRS)

1988-01-01

As the NASA Center responsible for assembly, checkout, servicing, launch, recovery and operational support of Space Transportation System elements and payloads, Kennedy Space Center is placing emphasis on its research and technology program. In addition to strengthening those areas of engineering and operations technology that contribute to safer, more efficient, and more economical execution of our current mission, we are developing the technological tools needed to execute the Center's mission relative to future programs. The Engineering Development Directorate encompasses most of the laboratories and other Center resources that are key elements of research and technology program implementation, and is responsible for implementation of the majority of the projects in this Kennedy Space Center 1988 Annual Report.

An evaluation of organic light emitting diode monitors for medical applications: Great timing, but luminance artifacts

PubMed Central

Elze, Tobias; Taylor, Christopher; Bex, Peter J.

2013-01-01

Purpose: In contrast to the dominant medical liquid crystal display (LCD) technology, organic light-emitting diode (OLED) monitors control the display luminance via separate light-emitting diodes for each pixel and are therefore supposed to overcome many previously documented temporal artifacts of medical LCDs. We assessed the temporal and luminance characteristics of the only currently available OLED monitor designed for use in the medical treatment field (SONY PVM2551MD) and checked the authors’ main findings with another SONY OLED device (PVM2541). Methods: Temporal properties of the photometric output were measured with an optical transient recorder. Luminances of the three color primaries and white for all 256 digital driving levels (DDLs) were measured with a spectroradiometer. Between the luminances of neighboring DDLs, just noticeable differences were calculated according to a perceptual model developed for medical displays. Luminances of full screen (FS) stimuli were compared to luminances of smaller stimuli with identical DDLs. Results: All measured luminance transition times were below 300 μs. Luminances were independent of the luminance in the preceding frame. However, for the single color primaries, up to 50.5% of the luminances of neighboring DDLs were not perceptually distinguishable. If two color primaries were active simultaneously, between 36.7% and 55.1% of neighboring luminances for increasing DDLs of the third primary were even decreasing. Moreover, luminance saturation effects were observed when too many pixels were active simultaneously. This effect was strongest for white; a small white patch was close to 400 cd/m2, but in FS the luminance of white saturated at 162 cd/m2. Due to different saturation levels, the luminance of FS green and FS yellow could exceed the luminance of FS white for identical DDLs. Conclusions: The OLED temporal characteristics are excellent and superior to those of LCDs. However, the OLEDs revealed severe perceptually relevant artifacts with implications for applicability to medical imaging. PMID:24007183

An evaluation of organic light emitting diode monitors for medical applications: great timing, but luminance artifacts.

PubMed

Elze, Tobias; Taylor, Christopher; Bex, Peter J

2013-09-01

In contrast to the dominant medical liquid crystal display (LCD) technology, organic light-emitting diode (OLED) monitors control the display luminance via separate light-emitting diodes for each pixel and are therefore supposed to overcome many previously documented temporal artifacts of medical LCDs. We assessed the temporal and luminance characteristics of the only currently available OLED monitor designed for use in the medical treatment field (SONY PVM2551MD) and checked the authors' main findings with another SONY OLED device (PVM2541). Temporal properties of the photometric output were measured with an optical transient recorder. Luminances of the three color primaries and white for all 256 digital driving levels (DDLs) were measured with a spectroradiometer. Between the luminances of neighboring DDLs, just noticeable differences were calculated according to a perceptual model developed for medical displays. Luminances of full screen (FS) stimuli were compared to luminances of smaller stimuli with identical DDLs. All measured luminance transition times were below 300 μs. Luminances were independent of the luminance in the preceding frame. However, for the single color primaries, up to 50.5% of the luminances of neighboring DDLs were not perceptually distinguishable. If two color primaries were active simultaneously, between 36.7% and 55.1% of neighboring luminances for increasing DDLs of the third primary were even decreasing. Moreover, luminance saturation effects were observed when too many pixels were active simultaneously. This effect was strongest for white; a small white patch was close to 400 cd/m(2), but in FS the luminance of white saturated at 162 cd/m(2). Due to different saturation levels, the luminance of FS green and FS yellow could exceed the luminance of FS white for identical DDLs. The OLED temporal characteristics are excellent and superior to those of LCDs. However, the OLEDs revealed severe perceptually relevant artifacts with implications for applicability to medical imaging.

Randomized clinical trial of two oral care regimens in reducing and controlling established dental plaque and gingivitis.

PubMed

Ayad, Farid; Mateo, Luis R; Dillon, Rensi; Miller, Jeffrey M; Pilch, Shira; Stewart, Bernal

2015-09-01

To evaluate the efficacy of a test regimen (TR) integrating the use of a commercially available triclosan, PVM/MA copolymer, and sodium fluoride containing toothpaste, an alcohol-free, fluoride-free cetylpyridinium chloride (CPC) mouthwash, and a manual toothbrush with cheek and tongue cleaner compared to a negative control regimen (NCR) integrating a commercially available 0.76% sodium monofluorophosphate toothpaste, a manual toothbrush and a fluoride-free and alcohol-free non-antibacterial mouthwash in the reduction and control of established plaque and gingivitis after 4 weeks of product use. A 4-week, two-cell, double-blind, parallel-group, randomized clinical study was conducted in Cedar Knolls, New Jersey, USA. Recruited subjects were randomly assigned to two regimens: (1) a commercially available toothpaste containing triclosan, PVM/MA copolymer, and 0.243% sodium fluoride, a manual toothbrush with cheek and tongue cleaner, and commercially available mouthwash containing 0.075% CPC in a fluoride-free and alcohol-free base (TR), or (2) a commercially available 0.76% sodium monofluorophosphate toothpaste, a manual toothbrush with rounded/polished bristles, and a fluoride-free and alcohol-free non-antibacterial mouthwash (NCR). Subjects were examined for dental plaque and gingivitis. Gingival, Gingival Severity, Gingival Interproximal, Plaque, Plaque Severity and Plaque Interproximal Index scores were calculated. For regimen comparison, independent t-test and ANCOVA analyses were performed. 130 subjects were screened; 120 enrolled; and 115 subjects completed the randomized clinical trial (RCT). After 4 weeks of product use, subjects using TR exhibited statistically significant (P < 0.001) reductions of 22.3%, 27.8% and 20.4% in mean Gingival, Gingival Severity and Gingival Interproximal Index scores, respectively, as compared to subjects using NCR. After 4 weeks of product use, subjects using TR exhibited statistically significant (P < 0.001) reductions of 28.2%, 60.7% and 27.6% in mean Plaque, Plaque Severity and Plaque Interproximal Index scores, respectively, as compared to subjects using NCR.

Vestibular Migraine in Children and Adolescents: Clinical Findings and Laboratory Tests

PubMed Central

Langhagen, Thyra; Lehrer, Nicole; Borggraefe, Ingo; Heinen, Florian; Jahn, Klaus

2015-01-01

Introduction: Vestibular migraine (VM) is the most common cause of episodic vertigo in children. We summarize the clinical findings and laboratory test results in a cohort of children and adolescents with VM. We discuss the limitations of current classification criteria for dizzy children. Methods: A retrospective chart analysis was performed on 118 children with migraine related vertigo at a tertiary care center. Patients were grouped in the following categories: (1) definite vestibular migraine (dVM); (2) probable vestibular migraine (pVM); (3) suspected vestibular migraine (sVM); (4) benign paroxysmal vertigo (BPV); and (5) migraine with/without aura (oM) plus vertigo/dizziness according to the International Classification of Headache Disorders, 3rd edition (beta version). Results: The mean age of all patients was 12 ± 3 years (range 3–18 years, 70 females). 36 patients (30%) fulfilled criteria for dVM, 33 (28%) for pVM, 34 (29%) for sVM, 7 (6%) for BPV, and 8 (7%) for oM. Somatoform vertigo (SV) co-occurred in 27% of patients. Episodic syndromes were reported in 8%; the family history of migraine was positive in 65%. Mild central ocular motor signs were found in 24% (most frequently horizontal saccadic pursuit). Laboratory tests showed that about 20% had pathological function of the horizontal vestibulo-ocular reflex, and almost 50% had abnormal postural sway patterns. Conclusion: Patients with definite, probable, and suspected VM do not differ in the frequency of ocular motor, vestibular, or postural abnormalities. VM is the best explanation for their symptoms. It is essential to establish diagnostic criteria in clinical studies. In clinical practice, however, the most reasonable diagnosis should be made in order to begin treatment. Such a procedure also minimizes the fear of the parents and children, reduces the need to interrupt leisure time and school activities, and prevents the development of SV. PMID:25674076

Automatic programming for critical applications

NASA Technical Reports Server (NTRS)

Loganantharaj, Raj L.

1988-01-01

The important phases of a software life cycle include verification and maintenance. Usually, the execution performance is an expected requirement in a software development process. Unfortunately, the verification and the maintenance of programs are the time consuming and the frustrating aspects of software engineering. The verification cannot be waived for the programs used for critical applications such as, military, space, and nuclear plants. As a consequence, synthesis of programs from specifications, an alternative way of developing correct programs, is becoming popular. The definition, or what is understood by automatic programming, has been changed with our expectations. At present, the goal of automatic programming is the automation of programming process. Specifically, it means the application of artificial intelligence to software engineering in order to define techniques and create environments that help in the creation of high level programs. The automatic programming process may be divided into two phases: the problem acquisition phase and the program synthesis phase. In the problem acquisition phase, an informal specification of the problem is transformed into an unambiguous specification while in the program synthesis phase such a specification is further transformed into a concrete, executable program.

Yoga therapy for developing emotional intelligence in mid-life managers.

PubMed

Ganpat, Tikhe Sham; Nagendra, H R

2011-01-01

Business executives' lives have become a never-ending race against time, technology, and targets. This race creates tension, which leads to dissatisfaction and frustration and eventually manifests itself as psychological and physiological stress with mental and emotional drain. This modern lifestyle intensifies the stress leading to "excessive tension" and consequent deterioration in "executive efficiency". To assess emotional intelligent quotient (EQ) in managers undergoing yoga-based Self Management of Excessive Tension (SMET) program. 72 managers participated in this study which is of "single group pre-post design." The EQ test developed by Prof N. K. Chadha from University of Delhi was administered as pre and post the 5 days of SMET program. Means, standard deviations, Kolmogorov-Smirnov test, and Wilcoxon signed rank test were used to analyze the data. The data analysis showed 72.02% significant increase (P<0.001) in EQ. The results suggest that participation in a SMET program was associated with improvement in EQ and may have implications for "executive efficiency."

78 FR 26485 - Community Programs Guaranteed Loans

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-07

... community facility such as childcare, educational, or health care facilities; and amending Sec. 3575.25... manner delineated in 7 CFR part 3015, subpart V. Executive Order 12988, Civil Justice Reform This rule has been reviewed under Executive Order 12988, Civil Justice Reform. In accordance with this rule: (1...

High-Impact Succession Management. Executive Summary

ERIC Educational Resources Information Center

Lamoureux, Kim; Campbell, Michael; Smith, Roland

2009-01-01

Most companies have an opportunity to improve their succession management programs. The number one challenge for succession management (as identified by both HR leaders and executives) is developing a succession planning strategy. This comprehensive industry study sets out to determine how succession management (when done well) helps improve…

5 CFR 2638.703 - Initial agency ethics orientation for all employees.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 3 2011-01-01 2011-01-01 false Initial agency ethics orientation for all employees. 2638.703 Section 2638.703 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Executive Agency Ethics...