Sample records for quadrant anode image

  1. Quadrant anode image sensor

    NASA Technical Reports Server (NTRS)

    Lampton, M.; Malina, R. F.

    1976-01-01

    A position-sensitive event-counting electronic readout system for microchannel plates (MCPs) is described that offers the advantages of high spatial resolution and fast time resolution. The technique relies upon a four-quadrant electron-collecting anode located behind the output face of the microchannel plate, so that the electron cloud from each detected event is partly intercepted by each of the four quadrants. The relative amounts of charge collected by each quadrant depend on event position, permitting each event to be localized with two ratio circuits. A prototype quadrant anode system for ion, electron, and extreme ultraviolet imaging is described. The spatial resolution achieved, about 10 microns, allows individual MCP channels to be distinguished.

  2. Reborn quadrant anode image sensor

    NASA Astrophysics Data System (ADS)

    Prokazov, Yury; Turbin, Evgeny; Vitali, Marco; Herzog, Andreas; Michaelis, Bernd; Zuschratter, Werner; Kemnitz, Klaus

    2009-06-01

    We describe a position sensitive photon counting microchannel plate based detector with an improved quadrant anode (QA) readout system. The technique relies on a combination of the four planar elements pattern and an additional fifth electrode. The charge cloud induced by single particle detection is split between the electrodes. The measured charge values uniquely define the position of the initial event. QA has been first published in 1976 by Lampton and Malina. This anode configuration was undeservedly forgotten and its potential has been hardly underestimated. The presented approach extends the operating spatial range to the whole sensitive area of the microchannel plate surface and demonstrates good linearity over the field of view. Therefore, the novel image sensor results in spatial resolution better then 50 μm and count rates up to one million events per second.

  3. Validation of an improved abnormality insertion method for medical image perception investigations

    NASA Astrophysics Data System (ADS)

    Madsen, Mark T.; Durst, Gregory R.; Caldwell, Robert T.; Schartz, Kevin M.; Thompson, Brad H.; Berbaum, Kevin S.

    2009-02-01

    The ability to insert abnormalities in clinical tomographic images makes image perception studies with medical images practical. We describe a new insertion technique and its experimental validation that uses complementary image masks to select an abnormality from a library and place it at a desired location. The method was validated using a 4-alternative forced-choice experiment. For each case, four quadrants were simultaneously displayed consisting of 5 consecutive frames of a chest CT with a pulmonary nodule. One quadrant was unaltered, while the other 3 had the nodule from the unaltered quadrant artificially inserted. 26 different sets were generated and repeated with order scrambling for a total of 52 cases. The cases were viewed by radiology staff and residents who ranked each quadrant by realistic appearance. On average, the observers were able to correctly identify the unaltered quadrant in 42% of cases, and identify the unaltered quadrant both times it appeared in 25% of cases. Consensus, defined by a majority of readers, correctly identified the unaltered quadrant in only 29% of 52 cases. For repeats, the consensus observer successfully identified the unaltered quadrant only once. We conclude that the insertion method can be used to reliably place abnormalities in perception experiments.

  4. Accuracy and Reliability of Eye-Based vs Quadrant-Based Diagnosis of Plus Disease in Retinopathy of Prematurity.

    PubMed

    Kim, Sang Jin; Campbell, J Peter; Kalpathy-Cramer, Jayashree; Ostmo, Susan; Jonas, Karyn E; Choi, Dongseok; Chan, R V Paul; Chiang, Michael F

    2018-06-01

    Presence of plus disease in retinopathy of prematurity is the most critical element in identifying treatment-requiring disease. However, there is significant variability in plus disease diagnosis. In particular, plus disease has been defined as 2 or more quadrants of vascular abnormality, and it is not clear whether it is more reliably and accurately diagnosed by eye-based assessment of overall retinal appearance or by quadrant-based assessment combining grades of 4 individual quadrants. To compare eye-based vs quadrant-based diagnosis of plus disease and to provide insight for ophthalmologists about the diagnostic process. In this multicenter cohort study, we developed a database of 197 wide-angle retinal images from 141 preterm infants from neonatal intensive care units at 9 academic institutions (enrolled from July 2011 to December 2016). Each image was assigned a reference standard diagnosis based on consensus image-based and clinical diagnosis. Data analysis was performed from February 2017 to September 2017. Six graders independently diagnosed each of the 4 quadrants (cropped images) of the 197 eyes (quadrant-based diagnosis) as well as the entire image (eye-based diagnosis). Images were displayed individually, in random order. Quadrant-based diagnosis of plus disease was made when 2 or more quadrants were diagnosed as indicating plus disease by combining grades of individual quadrants post hoc. Intragrader and intergrader reliability (absolute agreement and κ statistic) and accuracy compared with the reference standard diagnosis. Of the 141 included preterm infants, 65 (46.1%) were female and 116 (82.3%) white, and the mean (SD) gestational age was 27.0 (2.6) weeks. There was variable agreement between eye-based and quadrant-based diagnosis among the 6 graders (Cohen κ range, 0.32-0.75). Four graders showed underdiagnosis of plus disease with quadrant-based diagnosis compared with eye-based diagnosis (by McNemar test). Intergrader agreement of quadrant-based diagnosis was lower than that of eye-based diagnosis (Fleiss κ, 0.75 [95% CI, 0.71-0.78] vs 0.55 [95% CI, 0.51-0.59]). The accuracy of eye-based diagnosis compared with the reference standard diagnosis was substantial to near-perfect, whereas that of quadrant-based plus disease diagnosis was only moderate to substantial for each grader. Graders had lower reliability and accuracy using quadrant-based diagnosis combining grades of individual quadrants than with eye-based diagnosis, suggesting that eye-based diagnosis has advantages over quadrant-based diagnosis. This has implications for more precise definitions of plus disease regarding the criterion of 2 or more quadrants, clinical care, computer-based image analysis, and education for all ophthalmologists who manage retinopathy of prematurity.

  5. 3D MRI for Quantitative Analysis of Quadrant Percent Breast Density: Correlation with Quadrant Location of Breast Cancer.

    PubMed

    Chen, Jeon-Hor; Liao, Fuyi; Zhang, Yang; Li, Yifan; Chang, Chia-Ju; Chou, Chen-Pin; Yang, Tsung-Lung; Su, Min-Ying

    2017-07-01

    Breast cancer occurs more frequently in the upper outer (UO) quadrant, but whether this higher cancer incidence is related to the greater amount of dense tissue is not known. Magnetic resonance imaging acquires three-dimensional volumetric images and is the most suitable among all breast imaging modalities for regional quantification of density. This study applied a magnetic resonance imaging-based method to measure quadrant percent density (QPD), and evaluated its association with the quadrant location of the developed breast cancer. A total of 126 cases with pathologically confirmed breast cancer were reviewed. Only women who had unilateral breast cancer located in a clear quadrant were selected for analysis. A total of 84 women, including 47 Asian women and 37 western women, were included. An established computer-aided method was used to segment the diseased breast and the contralateral normal breast, and to separate the dense and fatty tissues. Then, a breast was further separated into four quadrants using the nipple and the centroid as anatomic landmarks. The tumor was segmented using a computer-aided method to determine its quadrant location. The distribution of cancer quadrant location, the quadrant with the highest QPD, and the proportion of cancers occurring in the highest QPD were analyzed. The highest incidence of cancer occurred in the UO quadrant (36 out of 84, 42.9%). The highest QPD was also noted most frequently in the UO quadrant (31 out of 84, 36.9%). When correlating the highest QPD with the quadrant location of breast cancer, only 17 women out of 84 (20.2%) had breast cancer occurring in the quadrant with the highest QPD. The results showed that the development of breast cancer in a specific quadrant could not be explained by the density in that quadrant, and further studies are needed to find the biological reasons accounting for the higher breast cancer incidence in the UO quadrant. Copyright © 2017 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.

  6. Optical designs for MWIR and four quadrant detectors by using beam steering methods in missile applications

    NASA Astrophysics Data System (ADS)

    Sakarya, Doǧan Uǧur

    2017-10-01

    Beam steering optical arrangement needs less volume envelope for same field of regard than other gimbal approaches. Both for imaging and four quadrant missile applications, volume is critical parameter limiting system performance. Therefore, a conceptual design of beam steering method has been focused on both imaging and four quadrant missiles. In this study; four different optical designs have been made by using both beam steering and regular method for mid-wave infra-red imaging and four quadrant systems. Optical designs performances have been illustrated in simulation results. By using manufactured Risley prisms, some experimental results are conducted to compare simulations results.

  7. Histostitcher™: An informatics software platform for reconstructing whole-mount prostate histology using the extensible imaging platform framework

    PubMed Central

    Toth, Robert J.; Shih, Natalie; Tomaszewski, John E.; Feldman, Michael D.; Kutter, Oliver; Yu, Daphne N.; Paulus, John C.; Paladini, Ginaluca; Madabhushi, Anant

    2014-01-01

    Context: Co-registration of ex-vivo histologic images with pre-operative imaging (e.g., magnetic resonance imaging [MRI]) can be used to align and map disease extent, and to identify quantitative imaging signatures. However, ex-vivo histology images are frequently sectioned into quarters prior to imaging. Aims: This work presents Histostitcher™, a software system designed to create a pseudo whole mount histology section (WMHS) from a stitching of four individual histology quadrant images. Materials and Methods: Histostitcher™ uses user-identified fiducials on the boundary of two quadrants to stitch such quadrants. An original prototype of Histostitcher™ was designed using the Matlab programming languages. However, clinical use was limited due to slow performance, computer memory constraints and an inefficient workflow. The latest version was created using the extensible imaging platform (XIP™) architecture in the C++ programming language. A fast, graphics processor unit renderer was designed to intelligently cache the visible parts of the histology quadrants and the workflow was significantly improved to allow modifying existing fiducials, fast transformations of the quadrants and saving/loading sessions. Results: The new stitching platform yielded significantly more efficient workflow and reconstruction than the previous prototype. It was tested on a traditional desktop computer, a Windows 8 Surface Pro table device and a 27 inch multi-touch display, with little performance difference between the different devices. Conclusions: Histostitcher™ is a fast, efficient framework for reconstructing pseudo WMHS from individually imaged quadrants. The highly modular XIP™ framework was used to develop an intuitive interface and future work will entail mapping the disease extent from the pseudo WMHS onto pre-operative MRI. PMID:24843820

  8. Application of novel low-intensity nonscanning fluorescence lifetime imaging microscopy for monitoring excited state dynamics in individual chloroplasts and living cells of photosynthetic organisms

    NASA Astrophysics Data System (ADS)

    Eckert, Hann-Jörg; Petrášek, Zdeněk; Kemnitz, Klaus

    2006-10-01

    Picosecond fluorescence lifetime imaging microscopy (FLIM) provides a most valuable tool to analyze the primary processes of photosynthesis in individual cells and chloroplasts of living cells. In order to obtain correct lifetimes of the excited states, the peak intensity of the exciting laser pulses as well as the average intensity has to be sufficiently low to avoid distortions of the kinetics by processes such as singlet-singlet annihilation, closing of the reaction centers or photoinhibition. In the present study this requirement is achieved by non-scanning wide-field FLIM based on time- and space-correlated single-photon counting (TSCSPC) using a novel microchannel plate photomultiplier with quadrant anode (QA-MCP) that allows parallel acquisition of time-resolved images under minimally invasive low-excitation conditions. The potential of the wide-field TCSPC method is demonstrated by presenting results obtained from measurements of the fluorescence dynamics in individual chloroplasts of moss leaves and living cells of the chlorophyll d-containing cyanobacterium Acaryochloris marina.

  9. Examining the Angular Resolution of the Astro-H's Soft X-Ray Telescopes

    NASA Technical Reports Server (NTRS)

    Sato, Toshiki; Iizuka, Ryo; Ishida, Manabu; Kikuchi, Naomichi; Maeda, Yoshitomo; Kurashima, Sho; Nakaniwa, Nozomi; Tomikawa, Kazuki; Hayashi, Takayuki; Mori, Hideyuki; hide

    2016-01-01

    The international x-ray observatory ASTRO-H was renamed Hitomi after launch. It covers a wide energy range from a few hundred eV to 600 keV. It is equipped with two soft x-ray telescopes (SXTs: SXT-I and SXT-S) for imaging the soft x-ray sky up to 12 keV, which focus an image onto the respective focal-plane detectors: CCD camera (SXI) and a calorimeter (SXS). The SXTs are fabricated in a quadrant unit. The angular resolution in half-power diameter (HPD) of each quadrant of the SXTs ranges between 1.1 and 1.4 arc min at 4.51 keV. It was also found that one quadrant has an energy dependence on the HPD. We examine the angular resolution with spot scan measurements. In order to understand the cause of imaging capability deterioration and to reflect it to the future telescope development, we carried out spot scan measurements, in which we illuminate all over the aperture of each quadrant with a square beam 8 mm on a side. Based on the scan results, we made maps of image blurring and a focus position. The former and the latter reflect figure error and positioning error, respectively, of the foils that are within the incident 8 mm x 8 mm beam. As a result, we estimated those errors in a quadrant to be approx. 0.9 to 1.0 and approx. 0.6 to 0.9 arc min, respectively. We found that the larger the positioning error in a quadrant is, the larger its HPD is. The HPD map, which manifests the local image blurring, is very similar from quadrant to quadrant, but the map of the focus position is different from location to location in each telescope. It is also found that the difference in local performance causes energy dependence of the HPD.

  10. Comparison of gonioscopy and anterior segment ocular coherence tomography in detecting angle closure in different quadrants of the anterior chamber angle.

    PubMed

    Sakata, Lisandro M; Lavanya, Raghavan; Friedman, David S; Aung, Han T; Gao, Hong; Kumar, Rajesh S; Foster, Paul J; Aung, Tin

    2008-05-01

    To compare the performance of gonioscopy and anterior segment (AS) optical coherence tomography (OCT) in detecting angle closure in the different quadrants of the anterior chamber angle (ACA). Cross-sectional observational study. Five hundred two consecutive subjects more than 50 years of age with no previous ophthalmic problems recruited from a community clinic in Singapore. All subjects underwent gonioscopy and AS OCT imaging in the dark. Using gonioscopy, the ACA was graded using the Scheie system by a single examiner masked to AS OCT findings. The ACA in a particular quadrant was classified as closed if the posterior trabecular meshwork could not be seen on gonioscopy. A closed ACA on AS OCT imaging was defined by the presence of any contact between the iris and angle wall anterior to the scleral spur. After excluding eyes with poor image quality, a total of 423 right eyes were included in the analysis. A closed angle in at least 1 quadrant was observed in 59% of the eyes by AS OCT and in 33% of the eyes by gonioscopy (P<0.001), with fair agreement between the two methods (kappa = 0.40). The frequency of closed angles by AS OCT and gonioscopy were 48% versus 29% superiorly, 43% versus 22% inferiorly, 18% versus 14% nasally, and 12% versus 20% temporally, respectively. Of the 119 of 1692 quadrants that were closed on gonioscopy but open on AS OCT, a steep iris profile was present in 61 (51%) of 119 quadrants on AS OCT, and of the 276 of 1692 quadrants that were open on gonioscopy but closed on AS OCT, 196 (71%) of 276 quadrants showed short iridoangle contact on AS OCT. The highest rates of closed angles on gonioscopy and AS OCT images were observed in the superior quadrant. Anterior segment OCT tended to detect more closed ACAs than gonioscopy, particularly in the superior and inferior quadrants. Variations in the iris profile and level of iridoangle contact also may explain some of the differences seen between gonioscopy and AS OCT.

  11. Imaging of the iridocorneal angle with the RTVue spectral domain optical coherence tomography.

    PubMed

    Perera, Shamira A; Ho, Ching Lin; Aung, Tin; Baskaran, Mani; Ho, Henrietta; Tun, Tin A; Lee, Tian Loon; Kumar, Rajesh S

    2012-04-02

    To determine the ability of the RTVue spectral domain optical coherence tomography (SDOCT) to image the anterior chamber angle (ACA). Consecutive subjects, recruited from glaucoma clinics, prospectively underwent ophthalmic evaluation including gonioscopy by an ophthalmologist and anterior chamber imaging with SDOCT, adapted with a corneal lens adapter (cornea anterior module-low magnification [CAM-L]) and anterior segment OCT (ASOCT), both performed by a technician. Two different ophthalmologists, masked to gonioscopy findings, assessed visualization of the scleral spur (SS), Schwalbe's line (SL), and trabecular meshwork (TM) by the two modalities. The ability to detect a closed angle was compared with gonioscopy. The average age (SD) of the 81 subjects enrolled was 64.1 (11.4) years; the majority were Chinese (91.4%) and female (61.7%). SDOCT images revealed the SS in 26.9% (56/324) of quadrants and the SL in 44.1% (143/324) of quadrants; in ASOCT images, the SS could be visualized in 69.1% (224/324) of quadrants (P < 0.0001), but the SL was undetectable. The TM was detected equally well (17.3%, P < 0.92) using either device. The angle status was gradable in only 41.7% images with SDOCT, compared with 71.3% of ASOCT images (P < 0.0001). ACA was classified as closed in 19.3% of quadrants (26/135) with SDOCT images and in 44.2% (102/231) with ASOCT images compared with 37.7% (122/324) on gonioscopy. When analyzing the horizontal quadrants only, both modalities agreed well with gonioscopy, 0.75 and 0.74, respectively (AC1 statistics). The RTVue SDOCT allowed visualization of SL, TM, and SS. However, these landmarks were not detected in a large percentage of images.

  12. Evaluating the Patient with Left Lower Quadrant Abdominal Pain.

    PubMed

    Bodmer, Nicholas A; Thakrar, Kiran H

    2015-11-01

    Left lower quadrant pain is a frequent indication for imaging in the emergency department. Most causes of pain originate from the colon, including diverticulitis, colitis, fecal impaction, and epiploic appendagitis. Left-sided urolithiasis and spontaneous hemorrhage in the retroperitoneum or rectus sheath are additional causes of pain. Computed tomography is the preferred imaging modality in the emergent setting for all of these pathologic conditions. Gynecologic, testicular, and neoplastic pathology may also cause left lower quadrant pain but are not discussed in this article. Copyright © 2015 Elsevier Inc. All rights reserved.

  13. Underwater Docking of Autonomous Undersea Vehicles Using Optical Terminal Guidance

    DTIC Science & Technology

    1997-10-01

    simply using a brighter beacon. Scattered light within the field-of-view is imaged almost equally into each of the four quadrants of a photodetector...received by adjacent quadrants a great deal of the forward scattered light can be rejected when the signals from the four quadrants are subsequently...employed to aim the nose of the vehicle at the light source because the illumination is equal in all four quadrants only when the tracker’s optical axis is

  14. Comparison of ultra-widefield fluorescein angiography with the Heidelberg Spectralis(®) noncontact ultra-widefield module versus the Optos(®) Optomap(®).

    PubMed

    Witmer, Matthew T; Parlitsis, George; Patel, Sarju; Kiss, Szilárd

    2013-01-01

    To compare ultra-widefield fluorescein angiography imaging using the Optos(®) Optomap(®) and the Heidelberg Spectralis(®) noncontact ultra-widefield module. Five patients (ten eyes) underwent ultra-widefield fluorescein angiography using the Optos(®) panoramic P200Tx imaging system and the noncontact ultra-widefield module in the Heidelberg Spectralis(®) HRA+OCT system. The images were obtained as a single, nonsteered shot centered on the macula. The area of imaged retina was outlined and quantified using Adobe(®) Photoshop(®) C5 software. The total area and area within each of four visualized quadrants was calculated and compared between the two imaging modalities. Three masked reviewers also evaluated each quadrant per eye (40 total quadrants) to determine which modality imaged the retinal vasculature most peripherally. Optos(®) imaging captured a total retinal area averaging 151,362 pixels, ranging from 116,998 to 205,833 pixels, while the area captured using the Heidelberg Spectralis(®) was 101,786 pixels, ranging from 73,424 to 116,319 (P = 0.0002). The average area per individual quadrant imaged by Optos(®) versus the Heidelberg Spectralis(®) superiorly was 32,373 vs 32,789 pixels, respectively (P = 0.91), inferiorly was 24,665 vs 26,117 pixels, respectively (P = 0.71), temporally was 47,948 vs 20,645 pixels, respectively (P = 0.0001), and nasally was 46,374 vs 22,234 pixels, respectively (P = 0.0001). The Heidelberg Spectralis(®) was able to image the superior and inferior retinal vasculature to a more distal point than was the Optos(®), in nine of ten eyes (18 of 20 quadrants). The Optos(®) was able to image the nasal and temporal retinal vasculature to a more distal point than was the Heidelberg Spectralis(®), in ten of ten eyes (20 of 20 quadrants). The ultra-widefield fluorescein angiography obtained with the Optos(®) and Heidelberg Spectralis(®) ultra-widefield imaging systems are both excellent modalities that provide views of the peripheral retina. On a single nonsteered image, the Optos(®) Optomap(®) covered a significantly larger total retinal surface area, with greater image variability, than did the Heidelberg Spectralis(®) ultra-widefield module. The Optos(®) captured an appreciably wider view of the retina temporally and nasally, albeit with peripheral distortion, while the ultra-widefield Heidelberg Spectralis(®) module was able to image the superior and inferior retinal vasculature more peripherally. The clinical significance of these findings as well as the area imaged on steered montaged images remains to be determined.

  15. Comparison of ultra-widefield fluorescein angiography with the Heidelberg Spectralis® noncontact ultra-widefield module versus the Optos® Optomap®

    PubMed Central

    Witmer, Matthew T; Parlitsis, George; Patel, Sarju; Kiss, Szilárd

    2013-01-01

    Purpose To compare ultra-widefield fluorescein angiography imaging using the Optos® Optomap® and the Heidelberg Spectralis® noncontact ultra-widefield module. Methods Five patients (ten eyes) underwent ultra-widefield fluorescein angiography using the Optos® panoramic P200Tx imaging system and the noncontact ultra-widefield module in the Heidelberg Spectralis® HRA+OCT system. The images were obtained as a single, nonsteered shot centered on the macula. The area of imaged retina was outlined and quantified using Adobe® Photoshop® C5 software. The total area and area within each of four visualized quadrants was calculated and compared between the two imaging modalities. Three masked reviewers also evaluated each quadrant per eye (40 total quadrants) to determine which modality imaged the retinal vasculature most peripherally. Results Optos® imaging captured a total retinal area averaging 151,362 pixels, ranging from 116,998 to 205,833 pixels, while the area captured using the Heidelberg Spectralis® was 101,786 pixels, ranging from 73,424 to 116,319 (P = 0.0002). The average area per individual quadrant imaged by Optos® versus the Heidelberg Spectralis® superiorly was 32,373 vs 32,789 pixels, respectively (P = 0.91), inferiorly was 24,665 vs 26,117 pixels, respectively (P = 0.71), temporally was 47,948 vs 20,645 pixels, respectively (P = 0.0001), and nasally was 46,374 vs 22,234 pixels, respectively (P = 0.0001). The Heidelberg Spectralis® was able to image the superior and inferior retinal vasculature to a more distal point than was the Optos®, in nine of ten eyes (18 of 20 quadrants). The Optos® was able to image the nasal and temporal retinal vasculature to a more distal point than was the Heidelberg Spectralis®, in ten of ten eyes (20 of 20 quadrants). Conclusion The ultra-widefield fluorescein angiography obtained with the Optos® and Heidelberg Spectralis® ultra-widefield imaging systems are both excellent modalities that provide views of the peripheral retina. On a single nonsteered image, the Optos® Optomap® covered a significantly larger total retinal surface area, with greater image variability, than did the Heidelberg Spectralis® ultra-widefield module. The Optos® captured an appreciably wider view of the retina temporally and nasally, albeit with peripheral distortion, while the ultra-widefield Heidelberg Spectralis® module was able to image the superior and inferior retinal vasculature more peripherally. The clinical significance of these findings as well as the area imaged on steered montaged images remains to be determined. PMID:23458976

  16. "Perhaps Irrelevant". The Iconography of Tycho Brahe's Small Gilt Brass Quadrant.

    PubMed

    Perkins, Emma L; Taub, Liba

    2015-01-01

    When Tycho Brahe published a description of his astronomical instruments in 1598 as part of a strategy to procure royal patronage, it was not with one of his grander, precision measurement tools that he opened his account, but rather a small brass quadrant with limited observational utility. The defining feature of this instrument was seemingly a small emblematic image inscribed within the arc of the quadrant. Through this symbolic motif Tycho conveyed a moralising message about the relative worth of astronomy. Considering a range of visual productions that may have influenced his iconography, the present paper situates the quadrant within the broader context of Renaissance visual culture and examines the significance of the quadrant in Tycho's wider instrument collection.

  17. Use of EyeCam for imaging the anterior chamber angle.

    PubMed

    Perera, Shamira A; Baskaran, Mani; Friedman, David S; Tun, Tin A; Htoon, Hla M; Kumar, Rajesh S; Aung, Tin

    2010-06-01

    To compare EyeCam (Clarity Medical Systems, Pleasanton, CA) imaging with gonioscopy for detecting angle closure. In this prospective, hospital-based study, subjects underwent gonioscopy by a single observer and EyeCam imaging by a different operator. EyeCam images were graded by two masked observers. The anterior chamber angle in a quadrant was classified as closed if the trabecular meshwork could not be seen. The eye was classified as having angle closure if two or more quadrants were closed. One hundred fifty-two subjects were studied. The mean age was 57.4 years (SD 12.9) and there were 82 (54%) men. Of the 152 eyes, 21 (13.8%) had angle closure. The EyeCam provided clear images of the angles in 98.8% of subjects. The agreement between the EyeCam and gonioscopy for detecting angle closure in the superior, inferior, nasal, and temporal quadrants based on agreement coefficient (AC1) statistics was 0.73, 0.75, 0.76, and 0.72, respectively. EyeCam detected more closed angles than did gonioscopy in all quadrants (P < 0.05). With gonioscopy, 21/152 (13.8%) eyes were diagnosed as angle closure compared to 41 (27.0%) of 152 with EyeCam (P < 0.001, McNemar Test), giving an overall sensitivity of 76.2% (95% confidence interval [CI], 54.9%-90.7%), specificity of 80.9% (95%CI, 73.5%-87.3%), and an area under the receiver operating characteristic curve (AUC) of 0.79. The EyeCam showed good agreement with gonioscopy for detecting angle closure. However, it detected more closed angles than did gonioscopy in all quadrants.

  18. 64. VIEW FROM THE NORTHEAST IN THE NORTHEAST QUADRANT. DETAIL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    64. VIEW FROM THE NORTHEAST IN THE NORTHEAST QUADRANT. DETAIL VIEW OF THE RIGHT FACE. A PORTION OF THE RIGHT SHOULDER ANGLE IS INCLUDED ON THE LEFT-SIDE OF THE IMAGE, WITH SCALE. - Fort Sumter, Charleston, Charleston County, SC

  19. Northeastern Quadrant of the Caloris Basin

    NASA Image and Video Library

    2000-01-14

    This image, from NASA Mariner 10 spacecraft which launched in 1974, is of the northeastern quadrant of the Caloris basin and shows the smooth hills and domes between the inner and outer scarps and the well-developed radial system east of the outer scarp

  20. Determination of retinal surface area.

    PubMed

    Nagra, Manbir; Gilmartin, Bernard; Thai, Ngoc Jade; Logan, Nicola S

    2017-09-01

    Previous attempts at determining retinal surface area and surface area of the whole eye have been based upon mathematical calculations derived from retinal photographs, schematic eyes and retinal biopsies of donor eyes. 3-dimensional (3-D) ocular magnetic resonance imaging (MRI) allows a more direct measurement, it can be used to image the eye in vivo, and there is no risk of tissue shrinkage. The primary purpose of this study is to compare, using T2-weighted 3D MRI, retinal surface areas for superior-temporal (ST), inferior-temporal (IT), superior-nasal (SN) and inferior-nasal (IN) retinal quadrants. An ancillary aim is to examine whether inter-quadrant variations in area are concordant with reported inter-quadrant patterns of susceptibility to retinal breaks associated with posterior vitreous detachment (PVD). Seventy-three adult participants presenting without retinal pathology (mean age 26.25 ± 6.06 years) were scanned using a Siemens 3-Tesla MRI scanner to provide T2-weighted MR images that demarcate fluid-filled internal structures for the whole eye and provide high-contrast delineation of the vitreous-retina interface. Integrated MRI software generated total internal ocular surface area (TSA). The second nodal point was used to demarcate the origin of the peripheral retina in order to calculate total retinal surface area (RSA) and quadrant retinal surface areas (QRSA) for ST, IT, SN, and IN quadrants. Mean spherical error (MSE) was -2.50 ± 4.03D and mean axial length (AL) 24.51 ± 1.57 mm. Mean TSA and RSA for the RE were 2058 ± 189 and 1363 ± 160 mm 2 , respectively. Repeated measures anova for QRSA data indicated a significant difference within-quadrants (P < 0.01) which, contrasted with ST (365 ± 43 mm 2 ), was significant for IT (340 ± 40 mm 2 P < 0.01), SN (337 ± 40 mm 2 P < 0.01) and IN (321 ± 39 mm 2 P < 0.01) quadrants. For all quadrants, QRSA was significantly correlated with AL (P < 0.01) and exhibited equivalent increases in retinal area/mm increase in AL. Although the differences between QRSAs are relatively small, there was evidence of concordance with reported inter-quadrant patterns of susceptibility to retinal breaks associated with PVD. The data allow AL to be converted to QRSAs, which will assist further work on inter-quadrant structural variation. © 2017 Anatomical Society.

  1. An efficient indexing scheme for binary feature based biometric database

    NASA Astrophysics Data System (ADS)

    Gupta, P.; Sana, A.; Mehrotra, H.; Hwang, C. Jinshong

    2007-04-01

    The paper proposes an efficient indexing scheme for binary feature template using B+ tree. In this scheme the input image is decomposed into approximation, vertical, horizontal and diagonal coefficients using the discrete wavelet transform. The binarized approximation coefficient at second level is divided into four quadrants of equal size and Hamming distance (HD) for each quadrant with respect to sample template of all ones is measured. This HD value of each quadrant is used to generate upper and lower range values which are inserted into B+ tree. The nodes of tree at first level contain the lower and upper range values generated from HD of first quadrant. Similarly, lower and upper range values for the three quadrants are stored in the second, third and fourth level respectively. Finally leaf node contains the set of identifiers. At the time of identification, the test image is used to generate HD for four quadrants. Then the B+ tree is traversed based on the value of HD at every node and terminates to leaf nodes with set of identifiers. The feature vector for each identifier is retrieved from the particular bin of secondary memory and matched with test feature template to get top matches. The proposed scheme is implemented on ear biometric database collected at IIT Kanpur. The system is giving an overall accuracy of 95.8% at penetration rate of 34%.

  2. Demonstration of angle widening using EyeCam after laser peripheral iridotomy in eyes with angle closure.

    PubMed

    Perera, Shamira A; Quek, Desmond T; Baskaran, Mani; Tun, Tin A; Kumar, Rajesh S; Friedman, David S; Aung, Tin

    2010-06-01

    To evaluate EyeCam in detecting changes in angle configuration after laser peripheral iridotomy (LPI) in comparison to gonioscopy, the reference standard. Prospective comparative study. Twenty-four subjects (24 eyes) with primary angle-closure glaucoma (PACG) were recruited. Gonioscopy and EyeCam (Clarity Medical Systems) imaging of all 4 angle quadrants were performed, before and 2 weeks after LPI. Images were graded according to angle structures visible by an observer masked to clinical data or the status of LPI, and were performed in a random order. Angle closure in a quadrant was defined as the inability to visualize the posterior trabecular meshwork. We determined the number of quadrants with closed angles and the mean number of clock hours of angle closure before and after LPI in comparison to gonioscopy. Using EyeCam, all 24 eyes showed at least 1 quadrant of angle widening after LPI. The mean number of clock hours of angle closure decreased significantly, from 8.15 +/- 3.47 clock hours before LPI to 1.75 +/- 2.27 clock hours after LPI (P < .0001, Wilcoxon signed rank test). Overall, gonioscopy showed 1.0 +/- 1.41 (95% CI, 0.43-1.57) quadrants opening from closed to open after LPI compared to 2.0 +/- 1.28 (95% CI, 1.49-2.51, P = .009) quadrants with EyeCam. Intra-observer reproducibility of grading the extent of angle closure in clock hours in EyeCam images was moderate to good (intraclass correlation coefficient 0.831). EyeCam may be used to document changes in angle configuration after LPI in eyes with PACG. Copyright 2010 Elsevier Inc. All rights reserved.

  3. Sequential imaging of asymptomatic carotid atheroma using ultrasmall superparamagnetic iron oxide-enhanced magnetic resonance imaging: a feasibility study.

    PubMed

    Sadat, Umar; Howarth, Simon P S; Usman, Ammara; Tang, Tjun Y; Graves, Martin J; Gillard, Jonathan H

    2013-11-01

    Inflammation within atheromatous plaques is a known risk factor for plaque vulnerability. This can be detected in vivo on high-resolution magnetic resonance imaging (MRI) using ultrasmall superparamagnetic iron oxide (USPIO) contrast medium. The purpose of this study was to assess the feasibility of performing sequential USPIO studies over a 1-year period. Ten patients with moderate asymptomatic carotid stenosis underwent carotid MRI imaging both before and 36 hours after USPIO infusion at 0, 6, and 12 months. Images were manually segmented into quadrants, and the signal change per quadrant was calculated at these time points. A mixed repeated measures statistical model was used to determine signal change attributable to USPIO uptake over time. All patients remained asymptomatic during the study. The mixed model revealed no statistical difference in USPIO uptake between the 3 time points. Intraclass correlation coefficients revealed a good agreement of quadrant signal pre-USPIO infusion between 0 and 6 months (0.70) and 0 and 12 months (0.70). Good agreement of quadrant signal after USPIO infusion was shown between 0 and 6 months (0.68) and moderate agreement was shown between 0 and 12 months (0.33). USPIO-enhanced sequential MRI of atheromatous carotid plaques is clinically feasible. This may have important implications for future longitudinal studies involving pharmacologic intervention in large patient cohorts. Copyright © 2013 National Stroke Association. Published by Elsevier Inc. All rights reserved.

  4. Comparison of Scheimpflug imaging and spectral domain anterior segment optical coherence tomography for detection of narrow anterior chamber angles.

    PubMed

    Grewal, D S; Brar, G S; Jain, R; Grewal, S P S

    2011-05-01

    To compare the performance of anterior chamber volume (ACV) and anterior chamber depth (ACD) obtained using Scheimpflug imaging with angle opening distance (AOD500) and trabecular-iris space area (TISA500) obtained using spectral domain anterior segment optical coherence tomography (SD-ASOCT) in detecting narrow angles classified using gonioscopy. In this prospective, cross-sectional observational study, 265 eyes of 265 consecutive patients underwent sequential Scheimpflug imaging, SD-ASOCT imaging, and gonioscopy. Correlations between gonioscopy grading, ACV, ACD, AOD500, and TISA500 were evaluated. Area under receiver operating characteristic curve (AUC), sensitivity, specificity, and likelihood ratios (LRs) were calculated to assess the performance of ACV, ACD, AOD500, and TISA500 in detecting narrow angles (defined as Shaffer grade ≤1 in all quadrants). SD-ASOCT images were obtained at the nasal and temporal quadrants only. Twenty-eight eyes (10.6%) were classified as narrow angles on gonioscopy. ACV correlated with gonioscopy grading (P<0.001) for temporal (r=0.204), superior (r=0.251), nasal (r=0.213), and inferior (r=0.236) quadrants. ACV correlated with TISA500 for nasal (r=0.135, P=0.029) and temporal (P=0.160, P=0.009) quadrants and also with AOD500 for nasal (r=0.498, P<0.001) and temporal (r=0.517, P<0.001) quadrants. For detection of narrow angles, ACV (AUC=0.935; 95% confidence interval (CI) =0.898-0.961) performed similar to ACD (AUC=0.88, P=0.06) and significantly better than AOD500 nasal (AUC=0.761, P=0.001), AOD500 temporal (AUC=0.808, P<0.001), TISA500 nasal (AUC=0.756, P<0.001), and TISA500 temporal (AUC=0.738, P<0.001). Using a cutoff of 113 mm(3), ACV had 90% sensitivity and 88% specificity for detecting narrow angles. Positive and negative LRs for ACV were 8.63 (95% CI=7.4-10.0) and 0.11 (95% CI=0.03-0.4), respectively. ACV measurements using Scheimpflug imaging outperformed AOD500 and TISA500 using SD-ASOCT for detecting narrow angles.

  5. New Subarray Readout Patterns for the ACS Wide Field Channel

    NASA Astrophysics Data System (ADS)

    Golimowski, D.; Anderson, J.; Arslanian, S.; Chiaberge, M.; Grogin, N.; Lim, Pey Lian; Lupie, O.; McMaster, M.; Reinhart, M.; Schiffer, F.; Serrano, B.; Van Marshall, M.; Welty, A.

    2017-04-01

    At the start of Cycle 24, the original CCD-readout timing patterns used to generate ACS Wide Field Channel (WFC) subarray images were replaced with new patterns adapted from the four-quadrant readout pattern used to generate full-frame WFC images. The primary motivation for this replacement was a substantial reduction of observatory and staff resources needed to support WFC subarray bias calibration, which became a new and challenging obligation after the installation of the ACS CCD Electronics Box Replacement during Servicing Mission 4. The new readout patterns also improve the overall efficiency of observing with WFC subarrays and enable the processing of subarray images through stages of the ACS data calibration pipeline (calacs) that were previously restricted to full-frame WFC images. The new readout patterns replace the original 512×512, 1024×1024, and 2048×2046-pixel subarrays with subarrays having 2048 columns and 512, 1024, and 2048 rows, respectively. Whereas the original square subarrays were limited to certain WFC quadrants, the new rectangular subarrays are available in all four quadrants. The underlying bias structure of the new subarrays now conforms with those of the corresponding regions of the full-frame image, which allows raw frames in all image formats to be calibrated using one contemporaneous full-frame "superbias" reference image. The original subarrays remain available for scientific use, but calibration of these image formats is no longer supported by STScI.

  6. Preliminary Quantification of Image Color Gradient on Genesis Concentrator Silicon Carbine Target 60001

    NASA Technical Reports Server (NTRS)

    Allton, J. H.; Calaway, M. J.; Rodriquez, M. C.

    2008-01-01

    The Genesis spacecraft concentrator was a device to focus solar wind ions onto a 6-cm diameter target area, thus concentrating the solar wind by 20X [1]. The target area was comprised of 4 quadrants held in place by a gold-coated stainless steel "cross" (Fig. 1). To date, two SiC and one chemical vapor deposited (CVD) quadrants have been imaged at 5X using a Leica DM-6000M in autoscan mode. Complete imaging of SiC sample 60001 required 1036 images. The mosaic of images is shown in Fig. 2 and position of analyzed areas in Fig. 3. This mosaic imaging is part of the curatorial documentation of surface condition and mapping of contamination. Higher magnification (50X) images of selected areas of the target and individual contaminant particles are compiled into reports which may be requested from the Genesis Curator [2].

  7. Anterior Segment Imaging Predicts Incident Gonioscopic Angle Closure.

    PubMed

    Baskaran, Mani; Iyer, Jayant V; Narayanaswamy, Arun K; He, Yingke; Sakata, Lisandro M; Wu, Renyi; Liu, Dianna; Nongpiur, Monisha E; Friedman, David S; Aung, Tin

    2015-12-01

    To investigate the incidence of gonioscopic angle closure after 4 years in subjects with gonioscopically open angles but varying degrees of angle closure detected on anterior segment optical coherence tomography (AS OCT; Visante; Carl Zeiss Meditec, Dublin, CA) at baseline. Prospective, observational study. Three hundred forty-two subjects, mostly Chinese, 50 years of age or older, were recruited, of whom 65 were controls with open angles on gonioscopy and AS OCT at baseline, and 277 were cases with baseline open angles on gonioscopy but closed angles (1-4 quadrants) on AS OCT scans. All subjects underwent gonioscopy and AS OCT at baseline (horizontal and vertical single scans) and after 4 years. The examiner performing gonioscopy was masked to the baseline and AS OCT data. Angle closure in a quadrant was defined as nonvisibility of the posterior trabecular meshwork by gonioscopy and visible iridotrabecular contact beyond the scleral spur in AS OCT scans. Gonioscopic angle closure in 2 or 3 quadrants after 4 years. There were no statistically significant differences in age, ethnicity, or gender between cases and controls. None of the control subjects demonstrated gonioscopic angle closure after 4 years. Forty-eight of the 277 subjects (17.3%; 95% confidence interval [CI], 12.8-23; P < 0.0001) with at least 1 quadrant of angle closure on AS OCT at baseline demonstrated gonioscopic angle closure in 2 or more quadrants, whereas 28 subjects (10.1%; 95% CI, 6.7-14.6; P < 0.004) demonstrated gonioscopic angle closure in 3 or more quadrants after 4 years. Individuals with more quadrants of angle closure on baseline AS OCT scans had a greater likelihood of gonioscopic angle closure developing after 4 years (P < 0.0001, chi-square test for trend for both definitions of angle closure). Anterior segment OCT imaging at baseline predicts incident gonioscopic angle closure after 4 years among subjects who have gonioscopically open angles and iridotrabecular contact on AS OCT at baseline. Copyright © 2015 American Academy of Ophthalmology. All rights reserved.

  8. Qualitative Assessment of Ultrasound Biomicroscopic Images Using Standard Photographs: The Liwan Eye Study

    PubMed Central

    Jiang, Yuzhen; Huang, Wenyong; Huang, Qunxiao; Zhang, Jian; Foster, Paul J.

    2010-01-01

    Objective. To classify anatomic features related to anterior chamber angles by a qualitative assessment system based on ultrasound biomicroscopy (UBM) images. Methods. Cases of primary angle-closure suspect (PACS), defined by pigmented trabecular meshwork that is not visible in two or more quadrants on static gonioscopy (cases) and systematically selected subjects (1 of every 10) who did not meet this criterion (controls) were enrolled during a population-based survey in Guangzhou, China. All subjects underwent UBM examination. A set of standard UBM images was used to qualitatively classify anatomic features related to the angle configuration, including iris thickness, iris convexity, iris angulation, ciliary body size, and ciliary process position. All analysis was conducted on right eye images. Results. Based on the qualitative grades, the difference in overall iris thickness between gonioscopically narrow eyes (n = 117) and control eyes (n = 57) was not statistically significant. The peripheral one third of the iris tended to be thicker in all quadrants of the PACS eyes, although the difference was statistically significant only in the superior quadrant (P = 0.008). No significant differences were found in the qualitative classifications of iris insertion, iris angulation, ciliary body size, and ciliary process position. The findings were similar when compared with the control group of eyes with wide angles in all quadrants. Conclusions. Basal iris thickness seems to be more relevant to narrow angle configuration than to overall iris thickness. Otherwise, the anterior rotation and size of the ciliary body, the iris insertion, and the overall iris thickness are comparable in narrow- and wide-angle eyes. PMID:19834039

  9. Right Lower Quadrant Pain in a Young Female: Ultrasound Diagnosis of Rectus Abdominis Tear.

    PubMed

    Minardi, Joseph; Shaver, Erica; Monseau, Aaron; Pratt, Adam; Layman, Shelley M

    2015-11-01

    Right lower quadrant pain in young females presents a frequent diagnostic challenge for emergency physicians, with a broad differential and several important diagnoses. Using an "ultrasound first" imaging strategy can help decrease the use of computed tomography scans, with associated savings in radiation exposure, cost, and other resource use. We report a case of right lower quadrant pain in a young woman. After her initial history and physical examination, appendicitis was the leading differential. A bedside ultrasound was performed, leading to the uncommon diagnosis of rectus abdominis muscle tear. The sonographic findings of a muscle tear include increase in size, loss of linear, homogeneous architecture, and decreased echogenicity. Making this diagnosis at the bedside using ultrasound obviated the need for further imaging, avoiding unnecessary radiation exposure, and decreasing emergency department length of stay and overall cost, while leading to a tailored treatment plan. Why Should an Emergency Physician Be Aware of This? Rectus abdominis tear is a cause of right lower quadrant pain that may mimic appendicitis and should be considered in patients with this complaint. The ability to make this diagnosis with bedside ultrasound may assist in several important patient-oriented outcomes. Copyright © 2015 Elsevier Inc. All rights reserved.

  10. Comparison of Scheimpflug imaging and spectral domain anterior segment optical coherence tomography for detection of narrow anterior chamber angles

    PubMed Central

    Grewal, D S; Brar, G S; Jain, R; Grewal, S P S

    2011-01-01

    Purpose To compare the performance of anterior chamber volume (ACV) and anterior chamber depth (ACD) obtained using Scheimpflug imaging with angle opening distance (AOD500) and trabecular-iris space area (TISA500) obtained using spectral domain anterior segment optical coherence tomography (SD-ASOCT) in detecting narrow angles classified using gonioscopy. Methods In this prospective, cross-sectional observational study, 265 eyes of 265 consecutive patients underwent sequential Scheimpflug imaging, SD-ASOCT imaging, and gonioscopy. Correlations between gonioscopy grading, ACV, ACD, AOD500, and TISA500 were evaluated. Area under receiver operating characteristic curve (AUC), sensitivity, specificity, and likelihood ratios (LRs) were calculated to assess the performance of ACV, ACD, AOD500, and TISA500 in detecting narrow angles (defined as Shaffer grade ≤1 in all quadrants). SD-ASOCT images were obtained at the nasal and temporal quadrants only. Results Twenty-eight eyes (10.6%) were classified as narrow angles on gonioscopy. ACV correlated with gonioscopy grading (P<0.001) for temporal (r=0.204), superior (r=0.251), nasal (r=0.213), and inferior (r=0.236) quadrants. ACV correlated with TISA500 for nasal (r=0.135, P=0.029) and temporal (P=0.160, P=0.009) quadrants and also with AOD500 for nasal (r=0.498, P<0.001) and temporal (r=0.517, P<0.001) quadrants. For detection of narrow angles, ACV (AUC=0.935; 95% confidence interval (CI) =0.898–0.961) performed similar to ACD (AUC=0.88, P=0.06) and significantly better than AOD500 nasal (AUC=0.761, P=0.001), AOD500 temporal (AUC=0.808, P<0.001), TISA500 nasal (AUC=0.756, P<0.001), and TISA500 temporal (AUC=0.738, P<0.001). Using a cutoff of 113 mm3, ACV had 90% sensitivity and 88% specificity for detecting narrow angles. Positive and negative LRs for ACV were 8.63 (95% CI=7.4–10.0) and 0.11 (95% CI=0.03–0.4), respectively. Conclusions ACV measurements using Scheimpflug imaging outperformed AOD500 and TISA500 using SD-ASOCT for detecting narrow angles. PMID:21336254

  11. Earth Observations taken by STS-115 crewmember

    NASA Image and Video Library

    2006-09-19

    S115-E-07595 (19 Sept. 2006) --- A crewmember aboard the Space Shuttle Atlantis recorded this digital still image of part of the eastern Mediterranean area. The Gulf of Suez, Gulf of Aqaba, Dead Sea, Tel Aviv and Jerusalem all are visible in the upper left quadrant. Jordan is in the lower left quadrant. The Golan Heights and Haifa appear in the lower right quarter.

  12. The quadrant method measuring four points is as a reliable and accurate as the quadrant method in the evaluation after anatomical double-bundle ACL reconstruction.

    PubMed

    Mochizuki, Yuta; Kaneko, Takao; Kawahara, Keisuke; Toyoda, Shinya; Kono, Norihiko; Hada, Masaru; Ikegami, Hiroyasu; Musha, Yoshiro

    2017-11-20

    The quadrant method was described by Bernard et al. and it has been widely used for postoperative evaluation of anterior cruciate ligament (ACL) reconstruction. The purpose of this research is to further develop the quadrant method measuring four points, which we named four-point quadrant method, and to compare with the quadrant method. Three-dimensional computed tomography (3D-CT) analyses were performed in 25 patients who underwent double-bundle ACL reconstruction using the outside-in technique. The four points in this study's quadrant method were defined as point1-highest, point2-deepest, point3-lowest, and point4-shallowest, in femoral tunnel position. Value of depth and height in each point was measured. Antero-medial (AM) tunnel is (depth1, height2) and postero-lateral (PL) tunnel is (depth3, height4) in this four-point quadrant method. The 3D-CT images were evaluated independently by 2 orthopaedic surgeons. A second measurement was performed by both observers after a 4-week interval. Intra- and inter-observer reliability was calculated by means of intra-class correlation coefficient (ICC). Also, the accuracy of the method was evaluated against the quadrant method. Intra-observer reliability was almost perfect for both AM and PL tunnel (ICC > 0.81). Inter-observer reliability of AM tunnel was substantial (ICC > 0.61) and that of PL tunnel was almost perfect (ICC > 0.81). The AM tunnel position was 0.13% deep, 0.58% high and PL tunnel position was 0.01% shallow, 0.13% low compared to quadrant method. The four-point quadrant method was found to have high intra- and inter-observer reliability and accuracy. This method can evaluate the tunnel position regardless of the shape and morphology of the bone tunnel aperture for use of comparison and can provide measurement that can be compared with various reconstruction methods. The four-point quadrant method of this study is considered to have clinical relevance in that it is a detailed and accurate tool for evaluating femoral tunnel position after ACL reconstruction. Case series, Level IV.

  13. Site-specific adaptive remodeling of Greyhound metacarpal cortical bone subjected to asymmetrical cyclic loading.

    PubMed

    Johnson, K A; Skinner, G A; Muir, P

    2001-05-01

    To quantify geometric, inertial, and histomorphometric properties at the mid-diaphyseal level of left and right metacarpal bones (MCB) of racing Greyhounds. MCB from 7 racing Greyhounds euthanatized for reasons unrelated to MCB abnormalities. Mid-diaphyseal transverse sections of left and right MCB were stained with H&E or microradiographed. Images of stained sections were digitized, and cross-sectional area, cortical area, and maximum and minimum area moments of inertia of each bone were determined. Histomorphometric data (osteonal density, osteonal birefringence, and endosteal new lamellar bone thickness) were collected in 4 quadrants (dorsal, palmar, lateral, medial). Values were compared between limbs and among bones and quadrants. Cross-sectional area, cortical area, and maximum and minimum moments of inertia of left MCB-IV and -V were significantly greater, compared with contralateral bones. Overall osteonal densities in the dorsal quadrants of left MCB were greater, compared with lateral and medial quadrants. Also, percentage of birefringent osteons was significantly greater in the dorsal quadrant of left MCB-III, -IV, and -V, compared with the palmar quadrant. Thickness of new endosteal lamellar bone was not significantly influenced by limb, bone, or quadrant. Increased cortical thickness and geometric properties of left MCB-IV and -V of Greyhounds, together with altered turnover and orientation of osteons in the dorsal quadrants of left MCB, are site-specific adaptive responses associated with asymmetric cyclic loading as a result of racing on circular tracks. Site-specific adaptive remodeling may be important in the etiopathogenesis of fatigue fractures in racing Greyhounds.

  14. Correcting sample drift using Fourier harmonics.

    PubMed

    Bárcena-González, G; Guerrero-Lebrero, M P; Guerrero, E; Reyes, D F; Braza, V; Yañez, A; Nuñez-Moraleda, B; González, D; Galindo, P L

    2018-07-01

    During image acquisition of crystalline materials by high-resolution scanning transmission electron microscopy, the sample drift could lead to distortions and shears that hinder their quantitative analysis and characterization. In order to measure and correct this effect, several authors have proposed different methodologies making use of series of images. In this work, we introduce a methodology to determine the drift angle via Fourier analysis by using a single image based on the measurements between the angles of the second Fourier harmonics in different quadrants. Two different approaches, that are independent of the angle of acquisition of the image, are evaluated. In addition, our results demonstrate that the determination of the drift angle is more accurate by using the measurements of non-consecutive quadrants when the angle of acquisition is an odd multiple of 45°. Copyright © 2018 Elsevier Ltd. All rights reserved.

  15. Space Weathering of the Lunar Surface by Solar Wind Particles

    NASA Astrophysics Data System (ADS)

    Kim, Sungsoo S.; Sim, Chaekyung

    2017-08-01

    The lunar regolith is space-weathered to a different degree in response to the different fluxes of incident solar wind particles and micrometeoroids. Crater walls, among other slating surfaces, are good tracers of the space-weathering process because they mature differently depending on the varying incident angles of weathering agents. We divide a crater wall into four quadrants (north, south, east, and west) and analyze the distribution of 950-nm/750-nm reflectance-ratio and 750-nm reflectance values in each wall quadrant, using the topography-corrected images by Multispectral Imager (MI) onboard SELENE (Kaguya). For thousands of impact craters across the Moon, we interpret the spectral distributions in the four wall quadrants in terms of the space weathering by solar wind particles and micrometeoroids and of gardening by meteroids. We take into account the solar-wind shielding by the Earth’s magnetotail to correctly assess the different spectral behaviors between east- and west-facing walls of the craters in the near-side of the Moon.

  16. The Preflight Photometric Calibration of the Extreme-Ultraviolet Imaging Telescope EIT

    NASA Technical Reports Server (NTRS)

    Dere, K. P.; Moses, J. D.; Delaboudiniere, J. -P.; Brunaud, J.; Carabetian, C.; Hochedez, J. -F.; Song, X. Y.; Catura, R. C.; Clette, F.; Defise, J. -M.

    2000-01-01

    This paper presents the preflight photometric calibration of the Extreme-ultraviolet Imaging Telescope (EIT) aboard the Solar and Heliospheric Observatory (SOHO). The EIT consists of a Ritchey-Chretien telescope with multilayer coatings applied to four quadrants of the primary and secondary mirrors, several filters and a backside-thinned CCD detector. The quadrants of the EIT optics were used to observe the Sun in 4 wavelength bands that peak near 171, 195, 284, and 304 . Before the launch of SOHO, the EIT mirror reflectivities, the filter transmissivities and the CCD quantum efficiency were measured and these values are described here. The instrumental throughput in terms of an effective area is presented for each of the various mirror quadrant and filter wheel combinations. The response to a coronal plasma as a function of temperature is also determined and the expected count rates are compared to the count rates observed in a coronal hole, the quiet Sun and an active region.

  17. Earth observation taken by the Expedition 29 crew

    NASA Image and Video Library

    2011-11-16

    ISS029-E-042846 (16 Nov. 2011) --- Parts of the U.S. and Mexico are seen in this image photographed by one of the Expedition 29 crew members from the International Space Station as it flew above the Pacific Ocean on Nov. 16, 2011. The Salton Sea is in the center of the frame, with the Gulf of Cortez, Mexico's Baja California and the Colorado River in the upper right quadrant. The Los Angeles Basin and Santa Catalina and San Clemente islands are at the bottom center edge of the image. Lake Mead and the Las Vegas area of Nevada even made it into the frame in the upper left quadrant.

  18. Postoperative MRI Evaluation of a Radiofrequency Cordotomy Lesion for Intractable Cancer Pain

    PubMed Central

    Vedantam, A.; Hou, P.; Chi, T.L.; Hess, K.R; Dougherty, P.M.; Bruera, E.; Viswanathan, A.

    2017-01-01

    BACKGROUND AND PURPOSE There are limited data on the use of postoperative imaging to evaluate the cordotomy lesion. We aimed to describe the cordotomy lesion by using postoperative MR imaging in patients after percutaneous cordotomy for intractable cancer pain. MATERIALS AND METHODS Postoperative MR imaging and clinical outcomes were prospectively obtained for 10 patients after percutaneous cordotomy for intractable cancer pain. Area, signal intensity, and location of the lesion were recorded. Clinical outcomes were measured by using the Visual Analog Scale and the Brief Pain Inventory–Short Form, and correlations with MR imaging metrics were evaluated. RESULTS Ten patients (5 men, 5 women; mean age, 58.5 ± 9.6 years) were included in this study. The cordotomy lesion was hyperintense with central hypointense foci on T2-weighted MR imaging, and it was centered in the anterolateral quadrant at the C1–C2 level. The mean percentage of total cord area lesioned was 24.9% ± 7.9%, and most lesions were centered in the dorsolateral region of the anterolateral quadrant (66% of the anterolateral quadrant). The number of pial penetrations correlated with the percentage of total cord area that was lesioned (r = 0.78; 95% CI, 0.44–0.89; P = .008) and the length of T2-weighted hyperintensity (r = 0.85; 95% CI, 0.54–0.89; P = .002). No significant correlations were found between early clinical outcomes and quantitative MR imaging metrics. CONCLUSIONS We describe qualitative and quantitative characteristics of a cordotomy lesion on early postoperative MR imaging. The size and length of the lesion on MR imaging correlate with the number of pial penetrations. Larger studies are needed to further investigate the clinical correlates of MR imaging metrics after percutaneous cordotomy. PMID:28209581

  19. Noninvasive imaging of human foveal capillary network using dual-conjugate adaptive optics.

    PubMed

    Popovic, Zoran; Knutsson, Per; Thaung, Jörgen; Owner-Petersen, Mette; Sjöstrand, Johan

    2011-04-22

    To demonstrate noninvasive imaging of human foveal capillary networks with a high-resolution, wide-field, dual-conjugate adaptive optics (DCAO) imaging instrument. The foveal capillary networks of five healthy subjects with no previous history of ocular or neurologic disease or surgery were imaged with a novel high-resolution, wide-field DCAO instrument. The foveal avascular zone (FAZ) in each image was defined using a manual procedure. An automated algorithm based on publicly available and custom-written software was used to identify vessels and extract morphologic FAZ and vessel parameters. Capillary densities were calculated in two annular regions of interest (ROIs) outside the FAZ (500 μm and 750 μm outer radius from the foveal center) and in the superior, inferior, temporal, and nasal quadrants within the two ROIs. Mean FAZ area was 0.302 ± 0.100 mm(2), and mean capillary density (length/area) in the inner ROI was 38.0 ± 4.0 mm(-1) and 36.4 ± 4.0 mm(-1) in the outer ROI. The difference in ROI capillary density was not significant. There was no significant difference in quadrant capillary density within the two ROIs or between quadrants irrespective of ROI. The authors have demonstrated a technique for noninvasive imaging and semiautomated detection and analysis of foveal capillaries. In comparison with other studies, their method yielded lower capillary densities than histology but similar results to the current clinical gold standard, fluorescein angiography. The increased field of view of the DCAO instrument opens up new possibilities for high-resolution noninvasive clinical imaging of foveal capillaries.

  20. California: San Joaquin Valley

    Atmospheric Science Data Center

    2014-05-15

    ...     View Larger Image This illustration features Multi-angle Imaging SpectroRadiometer ... quadrant is a map of haze amount determined from automated processing of the MISR imagery. Low amounts of haze are shown in blue, and a ...

  1. Verifying placement of small-bore feeding tubes: electromagnetic device images versus abdominal radiographs.

    PubMed

    Bryant, Vera; Phang, Jean; Abrams, Kevin

    2015-11-01

    Clinicians are unsure if radiography is needed to confirm correct positioning of feeding tubes inserted with assistance from an electromagnetic system. To compare radiographic reports of feeding tube placement with images generated by an electromagnetic feeding tube placement device. The medical records of 200 consecutive patients who had feeding tubes inserted with assistance from an electromagnetic feeding tube placement device were reviewed retrospectively. Radiographic reports of tube site were compared with images generated by the device. Radiographic evidence of tube sites was available in 188 cases: 184 tubes were located in portions of the gastrointestinal tract. Ninety of the 188 tubes were situated in the optimal site (distal duodenum or jejunum) radiographically. Images generated by the electromagnetic device were available in 176 cases; of these, 52 tubes appeared to end in the expected left lower quadrant. Tubes shown on radiographs to be in other sites also occasionally appeared to end in the left lower quadrant. Nurses using the device did not recognize 4 of the 188 tubes (2.1%) that were inadvertently placed in the lung. No consistent pattern of quadrant distribution was found for tubes positioned in the stomach or proximal duodenum. Images generated by the electromagnetic tube placement device provided inconsistent results regarding tube location. A small percentage of seriously malpositioned tubes were not detected by using the electromagnetic device. These findings do not support eliminating radiographs to confirm correct tube placement following use of an electromagnetic tube placement device. ©2015 American Association of Critical-Care Nurses.

  2. SELF CALIBRATED STMR ARRAY FOR MATERIAL CHARACTERIZATION AND SHM OF ORTHOTROPIC PLATE-LIKE STRUCTURES

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vishnuvardhan, J.; Muralidharan, Ajith; Balasubramaniam, Krishnan

    A full ring STMR array patch had been used for Structural Health Monitoring (SHM) of anisotropic materials where the elastic moduli, correspond to the virgin sample, were used in the calculations. In the present work an in-situ SHM has been successfully demonstrated using a novel compact sensor patch (Double ring single quadrant small footprint STMR array) through simultaneous reconstruction of the elastic moduli, material symmetry, orientation of principal planes and defect imaging. The direct received signals were used to measure Lamb wave velocities, which were used in a slowness based reconstructed algorithm using Genetic Algorithm to reconstruct the elastic moduli,more » material symmetry and orientation of principal planes. The measured signals along with the reconstructed elastic moduli were used in the phased addition algorithm for imaging the damages present on the structure. To show the applicability of the method, simulations were carried out with the double ring single quadrant STMR array configuration to image defects and are compared with the images obtained using simulation data of the full ring STMR array configuration. The experimental validation has been carried out using 3.15 mm quasi-isotropic graphite-epoxy composite. The double ring single quadrant STMR array has advantages over the full ring STMR array as it can carry out in-situ SHM with limited footprint on the structure.« less

  3. Comparison of the inflammatory burden of truly asymptomatic carotid atheroma with atherosclerotic plaques contralateral to symptomatic carotid stenosis: an ultra small superparamagnetic iron oxide enhanced magnetic resonance study

    PubMed Central

    Tang, Tjun Y; Howarth, Simon P S; Miller, Sam R; Graves, Martin J; U‐King‐Im, Jean‐Marie; Trivedi, Rikin A; Li, Zhi Yong; Walsh, Stewart R; Brown, Andrew P; Kirkpatrick, Peter J; Gaunt, Michael E; Gillard, Jonathan H

    2007-01-01

    Background Inflammation is a recognised risk factor for the vulnerable atherosclerotic plaque. The aim of this study was to explore whether there is a difference in the degree of magnetic resonance (MR) defined inflammation using ultra small superparamagnetic iron oxide (USPIO) particles within carotid atheroma in completely asymptomatic individuals and the asymptomatic carotid stenosis contralateral to the symptomatic side. Methods 20 symptomatic patients with contralateral disease and 20 completely asymptomatic patients underwent multi‐sequence MR imaging before and 36 h after USPIO infusion. Images were manually segmented into quadrants and signal change in each quadrant was calculated following USPIO administration. Mean signal change was compared across all quadrants in the two groups. Results The mean percentage of quadrants showing signal loss was 53% in the contralateral group compared with 31% in completely asymptomatic individuals (p = 0.025). The mean percentages showing enhancement were 44% and 65%, respectively (p = 0.024). The mean signal difference between the two groups was 8.6% (95% CI 1.6% to 15.6%; p = 0.017). Conclusions Truly asymptomatic plaques seem to demonstrate inflammation but not to the extent of the contralateral asymptomatic stenosis to the symptomatic side. Inflammatory activity may be a significant risk factor in asymptomatic disease. PMID:17578854

  4. Radiation imaging apparatus

    DOEpatents

    Anger, Hal O.; Martin, Donn C.; Lampton, Michael L.

    1983-01-01

    A radiation imaging system using a charge multiplier and a position sensitive anode in the form of periodically arranged sets of interconnected anode regions for detecting the position of the centroid of a charge cloud arriving thereat from the charge multiplier. Various forms of improved position sensitive anodes having single plane electrode connections are disclosed. Various analog and digital signal processing systems are disclosed, including systems which use the fast response of microchannel plates, anodes and preamps to perform scintillation pulse height analysis digitally.

  5. Automatic image acquisition processor and method

    DOEpatents

    Stone, William J.

    1986-01-01

    A computerized method and point location system apparatus is disclosed for ascertaining the center of a primitive or fundamental object whose shape and approximate location are known. The technique involves obtaining an image of the object, selecting a trial center, and generating a locus of points having a predetermined relationship with the center. Such a locus of points could include a circle. The number of points overlying the object in each quadrant is obtained and the counts of these points per quadrant are compared. From this comparison, error signals are provided to adjust the relative location of the trial center. This is repeated until the trial center overlies the geometric center within the predefined accuracy limits.

  6. Right Upper Quadrant Pain: Ultrasound First!

    PubMed

    Revzin, Margarita V; Scoutt, Leslie M; Garner, Joseph G; Moore, Christopher L

    2017-10-01

    Acute right upper quadrant (RUQ) pain is a common presenting symptom in emergency departments and outpatient medical practices, and is most commonly attributable to biliary and hepatic pathology. Ultrasound should be used as a first-line imaging modality for the diagnosis of gallstones and cholecystitis, as it allows the differentiation of medical and surgical causes of upper abdominal pathology, and in many circumstances is sufficient to guide patient management. Knowledge of strengths and limitations of ultrasound in the evaluation of RUQ is paramount in correct diagnosis. A spectrum of RUQ pathology for which a RUQ ultrasound examination should reasonably be considered as the initial imaging modality of choice will be reviewed. © 2017 by the American Institute of Ultrasound in Medicine.

  7. Automatic image acquisition processor and method

    DOEpatents

    Stone, W.J.

    1984-01-16

    A computerized method and point location system apparatus is disclosed for ascertaining the center of a primitive or fundamental object whose shape and approximate location are known. The technique involves obtaining an image of the object, selecting a trial center, and generating a locus of points having a predetermined relationship with the center. Such a locus of points could include a circle. The number of points overlying the object in each quadrant is obtained and the counts of these points per quadrant are compared. From this comparison, error signals are provided to adjust the relative location of the trial center. This is repeated until the trial center overlies the geometric center within the predefined accuracy limits.

  8. Photocopy of photograph (digital image located in LBNL Photo Lab ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of photograph (digital image located in LBNL Photo Lab Collection, XBD200503-00117-047). March 2005. AREA OF MAGNET REMOVAL, NORTHEAST QUADRANT, BEVATRON - University of California Radiation Laboratory, Bevatron, 1 Cyclotron Road, Berkeley, Alameda County, CA

  9. Photocopy of photograph (digital image located in LBNL Photo Lab ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of photograph (digital image located in LBNL Photo Lab Collection, XBD200503-00117-012). March 2005. PASSAGEWAY UNDER QUADRANT AND DIFFUSION PUMPS, BEVATRON - University of California Radiation Laboratory, Bevatron, 1 Cyclotron Road, Berkeley, Alameda County, CA

  10. A Comparative Evaluation of Adherence of Microorganism to Different Types of Brackets: A Scanning Electron Microscopic Study.

    PubMed

    Shashidhar, E P; Sahitya, M; Sunil, T; Murthy, Anup R; Rani, M S

    2015-09-01

    The purpose of this study was to evaluate and compare the adherence of microorganism to different types of brackets using the scanning electron microscope (SEM). A double-blinded study was undertaken to evaluate and adherence of microorganisms to different types of brackets using SEM. At random, 12 patients reporting for treatment to the department of Orthodontics VS Dental College and Hospital were selected. Four types of brackets were included in the present study stainless steel, titanium, composite, and ceramic. Brackets were bonded to teeth of the patient on all the four quadrants. The teeth included for bonding were lateral incisor, canine, first premolar, and second premolar. The brackets were left for 72 h. After 72 h brackets were debonded, and they were evaluated by SEM for adherence of microorganism in the slot and tie wings surface. The SEM images were graded, and the adherence of microorganism to the brackets in the surfaces and the four different quadrants were recorded. There is a significant difference in adherence of microorganisms to the various types of brackets (P < 0.001) and the surfaces (P < 0.05) included in the study. However, there is no significance in the mean adherence of microorganisms in the different quadrants (P > 0.05) included in the study. The interaction of bracket/surface, bracket/quadrant, surface/quadrants was analyzed, there was no significance of comparison of bracket/surfaces/quadrant but the interaction of bracket/quadrant was found to be significant (<0.011). The interaction of bracket/surfaces/quadrant was also found to be significant (<0.003). The maximum adherence of microorganisms was observed with the composite bracket material and the least adherence of microorganisms was observed with the titanium bracket material. The adherence of microorganisms is relatively more in the slot area, when compare to the tie wings surface maximum adherence of microorganism is observed in the upper left quadrant and least adherence of microorganism is observed in the lower right quadrant. There is a significant difference in adherence of microorganisms to various types of brackets and the surfaces included in the study. There is no significant difference in the adherence of microorganism to the bracket surfaces in the four quadrants included in the study.

  11. A Comparative Evaluation of Adherence of Microorganism to Different Types of Brackets: A Scanning Electron Microscopic Study

    PubMed Central

    Shashidhar, E P; Sahitya, M; Sunil, T; Murthy, Anup R; Rani, M S

    2015-01-01

    Background: The purpose of this study was to evaluate and compare the adherence of microorganism to different types of brackets using the scanning electron microscope (SEM). A double-blinded study was undertaken to evaluate and adherence of microorganisms to different types of brackets using SEM. Materials and Methods: At random, 12 patients reporting for treatment to the department of Orthodontics VS Dental College and Hospital were selected. Four types of brackets were included in the present study stainless steel, titanium, composite, and ceramic. Brackets were bonded to teeth of the patient on all the four quadrants. The teeth included for bonding were lateral incisor, canine, first premolar, and second premolar. The brackets were left for 72 h. After 72 h brackets were debonded, and they were evaluated by SEM for adherence of microorganism in the slot and tie wings surface. The SEM images were graded, and the adherence of microorganism to the brackets in the surfaces and the four different quadrants were recorded. Results: There is a significant difference in adherence of microorganisms to the various types of brackets (P < 0.001) and the surfaces (P < 0.05) included in the study. However, there is no significance in the mean adherence of microorganisms in the different quadrants (P > 0.05) included in the study. The interaction of bracket/surface, bracket/quadrant, surface/quadrants was analyzed, there was no significance of comparison of bracket/surfaces/quadrant but the interaction of bracket/quadrant was found to be significant (<0.011). The interaction of bracket/surfaces/quadrant was also found to be significant (<0.003). Conclusion: The maximum adherence of microorganisms was observed with the composite bracket material and the least adherence of microorganisms was observed with the titanium bracket material. The adherence of microorganisms is relatively more in the slot area, when compare to the tie wings surface maximum adherence of microorganism is observed in the upper left quadrant and least adherence of microorganism is observed in the lower right quadrant. There is a significant difference in adherence of microorganisms to various types of brackets and the surfaces included in the study. There is no significant difference in the adherence of microorganism to the bracket surfaces in the four quadrants included in the study. PMID:26435612

  12. Radiation imaging apparatus

    DOEpatents

    Anger, H.O.; Martin, D.C.; Lampton, M.L.

    1983-07-26

    A radiation imaging system using a charge multiplier and a position sensitive anode in the form of periodically arranged sets of interconnected anode regions for detecting the position of the centroid of a charge cloud arriving thereat from the charge multiplier. Various forms of improved position sensitive anodes having single plane electrode connections are disclosed. Various analog and digital signal processing systems are disclosed, including systems which use the fast response of microchannel plates, anodes and preamps to perform scintillation pulse height analysis digitally. 15 figs.

  13. Photocopy of photograph (digital image located in LBNL Photo Lab ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of photograph (digital image located in LBNL Photo Lab Collection, XBD200503-00117-005). March 2005. PASSAGEWAY UNDER SOUTHEAST QUADRANT, AIR DUCT OPENINGS, BEVATRON - University of California Radiation Laboratory, Bevatron, 1 Cyclotron Road, Berkeley, Alameda County, CA

  14. Photocopy of photograph (digital image located in LBNL Photo Lab ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of photograph (digital image located in LBNL Photo Lab Collection, XBD200503-00117-009). March 2005. OPENINGS OF AIR DUCTS INTO PASSAGEWAY UNDER SOUTHEAST QUADRANT, BEVATRON - University of California Radiation Laboratory, Bevatron, 1 Cyclotron Road, Berkeley, Alameda County, CA

  15. Peripapillary nerve fiber layer thickness measurement reproducibility using optical coherence tomography.

    PubMed

    Villain, Max A; Greenfield, David S

    2003-01-01

    To assess reproducibility of quadrantic and clock hour sectors of retinal nerve fiber layer thickness in normal eyes using optical coherence tomography. Normal eyes of healthy volunteers meeting eligibility criteria were imaged by two inexperienced operators. Six 360 degrees circular scans with a diameter of 3.4 mm centered on the optic disc were obtained during each scanning session, and a baseline image was formed using 3 high-quality images defined by the software. Images were obtained on three different days within a 4-week period. Variance and coefficient of variation (CV) were calculated for quadrantic and retinal nerve fiber layer clock hour sectors obtained from the baseline image. Five normal eyes were scanned. Intraoperator reproducibility was high. The mean (+/- SD) CV for total retinal nerve fiber layer thickness was 5.3 +/- 3.82% and 4.33 +/- 3.7% for operators 1 and 2, respectively. Interoperator reproducibility was good with statistically similar variance for all quadrantic and clock hour retinal nerve fiber layer parameters (P = .42 to .99). The nasal retinal nerve fiber layer was the most variable sector for both operators (mean CV: 10.42% and 7.83% for operators 1 and 2, respectively). Differences in mean total, nasal, temporal, and superior retinal nerve fiber layer thickness were not statistically significant between operators for all eyes; however, for inferior retinal nerve fiber layer thickness, there was a significant (P = .0007) difference between operators in one eye. Peripapillary retinal nerve fiber layer thickness assessments using optical coherence tomography have good intraoperator and interoperator reproducibility. Inexperienced operators can generate useful measurement data with acceptable levels of variance.

  16. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Russ, M; Shankar, A; Lau, A

    Purpose: Demonstrate and quantify the augmented resolution due to focalspot size decrease in images acquired on the anode side of the field, for both small and medium (0.3 and 0.6mm) focal-spot sizes using the experimental task-based GM-ROD metric. Theoretical calculations have shown that a medium focal-spot can achieve the resolution of a small focal-spot if acquired with a tilted anode, effectively providing a higher-output small focal-spot. Methods: The MAF-CMOS (micro-angiographic fluoroscopic complementary-metal-oxide semiconductor) detector (75µm pixel pitch) imaged two copper wire segments of different diameter and a pipeline stent at the central axis and on the anode side of themore » beam, achieved by tilting the x-ray C-arm (Toshiba Infinix) to 6° and realigning the detector with the perpendicular ray to correct for x-ray obliquity. The relative gain in resolution was determined using the GM-ROD metric, which compares images on the basis of the Fourier transform of the image and the measured NNPS. To emphasize the geometric unsharpness, images were acquired at a magnification of two. Results: Images acquired on the anode side were compared to those acquired on the central axis with the same target-area focal-spot to consider the effect of an angled tube, and for all three objects the advantage of the smaller effective focal-spot was clear, showing a maximum improvement of 36% in GM-ROD. The images obtained with the small focal-spot at the central axis were compared to those of the medium focal-spot at the anode side and, for all objects, the relative performance was comparable. Conclusion: For three objects, the GM-ROD demonstrated the advantage of the anode side focal-spot. The comparable performance of the medium focal-spot on the anode side will allow for a high-output small focal-spot; a necessity in endovascular image-guided interventions. Partial support from an NIH grant R01EB002873 and an equipment grant from Toshiba Medical Systems Corp.« less

  17. Behavioral biases when viewing multiplexed scenes: scene structure and frames of reference for inspection

    PubMed Central

    Stainer, Matthew J.; Scott-Brown, Kenneth C.; Tatler, Benjamin W.

    2013-01-01

    Where people look when viewing a scene has been a much explored avenue of vision research (e.g., see Tatler, 2009). Current understanding of eye guidance suggests that a combination of high and low-level factors influence fixation selection (e.g., Torralba et al., 2006), but that there are also strong biases toward the center of an image (Tatler, 2007). However, situations where we view multiplexed scenes are becoming increasingly common, and it is unclear how visual inspection might be arranged when content lacks normal semantic or spatial structure. Here we use the central bias to examine how gaze behavior is organized in scenes that are presented in their normal format, or disrupted by scrambling the quadrants and separating them by space. In Experiment 1, scrambling scenes had the strongest influence on gaze allocation. Observers were highly biased by the quadrant center, although physical space did not enhance this bias. However, the center of the display still contributed to fixation selection above chance, and was most influential early in scene viewing. When the top left quadrant was held constant across all conditions in Experiment 2, fixation behavior was significantly influenced by the overall arrangement of the display, with fixations being biased toward the quadrant center when the other three quadrants were scrambled (despite the visual information in this quadrant being identical in all conditions). When scenes are scrambled into four quadrants and semantic contiguity is disrupted, observers no longer appear to view the content as a single scene (despite it consisting of the same visual information overall), but rather anchor visual inspection around the four separate “sub-scenes.” Moreover, the frame of reference that observers use when viewing the multiplex seems to change across viewing time: from an early bias toward the display center to a later bias toward quadrant centers. PMID:24069008

  18. False Color Mosaic of Jupiter Belt-Zone Boundary

    NASA Image and Video Library

    1997-12-18

    This false color mosaic shows a belt-zone boundary near Jupiter equator. The images that make up the four quadrants of this mosaic were taken within a few minutes of each other. These images were taken on Nov. 5, 1996 by NASA Galileo orbiter.

  19. Comparison of distribution of lung aeration measured with EIT and CT in spontaneously breathing, awake patients1.

    PubMed

    Radke, Oliver C; Schneider, Thomas; Braune, Anja; Pirracchio, Romain; Fischer, Felix; Koch, Thea

    2016-09-28

    Both Electrical Impedance Tomography (EIT) and Computed Tomography (CT) allow the estimation of the lung area. We compared two algorithms for the detection of the lung area per quadrant from the EIT images with the lung areas derived from the CT images. 39 outpatients who were scheduled for an elective CT scan of the thorax were included in the study. For each patient we recorded EIT images immediately before the CT scan. The lung area per quadrant was estimated from both CT and EIT data using two different algorithms for the EIT data. Data showed considerable variation during spontaneous breathing of the patients. Overall correlation between EIT and CT was poor (0.58-0.77), the correlation between the two EIT algorithms was better (0.90-0.92). Bland-Altmann analysis revealed absence of bias, but wide limits of agreement. Lung area estimation from CT and EIT differs significantly, most probably because of the fundamental difference in image generation.

  20. A Look at Hurricane Matthew from NASA AIRS

    NASA Image and Video Library

    2016-10-06

    Hurricane Matthew, currently an extremely dangerous Category 4 storm on the Saffir-Simpson Hurricane Wind Scale, continues to bear down on the southeastern United States. At 11:27 a.m. PDT (2:27 p.m. EDT and 18:23 UT) today, NASA's Atmospheric Infrared Sounder (AIRS) instrument aboard NASA's Aqua satellite observed the storm as its eye was passing over the Bahamas. An AIRS false-color infrared image shows that the northeast and southwest quadrants of the storm had the coldest cloud tops, denoting the regions of the storm where the strongest precipitation was occurring at the time. Data from the Advanced Microwave Sounding Unit (AMSU), another of AIRS' suite of instruments, indicate that the northeast quadrant, which appears smaller in the infrared image, likely had the most intense rain bands at the time. The AIRS infrared image shows that at the time of the image the storm had full circulation, with a small eye surrounded by a thick eye wall and can be seen at http://photojournal.jpl.nasa.gov/catalog/PIA21092.

  1. Photocopy of photograph (digital image located in LBNL Photo Lab ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of photograph (digital image located in LBNL Photo Lab Collection, XBD200503-00117-049). March 2005. TUNNEL ENTRY FROM MAIN FLOOR OF MAGNET ROOM INTO CENTER OF BEVATRON, BENEATH SOUTHWEST QUADRANT - University of California Radiation Laboratory, Bevatron, 1 Cyclotron Road, Berkeley, Alameda County, CA

  2. Optical synthesizer for a large quadrant-array CCD camera: Center director's discretionary fund

    NASA Technical Reports Server (NTRS)

    Hagyard, Mona J.

    1992-01-01

    The objective of this program was to design and develop an optical device, an optical synthesizer, that focuses four contiguous quadrants of a solar image on four spatially separated CCD arrays that are part of a unique CCD camera system. This camera and the optical synthesizer will be part of the new NASA-Marshall Experimental Vector Magnetograph, and instrument developed to measure the Sun's magnetic field as accurately as present technology allows. The tasks undertaken in the program are outlined and the final detailed optical design is presented.

  3. In vivo imaging of palisades of Vogt in dry eye versus normal subjects using en-face spectral-domain optical coherence tomography.

    PubMed

    Ghouali, Wajdene; Tahiri Joutei Hassani, Rachid; Djerada, Zoubir; Liang, Hong; El Sanharawi, Mohamed; Labbé, Antoine; Baudouin, Christophe

    2017-01-01

    To evaluate a possible clinical application of spectral-domain optical coherence tomography (SD-OCT) using en-face module for the imaging of the corneoscleral limbus in normal subjects and dry eye patients. Seventy-six subjects were included in this study. Seventy eyes of 35 consecutive patients with dry eye disease and 82 eyes of 41 healthy control subjects were investigated. All subjects were examined with the Avanti RTVue® anterior segment OCT. En-face OCT images of the corneoscleral limbus were acquired in four quadrants (inferior, superior, nasal and temporal) and then were analyzed semi-quantitatively according to whether or not palisades of Vogt (POV) were visible. En-face OCT images were then compared to in vivo confocal microscopy (IVCM) in eleven eyes of 7 healthy and dry eye patients. En-face SD-OCT showed POV as a radially oriented network, located in superficial corneoscleral limbus, with a good correlation with IVCM features. It provided an easy and reproducible identification of POV without any special preparation or any direct contact, with a grading scale from 0 (no visualization) to 3 (high visualization). The POV were found predominantly in superior (P<0.001) and inferior (P<0.001) quadrants when compared to the nasal and temporal quadrants for all subjects examined. The visibility score decreased with age (P<0.001) and was lower in dry eye patients (P<0.01). In addition, the score decreased in accordance with the severity of dry eye disease (P<0.001). En-face SD-OCT is a non-contact imaging technique that can be used to evaluate the POV, thus providing valuable information about differences in the limbal anatomy of dry eye patients as compared to healthy patients.

  4. Wedge-and-strip anodes for centroid-finding position-sensitive photon and particle detectors

    NASA Technical Reports Server (NTRS)

    Martin, C.; Jelinsky, P.; Lampton, M.; Malina, R. F.

    1981-01-01

    The paper examines geometries employing position-dependent charge partitioning to obtain a two-dimensional position signal from each detected photon or particle. Requiring three or four anode electrodes and signal paths, images have little distortion and resolution is not limited by thermal noise. An analysis of the geometrical image nonlinearity between event centroid location and the charge partition ratios is presented. In addition, fabrication and testing of two wedge-and-strip anode systems are discussed. Images obtained with EUV radiation and microchannel plates verify the predicted performance, with further resolution improvements achieved by adopting low noise signal circuitry. Also discussed are the designs of practical X-ray, EUV, and charged particle image systems.

  5. Development of 10×10 Matrix-anode MCP-PMT

    NASA Astrophysics Data System (ADS)

    Yang, Jie; Li, Yongbin; Xu, Pengxiao; Zhao, Wenjin

    2018-02-01

    10×10 matrix-anode is developed by high-temperature co-fired ceramics (HTCC) technology. Based on the new matrix-anode, a new kind of photon counting imaging detector - 10×10 matrix-anode MCP-PMT is developed, and its performance parameters are tested. HTCC technology is suitable for the MCP-PMT's air impermeability and its baking process. Its response uniformity is better than the metal-ceramic or metal-glass sealing anode, and it is also a promising method to realize a higher density matrix-anode.

  6. PN-CCD camera for XMM: performance of high time resolution/bright source operating modes

    NASA Astrophysics Data System (ADS)

    Kendziorra, Eckhard; Bihler, Edgar; Grubmiller, Willy; Kretschmar, Baerbel; Kuster, Markus; Pflueger, Bernhard; Staubert, Ruediger; Braeuninger, Heinrich W.; Briel, Ulrich G.; Meidinger, Norbert; Pfeffermann, Elmar; Reppin, Claus; Stoetter, Diana; Strueder, Lothar; Holl, Peter; Kemmer, Josef; Soltau, Heike; von Zanthier, Christoph

    1997-10-01

    The pn-CCD camera is developed as one of the focal plane instruments for the European photon imaging camera (EPIC) on board the x-ray multi mirror (XMM) mission to be launched in 1999. The detector consists of four quadrants of three pn-CCDs each, which are integrated on one silicon wafer. Each CCD has 200 by 64 pixels (150 micrometer by 150 micrometers) with 280 micrometers depletion depth. One CCD of a quadrant is read out at a time, while the four quadrants can be processed independently of each other. In standard imaging mode the CCDs are read out sequentially every 70 ms. Observations of point sources brighter than 1 mCrab will be effected by photon pile- up. However, special operating modes can be used to observe bright sources up to 150 mCrab in timing mode with 30 microseconds time resolution and very bright sources up to several crab in burst mode with 7 microseconds time resolution. We have tested one quadrant of the EPIC pn-CCD camera at line energies from 0.52 keV to 17.4 keV at the long beam test facility Panter in the focus of the qualification mirror module for XMM. In order to test the time resolution of the system, a mechanical chopper was used to periodically modulate the beam intensity. Pulse periods down to 0.7 ms were generated. This paper describes the performance of the pn-CCD detector in timing and burst readout modes with special emphasis on energy and time resolution.

  7. Angle assessment by EyeCam, goniophotography, and gonioscopy.

    PubMed

    Baskaran, Mani; Perera, Shamira A; Nongpiur, Monisha E; Tun, Tin A; Park, Judy; Kumar, Rajesh S; Friedman, David S; Aung, Tin

    2012-09-01

    To compare EyeCam (Clarity Medical Systems, Pleasanton, CA) and goniophotography in detecting angle closure, using gonioscopy as the reference standard. In this hospital-based, prospective, cross-sectional study, participants underwent gonioscopy by a single observer, and EyeCam imaging and goniophotography by different operators. The anterior chamber angle in a quadrant was classified as closed if the posterior trabecular meshwork could not be seen. A masked observer categorized the eyes as per the number of closed quadrants, and an eye was classified as having angle closure if there were 2 or more quadrants of closure. Agreement between the methods was analyzed by κ statistic and comparison of area under receiver operating characteristic curves (AUC). Eighty-five participants (85 eyes) were included, the majority of whom were Chinese. Angle closure was detected in 38 eyes (45%) with gonioscopy, 40 eyes (47%) using EyeCam, and 40 eyes (47%) with goniophotography (P=0.69 in both comparisons, McNemar test). The agreement for angle closure diagnosis (by eye) between gonioscopy and the 2 imaging modalities was high (κ=0.86; 95% Confidence Interval (CI), 0.75-0.97), whereas the agreement between EyeCam and goniophotography was not as good (κ=0.72; 95% CI, 0.57-0.87); largely due to lack of agreement in the nasal and temporal quadrants (κ=0.55 to 0.67). The AUC for detecting eyes with gonioscopic angle closure was similar for goniophotography and EyeCam (AUC 0.93, sensitivity=94.7%, specificity=91.5%; P>0.95). EyeCam and goniophotography have similarly high sensitivity and specificity for the detection of gonioscopic angle closure.

  8. Multi-anode microchannel arrays - New detectors for imaging and spectroscopy in space

    NASA Technical Reports Server (NTRS)

    Timothy, J. G.; Bybee, R. L.

    1983-01-01

    Consideration is given to the construction and operation of multi-anode microchannel array detector systems having formats as large as 256 x 1024 pixels. Such arrays are being developed for imaging and spectroscopy at soft X-ray, ultraviolet and visible wavelengths from balloons, sounding rockets and space probes. Both discrete-anode and coincidence-anode arrays are described. Two types of photocathode structures are evaluated: an opaque photocathode deposited directly on the curved-channel MCP and an activated cathode deposited on a proximity-focused mesh. Future work will include sensitivity optimization in the different wavelength regions and the development of detector tubes with semitransparent proximity-focused photocathodes.

  9. An analog RF gap voltage regulation system for the Advanced Photon Source storage ring.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Horan, D.

    1999-04-13

    An analog rf gap voltage regulation system has been designed and built at Argonne National Laboratory to maintain constant total storage ring rf gap voltage, independent of beam loading and cavity tuning effects. The design uses feedback control of the klystron mod-anode voltage to vary the amount of rf power fed to the storage ring cavities. The system consists of two independent feedback loops, each regulating the combined rf gap voltages of eight storage ring cavities by varying the output power of either one or two rf stations, depending on the mode of operation. It provides full operator control andmore » permissive logic to permit feedback control of the rf system output power only if proper conditions are met. The feedback system uses envelope-detected cavity field probe outputs as the feedback signal. Two different methods of combining the individual field probe signals were used to generate a relative DC level representing one-half of the total storage ring rf voltage, an envelope-detected vector sum of the field probe rf signals, and the DC sum of individual field probe envelope detector outputs. The merits of both methods are discussed. The klystron high-voltage power supply (HVPS) units are fitted with an analog interface for external control of the mod-anode voltage level, using a four-quadrant analog multiplier to modulate the HVPS mod-anode voltage regulator set-point in response to feedback system commands.« less

  10. Some practicable applications of quadtree data structures/representation in astronomy

    NASA Technical Reports Server (NTRS)

    Pasztor, L.

    1992-01-01

    Development of quadtree as hierarchical data structuring technique for representing spatial data (like points, regions, surfaces, lines, curves, volumes, etc.) has been motivated to a large extent by storage requirements of images, maps, and other multidimensional (spatially structured) data. For many spatial algorithms, time-efficiency of quadtrees in terms of execution may be as important as their space-efficiency concerning storage conditions. Briefly, the quadtree is a class of hierarchical data structures which is based on the recursive partition of a square region into quadrants and sub-quadrants until a predefined limit. Beyond the wide applicability of quadtrees in image processing, spatial information analysis, and building digital databases (processes becoming ordinary for the astronomical community), there may be numerous further applications in astronomy. Some of these practicable applications based on quadtree representation of astronomical data are presented and suggested for further considerations. Examples are shown for use of point as well as region quadtrees. Statistics of different leaf and non-leaf nodes (homogeneous and heterogeneous sub-quadrants respectively) at different levels may provide useful information on spatial structure of astronomical data in question. By altering the principle guiding the decomposition process, different types of spatial data may be focused on. Finally, a sampling method based on quadtree representation of an image is proposed which may prove to be efficient in the elaboration of sampling strategy in a region where observations were carried out previously either with different resolution or/and in different bands.

  11. Reassignment of scattered emission photons in multifocal multiphoton microscopy.

    PubMed

    Cha, Jae Won; Singh, Vijay Raj; Kim, Ki Hean; Subramanian, Jaichandar; Peng, Qiwen; Yu, Hanry; Nedivi, Elly; So, Peter T C

    2014-06-05

    Multifocal multiphoton microscopy (MMM) achieves fast imaging by simultaneously scanning multiple foci across different regions of specimen. The use of imaging detectors in MMM, such as CCD or CMOS, results in degradation of image signal-to-noise-ratio (SNR) due to the scattering of emitted photons. SNR can be partly recovered using multianode photomultiplier tubes (MAPMT). In this design, however, emission photons scattered to neighbor anodes are encoded by the foci scan location resulting in ghost images. The crosstalk between different anodes is currently measured a priori, which is cumbersome as it depends specimen properties. Here, we present the photon reassignment method for MMM, established based on the maximum likelihood (ML) estimation, for quantification of crosstalk between the anodes of MAPMT without a priori measurement. The method provides the reassignment of the photons generated by the ghost images to the original spatial location thus increases the SNR of the final reconstructed image.

  12. Effects of the voltage and time of anodization on modulation of the pore dimensions of AAO films for nanomaterials synthesis

    NASA Astrophysics Data System (ADS)

    Chahrour, Khaled M.; Ahmed, Naser M.; Hashim, M. R.; Elfadill, Nezar G.; Maryam, W.; Ahmad, M. A.; Bououdina, M.

    2015-12-01

    Highly-ordered and hexagonal-shaped nanoporous anodic aluminum oxide (AAO) of 1 μm thickness of Al pre-deposited onto Si substrate using two-step anodization was successfully fabricated. The growth mechanism of the porous AAO film was investigated by anodization current-time behavior for different anodizing voltages and by visualizing the microstructural procedure of the fabrication of AAO film by two-step anodization using cross-sectional and top view of FESEM imaging. Optimum conditions of the process variables such as annealing time of the as-deposited Al thin film and pore widening time of porous AAO film were experimentally determined to obtain AAO films with uniformly distributed and vertically aligned porous microstructure. Pores with diameter ranging from 50 nm to 110 nm and thicknesses between 250 nm and 1400 nm, were obtained by controlling two main influential anodization parameters: the anodizing voltage and time of the second-step anodization. X-ray diffraction analysis reveals amorphous-to-crystalline phase transformation after annealing at temperatures above 800 °C. AFM images show optimum ordering of the porous AAO film anodized under low voltage condition. AAO films may be exploited as templates with desired size distribution for the fabrication of CuO nanorod arrays. Such nanostructured materials exhibit unique properties and hold high potential for nanotechnology devices.

  13. High-frame rate multiport CCD imager and camera

    NASA Astrophysics Data System (ADS)

    Levine, Peter A.; Patterson, David R.; Esposito, Benjamin J.; Tower, John R.; Lawler, William B.

    1993-01-01

    A high frame rate visible CCD camera capable of operation up to 200 frames per second is described. The camera produces a 256 X 256 pixel image by using one quadrant of a 512 X 512 16-port, back illuminated CCD imager. Four contiguous outputs are digitally reformatted into a correct, 256 X 256 image. This paper details the architecture and timing used for the CCD drive circuits, analog processing, and the digital reformatter.

  14. Multi-nucleate retinal pigment epithelium cells of the human macula exhibit a characteristic and highly specific distribution.

    PubMed

    Starnes, Austin C; Huisingh, Carrie; McGwin, Gerald; Sloan, Kenneth R; Ablonczy, Zsolt; Smith, R Theodore; Curcio, Christine A; Ach, Thomas

    2016-01-01

    The human retinal pigment epithelium (RPE) is reportedly 3% bi-nucleated. The importance to human vision of multi-nucleated (MN)-RPE cells could be clarified with more data about their distribution in central retina. Nineteen human RPE-flatmounts (9 ≤ 51 years, 10 > 80 years) were imaged at 12 locations: 3 eccentricities (fovea, perifovea, near periphery) in 4 quadrants (superior, inferior, temporal, nasal). Image stacks of lipofuscin-attributable autofluorescence and phalloidin labeled F-actin cytoskeleton were obtained using a confocal fluorescence microscope. Nuclei were devoid of autofluorescence and were marked using morphometric software. Cell areas were approximated by Voronoi regions. Mean number of nuclei per cell among eccentricity/quadrant groups and by age were compared using Poisson and binominal regression models. A total of 11,403 RPE cells at 200 locations were analyzed: 94.66% mono-, 5.31% bi-, 0.02% tri-nucleate, and 0.01% with 5 nuclei. Age had no effect on number of nuclei. There were significant regional differences: highest frequencies of MN-cells were found at the perifovea (9.9%) and near periphery (6.8%). The fovea lacked MN-cells almost entirely. The nasal quadrant had significantly more MN-cells compared to other quadrants, at all eccentricities. This study demonstrates MN-RPE cells in human macula. MN-cells may arise due to endoreplication, cell fusion, or incomplete cell division. The topography of MN-RPE cells follows the topography of photoreceptors; with near-absence at the fovea (cones only) and high frequency at perifovea (highest rod density). This distribution might reflect specific requirements of retinal metabolism or other mechanisms addressable in further studies.

  15. Peripapillary Choroidal Thickness Variation With Age and Race in Normal Eyes

    PubMed Central

    Rhodes, Lindsay A.; Huisingh, Carrie; Johnstone, John; Fazio, Massimo A.; Smith, Brandon; Wang, Lan; Clark, Mark; Downs, J. Crawford; Owsley, Cynthia; Girard, Michael J. A.; Mari, Jean Martial; Girkin, Christopher A.

    2015-01-01

    Purpose. This study examined the association between peripapillary choroidal thickness (PCT) with age and race in a group of African descent (AD) and European descent (ED) subjects with normal eyes. Methods. Optic nerve head images from enhanced depth imaging spectral-domain optical coherence tomography of 166 normal eyes from 84 subjects of AD and ED were manually delineated to identify the principal surfaces of Bruch's membrane (BM), Bruch's membrane opening (BMO), and anterior sclera (AS). Peripapillary choroidal thickness was measured between BM and AS at increasing distance away from BMO. The mean PCT was compared between AD and ED subjects and generalized estimating equation (GEE) regression analysis was used to examine the association between race and PCT overall, in each quadrant, and by distance from BMO. Models were adjusted for age, BMO area, and axial length in the regression analysis. Results. Overall, the mean PCT increased from 63.9 μm ± 18.1 at 0 to 250 μm to 170.3 μm ± 56.7 at 1500 to 2000 μm from BMO. Individuals of AD had a greater mean PCT than those of ED at all distances from BMO (P < 0.05 at each distance) and in each quadrant (P < 0.05 in each quadrant). Results from multivariate regression indicate that ED subjects had significantly lower PCT compared to AD overall and in all quadrants and distances from BMO. Increasing age was also significantly associated with a lower PCT in both ED and AD participants. Conclusions. Peripapillary choroidal thickness varies with race and age, as individuals of AD have a thicker peripapillary choroid than those of ED. (ClinicalTrials.gov number, NCT00221923.) PMID:25711640

  16. System for forming a quadrified image comprising angularly related fields of view of a three dimensional object

    NASA Technical Reports Server (NTRS)

    Chamberlain, F. R. (Inventor)

    1980-01-01

    A system for generating, within a single frame of photographic film, a quadrified image including images of angularly (including orthogonally) related fields of view of a near field three dimensional object is described. It is characterized by three subsystems each of which includes a plurality of reflective surfaces for imaging a different field of view of the object at a different quadrant of the quadrified image. All of the subsystems have identical path lengths to the object photographed.

  17. Image charge multi-role and function detectors

    NASA Astrophysics Data System (ADS)

    Milnes, James; Lapington, Jon S.; Jagutzki, Ottmar; Howorth, Jon

    2009-06-01

    The image charge technique used with microchannel plate imaging tubes provides several operational and practical benefits by serving to isolate the electronic image readout from the detector. The simple dielectric interface between detector and readout provides vacuum isolation and no vacuum electrical feed-throughs are required. Since the readout is mechanically separate from the detector, an image tube of generic design can be simply optimised for various applications by attaching it to different readout devices and electronics. We present imaging performance results using a single image tube with a variety of readout devices suited to differing applications: (a) A four electrode charge division tetra wedge anode, optimised for best spatial resolution in photon counting mode. (b) A cross delay line anode, enabling higher count rate, and the possibility of discriminating near co-incident events, and an event timing resolution of better than 1 ns. (c) A multi-anode readout connected, either to a multi-channel oscilloscope for analogue measurements of fast optical pulses, or alternately, to a multi-channel time correlated single photon counting (TCSPC) card.

  18. Failure Analysis of Batteries Using Synchrotron-based Hard X-ray Microtomography

    PubMed Central

    Harry, Katherine J.; Parkinson, Dilworth Y.; Balsara, Nitash P.

    2015-01-01

    Imaging morphological changes that occur during the lifetime of rechargeable batteries is necessary to understand how these devices fail. Since the advent of lithium-ion batteries, researchers have known that the lithium metal anode has the highest theoretical energy density of any anode material. However, rechargeable batteries containing a lithium metal anode are not widely used in consumer products because the growth of lithium dendrites from the anode upon charging of the battery causes premature cell failure by short circuit. Lithium dendrites can also form in commercial lithium-ion batteries with graphite anodes if they are improperly charged. We demonstrate that lithium dendrite growth can be studied using synchrotron-based hard X-ray microtomography. This non-destructive imaging technique allows researchers to study the growth of lithium dendrites, in addition to other morphological changes inside batteries, and subsequently develop methods to extend battery life. PMID:26382323

  19. Compact, high-resolution, gamma ray imaging for scintimammography and other medical diagostic applications

    DOEpatents

    Majewski, Stanislaw; Weisenberger, Andrew G.; Wojcik, Randolph F.; Steinbach, Daniela

    1999-01-01

    A high resolution gamma ray imaging device includes an aluminum housing, a lead screen collimator at an opened end of the housing, a crystal scintillator array mounted behind the lead screen collimator, a foam layer between the lead screen collimator and the crystal scintillator array, a photomultiplier window coupled to the crystal with optical coupling grease, a photomultiplier having a dynode chain body and a base voltage divider with anodes, anode wire amplifiers each connected to four anodes and a multi pin connector having pin connections to each anode wire amplifier. In one embodiment the crystal scintillator array includes a yttrium aluminum perovskite (YAP) crystal array. In an alternate embodiment, the crystal scintillator array includes a gadolinium oxyorthosilicate (GSO) crystal array.

  20. CT enterography: Mannitol versus VoLumen.

    PubMed

    Wong, Jessica; Moore, Helen; Roger, Mark; McKee, Chris

    2016-10-01

    Several different neutral oral contrast agents have been trialled in magnetic resonance and CT enterography (CTE). In the Auckland region, Mannitol 2.5% and VoLumen are both used in CTE. This study compares the performance of these two neutral oral contrast agents in CTE. Computed tomography enterography data were collected from 25 consecutive studies that used either Mannitol or VoLumen in 2014. All images were reviewed by three radiologists blinded to the type of oral contrast. Each quadrant was assessed for maximum distension, proportion of bowel loops distended, presence of inhomogeneous content and bowel wall visibility. Assessment also included whether the contrast agent reached the caecum and an overall subjective quality assessment. Patients were invited to answer a questionnaire regarding tolerability of the preparations. Mannitol achieves better wall visibility in the right upper quadrant, left upper quadrant and left lower quadrant (P < 0.01). Overall differences in study quality favours Mannitol (P < 0.01) with 48% of the Mannitol studies being considered excellent compared with 4% of the VoLumen studies. There was no difference in maximal distension or proportion of loops distended. Mannitol in CTE achieves studies of a better quality than and is a viable alternative to VoLumen. © 2016 The Royal Australian and New Zealand College of Radiologists.

  1. Unusual case of acute appendicitis with left upper quadrant abdominal pain.

    PubMed

    Tawk, Charbel M; Zgheib, Rana R; Mehanna, Seba

    2012-01-01

    Acute appendicitis is one of the most frequent causes of surgical abdominal pain presenting to the Emergency Department. The diagnosis is confirmed by a set of clinical signs, blood tests and imaging. The typical presentation consists of periumbilical pain radiating to the right lower quadrant with peritoneal reaction on palpation (Mac Burney). In this article, we report a case of acute appendicitis presenting with a left upper quadrant pain due to intestinal malrotation and we describe the radiologic findings on computed tomography. With an Alvarado score of 4 and a nonconclusive abdominal U/S, the diagnosis of acute appendicitis was a long shot. Persistence of pain and increasing inflammatory parameters in her blood exams pushed the medical team to further investigate and a CT scan revealed intestinal malrotation with acute appendicitis. An examining physician should not be mislead by the atypical presentation of acute appendicitis and should bear in mind the diagnosis to avoid serious complications. Copyright © 2012 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.

  2. In vivo imaging of palisades of Vogt in dry eye versus normal subjects using en-face spectral-domain optical coherence tomography

    PubMed Central

    Djerada, Zoubir; Liang, Hong; El Sanharawi, Mohamed; Labbé, Antoine; Baudouin, Christophe

    2017-01-01

    Purpose To evaluate a possible clinical application of spectral-domain optical coherence tomography (SD-OCT) using en-face module for the imaging of the corneoscleral limbus in normal subjects and dry eye patients. Patients and methods Seventy-six subjects were included in this study. Seventy eyes of 35 consecutive patients with dry eye disease and 82 eyes of 41 healthy control subjects were investigated. All subjects were examined with the Avanti RTVue® anterior segment OCT. En-face OCT images of the corneoscleral limbus were acquired in four quadrants (inferior, superior, nasal and temporal) and then were analyzed semi-quantitatively according to whether or not palisades of Vogt (POV) were visible. En-face OCT images were then compared to in vivo confocal microscopy (IVCM) in eleven eyes of 7 healthy and dry eye patients. Results En-face SD-OCT showed POV as a radially oriented network, located in superficial corneoscleral limbus, with a good correlation with IVCM features. It provided an easy and reproducible identification of POV without any special preparation or any direct contact, with a grading scale from 0 (no visualization) to 3 (high visualization). The POV were found predominantly in superior (P<0.001) and inferior (P<0.001) quadrants when compared to the nasal and temporal quadrants for all subjects examined. The visibility score decreased with age (P<0.001) and was lower in dry eye patients (P<0.01). In addition, the score decreased in accordance with the severity of dry eye disease (P<0.001). Conclusion En-face SD-OCT is a non-contact imaging technique that can be used to evaluate the POV, thus providing valuable information about differences in the limbal anatomy of dry eye patients as compared to healthy patients. PMID:29176786

  3. A position- and time-sensitive photon-counting detector with delay- line read-out

    NASA Astrophysics Data System (ADS)

    Jagutzki, Ottmar; Dangendorf, Volker; Lauck, Ronald; Czasch, Achim; Milnes, James

    2007-05-01

    We have developed image intensifier tubes with delay-anode read-out for time- and position-sensitive photon counting. The timing precision is better than 1 ns with 1000x1000 pixels position resolution and up to one megacounts/s processing rate. Large format detectors of 40 and 75 mm active diameter with internal helical-wire delay-line anodes have been produced and specified. A different type of 40 and 25 mm tubes with semi-conducting screen for image charge read-out allow for an economic and robust tube design and for placing the read-out anodes outside the sealed housing. Two types of external delay-line anodes, i.e. pick-up electrodes for the image charge, have been tested. We present tests of the detector and anode performance. Due to the low background this technique is well suited for applications with very low light intensity and especially if a precise time tagging for each photon is required. As an example we present the application of scintillator read-out in time-of-flight (TOF) neutron radiography. Further applications so far are Fluorescence Life-time Microscopy (FLIM) and Astronomy.

  4. Inexpensive position sensitive detector block for dedicated PET cameras using 40-mm diameter PMT in quadrant sharing configuration

    NASA Astrophysics Data System (ADS)

    Uribe, J.; Aykac, M.; Baghaei, H.; Li, Hongdi; Wang, Yu; Liu, Yaqiang; Wong, V.; Xing, Tao; Ramirez, R.; Wong, Wai-Hoi

    2003-06-01

    Recent approvals by CMS (HCFA) for reimbursement of positron emission tomography (PET) scans fuels the rapid grow of the PET market, thus creating the need for more affordable dedicated PET scanners. The objective of the work presented here was the development of a BGO position-sensitive block with similar detector area (40 mm /spl times/ 40 mm) and same number of crystals (8 /spl times/ 8) as the block of a commercial BGO PET, using the less expensive photomultiplier quadrant sharing (PQS) technique. This block is coupled to four single-anode 40-mm diameter photomultipliers (PMT) instead of the 19-mm PMT used in a popular commercial BGO PET, and each PMT is shared by four adjacent detector blocks. Potentially, this design needs only 25% of the number of PMT used in the commercial BGO PET. In order not to waste the unused half-row of PMT at the edges of a detector panel/module when the module is made up solely of square blocks, an extended rectangular block has to be developed for the edge-blocks in the module, which maximized the use of the PMT and minimized the gap between modules. Only the extended block needs to be developed to derive the design for all the blocks in the module because the symmetric square block uses the same light-distributing partitions as those along the short side of the extended rectangular block. White-paint masks applied with accurate templates and airbrush were fine-tuned for every pair of adjacent crystals. The experimental block developed in this study provided good crystal-decoding. The composite energy spectrum of all 64 crystals showed a prominent photopeak. The worst crystal sitting in the air space between 4 round PMTs still has 60% of the signal pulse height as the best crystal. The average energy resolution was 21.8% for 511 keV gamma (range 17% - 28.7%) that compared well with the 22% - 44% measured with GE and CTI blocks. The image resolution provided by the PQS blocks is expected to be comparable to that of commercial BGO PETs as similar size crystals were decoded.

  5. Analysis of Basis Weight Uniformity of Microfiber Nonwovens and Its Impact on Permeability and Filtration Properties

    NASA Astrophysics Data System (ADS)

    Amirnasr, Elham

    It is widely recognized that nonwoven basis weight non-uniformity affects various properties of nonwovens. However, few studies can be found in this topic. The development of uniformity definition and measurement methods and the study of their impact on various web properties such as filtration properties and air permeability would be beneficial both in industrial applications and in academia. They can be utilized as a quality control tool and would provide insights about nonwoven behaviors that cannot be solely explained by average values. Therefore, for quantifying nonwoven web basis weight uniformity we purse to develop an optical analytical tool. The quadrant method and clustering analysis was utilized in an image analysis scheme to help define "uniformity" and its spatial variation. Implementing the quadrant method in an image analysis system allows the establishment of a uniformity index that can be used to quantify the degree of uniformity. Clustering analysis has also been modified and verified using uniform and random simulated images with known parameters. Number of clusters and cluster properties such as cluster size, member and density was determined. We also utilized this new measurement method to evaluate uniformity of nonwovens produced with different processes and investigated impacts of uniformity on filtration and permeability. The results of quadrant method shows that uniformity index computed from quadrant method demonstrate a good range for non-uniformity of nonwoven webs. Clustering analysis is also been applied on reference nonwoven with known visual uniformity. From clustering analysis results, cluster size is promising to be used as uniformity parameter. It is been shown that non-uniform nonwovens has provide lager cluster size than uniform nonwovens. It was been tried to find a relationship between web properties and uniformity index (as a web characteristic). To achieve this, filtration properties, air permeability, solidity and uniformity index of meltblown and spunbond samples was measured. Results for filtration test show some deviation between theoretical and experimental filtration efficiency by considering different types of fiber diameter. This deviation can occur due to variation in basis weight non-uniformity. So an appropriate theory is required to predict the variation of filtration efficiency with respect to non-uniformity of nonwoven filter media. And the results for air permeability test showed that uniformity index determined by quadrant method and measured properties have some relationship. In the other word, air permeability decreases as uniformity index on nonwoven web increase.

  6. [Vertical retraction syndrome caused by anomalous orbital structures].

    PubMed

    Yang, Qiong; Jiao, Yong-hong; Man, Feng-yuan; Wang, Zhen-chang; Chang, Qing-lin; Lu, Wei; Wang, Jing-hui; Zhao, Kan-xing

    2011-11-01

    To described the clinical feature and MRI imaging of six children with vertical retraction syndrome. Six children with unilateral vertical retraction syndrome between 15 months and 8 years of age, mean age was (5.01 ± 1.27) years old. Strabismus examination included diopter, prism diopters, eye movement examination, binocular vision and fundus examination. Imaging of the ocular motor nerves at the brainstem was performed in 0.8 mm thickness image planes using 3D-FIESTA sequence, the orbits were imaged with FSE T1, T2WI using surface coils, and within 2.0 mm thick planes. Four children showed hypertropia, characterized by limited depression, a light retraction of the globe during downward gaze and eyelid lag. The MRI imaging showed anomalous orbital structure in the superonasal quadrant that between medial rectus and superior rectus or adjacent to the superior rectus. Two children showed intermittent exotropia, characterized by limited elevation, retraction of the globe and narrowing of the palpebral fissure during upward gaze. The MRI imaging showed anomalous orbital structure was present in the inferotemporal quadrant, one originate in inferior rectus and another close to the lateral rectus. Anomalous orbital structures are a main cause of vertical retraction syndrome. The presence of specific unusual eye movement and MRI imaging may assist in diagnosis. When the eyelid lag was found since the early age, anomalous orbital structures were implied.

  7. Effect of duration and severity of migraine on retinal nerve fiber layer, ganglion cell layer, and choroidal thickness.

    PubMed

    Abdellatif, Mona K; Fouad, Mohamed M

    2018-03-01

    To investigate the factors in migraine that have the highest significance on retinal and choroidal layers' thickness. Ninety patients with migraine and 40 age-matched healthy participants were enrolled in this observational, cross-sectional study. After full ophthalmological examination, spectral domain-optical coherence tomography was done for all patients measuring the thickness of ganglion cell layer and retinal nerve fiber layer. Enhanced depth imaging technique was used to measure the choroidal thickness. There was significant thinning in the superior and inferior ganglion cell layers, all retinal nerve fiber layer quadrants, and all choroidal quadrants (except for the central subfield) in migraineurs compared to controls. The duration of migraine was significantly correlated with ganglion cell layer, retinal nerve fiber layer, and all choroidal quadrants, while the severity of migraine was significantly correlated with ganglion cell layer and retinal nerve fiber layer only. Multiregression analysis showed that the duration of migraine is the most important determinant factor of the superior retinal nerve fiber layer quadrant (β = -0.375, p = 0.001) and in all the choroidal quadrants (β = -0.531, -0.692, -0.503, -0.461, -0.564, respectively, p  < 0.001), while severity is the most important determinant factor of inferior, nasal, and temporal retinal nerve fiber layer quadrants (β = -0.256, -0.335, -0.308; p  = 0.036, 0.005, 0.009, respectively) and the inferior ganglion cell layer hemisphere (β = -0.377 and p = 0.001). Ganglion cell layer, retinal nerve fiber layer, and choroidal thickness are significantly thinner in patients with migraine. The severity of migraine has more significant influence in the thinning of ganglion cell layer and retinal nerve fiber layer, while the duration of the disease affected the choroidal thickness more.

  8. Is appendiceal CT scan overused for evaluating patients with right lower quadrant pain?

    PubMed

    Safran, D B; Pilati, D; Folz, E; Oller, D

    2001-05-01

    Reports citing excellent sensitivity, specificity, and predictive accuracy of focused appendiceal computed tomography (CT) and showing an overall reduction in resource use and nontherapeutic laparotomies have led to increasing use of that imaging modality. Diagnostic algorithms have begun to incorporate appendiceal CT for patients presenting to the emergency department with right lower quadrant pain. We present a series of 4 cases in which use of appendiceal CT ultimately led to increased cost, resource use, and complexity in patient care. The results of these cases support an argument against unbridled use of appendiceal CT scanning and reinforce the need for clinical evaluation by the operating surgeon before routine performance of appendiceal CT scan.

  9. Resistive anode image converter

    NASA Technical Reports Server (NTRS)

    Lampton, M. L.; Paresce, F. (Inventor)

    1976-01-01

    The invention of an apparatus for imaging soft X-ray and ultraviolet electromagnetic radiation and charged particles was described. The apparatus includes a pair of microchannel electron multiplier plates connected in a cascaded chevron configuration which intercepts an incident beam of radiation or charged particles. Incident photons or charged particles strike the front surface of the chevron configuration causing emission of electrons. The electrons are accelerated by a voltage gradient and strike the inner side walls of the individual channels, causing emission of secondary electrons. Accelerated and multiplied secondary electrons impinge upon a resistive anode after they transverse the chevron configuration. A pulse position circuit converts the magnitude or transit time of the currents flowing from the point of impact of the electrons on the resistive anode to four contact electrodes mounted on their periphery of the resistive anode into the spatial coordinates of electron impact.

  10. Assessment of Different Sampling Methods for Measuring and Representing Macular Cone Density Using Flood-Illuminated Adaptive Optics.

    PubMed

    Feng, Shu; Gale, Michael J; Fay, Jonathan D; Faridi, Ambar; Titus, Hope E; Garg, Anupam K; Michaels, Keith V; Erker, Laura R; Peters, Dawn; Smith, Travis B; Pennesi, Mark E

    2015-09-01

    To describe a standardized flood-illuminated adaptive optics (AO) imaging protocol suitable for the clinical setting and to assess sampling methods for measuring cone density. Cone density was calculated following three measurement protocols: 50 × 50-μm sampling window values every 0.5° along the horizontal and vertical meridians (fixed-interval method), the mean density of expanding 0.5°-wide arcuate areas in the nasal, temporal, superior, and inferior quadrants (arcuate mean method), and the peak cone density of a 50 × 50-μm sampling window within expanding arcuate areas near the meridian (peak density method). Repeated imaging was performed in nine subjects to determine intersession repeatability of cone density. Cone density montages could be created for 67 of the 74 subjects. Image quality was determined to be adequate for automated cone counting for 35 (52%) of the 67 subjects. We found that cone density varied with different sampling methods and regions tested. In the nasal and temporal quadrants, peak density most closely resembled histological data, whereas the arcuate mean and fixed-interval methods tended to underestimate the density compared with histological data. However, in the inferior and superior quadrants, arcuate mean and fixed-interval methods most closely matched histological data, whereas the peak density method overestimated cone density compared with histological data. Intersession repeatability testing showed that repeatability was greatest when sampling by arcuate mean and lowest when sampling by fixed interval. We show that different methods of sampling can significantly affect cone density measurements. Therefore, care must be taken when interpreting cone density results, even in a normal population.

  11. Assessment of Different Sampling Methods for Measuring and Representing Macular Cone Density Using Flood-Illuminated Adaptive Optics

    PubMed Central

    Feng, Shu; Gale, Michael J.; Fay, Jonathan D.; Faridi, Ambar; Titus, Hope E.; Garg, Anupam K.; Michaels, Keith V.; Erker, Laura R.; Peters, Dawn; Smith, Travis B.; Pennesi, Mark E.

    2015-01-01

    Purpose To describe a standardized flood-illuminated adaptive optics (AO) imaging protocol suitable for the clinical setting and to assess sampling methods for measuring cone density. Methods Cone density was calculated following three measurement protocols: 50 × 50-μm sampling window values every 0.5° along the horizontal and vertical meridians (fixed-interval method), the mean density of expanding 0.5°-wide arcuate areas in the nasal, temporal, superior, and inferior quadrants (arcuate mean method), and the peak cone density of a 50 × 50-μm sampling window within expanding arcuate areas near the meridian (peak density method). Repeated imaging was performed in nine subjects to determine intersession repeatability of cone density. Results Cone density montages could be created for 67 of the 74 subjects. Image quality was determined to be adequate for automated cone counting for 35 (52%) of the 67 subjects. We found that cone density varied with different sampling methods and regions tested. In the nasal and temporal quadrants, peak density most closely resembled histological data, whereas the arcuate mean and fixed-interval methods tended to underestimate the density compared with histological data. However, in the inferior and superior quadrants, arcuate mean and fixed-interval methods most closely matched histological data, whereas the peak density method overestimated cone density compared with histological data. Intersession repeatability testing showed that repeatability was greatest when sampling by arcuate mean and lowest when sampling by fixed interval. Conclusions We show that different methods of sampling can significantly affect cone density measurements. Therefore, care must be taken when interpreting cone density results, even in a normal population. PMID:26325414

  12. Astronomical Near-neighbor Detection with a Four-quadrant Phase Mask (FQPM) Coronagraph

    NASA Technical Reports Server (NTRS)

    Haguenauer, Pierre; Serabyn, Eugene; Mennesson, Bertrand; Wallace, James K.; Gappinger, Robert O.; Troy, Mitchell; Bloemhof, Eric E.; Moore, Jim; Koresko, Chris D.

    2006-01-01

    Direct detection of planets around nearby stars requires the development of high-contrast imaging techniques, because of their very different respective fluxes. We thus investigated the innovative coronagraphic approach based on the use of a four-quadrant phase mask (FQPM). Simulations showed that, combined with high-level wavefront correction on an unobscured off-axis section of a large telescope, this method allows high-contrast imaging very close to stars, with detection capability superior to that of a traditional coronagraph. A FQPM instrument was thus built to test the feasibility of near-neighbor observations with our new off-axis approach on a ground-based telescope. In June 2005, we deployed our instrument to the Palomar 200-inch telescope, using existing facilities as much as possible for rapid implementation. In these initial observations, using data processing techniques specific to FQPM coronagraphs, we reached extinction levels of the order of 200:1. Here we discuss our simulations and on-sky results obtained so far.

  13. Multiparameter double hole contrast detail phantom: Ability to detect image displacement due to off position anode stem

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pauzi, Nur Farahana; Majid, Zafri Azran Abdul; Sapuan, Abdul Halim

    Contrast Detail phantom is a quality control tool to analyze the performance of imaging devices. Currently, its function is solely to evaluate the contrast detail characteristic of imaging system. It consists of drilled hole which gives effect to the penetration of x-ray beam divergence to pass through the base of each hole. This effect will lead to false appearance of image from its original location but it does not being visualized in the radiograph. In this study, a new design of Contrast Detail phantom’s hole which consists of double hole construction has been developed. It can detect the image displacementmore » which is due to off position of anode stem from its original location. The double hole differs from previous milled hole, whereby it consists of combination of different hole diameters. Small hole diameter (3 mm) is positioned on top of larger hole diameter (10 mm). The thickness of double hole acrylic blocks is 13 mm. Result revealed that Multiparameter Double Hole Contrast Detail phantom can visualize the shifted flaw image quality produced by x-ray machine due to improper position of the anode stem which is attached to rotor and stator. The effective focal spot of x-ray beam also has been shifted from the center of collimator as a result of off-position anode stem. As a conclusion, the new design of double hole Contrast Detail phantom able to measure those parameters in a well manner.« less

  14. Contrast-to-noise ratio in magnification mammography: a Monte Carlo study

    NASA Astrophysics Data System (ADS)

    Koutalonis, M.; Delis, H.; Spyrou, G.; Costaridou, L.; Tzanakos, G.; Panayiotakis, G.

    2007-06-01

    Magnification views are a common way to perform a secondary examination when suspicious abnormalities are found in a screening mammogram. The visibility of microcalcifications and breast lesions is restricted by the compromise between the image quality and the absorbed dose. In this study, image quality characteristics in magnification mammography were evaluated based on Monte Carlo techniques. A breast phantom was utilized, simulating a homogeneous mixture of adipose and glandular tissue in various percentages of glandularity, containing inhomogeneities of various sizes and compositions. The effect of the magnification degree, breast glandularity, tube voltage and anode/filter material combination on image quality characteristics was investigated in terms of a contrast-to-noise ratio (CNR). A performance index PIν was introduced in order to study the overall performance of various anode/filter combinations under different exposure parameters. Results demonstrate that CNR is improved with the degree of magnification and degraded as the breast glandularity is increased. Degree of magnification 1.3 offers the best overall performance for most of the anode/filter combinations utilized. Under magnification conditions, the role of dose is demoted against the image quality, as magnification views are secondary, diagnostic examinations and not screening procedures oriented to non-symptomatic women. For decreased image quality weighting, some anode/filter combinations different from Mo/0.030mmMo can be utilized as they offer a similar performance index. However, if the desired weighting for the image quality is high, the Mo/0.030mmMo combination has the best overall performance.

  15. A correction method of the anode wire modulation for 2D MWPCs detector

    NASA Astrophysics Data System (ADS)

    Wen, Z. W.; Qi, H. R.; Zhang, Y. L.; Wang, H. Y.; Liu, L.; Li, Y. H.

    2018-04-01

    The linearity performance of 2D Multi-Wire Proportional Chambers (MWPCs) detector across the anode wires is modulated by the discrete anode wires. A MWPCs dectector with the 2 mm anode wire spacing was developed to study the anode wire modulation effect. The 2D lineartity performance was measured with a 55Fe source which was moved by a electric mobile platform. The experimental results show that the deviation of the measured position depends upon the incident position in the axis across the anode wires and the curve between the measured position and the incident position is consistent with the sine function whose period is equal to the anode wire spacing. A correction method of the measured position across the anode wire direction was obtained by fitting the curve between the measured position and the incident position. The non-linearity of the measured position across the anode wire direction is reduced about 0.085% and the imaging capability is obviously improved after the data is modified by the correction method.

  16. Analysis of nanopore arrangement of porous alumina layers formed by anodizing in oxalic acid at relatively high temperatures

    NASA Astrophysics Data System (ADS)

    Zaraska, Leszek; Stępniowski, Wojciech J.; Jaskuła, Marian; Sulka, Grzegorz D.

    2014-06-01

    Anodic aluminum oxide (AAO) layers were formed by a simple two-step anodization in 0.3 M oxalic acid at relatively high temperatures (20-30 °C) and various anodizing potentials (30-65 V). The effect of anodizing conditions on structural features of as-obtained oxides was carefully investigated. A linear and exponential relationships between cell diameter, pore density and anodizing potential were confirmed, respectively. On the other hand, no effect of temperature and duration of anodization on pore spacing and pore density was found. Detailed quantitative and qualitative analyses of hexagonal arrangement of nanopore arrays were performed for all studied samples. The nanopore arrangement was evaluated using various methods based on the fast Fourier transform (FFT) images, Delaunay triangulations (defect maps), pair distribution functions (PDF), and angular distribution functions (ADF). It was found that for short anodizations performed at relatively high temperatures, the optimal anodizing potential that results in formation of nanostructures with the highest degree of pore order is 45 V. No direct effect of temperature and time of anodization on the nanopore arrangement was observed.

  17. Effects of anode geometry on forward wide-angle neon ion emissions in 3.5 kJ plasma focus device by novel mega-size panorama polycarbonate image detectors

    NASA Astrophysics Data System (ADS)

    Sohrabi, M.; Soltani, Z.; Sarlak, Z.

    2018-03-01

    Forward wide-angle neon ion emissions in a 3.5 kJ plasma focus device (PFD) were studied using 5 different anode top geometries; hollow-end cylinder, solid triangle, solid hemisphere, hollow-end cone and flat-end cone. Position-sensitive mega-size panorama polycarbonate ion image detectors (MS-PCID) developed by dual-cell circular mega-size electrochemical etching (MS-ECE) systems were applied for processesing wide-angle neon ion images on MS-PCIDs exposed on the PFD cylinder top base under a single pinch shot. The images can be simply observed, analyzed and relatively quantified in terms of ion emission angular distributions even by the unaided eyes. By analysis of the forward neon ion emission images, the ion emission yields, ion emission angular distributions, iso-fluence ion contours and solid angles of ion emissions in 4π PFD space were determined. The neon ion emission yields on the PFD cylinder top base are in an increasing order ~2.1×109, ~2.2 ×109, ~2.8×109, ~2.9×109, and ~3.5×109 neon ions/shot for the 5 stated anode top geometries respectively. The panorama neon ion images as diagnosed even by the unaided eyes demonstrate the lowest and highest ion yields from the hollow-end cylinder and flat-end cone anode tops respectively. Relative dynamic qualitative neon ion spectrometry was made by the unaided eyes demonstrating relative neon ion energy as they appear. The study also demonstrates the unique power of the MS-PCID/MS-ECE imaging system as an advanced state-of-the-art ion imaging method for wide-angle dynamic parametric studies in PFD space and other ion study applications.

  18. Process for thermal imaging scanning of a swaged heater for an anode subassembly of a hollow cathode assembly

    NASA Technical Reports Server (NTRS)

    Patterson, Michael J. (Inventor); Verhey, Timothy R. R. (Inventor); Soulas, George C. (Inventor)

    2004-01-01

    A process for thermal imaging scanning of a swaged heater of an anode subassembly of a hollow cathode assembly, comprising scanning a swaged heater with a thermal imaging radiometer to measure a temperature distribution of the heater; raising the current in a power supply to increase the temperature of the swaged heater; and measuring the swaged heater temperature using the radiometer, whereupon the temperature distribution along the length of the heater shall be less than plus or minus 5 degrees C.

  19. Regional odontodysplasia involving three quadrants of the jaws: a case report.

    PubMed

    Quinderé, Lêda Bezerra; Cavalcante, Roberta Barroso; Nonaka, Cassiano Francisco Weege; Miguel, Márcia Cristina da Costa; de Souza, Lélia Batista

    2010-01-01

    Regional odontodysplasia is a rare developmental anomaly of the teeth that affects enamel and dentin. Its etiology is unknown, but the most accepted theory refers to circulatory disorders associated with vascular nevi. An uncommon case of regional odontodysplasia involving three quadrants of the jaws is reported. An 8-year-old boy was referred to the authors' institution with lack of teeth as a major symptom. There was no hereditary anomaly in the family. Extraoral examination revealed a brown discoloration on the skin on the right side of the face, neck, and chest. Detailed intraoral examination showed hypoplastic and carious teeth. Fistulae and gingival overgrowth were also observed. Radiographically, the affected teeth presented the pathognomonic image of "ghost teeth." Conservative treatment was instituted.

  20. A study of lip print pattern in Goan dental students - A digital approach.

    PubMed

    Prabhu, Rachana V; Dinkar, Ajit; Prabhu, Vishnudas

    2012-10-01

    To find the incidence of different types of lip patterns, the dominant pattern, quadrant wise, amongst the Goan population. To assess, the quadrant wise differences in lip patterns among males and females and to report new lip print pattern in Goan population. Lip prints of 100 students studying in Goa Dental College & Hospital were taken using 14 mm wide and 50 mm long Scotch tape without any distortion. These prints were then scanned (256 gray shades at a resolution of 300 dpi.) for the digital analysis. Using various applications of Adobe Photoshop 7 software an attempt was made to trace each and every line. K. Suzuki and Y. Tsuchihashi's classification was followed to define the patterns of the grooves. The current study has found the most predominant pattern in Quadrant I to be Type V (580 lines; 52.39%) followed in order by Type I' (196 lines; 17.70%), Type I (166 lines; 14.99%), Type II (166 lines; 10.47%), Type IV (40 lines; 3.61%), Type III (9 lines; 0.81%). In Quadrant II of this study the most predominant pattern recorded was Type V (589 lines; 50.47%) followed in order by Type I' (209 lines; 17.90%), Type I (204 lines; 17.48%), Type II (130 lines; 11.13%), Type IV (34 lines; 2.91%), Type III (1 line; 0.08%). In Quadrant III of this study the most predominant pattern recorded was again Type V (484 lines; 52.09%) followed in order by Type I' (174 lines; 18.72%), Type I (155 lines; 16.68%), Type II (102 lines; 10.97%), Type IV (9 lines; 0.96%), Type III (5 lines; 0.53%). In Quadrant IV of this study the most predominant pattern recorded was Type V (543 lines; 58.19%) followed in order by Type I (151 lines; 16.18%), Type I' (138 lines; 14.79%), Type II (85 lines; 9.11%), Type III (9 lines; 0.96%), Type IV (7 line; 0.75%). In all four Quadrants the most predominant pattern found in males and females was Type V. The present study recorded the following types of type V patterns for the first time; Trifurcations, Bridge or 'H' pattern, Horizontal Lines, Cartwheel, Pineapple Skin and Multiple Branching Appearance. The digital method of analyzing the Lip Print images using Adobe Photoshop 7 software serves as a convenient method that provides better visualization and ease in identification and recording of the Lip Print pattern. Predominant pattern in all four quadrants was Type V followed by the linear pattern i.e. Type I' in quadrants I, II, and III and Type I in quadrant IV in the studied population. Distribution of pattern is not affected by the sex. Although type V is the most predominant pattern found in Goan population, the sub-classification of this type defines the more defined term and aids in accuracy of the classification. Copyright © 2012. Published by Elsevier Ltd.

  1. Dependence of CO2 Reactivity of Carbon Anodes on Pore Structure

    NASA Astrophysics Data System (ADS)

    Chen, Tong; Xue, Jilai; Lang, Guanghui; Liu, Rui; Gao, Shoulei; Wang, Zengjie

    2017-09-01

    The correlation between the CO2 reactivity and pore structure of carbon anodes was experimentally investigated. The pore structures of the anodes before and after CO2 oxidation were characterized using image analysis. The porosity, mean pore diameter, and the number of micro-cracks decreased with increasing anode forming pressure, while they increased with over-compaction. With prolonged CO2 oxidation time, the porosity, pore density, mean pore diameter, pore aspect ratio, and the number of micro-cracks increased due to the merging of small pores, increased pore connectivity, and generation of new pores. The activation energy decreased with increasing porosity of the anodes' pitch phase due to easier CO2 penetration and reaction within the anodes. The results confirm that the fine pitch-coke phase of anodes is preferentially consumed, a cause of carbon dusting. Optimization of the pore structures to balance the pitch, coke, and butt phases may potentially further reduce carbon dusting.

  2. In situ, simultaneous thermal imaging and infrared molecular emission studies of solid oxide fuel cell electrodes

    NASA Astrophysics Data System (ADS)

    Kirtley, J. D.; Qadri, S. N.; Steinhurst, D. A.; Owrutsky, J. C.

    2016-12-01

    Various in situ probes of solid oxide fuel cells (SOFCs) have advanced recently to provide detailed, real time data regarding materials and chemical processes that relate to device performance and degradation. These techniques offer insights into complex fuel chemistry at the anode in particular, especially in the context of model predictions. However, cell-to-cell variations can hinder mechanistic interpretations of measurements from separate, independent techniques. The present study describes an in situ technique that for the first time simultaneously measures surface temperature changes using near infrared thermal imaging and gas species using Fourier-transform infrared emission spectra at the anodes of operating SOFCs. Electrolyte-supported SOFCs with Ni-based anodes are operated at 700 °C with internal, dry-reformed methane at 75% maximum current and at open circuit voltage (OCV) while electrochemical and optical measurements are collected. At OCV, more cooling is observed coincident with more CO reforming products. Under load, CO decreases while the anode cools less, especially near the current collectors. The extent of cooling is more sensitive to polarization for electrolyte-supported cells because their anodes are thinner relative to anode-supported cells. This study exemplifies how this duplex technique can be a useful probe of electrochemical processes in SOFCs.

  3. X-ray source for mammography

    DOEpatents

    Logan, Clinton M.

    1994-01-01

    An x-ray source utilizing anode material which shifts the output spectrum to higher energy and thereby obtains higher penetrating ability for screening mammography application, than the currently utilized anode material. The currently used anode material (molybdenum) produces an energy x-ray spectrum of 17.5/19.6 keV, which using the anode material of this invention (e.g. silver, rhodium, and tungsten) the x-ray spectrum would be in the 20-35 keV region. Thus, the anode material of this invention provides for imaging of breasts with higher than average x-ray opacity without increase of the radiation dose, and thus reduces the risk of induced breast cancer due to the radiation dose administered for mammograms.

  4. Automated analysis of angle closure from anterior chamber angle images.

    PubMed

    Baskaran, Mani; Cheng, Jun; Perera, Shamira A; Tun, Tin A; Liu, Jiang; Aung, Tin

    2014-10-21

    To evaluate a novel software capable of automatically grading angle closure on EyeCam angle images in comparison with manual grading of images, with gonioscopy as the reference standard. In this hospital-based, prospective study, subjects underwent gonioscopy by a single observer, and EyeCam imaging by a different operator. The anterior chamber angle in a quadrant was classified as closed if the posterior trabecular meshwork could not be seen. An eye was classified as having angle closure if there were two or more quadrants of closure. Automated grading of the angle images was performed using customized software. Agreement between the methods was ascertained by κ statistic and comparison of area under receiver operating characteristic curves (AUC). One hundred forty subjects (140 eyes) were included, most of whom were Chinese (102/140, 72.9%) and women (72/140, 51.5%). Angle closure was detected in 61 eyes (43.6%) with gonioscopy in comparison with 59 eyes (42.1%, P = 0.73) using manual grading, and 67 eyes (47.9%, P = 0.24) with automated grading of EyeCam images. The agreement for angle closure diagnosis between gonioscopy and both manual (κ = 0.88; 95% confidence interval [CI), 0.81-0.96) and automated grading of EyeCam images was good (κ = 0.74; 95% CI, 0.63-0.85). The AUC for detecting eyes with gonioscopic angle closure was comparable for manual and automated grading (AUC 0.974 vs. 0.954, P = 0.31) of EyeCam images. Customized software for automated grading of EyeCam angle images was found to have good agreement with gonioscopy. Human observation of the EyeCam images may still be needed to avoid gross misclassification, especially in eyes with extensive angle closure. Copyright 2014 The Association for Research in Vision and Ophthalmology, Inc.

  5. Doped carbon nanostructure field emitter arrays for infrared imaging

    DOEpatents

    Korsah, Kofi [Knoxville, TN; Baylor, Larry R [Farragut, TN; Caughman, John B [Oak Ridge, TN; Kisner, Roger A [Knoxville, TN; Rack, Philip D [Knoxville, TN; Ivanov, Ilia N [Knoxville, TN

    2009-10-27

    An infrared imaging device and method for making infrared detector(s) having at least one anode, at least one cathode with a substrate electrically connected to a plurality of doped carbon nanostructures; and bias circuitry for applying an electric field between the anode and the cathode such that when infrared photons are adsorbed by the nanostructures the emitted field current is modulated. The detectors can be doped with cesium to lower the work function.

  6. Properties of nanostructures obtained by anodization of aluminum in phosphoric acid at moderate potentials

    NASA Astrophysics Data System (ADS)

    Zaraska, L.; Sulka, G. D.; Jaskuła, M.

    2009-01-01

    The influence of the process duration, anodizing potential and methanol addition on the structural features of porous anodic alumina formed in a 0.3 M H3PO4 solutions by twostep self-organized anodizing was investigated for potentials ranging from 100 to 170 V. The structural features of porous structures including pore diameter and interpore distance were evaluated from FE-SEM top-view images for samples anodized in the presence and absence of methanol. For the highest studied anodizing time and methanol volume fraction, an excellent agreement between experimental values of the interpore distance and theoretical predictions was observed. The pore arrangement regularity was analyzed for various electrolyte compositions and anodizing potentials. It was found that the regularity ratio of porous alumina increases linearly with increasing anodizing potential and time. The addition of methanol improves the quality of nanostructures and especially better uniformity of pore sizes is observed in the presence of the highest studied methanol content.

  7. Evaluation of the association between quantitative mammographic density and breast cancer occurred in different quadrants.

    PubMed

    Chan, Siwa; Chen, Jeon-Hor; Li, Shunshan; Chang, Rita; Yeh, Darh-Cherng; Chang, Ruey-Feng; Yeh, Lee-Ren; Kwong, Jessica; Su, Min-Ying

    2017-04-17

    To investigate the relationship between mammographic density measured in four quadrants of a breast with the location of the occurred cancer. One hundred and ten women diagnosed with unilateral breast cancer that could be determined in one specific breast quadrant were retrospectively studied. Women with previous cancer/breast surgery were excluded. The craniocaudal (CC) and mediolateral oblique (MLO) mammography of the contralateral normal breast were used to separate a breast into 4 quadrants: Upper-Outer (UO), Upper-Inner (UI), Lower-Outer (LO), and Lower-Inner (LI). The breast area (BA), dense area (DA), and percent density (PD) in each quadrant were measured by using the fuzzy-C-means segmentation. The BA, DA, and PD were compared between patients who had cancer occurring in different quadrants. The upper-outer quadrant had the highest BA (37 ± 15 cm 2 ) and DA (7.1 ± 2.9 cm 2 ), with PD = 20.0 ± 5.8%. The order of BA and DA in the 4 separated quadrants were: UO > UI > LO > LI, and almost all pair-wise comparisons showed significant differences. For tumor location, 67 women (60.9%) had tumor in UO, 16 (14.5%) in UI, 7 (6.4%) in LO, and 20 (18.2%) in LI quadrant, respectively. The estimated odds and the 95% confidence limits of tumor development in the UO, UI, LO and LI quadrants were 1.56 (1.06, 2.29), 0.17 (0.10, 0.29), 0.07 (0.03, 0.15), and 0.22 (0.14, 0.36), respectively. In these 4 groups of women, the order of quadrant BA and DA were all the same (UO > UI > LO > LI), and there was no significant difference in BA, DA or PD among them (all p > 0.05). Breast cancer was most likely to occur in the UO quadrant, which was also the quadrant with highest BA and DA; but for women with tumors in other quadrants, the density in that quadrant was not the highest. Therefore, there was no direct association between quadrant density and tumor occurrence.

  8. Focal spot size reduction using asymmetric collimation to enable reduced anode angles with a conventional angiographic x-ray tube for use with high resolution detectors.

    PubMed

    Russ, M; Shankar, A; Setlur Nagesh, S V; Ionita, C N; Bednarek, D R; Rudin, S

    2017-02-11

    The high-resolution requirements for neuro-endovascular image-guided interventions (EIGIs) necessitate the use of a small focal-spot size; however, the maximum tube output limits for such small focal-spot sizes may not enable sufficient x-ray fluence after attenuation through the human head to support the desired image quality. This may necessitate the use of a larger focal spot, thus contributing to the overall reduction in resolution. A method for creating a higher-output small effective focal spot based on the line-focus principle has been demonstrated and characterized. By tilting the C-arm gantry, the anode-side of the x-ray field-of-view is accessible using a detector placed off-axis. This tilted central axis diminishes the resultant focal spot size in the anode-cathode direction by the tangent of the effective anode angle, allowing a medium focal spot to be used in place of a small focal spot with minimal losses in resolution but with increased tube output. Images were acquired of two different objects at the central axis, and with the C-arm tilted away from the central axis at 1° increments from 0°-7°. With standard collimation settings, only 6° was accessible, but using asymmetric extended collimation a maximum of 7° was accessed for enhanced comparisons. All objects were positioned perpendicular to the anode-cathode direction and images were compared qualitatively. The increasing advantage of the off-axis focal spots was quantitatively evidenced at each subsequent angle using the Generalized Measured-Relative Object Detectability metric (GM-ROD). This anode-tilt method is a simple and robust way of increasing tube output for a small field-of-view detector without diminishing the overall apparent resolution for neuro-EIGIs.

  9. Focal spot size reduction using asymmetric collimation to enable reduced anode angles with a conventional angiographic x-ray tube for use with high resolution detectors

    NASA Astrophysics Data System (ADS)

    Russ, M.; Shankar, A.; Setlur Nagesh, S. V.; Ionita, C. N.; Bednarek, D. R.; Rudin, S.

    2017-03-01

    The high-resolution requirements for neuro-endovascular image-guided interventions (EIGIs) necessitate the use of a small focal-spot size; however, the maximum tube output limits for such small focal-spot sizes may not enable sufficient x-ray fluence after attenuation through the human head to support the desired image quality. This may necessitate the use of a larger focal spot, thus contributing to the overall reduction in resolution. A method for creating a higher-output small effective focal spot based on the line-focus principle has been demonstrated and characterized. By tilting the C-arm gantry, the anode-side of the x-ray field-of-view is accessible using a detector placed off-axis. This tilted central axis diminishes the resultant focal spot size in the anode-cathode direction by the tangent of the effective anode angle, allowing a medium focal spot to be used in place of a small focal spot with minimal losses in resolution but with increased tube output. Images were acquired of two different objects at the central axis, and with the C-arm tilted away from the central axis at 1° increments from 0°-7°. With standard collimation settings, only 6° was accessible, but using asymmetric extended collimation a maximum of 7° was accessed for enhanced comparisons. All objects were positioned perpendicular to the anode-cathode direction and images were compared qualitatively. The increasing advantage of the off-axis focal spots was quantitatively evidenced at each subsequent angle using the Generalized Measured-Relative Object Detectability metric (GM-ROD). This anode-tilt method is a simple and robust way of increasing tube output for a small field-of-view detector without diminishing the overall apparent resolution for neuro-EIGIs.

  10. Clinical use of MRI for the evaluation of acute appendicitis during pregnancy.

    PubMed

    Patel, Darshan; Fingard, Jordan; Winters, Sean; Low, Gavin

    2017-07-01

    The purpose of this study was to determine the diagnostic accuracy of MRI for detecting acute appendicitis in pregnancy in a multi-institution study involving general body MR readers with no specific expertise in MR imaging of the pregnant patient. Retrospective review of MRI examinations on PACS in 42 pregnant patients was evaluated for acute right lower quadrant pain. Three fellowship-trained general body radiologists analyzed the MRI examinations in consensus and attempted to localize the appendix, assess for features of appendicitis, and exclude alternative etiologies for the right lower quadrant pain. Of the 42 MRI examinations, the readers noted 6 cases of acute appendicitis, 16 cases of a normal appendix, and 20 cases involving non-visualization of the appendix but where there were no secondary features of acute appendicitis. Based on the surgical data and clinical follow-up, there were 3 true-positive cases, 3 false-positive cases, 34 true-negative cases, and 2 false-negative cases of acute appendicitis on MRI. This yielded an accuracy of 88.1%, sensitivity of 60%, specificity of 91.9%, positive predictive value of 50%, and negative predictive value of 94.4% for the detection of acute appendicitis in the pregnant patient on MRI. Alternative etiologies for the right lower quadrant pain on MRI included torsion of an ovarian dermoid in 1 case and pyelonephritis in 1 case. MRI is an excellent modality for excluding acute appendicitis in pregnant patients presenting with right lower quadrant pain.

  11. Improved cell for water-vapor electrolysis

    NASA Technical Reports Server (NTRS)

    Aylward, J. R.

    1981-01-01

    Continuous-flow electrolytic cells decompose water vapor in steam and room air into hydrogen and oxygen. Sintered iridium oxide catalytic anode coating yields dissociation rates hundredfold greater than those obtained using platinum black. Cell consists of two mirror-image cells, with dual cathode sandwiched between two anodes. Gas traverses serpentine channels within cell and is dissociated at anode. Oxygen mingles with gas stream, while hydrogen migrates through porous matrix and is liberated as gas at cathode.

  12. Processing Ti-25Ta-5Zr Bioalloy via Anodic Oxidation Procedure at High Voltage

    NASA Astrophysics Data System (ADS)

    Ionita, Daniela; Grecu, Mihaela; Dilea, Mirela; Cojocaru, Vasile Danut; Demetrescu, Ioana

    2011-12-01

    The current paper reports the processing of Ti-25Ta-5Zr bioalloy via anodic oxidation in NH4BF4 solution under constant potentiostatic conditions at high voltage to obtain more suitable properties for biomedical application. The maximum efficiency of the procedure is reached at highest applied voltage, when the corrosion rate in Hank's solution is decreased approxomately six times. The topography of the anodic layer has been studied using atomic force microscopy (AFM), and the results indicated that the anodic oxidation process increases the surface roughness. The AFM images indicated a different porosity for the anodized surfaces as well. After anodizing, the hydrophilic character of Ti-25Ta-5Zr samples has increased. A good correlation between corrosion rate obtained from potentiodynamic curves and corrosion rate from ions release analysis was obtained.

  13. X-ray source for mammography

    DOEpatents

    Logan, C.M.

    1994-12-20

    An x-ray source is described utilizing anode material which shifts the output spectrum to higher energy and thereby obtains higher penetrating ability for screening mammography application, than the currently utilized anode material. The currently used anode material (molybdenum) produces an energy x-ray spectrum of 17.5/19.6 keV, which using the anode material of this invention (e.g. silver, rhodium, and tungsten) the x-ray spectrum would be in the 20-35 keV region. Thus, the anode material of this invention provides for imaging of breasts with higher than average x-ray opacity without increase of the radiation dose, and thus reduces the risk of induced breast cancer due to the radiation dose administered for mammograms. 6 figures.

  14. Duodenal Obstruction Caused by Acute Appendicitis with Intestinal Malrotation in a Child.

    PubMed

    Biçer, Şenol; Çelik, Ali

    2015-08-27

    In patients with intestinal malrotation, the diagnosis of acute appendicitis can be difficult due to atypical presentation. Duodenal obstruction caused by acute appendicitis with the presence of malrotation has rarely been reported in children. We report the case of a 14-year-old male patient with bilious vomiting and abdominal distension. A diagnosis could not be made by computed tomography, ultrasonography, or endoscopy. We observed a dilated stomach and malrotation in laparotomy. The caecum was in the right upper quadrant, and an inflamed appendix was located in the subhepatic region. After the appendectomy, the cecum was mobilized and fixed in the right lower quadrant. In children with intestinal malrotation, acute appendicitis can present as duodenal obstruction without abdominal pain, and standard imaging methods can miss the correct diagnosis.

  15. White Light Sagnac Interferometer for Snapshot Multispectral Imaging (Preprint)

    DTIC Science & Technology

    2009-01-01

    normalized difference vegetation index ( NDVI ) provided in Fig. 12 (b). The NDVI is calculated by ( ) ( ) ( )( ) ( ) , ,2 , ,3 , , ,2 , ,3 I l n I l n NDVI ... NDVI . Conversely, if the leaf has little to no chlorophyll, order 3 will have nearly equal reflected energy compared to order 2, yielding a low NDVI ...This is observed in the NDVI image, where the upper left portion of the scene (quadrant 2) contains the unhealthy leaf, while the lower right region

  16. Hurricane Hector in the Eastern Pacific

    NASA Image and Video Library

    2006-08-17

    Infrared, microwave, and visible/near-infrared images of Hurricane Hector in the eastern Pacific were created with data from the Atmospheric Infrared Sounder (AIRS) on NASA's Aqua satellite on August 17, 2006. The infrared AIRS image shows the temperature of the cloud tops or the surface of the Earth in cloud-free regions. The lowest temperatures (in purple) are associated with high, cold cloud tops that make up the top of the hurricane. The infrared signal does not penetrate through clouds. Where there are no clouds the AIRS instrument reads the infrared signal from the surface of the Earth, revealing warmer temperatures (red). At the time the data were taken from which these images were made, Hector is a well organized storm, with the strongest convection in the SE quadrant. The increasing vertical wind shear in the NW quadrant is appearing to have an effect. Maximum sustained winds are at 85 kt, gusts to 105 kt. Estimated minimum central pressure is 975 mbar. The microwave image is created from microwave radiation emitted by Earth's atmosphere and received by the instrument. It shows where the heaviest rainfall is taking place (in blue) in the storm. Blue areas outside of the storm where there are either some clouds or no clouds, indicate where the sea surface shines through. The "visible" image is created from data acquired by the visible light/near-infrared sensor on the AIRS instrument. http://photojournal.jpl.nasa.gov/catalog/PIA00507

  17. Partial Correlation-Based Retinotopically Organized Resting-State Functional Connectivity Within and Between Areas of the Visual Cortex Reflects More Than Cortical Distance

    PubMed Central

    Dawson, Debra Ann; Lam, Jack; Lewis, Lindsay B.; Carbonell, Felix; Mendola, Janine D.

    2016-01-01

    Abstract Numerous studies have demonstrated functional magnetic resonance imaging (fMRI)-based resting-state functional connectivity (RSFC) between cortical areas. Recent evidence suggests that synchronous fluctuations in blood oxygenation level-dependent fMRI reflect functional organization at a scale finer than that of visual areas. In this study, we investigated whether RSFCs within and between lower visual areas are retinotopically organized and whether retinotopically organized RSFC merely reflects cortical distance. Subjects underwent retinotopic mapping and separately resting-state fMRI. Visual areas V1, V2, and V3, were subdivided into regions of interest (ROIs) according to quadrants and visual field eccentricity. Functional connectivity (FC) was computed based on Pearson's linear correlation (correlation), and Pearson's linear partial correlation (correlation between two time courses after the time courses from all other regions in the network are regressed out). Within a quadrant, within visual areas, all correlation and nearly all partial correlation FC measures showed statistical significance. Consistently in V1, V2, and to a lesser extent in V3, correlation decreased with increasing eccentricity separation. Consistent with previously reported monkey anatomical connectivity, correlation/partial correlation values between regions from adjacent areas (V1-V2 and V2-V3) were higher than those between nonadjacent areas (V1-V3). Within a quadrant, partial correlation showed consistent significance between regions from two different areas with the same or adjacent eccentricities. Pairs of ROIs with similar eccentricity showed higher correlation/partial correlation than pairs distant in eccentricity. Between dorsal and ventral quadrants, partial correlation between common and adjacent eccentricity regions within a visual area showed statistical significance; this extended to more distant eccentricity regions in V1. Within and between quadrants, correlation decreased approximately linearly with increasing distances separating the tested ROIs. Partial correlation showed a more complex dependence on cortical distance: it decreased exponentially with increasing distance within a quadrant, but was best fit by a quadratic function between quadrants. We conclude that RSFCs within and between lower visual areas are retinotopically organized. Correlation-based FC is nonselectively high across lower visual areas, even between regions that do not share direct anatomical connections. The mechanisms likely involve network effects caused by the dense anatomical connectivity within this network and projections from higher visual areas. FC based on partial correlation, which minimizes network effects, follows expectations based on direct anatomical connections in the monkey visual cortex better than correlation. Last, partial correlation-based retinotopically organized RSFC reflects more than cortical distance effects. PMID:26415043

  18. Partial Correlation-Based Retinotopically Organized Resting-State Functional Connectivity Within and Between Areas of the Visual Cortex Reflects More Than Cortical Distance.

    PubMed

    Dawson, Debra Ann; Lam, Jack; Lewis, Lindsay B; Carbonell, Felix; Mendola, Janine D; Shmuel, Amir

    2016-02-01

    Numerous studies have demonstrated functional magnetic resonance imaging (fMRI)-based resting-state functional connectivity (RSFC) between cortical areas. Recent evidence suggests that synchronous fluctuations in blood oxygenation level-dependent fMRI reflect functional organization at a scale finer than that of visual areas. In this study, we investigated whether RSFCs within and between lower visual areas are retinotopically organized and whether retinotopically organized RSFC merely reflects cortical distance. Subjects underwent retinotopic mapping and separately resting-state fMRI. Visual areas V1, V2, and V3, were subdivided into regions of interest (ROIs) according to quadrants and visual field eccentricity. Functional connectivity (FC) was computed based on Pearson's linear correlation (correlation), and Pearson's linear partial correlation (correlation between two time courses after the time courses from all other regions in the network are regressed out). Within a quadrant, within visual areas, all correlation and nearly all partial correlation FC measures showed statistical significance. Consistently in V1, V2, and to a lesser extent in V3, correlation decreased with increasing eccentricity separation. Consistent with previously reported monkey anatomical connectivity, correlation/partial correlation values between regions from adjacent areas (V1-V2 and V2-V3) were higher than those between nonadjacent areas (V1-V3). Within a quadrant, partial correlation showed consistent significance between regions from two different areas with the same or adjacent eccentricities. Pairs of ROIs with similar eccentricity showed higher correlation/partial correlation than pairs distant in eccentricity. Between dorsal and ventral quadrants, partial correlation between common and adjacent eccentricity regions within a visual area showed statistical significance; this extended to more distant eccentricity regions in V1. Within and between quadrants, correlation decreased approximately linearly with increasing distances separating the tested ROIs. Partial correlation showed a more complex dependence on cortical distance: it decreased exponentially with increasing distance within a quadrant, but was best fit by a quadratic function between quadrants. We conclude that RSFCs within and between lower visual areas are retinotopically organized. Correlation-based FC is nonselectively high across lower visual areas, even between regions that do not share direct anatomical connections. The mechanisms likely involve network effects caused by the dense anatomical connectivity within this network and projections from higher visual areas. FC based on partial correlation, which minimizes network effects, follows expectations based on direct anatomical connections in the monkey visual cortex better than correlation. Last, partial correlation-based retinotopically organized RSFC reflects more than cortical distance effects.

  19. Accommodation-induced variations in retinal thickness measured by spectral domain optical coherence tomography

    NASA Astrophysics Data System (ADS)

    Fan, Shanhui; Sun, Yong; Dai, Cuixia; Zheng, Haihua; Ren, Qiushi; Jiao, Shuliang; Zhou, Chuanqing

    2014-09-01

    To research retinal stretching or distortion with accommodation, accommodation-induced changes in retinal thickness (RT) in the macular area were investigated in a population of young adults (n=23) by using a dual-channel spectral domain optical coherence tomography (SD-OCT) system manufactured in-house for this study. This dual-channel SD-OCT is capable of imaging the cornea and retina simultaneously with an imaging speed of 24 kHz A-line scan rate, which can provide the anatomical dimensions of the eye, including the RT and axial length. Thus, the modification of the RT with accommodation can be calculated. A significant decrease in the RT (13.50±1.25 μm) was observed during maximum accommodation. In the 4 mm×4 mm macular area centered at the fovea, we did not find a significant quadrant-dependent difference in retinal volume change, which indicates that neither retinal stretching nor distortion was quadrant-dependent during accommodation. We speculate that the changes in RT with maximum accommodation resulted from accommodation-induced ciliary muscle contractions.

  20. A novel concept for CT with fixed anodes (FACT): Medical imaging based on the feasibility of thermal load capacity.

    PubMed

    Kellermeier, Markus; Bert, Christoph; Müller, Reinhold G

    2015-07-01

    Focussing primarily on thermal load capacity, we describe the performance of a novel fixed anode CT (FACT) compared with a 100 kW reference CT. Being a fixed system, FACT has no focal spot blurring of the X-ray source during projection. Monte Carlo and finite element methods were used to determine the fluence proportional to thermal capacity. Studies of repeated short-time exposures showed that FACT could operate in pulsed mode for an unlimited period. A virtual model for FACT was constructed to analyse various temporal sequences for the X-ray source ring, representing a circular array of 1160 fixed anodes in the gantry. Assuming similar detector properties at a very small integration time, image quality was investigated using an image reconstruction library. Our model showed that approximately 60 gantry rounds per second, i.e. 60 sequential targetings of the 1160 anodes per second, were required to achieve a performance level equivalent to that of the reference CT (relative performance, RP = 1) at equivalent image quality. The optimal projection duration in each direction was about 10 μs. With a beam pause of 1 μs between projections, 78.4 gantry rounds per second with consecutive source activity were thermally possible at a given thermal focal spot. The settings allowed for a 1.3-fold (RP = 1.3) shorter scan time than conventional CT while maintaining radiation exposure and image quality. Based on the high number of rounds, FACT supports a high image frame rate at low doses, which would be beneficial in a wide range of diagnostic and technical applications. Copyright © 2015 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

  1. Digital quadrature phase detection

    DOEpatents

    Smith, James A.; Johnson, John A.

    1992-01-01

    A system for detecting the phase of a frequency of phase modulated signal that includes digital quadrature sampling of the frequency or phase modulated signal at two times that are one quarter of a cycle of a reference signal apart, determination of the arctangent of the ratio of a first sampling of the frequency or phase modulated signal to the second sampling of the frequency or phase modulated signal, and a determination of quadrant in which the phase determination is increased by 2.pi. when the quadrant changes from the first quadrant to the fourth quadrant and decreased by 2.pi. when the quadrant changes from the fourth quadrant to the first quadrant whereby the absolute phase of the frequency or phase modulated signal can be determined using an arbitrary reference convention.

  2. Digital quadrature phase detection

    DOEpatents

    Smith, J.A.; Johnson, J.A.

    1992-05-26

    A system for detecting the phase of a frequency or phase modulated signal that includes digital quadrature sampling of the frequency or phase modulated signal at two times that are one quarter of a cycle of a reference signal apart, determination of the arctangent of the ratio of a first sampling of the frequency or phase modulated signal to the second sampling of the frequency or phase modulated signal, and a determination of quadrant in which the phase determination is increased by 2[pi] when the quadrant changes from the first quadrant to the fourth quadrant and decreased by 2[pi] when the quadrant changes from the fourth quadrant to the first quadrant whereby the absolute phase of the frequency or phase modulated signal can be determined using an arbitrary reference convention. 6 figs.

  3. New insights into the initial stages of Ta oxide nanotube formation on polycrystalline Ta electrodes.

    PubMed

    El-Sayed, Hany A; Horwood, Corie A; Abhayawardhana, Anusha D; Birss, Viola I

    2013-02-21

    Ta oxide nanotubes (NTs) were formed by the anodization of Ta at 15 V in a solution of concentrated sulfuric acid containing 0.8-1.0 M hydrofluoric acid. To study the initial stages of NT formation, FESEM images of samples anodized for very short times were obtained. The results contradict the existing explanation of the current-time data collected during anodization, which has persisted in the literature for more than two decades. In addition to providing a first-time morphological study of Ta oxide NT formation at very early stages of anodization, we also propose a new interpretation of the i-t response, showing that pores are already present in the first few milliseconds of anodization and that NTs are formed well before present models predict. This behaviour may also extend to the anodization of other valve metals, such as Al, Ti, Zr, W, and Nb.

  4. In situ detection of porosity initiation during aluminum thin film anodizing

    NASA Astrophysics Data System (ADS)

    Van Overmeere, Quentin; Nysten, Bernard; Proost, Joris

    2009-02-01

    High-resolution curvature measurements have been performed in situ during aluminum thin film anodizing in sulfuric acid. A well-defined transition in the rate of internal stress-induced curvature change is shown to allow for the accurate, real-time detection of porosity initiation. The validity of this in situ diagnostic tool was confirmed by a quantitative analysis of the spectral density distributions of the anodized surfaces. These were obtained by analyzing ex situ atomic force microscopy images of surfaces anodized for different times, and allowed to correlate the in situ detected transition in the rate of curvature change with the appearance of porosity.

  5. Gangrenous Appendicitis in a Boy with Mobile Caecum.

    PubMed

    Keskin, Suat; Keskin, Zeynep; Gunduz, Metin; Sekmenli, Taner; Kivrak, Hatice Yazar

    2015-04-01

    A mobile caecum and ascending colon is an uncommon congenital disorder, and it is even rarer as the cause of an acute abdomen during childhood. This report presents the case of a 6-year-old boy with acute gangrenous appendicitis with a mobile caecum and ascending colon. Data from the surgical course, as well as laboratory and imaging studies, were acquired and carefully examined. Emergency ultrasound (US) was performed and revealed no signs of appendicitis in the right lower quadrant. Serial imaging study, including non-enhanced computed tomography (CT), was performed. An imaging study identified epigastric appendicitis with mobile caecum. Surgery was executed under general anesthesia with a median incision extending from the epigastrium to the suprapubic region. The caecum was mobile and placed in the right epigastric area, next to the left lobe of the liver and gallbladder. The gangrenous appendix was discovered posterior to the caecum and transverse colon, enlarging to the left upper quadrant. Appendectomy was executed, the gangrenous appendix was confirmed pathologically, and the patient was released 4 days later. In the US, if there are unusual clinical findings or no findings in patients with abdominal pain, CT is beneficial in determining the location of the caecum and appendix and preventing misdiagnosis in children.

  6. Agreement between gonioscopy and ultrasound biomicroscopy in detecting iridotrabecular apposition.

    PubMed

    Barkana, Yaniv; Dorairaj, Syril K; Gerber, Yariv; Liebmann, Jeffrey M; Ritch, Robert

    2007-10-01

    To assess the agreement between findings obtained at dark-room gonioscopy and ultrasound biomicroscopy (UBM) in the diagnosis of iridotrabecular apposition in light and dark conditions. We enrolled patients with appositional angle closure at dark-room gonioscopy performed using a 1-mm slitlamp beam that did not cross the pupil. Ultrasound biomicroscopic images were acquired in normal room light and subsequently with all room lights off. Images were evaluated for the presence or absence of iris-cornea contact. The angle opening distance at 500 microm was calculated. Iridotrabecular apposition in at least 1 angle quadrant was demonstrated in all 18 eyes at dark-room gonioscopy, 17 eyes (94%) at dark-room UBM, and only 10 eyes (56%) at UBM in room light. Of 18 superior angles that were appositionally closed at dark-room gonioscopy, apposition was demonstrated on UBM images in 16 (89%) in a dark room but only 6 (33%) in room light. Angle opening distance was less during dark-room gonioscopy in all but the nasal quadrant. We found high agreement between gonioscopy and UBM when both are performed in a completely dark room. Our findings support the recommendation that, in routine clinical practice, gonioscopy be performed in a dark room to avoid misdiagnosis of treatable iridotrabecular apposition.

  7. Analysis of nanopore arrangement and structural features of anodic alumina layers formed by two-step anodizing in oxalic acid using the dedicated executable software

    NASA Astrophysics Data System (ADS)

    Zaraska, Leszek; Stępniowski, Wojciech J.; Sulka, Grzegorz D.; Ciepiela, Eryk; Jaskuła, Marian

    2014-02-01

    Anodic porous alumina layers were fabricated by a two-step self-organized anodization in 0.3 M oxalic acid under various anodizing potentials ranging from 30 to 60 V at two different temperatures (10 and 17 ∘C). The effect of anodizing conditions on structural features and pore arrangement of AAO was investigated in detail by using the dedicated executable publication combined with ImageJ software. With increasing anodizing potential, a linear increase of the average pore diameter, interpore distance, wall thickness and barrier layer thickness, as well as a decrease of the pore density, were observed. In addition, the higher pore diameter and porosity values were obtained for samples anodized at the elevated temperature, independently of the anodizing potential. A degree of pore order was investigated on the basis of Delaunay triangulations (defect maps) and calculation of pair distribution or angle distribution functions (PDF or ADF), respectively. All methods confirmed that in order to obtain nanoporous alumina with the best, hexagonal pore arrangement, the potential of 40 V should be applied during anodization. It was confirmed that the dedicated executable publication can be used to a fast and complex analysis of nanopore arrangement and structural features of nanoporous oxide layers.

  8. Inspection of baked carbon anodes using a combination of multi-spectral acousto-ultrasonic techniques and principal component analysis.

    PubMed

    Boubaker, Moez Ben; Picard, Donald; Duchesne, Carl; Tessier, Jayson; Alamdari, Houshang; Fafard, Mario

    2018-05-17

    This paper reports on the application of an acousto-ultrasonic (AU) scheme for the inspection of industrial-size carbon anode blocks used in the production of primary aluminium by the Hall-Héroult process. A frequency-modulated wave is used to excite the anode blocks at multiple points. The collected attenuated AU signals are decomposed using the Discrete Wavelet Transform (DTW) after which vectors of features are calculated. Principal Component Analysis (PCA) is utilized to cluster the AU responses of the anodes. The approach allows locating cracks in the blocks and the AU features were found sensitive to crack severity. The results are validated using images collected after cutting some anodes. Copyright © 2018 Elsevier B.V. All rights reserved.

  9. Investigation of the Internal Electric Field in Cadmium Zinc Telluride Detectors Using the Pockels Effect and the Analysis of Charge Transients

    NASA Technical Reports Server (NTRS)

    Groza, Michael; Krawczynski, Henic; Garson, Alfred, III; Martin, Jerrad W.; Lee, Kuen; Li, Qiang; Beilicke, Matthias; Cui, Yunlong; Buliga, Vladimir; Guo, Mingsheng; hide

    2010-01-01

    The Pockels electro-optic effect can be used to investigate the internal electric field in cadmium zinc telluride (CZT) single crystals that are used to fabricate room temperature x and gamma radiation detectors. An agreement is found between the electric field mapping obtained from Pockels effect images and the measurements of charge transients generated by alpha particles. The Pockels effect images of a CZT detector along two mutually perpendicular directions are used to optimize the detector response in a dual anode configuration, a device in which the symmetry of the internal electric field with respect to the anode strips is of critical importance. The Pockels effect is also used to map the electric field in a CZT detector with dual anodes and an attempt is made to find a correlation with the simulated electric potential in such detectors. Finally, the stress-induced birefringence effects seen in the Pockels images are presented and discussed.

  10. Investigation of the internal electric field in cadmium zinc telluride detectors using the Pockels effect and the analysis of charge transients

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Groza, Michael; Cui Yunlong; Buliga, Vladimir

    2010-01-15

    The Pockels electro-optic effect can be used to investigate the internal electric field in cadmium zinc telluride (CZT) single crystals that are used to fabricate room temperature x and gamma radiation detectors. An agreement is found between the electric field mapping obtained from Pockels effect images and the measurements of charge transients generated by alpha particles. The Pockels effect images of a CZT detector along two mutually perpendicular directions are used to optimize the detector response in a dual anode configuration, a device in which the symmetry of the internal electric field with respect to the anode strips is ofmore » critical importance. The Pockels effect is also used to map the electric field in a CZT detector with dual anodes and an attempt is made to find a correlation with the simulated electric potential in such detectors. Finally, the stress-induced birefringence effects seen in the Pockels images are presented and discussed.« less

  11. Imaging characteristics of the Extreme Ultraviolet Explorer microchannel plate detectors

    NASA Technical Reports Server (NTRS)

    Vallerga, J. V.; Kaplan, G. C.; Siegmund, O. H. W.; Lampton, M.; Malina, R. F.

    1989-01-01

    The Extreme Ultraviolet Explorer (EUVE) satellite will conduct an all-sky survey over the wavelength range from 70 A to 760 A using four grazing-incidence telescopes and seven microchannel-plate (MCP) detectors. The imaging photon-counting MCP detectors have active areas of 19.6 cm2. Photon arrival position is determined using a wedge-and-strip anode and associated pulse-encoding electronics. The imaging characteristics of the EUVE flight detectors are presented including image distortion, flat-field response, and spatial differential nonlinearity. Also included is a detailed discussion of image distortions due to the detector mechanical assembly, the wedge-and-strip anode, and the electronics. Model predictions of these distortions are compared to preflight calibration images which show distortions less than 1.3 percent rms of the detector diameter of 50 mm before correction. The plans for correcting these residual detector image distortions to less than 0.1 percent rms are also presented.

  12. Polarization-based compensation of astigmatism.

    PubMed

    Chowdhury, Dola Roy; Bhattacharya, Kallol; Chakraborty, Ajay K; Ghosh, Raja

    2004-02-01

    One approach to aberration compensation of an imaging system is to introduce a suitable phase mask at the aperture plane of an imaging system. We utilize this principle for the compensation of astigmatism. A suitable polarization mask used on the aperture plane together with a polarizer-retarder combination at the input of the imaging system provides the compensating polarization-induced phase steps at different quadrants of the apertures masked by different polarizers. The aberrant phase can be considerably compensated by the proper choice of a polarization mask and suitable selection of the polarization parameters involved. The results presented here bear out our theoretical expectation.

  13. Characterization of Localized Filament Corrosion Products at the Anodic Head on a Model Mg-Zn-Zr Alloy Surface

    DOE PAGES

    Rossouw, David; Fu, Dong; Leonard, Donovan N.; ...

    2017-02-15

    In this study, localized filament corrosion products at the anodic head on a model Mg-1%Zn-0.4%Zr alloy surface were characterized by electron microscopy techniques of site-specific lamella prepared by focused ion beam milling. It is revealed that the anodic head propagates underneath a largely intact thin and dense MgO surface film and comprises dense aggregates of nano-crystalline MgO within a nano-porous Mg(OH) 2 network. In conclusion, the findings contribute new supportive direct imaging insight into the source of the enhanced H 2 evolution that accompanies anodic dissolution of Mg and its alloys.

  14. Characterization of Localized Filament Corrosion Products at the Anodic Head on a Model Mg-Zn-Zr Alloy Surface

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rossouw, David; Fu, Dong; Leonard, Donovan N.

    In this study, localized filament corrosion products at the anodic head on a model Mg-1%Zn-0.4%Zr alloy surface were characterized by electron microscopy techniques of site-specific lamella prepared by focused ion beam milling. It is revealed that the anodic head propagates underneath a largely intact thin and dense MgO surface film and comprises dense aggregates of nano-crystalline MgO within a nano-porous Mg(OH) 2 network. In conclusion, the findings contribute new supportive direct imaging insight into the source of the enhanced H 2 evolution that accompanies anodic dissolution of Mg and its alloys.

  15. Laser collisional induced fluorescence electron density measurements as a function of ring bias and the onset of anode spot formation in a ring cusp magnetic field

    NASA Astrophysics Data System (ADS)

    Arthur, N. A.; Foster, J. E.; Barnat, E. V.

    2018-05-01

    Two-dimensional electron density measurements are made in a magnetic ring cusp discharge using laser collisional induced fluorescence. The magnet rings are isolated from the anode structure such that they can be biased independently in order to modulate electron flows through the magnetic cusps. Electron density images are captured as a function of bias voltage in order to assess the effects of current flow through the cusp on the spatial extent of the cusp. We anticipated that for a fixed current density being funneled through the magnetic cusp, the leak width would necessarily increase. Unexpectedly, the leak width, as measured by LCIF images, does not increase. This suggests that the current density is not constant, and that possibly either electrons are being heated or additional ionization events are occurring within the cusp. Spatially resolving electron temperature would be needed to determine if electrons are being heated within the cusp. We also observe breakdown of the anode magnetosheath and formation of anode spots at high bias voltage.

  16. Characteristic pattern of pleural effusion in electrical impedance tomography images of critically ill patients.

    PubMed

    Becher, T; Bußmeyer, M; Lautenschläger, I; Schädler, D; Weiler, N; Frerichs, I

    2018-06-01

    Electrical impedance tomography (EIT) is increasingly used for continuous monitoring of ventilation in intensive care patients. Clinical observations in patients with pleural effusion show an increase in out-of-phase impedance changes. We hypothesised that out-of-phase impedance changes are a typical EIT finding in patients with pleural effusion and could be useful in its detection. We conducted a prospective observational study in intensive care unit patients with and without pleural effusion. In patients with pleural effusion, EIT data were recorded before, during, and after unilateral drainage of pleural effusion. In patients with no pleural effusion, EIT data were recorded without any intervention. EIT images were separated into four quadrants of equal size. We analysed the sum of out-of-phase impedance changes in the affected quadrant in patients with pleural effusion before, during, and after drainage and compared it with the sum of out-of-phase impedance changes in the dorsal quadrants of patients without pleural effusion. We included 20 patients with pleural effusion and 10 patients without pleural effusion. The median sum of out-of-phase impedance changes was 70 (interquartile range 49-119) arbitrary units (a.u.) in patients with pleural effusion before drainage, 25 (12-46) a.u. after drainage (P<0.0001) and 11 (6-17) a.u. in patients without pleural effusion (P<0.0001 vs pleural effusion before drainage). The area under the receiver operating characteristics curve was 0.96 (95% limits of agreement 0.91-1.01) between patients with pleural effusion before drainage and those without pleural effusion. In patients monitored with EIT, the presence of out-of-phase impedance changes is highly suspicious of pleural effusion and should trigger further examination. Copyright © 2018 British Journal of Anaesthesia. Published by Elsevier Ltd. All rights reserved.

  17. Design of laser monitoring and sound localization system

    NASA Astrophysics Data System (ADS)

    Liu, Yu-long; Xu, Xi-ping; Dai, Yu-ming; Qiao, Yang

    2013-08-01

    In this paper, a novel design of laser monitoring and sound localization system is proposed. It utilizes laser to monitor and locate the position of the indoor conversation. In China most of the laser monitors no matter used in labor in an instrument uses photodiode or phototransistor as a detector at present. At the laser receivers of those facilities, light beams are adjusted to ensure that only part of the window in photodiodes or phototransistors received the beams. The reflection would deviate from its original path because of the vibration of the detected window, which would cause the changing of imaging spots in photodiode or phototransistor. However, such method is limited not only because it could bring in much stray light in receivers but also merely single output of photocurrent could be obtained. Therefore a new method based on quadrant detector is proposed. It utilizes the relation of the optical integral among quadrants to locate the position of imaging spots. This method could eliminate background disturbance and acquired two-dimensional spots vibrating data pacifically. The principle of this whole system could be described as follows. Collimated laser beams are reflected from vibrate-window caused by the vibration of sound source. Therefore reflected beams are modulated by vibration source. Such optical signals are collected by quadrant detectors and then are processed by photoelectric converters and corresponding circuits. Speech signals are eventually reconstructed. In addition, sound source localization is implemented by the means of detecting three different reflected light sources simultaneously. Indoor mathematical models based on the principle of Time Difference Of Arrival (TDOA) are established to calculate the twodimensional coordinate of sound source. Experiments showed that this system is able to monitor the indoor sound source beyond 15 meters with a high quality of speech reconstruction and to locate the sound source position accurately.

  18. Evaluation of the Anterior Segment Angle-to-Angle Scan of Cirrus High-Definition Optical Coherence Tomography and Comparison With Gonioscopy and With the Visante OCT.

    PubMed

    Tun, Tin A; Baskaran, Mani; Tan, Shayne S; Perera, Shamira A; Aung, Tin; Husain, Rahat

    2017-01-01

    To evaluate the diagnostic performance of the anterior segment angle-to-angle scan of the Cirrus high-definition optical coherence tomography (HD-OCT) in detecting eyes with closed angles. All subjects underwent dark-room gonioscopy by an ophthalmologist. A technician performed anterior segment imaging with Cirrus (n = 202) and Visante OCT (n = 85) under dark-room conditions. All eyes were categorized by two masked graders as per number of closed quadrants. Each quadrant of anterior chamber angle was categorized as a closed angle if posterior trabecular meshwork could not be seen on gonioscopy or if there was any irido-corneal contact anterior to scleral spur in Cirrus and Visante images. An eye was graded as having a closed angle if two or more quadrants were closed. Agreement and area under the curve (AUC) were performed. There were 50 (24.8%) eyes with closed angles. The agreements of closed-angle diagnosis (by eye) between Cirrus HD-OCT and gonioscopy (k = 0.59; 95% confidence interval (CI) 0.45-0.72; AC1 = 0.76) and between Cirrus and Visante OCT (k = 0.65; 95% CI 0.48-0.82, AC1 = 0.77) were moderate. The AUC for diagnosing the eye with gonioscopic closed angle by Cirrus HD-OCT was good (AUC = 0.86; sensitivity = 83.33; specificity = 77.78). The diagnostic performance of Cirrus HD-OCT in detecting the eyes with closed angles was similar to that of Visante (AUC 0.87 vs. 0.9, respectively; P = 0.51). The anterior segment angle-to-angle scans of Cirrus HD-OCT demonstrated similar diagnostic performance as Visante in detecting gonioscopic closed angles. The agreement between Cirrus and gonioscopy for detecting eyes with closed angles was moderate.

  19. Metal-based anode for high performance bioelectrochemical systems through photo-electrochemical interaction

    NASA Astrophysics Data System (ADS)

    Liang, Yuxiang; Feng, Huajun; Shen, Dongsheng; Long, Yuyang; Li, Na; Zhou, Yuyang; Ying, Xianbin; Gu, Yuan; Wang, Yanfeng

    2016-08-01

    This paper introduces a novel composite anode that uses light to enhance current generation and accelerate biofilm formation in bioelectrochemical systems. The composite anode is composed of 316L stainless steel substrate and a nanostructured α-Fe2O3 photocatalyst (PSS). The electrode properties, current generation, and biofilm properties of the anode are investigated. In terms of photocurrent, the optimal deposition and heat-treatment times are found to be 30 min and 2 min, respectively, which result in a maximum photocurrent of 0.6 A m-2. The start-up time of the PSS is 1.2 days and the maximum current density is 2.8 A m-2, twice and 25 times that of unmodified anode, respectively. The current density of the PSS remains stable during 20 days of illumination. Confocal laser scanning microscope images show that the PSS could benefit biofilm formation, while electrochemical impedance spectroscopy indicates that the PSS reduce the charge-transfer resistance of the anode. Our findings show that photo-electrochemical interaction is a promising way to enhance the biocompatibility of metal anodes for bioelectrochemical systems.

  20. Characterization and performance of anodic mixed culture biofilms in submersed microbial fuel cells.

    PubMed

    Saba, Beenish; Christy, Ann D; Yu, Zhongtang; Co, Anne C; Islam, Rafiq; Tuovinen, Olli H

    2017-02-01

    Microbial fuel cells (MFCs) were designed for laboratory scale experiments to study electroactive biofilms in anodic chambers. Anodic biofilms and current generation during biofilm growth were examined using single chambered MFCs submersed in algal catholyte. A culture of the marine green alga Nanochloropsis salina was used as a biocatholyte, and a rumen fluid microbiota was the anodic chamber inoculum. Electrical impedance spectroscopy was performed under varying external resistance once a week to identify mass transport limitations at the biofilm-electrolyte interface during the four-week experiment. The power generation increased from 249 to 461mWm -2 during the time course. Confocal laser scanning microscopy imaging showed that the depth of the bacterial biofilm on the anode was about 65μm. There were more viable bacteria on the biofilm surface and near the biofilm-electrolyte interface as compared to those close to the anode surface. The results suggest that biofilm growth on the anode creates a conductive layer, which can help overcome mass transport limitations in MFCs. Copyright © 2016 Elsevier B.V. All rights reserved.

  1. [Chronic appendicitis due to multiple fecaliths. A case report].

    PubMed

    Montiel-Jarquín, Álvaro José; Ramírez-Sánchez, Celso; García-Cano, Eugenio; González-Hernández, Nicolás; Rodríguez-Pérez, Fabiola; Alvarado-Ortega, Ivan

    2017-12-01

    The appendix inflammatory process is the most common cause of chronic abdominal pain in the right lower quadrant. The frequency of appendiceal lumen obstruction by fecalith ranges from 10 to 20%; few cases of obstruction by multiple fecaliths had been reported. Sixty-nine years old male, diabetic and hypertensive in control, he underwent bowel resection 30 years previously. He completed 6 months with intermittent, mild pain in the right lower quadrant abdomen; 14 days prior to admission with increasing pain, nausea, vomiting, constipation, abdominal distension and absence of peristalsis; 12,750 leukocytes, neutrophils 90%; plain abdominal radiography without specific bowel pattern, TAC with 3 dense images in right lower quadrant; exploratory laparotomy was performed and perforated appendix with 3 free fecaliths was found. Histopathological report showed fibrosis and lymphocytic infiltrate in the muscle layer of the cecal appendix consistent with chronic appendicitis. The most common obstruction of the appendix lumen is by a single fecalith. In this case the patient had chronic appendicitis secondary to appendiceal lumen obstruction by multiple fecaliths. Reviewing the international literature any case of chronic appendicitis associated with the presence of multiple fecaliths was found. Copyright © 2016 Academia Mexicana de Cirugía A.C. Publicado por Masson Doyma México S.A. All rights reserved.

  2. The Comparison of Regional RNFL and Fundus Vasculature by OCTA in Chinese Myopia Population.

    PubMed

    Li, Yuanjun; Miara, Hamza; Ouyang, Pingbo; Jiang, Bing

    2018-01-01

    To determine the correlations between peripapillary vessel density, retinal nerve fibre layer (RNFL) thickness, and myopic indices at retina quadrants with optical coherence tomography angiography (OCTA) in Chinese. Fifty-six subjects with a mean spherical equivalent (MSE) of -3.63 ± 0.29 D were included. Peripapillary RNFL thickness and retinal vessel density in four sectors (superior, nasal, inferior, and temporal quadrants) were determined by OCTA, and correlations of the main outcomes were analyzed. Negative correlations were found between the peripapillary RNFL thickness and axial length (AL) at superior ( r = -0.335, P = 0.001) and inferior ( r = -0.551, P < 0.001) quadrants. There was a significant positive correlation with spherical equivalent (SE) at the corresponding quadrants as well as at the nasal quadrant ( r = 0.339, P = 0.001; r = 0.379, P < 0.001; and r = 0.209, P = 0.039, resp.). Peripapillary retinal vessel density was also negatively correlated with AL at the nasal quadrant ( r = -0.392, P < 0.001), and only at the nasal quadrant, there was a positive correlation between the peripapillary vessel density and SE ( r = 0.319, P = 0.001). The degree of myopia and elongation of AL were negatively correlated with peripapillary RNFL thickness at superior and inferior quadrants and with peripapillary retinal vessel density at the nasal quadrant.

  3. The Comparison of Regional RNFL and Fundus Vasculature by OCTA in Chinese Myopia Population

    PubMed Central

    2018-01-01

    Purpose To determine the correlations between peripapillary vessel density, retinal nerve fibre layer (RNFL) thickness, and myopic indices at retina quadrants with optical coherence tomography angiography (OCTA) in Chinese. Methods Fifty-six subjects with a mean spherical equivalent (MSE) of −3.63 ± 0.29 D were included. Peripapillary RNFL thickness and retinal vessel density in four sectors (superior, nasal, inferior, and temporal quadrants) were determined by OCTA, and correlations of the main outcomes were analyzed. Results Negative correlations were found between the peripapillary RNFL thickness and axial length (AL) at superior (r = −0.335, P = 0.001) and inferior (r = −0.551, P < 0.001) quadrants. There was a significant positive correlation with spherical equivalent (SE) at the corresponding quadrants as well as at the nasal quadrant (r = 0.339, P = 0.001; r = 0.379, P < 0.001; and r = 0.209, P = 0.039, resp.). Peripapillary retinal vessel density was also negatively correlated with AL at the nasal quadrant (r = −0.392, P < 0.001), and only at the nasal quadrant, there was a positive correlation between the peripapillary vessel density and SE (r = 0.319, P = 0.001). Conclusions The degree of myopia and elongation of AL were negatively correlated with peripapillary RNFL thickness at superior and inferior quadrants and with peripapillary retinal vessel density at the nasal quadrant. PMID:29651341

  4. ION ACCELERATOR

    DOEpatents

    Bell, J.S.

    1959-09-15

    An arrangement for the drift tubes in a linear accelerator is described whereby each drift tube acts to shield the particles from the influence of the accelerating field and focuses the particles passing through the tube. In one embodiment the drift tube is splii longitudinally into quadrants supported along the axis of the accelerator by webs from a yoke, the quadrants. webs, and yoke being of magnetic material. A magnetic focusing action is produced by energizing a winding on each web to set up a magnetic field between adjacent quadrants. In the other embodiment the quadrants are electrically insulated from each other and have opposite polarity voltages on adjacent quadrants to provide an electric focusing fleld for the particles, with the quadrants spaced sufficienily close enough to shield the particles within the tube from the accelerating electric field.

  5. Single-photon counting multicolor multiphoton fluorescence microscope.

    PubMed

    Buehler, Christof; Kim, Ki H; Greuter, Urs; Schlumpf, Nick; So, Peter T C

    2005-01-01

    We present a multicolor multiphoton fluorescence microscope with single-photon counting sensitivity. The system integrates a standard multiphoton fluorescence microscope, an optical grating spectrograph operating in the UV-Vis wavelength region, and a 16-anode photomultiplier tube (PMT). The major technical innovation is in the development of a multichannel photon counting card (mC-PhCC) for direct signal collection from multi-anode PMTs. The electronic design of the mC-PhCC employs a high-throughput, fully-parallel, single-photon counting scheme along with a high-speed electrical or fiber-optical link interface to the data acquisition computer. There is no electronic crosstalk among the detection channels of the mC-PhCC. The collected signal remains linear up to an incident photon rate of 10(8) counts per second. The high-speed data interface offers ample bandwidth for real-time readout: 2 MByte lambda-stacks composed of 16 spectral channels, 256 x 256 pixel image with 12-bit dynamic range can be transferred at 30 frames per second. The modular design of the mC-PhCC can be readily extended to accommodate PMTs of more anodes. Data acquisition from a 64-anode PMT has been verified. As a demonstration of system performance, spectrally resolved images of fluorescent latex spheres and ex-vivo human skin are reported. The multicolor multiphoton microscope is suitable for highly sensitive, real-time, spectrally-resolved three-dimensional imaging in biomedical applications.

  6. Association Between Missing Posterior Teeth and Occurrence of Temporomandibular Joint Condylar Erosion: A Cone Beam Computed Tomography Study.

    PubMed

    Bertram, Felix; Hupp, Linus; Schnabl, Dagmar; Rudisch, Ansgar; Emshoff, Rüdiger

    To determine a possible association between asymptomatic temporomandibular joint (TMJ) condylar erosion and the number of missing posterior teeth and their location, as well as the number of dental quadrants with missing posterior teeth. This case-control study involved 210 patients (male to female ratio = 98:112) aged 16-74 years, with 105 asymptomatic patients with TMJ condylar erosion and a control group of 105 patients without TMJ condylar erosion. Cone beam computed tomography images were evaluated to classify the severity of TMJ condylar erosion as grade 0 (absence of erosion), grade I (slight erosion), grade II (moderate erosion), or grade III (extensive erosion). The number of missing posterior teeth (mean ± standard deviation [SD]; 2.7 ± 2.4 vs 0.7 ± 1.2) (P < .001), number of dental quadrants with missing posterior teeth (1.5 ± 1.3 vs 0.6 ± 0.9) (P < .001), and bilateral location of missing posterior teeth (41 ± 39.0 vs 10 ± 9.5) (P < .001) were all significantly higher in patients with erosion than in those without erosion. The condylar erosion grade was significantly associated with the number of missing posterior teeth (odds ratio [OR] = 1.24; P = .006), the number of dental quadrants with missing posterior teeth (OR = 1.36; P = .006), and the bilateral occurrence of missing posterior teeth (OR = 3.03; P = .002). The findings from this study suggest a possible association between TMJ condylar erosion grades and the number of missing posterior teeth, the number of quadrants with missing posterior teeth, and the bilateral occurrence of missing posterior teeth.

  7. Collagen Fiber Orientation and Dispersion in the Upper Cervix of Non-Pregnant and Pregnant Women

    PubMed Central

    Myers, Kristin M.; Vink, Joy Y.; Wapner, Ronald J.; Hendon, Christine P.

    2016-01-01

    The structural integrity of the cervix in pregnancy is necessary for carrying a pregnancy until term, and the organization of human cervical tissue collagen likely plays an important role in the tissue’s structural function. Collagen fibers in the cervical extracellular matrix exhibit preferential directionality, and this collagen network ultrastructure is hypothesized to reorient and remodel during cervical softening and dilation at time of parturition. Within the cervix, the upper half is substantially loaded during pregnancy and is where the premature funneling starts to happen. To characterize the cervical collagen ultrastructure for the upper half of the human cervix, we imaged whole axial tissue slices from non-pregnant and pregnant women undergoing hysterectomy or cesarean hysterectomy respectively using optical coherence tomography (OCT) and implemented a pixel-wise fiber orientation tracking method to measure the distribution of fiber orientation. The collagen fiber orientation maps show that there are two radial zones and the preferential fiber direction is circumferential in a dominant outer radial zone. The OCT data also reveal that there are two anatomic regions with distinct fiber orientation and dispersion properties. These regions are labeled: Region 1—the posterior and anterior quadrants in the outer radial zone and Region 2—the left and right quadrants in the outer radial zone and all quadrants in the inner radial zone. When comparing samples from nulliparous vs multiparous women, no differences in these fiber properties were noted. Pregnant tissue samples exhibit an overall higher fiber dispersion and more heterogeneous fiber properties within the sample than non-pregnant tissue. Collectively, these OCT data suggest that collagen fiber dispersion and directionality may play a role in cervical remodeling during pregnancy, where distinct remodeling properties exist according to anatomical quadrant. PMID:27898677

  8. Evaluation of retinal nerve fiber layer thickness and choroidal thickness in pseudoexfoliative glaucoma and pseudoexfoliative syndrome.

    PubMed

    Ozge, Gokhan; Koylu, Mehmet Talay; Mumcuoglu, Tarkan; Gundogan, Fatih Cakir; Ozgonul, Cem; Ayyildiz, Onder; Kucukevcilioglu, Murat

    2016-05-01

    To compare retinal nerve fiber layer thickness (RNFLT) and choroidal thickness (ChT) measurements in eyes with pseudoexfoliative (PEX) glaucoma, PEX syndrome and healthy control eyes. Eighteen patients with PEX glaucoma in one eye and PEX syndrome in the fellow eye were included. The right eyes of thirty-nine age- and sex-matched healthy subjects were included as control group. All participants underwent a detailed biomicroscopic and funduscopic examination. RNFLT and ChT measurements were performed with a commercially available spectral-domain optical coherence tomography (SD-OCT). ChT measurements were performed by using enhanced depth imaging (EDI) mode. Patients with PEX underwent diurnal IOP measurements with 4-hour intervals before inclusion in the study. RNFLT results included the average measurement and 6 quadrants (temporal, inferotemporal, inferonasal, nasal, superonasal and supero-temporal). ChT measurements were performed in the subfoveal region and around the fovea (500µm and 1500 µm nasal and temporal to the fovea), as well as around the optic disc (average peripapillary and eight quadrants in the peripapillary region (temporal, inferotemporal, inferior, inferonasal, nasal, superonasal, superior, supero-temporal)). RNFLT in all quadrants and average thickness were significantly lower in PEX glaucoma eyes compared to PEX syndrome eyes and healthy control eyes (p<0.001 for both). RNFLT comparisons between PEX syndrome and healthy control eyes did not show a significant difference (p>0.05) except the inferotemporal quadrant. ChT measurements were similar between groups (p>0.05). Thinning of the RNFL in association with unchanged ChT may mean that the presence of PEX material is a much more significant risk factor than choroidal changes in the progression of PEX syndrome to PEX glaucoma.

  9. Motion Tracking and Identification of Unrestraint Gait Rehabilitation by Use of Elderly Support Robot

    NASA Astrophysics Data System (ADS)

    Nokata, Makoto; Hirai, Wataru; Itatani, Ryosuke

    This paper presents a robotic training system that can exercise the user without bodily restraint, neither markers nor sensors are attached to the trainee. We developed the robot system that has a total of four mounted components: a laser sensor, a camera, a cushion, and an electric motor. This paper have showed the method used for determining whether the trainee was bending forward or backward while walking, and the extent of the tilt, using the recorded image of the back of the trainee's head. A characteristic of our software algorithms has been that the image was divided into 9 quadrants, and each quadrant undergoes Hough transformation. We have verified experimentally that by using our algorithms for the four patterns of forward, backward, diagonally, and crouching, the tilt of the trainee's body have been accurately determined. We created a flowchart for determining the direction of movement according to experimental results. By adjusting the values used to make the distinction according to the position and the angle of the camera, and the width of the back of the trainee's head, we were able to accurately determine the walking condition of the trainee, and achieve early detection of the start of a fall.

  10. A Detailed Look at the Performance Characteristics of the Lightning Imaging Sensor

    NASA Technical Reports Server (NTRS)

    Zhang, Daile; Cummins, Kenneth L.; Bitzer, Phillip; Koshak, William J.

    2018-01-01

    The Lightning Imaging Sensor (LIS) on board the Tropical Rainfall Measuring Mission (TRMM) effectively reached its end of life on April 15, 2015 after 17+ years of observation. Given the wealth of information in the archived LIS lightning data, and growing use of optical observations of lightning from space throughout the world, it is still of importance to better understand LIS calibration and performance characteristics. In this work, we continue our efforts to quantify the optical characteristics of the LIS pixel array, and to further characterize the detection efficiency and location accuracy of LIS. The LIS pixel array was partitioned into four quadrants, each having its own signal amplifier and digital conversion hardware. In addition, the sensor optics resulted in a decreasing sensitivity with increasing displacement from the center of the array. These engineering limitations resulted in differences in the optical emissions detected across the pixel array. Our work to date has shown a 20% increase in the count of the lightning events detected in one of the LIS quadrants, because of a lower detection threshold. In this study, we will discuss our work in progress on these limitations, and their potential impact on the group- and flash-level parameters.

  11. Two-Step Cycle for Producing Multiple Anodic Aluminum Oxide (AAO) Films with Increasing Long-Range Order

    PubMed Central

    2017-01-01

    Nanoporous anodic aluminum oxide (AAO) membranes are being used for an increasing number of applications. However, the original two-step anodization method in which the first anodization is sacrificial to pre-pattern the second is still widely used to produce them. This method provides relatively low throughput and material utilization as half of the films are discarded. An alternative scheme that relies on alternating anodization and cathodic delamination is demonstrated that allows for the fabrication of several AAO films with only one sacrificial layer thus greatly improving total aluminum to alumina yield. The thickness for which the cathodic delamination performs best to yield full, unbroken AAO sheets is around 85 μm. Additionally, an image analysis method is used to quantify the degree of long-range ordering of the unit cells in the AAO films which was found to increase with each successive iteration of the fabrication cycle. PMID:28630684

  12. Two-Step Cycle for Producing Multiple Anodic Aluminum Oxide (AAO) Films with Increasing Long-Range Order.

    PubMed

    Choudhary, Eric; Szalai, Veronika

    2016-01-01

    Nanoporous anodic aluminum oxide (AAO) membranes are being used for an increasing number of applications. However, the original two-step anodization method in which the first anodization is sacrificial to pre-pattern the second is still widely used to produce them. This method provides relatively low throughput and material utilization as half of the films are discarded. An alternative scheme that relies on alternating anodization and cathodic delamination is demonstrated that allows for the fabrication of several AAO films with only one sacrificial layer thus greatly improving total aluminum to alumina yield. The thickness for which the cathodic delamination performs best to yield full, unbroken AAO sheets is around 85 μm. Additionally, an image analysis method is used to quantify the degree of long-range ordering of the unit cells in the AAO films which was found to increase with each successive iteration of the fabrication cycle.

  13. Performance evaluation of a retrofit digital detector-based mammography system.

    PubMed

    Marshall, Nicholas W; van Ongeval, Chantal; Bosmans, Hilde

    2016-02-01

    A retrofit flat panel detector was integrated with a GE DMR+ analog mammography system and characterized using detective quantum efficiency (DQE). Technical system performance was evaluated using the European Guidelines protocol, followed by a limited evaluation of clinical image quality for 20 cases using image quality criteria in the European Guidelines. Optimal anode/filter selections were established using signal difference-to-noise ratio measurements. Only small differences in peak DQE were seen between the three anode/filter settings, with an average value of 0.53. For poly(methyl methacrylate) (PMMA) thicknesses above 60 mm, the Rh/Rh setting was the optimal anode/filter setting. The system required a mean glandular dose of 0.54 mGy at 30 kV Rh/Rh to reach the Acceptable gold thickness limit for 0.1 mm details. Imaging performance of the retrofit unit with the GE DMR+ is notably better than of powder based computed radiography systems and is comparable to current flat panel FFDM systems. Copyright © 2016 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

  14. Mathematical model of a DIC position sensing system within an optical trap

    NASA Astrophysics Data System (ADS)

    Wulff, Kurt D.; Cole, Daniel G.; Clark, Robert L.

    2005-08-01

    The quantitative study of displacements and forces of motor proteins and processes that occur at the microscopic level and below require a high level of sensitivity. For optical traps, two techniques for position sensing have been accepted and used quite extensively: quadrant photodiodes and an interferometric position sensing technique based on DIC imaging. While quadrant photodiodes have been studied in depth and mathematically characterized, a mathematical characterization of the interferometric position sensor has not been presented to the authors' knowledge. The interferometric position sensing method works off of the DIC imaging capabilities of a microscope. Circularly polarized light is sent into the microscope and the Wollaston prism used for DIC imaging splits the beam into its orthogonal components, displacing them by a set distance determined by the user. The distance between the axes of the beams is set so the beams overlap at the specimen plane and effectively share the trapped microsphere. A second prism then recombines the light beams and the exiting laser light's polarization is measured and related to position. In this paper we outline the mathematical characterization of a microsphere suspended in an optical trap using a DIC position sensing method. The sensitivity of this mathematical model is then compared to the QPD model. The mathematical model of a microsphere in an optical trap can serve as a calibration curve for an experimental setup.

  15. System for phase-contrast x-ray radiography using X pinch radiation and a method thereof

    DOEpatents

    Chandler, Katherine; Chelkovenko, Tatiana; Hammer, David; Pikuz, Sergei; Sinars, Daniel; Song, Byungmoo

    2007-11-06

    A radiograph system with an anode plate, a cathode plate, and a power source coupled to said anode plate and the cathode plate. At least two wires coupled between the anode plate and the cathode plate provide a configuration to form an X-pinch having a photon source size of less than five microns at energies above 2.5 keV. Material at the configuration forming the X-pinch vaporizes upon application of a suitable current to the wires forming a dense hot plasma and emitting a single x-ray pulse with sufficient photons having energies in the range of from about 2.5 keV to about 20 keV to provide a phase contrast image of an object in the path of the photons. Multiple simultaneous images may be formed of a plurality of objects. Suitable filters and x-ray detectors are provided.

  16. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sun, Yan; Xu, Ye; Yang, Ji

    Combining H I data from the Canadian Galactic Plane Survey and CO data from the Milky Way Imaging Scroll Painting project, we have identified a new segment of a spiral arm between Galactocentric radii of 15 and 19 kpc that apparently lies beyond the Outer Arm in the second Galactic quadrant. Over most of its length, the arm is 400-600 pc thick in z. The new arm appears to be the extension of the distant arm recently discovered by Dame and Thaddeus as well as the Scutum-Centaurus Arm into the outer second quadrant. Our current survey identified a total of 72more » molecular clouds with masses on the order of 10{sup 2}-10{sup 4} M {sub ☉} that probably lie in the new arm. When all of the available data from the CO molecular clouds are fit, the best-fitting spiral model gives a pitch angle of 9.°3 ± 0.°7.« less

  17. Multiwalled carbon nanotube@a-C@Co9S8 nanocomposites: a high-capacity and long-life anode material for advanced lithium ion batteries

    NASA Astrophysics Data System (ADS)

    Zhou, Yanli; Yan, Dong; Xu, Huayun; Liu, Shuo; Yang, Jian; Qian, Yitai

    2015-02-01

    A one-dimensional MWCNT@a-C@Co9S8 nanocomposite has been prepared via a facile solvothermal reaction followed by a calcination process. The amorphous carbon layer between Co9S8 and MWCNT acts as a linker to increase the loading of sulfides on MWCNT. When evaluated as anode materials for lithium ion batteries, the MWCNT@a-C@Co9S8 nanocomposite shows the advantages of high capacity and long life, superior to Co9S8 nanoparticles and MWCNT@Co9S8 nanocomposites. The reversible capacity could be retained at 662 mA h g-1 after 120 cycles at 1 A g-1. The efficient synthesis and excellent performances of this nanocomposite offer numerous opportunities for other sulfides as a new anode for lithium ion batteries.A one-dimensional MWCNT@a-C@Co9S8 nanocomposite has been prepared via a facile solvothermal reaction followed by a calcination process. The amorphous carbon layer between Co9S8 and MWCNT acts as a linker to increase the loading of sulfides on MWCNT. When evaluated as anode materials for lithium ion batteries, the MWCNT@a-C@Co9S8 nanocomposite shows the advantages of high capacity and long life, superior to Co9S8 nanoparticles and MWCNT@Co9S8 nanocomposites. The reversible capacity could be retained at 662 mA h g-1 after 120 cycles at 1 A g-1. The efficient synthesis and excellent performances of this nanocomposite offer numerous opportunities for other sulfides as a new anode for lithium ion batteries. Electronic supplementary information (ESI) available: Infrared spectrogram (IR) of glucose treated MWCNT; TEM images of MWCNT@a-C treated by different concentrations of glucose; SEM and TEM images of the intermediate product obtained from the solvothermal reaction between thiourea and Co(Ac)2; EDS spectrum of MWCNT@a-C@Co9S8 composites; SEM and TEM images of MWCNT@Co9S8 nanocomposites obtained without the hydrothermal treatment by glucose; SEM and TEM images of Co9S8 nanoparticles; Galvanostatic discharge-charge profiles and cycling performance of MWCNT@a-C; TEM images of the anode material at different state of charge (SOC) and depth of discharge (DOD); the comparison of cycling performances of reported cobalt sulfide nanocomposites. See DOI: 10.1039/c4nr07143c

  18. Optimal condition for fabricating superhydrophobic Aluminum surfaces with controlled anodizing processes

    NASA Astrophysics Data System (ADS)

    Saffari, Hamid; Sohrabi, Beheshteh; Noori, Mohammad Reza; Bahrami, Hamid Reza Talesh

    2018-03-01

    A single step anodizing process is used to produce micro-nano structures on Aluminum (1050) substrates with sulfuric acid as electrolyte. Therefore, surface energy of the anodized layer is reduced using stearic acid modification. Undoubtedly, effects of different parameters including anodizing time, electrical current, and type and concentration of electrolyte on the final contact angle are systemically studied and optimized. Results show that anodizing current of 0.41 A, electrolyte (sulfuric acid) concentration of 15 wt.% and anodizing time of 90 min are optimal conditions which give contact angle as high as 159.2° and sliding angle lower than 5°. Moreover, the study reveals that adding oxalic acid to the sulfuric acid cannot enhance superhydrophobicity of the samples. Also, scanning electron microscopy images of samples show that irregular (bird's nest) structures present on the surface instead of high-ordered honeycomb structures expecting from normal anodizing process. Additionally, X-ray diffraction analysis of the samples shows that only amorphous structures present on the surface. The Brunauer-Emmett-Teller (BET) specific surface area of the anodized layer is 2.55 m2 g-1 in optimal condition. Ultimately, the surface keeps its hydrophobicity in air and deionized water (DIW) after one week and 12 weeks, respectively.

  19. A simplified approach to predict performance degradation of a solid oxide fuel cell anode

    NASA Astrophysics Data System (ADS)

    Khan, Muhammad Zubair; Mehran, Muhammad Taqi; Song, Rak-Hyun; Lee, Jong-Won; Lee, Seung-Bok; Lim, Tak-Hyoung

    2018-07-01

    The agglomeration of nickel (Ni) particles in a Ni-cermet anode is a significant degradation phenomenon for solid oxide fuel cells (SOFCs). This work aims to predict the performance degradation of SOFCs due to Ni grain growth by using a simplified approach. Accelerated aging of Ni-scandia stabilized zirconia (SSZ) as an SOFC anode is carried out at 900 °C and subsequent microstructural evolution is investigated every 100 h up to 1000 h using scanning electron microscopy (SEM). The resulting morphological changes are quantified using a two-dimensional image analysis technique that yields the particle size, phase proportion, and triple phase boundary (TPB) point distribution. The electrochemical properties of an anode-supported SOFC are characterized using electrochemical impedance spectroscopy (EIS). The changes of particle size and TPB length in the anode as a function of time are in excellent agreement with the power-law coarsening model. This model is further combined with an electrochemical model to predict the changes in the anode polarization resistance. The predicted polarization resistances are in good agreement with the experimentally obtained values. This model for prediction of anode lifetime provides deep insight into the time-dependent Ni agglomeration behavior and its impact on the electrochemical performance degradation of the SOFC anode.

  20. Effects of Coke Calcination Level on Pore Structure in Carbon Anodes

    NASA Astrophysics Data System (ADS)

    Fang, Ning; Xue, Jilai; Lang, Guanghui; Bao, Chongai; Gao, Shoulei

    2016-02-01

    Effects of coke calcination levels on pore structure of carbon anodes have been investigated. Bench anodes were prepared by 3 types of cokes with 4 calcination temperatures (800°C, 900°C, 1000°C and 1100°C). The cokes and anodes were characterized using hydrostatic method, air permeability determination, mercury porosimetry, image analysis and confocal microscopy (CSLM). The cokes with different calcination levels are almost the same in LC values (19-20 Å) and real density (1.967-1.985 g/cm3), while the anode containing coke calcined at 900°C has the lowest open porosity and air permeability. Pore size distribution (represented by Anode H sample) can be roughly divided into two ranges: small and medium pores in diameter of 10-400 μm and large pores of 400-580 μm. For the anode containing coke calcined at 800°C, a number of long, narrow pores in the pore size range of 400-580 μm are presented among cokes particles. Formation of these elongated pores may be attributed to coke shrinkages during the anode baking process, which may develop cracking in the anode under cell operations. More small or medium rounded pores with pore size range of 10-400 μm emerge in the anodes with coke calcination temperatures of 900°C, 1000°C and 1100°C, which may be generated due to release of volatiles from the carbon anode during baking. For the anode containing coke calcined at 1100°C, it is found that many rounded pores often closely surround large coke particles, which have potential to form elongated, narrow pores.

  1. Establishing Law and Order After Conflict

    DTIC Science & Technology

    2005-01-01

    the y-axis indicates the rule of law. This leads to four quadrants . We code the lower-left quadrant as successful, since it includes decreasing...levels of violence and an improving rule of law. The lower-right quadrant is mixed because it includes increasing levels of violence but an improving rule...of law. Cases in the upper-right quadrant are un- successful, since they have increasing levels of violence and a deterio- rating rule of law

  2. Visual Assessment on Coastal Cruise Tourism: A Preliminary Planning Using Importance Performance Analysis

    NASA Astrophysics Data System (ADS)

    Trisutomo, S.

    2017-07-01

    Importance-Performance Analysis (IPA) has been widely applied in many cases. In this research, IPA was applied to measure perceive on coastal tourism objects and its possibility to be developed as coastal cruise tourism in Makassar. Three objects, i.e. Akkarena recreational site, Losari public space at waterfront, and Paotere traditional Phinisi ships port, were selected and assessed visually from water area by a group of purposive resource persons. The importance and performance of 10 attributes of each site were scored using Likert scale from 1 to 5. Data were processed by SPSS-21 than resulted Cartesian graph which the scores were divided in four quadrants: Quadrant I concentric here, Quadrant II keep up the good work, Quadrant III low priority, and Quadrant IV possible overkill. The attributes in each quadrant could be considered as the platform for preliminary planning of coastal cruise tour in Makassar

  3. Research on detecting spot selection and signal pretreatment of four-quadrant detector

    NASA Astrophysics Data System (ADS)

    Liu, Wenli; Han, Shaokun

    2018-01-01

    The four-quadrant detector is a photoelectric position sensor based on the photovoltaic effect. It is widely used in many fields such as target azimuth measurement, end-guided weapon and so on. The selection of the spot and the calculation of the center position are one of the main factors that affect the accuracy of the position measurement of the fourquadrant detector. In order to improve the positioning accuracy of the four-quadrant detector, the method of determining the best spot size is obtained from the theoretical research. The output signal of the four-quadrant detector is a weak narrow pulse signal, which needs to be magnified and widened at high magnitudes. The signal preprocessing method is simulated and experimentally studied. Detecting the spot and the signal processing is realized by the four-quadrant detector, which is important for the use of quadrant detectors for high-precision position measurements.

  4. The morphological study of porous silicon formed by electrochemical anodization method

    NASA Astrophysics Data System (ADS)

    Suryana, R.; Sandi, D. K.; Nakatsuka, O.

    2018-03-01

    Due to its good physical and chemical properties, porous silicon (PSi) is very attractive to study. In this research, PSi has been fabricated on n-type Si (100) by the electrochemical anodization method. The electrolyte solution used was a mixture of HF (40%), ethanol (99%) and aquadest with volume ratio of 1:1:2, respectively. It was anodized on Si(100) surface at different current densities of 10 mA/cm2 and 20 mA/cm2 with the anodization time at each current density for 10 min, 20 min, and 30 min. The Scanning Electron Microscope (SEM) images showed that the PSi surfaces have inhomogeneous sized pores in the range of 95.00 nm–1.46 μm. The PSi layers with current density and anodization time of 10 mA/cm2 (10 min), 10mA/cm2 (20 min), and 20mA/cm2 (10 min) have spherical shaped pores while the others have some uncommon (cross sectional) shaped pores on surfaces. It is considered that the cross sectional shaped maybe caused by unstable the current during the electrochemical anodization process.

  5. US of Right Upper Quadrant Pain in the Emergency Department: Diagnosing beyond Gallbladder and Biliary Disease.

    PubMed

    Joshi, Gayatri; Crawford, Kevin A; Hanna, Tarek N; Herr, Keith D; Dahiya, Nirvikar; Menias, Christine O

    2018-01-01

    Acute cholecystitis is the most common diagnosable cause for right upper quadrant abdominal (RUQ) pain in patients who present to the emergency department (ED). However, over one-third of patients initially thought to have acute cholecystitis actually have RUQ pain attributable to other causes. Ultrasonography (US) is the primary imaging modality of choice for initial imaging assessment and serves as a fast, cost-effective, and dynamic modality to provide a definitive diagnosis or a considerably narrowed list of differential possibilities. Multiple organ systems are included at standard RUQ US, and a variety of ultrasonographically diagnosable disease processes can be identified, including conditions of hepatic, pancreatic, adrenal, renal, gastrointestinal, vascular, and thoracic origin, all of which may result in RUQ pain. In certain cases, subsequent computed tomography, magnetic resonance (MR) imaging, MR cholangiopancreatography, or cholescintigraphy may be considered, depending on the clinical situation and US findings. Familiarity with the spectrum of disease processes outside of the gallbladder and biliary tree that may manifest with RUQ pain and recognition at US of these alternative conditions is pivotal for early diagnosis and appropriate management. Diagnosis at the time of initial US can reduce unnecessary imaging and its consequences, including excess cost, radiation exposure, nephrotoxic contrast medium use, and time to diagnosis, thereby translating into improved patient care and outcome. This article (a) reviews the causes of RUQ pain identifiable at US using an organ-system approach, (b) illustrates the US appearance of select conditions from each organ system with multimodality imaging correlates, and (c) discusses the relevant pathophysiology and treatment of these entities to aid in efficient direction of management. Online supplemental material is available for this article. © RSNA, 2018.

  6. (In) Sensitivity to spatial distortion in natural scenes

    PubMed Central

    Bex, Peter J.

    2010-01-01

    The perception of object structure in the natural environment is remarkably stable under large variation in image size and projection, especially given our insensitivity to spatial position outside the fovea. Sensitivity to periodic spatial distortions that were introduced into one quadrant of gray-scale natural images was measured in a 4AFC task. Observers were able to detect the presence of distortions in unfamiliar images even though they did not significantly affect the amplitude spectrum. Sensitivity depended on the spatial period of the distortion and on the image structure at the location of the distortion. The results suggest that the detection of distortion involves decisions made in the late stages of image perception and is based on an expectation of the typical structure of natural scenes. PMID:20462324

  7. The impact of steam and current density on carbon formation from biomass gasification tar on Ni/YSZ, and Ni/CGO solid oxide fuel cell anodes

    NASA Astrophysics Data System (ADS)

    Mermelstein, Joshua; Millan, Marcos; Brandon, Nigel

    The combination of solid oxide fuel cells (SOFCs) and biomass gasification has the potential to become an attractive technology for the production of clean renewable energy. However the impact of tars, formed during biomass gasification, on the performance and durability of SOFC anodes has not been well established experimentally. This paper reports an experimental study on the mitigation of carbon formation arising from the exposure of the commonly used Ni/YSZ (yttria stabilized zirconia) and Ni/CGO (gadolinium-doped ceria) SOFC anodes to biomass gasification tars. Carbon formation and cell degradation was reduced through means of steam reforming of the tar over the nickel anode, and partial oxidation of benzene model tar via the transport of oxygen ions to the anode while operating the fuel cell under load. Thermodynamic calculations suggest that a threshold current density of 365 mA cm -2 was required to suppress carbon formation in dry conditions, which was consistent with the results of experiments conducted in this study. The importance of both anode microstructure and composition towards carbon deposition was seen in the comparison of Ni/YSZ and Ni/CGO anodes exposed to the biomass gasification tar. Under steam concentrations greater than the thermodynamic threshold for carbon deposition, Ni/YSZ anodes still exhibited cell degradation, as shown by increased polarization resistances, and carbon formation was seen using SEM imaging. Ni/CGO anodes were found to be more resilient to carbon formation than Ni/YSZ anodes, and displayed increased performance after each subsequent exposure to tar, likely due to continued reforming of condensed tar on the anode.

  8. Florid cemento osseous dysplasia in association with dentigerous cyst.

    PubMed

    Sanjai, Karpagaselvi; Kumarswamy, Jayalakshmi; Kumar, Vinod K; Patil, Archana

    2010-07-01

    We present a case of florid cemento-osseous dysplasia occurring in a 20-year-old Indian woman. The subject presented with three lesions involving the maxillary right quadrant, maxillary left quadrant and mandibular left quadrant. The mandibular left quadrant also demonstrated a cyst.The diagnosis was made by correlating the clinical presentation with that of the radiological and histopathological findings. This is a rare entity because of an unusual combination of Asian race along with the association of dentigerous cyst.

  9. Prototyping Energy Storage Components for Hybrid Power Source

    DTIC Science & Technology

    2009-12-11

    from suitable nanoporous ceramic ( anodized aluminum oxide – AAO ) and polymer (polycarbonate - PC, polyethylene terephtalate - PET) membranes . Metal...of NUC technology: a) sketch of structure, b) SEM image of membrane . The alumina membranes can be easily and inexpensively fabricated via anodization ...of aluminum foil. The pores are formed by self-assembly via pitting and reprecipation of metal oxide . Motivation The work is motivated by the

  10. Neural Network Analysis of Different Segmentation Strategies of Nerve Fiber Layer Assessment for Glaucoma Diagnosis.

    PubMed

    Larrosa, Jose M; Polo, Vicente; Ferreras, Antonio; García-Martín, Elena; Calvo, Pilar; Pablo, Luis E

    2015-12-01

    To compare the diagnostic performance of different segmentations of the nerve fiber layer (NFL) thickness measurements using an artificial neural network and to define the optimal number of sectors with best diagnostic ability for glaucoma diagnosis. A total of 117 glaucoma patients and 123 normal subjects were included in the study. NFL thickness measurements were performed using the Spectralis-OCT (Heidelberg Engineering) to obtain the NFL thickness average; measurements from 2 semicircles, 4 quadrants, and 6, 8, 12, 16, 24, 32, and 64 sectors; and 768 uniformly divided locations around the peripapillary NFL. An artificial neural network evaluation was performed to compare the influence of sector analysis on the diagnostic performance of optical coherence tomography. Receiver operating characteristic curves were used to compare the diagnostic ability of the different segmentation analyses. The 6 sectors divided by the horizontal division of the nasal and temporal quadrants were better than the 6 sectors divided by the vertical line through the superior and inferior quadrants [areas under curve, 0.778; 95% confidence interval (CI), 0.720-0.829 and 0.814; 95% CI, 0.759-0.861, respectively]. In the case of quadrants, clock quadrants (area under curve 0.770; 95% CI, 0.712-0.822) were better than the ISNT (inferior-superior-nasal-temporal) quadrants (area under curve, 0.770; 95% CI, 0.712-0.822; P=0.003). The first segmentation strategy that improved the diagnostic value of 4 ISNT quadrants was the 12-sector analysis (area under curve, 0.845; 95% CI, 0.793-0.889; P=0.001). The 2 best candidate strategies for the OCT report were the 12-sector analysis and the 4 planimetric quadrant (alternatively, the 4 clock quadrants) analysis.

  11. NASA Sees a Wider-Eyed Typhoon Soudelor Near Taiwan

    NASA Image and Video Library

    2017-12-08

    The MODIS instrument aboard NASA's Aqua satellite flew over Typhoon Soudelor on Aug. 7, 2015, at 4:40 UTC (12:40 a.m. EDT) as it was approaching Taiwan. Credits: NASA Goddard's MODIS Rapid Response Team Clouds in Typhoon Soudelor's western quadrant were already spreading over Taiwan early on August 7 when NASA's Aqua satellite passed overhead. Soudelor is expected to make landfall and cross central Taiwan today and make a second landfall in eastern China. NASA satellite imagery revealed that Soudelor's eye "opened" five more miles since August 4. On Aug. 7 at 4:40 UTC (12:40 a.m. EDT) the Moderate Resolution Imaging Spectroradiometer or MODIS instrument aboard NASA's Aqua satellite captured a visible-light image of Typhoon Soudelor as its western quadrant began brushing eastern Taiwan. The MODIS image showed Soudelor's 17-nautical-mile-wide eye and thick bands of powerful thunderstorms surrounded the storm and spiraled into the center. Just three days before, the eye was 5 nautical miles smaller when the storm was more intense. On Aug. 4 at 4:10 UTC (12:10 a.m. EDT) Aqua's MODIS image showed the eye was 12-nautical-mile-wide eye. At 1500 UTC (11 a.m. EDT) on August 7, 2015, the Joint Typhoon Warning Center (JTWC) noted that Typhoon Soudelor's maximum sustained winds increased from 90 knots (103.6 mph/166.7 kph) to 105 knots (120.8 mph / 194.5 kph). It was centered near 23.1 North latitude and 123.2 East longitude, about 183 nautical miles (210.6 miles/338.9 km) southeast of Taipei, Taiwan. It was moving to the west-northwest at 10 knots (11.5 mph/18.5 kph). For warnings and watches for Taiwan, visit the Central Weather Bureau website: www.cwb.gov.tw/eng/. For warnings in China, visit the China Meteorological Administration website: www.cma.gov.cn/en. Soudelor's final landfall is expected in eastern China on Saturday, August 8. Clouds in Typhoon Soudelor's western quadrant were already spreading over Taiwan early on August 7 when NASA's Aqua satellite passed overhead. Soudelor is expected to make landfall and cross central Taiwan today and make a second landfall in eastern China. NASA satellite imagery revealed that Soudelor's eye "opened" five more miles since August 4. On Aug. 7 at 4:40 UTC (12:40 a.m. EDT) the Moderate Resolution Imaging Spectroradiometer or MODIS instrument aboard NASA's Aqua satellite captured a visible-light image of Typhoon Soudelor as its western quadrant began brushing eastern Taiwan. The MODIS image showed Soudelor's 17-nautical-mile-wide eye and thick bands of powerful thunderstorms surrounded the storm and spiraled into the center. Just three days before, the eye was 5 nautical miles smaller when the storm was more intense. On Aug. 4 at 4:10 UTC (12:10 a.m. EDT) Aqua's MODIS image showed the eye was 12-nautical-mile-wide eye. At 1500 UTC (11 a.m. EDT) on August 7, 2015, the Joint Typhoon Warning Center (JTWC) noted that Typhoon Soudelor's maximum sustained winds increased from 90 knots (103.6 mph/166.7 kph) to 105 knots (120.8 mph / 194.5 kph). It was centered near 23.1 North latitude and 123.2 East longitude, about 183 nautical miles (210.6 miles/338.9 km) southeast of Taipei, Taiwan. It was moving to the west-northwest at 10 knots (11.5 mph/18.5 kph). For warnings and watches for Taiwan, visit the Central Weather Bureau website: www.cwb.gov.tw/eng/. For warnings in China, visit the China Meteorological Administration website: www.cma.gov.cn/en. Soudelor's final landfall is expected in eastern China on Saturday, August 8.

  12. Vertically aligned carbon nanotube emitter on metal foil for medical X-ray imaging.

    PubMed

    Ryu, Je Hwang; Kim, Wan Sun; Lee, Seung Ho; Eom, Young Ju; Park, Hun Kuk; Park, Kyu Chang

    2013-10-01

    A simple method is proposed for growing vertically aligned carbon nanotubes on metal foil using the triode direct current plasma-enhanced chemical vapor deposition (PECVD). The carbon nanotube (CNT) electron emitter was fabricated using fewer process steps with an acid treated metal substrate. The CNT emitter was used for X-ray generation, and the X-ray image of mouse's joint was obtained with an anode current of 0.5 mA at an anode bias of 60 kV. The simple fabrication of a well-aligned CNT with a protection layer on metal foil, and its X-ray application, were studied.

  13. Investigation of platinum and palladium as potential anodic catalysts for direct borohydride and ammonia borane fuel cells

    NASA Astrophysics Data System (ADS)

    Olu, Pierre-Yves; Deschamps, Fabien; Caldarella, Giuseppe; Chatenet, Marian; Job, Nathalie

    2015-11-01

    Platinum and palladium are investigated as anodic catalysts for direct borohydride and direct ammonia borane fuel cells (DBFC and DABFC). Half-cell characterizations performed at 25 °C using NH3BH3 or NaBH4 alkaline electrolytes demonstrate the lowest open-circuit potential and highest electrocatalytic activity for the NH3BH3 alkaline electrolyte for Pd and Pt rotating disk electrodes, respectively. Voltammograms performed in fuel cell configuration at 25 °C confirm this trend: the highest open circuit voltage (1.05 V) and peak power density (181 mW·cm-2) are monitored for DABFC using Pd/C and Pt/C anodes, respectively. Increasing the temperature heightens the peak power density (that reaches 420 mW·cm-2 at 60 °C for DBFC using Pt/C anodes), but strongly generates gas from the fuel hydrolysis, hindering the overall fuel cells performances. The anode texture strongly influences the fuel cell performances, highlighting: (i) that an open anode texture is required to efficiently circulate the anolyte and (ii) the difficulty to compare potential anodic catalysts characterized using different fuel cell setups within the literature. Furthermore, TEM imaging of Pt/C and Pd/C catalysts prior/post DBFC and DABFC operation shows fast degradation of the carbon-supported nanoparticles.

  14. Fires in Kamchatka Peninsula, Russia

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Numerous thermal anomalies were detected on the Kamchatka Peninsula in northeastern Russia in late June and early July by the Moderate Resolution Imaging Spectroradiometer (MODIS). Some of the anomalies (red dots) were fires, but at least one was the result of ongoing volcanic activity at one of the Peninsula's numerous active volcanoes. The erupting volcano, called Sheveluch, can be seen most clearly in the image from July 8, 2002. It is located in the upper right quadrant of the image, and appears as a grayish circular patch amid the surrounding green vegetation. In its center is a red dot indicating that MODIS detected a thermal signature coming from the restless volcano. Credit: Jacques Descloitres, MODIS Land Rapid Response Team, NASA/GSFC

  15. Thermal Neutron Imaging Using A New Pad-Based Position Sensitive Neutron Detector

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dioszegi I.; Vanier P.E.; Salwen C.

    2016-10-29

    Thermal neutrons (with mean energy of 25 meV) have a scattering mean free path of about 20 m in air. Therefore it is feasible to find localized thermal neutron sources up to ~30 m standoff distance using thermal neutron imaging. Coded aperture thermal neutron imaging was developed in our laboratory in the nineties, using He-3 filled wire chambers. Recently a new generation of coded-aperture neutron imagers has been developed. In the new design the ionization chamber has anode and cathode planes, where the anode is composed of an array of individual pads. The charge is collected on each of themore » individual 5x5 mm2 anode pads, (48x48 in total, corresponding to 24x24 cm2 sensitive area) and read out by application specific integrated circuits (ASICs). The high sensitivity of the ASICs allows unity gain operation mode. The new design has several advantages for field deployable imaging applications, compared to the previous generation of wire-grid based neutron detectors. Among these are the rugged design, lighter weight and use of non-flammable stopping gas. For standoff localization of thermalized neutron sources a low resolution (11x11 pixel) coded aperture mask has been fabricated. Using the new larger area detector and the coarse resolution mask we performed several standoff experiments using moderated californium and plutonium sources at Idaho National Laboratory. In this paper we will report on the development and performance of the new pad-based neutron camera, and present long range coded-aperture images of various thermalized neutron sources.« less

  16. Preparation of a porous Sn@C nanocomposite as a high-performance anode material for lithium-ion batteries

    NASA Astrophysics Data System (ADS)

    Zhang, Yanjun; Jiang, Li; Wang, Chunru

    2015-07-01

    A porous Sn@C nanocomposite was prepared via a facile hydrothermal method combined with a simple post-calcination process, using stannous octoate as the Sn source and glucose as the C source. The as-prepared Sn@C nanocomposite exhibited excellent electrochemical behavior with a high reversible capacity, long cycle life and good rate capability when used as an anode material for lithium ion batteries.A porous Sn@C nanocomposite was prepared via a facile hydrothermal method combined with a simple post-calcination process, using stannous octoate as the Sn source and glucose as the C source. The as-prepared Sn@C nanocomposite exhibited excellent electrochemical behavior with a high reversible capacity, long cycle life and good rate capability when used as an anode material for lithium ion batteries. Electronic supplementary information (ESI) available: Detailed experimental procedure and additional characterization, including a Raman spectrum, TGA curve, N2 adsorption-desorption isotherm, TEM images and SEM images. See DOI: 10.1039/c5nr03093e

  17. Image contrast enhancement of Ni/YSZ anode during the slice-and-view process in FIB-SEM.

    PubMed

    Liu, Shu-Sheng; Takayama, Akiko; Matsumura, Syo; Koyama, Michihisa

    2016-03-01

    Focused ion beam-scanning electron microscopy (FIB-SEM) is a widely used and easily operational equipment for three-dimensional reconstruction with flexible analysis volume. It has been using successfully and increasingly in the field of solid oxide fuel cell. However, the phase contrast of the SEM images is indistinct in many cases, which will bring difficulties to the image processing. Herein, the phase contrast of a conventional Ni/yttria stabilized zirconia anode is tuned in an FIB-SEM with In-Lens secondary electron (SE) and backscattered electron detectors. Two accessories, tungsten probe and carbon nozzle, are inserted during the observation. The former has no influence on the contrast. When the carbon nozzle is inserted, best and distinct contrast can be obtained by In-Lens SE detector. This method is novel for contrast enhancement. Phase segmentation of the image can be automatically performed. The related mechanism for different images is discussed. © 2015 The Authors Journal of Microscopy © 2015 Royal Microscopical Society.

  18. Quantum interference in laser-induced nonsequential double ionization

    NASA Astrophysics Data System (ADS)

    Quan, Wei; Hao, XiaoLei; Wang, YanLan; Chen, YongJu; Yu, ShaoGang; Xu, SongPo; Xiao, ZhiLei; Sun, RenPing; Lai, XuanYang; Hu, ShiLin; Liu, MingQing; Shu, Zheng; Wang, XiaoDong; Li, WeiDong; Becker, Wilhelm; Liu, XiaoJun; Chen, Jing

    2017-09-01

    Quantum interference plays an important role in various intense-laser-driven atomic phenomena, e.g., above-threshold ionization and high-order-harmonic generation, and provides a useful tool in ultrafast imaging of atomic and molecular structure and dynamics. However, it has eluded observation in nonsequential double ionization (NSDI), which serves as an ideal prototype to study electron-electron correlation. Thus far, NSDI usually could be well understood from a semiclassical perspective, where all quantum aspects have been ignored after the first electron has tunneled. Here we perform coincidence measurements for NSDI of xenon subject to laser pulses at 2400 nm. It is found that the intensity dependence of the asymmetry parameter between the yields in the second and fourth quadrants and those in the first and third quadrants of the electron-momentum-correlation distributions exhibits a peculiar fast oscillatory structure, which is beyond the scope of the semiclassical picture. Our theoretical analysis indicates that this oscillation can be attributed to interference between the contributions of different excited states in the recollision-excitation-with-subsequent-ionization channel. Our work demonstrates the significant role of quantum interference in NSDI and may create an additional pathway towards manipulation and imaging of the ultrafast atomic and molecular dynamics in intense laser fields.

  19. Diapycnal Advection by Double Diffusion and Turbulence in the Ocean

    DTIC Science & Technology

    1999-09-01

    quadrant of the map. To evaluate the significance of the finger-regime results, we have implemented a simple statistical test. The dissipation ratio...accepted in nearly all of quadrants I, III and IV of the finger-favorable regime. However, the data in quadrant II (Rp ɚ,Ri> 1) strongly supports the...region of parameter space ( quadrant II, (Rp ɚ,Ri> 1)). 44 1.01 R R R P p p 1.1 1.5 2.5 5 10 30 1001.01 1.1 1.5 2.5 5 10 30

  20. Fabrication and characterisation of embedded metal nanostructures by ion implantation with nanoporous anodic alumina masks

    NASA Astrophysics Data System (ADS)

    Guan, Wei; Peng, Nianhua; Jeynes, Christopher; Ghatak, Jay; Peng, Yong; Ross, Ian M.; Bhatta, Umananda M.; Inkson, Beverley J.; Möbus, Günter

    2013-07-01

    Lateral ordered Co, Pt and Co/Pt nanostructures were fabricated in SiO2 and Si3N4 substrates by high fluence metal ion implantation through periodic nanochannel membrane masks based on anodic aluminium oxides (AAO). The quality of nanopatterning transfer defined by various AAO masks in different substrates was examined by transmission electron microscopy (TEM) in both imaging and spectroscopy modes.

  1. Hydration and dehydration cycles in polymer electrolyte fuel cells operated with wet anode and dry cathode feed: A neutron imaging and modeling study

    NASA Astrophysics Data System (ADS)

    García-Salaberri, P. A.; Sánchez, D. G.; Boillat, P.; Vera, M.; Friedrich, K. A.

    2017-08-01

    Proper water management plays an essential role in the performance and durability of Polymer Electrolyte Fuel Cells (PEFCs), but it is challenged by the variety of water transport phenomena that take place in these devices. Previous experimental work has shown the existence of fluctuations between low and high current density levels in PEFCs operated with wet hydrogen and dry air feed. The alternation between both performance states is accompanied by strong changes in the high frequency resistance, suggesting a cyclic hydration and dehydration of the membrane. This peculiar scenario is examined here considering liquid water distributions from neutron imaging and predictions from a 3D two-phase non-isothermal model. The results show that the hydration-dehydration cycles are triggered by the periodic condensation and shedding of liquid water at the anode inlet. The input of liquid water humidifies the anode channel and offsets the membrane dry-out induced by the dry air stream, thus leading to the high-performance state. When liquid water is flushed out of the anode channel, the dehydration process takes over, and the cell comes back to the low-performance state. The predicted amplitude of the current oscillations grows with decreasing hydrogen and increasing air flow rates, in agreement with previous experimental data.

  2. 3-D Spatial Resolution of 350 μm Pitch Pixelated CdZnTe Detectors for Imaging Applications.

    PubMed

    Yin, Yongzhi; Chen, Ximeng; Wu, Heyu; Komarov, Sergey; Garson, Alfred; Li, Qiang; Guo, Qingzhen; Krawczynski, Henric; Meng, Ling-Jian; Tai, Yuan-Chuan

    2013-02-01

    We are currently investigating the feasibility of using highly pixelated Cadmium Zinc Telluride (CdZnTe) detectors for sub-500 μ m resolution PET imaging applications. A 20 mm × 20 mm × 5 mm CdZnTe substrate was fabricated with 350 μ m pitch pixels (250 μ m anode pixels with 100 μ m gap) and coplanar cathode. Charge sharing among the pixels of a 350 μ m pitch detector was studied using collimated 122 keV and 511 keV gamma ray sources. For a 350 μ m pitch CdZnTe detector, scatter plots of the charge signal of two neighboring pixels clearly show more charge sharing when the collimated beam hits the gap between adjacent pixels. Using collimated Co-57 and Ge-68 sources, we measured the count profiles and estimated the intrinsic spatial resolution of 350 μ m pitch detector biased at -1000 V. Depth of interaction was analyzed based on two methods, i.e., cathode/anode ratio and electron drift time, in both 122 keV and 511 keV measurements. For single-pixel photopeak events, a linear correlation between cathode/anode ratio and electron drift time was shown, which would be useful for estimating the DOI information and preserving image resolution in CdZnTe PET imaging applications.

  3. 3-D Spatial Resolution of 350 μm Pitch Pixelated CdZnTe Detectors for Imaging Applications

    PubMed Central

    Yin, Yongzhi; Chen, Ximeng; Wu, Heyu; Komarov, Sergey; Garson, Alfred; Li, Qiang; Guo, Qingzhen; Krawczynski, Henric; Meng, Ling-Jian; Tai, Yuan-Chuan

    2016-01-01

    We are currently investigating the feasibility of using highly pixelated Cadmium Zinc Telluride (CdZnTe) detectors for sub-500 μm resolution PET imaging applications. A 20 mm × 20 mm × 5 mm CdZnTe substrate was fabricated with 350 μm pitch pixels (250 μm anode pixels with 100 μm gap) and coplanar cathode. Charge sharing among the pixels of a 350 μm pitch detector was studied using collimated 122 keV and 511 keV gamma ray sources. For a 350 μm pitch CdZnTe detector, scatter plots of the charge signal of two neighboring pixels clearly show more charge sharing when the collimated beam hits the gap between adjacent pixels. Using collimated Co-57 and Ge-68 sources, we measured the count profiles and estimated the intrinsic spatial resolution of 350 μm pitch detector biased at −1000 V. Depth of interaction was analyzed based on two methods, i.e., cathode/anode ratio and electron drift time, in both 122 keV and 511 keV measurements. For single-pixel photopeak events, a linear correlation between cathode/anode ratio and electron drift time was shown, which would be useful for estimating the DOI information and preserving image resolution in CdZnTe PET imaging applications. PMID:28250476

  4. Mean glandular dose coefficients (D(g)N) for x-ray spectra used in contemporary breast imaging systems.

    PubMed

    Nosratieh, Anita; Hernandez, Andrew; Shen, Sam Z; Yaffe, Martin J; Seibert, J Anthony; Boone, John M

    2015-09-21

    To develop tables of normalized glandular dose coefficients D(g)N for a range of anode-filter combinations and tube voltages used in contemporary breast imaging systems. Previously published mono-energetic D(g)N values were used with various spectra to mathematically compute D(g)N coefficients. The tungsten anode spectra from TASMICS were used; molybdenum and rhodium anode-spectra were generated using MCNPX Monte Carlo code. The spectra were filtered with various thicknesses of Al, Rh, Mo or Cu. An initial half value layer (HVL) calculation was made using the anode and filter material. A range of the HVL values was produced with the addition of small thicknesses of polymethyl methacrylate (PMMA) as a surrogate for the breast compression paddle, to produce a range of HVL values at each tube voltage. Using a spectral weighting method, D(g)N coefficients for the generated spectra were calculated for breast glandular densities of 0%, 12.5%, 25%, 37.5%, 50% and 100% for a range of compressed breast thicknesses from 3 to 8 cm. Eleven tables of normalized glandular dose (D(g)N) coefficients were produced for the following anode/filter combinations: W + 50 μm Ag, W + 500 μm Al, W + 700 μm Al, W + 200 μm Cu, W + 300 μm Cu, W + 50 μm Rh, Mo + 400 μm Cu, Mo + 30 μm Mo, Mo + 25 μm Rh, Rh + 400 μm Cu and Rh + 25 μm Rh. Where possible, these results were compared to previously published D(g)N values and were found to be on average less than 2% different than previously reported values.Over 200 pages of D(g)N coefficients were computed for modeled x-ray system spectra that are used in a number of new breast imaging applications. The reported values were found to be in excellent agreement when compared to published values.

  5. Determinants of peripapillary retinal nerve fiber layer thickness regarding ocular and systemic parameters - the MIPH Eye&Health Study.

    PubMed

    Schuster, Alexander Karl-Georg; Fischer, Joachim Ernst; Vossmerbaeumer, Christine; Vossmerbaeumer, Urs

    2016-10-01

    Optical coherence tomography (OCT) allows quantitative image analysis of retinal tissue in vivo. Peripapillary retinal nerve fiber layer (pRNFL) thickness is widely used for evaluation of retinal nerve fiber rarefaction in several optic neuropathies. This study evaluates associations of pRNFL thickness in healthy adult subjects in order to evaluate influencing factors. A cross-sectional study was performed in a working-age population. Only eyes without detectable ocular pathologies were included in the analysis. Among analyzed systemic cardiovascular parameters were age, gender, body-mass index, mean arterial blood pressure, HbA1c, high- and low-density-lipoproteins, and triglycerides. A comprehensive ophthalmological examination including refraction, tonometry, keratometry, and central corneal thickness measurmentwas performed. In addition, pRNFL thickness was imaged by spectral-domain OCT. Univariable and multivariable associations of pRNFL thickness in all four quadrants and on average with systemic and ocular parameters were calculated using a generalized estimating equation model. Three hundred and six subjects were included. pRNFL thickness measurements showed a significant association with spherical equivalent: pRNFL thickness decreased with increasing myopia in all quadrants (multivariable regression coefficients Beta: superior: 1.16, 95 % CI [0.62;1.71], p < 0.001; temporal: 0.87, [0.33;1.41], p = 0.001; inferior: 1.80, [1.18;2.42], p < 0.001; nasal: 2.60, [2.01;3.20], p < 0.001) and on average (1.51, [1.20;1.82], p < 0.001). A thicker central cornea thickness was related to lower pRNFL in the superior (-0.05, [-0.10; -0.01], p = 0.01), the inferior quadrant (-0.05, [-0.10;0.00], p = 0.03) and on average (-0.04, [-0.07; -0.01], p = 0.02). All other parameters were not  associated. Our findings highlight the importance of refraction when evaluating pRNFL thickness and its independence from other systemic parameters.

  6. Gonad dose in AP pelvis radiography: Impact of anode heel orientation.

    PubMed

    Mraity, H A A B; England, A; Hogg, P

    2017-02-01

    For antero posterior (AP) pelvis radiographic examination, determine the impact of anode heel orientation on female/male gonad dose. High sensitivity thermo-luminescent dosimeters (TLDs) were used with an ATOM dosimetry phantom; the phantom was positioned for AP pelvis. TLDs were placed into the testes and ovaries. Radiation dose received by these organs was measured with the feet toward anode and feet toward the cathode. kVp, mAs and SID were manipulated to generate a range of exposures. A dose profile was also generated using Unfors Mult-O-Meter 401 along the long axis of the phantom. A decrease in dose from the central ray toward the anode was noted, with a marked increase toward the cathode. A significant reduction in dose was received by the testes with feet towards the anode compared with feet towards cathode (P˂0.001). No difference was seen for ovarian dose (P˃0.05). kVp, mAs and SID all have an effect on male and female gonad dose. For male pelvis imaging, placing feet towards the anode can be used as a simple dose reduction method. Copyright © 2016 The College of Radiographers. Published by Elsevier Ltd. All rights reserved.

  7. Effects of Anode Flow Field Design on CO2 Bubble Behavior in μDMFC

    PubMed Central

    Li, Miaomiao; Liang, Junsheng; Liu, Chong; Sun, Gongquan; Zhao, Gang

    2009-01-01

    Clogging of anode flow channels by CO2 bubbles is a vital problem for further performance improvements of the micro direct methanol fuel cell (μDMFC). In this paper, a new type anode structure using the concept of the non-equipotent serpentine flow field (NESFF) to solve this problem was designed, fabricated and tested. Experiments comparing the μDMFC with and without this type of anode flow field were implemented using a home-made test loop. Results show that the mean-value, amplitude and frequency of the inlet-to-outlet pressure drops in the NESFF is far lower than that in the traditional flow fields at high μDMFC output current. Furthermore, the sequential images of the CO2 bubbles as well as the μDMFC performance with different anode flow field pattern were also investigated, and the conclusions are in accordance with those derived from the pressure drop experiments. Results of this study indicate that the non-equipotent design of the μDMFC anode flow field can effectively mitigate the CO2 clogging in the flow channels, and hence lead to a significant promotion of the μDMFC performance. PMID:22412313

  8. Natural history of Leber's hereditary optic neuropathy: longitudinal analysis of the retinal nerve fiber layer by optical coherence tomography.

    PubMed

    Barboni, Piero; Carbonelli, Michele; Savini, Giacomo; Ramos, Carolina do V F; Carta, Arturo; Berezovsky, Adriana; Salomao, Solange R; Carelli, Valerio; Sadun, Alfredo A

    2010-03-01

    To investigate by optical coherence tomography (OCT) the topographic pattern and temporal sequence of fiber loss in the peripapillary retinal nerve fiber layer (RNFL) of patients with Leber's hereditary optic neuropathy (LHON) in a longitudinal follow-up. Cohort study. Six eyes of 4 patients with molecularly defined LHON were enrolled before the subacute period of visual loss. Subjects were studied by StratusOCT (Carl Zeiss Meditec, Inc., Dublin, CA) during a 9-month follow-up starting from the presymptomatic stage of the disease. Examinations were carried out at 4 different time points: presymptomatic stage, time of visual loss, and 3 and 9 months later. Peripapillary RNFL thickness for each quadrant of the optic nerve. Statistical comparisons were performed by ordinary analysis of variance with Dunnett's post-test. A significant increase of RNFL thickness was detected in the temporal and inferior quadrants between the presymptomatic stage and the disease onset (P<0.05). The 360-degree average and the superior and nasal quadrants showed a nonstatistically significant increase of thickness at this time. In the 360-degree average (P<0.01), superior (P<0.01), nasal (P<0.05), and inferior (P<0.01) quadrants, RNFL thickening showed statistically significant changes between the presymptomatic stage and the 3-month follow-up. At 3 months, a nonsignificant reduction of RNFL thickness was detected in the temporal quadrant. A significant reduction of RNFL was detected in all but the nasal quadrants between the presymptomatic stage and the 9-month Follow-up. The RNFL thickness increase first appeared at the temporal and inferior quadrants. Conversely, at 3 months the thickening fibers were more evident in the superior and nasal quadrants. These findings are consistent with the established preferential early involvement of the papillomacular bundle in LHON. We also demonstrated the previously unrecognized simultaneous early involvement of the inferior quadrant. The late involvement of both superior and nasal quadrants suggests a dynamic evolution of the acute stage that continues for 3 months and may represent a therapeutic window of opportunity. Copyright 2010 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

  9. Specific Location of Disc Hemorrhage is Linked to Nerve Fiber Layer Defects.

    PubMed

    Yoo, Young Cheol; Kim, Joon Mo; Park, Han Seok; Yoo, Chungkwon; Shim, Seong Hee; Won, Yu Sam; Park, Ki Ho; Chang, Robert T

    2017-06-01

    To investigate the relationship between retinal nerve fiber layer (RNFL) defects and the quadrant and proximal location of disc hemorrhages (DHs) in a large population examined for health screening. A total of 168,044 subjects older than 20 years underwent a single screening ophthalmic examination with color fundus photography as part of a comprehensive health screening program. The presence and location of DHs and RNFL defects were assessed. The DH locations were defined according to the quadrant location (inferotemporal, superotemporal, inferonasal, or superonasal) and the most proximal end of DHs relative to the disc center (cup base, cup margin, disc rim, or extrapapillary region). Using these two location descriptors as independent variables, a logistic regression analysis was conducted to explore the effects of DH location on RNFL defects. Two hundred twenty-six eyes had DH and 120 (53.1%) of them had RNFL defects. After adjusting for proximal location, DHs located in the inferotemporal quadrant accompanied RFNL defects 12 times more frequently than those in the superonasal quadrant (odds ratio [OR], 11.81; P = .004). Conversely, after adjusting for quadrant location, the ORs for an associated RNFL defect were 3.73 (P < .001), 16.54 (P < .001), and 8.91 (P = .002) for DHs with the proximal end at the disc rim, cup margin, and cup base, respectively. Among the four quadrants and four proximal locations, DHs were identified most frequently in the inferotemporal quadrant and outside the disc, respectively. Some DH locations, such as the inferotemporal quadrant and the cup margin, were associated with RNFL defects, whereas others were not.

  10. An Integral Approach to Counseling Ethics

    ERIC Educational Resources Information Center

    Foster, Durwin; Black, Timothy G.

    2007-01-01

    The authors offer an integral approach to counseling ethics using K. Wilber's (2000a, 2000b) integral metatheory. The article examines traditional counseling ethics through the lens of K. Wilber's (2000a, 2000b) "all-quadrants, all-levels" model, consisting of quadrants, levels, lines, states, and types. The authors begin with the 4 quadrants and…

  11. Quadrant Analysis as a Strategic Planning Technique in Curriculum Development and Program Marketing.

    ERIC Educational Resources Information Center

    Lynch, James; And Others

    1996-01-01

    Quadrant analysis, a widely-used research technique, is suggested as useful in college or university strategic planning. The technique uses consumer preference data and produces information suitable for a wide variety of curriculum and marketing decisions. Basic quadrant analysis design is described, and advanced variations are discussed, with…

  12. Four-quadrant gratings moiré fringe alignment measurement in proximity lithography.

    PubMed

    Zhu, Jiangping; Hu, Song; Yu, Junsheng; Zhou, Shaolin; Tang, Yan; Zhong, Min; Zhao, Lixin; Chen, Minyong; Li, Lanlan; He, Yu; Jiang, Wei

    2013-02-11

    This paper aims to deal with a four-quadrant gratings alignment method benefiting from phase demodulation for proximity lithography, which combines the advantages of interferometry with image processing. Both the mask alignment mark and the wafer alignment mark consist of four sets of gratings, which bring the convenience and simplification of realization for coarse alignment and fine alignment. Four sets of moiré fringes created by superposing the mask alignment mark and the wafer alignment mark are highly sensitive to the misalignment between them. And the misalignment can be easily determined through demodulating the phase of moiré fringe without any external reference. Especially, the period and phase distribution of moiré fringes are unaffected by the gap between the mask and the wafer, not excepting the wavelength of alignment illumination. Disturbance from the illumination can also be negligible, which enhances the technological adaptability. The experimental results bear out the feasibility and rationality of our designed approach.

  13. Color in graphic design: an analysis of meaning and trends

    NASA Astrophysics Data System (ADS)

    Martinson, Barbara; Waldron, Carol C.

    2002-06-01

    Graphic design is visual communication through the selection, arrangement, and presentation of words and images, most often for the printed page which offer the designer almost limitless options for color use. The objective of this project is to identify patterns of color use. Ethnographic content analysis was used to document color use in annual reports represented in two publications, Print and Communication Arts, 1993-2000. The analysis focuses on the selection, combination, and contrast of hues; and their use with achromatic values. An analysis of the entire sample indicates that one-third of the annual reports used a palette that include black, white, and a hue from quadrant one (red to yellow). Nearly one-fifth of the designs used black, white, and colors from quadrants one and three (cyan to blue). The large samples for Technology, Health Sciences, Financial, and Civic organizations follow the first pattern. Food Service, Business products and services, and Transportation industries favor the second pattern.

  14. Medical Approach to Right Colon Diverticulitis with Perforation.

    PubMed

    Espinosa, James; Sharma, Rahul; Lucerna, Alan; Stranges, Doug

    2017-01-01

    We report a case of a 71-year-old female who presented with right lower quadrant (RLQ) abdominal pain and was diagnosed on CT scan with right-sided diverticulitis with perforation. She was admitted under the surgical service after consultation and received intravenous fluids, intravenous antibiotics, and pain medications as needed. The patient was discharged 2 days after admission in stable condition with follow-up with gastroenterology. The differential diagnosis of right lower quadrant abdominal pain is vast. Right-sided diverticulitis often presents in a manner similar to appendicitis. In the absence of peritonitis, conservative treatment may be possible. It is predictable that as the population ages, the incidence of right-sided diverticular disease will increase and will result in more presentations of acute right-sided diverticulitis to the emergency department (ED). The aim of this case report is to increase awareness of the incidence, pathophysiology, presentation, work-up (laboratory studies and imaging), and management (medical and surgical) of right-sided diverticulitis among emergency physicians.

  15. Solid oxide fuel cell anode image segmentation based on a novel quantum-inspired fuzzy clustering

    NASA Astrophysics Data System (ADS)

    Fu, Xiaowei; Xiang, Yuhan; Chen, Li; Xu, Xin; Li, Xi

    2015-12-01

    High quality microstructure modeling can optimize the design of fuel cells. For three-phase accurate identification of Solid Oxide Fuel Cell (SOFC) microstructure, this paper proposes a novel image segmentation method on YSZ/Ni anode Optical Microscopic (OM) images. According to Quantum Signal Processing (QSP), the proposed approach exploits a quantum-inspired adaptive fuzziness factor to adaptively estimate the energy function in the fuzzy system based on Markov Random Filed (MRF). Before defuzzification, a quantum-inspired probability distribution based on distance and gray correction is proposed, which can adaptively adjust the inaccurate probability estimation of uncertain points caused by noises and edge points. In this study, the proposed method improves accuracy and effectiveness of three-phase identification on the micro-investigation. It provides firm foundation to investigate the microstructural evolution and its related properties.

  16. A High-Resolution Time-of-Flight Clinical PET Detection System Using a Gapless PMT-Quadrant-Sharing Method

    NASA Astrophysics Data System (ADS)

    Wong, Wai-Hoi; Li, Hongdi; Zhang, Yuxuan; Ramirez, Rocio; An, Shaohui; Wang, Chao; Liu, Shitao; Dong, Yun; Baghaei, Hossain

    2015-10-01

    We developed a high-resolution Photomultiplier-Quadrant-Sharing (PQS) PET system for human imaging. This system is made up of 24 detector panels. Each panel (bank) consists of 3 ×7 detector blocks, and each block has 16 ×16 LYSO crystals of 2.35 ×2.35 ×15.2 mm3. We used a novel detector-grinding scheme that is compatible with the PQS detector-pixel-decoding requirements to make a gapless cylindrical detector ring for maximizing detection efficiency while delivering an ultrahigh spatial-resolution for a whole-body PET camera with a ring diameter of 87 cm and axial field of view of 27.6 cm. This grinding scheme enables two adjacent gapless panels to share one row of the PMTs to extend the PQS configuration beyond one panel and thus maximize the economic benefit (in PMT usage) of the PQS design. The entire detector ring has 129,024 crystals, all of which are clearly decoded using only 576 PMTs (38-mm diameter). Thus, each PMT on average decodes 224 crystals to achieve a high crystal-pitch resolution of 2.44 mm ×2.44 mm. The detector blocks were mass-produced with our slab-sandwich-slice technique using a set of optimized mirror-film patterns (between crystals) to maximize light output and achieve high spatial and timing resolution. This detection system with time-of-flight capability was placed in a human PET/CT gantry. The reconstructed image resolution of the system was about 2.87 mm using 2D-filtered back-projection. The time-of-flight resolution was 473 ps. The preliminary images of phantoms and clinical studies presented in this work demonstrate the capability of this new PET/CT system to produce high-quality images.

  17. Fluorescent Microscopy Enhancement Using Imaging

    NASA Astrophysics Data System (ADS)

    Conrad, Morgan P.; Reck tenwald, Diether J.; Woodhouse, Bryan S.

    1986-06-01

    To enhance our capabilities for observing fluorescent stains in biological systems, we are developing a low cost imaging system based around an IBM AT microcomputer and a commercial image capture board compatible with a standard RS-170 format video camera. The image is digitized in real time with 256 grey levels, while being displayed and also stored in memory. The software allows for interactive processing of the data, such as histogram equalization or pseudocolor enhancement of the display. The entire image, or a quadrant thereof, can be averaged over time to improve the signal to noise ratio. Images may be stored to disk for later use or comparison. The camera may be selected for better response in the UV or near IR. Combined with signal averaging, this increases the sensitivity relative to that of the human eye, while still allowing for the fluorescence distribution on either the surface or internal cytoskeletal structure to be observed.

  18. Ring Imaging Cerenkov Detector for CLAS12

    NASA Astrophysics Data System (ADS)

    Muhoza, Mireille; Aaron, Elise; Smoot, Waymond; Benmokhtar, Fatiha

    2017-09-01

    The CLAS12 detector at Thomas Jefferson National Accelerator Facility (TJNAF) is undergoing an upgrade. One of the additions to this detector is a Ring Imaging Cherenkov (RICH) detector to improve particle identification in the 3-8 GeV/c momentum range. Approximately 400 multi anode photomultiplier tubes (MAPMTs) will be used to detect Cherenkov Radiation in the single photoelectron spectra (SPS). Detector tests are taking place at Jefferson Lab, while analysis software development is ongoing at Duquesne. I will be summarizing the work done at Duquesne on the Database development and the analysis of the ADC and TDCs for the Hamamatsu Multi-Anode PMTs that are used for Cerenkov light radiation. National Science Foundation, Award 1615067.

  19. The Effect of Silane on the Microstructure, Corrosion, and Abrasion Resistances of the Anodic Films on Ti Alloy

    NASA Astrophysics Data System (ADS)

    Wang, Jinwei; Chen, Jiali

    2016-04-01

    Anodic oxide films on Ti-6Al-4V alloy are prepared using sodium hydroxide as the base electrolyte containing aminopropyl trimethoxysilane (APS) as an additive. Some APS undergo hydrolysis, adsorption, and chemical reaction with the TiO x to form Ti-O-Si bond as confirmed by ATR-FTIR and XPS spectra, and in turn their surface appearance and roughness are greatly changed with the addition of APS as observed by their SEM images. These amino anodic films possess much higher corrosive resistances since the formation of Ti-O-Si complex enhances the compactness of the anodic films and the existence of aminopropyl groups inside the pores provides additional blocking effects. Besides, their improvement in anti-abrasive capability is attributed to the toughening effect of the chemically bonded silanes and the lubrication functions from both the chemically bonded and physically absorbed silanes between the touched interfaces.

  20. Detrapping of tungsten nanoparticles in a direct-current argon glow discharge

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Couëdel, L., E-mail: lenaic.couedel@univ-amu.fr; Kumar, K. Kishor; Arnas, C.

    2014-12-15

    Nanoparticles are grown from the sputtering of a tungsten cathode in a direct current argon glow discharge. Laser light scattering of a vertical laser sheet going through the plasma reveals that the dust particle cloud is compressed and pushed towards the anode during the discharge. Scanning electron microscopy images of substrates exposed to the plasma for given durations show that dust particles are continuously falling down on the anode during the discharge. These observations are explained by the fact that the electrostatic force at the negative glow-anode sheath boundary cannot balance the ion drag, gravity, and thermophoresis forces for particlesmore » of more than a few tens of nanometres in diameter.« less

  1. Polypyrrole/sargassum activated carbon modified stainless-steel sponge as high-performance and low-cost bioanode for microbial fuel cells

    NASA Astrophysics Data System (ADS)

    Wu, Gaoming; Bao, Han; Xia, Zheng; Yang, Bin; Lei, Lecheng; Li, Zhongjian; Liu, Chunxian

    2018-04-01

    Anode materials, as the core component of microbial fuel cells (MFCs), have huge impacts on power generation performance and overall cost. Stainless-steel sponge (SS) can be a promising material for MFC anodes, due to its open continuous three-dimensional structure, high conductivity and low cost. However, poor biocompatibility limits its application. In this paper, a polypyrrole/sargassum activated carbon modified SS anode (Ppy/SAC/SS) is developed by electrochemical polymerization of pyrrole on the SS with the SAC as a dopant. The maximum power density achieved with the Ppy/SAC/SS anode is 45.2 W/m3, which is increased by 2 orders of magnitude and 2.9 times compared with an unmodified SS anode and a solely Ppy modified SS anode (Ppy/SS), respectively. In addition, the Ppy/SAC layer effectively eliminates electrochemical corrosion of the SS substrate. Electrochemical impedance spectroscopy reveals that Ppy/SAC modification decreases electron transfer resistance between the bacteria and the electrode. Furthermore, in vivo fluorescence imaging indicates that a more uniform biofilm is formed on the Ppy/SAC/SS compared to the unmodified SS and Ppy/SS. Due to the low cost of the materials, easy fabrication process and relatively high performance, our developed Ppy/SAC/SS can be a cost efficient anode material for MFCs in practical applications.

  2. Integrated packaging of 2D MOEMS mirrors with optical position feedback

    NASA Astrophysics Data System (ADS)

    Baumgart, M.; Lenzhofer, M.; Kremer, M. P.; Tortschanoff, A.

    2015-02-01

    Many applications of MOEMS microscanners rely on accurate position feedback. For MOEMS devices which do not have intrinsic on-chip feedback, position information can be provided with optical methods, most simply by using a reflection from the backside of a MOEMS scanner. By measuring the intensity distribution of the reflected beam across a quadrant diode, one can precisely detect the mirror's deflection angles. Previously, we have presented a position sensing device, applicable to arbitrary trajectories, which is based on the measurement of the position of the reflected laser beam with a quadrant diode. In this work, we present a novel setup, which comprises the optical position feedback functionality integrated into the device package itself. The new device's System-in-Package (SiP) design is based on a flip-folded 2.5D PCB layout and fully assembled as small as 9.2×7×4 mm³ in total. The device consists of four layers, which supply the MOEMS mirror, a spacer to provide the required optical path length, the quadrant photo-diode and a laser diode to serve as the light source. In addition to describing the mechanical setup of the novel device, we will present first experimental results and optical simulation studies. Accurate position feedback is the basis for closed-loop control of the MOEMS devices, which is crucial for some applications as image projection for example. Position feedback and the possibility of closed-loop control will significantly improve the performance of these devices.

  3. MARK’s Quadrant scoring system: a symptom-based targeted screening tool for gastric cancer

    PubMed Central

    Tata, Mahadevan D.; Gurunathan, Ramesh; Palayan, Kandasami

    2014-01-01

    Background Gastric cancer is notably one of the leading causes of cancer-related death in the world. In Malaysia, these patients present in the advanced stage, thus narrowing the treatment options and making the surgery nearly impossible for successful curative resection. Failure to identify high-risk patients and delay in diagnostic endoscope procedure contributed to the delay in diagnosis. The aim of the study was to develop and validate a scoring system (MARK’s Quadrant) which can identify symptomatic patients who are at risk for gastric cancer. Methods A 3-phase approach was undertaken: Phase 1: development of the weighted scoring system; Phase 2: estimating positive predicting value of MARK’s Quadrant; and Phase 3: a) testing the validity of MARK’s Quadrant in an open-access endoscope system; and b) comparing its usefulness compared to conventional referral system. Results In phases 1 and 2, MARK’s Quadrant with weighted symptoms was developed. The sensitivity of MARK’s Quadrant is 88% and the specificity is 45.5% to detect cancerous and precancerous lesions of gastric. This was confirmed by the prospective data from phase 3 of this study where the diagnostic yield of MARK’s Quadrant to detect any pathological lesion was 95.2%. This score has a high accuracy efficiency of 75%, hence comparing to routine referral system it has an odds ratio (95%CI) of 10.98 (4.63-26.00), 6.71 (4.46-10.09) and 0.95 (0.06-0.15) (P<0.001 respectively) for cancer, precancerous lesion and benign lesion diagnosis respectively. Conclusion MARK’s Quadrant is a useful tool to detect early gastric cancer among symptomatic patients in a low incidence region. PMID:24714557

  4. A self-supported metal-organic framework derived Co3O4 film prepared by an in-situ electrochemically assistant process as Li ion battery anodes

    NASA Astrophysics Data System (ADS)

    Zhao, Guangyu; Sun, Xin; Zhang, Li; Chen, Xuan; Mao, Yachun; Sun, Kening

    2018-06-01

    Derivates of metal-organic frameworks are promising materials of self-supported Li ion battery anodes due to the good dispersion of active materials, conductive scaffold, and mass transport channels in them. However, the discontinuous growth and poor adherence of metal-organic framework films on substrates hamper their development in self-supported electrodes. In the present study, cobalt-based metal-organic frameworks are anchored on Ti nanowire arrays through an electrochemically assistant method, and then the metal-organic framework films are pyrolyzed to carbon-containing, porous, self-supported anodes of Li ion battery anodes. Scanning electron microscope images indicate that, a layer cobaltosic oxide polyhedrons inserted by the nanowires are obtained with the controllable in-situ synthesis. Thanks to the good dispersion and adherence of cobaltosic oxide polyhedrons on Ti substrates, the self-supported anodes exhibit remarkable rate capability and durability. They possess a capacity of 300 mAh g-1 at a rate current of 20 A g-1, and maintain 2000 charge/discharge cycles without obvious decay.

  5. Transcranial direct current stimulation in mild cognitive impairment: Behavioral effects and neural mechanisms.

    PubMed

    Meinzer, Marcus; Lindenberg, Robert; Phan, Mai Thy; Ulm, Lena; Volk, Carina; Flöel, Agnes

    2015-09-01

    The long preclinical phase of Alzheimer's disease provides opportunities for potential disease-modifying interventions in prodromal stages such as mild cognitive impairment (MCI). Anodal transcranial direct current stimulation (anodal-tDCS), with its potential to enhance neuroplasticity, may allow improving cognition in MCI. In a double-blind, cross-over, sham-controlled study, anodal-tDCS was administered to the left inferior frontal cortex during task-related and resting-state functional magnetic resonance imaging (fMRI) to assess its impact on cognition and brain functions in MCI. During sham stimulation, MCI patients produced fewer correct semantic-word-retrieval responses than matched healthy controls, which was associated with hyperactivity in bilateral prefrontal regions. Anodal-tDCS significantly improved performance to the level of controls, reduced task-related prefrontal hyperactivity and resulted in "normalization" of abnormal network configuration during resting-state fMRI. Anodal-tDCS exerts beneficial effects on cognition and brain functions in MCI, thereby providing a framework to test whether repeated stimulation sessions may yield sustained reversal of cognitive deficits. Copyright © 2015 The Alzheimer's Association. Published by Elsevier Inc. All rights reserved.

  6. CdZnTe Image Detectors for Hard-X-Ray Telescopes

    NASA Technical Reports Server (NTRS)

    Chen, C. M. Hubert; Cook, Walter R.; Harrison, Fiona A.; Lin, Jiao Y. Y.; Mao, Peter H.; Schindler, Stephen M.

    2005-01-01

    Arrays of CdZnTe photodetectors and associated electronic circuitry have been built and tested in a continuing effort to develop focal-plane image sensor systems for hard-x-ray telescopes. Each array contains 24 by 44 pixels at a pitch of 498 m. The detector designs are optimized to obtain low power demand with high spectral resolution in the photon- energy range of 5 to 100 keV. More precisely, each detector array is a hybrid of a CdZnTe photodetector array and an application-specific integrated circuit (ASIC) containing an array of amplifiers in the same pixel pattern as that of the detectors. The array is fabricated on a single crystal of CdZnTe having dimensions of 23.6 by 12.9 by 2 mm. The detector-array cathode is a monolithic platinum contact. On the anode plane, the contact metal is patterned into the aforementioned pixel array, surrounded by a guard ring that is 1 mm wide on three sides and is 0.1 mm wide on the fourth side so that two such detector arrays can be placed side-by-side to form a roughly square sensor area with minimal dead area between them. Figure 1 shows two anode patterns. One pattern features larger pixel anode contacts, with a 30-m gap between them. The other pattern features smaller pixel anode contacts plus a contact for a shaping electrode in the form of a grid that separates all the pixels. In operation, the grid is held at a potential intermediate between the cathode and anode potentials to steer electric charges toward the anode in order to reduce the loss of charges in the inter-anode gaps. The CdZnTe photodetector array is mechanically and electrically connected to the ASIC (see Figure 2), either by use of indium bump bonds or by use of conductive epoxy bumps on the CdZnTe array joined to gold bumps on the ASIC. Hence, the output of each pixel detector is fed to its own amplifier chain.

  7. Electron-Focus Adjustment for Photo-Optical Imagers

    NASA Technical Reports Server (NTRS)

    Fowler, Walter B.; Flemming, Keith; Ziegler, Michael M.

    1987-01-01

    Internal electron focus made independent of optical focus. Procedure enables fine tuning of internal electron-focusing system of photo-optical imager, without complication by imperfections of associated external optics. Applicable to imager in which electrons emitted from photocathode in optical focal plane, then electrostatically and/or magnetically focused to replica of image in second focal plane containing photodiodes, phototransistorss, charge-coupled devices, multiple-anode outputs, or other detectors.

  8. Anodized aluminum pressure sensitive paint for unsteady aerodynamic applications

    NASA Astrophysics Data System (ADS)

    Sakaue, Hirotaka

    2003-06-01

    A comprehensive study of anodized aluminum pressure sensitive paint (AA-PSP) is documented. The study consisted of the development of AA-PSP and its application to unsteady aerodynamic fields at atmospheric conditions. Luminophore application mechanism and two-component application on anodized aluminum was studied for the development. Two-component application includes hydrophobic-coated AA-PSP and bi-luminophore system. It was found that the polarity of solvents and the surface charge of anodized aluminum determine the optimized luminophore application. As a result, a wide variation of luminophore can be applied on anodized aluminum. To apply both components on anodized aluminum, optimum solvent polarities for each component should match. AA-PSP performances, such as pressure sensitivity, temperature dependency, signal level, and aging were improved by the luminophore application mechanism and two-component application. AA-PSPs demonstrate the capability of measuring surface pressures on unsteady aerodynamic fields. For an application to the Purdue Mach 4 Quiet Flow Ludwieg Tube, surface pressures on the order of a hundred Pascals were measured for approximately 200ms. The measurement uncertainty of the pressure was on the order of 5%. The main uncertainty source comes from fitting the adsorption control model to calibration points. The results compared qualitatively well to CFD calculations. A miniature fluidic oscillator was used to demonstrate the capability of measuring oscillating unsteady aerodynamic fields with 6.4kHz primary frequency. Flow oscillation images as well as pressure maps of various phases were captured by AA-PSP with PtTFPP as a luminophore (AA-PSPPtTFPP ). Main uncertainty source comes from fitting the adsorption control model to calibration points and from the pulse width of illumination. The measurement uncertainty of the pressure was 4.68%. AA-PSPPtTFPP was applied to a high-amplified acoustic fielding in a standing wave tube. The maximum pressure change created was 171dB (1.04psi). Sinusoidal pressure wave images inside a standing wave tube were captured at various phases. From these images, the integrated pressure map was obtained. In this case, measurement uncertainty was 3.64% and was due mainly to the pulse width and from fitting of the adsorption controlled model. Comparison with theoretical model is necessary to validate the integrated map as a streaming pattern.

  9. Spatial resolution of imaging plate with flash X-rays and its utilization for radiography

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shaikh, A. M., E-mail: shaikham@barc.gov.in; Romesh, C.; Kolage, T. S.

    2015-06-24

    A flash X-ray source developed using pulsed electron accelerator with electron energy range of 400keV to 1030keV and a field emission cathode is characterized using X-ray imaging plates. Spatial resolution of the imaging system is measured using edge spread function fitted to data obtained from radiograph of Pb step wedge. A spatial resolution of 150±6 µm is obtained. The X-ray beam size is controlled by the anode-cathode configuration. Optimum source size of ∼13±2 mm diameter covering an area with intensity of ∼27000 PSL/mm{sup 2} is obtained on the imaging plate kept at a distance of ∼200 mm from the tip of the anode.more » It is used for recording radiographs of objects like satellite cable cutter, aero-engine turbine blade and variety of pyro-devices used in aerospace industry.« less

  10. Earth Observations taken by Expedition 34 crewmember

    NASA Image and Video Library

    2013-03-12

    ISS034-E-067298 (12 March 2013) --- One of the Expedition 34 crew members aboard the International Space Station recorded this image of much of Galveston Island (right hand two-thirds of the photo), which is annually a popular "spring break" spot for students and vacationers from all over. The activities were just getting started when this photo was made -- about ten days before the "official" start of spring. The west end of Bolivar Peninsula is visible in the lower left quadrant of the image. The Bolivar area looks much different from the way it appeared prior to the devastating Hurricane Ike in September 2008.

  11. High-Resolution Large-Field-of-View Three-Dimensional Hologram Display System and Method Thereof

    NASA Technical Reports Server (NTRS)

    Chao, Tien-Hsin (Inventor); Mintz, Frederick W. (Inventor); Tsou, Peter (Inventor); Bryant, Nevin A. (Inventor)

    2001-01-01

    A real-time, dynamic, free space-virtual reality, 3-D image display system is enabled by using a unique form of Aerogel as the primary display media. A preferred embodiment of this system comprises a 3-D mosaic topographic map which is displayed by fusing four projected hologram images. In this embodiment, four holographic images are projected from four separate holograms. Each holographic image subtends a quadrant of the 4(pi) solid angle. By fusing these four holographic images, a static 3-D image such as a featured terrain map would be visible for 360 deg in the horizontal plane and 180 deg in the vertical plane. An input, either acquired by 3-D image sensor or generated by computer animation, is first converted into a 2-D computer generated hologram (CGH). This CGH is then downloaded into large liquid crystal (LC) panel. A laser projector illuminates the CGH-filled LC panel and generates and displays a real 3-D image in the Aerogel matrix.

  12. An ablative pulsed plasma thruster with a segmented anode

    NASA Astrophysics Data System (ADS)

    Zhang, Zhe; Ren, Junxue; Tang, Haibin; Ling, William Yeong Liang; York, Thomas M.

    2018-01-01

    An ablative pulsed plasma thruster (APPT) design with a ‘segmented anode’ is proposed in this paper. We aim to examine the effect that this asymmetric electrode configuration (a normal cathode and a segmented anode) has on the performance of an APPT. The magnetic field of the discharge arc, plasma density in the exit plume, impulse bit, and thrust efficiency were studied using a magnetic probe, Langmuir probe, thrust stand, and mass bit measurements, respectively. When compared with conventional symmetric parallel electrodes, the segmented anode APPT shows an improvement in the impulse bit of up to 28%. The thrust efficiency is also improved by 49% (from 5.3% to 7.9% for conventional and segmented designs, respectively). Long-exposure broadband emission images of the discharge morphology show that compared with a normal anode, a segmented anode results in clear differences in the luminous discharge morphology and better collimation of the plasma. The magnetic probe data indicate that the segmented anode APPT exhibits a higher current density in the discharge arc. Furthermore, Langmuir probe data collected from the central exit plane show that the peak electron density is 75% higher than with conventional parallel electrodes. These results are believed to be fundamental to the physical mechanisms behind the increased impulse bit of an APPT with a segmented electrode.

  13. Measurement of Vibrated Bulk Density of Coke Particle Blends Using Image Texture Analysis

    NASA Astrophysics Data System (ADS)

    Azari, Kamran; Bogoya-Forero, Wilinthon; Duchesne, Carl; Tessier, Jayson

    2017-09-01

    A rapid and nondestructive machine vision sensor was developed for predicting the vibrated bulk density (VBD) of petroleum coke particles based on image texture analysis. It could be used for making corrective adjustments to a paste plant operation to reduce green anode variability (e.g., changes in binder demand). Wavelet texture analysis (WTA) and gray level co-occurrence matrix (GLCM) algorithms were used jointly for extracting the surface textural features of coke aggregates from images. These were correlated with the VBD using partial least-squares (PLS) regression. Coke samples of several sizes and from different sources were used to test the sensor. Variations in the coke surface texture introduced by coke size and source allowed for making good predictions of the VBD of individual coke samples and mixtures of them (blends involving two sources and different sizes). Promising results were also obtained for coke blends collected from an industrial-baked carbon anode manufacturer.

  14. Investigation of CuInSe2 nanowire arrays with core-shell structure electrodeposited at various duty cycles into anodic alumina templates

    NASA Astrophysics Data System (ADS)

    Cheng, Yu-Song; Wang, Na-Fu; Tsai, Yu-Zen; Lin, Jia-Jun; Houng, Mau-Phon

    2017-02-01

    Copper indium selenide (CuInSe2) nanowire (NW) arrays were prepared at various electrolyte duty cycles by filling anodic alumina templates through the pulsed electrodeposition technique. X-ray diffraction and scanning electron microscopy (SEM) images showed that the nucleation mechanism of CuInSe2 NW arrays was affected by the electrodeposition duty cycle. Moreover, SEM images showed that the diameter and length of the NWs were 80 nm and 2 μm, respectively. Furthermore, PEDOT/CuInSe2 NW core-shell arrays were fabricated using surfactant-modified CuInSe2 NW surfaces showing the lotus effect. Transmission electron microscopy images confirmed that a core-shell structure was achieved. Current-voltage plots revealed that the CuInSe2 NW arrays were p-type semiconductors; moreover, the core-shell structure improved the diode ideality factor from 3.91 to 2.63.

  15. Detection of primary angle closure using anterior segment optical coherence tomography in Asian eyes.

    PubMed

    Nolan, Winifred P; See, Jovina L; Chew, Paul T K; Friedman, David S; Smith, Scott D; Radhakrishnan, Sunita; Zheng, Ce; Foster, Paul J; Aung, Tin

    2007-01-01

    To evaluate noncontact anterior segment optical coherence technology (AS-OCT) as a qualitative method of imaging the anterior chamber angle and to determine its ability to detect primary angle closure when compared with gonioscopy in Asian subjects. Prospective observational case series. Two hundred three subjects were recruited from glaucoma clinics in Singapore with diagnoses of primary angle closure, primary open-angle glaucoma, ocular hypertension, or cataract. Both eyes (if eligible) of each patient were included in the study. Exclusion criteria were pseudophakia or previous glaucoma surgery. Images of the nasal, temporal, and inferior angles were obtained with AS-OCT in dark and then light conditions. Gonioscopic angle width was graded using the Spaeth classification for each quadrant in low lighting conditions. Angle closure was defined by AS-OCT as contact between the peripheral iris and angle wall anterior to the scleral spur and by gonioscopy as a Spaeth grade of 0 degree (posterior trabecular meshwork not visible). Comparison of the 2 methods in detecting angle closure was done by eye and by individual. Sensitivities and specificities of AS-OCT were calculated using gonioscopy as the reference standard. Complete data were available for 342 eyes of 200 patients. Of the patients, 70.9% had a clinical diagnosis of treated or untreated primary angle closure. Angle closure in > or =1 quadrants was detected by AS-OCT in 142 (71%) patients (228 [66.7%] eyes) and by gonioscopy in 99 (49.5%) patients (152 [44.4%] eyes). The inferior angle was closed more frequently than the nasal or temporal quadrants using both AS-OCT and gonioscopy. When performed under dark conditions, AS-OCT identified 98% of those subjects found to have angle closure on gonioscopy (95% confidence interval [CI], 92.2-99.6) and led to the characterization of 44.6% of those found to have open angles on gonioscopy to have angle closure as well. With gonioscopy as the reference standard, specificity of AS-OCT in the dark was 55.4% (95% CI, 45.2-65.2) for detecting individuals with angle closure. Anterior segment OCT is a rapid noncontact method of imaging angle structures. It is highly sensitive in detecting angle closure when compared with gonioscopy. More persons are found to have closed angles with AS-OCT than with gonioscopy.

  16. Dynamic CT for parathyroid disease: are multiple phases necessary?

    PubMed

    Raghavan, P; Durst, C R; Ornan, D A; Mukherjee, S; Wintermark, M; Patrie, J T; Xin, W; Shada, A L; Hanks, J B; Smith, P W

    2014-10-01

    A 4D CT protocol for detection of parathyroid lesions involves obtaining unenhanced, arterial, early, and delayed venous phase images. The aim of the study was to determine the ideal combination of phases that would minimize radiation dose without sacrificing diagnostic accuracy. With institutional review board approval, the records of 29 patients with primary hyperparathyroidism who had undergone surgical exploration were reviewed. Four neuroradiologists who were blinded to the surgical outcome reviewed the imaging studies in 5 combinations (unenhanced and arterial phase; unenhanced, arterial, and early venous; all 4 phases; arterial alone; arterial and early venous phases) with an interval of at least 7 days between each review. The accuracy of interpretation in lateralizing an abnormality to the side of the neck (right, left, ectopic) and localizing it to a quadrant in the neck (right or left upper, right or left lower) was evaluated. The lateralization and localization accuracy (90.5% and 91.5%, respectively) of the arterial phase alone was comparable with the other combinations of phases. There was no statistically significant difference among the different combinations of phases in their ability to lateralize or localize adenomas to a quadrant (P = .976 and .996, respectively). Assessment of a small group of patients shows that adequate diagnostic accuracy for parathyroid adenoma localization may be achievable by obtaining arterial phase images alone. If this outcome can be validated prospectively in a larger group of patients, then the radiation dose can potentially be reduced to one-fourth of what would otherwise be administered. © 2014 by American Journal of Neuroradiology.

  17. Brain and behaviour phenotyping of a mouse model of neurofibromatosis type-1: an MRI/DTI study on social cognition.

    PubMed

    Petrella, L I; Cai, Y; Sereno, J V; Gonçalves, S I; Silva, A J; Castelo-Branco, M

    2016-09-01

    Neurofibromatosis type-1 (NF1) is a common neurogenetic disorder and an important cause of intellectual disability. Brain-behaviour associations can be examined in vivo using morphometric magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI) to study brain structure. Here, we studied structural and behavioural phenotypes in heterozygous Nf1 mice (Nf1(+/-) ) using T2-weighted imaging MRI and DTI, with a focus on social recognition deficits. We found that Nf1(+/-) mice have larger volumes than wild-type (WT) mice in regions of interest involved in social cognition, the prefrontal cortex (PFC) and the caudate-putamen (CPu). Higher diffusivity was found across a distributed network of cortical and subcortical brain regions, within and beyond these regions. Significant differences were observed for the social recognition test. Most importantly, significant structure-function correlations were identified concerning social recognition performance and PFC volumes in Nf1(+/-) mice. Analyses of spatial learning corroborated the previously known deficits in the mutant mice, as corroborated by platform crossings, training quadrant time and average proximity measures. Moreover, linear discriminant analysis of spatial performance identified 2 separate sub-groups in Nf1(+/-) mice. A significant correlation between quadrant time and CPu volumes was found specifically for the sub-group of Nf1(+/-) mice with lower spatial learning performance, suggesting additional evidence for reorganization of this region. We found strong evidence that social and spatial cognition deficits can be associated with PFC/CPu structural changes and reorganization in NF1. © 2016 John Wiley & Sons Ltd and International Behavioural and Neural Genetics Society.

  18. Breakthrough in 4π ion emission mechanism understanding in plasma focus devices.

    PubMed

    Sohrabi, Mehdi; Zarinshad, Arefe; Habibi, Morteza

    2016-12-12

    Ion emission angular distribution mechanisms in plasma focus devices (PFD) have not yet been well developed and understood being due to the lack of an efficient wide-angle ion distribution image detection system to characterize a PFD space in detail. Present belief is that the acceleration of ions points from "anode top" upwards in forward direction within a small solid angle. A breakthrough is reported in this study, by mega-size position-sensitive polycarbonate ion image detection systems invented, on discovery of 4π ion emission from the "anode top" in a PFD space after plasma pinch instability and radial run-away of ions from the "anode cathodes array" during axial acceleration of plasma sheaths before the radial phase. These two ion emission source mechanisms behave respectively as a "Point Ion Source" and a "Line Ion Source" forming "Ion Cathode Shadows" on mega-size detectors. We believe that the inventions and discoveries made here will open new horizons for advanced ion emission studies towards better mechanisms understanding and in particular will promote efficient applications of PFDs in medicine, science and technology.

  19. EIT: Solar corona synoptic observations from SOHO with an Extreme-ultraviolet Imaging Telescope

    NASA Technical Reports Server (NTRS)

    Delaboudiniere, J. P.; Gabriel, A. H.; Artzner, G. E.; Michels, D. J.; Dere, K. P.; Howard, R. A.; Catura, R.; Stern, R.; Lemen, J.; Neupert, W.

    1988-01-01

    The Extreme-ultraviolet Imaging Telescope (EIT) of SOHO (solar and heliospheric observatory) will provide full disk images in emission lines formed at temperatures that map solar structures ranging from the chromospheric network to the hot magnetically confined plasma in the corona. Images in four narrow bandpasses will be obtained using normal incidence multilayered optics deposited on quadrants of a Ritchey-Chretien telescope. The EIT is capable of providing a uniform one arc second resolution over its entire 50 by 50 arc min field of view. Data from the EIT will be extremely valuable for identifying and interpreting the spatial and temperature fine structures of the solar atmosphere. Temporal analysis will provide information on the stability of these structures and identify dynamical processes. EIT images, issued daily, will provide the global corona context for aid in unifying the investigations and in forming the observing plans for SOHO coronal instruments.

  20. CapDEM TD - Modeling and Simulation (Role and Tools) State of the Art Report

    DTIC Science & Technology

    2005-01-01

    office/wcm1/ornclinfn/ciefilnlt rnsnx [55] http://www.idefine.com/Tutorial/TutOiial%20Sales%20Page.htm [56] Gartner , " Magic Quadrant for Business ...21 Figure 3-5: Gartner Magic Quadrant For BPA, 2004 (56...of January 2004 Niche Players Visionaries ------- Completeness of Vision ..., Figure 3-5: Gartner Magic Quadrant For BPA, 2004 [56] Gartner , Inc

  1. Water management in a planar air-breathing fuel cell array using operando neutron imaging

    NASA Astrophysics Data System (ADS)

    Coz, E.; Théry, J.; Boillat, P.; Faucheux, V.; Alincant, D.; Capron, P.; Gébel, G.

    2016-11-01

    Operando Neutron imaging is used for the investigation of a planar air-breathing array comprising multiple cells in series. The fuel cell demonstrates a stable power density level of 150 mW/cm2. Water distribution and quantification is carried out at different operating points. Drying at high current density is observed and correlated to self-heating and natural convection. Working in dead-end mode, water accumulation at lower current density is largely observed on the anode side. However, flooding mechanisms are found to begin with water condensation on the cathode side, leading to back-diffusion and anodic flooding. Specific in-plane and through-plane water distribution is observed and linked to the planar array design.

  2. Design and experimental research on a self-magnetic pinch diode under MV

    NASA Astrophysics Data System (ADS)

    Pengfei, ZHANG; Yang, HU; Jiang, SUN; Yan, SONG; Jianfeng, SUN; Zhiming, YAO; Peitian, CONG; Mengtong, QIU; Aici, QIU

    2018-01-01

    A self-magnetic pinch diode (SMPD) integrating an anode foil-reinforced electron beam pinch focus and a small high-dose x-ray spot output was designed and optimized. An x-ray focal spot measuring system was developed in accordance with the principle of pinhole imaging. The designed SMPD and the corresponding measuring system were tested under ∼MV, with 1.75 × 2 mm2 oval x-ray spots (AWE defined) and forward directed dose 1.6 rad at 1 m. Results confirmed that the anode foil can significantly strengthen the electron beam pinch focus, and the focal spot measuring system can collect clear focal spot images. This finding indicated that the principle and method are feasible.

  3. Region-based multi-step optic disk and cup segmentation from color fundus image

    NASA Astrophysics Data System (ADS)

    Xiao, Di; Lock, Jane; Manresa, Javier Moreno; Vignarajan, Janardhan; Tay-Kearney, Mei-Ling; Kanagasingam, Yogesan

    2013-02-01

    Retinal optic cup-disk-ratio (CDR) is a one of important indicators of glaucomatous neuropathy. In this paper, we propose a novel multi-step 4-quadrant thresholding method for optic disk segmentation and a multi-step temporal-nasal segmenting method for optic cup segmentation based on blood vessel inpainted HSL lightness images and green images. The performance of the proposed methods was evaluated on a group of color fundus images and compared with the manual outlining results from two experts. Dice scores of detected disk and cup regions between the auto and manual results were computed and compared. Vertical CDRs were also compared among the three results. The preliminary experiment has demonstrated the robustness of the method for automatic optic disk and cup segmentation and its potential value for clinical application.

  4. Calibration of the island effect: Experimental validation of closed-loop focal plane wavefront control on Subaru/SCExAO

    NASA Astrophysics Data System (ADS)

    N'Diaye, M.; Martinache, F.; Jovanovic, N.; Lozi, J.; Guyon, O.; Norris, B.; Ceau, A.; Mary, D.

    2018-02-01

    Context. Island effect (IE) aberrations are induced by differential pistons, tips, and tilts between neighboring pupil segments on ground-based telescopes, which severely limit the observations of circumstellar environments on the recently deployed exoplanet imagers (e.g., VLT/SPHERE, Gemini/GPI, Subaru/SCExAO) during the best observing conditions. Caused by air temperature gradients at the level of the telescope spiders, these aberrations were recently diagnosed with success on VLT/SPHERE, but so far no complete calibration has been performed to overcome this issue. Aims: We propose closed-loop focal plane wavefront control based on the asymmetric Fourier pupil wavefront sensor (APF-WFS) to calibrate these aberrations and improve the image quality of exoplanet high-contrast instruments in the presence of the IE. Methods: Assuming the archetypal four-quadrant aperture geometry in 8 m class telescopes, we describe these aberrations as a sum of the independent modes of piston, tip, and tilt that are distributed in each quadrant of the telescope pupil. We calibrate these modes with the APF-WFS before introducing our wavefront control for closed-loop operation. We perform numerical simulations and then experimental tests on a real system using Subaru/SCExAO to validate our control loop in the laboratory and on-sky. Results: Closed-loop operation with the APF-WFS enables the compensation for the IE in simulations and in the laboratory for the small aberration regime. Based on a calibration in the near infrared, we observe an improvement of the image quality in the visible range on the SCExAO/VAMPIRES module with a relative increase in the image Strehl ratio of 37%. Conclusions: Our first IE calibration paves the way for maximizing the science operations of the current exoplanet imagers. Such an approach and its results prove also very promising in light of the Extremely Large Telescopes (ELTs) and the presence of similar artifacts with their complex aperture geometry.

  5. Splenic Infarction in Acute Infectious Mononucleosis.

    PubMed

    Naviglio, Samuele; Abate, Maria Valentina; Chinello, Matteo; Ventura, Alessandro

    2016-01-01

    The evaluation of a febrile patient with acute abdominal pain represents a frequent yet possibly challenging situation in the emergency department (ED). Splenic infarction is an uncommon complication of infectious mononucleosis, and may have a wide range of clinical presentations, from dramatic to more subtle. Its pathogenesis is still incompletely understood, yet it may be associated with the occurrence of transient prothrombotic factors. We report the case of a 14-year-old boy who presented with fever, sore throat, left upper quadrant abdominal pain, and splenomegaly, with no history of recent trauma. Laboratory tests revealed a markedly prolonged activated partial thromboplastin time and positive lupus anticoagulant. Abdominal ultrasonography showed several hypoechoic areas in the spleen consistent with multiple infarctions. Magnetic resonance imaging eventually confirmed the diagnosis. He was admitted for observation and supportive treatment, and was discharged in good condition after 7 days. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: Spontaneous splenic infarction should be considered in the differential list of patients presenting with left upper quadrant abdominal pain and features of infectious mononucleosis; the diagnosis, however, may not be straightforward, as clinical presentation may also be subtle, and abdominal ultrasonography, which is often used as a first-line imaging modality in pediatric EDs, has low sensitivity in this scenario and may easily miss it. Furthermore, although treatment is mainly supportive, close observation for possible complications is necessary. Copyright © 2016 Elsevier Inc. All rights reserved.

  6. Deuteron injector for Peking University Neutron Imaging Facility projecta)

    NASA Astrophysics Data System (ADS)

    Ren, H. T.; Peng, S. X.; Lu, P. N.; Zhou, Q. F.; Yuan, Z. X.; Zhao, J.; Zhang, M.; Song, Z. Z.; Yu, J. X.; Guo, Z. Y.; Chen, J. E.

    2012-02-01

    The deuteron injector developed for the PKUNIFTY (Peking University Neutron Imaging Facility) has been installed and commissioned at Peking University (PKU). The injector system must transfer 50 keV 50 mA of D+ ion beam to the entrance of the 2 MeV radio frequency quadrupole (RFQ) with 10% duty factor (1 ms, 100 Hz). A compact 2.45 GHz permanent magnet electron cyclotron resonance (PMECR) ion source and a 1.36 m long low energy beam transport (LEBT) line using two solenoids was developed as the deuteron injector. A ϕ5 mm four-quadrant diaphragm was used to simulate the entrance of RFQ electrodes. The beam parameters are measured after this core with an emittance measurement unit (EMU) and a bending magnet for ion fraction analysis at the end of injector. During the commissioning, 77 mA of total deuteron beam was extracted from PMECR and 56 mA of pure D+ beam that passed through the ϕ5 mm four-quadrant diaphragm was obtained at the position of RFQ entrance with the measured normalized rms emittance 0.12-0.16π mm mrad. Ion species analysis results show that the deuteron fraction is as high as 99.5%. All of the parameters satisfy PKUNIFTY's requirements. In this paper, we will describe the deuteron injector design and report the commissioning results as well as the initial operation.

  7. A survey on the utilization of disposable quadrant articulators.

    PubMed

    Thornton, Linda J

    2002-01-01

    This study evaluated utilization of the six most popular disposable quadrant articulators presently used in crown fabrication. Most general practitioners and crown and bridge laboratory technicians reported that they frequently or always used disposable quadrant articulators for single units and simple three-unit fixed partial dentures. All evaluated articulators demonstrated an inability to maintain and repeat the centric stop position. The disposable quadrant articulator, used in combination with dual-arch impressions, is a viable method for fabricating single and short-span restorations. While a nonrepeatable centric stop was present in all six articulators evaluated, the method was considered a time-efficient and cost-saving alternative to traditional all-metal simple-hinge articulators.

  8. Quadrant CFD Analysis of a Mixer-Ejector Nozzle for HSCT Applications

    NASA Technical Reports Server (NTRS)

    Yoder, Dennis A.; Georgiadis, Nicholas J.; Wolter, John D.

    2005-01-01

    This study investigates the sidewall effect on flow within the mixing duct downstream of a lobed mixer-ejector nozzle. Simulations which model only one half-chute width of the ejector array are compared with those which model one complete quadrant of the nozzle geometry and with available experimental data. These solutions demonstrate the applicability of the half-chute technique to model the flowfield far away from the sidewall and the necessity of a full-quadrant simulation to predict the formation of a low-energy flow region near the sidewall. The quadrant solutions are further examined to determine the cause of this low-energy region, which reduces the amount of mixing and lowers the thrust of the nozzle. Grid resolution and different grid topologies are also examined. Finally, an assessment of the half-chute and quadrant approaches is made to determine the ability of these simulations to provide qualitative and/or quantitative predictions for this type of complex flowfield.

  9. Enzymatic Fuel Cells: Integrating Flow-Through Anode and Air-Breathing Cathode into a Membrane-Less Biofuel Cell Design (Postprint)

    DTIC Science & Technology

    2011-06-01

    AFRL-RX-TY-TP-2011-0081 ENZYMATIC FUEL CELLS: INTEGRATING FLOW- THROUGH ANODE AND AIR-BREATHING CATHODE INTO A MEMBRANE-LESS BIOFUEL CELL...RESPONSIBLE PERSON 19b. TELEPHONE NUMBER (Include area code) 01-JUN-2011 Journal Article (POSTPRINT) 01-JAN-2010 -- 31-JAN-2011 Enzymatic Fuel Cells...unlimited. Ref Public Affairs Case # 88ABW-2011-2228, 14 Apr 11. Document contains color images. One of the key goals of enzymatic biofuel cells

  10. The phonatory deviation diagram: a novel objective measurement of vocal function.

    PubMed

    Madazio, Glaucya; Leão, Sylvia; Behlau, Mara

    2011-01-01

    To identify the discriminative characteristics of the phonatory deviation diagram (PDD) in rough, breathy and tense voices. One hundred and ninety-six samples of normal and dysphonic voices from adults were submitted to perceptual auditory evaluation, focusing on the predominant vocal quality and the degree of deviation. Acoustic analysis was performed with the VoxMetria (CTS Informatica). Significant differences were observed between the dysphonic and normal groups (p < 0.001), and also between the breathy and rough samples (p = 0.044) and the breathy and tense samples (p < 0.001). All normal voices were positioned in the inferior left quadrant, 45% of the rough voices in the inferior right quadrant, 52.6% of the breathy voices in the superior right quadrant and 54.3% of the tense voices in the inferior left quadrant of the PDD. In the inferior left quadrant, 93.8% of voices with no deviation were located and 72.7% of voices with mild deviation; voices with moderate deviation were distributed in the inferior and superior right quadrants, the latter ones containing the most deviant voices and 80% of voices with severe deviation. The PDD was able to discriminate normal from dysphonic voices, and the distribution was related to the type and degree of voice alteration. Copyright © 2011 S. Karger AG, Basel.

  11. Conduction velocity of the uterine contraction in serial magnetomyogram (MMG) data: event based simulation and validation.

    PubMed

    Furdea, Adrian; Preissl, Hubert; Lowery, Curtis L; Eswaran, Hari; Govindan, Rathinaswamy B

    2011-01-01

    We propose a novel approach to calculate the conduction velocity (CV) of the uterine contraction bursts in magnetomyogram (MMG) signals measured using a multichannel SQUID array. For this purpose, we partition the sensor coordinates into four different quadrants and identify the contractile bursts using a previously proposed Hilbert-wavelet transform approach. If contractile burst is identified in more than one quadrant, we calculate the center of gravity (CoG) in each quadrant for each time point as the sum of the product of the sensor coordinates with the Hilbert amplitude of the MMG signals normalized by the sum of the Hilbert amplitude of the signals over all sensors. Following this we compute the delay between the CoGs of all (six) possible quadrant pairs combinations. As a first step, we validate this approach by simulating a stochastic model based on independent second-order autoregressive processes (AR2) and we divide them into 30 second disjoint windows and insert burst activity at specific time instances in preselected sensors. Also we introduce a lag of 5 ± 1 seconds between different quadrants. Using our approach we calculate the CoG of the signals in a quadrant. To this end, we compute the delay between CoGs obtained from different quadrants and show that our approach is able to reliably capture the delay incorporated in the model. We apply the proposed approach to 19 serial MMG data obtained from two subjects and show an increase in the CV as the subjects approached labor.

  12. Applying the balanced scorecard to local public health performance measurement: deliberations and decisions

    PubMed Central

    Weir, Erica; d'Entremont, Nadine; Stalker, Shelley; Kurji, Karim; Robinson, Victoria

    2009-01-01

    Background All aspects of the heath care sector are being asked to account for their performance. This poses unique challenges for local public health units with their traditional focus on population health and their emphasis on disease prevention, health promotion and protection. Reliance on measures of health status provides an imprecise and partial picture of the performance of a health unit. In 2004 the provincial Institute for Clinical Evaluative Sciences based in Ontario, Canada introduced a public-health specific balanced scorecard framework. We present the conceptual deliberations and decisions undertaken by a health unit while adopting the framework. Discussion Posing, pondering and answering key questions assisted in applying the framework and developing indicators. Questions such as: Who should be involved in developing performance indicators? What level of performance should be measured? Who is the primary intended audience? Where and how do we begin? What types of indicators should populate the health status and determinants quadrant? What types of indicators should populate the resources and services quadrant? What type of indicators should populate the community engagement quadrant? What types of indicators should populate the integration and responsiveness quadrants? Should we try to link the quadrants? What comparators do we use? How do we move from a baseline report card to a continuous quality improvement management tool? Summary An inclusive, participatory process was chosen for defining and creating indicators to populate the four quadrants. Examples of indicators that populate the four quadrants of the scorecard are presented and key decisions are highlighted that facilitated the process. PMID:19426508

  13. Applying the balanced scorecard to local public health performance measurement: deliberations and decisions.

    PubMed

    Weir, Erica; d'Entremont, Nadine; Stalker, Shelley; Kurji, Karim; Robinson, Victoria

    2009-05-08

    All aspects of the heath care sector are being asked to account for their performance. This poses unique challenges for local public health units with their traditional focus on population health and their emphasis on disease prevention, health promotion and protection. Reliance on measures of health status provides an imprecise and partial picture of the performance of a health unit. In 2004 the provincial Institute for Clinical Evaluative Sciences based in Ontario, Canada introduced a public-health specific balanced scorecard framework. We present the conceptual deliberations and decisions undertaken by a health unit while adopting the framework. Posing, pondering and answering key questions assisted in applying the framework and developing indicators. Questions such as: Who should be involved in developing performance indicators? What level of performance should be measured? Who is the primary intended audience? Where and how do we begin? What types of indicators should populate the health status and determinants quadrant? What types of indicators should populate the resources and services quadrant? What type of indicators should populate the community engagement quadrant? What types of indicators should populate the integration and responsiveness quadrants? Should we try to link the quadrants? What comparators do we use? How do we move from a baseline report card to a continuous quality improvement management tool? An inclusive, participatory process was chosen for defining and creating indicators to populate the four quadrants. Examples of indicators that populate the four quadrants of the scorecard are presented and key decisions are highlighted that facilitated the process.

  14. Microphysical Structures of Hurricane Irma Observed by Polarimetric Radar

    NASA Astrophysics Data System (ADS)

    Didlake, A. C.; Kumjian, M. R.

    2017-12-01

    This study examines dual-polarization radar observations of Hurricane Irma as its center passed near the WSR-88D radar in Puerto Rico, capturing needed microphysical information of a mature tropical cyclone. Twenty hours of observations continuously sampled the inner core precipitation features. These data were analyzed by annuli and azimuth, providing a bulk characterization of the primary eyewall, secondary eyewall, and rainbands as they varied around the storm. Polarimetric radar variables displayed distinct signatures of convective and stratiform precipitation in the primary eyewall and rainbands that were organized in a manner consistent with the expected kinematic asymmetry of a storm in weak environmental wind shear but with moderate low-level storm-relative flow. In the front quadrants of the primary eyewall, vertical profiles of differential reflectivity (ZDR) exhibit increasing values with decreasing height consistent with convective precipitation processes. In particular, the front-right quadrant exhibits a signature in reflectivity (ZH) and ZDR indicating larger, sparser drops, which is consistent with a stronger updraft present in this quadrant. In the rear quadrants, a sharply peaked ZDR maximum occurs within the melting layer, which is attributed of stratiform processes. In the rainbands, the convective to stratiform transition can be seen traveling from the front-right to the front-left quadrant. The front-right quadrant exhibits lower co-polar correlation coefficient (ρHV) values in the 3-8 km altitude layer, suggesting larger vertical spreading of various hydrometeors that occurs in convective vertical motions. The front-left quadrant exhibits larger ρHV values, suggesting less diversity of hydrometeor shapes, consistent with stratiform processes. The secondary eyewall did not exhibit a clear signature of processes preferred in a specific quadrant, and a temporal analysis of the secondary eyewall revealed a complex evolution of its structure. These results provide important microphysical insight that are critical for understanding the inner core processes modulating tropical cyclone intensity and structure.

  15. Multi-Quadrant Biopsy Technique Improves Diagnostic Ability in Large Heterogeneous Renal Masses.

    PubMed

    Abel, E Jason; Heckman, Jennifer E; Hinshaw, Louis; Best, Sara; Lubner, Meghan; Jarrard, David F; Downs, Tracy M; Nakada, Stephen Y; Lee, Fred T; Huang, Wei; Ziemlewicz, Timothy

    2015-10-01

    Percutaneous biopsy obtained from a single location is prone to sampling error in large heterogeneous renal masses, leading to nondiagnostic results or failure to detect poor prognostic features. We evaluated the accuracy of percutaneous biopsy for large renal masses using a modified multi-quadrant technique vs a standard biopsy technique. Clinical and pathological data for all patients with cT2 or greater renal masses who underwent percutaneous biopsy from 2009 to 2014 were reviewed. The multi-quadrant technique was defined as multiple core biopsies from at least 4 separate solid enhancing areas in the tumor. The incidence of nondiagnostic findings, sarcomatoid features and procedural complications was recorded, and concordance between biopsy specimens and nephrectomy pathology was compared. A total of 122 biopsies were performed for 117 tumors in 116 patients (46 using the standard biopsy technique and 76 using the multi-quadrant technique). Median tumor size was 10 cm (IQR 8-12). Biopsy was nondiagnostic in 5 of 46 (10.9%) standard and 0 of 76 (0%) multi-quadrant biopsies (p=0.007). Renal cell carcinoma was identified in 96 of 115 (82.0%) tumors and nonrenal cell carcinoma tumors were identified in 21 (18.0%). One complication occurred using the standard biopsy technique and no complications were reported using the multi-quadrant technique. Sarcomatoid features were present in 23 of 96 (23.9%) large renal cell carcinomas studied. Sensitivity for identifying sarcomatoid features was higher using the multi-quadrant technique compared to the standard biopsy technique at 13 of 15 (86.7%) vs 2 of 8 (25.0%) (p=0.0062). The multi-quadrant percutaneous biopsy technique increases the ability to identify aggressive pathological features in large renal tumors and decreases nondiagnostic biopsy rates. Copyright © 2015 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

  16. Characterization of the Hamamatsu H12700A-03 and R12699-03 multi-anode photomultiplier tubes

    NASA Astrophysics Data System (ADS)

    Calvi, M.; Carniti, P.; Cassina, L.; Gotti, C.; Maino, M.; Matteuzzi, C.; Pessina, G.

    2015-09-01

    The H12700 is a novel 64-channel 52 × 52 mm2 square Multi-Anode PhotoMultiplier Tube (MaPMT) produced by Hamamatsu. Its characteristics make this device suitable for high energy physics applications, such as in Ring Imaging Cherenkov (RICH) detectors. Hamamatsu provides the H12700 tube with an embedded socket connecting the anodes to the output pins and including an active voltage divider. A second device version, the R12699, is also available and differs from the former by the absence of the socket. This paper describes a complete characterization of both models, starting from the standard operating parameters (single photon spectra, average gain, anode uniformity and dark current value), investigating in detail the cross-talk effect among neighbouring pixels and considering the behaviour in critical environment conditions, such as in presence of a static magnetic field up to 100 Gauss, at different operating temperatures and after long exposure to intense light.

  17. Scanning electron microscopy of heat treated TiO2 nanotubes arrays obtained by anodic oxidation

    NASA Astrophysics Data System (ADS)

    Naranjo, D. I.; García-Vergara, S. J.; Blanco, S.

    2017-12-01

    Scanning electron microscopy was used to investigate the anatase-rutile transformation of self-organized TiO2 nanotubes obtained on titanium foil by anodizing and subsequent heat treatment. The anodizing was carried out at 20V in an 1% v/v HF acid and ethylene glycol:water (50:50) electrolyte at room temperature. The anodized samples were initially pre-heat treated at 450°C for 4 hours to modify the amorphous structure of TiO2 nanotubes into anatase structure. Then, the samples were heated between 600 to 800°C for different times, in order to promote the transformation to rutile structure. The formation of TiO2 nanotubes is evident by SEM images. Notably, when the samples are treated at high temperature, the formation of rutile crystals starts to become evident at the nanotubes located on the originally grain boundaries of the titanium. Thus, the anatase - rutile transformation has a close relationship with the microstructure of the titanium, more exactly with grain boundaries.

  18. SiC Nanofibers as Long-Life Lithium-Ion Battery Anode Materials.

    PubMed

    Sun, Xuejiao; Shao, Changzhen; Zhang, Feng; Li, Yi; Wu, Qi-Hui; Yang, Yonggang

    2018-01-01

    The development of high energy lithium-ion batteries (LIBs) has spurred the designing and production of novel anode materials to substitute currently commercial using graphitic materials. Herein, twisted SiC nanofibers toward LIBs anode materials, containing 92.5 wt% cubic β-SiC and 7.5 wt% amorphous C, were successfully synthesized from resin-silica composites. The electrochemical measurements showed that the SiC-based electrode delivered a stable reversible capacity of 254.5 mAh g -1 after 250 cycles at a current density of 0.1 A g -1 . It is interesting that a high discharge capacity of 540.1 mAh g -1 was achieved after 500 cycles at an even higher current density of 0.3 A g -1 , which is higher than the theoretical capacity of graphite. The results imply that SiC nanomaterials are potential anode candidate for LIBs with high stability due to their high structure stability as supported with the transmission electron microscopy images.

  19. Mechanical characterization and modeling for anodes and cathodes in lithium-ion batteries

    NASA Astrophysics Data System (ADS)

    Wang, Lubing; Yin, Sha; Zhang, Chao; Huan, Yong; Xu, Jun

    2018-07-01

    Mechanical properties of electrode materials have significant influence over electrochemical properties as well as mechanical integrity of lithium-ion battery cells. Here, anode and cathode in a commercially available 18650 NCA (Nickel Cobalt Aluminum Oxide)/graphite cell were comprehensively studied by tensile tests considering material anisotropy, SOC (state of charge), strain rate and electrolyte content. Results showed that the mechanical properties of both electrodes were highly dependent on strain rate and electrolyte content; however, anode was SOC dependent while cathode was not. Besides, coupled effects of strain rate and SOC of anodes were also discussed. SEM (scanning electron microscope) images of surfaces and cross-sections of electrodes showed the fracture morphology. In addition, mechanical behavior of Cu foil separated from anode with different SOC values were studied and compared. Finally, constitutive models of electrodes considering both strain rate and anisotropy effects were established. This study reveals the relationship between electrochemical dependent mechanical behavior of the electrodes. The established mechanical models of electrodes can be applied to the numerical computation of battery cells. Results are essential to predict the mechanical responses as well as the deformation of battery cell under various loading conditions, facilitating safer battery design and manufacturing.

  20. Investigation of mechanism of anode plasma formation in ion diode with dielectric anode

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pushkarev, A., E-mail: aipush@mail.ru

    The results of investigation of the anode plasma formation in a diode with a passive anode in magnetic insulation mode are presented. The experiments have been conducted using the BIPPAB-450 ion accelerator (350–400 kV, 6–8 kA, 80 ns) with a focusing conical diode with B{sub r} external magnetic field (a barrel diode). For analysis of plasma formation at the anode and the distribution of the ions beam energy density, infrared imaging diagnostics (spatial resolution of 1–2 mm) is used. For analysis of the ion beam composition, time-of-flight diagnostics (temporal resolution of 1 ns) were used. Our studies have shown that when the magnetic induction inmore » the A-C gap is much larger than the critical value, the ion beam energy density is close to the one-dimensional Child-Langmuir limit on the entire working surface of the diode. Formation of anode plasma takes place only by the flashover of the dielectric anode surface. In this mode, the ion beam consists primarily of singly ionized carbon ions, and the delay of the start of formation of the anode plasma is 10–15 ns. By reducing the magnetic induction in the A-C gap to a value close to the critical one, the ion beam energy density is 3–6 times higher than that calculated by the one-dimensional Child-Langmuir limit, but the energy density of the ion beam is non-uniform in cross-section. In this mode, the anode plasma formation occurs due to ionization of the anode material with accelerated electrons. In this mode, also, the delay in the start of the formation of the anode plasma is much smaller and the degree of ionization of carbon ions is higher. In all modes occurred effective suppression of the electronic component of the total current, and the diode impedance was 20–30 times higher than the values calculated for the mode without magnetic insulation of the electrons. The divergence of the ion beam was 4.5°–6°.« less

  1. Ultra-low noise large-area InGaAs quad photoreceiver with low crosstalk for laser interferometry space antenna

    NASA Astrophysics Data System (ADS)

    Joshi, Abhay; Datta, Shubhashish; Rue, Jim; Livas, Jeffrey; Silverberg, Robert; Guzman Cervantes, Felipe

    2012-07-01

    Quad photoreceivers, namely a 2 x 2 array of p-i-n photodiodes followed by a transimpedance amplifier (TIA) per diode, are required as the front-end photonic sensors in several applications relying on free-space propagation with position and direction sensing capability, such as long baseline interferometry, free-space optical communication, and biomedical imaging. It is desirable to increase the active area of quad photoreceivers (and photodiodes) to enhance the link gain, and therefore sensitivity, of the system. However, the resulting increase in the photodiode capacitance reduces the photoreceiver's bandwidth and adds to the excess system noise. As a result, the noise performance of the front-end quad photoreceiver has a direct impact on the sensitivity of the overall system. One such particularly challenging application is the space-based detection of gravitational waves by measuring distance at 1064 nm wavelength with ~ 10 pm/√Hz accuracy over a baseline of millions of kilometers. We present a 1 mm diameter quad photoreceiver having an equivalent input current noise density of < 1.7 pA/√Hz per quadrant in 2 MHz to 20 MHz frequency range. This performance is primarily enabled by a rad-hard-by-design dualdepletion region InGaAs quad photodiode having 2.5 pF capacitance per quadrant. Moreover, the quad photoreceiver demonstrates a crosstalk of < -45 dB between the neighboring quadrants, which ensures an uncorrected direction sensing resolution of < 50 nrad. The sources of this primarily capacitive crosstalk are presented.

  2. Distinct regions of the hippocampus are associated with memory for different spatial locations.

    PubMed

    Jeye, Brittany M; MacEvoy, Sean P; Karanian, Jessica M; Slotnick, Scott D

    2018-05-15

    In the present functional magnetic resonance imaging (fMRI) study, we aimed to evaluate whether distinct regions of the hippocampus were associated with spatial memory for items presented in different locations of the visual field. In Experiment 1, during the study phase, participants viewed abstract shapes in the left or right visual field while maintaining central fixation. At test, old shapes were presented at fixation and participants classified each shape as previously in the "left" or "right" visual field followed by an "unsure"-"sure"-"very sure" confidence rating. Accurate spatial memory for shapes in the left visual field was isolated by contrasting accurate versus inaccurate spatial location responses. This contrast produced one hippocampal activation in which the interaction between item type and accuracy was significant. The analogous contrast for right visual field shapes did not produce activity in the hippocampus; however, the contrast of high confidence versus low confidence right-hits produced one hippocampal activation in which the interaction between item type and confidence was significant. In Experiment 2, the same paradigm was used but shapes were presented in each quadrant of the visual field during the study phase. Accurate memory for shapes in each quadrant, exclusively masked by accurate memory for shapes in the other quadrants, produced a distinct activation in the hippocampus. A multi-voxel pattern analysis (MVPA) of hippocampal activity revealed a significant correlation between behavioral spatial location accuracy and hippocampal MVPA accuracy across participants. The findings of both experiments indicate that distinct hippocampal regions are associated with memory for different visual field locations. Copyright © 2018 Elsevier B.V. All rights reserved.

  3. Seeing the Hidden Lamina: Effects of Exsanguination on the Optic Nerve Head

    PubMed Central

    Tran, Huong; Wallace, Jacob; Zhu, Ziyi; Lucy, Katie A.; Voorhees, Andrew P.; Schmitt, Samantha E.; Bilonick, Richard A.; Schuman, Joel S.; Smith, Matthew A.; Wollstein, Gadi; Sigal, Ian A.

    2018-01-01

    Purpose To introduce an experimental approach for direct comparison of the primate optic nerve head (ONH) before and after death by exsanguination. Method The ONHs of four eyes from three monkeys were imaged with spectral-domain optical coherence tomography (OCT) before and after exsanguination under controlled IOP. ONH structures, including the Bruch membrane (BM), BM opening, inner limiting membrane (ILM), and anterior lamina cribrosa (ALC) were delineated on 18 virtual radial sections per OCT scan. Thirteen parameters were analyzed: scleral canal at BM opening (area, planarity, and aspect ratio), ILM depth, BM depth; ALC (depth, shape index, and curvedness), and ALC visibility (globally, superior, inferior, nasal, and temporal quadrants). Results All four ALC quadrants had a statistically significant improvement in visibility after exsanguination (overall P < 0.001). ALC visibility increased by 35% globally and by 36%, 37%, 14%, and 4% in the superior, inferior, nasal, and temporal quadrants, respectively. ALC increased 4.1%, 1.9%, and 0.1% in curvedness, shape index, and depth, respectively. Scleral canals increased 7.2%, 25.2%, and 1.1% in area, planarity, and aspect ratio, respectively. ILM and BM depths averaged −7.5% and −55.2% decreases in depth, respectively. Most, but not all, changes were beyond the repeatability range. Conclusions Exsanguination allows for improved lamina characterization, especially in regions typically blocked by shadowing in OCT. The results also demonstrate changes in ONH morphology due to the loss of blood pressure. Future research will be needed to determine whether there are differences in ONH biomechanics before and after exsanguination and what those differences would imply. PMID:29847664

  4. Location, location, location: does early cancer in Barrett's esophagus have a preference?

    PubMed

    Enestvedt, Brintha K; Lugo, Ricardo; Guarner-Argente, Carlos; Shah, Pari; Falk, Gary W; Furth, Emma; Ginsberg, Gregory G

    2013-09-01

    Early cancer (high-grade dysplasia [HGD] and intramucosal carcinoma [ImCa]) associated with Barrett's esophagus (BE) may have a circumferential spatial predilection. To describe the esophageal circumferential location of early cancer in BE. Retrospective study, single tertiary referral center. One hundred nineteen patients were referred for endoscopic eradication therapy for early cancer associated with BE. Endoscopic images and reports and pathology were reviewed. Circumferential location designation of early cancer in BE by using a clock-face orientation. One hundred nineteen of 131 patients referred for endoscopic eradication therapy had a location designation for their advanced histology (91.9%). There were a total of 57 patients (47.9%) with HGD and 62 patients (52.1%) with ImCa. There was a significantly higher rate of early cancer (HGD or ImCa) in the right hemisphere (12 to 6 o'clock location) compared with the left hemisphere (84.9% vs 15.1%, P < .0001). The highest percentage of early cancer was found in the 12 to 3 o'clock quadrant (64.7%); 71.9% of HGD and 58.1% of ImCa lesions were located in the 12 to 3 o'clock quadrant. Retrospective design, single center. Early cancer associated with BE is far more commonly found in the right hemisphere of the esophagus (12 to 6 o'clock) with the highest rate in the 12 to 3 o'clock quadrant. These findings support enhanced scrutiny of the right hemisphere of the esophagus during surveillance and endoscopic treatment of patients with BE. Copyright © 2013 American Society for Gastrointestinal Endoscopy. Published by Mosby, Inc. All rights reserved.

  5. Solid State Research

    DTIC Science & Technology

    1975-04-17

    1-3. CO2 laser raster scan sensitivity profile of HgCdTe quadrantal array with two of the four elements connected to 50-ohm load. Fig. 1-4...Response of HgCdTe quadrantal array to CO2 laser beam scanned across center with (a) two opposite photodiodes connected, and (b) all four photodiodes...RESEARCH 1 A. Planar HgCdTe Quadrantal Arrays for Gigahertz Heterodyne Operation at 10.6 (im 1 B. Electrical Properties of Silicon Ion-Implanted

  6. Research on correction algorithm of laser positioning system based on four quadrant detector

    NASA Astrophysics Data System (ADS)

    Gao, Qingsong; Meng, Xiangyong; Qian, Weixian; Cai, Guixia

    2018-02-01

    This paper first introduces the basic principle of the four quadrant detector, and a set of laser positioning experiment system is built based on the four quadrant detector. Four quadrant laser positioning system in the actual application, not only exist interference of background light and detector dark current noise, and the influence of random noise, system stability, spot equivalent error can't be ignored, so it is very important to system calibration and correction. This paper analyzes the various factors of system positioning error, and then propose an algorithm for correcting the system error, the results of simulation and experiment show that the modified algorithm can improve the effect of system error on positioning and improve the positioning accuracy.

  7. Temperature field determination in slabs, circular plates and spheres with saw tooth heat generating sources

    NASA Astrophysics Data System (ADS)

    Diestra Cruz, Heberth Alexander

    The Green's functions integral technique is used to determine the conduction heat transfer temperature field in flat plates, circular plates, and solid spheres with saw tooth heat generating sources. In all cases the boundary temperature is specified (Dirichlet's condition) and the thermal conductivity is constant. The method of images is used to find the Green's function in infinite solids, semi-infinite solids, infinite quadrants, circular plates, and solid spheres. The saw tooth heat generation source has been modeled using Dirac delta function and Heaviside step function. The use of Green's functions allows obtain the temperature distribution in the form of an integral that avoids the convergence problems of infinite series. For the infinite solid and the sphere, the temperature distribution is three-dimensional and in the cases of semi-infinite solid, infinite quadrant and circular plate the distribution is two-dimensional. The method used in this work is superior to other methods because it obtains elegant analytical or quasi-analytical solutions to complex heat conduction problems with less computational effort and more accuracy than the use of fully numerical methods.

  8. Extent of resection in temporal lobectomy for epilepsy. II. Memory changes and neurologic complications.

    PubMed

    Katz, A; Awad, I A; Kong, A K; Chelune, G J; Naugle, R I; Wyllie, E; Beauchamp, G; Lüders, H

    1989-01-01

    We present correlations of extent of temporal lobectomy for intractable epilepsy with postoperative memory changes (20 cases) and abnormalities of visual field and neurologic examination (45 cases). Postoperative magnetic resonance imaging (MRI) in the coronal plane was used to quantify anteroposterior extent of resection of various quadrants of the temporal lobe, using a 20-compartment model of that structure. The Wechsler Memory Scale-Revised (WMS-R) was administered preoperatively and postoperatively. Postoperative decrease in percentage of retention of verbal material correlated with extent of medial resection of left temporal lobe, whereas decrease in percentage of retention of visual material correlated with extent of medial resection of right temporal lobe. These correlations approached but did not reach statistical significance. Extent of resection correlated significantly with the presence of visual field defect on perimetry testing but not with severity, denseness, or congruity of the defect. There was no correlation between postoperative dysphasia and extent of resection in any quadrant. Assessment of extent of resection after temporal lobectomy allows a rational interpretation of postoperative neurologic deficits in light of functional anatomy of the temporal lobe.

  9. Splenic infarction in a patient hereditary spherocytosis, protein C deficiency and acute infectious mononucleosis.

    PubMed

    Breuer, Christian; Janssen, Gisela; Laws, Hans-Jürgen; Schaper, Jörg; Mayatepek, Ertan; Schroten, Horst; Tenenbaum, Tobias

    2008-12-01

    Splenic infarction is a common cause of left upper quadrant pain and must be suspected in patients with hematologic or thromboembolic conditions and signs of localized or systemic inflammation. Although several mechanisms have been proposed for splenic infarction in patients with various hematologic disorders, hereditary spherocytosis (HS) is usually not associated with an increased risk for thromboembolic events. We report a 13-year-old male with HS who was referred to our hospital with a 4-day history of fever and left upper quadrant pain. Ultrasound scans and magnetic resonance imaging showed lesions suggestive of splenic infarction. Initially, antibiotic treatment was started because secondary infection was suspected. However, 1 week after admission the patient developed typical clinical signs of acute infectious mononucleosis. Further laboratory work up confirmed the diagnosis of acute Epstein-Barr virus infection and additionally revealed protein C deficiency. This association has not been reported previously and may have contributed to the development of splenic infarction. Since infectious mononucleosis is a common cause for clinical consultations in adolescence, physicians caring for children with hematologic disorders should be particularly aware of those possible complications.

  10. Splenic infarction as a rare complication of infectious mononucleosis due to Epstein-Barr virus infection in a patient with no significant comorbidity: case report and review of the literature.

    PubMed

    Gavriilaki, Eleni; Sabanis, Nikolaos; Paschou, Eleni; Grigoriadis, Savas; Mainou, Maria; Gaitanaki, Alexandra; Skargani-Koraka, Maria

    2013-11-01

    We report the case of a 17-y-old boy diagnosed with infectious mononucleosis due to Epstein-Barr virus infection who complained of left upper quadrant pain. A magnetic resonance imaging scan showed a splenic infarct in the enlarged spleen. Other causes of splenic infarction were excluded. Thus, infectious mononucleosis may cause splenic infarction in patients without other comorbidities.

  11. Tokyo, Yokohama and Tokoy Bay as seen from STS-58

    NASA Image and Video Library

    1993-10-30

    STS058-103-080 (18 Oct-1 Nov 1993) --- Japan's modern megalopolis is seen in this nadir view in great detail. More than 80 vessels can be seen at the anchorage's in Tokyo Bay. The gardens of the Emperor's Palace are seen in this circular area in the upper left quadrant. Even greater detail of this area was captured in the simultaneous color infrared image acquired during this space shuttle mission. (That photo number is STS058-110-085.)

  12. Object Recognition Using Range Images.

    DTIC Science & Technology

    1985-12-01

    and Reflectance Data to Find Planar Suface Regions," IEEE Transactions on Pattern Reco1iio n and Machine Intelligence , PAMI-l: 259-271 (July 1979...large number of data points. The dashed curve in the second through fourth qua- drants was drawn so as to parallel the curve in the first quadrant. One...find too much data . This lack of data has to do with the discri- mination ability of SDFs for objects of which the SDF’s are not composed. Thus for

  13. Three-Dimensional Anatomic Evaluation of the Anterior Cruciate Ligament for Planning Reconstruction

    PubMed Central

    Hoshino, Yuichi; Kim, Donghwi; Fu, Freddie H.

    2012-01-01

    Anatomic study related to the anterior cruciate ligament (ACL) reconstruction surgery has been developed in accordance with the progress of imaging technology. Advances in imaging techniques, especially the move from two-dimensional (2D) to three-dimensional (3D) image analysis, substantially contribute to anatomic understanding and its application to advanced ACL reconstruction surgery. This paper introduces previous research about image analysis of the ACL anatomy and its application to ACL reconstruction surgery. Crucial bony landmarks for the accurate placement of the ACL graft can be identified by 3D imaging technique. Additionally, 3D-CT analysis of the ACL insertion site anatomy provides better and more consistent evaluation than conventional “clock-face” reference and roentgenologic quadrant method. Since the human anatomy has a complex three-dimensional structure, further anatomic research using three-dimensional imaging analysis and its clinical application by navigation system or other technologies is warranted for the improvement of the ACL reconstruction. PMID:22567310

  14. Novel motor design for rotating anode x-ray tubes operating in the fringe field of a magnetic resonance imaging system

    PubMed Central

    Lillaney, Prasheel; Shin, Mihye; Hinshaw, Waldo; Bennett, N. Robert; Pelc, Norbert; Fahrig, Rebecca

    2013-01-01

    Purpose: Using hybrid x-ray/MR (XMR) systems for image guidance during interventional procedures could enhance the diagnosis and treatment of neurologic, oncologic, cardiovascular, and other disorders. The authors propose a close proximity hybrid system design in which a C-arm fluoroscopy unit is placed immediately adjacent to the solenoid magnet of a MR system with a minimum distance of 1.2 m between the x-ray and MR imaging fields of view. Existing rotating anode x-ray tube designs fail within MR fringe field environments because the magnetic fields alter the electron trajectories in the x-ray tube and act as a brake on the induction motor, reducing the rotation speed of the anode. In this study the authors propose a novel motor design that avoids the anode rotation speed reduction. Methods: The proposed design replaces the permanent magnet stator found in brushed dc motors with the radial component of the MR fringe field. The x-ray tube is oriented such that the radial component of the MR fringe field is orthogonal to the cathode-anode axis. Using a feedback position sensor and the support bearings as electrical slip rings, the authors use electrical commutation to eliminate the need for mechanical brushes and commutators. A vacuum compatible prototype of the proposed motor design was assembled, and its performance was evaluated at various operating conditions. The prototype consisted of a 3.1 in. diameter anode rated at 300 kHU with a ceramic rotor that was 5.6 in. in length and had a 2.9 in. diameter. The material chosen for all ceramic components was MACOR, a machineable glass ceramic developed by Corning Inc. The approximate weight of the entire assembly was 1750 g. The maximum rotation speed, angular acceleration, and acceleration time of the motor design were investigated, as well as the dependence of these parameters on rotor angular offset, magnetic field strength, and field orientation. The resonance properties of the authors’ assembly were also evaluated to determine its stability during acceleration, and a pulse width modulation algorithm was implemented to control the rotation speed of the motor. Results: At a magnetic flux density of 41 mT orthogonal to the axis of rotation (on the lower end of the expected flux density in the MR suite) the maximum speed of the motor was found to be 5150 revolutions per minute (rpm). The acceleration time necessary to reach 3000 rpm was found to be approximately 10 s at 59 mT. The resonance frequency of the assembly with the anode attached was 1310 rpm (21.8 Hz) which is far below the desired operating speeds. Pulse width modulation provides an effective method to control the speed of the motor with a resolution of 100 rpm. Conclusions: The proposed design can serve as a direct replacement to the conventional induction motor used in rotating anode x-ray tubes. It does not suffer from a reduced rotation speed when operating in a MR environment. The presence of chromic steel bearings in the prototype prevented testing at the higher field strengths, and future iterations of the design could eliminate this shortcoming. The prototype assembly demonstrates proof of concept of the authors’ design and overcomes one of the major obstacles for a MR compatible rotating anode x-ray tube. PMID:23387764

  15. Novel motor design for rotating anode x-ray tubes operating in the fringe field of a magnetic resonance imaging system.

    PubMed

    Lillaney, Prasheel; Shin, Mihye; Hinshaw, Waldo; Bennett, N Robert; Pelc, Norbert; Fahrig, Rebecca

    2013-02-01

    Using hybrid x-ray∕MR (XMR) systems for image guidance during interventional procedures could enhance the diagnosis and treatment of neurologic, oncologic, cardiovascular, and other disorders. The authors propose a close proximity hybrid system design in which a C-arm fluoroscopy unit is placed immediately adjacent to the solenoid magnet of a MR system with a minimum distance of 1.2 m between the x-ray and MR imaging fields of view. Existing rotating anode x-ray tube designs fail within MR fringe field environments because the magnetic fields alter the electron trajectories in the x-ray tube and act as a brake on the induction motor, reducing the rotation speed of the anode. In this study the authors propose a novel motor design that avoids the anode rotation speed reduction. The proposed design replaces the permanent magnet stator found in brushed dc motors with the radial component of the MR fringe field. The x-ray tube is oriented such that the radial component of the MR fringe field is orthogonal to the cathode-anode axis. Using a feedback position sensor and the support bearings as electrical slip rings, the authors use electrical commutation to eliminate the need for mechanical brushes and commutators. A vacuum compatible prototype of the proposed motor design was assembled, and its performance was evaluated at various operating conditions. The prototype consisted of a 3.1 in. diameter anode rated at 300 kHU with a ceramic rotor that was 5.6 in. in length and had a 2.9 in. diameter. The material chosen for all ceramic components was MACOR, a machineable glass ceramic developed by Corning Inc. The approximate weight of the entire assembly was 1750 g. The maximum rotation speed, angular acceleration, and acceleration time of the motor design were investigated, as well as the dependence of these parameters on rotor angular offset, magnetic field strength, and field orientation. The resonance properties of the authors' assembly were also evaluated to determine its stability during acceleration, and a pulse width modulation algorithm was implemented to control the rotation speed of the motor. At a magnetic flux density of 41 mT orthogonal to the axis of rotation (on the lower end of the expected flux density in the MR suite) the maximum speed of the motor was found to be 5150 revolutions per minute (rpm). The acceleration time necessary to reach 3000 rpm was found to be approximately 10 s at 59 mT. The resonance frequency of the assembly with the anode attached was 1310 rpm (21.8 Hz) which is far below the desired operating speeds. Pulse width modulation provides an effective method to control the speed of the motor with a resolution of 100 rpm. The proposed design can serve as a direct replacement to the conventional induction motor used in rotating anode x-ray tubes. It does not suffer from a reduced rotation speed when operating in a MR environment. The presence of chromic steel bearings in the prototype prevented testing at the higher field strengths, and future iterations of the design could eliminate this shortcoming. The prototype assembly demonstrates proof of concept of the authors' design and overcomes one of the major obstacles for a MR compatible rotating anode x-ray tube.

  16. Retina ganglion cell/inner plexiform layer and peripapillary nerve fiber layer thickness in patients with acromegaly.

    PubMed

    Şahin, Muhammed; Şahin, Alparslan; Kılınç, Faruk; Yüksel, Harun; Özkurt, Zeynep Gürsel; Türkcü, Fatih Mehmet; Pekkolay, Zafer; Soylu, Hikmet; Çaça, İhsan

    2017-06-01

    Increased secretion of growth hormone and insulin-like growth factor-1 in acromegaly has various effects on multiple organs. However, the ocular effects of acromegaly have yet to be investigated in detail. The aim of the present study was to compare retina ganglion cell/inner plexiform layer (GCIPL) and peripapillary nerve fiber layer thickness (pRNFL) between patients with acromegaly and healthy control subjects using spectral domain optical coherence tomography (SD-OCT). This cross-sectional, comparative study included 18 patients with acromegaly and 20 control subjects. All participants underwent SD-OCT to measure pRNFL (in the seven peripapillary areas), GCIPL (in the nine ETDRS areas), and central macular thickness (CMT). Visual field (VF) examinations were performed using a Humphrey field analyzer in acromegalic patients. Measurements were compared between patients with acromegaly and control subjects. A total of 33 eyes of 18 patients with acromegaly and 40 eyes of 20 control subjects met the inclusion criteria of the present study. The overall calculated average pRNFL thickness was significantly lower in patients with acromegaly than in control subjects (P = 0.01), with pRNFL thickness significantly lower in the temporal superior and temporal inferior quadrants. Contrary to our expectations, pRNFL thickness in the nasal quadrant was similar between acromegalic and control subjects. The mean overall pRNFL thickness and superonasal, nasal, inferonasal, and inferotemporal quadrant pRNFL thicknesses were found to correlate with the mean deviation (MD) according to Spearman's correlation. However, other quadrants were not correlated with VF sensitivity. No significant difference in CMT values was observed (P = 0.6). GCIPL thickness was significantly lower in all quadrants of the inner and outer macula, except for central and inferior outer quadrants, in the acromegaly group than that in the control group (P < 0.05). GCIPL thicknesses of the inferior inner and outer macula quadrants were found to correlate with MD, whereas no correlation was observed between other quadrants and VF sensitivity. We demonstrated that GCIPL thickness decreased in patients with acromegaly compared with that in control subjects. However, the nasal quadrant pRNFL thickness was similar in acromegaly, in contrast to our expectations. SD-OCT may have utility in the assessment of the effects of acromegaly on retinal structures.

  17. Generalized spin filtering and an improved derivative-sign binary image method for the extraction of fringe skeletons

    NASA Astrophysics Data System (ADS)

    Yu, Qifeng; Liu, Xiaolin; Sun, Xiangyi

    1998-07-01

    Generalized spin filters, including several directional filters such as the directional median filter and the directional binary filter, are proposed for removal of the noise of fringe patterns and the extraction of fringe skeletons with the help of fringe-orientation maps (FOM s). The generalized spin filters can filter off noise on fringe patterns and binary fringe patterns efficiently, without distortion of fringe features. A quadrantal angle filter is developed to filter off the FOM. With these new filters, the derivative-sign binary image (DSBI) method for extraction of fringe skeletons is improved considerably. The improved DSBI method can extract high-density skeletons as well as common density skeletons.

  18. Experiments in encoding multilevel images as quadtrees

    NASA Technical Reports Server (NTRS)

    Lansing, Donald L.

    1987-01-01

    Image storage requirements for several encoding methods are investigated and the use of quadtrees with multigray level or multicolor images are explored. The results of encoding a variety of images having up to 256 gray levels using three schemes (full raster, runlength and quadtree) are presented. Although there is considerable literature on the use of quadtrees to store and manipulate binary images, their application to multilevel images is relatively undeveloped. The potential advantage of quadtree encoding is that an entire area with a uniform gray level may be encoded as a unit. A pointerless quadtree encoding scheme is described. Data are presented on the size of the quadtree required to encode selected images and on the relative storage requirements of the three encoding schemes. A segmentation scheme based on the statistical variation of gray levels within a quadtree quadrant is described. This parametric scheme may be used to control the storage required by an encoded image and to preprocess a scene for feature identification. Several sets of black and white and pseudocolor images obtained by varying the segmentation parameter are shown.

  19. Skin Dosimetry in Breast Teletherapy on a Phantom Anthropomorphic and Anthropometric Phantom

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Batista Nogueira, Luciana; Lemos Silva, Hugo Leonardo; Donato da Silva, Sabrina

    This paper addresses the breast teletherapy dosimetry. The goal is to evaluate and compare absorbed doses in equivalent skin tissue, TE-skin, of an anthropomorphic and anthropometric breast phantom submitted to breast radiotherapy. The methodology involved the reproduction of a set of tomographic images of the phantom; the elaboration of conformational radiotherapy planning in the SOMAVISION and CadPlan (TPS) software; and the synthetic breast irradiation by parallel opposed fields in 3D conformal teletherapy at 6 MV linear accelerator Clinac-2100 C from VARIAN with prescribed dose (PD) of 180 cGy to the target volume (PTV), referent to the glandular tissue. Radiochromic filmsmore » EBT2 were selected as dosimeters. Two independent calibration processes of films with solid water Gammex 457 plates and water filled box were produced. Curves of optical density (OD) versus absorbed dose were produced. Dosimeters were positioned in the external region of the breast phantom in contact with TE-skin, area of 4.0 cm{sup 2} each. The irradiation process was prepared in duplicate to check the reproducibility of the technique. The radiochromic films were scanned and their response in RGB (Red, Green, Blue) analyzed by the ImageJ software. The optical density was obtained and converted to dose based on the calibration curves. Thus, the spatial dose distribution in the skin was reproduced. The absorbed doses measured on the radiochromic films in TE-skin showed values between upper and lower quadrants at 9 o'clock in the range of 54% of PD, between the upper and lower quadrants 3 o'clock in the range of 72% and 6 o'clock at the lower quadrant in the range of 68 % of PD. The values are ±64% (p <0.05) according to the TPS. It is concluded that the depth dose measured in solid water plates or water box reproduce equivalent dose values for both calibration processes of the radiochromic films. It was observed that the skin received doses ranging from 50% to 78% of the prescribed dose after two parallel opposed irradiation fields. (authors)« less

  20. [Clinical significance of four quadrant localization in the diagnosis and treatment of metastatic carcinoma of the neck with unknown primary].

    PubMed

    Gao, Y Y; Chen, X H

    2017-06-05

    Objective: The aim of this study is to investigate the clinical significance of four quadrant localization in the diagnosis and treatment of unknown primary cervical metastases. Method: The clinical data with unknown primary cervical metastases, were analyzed retrospectively. All the patients have not been found the original site in the initial treatment. There are four quadrants in the neck, the neck line as the longitudinal axis, and edge of cricoid cartilage as the horizontal axis. When cervical metastasis occurred in the left and right upper quadrant, the primary tumor site and radiotherapy from the skull base to the root of the neck; when appear in left and right lower quadrant, the primary investigation site and radiotherapy from neck to thoracic mediastinum, left lower abdomen also includes following primary search. At the same time, bilateral cervical metastasis cancers, focusing on the central line near the primary focus. Specific treatment strategies include ipsilateral total neck dissection and radical radiotherapy of the above radiotherapy site. Result: Left upper neck in 4 cases, right upper neck in 5 cases, left lower neck in 7 cases, lower right neck in 8 cases and mixed area in 6 cases. Only 10 of 30 patients (33.3%) with primary sites were found in the follow up period. In accordance with the four quadrant localization, the median time was 6 months. Conclusion: Four quadrant localization to locate the primary site is accurate, and individualized comprehensive treatment is the key to improve the curative effect. Copyright© by the Editorial Department of Journal of Clinical Otorhinolaryngology Head and Neck Surgery.

  1. Poor Prognosis of Lower Inner Quadrant in Lymph Node-negative Breast Cancer Patients Who Received No Chemotherapy: A Study Based on Nationwide Korean Breast Cancer Registry Database.

    PubMed

    Hwang, Ki-Tae; Kim, Jongjin; Kim, Eun-Kyu; Jung, Sung Hoo; Sohn, Guiyun; Kim, Seung Il; Jeong, Joon; Lee, Hyouk Jin; Park, Jin Hyun; Oh, Sohee

    2017-07-01

    We aimed to investigate the prognostic influence of primary tumor site on the survival of patients with breast cancer. Data of 63,388 patients with primary breast cancer from the Korean Breast Cancer Registry were analyzed. Primary tumor sites were classified into 5 groups: upper outer quadrant, lower outer quadrant, upper inner quadrant, lower inner quadrant (LIQ), and central portion. We analyzed overall survival (OS) and breast cancer-specific survival (BCSS) according to primary tumor site. Central portion and LIQ showed lower survival rates regarding both OS and BCSS compared with the other 3 quadrants (all P < .05) and hazard ratios were 1.267 (95% CI, 1.180-1.360, P < .001) and 1.215 (95% CI, 1.097-1.345, P < .001), respectively. Although central portion showed more unfavorable clinicopathologic features, LIQ showed more favorable features than the other 3 quadrants. Primary tumor site was a significant factor in univariate and multivariate analyses for OS and BCSS (all P < .001). For lymph node-negative patients, LIQ showed a worse OS than the other primary tumor sites in the subgroup with no chemotherapy (P < .001), but that effect disappeared in the subgroup with chemotherapy (P = .058). LIQ showed a worse prognosis despite having more favorable clinicopathologic features than other tumor locations and it was more prominent for lymph node-negative patients who received no chemotherapy. The hypothesis of possible hidden internal mammary node metastasis could be suggested to play a key role in LIQ lesions. Copyright © 2017 Elsevier Inc. All rights reserved.

  2. Characterizing the Propagation of Uterine Electrophysiological Signals Recorded with a Multi-Sensor Abdominal Array in Term Pregnancies.

    PubMed

    Escalona-Vargas, Diana; Govindan, Rathinaswamy B; Furdea, Adrian; Murphy, Pam; Lowery, Curtis L; Eswaran, Hari

    2015-01-01

    The objective of this study was to quantify the number of segments that have contractile activity and determine the propagation speed from uterine electrophysiological signals recorded over the abdomen. The uterine magnetomyographic (MMG) signals were recorded with a 151 channel SARA (SQUID Array for Reproductive Assessment) system from 36 pregnant women between 37 and 40 weeks of gestational age. The MMG signals were scored and segments were classified based on presence of uterine contractile burst activity. The sensor space was then split into four quadrants and in each quadrant signal strength at each sample was calculated using center-of-gravity (COG). To this end, the cross-correlation analysis of the COG was performed to calculate the delay between pairwise combinations of quadrants. The relationship in propagation across the quadrants was quantified and propagation speeds were calculated from the delays. MMG recordings were successfully processed from 25 subjects and the average values of propagation speeds ranged from 1.3-9.5 cm/s, which was within the physiological range. The propagation was observed between both vertical and horizontal quadrants confirming multidirectional propagation. After the multiple pairwise test (99% CI), significant differences in speeds can be observed between certain vertical or horizontal combinations and the crossed pair combinations. The number of segments containing contractile activity in any given quadrant pair with a detectable delay was significantly higher in the lower abdominal pairwise combination as compared to all others. The quadrant-based approach using MMG signals provided us with high spatial-temporal information of the uterine contractile activity and will help us in the future to optimize abdominal electromyographic (EMG) recordings that are practical in a clinical setting.

  3. Characterizing the Propagation of Uterine Electrophysiological Signals Recorded with a Multi-Sensor Abdominal Array in Term Pregnancies

    PubMed Central

    Escalona-Vargas, Diana; Govindan, Rathinaswamy B.; Furdea, Adrian; Murphy, Pam; Lowery, Curtis L.; Eswaran, Hari

    2015-01-01

    The objective of this study was to quantify the number of segments that have contractile activity and determine the propagation speed from uterine electrophysiological signals recorded over the abdomen. The uterine magnetomyographic (MMG) signals were recorded with a 151 channel SARA (SQUID Array for Reproductive Assessment) system from 36 pregnant women between 37 and 40 weeks of gestational age. The MMG signals were scored and segments were classified based on presence of uterine contractile burst activity. The sensor space was then split into four quadrants and in each quadrant signal strength at each sample was calculated using center-of-gravity (COG). To this end, the cross-correlation analysis of the COG was performed to calculate the delay between pairwise combinations of quadrants. The relationship in propagation across the quadrants was quantified and propagation speeds were calculated from the delays. MMG recordings were successfully processed from 25 subjects and the average values of propagation speeds ranged from 1.3–9.5 cm/s, which was within the physiological range. The propagation was observed between both vertical and horizontal quadrants confirming multidirectional propagation. After the multiple pairwise test (99% CI), significant differences in speeds can be observed between certain vertical or horizontal combinations and the crossed pair combinations. The number of segments containing contractile activity in any given quadrant pair with a detectable delay was significantly higher in the lower abdominal pairwise combination as compared to all others. The quadrant-based approach using MMG signals provided us with high spatial-temporal information of the uterine contractile activity and will help us in the future to optimize abdominal electromyographic (EMG) recordings that are practical in a clinical setting. PMID:26505624

  4. A new color vision test to differentiate congenital and acquired color vision defects.

    PubMed

    Shin, Young Joo; Park, Kyu Hyung; Hwang, Jeong-Min; Wee, Won Ryang; Lee, Jin Hak

    2007-07-01

    To investigate the efficacy of a novel computer-controlled color test for the differentiation of congenital and acquired color vision deficiency. Observational cross-sectional study. Thirty-one patients with congenital color vision deficiency and 134 patients with acquired color vision deficiency with a Snellen visual acuity better than 20/30 underwent an ophthalmologic examination including the Ishihara color test, Hardy-Rand-Rittler test, Nagel anomaloscopy, and the Seohan computerized hue test between June, 2003, and January, 2004. To investigate the type of color vision defect, a graph of the Seohan computerized hue test was divided into 4 quadrants and error scores in each quadrant were summated. The ratio between the sums of error scores of quadrants I and III (Q1+Q3) and those of quadrants II and IV (Q2+Q4) was calculated. Error scores and ratio in quadrant analysis of the Seohan computerized hue test. The Seohan computerized hue test showed that the sum of Q2+Q4 was significantly higher than the sum of Q1+Q3 in congenital color vision deficiency (P<0.01, paired t test) and that the sum of Q2+Q4 was significantly lower than the sum of Q1+Q3 in acquired color vision deficiency (P<0.01, paired t test). In terms of discriminating congenital and acquired color vision deficiency, the ratio in quadrant analysis had 93.3% sensitivity and 98.5% specificity with a reference value of 1.5 by the Seohan computerized hue test (95% confidence interval). The quadrant analysis and ratio of (Q2+Q4)/(Q1+Q3) using the Seohan computerized hue test effectively differentiated congenital and acquired color vision deficiency.

  5. Development of Point of Care Testing Device for Neurovascular Coupling From Simultaneous Recording of EEG and NIRS During Anodal Transcranial Direct Current Stimulation

    PubMed Central

    Jindal, Utkarsh; Sood, Mehak; Dutta, Anirban; Chowdhury, Shubhajit Roy

    2015-01-01

    This paper presents a point of care testing device for neurovascular coupling (NVC) from simultaneous recording of electroencephalogram (EEG) and near infrared spectroscopy (NIRS) during anodal transcranial direct current stimulation (tDCS). Here, anodal tDCS modulated cortical neural activity leading to hemodynamic response can be used to identify the impaired cerebral microvessels functionality. The impairments in the cerebral microvessels functionality may lead to impairments in the cerebrovascular reactivity (CVR), where severely reduced CVR predicts the chances of transient ischemic attack and ipsilateral stroke. The neural and hemodynamic responses to anodal tDCS were studied through joint imaging with EEG and NIRS, where NIRS provided optical measurement of changes in tissue oxy-(\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{upgreek} \\usepackage{mathrsfs} \\setlength{\\oddsidemargin}{-69pt} \\begin{document} }{}$HbO2)$ \\end{document} and deoxy-(\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{upgreek} \\usepackage{mathrsfs} \\setlength{\\oddsidemargin}{-69pt} \\begin{document} }{}$Hb$ \\end{document}) hemoglobin concentration and EEG captured alterations in the underlying neuronal current generators. Then, a cross-correlation method for the assessment of NVC underlying the site of anodal tDCS is presented. The feasibility studies on healthy subjects and stroke survivors showed detectable changes in the EEG and the NIRS responses to a 0.526 A/\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{upgreek} \\usepackage{mathrsfs} \\setlength{\\oddsidemargin}{-69pt} \\begin{document} }{}$\\mathrm{m}^{2}$ \\end{document} of anodal tDCS. The NIRS system was bench tested on 15 healthy subjects that showed a statistically significant (p < 0.01) difference in the signal-to-noise ratio (SNR) between the ON- and OFF-states of anodal tDCS where the mean SNR of the NIRS device was found to be 42.33 ± 1.33 dB in the ON-state and 40.67 ± 1.23 dB in the OFF-state. Moreover, the clinical study conducted on 14 stroke survivors revealed that the lesioned hemisphere with impaired circulation showed significantly (p < 0.01) less change in \\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{upgreek} \\usepackage{mathrsfs} \\setlength{\\oddsidemargin}{-69pt} \\begin{document} }{}$HbO2$ \\end{document} than the nonlesioned side in response to anodal tDCS. The EEG study on healthy subjects showed a statistically significant (p < 0.05) decrease around individual alpha frequency in the alpha band (8−13 Hz) following anodal tDCS. Moreover, the joint EEG-NIRS imaging on 4 stroke survivors showed an immediate increase in the theta band (4−8 Hz) EEG activity after the start of anodal tDCS at the nonlesioned hemisphere. Furthermore, cross-correlation function revealed a significant (95% confidence interval) negative cross correlation only at the nonlesioned hemisphere during anodal tDCS, where the log-transformed mean-power of EEG within 0.5−11.25 Hz lagged \\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{upgreek} \\usepackage{mathrsfs} \\setlength{\\oddsidemargin}{-69pt} \\begin{document} }{}$HbO2$ \\end{document} response in one of the stroke survivors with white matter lesions. Therefore, it was concluded that the anodal tDCS can perturb the local neural and the vascular activity (via NVC) which can be used for assessing regional NVC functionality where confirmatory clinical studies are required. PMID:27170897

  6. Thermography Examination of Abdominal Area Skin Temperatures in Individuals With and Without Focal-Onset Epilepsy.

    PubMed

    King, Hollis H; Cayce, Charles Thomas; Herrin, Jeph

    Early osteopathic theory and practice, and the work of the medical intuitive Edgar Cayce suggested that the abdominal areas of individuals with epilepsy would manifest "cold spots." The etiology for this phenomenon was thought to be abdominal adhesions caused by inflammation and viscero-somatic reflexes caused by adhesions or injury to visceral or musculoskeletal system structures. Indeed, until that advent of electroencephalography in the 1930s, medical practice regarding epilepsy focused on abdominal neural and visceral structures. Following two hypotheses were formulated to evaluate any abdominal temperature phenomena: (1) an abdominal quadrant division analysis would find one or more quadrants "colder" in the focal-onset epilepsy group (ICD9-CM 345.4 and 345.5) compared to controls. (2) Total abdominal areas of individuals with focal-onset epilepsy wound be colder than a control group. Overall, 50 patients with the diagnosis of focal-onset epilepsy were recruited from the office of the Epilepsy Foundation of Florida and 50 control subjects with no history of epilepsy were recruited through advertising to the public. Under controlled room conditions all subjects had infrared thermographic images made and recorded by Med-Hot Model MH-731 FLIR equipment. There were no significant demographic difference between experimental patients and control subjects, though the control group tended to be younger and more often male; however, these were controlled for in all analyses. In the quadrant analysis, there were significant differences in that more epileptic patients had colder left upper abdominal quadrant temperatures than the control group (66.8% versus 44.9%; P = .030). In the total abdominal analysis, however, there were no significant differences. The results support the hypothesis that individuals with focal-onset epilepsy have colder abdominal areas. If substantiated in further research, present study results will require further examination of the mechanisms of action for epilepsy, and suggest the need for re-examination of older formulations of abdominal epilepsy, including the place of abdominal injury, inflammation, and adhesions in epileptic pathology. The concept of somato-visceral and viscero-somatic neurological interactions is one of the possible mechanisms underlying the "cold spot" findings and warrants further consideration. Copyright © 2017 Elsevier Inc. All rights reserved.

  7. The IRAS Minor Planet Survey

    DTIC Science & Technology

    1992-12-01

    ecliptic longitude changed from -2100 to -2600 over the course of the IRAS mission. Thus, in these plots it would be located in the lower left quadrant ...degrees ecliptic longitude is towards the top of this plot. During the 1983 IRAS mission, Jupiter was in the lower left quadrant near an ecliptic...Most hot stars and cold background sources are outside the range of this color window (cf., lower right quadrant of Fig. 15). The 12 pm to 25 prm

  8. Ti/IrO2/SnO2 anode for electrochemical degradation of chlorpyrifos in water: optimization and degradation performances

    NASA Astrophysics Data System (ADS)

    Pathiraja, G. C.; Wijesingha, M. S.; Nanayakkara, N.

    2017-05-01

    Chlorpyrifos, a widely used organophosphate pesticide which can be found in surface water bodies, is harmful for human body. Thus, treating water contaminated with chlorpyrifos is important. In our previous studies, novel Ti/IrO2-SnO2 anode was successfully developed for electrochemical degradation of chlorpyrifos in chloride free water. In this study, optimization of previously developed Ti/IrO2-SnO2 anode for mineralization of chlorpyrifos was successfully performed through response surface methodology. During the optimization study, two-level factorial design was used to determine the optimal coating solutions concentration for developing the Ti/IrO2-SnO2 anode. Cyclic voltammetry and open circuit potential were performed to investigate the electrochemically active surface area and stability of these anodes. The response surface and contour plots show that 0.3 M of [Ir] and 7.5 mM of [Sn] coated electrode has both highest anodic charge and stability. Scanning Electron Microscopic (SEM) images show the evidence of having both compact and porous regions in the surface of the thin film, resulting larger surface area. Within 6 h, the best result for mineralization (55.56%) of chlorpyrifos was obtained with 0.3 M of [Ir] and 7.5 mM of [Sn] coated anode using Total organic Carbon (TOC) analyzer. Therefore, the optimum coating concentration was found as 0.3 M of [Ir] and 7.5 mM of [Sn]. It would require an energy consumption of 6 kWhm-3.

  9. Clinical presentation and manual therapy for upper quadrant musculoskeletal conditions

    PubMed Central

    Isabel de-la-Llave-Rincón, Ana; Puentedura, Emilio J; Fernández-de-las-Peñas, César

    2011-01-01

    In recent years, increased knowledge of the pathogenesis of upper quadrant pain syndromes has translated to better management strategies. Recent studies have demonstrated evidence of peripheral and central sensitization mechanisms in different local pain syndromes of the upper quadrant such as idiopathic neck pain, lateral epicondylalgia, whiplash-associated disorders, shoulder impingement, and carpal tunnel syndrome. Therefore, a treatment-based classification approach where subjects receive matched interventions has been developed and, it has been found that these patients experience better outcomes than those receiving non-matched interventions. There is evidence suggesting that the cervical and thoracic spine is involved in upper quadrant pain. Spinal manipulation has been found to be effective for patients with elbow pain, neck pain, or cervicobrachial pain. Additionally, it is known that spinal manipulative therapy exerts neurophysiological effects that can activate pain modulation mechanisms. This paper exposes some manual therapies for upper quadrant pain syndromes, based on a nociceptive pain rationale for modulating central nervous system including trigger point therapy, dry needling, mobilization or manipulation, and cognitive pain approaches. PMID:23115473

  10. Comparison of EyeCam and anterior segment optical coherence tomography in detecting angle closure.

    PubMed

    Baskaran, Mani; Aung, Tin; Friedman, David S; Tun, Tin A; Perera, Shamira A

    2012-12-01

    To compare the diagnostic performance of EyeCam (Clarity Medical Systems, Pleasanton, CA, USA) and anterior segment optical coherence tomography (ASOCT, Visante; Carl Zeiss Meditec, Dublin, CA, USA) in detecting angle closure, using gonioscopy as the reference standard. Ninety-eight phakic patients, recruited from a glaucoma clinic, underwent gonioscopy by a single examiner, and EyeCam and ASOCT imaging by another examiner. Another observer, masked to gonioscopy findings, graded EyeCam and ASOCT images. For both gonioscopy and EyeCam, a closed angle in a particular quadrant was defined if the posterior trabecular meshwork was not visible. For ASOCT, angle closure was defined by any contact between the iris and angle anterior to the scleral spur. An eye was diagnosed as having angle closure if ≥2 quadrants were closed. Agreement and area under the receiver operating characteristic curves (AUC) were evaluated. The majority of subjects were Chinese (69/98, 70.4%) with a mean age of 60.6 years. Angle closure was diagnosed in 39/98 (39.8%) eyes with gonioscopy, 40/98 (40.8%) with EyeCam and 56/97 (57.7%) with ASOCT. The agreement (kappa statistic) for angle closure diagnosis for gonioscopy versus EyeCam was 0.89; gonioscopy versus ASOCT and EyeCam versus ASOCT were both 0.56. The AUC for detecting eyes with gonioscopic angle closure with EyeCam was 0.978 (95% CI: 0.93-1.0) and 0.847 (95% CI: 0.76-0.92, p < 0.01) for ASOCT. The diagnostic performance of EyeCam was better than ASOCT in detecting angle closure when gonioscopic grading was used as the reference standard. The agreement between the two imaging modalities was moderate. © 2012 The Authors. Acta Ophthalmologica © 2012 Acta Ophthalmologica Scandinavica Foundation.

  11. Tele-ultrasound and paramedics: real-time remote physician guidance of the Focused Assessment With Sonography for Trauma examination.

    PubMed

    Boniface, Keith S; Shokoohi, Hamid; Smith, E Reed; Scantlebury, Kari

    2011-06-01

    The aim of this study was to examine the capability of ultrasound-naïve paramedics to obtain interpretable Focused Assessment With Sonography for Trauma (FAST) images under the remote direction of emergency physicians (EPs). Paramedics without experience using ultrasound participated in a 20-minute lecture covering orientation to the ultrasound machine and the FAST examination. The paramedics subsequently performed FAST examinations on a model patient, whereas the EP remained in another room, out of visual contact. The EP communicated with the paramedic via radio, viewing video from the ultrasound machine on a monitor and directing the probe movements to obtain the views of the FAST examination. We examined the success rate, time to complete the examinations, and adequacy of images from the paramedics' first FAST examination. Fifty-one paramedics performed their first FAST examinations and were able to successfully complete 100% of the views of the FAST. The median time from probe placement to examination completion was 262 seconds (interquartile range, 206-343 seconds). The median time to complete right upper quadrant (RUQ) versus left upper quadrant (LUQ) views was 39 and 50 seconds, respectively. The time to complete the LUQ scan took significantly longer than the RUQ (P < .01). Paramedics completed cardiac and pelvic view in a median time of 42 and 25 seconds, respectively. The study demonstrated that paramedics with no prior ultrasound experience could obtain FAST images under remote guidance from experienced EPs in less than 5 minutes. Given rapidly evolving data transmission technology, this has applicability in battlefield, remote, and rural prehospital settings. Copyright © 2011 Elsevier Inc. All rights reserved.

  12. Breakthrough in 4π ion emission mechanism understanding in plasma focus devices

    PubMed Central

    Sohrabi, Mehdi; Zarinshad, Arefe; Habibi, Morteza

    2016-01-01

    Ion emission angular distribution mechanisms in plasma focus devices (PFD) have not yet been well developed and understood being due to the lack of an efficient wide-angle ion distribution image detection system to characterize a PFD space in detail. Present belief is that the acceleration of ions points from “anode top” upwards in forward direction within a small solid angle. A breakthrough is reported in this study, by mega-size position-sensitive polycarbonate ion image detection systems invented, on discovery of 4π ion emission from the “anode top” in a PFD space after plasma pinch instability and radial run-away of ions from the “anode cathodes array” during axial acceleration of plasma sheaths before the radial phase. These two ion emission source mechanisms behave respectively as a “Point Ion Source” and a “Line Ion Source” forming “Ion Cathode Shadows” on mega-size detectors. We believe that the inventions and discoveries made here will open new horizons for advanced ion emission studies towards better mechanisms understanding and in particular will promote efficient applications of PFDs in medicine, science and technology. PMID:27941832

  13. Vertical structure of aeolian turbulence in a boundary layer with sand transport

    NASA Astrophysics Data System (ADS)

    Lee, Zoe S.; Baas, Andreas C. W.

    2016-04-01

    Recently we have found that Reynolds shear stress shows a significant variability with measurement height (Lee and Baas, 2016), and so an alternative parameter for boundary layer turbulence may help to explain the relationship between wind forcing and sediment transport. We present data that were collected during a field study of boundary layer turbulence conducted on a North Atlantic beach. High-frequency (50 Hz) 3D wind velocity measurements were collected using ultrasonic anemometry at thirteen different measurement heights in a tight vertical array between 0.11 and 1.62 metres above the surface. Thanks to the high density installation of sensors a detailed analysis of the boundary layer flow can be conducted using methods more typically used in studies where data is only available from one or just a few measurement heights. We use quadrant analysis to explore the vertical structure of turbulence and track the changes in quadrant signatures with measurement elevation and over time. Results of quadrant analysis, at the 'raw' 50 Hz timescale, demonstrates the tendency for event clustering across all four quadrants, which implies that at-a-point quadrant events are part of larger-scale turbulent structures. Using an HSV colour model, applied to the quadrant analysis data and plotted in series, we create colour maps of turbulence, which can provide a clear visualisation of the clustering of event activity at each height and illustrate the shape of the larger coherent flow structures that are present within the boundary layer. By including a saturation component to the colour model, the most significant stress producing sections of the data are emphasised. This results in a 'banded' colour map, which relates to clustering of quadrant I (Outward Interaction) and quadrant IV (Sweep) activity, separate from clustering of quadrant II (Burst) and quadrant III (Inward Interaction). Both 'sweep-type' and 'burst-type' sequences are shown to have a diagonal structure originating from the top of the boundary layer, indicating a downwards direction of eddy motion. While directionality of turbulence cannot be definitively determined, our results indicate that the top-down turbulence model is a suitable explanation, further supported by the presence of 'incomplete' eddies which originate at higher elevations but fail to extend to the surface. This provides the first evidence in support of a top down turbulence model as observed in aeolian geomorphology, and we present preliminary findings on its relationship to sand transport activity. Lee, Z.S., Baas, A.C.W. (2016) Variable and conflicting shear stress estimates inside a boundary layer with sediment transport. Earth Surface Processes and Landforms; DOI: 10.1002/esp.3829

  14. Turbulent Reynolds stress and quadrant event activity in wind flow over a coastal foredune

    NASA Astrophysics Data System (ADS)

    Chapman, Connie A.; Walker, Ian J.; Hesp, Patrick A.; Bauer, Bernard O.; Davidson-Arnott, Robin G. D.

    2012-05-01

    Recent research on quasi-instantaneous turbulent kinematic Reynolds stresses (RS, - u'w') and decomposed quadrant event activity (e.g., ejections and sweeps) over dunes in fluvial settings and in wind tunnels has shown that turbulent stresses at the toe of a dune often exceed time-averaged, streamwise shear stress (ρ u * 2) estimates. It is believed that semi-coherent turbulent structures are conveyed toward the bed along concave streamlines in this region and that impact of these structures cause fluctuations in local surface stresses that assist in grain entrainment. This has been hypothesized to explain how sand is supplied to the windward slope through a region of flow stagnation. Toward the crest, surface stress increases and becomes dominated by streamwise accelerations resulting from streamline compression and convexity that suppress vertical motions. High-frequency (32 Hz) measurements of turbulent wind flow from 3-D ultrasonic anemometers are analyzed for oblique onshore flow over a vegetated coastal foredune in Prince Edward Island, Canada. Reynolds stress and quadrant activity distributions varied with height (0.60 m and 1.66 m) and location over the dune. In general, quadrant 2 ejection (u' < 0, w' > 0) and quadrant 4 sweep activity (u' > 0, w' < 0) dominated momentum transfer and RS generation over quadrant 1 outward interaction (u' > 0, w' > 0) and quadrant 3 inward interaction (u' < 0, w' < 0) activity. On the lower stoss slope, significant ejection and sweep event activity was most frequent (85 to 92%, ejections plus sweeps), whereas, at the upper crest, significant ejection and sweep activity became less frequent while significant outward and inward interactions increased in frequency (25 to 36%). An 'exuberance effect' (i.e., changing shape of quadrant frequency distribution skewed toward ejection and sweep activity) is observed whereby streamline compression and convexity effects inhibit vertical fluctuations in flow and, thus, reduce the frequency of ejections and sweep activity toward the crest. In separated flow in the lee of the crest, quadrant distributions were more symmetrical as a result of more mixed, multi-directional flow. These trends in turbulent event distributions and Reynolds stress have implications for sediment transport dynamics across the dune and may help to explain sand transport potential and dune maintenance. For example, areas with a high frequency of ejection and sweep activity may have higher rates of sediment entrainment and transport, whereas areas with lower ejection and sweep activity and an increase in outward and inward interactions, which contribute negatively to Reynolds stress generation, may experience a greater potential for deposition. Further research on associations between quadrant event activity and coincident sand transport is required to confirm this hypothesis and the resultant significance of the flow exuberance effect in aeolian dune morphodynamics.

  15. Two-dimensional ultraviolet imagery with a microchannel-plate/resistive-anode detector

    NASA Technical Reports Server (NTRS)

    Opal, C. B.; Feldman, P. D.; Weaver, H. A.; Mcclintock, J. A.

    1979-01-01

    An imaging ultraviolet detector has been designed for use with a precision pointed telescope flown on a sounding rocket. Resolution of better than 80 microns over a field of 5 mm has been achieved. The ultraviolet image is converted to electrons at the front surface of a CsI coated chevron microchannel-plate electron multiplier. For each photoelectron, the multiplier produces a burst of about 3,000,000 electrons, which impinges on a tellurium-coated resistive anode with four evaporated hyperbolic readout electrodes. The sizes of the four resulting output pulses are digitized to 10 bit accuracy and telemetered to the ground, where they are divided in pairs to give the x and y coordinates of the photoelectron event. The coordinates are used to generate a picture in real time, and are recorded for computer processing later. The detector was successfully flown in December 1978. Good images of Jupiter and Capella in hydrogen Lyman alpha emission were obtained.

  16. Direct Synthesis of Carbon Nanotube Field Emitters on Metal Substrate for Open-Type X-ray Source in Medical Imaging.

    PubMed

    Gupta, Amar Prasad; Park, Sangjun; Yeo, Seung Jun; Jung, Jaeik; Cho, Chonggil; Paik, Sang Hyun; Park, Hunkuk; Cho, Young Chul; Kim, Seung Hoon; Shin, Ji Hoon; Ahn, Jeung Sun; Ryu, Jehwang

    2017-07-29

    We report the design, fabrication and characterization of a carbon nanotube enabled open-type X-ray system for medical imaging. We directly grew the carbon nanotubes used as electron emitter for electron gun on a non-polished raw metallic rectangular-rounded substrate with an area of 0.1377 cm² through a plasma enhanced chemical vapor deposition system. The stable field emission properties with triode electrodes after electrical aging treatment showed an anode emission current of 0.63 mA at a gate field of 7.51 V/μm. The 4.5-inch cubic shape open type X-ray system was developed consisting of an X-ray aperture, a vacuum part, an anode high voltage part, and a field emission electron gun including three electrodes with focusing, gate and cathode electrodes. Using this system, we obtained high-resolution X-ray images accelerated at 42-70 kV voltage by digital switching control between emitter and ground electrode.

  17. Direct Synthesis of Carbon Nanotube Field Emitters on Metal Substrate for Open-Type X-ray Source in Medical Imaging

    PubMed Central

    Gupta, Amar Prasad; Park, Sangjun; Yeo, Seung Jun; Jung, Jaeik; Cho, Chonggil; Paik, Sang Hyun; Park, Hunkuk; Cho, Young Chul; Kim, Seung Hoon; Shin, Ji Hoon; Ahn, Jeung Sun; Ryu, Jehwang

    2017-01-01

    We report the design, fabrication and characterization of a carbon nanotube enabled open-type X-ray system for medical imaging. We directly grew the carbon nanotubes used as electron emitter for electron gun on a non-polished raw metallic rectangular-rounded substrate with an area of 0.1377 cm2 through a plasma enhanced chemical vapor deposition system. The stable field emission properties with triode electrodes after electrical aging treatment showed an anode emission current of 0.63 mA at a gate field of 7.51 V/μm. The 4.5-inch cubic shape open type X-ray system was developed consisting of an X-ray aperture, a vacuum part, an anode high voltage part, and a field emission electron gun including three electrodes with focusing, gate and cathode electrodes. Using this system, we obtained high-resolution X-ray images accelerated at 42–70 kV voltage by digital switching control between emitter and ground electrode. PMID:28773237

  18. Multi-quadrant biopsy technique improves diagnostic ability in large heterogeneous renal masses. Abel EJ, Heckman JE, Hinshaw L, Best S, Lubner M, Jarrard DF, Downs TM, Nakada SY, Lee FT Jr, Huang W, Ziemlewicz T.J Urol. 2015 Oct;194(4):886-91. [Epub 2015 Mar 30]. doi: 10.1016/j.juro.2015.03.106.

    PubMed

    Jay, Raman; Heckman, J E; Hinshaw, L; Best, S; Lubner, M; Jarrard, D F; Downs, T M; Nakada, S Y; Lee, F T; Huang, W; Ziemlewicz, T

    2017-03-01

    Percutaneous biopsy obtained from a single location is prone to sampling error in large heterogeneous renal masses, leading to nondiagnostic results or failure to detect poor prognostic features. We evaluated the accuracy of percutaneous biopsy for large renal masses using a modified multi-quadrant technique vs. a standard biopsy technique. Clinical and pathological data for all patients with cT2 or greater renal masses who underwent percutaneous biopsy from 2009 to 2014 were reviewed. The multi-quadrant technique was defined as multiple core biopsies from at least 4 separate solid enhancing areas in the tumor. The incidence of nondiagnostic findings, sarcomatoid features and procedural complications was recorded, and concordance between biopsy specimens and nephrectomy pathology was compared. A total of 122 biopsies were performed for 117 tumors in 116 patients (46 using the standard biopsy technique and 76 using the multi-quadrant technique). Median tumor size was 10cm (IQR: 8-12). Biopsy was nondiagnostic in 5 of 46 (10.9%) standard and 0 of 76 (0%) multi-quadrant biopsies (P = 0.007). Renal cell carcinoma was identified in 96 of 115 (82.0%) tumors and nonrenal cell carcinoma tumors were identified in 21 (18.0%). One complication occurred using the standard biopsy technique and no complications were reported using the multi-quadrant technique. Sarcomatoid features were present in 23 of 96 (23.9%) large renal cell carcinomas studied. Sensitivity for identifying sarcomatoid features was higher using the multi-quadrant technique compared to the standard biopsy technique at 13 of 15 (86.7%) vs. 2 of 8 (25.0%) (P = 0.0062). The multi-quadrant percutaneous biopsy technique increases the ability to identify aggressive pathological features in large renal tumors and decreases nondiagnostic biopsy rates. Copyright © 2017. Published by Elsevier Inc.

  19. Glaucoma anterior chamber morphometry based on optical Scheimpflug images.

    PubMed

    Alonso, Ruiz Simonato; Ambrósio Junior, Renato; Paranhos Junior, Augusto; Sakata, Lisandro Massanori; Ventura, Marcelo Palis

    2010-01-01

    To compare the performance of gonioscopy and noncontact morphometry with anterior chamber tomography (High Resolution Pentacam - HR) using optical Scheimpflug images in the evaluation of the anterior chamber angle (ACA). Transversal study. 112 eyes from 74 subjects evaluated at the Glaucoma Department, Fluminense Federal University, underwent gonioscopy and Pentacam HR. Using gonioscopy, the ACA was graded using the Shaffer Classification (SC) by a single experienced examiner masked to the Pentacam HR findings. Narrow angle was determined in eyes in which the posterior trabecular meshwork could not be seen in two or more quadrants on non-indentation gonioscopy (SC Grade 2 or less). Pentacam HR images of the nasal and temporal quadrants were evaluated by custom software to automatically obtain anterior chamber measurements, such as: anterior chamber angle (ACA), anterior chamber volume (ACV) and anterior chamber depth (ACD). Based on gonioscopy results, 74 (60.07%) eyes of patients classified as open-angle (SC 3 and 4) and 38 (33.93%) eyes of patients classified as narrow-angle (SC 1 and 2). Noncontact morphometry with Scheimpflug images revealed a mean ACA of 39.20 ± 5.31 degrees for open-angle and 21.18 ± 7.98 degrees for narrow-angle. The open-angle group showed significant greater ACV and ACD values when compared to narrow-angle group (ACV of 193 ± 36 mm³ vs. 90 ± 25 mm³, respectively, p<0.001; and ACD of 3,09 ± 0,42 mm vs. 1,55 ± 0,64 mm, respectively, p<0.0001.). In screening eyes with open-angle and narrow-angle with the Pentacam ACA of 20º (SC Grade 2) using the ROC curves, the analysis showed 52.6% of sensitivity and 100% of specificity. The Pentacam showed ability in detecting eyes at risk for angle closure analyzing ACV and ACD.

  20. Longitudinal analysis on human cervical tissue using optical coherence tomography (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Gan, Yu; Yao, Wang; Myers, Kristin M.; Vink, Joy-Sarah Y.; Wapner, Ronald J.; Hendon, Christine P.

    2017-02-01

    Uterine cervical collagen fiber network is vital to the normal cervical function in pregnancy. Previously, we presented an orientation estimation method to enable dispersion analysis on a single axial slice of human cervical tissue obtained from the upper half of cervix using optical coherence tomography (OCT). How the collagen fiber network structure changes from the internal os (top of the cervix which meets the uterus) to external os (bottom of cervix which extends into the vagina), remains unknown due to depth penetration limitations of OCT. To establish a collagen fiber directionality "map" of the entire cervix, we imaged serial axial slices of human NP (n=11) and PG (n=2) cervical tissue obtained from the internal to external os using Institutional Review Board approved protocols at Columbia University Medical Center. Each slice was divided into four quadrants. In each quadrant, we stitched multiple overlapped OCT volumes and analyzed the en face images that were parallel to the surface. A pixel-wise directionality map was generated. We analyzed fiber trend by measuring the mean angles and quantified dispersion by calculating the standard deviation of the fiber direction over a region of 400 μm × 400 μm. For the initial four samples, our analysis confirms a circumferential fiber pattern in the outer region of slices at all depths. We found that the standard deviation close to internal os showed no significance to the standard deviation close to external os (p>0.05), indicating comparable dispersion.

  1. An Off-Axis Four-Quadrant Phase Mask (FQPM) Coronagraph for Palomar: High-Contrast Near Bright Stars Imager

    NASA Technical Reports Server (NTRS)

    Haguenauer, Pierre; Serabyn, Eugene; Bloemhof, Eric E.; Troy, Mitchell; Wallace, James K.; Koresko, Chris D.; Mennesson, Bertrand

    2005-01-01

    Direct detection of planets around nearby stars requires the development of high-contrast imaging techniques because of the high difference between their respective fluxes. This led us to test a new coronagraphic approach based on the use of phase mask instead of dark occulting ones. Combined with high-level wavefront correction on an unobscured off-axis section of a large telescope, this method allows imaging very close to the star. Calculations indicate that for a given ground-based on-axis telescope, use of such an off-axis coronagraph provides a near-neighbor detection capability superior to that of a traditional coronagraph utilizing the full telescope aperture. Setting up a laboratory experiment working in near infrared allowed us to demonstrate the principle of the method, and a rejection of 2000:1 has already been achieved.

  2. Barium appendicitis after upper gastrointestinal imaging.

    PubMed

    Novotny, Nathan M; Lillemoe, Keith D; Falimirski, Mark E

    2010-02-01

    Barium appendicitis (BA) is a rarely seen entity with fewer than 30 reports in the literature. However, it is a known complication of barium imaging. To report a case of BA in a patient whose computed tomography (CT) scan was initially read as foreign body ingestion. An 18-year-old man presented with right lower quadrant pain after upper gastrointestinal imaging 2 weeks prior. A CT scan was obtained of his abdomen and pelvis that revealed a finding that was interpreted as a foreign body at the area of the terminal ileum. A plain X-ray study of the abdomen revealed radiopaque appendicoliths. Pathology confirmed the diagnosis of barium appendicitis. BA is a rare entity and the pathogenesis is unclear. Shorter intervals between barium study and presentation with appendicitis usually correlate with fewer complications. Copyright (c) 2010 Elsevier Inc. All rights reserved.

  3. Mean Glandular dose coefficients (DgN) for x-ray spectra used in contemporary breast imaging systems

    PubMed Central

    Nosratieh, Anita; Hernandez, Andrew; Shen, Sam Z.; Yaffe, Martin J.; Seibert, J. Anthony; Boone, John M.

    2015-01-01

    Purpose To develop tables of normalized glandular dose coefficients DgN for a range of anode–filter combinations and tube voltages used in contemporary breast imaging systems. Methods Previously published mono-energetic DgN values were used with various spectra to mathematically compute DgN coefficients. The tungsten anode spectra from TASMICS were used; Molybdenum and Rhodium anode-spectra were generated using MCNPx Monte Carlo code. The spectra were filtered with various thicknesses of Al, Rh, Mo or Cu. An initial HVL calculation was made using the anode and filter material. A range of the HVL values was produced with the addition of small thicknesses of polymethyl methacrylate (PMMA) as a surrogate for the breast compression paddle, to produce a range of HVL values at each tube voltage. Using a spectral weighting method, DgN coefficients for the generated spectra were calculated for breast glandular densities of 0%, 12.5%, 25%, 37.5%, 50% and 100% for a range of compressed breast thicknesses from 3 to 8 cm. Results Eleven tables of normalized glandular dose (DgN) coefficients were produced for the following anode/filter combinations: W + 50 μm Ag, W + 500 μm Al, W + 700 μm Al, W + 200 μm Cu, W + 300 μm Cu, W + 50 μm Rh, Mo + 400 μm Cu, Mo + 30 μm Mo, Mo + 25 μm Rh, Rh + 400 μm Cu and Rh + 25 μm Rh. Where possible, these results were compared to previously published DgN values and were found to be on average less than 2% different than previously reported values. Conclusion Over 200-pages of DgN coefficients were computed for modeled x-ray system spectra that are used in a number of new breast imaging applications. The reported values were found to be in excellent agreement when compared to published values. PMID:26348995

  4. Stereo View of Martian Rock Target 'Funzie'

    NASA Image and Video Library

    2018-02-08

    The surface of the Martian rock target in this stereo image includes small hollows with a "swallowtail" shape characteristic of some gypsum crystals, most evident in the lower left quadrant. These hollows may have resulted from the original crystallizing mineral subsequently dissolving away. The view appears three-dimensional when seen through blue-red glasses with the red lens on the left. The scene spans about 2.5 inches (6.5 centimeters). This rock target, called "Funzie," is near the southern, uphill edge of "Vera Rubin Ridge" on lower Mount Sharp. The stereo view combines two images taken from slightly different angles by the Mars Hand Lens Imager (MAHLI) camera on NASA's Curiosity Mars rover, with the camera about 4 inches (10 centimeters) above the target. Fig. 1 and Fig. 2 are the separate "right-eye" and "left-eye" images, taken on Jan. 11, 2018, during the 1,932nd Martian day, or sol, of the rover's work on Mars. Right-eye and left-eye images are available at https://photojournal.jpl.nasa.gov/catalog/PIA22212

  5. Adding polarimetric imaging to depth map using improved light field camera 2.0 structure

    NASA Astrophysics Data System (ADS)

    Zhang, Xuanzhe; Yang, Yi; Du, Shaojun; Cao, Yu

    2017-06-01

    Polarization imaging plays an important role in various fields, especially for skylight navigation and target identification, whose imaging system is always required to be designed with high resolution, broad band, and single-lens structure. This paper describe such a imaging system based on light field 2.0 camera structure, which can calculate the polarization state and depth distance from reference plane for every objet point within a single shot. This structure, including a modified main lens, a multi-quadrants Polaroid, a honeycomb-liked micro lens array, and a high resolution CCD, is equal to an "eyes array", with 3 or more polarization imaging "glasses" in front of each "eye". Therefore, depth can be calculated by matching the relative offset of corresponding patch on neighboring "eyes", while polarization state by its relative intensity difference, and their resolution will be approximately equal to each other. An application on navigation under clear sky shows that this method has a high accuracy and strong robustness.

  6. A Population-Based Assessment of the Agreement Between Grading of Goniophotographic Images and Gonioscopy in the Chinese-American Eye Study (CHES).

    PubMed

    Murakami, Yohko; Wang, Dandan; Burkemper, Bruce; Lin, Shan C; Varma, Rohit

    2016-08-01

    To compare grading of goniophotographic images and gonioscopy in assessing the iridocorneal angle. In a population-based, cross-sectional study, participants underwent gonioscopy and goniophotographic imaging during the same visit. The iridocorneal angle was classified as closed if the posterior trabecular meshwork could not be seen. A single masked observer graded the goniophotographic images, and each eye was classified as having angle closure based on the number of closed quadrants. Agreement between the methods was analyzed by calculating kappa (κ) and first-order agreement coefficient (AC1) statistics and comparison of area under receiver operating characteristic curves (AUC). A total of 4149 Chinese Americans (3994 eyes) were included in this study. The agreement for angle closure diagnosis between gonioscopy and EyeCam was moderate to excellent (κ = 0.60, AC1 0.90, AUC 0.76-0.80). Detection of iridocorneal angle closure based on goniophotographic imaging shows moderate to very good agreement with angle closure assessment using gonioscopy.

  7. Formation of self-ordered porous anodized alumina template for growing tungsten trioxide nanowires

    NASA Astrophysics Data System (ADS)

    Hussain, Tajamal; Shah, Asma Tufail; Shehzad, Khurram; Mujahid, Adnan; Farooqi, Zahoor Hussain; Raza, Muhammad Hamid; Ahmed, Mirza Nadeem; Nisa, Zaib Un

    2015-12-01

    Uniform porous anodized aluminum oxide (AAO) membrane has been synthesized by two-step anodization for fabricating tungsten trioxide (WO3) nanowires. Under assayed conditions, uniform porous structure of alumina (Al2O3) membrane with long range ordered hexagonal arrangements of nanopores was achieved. The self-assembled template possesses pores of internal diameter of 50 nm and interpore distance ( d int) of 80 nm with a thickness of about 80 µm, i.e., used for fabrication of nanostructures. WO3 nanowires have been fabricated by simple electroless deposition method inside Al2O3 nanopores. SEM images show tungsten trioxide nanowire with internal diameter of about 50 nm, similar to porous diameter of AAO template. XRD results showed that nanowires exist in cubic crystalline state with minor proportion of monoclinic phase.

  8. Surface modification of graphene using HBC-6ImBr in solution-processed OLEDs

    NASA Astrophysics Data System (ADS)

    Cheng, Tsung-Chin; Ku, Ting-An; Huang, Kuo-You; Chou, Ang-Sheng; Chang, Po-Han; Chang, Chao-Chen; Yue, Cheng-Feng; Liu, Chia-Wei; Wang, Po-Han; Wong, Ken-Tsung; Wu, Chih-I.

    2018-01-01

    In this work, we report a simple method for solution-processed organic light emitting devices (OLEDs), where single-layer graphene acts as the anode and the hexa-peri-hexabenzocoronene exfoliating agent (HBC-6ImBr) provides surface modification. In SEM images, the PEDOT:PSS solution fully covered the graphene electrode after coating with HBC-6ImBr. The fabricated solution-processed OLEDs with a single-layer graphene anode showed outstanding brightness at 3182 cd/m2 and current efficiency up to 6 cd/A which is comparable to that of indium tin oxide films, and the OLED device brightness performance increases six times compared to tri-layer graphene treated with UV-Ozone at the same driving voltage. This method can be used in a wide variety of solution-processed organic optoelectronics on surface-modified graphene anodes.

  9. Relation of sound intensity and accuracy of localization.

    PubMed

    Farrimond, T

    1989-08-01

    Tests were carried out on 17 subjects to determine the accuracy of monaural sound localization when the head is not free to turn toward the sound source. Maximum accuracy of localization for a constant-volume sound source coincided with the position for maximum perceived intensity of the sound in the front quadrant. There was a tendency for sounds to be perceived more often as coming from a position directly toward the ear. That is, for sounds in the front quadrant, errors of localization tended to be predominantly clockwise (i.e., biased toward a line directly facing the ear). Errors for sounds occurring in the rear quadrant tended to be anticlockwise. The pinna's differential effect on sound intensity between front and rear quadrants would assist in identifying the direction of movement of objects, for example an insect, passing the ear.

  10. Interpersonal Subtypes and Therapy Response in Patients Treated for Posttraumatic Stress Disorder.

    PubMed

    König, Julia; Onnen, Margarete; Karl, Regina; Rosner, Rita; Butollo, Willi

    2016-01-01

    Interpersonal traits may influence psychotherapy success. One way of conceptualizing such traits is the interpersonal circumplex model. In this study, we analyse interpersonal circumplex data, assessed with the Inventory of Interpersonal Problems (Horowitz, Strauß, & Kordy, 1994) from a randomized study with 138 patients suffering from posttraumatic stress disorder after trauma in adulthood. The study compared cognitive processing therapy and dialogical exposure therapy, a Gestalt-based intervention. We divided the interpersonally heterogeneous sample according to the quadrants of the interpersonal circumplex. The division into quadrants yielded subgroups that did not differ in their general psychological distress, but the cold-submissive quadrant tended to exhibit higher posttraumatic stress disorder symptom severity and interpersonal distress than the other three. There was also a trend for patients in different quadrants to be affected differently by the treatments. Correlation analyses supported these results: in cognitive processing therapy, more dominant patients had more successful therapies, while in dialogical exposure therapy, success was not correlated with interpersonal style. Results indicate that especially patients with cold interpersonal styles profited differentially from the two treatments offered. Dividing samples according to the interpersonal circumplex quadrants seems promising. Interpersonal traits may contribute to psychotherapy outcome. Dividing the sample according to the quadrants of the interpersonal circumplex, as opposed to cluster analysis, yielded promising results. Patients higher in dominance fared better with cognitive processing therapy, while interpersonal style had no correlations with therapy success in dialogical exposure therapy. Copyright © 2015 John Wiley & Sons, Ltd.

  11. Simulation, optimization and testing of a novel high spatial resolution X-ray imager based on Zinc Oxide nanowires in Anodic Aluminium Oxide membrane using Geant4

    NASA Astrophysics Data System (ADS)

    Esfandi, F.; Saramad, S.

    2015-07-01

    In this work, a new generation of scintillator based X-ray imagers based on ZnO nanowires in Anodized Aluminum Oxide (AAO) nanoporous template is characterized. The optical response of ordered ZnO nanowire arrays in porous AAO template under low energy X-ray illumination is simulated by the Geant4 Monte Carlo code and compared with experimental results. The results show that for 10 keV X-ray photons, by considering the light guiding properties of zinc oxide inside the AAO template and suitable selection of detector thickness and pore diameter, the spatial resolution less than one micrometer and the detector detection efficiency of 66% are accessible. This novel nano scintillator detector can have many advantages for medical applications in the future.

  12. Imaging radiation detector with gain

    DOEpatents

    Morris, C.L.; Idzorek, G.C.; Atencio, L.G.

    1982-07-21

    A radiation imaging device which has application in x-ray imaging. The device can be utilized in CAT scanners and other devices which require high sensitivity and low x-ray fluxes. The device utilizes cumulative multiplication of charge carriers on the anode plane and the collection of positive ion charges to image the radiation intensity on the cathode plane. Parallel and orthogonal cathode wire arrays are disclosed as well as a two-dimensional grid pattern for collecting the positive ions on the cathode.

  13. Imaging radiation detector with gain

    DOEpatents

    Morris, Christopher L.; Idzorek, George C.; Atencio, Leroy G.

    1984-01-01

    A radiation imaging device which has application in x-ray imaging. The device can be utilized in CAT scanners and other devices which require high sensitivity and low x-ray fluxes. The device utilizes cumulative multiplication of charge carriers on the anode plane and the collection of positive ion charges to image the radiation intensity on the cathode plane. Parallel and orthogonal cathode wire arrays are disclosed as well as a two-dimensional grid pattern for collecting the positive ions on the cathode.

  14. Boosting Power Density of Microbial Fuel Cells with 3D Nitrogen‐Doped Graphene Aerogel Electrode

    PubMed Central

    Yang, Yang; Liu, Tianyu; Zhang, Feng; Ye, Dingding; Liao, Qiang

    2016-01-01

    A 3D nitrogen‐doped graphene aerogel (N‐GA) as an anode material for microbial fuel cells (MFCs) is reported. Electron microscopy images reveal that the N‐GA possesses hierarchical porous structure that allows efficient diffusion of both bacterial cells and electron mediators in the interior space of 3D electrode, and thus, the colonization of bacterial communities. Electrochemical impedance spectroscopic measurements further show that nitrogen doping considerably reduces the charge transfer resistance and internal resistance of GA, which helps to enhance the MFC power density. Importantly, the dual‐chamber milliliter‐scale MFC with N‐GA anode yields an outstanding volumetric power density of 225 ± 12 W m−3 normalized to the total volume of the anodic chamber (750 ± 40 W m−3 normalized to the volume of the anode). These power densities are the highest values report for milliliter‐scale MFCs with similar chamber size (25 mL) under the similar measurement conditions. The 3D N‐GA electrode shows great promise for improving the power generation of MFC devices. PMID:27818911

  15. Active control of methanol carbonylation selectivity over Au/carbon anode by electrochemical potential.

    PubMed

    Funakawa, Akiyasu; Yamanaka, Ichiro; Otsuka, Kiyoshi

    2005-05-12

    Electrochemical oxidative carbonylation of methanol was studied over Au supported carbon anode in CO. The major carbonylation products were dimethyl oxalate (DMO) and dimethyl carbonate (DMC). The minor oxidation products were dimethoxy methane (DMM) and methyl formate (MF) from methanol and CO(2). Influences of various reaction conditions were studied on carbonylation activities and selectivities. The selectivities to DMO and DMC can be controlled by the electrochemical potential. Electrocatalysis of Au/carbon anode was studied by cyclic voltammetry (CV), stoichiometric reactions among Au(3+), methanol, and CO, and UV-vis spectra. The Au/carbon anode was characterized by XRD, SEM, and BE images before and after the carbonylation. These experimental facts strongly suggest that transition of oxidation states of Au affects changing of the carbonylation selectivities to DMO and DMC. Au(0) is the active species for the selective DMO formation by direct electrochemical carbonylation at low potentials (<+1.2 V (Ag/AgCl)). On the other hand, Au(3+) is the active spices for the selective DMC formation by indirect electrochemical carbonylation through Au(3+)/Au(+) redox at high potentials (>+1.3 V).

  16. Effect of Processing Parameters on Pore Structure and Thickness of Anodic Aluminum Oxide (AAO) Tubular Membranes.

    PubMed

    Belwalkar, A; Grasing, E; Van Geertruyden, W; Huang, Z; Misiolek, W Z

    2008-07-01

    Nanoporous anodic aluminum oxide (AAO) tubular membranes were fabricated from aluminum alloy tubes in sulfuric and oxalic acid electrolytes using a two-step anodization process. The membranes were investigated for characteristics such as pore size, interpore distance and thickness by varying applied voltage and electrolyte concentration. Morphology of the membranes was examined using light optical and scanning electron microscopy and characterized using ImageJ software. Results showed that membranes having narrow pore size and uniform pore distribution with parallel channel arrays were obtained. The pore sizes were ranging from 14 to 24 nm and the wall thicknesses as high as 76 microm. It was found that the pore size increased in direct proportion with the applied voltage and inversely with the electrolyte concentration while the interpore distance increased linearly with the applied voltage. It was also observed that increase in acid concentration increased tubular membrane wall thickness that improved mechanical handling. By using anodic alumina technology, robust ceramic tubes with uniformly distributed pore-structure and parallel nano-channels of lengths and sizes practical for industrial applications were reliably produced in quantity.

  17. Effect of Processing Parameters on Pore Structure and Thickness of Anodic Aluminum Oxide (AAO) Tubular Membranes

    PubMed Central

    Belwalkar, A.; Grasing, E.; Huang, Z.; Misiolek, W.Z.

    2008-01-01

    Nanoporous anodic aluminum oxide (AAO) tubular membranes were fabricated from aluminum alloy tubes in sulfuric and oxalic acid electrolytes using a two-step anodization process. The membranes were investigated for characteristics such as pore size, interpore distance and thickness by varying applied voltage and electrolyte concentration. Morphology of the membranes was examined using light optical and scanning electron microscopy and characterized using ImageJ software. Results showed that membranes having narrow pore size and uniform pore distribution with parallel channel arrays were obtained. The pore sizes were ranging from 14 to 24 nm and the wall thicknesses as high as 76 µm. It was found that the pore size increased in direct proportion with the applied voltage and inversely with the electrolyte concentration while the interpore distance increased linearly with the applied voltage. It was also observed that increase in acid concentration increased tubular membrane wall thickness that improved mechanical handling. By using anodic alumina technology, robust ceramic tubes with uniformly distributed pore-structure and parallel nano-channels of lengths and sizes practical for industrial applications were reliably produced in quantity. PMID:19578471

  18. X-ray diagnostic development for measurement of electron deposition to the SABRE anode

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lash, J.S.; Derzon, M.S.; Cuneo, M.E.

    Extraction applied-B ion diodes are under development on the SABRE (6 MV, 250 kA) accelerator at Sandia. The authors are assessing this technology for the production of high brightness lithium ion beams for inertial confinement fusion. Electron loss physics is a focus of effort since electron sheath physics affects ion beam divergence, ion beam purity, and diode impedance. An x-ray slit-imaging diagnostic is under development for detection of x-rays produced during electron deposition to the anode. This diagnostic will aid in the correlation of electron deposition to ion production to better understand the ion diode physics. The x-ray detector consistsmore » of a filter pack, scintillator and optical fiber array that is streaked onto a CCD camera. Current orientation of the diagnostic provides spatial information across the anode radius at three different azimuths or at three different x-ray energy cuts. The observed x-ray emission spectrum can then be compared to current modeling efforts examining electron deposition to the anode.« less

  19. Coralloid-like Nanostructured c-nSi/SiOx@Cy Anodes for High Performance Lithium Ion Battery.

    PubMed

    Zhuang, Xianhuan; Song, Pingan; Chen, Guorong; Shi, Liyi; Wu, Yuan; Tao, Xinyong; Liu, Hongjiang; Zhang, Dengsong

    2017-08-30

    Balancing the size of the primary Si unit and void space is considered to be an effective approach for developing high performance silicon-based anode materials and is vital to create a lithium ion battery with high energy density. We herein have demonstrated the facile fabrication of coralloid-like nanostructured silicon composites (c-nSi/SiO x @Cy) via sulfuric acid etching the Al 60 Si 40 alloy, followed by a surface growth carbon layer approach. The HRTEM images of pristine and cycled c-nSi/SiO x @Cy show that abundant nanoscale internal pores and the continuous conductive carbon layer effectively avoid the pulverization and agglomeration of Si units during multiple cycles. It is interesting that the c-nSi/SiO x @C 4.0 anode exhibits a high initial Coulombic efficiency of 85.53%, and typical specific capacity of over 850 mAh g -1 after deep 500 cycles at a current density of 1 A g -1 . This work offers a facile strategy to create silicon-based anodes consisting of highly dispersed primary nano-Si units.

  20. X-ray emission scaling law from a plasma focus with different anode tip materials (Cu, Mo, and W)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sharif, M.; Ahmad, S.; Zakaullah, M.

    X-ray emission from a 2.3-5.3 kJ Mather-type plasma focus [Phys. Fluids 7, 5 (1964)] employing copper, molybdenum, and tungsten anode tip is studied. Argon is used as a working gas. Characteristic Cu K{alpha} and Mo K-series emission and their ratio to the continuous x-rays are determined. From the variation of the x-ray yield data with filling pressure at different charging voltages, scaling laws are obtained. X-ray pinhole images demonstrate that a significant amount of x-ray emission is from the anode tip. The comparison of the ratio of characteristic to continuum radiation for copper anode with typical x-ray tube data revealsmore » that the contribution of very high energy electron beam from the focus region for x-ray generation through thick target bremsstrahlung mechanism is not significant. Rather, electrons with energy of the order of, or even less than, the charging voltage are responsible for bulk of the x-ray emission.« less

  1. White Paper AGA: Advanced Imaging in Barrett's Esophagus.

    PubMed

    Sharma, Prateek; Brill, Joel; Canto, Marcia; DeMarco, Daniel; Fennerty, Brian; Gupta, Neil; Laine, Loren; Lieberman, David; Lightdale, Charles; Montgomery, Elizabeth; Odze, Robert; Tokar, Jeffrey; Kochman, Michael

    2015-12-01

    Enhanced imaging technologies such as narrow band imaging, flexible spectral imaging color enhancement, i-Scan, confocal laser endomicroscopy, and optical coherence tomography are readily available for use by endoscopists in routine clinical practice. In November 2014, the American Gastroenterological Association's Center for GI Innovation and Technology conducted a 2-day workshop to discuss endoscopic image enhancement technologies, focusing on their role in 2 specific clinical conditions (colon polyps and Barrett's esophagus) and on issues relating to training and implementation of these technologies (white papers). Although the majority of the studies that use enhanced imaging technologies have been positive, these techniques ideally need to be validated in larger cohorts and in community centers. As it stands today, detailed endoscopic examination with high-definition white-light endoscopy and random 4-quadrant biopsy remains the standard of care. However, the workshop panelists agreed that in the hands of endoscopists who have met the preservation and incorporation of valuable endoscopic innovation thresholds (diagnostic accuracy) with enhanced imaging techniques (specific technologies), use of the technique in Barrett's esophagus patients is appropriate. Copyright © 2015 AGA Institute. Published by Elsevier Inc. All rights reserved.

  2. Field study of mussel impact on turbulent structure in the internal boundary layer of a low energetic deep lake

    NASA Astrophysics Data System (ADS)

    Wang, B.; Liao, Q.; Bootsma, H. A.; Troy, C. D.

    2013-12-01

    The impact of invasive mussels on Great Lake aquatic ecosystem attracted wide attentions. Their strong ability on phytoplankton consumption and impact on nutrient and oxygen dynamics greatly change the behavior of benthic communities. The hydrodynamics in the internal boundary layer (IBL) at low energetic deep lakes is of great importance on food delivery. Meantime, the filtration activities of mussels provide feedback to turbulence structure in the IBL. This filed study was carried out at the 55 meters station in Lake Michigan using an in situ PIV system to measure high resolution turbulence immediately above the mussel bed. A HR acoustic profiler was used to measure three dimensional velocities within 1 meter above the bed. Quadrant-Hole analysis method was used to identify the organized structures of turbulent motion on contributing Reynolds shear stress. Sufficiently close to the mussels, turbulence sources were mostly contributed to flow-mussel interaction and mussel filtration, rather than shear production. Bed shear stress, friction velocity and bottom roughness were also investigated. Our results suggest measurement should be made in the IBL to accurate estimate the bed friction and erodability. A particle concentration depletion layer was observed within 7~8 centimeters above the mussel bed. Significant enhancement of turbulent mixing was found due to filtration activities, which tends to help food supply for benthic mussels in low energetic aquatic systems A sample PIV image superimposed with 2-D velocity map Vertical profiles of (a) fraction for each quadrant event (b) conditional averaged Reynolds shear stress for each quadrant event. Two dash lines represent z = 1.3 cm and 3.6 cm.

  3. Retinal vessel oxygen saturation in a healthy young Chinese population.

    PubMed

    Yang, Wei; Fu, Yue; Dong, Yanmin; Lin, Leilei; Huang, Xia; Li, Yujie; Lin, Xiaofeng; Gao, Qianying

    2016-06-01

    To measure retinal vessel oxygen saturation in a healthy young Chinese population and to determine the effects of multiple factors (gender, age, dioptre, vessel diameter and ocular perfusion pressure - OPP) on retinal oxygen saturation. A total of 126 healthy Chinese individuals aged from 19 to 30 were included in this study. A retinal oximeter (Oxymap T1) was used to measure retinal vessel oxygen saturation by retinal imaging at two different wavelengths. The mean retinal vessel oxygen saturation (Sat_O2 ) of arterioles, venules and arteriovenous (AV) difference overall and in four separate quadrants were measured. Intra-ocular pressure, blood pressure, finger pulse oximetry value, vessel diameter and dioptre were also measured. The correlations between OPP and dioptre, OPP and vessel diameter, and dioptre and vessel diameter were analysed. And the effects of multiple factors on the retinal oxygen saturation were analysed. The mean oxygen saturation was 93.2 ± 6.3% in the retinal arterioles, 60.4 ± 5.3% in venules and 32.9 ± 6.4% in AV difference. The temporal quadrants had lower measurements of arteriolar and venular oxygen saturation and AV difference compared with nasal quadrants (p < 0.001). The oxygen saturation of the arterioles, venules and AV difference were unaffected by any unique factor. Arteriolar and venular retinal oxygen saturation correlated negatively with the product of dioptre and OPP. Arteriolar retinal oxygen saturation correlated positively with the product of dioptre and vessel diameter. This study provided a normal reference of Sat_O2 in healthy young Chinese individuals. It was a reflection of the normal state of retinal oxygen metabolism affected by several factors. © 2016 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

  4. Radiopacity of Mineral Trioxide Aggregate with and without Inclusion of Silver Nanoparticles.

    PubMed

    Mendes, Mariana Ss; Resende, Leonardo D; Pinto, Cláudia A; Raldi, Denise P; Cardoso, Flavia Gr; Habitante, Sandra M

    2017-06-01

    The aim of this study was to investigate the inclusion of silver nanoparticles (Ag NPs) in the mineral trioxide aggregate (MTA) composition to know which changes will result in the radiopacity of the material. The experiment was performed according to the American National Standard Institute/American Dental Association specification no. 57/2000 and ISO 6876/2001. Five plates with five holes measuring 1 mm in depth and 5 mm in internal diameter were filled according to the different experimental groups as follows: white mineral trioxide aggregate (WMTA) + NP50 - W MTA with liquid Ag NP 50 ppm, WMTA + NP30 - W MTA with liquid Ag NP 30 ppm, WMTA + NP22 - W MTA with liquid Ag NP 22 ppm, WMTA + NPP - white MTA with liquid Ag NP and powder 1%, WMTA (control). After filling the plates, they were kept in an incubator at 37°C in relative humidity for setting. Each sample was positioned along an aluminum step-wedge placed above the Opteo digital sensor system. The image was divided into four quadrants, and three readings were made for each quadrant to render the average of each quadrant. The resulting data were submitted to Kruskal-Wallis and Dunn's tests. The results showed statistically significant differences between WMTA + NP30, WMTA + NP22, and WMTA + NPP interactions compared with WMTA (control) (p < 0.05). The radiopacity was in descending order: WMTA + NPP, WMTA + NP22, WMTA + NP30, MTA + NP50, and WMTA. Silver NPs changed the radiopacity of WMTA, being more evident in WMTA + NP powder at 1% weight. The low radiopacity of MTA makes it difficult for any radiographic observation. The Ag NPs appear as an alternative, being an excellent radiopacifier as they have excellent antimicrobial property and relatively low toxicity.

  5. A Highly Linear and Wide Input Range Four-Quadrant CMOS Analog Multiplier Using Active Feedback

    NASA Astrophysics Data System (ADS)

    Huang, Zhangcai; Jiang, Minglu; Inoue, Yasuaki

    Analog multipliers are one of the most important building blocks in analog signal processing circuits. The performance with high linearity and wide input range is usually required for analog four-quadrant multipliers in most applications. Therefore, a highly linear and wide input range four-quadrant CMOS analog multiplier using active feedback is proposed in this paper. Firstly, a novel configuration of four-quadrant multiplier cell is presented. Its input dynamic range and linearity are improved significantly by adding two resistors compared with the conventional structure. Then based on the proposed multiplier cell configuration, a four-quadrant CMOS analog multiplier with active feedback technique is implemented by two operational amplifiers. Because of both the proposed multiplier cell and active feedback technique, the proposed multiplier achieves a much wider input range with higher linearity than conventional structures. The proposed multiplier was fabricated by a 0.6µm CMOS process. Experimental results show that the input range of the proposed multiplier can be up to 5.6Vpp with 0.159% linearity error on VX and 4.8Vpp with 0.51% linearity error on VY for ±2.5V power supply voltages, respectively.

  6. Low-temperature crystallization of anodized TiO2 nanotubes at the solid-gas interface and their photoelectrochemical properties

    NASA Astrophysics Data System (ADS)

    Liu, Jing; Liu, Zhaoyue; Zhang, Tierui; Zhai, Jin; Jiang, Lei

    2013-06-01

    TiO2 nanotubular arrays formed by electrochemical anodization have attracted significant attention for photoelectrochemical applications that utilize solar energy. However, the as-anodized TiO2 nanotubes are amorphous, and need to be crystallized by high-temperature thermal annealing. Herein, we describe a low-temperature hydrothermal solid-gas route to crystallize TiO2 nanotubes. In this process, the as-anodized TiO2 hydroxo nanotubes are dehydrated to yield anatase phase via solid-gas interface reaction in an autoclave at a temperature of less than 180 °C. The solid-gas interface reaction alleviates the collapse of as-anodized TiO2 nanotubes during hydrothermal process efficiently. Compared with the common thermal annealing at the same temperature but at atmospheric pressure, the hydrothermal route improves the photocurrent density of TiO2 nanotubes by ~10 times in KOH electrolyte. The duration of the hydrothermal reaction has a substantial effect on the photoelectrochemical properties of TiO2 nanotubes, which is ascribed to the synergetic effect between the crystallization and structural evolution. Electron donors can further suppress the charge recombination in the low-temperature crystallized TiO2 nanotubes and boost the photocurrent density by ~120%.TiO2 nanotubular arrays formed by electrochemical anodization have attracted significant attention for photoelectrochemical applications that utilize solar energy. However, the as-anodized TiO2 nanotubes are amorphous, and need to be crystallized by high-temperature thermal annealing. Herein, we describe a low-temperature hydrothermal solid-gas route to crystallize TiO2 nanotubes. In this process, the as-anodized TiO2 hydroxo nanotubes are dehydrated to yield anatase phase via solid-gas interface reaction in an autoclave at a temperature of less than 180 °C. The solid-gas interface reaction alleviates the collapse of as-anodized TiO2 nanotubes during hydrothermal process efficiently. Compared with the common thermal annealing at the same temperature but at atmospheric pressure, the hydrothermal route improves the photocurrent density of TiO2 nanotubes by ~10 times in KOH electrolyte. The duration of the hydrothermal reaction has a substantial effect on the photoelectrochemical properties of TiO2 nanotubes, which is ascribed to the synergetic effect between the crystallization and structural evolution. Electron donors can further suppress the charge recombination in the low-temperature crystallized TiO2 nanotubes and boost the photocurrent density by ~120%. Electronic supplementary information (ESI) available: Morphology images of TiO2 nanotubular arrays crystallized by hydrothermal solid-liquid reaction at 130 °C, 160 °C and 180 °C for 4 h. Cross-sectional image of TiO2 nanotubular arrays prepared by anodizing Ti foil at 20 V for 20 min in 0.5 wt% HF solution followed by drying in air at 100 °C for 1 h; Photocurrent density-potential curves of TiO2 nanotubular arrays crystallized by thermal annealing at 450 °C and atmospheric pressure for 4 h. See DOI: 10.1039/c3nr01286g

  7. Semiconductor crystal high resolution imager

    NASA Technical Reports Server (NTRS)

    Matteson, James (Inventor); Levin, Craig S. (Inventor)

    2011-01-01

    A radiation imaging device (10). The radiation image device (10) comprises a subject radiation station (12) producing photon emissions (14), and at least one semiconductor crystal detector (16) arranged in an edge-on orientation with respect to the emitted photons (14) to directly receive the emitted photons (14) and produce a signal. The semiconductor crystal detector (16) comprises at least one anode and at least one cathode that produces the signal in response to the emitted photons (14).

  8. Earth Observation

    NASA Image and Video Library

    2013-08-28

    ISS036-E-037747 (28 Aug. 2013) --- One of the Expedition 36 crew members aboard the International Space Station on Aug. 28 photographed this vertical image that shows much of Galveston County and a small portion of southeast Harris County, Texas. Gulf of Mexico waters take up the top half of the picture. Galveston Island runs from just left of center through center right of the image, and the Bolivar Peninsula, highly impacted by Hurricane Ike five years ago, is the land mass at left center. Galveston Bay takes up much of the lower left quadrant of the pictured area. The NASA Johnson Space Center, the normal work place for NASA astronauts Chris Cassidy and Karen Nyberg, currently onboard the orbital complex, is in the bottom portion of the frame.

  9. Antiallergic effect of the atomized extract of rhizome of Curcuma longa, flowers of Cordia lutea and leaves of Annona muricata

    PubMed Central

    Arroyo-Acevedo, Jorge; Franco-Quino, Cesar; Ruiz-Ramirez, Eliberto; Chávez-Asmat, Roberto; Anampa-Guzmán, Andrea; Raéz-González, Ernesto; Cabanillas-Coral, José

    2016-01-01

    Introduction Allergies are a problem that greatly affects the population, and hence the use of antiallergic medications is fairly widespread. However, these drugs have many adverse effects. The use of medicinal plants could be an option, but they need to be evaluated. Objective This study was designed to evaluate the antiallergic effect of the atomized extract of rhizome of Curcuma longa, flowers of Cordia lutea, and leaves of Annona muricata. Materials and methods Twenty-four New Zealand white albino rabbits were randomized into 2 groups. Group A received the atomized extract diluted in physiological saline (APS) and group B received it diluted in Freund’s adjuvant (FA). Then, the back of each rabbit was divided into 4 quadrants. The A-I quadrant received only physiological saline. The A-I quadrants of each rabbit conformed the PS group. The following 3 quadrants received the APS in 10 μg/mL, 100 μg/mL, and 1,000 μg/mL, respectively. The B-I quadrant received only FA. The B-I quadrants of each rabbit conformed the FA group. The following 3 quadrants received the AFA in 10 μg/mL, 100 μg/mL, and 1,000 μg/mL, respectively. The occurrence of erythema and edema was recorded according to the Draize scoring system and the primary irritation index. After 72 hours, biopsies were performed. Results The AFA group presented significantly less erythema and edema compared to the FA group (P<0.05). The histopathologic evaluation at 72 hours showed normal characteristics in the APS group. Conclusion Considering the clinical and histopathological signs, we conclude that the administration of the atomized extract of rhizome of C. longa, flowers of C. lutea, and leaves of A. muricata lacks antigenic effect but could have an antiallergenic effect in a model of dermal irritation in rabbits. PMID:27877047

  10. Antiallergic effect of the atomized extract of rhizome of Curcuma longa, flowers of Cordia lutea and leaves of Annona muricata.

    PubMed

    Arroyo-Acevedo, Jorge; Franco-Quino, Cesar; Ruiz-Ramirez, Eliberto; Chávez-Asmat, Roberto; Anampa-Guzmán, Andrea; Raéz-González, Ernesto; Cabanillas-Coral, José

    2016-01-01

    Allergies are a problem that greatly affects the population, and hence the use of antiallergic medications is fairly widespread. However, these drugs have many adverse effects. The use of medicinal plants could be an option, but they need to be evaluated. This study was designed to evaluate the antiallergic effect of the atomized extract of rhizome of Curcuma longa , flowers of Cordia lutea , and leaves of Annona muricata . Twenty-four New Zealand white albino rabbits were randomized into 2 groups. Group A received the atomized extract diluted in physiological saline (APS) and group B received it diluted in Freund's adjuvant (FA). Then, the back of each rabbit was divided into 4 quadrants. The A-I quadrant received only physiological saline. The A-I quadrants of each rabbit conformed the PS group. The following 3 quadrants received the APS in 10 μg/mL, 100 μg/mL, and 1,000 μg/mL, respectively. The B-I quadrant received only FA. The B-I quadrants of each rabbit conformed the FA group. The following 3 quadrants received the AFA in 10 μg/mL, 100 μg/mL, and 1,000 μg/mL, respectively. The occurrence of erythema and edema was recorded according to the Draize scoring system and the primary irritation index. After 72 hours, biopsies were performed. The AFA group presented significantly less erythema and edema compared to the FA group ( P <0.05). The histopathologic evaluation at 72 hours showed normal characteristics in the APS group. Considering the clinical and histopathological signs, we conclude that the administration of the atomized extract of rhizome of C. longa , flowers of C. lutea , and leaves of A. muricata lacks antigenic effect but could have an antiallergenic effect in a model of dermal irritation in rabbits.

  11. Survey of Nerve Fiber Layer Thickness in Anisometropic and Strabismic Amblyopia.

    PubMed

    Soltani Moghaddam, Reza; Medghalchi, Abdolreza; Alizadeh, Yousef

    2017-01-01

    . To investigate the effect of anisometropic and strabismic amblyopia on the nerve fiber layer thickness. This cross-sectional study was done on 54 amblyopic subjects, equally in both strabismic and anisometropic groups. The thickness otonerve fiber layer measured in superior, inferior, nasal, temporal quadrants and as a whole in both eyes of both groups. The means of thickness were compared in amblyopic and sound eyes. In strabismus group, the average nerve fiber layer thickness of the sound eye , in superior, inferior, nasal and temporal quadrants and as a whole were 113.23±14, 117.37±25, 68.96±6, 69.55±14 and 93.40±8 microns respectively. In amblyopic eyes of the same group, these measurements were 103.11±18, 67.74±11, and 69.59±16 and 89.59±12 microns in superior, inferior, nasal, temporal quadrants and as whole respectively. In anisometropic groups, the sound eye measurements were as 130.96±22, 129.07±29, 80.62±12, and 83.88±20 and 107.7±13 microns in superior, inferior, nasal and temporal quadrants and as a whole orderly. In amblyopic eyes of this group the mean thicknesses were 115.63±29, 133.15±25, 78.8±15, 80.2±16 and 109.17±21 microns in superior, inferior, nasal, temporal quadrants and as a whole respectively. Statistically, there were no significant differences between amblyopic and sound eyes (P>0.5). Our study did not support any significant change in a nerve fiber layer thickness of amblyopic patients; however, decreased thickness in superior and nasal quadrants of strabismic amblyopia and except inferior quadrant and as a whole. These measurements may be a clue for management and prognosis of amblyopia in old age.

  12. 59. VIEW FROM THE NORTHEAST IN THE NORTHEAST QUADRANT. GENERAL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    59. VIEW FROM THE NORTHEAST IN THE NORTHEAST QUADRANT. GENERAL VIEW OF THE RIGHT FLANK WALL. RIGHT SHOULDER ANGLE IS INCLUDED ON THE RIGHT SIDE OF THE PHOTOGRAPH. - Fort Sumter, Charleston, Charleston County, SC

  13. Illinois high-speed rail four-quadrant gate reliability assessment

    DOT National Transportation Integrated Search

    2009-10-01

    The Federal Railroad Administration (FRA) tasked the John A. Volpe National Transportation Systems Center (Volpe Center) to conduct a reliability analysis of the four-quadrant gate/vehicle detection equipment installed on the future high-speed rail (...

  14. 27 CFR 9.82 - Potter Valley.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... N.-T. 16 N. township line), the boundary runs northwest to the northeastern corner of quadrant 4, on the T. 18 N.-T. 17 N. township line; (2) Then west to the northwest corner of quadrant 1; (3) Then...

  15. 27 CFR 9.82 - Potter Valley.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... N.-T. 16 N. township line), the boundary runs northwest to the northeastern corner of quadrant 4, on the T. 18 N.-T. 17 N. township line; (2) Then west to the northwest corner of quadrant 1; (3) Then...

  16. Evaluation of Screening for Retinopathy of Prematurity by ROPtool or a Lay Reader.

    PubMed

    Abbey, Ashkan M; Besirli, Cagri G; Musch, David C; Andrews, Chris A; Capone, Antonio; Drenser, Kimberly A; Wallace, David K; Ostmo, Susan; Chiang, Michael; Lee, Paul P; Trese, Michael T

    2016-02-01

    To determine if (1) tortuosity assessment by a computer program (ROPtool, developed at the University of North Carolina, Chapel Hill, and Duke University, and licensed by FocusROP) that traces retinal blood vessels and (2) assessment by a lay reader are comparable with assessment by a panel of 3 retinopathy of prematurity (ROP) experts for remote clinical grading of vascular abnormalities such as plus disease. Validity and reliability analysis of diagnostic tools. Three hundred thirty-five fundus images of prematurely born infants. Three hundred thirty-five fundus images of prematurely born infants were obtained by neonatal intensive care unit nurses. A panel of 3 ROP experts graded 84 images showing vascular dilatation, tortuosity, or both and 251 images showing no evidence of vascular abnormalities. These images were sent electronically to an experienced lay reader who independently graded them for vascular abnormalities. The images also were analyzed using the ROPtool, which assigns a numerical value to the level of vascular abnormality and tortuosity present in each of 4 quadrants or sectors. The ROPtool measurements of vascular abnormalities were graded and compared with expert panel grades with a receiver operating characteristic (ROC) curve. Grades between human readers were cross-tabulated. The area under the ROC curve was calculated for the ROPtool, and sensitivity and specificity were computed for the lay reader. Measurements of vascular abnormalities by ROPtool and grading of vascular abnormalities by 3 ROP experts and 1 experienced lay reader. The ROC curve for ROPtool's tortuosity assessment had an area under the ROC curve of 0.917. Using a threshold value of 4.97 for the second most tortuous quadrant, ROPtool's sensitivity was 91% and its specificity was 82%. Lay reader sensitivity and specificity were 99% and 73%, respectively, and had high reliability (κ, 0.87) in repeated measurements. ROPtool had very good accuracy for detection of vascular abnormalities suggestive of plus disease when compared with expert physician graders. The lay reader's results showed excellent sensitivity and good specificity when compared with those of the expert graders. These options for remote reading of images to detect vascular abnormalities deserve consideration in the quest to use telemedicine with remote reading for efficient delivery of high-quality care and to detect infants requiring bedside examination. Copyright © 2016 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

  17. Chlamydia trachomatis-induced Fitz-Hugh-Curtis syndrome: a case report.

    PubMed

    Ekabe, Cyril Jabea; Kehbila, Jules; Njim, Tsi; Kadia, Benjamin Momo; Tendonge, Celestine Ntemlefack; Monekosso, Gottlieb Lobe

    2017-01-03

    Fitz-Hugh-Curtis syndrome is defined as perihepatitis associated with pelvic inflammatory disease. Chlamydia trachomatis is one of its most common aetiologies. This syndrome usually presents with right upper quadrant abdominal pain mimicking other hepatobiliary and gastrointestinal pathologies, hence, posing a diagnostic dilemma in settings with limited diagnostic tools. A 32 year old African female presented with acute right upper quadrant abdominal pain and vaginal discharge, for which she had previously received treatment in another health center with no improvement. Clinical and laboratory findings were suggestive of Fitz-Hugh-Curtis syndrome. Five days after treatment with oral doxycycline, the patient showed marked clinical improvement. Fitz-Hugh-Curtis syndrome is a common cause of right upper quadrant pain which is often under diagnosed in poor communities. Hence, it should be included as a differential diagnosis in patients presenting with right upper quadrant pain, especially in females of reproductive age.

  18. A novel active disturbance rejection based tracking design for laser system with quadrant photodetector

    NASA Astrophysics Data System (ADS)

    Manojlović, Stojadin M.; Barbarić, Žarko P.; Mitrović, Srđan T.

    2015-06-01

    A new tracking design for laser systems with different arrangements of a quadrant photodetector, based on the principle of active disturbance rejection control is suggested. The detailed models of quadrant photodetector with standard add-subtract, difference-over-sum and diagonal-difference-over-sum algorithms for displacement signals are included in the control loop. Target moving, non-linearity of a photodetector, parameter perturbations and exterior disturbances are treated as a total disturbance. Active disturbance rejection controllers with linear extended state observers for total disturbance estimation and rejection are designed. Proposed methods are analysed in frequency domain to quantify their stability characteristics and disturbance rejection performances. It is shown through simulations, that tracking errors are effectively compensated, providing the laser spot positioning in the area near the centre of quadrant photodetector where the mentioned algorithms have the highest sensitivity, which provides tracking of the manoeuvring targets with high accuracy.

  19. The Pasm Parallel Processing System: Design, Simulation, and Image Processing Applications. Volume 1

    DTIC Science & Technology

    1989-12-31

    was not funded and the author and other members of the PASM group turned their attention to related studies such as the further definition of the... Four such quadrants comprise the set of MCs and PEs. The logical PE i within each MC group is serviced by MSU i. Figure 1.9.3 shows that the MSUs are...instead of four Data Input Queues and with a 4-by-4 instead of a 2-by-2 crossbar switch could be designed. Studies indicate that the perfor- mance of a

  20. Hurricane Gonzalo 10/17

    NASA Image and Video Library

    2017-12-08

    On Oct. 17 at 15:15 UTC (11:15 a.m EDT) the MODIS instrument aboard NASA's Aqua satellite saw Hurricane Gonzalo's northern quadrant over Bermuda as it moved to landfall. ..Credit: NASA Goddard MODIS Rapid Response Team ..NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  1. Performance of a static-anode/flat-panel x-ray fluoroscopy system in a diagnostic strength magnetic field: a truly hybrid x-ray/MR imaging system.

    PubMed

    Fahrig, R; Wen, Z; Ganguly, A; DeCrescenzo, G; Rowlands, J A; Stevens, G M; Saunders, R F; Pelc, N J

    2005-06-01

    Minimally invasive procedures are increasing in variety and frequency, facilitated by advances in imaging technology. Our hybrid imaging system (GE Apollo flat panel, custom Brand x-ray static anode x-ray tube, GE Lunar high-frequency power supply and 0.5 T Signa SP) provides both x-ray and MR imaging capability to guide complex procedures without requiring motion of the patient between two distant gantries. The performance of the x-ray tube in this closely integrated system was evaluated by modeling and measuring both the response of the filament to an externally applied field and the behavior of the electron beam for field strengths and geometries of interest. The performance of the detector was assessed by measuring the slanted-edge modulation transfer function (MTF) and when placed at zero field and at 0.5 T. Measured resonant frequencies of filaments can be approximated using a modified vibrating beam model, and were at frequencies well below the 25 kHz frequency of our generator for our filament geometry. The amplitude of vibration was not sufficient to cause shorting of the filament during operation within the magnetic field. A simple model of electrons in uniform electric and magnetic fields can be used to estimate the deflection of the electron beam on the anode for the fields of interest between 0.2 and 0.5 T. The MTF measured at the detector and the DQE showed no significant difference inside and outside of the magnetic field. With the proper modifications, an x-ray system can be fully integrated with a MR system, with minimal loss of image quality. Any x-ray tube can be assessed for compatibility when placed at a particular location within the field using the models. We have also concluded that a-Si electronics are robust against magnetic fields. Detailed knowledge of the x-ray system installation is required to provide estimates of system operation.

  2. Endoscopic vs. tactile evaluation of subgingival calculus.

    PubMed

    Osborn, Joy B; Lenton, Patricia A; Lunos, Scott A; Blue, Christine M

    2014-08-01

    Endoscopic technology has been developed to facilitate imagery for use during diagnostic and therapeutic phases of periodontal care. The purpose of this study was to compare the level of subgingival calculus detection using a periodontal endoscope with that of conventional tactile explorer in periodontitis subjects. A convenience sample of 26 subjects with moderate periodontitis in at least 2 quadrants was recruited from the University of Minnesota School of Dentistry to undergo quadrant scaling and root planing. One quadrant from each subject was randomized for tactile calculus detection alone and the other quadrant for tactile detection plus the Perioscope ™ (Perioscopy Inc., Oakland, Cali). A calculus index on a 0 to 3 score was performed at baseline and at 2 post-scaling and root planing visits. Sites where calculus was detected at visit 1 were retreated. T-tests were used to determine within-subject differences between Perioscope™ and tactile measures, and changes in measures between visits. Significantly more calculus was detected using the Perioscope™ vs. tactile explorer for all 3 subject visits (p<0.005). Mean changes (reduction) in calculus detection from baseline to visit 1 were statistically significant for both the Perioscope™ and tactile quadrants (p<0.0001). However, further reductions in calculus detection from visit 1 to visit 2 was only significant for the Perioscope™ quadrant (p<0.025), indicating that this methodology was able to more precisely detect calculus at this visit. It was concluded that the addition of a visual component to calculus detection via the Perioscope™ was most helpful in the re-evaluation phase of periodontal therapy. Copyright © 2014 The American Dental Hygienists’ Association.

  3. Stochastic model for the 3D microstructure of pristine and cyclically aged cathodes in Li-ion batteries

    NASA Astrophysics Data System (ADS)

    Kuchler, Klaus; Westhoff, Daniel; Feinauer, Julian; Mitsch, Tim; Manke, Ingo; Schmidt, Volker

    2018-04-01

    It is well-known that the microstructure of electrodes in lithium-ion batteries strongly affects their performance. Vice versa, the microstructure can exhibit strong changes during the usage of the battery due to aging effects. For a better understanding of these effects, mathematical analysis and modeling has turned out to be of great help. In particular, stochastic 3D microstructure models have proven to be a powerful and very flexible tool to generate various kinds of particle-based structures. Recently, such models have been proposed for the microstructure of anodes in lithium-ion energy and power cells. In the present paper, we describe a stochastic modeling approach for the 3D microstructure of cathodes in a lithium-ion energy cell, which differs significantly from the one observed in anodes. The model for the cathode data enhances the ideas of the anode models, which have been developed so far. It is calibrated using 3D tomographic image data from pristine as well as two aged cathodes. A validation based on morphological image characteristics shows that the model is able to realistically describe both, the microstructure of pristine and aged cathodes. Thus, we conclude that the model is suitable to generate virtual, but realistic microstructures of lithium-ion cathodes.

  4. A position sensitive microchannel photomultiplier for ultraviolet space astronomy

    NASA Technical Reports Server (NTRS)

    Lampton, M.; Siegmund, O. H. W.; Bixler, J.; Bowyer, S.

    1986-01-01

    The 25-mm microchannel-plate, position-sensitive UV astronomy photomultiplier tube presented is intended for the EOM-1 Spacelab Mission's FAUST payload and conducts wide-field imaging surveys in the VUV over the 1400-1800-A range. The sealed detector encompasses a CsI photocathode deposited on the inner surface of a MgF2 window, a stack of microchannel plates, and a wedge-and-strip two-dimensional position-sensing anode. Since the wedge-and-strip principle requires only three anode signals, flight electronics can be reduced to three charge amplifiers and three analog-to-digital converters.

  5. Kinky thresholds revisited: opportunity costs differ in the NE and SW quadrants.

    PubMed

    Eckermann, Simon

    2015-02-01

    Historically, a kinked threshold line on the cost-effectiveness plane at the origin was suggested due to differences in willingness to pay (WTP) for health gain with trade-offs in the north-east (NE) quadrant versus willingness to accept (WTA) cost reductions for health loss with trade-offs in the south-west (SW) quadrant. Empirically, WTA is greater than WTP for equivalent units of health, a finding supported by loss aversion under prospect theory. More recently, appropriate threshold values for health effects have been shown to require an endogenous consideration of the opportunity cost of alternative actions in budget-constrained health systems, but also allocative and displacement inefficiency observed in health system practice. Allocative and displacement inefficiency arise in health systems where the least cost-effective program in contraction has a higher incremental cost-effectiveness ratio (ICER = m) than the most cost-effective program in expansion (ICER = n) and displaced services (ICER = d), respectively. The health shadow price derived by Pekarsky, [Formula: see text] reflects the opportunity cost of best alternative adoption and financing actions in reimbursing new technology with expected incremental costs and net effect allowing for allocative (n < m), and displacement, inefficiency (d < m). This provides an appropriate threshold value for the NE quadrant. In this paper, I show that for trade-offs in the SW quadrant, where new strategies have lower expected net cost while lower expected net effect than current practice, the opportunity cost is contraction of the least cost-effective program, with threshold ICER m. That is, in the SW quadrant, the cost reduction per unit of decreased effect should be compared with the appropriate opportunity cost, best alternative generation of funding. Consequently, appropriate consideration of opportunity cost produces a kink in the threshold at the origin, with the health shadow price in the NE quadrant and ICER of the least cost-effective program in contraction (m) in the SW quadrant having the same general shape as that previously suggested by WTP versus WTA. The extent of this kink depends on the degree of allocative and displacement inefficiency, with no kink in the threshold line strictly only appropriate with complete allocative and displacement efficiency, that is n = d = m.

  6. OBSERVATIONS OF THE CRAB NEBULA'S ASYMMETRICAL DEVELOPMENT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Loll, A. M.; Desch, S. J.; Scowen, P. A.

    2013-03-10

    We present the first Hubble Space Telescope Wide Field Planetary Camera-2 imaging survey of the entire Crab Nebula, in the filters F502N ([O III] emission), F673N ([S II]), F631N ([O I]), and F547M (continuum). We use our mosaics to characterize the pulsar wind nebula (PWN) and its three-dimensional structure, the ionizational structure in the filaments forming at its periphery, the speed of the shock driven by the PWN into surrounding ejecta (by inferring the cooling rates behind the shock), and the morphology and ionizational structure of the Rayleigh-Taylor (R-T) fingers. We quantify a number of asymmetries between the northwest (NW)more » and southeast (SE) quadrants of the Crab Nebula. The lack of observed filaments in the NW, and our observations of the spatial extent of [O III] emission lead us to conclude that cooling rates are slower, and therefore the shock speeds are greater, in the NW quadrant of the nebula, compared with the SE. We conclude that R-T fingers are longer, more ionizationally stratified, and apparently more massive in the NW than in the SE, and the R-T instability appears more fully developed in the NW.« less

  7. In vivo and in vitro hyperspectral imaging of cervical neoplasia

    NASA Astrophysics Data System (ADS)

    Wang, Chaojian; Zheng, Wenli; Bu, Yanggao; Chang, Shufang; Tong, Qingping; Zhang, Shiwu; Xu, Ronald X.

    2014-02-01

    Cervical cancer is a prevalent disease in many developing countries. Colposcopy is the most common approach for screening cervical intraepithelial neoplasia (CIN). However, its clinical efficacy heavily relies on the examiner's experience. Spectroscopy is a potentially effective method for noninvasive diagnosis of cervical neoplasia. In this paper, we introduce a hyperspectral imaging technique for noninvasive detection and quantitative analysis of cervical neoplasia. A hyperspectral camera is used to collect the reflectance images of the entire cervix under xenon lamp illumination, followed by standard colposcopy examination and cervical tissue biopsy at both normal and abnormal sites in different quadrants. The collected reflectance data are calibrated and the hyperspectral signals are extracted. Further spectral analysis and image processing works are carried out to classify tissue into different types based on the spectral characteristics at different stages of cervical intraepithelial neoplasia. The hyperspectral camera is also coupled with a lab microscope to acquire the hyperspectral transmittance images of the pathological slides. The in vivo and the in vitro imaging results are compared with clinical findings to assess the accuracy and efficacy of the method.

  8. Imaging spectrophotometry of ionized gas in NGC 1068. I - Kinematics of the narrow-line region

    NASA Technical Reports Server (NTRS)

    Cecil, Gerald; Bland, Jonathan; Tully, R. Brent

    1990-01-01

    The kinematics of collisionally excited forbidden N II 6548, 6583 across the inner 1 arcmin diameter of the nearby Seyfert galaxy NGC 1068 is mapped using an imaging Fabry-Perot interferometer and low-noise CCD. The stack of monochromatic images, which spatially resolved the high-velocity gas, was analyzed for kinematic and photometric content. Profiles agree well with previous long-slit work, and their complete spatial coverage makes it possible to constrain the gas volume distribution. It is found that the narrow-line region is distributed in a thick center-darkened, line-emitting cylinder that envelopes the collimated radio jet. Three distinct kinematic subsystems, of which the cylinder is composed, are discussed in detail. Detailed behavior of the emission-line profiles, at the few points in the NE quadrant with simple kinematics, argues that the ionized gas develops a significant component of motion perpendicular to the jet axis.

  9. The Evolution of Solid Oxide Fuel Cell Nickel-Yttria Stabilized Zirconia Anodes Studied Using Electrochemical and Three-Dimensional Microstructural Characterizations

    NASA Astrophysics Data System (ADS)

    Kennouche, David O.

    This thesis focuses on Solid Oxide Fuel Cells (SOFCs). The 21st century will see major changes in the way energy is produced, stored, and used around the world. SOFCs, which provide an efficient, scalable, and low-pollution alternative method for electricity generation, are expected to play an important role. SOFCs can also be operated in electrolysis mode for energy storage, important since health and economic reasons are causing a shift towards intermittent renewable energy resources. However, multiple limitations mainly linked to cost and durability have prevented the expansion of this technology to mass markets. This work focuses on the Nickel - Yttria Stabilized Zirconia (Ni-YSZ) anode that is widely used in SOFCs. Coarsening of Ni in the Ni-YSZ anode has been widely cited as a primary cause of long-term SOFC degradation. While there have been numerous studies of Ni coarsening reported, these have typically only tracked the evolution of Ni particle size, not the entire microstructure, and have typically not been correlated directly with electrochemical performance. In this thesis, the advanced tomography techniques Focused Ion Beam - Scanning Electron Microscopy (FIB-SEM) tomography and Trans- mission X-ray Microscopy (TXM) have been utilized to enable insight into the evolution of Ni-YSZ structure and how it relates to performance degradation. Extensive anode aging studies were done for relatively short times using temperatures higher than in normal SOFC operation in order to accelerate microstructural evolution. In addition the microstructure changes were correlated with changes in anode polarization resistance. While most of the measurements were done by comparing different anodes aged under different conditions, the first example of a "pseudo in situ" measurement where the same anode was 3D imaged repeatedly with intervening aging steps, was also demonstrated. A microstructural evolution model that focuses on the active three-phase boundary density was fitted to the experimental data, and subsequently used to predict the change in anode three-phase boundary density and average particle size for extended times under normal SOFC conditions. Characterization of other anodes (pulsed-laser deposited and micro-tubular geometries) produced by international collaborators is also presented. Finally, a testing setup and protocol for anode life testing with current density and overpotential has been developed and implemented. Early test results are presented.

  10. Self-assessing target with automatic feedback

    DOEpatents

    Larkin, Stephen W.; Kramer, Robert L.

    2004-03-02

    A self assessing target with four quadrants and a method of use thereof. Each quadrant containing possible causes for why shots are going into that particular quadrant rather than the center mass of the target. Each possible cause is followed by a solution intended to help the marksman correct the problem causing the marksman to shoot in that particular area. In addition, the self assessing target contains possible causes for general shooting errors and solutions to the causes of the general shooting error. The automatic feedback with instant suggestions and corrections enables the shooter to improve their marksmanship.

  11. Investigation of several aspects of LANDSAT-4 data quality. [Sacramento, San Francisco, and NE Arkansas

    NASA Technical Reports Server (NTRS)

    Wrigley, R. C. (Principal Investigator)

    1984-01-01

    The Thematic Mapper scene of Sacramento, CA acquired during the TDRSS test was received in TIPS format. Quadrants for both scenes were tested for band-to-band registration using reimplemented block correlation techniques. Summary statistics for band-to-band registrations of TM band combinations for Quadrant 4 of the NE Arkansas scene in TIPS format are tabulated as well as those for Quadrant 1 of the Sacramento scene. The system MTF analysis for the San Francisco scene is completed. The thermal band did not have sufficient contrast for the targets used and was not analyzed.

  12. Nuclear Graphite - Fracture Behavior and Modeling

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Burchell, Timothy D; Battiste, Rick; Strizak, Joe P

    2011-01-01

    Evidence for the graphite fracture mechanism is reviewed and discussed. The roles of certain microstructural features in the graphite fracture process are reported. The Burchell fracture model is described and its derivation reported. The successful application of the fracture model to uniaxial tensile data from several graphites with widely ranging structure and texture is reported. The extension of the model to multiaxial loading scenarios using two criteria is discussed. Initially, multiaxial strength data for H-451 graphite were modeled using the fracture model and the Principle of Independent Action. The predicted 4th stress quadrant failure envelope was satisfactory but the 1stmore » quadrant predictions were not conservative and thus were unsatisfactory. Multiaxial strength data from the 1st and 4th stress quadrant for NBG-18 graphite are reported. To improve the conservatism of the predicted 1st quadrant failure envelope for NBG-18 the Shetty criterion has been applied to obtain the equivalent critical stress intensity factor, KIc (Equi), for each applied biaxial stress ratio. The equivalent KIc value is used in the Burchell fracture model to predict the failure envelope. The predicted 1st stress quadrant failure envelope is conservative and thus more satisfactory than achieved previously using the fracture model combined with the Principle of Independent Action.« less

  13. A systematic review of posture and psychosocial factors as contributors to upper quadrant musculoskeletal pain in children and adolescents.

    PubMed

    Prins, Yolandi; Crous, Lynette; Louw, Q A

    2008-01-01

    Musculoskeletal pain has become a major symptomatic complaint among children and adolescents and is increasingly occurring at a younger age. This systematic review was done to evaluate the evidence for the contribution of posture and psychosocial factors to the development of upper quadrant musculoskeletal pain in children and adolescents. The review describes the measurement tools used to assess musculoskeletal pain, sitting posture, and psychosocial factors. Two independent reviewers searched seven databases for observational studies that included prospective and cross-sectional study designs. Ten studies were extracted and assessed by two reviewers using the Critical Appraisal Form-Quantitative Studies (Law et al, 1998). The studies measured upper quadrant musculoskeletal pain as an outcome measure. Five studies evaluated sitting posture and found an association between the duration of static sitting and upper quadrant musculoskeletal pain. Six studies measured psychosocial factors of which depression, stress, and psychosomatic symptoms were the factors most commonly found to influence the development of upper quadrant musculoskeletal pain. The eligible studies used different pain measurement tools and different measurement tools to assess sitting posture and psychosocial factors. This review concludes that the duration of sitting posture and psychosocial factors may influence the experience of musculoskeletal pain among children and adolescents.

  14. Genesis Silicon Carbide Concentrator Target 60003 Preliminary Ellipsometry Mapping Results

    NASA Technical Reports Server (NTRS)

    Calaway, M. J.; Rodriquez, M. C.; Stansbery, E. K.

    2007-01-01

    The Genesis concentrator was custom designed to focus solar wind ions primarily for terrestrial isotopic analysis of O-17/O-16 and O-18/O-16 to +/-1%, N-15/N-14 to +/-1%, and secondarily to conduct elemental and isotopic analysis of Li, Be, and B. The circular 6.2 cm diameter concentrator target holder was comprised of four quadrants of highly pure semiconductor materials that included one amorphous diamond-like carbon, one C-13 diamond, and two silicon carbide (SiC). The amorphous diamond-like carbon quadrant was fractured upon impact at Utah Test and Training Range (UTTR), but the remaining three quadrants survived fully intact and all four quadrants hold an important collection of solar wind. The quadrants were removed from the target holder at NASA Johnso n Space Center Genesis Curation Laboratory in April 2005, and have been housed in stainless steel containers under continual nitrogen purge since time of disintegration. In preparation for allocation of a silicon carbide target for oxygen isotope analyses at UCLA, the two SiC targets were photographed for preliminary inspection of macro particle contamination from the hard non-nominal landing as well as characterized by spectroscopic ellipsometry to evaluate thin film contamination. This report is focused on Genesis SiC target sample number 60003.

  15. Full Robotic Colorectal Resections for Cancer Combined With Other Major Surgical Procedures: Early Experience With the da Vinci Xi.

    PubMed

    Morelli, Luca; Di Franco, Gregorio; Guadagni, Simone; Palmeri, Matteo; Gianardi, Desirée; Bianchini, Matteo; Moglia, Andrea; Ferrari, Vincenzo; Caprili, Giovanni; D'Isidoro, Cristiano; Melfi, Franca; Di Candio, Giulio; Mosca, Franco

    2017-08-01

    The da Vinci Xi has been developed to overcome some of the limitations of the previous platform, thereby increasing the acceptance of its use in robotic multiorgan surgery. Between January 2015 and October 2015, 10 patients with synchronous tumors of the colorectum and others abdominal organs underwent robotic combined resections with the da Vinci Xi. Trocar positions respected the Universal Port Placement Guidelines provided by Intuitive Surgical for "left lower quadrant," with trocars centered on the umbilical area, or shifted 2 to 3 cm to the right or to the left, depending on the type of combined surgical procedure. All procedures were completed with the full robotic technique. Simultaneous procedures in same quadrant or left quadrant and pelvis, or left/right and upper, were performed with a single docking/single targeting approach; in cases of left/right quadrant or right quadrant/pelvis, we performed a dual-targeting operation. No external collisions or problems related to trocar positions were noted. No patient experienced postoperative surgical complications and the mean hospital stay was 6 days. The high success rate of full robotic colorectal resection combined with other surgical interventions for synchronous tumors, suggest the efficacy of the da Vinci Xi in this setting.

  16. High precision dual-axis tracking solar wireless charging system based on the four quadrant photoelectric sensor

    NASA Astrophysics Data System (ADS)

    Liu, Zhilong; Wang, Biao; Tong, Weichao

    2015-08-01

    This paper designs a solar automatic tracking wireless charging system based on the four quadrant photoelectric sensor. The system track the sun's rays automatically in real time to received the maximum energy and wireless charging to the load through electromagnetic coupling. Four quadrant photoelectric sensor responsive to the solar spectrum, the system could get the current azimuth and elevation angle of the light by calculating the solar energy incident on the sensor profile. System driver the solar panels by the biaxial movement mechanism to rotate and tilt movement until the battery plate and light perpendicular to each other. Maximize the use of solar energy, and does not require external power supply to achieve energy self-sufficiency. Solar energy can be collected for portable devices and load wireless charging by close electromagnetic field coupling. Experimental data show that: Four quadrant photoelectric sensor more sensitive to light angle measurement. when track positioning solar light, Azimuth deviation is less than 0.8°, Elevation angle deviation is less than 0.6°. Use efficiency of a conventional solar cell is only 10% -20%.The system uses a Four quadrant dual-axis tracking to raise the utilization rate of 25% -35%.Wireless charging electromagnetic coupling efficiency reached 60%.

  17. Retinal oxygen saturation in Chinese adolescents.

    PubMed

    Liu, Xue; Wang, Shuang; Liu, Yi; Liu, Li Juan; Lv, Yan Yun; Tang, Ping; Jonas, Jost B; Xu, Liang

    2017-02-01

    To study the retinal oxygen saturation in normal eyes of Chinese adolescents. Performing retinal oximetry with the Oxymap T1 Retinal Oximeter in healthy children and adolescents (aged 5-18 years old), we measured the arterial (SaO 2 ) and venular (SvO 2 ) oxygen saturation and the arteriovenous difference in oxygen saturation (Sa-vO 2 ). The study included 122 individuals with a mean age of 13.0 ± 2.9 years (range: 5-18 years) and a mean refractive error of -3.25 ± 2.49 dioptres (range:-8.88 to +3.13 dioptres). Mean SaO 2 , SvO 2 and Sa-vO 2 was 85.5 ± 7.1%, 48.2 ± 5.5% and 37.3 ± 6.5%, respectively. Mean SaO 2 was significantly (p < 0.001) the lowest in the inferotemporal quadrant (79.1 ± 9.0%), followed by the superotemporal quadrant (83.4 ± 9.7%), the inferonasal quadrant (90.4 ± 10.6%) and the superonasal quadrant (93.4 ± 10.8%). In a similar manner, the values of the SvO 2 were the lowest (p < 0.001) in the inferotemporal quadrant (42.1 ± 8.3%), followed by the superotemporal quadrant (47.8 ± 7.2%), the inferonasal quadrant (52.3 ± 8.4%) and the superonasal quadrant (55.1 ± 7.6%). Arteriovenous difference in oxygen saturation (Sa-vO 2 ) did not differ significantly (all p > 0.05) between the fundus quadrants. In multiple linear regression analysis, SaO 2 increased (regression coefficient r 2  = 0.28) with older age (standardized regression coefficient β: 0.23; p = 0.01) and more myopic refractive error (β: -0.39; p < 0.001). Higher SvO 2 was significantly correlated with more myopic refractive error (β: -0.46; p < 0.001; r 2  = 0.20), while Sa-vO 2 increased significantly only with older age in the multivariate analysis (β: 0.26; p = 0.01; r 2  = 0.07). Our study provides normative data for Chinese children and adolescents who showed lower values than adults for SaO 2 and SvO 2 . SaO 2 increased with older age and higher myopic refractive error, SvO 2 increased with higher myopic refractive error, and Sa-vO 2 increased with older age. © 2016 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

  18. 3D Microstructure Effects in Ni-YSZ Anodes: Prediction of Effective Transport Properties and Optimization of Redox Stability

    PubMed Central

    Pecho, Omar M.; Stenzel, Ole; Iwanschitz, Boris; Gasser, Philippe; Neumann, Matthias; Schmidt, Volker; Prestat, Michel; Hocker, Thomas; Flatt, Robert J.; Holzer, Lorenz

    2015-01-01

    This study investigates the influence of microstructure on the effective ionic and electrical conductivities of Ni-YSZ (yttria-stabilized zirconia) anodes. Fine, medium, and coarse microstructures are exposed to redox cycling at 950 °C. FIB (focused ion beam)-tomography and image analysis are used to quantify the effective (connected) volume fraction (Φeff), constriction factor (β), and tortuosity (τ). The effective conductivity (σeff) is described as the product of intrinsic conductivity (σ0) and the so-called microstructure-factor (M): σeff = σ0 × M. Two different methods are used to evaluate the M-factor: (1) by prediction using a recently established relationship, Mpred = εβ0.36/τ5.17, and (2) by numerical simulation that provides conductivity, from which the simulated M-factor can be deduced (Msim). Both methods give complementary and consistent information about the effective transport properties and the redox degradation mechanism. The initial microstructure has a strong influence on effective conductivities and their degradation. Finer anodes have higher initial conductivities but undergo more intensive Ni coarsening. Coarser anodes have a more stable Ni phase but exhibit lower YSZ stability due to lower sintering activity. Consequently, in order to improve redox stability, it is proposed to use mixtures of fine and coarse powders in different proportions for functional anode and current collector layers. PMID:28793523

  19. In situ fluorescence imaging of localized corrosion with a pH-sensitive imaging fiber

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Panova, A.A.; Pantano, P.; Walt, D.R.

    1997-12-01

    A fiber optic pH-sensor capable of both visualizing corrosion sites and measuring local chemical concentrations is applied to real-time corrosion monitoring. The imaging fiber`s distal face containing an immobilized pH-sensitive fluorescent dye is brought into contact with metal surfaces submerged in aqueous buffers and fluorescence images are acquired as a function of time. The observed changes in fluorescence due to increases in pH at cathodic sites and decreases in pH at anodic sites are indicative of localized corrosion rates.

  20. A reconfigurable image tube using an external electronic image readout

    NASA Astrophysics Data System (ADS)

    Lapington, J. S.; Howorth, J. R.; Milnes, J. S.

    2005-08-01

    We have designed and built a sealed tube microchannel plate (MCP) intensifier for optical/NUV photon counting applications suitable for 18, 25 and 40 mm diameter formats. The intensifier uses an electronic image readout to provide direct conversion of event position into electronic signals, without the drawbacks associated with phosphor screens and subsequent optical detection. The Image Charge technique is used to remove the readout from the intensifier vacuum enclosure, obviating the requirement for additional electrical vacuum feedthroughs and for the readout pattern to be UHV compatible. The charge signal from an MCP intensifier is capacitively coupled via a thin dielectric vacuum window to the electronic image readout, which is external to the sealed intensifier tube. The readout pattern is a separate item held in proximity to the dielectric window and can be easily detached, making the system easily reconfigurable. Since the readout pattern detects induced charge and is external to the tube, it can be constructed as a multilayer, eliminating the requirement for narrow insulator gaps and allowing it to be constructed using standard PCB manufacturing tolerances. We describe two readout patterns, the tetra wedge anode (TWA), an optimized 4 electrode device similar to the wedge and strip anode (WSA) but with a factor 2 improvement in resolution, and an 8 channel high speed 50 ohm device, both manufactured as multilayer PCBs. We present results of the detector imaging performance, image resolution, linearity and stability, and discuss the development of an integrated readout and electronics device based on these designs.

  1. Advanced morphological analysis of patterns of thin anodic porous alumina

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Toccafondi, C.; Istituto Italiano di Tecnologia, Department of Nanostructures, Via Morego 30, Genova I 16163; Stępniowski, W.J.

    2014-08-15

    Different conditions of fabrication of thin anodic porous alumina on glass substrates have been explored, obtaining two sets of samples with varying pore density and porosity, respectively. The patterns of pores have been imaged by high resolution scanning electron microscopy and analyzed by innovative methods. The regularity ratio has been extracted from radial profiles of the fast Fourier transforms of the images. Additionally, the Minkowski measures have been calculated. It was first observed that the regularity ratio averaged across all directions is properly corrected by the coefficient previously determined in the literature. Furthermore, the angularly averaged regularity ratio for themore » thin porous alumina made during short single-step anodizations is lower than that of hexagonal patterns of pores as for thick porous alumina from aluminum electropolishing and two-step anodization. Therefore, the regularity ratio represents a reliable measure of pattern order. At the same time, the lower angular spread of the regularity ratio shows that disordered porous alumina is more isotropic. Within each set, when changing either pore density or porosity, both regularity and isotropy remain rather constant, showing consistent fabrication quality of the experimental patterns. Minor deviations are tentatively discussed with the aid of the Minkowski measures, and the slight decrease in both regularity and isotropy for the final data-points of the porosity set is ascribed to excess pore opening and consequent pore merging. - Highlights: • Thin porous alumina is partly self-ordered and pattern analysis is required. • Regularity ratio is often misused: we fix the averaging and consider its spread. • We also apply the mathematical tool of Minkowski measures, new in this field. • Regularity ratio shows pattern isotropy and Minkowski helps in assessment. • General agreement with perfect artificial patterns confirms the good manufacturing.« less

  2. Build-It-Yourself Astronomy.

    ERIC Educational Resources Information Center

    Lamb, William G.

    1983-01-01

    Instructions for constructing cross staffs and quadrants are provided. Astronomy teaching methods using the two devices are discussed. These include locating common constellations with the cross staff and following a star (or moon, sun, or planets) by reading the altitude and azimuth with the quadrant. (JN)

  3. Spatiotemporal Patterns of Tumor Occurrence in Children with Intraocular Retinoblastoma.

    PubMed

    King, Benjamin A; Parra, Carlos; Li, Yimei; Helton, Kathleen J; Qaddoumi, Ibrahim; Wilson, Matthew W; Ogg, Robert J

    2015-01-01

    To accurately map the retinal area covered by tumor in a prospectively enrolled cohort of children diagnosed with retinoblastoma. Orbital MRI in 106 consecutive retinoblastoma patients (44 bilateral) was analyzed. For MRI-visible tumors, the polar angle and angle of eccentricity of points defining tumor perimeter on the retina were determined by triangulation from images in three orthogonal planes. The centroid of the mapped area was calculated to approximate tumor origin, and the location and cumulative tumor burden were analyzed in relation to mutation type (germline vs. somatic), tumor area, and patient age at diagnosis. Location of small tumors undetected by MRI was approximated with fundoscopic images. Mapping was successful for 129 tumors in 91 eyes from 67 patients (39 bilateral, 43 germline mutation). Cumulative tumor burden was highest within the macula and posterior pole and was asymmetrically higher within the inferonasal periphery. Tumor incidence was lowest in the superotemporal periphery. Tumor location varied with age at diagnosis in a complex pattern. Tumor location was concentrated in the macula and superonasal periphery in patients <5.6 months, in the inferotemporal quadrant of the posterior pole in patients 5.6-8.8 months, in the inferonasal quadrant in patients 8.8-13.2 months, and in the nasal and superotemporal periphery in patients >13.2 months. The distribution of MRI-invisible tumors was consistent with the asymmetry of mapped tumors. MRI-based mapping revealed a previously unrecognized pattern of retinoblastoma localization that evolves with age at diagnosis. The structured spatiotemporal distribution of tumors may provide valuable clues about cellular or molecular events associated with tumorigenesis in the developing retina.

  4. Comparing Gonioscopy With Visante and Cirrus Optical Coherence Tomography for Anterior Chamber Angle Assessment in Glaucoma Patients.

    PubMed

    Hu, Cindy X; Mantravadi, Anand; Zangalli, Camila; Ali, Mohsin; Faria, Bruno M; Richman, Jesse; Wizov, Sheryl S; Razeghinejad, M Reza; Moster, Marlene R; Katz, L Jay

    2016-02-01

    The aim of this study was to compare gonioscopy with Visante and Cirrus optical coherence tomography (OCT) for identifying angle structures and the presence of angle closure in patients with glaucoma. A secondary objective was to assess interrater agreement for gonioscopy grading among 3 independent examiners. Gonioscopy grading using Spaeth Classification and determination of angle-closure risk was performed on 1 randomly selected eye for 50 phakic patients. Images of the same eye using both Visante and Cirrus OCT were obtained in both light and dark conditions. Agreement of angle closure among 3 devices and interrater agreement for gonioscopy were determined using Cohen's κ (K) or Kendall's coefficient of concordance (W). Of the 50 patients, 60% were female, 64% were white, and the mean age was 62 years. Angle closure was detected in 18%, 16%, and 48% of quadrants with Visante, Cirrus, and gonioscopy, respectively. The scleral spur was identified in 56% and 50% of quadrants with Visante and Cirrus OCT, respectively. Visante and Cirrus OCT showed moderate agreement in detecting angle closure (K=0.42 light, K=0.53 dark) but slight-to-fair agreement with gonioscopy (Visante K=0.25, Cirrus K=0.15). Gonioscopy demonstrated substantial agreement in angle closure (K=0.65 to 0.68) and angle-closure risk assessment (W=0.83) among 3 examiners. Visante and Cirrus OCT imaging may have limited ability to identify angle closure because of difficulty identifying angle structures. Gonioscopy by well-trained clinicians had remarkably consistent agreement for identifying angle-closure risk.

  5. Individual A-Scan Signal Normalization Between Two Spectral Domain Optical Coherence Tomography Devices

    PubMed Central

    Chen, Chieh-Li; Ishikawa, Hiroshi; Wollstein, Gadi; Ling, Yun; Bilonick, Richard A.; Kagemann, Larry; Sigal, Ian A.; Schuman, Joel S.

    2013-01-01

    Purpose. We developed a method to normalize optical coherence tomography (OCT) signal profiles from two spectral-domain (SD) OCT devices so that the comparability between devices increases. Methods. We scanned 21 eyes from 14 healthy and 7 glaucoma subjects with two SD-OCT devices on the same day, with equivalent cube scan patterns centered on the fovea (Cirrus HD-OCT and RTVue). Foveola positions were selected manually and used as the center for registration of the corresponding images. A-scan signals were sampled 1.8 mm from the foveola in the temporal, superior, nasal, and inferior quadrants. After oversampling and rescaling RTVue data along the Z-axis to match the corresponding Cirrus data format, speckle noise reduction and amplitude normalization were applied. For comparison between normalized A-scan profiles, mean absolute difference in amplitude in percentage was measured at each sampling point. As a reference, the mean absolute difference between two Cirrus scans on the same eye also was measured. Results. The mean residual of the A-scan profile amplitude was reduced significantly after signal normalization (12.7% vs. 6.2%, P < 0.0001, paired t-test). All four quadrants also showed statistically significant reduction (all P < 0.0001). Mean absolute difference after normalization was smaller than the one between two Cirrus scans. No performance difference was detected between health and glaucomatous eyes. Conclusions. The reported signal normalization method successfully reduced the A-scan profile differences between two SD-OCT devices. This signal normalization processing may improve the direct comparability of OCT image analysis and measurement on various devices. PMID:23611992

  6. A Simple and Reliable Technique to Orient Donor Corneal Tissue Using the Radial Width of the Surgical Limbus.

    PubMed

    Aldrich, Benjamin T; Stockman, Adam M; Freiburger, Monica J; Shinkunas, Todd J; Burckart, Kimberlee A; Schmidt, Gregory A; Reed, Cynthia R; Zimmerman, M Bridget; Goins, Kenneth M; Wagoner, Michael D; Greiner, Mark A

    2015-12-01

    To develop a method based on identification of the widest region of the surgical limbus that can yield quick and accurate orientation of excised human donor corneas. Corneoscleral tissue from donors 49 to 75 years old was marked at the temporal sclera at the time of recovery. Digital images obtained from 20 corneas stored in viewing chambers, retroilluminated and viewed from the endothelial side, were used to quantify the per-degree radial width of the surgical limbus, defined as the distance from the scleral spur to clear cornea. To evaluate differences in radial width among regions, measurements were compared with the intracorneal mean limbal width, and a per-degree z-score was calculated by averaging among corneas. Using images of corneas with the temporal mark masked and the sidedness known, 6 observers were subjected to a blinded trial of 10 corneas to determine the central point of the widest limbal region of each cornea. Compared with the intracorneal mean, the mean radial width of the surgical limbus was greatest in the superior quadrant, and the difference compared with the inferior, nasal, and temporal quadrants was significant (P < 0.0001). The superior region was identified with 100% accuracy in blinded trials. The average absolute difference between the predicted and actual central point of the superior limbus was 9.75 ± 0.30 degrees. The radial width of the surgical limbus is greatest in the superior region of the cornea and can be used as a diagnostic feature to orient donor corneal tissue.

  7. Diagnostic Capability of Peripapillary Retinal Thickness in Glaucoma Using 3D Volume Scans

    PubMed Central

    Simavli, Huseyin; Que, Christian John; Akduman, Mustafa; Rizzo, Jennifer L.; Tsikata, Edem; de Boer, Johannes F.; Chen, Teresa C.

    2015-01-01

    Purpose To determine the diagnostic capability of spectral domain optical coherence tomography (SD-OCT) peripapillary retinal thickness (RT) measurements from 3-dimensional (3D) volume scans for primary open angle glaucoma (POAG). Design Cross-sectional study. Methods Setting Institutional Study population 156 patients (89 POAG and 67 normal subjects) Observation procedures One eye of each subject was included. SD-OCT peripapillary RT values from 3D volume scans were calculated for four quadrants of three different sized annuli. Peripapillary retinal nerve fiber layer (RNFL) thickness values were also determined. Main outcome measures Area under the receiver operating characteristic curve (AUROC) values, sensitivity, specificity, positive and negative predictive values, and positive and negative likelihood ratios. Results The top five RT AUROCs for all glaucoma patients and for a subset of early glaucoma patients were for the inferior quadrant of outer circumpapillary annulus of circular grid (OCA) 1 (0.959, 0.939), inferior quadrant of OCA2 (0.945, 0.921), superior quadrant of OCA1 (0.890, 0.811), inferior quadrant of OCA3 (0.887, 0.854), and superior quadrant of OCA2 (0.879, 0.807). Smaller RT annuli OCA1 and OCA2 consistently showed better diagnostic performance than the larger RT annulus OCA3. For both RNFL and RT measurements, best AUROC values were found for inferior RT OCA1 and OCA2, followed by inferior and overall RNFL thickness. Conclusion Peripapillary RT measurements from 3D volume scans showed excellent diagnostic performance for detecting both glaucoma and early glaucoma patients. Peripapillary RT values have the same or better diagnostic capability compared to peripapillary RNFL thickness measurements, while also having fewer algorithm errors. PMID:25498354

  8. Role of "diseased" root cementum in healing following treatment of periodontal disease. A clinical study.

    PubMed

    Nyman, S; Westfelt, E; Sarhed, G; Karring, T

    1988-08-01

    This clinical trial was undertaken to examine whether root debridement in the treatment of periodontal disease must include the removal of the exposed cementum in order to achieve periodontal health. The study included 11 adult patients with moderate to advanced periodontal disease. In a split-mouth design, the dentition of each patient was by random selection divided into test- and control quadrants comprising the incisors, canines and premolars. Following a baseline examination, all patients were given a case presentation and a detailed instruction in self-performed oral hygiene measures. The patients were then subjected to periodontal surgery. Following reverse bevel incisions, buccal and lingual mucoperiosteal flaps were elevated and all granulation tissue was removed. In 2 jaw quadrants (control quadrants) in each patient, the denuded root surfaces were carefully scaled and planed in order to remove soft and hard deposits as well as all cementum, using hand instruments and flame-formed diamond stones. In the contralateral quadrants (test quadrants) the roots were not scaled and planed but soft microbial deposits were removed by polishing the root surfaces with the but soft microbial deposits were removed by polishing the root surfaces with the use of rubber cups, interdental rubber tips and a polishing paste. Calculus in the test quadrants was removed by the use of a curette, but precaution was taken to avoid the removal of cementum. The flaps were repositioned to their original level and sutured. The patients were following active treatment enrolled in a supervised maintenance care program including "professional tooth cleaning" once every 2 weeks for a 3-month period.(ABSTRACT TRUNCATED AT 250 WORDS)

  9. One-year clinical results of Er,Cr:YSGG laser application in addition to scaling and root planing in patients with early to moderate periodontitis.

    PubMed

    Kelbauskiene, Solveiga; Baseviciene, Nomeda; Goharkhay, Kawe; Moritz, Andreas; Machiulskiene, Vita

    2011-07-01

    In 30 patients with periodontitis, a total of 278 teeth exhibiting bleeding on probing, subgingival calculus, and a probing depth between 3-6 mm were examined. For each participant, two treatment types were alternatively applied on the contralateral quadrants: scaling and root planing (SRP) as control, and SRP followed by Er,Cr:YSGG laser application (SRP+laser), as a test method. Five clinical parameters: plaque level, bleeding on probing, probing depth, gingival recession and clinical attachment level were examined at baseline and at 2, 3, 6, 12 months after treatment. Of the total of 1,668 sites examined in all patients, 1,088 sites were found with a probing depth of 3-6 mm. In these sites, differences in clinical parameters between SRP and SRP+laser-treated quadrants were analyzed, assuming the level of p < 0.05 as significant. After 2 months from baseline, the mean probing depth reduction and the clinical attachment level gain were significantly greater in SRP+laser than in SRP quadrants, and remained so throughout the study (p < 0.001). A marked reduction of the bleeding scores occurred in all examined sites, irrespective of the treatment method. However, after 12 months, significantly less teeth exhibited bleeding on probing in SRP+laser quadrants than in SRP quadrants (p < 0.001). The mean plaque and gingival recession levels did not differ between the SRP and SRP+laser quadrants neither before nor after the treatment. The periodontal procedures either using Er,Cr:YSGG laser after SRP or SRP alone, lead to significant improvements in all clinical parameters investigated. However, laser application, as an adjunct to SRP, appeared to be more advantageous.

  10. Tumour location within the breast: Does tumour site have prognostic ability?

    PubMed

    Rummel, Seth; Hueman, Matthew T; Costantino, Nick; Shriver, Craig D; Ellsworth, Rachel E

    2015-01-01

    Tumour location within the breast varies with the highest frequency in the upper outer quadrant (UOQ) and lowest frequency in the lower inner quadrant (LIQ). Whether tumour location is prognostic is unclear. To determine whether tumour location is prognostic, associations between tumour site and clinicopathological characteristics were evaluated. All patients enrolled in the Clinical Breast Care Project whose tumour site-UOQ, upper inner quadrant (UIQ), central, LIQ, lower outer quadrant (LOQ)-was determined by a single, dedicated breast pathologist were included in this study. Patients with multicentric disease (n = 122) or tumours spanning multiple quadrants (n = 381) were excluded from further analysis. Clinicopathological characteristics were analysed using chi-square tests for univariate analysis with multivariate analysis performed using principal components analysis (PCA) and multiple logistic regression. Significance was defined as P < 0.05. Of the 980 patients with defined tumour location, 30 had bilateral disease. Tumour location in the UOQ (51.5%) was significantly higher than in the UIQ (15.6%), LOQ (14.2%), central (10.6%), or LIQ (8.1%). Tumours in the central quadrant were significantly more likely to have higher tumour stage (P = 0.003) and size (P < 0.001), metastatic lymph nodes (P < 0.001), and mortality (P = 0.011). After multivariate analysis, only tumour size and lymph node status remained significantly associated with survival. Evaluation of tumour location as a prognostic factor revealed that although tumours in the central region are associated with less favourable outcome, these associations are not independent of location but rather driven by larger tumour size. Tumours in the central region are more difficult to detect mammographically, resulting in larger tumour size at diagnosis and thus less favourable prognosis. Together, these data demonstrate that tumour location is not an independent prognostic factor.

  11. Liquid metal anode x-ray tubes: interesting, but are they useful?

    NASA Astrophysics Data System (ADS)

    Harding, Geoffrey

    2004-10-01

    An analysis is presented of factors affecting the specific loadability (W mm-2 K-1) of electron impact liquid metal anode x-ray sources (LIMAX). It is shown that in general, the limit to loadability is set by energy deposited in the electron window by inelastic electron scattering. Removal of this energy through convection cooling by the liquid metal stream represents the least efficient thermal transport process in LIMAX. As the electron window energy loss is approximately inversely proportional to the electron beam energy, the power loadability of a LIMAX source operated under otherwise constant conditions scales roughly with the square of the tube voltage. A comparison of the loadability of the liquid metal anode x-ray concept to conventional stationary anode x-ray tubes demonstrates the superiority of the former. The utility of LIMAX-based computed tomography in the field of air cargo container inspection is briefly discussed. In particular its characteristics relative to linac-based air cargo container inspection are highlighted: these include a higher contrast-to-noise ratio (CNR); compact radiation shielding and collimation; reduced detector cross-talk; improved image contrast; and the possibility of combining container CT with material-specific alarm resolution capability based on x-ray diffraction tomography.

  12. Structure for implementation of back-illuminated CMOS or CCD imagers

    NASA Technical Reports Server (NTRS)

    Pain, Bedabrata (Inventor); Cunningham, Thomas J. (Inventor)

    2009-01-01

    A structure for implementation of back-illuminated CMOS or CCD imagers. An epitaxial silicon layer is connected with a passivation layer, acting as a junction anode. The epitaxial silicon layer converts light passing through the passivation layer and collected by the imaging structure to photoelectrons. A semiconductor well is also provided, located opposite the passivation layer with respect to the epitaxial silicon layer, acting as a junction cathode. Prior to detection, light does not pass through a dielectric separating interconnection metal layers.

  13. Impact de la preparation des anodes crues et des conditions de cuisson sur la fissuration dans des anodes denses

    NASA Astrophysics Data System (ADS)

    Amrani, Salah

    La fabrication de l'aluminium est realisee dans une cellule d'electrolyse, et cette operation utilise des anodes en carbone. L'evaluation de la qualite de ces anodes reste indispensable avant leur utilisation. La presence des fissures dans les anodes provoque une perturbation du procede l'electrolyse et une diminution de sa performance. Ce projet a ete entrepris pour determiner l'impact des differents parametres de procedes de fabrication des anodes sur la fissuration des anodes denses. Ces parametres incluent ceux de la fabrication des anodes crues, des proprietes des matieres premieres et de la cuisson. Une recherche bibliographique a ete effectuee sur tous les aspects de la fissuration des anodes en carbone pour compiler les travaux anterieurs. Une methodologie detaillee a ete mise au point pour faciliter le deroulement des travaux et atteindre les objectifs vises. La majorite de ce document est reservee pour la discussion des resultats obtenus au laboratoire de l'UQAC et au niveau industriel. Concernant les etudes realisees a l'UQAC, une partie des travaux experimentaux est reservee a la recherche des differents mecanismes de fissuration dans les anodes denses utilisees dans l'industrie d'aluminium. L'approche etait d'abord basee sur la caracterisation qualitative du mecanisme de la fissuration en surface et en profondeur. Puis, une caracterisation quantitative a ete realisee pour la determination de la distribution de la largeur de la fissure sur toute sa longueur, ainsi que le pourcentage de sa surface par rapport a la surface totale de l'echantillon. Cette etude a ete realisee par le biais de la technique d'analyse d'image utilisee pour caracteriser la fissuration d'un echantillon d'anode cuite. L'analyse surfacique et en profondeur de cet echantillon a permis de voir clairement la formation des fissures sur une grande partie de la surface analysee. L'autre partie des travaux est basee sur la caracterisation des defauts dans des echantillons d'anodes crues fabriquees industriellement. Cette technique a consiste a determiner le profil des differentes proprietes physiques. En effet, la methode basee sur la mesure de la distribution de la resistivite electrique sur la totalite de l'echantillon est la technique qui a ete utilisee pour localiser la fissuration et les macro-pores. La microscopie optique et l'analyse d'image ont, quant a elles, permis de caracteriser les zones fissurees tout en determinant la structure des echantillons analyses a l'echelle microscopique. D'autres tests ont ete menes, et ils ont consiste a etudier des echantillons cylindriques d'anodes de 50 mm de diametre et de 130 mm de longueur. Ces derniers ont ete cuits dans un four a UQAC a differents taux de chauffage dans le but de pouvoir determiner l'influence des parametres de cuisson sur la formation de la fissuration dans ce genre de carottes. La caracterisation des echantillons d'anodes cuites a ete faite a l'aide de la microscopie electronique a balayage et de l'ultrason. La derniere partie des travaux realises a l'UQAC contient une etude sur la caracterisation des anodes fabriquees au laboratoire sous differentes conditions d'operation. L'evolution de la qualite de ces anodes a ete faite par l'utilisation de plusieurs techniques. L'evolution de la temperature de refroidissement des anodes crues de laboratoire a ete mesuree; et un modele mathematique a ete developpe et valide avec les donnees experimentales. Cela a pour objectif d'estimer la vitesse de refroidissement ainsi que le stress thermique. Toutes les anodes fabriquees ont ete caracterisees avant la cuisson par la determination de certaines proprietes physiques (resistivite electrique, densite apparente, densite optique et pourcentage de defauts). La tomographie et la distribution de la resistivite electrique, qui sont des techniques non destructives, ont ete employees pour evaluer les defauts internes des anodes. Pendant la cuisson des anodes de laboratoire, l'evolution de la resistivite electrique a ete suivie et l'etape de devolatilisation a ete identifiee. Certaines anodes ont ete cuites a differents taux de chauffage (bas, moyen, eleve et un autre combine) dans l'objectif de trouver les meilleures conditions de cuisson en vue de minimiser la fissuration. D'autres anodes ont ete cuites a differents niveaux de cuisson, cela dans le but d'identifier a quelle etape de l'operation de cuisson la fissuration commence a se developper. Apres la cuisson, les anodes ont ete recuperees pour, a nouveau, faire leur caracterisation par les memes techniques utilisees precedemment. L'objectif principal de cette partie etait de reveler l'impact de differents parametres sur le probleme de fissuration, qui sont repartis sur toute la chaine de production des anodes. Le pourcentage de megots, la quantite de brai et la distribution des particules sont des facteurs importants a considerer pour etudier l'effet de la matiere premiere sur le probleme de la fissuration. Concernant l'effet des parametres du procede de fabrication sur le meme probleme, le temps de vibration, la pression de compaction et le procede de refroidissement ont ete a la base de cette etude. Finalement, l'influence de la phase de cuisson sur l'apparition de la fissuration a ete prise en consideration par l'intermediaire du taux de chauffage et du niveau de cuisson. Les travaux realises au niveau industriel ont ete faits lors d'une campagne de mesure dans le but d'evaluer la qualite des anodes de carbone en general et l'investigation du probleme de fissuration en particulier. Ensuite, il s'agissait de reveler les effets de differents parametres sur le probleme de la fissuration. Vingt-quatre anodes cuites ont ete utilisees. Elles ont ete fabriquees avec differentes matieres premieres (brai, coke, megots) et sous diverses conditions (pression, temps de vibration). Le parametre de la densite de fissuration a ete calcule en se basant sur l'inspection visuelle de la fissuration des carottes. Cela permet de classifier les differentes fissurations en plusieurs categories en se basant sur certains criteres tels que le type de fissures (horizontale, verticale et inclinee), leurs localisations longitudinales (bas, milieu et haut de l'anode) et transversales (gauche, centrale et droite). Les effets de la matiere premiere, les parametres de fabrication des anodes crues ainsi que les conditions de cuisson sur la fissuration ont ete etudies. La fissuration des anodes denses en carbones cause un serieux probleme pour l'industrie d'aluminium primaire. La realisation de ce projet a permis la revelation de differents mecanismes de fissuration, la classification de fissuration par plusieurs criteres (position, types localisation) et l'evaluation de l'impact de differents parametres sur la fissuration. Les etudes effectuees dans le domaine de cuisson ont donne la possibilite d'ameliorer l'operation et reduire la fissuration des anodes. Le travail consiste aussi a identifier des techniques capables d'evaluer la qualite d'anodes (l'ultrason, la tomographie et la distribution de la resistivite electrique). La fissuration des anodes en carbone est consideree comme un probleme complexe, car son apparition depend de plusieurs parametres repartis sur toute la chaine de production. Dans ce projet, plusieurs nouvelles etudes ont ete realisees, et elles permettent de donner de l'originalite aux travaux de recherches faits dans le domaine de la fissuration des anodes de carbone pour l'industrie de l'aluminium primaire. Les etudes realisees dans ce projet permettent d'ajouter d'un cote, une valeur scientifique pour mieux comprendre le probleme de fissuration des anodes et d'un autre cote, d'essayer de proposer des methodes qui peuvent reduire ce probleme a l'echelle industrielle.

  14. A Population-Based Assessment of the Agreement Between Grading of Goniophotographic Images and Gonioscopy in the Chinese-American Eye Study (CHES)

    PubMed Central

    Murakami, Yohko; Wang, Dandan; Burkemper, Bruce; Lin, Shan C.; Varma, Rohit

    2016-01-01

    Purpose To compare grading of goniophotographic images and gonioscopy in assessing the iridocorneal angle. Methods In a population-based, cross-sectional study, participants underwent gonioscopy and goniophotographic imaging during the same visit. The iridocorneal angle was classified as closed if the posterior trabecular meshwork could not be seen. A single masked observer graded the goniophotographic images, and each eye was classified as having angle closure based on the number of closed quadrants. Agreement between the methods was analyzed by calculating kappa (κ) and first-order agreement coefficient (AC1) statistics and comparison of area under receiver operating characteristic curves (AUC). Results A total of 4149 Chinese Americans (3994 eyes) were included in this study. The agreement for angle closure diagnosis between gonioscopy and EyeCam was moderate to excellent (κ = 0.60, AC1 0.90, AUC 0.76–0.80). Conclusions Detection of iridocorneal angle closure based on goniophotographic imaging shows moderate to very good agreement with angle closure assessment using gonioscopy. PMID:27571018

  15. A radar vehicle detection system for four-quadrant gate warning systems and blocked crossing detection.

    DOT National Transportation Integrated Search

    2012-12-01

    The Wavetronix Matrix Radar was adapted for use at four-quadrant gate railroad crossings for the purpose of influencing exit gate behavior upon the detection of vehicles, as an alternative to buried inductive loops. Two radar devices were utilized, o...

  16. Spatial distribution of parasitism on Phyllocnistis citrella Stainton, 1856 (Lepidoptera: Gracillariidae) in citrus orchards.

    PubMed

    Jahnke, S M; Redaelli, L R; Diefenbach, L M G; Efrom, C F

    2008-11-01

    Many species of microhymenopterous parasitoids have been registered on Phyllocnistis citrella, the citrus leafminer. The present study aimed to identify the spatial distribution pattern of the native and introduced parasitoids of P. citrella in two citrus orchards in Montenegro, RS. The new shoots from 24 randomly selected trees in each orchard were inspected at the bottom (0-1.5 m) and top (1.5-2.5 m) stratum and had their position relative to the quadrants (North, South, East and West) registered at every 15 days from July/2002 to June/2003. The leaves with pupae were collected and kept isolated until the emergence of parasitoids or of the leaf miner; so, the sampling was biased towards parasitoids that emerge in the host pupal phase. The horizontal spatial distribution was evaluated testing the fitness of data to the Poisson and negative binomial distributions. In Montenegrina, there was no significant difference in the number of parasitoids and in the mean number of pupae found in the top and bottom strata (chi2 = 0.66; df = 1; P > 0.05) (chi2 = 0.27; df =1; P > 0.05), respectively. In relation to the quadrants, the highest average numbers of the leafminer pupae and of parasitoids were registered at the East quadrant (chi2 = 11.81; df = 3; P < 0.05), (chi2 = 10.36; df = 3; P < 0.05). In the Murcott orchard, a higher number of parasitoids was found at the top stratum (63.5%) (chi2 = 7.24; df =1 P < 0.05), the same occurring with the average number of P. citrella pupae (62.9%) (chi2 = 6.66; df = 1; P < 0.05). The highest number of parasitoids and of miners was registered at the North quadrant (chi2 = 19. 29; df = 3; P < 0.05), (chi2 = 4.39; df = 3; P < 0.05). In both orchards, there was no difference between the numbers of shoots either relative to the strata as well as to the quadrants. As the number of shoots did not varied much relative to the quadrants, it is possible that the higher number of miners and parasitoids in the East and West quadrants would be influenced by the higher solar exposure of these quadrants. The data of the horizontal spatial distribution of the parasitism fit to the negative binomial distribution in all sampling occasions, indicating an aggregated pattern.

  17. X-ray emission from high temperature plasmas

    NASA Technical Reports Server (NTRS)

    Harries, W. L.

    1974-01-01

    X-rays from a 25-hJ plasma focus apparatus were observed with pinhole cameras. The cameras consist of 0.4 mm diameter pinholes in 2 cm thick lead housing enclosing an X-ray intensifying screen at the image plane. Pictures recorded through thin aluminum foils or plastic sheets for X-ray energies sub gamma smaller than 15 keV show distributed X-ray emissions from the focussed plasma and from the anode surface. However, when thick absorbers are used, radial filamentary structure in the X-ray emission from the anode surface is revealed. Occasionally larger structures are observed in addition to the filaments. Possible mechanisms for the filamentary structure are discussed.

  18. Where Does the Transplanted Fat is Located in the Gluteal Region? Research Letter.

    PubMed

    Ramos-Gallardo, Guillermo; Medina-Zamora, Pablo; Cardenas-Camarena, Lázaro; Orozco-Rentería, David; Duran-Vega, Héctor; Mota-Fonseca, Eduardo

    2017-12-29

    Liposuction is one of the most popular plastic surgery procedures. As in any surgery, there are risks and complications, especially when combined with fat injection. Case reports of fat embolism have been reported. A possible explanation is the puncture and tearing of gluteal vessels during the procedure, especially when a deep injection is planned. To identify the places where fat can be located after injection during a fat graft in the gluteus. An experimental study was done in which colorant was injected in four directions using four different quadrants of the gluteus. We Injected 10 cc six times following clock hands until 60 cc were injected, and the cutaneous flap and the muscles were then elevated. Our main purpose was to describe where the colorant went and if it was in contact with the vessels (superior and inferior gluteal vessels). In total, four gluteus muscles were injected and dissected. Injection in the lower lateral quadrant was mainly into the muscle, and colorant was observed in the hypogastric vessels. The injection in the upper quadrants stayed mainly in the subcutaneous tissue. During surgery, it is important to identify the location of the perforators and to avoid a deep injection, especially from the lower lateral quadrant to the superior medial quadrant (Q4 to Q1), as the probability of puncturing and injecting fat into the main vessels from this direction is higher.

  19. Loneliness and Hypervigilance to Social Cues in Females: An Eye-Tracking Study

    PubMed Central

    Lodder, Gerine M. A.; Scholte, Ron H. J.; Clemens, Ivar A. H.; Engels, Rutger C. M. E.; Goossens, Luc; Verhagen, Maaike

    2015-01-01

    The goal of the present study was to examine whether lonely individuals differ from nonlonely individuals in their overt visual attention to social cues. Previous studies showed that loneliness was related to biased post-attentive processing of social cues (e.g., negative interpretation bias), but research on whether lonely and nonlonely individuals also show differences in an earlier information processing stage (gazing behavior) is very limited. A sample of 25 lonely and 25 nonlonely students took part in an eye-tracking study consisting of four tasks. We measured gazing (duration, number of fixations and first fixation) at the eyes, nose and mouth region of faces expressing emotions (Task 1), at emotion quadrants (anger, fear, happiness and neutral expression) (Task 2), at quadrants with positive and negative social and nonsocial images (Task 3), and at the facial area of actors in video clips with positive and negative content (Task 4). In general, participants tended to gaze most often and longest at areas that conveyed most social information, such as the eye region of the face (T1), and social images (T3). Participants gazed most often and longest at happy faces (T2) in still images, and more often and longer at the facial area in negative than in positive video clips (T4). No differences occurred between lonely and nonlonely participants in their gazing times and frequencies, nor at first fixations at social cues in the four different tasks. Based on this study, we found no evidence that overt visual attention to social cues differs between lonely and nonlonely individuals. This implies that biases in social information processing of lonely individuals may be limited to other phases of social information processing. Alternatively, biased overt attention to social cues may only occur under specific conditions, for specific stimuli or for specific lonely individuals. PMID:25915656

  20. In Situ Chemical Imaging of Solid-Electrolyte Interphase Layer Evolution in Li–S Batteries

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nandasiri, Manjula I.; Camacho-Forero, Luis E.; Schwarz, Ashleigh M.

    Parasitic reactions of electrolyte and polysulfide with the Li-anode in lithium sulfur (Li-S) batteries lead to the formation of solid-electrolyte interphase (SEI) layers, which are the major reason behind severe capacity fading in these systems. Despite numerous studies, the evolution mechanism of the SEI layer and specific roles of polysulfides and other electrolyte components are still unclear. Here, we report an in-situ X-ray photoelectron spectroscopy (XPS) and chemical imaging analysis combined with ab initio molecular dynamics (AIMD) computational modeling to gain fundamental understanding regarding the evolution of SEI layers on Li-anodes within Li-S batteries. A multi-modal approach involving AIMD modelingmore » and in-situ XPS characterization uniquely reveals the chemical identity and distribution of active participants in parasitic reactions as well as the SEI layer evolution mechanism. The SEI layer evolution has three major stages: the formation of a primary composite mixture phase involving stable lithium compounds (Li 2S, LiF, Li 2O etc); and formation of a secondary matrix type phase due to cross interaction between reaction products and electrolyte components, which is followed by a highly dynamic mono-anionic polysulfide (i.e. LiS 5) fouling process. In conclusion, these new molecular-level insights into the SEI layer evolution on Li- anodes are crucial for delineating effective strategies for the development of Li–S batteries.« less

  1. In Situ Chemical Imaging of Solid-Electrolyte Interphase Layer Evolution in Li–S Batteries

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nandasiri, Manjula I.; Camacho-Forero, Luis E.; Schwarz, Ashleigh M.

    Parasitic reactions of electrolyte and polysulfide with the Li-anode in lithium sulfur (Li-S) batteries lead to the for-mation of solid electrolyte interphase (SEI) layers, which are the major reason behind severe capacity fading in these systems. Despite numerous studies, the evolution mechanism of the SEI layer and specific roles of polysulfides and oth-er electrolyte components are still unclear. We report an in-situ X-ray photoelectron spectroscopy (XPS) and chemical imaging analysis combined with ab initio molecular dynamics (AIMD) computational modeling to gain fundamental understanding regarding the evolution of SEI layers on Li-anodes within Li-S batteries. A multi-modal approach in-volving AIMD modelingmore » and in-situ XPS characterization uniquely reveals the chemical identity and distribution of active participants in parasitic reactions as well as the SEI layer evolution mechanism. The SEI layer evolution has three major stages: the formation of a primary composite mixture phase involving stable lithium compounds (Li2S, LiF, Li2O etc); and formation of a secondary matrix type phase due to cross interaction between reaction products and elec-trolyte components, which is followed by a highly dynamic mono-anionic polysulfide (i.e. LiS5) fouling process. These new molecular-level insights into the SEI layer evolution on Li- anodes are crucial for delineating effective strategies for the development of Li–S batteries.« less

  2. In Situ Chemical Imaging of Solid-Electrolyte Interphase Layer Evolution in Li–S Batteries

    DOE PAGES

    Nandasiri, Manjula I.; Camacho-Forero, Luis E.; Schwarz, Ashleigh M.; ...

    2017-05-03

    Parasitic reactions of electrolyte and polysulfide with the Li-anode in lithium sulfur (Li-S) batteries lead to the formation of solid-electrolyte interphase (SEI) layers, which are the major reason behind severe capacity fading in these systems. Despite numerous studies, the evolution mechanism of the SEI layer and specific roles of polysulfides and other electrolyte components are still unclear. Here, we report an in-situ X-ray photoelectron spectroscopy (XPS) and chemical imaging analysis combined with ab initio molecular dynamics (AIMD) computational modeling to gain fundamental understanding regarding the evolution of SEI layers on Li-anodes within Li-S batteries. A multi-modal approach involving AIMD modelingmore » and in-situ XPS characterization uniquely reveals the chemical identity and distribution of active participants in parasitic reactions as well as the SEI layer evolution mechanism. The SEI layer evolution has three major stages: the formation of a primary composite mixture phase involving stable lithium compounds (Li 2S, LiF, Li 2O etc); and formation of a secondary matrix type phase due to cross interaction between reaction products and electrolyte components, which is followed by a highly dynamic mono-anionic polysulfide (i.e. LiS 5) fouling process. In conclusion, these new molecular-level insights into the SEI layer evolution on Li- anodes are crucial for delineating effective strategies for the development of Li–S batteries.« less

  3. Cultural-Historical Activity Theory/Design-Based Research in Pasteur's Quadrant

    ERIC Educational Resources Information Center

    Greeno, James G.

    2016-01-01

    About two decades ago, Donald Stokes published "Pasteur's Quadrant" (Stokes, 1997). Stokes proposed that the motivations of different research projects can be understood as a two-dimensional system, with higher or lower concern for improving technology and practice on one dimension and higher or lower concern for improving fundamental…

  4. 49 CFR 230.89 - Reverse gear.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Reverse gear. 230.89 Section 230.89 Transportation... Reversing Gear § 230.89 Reverse gear. (a) General provisions. Reverse gear, reverse levers, and quadrants... quadrant. Proper counterbalance shall be provided for the valve gear. (b) Air-operated power reverse gear...

  5. Theoretical model and experimental investigation of current density boundary condition for welding arc study

    NASA Astrophysics Data System (ADS)

    Boutaghane, A.; Bouhadef, K.; Valensi, F.; Pellerin, S.; Benkedda, Y.

    2011-04-01

    This paper presents results of theoretical and experimental investigation of the welding arc in Gas Tungsten Arc Welding (GTAW) and Gas Metal Arc Welding (GMAW) processes. A theoretical model consisting in simultaneous resolution of the set of conservation equations for mass, momentum, energy and current, Ohm's law and Maxwell equation is used to predict temperatures and current density distribution in argon welding arcs. A current density profile had to be assumed over the surface of the cathode as a boundary condition in order to make the theoretical calculations possible. In stationary GTAW process, this assumption leads to fair agreement with experimental results reported in literature with maximum arc temperatures of ~21 000 K. In contrast to the GTAW process, in GMAW process, the electrode is consumable and non-thermionic, and a realistic boundary condition of the current density is lacking. For establishing this crucial boundary condition which is the current density in the anode melting electrode, an original method is setup to enable the current density to be determined experimentally. High-speed camera (3000 images/s) is used to get geometrical dimensions of the welding wire used as anode. The total area of the melting anode covered by the arc plasma being determined, the current density at the anode surface can be calculated. For a 330 A arc, the current density at the melting anode surface is found to be of 5 × 107 A m-2 for a 1.2 mm diameter welding electrode.

  6. Photon-Counting H33D Detector for Biological Fluorescence Imaging

    PubMed Central

    Michalet, X.; Siegmund, O.H.W.; Vallerga, J.V.; Jelinsky, P.; Millaud, J.E.; Weiss, S.

    2010-01-01

    We have developed a photon-counting High-temporal and High-spatial resolution, High-throughput 3-Dimensional detector (H33D) for biological imaging of fluorescent samples. The design is based on a 25 mm diameter S20 photocathode followed by a 3-microchannel plate stack, and a cross delay line anode. We describe the bench performance of the H33D detector, as well as preliminary imaging results obtained with fluorescent beads, quantum dots and live cells and discuss applications of future generation detectors for single-molecule imaging and high-throughput study of biomolecular interactions. PMID:20151021

  7. Intensity distribution of the x ray source for the AXAF VETA-I mirror test

    NASA Technical Reports Server (NTRS)

    Zhao, Ping; Kellogg, Edwin M.; Schwartz, Daniel A.; Shao, Yibo; Fulton, M. Ann

    1992-01-01

    The X-ray generator for the AXAF VETA-I mirror test is an electron impact X-ray source with various anode materials. The source sizes of different anodes and their intensity distributions were measured with a pinhole camera before the VETA-I test. The pinhole camera consists of a 30 micrometers diameter pinhole for imaging the source and a Microchannel Plate Imaging Detector with 25 micrometers FWHM spatial resolution for detecting and recording the image. The camera has a magnification factor of 8.79, which enables measuring the detailed spatial structure of the source. The spot size, the intensity distribution, and the flux level of each source were measured with different operating parameters. During the VETA-I test, microscope pictures were taken for each used anode immediately after it was brought out of the source chamber. The source sizes and the intensity distribution structures are clearly shown in the pictures. They are compared and agree with the results from the pinhole camera measurements. This paper presents the results of the above measurements. The results show that under operating conditions characteristic of the VETA-I test, all the source sizes have a FWHM of less than 0.45 mm. For a source of this size at 528 meters away, the angular size to VETA is less than 0.17 arcsec which is small compared to the on ground VETA angular resolution (0.5 arcsec, required and 0.22 arcsec, measured). Even so, the results show the intensity distributions of the sources have complicated structures. These results were crucial for the VETA data analysis and for obtaining the on ground and predicted in orbit VETA Point Response Function.

  8. Quantification of breast density with dual energy mammography: A simulation study

    PubMed Central

    Ducote, Justin L.; Molloi, Sabee

    2008-01-01

    Breast density, the percentage of glandular breast tissue, has been identified as an important yet underutilized risk factor in the development of breast cancer. A quantitative method to measure breast density with dual energy imaging was investigated using a computer simulation model. Two configurations to measure breast density were evaluated: the usage of monoenergetic beams and an ideal detector, and the usage of polyenergetic beams with spectra from a tungsten anode x-ray tube with a detector modeled after a digital mammography system. The simulation model calculated the mean glandular dose necessary to quantify the variability of breast density to within 1∕3%. The breast was modeled as a semicircle 10 cm in radius with equal homogenous thicknesses of adipose and glandular tissues. Breast thicknesses were considered in the range of 2–10 cm and energies in the range of 10–150 keV for the two monoenergetic beams, and 20–150 kVp for spectra with a tungsten anode x-ray tube. For a 4.2 cm breast thickness, the required mean glandular doses were 0.183 μGy for two monoenergetic beams at 19 and 71 keV, and 9.85 μGy for two polyenergetic spectra from a tungsten anode at 32 and 96 kVp with beam filtrations of 50 μm Rh and 300 μm Cu for the low and high energy beams, respectively. The results suggest that for either configuration, breast density can be precisely measured with dual energy imaging requiring only a small amount of additional dose to the breast. The possibility of using a standard screening mammogram as the low energy image is also discussed. PMID:19175100

  9. Particulate inverse opal carbon electrodes for lithium-ion batteries.

    PubMed

    Kang, Da-Young; Kim, Sang-Ok; Chae, Yu Jin; Lee, Joong Kee; Moon, Jun Hyuk

    2013-01-29

    Inverse opal carbon materials were used as anodes for lithium ion batteries. We applied particulate inverse opal structures and their dispersion in the formation of anode electrodes via solution casting. We prepared aminophenyl-grafted inverse opal carbons (a-IOC), inverse opal carbons with mesopores (mIOC), and bare inverse opal carbons (IOC) and investigated the electrochemical behavior of these samples as anode materials. Surface modification by aminophenyl groups was confirmed by XPS measurements. TEM images showed mesopores, and the specific area of mIOC was compared with that of IOC using BET analysis. A half-cell test was performed to compare a-IOC with IOC and mIOC with IOC. In the case of the a-IOC structure, the cell test revealed no improvement in the reversible specific capacity or the cycle performance. The mIOC cell showed a reversible specific capacity of 432 mAh/g, and the capacity was maintained at 88%-approximately 380 mAh/g-over 20 cycles.

  10. Facile design of ultra-thin anodic aluminum oxide membranes for the fabrication of plasmonic nanoarrays.

    PubMed

    Hao, Qi; Huang, Hao; Fan, Xingce; Hou, Xiangyu; Yin, Yin; Li, Wan; Si, Lifang; Nan, Haiyan; Wang, Huaiyu; Mei, Yongfeng; Qiu, Teng; Chu, Paul K

    2017-03-10

    Ultra-thin anodic aluminum oxide (AAO) membranes are efficient templates for the fabrication of patterned nanostructures. Herein, a three-step etching method to control the morphology of AAO is described. The morphological evolution of the AAO during phosphoric acid etching is systematically investigated and a nonlinear growth mechanism during unsteady-state anodization is revealed. The thickness of the AAO can be quantitatively controlled from ∼100 nm to several micrometers while maintaining the tunablity of the pore diameter. The AAO membranes are robust and readily transferable to different types of substrates to prepare patterned plasmonic nanoarrays such as nanoislands, nanoclusters, ultra-small nanodots, and core-satellite superstructures. The localized surface plasmon resonance from these nanostructures can be easily tuned by adjusting the morphology of the AAO template. The custom AAO template provides a platform for the fabrication of low-cost and large-scale functional nanoarrays suitable for fundamental studies as well as applications including biochemical sensing, imaging, photocatalysis, and photovoltaics.

  11. Facile design of ultra-thin anodic aluminum oxide membranes for the fabrication of plasmonic nanoarrays

    NASA Astrophysics Data System (ADS)

    Hao, Qi; Huang, Hao; Fan, Xingce; Hou, Xiangyu; Yin, Yin; Li, Wan; Si, Lifang; Nan, Haiyan; Wang, Huaiyu; Mei, Yongfeng; Qiu, Teng; Chu, Paul K.

    2017-03-01

    Ultra-thin anodic aluminum oxide (AAO) membranes are efficient templates for the fabrication of patterned nanostructures. Herein, a three-step etching method to control the morphology of AAO is described. The morphological evolution of the AAO during phosphoric acid etching is systematically investigated and a nonlinear growth mechanism during unsteady-state anodization is revealed. The thickness of the AAO can be quantitatively controlled from ˜100 nm to several micrometers while maintaining the tunablity of the pore diameter. The AAO membranes are robust and readily transferable to different types of substrates to prepare patterned plasmonic nanoarrays such as nanoislands, nanoclusters, ultra-small nanodots, and core-satellite superstructures. The localized surface plasmon resonance from these nanostructures can be easily tuned by adjusting the morphology of the AAO template. The custom AAO template provides a platform for the fabrication of low-cost and large-scale functional nanoarrays suitable for fundamental studies as well as applications including biochemical sensing, imaging, photocatalysis, and photovoltaics.

  12. Quantification of the methane concentration using anaerobic oxidation of methane coupled to extracellular electron transfer.

    PubMed

    Gao, Yaohuan; Ryu, Hodon; Rittmann, Bruce E; Hussain, Abid; Lee, Hyung-Sool

    2017-10-01

    A biofilm anode acclimated with growth media containing acetate, then acetate+methane, and finally methane alone produced electrical current in a microbial electrochemical cell (MxC) fed with methane as the sole electron donor. Geobacter was the dominant genus for the bacterial domain (93%) in the biofilm anode, while methanogens (Methanocorpusculum labreanum and Methanosaeta concilii) accounted for 82% of the total archaeal clones in the biofilm. Fluorescence in situ hybridization (FISH) imaging clearly showed a biofilm of mixed bacteria and archaea, suggesting a syntrophic interaction between them for performing anaerobic oxidation of methane (AOM) in the biofilm anode. Measured cumulative coulombs were linearly correlated to the methane-gas concentration in the range of 10-99.97% (R 2 ≥0.99) when the measurement was sustained for at least 50min Thus, cumulative coulombs over 50min could be used to quantify the methane concentration in gas samples. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. Porous Fe2O3 Microspheres as Anode for Lithium-Ion Batteries

    NASA Astrophysics Data System (ADS)

    Noerochim, L.; Indra, M. A. T.; Purwaningsih, H.; Subhan, A.

    2018-05-01

    In this work, Fe2O3 was successfully synthesized by the hydrothermal process at low temperature. FeCl3.6H2O as precursor and variation of lysine as hydrolyzing agent were used to preparing Fe2O3. SEM images show that the morphology of Fe2O3 is porous microsphere with sizes in the range of (1 to 5) µm in diameter. The as-prepared Fe2O3 with the 2 M of lysine exhibits excellent cycling performance when used as the anode for lithium ion batteries, obtaining reversible discharge capacity of 172.33 mA·h·g‑1 at 0.5 C after 50 cycles. It is attributed to the unique structure of porous microspheres providing a large surface area which maintains good electronic contact between particles during charge-discharge process. This result demonstrates that Fe2O3 porous microsphere has a high potential as anode material for application of lithium-ion battery.

  14. Understanding the crack formation of graphite particles in cycled commercial lithium-ion batteries by focused ion beam - scanning electron microscopy

    NASA Astrophysics Data System (ADS)

    Lin, Na; Jia, Zhe; Wang, Zhihui; Zhao, Hui; Ai, Guo; Song, Xiangyun; Bai, Ying; Battaglia, Vincent; Sun, Chengdong; Qiao, Juan; Wu, Kai; Liu, Gao

    2017-10-01

    The structure degradation of commercial Lithium-ion battery (LIB) graphite anodes with different cycling numbers and charge rates was investigated by focused ion beam (FIB) and scanning electron microscopy (SEM). The cross-section image of graphite anode by FIB milling shows that cracks, resulted in the volume expansion of graphite electrode during long-term cycling, were formed in parallel with the current collector. The crack occurs in the bulk of graphite particles near the lithium insertion surface, which might derive from the stress induced during lithiation and de-lithiation cycles. Subsequently, crack takes place along grain boundaries of the polycrystalline graphite, but only in the direction parallel with the current collector. Furthermore, fast charge graphite electrodes are more prone to form cracks since the tensile strength of graphite is more likely to be surpassed at higher charge rates. Therefore, for LIBs long-term or high charge rate applications, the tensile strength of graphite anode should be taken into account.

  15. In situ Scanning Electron Microscopy of Silicon Anode Reactions in Lithium-Ion Batteries during Charge/Discharge Processes

    PubMed Central

    Chen, Chih-Yao; Sano, Teruki; Tsuda, Tetsuya; Ui, Koichi; Oshima, Yoshifumi; Yamagata, Masaki; Ishikawa, Masashi; Haruta, Masakazu; Doi, Takayuki; Inaba, Minoru; Kuwabata, Susumu

    2016-01-01

    A comprehensive understanding of the charge/discharge behaviour of high-capacity anode active materials, e.g., Si and Li, is essential for the design and development of next-generation high-performance Li-based batteries. Here, we demonstrate the in situ scanning electron microscopy (in situ SEM) of Si anodes in a configuration analogous to actual lithium-ion batteries (LIBs) with an ionic liquid (IL) that is expected to be a functional LIB electrolyte in the future. We discovered that variations in the morphology of Si active materials during charge/discharge processes is strongly dependent on their size and shape. Even the diffusion of atomic Li into Si materials can be visualized using a back-scattering electron imaging technique. The electrode reactions were successfully recorded as video clips. This in situ SEM technique can simultaneously provide useful data on, for example, morphological variations and elemental distributions, as well as electrochemical data. PMID:27782200

  16. Chairside multi-unit restoration of a quadrant using the new Cerec 3D software.

    PubMed

    Ender, A; Wiedhahn, K; Mörmann, W H

    2003-01-01

    The new Cerec 3D design software for inlays and partial and full crowns simplifies work when producing several restorations in one session. Quite significant progress has been achieved, in that the entire row of teeth of a quadrant can be acquired completely and displayed by successively overlapping optical impressions. The digital working model of a quadrant in which all preparations are acquired is the result. The restorations can be designed individually and inserted virtually. Thanks to virtual insertion, the proximal contacts to neighboring restorations can be designed perfectly and all restorations finally designed, milled, and inserted in one sitting. This method provides a significant rationalization effect.

  17. The "four quadrants" approach to clinical ethics case analysis; an application and review.

    PubMed

    Sokol, D K

    2008-07-01

    In 1982, Jonsen, Siegler and Winslade published Clinical Ethics, in which they described the "four quadrants" approach, a new method of analysing clinical ethics cases. Although the book is now in its 6th edition, a literature search has revealed only one academic paper demonstrating the method at work. This paper is an attempt to start filling this gap. As a way of describing and testing the approach, I apply the four quadrants method to a detailed clinical ethics case. The analysis is interspersed with reflections on the method itself. It is hoped that this experiment will encourage ethicists and clinicians to devote more attention to this neglected approach.

  18. Performance of a static-anode/flat-panel x-ray fluoroscopy system in a diagnostic strength magnetic field: A truly hybrid x-ray/MR imaging system

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fahrig, R.; Wen, Z.; Ganguly, A.

    2005-06-15

    Minimally invasive procedures are increasing in variety and frequency, facilitated by advances in imaging technology. Our hybrid imaging system (GE Apollo{sup TM} flat panel, custom Brand x-ray static anode x-ray tube, GE Lunar high-frequency power supply and 0.5 T Signa SP{sup TM}) provides both x-ray and MR imaging capability to guide complex procedures without requiring motion of the patient between two distant gantries. The performance of the x-ray tube in this closely integrated system was evaluated by modeling and measuring both the response of the filament to an externally applied field and the behavior of the electron beam for fieldmore » strengths and geometries of interest. The performance of the detector was assessed by measuring the slanted-edge modulation transfer function (MTF) and when placed at zero field and at 0.5 T. Measured resonant frequencies of filaments can be approximated using a modified vibrating beam model, and were at frequencies well below the 25 kHz frequency of our generator for our filament geometry. The amplitude of vibration was not sufficient to cause shorting of the filament during operation within the magnetic field. A simple model of electrons in uniform electric and magnetic fields can be used to estimate the deflection of the electron beam on the anode for the fields of interest between 0.2 and 0.5 T. The MTF measured at the detector and the DQE showed no significant difference inside and outside of the magnetic field. With the proper modifications, an x-ray system can be fully integrated with a MR system, with minimal loss of image quality. Any x-ray tube can be assessed for compatibility when placed at a particular location within the field using the models. We have also concluded that a-Si electronics are robust against magnetic fields. Detailed knowledge of the x-ray system installation is required to provide estimates of system operation.« less

  19. Surgical management of an infected aggressive florid cemento-osseous dysplasia. Report of a case.

    PubMed

    Martini, M Zillo; de Carvalho Júnior, J Pereira; Soares, H Arid

    2006-09-01

    Florid cemento-osseous dysplasia (FCOD) is a quite rare condition presenting in the jaws and is most seen in middle-aged black women, from the 4th decade of life on. The pathogenesis of the cemento-osseous dysplasias remains unknown; however, they seem to represent some kind of reactional or dysplastic process. We describe an aggressive case of infected florid cemento-osseous dysplasia (IFCOD) in a 47-year-old black woman. Extensive dysplastic lesions affected all jaw quadrants and radiographic features showed images of irregular radiopaque multilobular masses, peripherally lined by a radiolucent layer. We decided to keep the patient in the hospital in order to perform endovenous medication, hydration, drainage and general care. The surgery planning would be started as soon as regression of the acute feature was observed. Histopathologic analysis revealed the lesion was composed by osseous and cementoid tissues, being its diagnosis compatible with FCOD. The surgical procedure was accomplished with the patient under general anesthesia. It was opted for the excision of the lesion in all quadrants, with sequestrectomy and total dental extraction and remodelling of the alveolar ridges. After 9 months of follow-up the patient is still undergoing clinical control, presenting healing within the expected patterns. Symptomatic cases follow-up should be lasting and periodical, since there are reports of recurrence.

  20. Homage to Bob Brodkey at 85: ejections, sweeps and the genesis and extensions of quadrant analysis

    NASA Astrophysics Data System (ADS)

    Wallace, James

    2013-11-01

    Almost 50 years ago Bob Brodkey and his student, Corino, conceived and carried out a visualization experiment for the very near wall region of a turbulent pipe flow (JFM 37) that, together with the turbulent boundary layer visualization of Kline et al. (JFM 30), excited the turbulence community. Using a high speed movie camera mounted on a lathe bed that recorded magnified images in a moving frame of reference, they observed the motions of small particles in the sub- and buffer-layers. Surprisingly, these motion were not nearly so locally random as was the general view of turbulence at the time. Rather, connected regions of the near wall flow decelerated and then erupted away from the wall in what they called ``ejections.'' These decelerated motions were followed by larger scale connected motions toward the wall from above that they called ``sweeps.'' Brodkey and Corino estimated that ejections accounted for 70 % the Reynolds shear stress at Red = 20 , 000 while only occurring about 18 % of the time. Wallace et al. (JFM 54) attempted to quantify these visual observations by conceiving of and carrying out a quadrant analyisis in a turbulent oil channel flow. This paper will trace this history and describe the expanding use of these ideas in turbulence research today.

  1. Varix of the vortex vein ampulla simulating choroidal melanoma: report of four cases.

    PubMed

    Gündüz, K; Shields, C L; Shields, J A

    1998-01-01

    Varix of the vortex vein ampulla is a condition that can cause diagnostic confusion with choroidal melanoma. A case series review was performed from the Ocular Oncology Service, Wills Eye Hospital. In all four cases, the patients were referred with the diagnosis of a small choroidal melanoma. The lesions were located in the nasal quadrant of the fundus near the equator. One patient had two lesions in the same quadrant. In all cases, the fundus lesion became more prominent when the eye gazed in the direction of the lesion and diminished in primary gaze. The mass measured up to 6.0 mm in base diameter and 2.5 mm in thickness in proper gaze. B-scan ultrasonography showed acoustic solidity and gaze-evoked dynamic enlargement of the lesion. Indocyanine green angiography demonstrated early pooling of dye and gaze-evoked fluctuation of the hyperfluorescence in the lesion. Color Doppler imaging, performed in one patient, showed a vascular lesion of venous origin that filled when the eye was placed in the direction of the lesion. Varix of the vortex vein is a condition that should be considered in the differential diagnosis of equatorial small choroidal melanoma. The dynamic nature of the lesion is characteristic and diagnostic.

  2. Quantification of Focal Outflow Enhancement Using Differential Canalograms

    PubMed Central

    Loewen, Ralitsa T.; Brown, Eric N.; Scott, Gordon; Parikh, Hardik; Schuman, Joel S.; Loewen, Nils A.

    2016-01-01

    Purpose To quantify regional changes of conventional outflow caused by ab interno trabeculectomy (AIT). Methods Gonioscopic, plasma-mediated AIT was established in enucleated pig eyes. We developed a program to automatically quantify outflow changes (R, package eye-canalogram, github.com) using a fluorescent tracer reperfusion technique. Trabecular meshwork (TM) ablation was demonstrated with fluorescent spheres in six eyes before formal outflow quantification with two-dye reperfusion canalograms in six additional eyes. Eyes were perfused with a central, intracameral needle at 15 mm Hg. Canalograms and histology were correlated for each eye. Results The pig eye provided a model with high similarity to AIT in human patients. Histology indicated ablation of TM and unroofing of most Schlemm's canal segments. Spheres highlighted additional circumferential and radial outflow beyond the immediate area of ablation. Differential canalograms showed that AIT caused an increase of outflow of 17 ± 5-fold inferonasally, 14 ± 3-fold superonasally, and also an increase in the opposite quadrants with a 2 ± 1-fold increase superotemporally, and 3 ± 3 inferotemporally. Perilimbal specific flow image analysis showed an accelerated nasal filling with an additional perilimbal flow direction into adjacent quadrants. Conclusions A quantitative, differential canalography technique was developed that allows us to quantify supraphysiological outflow enhancement by AIT. PMID:27227352

  3. Milky Way Kinematics. II. A Uniform Inner Galaxy H I Terminal Velocity Curve

    NASA Astrophysics Data System (ADS)

    McClure-Griffiths, N. M.; Dickey, John M.

    2016-11-01

    Using atomic hydrogen (H I) data from the VLA Galactic Plane Survey, we measure the H I terminal velocity as a function of longitude for the first quadrant of the Milky Way. We use these data, together with our previous work on the fourth Galactic quadrant, to produce a densely sampled, uniformly measured, rotation curve of the northern and southern Milky Way between 3 {kpc}\\lt R\\lt 8 {kpc}. We determine a new joint rotation curve fit for the first and fourth quadrants, which is consistent with the fit we published in McClure-Griffiths & Dickey and can be used for estimating kinematic distances interior to the solar circle. Structure in the rotation curves is now exquisitely well defined, showing significant velocity structure on lengths of ˜200 pc, which is much greater than the spatial resolution of the rotation curve. Furthermore, the shape of the rotation curves for the first and fourth quadrants, even after subtraction of a circular rotation fit shows a surprising degree of correlation with a roughly sinusoidal pattern between 4.2\\lt R\\lt 7 kpc.

  4. Mapping the global football field: a sociological model of transnational forces within the world game.

    PubMed

    Giulianotti, Richard; Robertson, Roland

    2012-06-01

    This paper provides a sociological model of the key transnational political and economic forces that are shaping the 'global football field'. The model draws upon, and significantly extends, the theory of the 'global field' developed previously by Robertson. The model features four quadrants, each of which contains a dominant operating principle, an 'elemental reference point', and an 'elemental theme'. The quadrants contain, first, neo-liberalism, associated with the individual and elite football clubs; second, neo-mercantilism, associated with nation-states and national football systems; third, international relations, associated with international governing bodies; and fourth, global civil society, associated with diverse institutions that pursue human development and/or social justice. We examine some of the interactions and tensions between the major institutional and ideological forces across the four quadrants. We conclude by examining how the weakest quadrant, featuring global civil society, may gain greater prominence within football. In broad terms, we argue that our four-fold model may be utilized to map and to examine other substantive research fields with reference to globalization. © London School of Economics and Political Science 2012.

  5. Investigation of reliability attributes and accelerated stress factors on terrestrial solar cells

    NASA Technical Reports Server (NTRS)

    Lathrop, J. W.; Prince, J. L.

    1980-01-01

    Three tasks were undertaken to investigate reliability attributes of terrestrial solar cells: (1) a study of the electrical behavior of cells in the second (reverse) quadrant; (2) the accelerated stress testing of three new state-of-the-art cells; and (3) the continued bias-temperature testing of four block 2 type silicon cells at 78 C and 135 C. Electrical characteristics measured in the second quadrant were determined to be a function of the cell's thermal behavior with breakdown depending on the initiation of localized heating. This implied that high breakdown cells may be more fault tolerant when forced to operate in the second quadrant, a result contrary to conventional thinking. The accelerated stress tests used in the first (power) quadrant were bias-temperature, bias-temperature-humidity, temperature-humidity, thermal shock, and thermal cycle. The new type cells measured included an EFG cell, a polycrystalline cell, and a Czochralski cell. Significant differences in the response to the various tests were observed between cell types. A microprocessed controlled, short interval solar cell tester was designed and construction initiated on a prototype.

  6. Simulating the growth of an charge cloud for a microchannel plate detector

    NASA Astrophysics Data System (ADS)

    Siwal, Davinder; Wiggins, Blake; Desouza, Romualdo

    2015-10-01

    Position sensitive microchannel plate (MCP) detectors have a variety of applications in the fields of astronomy, medical imaging, neutron imaging, and ion beam tracking. Recently, a novel approach has been implemented to detect the position of an incident particle. The charge cloud produced by the MCP induces a signal on a wire harp placed between the MCP and an anode. On qualitative grounds it is clear that in this detector the induced signal shape depends on the size of the electron cloud. A detailed study has therefore been performed to investigate the size of the charge cloud within the MCP and its growth as it propagates from the MCP to the anode. A simple model has been developed to calculate the impact of charge repulsion on the growth of the electron cloud. Both the details of the model and its predictions will be presented. Supported by the US DOE NNSA under Award No. DE-NA0002012.

  7. Space and time resolved emission of hard X-rays from a plasma focus

    NASA Technical Reports Server (NTRS)

    Harries, W. L.; Lee, J. H.; Mcfarland, D. R.

    1978-01-01

    The X-ray emission from focused plasmas was observed with an image converter camera in the streak and framing modes. Use of a very high gain image intensifier enabled weak hard X-ray emission (above 25 keV) to be recorded. The use of an admixture of higher atomic number into the deuterium was avoided, and the role of the vapor from the anode surface could be discerned. The recorded bremsstrahlung emission seemed to be from a metallic plasma of copper released from the anode surface by bombardment from an intense electron beam. The intensity of emission was determined by the density of copper and the density and energy of the electron beam. The main emission recorded occurred several 100 nsec after the focus was over, which implies that the electric fields driving the beam existed for this duration. It is suggested that the fields were created by annihilation of magnetic flux for a time much longer than the focus duration.

  8. Analysis of Al2O3 Nanostructure Using Scanning Microscopy

    PubMed Central

    Kubica, Marek; Bara, Marek

    2018-01-01

    It has been reported that the size and shape of the pores depend on the structure of the base metal, the type of electrolyte, and the conditions of the anodizing process. The paper presents thin Al2O3 oxide layer formed under hard anodizing conditions on a plate made of EN AW-5251 aluminum alloy. The oxidation of the ceramic layer was carried out for 40–80 minutes in a three-component SAS electrolyte (aqueous solution of acids: sulphuric 33 ml/l, adipic 67 g/l, and oxalic 30 g/l) at a temperature of 293–313 K, and the current density was 200–400 A/m2. Presented images were taken by a scanning microscope. A computer analysis of the binary images of layers showed different shapes of pores. The structure of ceramic Al2O3 layers is one of the main factors determining mechanical properties. The resistance to wear of specimen-oxide coating layer depends on porosity, morphology, and roughness of the ceramic layer surface. A 3D oxide coating model, based on the computer analysis of images from a scanning electron microscope (Philips XL 30 ESEM/EDAX), was proposed. PMID:29861823

  9. [Clinical and radiographic correlation after anterior cruciate ligament reconstruction].

    PubMed

    González Perales, Aldo Alán; Negrete Corona, Jorge; Chávez Hinojosa, Edgard

    2010-01-01

    The purpose of this work is to correlate the clinical, functional and radiographic results of the anterior cruciate ligament (ACL) reconstruction with the angulation and orientation of the femoral and tibial tunnels. The ACL is one of the most frequently injured articular structures of the knee. The reason for this being that it is the primary limiting structure of anterior tibial translation; its tear causes kinematic alterations and results in long-term degenerative and functional changes. Repair can restore the kinematics. 26 patients, 20-50 years old, post-ACL reconstruction with the semitendinous-gracilis technique. From November 2006 to July 2007. Clinical and functional assessments: Tegner and Lysholm. Radiographic assessment: anteroposterior view with knee extension and lateral view with 30 degrees flexion. Pearson correlations (r) were used in the analysis. 26 patients (100%), 20 males (76.92%), 6 females (23.08%). Mean of 2.4 in the Lysholm scale (fair to good); standard deviation 1.2. Bernard-Lysholm quadrant r = -0.772. Tegner quadrant r = 0.790. The Lysholm and Tegner scale is associated with the graft quadrant. The situation of the tibial implant in the saggital plane is associated with the Lysholm scale. The correlation of patients with an inadequate placement with respect to the quadrants was associated with good-to-excellent results and fair-to-good results. Two patients had a poor clinical outcome; the orientation of the AP angle and the quadrant were within acceptable parameters, with the exception of the lateral angle-shaft axis.

  10. Multi-length scale tomography for the determination and optimization of the effective microstructural properties in novel hierarchical solid oxide fuel cell anodes

    NASA Astrophysics Data System (ADS)

    Lu, Xuekun; Taiwo, Oluwadamilola O.; Bertei, Antonio; Li, Tao; Li, Kang; Brett, Dan J. L.; Shearing, Paul R.

    2017-11-01

    Effective microstructural properties are critical in determining the electrochemical performance of solid oxide fuel cells (SOFCs), particularly when operating at high current densities. A novel tubular SOFC anode with a hierarchical microstructure, composed of self-organized micro-channels and sponge-like regions, has been fabricated by a phase inversion technique to mitigate concentration losses. However, since pore sizes span over two orders of magnitude, the determination of the effective transport parameters using image-based techniques remains challenging. Pioneering steps are made in this study to characterize and optimize the microstructure by coupling multi-length scale 3D tomography and modeling. The results conclusively show that embedding finger-like micro-channels into the tubular anode can improve the mass transport by 250% and the permeability by 2-3 orders of magnitude. Our parametric study shows that increasing the porosity in the spongy layer beyond 10% enhances the effective transport parameters of the spongy layer at an exponential rate, but linearly for the full anode. For the first time, local and global mass transport properties are correlated to the microstructure, which is of wide interest for rationalizing the design optimization of SOFC electrodes and more generally for hierarchical materials in batteries and membranes.

  11. Oxygen suppresses light-driven anodic current generation by a mixed phototrophic culture.

    PubMed

    Darus, Libertus; Ledezma, Pablo; Keller, Jürg; Freguia, Stefano

    2014-12-02

    This paper describes the detrimental effect of photosynthetically evolved oxygen on anodic current generation in the presence of riboflavin upon illumination of a mixed phototrophic culture enriched from a freshwater pond at +0.6 V vs standard hydrogen electrode. In the presence of riboflavin, the phototrophic biomass in the anodic compartment produced an electrical current in response to light/dark cycles (12 h/12 h) over 12 months of operation, generating a maximum current density of 17.5 mA x m(-2) during the dark phase, whereas a much lower current of approximately 2 mA x m(-2) was generated during illumination. We found that the low current generation under light exposure was caused by high rates of reoxidation of reduced riboflavin by oxygen produced during photosynthesis. Quantification of biomass by fluorescence in situ hybridization images suggested that green algae were predominant in both the anode-based biofilm (55.1%) and the anolyte suspension (87.9%) with the remaining biovolume accounted for by bacteria. Genus-level sequencing analysis revealed that bacteria were dominated by cyanobacterium Leptolyngbia (∼35%), while the prevailing algae were Dictyosphaerium, Coelastrum, and Auxenochlorella. This study offers a key comprehension of mediator sensitivity to reoxidation by dissolved oxygen for improvement of microbial solar cell performance.

  12. A novel sputtered Pd mesh architecture as an advanced electrocatalyst for highly efficient hydrogen production

    NASA Astrophysics Data System (ADS)

    de Lucas-Consuegra, Antonio; de la Osa, Ana R.; Calcerrada, Ana B.; Linares, José J.; Horwat, David

    2016-07-01

    This study reports the preparation, characterization and testing of a sputtered Pd mesh-like anode as an advanced electrocatalyst for H2 production from alkaline ethanol solutions in an Alkaline Membrane Electrolyzer (AEM). Pd anodic catalyst is prepared by magnetron sputtering technique onto a microfiber carbon paper support. Scanning Electron Microscopy images reveal that the used preparation technique enables to cover the surface of the carbon microfibers exposed to the Pd target, leading to a continuous network that also maintains part of the original carbon paper macroporosity. Such novel anodic architecture (organic binder free) presents an excellent electro-chemical performance, with a maximum current density of 700 mA cm-2 at 1.3 V, and, concomitantly, a large H2 production rate with low energy requirement compared to water electrolysis. Potassium hydroxide emerges as the best electrolyte, whereas temperature exerts the expected promotional effect up to 90 °C. On the other hand, a 1 mol L-1 ethanol solution is enough to guarantee an efficient fuel supply without any mass transfer limitation. The proposed system also demonstrates to remain stable over 150 h of operation along five consecutives cycles, producing highly pure H2 (99.999%) at the cathode and potassium acetate as the main anodic product.

  13. Relationship between intraocular pressure and angle configuration: an anterior segment OCT study.

    PubMed

    Chong, Rachel S; Sakata, Lisandro M; Narayanaswamy, Arun K; Ho, Sue-Wei; He, Mingguang; Baskaran, Mani; Wong, Tien Yin; Perera, Shamira A; Aung, Tin

    2013-03-05

    To assess the relationship between intraocular pressure (IOP) and anterior chamber angle (ACA) configuration as assessed by gonioscopy and anterior segment optical coherence tomography (AS-OCT). A total of 2045 subjects aged 50 years and older, were recruited from a community clinic and underwent AS-OCT, Goldmann applanation tonometry, and gonioscopy. A quadrant was classified as closed on gonioscopy if the posterior trabecular meshwork could not be seen. A closed quadrant on AS-OCT was defined by the presence of any contact between the iris and angle wall anterior to the scleral spur. Customized software (Zhongshan Angle Assessment Program, Guangzhou, China) was used to measure AS-OCT parameters on AS-OCT scans, including anterior chamber depth, area, and volume; iris thickness (IT) and curvature; lens vault; angle opening distance; and trabecular-iris space area. IOP values were adjusted for age, sex, diabetes and hypertension status, body mass index, central corneal thickness, and presence of peripheral anterior synechiae. Mean age of study subjects was 63.2 ± 8.0 years, 52.6% were female, and 89.4% were Chinese. Mean IOP was 14.8 ± 2.4 mm Hg (range 826). IOP (mean ± SE) increased with number of quadrants with gonioscopic angle closure (none: 14.6 ± 0.2; one: 14.7 ± 0.3; two: 15.0 ± 0.3; three: 15.0 ± 0.3; four: 15.6 ± 0.3 mm Hg; P < 0.001), and on AS-OCT (none: 14.7 ± 0.2; one: 15.0 ± 0.2; two: 14.8 ± 0.2; three: 15.1 ± 0.3; four: 16.0 ± 0.3 mm Hg; P < 0.001). IOP also increased in association with most of the ACA quantitative parameters measured on AS-OCT images, except for IT and lens vault. There was an association between the extent of angle closure, as assessed on AS-OCT and gonioscopy, with increasing IOP.

  14. US-guided percutaneous cholecystostomy: features predicting culture-positive bile and clinical outcome.

    PubMed

    Sosna, Jacob; Kruskal, Jonathan B; Copel, Laurian; Goldberg, S Nahum; Kane, Robert A

    2004-03-01

    To assess sonographic and clinical features that might be used to predict infected bile and/or patient outcome from ultrasonography (US)-guided percutaneous cholecystostomy. Between February 1997 and August 2002 at one institution, 112 patients underwent US-guided percutaneous cholecystostomy (59 men, 53 women; average age, 69.3 years). All US images were scored on a defined semiquantitative scale according to preset parameters: (a) gallbladder distention, (b) sludge and/or stones, (c) wall appearance, (d) pericholecystic fluid, and (e) common bile duct size and/or choledocholithiasis. Separate and total scores were generated. Retrospective evaluation of (a) the bacteriologic growth of aspirated bile and its color and (b) clinical indices (fever, white blood cell count, bilirubin level, liver function test results) was conducted by reviewing medical records. For each patient, the clinical manifestation was classified into four groups: (a) localized right upper quadrant symptoms, (b) generalized abdominal symptoms, (c) unexplained sepsis, or (d) sepsis with other known infection. Logistic regression models, exact Wilcoxon-Mann-Whitney test, and the Kruskal-Wallis test were used. Forty-seven (44%) of 107 patients had infected bile. A logistic regression model showed that wall appearance, distention, bile color, and pericholecystic fluid were not individually significant predictors for culture-positive bile, leaving sludge and/or stones (P =.003, odds ratio = 1.647), common bile duct status (P =.02, odds ratio = 2.214), and total score (P =.007, odds ratio = 1.267). No US covariates or clinical indices predicted clinical outcome. Clinical manifestation was predictive of clinical outcome (P =.001) and aspirating culture-positive bile (P =.008); specifically, 30 (86%) of 35 patients with right upper quadrant symptoms had their condition improve, compared with one (7%) of 15 asymptomatic patients with other known causes of infection. US variables can be used to predict culture-positive bile but not patient outcome. Clinical manifestation is important because patients with right upper quadrant symptoms have the best clinical outcome. Copyright RSNA, 2004

  15. Predictive Value of Primary Tumor Site for Loco-regional Recurrence in Early Breast Cancer Patients with One to Three Positive Axillary Lymphadenophy.

    PubMed

    Niu, Shaoqing; Wen, Ge; Ren, Yufeng; Li, Yiyang; Feng, Lingling; Wang, Chengtao; Huang, Xiaobo; Wen, Bixiu; Zhang, Yujing

    2017-01-01

    Introduction: It remains controversial on high risks for early breast cancer patients with one to three axillary nodes after mastectomy who is predisposition to locoregional recurrence. The present study is to investigate the relationship between primary tumor site and loco-regional recurrence (LRR) and explore the predictive value of clinicopathological characteristics in LRR for early breast cancer patients with one to three positive axillary lymph nodes after mastectomy. Methods: We reviewed the clinical data of 656 consecutively diagnosed patients with pT 1-2 N 1 M 0 breast cancer who were treated in Sun Yat-sen University Cancer Center with radical operation without postoperative radiotherapy between March 1998 and December 2010. The primary tumor sites included outer quadrant in 455 patients (69.36%), inner quadrant in 156 patients (23.78%)and central quadrant in 45 patients (6.86%). LRR and LRR-free survival (LRFS) in combination with clinical and pathological features were analyzed to screen out patients with higher risk of LRR. Results: The median follow-up time was 64.9 months. The 5-, 10-year LRR for the cohort was 8.6% and 12.9%, respectively; the 5-, 10-year LRFS was 86.2% and 76.4%, respectively. Multivariate analyses showed that age of ≤35 years, inner quadrant tumor and non-luminal subtype were independent risk factors for LRR and LRFS. Patients with primary tumor in inner quadrant showed higher LRR and poorer LRFS when risk factors are ≥2 than those with tumors in other sites. Conclusions: Inner quadrant tumor was an independent predictor for LRR and LRFS in patients with early breast cancer and one to three positive axillary lymph nodes, which would be more accurate in combination with other prognostic indexes including patients' age, pathological T stage, Ki67 status, molecular subtypes.

  16. In vivo precision of conventional and digital methods for obtaining quadrant dental impressions.

    PubMed

    Ender, Andreas; Zimmermann, Moritz; Attin, Thomas; Mehl, Albert

    2016-09-01

    Quadrant impressions are commonly used as alternative to full-arch impressions. Digital impression systems provide the ability to take these impressions very quickly; however, few studies have investigated the accuracy of the technique in vivo. The aim of this study is to assess the precision of digital quadrant impressions in vivo in comparison to conventional impression techniques. Impressions were obtained via two conventional (metal full-arch tray, CI, and triple tray, T-Tray) and seven digital impression systems (Lava True Definition Scanner, T-Def; Lava Chairside Oral Scanner, COS; Cadent iTero, ITE; 3Shape Trios, TRI; 3Shape Trios Color, TRC; CEREC Bluecam, Software 4.0, BC4.0; CEREC Bluecam, Software 4.2, BC4.2; and CEREC Omnicam, OC). Impressions were taken three times for each of five subjects (n = 15). The impressions were then superimposed within the test groups. Differences from model surfaces were measured using a normal surface distance method. Precision was calculated using the Perc90_10 value. The values for all test groups were statistically compared. The precision ranged from 18.8 (CI) to 58.5 μm (T-Tray), with the highest precision in the CI, T-Def, BC4.0, TRC, and TRI groups. The deviation pattern varied distinctly depending on the impression method. Impression systems with single-shot capture exhibited greater deviations at the tooth surface whereas high-frame rate impression systems differed more in gingival areas. Triple tray impressions displayed higher local deviation at the occlusal contact areas of upper and lower jaw. Digital quadrant impression methods achieve a level of precision, comparable to conventional impression techniques. However, there are significant differences in terms of absolute values and deviation pattern. With all tested digital impression systems, time efficient capturing of quadrant impressions is possible. The clinical precision of digital quadrant impression models is sufficient to cover a broad variety of restorative indications. Yet the precision differs significantly between the digital impression systems.

  17. Evaluation of posterior ocular changes using enhanced depth imaging-optical coherence tomography in patients with obstructive sleep apnea syndrome.

    PubMed

    Yuvacı, İsa; Pangal, Emine; Bayram, Nurettin; Yüksel, Sevgi Arık; Alabay, Bedirhan; Ağadayı, Alperen; Sırakaya, Ender; Gülhan, Ahmet

    2016-01-01

    Evaluation of the nerve fiber thicknesses of the macula, choroid, and retina using the apnea-hypopnea index in individuals with obstructive sleep apnea syndrome (OSAS) without systemic components. Prospective, controlled study. The central macular, choroidal, and retinal nerve fiber layer (RNFL) thicknesses were evaluated using enhanced depth imaging-spectral domain optical coherence tomography in individuals with OSAS. In people with severe OSAS who had received treatment, posterior ocular structures were examined over 3 months (4th and 12th weeks), and changes were evaluated. Only the right eyes of the participants were evaluated in the study. A total of 72 people were involved in the study, with 18 in the control group and 19 with mild, 16 with moderate, and 19 with severe OSAS. No significant difference was found among the groups in terms of demographic measures. No significant differences were found among the groups in terms of the measures of central macular, central subfoveal choroidal (CSCT), temporal choroidal, nasal choroidal, and RNFL thicknesses. In severe OSAS cases in which treatment was administered, although subjective clinical recovery was observed, statistically significant thinning was detected during the 3-month follow-up period in the CSCT, general RNFL, as well as in the inferior and superior nasal quadrants, and temporal superior quadrant (p=0.005, p=0.009, p=0.039, p=0.003, and p=0.02, respectively). In the group with severe OSAS, thinning in some posterior ocular tissues was observed. Although patients with severe OSAS may experience clinical recovery, we recommend that they would be followed up in terms of ocular ischemic injury.

  18. Diagnosing the Neutral Interstellar Gas Flow at 1 AU with IBEX-Lo

    NASA Astrophysics Data System (ADS)

    Möbius, E.; Kucharek, H.; Clark, G.; O'Neill, M.; Petersen, L.; Bzowski, M.; Saul, L.; Wurz, P.; Fuselier, S. A.; Izmodenov, V. V.; McComas, D. J.; Müller, H. R.; Alexashov, D. B.

    2009-08-01

    Every year in fall and spring the Interstellar Boundary Explorer (IBEX) will observe directly the interstellar gas flow at 1 AU over periods of several months. The IBEX-Lo sensor employs a powerful triple time-of-flight mass spectrometer. It can distinguish and image the O and He flow distributions in the northern fall and spring, making use of sensor viewing perpendicular to the Sun-pointing spin axis. To effectively image the narrow flow distributions IBEX-Lo has a high angular resolution quadrant in its collimator. This quadrant is employed selectively for the interstellar gas flow viewing in the spring by electrostatically shutting off the remainder of the aperture. The operational scenarios, the expected data, and the necessary modeling to extract the interstellar parameters and the conditions in the heliospheric boundary are described. The combination of two key interstellar species will facilitate a direct comparison of the pristine interstellar flow, represented by He, which has not been altered in the heliospheric boundary region, with a flow that is processed in the outer heliosheath, represented by O. The O flow distribution consists of a depleted pristine component and decelerated and heated neutrals. Extracting the latter so-called secondary component of interstellar neutrals will provide quantitative constraints for several important parameters of the heliosheath interaction in current global heliospheric models. Finding the fraction and width of the secondary component yields an independent value for the global filtration factor of species, such as O and H. Thus far filtration can only be inferred, barring observations in the local interstellar cloud proper. The direction of the secondary component will provide independent information on the interstellar magnetic field strength and orientation, which has been inferred from SOHO SWAN Ly- α backscattering observations and the two Voyager crossings of the termination shock.

  19. Appositional Closure Identified by Ultrasound Biomicroscopy in Population-Based Primary Angle-Closure Glaucoma Suspects: The Liwan Eye Study

    PubMed Central

    Kong, Xiangbin; Foster, Paul J.; Huang, Qunxiao; Zheng, Yingfeng; Huang, Wenyong; Cai, Xiaoyu

    2011-01-01

    Purpose. To describe the characteristics of the iridocorneal angle using ultrasound biomicroscopy (UBM) in Chinese people classified gonioscopically as having suspected primary angle-closure (PACS) glaucoma. Methods. PACS were defined as not having visible posterior (usually pigmented) trabecular meshwork in two or more quadrants examined by static gonioscopy. The PACS and 1 of 10 those who did not meet this criterion were identified from a population-based survey. Iridotrabecular meshwork contact (ITC) was identified and further classified into low and high, according to standard UBM images. Those with high ITC were further classified according the configuration of ITC: B-type, with contiguous ITC from the base of the angle, and S-type, with ITC localized to the region of Schwalbe's line. Results. ITC was identified in 78.6% of the superior, 40.2% of the nasal, 59.8% of the inferior, and 25.6% of the temporal quadrants in the PACS (n = 117). These proportions were 43.9%, 15.8%, 29.8%, and 14.0% in the controls (n = 57), respectively. About two thirds of the eyes with ITC were classified as high. In those with high ITC, the number with B- and S-type ITC was very similar. The proportions of any high ITCs increased substantially from 15.4% in those with Shaffer angle grade 4 and 45.0% in grade 3, to 71.0% in grade 2, 70.2% in grade 1, and 86.4% in grade 0. Conclusions. More ITC is identified on UBM imaging than by gonioscopy. Careful consideration should be given to the assessment modality regarded as the reference standard in defining anatomic risk factors for glaucomatous visual loss and the need for treatment. PMID:21357394

  20. Fourier Transformed Infra-Red Imaging of Femoral Neck Bone: Reduced Heterogeneity of Mineral-to-Matrix and Carbonate-to-Phosphate and more Variable Crystallinity in Treatment-Naïve Fracture Cases compared to Fracture-Free Controls

    PubMed Central

    Gourion-Arsiquaud, Samuel; Lukashova, Lyudmilla; Power, Jon; Loveridge, Nigel; Reeve, Jonathan; Boskey, Adele L.

    2012-01-01

    After age 60 hip fracture risk strongly increases, but only a fifth of this increase is attributable to reduced mineral density (BMD, measured clinically). Changes in bone quality, specifically bone composition as measured by Fourier Transform Infrared spectroscopic imaging (FTIRI), also contribute to fracture risk. Here, FTIRI was applied to study the femoral neck and provide spatially derived information on its mineral and matrix properties in age-matched fractured and non-fractured bones. Whole femoral neck cross sections, divided into quadrants along the neck’s axis, from 10 women with hip fracture and 10 cadaveric controls were studied using FTIRI and micro-computed Tomography. Although 3-dimensional micro-CT bone mineral densities were similar, the mineral-to-matrix ratio was reduced in the cases of hip fracture, confirming previous reports. New findings were that the FTIRI microscopic variation (heterogeneity) of the mineral-to-matrix ratio was substantially reduced in the fracture group as was the heterogeneity of the carbonate-to-phosphate ratio. Conversely, the heterogeneity of crystallinity was increased. Increased variation of crystallinity was statistically associated with reduced variation of the carbonate-to-phosphate ratio. Anatomical variation in these properties between the different femoral neck quadrants was reduced in the fracture group compared to controls. While our treatment-naïve patients had reduced rather than increased bending resistance, these changes in heterogeneity associated with hip fracture are in another way comparable to the effects of experimental bisphosphonate therapy, which decreases heterogeneity and other indicators of bone’s toughness as a material. PMID:22865771

  1. Fourier transform infrared imaging of femoral neck bone: reduced heterogeneity of mineral-to-matrix and carbonate-to-phosphate and more variable crystallinity in treatment-naive fracture cases compared with fracture-free controls.

    PubMed

    Gourion-Arsiquaud, Samuel; Lukashova, Lyudmilla; Power, Jon; Loveridge, Nigel; Reeve, Jonathan; Boskey, Adele L

    2013-01-01

    After the age of 60 years, hip fracture risk strongly increases, but only a fifth of this increase is attributable to reduced bone mineral density (BMD, measured clinically). Changes in bone quality, specifically bone composition as measured by Fourier transform infrared spectroscopic imaging (FTIRI), also contribute to fracture risk. Here, FTIRI was applied to study the femoral neck and provide spatially derived information on its mineral and matrix properties in age-matched fractured and nonfractured bones. Whole femoral neck cross sections, divided into quadrants along the neck's axis, from 10 women with hip fracture and 10 cadaveric controls were studied using FTIRI and micro-computed tomography. Although 3-dimensional micro-CT bone mineral densities were similar, the mineral-to-matrix ratio was reduced in the cases of hip fracture, confirming previous reports. New findings were that the FTIRI microscopic variation (heterogeneity) of the mineral-to-matrix ratio was substantially reduced in the fracture group as was the heterogeneity of the carbonate-to-phosphate ratio. Conversely, the heterogeneity of crystallinity was increased. Increased variation of crystallinity was statistically associated with reduced variation of the carbonate-to-phosphate ratio. Anatomical variation in these properties between the different femoral neck quadrants was reduced in the fracture group compared with controls. Although our treatment-naive patients had reduced rather than increased bending resistance, these changes in heterogeneity associated with hip fracture are in another way comparable to the effects of experimental bisphosphonate therapy, which decreases heterogeneity and other indicators of bone's toughness as a material. Copyright © 2013 American Society for Bone and Mineral Research.

  2. Visual performance-based image enhancement methodology: an investigation of contrast enhancement algorithms

    NASA Astrophysics Data System (ADS)

    Neriani, Kelly E.; Herbranson, Travis J.; Reis, George A.; Pinkus, Alan R.; Goodyear, Charles D.

    2006-05-01

    While vast numbers of image enhancing algorithms have already been developed, the majority of these algorithms have not been assessed in terms of their visual performance-enhancing effects using militarily relevant scenarios. The goal of this research was to apply a visual performance-based assessment methodology to evaluate six algorithms that were specifically designed to enhance the contrast of digital images. The image enhancing algorithms used in this study included three different histogram equalization algorithms, the Autolevels function, the Recursive Rational Filter technique described in Marsi, Ramponi, and Carrato1 and the multiscale Retinex algorithm described in Rahman, Jobson and Woodell2. The methodology used in the assessment has been developed to acquire objective human visual performance data as a means of evaluating the contrast enhancement algorithms. Objective performance metrics, response time and error rate, were used to compare algorithm enhanced images versus two baseline conditions, original non-enhanced images and contrast-degraded images. Observers completed a visual search task using a spatial-forcedchoice paradigm. Observers searched images for a target (a military vehicle) hidden among foliage and then indicated in which quadrant of the screen the target was located. Response time and percent correct were measured for each observer. Results of the study and future directions are discussed.

  3. Dual tree fractional quaternion wavelet transform for disparity estimation.

    PubMed

    Kumar, Sanoj; Kumar, Sanjeev; Sukavanam, Nagarajan; Raman, Balasubramanian

    2014-03-01

    This paper proposes a novel phase based approach for computing disparity as the optical flow from the given pair of consecutive images. A new dual tree fractional quaternion wavelet transform (FrQWT) is proposed by defining the 2D Fourier spectrum upto a single quadrant. In the proposed FrQWT, each quaternion wavelet consists of a real part (a real DWT wavelet) and three imaginary parts that are organized according to the quaternion algebra. First two FrQWT phases encode the shifts of image features in the absolute horizontal and vertical coordinate system, while the third phase has the texture information. The FrQWT allowed a multi-scale framework for calculating and adjusting local disparities and executing phase unwrapping from coarse to fine scales with linear computational efficiency. Copyright © 2013 ISA. Published by Elsevier Ltd. All rights reserved.

  4. First light observations with TIFR Near Infrared Imaging Camera (TIRCAM-II)

    NASA Astrophysics Data System (ADS)

    Ojha, D. K.; Ghosh, S. K.; D'Costa, S. L. A.; Naik, M. B.; Sandimani, P. R.; Poojary, S. S.; Bhagat, S. B.; Jadhav, R. B.; Meshram, G. S.; Bakalkar, C. B.; Ramaprakash, A. N.; Mohan, V.; Joshi, J.

    TIFR near infrared imaging camera (TIRCAM-II) is based on the Aladdin III Quadrant InSb focal plane array (512×512 pixels; 27.6 μm pixel size; sensitive between 1 - 5.5 μm). TIRCAM-II had its first engineering run with the 2 m IUCAA telescope at Girawali during February - March 2011. The first light observations with TIRCAM-II were quite successful. Several infrared standard with TIRCAM-II were quite successful. Several infrared standard stars, the Trapezium Cluster in Orion region, McNeil's nebula, etc., were observed in the J, K and in a narrow-band at 3.6 μm (nbL). In the nbL band, some bright stars could be detected from the Girawali site. The performance of TIRCAM-II is discussed in the light of preliminary observations in near infrared bands.

  5. Extended linear detection range for optical tweezers using image-plane detection scheme

    NASA Astrophysics Data System (ADS)

    Hajizadeh, Faegheh; Masoumeh Mousavi, S.; Khaksar, Zeinab S.; Reihani, S. Nader S.

    2014-10-01

    Ability to measure pico- and femto-Newton range forces using optical tweezers (OT) strongly relies on the sensitivity of its detection system. We show that the commonly used back-focal-plane detection method provides a linear response range which is shorter than that of the restoring force of OT for large beads. This limits measurable force range of OT. We show, both theoretically and experimentally, that utilizing a second laser beam for tracking could solve the problem. We also propose a new detection scheme in which the quadrant photodiode is positioned at the plane optically conjugate to the object plane (image plane). This method solves the problem without need for a second laser beam for the bead sizes that are commonly used in force spectroscopy applications of OT, such as biopolymer stretching.

  6. Re-evaluation of differential phase contrast (DPC) in a scanning laser microscope using a split detector as an alternative to differential interference contrast (DIC) optics.

    PubMed

    Amos, W B; Reichelt, S; Cattermole, D M; Laufer, J

    2003-05-01

    In this paper, differential phase imaging (DPC) with transmitted light is implemented by adding a suitable detection system to a standard commercially available scanning confocal microscope. DPC, a long-established method in scanning optical microscopy, depends on detecting the intensity difference between opposite halves or quadrants of a split photodiode detector placed in an aperture plane. Here, DPC is compared with scanned differential interference contrast (DIC) using a variety of biological specimens and objective lenses of high numerical aperture. While DPC and DIC images are generally similar, DPC seems to have a greater depth of field. DPC has several advantages over DIC. These include low cost (no polarizing or strain-free optics are required), absence of a double scanning spot, electronically variable direction of shading and the ability to image specimens in plastic dishes where birefringence prevents the use of DIC. DPC is also here found to need 20 times less laser power at the specimen than DIC.

  7. From the Night Side

    NASA Image and Video Library

    2015-09-14

    The night sides of Saturn and Tethys are dark places indeed. We know that shadows are darker areas than sunlit areas, and in space, with no air to scatter the light, shadows can appear almost totally black. Tethys (660 miles or 1,062 kilometers across) is just barely seen in the lower left quadrant of this image below the ring plane and has been brightened by a factor of three to increase its visibility. The wavy outline of Saturn's polar hexagon is visible at top center. This view looks toward the sunlit side of the rings from about 10 degrees above the ring plane. The image was taken with the Cassini spacecraft wide-angle camera on Jan. 15, 2015 using a spectral filter which preferentially admits wavelengths of near-infrared light centered at 752 nanometers. The view was obtained at a distance of approximately 1.5 million miles (2.4 million kilometers) from Saturn. Image scale is 88 miles (141 kilometers) per pixel. http://photojournal.jpl.nasa.gov/catalog/PIA18333

  8. Wish Upon a Star

    NASA Image and Video Library

    2015-01-05

    What's that bright point of light in the outer A ring? It's a star, bright enough to be visible through the ring! Quick, make a wish! This star -- seen in the lower right quadrant of the image -- was not captured by coincidence, it was part of a stellar occultation. By monitoring the brightness of stars as they pass behind the rings, scientists using this powerful observation technique can inspect detailed structures within the rings and how they vary with location. This view looks toward the sunlit side of the rings from about 44 degrees above the ringplane. The image was taken in visible light with the Cassini spacecraft narrow-angle camera on Oct. 8, 2013. The view was acquired at a distance of approximately 1.1 million miles (1.8 million kilometers) from the rings and at a Sun-Rings-Spacecraft, or phase, angle of 96 degrees. Image scale is 6.8 miles (11 kilometers) per pixel. http://photojournal.jpl.nasa.gov/catalog/PIA18297

  9. Examining Sensory Quadrants in Autism

    ERIC Educational Resources Information Center

    Kern, Janet K.; Garver, Carolyn R.; Carmody, Thomas; Andrews, Alonzo A.; Trivedi, Madhukar H.; Mehta, Jyutika A.

    2007-01-01

    The purpose of this study was to examine sensory quadrants in autism based on Dunn's Theory of Sensory Processing. The data for this study was collected as part of a cross-sectional study that examined sensory processing (using the Sensory Profile) in 103 persons with autism, 3-43 years of age, compared to 103 age- and gender-matched community…

  10. Status of Reconstruction of Fragmented Diamond-on-Silicon Collector From Genesis Spacecraft Solar Wind Concentrator

    NASA Technical Reports Server (NTRS)

    Rodriquez, Melissa C.; Calaway, M. C.; McNamara, K. M.; Hittle, J. D.

    2009-01-01

    In addition to passive solar wind collector surfaces, the Genesis Discovery Mission science canister had on board an electrostatic concave mirror for concentrating the solar wind ions, known as the concentrator . The 30-mm-radius collector focal point (the target) was comprised of 4 quadrants: two of single crystal SiC, one of polycrystalline 13C diamond and one of diamond-like-carbon (DLC) on a silicon substrate. [DLC-on-silicon is also sometimes referenced as Diamond-on-silicon, DOS.] Three of target quadrants survived the hard landing intact, but the DLC-on-silicon quadrant fractured into numerous pieces (Fig. 1). This abstract reports the status of identifying the DLC target fragments and reconstructing their original orientation.

  11. Diagnosis of Upper-Quadrant Lymphedema Secondary to Cancer: Clinical Practice Guideline From the Oncology Section of APTA

    PubMed Central

    Levenhagen, Kimberly; Davies, Claire; Perdomo, Marisa; Ryans, Kathryn

    2017-01-01

    Introduction: The Oncology Section of APTA developed a clinical practice guideline to aid the clinician in diagnosing secondary upper-quadrant cancer-related lymphedema. Methods: Following a systematic review of published studies and a structured appraisal process, recommendations were written to guide the physical therapist and other health care clinicians in their diagnostic process. Overall, clinical practice recommendations were formulated on the basis of the evidence for each diagnostic method and were assigned a grade based on the strength of the evidence for different patient presentations and clinical utility. Recommendations: In an effort to make these clinically applicable, recommendations were based on the characteristics as to the location and stage of a patient's upper-quadrant lymphedema. PMID:28748128

  12. Large field distributed aperture laser semiactive angle measurement system design with imaging fiber bundles.

    PubMed

    Xu, Chunyun; Cheng, Haobo; Feng, Yunpeng; Jing, Xiaoli

    2016-09-01

    A type of laser semiactive angle measurement system is designed for target detecting and tracking. Only one detector is used to detect target location from four distributed aperture optical systems through a 4×1 imaging fiber bundle. A telecentric optical system in image space is designed to increase the efficiency of imaging fiber bundles. According to the working principle of a four-quadrant (4Q) detector, fiber diamond alignment is adopted between an optical system and a 4Q detector. The structure of the laser semiactive angle measurement system is, we believe, novel. Tolerance analysis is carried out to determine tolerance limits of manufacture and installation errors of the optical system. The performance of the proposed method is identified by computer simulations and experiments. It is demonstrated that the linear region of the system is ±12°, with measurement error of better than 0.2°. In general, this new system can be used with large field of view and high accuracy, providing an efficient, stable, and fast method for angle measurement in practical situations.

  13. Assessment of Carotid Plaque Inflammation in Diabetic and Nondiabetic Patients-An Exploratory Ultrasmall Superparamagnetic Iron Oxide-Enhanced Magnetic Resonance Imaging Study.

    PubMed

    Usman, Ammara; Patterson, Andrew J; Sadat, Umar; Tang, Tjun Y; Graves, Martin J; Gillard, Jonathan H

    2017-04-01

    Ultrasmall superparamagnetic iron oxide (USPIO)-enhanced magnetic resonance (MR) imaging enables the identification of inflammation within the atheroma, predominantly by USPIO uptake by macrophages present in atherosclerotic tissue. Diabetic patients, however, may have dysfunctional macrophage activity, which may affect utilization of USPIO in identifying plaque inflammation in this patient cohort. Fifteen diabetic and fifteen nondiabetic patients underwent USPIO-enhanced carotid MR imaging using 1.5T MR system. Pre- and post-USPIO carotid MR images were manually coregistered. The percentage decrease in the signal intensity after USPIO administration was calculated as a relative measure of the USPIO uptake. Diabetic and nondiabetic patients had comparable demographics and comorbidities. The mean global, maximum quadrant, and maximum slice changes showing change in relative signal intensity as a result of USPIO administration were comparable for the two patient cohorts (P > .05). USPIO can identify inflammatory burden with carotid atheroma in both diabetic and nondiabetic patients. Copyright © 2017 National Stroke Association. Published by Elsevier Inc. All rights reserved.

  14. Gentamicin-Eluting Titanium Dioxide Nanotubes Grown on the Ultrafine-Grained Titanium.

    PubMed

    Nemati, Sima Hashemi; Hadjizadeh, Afra

    2017-08-01

    Titanium (Ti)-based materials is the most appropriate choices for the applications as orthopedic and dental implants. In this regard, ultrafine-grained (UFG) titanium with an enhanced mechanical properties and surface energy has attracted more attention. Titanium dioxide (TiO 2 ) nanotubes grown on the titanium could enhance bone bonding, cellular response and are good reservoirs for loading drugs and antibacterial agents. This article investigates gentamicin loading into and release from the TiO 2 nanotubes, grown on the UFG compared to coarse-grained (CG) titanium substrate surfaces. Equal Channel Angular Pressing (ECAP) was employed to produce the UFG structure titanium. TiO 2 nanotubes were grown by the anodizing technique on both UFG and CG titanium substrate surfaces. Scanning electron microscopy (SEM) imaging confirmed TiO 2 nanotube growth on the surface. The UV-vis spectroscopy analysis results show that the amount of gentamicin load-release in the anodized UFG titanium sample is higher than that of CG one which can be explained in terms of thicker TiO 2 nanotube arrays layer formed on UFG sample. Moreover, the anodized UFG titanium samples released the drug in a longer time than CG (1 day for the UFG titanium vs. 3 h for the CG one). Regarding wettability analysis, anodized UFG titanium sample showed more enhanced hydrophilicity than CG counterpart. Therefore, the significantly smaller grain size of pure titanium provided by the ECAP technique coupled with appropriate subsequent anodization treatment not only offers a good combination of biocompatibility and adequate mechanical properties but also it provides a delayed release condition for gentamicin.

  15. Molecular Diagnostics for the Study of Hypersonic Flows

    DTIC Science & Technology

    2000-04-01

    between the at the F4 high-enthalpy wind tunnel [21]. Figure 5 electrodes. The fast electrons exit the anode disk shows the image acquired 90 ms after...Discharge Figure 5 Typical F4 run, flow at 90 ms , Grounded Electrode convection imaged 5 jis after beam emission. Figure 4 Schematic diagram of the...accounts for the classical phenomena like absorption and Figure 6 Velocity profile at 90 ms for run of refraction. X(2) is the second-order

  16. In situ monitoring of corrosion mechanisms and phosphate inhibitor surface deposition during corrosion of zinc-magnesium-aluminium (ZMA) alloys using novel time-lapse microscopy.

    PubMed

    Sullivan, James; Cooze, Nathan; Gallagher, Callum; Lewis, Tom; Prosek, Tomas; Thierry, Dominique

    2015-01-01

    In situ time-lapse optical microscopy was used to examine the microstructural corrosion mechanisms in three zinc-magnesium-aluminium (ZMA) alloy coated steels immersed in 1% NaCl pH 7. Preferential corrosion of MgZn(2) lamellae within the eutectic phases was observed in all the ZMA alloys followed by subsequent dissolution of Zn rich phases. The total extent and rate of corrosion, measured using time-lapse image analysis and scanning vibrating electrode technique (SVET) estimated mass loss, decreased as Mg and Al alloying additions were increased up to a level of 3 wt% Mg and 3.7 wt% Al. This was probably due to the increased presence of MgO and Al(2)O(3) at the alloy surface retarding the kinetics of cathodic oxygen reduction. The addition of 1 × 10(-2) mol dm(-3) Na(3)PO(4) to 1% NaCl pH 7 had a dramatic influence on the corrosion mechanism for a ZMA with passivation of anodic sites through phosphate precipitation observed using time-lapse image analysis. Intriguing rapid precipitation of filamentous phosphate was also observed and it is postulated that these filaments nucleate and grow due to super saturation effects. Polarisation experiments showed that the addition of 1 × 10(-2) mol dm(-3) Na(3)PO(4) to the 1% NaCl electrolyte promoted an anodic shift of 50 mV in open circuit potential for the ZMA alloy with a reduction in anodic current of 2.5 orders of magnitude suggesting that it was acting primarily as an anodic inhibitor supporting the inferences from the time-lapse investigations. These phosphate additions resulted in a 98% reduction in estimated mass loss as measured by SVET demonstrating the effectiveness of phosphate inhibitors for this alloy system.

  17. Analysis of breast thermograms for ROI extraction and description using mathematical morphology

    NASA Astrophysics Data System (ADS)

    Zermeño-Loreto, O. A.; Toxqui-Quitl, C.; Orozco Guillén, E. E.; Padilla-Vivanco, A.

    2017-09-01

    The detection of a temperature increase or hot spots in breast thermograms can be related with high metabolic activity of disease cells. Image processing algorithms to seek mainly temperature increases above 3°C which have a high probability of being a malignancy are proposed. Also a derivative operator is used to highlights breast regions of interest (ROI). In order to determinate a medical alert, a feature descriptor of the ROI is constructed using its maximum temperature, maximum increase of temperature, sector/quadrant position in the breast, and area. The proposed algorithms are tested in a home database and a public database for mastology research.

  18. Sclerosant extravasation as a complication of sclerosing endotherapy for bleeding gastric varices.

    PubMed

    Cheng, H-C; Cheng, P-N; Tsai, Y-M; Tsai, H-M; Chen, C-Y

    2004-03-01

    We report here the case of a 65-year-old woman who suffered intraperitoneal sclerosant leakage after endoscopic injection sclerotherapy for bleeding gastric varices. In total, 3 ml of N-butyl-2-cyanoacrylate and Lipiodol mixture was injected. The patient developed mild fever and pain over the left upper quadrant and flank after the procedure. In addition to a Lipiodol-filled gastric varix, the imaging studies disclosed a wide spread of Lipiodol over the left peritoneal cavity. The patient was kept fasting with parenteral antibiotics and nutrition. She responded well to the treatment, and all of the symptoms had subsided 6 days later.

  19. Primary secretory otitis media in Cavalier King Charles spaniels.

    PubMed

    Cole, Lynette K

    2012-11-01

    Primary secretory otitis media (PSOM) is a disease that has been described in the Cavalier King Charles spaniel (CKCS). A large, bulging pars flaccida identified on otoscopic examination confirms the diagnosis. However, in many CKCS with PSOM the pars flaccida is flat, and radiographic imaging is needed to confirm the diagnosis. Current treatment for PSOM includes performing a myringotomy into the caudal-ventral quadrant of the pars tensa with subsequent flushing of the mucus out of the bulla using a video otoscope. Repeat myringotomies and flushing of the middle ear are necessary to keep the middle ear free of mucus. Copyright © 2012 Elsevier Inc. All rights reserved.

  20. Diagnostic Capability of Peripapillary Retinal Volume Measurements in Glaucoma.

    PubMed

    Simavli, Huseyin; Poon, Linda Yi-Chieh; Que, Christian J; Liu, Yingna; Akduman, Mustafa; Tsikata, Edem; de Boer, Johannes F; Chen, Teresa C

    2017-06-01

    To determine the diagnostic capability of spectral domain optical coherence tomography peripapillary retinal volume (RV) measurements. A total of 156 patients, 89 primary open-angle glaucoma and 67 normal subjects, were recruited. Spectral domain optical coherence tomography peripapillary RV was calculated for 4 quadrants using 3 annuli of varying scan circle diameters: outer circumpapillary annuli of circular grids 1, 2, and 3 (OCA1, OCA2, OCA3). Area under the receiver operating characteristic curves and pairwise comparisons of receiver operating characteristic (ROC) curves were performed to determine which quadrants were best for diagnosing primary open-angle glaucoma. The pairwise comparisons of the best ROC curves for RV and retinal nerve fiber layer (RNFL) were performed. The artifact rates were analyzed. Pairwise comparisons showed that the smaller annuli OCA1 and OCA2 had better diagnostic performance than the largest annulus OCA3 (P<0.05 for all quadrants). OCA1 and OCA2 had similar diagnostic performance, except for the inferior quadrant which was better for OCA1 (P=0.0033). The pairwise comparisons of the best ROC curves for RV and RNFL were not statistically significant. RV measurements had lower rates of artifacts at 7.4% while RNFL measurements had higher rates at 42.9%. Peripapillary RV measurements have excellent ability for diagnosing not only glaucoma patients but also a subset of early glaucoma patients. The inferior quadrant of peripapillary annulus OCA1 demonstrated the best diagnostic capability for both glaucoma and early glaucoma. The diagnostic ability of RV is comparable with that of RNFL parameters in glaucoma but with lower artifact rates.

  1. Diagnostic Capability of Peripapillary Retinal Volume Measurements in Glaucoma

    PubMed Central

    Simavli, Huseyin; Poon, Linda Yi-Chieh; Que, Christian John; Liu, Yingna; Akduman, Mustafa; Tsikata, Edem; de Boer, Johannes F.; Chen, Teresa C.

    2017-01-01

    Purpose To determine the diagnostic capability of spectral domain optical coherence tomography (SD-OCT) peripapillary retinal volume (RV) measurements. Materials and Methods A total of 156 patients, 89 primary open angle (POAG) and 67 normal subjects, were recruited. SD-OCT peripapillary RV was calculated for four quadrants using 3 annuli of varying scan circle diameters: outer circumpapillary annuli of circular grids 1, 2, and 3 (OCA1, OCA2, OCA3). Area under the receiver operating characteristic (AUROC) curves and pairwise comparisons of receiver operating characteristic (ROC) curves were performed to determine which quadrants were best for diagnosing POAG. The pairwise comparisons of the best ROC curves for RV and RNFL were performed. The artifact rates were analyzed. Results Pairwise comparisons showed that the smaller annuli OCA1 and OCA2 had better diagnostic performance than the largest annulus OCA3 (p<0.05 for all quadrants). OCA1 and OCA2 had similar diagnostic performance, except for the inferior quadrant which was better for OCA1 (p=0.0033).The pairwise comparisons of the best ROC curves for RV and RNFL were not statistically significant. Retinal volume measurements had lower rates of artifacts at 7.4% while RNFL measurements had higher rates at 42.9%. Conclusion Peripapillary RV measurements have excellent ability for diagnosing not only glaucoma patients but also a subset of early glaucoma patients. The inferior quadrant of peripapillary annulus OCA1 demonstrated the best diagnostic capability for both glaucoma and early glaucoma. The diagnostic ability of RV is comparable to that of RNFL parameters in glaucoma but with lower artifact rates. PMID:28079657

  2. Diagnostic Power of Macular Retinal Thickness Analysis and Structure-Function Relationship in Glaucoma Diagnosis Using SPECTRALIS OCT.

    PubMed

    Rolle, Teresa; Manerba, Linda; Lanzafame, Pietro; Grignolo, Federico M

    2016-05-01

    To evaluate the diagnostic power of the Posterior Pole Asymmetry Analysis (PPAA) from the SPECTRALIS OCT in glaucoma diagnosis and to define the correlation between the visual field sensitivity (VFS) and macular retinal thickness (MRT). 90 consecutive open-angle glaucoma patients and 23 healthy subjects were enrolled. All subjects underwent Visual Field test (Humphrey Field Analyzer, central 24-2 SITA-Standard) and SD-OCT volume scans (SPECTRALIS, Posterior Pole Asymmetry Analysis). The areas under the Receiving Operating Characteristic curve (AROC) were calculated to assess discriminating power for glaucoma, at first considering total MRT values and hemisphere MRT value and then quadrant MRT values from 16 square cells in a 8 x 8 posterior pole retinal thickness map that were averaged for a mean retinal thickness value. Structure function correlation was performed for total values, hemisphere values and for each quadrant compared to the matching central test points of the VF. The AROCs ranged from 0.70 to 0.82 (p < 0.0001), with no significant differences between each other. The highest AROC observed was in inferior nasal quadrant. The VFS showed a strong correlation only with the corresponding MRT value s for quadrant analysis: Superior Temporal (r = 0.33, p = 0.0013), Superior Nasal (r = 0.43, p < 0.0001), Inferior Temporal (r = 0.57, p < 0.0001) and Inferior Nasal (r = 0.55, p < 0.0001). the quadrant analysis showed statistically significant structure-function correlations and may provide additional data for the diagnostic performance of SPECTRALIS OCT.

  3. Comparing the efficiency of Er,Cr:YSGG laser and diode laser on human β-defensin-1 and IL-1β levels during the treatment of generalized aggressive periodontitis and chronic periodontitis.

    PubMed

    Ertugrul, Abdullah Seckin; Tekin, Yasin; Talmac, Ahmet Cemil

    2017-11-01

    The aim of this study is to determine the suitability of the Er,Cr:YSGG and 940 ± 15-nm diode laser for the treatment of generalized aggressive periodontitis and chronic periodontitis by measuring the levels of human β-defensin-1 and IL-1β. A total of 26 patients were included in this study. The study was designed as a "split-mouth" experiment. We performed scaling and root planing in the right maxillary quadrant, scaling and root planning + Er,Cr:YSGG laser in the left maxillary quadrant, scaling and root planning + 940 ± 15-nm diode laser in the left mandibular quadrant, and only scaling and root planing in the right mandibular quadrant. The presence of human β-defensin-1 and IL-1β was analyzed with an ELISA. When the baseline and post-treatment human β-defensin-1 levels and IL-1β levels of the study groups were evaluated, a decrease in human β-defensin-1 and IL-1β were observed in the quadrant where the Er,Cr:YSGG laser was applied in both the generalized aggressive periodontitis group and the chronic periodontitis group. The use of the Er,Cr:YSGG laser at non-surgical periodontal treatment decreased both IL-1β and human β-defensin-1 levels. It is likely that Er,Cr:YSGG laser is more suitable for the treatment of generalized aggressive periodontitis and chronic periodontitis.

  4. Optical coherence tomography in papilledema and pseudopapilledema with and without optic nerve head drusen.

    PubMed

    Bassi, Shikha Talwar; Mohana, Kuppuswamy Parthasarthy

    2014-12-01

    To compare the spectral domain optical coherence tomography (SD-OCT) findings of the optic disc and the peripapillary retina of patients with a true papilledema and pseudopapilledema with and without optic nerve head drusen (ONHD). Retrospective Case Control Study. Peripapillary retinal nerve fiber layer (PPRNFL) thickness as depicted by SD-OCT of 94 eyes of 66 patients with papilledema (30 eyes), pseudopapiledema (31 eyes), and normal controls (33 eyes) was analyzed. The mean RNFL thickness, total retinal thickness (TRT) at a superior and inferior edge of the disc and the quadrant wise topography of increased RNFL were compared in all three groups. Sensitivity, specificity, and area under the receiver operating characteristic curve (AROC) were calculated for all the parameters. The median RNFL thickness was 185.4 (129.5-349.3 μm), 122.3 (109-156.3 μm) and 91.62 ± 7 μm in papilledema, pseudopapilledema, and controls, respectively. Papilledema group had thicker PPRNFL in all quadrants except temporal quadrant. TRT was thicker in papilledema and pseudopapilledema compared to controls. ONHD could be directly visualized as high reflective clumps in the sub-retinal space or the RNFL in 30 eyes. Increased RNFL thickness in all four quadrants was noted 43.3% in papilledema and 9.7% in pseudopapilledema. Normal RNFL thickness in all four quadrants was noted in 0% in papilledema and 32.3% in pseudopapilledema. Nasal RNFL had the highest AROC (0.792) indicating high diagnostic ability to differentiate papilledema from pseudopapilledema. SD-OCT can be used as a tool to differentiate between papilledema and pseudopapilledema.

  5. Changes in retinal microvascular diameter in patients with diabetes

    PubMed Central

    da Silva, Andréa Vasconcellos Batista; Gouvea, Sonia Alves; da Silva, Aurélio Paulo Batista; Bortolon, Saulo; Rodrigues, Anabel Nunes; Abreu, Glaucia Rodrigues; Herkenhoff, Fernando Luiz

    2015-01-01

    Background and objectives Diabetic retinopathy is the main microvascular complication in diabetes mellitus and needs to be diagnosed early to prevent severe sight-threatening retinopathy. The purpose of this study was to quantify the retinal microvasculature pattern and analyze the influence of blood glucose level and the duration of diabetes mellitus on the retinal microvasculature. Methods Two groups were analyzed: patients with diabetes (N=26) and patients without diabetes, ie, controls (N=26). A quantitative semiautomated method analyzed retinal microvasculature. The diameters of arterioles and venules were measured. The total numbers of arterioles and venules were counted. The ratio of arteriole diameter to venule diameter was calculated. The retinal microvasculature pattern was related to clinical and biochemical parameters. Results Patients with diabetes exhibited larger venule diameters in the upper temporal quadrant of the retina compared to the lower temporal quadrant (124.85±38.03 µm vs 102.92±15.69 µm; P<0.01). Patients with diabetes for 5 or more years had larger venule diameters in the upper temporal quadrant than patients without diabetes (141.62±44.44 vs 112.58±32.11 µm; P<0.05). The degree of venodilation in the upper temporal quadrant was positively correlated with blood glucose level and the estimated duration of diabetes mellitus. Interpretation and conclusion The employed quantitative method demonstrated that patients with diabetes exhibited venule dilation in the upper temporal quadrant, and the duration of diabetes mellitus was positively correlated with blood glucose level. Therefore, the early assessment of retinal microvascular changes is possible prior to the onset of diabetic retinopathy. PMID:26345217

  6. Change in intraocular pressure during scleral depression.

    PubMed

    Trevino, Richard; Stewart, Brandi

    2015-01-01

    Manometric studies have found that intraocular pressure (IOP) rises 116-350 mmHg during scleral depression in surgical settings. No information is available regarding the effect of scleral depression on IOP in routine clinical settings. The aim of this study is to quantify the change in IOP that occurs when scleral depression is performed on normal eyes in a routine clinical setting. A total of 28 eyes from 28 normal subjects were included. Tono-Pen tonometry was performed while scleral depression was performed in each of the two quadrants: superotemporal (ST) and inferonasal (IN). A post-procedure IOP measurement was obtained following each scleral depression examination. Both ST and IN quadrants were tested on all eyes, with the quadrant tested first chosen at random (15 ST, 13 IN). The mean IOP during scleral depression was 65.3 mmHg ST and 47.8 mmHg IN, with a maximum recorded IOP of 88 mmHg. The mean change in IOP for the ST quadrant was 51.9 ± 17.3 mmHg and 46.4 ± 16.0 mmHg for the right and left eyes, respectively. The mean change in IOP for the IN quadrant was 45.3 ± 22.7 mmHg and 16.8 ± 15.8 mmHg for the right and left eyes, respectively. Scleral depression as performed in a routine office setting produces wide fluctuations in IOP and may impair ocular perfusion. Additional studies are needed to determine the long-term consequences of routine scleral depression. Copyright © 2014 Spanish General Council of Optometry. Published by Elsevier Espana. All rights reserved.

  7. Feasibility of intraoperative imaging during Mohs surgery with reflectance confocal microscopy

    NASA Astrophysics Data System (ADS)

    Flores, Eileen S.; Cordova, Miguel; Kose, Kivanc; Phillips, William; Nehal, Kishwer; Rajadhyaksha, Milind

    2014-03-01

    Mohs surgery for the removal of non-melanoma skin cancers (NMSCs) is performed in stages, while being guided by the examination for residual tumor with frozen pathology. However, preparation of frozen pathology at each stage is timeconsuming and labor-intensive. Real-time intraoperative reflectance confocal microscopy (RCM) may enable rapid detection of residual tumor directly in surgical wounds on patients. We report initial feasibility on twenty-one patients, using 35% AlCl3 for nuclear contrast. Imaging was performed in quadrants in the wound, to simulate the Mohs surgeon's examination of pathology. Images and videos of the epidermal and dermal margins were found to be of clinically acceptable quality. Bright nuclear morphology was identified at the epidermal margin. The presence of residual BCC/SCC tumor and normal skin features could be detected in the peripheral and deep dermal margins. Nuclear morphology was detectable in residual BCC/SCC tumors. Intraoperative RCM imaging may enable detection of residual tumor, directly on Mohs patients, and may serve as an adjunct for frozen pathology. However, a stronger source of contrast will be necessary, and also a smaller device with an automated approach for imaging in the entire wound in a rapid and controlled manner for clinical utility.

  8. Nanoporous hard data: optical encoding of information within nanoporous anodic alumina photonic crystals

    NASA Astrophysics Data System (ADS)

    Santos, Abel; Law, Cheryl Suwen; Pereira, Taj; Losic, Dusan

    2016-04-01

    Herein, we present a method for storing binary data within the spectral signature of nanoporous anodic alumina photonic crystals. A rationally designed multi-sinusoidal anodisation approach makes it possible to engineer the photonic stop band of nanoporous anodic alumina with precision. As a result, the transmission spectrum of these photonic nanostructures can be engineered to feature well-resolved and selectively positioned characteristic peaks across the UV-visible spectrum. Using this property, we implement an 8-bit binary code and assess the versatility and capability of this system by a series of experiments aiming to encode different information within the nanoporous anodic alumina photonic crystals. The obtained results reveal that the proposed nanosized platform is robust, chemically stable, versatile and has a set of unique properties for data storage, opening new opportunities for developing advanced nanophotonic tools for a wide range of applications, including sensing, photonic tagging, self-reporting drug releasing systems and secure encoding of information.Herein, we present a method for storing binary data within the spectral signature of nanoporous anodic alumina photonic crystals. A rationally designed multi-sinusoidal anodisation approach makes it possible to engineer the photonic stop band of nanoporous anodic alumina with precision. As a result, the transmission spectrum of these photonic nanostructures can be engineered to feature well-resolved and selectively positioned characteristic peaks across the UV-visible spectrum. Using this property, we implement an 8-bit binary code and assess the versatility and capability of this system by a series of experiments aiming to encode different information within the nanoporous anodic alumina photonic crystals. The obtained results reveal that the proposed nanosized platform is robust, chemically stable, versatile and has a set of unique properties for data storage, opening new opportunities for developing advanced nanophotonic tools for a wide range of applications, including sensing, photonic tagging, self-reporting drug releasing systems and secure encoding of information. Electronic supplementary information (ESI) available: Further details about anodisation profiles, SEM cross-section images, digital pictures, transmission spectra, photonic barcodes and ASCII codes of the different NAA photonic crystals fabricated and analysed in our study. See DOI: 10.1039/c6nr01068g

  9. 18 CFR 38.2 - Incorporation by reference of North American Energy Standards Board Wholesale Electric Quadrant...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Wholesale Electric Quadrant, which are incorporated herein by reference: (1) Open Access Same-Time....13, 001-1.0, 001-9.7, 001-14.1.3, and 001-15.1.2); (2) Open Access Same-Time Information Systems... minor corrections applied May 29, 2009 and September 8, 2009); (3) Open Access Same-Time Information...

  10. 18 CFR 38.2 - Incorporation by reference of North American Energy Standards Board Wholesale Electric Quadrant...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Wholesale Electric Quadrant, which are incorporated herein by reference: (1) Open Access Same-Time....13, 001-1.0, 001-9.7, 001-14.1.3, and 001-15.1.2); (2) Open Access Same-Time Information Systems... minor corrections applied May 29, 2009 and September 8, 2009); (3) Open Access Same-Time Information...

  11. 67. Photocopy of Rudder Bearing Quadrant, Skeg and Rudder Stops. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    67. Photocopy of Rudder Bearing Quadrant, Skeg and Rudder Stops. Erie Concrete & Steel Supply Company, Shipbuilding Division, Erie, Pennsylvania. Coast Guard Headquarters Drawing No. 540-WAGL-2200-17 (right side), dated May 1943. Original drawing property of the U.S. Coast Guard. - U.S. Coast Guard Cutter WHITE HEATH, USGS Integrated Support Command Boston, 427 Commercial Street, Boston, Suffolk County, MA

  12. 66. Photocopy of Rudder Bearing Quadrant, Skeg and Rudder Stops. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    66. Photocopy of Rudder Bearing Quadrant, Skeg and Rudder Stops. Erie Concrete & Steel Supply Company, Shipbuilding Division, Erie, Pennsylvania. Coast Guard Headquarters Drawing No. 540-WAGL-2200-17 (left side), dated May 1943. Original drawing property of the U.S. Coast Guard. - U.S. Coast Guard Cutter WHITE HEATH, USGS Integrated Support Command Boston, 427 Commercial Street, Boston, Suffolk County, MA

  13. 18 CFR 38.2 - Incorporation by reference of North American Energy Standards Board Wholesale Electric Quadrant...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ....13, 001-1.0, 001-9.7, 001-14.1.3, and 001-15.1.2); (2) Open Access Same-Time Information Systems... reference of North American Energy Standards Board Wholesale Electric Quadrant standards. 38.2 Section 38.2... UTILITIES § 38.2 Incorporation by reference of North American Energy Standards Board Wholesale Electric...

  14. Commentary--Of Quadrants and Fish Scales: Reflections on New Directions in Research in Child and Adolescent Development

    ERIC Educational Resources Information Center

    Beckmann, Jens F.

    2015-01-01

    In this article, I reflect on how ways of reporting research as well as reviewing and commenting on submitted manuscripts could take new directions to promote progress in the discipline of developmental science. I argue for (a) attitudinal openness toward migratory impulses in relation to Stokes's quadrant model of science, (b) the…

  15. 76 FR 61561 - Airworthiness Directives; The Boeing Company Model 737-600, -700, -700C, -800, -900, and -900ER...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-05

    ... AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Final rule. SUMMARY: We are adopting a new... clearance and any wire bundle damage between wire bundle W443 and the left forward rudder quadrant, followed by adjusting the minimum clearance between the wire bundle and the left forward rudder quadrant, and...

  16. 76 FR 2840 - Airworthiness Directives; The Boeing Company Model 737-600, -700, -700C, -800, -900, and -900ER...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-18

    ...: We propose to adopt a new airworthiness directive (AD) for certain Model 737-600, -700, -700C, -800... and any wire bundle damage between wire bundle W443 and the left forward rudder quadrant, followed by adjusting the minimum clearance between the wire bundle and the left forward rudder quadrant, and repairing...

  17. Concerning the Motion of FTEs and Attendant Signatures

    NASA Technical Reports Server (NTRS)

    Sibeck, David G.

    2010-01-01

    We employ the Cooling et al. [2001] model to predict the location, orientation, and motion of flux transfer events (FTEs) generated along finite length component and anti parallel reconnection lines for typical solar wind plasma conditions and various interplanetary magnetic field (IMF) orientations in the plane perpendicular to the SunEarth line at the solstices and equinoxes. For duskward and northward or southward IMF orientations, events formed by component reconnection originate along reconnection curves passing through the sub solar point that tilt from southern dawn to northern dusk. They maintain this orientation as they move either northward into the northern dawn quadrant or southward into the southern dusk quadrant. By contrast, events formed by antiparallel reconnection originate along reconnection curves running from northern dawn to southern dusk in the southern dawn and northern dusk quadrants and maintain these orientations as they move anti sunward into both these quadrants. Although both the component and antiparallel reconnection models can explain previously reported event orientations on the southern dusk magnetopause during intervals of northward and dawn ward IMF orientation, only the component model explains event occurrence near the subsolar magnetopause during intervals when the IMF does not point due southward.

  18. Array Formatting of the Heat-Transfer Method (HTM) for the Detection of Small Organic Molecules by Molecularly Imprinted Polymers

    PubMed Central

    Wackers, Gideon; Vandenryt, Thijs; Cornelis, Peter; Kellens, Evelien; Thoelen, Ronald; De Ceuninck, Ward; Losada-Pérez, Patricia; van Grinsven, Bart; Peeters, Marloes; Wagner, Patrick

    2014-01-01

    In this work we present the first steps towards a molecularly imprinted polymer (MIP)-based biomimetic sensor array for the detection of small organic molecules via the heat-transfer method (HTM). HTM relies on the change in thermal resistance upon binding of the target molecule to the MIP-type receptor. A flow-through sensor cell was developed, which is segmented into four quadrants with a volume of 2.5 μL each, allowing four measurements to be done simultaneously on a single substrate. Verification measurements were conducted, in which all quadrants received a uniform treatment and all four channels exhibited a similar response. Subsequently, measurements were performed in quadrants, which were functionalized with different MIP particles. Each of these quadrants was exposed to the same buffer solution, spiked with different molecules, according to the MIP under analysis. With the flow cell design we could discriminate between similar small organic molecules and observed no significant cross-selectivity. Therefore, the MIP array sensor platform with HTM as a readout technique, has the potential to become a low-cost analysis tool for bioanalytical applications. PMID:24955945

  19. Image intensification; Proceedings of the Meeting, Los Angeles, CA, Jan. 17, 18, 1989

    NASA Astrophysics Data System (ADS)

    Csorba, Illes P.

    Various papers on image intensification are presented. Individual topics discussed include: status of high-speed optical detector technologies, super second generation imge intensifier, gated image intensifiers and applications, resistive-anode position-sensing photomultiplier tube operational modeling, undersea imaging and target detection with gated image intensifier tubes, image intensifier modules for use with commercially available solid state cameras, specifying the components of an intensified solid state television camera, superconducting IR focal plane arrays, one-inch TV camera tube with very high resolution capacity, CCD-Digicon detector system performance parameters, high-resolution X-ray imaging device, high-output technology microchannel plate, preconditioning of microchannel plate stacks, recent advances in small-pore microchannel plate technology, performance of long-life curved channel microchannel plates, low-noise microchannel plates, development of a quartz envelope heater.

  20. Diagnosis of Upper Quadrant Lymphedema Secondary to Cancer: Clinical Practice Guideline From the Oncology Section of the American Physical Therapy Association

    PubMed Central

    Levenhagen, Kimberly; Davies, Claire; Perdomo, Marisa; Ryans, Kathryn

    2017-01-01

    Abstract The Oncology Section of the American Physical Therapy Association (APTA) developed a clinical practice guideline to aid the clinician in diagnosing secondary upper quadrant cancer-related lymphedema. Following a systematic review of published studies and a structured appraisal process, recommendations were written to guide the physical therapist and other health care clinicians in the diagnostic process. Overall clinical practice recommendations were formulated based on the evidence for each diagnostic method and were assigned a grade based on the strength of the evidence for different patient presentations and clinical utility. In an effort to maximize clinical applicability, recommendations were based on the characteristics as to the location and stage of a patient's upper quadrant lymphedema. PMID:28838217

  1. Reliability testing of ultra-low noise InGaAs quad photoreceivers

    NASA Astrophysics Data System (ADS)

    Joshi, Abhay M.; Datta, Shubhashish; Prasad, Narasimha; Sivertz, Michael

    2018-02-01

    We have developed ultra-low noise quadrant InGaAs photoreceivers for multiple applications ranging from Laser Interferometric Gravitional Wave Detection, to 3D Wind Profiling. Devices with diameters of 0.5 mm, 1mm, and 2 mm were processed, with the nominal capacitance of a single quadrant of a 1 mm quad photodiode being 2.5 pF. The 1 mm diameter InGaAs quad photoreceivers, using a low-noise, bipolar-input OpAmp circuitry exhibit an equivalent input noise per quadrant of <1.7 pA/√Hz in 2 to 20 MHz frequency range. The InGaAs Quad Photoreceivers have undergone the following reliability tests: 30 MeV Proton Radiation up to a Total Ionizing Dose (TID) of 50 krad, Mechanical Shock, and Sinusoidal Vibration.

  2. Structurally tailored graphene nanosheets as lithium ion battery anodes: an insight to yield exceptionally high lithium storage performance

    NASA Astrophysics Data System (ADS)

    Li, Xifei; Hu, Yuhai; Liu, Jian; Lushington, Andrew; Li, Ruying; Sun, Xueliang

    2013-11-01

    How to tune graphene nanosheets (GNSs) with various morphologies has been a significant challenge for lithium ion batteries (LIBs). In this study, three types of GNSs with varying size, edge sites, defects and layer numbers have been successfully achieved. It was demonstrated that controlling GNS morphology and microstructure has important effects on its cyclic performance and rate capability in LIBs. Diminished GNS layer number, decreased size, increased edge sites and increased defects in the GNS anode can be highly beneficial to lithium storage and result in increased electrochemical performance. Interestingly, GNSs treated with a hydrothermal approach delivered a high reversible discharge capacity of 1348 mA h g-1. This study demonstrates that the controlled design of high performance GNS anodes is an important concept in LIB applications.How to tune graphene nanosheets (GNSs) with various morphologies has been a significant challenge for lithium ion batteries (LIBs). In this study, three types of GNSs with varying size, edge sites, defects and layer numbers have been successfully achieved. It was demonstrated that controlling GNS morphology and microstructure has important effects on its cyclic performance and rate capability in LIBs. Diminished GNS layer number, decreased size, increased edge sites and increased defects in the GNS anode can be highly beneficial to lithium storage and result in increased electrochemical performance. Interestingly, GNSs treated with a hydrothermal approach delivered a high reversible discharge capacity of 1348 mA h g-1. This study demonstrates that the controlled design of high performance GNS anodes is an important concept in LIB applications. Electronic supplementary information (ESI) available: SEM morphologies of GNS-I-III at low magnification, the TEM image of GNSs hydrothermally treated with urea in a ratio of 1 : 0, XPS survey, and SEM morphology changes of the three GNS anodes at low magnification after 100 charge-discharge cycles. See DOI: 10.1039/c3nr04823c

  3. Multi-anode microchannel arrays. [for use in ground-based and spaceborne telescopes

    NASA Technical Reports Server (NTRS)

    Timothy, J. G.; Mount, G. H.; Bybee, R. L.

    1979-01-01

    The Multi-Anode Microchannel Arrays (MAMA's) are a family of photoelectric, photon-counting array detectors being developed for use in instruments on both ground-based and space-borne telescopes. These detectors combine high sensitivity and photometric stability with a high-resolution imaging capability. MAMA detectors can be operated in a windowless configuration at extreme-ultraviolet and soft X-ray wavelengths or in a sealed configuration at ultraviolet and visible wavelengths. Prototype MAMA detectors with up to 512 x 512 pixels are now being tested in the laboratory and telescope operation of a simple (10 x 10)-pixel visible-light detector has been initiated. The construction and modes-of-operation of the MAMA detectors are briefly described and performance data are presented.

  4. Ground-Support Algorithms for Simulation, Processing, and Calibration of Barnes Static Earth Sensor Measurements: Applications to Tropical Rainfall Measuring Mission Observatory

    NASA Technical Reports Server (NTRS)

    Natanson, G. A.

    1997-01-01

    New algorithms are described covering the simulation, processing, and calibration of penetration angles of the Barnes static Earth sensor assembly (SESA) as implemented in the Goddard Space Flight Center Flight Dynamics Division ground support system for the Tropical Rainfall Measuring Mission (TRMM) Observatory. The new treatment involves a detailed analysis of the measurements by individual quadrants. It is shown that, to a good approximation, individual quadrant misalignments can be treated simply as penetration angle biases. Simple formulas suitable for real-time applications are introduced for computing quadrant-dependent effects. The simulator generates penetration angles by solving a quadratic equation with coefficients uniquely determined by the spacecraft's position and the quadrant's orientation in GeoCentric Inertial (GCI) coordinates. Measurement processing for attitude determination is based on linearized equations obtained by expanding the coefficients of the aforementioned quadratic equation as a Taylor series in both the Earth oblateness coefficient (alpha approx. 1/150) and the angle between the pointing axis and the geodetic nadir vector. A simple formula relating a measured value of the penetration angle to the deviation of the Earth-pointed axis from the geodetic nadir vector is derived. It is shown that even near the very edge of the quadrant's Field Of View (FOV), attitude errors resulting from quadratic effects are a few hundredths of a degree, which is small compared to the attitude determination accuracy requirement (0.18 degree, 3 sigma) of TRMM. Calibration of SESA measurements is complicated by a first-order filtering used in the TRMM onboard algorithm to compute penetration angles from raw voltages. A simple calibration scheme is introduced where these complications are avoided by treating penetration angles as the primary raw measurements, which are adjusted using biases and scale factors. In addition to three misalignment parameters, the calibration state vector contains only two average penetration angle biases (one per each pair of opposite quadrants) since, because of the very narrow sensor FOV (+/- 2.6 degrees), differences between biases of the penetration angles measured by opposite quadrants cannot be distinguished from roll and pitch sensor misalignments. After calibration, the estimated misalignments and average penetration angle biases are converted to the four penetration angle biases and to the yaw misalignment angle. The resultant biases and the estimated scale factors are finally used to update the coefficients necessary for onboard computations of penetration angles from measured voltages.

  5. Design Method of Digital Optimal Control Scheme and Multiple Paralleled Bridge Type Current Amplifier for Generating Gradient Magnetic Fields in MRI Systems

    NASA Astrophysics Data System (ADS)

    Watanabe, Shuji; Takano, Hiroshi; Fukuda, Hiroya; Hiraki, Eiji; Nakaoka, Mutsuo

    This paper deals with a digital control scheme of multiple paralleled high frequency switching current amplifier with four-quadrant chopper for generating gradient magnetic fields in MRI (Magnetic Resonance Imaging) systems. In order to track high precise current pattern in Gradient Coils (GC), the proposal current amplifier cancels the switching current ripples in GC with each other and designed optimum switching gate pulse patterns without influences of the large filter current ripple amplitude. The optimal control implementation and the linear control theory in GC current amplifiers have affinity to each other with excellent characteristics. The digital control system can be realized easily through the digital control implementation, DSPs or microprocessors. Multiple-parallel operational microprocessors realize two or higher paralleled GC current pattern tracking amplifier with optimal control design and excellent results are given for improving the image quality of MRI systems.

  6. Finding of biliary fascioliasis by endoscopic ultrasonography in a patient with eosinophilic liver abscess.

    PubMed

    Behzad, Catherine; Lahmi, Farhad; Iranshahi, Majid; Mohammad Alizadeh, Amir Houshang

    2014-09-01

    Fascioliasis is an endemic zoonotic disease in Iran. It occurs mainly in sheep-rearing areas of temperate climates, but sporadic cases have been reported from many other parts of the world. The usual definitive host is the sheep. Humans are accidental hosts in the life cycle of Fasciola. Typical symptoms may be associated with fascioliasis, but in some cases diagnosis and treatment may be preceded by a long period of abdominal pain and vague gastrointestinal symptoms. We report a case with epigastric and upper quadrant abdominal pain for the last 6 months, with imaging suggesting liver abscess and normal biliary ducts. The patient had no eosinophilia with negative stool examinations, so she was initially treated with antibiotics for liver abscess. Her clinical condition as well as follow-up imagings showed appropriate response after antibiotic therapy. Finally, endoscopic ultrasonography revealed Fasciola hepatica, which was then extracted with endoscopic retrograde cholangiopancreatography.

  7. Fabrication of free-standing copper foils covered with highly-ordered copper nanowire arrays

    NASA Astrophysics Data System (ADS)

    Zaraska, Leszek; Sulka, Grzegorz D.; Jaskuła, Marian

    2012-07-01

    The through-hole nanoporous anodic aluminum oxide (AAO) membranes with relatively large surface area (ca. 2 cm2) were employed for fabrication of free-standing and mechanically stable copper foils covered with close-packed and highly-ordered copper nanowire arrays. The home-made AAO membranes with different pore diameters and interpore distances were fabricated via a two-step self-organized anodization of aluminum performed in sulfuric acid, oxalic acid and phosphoric acid followed by the pore opening/widening procedure. The direct current (DC) electrodeposition of copper was performed efficiently on both sides of AAO templates. The bottom side of the AAO templates was not insulated and consequently Cu nanowire arrays on thick Cu layers were obtained. The proposed template-assisted fabrication of free-standing copper nanowire array electrodes is a promising method for synthesis of nanostructured current collectors. The composition of Cu nanowires was confirmed by energy dispersive X-Ray spectroscopy (EDS) and X-ray diffraction (XRD) analyses. The structural features of nanowires were evaluated from field emission scanning electron microscopy (FE-SEM) images and compared with the characteristic parameters of anodic alumina membranes.

  8. The effect of fluoroethylene carbonate additive content on the formation of the solid-electrolyte interphase and capacity fade of Li-ion full-cell employing nano Si-graphene composite anodes

    NASA Astrophysics Data System (ADS)

    Bordes, Arnaud; Eom, KwangSup; Fuller, Thomas F.

    2014-07-01

    When fluoroethylene carbonate (FEC) is added to the ethylene carbonate (EC)-diethyl carbonate (DEC) electrolyte, the capacity and cyclability of full-cells employing Si-graphene anode and lithium nickel cobalt aluminum oxide cathode (NCA) cathode are improved due to formation of a thin (30-50 nm) SEI layer with low ionic resistance (∼2 ohm cm2) on the surface of Si-graphene anode. These properties are confirmed with electrochemical impedance spectroscopy and a cross-sectional image analysis using Focused Ion Beam (FIB)-SEM. Approximately 5 wt.% FEC in EC:DEC (1:1 wt.%) shows the highest capacity and most stability. This high capacity and low capacity fade is attributed to a more stable SEI layer containing less CH2OCO2Li, Li2CO3 and LiF compounds, which consume cyclable Li. Additionally, a greater amount of polycarbonate (PC), which is known to form a more robust passivation layer, thus reducing further reduction of electrolyte, is confirmed with X-ray photoelectron spectroscopy (XPS).

  9. Understanding the crack formation of graphite particles in cycled commercial lithium-ion batteries by focused ion beam - scanning electron microscopy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lin, Na; Jia, Zhe; Wang, Zhihui

    Here in this paper, the structure degradation of commercial Lithium-ion battery (LIB) graphite anodes with different cycling numbers and charge rates was investigated by focused ion beam (FIB) and scanning electron microscopy (SEM). The cross-section image of graphite anode by FIB milling shows that cracks, resulted in the volume expansion of graphite electrode during long-term cycling, were formed in parallel with the current collector. The crack occurs in the bulk of graphite particles near the lithium insertion surface, which might derive from the stress induced during lithiation and de-lithiation cycles. Subsequently, crack takes place along grain boundaries of the polycrystallinemore » graphite, but only in the direction parallel with the current collector. Furthermore, fast charge graphite electrodes are more prone to form cracks since the tensile strength of graphite is more likely to be surpassed at higher charge rates. Therefore, for LIBs long-term or high charge rate applications, the tensile strength of graphite anode should be taken into account.« less

  10. Understanding the crack formation of graphite particles in cycled commercial lithium-ion batteries by focused ion beam - scanning electron microscopy

    DOE PAGES

    Lin, Na; Jia, Zhe; Wang, Zhihui; ...

    2017-10-01

    Here in this paper, the structure degradation of commercial Lithium-ion battery (LIB) graphite anodes with different cycling numbers and charge rates was investigated by focused ion beam (FIB) and scanning electron microscopy (SEM). The cross-section image of graphite anode by FIB milling shows that cracks, resulted in the volume expansion of graphite electrode during long-term cycling, were formed in parallel with the current collector. The crack occurs in the bulk of graphite particles near the lithium insertion surface, which might derive from the stress induced during lithiation and de-lithiation cycles. Subsequently, crack takes place along grain boundaries of the polycrystallinemore » graphite, but only in the direction parallel with the current collector. Furthermore, fast charge graphite electrodes are more prone to form cracks since the tensile strength of graphite is more likely to be surpassed at higher charge rates. Therefore, for LIBs long-term or high charge rate applications, the tensile strength of graphite anode should be taken into account.« less

  11. A cometary ion mass spectrometer

    NASA Technical Reports Server (NTRS)

    Shelley, E. G.; Simpson, D. A.

    1984-01-01

    The development of flight suitable analyzer units for that part of the GIOTTO Ion Mass Spectrometer (IMS) experiment designated the High Energy Range Spectrometer (HERS) is discussed. Topics covered include: design of the total ion-optical system for the HERS analyzer; the preparation of the design of analyzing magnet; the evaluation of microchannel plate detectors and associated two-dimensional anode arrays; and the fabrication and evaluation of two flight-suitable units of the complete ion-optical analyzer system including two-dimensional imaging detectors and associated image encoding electronics.

  12. Negative surface streamers propagating on TiO2 and γ-Al2O3-supported Ag catalysts: ICCD imaging and modeling study

    NASA Astrophysics Data System (ADS)

    Kim, Hyun-Ha; Teramoto, Yoshiyuki; Ogata, Atsushi; Kang, Woo Seok; Hur, Min; Song, Young-Hoon

    2018-06-01

    Surface streamers propagating on the surface of titanium dioxide (TiO2) and alumina (γ-Al2O3) were studied in negative polarity using intensified charge coupled device (ICCD) imaging and numerical simulation. Detailed time-resolved ICCD images of cathode-directed streamers (CDSs) emanating from a ground electrode are first presented in this report. Instead of primary streamers in positive polarity, only a glow-like discharge appeared in the early stage at the cathode under negative polarity. After this discharge disappeared, a counter-propagating CDS initiated from the ground electrode (anode). Numerical simulation indicated that strong electric fields at the pellet-anode and the formation of positive ion rich local spots were the main reason for the CDS formation near the ground electrode. The maximum velocity was 750 km s‑1 for Ag-supported γ-Al2O3 and 550 km s‑1 for Ag-supported TiO2, respectively. In contrast to the CDS in the gas-phase with a positive polarity, the CDS in a catalyst packed-bed under negative polarity showed more branching and a larger number of streamers in the presence of oxygen than in pure N2.

  13. Solid State Research

    DTIC Science & Technology

    1990-05-15

    reference to indicate the exact time of the transmitted pulse. The returned pulses are detected using a four - quadrant photomultiplie tube, and each quadrant ...1990) Nondegencrate Four -Wave Mixing K.B. Nichols DTIC AD-A221419 in AlGaAs Waveguides W.D. Goodhue Wafer Fusion: A Novel Technique Z.L. Liau Appl...Annealing H.J. Zeiger (1990) of Etched Compound Semiconductor Structures: Theoretical Modeling and Experimental Confirmation Programmable, Four -Channel

  14. ETR, TRA642. BASEMENT SPACE ALLOCATION FOR EXPERIMENTERS CA. 1966, SOUTHEAST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    ETR, TRA-642. BASEMENT SPACE ALLOCATION FOR EXPERIMENTERS CA. 1966, SOUTHEAST QUADRANT OF FLOOR. WESTINGHOUSE ATOMIC POWER DIVISION (WAPD) AND BETTIS ATOMIC POWER LABORATORY (BAPL) CONSUME MOST OF THE QUADRANT. PHILLIPS PETROLEUM COMPANY ETR-E-2256, 12/1966. INL INDEX NO. 532-0642-00-706-021256, REV. F. - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

  15. Investigating a Quadrant Surface Coil Array for NQR Remote Sensing

    DTIC Science & Technology

    2014-10-23

    UNCLASSIFIED 1  Abstract—this paper is on the design and fabrication of a surface coil array in a quadrant layout for NQR (Nuclear Quadrupole...coupling and SNR (Signal-to-Noise Ratio) at standoff distances perpendicular from each coil. Index Terms— Nuclear Quadrupole Resonance, NQR ...Coil Array, probe, Nuclear Magnetic Resonance, tuning, decoupling, RLC, mutual coupling, RLC I. INTRODUCTION N Nuclear quadrupole resonance ( NQR

  16. Vertical integration of array-type miniature interferometers at wafer level by using multistack anodic bonding

    NASA Astrophysics Data System (ADS)

    Wang, Wei-Shan; Wiemer, Maik; Froemel, Joerg; Enderlein, Tom; Gessner, Thomas; Lullin, Justine; Bargiel, Sylwester; Passilly, Nicolas; Albero, Jorge; Gorecki, Christophe

    2016-04-01

    In this work, vertical integration of miniaturized array-type Mirau interferometers at wafer level by using multi-stack anodic bonding is presented. Mirau interferometer is suitable for MEMS metrology and for medical imaging according to its vertical-, lateral- resolutions and working distances. Miniaturized Mirau interferometer can be a promising candidate as a key component of an optical coherence tomography (OCT) system. The miniaturized array-type interferometer consists of a microlens doublet, a Si-based MEMS Z scanner, a spacer for focus-adjustment and a beam splitter. Therefore, bonding technologies which are suitable for heterogeneous substrates are of high interest and necessary for the integration of MEMS/MOEMS devices. Multi-stack anodic bonding, which meets the optical and mechanical requirements of the MOEMS device, is adopted to integrate the array-type interferometers. First, the spacer and the beam splitter are bonded, followed by bonding of the MEMS Z scanner. In the meanwhile, two microlenses, which are composed of Si and glass wafers, are anodically bonded to form a microlens doublet. Then, the microlens doublet is aligned and bonded with the scanner/spacer/beam splitter stack. The bonded array-type interferometer is a 7- wafer stack and the thickness is approximately 5mm. To separate such a thick wafer stack with various substrates, 2-step laser cutting is used to dice the bonded stack into Mirau chips. To simplify fabrication process of each component, electrical connections are created at the last step by mounting a Mirau chip onto a flip chip PCB instead of through wafer vias. Stability of Au/Ti films on the MEMS Z scanner after anodic bonding, laser cutting and flip chip bonding are discussed as well.

  17. Closed bore XMR (CBXMR) systems for aortic valve replacement: Investigation of rotating-anode x-ray tube heat loadability

    PubMed Central

    Bracken, John A.; Lillaney, Prasheel V.; Fahrig, Rebecca; Rowlands, J. A.

    2008-01-01

    In order to improve the safety and efficacy of percutaneous aortic valve replacement procedures, a closed bore hybrid x-ray∕MRI (CBXMR) system is proposed in which an x-ray C-arm will be positioned with its isocenter ≈1 m from the entrance of a clinical MRI scanner. This system will harness the complementary strengths of both modalities to improve clinical outcome. A key component of the CBXMR system will be a rotating anode x-ray tube to produce high-quality x-ray images. There are challenges in positioning an x-ray tube in the magnetic fringe field of the MRI magnet. Here, the effects of an external magnetic field on x-ray tube induction motors of radiography x-ray tubes and the corresponding reduction of x-ray tube heat loadability are investigated. Anode rotation frequency fanode was unaffected when the external magnetic field Bb was parallel to the axis of rotation of the anode but decreased when Bb was perpendicular to the axis of rotation. The experimental fanode values agreed with predicted values to within ±3% over a Bb range of 0–30 mT. The MRI fringe field at the proposed location of the x-ray tube mounted on the C-arm (≈4 mT) reduced fanode by only 1%, so x-ray tube heat loadability will not be compromised when using CBXMR systems for percutaneous aortic valve replacement procedures. Eddy current heating power in the rotor due to an MRI fringe field was found to be two orders of magnitude weaker than the heating power produced on the anode due to a fluoroscopic exposure, so eddy current heating had no effect on x-ray tube heat loadability. PMID:18841857

  18. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lillaney, Prasheel; Pelc, Norbert; Shin Mihye

    Purpose: Using hybrid x-ray/MR (XMR) systems for image guidance during interventional procedures could enhance the diagnosis and treatment of neurologic, oncologic, cardiovascular, and other disorders. The authors propose a close proximity hybrid system design in which a C-arm fluoroscopy unit is placed immediately adjacent to the solenoid magnet of a MR system with a minimum distance of 1.2 m between the x-ray and MR imaging fields of view. Existing rotating anode x-ray tube designs fail within MR fringe field environments because the magnetic fields alter the electron trajectories in the x-ray tube and act as a brake on the inductionmore » motor, reducing the rotation speed of the anode. In this study the authors propose a novel motor design that avoids the anode rotation speed reduction. Methods: The proposed design replaces the permanent magnet stator found in brushed dc motors with the radial component of the MR fringe field. The x-ray tube is oriented such that the radial component of the MR fringe field is orthogonal to the cathode-anode axis. Using a feedback position sensor and the support bearings as electrical slip rings, the authors use electrical commutation to eliminate the need for mechanical brushes and commutators. A vacuum compatible prototype of the proposed motor design was assembled, and its performance was evaluated at various operating conditions. The prototype consisted of a 3.1 in. diameter anode rated at 300 kHU with a ceramic rotor that was 5.6 in. in length and had a 2.9 in. diameter. The material chosen for all ceramic components was MACOR, a machineable glass ceramic developed by Corning Inc. The approximate weight of the entire assembly was 1750 g. The maximum rotation speed, angular acceleration, and acceleration time of the motor design were investigated, as well as the dependence of these parameters on rotor angular offset, magnetic field strength, and field orientation. The resonance properties of the authors' assembly were also evaluated to determine its stability during acceleration, and a pulse width modulation algorithm was implemented to control the rotation speed of the motor. Results: At a magnetic flux density of 41 mT orthogonal to the axis of rotation (on the lower end of the expected flux density in the MR suite) the maximum speed of the motor was found to be 5150 revolutions per minute (rpm). The acceleration time necessary to reach 3000 rpm was found to be approximately 10 s at 59 mT. The resonance frequency of the assembly with the anode attached was 1310 rpm (21.8 Hz) which is far below the desired operating speeds. Pulse width modulation provides an effective method to control the speed of the motor with a resolution of 100 rpm. Conclusions: The proposed design can serve as a direct replacement to the conventional induction motor used in rotating anode x-ray tubes. It does not suffer from a reduced rotation speed when operating in a MR environment. The presence of chromic steel bearings in the prototype prevented testing at the higher field strengths, and future iterations of the design could eliminate this shortcoming. The prototype assembly demonstrates proof of concept of the authors' design and overcomes one of the major obstacles for a MR compatible rotating anode x-ray tube.« less

  19. Generation and analysis of clinically relevant breast imaging x-ray spectra.

    PubMed

    Hernandez, Andrew M; Seibert, J Anthony; Nosratieh, Anita; Boone, John M

    2017-06-01

    The purpose of this work was to develop and make available x-ray spectra for some of the most widely used digital mammography (DM), breast tomosynthesis (BT), and breast CT (bCT) systems in North America. The Monte Carlo code MCNP6 was used to simulate minimally filtered (only beryllium) x-ray spectra at 8 tube potentials from 20 to 49 kV for DM/BT, and 9 tube potentials from 35 to 70 kV for bCT. Vendor-specific anode compositions, effective anode angles, focal spot sizes, source-to-detector distances, and beryllium filtration were simulated. For each 0.5 keV energy bin in all simulated spectra, the fluence was interpolated using cubic splines across the range of simulated tube potentials to produce spectra in 1 kV increments from 20 to 49 kV for DM/BT and from 35 to 70 kV for bCT. The HVL of simulated spectra with conventional filtration (at 35 kV for DM/BT and 49 kV for bCT) was used to assess spectral differences resulting from variations in: (a) focal spot size (0.1 and 0.3 mm IEC), (b) solid angle at the detector (i.e., small and large FOV size), and (c) geometrical specifications for vendors that employ the same anode composition. Averaged across all DM/BT vendors, variations in focal spot and FOV size resulted in HVL differences of 2.2% and 0.9%, respectively. Comparing anode compositions separately, the HVL differences for Mo (GE, Siemens) and W (Hologic, Philips, and Siemens) spectra were 0.3% and 0.6%, respectively. Both the commercial Koning and prototype "Doheny" (UC Davis) bCT systems utilize W anodes with a 0.3 mm focal spot. Averaged across both bCT systems, variations in FOV size resulted in a 2.2% difference in HVL. In addition, the Koning spectrum was slightly harder than Doheny with a 4.2% difference in HVL. Therefore to reduce redundancy, a generic DM/BT system and a generic bCT system were used to generate the new spectra reported herein. The spectral models for application to DM/BT were dubbed the Molybdenum, Rhodium, and Tungsten Anode Spectral Models using Interpolating Cubic Splines (MASMICS M -T , RASMICS M-T , and TASMICS M-T ; subscript "M-T" indicating mammography and tomosynthesis). When compared against reference models (MASMIP M , RASMIP M , and TASMIP M ; subscript "M" indicating mammography), the new spectral models were in close agreement with mean differences of 1.3%, -1.3%, and -3.3%, respectively, across tube potential comparisons of 20, 30, and 40 kV with conventional filtration. TASMICS b CT -generated bCT spectra were also in close agreement with the reference TASMIP model with a mean difference of -0.8%, across tube potential comparisons of 35, 49, and 70 kV with 1.5 mm Al filtration. The Mo, Rh, and W anode spectra for application in DM and BT (MASMICS M-T , RASMICS M-T , and TASMICS M-T ) and the W anode spectra for bCT (TASMICS bCT ) as described in this study should be useful for individuals interested in modeling the performance of modern breast x-ray imaging systems including dual-energy mammography which extends to 49 kV. These new spectra are tabulated in spreadsheet form and are made available to any interested party. © 2017 American Association of Physicists in Medicine.

  20. Application of a computed tomography based cystic fibrosis scoring system to chest tomosynthesis

    NASA Astrophysics Data System (ADS)

    Söderman, Christina; Johnsson, Åse; Vikgren, Jenny; Rystedt, Hans; Ivarsson, Jonas; Rossi Norrlund, Rauni; Nyberg Andersson, Lena; Bâth, Magnus

    2013-03-01

    In the monitoring of progression of lung disease in patients with cystic fibrosis (CF), recurrent computed tomography (CT) examinations are often used. The relatively new imaging technique chest tomosynthesis (CTS) may be an interesting alternative in the follow-up of these patients due to its visualization of the chest in slices at radiation doses and costs significantly lower than is the case with CT. A first step towards introducing CTS imaging in the diagnostics of CF patients is to establish a scoring system appropriate for evaluating the severity of CF pulmonary disease based on findings in CTS images. Previously, several such CF scoring systems based on CT imaging have been published. The purpose of the present study was to develop a CF scoring system for CTS, by starting from an existing scoring system dedicated for CT images and making modifications regarded necessary to make it appropriate for use with CTS images. In order to determine any necessary changes, three thoracic radiologists independently used a scoring system dedicated for CT on both CT and CTS images from CF patients. The results of the scoring were jointly evaluated by all the observers, which lead to suggestions for changes to the scoring system. Suggested modifications include excluding the scoring of air trapping and doing the scoring of the findings in quadrants of the image instead of in each lung lobe.

  1. Partial-mouth periodontal examination protocols for the determination of the prevalence and extent of gingival bleeding in adolescents.

    PubMed

    Machado, Michely Ediani; Tomazoni, Fernanda; Casarin, Maísa; Ardenghi, Thiago M; Zanatta, Fabricio Batistin

    2017-10-01

    To compare the performance of partial-mouth periodontal examination (PMPE) protocols with different cut-off points to the full-mouth examination (FME) in the assessment of the prevalence and extent of gingival bleeding in adolescents. A cross-sectional study was conducted involving 12-year-old adolescents. Following a systematic two-stage cluster sampling process, 1134 individuals were evaluated. Different PMPE protocols were compared to the FME with six sites per tooth. Sensitivity, specificity, area under the ROC curve (AUC), intraclass correlation coefficient (ICC), relative and absolute biases and the inflation factor were assessed for each PMPE protocol with different cut-off points for the severity of gingival bleeding. The highest AUC values were found for the six-site two-diagonal quadrant (2-4) (0.97), six-site random half-mouth (0.95) and Community Periodontal Index (0.95) protocols. The assessment of three sites [mesiobuccal (MB), buccal (B) and distolingual (DL)] in two diagonal quadrants and the random half-mouth protocol had higher sensitivity and lower specificity than the same protocols with distobuccal (DB) sites. However, the use of DB sites led to better specificity and improved the balance between sensitivity and specificity, except for the two-diagonal quadrant (1-3) protocol. The ≥1 cut-off point led to the most discrepant results from the FME. Six-site two-diagonal quadrant (2-4) and random half-mouth assessments perform better in the evaluation of gingival bleeding in adolescents. However, when a faster protocol is needed, a two-diagonal quadrant assessment using only MB, B and DL sites can be used with no important loss of information. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  2. Optical coherence tomography in papilledema and pseudopapilledema with and without optic nerve head drusen

    PubMed Central

    Bassi, Shikha Talwar; Mohana, Kuppuswamy Parthasarthy

    2014-01-01

    Aim: To compare the spectral domain optical coherence tomography (SD-OCT) findings of the optic disc and the peripapillary retina of patients with a true papilledema and pseudopapilledema with and without optic nerve head drusen (ONHD). Study Design: Retrospective Case Control Study. Subjects and Methods: Peripapillary retinal nerve fiber layer (PPRNFL) thickness as depicted by SD-OCT of 94 eyes of 66 patients with papilledema (30 eyes), pseudopapiledema (31 eyes), and normal controls (33 eyes) was analyzed. The mean RNFL thickness, total retinal thickness (TRT) at a superior and inferior edge of the disc and the quadrant wise topography of increased RNFL were compared in all three groups. Sensitivity, specificity, and area under the receiver operating characteristic curve (AROC) were calculated for all the parameters. Results: The median RNFL thickness was 185.4 (129.5–349.3 μm), 122.3 (109–156.3 μm) and 91.62 ± 7 μm in papilledema, pseudopapilledema, and controls, respectively. Papilledema group had thicker PPRNFL in all quadrants except temporal quadrant. TRT was thicker in papilledema and pseudopapilledema compared to controls. ONHD could be directly visualized as high reflective clumps in the sub-retinal space or the RNFL in 30 eyes. Increased RNFL thickness in all four quadrants was noted 43.3% in papilledema and 9.7% in pseudopapilledema. Normal RNFL thickness in all four quadrants was noted in 0% in papilledema and 32.3% in pseudopapilledema. Nasal RNFL had the highest AROC (0.792) indicating high diagnostic ability to differentiate papilledema from pseudopapilledema. Conclusion: SD-OCT can be used as a tool to differentiate between papilledema and pseudopapilledema. PMID:25579359

  3. Retinal Nerve Fiber Layer Thickness Changes in the Pseudoexfoliation Syndrome: A Meta-Analysis of Case-Control Studies.

    PubMed

    Yu, Ji-Guo; Huang, Qing; Zhou, Xiao-Fang; Ding, Yi; Li, Jing; Xiang, Yi

    2018-01-01

    To evaluate and compare changes in retinal nerve fiber layer (RNFL) thickness in patients with the pseudoexfoliation syndrome (PXS) and healthy controls. Case-control studies were selected through an electronic search of the Cochrane Controlled Trials Register, PubMed, and Embase. Results were reviewed to ensure that the included studies met prespecified inclusion/exclusion criteria, and the quality of each study was assessed using the Newcastle-Ottawa Scale. All included studies measured average and 4-quadrant (temporal, superior, nasal, and inferior) RNFL thickness using optical coherence tomography (OCT). For the continuous outcomes, we calculated the weighted mean difference (WMD) and 95% confidence intervals (CIs). Eight case-control studies were included in this meta-analysis involving 225 eyes of PXS patients and 208 eyes of healthy controls in total. Statistical analysis revealed that the average RNFL thickness in PXS patients was significantly reduced compared to healthy controls (WMD = -6.91, 95% CI: -9.99 to -3.82, p < 0.0001). Additionally, differences in RNFL thickness in the superior quadrant (WMD = -10.68, 95% CI: -16.40 to -4.95, p = 0.0003), inferior quadrant (WMD = -8.20, 95% CI: -10.85 to -5.55, p < 0.00001), nasal quadrant (WMD = -3.05, 95% CI: -5.21 to -0.90, p = 0.005), and temporal quadrant (WMD = -6.39, 95% CI: -9.98 to -2.80, p = 0.0005) were all significant between the two groups. These results suggest that it is important to evaluate RNFL thickness and the optic nerve head through OCT in patients with PXS in order to determine early glaucomatous damage and start timely intervention prior to visual field loss. © 2017 S. Karger AG, Basel.

  4. Two-speed phacoemulsification for soft cataracts using optimized parameters and procedure step toolbar with the CENTURION Vision System and Balanced Tip.

    PubMed

    Davison, James A

    2015-01-01

    To present a cause of posterior capsule aspiration and a technique using optimized parameters to prevent it from happening when operating soft cataracts. A prospective list of posterior capsule aspiration cases was kept over 4,062 consecutive cases operated with the Alcon CENTURION machine and Balanced Tip. Video analysis of one case of posterior capsule aspiration was accomplished. A surgical technique was developed using empirically derived machine parameters and customized setting-selection procedure step toolbar to reduce the pace of aspiration of soft nuclear quadrants in order to prevent capsule aspiration. Two cases out of 3,238 experienced posterior capsule aspiration before use of the soft quadrant technique. Video analysis showed an attractive vortex effect with capsule aspiration occurring in 1/5 of a second. A soft quadrant removal setting was empirically derived which had a slower pace and seemed more controlled with no capsule aspiration occurring in the subsequent 824 cases. The setting featured simultaneous linear control from zero to preset maximums for: aspiration flow, 20 mL/min; and vacuum, 400 mmHg, with the addition of torsional tip amplitude up to 20% after the fluidic maximums were achieved. A new setting selection procedure step toolbar was created to increase intraoperative flexibility by providing instantaneous shifting between the soft and normal settings. A technique incorporating a reduced pace for soft quadrant acquisition and aspiration can be accomplished through the use of a dedicated setting of integrated machine parameters. Toolbar placement of the procedure button next to the normal setting procedure button provides the opportunity to instantaneously alternate between the two settings. Simultaneous surgeon control over vacuum, aspiration flow, and torsional tip motion may make removal of soft nuclear quadrants more efficient and safer.

  5. Evaluation of blotchy pigments in the anterior chamber angle as a sign of angle closure

    PubMed Central

    Rao, Harsha L; Mungale, Sachin C; Kumbar, Tukaram; Parikh, Rajul S; Garudadri, Chandra S

    2012-01-01

    Background: Blotchy pigments in the anterior chamber (AC) angle are considered diagnostic of primary angle closure (PAC). But there are no reports either on the prevalence of blotchy pigments in AC angles or the validity of this sign. Aims: To determine the prevalence of blotchy pigments in AC angles and to evaluate their relationship with glaucomatous optic neuropathy (GON) in eyes with occludable angles. Setting and Design: Cross-sectional, comparative study. Materials and Methods: Gonioscopy was performed in 1001 eyes of 526 subjects (245 eyes of 148 consecutive, occludable angle subjects and 756 eyes of 378 non-consecutive, open angle subjects), above 35 years of age. Quadrant-wise location of blotchy pigments was documented. Statistical Analysis: Odds of blotchy pigments in occludable angles against that in open angles were evaluated. Relationship of GON with blotchy pigments in occludable angle eyes was evaluated using a multivariate model. Results: Prevalence of blotchy pigments in occludable angles was 28.6% (95% CI, 22.9-34.3) and in open angles was 4.7% (95% CI, 3.2-6.3). Blotchy pigments were more frequently seen in inferior (16%) and superior quadrants (15%) of occludable angles, and inferior quadrant of open angles (4%). Odds of superior quadrant blotchy pigments in occludable angles were 33 times that in open angles. GON was seen in 107 occludable angle eyes. Blotchy pigments were not significantly associated with GON (odds ratio = 0.5; P = 0.1). Conclusions: Blotchy pigments were seen in 28.6% of occludable angle eyes and 4.7% of open angles eyes. Presence of blotchy pigments in the superior quadrant is more common in occludable angles. Presence of GON in occludable angle eyes was not associated with blotchy pigments. PMID:23202393

  6. Prevailing surface winds in Northern Serbia in the recent and past time periods; modern- and past dust deposition

    NASA Astrophysics Data System (ADS)

    Gavrilov, Milivoj B.; Marković, Slobodan B.; Schaetzl, Randall J.; Tošić, Ivana; Zeeden, Christian; Obreht, Igor; Sipos, György; Ruman, Albert; Putniković, Suzana; Emunds, Kathrin; Perić, Zoran; Hambach, Ulrich; Lehmkuhl, Frank

    2018-04-01

    This study utilizes four different methodological approaches to examine the prevailing surface winds and their associated aeolian processes in Northern Serbia, focusing on the southeastern part of the Carpathian Basin. We utilized wind and atmospheric pressure data from 1939-2014 and 1960-2010 for the climatological analyses. Geomorphological data and numerical simulations were used to estimate prevailing paleowind systems. Northern Serbia is currently dominated by surface winds coming from the fourth (270°-360°) and second (90°-180°) quadrants, with frequencies of ca. 116 and 105 days/year, respectively. Comparable frequencies within Banatska Peščara are 115 and 129 days/year, respectively. Crestal orientations of the vast majority of the ≈1300 parabolic dunes here suggest that they have formed from winds derived from the second quadrant, indicating formation during the early Holocene. The remaining dunes, of the transverse type, have orientations aligned to the third quadrant. Grain size analysis of loess deposits near Banatska Peščara points to deposition driven by southeasterly winds, probably during the period between the Last Glacial Maximum (LGM) and the early Holocene. Modern wind measurements and geomorphological data showed that the prevailing winds in the recent and past periods were from the same quadrant, in and around Banatska Peščara. These results were confirmed with an explicit numerical simulation that modelled prevailing winds from the second quadrant during the LGM. Thus, the various geomorphologic and climatic data analyzed in this study show that the general air circulation patterns in the recent period are not dissimilar to those operative during the LGM.

  7. Venous beading in two or more quadrants might not be a sensitive grading criterion for severe nonproliferative diabetic retinopathy.

    PubMed

    Chen, Ling; Zhang, Xiongze; Wen, Feng

    2018-06-01

    To determine whether venous beading (VB) in two or more quadrants is an appropriate grading criterion for severe nonproliferative diabetic retinopathy (NPDR). A hospital-based, retrospective, cross-sectional study. A total of 806 patients admitted with diabetic retinopathy (DR) from January 2014 to April 2017 were included in this study. DR severity was graded by the international grading criterion. The status of VB, intraretinal microvascular abnormalities (IRMA), capillary nonperfusion, arteriovenous nicking, and diabetic macular edema was evaluated based on fundus fluorescein angiography. The prevalence of VB in eyes with proliferative diabetic retinopathy (PDR), severe NPDR, and moderate NPDR was 41.3% (327/791), 5.9% (31/526), and 0% (0/295), respectively (p < 0.001). Moreover, the proportion of VB in two or more quadrants was even lower (27.1% for PDR and 2.1% for severe NPDR, p < 0.001), and among the total of 225 eyes with VB in two or more quadrants, 214 eyes (95.1%) were graded as PDR. Furthermore, VB formation was significantly correlated with capillary nonperfusion, duration of diabetes (both p < 0.001), and smoking (p < 0.05). After adjusting for age, sex, and other possible factors, VB (OR = 7.479, p < 0.001) and IRMA (OR = 2.433, p < 0.001) were determined as independent risk factors for developing PDR. Our study suggested that VB in two or more quadrants might not be a sensitive grading criterion for severe NPDR among a Chinese population with type 2 diabetes. Nevertheless, VB has a great specificity to define an advanced form of DR.

  8. [Choledocholithiasis and pregnancy. Hybrid laparo-endoscopic treatment in one step].

    PubMed

    Valadez-Caballero, David; González-Santamaría, Roberto; Soto-Mendoza, Héctor; Alberto Blanco-Figueroa, Jorge; Flores-Pantoja, Juan Manuel

    2014-01-01

    Complications associated with choledocholithiasis are uncommon during pregnancy. However, when it occurs, the morbidity and mortality related for the product and the mother increases, so a proper treatment is imperative in these patients. A 25-year-old pregnant woman on her second trimester. The current condition was started four days prior to the hospital admission with abdominal pain in the right upper quadrant with nausea and vomit.Twenty-four hours later jaundice and dark urine is observed. Physical examination shows scleral jaundice, right upper quadrant abdominal pain without peritoneal irritation. Uterus at umbilicus level without uterine activity. Uterus at umbilicus level without uterine activity. Laboratory tests showed elevated bilirubin and transaminases without leukocytosis; ultrasound reported live intrauterine unique product, with a heart rate of 128 beats per minute, gallbladder with multiple images inside that cast acoustic shadowing, and a 10 mm common bile duct dilated bile duct with dilatation of intrahepatic bile ducts. It was perform laparoscopic cholecystectomy with intraoperative cholangiography and placement of a transcystic jaguar guide for selective cannulation of the common bile duct. Intraoperative endoscopic retrograde cholangiopancreatography was performed with endoscopic stone extraction. The outcome was satisfactory with a hospital discharge at 48 hours. Current evidence has shown that the combined use of laparoscopy and therapeutic endoscopic cholangiography in one step is effective for the treatment of choledocholithiasis, decreasing the risk of complications associated with cannulation of the bile duct.

  9. The ALMA correlator

    NASA Astrophysics Data System (ADS)

    Escoffier, R. P.; Comoretto, G.; Webber, J. C.; Baudry, A.; Broadwell, C. M.; Greenberg, J. H.; Treacy, R. R.; Cais, P.; Quertier, B.; Camino, P.; Bos, A.; Gunst, A. W.

    2007-02-01

    Aims: The Atacama Large Millimeter Array (ALMA) is an international astronomy facility to be used for detecting and imaging all types of astronomical sources at millimeter and submillimeter wavelengths at a 5000-m elevation site in the Atacama Desert of Chile. Our main aims are: describe the correlator sub-system which is that part of the ALMA system that combines the signal from up to 64 remote individual radio antennas and forms them into a single instrument; emphasize the high spectral resolution and the configuration flexibility available with the ALMA correlator. Methods: The main digital signal processing features and a block diagram of the correlator being constructed for the ALMA radio astronomy observatory are presented. Tables of observing modes and spectral resolutions offered by the correlator system are given together with some examples of multi-resolution spectral modes. Results: The correlator is delivered by quadrants and the first quadrant is being tested while most of the other printed circuit cards required by the system have been produced. In its final version the ALMA correlator will process the outputs of up to 64 antennas using an instantaneous bandwidth of 8 GHz in each of two polarizations per antenna. In the frequency division mode, unrivalled spectral flexibility together with very high resolution (3.8 kHz) and up to 8192 spectral points are achieved. In the time division mode high time resolution is available with minimum data dump rates of 16 ms for all cross-products.

  10. CHOROIDAL THICKNESS IN HEALTHY CHINESE CHILDREN AGED 6 to 12: The Shanghai Children Eye Study.

    PubMed

    He, Xiangui; Jin, Peiyao; Zou, Haidong; Li, Qiangqiang; Jin, Jiali; Lu, Lina; Zhao, Huijuan; He, Jiangnan; Xu, Xun; Wang, Mingjin; Zhu, Jianfeng

    2017-02-01

    To explore the characteristics of choroidal thickness (ChT) in Chinese children. A total of 144 healthy children, aged 6 years to 12 years old, were enrolled in the study. The ChT of subfovea and peripheral locations 0.5, 1.5, and 2.5 mm away from the fovea were evaluated by enhanced depth imaging optical coherence tomography. The association between subfoveal ChT and systemic, as well as ocular factors, including age, sex, height, weight, body mass index, axial length, refractive error, intraocular pressure, preterm history, and the refractive status of parents were studied. The mean subfoveal ChT was 302 ± 63 μm. In the nasal, superior, and inferior areas, the ChT of locations closer to the fovea was thicker than those farther away from the fovea (all P < 0.05); however, ChT was not significantly different among different locations in the temporal area (P = 0.16). The ChT of the nasal quadrant was significantly thinner than that of other areas (P < 0.01). Subfoveal ChT decreased with age, axial length, preterm history, and increased with height. Sex was not statistically associated with subfoveal ChT. In Chinese children, the ChT is thinnest in the nasal quadrant and thicker in central regions than in peripheral areas. The subfoveal ChT independently decreases with age, axial length, preterm history, and increases with height.

  11. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hirvonen, Liisa M.; Le Marois, Alix; Suhling, Klaus, E-mail: klaus.suhling@kcl.ac.uk

    We perform wide-field time-correlated single photon counting-based fluorescence lifetime imaging (FLIM) with a crossed delay line anode image intensifier, where the pulse propagation time yields the photon position. This microchannel plate-based detector was read out with conventional fast timing electronics and mounted on a fluorescence microscope with total internal reflection (TIR) illumination. The picosecond time resolution of this detection system combines low illumination intensity of microwatts with wide-field data collection. This is ideal for fluorescence lifetime imaging of cell membranes using TIR. We show that fluorescence lifetime images of living HeLa cells stained with membrane dye di-4-ANEPPDHQ exhibit a reducedmore » lifetime near the coverslip in TIR compared to epifluorescence FLIM.« less

  12. Minor psychiatric disorders among nurses university faculties.

    PubMed

    Tavares, Juliana Petri; Beck, Carmem Lúcia Colomé; Magnago, Tânia Solange Bosi de Souza; Zanini, Roselaine Ruviaro; Lautert, Liana

    2012-01-01

    This cross-sectional study addresses 130 nursing faculty members in federal universities from Rio Grande do Sul, Brazil. It investigated the psychological demands and decision latitude (the Demand-Control Model by Karasek) and their association with Minor Psychological Disorders (MPDs). The Brazilian versions of the Self-Report-Questionnaire-20 and the Job Stress Scale were used. MPDs were prevalent in 20% of the studied individuals. After adjusting for potential confounders, the chances of participants presenting mental disorders were higher in the quadrant 'active strain jobs' (OR=14.23, 95% CI 1.55 to 130.73), followed by the 'high strain jobs' quadrant (OR=10.05, 95% CI 1.23 to 82.44), compared to nursing professors classified in the 'low strain jobs' quadrant. We conclude that high psychological demands and low control over work can cause disorders in nursing professors, among them, MPDs.

  13. First saccadic eye movement reveals persistent attentional guidance by implicit learning

    PubMed Central

    Jiang, Yuhong V.; Won, Bo-Yeong; Swallow, Khena M.

    2014-01-01

    Implicit learning about where a visual search target is likely to appear often speeds up search. However, whether implicit learning guides spatial attention or affects post-search decisional processes remains controversial. Using eye tracking, this study provides compelling evidence that implicit learning guides attention. In a training phase, participants often found the target in a high-frequency, “rich” quadrant of the display. When subsequently tested in a phase during which the target was randomly located, participants were twice as likely to direct the first saccadic eye movement to the previously rich quadrant than to any of the sparse quadrants. The attentional bias persisted for nearly 200 trials after training and was unabated by explicit instructions to distribute attention evenly. We propose that implicit learning guides spatial attention but in a qualitatively different manner than goal-driven attention. PMID:24512610

  14. Jupiter Polar Winds Movie Blowup

    NASA Technical Reports Server (NTRS)

    2001-01-01

    Persistent polar storms and zonal winds on Jupiter can be seen in this magnified quadrant from a movie projecting images from NASA's Cassini spacecraft as if the viewer were looking down at Jupiter's north pole and the planet were flattened.

    The sequence covers 70 days, from October 1 to December 9, 2000. Cassini's narrow-angle camera captured the images of Jupiter's atmosphere in the near-infrared region of the spectrum.

    Like the accompanying full-circle movie of polar winds, this zoomed-inversion shows that the polar region has coherent flows, despite its chaotic, mottled appearance. There are thousands of spots, each an active storm similar in size to the largest storms on Earth. The spots occasionally change latitude or merge with each other, but usually they last for the entire 70 days. Until now, the lifetime of those storms was unknown.

    The mystery of Jupiter's weather is why the storms last so long. Storms on Earth last for a week before they break up and are replaced by other storms. This movie heightens the mystery because it shows long-lived storms at the highest latitudes, where the weather patterns are more disorganized than at low latitudes.

    Cassini collected images of Jupiter for months before and after it passed the planet on December 30, 2000. Six images or more of the planet in each of several spectral filters were taken at evenly spaced intervals over the course of Jupiter's 10-hour rotation period. The entire sequence was repeated generally every other Jupiter rotation, yielding views of every sector of the planet at least once every 20 hours.

    The images used for the movie shown here were taken every 20 hours through a filter centered at a wavelength of 756 nanometers, where there are almost no absorptions in the planet's atmosphere. Images from each rotation were assembled first into a cylindrical map. The 84 resulting cylindrical maps, spanning 70 Earth days or 168 Jupiter rotations, were transformed to polar stereographic projections, making a map centered on the north pole. This clip shows detail by zooming in on one quadrant of the full-circle polar projection. Jupiter's alternating eastward and westward jet streams flow in concentric rings around the pole.

    For more information, see the Cassini Project home page, http://www.jpl.nasa.gov/cassini/ and the Cassini Imaging Team home page, http://ciclops.lpl.arizona.edu/ciclops/ .

    Cassini is a cooperative project of NASA, the European Space Agency and the Italian Space Agency. The Jet Propulsion Laboratory, a division of the California Institute of Technology in Pasadena, manages the Cassini mission for NASA's Office of Space Science, Washington, D.C.

  15. Risk Score for Predicting Treatment-Requiring Retinopathy of Prematurity (ROP) in the Telemedicine Approaches to Evaluating Acute-Phase ROP Study.

    PubMed

    Ying, Gui-Shuang; VanderVeen, Deborah; Daniel, Ebenezer; Quinn, Graham E; Baumritter, Agnieshka

    2016-10-01

    To develop a risk score for predicting treatment-requiring retinopathy of prematurity (TR-ROP) in the Telemedicine Approaches to Evaluating Acute-Phase Retinopathy of Prematurity (e-ROP) study. Second analyses of an observational cohort study. Infants with birth weight (BW) <1251 g who had ≥1 imaging session by 34 weeks of postmenstrual age (PMA) and ≥1 subsequent retinopathy of prematurity (ROP) examination for determining TR-ROP by study-certified ophthalmologists. Nonphysician trained readers evaluated wide-field retinal image sets for characteristics of ROP, pre-plus/plus disease, and retinal hemorrhage. Risk score points for predicting TR-ROP were derived from the regression coefficients of significant predictors in a multivariate logistic regression model. TR-ROP. Eighty-five of 771 infants (11.0%) developed TR-ROP. In a multivariate model, significant predictors for TR-ROP were gestational age (GA) (odds ratio [OR], 5.7; 95% confidence interval [CI], 1.7-18.9 for ≤25 vs. ≥28 weeks), need for respiratory support (OR, 7.0; 95% CI, 1.3-37.1 for high-frequency oscillatory ventilation vs. no respiratory support), slow weight gain (OR, 2.4; 95% CI, 1.2-4.6 for weight gain ≤12 g/day vs. >15 g/day), and image findings at the first image session including number of quadrants with pre-plus (OR, 3.8; 95% CI, 1.5-9.7 for 4 pre-plus quadrants vs. no pre-plus), stage and zone of ROP (OR, 4.7; 95% CI, 2.1-11.8 for stage 1-2 zone I, OR, 5.9; 95% CI, 2.1-16.6 for stage 3 zone I vs. no ROP), and presence of blot hemorrhage (OR, 3.1; 95% CI, 1.4-6.7). Image findings predicted TR-ROP better than GA (area under receiver operating characteristic curve [AUC] = 0.82 vs. 0.75, P = 0.03). The risk of TR-ROP steadily increased with higher risk score and predicted TR-ROP well (AUC = 0.88; 95% CI, 0.85-0.92). Risk score ≥3 points for predicting TR-ROP had a sensitivity of 98.8%, specificity of 40.1%, and positive and negative predictive values of 17.0% and 99.6%, respectively. Image characteristics at 34 PMA weeks or earlier independently predict TR-ROP. If externally validated in other infants, risk score, calculated from image findings, GA, weight gain, and respiratory support, enables early identification of infants in need of increased surveillance for TR-ROP. Copyright © 2016 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

  16. Radiographic landmarks for locating the femoral origin of the superficial medial collateral ligament.

    PubMed

    Hartshorn, Timothy; Otarodifard, Karimdad; White, Eric A; Hatch, George F Rick

    2013-11-01

    Little has been written about the use of radiographic landmarks for locating the origin of the superficial medial collateral ligament (sMCL). A standardized radiographic landmark for the sMCL origin using intraoperative fluoroscopic imaging may be of value in aiding the surgeon in accurate femoral tunnel placement in the setting of extensive soft tissue disruption and bony attrition. To determine a reproducible radiographic landmark that will assist in correct femoral tunnel placement in sMCL repair and reconstruction. Descriptive laboratory study. Ten fresh-frozen unmatched human cadaveric knees were dissected, and the origin of the sMCL was exposed. A 2-mm metallic marker was then placed at the center of the femoral origin of the sMCL. True lateral fluoroscopically assisted digital radiographs were obtained of the knee with the posterior and distal femoral condyles overlapping in a standardized fashion. With the use of computer software, reference lines were drawn on the images, creating 4 quadrants. Two independent examiners performed quantitative measurements of the sMCL origin in relation to this axis and to the Blumensaat line. Mean measurements showed the sMCL origin to be closely related to the intersection point of the Blumensaat line and a line drawn distally from the posterior femoral cortex on a true lateral radiograph. The sMCL origin was found at a mean point 1.6 ± 4.3 mm posterior and 4.9 ± 2.1 mm proximal to the intersection of a line paralleling the posterior femoral cortex and a line drawn perpendicular to the posterior femoral cortical line, where it intersects the Blumensaat line. In 5 of 10 specimens, the center of the sMCL origin fell precisely on the Blumensaat line. The remaining specimens had sMCL origins anterior to the Blumensaat line. The femoral origin of the sMCL was found in the proximal and posterior quadrants in 8 of 10 specimens. With a relatively small amount of deviation, the sMCL origin can be consistently identified on a true lateral radiograph of the knee using reproducible reference lines on fluoroscopic imaging. Accurate identification of the femoral origin of the sMCL can be accomplished by intraoperative fluoroscopic imaging. This information may be of significant benefit in repairing acute injuries and in reconstructive procedures complicated by bony attrition and soft tissue loss.

  17. Engineering and performance (NEMA and animal) of a lower-cost higher-resolution animal PET/CT scanner using photomultiplier-quadrant-sharing detectors.

    PubMed

    Wong, Wai-Hoi; Li, Hongdi; Baghaei, Hossain; Zhang, Yuxuan; Ramirez, Rocio A; Liu, Shitao; Wang, Chao; An, Shaohui

    2012-11-01

    The dedicated murine PET (MuPET) scanner is a high-resolution, high-sensitivity, and low-cost preclinical PET camera designed and manufactured at our laboratory. In this article, we report its performance according to the NU 4-2008 standards of the National Electrical Manufacturers Association (NEMA). We also report the results of additional phantom and mouse studies. The MuPET scanner, which is integrated with a CT camera, is based on the photomultiplier-quadrant-sharing concept and comprises 180 blocks of 13 × 13 lutetium yttrium oxyorthosilicate crystals (1.24 × 1.4 × 9.5 mm(3)) and 210 low-cost 19-mm photomultipliers. The camera has 78 detector rings, with an 11.6-cm axial field of view and a ring diameter of 16.6 cm. We measured the energy resolution, scatter fraction, sensitivity, spatial resolution, and counting rate performance of the scanner. In addition, we scanned the NEMA image-quality phantom, Micro Deluxe and Ultra-Micro Hot Spot phantoms, and 2 healthy mice. The system average energy resolution was 14% at 511 keV. The average spatial resolution at the center of the field of view was about 1.2 mm, improving to 0.8 mm and remaining below 1.2 mm in the central 6-cm field of view when a resolution-recovery method was used. The absolute sensitivity of the camera was 6.38% for an energy window of 350-650 keV and a coincidence timing window of 3.4 ns. The system scatter fraction was 11.9% for the NEMA mouselike phantom and 28% for the ratlike phantom. The maximum noise-equivalent counting rate was 1,100 at 57 MBq for the mouselike phantom and 352 kcps at 65 MBq for the ratlike phantom. The 1-mm fillable rod was clearly observable using the NEMA image-quality phantom. The images of the Ultra-Micro Hot Spot phantom also showed the 1-mm hot rods. In the mouse studies, both the left and right ventricle walls were clearly observable, as were the Harderian glands. The MuPET camera has excellent resolution, sensitivity, counting rate, and imaging performance. The data show it is a powerful scanner for preclinical animal study and pharmaceutical development.

  18. Scanning probes for lithography: Manipulation and devices

    NASA Astrophysics Data System (ADS)

    Rolandi, Marco

    2005-11-01

    Scanning probes are relatively low cost equipment that can push the limit of lithography in the nanometer range, with the advantages of high resolution, accuracy in the positioning of the overlayers and no proximity aberrations. We have developed three novel scanning probe lithography (SPL) resists based on thin films of Titanium, Molybdenum and Tungsten and we have manipulated single walled carbon nanotubes using the sharp tip of an atomic force microscope (AFM) for the fabrication of nanostructures. A dendrimer-passivated Ti film was imaged in the positive and the negative tone using SPL. This is the first example of SPL imaging in both tones using a unique resist. Positive tone patterning was obtained by locally scribing the dendrimer molecules and subsequent acid etch of the deprotected Ti film. Local anodic oxidation transforms Ti into TiO2 and deposits a thin layer of amorphous carbon on the patterned areas. This is very resistive to base etch and affords negative tone imaging of the Ti surface. Molybdenum and Tungsten were patterned using local anodic oxidation. This scheme is particularly flexible thanks to the solubility in water of the fully oxidized states of the two metals. We will present the facile fabrication of several nanostructures such as of trenches, dots wires and nanoelectrodes and show the potential of this scheme for competing with conventional lithographic techniques based on radiation. Quasi one dimensional electrodes for molecular electronics applications were also fabricated by creating nanogaps in single walled carbon nanotubes. The tubes, connected to microscopic contacts, were controllably cut via local anodic oxidation using the tip of the AFM. This technique leads to nanoscopic carboxyl terminated wires to which organic molecules can be linked using covalent chemistry. This geometry is particularly useful for the high gate efficiency without the need of a thin gate dielectric and the stability of the junction. Room temperature and low temperature measurements were performed and show single electron transistor behavior for the molecular junction.

  19. Transforming Norwegian Special Operation Forces

    DTIC Science & Technology

    2006-06-01

    Justice and Police. This pertains to the Coast Guard maintaining 146 Ole M. Rapp, "Får Europas Beste Marine [the Best Navy in Europe]," Aftenposten...service affiliation. Both units collectively represent capabilities within quadrant 1 and 2 of Figure 15. This is the flexibility NORSOF is assumed...reference to SOF’s domain. However, if indirect action capabilities are required or desired within both quadrants 3 and 4, domain matters. The

  20. Suppression of the Near Wall Burst Process of a Fully Developed Turbulent Pipe Flow

    DTIC Science & Technology

    1993-05-01

    tunmel turbulent boundary layer a) velocity fluctuation skewness levels and b) velocity fluctuation kurtosis levels ...by the undisturbed total uv level and u*. a) quadrants I and 2 and b) quadrants 3 and 4 ...................... 105 5.20 Spanwise development of the uw...and radial velocity skewness levels . Normalization with ref. u". .............................. 111 xi 5.23 Spanwise development of profi!s of the

  1. Quadrantal multi-scale distribution entropy analysis of heartbeat interval series based on a modified Poincaré plot

    NASA Astrophysics Data System (ADS)

    Huo, Chengyu; Huang, Xiaolin; Zhuang, Jianjun; Hou, Fengzhen; Ni, Huangjing; Ning, Xinbao

    2013-09-01

    The Poincaré plot is one of the most important approaches in human cardiac rhythm analysis. However, further investigations are still needed to concentrate on techniques that can characterize the dispersion of the points displayed by a Poincaré plot. Based on a modified Poincaré plot, we provide a novel measurement named distribution entropy (DE) and propose a quadrantal multi-scale distribution entropy analysis (QMDE) for the quantitative descriptions of the scatter distribution patterns in various regions and temporal scales. We apply this method to the heartbeat interval series derived from healthy subjects and congestive heart failure (CHF) sufferers, respectively, and find that the discriminations between them are most significant in the first quadrant, which implies significant impacts on vagal regulation brought about by CHF. We also investigate the day-night differences of young healthy people, and it is shown that the results present a clearly circadian rhythm, especially in the first quadrant. In addition, the multi-scale analysis indicates that the results of healthy subjects and CHF sufferers fluctuate in different trends with variation of the scale factor. The same phenomenon also appears in circadian rhythm investigations of young healthy subjects, which implies that the cardiac dynamic system is affected differently in various temporal scales by physiological or pathological factors.

  2. Changes in serum interleukin-6, C-reactive protein and thrombomodulin levels under periodontal ultrasonic debridement.

    PubMed

    Ushida, Yuka; Koshy, Geena; Kawashima, Yoko; Kiji, Makoto; Umeda, Makoto; Nitta, Hiroshi; Nagasawa, Toshiyuki; Ishikawa, Isao; Izumi, Yuichi

    2008-11-01

    This study aimed to compare the effect of single-visit full-mouth mechanical debridement (FMD) and quadrant-wise mechanical debridement (QMD) on the levels of serum interleukin (IL)-6, C-reactive protein (CRP) and soluble thrombomodulin. Thirty-six subjects with chronic periodontitis were randomly allocated to three groups: undergoing QMD, single-visit FMD with povidone iodine or with water. Serum IL-6 and soluble thrombomodulin were measured by enzyme-linked immunosorbent assay, and serum CRP was measured by the latex-enhanced nephelometric method. Serum IL-6 level increased significantly immediately after debridement in all the three groups, with this increase being greatest in the full-mouth groups. However, the increase in the full-mouth groups was not significantly higher than that of quadrant-wise group. In the quadrant-wise group, serum IL-6 level decreased significantly 1 month after debridement compared with baseline. Serum-soluble thrombomodulin decreased significantly in the full-mouth groups but not in the quadrant-wise group. Changes in CRP level were not significant at baseline or after debridement in all the three groups. FMD increased serum IL-6 and reduced serum-soluble thrombomodulin to a greater extent than QMD, suggesting that the former technique has stronger transient effects on systemic vascular endothelial functions than the latter.

  3. Age-dependent effects of brain stimulation on network centrality.

    PubMed

    Antonenko, Daria; Nierhaus, Till; Meinzer, Marcus; Prehn, Kristin; Thielscher, Axel; Ittermann, Bernd; Flöel, Agnes

    2018-04-18

    Functional magnetic resonance imaging (fMRI) studies have suggested that advanced age may mediate the effects of transcranial direct current stimulation (tDCS) on brain function. However, studies directly comparing neural tDCS effects between young and older adults are scarce and limited to task-related imaging paradigms. Resting-state (rs-) fMRI, that is independent of age-related differences in performance, is well suited to investigate age-associated differential neural tDCS effects. Three "online" tDCS conditions (anodal, cathodal, sham) were compared in a cross-over, within-subject design, in 30 young and 30 older adults. Active stimulation targeted the left sensorimotor network (active electrode over left sensorimotor cortex with right supraorbital reference electrode). A graph-based rs-fMRI data analysis approach (eigenvector centrality mapping) and complementary seed-based analyses characterized neural tDCS effects. An interaction between anodal tDCS and age group was observed. Specifically, centrality in bilateral paracentral and posterior regions (precuneus, superior parietal cortex) was increased in young, but decreased in older adults. Seed-based analyses revealed that these opposing patterns of tDCS-induced centrality modulation originated from differential effects of tDCS on functional coupling of the stimulated left paracentral lobule. Cathodal tDCS did not show significant effects. Our study provides first evidence for differential tDCS effects on neural network organization in young and older adults. Anodal stimulation mainly affected coupling of sensorimotor with ventromedial prefrontal areas in young and decoupling with posteromedial areas in older adults. Copyright © 2018 Elsevier Inc. All rights reserved.

  4. Cross delay line sensor characterization

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Owens, Israel J; Remelius, Dennis K; Tiee, Joe J

    There exists a wealth of information in the scientific literature on the physical properties and device characterization procedures for complementary metal oxide semiconductor (CMOS), charge coupled device (CCD) and avalanche photodiode (APD) format detectors. Numerous papers and books have also treated photocathode operation in the context of photomultiplier tube (PMT) operation for either non imaging applications or limited night vision capability. However, much less information has been reported in the literature about the characterization procedures and properties of photocathode detectors with novel cross delay line (XDL) anode structures. These allow one to detect single photons and create images by recordingmore » space and time coordinate (X, Y & T) information. In this paper, we report on the physical characteristics and performance of a cross delay line anode sensor with an enhanced near infrared wavelength response photocathode and high dynamic range micro channel plate (MCP) gain (> 10{sup 6}) multiplier stage. Measurement procedures and results including the device dark event rate (DER), pulse height distribution, quantum and electronic device efficiency (QE & DQE) and spatial resolution per effective pixel region in a 25 mm sensor array are presented. The overall knowledge and information obtained from XDL sensor characterization allow us to optimize device performance and assess capability. These device performance properties and capabilities make XDL detectors ideal for remote sensing field applications that require single photon detection, imaging, sub nano-second timing response, high spatial resolution (10's of microns) and large effective image format.« less

  5. Airborne 3D Imaging Lidar for Contiguous Decimeter Resolution Terrain Mapping and Shallow Water Bathymetry

    NASA Astrophysics Data System (ADS)

    Degnan, J. J.; Wells, D. N.; Huet, H.; Chauvet, N.; Lawrence, D. W.; Mitchell, S. E.; Eklund, W. D.

    2005-12-01

    A 3D imaging lidar system, developed for the University of Florida at Gainesville and operating at the water transmissive wavelength of 532 nm, is designed to contiguously map underlying terrain and/or perform shallow water bathymetry on a single overflight from an altitude of 600 m with a swath width of 225 m and a horizontal spatial resolution of 20 cm. Each 600 psec pulse from a frequency-doubled, low power (~3 microjoules @ 8 kHz = 24 mW), passively Q-switched Nd:YAG microchip laser is passed through a holographic element which projects a 10x10 array of spots onto a 2m x 2m target area. The individual ground spots are then imaged onto individual anodes within a 10x10 segmented anode photomultiplier. The latter is followed by a 100 channel multistop ranging receiver with a range resolution of about 4 cm. The multistop feature permits single photon detection in daylight with wide range gates as well as multiple single photon returns per pixel per laser fire from volumetric scatterers such as tree canopies or turbid water columns. The individual single pulse 3D images are contiguously mosaiced together through the combined action of the platform velocity and a counter-rotating dual wedge optical scanner whose rotations are synchronized to the laser pulse train. The paper provides an overview of the lidar opto-mechanical design, the synchronized dual wedge scanner and servo controller, and the experimental results obtained to date.

  6. Fabrication and characterization of anode-supported micro-tubular solide oxide fuel cell by phase inversion method

    NASA Astrophysics Data System (ADS)

    Ren, Cong

    Nowadays, the micro-tubular solid oxide fuel cells (MT-SOFCs), especially the anode supported MT-SOFCs have been extensively developed to be applied for SOFC stacks designation, which can be potentially used for portable power sources and vehicle power supply. To prepare MT-SOFCs with high electrochemical performance, one of the main strategies is to optimize the microstructure of the anode support. Recently, a novel phase inversion method has been applied to prepare the anode support with a unique asymmetrical microstructure, which can improve the electrochemical performance of the MT-SOFCs. Since several process parameters of the phase inversion method can influence the pore formation mechanism and final microstructure, it is essential and necessary to systematically investigate the relationship between phase inversion process parameters and final microstructure of the anode supports. The objective of this study is aiming at correlating the process parameters and microstructure and further preparing MT-SOFCs with enhanced electrochemical performance. Non-solvent, which is used to trigger the phase separation process, can significantly influence the microstructure of the anode support fabricated by phase inversion method. To investigate the mechanism of non-solvent affecting the microstructure, water and ethanol/water mixture were selected for the NiO-YSZ anode supports fabrication. The presence of ethanol in non-solvent can inhibit the growth of the finger-like pores in the tubes. With the increasing of the ethanol concentration in the non-solvent, a relatively dense layer can be observed both in the outside and inside of the tubes. The mechanism of pores growth and morphology obtained by using non-solvent with high concentration ethanol was explained based on the inter-diffusivity between solvent and non-solvent. Solvent and non-solvent pair with larger Dm value is benefit for the growth of finger-like pores. Three cells with different anode geometries was prepared, La0.85Sr0.15MnO 3 (LSM) was selected as the cathode. Cells were tested at 800°C using humidified H2 as fuel. Cell with anode prepared by using pure water as non-solvent shows a maximum power density up to 437mW/cm 2. By comparing the anode geometry and electrochemical performance, it indicated that microstructure with longer finger-like pores and thinner macrovoid free layer close to the inner side of the tube is benefit to cell performance. Another factor that can affect the microstructure of anode support is the ratio of solvent and polymer binder. In this research, anode-supported MT-SOFCs have been fabricated by phase inversion method. The effect of the viscosity of the casting slurry on the microstructure of YSZ-NiO anode support has been investigated. The microstructure of the YSZ-NiO support can be effectively controlled by varying the slurry composition with different solvent and polymer binder content. Gas permeation and mechanical strength of the YSZ-NiO support have been measured and four YSZ-NiO anode supports have been chosen for subsequent cell fabrication. The effective conductivity of the different anode supports has been measured at room temperature after reduced. Anode-supported single cells with YSZ electrolyte and LSM/YSZ cathode are fabricated and tested. Maximum cell power densities of 606 mWcm-2, 449 mWcm -2, 339 mWcm-2 and 253 mWcm-2 have been obtained respectively at 750 °C with humidified hydrogen as fuel and ambient air as oxidant. The correlation between the cell electrochemical performance and anode microstructures has been discussed. Adjusting the slurry composition by introducing additive is also an effective approach to tailor the microstructure of the anode support. Poly(ethylene glycol) (PEG), which is a common applied polymer additive, was selected to fabricate the YSZ-NiO anode supports. The effect of molecular weight and amount of PEG additive on the thermodynamics of the casting solutions was characterized by measuring the coagulation value. Viscosity of the casting slurries was also measured and the influence of PEG additive on viscosity was studied and discussed. The presence of PEG in the casting slurry can greatly influence the final anode support microstructure. Based on the microstructure result and the measured gas permeation value, two anode supports were selected for cell fabrication. For cell with the anode support fabricated using slurry with PEG additive, a maximum cell power density of 704 mWcm-2 is obtained at 750 oC with humidified hydrogen as fuel and ambient air as oxidant; cell fabricated without any PEG additive shows the peak cell power density of 331 mWcm-2. The relationship between anode microstructure and cell performance was discussed. Anode-supported micro-tubular solid oxide fuel cells (MT-SOFCs) based on BaZr0.1Ce0.7Y0.1Yb0.1O 3-delta (BZCYYb) proton-conducting electrolyte have been prepared using a phase inversion method. Three sulfur-free polymer binder candidates ethyl cellulose (EC), polyvinylidene fluoride (PVDF), polyetherimide (PEI) and sulfur-containing polythersulfone (PESf) were used as polymer binders to fabricate NiO-BZCYYb anode. The overall influence of polymer binder on the anode supports was evaluated. Sulfide impurity generated from PESf was revealed by XRD and X-ray photoelectron spectroscopy (XPS). The difference in the anode microstructure for samples fabricated by different polymer binders was examined by scanning electron microscope (SEM) and analyzed by measuring the gas permeation data of the reduced samples. Single cells based on different anode supports were characterized in anode-supported MT-SOFCs with the cell configuration of Ni-BZCYYb anode, BZCYYb electrolyte and La0.6Sr 0.4Co0.2Fe0.8O3-delta (LSCF)-BZCYYb cathode at 650 °C using hydrogen as fuel and ambient air as oxidant. MT-SOFCs of the anode fabricated using PEI show maximum power density of 0.45 Wcm -2 compared with 0.35 Wcm-2 for cells fabricated with PESf. The difference in cell performance was attributed to the phase purity of the anode fabricated by different polymer binders. Sulfur-free polymer binder PEI exhibits advantages over the commonly applied PESf and other sulfur-free polymer binder candidates. To eliminate the skin layer formed close to the inner side of the tubular sample when using the phase inversion method. Polyethersulfone (PESf)-polyethylenimine (PEI) blend was employed as the polymer binder to fabricate the micro-tubular solid oxide fuel cells (MT-SOFCs). The potential impurity introduced in the anode support by the polymer binder was examined by XPS and the resulting novel microstructure was analyzed based on the backscattered electron (BSE) images. Cells fabricated with blend polymer binder showed significantly enhanced power output compared with those cells only fabricated with PEI or PESf. The improved cell performance demonstrated that using blend polymer as binder is a promising and versatile approach for MT-SOFC fabrication via phase inversion method. Finally, to investigate the effect of the anode microstructure on the total cell performance, two types of anode support with different microstructure were prepared via the phase inversion method at different temperature. Cells fabricated based on these two anode supports were tested at 750 °C with hydrogen or hydrogen mixture with fuel gas. The measured current density-voltage (I-V) curves were fitted by a polarization model, and several parameters were archived through the modeling process. The influence of the anode support on the total cell performance was discussed based on the calculated result.

  7. Ocular radioimmunoscintigraphy: sensitivity and practical considerations.

    PubMed

    Bomanji, J; Nimmon, C C; Hungerford, J L; Solanki, K; Granowska, M; Britton, K E

    1988-06-01

    Ocular radioimmunoscintigraphy was performed in 20 patients using 99mTc-labeled monoclonal antibody 225.28S, F(ab')2 fragments. Radioimmunoscintigraphy was positive in 13 patients and the diagnosis of ocular melanoma was confirmed by enucleation of the eye or clinical follow-up. Scintigraphy was positive in one patient with lymph node metastasis from an ocular melanoma. In six patients immunoscintigraphy was negative. Using this technique a sensitivity of 92.8% was achieved for detecting ocular melanomas. Single photon emission tomography helped to separate the lesions situated in the nasal quadrant of the eye from the adjacent nasopharyngeal activity. With appropriate imaging techniques small tumors of the order of 3 x 5 x 3 mm could be detected clearly.

  8. Nuclear Science Symposium, 25th, and Symposium on Nuclear Power Systems, 10th, Washington, D.C., October 18-20, 1978, Proceedings

    NASA Technical Reports Server (NTRS)

    1979-01-01

    Detectors of various types are discussed, taking into account drift chambers, calorimetry, multiwire proportional chambers, signal processing, the use of semiconductors, and photo/optical applications. Circuits are considered along with instrumentation for space, nuclear medicine instrumentation, data acquisition and systems, environmental instrumentation, reactor instrumentation, and nuclear power systems. Attention is given to a new approach to high accuracy gaseous detectors, the current status of electron mobility and free-ion yield in high mobility liquids, a digital drift chamber digitizer system, the stability of oxides in high purity germanium, the quadrant photomultiplier, and the theory of imaging with a very limited number of projections.

  9. Ultra-High Density Single Nanometer-Scale Anodic Alumina Nanofibers Fabricated by Pyrophosphoric Acid Anodizing

    NASA Astrophysics Data System (ADS)

    Kikuchi, Tatsuya; Nishinaga, Osamu; Nakajima, Daiki; Kawashima, Jun; Natsui, Shungo; Sakaguchi, Norihito; Suzuki, Ryosuke O.

    2014-12-01

    Anodic oxide fabricated by anodizing has been widely used for nanostructural engineering, but the nanomorphology is limited to only two oxides: anodic barrier and porous oxides. Therefore, the discovery of an additional anodic oxide with a unique nanofeature would expand the applicability of anodizing. Here we demonstrate the fabrication of a third-generation anodic oxide, specifically, anodic alumina nanofibers, by anodizing in a new electrolyte, pyrophosphoric acid. Ultra-high density single nanometer-scale anodic alumina nanofibers (1010 nanofibers/cm2) consisting of an amorphous, pure aluminum oxide were successfully fabricated via pyrophosphoric acid anodizing. The nanomorphologies of the anodic nanofibers can be controlled by the electrochemical conditions. Anodic tungsten oxide nanofibers can also be fabricated by pyrophosphoric acid anodizing. The aluminum surface covered by the anodic alumina nanofibers exhibited ultra-fast superhydrophilic behavior, with a contact angle of less than 1°, within 1 second. Such ultra-narrow nanofibers can be used for various nanoapplications including catalysts, wettability control, and electronic devices.

  10. Ultra-High Density Single Nanometer-Scale Anodic Alumina Nanofibers Fabricated by Pyrophosphoric Acid Anodizing

    PubMed Central

    Kikuchi, Tatsuya; Nishinaga, Osamu; Nakajima, Daiki; Kawashima, Jun; Natsui, Shungo; Sakaguchi, Norihito; Suzuki, Ryosuke O.

    2014-01-01

    Anodic oxide fabricated by anodizing has been widely used for nanostructural engineering, but the nanomorphology is limited to only two oxides: anodic barrier and porous oxides. Therefore, the discovery of an additional anodic oxide with a unique nanofeature would expand the applicability of anodizing. Here we demonstrate the fabrication of a third-generation anodic oxide, specifically, anodic alumina nanofibers, by anodizing in a new electrolyte, pyrophosphoric acid. Ultra-high density single nanometer-scale anodic alumina nanofibers (1010 nanofibers/cm2) consisting of an amorphous, pure aluminum oxide were successfully fabricated via pyrophosphoric acid anodizing. The nanomorphologies of the anodic nanofibers can be controlled by the electrochemical conditions. Anodic tungsten oxide nanofibers can also be fabricated by pyrophosphoric acid anodizing. The aluminum surface covered by the anodic alumina nanofibers exhibited ultra-fast superhydrophilic behavior, with a contact angle of less than 1°, within 1 second. Such ultra-narrow nanofibers can be used for various nanoapplications including catalysts, wettability control, and electronic devices. PMID:25491282

  11. Post-fabrication voltage controlled resonance tuning of nanoscale plasmonic antennas.

    PubMed

    Lumdee, Chatdanai; Toroghi, Seyfollah; Kik, Pieter G

    2012-07-24

    Voltage controlled wavelength tuning of the localized surface plasmon resonance of gold nanoparticles on an aluminum film is demonstrated in single particle microscopy and spectroscopy measurements. Anodization of the Al film after nanoparticle deposition forms an aluminum oxide spacer layer between the gold particles and the Al film, modifying the particle-substrate interaction. Darkfield microscopy reveals ring-shaped scattering images from individual Au nanoparticles, indicative of plasmon resonances with a dipole moment normal to the substrate. Single particle scattering spectra show narrow plasmon resonances that can be tuned from ~580 to ~550 nm as the anodization voltage increases to 12 V. All observed experimental trends could be reproduced in numerical simulations. The presented approach could be used as a general postfabrication resonance optimization step of plasmonic nanoantennas and devices.

  12. Luminescence characteristics of nanoporous anodic alumina annealed at different temperatures

    NASA Astrophysics Data System (ADS)

    Ilin, D. O.; Vokhmintsev, A. S.; Weinstein, I. A.

    2016-09-01

    Anodic aluminum oxide (AAO) membranes with 100 µm thickness were synthesized in oxalic acid solution under constant current density. Grown samples were annealed in 500-1250 °C range for 5 h in air. Average pore diameter was evaluated using quantitative analysis of SEM images and appeared to be within 78-86 nm diapason. It was found there was a broad emission band in the 350-620 nm region of photoluminescence (PL) spectra in amorphous membranes which is attributed to F-type oxygen deficient centers or oxalic ions. It was shown that intensive red emission caused by Cr3+ (696 nm) and Mn4+ (680 nm) impurities dominates in PL of AAO samples with crystalline α- and δ-phases after annealing at 1100-1250 °C temperatures.

  13. Gated strip proportional detector

    DOEpatents

    Morris, C.L.; Idzorek, G.C.; Atencio, L.G.

    1985-02-19

    A gated strip proportional detector includes a gas tight chamber which encloses a solid ground plane, a wire anode plane, a wire gating plane, and a multiconductor cathode plane. The anode plane amplifies the amount of charge deposited in the chamber by a factor of up to 10/sup 6/. The gating plane allows only charge within a narrow strip to reach the cathode. The cathode plane collects the charge allowed to pass through the gating plane on a set of conductors perpendicular to the open-gated region. By scanning the open-gated region across the chamber and reading out the charge collected on the cathode conductors after a suitable integration time for each location of the gate, a two-dimensional image of the intensity of the ionizing radiation incident on the detector can be made.

  14. Gated strip proportional detector

    DOEpatents

    Morris, Christopher L.; Idzorek, George C.; Atencio, Leroy G.

    1987-01-01

    A gated strip proportional detector includes a gas tight chamber which encloses a solid ground plane, a wire anode plane, a wire gating plane, and a multiconductor cathode plane. The anode plane amplifies the amount of charge deposited in the chamber by a factor of up to 10.sup.6. The gating plane allows only charge within a narrow strip to reach the cathode. The cathode plane collects the charge allowed to pass through the gating plane on a set of conductors perpendicular to the open-gated region. By scanning the open-gated region across the chamber and reading out the charge collected on the cathode conductors after a suitable integration time for each location of the gate, a two-dimensional image of the intensity of the ionizing radiation incident on the detector can be made.

  15. Operational characteristics of Wedge and Strip image readout systems

    NASA Technical Reports Server (NTRS)

    Siegmund, O. H. W.; Lampton, M.; Bixler, J.; Bowyer, S.; Malina, R. F.

    1986-01-01

    Application of the Wedge and Strip readout system in microchannel plate detectors for the Extreme Ultraviolet Explorer and FAUST space astronomy programs is discussed. Anode designs with high resolution (greater than 600 x 600 pixels) in imaging and spectroscopy applications have been developed. Extension of these designs to larger formats (100 mm) with higher resolution (3000 x 3000 pixels) are considered. It is shown that the resolution and imaging are highly stable, and that the flat field performance is essentially limited by photon statistics. Very high speed event response has also been achieved with output pulses having durations of less than 10 nanoseconds.

  16. Earth observations taken during STS-98 mission

    NASA Image and Video Library

    2001-02-07

    STS098-714A-020 (7-20 February 2001) ---One of the STS-98 astronauts aboard the Earth-orbiting Space Shuttle Atlantis used a 70mm handheld camera to record this image of Southern California. Snow blanketing the higher elevations in the Los Padres National Forest (center of the image) and that covering the Angeles National Forest (right middle) help to accentuate and separate three major landform regions in southern California. The northern Los Angeles Basin that includes the San Fernando Valley and the Santa Monica Mountains is visible in the lower right quadrant of the image. The western end of the Mojave Desert (upper right) shows the two distinctive mountain boundaries along the southwest and northwest edge of the desert. The San Andreas Fault and the Garlock Fault converge (snow covered in this scene) at the western end of the desert. The intensively irrigated and cultivated southern end of the San Joaquin Valley that includes Bakersfield is visible (upper left) north of the snow-covered, northeast-southwest trending Tehachapi Mountains. The island off of the California coast (bottom left) is Santa Cruz Island.

  17. Multiple splenic abscesses in a rather healthy woman: a case report.

    PubMed

    Saber, Aly

    2009-07-23

    Abscess of the spleen is a rather clinical rarity with reported mortality rate up to 47%. The timely and widespread use of imaging methods facilitates early diagnosis and guides treatment, thus improving the prognosis. Most of patients were with recognized risk factors including conditions that compromise the immune system, trauma and intravenous drug abuse in addicts. The surgical treatment by splenectomy is usually the first choice of treatment. A healthy 45-year-old woman presented to the outpatient clinic with fever, 39 degrees C together with persistent upper-left-quadrant abdominal pain. Her past medical history was free from any chronic debilitating diseases or other predisposing factors. Imaging included chest and abdominal X-ray, followed by a CT scan of the upper abdomen. Splenic abscess is an unusual and potentially life-threatening disease with a diagnostic challenge due to the nonspecific clinical picture and diagnosis confirmed based mostly on imaging studies. Multiple splenic abscesses are very rarely encountered in surgical practice with a reported high mortality rate in neglected and untreated cases. Splenectomy is a safe procedure for patients with splenic abscess.

  18. Optimizing Performance of a Microwave Salinity Mapper: STARRS L-Band Radiometer Enhancements

    DTIC Science & Technology

    2007-05-04

    Contribution Number NRL/JA/ setts at Amherst, along with Quadrant Engineering Inc. 7330-05-5313. (now ProSensing Inc.) and funding from the National...Thus, sampling schemes development of STARRS by Quadrant Engineering can be optimized for particular applications. STARRS began under Naval Research...performance to be optimized. As we show later, a draw- ture, computed as the mean temperature from four back of this approach not found in analog

  19. Photocopy of aerial photograph, Pacific Air Industries, Flight 123V, June ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of aerial photograph, Pacific Air Industries, Flight 123V, June 29, 1960 (University of California, Santa Barbara, Map and Imagery Collection) PORTION OF IRVINE RANCH SHOWING SITE CA-2275-A IN LOWER LEFT QUADRANT AND SITE CA-2275-B IN UPPER RIGHT QUADRANT (see separate photograph index for 2275-B) - Irvine Ranch Agricultural Headquarters, Carillo Tenant House, Southwest of Intersection of San Diego & Santa Ana Freeways, Irvine, Orange County, CA

  20. [Generalization of the Lotka-Volterra equation].

    PubMed

    Nazarenko, V G

    1976-01-01

    A complete qualitative study of Lotka--Volterra model with cooperative interactions in the system predator-prey is carried out. The model is as follows: (see abstract). The character of all possible stationary states is investigated in the first quadrant of the phase plane of the model variables depending on the system parameters. It is shown that for the generalized model considered unstable and stable limit cycles only of the infinite amplitude are possible in the first quadrant.

Top