Sample records for q-space mri presidential

  1. Joint 6D k-q Space Compressed Sensing for Accelerated High Angular Resolution Diffusion MRI.

    PubMed

    Cheng, Jian; Shen, Dinggang; Basser, Peter J; Yap, Pew-Thian

    2015-01-01

    High Angular Resolution Diffusion Imaging (HARDI) avoids the Gaussian. diffusion assumption that is inherent in Diffusion Tensor Imaging (DTI), and is capable of characterizing complex white matter micro-structure with greater precision. However, HARDI methods such as Diffusion Spectrum Imaging (DSI) typically require significantly more signal measurements than DTI, resulting in prohibitively long scanning times. One of the goals in HARDI research is therefore to improve estimation of quantities such as the Ensemble Average Propagator (EAP) and the Orientation Distribution Function (ODF) with a limited number of diffusion-weighted measurements. A popular approach to this problem, Compressed Sensing (CS), affords highly accurate signal reconstruction using significantly fewer (sub-Nyquist) data points than required traditionally. Existing approaches to CS diffusion MRI (CS-dMRI) mainly focus on applying CS in the q-space of diffusion signal measurements and fail to take into consideration information redundancy in the k-space. In this paper, we propose a framework, called 6-Dimensional Compressed Sensing diffusion MRI (6D-CS-dMRI), for reconstruction of the diffusion signal and the EAP from data sub-sampled in both 3D k-space and 3D q-space. To our knowledge, 6D-CS-dMRI is the first work that applies compressed sensing in the full 6D k-q space and reconstructs the diffusion signal in the full continuous q-space and the EAP in continuous displacement space. Experimental results on synthetic and real data demonstrate that, compared with full DSI sampling in k-q space, 6D-CS-dMRI yields excellent diffusion signal and EAP reconstruction with low root-mean-square error (RMSE) using 11 times less samples (3-fold reduction in k-space and 3.7-fold reduction in q-space).

  2. q-Space Upsampling Using x-q Space Regularization.

    PubMed

    Chen, Geng; Dong, Bin; Zhang, Yong; Shen, Dinggang; Yap, Pew-Thian

    2017-09-01

    Acquisition time in diffusion MRI increases with the number of diffusion-weighted images that need to be acquired. Particularly in clinical settings, scan time is limited and only a sparse coverage of the vast q -space is possible. In this paper, we show how non-local self-similar information in the x - q space of diffusion MRI data can be harnessed for q -space upsampling. More specifically, we establish the relationships between signal measurements in x - q space using a patch matching mechanism that caters to unstructured data. We then encode these relationships in a graph and use it to regularize an inverse problem associated with recovering a high q -space resolution dataset from its low-resolution counterpart. Experimental results indicate that the high-resolution datasets reconstructed using the proposed method exhibit greater quality, both quantitatively and qualitatively, than those obtained using conventional methods, such as interpolation using spherical radial basis functions (SRBFs).

  3. XQ-NLM: Denoising Diffusion MRI Data via x-q Space Non-Local Patch Matching.

    PubMed

    Chen, Geng; Wu, Yafeng; Shen, Dinggang; Yap, Pew-Thian

    2016-10-01

    Noise is a major issue influencing quantitative analysis in diffusion MRI. The effects of noise can be reduced by repeated acquisitions, but this leads to long acquisition times that can be unrealistic in clinical settings. For this reason, post-acquisition denoising methods have been widely used to improve SNR. Among existing methods, non-local means (NLM) has been shown to produce good image quality with edge preservation. However, currently the application of NLM to diffusion MRI has been mostly focused on the spatial space (i.e., the x -space), despite the fact that diffusion data live in a combined space consisting of the x -space and the q -space (i.e., the space of wavevectors). In this paper, we propose to extend NLM to both x -space and q -space. We show how patch-matching, as required in NLM, can be performed concurrently in x-q space with the help of azimuthal equidistant projection and rotation invariant features. Extensive experiments on both synthetic and real data confirm that the proposed x-q space NLM (XQ-NLM) outperforms the classic NLM.

  4. Presidential Leadership in the Development of the U.S. Space Program

    NASA Technical Reports Server (NTRS)

    Launius, Roger D. (Editor); Mccurdy, Howard E. (Editor)

    1994-01-01

    Papers presented at a historical symposium on Presidential leadership in the space program include the following: 'The Imperial Presidency in the History of Space Exploration'; 'The Reluctant Racer: Dwight D. Eisenhower and United States Space Policy'; 'Kennedy and the Decision to Go to the Moon'; 'Johnson, Project Apollo, and the Politics of Space Program Planning'; 'The Presidency, Congress, and the Deceleration of the U.S. Space Program in the 1970s'; 'Politics not Science: The U.S. Space Program in the Reagan and Bush Years'; 'Presidential Leadership and International Aspects of the Space Program'; 'National Leadership and Presidential Power'; and 'Epilogue: Beyond NASA Exceptionalism'.

  5. Prospective estimation of mean axon diameter and extra-axonal space of the posterior limb of the internal capsule in patients with idiopathic normal pressure hydrocephalus before and after a lumboperitoneal shunt by using q-space diffusion MRI.

    PubMed

    Hori, Masaaki; Kamiya, Kouhei; Nakanishi, Atsushi; Fukunaga, Issei; Miyajima, Masakazu; Nakajima, Madoka; Suzuki, Michimasa; Suzuki, Yuriko; Irie, Ryusuke; Kamagata, Koji; Arai, Hajime; Aoki, Shigeki

    2016-09-01

    To prospectively estimate the mean axon diameter (MAD) and extracellular space of the posterior limb of the internal capsule (PLIC) in patients with idiopathic normal pressure hydrocephalus (iNPH) before and after a lumboperitoneal (LP) shunting operation using q-space diffusion MRI analysis. We studied 12 consecutive patients with iNPH and 12 controls at our institution. After conventional magnetic resonance imaging (MRI), q-space image (QSI) data were acquired with a 3-T MRI scanner. The MAD and extra-axonal space of the PLIC before and after LP shunting were calculated using two-component q-space imaging analyses; the before and after values were compared. After LP shunt surgery, the extracellular space of the PLIC was significantly higher than that of the same patients before the operation (one-way analysis of variance (ANOVA) with Scheffé's post-hoc test, P = 0.024). No significant differences were observed in the PLIC axon diameters among normal controls or in patients before and after surgery. Increases in the root mean square displacement in the extra-axonal space of the PLIC in patients with iNPH after an LP shunt procedure are associated with the microstructural changes of white matter and subsequent abatement of patient symptoms. • Q-space diffusion MRI provides information on microstructural changes in the corticospinal tract • Lumboperitoneal (LP) shunting operation is useful for idiopathic normal pressure hydrocephalus • Q-space measurement may be a biomarker for the effect of the LP shunt procedure.

  6. Assessing the multiscale architecture of muscular tissue with Q-space magnetic resonance imaging: Review.

    PubMed

    Hoffman, Matthew P; Taylor, Erik N; Aninwene, George E; Sadayappan, Sakthivel; Gilbert, Richard J

    2018-02-01

    Contraction of muscular tissue requires the synchronized shortening of myofibers arrayed in complex geometrical patterns. Imaging such myofiber patterns with diffusion-weighted MRI reveals architectural ensembles that underlie force generation at the organ scale. Restricted proton diffusion is a stochastic process resulting from random translational motion that may be used to probe the directionality of myofibers in whole tissue. During diffusion-weighted MRI, magnetic field gradients are applied to determine the directional dependence of proton diffusion through the analysis of a diffusional probability distribution function (PDF). The directions of principal (maximal) diffusion within the PDF are associated with similarly aligned diffusion maxima in adjacent voxels to derive multivoxel tracts. Diffusion-weighted MRI with tractography thus constitutes a multiscale method for depicting patterns of cellular organization within biological tissues. We provide in this review, details of the method by which generalized Q-space imaging is used to interrogate multidimensional diffusion space, and thereby to infer the organization of muscular tissue. Q-space imaging derives the lowest possible angular separation of diffusion maxima by optimizing the conditions by which magnetic field gradients are applied to a given tissue. To illustrate, we present the methods and applications associated with Q-space imaging of the multiscale myoarchitecture associated with the human and rodent tongues. These representations emphasize the intricate and continuous nature of muscle fiber organization and suggest a method to depict structural "blueprints" for skeletal and cardiac muscle tissue. © 2016 Wiley Periodicals, Inc.

  7. Report of the Presidential Commission on the Space Shuttle Challenger Accident, Volume 5

    NASA Technical Reports Server (NTRS)

    1986-01-01

    This volume contains all the hearings of the Presidential Commission on the Space Shuttle Challenger accident from 26 February to 2 May 1986. Among others is the testimony of L. Mulloy, Manager, Space Shuttle Solid Rocket Booster Program, Marshall Space Flight Center and G. Hardy, Deputy Director, Science and Engineering, Marshall Space Flight Center.

  8. Q-space trajectory imaging for multidimensional diffusion MRI of the human brain

    PubMed Central

    Westin, Carl-Fredrik; Knutsson, Hans; Pasternak, Ofer; Szczepankiewicz, Filip; Özarslan, Evren; van Westen, Danielle; Mattisson, Cecilia; Bogren, Mats; O’Donnell, Lauren; Kubicki, Marek; Topgaard, Daniel; Nilsson, Markus

    2016-01-01

    This work describes a new diffusion MR framework for imaging and modeling of microstructure that we call q-space trajectory imaging (QTI). The QTI framework consists of two parts: encoding and modeling. First we propose q-space trajectory encoding, which uses time-varying gradients to probe a trajectory in q-space, in contrast to traditional pulsed field gradient sequences that attempt to probe a point in q-space. Then we propose a microstructure model, the diffusion tensor distribution (DTD) model, which takes advantage of additional information provided by QTI to estimate a distributional model over diffusion tensors. We show that the QTI framework enables microstructure modeling that is not possible with the traditional pulsed gradient encoding as introduced by Stejskal and Tanner. In our analysis of QTI, we find that the well-known scalar b-value naturally extends to a tensor-valued entity, i.e., a diffusion measurement tensor, which we call the b-tensor. We show that b-tensors of rank 2 or 3 enable estimation of the mean and covariance of the DTD model in terms of a second order tensor (the diffusion tensor) and a fourth order tensor. The QTI framework has been designed to improve discrimination of the sizes, shapes, and orientations of diffusion microenvironments within tissue. We derive rotationally invariant scalar quantities describing intuitive microstructural features including size, shape, and orientation coherence measures. To demonstrate the feasibility of QTI on a clinical scanner, we performed a small pilot study comparing a group of five healthy controls with five patients with schizophrenia. The parameter maps derived from QTI were compared between the groups, and 9 out of the 14 parameters investigated showed differences between groups. The ability to measure and model the distribution of diffusion tensors, rather than a quantity that has already been averaged within a voxel, has the potential to provide a powerful paradigm for the study of

  9. Earth and space science community responds to U.S. presidential election

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2012-11-01

    Following the 6 November reelection of U.S. president Barack Obama, Eos contacted a number of scientists and analysts involved with the Earth and space sciences. Each was asked (1) for their thoughts about what impact the presidential election will have on the Earth and space sciences and (2) what they see as the key challenges and what the Obama administration should have at the top of its agenda related to the geosciences. Here are 13 responses.

  10. 14 CFR 294.51 - Presidential review.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Presidential review. 294.51 Section 294.51 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS CANADIAN CHARTER AIR TAXI OPERATORS Cancellation of Registration and Presidential Review § 294.51...

  11. Report of the Presidential Commission on the Space Shuttle Challenger Accident, Volume 4

    NASA Technical Reports Server (NTRS)

    1986-01-01

    This volume contains all the hearings of the Presidential Commission on the Space Shuttle Challenger accident from 6 February to 25 February 1986. Among others, the testimony of NASA's acting administrator William R. Graham is included.

  12. Depletion-Mode GaN HEMT Q-Spoil Switches for MRI Coils

    PubMed Central

    Lu, Jonathan Y.; Grafendorfer, Thomas; Zhang, Tao; Vasanawala, Shreyas; Robb, Fraser; Pauly, John M.; Scott, Greig C.

    2017-01-01

    Q-spoiling is the process of decoupling an MRI receive coil to protect the equipment and patient. Conventionally, Q-spoiling is performed using a PIN diode switch that draws significant current. In this work, a Q-spoiling technique using a depletion-mode Gallium Nitride HEMT device was developed for coil detuning at both 1.5 T and 3 T MRI. The circuits with conventional PIN diode Q-spoiling and the GaN HEMT device were implemented on surface coils. SNR was measured and compared for all surfaces coils. At both 1.5 T and 3 T, comparable SNR was achieved for all coils with the proposed technique and conventional Q-spoiling. The GaN HEMT device has significantly reduced the required power for Q-spoiling. The GaN HEMT device also provides useful safety features by detuning the coil when unpowered. PMID:27362895

  13. 14 CFR 294.51 - Presidential review.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Presidential review. 294.51 Section 294.51... REGULATIONS CANADIAN CHARTER AIR TAXI OPERATORS Cancellation of Registration and Presidential Review § 294.51 Presidential review. A Department order under § 294.50 (e), (g) or (i) shall be subject to stay or disapproval...

  14. Radial q-space sampling for DSI

    PubMed Central

    Baete, Steven H.; Yutzy, Stephen; Boada, Fernando, E.

    2015-01-01

    Purpose Diffusion Spectrum Imaging (DSI) has been shown to be an effective tool for non-invasively depicting the anatomical details of brain microstructure. Existing implementations of DSI sample the diffusion encoding space using a rectangular grid. Here we present a different implementation of DSI whereby a radially symmetric q-space sampling scheme for DSI (RDSI) is used to improve the angular resolution and accuracy of the reconstructed Orientation Distribution Functions (ODF). Methods Q-space is sampled by acquiring several q-space samples along a number of radial lines. Each of these radial lines in q-space is analytically connected to a value of the ODF at the same angular location by the Fourier slice theorem. Results Computer simulations and in vivo brain results demonstrate that RDSI correctly estimates the ODF when moderately high b-values (4000 s/mm2) and number of q-space samples (236) are used. Conclusion The nominal angular resolution of RDSI depends on the number of radial lines used in the sampling scheme, and only weakly on the maximum b-value. In addition, the radial analytical reconstruction reduces truncation artifacts which affect Cartesian reconstructions. Hence, a radial acquisition of q-space can be favorable for DSI. PMID:26363002

  15. Radial q-space sampling for DSI.

    PubMed

    Baete, Steven H; Yutzy, Stephen; Boada, Fernando E

    2016-09-01

    Diffusion spectrum imaging (DSI) has been shown to be an effective tool for noninvasively depicting the anatomical details of brain microstructure. Existing implementations of DSI sample the diffusion encoding space using a rectangular grid. Here we present a different implementation of DSI whereby a radially symmetric q-space sampling scheme for DSI is used to improve the angular resolution and accuracy of the reconstructed orientation distribution functions. Q-space is sampled by acquiring several q-space samples along a number of radial lines. Each of these radial lines in q-space is analytically connected to a value of the orientation distribution functions at the same angular location by the Fourier slice theorem. Computer simulations and in vivo brain results demonstrate that radial diffusion spectrum imaging correctly estimates the orientation distribution functions when moderately high b-values (4000 s/mm2) and number of q-space samples (236) are used. The nominal angular resolution of radial diffusion spectrum imaging depends on the number of radial lines used in the sampling scheme, and only weakly on the maximum b-value. In addition, the radial analytical reconstruction reduces truncation artifacts which affect Cartesian reconstructions. Hence, a radial acquisition of q-space can be favorable for DSI. Magn Reson Med 76:769-780, 2016. © 2015 Wiley Periodicals, Inc. © 2015 Wiley Periodicals, Inc.

  16. Report of the Presidential Commission on the Space Shuttle Challenger Accident. Volume 1

    DTIC Science & Technology

    1986-06-06

    of February 3 , 1986, the undersigned present the report of the Presidential Commission on the Space Shuttle Challenger Accident. Chairman, Maryland...spacecraft had flown twice. Failure of a fuel cell shortened the flight by about three days. ■ STS- 3 , March 22-30, 1982, Orbiter Colum- bia, was the...Flight 10 (41-B), February 3 -11, 1984, Or- biter Challenger, was highlighted by the in- troduction of the Manned Maneuvering Unit, a backpack

  17. A 4D Hyperspherical Interpretation of q-Space

    PubMed Central

    Hosseinbor, A. Pasha; Chung, Moo K.; Wu, Yu-Chien; Bendlin, Barbara B.; Alexander, Andrew L.

    2015-01-01

    3D q-space can be viewed as the surface of a 4D hypersphere. In this paper, we seek to develop a 4D hyperspherical interpretation of q-space by projecting it onto a hypersphere and subsequently modeling the q-space signal via 4D hyperspherical harmonics (HSH). Using this orthonormal basis, we derive several well-established q-space indices and numerically estimate the diffusion orientation distribution function (dODF). We also derive the integral transform describing the relationship between the diffusion signal and propagator on a hypersphere. Most importantly, we will demonstrate that for hybrid diffusion imaging (HYDI) acquisitions low order linear expansion of the HSH basis is sufficient to characterize diffusion in neural tissue. In fact, the HSH basis achieves comparable signal and better dODF reconstructions than other well-established methods, such as Bessel Fourier orientation reconstruction (BFOR), using fewer fitting parameters. All in all, this work provides a new way of looking at q-space. PMID:25624043

  18. A 4D hyperspherical interpretation of q-space.

    PubMed

    Pasha Hosseinbor, A; Chung, Moo K; Wu, Yu-Chien; Bendlin, Barbara B; Alexander, Andrew L

    2015-04-01

    3D q-space can be viewed as the surface of a 4D hypersphere. In this paper, we seek to develop a 4D hyperspherical interpretation of q-space by projecting it onto a hypersphere and subsequently modeling the q-space signal via 4D hyperspherical harmonics (HSH). Using this orthonormal basis, we derive several well-established q-space indices and numerically estimate the diffusion orientation distribution function (dODF). We also derive the integral transform describing the relationship between the diffusion signal and propagator on a hypersphere. Most importantly, we will demonstrate that for hybrid diffusion imaging (HYDI) acquisitions low order linear expansion of the HSH basis is sufficient to characterize diffusion in neural tissue. In fact, the HSH basis achieves comparable signal and better dODF reconstructions than other well-established methods, such as Bessel Fourier orientation reconstruction (BFOR), using fewer fitting parameters. All in all, this work provides a new way of looking at q-space. Copyright © 2014 Elsevier B.V. All rights reserved.

  19. k-space and q-space: combining ultra-high spatial and angular resolution in diffusion imaging using ZOOPPA at 7 T.

    PubMed

    Heidemann, Robin M; Anwander, Alfred; Feiweier, Thorsten; Knösche, Thomas R; Turner, Robert

    2012-04-02

    There is ongoing debate whether using a higher spatial resolution (sampling k-space) or a higher angular resolution (sampling q-space angles) is the better way to improve diffusion MRI (dMRI) based tractography results in living humans. In both cases, the limiting factor is the signal-to-noise ratio (SNR), due to the restricted acquisition time. One possible way to increase the spatial resolution without sacrificing either SNR or angular resolution is to move to a higher magnetic field strength. Nevertheless, dMRI has not been the preferred application for ultra-high field strength (7 T). This is because single-shot echo-planar imaging (EPI) has been the method of choice for human in vivo dMRI. EPI faces several challenges related to the use of a high resolution at high field strength, for example, distortions and image blurring. These problems can easily compromise the expected SNR gain with field strength. In the current study, we introduce an adapted EPI sequence in conjunction with a combination of ZOOmed imaging and Partially Parallel Acquisition (ZOOPPA). We demonstrate that the method can produce high quality diffusion-weighted images with high spatial and angular resolution at 7 T. We provide examples of in vivo human dMRI with isotropic resolutions of 1 mm and 800 μm. These data sets are particularly suitable for resolving complex and subtle fiber architectures, including fiber crossings in the white matter, anisotropy in the cortex and fibers entering the cortex. Copyright © 2011 Elsevier Inc. All rights reserved.

  20. Presidential leadership.

    PubMed

    Goethals, George R

    2005-01-01

    This chapter reviews psychological theories of leadership and selected literature on the American presidency to highlight key psychological principles of presidential leadership. Psychological theories, framed by the principles of leadership outlined by Freud (1921), include those of Burns (1978, 2003) on transformational leadership, Bass (1997) and House & Shamir (1993) on charismatic and transformational leadership, Gardner (1995) on stories of identity, Hogg (2001, 2003) on social identity, and Tyler & Lind (1992) on procedural justice. The discussion of presidential scholarship considers work by Barber (1992) on presidential character, Simonton (1986, 1987) on presidential personality and success, Skowronek (1997) on reconstructive politics, and Winter (1987) on presidential motive profiles. These studies suggest that followers have high expectations for presidents and that successful presidential leadership depends on opportunity, high levels of activity, intelligence, optimistic resilience, and flexibility.

  1. Presidential Storytelling as Argument: The Functions and Characteristics of Presidential Stories.

    ERIC Educational Resources Information Center

    Holloway, Rachel L.

    Noting the persistence of presidential "story" despite its critics, this paper maintains that presidential storytelling involves rhetorical skill and yields rhetorical benefits, and thus qualifies as strategic discourse. Initially examining presidential stories disguised as reports, termed "presidential episodes," the paper…

  2. Speaking two "Languages" in America: A semantic space analysis of how presidential candidates and their supporters represent abstract political concepts differently.

    PubMed

    Li, Ping; Schloss, Benjamin; Follmer, D Jake

    2017-10-01

    In this article we report a computational semantic analysis of the presidential candidates' speeches in the two major political parties in the USA. In Study One, we modeled the political semantic spaces as a function of party, candidate, and time of election, and findings revealed patterns of differences in the semantic representation of key political concepts and the changing landscapes in which the presidential candidates align or misalign with their parties in terms of the representation and organization of politically central concepts. Our models further showed that the 2016 US presidential nominees had distinct conceptual representations from those of previous election years, and these patterns did not necessarily align with their respective political parties' average representation of the key political concepts. In Study Two, structural equation modeling demonstrated that reported political engagement among voters differentially predicted reported likelihoods of voting for Clinton versus Trump in the 2016 presidential election. Study Three indicated that Republicans and Democrats showed distinct, systematic word association patterns for the same concepts/terms, which could be reliably distinguished using machine learning methods. These studies suggest that given an individual's political beliefs, we can make reliable predictions about how they understand words, and given how an individual understands those same words, we can also predict an individual's political beliefs. Our study provides a bridge between semantic space models and abstract representations of political concepts on the one hand, and the representations of political concepts and citizens' voting behavior on the other.

  3. Introduction. Presidential disability and presidential succession.

    PubMed

    Gilbert, Robert E; Bucy, Erik P

    2014-01-01

    This introduction to the special issue on presidential disability and succession focuses on the distinctly positive contributions that invocations of the Twenty-Fifth Amendment have made to American political life since the Amendment's ratification in 1967. It also underlines the importance for Presidents, their family members and aides to understand the necessity for putting the welfare of the country first, above all else-even at times above the wishes of a disabled Chief Executive. As the articles in this special issue make clear, the Twenty-Fifth Amendment provides an effective constitutional mechanism by which the country's well-being can be maintained while simultaneously showing compassion and respect for a disabled leader. The idea for this issue emerged from a conference organized by Professor Robert E. Gilbert focusing on presidential disability and succession held on the campus of Northeastern University in April 2014. Papers from the conference assembled here clarify and add to the historical record about presidential inability while illuminating the many political, legal, and constitutional contingencies that future presidential administrators may face. Contributors to this issue have varied disciplinary and professional backgrounds, including expertise in American politics, constitutional law, the presidency and vice presidency, presidential impairment, and, of course, the Twenty-Fifth Amendment to the Constitution.

  4. TH-EF-BRA-06: A Novel Retrospective 3D K-Space Sorting 4D-MRI Technique Using a Radial K-Space Acquisition MRI Sequence

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Liu, Y; Subashi, E; Yin, F

    Purpose: Current retrospective 4D-MRI provides superior tumor-to-tissue contrast and accurate respiratory motion information for radiotherapy motion management. The developed 4D-MRI techniques based on 2D-MRI image sorting require a high frame-rate of the MR sequences. However, several MRI sequences provide excellent image quality but have low frame-rate. This study aims at developing a novel retrospective 3D k-space sorting 4D-MRI technique using radial k-space acquisition MRI sequences to improve 4D-MRI image quality and temporal-resolution for imaging irregular organ/tumor respiratory motion. Methods: The method is based on a RF-spoiled, steady-state, gradient-recalled sequence with minimal echo time. A 3D radial k-space data acquisition trajectorymore » was used for sampling the datasets. Each radial spoke readout data line starts from the 3D center of Field-of-View. Respiratory signal can be extracted from the k-space center data point of each spoke. The spoke data was sorted based on its self-synchronized respiratory signal using phase sorting. Subsequently, 3D reconstruction was conducted to generate the time-resolved 4D-MRI images. As a feasibility study, this technique was implemented on a digital human phantom XCAT. The respiratory motion was controlled by an irregular motion profile. To validate using k-space center data as a respiratory surrogate, we compared it with the XCAT input controlling breathing profile. Tumor motion trajectories measured on reconstructed 4D-MRI were compared to the average input trajectory. The mean absolute amplitude difference (D) was calculated. Results: The signal extracted from k-space center data matches well with the input controlling respiratory profile of XCAT. The relative amplitude error was 8.6% and the relative phase error was 3.5%. XCAT 4D-MRI demonstrated a clear motion pattern with little serrated artifacts. D of tumor trajectories was 0.21mm, 0.23mm and 0.23mm in SI, AP and ML directions, respectively

  5. A thermodynamic-like characterization of Colombia’s presidential elections in 2010, and a comparison with other Latin American countries

    NASA Astrophysics Data System (ADS)

    Campos, Diógenes

    2011-05-01

    A thermodynamic-like characterization of Colombia’s presidential election is presented. We assume that the electoral system consists of citizens embedded in a political environment, and that this environment can be considered as an information bath characterized by the entropic parameter q ( q∈[0,∞]). First, for q=1, the electoral outcomes of 2010 are translated into a set of probabilities (relative frequencies of the events) P={P1,P2,…,PN}, with N possible independent results. Then, for 0≤q<∞, the electoral system is characterized by using the thermodynamic-like method for probabilistic systems proposed in a previous article. Some general considerations of the macro-description of a probabilistic system and a comparison of presidential elections in five countries are also included.

  6. Technology Assessment in Support of the Presidential Vision for Space Exploration

    NASA Technical Reports Server (NTRS)

    Weisbin, Charles R.; Lincoln, William; Mrozinski, Joe; Hua, Hook; Merida, Sofia; Shelton, Kacie; Adumitroaie, Virgil; Derleth, Jason; Silberg, Robert

    2006-01-01

    This paper discusses the process and results of technology assessment in support of the United States Vision for Space Exploration of the Moon, Mars and Beyond. The paper begins by reviewing the Presidential Vision: a major endeavor in building systems of systems. It discusses why we wish to return to the Moon, and the exploration architecture for getting there safely, sustaining a presence, and safely returning. Next, a methodology for optimal technology investment is proposed with discussion of inputs including a capability hierarchy, mission importance weightings, available resource profiles as a function of time, likelihoods of development success, and an objective function. A temporal optimization formulation is offered, and the investment recommendations presented along with sensitivity analyses. Key questions addressed are sensitivity of budget allocations to cost uncertainties, reduction in available budget levels, and shifting funding within constraints imposed by mission timeline.

  7. Long-Duration Space Flight Provokes Pathologic Q-Tc Interval Prolongation

    NASA Technical Reports Server (NTRS)

    D'Aunno, DOminick S.; Dougherty, Anne H.; DeBlock, Heidi F.; Meck, Janice V.

    2002-01-01

    Space flight has a profound influence on the cardiovascular and autonomic nervous systems. Alterations in baroreflex function, plasma catecholamine concentrations, and arterial pressure regulation have been observed. Changes in autonomic regulation of cardiac function may lead to serious rhythm disturbances. In fact, ventricular tachycardia has been reported during long-duration space flight. The study aim was to determine the effects of space flight on cardiac conduction. Methods and Results: Electrocardiograms (ECGs) and serum electrolytes were obtained before and after short-duration (SD) (4-16 days) and long-duration (LD) (4-6 months) missions. Holter recordings were obtained from 3 different subjects before, during and after a 4-month mission. P-R, R-R, and Q-T intervals were measured manually in a random, blinded fashion and Bazzet's formula used to correct the Q-T interval (Q-Tc). Space flight had no clinically significant effect on electrolyte concentrations. P-R and RR intervals were decreased after SD flight (p<0.05) and recovered 3 days after landing. In the same subjects, P-R and Q-Tc intervals were prolonged after LD flight (p<0.01). Clinically significant Q-Tc prolongation (>0.44 sec) occurred during the first month of flight and persisted until 3 days after landing (p<0.01). Conclusions - Space flight alters cardiac conduction with more ominous changes seen with LD missions. Alterations in autonomic tone may explain ECG changes associated with space flight. Primary cardiac changes may also contribute to the conduction changes with LD flight. Q-Tc prolongation may predispose astronauts to ventricular arrhythmias during and after long-duration space flight.

  8. Modeling Hubble Space Telescope flight data by Q-Markov cover identification

    NASA Technical Reports Server (NTRS)

    Liu, K.; Skelton, R. E.; Sharkey, J. P.

    1992-01-01

    A state space model for the Hubble Space Telescope under the influence of unknown disturbances in orbit is presented. This model was obtained from flight data by applying the Q-Markov covariance equivalent realization identification algorithm. This state space model guarantees the match of the first Q-Markov parameters and covariance parameters of the Hubble system. The flight data were partitioned into high- and low-frequency components for more efficient Q-Markov cover modeling, to reduce some computational difficulties of the Q-Markov cover algorithm. This identification revealed more than 20 lightly damped modes within the bandwidth of the attitude control system. Comparisons with the analytical (TREETOPS) model are also included.

  9. Implementation of the Recommendations of the Presidential Commission on the Space Shuttle Challenger Accident

    NASA Technical Reports Server (NTRS)

    1987-01-01

    This final status report describes the actions taken by NASA in response to the recommendations of the Presidential Commission on the Space Shuttle Challenger Accident (Mission 51-L). The Commission recommendations and NASA's responses to them are summarized in the Executive Summary, which is accompanied by a schedule showing significant program milestones. A detailed discussion of the activities undertaken by NASA to implement each of the nine Commission recommendations is included and other related NASA actions required for safe return to flight are discussed. A copy of the interim plan submitted to the President one year ago and other significant reference documents are included as appendixes.

  10. 3 CFR - Presidential Signing Statements

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 3 The President 1 2010-01-01 2010-01-01 false Presidential Signing Statements Presidential Documents Other Presidential Documents Memorandum of March 9, 2009 Presidential Signing Statements Memorandum for the Heads of Executive Departments and Agencies For nearly two centuries, Presidents have issued statements addressing constitutional or other...

  11. PRESIDENTIAL COMMISSION - STS-33/51L - KSC

    NASA Image and Video Library

    1986-03-07

    S86-28889 (14 Feb. 1986) --- Kennedy Space Center Director Richard Smith points out a portion of a solid rocket booster segment to astronaut Sally Ride and to the chairman of the Presidential Commission on the Space Shuttle Challenger Accident, William P. Rogers. The commission was taken to various booster storage and handling facilities at KSC on Feb. 14, 1986 as part of the failure investigation. Photo credit: NASA

  12. Light scattering Q-space analysis of irregularly shaped particles

    NASA Astrophysics Data System (ADS)

    Heinson, Yuli W.; Maughan, Justin B.; Heinson, William R.; Chakrabarti, Amitabha; Sorensen, Christopher M.

    2016-01-01

    We report Q-space analysis of light scattering phase function data for irregularly shaped dust particles and of theoretical model output to describe them. This analysis involves plotting the scattered intensity versus the magnitude of the scattering wave vector q = (4π/λ)sin(θ/2), where λ is the optical wavelength and θ is the scattering angle, on a double-logarithmic plot. In q-space all the particle shapes studied display a scattering pattern which includes a q-independent forward scattering regime; a crossover, Guinier regime when q is near the inverse size; a power law regime; and an enhanced backscattering regime. Power law exponents show a quasi-universal functionality with the internal coupling parameter ρ'. The absolute value of the exponents start from 4 when ρ' < 1, the diffraction limit, and decreases as ρ' increases until a constant 1.75 ± 0.25 when ρ' ≳ 10. The diffraction limit exponent implies that despite their irregular structures, all the particles studied have mass and surface scaling dimensions of Dm = 3 and Ds = 2, respectively. This is different from fractal aggregates that have a power law equal to the fractal dimension Df because Df = Dm = Ds < 3. Spheres have Dm = 3 and Ds = 2 but do not show a single power law nor the same functionality with ρ'. The results presented here imply that Q-space analysis can differentiate between spheres and these two types of irregularly shaped particles. Furthermore, they are applicable to analysis of the contribution of aerosol radiative forcing to climate change and of aerosol remote sensing data.

  13. Actions to Implement the Recommendations of the Presidential Commission on the Space Shuttle Challenger Accident: Executive Summary

    NASA Technical Reports Server (NTRS)

    1986-01-01

    The status of the implementation of the recommendations of the Presidential Commission on the Space Shuttle Challenger Accident is reported. The implementation of recommendations in the following areas is detailed: (1) solid rocket motor design; (2) shuttle management structure, including the shuttle safety panel and astronauts in management; (3) critical item review and hazard analysis; (4) safety organization; (5) improved communication; (6) landing safety; (7) launch abort and crew escape; (8) flight rate; and (9) maintenance safeguards. Supporting memoranda and communications from NASA are appended.

  14. Presidential commission investigating Challenger accident at JSC

    NASA Image and Video Library

    1986-03-05

    S86-28751 (5 March 1986) --- Two NASA officials talk with members of the Presidential Commission on the Space Shuttle Challenger Accident in the Executive Conference Room of JSC’s Project Management Building. Left to right are JSC Deputy Director Robert C. Goetz; Richard H. Kohrs, Deputy Manager, National Space Transportation Systems Office; and commission members Dr. Arthur B.C. Walker Jr., Robert W. Rummel and Joseph F. Sutter. Photo credit: NASA

  15. Presidential commission investigating Challenger accident at JSC

    NASA Image and Video Library

    1986-03-05

    S86-28750 (5 March 1986) --- Two JSC officials and two members of the Presidential Commission on the Space Shuttle Challenger Accident meet in the Executive Conference Room of JSC’s Project Management Building. Left to right are JSC Deputy Director Robert C. Goetz; Richard H. Kohrs, Deputy Manager for National Space Transportation Systems Program Office; and commission members Joseph F. Sutter and Dr. Arthur B.C. Walker Jr. Photo credit: NASA

  16. Comparison of cumulant expansion and q-space imaging estimates for diffusional kurtosis in brain.

    PubMed

    Mohanty, Vaibhav; McKinnon, Emilie T; Helpern, Joseph A; Jensen, Jens H

    2018-05-01

    To compare estimates for the diffusional kurtosis in brain as obtained from a cumulant expansion (CE) of the diffusion MRI (dMRI) signal and from q-space (QS) imaging. For the CE estimates of the kurtosis, the CE was truncated to quadratic order in the b-value and fit to the dMRI signal for b-values from 0 up to 2000s/mm 2 . For the QS estimates, b-values ranging from 0 up to 10,000s/mm 2 were used to determine the diffusion displacement probability density function (dPDF) via Stejskal's formula. The kurtosis was then calculated directly from the second and fourth order moments of the dPDF. These two approximations were studied for in vivo human data obtained on a 3T MRI scanner using three orthogonal diffusion encoding directions. The whole brain mean values for the CE and QS kurtosis estimates differed by 16% or less in each of the considered diffusion encoding directions, and the Pearson correlation coefficients all exceeded 0.85. Nonetheless, there were large discrepancies in many voxels, particularly those with either very high or very low kurtoses relative to the mean values. Estimates of the diffusional kurtosis in brain obtained using CE and QS approximations are strongly correlated, suggesting that they encode similar information. However, for the choice of b-values employed here, there may be substantial differences, depending on the properties of the diffusion microenvironment in each voxel. Copyright © 2018 Elsevier Inc. All rights reserved.

  17. Estimation of the Mean Axon Diameter and Intra-axonal Space Volume Fraction of the Human Corpus Callosum: Diffusion q-space Imaging with Low q-values.

    PubMed

    Suzuki, Yuriko; Hori, Masaaki; Kamiya, Kouhei; Fukunaga, Issei; Aoki, Shigeki; VAN Cauteren, Marc

    2016-01-01

    Q-space imaging (QSI) is a diffusion-weighted imaging (DWI) technique that enables investigation of tissue microstructure. However, for sufficient displacement resolution to measure the microstructure, QSI requires high q-values that are usually difficult to achieve with a clinical scanner. The recently introduced "low q-value method" fits the echo attenuation to only low q-values to extract the root mean square displacement. We investigated the clinical feasibility of the low q-value method for estimating the microstructure of the human corpus callosum using a 3.0-tesla clinical scanner within a clinically feasible scan time. We performed a simulation to explore the acceptable range of maximum q-values for the low q-value method. We simulated echo attenuations caused by restricted diffusion in the intra-axonal space (IAS) and hindered diffusion in the extra-axonal space (EAS) assuming 100,000 cylinders with various diameters, and we estimated mean axon diameter, IAS volume fraction, and EAS diffusivity by fitting echo attenuations with different maximum q-values. Furthermore, we scanned the corpus callosum of 7 healthy volunteers and estimated the mean axon diameter and IAS volume fraction. Good agreement between estimated and defined values in the simulation study with maximum q-values of 700 and 800 cm(-1) suggested that the maximum q-value used in the in vivo experiment, 737 cm(-1), was reasonable. In the in vivo experiment, the mean axon diameter was larger in the body of the corpus callosum and smaller in the genu and splenium, and this anterior-to-posterior trend is consistent with previously reported histology, although our mean axon diameter seems larger in size. On the other hand, we found an opposite anterior-to-posterior trend, with high IAS volume fraction in the genu and splenium and a lower fraction in the body, which is similar to the fiber density reported in the histology study. The low q-value method may provide insights into tissue

  18. IDH mutant and 1p/19q co-deleted oligodendrogliomas: tumor grade stratification using diffusion-, susceptibility-, and perfusion-weighted MRI.

    PubMed

    Lin, Yu; Xing, Zhen; She, Dejun; Yang, Xiefeng; Zheng, Yingyan; Xiao, Zebin; Wang, Xingfu; Cao, Dairong

    2017-06-01

    Currently, isocitrate dehydrogenase (IDH) mutation and 1p/19q co-deletion are proven diagnostic biomarkers for both grade II and III oligodendrogliomas (ODs). Non-invasive diffusion-weighted imaging (DWI), susceptibility-weighted imaging (SWI), and dynamic susceptibility contrast perfusion-weighted imaging (DSC-PWI) are widely used to provide physiological information (cellularity, hemorrhage, calcifications, and angiogenesis) of neoplastic histology and tumor grade. However, it is unclear whether DWI, SWI, and DSC-PWI are able to stratify grades of IDH-mutant and 1p/19q co-deleted ODs. We retrospectively reviewed the conventional MRI (cMRI), DWI, SWI, and DSC-PWI obtained on 33 patients with IDH-mutated and 1p/19q co-deleted ODs. Features of cMRI, normalized ADC (nADC), intratumoral susceptibility signals (ITSSs), normalized maxim CBV (nCBV), and normalized maximum CBF (nCBF) were compared between low-grade ODs (LGOs) and high-grade ODs (HGOs). Receiver operating characteristic curve and logistic regression were applied to determine diagnostic performances. HGOs tended to present with prominent edema and enhancement. nADC, ITSSs, nCBV, and nCBF were significantly different between groups (all P < 0.05). The combination of SWI and DSC-PWI for grading resulted in sensitivity and specificity of 100.00 and 93.33%, respectively. IDH-mutant and 1p/19q co-deleted ODs can be stratified by grades using cMRI and advanced magnetic resonance imaging techniques including DWI, SWI, and DSC-PWI. Combined ITSSs with nCBV appear to be a promising option for grading molecularly defined ODs in clinical practice.

  19. Q-Space Truncation and Sampling in Diffusion Spectrum Imaging

    PubMed Central

    Tian, Qiyuan; Rokem, Ariel; Folkerth, Rebecca D.; Nummenmaa, Aapo; Fan, Qiuyun; Edlow, Brian L.; McNab, Jennifer A.

    2015-01-01

    Purpose To characterize the q-space truncation and sampling on the spin-displacement probability density function (PDF) in diffusion spectrum imaging (DSI). Methods DSI data were acquired using the MGH-USC connectome scanner (Gmax=300mT/m) with bmax=30,000s/mm2, 17×17×17, 15×15×15 and 11×11×11 grids in ex vivo human brains and bmax=10,000s/mm2, 11×11×11 grid in vivo. An additional in vivo scan using bmax=7,000s/mm2, 11×11×11 grid was performed with a derated gradient strength of 40mT/m. PDFs and orientation distribution functions (ODFs) were reconstructed with different q-space filtering and PDF integration lengths, and from down-sampled data by factors of two and three. Results Both ex vivo and in vivo data showed Gibbs ringing in PDFs, which becomes the main source of artifact in the subsequently reconstructed ODFs. For down-sampled data, PDFs interfere with the first replicas or their ringing, leading to obscured orientations in ODFs. Conclusion The minimum required q-space sampling density corresponds to a field-of-view approximately equal to twice the mean displacement distance (MDD) of the tissue. The 11×11×11 grid is suitable for both ex vivo and in vivo DSI experiments. To minimize the effects of Gibbs ringing, ODFs should be reconstructed from unfiltered q-space data with the integration length over the PDF constrained to around the MDD. PMID:26762670

  20. Wavelet-space correlation imaging for high-speed MRI without motion monitoring or data segmentation.

    PubMed

    Li, Yu; Wang, Hui; Tkach, Jean; Roach, David; Woods, Jason; Dumoulin, Charles

    2015-12-01

    This study aims to (i) develop a new high-speed MRI approach by implementing correlation imaging in wavelet-space, and (ii) demonstrate the ability of wavelet-space correlation imaging to image human anatomy with involuntary or physiological motion. Correlation imaging is a high-speed MRI framework in which image reconstruction relies on quantification of data correlation. The presented work integrates correlation imaging with a wavelet transform technique developed originally in the field of signal and image processing. This provides a new high-speed MRI approach to motion-free data collection without motion monitoring or data segmentation. The new approach, called "wavelet-space correlation imaging", is investigated in brain imaging with involuntary motion and chest imaging with free-breathing. Wavelet-space correlation imaging can exceed the speed limit of conventional parallel imaging methods. Using this approach with high acceleration factors (6 for brain MRI, 16 for cardiac MRI, and 8 for lung MRI), motion-free images can be generated in static brain MRI with involuntary motion and nonsegmented dynamic cardiac/lung MRI with free-breathing. Wavelet-space correlation imaging enables high-speed MRI in the presence of involuntary motion or physiological dynamics without motion monitoring or data segmentation. © 2014 Wiley Periodicals, Inc.

  1. Wavelet-space Correlation Imaging for High-speed MRI without Motion Monitoring or Data Segmentation

    PubMed Central

    Li, Yu; Wang, Hui; Tkach, Jean; Roach, David; Woods, Jason; Dumoulin, Charles

    2014-01-01

    Purpose This study aims to 1) develop a new high-speed MRI approach by implementing correlation imaging in wavelet-space, and 2) demonstrate the ability of wavelet-space correlation imaging to image human anatomy with involuntary or physiological motion. Methods Correlation imaging is a high-speed MRI framework in which image reconstruction relies on quantification of data correlation. The presented work integrates correlation imaging with a wavelet transform technique developed originally in the field of signal and image processing. This provides a new high-speed MRI approach to motion-free data collection without motion monitoring or data segmentation. The new approach, called “wavelet-space correlation imaging”, is investigated in brain imaging with involuntary motion and chest imaging with free-breathing. Results Wavelet-space correlation imaging can exceed the speed limit of conventional parallel imaging methods. Using this approach with high acceleration factors (6 for brain MRI, 16 for cardiac MRI and 8 for lung MRI), motion-free images can be generated in static brain MRI with involuntary motion and nonsegmented dynamic cardiac/lung MRI with free-breathing. Conclusion Wavelet-space correlation imaging enables high-speed MRI in the presence of involuntary motion or physiological dynamics without motion monitoring or data segmentation. PMID:25470230

  2. Advances in locally constrained k-space-based parallel MRI.

    PubMed

    Samsonov, Alexey A; Block, Walter F; Arunachalam, Arjun; Field, Aaron S

    2006-02-01

    In this article, several theoretical and methodological developments regarding k-space-based, locally constrained parallel MRI (pMRI) reconstruction are presented. A connection between Parallel MRI with Adaptive Radius in k-Space (PARS) and GRAPPA methods is demonstrated. The analysis provides a basis for unified treatment of both methods. Additionally, a weighted PARS reconstruction is proposed, which may absorb different weighting strategies for improved image reconstruction. Next, a fast and efficient method for pMRI reconstruction of data sampled on non-Cartesian trajectories is described. In the new technique, the computational burden associated with the numerous matrix inversions in the original PARS method is drastically reduced by limiting direct calculation of reconstruction coefficients to only a few reference points. The rest of the coefficients are found by interpolating between the reference sets, which is possible due to the similar configuration of points participating in reconstruction for highly symmetric trajectories, such as radial and spirals. As a result, the time requirements are drastically reduced, which makes it practical to use pMRI with non-Cartesian trajectories in many applications. The new technique was demonstrated with simulated and actual data sampled on radial trajectories. Copyright 2006 Wiley-Liss, Inc.

  3. Feature space analysis of MRI

    NASA Astrophysics Data System (ADS)

    Soltanian-Zadeh, Hamid; Windham, Joe P.; Peck, Donald J.

    1997-04-01

    This paper presents development and performance evaluation of an MRI feature space method. The method is useful for: identification of tissue types; segmentation of tissues; and quantitative measurements on tissues, to obtain information that can be used in decision making (diagnosis, treatment planning, and evaluation of treatment). The steps of the work accomplished are as follows: (1) Four T2-weighted and two T1-weighted images (before and after injection of Gadolinium) were acquired for ten tumor patients. (2) Images were analyed by two image analysts according to the following algorithm. The intracranial brain tissues were segmented from the scalp and background. The additive noise was suppressed using a multi-dimensional non-linear edge- preserving filter which preserves partial volume information on average. Image nonuniformities were corrected using a modified lowpass filtering approach. The resulting images were used to generate and visualize an optimal feature space. Cluster centers were identified on the feature space. Then images were segmented into normal tissues and different zones of the tumor. (3) Biopsy samples were extracted from each patient and were subsequently analyzed by the pathology laboratory. (4) Image analysis results were compared to each other and to the biopsy results. Pre- and post-surgery feature spaces were also compared. The proposed algorithm made it possible to visualize the MRI feature space and to segment the image. In all cases, the operators were able to find clusters for normal and abnormal tissues. Also, clusters for different zones of the tumor were found. Based on the clusters marked for each zone, the method successfully segmented the image into normal tissues (white matter, gray matter, and CSF) and different zones of the lesion (tumor, cyst, edema, radiation necrosis, necrotic core, and infiltrated tumor). The results agreed with those obtained from the biopsy samples. Comparison of pre- to post-surgery and radiation

  4. Actions to implement the recommendations of the Presidential Commission on the Space Shuttle Challenger Accident. Report to the President

    NASA Technical Reports Server (NTRS)

    1986-01-01

    The status of the implementation of the recommendations of the Presidential Commission on the Space Shuttle Challenger Accident is reported. The implementation of recommendations in the following areas is detailed: (1) solid rocket motor design; (2) shuttle management structure, including the shuttle safety panel and astronauts in management; (3) critical item review and hazard analysis; (4) safety organization; (5) improved communication; (6) landing safety; (7) launch abort and crew escape; (8) flight rate; and (9) maintenance safeguards. Supporting memoranda and communications from NASA are appended.

  5. Symposium on Presidential Libraries.

    ERIC Educational Resources Information Center

    Relyea, Harold C.; And Others

    1994-01-01

    Includes five articles that discuss presidential libraries. Highlights include an overview of the development of the federal presidential library system; the Ronald Reagan library; the Richard Nixon library archives; access at the Gerald Ford library; and computerizing the Jimmy Carter library. (LRW)

  6. Q-space truncation and sampling in diffusion spectrum imaging.

    PubMed

    Tian, Qiyuan; Rokem, Ariel; Folkerth, Rebecca D; Nummenmaa, Aapo; Fan, Qiuyun; Edlow, Brian L; McNab, Jennifer A

    2016-12-01

    To characterize the q-space truncation and sampling on the spin-displacement probability density function (PDF) in diffusion spectrum imaging (DSI). DSI data were acquired using the MGH-USC connectome scanner (G max  = 300 mT/m) with b max  = 30,000 s/mm 2 , 17 × 17 × 17, 15 × 15 × 15 and 11 × 11 × 11 grids in ex vivo human brains and b max  = 10,000 s/mm 2 , 11 × 11 × 11 grid in vivo. An additional in vivo scan using b max =7,000 s/mm 2 , 11 × 11 × 11 grid was performed with a derated gradient strength of 40 mT/m. PDFs and orientation distribution functions (ODFs) were reconstructed with different q-space filtering and PDF integration lengths, and from down-sampled data by factors of two and three. Both ex vivo and in vivo data showed Gibbs ringing in PDFs, which becomes the main source of artifact in the subsequently reconstructed ODFs. For down-sampled data, PDFs interfere with the first replicas or their ringing, leading to obscured orientations in ODFs. The minimum required q-space sampling density corresponds to a field-of-view approximately equal to twice the mean displacement distance (MDD) of the tissue. The 11 × 11 × 11 grid is suitable for both ex vivo and in vivo DSI experiments. To minimize the effects of Gibbs ringing, ODFs should be reconstructed from unfiltered q-space data with the integration length over the PDF constrained to around the MDD. Magn Reson Med 76:1750-1763, 2016. © 2016 International Society for Magnetic Resonance in Medicine. © 2016 International Society for Magnetic Resonance in Medicine.

  7. Mean apparent propagator (MAP) MRI: a novel diffusion imaging method for mapping tissue microstructure.

    PubMed

    Özarslan, Evren; Koay, Cheng Guan; Shepherd, Timothy M; Komlosh, Michal E; İrfanoğlu, M Okan; Pierpaoli, Carlo; Basser, Peter J

    2013-09-01

    Diffusion-weighted magnetic resonance (MR) signals reflect information about underlying tissue microstructure and cytoarchitecture. We propose a quantitative, efficient, and robust mathematical and physical framework for representing diffusion-weighted MR imaging (MRI) data obtained in "q-space," and the corresponding "mean apparent propagator (MAP)" describing molecular displacements in "r-space." We also define and map novel quantitative descriptors of diffusion that can be computed robustly using this MAP-MRI framework. We describe efficient analytical representation of the three-dimensional q-space MR signal in a series expansion of basis functions that accurately describes diffusion in many complex geometries. The lowest order term in this expansion contains a diffusion tensor that characterizes the Gaussian displacement distribution, equivalent to diffusion tensor MRI (DTI). Inclusion of higher order terms enables the reconstruction of the true average propagator whose projection onto the unit "displacement" sphere provides an orientational distribution function (ODF) that contains only the orientational dependence of the diffusion process. The representation characterizes novel features of diffusion anisotropy and the non-Gaussian character of the three-dimensional diffusion process. Other important measures this representation provides include the return-to-the-origin probability (RTOP), and its variants for diffusion in one- and two-dimensions-the return-to-the-plane probability (RTPP), and the return-to-the-axis probability (RTAP), respectively. These zero net displacement probabilities measure the mean compartment (pore) volume and cross-sectional area in distributions of isolated pores irrespective of the pore shape. MAP-MRI represents a new comprehensive framework to model the three-dimensional q-space signal and transform it into diffusion propagators. Experiments on an excised marmoset brain specimen demonstrate that MAP-MRI provides several novel

  8. 76 FR 11337 - Presidential Library Facilities; Correction

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-02

    ... Presidential Library Facilities; Correction AGENCY: National Archives and Records Administration. ACTION... and design standards for Presidential libraries and information required in NARA's reports to Congress... Presidential library. DATES: This regulation is effective March 2, 2011. FOR FURTHER INFORMATION CONTACT: Laura...

  9. Mitochondria‐targeted antioxidant MitoQ reduced renal damage caused by ischemia‐reperfusion injury in rodent kidneys: Longitudinal observations of T 2‐weighted imaging and dynamic contrast‐enhanced MRI

    PubMed Central

    Liu, Xiaoge; Murphy, Michael P.; Xing, Wei; Wu, Huanhuan; Zhang, Rui

    2017-01-01

    Purpose To investigate the effect of mitochondria‐targeted antioxidant MitoQ in reducing the severity of renal ischemia‐reperfusion injury (IRI) in rats using T2‐weighted imaging and dynamic contrast‐enhanced MRI (DCE‐MRI). Methods Ischemia‐reperfusion injury was induced by temporarily clamping the left renal artery. Rats were pretreated with MitoQ or saline. The MRI examination was performed before and after IRI (days 2, 5, 7, and 14). The T2‐weighted standardized signal intensity of the outer stripe of the outer medulla (OSOM) was measured. The unilateral renal clearance rate kcl was derived from DCE‐MRI. Histopathology was evaluated after the final MRI examination. Results The standardized signal intensity of the OSOM on IRI kidneys with MitoQ were lower than those with saline on days 5 and 7 (P = 0.004, P < 0.001, respectively). Kcl values of IRI kidneys with MitoQ were higher than those with saline at all time points (P = 0.002, P < 0.001, P = 0.001, P < 0.001). Histopathology showed that renal damage was the most predominant on the OSOM of IRI kidneys with saline, which was less obvious with MitoQ (P < 0.001). Conclusions These findings demonstrate that MitoQ can reduce the severity of renal damage in rodent IRI models using T2‐weighted imaging and DCE‐MRI. Magn Reson Med 79:1559–1667, 2018. © 2017 The Authors Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. PMID:28608403

  10. Functional feature embedded space mapping of fMRI data.

    PubMed

    Hu, Jin; Tian, Jie; Yang, Lei

    2006-01-01

    We have proposed a new method for fMRI data analysis which is called Functional Feature Embedded Space Mapping (FFESM). Our work mainly focuses on the experimental design with periodic stimuli which can be described by a number of Fourier coefficients in the frequency domain. A nonlinear dimension reduction technique Isomap is applied to the high dimensional features obtained from frequency domain of the fMRI data for the first time. Finally, the presence of activated time series is identified by the clustering method in which the information theoretic criterion of minimum description length (MDL) is used to estimate the number of clusters. The feasibility of our algorithm is demonstrated by real human experiments. Although we focus on analyzing periodic fMRI data, the approach can be extended to analyze non-periodic fMRI data (event-related fMRI) by replacing the Fourier analysis with a wavelet analysis.

  11. Complete integrability of geodesic motion in Sasaki-Einstein toric Yp,q spaces

    NASA Astrophysics Data System (ADS)

    Babalic, Elena Mirela; Visinescu, Mihai

    2015-09-01

    We construct explicitly the constants of motion for geodesics in the five-dimensional Sasaki-Einstein spaces Yp,q. To carry out this task, we use the knowledge of the complete set of Killing vectors and Killing-Yano tensors on these spaces. In spite of the fact that we generate a multitude of constants of motion, only five of them are functionally independent implying the complete integrability of geodesic flow on Yp,q spaces. In the particular case of the homogeneous Sasaki-Einstein manifold T1,1 the integrals of motion have simpler forms and the relations between them are described in detail.

  12. Mitochondria-targeted antioxidant MitoQ reduced renal damage caused by ischemia-reperfusion injury in rodent kidneys: Longitudinal observations of T2 -weighted imaging and dynamic contrast-enhanced MRI.

    PubMed

    Liu, Xiaoge; Murphy, Michael P; Xing, Wei; Wu, Huanhuan; Zhang, Rui; Sun, Haoran

    2018-03-01

    To investigate the effect of mitochondria-targeted antioxidant MitoQ in reducing the severity of renal ischemia-reperfusion injury (IRI) in rats using T 2 -weighted imaging and dynamic contrast-enhanced MRI (DCE-MRI). Ischemia-reperfusion injury was induced by temporarily clamping the left renal artery. Rats were pretreated with MitoQ or saline. The MRI examination was performed before and after IRI (days 2, 5, 7, and 14). The T 2 -weighted standardized signal intensity of the outer stripe of the outer medulla (OSOM) was measured. The unilateral renal clearance rate k cl was derived from DCE-MRI. Histopathology was evaluated after the final MRI examination. The standardized signal intensity of the OSOM on IRI kidneys with MitoQ were lower than those with saline on days 5 and 7 (P = 0.004, P < 0.001, respectively). K cl values of IRI kidneys with MitoQ were higher than those with saline at all time points (P = 0.002, P < 0.001, P = 0.001, P < 0.001). Histopathology showed that renal damage was the most predominant on the OSOM of IRI kidneys with saline, which was less obvious with MitoQ (P < 0.001). These findings demonstrate that MitoQ can reduce the severity of renal damage in rodent IRI models using T 2 -weighted imaging and DCE-MRI. Magn Reson Med 79:1559-1667, 2018. © 2017 The Authors Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. © 2017 The Authors Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine.

  13. Correlations of Behavioral Deficits with Brain Pathology Assessed through Longitudinal MRI and Histopathology in the HdhQ150/Q150 Mouse Model of Huntington’s Disease

    PubMed Central

    Rattray, Ivan; Smith, Edward J.; Crum, William R.; Walker, Thomas A.; Gale, Richard; Bates, Gillian P.

    2017-01-01

    A variety of mouse models have been developed that express mutant huntingtin (mHTT) leading to aggregates and inclusions that model the molecular pathology observed in Huntington’s disease. Here we show that although homozygous HdhQ150 knock-in mice developed motor impairments (rotarod, locomotor activity, grip strength) by 36 weeks of age, cognitive dysfunction (swimming T maze, fear conditioning, odor discrimination, social interaction) was not evident by 94 weeks. Concomitant to behavioral assessments, T2-weighted MRI volume measurements indicated a slower striatal growth with a significant difference between wild type (WT) and HdhQ150 mice being present even at 15 weeks. Indeed, MRI indicated significant volumetric changes prior to the emergence of the “clinical horizon” of motor impairments at 36 weeks of age. A striatal decrease of 27% was observed over 94 weeks with cortex (12%) and hippocampus (21%) also indicating significant atrophy. A hypothesis-free analysis using tensor-based morphometry highlighted further regions undergoing atrophy by contrasting brain growth and regional neurodegeneration. Histology revealed the widespread presence of mHTT aggregates and cellular inclusions. However, there was little evidence of correlations between these outcome measures, potentially indicating that other factors are important in the causal cascade linking the molecular pathology to the emergence of behavioral impairments. In conclusion, the HdhQ150 mouse model replicates many aspects of the human condition, including an extended pre-manifest period prior to the emergence of motor impairments. PMID:28099507

  14. Presidential Transitions during Capital Campaigns

    ERIC Educational Resources Information Center

    Nehls, Kimberly

    2008-01-01

    In the past few decades, capital campaigns at institutions of higher education have increased in duration, while collegiate presidential tenures have been doing just the opposite. Turnover in the top post was frequent, even during major fundraising campaigns. Before this study, presidential transitions during campaigns had not been previously…

  15. Non-invasive quantitative pulmonary V/Q imaging using Fourier decomposition MRI at 1.5T.

    PubMed

    Kjørstad, Åsmund; Corteville, Dominique M R; Henzler, Thomas; Schmid-Bindert, Gerald; Zöllner, Frank G; Schad, Lothar R

    2015-12-01

    Techniques for quantitative pulmonary perfusion and ventilation using the Fourier Decomposition method were recently demonstrated. We combine these two techniques and show that ventilation-perfusion (V/Q) imaging is possible using only a single MR acquisition of less than thirty seconds. The Fourier Decomposition method is used in combination with two quantification techniques, which extract baselines from within the images themselves and thus allows quantification. For the perfusion, a region assumed to consist of 100% blood is utilized, while for the ventilation the zero-frequency component is used. V/Q-imaging is then done by dividing the quantified ventilation map with the quantified perfusion map. The techniques were used on ten healthy volunteers and fifteen patients diagnosed with lung cancer. A mean V/Q-ratio of 1.15 ± 0.22 was found for the healthy volunteers and a mean V/Q-ratio of 1.93 ± 0.83 for the non-afflicted lung in the patients. Mean V/Q-ratio in the afflicted (tumor-bearing) lung was found to be 1.61 ± 1.06. Functional defects were clearly visible in many of the patient images, but 5 of 15 patient images had to be excluded due to artifacts or low SNR, indicating a lack of robustness. Non-invasive, quantitative V/Q-imaging is possible using Fourier Decomposition MRI. The method requires only a single acquisition of less than 30 seconds, but robustness in patients remains an issue. Copyright © 2015. Published by Elsevier GmbH.

  16. MRI-visible perivascular space location is associated with Alzheimer's disease independently of amyloid burden.

    PubMed

    Banerjee, Gargi; Kim, Hee Jin; Fox, Zoe; Jäger, H Rolf; Wilson, Duncan; Charidimou, Andreas; Na, Han Kyu; Na, Duk L; Seo, Sang Won; Werring, David J

    2017-04-01

    Perivascular spaces that are visible on magnetic resonance imaging (MRI) are a neuroimaging marker of cerebral small vessel disease. Their location may relate to the type of underlying small vessel pathology: those in the white matter centrum semi-ovale have been associated with cerebral amyloid angiopathy, while those in the basal ganglia have been associated with deep perforating artery arteriolosclerosis. As cerebral amyloid angiopathy is an almost invariable pathological finding in Alzheimer's disease, we hypothesized that MRI-visible perivascular spaces in the centrum semi-ovale would be associated with a clinical diagnosis of Alzheimer's disease, whereas those in the basal ganglia would be associated with subcortical vascular cognitive impairment. We also hypothesized that MRI-visible perivascular spaces in the centrum semi-ovale would be associated with brain amyloid burden, as detected by amyloid positron emission tomography using 11C-Pittsburgh B compound (PiB-PET). Two hundred and twenty-six patients (Alzheimer's disease n = 110; subcortical vascular cognitive impairment n = 116) with standardized MRI and PiB-PET imaging were included. MRI-visible perivascular spaces were rated using a validated 4-point visual rating scale, and then categorized by severity ('none/mild', 'moderate' or 'frequent/severe'). Univariable and multivariable regression analyses were performed. Those with Alzheimer's disease-related cognitive impairment were younger, more likely to have a positive PiB-PET scan and carry at least one apolipoprotein E ɛ4 allele; those with subcortical vascular cognitive impairment were more likely to have hypertension, diabetes mellitus, hyperlipidaemia, prior stroke, lacunes, deep microbleeds, and carry the apolipoprotein E ɛ3 allele. In adjusted analyses, the severity of MRI-visible perivascular spaces in the centrum semi-ovale was independently associated with clinically diagnosed Alzheimer's disease (frequent/severe grade odds ratio 6.26, 95

  17. 26 CFR 701.9006-1 - Presidential Election Campaign Fund.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 20 2010-04-01 2010-04-01 false Presidential Election Campaign Fund. 701.9006-1...) INTERNAL REVENUE PRACTICE PRESIDENTIAL ELECTION CAMPAIGN FUND § 701.9006-1 Presidential Election Campaign Fund. (a) Transfer of amounts to the Presidential Election Campaign Fund. The Secretary shall determine...

  18. q-Space Deep Learning: Twelve-Fold Shorter and Model-Free Diffusion MRI Scans.

    PubMed

    Golkov, Vladimir; Dosovitskiy, Alexey; Sperl, Jonathan I; Menzel, Marion I; Czisch, Michael; Samann, Philipp; Brox, Thomas; Cremers, Daniel

    2016-05-01

    Numerous scientific fields rely on elaborate but partly suboptimal data processing pipelines. An example is diffusion magnetic resonance imaging (diffusion MRI), a non-invasive microstructure assessment method with a prominent application in neuroimaging. Advanced diffusion models providing accurate microstructural characterization so far have required long acquisition times and thus have been inapplicable for children and adults who are uncooperative, uncomfortable, or unwell. We show that the long scan time requirements are mainly due to disadvantages of classical data processing. We demonstrate how deep learning, a group of algorithms based on recent advances in the field of artificial neural networks, can be applied to reduce diffusion MRI data processing to a single optimized step. This modification allows obtaining scalar measures from advanced models at twelve-fold reduced scan time and detecting abnormalities without using diffusion models. We set a new state of the art by estimating diffusion kurtosis measures from only 12 data points and neurite orientation dispersion and density measures from only 8 data points. This allows unprecedentedly fast and robust protocols facilitating clinical routine and demonstrates how classical data processing can be streamlined by means of deep learning.

  19. Leveraging EAP-Sparsity for Compressed Sensing of MS-HARDI in (k, q)-Space.

    PubMed

    Sun, Jiaqi; Sakhaee, Elham; Entezari, Alireza; Vemuri, Baba C

    2015-01-01

    Compressed Sensing (CS) for the acceleration of MR scans has been widely investigated in the past decade. Lately, considerable progress has been made in achieving similar speed ups in acquiring multi-shell high angular resolution diffusion imaging (MS-HARDI) scans. Existing approaches in this context were primarily concerned with sparse reconstruction of the diffusion MR signal S(q) in the q-space. More recently, methods have been developed to apply the compressed sensing framework to the 6-dimensional joint (k, q)-space, thereby exploiting the redundancy in this 6D space. To guarantee accurate reconstruction from partial MS-HARDI data, the key ingredients of compressed sensing that need to be brought together are: (1) the function to be reconstructed needs to have a sparse representation, and (2) the data for reconstruction ought to be acquired in the dual domain (i.e., incoherent sensing) and (3) the reconstruction process involves a (convex) optimization. In this paper, we present a novel approach that uses partial Fourier sensing in the 6D space of (k, q) for the reconstruction of P(x, r). The distinct feature of our approach is a sparsity model that leverages surfacelets in conjunction with total variation for the joint sparse representation of P(x, r). Thus, our method stands to benefit from the practical guarantees for accurate reconstruction from partial (k, q)-space data. Further, we demonstrate significant savings in acquisition time over diffusion spectral imaging (DSI) which is commonly used as the benchmark for comparisons in reported literature. To demonstrate the benefits of this approach,.we present several synthetic and real data examples.

  20. Respiratory motion resolved, self-gated 4D-MRI using Rotating Cartesian K-space (ROCK)

    PubMed Central

    Han, Fei; Zhou, Ziwu; Cao, Minsong; Yang, Yingli; Sheng, Ke; Hu, Peng

    2017-01-01

    Purpose To propose and validate a respiratory motion resolved, self-gated (SG) 4D-MRI technique to assess patient-specific breathing motion of abdominal organs for radiation treatment planning. Methods The proposed 4D-MRI technique was based on the balanced steady-state free-precession (bSSFP) technique and 3D k-space encoding. A novel ROtating Cartesian K-space (ROCK) reordering method was designed that incorporates repeatedly sampled k-space centerline as the SG motion surrogate and allows for retrospective k-space data binning into different respiratory positions based on the amplitude of the surrogate. The multiple respiratory-resolved 3D k-space data were subsequently reconstructed using a joint parallel imaging and compressed sensing method with spatial and temporal regularization. The proposed 4D-MRI technique was validated using a custom-made dynamic motion phantom and was tested in 6 healthy volunteers, in whom quantitative diaphragm and kidney motion measurements based on 4D-MRI images were compared with those based on 2D-CINE images. Results The 5-minute 4D-MRI scan offers high-quality volumetric images in 1.2×1.2×1.6mm3 and 8 respiratory positions, with good soft-tissue contrast. In phantom experiments with triangular motion waveform, the motion amplitude measurements based on 4D-MRI were 11.89% smaller than the ground truth, whereas a −12.5% difference was expected due to data binning effects. In healthy volunteers, the difference between the measurements based on 4D-MRI and the ones based on 2D-CINE were 6.2±4.5% for the diaphragm, 8.2±4.9% and 8.9±5.1% for the right and left kidney. Conclusion The proposed 4D-MRI technique could provide high resolution, high quality, respiratory motion resolved 4D images with good soft-tissue contrast and are free of the “stitching” artifacts usually seen on 4D-CT and 4D-MRI based on resorting 2D-CINE. It could be used to visualize and quantify abdominal organ motion for MRI-based radiation treatment

  1. Respiratory motion-resolved, self-gated 4D-MRI using rotating cartesian k-space (ROCK).

    PubMed

    Han, Fei; Zhou, Ziwu; Cao, Minsong; Yang, Yingli; Sheng, Ke; Hu, Peng

    2017-04-01

    To propose and validate a respiratory motion resolved, self-gated (SG) 4D-MRI technique to assess patient-specific breathing motion of abdominal organs for radiation treatment planning. The proposed 4D-MRI technique was based on the balanced steady-state free-precession (bSSFP) technique and 3D k-space encoding. A novel rotating cartesian k-space (ROCK) reordering method was designed which incorporates repeatedly sampled k-space centerline as the SG motion surrogate and allows for retrospective k-space data binning into different respiratory positions based on the amplitude of the surrogate. The multiple respiratory-resolved 3D k-space data were subsequently reconstructed using a joint parallel imaging and compressed sensing method with spatial and temporal regularization. The proposed 4D-MRI technique was validated using a custom-made dynamic motion phantom and was tested in six healthy volunteers, in whom quantitative diaphragm and kidney motion measurements based on 4D-MRI images were compared with those based on 2D-CINE images. The 5-minute 4D-MRI scan offers high-quality volumetric images in 1.2 × 1.2 × 1.6 mm 3 and eight respiratory positions, with good soft-tissue contrast. In phantom experiments with triangular motion waveform, the motion amplitude measurements based on 4D-MRI were 11.89% smaller than the ground truth, whereas a -12.5% difference was expected due to data binning effects. In healthy volunteers, the difference between the measurements based on 4D-MRI and the ones based on 2D-CINE were 6.2 ± 4.5% for the diaphragm, 8.2 ± 4.9% and 8.9 ± 5.1% for the right and left kidney. The proposed 4D-MRI technique could provide high-resolution, high-quality, respiratory motion-resolved 4D images with good soft-tissue contrast and are free of the "stitching" artifacts usually seen on 4D-CT and 4D-MRI based on resorting 2D-CINE. It could be used to visualize and quantify abdominal organ motion for MRI-based radiation treatment planning. © 2017 American

  2. 5 CFR 317.703 - Guaranteed reinstatement: Presidential appointees.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... service, and who left the Presidential appointment for reasons other than misconduct, neglect of duty, or... same or a new agency, must be reinstated to an appropriate position as an SES career appointee before the effective date of the new Presidential appointment, unless service as a Presidential appointee...

  3. q-Deformed Minkowski Algebra and Its Space-Time Lattice

    NASA Astrophysics Data System (ADS)

    Wess, J.

    2Max-Planck-Institut für Physik (Werner-Heisenberg-Institut) Föhringer Ring 6, D-80805 MünchenAbstract. We have asked how the Heisenberg relations of space and time change if we replace the Lorentz group by a q-deformed Lorentz group (Lorek et al. 1997).

  4. Application of Quantitative MRI for Brain Tissue Segmentation at 1.5 T and 3.0 T Field Strengths

    PubMed Central

    West, Janne; Blystad, Ida; Engström, Maria; Warntjes, Jan B. M.; Lundberg, Peter

    2013-01-01

    Background Brain tissue segmentation of white matter (WM), grey matter (GM), and cerebrospinal fluid (CSF) are important in neuroradiological applications. Quantitative Mri (qMRI) allows segmentation based on physical tissue properties, and the dependencies on MR scanner settings are removed. Brain tissue groups into clusters in the three dimensional space formed by the qMRI parameters R1, R2 and PD, and partial volume voxels are intermediate in this space. The qMRI parameters, however, depend on the main magnetic field strength. Therefore, longitudinal studies can be seriously limited by system upgrades. The aim of this work was to apply one recently described brain tissue segmentation method, based on qMRI, at both 1.5 T and 3.0 T field strengths, and to investigate similarities and differences. Methods In vivo qMRI measurements were performed on 10 healthy subjects using both 1.5 T and 3.0 T MR scanners. The brain tissue segmentation method was applied for both 1.5 T and 3.0 T and volumes of WM, GM, CSF and brain parenchymal fraction (BPF) were calculated on both field strengths. Repeatability was calculated for each scanner and a General Linear Model was used to examine the effect of field strength. Voxel-wise t-tests were also performed to evaluate regional differences. Results Statistically significant differences were found between 1.5 T and 3.0 T for WM, GM, CSF and BPF (p<0.001). Analyses of main effects showed that WM was underestimated, while GM and CSF were overestimated on 1.5 T compared to 3.0 T. The mean differences between 1.5 T and 3.0 T were -66 mL WM, 40 mL GM, 29 mL CSF and -1.99% BPF. Voxel-wise t-tests revealed regional differences of WM and GM in deep brain structures, cerebellum and brain stem. Conclusions Most of the brain was identically classified at the two field strengths, although some regional differences were observed. PMID:24066153

  5. 46 CFR 565.11 - Presidential review.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 9 2010-10-01 2010-10-01 false Presidential review. 565.11 Section 565.11 Shipping FEDERAL MARITIME COMMISSION REGULATIONS AND ACTIONS TO ADDRESS RESTRICTIVE FOREIGN MARITIME PRACTICES CONTROLLED CARRIERS § 565.11 Presidential review. The Commission shall transmit all orders of suspension or...

  6. 75 FR 19662 - Advisory Committee on Presidential Libraries Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-15

    ... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Advisory Committee on Presidential Libraries Meeting... Records Administration (NARA) announces a meeting of the Advisory Committee on Presidential Libraries. The meeting will be held to discuss the Presidential Library program and topics related to the public-private...

  7. 14 CFR 91.141 - Flight restrictions in the proximity of the Presidential and other parties.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 2 2011-01-01 2011-01-01 false Flight restrictions in the proximity of the Presidential and other parties. 91.141 Section 91.141 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... parties. No person may operate an aircraft over or in the vicinity of any area to be visited or traveled...

  8. 14 CFR 91.141 - Flight restrictions in the proximity of the Presidential and other parties.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Flight restrictions in the proximity of the Presidential and other parties. 91.141 Section 91.141 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... parties. No person may operate an aircraft over or in the vicinity of any area to be visited or traveled...

  9. 14 CFR 91.141 - Flight restrictions in the proximity of the Presidential and other parties.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 2 2013-01-01 2013-01-01 false Flight restrictions in the proximity of the Presidential and other parties. 91.141 Section 91.141 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... parties. No person may operate an aircraft over or in the vicinity of any area to be visited or traveled...

  10. 14 CFR 91.141 - Flight restrictions in the proximity of the Presidential and other parties.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 2 2012-01-01 2012-01-01 false Flight restrictions in the proximity of the Presidential and other parties. 91.141 Section 91.141 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... parties. No person may operate an aircraft over or in the vicinity of any area to be visited or traveled...

  11. 14 CFR 91.141 - Flight restrictions in the proximity of the Presidential and other parties.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 2 2014-01-01 2014-01-01 false Flight restrictions in the proximity of the Presidential and other parties. 91.141 Section 91.141 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... parties. No person may operate an aircraft over or in the vicinity of any area to be visited or traveled...

  12. Teaching about Presidential Elections. ERIC Digest.

    ERIC Educational Resources Information Center

    Vontz, Thomas S.; Nixon, William A.

    Although elections are an annual theme in many social studies classrooms, presidential election years prompt increased interest among students in the electoral process and offer an opportunity to teach about a national election as it happens. This ERIC Digest describes the legal requirements and traditions of U.S. presidential elections, processes…

  13. A Space Affine Matching Approach to fMRI Time Series Analysis.

    PubMed

    Chen, Liang; Zhang, Weishi; Liu, Hongbo; Feng, Shigang; Chen, C L Philip; Wang, Huili

    2016-07-01

    For fMRI time series analysis, an important challenge is to overcome the potential delay between hemodynamic response signal and cognitive stimuli signal, namely the same frequency but different phase (SFDP) problem. In this paper, a novel space affine matching feature is presented by introducing the time domain and frequency domain features. The time domain feature is used to discern different stimuli, while the frequency domain feature to eliminate the delay. And then we propose a space affine matching (SAM) algorithm to match fMRI time series by our affine feature, in which a normal vector is estimated using gradient descent to explore the time series matching optimally. The experimental results illustrate that the SAM algorithm is insensitive to the delay between the hemodynamic response signal and the cognitive stimuli signal. Our approach significantly outperforms GLM method while there exists the delay. The approach can help us solve the SFDP problem in fMRI time series matching and thus of great promise to reveal brain dynamics.

  14. Presidential Leaks: Rhetoric and Mediated Political Knowledge.

    ERIC Educational Resources Information Center

    Erickson, Keith V.

    1989-01-01

    Argues that presidential leaks constitute rhetorical acts, enabling administrations to exercise a variety of rhetorically potent options not afforded by the public forum. Proposes a typology of presidential leaks and analyzes their rhetorical functions, benefits, and liabilities. (MM)

  15. 36 CFR 1253.3 - Presidential Libraries.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 2313 Red River St., Austin, TX 78705-5702. The phone number is 512-721-0200 and the fax number is 512... Presidential libraries are open for research from 9 a.m. to 5 p.m., Monday through Friday, except Federal... research. The Presidential library museums are open every day except Thanksgiving, December 25, and January...

  16. Us versus them: Political attitudes and party affiliation influence neural response to faces of presidential candidates.

    PubMed

    Kaplan, Jonas T; Freedman, Joshua; Iacoboni, Marco

    2007-01-07

    We investigated how political party affiliation and political attitudes modulate neural activity while viewing faces of presidential candidates. Ten registered Democrats and 10 registered Republicans were scanned in an event-related functional MRI paradigm while viewing pictures of the faces of George Bush, John Kerry, and Ralph Nader during the 2004 United States presidential campaign. We found that compared with viewing one's own candidate, viewing the candidate from the opposing political party produced signal changes in cognitive control circuitry in the dorsolateral prefrontal cortex and anterior cingulate, as well as in emotional regions such as the insula and anterior temporal poles. BOLD signal in these regions correlated with subjects' self-reported ratings of how they felt emotionally about the candidates. These data suggest that brain activity when viewing a politician's face is affected by the political allegiance of the viewer and that people regulate their emotional reactions to opposing candidates by activating cognitive control networks.

  17. 77 FR 42767 - Advisory Committee on Presidential Library-Foundation Partnerships

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-20

    ... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Advisory Committee on Presidential Library-Foundation... Presidential Library- Foundation Partnerships SUMMARY: This notice is published in accordance with the... Presidential Library-Foundation Partnerships. In accordance with Office of Management and Budget (OMB) Circular...

  18. 75 FR 42790 - Advisory Committee on Presidential Library-Foundation Partnerships.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-22

    ... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Advisory Committee on Presidential Library-Foundation... Presidential Library- Foundation Partnerships. SUMMARY: This notice is published in accordance with the... Presidential Library-Foundation Partnerships. In accordance with Office of Management and Budget (OMB) Circular...

  19. 77 FR 68153 - Advisory Committee on Presidential Library-Foundation Partnerships

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-15

    ... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Advisory Committee on Presidential Library-Foundation... Library-Foundation Partnerships. The meeting will be held to discuss the Presidential Library program and topics related to the public-private partnership between the Presidential Libraries and their...

  20. 76 FR 26317 - Advisory Committee on Presidential Library-Foundation Partnerships

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-06

    ... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Advisory Committee on Presidential Library-Foundation... Library-Foundation Partnerships. The meeting will be held to discuss the reorganization of the National Archives as they relate to Presidential Libraries, Social Media Initiatives, Processing of Presidential...

  1. The Role and Function of Presidential Libraries.

    ERIC Educational Resources Information Center

    Fischer, Linda

    This paper identifies various elements of presidential libraries. The advantages and disadvantages of the libraries' centralization or decentralization are discussed, and some common misconceptions held by the public as to the role and function of presidential libraries are identified. Criticism and debate from the professional community about…

  2. SU-D-18C-01: A Novel 4D-MRI Technology Based On K-Space Retrospective Sorting

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Liu, Y; Yin, F; Cai, J

    2014-06-01

    Purpose: Current 4D-MRI techniques lack sufficient temporal/spatial resolution and consistent tumor contrast. To overcome these limitations, this study presents the development and initial evaluation of an entirely new framework of 4D-MRI based on k-space retrospective sorting. Methods: An important challenge of the proposed technique is to determine the number of repeated scans(NR) required to obtain sufficient k-space data for 4D-MRI. To do that, simulations using 29 cancer patients' respiratory profiles were performed to derive the relationship between data acquisition completeness(Cp) and NR, also relationship between NR(Cp=95%) and the following factors: total slice(NS), respiratory phase bin length(Lb), frame rate(fr), resolution(R) andmore » image acquisition starting-phase(P0). To evaluate our technique, a computer simulation study on a 4D digital human phantom (XCAT) were conducted with regular breathing (fr=0.5Hz; R=256×256). A 2D echo planer imaging(EPI) MRI sequence were assumed to acquire raw k-space data, with respiratory signal and acquisition time for each k-space data line recorded simultaneously. K-space data was re-sorted based on respiratory phases. To evaluate 4D-MRI image quality, tumor trajectories were measured and compared with the input signal. Mean relative amplitude difference(D) and cross-correlation coefficient(CC) are calculated. Finally, phase-sharing sliding window technique was applied to investigate the feasibility of generating ultra-fast 4D-MRI. Result: Cp increased with NR(Cp=100*[1-exp(-0.19*NR)], when NS=30, Lb=100%/6). NR(Cp=95%) was inversely-proportional to Lb (r=0.97), but independent of other factors. 4D-MRI on XCAT demonstrated highly accurate motion information (D=0.67%, CC=0.996) with much less artifacts than those on image-based sorting 4D-MRI. Ultra-fast 4D-MRI with an apparent temporal resolution of 10 frames/second was reconstructed using the phase-sharing sliding window technique. Conclusions: A novel 4D-MRI

  3. Newsmagazine Visuals and the 1988 Presidential Election.

    ERIC Educational Resources Information Center

    Moriarty, Sandra; Popovich, Mark

    A study examined newsmagazines' visual coverage of the 1988 election to determine if patterns of difference in the visual presentation of candidates existed. A content analysis examined all the visuals (photographs and illustrations) of the presidential and vice-presidential candidates printed in three national weekly newsmagazines--"U.S.…

  4. Efficient Computation of Anharmonic Force Constants via q-space, with Application to Graphene

    NASA Astrophysics Data System (ADS)

    Kornbluth, Mordechai; Marianetti, Chris

    We present a new approach for extracting anharmonic force constants from a sparse sampling of the anharmonic dynamical tensor. We calculate the derivative of the energy with respect to q-space displacements (phonons) and strain, which guarantees the absence of supercell image errors. Central finite differences provide a well-converged quadratic error tail for each derivative, separating the contribution of each anharmonic order. These derivatives populate the anharmonic dynamical tensor in a sparse mesh that bounds the Brillouin Zone, which ensures comprehensive sampling of q-space while exploiting small-cell calculations for efficient, high-throughput computation. This produces a well-converged and precisely-defined dataset, suitable for big-data approaches. We transform this sparsely-sampled anharmonic dynamical tensor to real-space anharmonic force constants that obey full space-group symmetries by construction. Machine-learning techniques identify the range of real-space interactions. We show the entire process executed for graphene, up to and including the fifth-order anharmonic force constants. This method successfully calculates strain-based phonon renormalization in graphene, even under large strains, which solves a major shortcoming of previous potentials.

  5. Space Station

    NASA Technical Reports Server (NTRS)

    Anderton, D. A.

    1985-01-01

    The official start of a bold new space program, essential to maintain the United States' leadership in space was signaled by a Presidential directive to move aggressively again into space by proceeding with the development of a space station. Development concepts for a permanently manned space station are discussed. Reasons for establishing an inhabited space station are given. Cost estimates and timetables are also cited.

  6. PCA-based groupwise image registration for quantitative MRI.

    PubMed

    Huizinga, W; Poot, D H J; Guyader, J-M; Klaassen, R; Coolen, B F; van Kranenburg, M; van Geuns, R J M; Uitterdijk, A; Polfliet, M; Vandemeulebroucke, J; Leemans, A; Niessen, W J; Klein, S

    2016-04-01

    Quantitative magnetic resonance imaging (qMRI) is a technique for estimating quantitative tissue properties, such as the T1 and T2 relaxation times, apparent diffusion coefficient (ADC), and various perfusion measures. This estimation is achieved by acquiring multiple images with different acquisition parameters (or at multiple time points after injection of a contrast agent) and by fitting a qMRI signal model to the image intensities. Image registration is often necessary to compensate for misalignments due to subject motion and/or geometric distortions caused by the acquisition. However, large differences in image appearance make accurate image registration challenging. In this work, we propose a groupwise image registration method for compensating misalignment in qMRI. The groupwise formulation of the method eliminates the requirement of choosing a reference image, thus avoiding a registration bias. The method minimizes a cost function that is based on principal component analysis (PCA), exploiting the fact that intensity changes in qMRI can be described by a low-dimensional signal model, but not requiring knowledge on the specific acquisition model. The method was evaluated on 4D CT data of the lungs, and both real and synthetic images of five different qMRI applications: T1 mapping in a porcine heart, combined T1 and T2 mapping in carotid arteries, ADC mapping in the abdomen, diffusion tensor mapping in the brain, and dynamic contrast-enhanced mapping in the abdomen. Each application is based on a different acquisition model. The method is compared to a mutual information-based pairwise registration method and four other state-of-the-art groupwise registration methods. Registration accuracy is evaluated in terms of the precision of the estimated qMRI parameters, overlap of segmented structures, distance between corresponding landmarks, and smoothness of the deformation. In all qMRI applications the proposed method performed better than or equally well as

  7. 78 FR 42805 - Nixon Presidential Historical Materials: Opening of Materials

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-17

    ... Library in Yorba Linda. The newly released tapes will also be available on August 21, 2013 on the Web at... Nixon Presidential Historical Materials by the Richard Nixon Presidential Library and Museum, a division... required by law, including the PRMPA. DATES: The Richard Nixon Presidential Library and Museum intends to...

  8. The Past and Future of Presidential Primary Debates.

    ERIC Educational Resources Information Center

    Ritter, Kurt; Hellweg, Susan A.

    Studies focusing on televised presidential primary debates include four prespectives. From a historical perspective, televised presidential primary debates have increased slowly from 1956 through 1980. With the 1975 Federal Communications Commission ruling that independently sponsored campaign debates were news events exempt from "equal…

  9. 78 FR 75375 - Advisory Committee on the Presidential Library-Foundation Partnerships

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-11

    ... Presidential Library-Foundation Partnerships AGENCY: National Archives and Records Administration (NARA... Advisory Committee on Presidential Library-Foundation Partnerships. The meeting will be held to discuss NARA's budget and its strategic planning process as it relates to Presidential Libraries. The meeting...

  10. 77 FR 29391 - Advisory Committee on the Presidential Library-Foundation Partnerships

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-17

    ... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Advisory Committee on the Presidential Library... Presidential Library-Foundation Partnerships. The meeting will be held to discuss the National Archives and Records Administration's budget and its strategic planning process as it relates to Presidential Libraries...

  11. Multimodal MRI reveals structural connectivity differences in 22q11 deletion syndrome related to impaired spatial working memory.

    PubMed

    O'Hanlon, Erik; Howley, Sarah; Prasad, Sarah; McGrath, Jane; Leemans, Alexander; McDonald, Colm; Garavan, Hugh; Murphy, Kieran C

    2016-12-01

    Impaired spatial working memory is a core cognitive deficit observed in people with 22q11 Deletion syndrome (22q11DS) and has been suggested as a candidate endophenotype for schizophrenia. However, to date, the neuroanatomical mechanisms describing its structural and functional underpinnings in 22q11DS remain unclear. We quantitatively investigate the cognitive processes and associated neuroanatomy of spatial working memory in people with 22q11DS compared to matched controls. We examine whether there are significant between-group differences in spatial working memory using task related fMRI, Voxel based morphometry and white matter fiber tractography. Multimodal magnetic resonance imaging employing functional, diffusion and volumetric techniques were used to quantitatively assess the cognitive and neuroanatomical features of spatial working memory processes in 22q11DS. Twenty-six participants with genetically confirmed 22q11DS aged between 9 and 52 years and 26 controls aged between 8 and 46 years, matched for age, gender, and handedness were recruited. People with 22q11DS have significant differences in spatial working memory functioning accompanied by a gray matter volume reduction in the right precuneus. Gray matter volume was significantly correlated with task performance scores in these areas. Tractography revealed extensive differences along fibers between task-related cortical activations with pronounced differences localized to interhemispheric commissural fibers within the parietal section of the corpus callosum. Abnormal spatial working memory in 22q11DS is associated with aberrant functional activity in conjunction with gray and white matter structural abnormalities. These anomalies in discrete brain regions may increase susceptibility to the development of psychiatric disorders such as schizophrenia. Hum Brain Mapp 37:4689-4705, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  12. Effects of b-value and number of gradient directions on diffusion MRI measures obtained with Q-ball imaging

    NASA Astrophysics Data System (ADS)

    Schilling, Kurt G.; Nath, Vishwesh; Blaber, Justin; Harrigan, Robert L.; Ding, Zhaohua; Anderson, Adam W.; Landman, Bennett A.

    2017-02-01

    High-angular-resolution diffusion-weighted imaging (HARDI) MRI acquisitions have become common for use with higher order models of diffusion. Despite successes in resolving complex fiber configurations and probing microstructural properties of brain tissue, there is no common consensus on the optimal b-value and number of diffusion directions to use for these HARDI methods. While this question has been addressed by analysis of the diffusion-weighted signal directly, it is unclear how this translates to the information and metrics derived from the HARDI models themselves. Using a high angular resolution data set acquired at a range of b-values, and repeated 11 times on a single subject, we study how the b-value and number of diffusion directions impacts the reproducibility and precision of metrics derived from Q-ball imaging, a popular HARDI technique. We find that Q-ball metrics associated with tissue microstructure and white matter fiber orientation are sensitive to both the number of diffusion directions and the spherical harmonic representation of the Q-ball, and often are biased when under sampled. These results can advise researchers on appropriate acquisition and processing schemes, particularly when it comes to optimizing the number of diffusion directions needed for metrics derived from Q-ball imaging.

  13. "Ruralizing" Presidential Job Advertisements

    ERIC Educational Resources Information Center

    Leist, Jay

    2007-01-01

    Rural community college presidential job advertisements that focus on geography, politics, and culture can improve the likelihood of a good fit between the senior leader and the institution. (Contains 2 figures.)

  14. Presidential Citation for Science and Society

    NASA Astrophysics Data System (ADS)

    2012-07-01

    AGU presented its Presidential Citation for Science and Society to three recipients at a reception on 1 May 2012 in the Rayburn House Office Building as part of the inaugural AGU Science Policy Conference. Google Earth, Jane Lubchenco, who is the under secretary of Commerce for oceans and atmosphere and administrator of the National Oceanic and Atmospheric Administration, and Sen. Olympia Snowe (R-Maine) were recognized for their leadership and vision in shaping policy and heightening public awareness of the value of Earth and space science. “This is an important award because with it AGU brings to light the importance of cutting-edge use-inspired science that helps people, communities, and businesses adapt to climate change and sustainably manage our oceans and coasts,” Lubchenco said.

  15. 78 FR 46402 - Issuance of a Presidential Permit

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-31

    ...: Department of State. ACTION: Notice of Issuance of a Presidential Permit for Vantage Pipeline US LP. SUMMARY: The Department of State issued a Presidential Permit to Vantage Pipeline US LP (``Vantage'') on July 16, 2013, authorizing Vantage to construct, connect, operate, and maintain pipeline facilities at the...

  16. Winnowing the Field: Candidates, Caucuses, and Presidential Elections.

    ERIC Educational Resources Information Center

    Gore, Deborah, Ed.

    1991-01-01

    This issue features articles and activities that concern the history of the presidential election process in the United States, with a special focus on Iowa's role in that process. The following features are included: "Lights, Camera, Action!"; "Presidential Whoopla"; "From Tree Stumps to Living Rooms"; "Wild…

  17. Comparison of multi-fiber reproducibility of PAS-MRI and Q-ball with empirical multiple b-value HARDI

    NASA Astrophysics Data System (ADS)

    Nath, Vishwesh; Schilling, Kurt G.; Blaber, Justin A.; Ding, Zhaohua; Anderson, Adam W.; Landman, Bennett A.

    2017-02-01

    Crossing fibers are prevalent in human brains and a subject of intense interest for neuroscience. Diffusion tensor imaging (DTI) can resolve tissue orientation but is blind to crossing fibers. Many advanced diffusion-weighted magnetic resolution imaging (MRI) approaches have been presented to extract crossing-fibers from high angular resolution diffusion imaging (HARDI), but the relative sensitivity and specificity of approaches remains unclear. Here, we examine two leading approaches (PAS and q-ball) in the context of a large-scale, single subject reproducibility study. A single healthy individual was scanned 11 times with 96 diffusion weighted directions and 10 reference volumes for each of five b-values (1000, 1500, 2000, 2500, 3000 s/mm2) for a total of 5830 volumes (over the course of three sessions). We examined the reproducibility of the number of fibers per voxel, volume fraction, and crossing-fiber angles. For each method, we determined the minimum resolvable angle for each acquisition. Reproducibility of fiber counts per voxel was generally high ( 80% consensus for PAS and 70% for q-ball), but there was substantial bias between individual repetitions and model estimated with all data ( 10% lower consensus for PAS and 15% lower for q-ball). Both PAS and q-ball predominantly discovered fibers crossing at near 90 degrees, but reproducibility was higher for PAS across most measures. Within voxels with low anisotropy, q-ball finds more intra-voxel structure; meanwhile, PAS resolves multiple fibers at greater than 75 degrees for more voxels. These results can inform researchers when deciding between HARDI approaches or interpreting findings across studies.

  18. Improved dynamic MRI reconstruction by exploiting sparsity and rank-deficiency.

    PubMed

    Majumdar, Angshul

    2013-06-01

    In this paper we address the problem of dynamic MRI reconstruction from partially sampled K-space data. Our work is motivated by previous studies in this area that proposed exploiting the spatiotemporal correlation of the dynamic MRI sequence by posing the reconstruction problem as a least squares minimization regularized by sparsity and low-rank penalties. Ideally the sparsity and low-rank penalties should be represented by the l(0)-norm and the rank of a matrix; however both are NP hard penalties. The previous studies used the convex l(1)-norm as a surrogate for the l(0)-norm and the non-convex Schatten-q norm (0<q ≤ 1) as a surrogate for the rank of matrix. Following past research in sparse recovery, we know that non-convex l(p)-norm (0

    MRI sequence by solving a least squares minimization problem regularized by l(p)-norm as the sparsity penalty and Schatten-q norm as the low-rank penalty. There are no efficient algorithms to solve the said problems. In this paper, we derive efficient algorithms to solve them. The experiments have been carried out on Dynamic Contrast Enhanced (DCE) MRI datasets. Both quantitative and qualitative analysis indicates the superiority of our proposed improvement over the existing methods. Copyright © 2013 Elsevier Inc. All rights reserved.

  19. Presidential Teacher Award Winners

    NASA Image and Video Library

    2011-05-19

    NASA Administrator Charles Bolden speaks to recipients of the Presidential Award for Excellence in Mathematics and Science Teaching at NASA Headquarters in Washington on Wednesday, May 19, 2011. Photo Credit: (NASA/Paul E. Alers)

  20. What Not to Do during a Presidential Interview

    ERIC Educational Resources Information Center

    Pulliams, Preston

    2016-01-01

    As a presidential search consultant, Preston Pulliams has had the opportunity to observe and participate in many presidential search interviews and the meetings where hiring decisions are made. He has observed how some interview candidates simply knocked themselves out of contention by employing one or more of five poor interview strategies. In…

  1. Genetics Home Reference: distal 18q deletion syndrome

    MedlinePlus

    ... Veltman JA, van Ravenswaaij-Arts CM. Genotype-phenotype mapping of chromosome 18q deletions by high-resolution array ... L, Pihko H. 18q deletions: clinical, molecular, and brain MRI findings of 14 individuals. Am J Med ...

  2. SU-F-J-158: Respiratory Motion Resolved, Self-Gated 4D-MRI Using Rotating Cartesian K-Space Sampling

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Han, F; Zhou, Z; Yang, Y

    Purpose: Dynamic MRI has been used to quantify respiratory motion of abdominal organs in radiation treatment planning. Many existing 4D-MRI methods based on 2D acquisitions suffer from limited slice resolution and additional stitching artifacts when evaluated in 3D{sup 1}. To address these issues, we developed a 4D-MRI (3D dynamic) technique with true 3D k-space encoding and respiratory motion self-gating. Methods: The 3D k-space was acquired using a Rotating Cartesian K-space (ROCK) pattern, where the Cartesian grid was reordered in a quasi-spiral fashion with each spiral arm rotated using golden angle{sup 2}. Each quasi-spiral arm started with the k-space center-line, whichmore » were used as self-gating{sup 3} signal for respiratory motion estimation. The acquired k-space data was then binned into 8 respiratory phases and the golden angle ensures a near-uniform k-space sampling in each phase. Finally, dynamic 3D images were reconstructed using the ESPIRiT technique{sup 4}. 4D-MRI was performed on 6 healthy volunteers, using the following parameters (bSSFP, Fat-Sat, TE/TR=2ms/4ms, matrix size=500×350×120, resolution=1×1×1.2mm, TA=5min, 8 respiratory phases). Supplemental 2D real-time images were acquired in 9 different planes. Dynamic locations of the diaphragm dome and left kidney were measured from both 4D and 2D images. The same protocol was also performed on a MRI-compatible motion phantom where the motion was programmed with different amplitude (10–30mm) and frequency (3–10/min). Results: High resolution 4D-MRI were obtained successfully in 5 minutes. Quantitative motion measurements from 4D-MRI agree with the ones from 2D CINE (<5% error). The 4D images are free of the stitching artifacts and their near-isotropic resolution facilitates 3D visualization and segmentation of abdominal organs such as the liver, kidney and pancreas. Conclusion: Our preliminary studies demonstrated a novel ROCK 4D-MRI technique with true 3D k-space encoding and

  3. Presidential Signing Statements: Constitutional and Institutional Implications

    DTIC Science & Technology

    2007-04-13

    Association (ABA) recently publishing a report declaring that these instruments are “contrary to the rule of law and our constitutional separation of powers ” when...Force on Presidential Signing Statements and the Separation of Powers Doctrine at p. 5 (August 2006). Presidential Signing Statements: Constitutional...constitutional separation of powers ” when they “claim the authority or state the intention to disregard or decline to enforce all or part of a law...or to

  4. Axon diameter and intra-axonal volume fraction of the corticospinal tract in idiopathic normal pressure hydrocephalus measured by q-space imaging.

    PubMed

    Kamiya, Kouhei; Hori, Masaaki; Miyajima, Masakazu; Nakajima, Madoka; Suzuki, Yuriko; Kamagata, Koji; Suzuki, Michimasa; Arai, Hajime; Ohtomo, Kuni; Aoki, Shigeki

    2014-01-01

    Previous studies suggest that compression and stretching of the corticospinal tract (CST) potentially cause treatable gait disturbance in patients with idiopathic normal pressure hydrocephalus (iNPH). Measurement of axon diameter with diffusion MRI has recently been used to investigate microstructural alterations in neurological diseases. In this study, we investigated alterations in the axon diameter and intra-axonal fraction of the CST in iNPH by q-space imaging (QSI) analysis. Nineteen patients with iNPH and 10 age-matched controls were recruited. QSI data were obtained with a 3-T system by using a single-shot echo planar imaging sequence with the diffusion gradient applied parallel to the antero-posterior axis. By using a two-component low-q fit model, the root mean square displacements of intra-axonal space ( =  axon diameter) and intra-axonal volume fraction of the CST were calculated at the levels of the internal capsule and body of the lateral ventricle, respectively. Wilcoxon's rank-sum test revealed a significant increase in CST intra-axonal volume fraction at the paraventricular level in patients (p<0.001), whereas no significant difference was observed in the axon diameter. At the level of the internal capsule, neither axon diameter nor intra-axonal volume fraction differed significantly between the two groups. Our results suggest that in patients with iNPH, the CST does not undergo irreversible axonal damage but is rather compressed and/or stretched owing to pressure from the enlarged ventricle. These analyses of axon diameter and intra-axonal fraction yield insights into microstructural alterations of the CST in iNPH.

  5. Estimation of the EEG power spectrum using MRI T(2) relaxation time in traumatic brain injury.

    PubMed

    Thatcher, R W; Biver, C; Gomez, J F; North, D; Curtin, R; Walker, R A; Salazar, A

    2001-09-01

    To study the relationship between magnetic resonance imaging (MRI) T(2) relaxation time and the power spectrum of the electroencephalogram (EEG) in long-term follow up of traumatic brain injury. Nineteen channel quantitative electroencephalograms or qEEG, tests of cognitive function and quantitative MRI T(2) relaxation times (qMRI) were measured in 18 mild to severe closed head injured outpatients 2 months to 4.6 years after injury and 11 normal controls. MRI T(2) and the Laplacian of T(2) were then correlated with the power spectrum of the scalp electrical potentials and current source densities of the qEEG. qEEG and qMRI T(2) were related by a frequency tuning with maxima in the alpha (8-12Hz) and the lower EEG frequencies (0.5-5Hz), which varied as a function of spatial location. The Laplacian of T(2) acted like a spatial-temporal "lens" by increasing the spatial-temporal resolution of correlation between 3-dimensional T(2) and the ear referenced alert but resting spontaneous qEEG. The severity of traumatic brain injury can be modeled by a linear transfer function that relates the molecular qMRI to qEEG resonant frequencies.

  6. 76 FR 70765 - Advisory Committee on Presidential Library-Foundation Partnerships

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-15

    ..., 2011 from 9 a.m. to 12 noon. ADDRESSES: The Ronald Reagan Presidential Library and Museum, 40..., College Park, Maryland 20740, telephone number (301) 837-3250. Contact the Presidential Libraries staff at...

  7. Presidential Teacher Award Winners

    NASA Image and Video Library

    2011-05-19

    Recipients of the Presidential Award for Excellence in Mathematics and Science Teaching stand together with NASA Administrator Charles Bolden and chief scientist Waleed Abdalati, center, at NASA Headquarters in Washington on Wednesday, May 19, 2011. Photo Credit: (NASA/Paul E. Alers)

  8. A theoretical signal processing framework for linear diffusion MRI: Implications for parameter estimation and experiment design.

    PubMed

    Varadarajan, Divya; Haldar, Justin P

    2017-11-01

    The data measured in diffusion MRI can be modeled as the Fourier transform of the Ensemble Average Propagator (EAP), a probability distribution that summarizes the molecular diffusion behavior of the spins within each voxel. This Fourier relationship is potentially advantageous because of the extensive theory that has been developed to characterize the sampling requirements, accuracy, and stability of linear Fourier reconstruction methods. However, existing diffusion MRI data sampling and signal estimation methods have largely been developed and tuned without the benefit of such theory, instead relying on approximations, intuition, and extensive empirical evaluation. This paper aims to address this discrepancy by introducing a novel theoretical signal processing framework for diffusion MRI. The new framework can be used to characterize arbitrary linear diffusion estimation methods with arbitrary q-space sampling, and can be used to theoretically evaluate and compare the accuracy, resolution, and noise-resilience of different data acquisition and parameter estimation techniques. The framework is based on the EAP, and makes very limited modeling assumptions. As a result, the approach can even provide new insight into the behavior of model-based linear diffusion estimation methods in contexts where the modeling assumptions are inaccurate. The practical usefulness of the proposed framework is illustrated using both simulated and real diffusion MRI data in applications such as choosing between different parameter estimation methods and choosing between different q-space sampling schemes. Copyright © 2017 Elsevier Inc. All rights reserved.

  9. [Acute myeloid leukemia with monosomy 7 and inv(3)(q21q26.2) complicated with central diabetes insipidus].

    PubMed

    Nanno, Satoru; Hagihara, Kiyoyuki; Sakabe, Manami; Okamura, Hiroshi; Inaba, Akiko; Nagata, Yuki; Nishimoto, Mitsutaka; Koh, Hideo; Nakao, Yoshitaka; Nakane, Takahiko; Nakamae, Hirohisa; Shimono, Taro; Hino, Masayuki

    2013-04-01

    A 20-year-old female presented with thirst, polyposia, and polyuria and was referred to our hospital because of leukocytosis and anemia. Bone marrow aspiration revealed 66.8% myeloperoxidase-positive blasts and trilineage myelodysplasia. The karyotype was 45, XX, inv(3)(q21q26.2), -7[19]. Therefore, a diagnosis of AML with inv(3)(q21q26.2) complicated by -7 was made. Moreover, hyposthenuria and a low anti-diuretic hormone (ADH) level were observed. Although cerebrospinal fluid analysis was normal, magnetic resonance imaging (MRI) revealed the absence of hyperintensity in the neurohypophysis in T1-weighted images. Therefore, she was also diagnosed with diabetes insipidus. After she was administered a desmopressin nasal spray, the volume of urine produced decreased. Following treatment with second induction therapy containing high-dose cytarabine for AML, she achieved complete remission in the bone marrow. Moreover, when the abnormality on MRI and the volume of urine were normalized, she discontinued desmopressin. Although diabetes insipidus is a rare complication of AML, the majority of AML patients who have diabetes insipidus have the abnormal karyotypes with inv(3)(q21q26.2)/t(3;3)(q21;q26.2) and monosomy 7. Further study is required to clarify the pathogenesis and develop a strategy for the treatment of this category of AML.

  10. MRI of the lung gas-space at very low-field using hyperpolarized noble gases

    NASA Technical Reports Server (NTRS)

    Venkatesh, Arvind K.; Zhang, Adelaide X.; Mansour, Joey; Kubatina, Lyubov; Oh, Chang Hyun; Blasche, Gregory; Selim Unlu, M.; Balamore, Dilip; Jolesz, Ferenc A.; Goldberg, Bennett B.; hide

    2003-01-01

    In hyperpolarized (HP) noble-gas magnetic resonance imaging, large nuclear spin polarizations, about 100,000 times that ordinarily obtainable at thermal equilibrium, are created in 3He and 129Xe. The enhanced signal that results can be employed in high-resolution MRI studies of void spaces such as in the lungs. In HP gas MRI the signal-to-noise ratio (SNR) depends only weakly on the static magnetic field (B(0)), making very low-field (VLF) MRI possible; indeed, it is possible to contemplate portable MRI using light-weight solenoids or permanent magnets. This article reports the first in vivo VLF MR images of the lungs in humans and in rats, obtained at a field of only 15 millitesla (150 Gauss).

  11. Killing Forms on the Five-Dimensional Einstein-Sasaki Y(p, q) Spaces

    NASA Astrophysics Data System (ADS)

    Visinescu, Mihai

    2012-12-01

    We present the complete set of Killing-Yano tensors on the five-dimensional Einstein-Sasaki Y(p, q) spaces. Two new Killing-Yano tensors are identified, associated with the complex volume form of the Calabi-Yau metric cone. The corresponding hidden symmetries are not anomalous and the geodesic equations are superintegrable.

  12. 75 FR 47583 - Application to Rescind Presidential Permit; Joint Application for Presidential Permit; British...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-06

    ... facilities authorized by Presidential Permit No. PP-22, as amended, include seven single conductor 132 kilovolt (kV) submarine cables and three single conductor 260 kV DC submarine cables. These cables do not...

  13. Regularized spherical polar fourier diffusion MRI with optimal dictionary learning.

    PubMed

    Cheng, Jian; Jiang, Tianzi; Deriche, Rachid; Shen, Dinggang; Yap, Pew-Thian

    2013-01-01

    Compressed Sensing (CS) takes advantage of signal sparsity or compressibility and allows superb signal reconstruction from relatively few measurements. Based on CS theory, a suitable dictionary for sparse representation of the signal is required. In diffusion MRI (dMRI), CS methods proposed for reconstruction of diffusion-weighted signal and the Ensemble Average Propagator (EAP) utilize two kinds of Dictionary Learning (DL) methods: 1) Discrete Representation DL (DR-DL), and 2) Continuous Representation DL (CR-DL). DR-DL is susceptible to numerical inaccuracy owing to interpolation and regridding errors in a discretized q-space. In this paper, we propose a novel CR-DL approach, called Dictionary Learning - Spherical Polar Fourier Imaging (DL-SPFI) for effective compressed-sensing reconstruction of the q-space diffusion-weighted signal and the EAP. In DL-SPFI, a dictionary that sparsifies the signal is learned from the space of continuous Gaussian diffusion signals. The learned dictionary is then adaptively applied to different voxels using a weighted LASSO framework for robust signal reconstruction. Compared with the start-of-the-art CR-DL and DR-DL methods proposed by Merlet et al. and Bilgic et al., respectively, our work offers the following advantages. First, the learned dictionary is proved to be optimal for Gaussian diffusion signals. Second, to our knowledge, this is the first work to learn a voxel-adaptive dictionary. The importance of the adaptive dictionary in EAP reconstruction will be demonstrated theoretically and empirically. Third, optimization in DL-SPFI is only performed in a small subspace resided by the SPF coefficients, as opposed to the q-space approach utilized by Merlet et al. We experimentally evaluated DL-SPFI with respect to L1-norm regularized SPFI (L1-SPFI), which uses the original SPF basis, and the DR-DL method proposed by Bilgic et al. The experiment results on synthetic and real data indicate that the learned dictionary produces

  14. 75 FR 30863 - Nixon Presidential Historical Materials: Opening of Materials

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-02

    ... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Nixon Presidential Historical Materials: Opening of Materials AGENCY: National Archives and Records Administration. ACTION: Notice of opening of additional materials. SUMMARY: This notice announces the opening of additional Nixon Presidential Historical Materials...

  15. Hypermultiplet gaugings and supersymmetric solutions from 11D and massive IIA supergravity on H^{(p,q)} spaces

    NASA Astrophysics Data System (ADS)

    Guarino, Adolfo

    2018-03-01

    Supersymmetric {AdS}4, {AdS}2 × Σ 2 and asymptotically AdS4 black hole solutions are studied in the context of non-minimal N=2 supergravity models involving three vector multiplets (STU-model) and Abelian gaugings of the universal hypermultiplet moduli space. Such models correspond to consistent subsectors of the {SO}(p,q) and {ISO}(p,q) gauged maximal supergravities that arise from the reduction of 11D and massive IIA supergravity on {H}^{(p,q)} spaces down to four dimensions. A unified description of all the models is provided in terms of a square-root prepotential and the gauging of a duality-hidden symmetry pair of the universal hypermultiplet. Some aspects of M-theory and massive IIA holography are mentioned in passing.

  16. The Presidential Platform on Twenty-First Century Education Goals

    ERIC Educational Resources Information Center

    Tichnor-Wagner, Ariel; Socol, Allison Rose

    2016-01-01

    As social and economic problems change, so do the goals of education reformers. This content analysis of presidential debates transcripts, state of the union addresses, and education budgets from 2000 to 2015 reveals the ways in which presidents and presidential candidates have framed education goals thus far in the twenty-first century. Using…

  17. Design of Multishell Sampling Schemes with Uniform Coverage in Diffusion MRI

    PubMed Central

    Caruyer, Emmanuel; Lenglet, Christophe; Sapiro, Guillermo; Deriche, Rachid

    2017-01-01

    Purpose In diffusion MRI, a technique known as diffusion spectrum imaging reconstructs the propagator with a discrete Fourier transform, from a Cartesian sampling of the diffusion signal. Alternatively, it is possible to directly reconstruct the orientation distribution function in q-ball imaging, providing so-called high angular resolution diffusion imaging. In between these two techniques, acquisitions on several spheres in q-space offer an interesting trade-off between the angular resolution and the radial information gathered in diffusion MRI. A careful design is central in the success of multishell acquisition and reconstruction techniques. Methods The design of acquisition in multishell is still an open and active field of research, however. In this work, we provide a general method to design multishell acquisition with uniform angular coverage. This method is based on a generalization of electrostatic repulsion to multishell. Results We evaluate the impact of our method using simulations, on the angular resolution in one and two bundles of fiber configurations. Compared to more commonly used radial sampling, we show that our method improves the angular resolution, as well as fiber crossing discrimination. Discussion We propose a novel method to design sampling schemes with optimal angular coverage and show the positive impact on angular resolution in diffusion MRI. PMID:23625329

  18. 75 FR 63209 - Advisory Committee on Presidential Library-Foundation Partnerships

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-14

    ... Presidential Libraries staff at [email protected] . SUPPLEMENTARY INFORMATION: The meeting will be open to... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Advisory Committee on Presidential Library-Foundation... Library-Foundation Partnerships. The meeting will be held to discuss the transformation issues at the...

  19. 77 FR 31400 - Nixon Presidential Historical Materials: Opening of Materials

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-25

    ... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Nixon Presidential Historical Materials: Opening of Materials AGENCY: National Archives and Records Administration. ACTION: Notice of Opening of Additional... by the Richard Nixon Presidential Library and Museum, a division of the National Archives and Records...

  20. 77 FR 58179 - Nixon Presidential Historical Materials: Opening of Materials

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-19

    ... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Nixon Presidential Historical Materials: Opening of Materials AGENCY: National Archives and Records Administration ACTION: Notice of opening of additional... by the Richard Nixon Presidential Library and Museum, a division of the National Archives and Records...

  1. 76 FR 27092 - Nixon Presidential Historical Materials: Opening of Materials

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-10

    ... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Nixon Presidential Historical Materials: Opening of Materials AGENCY: National Archives and Records Administration. ACTION: Notice of opening of additional... by the Richard Nixon Presidential Library and Museum, a division of the National Archives and Records...

  2. 75 FR 68384 - Nixon Presidential Historical Materials: Opening of Materials

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-05

    ... NATIONAL ARCHIVES AND RECORDS ADMINISTRATION Nixon Presidential Historical Materials: Opening of Materials AGENCY: National Archives and Records Administration. ACTION: Notice of Opening of Additional... by the Richard Nixon Presidential Library and Museum, a division of the National Archives and Records...

  3. The Presidential Sweepstakes 2000.

    ERIC Educational Resources Information Center

    Doyle, Denis P.

    2000-01-01

    In the 2000 presidential campaigns, both Vice-President Al Gore and Texas Governor George W. Bush want to enlarge the federal role in education. In separate essays, Bush and Gore explain their plans to invest more federal dollars in improving poor children's educational progress and opportunities. (MLH)

  4. Compact Q-balls and Q-shells in a scalar electrodynamics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Arodz, H.; Lis, J.

    2009-02-15

    We investigate spherically symmetric nontopological solitons in electrodynamics with a scalar field self-interaction U{approx}|{psi}| taken from the complex signum-Gordon model. We find Q-balls for small absolute values of the total electric charge Q, and Q-shells when |Q| is large enough. In both cases the charge density exactly vanishes outside certain compact regions in the three-dimensional space. The dependence of the total energy E of small Q-balls on the total electric charge has the form E{approx}|Q|{sup 5/6}, while in the case of very large Q-shells, E{approx}|Q|{sup 7/6}.

  5. Presidential Medal of Freedom

    NASA Image and Video Library

    2012-05-29

    President Barack Obama talks to attendees during the Presidential Medal of Freedom ceremony, held on Tuesday, May 29, 2012, at the White House in Washington. One of the awardees was former United States Marine Corps pilot, astronaut, and United States Senator John Glenn. Photo Credit: (NASA/Bill Ingalls)

  6. Mimicry Is Presidential: Linguistic Style Matching in Presidential Debates and Improved Polling Numbers.

    PubMed

    Romero, Daniel M; Swaab, Roderick I; Uzzi, Brian; Galinsky, Adam D

    2015-10-01

    The current research used the contexts of U.S. presidential debates and negotiations to examine whether matching the linguistic style of an opponent in a two-party exchange affects the reactions of third-party observers. Building off communication accommodation theory (CAT), interaction alignment theory (IAT), and processing fluency, we propose that language style matching (LSM) will improve subsequent third-party evaluations because matching an opponent's linguistic style reflects greater perspective taking and will make one's arguments easier to process. In contrast, research on status inferences predicts that LSM will negatively impact third-party evaluations because LSM implies followership. We conduct two studies to test these competing hypotheses. Study 1 analyzed transcripts of U.S. presidential debates between 1976 and 2012 and found that candidates who matched their opponent's linguistic style increased their standing in the polls. Study 2 demonstrated a causal relationship between LSM and third-party observer evaluations using negotiation transcripts. © 2015 by the Society for Personality and Social Psychology, Inc.

  7. 3 CFR - Presidential Determination on Eligibility of the Federal Republic of Somalia To Receive Defense...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 3 The President 1 2014-01-01 2014-01-01 false Presidential Determination on Eligibility of the Federal Republic of Somalia To Receive Defense Articles and Defense Services Under the Foreign Assistance Act of 1961, as Amended, and the Arms Export Control Act, as Amended Presidential Documents Other Presidential Documents Presidential Determinatio...

  8. 3 CFR - Presidential Determination on the Eligibility of South Sudan To Receive Defense Articles and...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 3 The President 1 2013-01-01 2013-01-01 false Presidential Determination on the Eligibility of South Sudan To Receive Defense Articles and Defense Services Under the Foreign Assistance Act of 1961, as Amended, and the Arms Export Control Act, as Amended Presidential Documents Other Presidential Documents Presidential Determination No. 2012-4 of...

  9. 3 CFR - Designation of Officers of the National Aeronautics And Space Administration To Act as Administrator

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 3 The President 1 2010-01-01 2010-01-01 false Designation of Officers of the National Aeronautics And Space Administration To Act as Administrator Presidential Documents Other Presidential Documents Memorandum of January 16, 2009 Designation of Officers of the National Aeronautics And Space Administration To Act as Administrator Memorandum for...

  10. 76 FR 30942 - Meeting of the Presidential Advisory Council on HIV/AIDS; Correction

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-27

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Meeting of the Presidential Advisory Council on HIV/AIDS... Presidential Advisory Council on HIV/AIDS that will be held on Thursday, May 26, 2011, and Friday, May 27, 2011..., Presidential Advisory Council on HIV/AIDS; Phone: (202) 690-5560. More detailed information about PACHA can be...

  11. Space Cooperation Working Group

    NASA Image and Video Library

    2010-11-18

    NASA Administrator Charles Bolden, left, and NASA Deputy Administrator Lori Garver, welcome Head of the Russian Federal Space Agency Anatoly Perminov, right, for the third Space Cooperation Working Group meeting of the U.S. – Russia Bilateral Presidential Commission on Thursday, Nov. 18, 2010 in Washington. Photo Credit: (NASA/Bill Ingalls)

  12. Q-Space Scattering Power Laws and the Interior Fields of Particles

    DTIC Science & Technology

    2016-02-12

    SECURITY CLASSIFICATION OF: This work studied the relationship between light scattered by particles of any shape and the interior field of that...Release; Distribution Unlimited UU UU UU UU 12-02-2016 7-Jul-2014 6-Apr-2015 Final Report: Q-space Scattering Power Laws and the Interior Fields of...the Army position, policy or decision, unless so designated by other documentation. 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS (ES) U.S

  13. 76 FR 35918 - Nixon Presidential Historical Materials; Opening of Materials

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-20

    ... by the Richard Nixon Presidential Library and Museum, a division of the National Archives and Records... Historical Materials. DATES: The Richard Nixon Presidential Library and Museum intends to make the materials described in this notice available to the public on Wednesday, July 20, 2011, at the Richard Nixon Library...

  14. Presidential Debate Watching, Issue Knowledge, Character Evaluation, and Vote Choice

    ERIC Educational Resources Information Center

    Benoit, William L.; Hansen, Glenn J.

    2004-01-01

    This study employs NES (National Election Survey) data from several presidential elections to investigate the effects of presidential debate watching on voters' issue knowledge, character evaluation, and vote choice. Debates can instill issue knowledge; however, voters are less likely to learn about incumbent presidents seeking re-election after a…

  15. Neustadt's "Presidential Power" and University Governance: A Case Study Analysis.

    ERIC Educational Resources Information Center

    Lander, Byron G.

    The relevance of Richard E. Neustadt's presidential choice making theory to a university presidency is analyzed. This theory, which was introduced in Neustadt's 1960 publication "Presidential Power," is examined in regard to situations that occurred at Kent State University (KSU): the KSU Black United Student (BUS) confrontation with the…

  16. Who Runs Presidential Campaigns?

    ERIC Educational Resources Information Center

    Kindsvatter, Peter S.

    Presidential campaigns in the last decade have provided evidence of the rising influence of the mass media campaign and of campaign consultants. The media, through their power of access to the people, manipulate the public's recognition of a candidate by the amount of coverage given. Newspaper endorsements and the reporting of media-conducted…

  17. 3 CFR - Presidential Determination Pursuant to Section 1245(d)(4)(B) and (C) of the National Defense...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 3 The President 1 2014-01-01 2014-01-01 false Presidential Determination Pursuant to Section 1245(d)(4)(B) and (C) of the National Defense Authorization Act for Fiscal Year 2012 Presidential Documents Other Presidential Documents Presidential Determination No. 2013-10 of June 5, 2013 Presidential Determination Pursuant to Section 1245(d)(4)(B)...

  18. 3 CFR - Presidential Determination Pursuant to Section 1245(d)(4)(B) and (C) of the National Defense...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 3 The President 1 2013-01-01 2013-01-01 false Presidential Determination Pursuant to Section 1245(d)(4)(B) and (C) of the National Defense Authorization Act for Fiscal Year 2012 Presidential Documents Other Presidential Documents Presidential Determination No. 2012-5 of March 30, 2012 Presidential Determination Pursuant to Section 1245(d)(4)(B)...

  19. 3 CFR - Presidential Determination for the Lao People's Democratic Republic Under Section 2(b)(2) of the...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 3 The President 1 2010-01-01 2010-01-01 false Presidential Determination for the Lao People's Democratic Republic Under Section 2(b)(2) of the Export-Import Bank Act of 1945, as amended Presidential Documents Other Presidential Documents Presidential Determination No. 2009-21 of June 12, 2009 Presidential Determination for the Lao People's...

  20. 3 CFR - Presidential Determination Pursuant to Section 1245(d)(4)(B) and (C) of the National Defense...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 3 The President 1 2013-01-01 2013-01-01 false Presidential Determination Pursuant to Section 1245(d)(4)(B) and (C) of the National Defense Authorization Act for Fiscal Year 2012 Presidential Documents Other Presidential Documents Presidential Determination No. 2013-3 of December 7, 2012 Presidential Determination Pursuant to Section 1245(d)(4)(B...

  1. 3 CFR - Presidential Determination Pursuant to Section 1245(d)(4)(B) and (C) of the National Defense...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 3 The President 1 2014-01-01 2014-01-01 false Presidential Determination Pursuant to Section 1245(d)(4)(B) and (C) of the National Defense Authorization Act for Fiscal Year 2012 Presidential Documents Other Presidential Documents Presidential Determination No. 2014-3 of November 29, 2013 Presidential Determination Pursuant to Section 1245(d)(4)(...

  2. 3 CFR - Presidential Determination Pursuant to Section 1245(d)(4)(B) and (C) of the National Defense...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 3 The President 1 2013-01-01 2013-01-01 false Presidential Determination Pursuant to Section 1245(d)(4)(B) and (C) of the National Defense Authorization Act for Fiscal Year 2012 Presidential Documents Other Presidential Documents Presidential Determination No. 2012-9 of June 11, 2012 Presidential Determination Pursuant to Section 1245(d)(4)(B)...

  3. Respiratory motion-resolved, self-gated 4D-MRI using Rotating Cartesian K-space (ROCK): Initial clinical experience on an MRI-guided radiotherapy system.

    PubMed

    Han, Fei; Zhou, Ziwu; Du, Dongsu; Gao, Yu; Rashid, Shams; Cao, Minsong; Shaverdian, Narek; Hegde, John V; Steinberg, Michael; Lee, Percy; Raldow, Ann; Low, Daniel A; Sheng, Ke; Yang, Yingli; Hu, Peng

    2018-06-01

    To optimize and evaluate the respiratory motion-resolved, self-gated 4D-MRI using Rotating Cartesian K-space (ROCK-4D-MRI) method in a 0.35 T MRI-guided radiotherapy (MRgRT) system. The study included seven patients with abdominal tumors treated on the MRgRT system. ROCK-4D-MRI and 2D-CINE, was performed immediately after one of the treatment fractions. Motion quantification based on 4D-MRI was compared with those based on 2D-CINE. The image quality of 4D-MRI was evaluated against 4D-CT. The gross tumor volumes (GTV) were defined based on individual respiratory phases of both 4D-MRI and 4D-CT and compared for their variability over the respiratory cycle. The motion measurements based on 4D-MRI matched well with 2D-CINE, with differences of 1.04 ± 0.52 mm in the superior-inferior and 0.54 ± 0.21 mm in the anterior-posterior directions. The image quality scores of 4D-MRI were significantly higher than 4D-CT, with better tumor contrast (3.29 ± 0.76 vs. 1.86 ± 0.90) and less motion artifacts (3.57 ± 0.53 vs. 2.29 ± 0.95). The GTVs were more consistent in 4D-MRI than in 4D-CT, with significantly smaller GTV variability (9.31 ± 4.58% vs. 34.27 ± 23.33%). Our study demonstrated the clinical feasibility of using the ROCK-4D-MRI to acquire high quality, respiratory motion-resolved 4D-MRI in a low-field MRgRT system. The 4D-MRI image could provide accurate dynamic information for radiotherapy treatment planning. Copyright © 2018 Elsevier B.V. All rights reserved.

  4. 36 CFR 1281.4 - What are the architectural and design standards for Presidential libraries?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... and design standards for Presidential libraries? 1281.4 Section 1281.4 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION NARA FACILITIES PRESIDENTIAL LIBRARY FACILITIES § 1281.4 What are the architectural and design standards for Presidential libraries? The Archivist is...

  5. 36 CFR 1281.4 - What are the architectural and design standards for Presidential libraries?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... and design standards for Presidential libraries? 1281.4 Section 1281.4 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION NARA FACILITIES PRESIDENTIAL LIBRARY FACILITIES § 1281.4 What are the architectural and design standards for Presidential libraries? The Archivist is...

  6. 36 CFR 1281.4 - What are the architectural and design standards for Presidential libraries?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... and design standards for Presidential libraries? 1281.4 Section 1281.4 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION NARA FACILITIES PRESIDENTIAL LIBRARY FACILITIES § 1281.4 What are the architectural and design standards for Presidential libraries? The Archivist is...

  7. 36 CFR 1281.4 - What are the architectural and design standards for Presidential libraries?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... and design standards for Presidential libraries? 1281.4 Section 1281.4 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION NARA FACILITIES PRESIDENTIAL LIBRARY FACILITIES § 1281.4 What are the architectural and design standards for Presidential libraries? The Archivist is...

  8. Light Scattering Analysis of Irregularly Shaped Dust Particles: A Study Using 3-Dimensional Reconstructions from Focused Ion-Beam (FIB) Tomography and Q-Space Analysis

    NASA Astrophysics Data System (ADS)

    Ortiz-Montalvo, D. L.; Conny, J. M.

    2017-12-01

    We study the scattering properties of irregularly shaped ambient dust particles. The way in which they scatter and absorb light has implications for aerosol optical remote sensing and aerosol radiative forcing applications. However, understanding light scattering and absorption by non-spherical particles can be very challenging. We used focused ion-beam scanning electron microscopy and energy-dispersive x-ray spectroscopy (FIB-SEM-EDS) to reconstruct three-dimensional (3-D) configurations of dust particles collected from urban and Asian sources. The 3-D reconstructions were then used in a discrete dipole approximation method (DDA) to determine their scattering properties for a range of shapes, sizes, and refractive indices. Scattering properties where obtained using actual-shapes of the particles, as well as, (theoretical) equivalently-sized geometrical shapes like spheres, ellipsoids, cubes, rectangular prisms, and tetrahedrons. We use Q-space analysis to interpret the angular distribution of the scattered light obtained for each particle. Q-space analysis has been recently used to distinguish scattering by particles of different shapes, and it involves plotting the scattered intensity versus the scattering wave vector (q or qR) on a log-log scale, where q = 2ksin(θ/2), k = 2π/λ, and R = particle effective radius. Results from a limited number of particles show that when Q-space analysis is applied, common patterns appear that agree with previous Q-space studies done on ice crystals and other irregularly shaped particles. More specifically, we found similar Q-space regimes including a forward scattering regime of constant intensity when qR < 1, followed by the Guinier regime when qR ≈ 1, which is then followed by a complex power law regime with a -3 slope regime, a transition regime, and then a -4 slope regime. Currently, Q-space comparisons between actual- and geometric shapes are underway with the objective of determining which geometric shape best

  9. q-deformed superstatistics of the Schrödinger equation in commutative and noncommutative spaces with magnetic field

    NASA Astrophysics Data System (ADS)

    Sargolzaeipor, S.; Hassanabadi, H.; Chung, W. S.

    2018-01-01

    We discuss the q-deformed algebra and study the Schrödinger equation in commutative and noncommutative spaces, under an external magnetic field. In this work, we obtain the energy spectrum by an analytical method and the thermodynamic properties of the system by using the q-deformed superstatistics are calculated. Actually, we derive a generalized version of the ordinary superstatistic for the non-equilibrium systems. Also, different effective Boltzmann factor descriptions are derived. In addition, we discuss about the results for various values of θ in commutative and noncommutative spaces and, to illustrate the results, some figures are plotted.

  10. 2007 NCTE Presidential Address: Where Ignorant Armies Clash by Night

    ERIC Educational Resources Information Center

    Yatvin, Joanne

    2008-01-01

    This article presents the text of Joanne Yatvin's presidential address, delivered at the NCTE Annual Convention in New York City in November 2007. The title of her presidential address, "Where Ignorant Armies Clash by Night," was taken from Matthew Arnold's (1867) poem "Dover Beach." Yatvin states that the federal government…

  11. 3 CFR - Presidential Determination on a U.S. Export-Import Bank Transaction With Vietnam

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Bank Transaction With Vietnam Presidential Documents Other Presidential Documents Presidential... With Vietnam Memorandum for the Secretary of State Pursuant to section 2(b)(2)(D) of the Export-Import...,890 to the Vietnam Post and Telecommunications Group, a wholly state-owned company, for the purchase...

  12. Presidential Medal of Freedom ceremony on This Week @NASA – November 27, 2015

    NASA Image and Video Library

    2015-11-27

    During a Nov. 24 ceremony at the White House, former NASA mathematician and physicist Katherine Johnson was one of seventeen individuals to receive the Presidential Medal of Freedom from President Obama. It is the nation’s highest civilian honor – given for meritorious contributions to the security or national interests of the United States, to world peace, or to cultural or other significant public or private endeavors. Johnson's work influenced NASA space programs – from Project Mercury through the space shuttle. Her calculations were used for some of NASA’s most historic missions – including the 1961 flight of Alan Shepard, the first American in space; the 1962 flight during which John Glenn became the first American to orbit Earth; and the 1969 Apollo 11 mission to the moon. Also, Happy Thanksgiving, from space, Next space station crew prepares for launch, Anniversary of first 3-D part printed in space, First flight mirror installed on Webb telescope, Climate and marine study and more!

  13. 36 CFR 1281.14 - What type of endowment is required for a Presidential library?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... required for a Presidential library? 1281.14 Section 1281.14 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION NARA FACILITIES PRESIDENTIAL LIBRARY FACILITIES § 1281.14 What type of endowment is required for a Presidential library? (a) Endowment requirement—new libraries. The foundation or...

  14. 36 CFR 1281.14 - What type of endowment is required for a Presidential library?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... required for a Presidential library? 1281.14 Section 1281.14 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION NARA FACILITIES PRESIDENTIAL LIBRARY FACILITIES § 1281.14 What type of endowment is required for a Presidential library? (a) Endowment requirement—new libraries. The foundation or...

  15. 36 CFR 1281.14 - What type of endowment is required for a Presidential library?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... required for a Presidential library? 1281.14 Section 1281.14 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION NARA FACILITIES PRESIDENTIAL LIBRARY FACILITIES § 1281.14 What type of endowment is required for a Presidential library? (a) Endowment requirement—new libraries. The foundation or...

  16. 36 CFR 1281.14 - What type of endowment is required for a Presidential library?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... required for a Presidential library? 1281.14 Section 1281.14 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION NARA FACILITIES PRESIDENTIAL LIBRARY FACILITIES § 1281.14 What type of endowment is required for a Presidential library? (a) Endowment requirement—new libraries. The foundation or...

  17. Space Exploration Initiative: Chronology

    NASA Technical Reports Server (NTRS)

    McCurdy, Howard E.

    1992-01-01

    This chronology gives an overview of the human space exploration initiative from 1956 through 1989. Details are given for the political milestones of the initiative, including information on presidential mandates and NASA Administrator appointments.

  18. Presidential Medal of Freedom

    NASA Image and Video Library

    2012-05-29

    Major S. Lee Meyer, USMC, Military Aide to the President, holds the Presidential Medal of Freedom that is to be presented by President Barack Obama to former United States Marine Corps pilot, astronaut, and United States Senator John Glenn, Tuesday, May 29, 2012, during a ceremony at the White House in Washington. Photo Credit: (NASA/Bill Ingalls)

  19. 36 CFR 1280.92 - When are the Presidential library museums open to the public?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... library museums open to the public? 1280.92 Section 1280.92 Parks, Forests, and Public Property NATIONAL... Use of Facilities in Presidential Libraries? § 1280.92 When are the Presidential library museums open to the public? (a) The hours of operation at Presidential Library museums vary. Please contact the...

  20. 36 CFR 1280.92 - When are the Presidential library museums open to the public?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... library museums open to the public? 1280.92 Section 1280.92 Parks, Forests, and Public Property NATIONAL... Use of Facilities in Presidential Libraries? § 1280.92 When are the Presidential library museums open to the public? (a) The Presidential library museums are open every day except Thanksgiving, December...

  1. 36 CFR 1280.92 - When are the Presidential library museums open to the public?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... library museums open to the public? 1280.92 Section 1280.92 Parks, Forests, and Public Property NATIONAL... Use of Facilities in Presidential Libraries? § 1280.92 When are the Presidential library museums open to the public? (a) The Presidential library museums are open every day except Thanksgiving, December...

  2. 36 CFR 1280.92 - When are the Presidential library museums open to the public?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... library museums open to the public? 1280.92 Section 1280.92 Parks, Forests, and Public Property NATIONAL... Use of Facilities in Presidential Libraries? § 1280.92 When are the Presidential library museums open to the public? (a) The Presidential library museums are open every day except Thanksgiving, December...

  3. Presidential Search: Selecting the Top Candidates.

    ERIC Educational Resources Information Center

    Stead, Ronald S.

    1988-01-01

    The winnowing of a large number of presidential candidates to a smaller, more manageable group is discussed. Initial screening, candidate information, evaluation form, reference checking, and selecting interviewees are described. (MLW)

  4. A brain MRI bias field correction method created in the Gaussian multi-scale space

    NASA Astrophysics Data System (ADS)

    Chen, Mingsheng; Qin, Mingxin

    2017-07-01

    A pre-processing step is needed to correct for the bias field signal before submitting corrupted MR images to such image-processing algorithms. This study presents a new bias field correction method. The method creates a Gaussian multi-scale space by the convolution of the inhomogeneous MR image with a two-dimensional Gaussian function. In the multi-Gaussian space, the method retrieves the image details from the differentiation of the original image and convolution image. Then, it obtains an image whose inhomogeneity is eliminated by the weighted sum of image details in each layer in the space. Next, the bias field-corrected MR image is retrieved after the Υ correction, which enhances the contrast and brightness of the inhomogeneity-eliminated MR image. We have tested the approach on T1 MRI and T2 MRI with varying bias field levels and have achieved satisfactory results. Comparison experiments with popular software have demonstrated superior performance of the proposed method in terms of quantitative indices, especially an improvement in subsequent image segmentation.

  5. 3 CFR - Presidential Determination for the Kingdom of Cambodia Under Section 2(b)(2) of the Export-Import...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 3 The President 1 2010-01-01 2010-01-01 false Presidential Determination for the Kingdom of Cambodia Under Section 2(b)(2) of the Export-Import Bank Act of 1945, as amended Presidential Documents Other Presidential Documents Presidential Determination No. 2009-20 of June 12, 2009 Presidential Determination for the Kingdom of Cambodia Under...

  6. Q-space analysis of light scattering by ice crystals

    NASA Astrophysics Data System (ADS)

    Heinson, Yuli W.; Maughan, Justin B.; Ding, Jiachen; Chakrabarti, Amitabha; Yang, Ping; Sorensen, Christopher M.

    2016-12-01

    Q-space analysis is applied to extensive simulations of the single-scattering properties of ice crystals with various habits/shapes over a range of sizes. The analysis uncovers features common to all the shapes: a forward scattering regime with intensity quantitatively related to the Rayleigh scattering by the particle and the internal coupling parameter, followed by a Guinier regime dependent upon the particle size, a complex power law regime with incipient two dimensional diffraction effects, and, in some cases, an enhanced backscattering regime. The effects of significant absorption on the scattering profile are also studied. The overall features found for the ice crystals are similar to features in scattering from same sized spheres.

  7. The Presidential Innovation Award for Environmental ...

    EPA Pesticide Factsheets

    The Presidential Innovation Award for Environmental Educators recognizes outstanding kindergarten through grade 12 teachers who employ innovative approaches to environmental education and use the environment as a context for learning for their students.

  8. Stability of iterative procedures with errors for approximating common fixed points of a couple of q-contractive-like mappings in Banach spaces

    NASA Astrophysics Data System (ADS)

    Zeng, Lu-Chuan; Yao, Jen-Chih

    2006-09-01

    Recently, Agarwal, Cho, Li and Huang [R.P. Agarwal, Y.J. Cho, J. Li, N.J. Huang, Stability of iterative procedures with errors approximating common fixed points for a couple of quasi-contractive mappings in q-uniformly smooth Banach spaces, J. Math. Anal. Appl. 272 (2002) 435-447] introduced the new iterative procedures with errors for approximating the common fixed point of a couple of quasi-contractive mappings and showed the stability of these iterative procedures with errors in Banach spaces. In this paper, we introduce a new concept of a couple of q-contractive-like mappings (q>1) in a Banach space and apply these iterative procedures with errors for approximating the common fixed point of the couple of q-contractive-like mappings. The results established in this paper improve, extend and unify the corresponding ones of Agarwal, Cho, Li and Huang [R.P. Agarwal, Y.J. Cho, J. Li, N.J. Huang, Stability of iterative procedures with errors approximating common fixed points for a couple of quasi-contractive mappings in q-uniformly smooth Banach spaces, J. Math. Anal. Appl. 272 (2002) 435-447], Chidume [C.E. Chidume, Approximation of fixed points of quasi-contractive mappings in Lp spaces, Indian J. Pure Appl. Math. 22 (1991) 273-386], Chidume and Osilike [C.E. Chidume, M.O. Osilike, Fixed points iterations for quasi-contractive maps in uniformly smooth Banach spaces, Bull. Korean Math. Soc. 30 (1993) 201-212], Liu [Q.H. Liu, On Naimpally and Singh's open questions, J. Math. Anal. Appl. 124 (1987) 157-164; Q.H. Liu, A convergence theorem of the sequence of Ishikawa iterates for quasi-contractive mappings, J. Math. Anal. Appl. 146 (1990) 301-305], Osilike [M.O. Osilike, A stable iteration procedure for quasi-contractive maps, Indian J. Pure Appl. Math. 27 (1996) 25-34; M.O. Osilike, Stability of the Ishikawa iteration method for quasi-contractive maps, Indian J. Pure Appl. Math. 28 (1997) 1251-1265] and many others in the literature.

  9. NREL Employee Appointed to Presidential Panel

    Science.gov Websites

    Employee Appointed to Presidential Panel For more information contact: e:mail: Public Affairs Development Panel. The panel will review current and projected U.S. energy research and development programs

  10. 2008 Preserve America Presidential Awards

    Science.gov Websites

    Project, New York, New York; Corinth and Alcorn County Mississippi Heritage Tourism Initiative; Lower East and Alcorn County Mississippi Heritage Tourism Initiative were Rosemary Williams, Chairperson, Siege Heritage Tourism Initiative Mrs. Laura Bush poses for a photo with Preserve America Presidential Award

  11. Presidential Primaries: Front-Loaded Fiascoes?

    ERIC Educational Resources Information Center

    Gans, Curtis

    1996-01-01

    Criticizes the presidential primary process as possibly leading to the destruction of the two-party system. Claims that the current process limits the competition to the rich and famous, enhances the worst aspects of campaigning, and evaluates candidates purely on their political skills. Briefly discusses some reform proposals. (MJP)

  12. 36 CFR § 1281.4 - What are the architectural and design standards for Presidential libraries?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... design standards for Presidential libraries? § 1281.4 Section § 1281.4 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION NARA FACILITIES PRESIDENTIAL LIBRARY FACILITIES § 1281.4 What are the architectural and design standards for Presidential libraries? The Archivist is...

  13. A Visual Analysis of the 1980 Houston Republican Presidential Primary Debate.

    ERIC Educational Resources Information Center

    Hellweg, Susan A.; Phillips, Steven L.

    In partial replication of an analysis of the 1976 presidential campaign debates, two researchers analyzed the debate between Republican presidential candidates Ronald Reagan and George Bush (Houston, April 23, 1980) for its visual features, (amount and type of camera shots). The visual categories by which camera shots were coded included…

  14. Presidential Green Chemistry Challenge: 2009 Academic Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2009 award winner, Professor Krzysztof Matyjaszewski, developed Atom Transfer Radical Polymerization to make polymers with copper catalysts and environmentally friendly reducing agents.

  15. 3 CFR - Presidential Determination on the Delegation of Certifications Under Section 1512 of Public Law...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 3 The President 1 2010-01-01 2010-01-01 false Presidential Determination on the Delegation of Certifications Under Section 1512 of Public Law 105-261 Presidential Documents Other Presidential Documents..., including section 301 of Title 3, United States Code, I hereby delegate to you the functions of the...

  16. 36 CFR § 1281.14 - What type of endowment is required for a Presidential library?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... required for a Presidential library? § 1281.14 Section § 1281.14 Parks, Forests, and Public Property NATIONAL ARCHIVES AND RECORDS ADMINISTRATION NARA FACILITIES PRESIDENTIAL LIBRARY FACILITIES § 1281.14 What type of endowment is required for a Presidential library? (a) Endowment requirement—new libraries. The...

  17. Presidential Green Chemistry Challenge: 2007 Academic Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2007 award winner, Professor Michael J. Krische, developed selective C-C bond-forming hydrogenation without organometallic reagents, eliminating hazardous reagents and hazardous waste.

  18. Presidential Survival in Tough Times.

    ERIC Educational Resources Information Center

    Bowen, Raymond C.

    Surviving the position of college president requires the development of a presidential survival kit filled with idiosyncratic items not normally associated with formal educational training. Strength, agility, control, and the ability to improvise are some of the talents required of a college president. In addition, the longevity and success of a…

  19. 36 CFR 1280.90 - What are the rules of conduct while visiting the Presidential libraries?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... while visiting the Presidential libraries? 1280.90 Section 1280.90 Parks, Forests, and Public Property... Apply for Use of Facilities in Presidential Libraries? § 1280.90 What are the rules of conduct while visiting the Presidential libraries? In addition to the rules in Subpart A, when visiting the museums of...

  20. 36 CFR 1280.90 - What are the rules of conduct while visiting the Presidential libraries?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... while visiting the Presidential libraries? 1280.90 Section 1280.90 Parks, Forests, and Public Property... Apply for Use of Facilities in Presidential Libraries? § 1280.90 What are the rules of conduct while visiting the Presidential libraries? In addition to the rules in Subpart A, when visiting the museums of...

  1. 36 CFR 1280.90 - What are the rules of conduct while visiting the Presidential libraries?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... while visiting the Presidential libraries? 1280.90 Section 1280.90 Parks, Forests, and Public Property... Apply for Use of Facilities in Presidential Libraries? § 1280.90 What are the rules of conduct while visiting the Presidential libraries? In addition to the rules in Subpart A, when visiting the museums of...

  2. 36 CFR 1280.90 - What are the rules of conduct while visiting the Presidential libraries?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... while visiting the Presidential libraries? 1280.90 Section 1280.90 Parks, Forests, and Public Property... Apply for Use of Facilities in Presidential Libraries? § 1280.90 What are the rules of conduct while visiting the Presidential libraries? In addition to the rules in Subpart A, when visiting the museums of...

  3. 3 CFR - Presidential Determination Under Section 402 (c)(2)(A) of the Trade Act of 1974-Republic of Belarus

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 3 The President 1 2010-01-01 2010-01-01 false Presidential Determination Under Section 402 (c)(2)(A) of the Trade Act of 1974-Republic of Belarus Presidential Documents Other Presidential Documents Presidential Determination No. 2009-22 of July 1, 2009 Presidential Determination Under Section 402 (c)(2)(A) of the Trade Act of 1974—Republic of...

  4. Presidential Green Chemistry Challenge: 2003 Academic Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2003 award winner, Professor Richard A. Gross, developed a transesterification to make polyol-containing polyesters using lipase, replacing heavy metal catalysts and hazardous solvents.

  5. On Becoming Themselves: The 1964-1968 Presidential Scholars 40 Years Later

    ERIC Educational Resources Information Center

    Kaufmann, Felice A.; Matthews, Dona J.

    2012-01-01

    Every year since 1964, approximately 120 high-school seniors have been selected for presidential recognition, from across the United States. As the first cohort of Presidential Scholars enters their 60s, we wanted to hear what they think about the roles that academic, professional, and personal achievement have played in their lives and to…

  6. Inaccuracies in Media Coverage of the 1996 and 2000 Presidential Debates.

    ERIC Educational Resources Information Center

    Benoit, William L.; Currie, Heather

    2001-01-01

    Compares data from a content analysis of the 1996 and 2000 presidential debates with news coverage of those debates. Concludes that the average newspaper story in 2000 only reported 7% of what the candidates said in a debate. Suggests that voters cannot expect to obtain an accurate or complete representation of presidential debates from media…

  7. 36 CFR § 1280.92 - When are the Presidential library museums open to the public?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... library museums open to the public? § 1280.92 Section § 1280.92 Parks, Forests, and Public Property... Apply for Use of Facilities in Presidential Libraries? § 1280.92 When are the Presidential library museums open to the public? (a) The Presidential library museums are open every day except Thanksgiving...

  8. Presidential and bureaucratic policy-making: The case of Mexican oil policy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    de la Luz Valverde Rocha, M.

    1991-01-01

    A close examination of the literature yielded two different, but vague models of Mexican policy-making: (1) closed presidential policy-making and (2) open presidential policy-making. These two models are tested by identifying the regime's policy-making structures and by explaining the manner in which they operated to produce oil policy in two presidential administrations. To attain these goals, the oil policy-making process was divided into several stages. The policy roles played by different actors in the various stages of policy-making were analyzed. The process they engaged in to produce oil policy was also examined. The findings lend strong support to the openmore » presidential policy-making model. The most salient features of this model are: (1) the president and different members of the Mexican federal bureaucracy share policy-making functions, power, and influence; (2) policymakers engage in a political process of persuasion, coalition building, information functions, power, and influence; and (3) policymakers engage in these and other political techniques to produce government decisions and actions.« less

  9. [Imaging and quantitative measurement of brain extracellular space using MRI Gd-DTPA tracer method].

    PubMed

    He, Qing-yuan; Han, Hong-bin; Xu, Fang-jing-wei; Yan, Jun-hao; Zeng, Jin-jin; Li, Xiao-gang; Fu, Yu; Peng, Yun; Chen, He; Hou, Chao; Xu, Xiao-juan

    2010-04-18

    To observe the diffusion of Gd-DTPA in brain extracellular space (ECS) by magnetic resonance imaging(MRI) and investigate the feasibility of ECS measurement by using MRI tracer method in vivo. 2 microL Gd-DTPA was introduced into ECS by caudate nucleus according to stereotaxic atlas in 8 Sprague Dawley(SD) rats (male, 280-320 g). The MRI scans were performed at 1 h, 3 h, 6 h, 9 h and 12 h respectively after administration. MRI appearances of Gd-DTPA diffusion and distribution was observed and compared. The MRI signal enhancement was measured at each time point. The neuroethology assessment was performed after MRI scanning at 12 h. The injection was accurate at the center of the caudate nucleus in 6 rats, while, at the capsula externa in other 2 rats. Gd-DTPA diffused isotropically after it was introduced into caudate nucleus, which spread into lateral cortex at 3 h. The MRI signal enhancement distributed mainly in the middle cerebral artery territory. A significant difference was found between the signal enhancement ratio at 1 h and that at 3 h in the original point of caudate nucleus (t=95.63, P<0.01), and the signal enhancement attenuated following the exponential power function y=1.7886x(-0.1776) (R2=0.94). In 2 rats with the injection point at capsula externa, Gd-DTPA diffused anisotropically along the fiber track of white matter during 1 h to 3 h, and spread into the lateral cortex at 6 h. The diffusion and clearance of Gd-DTPA in brain ECS could be monitored and measured quantitatively in vivo by MRI tracer method.

  10. Presidential Green Chemistry Challenge: 1997 Academic Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 1997 award winner, Professor Joseph M. DeSimone, developed surfactants that allow carbon dioxide to be a solvent for chemical manufacturing, replacing hazardous chemical solvents.

  11. Presidential Green Chemistry Challenge: 1996 Academic Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 1996 award winner, Professor Mark Holtzapple, developed methods to convert waste biomass (e.g., sewage sludge, agricultural wastes), into animal feed, industrial chemicals, or fuels.

  12. Seven Democratic Presidential Candidates Debate Educational Issues.

    ERIC Educational Resources Information Center

    Equity and Excellence, 1988

    1988-01-01

    Provides the transcript of a debate on educational issues among Democratic presidential candidates Paul Simon, Albert Gore, Joseph Biden, Jesse Jackson, Bruce Babbitt, Richard Gephart, and Michael Dukakis. (BJV)

  13. Defining the Issues of a Presidential Election from Televised Political Spot Advertisements.

    ERIC Educational Resources Information Center

    Shyles, Leonard C.

    1983-01-01

    Discerns issues of the 1980 presidential primary campaigns through content analysis of issues presented in televised political spot advertisements created for nine presidential primary candidates. Results indicate Democrats were most concerned with the economy, energy, foreign policy, and national security, while Republicans focused on federalism…

  14. 78 FR 19710 - Meeting of the Presidential Advisory Council on HIV/AIDS

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-02

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Meeting of the Presidential Advisory Council on HIV/AIDS... on HIV/AIDS (PACHA) will hold a meeting to discuss implementation of the Patient Protection and... CONTACT: Ms. Caroline Talev, Public Health Assistant, Presidential Advisory Council on HIV/AIDS...

  15. Presidential Green Chemistry Challenge: 2000 Academic Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2000 award winner, Professor Chi-Huey Wong, developed reactions with enzymes and safer solvents that can replace traditional reactions done with toxic metals and hazardous solvents.

  16. Presidential Green Chemistry Challenge: 2006 Academic Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2006 award winner, Professor Galen J. Suppes, developed a process to convert waste glycerin from biodiesel production into propylene glycol to replace ethylene glycol in antifreeze.

  17. [Heath and political regimes: presidential or parliamentary government for Colombia?].

    PubMed

    Idrovo, Alvaro J

    2007-01-01

    Changing the presidential regime for a parliamentarian one is currently be-ing discussed in Colombia. This preliminary study explores the potential effects on health of both presidential and parliamentary regimes by using world-wide data. An ecological study was undertaken using countries from which comparable information concerning life-expectancy at birth, political regime, economic development, inequality in income, social capital (as measured by general-ised trust or Corruption Perceptions Index), political rights, civil freedom and cultural diversity could be obtained. Life-expectancy at birth and macro-determinants were compared between both political regimes. The co-relationship between these macro-determinants was estimated and the relationship between political regimen and life-expectancy at birth was estimated using robust regression. Crude analysis revealed that parliamentary countries have greater life-expectancy at birth than countries having a presidential regime. Significant co-relationships between all macro-determinants were observed. No differential effects were observed between both political regimes regarding life-expectancy at birth in multiple robust regressions. There is no evidence that presidential or parliamentary regimes provide greater levels of health for the population. It is suggested that public health policies be focused on other macro-determinants having more known effects on health, such as income inequality.

  18. 77 FR 59196 - Meeting of the Presidential Advisory Council on HIV/AIDS

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-26

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Meeting of the Presidential Advisory Council on HIV/AIDS... on HIV/AIDS (PACHA) will hold a meeting. The meeting will be open to the public. DATES: The meeting... CONTACT: Ms. Caroline Talev, Public Health Assistant, Presidential Advisory Council on HIV/AIDS...

  19. 75 FR 2546 - Meeting of the Presidential Advisory Council on HIV/AIDS

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-15

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Meeting of the Presidential Advisory Council on HIV/AIDS... HIV/AIDS (PACHA) will hold a meeting. The meeting will be open to the public. DATES: The meeting will... FURTHER INFORMATION CONTACT: Mr. Melvin Joppy, Committee Manager, Presidential Advisory Council on HIV...

  20. Singular dynamics of a q-difference Painlevé equation in its initial-value space

    NASA Astrophysics Data System (ADS)

    Joshi, N.; Lobb, S. B.

    2016-01-01

    We construct the initial-value space of a q-discrete first Painlevé equation explicitly and describe the behaviours of its solutions w(n) in this space as n\\to ∞ , with particular attention paid to neighbourhoods of exceptional lines and irreducible components of the anti-canonical divisor. These results show that trajectories starting in domains bounded away from the origin in initial value space are repelled away from such singular lines. However, the dynamical behaviours in neighbourhoods containing the origin are complicated by the merger of two simple base points at the origin in the limit. We show that these lead to a saddle-point-type behaviour in a punctured neighbourhood of the origin.

  1. Presidential Green Chemistry Challenge: 2005 Academic Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2005 award winner, Professor Robin D. Rogers, used ionic liquids to dissolve and process cellulose from wood, cloth, or paper to make new biorenewable or biocompatible materials.

  2. Presidential Green Chemistry Challenge: 1999 Academic Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 1999 award winner, Professor Terry Collins, developed a series of TAML oxidant activators that work with hydrogen peroxide to replace chlorine bleaches for paper making and laundry.

  3. Presidential Green Chemistry Challenge: 2011 Academic Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2011 award winner, Professor Bruce H. Lipshutz, designed a novel, second-generation surfactant called TPGS-750-M. It is a designer surfactant composed of safe, inexpensive ingredients.

  4. 44 CFR 206.38 - Presidential determination.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Presidential determination. 206.38 Section 206.38 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE FEDERAL DISASTER ASSISTANCE The Declaration Process § 206...

  5. 44 CFR 206.38 - Presidential determination.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 44 Emergency Management and Assistance 1 2013-10-01 2013-10-01 false Presidential determination. 206.38 Section 206.38 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE FEDERAL DISASTER ASSISTANCE The Declaration Process § 206...

  6. 44 CFR 206.38 - Presidential determination.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 44 Emergency Management and Assistance 1 2012-10-01 2011-10-01 true Presidential determination. 206.38 Section 206.38 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE FEDERAL DISASTER ASSISTANCE The Declaration Process § 206...

  7. 44 CFR 206.38 - Presidential determination.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 44 Emergency Management and Assistance 1 2011-10-01 2011-10-01 false Presidential determination. 206.38 Section 206.38 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE FEDERAL DISASTER ASSISTANCE The Declaration Process § 206...

  8. 44 CFR 206.38 - Presidential determination.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 44 Emergency Management and Assistance 1 2014-10-01 2014-10-01 false Presidential determination. 206.38 Section 206.38 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY DISASTER ASSISTANCE FEDERAL DISASTER ASSISTANCE The Declaration Process § 206...

  9. 77 FR 74017 - Meeting of the Presidential Advisory Council on HIV/AIDS

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-12

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Meeting of the Presidential Advisory Council on HIV/AIDS... on HIV/AIDS (PACHA) will hold a conference call. The call will be open to the public. DATES: The call...: Ms. Caroline Talev, Public Health Assistant, Presidential Advisory Council on HIV/AIDS, Department of...

  10. 75 FR 19403 - Meeting of the Presidential Advisory Council on HIV/AIDS

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-14

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Meeting of the Presidential Advisory Council on HIV/AIDS... HIV/AIDS (PACHA) will hold a meeting. The meeting will be open to the public. DATES: The meeting will..., Committee Manager, Presidential Advisory Council on HIV/AIDS, Department of Health and Human Services, 200...

  11. 76 FR 1167 - Meeting of the Presidential Advisory Council on HIV/AIDS

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-07

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Meeting of the Presidential Advisory Council on HIV/AIDS... on HIV/AIDS (PACHA) will hold a meeting. The meeting will be open to the public. DATES: The meeting... Manager, Presidential Advisory Council on HIV/AIDS, Department of Health and Human Services, 200...

  12. Presidential Green Chemistry Challenge: 2004 Academic Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2004 award winners, Professors Charles A. Eckert and Charles L. Liotta, use supercritical CO2 as a solvent to combine reactions and separations, improve efficiency, and reduce waste.

  13. Presidential Green Chemistry Challenge: 2008 Academic Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2008 award winners, Professors Robert E. Maleczka, Jr. and Milton R. Smith, III, developed halogen-free, catalytic C-H activation/borylation to make aryl and heteroaryl boronic esters.

  14. State-space model with deep learning for functional dynamics estimation in resting-state fMRI.

    PubMed

    Suk, Heung-Il; Wee, Chong-Yaw; Lee, Seong-Whan; Shen, Dinggang

    2016-04-01

    Studies on resting-state functional Magnetic Resonance Imaging (rs-fMRI) have shown that different brain regions still actively interact with each other while a subject is at rest, and such functional interaction is not stationary but changes over time. In terms of a large-scale brain network, in this paper, we focus on time-varying patterns of functional networks, i.e., functional dynamics, inherent in rs-fMRI, which is one of the emerging issues along with the network modelling. Specifically, we propose a novel methodological architecture that combines deep learning and state-space modelling, and apply it to rs-fMRI based Mild Cognitive Impairment (MCI) diagnosis. We first devise a Deep Auto-Encoder (DAE) to discover hierarchical non-linear functional relations among regions, by which we transform the regional features into an embedding space, whose bases are complex functional networks. Given the embedded functional features, we then use a Hidden Markov Model (HMM) to estimate dynamic characteristics of functional networks inherent in rs-fMRI via internal states, which are unobservable but can be inferred from observations statistically. By building a generative model with an HMM, we estimate the likelihood of the input features of rs-fMRI as belonging to the corresponding status, i.e., MCI or normal healthy control, based on which we identify the clinical label of a testing subject. In order to validate the effectiveness of the proposed method, we performed experiments on two different datasets and compared with state-of-the-art methods in the literature. We also analyzed the functional networks learned by DAE, estimated the functional connectivities by decoding hidden states in HMM, and investigated the estimated functional connectivities by means of a graph-theoretic approach. Copyright © 2016 Elsevier Inc. All rights reserved.

  15. State-space model with deep learning for functional dynamics estimation in resting-state fMRI

    PubMed Central

    Suk, Heung-Il; Wee, Chong-Yaw; Lee, Seong-Whan; Shen, Dinggang

    2017-01-01

    Studies on resting-state functional Magnetic Resonance Imaging (rs-fMRI) have shown that different brain regions still actively interact with each other while a subject is at rest, and such functional interaction is not stationary but changes over time. In terms of a large-scale brain network, in this paper, we focus on time-varying patterns of functional networks, i.e., functional dynamics, inherent in rs-fMRI, which is one of the emerging issues along with the network modelling. Specifically, we propose a novel methodological architecture that combines deep learning and state-space modelling, and apply it to rs-fMRI based Mild Cognitive Impairment (MCI) diagnosis. We first devise a Deep Auto-Encoder (DAE) to discover hierarchical non-linear functional relations among regions, by which we transform the regional features into an embedding space, whose bases are complex functional networks. Given the embedded functional features, we then use a Hidden Markov Model (HMM) to estimate dynamic characteristics of functional networks inherent in rs-fMRI via internal states, which are unobservable but can be inferred from observations statistically. By building a generative model with an HMM, we estimate the likelihood of the input features of rs-fMRI as belonging to the corresponding status, i.e., MCI or normal healthy control, based on which we identify the clinical label of a testing subject. In order to validate the effectiveness of the proposed method, we performed experiments on two different datasets and compared with state-of-the-art methods in the literature. We also analyzed the functional networks learned by DAE, estimated the functional connectivities by decoding hidden states in HMM, and investigated the estimated functional connectivities by means of a graph-theoretic approach. PMID:26774612

  16. Evaluation of three inverse problem models to quantify skin microcirculation using diffusion-weighted MRI

    NASA Astrophysics Data System (ADS)

    Cordier, G.; Choi, J.; Raguin, L. G.

    2008-11-01

    Skin microcirculation plays an important role in diseases such as chronic venous insufficiency and diabetes. Magnetic resonance imaging (MRI) can provide quantitative information with a better penetration depth than other noninvasive methods, such as laser Doppler flowmetry or optical coherence tomography. Moreover, successful MRI skin studies have recently been reported. In this article, we investigate three potential inverse models to quantify skin microcirculation using diffusion-weighted MRI (DWI), also known as q-space MRI. The model parameters are estimated based on nonlinear least-squares (NLS). For each of the three models, an optimal DWI sampling scheme is proposed based on D-optimality in order to minimize the size of the confidence region of the NLS estimates and thus the effect of the experimental noise inherent to DWI. The resulting covariance matrices of the NLS estimates are predicted by asymptotic normality and compared to the ones computed by Monte-Carlo simulations. Our numerical results demonstrate the effectiveness of the proposed models and corresponding DWI sampling schemes as compared to conventional approaches.

  17. 75 FR 57024 - Meeting of the Presidential Advisory Council on HIV/AIDS

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-17

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Meeting of the Presidential Advisory Council on HIV/AIDS... on HIV/AIDS (PACHA) will hold a meeting. The meeting will be open to the public. DATES: The meeting..., Presidential Advisory Council on HIV/AIDS, Department of Health and Human Services, 200 Independence Avenue, SW...

  18. Presidential Green Chemistry Challenge: 2001 Academic Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2001 award winner, Professor Chao-Jun Li, uses metal catalysts in water to carry out chemical reactions that used to need both an oxygen-free atmosphere and hazardous organic solvents.

  19. Presidential Green Chemistry Challenge: 2002 Academic Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2002 award winner, Professor Eric J. Beckman, developed fluorine-free detergents that help supercritical carbon dioxide (CO2) dissolve many chemicals, so it can be a solvent for industrial processes.

  20. 36 CFR § 1280.90 - What are the rules of conduct while visiting the Presidential libraries?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... while visiting the Presidential libraries? § 1280.90 Section § 1280.90 Parks, Forests, and Public... Additional Rules Apply for Use of Facilities in Presidential Libraries? § 1280.90 What are the rules of conduct while visiting the Presidential libraries? In addition to the rules in Subpart A, when visiting...

  1. Presidential Green Chemistry Challenge: 2005 Small Business Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2005 award winner, Metabolix, used biotechnology to develop microorganisms that produce polyhydroxyalkanoates: natural, biodegradable plastics with a range of environmental benefits.

  2. 36 CFR § 1280.94 - When do Presidential libraries allow other groups to use their public areas for events?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 36 Parks, Forests, and Public Property 3 2013-07-01 2012-07-01 true When do Presidential libraries... FACILITIES What Additional Rules Apply for Use of Facilities in Presidential Libraries? § 1280.94 When do Presidential libraries allow other groups to use their public areas for events? (a) Although Presidential...

  3. Sigma model Q-balls and Q-stars

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Verbin, Y.

    2007-10-15

    A new kind of Q-balls is found: Q-balls in a nonlinear sigma model. Their main properties are presented together with those of their self-gravitating generalization, sigma model Q-stars. A simple special limit of solutions which are bound by gravity alone ('sigma stars') is also discussed briefly. The analysis is based on calculating the mass, global U(1) charge and binding energy for families of solutions parametrized by the central value of the scalar field. Two kinds (differing by the potential term) of the new sigma model Q-balls and Q-stars are analyzed. They are found to share some characteristics while differing inmore » other respects like their properties for weak central scalar fields which depend strongly on the form of the potential term. They are also compared with their ordinary counterparts and although similar in some respects, significant differences are found like the existence of an upper bound on the central scalar field. A special subset of the sigma model Q-stars contains those which do not possess a flat space limit. Their relation with sigma star solutions is discussed.« less

  4. Presidential Green Chemistry Challenge: 2001 Small Business Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2001 award winner, EDEN Bioscience, discovered and commercialized harpins: nontoxic, naturally occurring, biodegradable proteins that activate a plant's defense and growth mechanisms.

  5. Presidential Green Chemistry Challenge: 2013 Academic Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2013 award winner, Prof Richard P. Wool of the University of Delaware, created high-performance materials using vegetable oils, feathers, and flax. Can be used as adhesives, composites, foams, and circuit boards.

  6. Presidential Green Chemistry Challenge: 2016 Academic Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2016 award winner, Professor Chirik, discovered a class of catalysts used to produce silicones for consumer goods without using hard-to-mine platinum (less mining, reduces costs, greenhouse gas emissions, and waste).

  7. Examining a New Method to Studying Velopharyngeal Structures in a Child With 22q11.2 Deletion Syndrome.

    PubMed

    Kollara, Lakshmi; Schenck, Graham; Jaskolka, Michael; Perry, Jamie L

    2017-04-14

    To date, no studies have imaged the velopharynx in children with 22q11.2 deletion syndrome (22q11.2 DS) without the use of sedation. Dysmorphology in velopharyngeal structures has been shown to have significant negative implications on speech among these individuals. This single case study was designed to assess the feasibility of a child-friendly magnetic resonance imaging (MRI) scanning protocol in this clinically challenging population and to determine the utility of this MRI protocol for future work in this area. One 6-year-old White girl diagnosed with 22q11.2 DS was imaged using a child-friendly, nonsedated MRI protocol. Quantitative and qualitative measures of the velopharyngeal area and associated structures were evaluated, and comparisons were made to age-matched control subjects with normal velopharyngeal anatomy. MRI data were successfully obtained using the child-friendly scanning protocol in the subject in the present study. Quantitative and qualitative differences of the levator muscle and associated velopharyngeal structures were noted. Using these MRI and structural analyses methods, insights related to muscle morphology can be obtained and considered as part of the research and clinical examination of children with 22q11.2 DS. The imaging protocol described in this study presents an effective means to counteract difficulties in imaging young children.

  8. CAIPIRINHA accelerated SPACE enables 10-min isotropic 3D TSE MRI of the ankle for optimized visualization of curved and oblique ligaments and tendons.

    PubMed

    Kalia, Vivek; Fritz, Benjamin; Johnson, Rory; Gilson, Wesley D; Raithel, Esther; Fritz, Jan

    2017-09-01

    To test the hypothesis that a fourfold CAIPIRINHA accelerated, 10-min, high-resolution, isotropic 3D TSE MRI prototype protocol of the ankle derives equal or better quality than a 20-min 2D TSE standard protocol. Following internal review board approval and informed consent, 3-Tesla MRI of the ankle was obtained in 24 asymptomatic subjects including 10-min 3D CAIPIRINHA SPACE TSE prototype and 20-min 2D TSE standard protocols. Outcome variables included image quality and visibility of anatomical structures using 5-point Likert scales. Non-parametric statistical testing was used. P values ≤0.001 were considered significant. Edge sharpness, contrast resolution, uniformity, noise, fat suppression and magic angle effects were without statistical difference on 2D and 3D TSE images (p > 0.035). Fluid was mildly brighter on intermediate-weighted 2D images (p < 0.001), whereas 3D images had substantially less partial volume, chemical shift and no pulsatile-flow artifacts (p < 0.001). Oblique and curved planar 3D images resulted in mildly-to-substantially improved visualization of joints, spring, bifurcate, syndesmotic, collateral and sinus tarsi ligaments, and tendons (p < 0.001, respectively). 3D TSE MRI with CAIPIRINHA acceleration enables high-spatial resolution oblique and curved planar MRI of the ankle and visualization of ligaments, tendons and joints equally well or better than a more time-consuming anisotropic 2D TSE MRI. • High-resolution 3D TSE MRI improves visualization of ankle structures. • Limitations of current 3D TSE MRI include long scan times. • 3D CAIPIRINHA SPACE allows now a fourfold-accelerated data acquisition. • 3D CAIPIRINHA SPACE enables high-spatial-resolution ankle MRI within 10 min. • 10-min 3D CAIPIRINHA SPACE produces equal-or-better quality than 20-min 2D TSE.

  9. Presidential Green Chemistry Challenge: 2012 Small Business Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2012 award winner, Elevance Renewable Sciences, used Nobel-prize-winning metathesis catalysis to produce high-value difunctional chemicals from renewable feedstocks including natural oils.

  10. Presidential Green Chemistry Challenge: 1998 Small Business Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 1998 award winner, PYROCOOL Technologies, developed a nontoxic, highly biodegradable fire extinguishing foam to replace ozone-depleting gases and foams that release toxic chemicals.

  11. Presidential Green Chemistry Challenge: 2006 Small Business Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2006 award winners, Arkon Consultants and NuPro Technologies, developed a safer processing system for flexographic printing that includes washout solvents and reclamation/recycling.

  12. Presidential Green Chemistry Challenge: 2011 Small Business Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2011 award winner, BioAmber, developed an integrated technology to produce large, commercial quantities of succinic acid by bacterial fermentation, replacing petroleum-based feedstocks.

  13. Transforming the Gray Factory: The Presidential Leadership of Charles M. Vest and the Architecture of Change at Massachusetts Institute of Technology

    ERIC Educational Resources Information Center

    Daas, Mahesh

    2013-01-01

    The single-site exemplar study presents an in-depth account of the presidential leadership of Charles M. Vest of MIT--the second longest presidency in the Institute's history--and his leadership team's journey between 1990 and 2004 into campus architectural changes that involved over a billion dollars, added a quarter of floor space to MIT's…

  14. 36 CFR 1253.3 - Presidential Libraries.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...) Lyndon Baines Johnson Library and Museum is located at 2313 Red River St., Austin, TX 78705-5702. The.... Hours for the Presidential libraries' research rooms are posted at http://www.archives.gov. [email protected] (k) George Bush Library is located at 1000 George Bush Drive West, College Station, TX...

  15. 36 CFR 1253.3 - Presidential Libraries.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) Lyndon Baines Johnson Library and Museum is located at 2313 Red River St., Austin, TX 78705-5702. The.... Hours for the Presidential libraries' research rooms are posted at http://www.archives.gov. [email protected] (k) George Bush Library is located at 1000 George Bush Drive West, College Station, TX...

  16. 36 CFR 1253.3 - Presidential Libraries.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) Lyndon Baines Johnson Library and Museum is located at 2313 Red River St., Austin, TX 78705-5702. The.... Hours for the Presidential libraries' research rooms are posted at http://www.archives.gov. [email protected] (k) George Bush Library is located at 1000 George Bush Drive West, College Station, TX...

  17. Presidential Green Chemistry Challenge: 1997 Small Business Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 1997 award winner, Legacy Systems, developed the Coldstrip process, which uses only water and oxygen to remove photoresist from silicon semiconductors. It replaces corrosive acids.

  18. Presidential Green Chemistry Challenge: 1996 Small Business Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 1996 award winner, Donlar, developed thermal polyaspartate, a nontoxic, biodegradable, biobased polymer made in a highly efficient process for use in agriculture, water treatment, etc.

  19. Presidential Green Chemistry Challenge: 2012 Academic Award (Coates)

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2012 award winner, Professor Geoffrey W. Coates, developed a family of catalysts that use carbon dioxide and carbon monoxide to make make polymers including polycarbonates.

  20. Presidential Green Chemistry Challenge: 2002 Small Business Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2002 award winner, SC Fluids, with Los Alamos National Laboratory, developed supercritical CO2 resist remover technology to clean residues from semiconductor wafers during manufacture.

  1. Needle position estimation from sub-sampled k-space data for MRI-guided interventions

    NASA Astrophysics Data System (ADS)

    Schmitt, Sebastian; Choli, Morwan; Overhoff, Heinrich M.

    2015-03-01

    MRI-guided interventions have gained much interest. They profit from intervention synchronous data acquisition and image visualization. Due to long data acquisition durations, ergonomic limitations may occur. For a trueFISP MRI-data acquisition sequence, a time sparing sub-sampling strategy has been developed that is adapted to amagnetic needle detection. A symmetrical and contrast rich susceptibility needle artifact, i.e. an approximately rectangular gray scale profile is assumed. The 1-D-Fourier transformed of a rectangular function is a sinc-function. Its periodicity is exploited by sampling only along a few orthogonal trajectories in k-space. Because a needle moves during intervention, its tip region resembles a rectangle in a time-difference image that is reconstructed from such sub-sampled k-spaces acquired at different time stamps. In different phantom experiments, a needle was pushed forward along a reference trajectory, which was determined from a needle holders geometric parameters. In addition, the trajectory of the needle tip was estimated by the method described above. Only ca. 4 to 5% of the entire k-space data was used for needle tip estimation. The misalignment of needle orientation and needle tip position, i.e. the differences between reference and estimated values, is small and even in its worst case less than 2 mm. The results show that the method is applicable under nearly real conditions. Next steps are addressed to the validation of the method for clinical data.

  2. Report on Alternative Models for Presidential Libraries Issued in Response to the Requirements of PL 110-404

    ERIC Educational Resources Information Center

    National Archives and Records Administration, 2009

    2009-01-01

    The Presidential Historical Records Preservation Act of 2008 [PL 110-404] requires that the Archivist of the United States submit to Congress a report on alternative models for Presidential archival depositories that: (1) Reduces the financial burden on the Federal Government; (2) Improves the preservation of Presidential records; and (3) Reduces…

  3. Quantitative chemical exchange saturation transfer (qCEST) MRI--RF spillover effect-corrected omega plot for simultaneous determination of labile proton fraction ratio and exchange rate.

    PubMed

    Sun, Phillip Zhe; Wang, Yu; Dai, ZhuoZhi; Xiao, Gang; Wu, Renhua

    2014-01-01

    Chemical exchange saturation transfer (CEST) MRI is sensitive to dilute proteins and peptides as well as microenvironmental properties. However, the complexity of the CEST MRI effect, which varies with the labile proton content, exchange rate and experimental conditions, underscores the need for developing quantitative CEST (qCEST) analysis. Towards this goal, it has been shown that omega plot is capable of quantifying paramagnetic CEST MRI. However, the use of the omega plot is somewhat limited for diamagnetic CEST (DIACEST) MRI because it is more susceptible to direct radio frequency (RF) saturation (spillover) owing to the relatively small chemical shift. Recently, it has been found that, for dilute DIACEST agents that undergo slow to intermediate chemical exchange, the spillover effect varies little with the labile proton ratio and exchange rate. Therefore, we postulated that the omega plot analysis can be improved if RF spillover effect could be estimated and taken into account. Specifically, simulation showed that both labile proton ratio and exchange rate derived using the spillover effect-corrected omega plot were in good agreement with simulated values. In addition, the modified omega plot was confirmed experimentally, and we showed that the derived labile proton ratio increased linearly with creatine concentration (p < 0.01), with little difference in their exchange rate (p = 0.32). In summary, our study extends the conventional omega plot for quantitative analysis of DIACEST MRI. Copyright © 2014 John Wiley & Sons, Ltd.

  4. CortiQ-based Real-Time Functional Mapping for Epilepsy Surgery.

    PubMed

    Kapeller, Christoph; Korostenskaja, Milena; Prueckl, Robert; Chen, Po-Ching; Lee, Ki Heyeong; Westerveld, Michael; Salinas, Christine M; Cook, Jane C; Baumgartner, James E; Guger, Christoph

    2015-06-01

    To evaluate the use of the cortiQ-based mapping system (g.tec medication engineering GmbH, Austria) for real-time functional mapping (RTFM) and to compare it to results from electrical cortical stimulation mapping (ESM) and functional magnetic resonance imaging (fMRI). Electrocorticographic activity was recorded in 3 male patients with intractable epilepsy by using cortiQ mapping system and analyzed in real time. Activation related to motor, sensory, and receptive language tasks was determined by evaluating the power of the high gamma frequency band (60-170 Hz). The sensitivity and specificity of RTFM were tested against ESM and fMRI results. "Next-neighbor" approach demonstrated [sensitivity/specificity %] (1) RTFM against ESM: 100.00/79.70 for hand motor; 100.00/73.87 for hand sensory; -/87 for language (it was not identified by the ESM); (2) RTFM against fMRI: 100.00/84.4 for hand motor; 66.70/85.35 for hand sensory; and 87.85/77.70 for language. The results of the quantitative "next-neighbor" RTFM evaluation were concordant to those from ESM and fMRI. The RTFM correlates well with localization of hand motor function provided by ESM and fMRI, which may offer added localization in the operating room and guidance for extraoperative ESM mapping. Real-time functional mapping correlates with fMRI language activation when ESM findings are negative. It has fewer limitations than ESM and greater flexibility in activation paradigms and measuring responses.

  5. Presidential Green Chemistry Challenge: 2010 Small Business Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2010 award winner, LS9, engineered microorganisms to convert fermentable sugars selectively to alkanes, olefins, fatty alcohols, or fatty esters, each in a single-unit biorefinery.

  6. Presidential Green Chemistry Challenge: 2008 Small Business Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2008 award winner, SiGNa Chemistry, stabilized highly reactive sodium and lithium by encapsulating them in porous, sand-like powder, maintaining their usefulness in synthetic reactions.

  7. The space exploration initiative

    NASA Technical Reports Server (NTRS)

    Priest, Pete

    1991-01-01

    A number of view graph charts are presented which outline the presentation. Outlined are reasons for going to Mars, why it is necessary to go to the Moon first, and the presidential decision on the space exploration initiative. Other representative charts are entitled: Lunar transportation system requirement drivers; Mars transportation system requirement drivers; National space policy goals; Exploration hardware needed; Mars mission profile; Science on the Moon and Mars; and Two independent reviews.

  8. Geometric validation of self-gating k-space-sorted 4D-MRI vs 4D-CT using a respiratory motion phantom

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yue, Yong, E-mail: yong.yue@cshs.org; Yang, Wensha; McKenzie, Elizabeth

    Purpose: MRI is increasingly being used for radiotherapy planning, simulation, and in-treatment-room motion monitoring. To provide more detailed temporal and spatial MR data for these tasks, we have recently developed a novel self-gated (SG) MRI technique with advantage of k-space phase sorting, high isotropic spatial resolution, and high temporal resolution. The current work describes the validation of this 4D-MRI technique using a MRI- and CT-compatible respiratory motion phantom and comparison to 4D-CT. Methods: The 4D-MRI sequence is based on a spoiled gradient echo-based 3D projection reconstruction sequence with self-gating for 4D-MRI at 3 T. Respiratory phase is resolved by usingmore » SG k-space lines as the motion surrogate. 4D-MRI images are reconstructed into ten temporal bins with spatial resolution 1.56 × 1.56 × 1.56 mm{sup 3}. A MRI-CT compatible phantom was designed to validate the performance of the 4D-MRI sequence and 4D-CT imaging. A spherical target (diameter 23 mm, volume 6.37 ml) filled with high-concentration gadolinium (Gd) gel is embedded into a plastic box (35 × 40 × 63 mm{sup 3}) and stabilized with low-concentration Gd gel. The phantom, driven by an air pump, is able to produce human-type breathing patterns between 4 and 30 respiratory cycles/min. 4D-CT of the phantom has been acquired in cine mode, and reconstructed into ten phases with slice thickness 1.25 mm. The 4D images sets were imported into a treatment planning software for target contouring. The geometrical accuracy of the 4D MRI and CT images has been quantified using target volume, flattening, and eccentricity. The target motion was measured by tracking the centroids of the spheres in each individual phase. Motion ground-truth was obtained from input signals and real-time video recordings. Results: The dynamic phantom has been operated in four respiratory rate (RR) settings, 6, 10, 15, and 20/min, and was scanned with 4D-MRI and 4D-CT. 4D-CT images have target

  9. The 1980 Presidential Debates. Special Issue.

    ERIC Educational Resources Information Center

    Ritter, Kurt W., Ed.

    1981-01-01

    Prepared by educators and researchers involved in argumentation and debate, the articles in this special journal issue are based upon the assumptions that presidential debates are important, are likely to continue, and are of unique interest to students, scholars, and practitioners of argument. The first two articles in the issue provide overviews…

  10. Let's Put "Debate" into "Presidential Debates."

    ERIC Educational Resources Information Center

    Benoit, William L.

    Presidential debates come in all shapes and sizes. The presence and length of opening statements and closing remarks, the opportunity and length of rebuttal, the nature of the questioner, and other factors have created a bewildering variety of formats. However, most scholars agree that these confrontations are not "really" debates but merely…

  11. U.S. Presidential Candidate camps debate sciences issues

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2000-10-01

    While budget surpluses, social security, and tax cut proposals have been major focuses during the U.S. presidential campaign between Texas Governor George W Bush and Vice President Al Gore, the candidates also have staked out a number of important issues related to Earth sciences and the environment. Two recent debates between representatives of the Bush and Gore camps have helped to clarify these positions. The Washington Science Policy Alliance presented a candidates forum on science and technology policy on October 5 at the American Association for the Advancement of Science (AAAS), in Washington, D.C. On September 26, the non-profit National Environmental Policy Institute (NEPI) held a debate on presidential politics and the environment at the National Press Club, also in Washington, D.C.

  12. Depicting the semicircular canals with inner-ear MRI: a comparison of the SPACE and TrueFISP sequences.

    PubMed

    Kojima, Shinya; Suzuki, Kazufumi; Hirata, Masami; Shinohara, Hiroyuki; Ueno, Eiko

    2013-03-01

    To assess the ability of magnetic resonance imaging (MRI) to depict the semicircular canals of the inner ear by comparing results from the sampling perfection with application-optimized contrasts by using different flip angle evolutions (SPACE) sequence with those from the true free induction with steady precession (TrueFISP) sequence. A 1.5-T MRI system was used to perform an in vivo study of 10 healthy volunteers and 17 patients. A three-point visual score was employed for assessing the depiction of the semicircular canals and facial and vestibulocochlear nerves and the contrast-to-noise ratio (CNR) was computed for the vestibule and pons on images with the SPACE and TrueFIPS sequences. There were no susceptibility artifact-related filling defects with the SPACE sequence. However, the TrueFISP sequence showed filling defects for at least one semicircular canal on both sides in seven cases for healthy subjects and in 10 cases for patients. The CNR with the SPACE sequence was significantly higher than with the TrueFISP sequence (P < 0.05). There was no statistically significant difference in depicting the facial and the vestibulocochlear nerves (P = 0.32). For the depiction of the semicircular canal, the SPACE sequence is superior to the TrueFISP sequence. Copyright © 2012 Wiley Periodicals, Inc.

  13. Presidential Green Chemistry Challenge: 2003 Small Business Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2003 award winner, AgraQuest, developed Serenade, an OMRI-listed biofungicide for fruits and vegetables based on Bacillus subtilis QST-713, a naturally occurring strain of bacteria.

  14. Presidential Green Chemistry Challenge: 2007 Small Business Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2007 award winner, NovaSterilis, invented a way to sterilize delicate biological materials such as graft tissue without harming them, using supercritical carbon dioxide and a peroxide.

  15. 36 CFR 1254.14 - Are some procedures in regional archives and Presidential libraries different from those in the...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... regional archives and Presidential libraries different from those in the Washington, DC, area? 1254.14... procedures in regional archives and Presidential libraries different from those in the Washington, DC, area... regional director of archival operations or Presidential library director indicates, you must follow the...

  16. 36 CFR 1254.14 - Are some procedures in regional archives and Presidential libraries different from those in the...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... regional archives and Presidential libraries different from those in the Washington, DC, area? 1254.14... procedures in regional archives and Presidential libraries different from those in the Washington, DC, area... regional director of archival operations or Presidential library director indicates, you must follow the...

  17. 36 CFR 1254.14 - Are some procedures in regional archives and Presidential libraries different from those in the...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... regional archives and Presidential libraries different from those in the Washington, DC, area? 1254.14... procedures in regional archives and Presidential libraries different from those in the Washington, DC, area... regional director of archival operations or Presidential library director indicates, you must follow the...

  18. 36 CFR 1254.14 - Are some procedures in regional archives and Presidential libraries different from those in the...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... regional archives and Presidential libraries different from those in the Washington, DC, area? 1254.14... procedures in regional archives and Presidential libraries different from those in the Washington, DC, area... regional director of archival operations or Presidential library director indicates, you must follow the...

  19. Student Engagement and Teacher Practices: Using Hillary Clinton's Presidential Campaign for Learning Purposes

    ERIC Educational Resources Information Center

    Gruber, Sibylle

    2011-01-01

    In this article, I reflect on the pedagogical decisions I made when I taught a course on gendered literacies during the 2008/2009 presidential campaign. I specifically focus on what I term the "Hillary" phenomenon, the media's often negative and unflattering portrayal of presidential candidate Hillary Clinton. I start with a brief…

  20. 76 FR 44052 - Submission for Review: Presidential Management Fellows (PMF); Nomination Form, OPM 1300

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-22

    ... accredited colleges and universities to nominate eligible graduate students to the Presidential Management... OFFICE OF PERSONNEL MANAGEMENT Submission for Review: Presidential Management Fellows (PMF); Nomination Form, OPM 1300 AGENCY: U.S. Office of Personnel Management. ACTION: 30-Day Notice and request for...

  1. Presidential Green Chemistry Challenge: 2009 Small Business Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2009 award winner, Virent, developed a water-based, catalytic method to make gasoline, diesel, or jet fuel from plant sugar, starch, or cellulose that requires little external energy.

  2. Presidential Green Chemistry Challenge: 1998 Academic Award (Trost)

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 1998 award winner Professor Barry M. Trost, developed the concept of atom economy: chemical reactions that do not waste atoms. This is a fundamental cornerstone of green chemistry.

  3. A Presidential Search Is Opportunity Knocking

    ERIC Educational Resources Information Center

    Funk, R. William

    2005-01-01

    When the inevitable change in presidential leadership takes place at a college or university, board members often think only of the additional demands the search will place on their hectic schedules. No other situation allows board members to contribute so positively and profoundly to the immediate and long-term welfare of the college or…

  4. Multidimensionally encoded magnetic resonance imaging.

    PubMed

    Lin, Fa-Hsuan

    2013-07-01

    Magnetic resonance imaging (MRI) typically achieves spatial encoding by measuring the projection of a q-dimensional object over q-dimensional spatial bases created by linear spatial encoding magnetic fields (SEMs). Recently, imaging strategies using nonlinear SEMs have demonstrated potential advantages for reconstructing images with higher spatiotemporal resolution and reducing peripheral nerve stimulation. In practice, nonlinear SEMs and linear SEMs can be used jointly to further improve the image reconstruction performance. Here, we propose the multidimensionally encoded (MDE) MRI to map a q-dimensional object onto a p-dimensional encoding space where p > q. MDE MRI is a theoretical framework linking imaging strategies using linear and nonlinear SEMs. Using a system of eight surface SEM coils with an eight-channel radiofrequency coil array, we demonstrate the five-dimensional MDE MRI for a two-dimensional object as a further generalization of PatLoc imaging and O-space imaging. We also present a method of optimizing spatial bases in MDE MRI. Results show that MDE MRI with a higher dimensional encoding space can reconstruct images more efficiently and with a smaller reconstruction error when the k-space sampling distribution and the number of samples are controlled. Copyright © 2012 Wiley Periodicals, Inc.

  5. Presidential Green Chemistry Challenge: 1999 Small Business Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 1999 award winner, Biofine, developed a process to convert waste cellulose in paper mill sludge, municipal solid waste, etc. into levulinic acid (LA), a building block for other chemicals.

  6. Presidential Green Chemistry Challenge: 2013 Small Business Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2013 award winner, Faraday Technology, Inc., process high-performance chrome coatings to be made from the less toxic, trivalent chromium. Reduce millions of pounds hexavalent chromium without comprising performance.

  7. 78 FR 49755 - Renewal of Charter for the Presidential Advisory Council on HIV/AIDS

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-15

    ... on HIV/ AIDS AGENCY: Office of HIV/AIDS and Infectious Disease Policy, Office of the Assistant... Presidential Advisory Council on HIV/ AIDS (PACHA; the Council) has been renewed. FOR FURTHER INFORMATION CONTACT: Ms. Caroline Talev, Public Health Assistant, Presidential Advisory Council on HIV/AID, Department...

  8. Romantic Democracy, Ronald Reagan, and Presidential Heroes.

    ERIC Educational Resources Information Center

    Fisher, Walter R.

    1982-01-01

    This practical criticism is written for communication scholars who seek further understanding of significant communication events. Believing that a romantic strain exists in American history/politics, this essay suggests characteristics of presidential heroes, relates Ronald Reagan's rhetoric to the romantic tradition, and compares his rhetoric…

  9. MRI-visible perivascular spaces in cerebral amyloid angiopathy and hypertensive arteriopathy

    PubMed Central

    Boulouis, Gregoire; Pasi, Marco; Auriel, Eitan; van Etten, Ellis S.; Haley, Kellen; Ayres, Alison; Schwab, Kristin M.; Martinez-Ramirez, Sergi; Goldstein, Joshua N.; Rosand, Jonathan; Viswanathan, Anand; Greenberg, Steven M.; Gurol, M. Edip

    2017-01-01

    Objective: To assess MRI-visible enlarged perivascular spaces (EPVS) burden and different topographical patterns (in the centrum semiovale [CSO] and basal ganglia [BG]) in 2 common microangiopathies: cerebral amyloid angiopathy (CAA) and hypertensive arteriopathy (HA). Methods: Consecutive patients with spontaneous intracerebral hemorrhage (ICH) from a prospective MRI cohort were included. Small vessel disease MRI markers, including cerebral microbleeds (CMBs), cortical superficial siderosis (cSS), and white matter hyperintensities (WMH), were rated. CSO-EPVS/BG-EPVS were assessed on a validated 4-point visual rating scale (0 = no EPVS, 1 = <10, 2 = 11–20, 3 = 21–40, and 4 = >40 EPVS). We tested associations of predefined high-degree (score >2) CSO-EPVS and BG-EPVS with other MRI markers in multivariable logistic regression. We subsequently evaluated associations with CSO-EPVS predominance (i.e., CSO-EPVS > BG-EPVS) and BG-EPVS predominance pattern (i.e., BG-EPVS > CSO-EPVS) in adjusted multinomial logistic regression (reference group, BG-EPVS = CSO-EPVS). Results: We included 315 patients with CAA-ICH and 137 with HA-ICH. High-degree CSO-EPVS prevalence was greater in CAA-related ICH vs HA-related ICH (43.8% vs 17.5%, p < 0.001). In multivariable logistic regression, high-degree CSO-EPVS was associated with lobar CMB (odds ratio [OR] 1.33, 95% confidence interval [CI] 1.10–1.61, p = 0.003) and cSS (OR 2.08, 95% CI 1.30–3.32, p = 0.002). Deep CMBs (OR 2.85, 95% CI 1.75–4.64, p < 0.0001) and higher WMH volume (OR 1.02, 95% CI 1.01–1.04, p = 0.010) were predictors of high-degree BG-EPVS. A CSO-EPVS–predominant pattern was more common in CAA-ICH than in HA-ICH (75.9% vs 39.4%, respectively, p < 0.0001). CSO-PVS predominance was associated with lobar CMB burden and cSS, while BG-EPVS predominance was associated with HA-ICH and WMH volumes. Conclusions: Different patterns of MRI-visible EPVS provide insights into the dominant underlying microangiopathy

  10. 36 CFR 1275.46 - Segregation and review; Senior Archival Panel; Presidential Materials Review Board.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...; Senior Archival Panel; Presidential Materials Review Board. 1275.46 Section 1275.46 Parks, Forests, and... Access by the Public § 1275.46 Segregation and review; Senior Archival Panel; Presidential Materials... a panel of senior archivists selected by the Archivist. The Panel shall then have the sole...

  11. 36 CFR 1275.46 - Segregation and review; Senior Archival Panel; Presidential Materials Review Board.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 3 2011-07-01 2011-07-01 false Segregation and review; Senior Archival Panel; Presidential Materials Review Board. 1275.46 Section 1275.46 Parks, Forests, and... Access by the Public § 1275.46 Segregation and review; Senior Archival Panel; Presidential Materials...

  12. 36 CFR 1280.94 - When do Presidential libraries allow other groups to use their public areas for events?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... libraries allow other groups to use their public areas for events? 1280.94 Section 1280.94 Parks, Forests... FACILITIES What Additional Rules Apply for Use of Facilities in Presidential Libraries? § 1280.94 When do Presidential libraries allow other groups to use their public areas for events? (a) Although Presidential...

  13. 36 CFR 1280.94 - When do Presidential libraries allow other groups to use their public areas for events?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... libraries allow other groups to use their public areas for events? 1280.94 Section 1280.94 Parks, Forests... FACILITIES What Additional Rules Apply for Use of Facilities in Presidential Libraries? § 1280.94 When do Presidential libraries allow other groups to use their public areas for events? (a) Although Presidential...

  14. 36 CFR 1280.94 - When do Presidential libraries allow other groups to use their public areas for events?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... libraries allow other groups to use their public areas for events? 1280.94 Section 1280.94 Parks, Forests... FACILITIES What Additional Rules Apply for Use of Facilities in Presidential Libraries? § 1280.94 When do Presidential libraries allow other groups to use their public areas for events? (a) Although Presidential...

  15. 36 CFR 1280.94 - When do Presidential libraries allow other groups to use their public areas for events?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... libraries allow other groups to use their public areas for events? 1280.94 Section 1280.94 Parks, Forests... FACILITIES What Additional Rules Apply for Use of Facilities in Presidential Libraries? § 1280.94 When do Presidential libraries allow other groups to use their public areas for events? (a) Although Presidential...

  16. Helium-3 MR q-space imaging with radial acquisition and iterative highly constrained back-projection.

    PubMed

    O'Halloran, Rafael L; Holmes, James H; Wu, Yu-Chien; Alexander, Andrew; Fain, Sean B

    2010-01-01

    An undersampled diffusion-weighted stack-of-stars acquisition is combined with iterative highly constrained back-projection to perform hyperpolarized helium-3 MR q-space imaging with combined regional correction of radiofrequency- and T1-related signal loss in a single breath-held scan. The technique is tested in computer simulations and phantom experiments and demonstrated in a healthy human volunteer with whole-lung coverage in a 13-sec breath-hold. Measures of lung microstructure at three different lung volumes are evaluated using inhaled gas volumes of 500 mL, 1000 mL, and 1500 mL to demonstrate feasibility. Phantom results demonstrate that the proposed technique is in agreement with theoretical values, as well as with a fully sampled two-dimensional Cartesian acquisition. Results from the volunteer study demonstrate that the root mean squared diffusion distance increased significantly from the 500-mL volume to the 1000-mL volume. This technique represents the first demonstration of a spatially resolved hyperpolarized helium-3 q-space imaging technique and shows promise for microstructural evaluation of lung disease in three dimensions. Copyright (c) 2009 Wiley-Liss, Inc.

  17. Presidential Green Chemistry Challenge: 2014 Small Business Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2014 award winner, Amyris, engineered yeast to make a chemical called farnesene, which is a building block hydrocarbon that can be converted into a renewable, drop-in replacement for petroleum diesel.

  18. Presidential Green Chemistry Challenge: 2000 Small Business Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2000 award winner, RevTech, developed a process to print top-quality labels directly on glass. Their Envirogluv inks have no heavy metals, have little to no VOCs, and are biodegradable.

  19. Presidential Green Chemistry Challenge: 2007 Greener Reaction Conditions Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2007 award winner, Headwaters Technology Innovation, developed a metal nanocatalyst to synthesize hydrogen peroxide directly from hydrogen and oxygen, eliminating hazardous chemicals.

  20. Presidential Green Chemistry Challenge: 2011 Greener Synthetic Pathways Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2011 award winner, Genomatica, is developing and commercializing sustainable basic and intermediate chemicals made from renewable feedstocks including sugars, biomass, and syngas.

  1. Q?rius: An innovative and new interactive educational space at the Smithsonian Institution's National Museum of Natural History, in Washington, D.C

    NASA Astrophysics Data System (ADS)

    Blankenbicker, R.

    2013-12-01

    The Fall of 2013 marks the opening of Q?rius ('curious'), a 10,000 square foot, interactive educational space at the Smithsonian Institution's National Museum of Natural History. Representing the 7 areas of the museum's research divisions, Q?rius includes a publicly accessible collection of over 6,000 natural history objects and multiple opportunities for visitors to engage themselves in natural history and the research conducted at the museum in various settings, including a lab, theater, and studio. A digital component to the space allows visitors to save parts of their experiences to a personal account, which they can later access remotely from their home or school. The space also serves as a tool for scientists to conduct outreach programs for museum visitors and for schools across the country through distance learning capabilities. Geology content for Q?rius was developed through collaboration between the Office of Education and Outreach and the Department of Mineral Sciences, as well as scientists and educators from outside agencies. Current experiences for the public include modeling plate tectonics and how they change rocks on small and large scales, identifying minerals in rocks, and using Earth to understand Martian geology. A school program adds the concept of drill cores and natural resources to the plate tectonics activity, which allows discussion about resource extraction. Developing experiences for Q?rius in all content areas took place over 2 phases; first, through taking prototypes into the museum exhibition halls to test with visitors through several iterations, and second in the new space, where all of the activities could be tested as a group and in the appropriate environment. By the time this abstract has been submitted, the official opening will not have occurred, though Q?rius will have been open for about 1 month by the time of the 2013 AGU annual conference, allowing us to further evaluate the development of the space.

  2. Gender differences in the structural connectome of the teenage brain revealed by generalized q-sampling MRI.

    PubMed

    Tyan, Yeu-Sheng; Liao, Jan-Ray; Shen, Chao-Yu; Lin, Yu-Chieh; Weng, Jun-Cheng

    2017-01-01

    The question of whether there are biological differences between male and female brains is a fraught one, and political positions and prior expectations seem to have a strong influence on the interpretation of scientific data in this field. This question is relevant to issues of gender differences in the prevalence of psychiatric conditions, including autism, attention deficit hyperactivity disorder (ADHD), Tourette's syndrome, schizophrenia, dyslexia, depression, and eating disorders. Understanding how gender influences vulnerability to these conditions is significant. Diffusion magnetic resonance imaging (dMRI) provides a non-invasive method to investigate brain microstructure and the integrity of anatomical connectivity. Generalized q-sampling imaging (GQI) has been proposed to characterize complicated fiber patterns and distinguish fiber orientations, providing an opportunity for more accurate, higher-order descriptions through the water diffusion process. Therefore, we aimed to investigate differences in the brain's structural network between teenage males and females using GQI. This study included 59 (i.e., 33 males and 26 females) age- and education-matched subjects (age range: 13 to 14 years). The structural connectome was obtained by graph theoretical and network-based statistical (NBS) analyses. Our findings show that teenage male brains exhibit better intrahemispheric communication, and teenage female brains exhibit better interhemispheric communication. Our results also suggest that the network organization of teenage male brains is more local, more segregated, and more similar to small-world networks than teenage female brains. We conclude that the use of an MRI study with a GQI-based structural connectomic approach like ours presents novel insights into network-based systems of the brain and provides a new piece of the puzzle regarding gender differences.

  3. Presidential Leadership in Decision-Making: A Study of Three Historically Black Colleges and Universities

    ERIC Educational Resources Information Center

    Brown, Ronald E. L.

    2010-01-01

    This study investigates presidential leadership in decision-making at three private Historically Black Colleges and Universities (HBCUs) and compares understandings of presidential power within and among the three colleges given their unique institutional contexts. The research questions guiding this study include. How do the presidents of 3…

  4. Presidential Green Chemistry Challenge: 2005 Designing Greener Chemicals Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2005 award winner, Archer Daniels Midland, developed Archer RC, a nonvolatile, biobased, reactive coalescent that replaces volatile organic coalescents in architectural latex paints.

  5. Presidential Green Chemistry Challenge: 2014 Greener Synthetic Pathways Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2014 award winner, Solazyme, engineered microalgae to produce oils tailored to customers’ needs that can mimic or enhance properties of traditional vegetable oils.

  6. Presidential Green Chemistry Challenge: 2014 Designing Greener Chemicals Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2014 award winner, The Solberg Company, replaced fluorinated surfactants in its firefighting foam concentrates with a blend of non-fluorinated surfactants and sugars.

  7. Measuring patients' satisfaction with their anti-TNF treatment in severe Crohn's disease: scoring and psychometric validation of the Satisfaction for PAtients in Crohn's diseasE Questionnaire (SPACE-Q(©)).

    PubMed

    Gilet, Hélène; Arnould, Benoit; Fofana, Fatoumata; Clerson, Pierre; Colombel, Jean-Frédéric; D'Hondt, Olivier; Faure, Patrick; Hagège, Hervé; Nachury, Maria; Nahon, Stéphane; Tucat, Gilbert; Vandromme, Luc; Cazala-Telinge, Ines; Thibout, Emmanuel

    2014-01-01

    Severe Crohn's disease management includes anti-tumor necrosis factor (anti-TNF) drugs that differ from early-stage treatments regarding efficacy, safety, and convenience. This study aimed to finalize and psychometrically validate the Satisfaction for PAtients in Crohn's diseasE Questionnaire (SPACE-Q(©)), developed to measure satisfaction with anti-TNF treatment in patients with severe Crohn's disease. A total of 279 patients with severe Crohn's disease receiving anti-TNF therapy completed the SPACE-Q 62-item pilot version at inclusion and 12 and 13 weeks after first anti-TNF injection. The final SPACE-Q scoring was defined using multitrait and regression analyses and clinical relevance considerations. Psychometric validation included clinical validity against Harvey-Bradshaw score, concurrent validity against Treatment Satisfaction Questionnaire for Medication (TSQM), internal consistency reliability, test-retest reliability, and responsiveness against the patient global impression of change (PGIC). Quality of completion was good (55%-67% of patients completed all items). Four items were removed from the questionnaire. Eleven scores were defined within the final 58-item SPACE-Q: disease control; symptoms, anal symptoms, and quality of life transition scales; tolerability; convenience; expectation confirmation toward efficacy, side effects, and convenience; satisfaction with treatment; and motivation. Scores met standards for concurrent validity (correlation between SPACE-Q satisfaction with treatment and TSQM satisfaction scores =0.59), internal consistency reliability (Cronbach's α=0.67-0.93), test-retest reliability (intraclass correlations =0.62-0.91), and responsiveness (improvement in treatment experience assessed by the SPACE-Q for patients reporting improvement on the PGIC). Significantly different mean scores were observed between groups of patients with different Harvey-Bradshaw disease severity scores. The SPACE-Q is a valid, reliable, and responsive

  8. Presidential Green Chemistry Challenge: 2016 Small Business Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2016 award winner, Verdezyne, developed a yeast to produce USDA Certified Biobased dodecanedioic acid (DDDA) used to make high performance nylon 6,12. Lower greenhouse gas emissions, no high temperature or nitric acid

  9. Presidential Green Chemistry Challenge: 1997 Designing Greener Chemicals Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 1997 award winner, Albright & Wilson Americas, discovered that tetrakis(hydroxymethyl)phosphonium sulfate, THPS, is an effective, safer biocide for use in industrial water systems.

  10. Presidential Green Chemistry Challenge: 2006 Greener Synthetic Pathways Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2006 award winner, Merck, discovered the asymmetric catalytic hydrogenation of unprotected enamines to make beta-amino acids. Merck applied this to synthesize sitagliptin (Januvia).

  11. Presidential Green Chemistry Challenge: 2004 Greener Reaction Conditions Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2004 award winner, Buckman Laboratories International, developed Optimyze technology, which uses an esterase enzyme to remove sticky contaminants from paper products prior to recycling.

  12. Presidential Green Chemistry Challenge: 2001 Greener Synthetic Pathways Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2001 award winners, Bayer Corporation and Bayer AG, developed a waste-free manufacturing process for sodium iminodisuccinate (Baypure CX), a biodegradable, nontoxic chelating agent.

  13. Presidential Green Chemistry Challenge: 2007 Designing Greener Chemicals Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2007 award winner, Cargill, developed biobased polyols for polyurethane applications, including flexible foams. Cargill makes BiOH polyols from vegetable oils, not petroleum products.

  14. Presidential Green Chemistry Challenge: 1998 Greener Reaction Conditions Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 1998 award winner, Argonne National Laboratory, developed an efficient, membrane-based process to synthesize lactate esters from sugars. These esters can replace toxic solvents.

  15. Presidential Green Chemistry Challenge: 2002 Greener Reaction Conditions Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2002 award winner, Cargill Dow, developed the NatureWorks process to make biobased, compostable, and recyclable polylactic acid polymers for fibers and plastic packaging.

  16. Presidential Green Chemistry Challenge: 2010 Designing Greener Chemicals Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2010 award winner, Clarke, developed Natular, a plaster matrix that encapsulates the pesticide spinosad, slowly releasing it into water and effectively controlling mosquito larvae.

  17. 36 CFR § 1254.14 - Are some procedures in regional archives and Presidential libraries different from those in the...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... regional archives and Presidential libraries different from those in the Washington, DC, area? § 1254.14... procedures in regional archives and Presidential libraries different from those in the Washington, DC, area... regional director of archival operations or Presidential library director indicates, you must follow the...

  18. Presidential Green Chemistry Challenge: 1999 Greener Synthetic Pathways Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 1999 award winner, Lilly Research Laboratories, developed a low-waste drug synthesis using yeast for a stereospecific reduction, reducing solvent amounts, and replacing chromium oxide.

  19. Presidential Green Chemistry Challenge: 2004 Designing Greener Chemicals Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2004 award winner, Engelhard Corporation, developed a wide range of environmentally friendly Rightfit azo pigments that contain calcium, strontium, or barium instead of heavy metals.

  20. Presidential Green Chemistry Challenge: 2002 Designing Greener Chemicals Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2002 award winner, Chemical Specialties, developed an alkaline copper quaternary wood preservative to replace chromated copper arsenate preservative phased out due to risk to children.

  1. Presidential Green Chemistry Challenge: 2000 Greener Synthetic Pathways Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2000 award winner, Roche Colorado, developed a greener synthesis for gancyclovir (Cytovene, a potent antiviral drug) that uses a second-generation Guanine Triester (GTE) process.

  2. Presidential Green Chemistry Challenge: 2004 Greener Synthetic Pathways Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2004 award winner, Bristol-Myers Squibb, manufactures paclitaxel, the active ingredient in the anticancer drug, Taxol, using plant cell fermentation and extraction to replace synthesis.

  3. Presidential Green Chemistry Challenge: 2003 Greener Reaction Conditions Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2003 award winner, DuPont, developed a genetically engineered microorganism jointly with Genencor International to manufacture 1,3-propanediol, a building block for Sorona polyester.

  4. Presidential Green Chemistry Challenge: 2011 Greener Reaction Conditions Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2011 award winner, Kraton Performance Polymers, developed halogen-free, high-flow NEXAR polymer membranes using less solvent that save energy during reverse osmosis to desalinate water.

  5. Presidential Green Chemistry Challenge: 1999 Greener Reaction Conditions Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 1999 award winner, Nalco Chemical Co., developed homogeneous dispersion polymerization with water as the solvent to make polymers to treat water in industrial and municipal operations.

  6. Presidential Green Chemistry Challenge: 1997 Greener Synthetic Pathways Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 1997 award winner, BHC Company, developed a highly atom-efficient method to make ibuprofen, a common painkiller, using three catalytic steps instead of six stoichiometric ones.

  7. Presidential Green Chemistry Challenge: 2011 Designing Greener Chemicals Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2011 award winner, Sherwin-Williams, developed water-based acrylic alkyd paints with VOCs that can be made from recycled soda bottle (PET), acrylics, and soybean oil.

  8. Presidential Green Chemistry Challenge: 2009 Greener Synthetic Pathways Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2009 award winner, Eastman Chemical Co., makes esters for emollients and emulsifiers in cosmetics with immobilized enzymes, saving energy and avoiding strong acids and organic solvents.

  9. Presidential Green Chemistry Challenge: 2010 Greener Reaction Conditions Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2010 award winners, Merck & Co. and Codexis, developed an enzymatic synthesis for sitagliptin (Januvia) that reduces waste, improves yield and safety, and eliminates a metal catalyst.

  10. Presidential Green Chemistry Challenge: 2007 Greener Synthetic Pathways Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2007 award winners, Professor Kaichang Li, Columbia Forest Products, and Hercules, developed an adhesive for wood composites based on soy flour instead of resins with formaldehyde.

  11. Presidential Green Chemistry Challenge: 2001 Designing Greener Chemicals Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2001 award winner, PPG Industries, developed cationic electrodeposition coatings with yttrium that resist corrosion in automobiles. Yttrium is a safe replacement for lead in this use.

  12. Presidential Green Chemistry Challenge: 2012 Designing Greener Chemicals Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2012 award winner, Buckman International, developed Maximyze enzymes that modify the cellulose in wood fibers to increase binding between fibers in paper and improve paper strength.

  13. Presidential Green Chemistry Challenge: 1999 Designing Greener Chemicals Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 1999 award winner, Dow AgroSciences, developed spinosad, a highly selective, low-toxicity, nonpersistant insecticide made by a soil microorganism. It controls many chewing insect pests.

  14. Presidential Green Chemistry Challenge: 2012 Greener Reaction Conditions Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2012 award winner, Cytec Industries, developed the MAX HT sodalite scale inhibitor for heat exchangers and pipes in the Bayer process, which converts bauxite into alumina.

  15. Presidential Green Chemistry Challenge: 2009 Greener Reaction Conditions Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2009 award winner, CEM Corporation, developed a fast, automated analytical process using less toxic reagents and less energy to distinguish protein from the food adulterant, melamine.

  16. 36 CFR § 1253.3 - Presidential Libraries.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) Lyndon Baines Johnson Library and Museum is located at 2313 Red River St., Austin, TX 78705-5702. The... Libraries. Hours for the Presidential libraries' research rooms are posted at http://www.archives.gov. [email protected] (k) George Bush Library is located at 1000 George Bush Drive West, College Station, TX...

  17. Prof. Hanna Neumann's Inaugural Presidential Address, 1966

    ERIC Educational Resources Information Center

    Neumann, Hanna

    2017-01-01

    Prof. Hanna Neumann gave the Presidential Address at Australian Association of Mathematics Teachers inaugural conference in 1966. The conference was held at Monash University and had the theme of "mathematical unity". In this address, Prof. Neumann described some features of the teaching of mathematics in schools. While she did not know…

  18. Beyond Textbook Civics/A Presidential Election Storypath

    ERIC Educational Resources Information Center

    McGuire, Margit E.; Nicholson, Karen; Rand, Allan

    2017-01-01

    Civics education shouldn't be confined to dusty textbooks, as evidenced by this assortment of projects. In one unit, elementary students play out the presidential election--from campaigning to inauguration day--using the Storypath approach. In another project, 5th graders explore the controversy about Confederate monuments by studying a local…

  19. Presidential Leadership for Prevention. E-Fact Sheet

    ERIC Educational Resources Information Center

    Higher Education Center for Alcohol, Drug Abuse, and Violence Prevention, 2010

    2010-01-01

    Most of the colleges and universities that have received U.S. Department of Education Models of Exemplary, Effective, and Promising Alcohol or Other Drug Abuse Prevention Programs on College Campuses grants credit strong presidential leadership for the success of their prevention efforts. With many colleges and universities currently facing budget…

  20. White House Communications Agency (WHCA) Presidential Voice Communications Rack Mount System Mechanical Drawing Package

    DTIC Science & Technology

    2015-12-01

    Rack Mount System Mechanical Drawing Package by Steven P Callaway Approved for public release; distribution unlimited...Laboratory White House Communications Agency (WHCA) Presidential Voice Communications Rack Mount System Mechanical Drawing Package by Steven P...Note 3. DATES COVERED (From - To) 04/2013 4. TITLE AND SUBTITLE White House Communications Agency (WHCA) Presidential Voice Communications Rack

  1. 78 FR 14799 - Solicitation of Nominations to the Presidential Advisory Council on HIV/AIDS

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-07

    ... Council on HIV/AIDS AGENCY: Office of the Assistant Secretary for Health, Office of the Secretary... Service Act (42 U.S.C. 217a. The Presidential Advisory Council on HIV/AIDS (referred to as PACHA and/or... as members of the Presidential Advisory Council on HIV/AIDS (PACHA). The PACHA is a federal advisory...

  2. Presidential Green Chemistry Challenge: 1998 Greener Synthetic Pathways Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 1998 award winner, Flexsys America, developed nucleophilic aromatic substitution for hydrogen to eliminate waste from a common reaction and to produce 4-ADPA, a high-volume chemical.

  3. Presidential Green Chemistry Challenge: 2005 Greener Reaction Conditions Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2005 award winner, BASF, invented a one-component, urethane acrylate oligomer primer system for automobile refinishing that is UV-curable, has VOCs, and is free of diisocyanates.

  4. Presidential Green Chemistry Challenge: 2001 Greener Reaction Conditions Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2001 award winner, Novozymes North America, developed BioPreparation, an enzyme technology to separate natural waxes, oils, and contaminants from cotton before it is made into fabric.

  5. Presidential Green Chemistry Challenge: 1997 Greener Reaction Conditions Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 1997 award winner, Imation, developed DryView Imaging Systems, which use a special photographic film for medical imaging that replaces hazardous developer chemicals and water with heat.

  6. Presidential Green Chemistry Challenge: 2000 Designing Greener Chemicals Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2000 award winner, Dow AgroSciences, developed Sentricon to eliminate termites with bait applied only where termites are active; it replaces widespread applications of pesticide to soil.

  7. Presidential Green Chemistry Challenge: 2008 Designing Greener Chemicals Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2008 award winner, Dow AgroSciences, used an artificial neural network to discover spinetoram, an improved spinosad biopesticide to replace organophosphates for key pests of fruit trees.

  8. Presidential Green Chemistry Challenge: 2006 Greener Reaction Conditions Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2006 award winner, Codexis, directed the evolution of three designer enzymes to produce the key chiral building block for atorvastatin, the active ingredient in the drug Lipitor.

  9. Presidential Green Chemistry Challenge: 1996 Designing Greener Chemicals Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 1996 award winner, Rohm and Haas, developed Sea-Nine, a marine antifoulant to control plants and animals on ship hulls. Sea-Nine replaces persistent, toxic organotin antifoulants.

  10. The Chancellor's Role in a Presidential Transition

    ERIC Educational Resources Information Center

    Appleton, James R.; Dorsey, Stuart

    2009-01-01

    Successful transitions involving a formal role for the former president, such as chancellor, are rare enough that the authors think theirs is an exceptional experience and is worth sharing, especially given the bulge of presidential retirements anticipated over the next decade. The authors believe that this model of transition can be successful,…

  11. Flip-Flopping, Presidential Politics, and Abraham Lincoln

    ERIC Educational Resources Information Center

    Neumann, Dave

    2012-01-01

    The American public can count on a few things during the presidential election season. First, candidates will take a moral high ground and forswear mudslinging. Before long however, they will proceed to engage in nasty accusations against their opponents. A vibrant democracy ought to welcome carefully thought-out views that, when intentionally…

  12. Presidential Green Chemistry Challenge: 2008 Greener Reaction Conditions Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2008 award winner, Nalco Company, developed 3D TRASAR technology to monitor the condition of cooling water continuously and add chemicals only when needed, saving water and energy.

  13. Presidential Green Chemistry Challenge: 1996 Greener Synthetic Pathways Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 1996 award winner, Monsanto Company, developed a safer synthesis for DSIDA, a key building block for the herbicide RoundUp. The synthesis uses no ammonia, cyanide, or formaldehyde.

  14. Mapping immune cell infiltration using restricted diffusion MRI.

    PubMed

    Yeh, Fang-Cheng; Liu, Li; Hitchens, T Kevin; Wu, Yijen L

    2017-02-01

    Diffusion MRI provides a noninvasive way to assess tissue microstructure. Based on diffusion MRI, we propose a model-free method called restricted diffusion imaging (RDI) to quantify restricted diffusion and correlate it with cellularity. An analytical relation between q-space signals and the density of restricted spins was derived to quantify restricted diffusion. A phantom study was conducted to investigate the performance of RDI, and RDI was applied to an animal study to assess immune cell infiltration in myocardial tissues with ischemia-reperfusion injury. Our phantom study showed a correlation coefficient of 0.998 between cell density and the restricted diffusion quantified by RDI. The animal study also showed that the high-value regions in RDI matched well with the macrophage infiltration areas in the H&E stained slides. In comparison with diffusion tensor imaging (DTI), RDI exhibited its outperformance to detect macrophage infiltration and delineate inflammatory myocardium. RDI can be used to reveal cell density and detect immune cell infiltration. RDI exhibits better specificity than the diffusivity measurement derived from DTI. Magn Reson Med 77:603-612, 2017. © 2016 International Society for Magnetic Resonance in Medicine. © 2016 International Society for Magnetic Resonance in Medicine.

  15. Presidential Commission on Risk Assessment and Risk Management

    EPA Science Inventory

    September 26, 1997. The Presidential/Congressional Commission on Risk Assessment and Risk Management, which was mandated as part of the Clean Air Act Amendments of 1990, was disbanded on August 31, 1997, with some staff work continuing into September. The reports and asso...

  16. Open-flavor charm and bottom s q q ¯ Q ¯ and q q q ¯ Q ¯ tetraquark states

    NASA Astrophysics Data System (ADS)

    Chen, Wei; Chen, Hua-Xing; Liu, Xiang; Steele, T. G.; Zhu, Shi-Lin

    2017-06-01

    We provide comprehensive investigations for the mass spectrum of exotic open-flavor charmed/bottom s q q ¯ c ¯ , q q q ¯ c ¯ , s q q ¯ b ¯ , q q q ¯ b ¯ tetraquark states with various spin-parity assignments JP=0+,1+,2+ and 0- , 1- in the framework of QCD sum rules. In the diquark configuration, we construct the diquark-antidiquark interpolating tetraquark currents using the color-antisymmetric scalar and axial-vector diquark fields. The stable mass sum rules are established in reasonable parameter working ranges, which are used to give reliable mass predictions for these tetraquark states. We obtain the mass spectra for the open-flavor charmed/bottom s q q ¯c ¯, q q q ¯c ¯, s q q ¯b ¯, q q q ¯b ¯ tetraquark states with various spin-parity quantum numbers. In addition, we suggest searching for exotic doubly-charged tetraquarks, such as [s d ][u ¯ c ¯ ]→Ds(*)-π- in future experiments at facilities such as BESIII, BelleII, PANDA, LHCb, and CMS, etc.

  17. How has the presidential election affected young Americans?

    PubMed

    DeJonckheere, Melissa; Fisher, Andre; Chang, Tammy

    2018-01-01

    The 2016 presidential election season and subsequent political events have had physical and emotional impacts on youth. We collected qualitative insights from 14 to 24 year olds across the US related to these events over time. Open-ended probes were sent via text message at three time points before and after the 2016 presidential election. The majority of youth reported emotional stress during all three time points, and female participants were significantly more likely to experience emotional responses. White participants were more likely to report negative symptoms than their peers both pre-election and at 4-months post-election. While preliminary, the results indicate that feelings of stress, anxiety, and fear have persisted in the months following the election, particularly for young women. Additional research is needed to examine the long-term effects of political events on the emotional and physical health of youth.

  18. Presidential Green Chemistry Challenge: 2008 Greener Synthetic Pathways Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2008 award winner, Battelle, developed a biobased soy toner for laser printers and copiers. The technology saves energy and improves de-inking, allowing more paper fiber to be recycled.

  19. Presidential Green Chemistry Challenge: 2010 Greener Synthetic Pathways Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2010 award winners, Dow and BASF, jointly developed a route to make propylene oxide from hydrogen peroxide that eliminates almost all waste and greatly reduces water and energy use.

  20. Presidential Green Chemistry Challenge: 2006 Designing Greener Chemicals Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2006 award winner, S.C. Johnson & Son, developed Greenlist, a rating system for environmental and health effects of ingredients. SC Johnson uses it to reformulate many of its products.

  1. Presidential Green Chemistry Challenge: 2016 Greener Synthetic Pathways Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2016 award winners, Albemarle and CB&I, developed a safer technology to produce alkylate, a clean gasoline component by replacing liquid acid catalysts with a lower environmental impact catalyst

  2. Presidential Green Chemistry Challenge: 1998 Designing Greener Chemicals Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 1998 award winner, Rohm and Haas, developed CONFIRM, a highly selective, reduced risk insecticide that disrupts the molting process of caterpillar pests in turf and a variety of crops.

  3. Presidential Green Chemistry Challenge: 2003 Designing Greener Chemicals Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2003 award winner, Shaw Industries, developed EcoWorx carpet tiles with a backing that uses less toxic materials. The carpet tile fiber and backing are readily separated for recycling.

  4. Low-field MRI can be more sensitive than high-field MRI

    NASA Astrophysics Data System (ADS)

    Coffey, Aaron M.; Truong, Milton L.; Chekmenev, Eduard Y.

    2013-12-01

    MRI signal-to-noise ratio (SNR) is the key factor for image quality. Conventionally, SNR is proportional to nuclear spin polarization, which scales linearly with magnetic field strength. Yet ever-stronger magnets present numerous technical and financial limitations. Low-field MRI can mitigate these constraints with equivalent SNR from non-equilibrium ‘hyperpolarization' schemes, which increase polarization by orders of magnitude independently of the magnetic field. Here, theory and experimental validation demonstrate that combination of field independent polarization (e.g. hyperpolarization) with frequency optimized MRI detection coils (i.e. multi-turn coils using the maximum allowed conductor length) results in low-field MRI sensitivity approaching and even rivaling that of high-field MRI. Four read-out frequencies were tested using samples with identical numbers of 1H and 13C spins. Experimental SNRs at 0.0475 T were ∼40% of those obtained at 4.7 T. Conservatively, theoretical SNRs at 0.0475 T 1.13-fold higher than those at 4.7 T were possible despite an ∼100-fold lower detection frequency, indicating feasibility of high-sensitivity MRI without technically challenging, expensive high-field magnets. The data at 4.7 T and 0.0475 T was obtained from different spectrometers with different RF probes. The SNR comparison between the two field strengths accounted for many differences in parameters such as system noise figures and variations in the probe detection coils including Q factors and coil diameters.

  5. 76 FR 9760 - Presidential Academies for Teaching of American History and Civics; Office of Innovation and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-22

    ... 1965, a broader program, Effective Teaching and Learning for a Well-Rounded Education, that would... DEPARTMENT OF EDUCATION Presidential Academies for Teaching of American History and Civics; Office of Innovation and Improvement; Overview Information; Presidential Academies for Teaching of American...

  6. Power Indices and U.S. Presidential Elections

    ERIC Educational Resources Information Center

    Colen, Yong S.; Navaratna, Channa; Colen, Jung; Kim, Jinho

    2012-01-01

    The 2012 U.S. presidential election is the perfect opportunity to present a timely civics lesson on how a U.S. president is elected. More important, it offers opportunities for students to reason mathematically about election issues--for example, about how much time and resources the candidates should invest in particular states. The results of…

  7. Discover Presidential Log Cabins. Teacher's Discussion Guide.

    ERIC Educational Resources Information Center

    National Park Service (Dept. of Interior), Washington, DC.

    Discover Presidential Log Cabins is a set of materials designed to help educate 6-8 grade students about the significance of three log cabin sites occupied by George Washington, Ulysses Grant, Abraham Lincoln, and Theodore Roosevelt. This teacher's discussion guide is intended for use as part of a larger, comprehensive social studies program, and…

  8. Editorials and Foreign Affairs in the 1972 Presidential Campaign

    ERIC Educational Resources Information Center

    Myers, David S.

    1974-01-01

    Results support the hypothesis that foreign affairs issues decided the outcome of the 1972 Presidential election and even in papers which endorsed George McGovern the editorials on foreign affairs favored Richard Nixon. (RB)

  9. Presidential Green Chemistry Challenge: 2000 Greener Reaction Conditions Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2000 award winners, Bayer and Bayer AG, Covestro, developed high-performance, water-based, two-component polyurethane (PU) coatings that eliminate most or all VOCs and HAPs in other PU coatings.

  10. Presidential Green Chemistry Challenge: 2002 Greener Synthetic Pathways Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2002 award winner, Pfizer, improved its synthesis of sertraline, the active ingredient in its drug, Zoloft, to double the yield and reduce the use of raw materials, energy, and water.

  11. Presidential Green Chemistry Challenge: 2003 Greener Synthetic Pathways Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2003 winner, Sud-Chemie, developed a synthesis for solid oxide catalysts used to make hydrogen and clean fuels. The process creates little wastewater, no nitrates, and no or little NOx.

  12. Presidential Green Chemistry Challenge: 2013 Designing Greener Chemicals Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2013 award winner, Cargill, Inc., developed a vegetable-oil-based transformer fluid that is much less flammable, provides superior performance, is less toxic, and has a substantially lower carbon footprint.

  13. Presidential Address: Turbulent magnetic fields in the Sun

    NASA Astrophysics Data System (ADS)

    Weiss, Nigel

    2001-06-01

    Nigel Weiss recounts his Presidential Address 2001, given to the RAS A&G Ordinary Meeting on 9 February 2001. Recent high-resolution observations, from the ground and from space, have revealed the fine structure of magnetic features at the surface of the Sun. At the same time, advances in computing power have at last made it possible to develop models of turbulent magnetoconvection that can be related to these observations. The key features of flux emergence and annihilation, as observed by the MDI experiment on SOHO, are reproduced in kinematic calculations, while three-dimensional numerical experiments reveal the dynamical processes that are involved. The pattern of convection depends on the strength of the magnetic field: as the mean field decreases, slender rising plumes give way to a regime where magnetic flux is separated from the motion and then to one where locally intense magnetic fields nestle between broad and vigorously convecting plumes. Moreover, turbulent convection is itself able to act as a small-scale dynamo, generating disordered fields near the solar surface.

  14. 76 FR 21783 - Submission for Review: Presidential Management Fellows (PMF) Nomination Form, OPM 1300, 3206-0082

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-18

    ... Form 1300, Presidential Management Fellows (PMF) Nomination Form, is used by accredited colleges and... OFFICE OF PERSONNEL MANAGEMENT Submission for Review: Presidential Management Fellows (PMF) Nomination Form, OPM 1300, 3206-0082 AGENCY: U.S. Office of Personnel Management. ACTION: 60-Day notice and...

  15. Presidential Green Chemistry Challenge: 2009 Designing Greener Chemicals Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2009 award winners, Procter & Gamble Co. (P&G) and Cook Composites and Polymers Co. (CCP), developed Chempol MPS resins and Sefose sucrose esters to enable high-performance low-VOC alkyd paints.

  16. Presidential Green Chemistry Challenge: 2012 Greener Synthetic Pathways Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2012 award winner, Codexis and Professor Yi Tang, developed a synthesis for the high cholesterol drug, simvastatin, using an engineered acyltransferase enzyme and a low-cost acyl donor as a feedstock.

  17. Presidential Green Chemistry Challenge: 1996 Greener Reaction Conditions Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 1996 award winner, Dow Chemical Company, developed a process to manufacture polystyrene foam sheet packaging that uses carbon dioxide (CO2) as a blowing agent, eliminating CFC-12 and HCFC-22.

  18. Older Voters and the 1992 Presidential Election.

    ERIC Educational Resources Information Center

    Binstock, Robert H.

    1992-01-01

    Examines what is known about one element of the politics of aging--the voting behavior of older persons in recent presidential elections--and suggests areas of research on the 1992 election that may tell something about how far, and how soon, proponents of generational equity will be able to move toward dismantling policies that benefit older…

  19. Teachers' Controversial Issue Decisions Related to Race, Gender, and Religion during the 2008 Presidential Election

    ERIC Educational Resources Information Center

    Journell, Wayne

    2011-01-01

    Using the 2008 Presidential Election as a case of curricular controversy, the author describes how six high school government teachers responded to the racial, gender, and religious diversity included on the presidential tickets of the two major political parties. Teachers had to decide whether the issue of Americans challenging the tradition of…

  20. Presidential Green Chemistry Challenge: 2016 Greener Reaction Conditions Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2016 award winner, Dow Agrosciences LLC, developed Instinct®, a technology that reduces fertilizer nitrate leaching to ground and surface waters and atmospheric nitrous oxide emissions. More corn and reduces CO2.

  1. Presidential Compensation in Higher Education: Policies & Best Practices.

    ERIC Educational Resources Information Center

    Atwell, Robert H.; Wellman, Jane V.

    2000-01-01

    This book is designed to help leaders of higher education institutions set and negotiate compensation for academic presidents. Its central aim is to strengthen governing board decisions regarding presidential compensation, though it also focuses on other highly compensated institutional officers. The findings are based on interviews with…

  2. 36 CFR 1281.8 - What information must be provided to NARA for its report to Congress on a new Presidential...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... provided to NARA for its report to Congress on a new Presidential library facility? 1281.8 Section 1281.8... PRESIDENTIAL LIBRARY FACILITIES § 1281.8 What information must be provided to NARA for its report to Congress on a new Presidential library facility? (a) NARA must submit a report to Congress on a proposed new...

  3. 36 CFR 1281.8 - What information must be provided to NARA for its report to Congress on a new Presidential...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... provided to NARA for its report to Congress on a new Presidential library facility? 1281.8 Section 1281.8... PRESIDENTIAL LIBRARY FACILITIES § 1281.8 What information must be provided to NARA for its report to Congress on a new Presidential library facility? (a) NARA must submit a report to Congress on a proposed new...

  4. 36 CFR 1281.8 - What information must be provided to NARA for its report to Congress on a new Presidential...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... provided to NARA for its report to Congress on a new Presidential library facility? 1281.8 Section 1281.8... PRESIDENTIAL LIBRARY FACILITIES § 1281.8 What information must be provided to NARA for its report to Congress on a new Presidential library facility? (a) NARA must submit a report to Congress on a proposed new...

  5. 36 CFR 1281.8 - What information must be provided to NARA for its report to Congress on a new Presidential...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... provided to NARA for its report to Congress on a new Presidential library facility? 1281.8 Section 1281.8... PRESIDENTIAL LIBRARY FACILITIES § 1281.8 What information must be provided to NARA for its report to Congress on a new Presidential library facility? (a) NARA must submit a report to Congress on a proposed new...

  6. Context-invariant quasi hidden variable (qHV) modelling of all joint von Neumann measurements for an arbitrary Hilbert space

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Loubenets, Elena R.

    We prove the existence for each Hilbert space of the two new quasi hidden variable (qHV) models, statistically noncontextual and context-invariant, reproducing all the von Neumann joint probabilities via non-negative values of real-valued measures and all the quantum product expectations—via the qHV (classical-like) average of the product of the corresponding random variables. In a context-invariant model, a quantum observable X can be represented by a variety of random variables satisfying the functional condition required in quantum foundations but each of these random variables equivalently models X under all joint von Neumann measurements, regardless of their contexts. The proved existence ofmore » this model negates the general opinion that, in terms of random variables, the Hilbert space description of all the joint von Neumann measurements for dimH≥3 can be reproduced only contextually. The existence of a statistically noncontextual qHV model, in particular, implies that every N-partite quantum state admits a local quasi hidden variable model introduced in Loubenets [J. Math. Phys. 53, 022201 (2012)]. The new results of the present paper point also to the generality of the quasi-classical probability model proposed in Loubenets [J. Phys. A: Math. Theor. 45, 185306 (2012)].« less

  7. Temporal development of near-native functional properties and correlations with qMRI in self-assembling fibrocartilage treated with exogenous lysyl oxidase homolog 2.

    PubMed

    Hadidi, Pasha; Cissell, Derek D; Hu, Jerry C; Athanasiou, Kyriacos A

    2017-12-01

    relationship between qMRI metrics and the pyridinoline cross-link content of an engineered collagenous tissue. Copyright © 2017 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

  8. Presidential Green Chemistry Challenge: 2013 Greener Synthetic Pathways Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2013 award winner, Life Technologies, developed a one-pot synthesis for polymerase chain reaction (PCR), which is a much more efficient process that prevents about 1.5 million pounds of hazardous waste a year.

  9. Replica of the Presidential Medal of Freedom Award

    NASA Image and Video Library

    1970-04-18

    S70-35562 (April 1970) --- A photographic replica of the Presidential Medal of Freedom Award which President Richard M. Nixon presented to the Apollo 13 Missions Operations Team (MOT). The presentation was made by the Chief Executive during a visit to the Manned Spacecraft Center (MSC) in April 1970.

  10. Rhetorical Legitimacy, and the Presidential Debates.

    ERIC Educational Resources Information Center

    Lucaites, John Louis

    1989-01-01

    Explores the negative popular reaction to the 1988 Presidential Debates. Examines how these events function as ritualistic enactments of the , thus providing a rhetorical legitimacy for the electoral process in a system dedicated to . Suggests how the 1988 debates failed to satisfy that function. (MM)

  11. The Jackson Presidential Campaign: Setting the Public Agenda.

    ERIC Educational Resources Information Center

    Dates, Jannette Lake; Gandy, Oscar, Jr.

    Print news media coverage of Jesse Jackson's 1984 presidential campaign was analyzed to determine whether publishers followed their roles as liberal, moderate, or conservative publications in their coverage. It was hypothesized that print media coverage would be similar across publications regardless of editorial slant, because of the dominance of…

  12. National space transportation studies

    NASA Technical Reports Server (NTRS)

    Durocher, Cort L.; Irby, Thomas M.; Jenkins, James C.; Gorski, Raymond J.

    1986-01-01

    This paper describes the government and industry activities and findings in response to a Presidential directive to study second-generation space transportation systems. Topics discussed include study purpose, mission needs, architecture development, system concepts, and technology recommendations. Interim study findings will also be presented. The study is being jointly managed by DOD and NASA and equally funded by DOD, NASA, and the Strategic Defense Initiative Organization.

  13. Model-free and analytical EAP reconstruction via spherical polar Fourier diffusion MRI.

    PubMed

    Cheng, Jian; Ghosh, Aurobrata; Jiang, Tianzi; Deriche, Rachid

    2010-01-01

    How to estimate the diffusion Ensemble Average Propagator (EAP) from the DWI signals in q-space is an open problem in diffusion MRI field. Many methods were proposed to estimate the Orientation Distribution Function (ODF) that is used to describe the fiber direction. However, ODF is just one of the features of the EAP. Compared with ODF, EAP has the full information about the diffusion process which reflects the complex tissue micro-structure. Diffusion Orientation Transform (DOT) and Diffusion Spectrum Imaging (DSI) are two important methods to estimate the EAP from the signal. However, DOT is based on mono-exponential assumption and DSI needs a lot of samplings and very large b values. In this paper, we propose Spherical Polar Fourier Imaging (SPFI), a novel model-free fast robust analytical EAP reconstruction method, which almost does not need any assumption of data and does not need too many samplings. SPFI naturally combines the DWI signals with different b-values. It is an analytical linear transformation from the q-space signal to the EAP profile represented by Spherical Harmonics (SH). We validated the proposed methods in synthetic data, phantom data and real data. It works well in all experiments, especially for the data with low SNR, low anisotropy, and non-exponential decay.

  14. Quantitative Chemical Exchange Saturation Transfer MRI of Intervertebral Disc in a Porcine Model

    PubMed Central

    Zhou, Zhengwei; Bez, Maxim; Tawackoli, Wafa; Giaconi, Joseph; Sheyn, Dmitriy; de Mel, Sandra; Maya, Marcel M.; Pressman, Barry D.; Gazit, Zulma; Pelled, Gadi; Gazit, Dan; Li, Debiao

    2017-01-01

    Purpose Previous studies have associated low pH in interver-tebral discs (IVDs) with discogenic back pain. The purpose of this study was to determine whether quantitative CEST (qCEST) MRI can be used to detect pH changes in IVDs in vivo. Methods The exchange rate ksw between glycosaminoglycan (GAG) protons and water protons was determined from qCEST analysis. Its dependence on pH value was investigated in GAG phantoms with varying pH and concentrations. The relationship between ksw and pH was studied further in vivo in a porcine model on a 3T MR scanner and validated using a pH meter. Sodium lactate was injected into the IVDs to induce various pH values within the discs ranging from 5 to 7. Results Phantom and animal results revealed that ksw measured using qCEST MRI is highly correlated with pH level. In the animal studies, the relationship can be described as ksw =9.2 × 106 × 10−pH + 196.9, R2 = 0.7883. Conclusion The exchange rate between GAG and water protons determined from qCEST MRI is closely correlated with pH value. This technique has the potential to noninvasively measure pH in the IVDs of patients with discogenic pain. PMID:27670140

  15. Get Real: Teaching about the Presidential Election

    ERIC Educational Resources Information Center

    McGuire, Margit; Waldman, John

    2008-01-01

    A paramount duty of education is to prepare young people for their role as citizens in a democratic society. Voting is one of the important responsibilities of a citizen but statistics indicate that young people often don't vote and don't believe they have a stake in the outcome of the presidential election. Storypath is a teaching strategy that…

  16. 78 FR 22765 - Presidential Determination on Eligibility of the Federal Republic of Somalia To Receive Defense...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-16

    ... #0; #0; #0; Presidential Documents #0; #0; #0;#0;Federal Register / Vol. 78 , No. 73 / Tuesday... April 8, 2013 Presidential Determination on Eligibility of the Federal Republic of Somalia To Receive... me by the Constitution and the laws of the United States, including section 503(a) of the Foreign...

  17. 77 FR 3369 - Presidential Determination on the Eligibility of South Sudan To Receive Defense Articles and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-24

    ... #0; #0; #0; Presidential Documents #0; #0; #0;#0;Federal Register / Vol. 77, No. 15 / Tuesday... the Constitution and the laws of the United States, including section 503(a) of the Foreign Assistance... Federal Register. (Presidential Sig.) THE WHITE HOUSE, Washington, January 6, 2012 [FR Doc. 2012-1545...

  18. Presidential Green Chemistry Challenge: 2015 Greener Synthetic Pathways Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2015 award winner, LanzaTech Inc. developed a method to utilize gas streams with a range of CO and H2 compositions to produce fuels such as ethanol and chemicals at high selectivities and yields

  19. Q&A: The space poet

    NASA Astrophysics Data System (ADS)

    Hoffman, Jascha

    2011-11-01

    Tracy K. Smith has her head in the stars. Thanks to her late father's job as an engineer on the Hubble Space Telescope, the US poet gathers inspiration from astrophysics and cosmology. Published this year, her third collection, Life on Mars, explores the future of human life, the great beyond and her father's death. As she prepares for a poetry reading at the Space Telescope Science Institute in Baltimore, Maryland, Smith talks about the limits of space and time.

  20. Velopharyngeal Anatomy in 22q11.2 Deletion Syndrome: A Three-Dimensional Cephalometric Analysis

    PubMed Central

    Ruotolo, Rachel A.; Veitia, Nestor A.; Corbin, Aaron; McDonough, Joseph; Solot, Cynthia B.; McDonald-McGinn, Donna; Zackai, Elaine H.; Emanuel, Beverly S.; Cnaan, Avital; LaRossa, Don; Arens, Raanan; Kirschner, Richard E.

    2010-01-01

    Objective 22q11.2 deletion syndrome is the most common genetic cause of velopharyngeal dysfunction (VPD). Magnetic resonance imaging (MRI) is a promising method for noninvasive, three-dimensional (3D) assessment of velopharyngeal (VP) anatomy. The purpose of this study was to assess VP structure in patients with 22q11.2 deletion syndrome by using 3D MRI analysis. Design This was a retrospective analysis of magnetic resonance images obtained in patients with VPD associated with a 22q11.2 deletion compared with a normal control group. Setting This study was conducted at The Children’s Hospital of Philadelphia, a pediatric tertiary care center. Patients, Participants The study group consisted of 5 children between the ages of 2.9 and 7.9 years, with 22q11.2 deletion syndrome confirmed by fluorescence in situ hybridization analysis. All had VPD confirmed by nasendoscopy or videofluoroscopy. The control population consisted of 123 unaffected patients who underwent MRI for reasons other than VP assessment. Interventions Axial and sagittal T1- and T2-weighted magnetic resonance images with 3-mm slice thickness were obtained from the orbit to the larynx in all patients by using a 1.5T Siemens Visions system. Outcome Measures Linear, angular, and volumetric measurements of VP structures were obtained from the magnetic resonance images with VIDA image- processing software. Results The study group demonstrated greater anterior and posterior cranial base and atlanto-dental angles. They also demonstrated greater pharyngeal cavity volume and width and lesser tonsillar and adenoid volumes. Conclusion Patients with a 22q11.2 deletion demonstrate significant alterations in VP anatomy that may contribute to VPD. PMID:16854203

  1. TH-E-17A-04: Geometric Validation of K-Space Self-Gated 4D-MRI Vs. 4D-CT Using A Respiratory Motion Phantom

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yue, Y; Fan, Z; Yang, W

    Purpose: 4D-CT is often limited by motion artifacts, low temporal resolution, and poor phase-based target definition. We recently developed a novel k-space self-gated 4D-MRI technique with high spatial and temporal resolution. The goal here is to geometrically validate 4D-MRI using a MRI-CT compatible respiratory motion phantom and comparison to 4D-CT. Methods: 4D-MRI was acquired using 3T spoiled gradient echo-based 3D projection sequences. Respiratory phases were resolved using self-gated k-space lines as the motion surrogate. Images were reconstructed into 10 temporal bins with 1.56×1.56×1.56mm3. A MRI-CT compatible phantom was designed with a 23mm diameter ball target filled with highconcentration gadolinium(Gd) gelmore » embedded in a 35×40×63mm3 plastic box stabilized with low-concentration Gd gel. The whole phantom was driven by an air pump. Human respiratory motion was mimicked using the controller from a commercial dynamic phantom (RSD). Four breathing settings (rates/depths: 10s/20mm, 6s/15mm, 4s/10mm, 3s/7mm) were scanned with 4D-MRI and 4D-CT (slice thickness 1.25mm). Motion ground-truth was obtained from input signals and real-time video recordings. Reconstructed images were imported into Eclipse(Varian) for target contouring. Volumes and target positions were compared with ground-truth. Initial human study was investigated on a liver patient. Results: 4D-MRI and 4D-CT scans for the different breathing cycles were reconstructed with 10 phases. Target volume in each phase was measured for both 4D-CT and 4D-MRI. Volume percentage difference for the 6.37ml target ranged from 6.67±5.33 to 11.63±5.57 for 4D-CT and from 1.47±0.52 to 2.12±1.60 for 4D-MRI. The Mann-Whitney U-test shows the 4D-MRI is significantly superior to 4D-CT (p=0.021) for phase-based target definition. Centroid motion error ranges were 1.35–1.25mm (4D-CT), and 0.31–0.12mm (4D-MRI). Conclusion: The k-space self-gated 4D-MRI we recently developed can accurately determine

  2. Presidential Green Chemistry Challenge: 2012 Academic Award (Waymouth and Hedrick)

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2012 award winners, Professor Robert M. Waymouth and Dr. James L. Hedrick, developed a broad class of highly active, environmentally benign, metal-free catalysts for synthesizing plastics.

  3. 5 CFR 317.703 - Guaranteed reinstatement: Presidential appointees.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... appointee who was appointed by the President to a civil service position outside the SES without a break in service, and who left the Presidential appointment for reasons other than misconduct, neglect of duty, or... break in service between the two appointments, the individual continues to be entitled to be reinstated...

  4. Presidential Rhetoric and the Purpose of American Education

    ERIC Educational Resources Information Center

    Carpenter II, Dick M.

    2005-01-01

    This study examines how U.S. presidents have defined the purpose of education. Presidential rhetoric about education in inaugural and State of the Union speeches was collected and examined. Throughout history, two purposes of education have gained the most attention?civic responsibility and economic efficiency?with emphasis shifting from civic…

  5. Presidential Green Chemistry Challenge: 1998 Academic Award (Draths and Frost)

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 1998 award winners, Dr. Karen M. Draths and Professor John W. Frost, used benign, genetically engineered microbes and sugars (instead of benzene) to synthesize adipic acid and catechol.

  6. Towards a politics of disaster response: presidential disaster instructions in China, 1998-2012.

    PubMed

    Tao, Peng; Chen, Chunliang

    2018-04-01

    China's disaster management system contains no law-based presidential disaster declarations; however, the national leader's instructions (pishi in Chinese) play a similar role to disaster declarations, which increase the intensity of disaster relief. This raises the question of what affects presidential disaster instructions within an authoritarian regime. This research shows that China's disaster politics depend on a crisis threshold system for operation and that the public and social features of disasters are at the core of this system. China's political cycle has no significant impact on disaster politics. A change in the emergency management system has a significant bearing on presidential disaster instructions, reflecting the strong influence of the concept of rule of law and benefiting the sustainable development of the emergency management system. In terms of disaster politics research, unlocking the black box of China's disaster politics and increasing the number of comparative political studies will benefit the development of empirical and theoretical study. © 2018 The Author(s). Disasters © Overseas Development Institute, 2018.

  7. Presidential Transitions: It's Not Just the Position, It's the Transition. ACE/Praeger Series on Higher Education

    ERIC Educational Resources Information Center

    Sanaghan, Patrick H.; Goldstein, Larry; Gaval, Kathleen D.

    2007-01-01

    A presidential transition has a major impact on the life of an institution. Hundreds of presidential transitions take place annually, and when they are not amicable and carefully orchestrated, they can scar both the institution and the president. This book is designed to provide assistance to presidents, trustees, faculty, and other important…

  8. Presidential Leadership: Moral Leadership in the New Millennium.

    ERIC Educational Resources Information Center

    Corrigan, Robert A.

    2002-01-01

    Discusses the opportunities college and university presidential leaders have to contribute the resources of their institutions to public service. Leaders in higher education must keep the balance between free speech and civility and maintain the small world that is the university as a model of what the greater world should be. (SLD)

  9. Quantitative chemical exchange saturation transfer (qCEST) MRI - omega plot analysis of RF-spillover-corrected inverse CEST ratio asymmetry for simultaneous determination of labile proton ratio and exchange rate.

    PubMed

    Wu, Renhua; Xiao, Gang; Zhou, Iris Yuwen; Ran, Chongzhao; Sun, Phillip Zhe

    2015-03-01

    Chemical exchange saturation transfer (CEST) MRI is sensitive to labile proton concentration and exchange rate, thus allowing measurement of dilute CEST agent and microenvironmental properties. However, CEST measurement depends not only on the CEST agent properties but also on the experimental conditions. Quantitative CEST (qCEST) analysis has been proposed to address the limitation of the commonly used simplistic CEST-weighted calculation. Recent research has shown that the concomitant direct RF saturation (spillover) effect can be corrected using an inverse CEST ratio calculation. We postulated that a simplified qCEST analysis is feasible with omega plot analysis of the inverse CEST asymmetry calculation. Specifically, simulations showed that the numerically derived labile proton ratio and exchange rate were in good agreement with input values. In addition, the qCEST analysis was confirmed experimentally in a phantom with concurrent variation in CEST agent concentration and pH. Also, we demonstrated that the derived labile proton ratio increased linearly with creatine concentration (P < 0.01) while the pH-dependent exchange rate followed a dominantly base-catalyzed exchange relationship (P < 0.01). In summary, our study verified that a simplified qCEST analysis can simultaneously determine labile proton ratio and exchange rate in a relatively complex in vitro CEST system. Copyright © 2015 John Wiley & Sons, Ltd.

  10. Anterior pituitary failure (panhypopituitarism) with balanced chromosome translocation 46,XY,t(11;22)(q24;q13).

    PubMed

    Yang, C Y; Chou, C W; Chen, S Y; Cheng, H M

    2001-04-01

    Hypopituitarism is the clinical syndrome that results from failure of the anterior pituitary gland to produce its hormones. Hypopituitarism can result from: (1) intrinsic or primary pituitary disease; (2) intrinsic hypothalamic or secondary pituitary disease; or (3) extrinsic extrasellar or parasellar disease. The etiologies of primary hypopituitarism are miscellaneous. The dominant clinical picture of hypopituitarism in the adult is that of hypogonadism. Reports have associated hypopituitarism with anti-pituitary-antibodies, hereditary syndrome and chromosome defects, but hypopituitarism has rarely been associated with balanced chromosome translocation (11;22)(q24;q13). Here, we describe a case of anterior pituitary failure with balanced chromosome translocation. A 19-year-old Chinese teenager presented with failure of pubertal development and sexual infantilism. On examination, the patient had the classic appearance of hypogonadism. Endocrine studies and three combined pituitary function tests revealed panhypopituitarism. A chromosomal study revealed 46,XY,t(11;22)(q24;q13), a balanced translocation between 11q24 and 22q13. Chest films showed delayed fusion of bilateral humeral head epiphyses and bilateral acromions. Scrotal sonography revealed testes were small bilaterally. Magnetic resonance imaging (MRI) of the sella revealed pituitary dwarfism. The patient received 19 months replacement therapy, including steroids (prednisolone 5 mg each day), L-thyroxine (Eltroxin 100 ug each day), and testosterone enanthate 250 mg every two weeks. His height increased 4 cm with secondary sexual characteristics developed, and muscle power increased.

  11. 36 CFR 1256.80 - How does NARA provide classified access to historical researchers and former Presidential...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Presidential appointees? (a) In accordance with the requirements of section 4.4 of E.O. 12958, as amended, we... request for access. If you seek access to classified Presidential records under section 4.4 of E.O. 12958... information originated by the White House or classified information in the custody of the National Archives...

  12. Measurement tensors in diffusion MRI: generalizing the concept of diffusion encoding.

    PubMed

    Westin, Carl-Fredrik; Szczepankiewicz, Filip; Pasternak, Ofer; Ozarslan, Evren; Topgaard, Daniel; Knutsson, Hans; Nilsson, Markus

    2014-01-01

    In traditional diffusion MRI, short pulsed field gradients (PFG) are used for the diffusion encoding. The standard Stejskal-Tanner sequence uses one single pair of such gradients, known as single-PFG (sPFG). In this work we describe how trajectories in q-space can be used for diffusion encoding. We discuss how such encoding enables the extension of the well-known scalar b-value to a tensor-valued entity we call the diffusion measurement tensor. The new measurements contain information about higher order diffusion propagator covariances not present in sPFG. As an example analysis, we use this new information to estimate a Gaussian distribution over diffusion tensors in each voxel, described by its mean (a diffusion tensor) and its covariance (a 4th order tensor).

  13. 36 CFR § 1281.8 - What information must be provided to NARA for its report to Congress on a new Presidential...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... provided to NARA for its report to Congress on a new Presidential library facility? § 1281.8 Section Â... PRESIDENTIAL LIBRARY FACILITIES § 1281.8 What information must be provided to NARA for its report to Congress on a new Presidential library facility? (a) NARA must submit a report to Congress on a proposed new...

  14. A Value Analysis of the 1980 Presidential Debate.

    ERIC Educational Resources Information Center

    Hochel, Sandra

    Although Democrat Jimmy Carter and Republican Ronald Reagan appealed to many of the same basic American values in the 1980 presidential campaign debate, there were some subtle but major differences in their value appeals. Other than attempting to convince his audience that his policies had been and would be successful and that Reagan's policies…

  15. Analysis of EEG-fMRI data in focal epilepsy based on automated spike classification and Signal Space Projection.

    PubMed

    Liston, Adam D; De Munck, Jan C; Hamandi, Khalid; Laufs, Helmut; Ossenblok, Pauly; Duncan, John S; Lemieux, Louis

    2006-07-01

    Simultaneous acquisition of EEG and fMRI data enables the investigation of the hemodynamic correlates of interictal epileptiform discharges (IEDs) during the resting state in patients with epilepsy. This paper addresses two issues: (1) the semi-automation of IED classification in statistical modelling for fMRI analysis and (2) the improvement of IED detection to increase experimental fMRI efficiency. For patients with multiple IED generators, sensitivity to IED-correlated BOLD signal changes can be improved when the fMRI analysis model distinguishes between IEDs of differing morphology and field. In an attempt to reduce the subjectivity of visual IED classification, we implemented a semi-automated system, based on the spatio-temporal clustering of EEG events. We illustrate the technique's usefulness using EEG-fMRI data from a subject with focal epilepsy in whom 202 IEDs were visually identified and then clustered semi-automatically into four clusters. Each cluster of IEDs was modelled separately for the purpose of fMRI analysis. This revealed IED-correlated BOLD activations in distinct regions corresponding to three different IED categories. In a second step, Signal Space Projection (SSP) was used to project the scalp EEG onto the dipoles corresponding to each IED cluster. This resulted in 123 previously unrecognised IEDs, the inclusion of which, in the General Linear Model (GLM), increased the experimental efficiency as reflected by significant BOLD activations. We have also shown that the detection of extra IEDs is robust in the face of fluctuations in the set of visually detected IEDs. We conclude that automated IED classification can result in more objective fMRI models of IEDs and significantly increased sensitivity.

  16. Fuzzy Q-Learning for Generalization of Reinforcement Learning

    NASA Technical Reports Server (NTRS)

    Berenji, Hamid R.

    1996-01-01

    Fuzzy Q-Learning, introduced earlier by the author, is an extension of Q-Learning into fuzzy environments. GARIC is a methodology for fuzzy reinforcement learning. In this paper, we introduce GARIC-Q, a new method for doing incremental Dynamic Programming using a society of intelligent agents which are controlled at the top level by Fuzzy Q-Learning and at the local level, each agent learns and operates based on GARIC. GARIC-Q improves the speed and applicability of Fuzzy Q-Learning through generalization of input space by using fuzzy rules and bridges the gap between Q-Learning and rule based intelligent systems.

  17. 1 CFR 12.4 - Weekly Compilation of Presidential Documents.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 1 General Provisions 1 2010-01-01 2010-01-01 false Weekly Compilation of Presidential Documents. 12.4 Section 12.4 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER AVAILABILITY OF OFFICE OF THE FEDERAL REGISTER PUBLICATIONS OFFICIAL DISTRIBUTION WITHIN FEDERAL GOVERNMENT § 12.4 Weekly...

  18. A 4-channel 3 Tesla phased array receive coil for awake rhesus monkey fMRI and diffusion MRI experiments.

    PubMed

    Khachaturian, Mark Haig

    2010-01-01

    Awake monkey fMRI and diffusion MRI combined with conventional neuroscience techniques has the potential to study the structural and functional neural network. The majority of monkey fMRI and diffusion MRI experiments are performed with single coils which suffer from severe EPI distortions which limit resolution. By constructing phased array coils for monkey MRI studies, gains in SNR and anatomical accuracy (i.e., reduction of EPI distortions) can be achieved using parallel imaging. The major challenges associated with constructing phased array coils for monkeys are the variation in head size and space constraints. Here, we apply phased array technology to a 4-channel phased array coil capable of improving the resolution and image quality of full brain awake monkey fMRI and diffusion MRI experiments. The phased array coil is that can adapt to different rhesus monkey head sizes (ages 4-8) and fits in the limited space provided by monkey stereotactic equipment and provides SNR gains in primary visual cortex and anatomical accuracy in conjunction with parallel imaging and improves resolution in fMRI experiments by a factor of 2 (1.25 mm to 1.0 mm isotropic) and diffusion MRI experiments by a factor of 4 (1.5 mm to 0.9 mm isotropic).

  19. A 4-channel 3 Tesla phased array receive coil for awake rhesus monkey fMRI and diffusion MRI experiments

    PubMed Central

    Khachaturian, Mark Haig

    2010-01-01

    Awake monkey fMRI and diffusion MRI combined with conventional neuroscience techniques has the potential to study the structural and functional neural network. The majority of monkey fMRI and diffusion MRI experiments are performed with single coils which suffer from severe EPI distortions which limit resolution. By constructing phased array coils for monkey MRI studies, gains in SNR and anatomical accuracy (i.e., reduction of EPI distortions) can be achieved using parallel imaging. The major challenges associated with constructing phased array coils for monkeys are the variation in head size and space constraints. Here, we apply phased array technology to a 4-channel phased array coil capable of improving the resolution and image quality of full brain awake monkey fMRI and diffusion MRI experiments. The phased array coil is that can adapt to different rhesus monkey head sizes (ages 4–8) and fits in the limited space provided by monkey stereotactic equipment and provides SNR gains in primary visual cortex and anatomical accuracy in conjunction with parallel imaging and improves resolution in fMRI experiments by a factor of 2 (1.25 mm to 1.0 mm isotropic) and diffusion MRI experiments by a factor of 4 (1.5 mm to 0.9 mm isotropic). PMID:21243106

  20. Understanding the Primary School Students' Van Hiele Levels of Geometry Thinking in Learning Shapes and Spaces: A Q-Methodology

    ERIC Educational Resources Information Center

    Hock, Tan Tong; Tarmizi, Rohani Ahmad; Yunus, Aida Suraya Md.; Ayub, Ahmad Fauzi

    2015-01-01

    This study was conducted using a new hybrid method of research which combined qualitative and quantitative designs to investigate the viewpoints of primary school students' conceptual understanding in learning geometry from the aspect of shapes and spaces according to van Hiele theory. Q-methodology is used in this research to find out what…

  1. Presidential Spouses: Worth Taking Seriously, and Worth Paying

    ERIC Educational Resources Information Center

    Moser, Kate

    2008-01-01

    Mrs. Deborah J. Cofer is one of many presidential spouses who balk at the thought of being paid for their work--whether because they relish the freedom to take a night off or because they think of it as a natural part of their relationships with their partners. Mrs. Cofer believes that their mission is to enhance students' lives and they do not…

  2. Partial trisomy 12q24.31----qter.

    PubMed Central

    Tajara, E H; Varella-Garcia, M; Gusson, A C

    1985-01-01

    Clinical details of a male child with the karyotype 46,XY,-4,+der(4),t(4;12) (p16;q24.31)mat are reported and compared with those of other known cases of partial trisomy of the distal region of 12q. This condition is apparently associated with mental and psychomotor retardation, widely spaced eyes, flat nasal bridge, low set ears, down-turned mouth, micrognathia, loose skin at the nape, widely spaced nipples, simian creases, clinodactyly, abnormalities of the genitourinary system, alterations in the sacrococcygeal region, and deformities of the lower limbs. In the majority of the reported cases, the break-point was in the 12q24 region and resulted from adjacent 1 segregation of a maternal balanced translocation. Images PMID:3981585

  3. Presidential Inaugurations: Planning for More than Pomp and Circumstance.

    ERIC Educational Resources Information Center

    Viola, Joy Winkie

    This publication covers the fundamentals of planning a college or university presidential inauguration. The guide's 10 chapters are based in part on a survey of colleges and universities that appointed new presidents between January 1990 and January 1992. The first chapter offers five rules for "getting your act together": you should…

  4. 11 CFR 100.152 - Fundraising costs for Presidential candidates.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    .... 100.152 Section 100.152 Federal Elections FEDERAL ELECTION COMMISSION GENERAL SCOPE AND DEFINITIONS (2 U.S.C. 431) Exceptions to Expenditures § 100.152 Fundraising costs for Presidential candidates. (a... exempt fundraising activities under 11 CFR 110.8(c)(2), plus (2) An amount of costs that would otherwise...

  5. Exploiting the wavelet structure in compressed sensing MRI.

    PubMed

    Chen, Chen; Huang, Junzhou

    2014-12-01

    Sparsity has been widely utilized in magnetic resonance imaging (MRI) to reduce k-space sampling. According to structured sparsity theories, fewer measurements are required for tree sparse data than the data only with standard sparsity. Intuitively, more accurate image reconstruction can be achieved with the same number of measurements by exploiting the wavelet tree structure in MRI. A novel algorithm is proposed in this article to reconstruct MR images from undersampled k-space data. In contrast to conventional compressed sensing MRI (CS-MRI) that only relies on the sparsity of MR images in wavelet or gradient domain, we exploit the wavelet tree structure to improve CS-MRI. This tree-based CS-MRI problem is decomposed into three simpler subproblems then each of the subproblems can be efficiently solved by an iterative scheme. Simulations and in vivo experiments demonstrate the significant improvement of the proposed method compared to conventional CS-MRI algorithms, and the feasibleness on MR data compared to existing tree-based imaging algorithms. Copyright © 2014 Elsevier Inc. All rights reserved.

  6. Pericentric inversion of chromosome 11 (p14.3q21) associated with developmental delays, hypopigmented skin lesions and abnormal brain MRI findings - a new case report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zachor, D.A.; Lofton, M.

    1994-09-01

    We report 3 year old male, referred for evaluation of developmental delays. Pregnancy was complicated by oligohydramnios, proteinuria and prematurity. Medical history revealed: bilateral inguinal hernia, small scrotal sac, undescended testes, developmental delays and behavioral problems. The child had: microcephaly, facial dysmorphic features, single palmar creases, hypopigmented skin lesions of variable size, intermittent exotropia and small retracted testes. Neurological examination was normal. Cognitive level was at the average range with mild delay in his adaptive behavior. Expressive language delays and severe articulation disorder were noted, as well as clumsiness, poor control and precision of gross and fine motor skills. Chromosomalmore » analysis of peripheral leukocytes indicated that one of the number 11 chromosomes had undergone a pericentric inversion with breakpoints on the short (p) arm at band p14.3 and the long (q) arm at band q21. An MRI of the brain showed mild delay in myelinization pattern of white matter. Chromosome 11 inversion in other sites was associated with Beckwith-Wiedemann syndrome and several malignancies. To our knowledge this is the first description of inv(11)(p14.3q21) that is associated with microcephaly, dysmorphic features, hypopigmented skin lesions and speech delay. This inversion may disrupt the expression of the involved genes. However, additional cases with the same cytogenetic anomaly are needed to explore the phenotypic significance of this disorder.« less

  7. Campaign Policies, Broadcasters, and the Presidential Election of 1924.

    ERIC Educational Resources Information Center

    Benjamin, Louise M.

    The policies initiated by broadcasters for campaign coverage during the 1924 presidential election influenced the treatment of political candidates on the air and helped set the stage for inclusion of the equal opportunities clause in the Radio Act of 1927. AT&T, RCA, and General Electric formed policies to treat candidates fairly in…

  8. Diverging Life Expectancies and Voting Patterns in the 2016 US Presidential Election

    PubMed Central

    2017-01-01

    Objectives. To assess whether voting patterns in the 2016 US presidential election were correlated with long-run trends in county life expectancy. Methods. I examined county-level voting data from the 2008 and 2016 presidential elections and assessed Donald Trump’s share of the 2016 vote, change in the Republican vote share between 2008 and 2016, and changes in absolute numbers of Democratic and Republican votes. County-level estimates of life expectancy at birth were obtained for 1980 and 2014 from the Institute for Health Metrics and Evaluation. Results. Changes in county life expectancy from 1980 to 2014 were strongly negatively associated with Trump’s vote share, with less support for Trump in counties experiencing greater survival gains. Counties in which life expectancy stagnated or declined saw a 10-percentage-point increase in the Republican vote share between 2008 and 2016. Conclusions. Residents of counties left out from broader life expectancy gains abandoned the Democratic Party in the 2016 presidential election. Since coming to power, the Trump administration has proposed cuts to health insurance for the poor, social programs, health research, and environmental and worker protections, which are key determinants of population health. Health gaps likely will continue to widen without significant public investment in population health. PMID:28817322

  9. Diverging Life Expectancies and Voting Patterns in the 2016 US Presidential Election.

    PubMed

    Bor, Jacob

    2017-10-01

    To assess whether voting patterns in the 2016 US presidential election were correlated with long-run trends in county life expectancy. I examined county-level voting data from the 2008 and 2016 presidential elections and assessed Donald Trump's share of the 2016 vote, change in the Republican vote share between 2008 and 2016, and changes in absolute numbers of Democratic and Republican votes. County-level estimates of life expectancy at birth were obtained for 1980 and 2014 from the Institute for Health Metrics and Evaluation. Changes in county life expectancy from 1980 to 2014 were strongly negatively associated with Trump's vote share, with less support for Trump in counties experiencing greater survival gains. Counties in which life expectancy stagnated or declined saw a 10-percentage-point increase in the Republican vote share between 2008 and 2016. Residents of counties left out from broader life expectancy gains abandoned the Democratic Party in the 2016 presidential election. Since coming to power, the Trump administration has proposed cuts to health insurance for the poor, social programs, health research, and environmental and worker protections, which are key determinants of population health. Health gaps likely will continue to widen without significant public investment in population health.

  10. Dynamic Contrast-Enhanced MRI in the Evaluation of Carotid Space Paraganglioma versus Schwannoma.

    PubMed

    Gaddikeri, Santhosh; Hippe, Daniel S; Anzai, Yoshimi

    2016-11-01

    To describe the potential role of dynamic contrast-enhanced (DCE) MRI in differentiating carotid space (CS) paraganglioma from schwannoma in the head and neck. We retrospectively reviewed records of 126 patients who had undergone DCE-MRI between June 2008 and July 2014 and found six patients with histologically verified benign CS tumors. The images were evaluated for tumor T1 and T2 signal characteristics, flow voids, and enhancement pattern. The dynamic data were analyzed for quantitative parameters using extended Toft's model (K trans , K ep , V e , and V p ) and semiquantitative parameters based on time-intensity curve (area under curve, peak enhancement, wash-in, wash-out, signal-enhancement ratio [SER], and time for maximum enhancement [TME]). Due to the small sample size, groups were compared qualitatively. Patients with CS paraganglioma (P group, n = 2) and schwannoma (S group, n = 4) were included. All tumors were hypointense on T1W imaging, hyperintense on T2W imaging, and show avid enhancement. One patient with paraganglioma had subtle flow voids. The conventional MR images were insufficient to confidently diagnose tumor type. Both paragangliomas had high peak enhancement and SER, and a short TME, while the schwannomas had relatively low peak enhancement and SER with a longer TME. K trans , K ep , and V e were relatively low in the paragangliomas than in the schwannomas. DCE-MRI could potentially be used to assist differentiating paraganglioma from schwannoma, when diagnosis is difficult on the conventional MR imaging sequences. Simple assessment of semiquantitative parameters suffices to provide supportive information. Copyright © 2016 by the American Society of Neuroimaging.

  11. The Ironist and Hypocrite as Presidential Symbols: A Nixon-Kennedy Analog.

    ERIC Educational Resources Information Center

    Kaufer, David S.

    1979-01-01

    Discusses the self-disparaging ironist and the hypocrite as symbols of power in contemporary American politics. Contrasts the presidential images of Richard Nixon and John Kennedy who exemplify, respectively, hypocritical and ironical power-holders. (PD)

  12. SU(p,q) coherent states and a Gaussian de Finetti theorem

    NASA Astrophysics Data System (ADS)

    Leverrier, Anthony

    2018-04-01

    We prove a generalization of the quantum de Finetti theorem when the local space is an infinite-dimensional Fock space. In particular, instead of considering the action of the permutation group on n copies of that space, we consider the action of the unitary group U(n) on the creation operators of the n modes and define a natural generalization of the symmetric subspace as the space of states invariant under unitaries in U(n). Our first result is a complete characterization of this subspace, which turns out to be spanned by a family of generalized coherent states related to the special unitary group SU(p, q) of signature (p, q). More precisely, this construction yields a unitary representation of the noncompact simple real Lie group SU(p, q). We therefore find a dual unitary representation of the pair of groups U(n) and SU(p, q) on an n(p + q)-mode Fock space. The (Gaussian) SU(p, q) coherent states resolve the identity on the symmetric subspace, which implies a Gaussian de Finetti theorem stating that tracing over a few modes of a unitary-invariant state yields a state close to a mixture of Gaussian states. As an application of this de Finetti theorem, we show that the n × n upper-left submatrix of an n × n Haar-invariant unitary matrix is close in total variation distance to a matrix of independent normal variables if n3 = O(m).

  13. The "Daily Oklahoman" and Persuasion in the Early 1980 Presidential Campaign and A Response by Paul D. Harper.

    ERIC Educational Resources Information Center

    Vartabedian, Robert A.; And Others

    1984-01-01

    A content analysis was conducted of 203 editorials from the "Daily Oklahoman" from the first six months of the 1980 presidential campaign. The analysis was based on two assumptions: (1) the tone of the 1980 presidential campaign essentially was set after only six months of official campaigning, and (2) the "Daily Oklahoman"…

  14. The 2012 NCTE Presidential Address: Literacy, Rhetoric, Education, Democracy

    ERIC Educational Resources Information Center

    Gilyard, Keith

    2013-01-01

    This article presents the text of Keith Gilyard's presidential address, delivered at the National Council of Teachers of English (NCTE) Annual Convention in Las Vegas, Nevada, on November 18, 2012. In his address he proposes several core elements that he believes will instrumentally improve the education system in the United States: a rich…

  15. Triply heavy Q Q Q ¯ q ¯ tetraquark states

    NASA Astrophysics Data System (ADS)

    Jiang, Jin-Feng; Chen, Wei; Zhu, Shi-Lin

    2017-11-01

    Within the framework of QCD sum rules, we have investigated the tetraquark states with three heavy quarks. We systematically construct the interpolating currents for the possible c c c ¯ q ¯ , c c b ¯q ¯, b c b ¯q ¯, b b b ¯q ¯ tetraquark states with quantum numbers JP=0+ and JP=1+. Using these interpolating currents, we have calculated the two-point correlation functions and extracted the mass spectra for the above tetraquark states. We also discuss the decay patterns of these tetraquarks, and notice that the c c c ¯q ¯, c c b ¯q ¯, b c b ¯q ¯ may decay quickly with a narrow width due to their mass spectra. The b b b ¯q ¯ tetraquarks are expected to be very narrow resonances since their OZI (Okubo-Zweig-Iizuka)-allowed decay modes are kinematically forbidden. These states may be searched for in the final states with a B meson plus a light meson or photon.

  16. Quantum Bundle Description of Quantum Projective Spaces

    NASA Astrophysics Data System (ADS)

    Ó Buachalla, Réamonn

    2012-12-01

    We realise Heckenberger and Kolb's canonical calculus on quantum projective ( N - 1)-space C q [ C p N-1] as the restriction of a distinguished quotient of the standard bicovariant calculus for the quantum special unitary group C q [ SU N ]. We introduce a calculus on the quantum sphere C q [ S 2 N-1] in the same way. With respect to these choices of calculi, we present C q [ C p N-1] as the base space of two different quantum principal bundles, one with total space C q [ SU N ], and the other with total space C q [ S 2 N-1]. We go on to give C q [ C p N-1] the structure of a quantum framed manifold. More specifically, we describe the module of one-forms of Heckenberger and Kolb's calculus as an associated vector bundle to the principal bundle with total space C q [ SU N ]. Finally, we construct strong connections for both bundles.

  17. A Q-Band Free-Space Characterization of Carbon Nanotube Composites

    PubMed Central

    Hassan, Ahmed M.; Garboczi, Edward J.

    2016-01-01

    We present a free-space measurement technique for non-destructive non-contact electrical and dielectric characterization of nano-carbon composites in the Q-band frequency range of 30 GHz to 50 GHz. The experimental system and error correction model accurately reconstruct the conductivity of composite materials that are either thicker than the wave penetration depth, and therefore exhibit negligible microwave transmission (less than −40 dB), or thinner than the wave penetration depth and, therefore, exhibit significant microwave transmission. This error correction model implements a fixed wave propagation distance between antennas and corrects the complex scattering parameters of the specimen from two references, an air slab having geometrical propagation length equal to that of the specimen under test, and a metallic conductor, such as an aluminum plate. Experimental results were validated by reconstructing the relative dielectric permittivity of known dielectric materials and then used to determine the conductivity of nano-carbon composite laminates. This error correction model can simplify routine characterization of thin conducting laminates to just one measurement of scattering parameters, making the method attractive for research, development, and for quality control in the manufacturing environment. PMID:28057959

  18. BFV-BRST analysis of the classical and quantum q-deformations of the sl(2) algebra

    NASA Astrophysics Data System (ADS)

    Dayi, O. F.

    1994-01-01

    BFV--BRST charge for q-deformed algebras is not unique. Different constructions of it in the classical as well as in the quantum phase space for the $q$-deformed algebra sl_q(2) are discussed. Moreover, deformation of the phase space without deforming the generators of sl(2) is considered. $\\hbar$-q-deformation of the phase space is shown to yield the Witten's second deformation. To study the BFV--BRST cohomology problem when both the quantum phase space and the group are deformed, a two parameter deformation of sl(2) is proposed, and its BFV-BRST charge is given.

  19. 5 CFR 315.708 - Conversion based on service as a Fellow or Senior Fellow in the Presidential Management Fellows...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... or Senior Fellow in the Presidential Management Fellows Program. 315.708 Section 315.708... Conversion based on service as a Fellow or Senior Fellow in the Presidential Management Fellows Program. (a... Senior Fellow to a full-time, permanent position in the competitive service without further competition...

  20. 78 FR 73582 - Presidential Permit for Kinder Morgan Cochin, LLC

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-06

    ... conditions: Article 1. (1) The United States facilities herein described, and all aspects of their operation... Presidential Permit (the ``Application''). Article 2. The standards for, and the manner of, the operation and... their official duties. Article 3. The permittee shall comply with all applicable federal, state, and...

  1. 15 CFR 2008.17 - Historical researchers and former Presidential appointees.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 15 Commerce and Foreign Trade 3 2013-01-01 2013-01-01 false Historical researchers and former Presidential appointees. 2008.17 Section 2008.17 Commerce and Foreign Trade Regulations Relating to Foreign Trade Agreements OFFICE OF THE UNITED STATES TRADE REPRESENTATIVE REGULATIONS TO IMPLEMENT E.O. 12065...

  2. 15 CFR 2008.17 - Historical researchers and former Presidential appointees.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 15 Commerce and Foreign Trade 3 2014-01-01 2014-01-01 false Historical researchers and former Presidential appointees. 2008.17 Section 2008.17 Commerce and Foreign Trade Regulations Relating to Foreign Trade Agreements OFFICE OF THE UNITED STATES TRADE REPRESENTATIVE REGULATIONS TO IMPLEMENT E.O. 12065...

  3. 15 CFR 2008.17 - Historical researchers and former Presidential appointees.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 15 Commerce and Foreign Trade 3 2011-01-01 2011-01-01 false Historical researchers and former Presidential appointees. 2008.17 Section 2008.17 Commerce and Foreign Trade Regulations Relating to Foreign Trade Agreements OFFICE OF THE UNITED STATES TRADE REPRESENTATIVE REGULATIONS TO IMPLEMENT E.O. 12065...

  4. 15 CFR 2008.17 - Historical researchers and former Presidential appointees.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 15 Commerce and Foreign Trade 3 2012-01-01 2012-01-01 false Historical researchers and former Presidential appointees. 2008.17 Section 2008.17 Commerce and Foreign Trade Regulations Relating to Foreign Trade Agreements OFFICE OF THE UNITED STATES TRADE REPRESENTATIVE REGULATIONS TO IMPLEMENT E.O. 12065...

  5. 15 CFR 2008.17 - Historical researchers and former Presidential appointees.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Historical researchers and former Presidential appointees. 2008.17 Section 2008.17 Commerce and Foreign Trade Regulations Relating to Foreign Trade Agreements OFFICE OF THE UNITED STATES TRADE REPRESENTATIVE REGULATIONS TO IMPLEMENT E.O. 12065...

  6. Challenges in an Aging Society: Presidential Address to APPAM

    ERIC Educational Resources Information Center

    Swartz, Katherine

    2010-01-01

    The United States is at a critical crossroads in its history right now. The public policy problems that the people are facing are complex and interrelated, and the demographic changes that are about to significantly change their country are not well understood by large numbers of people. In this presidential address to the Association for Public…

  7. Foreign Policy News in the 1980 Presidential Election Campaign.

    ERIC Educational Resources Information Center

    Stovall, James Glen

    A survey was conducted to determine the extent and content of newspaper coverage of foreign policy issues in the 1980 United States presidential campaign. Fifty daily newspapers from every region of the country were selected randomly based on circulation. A list of 757 news events was divided into party and nonparty events, and the party events…

  8. A first-digit anomaly in the 2009 Iranian presidential election

    NASA Astrophysics Data System (ADS)

    Roukema, Boudewijn F.

    2014-01-01

    A local bootstrap method is proposed for the analysis of electoral vote-count first-digit frequencies, complementing the Benford's Law limit. The method is calibrated on five presidential-election first rounds (2002-2006) and applied to the 2009 Iranian presidential-election first round. Candidate K has a highly significant (p < 0.15%) excess of vote counts starting with the digit 7. This leads to other anomalies, two of which are individually significant at p˜ 0.1%, and one at p sim 1%. Independently, Iranian pre-election opinion polls significantly reject the official results unless the five polls favouring candidate A are considered alone. If the latter represent normalised data and a linear, least-squares, equal-weighted fit is used, then either candidates R and K suffered a sudden, dramatic (70%pm 15%) loss of electoral support just prior to the election, or the official results are rejected (p ˜ 0.01%).

  9. Presidential Green Chemistry Challenge: 2015 Specific Environmental Benefit: Climate Change Award

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2015 award winner, Algenol, blue-green algae to produce ethanol and other fuels, uses CO2 from air or industrial emitters, reduces the carbon footprint, costs and water usage, no reliance on food crops

  10. Lipschitz and Besov spaces in quantum calculus

    NASA Astrophysics Data System (ADS)

    Nemri, Akram; Selmi, Belgacem

    2016-08-01

    The purpose of this paper is to investigate the harmonic analysis on the time scale 𝕋q, q ∈ (0, 1) to introduce q-weighted Besov spaces subspaces of Lp(𝕋 q) generalizing the classical one. Further, using an example of q-weighted wα,β(.; q) which is introduced and studied. We give a new characterization of the q-Besov space using q-Poisson kernel and the g1 Littlewood-Paley operator.

  11. Presidential Green Chemistry Challenge: 2005 Greener Synthetic Pathways Award (Merck & Co., Inc.)

    EPA Pesticide Factsheets

    Presidential Green Chemistry Challenge 2005 award winner, Merck, designed an atom-economical, energy- and water-saving, convergent synthesis for aprepitant, the active ingredient in Emend, a drug for nausea and vomiting.

  12. Activation pattern of ACE2/Ang-(1-7) and ACE/Ang II pathway in course of heart failure assessed by multiparametric MRI in vivo in Tgαq*44 mice.

    PubMed

    Tyrankiewicz, Urszula; Olkowicz, Mariola; Skórka, Tomasz; Jablonska, Magdalena; Orzylowska, Anna; Bar, Anna; Gonet, Michal; Berkowicz, Piotr; Jasinski, Krzysztof; Zoladz, Jerzy A; Smolenski, Ryszard T; Chlopicki, Stefan

    2018-01-01

    Here, we analyzed systemic (plasma) and local (heart/aorta) changes in ACE/ACE-2 balance in Tgαq*44 mice in course of heart failure (HF). Tgαq*44 mice with cardiomyocyte-specific Gαq overexpression and late onset of HF were analyzed at different age for angiotensin pattern in plasma, heart, and aorta using liquid chromatography/mass spectrometry, for progression of HF by in vivo magnetic resonance imaging under isoflurane anesthesia, and for physical activity by voluntary wheel running. Six-month-old Tgαq*44 mice displayed decreased ventricle radial strains and impaired left atrial function. At 8-10 mo, Tgαq*44 mice showed impaired systolic performance and reduced voluntary wheel running but exhibited preserved inotropic reserve. At 12 mo, Tgαq*44 mice demonstrated a severe impairment of basal cardiac performance and modestly compromised inotropic reserve with reduced voluntary wheel running. Angiotensin analysis in plasma revealed an increase in concentration of angiotensin-(1-7) in 6- to 10-mo-old Tgαq*44 mice. However, in 12- to 14-mo-old Tgαq*44 mice, increased angiotensin II was noted with a concomitant increase in Ang III, Ang IV, angiotensin A, and angiotensin-(1-10). The pattern of changes in the heart and aorta was also compatible with activation of ACE2, followed by activation of the ACE pathway. In conclusion, mice with cardiomyocyte Gαq protein overexpression develop HF that is associated with activation of the systemic and the local ACE/Ang II pathway. However, it is counterbalanced by a prominent ACE2/Ang-(1-7) activation, possibly allowing to delay decompensation. NEW & NOTEWORTHY Changes in ACE/ACE-2 balance were analyzed based on measurements of a panel of nine angiotensins in plasma, heart, and aorta of Tgαq*44 mice in relation to progression of heart failure (HF) characterized by multiparametric MRI and exercise performance. The early stage of HF was associated with upregulation of the ACE2/angiotensin-(1-7) pathway, whereas the end

  13. Unique double de novo structural rearrangements for chromosome 11 with 46,XX,del(11)(q13q23)/46,XX,inv dup(11)(q13q23) in an infant with minor congenital abnormalities and delayed development

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tharapel, A.T.; Zhao, J.; Smith, M.E.

    1994-09-01

    Reported here is a patient with two most unusual structural rearrangements, both involving chromosome 11. The first cell line showed an interstitial deletion of a chromosome 11 with a 46,XX,del(11)(q13q23) chromosome complement. In the second cell line, one of the chromosome 11s had a duplication for the exact region, (11)(q13q23), that was deleted in the first cell line. This duplication also appeared to be inverted with karyotype 46,XX,inv dup(11)(q13q23). Interestingly, chromosome analysis did not reveal a normal cell line and the two abnormal cell lines were present in a 1:1 ratio. Parental chromosome analyses showed normal karyotypes. The patient wasmore » referred for genetic evaluation because of developmental delay. Minor congenital anomalies presented on physical examination included: weight and height at or below the 5th percentile, microcephaly, downward slanting palpebral fissures, severe clinodactyly of one toe, bilateral short fifth fingers and a broad based gait. Results of the MRI and urine metabolic screen were normal. Two hypotheses are advanced to explain the origin of the abnormality. It is most likely that the abnormality arose as a postzygotic event at the very early zygotic division. During the first DNA synthesis after fertilization and before the zygotic division, DNA synthesis errors could result in two chromatids, one with a deletion and the other with a duplication. It is also possible that after the DNA synthesis prior to the first cell division, the chromatids of the same chromosome 11 for unknown reasons were involved in uneven double somatic crossing over events resulting in deleted and duplicated chromatids, respectively. The 1:1 cell ratio found in the patient and the apparent non-existence of a normal cell line further suggest that the origin of the abnormality was post-zygotic.« less

  14. Effectiveness of a Rapid Lumbar Spine MRI Protocol Using 3D T2-Weighted SPACE Imaging Versus a Standard Protocol for Evaluation of Degenerative Changes of the Lumbar Spine.

    PubMed

    Sayah, Anousheh; Jay, Ann K; Toaff, Jacob S; Makariou, Erini V; Berkowitz, Frank

    2016-09-01

    Reducing lumbar spine MRI scanning time while retaining diagnostic accuracy can benefit patients and reduce health care costs. This study compares the effectiveness of a rapid lumbar MRI protocol using 3D T2-weighted sampling perfection with application-optimized contrast with different flip-angle evolutions (SPACE) sequences with a standard MRI protocol for evaluation of lumbar spondylosis. Two hundred fifty consecutive unenhanced lumbar MRI examinations performed at 1.5 T were retrospectively reviewed. Full, rapid, and complete versions of each examination were interpreted for spondylotic changes at each lumbar level, including herniations and neural compromise. The full examination consisted of sagittal T1-weighted, T2-weighted turbo spin-echo (TSE), and STIR sequences; and axial T1- and T2-weighted TSE sequences (time, 18 minutes 40 seconds). The rapid examination consisted of sagittal T1- and T2-weighted SPACE sequences, with axial SPACE reformations (time, 8 minutes 46 seconds). The complete examination consisted of the full examination plus the T2-weighted SPACE sequence. Sensitivities and specificities of the full and rapid examinations were calculated using the complete study as the reference standard. The rapid and full studies had sensitivities of 76.0% and 69.3%, with specificities of 97.2% and 97.9%, respectively, for all degenerative processes. Rapid and full sensitivities were 68.7% and 66.3% for disk herniation, 85.2% and 81.5% for canal compromise, 82.9% and 69.1% for lateral recess compromise, and 76.9% and 69.7% for foraminal compromise, respectively. Isotropic SPACE T2-weighted imaging provides high-quality imaging of lumbar spondylosis, with multiplanar reformatting capability. Our SPACE-based rapid protocol had sensitivities and specificities for herniations and neural compromise comparable to those of the protocol without SPACE. This protocol fits within a 15-minute slot, potentially reducing costs and discomfort for a large subgroup of

  15. Who Will Win?: Predicting the Presidential Election Using Linear Regression

    ERIC Educational Resources Information Center

    Lamb, John H.

    2007-01-01

    This article outlines a linear regression activity that engages learners, uses technology, and fosters cooperation. Students generated least-squares linear regression equations using TI-83 Plus[TM] graphing calculators, Microsoft[C] Excel, and paper-and-pencil calculations using derived normal equations to predict the 2004 presidential election.…

  16. Presidential Transition: The Experience of Two Community College Interim Presidents

    ERIC Educational Resources Information Center

    Thompson, Matthew D.

    2010-01-01

    The purpose of this qualitative case study was to understand the experiences of two community college interim presidents, their characteristics, and how they led institutions following an abrupt presidential departure. There were two fundamental questions framing this research study, 1. How do two interim community college presidents lead…

  17. The Effect of Religion on Candidate Preference in the 2008 and 2012 Republican Presidential Primaries

    PubMed Central

    Bradberry, Leigh A.

    2016-01-01

    Thanks to the work of politics and religion scholars, we now know a lot about the relationship between religion and voting in American presidential general elections. However, we know less about the influence of religion on individual vote choice in presidential primaries. This article fills that gap by exploring the relationship between religion and candidate preference in the 2008 and 2012 Republican primaries. Using pre-Super Tuesday surveys conducted by the Pew Research Center, I find that the Republican candidate who most explicitly appealed to religious voters (Mike Huckabee in 2008 and Rick Santorum in 2012) was the preferred candidate of Republican respondents who attended religious services at the highest levels, and that as attendance increased, so did the likelihood of preferring that candidate. I also find that identification as a born again Christian mattered to candidate preference. Specifically, born again Christians were more likely than non-born again Christians to prefer Huckabee to Mitt Romney, John McCain and Ron Paul in 2008, and Santorum to Romney in 2012. Although ideology was not the primary subject of this article, I find that ideology was also a statistically significant predictor of Republican candidate preference in both 2008 and 2012. This robust finding reinforces scholars’ prior work on the importance of ideology in explaining presidential primary vote choice. The overall findings of the paper provide evidence that religion variables can add to our understanding of why voters prefer one candidate over another in presidential primaries. PMID:27043438

  18. The Effect of Religion on Candidate Preference in the 2008 and 2012 Republican Presidential Primaries.

    PubMed

    Bradberry, Leigh A

    2016-01-01

    Thanks to the work of politics and religion scholars, we now know a lot about the relationship between religion and voting in American presidential general elections. However, we know less about the influence of religion on individual vote choice in presidential primaries. This article fills that gap by exploring the relationship between religion and candidate preference in the 2008 and 2012 Republican primaries. Using pre-Super Tuesday surveys conducted by the Pew Research Center, I find that the Republican candidate who most explicitly appealed to religious voters (Mike Huckabee in 2008 and Rick Santorum in 2012) was the preferred candidate of Republican respondents who attended religious services at the highest levels, and that as attendance increased, so did the likelihood of preferring that candidate. I also find that identification as a born again Christian mattered to candidate preference. Specifically, born again Christians were more likely than non-born again Christians to prefer Huckabee to Mitt Romney, John McCain and Ron Paul in 2008, and Santorum to Romney in 2012. Although ideology was not the primary subject of this article, I find that ideology was also a statistically significant predictor of Republican candidate preference in both 2008 and 2012. This robust finding reinforces scholars' prior work on the importance of ideology in explaining presidential primary vote choice. The overall findings of the paper provide evidence that religion variables can add to our understanding of why voters prefer one candidate over another in presidential primaries.

  19. The impact of presidential illness on the administration of Dwight D. Eisenhower.

    PubMed

    Gilbert, Robert E

    2012-01-01

    In March 2008, I published an article in this journal that examined the ways in which the White House managed the news--and minimized the political impact--of Dwight D. Eisenhower's massive 1955 heart attack. In addition, the analysis explored the manner in which Eisenhower himself, in handling this issue, had brilliantly "manipulated his medical team, safeguarded his image, cajoled his staff, confused the press, managed his advisers, dominated his party, and ran a campaign that was virtually impossible for the opposition to counteract" (p. 18). This article expands on my previous work by considering the ways in which Eisenhower's ill health had significant public policy repercussions that went beyond the immediate political effects evaluated in 2008. These included the drawbacks associated with Eisenhower's concept of "Team Government," a tragic war in the Middle East, a serious deterioration of the U.S. relationship with three very close allies and, finally, the beginnings of a presidentially led effort to add a much needed "presidential disability" amendment to the United States Constitution. These latter effects have been studied here through use of primary source materials located at the Dwight D. Eisenhower Presidential Library, commentaries written by Eisenhower himself, members of his family and other close associates and the voluminous secondary literature that has appeared over the years focusing on the Eisenhower presidency.

  20. Aeronautics and space report of the President, 1983 activities

    NASA Technical Reports Server (NTRS)

    1984-01-01

    Achievements in communication; space science; space transportation; aeronautics; and Earth resources and environment are summarized. Activities of the various Federal agencies and cooperation with NASA in these areas are described. The Presidential policy announcement on the endorsement of commercial operation of expendable launch vehicles is included. Tables show, the space activities budget; a historical budget summary, U.S. space launch vehicles; U.S. and Soviet manned spaceflights, 1961 to 1983; U.S. launched space probes, 1975 to 1983; U.S. launched scientific and applications satellites, 1978 to 1983; the U.S. spacecraft record; the world record of space launches successful in attaining Earth orbit or beyond; and successful U.S. launchings for 1983.

  1. Q-operators for the open Heisenberg spin chain

    NASA Astrophysics Data System (ADS)

    Frassek, Rouven; Szécsényi, István M.

    2015-12-01

    We construct Q-operators for the open spin-1/2 XXX Heisenberg spin chain with diagonal boundary matrices. The Q-operators are defined as traces over an infinite-dimensional auxiliary space involving novel types of reflection operators derived from the boundary Yang-Baxter equation. We argue that the Q-operators defined in this way are polynomials in the spectral parameter and show that they commute with transfer matrix. Finally, we prove that the Q-operators satisfy Baxter's TQ-equation and derive the explicit form of their eigenvalues in terms of the Bethe roots.

  2. Variability of ischiofemoral space dimensions with changes in hip flexion: an MRI study.

    PubMed

    Johnson, Adam C; Hollman, John H; Howe, Benjamin M; Finnoff, Jonathan T

    2017-01-01

    The primary aim of this study was to determine if ischiofemoral space (IFS) dimensions vary with changes in hip flexion as a result of placing a bolster behind the knees during magnetic resonance imaging (MRI). A secondary aim was to determine if IFS dimensions vary between supine and prone hip neutral positions. The study employed a prospective design. Sports medicine center within a tertiary care institution. Five male and five female adult subjects (age mean = 29.2, range = 23-35; body mass index [BMI] mean = 23.5, range = 19.5-26.6) were recruited to participate in the study. An axial, T1-weighted MRI sequence of the pelvis was obtained of each subject in a supine position with their hips in neutral and flexed positions, and in a prone position with their hips in neutral position. Supine hip flexion was induced by placing a standard, 9-cm-diameter MRI knee bolster under the subject's knees. The order of image acquisition (supine hip neutral, supine hip flexed, prone hip neutral) was randomized. The IFS dimensions were then measured on a separate workstation. The investigator performing the IFS measurements was blinded to the subject position for each image. The main outcome measurements were the IFS dimensions acquired with MRI. The mean IFS dimensions in the prone position were 28.25 mm (SD 5.91 mm, standard error mean 1.32 mm). In the supine hip neutral position, the IFS dimensions were 25.1 (SD 5.6) mm. The mean difference between the two positions of 3.15 (3.6) mm was statistically significant (95 % CI of the difference = 1.4 to 4.8 mm, t 19  = 3.911, p = .001). The mean IFS dimensions in the hip flexed position were 36.9 (SD 5.7) mm. The mean difference between the two supine positions of 11.8 (4.1) mm was statistically significant (95 % CI of the difference = 9.9 to 13.7 mm, t 19  = 12.716, p < .001). Our findings demonstrate that the IFS measurements obtained with MRI are dependent upon patient positioning

  3. Genetic Contributions to Changes of Fiber Tracts of Ventral Visual Stream in 22q11.2 Deletion Syndrome

    PubMed Central

    Kikinis, Zora; Makris, Nikos; Finn, Christine T.; Bouix, Sylvain; Lucia, Diandra; Coleman, Michael J.; Tworog-Dube, Erica; Kikinis, Ron; Kucherlapati, Raju; Shenton, Martha E.; Kubicki, Marek

    2013-01-01

    Patients with 22q11.2 deletion syndrome (22q11.2DS) represent a population at high risk for developing schizophrenia, as well as learning disabilities. Deficits in visuo-spatial memory are thought to underlie some of the cognitive disabilities. Neuronal substrates of visuo-spatial memory include the inferior fronto-occipital fasciculus (IFOF) and the inferior longitudinal fasciculus (ILF), two tracts that comprise the ventral visual stream. Diffusion Tensor Magnetic Resonance Imaging (DT-MRI) is an established method to evaluate white matter (WM) connections in vivo. DT-MRI scans of nine 22q11.2DS young adults and nine matched healthy subjects were acquired. Tractography of the IFOF and the ILF was performed. DT-MRI indices, including Fractional anisotropy (FA) (measure of WM changes), axial diffusivity (AD, measure of axonal changes) and radial diffusivity (RD, measure of myelin changes) of each of the tracts and each group were measured and compared. The 22q11.2DS group showed statistically significant reductions of FA in IFOF in the left hemisphere. Additionally, reductions of AD were found in the IFOF and the ILF in both hemispheres. These findings might be the consequence of axonal changes, which is possibly due to fewer, thinner, or less organized fibers. No changes in RD were detected in any of the tracts delineated, which is in contrast to findings in schizophrenia patients where increases in RD are believed to be indicative of demyelination. We conclude that reduced axonal changes may be key to understanding the underlying pathology of WM leading to the visuo-spatial phenotype in 22q11.2DS. PMID:23612843

  4. The Presidential Sound: From Orotund to Instructional Speech, 1892-1912

    ERIC Educational Resources Information Center

    Goodale, Greg

    2010-01-01

    At the turn of the twentieth century, the sound of presidential address changed from an orotund style to an instructional style. The orotund style had featured the careful pronunciation of consonants, elongated vowels, trilled r's and repeated declamations. The instructional style, on the other hand, mimicked the conversational lectures of the…

  5. A Functional Analysis of the 1988 Bush-Dukakis Presidential Debates.

    ERIC Educational Resources Information Center

    Benoit, William L.; Brazeal, LeAnn M.

    2002-01-01

    Applies the Functional Theory of Political Campaign Discourse to the 1988 presidential debates between George Bush and Michael Dukakis. Challenges the notion that this campaign was mostly negative. Concludes that despite the belief that modern campaigns are devoid of substance, these debates stressed policy about twice as much as character. (SG)

  6. Courage in Mission: Presidential Leadership in the Church-Related College.

    ERIC Educational Resources Information Center

    Dagley, Duane H., Ed.

    The following essays on presidential leadership by 12 presidents and former presidents of church-related colleges are presented in five sections: Section 1, The President and Institutional Challenge, contains "A Call for the President as Spiritual Director" (Duane H. Bagley); Section 2, Articulating the Mission, contains "The President and the…

  7. MRI in ocular drug delivery

    PubMed Central

    Li, S. Kevin; Lizak, Martin J.; Jeong, Eun-Kee

    2008-01-01

    Conventional pharmacokinetic methods for studying ocular drug delivery are invasive and cannot be conveniently applied to humans. The advancement of MRI technology has provided new opportunities in ocular drug-delivery research. MRI provides a means to non-invasively and continuously monitor ocular drug-delivery systems with a contrast agent or compound labeled with a contrast agent. It is a useful technique in pharmacokinetic studies, evaluation of drug-delivery methods, and drug-delivery device testing. Although the current status of the technology presents some major challenges to pharmaceutical research using MRI, it has a lot of potential. In the past decade, MRI has been used to examine ocular drug delivery via the subconjunctival route, intravitreal injection, intrascleral injection to the suprachoroidal space, episcleral and intravitreal implants, periocular injections, and ocular iontophoresis. In this review, the advantages and limitations of MRI in the study of ocular drug delivery are discussed. Different MR contrast agents and MRI techniques for ocular drug-delivery research are compared. Ocular drug-delivery studies using MRI are reviewed. PMID:18186077

  8. Primary Cystic Lesions of the Retrorectal Space: MRI Evaluation and Clinical Assessment.

    PubMed

    Dwarkasing, Roy S; Verschuuren, Sylvia I; van Leenders, Geert J L H; Braun, Loes M M; Krestin, Gabriel P; Schouten, W Rudolph

    2017-10-01

    The purpose of this study was to assess the a priori chance that primary cystic lesions of the retrorectal space are malignant and to investigate MRI characteristics that indicate malignancy. Patients referred to a center for colorectal surgery were recruited from 2000 to 2014. Lesions were proven by clinical assessment and histopathology. MRI was performed at 1.5 T with examinations evaluated by two radiologists. Interobserver agreement was assessed (Cohen kappa) and differences between malignant and benign lesions calculated (Fisher exact test). Twenty-eight patients (22 women, six men; age range, 18-70 years) with 31 lesions were included. Lesions were categorized as tailgut cysts (n = 16, 52%), teratomas (n = 9, 29%), lesions of colorectal origin (n = 4, 13%), or neurogenic lesions (n = 2, 6%). Five patients (18%) had malignant lesions. Colorectal lesions had the highest percentage of malignancy (3/4, 75%). A solid tissue component was found in all five (100%) malignant lesions and two (8%) of the benign lesions, which were both teratomas (p < 0.05). Sensitivity and specificity for malignancy according to the presence of a solid tissue component was 100% (5/5) and 92% (24/26). For unilocularity, multilocularity, debris, septa, and wall thickening, differences were not significant. Interobserver agreement was excellent (κ = 1) for all characteristics except debris (κ = 0.795). The majority of retrorectal cystic lesions are benign. The presence of a solid tissue component should raise suspicion for malignancy.

  9. Validation of oxygen extraction fraction measurement by qBOLD technique.

    PubMed

    He, Xiang; Zhu, Mingming; Yablonskiy, Dmitriy A

    2008-10-01

    Measurement of brain tissue oxygen extraction fraction (OEF) in both baseline and functionally activated states can provide important information on brain functioning in health and disease. The recently proposed quantitative BOLD (qBOLD) technique is MRI-based and provides a regional in vivo OEF measurement (He and Yablonskiy, MRM 2007, 57:115-126). It is based on a previously developed analytical BOLD model and incorporates prior knowledge about the brain tissue composition including the contributions from grey matter, white matter, cerebrospinal fluid, interstitial fluid and intravascular blood. The qBOLD model also allows for the separation of contributions to the BOLD signal from OEF and the deoxyhemoglobin containing blood volume (DBV). The objective of this study is to validate OEF measurements provided by the qBOLD approach. To this end we use a rat model and compare qBOLD OEF measurements against direct measurements of the blood oxygenation level obtained from venous blood drawn directly from the superior sagittal sinus. The cerebral venous oxygenation level of the rat was manipulated by utilizing different anestheisa methods. The study demonstrates a very good agreement between qBOLD approach and direct measurements. (c) 2008 Wiley-Liss, Inc.

  10. Internationalization on HBCU Campuses and the Role of Presidential Leadership

    ERIC Educational Resources Information Center

    Diabate, Dafina Blacksher

    2017-01-01

    This study seeks to examine the role of presidential leadership in internationalization on historically Black college and university (HBCU) campuses. HBCUs comprise a small but important segment of U.S. higher education, as they are responsible for 20% of African American graduates in the country. Unfortunately, many of these institutions have yet…

  11. The Presidential Address 2014. Teaching and Learning: The Long View

    ERIC Educational Resources Information Center

    Roberts, Alice

    2014-01-01

    This article presents the transcript of the Presidential Address delivered to the Association for Science Education Annual Conference held at the University of Birmingham in January 2014. In her address, Alice Roberts traces the evolution of various features that are often thought to make humans different from other animals. Examples such as…

  12. The limit distribution in the q-CLT for q\\,\\geqslant \\,1 is unique and can not have a compact support

    NASA Astrophysics Data System (ADS)

    Umarov, Sabir; Tsallis, Constantino

    2016-10-01

    In a paper by Umarov et al (2008 Milan J. Math. 76 307-28), a generalization of the Fourier transform, called the q-Fourier transform, was introduced and applied for the proof of a q-generalized central limit theorem (q-CLT). Subsequently, Hilhorst illustrated (2009 Braz. J. Phys. 39 371-9 2010 J. Stat. Mech. P10023) that the q-Fourier transform for q\\gt 1, is not invertible in the space of density functions. Indeed, using an invariance principle, he constructed a family of densities with the same q-Fourier transform and noted that ‘as a consequence, the q-CLT falls short of achieving its stated goal’. The distributions constructed there have compact support. We prove now that the limit distribution in the q-CLT is unique and can not have a compact support. This result excludes all the possible counterexamples which can be constructed using the invariance principle and fills the gap mentioned by Hilhorst.

  13. Analysis of swing voter in the Indonesian election of 2014 presidential candidates using Twitter data

    NASA Astrophysics Data System (ADS)

    Alfarisy, Muhammad Salman; Putra, Rizki M.; Liong, The Houw; Purqon, Acep

    2015-09-01

    Ahead of the 2014 elections would be interesting to predict which candidate will hold the highest authority in the Republic of Indonesia. Entering the 2014 presidential election there is no infidelity tendency of voters who initially settled on a party or a candidate then choose another party or candidate in the next election. Changes in the tendency to make the condition of society in a state that has not been to given the choice of a candidate is commonly called swing voters. On this occasion, an examination of the swing voters who use social media twitter. By utilizing the advanced search facility to collect data from the response of tweeps (twitter users) on the twitter to Indonesian presidential candidate. The data will be used to describe how much the popularity of a candidate among tweeps, knowing the candidates who have the largest positive response and negative response, as well as the growing popularity of the candidate. The data is expected to predict the RI presidential candidate in 2014.

  14. Presidential addresses of the Royal Society of Tropical Medicine and Hygiene: 1907–2013

    PubMed Central

    Hay, Simon I.; McHugh, Gerri M.

    2013-01-01

    Presidents have been required to give an inaugural address on commencing office at the Royal Society of Tropical Medicine and Hygiene (RSTMH) since its foundation in 1907. All presidential addresses were identified, sourced and assembled into an annotated bibliography. The majority of presidential addresses have been published in Transactions of the Royal Society of Tropical Medicine and Hygiene. Unpublished and in some cases ‘lost’ contributions have now been sourced where possible and archived at the RSTMH. This unique, rich and rewarding archive provides a vista into the development of the RSTMH and the discipline of tropical medicine. The archive is freely available to all. PMID:24026462

  15. The Function of Epideictic and Deliberative Strategies in Presidential Crisis Rhetoric.

    ERIC Educational Resources Information Center

    Dow, Bonnie J.

    1989-01-01

    Argues for a revised perspective on presidential crisis rhetoric informed by an understanding of differing exigencies and functions. Uses speeches by Ronald Reagan to examine two types of crisis rhetoric. Concludes that crisis rhetoric can not be viewed as a homogeneous type of discourse. (MM)

  16. 75 FR 69990 - Application for Presidential Permit; Northern Pass Transmission LLC

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-16

    ... constructed in Franklin, New Hampshire. At the Franklin converter terminal the electric energy would be... marketplace, DOE has consistently expressed its policy that cross-border trade in electric energy should be... DEPARTMENT OF ENERGY [OE Docket No. PP-371] Application for Presidential Permit; Northern Pass...

  17. 10 CFR 205.328 - Environmental requirements for Presidential Permits-Alternative 1.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Facilities for Transmission of Electric Energy at International Boundaries § 205.328 Environmental... 10 Energy 3 2011-01-01 2011-01-01 false Environmental requirements for Presidential Permits-Alternative 1. 205.328 Section 205.328 Energy DEPARTMENT OF ENERGY OIL ADMINISTRATIVE PROCEDURES AND SANCTIONS...

  18. 10 CFR 205.329 - Environmental requirements for Presidential Permits-Alternative 2.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Facilities for Transmission of Electric Energy at International Boundaries § 205.329 Environmental... 10 Energy 3 2011-01-01 2011-01-01 false Environmental requirements for Presidential Permits-Alternative 2. 205.329 Section 205.329 Energy DEPARTMENT OF ENERGY OIL ADMINISTRATIVE PROCEDURES AND SANCTIONS...

  19. Time-resolved 3D pulmonary perfusion MRI: comparison of different k-space acquisition strategies at 1.5 and 3 T.

    PubMed

    Attenberger, Ulrike I; Ingrisch, Michael; Dietrich, Olaf; Herrmann, Karin; Nikolaou, Konstantin; Reiser, Maximilian F; Schönberg, Stefan O; Fink, Christian

    2009-09-01

    Time-resolved pulmonary perfusion MRI requires both high temporal and spatial resolution, which can be achieved by using several nonconventional k-space acquisition techniques. The aim of this study is to compare the image quality of time-resolved 3D pulmonary perfusion MRI with different k-space acquisition techniques in healthy volunteers at 1.5 and 3 T. Ten healthy volunteers underwent contrast-enhanced time-resolved 3D pulmonary MRI on 1.5 and 3 T using the following k-space acquisition techniques: (a) generalized autocalibrating partial parallel acquisition (GRAPPA) with an internal acquisition of reference lines (IRS), (b) GRAPPA with a single "external" acquisition of reference lines (ERS) before the measurement, and (c) a combination of GRAPPA with an internal acquisition of reference lines and view sharing (VS). The spatial resolution was kept constant at both field strengths to exclusively evaluate the influences of the temporal resolution achieved with the different k-space sampling techniques on image quality. The temporal resolutions were 2.11 seconds IRS, 1.31 seconds ERS, and 1.07 VS at 1.5 T and 2.04 seconds IRS, 1.30 seconds ERS, and 1.19 seconds VS at 3 T.Image quality was rated by 2 independent radiologists with regard to signal intensity, perfusion homogeneity, artifacts (eg, wrap around, noise), and visualization of pulmonary vessels using a 3 point scale (1 = nondiagnostic, 2 = moderate, 3 = good). Furthermore, the signal-to-noise ratio in the lungs was assessed. At 1.5 T the lowest image quality (sum score: 154) was observed for the ERS technique and the highest quality for the VS technique (sum score: 201). In contrast, at 3 T images acquired with VS were hampered by strong artifacts and image quality was rated significantly inferior (sum score: 137) compared with IRS (sum score: 180) and ERS (sum score: 174). Comparing 1.5 and 3 T, in particular the overall rating of the IRS technique (sum score: 180) was very similar at both field

  20. Convexity and concavity constants in Lorentz and Marcinkiewicz spaces

    NASA Astrophysics Data System (ADS)

    Kaminska, Anna; Parrish, Anca M.

    2008-07-01

    We provide here the formulas for the q-convexity and q-concavity constants for function and sequence Lorentz spaces associated to either decreasing or increasing weights. It yields also the formula for the q-convexity constants in function and sequence Marcinkiewicz spaces. In this paper we extent and enhance the results from [G.J.O. Jameson, The q-concavity constants of Lorentz sequence spaces and related inequalities, Math. Z. 227 (1998) 129-142] and [A. Kaminska, A.M. Parrish, The q-concavity and q-convexity constants in Lorentz spaces, in: Banach Spaces and Their Applications in Analysis, Conference in Honor of Nigel Kalton, May 2006, Walter de Gruyter, Berlin, 2007, pp. 357-373].

  1. Fiber estimation and tractography in diffusion MRI: Development of simulated brain images and comparison of multi-fiber analysis methods at clinical b-values

    PubMed Central

    Wilkins, Bryce; Lee, Namgyun; Gajawelli, Niharika; Law, Meng; Leporé, Natasha

    2015-01-01

    Advances in diffusion-weighted magnetic resonance imaging (DW-MRI) have led to many alternative diffusion sampling strategies and analysis methodologies. A common objective among methods is estimation of white matter fiber orientations within each voxel, as doing so permits in-vivo fiber-tracking and the ability to study brain connectivity and networks. Knowledge of how DW-MRI sampling schemes affect fiber estimation accuracy, and consequently tractography and the ability to recover complex white-matter pathways, as well as differences between results due to choice of analysis method and which method(s) perform optimally for specific data sets, all remain important problems, especially as tractography-based studies become common. In this work we begin to address these concerns by developing sets of simulated diffusion-weighted brain images which we then use to quantitatively evaluate the performance of six DW-MRI analysis methods in terms of estimated fiber orientation accuracy, false-positive (spurious) and false-negative (missing) fiber rates, and fiber-tracking. The analysis methods studied are: 1) a two-compartment “ball and stick” model (BSM) (Behrens et al., 2003); 2) a non-negativity constrained spherical deconvolution (CSD) approach (Tournier et al., 2007); 3) analytical q-ball imaging (QBI) (Descoteaux et al., 2007); 4) q-ball imaging with Funk-Radon and Cosine Transform (FRACT) (Haldar and Leahy, 2013); 5) q-ball imaging within constant solid angle (CSA) (Aganj et al., 2010); and 6) a generalized Fourier transform approach known as generalized q-sampling imaging (GQI) (Yeh et al., 2010). We investigate these methods using 20, 30, 40, 60, 90 and 120 evenly distributed q-space samples of a single shell, and focus on a signal-to-noise ratio (SNR = 18) and diffusion-weighting (b = 1000 s/mm2) common to clinical studies. We found the BSM and CSD methods consistently yielded the least fiber orientation error and simultaneously greatest detection rate of

  2. Fiber estimation and tractography in diffusion MRI: development of simulated brain images and comparison of multi-fiber analysis methods at clinical b-values.

    PubMed

    Wilkins, Bryce; Lee, Namgyun; Gajawelli, Niharika; Law, Meng; Leporé, Natasha

    2015-04-01

    Advances in diffusion-weighted magnetic resonance imaging (DW-MRI) have led to many alternative diffusion sampling strategies and analysis methodologies. A common objective among methods is estimation of white matter fiber orientations within each voxel, as doing so permits in-vivo fiber-tracking and the ability to study brain connectivity and networks. Knowledge of how DW-MRI sampling schemes affect fiber estimation accuracy, tractography and the ability to recover complex white-matter pathways, differences between results due to choice of analysis method, and which method(s) perform optimally for specific data sets, all remain important problems, especially as tractography-based studies become common. In this work, we begin to address these concerns by developing sets of simulated diffusion-weighted brain images which we then use to quantitatively evaluate the performance of six DW-MRI analysis methods in terms of estimated fiber orientation accuracy, false-positive (spurious) and false-negative (missing) fiber rates, and fiber-tracking. The analysis methods studied are: 1) a two-compartment "ball and stick" model (BSM) (Behrens et al., 2003); 2) a non-negativity constrained spherical deconvolution (CSD) approach (Tournier et al., 2007); 3) analytical q-ball imaging (QBI) (Descoteaux et al., 2007); 4) q-ball imaging with Funk-Radon and Cosine Transform (FRACT) (Haldar and Leahy, 2013); 5) q-ball imaging within constant solid angle (CSA) (Aganj et al., 2010); and 6) a generalized Fourier transform approach known as generalized q-sampling imaging (GQI) (Yeh et al., 2010). We investigate these methods using 20, 30, 40, 60, 90 and 120 evenly distributed q-space samples of a single shell, and focus on a signal-to-noise ratio (SNR = 18) and diffusion-weighting (b = 1000 s/mm(2)) common to clinical studies. We found that the BSM and CSD methods consistently yielded the least fiber orientation error and simultaneously greatest detection rate of fibers. Fiber detection

  3. Low Gravity Materials Science Research for Space Exploration

    NASA Technical Reports Server (NTRS)

    Clinton, R. G., Jr.; Semmes, Edmund B.; Schlagheck, Ronald A.; Bassler, Julie A.; Cook, Mary Beth; Wargo, Michael J.; Sanders, Gerald B.; Marzwell, Neville I.

    2004-01-01

    On January 14, 2004, the President of the United States announced a new vision for the United States civil space program. The Administrator of the National Aeronautics and Space Administration (NASA) has the responsibility to implement this new vision. The President also created a Presidential Commission 'to obtain recommendations concerning implementation of the new vision for space exploration.' The President's Commission recognized that achieving the exploration objectives would require significant technical innovation, research, and development in focal areas defined as 'enabling technologies.' Among the 17 enabling technologies identified for initial focus were advanced structures; advanced power and propulsion; closed-loop life support and habitability; extravehicular activity system; autonomous systems and robotics; scientific data collection and analysis; biomedical risk mitigation; and planetary in situ resource utilization. The Commission also recommended realignment of NASA Headquarters organizations to support the vision for space exploration. NASA has aggressively responded in its planning to support the vision for space exploration and with the current considerations of the findings and recommendations from the Presidential Commission. This presentation will examine the transformation and realignment activities to support the vision for space exploration that are underway in the microgravity materials science program. The heritage of the microgravity materials science program, in the context of residence within the organizational structure of the Office of Biological and Physical Research, and thematic and sub-discipline based research content areas, will be briefly examined as the starting point for the ongoing transformation. Overviews of future research directions will be presented and the status of organizational restructuring at NASA Headquarters, with respect to influences on the microgravity materials science program, will be discussed

  4. An in vivo MRI Template Set for Morphometry, Tissue Segmentation, and fMRI Localization in Rats

    PubMed Central

    Valdés-Hernández, Pedro Antonio; Sumiyoshi, Akira; Nonaka, Hiroi; Haga, Risa; Aubert-Vásquez, Eduardo; Ogawa, Takeshi; Iturria-Medina, Yasser; Riera, Jorge J.; Kawashima, Ryuta

    2011-01-01

    Over the last decade, several papers have focused on the construction of highly detailed mouse high field magnetic resonance image (MRI) templates via non-linear registration to unbiased reference spaces, allowing for a variety of neuroimaging applications such as robust morphometric analyses. However, work in rats has only provided medium field MRI averages based on linear registration to biased spaces with the sole purpose of approximate functional MRI (fMRI) localization. This precludes any morphometric analysis in spite of the need of exploring in detail the neuroanatomical substrates of diseases in a recent advent of rat models. In this paper we present a new in vivo rat T2 MRI template set, comprising average images of both intensity and shape, obtained via non-linear registration. Also, unlike previous rat template sets, we include white and gray matter probabilistic segmentations, expanding its use to those applications demanding prior-based tissue segmentation, e.g., statistical parametric mapping (SPM) voxel-based morphometry. We also provide a preliminary digitalization of latest Paxinos and Watson atlas for anatomical and functional interpretations within the cerebral cortex. We confirmed that, like with previous templates, forepaw and hindpaw fMRI activations can be correctly localized in the expected atlas structure. To exemplify the use of our new MRI template set, were reported the volumes of brain tissues and cortical structures and probed their relationships with ontogenetic development. Other in vivo applications in the near future can be tensor-, deformation-, or voxel-based morphometry, morphological connectivity, and diffusion tensor-based anatomical connectivity. Our template set, freely available through the SPM extension website, could be an important tool for future longitudinal and/or functional extensive preclinical studies. PMID:22275894

  5. A Presidential Election Simulation: Creating a School-Wide Interdisciplinary Program

    ERIC Educational Resources Information Center

    Joyce, Helen M.

    2008-01-01

    Given the low turnout among younger voters, it is important to seek innovative ways of engaging students in the electoral process, and a presidential year like this one offers exciting opportunities for doing so. In this article, the author describes her experiences with a schoolwide project designed by herself and colleagues that simulates the…

  6. RF system calibration for global Q matrix determination.

    PubMed

    Padormo, Francesco; Beqiri, Arian; Malik, Shaihan J; Hajnal, Joseph V

    2016-06-01

    The use of multiple transmission channels (known as Parallel Transmission, or PTx) provides increased control of the MRI signal formation process. This extra flexibility comes at a cost of uncertainty of the power deposited in the patient under examination: the electric fields produced by each transmitter can interfere in such a way to lead to excessively high heating. Although it is not possible to determine local heating, the global Q matrix (which allows the whole-body Specific Absorption Rate (SAR) to be known for any PTx pulse) can be measured in-situ by monitoring the power incident upon and reflected by each transmit element during transmission. Recent observations have shown that measured global Q matrices can be corrupted by losses between the coil array and location of power measurement. In this work we demonstrate that these losses can be accounted for, allowing accurate global Q matrix measurement independent of the location of the power measurement devices. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

  7. Genetic Algorithm Optimizes Q-LAW Control Parameters

    NASA Technical Reports Server (NTRS)

    Lee, Seungwon; von Allmen, Paul; Petropoulos, Anastassios; Terrile, Richard

    2008-01-01

    A document discusses a multi-objective, genetic algorithm designed to optimize Lyapunov feedback control law (Q-law) parameters in order to efficiently find Pareto-optimal solutions for low-thrust trajectories for electronic propulsion systems. These would be propellant-optimal solutions for a given flight time, or flight time optimal solutions for a given propellant requirement. The approximate solutions are used as good initial solutions for high-fidelity optimization tools. When the good initial solutions are used, the high-fidelity optimization tools quickly converge to a locally optimal solution near the initial solution. Q-law control parameters are represented as real-valued genes in the genetic algorithm. The performances of the Q-law control parameters are evaluated in the multi-objective space (flight time vs. propellant mass) and sorted by the non-dominated sorting method that assigns a better fitness value to the solutions that are dominated by a fewer number of other solutions. With the ranking result, the genetic algorithm encourages the solutions with higher fitness values to participate in the reproduction process, improving the solutions in the evolution process. The population of solutions converges to the Pareto front that is permitted within the Q-law control parameter space.

  8. Cosmological Distortions in Redshift Space

    NASA Astrophysics Data System (ADS)

    Ryden, Barbara S.

    1995-05-01

    The long-sought value of q_0, the deceleration parameter, remains elusive. One method of finding q_0 is to measure the distortions of large scale structure in redshift space. If the Hubble constant changes with time, then the mapping between redshift space and real space is nonlinear, even in the absence of peculiar motions. When q_0 > -1, structures in redshift space will be distorted along the line of sight; the distortion is proportional to (1 + q_0 ) z in the limit that the redshift z is small. The cosmological distortions at z <= 0.2 can be found by measuring the shapes of voids in redshift surveys of galaxies (such as the upcoming Sloane Digital Sky Survey). The cosmological distortions are masked to some extent by the distortions caused by small-scale peculiar velocities; it is difficult to measure the shape of a void when the fingers of God are poking into it. The cosmological distortions at z ~ 1 can be found by measuring the correlation function of quasars as a function of redshift and of angle relative to the line of sight. Finding q_0 by measuring distortions in redshift space, like the classical methods of determining q_0, is simple and elegant in principle but complicated and messy in practice.

  9. Molecular classification of patients with grade II/III glioma using quantitative MRI characteristics.

    PubMed

    Bahrami, Naeim; Hartman, Stephen J; Chang, Yu-Hsuan; Delfanti, Rachel; White, Nathan S; Karunamuni, Roshan; Seibert, Tyler M; Dale, Anders M; Hattangadi-Gluth, Jona A; Piccioni, David; Farid, Nikdokht; McDonald, Carrie R

    2018-06-02

    Molecular markers of WHO grade II/III glioma are known to have important prognostic and predictive implications and may be associated with unique imaging phenotypes. The purpose of this study is to determine whether three clinically relevant molecular markers identified in gliomas-IDH, 1p/19q, and MGMT status-show distinct quantitative MRI characteristics on FLAIR imaging. Sixty-one patients with grade II/III gliomas who had molecular data and MRI available prior to radiation were included. Quantitative MRI features were extracted that measured tissue heterogeneity (homogeneity and pixel correlation) and FLAIR border distinctiveness (edge contrast; EC). T-tests were conducted to determine whether patients with different genotypes differ across the features. Logistic regression with LASSO regularization was used to determine the optimal combination of MRI and clinical features for predicting molecular subtypes. Patients with IDH wildtype tumors showed greater signal heterogeneity (p = 0.001) and lower EC (p = 0.008) within the FLAIR region compared to IDH mutant tumors. Among patients with IDH mutant tumors, 1p/19q co-deleted tumors had greater signal heterogeneity (p = 0.002) and lower EC (p = 0.005) compared to 1p/19q intact tumors. MGMT methylated tumors showed lower EC (p = 0.03) compared to the unmethylated group. The combination of FLAIR border distinctness, heterogeneity, and pixel correlation optimally classified tumors by IDH status. Quantitative imaging characteristics of FLAIR heterogeneity and border pattern in grade II/III gliomas may provide unique information for determining molecular status at time of initial diagnostic imaging, which may then guide subsequent surgical and medical management.

  10. Documentation Supporting D.C. Water's Request for Reimbursement After the 2009 Presidential Inauguration

    EPA Pesticide Factsheets

    DC Water located in Washington, DC incurred costs for activities related to the Presidential Inauguration in January 2009. Support included the purchase and installation of special manhole covers with security features.

  11. Comparison of air space measurement imaged by CT, small-animal CT, and hyperpolarized Xe MRI

    NASA Astrophysics Data System (ADS)

    Madani, Aniseh; White, Steven; Santyr, Giles; Cunningham, Ian

    2005-04-01

    Lung disease is the third leading cause of death in the western world. Lung air volume measurements are thought to be early indicators of lung disease and markers in pharmaceutical research. The purpose of this work is to develop a lung phantom for assessing and comparing the quantitative accuracy of hyperpolarized xenon 129 magnetic resonance imaging (HP 129Xe MRI), conventional computed tomography (HRCT), and highresolution small-animal CT (μCT) in measuring lung gas volumes. We developed a lung phantom consisting of solid cellulose acetate spheres (1, 2, 3, 4 and 5 mm diameter) uniformly packed in circulated air or HP 129Xe gas. Air volume is estimated based on simple thresholding algorithm. Truth is calculated from the sphere diameters and validated using μCT. While this phantom is not anthropomorphic, it enables us to directly measure air space volume and compare these imaging methods as a function of sphere diameter for the first time. HP 129Xe MRI requires partial volume analysis to distinguish regions with and without 129Xe gas and results are within %5 of truth but settling of the heavy 129Xe gas complicates this analysis. Conventional CT demonstrated partial-volume artifacts for the 1mm spheres. μCT gives the most accurate air-volume results. Conventional CT and HP 129Xe MRI give similar results although non-uniform densities of 129Xe require more sophisticated algorithms than simple thresholding. The threshold required to give the true air volume in both HRCT and μCT, varies with sphere diameters calling into question the validity of thresholding method.

  12. Y spaces and global smooth solution of fractional Navier-Stokes equations with initial value in the critical oscillation spaces

    NASA Astrophysics Data System (ADS)

    Yang, Qixiang; Yang, Haibo

    2018-04-01

    For fractional Navier-Stokes equations and critical initial spaces X, one used to establish the well-posedness in the solution space which is contained in C (R+ , X). In this paper, for heat flow, we apply parameter Meyer wavelets to introduce Y spaces Y m , β where Y m , β is not contained in C (R+, B˙∞ 1 - 2 β , ∞). Consequently, for 1/2 < β < 1, we establish the global well-posedness of fractional Navier-Stokes equations with small initial data in all the critical oscillation spaces. The critical oscillation spaces may be any Besov-Morrey spaces (B˙p,q γ1 ,γ2 (Rn)) n or any Triebel-Lizorkin-Morrey spaces (F˙p,q γ1 ,γ2 (Rn)) n where 1 ≤ p , q ≤ ∞ , 0 ≤γ2 ≤ n/p, γ1 -γ2 = 1 - 2 β. These critical spaces include many known spaces. For example, Besov spaces, Sobolev spaces, Bloch spaces, Q-spaces, Morrey spaces and Triebel-Lizorkin spaces etc.

  13. 7T Magnetization Transfer and Chemical Exchange Saturation Transfer MRI of Cortical Gray Matter: Can We Detect Neurochemical and Macromolecular Abnormalities

    DTIC Science & Technology

    2015-10-01

    with fMRI , and CEST acquisitions. Analysis hurdles were noted in the qMT, which we discuss here. Recruitment continues in the MS cohort (all healthy...Saturation Transfer (CEST) • Magnetization Transfer (MT) • Brain • Cortical Gray Matter (cGM) • Multiple Sclerosis (MS) • Functional MRI ( fMRI ) • Pool Size...MPRAGE Anatomical – 2:12 • fMRI Resting State – 8:34 • fMRI N-Back task – 8:30 • fMRI Trailmaking task – 4:14 The current scan time for all scans is

  14. Robert Devlin presented with 2017 Presidential Rank Award for Me

    NASA Image and Video Library

    2018-04-23

    On April 23, 2018, Todd May presented Robert (Bob) Devlin with the 2017 Presidential Rank Award for Meritorious Executive. This is the second-highest award conferred by the President of the United States. Individuals receiving this award are recognized for sustained accomplishments and no more than five percent of career SES or SL/ST members may receive this award.

  15. Participating in commercial space ventures: Introduction to NASA Centers for the Commercial Development of Space and the Cooperative Agreements Programs

    NASA Technical Reports Server (NTRS)

    1990-01-01

    In response to a Presidential directive, NASA has implemented a space policy which actively supports and encourages U.S. industry investment and participation in commercial space ventures. NASA's Office of Commercial Programs (OCP) has played a significant role in stimulating the growth of commercial space activity. Through a variety of programs, OCP encourages commercial interest and involvement in space endeavors by providing access to NASA resources and opportunities for the emerging space industry to reduce the technical, financial, and business risks associated with space-related activities. This manual describes NASA's Commercial Uses of Space Program and introduces participants to four major OCP Commercial programs: Technology Utilization (TU), Small Business Innovation Research (SBIR), Centers for the Commercial Development of Space Flight Agreement (CCDSFA), and Cooperative Agreements Programs. The objective of this manual is to assist U.S. industry identify and pursue the appropriate agreement for participation in a commercial space venture.

  16. The NCSS Presidential Addresses, 1936-1969: Perspectives on the Social Studies.

    ERIC Educational Resources Information Center

    Previte, Mark A., Ed.; Sheehan, James J., Ed.

    This collection of the National Council for the Social Studies (NCSS) presidential addresses seeks to provide a valuable window to the history of NCSS and the field of social studies. Following the "Introduction" (James J. Sheehan), addresses appear chronologically: 1936 "Social Sanity through the Social Studies" (R. O.…

  17. Team Teaching Political Communication: The 2000 Campus U.S. Presidential Campaign.

    ERIC Educational Resources Information Center

    Hardeman, Keith T.; Jefferson, Kurt W.

    The closeness of the 2000 presidential election clearly demonstrated that the country was divided philosophically and politically. The authors of this paper, a speech communication professor and a political science professor at Westminster College in Missouri, capitalized on that division based upon their diametrically opposed political views by…

  18. The association between county political inclination and obesity: Results from the 2012 presidential election in the United States.

    PubMed

    Shin, Michael E; McCarthy, William J

    2013-11-01

    We examined whether stable, county-level, voter preferences were significantly associated with county-level obesity prevalence using data from the 2012 US Presidential election. County voting preference for the 2012 Republican Party presidential candidate was used as a proxy for voter endorsement of personal responsibility approaches to reducing population obesity risk versus approaches featuring government-sponsored, multi-sectoral efforts like those recommended by the Centers for Disease Control Centers for Disease Control (CDC, 2009). Cartographic visualization and spatial analysis were used to evaluate the geographic clustering of obesity prevalence rates by county, and county-level support for the Republican Party candidate in the 2012 U.S. presidential election. The spatial analysis informed the spatial econometric approach employed to model the relationship between political preferences and other covariates with obesity prevalence. After controlling for poverty rate, percent African American and Latino populations, educational attainment, and spatial autocorrelation in the error term, we found that higher county-level obesity prevalence rates were associated with higher levels of support for the 2012 Republican Party presidential candidate. Future public health efforts to understand and reduce obesity risk may benefit from increased surveillance of this and similar linkages between political preferences and health risks. © 2013.

  19. Presidential Space Policy Directs NASA to Return Humans to Moon

    NASA Image and Video Library

    2017-12-11

    President Donald Trump signed a new Space Policy Directive-1 at the White House on Monday, Dec. 11, directing NASA’s human spaceflight program back to the Moon, as recommended by the National Space Council.    The directive calls for NASA to lead an innovative and sustainable program of exploration with commercial and international partners to enable human expansion across the solar system, and to bring back to Earth new knowledge and opportunities for human advancement. This effort will more effectively organize government, private industry, and international efforts toward returning humans on the Moon, and will lay the foundation that will eventually enable human exploration of Mars.

  20. All (4,1): Sigma models with (4 , q) off-shell supersymmetry

    NASA Astrophysics Data System (ADS)

    Hull, Chris; Lindström, Ulf

    2017-03-01

    Off-shell (4 , q) supermultiplets in 2-dimensions are constructed for q = 1 , 2 , 4. These are used to construct sigma models whose target spaces are hyperkähler with torsion. The off-shell supersymmetry implies the three complex structures are simultaneously integrable and allows us to construct actions using extended superspace and projective superspace, giving an explicit construction of the target space geometries.

  1. Distortion correction for diffusion-weighted MRI tractography and fMRI in the temporal lobes.

    PubMed

    Embleton, Karl V; Haroon, Hamied A; Morris, David M; Ralph, Matthew A Lambon; Parker, Geoff J M

    2010-10-01

    Single shot echo-planar imaging (EPI) sequences are currently the most commonly used sequences for diffusion-weighted imaging (DWI) and functional magnetic resonance imaging (fMRI) as they allow relatively high signal to noise with rapid acquisition time. A major drawback of EPI is the substantial geometric distortion and signal loss that can occur due to magnetic field inhomogeneities close to air-tissue boundaries. If DWI-based tractography and fMRI are to be applied to these regions, then the distortions must be accurately corrected to achieve meaningful results. We describe robust acquisition and processing methods for correcting such distortions in spin echo (SE) EPI using a variant of the reversed direction k space traversal method with a number of novel additions. We demonstrate that dual direction k space traversal with maintained diffusion-encoding gradient strength and direction results in correction of the great majority of eddy current-associated distortions in DWI, in addition to those created by variations in magnetic susceptibility. We also provide examples to demonstrate that the presence of severe distortions cannot be ignored if meaningful tractography results are desired. The distortion correction routine was applied to SE-EPI fMRI acquisitions and allowed detection of activation in the temporal lobe that had been previously found using PET but not conventional fMRI. © 2010 Wiley-Liss, Inc.

  2. Paranasal sinuses and nasopharynx CT and MRI.

    PubMed

    Sievers, K W; Greess, H; Baum, U; Dobritz, M; Lenz, M

    2000-03-01

    Neoplastic disease of the nose, paranasal sinuses, the nasopharynx and the parapharyngeal space requires thorough assessment of location and extent in order to plan appropriate treatment. CT allows the deep soft tissue planes to be evaluated and provides a complement to the physical examination. It is especially helpful in regions involving thin bony structures (paranasal sinuses, orbita); here CT performs better than MRI. MRI possesses many advantages over other imaging modalities caused by its excellent tissue contrast. In evaluating regions involving predominantly soft tissue structures (ec nasopharynx and parapharyngeal space) MRI is superior to CT. The possibility to obtain strictly consecutive volume data sets with spiral CT or 3D MRI offer excellent perspectives to visualize the data via 2D or 3D postprocessing. Because head and neck tumors reside in a complex area, having a 3D model of the anatomical features may assist in the delineation of pathology. Data sets may be transferred directly into computer systems and thus be used in computer assisted surgery.

  3. 36 CFR 1275.64 - Reproduction of tape recordings of Presidential conversations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 3 2011-07-01 2011-07-01 false Reproduction of tape... § 1275.64 Reproduction of tape recordings of Presidential conversations. (a) To ensure the preservation... locations established by the Archivist in accordance with § 1275.62. (d) The reproduction for members of the...

  4. 36 CFR 1275.64 - Reproduction of tape recordings of Presidential conversations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Reproduction of tape... § 1275.64 Reproduction of tape recordings of Presidential conversations. (a) To ensure the preservation... locations established by the Archivist in accordance with § 1275.62. (d) The reproduction for members of the...

  5. Beyond Learning and Persona: Extending the Scope of Presidential Debate Effects.

    ERIC Educational Resources Information Center

    Benoit, William L.; McKinney, Mitchell S.; Holbert, R. Lance

    2001-01-01

    Uses a pretest/posttest design to assess more subtle effects of watching a 2000 presidential debate on attitudes and vote intention among undergraduate students. Notes that leadership and overall policy stance became more important factors in vote choice after watching the debate. Demonstrates a variety of potentially important effects of watching…

  6. Phlebitis, pulmonary emboli and presidential politics: Richard M. Nixon's complicated deep vein thrombosis.

    PubMed

    Pascarella, Luigi; Pappas, Theodore N

    2013-02-01

    In September of 1974, Richard Nixon resigned the Presidency of the United States during an impeachment investigation concerning the Watergate Affair. One month after his resignation, the former President had an exacerbation of his chronic deep vein thrombosis. He also received a Presidential pardon from Gerald Ford on the same day that his recurrent deep vein thrombosis was diagnosed. The political, legal, and medical events that unfolded in the fall of 1974 are the substance of this report. Presidents often receive medical care that stretches the ordinary as a result of their position and the importance of their actions. The events surrounding Richard Nixon's care for deep vein thrombosis and its complications were not unusual for Presidential health care but were closely intertwined with the legal proceedings during the prosecution of the Watergate defendants.

  7. A Sparse Bayesian Learning Algorithm for White Matter Parameter Estimation from Compressed Multi-shell Diffusion MRI.

    PubMed

    Pisharady, Pramod Kumar; Sotiropoulos, Stamatios N; Sapiro, Guillermo; Lenglet, Christophe

    2017-09-01

    We propose a sparse Bayesian learning algorithm for improved estimation of white matter fiber parameters from compressed (under-sampled q-space) multi-shell diffusion MRI data. The multi-shell data is represented in a dictionary form using a non-monoexponential decay model of diffusion, based on continuous gamma distribution of diffusivities. The fiber volume fractions with predefined orientations, which are the unknown parameters, form the dictionary weights. These unknown parameters are estimated with a linear un-mixing framework, using a sparse Bayesian learning algorithm. A localized learning of hyperparameters at each voxel and for each possible fiber orientations improves the parameter estimation. Our experiments using synthetic data from the ISBI 2012 HARDI reconstruction challenge and in-vivo data from the Human Connectome Project demonstrate the improvements.

  8. Assaults on Days of Campaign Rallies During the 2016 US Presidential Election.

    PubMed

    Morrison, Christopher N; Ukert, Benjamin; Palumbo, Aimee; Dong, Beidi; Jacoby, Sara F; Wiebe, Douglas J

    2018-07-01

    This study investigates whether assault frequency increased on days and in cities where candidates Donald Trump and Hillary Clinton held campaign rallies prior to the 2016 US Presidential election. We calculated city-level counts of police-reported assaults for 31 rallies for Donald Trump and 38 rallies for Hillary Clinton. Negative binomial models estimated the assault incidence on rally days (day 0) relative to that on eight control days for the same city (days -28, -21, -14, -7, +7, +14, +21, and +28). Cities experienced an increase in assaults (incidence rate ratio [IRR] = 1.12, 95% CI: 1.03-1.22) on the days of Donald Trump's rallies, and no change in assaults on the days of Hillary Clinton's rallies (IRR = 1.00; 95% CI: 0.94-1.06). Assaults increased on days when cities hosted Donald Trump's rallies during the 2016 Presidential election campaign.

  9. Just War Theory and Presidential Discourse Prior to Conflict

    DTIC Science & Technology

    2014-12-04

    Case for Combat , Edward J. Lordan lists last resort as a theme, among others, that has been used to persuade Americans to enter conflicts from the...Topic This paper studies the public statements of US presidents to ascertain justifications for war or armed intervention. Edward J. Lordan used a...similar approach in his book The Case for Combat : How Presidents Persuade Americans to go to War. In it, he examines presidential messaging and the

  10. A Qualitative Case Study of Hurricane Katrina and University Presidential Leadership

    ERIC Educational Resources Information Center

    McNeely, Stanton Francis, III

    2013-01-01

    Leaders of many institutions of higher education are not equipped to manage a major crisis or disaster, and presidential leadership during a disaster is essential, as university presidents are ultimately accountable for the well-being of their institutions. Hurricane Katrina devastated New Orleans in 2005, flooding 80% of the city for many weeks…

  11. The Gender Gap and Women's Issues in the 1988 Presidential Campaign.

    ERIC Educational Resources Information Center

    Nelson, Victoria

    Two factors during the 1988 presidential campaign were largely responsible for the erosion of "women's issues" and the so-called "gender gap"--the perception that a candidate is unattractive to women voters. This perception is thought to be based upon the candidate's stand on issues such as abortion, day care and the Equal…

  12. Radio Electioneering in the American Presidential Campaigns of 1932 and 1936.

    ERIC Educational Resources Information Center

    Nicolaides, Becky M.

    1988-01-01

    Presents a study which focuses on the use of network radio in the presidential campaigns of 1932 and 1936. Discusses the use of performance skills and sales techniques in broadcasts made by the Democrats and Republicans over the two major networks: the Columbia Broadcasting System and the National Broadcasting System. Examines how radio…

  13. Effects of Presidential Debate Watching and Ideology on Attitudes and Knowledge.

    ERIC Educational Resources Information Center

    Benoit, William L.; Webber, David J.; Berman, Julie

    1998-01-01

    Compares respondents who watched the first 1996 presidential debate with respondents who did not. Finds (1) those who watched the debate could more accurately recognize issue positions of Clinton and Dole than nonwatchers; (2) differences in the groups' assessment of character traits of the leading candidates; and (3) more respondents gave policy…

  14. Teaching the Presidential Elections Using Media Literacy in the LD Classroom

    ERIC Educational Resources Information Center

    Siegel, Jaclyn Kahn

    2017-01-01

    This paper examines how an educator at a school for students with learning disabilities (LD) used various types of media to engage her students, to develop their academic and executive functioning skills, and to heighten their awareness of media literacy and the 2012 and 2106 Presidential elections. Teacher-created curriculum materials and…

  15. Safe Heavens: Military Strategy and Space Sanctuary Thought

    DTIC Science & Technology

    1997-06-01

    November 1957, his service proposed two ASAT solutions: a modified Nike Zeus antiballistic missile and a “homing satellite” carrying a destructive charge.18...May 1962, Secretary of Defense (SECDEF) McNamara ordered the Army to modify the Nike Zeus antiballistic missile for a future ASAT role. The modified...would never become operational. President Carter’s 1978 Presidential Directive on Space Policy stated: The United States finds itself under increasing

  16. 75 FR 10229 - Application for Presidential Permit; Champlain Hudson Power Express, Inc.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-05

    .... electric power supply system under normal and contingency conditions, and any other factors that DOE may... Power Express, Inc. AGENCY: Office of Electricity Delivery and Energy Reliability, DOE. ACTION: Notice of application. SUMMARY: Champlain Hudson Power Express, Inc. (CHPEI) has applied for a Presidential...

  17. MO-FG-BRB-00: AAPM Presidential Debate [medical physics education

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    Building on the energy and excitement of Washington DC in a presidential election year, AAPM will host its own Presidential Debate to better understand the views of the AAPM membership! Past presidents of the AAPM, Drs. Bayouth, Hazle, Herman, and Seibert, will debate hot topics in medical physics including issues facing education, professional practice, and the advancement of science. The moderators, Drs. Brock and Stern, will also draw in topics from Point-Counterpoint articles from the Medical Physics Journals. Wrapping up the debate, the audience will have the opportunity to question the candidates in a town hall format. At the conclusionmore » of this lively debate, the winner will be decided by the audience, so bring your Audience Response Units! Be part of Medical Physics - Decision 2016! Learning Objectives: Understand AAPM members’ views and opinions on issues facing medical physics education Learn AAPM members’ views and opinions on issues facing professional practice Identify AAPM members’ view and opinions on issues facing the advancement of science in medical physics J. Bayouth, Funding support from NCI;Scientific Advisory Board member - ViewRay.« less

  18. TU-AB-BRA-09: A Novel Method of Generating Ultrafast Volumetric Cine MRI (VC-MRI) Using Prior 4D-MRI and On-Board Phase-Skipped Encoding Acquisition for Radiotherapy Target Localization

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang, C; Yin, F; Harris, W

    Purpose: To develop a technique generating ultrafast on-board VC-MRI using prior 4D-MRI and on-board phase-skipped encoding k-space acquisition for real-time 3D target tracking of liver and lung radiotherapy. Methods: The end-of-expiration (EOE) volume in 4D-MRI acquired during the simulation was selected as the prior volume. 3 major respiratory deformation patterns were extracted through the principal component analysis of the deformation field maps (DFMs) generated between EOE and all other phases. The on-board VC-MRI at each instant was considered as a deformation of the prior volume, and the deformation was modeled as a linear combination of the extracted 3 major deformationmore » patterns. To solve the weighting coefficients of the 3 major patterns, a 2D slice was extracted from VC-MRI volume to match with the 2D on-board sampling data, which was generated by 8-fold phase skipped-encoding k-space acquisition (i.e., sample 1 phase-encoding line out of every 8 lines) to achieve an ultrafast 16–24 volumes/s frame rate. The method was evaluated using XCAT digital phantom to simulate lung cancer patients. The 3D volume of end-ofinhalation (EOI) phase at the treatment day was used as ground-truth onboard VC-MRI with simulated changes in 1) breathing amplitude and 2) breathing amplitude/phase change from the simulation day. A liver cancer patient case was evaluated for in-vivo feasibility demonstration. Results: The comparison between ground truth and estimated on-board VC-MRI shows good agreements. In XCAT study with changed breathing amplitude, the volume-percent-difference(VPD) between ground-truth and estimated tumor volumes at EOI was 6.28% and the Center-of-Mass-Shift(COMS) was 0.82mm; with changed breathing amplitude and phase, the VPD was 8.50% and the COMS was 0.54mm. The study of liver patient case also demonstrated a promising in vivo feasibility of the proposed method Conclusion: Preliminary results suggest the feasibility to estimate ultrafast VC-MRI

  19. Phase space quantum mechanics - Direct

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nasiri, S.; Sobouti, Y.; Taati, F.

    2006-09-15

    Conventional approach to quantum mechanics in phase space (q,p), is to take the operator based quantum mechanics of Schroedinger, or an equivalent, and assign a c-number function in phase space to it. We propose to begin with a higher level of abstraction, in which the independence and the symmetric role of q and p is maintained throughout, and at once arrive at phase space state functions. Upon reduction to the q- or p-space the proposed formalism gives the conventional quantum mechanics, however, with a definite rule for ordering of factors of noncommuting observables. Further conceptual and practical merits of themore » formalism are demonstrated throughout the text.« less

  20. From Latifundia to Central Planning and Onward to Agribusiness: A Rejoinder to Joachim Singelmann's Presidential Address on "From Central Planning to Markets"

    ERIC Educational Resources Information Center

    Szelenyi, Ivan

    2011-01-01

    This article presents the author's rejoinder to Joachim Singelmann's presidential address on "From Central Planning to Markets." Joachim Singelmann in his presidential address challenged the received wisdom: socialism was doomed to fail; during the market transition all of its basic institutions had to be abolished and replaced by the…