Astronauts Brent Jett and Koichi Wakata work with Protein Crystal Growth experiment

NASA Image and Video Library

1996-01-20

STS072-310-007 (11-20 Jan. 1996) --- Astronauts Brent W. Jett Jr. (left) and Koichi Wakata work with the Protein Crystal Growth (PCG) experiment at the Single Locker Thermal Enclosure System (STES) on the Space Shuttle Endeavour’s mid-deck. Jett, making his first flight in space, served as the crew’s pilot, while Wakata served as a mission specialist. Wakata, also a first time Shuttle crew member, represents Japan’s National Space Development Agency (NASDA).

Elinor M. Brent-Dyer's Chalet School Series: Literature as an Historical Source

ERIC Educational Resources Information Center

Lidbury, Clare

2013-01-01

This article examines whether Elinor M. Brent-Dyer's Chalet School books--a series of girls' school stories spanning the late 1920s to the early 1970s--can be regarded as historical sources for the study of physical education and dance in girls' boarding schools during this period. An overview of her experience as teacher and…

Fidelity and breeding probability related to population density and individual quality in black brent geese Branta bernicla nigricans

USGS Publications Warehouse

Sedinger, J.S.; Chelgren, N.D.; Ward, D.H.; Lindberg, M.S.

2008-01-01

1. Patterns of temporary emigration (associated with non-breeding) are important components of variation in individual quality. Permanent emigration from the natal area has important implications for both individual fitness and local population dynamics. 2. We estimated both permanent and temporary emigration of black brent geese (Branta bernicla nigricans Lawrence) from the Tutakoke River colony, using observations of marked brent geese on breeding and wintering areas, and recoveries of ringed individuals by hunters. We used the likelihood developed by Lindberg, Kendall, Hines & Anderson 2001 (Combining band recovery data and Pollock's robust design to model temporary and permanent emigration. Biometrics, 57, 273-281) to assess hypotheses and estimate parameters. 3. Temporary emigration (the converse of breeding) varied among age classes up to age 5, and differed between individuals that bred in the previous years vs. those that did not. Consistent with the hypothesis of variation in individual quality, individuals with a higher probability of breeding in one year also had a higher probability of breeding the next year. 4. Natal fidelity of females ranged from 0.70 ?? 0.07-0.96 ?? 0.18 and averaged 0.83. In contrast to Lindberg et al. (1998), we did not detect a relationship between fidelity and local population density. Natal fidelity was negatively correlated with first-year survival, suggesting that competition among individuals of the same age for breeding territories influenced dispersal. Once females nested at the Tutakoke River, colony breeding fidelity was 1.0. 5. Our analyses show substantial variation in individual quality associated with fitness, which other analyses suggest is strongly influenced by early environment. Our analyses also suggest substantial interchange among breeding colonies of brent geese, as first shown by Lindberg et al. (1998).

Tractable flux-driven temperature, density, and rotation profile evolution with the quasilinear gyrokinetic transport model QuaLiKiz

NASA Astrophysics Data System (ADS)

Citrin, J.; Bourdelle, C.; Casson, F. J.; Angioni, C.; Bonanomi, N.; Camenen, Y.; Garbet, X.; Garzotti, L.; Görler, T.; Gürcan, O.; Koechl, F.; Imbeaux, F.; Linder, O.; van de Plassche, K.; Strand, P.; Szepesi, G.; Contributors, JET

2017-12-01

Quasilinear turbulent transport models are a successful tool for prediction of core tokamak plasma profiles in many regimes. Their success hinges on the reproduction of local nonlinear gyrokinetic fluxes. We focus on significant progress in the quasilinear gyrokinetic transport model QuaLiKiz (Bourdelle et al 2016 Plasma Phys. Control. Fusion 58 014036), which employs an approximated solution of the mode structures to significantly speed up computation time compared to full linear gyrokinetic solvers. Optimisation of the dispersion relation solution algorithm within integrated modelling applications leads to flux calculations × {10}6-7 faster than local nonlinear simulations. This allows tractable simulation of flux-driven dynamic profile evolution including all transport channels: ion and electron heat, main particles, impurities, and momentum. Furthermore, QuaLiKiz now includes the impact of rotation and temperature anisotropy induced poloidal asymmetry on heavy impurity transport, important for W-transport applications. Application within the JETTO integrated modelling code results in 1 s of JET plasma simulation within 10 h using 10 CPUs. Simultaneous predictions of core density, temperature, and toroidal rotation profiles for both JET hybrid and baseline experiments are presented, covering both ion and electron turbulence scales. The simulations are successfully compared to measured profiles, with agreement mostly in the 5%-25% range according to standard figures of merit. QuaLiKiz is now open source and available at www.qualikiz.com.

Parity violation constraints using cosmic microwave background polarization spectra from 2006 and 2007 observations by the QUaD polarimeter.

PubMed

Wu, E Y S; Ade, P; Bock, J; Bowden, M; Brown, M L; Cahill, G; Castro, P G; Church, S; Culverhouse, T; Friedman, R B; Ganga, K; Gear, W K; Gupta, S; Hinderks, J; Kovac, J; Lange, A E; Leitch, E; Melhuish, S J; Memari, Y; Murphy, J A; Orlando, A; Piccirillo, L; Pryke, C; Rajguru, N; Rusholme, B; Schwarz, R; O'Sullivan, C; Taylor, A N; Thompson, K L; Turner, A H; Zemcov, M

2009-04-24

We constrain parity-violating interactions to the surface of last scattering using spectra from the QUaD experiment's second and third seasons of observations by searching for a possible systematic rotation of the polarization directions of cosmic microwave background photons. We measure the rotation angle due to such a possible "cosmological birefringence" to be 0.55 degrees +/-0.82 degrees (random) +/-0.5 degrees (systematic) using QUaD's 100 and 150 GHz temperature-curl and gradient-curl spectra over the spectra over the multipole range 200

Variability of tidal signals in the Brent Delta Front: New observations on the Rannoch Formation, northern North Sea

NASA Astrophysics Data System (ADS)

Wei, Xiaojie; Steel, Ronald J.; Ravnås, Rodmar; Jiang, Zaixing; Olariu, Cornel; Li, Zhiyang

2016-04-01

Detailed observations on the Rannoch Formation in several deep Viking Graben wells indicate that the 'classical' wave-dominated Brent delta-front shows coupled storm-tide processes. The tidal signals are of three types: I): alternations of thick cross-laminated sandstone and thin mud-draped sandstone, whereby double mud drapes are prominent but discretely distributed, II): a few tidal bundles within bottomsets and foresets of up to 10 cm-thick sets cross-strata, and III): dm-thick heterolithic lamination showing multiple, well-organized sand-mud couplets. During progradation of the Brent Delta, the Rannoch shoreline system passed upward from 1) a succession dominated by clean-water, storm-event sets and cosets frequently and preferentially interbedded with type I tidal beds, and occasional types II and III tidal deposits, toward 2) very clean storm-event beds less frequently separated by types II and III tidal beds, and then into 3) a thin interval showing muddier storm-event beds mainly alternating with type II tidal beds. It is likely that those variations in preservation bias of storm and tidal beds in each facies succession result from combined effects of 1) the frequency and duration of storms; 2) river discharge; and 3) the absolute and relative strength of tides. Tidal deposits are interpreted as inter-storm, fair-weather deposits, occurred preferentially in longer intermittent fair-weather condition and periods of lower river discharge, and well-pronounced in the distal-reach of delta-front. The formation and preservation of tidal signals between storm beds, indicate that the studied Rannoch Formation was most likely a storm-dominated, tide-influenced delta front 1) near the mouth of a large Brent river, where a significant tidal prism and high tidal range might be expected, and 2) in a setting where there were relatively high sedimentation rates associated with high local subsidence rates, so that the storm waves did not completely rework the inter

The Quantitative Reasoning for College Science (QuaRCS) Assessment: Emerging Themes from 5 Years of Data

NASA Astrophysics Data System (ADS)

Follette, Katherine; Dokter, Erin; Buxner, Sanlyn

2018-01-01

The Quantitative Reasoning for College Science (QuaRCS) Assessment is a validated assessment instrument that was designed to measure changes in students' quantitative reasoning skills, attitudes toward mathematics, and ability to accurately assess their own quantitative abilities. It has been administered to more than 5,000 students at a variety of institutions at the start and end of a semester of general education college science instruction. I will begin by briefly summarizing our published work surrounding validation of the instrument and identification of underlying attitudinal factors (composite variables identified via factor analysis) that predict 50% of the variation in students' scores on the assessment. I will then discuss more recent unpublished work, including: (1) Development and validation of an abbreviated version of the assessment (The QuaRCS Light), which results in marked improvements in students' ability to maintain a high effort level throughout the assessment and has broad implications for quantitative reasoning assessments in general, and (2) Our efforts to revise the attitudinal portion of the assessment to better assess math anxiety level, another key factor in student performance on numerical assessments.

Investigation into the suitability and accessibility of catering practices to inpatients from minority ethnic groups in Brent.

PubMed

Hartley, Becky A; Hamid, F

2002-06-01

The Borough of Brent has one of the largest ethnic minority populations in England, with a growing number of refugee communities from Africa and Europe. Two important issues to be considered when developing culturally sensitive services in the hospital (including food provision) are that practices meet the religious and cultural requirements of the population that the hospital serves and that staff are equipped with the skills to understand cultural differences in illness and treatment. To review accessibility and suitability of multicultural meals to minority ethnic communities across five hospital sites in Brent and determine the level of nursing staff knowledge of multicultural dietary competencies. One survey was completed in each of the five hospital sites to gather information about current catering practices. Two separate questionnaires obtained information of the level of inpatient satisfaction with multicultural meals amongst Hindu, Muslim, Caribbean and Jewish patient groups and knowledge of nursing staff about multicultural competencies. Community groups representing minority ethnic populations participated in focus groups to establish feedback about dietary requirements in hospitals. Access to multicultural meals varied across hospital sites. Of 98 patients in the inpatient satisfaction survey, 74% were aware of the availability of multicultural meals with 51% of these patients not ordering any of the Asian vegetarian, Asian halal, Caribbean or kosher meals, citing satisfaction with European food as the main reason. Those ordering multicultural meals reported satisfaction most of the time (42%), satisfied most of the time (38%) and never satisfied (19%). The African Muslim group was the least satisfied with current halal meal provision. Forty-seven per cent of nurses questioned could accurately answer questions about multicultural dietary competencies. Improvements could be made to improve accessibility and improve suitability of meal choices to

Comment on Brent Beal's and Heather Olson Beal's "Rethinking the Market Metaphor: School Choice, the Common Good, and the National Football League"

ERIC Educational Resources Information Center

Bast, Joseph L.

2013-01-01

In their article "Rethinking the Market Metaphor: School Choice, the Common Good, and the National Football League," Brent D. Beal and Heather K. Olson Beal (this issue) promise to update some of the arguments made by Jeffrey R. Henig (1994) and add an interesting twist by proposing the National Football League (NFL) as a possible…

Emotional intelligence: the Sine Qua Non for a clinical leadership toolbox.

PubMed

Rao, Paul R

2006-01-01

Over the past decade, it has become increasingly clear that although IQ and technical skills are important, emotional intelligence is the Sine Qua Non of leadership. According to Goleman [Goleman, D. (1998). What makes a leader? Harvard Business Review, 93-102] "effective leaders are alike in one crucial way: they all have a high degree of emotional intelligence...and can also be linked to strong performance." The original five dimensions of EIQ are described and applied to both supervisory and clinical scenarios. As a result of reading this work, you will be able to: (1) define and provide an illustration of each of the five components of emotional intelligence (EIQ); (2) outline the relationship of EIQ to success in your profession and your personal life; (3) create a strategic action plan to enhance each dimension of EIQ in your daily life; (4) list at least three real-life experiences that could have resulted a favorable outcome with an improved EIQ; (5) complete a self-evaluation of your EIQ.

Quantitative structure-activity relationships of selective antagonists of glucagon receptor using QuaSAR descriptors.

PubMed

Manoj Kumar, Palanivelu; Karthikeyan, Chandrabose; Hari Narayana Moorthy, Narayana Subbiah; Trivedi, Piyush

2006-11-01

In the present paper, quantitative structure activity relationship (QSAR) approach was applied to understand the affinity and selectivity of a novel series of triaryl imidazole derivatives towards glucagon receptor. Statistically significant and highly predictive QSARs were derived for glucagon receptor inhibition by triaryl imidazoles using QuaSAR descriptors of molecular operating environment (MOE) employing computer-assisted multiple regression procedure. The generated QSAR models revealed that factors related to hydrophobicity, molecular shape and geometry predominantly influences glucagon receptor binding affinity of the triaryl imidazoles indicating the relevance of shape specific steric interactions between the molecule and the receptor. Further, QSAR models formulated for selective inhibition of glucagon receptor over p38 mitogen activated protein (MAP) kinase of the compounds in the series highlights that the same structural features, which influence the glucagon receptor affinity, also contribute to their selective inhibition.

The OSU1/QUA2/TSD2-Encoded Putative Methyltransferase Is a Critical Modulator of Carbon and Nitrogen Nutrient Balance Response in Arabidopsis

PubMed Central

Zheng, Zhi-Liang

2008-01-01

The balance between carbon (C) and nitrogen (N) nutrients must be tightly coordinated so that cells can optimize their opportunity for metabolism, growth and development. However, the C and N nutrient balance perception and signaling mechanism remains poorly understood. Here, we report the isolation and characterization of two allelic oversensitive to sugar1 mutants (osu1-1, osu1-2) in Arabidopsis thaliana. Using the cotyledon anthocyanin accumulation and root growth inhibition assays, we show that the osu1 mutants are more sensitive than wild-type to both of the imbalanced C/N conditions, high C/low N and low C/high N. However, under the balanced C/N conditions (low C/low N or high C/high N), the osu1 mutants have similar anthocyanin levels and root lengths as wild-type. Consistently, the genes encoding two MYB transcription factors (MYB75 and MYB90) and an Asn synthetase isoform (ASN1) are strongly up-regulated by the OSU1 mutation in response to high C/low N and low C/high N, respectively. Furthermore, the enhanced sensitivity of osu1-1 to high C/low N with respect to anthocyanin accumulation but not root growth inhibition can be suppressed by co-suppression of MYB75, indicating that MYB75 acts downstream of OSU1 in the high C/low N imbalance response. Map-based cloning reveals that OSU1 encodes a member of a large family of putative methyltransferases and is allelic to the recently reported QUA2/TSD2 locus identified in genetic screens for cell-adhesion-defective mutants. Accumulation of OSU1/QUA2/TSD2 transcript was not regulated by C and N balance, but the OSU1 promoter was slightly more active in the vascular system. Taken together, our results show that the OSU1/QUA2/TSD2-encoded putative methyltransferase is required for normal C/N nutrient balance response in plants. PMID:18167546

CHARACTERIZATION OF THE MILLIMETER-WAVE POLARIZATION OF CENTAURUS A WITH QUaD

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zemcov, M.; Bock, J.; Leitch, E.

2010-02-20

Centaurus (Cen) A represents one of the best candidates for an isolated, compact, highly polarized source that is bright at typical cosmic microwave background (CMB) experiment frequencies. We present measurements of the 4{sup 0} x 2{sup 0} region centered on Cen A with QUaD, a CMB polarimeter whose absolute polarization angle is known to an accuracy of 0.{sup 0}5. Simulations are performed to assess the effect of misestimation of the instrumental parameters on the final measurement and systematic errors due to the field's background structure and temporal variability from Cen A's nuclear region are determined. The total (Q, U) ofmore » the inner lobe region is (1.00 +- 0.07(stat.) +- 0.04(sys.), - 1.72 +- 0.06 +- 0.05) Jy at 100 GHz and (0.80 +- 0.06 +- 0.06, - 1.40 +- 0.07 +- 0.08) Jy at 150 GHz, leading to polarization angles and total errors of -30.{sup 0}0 +- 1.{sup 0}1 and -29.{sup 0}1 +- 1.{sup 0}7. These measurements will allow the use of Cen A as a polarized calibration source for future millimeter experiments.« less

Does evidence influence policy? Resource allocation and the Indigenous Burden of Disease study.

PubMed

Doran, Christopher M; Ling, Rod; Searles, Andrew; Hill, Peter

2016-01-01

Objective The Indigenous Burden of Disease (IBoD) report is the most comprehensive assessment of Indigenous disease burden in Australia. The aim of the present study was to investigate the potential effect of the IBoD report on Australian Indigenous health policy, service expenditure and research funding. Findings have significance for understanding factors that may influence Indigenous health policy. Methods The potential effect of the IBoD report was considered by: (1) conducting a text search of pertinent documents published by the federal government, Council of Australian Governments and the National Health and Medical Research Council of Australia (NHMRC) and observing the quantity and quality of references to IBoD; (2) examining data on government Indigenous healthcare expenditure for trends consistent with the findings and policy implications of the IBoD report; and (3) examining NHMRC Indigenous grant allocation trends consistent with the findings and policy implications of the IBoD report. Results Of 110 government and NHMRC documents found, IBoD was cited in 27. Immediately after publication of the IBoD report, federal and state governments increased Indigenous health spending (relative to non-Indigenous), notably for community health and public health at the state level. Expenditure on Indigenous hospital separations for chronic diseases also increased. These changes are broadly consistent with the findings of the IBoD report on the significance of chronic disease and the need to address certain risk factors. However, there is no evidence that such changes had a causal connection with the IBoD study. After publication of the IBoD report, changes in NHMRC Indigenous research funding showed little consistency with the findings of the IBoD report. Conclusions The present study found only indirect and inconsistent correlational evidence of the potential influence of the IBoD report on Indigenous health expenditure and research funding. Further assessment of

Ibogaine attenuation of morphine withdrawal in mice: role of glutamate N-methyl-D-aspartate receptors.

PubMed

Leal, Mirna Bainy; Michelin, Kátia; Souza, Diogo Onofre; Elisabetsky, Elaine

2003-08-01

Ibogaine (IBO) is an alkaloid with putative antiaddictive properties, alleviating opiates dependence and withdrawal. The glutamate N-methyl-D-aspartate (NMDA) receptors have been implicated in the physiological basis of drug addiction; accordingly, IBO acts as a noncompetitive NMDA antagonist. The purpose of this study was to evaluate the effects of IBO on naloxone-induced withdrawal syndrome in morphine-dependent mice, focusing on the role of NMDA receptors. Jumping, a major behavioral expression of such withdrawal, was significantly (P<.01) inhibited by IBO (40 and 80 mg/kg, 64.2% and 96.9% inhibition, respectively) and MK-801 (0.15 and 0.30 mg/kg, 67.3% and 97.7%, respectively) given prior to naloxone. Coadministration of the lower doses of IBO (40 mg/kg) and MK-801 (0.15 mg/kg) results in 94.7% inhibition of jumping, comparable to the effects of higher doses of either IBO or MK-801. IBO and MK-801 also significantly inhibited NMDA-induced (99.0% and 71.0%, respectively) jumping when given 30 min (but not 24 h) prior to NMDA in nonaddictive mice. There were no significant differences in [3H]MK-801 binding to cortical membranes from naive animals, morphine-dependent animals, or morphine-dependent animals treated with IBO or MK-801. This study provides further evidence that IBO does have an inhibitory effect on opiate withdrawal symptoms and suggests that the complex process resulting in morphine withdrawal includes an IBO-sensitive functional and transitory alteration of NMDA receptor.

A review of social housing regeneration in the London Borough of Brent.

PubMed

Stewart, J; Rhoden, M

2003-03-01

Council high-rise estates sprang up rapidly during the 1960s and 1970s, with cross-governmental support to resolve the nation's housing crisis. It soon became apparent that many such new estates, designed by remote architects, and sometimes constructed rapidly and unsatisfactorily, did not provide the ideal living initially perceived. Many estates had early problems with architecture, construction and design. They proved an inhumane environment for many residents and there were frequent problems with communal features. Such estates were soon stigmatised and difficult to let as increasingly residual households were placed there, creating majority welfare-dependent estates. This created a downward spiral that traditional, and remote, housing management found difficult to address, and was too wide-scale to rectify financially within existing regimes. Prior to the 1980s, there were no specific government policies to tackle housing regeneration on high-rise estates. Problems became wider than traditional housing management and poor housing environments, encompassing social and economic exclusion. This paper, based on historical and contemporary literature as well as estate visits, reviews regeneration policy in three council housing estates within the London Borough of Brent. It traces successive government approaches since the 1980s from one that challenged the very status of council housing--notably at Stonebridge Park and Chalkhill, to one of partnership with the local authority--at South Kilburn. Housing policy is now concerned with more than just housing--it is about moving toward social inclusion, which requires initiative, flair, resource and commitment. It is about new accountabilities--not just numbers of bricks and mortar constructions, but about the lives, opportunities and health of those who live in an area. This fundamentally involves a partnership approach with residents at the centre of regeneration. This paper finds that sustainable estate regeneration

Characterization of naturally developing small intestinal bacterial overgrowth in 16 German shepherd dogs.

PubMed

Willard, M D; Simpson, R B; Fossum, T W; Cohen, N D; Delles, E K; Kolp, D L; Carey, D P; Reinhart, G A

1994-04-15

Sixteen German Shepherd Dogs were found, via quantitative microbial culture of intestinal fluid samples, to have small intestinal bacterial overgrowth (IBO) over an 11-month period. All dogs were deficient in serum IgA. Consistent clinical signs suggestive of an alimentary tract disorder were not observed. Serum cobalamin determinations were not helpful in detecting IBO. Serum folate concentrations had variable sensitivity and specificity for detecting dogs from which we could culture > or = 1 x 10(5) bacterial/ml from intestinal fluid samples in the nonfed state. Histologic and intestinal mucosal cytologic examinations were not useful in detecting IBO. Substantial within-dog and between-dog variation was found in the numbers and species of bacteria in the intestines. The difficulty in diagnosing IBO, the variability in organisms found in individual dogs on repeated sampling, the likelihood that intestinal fluid microbial cultures failed to diagnose IBO in some dogs, and the potential of IBO to be clinically inapparent were the most important findings in this study.

Examining the Role of Numeracy in College STEM Courses: Results from the Quantitative Reasoning for College Science (QuaRCS) Assessment Instrument

NASA Astrophysics Data System (ADS)

Follette, Katherine B.; McCarthy, Donald W.; Dokter, Erin F.; Buxner, Sanlyn; Prather, Edward E.

2016-01-01

Is quantitative literacy a prerequisite for science literacy? Can students become discerning voters, savvy consumers and educated citizens without it? Should college science courses for nonmajors be focused on "science appreciation", or should they engage students in the messy quantitative realities of modern science? We will present results from the recently developed and validated Quantitative Reasoning for College Science (QuaRCS) Assessment, which probes both quantitative reasoning skills and attitudes toward mathematics. Based on data from nearly two thousand students enrolled in nineteen general education science courses, we show that students in these courses did not demonstrate significant skill or attitude improvements over the course of a single semester, but find encouraging evidence for longer term trends.

Midlife Hypertensive Status and Cognitive Function 20 Years Later: The Southall and Brent Revisited Study

PubMed Central

Taylor, Clare; Tillin, Therese; Chaturvedi, Nish; Dewey, Michael; Ferri, Cleusa P; Hughes, Alun; Prince, Martin; Richards, Marcus; Shah, Ajit; Stewart, Robert

2013-01-01

Objectives: To investigate long-term prospective associations between a range of measurements of hypertensive status in midlife and cognitive impairment 20 years later. Design: Cohort study. Setting: Two areas (Southall and Brent) of northwest London. Participants: Survey samples of a multiethnic population (European, African Caribbean, South Asian) aged 40 to 67 were followed up 20 years later. Measurements: Comprehensive cardiovascular assessments were performed at baseline, including measurements of resting blood pressure (BP) and, in a subsample, ambulatory BP. At follow-up, a battery of cognitive assessments was administered, and a composite outcome was derived, with impairment defined as the lowest 10% within each ethnic group. Logistic regression models were used to investigate associations with prior measures of hypertensive status. Results: In 1,484 participants at follow-up, cognitive impairment showed significant U-shaped associations with baseline diastolic BP (DBP) and mean arterial pressure (MAP; strongest for those aged ≥50 at baseline), independent of a range of covariates, but no associations were found with systolic BP or pulse pressure. Cognitive impairment was also associated with antihypertensive medication use and higher evening ambulatory DBP at baseline. No substantial differences in strengths of association were found between ethnic groups. Conclusion: Low and high DBP and MAP were associated with cognitive impairment 20 years later. Higher evening DBP on ambulatory monitoring was also associated with greater risk. PMID:24028355

The Ethics of Biomedical Big Data : Brent Daniel Mittelstadt and Luciano Floridi, eds. 2016, Springer International Publishing (Cham, Switzerland, 978-3-319-33523-0, 480 pp.).

PubMed

Mason, Paul H

2017-12-01

The availability of diverse sources of data related to health and illness from various types of modern communication technology presents the possibility of augmenting medical knowledge, clinical care, and the patient experience. New forms of data collection and analysis will undoubtedly transform epidemiology, public health, and clinical practice, but what ethical considerations come in to play? With a view to analysing the ethical and regulatory dimensions of burgeoning forms of biomedical big data, Brent Daniel Mittelstadt and Luciano Floridi have brought together thirty scholars in an edited volume that forms part of Springer's Law, Governance and Technology book series in a collection titled The Ethics of Biomedical Big Data. With eighteen chapters partitioned into six carefully devised sections, this volume engages with core theoretical, ethical, and regulatory challenges posed by biomedical big data.

Law and Literature: An African Example.

ERIC Educational Resources Information Center

Kendall, Diane S.

1981-01-01

Presents a learning activity in which secondary students read about and analyze the legal institutions of an African tribe called the Ibo. Students compare the Ibo's precolonial system of resolving disputes with the U.S. system. (AM)

An Array of Ice-Based Observatories for Arctic Studies

NASA Astrophysics Data System (ADS)

Plueddemann, A.; Proshutinsky, A.; Toole, J.; Ashjian, C.; Krishfield, R.; Carmack, E.; Dethloff, K.; Fahrbach, E.; Gascard, J.; Perovich, D.; Pryamikov, S.

2004-12-01

The Arctic Ocean's role in global climate - while now widely appreciated - remains poorly understood. Lack of information about key processes within the oceanic, cryospheric, biologic, atmospheric and geologic disciplines will continue to impede physical understanding, model validation, and climate prediction until a practical observing system is designed and implemented. Requirements, challenges and recommendations for Ice-Based Observatories (IBO?s) for the Arctic Ocean were formulated by workshop participants of an international workshop entitled "Arctic Observing Based on Ice-Tethered Platforms" held at the Woods Hole Oceanographic Institution in Woods Hole, Massachusetts, USA, June 28-30, 2004. The principal conclusion from the workshop was that practical, cost-effective and proven IBO designs presently exist, can be readily extended to provide interdisciplinary observations, and should be implemented expeditiously as part of a coordinated Arctic observing system. Ice-based instrument systems are a proven means of acquiring unattended high quality air, ice, and ocean data from the central Arctic during all seasons. Arctic Change is ongoing and measurements need to begin now. An array of approximately 25-30 IBO units maintained throughout the Arctic Ocean is envisioned to observe the annual and interannual variations of the polar atmosphere-ice-ocean environment. An international body will be required to coordinate the various national programs (eliminate overlap, insure no data holes) and insure compatibility of data and their widespread distribution. A long-term, internationally coordinated logistics plan should be implemented as an essential complement to scientific and technical plans for an IBO array. The 25 years of IABP drift trajectories, existing data climatologies and available numerical simulations should be exploited to derive insight to optimal array design, deployment strategies, sampling intervals, and expected performance of an IBO array. IBO

Effect of memantine on the levels of glial cells, neuropeptides, and peptide-degrading enzymes in rat brain regions of ibotenic acid-treated alzheimer's disease model.

PubMed

Ahmed, M M; Hoshino, H; Chikuma, T; Yamada, M; Kato, T

2004-01-01

It has been implicated that glia activation plays a critical role in the progression of Alzheimer's disease (AD). However, the precise mechanism of glia activation is not clearly understood yet. In our present studies, we confirmed our previous results where change the levels of neuropeptides and peptidases in ibotenic acid (IBO) infusion into the rat nucleus basalis magnocellularis, an animal model of AD. Furthermore, we extended our study to investigate a possible protection effect of co-administration on the changes of neuropeptides, and neuronal and glial cells in IBO-infused rat brain by memantine treatment. The levels of substance P and somatostatin were decreased in the striatum and frontal cortex 1 week after IBO infusion, and recovered to the control level by memantine treatment, indicating the involvement of neuropeptides in AD pathology. Furthermore, the immunohistochemical and enzymatic studies of GFAP and CD 11b, and peptidylarginine deiminase, markers of glia, in the striatum and frontal cortex showed the increase in IBO-treated rat brain as compared with controls, while co-administration of memantine and IBO no increase of astrocytes and microglia activation was observed. The present biochemical and immunohistochemical results suggest that glia activation might play an important role to the pathology of AD, and correlate with the changes of neuropeptide levels in AD brain that is recovered by memantine treatment.

Mainstreaming Disability in Education beyond 2015

ERIC Educational Resources Information Center

Sefotho, Maximus Monaheng

2015-01-01

This article presents an exemplary case study of an Independent Business Owner (IBO) from multiple case studies on narratives of differently abled persons. The aim of this article is to illustrate mainstreaming disability through an exemplary case of the IBO. The article is informed by the imperatives of critical theory to understand mainstreaming…

Ethnicity and fertility in Nigeria.

PubMed

Kollehlon, Konia T

2003-01-01

Using a sample of Hausa-Fulani, Yoruba, Ibo, and all other women from the 1990 Nigerian Demographic and Health Survey, this study examines ethnic fertility differentials in Nigeria within the context of the social characteristics and cultural hypotheses. Among all women, we find the net fertility of Hausa-Fulani women to be lower than that of Other women; with no statistically significant difference in the net fertility of Ibo, Yourba, and Other women. But, among currently married women, we find the net fertility of Hausa-Fulani and Yoruba women to be lower than that of Other women, while the net fertility of Ibo women is higher than that of Other women. Overall, the findings of this study are more consistent with the cultural hypothesis, because statistically significant fertility differentials by ethnicity remain, even after controlling for selected socioeconomic and demographic variables.

Chronic Glucocorticoids Increase Hippocampal Vulnerability to Neurotoxicity under Conditions That Produce CA3 Dendritic Retraction But Fail to Impair Spatial Recognition Memory

PubMed Central

Conrad, Cheryl D.; McLaughlin, Katie J.; Harman, James S.; Foltz, Cainan; Wieczorek, Lindsay; Lightner, Elizabeth; Wright, Ryan L.

2007-01-01

We previously found that chronic stress conditions producing CA3 dendritic retraction and spatial memory deficits make the hippocampus vulnerable to the neurotoxin ibotenic acid (IBO). The purpose of this study was to determine whether exposure to chronic corticosterone (CORT) under conditions that produce CA3 dendritic retraction would enhance CA3 susceptibility to IBO. Male Sprague Dawley rats were chronically treated for 21 d with CORT in drinking water (400 μg/ml), and half were given daily injections of phenytoin (40 mg/kg), an antiepileptic drug that prevents CA3 dendritic retraction. Three days after treatments stopped, IBO was infused into the CA3 region. Conditions producing CA3 dendritic retraction (CORT and vehicle) exacerbated IBO-induced CA3 damage compared with conditions in which CA3 dendritic retraction was not observed (vehicle and vehicle, vehicle and phenytoin, CORT and phenytoin). Additionally, spatial recognition memory was assessed using the Y-maze, revealing that conditions producing CA3 dendritic retraction failed to impair spatial recognition memory. Furthermore, CORT levels in response to a potentially mild stressor (injection and Y-maze exposure) stayed at basal levels and failed to differ among key groups (vehicle and vehicle, CORT and vehicle, CORT and phenytoin), supporting the interpretations that CORT levels were unlikely to have been elevated during IBO infusion and that the neuroprotective actions of phenytoin were not through CORT alterations. These data are the first to show that conditions with prolonged glucocorticoid elevations leading to structural changes in hippocampal dendritic arbors can make the hippocampus vulnerable to neurotoxic challenges. These findings have significance for many disorders with elevated glucocorticoids that include depression, schizophrenia, Alzheimer’s disease, and Cushing’s disease. PMID:17670974

Associations Between Left Ventricular Dysfunction and Brain Structure and Function: Findings From the SABRE (Southall and Brent Revisited) Study.

PubMed

Park, Chloe M; Williams, Emily D; Chaturvedi, Nish; Tillin, Therese; Stewart, Robert J; Richards, Marcus; Shibata, Dean; Mayet, Jamil; Hughes, Alun D

2017-04-18

Subclinical left ventricular (LV) dysfunction has been inconsistently associated with early cognitive impairment, and mechanistic pathways have been poorly considered. We investigated the cross-sectional relationship between LV dysfunction and structural/functional measures of the brain and explored the role of potential mechanisms. A total of 1338 individuals (69±6 years) from the Southall and Brent Revisited study underwent echocardiography for systolic (tissue Doppler imaging peak systolic wave) and diastolic (left atrial diameter) assessment. Cognitive function was assessed and total and hippocampal brain volumes were measured by magnetic resonance imaging. Global LV function was assessed by circulating N-terminal pro-brain natriuretic peptide. The role of potential mechanistic pathways of arterial stiffness, atherosclerosis, microvascular disease, and inflammation were explored. After adjusting for age, sex, and ethnicity, lower systolic function was associated with lower total brain (beta±standard error, 14.9±3.2 cm 3 ; P <0.0001) and hippocampal volumes (0.05±0.02 cm 3 , P =0.01). Reduced diastolic function was associated with poorer working memory (-0.21±0.07, P =0.004) and fluency scores (-0.18±0.08, P =0.02). Reduced global LV function was associated with smaller hippocampal volume (-0.10±0.03 cm 3 , P =0.004) and adverse visual memory (-0.076±0.03, P =0.02) and processing speed (0.063±0.02, P =0.006) scores. Separate adjustment for concomitant cardiovascular risk factors attenuated associations with hippocampal volume and fluency only. Further adjustment for the alternative pathways of microvascular disease or arterial stiffness attenuated the relationship between global LV function and visual memory. In a community-based sample of older people, measures of LV function were associated with structural/functional measures of the brain. These associations were not wholly explained by concomitant risk factors or potential mechanistic pathways. �

An assessment of the mechanical stability of wells offshore Nigeria

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lowrey, J.P.; Ottesen, S.

In 1991 lost time due to stuck pipe related drilling problems accounted for approximately 18% of total drilling time in Mobil Producing Nigeria Ultd.`s (MPN) offshore operations. The primary cause of stuck pipe was identified as mechanical wellbore instability. This paper presents an assessment of the mechanical stability of MPN`s wells offshore Nigeria. The objectives of the study were to: (1) determine the magnitude of the in-situ principal stresses and material properties of the troublesome Intra-Biafra and Qua Iboe shale sequences; (2) quantify the drilling fluid densities required to drill mechanically stable wells through these formations; (3) review and recommendmore » well planning and operational parameters which aid in minimizing wellbore stability-related drilling problems. The well-bore stability assessment was carried out with the aid of a 3-dimensional wellbore stability model using field derived data from the study area to corroborate the results. The collection and analysis of drilling data (borehole geometry and density logs, pore pressure, leak-off tests, local geology and other relevant well records) to determine the magnitude of the in-situ principal stresses, together with compressive strength tests on formation cores are discussed. Minimum safe drilling fluid densities to promote wellbore stability as a function of well geometry and depth are presented for the most troublesome shales drilled in the study area. Implementation of the results reduced wellbore stability related problems and associated trouble time to less than 5% in 1992.« less

View from the East: Arab Perceptions of United States Presence and Policy

DTIC Science & Technology

2003-02-01

View from the East: Arab Perceptions of United States Presence and Policy Brent J . Talbot and Michael B. Meyer INSS...IMPLICATIONS FOR US POLICY IN THE MIDDLE EAST, Brent J . Talbot Introduction 1 The Perception Problem 3 The Consensus Issue 11...THE ARAB PERCEPTION AND CONSENSUS PROBLEMS: IMPLICATIONS FOR US POLICY IN THE MIDDLE EAST, Brent J . Talbot EXECUTIVE SUMMARY This paper is a

Medawar's legacy to cellular immunology and clinical transplantation: a commentary on Billingham, Brent and Medawar (1956) 'Quantitative studies on tissue transplantation immunity. III. Actively acquired tolerance'.

PubMed

Simpson, Elizabeth

2015-04-19

'Quantitative studies on tissue transplantation immunity. III. Actively acquired tolerance', published in Philosophical Transactions B in 1956 by Peter Medawar and his colleagues, PhD graduate Leslie Brent and postdoctoral fellow Rupert Billingham, is a full description of the concept of acquired transplantation tolerance. Their 1953 Nature paper (Billingham RE et al. 1953 Nature 172, 603-606. (doi:10.1038/172603a0)) had provided initial evidence with experimental results from a small number of neonatal mice, with mention of similar findings in chicks. The Philosophical Transactions B 1956 paper is clothed with an astonishing amount of further experimental detail. It is written in Peter Medawar's landmark style: witty, perceptive and full of images that can be recalled even when details of the supporting information have faded. Those images are provided not just by a series of 20 colour plates showing skin graft recipient mice, rats, rabbits, chickens and duck, bearing fur or plumage of donor origin, but by his choice of metaphor, simile and analogy to express the questions being addressed and the interpretation of their results, along with those of relevant published data and his prescient ideas of what the results might portend. This work influenced both immunology researchers and clinicians and helped to lay the foundations for successful transplantation programmes. It led to the award of a Nobel prize in 1960 to Medawar, and subsequently to several scientists who advanced these areas. This commentary was written to celebrate the 350th anniversary of the journal Philosophical Transactions of the Royal Society.

A clade in the QUASIMODO2 family evolved with vascular plants and supports a role for cell wall composition in adaptation to environmental changes.

PubMed

Fuentes, Sara; Pires, Nuno; Østergaard, Lars

2010-08-01

The evolution of plant vascular tissue is tightly linked to the evolution of specialised cell walls. Mutations in the QUASIMODO2 (QUA2) gene from Arabidopsis thaliana were previously shown to result in cell adhesion defects due to reduced levels of the cell wall component homogalacturonic acid. In this study, we provide additional information about the role of QUA2 and its closest paralogues, QUASIMODO2 LIKE1 (QUL1) and QUL2. Within the extensive QUA2 family, our phylogenetic analysis shows that these three genes form a clade that evolved with vascular plants. Consistent with a possible role of this clade in vasculature development, QUA2 is highly expressed in the vascular tissue of embryos and inflorescence stems and overexpression of QUA2 resulted in temperature-sensitive xylem collapse. Moreover, in-depth characterisation of qua2 qul1 qul2 triple mutant and 35S::QUA2 overexpression plants revealed contrasting temperature-dependent stem development with dramatic effects on stem width. Taken together, our results suggest that the QUA2-specific clade contributed to the evolution of vasculature and illustrate the important role that modification of cell wall composition plays in the adaptation to changing environmental conditions, including changes in temperature.

Improvement of CD-SEM mark position measurement accuracy

NASA Astrophysics Data System (ADS)

Kasa, Kentaro; Fukuhara, Kazuya

2014-04-01

CD-SEM is now attracting attention as a tool that can accurately measure positional error of device patterns. However, the measurement accuracy can get worse due to pattern asymmetry as in the case of image based overlay (IBO) and diffraction based overlay (DBO). For IBO and DBO, a way of correcting the inaccuracy arising from measurement patterns was suggested. For CD-SEM, although a way of correcting CD bias was proposed, it has not been argued how to correct the inaccuracy arising from pattern asymmetry using CD-SEM. In this study we will propose how to quantify and correct the measurement inaccuracy affected by pattern asymmetry.

In Vivo Multimodal Imaging of NF-kappaB (pB) Spatial and Temporal Activation Following Light Injury in the Mouse Retina

DTIC Science & Technology

2014-01-15

Ginger M. Pocock Brent J. Lavey Human Effectiveness Directorate Directed Energy Bioeffects Division Optical Radiation Branch Adam Boretsky...FA8650-08-D-6930 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 0602202F 6. AUTHOR(S) Ginger M. Pocock, Brent J. Lavey, Adam Boretsky, Praveena Gupta

Diffraction-based overlay for spacer patterning and double patterning technology

NASA Astrophysics Data System (ADS)

Lee, Byoung Hoon; Park, JeongSu; Lee, Jongsu; Park, Sarohan; Lim, ChangMoon; Yim, Dong-Gyu; Park, Sungki; Ryu, Chan-Ho; Morgan, Stephen; van de Schaar, Maurits; Fuchs, Andreas; Bhattacharyya, Kaustuve

2011-03-01

Overlay performance will be increasingly important for Spacer Patterning Technology (SPT) and Double Patterning Technology (DPT) as various Resolution Enhancement Techniques are employed to extend the resolution limits of lithography. Continuous shrinkage of devices makes overlay accuracy one of the most critical issues while overlay performance is completely dependent on exposure tool. Image Based Overlay (IBO) has been used as the mainstream metrology for overlay by the main memory IC companies, but IBO is not suitable for some critical layers due to the poor Tool Induced Shift (TIS) values. Hence new overlay metrology is required to improve the overlay measurement accuracy. Diffraction Based Overlay (DBO) is regarded to be an alternative metrology to IBO for more accurate measurements and reduction of reading errors. Good overlay performances of DBO have been reported in many articles. However applying DBO for SPT and DPT layers poses extra challenges for target design. New vernier designs are considered for different DPT and SPT schemes to meet overlay target in DBO system. In this paper, we optimize the design of the DBO target and the performance of DBO to meet the overlay specification of sub-3x nm devices which are using SPT and DPT processes. We show that the appropriate vernier design yields excellent overlay performance in residual and TIS. The paper also demonstrated the effects of vernier structure on overlay accuracy from SEM analysis.

Reduction of image-based ADI-to-AEI overlay inconsistency with improved algorithm

NASA Astrophysics Data System (ADS)

Chen, Yen-Liang; Lin, Shu-Hong; Chen, Kai-Hsiung; Ke, Chih-Ming; Gau, Tsai-Sheng

2013-04-01

In image-based overlay (IBO) measurement, the measurement quality of various measurement spectra can be judged by quality indicators and also the ADI-to-AEI similarity to determine the optimum light spectrum. However we found some IBO measured results showing erroneous indication of wafer expansion from the difference between the ADI and the AEI maps, even after their measurement spectra were optimized. To reduce this inconsistency, an improved image calculation algorithm is proposed in this paper. Different gray levels composed of inner- and outer-box contours are extracted to calculate their ADI overlay errors. The symmetry of intensity distribution at the thresholds dictated by a range of gray levels is used to determine the particular gray level that can minimize the ADI-to-AEI overlay inconsistency. After this improvement, the ADI is more similar to AEI with less expansion difference. The same wafer was also checked by the diffraction-based overlay (DBO) tool to verify that there is no physical wafer expansion. When there is actual wafer expansion induced by large internal stress, both the IBO and the DBO measurements indicate similar expansion results. The scanning white-light interference microscope was used to check the variation of wafer warpage during the ADI and AEI stages. It predicts a similar trend with the overlay difference map, confirming the internal stress.

Estimation of Value-at-Risk for Energy Commodities via CAViaR Model

NASA Astrophysics Data System (ADS)

Xiliang, Zhao; Xi, Zhu

This paper uses the Conditional Autoregressive Value at Risk model (CAViaR) proposed by Engle and Manganelli (2004) to evaluate the value-at-risk for daily spot prices of Brent crude oil and West Texas Intermediate crude oil covering the period May 21th, 1987 to Novermber 18th, 2008. Then the accuracy of the estimates of CAViaR model, Normal-GARCH, and GED-GARCH was compared. The results show that all the methods do good job for the low confidence level (95%), and GED-GARCH is the best for spot WTI price, Normal-GARCH and Adaptive-CAViaR are the best for spot Brent price. However, for the high confidence level (99%), Normal-GARCH do a good job for spot WTI, GED-GARCH and four kind of CAViaR specifications do well for spot Brent price. Normal-GARCH does badly for spot Brent price. The result seems suggest that CAViaR do well as well as GED-GARCH since CAViaR directly model the quantile autoregression, but it does not outperform GED-GARCH although it does outperform Normal-GARCH.

Cosmological Parameters from the QUAD CMB Polarization Experiment

NASA Astrophysics Data System (ADS)

Castro, P. G.; Ade, P.; Bock, J.; Bowden, M.; Brown, M. L.; Cahill, G.; Church, S.; Culverhouse, T.; Friedman, R. B.; Ganga, K.; Gear, W. K.; Gupta, S.; Hinderks, J.; Kovac, J.; Lange, A. E.; Leitch, E.; Melhuish, S. J.; Memari, Y.; Murphy, J. A.; Orlando, A.; Pryke, C.; Schwarz, R.; O'Sullivan, C.; Piccirillo, L.; Rajguru, N.; Rusholme, B.; Taylor, A. N.; Thompson, K. L.; Turner, A. H.; Wu, E. Y. S.; Zemcov, M.; QUa D Collaboration

2009-08-01

In this paper, we present a parameter estimation analysis of the polarization and temperature power spectra from the second and third season of observations with the QUaD experiment. QUaD has for the first time detected multiple acoustic peaks in the E-mode polarization spectrum with high significance. Although QUaD-only parameter constraints are not competitive with previous results for the standard six-parameter ΛCDM cosmology, they do allow meaningful polarization-only parameter analyses for the first time. In a standard six-parameter ΛCDM analysis, we find the QUaD TT power spectrum to be in good agreement with previous results. However, the QUaD polarization data show some tension with ΛCDM. The origin of this 1σ-2σ tension remains unclear, and may point to new physics, residual systematics, or simple random chance. We also combine QUaD with the five-year WMAP data set and the SDSS luminous red galaxies 4th data release power spectrum, and extend our analysis to constrain individual isocurvature mode fractions, constraining cold dark matter density, αcdmi < 0.11 (95% confidence limit (CL)), neutrino density, αndi < 0.26 (95% CL), and neutrino velocity, αnvi < 0.23 (95% CL), modes. Our analysis sets a benchmark for future polarization experiments.

Human olfactory bulb neural stem cells expressing hNGF restore cognitive deficit in Alzheimer's disease rat model.

PubMed

Marei, Hany E S; Farag, Amany; Althani, Asma; Afifi, Nahla; Abd-Elmaksoud, Ahmed; Lashen, Samah; Rezk, Shaymaa; Pallini, Roberto; Casalbore, Patrizia; Cenciarelli, Carlo

2015-01-01

In this study, we aim to demonstrate the fate of allogenic adult human olfactory bulb neural stem/progenitor cells (OBNSC/NPCs) transplanted into the rat hippocampus treated with ibotenic acid (IBO), a neurotoxicant specific to hippocampal cholinergic neurons that are lost in Alzheimer's disease. We assessed their possible ability to survive, integrate, proliferate, and differentiate into different neuronal and glial elements: we also evaluate their possible therapeutic potential, and the mechanism(s) relevant to neuroprotection following their engraftment into the CNS milieu. OBNSC/NPCs were isolated from adult human olfactory bulb patients, genetically engineered to express GFP and human nerve growth factor (hNGF) by lentivirus-mediated infection, and stereotaxically transplanted into the hippocampus of IBO-treated animals and controls. Stereological analysis of engrafted OBNSCs eight weeks post transplantation revealed a 1.89 fold increase with respect to the initial cell population, indicating a marked ability for survival and proliferation. In addition, 54.71 ± 11.38%, 30.18 ± 6.00%, and 15.09 ± 5.38% of engrafted OBNSCs were identified by morphological criteria suggestive of mature neurons, oligodendrocytes and astrocytes respectively. Taken together, this work demonstrated that human OBNSCs expressing NGF ameliorate the cognitive deficiencies associated with IBO-induced lesions in AD model rats, and the improvement can probably be attributed primarily to neuronal and glial cell replacement as well as the trophic influence exerted by the secreted NGF. © 2014 Wiley Periodicals, Inc.

Integrating Primary Sources, Artifacts, and Museum Visits into the Primary Years Program Inquiry Curriculum in an International Baccalaureate Elementary Setting

ERIC Educational Resources Information Center

Coppersmith, Sarah A.; Song, Kim H.

2017-01-01

Questions remain about inquiry instruction, while research confirms that using primary sources can aid students' inquiry learning processes. This study questioned: "How do second-grade teachers at an International Baccalaureate Organization/IBO language immersion setting incorporate inquiry methods in instructional practices?"; "How…

Advanced Placement and International Baccalaureate: Do They Deserve Gold Star Status?

ERIC Educational Resources Information Center

Byrd, Sheila

2007-01-01

For many people committed to strong academic standards, the "advanced" high school courses offered through the College Board's Advanced Placement program and, increasingly, the Diploma Programme of the International Baccalaureate Organisation (IBO) represent the curricular gold standard for secondary education. Admissions directors and…

Sex Differences in the Acquisition of Conservation by Selected Nigerian Children.

ERIC Educational Resources Information Center

Onyehalu, Anthony Sunday

1984-01-01

Hypothesized that there would be no significant sex differences in the performance of conservation tasks on substance or volume, among 247 Ibo-speaking Nigerian children. Attributed confirmation of the hypothesis to social change and greater sexual equality in this developing society. (GC)

Effect of Variables Independent of Performance on Promotion Rates to Major, Lieutenant Colonel, and Colonel in the Marine Corps

DTIC Science & Technology

1992-09-01

1 54. 1 71. 50s css/3:Cfautsbulation (count) tables For ALS-N &MARSTAT-M &SOURCE-USNA & DEGREE-UNDRG3RAD SELECTED DUrYSTA QUA FMF NON HOM REC 104 3...MARS1’AT-M & SOURCE- USNA __________________& DEGREE-UNDRGRAD ____ ________ SELECTED DUTrYSTA QUA FMF NON HQM REC 104 1 2.9 29. 62. 6.7 0 N so 33...M & SOURCE-OCS ___________________& DEGREE-ADVANCED ____ ________ SELECrED DUTrYSTA QUA FMF NON HOM REC N 72 7 2241 1 1 Y 198 471 104 16 3 X~SELECMD

A study on chaos in crude oil markets before and after 2008 international financial crisis

NASA Astrophysics Data System (ADS)

Lahmiri, Salim

2017-01-01

The purpose of this study is to investigate existence of chaos in crude oil markets (Brent and WTI) before and after recent 2008 international financial crisis. Largest Lyapunov exponent is estimated for prices, returns, and volatilities. The empirical results show strong evidence that chaos does not exist in prices and returns in both crude oil markets before and after international crisis. However, we find strong evidence of chaotic dynamics in both Brent and WTI volatilities after international financial crisis.

Lesions of the amygdala central nucleus abolish lipoprivic-enhanced responding during oil-predicting conditioned stimuli.

PubMed

Benoit, S C; Morell, J R; Davidson, T L

1999-12-01

T. L. Davidson, A. M. Altizer, S. C. Benoit, E. K. Walls, and T. L. Powley (1997) reported that rats show facilitated responding to conditioned stimuli (CSs) that predict oil, after administration of the lipoprivic agent, Na-2-mercaptoacetate (MA). This facilitation was blocked by vagal deafferentation. The present article extends that investigation to another structure, the amygdala central nucleus (CN). The CN receives inputs from dorsal vagal nuclei, and neurotoxic lesions of this nucleus are reported to abolish feeding in response to lipoprivic challenges. In Experiment 1, rats with ibotenic acid (IBO) lesions of the CN failed to show enhanced appetitive responding during oil-predicting CSs after administration of MA. Experiment 2 used a conditioned taste-aversion procedure to establish that rats with IBO lesions of the CN were able to discriminate the tastes of sucrose and peanut oil and had intact CS-US representations. It is concluded that the amygdala CN is a necessary structure for the detection of lipoprivic challenges.

Roles for SOF in a Staggering Nigeria

DTIC Science & Technology

2009-04-01

languages and approximately 350 ethno-linguistic groups, Nigeria can indubitably be dubbed a cultural patchwork. Three dominant groups, the Ibo, Yoruba ...critical factors ................................................................................................................ 4 A cultural patchwork...continue to be the U.S. military force of choice for operations and exercises within Africa.”10 Culturally attuned, experienced in working with

Constructing Knowledge in a New World.

ERIC Educational Resources Information Center

Solis, Ed

2002-01-01

Considers how the events of September 11th made fear drive students away from acceptance and interest in what was before a cultural learning experience. Discusses students' reactions to Chinua Achebe's novel "Things Fall Apart," which depicts colonization from the point of the Ibo people. Concludes that curriculum may need to address…

Nigeria: Hydrocarbon Curse Fueling Instability in Niger Delta

DTIC Science & Technology

2010-03-15

Christians and Muslims. 12 The largest ethnic groups are the Hausa-Fulani in theNorth, the Ibo in the Southeast, and the Yoruba in the Southwest. 13 Nigeria...0). AllAfrica.com. "Nigeria: The Fading Culture of Party System in Nigeria." http://allafrica.com/stories/200803190577.htm I (accessed February 9

The Academic Impact of Enrollment in International Baccalaureate Diploma Programs: A Case Study of Chicago Public Schools

ERIC Educational Resources Information Center

Saavedra, Anna Rosefsky

2014-01-01

Background: In schools accredited as "IB World Schools" by the International Baccalaureate Organization (IBO), teachers use IB curriculum and pedagogy to teach a range of courses that are intended to prepare IB-enrolled students for college. Over the past 18 years, the number of U.S. schools that implement IB programs has increased…

The adaptive significance of hatching synchrony of waterfowl eggs

USGS Publications Warehouse

Flint, Paul L.; Lindberg, Mark S.; MacCluskie, Margaret C.; Sedinger, James S.

1994-01-01

We estimated the amount of incubation time that first laid Black Brent eggs received before completion of the clutch. First laid eggs received up to 48 hours of incubation before the last egg was laid in Brent clutches. Waterfowl clutches usually hatch within a period of 24 hours, suggesting that some mechanism reduces developmental asynchrony during incubation. The combination of incubation during laying and hatch synchronization mechanisms should be adaptive because these traits reduce nest exposure, maintain egg viability, and result in an earlier hatch date, all of which increase fitness in waterfowl.

Effect of postoperative peroxide bleaching on the marginal seal of composite restorations bonded with self-etch adhesives.

PubMed

Roubickova, A; Dudek, M; Comba, L; Housova, D; Bradna, P

2013-01-01

The aim of this study was to determine the effect of peroxide bleaching on the marginal seal of composite restorations bonded with several adhesive systems. Combined cylindrical Class V cavities located half in enamel and half in dentin were prepared on the buccal and lingual surfaces of human molars. The cavities were bonded with the self-etch adhesives Clearfil SE-Bond (CLF), Adper Prompt (ADP), and iBond (IBO) and an etch-and-rinse adhesive Gluma Comfort Bond (GLU) and restored with a microhybrid composite Charisma. Experimental groups were treated 25 times for eight hours per day with a peroxide bleaching gel Opalescence PF 20, while the control groups were stored in distilled water for two months and then subjected to a microleakage test using a dye penetration method. Scanning electron microscopy was used to investigate the etching and penetration abilities of the adhesives and morphology of debonded restoration-enamel interfaces after the microleakage tests. Statistical analyses were performed using nonparametric Kruskal-Wallis, Mann-Whitney, and Wilcoxon tests at p=0.05. The microleakage of all GLU groups was low and not significantly affected by peroxide bleaching. Low microleakage was recorded for CLF control groups, but after bleaching, a small but significant increase in microleakage at the enamel margin indicated its sensitivity to peroxide bleaching. For ADP and IBO control groups, the microleakage at the enamel margins was significantly higher than for GLU and CLF and exceeded that at the dentin margins. Bleaching did not induce any significant changes in the microleakage. Electron microscopy analysis indicated that in our experimental setup, decreased adhesion and mechanical resistance of the ADP- and IBO-enamel interfaces could be more important than the chemical degradation effects induced by the peroxide bleaching gel.

Evidence for Time-of-Day Dependent Effect of Neurotoxic Dorsomedial Hypothalamic Lesions on Food Anticipatory Circadian Rhythms in Rats

PubMed Central

Landry, Glenn J.; Kent, Brianne A.; Patton, Danica F.; Jaholkowski, Mark; Marchant, Elliott G.; Mistlberger, Ralph E.

2011-01-01

The dorsomedial hypothalamus (DMH) is a site of circadian clock gene and immediate early gene expression inducible by daytime restricted feeding schedules that entrain food anticipatory circadian rhythms in rats and mice. The role of the DMH in the expression of anticipatory rhythms has been evaluated using different lesion methods. Partial lesions created with the neurotoxin ibotenic acid (IBO) have been reported to attenuate food anticipatory rhythms, while complete lesions made with radiofrequency current leave anticipatory rhythms largely intact. We tested a hypothesis that the DMH and fibers of passage spared by IBO lesions play a time-of-day dependent role in the expression of food anticipatory rhythms. Rats received intra-DMH microinjections of IBO and activity and body temperature (T b) rhythms were recorded by telemetry during ad-lib food access, total food deprivation and scheduled feeding, with food provided for 4-h/day for 20 days in the middle of the light period and then for 20 days late in the dark period. During ad-lib food access, rats with DMH lesions exhibited a lower amplitude and mean level of light-dark entrained activity and T b rhythms. During the daytime feeding schedule, all rats exhibited food anticipatory activity and T b rhythms that persisted during 2 days without food in constant dark. In some rats with partial or total DMH ablation, the magnitude of the anticipatory rhythm was weak relative to most intact rats. When mealtime was shifted to the late night, the magnitude of the food anticipatory activity rhythms in these cases was restored to levels characteristic of intact rats. These results confirm that rats can anticipate scheduled daytime or nighttime meals without the DMH. Improved anticipation at night suggests a modulatory role for the DMH in the expression of food anticipatory activity rhythms during the daily light period, when nocturnal rodents normally sleep. PMID:21912674

Image-based overlay measurement using subsurface ultrasonic resonance force microscopy

NASA Astrophysics Data System (ADS)

Tamer, M. S.; van der Lans, M. J.; Sadeghian, H.

2018-03-01

Image Based Overlay (IBO) measurement is one of the most common techniques used in Integrated Circuit (IC) manufacturing to extract the overlay error values. The overlay error is measured using dedicated overlay targets which are optimized to increase the accuracy and the resolution, but these features are much larger than the IC feature size. IBO measurements are realized on the dedicated targets instead of product features, because the current overlay metrology solutions, mainly based on optics, cannot provide sufficient resolution on product features. However, considering the fact that the overlay error tolerance is approaching 2 nm, the overlay error measurement on product features becomes a need for the industry. For sub-nanometer resolution metrology, Scanning Probe Microscopy (SPM) is widely used, though at the cost of very low throughput. The semiconductor industry is interested in non-destructive imaging of buried structures under one or more layers for the application of overlay and wafer alignment, specifically through optically opaque media. Recently an SPM technique has been developed for imaging subsurface features which can be potentially considered as a solution for overlay metrology. In this paper we present the use of Subsurface Ultrasonic Resonance Force Microscopy (SSURFM) used for IBO measurement. We used SSURFM for imaging the most commonly used overlay targets on a silicon substrate and photoresist. As a proof of concept we have imaged surface and subsurface structures simultaneously. The surface and subsurface features of the overlay targets are fabricated with programmed overlay errors of +/-40 nm, +/-20 nm, and 0 nm. The top layer thickness changes between 30 nm and 80 nm. Using SSURFM the surface and subsurface features were successfully imaged and the overlay errors were extracted, via a rudimentary image processing algorithm. The measurement results are in agreement with the nominal values of the programmed overlay errors.

The Cultural Impact upon Human Struggle for Social Existence in Chinua Achebe's "Things Fall Apart"

ERIC Educational Resources Information Center

El-Dessouky, Mohamed Fawzy

2010-01-01

This paper aims at introducing an insight into the nature of cultural conflict as depicted in Chinua Achebe's "Things Fall Apart." This study shows how the African black culture represented by Ibo tribe comes into disagreement with the white one imposed by the British imperialism. The greatness of Achebe lies in the vivid description of…

Diffraction-based overlay metrology for double patterning technologies

NASA Astrophysics Data System (ADS)

Dasari, Prasad; Korlahalli, Rahul; Li, Jie; Smith, Nigel; Kritsun, Oleg; Volkman, Cathy

2009-03-01

The extension of optical lithography to 32nm and beyond is made possible by Double Patterning Techniques (DPT) at critical levels of the process flow. The ease of DPT implementation is hindered by increased significance of critical dimension uniformity and overlay errors. Diffraction-based overlay (DBO) has shown to be an effective metrology solution for accurate determination of the overlay errors associated with double patterning [1, 2] processes. In this paper we will report its use in litho-freeze-litho-etch (LFLE) and spacer double patterning technology (SDPT), which are pitch splitting solutions that reduce the significance of overlay errors. Since the control of overlay between various mask/level combinations is critical for fabrication, precise and accurate assessment of errors by advanced metrology techniques such as spectroscopic diffraction based overlay (DBO) and traditional image-based overlay (IBO) using advanced target designs will be reported. A comparison between DBO, IBO and CD-SEM measurements will be reported. . A discussion of TMU requirements for 32nm technology and TMU performance data of LFLE and SDPT targets by different overlay approaches will be presented.

A study and simulation of the impact of high-order aberrations to overlay error distribution

NASA Astrophysics Data System (ADS)

Sun, G.; Wang, F.; Zhou, C.

2011-03-01

With reduction of design rules, a number of corresponding new technologies, such as i-HOPC, HOWA and DBO have been proposed and applied to eliminate overlay error. When these technologies are in use, any high-order error distribution needs to be clearly distinguished in order to remove the underlying causes. Lens aberrations are normally thought to mainly impact the Matching Machine Overlay (MMO). However, when using Image-Based overlay (IBO) measurement tools, aberrations become the dominant influence on single machine overlay (SMO) and even on stage repeatability performance. In this paper, several measurements of the error distributions of the lens of SMEE SSB600/10 prototype exposure tool are presented. Models that characterize the primary influence from lens magnification, high order distortion, coma aberration and telecentricity are shown. The contribution to stage repeatability (as measured with IBO tools) from the above errors was predicted with simulator and compared to experiments. Finally, the drift of every lens distortion that impact to SMO over several days was monitored and matched with the result of measurements.

The role of benchmark crudes in crude oil pricing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wildblood, P.

1993-12-31

Most of the world`s oil, whether sold on a spot basis or as part of a term contract, will be priced on a relationship with one or other of a small number of marker crude oils. Generally, the markers used are West Texas Intermediate (WTI) and Alaskan North Slope (ANS) for crude oil coming into North and South America; Dubai or Oman for crudes being delivered into the Far Eastern markets; and Brent for any crude being delivered into Europe. For a variety of reasons, over the laster two years, Brent blend has become more predominant in the pricing processmore » for crude oils throughout the world. This has resulted in the fact that, directly or indirectly, Brent is now used to price approximately 65% of the world`s crude oil. So why is it that a crude oil with a comparatively small production base of around 700,000 barrels per day has now come to dominate the pricing of the lion`s share of the world`s crude oil? The answer to this question is discussed.« less

Structure–function studies of STAR family Quaking proteins bound to their in vivo RNA target sites

PubMed Central

Teplova, Marianna; Hafner, Markus; Teplov, Dmitri; Essig, Katharina; Tuschl, Thomas; Patel, Dinshaw J.

2013-01-01

Mammalian Quaking (QKI) and its Caenorhabditis elegans homolog, GLD-1 (defective in germ line development), are evolutionarily conserved RNA-binding proteins, which post-transcriptionally regulate target genes essential for developmental processes and myelination. We present X-ray structures of the STAR (signal transduction and activation of RNA) domain, composed of Qua1, K homology (KH), and Qua2 motifs of QKI and GLD-1 bound to high-affinity in vivo RNA targets containing YUAAY RNA recognition elements (RREs). The KH and Qua2 motifs of the STAR domain synergize to specifically interact with bases and sugar-phosphate backbones of the bound RRE. Qua1-mediated homodimerization generates a scaffold that enables concurrent recognition of two RREs, thereby plausibly targeting tandem RREs present in many QKI-targeted transcripts. Structure-guided mutations reduced QKI RNA-binding affinity in vitro and in vivo, and expression of QKI mutants in human embryonic kidney cells (HEK293) significantly decreased the abundance of QKI target mRNAs. Overall, our studies define principles underlying RNA target selection by STAR homodimers and provide insights into the post-transcriptional regulatory function of mammalian QKI proteins. PMID:23630077

Effect of shoe heel height and total-contact insert on muscle loading and foot stability while walking.

PubMed

Hong, Wei-Hsien; Lee, Yung-Hui; Lin, Yen-Hui; Tang, Simon F T; Chen, Hsieh-Ching

2013-02-01

Women wearing high-heeled shoes often complain of foot instability and low-back pain. Previous studies have demonstrated that using total-contact inserts (TCIs) in running shoes reduces impact on leg muscles and alters rearfoot motion. This study investigated how shoe heel height and use of TCIs in high-heeled shoes affect the wearer's rearfoot complex, muscle loading, and subjective comfort. Fifteen inexperienced high heel wearers walked under 6 test conditions formed by the cross-matching of shoe insert (with and without TCI) and heel height (1.0, 5.1, and 7.6 cm) at a speed of 1.3 m/s. The measures of interest were rearfoot kinematics; muscle activities by electromyography (EMG) of the tibialis anterior (TA), medial gastrocnemius (MG), quadriceps (QUA), hamstrings (HAM), and erector spinae (ES); and subjective comfort rating by visual analogue scale for each test condition. The statistical results showed that elevated heel height significantly increased plantar flexion (P < .001) and inversion (P < .01) at heel strike, prolonged TA-MG co-contraction (P < .001) and QUA activation period (P < .001), and increased root mean square (RMS) EMG in all measured muscles (TA, MG, QUA, ES: P < .001; HAM: P < .01). The use of TCIs reduced the rearfoot inversion angle (P < .01) and RMS EMG in both QUA and ES muscles (P < .01) and increased comfort rating (P < .001). These findings suggest that wearing high-heeled shoes adversely affects muscle control and reduces loads in QUA and ES muscles. The use of a TCI may improve comfort rating and foot stability.

The organization pattern of root border-like cells of Arabidopsis is dependent on cell wall homogalacturonan.

PubMed

Durand, Caroline; Vicré-Gibouin, Maïté; Follet-Gueye, Marie Laure; Duponchel, Ludovic; Moreau, Myriam; Lerouge, Patrice; Driouich, Azeddine

2009-07-01

Border-like cells are released by Arabidopsis (Arabidopsis thaliana) root tips as organized layers of several cells that remain attached to each other rather than completely detached from each other, as is usually observed in border cells of many species. Unlike border cells, cell attachment between border-like cells is maintained after their release into the external environment. To investigate the role of cell wall polysaccharides in the attachment and organization of border-like cells, we have examined their release in several well-characterized mutants defective in the biosynthesis of xyloglucan, cellulose, or pectin. Our data show that among all mutants examined, only quasimodo mutants (qua1-1 and qua2-1), which have been characterized as producing less homogalacturonan, had an altered border-like cell phenotype as compared with the wild type. Border-like cells in both lines were released as isolated cells separated from each other, with the phenotype being much more pronounced in qua1-1 than in qua2-1. Further analysis of border-like cells in the qua1-1 mutant using immunocytochemistry and a set of anti-cell wall polysaccharide antibodies showed that the loss of the wild-type phenotype was accompanied by (1) a reduction in homogalacturonan-JIM5 epitope in the cell wall of border-like cells, confirmed by Fourier transform infrared microspectrometry, and (2) the secretion of an abundant mucilage that is enriched in xylogalacturonan and arabinogalactan-protein epitopes, in which the cells are trapped in the vicinity of the root tip.

The Organization Pattern of Root Border-Like Cells of Arabidopsis Is Dependent on Cell Wall Homogalacturonan12[C][W

PubMed Central

Durand, Caroline; Vicré-Gibouin, Maïté; Follet-Gueye, Marie Laure; Duponchel, Ludovic; Moreau, Myriam; Lerouge, Patrice; Driouich, Azeddine

2009-01-01

Border-like cells are released by Arabidopsis (Arabidopsis thaliana) root tips as organized layers of several cells that remain attached to each other rather than completely detached from each other, as is usually observed in border cells of many species. Unlike border cells, cell attachment between border-like cells is maintained after their release into the external environment. To investigate the role of cell wall polysaccharides in the attachment and organization of border-like cells, we have examined their release in several well-characterized mutants defective in the biosynthesis of xyloglucan, cellulose, or pectin. Our data show that among all mutants examined, only quasimodo mutants (qua1-1 and qua2-1), which have been characterized as producing less homogalacturonan, had an altered border-like cell phenotype as compared with the wild type. Border-like cells in both lines were released as isolated cells separated from each other, with the phenotype being much more pronounced in qua1-1 than in qua2-1. Further analysis of border-like cells in the qua1-1 mutant using immunocytochemistry and a set of anti-cell wall polysaccharide antibodies showed that the loss of the wild-type phenotype was accompanied by (1) a reduction in homogalacturonan-JIM5 epitope in the cell wall of border-like cells, confirmed by Fourier transform infrared microspectrometry, and (2) the secretion of an abundant mucilage that is enriched in xylogalacturonan and arabinogalactan-protein epitopes, in which the cells are trapped in the vicinity of the root tip. PMID:19448034

Multifractal analysis on international crude oil markets based on the multifractal detrended fluctuation analysis

NASA Astrophysics Data System (ADS)

Gu, Rongbao; Chen, Hongtao; Wang, Yudong

2010-07-01

The multifractal nature of WTI and Brent crude oil markets is studied employing the multifractal detrended fluctuation analysis. We find that two crude oil markets become more and more efficient for long-term and two Gulf Wars cannot change time scale behavior of crude oil return series. Considering long-term influence caused by Gulf Wars, we find such “turning windows” in generalized Hurst exponents obtained from three periods divided by two Gulf Wars so that WTI and Brent crude oil returns possess different properties above and below the windows respectively. Comparing with the results obtained from three periods we conclude that, before the First Gulf War, international crude oil markets possessed the highest multifractality degree, small-scope fluctuations presented the strongest persistence and large-scope fluctuations presented the strongest anti-persistence. We find that, for two Gulf Wars, the first one made a greater impact on international oil markets; for two markets, Brent was more influenced by Gulf Wars. In addition, we also verified that the multifractal structures of two markets’ indices are not only mainly attributed to the broad fat-tail distributions and persistence, but also affected by some other factors.

[Record linkage of a large clinical practice patient cohort with the Cancer Registry Schleswig-Holstein].

PubMed

Obi, N; Waldmann, A; Babaev, V; Katalinic, A

2011-07-01

A precondition for the evaluation of outcomes in cohort studies and screening programmes is the availability of follow-up data. In Germany, established cancer registries provide such data for incident primary cancer diseases and mortality. To utilise these cancer registry data a person's identifying code has to be correctly linked to study or programme records, a procedure which, up to date, has been only rarely used in Germany. Exemplarily, the feasibility and validity of record linkage of a cohort of 173 050 patients from the Quality-assured Mamma Diagnostic programme (QuaMaDi) to the cancer registry Schleswig-Holstein was assessed by the accuracy of the classified outcome. Name, date of birth and address of the QuaMaDi cohort members were coded in the confidential administration center of the registry. These codes were passed by the codes of 129 455 female cancer registry records. Datasets were synchronised for each match, so that QuaMaDi participants could be identified in the registry file. In a next step epidemiological registry records were linked to the QuaMaDi study records. The accuracy of classifying outcome was assessed by agreement measures, i. e., Cohen's kappa. In cases of disagreement, a questionnaire has been sent to QuaMaDi patients' gynaecologists to validate the final diagnosis. Synchronisation of both cohorts resulted in 18 689 one to one matches with any kind of malignant tumour, therein 8 449 breast cancers (ICD-10 C50, D05). Absolute agreement between files according to diagnosed or suspected breast cancer was 97.6% with a kappa value of 0.79. When suspicious BIRADS 4 cases from QuaMaDi were excluded, agreement and kappa rose to 99.5% and 0.948, respectively. After correction of the final diagnosis according to the physician's responses, agreement measures slightly improved in both groups of ascertained diagnosis including and excluding the suspected cases. Within QuaMaDi the diagnosed breast cancer cases were predominantly

76 FR 20436 - Ninth Meeting: RTCA Special Committee 223: Airport Surface Wireless Communications

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-12

..., Administrative Remarks by Special Committee Leadership [ssbox] Designated Federal Officer (DFO): Mr. Brent... Results Update--ITT [ssbox] AeroMACS load estimations and performance evaluations--Max Ehammer (University...

Time-frequency featured co-movement between the stock and prices of crude oil and gold

NASA Astrophysics Data System (ADS)

Huang, Shupei; An, Haizhong; Gao, Xiangyun; Huang, Xuan

2016-02-01

The nonlinear relationships among variables caused by the hidden frequency information complicate the time series analysis. To shed more light on this nonlinear issue, we examine their relationships in joint time-frequency domain with multivariate framework, and the analyses in the time domain and frequency domain serve as comparisons. The daily Brent oil prices, London gold fixing price and Shanghai Composite index from January 1991 to September 2014 are adopted as example. First, they have long-term cointegration relationship in time domain from holistic perspective. Second, the Granger causality tests in different frequency bands are heterogeneous. Finally, the comparison between results from wavelet coherence and multiple wavelet coherence in the joint time-frequency domain indicates that in the high (1-14 days) and medium frequency (14-128 days) bands, the combination of Brent and gold prices has stronger correlation with the stock. In the low frequency band (256-512 days), year 2003 is the structure broken point before which Brent and oil are ideal choice for hedging the risk of the stock market. Thus, this paper offers more details between the Chinese stock market and the commodities markets of crude oil and gold, which suggests that the decisions for different time and frequencies should consider the corresponding benchmark information.

Ectopic Cushing syndrome

MedlinePlus

... 7/2017 Updated by: Brent Wisse, MD, Associate Professor of Medicine, Division of Metabolism, Endocrinology & Nutrition, University of Washington School of Medicine, Seattle, WA. Also reviewed by David ...

Cushing syndrome due to adrenal tumor

MedlinePlus

... 7/2017 Updated by: Brent Wisse, MD, Associate Professor of Medicine, Division of Metabolism, Endocrinology & Nutrition, University of Washington School of Medicine, Seattle, WA. Also reviewed by David ...

Effects of knee and ankle muscle fatigue on postural control in the unipedal stance.

PubMed

Bizid, Riadh; Margnes, Eric; François, Yrieix; Jully, Jean Louis; Gonzalez, Gerard; Dupui, Philippe; Paillard, Thierry

2009-06-01

The aim of this study was to compare the effects of acute muscle fatigue of the ankle and knee musculature on postural control by immediate measures after performing fatiguing tasks (POST condition). One group of subjects (n = 8) performed a fatiguing task by voluntary contractions of the triceps surae (group TRI) and the other (n = 9) performed a fatiguing task by voluntary contractions of the quadriceps femoris (group QUA). Each muscle group was exercised until the loss of maximal voluntary contraction torque reached 50% (isokinetic dynamometer). Posture was assessed by measuring the centre of foot pressure (COP) with a force platform during a test of unipedal quiet standing posture with eyes closed. Initially (in PRE condition), the mean COP velocity was not significantly different between group TRI and group QUA. In POST condition, the mean COP velocity increased more in group QUA than in group TRI. The postural control was more impaired by knee muscle fatigue than by ankle muscle fatigue.

STS-81 Flight Day 8

NASA Technical Reports Server (NTRS)

1997-01-01

On this eighth day of the STS-81 mission, the flight crew, Cmdr. Michael A. Baker, Pilot Brent W. Jett, Mission Specialists, John M. Grunsfeld, Marsha S. Ivins, Peter J.K. Wisoff, and John Blaha, bid farewell to Jerry Linenger and cosmonauts of Mir. Prior to hatch closure, the astronauts and cosmonauts conduct a formal farewell ceremony in the Mir Core Module. They then field questions from Russian and U.S. reporters in a joint news conference. Commander Mike Baker, Pilot Brent Jett and Mission Specialists Jeff Wisoff, John Grunsfeld, Marsha Ivins and John Blaha say goodbye to Mir 22 Commander Valery Korzun, Flight Engineer Alexander Kaleri and the newest Mir crewmember, astronaut Jerry Linenger. The hatches on the two spacecraft are closed.

Nigeria: Current Issues

DTIC Science & Technology

2007-04-12

Hausa-Fulani, the southwestern Yoruba , and the southeastern Ibo have traditionally been the most politically active and dominant. Almost half of the...Adamawa State in the January elections, was chosen by the PDP as the running mate of Obasanjo, a Yoruba from southwestern Nigeria. The APP and AD...nominated Chief Olu Falae, a Yoruba , as their joint candidate for president. A former Nigerian security chief and a northerner, Chief Umaru Shinakfi, was

DynaGuard: Armoring Canary-Based Protections against Brute-Force Attacks

DTIC Science & Technology

2015-12-11

public domain. Non-exclusive copying or redistribution is...sje ng 462 .lib qua ntu m 464 .h2 64r ef 471 .om net pp 473 .as tar 483 .xa lan cbm k Apa che Ng inx Pos tgre SQ L SQ Lite My SQ L Sl ow do w n (n...k 456 .hm me r 458 .sje ng 462 .lib qua ntu m 464 .h2 64r ef 471 .om net pp 473 .as tar 483 .xa lan cbm k Apa che Ng inx Pos tgre SQ L SQ Lite My

Brent Olson - Director, Office of Internal Audit | NREL

Science.gov Websites

improve the effectiveness and efficiency of governance, risk management, and control processes. Using this the Treadway Commission's 2013 Internal Control Framework, Standards for Internal Control in the additional certifications from IIA including Certified Internal Auditor (CIA); Certification in Control Self

An isotopic assessment of protein from diet and endogenous stores: Effects on egg production and incubation behaviour of geese

USGS Publications Warehouse

Schmutz, J.A.; Hobson, K.A.; Morse, J.A.

2006-01-01

Little empirical information exists to assess to what degree geese use a capital versus income breeding strategy for investing nutrients into eggs. We used stable isotope methods to directly estimate the sources of protein deposited into egg yolks of Brent Branta bernicla and Emperor Geese Anser canagicus on the Yukon-Kuskokwim Delta, Alaska, USA. Approximately 59 and 45% of protein in egg yolks of Brent and Emperor Geese, respectively, was derived from exogenous sources (i.e. food plants on the local breeding area). Within clutches of Brent Goose eggs, first-laid eggs exhibited slightly higher contributions from endogenous reserves than last-laid eggs. This pattern was less clear for Emperor Geese, which may have been a consequence of possibly analyzing eggs that were laid by intraspecific nest parasites rather than by hosts. For both these species, individuals exhibited large variability in the percent contribution of exogenous versus endogenous stores to eggs, and future studies should identify ecological factors related to this variation. Those Emperor Geese in poor body condition incubated their nests less constantly, and based on δ13C values, they fed on terrestrial foods while off their nests. Although not a pure capital breeder, Emperor Geese used nutrients garnered on spring staging areas to fuel virtually all their own maintenance during incubation and to contribute half or more of the nutrients in eggs. These results highlight the ecological importance of these spring staging habitats to geese.

From "Stranger" to "Arrived": The Citizens' Library in England.

ERIC Educational Resources Information Center

Meyers, Arthur S.

1998-01-01

Discusses studies of public library multicultural services in England. Describes multicultural programs in Birmingham and Brent that involve the citizens in planning and implementing these services. Access to electronic technology will affect the provision of these services. (MMU)

Prolotherapy: An Effective Treatment for Low Back Pain?

MedlinePlus

... pain? Is prolotherapy an effective treatment for chronic low back pain? Answers from Brent A. Bauer, M.D. Prolotherapy is ... reduced pain. Studies of prolotherapy in people with low back pain have had mixed results. A combination of prolotherapy ...

Can Glucosamine Supplements Protect My Knee Cartilage from Osteoarthritis?

MedlinePlus

... Can glucosamine supplements protect my knee cartilage from osteoarthritis? Answers from Brent A. Bauer, M.D. Study results on this question have ... build cartilage. The most common type of arthritis, osteoarthritis wears away the slick cartilage that covers the ...

Building a Clean Energy Future for Power Production | Working with Us |

Science.gov Websites

Rice Brent Rice EXECUTIVE MANAGER, STRATEGIC PARTNERSHIPS Email me Photo of a man and a woman stand Partnership Successes Photo of a man and a woman stand next to a gas storage tank and bioreactor. Partnering

Educating in Global Times: Race, Class, Gender (and Other Processes of Normalization). Graduate Student Research Conference Proceedings (Edmonton, Alberta, Canada, March 14-15, 1997.)

ERIC Educational Resources Information Center

Alberta Univ., Edmonton.

The 33 papers presented at this conference are, as follows: "Child Participation in an Everyday Adult Practice" (Andrew Brent Andressen); "Education for Sustainable Development in Southern Philippines" (Caridad Bernardino); "Distance Education and Instructional Technologies: Cultural Transmission or Cultural Erosion"…

High-efficiency Gaussian key reconciliation in continuous variable quantum key distribution

NASA Astrophysics Data System (ADS)

Bai, ZengLiang; Wang, XuYang; Yang, ShenShen; Li, YongMin

2016-01-01

Efficient reconciliation is a crucial step in continuous variable quantum key distribution. The progressive-edge-growth (PEG) algorithm is an efficient method to construct relatively short block length low-density parity-check (LDPC) codes. The qua-sicyclic construction method can extend short block length codes and further eliminate the shortest cycle. In this paper, by combining the PEG algorithm and qua-si-cyclic construction method, we design long block length irregular LDPC codes with high error-correcting capacity. Based on these LDPC codes, we achieve high-efficiency Gaussian key reconciliation with slice recon-ciliation based on multilevel coding/multistage decoding with an efficiency of 93.7%.

SeaQuaKE: Sea-optimized Quantum Key Exchange

DTIC Science & Technology

2014-06-01

is led by Applied Communications Sciences under the ONR Free Space Optical Quantum Key Distribution Special Notice (13-SN-0004 under ONRBAA13-001...In addition, we discuss our initial progress towards the free - space quantum channel model and planning for the experimental validation effort. 15...SUBJECT TERMS Quantum communications, free - space optical communications 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT Same as

Management Qua Communication in Rocket Research and Development

ERIC Educational Resources Information Center

Tompkins, Phillip K.

1977-01-01

Reviews a diagnostic study conducted by a communication consultant within the George C Marshall Space Flight Center during the research and development of the Saturn V or "Moon Rocket". Participant observation and in-depth interview methodology yields information on organizational communication and systematic problems within a complex network. (MH)

SeaQuaKE: Sea-optimized Quantum Key Exchange

DTIC Science & Technology

2015-01-01

of photon pairs in both polarization [3] and time-bin [4] degrees of freedom simultaneously. Entanglement analysis components in both the...greater throughput per entangled photon pair compared to alternative sources that encode in only a Photon -pair source Time-bin entanglement ...Polarization Entanglement & Pair Generation Hyperentangled Photon Pair Source •Wavelength availability • Power • Pulse rate Time-bin Mux • Waveguide vs

SeaQuaKE: Sea-optimized Quantum Key Exchange

DTIC Science & Technology

2014-11-01

ONRBAA13-001). In this technical report, we describe modeling results of an entangled photon - pair source based on spontaneous four-wave mixing for...Distribution Special Notice (13-SN- 0004 under ONRBAA13-001). In this technical report, we describe modeling results of an entangled photon - pair ...areas over the last quarter include (i) development of a wavelength-dependent, entangled photon - pair source model and (ii) end-to-end system modeling

76 FR 31677 - Notice of Final Federal Agency Actions on Proposed Highway in California

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-01

... Transportation (Caltrans) assumed, environmental responsibilities for this project pursuant to 23 U.S.C. 327... applies. FOR FURTHER INFORMATION CONTACT: Melanie Brent, Caltrans District 4 Office of Environmental... Mitigated Negative Declaration/Environmental Assessment (IS/EA) for the project, approved on March 18, 2011...

Protecting the Privacy of Individuals in Terrorist Tracking Applications

DTIC Science & Technology

2005-04-01

THE PRIVACY OF INDIVIDUALS IN TERRORIST TRACKING APPLICATIONS 6. AUTHOR(S) Teresa Lunt, Paul Aoki, Dirk Balfanz , Glenn Durfee, Philippe Golle...in Data Mining and Knowledge Discovery. 3) Brent Waters, Dirk Balfanz , Glenn Durfee, and Diana Smetters. Building an encrypted and searchable audit

From Fiction to Field Notes: Observing Ibo Culture in "Things Fall Apart."

ERIC Educational Resources Information Center

Schur, Joan Brodsky

1997-01-01

Demonstrates how introducing students to African literature can appeal to their imaginations and encourage them to develop their insights into African culture. Outlines the procedures in a middle school class where the students are transformed into anthropologists as they read Chinua Achebe's, "Things Fall Apart." (MJP)

Design and Testing of Bi-functional, P-loop Targeted MDM2 Inhibitors

DTIC Science & Technology

2008-03-01

Nucleotide Binding Activity of the Mdm2 RING Domain Christina Priest, Masha Poyurovsky, Brent Stockwell and Carol Prives Department of Biological Sciences...Deconstructing nucleotide binding activity of the Mdm2 RING domain Christina Priest, Carol Prives* and Masha V. Poyurovsky Department of Biological Sciences

Collegiate Aviation Research and Education Solutions to Critical Safety Issues. UNO Aviation Monograph Series. UNOAI Report.

ERIC Educational Resources Information Center

Bowen, Brent, Ed.

This document contains four papers concerning collegiate aviation research and education solutions to critical safety issues. "Panel Proposal Titled Collegiate Aviation Research and Education Solutions to Critical Safety Issues for the Tim Forte Collegiate Aviation Safety Symposium" (Brent Bowen) presents proposals for panels on the…

Inferring Action Structure and Causal Relationships in Continuous Sequences of Human Action

DTIC Science & Technology

2014-01-01

language processing literature (e.g., Brent, 1999; Venkataraman , 2001), and which were also used by Goldwater et al. (2009). Precision (P) is the...trees in oriented linear graphs. Simon Stevin: Wis-en Natuurkundig Tijdschrift, 28 , 203. Venkataraman , A. (2001). A statistical model for word discovery

Provision for the Development of the Linguistic Proficiency of Young Immigrants in England and Wales and France: A Comparative Study.

ERIC Educational Resources Information Center

Loewenberg, Monica; Wass, Bob

1997-01-01

Compares educational policies and practices related to developing the linguistic competence of young immigrants in France and England, with particular reference to Toulouse and the London borough of Brent. Discusses segregationist versus integrationist approaches, effectiveness of second-language instruction, and provision of mother-tongue…

77 FR 64334 - Environmental Impacts Statements; Notice of Availability

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-19

..., Jack Rabbit to Big Sky Meadow Village 161 kV Transmission Line Upgrade, Bozeman Ranger District..., Lakewood Southeast Project, Proposes to Manage Vegetation and Habitat, Lakewood-Laona Ranger District... Interchange Project, Improvements, Solano County, CA, Review Period Ends: 11/19/2012, Contact: Melanie Brent...

Quantum-SAR Extension of the Spectral-SAR Algorithm. Application to Polyphenolic Anticancer Bioactivity

PubMed Central

Putz, Mihai V.; Putz, Ana-Maria; Lazea, Marius; Ienciu, Luciana; Chiriac, Adrian

2009-01-01

Aiming to assess the role of individual molecular structures in the molecular mechanism of ligand-receptor interaction correlation analysis, the recent Spectral-SAR approach is employed to introduce the Quantum-SAR (QuaSAR) “wave” and “conversion factor” in terms of difference between inter-endpoint inter-molecular activities for a given set of compounds; this may account for inter-conversion (metabolization) of molecular (concentration) effects while indicating the structural (quantum) based influential/detrimental role on bio-/eco- effect in a causal manner rather than by simple inspection of measured values; the introduced QuaSAR method is then illustrated for a study of the activity of a series of flavonoids on breast cancer resistance protein. PMID:19399244

Malnutrition in the Field. Nigerian Civil War 1968-9

PubMed Central

Hughes, S. P. F.

1969-01-01

A short-term, large-scale medical and feeding programme has been provided for a population of 150,000 in the bush area near Udi in eastern Nigeria (Biafra). By January 1969 8,000 patients were receiving medical treatment each week for varying degrees of protein malnutrition (including kwashiorkor), vitamin deficiency, and dehydration; while 100,000 received weekly rations of a protein-supplemented diet. Close cooperation between the medical team—which consisted of one doctor, four nurses, and two relief workers—and the local Ibo people contributed to the success of the relief programme. PMID:5781491

The effect of individually-induced processes on image-based overlay and diffraction-based overlay

NASA Astrophysics Data System (ADS)

Oh, SeungHwa; Lee, Jeongjin; Lee, Seungyoon; Hwang, Chan; Choi, Gilheyun; Kang, Ho-Kyu; Jung, EunSeung

2014-04-01

In this paper, set of wafers with separated processes was prepared and overlay measurement result was compared in two methods; IBO and DBO. Based on the experimental result, theoretical approach of relationship between overlay mark deformation and overlay variation is presented. Moreover, overlay reading simulation was used in verification and prediction of overlay variation due to deformation of overlay mark caused by induced processes. Through this study, understanding of individual process effects on overlay measurement error is given. Additionally, guideline of selecting proper overlay measurement scheme for specific layer is presented.

17 CFR 20.2 - Covered contracts.

Code of Federal Regulations, 2014 CFR

2014-04-01

.... 2 Heating Oil, New York Harbor. NYMEX Palladium. NYMEX Platinum. NYMEX Sugar No. 11. NYMEX Uranium... Ethanol. CBOT Oats. CBOT Rough Rice. CBOT Soybean Meal. CBOT Soybean Oil. CBOT Soybeans. CBOT Wheat.... NYMEX Brent Financial. NYMEX Central Appalachian Coal. NYMEX Coffee. NYMEX Cotton. NYMEX Crude Oil...

17 CFR 20.2 - Covered contracts.

Code of Federal Regulations, 2013 CFR

2013-04-01

.... 2 Heating Oil, New York Harbor. NYMEX Palladium. NYMEX Platinum. NYMEX Sugar No. 11. NYMEX Uranium... Ethanol. CBOT Oats. CBOT Rough Rice. CBOT Soybean Meal. CBOT Soybean Oil. CBOT Soybeans. CBOT Wheat.... NYMEX Brent Financial. NYMEX Central Appalachian Coal. NYMEX Coffee. NYMEX Cotton. NYMEX Crude Oil...

17 CFR 20.2 - Covered contracts.

Code of Federal Regulations, 2012 CFR

2012-04-01

.... 2 Heating Oil, New York Harbor. NYMEX Palladium. NYMEX Platinum. NYMEX Sugar No. 11. NYMEX Uranium... Ethanol. CBOT Oats. CBOT Rough Rice. CBOT Soybean Meal. CBOT Soybean Oil. CBOT Soybeans. CBOT Wheat.... NYMEX Brent Financial. NYMEX Central Appalachian Coal. NYMEX Coffee. NYMEX Cotton. NYMEX Crude Oil...

Multilevel algorithms for nonlinear optimization

NASA Technical Reports Server (NTRS)

Alexandrov, Natalia; Dennis, J. E., Jr.

1994-01-01

Multidisciplinary design optimization (MDO) gives rise to nonlinear optimization problems characterized by a large number of constraints that naturally occur in blocks. We propose a class of multilevel optimization methods motivated by the structure and number of constraints and by the expense of the derivative computations for MDO. The algorithms are an extension to the nonlinear programming problem of the successful class of local Brown-Brent algorithms for nonlinear equations. Our extensions allow the user to partition constraints into arbitrary blocks to fit the application, and they separately process each block and the objective function, restricted to certain subspaces. The methods use trust regions as a globalization strategy, and they have been shown to be globally convergent under reasonable assumptions. The multilevel algorithms can be applied to all classes of MDO formulations. Multilevel algorithms for solving nonlinear systems of equations are a special case of the multilevel optimization methods. In this case, they can be viewed as a trust-region globalization of the Brown-Brent class.

Neither Very Bi nor Particularly Sexual: The Essence of the Bisexual in Young Adult Literature

ERIC Educational Resources Information Center

Kneen, Bonnie

2015-01-01

This article examines four prominent young adult novels about bisexual protagonists: Julie Anne Peters's "It's Our Prom (So Deal With It)" (2012), Brent Hartinger's Double Feature: "Attack of the Soul-Sucking Brain Zombies/Bride of the Soul-Sucking Brain Zombies" (2007), Lili Wilkinson's "Pink" (2009), and Sara Ryan's…

Jett, Tanner and Garneau during re-entry preparations for STS-97

NASA Image and Video Library

2000-12-11

STS097-310-032 (11 December 2000) --- Astronauts (left to right) Marc Garneau, Joseph R. Tanner, both mission specialists, and Brent W. Jett, mission commander, are photographed on the flight deck of the Space Shuttle Endeavour as they prepare for re-entry. Garneau represents the Canadian Space Agency (CSA).

77 FR 76318 - Self-Regulatory Organizations; ICE Clear Europe Limited; Notice of Filing and Immediate...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-27

... Methodology is an enhancement to the SPAN for the ICE Margining algorithm employed to calculate Original... Margining algorithm employed to calculate Original Margin and was designed to optimize and improve margin... framework algorithm. The enhancement will be additionally applied to: GOA: Gas Oil 1-Month CSO; BRZ: Brent...

Exploring Antecedents of Performance Differences on Visual and Verbal Test Items: Learning Styles versus Aptitude

ERIC Educational Resources Information Center

Bacon, Donald R.; Hartley, Steven W.

2015-01-01

Many educators and researchers have suggested that some students learn more effectively with visual stimuli (e.g., pictures, graphs), whereas others learn more effectively with verbal information (e.g., text) (Felder & Brent, 2005). In two studies, the present research seeks to improve popular self-reported (indirect) learning style measures…

The Aeronautics Education, Research, and Industry Alliance (AERIAL) 2002 Report. UNO Aviation Monograph Series. UNOAI Report.

ERIC Educational Resources Information Center

Bowen, Brent D.; Box, Richard C.; Fink, Mary M.; Gogos, George; Lehrer, Henry R.; Narayanan, Ram M.; Nickerson, Jocelyn S.; O'Neil, Patrick D.; Tarry, Scott E.; Vlasek, Karisa D.

This document contains four papers on aeronautics education, research, and partnerships that partly supported through the Aeronautics Education, Research, and Industry Alliance (AERIAL). The paper "2002 AERIAL Monograph" (Brent D. Bowen, Jocelyn S. Nickerson, Mary M. Fink, et al.) presents an overview of research and development in the…

A NOVEL S-ADENOSYL-L-METHIONINE: ARSENIC (III) METHYLTRANSFERASE FROM RAT LIVER CYTOSOL

EPA Science Inventory

A Novel S-Adenosyl-L-methionine: Arsenic(III) Methyltransferase from Rat Liver Cytosol
Shan Lin, Qing Shi, F. Brent Nix, Miroslav Styblo, Melinda A. Beck, Karen M. Herbin-Davis, Larry L. Hall, Josef B. Simeonsson, and David J. Thomas
S-adenosyl-L-methionine (AdoMet): ar...

What Leaders Need to Know and Do: A Leadership Competencies Scorecard

ERIC Educational Resources Information Center

Ruben, Brent D.

2006-01-01

Brent Ruben introduces readers to a framework that surveys, summarizes, and synthesizes a broad cross section of the contemporary writings on leadership. The book organizes that literature into five broad competency areas, each of which is composed of a number of themes, and provides a Leadership Competencies Scorecard Inventory that allows…

Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (82nd, New Orleans, Louisiana, August 3-8, 1999). Media and Disabilities.

ERIC Educational Resources Information Center

Association for Education in Journalism and Mass Communication.

The Media and Disabilities section of the Proceedings contains the following 5 papers: "Wrestling with Stereotypes: Images of the Mentally Ill in the WWF" (Marie Hardin and Brent Hardin); "Investigating Media Influence on Attitudes Toward People with Disabilities and Euthanasia" (Kimberly A. Lauffer and Sarah Bembry); "Print Advertising Images of…

Fulbright Hays Summer Seminars Abroad Program, 1988. Curriculum Projects.

ERIC Educational Resources Information Center

National Committee on United States-China Relations, New York, NY.

This document consists of a collection of 18 curriculum projects created by U.S. teachers after visiting China during 1988. The projects cover a variety of topics concerning China: "Chinese Living Environments" (R. Stumpe Brent); "China as a Model of a Mixed Economy in a Developing Nation" (G. Caressi); "Images of…

77 FR 21106 - Notice of Proposed Reinstatement of Terminated Oil and Gas Lease NDM 95190, North Dakota

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-09

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [LLMT922200-12-L13100000-FI0000-P; NDM95190... of Land Management, Interior. ACTION: Notice. SUMMARY: Per 30 U.S.C. 188(d), ABACO Energy LLC, Brent..., Panther Energy Company LLC, David Peterson, Rainbow Energy Marketing Corporation, Red Willow Great Plains...

STS-81 crewmembers participate in bailout training in Bldg 29 WETF

NASA Image and Video Library

1996-09-26

S96-15393 (26 Sept. 1996) --- In the Johnson Space Center's weightless environment training facility, astronaut Brent W. Jett Jr., STS-81 mission specialist, deploys his "Mae West" device to stay afloat during water bailout survival training. Five STS-81 crewmates, out of frame, joined him for the bailout training exercises.

76 FR 7590 - Distribution of 2000, 2001, 2002, and 2003 Cable Royalty Funds

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-10

.... ADDRESSES: An original, five copies, and an electronic copy in Portable Document Format (PDF) on a CD of the... INFORMATION CONTACT: LaKeshia Brent, CRB Program Specialist, by telephone at (202) 707-7658, or e-mail at crb... of the major categories of copyrightable content (movies, sports programming, music, etc.) requesting...

75 FR 1716 - Revisions to the California State Implementation Plan, San Joaquin Valley Unified Air Pollution...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-13

... NO X 12. Definition of ``Major Source'' 13. Sunset Provision for Section 185 Fees III. EPA Action IV... from Ted Steichen, dated September 18, 2009. 3. Association of Irritated Residents, letter from Brent... or emissions during the baseline period, or the amount of VOC or NO X emissions allowed under the...

Specifications for embankment and subgrade compaction.

DOT National Transportation Integrated Search

2005-01-01

Six approaches were developed for specifying embankment and subgrade compaction and/or verifying compaction quality on Virginia Department of Transportation (VDOT) construction projects. These approaches, along with VDOT's current practices, were qua...

Mechanism of mRNA-STAR domain interaction: Molecular dynamics simulations of Mammalian Quaking STAR protein.

PubMed

Sharma, Monika; Anirudh, C R

2017-10-03

STAR proteins are evolutionary conserved mRNA-binding proteins that post-transcriptionally regulate gene expression at all stages of RNA metabolism. These proteins possess conserved STAR domain that recognizes identical RNA regulatory elements as YUAAY. Recently reported crystal structures show that STAR domain is composed of N-terminal QUA1, K-homology domain (KH) and C-terminal QUA2, and mRNA binding is mediated by KH-QUA2 domain. Here, we present simulation studies done to investigate binding of mRNA to STAR protein, mammalian Quaking protein (QKI). We carried out conventional MD simulations of STAR domain in presence and absence of mRNA, and studied the impact of mRNA on the stability, dynamics and underlying allosteric mechanism of STAR domain. Our unbiased simulations results show that presence of mRNA stabilizes the overall STAR domain by reducing the structural deviations, correlating the 'within-domain' motions, and maintaining the native contacts information. Absence of mRNA not only influenced the essential modes of motion of STAR domain, but also affected the connectivity of networks within STAR domain. We further explored the dissociation of mRNA from STAR domain using umbrella sampling simulations, and the results suggest that mRNA binding to STAR domain occurs in multi-step: first conformational selection of mRNA backbone conformations, followed by induced fit mechanism as nucleobases interact with STAR domain.

Diffraction based overlay re-assessed

NASA Astrophysics Data System (ADS)

Leray, Philippe; Laidler, David; D'havé, Koen; Cheng, Shaunee

2011-03-01

In recent years, numerous authors have reported the advantages of Diffraction Based Overlay (DBO) over Image Based Overlay (IBO), mainly by comparison of metrology figures of merit such as TIS and TMU. Some have even gone as far as to say that DBO is the only viable overlay metrology technique for advanced technology nodes; 22nm and beyond. Typically the only reported drawback of DBO is the size of the required targets. This severely limits its effective use, when all critical layers of a product, including double patterned layers need to be measured, and in-die overlay measurements are required. In this paper we ask whether target size is the only limitation to the adoption of DBO for overlay characterization and control, or are there other metrics, which need to be considered. For example, overlay accuracy with respect to scanner baseline or on-product process overlay control? In this work, we critically re-assess the strengths and weaknesses of DBO for the applications of scanner baseline and on-product process layer overlay control. A comprehensive comparison is made to IBO. For on product process layer control we compare the performance on critical process layers; Gate, Contact and Metal. In particularly we focus on the response of the scanner to the corrections determined by each metrology technique for each process layer, as a measure of the accuracy. Our results show that to characterize an overlay metrology technique that is suitable for use in advanced technology nodes requires much more than just evaluating the conventional metrology metrics of TIS and TMU.

Rockets and spacecraft: Sine qua non of space science

NASA Technical Reports Server (NTRS)

1980-01-01

The evolution of the national launch vehicle stable is presented along with lists of launch vehicles used in NASA programs. A partial list of spacecraft used throughout the world is also given. Scientific spacecraft costs are presented along with an historial overview of project development and funding in NASA.

Sine Qua Non: Indispensable Resources for Ed Tech Professionals

ERIC Educational Resources Information Center

Conley, Kate

2004-01-01

This is the third and final article in the series on indispensable resources compiled from suggestions provided by ISTE members and affiliates; staff; and board, committee, and advocate network members. These essential resources deal directly with the challenges of designing successful instructional activities incorporating technology to engage…

Model for Evaluating the Cost Consequences of Deferring New System Acquisition Through Upgrades

DTIC Science & Technology

1999-07-01

Analysis & Evaluation The Pentagon Washington, DC 20301 Attn: Mr. Eric Coulter, Director Projection Forces Division, Room 2E314 Lt Col Kathleen Conley...1034 Office of the Air National Guard ANG/AQM 5109 Leesburg Pike Skyline VI, Suite 302A Falls Church, VA 22041-3201 Attn: Col Brent Marler 1 Lt Col

Technology and Teacher Education Annual 1992. Proceedings of the Annual Conference on Technology and Teacher Education (3rd, Houston, Texas, March 12-15, 1992).

ERIC Educational Resources Information Center

Carey, Doris, Ed.; And Others

The 147 papers in this collection represent the cutting edge in the field of information technology for teacher education. The keynote address, presented by Thomas F. Ryan of Illinois State University, is entitled "Using Technology: A College of Education's Experience." Following that is an invited paper presented by Brent Robinson of the…

Shakespeare, The Tragedies: A collection of Critical Essays. Twentieth Century Views Series.

ERIC Educational Resources Information Center

Harbage, Alfred, Ed.

One of a series of works aimed at presenting contemporary critical opinion on major authors, this collection includes essays by Alfred Harbage, H. B. Charlton, Willard Farnham, H. T. Price, Donald A. Stauffer, Brents Stirling, Maynard Mack, Helen Gardner, C. S. Lewis, Alvin Kernan, Bernard Spivack, L. C. Knights, Francis Fergusson, G. Wilson…

A Review Of The United States Government’s Status Quo North Korean Foreign Policy Approach And Reasons For Change

DTIC Science & Technology

2016-02-16

unity over South China Sea, Yahoo News, Jan 2016. http://news.yahoo.com/kerry-press-china-over-north-korea- urge-asean-014102596.html 38 Brent Choi...34 Yahoo News. Jan 24, 2016. http://news.yahoo.com/kerry-press-china-over- north-korea-urge-asean-014102596.html (accessed Jan 24, 2016). Bunn, M. Elaine

Chasing Rainbows: A Comment on School Choice and the National Football League

ERIC Educational Resources Information Center

Beal, Brent D.; Olson Beal, Heather K.

2013-01-01

In this article, Brent Beal, and Heather Olson Beal respond to comments made about their article: "Rethinking the Market Metaphor: School Choice, the Common Good, and the National Football League," appearing in this issue of the Journal of School Choice. Comments were made by Vitteritti, Houck, Coulson, Bast, and Merrifield. In their…

Lines of Deterritorialization: The Becoming-Minor of Carter's Drawing

ERIC Educational Resources Information Center

Schulte, Christopher M.

2015-01-01

Invoking Gilles Deleuze and Félix Guattari's configuration of minor literature, the author of this case study theorizes the drawing practice of a young boy (Carter) as a process of becoming-minor. Critical to this theorization is the creation and activation of a semblance between Brent and Marjorie Wilson's (1977) treatment of the…

76 FR 77329 - Schedules of Controlled Substances: Placement of Carisoprodol Into Schedule IV

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-12

... lifetime for a non- medical reason. Id. at 89. While observing that the yearly estimates ``may remain... FDA approval as the sine qua non of the ``currently accepted medical use'' and ``accepted safety for...

Discovery of Emerging Per-and Polyfluoroalkyl Substances

EPA Science Inventory

Legacy perfluorinated compounds exhibit significant environmental persistence and bioaccumulation potential, which has spawned an ongoing effort to introduce replacement compounds with reduced toxicological risk profiles. Many of these emerging chemical species lack validated qua...

Maternal Personality, Parenting Cognitions and Parenting Practices

PubMed Central

Bornstein, Marc H.; Hahn, Chun-Shin; Haynes, O. Maurice

2011-01-01

A community sample of 262 European American mothers of firstborn 20-month-olds completed a personality inventory and measures of parenting cognitions (knowledge, self-perceptions, and reports about behavior) and was observed in interaction with their children from which measures of parenting practices (language, sensitivity, affection, and play) were independently coded. Factor analyses of the personality inventory replicated extraction of the Five-Factor model of personality (Openness, Neuroticism, Extraversion, Agreeableness, and Conscientiousness). Controlling for sociodemographic characteristics, the five personality factors qua variables and in patterns qua clusters related differently to diverse parenting cognitions and practices, supporting the multidimensional, modular, and specific nature of parenting. Maternal personality in the normal range, a theoretically important but empirically neglected factor in everyday parenting, has meaning in studies of parenting, child development, and family process. PMID:21443335

RME 1327 - Crew Medical Restraint System (CMRS)

NASA Image and Video Library

1997-02-18

STS081-318-031 (12-22 Jan. 1997) --- Astronauts Brent W. Jett, Jr. (left), STS-81 pilot, and John E. Blaha in the Spacehab Double Module (DM) evaluate the Crew Medical Restraint System (CMRS) carrier, onboard the Space Shuttle Atlantis. The device is an emergency aid forerunner for hardware on the International Space Station (ISS).

Telling It like It Is: Teaching Mechanisms in Organic Chemistry

ERIC Educational Resources Information Center

Ault, Addison

2010-01-01

In this article I support and extend the ideas presented by J. Brent Friesen in his article "Saying What You Mean; Teaching Mechanisms in Organic Chemistry" ("JCE" November, 2008). I emphasize "telling the truth" about proton transfers. The truth is that in aqueous acid most reactions are subject to "specific" acid catalysis: the only kinetically…

Justice for All, All for Justice.

ERIC Educational Resources Information Center

Wolowiec, Jack, Ed.

1993-01-01

This document presents three articles on law-related education (LRE) written either by or for students. Brent Halling, a senior at Castle High School in Newburgh, Indiana, opens the collection with an article on how due process protects rights. Halling explains the concept of due process and illustrates its reach through the case of Kenneth…

The Effects of Mothers' Past Infant-Holding Preferences on Their Adult Children's Face Processing Lateralisation

ERIC Educational Resources Information Center

Vervloed, Mathijs P. J.; Hendriks, Angelique W.; van den Eijnde, Esther

2011-01-01

Face processing development is negatively affected when infants have not been exposed to faces for some time because of congenital cataract blocking all vision (Le Grand, Mondloch, Maurer, & Brent, 2001). It is not clear, however, whether more subtle differences in face exposure may also have an influence. The present study looked at the effect of…

The Conference Proceedings of the 1998 Air Transport Research Group (ATRG) of the WCTR Society. Volume 4

NASA Technical Reports Server (NTRS)

Bowen, Brent D. (Editor); Oum, Tae Hoon (Editor)

1998-01-01

The Air Transport Research Group of the WCTR Society was formally launched as a special interest group at the 7h Triennial WCTR in Sydney, Australia in 1995. Since then, our membership base has expanded rapidly, and now includes over 400 active transportation researchers, policy-makers, industry executives, major corporations and research institutes from 28 countries. It became a tradition that the ATRG would hold an international conference at least once a year. In 1998, the ATRG organized a consecutive stream of 14 aviation sessions at the 8th Triennial WCTR Conference (July 12-17: Antwerp). Again, on 19-21 July, 1998, the ATRG Symposium was organized and executed every successfully by Dr. Aisling Reynolds-Feighan of the University College of Dublin. The Aviation Institute at the University of Nebraska at Omaha has published the Proceedings of the 1998 ATRG Dublin Symposium (being co-edited by Dr. Aisling Reynolds-Feighan and Professor Brent Bowen), and the Proceedings of the 1998 WCTR- ATRG Conference (being co-edited by Professors Tae H. Oum and Brent Bowen).

The Symposium Proceedings of the 1998 Air Transport Research Group (ATRG). Volume 2

NASA Technical Reports Server (NTRS)

Reynolds-Feighan, Aisling (Editor); Bowen, Brent D. (Editor)

1998-01-01

The Air Transport Research Group of the World Conference on Transportation Research (WCTR) Society was formally launched as a special interest group at the 7th Triennial WCTR in Sydney, Australia in 1995. Since then, our membership base has expanded rapidly, and now includes over 400 active transportation researchers, policy-makers, industry executives, major corporations and research institutes from 28 countries. It became a tradition that the ATRG would hold an international conference at least once a year. In 1998, the ATRG organized a consecutive stream of 14 aviation sessions at the 8th Triennial WCTR Conference (July 12-17: Antwerp). Again, on 19-21 July, 1998, the ATRG Symposium was organized and executed very successfully by Dr. Aisling Reynolds-Feighan of the University College of Dublin. The Aviation Institute at the University of Nebraska at Omaha has published the Proceedings of the 1998 ATRG Dublin Symposium (being co-edited by Dr. Aisling Reynolds-Feighan and Professor Brent Bowen), and the Proceedings of the 1998 WCTR-ATRG Conference (being co-edited by Professors Tae H. Oum and Brent Bowen).

A Framework for Evaluating Energy and Emissions of Connected and Automated Vehicles through Traffic Microsimulations

DOT National Transportation Integrated Search

2018-01-07

Connected and automated vehicles (CAV) are poised to transform surface transportation systems in the United States. Near-term CAV technologies like cooperative adaptive cruise control (CACC) have the potential to deliver energy efficiency and air qua...

Water quality mitigation banking : final report, December 2009.

DOT National Transportation Integrated Search

2009-12-01

Current practice in New Jersey for mitigating stormwater impacts caused by transportation infrastructure : projects is established by NJDEP Stormwater Regulations (N.J.A.C. 7:8). These rules outline specific : processes to offset impacts to water qua...

ASSESSING ALTERNATIVE FUTURES FOR AGRICULTURE IN IOWA, U.S.A.

EPA Science Inventory

The contributions of current industrial agricultural practices to environmental degradation and the social problems facing agricultural regions are well known. However, landscape-scale alternatives to current conditions have not been fully explored nor their potential impacts qua...

Capturing Uncertainty in Fatigue Life Data

DTIC Science & Technology

2014-09-18

CAPTURING UNCERTAINTY IN FATIGUE LIFE DATA THESIS Brent D. Russell AFIT-ENS-T-14-S-15 DEPARTMENT OF THE AIR FORCE AIR...UNLIMITED. i The views expressed in this thesis are those of the author and do not...reflect the official policy or position of the United States Air Force, Department of Defense, or the United States Government

76 FR 70212 - Qualification of Drivers; Exemption Applications; Vision

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-10

.... Hershberger Patrick J. Hogan, Jr. Todd A. McBrian Amilton T. Monteiro Harold W. Mumford John W. Myre David G. Oakley Charles D. Oestreich John S. Olsen Thomas J. Prusik Brent L. Seaux Glen W. Sterling The exemptions.... Bequeaith Lloyd K. Brown Larry Chinn Kecia D. Clark-Welch Tommy R. Crouse Ben W. Davis Charles A. DeKnikker...

Hiring the Next Generation of Faculty. New Directions for Community Colleges, Number 152

ERIC Educational Resources Information Center

Cejda, Brent D., Ed.; Murray, John P., Ed.

2011-01-01

This volume contains the following papers: (1) Preparing to Hire the Best in the Perfect Storm (John P. Murray); (2) New Faculty Issues: Fitting In and Figuring It Out (Pamela L. Eddy); (3) An Approach to a Faculty Professional Development Seminar (Mary Bendickson and Karen Griffin); (4) Faculty Issues in Rural Community Colleges (Brent D. Cejda);…

Intergalactic Encounters: Desire and the Political Immediacy of Children's Drawing

ERIC Educational Resources Information Center

Schulte, Christopher M.

2015-01-01

The author of this article creates a semblance between Deleuze and Guattari's conception of a politics of desire and the four realities, as outlined by Brent and Marjorie Wilson. By making this theoretical move, the author advances the idea that children's drawing unfolds from one moment to the next through the assemblages of desire that are most…

Challenges in Europe an Higher Education

ERIC Educational Resources Information Center

Orphanides, Andreas G.

2012-01-01

Quality assurance has been one of the most important components of the Bologna Process and the EHEA. Quality and innovation are "sine qua non" in achieving competitiveness, especially when the focus is on its challenges in a global context.

EVALUATION OF MULTIPLE AQUATIC BIOMONITORS FOR SOURCE WATER PROTECTION

EPA Science Inventory

A variety of probes for use in continuous monitoring of water quality exist. They range from single parameter chemical/physical probes to comprehensive screening systems based on whole organism responses. Originally developed for monitoring specific characteristics of water qua...

WATER QUALITY EARLY WARNING SYSTEMS FOR SOURCE WATER AND DISTRIBUTION SYSTEM MONITORING

EPA Science Inventory

A variety of probes for use in continuous monitoring of water quality exist. They range from single parameter chemical/physical probes to comprehensive screening systems based on whole organism responses. Originally developed for monitoring specific characteristics of water qua...

Using macroinvertebrate response to inform sediment criteria development in mountain streams

EPA Science Inventory

The phrase biologically-based sediment criterion indicates that biological data is used to develop regional sediment criteria that will protect and maintain self-sustaining populations of native sediment-sensitive biota. To develop biologically-based sediment criteria we must qua...

Hybrid overlay metrology with CDSEM in a BEOL patterning scheme

NASA Astrophysics Data System (ADS)

Leray, Philippe; Jehoul, Christiane; Inoue, Osamu; Okagawa, Yutaka

2015-03-01

Overlay metrology accuracy is a major concern for our industry. Advanced logic process require more tighter overlay control for multipatterning schemes. TIS (Tool Induced Shift) and WIS (Wafer Induced Shift) are the main issues for IBO (Image Based Overlay) and DBO (Diffraction Based Overlay). Methods of compensation have been introduced, some are even very efficient to reduce these measured offsets. Another related question is about the overlay target designs. These targets are never fully representative of the design rules, strong efforts have been achieved, but the device cannot be completely duplicated. Ideally, we would like to measure in the device itself to verify the real overlay value. Top down CDSEM can measure critical dimensions of any structure, it is not dependent of specific target design. It can also measure the overlay errors but only in specific cases like LELE (Litho Etch Litho Etch) after final patterning. In this paper, we will revisit the capability of the CDSEM at final patterning by measuring overlay in dedicated targets as well as inside a logic and an SRAM design. In the dedicated overlay targets, we study the measurement differences between design rules gratings and relaxed pitch gratings. These relaxed pitch which are usually used in IBO or DBO targets. Beyond this "simple" LELE case, we will explore the capability of the CDSEM to measure overlay even if not at final patterning, at litho level. We will assess the hybridization of DBO and CDSEM for reference to optical tools after final patterning. We will show that these reference data can be used to validate the DBO overlay results (correctables and residual fingerprints).

Faster diffraction-based overlay measurements with smaller targets using 3D gratings

NASA Astrophysics Data System (ADS)

Li, Jie; Kritsun, Oleg; Liu, Yongdong; Dasari, Prasad; Volkman, Catherine; Hu, Jiangtao

2012-03-01

Diffraction-based overlay (DBO) technologies have been developed to address the overlay metrology challenges for 22nm technology node and beyond. Most DBO technologies require specially designed targets that consist of multiple measurement pads, which consume too much space and increase measurement time. The traditional empirical approach (eDBO) using normal incidence spectroscopic reflectometry (NISR) relies on linear response of the reflectance with respect to overlay displacement within a small range. It offers convenience of quick recipe setup since there is no need to establish a model. However it requires three or four pads per direction (x or y) which adds burden to throughput and target size. Recent advances in modeling capability and computation power enabled mDBO, which allows overlay measurement with reduced number of pads, thus reducing measurement time and DBO target space. In this paper we evaluate the performance of single pad mDBO measurements using two 3D targets that have different grating shapes: squares in boxes and L-shapes in boxes. Good overlay sensitivities are observed for both targets. The correlation to programmed shifts and image-based overlay (IBO) is excellent. Despite the difference in shapes, the mDBO results are comparable for square and L-shape targets. The impact of process variations on overlay measurements is studied using a focus and exposure matrix (FEM) wafer. Although the FEM wafer has larger process variations, the correlation of mDBO results with IBO measurements is as good as the normal process wafer. We demonstrate the feasibility of single pad DBO measurements with faster throughput and smaller target size, which is particularly important in high volume manufacturing environment.

RADIOANALYTICAL AND MIXED WASTE ANALYTICAL SUPPORT FOR STATES, REGIONS, AND OTHER FEDERAL AGENCIES

EPA Science Inventory

Provide technical advice and support to Regions and other Federal Agencies on types of analyses, proper sampling, preservation, shipping procedures, and detection limits for samples for radionuclides and stable metals. Provide in-house data review and validation to ensure the qua...

Air Quality Criteria for Lead (Final Report, 1986)

EPA Science Inventory

The Air Quality Criteria documents evaluate and assesse scientific information on the health and welfare effects associated with exposure to various concentrations of lead in ambient air. The literature through 1985 has been reviewed thoroughly for information relevant to air qua...

Aquaculture genomics, genetics and breeding in the United States: Current status, challenges, and priorities for future research

USDA-ARS?s Scientific Manuscript database

Advancing the production efficiency and profitability of aquaculture is dependent upon the ability to utilize a diverse array of genetic resources. The ultimate goals of aquaculture genomics, genetics and breeding research are to enhance aquaculture production efficiency, sustainability, product qua...

Temperature and nutrient effects on periphyton associated bacterial communities in continuous flow-through estuarine mesocosms

EPA Science Inventory

Nutrient pollution is a leading cause of water quality impairments and degraded aquatic ecosystem condition. Reliable and reproducible indicators of ecosystem condition are needed to help manage nutrient pollution. The diatom component of periphyton has been used as a water qua...

Investigation and Evaluation of Ground Tire Rubber in Hot Mix Asphalt

DOT National Transportation Integrated Search

1989-08-01

The purpose of this study, which is published in five volumes, was to identify and verify using all available state-of-the-art sources, how ground tire rubber can be utilized in asphalt concrete mixtures for pavement construction meeting standard qua...

Ultrahydrophobic Fluorinated Polyhedral Oligomeric Silsesquioxanes (F-POSS) (Preprint)

DTIC Science & Technology

2007-01-25

From - To) 25-01-2007 Journal Article 4. TITLE AND SUBTITLE 5a. CONTRACT NUMBER Ultrahydrophobic Fluorinated Polyhedral Oligomeric Silsesquioxanes...Ultrahydrophobic Fluorinated Polyhedral Oligomeric Silsesquioxanes (F-POSS) Joseph M. Mabry,* Ashwani Vij,* Scott T. Iacono, and Brent D. Viers Recently...there exists a demand to construct ultrahydrophobic materials inspired by nature that are easy to prepare on a large scale. Polyhedral oligomeric

Basic Color Terms in Estonian Sign Language

ERIC Educational Resources Information Center

Hollman, Liivi; Sutrop, Urmas

2011-01-01

The article is written in the tradition of Brent Berlin and Paul Kay's theory of basic color terms. According to this theory there is a universal inventory of eleven basic color categories from which the basic color terms of any given language are always drawn. The number of basic color terms varies from 2 to 11 and in a language having a fully…

Acoustic Wave Monitoring of Biofilm Development in Porous Media

EPA Science Inventory

Biofilm development in porous media can result in significant changes to the hydrogeological properties of subsurface systems with implications for fluid flow and contaminant transport. As such, a number of numerical models and simulations have been developed in an attempt to qua...

The Rise and Demise of the International Council for Science Policy Studies (ICSPS) as a Cold War Bridging Organization

ERIC Educational Resources Information Center

Elzinga, Aant

2012-01-01

When the journal "Minerva" was founded in 1962, science and higher educational issues were high on the agenda, lending impetus to the interdisciplinary field of "Science Studies" "qua" "Science Policy Studies." As government expenditures for promoting various branches of science increased dramatically on…

Improving recombinant protein purification yield

USDA-ARS?s Scientific Manuscript database

Production of adequate amounts of recombinant proteins is essential for antibody production, biochemical activity study, and structural determination during the post-genomic era. It’s technologically challenging and a limiting factor for tung oil research because analytical reagents such as high qua...

Crop species diversity changes in the United States: 1978-2012

USDA-ARS?s Scientific Manuscript database

Anecdotal accounts regarding reduced US cropping system diversity have raised concerns about negative impacts of increasingly homogeneous cropping systems. However, formal analyses to document such changes are lacking. Using US Agriculture Census data, which is collected on 5-year intervals, we qua...

A ChIP-Seq Data Analysis Pipeline Based on Bioconductor Packages.

PubMed

Park, Seung-Jin; Kim, Jong-Hwan; Yoon, Byung-Ha; Kim, Seon-Young

2017-03-01

Nowadays, huge volumes of chromatin immunoprecipitation-sequencing (ChIP-Seq) data are generated to increase the knowledge on DNA-protein interactions in the cell, and accordingly, many tools have been developed for ChIP-Seq analysis. Here, we provide an example of a streamlined workflow for ChIP-Seq data analysis composed of only four packages in Bioconductor: dada2, QuasR, mosaics, and ChIPseeker. 'dada2' performs trimming of the high-throughput sequencing data. 'QuasR' and 'mosaics' perform quality control and mapping of the input reads to the reference genome and peak calling, respectively. Finally, 'ChIPseeker' performs annotation and visualization of the called peaks. This workflow runs well independently of operating systems (e.g., Windows, Mac, or Linux) and processes the input fastq files into various results in one run. R code is available at github: https://github.com/ddhb/Workflow_of_Chipseq.git.

Being qua becoming: Aristotle's "Metaphysics", quantum physics, and Process Philosophy

NASA Astrophysics Data System (ADS)

Johnson, David Kelley

In Aristotle's First Philosophy, science and philosophy were partners, but with the rise of empiricism, went their separate ways. Metaphysics combined the rational and irrational (i.e. final cause/unmoved mover) elements of existence to equate being with substance, postulating prime matter as pure potential that was actuated by form to create everything. Modern science reveres pure reason and postulates its theory of being by a rigorous scientific methodology. The Standard Model defines matter as energy formed into fundamental particles via forces contained in fields. Science has proved Aristotle's universe wrong in many ways, but as physics delves deeper into the quantum world, empiricism is reaching its limits concerning fundamental questions of existence. To achieve its avowed mission of explaining existence completely, physics must reunite with philosophy in a metascience modeled on the First Philosophy of Aristotle. One theory of being that integrates quantum physics and metaphysics is Process Philosophy.

Analysis of crude oil markets with improved multiscale weighted permutation entropy

NASA Astrophysics Data System (ADS)

Niu, Hongli; Wang, Jun; Liu, Cheng

2018-03-01

Entropy measures are recently extensively used to study the complexity property in nonlinear systems. Weighted permutation entropy (WPE) can overcome the ignorance of the amplitude information of time series compared with PE and shows a distinctive ability to extract complexity information from data having abrupt changes in magnitude. Improved (or sometimes called composite) multi-scale (MS) method possesses the advantage of reducing errors and improving the accuracy when applied to evaluate multiscale entropy values of not enough long time series. In this paper, we combine the merits of WPE and improved MS to propose the improved multiscale weighted permutation entropy (IMWPE) method for complexity investigation of a time series. Then it is validated effective through artificial data: white noise and 1 / f noise, and real market data of Brent and Daqing crude oil. Meanwhile, the complexity properties of crude oil markets are explored respectively of return series, volatility series with multiple exponents and EEMD-produced intrinsic mode functions (IMFs) which represent different frequency components of return series. Moreover, the instantaneous amplitude and frequency of Brent and Daqing crude oil are analyzed by the Hilbert transform utilized to each IMF.

Sulphur stable isotope systematics in diagenetic pyrite from the North Sea hydrocarbon reservoirs revealed by laser combustion analysis.

PubMed

Fallick, Anthony E; Boyce, Adrian J; McConville, Paul

2012-01-01

Our study focuses on pyrite nodules developed in the Brent Group sandstones, which host the Brent Oilfield, one of the North Sea's greatest oil and gas producers. Timing of nodule formation is equivocal, but due to the forceful, penetrative textures that abound, it is considered late. This pyrite offers a research opportunity because it records the development of the supply of H(2)S in a hydrocarbon reservoir and its sulphur isotopic composition. Laser-based analysis of δ(34)S reveals an extraordinary diversity in values and patterns. The values range from-27 to+72‰, covering half the terrestrial range, with large variations at the submillimetre scale. Isotopically heavy (δ(34)S ∼+30‰ or higher) sulphide is endemic, but low δ(34)S pyrite is also present and appears to represent a temporally though not spatially (on the ∼cm scale) distinct pyritisation event. The distribution of δ(34)S values within individual concretions can be normal (Gaussian), but in some cases may reflect progressive isotope fractionation process(es), conceivably of Rayleigh type. The source of the sulphur and the identity of the isotope fractionation process(es) remain enigmatic.

The Challenge to USAFRICOM from Africa’s Colonial Past

DTIC Science & Technology

2010-03-18

build national treasure through colonization and empire building was on. Seven nations—Britain, France, Portugal , Belgium, Germany, Italy and Spain...ability to diminish the local support and sanctuary for terrorists that is the sine qua non of their global reach. • American deeds matter more

Perspectives on barriers to eating healthy among food pantry clients

USDA-ARS?s Scientific Manuscript database

The objective of this study was to explore perspectives on barriers of eating healthy among food pantry clients. Food pantry clients participated in focus groups/interviews. Qualitative data were coded and analyzed using content analyses and grounded theory approach. Themes were then identified. Qua...

EPA'S COASTAL 2000 MONITORING PROGRAM IN THE NORTHEAST U.S.: CONSISTENCY IN METHODS AND QUALITY ASSURANCE

EPA Science Inventory

As part of EPA's national Coastal 2000 effort to estimate the ecological condition of our Nation's estuarine resources, sampling of the estuaries of the northeast United States (Delaware to Maine) began in the summer of 2000. Samples and data were collected to determine water qua...

Multi-model Comparison of Lateral Boundary Contributions to Ozone Concentrations over the United States (CM

EPA Science Inventory

As the National Ambient Air Quality Standards (NAAQS) for ozone become more stringent, there has been growing attention on characterizing the contributions and the uncertainties in ozone from outside the US to the ozone concentrations within the US. The third phase of the Air Qua...

Litter survey : status report 2.

DOT National Transportation Integrated Search

1979-01-01

This report discusses the results of three series of litter pickups at twenty 0.1-mile long sites on Virginia highways 4 sites on the interstate system, and 8 each on the primary and secondary systems. This study is a continuing effort to monitor qua...

Effects of thickness and gain on the amplitude of airborne ultrasonics

USDA-ARS?s Scientific Manuscript database

Currently, hides and leather are visually inspected and ranked for quality, usable area, and sale price. However, visual inspection is not reliable for detecting defects, which are usually hidden inside the material. Development of a non-contact nondestructive method to accurately evaluate the qua...

Thermal remote sensing of crop water status: pros and cons of two different approaches

USDA-ARS?s Scientific Manuscript database

Recent climate change has lead, in many places around the world, to a decrease in the availability of water resources. This limited water availability is decreasing the cost-effectiveness of irrigated agricultural crops, and practices reducing the required amount of water without decreasing the qua...

Analysis of swainsonine and swainsonine N-oxide as trimethylsilyl derivatives by Liquid Chromatography-Mass Spectrometry and their relative occurrence in plants toxic to livestock

USDA-ARS?s Scientific Manuscript database

A liquid chromatography-mass spectrometry method was developed for the analysis of the indolizidine alkaloid swainsonine and its N-oxide. The method is based on a one step solvent partitioning extraction procedure followed by trimethylsilylation of the dried extract and subsequent detection and qua...

Multi-Model Comparison of Lateral Boundary Contributions to Surface Ozone Over the United States

EPA Science Inventory

As the National Ambient Air Quality Standards (NAAQS) for ozone become more stringent, there has been growing attention on characterizing the contributions and the uncertainties in ozone from outside the US to the ozone concentrations within the US. The third phase of the Air Qua...

Multi-model Comparison of Lateral Boundary Contributions to Ozone Concentrations over the United States

EPA Science Inventory

As the National Ambient Air Quality Standards (NAAQS) for ozone become more stringent, there has been growing attention on characterizing the contributions and the uncertainties in ozone from outside the US to the ozone concentrations within the US. The third phase of the Air Qua...

Multi-model Comparison of Lateral Boundary Contributions to Ozone Concentrations over the United States (CMAS Presentation)

EPA Science Inventory

As the National Ambient Air Quality Standards (NAAQS) for ozone become more stringent, there has been growing attention on characterizing the contributions and the uncertainties in ozone from outside the US to the ozone concentrations within the US. The third phase of the Air Qua...

Inconsistencies in Autism-Specific Emotion Interventions: Cause for Concern

ERIC Educational Resources Information Center

Caldeira, Monica; Edmunds, Alan

2012-01-01

Precise educational interventions are the sine qua non of services for students with exceptionalities. Applying interventions riddled with inconsistencies, therefore, interferes with the growth and learning potential of students who need these interventions. This research synthesis documents the inconsistencies revealed during a critical analysis…

Joint Workshop on High Confidence Medical Devices, Software, and Systems (HCMDSS) and Medical Device Plug-and-Play (MD PnP) Interoperability

DTIC Science & Technology

2008-05-01

Giacomo Cabri, Francesco De Mola , Letizia Leonardi University of Modena, ITALY Plug-and-Play and Network-Capable Medical Instrumentation and...Janice Crosby CIMIT Steven Dain University of Western Ontario Francesco De Mola University of Modena and Reggio Emilia Ann Demaree CapsuleTech, Inc. Robert...Jennifer Hou Mu Sun University of Kentucky Brent Seales University of Michigan John Hayes University of Modena and Reggio Emilia Francesco De Mola

Evaluation of the Physiological Challenges in Extreme Environments: Implications for Enhanced Training, Operational Performance and Sex-Specific Responses

DTIC Science & Technology

2016-10-01

Operational Performance and Sex -Specific Responses PRINCIPAL INVESTIGATOR: Brent C. Ruby CONTRACTING ORGANIZATION: The University of Montana System...Environments: Implications for Enhanced Training, Operational Performance and Sex -Specific Responses 5a. CONTRACT NUMBER 5b. GRANT NUMBER W81XWH-15-2-0075...mitochondrial gene responses were not altered by altitude stress. Moreover, there were no differences across sex . While prior research has clearly

Public Private Business Models for Defence Acquisition

DTIC Science & Technology

2014-04-30

Initiatives (PFIs), franchising , concessions, Joint Ventures (JVs) and outright privatisation (Grimsey & Lewis, 2004, p. 54); Off-The-Shelf (OTS...Design (D), Finance (F), Buy (B)/Rent (R)/Lease (L), Construct (C) (Build (B)), Develop (D), Own (O), Operate (O), Manage (M), Maintain (M) and Transfer...Logistics Logistics Infrastructure, and Locistics Other affected None None Equipment Eql..ipment OLoOs Finance- Buy - Desig~ - Buy - Private sector

High Resolution Orientation Imaging Microscopy

DTIC Science & Technology

2012-05-02

Structure of In-Situ Deformations of Steel , TMS, San Diego, 2011 13. Jay Basinger, David Fullwood, Brent Adams, EBSD Detail Extraction for Greater Spatial...Its use has contributed to the development of new steels , aluminum alloys, high TC superconductors, electronic materials, lead-free solders, optical...Resolution The simulated pattern method has been used to recover lattice tetragonality in high-strength low- alloy steels . Since the level of

Adding Nonlinear Tools to the Strategist’s Toolbox

DTIC Science & Technology

2001-06-01

between interests. Idealists base their arguments on the pioneers like Hugo Grotius (1583-1645) and Immanuel Kant (1724-1804). The Idealist school based...12Blupete, [website]: available from http://www.blupete.com/Literature/ Biographies / Philosophy/Popper.htm; Internet. 13Glesne and Peshkin, 24. 39...www.blupete.com/Literature/ Biographies / Philosophy/Popper.htm. Internet. Dean Robbins, Brent. Mythos and Logos. Available from http://www.geocities.com/ Athens

STS-81 pilot Jett on aft flight deck during approach to Mir

NASA Image and Video Library

1997-02-26

STS081-368-011 (12-22 Jan. 1997) --- Astronaut Brent W. Jett, Jr., STS-81 pilot, appears restful and unfazed as Russia's Mir Space Station appears in the window over his shoulder on the Space Shuttle Atlantis' aft flight deck. Following docking of Mir and Atlantis, Jett and his crew mates went on to spend several days sharing experiments and supply-transfer with the Mir-22 crewmembers.

The Navy Biofuel Initiative Under the Defense Production Act

DTIC Science & Technology

2012-06-22

Market for Biomass -Based Diesel Fuel in the Renewable Fuel Standard (RFS), by Brent D. Yacobucci, The Market for Biomass -Based Diesel Fuel in the...defense.17 During the 1970s, DOE directed a synthetic fuels program toward commercializing coal liquefaction, coal gasification , and oil shale... Biomass : Background and Policy, by Anthony Andrews and Jeffrey Logan. The Navy Biofuel Initiative Under the Defense Production Act Congressional

Overlay metrology for double patterning processes

NASA Astrophysics Data System (ADS)

Leray, Philippe; Cheng, Shaunee; Laidler, David; Kandel, Daniel; Adel, Mike; Dinu, Berta; Polli, Marco; Vasconi, Mauro; Salski, Bartlomiej

2009-03-01

The double patterning (DPT) process is foreseen by the industry to be the main solution for the 32 nm technology node and even beyond. Meanwhile process compatibility has to be maintained and the performance of overlay metrology has to improve. To achieve this for Image Based Overlay (IBO), usually the optics of overlay tools are improved. It was also demonstrated that these requirements are achievable with a Diffraction Based Overlay (DBO) technique named SCOLTM [1]. In addition, we believe that overlay measurements with respect to a reference grid are required to achieve the required overlay control [2]. This induces at least a three-fold increase in the number of measurements (2 for double patterned layers to the reference grid and 1 between the double patterned layers). The requirements of process compatibility, enhanced performance and large number of measurements make the choice of overlay metrology for DPT very challenging. In this work we use different flavors of the standard overlay metrology technique (IBO) as well as the new technique (SCOL) to address these three requirements. The compatibility of the corresponding overlay targets with double patterning processes (Litho-Etch-Litho-Etch (LELE); Litho-Freeze-Litho-Etch (LFLE), Spacer defined) is tested. The process impact on different target types is discussed (CD bias LELE, Contrast for LFLE). We compare the standard imaging overlay metrology with non-standard imaging techniques dedicated to double patterning processes (multilayer imaging targets allowing one overlay target instead of three, very small imaging targets). In addition to standard designs already discussed [1], we investigate SCOL target designs specific to double patterning processes. The feedback to the scanner is determined using the different techniques. The final overlay results obtained are compared accordingly. We conclude with the pros and cons of each technique and suggest the optimal metrology strategy for overlay control in double

CHARACTERIZING PIPE WALL DEMAND: IMPLICATIONS FOR WATER QUALITY MODELING

EPA Science Inventory

It has become generally accepted that water quality can deteriorate in a distribution system through reactions in the bulk phase and/or at the pipe wall. These reactions may be physical, chemical or microbiological in nature. Perhaps one of the most serious aspects of water qua...

US EPA GLOBAL POSITIONING SYSTEMS - TECHNICAL IMPLEMENTATION GUIDANCE

EPA Science Inventory

The U.S. EPA Geospatial Quality Council (GQC) was formed in 1998 to provide Quality Assurance guidance for the development, use, and products of geospatial activities and research. The long-term goals of the GQC are expressed in a living document, currently the EPA Geospatial Qua...

ORGANIC EMISSIONS FROM AUTOMOBILE INTERIORS

EPA Science Inventory

The report gives results of an evaluation of six subcompact automobiles for the emission of vinyl chloride monomer (VCM) and other organics into the passenger compartment. Evaluated were a Ford Pinto, AMC Gremlin, GMC Vega, GMC Chevette, NMC Datsun 710, and VW Rabbit. VCM was qua...

Evaluating analytic and risk assessment tools to estimate sediment and nutrients losses from agricultural lands in the southern region of the USA

USDA-ARS?s Scientific Manuscript database

Non-point source pollution from agricultural fields is a critical problem associated with water quality impairment in the USA and a low-oxygen environment in the Gulf of Mexico. The use, development and enhancement of qualitative and quantitative models or tools for assessing agricultural runoff qua...

Characteristics of lipids and their feeding value in swine diets

USDA-ARS?s Scientific Manuscript database

In livestock diets, energy is one of the most expensive nutritional components of feed formulation. Because lipids are a concentrated energy source, inclusion of lipids are known to affect growth rate and feed efficiency, but are also known to affect diet palatability, feed dustiness, and pellet qua...

Selection for Reduced Fusarium Ear Rot and Fumonisin Content in Advanced Backcross Maize Lines and Their Topcross Hybrids

USDA-ARS?s Scientific Manuscript database

Backcross breeding is an important method to improve elite cultivars for traits controlled by a small number of loci but has been used less frequently to improve quantitatively controlled traits. Resistances to Fusarium ear rot and contamination by the associated mycotoxin fumonisin in maize are qua...

Recycling of ligno-cellulosic and polythylene wastes from agricultural operations in thermoplastic composites

USDA-ARS?s Scientific Manuscript database

In the US, wood plastic composites (WPC) represent one of the successful markets for natural fiber-filled thermoplastic composites. In the past several years, the availability of good quality wood fiber has been diminishing and prices of wood and plastic have been increasing. Therefore, the vast qua...

INDUCTION OF DNA ADDUCTS, TUMORS, AND KI-RAS ONCOGENE MUTATIONS IN STRAIN A/J MOUSE LUNG BY IP. ADMINISTRATION OF DIBENZ[A,H]ANTHRACENE

EPA Science Inventory

Induction of DNA adducts, tumors, and Ki-ras oncogene mutations in strain AlJ mouse lung by ip. administration of dibenz[a,h]anthracene

Previous studies of polycyclic aromatic hydrocarbon (P AH) induced lung tumors in the strain NJ mouse model system have demonstrated qua...

A ChIP-Seq Data Analysis Pipeline Based on Bioconductor Packages

PubMed Central

Park, Seung-Jin; Kim, Jong-Hwan; Yoon, Byung-Ha; Kim, Seon-Young

2017-01-01

Nowadays, huge volumes of chromatin immunoprecipitation-sequencing (ChIP-Seq) data are generated to increase the knowledge on DNA-protein interactions in the cell, and accordingly, many tools have been developed for ChIP-Seq analysis. Here, we provide an example of a streamlined workflow for ChIP-Seq data analysis composed of only four packages in Bioconductor: dada2, QuasR, mosaics, and ChIPseeker. ‘dada2’ performs trimming of the high-throughput sequencing data. ‘QuasR’ and ‘mosaics’ perform quality control and mapping of the input reads to the reference genome and peak calling, respectively. Finally, ‘ChIPseeker’ performs annotation and visualization of the called peaks. This workflow runs well independently of operating systems (e.g., Windows, Mac, or Linux) and processes the input fastq files into various results in one run. R code is available at github: https://github.com/ddhb/Workflow_of_Chipseq.git. PMID:28416945

Exploiting long read sequencing technologies to establish high quality highly contiguous pig reference genome assemblies

USDA-ARS?s Scientific Manuscript database

The current pig reference genome sequence (Sscrofa10.2) was established using Sanger sequencing and following the clone-by-clone hierarchical shotgun sequencing approach used in the public human genome project. However, as sequence coverage was low (4-6x) the resulting assembly was only of draft qua...

Rethinking Discussions of Justice in Educational Research: Formative Justice, Educational Liberalism, and Beyond

ERIC Educational Resources Information Center

Thompson, Winston C.

2016-01-01

Background/Context: Educational research tends to borrow accounts of justice from scholarship embedded within the structures and commitments of other disciplines or fields of study. This has created a body of educational research that largely responds to the "justice" goals of those disciplines rather than education qua education.…

Design and performance of recirculating systems for Atlantic salmon (Salmo salar) at the USDA ARS National Cold Water Marine Aquaculture Center (Franklin, Maine)

USDA-ARS?s Scientific Manuscript database

Atlantic salmon cultured in the NCWMAC breeding program have grown well in the fish culture systems during the first 3 years of operation. The systems were operated at approximately 98% reuse (2% makeup water on the basis of flow rate). The water recirculating systems maintained acceptable water qua...

A clade-specific Arabidopsis gene connects primary metabolism and senescence

USDA-ARS?s Scientific Manuscript database

Plants have to deal with environmental insults as they cannot move to escape from stressful conditions. To do so, they have evolved novel components that respond to the changing environments. A primary example is Qua Quine Starch (QQS, AT3G30720), an Arabidopsis thaliana-specific (orphan) gene that ...

The QQS orphan gene regulates carbon and nitrogen partitioning across species via NF-YC interactions

USDA-ARS?s Scientific Manuscript database

The allocation of carbon and nitrogen resources to the synthesis of plant proteins, carbohydrates, and lipids is complex and under the control of many genes; much remains to be understood about this process. QQS (Qua Quine Starch, At3g30720), an orphan gene unique to Arabidopsis thaliana, regulates...

CONSTELLATION Images from other centers - February 2010

NASA Image and Video Library

2010-02-08

JSC2010-E-019040 (8 Feb. 2010) --- Brent Jett, director, flight crew operations, watches a monitor at his console in the space shuttle flight control room in the Mission Control Center at NASA's Johnson Space Center during launch countdown activities a few hundred miles away in Florida, site of space shuttle Endeavour's STS-130 launch. John McCullough (seated), chief of the flight director office, is at right.

AcceleDent as a Means for Pain Reduction During Orthodontic Treatment

DTIC Science & Technology

2015-05-30

AcceleDent as a Means for Pain Reduction During Orthodontic Treatment Wendy D. Lobre APPROVED: Brent Callegari, Supervising Pro ssor and Program...entitled: "AcceleDent as a Means for Pain Reduction During Orthodontic Treatment" is appropriately acknowledged and beyond brief excerpts is with the...Those in Harms Way AcceleDent as a Means for Pain Reduction During Orthodontic Treatment TITLE PAGE A THESIS Presented to the Faculty of Uniform

Unmanned Aircraft System / Remotely Piloted Aircraft (UAS/RPA) Human Factors and Human Systems Integration Research Workshop Held in Dayton, Ohio on November 8-9, 2011

DTIC Science & Technology

2012-05-25

station design . These issues include: poor ergonomics ; varying data input methods; multiple inputs required to implement a single command; lack of...facing the UAS/RPA discipline. Major discussion topics included: UAS operator selection, training, control station design , manpower and scheduling...Break 1400 – 1430: Naval UAS Training  LCDR Brent Olde 1430 – 1500: Control Station Design Issues  Melissa Walwanis 1500 – 1600: Tour of NAMRU-D

Iraq: Post-Saddam Governance and Security

DTIC Science & Technology

2008-10-02

the Ottoman empire after British forces defeated the Ottomans in World War I and took control of the territory in 1918 . Britain had tried to take Iraq... Religions Freedom Report, September 2007; DOD Measuring Stability Report, September 2008. CRS-3 1 Bush, George H.W., and Brent Scowcroft. A World...politically. Similarly, the September 19, 2008 report on International Religious Freedom attributed restrictions on the free exercise of religion (by

Assessing Post Conflict State Building Efforts

DTIC Science & Technology

2013-03-01

Develop a global partnership for development Target: Develop further an open, rule-based, predictable, non-discriminatory trading and finance system...Beginner’s Guide to Nation-Building (Santa Monica, CA: Rand Corporation ), 2007, xvii. 15 Samuel Berger, Brent Scowcroft, and William L. Nash, “In...The Beginner’s Guide, xxi. 25 Richard A. Berk and Peter H. Rossi, Thinking About Program Evaluation 2, (Thousand Oaks, CA: Sage Publications, 1999

The Efficacy of Group Decision Support Systems: A Field Experiment to Evaluate Impacts on Air Force Decision Makers

DTIC Science & Technology

1992-12-01

made several interesting observations as well. Gray, Vogel, and Beauclair developed an alternate method for determining which experiments were similar...organization" ( Beauclair , 1989), (1:329, 331). 2.7 Summary of Existing Research In the book Group Support Systems: New Perspectives," Alan Dennis and Brent...Computer TDY Temporary Duty USAF United States Air Force VIF Variance Inflation Factor P-2 Bibliography 1. Beauclair , Renee A. "An Experimental Study of

A Look inside the Fourth-Grade Reading Classroom. Policy Notes. Volume 18, Number 3, Fall 2010

ERIC Educational Resources Information Center

Coley, Richard J.

2010-01-01

What happens behind classroom doors--the content, experiences, and interactions with teachers that students encounter--is the "sine qua non" of student classroom learning. But everyone's inventory of instructional practices across different subjects and grades is limited; and the same can be said about everyone's knowledge of what makes for good…

Language Policy Provisions and Curriculum Issues: The Challenges for Secondary Schools in Nigeria

ERIC Educational Resources Information Center

Adejimola, Amuseghan Sunday

2010-01-01

Language, language policy and curriculum issues occupy very important and strategic places in educational planning in any society. In a multilingual Nigerian society as well as in similar countries like Australia, India or even in seemingly homogeneous linguistic societies like Britain, language planning, development and policies are sin qua non.…

Philosophy Because the World Matters

ERIC Educational Resources Information Center

Reeve, Hester

2017-01-01

"Philosophy Because the World Matters" promotes a valorization of philosophy as a practice able to activate an individual's relationship making to "having a life" and, in turn, to allow the unfolding self-illumination (qua onto-ethical capacity) to effect a constructive world-thinking and hence world-building with others. These…

Internship in Vocational Education and Training: Stakeholders' Perceptions of Its Organisation

ERIC Educational Resources Information Center

Akomaning, Edward; Voogt, Joke M.; Pieters, Jules M.

2011-01-01

Polytechnic education in Ghana is an offshoot of technical and vocational education and training, which makes internship a sine qua non for its students. The implementation of internships in the departments of hotel catering and institutional management in Ghanaian polytechnics is examined in this study. The perceptions of the stakeholders suggest…

The Interplay between Text-Based Vocabulary Size and Reading Comprehension of Turkish EFL Learners

ERIC Educational Resources Information Center

Güngör, Fatih; Yayli, Demet

2016-01-01

Reading is an indispensable skill for learners who desire success throughout their academic lives, and vocabulary knowledge is a sine qua non companion of reading comprehension. Despite being inextricably related entities, very little has been written about the necessary vocabulary coverage to understand an expository text and its equivalent in…

Scale of Professional Ethics for Individuals Working in the Field of Special Education: Validity and Reliability Study

ERIC Educational Resources Information Center

Akcamete, Gonul; Kayhan, Nilay; Yildirim, A. Emel Sardohan

2017-01-01

Professional ethics includes the principles set forth by professional associations and accepted as correct by discussions over time, and which has become the sine qua non of a profession today. Professional ethics are established to increase the quality of professional practices and ensure correct and honest conduct. Not having professional…

Better the Devil You See, than the One You Don't: Bearing Witness to Emboldened En-Whitening Epistemology in the Trump Era

ERIC Educational Resources Information Center

Matias, Cheryl E.; Newlove, Peter M.

2017-01-01

Critical scholars of race maintain that racism that is not clearly seen every day is the most dangerous kind. Notwithstanding "invisible" racism qua racism without racists--per some race scholars--explorations on mechanisms of Whiteness in the Trump era must be had. One mechanism is perpetuating epistemological racial ignorance. However,…

Contexts for Teacher Practice: (Re)Considering the Role of Context in Interventions in Early Childhood Teacher Engagement with New Approaches to Shared Book Reading

ERIC Educational Resources Information Center

Delaney, Katherine K.; Neuman, Susan B.

2016-01-01

Although the randomized controlled trial has been regarded as the "sine qua non" in recent years, we argue that understanding contexts for teacher practice is a critical factor in the implementation of intervention, but has often been overlooked in educational research design. In this paper, we argue that randomized trials may not be…

Relationship among Demographic Variables and Pupils' Reasoning Ability

ERIC Educational Resources Information Center

Tella, Adeyinka; Tella, Adedeji; Adika, L. O.; Toyobo, Majekodunmi Oluwole

2008-01-01

Introduction: Pupils reasoning ability is a sine-qua-non to the evaluation of their performance in learning and an indicator of their potential predictors of future performance. Method: The study examined the relationship among demographic variables and reasoning ability of primary school pupils. It drew four hundred pupils from ten (10)…

USING A FISH INDEX TO ASSESS HABITAT QUALITY IN NARRAGANSETT BAY, RHODE ISLAND

EPA Science Inventory

We developed an estuarine index of biotic integrity to assess habitat quality in Narragansett Bay, Rhode Island. Fish were collected at 18 fixed stations with a 61-m x 3.05-m beach seine once per month in July and August from 1988 to 1999. Stations were designated high or low qua...

How Developments in Psychology and Technology Challenge Validity Argumentation

ERIC Educational Resources Information Center

Mislevy, Robert J.

2016-01-01

Validity is the sine qua non of properties of educational assessment. While a theory of validity and a practical framework for validation has emerged over the past decades, most of the discussion has addressed familiar forms of assessment and psychological framings. Advances in digital technologies and in cognitive and social psychology have…

Coyote and Raven (P)re-Visit Environmental Education, Sustainability, and Run-Away Capitalism

ERIC Educational Resources Information Center

Cole, Peter; O'Riley, Pat

2010-01-01

Together with ubiquitous agent evocateurs, Coyote and Raven, the authors engage trickster discourse and narrative shape shifting as they share research protocols and community conversations based on their research with the four Lower Stl'atl'imx communities (Xa'xtsa, N'Quat'qua, Skatin and Samahquam First Nations) of British Columbia, Canada, in…

Investigation Faculty of Education Students' Cyberloafing Behaviors in Terms of Various Variables

ERIC Educational Resources Information Center

Arabaci, I. Bakir

2017-01-01

Today, internet-based information technologies are sine qua non of effective learning and teaching. By the use of multiple multi-media tools in education, learning environment is enriched, persistence of learning is ensured and the boringness of the course is prevented. However, the purposeless use of internet in classrooms leads students to get…

Teachers' Awareness and Usage of Non-Violent Strategies for the Maintenance of Discipline in Nigerian Secondary Schools: A Situational Analysis

ERIC Educational Resources Information Center

Uzoechina, Gladys Oby; Oguegbu, Adaeze; Akachukwu, Esther; Nwasor, Victor Chekume

2015-01-01

This study sought to determine teachers' level of awareness and usage of non-violent strategies/interventions for the maintenance of discipline in secondary schools in Anambra State, Nigeria. Corporal punishment has become an unwritten sine qua non for the maintenance of school discipline--often the first thought that comes to the minds of…

Accuracy in Student Self-Assessment: Directions and Cautions for Research

ERIC Educational Resources Information Center

Brown, Gavin T. L.; Andrade, Heidi L.; Chen, Fei

2015-01-01

Student self-assessment is a central component of current conceptions of formative and classroom assessment. The research on self-assessment has focused on its efficacy in promoting both academic achievement and self-regulated learning, with little concern for issues of validity. Because reliability of testing is considered a sine qua non for the…

Mir 22 and STS-81 crew work with gyrodyne

NASA Image and Video Library

1997-02-04

STS081-301-031 (12-22 Jan 1997) --- Shortly after docking of the Space Shuttle Atlantis and Russia's Mir Space Station, crew members from the respective spacecraft begin to transfer hardware from the Spacehab Double Module (DM) onto the Mir complex. Here, cosmonaut Valeri G. Korzun, Mir-22 commander, along with astronauts Michael A. Baker, commander, and Brent W. Jett, Jr., pilot, unstow a gyrodyne, device for attitude control, transfer to Mir.

STS-81 Mission Highlights Resource Tape

NASA Technical Reports Server (NTRS)

1997-01-01

The flight crew of the STS-81 Space Shuttle Orbiter Atlantis Commander Michael A. Baker, Pilot Brent W. Jett Jr., and Mission Specialists, John M. Grunsfeld, Marsha S. Ivins, Peter J.K. Wisoff, and John M. Linenger present an overview of their mission. Video footage includes the following: prelaunch and launch activities, the crew eating breakfast, shuttle launch, on orbit activities, rendezvous with Mir, Shuttle/Mir joint activities, undocking, and the shuttle landing.

Iraq: Post-Saddam Governance and Security

DTIC Science & Technology

2008-08-12

took control of the territory in 1918 . Britain had tried to take Iraq from the Ottomans earlier in World War I but were defeated at Al Kut in 1916... Religions Freedom Report, September 2007; DOD Measuring Stability Report, June 2008. CRS-3 1 Bush, George H.W., and Brent Scowcroft. A World Transformed...Armenia, Slovakia, Denmark, El Salvador, Ukraine, Romania , Lithuania, Latvia, Mongolia, and Kazakhstan. Polish forces number 900, down from a high

STS-115 crew portrait

NASA Image and Video Library

2002-11-08

STS115-S-002 (8 November 2002) --- These six astronauts take a break from training to pose for the STS-115 crew portrait. Astronauts Brent W. Jett, Jr. (right) and Christopher J. Ferguson, commander and pilot, respectively, flank the mission insignia. The mission specialists are, from left to right, astronauts Heidemarie M. Stefanyshyn-Piper, Joseph R. (Joe) Tanner, Daniel C. Burbank, and Steven G. MacLean, who represents the Canadian Space Agency.

Human subjects protections in community-engaged research: a research ethics framework.

PubMed

Ross, Lainie Friedman; Loup, Allan; Nelson, Robert M; Botkin, Jeffrey R; Kost, Rhonda; Smith, George R; Gehlert, Sarah

2010-03-01

In the 30 years since the Belmont Report, the role of the community in research has evolved and has taken on greater moral significance. Today, more and more translational research is being performed with the active engagement of individuals and communities rather than merely upon them. This engagement requires a critical examination of the range of risks that may arise when communities become partners in research. In attempting to provide such an examination, one must distinguish between established communities (groups that have their own organizational structure and leadership and exist regardless of the research) and unstructured groups (groups that may exist because of a shared trait but do not have defined leadership or internal cohesiveness). In order to participate in research as a community, unstructured groups must develop structure either by external means (by partnering with a Community-Based Organization) or by internal means (by empowering the group to organize and establish structure and leadership). When groups participate in research, one must consider risks to well-being due to process and outcomes. These risks may occur to the individual qua individual, but there are also risks that occur to the individual qua member of a group and also risks that occur to the group qua group. There are also risks to agency, both to the individual and the group. A 3-by-3 grid including 3 categories of risks (risks to well-being secondary to process, risks to well-being secondary to outcome and risks to agency) must be evaluated against the 3 distinct agents: individuals as individual participants, individuals as members of a group (both as participants and as nonparticipants) and to communities as a whole. This new framework for exploring the risks in community-engaged research can help academic researchers and community partners ensure the mutual respect that community-engaged research requires.

Accurate reconstruction of viral quasispecies spectra through improved estimation of strain richness

PubMed Central

2015-01-01

Background Estimating the number of different species (richness) in a mixed microbial population has been a main focus in metagenomic research. Existing methods of species richness estimation ride on the assumption that the reads in each assembled contig correspond to only one of the microbial genomes in the population. This assumption and the underlying probabilistic formulations of existing methods are not useful for quasispecies populations where the strains are highly genetically related. The lack of knowledge on the number of different strains in a quasispecies population is observed to hinder the precision of existing Viral Quasispecies Spectrum Reconstruction (QSR) methods due to the uncontrolled reconstruction of a large number of in silico false positives. In this work, we formulated a novel probabilistic method for strain richness estimation specifically targeting viral quasispecies. By using this approach we improved our recently proposed spectrum reconstruction pipeline ViQuaS to achieve higher levels of precision in reconstructed quasispecies spectra without compromising the recall rates. We also discuss how one other existing popular QSR method named ShoRAH can be improved using this new approach. Results On benchmark data sets, our estimation method provided accurate richness estimates (< 0.2 median estimation error) and improved the precision of ViQuaS by 2%-13% and F-score by 1%-9% without compromising the recall rates. We also demonstrate that our estimation method can be used to improve the precision and F-score of ShoRAH by 0%-7% and 0%-5% respectively. Conclusions The proposed probabilistic estimation method can be used to estimate the richness of viral populations with a quasispecies behavior and to improve the accuracy of the quasispecies spectra reconstructed by the existing methods ViQuaS and ShoRAH in the presence of a moderate level of technical sequencing errors. Availability http://sourceforge.net/projects/viquas/ PMID:26678073

Institutional Mission vs Policy Constraint?: Unlocking Potential

ERIC Educational Resources Information Center

Hazelkorn, Ellen

2005-01-01

The research-intensive and competitive knowledge society is putting HEIs (higher education institutions) under the spotlight. While many HEIs around the world do not proclaim or wish to be research-intensive institutions the majority desire to intensify their research activity because it is seen as a sine qua non of higher education. Accordingly,…

The Instructional Quality Inventory. I. Introduction and Overview

DTIC Science & Technology

1978-11-01

level objectives, "hands-on" performance tests are usually most appropriate. T IS PAQ IS BEST QUA After a test item is consistent with its objective, the...idea. When the statement is separated, the key points stand out, and are not buried in the presentation. There are several ways to accomplish this goal

Developing Pedagogical Competence: Issues and Implications for Marketing Education

ERIC Educational Resources Information Center

Madhavaram, Sreedhar; Laverie, Debra A.

2010-01-01

Competence in pedagogy and research is the sine qua non of marketing educators' careers. However, there is evidence in the literature that marketing academics focus "more on" and "are more competent" in research than teaching. This imbalance, in a majority of instances, can be traced back to doctoral education. Doctoral programs in marketing are…

Enhanced functional properties of tannic acid after thermal hydrolysis

USDA-ARS?s Scientific Manuscript database

Thermal hydrolysis processing of fresh tannic acid was carried out in a closed reactor at four different temperatures (65, 100, 150 and 200°C). Pressures reached in the system were 1.3 and 4.8 MPa at 150 and 200°C, respectively. Hydrolysis products (gallic acid and pyrogallol) were separated and qua...

All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsins

PubMed Central

Hochbaum, Daniel R.; Zhao, Yongxin; Farhi, Samouil L.; Klapoetke, Nathan; Werley, Christopher A.; Kapoor, Vikrant; Zou, Peng; Kralj, Joel M.; Maclaurin, Dougal; Smedemark-Margulies, Niklas; Saulnier, Jessica L.; Boulting, Gabriella L.; Straub, Christoph; Cho, Yong Ku; Melkonian, Michael; Wong, Gane Ka-Shu; Harrison, D. Jed; Murthy, Venkatesh N.; Sabatini, Bernardo; Boyden, Edward S.; Campbell, Robert E.; Cohen, Adam E.

2014-01-01

All-optical electrophysiology—spatially resolved simultaneous optical perturbation and measurement of membrane voltage—would open new vistas in neuroscience research. We evolved two archaerhodopsin-based voltage indicators, QuasAr1 and 2, which show improved brightness and voltage sensitivity, microsecond response times, and produce no photocurrent. We engineered a novel channelrhodopsin actuator, CheRiff, which shows improved light sensitivity and kinetics, and spectral orthogonality to the QuasArs. A co-expression vector, Optopatch, enabled crosstalk-free genetically targeted all-optical electrophysiology. In cultured neurons, we combined Optopatch with patterned optical excitation to probe back-propagating action potentials in dendritic spines, synaptic transmission, sub-cellular microsecond-timescale details of action potential propagation, and simultaneous firing of many neurons in a network. Optopatch measurements revealed homeostatic tuning of intrinsic excitability in human stem cell-derived neurons. In brain slice, Optopatch induced and reported action potentials and subthreshold events, with high signal-to-noise ratios. The Optopatch platform enables high-throughput, spatially resolved electrophysiology without use of conventional electrodes. PMID:24952910

STS-132/ULF4 WFCR Flight Controllers on Console

NASA Image and Video Library

2010-05-14

JSC2010-E-080463 (14 May 2010) --- Brent Jett, director, flight crew operations, is pictured in the space shuttle flight control room in the Mission Control Center at NASA's Johnson Space Center during launch countdown activities a few hundred miles away in Florida, site of space shuttle Atlantis' scheduled STS-132 launch. Liftoff was on time at 2:20 p.m. (EDT) on May 14, 2010 from launch pad 39A at NASA's Kennedy Space Center.

STS-132/ULF4 WFCR Flight Controllers on Console

NASA Image and Video Library

2010-05-14

JSC2010-E-080460 (14 May 2010) --- Brent Jett, director, flight crew operations; and flight director Norm Knight (foreground) watch a monitor in the space shuttle flight control room in the Mission Control Center at NASA's Johnson Space Center during the launch of space shuttle Atlantis a few hundred miles away in Florida. Liftoff was on time at 2:20 p.m. (EDT) on May 14, 2010 from launch pad 39A at NASA's Kennedy Space Center.

STS-97 Crew Activity Report/Flight Day 10 Highlights

NASA Technical Reports Server (NTRS)

2000-01-01

On this tenth day of the STS-97 mission, Commander Brent W. Jett, Pilot Michael J. Bloomfield, and Mission Specialists Joseph R. Tanner, Carlos I. Noriega, and Marc Garneau are seen saying good-bye to the International Space Station's (ISS's) resident crew (Commander Bill Shepherd, Pilot Yuri Gidzenko and Flight Engineer Sergei Krikalev) and sealing the hatches between the Endeavour Orbiter and the ISS. Footage shows the ISS against a rotating Earth as it passes over China.

Consolidating Air Force Maintenance Occupational Specialties

DTIC Science & Technology

2016-01-01

Bill Gilbert . A number of colleagues at RAND, including John Drew, Laura Baldwin, Al Robbert, and Ray Conley, provided support during this effort...Massey, James M. Masters, Raymond A. Pyles, Ricardo Sanchez, Jerry M. Sollinger, Brent Thomas, Robert S. Tripp, and Ben D. Van Roo, Analysis of the Air...MG-872-AF, 2009), Tripp et al. (Robert S. Tripp, Ronald G. McGarvey, Ben D. Van Roo, James M. Masters and Jerry M. Sollinger. A Repair Network

Environmental Assessment for Construction and Repair of Fuel Storage and Offloading Facilities at Kirtland Air Force Base

DTIC Science & Technology

2005-09-01

G Ot-T GOO) D. BRENT WILSON, P.E. Base Civil Engineer Kirtland Air Force Base Kirtland AFB Fuel Storage and Ofjloading Facilities Construction...September 2005 A-1 3 77 MSG/CEVQ DEPARTMENT OF THE AIR FORCE 3 77th Civil Engineer Division (AFMC) 2050 Wyoming Blvd SE, Suite 120 Kirtland AFB NM...FINAL FINDING OF NO SIGNIFICANT IMPACT FOR THE FOR CONSTRUCTION AND REP AIR OF FUEL STORAGE AND OFFLOADING FACILITIES AT KIRTLAND AIR FORCE

KSC-06pd0637

NASA Image and Video Library

2006-04-14

JOHNSON SPACE CENTER, TX - STS115-S-002 (November 8, 2002) -- These six astronauts take a break from training to pose for the STS-115 crew portrait. Astronauts Brent W. Jett Jr. (right) and Christopher J. Ferguson, command and pilot respectively, flank the mission insignia. The mission specialists are, from left to right, astronauts Heidemarie M. Stefanyshyn-Piper, Joseph R. (Joe) Tanner, Daniel C. Burbank, and Steven G. MacLean, who represents the Canadian Space Agency.

The Overselling of Higher Education

ERIC Educational Resources Information Center

Leef, George C.

2006-01-01

There is not enough substance behind a degree to warrant the ubiquitous belief that a stint in higher education is a "sine qua non" for success in America. While college diplomas may translate into higher-paying jobs for some, high school signifies little in the way of education these days, so jaded employers' estimates of the real value of…

Parents' Rights and Educational Provision

ERIC Educational Resources Information Center

Marples, Roger

2014-01-01

Legitimate parental interests need to be distinguished from any putative rights parents "qua" parents may be said to possess. Parents have no right to insulate their children from conceptions of the good at variance with those of their own. Claims to the right to faith schools, private schools, home-schooling or to withdraw a child from…

Promoting the Reading Culture Towards Human Capital and Global Development

ERIC Educational Resources Information Center

Olasehinde, M. O.; Akanmode, O. A.; Alaiyemola, A. T.; Babatunde, O. T.

2015-01-01

It is commonly agreed that a country cannot be fully developed without large-scale investment in her educational scheme since the breakthrough of a country is directly proportional to her educational level. Since the acquisition of effective reading skills has a positive effect on all school subjects, then reading is sine-qua-non for human capital…

Enacting Attention: Concentration and Shared Focus in Montessori Classrooms

ERIC Educational Resources Information Center

Epstein, Paul

2012-01-01

Concentration is a "sine qua non," a hallmark, of a Montessori Casa program. Yet, it happens that some children do not concentrate. They do not engage with the materials in the classic pattern of normalization. They are not challenged by ADD, ADHD, or a variant of sensory integration spectrum disorder. Instead of working alone, they prefer the…

Federal Government Funding of Research in Universities in Nigeria, the University of Benin as a Case Study

ERIC Educational Resources Information Center

Osagie, Roseline O.

2012-01-01

It is increasingly evident that research is extremely critical and important if universities are to serve as engines of development in their areas of locations. For a knowledge-driven world, investment in research and development (R&D) is a sine qua non for a nation. Few studies have examined the federal government's investment in research in…

Effects of marketing group on the variability of fresh loin, belly, and fresh and processed ham quality from pigs sourced from a commercial processing facility

USDA-ARS?s Scientific Manuscript database

The objective was to quantify the effect of marketing group (MG) on the variability of primal quality. Pigs (N=7,684) were slaughtered in 3 MGs from 8 barns. Pigs were from genetic selection programs focused on lean growth (L; group 1 n=1,131; group 2 n=1,466; group 3 n=1,030) or superior meat qua...

The Socially Situated Dynamics of Children's Learning Processes in Classrooms: What Do We Learn from a Complex Dynamic Systems Approach?

ERIC Educational Resources Information Center

Steenbeek, Henderien; van Vondel, Sabine; van Geert, Paul

2017-01-01

This article concentrates on the question what kind of model--conceptual and statistical--can serve as a good working model for the study of learning and teaching processes qua processes. We claim that a good way of answering this question is to begin by observing a teaching and learning process as, where, and when it occurs. In addition, a…

Historical Change of Equilibrium Water Temperature in Japan

NASA Astrophysics Data System (ADS)

Miyamoto, H.

2015-12-01

Changes in freshwater ecosystems due to a climate change have been great concern for sustainable river basin management both for water resources utilization and ecological conservation. However, their impact seems to be difficult to evaluate because of wide variety of basin characteristics along a river network both in nature and social environment. This presentation uses equilibrium water temperature as a simple criterion index for evaluating the long-term changes of stream thermal environment due to the historical climate change in Japan. It examines, at first, the relationship between the equilibrium water temperature and the stream temperature observed for 7 years at a lower reach in the Ibo River, Japan. It analyzes, then, the seasonal and regional trends of the equilibrium water temperature change for the last 50 years at 133 meteorological station sites throughout Japan, discussing their rising or falling characteristics. The correlation analysis at the local reach of the Ibo River shows that the equilibrium water temperature has similar trend of change as the stream temperature. However, its value tends to be higher than the stream temperature in summer, while lower in winter. The onset of the higher equilibrium water temperature fluctuates annually from mid February to early April. This onset fluctuation at each spring could be influenced by the different amount of snow at the antecedent winter. The rising or falling trends of the equilibrium water temperature are analyzed both annually and seasonally through the regression analysis of the 133 sites in Japan. Consequently, the trends of the temperature change could be categorized by 12 patterns. As for the seasonal analysis, the results shows that there are many sites indicating the falling trend in spring and summer, and rising trends in autumn and winter. In particular, winter has the strong rising tendency throughout Japan. As for the regional analysis, the result illustrates the precise rationality; e

STS-132/ULF4 WFCR Flight Controllers on Console

NASA Image and Video Library

2010-05-14

JSC2010-E-080409 (14 May 2010) --- Brent Jett (left), director, flight crew operations; and flight director Norm Knight are pictured in the space shuttle flight control room in the Mission Control Center at NASA's Johnson Space Center during launch countdown activities a few hundred miles away in Florida, site of space shuttle Atlantis' scheduled STS-132 launch. Liftoff was on time at 2:20 p.m. (EDT) on May 14, 2010 from launch pad 39A at NASA's Kennedy Space Center.

STS-72 Flight Day 9

NASA Technical Reports Server (NTRS)

1996-01-01

On this ninth day of the STS-72 mission, the flight crew, Cmdr. Brian Duffy, Pilot Brent W. Jett, and Mission Specialists Leroy Chiao, Daniel T. Barry, Winston E. Scott, and Koichi Wakata (NASDA), awakened to music from the movie Star Wars. The astronauts conducted a news conference via satellite and answered questions from both Japanese and U.S. reporters at the Kennedy Space Center and the Johnson Space Center. The preparation for the scheduled night landing continues from the previous day's activities.

Thomas Merton Goes to Class: Pedagogy on the Borders of the Short Story

ERIC Educational Resources Information Center

Callaghan, Michael J.

2011-01-01

Our thesis is more finely tuned to Thomas Merton (1915-68) the writer, more specifically, the poet/artist/writer and thinker. These are the components of the "Merton" voice. Merton senses the quality of innocence as the "sine qua non" of the poet or writer's vocation: "His art depends on an ingrained innocence which he would lose in business, in…

Measurement Theory in Language Testing: Past Traditions and Current Trends

ERIC Educational Resources Information Center

Salmani-Nodoushan, Mohammad Ali

2009-01-01

A good test is one that has at least three qualities: reliability, or the precision with which a test measures what it is supposed to measure; validity, i.e., if the test really measures what it is supposed to measure, and practicality, or if the test, no matter how sound theoretically, is practicable in reality. These are the sine qua non for any…

Normative and scientific approaches to the understanding and evaluation of art.

PubMed

Gilmore, Jonathan

2013-04-01

The psycho-historical framework proposes that appreciators' responses to art vary as a function of their sensitivity to its historical dimensions. However, the explanatory power of that framework is limited insofar as it assimilates relevantly different kinds of appreciation and insofar as it eschews a normative account of when a response succeeds in qualifying as an appreciation of art qua art.

Measurement Theory in Language Testing: Past Traditions and Current Trends

ERIC Educational Resources Information Center

Salmani-Nodoushan, Mohammad Ali

2009-01-01

A good test is one that has at least three qualities: reliability, or the precision with which a test measures what it is supposed to measure; validity, i.e., if the test really measures what it is supposed to measure; and practicality, or if the test, no matter how sound theoretically, is practicable in reality. These are the sine qua non for…

Sine Qua Non: Expanding the Operational Art Form to Incorporate Interagency Function

DTIC Science & Technology

2010-05-21

the pages of this monograph with their leadership, perspectives, advice, and service to the nation. Among them: Christian Barratt , Dr. Tom W...2010; Christian Barratt (USAID representative to EPRT5) email to author, February 21, 2010. 38 incoming unit, 2/25 SBCT and the other members of...116 Operational Leadership Experiences Project: Interview with Major John Dale Highfill, January 27, 2010; Christian Barratt (USAID

Sine Qua Non: Indispensable Resources for Ed Tech Professionals. Part 2: Leadership

ERIC Educational Resources Information Center

Conley, Kate

2004-01-01

Integrating technology into curricula requires more than just placing the latest and greatest hardware and software in a classroom. Effective integration requires leadership. In Part 2 of this series on essential resources, the focus is on resources related to leadership. As with Part 1 ("L&L," March 2004, pp. 10-13), these resources were compiled…

All optical experimental design for neuron excitation, inhibition, and action potential detection

NASA Astrophysics Data System (ADS)

Walsh, Alex J.; Tolstykh, Gleb; Martens, Stacey; Sedelnikova, Anna; Ibey, Bennett L.; Beier, Hope T.

2016-03-01

Recently, infrared light has been shown to both stimulate and inhibit excitatory cells. However, studies of infrared light for excitatory cell inhibition have been constrained by the use of invasive and cumbersome electrodes for cell excitation and action potential recording. Here, we present an all optical experimental design for neuronal excitation, inhibition, and action potential detection. Primary rat neurons were transfected with plasmids containing the light sensitive ion channel CheRiff. CheRiff has a peak excitation around 450 nm, allowing excitation of transfected neurons with pulsed blue light. Additionally, primary neurons were transfected with QuasAr2, a fast and sensitive fluorescent voltage indicator. QuasAr2 is excited with yellow or red light and therefore does not spectrally overlap CheRiff, enabling imaging and action potential activation, simultaneously. Using an optic fiber, neurons were exposed to blue light sequentially to generate controlled action potentials. A second optic fiber delivered a single pulse of 1869nm light to the neuron causing inhibition of the evoked action potentials (by the blue light). When used in concert, these optical techniques enable electrode free neuron excitation, inhibition, and action potential recording, allowing research into neuronal behaviors with high spatial fidelity.

STS-72 crew trains in Fixed Base (FB) Shuttle Mission Simulator (SMS)

NASA Image and Video Library

1995-06-07

S95-12725 (May 1995) --- Astronaut Koichi Wakata, representing Japan's National Space Development Agency (NASDA) and assigned as mission specialist for the STS-72 mission, checks over a copy of the flight plan. Wakata is on the flight deck of the fixed base Shuttle Mission Simulator (SMS) at the Johnson Space Center (JSC). In the background is astronaut Brent W. Jett, pilot. The two will join four NASA astronauts aboard Space Shuttle Endeavour for a scheduled nine-day mission, now set for the winter of this year.

KSC-06pd1745

NASA Image and Video Library

2006-08-07

KENNEDY SPACE CENTER, FLA. - STS-115 Commander Brent Jett introduces his crew to waiting media at KSC's Shuttle Landing Facility after their arrival from Houston. The STS-115 crew has flown to NASA's Kennedy Space Center to take part in Terminal Countdown Demonstration Test activities. The TCDT is a pre-launch preparation that includes practicing emergency egress from the pad, driving an M-113 armored personnel carrier, and simulating the launch countdown. Launch of STS-115 is currently scheduled for Aug. 27. Photo credit: NASA/George Shelton

Brant (Branta bernnicla)

USGS Publications Warehouse

Ward, David H.; Derksen, Dirk V.; Reed, A.; Sedinger, J.S.

2013-01-01

The Brant (called Brent Goose in Europe) is a small dark goose that occurs throughout much of the northern hemisphere. In contrast to other goose species, Brant are characterized by their extensive use of native coastal habitats outside the breeding season. Three to four subspecies are recognized (see Systematics), mainly on the basis of plumage characteristics. The two/three North American subspecies are further separated into four subpopulations based on genetics, location of breeding and wintering areas, and migration routes.

Honey Creek Watershed Project. Tillage Documentation Results - 1980.

DTIC Science & Technology

1981-01-01

planting to harvest, economic data and soil erosion information are reported. This publication Is a compilation of data and information gathered...farm operation rather than less. Reduced tillage and no-till farming especially can improve water qua- lity by reducing soil loss through erosion...control. Soil retained in your fields means that expensive fertilizers, particularly phosphorus, and herbi- cides stay in place, too. Time and fuel savings

The Effects of Two Study Methods on Memory

DTIC Science & Technology

1987-07-01

hypothesis that optimal processing of individual words, qua individual words is sufficient to support good recall" (Craik & Tulving , 1975, p. 27...Likewise, mnemonic strategies, such as creating a story (Bel- lezza, Cheesman, & Reddy, 19/7) or categories (Mandler, Pearlstone , & Koopmans, 1969) for...that optimal retrieval per- formance is produced by extensive semantic processing for the individual item (Craik & Tulving , 1975; Hyde & Jenkins, 1973

USSR Report, Political and Sociological Affairs, Peoples of Asia and Africa, No. 2, Mar - Apr 1985.

DTIC Science & Technology

1985-08-30

U.S. Government, PROCUREMENT OF PUBLICATIONS JPRS publications may be ordered from the National Technical Information Service (NTIS), Springfield...matters other than procurement may be addressed to Joint Publications Research Service, 1000 North Glebe Road, Arlington, Virginia 22201. Soviet...sine qua non of the successful solution of their problems. PERSIAN GULF IN POLICIES OF IMPERIALIST POWERS V.V. Mashin, A.I. Yakovlev The article

AgBufferBuilder: A geographic information system (GIS) tool for precision design and performance assessment of filter strips

Treesearch

M. G. Dosskey; S. Neelakantan; T. G. Mueller; T. Kellerman; M. J. Helmers; E. Rienzi

2015-01-01

Spatially nonuniform runoif reduces the water qua1iry perfortnance of constant- width filter strips. A geographic inlormation system (Gls)-based tool was developed and tested that ernploys terrain analysis to account lor spatially nonuniform runoffand produce more ellbctive filter strip designs.The computer program,AgBufTerBuilder, runs with ATcGIS versions 10.0 and 10...

Social Capital and Stability Operations

DTIC Science & Technology

2008-03-26

defined as an instantiated set of informal values or norms that permit cooperation between two or more individuals, is the sine qua non of stable... multi -dimensional research, and editorial opinions, relate to the means (resources) by which to accomplish stability operations: unified action...development phase requires weaning indigenous institutions from reliance on external assistance. Fukuyama asserts that this is hard for three reasons

The Long March. Building an Afghan National Army

DTIC Science & Technology

2009-01-01

UNDP, 2007). Illiteracy and gender discrimination remain widespread. Additionally, 2006 witnessed a significant rise in terror- ist attacks and a 59...TERRORISM AND HOMELAND SECURITY TRANSPORTATION AND INFRASTRUCTURE WORKFORCE AND WORKPLACE The RAND Corporation is a nonprofit research organization...ANA) is seen as a sine qua non for security in Afghanistan. The recent resurgence of the Taliban, operating out of bases in Pakistan and parts of

Identifying the multiscale impacts of crude oil price shocks on the stock market in China at the sector level

NASA Astrophysics Data System (ADS)

Huang, Shupei; An, Haizhong; Gao, Xiangyun; Huang, Xuan

2015-09-01

The aim of this research is to investigate the multiscale dynamic linkages between crude oil price and the stock market in China at the sector level. First, the Haar à trous wavelet transform is implemented to extract multiscale information from the original time series. Furthermore, we incorporate the vector autoregression model to estimate the dynamic relationship pairing the Brent oil price and each sector stock index at each scale. There is a strong evidence showing that there are bidirectional Granger causality relationships between most of the sector stock indices and the crude oil price in the short, medium and long terms, except for those in the health, utility and consumption sectors. In fact, the impacts of the crude oil price shocks vary for different sectors over different time horizons. More precisely, the energy, information, material and telecommunication sector stock indices respond to crude oil price shocks negatively in the short run and positively in the medium and long runs, terms whereas the finance sector responds positively over all three time horizons. Moreover, the Brent oil price shocks have a stronger influence on the stock indices of sectors other than the health, optional and utility sectors in the medium and long terms than in the short term. The results obtained suggest implication of this paper as that the investment and policymaking decisions made during different time horizons should be based on the information gathered from each corresponding time scale.

Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place, FY 85. Part 14 (Middletown Limousine Sus - North American Carbide Tooling).

DTIC Science & Technology

1985-01-01

Suite � .4 u ~~c s~~e IBo OFFICE SYP.40O 9 PROCUREMENT INSTRUMENT IDENTIFICATION NUMBER O(AN.’-i U0 j if aPPIicabJC) h,~ .. . (City State and ZIP...4 -4 4 4 A 9 o4 m1W "i 0 M () A W I0100 (n .n00 . . . . . . -.j 0 4 44 44 03 :O 󈧇 0-. (N UN001 WL 4 0 -44 4cm ito o-NN1100II0erP-s-40 -4 WC.1- 1󈧄...00 ( 0 I . ) ) 0-6(CO001 2Z00 000 00 c oG c ) 0 00 *00 Ga* c c 00000 to 0 so 0.aa.s4ha 90Omcc01caCO m((0 -101 - 009L - 009- 9 - LA- I 00 -0 00 444 00 44

Army Logistician. Volume 38, Issue 1, January-February 2006

DTIC Science & Technology

2006-02-01

BRENT D. CORYELL Legend: ABN = Airborne ACR = Armored Cavalry Regiment AD = Armor Division BCT = Brigade Combat Team CAV = Cavalry Division ID = Infantry...Division MTN = Mountain Division USAREUR = U.S. Army Europe 3d ID 2,039 pieces Complete 101st ABN 1,170 pieces Complete 1st AD , 3d BCT 326 pieces...Corps 138 pieces Complete 1st AD 155 pieces Complete 1st ID, 1st BCT 247 pieces Complete 25th ID 273 pieces 71% 1st CAV 760 pieces 66% 1st ID USAREUR

Mir 22 and STS-81 crew work with gyrodyne

NASA Image and Video Library

1997-02-04

STS081-301-032 (12-22 Jan. 1997) --- Shortly after the docking of the Space Shuttle Atlantis and Russia's Mir Space Station, crewmembers from the respective spacecraft begin to transfer hardware from the Spacehab Double Module (DM) onto the Mir complex. In this scene, cosmonaut Valeri G. Korzun (second left) Mir-22 commander, along with astronauts Michael A. Baker (second right) commander, and Brent W. Jett, Jr., pilot, unstow a gyrodyne, a device used for attitude control, for transfer to Mir. Astronaut Marsha S. Ivins looks over a lengthy inventory of supplies to be transferred.

KSC-00padig108

NASA Image and Video Library

2000-11-28

During pre-pack and fit check in the Operations and Checkout Building, STS-97 Commander Brent Jett gets help with his gloves from suit technician Bill Todd. Mission STS-97 is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:06 p.m. EST

STS-97 Mission Specialist Garneau with full launch and entry suit during pre-pack and fit check

NASA Technical Reports Server (NTRS)

2000-01-01

During pre-pack and fit check in the Operations and Checkout Building, STS-97 Commander Brent Jett gets help with his gloves from suit technician Bill Todd. Mission STS-97 is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:06 p.m. EST.

Bob was right.

PubMed

Holmes, L B

1997-01-01

During his career Bob Brent has been instrumental in developing the methodology to use in determining whether an exposure in pregnancy has a harmful effect on the fetus. Experience has also shown the importance of using this approach to determine when an exposure is not teratogenic. Unfortunately, the attendant debate, as illustrated in two examples reviewed, exogenous sex hormones and Bendectin, requires persistence and a thick skin. Bob has recorded in several publications how he carried out these systematic analyses. This literature will be a very valuable legacy.

STS-115 Crew Portrait

NASA Technical Reports Server (NTRS)

2002-01-01

These six astronauts take a break from training to pose for the STS-115 crew portrait. Astronauts Brent W. Jett, Jr. (right) and Christopher J. Ferguson, commander and pilot, respectively, flank the mission insignia. The mission specialists are, from left to right, astronauts Heidemarie M. Stefanyshyn-Piper, Joseph R. (Joe) Tanner, Daniel C. Burbank, and Steven G. MacLean, who represents the Canadian Space Agency. This mission continued the assembly of the International Space Station (ISS) with the installation of the truss segments P3 and P4.

Expedition One and STS-97 crew pose for portrait

NASA Image and Video Library

2000-12-08

S97-E-5144 (8 December 2000) --- The STS-97 astronauts and the Expedition 1 crew members pose for an historic portrait onboard the International Space Station (ISS) shortly after hatches were opened between the Space Shuttle Endeavour and the station. In front, from the left, are Sergei K. Krikalev, Brent W. Jett, Jr., William M. Shepherd and Joseph R. Tanner. In back, from the left, are Marc Garneau, Carlos I. Noriega, Yuri P. Gidzenko and Michael J. Bloomfield. A pre-set digital still camera was used to record the scene.

Effect of Mixed Culture Growth Conditions on the Cellular Fatty Acids of Streptococci (Analyzed by High Performance Liquid Chromatography),

DTIC Science & Technology

1980-10-16

mixed culture with Streptococcus S mutans , Streptococcus singuis Staphylococcus aureus,*and Escheric ia coi 1 - sA -DoWed n o quaI It atfI ve -c nah...of both S. mutans and S. scnguis. I 4 |I KEY WORDS: Fatty Acids . High Performance Liquid Chromatography Mixed Bacterial Cultures Streptococcus sal...AND METHODS Streptococcus mutans (ATCC 25175), Streptococcus sanguis (ATCC 10557), Staphylococcus aureus (ATCC 25923) and Escherichia coli (ATCC 25922

Oceanography of the Grand Banks Region of Newfoundland, March 1974-October 1974.

DTIC Science & Technology

1978-07-01

or Hayes (1978). Newfoundland. Station 11649 was deleted . The Deep-sea reversing thermometer and salinity most dominant feature of this survey was...02 O.tA lOS1 1 51118 1. SEA W140401 UM 1(2*7* 00.41 2 10(261 24 LONG 046 54.0k HO" 13.4 AafiA 05 CL.M TIA CLITA 5(EATPHAR .. WIG 0il 651 A $QUA* $6

Latin America in the 1990’s: Implications for US Security,

DTIC Science & Technology

1981-01-01

world.. These amounts will increase significantly in the next decade. US political interests stress cooperative relations with the multi - plicity of...Americans and Puerto Ricans to contemplate, but the independence option is entirely within US law; more- over, economic viability is not a sine qua non...prescription is nothing new--normalization of relations in order to be- gin the long and difficult process of weaning the Cubans from the Soviets. This

Decision-Making Uncertainty and the Use of Force in Cyberspace: A Phenomenological Study of Military Officers

DTIC Science & Technology

2010-10-01

theory becomes a more comprehensive and persuasive model for describing and predicting behavioral decision-making factors ( Bell , 1982). Böhm and...inductively analyzing the rich data collected in their natural setting ( Bryman , 1984; Leedy & Ormrod, 2010; Neuman, 2005). A phenomenological...qualitative methods, the “sine qua non is a commitment to see the world from the point of view of the actor” ( Bryman , 1984, p. 77). Therefore, the

Academic Civic Mindedness and Model Citizenship in the International Baccalaureate Diploma Programme. Working Paper WR-1044-IBO

ERIC Educational Resources Information Center

Saavedra, Anna Rosefsky

2014-01-01

Originally founded as a private means for diplomats' children to earn an internationally recognized high school diploma, today the International Baccalaureate (IB) Diploma Programme (DP) serves students from a variety of backgrounds in 144 countries. The IB mission and Learner Profile--consisting of ten attributes to foster in students--suggest…

Quantitative traits and diversification.

PubMed

FitzJohn, Richard G

2010-12-01

Quantitative traits have long been hypothesized to affect speciation and extinction rates. For example, smaller body size or increased specialization may be associated with increased rates of diversification. Here, I present a phylogenetic likelihood-based method (quantitative state speciation and extinction [QuaSSE]) that can be used to test such hypotheses using extant character distributions. This approach assumes that diversification follows a birth-death process where speciation and extinction rates may vary with one or more traits that evolve under a diffusion model. Speciation and extinction rates may be arbitrary functions of the character state, allowing much flexibility in testing models of trait-dependent diversification. I test the approach using simulated phylogenies and show that a known relationship between speciation and a quantitative character could be recovered in up to 80% of the cases on large trees (500 species). Consistent with other approaches, detecting shifts in diversification due to differences in extinction rates was harder than when due to differences in speciation rates. Finally, I demonstrate the application of QuaSSE to investigate the correlation between body size and diversification in primates, concluding that clade-specific differences in diversification may be more important than size-dependent diversification in shaping the patterns of diversity within this group.

An internal morality of nursing: what it can and cannot do.

PubMed

Newham, Roger A

2013-04-01

It has been claimed that there are certain acts that nurses as people practising nursing (nurses qua nurses) must never do because they are nurses and this is regardless of what the same agent (when not acting in the role of a nurse) should do; that certain actions are not part of proper nursing practice. The concept of an internal morality has been discussed in relation to medicine and has been used to ground the actions proper to medicine in a realist tradition. Although the concept of an internal morality of nursing is not explicitly mentioned in the literature the underpinning ideas about the proper practice of nursing based on philosophical realism I argue equate with it and a discussion of the method of an internal morality can help to understand how arguments against euthanasia (amongst other acts) related to the profession of nursing are far from clear. Ultimately, although the idea of particular acts proper to nurses qua nurses is not clear, the concept of an internal morality can help to get practitioners to see how the profession is tightly linked to moral actions, even so the hard problems in bioethics such as the morality of euthanasia remain hard for all and the easy ones easy for all. © 2013 Blackwell Publishing Ltd.

Sine Qua Non: Indispensable Resources for Ed Tech Professionals. Part 1: Educational Technology

ERIC Educational Resources Information Center

Conley, Kate

2004-01-01

Because the field of educational technology is so broad and dynamic, it is extremely difficult to find time to keep up with the best practices, current research, and innovative ideas. In an effort to help readers keep up their knowledge of the field and to determine some of the most interesting and useful resources to date, a large body of…

Clinical simulation: a sine qua non of nurse education or a white elephant?

PubMed

Stayt, Louise C

2012-07-01

An emphasis has been placed on clinical skill development in nurse education curricula due to the expressed concern about nursing students' clinical competence at the point of registration. Hence, the use of clinical simulation as an educational tool has become increasingly popular. The aim of this article is to examine the learning theory that underpins clinical simulation by utilising Carper's patterns of knowing (1978) as a theoretical framework. It is revealed that there is a philosophical conflict between the different learning approaches required to meet all the expected learning outcomes. It would also appear that due to a paucity of the current evidence base that the cost benefits of clinical simulation are largely unknown. The implications of these limitations may in part be overcome by future research endeavours, judicious curriculum development and a pluralistic approach to the facilitation of clinical simulation. Copyright © 2011 Elsevier Ltd. All rights reserved.

Science and Technology in the Soviet Union: Proceedings of a Conference Held at Stanford, California on 26-27 July 1984.

DTIC Science & Technology

1985-01-31

other disciplines, whether political, economic or social, acknowledge this same failure to keep abreast of international developments in these fields. No...the significance of scientific developments abroad in a more accurate and timely way is the sine qua non, if we are to respond rationally to the diverse...examples of important scientific developments to wl[ich we in the US have been hardly privy abound. Few in this room require ampli- fication of this remark

Identification of TNT Transformation Products in Soil

DTIC Science & Technology

1992-06-01

Unannounced 0 Just i•icatio BYDlstrtbton, --.- Availabilit ? CodoeS Dist Special moI QUA=~lI3E1 3 ii CONTENTS Preface...extracted. Soil-to-solvent ratios varied from 1:2 to (Jenkins et al. 1989) and water (Jenkins et al. 1986, 1:5 (mass [g]:volume [mL]); the smallest...cultures, composting systems and MassSelectiveDetector (MSD) throughaHewlett- water , little research has been conducted to define Packard 5890 Series

Risk Assessment Report, Davis Global Communications Site

DTIC Science & Technology

1994-02-23

trivalent chromium . Hexavalent chromium typically is unstable in soil and readily mobilized in both acid and alkaline soils (Bartlett and James, 1979...Environ. Qual. 8: 31. 1 Bartlett, R. J., and J. M. Kimble. 1976a. "Behavior of chromium in soils. I. Trivalent forms." J Environ. QuaL 5: 379-382. 3 i...Background data were not available from these sources for antimony, cadmium, hexavalent chromium , thallium, and silver. Other literature sources, discussed

What is Aspect-Oriented Programming, Revisited

NASA Technical Reports Server (NTRS)

Filman, Robert E.; Norvig, Peter (Technical Monitor)

2001-01-01

For the Advanced Separation of Concerns workshop at OOPSLA 2000 in Minneapolis, Dan Friedman and I wrote a paper that argued that the distinguishing characteristic of Aspect-Oriented Programming systems (qua programming systems) is that they provide quantification and obliviousness. In this paper, I expand on the themes of our Minneapolis workshop paper, respond to some of the comments we've received on that paper, and provide a computational formalization of the notion of quantification.

Sexually transmitted infection risk exposure among black and minority ethnic youth in northwest London: findings from a study translating a sexually transmitted infection risk-reduction intervention to the UK setting.

PubMed

Gerressu, M; Elam, G; Shain, R; Bonell, C; Brook, G; Champion, J Dimmitt; French, R; Elford, J; Hart, G; Stephenson, J; Imrie, J

2009-08-01

Young black women are disproportionately affected by sexually transmitted infections (STI) in the UK, but effective interventions to address this are lacking. The Young Brent Project explored the nature and context of sexual risk-taking in young people to inform the translation of an effective clinic-based STI reduction intervention (Project SAFE) from the USA to the UK. One-to-one in-depth interviews (n = 37) and group discussions (n = 10) were conducted among men and women aged 15-27 years from different ethnic backgrounds recruited from youth and genitourinary medicine clinic settings in Brent, London. The interviews explored the context within which STI-related risks were assessed, experienced and avoided, the skills needed to recognise risk and the barriers to behaviour change. Concurrent sexual partnerships, mismatched perceptions and expectations, and barriers to condom use contributed to STI risk exposure and difficulties in implementing risk-reduction strategies. Women attempted to achieve monogamy, but experienced complex and fluid sexual relationships. Low risk awareness, flawed partner risk assessments, negative perceptions of condoms and lack of control hindered condom use. Whereas men made conscious decisions, women experienced persuasion, deceit and difficulty in requesting condom use, particularly with older partners. Knowledge of STI and condom use skills is not enough to equip young people with the means to reduce STI risk. Interventions with young women need to place greater emphasis on: entering and maintaining healthy relationships; awareness of risks attached to different forms of concurrency and how concurrency arises; skills to redress power imbalances and building self-esteem.

An efficient algorithm for the retarded time equation for noise from rotating sources

NASA Astrophysics Data System (ADS)

Loiodice, S.; Drikakis, D.; Kokkalis, A.

2018-01-01

This study concerns modelling of noise emanating from rotating sources such as helicopter rotors. We present an accurate and efficient algorithm for the solution of the retarded time equation, which can be used both in subsonic and supersonic flow regimes. A novel approach for the search of the roots of the retarded time function was developed based on considerations of the kinematics of rotating sources and of the bifurcation analysis of the retarded time function. It is shown that the proposed algorithm is faster than the classical Newton and Brent methods, especially in the presence of sources rotating supersonically.

ARC-1969-A-36324

NASA Image and Video Library

1966-02-01

MANNED SPACECRAFT SIMULATION BRANCH PERSONNEL - Top row, L-R: Henry C. Lessing, Dallas G. Denery, Richard Acken, Robert E. Coate. Secon row, L-R: Frederick W. Boltz, Kenneth C. White, Gordon H. Hardy, Donald W. Smith. Third row, L-R: Rodney C. Wingrove, Bedford A. Lampkin, Armando E. Lopez, DeLamar W. Watson. Bottom row, L-R: Richard L. Kurkowski, Michele H. Hilliard, Brent Y. Creer, Grace M. Webster, Frederick G. Edwards. Note: Used in publication in Flight Research at Ames; 57 Years of Development and Validation of Aeronautical Technology NASA SP-1998-3300 fig 90

KSC00pp1420

NASA Image and Video Library

2000-09-16

In Orbiter Processing Facility bay 2 during a Crew Equipment Interface Test (CEIT), STS-97 Pilot Michael Bloomfied (left) and Commander Brent Jett (right) check out the cockpit of orbiter Endeavour as part of preflight preparations. The CEIT provides an opportunity for crew members to check equipment and facilities that will be on board the orbiter during their mission. The STS-97 mission will be the sixth construction flight to the International Space Station. The payload includes a photovoltaic (PV) module, providing solar power to the Station. STS-97 is scheduled to launch Nov. 30 from KSC for the 10-day mission

KSC-00pp1420

NASA Image and Video Library

2000-09-16

In Orbiter Processing Facility bay 2 during a Crew Equipment Interface Test (CEIT), STS-97 Pilot Michael Bloomfied (left) and Commander Brent Jett (right) check out the cockpit of orbiter Endeavour as part of preflight preparations. The CEIT provides an opportunity for crew members to check equipment and facilities that will be on board the orbiter during their mission. The STS-97 mission will be the sixth construction flight to the International Space Station. The payload includes a photovoltaic (PV) module, providing solar power to the Station. STS-97 is scheduled to launch Nov. 30 from KSC for the 10-day mission

KSC00pp1421

NASA Image and Video Library

2000-09-16

In Orbiter Processing Facility bay 2 during a Crew Equipment Interface Test (CEIT), STS-97 Commander Brent Jett (left) and Pilot Michael Bloomfied (right) check out the cockpit of orbiter Endeavour as part of preflight preparations. The CEIT provides an opportunity for crew members to check equipment and facilities that will be on board the orbiter during their mission. The STS-97 mission will be the sixth construction flight to the International Space Station. The payload includes a photovoltaic (PV) module, providing solar power to the Station. STS-97 is scheduled to launch Nov. 30 from KSC for the 10-day mission

KSC00pp1422

NASA Image and Video Library

2000-09-16

During a Crew Equipment Interface Test (CEIT), STS-97 Commander Brent Jett (left) and Pilot Michael Bloomfied (right) check out the cockpit of orbiter Endeavour in Orbiter Processing Facility bay 2 as part of preflight preparations. The CEIT provides an opportunity for crew members to check equipment and facilities that will be on board the orbiter during their mission. The STS-97 mission will be the sixth construction flight to the International Space Station. The payload includes a photovoltaic (PV) module, providing solar power to the Station. STS-97 is scheduled to launch Nov. 30 from KSC for the 10-day mission

KSC-00pp1422

NASA Image and Video Library

2000-09-16

During a Crew Equipment Interface Test (CEIT), STS-97 Commander Brent Jett (left) and Pilot Michael Bloomfied (right) check out the cockpit of orbiter Endeavour in Orbiter Processing Facility bay 2 as part of preflight preparations. The CEIT provides an opportunity for crew members to check equipment and facilities that will be on board the orbiter during their mission. The STS-97 mission will be the sixth construction flight to the International Space Station. The payload includes a photovoltaic (PV) module, providing solar power to the Station. STS-97 is scheduled to launch Nov. 30 from KSC for the 10-day mission

KSC-00pp1421

NASA Image and Video Library

2000-09-16

In Orbiter Processing Facility bay 2 during a Crew Equipment Interface Test (CEIT), STS-97 Commander Brent Jett (left) and Pilot Michael Bloomfied (right) check out the cockpit of orbiter Endeavour as part of preflight preparations. The CEIT provides an opportunity for crew members to check equipment and facilities that will be on board the orbiter during their mission. The STS-97 mission will be the sixth construction flight to the International Space Station. The payload includes a photovoltaic (PV) module, providing solar power to the Station. STS-97 is scheduled to launch Nov. 30 from KSC for the 10-day mission

KSC-2013-3561

NASA Image and Video Library

2013-08-15

DRYDEN FLIGHT RESEARCH CENTER, Calif. - Simulation technicians Brent Bieber, left, and Dennis Pitts install a boilerplate Dream Chaser canopy structure over the cockpit of a flight simulator in the simulation laboratory at NASA's Dryden Flight Research Center in California. The modification will give Dream Chaser pilot-astronauts a more representative view of the actual flight profiles the spacecraft would fly during piloted approach and landing tests. Sierra Nevada Corporation's Space Systems division is conducting uncrewed captive- and free-flight approach and landing tests of its Dream Chaser at Dryden during the summer and fall. Photo credit: NASA/Ken Ulbrich

STS-115 crew visits SSC

NASA Technical Reports Server (NTRS)

2006-01-01

Commander Brent Jett (center) talks with employees and visitors at NASA Stennis Space Center. The astronauts of NASA's STS-115 space shuttle mission visited SSC in south Mississippi to share highlights of their 12-day mission and to thank SSC employees for the reliability of the space shuttle's main engines, which helped propel Space Shuttle Atlantis into orbit. STS-115's other crewmembers are (from left) Mission Specialists Joe Tanner, Dan Burbank, Heidemarie Stefanyshyn-Piper and Steve MacLean of the Canadian Space Agency. The mission launched Sept. 9, 2006, resuming construction of the International Space Station.

STS-72 Flight Day 7

NASA Technical Reports Server (NTRS)

1996-01-01

On this seventh day of the STS-72 mission, the flight crew, Cmdr. Brian Duffy, Pilot Brent W. Jett, and Mission Specialists Leroy Chiao, Daniel T. Barry, Winston E. Scott, and Koichi Wakata (NASDA), awakened to music from the Walt Disney movie, 'Snow White and the Seven Dwarfs.' Chiao and Scott performed the second spacewalk of the mission where they tested equipment and work platforms that will be used in building the planned International Space Station. This spacewalk was almost seven hours long. Wakata conducted an interview with and answered questions from six graders from a Japanese school in Houston, Texas.

STS-72 Flight Day 5

NASA Technical Reports Server (NTRS)

1996-01-01

On this fifth day of the STS-72 mission, the flight crew, Cmdr. Brian Duffy, Pilot Brent W. Jett, and Mission Specialists Leroy Chiao, Daniel T. Barry, Winston E. Scott, and Koichi Wakata (NASDA), awakened to music from the television show, 'Star Trek: The Next Generation'. Chiao and Barry are shown suiting up for the first of the two scheduled 6 1/2 hour spacewalks and, later, conducting tests with various tools and materials from the shuttle's cargo bay during the spacewalk. The new heating and cooling units in the spacesuits will be tested during these EVAs.

Hatch opening and greeting after rendezvous

NASA Image and Video Library

1997-02-27

STS081-373-025 (14 Jan 1997) --- Greeting between commanders - astronaut Michael A. Baker (foreground) and cosmonaut Valeri G. Korzun - just after hatch opening following the January 14, 1997, docking. Out of frame on the Space Shuttle Atlantis is astronaut Jerry M. Linenger, soon to be trading places with John E. Blaha, the current cosmonaut guest researcher, onboard Russia?s Mir Space Station since mid September 1996. Along with Baker and Linenger, other crew members now aboard Atlantis are astronauts Brent W. Jett, Jr., pilot; and mission specialists John M. Grunsfeld, Marsha S. Ivins and Peter J. K. (Jeff) Wisoff.

Fake Statistically Valid Isotopic Ages in Impact Crater Geochronology

NASA Astrophysics Data System (ADS)

Jourdan, F.; Schmieder, M.; McWilliams, M. M.; Buchner, E.

2009-05-01

Precise dating of impact structures is crucial in several fundamental aspects, such as correlating effects on the bio- and geosphere caused by these catastrophic processes. Among the 176 listed impact structures [1], only 25 have a stated age precision better than ± 2%. Statistical investigation of these 25 ages showed that 11 ages are accurate, 12 are at best ambiguous, and 2 are not well characterized [2]. In this study, we show that even with statistically valid isotope ages, the age of an impact can be "missed" by several hundred millions of years. We present a new 40Ar/39Ar plateau age of 444 ± 4 Ma for the Acraman structure (real age ˜590 Ma [3]) and four plateau ages ranging from 81.07 ± 0.76 Ma to 74.6 ± 1.5 Ma for the Brent structure (estimated real age ˜453 Ma [4]). In addition, we discuss a 40Ar/39Ar plateau age of 994 ± 11, recently obtained by [5] on the Dhala structure (real age ˜2.0 Ga [5]). Despite careful sample preparations (single grain handpicking and HF leaching, in order to remove alteration phases), these results are much younger than the impact ages. Petrographic observations show that Acraman and Dhala grain separates all have an orange color and show evidence of alteration. This suggests that these ages are the results of hydrothermal events that triggered intensive 40Ar* loss and crystallization of secondary phases. More intriguing are the Brent samples (glassy melt rocks obtained from a drill core) that appeared very fresh under the microscope. The Brent glass might be a Cretaceous pseudotachylite generated by a late adjustment of the structure and/or by a local earthquake. Because we know the approximate age of the craters with stratigraphic evidences, these outliers are easy to identify. However, this is a red flag for any uncritical interpretation of isotopic ages (including e.g., 40Ar/39Ar, U/Pb, or U-Th/He [6]). In this paper, we encourage a multi-technique approach (i.e., isotopic, stratigraphic, paleogeographic [7,8]) and

Kinetics and Mechanism of Chemical Marker Formation and Water-Activated Heat Generation

DTIC Science & Technology

1994-05-01

activated chemical heaters. It has recently been discovered at the Army’s Natick, Massachusetts Research, Development & Engineering Center that certain...FUNDING NUMBERS 0 i Kinetics and Mechanism of Chemical Marker Formation and Water-Activated Heat Generation ~~ 3 6. AUTHOR(S) I-GZ05 Kenneth Kustin DI N...unlimited. rpIC Q.UA y uI sECTED 5 13. ABSTRACT (Maximum 200 words) n Research has been conducted on two projects: intrinsic chemical markers and water

Annual Report of the ECSU Home-Institution Support Program (1993)

DTIC Science & Technology

1993-09-30

summer of 1992. Stephanie plans to attend graduate school at the University of Alabama at Birmingham. r 3 . Deborah Jones has attended the ISSP program for...computer equipment Component #2 A visiting lecturer series Component # 3 : Students pay & faculty release time Component #4 Student/sponsor travel program...DTXC QUA, ty rNpBT 3 S. 0. CODE: 1133 DISBURSING CODE: N001 79 AGO CODE: N66005 CAGE CODE: OJLKO 3 PART I: A succinct narrative which should

[Issues of biomedical support of explorations missions].

PubMed

Potapov, A N; Sinyak, Yu E; Petrov, V M

2013-01-01

Sine qua non for piloted exploration missions is a system of biomedical support. The future system will be considerably different from the analogous systems applied in current orbital missions. The reason is the challenging conditions in expeditions to remote space. In a mission to Mars, specifically, these are high levels of radiation, hypomagnetic environment, alternation of micro- and hypogravity, very long mission duration and autonomy. The paper scrutinizes the major issues of medical support to future explorers of space.

Granma: Cuban News and Propaganda Analysis for the Period, 1-31 January 1985.

DTIC Science & Technology

1985-01-01

qua brarse, puesto que Satielan- firms del exterior, ambas refe- con el agua que norialmente no es rico, 4no ec.01MoI ridas a plantas de trataniento...goverment announced price increases in basic commodities. " During the war in the Falkland Islands, a secret agreement between Great Britian and Chile ...death and destruction of pro- perty. 0 Chile declined an invitation to attend the inauguration of the Presi- dent elect of Brazil. e Many people in

Reconstructing the Soviet National Economic Balance, 1965 - 1984: An Alternative Approach to Estimating Soviet Military Expenditures. Volume 1. Technical Discussion

DTIC Science & Technology

1986-03-11

official Department of Defense position,IA-1 policy, or decision, unless so designated by other official documentation*. DIIO QUA~L~ Lo 0ýi’WD T !C10...least appeared to contain numerous inconsistencies that might be deliberately designed to mislead I Western analysts. Becker’s original assessment of...Construction Works without Collectives 1965-1984 m NK53 Construction Works with Collectives 1965-1984 NK54 Construction Design Works 1965-1984 NK55 Geological

Cervical Chondrocutaneous Branchial Remnants.

PubMed

Ginat, Daniel T; Johnson, Daniel N; Shogan, Andrea; Cipriani, Nicole A

2018-06-01

Cervical chondrocutaneous branchial remnants are rare congenital choristomas. These lesions contain a cartilage core surrounded by skin with adnexal structures and subcutaneous fat. Correspondingly, on ultrasound there is a tubular hypoechoic core surrounded by hyperechoic, while on CT there is central intermediate attenuation surrounded by fat attenuation tissues. These features are exemplified in this sine qua non radiology-pathology correlation article. Management includes complete surgical resection and evaluating for potential associated anomalies, such as other branchial apparatus anomalies, as well as cardiac anomalies.

Proof of the Feasibility of Coherent and Incoherent Schemes for Pumping a Gamma-Ray Laser

DTIC Science & Technology

1988-10-01

TheUnierstyof Texas. at Dallas Center for’ "Quantum, Electronics The IGamm~a-7Ra~y.,La’ser. Project o Qua’rter’l y’ Report SJuly-September .1988 Co...Dallas Center for Quantum Electronics P.O. Box 830688 Richardson, Texas 75083-0688 October 1988 0 Quarterly Technical Progress Report 1 July 1988...ADDRESS 10. PROGRAM ELEMENT. PROJECT, TASKAREA & WORK UNIT NUM9ERS University of Texas at Dallas Center for Quantum Electronics P.O. Box 830688

Carboxyhemoglobin concentrations in flash fire victims: report of six simultaneous fire fatalities without elevated carboxyhemoglobin.

PubMed

Hirsch, C S; Bost, R O; Gerber, S R; Cowan, M E; Adelson, L; Sunshine, I

1977-09-01

Eight people died in a traffic accident involving a tractor-trailer and ten autos. The accident caused a series of flash fires from ruptured gas tanks. Complete autopsies established that six of the victims died exclusively from thermal trauma; none showed an elevated blood carboxyhemoglobin concentration. Flash fire victims are exceptions to the axiom that elevation of blood carboxyhemoglobin is a sine qua non for concluding that a decedent recovered from the scene of a conflagration was alive in the fire.

High Energy Density Capacitors for Pulsed Power Applications

DTIC Science & Technology

2009-07-01

As a result of this effort, the US Military has access to capacitors that are about a third the size and half the cost of the capacitors that were...resistor in terms of shock and vibration, mounting requirements, total volume, system reliability, and cost . All of these parameters were improved...it t tipo ymer m qua y an capac or cons ruc on. Energy Density of 10,000 Shot High Efficiency Pulse Power Capacitors The primary driver was 1 5

The intestinal microbiome and the leaky gut as therapeutic targets in alcoholic liver disease

PubMed Central

Hartmann, Phillipp; Chen, Wei-Chung; Schnabl, Bernd

2012-01-01

Alcoholic liver disease (ALD) encompasses hepatic steatosis, which may progress to alcoholic hepatitis, fibrosis, and cirrhosis. It remains a leading cause of morbidity and mortality in the US and worldwide. The severity of liver disease correlates with plasma levels of bacterial products in patients, and experimental ALD depends on the level of gut derived bacterial products in rodents. Since intestinal decontamination and deficiency of bacterial product receptors or their downstream signaling molecules protect from alcohol-induced liver disease, bacterial translocation (BT), qualitative, and quantitative changes of the enteric microbiome are considered as being of fundamental importance in the pathogenesis of ALD. Recent enhancements in diagnostic technologies provide a better insight into these shifts. This review highlights vital events in ALD such as BT, the importance of Toll-like receptor (TLR) signaling, intestinal bacterial overgrowth (IBO), and changes in the intestinal microbiome. Furthermore, a treatment trial section of patients reviews possible future options of therapy for ALD modifying the enteric microbiome. PMID:23087650

Accuracy optimization with wavelength tunability in overlay imaging technology

NASA Astrophysics Data System (ADS)

Lee, Honggoo; Kang, Yoonshik; Han, Sangjoon; Shim, Kyuchan; Hong, Minhyung; Kim, Seungyoung; Lee, Jieun; Lee, Dongyoung; Oh, Eungryong; Choi, Ahlin; Kim, Youngsik; Marciano, Tal; Klein, Dana; Hajaj, Eitan M.; Aharon, Sharon; Ben-Dov, Guy; Lilach, Saltoun; Serero, Dan; Golotsvan, Anna

2018-03-01

As semiconductor manufacturing technology progresses and the dimensions of integrated circuit elements shrink, overlay budget is accordingly being reduced. Overlay budget closely approaches the scale of measurement inaccuracies due to both optical imperfections of the measurement system and the interaction of light with geometrical asymmetries of the measured targets. Measurement inaccuracies can no longer be ignored due to their significant effect on the resulting device yield. In this paper we investigate a new approach for imaging based overlay (IBO) measurements by optimizing accuracy rather than contrast precision, including its effect over the total target performance, using wavelength tunable overlay imaging metrology. We present new accuracy metrics based on theoretical development and present their quality in identifying the measurement accuracy when compared to CD-SEM overlay measurements. The paper presents the theoretical considerations and simulation work, as well as measurement data, for which tunability combined with the new accuracy metrics is shown to improve accuracy performance.

Diffraction-based overlay measurement on dedicated mark using rigorous modeling method

NASA Astrophysics Data System (ADS)

Lu, Hailiang; Wang, Fan; Zhang, Qingyun; Chen, Yonghui; Zhou, Chang

2012-03-01

Diffraction Based Overlay (DBO) is widely evaluated by numerous authors, results show DBO can provide better performance than Imaging Based Overlay (IBO). However, DBO has its own problems. As well known, Modeling based DBO (mDBO) faces challenges of low measurement sensitivity and crosstalk between various structure parameters, which may result in poor accuracy and precision. Meanwhile, main obstacle encountered by empirical DBO (eDBO) is that a few pads must be employed to gain sufficient information on overlay-induced diffraction signature variations, which consumes more wafer space and costs more measuring time. Also, eDBO may suffer from mark profile asymmetry caused by processes. In this paper, we propose an alternative DBO technology that employs a dedicated overlay mark and takes a rigorous modeling approach. This technology needs only two or three pads for each direction, which is economic and time saving. While overlay measurement error induced by mark profile asymmetry being reduced, this technology is expected to be as accurate and precise as scatterometry technologies.

A dualist analysis of abortion: personhood and the concept of self qua experiential subject.

PubMed

Himma, K E

2005-01-01

There is no issue more central to the abortion debate than the controversial issue of whether the fetus is a moral person. Abortion-rights opponents almost universally claim that abortion is murder and should be legally prohibited because the fetus is a moral person at the moment of conception. Abortion-rights proponents almost universally deny the crucial assumption that the fetus is a person; on their view, whatever moral disvalue abortion involves does not rise to the level of murder and hence does not rise to the level of something that should be legally prohibited. In this essay, I argue that, under dualist assumptions about the nature of mind, the fetus is not a person until brain activity has begun.(i) First, I argue it is a necessary condition for a thing to be a moral person that it is (or has) a self. Second, I argue it is a necessary condition for a fetus to be (or have) a self, under dualist assumptions, that there has been some electrical activity in the brain. I conclude that a dualist can take the position that abortion ought to be legally permitted at least until the beginning of brain activity in the fetus.iI make no attempt to determine what conditions are sufficient for moral personhood; for this reason, the relevant claim about personhood is purely negative.

KSC-00padig099

NASA Image and Video Library

2000-11-27

After their arrival at the Shuttle Landing Facility, the STS-97 crew gather to address the media. At the microphone is Pilot Michael Bloomfield. Behind him stand Commander Brent Jett and Mission Specialists Joseph Tanner, Carolos Noriega and Marc Garneau, who is with the Canadian Space Agency. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:06 p.m. EST

ARC-1969-A-25541

NASA Image and Video Library

1959-08-04

FLIGHT RESEARCH BRANCH PERSONNEL-1959. FRONT ROW: George Rathert, Stu Brown, Norm McFadden, Howard Turner, Gus Brunner, Venia McCloud, Violet Shaw, Kay Rizzi, Yvonne Settle, Genevieve Ziegler, Anita Palmer, Grace Carpenter, Evelyn Olson. SECOND ROW: Bill Triplett, Alan Faye, Dick Bray, Seth Anderson, Steve Belsley, Hervey Quigley, Hank Cole, Elwood Stewart, Don Higdon, Maurie White, Dorothea Wilkinson, Dick Vomaske, Stew Rolls, Mel Sadoff, Mary Thompson, Brent Creer. BACK ROW: Ron Gerdes, Joe Douvillier, John Stewart, Rod Wingrove, Walter McNeill. Note: Used in publication in Flight Research at Ames; 57 Years of Development and Validation of Aeronautical Technology NASA SP-1998-3300 fig 89

STS-97 Crew Activity Report/Flight Day 11 Highlights

NASA Technical Reports Server (NTRS)

2000-01-01

On this eleventh day of the STS-97 mission, Commander Brent W. Jett, Pilot Michael J. Bloomfield, and Mission Specialists Joseph R. Tanner, Carlos I. Noriega, and Marc Garneau remain docked with the International Space Station (ISS) on board the Endeavour Orbiter. Jett and Bloomfield are seen performing a check of the shuttle flight controls in preparation for tomorrow's landing. Jett, Noriega, and Tanner answer questions about the mission and the goals fulfilled. Footage shows the Earth at night as the camera on Endeavour sweeps the Mediterranean coastline, outlined by city lights, showing Spanish/French border, the French Riviera, the Alps, Italy, Switzerland, and the German/Austrian border.

Views of the ISS during Endeavour's final flyaround for STS-97

NASA Image and Video Library

2000-12-09

STS097-703-030 (30 Nov.-11 Dec. 2000) --- The International Space Station (ISS) is photographed during a fly-around by the Space Shuttle Endeavour. The 240-foot-long, 38-foot-wide solar array (top) is the newest part and one of the most prominent components of the station. Onboard ISS for about 40 days at the time of this photo were astronaut William M. Shepherd and cosmonauts Yuri P. Gidzenko and Sergei K. Krikalev. Onboard the shuttle were STS-97 astronauts – commander Brent W. Jett, Jr., pilot Mike Bloomfield and mission specialists Marc Garneau of the Canadian Space Agency (CSA), Carlos I. Noriega and Joseph R. Tanner.

Pilot Bloomfield and Commander Jett talk with Dan Goldin

NASA Technical Reports Server (NTRS)

2000-01-01

Shortly after the landing of Endeavour, NASA Administrator Daniel Goldin (center) talks with STS-97 Pilot Michael Bloomfield (left) and Commander Brent Jett (right) underneath the orbiter. Landing occurred at 6:04 p.m. EST. On the 4.4-million-mile mission, Endeavour carried the P6 Integrated Truss Structure with solar arrays to power the International Space Station. The arrays and other equipment were installed during three EVAs that totaled 19 hours, 20 minutes. Endeavour was docked with the Space Station for 6 days, 23 hours, 13 minutes. This is the 16th nighttime landing for a Space Shuttle and the 53rd at Kennedy Space Center.

STS-97 ascent team in WFCR

NASA Image and Video Library

2000-11-20

JSC2000-07294 (20 November 2000) --- The 40-odd flight controllers assigned to the STS-97 ascent team and some special guests pose for a group portrait in the shuttle flight control room in Houston's Mission Control Center (JSC). The five guests attired in the blue and white shirts are the flight crew members for the STS-97 crew, scheduled to be launched from Florida on the last day of this month. The astronauts are, from the left, Joseph R. Tanner, Carlos I. Noriega, Brent W. Jett, Jr., Michael J. Bloomfield and Marc Garneau, who represents the Canadian Space Agency (CSA). Ascent shift flight director Wayne Hale stands next to Tanner.

The 2014 Annual(MCWG)Annual Metrology and Calibration Working Gr

NASA Image and Video Library

2014-05-07

Annual Metrology and Calibration Working Group Face to Face meeting held at Langley Research Center; Front Row (L to R): Stacy Sigmon – LaRC, Brent Watling – JSC, Ralph Hickman – WFF, Kirk Foster – MSFC, Don Wilson – SSC, Greg Boyd – JSC, Perry King – KSC, Bobby Price – GSFC, Felicia Donnell – GSFC, Perry LaRosa – GRC. Second Row (L to R): Ken Mathews – KSC, Darrell Shoup – WSTF, Gary Kennedy – MSFC, Terry Fleet – GRC, Damon Flansburg – ARC, Salvatore Tomaselli - WFF, Bruce Farner - SSC, David Scott – JPL, Jim Wachter – KSC, Shawn Britton – LaRC.

Flight in Adverse Environmental Condition

DTIC Science & Technology

1989-01-01

congruence among many accident studies that indicates that the flight crews have the opportunity to prevent 60-70% of all accidents 13]. Pigure 2 shows a...fully wendful of our duty ot car* and with thu roaliuAtion hm the undortndtng anA Xnaledgo gained vll not bo useful unl(ss the operational ayAtom can ex ...des donnles. Hls de cc ol tai les soutteent des mnimes ditauts Qua 13 tot-tle do PRtATT. En consiquence. 11 taut geot I lespnit quc !a description des

Comment to a paper of M. Villata on antigravity

NASA Astrophysics Data System (ADS)

Cabbolet, Marcoen J. T. F.

2012-01-01

In a recent paper of M. Villata, it is claimed that "antigravity appears as a prediction of general relativity when CPT is applied." However, the present paper argues that Villata puts the cart before the horse qua methodology, and that the resulting theory cannot be reconciled with the ontological presuppositions of general relativity. The conclusion is that Villata's suggestion for the physics that might underlie a gravitational repulsion of matter and antimatter is not acceptable as a fundamental theory in its current state of development.

Personologic alignment and the treatment of posttraumatic distress.

PubMed

Everly, G

2001-01-01

The therapeutic alliance is generally considered the sine qua non of successful psychotherapy. Yet, establishing the therapeutic alliance with patients suffering from syndromes of posttraumatic distress (including posttraumatic stress disorder) represents an unusual challenge. This paper describes the use of a personality-based approach to the establishment of the therapeutic alliance. This approach is referred to as personologic alignment and consists of alignment with preferential processes, as well as thematic belief systems. It represents an integration of the personology of Theodore Millon and the rhetoric of Aristotle.

Object Recognition Using Range Images.

DTIC Science & Technology

1985-12-01

and Reflectance Data to Find Planar Suface Regions," IEEE Transactions on Pattern Reco1iio n and Machine Intelligence , PAMI-l: 259-271 (July 1979...large number of data points. The dashed curve in the second through fourth qua- drants was drawn so as to parallel the curve in the first quadrant. One...find too much data . This lack of data has to do with the discri- mination ability of SDFs for objects of which the SDF’s are not composed. Thus for

Communitarian claims and community capabilities: furthering priority setting?

PubMed

Mooney, Gavin

2005-01-01

Priority setting in health care is generally not done well. This paper draws on ideas from Amartya Sen and Martha Nussbaum and adds some communitarian underpinnings to provide a way of improving on current uses of program budgeting and marginal analysis (PBMA) in priority setting. The paper suggests that shifting to a communitarian base for priority setting alters the distribution of property rights over health service decision making and increases the probability that recommendations from PBMA exercises will be implemented. The approach is built on a paradigm which departs from three tenets of welfarism as it is normally conceived: (i) individuals qua individuals seek to maximise their individual utility/well-being; (ii) individuals want to do this; and (iii) it is the values of individuals qua individuals that count. Some of the problems of PBMA, as it has been applied to date, are highlighted. It is argued that these are due largely to a lack of 'credible commitment'. Bringing in the community and communitarian values to PBMA priority setting exercises can help to overcome some of the barriers to getting PBMA recommendations implemented. The approach has the merit of reflecting Sen's concept of capabilities (but extending that to a community level). It avoids the often consequentialist base of a conventional welfarist framework, and it allows community values as opposed to individual values to come to the fore. How to elicit communitarian values is explored.

Guidance and Control Technology for Highly Integrated Systems.

DTIC Science & Technology

1981-02-08

fonctions. 11 s’agit en fait d’un probl ~me 6conomique de redondance du mat6riel et de redondance entre les sysemes - en ce qui concerne lea pannes, la...le brouillage pour lingual ii ne se pose qua le probl ~me de compatibilit6. 3 - La NIS bande L eat par contra envisag6 pour assurer in haut nivesu de... management considerably. The 5INTAC-3 is in the global system catenory : NIS L BAND + 3TID5 DTDMA optimized : - the message is distributed both For

Testing and Measurement Techniques in Heat Transfer and Combustion.

DTIC Science & Technology

1980-09-01

Is passage de lair de dilution au moyen d’une oeirie d’orlfices circu- laires , d’autre part leur propre refroidlseement grace A la cr~ation de films...dlenviron 20 % plus grand qua la valeur d~duite d’une meaure dana lair ambiant (en uti- lisant la loi en 273/T pour le nombre de mol~cules par unit6 de...question of possible bias of velocity measurement using a LDV when the seeding method is likely to produce nonuniformities of particle concentra- tion that

The Effect of Low Temperatures on Coated and Uncoated Fabrics,

DTIC Science & Technology

1982-03-01

pourcentage d’allongement et le travail a la rupture de treize tissus enduits et non enduits a fif 6tudig. Ii ressort qua les raglanges coton -matiires...C being a polyester and cotton blend, and N/C-G and N/C-F a nylon and cotton blend, N/C-F being the finished and dyed version of N/C-G. Fabrics N-R...and N-R-PU are similar ripatop nylons, N-R with water-repellent finish and N-R-PU with one side coated with polyurethan. For this study, N-R is

Non-Linear Aeroelastic Analyses and Testing,

DTIC Science & Technology

1981-07-01

anndes, eat une de ces indthodes. Il na sera pas ddcrit ici, parca qu’il a ddjA fait l’ob- jet de plusieurs publications, [7] A [101 , et nous nous...expdrimantala diffdranta d’un point A l’autre de Ia struc- ture. La prdsent exposE eat limitd A deux mdthodes qui ne prdsantent pas ce dernier inconvdnient...approprida, l’excitation doit donc possedar un minimum d’efficacitd pour lea modes qua V’on ddsire identifier. I - METHODE DE SYNTHESE HODALE La structure eat

Noninvasive Assessment of Cell Fate and Biology in Transplanted Mesenchymal Stem Cells.

PubMed

Franchi, Federico; Rodriguez-Porcel, Martin

2017-01-01

Recently, molecular imaging has become a conditio sine qua non for cell-based regenerative medicine. Developments in molecular imaging techniques, such as reporter gene technology, have increasingly enabled the noninvasive assessment of the fate and biology of cells after cardiovascular applications. In this context, bioluminescence imaging is the most commonly used imaging modality in small animal models of preclinical studies. Here, we present a detailed protocol of a reporter gene imaging approach for monitoring the viability and biology of Mesenchymal Stem Cells transplanted in a mouse model of myocardial ischemia reperfusion injury.

Environmental Assessment: Johnson County Road F-20 Bypass, Johnson County, Iowa.

DTIC Science & Technology

1986-08-01

D-A184 328 ENVIRONMENTAL ASSESSMENT- JOHNSON COUNTY ROAD F-20 vil BYPASS JOHNSON COUNTY’ IOWA (U) ARMY ENGINEER DISTRICT ROCK ISLAND IL AUG 86...BYPASS JOHNSON COUNTY, IOWA DTIC SELECTEI AUG 24 198D AUGUST 1986 -’"Thn; c>, .. i ’, been p ore i Icr publj rJlxaje aid sale; ii ,,. I distibu on is...2004 19 EPLY TO ATTENTION OP NCRPD-E ENVIRONMENTAL ASSE SSMENT JOHNSON COUNTY ROAD F-20 BYPASS JOHNSON COUNTY, IOWA Acce3siofl For NTIS MR& QUA~rTY

Federal funding of social work research: high hopes or sour grapes?

PubMed

Corvo, Kenneth; Chen, Wan-Yi; Selmi, Patrick

2011-07-01

Placed in the historical context of government funding ofacademic research, this critical analysis identifies the complexities and implications of schools of social work pursuing federal grants for research. Schools of social work with particular organizational characteristics are better able to compete for federal grants, incurring lower opportunity costs than others. The low probability of grant success for most schools, the organizational adaptations needed for success, and the narrow epistemology of many funding programs call into question whether federal funding of research should be considered the sine qua non for academic social work.

Hunting oil between elephants in Block 34/7 on the Norwegian shelf

DOE Office of Scientific and Technical Information (OSTI.GOV)

Elvsborg, A.; Nybakken, S.; Solli, T.

Block 34/7 is located east of the Statfjord field producing since 1979, and north of Gullfaks field, producing since 1986. Snorre field in the block should begin production in 1992. These three fields have more than 11 billion bbl in place and 5 billion bbl recoverable reserves. A heavy exploration program is done parallel to field development studies. The exploration activity is due to approaching relinquishment and securing tie-in to existing infrastructure. Because of extensive production facilities, small reserves can be used and all traps are now mapped and risk evaluated. So far, four discoveries have been made outside themore » Snorre field: Statfjord Oest Snorre Vest, C, and B. Estimated recoverable reserves are 400 million bbl. However, additional prospects could more than double these reserves. Exploration started with conventional structural traps. The two latest discoveries are pinch-out traps, and the next to be tested by wells are sealing fault traps. The East flank is a separate province downfaulted 2 km with several structures depending on sealing faults. New stratigraphy will be tested by the next well which is deviated to penetrate possible Lower Cretaceous and Upper Jurassic reservoir before reaching the main goal, which is the Brent reservoir. The result of this well could be very important for the opening of possible new play concepts in the northern North Sea. A sealing fault trap with Brent reservoir on the Tampen Spur will be tested by a well in 1990. Exploration is, however, in progress at several other stratigraphic levels within Tertiary, Upper and Lower Cretaceous, and other Upper Jurassic reservoirs where the possibilities for stratigraphic traps exist. These will be tested during next year's exploration program to secure potential reserves for field development at low production cost. Today, the minimum economic recoverable reserves in a prospect are 5-10 million bbl.« less

Centrifuge Impact Cratering Experiments

NASA Technical Reports Server (NTRS)

Schmidt, R. M.; Housen, K. R.; Bjorkman, M. D.

1985-01-01

The kinematics of crater growth, impact induced target flow fields and the generation of impact melt were determined. The feasibility of using scaling relationships for impact melt and crater dimensions to determine impactor size and velocity was studied. It is concluded that a coupling parameter determines both the quantity of melt and the crater dimensions for impact velocities greater than 10km/s. As a result impactor radius, a, or velocity, U cannot be determined individually, but only as a product in the form of a coupling parameter, delta U micron. The melt volume and crater volume scaling relations were applied to Brent crater. The transport of melt and the validity of the melt volume scaling relations are examined.

KSC-2011-7000

NASA Image and Video Library

2011-09-16

CAPE CANAVERAL, Fla. -- In the Press Site auditorium at NASA's Kennedy Space Center in Florida, Phil McAlister (left), director, Commercial Spaceflight Development in NASA’s Human Exploration and Operations Mission Directorate, and Brent Jeff, deputy director, Commercial Crew Program, brief representatives from aerospace industry partners and the media during a strategy forum on the next steps for NASA's Commercial Crew Program. The goal of the Commercial Crew Program is to have a commercially developed, human-capable, certified spacecraft safely flying astronauts into orbit and to the International Space Station by the middle of the decade. For more information about NASA's Commercial Crew Program, visit http://www.nasa.gov/exploration/commercial. Photo credit: NASA/Jim Grossmann

Training and information technology issue, 2005

DOE Office of Scientific and Technical Information (OSTI.GOV)

Agnihotri, Newal

The focus of the May-June issue is on training and information technology. Major articles/reports in this issue include: Communicating effectively, by Alain Bucaille, AREVA; Reputation management, by Susan Brisset, Bruce Power; Contol room and HSI modernization guidance, by Joseph Naser, EPRI; How far are we from public acceptance, by Jennifer A. Biedscheid and Murthy Devarakonda, Washington TRU Solutions LLC; Spent fuel management options, by Brent W. Dixon and Steven J. Piet, Idaho National Laboratory; Industry Awards; A secure energy future for America, by George W. Bush, President, United States of America; Vision of the future of nuclear energy, by Annemore » Lauvergeon, AREVA; and, Plant profile: strategy for transition to digital, TXU Power.« less

KSC-00padig100

NASA Image and Video Library

2000-11-27

After their arrival at the Shuttle Landing Facility, the STS-97 crew gather to address the media. At the microphone is Mission Specialist Carlos Noriega. Behind him stand Commander Brent Jett, Pilot Michael Bloomfield and Mission Specialists Joseph Tanner and Marc Garneau, who is with the Canadian Space Agency. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:06 p.m. EST

KSC00pp1753

NASA Image and Video Library

2000-11-27

At the Shuttle Landing Facility, Center Director Roy Bridges (left) greets STS-97 Commander Brent Jett on his arrival at KSC for the mission launch. At right is Mission Specialist Carlos Noriega. Jett and Noriega traveled from Johnson Space Center, Houston, Texas, in the T-38 jet aircraft behind them. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:06 p.m. EST

KSC-00pp1753

NASA Image and Video Library

2000-11-27

At the Shuttle Landing Facility, Center Director Roy Bridges (left) greets STS-97 Commander Brent Jett on his arrival at KSC for the mission launch. At right is Mission Specialist Carlos Noriega. Jett and Noriega traveled from Johnson Space Center, Houston, Texas, in the T-38 jet aircraft behind them. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:06 p.m. EST

KSC-00padig102

NASA Image and Video Library

2000-11-27

After their arrival at the Shuttle Landing Facility, the STS-97 crew gather to address the media. At the microphone is Mission Specialist Marc Garneau, who is with the Canadian Space Agency. Behind him stand Commander Brent Jett, Pilot Michael Bloomfield and Mission Specialists Joseph Tanner and Carlos Noriega. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:06 p.m. EST

KSC-00padig101

NASA Image and Video Library

2000-11-27

After their arrival at the Shuttle Landing Facility, the STS-97 crew gather to address the media. At the microphone is Mission Specialist Joseph Tanner. Behind him stand Commander Brent Jett, Pilot Michael Bloomfield and Mission Specialists Marc Garneau, who is with the Canadian Space Agency, and Carlos Noriega. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:06 p.m. EST

Endeavour's crew poses for a photo

NASA Technical Reports Server (NTRS)

2000-01-01

The STS-97 crew pauses for a photograph before heading for crew quarters. They landed safely at the SLF at 6:04 p.m. EST after a successful mission. From the left are Mission Specialists Joseph Tanner and Carlos Noriega, Commander Brent Jett, Pilot Michael Bloomfield and Mission Specialist Marc Garneau of Canada. Endeavour carried the P6 Integrated Truss Structure with solar arrays to power the International Space Station. The arrays and other equipment were installed during three EVAs that totaled 19 hours, 20 minutes. Endeavour was docked with the Space Station for 6 days, 23 hours, 13 minutes. This was the 16th nighttime landing for a Space Shuttle and the 53rd at Kennedy Space Center.

Auricular reconstruction for microtia: Part II. Surgical techniques.

PubMed

Walton, Robert L; Beahm, Elisabeth K

2002-07-01

Reconstruction of the microtic ear represents one of the most demanding challenges in reconstructive surgery. In this review the two most commonly used techniques for ear reconstruction, the Brent and Nagata techniques, are addressed in detail. Unique to this endeavor, the originator of each technique has been allowed to submit representative case material and to address the pros and cons of the other's technique. What follows is a detailed, insightful overview of microtia reconstruction, as a state of the art. The review then details commonly encountered problems in ear reconstruction and pertinent technical points. Finally, a glimpse into the future is offered with an accounting of the advances made in tissue engineering as this technology applies to auricular reconstruction.

STS-134 press conference with Mark Kelly

NASA Image and Video Library

2011-02-04

JSC2011-E-015241 (4 Feb. 2011) --- NASA astronaut Mark Kelly, STS-134 commander, listens to a reporter?s question during a news conference at NASA's Johnson Space Center. Seated next to Kelly are (left to right) Nicole Cloutier-Lemasters, public affairs officer; Brent Jett, Flight Crew Operations Directorate chief and Peggy Whitson, Astronaut Office chief. The briefing was held to discuss Kelly resuming training as the STS-134 shuttle mission commander. With the exception of some proficiency training, Kelly has been on personal leave since Jan. 8 to care for his wife, congresswoman Gabrielle Giffords, who was critically wounded in a Tucson, Ariz. shooting. Photo credit: NASA or National Aeronautics and Space Administration

STS-81 Flight Day 1

NASA Technical Reports Server (NTRS)

1997-01-01

This first day of the STS-81 mission begins with the flight crew, Cmdr. Michael A. Baker, Pilot Brent W. Jett, Mission Specialists, John M. Grunsfeld, Marsha S. Ivins, Peter J.K. Wisoff, and Jerry M. Linenger, performing pre-launch activities such as eating the traditional breakfast, being suited-up, and riding out to the launch pad. Also, included are various panoramic views of the shuttle on the pad. The crew is readied in the 'white room' for their mission. After the closing of the hatch and arm retraction, launch activities are shown including the countdown, engine ignition, and launch. The film ends with the separation of the Solid Rocket Boosters (SRB) from the shuttle.

STS-97 Mission Specialist Noriega talks to media after arrival for launch

NASA Technical Reports Server (NTRS)

2000-01-01

After their arrival at the Shuttle Landing Facility, the STS-97 crew gather to address the media. At the microphone is Mission Specialist Carlos Noriega. Behind him stand Commander Brent Jett, Pilot Michael Bloomfield and Mission Specialists Joseph Tanner and Marc Garneau, who is with the Canadian Space Agency. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:06 p.m. EST.

STS-97 Mission Specialist Tanner talks to media after arrival for launch

NASA Technical Reports Server (NTRS)

2000-01-01

After their arrival at the Shuttle Landing Facility, the STS-97 crew gather to address the media. At the microphone is Mission Specialist Joseph Tanner. Behind him stand Commander Brent Jett, Pilot Michael Bloomfield and Mission Specialists Marc Garneau, who is with the Canadian Space Agency, and Carlos Noriega. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:06 p.m. EST.

STS-97 Mission Specialist Garneau talks to media after arrival for launch

NASA Technical Reports Server (NTRS)

2000-01-01

After their arrival at the Shuttle Landing Facility, the STS-97 crew gather to address the media. At the microphone is Mission Specialist Marc Garneau, who is with the Canadian Space Agency. Behind him stand Commander Brent Jett, Pilot Michael Bloomfield and Mission Specialists Joseph Tanner and Carlos Noriega. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:06 p.m. EST.

KSC-97pc133

NASA Image and Video Library

1997-01-12

The STS-81 flight crew enjoys the traditional preliftoff breakfast in the crew quarters of the Operations and Checkout Building. They are (from left) Mission Specialist Marsha S. Ivins, Mission Commander Michael A. Baker; Pilot Brent W. Jett, Jr.; and Mission Specialists John M. Grunsfeld, Peter J. K. "Jeff" Wisoff; and J.M. "Jerry" Linenger. After a weather briefing, the flight crew will be fitted with their launch/entry suits and depart for Launch Pad 39B. Once there, they will take their positions in the crew cabin of the Space Shuttle Atlantis to await a liftoff during a seven-minute window that will open at 4:27 a.m. EST, January 12

Experimental measurements of seismic attenuation in microfracture sedimentary rock

DOE Office of Scientific and Technical Information (OSTI.GOV)

Peacock, S.; McCann, C.; Sothcott, J.

1994-09-01

In a previous paper (Peacock et al., 1994), the authors related ultrasonic velocities in water-saturated Carrara Marble to crack densities in polished sections to verify Hudson's (1980, 1981, 1986) theory for velocities in cracked rock. They describe the empirical relationships between attenuation and crack density that they established during these experiments in the hope of clarifying the mechanism of attenuation in rocks with fluid-filled cracks. Relating seismic velocity and attenuation to crack density is important in predicting the productivity of fractured petroleum reservoirs such as the North Sea Brent Field. It also allows cracks to be used as stress indicatorsmore » throughout the shallow crust (Crampin and Lovell, 1991).« less

Regulation and policy: International trends and issues

DOE Office of Scientific and Technical Information (OSTI.GOV)

Griffin, W S

As offshore oil and gas resources become exhausted, the associated production platforms and facilities will be decommissioned. The world-wide oil and gas industry is strictly regulated by global, regional and national guidelines which have been developed by governments to find the most responsible framework to perform the decommissioning. In the summer of 1995, the Brent Spar incident brought uncertainty to decommissioning world-wide. In June of 1995, a moratorium prohibiting sea disposal within the North East Atlantic was imposed by the Oslo Commission, and an unsuccessful attempt was made in December of 1995 to impose a world-wide moratorium on sea disposalmore » at the London Convention.« less

KSC-00pp1748

NASA Image and Video Library

2000-11-22

In the payload changeout room at Launch Pad 39B, STS-97 Commander Brent Jett (left), Mission Specialist Marc Garneau (center) and Pilot Michael Bloomfield (right) pause during a payload walkdown. The payload comprises the P6 Integrated Truss Segment, with solar arrays and batteries that will be temporarily installed on the recently delivered Z1 truss, connecting them to the Unity module. The two solar arrays are each more than 100 feet long. They will capture energy from the sun and convert it to power for the Station. Two spacewalks will be required to install the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:06 p.m. EST

How differential deflection of the inboard and outboard leading-edge flaps affected the handling qua

NASA Technical Reports Server (NTRS)

2002-01-01

How differential deflection of the inboard and outboard leading-edge flaps affected the handling qualities of this modified F/A-18A was evaluated during the first check flight in the Active Aeroelastic Wing program at NASA's Dryden Flight Research Center. The Active Aeroelastic Wing program at NASA's Dryden Flight Research Center seeks to determine the advantages of twisting flexible wings for primary maneuvering roll control at transonic and supersonic speeds, with traditional control surfaces such as ailerons and leading-edge flaps used to aerodynamically induce the twist. From flight test and simulation data, the program intends to develop structural modeling techniques and tools to help design lighter, more flexible high aspect-ratio wings for future high-performance aircraft, which could translate to more economical operation or greater payload capability. AAW flight tests began in November, 2002 with checkout and parameter-identification flights. Based on data obtained during the first flight series, new flight control software will be developed and a second series of research flights will then evaluate the AAW concept in a real-world environment. The program uses wings that were modified to the flexibility of the original pre-production F-18 wing. Other modifications include a new actuator to operate the outboard leading edge flap over a greater range and rate, and a research flight control system to host the aeroelastic wing control laws. The Active Aeroelastic Wing Program is jointly funded and managed by the Air Force Research Laboratory and NASA Dryden Flight Research Center, with Boeing's Phantom Works as prime contractor for wing modifications and flight control software development. The F/A-18A aircraft was provided by the Naval Aviation Systems Test Team and modified for its research role by NASA Dryden technicians.

Genetic Characterization of the Tick-Borne Orbiviruses

PubMed Central

Belaganahalli, Manjunatha N.; Maan, Sushila; Maan, Narender S.; Brownlie, Joe; Tesh, Robert; Attoui, Houssam; Mertens, Peter P. C.

2015-01-01

The International Committee for Taxonomy of Viruses (ICTV) recognizes four species of tick-borne orbiviruses (TBOs): Chenuda virus, Chobar Gorge virus, Wad Medani virus and Great Island virus (genus Orbivirus, family Reoviridae). Nucleotide (nt) and amino acid (aa) sequence comparisons provide a basis for orbivirus detection and classification, however full genome sequence data were only available for the Great Island virus species. We report representative genome-sequences for the three other TBO species (virus isolates: Chenuda virus (CNUV); Chobar Gorge virus (CGV) and Wad Medani virus (WMV)). Phylogenetic comparisons show that TBOs cluster separately from insect-borne orbiviruses (IBOs). CNUV, CGV, WMV and GIV share low level aa/nt identities with other orbiviruses, in ‘conserved’ Pol, T2 and T13 proteins/genes, identifying them as four distinct virus-species. The TBO genome segment encoding cell attachment, outer capsid protein 1 (OC1), is approximately half the size of the equivalent segment from insect-borne orbiviruses, helping to explain why tick-borne orbiviruses have a ~1 kb smaller genome. PMID:25928203

Genetic characterization of the tick-borne orbiviruses.

PubMed

Belaganahalli, Manjunatha N; Maan, Sushila; Maan, Narender S; Brownlie, Joe; Tesh, Robert; Attoui, Houssam; Mertens, Peter P C

2015-04-28

The International Committee for Taxonomy of Viruses (ICTV) recognizes four species of tick-borne orbiviruses (TBOs): Chenuda virus, Chobar Gorge virus, Wad Medani virus and Great Island virus (genus Orbivirus, family Reoviridae). Nucleotide (nt) and amino acid (aa) sequence comparisons provide a basis for orbivirus detection and classification, however full genome sequence data were only available for the Great Island virus species. We report representative genome-sequences for the three other TBO species (virus isolates: Chenuda virus (CNUV); Chobar Gorge virus (CGV) and Wad Medani virus (WMV)). Phylogenetic comparisons show that TBOs cluster separately from insect-borne orbiviruses (IBOs). CNUV, CGV, WMV and GIV share low level aa/nt identities with other orbiviruses, in 'conserved' Pol, T2 and T13 proteins/genes, identifying them as four distinct virus-species. The TBO genome segment encoding cell attachment, outer capsid protein 1 (OC1), is approximately half the size of the equivalent segment from insect-borne orbiviruses, helping to explain why tick-borne orbiviruses have a ~1 kb smaller genome.

Diffraction based overlay and image based overlay on production flow for advanced technology node

NASA Astrophysics Data System (ADS)

Blancquaert, Yoann; Dezauzier, Christophe

2013-04-01

One of the main challenges for lithography step is the overlay control. For the advanced technology node like 28nm and 14nm, the overlay budget becomes very tight. Two overlay techniques compete in our advanced semiconductor manufacturing: the Diffraction based Overlay (DBO) with the YieldStar S200 (ASML) and the Image Based Overlay (IBO) with ARCHER (KLA). In this paper we will compare these two methods through 3 critical production layers: Poly Gate, Contact and first metal layer. We will show the overlay results of the 2 techniques, explore the accuracy and compare the total measurement uncertainty (TMU) for the standard overlay targets of both techniques. We will see also the response and impact for the Image Based Overlay and Diffraction Based Overlay techniques through a process change like an additional Hardmask TEOS layer on the front-end stack. The importance of the target design is approached; we will propose more adapted design for image based targets. Finally we will present embedded targets in the 14 FDSOI with first results.

Short infrared laser pulses block action potentials in neurons

NASA Astrophysics Data System (ADS)

Walsh, Alex J.; Tolstykh, Gleb P.; Martens, Stacey L.; Ibey, Bennett L.; Beier, Hope T.

2017-02-01

Short infrared laser pulses have many physiological effects on cells including the ability to stimulate action potentials in neurons. Here we show that short infrared laser pulses can also reversibly block action potentials. Primary rat hippocampal neurons were transfected with the Optopatch2 plasmid, which contains both a blue-light activated channel rhodopsin (CheRiff) and a red-light fluorescent membrane voltage reporter (QuasAr2). This optogenetic platform allows robust stimulation and recording of action potential activity in neurons in a non-contact, low noise manner. For all experiments, QuasAr2 was imaged continuously on a wide-field fluorescent microscope using a Krypton laser (647 nm) as the excitation source and an EMCCD camera operating at 1000 Hz to collect emitted fluorescence. A co-aligned Argon laser (488 nm, 5 ms at 10Hz) provided activation light for CheRiff. A 200 mm fiber delivered infrared light locally to the target neuron. Reversible action potential block in neurons was observed following a short infrared laser pulse (0.26-0.96 J/cm2; 1.37-5.01 ms; 1869 nm), with the block persisting for more than 1 s with exposures greater than 0.69 J/cm2. Action potential block was sustained for 30 s with the short infrared laser pulsed at 1-7 Hz. Full recovery of neuronal activity was observed 5-30s post-infrared exposure. These results indicate that optogenetics provides a robust platform for the study of action potential block and that short infrared laser pulses can be used for non-contact, reversible action potential block.

Dedifferentiated Chondrosarcoma of the Larynx.

PubMed

Fidai, Shiraz S; Ginat, Daniel T; Langerman, Alexander J; Cipriani, Nicole A

2016-09-01

Primary dedifferentiated chondrosarcoma occurring in the larynx is a rare head and neck malignancy. The cases reported in the literature suggest male gender predilection and variable clinical outcomes ranging from disease-free survival to disease-related death. Although a calcified matrix is suggestive of chondrosarcoma, the dedifferentiated component is not readily appreciated on conventional imaging modalities and thorough tissue sampling is necessary for confirming the diagnosis. Histologically, there is an abrupt transition from a well-differentiated chondrosarcoma to a high-grade spindle cell component, which can show focal heterologous differentiation. These features are exemplified in this sine qua non radiology-pathology correlation article.

Incidences of the Restriction of the Bureaucratic Expense in the Venezuelan Public Sector (A Concrete Case the Venezuelan Air Force).

DTIC Science & Technology

1984-12-01

Venezolana de Administracion Publica, Vol. 3, 1984. 5. Carias, Brewer, La Reforma Institucional en Venezuela, El Nacional, 26 de enero 1976. 6. Easton...the form of an "iEnt-erprisel [{f~dte" In view of the magnitude of the investmonts of the government plan in accordance with the VI - in de la Na...ori all ose tD ia (?id ato s seeking a jo-b or positLion Lha t r- i~ *rrnc’, is a La ab( Lain bet te-r work qua3i Lv, and DL:rAnee F )T u s emp a oes

Correlates of adolescent assertiveness with HIV avoidance in a four-nation sample.

PubMed

Onuoha, Francis N; Munakata, Tsunetsugu

2005-01-01

Adolescents are frequently admonished to be socially assertive in order to confront negative interpersonal peer influences. Since the advent of HIV/AIDS in human social chemistry, the admonition has become more critical than ever. But the warning is often proffered in the misguided presumption that social assertiveness is the all-required psycho-structure against risk. The present cross-national study examines social and sexual assertiveness in four-country adolescent samples of Nigerian, Thai, Chinese, and Japanese college students. The findings reveal that sexual rather than social assertiveness was the sine qua non against risk, cross-culturally.

KSC-2011-6999

NASA Image and Video Library

2011-09-16

CAPE CANAVERAL, Fla. -- Representatives from aerospace industry partners and the media are given an overview on NASA's Commercial Crew Program's next steps during a strategy forum held in the Press Site auditorium at Kennedy Space Center in Florida. On the dais, from left, are Candrea Thomas, NASA Public Affairs; Phil McAlister, director, Commercial Spaceflight Development in NASA’s Human Exploration and Operations Mission Directorate, and Brent Jeff, deputy director, Commercial Crew Program. The goal of the Commercial Crew Program is to have a commercially developed, human-capable, certified spacecraft safely flying astronauts into orbit and to the International Space Station by the middle of the decade. For more information about NASA's Commercial Crew Program, visit http://www.nasa.gov/exploration/commercial. Photo credit: NASA/Jim Grossmann

Hack the Planet: What we Talk About When we Talk About Geoengineering

NASA Astrophysics Data System (ADS)

Kintisch, E.

2010-12-01

Hack the Planet (Wiley, 2010) explores how an idea once basically anathema to meetings like AGU has, in the space of a few years, become part of the geoscience mainstream. Through chapters involving researchers like David Battisti, Stephen Salter, Edward Teller and Brent Constanz the book documents the roots of this shift and how scientists are breaking new ground in the controversial field. And it shows how trying to engineer the planet's climate or manage its carbon poses novel scientific, geopolitical and moral risks and rewards. This session will cover how the topic of climate engineering has moved from something geoscientists don't talk about to something geoscientists can talk about, to something, in my view, that geoscientists must talk about.

KSC00pp1757

NASA Image and Video Library

2000-11-27

After arriving at the Shuttle Landing Facility, the STS-97 crew gather to address the media. At the microphone, Commander Brent Jett praises the efforts of the KSC workers to get ready for the launch. Behind Jett are Pilot Michael Bloomfield and Mission Specialists Joseph Tanner, Carlos Noriega and Marc Garneau, who is with the Canadian Space Agency. Mission STS-97 is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:06 p.m. EST

KSC-00padig098

NASA Image and Video Library

2000-11-27

After their arrival at the Shuttle Landing Facility, the STS-97 crew gather to address the media. At the microphone, Commander Brent Jett praises the efforts of the KSC workers to get ready for the launch. Behind Jett are Pilot Michael Bloomfield and Mission Specialists Joseph Tanner, Carolos Noriega and Marc Garneau, who is with the Canadian Space Agency. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:06 p.m. EST

KSC-00pp1757

NASA Image and Video Library

2000-11-27

After arriving at the Shuttle Landing Facility, the STS-97 crew gather to address the media. At the microphone, Commander Brent Jett praises the efforts of the KSC workers to get ready for the launch. Behind Jett are Pilot Michael Bloomfield and Mission Specialists Joseph Tanner, Carlos Noriega and Marc Garneau, who is with the Canadian Space Agency. Mission STS-97 is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:06 p.m. EST

KSC-00padig093

NASA Image and Video Library

2000-11-08

The STS-97 crew poses on the 215-foot level of the Fixed Service Structure during Terminal Countdown Demonstration Test activities that include emergency egress training, familiarization with the payload and a simulated launch countdown. From left, they are Mission Specialist Carlos Noriega, Commander Brent Jett, Pilot Mike Bloomfield, and Mission Specialists Marc Garneau and Joe Tanner. Mission STS-97 is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at 10:05 p.m. EST

Space Shuttle Projects

NASA Image and Video Library

1996-04-01

The crew assigned to the STS-78 mission included (seated left to right) Terrence T. (Tom) Henricks, commander; and Kevin R. Kregel, pilot. Standing, left to right, are Jean-Jacques Favier (CNES), payload specialist; Richard M. Linneham, mission specialist; Susan J. Helms, payload commander; Charles E. Brady, mission specialist; and Robert Brent Thirsk (CSA). Launched aboard the Space Shuttle Columbia on June 20, 1996 at 10:49:00 am (EDT), the STS-78 mission’s primary payloads was the Life and Microgravity Spacelab (LMS). Five space agencies (NASA/USA, European Space Agency/Europe (ESA), French Space Agency/France, Canadian Space Agency /Canada, and Italian Space Agency/Italy) along with research scientists from 10 countries worked together on the design, development and construction of the LMS.

KSC-97pc141

NASA Image and Video Library

1997-01-12

Greeted by cheers from wellwishers at KSC and eager for their venture into space on the fifth Shuttle-Mir docking mission, the STS-81 astronauts depart the Operations and Checkout Building on their way to Launch Pad 39B. Leading the six-member crew is Mission Commander Michael A. Baker, followed by Pilot Brent W. Jett, Jr. Behind them are Mission Specialists John M. Grunsfeld, Jerry Linenger, Peter J. K. "Jeff" Wisoff, and Marsha S. Ivins. Their trip to the pad will take about 25 minutes aboard the Astrovan. Once there, they will take their positions in the crew cabin of the Space Shuttle Atlantis to await a liftoff during a seven-minute window that will open at 4:27 a.m. EST, January 12

STS-81 launch view

NASA Image and Video Library

1998-06-15

STS081-S-007 (12 Jan. 1997) --- Framed by a silhouette of Florida foliage, the Space Shuttle Atlantis lifts off from Pad 39B at 4:27:23 a.m. (EST) Jan. 12, 1997 on its way for a docking mission with Russia's Mir Space Station. Onboard are six astronauts and a SPACEHAB Double Module (DM), along with a large supply of food, water, hardware and other materials for Mir. Astronaut Jerry M. Linenger, now onboard Atlantis, will trade places with John E. Blaha, cosmonaut guest researcher, onboard Mir since mid September 1996. Along with Linenger, other crewmembers now aboard Atlantis are astronauts Michael A. Baker, commander; Brent W. Jett, Jr., pilot; and mission specialists John M. Grunsfeld, Marsha S. Ivins and Peter J. K. (Jeff) Wisoff.

KSC-97pc140

NASA Image and Video Library

1997-01-12

Greeted by cheers from wellwishers at KSC and eager for their venture into space on the fifth Shuttle-Mir docking mission, the STS-81 astronauts depart the Operations and Checkout Building and board the Astrovan for their 25-minute trip to Launch Pad 39B. Leading the six-member crew is Mission Commander Michael A. Baker, followed by Pilot Brent W. Jett, Jr. Behind them are Mission Specialists John M. Grunsfeld, Jerry Linenger, Peter J. K. "Jeff" Wisoff, and Marsha S. Ivins. Once at the pad, they will take their positions in the crew cabin of the Space Shuttle Atlantis to await a liftoff during a seven-minute window that will open at 4:27 a.m. EST, January 12

STS-81 launch view

NASA Image and Video Library

1998-06-15

STS081-S-006 (12 Jan. 1997) --- The Space Shuttle Atlantis lifts off from Pad 39B at 4:27:23 a.m. (EST) Jan. 12, 1997 on its way for a docking mission with Russia's Mir Space Station. Onboard are six astronauts and a SPACEHAB Double Module (DM), along with a large supply of food, water, hardware and other materials for Mir. Astronaut Jerry M. Linenger, now onboard Atlantis, will trade places with John E. Blaha, cosmonaut guest researcher, onboard Mir since mid September 1996. Along with Linenger, other crewmembers now aboard Atlantis are astronauts Michael A. Baker, commander; Brent W. Jett, Jr., pilot; and mission specialists John M. Grunsfeld, Marsha S. Ivins and Peter J. K. (Jeff) Wisoff.

KSC-2012-5609

NASA Image and Video Library

2012-09-19

CAPE CANAVERAL, Fla. -- NASA's Commercial Crew Program, or CCP, hosts a pre-proposal conference to inform prospective companies about the recently released request for contract proposals and updates to the certification requirements for crewed missions to the International Space Station, or ISS. The two-phase certification process, called Certification Products Contract, or CPC, will enable NASA to eventually purchase service missions to fly astronauts to and from the ISS. From left, Ed Mango, CCP's program manager Steve Janney, CPC contracting officer Maria Collura, CCP certification manager Tom Simon, CPC Evaluation Team chair Brent Jett, CCP deputy program manager and Kathy Lueders, manager of the ISS Transportation Integration Office. To learn more about CCP, visit www.nasa.gov/commercialcrew. Photo credit: Kim Shiflett

KSC-2012-5603

NASA Image and Video Library

2012-09-19

CAPE CANAVERAL, Fla. -- NASA's Commercial Crew Program, or CCP, hosts a pre-proposal conference to inform prospective companies about the recently released request for contract proposals and updates to the certification requirements for crewed missions to the International Space Station, or ISS. The two-phase certification process, called Certification Products Contract, or CPC, will enable NASA to eventually purchase service missions to fly astronauts to and from the ISS. From left, Ed Mango, CCP's program manager Steve Janney, CPC contracting officer Maria Collura, CCP certification manager Tom Simon, CPC Evaluation Team chair Brent Jett, CCP deputy program manager and Kathy Lueders, manager of the ISS Transportation Integration Office. To learn more about CCP, visit www.nasa.gov/commercialcrew. Photo credit: Kim Shiflett

Endeavour's crew is greeted by Dan Goldin

NASA Technical Reports Server (NTRS)

2000-01-01

Following a successful landing, the crew of Endeavour exit the Crew Transport Vehicle and are greeted by NASA Administrator Daniel Goldin. First down the stairs is Commander Brent Jett. Behind him are Pilot Michael Bloomfield and Mission Specialists Joseph Tanner, Marc Garneau and Carlos Noriega. Garneau is with the Canadian Space Agency. On the 4.4-million-mile mission, Endeavour carried the P6 Integrated Truss Structure with solar arrays to power the International Space Station. The arrays and other equipment were installed during three EVAs that totaled 19 hours, 20 minutes. Endeavour was docked with the Space Station for 6 days, 23 hours, 13 minutes. This is the 16th nighttime landing for a Space Shuttle and the 53rd at Kennedy Space Center.

Climatology, Natural Cycles, and Modes of Interannual Variability of the Great Plains Low-Level Jet as Assimilated by the GEOS-1 Data Analysis System

NASA Technical Reports Server (NTRS)

Helfand, H. M.; Schubert, S. D.; Atlas, Robert (Technical Monitor)

2002-01-01

Despite the fact that the low-level jet of the southern Great Plains (the GPLLJ) of the U.S. is primarily a nocturnal phenomenon that virtually vanishes during the daylight hours, it is one of the most persistent and stable features of the low-level continental flow during the warm-season months, May through August. We have first used significant-level data to validate the skill of the GEOS-1 Data Assimilation System (DAS) in realistically detecting this jet and inferring its structure and evolution. We have then carried out a 15-year reanalysis with the GEOS-1 DAS to determine and validate its climatology and mean diurnal cycle and to study its interannual variability. Interannual variability of the GPLLJ is much smaller than mean diurnal and random intraseasonal variability and comparable in magnitude, but not location, to mean seasonal variability. There are three maxima of interannual low-level meridional flow variability of the GPLLJ over the upper Great Plains, southeastern Texas, and the western Gulf of Mexico. Cross-sectional profiles of mean southerly wind through the Texas maximum remain relatively stable and recognizable from year to year with only its eastward flank showing significant variability. This variability, however, exhibits a distinct, biennial oscillation during the first six years of the reanalysis period and only then. Each of the three variability maxima corresponds to a spatially coherent, jet-like pattern of low-level flow interannual variability. There are three prominent modes of interannual. variability. These include the intermittent biennial oscillation (IBO), local to the Texas maximum. Its signal is evident in surface pressure, surface temperature, ground wetness and upper air flow, as well. A larger-scale continental convergence pattern (CCP) of covariance, exhibiting strong anti-correlation between the flow near the Texas and the upper Great Plains variability maxima, is revealed only when the IBO is removed from the interannual

Sustainability of High Intensity Forest Management with Respect to Water QuaIity and Site Nutrient Reserves

Treesearch

Virginia R. Tolbert; Carl C. Trettin; Dale W. Johnson; John W. Parsons; Allan E. Houston; David A. Mays

2001-01-01

Ensuring sustainability of intensively managed woody crops requires determining soil and water quality effects using a combination of field data and modeling projections. Plot- and catchrnent-scale research, models, and meta-analyses are addressing nutrient availability, site quality, and measures to increase short-rotation woody crop (SRWC) productivity and site...

Neural pathways for visual speech perception

PubMed Central

Bernstein, Lynne E.; Liebenthal, Einat

2014-01-01

This paper examines the questions, what levels of speech can be perceived visually, and how is visual speech represented by the brain? Review of the literature leads to the conclusions that every level of psycholinguistic speech structure (i.e., phonetic features, phonemes, syllables, words, and prosody) can be perceived visually, although individuals differ in their abilities to do so; and that there are visual modality-specific representations of speech qua speech in higher-level vision brain areas. That is, the visual system represents the modal patterns of visual speech. The suggestion that the auditory speech pathway receives and represents visual speech is examined in light of neuroimaging evidence on the auditory speech pathways. We outline the generally agreed-upon organization of the visual ventral and dorsal pathways and examine several types of visual processing that might be related to speech through those pathways, specifically, face and body, orthography, and sign language processing. In this context, we examine the visual speech processing literature, which reveals widespread diverse patterns of activity in posterior temporal cortices in response to visual speech stimuli. We outline a model of the visual and auditory speech pathways and make several suggestions: (1) The visual perception of speech relies on visual pathway representations of speech qua speech. (2) A proposed site of these representations, the temporal visual speech area (TVSA) has been demonstrated in posterior temporal cortex, ventral and posterior to multisensory posterior superior temporal sulcus (pSTS). (3) Given that visual speech has dynamic and configural features, its representations in feedforward visual pathways are expected to integrate these features, possibly in TVSA. PMID:25520611

Measuring efficiency of international crude oil markets: A multifractality approach

NASA Astrophysics Data System (ADS)

Niere, H. M.

2015-01-01

The three major international crude oil markets are treated as complex systems and their multifractal properties are explored. The study covers daily prices of Brent crude, OPEC reference basket and West Texas Intermediate (WTI) crude from January 2, 2003 to January 2, 2014. A multifractal detrended fluctuation analysis (MFDFA) is employed to extract the generalized Hurst exponents in each of the time series. The generalized Hurst exponent is used to measure the degree of multifractality which in turn is used to quantify the efficiency of the three international crude oil markets. To identify whether the source of multifractality is long-range correlations or broad fat-tail distributions, shuffled data and surrogated data corresponding to each of the time series are generated. Shuffled data are obtained by randomizing the order of the price returns data. This will destroy any long-range correlation of the time series. Surrogated data is produced using the Fourier-Detrended Fluctuation Analysis (F-DFA). This is done by randomizing the phases of the price returns data in Fourier space. This will normalize the distribution of the time series. The study found that for the three crude oil markets, there is a strong dependence of the generalized Hurst exponents with respect to the order of fluctuations. This shows that the daily price time series of the markets under study have signs of multifractality. Using the degree of multifractality as a measure of efficiency, the results show that WTI is the most efficient while OPEC is the least efficient market. This implies that OPEC has the highest likelihood to be manipulated among the three markets. This reflects the fact that Brent and WTI is a very competitive market hence, it has a higher level of complexity compared against OPEC, which has a large monopoly power. Comparing with shuffled data and surrogated data, the findings suggest that for all the three crude oil markets, the multifractality is mainly due to long

The power of silver: age and identity politics in the 21st century.

PubMed

Gilleard, Chris; Higgs, Paul

2009-01-01

Pensioner political movements emerged in the interwar years in America and Europe. Documentary and empirical analyses confirm the influential role such movements played in helping shape the postwar social security systems of Western societies. Pensioner movements, qua pensioner movements, have failed to retain their influence, despite that "old age" and its demographic significance have become more salient. We propose three explanations for this: the first concerns the failure of old age to connect with the generational ethos of identity politics; the second reflects the nature of the actors now involved in the governance of old age; and the third concerns the individualization of retirement as a phase of life.

Bioethics, biotechnology and culture: a voice from the margins.

PubMed

Tangwa, Godfrey B

2004-12-01

In this paper I argue for the universality of morality as against and in spite of the plurality and inevitable relativity of human cultures. Universalisability is the litmus test of moral authenticity whereas culture tends to impose an egocentric predicament. I argue equally for the equality of cultures qua cultures and of the importance of different cultural perspectives, given the limitations of each and every particular culture, in a balanced and wholesome appreciation of moral issues, particularly issues of cross-cultural relevance. I then try to anchor my reflections on a few topical ethical issues of cross-cultural relevance which have been the subject of controversy in recent times.

Synthesis of Asynchronous Systems from Data Flow Specifications

DTIC Science & Technology

1993-12-01

Sarma B. K. Vrudhula, UA-ECE ISI/RR-93-366 December 1993 DTIC S ELECTE APR 2 81994 U G D!MC QUA& f n MC’W". 1 S INFORMATION SCIENCES 3101822-1511...wire data types is denoted by nb, where n is a positive integer. 3. Group data types are denoted by (g1,g2,.. . , g ,), where each gi is a null data type...During the manipulation of a DFG, a data type may be reduced to an equiv- alent data type. (gl) is equivalent to g1 , and (g1,g2,. . . , g 3 i--9,g9,gj+1

KSC-00padig090

NASA Image and Video Library

2000-11-08

Commander Brent Jett looks toward Pilot Mike Broomfield, on his right, as they get comfortable in their seats in the cockpit of Space Shuttle Endeavour on Launch Pad 39B. Along with the rest of the crew, they are taking part in a simulated launch countdown, part of Terminal Countdown Demonstration Test activities that also include emergency egress training and familiarization with the payload. Mission STS-97 is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:05 p.m. EST

KSC-00pp1674

NASA Image and Video Library

2000-11-08

The STS-97 crew heads for the Astrovan and a ride to Launch Pad 39B as they continue Terminal Countdown Demonstration Test (TCDT) activities. Seen left to right are Mission Specialists Joe Tanner, Carlos Noriega and Marc Garneau; Pilot Mike Bloomfield; and Commander Brent Jett. The TCDT provides emergency egress training, a simulated launch countdown and opportunities to inspect the mission payloads in the orbiter’s payload bay. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at 10:05 p.m. EST

STS-72 Liftoff viewed from left side of Pad 39B

NASA Technical Reports Server (NTRS)

1996-01-01

The Space Shuttle Endeavour lights up the night sky as it thunders aloft from Launch Pad 39B. Liftoff of Mission STS- 72 occurred at 4:41:00.072 am EST, January 11, kicking off the 1996 Shuttle launch schedule. On board Endeavour are a crew of six: Commander Brian Duffy; Pilot Brent W. Jett; and Mission Specialists Dr. Daniel T. Barry, Leroy Chiao, Winston E. Scott, and Koichi Wakata, who represents the National Space Development Agency (NASDA) of Japan. During their planned nine-day mission, the crew will retrieve the Japanese Space Flyer Unit (SFU), deploy and later retrieve the Office of Aeronautics and Space Technology-Flyer (OAST- Flyer), and conduct two extravehicular activities (EVAs). STS-72 is the 74th Shuttle mission and the 10th flight of the orbiter Endeavour.

STS-97 crew looks over the payload from the Payload Changeout Room

NASA Technical Reports Server (NTRS)

2000-01-01

Members of the STS-97 crew look into Endeavour'''s payload bay at some of the equipment that will be carried on the mission. At far left are (left to right) Commander Brent Jett and Mission Specialist Joseph Tanner, with a technician. At center are Mission Specialists Marc Garneau and Carlos Noriega, plus Pilot Michael Bloomfield. The equipment visible at right are the orbiter docking system (ODS) (center) and Canadian robotic arm (left and below the ODS). The arm will be used during spacewalks on the mission to install solar arrays. Each more than 100 feet long, the arrays will capture energy from the sun and convert it to power for the Station. STS-97 is scheduled to launch Nov. 30 at about 10:06 p.m. EST.

KSC-2012-1265

NASA Image and Video Library

2012-02-07

CAPE CANAVERAL, Fla. -- Commercial Crew Program (CCP) Manager Ed Mango, left, and Deputy Program Manager Brent Jett host a Program Strategy Forum at NASA's Kennedy Space Center in Florida. The forum was held to update industry partners about NASA's next phase of developing commercial space transportation system capabilities. CCP is helping to mature the design and development of a crew transportation system with the overall goal of accelerating a United States-led capability to the International Space Station. The goal of the program is to drive down the cost of space travel as well as open up space to more people than ever before by balancing industry’s own innovative capabilities with NASA's 50 years of human spaceflight experience. For more information, visit www.nasa.gov/commercialcrew. Photo credit: NASA/Kim Shiflett

Overlay accuracy with respect to device scaling

NASA Astrophysics Data System (ADS)

Leray, Philippe; Laidler, David; Cheng, Shaunee

2012-03-01

Overlay metrology performance is usually reported as repeatability, matching between tools or optics aberrations distorting the measurement (Tool induced shift or TIS). Over the last few years, improvement of these metrics by the tool suppliers has been impressive. But, what about accuracy? Using different target types, we have already reported small differences in the mean value as well as fingerprint [1]. These differences make the correctables questionable. Which target is correct and therefore which translation, scaling etc. values should be fed back to the scanner? In this paper we investigate the sources of these differences, using several approaches. First, we measure the response of different targets to offsets programmed in a test vehicle. Second, we check the response of the same overlay targets to overlay errors programmed into the scanner. We compare overlay target designs; what is the contribution of the size of the features that make up the target? We use different overlay measurement techniques; is DBO (Diffraction Based Overlay) more accurate than IBO (Image Based Overlay)? We measure overlay on several stacks; what is the stack contribution to inaccuracy? In conclusion, we offer an explanation for the observed differences and propose a solution to reduce them.

Achieving optimum diffraction based overlay performance

NASA Astrophysics Data System (ADS)

Leray, Philippe; Laidler, David; Cheng, Shaunee; Coogans, Martyn; Fuchs, Andreas; Ponomarenko, Mariya; van der Schaar, Maurits; Vanoppen, Peter

2010-03-01

Diffraction Based Overlay (DBO) metrology has been shown to have significantly reduced Total Measurement Uncertainty (TMU) compared to Image Based Overlay (IBO), primarily due to having no measurable Tool Induced Shift (TIS). However, the advantages of having no measurable TIS can be outweighed by increased susceptibility to WIS (Wafer Induced Shift) caused by target damage, process non-uniformities and variations. The path to optimum DBO performance lies in having well characterized metrology targets, which are insensitive to process non-uniformities and variations, in combination with optimized recipes which take advantage of advanced DBO designs. In this work we examine the impact of different degrees of process non-uniformity and target damage on DBO measurement gratings and study their impact on overlay measurement accuracy and precision. Multiple wavelength and dual polarization scatterometry are used to characterize the DBO design performance over the range of process variation. In conclusion, we describe the robustness of DBO metrology to target damage and show how to exploit the measurement capability of a multiple wavelength, dual polarization scatterometry tool to ensure the required measurement accuracy for current and future technology nodes.

Communicating data quality through Web Map Services

NASA Astrophysics Data System (ADS)

Blower, Jon; Roberts, Charles; Griffiths, Guy; Lewis, Jane; Yang, Kevin

2013-04-01

The sharing and visualization of environmental data through spatial data infrastructures is becoming increasingly common. However, information about the quality of data is frequently unavailable or presented in an inconsistent fashion. ("Data quality" is a phrase with many possible meanings but here we define it as "fitness for purpose" - therefore different users have different notions of what constitutes a "high quality" dataset.) The GeoViQua project (www.geoviqua.org) is developing means for eliciting, formatting, discovering and visualizing quality information using ISO and Open Geospatial Consortium (OGC) standards. Here we describe one aspect of the innovations of the GeoViQua project. In this presentation, we shall demonstrate new developments in using Web Map Services to communicate data quality at the level of datasets, variables and individual samples. We shall outline a new draft set of conventions (known as "WMS-Q"), which describe a set of rules for using WMS to convey quality information (OGC draft Engineering Report 12-160). We shall demonstrate these conventions through new prototype software, based upon the widely-used ncWMS software, that applies these rules to enable the visualization of uncertainties in raster data such as satellite products and the results of numerical simulations. Many conceptual and practical issues have arisen from these experiments. How can source data be formatted so that a WMS implementation can detect the semantic links between variables (e.g. the links between a mean field and its variance)? The visualization of uncertainty can be a complex task - how can we provide users with the power and flexibility to choose an optimal strategy? How can we maintain compatibility (as far as possible) with existing WMS clients? We explore these questions with reference to existing standards and approaches, including UncertML, NetCDF-U and Styled Layer Descriptors.

Next generation laser-based standoff spectroscopy techniques for Mars exploration.

PubMed

Gasda, Patrick J; Acosta-Maeda, Tayro E; Lucey, Paul G; Misra, Anupam K; Sharma, Shiv K; Taylor, G Jeffrey

2015-01-01

In the recent Mars 2020 Rover Science Definition Team Report, the National Aeronautics and Space Administration (NASA) has sought the capability to detect and identify elements, minerals, and most importantly, biosignatures, at fine scales for the preparation of a retrievable cache of samples. The current Mars rover, the Mars Science Laboratory Curiosity, has a remote laser-induced breakdown spectroscopy (LIBS) instrument, a type of quantitative elemental analysis, called the Chemistry Camera (ChemCam) that has shown that laser-induced spectroscopy instruments are not only feasible for space exploration, but are reliable and complementary to traditional elemental analysis instruments such as the Alpha Particle X-Ray Spectrometer. The superb track record of ChemCam has paved the way for other laser-induced spectroscopy instruments, such as Raman and fluorescence spectroscopy. We have developed a prototype remote LIBS-Raman-fluorescence instrument, Q-switched laser-induced time-resolved spectroscopy (QuaLITy), which is approximately 70 000 times more efficient at recording signals than a commercially available LIBS instrument. The increase in detection limits and sensitivity is due to our development of a directly coupled system, the use of an intensified charge-coupled device image detector, and a pulsed laser that allows for time-resolved measurements. We compare the LIBS capabilities of our system with an Ocean Optics spectrometer instrument at 7 m and 5 m distance. An increase in signal-to-noise ratio of at least an order of magnitude allows for greater quantitative analysis of the elements in a LIBS spectrum with 200-300 μm spatial resolution at 7 m, a Raman instrument capable of 1 mm spatial resolution at 3 m, and bioorganic fluorescence detection at longer distances. Thus, the new QuaLITy instrument fulfills all of the NASA expectations for proposed instruments.

Bridge over the River Qua: Using Simulations to Span the Divide between Prelaw and Political Science Students

ERIC Educational Resources Information Center

Woessner, Matthew; Winters, Kathleen H.; Kopko, Kyle C.

2017-01-01

Undergraduate public law courses often attract students with competing expectations. Some students enroll in these courses to prepare for law school, while others enroll in the courses to gain a broader understanding of courts in the American system of government. These differing student constituencies can create a dilemma for instructors. A…

Deconstructing mammalian reproduction: using knockouts to define fertility pathways.

PubMed

Roy, Angshumoy; Matzuk, Martin M

2006-02-01

Reproduction is the sine qua non for the propagation of species and continuation of life. It is a complex biological process that is regulated by multiple factors during the reproductive life of an organism. Over the past decade, the molecular mechanisms regulating reproduction in mammals have been rapidly unraveled by the study of a vast number of mouse gene knockouts with impaired fertility. The use of reverse genetics to generate null mutants in mice through targeted disruption of specific genes has enabled researchers to identify essential regulators of spermatogenesis and oogenesis in vivo and model human disorders affecting reproduction. This review focuses on the merits, utility, and the variations of the knockout technology in studies of reproduction in mammals.

New data on polymorphism of the meadow spittlebug Philaenus spumarius (L.) (Hemiptera: Aphrophoridae) from the island of São Miguel (Azores).

PubMed

Borges, Paulo A V; Rodrigues, Ana S B; Silva, Sara E; Seabra, Sofia G; Paulo, OctÁvio S; Quartau, JosÉ A

2018-01-02

The meadow spittlebug, Philaenus spumarius (L.) (Hemiptera, Aphrophoridae) is a widespread insect species in the Holarctic region, exhibiting a dorsal colour balanced polymorphism. In the Azores the species is known from high elevations in Terceira and São Miguel islands. A sample of 235 individuals from Pico da Vara and Graminhais protected areas (São Miguel, Azores) (between 645 and 935 m a.s.l.), collected in 2000 and 2017, showed a remarkable high frequency of the melanic morphs flavicollis (FLA) and quadrimaculatus (QUA). In addition, a high frequency of melanics was observed in males. We explore the hypotheses for the origin of Azorean colonization and for the high proportion of melanism in the Azorean populations.

The detection of Vaccinia virus confirms the high circulation of Orthopoxvirus in buffaloes living in geographical isolation, Marajó Island, Brazilian Amazon.

PubMed

Franco-Luiz, Ana Paula Moreira; Fagundes Pereira, Alexandre; de Oliveira, Cairo Henrique Sousa; Barbosa, José Diomedes; Oliveira, Danilo Bretas; Bonjardim, Cláudio Antônio; Ferreira, Paulo César Peregrino; de Souza Trindade, Giliane; Abrahão, Jônatas Santos; Kroon, Erna Geessien

2016-06-01

In Brazil, serologic evidence of Orthopoxvirus (OPV) circulation showed positivity around 20% in cattle, humans, monkeys and rodents. Although OPV seropositivity has been described in buffalo herds in southeastern Brazil, no Vaccinia virus (VACV) (member of genus OPV) outbreaks in buffalo herds have been described in this country. This study aimed to investigate the detection of anti-OPV antibodies and to study the OPV genome in Brazilian buffalo herds. Our results demonstrated a high OPV seropositivity in buffalo herds on Marajó Island and molecular data confirmed the circulation of VACV. The geographical isolation conditionmight be a sine qua non condition to explain our results. Copyright © 2016. Published by Elsevier Ltd.

What is the Essence of Hypnosis?

PubMed

Dell, Paul F

2017-01-01

The author explores the nature of hypnosis, which he characterizes as a motivated mode of neural functioning that enables most humans to alter, to varying degrees, their experience of body, self, actions, and world. The essence of hypnosis is not to be found in hetero-hypnosis; instead, it lies in the spontaneous self-activation of that mode of neural functioning. The hypnosis field has substantially lost sight of spontaneous self-activation, because the word hypnosis is usually used to mean hetero-hypnosis. Self-activation of this mode of neural functioning is the necessary sine qua non of hypnotic psychopathology. Moreover, self-activation of trance is the characteristic hypnotic behavior of a distinct subset of highly hypnotizable individuals.

KSC-00pp1647

NASA Image and Video Library

2000-11-07

KENNEDY SPACE CENTER, Fla. -- STS-97 Commander Brent Jett listens to a question from a reporter during a media session near Launch Pad 39B. The crew is at KSC to take part in Terminal Countdown Demonstration Test activities that include emergency egress training, familiarization with the payload, and a simulated launch countdown. The other crew members are Pilot Mike Bloomfield and Mission Specialists Joe Tanner, Marc Garneau and Carlos Noriega. Garneau is with the Canadian Space Agency. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:05 p.m. EST

Joint in-flight portrait of the STS-81 and Mir 22 crew on Mir

NASA Image and Video Library

1997-02-26

STS081-369-003 (12-22 Jan. 1997) --- Traditional inflight crew portrait of the combined Mir-22 and STS-81 crews in the Base Block Module aboard Russia's Mir Space Station. Front row: left to right, Michael A. Baker, commander; John M. Grunsfeld, mission specialist; and cosmonaut Aleksandr Y. Kaleri, Mir-22 flight engineer. Middle row: cosmonaut Valeri G. Korzun, Mir-22 commander; Marsha S. Ivins, mission specialist; and John E. Blaha, former cosmonaut guest researcher. Back row: Jerry M. Linenger, cosmonaut guest researcher; Peter J. K. (Jeff) Wisoff, mission specialist; and Brent W. Jett, Jr., pilot. Linenger is seen in a Russian jump suit, and Blaha now wears a Space Shuttle inflight garment as the two exchanged cosmonaut guest researcher roles on January 14, 1997, following the docking of the Atlantis and the Mir complex.

STS-81 launch view

NASA Image and Video Library

1998-06-15

STS081-S-005 (12 Jan. 1997) --- Lighting up an early morning sky, the Space Shuttle Atlantis lifts off from Pad 39B to begin the new year of space missions for NASA's shuttle fleet. Launch occurred at 4:27:23 a.m. (EST), Jan. 12, 1997. Now on their way for a docking mission with Russia's Mir Space Station are a crew of six astronauts and a SPACEHAB Double Module (DM), along with a large supply of food, water, hardware and other materials for Mir. Astronaut Jerry M. Linenger, now onboard Atlantis, will trade places with John E. Blaha, cosmonaut guest researcher, onboard Mir since mid September 1996. Along with Linenger, other crewmembers now aboard Atlantis are astronauts Michael A. Baker, commander; Brent W. Jett, Jr., pilot; and mission specialists John M. Grunsfeld, Marsha S. Ivins and Peter J. K. (Jeff) Wisoff.

STS-72 Flight Day 2

NASA Technical Reports Server (NTRS)

1996-01-01

On this second day of the STS-72 mission, the flight crew, Cmdr. Brian Duffy, Pilot Brent W. Jett, and Mission Specialists Leroy Chiao, Daniel T. Barry, Winston E. Scott, and Koichi Wakata (NASDA), awakened to music from the motion picture 'Star Wars.' The crew performed a systems checkout, prepared for the retrieval of the Japanese Space Flyer Unit (SFU), tested the spacesuits for the EVA, and activated some of the secondary experiments. An in-orbit news interview was conducted with the crew via satellite downlinking. Questions asked ranged from the logistics of the mission to the avoidance procedures the Endeavour Orbiter performed to miss hitting the inactive Air Force satellite, nicknamed 'Misty' (MSTI). Earth views included cloud cover, several storm systems, and various land masses with several views of the shuttle's open cargo bay in the foreground.

Near-Earth Asteroids: Destinations for Human Exploration

NASA Technical Reports Server (NTRS)

Barbee, Brent W.

2014-01-01

The Near-Earth Object Human Space Flight Accessible Targets Study (NHATS) is a system that monitors the near-Earth asteroid (NEA) population to identify NEAs whose orbital characteristics may make them potential destinations for future round-trip human space flight missions. To accomplish this monitoring, Brent Barbee (GSFC) developed and automated a system that applies specialized trajectory processing to the orbits of newly discovered NEAs, and those for which we have updated orbit knowledge, obtained from the JPL Small Bodies Database (SBDB). This automated process executes daily and the results are distributed to the general public and the astronomy community. This aids in prioritizing telescope radar time allocations for obtaining crucial follow-up observations of highly accessible NEAs during the critical, because it is often fleeting, time period surrounding the time at which the NEAs are initially discovered.

STS-97 crew meets with the media at Launch Pad 39B

NASA Technical Reports Server (NTRS)

2000-01-01

STS-97 Commander Brent Jett listens to a question from a reporter during a media session near Launch Pad 39B. The crew is at KSC to take part in Terminal Countdown Demonstration Test activities that include emergency egress training, familiarization with the payload, and a simulated launch countdown. The other crew members are Pilot Mike Bloomfield and Mission Specialists Joe Tanner, Marc Garneau and Carlos Noriega. Garneau is with the Canadian Space Agency. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:05 p.m. EST.

STS-97 crew meets with the media at Launch Pad 39B

NASA Technical Reports Server (NTRS)

2000-01-01

During Terminal Countdown Demonstration Test (TCDT) activities, the STS-97 crew pause in the White Room at Launch Pad 39B for a photo. At left is Commander Brent Jett and crouching in front is Pilot Mike Bloomfield. Standing behind him are Mission Specialists Joe Tanner, Marc Garneau and Carlos Noriega. . Garneau is with the Canadian Space Agency. The TCDT includes emergency egress training, familiarization with the payload, and a simulated launch countdown. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at 10:05 p.m. EST.

STS-97 crew meets with the media at Launch Pad 39B

NASA Technical Reports Server (NTRS)

2000-01-01

From the slidewire landing zone at Launch Pad 39B, STS-97 Mission Specialist Carlos Noriega (at right, with microphone) describes the mission for the media. Next to him are Mission Specialists Joe Tanner (left) and Marc Garneau (center). The crew is at KSC to take part in Terminal Countdown Demonstration Test activities that include emergency egress training, familiarization with the payload, and a simulated launch countdown. The other crew members are Commander Brent Jett and Pilot Mike Bloomfield. Mission STS- 97is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:05 p.m. EST.

The use of diagnostic ratios, biomarkers and 3-way Kohonen neural networks to monitor the temporal evolution of oil spills.

PubMed

Fernández-Varela, R; Gómez-Carracedo, M P; Ballabio, D; Andrade, J M

2015-07-15

Oil spill identification relies usually on a wealth of chromatographic data which requires advanced data treatment (chemometrics). A simple approach based on Kohonen neural networks to handle three-dimensional arrays is presented. A suite of 28 diagnostic ratios was considered to monitor six oils along four months. It was found that some traditional diagnostic ratios were not stable enough. In particular, alkylated PAHs (e.g. 1-methyldibenzothiophene, 4-methylpyrene, 27bbSTER and the TA21 and TA26 triaromatic steroids) seemed less resistant to medium-weathering than biomarkers. One (or two) ratios were found to differentiate each product: 30O, 28ab (and 25nor30ab), C3-dbt/C3-phe, 27Ts, TA26 and 29Ts characterized Ashtart, Brent, Maya, Sahara, IFO and Prestige oils, respectively. Copyright © 2015 Elsevier Ltd. All rights reserved.

Faltering lemming cycles reduce productivity and population size of a migratory Arctic goose species

PubMed Central

Nolet, Bart A; Bauer, Silke; Feige, Nicole; Kokorev, Yakov I; Popov, Igor Yu; Ebbinge, Barwolt S

2013-01-01

1. The huge changes in population sizes of Arctic-nesting geese offer a great opportunity to study population limitation in migratory animals. In geese, population limitation seems to have shifted from wintering to summering grounds. There, in the Arctic, climate is rapidly changing, and this may impact reproductive performance, and perhaps population size of geese, both directly (e.g. by changes in snow melt) or indirectly (e.g. by changes in trophic interactions). 2. Dark-bellied brent geese (Branta bernicla bernicla L.) increased 20-fold since the 1950s. Its reproduction fluctuates strongly in concert with the 3-year lemming cycle. An earlier analysis, covering the growth period until 1988, did not find evidence for density dependence, but thereafter the population levelled off and even decreased. The question is whether this is caused by changes in lemming cycles, population density or other factors like carry-over effects. 3. Breeding success was derived from proportions of juveniles. We used an information-theoretical approach to investigate which environmental factors best explained the variation in breeding success over nearly 50 years (1960–2008). We subsequently combined GLM predictions of breeding success with published survival estimates to project the population trajectory since 1991 (year of maximum population size). In this way, we separated the effects of lemming abundance and population density on population development. 4. Breeding success was mainly dependent on lemming abundance, the onset of spring at the breeding grounds, and the population size of brent goose. No evidence was found for carry-over effects (i.e. effects of conditions at main spring staging site). Negative density dependence was operating at a population size above c. 200 000 individuals, but the levelling off of the population could be explained by faltering lemming cycles alone. 5. Lemmings have long been known to affect population productivity of Arctic-nesting migratory

Faltering lemming cycles reduce productivity and population size of a migratory Arctic goose species.

PubMed

Nolet, Bart A; Bauer, Silke; Feige, Nicole; Kokorev, Yakov I; Popov, Igor Yu; Ebbinge, Barwolt S

2013-07-01

The huge changes in population sizes of Arctic-nesting geese offer a great opportunity to study population limitation in migratory animals. In geese, population limitation seems to have shifted from wintering to summering grounds. There, in the Arctic, climate is rapidly changing, and this may impact reproductive performance, and perhaps population size of geese, both directly (e.g. by changes in snow melt) or indirectly (e.g. by changes in trophic interactions). Dark-bellied brent geese (Branta bernicla bernicla L.) increased 20-fold since the 1950s. Its reproduction fluctuates strongly in concert with the 3-year lemming cycle. An earlier analysis, covering the growth period until 1988, did not find evidence for density dependence, but thereafter the population levelled off and even decreased. The question is whether this is caused by changes in lemming cycles, population density or other factors like carry-over effects. Breeding success was derived from proportions of juveniles. We used an information-theoretical approach to investigate which environmental factors best explained the variation in breeding success over nearly 50 years (1960-2008). We subsequently combined GLM predictions of breeding success with published survival estimates to project the population trajectory since 1991 (year of maximum population size). In this way, we separated the effects of lemming abundance and population density on population development. Breeding success was mainly dependent on lemming abundance, the onset of spring at the breeding grounds, and the population size of brent goose. No evidence was found for carry-over effects (i.e. effects of conditions at main spring staging site). Negative density dependence was operating at a population size above c. 200 000 individuals, but the levelling off of the population could be explained by faltering lemming cycles alone. Lemmings have long been known to affect population productivity of Arctic-nesting migratory birds and, more

Chemical composition, functional and sensory characteristics of wheat-taro composite flours and biscuits.

PubMed

Himeda, Makhlouf; Njintang Yanou, Nicolas; Fombang, Edith; Facho, Balaam; Kitissou, Pierre; Mbofung, Carl M F; Scher, Joel

2014-09-01

The physicochemical, alveographic and sensory characteristics of precooked taro-wheat composite flours and their biscuits were investigated. A 2x7 factorial design consisting of two varieties of taro flour (Red Ibo Ngaoundere, RIN, and egg-like varieties) and 7 levels of wheat substitutions (0, 5, 10, 15, 20, 25 and 30 %) was used for this purpose. It was observed that water absorption capacity (range 95-152 g/100 g), water solubility index (range 18.8-29.5 g/100 g) and swelling capacity (range 125.4-204.6 mL/100 g) of composite flours significantly (p < 0.05) increased with increase in taro level. Conversely the dough elasticity index (range 59.8-0 %), extensibility (78-22 mm) and strength (range 281-139 × 10(-4) joules) significantly (p < 0.05) diminished with increase in wheat substitution. Up to 10 % substitution with RIN taro flour and 15 % with egg-like taro flour, the composite taro-wheat dough exhibited elasticity indices acceptable for the production of baking products, whereas at all levels of taro substitution, the composite biscuits samples were either acceptable as or better (5-10 % substitution with RIN flour) than 100 % wheat biscuit.

Advanced overlay analysis through design based metrology

NASA Astrophysics Data System (ADS)

Ji, Sunkeun; Yoo, Gyun; Jo, Gyoyeon; Kang, Hyunwoo; Park, Minwoo; Kim, Jungchan; Park, Chanha; Yang, Hyunjo; Yim, Donggyu; Maruyama, Kotaro; Park, Byungjun; Yamamoto, Masahiro

2015-03-01

As design rule shrink, overlay has been critical factor for semiconductor manufacturing. However, the overlay error which is determined by a conventional measurement with an overlay mark based on IBO and DBO often does not represent the physical placement error in the cell area. The mismatch may arise from the size or pitch difference between the overlay mark and the cell pattern. Pattern distortion caused by etching or CMP also can be a source of the mismatch. In 2014, we have demonstrated that method of overlay measurement in the cell area by using DBM (Design Based Metrology) tool has more accurate overlay value than conventional method by using an overlay mark. We have verified the reproducibility by measuring repeatable patterns in the cell area, and also demonstrated the reliability by comparing with CD-SEM data. We have focused overlay mismatching between overlay mark and cell area until now, further more we have concerned with the cell area having different pattern density and etch loading. There appears a phenomenon which has different overlay values on the cells with diverse patterning environment. In this paper, the overlay error was investigated from cell edge to center. For this experiment, we have verified several critical layers in DRAM by using improved(Better resolution and speed) DBM tool, NGR3520.

Hybrid overlay metrology for high order correction by using CDSEM

NASA Astrophysics Data System (ADS)

Leray, Philippe; Halder, Sandip; Lorusso, Gian; Baudemprez, Bart; Inoue, Osamu; Okagawa, Yutaka

2016-03-01

Overlay control has become one of the most critical issues for semiconductor manufacturing. Advanced lithographic scanners use high-order corrections or correction per exposure to reduce the residual overlay. It is not enough in traditional feedback of overlay measurement by using ADI wafer because overlay error depends on other process (etching process and film stress, etc.). It needs high accuracy overlay measurement by using AEI wafer. WIS (Wafer Induced Shift) is the main issue for optical overlay, IBO (Image Based Overlay) and DBO (Diffraction Based Overlay). We design dedicated SEM overlay targets for dual damascene process of N10 by i-ArF multi-patterning. The pattern is same as device-pattern locally. Optical overlay tools select segmented pattern to reduce the WIS. However segmentation has limit, especially the via-pattern, for keeping the sensitivity and accuracy. We evaluate difference between the viapattern and relaxed pitch gratings which are similar to optical overlay target at AEI. CDSEM can estimate asymmetry property of target from image of pattern edge. CDSEM can estimate asymmetry property of target from image of pattern edge. We will compare full map of SEM overlay to full map of optical overlay for high order correction ( correctables and residual fingerprints).

KSC-00padig081

NASA Image and Video Library

2000-11-06

The STS-97 crew pose for a photo on the parking area of the Shuttle Landing Facility after their arrival in the T-38 jet aircraft behind them. From left, they are Mission Specialist Carlos Noriega, Joe Tanner and Marc Garneau (with the Canadian Space Agency); Commander Brent Jett; and Pilot Mike Bloomfield. The crew is at KSC to take part in Terminal Countdown Demonstration Test activities that include emergency egress training, familiarization with the payload, and a simulated launch countdown. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:05 p.m. EST

KSC-00pp1675

NASA Image and Video Library

2000-11-08

The STS-97 crew get a taste of the excitement of launch day as they exit the O&C Building to head for Launch Pad 39B. They are taking part in Terminal Countdown Demonstration Test (TCDT) activities that include emergency egress training and a simulated launch countdown. On the left (front to back) are Mission Specialists Carlos Noriega and Joe Tanner; on the right (front to back) are Commander Brent Jett, Pilot Mike Bloomfield and Mission Specialist Marc Garneau, who is a Canadian astronaut. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at 10:05 p.m. EST

KSC-00pp1655

NASA Image and Video Library

2000-11-07

The STS-97 crew gets instruction on use of the slidewire basket during emergency egress training on the 195-foot level at Launch Pad 39B. On the left are Mission Specialists Joe Tanner and Marc Garneau and Pilot Mike Bloomfield. On the right are Commander Brent Jett (foreground) and Mission Specialist Carlos Noriega (behind Jett). The training is part of Terminal Countdown Demonstration Test (TCDT) activities, which also include a simulated launch countdown and opportunities to inspect the mission payloads in the orbiter’s payload bay. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at 10:05 p.m. EST

The predictive content of CBOE crude oil volatility index

NASA Astrophysics Data System (ADS)

Chen, Hongtao; Liu, Li; Li, Xiaolei

2018-02-01

Volatility forecasting is an important issue in the area of econophysics. The information content of implied volatility for financial return volatility has been well documented in the literature but very few studies focus on oil volatility. In this paper, we show that the CBOE crude oil volatility index (OVX) has predictive ability for spot volatility of WTI and Brent oil returns, from both in-sample and out-of-sample perspectives. Including OVX-based implied volatility in GARCH-type volatility models can improve forecasting accuracy most of time. The predictability from OVX to spot volatility is also found for longer forecasting horizons of 5 days and 20 days. The simple GARCH(1,1) and fractionally integrated GARCH with OVX performs significantly better than the other OVX models and all 6 univariate GARCH-type models without OVX. Robustness test results suggest that OVX provides different information from as short-term interest rate.

2016 American Conference on Neutron Scattering (ACNS)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Woodward, Patrick

The 8th American Conference on Neutron Scattering (ACNS) was held July 10-14, 2016 in Long Beach California, marking the first time the meeting has been held on the west coast. The meeting was coordinated by the Neutron Scattering Society of America (NSSA), and attracted 285 attendees. The meeting was chaired by NSSA vice president Patrick Woodward (the Ohio State University) assisted by NSSA president Stephan Rosenkranz (Argonne National Laboratory) together with the local organizing chair, Brent Fultz (California Institute of Technology). As in past years the Materials Research Society assisted with planning, logistics and operation of the conference. The sciencemore » program was divided into the following research areas: (a) Sources, Instrumentation, and Software; (b) Hard Condensed Matter; (c) Soft Matter; (d) Biology; (e) Materials Chemistry and Materials for Energy; (f) Engineering and Industrial Applications; and (g) Neutron Physics.« less

STS-97 and Expedition One crewmembers pose for a photo in the Service Module

NASA Image and Video Library

2000-12-08

STS097-326-031 (8 December 2000)--- When the five STS-97 astronauts paid a visit to the three Expedition 1 crew members onboard the International Space Station (ISS), they all posed for a traditional in-flight portrait, albeit for the first time in the Zvezda Service Module. On the front row are (left to right) astronauts Brent W. Jett, Jr., STS-97 commander; William M. Shepherd, Expedition 1 mission commander; and Joseph R. Tanner, STS-97 mission specialist. On the second row are (from the left) cosmonaut Sergei K. Krikalev, Expedition 1 flight engineer; astronaut Carlos I. Noriega, STS-97 mission specialist; cosmonaut Yuri P. Gidzenko, Expedition 1 Soyuz commander; and astronaut Michael J. Bloomfield, STS-97 pilot. Behind them is astronaut Marc Garneau, STS-97 mission specialist representing the Canadian Space Agency (CSA). Krikalev and Gidzenko represent the Russian Aviation and Space Agency.

STS-97 and Expedition One crewmembers pose for a photo in the Service Module

NASA Image and Video Library

2000-12-08

STS097-313-001 (8 December 2000)--- When the five STS-97 astronauts paid a visit to the three Expedition 1 crew members onboard the International Space Station (ISS), they all posed for a traditional in-flight portrait, albeit for the first time in the Zvezda Service Module. On the front row are (left to right) astronauts Brent W. Jett, Jr., STS-97 commander; William M. Shepherd, Expedition 1 mission commander; and Joseph R. Tanner, STS-97 mission specialist. On the second row are (from the left) cosmonaut Sergei K. Krikalev, Expedition 1 flight engineer; astronaut Carlos I. Noriega, STS-97 mission specialist; cosmonaut Yuri P. Gidzenko, Expedition 1 Soyuz commander; and astronaut Michael J. Bloomfield, STS-97 pilot. Behind them is astronaut Marc Garneau, STS-97 mission specialist representing the Canadian Space Agency (CSA). Krikalev and Gidzenko represent the Russian Aviation and Space Agency.

The STS-97 crew leaves O&C for Launch Pad 39B

NASA Technical Reports Server (NTRS)

2000-01-01

The STS-97 crew leaves the O&C Building on their way to Launch Pad 39B for a simulated launch countdown. Commander Brent Jett (right) leads the way with Pilot Mike Bloomfield behind him. Taking up the rear are (left) Mission Specialists Carlos Noriega, Joe Tanner and (right) Marc Garneau, who is with the Canadian Space Agency. The crew is taking part in Terminal Countdown Demonstration Test activities that include emergency egress training, familiarization with the payload, and the simulated launch countdown. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:05 p.m. EST.

The STS-97 crew meets with the media at Launch Pad 39B

NASA Technical Reports Server (NTRS)

2000-01-01

The STS-97 crew pose for photographers at the base of Launch Pad 39B. They are, left to right, Commander Brent Jett, Pilot Mike Bloomfield and Mission Specialists Carlos Noriega, Marc Garneau and Joe Tanner. Garneau is with the Canadian Space Agency. The crew is at KSC to take part in Terminal Countdown Demonstration Test activities that include emergency egress training, familiarization with the payload, and a simulated launch countdown. Visible in the background are the solid rocket booster and external tank on Space Shuttle Endeavour. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:05 p.m. EST.

[The question of interdisciplinary work in the daily work of a nurse in a mental health day care center].

PubMed

Mello, R

1998-01-01

This study aim is the nurses perceptions inside the mental health daily attention centre and the interdisciplinary aspect their work. This study has emerged from the necessity of understanding the work and participation of the nurses who act in those new places together with a interdisciplinary group, taking into consideration that graduation does not educate nurses for this kind of work. The interdisciplinary work has been seen as a sine qua non condition for optimising care for people who suffer from serious psychological illness as it is in the II National Conference of Mental Health, the Caracas Conference and the Health Ministry 224 Edict. Quantitative study has been used in order to value each nurse experience as well as his/her professional history in Mental Care Exercise.

The ethics of good communication in a complex research partnership.

PubMed

Sodeke, Stephen; Turner, Timothy; Tarver, Will

2010-08-01

The tripartite partnership among Morehouse School of Medicine, Tuskegee University, and University of Alabama at Birmingham is complex. In 2005, the three schools--with different institutional cultures, characters, and resources--agreed to collaborate in efforts to eliminate racial/ethnic disparities in cancer burdens. Pursuing this laudable aim predictably involved some miscommunication. The Bioethics Shared Resource (BSR) group foresaw such challenges and monitored interactions to prevent harm, noting that while effective communication is critical to the achievement of mutual goals, an understanding and prudent use of proven communication principles is a sine qua non for success. In this commentary, we share the undergirding moral concepts, communication approaches, and lessons learned. This experience has led us to propose an ethics of good communication for others to consider.

The Ethics of Good Communication in a Complex Research Partnership

PubMed Central

Sodeke, Stephen; Turner, Timothy; Tarver, Will

2013-01-01

The tripartite partnership among Morehouse School of Medicine, Tuskegee University, and University of Alabama at Birmingham is complex. In 2005, the three schools—with different institutional cultures, characters, and resources—agreed to collaborate in efforts to eliminate racial/ethnic disparities in cancer burdens. Pursuing this laudable aim predictably involved some miscommunication. The Bioethics Shared Resource (BSR) group foresaw such challenges and monitored interactions to prevent harm, noting that while effective communication is critical to the achievement of mutual goals, an understanding and prudent use of proven communication principles is a sine qua non for success. In this commentary, we share the undergirding moral concepts, communication approaches, and lessons learned. This experience has led us to propose an ethics of good communication for others to consider. PMID:20675944

Two-wave model of the muscle contraction.

PubMed

Molski, Marcin

2009-05-01

The Matsuno model of the muscle contraction is considered in the framework of the two-wave Corben's theory of composite objects built up of both time- and space-like components. It has been proved that during muscle contraction the locally coherent aggregates distributed along the actin filament interact by means of space-like fields, which are solutions of the relativistic Feinberg equation. The existence of such interactions and lack of decoherence are conditions sine qua non for appearance of the quantum entanglement between actin monomers in an ATP-activated filament. A possible role of a quantum potential in the muscle contraction is discussed and the mass of the carrier of space-like interactions is estimated m0' = 7.3 x 10(-32) g (46 eV).

A Reconnaissance Study as a "Sine Qua Non Factor" for Status Quo Change among Senior Phase Technology Teachers

ERIC Educational Resources Information Center

Mapotse, Tomé Awshar

2015-01-01

This article is based on a preliminary action research (AR) study conducted with selected schools in Limpopo. It intends to report on the progress made and research problem identified during the reconnaissance/preliminary study. The aim of this preliminary research is to ascertain whether the findings conform to the main research question of the…

KSC00pp1657

NASA Image and Video Library

2000-11-07

The STS-97 crew listens to a trainer explain use of the slidewire basket (right) for emergency egress from the Fixed Service Structure. Second from left is Mission Specialist Joe Tanner; next to him in the cap is Capt. George Hoggard, safety trainer with the KSC Fire Department; Pilot Mike Bloomfield; Mission Specialist Carlos Noriega; Commander Brent Jett; and Mission Specialist Marc Garneau. The training is part of Terminal Countdown Demonstration Test (TCDT) activities, which also include a simulated launch countdown and opportunities to inspect the mission payloads in the orbiter’s payload bay. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at 10:05 p.m. EST

KSC-00pp1657

NASA Image and Video Library

2000-11-07

The STS-97 crew listens to a trainer explain use of the slidewire basket (right) for emergency egress from the Fixed Service Structure. Second from left is Mission Specialist Joe Tanner; next to him in the cap is Capt. George Hoggard, safety trainer with the KSC Fire Department; Pilot Mike Bloomfield; Mission Specialist Carlos Noriega; Commander Brent Jett; and Mission Specialist Marc Garneau. The training is part of Terminal Countdown Demonstration Test (TCDT) activities, which also include a simulated launch countdown and opportunities to inspect the mission payloads in the orbiter’s payload bay. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at 10:05 p.m. EST

Hardware Implementation of 32-Bit High-Speed Direct Digital Frequency Synthesizer

PubMed Central

Ibrahim, Salah Hasan; Ali, Sawal Hamid Md.; Islam, Md. Shabiul

2014-01-01

The design and implementation of a high-speed direct digital frequency synthesizer are presented. A modified Brent-Kung parallel adder is combined with pipelining technique to improve the speed of the system. A gated clock technique is proposed to reduce the number of registers in the phase accumulator design. The quarter wave symmetry technique is used to store only one quarter of the sine wave. The ROM lookup table (LUT) is partitioned into three 4-bit sub-ROMs based on angular decomposition technique and trigonometric identity. Exploiting the advantages of sine-cosine symmetrical attributes together with XOR logic gates, one sub-ROM block can be removed from the design. These techniques, compressed the ROM into 368 bits. The ROM compressed ratio is 534.2 : 1, with only two adders, two multipliers, and XOR-gates with high frequency resolution of 0.029 Hz. These techniques make the direct digital frequency synthesizer an attractive candidate for wireless communication applications. PMID:24991635

KSC-00pp1680

NASA Image and Video Library

2000-11-08

During Terminal Countdown Demonstration Test (TCDT) activities at Launch Pad 39B, the STS-97 crew poses for a photo at the 215-foot level. From left, they are Mission Specialist Carlos Noriega, Commander Brent Jett, Pilot Mike Bloomfield and Mission Specialists Marc Garneau and Joe Tanner. Behind them at left can be seen the top of the solid rocket booster and external tank on Space Shuttle Endeavour. The TCDT includes emergency egress training, opportunities to inspect the mission payloads in the orbiter’s payload bay and a simulated launch countdown. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at 10:05 p.m. EST

STS-97 crew poses for photo on Launch Pad 39B

NASA Technical Reports Server (NTRS)

2000-01-01

During Terminal Countdown Demonstration Test (TCDT) activities at Launch Pad 39B, the STS-97 crew poses for a photo at the 215-foot level. From left, they are Mission Specialist Carlos Noriega, Commander Brent Jett, Pilot Mike Bloomfield and Mission Specialists Marc Garneau and Joe Tanner. Behind them at left can be seen the top of the solid rocket booster and external tank on Space Shuttle Endeavour. The TCDT includes emergency egress training, opportunities to inspect the mission payloads in the orbiter'''s payload bay and a simulated launch countdown. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at 10:05 p.m. EST.

KSC-00pp1781

NASA Image and Video Library

2000-11-30

With the help of a suit technician, STS-97 Commander Brent Jett dons his launch and entry suit. This is his third Shuttle flight.; Mission STS-97 is the sixth construction flight to the International Space Station. It is transporting the P6 Integrated Truss Structure that comprises Solar Array Wing-3 and the Integrated Electronic Assembly, to be installed on the Space Station. The solar arrays are mounted on a “blanket” that can be folded like an accordion for delivery. Once in orbit, astronauts will deploy the blankets to their full size. The 11-day mission includes two spacewalks to complete the solar array connections. The Station’s electrical power system will use eight photovoltaic solar arrays, each 112 feet long by 39 feet wide, to convert sunlight to electricity. Gimbals will be used to rotate the arrays so that they will face the Sun to provide maximum power to the Space Station. Launch is scheduled for Nov. 30 at 10:06 p.m. EST

STS-81 Post Flight Presentation

NASA Technical Reports Server (NTRS)

1997-01-01

The flight crew of the STS-81 mission, Commander Michael A. Baker, Pilot Brent W. Jett Jr, and Mission Specialists John M. Grunsfeld, Marsha S. Ivins, Peter J.K. Wisoff, and Jerry M. Linenger present a video mission over-view of their space flight. Images include prelaunch activities such as eating the traditional breakfast, crew suit-up, and the ride out to the launch pad. Also included are various panoramic views of the shuttle on the pad. The crew can be seen being readied in the "white room" for their mission. After the closing of the hatch and arm retraction, launch activities are shown including countdown, engine ignition, launch, and the separation of the Solid Rocket Boosters. During the presentation the astronauts take turns discussing aspects of the mission including: the SPACEHAB a double module that provides additional middeck locker space for secondary experiments. During the five days of docked operations with Mir, the crews is seen transferring water and supplies from one spacecraft to the other.

Treatment of fingertip amputation: comparison of results between microsurgical replantation and pocket principle.

PubMed

Yabe, Tetsuji; Tsuda, Tomoyuki; Hirose, Shunsuke; Ozawa, Toshiyuki

2012-05-01

In this article, a comparison of replantation using microsurgical replantation (replantation) and the Brent method and its modification (pocket principle) in the treatment of fingertip amputation is reported. As a classification of amputation level, we used Ishikawa's subzone classification of fingertip amputation, and the cases of amputations only in subzone 2 were included in this study. Between these two groups, there was no statistical difference in survival rate, postoperative atrophy, or postoperative range of motion. In terms of sensory recovery, some records were lost and exact study was difficult. But there was no obvious difference between these cases. In our comparison of microsurgical replantation versus the pocket principle in treatment of subzone 2 fingertip amputation, there was no difference in postoperative results. Each method has pros and cons, and the surgeon should choose which technique to use based on his or her understanding of the characteristics of both methods. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

KSC-00pp1664

NASA Image and Video Library

2000-11-07

Workers in the Space Station Processing Facility gather with the crew of mission STS-97, who are holding the symbolic key representing the turnover of the P6 Integrated Truss Structure, part of the payload on their mission. During the ceremony the P6 truss segment was transferred from International Space Station ground operations to the NASA shuttle integration team. Commander Brent Jett (second from right) received the key in the ceremony. Standing with him are (left to right) Mission Specialists Marc Garneau, Joe Tanner and Carlos Noriega, at left; and Pilot Mike Bloomfield, at right. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission involves two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at 10:05 p.m. EST

STS-97 crew meets with the media at Launch Pad 39B

NASA Technical Reports Server (NTRS)

2000-01-01

Standing in the slidewire landing zone at Launch Pad 39B, the STS-97 crew respond to questions from the media. They are, left to right, Commander Brent Jett, Pilot Mike Bloomfield and Mission Specialists Joe Tanner, Marc Garneau and Carlos Noriega. Garneau is with the Canadian Space Agency. The nets suspended behind them are a braking system catch net for the slidewire baskets that provide emergency exit from the orbiter and Fixed Service Structure. The crew is at KSC to take part in Terminal Countdown Demonstration Test activities that include emergency egress training, familiarization with the payload, and a simulated launch countdown. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at 10:05 p.m. EST.

Multifractal detrended cross-correlation analysis on gold, crude oil and foreign exchange rate time series

NASA Astrophysics Data System (ADS)

Pal, Mayukha; Madhusudana Rao, P.; Manimaran, P.

2014-12-01

We apply the recently developed multifractal detrended cross-correlation analysis method to investigate the cross-correlation behavior and fractal nature between two non-stationary time series. We analyze the daily return price of gold, West Texas Intermediate and Brent crude oil, foreign exchange rate data, over a period of 18 years. The cross correlation has been measured from the Hurst scaling exponents and the singularity spectrum quantitatively. From the results, the existence of multifractal cross-correlation between all of these time series is found. We also found that the cross correlation between gold and oil prices possess uncorrelated behavior and the remaining bivariate time series possess persistent behavior. It was observed for five bivariate series that the cross-correlation exponents are less than the calculated average generalized Hurst exponents (GHE) for q<0 and greater than GHE when q>0 and for one bivariate series the cross-correlation exponent is greater than GHE for all q values.

The unfinished assignment: Educating Moroccan women for development

NASA Astrophysics Data System (ADS)

Belhachmi, Zakia

1987-12-01

Western theories of development, and the resulting strategies and planning represent major structural barriers to Moroccan Women's Liberation. The author advocates a shift from current anti-participatory strategies to a new people-oriented approach, emphasizing the multiple roles of women within an integrated strategy. This involves linking educational projects with other parts of the infrastructure. Morocco's `way out' of exogenous development, the author contends, is contingent upon an adequate management of the educational system both at the institutional and personal levels. Therefore, educating women can be considered a sine qua non in optimizing conditions leading to endogenous development. The foundation is the establishment or strengthening of a whole infrastructure for the creation, transmission, and application of alternative methods likely to sustain socio-economic opportunities leading to Morocco's self-reliance.

Cellular growth in plants requires regulation of cell wall biochemistry.

PubMed

Chebli, Youssef; Geitmann, Anja

2017-02-01

Cell and organ morphogenesis in plants are regulated by the chemical structure and mechanical properties of the extracellular matrix, the cell wall. The two primary load bearing components in the plant cell wall, the pectin matrix and the cellulose/xyloglucan network, are constantly remodelled to generate the morphological changes required during plant development. This remodelling is regulated by a plethora of loosening and stiffening agents such as pectin methyl-esterases, calcium ions, expansins, and glucanases. The tight spatio-temporal regulation of the activities of these agents is a sine qua non condition for proper morphogenesis at cell and tissue levels. The pectin matrix and the cellulose-xyloglucan network operate in concert and their behaviour is mutually dependent on their chemical, structural and mechanical modifications. Copyright © 2017 Elsevier Ltd. All rights reserved.

The origin of life in a cosmic context

NASA Technical Reports Server (NTRS)

Sagan, C.

1974-01-01

It is shown that there is at present no aspect of contemporary biology where the contingent can be distinguished from the necessary, or the evolutionary accident from the biological sine qua non; and no amount of terrestrial experimentation alone is likely to make such distinctions possible. Hence, biology suffers from a deadening parochialism, much like the physics of falling bodies before Newton showed that the same laws applied to the motion of apples in England and to the planets about the sun. The deparochialization of biology can only come in the same way and must therefore await the search for extraterrestrial life. It is in this sense that the significance of explorations of the planets and their satellites, asteroids, comets, and the interplanetary medium for the origin of life is assessed.

STEM Beyond The Classroom: Creating Authentic Outreach Programs That Build Bridges Between The Classroom And Real World Challenges

NASA Astrophysics Data System (ADS)

Ibarra, D. L.; Forder, S. E.; Pritchard, M.

2014-12-01

The ISF Academy was founded by Charles Kao, a Nobel Prize laureate. In 2011, the Shuyuan programs were established at The ISF Academy to operate both as a "school within a school" and as a "school outside the classroom." The Shuyuan programs work together with the IBO Science and Technology subject areas to develop comprehensive and challenging opportunities that address the 14 Grand Engineering Challenges. The goal is to establish co-curricular programs that go beyond the taught curriculum and support STEM curricula. Several programs outside of the classroom include an onsite robotics researcher, underwater and land based robotics programs, field trips, whole school food waste composting and the implementation of an energy tracking system. Relationships with several local universities allow students to work closely with professors in research settings and, annually, a leading researcher gives a keynote speech to our students. Other signature Shuyuan programs have developed international strategic relationships with the NRI at Cambridge University, where students spend several weeks studying science and civilization in China using primary source materials. Additionally, Shuyuan has supported extension opportunities for classroom teachers with institutional partnerships that include the British Council, governmental organizations, local universities, corporations, and NGOs. In conclusion, the overall goal of the Shuyuan Programs is to provide experiential learning opportunities that challenge conventional curriculum design in a manner that is supportive and innovative!

Use of a 12 months' self-referral reminder to facilitate uptake of bowel scope (flexible sigmoidoscopy) screening in previous non-responders: a London-based feasibility study.

PubMed

Kerrison, Robert S; McGregor, Lesley M; Marshall, Sarah; Isitt, John; Counsell, Nicholas; Wardle, Jane; von Wagner, Christian

2016-03-29

In March 2013, NHS England extended its national Bowel Cancer Screening Programme to include 'one-off' Flexible Sigmoidoscopy screening (NHS Bowel Scope Screening, BSS) for men and women aged 55. With less than one in two people currently taking up the screening test offer, there is a strong public health mandate to develop system-friendly interventions to increase uptake while the programme is rolling out. This study aimed to assess the feasibility of sending a reminder to previous BSS non-responders, 12 months after the initial invitation, with consideration for its potential impact on uptake. This study was conducted in the ethnically diverse London Boroughs of Brent and Harrow, where uptake is below the national average. Between September and November 2014, 160 previous non-responders were randomly selected to receive a reminder of the opportunity to self-refer 12 months after their initial invitation. The reminder included instructions on how to book an appointment, and provided options for the time and day of the appointment and the gender of the endoscopist performing the test. To address barriers to screening, the reminder was sent with a brief locally tailored information leaflet designed specifically for this study. Participants not responding within 4 weeks were sent a follow-up reminder, after which there was no further intervention. Self-referral rates were measured 8 weeks after the delivery of the follow-up reminder and accepted as final. Of the 155 participants who received the 12 months' reminder (returned to sender, n=5), 30 (19.4%) self-referred for an appointment, of which 24 (15.5%) attended and were successfully screened. Attendance rates differed by gender, with significantly more women attending an appointment than men (20.7% vs 8.8%, respectively; OR=2.73, 95% CI=1.02-7.35, P=0.05), but not by area (Brent vs Harrow) or area-level deprivation. Of the 30 people who self-referred for an appointment, 27 (90%) indicated a preference for a same

A code of ethics for health care ethics consultants: journey to the present and implications for the field.

PubMed

Tarzian, Anita J; Wocial, Lucia D

2015-01-01

For decades a debate has played out in the literature about who bioethicists are, what they do, whether they can be considered professionals qua bioethicists, and, if so, what professional responsibilities they are called to uphold. Health care ethics consultants are bioethicists who work in health care settings. They have been seeking guidance documents that speak to their special relationships/duties toward those they serve. By approving a Code of Ethics and Professional Responsibilities for Health Care Ethics Consultants, the American Society for Bioethics and Humanities (ASBH) has moved the professionalization debate forward in a significant way. This first code of ethics focuses on individuals who provide health care ethics consultation (HCEC) in clinical settings. The evolution of the code's development, implications for the field of HCEC and bioethics, and considerations for future directions are presented here.

Taking stock of the ethical foundations of international health research: pragmatic lessons from the IU-Moi Academic Research Ethics Partnership.

PubMed

Meslin, Eric M; Were, Edwin; Ayuku, David

2013-09-01

It is a sine qua non that research and health care provided in international settings raise profound ethical questions when different cultural and political values are implicated. Yet ironically, as international health research expands and as research on ethical issues in international health research broadens and deepens, we appear to have moved away from discussing the moral foundations of these activities. For international health research to thrive and lead to the kind of benefits it is capable of, it is helpful to occasionally revisit the foundational premises that justify the enterprise as a whole. We draw on the experience of the Indiana University-Moi University Academic Research Ethics Partnership, an innovative bioethics training program co-located in Indianapolis and Eldoret, Kenya to highlight the changing nature of ethical issues in international health research and the ongoing practical challenges.

Effects of a primordial magnetic field with log-normal distribution on the cosmic microwave background

NASA Astrophysics Data System (ADS)

Yamazaki, Dai G.; Ichiki, Kiyotomo; Takahashi, Keitaro

2011-12-01

We study the effect of primordial magnetic fields (PMFs) on the anisotropies of the cosmic microwave background (CMB). We assume the spectrum of PMFs is described by log-normal distribution which has a characteristic scale, rather than power-law spectrum. This scale is expected to reflect the generation mechanisms and our analysis is complementary to previous studies with power-law spectrum. We calculate power spectra of energy density and Lorentz force of the log-normal PMFs, and then calculate CMB temperature and polarization angular power spectra from scalar, vector, and tensor modes of perturbations generated from such PMFs. By comparing these spectra with WMAP7, QUaD, CBI, Boomerang, and ACBAR data sets, we find that the current CMB data set places the strongest constraint at k≃10-2.5Mpc-1 with the upper limit B≲3nG.

Application of modified extended method in CREAM for safety inspector in coal mines

NASA Astrophysics Data System (ADS)

Wang, Jinhe; Zhang, Xiaohong; Zeng, Jianchao

2018-01-01

Safety inspector often performs duties in circumstances contributes to the oc currence of human failures. Therefore, the paper aims at quantifying human failure pro bability (HFP) of safety inspector during the coal mine operation with cognitive reliabi lity and error analysis method (CREAM). Whereas, some shortcomings of this approa ch that lacking considering the applicability of the common performance condition (C PC), and the subjective of evaluating CPC level which weaken the accuracy of the qua ntitative prediction results. A modified extended method in CREAM which is able to a ddress these difficulties with a CPC framework table is proposed, and the proposed me thodology is demonstrated by the virtue of a coal-mine accident example. The results a re expected to be useful in predicting HFP of safety inspector and contribute to the enh ancement of coal mine safety.

Evaluation experimentale et theorique du comportement a la flexion de nouveaux poteaux en materiaux composites

NASA Astrophysics Data System (ADS)

Metiche, Slimane

La demande croissante en poteaux pour les differents reseaux d'electricite et de telecommunications a rendu necessaire l'utilisation de materiaux innovants, qui preservent l'environnement. La majorite des poteaux electriques existants au Canada ainsi qu'a travers le monde, sont fabriques a partir de materiaux traditionnels tel que le bois, le beton ou l'acier. Les motivations des industriels et des chercheurs a penser a d'autres solutions sont diverses, citons entre autre: La limitation en longueur des poteaux en bois ainsi que la vulnerabilite des poteaux fabriques en beton ou en acier aux agressions climatiques. Les nouveaux poteaux en materiaux composites se presentent comme de bons candidats a cet effet, cependant; leur comportement structural n'est pas connu et des etudes theoriques et experimentales approfondies sont necessaires avant leur mise en marche a grande echelle. Un programme de recherche intensif comportant plusieurs projets experimentaux, analytiques et numeriques est en cours a l'Universite de Sherbrooke afin d'evaluer le comportement a court et a long termes de ces nouveaux poteaux en Polymeres Renforces de Fibres (PRF). C'est dans ce contexte que s'inscrit la presente these, et notre recherche vise a evaluer le comportement a la flexion de nouveaux poteaux tubulaires coniques fabriques en materiaux composites par enroulement filamentaire et ce, a travers une etude theorique, ainsi qu'a travers une serie d'essais de flexion en "grandeur reelle" afin de comprendre le comportement structural de ces poteaux, d'optimiser la conception et de proposer une procedure de dimensionnement pour les utilisateurs. Les poteaux en Polymeres Renforces de Fibres (PRF) etudies dans cette these sont fabriques avec une resine epoxyde renforcee de fibres de verre type E. Chaque type poteaux est constitue principalement de trois zones ou les proprietes geometriques (epaisseur, diametre) et les proprietes mecaniques sont differentes d'une zone a l'autre. La difference

Reliability and Validity: A Sine Qua Non for Fair Assessment of Undergraduate Technical and Vocational Education Projects in Nigerian Universities

ERIC Educational Resources Information Center

John, A. C.

2015-01-01

The aim of the study was to examine the importance of reliability and validity as necessary foundation for fair assessment. The concepts of reliability, validity, fair assessment and their relationships were analysed. Qualities of fair assessment were discussed. A number of recommendations were made to make assessors be more cautious in award of…

Exploring synergistic interactions and catalysts in complex interventions: longitudinal, mixed methods case studies of an optimised multi-level suicide prevention intervention in four european countries (Ospi-Europe).

PubMed

Harris, Fiona M; Maxwell, Margaret; O'Connor, Rory; Coyne, James C; Arensman, Ella; Coffey, Claire; Koburger, Nicole; Gusmão, Ricardo; Costa, Susana; Székely, András; Cserhati, Zoltan; McDaid, David; van Audenhove, Chantal; Hegerl, Ulrich

2016-03-15

The Medical Research Council (MRC) Framework for complex interventions highlights the need to explore interactions between components of complex interventions, but this has not yet been fully explored within complex, non-pharmacological interventions. This paper draws on the process evaluation data of a suicide prevention programme implemented in four European countries to illustrate the synergistic interactions between intervention levels in a complex programme, and to present our method for exploring these. A realist evaluation approach informed the process evaluation, which drew on mixed methods, longitudinal case studies. Data collection consisted of 47 semi-structured interviews, 12 focus groups, one workshop, fieldnoted observations of six programme meetings and 20 questionnaires (delivered at six month intervals to each of the four intervention sites). Analysis drew on the framework approach, facilitated by the use of QSR NVivo (v10). Our qualitative approach to exploring synergistic interactions (QuaSIC) also developed a matrix of hypothesised synergies that were explored within one workshop and two waves of data collection. All four implementation countries provided examples of synergistic interactions that added value beyond the sum of individual intervention levels or components in isolation. For instance, the launch ceremony of the public health campaign (a level 3 intervention) in Ireland had an impact on the community-based professional training, increasing uptake and visibility of training for journalists in particular. In turn, this led to increased media reporting of OSPI activities (monitored as part of the public health campaign) and also led to wider dissemination of editorial guidelines for responsible reporting of suicidal acts. Analysis of the total process evaluation dataset also revealed the new phenomenon of the OSPI programme acting as a catalyst for externally generated (and funded) activity that shared the goals of suicide prevention

Filling in the gaps: Illuminating (a) Clearing mechanisms in transitional protoplanetary disks, and (b) Quantitative illiteracy among undergraduate science students

NASA Astrophysics Data System (ADS)

Follette, Katherine Brutlag

introduction to the literature and study motivation in Chapter 6. Chapter 7 describes the development and validation of the Quantitative Reasoning for College Science (QuaRCS) Assessment instrument. Chapter 8 briefly describes the next steps for Phase II of the QuaRCS study.

STS-81 Flight Day 7

NASA Technical Reports Server (NTRS)

1997-01-01

On this seventh first day of the STS-81 mission, the flight crew, Cmdr. Michael A. Baker, Pilot Brent W. Jett, Mission Specialists, John M. Grunsfeld, Marsha S. Ivins, Peter J.K. Wisoff, and John Blaha, and the cosmonauts of the Russian Space Station Mir continue to transfer hundreds of pounds of water, supplies, and logistical items to each other's spacecraft. More than 1,300 pounds of water have now been transferred from Atlantis to the Mir to resupply the Russian outpost, along with equipment that will be used by astronaut Jerry M. Linenger during his four-month research mission. A bioprocessing device and an experiment used to grow cartilage cells during astronaut John Blaha's four month stay on the Mir is also transferred to Atlantis for the trip back to Earth. Linenger spends most of the day collecting water samples from the Mir for analysis back on Earth and Blaha continues to exercise on a treadmill on the Mir to stay in shape for his return to Earth and a readaptation to gravity after four months of weightlessness.

Flight teams compare notes

NASA Image and Video Library

2013-11-13

NASA Operation IceBridge pilot Michael Anderson chats with Lt. Colonel Brent Keenan aboard a U.S. Air Force C-17 transport aircraft during a flight from Christchurch, New Zealand, to the U.S. Antarctic Program's McMurdo Station in Antarctica on Nov. 12, 2013. The C-17s that ferry people, equipment and supplies to Antarctica are operated by the U.S. Air Force's 62nd and 446th Airlift Wings based at Joint Base Lewis-McChord near Seattle, Wash. NASA's Operation IceBridge is an airborne science mission to study Earth's polar ice. In 2013, IceBridge is conducting its first field campaign directly from Antarctica. For more information about IceBridge, visit: www.nasa.gov/icebridge Credit: NASA/Goddard/Jefferson Beck NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

Current opinion on auricular reconstruction.

PubMed

Sivayoham, Eason; Woolford, Tim J

2012-08-01

To review the current practice in the field of auricular reconstruction and to highlight the recent advances reported in the medical literature. The majority of surgeons who perform auricular reconstruction continue to employ the well-established techniques developed by Brent and Nagata. Surgery takes between two and four stages, with the initial stage being construction of a framework of autogenous rib cartilage which is implanted into a subcutaneous pocket. Several modifications of these techniques have been reported. More recently, synthetic frameworks have been employed instead of autogenous rib cartilage. For this procedure, the implant is generally covered with a temporoparietal flap and a skin graft at the first stage of surgery. Tissue engineering is a rapidly developing field, and there have been several articles related to the field of auricular reconstruction. These show great potential to offer a solution to the challenge associated with construction of a viable autogenous cartilage framework, whilst avoiding donor-site morbidity. This article gives an overview of the current practice in the field of auricular reconstruction and summarizes the recent surgical developments and relevant tissue engineering research.

KSC-00pp1662

NASA Image and Video Library

2000-11-07

The International Space Station ground operations officially turn over the P6 Integrated Truss Structure to the NASA shuttle integration team in a ceremony in the Space Station Processing Facility. A symbolic key is presented to Brent Jett (at left), commander on mission STS-97, which is taking the P6 to the International Space Station. Next to him are (left to right) Bill Dowdell, mission manager; Mark Sorensen, outboard truss cargo element manager for Boeing; and John Elbon, Boeing ISS director of ground operations at KSC. Among the attendees at left watching the ceremony are other STS-97 crew members (in uniform, from left) Mission Specialists Joe Tanner and Carlos Noriega and Pilot Mike Bloomfield. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission involves two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at 10:05 p.m. EST

KSC00pp1662

NASA Image and Video Library

2000-11-07

The International Space Station ground operations officially turn over the P6 Integrated Truss Structure to the NASA shuttle integration team in a ceremony in the Space Station Processing Facility. A symbolic key is presented to Brent Jett (at left), commander on mission STS-97, which is taking the P6 to the International Space Station. Next to him are (left to right) Bill Dowdell, mission manager; Mark Sorensen, outboard truss cargo element manager for Boeing; and John Elbon, Boeing ISS director of ground operations at KSC. Among the attendees at left watching the ceremony are other STS-97 crew members (in uniform, from left) Mission Specialists Joe Tanner and Carlos Noriega and Pilot Mike Bloomfield. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission involves two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at 10:05 p.m. EST

KSC-00pp1661

NASA Image and Video Library

2000-11-07

Boeing workers officially turn over the P6 Integrated Truss Structure to the NASA shuttle integration team in a ceremony in the Space Station Processing Facility. A symbolic key will be presented to Brent Jett (at left), commander on mission STS-97, which is taking the P6 to the International Space Station. Next to Jett are (left to right) Bill Dowdell, mission manager; Mark Sorensen, outboard truss cargo element manager for Boeing; and John Elbon, Boeing ISS director of ground operations at KSC. Among the attendees at left watching the ceremony are other STS-97 crew members (in uniform, from left) Mission Specialists Joe Tanner and Carlos Noriega and Pilot Mike Bloomfield. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission involves two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at 10:05 p.m. EST

KSC-06pd2079

NASA Image and Video Library

2006-09-08

KENNEDY SPACE CENTER, FLA. - In the Operations and Checkout Building at NASA Kennedy Space Center, STS-115 Commander Brent Jett dons his launch and re-entry suit before heading to the launch pad. Jett is making his fourth shuttle flight on this mission to the International Space Station aboard Space Shuttle Atlantis. On its second attempt for launch, Atlantis is scheduled to lift off at 11:41 a.m. EDT today from Launch Pad 39B. During the STS-115 mission, Atlantis' astronauts will deliver and install the 17.5-ton, bus-sized P3/P4 integrated truss segment on the station. The girder-like truss includes a set of giant solar arrays, batteries and associated electronics and will provide one-fourth of the total power-generation capability for the completed station. This mission is the 116th space shuttle flight, the 27th flight for orbiter Atlantis, and the 19th U.S. flight to the ISS. STS-115 is scheduled to last 11 days with a planned landing at KSC. Photo credit: NASA/Kim Shiflett

STS-97 crew meets with the media at Launch Pad 39B

NASA Technical Reports Server (NTRS)

2000-01-01

From the slidewire landing zone at Launch Pad 39B, STS-97 Mission Specialist Joe Tanner (center, with microphone) speaks to the press about his extravehicular activity (EVA) during the mission. With him are the rest of the crew, Commander Brent Jett and Pilot Mike Bloomfield on the left and Mission Specialists Marc Garneau and Carlos Noriega on the right. The crew is at KSC to take part in Terminal Countdown Demonstration Test activities that include emergency egress training, familiarization with the payload, and a simulated launch countdown. Visible in the background are the solid rocket booster and external tank on Space Shuttle Endeavour. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:05 p.m. EST.

The STS-97 crew meets with the media at Launch Pad 39B

NASA Technical Reports Server (NTRS)

2000-01-01

From the slidewire landing zone at Launch Pad 39B, STS-97 Mission Specialist Joe Tanner (center, with microphone) speaks to the press about his extravehicular activity (EVA) during the mission. With him are the rest of the crew, Commander Brent Jett and Pilot Mike Bloomfield on the left and Mission Specialists Marc Garneau and Carlos Noriega on the right. The crew is at KSC to take part in Terminal Countdown Demonstration Test activities that include emergency egress training, familiarization with the payload, and a simulated launch countdown. Visible in the background are the solid rocket booster and external tank on Space Shuttle Endeavour. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:05 p.m. EST.

The STS-97 crew meets with the media at Launch Pad 39B

NASA Technical Reports Server (NTRS)

2000-01-01

The STS-97 crew poses for another photo after meeting with the media at the slidewire landing zone. They are, left to right, Commander Brent Jett, Pilot Mike Bloomfield and Mission Specialists Joe Tanner, Marc Garneau and Carlos Noriega. Garneau is with the Canadian Space Agency. The nets suspended behind them are a braking system catch net for the slidewire baskets that provide emergency exit from the orbiter and Fixed Service Structure. The crew is at KSC to take part in Terminal Countdown Demonstration Test activities that include emergency egress training, familiarization with the payload, and a simulated launch countdown. Visible in the background are the solid rocket booster and external tank on Space Shuttle Endeavour. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at 10:05 p.m. EST.

STS-97 crew meets with the media at Launch Pad 39B

NASA Technical Reports Server (NTRS)

2000-01-01

Standing in the slidewire landing zone at Launch Pad 39B, the STS-97 crew respond to questions from the media. Commander Brent Jett (on left, with microphone) introduces the rest of the crew (left to right) Pilot Mike Bloomfield and Mission Specialists Joe Tanner, Marc Garneau and Carlos Noriega. Garneau is with the Canadian Space Agency. The nets suspended behind them are a braking system catch net for the slidewire baskets that provide emergency exit from the orbiter and Fixed Service Structure. The crew is at KSC to take part in Terminal Countdown Demonstration Test activities that include emergency egress training, familiarization with the payload, and a simulated launch countdown. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:05 p.m. EST.

The STS-97 crew meets with the media at Launch Pad 39B

NASA Technical Reports Server (NTRS)

2000-01-01

Standing in the slidewire landing zone at Launch Pad 39B, the STS-97 crew respond to questions from the media. They are, left to right, Commander Brent Jett, Pilot Mike Bloomfield and Mission Specialists Joe Tanner, Marc Garneau and Carlos Noriega. Garneau is with the Canadian Space Agency. The nets suspended behind them are a braking system catch net for the slidewire baskets that provide emergency exit from the orbiter and Fixed Service Structure. The crew is at KSC to take part in Terminal Countdown Demonstration Test activities that include emergency egress training, familiarization with the payload, and a simulated launch countdown. Visible in the background are the solid rocket booster and external tank on Space Shuttle Endeavour. Mission STS-97is the sixth construction flight to the International Space Station. Its payload includes the P6 Integrated Truss Structure and a photovoltaic (PV) module, with giant solar arrays that will provide power to the Station. The mission includes two spacewalks to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:05 p.m. EST.

A qubit coupled with confined phonons: The interplay between true and fake decoherence

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pouthier, Vincent

2013-08-07

The decoherence of a qubit coupled with the phonons of a finite-size lattice is investigated. The confined phonons no longer behave as a reservoir. They remain sensitive to the qubit so that the origin of the decoherence is twofold. First, a qubit-phonon entanglement yields an incomplete true decoherence. Second, the qubit renormalizes the phonon frequency resulting in fake decoherence when a thermal average is performed. To account for the initial thermalization of the lattice, the qua- ntum Langevin theory is applied so that the phonons are viewed as an open system coupled with a thermal bath of harmonic oscillators. Consequently,more » it is shown that the finite lifetime of the phonons does not modify fake decoherence but strongly affects true decoherence. Depending on the values of the model parameters, the interplay between fake and true decoherence yields a very rich dynamics with various regimes.« less

A fireball analysis from Spanish meteor observations

NASA Astrophysics Data System (ADS)

Benítez Sánchez, O.; Ocaña González, F.

2004-03-01

Naked eye meteor records from Spain are used for an analysis of 3240 fireballs reported by members of the Sociedad de Observadores de Meteoros Y Cometas de España (SOMYCE) and by casual eye-witnesses from 1982 to 2000. This analysis concerns various areas, such as statistical studies of the colours and the frequency of fireballs in annual meteor showers. Annual and diurnal variations are also discussed. We describe the population index r for magnitudes brighter than m=-2 for ORI, VIR, AQU, TAU, CAP, QUA, GEM, LYR, LEO, KCG, PER and sporadic fireballs. The typical population index is always in the range ≃ 1.2 to 1.9, except for Perseids and Geminids. An investigation of visual fireballs radiants was attempted with the Radiant software. The sample of fireballs (282 fireballs with the path reported) only shows evidence for the Perseids and Leonids.

Effects of competition on video-task performance in monkeys (Macaca mulatta)

NASA Technical Reports Server (NTRS)

Washburn, David A.; Hopkins, William D.; Rumbaugh, Duane M.

1990-01-01

The effects of competition on performance of a video-formatted task were examined in a series of experiments. Two rhesus monkeys (Macaca mulatta) were trained to manipulate a joystick to shoot at moving targets on a computer screen. The task was made competitive by requiring both animals to shoot at the same target and by rewarding only the animal that hit the target first each trial. The competitive task produced a significant and robust speed-accuracy trade-off in performance. The monkeys hit the target in significantly less time on contested than on uncontested trials. However, they required significantly more shots to hit the target on contested trials in relation to uncontested trials. This effect was unchanged when various schedules of reinforcement were introduced in the uncontested trials. This supports the influence of competition qua competition on performance, a point further bolstered by other findings of behavioral contrast presented here.

Post-dural puncture headache

PubMed Central

Ghaleb, Ahmed; Khorasani, Arjang; Mangar, Devanand

2012-01-01

Since August Bier reported the first case in 1898, post-dural puncture headache (PDPH) has been a problem for patients following dural puncture. Clinical and laboratory research over the last 30 years has shown that use of smaller-gauge needles, particularly of the pencil-point design, are associated with a lower risk of PDPH than traditional cutting point needle tips (Quincke-point needle). A careful history can rule out other causes of headache. A postural component of headache is the sine qua non of PDPH. In high-risk patients < 50 years, post-partum, in the event a large-gauge needle puncture is initiated, an epidural blood patch should be performed within 24–48 hours of dural puncture. The optimum volume of blood has been shown to be 12–20 mL for adult patients. Complications caused by autologous epidural blood patching (AEBP) are rare. PMID:22287846

Planetary spectra for anisotropic scattering

NASA Technical Reports Server (NTRS)

Chamberlain, J. W.

1976-01-01

Some effects on planetary spectra that would be produced by departures from isotropic scattering are examined. The phase function is the simplest departure to handle analytically and the only phase function, other than the isotropic one, that can be incorporated into a Chandrasekhar first approximation. This approach has the advantage of illustrating effects resulting from anisotropies while retaining the simplicity that yields analytic solutions. The curve of growth is the sine qua non of planetary spectroscopy. The discussion emphasizes the difficulties and importance of ascertaining curves of growth as functions of observing geometry. A plea is made to observers to analyze their empirical curves of growth, whenever it seems feasible, in terms of coefficients of which are the leading terms in radiative-transfer analysis. An algebraic solution to the two sets of anisotropic H functions is developed which gives emergent intensities accurate to 0.3%.

Setting the standards for signal transduction research.

PubMed

Saez-Rodriguez, Julio; Alexopoulos, Leonidas G; Stolovitzky, Gustavo

2011-02-15

Major advances in high-throughput technology platforms, coupled with increasingly sophisticated computational methods for systematic data analysis, have provided scientists with tools to better understand the complexity of signaling networks. In this era of massive and diverse data collection, standardization efforts that streamline data gathering, analysis, storage, and sharing are becoming a necessity. Here, we give an overview of current technologies to study signal transduction. We argue that along with the opportunities the new technologies open, their heterogeneous nature poses critical challenges for data handling that are further increased when data are to be integrated in mathematical models. Efficient standardization through markup languages and data annotation is a sine qua non condition for a systems-level analysis of signaling processes. It remains to be seen the extent to which and the speed at which the emerging standardization efforts will be embraced by the signaling community.

Treatment of depression in older adults beyond fluoxetine

PubMed Central

Wagner, Gabriela Arantes

2015-01-01

This review aimed to discuss the importance of the comprehensive treatment of depression among older adults in Brazil. The abuse of selective serotonin reuptake inhibitors, including fluoxetine hydrochloride, as antidepressants has been considered a serious public health problem, particularly among older adults. Despite the consensus on the need for a comprehensive treatment of depression in this population, Brazil is still unprepared. The interface between pharmacotherapy and psychotherapy is limited due to the lack of healthcare services, specialized professionals, and effective healthcare planning. Fluoxetine has been used among older adults as an all-purpose drug for the treatment of depressive disorders because of psychosocial adversities, lack of social support, and limited access to adequate healthcare services for the treatment of this disorder. Preparing health professionals is a sine qua non for the reversal of the age pyramid, but this is not happening yet. PMID:25830872

Initial Performance Assessment of CALIOP

NASA Technical Reports Server (NTRS)

Winker, David; Hunt, Bill; McGill, Matthew

2007-01-01

The Cloud-Aerosol Lidar with Orthogonal Polarization (CALIOP, pronounced the same as "calliope") is a spaceborne two-wavelength polarizatio n lidar that has been acquiring global data since June 2006. CALIOP p rovides high resolution vertical profiles of clouds and aerosols, and has been designed with a very large linear dynamic range to encompas s the full range of signal returns from aerosols and clouds. CALIOP is the primary instrument carried by the Cloud-Aerosol Lidar and Infrar ed Pathfinder Satellite Observations (CALIPSO) satellite, which was l aunched on April, 28 2006. CALIPSO was developed within the framework of a collaboration between NASA and the French space agency, CNES. I nitial data analysis and validation intercomparisons indicate the qua lity of data from CALIOP meets or exceeds expectations. This paper presents a description of the CALIPSO mission, the CALIOP instrument, an d an initial assessment of on-orbit measurement performance.

The Biotechnology of Ugba, a Nigerian Traditional Fermented Food Condiment

PubMed Central

Olasupo, Nurudeen A.; Okorie, Chimezie P.; Oguntoyinbo, Folarin A.

2016-01-01

Legumes and oil bean seeds used for the production of condiments in Africa are inedible in their natural state; they contain some anti-nutritional factors especially undigestible oligosaccharides and phytate. Fermentation impact desirable changes by reducing anti-nutritional factors and increasing digestibility. Ugba is an alkaline fermented African oil bean cotyledon (Pentaclethra macrophylla) produced by the Ibos and other ethnic groups in southern Nigeria. Seen as a family business in many homes, its preparation is in accordance with handed-down tradition from previous generations and serves as a cheap source of plant protein. Its consumption as a native salad is made possible by fermentation of the cotyledon for 2–5 days, but could also serve as a soup flavoring agent when fermentation last for 6–10 days. The fermentation process involved is usually natural with an attendant issue of product safety, quality and inconsistency. The production of this condiment is on a small scale and the equipment used are very rudimentary, devoid of good manufacturing procedures that call to question the issue of microbial safety. This paper therefore reviews the production process and the spectrum of microbial composition involved during fermentation. In addition, potential spoilage agents, nutritional and biochemical changes during production are examined. Furthermore, information that can support development of starter cultures for controlled fermentation process in order to guarantee microbiological safety, quality and improved shelf life are also discussed. PMID:27540371

Use of a 12 months' self-referral reminder to facilitate uptake of bowel scope (flexible sigmoidoscopy) screening in previous non-responders: a London-based feasibility study

PubMed Central

Kerrison, Robert S; McGregor, Lesley M; Marshall, Sarah; Isitt, John; Counsell, Nicholas; Wardle, Jane; von Wagner, Christian

2016-01-01

Background: In March 2013, NHS England extended its national Bowel Cancer Screening Programme to include ‘one-off' Flexible Sigmoidoscopy screening (NHS Bowel Scope Screening, BSS) for men and women aged 55. With less than one in two people currently taking up the screening test offer, there is a strong public health mandate to develop system-friendly interventions to increase uptake while the programme is rolling out. This study aimed to assess the feasibility of sending a reminder to previous BSS non-responders, 12 months after the initial invitation, with consideration for its potential impact on uptake. Method: This study was conducted in the ethnically diverse London Boroughs of Brent and Harrow, where uptake is below the national average. Between September and November 2014, 160 previous non-responders were randomly selected to receive a reminder of the opportunity to self-refer 12 months after their initial invitation. The reminder included instructions on how to book an appointment, and provided options for the time and day of the appointment and the gender of the endoscopist performing the test. To address barriers to screening, the reminder was sent with a brief locally tailored information leaflet designed specifically for this study. Participants not responding within 4 weeks were sent a follow-up reminder, after which there was no further intervention. Self-referral rates were measured 8 weeks after the delivery of the follow-up reminder and accepted as final. Results: Of the 155 participants who received the 12 months' reminder (returned to sender, n=5), 30 (19.4%) self-referred for an appointment, of which 24 (15.5%) attended and were successfully screened. Attendance rates differed by gender, with significantly more women attending an appointment than men (20.7% vs 8.8%, respectively; OR=2.73, 95% CI=1.02–7.35, P=0.05), but not by area (Brent vs Harrow) or area-level deprivation. Of the 30 people who self-referred for an appointment, 27 (90

What is CAR doing in the middle of the adult neurogenic road?

PubMed Central

Junyent, Felix; Coré, Nathalie; Cremer, Harold

2017-01-01

ABSTRACT The molecular and cellular basis of adult neurogenesis has attracted considerable attention for fundamental and clinical applications because neural stem cells and newborn neurons may, one day, be harnessed to replace neurons and allow cognitive improvement in the diseased brain. In rodents, neural progenitors are located in the dentate gyrus and the sub/periventricular zone. In the dentate gyrus the generation of newborn neurons is associated with plasticity, including regulation of memory. The role of subventricular zone neural precursors that migrate to the olfactory bulb is less characterized. Identifying factors that impact neural stem cell proliferation, migration and differentiation is therefore sine qua non before we can harness their potential. Here, we expand upon our recent results showing that CAR, the coxsackievirus and adenovirus receptor, is among the developing list of key players when it comes to the complex process of integrating newborn neurons into existing circuits in the mature brain. PMID:28516108

The Emergence of Single Neurons in Clinical Neurology

PubMed Central

Cash, Sydney S.; Hochberg, Leigh R.

2015-01-01

Summary Single neuron actions and interactions are the sine qua non of brain function, and nearly all diseases and injuries of the central nervous system trace their clinical sequelae to neuronal dysfunction or failure. Remarkably, discussion of neuronal activity is largely absent in clinical neuroscience. Advances in neurotechnology and computational capabilities, accompanied by shifts in theoretical frameworks, have led to renewed interest in the information represented by single neurons. Using direct interfaces with the nervous system, millisecond-scale information will soon be extracted from single neurons in clinical environments, supporting personalized treatment of neurologic and psychiatric disease. In this review we focus on single neuronal activity in restoring communication and motor control in patients suffering from devastating neurological injuries. We also explore the single neuron's role in epilepsy and movement disorders, surgical anesthesia, and in cognitive processes disrupted in neurodegenerative and neuropsychiatric disease. Finally, we speculate on how technological advances will revolutionize neurotherapeutics. PMID:25856488

The emergence of single neurons in clinical neurology.

PubMed

Cash, Sydney S; Hochberg, Leigh R

2015-04-08

Single neuron actions and interactions are the sine qua non of brain function, and nearly all diseases and injuries of the CNS trace their clinical sequelae to neuronal dysfunction or failure. Remarkably, discussion of neuronal activity is largely absent in clinical neuroscience. Advances in neurotechnology and computational capabilities, accompanied by shifts in theoretical frameworks, have led to renewed interest in the information represented by single neurons. Using direct interfaces with the nervous system, millisecond-scale information will soon be extracted from single neurons in clinical environments, supporting personalized treatment of neurologic and psychiatric disease. In this Perspective, we focus on single-neuronal activity in restoring communication and motor control in patients suffering from devastating neurological injuries. We also explore the single neuron's role in epilepsy and movement disorders, surgical anesthesia, and in cognitive processes disrupted in neurodegenerative and neuropsychiatric disease. Finally, we speculate on how technological advances will revolutionize neurotherapeutics. Copyright © 2015 Elsevier Inc. All rights reserved.

Expansion of the gateway multisite recombination cloning toolkit.

PubMed

Shearin, Harold K; Dvarishkis, Alisa R; Kozeluh, Craig D; Stowers, R Steven

2013-01-01

Precise manipulation of transgene expression in genetic model organisms has led to advances in understanding fundamental mechanisms of development, physiology, and genetic disease. Transgene construction is, however, a precondition of transgene expression, and often limits the rate of experimental progress. Here we report an expansion of the modular Gateway MultiSite recombination-cloning platform for high efficiency transgene assembly. The expansion includes two additional destination vectors and entry clones for the LexA binary transcription system, among others. These new tools enhance the expression levels possible with Gateway MultiSite generated transgenes and make possible the generation of LexA drivers and reporters with Gateway MultiSite cloning. In vivo data from transgenic Drosophila functionally validating each novel component are presented and include neuronal LexA drivers, LexAop2 red and green fluorescent synaptic vesicle reporters, TDC2 and TRH LexA, GAL4, and QF drivers, and LexAop2, UAS, and QUAS channelrhodopsin2 T159C reporters.

Expansion of the Gateway MultiSite Recombination Cloning Toolkit

PubMed Central

Shearin, Harold K.; Dvarishkis, Alisa R.; Kozeluh, Craig D.; Stowers, R. Steven

2013-01-01

Precise manipulation of transgene expression in genetic model organisms has led to advances in understanding fundamental mechanisms of development, physiology, and genetic disease. Transgene construction is, however, a precondition of transgene expression, and often limits the rate of experimental progress. Here we report an expansion of the modular Gateway MultiSite recombination-cloning platform for high efficiency transgene assembly. The expansion includes two additional destination vectors and entry clones for the LexA binary transcription system, among others. These new tools enhance the expression levels possible with Gateway MultiSite generated transgenes and make possible the generation of LexA drivers and reporters with Gateway MultiSite cloning. In vivo data from transgenic Drosophila functionally validating each novel component are presented and include neuronal LexA drivers, LexAop2 red and green fluorescent synaptic vesicle reporters, TDC2 and TRH LexA, GAL4, and QF drivers, and LexAop2, UAS, and QUAS channelrhodopsin2 T159C reporters. PMID:24204935

Effects of nitrogen seeding on core ion thermal transport in JET ILW L-mode plasmas

NASA Astrophysics Data System (ADS)

Bonanomi, N.; Mantica, P.; Citrin, J.; Giroud, C.; Lerche, E.; Sozzi, C.; Taylor, D.; Tsalas, M.; Van Eester, D.; contributors, JET

2018-02-01

A set of experiments was carried out in JET ILW (Joint European Torus with ITER-Like Wall) L-mode plasmas in order to study the effects of light impurities on core ion thermal transport. N was puffed into some discharges and its profile was measured by active Charge Exchange diagnostics, while ICRH power was deposited on- and off-axis in ({\\hspace{0pt}}3He)-D minority scheme in order to have a scan of local heat flux at constant total power with and without N injection. Experimentally, the ion temperature profiles are more peaked for similar heat fluxes when N is injected in the plasma. Gyro-kinetic simulations using the GENE code indicate that a stabilization of Ion Temperature Gradient driven turbulent transport due to main ion dilution and to changes in Te/Ti and s/q is responsible of the enhanced peaking. The quasi-linear models TGLF and QuaLiKiz are tested against the experimental and the gyro-kinetic results.

Synthetic biology between technoscience and thing knowledge.

PubMed

Gelfert, Axel

2013-06-01

Synthetic biology presents a challenge to traditional accounts of biology: Whereas traditional biology emphasizes the evolvability, variability, and heterogeneity of living organisms, synthetic biology envisions a future of homogeneous, humanly engineered biological systems that may be combined in modular fashion. The present paper approaches this challenge from the perspective of the epistemology of technoscience. In particular, it is argued that synthetic-biological artifacts lend themselves to an analysis in terms of what has been called 'thing knowledge'. As such, they should neither be regarded as the simple outcome of applying theoretical knowledge and engineering principles to specific technological problems, nor should they be treated as mere sources of new evidence in the general pursuit of scientific understanding. Instead, synthetic-biological artifacts should be viewed as partly autonomous research objects which, qua their material-biological constitution, embody knowledge about the natural world-knowledge that, in turn, can be accessed via continuous experimental interrogation. Copyright © 2013 Elsevier Ltd. All rights reserved.

Memory as persona non grata in the work of Eugène Minkowski: a historical approach.

PubMed

Vaz, João M

2016-09-01

Memory is both ubiquitous and persona non grata in the work of Eugène Minkowski. Despite the relevance of memory in the works of those who influenced him, in particular Bergson, Minkowski nonetheless repeatedly overlooked its importance in his writings. To the reader of his work this fact is as much evident as unaccounted for - both by prior research and by Minkowski himself. I shall try to prove that this disregard for memory was conditio sine qua non of Minkowski's first synthesis of Bleuler and Bergson in a 1921 article, which resulted in his famous concept of loss of vital contact with reality and which he equated with schizophrenia. Moreover, this historical approach will, on the one hand, explain the fragmentary use made by Minkowski of the philosophy of Bergson and, on the other, shed light on central aspects of his Le temps vécu of 1933 that an exclusively philosophical analysis cannot reveal. © The Author(s) 2016.

Postdural Puncture Headache

PubMed Central

Ghaleb, Ahmed

2010-01-01

Postdural puncture headache (PDPH) has been a problem for patients, following dural puncture, since August Bier reported the first case in 1898. His paper discussed the pathophysiology of low-pressure headache resulting from leakage of cerebrospinal fluid (CSF) from the subarachnoid to the epidural space. Clinical and laboratory research over the last 30 years has shown that use of small-gauge needles, particularly of the pencil-point design, is associated with a lower risk of PDPH than traditional cutting point needle tips (Quincke-point needle). A careful history can rule out other causes of headache. A postural component of headache is the sine qua non of PDPH. In high-risk patients , for example, age < 50 years, postpartum, large-gauge needle puncture, epidural blood patch should be performed within 24–48 h of dural puncture. The optimum volume of blood has been shown to be 12–20 mL for adult patients. Complications of AEBP are rare. PMID:20814596

All-Optical Electrophysiology for Disease Modeling and Pharmacological Characterization of Neurons.

PubMed

Werley, Christopher A; Brookings, Ted; Upadhyay, Hansini; Williams, Luis A; McManus, Owen B; Dempsey, Graham T

2017-09-11

A key challenge for establishing a phenotypic screen for neuronal excitability is measurement of membrane potential changes with high throughput and accuracy. Most approaches for probing excitability rely on low-throughput, invasive methods or lack cell-specific information. These limitations stimulated the development of novel strategies for characterizing the electrical properties of cultured neurons. Among these was the development of optogenetic technologies (Optopatch) that allow for stimulation and recording of membrane voltage signals from cultured neurons with single-cell sensitivity and millisecond temporal resolution. Neuronal activity is elicited using blue light activation of the channelrhodopsin variant 'CheRiff'. Action potentials and synaptic signals are measured with 'QuasAr', a rapid and sensitive voltage-indicating protein with near-infrared fluorescence that scales proportionately with transmembrane potential. This integrated technology of optical stimulation and recording of electrical signals enables investigation of neuronal electrical function with unprecedented scale and precision. © 2017 by John Wiley & Sons, Inc. Copyright © 2017 John Wiley & Sons, Inc.

Beyond Social Skills: Supporting Peer Relationships and Friendships for School-Aged Children with Autism Spectrum Disorder.

PubMed

Rodda, Amy; Estes, Annette

2018-04-01

Social impairments are the sine qua non of autism spectrum disorder (ASD). However, children with ASD are capable of forming reciprocal friendships and many people with ASD have a strong desire for friends. Developing and maintaining friendships is associated with many important outcomes, including improved quality of life, mental health, and academic achievement. Children with ASD often attend groups to improve social skills, but strategies for building and maintaining friendships are not consistently addressed or measured following intervention. In this article, our objective is to build an understanding of peer relationships and friendships in school-aged children with ASD and how to best support them. In this article, we describe characteristics of peer relationships and friendships for children with ASD. We discuss current research findings on intervention to improve social skills, peer relationships, and friendships in school-aged children with ASD. Finally, we give suggestions for clinical practice and future research. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Partnership in research: a tandem of opportunities and constraints.

PubMed

Ducharme, Francine

2003-01-01

Partnership is a term that is occurring more and more frequently in the research lexicon, an approach that is gradually becoming a sine qua non in the field of health and healthcare research in Canada. The purpose of this article is to share thoughts and experiences regarding research carried out in partnership. The relevance and necessity of partnerships in strategic health research will be examined, and the contribution of partnerships to the development and "re-centring" of intra- and interdisciplinary knowledge and knowledge transfer will be discussed. Based on the nursing and related-fields literature, the key elements of partnership, and the advantages and disadvantages of this strategy to pursuing research projects will be presented. An important issue in a professional discipline such as nursing will be discussed, i.e. the intra-disciplinary partnership between researchers and clinicians. Strategies that could enhance this particular type of partnership and avenues for catalyzing the synergy that must perforce develop, over the coming years, will be proposed.

[Quality management and safety culture in medicine: context and concepts].

PubMed

Wischet, Werner; Eitzinger, Claudia

2009-01-01

The publication of the IOM report "To err is human: building a safer health system" in 1999 put spotlight on the primacy of the principle of primum non nocere and made patient safety a central topic of quality management. A key conclusion of the report was the need for a well-developed safety culture. While concepts of quality management have evolved along the lines of ISO and Total Quality Management over the last decades patient safety still has not got the same amount of attention (PubMed). Evidence from other safety-critical areas but also from the field of medicine itself suggests that an efficient culture of safety is a conditio sine qua non for the sustainable improvement of patient safety. Considering these arguments the present paper aims at emphasizing the importance of an efficient culture of safety for patient safety and quality management in healthcare. In addition, key instruments of safety culture as well as their limitations will be presented.

A Cross-Cultural Multi-agent Model of Opportunism in Trade

NASA Astrophysics Data System (ADS)

Hofstede, Gert Jan; Jonker, Catholijn M.; Verwaart, Tim

According to transaction cost economics, contracts are always incomplete and offer opportunities to defect. Some level of trust is a sine qua non for trade. If the seller is better informed about product quality than the buyer, the buyer has to rely on information the seller provides or has to check the information by testing the product or tracing the supply chain processes, thus incurring extra transaction cost. An opportunistic seller who assumes the buyer to trust, may deliver a lower quality product than agreed upon. In human decisions to deceive and to show trust or distrust, issues like mutual expectations, shame, self-esteem, personality, and reputation are involved. These factors depend in part on traders' cultural background. This paper proposes an agent model of deceit and trust and describes a multi-agent simulation where trading agents are differentiated according to Hofstede's dimensions of national culture. Simulations of USA and Dutch trading situations are compared.

The responsibilities of engineers.

PubMed

Smith, Justin; Gardoni, Paolo; Murphy, Colleen

2014-06-01

Knowledge of the responsibilities of engineers is the foundation for answering ethical questions about the work of engineers. This paper defines the responsibilities of engineers by considering what constitutes the nature of engineering as a particular form of activity. Specifically, this paper focuses on the ethical responsibilities of engineers qua engineers. Such responsibilities refer to the duties acquired in virtue of being a member of a group. We examine the practice of engineering, drawing on the idea of practices developed by philosopher Alasdair MacIntyre, and show how the idea of a practice is important for identifying and justifying the responsibilities of engineers. To demonstrate the contribution that knowledge of the responsibilities of engineers makes to engineering ethics, a case study from structural engineering is discussed. The discussion of the failure of the Sleipner A Platform off the coast of Norway in 1991 demonstrates how the responsibilities of engineers can be derived from knowledge of the nature of engineering and its context.

Cartesian critters can't remember.

PubMed

Curry, Devin Sanchez

2018-06-01

Descartes held the following view of declarative memory: to remember is to reconstruct an idea that you intellectually recognize as a reconstruction. Descartes countenanced two overarching varieties of declarative memory. To have an intellectual memory is to intellectually reconstruct a universal idea that you recognize as a reconstruction, and to have a sensory memory is to neurophysiologically reconstruct a particular idea that you recognize as a reconstruction. Sensory remembering is thus a capacity of neither ghosts nor machines, but only of human beings qua mind-body unions. This interpretation unifies Descartes's various remarks (and conspicuous silences) about remembering, from the 1628 Rules for the Direction of the Mind through the suppressed-in-1633 Treatise of Man to the 1649 Passions of the Soul. It also rebuts a prevailing thesis in the current secondary literature-that Cartesian critters can remember-while incorporating the textual evidence for that thesis-Descartes's detailed descriptions of the corporeal mechanisms that construct sensory memories. Copyright © 2018 Elsevier Ltd. All rights reserved.

High-Frequency Measurements of Methane Ebullition Over a Growing Season at a Temperate Peatland Site

NASA Technical Reports Server (NTRS)

Goodrich, Jordan P.; Varner, Ruth K.; Frolking, Steve; Duncan, Bryan N.; Crill, Patrick M.

2011-01-01

Bubbles can contribute a significant fraction of methane emissions fr om wetlands; however the range of reported fractions is very large an d accurate characterization of this pathway has proven difficult. Her e we show that continuous automated flux chambers combined with an in tegrated cavity output spectroscopy (ICOS) instrument allow us to qua ntify both CH4 ebullition rate and magnitude. For a temperate poor f en in 2009, ebullition rate varied on hourly to seasonal time scales. A diel pattern in ebullition was identified with peak release occurr ing between 20:00 and 06:00 local time, though steady fluxes (i.e., t hose with a linear increase in chamber headspace CH4 concentration) d id not exhibit diel variability. Seasonal mean ebullition rates peake d at 843.5 +/- 384.2 events m(exp -2)/d during the summer, with a me an magnitude of 0.19 mg CH4 released in each event.

Human-Centered Automation: The View from Earth Versus the View from Mars

NASA Technical Reports Server (NTRS)

Massimino, Michael J.; Smith, Philip J.; Stilwell, Donald J.; Mitchell, Christine M.; Thurman, David A.; Malin, Jane T.; Jones, Patricia M.

1999-01-01

This panel addresses the topic of human-centered automation in, however, a very different context-manned missions to deep space in which predominantly autonomous systems must control the crew's life-support systems most of the time. The Mars spacecraft and its inhabitants are totally dependent on the proper operation of thousands of control loops and pieces of equipment to maintain the delicate, unbuffered homeostasis of their remote existence. Mission success hangs on a thread that depends on a successful partnership, or symbiosis. between crew and machines, which exceeds anything ever required of ground systems. The need for a new approach to human-centered automation is not a "frill" in future Mars mission, but rather a sine qua non of survival. Thus the issue is design: Can we design systems intended to operate in a predominantly autonomous mode. without a human backup, that are sufficiently safe such that human travel into deep space is possible?