Sample records for quality baseline elena

  1. Deporting Elena's Father

    ERIC Educational Resources Information Center

    Tempel, Melissa Bollow

    2010-01-01

    As a bilingual teacher in Milwaukee Public Schools, this author has seen many students deal with deportation. In this article, she shares a story of Elena, whose father was deported, that casts light on a growing crisis. She is using Elena as an example because this is "not" a unique story. It has many similarities to the experiences of…

  2. The ELENA facility

    NASA Astrophysics Data System (ADS)

    Bartmann, Wolfgang; Belochitskii, Pavel; Breuker, Horst; Butin, Francois; Carli, Christian; Eriksson, Tommy; Oelert, Walter; Ostojic, Ranko; Pasinelli, Sergio; Tranquille, Gerard

    2018-03-01

    The CERN Antiproton Decelerator (AD) provides antiproton beams with a kinetic energy of 5.3 MeV to an active user community. The experiments would profit from a lower beam energy, but this extraction energy is the lowest one possible under good conditions with the given circumference of the AD. The Extra Low Energy Antiproton ring (ELENA) is a small synchrotron with a circumference a factor of 6 smaller than the AD to further decelerate antiprotons from the AD from 5.3 MeV to 100 keV. Controlled deceleration in a synchrotron equipped with an electron cooler to reduce emittances in all three planes will allow the existing AD experiments to increase substantially their antiproton capture efficiencies and render new experiments possible. ELENA ring commissioning is taking place at present and first beams to a new experiment installed in a new experimental area are foreseen in 2017. The transfer lines from ELENA to existing experiments in the old experimental area will be installed during CERN Long Shutdown 2 (LS2) in 2019 and 2020. The status of the project and ring commissioning will be reported. This article is part of the Theo Murphy meeting issue `Antiproton physics in the ELENA era'.

  3. The AD and ELENA orbit, trajectory and intensity measurement systems

    NASA Astrophysics Data System (ADS)

    Marco-Hernández, R.; Alves, D.; Angoletta, M. E.; Marqversen, O.; Molendijk, J.; Oponowicz, E.; Ruffieux, R.; Sánchez-Quesada, J.; SØby, L.

    2017-07-01

    This paper describes the new Antiproton Decelerator (AD) orbit measurement system and the Extra Low ENergy Antiproton ring (ELENA) orbit, trajectory and intensity measurement system. The AD machine at European Organization for Nuclear Research (CERN) is presently being used to decelerate antiprotons from 3.57 GeV/c to 100 MeV/c for matter vs anti-matter comparative studies. The ELENA machine, presently under commissioning, has been designed to provide an extra deceleration stage down to 13.7 MeV/c. The AD orbit system is based on 32 horizontal and 27 vertical electrostatic Beam Position Monitor (BPM) fitted with existing low noise front-end amplifiers while the ELENA system consists of 24 \\gls{BPM}s equipped with new low-noise head amplifiers. In both systems the front-end amplifiers generate a difference (delta) and a sum (sigma) signal which are sent to the digital acquisition system, placed tens of meters away from the AD or ELENA rings, where they are digitized and further processed. The beam position is calculated by dividing the difference signal by the sum signal either using directly the raw digitized data for measuring the turn-by-turn trajectory in the ELENA system or after down-mixing the signals to baseband for the orbit measurement in both machines. The digitized sigma signal will be used in the ELENA system to calculate the bunched beam intensity and the Schottky parameters with coasting beam after passing through different signal processing chain. The digital acquisition arrangement for both systems is based on the same hardware, also used in the ELENA Low Level Radio Frequency (LLRF) system, which follows the VME Switched Serial (VXS) enhancement of the Versa Module Eurocard 64x extension (VME64x) standard and includes VITA 57 standard Field Programmable Gate Array Mezzanine Card (FMC). The digital acquisition Field Programmable Gate Array (FPGA) and Digital Signal Processor (DSP) firmware shares many common functionalities with the LLRF system but

  4. Elena: A case of dissociative identity disorder from the 1920s.

    PubMed

    Schimmenti, Adriano

    2017-01-01

    In 1930, Italian psychiatrist Giovanni Enrico Morselli described the history, diagnosis, and treatment of his patient Elena. The case of Elena has been considered in literature as one of the most remarkable cases of multiple personality ever published. In fact, before treatment, Elena showed alternating French- and Italian-speaking personalities, with the Italian personality knowing nothing of her French counterparts. After a difficult treatment involving recovered memories of incestuous attacks by her father, which were proven to be true, Elena fully recovered from her symptoms. In this article, the author presents details of the case that were not available in the international literature before. He also discusses Elena's psychological and somatoform symptoms according to a contemporary perspective on the relationally traumatic origins of dissociation and dissociative identity disorder.

  5. The BepiColombo Serena/ELENA instrument: performances and testing

    NASA Astrophysics Data System (ADS)

    Orsini, Stefano; De Angelis, Elisabetta; Selci, Stefano; Di Lellis, Andrea; Leoni, Roberto; Rispoli, Rosanna; Colasanti, Luca; Vertolli, Nello; Mura, Alessandro; Milillo, Anna; D'Alessandro, Marco; Mattioli, Francesco; Maschietti, Daniele; Brienza, Daniele; Scheer, Juergen; Wurz, Peter

    2013-04-01

    The neutral sensor ELENA (Emitted Low-Energy Neutral Atoms) for the ESA cornerstone BepiColombo mission to Mercury (in the SERENA instrument package) is a new kind of low energetic neutral atoms instrument, mostly devoted to sputtering emission from planetary surfaces, from E ~20 eV up to E~5 keV, within 1-D (4.5°x76°). ELENA is a Time of Flight instrument, based on the novel concept of ultra-sonic oscillating shutter as Start section and MCP detector with 32 discrete anodes as a direct Stop section. ELENA will monitor the emission of neutral atoms from the whole surface of Mercury allowing to investigate the interaction between the environment and the planet, the global particle loss-rate and the remote sensing of the surface properties. In particular, surface release processes are investigated by identifying particles release from the surface via solar wind-induced ion sputtering (<1eV - >100 eV) as well as Hydrogen back-scattered at hundreds eV. The results of ELENA performance test, will be presented: the innovative Shutter system (Start section) operating at requested frequencies (around 43kHz), the ion rejection capability of double deflection system, the Stop detector, the electronic boards, the validation test.

  6. BepiColombo Serena/ELENA instrument:development and testing

    NASA Astrophysics Data System (ADS)

    Orsini, S.; De Angelis, E.; Selci, S.; Di Lellis, A. M.:; Leoni, R.; Rispoli, R.; Colasanti, L.; Vertolli, N.; Scheer, J.; Mura, A.; Milillo, A.; Wurz, P.; D'Alessandro, M.; Maschietti, D.; Mattioli, F.; Cibella, S.; Brienza, D.; lo Spazio, Compagnia Generale per

    2012-04-01

    ELENA is a TOF sensor, based on a novel concept ultra-sonic oscillating shutter (Start section) which is operated at frequencies up to 50 kHz; a MCP detector is used as a Stop section. It is aimed to detect neutral atoms in the range 10 eV - 5 keV, within 70° FOV, perpendicular to the S/C orbital plane. ELENA will monitor the emission of neutral atoms from the whole surface of Mercury thanks to the spacecraft motion. The major scientific objectives are the interaction between the environment and the planet, the global particle loss-rate and the remote sensing of the surface properties. In particular, surface release processes are investigated by identifying particles release from the surface, via solar wind-induced ion sputtering (<1eV - >100 eV) as well as Hydrogen back-scattered at hundreds eV. In particular, the capability to detect non-thermal low energy neutral species is crucial for the sensor ELENA (Emitted Low-Energy Neutral Atoms), part of the package SERENA (Search for Exospheric Refilling and Emitted Natural Abundances) on board the BepiColombo mission to Mercury to be launched in 2014. The instrument is now validated and tested to reach its performances: the up-graded shutter system (Start section) has been operated for the first time with neutral atom beam and tested at high frequency, the Stop section has been calibrated investigating the region of very low energy detection efficiency, the electronics boards and the entire acquisition chain has been appointed and tested with ion beam. The first results of all the ELENA capability will be presented.

  7. Ecotourism: The Santa Elena Rainforest Project.

    ERIC Educational Resources Information Center

    Wearing, Stephen

    1993-01-01

    Describes an ecotourism project in which the community of Santa Elena, Costa Rica, are developing a rainforest reserve on government land leased permanently to the local high school. Discusses the impact of the project on the community's economy and environment. (Contains 30 references.) (MDH)

  8. Significant Silence in Elena Garro's "Los Perros"

    ERIC Educational Resources Information Center

    Burke, Jessica

    2010-01-01

    Elena Garro's one-act play "Los perros" (1958) confronts the difficult issue of sexual violence in rural Mexico, a problem that persists today. The characters struggle with the social reality of rape, alluding to the threat of sexual violence while avoiding addressing it directly. While words are granted an almost magical power in…

  9. The BepiColombo SERENA/ELENA sensor. Approaching final delivery: sensor description and recent results

    NASA Astrophysics Data System (ADS)

    Orsini, S.; Selci, S.; Di Lellis, A. M.; Mura, A.; De Angelis, E.; Milillo, A.; Leoni, R.; Dandouras, I.; Scheer, J.; Wurz, P.

    2012-04-01

    The neutral sensor ELENA (Emitted Low-Energy Neutral Atoms) for the ESA cornerstone BepiColombo mission to Mercury (in the SERENA instrument package) is a new kind of low energetic neutral atoms instrument, mostly devoted to sputtering emission from planetary surfaces, from E ~20 eV up to E~5 keV, within 1-D (4.5°x76°). ELENA is a Time-of-Flight (TOF) system, based on oscillating shutter (operated at frequencies up to 50 kHz) and mechanical gratings: the incoming neutral particles directly impinge upon the entrance with a definite timing (START) and arrive to a STOP detector after a flight path. In this way the low-energy neutral particles are directly detected, without using elements of interaction. The new results of the development of the BepiColombo SERENA/ELENA instrument are presented in the frame of the scientific items (instrument simulations, laboratory testing, etc.). In particular, the actual status of the ELENA TOF sections (shuttering system and MCPs) are reported in the light of recent testing results. The sensor performances are investigated, as well as their capability to accomplish the scientific requirements (new deflector system, shuttering functionality test, MCP efficiency, piezo driver and proximity boards, etc.).

  10. ELENA MCP detector: absolute detection efficiency for low-energy neutral atoms

    NASA Astrophysics Data System (ADS)

    Rispoli, R.; De Angelis, E.; Colasanti, L.; Vertolli, N.; Orsini, S.; Scheer, J. A.; Mura, A.; Milillo, A.; Wurz, P.; Selci, S.; Di Lellis, A. M.; Leoni, R.; D'Alessandro, M.; Mattioli, F.; Cibella, S.

    2012-09-01

    Microchannel Plates (MCP) detectors are frequently used in space instrumentation for detecting a wide range of radiation and particles. In particular, the capability to detect non-thermal low energy neutral species is crucial for the sensor ELENA (Emitted Low-Energy Neutral Atoms), part of the package SERENA (Search for Exospheric Refilling and Emitted Natural Abundances) on board the BepiColombo mission of ESA to Mercury to be launched in 2015. ELENA is a Time of Flight (TOF) sensor, based on a novel concept using an ultra-sonic oscillating shutter (Start section), which is operated at frequencies up to 50 kHz; a MCP detector is used as a Stop detector. The scientific objective of ELENA is to detect energetic neutral atoms in the range 10 eV - 5 keV, within 76° FOV, perpendicular to the S/C orbital plane. ELENA will monitor the emission of neutral atoms from the whole surface of Mercury thanks to the spacecraft motion. The major scientific objectives are the interaction between the plasma environment and the planet’s surface, the global particle loss-rate and the remote sensing of the surface properties. In particular, surface release processes are investigated by identifying particles released from the surface, via solar wind-induced ion sputtering (< 1eV - < 100 eV) as well as Hydrogen back-scattered at hundreds eV. MCP absolute detection efficiency for very low energy neutral atoms (E < 30 eV) is a crucial point for this investigation. At the MEFISTO facility of the Physical Institute of the University of Bern (CH), measurements on three different types of MCP (with and without coating) have been performed providing the detection efficiencies in the energy range 10eV - 1keV. Outcomes from such measurements are discussed here.

  11. ELENA MCP detector: absolute efficiency measurement for low energy neutral atoms

    NASA Astrophysics Data System (ADS)

    Rispoli, R.; De Angelis, E.; Colasanti, L.; Vertolli, N.; Orsini, S.; Scheer, J.; Mura, A.; Milillo, A.; Wurz, P.; Selci, S.; Di Lellis, A. M.; Leoni, R.; D'Alessandro, M.; Mattioli, F.; Cibella, S.

    2012-04-01

    MicroChannel plates (MCP) detectors are frequently used in space instrumentation for detecting a wide range of radiation and particles. In particular, the capability to detect non-thermal low energy neutral species is crucial for the sensor ELENA (Emitted Low-Energy Neutral Atoms), part of the package SERENA (Search for Exospheric Refilling and Emitted Natural Abundances) on board the BepiColombo mission to Mercury to be launched in 2014. ELENA is a TOF sensor, based on a novel concept ultra-sonic oscillating shutter (Start section)which is operated at frequencies up to 50 kHz; a MCP detector is used as a Stop section. It is aimed to detect neutral atoms in the range 10 eV - 5 keV, within 70° FOV, perpendicular to the S/C orbital plane. ELENA will monitor the emission of neutral atoms from the whole surface of Mercury thanks to the spacecraft motion. The major scientific objectives are the interaction between the environment and the planet, the global particle loss-rate and the remote sensing of the surface properties. In particular, surface release processes are investigated by identifying particles release from the surface, via solar wind-induced ion sputtering (<1eV and >100 eV) as well as Hydrogen back-scattered at hundreds eV. MCP absolute detection efficiency for very low energy neutral atoms (E< 30eV) is a crucial point not yet investigated. At the MEFISTO facility of the Physical Institute of University of Bern (CH), measurements on three different type of MCPs coating have been performed providing the behaviors of MCP detection efficiency in the range 10eV-1keV. Outcomes from such measurements are here discussed.

  12. Elena Guardincerri: Tracking muons to reduce nuclear threats and help preserve architectural treasures

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Del Mauro, Diana; Guardincerri, Elena

    When Elena Guardincerri was a physics PhD student at the University of Genova, she considered muons a nuisance. She built muon detectors to snare these secondary cosmic rays, which were interfering with her experiments to study elusive neutrinos.

  13. Low energy high angular resolution neutral atom detection by means of micro-shuttering techniques: the BepiColombo SERENA/ELENA unit development

    NASA Astrophysics Data System (ADS)

    Orsini, S.; di Lellis, A. M.; Milillo, A.; Selci, S.; Leoni, R.; Dandouras, I.

    2009-04-01

    ELENA (Emitted Low-Energy Neutral Atoms) is a Time-of-Flight (ToF) system, based on oscillating shutter (operated at frequencies up to a 100 kHz) and mechanical gratings devoted to sputtering emission from planetary surfaces, from E ~20 eV up to E ~5 keV. This new kind of low energetic neutral atoms instrument is one of the four units of the SERENA experiment for the ESA cornerstone BepiColombo mission to Mercury. The low energetic neutral particles that are likely to be detected by ELENA come primarily from ion-sputtering process, and secondarily from back-scattering and from charge exchange. ELENA will resolve intensity, velocity and direction of the incoming particle flux: the entrance of the start section (an aperture of about 1 cm2consisting of two self-standing silicon nitride (Si3N4) membranes, patterned with arrays of long and narrow openings) allows the impinging neutral particles to enter through the shuttering system with a definite timing. Particles are then flown in a ToF chamber, and finally detected by a 1-dimensional array composed by MCPs and a discrete anodes set corresponding to a Field of View (FOV) of 4.5"x76", allowing the reconstruction of both velocity and direction of the incoming events. This poster will present the new results of the ELENA development in the frame of the scientific items, instrument simulation, laboratory activity and testing. In particular, the ELENA input section and shuttering system will be reported (new deflector system, shuttering functionality test, membranes VUV optical proprieties and particle beam interactions).

  14. Low energy high angular resolution neutral atom detection by means of micro-shuttering techniques: the BepiColombo SERENA/ELENA sensor

    NASA Astrophysics Data System (ADS)

    Orsini, S.; di Lellis, A. M.; Milillo, A.; de Angelis, E.; Mura, A.; Selci, S.; Dandouras, I.; Cerulli-Irelli, P.; Leoni, R.; Mangano, V.; Massetti, S.; Mattioli, F.; Orfei, R.; Austin, C.; Medale, J.-L.; Vertolli, N.; di Giulio, D.

    2009-06-01

    The neutral sensor ELENA (Emitted Low-Energy Neutral Atoms) for the ESA cornerstone BepiColombo mission to Mercury (in the SERENA instrument package) is a new kind of low energetic neutral atoms instrument, mostly devoted to sputtering emission from planetary surfaces, from E~20 eV up to E~5 keV, within 1-D (2°×76°). ELENA is a Time-of-Flight (TOF) system, based on oscillating shutter (operated at frequencies up to a 100 kHz) and mechanical gratings: the incoming neutral particles directly impinge upon the entrance with a definite timing (START) and arrive to a STOP detector after a flight path. After a brief dissertation on the achievable scientific objectives, this paper describes the instrument, with the new design techniques approached for the neutral particles identification and the nano-techniques used for designing and manufacturing the nano-structure shuttering core of the ELENA sensor. The expected count-rates, based on the Hermean environment features, are shortly presented and discussed. Such design technologies could be fruitfully exported to different applications for planetary exploration.

  15. STS-84 Mission Specialist Elena V. Kondakova in white room

    NASA Technical Reports Server (NTRS)

    1997-01-01

    KENNEDY SPACE CENTER, FLA. -- STS-84 Mission Specialist Elena V. Kondakova prepares to enter the Space Shuttle Atlantis at Launch Pad 39A with help from white room closeout crew members. The fourth Shuttle mission of 1997 will be the sixth docking of the Space Shuttle with the Russian Space Station Mir. The commander is Charles J. Precourt. The pilot is Eileen Marie Collins. The five mission specialists are C. Michael Foale, Carlos I. Noriega, Edward Tsang Lu, Jean-Francois Clervoy of the European Space Agency and Elena V. Kondakova of the Russian Space Agency. The planned nine-day mission will include the exchange of Foale for U.S. astronaut and Mir 23 crew member Jerry M. Linenger, who has been on Mir since Jan. 15. Linenger transferred to Mir during the last docking mission, STS-81; he will return to Earth on Atlantis. Foale is slated to remain on Mir for about four months until he is replaced in September by STS-86 Mission Specialist Wendy B. Lawrence. During the five days Atlantis is scheduled to be docked with the Mir, the STS-84 crew and the Mir 23 crew, including two Russian cosmonauts, Commander Vasily Tsibliev and Flight Engineer Alexander Lazutkin, will participate in joint experiments. The STS-84 mission also will involve the transfer of more than 7,300 pounds of water, logistics and science equipment to and from the Mir. Atlantis is carrying a nearly 300-pound oxygen generator to replace one of two Mir units which have experienced malfunctions. The oxygen it generates is used for breathing by the Mir crew.

  16. Baseline requirements can hinder trades in water quality trading programs: Evidence from the Conestoga watershed.

    PubMed

    Ghosh, Gaurav; Ribaudo, Marc; Shortle, James

    2011-08-01

    The U.S. Environmental Protection Agency (USEPA) and the U.S. Department of Agriculture (USDA) are promoting point/nonpoint trading as a way of reducing the costs of meeting water quality goals. Farms can create offsets by implementing management practices such as conservation tillage, nutrient management and buffer strips. To be eligible to sell offsets or credits, farmers must first comply with baseline requirements. USEPA guidance recommends that the baseline for nonpoint sources be management practices that are consistent with the water quality goal. A farmer would not be able to create offsets until the minimum practice standards are met. An alternative baseline is those practices being implemented at the time the trading program starts, or when the farmer enters the program. The selection of the baseline affects the efficiency and equity of the trading program. It has major implications for which farmers benefit from trading, the cost of nonpoint source offsets, and ultimately the number of offsets that nonpoint sources can sell to regulated point sources. We use a simple model of the average profit-maximizing dairy farmer operating in the Conestoga watershed in Pennsylvania to evaluate the implications of baseline requirements on the cost and quantity of offsets that can be produced for sale in a water quality trading market, and which farmers benefit most from trading. Published by Elsevier Ltd.

  17. International Boundary Study. Series A. Limits in the Seas. Number 42, Straight Baselines: Ecuador.

    DTIC Science & Technology

    1972-05-23

    point a straight line to Puntilla de Santa Elena; (d) A straight line from Puntilla de Santa Elena in the direction of Cabo Blanco ( Peru ) to the...published by the U.S. Navy Oceanographic Office. 1. The seaward extension of the Colombia-Ecuador land boundary into Bahia Ancon de Sardinas is not...Comments 1-2 81 Closes Bahia Ancon de Sardinas, which is neither a historical nor juridical bay, by connecting Cabo Manglares, Colombia (1) and Punta Galera

  18. CryoSat Ice Processor: High-Level Overview of Baseline-C Data and Quality-Control

    NASA Astrophysics Data System (ADS)

    Mannan, R.; Webb, E.; Hall, A.; Bouffard, J.; Femenias, P.; Parrinello, T.; Bouffard, J.; Brockley, D.; Baker, S.; Scagliola, M.; Urien, S.

    2016-08-01

    Since April 2015, the CryoSat ice products have been generated with the new Baseline-C Instrument Processing Facilities (IPFs). This represents a major upgrade to the CryoSat ice IPFs and is the baseline for the second CryoSat Reprocessing Campaign. Baseline- C introduces major evolutions with respect to Baseline- B, most notably the release of freeboard data within the L2 SAR products, following optimisation of the SAR retracker. Additional L2 improvements include a new Arctic Mean Sea Surface (MSS) in SAR; a new tuneable land ice retracker in LRM; and a new Digital Elevation Model (DEM) in SARIn. At L1B new attitude fields have been introduced and existing datation and range biases reduced. This paper provides a high level overview of the changes and evolutions implemented at Baseline-C in order to improve CryoSat L1B and L2 data characteristics and exploitation over polar regions. An overview of the main Quality Control (QC) activities performed on operational Baseline-C products is also presented.

  19. Drawing a baseline in aesthetic quality assessment

    NASA Astrophysics Data System (ADS)

    Rubio, Fernando; Flores, M. Julia; Puerta, Jose M.

    2018-04-01

    Aesthetic classification of images is an inherently subjective task. There does not exist a validated collection of images/photographs labeled as having good or bad quality from experts. Nowadays, the closest approximation to that is to use databases of photos where a group of users rate each image. Hence, there is not a unique good/bad label but a rating distribution given by users voting. Due to this peculiarity, it is not possible to state the problem of binary aesthetic supervised classification in such a direct mode as other Computer Vision tasks. Recent literature follows an approach where researchers utilize the average rates from the users for each image, and they establish an arbitrary threshold to determine their class or label. In this way, images above the threshold are considered of good quality, while images below the threshold are seen as bad quality. This paper analyzes current literature, and it reviews those attributes able to represent an image, differentiating into three families: specific, general and deep features. Among those which have been proved more competitive, we have selected a representative subset, being our main goal to establish a clear experimental framework. Finally, once features were selected, we have used them for the full AVA dataset. We have to remark that to perform validation we report not only accuracy values, which is not that informative in this case, but also, metrics able to evaluate classification power within imbalanced datasets. We have conducted a series of experiments so that distinct well-known classifiers are learned from data. Like that, this paper provides what we could consider valuable and valid baseline results for the given problem.

  20. AEgIS at ELENA: outlook for physics with a pulsed cold antihydrogen beam

    NASA Astrophysics Data System (ADS)

    Doser, M.; Aghion, S.; Amsler, C.; Bonomi, G.; Brusa, R. S.; Caccia, M.; Caravita, R.; Castelli, F.; Cerchiari, G.; Comparat, D.; Consolati, G.; Demetrio, A.; Di Noto, L.; Evans, C.; Fanì, M.; Ferragut, R.; Fesel, J.; Fontana, A.; Gerber, S.; Giammarchi, M.; Gligorova, A.; Guatieri, F.; Haider, S.; Hinterberger, A.; Holmestad, H.; Kellerbauer, A.; Khalidova, O.; Krasnický, D.; Lagomarsino, V.; Lansonneur, P.; Lebrun, P.; Malbrunot, C.; Mariazzi, S.; Marton, J.; Matveev, V.; Mazzotta, Z.; Müller, S. R.; Nebbia, G.; Nedelec, P.; Oberthaler, M.; Pacifico, N.; Pagano, D.; Penasa, L.; Petracek, V.; Prelz, F.; Prevedelli, M.; Rienaecker, B.; Robert, J.; Røhne, O. M.; Rotondi, A.; Sandaker, H.; Santoro, R.; Smestad, L.; Sorrentino, F.; Testera, G.; Tietje, I. C.; Widmann, E.; Yzombard, P.; Zimmer, C.; Zmeskal, J.; Zurlo, N.

    2018-03-01

    The efficient production of cold antihydrogen atoms in particle traps at CERN's Antiproton Decelerator has opened up the possibility of performing direct measurements of the Earth's gravitational acceleration on purely antimatter bodies. The goal of the AEgIS collaboration is to measure the value of g for antimatter using a pulsed source of cold antihydrogen and a Moiré deflectometer/Talbot-Lau interferometer. The same antihydrogen beam is also very well suited to measuring precisely the ground-state hyperfine splitting of the anti-atom. The antihydrogen formation mechanism chosen by AEgIS is resonant charge exchange between cold antiprotons and Rydberg positronium. A series of technical developments regarding positrons and positronium (Ps formation in a dedicated room-temperature target, spectroscopy of the n=1-3 and n=3-15 transitions in Ps, Ps formation in a target at 10 K inside the 1 T magnetic field of the experiment) as well as antiprotons (high-efficiency trapping of ?, radial compression to sub-millimetre radii of mixed ? plasmas in 1 T field, high-efficiency transfer of ? to the antihydrogen production trap using an in-flight launch and recapture procedure) were successfully implemented. Two further critical steps that are germane mainly to charge exchange formation of antihydrogen-cooling of antiprotons and formation of a beam of antihydrogen-are being addressed in parallel. The coming of ELENA will allow, in the very near future, the number of trappable antiprotons to be increased by more than a factor of 50. For the antihydrogen production scheme chosen by AEgIS, this will be reflected in a corresponding increase of produced antihydrogen atoms, leading to a significant reduction of measurement times and providing a path towards high-precision measurements. This article is part of the Theo Murphy meeting issue `Antiproton physics in the ELENA era'.

  1. STS-84 M.S. Elena Kondakova at TCDT Press Briefing

    NASA Technical Reports Server (NTRS)

    1997-01-01

    STS-84 Mission Specialist Elena V. Kondakova, a cosmonaut with the Russian Space Agency, talks to news media representatives and other onlookers during Terminal Countdown Demonstration Test (TCDT) activities at Launch Pad 39A. Kondakova will be one of seven crew members on the sixth docking of the Space Shuttle with the Russian Space Station Mir. Another of the crew members, C. Michael Foale, will transfer to the space station and become a member of the Mir 23 crew, replacing U.S. astronaut Jerry M. Linenger, who will return to Earth aboard Atlantis. Foale will live and work on Mir until mid-September when his replacement is expected to arrive on the STS-86 mission. Kondakova previously lived on the Russian space station as the flight engineer of the 17th main mission on Mir from Oct. 4, 1994, to March 9, 1995. STS-84 is targeted for a May 15 liftoff.

  2. Satellite-Surface Perspectives of Air Quality and Aerosol-Cloud Effects on the Environment: An Overview of 7-SEAS BASELInE

    NASA Technical Reports Server (NTRS)

    Tsay, Si-Chee; Maring, Hal B.; Lin, Neng-Huei; Buntoung, Sumaman; Chantara, Somporn; Chuang, Hsiao-Chi; Gabriel, Philip M.; Goodloe, Colby S.; Holben, Brent N.; Hsiao, Ta-Chih; hide

    2016-01-01

    The objectives of 7-SEASBASELInE (Seven SouthEast Asian Studies Biomass-burning Aerosols and Stratocumulus Environment: Lifecycles and Interactions Experiment) campaigns in spring 2013-2015 were to synergize measurements from uniquely distributed ground-based networks (e.g., AERONET (AErosol RObotic NETwork)), MPLNET ( NASA Micro-Pulse Lidar Network)) and sophisticated platforms (e.g.,SMARTLabs (Surface-based Mobile Atmospheric Research and Testbed Laboratories), regional contributing instruments), along with satellite observations retrievals and regional atmospheric transport chemical models to establish a critically needed database, and to advance our understanding of biomass-burning aerosols and trace gases in Southeast Asia (SEA). We present a satellite-surface perspective of 7-SEASBASELInE and highlight scientific findings concerning: (1) regional meteorology of moisture fields conducive to the production and maintenance of low-level stratiform clouds over land; (2) atmospheric composition in a biomass-burning environment, particularly tracers-markers to serve as important indicators for assessing the state and evolution of atmospheric constituents; (3) applications of remote sensing to air quality and impact on radiative energetics, examining the effect of diurnal variability of boundary-layer height on aerosol loading; (4) aerosol hygroscopicity and ground-based cloud radar measurements in aerosol-cloud processes by advanced cloud ensemble models; and (5) implications of air quality, in terms of toxicity of nanoparticles and trace gases, to human health. This volume is the third 7-SEAS special issue (after Atmospheric Research, vol. 122, 2013; and Atmospheric Environment, vol. 78, 2013) and includes 27 papers published, with emphasis on air quality and aerosol-cloud effects on the environment. BASELInE observations of stratiform clouds over SEA are unique, such clouds are embedded in a heavy aerosol-laden environment and feature characteristically greater

  3. AEgIS at ELENA: outlook for physics with a pulsed cold antihydrogen beam.

    PubMed

    Doser, M; Aghion, S; Amsler, C; Bonomi, G; Brusa, R S; Caccia, M; Caravita, R; Castelli, F; Cerchiari, G; Comparat, D; Consolati, G; Demetrio, A; Di Noto, L; Evans, C; Fanì, M; Ferragut, R; Fesel, J; Fontana, A; Gerber, S; Giammarchi, M; Gligorova, A; Guatieri, F; Haider, S; Hinterberger, A; Holmestad, H; Kellerbauer, A; Khalidova, O; Krasnický, D; Lagomarsino, V; Lansonneur, P; Lebrun, P; Malbrunot, C; Mariazzi, S; Marton, J; Matveev, V; Mazzotta, Z; Müller, S R; Nebbia, G; Nedelec, P; Oberthaler, M; Pacifico, N; Pagano, D; Penasa, L; Petracek, V; Prelz, F; Prevedelli, M; Rienaecker, B; Robert, J; Røhne, O M; Rotondi, A; Sandaker, H; Santoro, R; Smestad, L; Sorrentino, F; Testera, G; Tietje, I C; Widmann, E; Yzombard, P; Zimmer, C; Zmeskal, J; Zurlo, N

    2018-03-28

    The efficient production of cold antihydrogen atoms in particle traps at CERN's Antiproton Decelerator has opened up the possibility of performing direct measurements of the Earth's gravitational acceleration on purely antimatter bodies. The goal of the AEgIS collaboration is to measure the value of g for antimatter using a pulsed source of cold antihydrogen and a Moiré deflectometer/Talbot-Lau interferometer. The same antihydrogen beam is also very well suited to measuring precisely the ground-state hyperfine splitting of the anti-atom. The antihydrogen formation mechanism chosen by AEgIS is resonant charge exchange between cold antiprotons and Rydberg positronium. A series of technical developments regarding positrons and positronium (Ps formation in a dedicated room-temperature target, spectroscopy of the n =1-3 and n =3-15 transitions in Ps, Ps formation in a target at 10 K inside the 1 T magnetic field of the experiment) as well as antiprotons (high-efficiency trapping of [Formula: see text], radial compression to sub-millimetre radii of mixed [Formula: see text] plasmas in 1 T field, high-efficiency transfer of [Formula: see text] to the antihydrogen production trap using an in-flight launch and recapture procedure) were successfully implemented. Two further critical steps that are germane mainly to charge exchange formation of antihydrogen-cooling of antiprotons and formation of a beam of antihydrogen-are being addressed in parallel. The coming of ELENA will allow, in the very near future, the number of trappable antiprotons to be increased by more than a factor of 50. For the antihydrogen production scheme chosen by AEgIS, this will be reflected in a corresponding increase of produced antihydrogen atoms, leading to a significant reduction of measurement times and providing a path towards high-precision measurements.This article is part of the Theo Murphy meeting issue 'Antiproton physics in the ELENA era'. © 2018 The Author(s).

  4. [Establishing IAQ Metrics and Baseline Measures.] "Indoor Air Quality Tools for Schools" Update #20

    ERIC Educational Resources Information Center

    US Environmental Protection Agency, 2009

    2009-01-01

    This issue of "Indoor Air Quality Tools for Schools" Update ("IAQ TfS" Update) contains the following items: (1) News and Events; (2) IAQ Profile: Establishing Your Baseline for Long-Term Success (Feature Article); (3) Insight into Excellence: Belleville Township High School District #201, 2009 Leadership Award Winner; and (4) Have Your Questions…

  5. Assessing the quality of restored images in optical long-baseline interferometry

    NASA Astrophysics Data System (ADS)

    Gomes, Nuno; Garcia, Paulo J. V.; Thiébaut, Éric

    2017-03-01

    Assessing the quality of aperture synthesis maps is relevant for benchmarking image reconstruction algorithms, for the scientific exploitation of data from optical long-baseline interferometers, and for the design/upgrade of new/existing interferometric imaging facilities. Although metrics have been proposed in these contexts, no systematic study has been conducted on the selection of a robust metric for quality assessment. This article addresses the question: what is the best metric to assess the quality of a reconstructed image? It starts by considering several metrics and selecting a few based on general properties. Then, a variety of image reconstruction cases are considered. The observational scenarios are phase closure and phase referencing at the Very Large Telescope Interferometer (VLTI), for a combination of two, three, four and six telescopes. End-to-end image reconstruction is accomplished with the MIRA software, and several merit functions are put to test. It is found that convolution by an effective point spread function is required for proper image quality assessment. The effective angular resolution of the images is superior to naive expectation based on the maximum frequency sampled by the array. This is due to the prior information used in the aperture synthesis algorithm and to the nature of the objects considered. The ℓ1-norm is the most robust of all considered metrics, because being linear it is less sensitive to image smoothing by high regularization levels. For the cases considered, this metric allows the implementation of automatic quality assessment of reconstructed images, with a performance similar to human selection.

  6. Neutral atoms facility for space sensors characterization and BepiColombo/ELENA development instrument's progresses.

    NASA Astrophysics Data System (ADS)

    de Angelis, E.; di Lellis, A. M.; Orsini, S.; Zanza, V.; Maggi, M.; Vertolli, N.; D'Amicis, R.; Tilia, B.; Sibio, A.

    2003-04-01

    An Energetic Neutral Atoms facility to test and calibrate Neutral Atoms Analyzers has been developed in the Scientific Technical Unit of Fusion at the ENEA Research Center in Frascati (Rome-Italy). In the last years a collaboration with IFSI (Interplanetary Space and Physics Institute, CNR-Rome-Italy) has allowed to use this facility for space sensors and for characterization of crucial instruments elements. The ENA beam is realized with an ion source and a neutralization cell, and allows to test any instrument in the energy range 300eV-110keV with the available masses of Hydrogen, Deuterium or Helium. At the moment, the critical elements of ELENA (Emitted Low Energy Neutral Atoms) instrument proposed for BepiColombo ESA cornerstone mission to Mercury is under development testing. The facility, its potentiality and the instrument characterization progresses are presented.

  7. CryoSat SAR/SARin Level1b products: assessment of BaselineC and improvements towards BaselineD

    NASA Astrophysics Data System (ADS)

    Scagliola, Michele; Fornari, Marco; Bouffard, Jerome; Parrinello, Tommaso

    2017-04-01

    CryoSat was launched on the 8th April 2010 and is the first European ice mission dedicated to the monitoring of precise changes in the thickness of polar ice sheets and floating sea ice. Cryosat carries an innovative radar altimeter called the Synthetic Aperture Interferometric Altimeter (SIRAL), that transmits pulses at a high pulse repetition frequency thus making the received echoes phase coherent and suitable for azimuth processing. This allows to reach a significantly improved along track resolution with respect to traditional pulse-width limited altimeters. CryoSat is the first altimetry mission operating in SAR mode and continuous improvements in the Level1 Instrument Processing Facility (IPF1) are being identified, tested and validated in order to improve the quality of the Level1b products. The current IPF, Baseline C, was released in operation in April 2015 and the second CryoSat reprocessing campaign was jointly initiated, taking benefit of the upgrade implemented in the IPF1 processing chain but also of some specific configurations for the calibration corrections. In particular, the CryoSat Level1b BaselineC products generated in the framework of the second reprocessing campaign include refined information for what concerns the mispointing angles and the calibration corrections. This poster will thus detail thus the evolutions that are currently planned for the CryoSat BaselineD SAR/SARin Level1b products and the corresponding quality improvements that are expected.

  8. Interannual Variation in Baseline Ozone on the Western Coast of North America and Its Influence on Urban Air Quality

    NASA Astrophysics Data System (ADS)

    Wigder, N. L.; Jaffe, D. A.; Lin, M.; Fiore, A. M.; Macdonald, A.; Gong, S.

    2011-12-01

    Baseline ozone (O3) has been defined as the distribution of mixing ratios from a site when it is not influenced by locally emitted pollution (McDonald-Buller et al., 2011; NRC, 2009; TF HTAP, 2007). In this study, we set out to understand the interannual variation (IAV) in baseline O3 along the western coast of North America and its influence on surface air quality in urban environments. Baseline data for this study comes from Trinidad Head, CA, Mount Bachelor, OR, Cheeka Peak, WA, Jackson Visitor Center, WA and Whistler Mountain, BC. We address four key questions:

    1. Do baseline observations on the western coast of North America exhibit similar IAV?
    2. How well can satellites identify IAV in baseline O3 along the western coast of North America?
    3. How does the baseline IAV influence urban air quality and O3 regulatory exceedance days?
    4. How well can global chemical transport models capture the IAV in baseline O3?
    We examine the deseasonalized baseline data to identify IAV in boundary layer air and free tropospheric air separately, as well as the combination of these datasets. Preliminary results show that the IAV (one sigma) in monthly mean O3 at the baseline sites ranges from 2.3-4.0 ppbv, based on data available from 2002-2010. All sites show some degree of correlation in IAV, with Pearson's correlation values of r=0.3-0.6 (p≤0.05). Using level 3 monthly averaged Tropospheric Emission Spectrometer (TES) data, we find correlations in O3 IAV with the baseline sites (r=0.4, p≤0.01). This analysis is being repeated with level 2 TES data. An analysis of the O3 IAV in urban/suburban areas near the baseline sites shows a relationship between the IAV present in the baseline sites and the IAV of these urban/suburban regions (r=0.3-0.6, p≤0.05), which can contribute to air quality regulation exceedances. We will also examine the baseline IAV with two global chemical transport models, the Canadian GEM-MACH model and the GFDL AM3

  9. The BepiColombo SERENA/ELENA unit development: a new technique to detect sputtered neutral atoms escaping from Mercury surface.

    NASA Astrophysics Data System (ADS)

    di Lellis, Andrea Maria; Selci, Stefano; de Angelis, Elisabetta; Leoni, Roberto; Milillo, Anna; Orsini, Stefano; Dandouras, Iannis

    2010-05-01

    ELENA (Emitted Low-Energy Neutral Atoms) is one of the four units of the SERENA experiment for the ESA cornerstone BepiColombo mission to Mercury. It is primarily devoted to understanding of Ion Sputtering processes and emission from planetary surfaces, particle back-scattering and Charge Exchange via neutral atoms detections in the energy range ~20 eV - 5 keV ELENA instrument is the first attempt of a new design techniques approached for the neutral particles identification in the low energy range. It is a Time-of-Flight system based on a peculiar Start section: an oscillating shutter (operated at frequencies up to a 100 kHz) and mechanical grating (two self-standing silicon nitride (Si3N4) membranes, patterned with arrays of long and narrow openings) that allows to identify the start time of the particles entering in the Time-of-Flight chamber. The Stop section at the end of the pattern is a 1-dimensional array composed by MCPs detector with discrete anodes corresponding to a Field of View of 4,5°x76°. This system allows having the determination of velocity and direction of the incoming particles. The instrument has a good capability to reject UV photons with the start section and to reject charged particle with a deflector system. In this paper the crucial parts of the instrument and test results will be described: the nano-structure membranes manufacturing, the shuttering system, the position encoder, the optical propriety of the membranes, the photon and particle test, the electronic box.

  10. Lichen bioindication of biodiversity, air quality, and climate: baseline results from monitoring in Washington, Oregon, and California.

    Treesearch

    Sarah Jovan

    2008-01-01

    Lichens are highly valued ecological indicators known for their sensitivity to a wide variety of environmental stressors like air quality and climate change. This report summarizes baseline results from the U.S. Department of Agriculture, Forest Service, Forest Inventory and Analysis (FIA) Lichen Community Indicator covering the first full cycle of data collection (...

  11. Baseline water quality and preliminary effects of artificial recharge on ground water, south-central Kansas, 1995-98

    USGS Publications Warehouse

    Ziegler, Andrew C.; Christensen, Victoria G.; Ross, Heather C.

    1999-01-01

    sites after recharge began, although concentrations remained within the range of baseline values in the Equus Beds aquifer and are considerably less than U.S. Environmental Protection Agency drinking-water criteria. However, a substantial quantity of water has not been recharged at the Sedgwick site to determine the overall effects of artificial recharge on aquifer quality. Continued monitoring is necessary to determine long-term effects at both sites. Major ion and trace element concentrations in source water and receiving water were analyzed to determine the compatibility of recharge and receiving ground water for artificial recharge. Stiff diagrams of major ions were used to show the similarity or differences between source surface water and receiving ground water. The water from both sources, for the most part, was chemically compatible to the receiving aquifer water at both recharge sites. It may be possible to decrease the monitoring frequency at the Halstead recharge site because water-quality changes in receiving water at this site are very gradual. However, real-time water-quality monitoring of surrogates needs to be site specific for the determination of chloride and atrazine. Real-time water-quality monitoring potentially can be used to more effectively manage the artificial recharge process, enabling project officials to respond more rapidly to changes in water quality.

  12. Approach for environmental baseline water sampling

    USGS Publications Warehouse

    Smith, K.S.

    2011-01-01

    Samples collected during the exploration phase of mining represent baseline conditions at the site. As such, they can be very important in forecasting potential environmental impacts should mining proceed, and can become measurements against which future changes are compared. Constituents in stream water draining mined and mineralized areas tend to be geochemically, spatially, and temporally variable, which presents challenges in collecting both exploration and baseline water-quality samples. Because short-term (daily) variations can complicate long-term trends, it is important to consider recent findings concerning geochemical variability of stream-water constituents at short-term timescales in designing sampling plans. Also, adequate water-quality information is key to forecasting potential ecological impacts from mining. Therefore, it is useful to collect baseline water samples adequate tor geochemical and toxicological modeling. This requires complete chemical analyses of dissolved constituents that include major and minor chemical elements as well as physicochemical properties (including pH, specific conductance, dissolved oxygen) and dissolved organic carbon. Applying chemical-equilibrium and appropriate toxicological models to water-quality information leads to an understanding of the speciation, transport, sequestration, bioavailability, and aquatic toxicity of potential contaminants. Insights gained from geochemical and toxicological modeling of water-quality data can be used to design appropriate mitigation and for economic planning for future mining activities.

  13. Major Element Geochemistry of Peridotites from Santa Elena Ophiolite Complex, NW Costa Rica and Their Tectonic Implications

    NASA Astrophysics Data System (ADS)

    Wright, S.; Snow, J. E.; Gazel, E.; Sisson, V.

    2010-12-01

    The Santa Elena Ophiolite Complex (SEOC) is located on the west coast of Northern Costa Rica, near the Nicaraguan border. It consists primarily of preserved oceanic crustal rocks and underlying upper mantle thrust onto an accretionary complex. The petrogenesis and tectonic origin of this complex have widely been interpreted to be either a preserved mantle portion of the Caribbean Large Igneous Province (CLIP) as it drifted between North and South America from the Galapagos hotpot into the present day Caribbean Ocean around 80 Ma or as the mantle section to the nearby Nicoya complex. Previous structural work suggests that SEOC is a supra-subduction complex, not related to the CLIP or Nicoya. Our preliminary results agree. Mantle peridotites collected from the Santa Elena Ophiolite Complex consist primarily of spinel lherzolite (61 %) with minor amounts of harzburgite and dunite (22 % and 16 % respectively). Spinel Cr# [molar Cr / (Cr+Al)*100] is widely accepted to constrain mantle partial melting and lithospheric melt stagnation. Cr# of spinels within Santa Elena lherzolites fall between 12 and 35, suggesting an extent of 3 % to 13 % partial melting. Cr# of harzburgites range from 35 to 39, suggesting 13 % to 14 % partial melting. This range of partial melting suggests only modest depletion of this exposed portion of the ancient uppermost mantle. TiO2 concentrations of the lherzolite and harzburgite range from 0.004% to 0.128%, with the exception of one sample, SE10 - 17 (0.258%), and fall within the normal melting trend for mantle peridotites. The presence of dunite indicates that melt flow and associated melt - rock reaction with the surrounding peridotite took place within this portion of the mantle. A Cr# of 84.5 from one of these dunite samples indicate that significant melt rock reaction with refractory melts took place. Such results are rarely found in mid-ocean ridge abyssal peridotite settings, and are currently found primarily in forearc tectonic settings

  14. Physical activity in Black breast cancer survivors: implications for quality of life and mood at baseline and 6-month follow-up.

    PubMed

    Diggins, Allyson D; Hearn, Lauren E; Lechner, Suzanne C; Annane, Debra; Antoni, Michael H; Whitehead, Nicole Ennis

    2017-06-01

    The present study sought to examine the influence of physical activity on quality of life and negative mood in a sample of Black breast cancer survivors to determine if physical activity (dichotomized) predicted mean differences in negative mood and quality of life in this population. Study participants include 114 women diagnosed with breast cancer (any stage of disease, any type of breast cancer) recruited to participate in an adaptive cognitive-behavioral stress management intervention. The mean body mass index of the sample at baseline was 31.39 (standard deviation = 7.17). A multivariate analysis of covariance (MANCOVA) was conducted to determine if baseline physical activity predicted mean differences in negative mood and quality of life at baseline and at follow ups while controlling for relevant covariates. A one-way MANCOVA revealed a significant multivariate effect by physical activity group for the combined dependent variables at Time 2 (post 10-week intervention), p = .039. The second one-way MANCOVA revealed a significant multivariate effect at Time 3 (6 months after Time 2), p = .034. Specifically, Black breast cancer survivors who engaged in physical activity experienced significantly lower negative mood and higher social/family well-being at Time 2 and higher spiritual and functional well-being at Times 2 and 3. Results show that baseline physical activity served protective functions for breast cancer survivors over time. Developing culturally relevant physical activity interventions specifically for Black breast cancer survivors may prove vital to improving quality of life and mood in this population. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  15. Is There any Relationship Between the Santa Elena Depression and Chicxulub Impact Crater, Northwestern Yucatan Peninsula, Mexico?

    NASA Astrophysics Data System (ADS)

    Lefticariu, L.

    2005-05-01

    The Terminal Cretaceous Chicxulub Impact Crater had a strong control on the depositional and diagenetic history of the northern Yucatan Platform during most of the Cenozoic Era. The Chicxulub Sedimentary Basin (henceforth Basin), which approximately coincides with the impact crater, is circumscribed by a concentration of karstic sinkholes known as the Ring of Cenotes. Santa Elena Depression (henceforth Depression) is the name proposed for the bowl-shaped buried feature, first contoured by geophysical studies, immediately south of the Basin, in the area where the Ticul 1 and UNAM 5 wells were drilled. Lithologic, petrographic, and biostratigraphic data on PEMEX, UNAM, and ICDP cores show that: 1) Cenozoic deposits are much thicker inside the Basin than inside the Depression, 2) in general, the Cenozoic formations from inside the Depression are the thickest among those outside the Basin, 3) variably dolomitized pelagic or outer-platform wackestone or mudstone occur both inside the Basin and Depression, 4) the age of the deeper-water sedimentary carbonate rocks is Paleocene-Eocene inside the Basin and Paleocene?-Early Eocene inside the Depression, 5) the oldest formations that crop out are of Middle Eocene age at the edge of the Basin and Early-Middle Eocene age inside the Depression, 6) saline lake deposits, that consist chiefly of anhydrite, gypsum, and fine carbonate, and also contain quartz, chert, clay, zeolite, potassium feldspar, pyrite, and fragments of wood, are present in the Cenozoic section of the UNAM 5 core between 282 and 198 m below the present land surface, 7) the dolomite, subaerial exposure features (subaerial crusts, vugs, karst, dedolomite), and vug-filling cement from the Eocene formations are more abundant inside the Depression than inside the Basin. The depositional environments that are proposed for explaining the Cenozoic facies succession within the Santa Elena Depression are: 1) deeper marine water (Paleocene?-Early Eocene), 2) relatively

  16. Earth Orientation Effects on Mobile VLBI Baselines

    NASA Technical Reports Server (NTRS)

    Allen, S. L.

    1984-01-01

    Improvements in data quality for the mobile VLBI systems have placed higher accuracy requirements on Earth orientation calibrations. Errors in these calibrations may give rise to systematic effects in the nonlength components of the baselines. Various sources of Earth orientation data were investigated for calibration of Mobile VLBI baselines. Significant differences in quality between the several available sources of UT1-UTC were found. It was shown that the JPL Kalman filtered space technology data were at least as good as any other and adequate to the needs of current Mobile VLBI systems and observing plans. For polar motion, the values from all service suffice. The effect of Earth orientation errors on the accuracy of differenced baselines was also investigated. It is shown that the effect is negligible for the current mobile systems and observing plan.

  17. Methodological Issues Surrounding the Use of Baseline Health-Related Quality of Life Data to Inform Trial-Based Economic Evaluations of Interventions Within Emergency and Critical Care Settings: A Systematic Literature Review.

    PubMed

    Dritsaki, Melina; Achana, Felix; Mason, James; Petrou, Stavros

    2017-05-01

    Trial-based cost-utility analyses require health-related quality of life data that generate utility values in order to express health outcomes in terms of quality-adjusted life years (QALYs). Assessments of baseline health-related quality of life are problematic where trial participants are incapacitated or critically ill at the time of randomisation. This review aims to identify and critique methods for handling non-availability of baseline health-related quality of life data in trial-based cost-utility analyses within emergency and critical illness settings. A systematic literature review was conducted, following PRISMA guidelines, to identify trial-based cost-utility analyses of interventions within emergency and critical care settings. Databases searched included the National Institute for Health Research (NIHR) Journals Library (1991-July 2016), Cochrane Library (all years); National Health Service (NHS) Economic Evaluation Database (all years) and Ovid MEDLINE/Embase (without time restriction). Strategies employed to handle non-availability of baseline health-related quality of life data in final QALY estimations were identified and critiqued. A total of 4224 published reports were screened, 19 of which met the study inclusion criteria (mean trial size 1670): 14 (74 %) from the UK, four (21%) from other European countries and one (5%) from India. Twelve studies (63%) were based in emergency departments and seven (37%) in intensive care units. Only one study was able to elicit patient-reported health-related quality of life at baseline. To overcome the lack of baseline data when estimating QALYs, eight studies (42%) assigned a fixed utility weight corresponding to either death, an unconscious health state or a country-specific norm to patients at baseline, four (21%) ignored baseline utilities, three (16%) applied values from another study, one (5%) generated utility values via retrospective recall and one (5%) elicited utilities from experts. A preliminary

  18. Agricultural Baseline (BL0) scenario

    DOE Data Explorer

    Davis, Maggie R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)] (ORCID:0000000181319328); Hellwinckel, Chad M [University of Tennessee] (ORCID:0000000173085058); Eaton, Laurence [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)] (ORCID:0000000312709626); Turhollow, Anthony [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)] (ORCID:0000000228159350); Brandt, Craig [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)] (ORCID:0000000214707379); Langholtz, Matthew H. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)] (ORCID:0000000281537154)

    2016-07-13

    Scientific reason for data generation: to serve as the reference case for the BT16 volume 1 agricultural scenarios. The agricultural baseline runs from 2015 through 2040; a starting year of 2014 is used. Date the data set was last modified: 02/12/2016 How each parameter was produced (methods), format, and relationship to other data in the data set: simulation was developed without offering a farmgate price to energy crops or residues (i.e., building on both the USDA 2015 baseline and the agricultural census data (USDA NASS 2014). Data generated are .txt output files by year, simulation identifier, county code (1-3109). Instruments used: POLYSYS (version POLYS2015_V10_alt_JAN22B) supplied by the University of Tennessee APAC The quality assurance and quality control that have been applied: • Check for negative planted area, harvested area, production, yield and cost values. • Check if harvested area exceeds planted area for annuals. • Check FIPS codes.

  19. Groundwater age for identification of baseline groundwater quality and impacts of land-use intensification - The National Groundwater Monitoring Programme of New Zealand

    NASA Astrophysics Data System (ADS)

    Morgenstern, Uwe; Daughney, Christopher J.

    2012-08-01

    SummaryWe identified natural baseline groundwater quality and impacts caused by land use intensification by relating groundwater chemistry with water age. Tritium, the most direct tracer for groundwater dating, including the time of water passage through the unsaturated zone, was overwhelmed over the recent decades by contamination from bomb-tritium from nuclear weapons testing in the early 1960s. In the Southern Hemisphere, this situation has changed now with the fading of the bomb-tritium, and tritium has become a tool for accurate groundwater dating. Tritium dating will become efficient also in the Northern Hemisphere over the next decade. Plotting hydrochemistry and field parameters versus groundwater age allowed us to identify those parameters that have increasing concentrations with age and are therefore from geological sources. These indicators for natural groundwater evolution are: Na, HCO3, SiO2, F, PO4, the redox-sensitive elements and compounds Fe, Mn, NH4, CH4, and pH and conductivity. In young groundwater that was recharged after the intensification of agriculture, nitrate, sulphate, CFC-11 and CFC-12, and pesticides are the most representative indicators for the impact of land-use intensification on groundwater quality, with 66% of the sites showing such an impact. Elevated concentrations of nitrate in oxic groundwater allowed us to reconstruct the timing and magnitude of the impact of land-use intensification on groundwater which in New Zealand occurred in two stages. Old pristine groundwater reflects the natural baseline quality. A transition to slightly elevated concentration due to low-intensity land-use was observed in groundwater recharged since around 1880. A sharp increase in nitrate and other agrochemicals due to high-intensity agriculture was observed in groundwater recharged since 1955. The threshold concentrations that distinguish natural baseline quality water from low-intensity land-use water, and low-intensity from high intensity land

  20. A new estimator for VLBI baseline length repeatability

    NASA Astrophysics Data System (ADS)

    Titov, O.

    2009-11-01

    The goal of this paper is to introduce a more effective technique to approximate for the “repeatability-baseline length” relationship that is used to evaluate the quality of geodetic VLBI results. Traditionally, this relationship is approximated by a quadratic function of baseline length over all baselines. The new model incorporates the mean number of observed group delays of the reference radio sources (i.e. estimated as global parameters) used in the estimation of each baseline. It is shown that the new method provides a better approximation of the “repeatability-baseline length” relationship than the traditional model. Further development of the new approach comes down to modeling the repeatability as a function of two parameters: baseline length and baseline slewing rate. Within the framework of this new approach the station vertical and horizontal uncertainties can be treated as a function of baseline length. While the previous relationship indicated that the station vertical uncertainties are generally 4-5 times larger than the horizontal uncertainties, the vertical uncertainties as determined by the new method are only larger by a factor of 1.44 over all baseline lengths.

  1. WATER QUALITY, MERCURY, AND HEAVY METAL DEPOSITION STUDIES IN BIOLOGICAL SPECIMENS AND SEDIMENTS FOR ECOLOGICAL BASELINE DATA IN THE ISLAND PARK WATERWAYS SYSTEM, 1973

    EPA Science Inventory

    The water quality, mercury, and heavy metal deposition in biological specimens from the Island Park waterways (17040202) were measured to establish ecological baseline data. Neutron activation analysis was used to identify quantitatively and qualitatively approximately 20 differ...

  2. Quality of work, well-being, and intended early retirement of older employees: baseline results from the SHARE Study.

    PubMed

    Siegrist, Johannes; Wahrendorf, Morten; von dem Knesebeck, Olaf; Jürges, Hendrik; Börsch-Supan, Axel

    2007-02-01

    Given the challenge of a high proportion of older employees who retire early from work we analyse associations of indicators of a poor psychosocial quality of work with intended premature departure from work in a large sample of older male and female employees in 10 European countries. Baseline data from the 'Survey of Health, Ageing and Retirement in Europe' (SHARE) were obtained from 3523 men and 3318 women in 10 European countries. Data on intended early retirement, four measures of well-being (self-rated health, depressive symptoms, general symptom load, and quality of life), and quality of work (effort-reward imbalance; low control at work) were obtained from structured interviews and questionnaires. Country-specific and total samples are analysed, using logistic regression analysis. Poor quality of work is significantly associated with intended early retirement. After adjustment for well-being odds ratios (OR) of effort-reward imbalance [OR 1.72 (1.43-2.08)] and low control at work [OR 1.51 (1.27-1.80)] on intended early retirement are observed. Poor quality of work and reduced well-being are independently associated with the intention to retire from work. The consistent association of a poor psychosocial quality of work with intended early retirement among older employees across all European countries under study calls for improved investments into better quality of work, in particular increased control and an appropriate balance between efforts spent and rewards received at work.

  3. Large-baseline InSAR for precise topographic mapping: a framework for TanDEM-X large-baseline data

    NASA Astrophysics Data System (ADS)

    Pinheiro, Muriel; Reigber, Andreas; Moreira, Alberto

    2017-09-01

    The global Digital Elevation Model (DEM) resulting from the TanDEM-X mission provides information about the world topography with outstanding precision. In fact, performance analysis carried out with the already available data have shown that the global product is well within the requirements of 10 m absolute vertical accuracy and 2 m relative vertical accuracy for flat to moderate terrain. The mission's science phase took place from October 2014 to December 2015. During this phase, bistatic acquisitions with across-track separation between the two satellites up to 3.6 km at the equator were commanded. Since the relative vertical accuracy of InSAR derived elevation models is, in principle, inversely proportional to the system baseline, the TanDEM-X science phase opened the doors for the generation of elevation models with improved quality with respect to the standard product. However, the interferometric processing of the large-baseline data is troublesome due to the increased volume decorrelation and very high frequency of the phase variations. Hence, in order to fully profit from the increased baseline, sophisticated algorithms for the interferometric processing, and, in particular, for the phase unwrapping have to be considered. This paper proposes a novel dual-baseline region-growing framework for the phase unwrapping of the large-baseline interferograms. Results from two experiments with data from the TanDEM-X science phase are discussed, corroborating the expected increased level of detail of the large-baseline DEMs.

  4. Baseline Quality of Life and Risk of Stroke in the ALLHAT Study (Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial).

    PubMed

    Shams, Tanzila; Auchus, Alexander P; Oparil, Suzanne; Wright, Clinton B; Wright, Jackson; Furlan, Anthony J; Sila, Cathy A; Davis, Barry R; Pressel, Sara; Yamal, Jose-Miguel; Einhorn, Paula T; Lerner, Alan J

    2017-11-01

    The visual analogue scale is a self-reported, validated tool to measure quality of life (QoL). Our purpose was to determine whether baseline QoL predicted strokes in the ALLHAT study (Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial) and evaluate determinants of poststroke change in QoL. In the ALLHAT study, among the 33 357 patients randomized to treatment arms, 1525 experienced strokes; 1202 (79%) strokes were nonfatal. This study cohort includes 32 318 (97%) subjects who completed the baseline visual analogue scale QoL estimate. QoL was measured on a visual analogue scale and adjusted using a Torrance transformation (transformed QoL [TQoL]). Kaplan-Meier curves and adjusted proportional hazards analyses were used to estimate the effect of TQoL on the risk of stroke, on a continuous scale (0-1) and by quartiles (≤0.81, >0.81≤0.89, >0.89≤0.95, >0.95). We analyzed the change from baseline to first poststroke TQoL using adjusted linear regression. After adjusting for multiple stroke risk factors, the hazard ratio for stroke events for baseline TQoL was 0.93 (95% confidence interval, 0.89-0.98) per 0.1 U increase. The lowest baseline TQoL quartile had a 20% increased stroke risk (hazard ratio=1.20 [95% confidence interval, 1.00-1.44]) compared with the reference highest quartile TQoL. Poststroke TQoL change was significant within all treatment groups ( P ≤0.001). Multivariate regression analysis revealed that baseline TQoL was the strongest predictor of poststroke TQoL with similar results for the untransformed QoL. The lowest baseline TQoL quartile had a 20% higher stroke risk than the highest quartile. Baseline TQoL was the only factor that predicted poststroke change in TQoL. URL: http://www.clinicaltrials.gov. Unique identifier: NCT00000542. © 2017 American Heart Association, Inc.

  5. Baseline utilization of breast radiotherapy before institution of the Medicare practice quality reporting initiative.

    PubMed

    Smith, Benjamin D; Smith, Grace L; Roberts, Kenneth B; Buchholz, Thomas A

    2009-08-01

    In 2007, Medicare implemented the Physician Quality Reporting Initiative (PQRI), which provides financial incentives to physicians who report their performance on certain quality measures. PQRI measure #74 recommends radiotherapy for patients treated with conservative surgery (CS) for invasive breast cancer. As a first step in evaluating the potential impact of this measure, we assessed baseline use of radiotherapy among women diagnosed with invasive breast cancer before implementation of PQRI. Using the SEER-Medicare data set, we identified women aged 66-70 diagnosed with invasive breast cancer and treated with CS between 2000 and 2002. Treatment with radiotherapy was determined using SEER and claims data. Multivariate logistic regression tested whether receipt of radiotherapy varied significantly across clinical, pathologic, and treatment covariates. Of 3,674 patients, 94% (3,445) received radiotherapy. In adjusted analysis, the presence of comorbid illness (odds ratio [OR] 1.69; 95% confidence interval [CI], 1.19-2.42) and unmarried marital status were associated with omission of radiotherapy (OR 1.65; 95% CI, 1.22-2.20). In contrast, receipt of chemotherapy was protective against omission of radiotherapy (OR 0.25; 95% CI, 0.16-0.38). Race and geographic region did not correlate with radiotherapy utilization. Utilization of radiotherapy following CS was high for patients treated before institution of PQRI, suggesting that at most 6% of patients could benefit from measure #74. Further research is needed to determine whether institution of PQRI will affect radiotherapy utilization.

  6. A method to establish seismic noise baselines for automated station assessment

    USGS Publications Warehouse

    McNamara, D.E.; Hutt, C.R.; Gee, L.S.; Benz, H.M.; Buland, R.P.

    2009-01-01

    We present a method for quantifying station noise baselines and characterizing the spectral shape of out-of-nominal noise sources. Our intent is to automate this method in order to ensure that only the highest-quality data are used in rapid earthquake products at NEIC. In addition, the station noise baselines provide a valuable tool to support the quality control of GSN and ANSS backbone data and metadata. The procedures addressed here are currently in development at the NEIC, and work is underway to understand how quickly changes from nominal can be observed and used within the NEIC processing framework. The spectral methods and software used to compute station baselines and described herein (PQLX) can be useful to both permanent and portable seismic stations operators. Applications include: general seismic station and data quality control (QC), evaluation of instrument responses, assessment of near real-time communication system performance, characterization of site cultural noise conditions, and evaluation of sensor vault design, as well as assessment of gross network capabilities (McNamara et al. 2005). Future PQLX development plans include incorporating station baselines for automated QC methods and automating station status report generation and notification based on user-defined QC parameters. The PQLX software is available through the USGS (http://earthquake. usgs.gov/research/software/pqlx.php) and IRIS (http://www.iris.edu/software/ pqlx/).

  7. SERENA: a suite of four instruments (ELENA, STROFIO, PICAM and MIPA) on board BepiColombo-MPO for particle detection in the Hermean Environment

    NASA Astrophysics Data System (ADS)

    Milillo, Anna; Livi, Stefano; Orsini, Stefano; Torkar, Klaus; Barabash, Stas; Milillo, Anna; Wurz, Peter; di Lellis, Andrea Maria; Kallio, Esa

    SERENA (‘Search for Exospheric Refilling and Emitted Natural Abundances') is an instrument package that will fly on board the BepiColombo/Mercury Planetary Orbiter (MPO); it will investigate the Mercury's complex particle environment that surrounds the planet. Such an environment is composed by thermal and directional neutral atoms (exosphere) originating via surface release and charge-exchange processes, and by ionized particles originated through photo-ionization and again by surface release processes. In order to accomplish the scientific goals, in-situ analysis of the environmental elements is necessary, and for such a purpose the SERENA instrument shall include four units: two Neutral Particle Analyzers (ELENA and STROFIO) and two Ion Spectrometers (MIPA and PICAM). The scientific merit of SERENA is presented, and the basic characteristics of the four units are described, with a focus on novel technological aspects.

  8. Improved Topographic Mapping Through Multi-Baseline SAR Interferometry with MAP Estimation

    NASA Astrophysics Data System (ADS)

    Dong, Yuting; Jiang, Houjun; Zhang, Lu; Liao, Mingsheng; Shi, Xuguo

    2015-05-01

    There is an inherent contradiction between the sensitivity of height measurement and the accuracy of phase unwrapping for SAR interferometry (InSAR) over rough terrain. This contradiction can be resolved by multi-baseline InSAR analysis, which exploits multiple phase observations with different normal baselines to improve phase unwrapping accuracy, or even avoid phase unwrapping. In this paper we propose a maximum a posteriori (MAP) estimation method assisted by SRTM DEM data for multi-baseline InSAR topographic mapping. Based on our method, a data processing flow is established and applied in processing multi-baseline ALOS/PALSAR dataset. The accuracy of resultant DEMs is evaluated by using a standard Chinese national DEM of scale 1:10,000 as reference. The results show that multi-baseline InSAR can improve DEM accuracy compared with single-baseline case. It is noteworthy that phase unwrapping is avoided and the quality of multi-baseline InSAR DEM can meet the DTED-2 standard.

  9. Geochemical baseline studies of soil in Finland

    NASA Astrophysics Data System (ADS)

    Pihlaja, Jouni

    2017-04-01

    The soil element concentrations regionally vary a lot in Finland. Mostly this is caused by the different bedrock types, which are reflected in the soil qualities. Geological Survey of Finland (GTK) is carrying out geochemical baseline studies in Finland. In the previous phase, the research is focusing on urban areas and mine environments. The information can, for example, be used to determine the need for soil remediation, to assess environmental impacts or to measure the natural state of soil in industrial areas or mine districts. The field work is done by taking soil samples, typically at depth between 0-10 cm. Sampling sites are chosen to represent the most vulnerable areas when thinking of human impacts by possible toxic soil element contents: playgrounds, day-care centers, schools, parks and residential areas. In the mine districts the samples are taken from the areas locating outside the airborne dust effected areas. Element contents of the soil samples are then analyzed with ICP-AES and ICP-MS, Hg with CV-AAS. The results of the geochemical baseline studies are published in the Finnish national geochemical baseline database (TAPIR). The geochemical baseline map service is free for all users via internet browser. Through this map service it is possible to calculate regional soil baseline values using geochemical data stored in the map service database. Baseline data for 17 elements in total is provided in the map service and it can be viewed on the GTK's web pages (http://gtkdata.gtk.fi/Tapir/indexEN.html).

  10. A long baseline global stereo matching based upon short baseline estimation

    NASA Astrophysics Data System (ADS)

    Li, Jing; Zhao, Hong; Li, Zigang; Gu, Feifei; Zhao, Zixin; Ma, Yueyang; Fang, Meiqi

    2018-05-01

    In global stereo vision, balancing the matching efficiency and computing accuracy seems to be impossible because they contradict each other. In the case of a long baseline, this contradiction becomes more prominent. In order to solve this difficult problem, this paper proposes a novel idea to improve both the efficiency and accuracy in global stereo matching for a long baseline. In this way, the reference images located between the long baseline image pairs are firstly chosen to form the new image pairs with short baselines. The relationship between the disparities of pixels in the image pairs with different baselines is revealed by considering the quantized error so that the disparity search range under the long baseline can be reduced by guidance of the short baseline to gain matching efficiency. Then, the novel idea is integrated into the graph cuts (GCs) to form a multi-step GC algorithm based on the short baseline estimation, by which the disparity map under the long baseline can be calculated iteratively on the basis of the previous matching. Furthermore, the image information from the pixels that are non-occluded under the short baseline but are occluded for the long baseline can be employed to improve the matching accuracy. Although the time complexity of the proposed method depends on the locations of the chosen reference images, it is usually much lower for a long baseline stereo matching than when using the traditional GC algorithm. Finally, the validity of the proposed method is examined by experiments based on benchmark datasets. The results show that the proposed method is superior to the traditional GC method in terms of efficiency and accuracy, and thus it is suitable for long baseline stereo matching.

  11. Current discharge management of acute coronary syndromes: baseline results from a national quality improvement initiative.

    PubMed

    Wai, A; Pulver, L K; Oliver, K; Thompson, A

    2012-05-01

    Evidence-practice gaps exist in the continuum of care for patients with acute coronary syndromes (ACS), particularly at hospital discharge. We aimed to describe the methodology and baseline results of the Discharge Management of Acute Coronary Syndromes (DMACS) project, focusing on the prescription of guideline-recommended medications, referral to cardiac rehabilitation and communication between the hospital, patient and their primary healthcare professionals. DMACS employed Drug Use Evaluation methodology involving data collection, evaluation and feedback, and targeted educational interventions. Adult patients with ACS discharged during a 4-month period were eligible to participate. Data were collected (maximum 50 patients) at each site through an inpatient medical record review, a general practitioner (GP) postal/fax survey conducted 14 days post discharge and a patient telephone survey 3 months post discharge. Forty-nine hospitals participated in the audit recruiting 1545 patients. At discharge, 57% of patients were prescribed a combination of antiplatelet agent(s), beta-blocker, statin and angiotensin-converting enzyme inhibitor and/or angiotensin II-antagonist. At 3 months post discharge, 48% of patients reported using the same combination. Some 67% of patients recalled being referred to cardiac rehabilitation; of these, 33% had completed the programme. In total, 83% of patients had a documented ACS management plan at discharge. Of these, 90% included a medication list, 56% a chest pain action plan and 54% risk factor modification advice. Overall, 65% of GPs rated the quality of information received in the discharge summary as 'very good' to 'excellent'. The findings of our baseline audit showed that despite the robust evidence base and availability of national guidelines, the management of patients with ACS can be improved. These findings will inform a multifaceted intervention strategy to improve adherence to guidelines for the discharge management of

  12. 40 CFR 74.20 - Data for baseline and alternative baseline.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 17 2012-07-01 2012-07-01 false Data for baseline and alternative... PROGRAMS (CONTINUED) SULFUR DIOXIDE OPT-INS Allowance Calculations for Combustion Sources § 74.20 Data for baseline and alternative baseline. (a) Acceptable data. (1) The designated representative of a combustion...

  13. The hELENa project - II. Abundance distribution trends of early-type galaxies: from dwarfs to giants

    NASA Astrophysics Data System (ADS)

    Sybilska, A.; Kuntschner, H.; van de Ven, G.; Vazdekis, A.; Falcón-Barroso, J.; Peletier, R. F.; Lisker, T.

    2018-06-01

    In this second paper of The role of Environment in shaping Low-mass Early-type Nearby galaxies (hELENa) series we study [Mg/Fe] abundance distribution trends of early-type galaxies (ETGs) observed with the Spectrographic Areal Unit for Research on Optical Nebulae integral field unit, spanning a wide range in mass and local environment densities: 20 low-mass early types (dEs) of Sybilska et al. and 258 massive early types (ETGs) of the ATLAS3D project, all homogeneously reduced and analysed. We show that the [Mg/Fe] ratios scale with velocity dispersion (σ) at fixed [Fe/H] and that they evolve with [Fe/H] along similar paths for all early types, grouped in bins of increasing local and global σ, as well as the second velocity moment Vrms, indicating a common inside-out formation pattern. We then place our dEs on the [Mg/Fe] versus [Fe/H] diagram of Local Group galaxies and show that dEs occupy the same region and show a similar trend line slope in the diagram as the high-metallicity stars of the Milky Way and the Large Magellanic Cloud. This finding extends the similar trend found for dwarf spheroidal versus dwarf irregular galaxies and supports the notion that dEs have evolved from late-type galaxies that have lost their gas at a point of their evolution, which likely coincided with them entering denser environments.

  14. Stability analysis of geomagnetic baseline data obtained at Cheongyang observatory in Korea

    NASA Astrophysics Data System (ADS)

    Amran, Shakirah M.; Kim, Wan-Seop; Cho, Heh Ree; Park, Po Gyu

    2017-07-01

    The stability of baselines produced by Cheongyang (CYG) observatory from the period of 2014 to 2016 is analysed. Step heights of higher than 5 nT were found in H and Z components in 2014 and 2015 due to magnetic noise in the absolute-measurement hut. In addition, a periodic modulation behaviour observed in the H and Z baseline curves was related to annual temperature variation of about 20 °C in the fluxgate magnetometer hut. Improvement in data quality was evidenced by a small dispersion between successive measurements from June 2015 to the end of 2016. Moreover, the baseline was also improved by correcting the discontinuity in the H and Z baselines.

  15. SERENA: A suite of four instruments (ELENA, STROFIO, PICAM and MIPA) on board BepiColombo-MPO for particle detection in the Hermean environment

    NASA Astrophysics Data System (ADS)

    Orsini, S.; Livi, S.; Torkar, K.; Barabash, S.; Milillo, A.; Wurz, P.; di Lellis, A. M.; Kallio, E.; The Serena Team

    2010-01-01

    'Search for Exospheric Refilling and Emitted Natural Abundances' (SERENA) is an instrument package that will fly on board the BepiColombo/Mercury Planetary Orbiter (MPO). It will investigate Mercury's complex particle environment that is composed of thermal and directional neutral atoms (exosphere) caused by surface release and charge-exchange processes, and of ionized particles caused by photo-ionization of neutrals as well by charge exchange and surface release processes. In order to investigate the structure and dynamics of the environment, an in-situ analysis of the key neutral and charged components is necessary, and for this purpose the SERENA instrument shall include four units: two neutral particle analyzers (Emitted Low Energy Neutral Atoms (ELENA) sensor and Start from a Rotating FIeld mass spectrometer (STROFIO)) and two ion spectrometers (Miniature Ion Precipitation Analyzer (MIPA) and Planetary Ion Camera (PICAM)). The scientific merits of SERENA are presented, and the basic characteristics of the four units are described, with a focus on novel technological aspects.

  16. Psychosocial job quality, mental health, and subjective wellbeing: a cross-sectional analysis of the baseline wave of the Australian Longitudinal Study on Male Health.

    PubMed

    LaMontagne, Anthony D; Milner, Allison; Krnjacki, Lauren; Schlichthorst, Marisa; Kavanagh, Anne; Page, Kathryn; Pirkis, Jane

    2016-10-31

    Employment status and working conditions are strong determinants of male health, and are therefore an important focus in the Australian Longitudinal Study on Male Health (Ten to Men). In this paper, we describe key work variables included in Ten to Men, and present analyses relating psychosocial job quality to mental health and subjective wellbeing at baseline. A national sample of males aged 10 to 55 years residing in private dwellings was drawn using a stratified multi-stage cluster random sample design. Data were collected between October 2013 and July 2014 for a cohort of 15,988 males, representing a response fraction of 35 %. This analysis was restricted to 18-55 year old working age participants (n = 13,456). Work-related measures included employment status, and, for those who were employed, a number of working conditions including an ordinal scale of psychosocial job quality (presence of low job control, high demand and complexity, high job insecurity, and low fairness of pay), and working time-related stressors such as long working hours and night shift work. Associations between psychosocial job quality and two outcome measures, mental ill-health and subjective wellbeing, were assessed using multiple linear regression. The majority of participants aged 18-55 years were employed at baseline (85.6 %), with 8.4 % unemployed and looking for work, and 6.1 % not in the labour force. Among employed participants, there was a high prevalence of long working hours (49.9 % reported working more than 40 h/week) and night shift work (23.4 %). Psychosocial job quality (exposure to 0/1/2/3+ job stressors) prevalence was 36 %/ 37 %/ 20 %/ and 7 % of the working respondents. There was a dose-response relationship between psychosocial job quality and each of the two outcome measures of mental health and subjective wellbeing after adjusting for potential confounders, with higher magnitude associations between psychosocial job quality and subjective wellbeing

  17. Methane Dynamics in a Tropical Serpentinizing Environment: The Santa Elena Ophiolite, Costa Rica

    PubMed Central

    Crespo-Medina, Melitza; Twing, Katrina I.; Sánchez-Murillo, Ricardo; Brazelton, William J.; McCollom, Thomas M.; Schrenk, Matthew O.

    2017-01-01

    Uplifted ultramafic rocks represent an important vector for the transfer of carbon and reducing power from the deep subsurface into the biosphere and potentially support microbial life through serpentinization. This process has a strong influence upon the production of hydrogen and methane, which can be subsequently consumed by microbial communities. The Santa Elena Ophiolite (SEO) on the northwestern Pacific coast of Costa Rica comprises ~250 km2 of ultramafic rocks and mafic associations. The climatic conditions, consisting of strongly contrasting wet and dry seasons, make the SEO a unique hydrogeological setting, where water-rock reactions are enhanced by large storm events (up to 200 mm in a single storm). Previous work on hyperalkaline spring fluids collected within the SEO has identified the presence of microorganisms potentially involved in hydrogen, methane, and methanol oxidation (such as Hydrogenophaga, Methylobacterium, and Methylibium spp., respectively), as well as the presence of methanogenic Archaea (such as Methanobacterium). Similar organisms have also been documented at other serpentinizing sites, however their functions have not been confirmed. SEO's hyperalkaline springs have elevated methane concentrations, ranging from 145 to 900 μM, in comparison to the background concentrations (<0.3 μM). The presence and potential activity of microorganisms involved in methane cycling in serpentinization-influenced fluids from different sites within the SEO were investigated using molecular, geochemical, and modeling approaches. These results were combined to elucidate the bioenergetically favorable methane production and/or oxidation reactions in this tropical serpentinizing environment. The hyperalkaline springs at SEO contain a greater proportion of Archaea and methanogens than has been detected in any terrestrial serpentinizing system. Archaea involved in methanogenesis and anaerobic methane oxidation accounted from 40 to 90% of total archaeal

  18. Methane Dynamics in a Tropical Serpentinizing Environment: The Santa Elena Ophiolite, Costa Rica.

    PubMed

    Crespo-Medina, Melitza; Twing, Katrina I; Sánchez-Murillo, Ricardo; Brazelton, William J; McCollom, Thomas M; Schrenk, Matthew O

    2017-01-01

    Uplifted ultramafic rocks represent an important vector for the transfer of carbon and reducing power from the deep subsurface into the biosphere and potentially support microbial life through serpentinization. This process has a strong influence upon the production of hydrogen and methane, which can be subsequently consumed by microbial communities. The Santa Elena Ophiolite (SEO) on the northwestern Pacific coast of Costa Rica comprises ~250 km 2 of ultramafic rocks and mafic associations. The climatic conditions, consisting of strongly contrasting wet and dry seasons, make the SEO a unique hydrogeological setting, where water-rock reactions are enhanced by large storm events (up to 200 mm in a single storm). Previous work on hyperalkaline spring fluids collected within the SEO has identified the presence of microorganisms potentially involved in hydrogen, methane, and methanol oxidation (such as Hydrogenophaga, Methylobacterium , and Methylibium spp., respectively), as well as the presence of methanogenic Archaea (such as Methanobacterium ). Similar organisms have also been documented at other serpentinizing sites, however their functions have not been confirmed. SEO's hyperalkaline springs have elevated methane concentrations, ranging from 145 to 900 μM, in comparison to the background concentrations (<0.3 μM). The presence and potential activity of microorganisms involved in methane cycling in serpentinization-influenced fluids from different sites within the SEO were investigated using molecular, geochemical, and modeling approaches. These results were combined to elucidate the bioenergetically favorable methane production and/or oxidation reactions in this tropical serpentinizing environment. The hyperalkaline springs at SEO contain a greater proportion of Archaea and methanogens than has been detected in any terrestrial serpentinizing system. Archaea involved in methanogenesis and anaerobic methane oxidation accounted from 40 to 90% of total archaeal

  19. Baseline assessment of groundwater quality in Pike County, Pennsylvania, 2015

    USGS Publications Warehouse

    Senior, Lisa A.; Cravotta, Charles A.

    2017-12-29

    The Devonian-age Marcellus Shale and the Ordovician-age Utica Shale, which have the potential for natural gas development, underlie Pike County and neighboring counties in northeastern Pennsylvania. In 2015, the U.S. Geological Survey, in cooperation with the Pike County Conservation District, conducted a study that expanded on a previous more limited 2012 study to assess baseline shallow groundwater quality in bedrock aquifers in Pike County prior to possible extensive shale-gas development. Seventy-nine water wells ranging in depths from 80 to 610 feet were sampled during June through September 2015 to provide data on the presence of methane and other aspects of existing groundwater quality in the various bedrock geologic units throughout the county, including concentrations of inorganic constituents commonly present at low values in shallow, fresh groundwater but elevated in brines associated with fluids extracted from geologic formations during shale-gas development. All groundwater samples collected in 2015 were analyzed for bacteria, dissolved and total major ions, nutrients, selected dissolved and total inorganic trace constituents (including metals and other elements), radon-222, gross alpha- and gross beta-particle activity, dissolved gases (methane, ethane, and propane), and, if sufficient methane was present, the isotopic composition of methane. Additionally, samples from 20 wells distributed throughout the county were analyzed for selected man-made volatile organic compounds, and samples from 13 wells where waters had detectable gross alpha activity were analyzed for radium-226 on the basis of relatively elevated gross alpha-particle activity.Results of the 2015 study show that groundwater quality generally met most drinking-water standards for constituents and properties included in analyses, but groundwater samples from some wells had one or more constituents or properties, including arsenic, iron, manganese, pH, bacteria, sodium, chloride, sulfate

  20. Baseline assessment of groundwater quality in Wayne County, Pennsylvania, 2014

    USGS Publications Warehouse

    Senior, Lisa A.; Cravotta, III, Charles A.; Sloto, Ronald A.

    2016-06-30

    The Devonian-age Marcellus Shale and the Ordovician-age Utica Shale, geologic formations which have potential for natural gas development, underlie Wayne County and neighboring counties in northeastern Pennsylvania. In 2014, the U.S. Geological Survey, in cooperation with the Wayne Conservation District, conducted a study to assess baseline shallow groundwater quality in bedrock aquifers in Wayne County prior to potential extensive shale-gas development. The 2014 study expanded on previous, more limited studies that included sampling of groundwater from 2 wells in 2011 and 32 wells in 2013 in Wayne County. Eighty-nine water wells were sampled in summer 2014 to provide data on the presence of methane and other aspects of existing groundwater quality throughout the county, including concentrations of inorganic constituents commonly present at low levels in shallow, fresh groundwater but elevated in brines associated with fluids extracted from geologic formations during shale-gas development. Depths of sampled wells ranged from 85 to 1,300 feet (ft) with a median of 291 ft. All of the groundwater samples collected in 2014 were analyzed for bacteria, major ions, nutrients, selected inorganic trace constituents (including metals and other elements), radon-222, gross alpha- and gross beta-particle activity, selected man-made organic compounds (including volatile organic compounds and glycols), dissolved gases (methane, ethane, and propane), and, if sufficient methane was present, the isotopic composition of methane.Results of the 2014 study show that groundwater quality generally met most drinking-water standards, but some well-water samples had one or more constituents or properties, including arsenic, iron, pH, bacteria, and radon-222, that exceeded primary or secondary maximum contaminant levels (MCLs). Arsenic concentrations were higher than the MCL of 10 micrograms per liter (µg/L) in 4 of 89 samples (4.5 percent) with concentrations as high as 20 µg/L; arsenic

  1. ES Review: Selections from 2009 and 2010

    ERIC Educational Resources Information Center

    Smiles, Robin, Ed.

    2010-01-01

    This fourth edition of the "ES Review" brings together, in one setting, some of the best work from 2009-10. It features: (1) Teacher Quality (Teachers at Work: Improving Teacher Quality Through School Design (Elena Silva); Understanding Teachers Contracts (Andrew J. Rotherham); How Teachers Unions Lost the Media (Richard Whitmire and…

  2. Clinical governance is "ACE"--using the EFQM excellence model to support baseline assessment.

    PubMed

    Holland, K; Fennell, S

    2000-01-01

    The introduction of clinical governance in the "new NHS" means that National Health Service (NHS) organisations are now accountable for the quality of the services they provide to their local communities. As part of the implementation of clinical governance in the NHS, Trusts and health authorities had to complete a baseline assessment of their capability and capacity by September 1999. Describes one Trust's approach to developing and implementing its baseline assessment tool, based upon its existing use of the European Foundation for Quality Management (EFQM) Excellence Model. An initial review of the process suggests that the model provides an adaptable framework for the development of a comprehensive and practical assessment tool and that self-assessment ensures ownership of action plans at service level.

  3. Few millimeter precision for baselines in the California Permanent GPS Geodetic Array

    NASA Technical Reports Server (NTRS)

    Lindqwister, Ulf J.; Zumberge, James F.; Webb, Frank H.; Blewitt, Geoffrey

    1991-01-01

    Geodetic measurements with Rogue GPS receivers from sites in the California Permanent GPS geodetic Array (PGGA) have been analyzed using the GIPSY orbit-determination and baseline-estimation software. Based on an unbiased selection of 23 daily measurements spanning 8 months, the LF contributions to the long-term repeatabilities of baseline measurements are approximately 5, 3, and 8 mm for the east, north, and vertical components. Short-term contributions to the long-term repeatabilities were evaluated by examining data from the week of October 21, 1990, which showed the lowest short-term scatter. For this week, daily repeatabilities of 2-3 mm in the horizontal and 4 mm in the vertical have been achieved for the 172-km JPL-Pinyon baseline, consistent with carrier phase date noise of about 6 mm. High quality (less than about 5 mm) repeatabilities have been achieved for all components of the other baselines as well.

  4. An Analysis Method for Superconducting Resonator Parameter Extraction with Complex Baseline Removal

    NASA Technical Reports Server (NTRS)

    Cataldo, Giuseppe

    2014-01-01

    A new semi-empirical model is proposed for extracting the quality (Q) factors of arrays of superconducting microwave kinetic inductance detectors (MKIDs). The determination of the total internal and coupling Q factors enables the computation of the loss in the superconducting transmission lines. The method used allows the simultaneous analysis of multiple interacting discrete resonators with the presence of a complex spectral baseline arising from reflections in the system. The baseline removal allows an unbiased estimate of the device response as measured in a cryogenic instrumentation setting.

  5. Impact of Quality Improvement Educational Interventions on Documented Adherence to Quality Measures for Adults with Crohn's Disease.

    PubMed

    Greene, Laurence; Sapir, Tamar; Moreo, Kathleen; Carter, Jeffrey D; Patel, Barry; Higgins, Peter D R

    2015-09-01

    In recent years, leading organizations in inflammatory bowel disease (IBD) have developed quality measures for the care of adults with Crohn's disease or ulcerative colitis. We used chart audits to assess the impact of quality improvement educational activities on documented adherence to Physician Quality Reporting System measures for IBD. Twenty community-based gastroenterologists were recruited to participate in baseline chart audits (n = 200), a series of 4 accredited educational activities with feedback, and follow-up chart audits (n = 200). Trained abstractors reviewed randomly selected charts of adults with moderate or severe Crohn's disease. The charts were retrospectively abstracted for physicians' documented performance of the 2013 Physician Quality Reporting System IBD quality measures. We compared the physicians' baseline and posteducation rates of documented adherence with 10 of these measures. In a secondary analysis, we compared preeducation with posteducation difference scores of low-performing physicians, those whose baseline documentation rates were in the lowest quartile, and the rest of the cohort. At baseline, documentation of mean provider-level adherence to the 10 quality measures ranged from 3% to 98% (grand mean = 35.8%). In the overall analysis, baseline and posteducation rates of documented adherence did not differ significantly for any of the measures. However, for 4 measures, preeducation to posteducation difference scores were significantly greater among low performers than physicians in the highest 3 quartiles. The results of this preliminary pragmatic study indicate that quality improvement education affords the potential to improve adherence to Physician Quality Reporting System quality measures for IBD among low-performing gastroenterologists.

  6. Item response theory analysis of the mechanics baseline test

    NASA Astrophysics Data System (ADS)

    Cardamone, Caroline N.; Abbott, Jonathan E.; Rayyan, Saif; Seaton, Daniel T.; Pawl, Andrew; Pritchard, David E.

    2012-02-01

    Item response theory is useful in both the development and evaluation of assessments and in computing standardized measures of student performance. In item response theory, individual parameters (difficulty, discrimination) for each item or question are fit by item response models. These parameters provide a means for evaluating a test and offer a better measure of student skill than a raw test score, because each skill calculation considers not only the number of questions answered correctly, but the individual properties of all questions answered. Here, we present the results from an analysis of the Mechanics Baseline Test given at MIT during 2005-2010. Using the item parameters, we identify questions on the Mechanics Baseline Test that are not effective in discriminating between MIT students of different abilities. We show that a limited subset of the highest quality questions on the Mechanics Baseline Test returns accurate measures of student skill. We compare student skills as determined by item response theory to the more traditional measurement of the raw score and show that a comparable measure of learning gain can be computed.

  7. Environmental baseline study of the Huron River Watershed, Baraga and Marquette Counties, Michigan

    USGS Publications Warehouse

    Woodruff, Laurel G.; Weaver, Thomas L.; Cannon, William F.

    2010-01-01

    This report summarizes results of a study to establish water-quality and geochemical baseline conditions within a small watershed in the Lake Superior region. In 2008, the U.S. Geological Survey (USGS) completed a survey of water-quality parameters and soil and streambed sediment geochemistry of the 83 mi2 Huron River Watershed in the Upper Peninsula of Michigan. Streamflow was measured and water-quality samples collected at a range of flow conditions from six sites on the major tributaries of the Huron River. All water samples were analyzed for a suite of common ions, nutrients, and trace metals. In addition, water samples from each site were analyzed for unfiltered total and methylmercury once during summer low-flow conditions. Soil samples were collected from 31 sites, with up to 4 separate samples collected at each site, delineated by soil horizon. Streambed sediments were collected from 11 sites selected to cover most of the area drained by the Huron River system. USGS data were supplemented with ecological assessments completed in 2006 by the Michigan Department of Environmental Quality using a modified version of their Great Lakes Environmental Assessment Section procedure 51, and again during 2008 using volunteers under supervision of the Michigan Department of Natural Resources. Results from this study define a hydrological, geological, and environmental baseline for the Huron River Watershed prior to any significant mineral exploration or development. Results from the project also serve to refine the design of future regional environmental baseline studies in the Lake Superior Basin.

  8. Agricultural Baseline (BL0) scenario of the 2016 Billion-Ton Report

    DOE Data Explorer

    Davis, Maggie R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)] (ORCID:0000000181319328); Hellwinkel, Chad [University of Tennessee, APAC] (ORCID:0000000173085058); Eaton, Laurence [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)] (ORCID:0000000312709626); Langholtz, Matthew H [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)] (ORCID:0000000281537154); Turhollow, Anthony [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)] (ORCID:0000000228159350); Brandt, Craig [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)] (ORCID:0000000214707379); Myers, Aaron [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)] (ORCID:0000000320373827)

    2016-07-13

    Scientific reason for data generation: to serve as the reference case for the BT16 volume 1 agricultural scenarios. The agricultural baseline runs from 2015 through 2040; a starting year of 2014 is used. Date the data set was last modified: 02/12/2016 How each parameter was produced (methods), format, and relationship to other data in the data set: simulation was developed without offering a farmgate price to energy crops or residues (i.e., building on both the USDA 2015 baseline and the agricultural census data (USDA NASS 2014). Data generated are .txt output files by year, simulation identifier, county code (1-3109). Instruments used: POLYSYS (version POLYS2015_V10_alt_JAN22B) supplied by the University of Tennessee APAC The quality assurance and quality control that have been applied: • Check for negative planted area, harvested area, production, yield and cost values. • Check if harvested area exceeds planted area for annuals. • Check FIPS codes.

  9. A novel type of very long baseline astronomical intensity interferometer

    NASA Astrophysics Data System (ADS)

    Borra, Ermanno F.

    2013-12-01

    This article presents a novel type of very long baseline astronomical interferometer that uses the fluctuations, as a function of time, of the intensity measured by a quadratic detector, which is a common type of astronomical detector. The theory on which the technique is based is validated by laboratory experiments. Its outstanding principal advantages comes from the fact that the angular structure of an astronomical object is simply determined from the visibility of the minima of the spectrum of the intensity fluctuations measured by the detector, as a function of the frequency of the fluctuations, while keeping the spacing between mirrors constant. This would allow a simple setup capable of high angular resolutions because it could use an extremely large baseline. Another major interest is that it allows for a more efficient use of telescope time because observations at a single baseline are sufficient, while amplitude and intensity interferometers need several observations at different baselines. The fact that one does not have to move the telescopes would also allow detecting faster time variations because having to move the telescopes sets a lower limit to the time variations that can be detected. The technique uses wave interaction effects and thus has some characteristics in common with intensity interferometry. A disadvantage of the technique, like in intensity interferometry, is that it needs strong sources if observing at high frequencies (e.g. the visible). This is a minor disadvantage in the radio region. At high frequencies, this disadvantage is mitigated by the fact that, like in intensity interferometry, the requirements of the optical quality of the mirrors used are far less severe than in amplitude interferometry so that poor quality large reflectors (e.g. Cherenkov telescopes) can be used in the optical region.

  10. A Systematic Review and Meta-Analysis of Baseline Ohip-Edent Scores.

    PubMed

    Duale, J M J; Patel, Y A; Wu, J; Hyde, T P

    2018-03-01

    OHIP-EDENT is widely used in the literature to assess Oral-Health-Related-Quality-of-Life (OHRQoL) for edentulous patients. However the normal variance and mean of the baseline OHIP scores has not been reported. It would facilitate critical appraisal of studies if we had knowledge of the normal variation and mean of baseline OHIP-EDENT scores. An established figure for baseline OHIP-EDENT, obtained from a meta-analysis, would simplify comparisons of studies and quantify variations in initial OHRQoL of the trial participants. The aim of this study is to quantify a normal baseline value for pre-operative OHIP-EDENT scores by a systematic review and meta-analysis of the available literature. A systematic literature review was carried. 83 papers were identified that included OHIP-EDENT values. After screening and eligibility assessment, 7 papers were selected and included in the meta-analysis. A meta-analysis for the 7 papers by a random-effect model yielded a mean baseline OHIP-EDENT score of 28.63 with a 95% Confidence intervals from 21.93 to 35.34. A pre-operative baseline OHIP-EDENT has been established by meta-analysis of published papers. This will facilitate the comparison of the initial OHRQoL of one study population to that found elsewhere in the published literature. Copyright© 2018 Dennis Barber Ltd.

  11. Fusion of space-borne multi-baseline and multi-frequency interferometric results based on extended Kalman filter to generate high quality DEMs

    NASA Astrophysics Data System (ADS)

    Zhang, Xiaojie; Zeng, Qiming; Jiao, Jian; Zhang, Jingfa

    2016-01-01

    Repeat-pass Interferometric Synthetic Aperture Radar (InSAR) is a technique that can be used to generate DEMs. But the accuracy of InSAR is greatly limited by geometrical distortions, atmospheric effect, and decorrelations, particularly in mountainous areas, such as western China where no high quality DEM has so far been accomplished. Since each of InSAR DEMs generated using data of different frequencies and baselines has their own advantages and disadvantages, it is therefore very potential to overcome some of the limitations of InSAR by fusing Multi-baseline and Multi-frequency Interferometric Results (MMIRs). This paper proposed a fusion method based on Extended Kalman Filter (EKF), which takes the InSAR-derived DEMs as states in prediction step and the flattened interferograms as observations in control step to generate the final fused DEM. Before the fusion, detection of layover and shadow regions, low-coherence regions and regions with large height error is carried out because MMIRs in these regions are believed to be unreliable and thereafter are excluded. The whole processing flow is tested with TerraSAR-X and Envisat ASAR datasets. Finally, the fused DEM is validated with ASTER GDEM and national standard DEM of China. The results demonstrate that the proposed method is effective even in low coherence areas.

  12. Baseline water quality of Long Meadow Lake, Ponds AP-9 and AP-10, and Black Dog Creek, Hennepin and Dakota counties, Minnesota

    USGS Publications Warehouse

    Payne, G.A.

    1977-01-01

    Long Meadow Lake, Black Dog Creek, and Ponds AP-9 and AP-10 which lie in an area designated for a trunk highway bridge crossing the Minnesota River, were sampled for baseline water quality prior to construction of the bridge. Data collected show that dissolved solids fluctuate seasonally. Dissolved oxygen:/ranged from less than 1 milligram per liter under an ice cover to 13-9 milligrams per liter in the September sample at site 4 in Long Meadow Lake. The phytoplankton analyses showed pulses in algae populations, blue-green algae being the dominant type in at least one sample from each of the water courses.

  13. Centimeter repeatability of the VLBI estimates of European baselines

    NASA Technical Reports Server (NTRS)

    Rius, Antonio; Zarraoa, Nestor; Sardon, Esther; Ma, Chopo

    1992-01-01

    In the last three years, the European Geodetic Very Long Baseline Interferometry (VLBI) Network has grown to a total of six fixed antennas placed in Germany, Italy, Spain and Sweden, all equipped with the standard geodetic VLBI instrumentation and data recording systems. During this period of time, several experiments have been carried out using this interferometer providing data of very high quality due to the excellent sensitivity and performance of the European stations. The purpose of this paper is to study the consistency of the VLBI geodetic results on the European baselines with respect to the different degrees of freedom in the analysis procedure. Used to complete this study were both real and simulated data sets, two different software packages (OCCAM 3.0 and CALC 7.4/SOLVE), and a variety of data analysis strategies.

  14. Baseline Air Quality Assessment of Goods Movement Activities before the Port of Charleston Expansion: A Community–University Collaborative

    PubMed Central

    Wilson, Sacoby M.; Tarver, Siobhan L.; Svendsen, Erik; Jiang, Chengsheng; Ogunsakin, Olalekan A.; Zhang, Hongmei; Campbell, Dayna; Fraser-Rahim, Herbert

    2017-01-01

    Abstract As the demand for goods continues to increase, a collective network of transportation systems is required to facilitate goods movement activities. This study examines air quality near the Port of Charleston before its expansion and briefly describes the establishment and structure of a community–university partnership used to monitor existing pollution. Particulate matter (PM) concentrations (PM2.5 and PM10) were measured using the Thermo Fisher Scientific Partisol 2000i-D Dichotomous Air Sampler, Thermo Scientific Dichotomous Sequential Air Sampler Partisol-Plus 2025-D, and Rupprecht & Patashnick TEOM Series 1400 Sampler at neighborhood (Union Heights, Rosemont, and Accabee) and reference (FAA2.5 and Jenkins Street) sites. Descriptive statistics were performed and an ANOVA (analysis of variance) was calculated to find the difference in overall mean 24-hour PM average concentrations in communities impacted by environmental injustice. PM2.5 (15.2 μg/m3) and PM10 (27.2 μg/m3) maximum concentrations were highest in neighborhoods such as Union Heights neighborhoods due to more goods movement activities. Nevertheless, there was no statistically significant difference in mean concentrations of PM2.5 and PM10 across neighborhood sites. In contrast, mean PM10 neighborhood concentrations were significantly lower than mean PM10 reference concentrations for Union Heights (p = 0.00), Accabee (p ≤ 0.0001), and Rosemont (p = 0.01). Although PM concentrations were lower than current National Ambient Air Quality Standards, this study demonstrated how community–university partners can work collectively to document baseline PM concentrations that will be used to examine changes in air quality after the port expansion brings additional goods movement activities to the area. PMID:29576842

  15. 40 CFR 80.915 - How are the baseline toxics value and baseline toxics volume determined?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false How are the baseline toxics value and... AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Toxics Baseline Determination § 80.915 How are the baseline toxics value and baseline toxics volume determined? (a...

  16. 40 CFR 80.915 - How are the baseline toxics value and baseline toxics volume determined?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 16 2011-07-01 2011-07-01 false How are the baseline toxics value and... AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Toxics Baseline Determination § 80.915 How are the baseline toxics value and baseline toxics volume determined? (a...

  17. Evaluation of feedback interventions for improving the quality assurance of cancer screening in Japan: study design and report of the baseline survey.

    PubMed

    Machii, Ryoko; Saika, Kumiko; Higashi, Takahiro; Aoki, Ayako; Hamashima, Chisato; Saito, Hiroshi

    2012-02-01

    The importance of quality assurance in cancer screening has recently gained increasing attention in Japan. To evaluate and improve quality, checklists and process indicators have been developed. To explore effective methods of enhancing quality in cancer screening, we started a randomized control study of the methods of evaluation and feedback for cancer control from 2009 to 2014. We randomly assigned 1270 municipal governments, equivalent to 71% of all Japanese municipal governments that performed screening programs, into three groups. The high-intensity intervention groups (n = 425) were individually evaluated using both checklist performance and process indicator values, while the low-intensity intervention groups (n= 421) were individually evaluated on the basis of only checklist performance. The control group (n = 424) received only a basic report that included the national average of checklist performance scores. We repeated the survey for each municipality's quality assurance activity performance using checklists and process indicators. In this paper, we report our study design and the result of the baseline survey. The checklist adherence rates were especially low in the checklist elements related to invitation of individuals, detailed monitoring of process indicators such as cancer detection rates according to screening histories and appropriate selection of screening facilities. Screening rate and percentage of examinees who underwent detailed examination tended to be lower for large cities when compared with smaller cities for all cancer sites. The performance of the Japanese cancer screening program in 2009 was identified for the first time.

  18. Characterizing the nature of melt-rock reaction in peridotites from the Santa Elena Ophiolite, NW Costa Rica

    NASA Astrophysics Data System (ADS)

    Carr, D.; Loocke, M. P.; Snow, J. E.; Gazel, E.

    2017-12-01

    The Santa Elena Ophiolite (SEO), located on the northwestern coast of Costa Rica, consists primarily of preserved oceanic mantle and crustal rocks thrust above an accretionary complex. The SEO is predominantly characterized by mantle peridotites (i.e., primarily spinel lherzolite with minor amounts of harzburgite and dunite) cut and intruded by minor pegmatitic gabbros, layered gabbros, plagiogranites, and doleritic and basaltic dykes. Previous studies have concluded that the complex formed in a suprasubduction zone (SSZ) setting based on the geochemical nature of the layered gabbros and plagiogranites (i.e., depleted LREE and HFSE and enriched LILE and Pb), as well, as the peridotites (i.e., low-TiO2, Zr, and V, and high MgO, Cr, and Ni)(Denyer and Gazel, 2009). Eighteen ultramafic samples collected during the winter 2010/2011 field season (SECR11) exhibit abundant evidence for melt-rock reaction (e.g., disseminated plagioclase and plagioclase-spinel, clinopyroxene-spinel, and plagioclase-clinopyroxene symplectites) and provide a unique opportunity to characterize the textural and chemical nature of melt-rock reaction in the SEO. We present the results of a petrologic investigation (i.e., petrography and electron probe microanalysis) of 28 thin sections (19 spinel lherzolites, of which 14 are plagioclase-bearing, 4 pyroxenite veins, and 5 harzburgites) derived from the SECR11 sample set. The results of this investigation have the potential to better our understanding of the nature of melt generation and migration and melt-rock interaction in the SEO mantle section and shed further light on the complex petrogenetic history of the SEO. Denyer, P., Gazel, E., 2009, Journal of South American Earth Sciences, 28:429-442.

  19. Associations of baseline depressed mood and happiness with subsequent well-being in cardiac patients.

    PubMed

    Craner, Julia; Douglas, Kristin Vickers; Dierkhising, Ross; Hathaway, Julie; Goel, Kashish; Thomas, Randal J

    2017-02-01

    The relationship between depressive symptoms and adverse outcomes for patients with cardiac problems has been well established for several decades. However, less is known about other factors that may influence psychosocial outcomes for cardiac patients. To evaluate the association between baseline happiness and depressed mood on later psychosocial functioning among cardiac patients. Participants (N = 250) were patients who had received medical treatment at an academic medical center for a cardiac event. Participants completed questionnaires at two time points: Approximately 2 weeks after they had been discharged from the hospital (baseline) and again 12 weeks later. Participants completed validated measures of depressed mood, happiness, health distress, expectations about health, and quality of life. Baseline depressed mood and happiness both significantly predicted health-related distress and depressive symptoms at follow up. Happiness ratings were associated with lower distress and depressed mood, whereas scores for depressive symptoms showed the opposite pattern. Happiness, but not depressed mood, was a significant predictor of more positive quality of life ratings. Conversely, only depressed mood was a significant predictor of less positive expectations about health. The results of this study suggest that investigating positive baseline affect in addition to depressed mood provides additional useful information that may help explain why some patients have more negative outcomes following cardiac events. Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. Assessing the Influence of Copper-Nickel-Bearing Bedrock on Baseline Water Quality in Filson Creek Watershed, Northeast Minnesota

    NASA Astrophysics Data System (ADS)

    Runkel, R. L.; Jones, P. M.; Elliott, S. M.; Woodruff, L. G.

    2017-12-01

    Mining sulfide-bearing copper (Cu), nickel (Ni), and platinum-group-elements (PGE) deposits in the Duluth Complex of northeast Minnesota could have detrimental effects on surrounding water resources and associated ecosystems. A study was conducted to 1) assess copper, nickel, and other metal concentrations in surface water, bedrock, streambed sediments, and soils in watersheds where the basal part of the Duluth Complex is exposed or near the land surface; and 2) determine if these concentrations, and metal-bearing deposits, are currently influencing regional water quality in areas of potential base-metal mining. One of the watersheds that was assessed was the Filson Creek watershed, where shallow Cu-Ni-PGE deposits are present. Field water-quality, streambed sediments, soils, bedrock, and streamflow data set were collected in Filson Creek and it's watershed in 2014 and 2015. Surface-water samples were analyzed for 12 trace metals (dissolved and total concentrations), 14 inorganic constituents (dissolved concentrations), alkalinity, 18 O /16O and 2H/1H isotopes, and total and dissolved organic carbon. Background total Cu and Ni concentrations in the creek in 2014 and 2015 ranged from 1.2 to 10.8 micrograms per liter (µg/L), and 1.7 to 8.4 µg/L, respectively. The concentrations of copper, nickel, and other trace metals in surface waters and streambed sediments reflects the geochemistry of underlying rock types and glacially transported unconsolidated material, establishing baseline conditions prior to any mining. Dissolved and total organic carbon (DOC and TOC) concentrations in surface waters are very high compared to most surface waters in Minnesota, ranging from 21.3 to 43.2 milligrams per liter (mg/L), and 22.4 and 53.5 mg/L. Synoptic water-quality and flow data from a tracer test conducted over a stream segment of Filson Creek above a shallow Cu-Ni-PGE deposit (Spruce Road Deposit) was used with the 2014-15 water-quality and synthetic flow data to calibrate

  1. Questa baseline and pre-mining ground-water-quality investigation. 16. Quality assurance and quality control for water analyses

    USGS Publications Warehouse

    McCleskey, R. Blaine; Nordstrom, D. Kirk; Naus, Cheryl A.

    2004-01-01

    The Questa baseline and pre-mining ground-water quality investigation has the main objective of inferring the ground-water chemistry at an active mine site. Hence, existing ground-water chemistry and its quality assurance and quality control is of crucial importance to this study and a substantial effort was spent on this activity. Analyses of seventy-two blanks demonstrated that contamination from processing, handling, and analyses were minimal. Blanks collected using water deionized with anion and cation exchange resins contained elevated concentrations of boron (0.17 milligrams per liter (mg/L)) and silica (3.90 mg/L), whereas double-distilled water did not. Boron and silica were not completely retained by the resins because they can exist as uncharged species in water. Chloride was detected in ten blanks, the highest being 3.9 mg/L, probably as the result of washing bottles, filter apparatuses, and tubing with hydrochloric acid. Sulfate was detected in seven blanks; the highest value was 3.0 mg/L, most likely because of carryover from the high sulfate waters sampled. With only a few exceptions, the remaining blank analyses were near or below method detection limits. Analyses of standard reference water samples by cold-vapor atomic fluorescence spectrometry, ion chromatography, inductively coupled plasma-optical emission spectrometry, inductively coupled plasma-mass spectrometry, FerroZine, graphite furnace atomic absorption spectrometry, hydride generation atomic spectrometry, and titration provided an accuracy check. For constituents greater than 10 times the detection limit, 95 percent of the samples had a percent error of less than 8.5. For constituents within 10 percent of the detection limit, the percent error often increased as a result of measurement imprecision. Charge imbalance was calculated using WATEQ4F and 251 out of 257 samples had a charge imbalance less than 11.8 percent. The charge imbalance for all samples ranged from -16 to 16 percent. Spike

  2. Schema therapy for personality disorders in older adults: a multiple-baseline study.

    PubMed

    Videler, Arjan C; van Alphen, Sebastiaan P J; van Royen, Rita J J; van der Feltz-Cornelis, Christina M; Rossi, Gina; Arntz, Arnoud

    2018-06-01

    No studies have been conducted yet into the effectiveness of treatment of personality disorders in later life. This study is a first test of the effectiveness of schema therapy for personality disorders in older adults. Multiple-baseline design with eight cluster C personality disorder patients, with a mean age of   69. After a baseline phase with random length, schema therapy was given during the first year, followed by follow-up sessions during six months. Participants weekly rated the credibility of dysfunctional core beliefs. Symptomatic distress, early maladaptive schemas, quality of life and target complaints were assessed every six months and personality disorder diagnosis was assessed before baseline and after follow-up. Data were analyzed with mixed regression analyses. Results revealed significant linear trends during treatment phases, but not during baseline and follow-up. The scores during follow-up remained stable and were significantly lower compared to baseline, with high effect sizes. Seven participants remitted from their personality disorder diagnosis. Schema therapy appears an effective treatment for cluster C personality disorders in older adults. This finding is highly innovative as this is the first study exploring the effectiveness of psychotherapy, in this case schema therapy, for personality disorders in older adults.

  3. Baseline assessment of instream and riparian-zone biological resources on the Rio Grande in and near Big Bend National Park, Texas

    USGS Publications Warehouse

    Moring, James Bruce

    2002-01-01

    Five study sites, and a sampling reach within each site, were established on the Rio Grande in and near Big Bend National Park in 1999 to provide the National Park Service with data and information on the status of stream habitat, fish communities, and benthic macroinvertebrates. Differences in stream-habitat conditions and riparian vegetation reflect differences in surface geology among the five sampling reaches. In the most upstream reach, Colorado Canyon, where igneous rock predominates, streambed material is larger; and riparian vegetation is less diverse and not as dense as in the four other, mostly limestone reaches. Eighteen species of fish and a total of 474 individuals were collected among the five reaches; 348 of the 474 were minnows. The most fish species (15) were collected at the Santa Elena reach and the fewest species (9) at the Colorado Canyon and Johnson Ranch reaches. The fish community at Colorado Canyon was least like the fish communities at the four other reaches. Fish trophic structure reflected fish-community structure among the five reaches. Invertivores made up at least 60 percent of the trophic structure at all reaches except Colorado Canyon. Piscivores dominated the trophic structure at Colorado Canyon. At the four other reaches, piscivores were the smallest trophic group. Eighty percent of the benthic macroinvertebrate taxa collected were aquatic insects. Two species of blackfly were the most frequently collected invertebrate taxon. Net-spinning caddisflies were common at all reaches except Santa Elena. The aquatic-insect community at the Boquillas reach was least similar to the aquatic-insect community at the other reaches.

  4. The hELENa project - I. Stellar populations of early-type galaxies linked with local environment and galaxy mass

    NASA Astrophysics Data System (ADS)

    Sybilska, A.; Lisker, T.; Kuntschner, H.; Vazdekis, A.; van de Ven, G.; Peletier, R.; Falcón-Barroso, J.; Vijayaraghavan, R.; Janz, J.

    2017-09-01

    We present the first in a series of papers in The role of Environment in shaping Low-mass Early-type Nearby galaxies (hELENa) project. In this paper, we combine our sample of 20 low-mass early types (dEs) with 258 massive early types (ETGs) from the ATLAS3D survey - all observed with the SAURON integral field unit - to investigate early-type galaxies' stellar population scaling relations and the dependence of the population properties on local environment, extended to the low-σ regime of dEs. The ages in our sample show more scatter at lower σ values, indicative of less massive galaxies being affected by the environment to a higher degree. The shape of the age-σ relations for cluster versus non-cluster galaxies suggests that cluster environment speeds up the placing of galaxies on the red sequence. While the scaling relations are tighter for cluster than for the field/group objects, we find no evidence for a difference in average population characteristics of the two samples. We investigate the properties of our sample in the Virgo cluster as a function of number density (rather than simple clustrocentric distance) and find that dE ages correlate with the local density such that galaxies in regions of lower density are younger, likely because they are later arrivals to the cluster or have experienced less pre-processing in groups, and consequently used up their gas reservoir more recently. Overall, dE properties correlate more strongly with density than those of massive ETGs, which was expected as less massive galaxies are more susceptible to external influences.

  5. Subjective Sleep Quality Deteriorates Prior to Development of Painful Temporomandibular Disorder

    PubMed Central

    Sanders, Anne E.; Akinkugbe, Aderonke A.; Bair, Eric; Fillingim, Roger B.; Greenspan, Joel D.; Ohrbach, Richard; Dubner, Ronald; Maixner, William; Slade, Gary D.

    2016-01-01

    There is good evidence that poor sleep quality increases risk of painful temporomandibular disorder (TMD). However little is known about the course of sleep quality in the months preceding TMD onset, and whether the relationship is mediated by heightened sensitivity to pain. The Pittsburgh Sleep Quality Index was administered at enrollment into the OPPERA prospective cohort study. Thereafter the Sleep Quality Numeric Rating Scale was administered every three months to 2,453 participants. Sensitivity to experimental pressure pain and pinprick pain stimuli was measured at baseline and repeated during follow-up of incident TMD cases (n=220) and matched TMD-free controls (n=193). Subjective sleep quality deteriorated progressively, but only in those who subsequently developed TMD. A Cox proportional hazards model showed that risk of TMD was greater among participants whose sleep quality worsened during follow-up (adjusted hazard ratio=1.73, 95% confidence limits: 1.29, 2.32). This association was independent of baseline measures of sleep quality, psychological stress, somatic awareness, comorbid conditions, non-pain facial symptoms and demographics. Poor baseline sleep quality was not significantly associated with baseline pain sensitivity or with subsequent change in pain sensitivity. Furthermore the relationship between sleep quality and TMD incidence was not mediated via baseline pain sensitivity nor change in pain sensitivity. PMID:26902644

  6. Baseline models of trace elements in major aquifers of the United States

    USGS Publications Warehouse

    Lee, L.; Helsel, D.

    2005-01-01

    Trace-element concentrations in baseline samples from a survey of aquifers used as potable-water supplies in the United States are summarized using methods appropriate for data with multiple detection limits. The resulting statistical distribution models are used to develop summary statistics and estimate probabilities of exceeding water-quality standards. The models are based on data from the major aquifer studies of the USGS National Water Quality Assessment (NAWQA) Program. These data were produced with a nationally-consistent sampling and analytical framework specifically designed to determine the quality of the most important potable groundwater resources during the years 1991-2001. The analytical data for all elements surveyed contain values that were below several detection limits. Such datasets are referred to as multiply-censored data. To address this issue, a robust semi-parametric statistical method called regression on order statistics (ROS) is employed. Utilizing the 90th-95th percentile as an arbitrary range for the upper limits of expected baseline concentrations, the models show that baseline concentrations of dissolved Ba and Zn are below 500 ??g/L. For the same percentile range, dissolved As, Cu and Mo concentrations are below 10 ??g/L, and dissolved Ag, Be, Cd, Co, Cr, Ni, Pb, Sb and Se are below 1-5 ??g/L. These models are also used to determine the probabilities that potable ground waters exceed drinking water standards. For dissolved Ba, Cr, Cu, Pb, Ni, Mo and Se, the likelihood of exceeding the US Environmental Protection Agency standards at the well-head is less than 1-1.5%. A notable exception is As, which has approximately a 7% chance of exceeding the maximum contaminant level (10 ??g/L) at the well head.

  7. [The intervention of Dr Francisco Díaz in the inquisitorial process against Elena/o de Cespedes, a transsexual surgeon found guilty by the Inquistion in Toledo in 1587].

    PubMed

    Maganto Pavón, Emilio

    2007-10-01

    To make known, comprehensively, an almost unknown episode in the life of Dr. Francisco Diaz (1527-1590), surgeon of the king Philip II, and author of the first urology treaty in the history of medicine. To our knowledge, to date there were few references about the participation that, as an expert, Francisco Diaz had to have in the inquisitorial process against Elena de Cespedes, a presumed hermaphrodite accused by the Inquisition because being a woman married another one pretending to be a man. The trial was carried out in Toledo in 1587 and had great impact in that time, because the accused, dressing with male clothes and usurping the prerogatives of a man, had gotten by fraud titles and favours which were forbidden for women, the title of surgeon among them. Except for the reference by Folch Jou and Burshatin, both short and incomplete, no other author or biographer of the famous surgeon had cited this episode of his life, which to our judgment could mean a great damage to his reputation. We reviewed the works by the two aforementioned authors, all the works and biographies about Dr. Francisco Diaz that we could found, and microfilmed and transcript the whole bundle 234, expedient 24, from the section Inquisition at the National Historical Archive in Madrid, corresponding to Elena de Cespedes (alias Eleno) (> 500 pages) to obtain the greatest amount of data about the accused and the performance of Dr. Francisco Diaz. Francisco Diaz was requested, as an expert, by the Vicar of Madrid to perform the examination of the genitourinary organs to give or not marriage license to that woman saying she was a man. In his report in the year 1586, surprisingly the urologist declared that the petitioner was a man. As it would be demonstrated during the trial, the accused, who alleged being hermaphrodite in her defense, had been able to deceive the expert with her tricks altering her genital morphology. Thanks to her surgical knowledge she had mutilated herself surgically

  8. Lubrication System Failure Baseline Testing on an Aerospace Quality Gear Mesh

    NASA Technical Reports Server (NTRS)

    Handschuh, Robert F.; Morales, Wilfredo

    2000-01-01

    Aerospace drive systems are required to survive a loss-of-lubrication test for qualification. In many cases emergency lubrication systems need to be designed and utilized to permit the drive system to pass this difficult requirement. The weight of emergency systems can adversely affect the mission capabilities of the aircraft. The possibility to reduce the emergency system weight through the use of mist lubrication will be described. Mist lubrication involves the delivery of a minute amount of an organic liquid as a vapor or fine mist in flowing compressed air to rubbing surfaces. At the rubbing surface, the vapor or mist reacts to form a solid lubricating film. The aim of this study was to establish a baseline for gear behavior under oil depleted conditions. A reactive vapor-mist lubrication method is described and proposed as a candidate emergency lubrication system.

  9. TAPIR--Finnish national geochemical baseline database.

    PubMed

    Jarva, Jaana; Tarvainen, Timo; Reinikainen, Jussi; Eklund, Mikael

    2010-09-15

    In Finland, a Government Decree on the Assessment of Soil Contamination and Remediation Needs has generated a need for reliable and readily accessible data on geochemical baseline concentrations in Finnish soils. According to the Decree, baseline concentrations, referring both to the natural geological background concentrations and the diffuse anthropogenic input of substances, shall be taken into account in the soil contamination assessment process. This baseline information is provided in a national geochemical baseline database, TAPIR, that is publicly available via the Internet. Geochemical provinces with elevated baseline concentrations were delineated to provide regional geochemical baseline values. The nationwide geochemical datasets were used to divide Finland into geochemical provinces. Several metals (Co, Cr, Cu, Ni, V, and Zn) showed anomalous concentrations in seven regions that were defined as metal provinces. Arsenic did not follow a similar distribution to any other elements, and four arsenic provinces were separately determined. Nationwide geochemical datasets were not available for some other important elements such as Cd and Pb. Although these elements are included in the TAPIR system, their distribution does not necessarily follow the ones pre-defined for metal and arsenic provinces. Regional geochemical baseline values, presented as upper limit of geochemical variation within the region, can be used as trigger values to assess potential soil contamination. Baseline values have also been used to determine upper and lower guideline values that must be taken into account as a tool in basic risk assessment. If regional geochemical baseline values are available, the national guideline values prescribed in the Decree based on ecological risks can be modified accordingly. The national geochemical baseline database provides scientifically sound, easily accessible and generally accepted information on the baseline values, and it can be used in various

  10. Variables associated with sleep quality in chronic tension-type headache: A cross-sectional and longitudinal design.

    PubMed

    Benito-González, Elena; Palacios-Ceña, Maria; Fernández-Muñoz, Juan J; Castaldo, Matteo; Wang, Kelun; Catena, Antonella; Arendt-Nielsen, Lars; Fernández-de-Las-Peñas, César

    2018-01-01

    To investigate variables associated at baseline (cross-sectional design) and at one year (longitudinal design) with the quality of sleep in chronic tension-type headache (CTTH). One hundred and eighty (n = 180) and 135 individuals with CTTH participated in the cross-sectional and longitudinal design respectively. Clinical features were collected with a 4-weeks headache diary at baseline and one-year follow-up. Sleep quality was assessed at baseline and 1-year follow-up with the Pittsburgh Sleep Quality Index. Anxiety and depression (Hospital Anxiety and Depression Scale-HADS), burden of headache (Headache Disability Inventory-HDI), quality of life (SF-36 questionnaire), and pressure pain thresholds (PPTs) at trigeminal, extra-trigeminal and widespread area were assessed at baseline. Hierarchical regression analyses were conducted to determine the associations between variables at baseline and 1-year follow-up with sleep quality. At baseline positive correlations between sleep quality and headache intensity, headache frequency, headache duration, emotional and physical burden of headache and depression were observed. The regression analyses found that depression and emotional burden of headache explained 27.5% of the variance in sleep quality at baseline (r2 = .262; F = 23.72 P < .001). At one-year, sleep quality was significantly associated with baseline burden of headache, depression, widespread PPTs, vitality and mental health domains. Regression analyses revealed that vitality, PPT over the second metacarpal and PPT over the neck explained 30.0% of the variance of sleep quality at one-year (r2 = .269, F = 9.71, P < .001). It seems that sleep quality exhibits a complex interaction in individuals with CTTH since depression and the emotional burden were associated with sleep quality at baseline, but vitality and PPTs over extra-trigeminal areas were associated with the quality of sleep at one-year.

  11. Layover and shadow detection based on distributed spaceborne single-baseline InSAR

    NASA Astrophysics Data System (ADS)

    Huanxin, Zou; Bin, Cai; Changzhou, Fan; Yun, Ren

    2014-03-01

    Distributed spaceborne single-baseline InSAR is an effective technique to get high quality Digital Elevation Model. Layover and Shadow are ubiquitous phenomenon in SAR images because of geometric relation of SAR imaging. In the signal processing of single-baseline InSAR, the phase singularity of Layover and Shadow leads to the phase difficult to filtering and unwrapping. This paper analyzed the geometric and signal model of the Layover and Shadow fields. Based on the interferometric signal autocorrelation matrix, the paper proposed the signal number estimation method based on information theoretic criteria, to distinguish Layover and Shadow from normal InSAR fields. The effectiveness and practicability of the method proposed in the paper are validated in the simulation experiments and theoretical analysis.

  12. Comparison of fluorescence rejection methods of baseline correction and shifted excitation Raman difference spectroscopy

    NASA Astrophysics Data System (ADS)

    Cai, Zhijian; Zou, Wenlong; Wu, Jianhong

    2017-10-01

    Raman spectroscopy has been extensively used in biochemical tests, explosive detection, food additive and environmental pollutants. However, fluorescence disturbance brings a big trouble to the applications of portable Raman spectrometer. Currently, baseline correction and shifted-excitation Raman difference spectroscopy (SERDS) methods are the most prevailing fluorescence suppressing methods. In this paper, we compared the performances of baseline correction and SERDS methods, experimentally and simulatively. Through the comparison, it demonstrates that the baseline correction can get acceptable fluorescence-removed Raman spectrum if the original Raman signal has good signal-to-noise ratio, but it cannot recover the small Raman signals out of large noise background. By using SERDS method, the Raman signals, even very weak compared to fluorescence intensity and noise level, can be clearly extracted, and the fluorescence background can be completely rejected. The Raman spectrum recovered by SERDS has good signal to noise ratio. It's proved that baseline correction is more suitable for large bench-top Raman system with better quality or signal-to-noise ratio, while the SERDS method is more suitable for noisy devices, especially the portable Raman spectrometers.

  13. PENNSYLVANIA BASELINE

    EPA Science Inventory

    This report was prepared as part of the Ohio River Basin Energy Study (ORBES), a multidisciplinary policy research program supported by the Environmental Protection Agency. Its purpose is to provide baseline information on Pennsylvania, one of the six states included partly or to...

  14. Baseline measure of health-related quality of life (Functional Assessment of Cancer Therapy-Esophagus) is associated with overall survival in patients with esophageal cancer.

    PubMed

    Kidane, Biniam; Sulman, Joanne; Xu, Wei; Kong, Qin Quinn; Wong, Rebecca; Knox, Jennifer J; Darling, Gail E

    2016-06-01

    Functional Assessment of Cancer Therapy-Esophagus is a health-related quality of life instrument validated in patients with esophageal cancer. It is composed of a general component and an esophageal cancer subscale. Our objective was to determine whether the baseline Functional Assessment of Cancer Therapy-Esophagus and esophageal cancer subscale scores are associated with survival in patients with stage II and III cancer of the gastroesophageal junction or thoracic esophagus. Data from 4 prospective studies in Canadian academic hospitals were combined. These included consecutive patients with stage II and III esophageal cancer who received neoadjuvant therapy followed by surgery or chemoradiation/radiation alone. All patients completed baseline Functional Assessment of Cancer Therapy-Esophagus. Functional Assessment of Cancer Therapy-Esophagus and esophageal cancer subscale scores were dichotomized on the basis of median scores. Cox regression analyses were performed. There were 207 patients treated between 1996 and 2014. Mean age was 61 ± 10.6 years. Approximately 69.6% of patients (n = 144) had adenocarcinoma. All patients had more than 9 months of follow-up. In patients with stage II and III, 93 deaths were observed. When treated as continuous variables, baseline Functional Assessment of Cancer Therapy-Esophagus and esophageal cancer subscale were associated with survival with hazard ratios of 0.89 (95% confidence interval [CI], 0.81-0.96; P = .005) and 0.68 (95% CI, 0.56-0.82; P < .001), respectively. When dichotomized, they were also associated with survival with a hazard ratio of 0.58 (95% CI, 0.38-0.89; P = .01) and 0.43 (95% CI, 0.28-0.67; P < .001), respectively. In patients with stage II and III esophageal cancer being considered for therapy, higher baseline Functional Assessment of Cancer Therapy-Esophagus and esophageal cancer subscale were independently associated with longer survival, even after adjusting for age, stage, histology, and

  15. Oscillation Baselining and Analysis Tool

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    PNNL developed a new tool for oscillation analysis and baselining. This tool has been developed under a new DOE Grid Modernization Laboratory Consortium (GMLC) Project (GM0072 - “Suite of open-source applications and models for advanced synchrophasor analysis”) and it is based on the open platform for PMU analysis. The Oscillation Baselining and Analysis Tool (OBAT) performs the oscillation analysis and identifies modes of oscillations (frequency, damping, energy, and shape). The tool also does oscillation event baselining (fining correlation between oscillations characteristics and system operating conditions).

  16. Nonlinear Dynamic Inversion Baseline Control Law: Architecture and Performance Predictions

    NASA Technical Reports Server (NTRS)

    Miller, Christopher J.

    2011-01-01

    A model reference dynamic inversion control law has been developed to provide a baseline control law for research into adaptive elements and other advanced flight control law components. This controller has been implemented and tested in a hardware-in-the-loop simulation; the simulation results show excellent handling qualities throughout the limited flight envelope. A simple angular momentum formulation was chosen because it can be included in the stability proofs for many basic adaptive theories, such as model reference adaptive control. Many design choices and implementation details reflect the requirements placed on the system by the nonlinear flight environment and the desire to keep the system as basic as possible to simplify the addition of the adaptive elements. Those design choices are explained, along with their predicted impact on the handling qualities.

  17. CryoSat Level1b SAR/SARin BaselineC: Product Format and Algorithm Improvements

    NASA Astrophysics Data System (ADS)

    Scagliola, Michele; Fornari, Marco; Di Giacinto, Andrea; Bouffard, Jerome; Féménias, Pierre; Parrinello, Tommaso

    2015-04-01

    CryoSat was launched on the 8th April 2010 and is the first European ice mission dedicated to the monitoring of precise changes in the thickness of polar ice sheets and floating sea ice. Cryosat carries an innovative radar altimeter called the Synthetic Aperture Interferometric Altimeter (SIRAL), that transmits pulses at a high pulse repetition frequency thus making the received echoes phase coherent and suitable for azimuth processing. This allows to reach a significantly improved along track resolution with respect to traditional pulse-width limited altimeters. CryoSat is the first altimetry mission operating in SAR mode and continuous improvements in the Level1 Instrument Processing Facility (IPF1) are being identified, tested and validated in order to improve the quality of the Level1b products. The current IPF, Baseline B, was released in operation in February 2012. A reprocessing campaign followed, in order to reprocess the data since July 2010. After more than 2 years of development, the release in operations of Baseline C is expected in the first half of 2015. BaselineC Level1b products will be distributed in an updated format, including for example the attitude information (roll, pitch and yaw) and, for SAR/SARIN, the waveform length doubled with respect to Baseline B. Moreveor, various algorithm improvements have been identified: • a datation bias of about -0.5195 ms will be corrected (SAR/SARIn) • a range bias of about 0.6730 m will be corrected (SAR/SARIn) • a roll bias of 0.1062 deg and a pitch bias of 0.0520 deg • Surface sample stack weighting to filter out the single look echoes acquired at highest look angle, that results in a sharpening of the 20Hz waveforms With the operational release of BaselineC, the second CryoSat reprocessing campaign will be initiated, taking benefit of the upgrade implemented in the IPF1 processing chain but also at IPF2 level. The reprocessing campaign will cover the full Cryosat mission starting on 16th July 2010

  18. Assessment of local GNSS baselines at co-location sites

    NASA Astrophysics Data System (ADS)

    Herrera Pinzón, Iván; Rothacher, Markus

    2018-01-01

    As one of the major contributors to the realisation of the International Terrestrial Reference System (ITRS), the Global Navigation Satellite Systems (GNSS) are prone to suffer from irregularities and discontinuities in time series. While often associated with hardware/software changes and the influence of the local environment, these discrepancies constitute a major threat for ITRS realisations. Co-located GNSS at fundamental sites, with two or more available instruments, provide the opportunity to mitigate their influence while improving the accuracy of estimated positions by examining data breaks, local biases, deformations, time-dependent variations and the comparison of GNSS baselines with existing local tie measurements. With the use of co-located GNSS data from a subset sites of the International GNSS Service network, this paper discusses a global multi-year analysis with the aim of delivering homogeneous time series of coordinates to analyse system-specific error sources in the local baselines. Results based on the comparison of different GNSS-based solutions with the local survey ties show discrepancies of up to 10 mm despite GNSS coordinate repeatabilities at the sub-mm level. The discrepancies are especially large for the solutions using the ionosphere-free linear combination and estimating tropospheric zenith delays, thus corresponding to the processing strategy used for global solutions. Snow on the antennas causes further problems and seasonal variations of the station coordinates. These demonstrate the need for a permanent high-quality monitoring of the effects present in the short GNSS baselines at fundamental sites.

  19. Making Quality Health Websites a National Public Health Priority: Toward Quality Standards.

    PubMed

    Devine, Theresa; Broderick, Jordan; Harris, Linda M; Wu, Huijuan; Hilfiker, Sandra Williams

    2016-08-02

    Most US adults have limited health literacy skills. They struggle to understand complex health information and services and to make informed health decisions. The Internet has quickly become one of the most popular places for people to search for information about their health, thereby making access to quality information on the Web a priority. However, there are no standardized criteria for evaluating Web-based health information. Every 10 years, the US Department of Health and Human Services' Office of Disease Prevention and Health Promotion (ODPHP) develops a set of measurable objectives for improving the health of the nation over the coming decade, known as Healthy People. There are two objectives in Healthy People 2020 related to website quality. The first is objective Health Communication and Health Information Technology (HC/HIT) 8.1: increase the proportion of health-related websites that meet 3 or more evaluation criteria for disclosing information that can be used to assess information reliability. The second is objective HC/HIT-8.2: increase the proportion of health-related websites that follow established usability principles. The ODPHP conducted a nationwide assessment of the quality of Web-based health information using the Healthy People 2020 objectives. The ODPHP aimed to establish (1) a standardized approach to defining and measuring the quality of health websites; (2) benchmarks for measurement; (3) baseline data points to capture the current status of website quality; and (4) targets to drive improvement. The ODPHP developed the National Quality Health Website Survey instrument to assess the quality of health-related websites. The ODPHP used this survey to review 100 top-ranked health-related websites in order to set baseline data points for these two objectives. The ODPHP then set targets to drive improvement by 2020. This study reviewed 100 health-related websites. For objective HC/HIT-8.1, a total of 58 out of 100 (58.0%) websites met 3 or

  20. GPS-Based Precision Baseline Reconstruction for the TanDEM-X SAR-Formation

    NASA Technical Reports Server (NTRS)

    Montenbruck, O.; vanBarneveld, P. W. L.; Yoon, Y.; Visser, P. N. A. M.

    2007-01-01

    The TanDEM-X formation employs two separate spacecraft to collect interferometric Synthetic Aperture Radar (SAR) measurements over baselines of about 1 km. These will allow the generation ofa global Digital Elevation Model (DEM) with an relative vertical accuracy of 2-4 m and a 10 m ground resolution. As part of the ground processing, the separation of the SAR antennas at the time of each data take must be reconstructed with a 1 mm accuracy using measurements from two geodetic grade GPS receivers. The paper discusses the TanDEM-X mission as well as the methods employed for determining the interferometric baseline with utmost precision. Measurements collected during the close fly-by of the two GRACE satellites serve as a reference case to illustrate the processing concept, expected accuracy and quality control strategies.

  1. Post-traumatic stress symptom development as a function of changing witnessing in-home violence and changing peer relationship quality: Evaluating protective effects of peer relationship quality.

    PubMed

    Mishra, Aura A; Christ, Sharon L; Schwab-Reese, Laura M; Nair, Nayantara

    2018-07-01

    In the present study, witnessing in-home violence and peer relationship quality are evaluated as to their relative impact on Post Traumatic Stress (PTS) symptoms among children aged 8 to 17 investigated by child protective services (CPS) for maltreatment exposure. The sample included 2151 children from the National Survey of Child and Adolescent Well-Being II (NSCAW II). Linear growth models were estimated to assess associations between changes in PTS symptoms, witnessing in-home violence, and peer relationship quality over time. Greater frequency of witnessing in-home violence at baseline (i.e. wave 1) was associated with higher baseline PTS symptoms (β = 0.44). Increases in witnessing in-home violence frequency over time (average annual change across three years) had a strong association with increases in PTS symptoms over time (β = 0.88). Baseline peer relationship quality was associated with fewer PTS symptoms at baseline (β = -0.45). Increases in peer relationship quality over time were strongly associated with declines in PTS symptoms over time (β = -0.68). Peer relationship quality at baseline did not moderate baseline or over time associations between witnessing in-home violence and PTS symptoms. The average decline in PTS symptoms due to decreases in witnessing in-home violence and increases in peer relationship quality was 0.51 and 0.65 standard deviations respectively, over the three-year study period. Reducing chronic witnessing in-home violence and promoting the development of healthy social relationships with peers are critical for PTS symptom recovery. Copyright © 2018 Elsevier Ltd. All rights reserved.

  2. The effect of erythropoietin on cognition in affective disorders - Associations with baseline deficits and change in subjective cognitive complaints.

    PubMed

    Ott, Caroline Vintergaard; Vinberg, Maj; Kessing, Lars V; Miskowiak, Kamilla W

    2016-08-01

    This is a secondary data analysis from our erythropoietin (EPO) trials. We examine (I) whether EPO improves speed of complex cognitive processing across bipolar and unipolar disorder, (II) if objective and subjective baseline cognitive impairment increases patients׳ chances of treatment-efficacy and (III) if cognitive improvement correlates with better subjective cognitive function, quality of life and socio-occupational capacity. Patients with unipolar or bipolar disorder were randomized to eight weekly EPO (N=40) or saline (N=39) infusions. Cognition, mood, quality of life and socio-occupational capacity were assessed at baseline (week 1), after treatment completion (week 9) and at follow-up (week 14). We used repeated measures analysis of covariance to investigate the effect of EPO on speed of complex cognitive processing. With logistic regression, we examined whether baseline cognitive impairment predicted treatment-efficacy. Pearson correlations were used to assess associations between objective and subjective cognition, quality of life and socio-occupational capacity. EPO improved speed of complex cognitive processing across affective disorders at weeks 9 and 14 (p≤0.05). In EPO-treated patients, baseline cognitive impairment increased the odds of treatment-efficacy on cognition at weeks 9 and 14 by a factor 9.7 (95% CI:1.2-81.1) and 9.9 (95% CI:1.1-88.4), respectively (p≤0.04). Subjective cognitive complaints did not affect chances of treatment-efficacy (p≥0.45). EPO-associated cognitive improvement correlated with reduced cognitive complaints but not with quality of life or socio-occupational function. As the analyses were performed post-hoc, findings are only hypothesis-generating. In conclusion, pro-cognitive effects of EPO occurred across affective disorders. Neuropsychological screening for cognitive dysfunction may be warranted in future cognition trials. Copyright © 2016 Elsevier B.V. and ECNP. All rights reserved.

  3. Filter design for cancellation of baseline-fluctuation in needle EMG recordings.

    PubMed

    Rodríguez-Carreño, I; Malanda-Trigueros, A; Gila-Useros, L; Navallas-Irujo, J; Rodríguez-Falces, J

    2006-01-01

    Appropriate cancellation of the baseline fluctuation (BLF) is an important issue when recording EMG signals as it may degrade signal quality and distort qualitative and quantitative analysis. We present a novel filter-design approach for automatic cancellation of the BLF based on several signal processing techniques used sequentially. The methodology is to estimate the spectral content of the BLF, and then to use this estimation to design a high-pass FIR filter that cancel the BLF present in the signal. Two merit figures are devised for measuring the degree of BLF present in an EMG record. These figures are used to compare our method with the conventional approach, which naively considers the baseline course to be of constant (without any fluctuation) potential shift. Applications of the technique on real and simulated EMG signals show the superior performance of our approach in terms of both visual inspection and the merit figures.

  4. COMSATCOM service technical baseline strategy development approach using PPBW concept

    NASA Astrophysics Data System (ADS)

    Nguyen, Tien M.; Guillen, Andy T.

    2016-05-01

    This paper presents an innovative approach to develop a Commercial Satellite Communications (COMSATCOM) service Technical Baseline (TB) and associated Program Baseline (PB) strategy using Portable Pool Bandwidth (PPBW) concept. The concept involves trading of the purchased commercial transponders' Bandwidths (BWs) with existing commercial satellites' bandwidths participated in a "designated pool bandwidth"3 according to agreed terms and conditions. Space Missile Systems Center (SMC) has been implementing the Better Buying Power (BBP 3.0) directive4 and recommending the System Program Offices (SPO) to own the Program and Technical Baseline (PTB) [1, 2] for the development of flexible acquisition strategy and achieving affordability and increased in competition. This paper defines and describes the critical PTB parameters and associated requirements that are important to the government SPO for "owning" an affordable COMSATCOM services contract using PPBW trading concept. The paper describes a step-by-step approach to optimally perform the PPBW trading to meet DoD and its stakeholders (i) affordability requirement, and (ii) fixed and variable bandwidth requirements by optimizing communications performance, cost and PPBW accessibility in terms of Quality of Services (QoS), Bandwidth Sharing Ratio (BSR), Committed Information Rate (CIR), Burstable Information Rate (BIR), Transponder equivalent bandwidth (TPE) and transponder Net Presence Value (NPV). The affordable optimal solution that meets variable bandwidth requirements will consider the operating and trading terms and conditions described in the Fair Access Policy (FAP).

  5. Establishing a store baseline during interim storage of waste packages and a review of potential technologies for base-lining

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McTeer, Jennifer; Morris, Jenny; Wickham, Stephen

    Interim storage is an essential component of the waste management lifecycle, providing a safe, secure environment for waste packages awaiting final disposal. In order to be able to monitor and detect change or degradation of the waste packages, storage building or equipment, it is necessary to know the original condition of these components (the 'waste storage system'). This paper presents an approach to establishing the baseline for a waste-storage system, and provides guidance on the selection and implementation of potential base-lining technologies. The approach is made up of two sections; assessment of base-lining needs and definition of base-lining approach. Duringmore » the assessment of base-lining needs a review of available monitoring data and store/package records should be undertaken (if the store is operational). Evolutionary processes (affecting safety functions), and their corresponding indicators, that can be measured to provide a baseline for the waste-storage system should then be identified in order for the most suitable indicators to be selected for base-lining. In defining the approach, identification of opportunities to collect data and constraints is undertaken before selecting the techniques for base-lining and developing a base-lining plan. Base-lining data may be used to establish that the state of the packages is consistent with the waste acceptance criteria for the storage facility and to support the interpretation of monitoring and inspection data collected during store operations. Opportunities and constraints are identified for different store and package types. Technologies that could potentially be used to measure baseline indicators are also reviewed. (authors)« less

  6. Do patients with brain metastases selected for whole brain radiotherapy have worse baseline quality of life as compared to those for radiosurgery or neurosurgery (with or without whole brain radiotherapy)?

    PubMed

    Chow, Ronald; Tsao, May; Pulenzas, Natalie; Zhang, Liying; Sahgal, Arjun; Cella, David; Soliman, Hany; Danjoux, Cyril; DeAngelis, Carlo; Vuong, Sherlyn; Chow, Edward

    2016-01-01

    The purpose was to examine the baseline characteristics, symptoms and quality of life (QOL) in patients who receive different treatments for brain metastases. Eligible patients were divided and analysed based on their treatment: whole brain radiotherapy (WBRT) alone versus stereotactic radiosurgery (SRS) or neurosurgery with or without WBRT. The Functional Assessment of Cancer Therapy-Brain (FACT-Br) items were grouped according to different domains for summary scores. The domains used for summary scores were physical, social/family, emotional, functional well-being (FWB) and additional concerns. A total of 120 patients were enrolled, with 37 treated with WBRT alone and 83 with SRS or neurosurgery with or without WBRT. Of the 50 baseline FACT-Br items, only five items (I feel ill; I get support from my friends; I worry about dying; I have difficulty expressing my thoughts, I am able to put my thoughts into action) were statistically worse in patients treated with WBRT alone (P<0.05). Patients who received SRS or surgery with or without WBRT had statistically (P<0.05) higher scores for the FWB domain, additional concerns domain, and FACT-G total scores, indicating better QOL. Patients selected for WBRT alone reported statistically different baseline QOL as compared to patients who were treated with SRS or neurosurgery (with or without WBRT).

  7. Tomographic Imaging of a Forested Area By Airborne Multi-Baseline P-Band SAR.

    PubMed

    Frey, Othmar; Morsdorf, Felix; Meier, Erich

    2008-09-24

    In recent years, various attempts have been undertaken to obtain information about the structure of forested areas from multi-baseline synthetic aperture radar data. Tomographic processing of such data has been demonstrated for airborne L-band data but the quality of the focused tomographic images is limited by several factors. In particular, the common Fourierbased focusing methods are susceptible to irregular and sparse sampling, two problems, that are unavoidable in case of multi-pass, multi-baseline SAR data acquired by an airborne system. In this paper, a tomographic focusing method based on the time-domain back-projection algorithm is proposed, which maintains the geometric relationship between the original sensor positions and the imaged target and is therefore able to cope with irregular sampling without introducing any approximations with respect to the geometry. The tomographic focusing quality is assessed by analysing the impulse response of simulated point targets and an in-scene corner reflector. And, in particular, several tomographic slices of a volume representing a forested area are given. The respective P-band tomographic data set consisting of eleven flight tracks has been acquired by the airborne E-SAR sensor of the German Aerospace Center (DLR).

  8. So Tired: Predictive Utility of Baseline Sleep Screening in a Longitudinal Observational Survey Cohort of First-Year Residents.

    PubMed

    Zebrowski, Jonathan P; Pulliam, Samantha J; Denninger, John W; Berkowitz, Lori R

    2018-06-01

    Sleep impairment is highly prevalent among resident physicians and is associated with both adverse patient outcomes and poor resident mental and physical health. Risk factors for sleep problems during residency are less clear, and no screening model exists to identify residents at risk for sleep impairment. The objective of this study was to assess change in resident sleep during training and to evaluate utility of baseline sleep screening in predicting future sleep impairment. This is a prospective observational repeated-measures survey study. The participants comprised PGY-1 residents across multiple specialties at Partners HealthCare hospitals. Main measures used for this study were demographic queries and two validated scales: the Pittsburgh Sleep Quality Index (PSQI), measuring sleep quality, and the Epworth Sleepiness Scale (ESS), measuring excessive daytime sleepiness. Two hundred eighty-one PGY-1 residents completed surveys at residency orientation, and 153 (54%) completed matched surveys 9 months later. Mean nightly sleep time decreased from 7.6 to 6.5 hours (p < 0.001). Mean PSQI score increased from 3.6 to 5.2 (p < 0.001), and mean ESS score increased from 7.2 to 10.4 (p < 0.001). The proportion of residents exceeding the scales' clinical cutoffs increased over time from 15 to 40% on the PSQI (p < 0.001) and from 26 to 59% on the ESS (p < 0.001). Baseline normal sleep was not protective: 68% of residents with normal scores on both scales at baseline exceeded the clinical cutoff on at least one scale at follow-up. Greater age and fewer children increased follow-up PSQI score (p < 0.001) but not ESS score. During PGY-1 training, residents experience worsening sleep duration, quality of sleep, and daytime sleepiness. Residents with baseline impaired sleep tend to remain impaired. Moreover, many residents with baseline normal sleep experience sleep deterioration over time. Sleep screening at residency orientation may identify some

  9. The London low emission zone baseline study.

    PubMed

    Kelly, Frank; Armstrong, Ben; Atkinson, Richard; Anderson, H Ross; Barratt, Ben; Beevers, Sean; Cook, Derek; Green, Dave; Derwent, Dick; Mudway, Ian; Wilkinson, Paul

    2011-11-01

    On February 4, 2008, the world's largest low emission zone (LEZ) was established. At 2644 km2, the zone encompasses most of Greater London. It restricts the entry of the oldest and most polluting diesel vehicles, including heavy-goods vehicles (haulage trucks), buses and coaches, larger vans, and minibuses. It does not apply to cars or motorcycles. The LEZ scheme will introduce increasingly stringent Euro emissions standards over time. The creation of this zone presented a unique opportunity to estimate the effects of a stepwise reduction in vehicle emissions on air quality and health. Before undertaking such an investigation, robust baseline data were gathered on air quality and the oxidative activity and metal content of particulate matter (PM) from air pollution monitors located in Greater London. In addition, methods were developed for using databases of electronic primary-care records in order to evaluate the zone's health effects. Our study began in 2007, using information about the planned restrictions in an agreed-upon LEZ scenario and year-on-year changes in the vehicle fleet in models to predict air pollution concentrations in London for the years 2005, 2008, and 2010. Based on this detailed emissions and air pollution modeling, the areas in London were then identified that were expected to show the greatest changes in air pollution concentrations and population exposures after the implementation of the LEZ. Using these predictions, the best placement of a pollution monitoring network was determined and the feasibility of evaluating the health effects using electronic primary-care records was assessed. To measure baseline pollutant concentrations before the implementation of the LEZ, a comprehensive monitoring network was established close to major roadways and intersections. Output-difference plots from statistical modeling for 2010 indicated seven key areas likely to experience the greatest change in concentrations of nitrogen dioxide (NO2) (at least 3

  10. FAQs about Baseline Testing among Young Athletes

    MedlinePlus

    ... your league prepare for concussions both pre- and post-season. What is baseline testing? Baseline testing is a pre-season exam conducted by a trained health care professional. Baseline tests are used to assess an athlete’s balance and ...

  11. Environmental baseline conditions for impact assessment of unconventional gas exploitation: the G-Baseline project

    NASA Astrophysics Data System (ADS)

    Kloppmann, Wolfram; Mayer, Berhard; Millot, Romain; Parker, Beth L.; Gaucher, Eric; Clarkson, Christopher R.; Cherry, John A.; Humez, Pauline; Cahill, Aaron

    2015-04-01

    A major scientific challenge and an indispensible prerequisite for environmental impact assessment in the context of unconventional gas development is the determination of the baseline conditions against which potential environmental impacts on shallow freshwater resources can be accurately and quantitatively tested. Groundwater and surface water resources overlying the low-permeability hydrocarbon host rocks containing shale gas may be impacted to different extents by naturally occurring saline fluids and by natural gas emanations. Baseline assessments in areas of previous conventional hydrocarbon production may also reveal anthropogenic impacts from these activities not related to unconventional gas development. Once unconventional gas exploitation has started, the baseline may be irrevocably lost by the intricate superposition of geogenic and potential anthropogenic contamination by stray gas, formation waters and chemicals used during hydraulic fracturing. The objective of the Franco-Canadian NSERC-ANR project G-Baseline is to develop an innovative and comprehensive methodology of geochemical and isotopic characterization of the environmental baseline for water and gas samples from all three essential zones: (1) the production zone, including flowback waters, (2) the intermediate zone comprised of overlying formations, and (3) shallow aquifers and surface water systems where contamination may result from diverse natural or human impacts. The outcome will be the establishment of a methodology based on innovative tracer and monitoring techniques, including traditional and non-traditional isotopes (C, H, O, S, B, Sr, Cl, Br, N, U, Li, Cu, Zn, CSIA...) for detecting, quantifying and modeling of potential leakage of stray gas and of saline formation water mixed with flowback fluids into fresh groundwater resources and surface waters taking into account the pathways and mechanisms of fluid and gas migration. Here we present an outline of the project as well as first

  12. Making Quality Health Websites a National Public Health Priority: Toward Quality Standards

    PubMed Central

    2016-01-01

    Background Most US adults have limited health literacy skills. They struggle to understand complex health information and services and to make informed health decisions. The Internet has quickly become one of the most popular places for people to search for information about their health, thereby making access to quality information on the Web a priority. However, there are no standardized criteria for evaluating Web-based health information. Every 10 years, the US Department of Health and Human Services' Office of Disease Prevention and Health Promotion (ODPHP) develops a set of measurable objectives for improving the health of the nation over the coming decade, known as Healthy People. There are two objectives in Healthy People 2020 related to website quality. The first is objective Health Communication and Health Information Technology (HC/HIT) 8.1: increase the proportion of health-related websites that meet 3 or more evaluation criteria for disclosing information that can be used to assess information reliability. The second is objective HC/HIT-8.2: increase the proportion of health-related websites that follow established usability principles. Objective The ODPHP conducted a nationwide assessment of the quality of Web-based health information using the Healthy People 2020 objectives. The ODPHP aimed to establish (1) a standardized approach to defining and measuring the quality of health websites; (2) benchmarks for measurement; (3) baseline data points to capture the current status of website quality; and (4) targets to drive improvement. Methods The ODPHP developed the National Quality Health Website Survey instrument to assess the quality of health-related websites. The ODPHP used this survey to review 100 top-ranked health-related websites in order to set baseline data points for these two objectives. The ODPHP then set targets to drive improvement by 2020. Results This study reviewed 100 health-related websites. For objective HC/HIT-8.1, a total of 58 out

  13. Environmental baselines: preparing for shale gas in the UK

    NASA Astrophysics Data System (ADS)

    Bloomfield, John; Manamsa, Katya; Bell, Rachel; Darling, George; Dochartaigh, Brighid O.; Stuart, Marianne; Ward, Rob

    2014-05-01

    Groundwater is a vital source of freshwater in the UK. It provides almost 30% of public water supply on average, but locally, for example in south-east England, it is constitutes nearly 90% of public supply. In addition to public supply, groundwater has a number of other uses including agriculture, industry, and food and drink production. It is also vital for maintaining river flows especially during dry periods and so is essential for maintaining ecosystem health. Recently, there have been concerns expressed about the potential impacts of shale gas development on groundwater. The UK has abundant shales and clays which are currently the focus of considerable interest and there is active research into their characterisation, resource evaluation and exploitation risks. The British Geological Survey (BGS) is undertaking research to provide information to address some of the environmental concerns related to the potential impacts of shale gas development on groundwater resources and quality. The aim of much of this initial work is to establish environmental baselines, such as a baseline survey of methane occurrence in groundwater (National methane baseline study) and the spatial relationships between potential sources and groundwater receptors (iHydrogeology project), prior to any shale gas exploration and development. The poster describes these two baseline studies and presents preliminary findings. BGS are currently undertaking a national survey of baseline methane concentrations in groundwater across the UK. This work will enable any potential future changes in methane in groundwater associated with shale gas development to be assessed. Measurements of methane in potable water from the Cretaceous, Jurassic and Triassic carbonate and sandstone aquifers are variable and reveal methane concentrations of up to 500 micrograms per litre, but the mean value is relatively low at < 10 micrograms per litre. These values compare with much higher levels of methane in aquicludes

  14. 48 CFR 1334.202 - Integrated baseline reviews.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 1334.202 Integrated baseline reviews. An Integrated Baseline Review shall be conducted when an Earned Value Management System... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Integrated baseline...

  15. 48 CFR 1334.202 - Integrated baseline reviews.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 1334.202 Integrated baseline reviews. An Integrated Baseline Review shall be conducted when an Earned Value Management System... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Integrated baseline...

  16. 48 CFR 1334.202 - Integrated baseline reviews.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 1334.202 Integrated baseline reviews. An Integrated Baseline Review shall be conducted when an Earned Value Management System... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Integrated baseline...

  17. 48 CFR 1334.202 - Integrated baseline reviews.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 1334.202 Integrated baseline reviews. An Integrated Baseline Review shall be conducted when an Earned Value Management System... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Integrated baseline...

  18. 48 CFR 1334.202 - Integrated baseline reviews.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 1334.202 Integrated baseline reviews. An Integrated Baseline Review shall be conducted when an Earned Value Management System... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Integrated baseline...

  19. Language experience narratives and the role of autobiographical reasoning in becoming an urban science teacher

    NASA Astrophysics Data System (ADS)

    Rivera Maulucci, Maria S.

    2011-06-01

    One of the central challenges globalization and immigration present to education is how to construct school language policies, procedures, and curricula to support academic success of immigrant youth. This case-study compares and contrasts language experience narratives along Elena's developmental trajectory of becoming an urban science teacher. Elena reflects upon her early language experiences and her more recent experiences as a preservice science teacher in elementary dual language classrooms. The findings from Elena's early schooling experiences provide an analysis of the linkages between Elena's developing English proficiency, her Spanish proficiency, and her autobiographical reasoning. Elena's experiences as a preservice teacher in two elementary dual language classrooms indicates ways in which those experiences helped to reframe her views about the intersections between language learning and science learning. I propose the language experience narrative, as a subset of the life story, as a way to understand how preservice teachers reconstruct past language experiences, connect to the present, and anticipate future language practices.

  20. Links between early baseline cortisol, attachment classification, and problem behaviors: A test of differential susceptibility versus diathesis-stress.

    PubMed

    Fong, Michelle C; Measelle, Jeffrey; Conradt, Elisabeth; Ablow, Jennifer C

    2017-02-01

    The purpose of the current study was to predict concurrent levels of problem behaviors from young children's baseline cortisol and attachment classification, a proxy for the quality of caregiving experienced. In a sample of 58 children living at or below the federal poverty threshold, children's baseline cortisol levels, attachment classification, and problem behaviors were assessed at 17 months of age. We hypothesized that an interaction between baseline cortisol and attachment classification would predict problem behaviors above and beyond any main effects of baseline cortisol and attachment. However, based on limited prior research, we did not predict whether or not this interaction would be more consistent with diathesis-stress or differential susceptibility models. Consistent with diathesis-stress theory, the results indicated no significant differences in problem behavior levels among children with high baseline cortisol. In contrast, children with low baseline cortisol had the highest level of problem behaviors in the context of a disorganized attachment relationship. However, in the context of a secure attachment relationship, children with low baseline cortisol looked no different, with respect to problem behavior levels, then children with high cortisol levels. These findings have substantive implications for the socioemotional development of children reared in poverty. Copyright © 2017 Elsevier Inc. All rights reserved.

  1. Estimating mean QALYs in trial-based cost-effectiveness analysis: the importance of controlling for baseline utility.

    PubMed

    Manca, Andrea; Hawkins, Neil; Sculpher, Mark J

    2005-05-01

    In trial-based cost-effectiveness analysis baseline mean utility values are invariably imbalanced between treatment arms. A patient's baseline utility is likely to be highly correlated with their quality-adjusted life-years (QALYs) over the follow-up period, not least because it typically contributes to the QALY calculation. Therefore, imbalance in baseline utility needs to be accounted for in the estimation of mean differential QALYs, and failure to control for this imbalance can result in a misleading incremental cost-effectiveness ratio. This paper discusses the approaches that have been used in the cost-effectiveness literature to estimate absolute and differential mean QALYs alongside randomised trials, and illustrates the implications of baseline mean utility imbalance for QALY calculation. Using data from a recently conducted trial-based cost-effectiveness study and a micro-simulation exercise, the relative performance of alternative estimators is compared, showing that widely used methods to calculate differential QALYs provide incorrect results in the presence of baseline mean utility imbalance regardless of whether these differences are formally statistically significant. It is demonstrated that multiple regression methods can be usefully applied to generate appropriate estimates of differential mean QALYs and an associated measure of sampling variability, while controlling for differences in baseline mean utility between treatment arms in the trial. Copyright 2004 John Wiley & Sons, Ltd

  2. Level 1 Water-Quality Inventory of Baseline Levels of Pesticides in Urban Creeks - Golden Gate National Recreation Area and the Presidio of San Francisco, California

    USGS Publications Warehouse

    Hladik, Michelle; Orlando, James L.

    2008-01-01

    To characterize baseline water-quality levels of pesticides in Golden Gate National Recreation Area and the Presidio of San Francisco, the U.S. Geological Survey collected and analyzed surface-water and bed-sediment samples at 10 creeks during February, April, and July 2006. Pesticide data were obtained using previously developed methods. Samples from sites in the Presidio were analyzed only for pyrethroid insecticides, whereas the remaining samples were analyzed for pyrethroids and additional current and historical-use pesticides. Pesticide concentrations were low in both the water (below 30 ng/L) and sediment (below 3 ng/g). The pyrethroid bifenthrin was detected in water samples from two sites at concentrations below 2 ng/L. Other compounds detected in water included the herbicides dacthal (DCPA) and prometryn, the insecticide fipronil, the insecticide degradates p,p'-DDE and fipronil sulfone, and the fungicides cyproconazole, myclobutanil and tetraconazole. The only pesticides detected in the sediment samples were p,p'-DDT and its degradates (p,p'-DDD and p,p'-DDE). Pesticide information from the samples collected can provide a reference point for future sampling and can help National Park Service managers assess the water quality of the urban creeks.

  3. 40 CFR 80.92 - Baseline auditor requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false Baseline auditor requirements. 80.92... (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Anti-Dumping § 80.92 Baseline auditor requirements. (a... determination methodology, resulting baseline fuel parameter, volume and emissions values verified by an auditor...

  4. 10 CFR 850.20 - Baseline beryllium inventory.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Baseline beryllium inventory. 850.20 Section 850.20 Energy... Baseline beryllium inventory. (a) The responsible employer must develop a baseline inventory of the locations of beryllium operations and other locations of potential beryllium contamination, and identify the...

  5. Hydrology and water quality in two mountain basins of the northeastern US: Assessing baseline conditions and effects of ski area development

    USGS Publications Warehouse

    Wemple, B.; Shanley, J.; Denner, J.; Ross, D.; Mills, K.

    2007-01-01

    Mountain regions throughout the world face intense development pressures associated with recreational and tourism uses. Despite these pressures, much of the research on bio-geophysical impacts of humans in mountain regions has focused on the effects of natural resource extraction. This paper describes findings from the first 3 years of a study examining high elevation watershed processes in a region undergoing alpine resort development. Our study is designed as a paired-watershed experiment. The Ranch Brook watershed (9.6 km2) is a relatively pristine, forested watershed and serves as the undeveloped 'control' basin. West Branch (11.7 km2) encompasses an existing alpine ski resort, with approximately 17% of the basin occupied by ski trails and impervious surfaces, and an additional 7% slated for clearing and development. Here, we report results for water years 2001-2003 of streamflow and water quality dynamics for these watersheds. Precipitation increases significantly with elevation in the watersheds, and winter precipitation represents 36-46% of annual precipitation. Artificial snowmaking from water within West Branch watershed currently augments annual precipitation by only 3-4%. Water yield in the developed basin exceeded that in the control by 18-36%. Suspended sediment yield was more than two and a half times greater and fluxes of all major solutes were higher in the developed basin. Our study is the first to document the effects of existing ski area development on hydrology and water quality in the northeastern US and will serve as an important baseline for evaluating the effects of planned resort expansion activities in this area.

  6. 33 CFR 2.20 - Territorial sea baseline.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 1 2012-07-01 2012-07-01 false Territorial sea baseline. 2.20... JURISDICTION Jurisdictional Terms § 2.20 Territorial sea baseline. Territorial sea baseline means the line defining the shoreward extent of the territorial sea of the United States drawn according to the principles...

  7. 33 CFR 2.20 - Territorial sea baseline.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Territorial sea baseline. 2.20... JURISDICTION Jurisdictional Terms § 2.20 Territorial sea baseline. Territorial sea baseline means the line defining the shoreward extent of the territorial sea of the United States drawn according to the principles...

  8. 33 CFR 2.20 - Territorial sea baseline.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Territorial sea baseline. 2.20... JURISDICTION Jurisdictional Terms § 2.20 Territorial sea baseline. Territorial sea baseline means the line defining the shoreward extent of the territorial sea of the United States drawn according to the principles...

  9. 33 CFR 2.20 - Territorial sea baseline.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 1 2013-07-01 2013-07-01 false Territorial sea baseline. 2.20... JURISDICTION Jurisdictional Terms § 2.20 Territorial sea baseline. Territorial sea baseline means the line defining the shoreward extent of the territorial sea of the United States drawn according to the principles...

  10. 33 CFR 2.20 - Territorial sea baseline.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 1 2014-07-01 2014-07-01 false Territorial sea baseline. 2.20... JURISDICTION Jurisdictional Terms § 2.20 Territorial sea baseline. Territorial sea baseline means the line defining the shoreward extent of the territorial sea of the United States drawn according to the principles...

  11. Baseline program

    NASA Technical Reports Server (NTRS)

    Roberts, Barney B.; Vonputtkamer, Jesco

    1992-01-01

    This assumed program was developed from several sources of information and is extrapolated over future decades using a set of reasonable assumptions based on incremental growth. The assumptions for the NASA baseline program are as follows: balanced emphasis in four domains; a constant level of activity; low to moderate real budget growth; maximum use of commonality; and realistic and practical technology development. The first domain is low Earth Orbit (LEO). Activities there are concentrated on the space station but extend on one side to Earth-pointing sensors for unmanned platforms and on the other to the launch and staging of unmanned solar system exploration missions. The second domain is geosynchronous Earth orbit (GEO) and cislunar space. Activities here include all GEO missions and operations, both unmanned and manned, and all transport of materials and crews between LEO and the vicinity of the Moon. The third domain is the Moon itself. Lunar activities are to include both orbiting and landing missions; the landings may be either unmanned or manned. The last domain is Mars. Missions to Mars will initially be unmanned but they will eventually be manned. Program elements and descriptions are discussed as are critiques of the NASA baseline.

  12. Sulfur and carbon geochemistry of the Santa Elena peridotites: Comparing oceanic and continental processes during peridotite alteration

    NASA Astrophysics Data System (ADS)

    Schwarzenbach, Esther M.; Gill, Benjamin C.; Gazel, Esteban; Madrigal, Pilar

    2016-05-01

    Ultramafic rocks exposed on the continent serve as a window into oceanic and continental processes of water-peridotite interaction, so called serpentinization. In both environments there are active carbon and sulfur cycles that contain abiogenic and biogenic processes, which are eventually imprinted in the geochemical signatures of the basement rocks and the calcite and magnesite deposits associated with fluids that issue from these systems. Here, we present the carbon and sulfur geochemistry of ultramafic rocks and carbonate deposits from the Santa Elena ophiolite in Costa Rica. The aim of this study is to leverage the geochemistry of the ultramafic sequence and associated deposits to distinguish between processes that were dominant during ocean floor alteration and those dominant during low-temperature, continental water-peridotite interaction. The peridotites are variably serpentinized with total sulfur concentrations up to 877 ppm that is typically dominated by sulfide over sulfate. With the exception of one sample the ultramafic rocks are characterized by positive δ34Ssulfide (up to + 23.1‰) and δ34Ssulfate values (up to + 35.0‰). Carbon contents in the peridotites are low and are isotopically distinct from typical oceanic serpentinites. In particular, δ13C of the inorganic carbon suggests that the carbon is not derived from seawater, but rather the product of the interaction of meteoric water with the ultramafic rocks. In contrast, the sulfur isotope data from sulfide minerals in the peridotites preserve evidence for interaction with a hydrothermal fluid. Specifically, they indicate closed system abiogenic sulfate reduction suggesting that oceanic serpentinization occurred with limited input of seawater. Overall, the geochemical signatures preserve evidence for both oceanic and continental water-rock interaction with the majority of carbon (and possibly sulfate) being incorporated during continental water-rock interaction. Furthermore, there is

  13. Improving quality of care in general practices by self-audit, benchmarking and quality circles.

    PubMed

    Mahlknecht, Angelika; Abuzahra, Muna E; Piccoliori, Giuliano; Enthaler, Nina; Engl, Adolf; Sönnichsen, Andreas

    2016-10-01

    Guideline adherence of general practitioners (GP) regarding treatment of chronic conditions shows room for improvement. Thus, concepts have to be designed to promote quality of care. The aim of the interventional study "Improvement of Quality by Benchmarking" was to assess whether quality can be improved by self-auditing, benchmarking and quality circles in Salzburg (Austria) and South Tyrol (Italy). In this publication we present the Austrian results. Quality indicators were developed in a consensus process for eight chronic diseases based on pre-existing quality management systems. A quality score consisting of 35 indicators was calculated (0-5 points per indicator depending on fulfilment, maximum 175 points). Data were extracted from the electronic health records of participating practices in 2012, 2013 and 2014. A statistical pre-post analysis was performed using Wilcoxon signed-rank tests. A total of 20 GPs participated in the project. The mean quality score increased from 62.0 at baseline to 84.0 at the second follow-up (p = 0.003). Regarding the individual quality indicators, strong improvements were achieved between baseline and first follow-up, especially in process indicators concerning documentation. Between the first and second follow-up, quality remained in most cases at the same level. The validity of results is limited because of structural and technical problems. Due to the uncontrolled pre-post design we cannot exclude external influences on the results. Nevertheless, the intervention was able to improve measured quality of care. Barriers were detected that should be considered in a possible implementation of quality control programs.

  14. Frontline staff motivation levels and health care quality in rural and urban primary health facilities: a baseline study in the Greater Accra and Western regions of Ghana.

    PubMed

    Alhassan, Robert Kaba; Nketiah-Amponsah, Edward

    2016-12-01

    The population of Ghana is increasingly becoming urbanized with about 70 % of the estimated 26.9 million people living in urban and peri-urban areas. Nonetheless, eight out of the ten regions in Ghana remain predominantly rural where only 32.1 % of the national health sector workforce works. Doctor-patient ratio in a predominantly rural region is about 1:18,257 compared to 1:4,099 in an urban region. These rural-urban inequities significantly account for the inability of Ghana to attain the health related Millennium Development Goals (MDGs) before the end of 2015. To ascertain whether or not rural-urban differences exist in health worker motivation levels and quality of health care in health facilities accredited by the National Health Insurance Authority in Ghana. This is a baseline quantitative study conducted in 2012 among 324 health workers in 64 accredited clinics located in 9 rural and 7 urban districts in Ghana. Ordered logistic regression was performed to determine the relationship between facility geographic location (rural/urban) and staff motivation levels, and quality health care standards. Quality health care and patient safety standards were averagely low in the sampled health facilities. Even though health workers in rural facilities were more de-motivated by poor availability of resources and drugs than their counterparts in urban facilities (p < 0.05), quality of health care and patient safety standards were relatively better in rural facilities. For Ghana to attain the newly formulated sustainable development goals on health, there is the need for health authorities to address the existing rural-urban imbalances in health worker motivation and quality health care standards in primary healthcare facilities. Future studies should compare staff motivation levels and quality standards in accredited and non-accredited health facilities since the current study was limited to health facilities accredited by the National Health Insurance Authority.

  15. WEST VIRGINIA BASELINE

    EPA Science Inventory

    This report was prepared as part of the Ohio River Basin Energy Study (ORBES), a multidisciplinary policy research program supported by the Environmental Protection Agency. Its purpose is to provide baseline information on West Virginia, one of six states included partly or total...

  16. Baseline tests for arc melter vitrification of INEL buried wastes. Volume II: Baseline test data appendices

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Oden, L.L.; O`Conner, W.K.; Turner, P.C.

    1993-11-19

    This report presents field results and raw data from the Buried Waste Integrated Demonstration (BWID) Arc Melter Vitrification Project Phase 1 baseline test series conducted by the Idaho National Engineering Laboratory (INEL) in cooperation with the U.S. Bureau of Mines (USBM). The baseline test series was conducted using the electric arc melter facility at the USBM Albany Research Center in Albany, Oregon. Five different surrogate waste feed mixtures were tested that simulated thermally-oxidized, buried, TRU-contaminated, mixed wastes and soils present at the INEL. The USBM Arc Furnace Integrated Waste Processing Test Facility includes a continuous feed system, the arc meltingmore » furnace, an offgas control system, and utilities. The melter is a sealed, 3-phase alternating current (ac) furnace approximately 2 m high and 1.3 m wide. The furnace has a capacity of 1 metric ton of steel and can process as much as 1,500 lb/h of soil-type waste materials. The surrogate feed materials included five mixtures designed to simulate incinerated TRU-contaminated buried waste materials mixed with INEL soil. Process samples, melter system operations data and offgas composition data were obtained during the baseline tests to evaluate the melter performance and meet test objectives. Samples and data gathered during this program included (a) automatically and manually logged melter systems operations data, (b) process samples of slag, metal and fume solids, and (c) offgas composition, temperature, velocity, flowrate, moisture content, particulate loading and metals content. This report consists of 2 volumes: Volume I summarizes the baseline test operations. It includes an executive summary, system and facility description, review of the surrogate waste mixtures, and a description of the baseline test activities, measurements, and sample collection. Volume II contains the raw test data and sample analyses from samples collected during the baseline tests.« less

  17. Dietary and physical activity behaviors related to obesity-specific quality of life and work productivity: baseline results from a worksite trial

    PubMed Central

    Cash, Stephanie Whisnant; Beresford, Shirley A.A; Henderson, Jo Ann; McTiernan, Anne; Xiao, Liren; Wang, C.Y.; Patrick, Donald L.

    2012-01-01

    Obesity is associated with impaired health-related quality of life (QoL) and reduced productivity; less is known about the effect of dietary factors. This study investigated how dietary behaviors, physical activity, and Body Mass Index (BMI) relate to weight-specific QoL and work productivity. The study was conducted in 31 small blue-collar and service industry worksites in Seattle. Participants were 747 employees (33.5% non-White). Measures included self-reported servings of fruits and vegetables, dietary behaviors such as fast food consumption, Godin free-time physical activity scores, measured height and weight, Obesity and Weight Loss Quality of Life (OWLQOL) scores, and Work Limitations Questionnaire (WLQ) scores. Baseline data were analyzed using linear mixed models separately for men (n=348) and women (n=399), since gender modified the effects. BMI was negatively associated with OWLQOL in both women (p<0.001) and men (p<0.001). The linear effect estimate for OWLQOL score associated with one-category increase in BMI was 30% (95% CI: 25%, 44%) for women and 14% (95% CI: 10%, 17%) for men. BMI was positively associated with productivity loss only in women (exp(slope)=1.46, 95% CI: 1.02, 2.11, p=0.04). Eating while doing another activity was negatively associated with OWLQOL scores in men (p=0.0006, independent of BMI) and with productivity in women (p=0.04, effect diminished when adjusting for BMI). Fast food meals were associated with decreased productivity for men (p=0.038, independent of BMI). Results suggest the obesogenic dietary behaviors and higher BMI are associated with decreased QoL and productivity variously in women and men. PMID:22142517

  18. Bayesian Inference of Baseline Fertility and Treatment Effects via a Crop Yield-Fertility Model

    PubMed Central

    Chen, Hungyen; Yamagishi, Junko; Kishino, Hirohisa

    2014-01-01

    To effectively manage soil fertility, knowledge is needed of how a crop uses nutrients from fertilizer applied to the soil. Soil quality is a combination of biological, chemical and physical properties and is hard to assess directly because of collective and multiple functional effects. In this paper, we focus on the application of these concepts to agriculture. We define the baseline fertility of soil as the level of fertility that a crop can acquire for growth from the soil. With this strict definition, we propose a new crop yield-fertility model that enables quantification of the process of improving baseline fertility and the effects of treatments solely from the time series of crop yields. The model was modified from Michaelis-Menten kinetics and measured the additional effects of the treatments given the baseline fertility. Using more than 30 years of experimental data, we used the Bayesian framework to estimate the improvements in baseline fertility and the effects of fertilizer and farmyard manure (FYM) on maize (Zea mays), barley (Hordeum vulgare), and soybean (Glycine max) yields. Fertilizer contributed the most to the barley yield and FYM contributed the most to the soybean yield among the three crops. The baseline fertility of the subsurface soil was very low for maize and barley prior to fertilization. In contrast, the baseline fertility in this soil approximated half-saturated fertility for the soybean crop. The long-term soil fertility was increased by adding FYM, but the effect of FYM addition was reduced by the addition of fertilizer. Our results provide evidence that long-term soil fertility under continuous farming was maintained, or increased, by the application of natural nutrients compared with the application of synthetic fertilizer. PMID:25405353

  19. The Effects of Baseline Estimation on the Reliability, Validity, and Precision of CBM-R Growth Estimates

    ERIC Educational Resources Information Center

    Van Norman, Ethan R.; Christ, Theodore J.; Zopluoglu, Cengiz

    2013-01-01

    This study examined the effect of baseline estimation on the quality of trend estimates derived from Curriculum Based Measurement of Oral Reading (CBM-R) progress monitoring data. The authors used a linear mixed effects regression (LMER) model to simulate progress monitoring data for schedules ranging from 6-20 weeks for datasets with high and low…

  20. Influences on diet quality in older age: the importance of social factors.

    PubMed

    Bloom, Ilse; Edwards, Mark; Jameson, Karen A; Syddall, Holly E; Dennison, Elaine; Gale, Catharine R; Baird, Janis; Cooper, Cyrus; Aihie Sayer, Avan; Robinson, Sian

    2017-03-01

    poor diet quality is common among older people, but little is known about influences on food choice, including the role of psychosocial factors at this age. to identify psychosocial correlates of diet quality in a community-dwelling population of men and women aged 59-73 years; to describe relationships with change in diet quality over 10 years. Longitudinal cohort, Hertfordshire Cohort Study (HCS). HCS participants assessed at baseline (1998-2003: 1,048 men, 862 women); 183 men and 189 women re-assessed in 2011. diet was assessed by administered food frequency questionnaire; diet scores were calculated to describe diet quality at baseline and follow-up. A range of psychosocial factors (social support, social network, participation in leisure activities, depression and anxiety, sense of control) were assessed by questionnaire. at baseline, better diet quality was related to a range of social factors, including increased confiding/emotional social support (men and women), practical support (men) and a larger social network (women) (all P < 0.05). For both men and women, greater participation in social and cognitive leisure activities was related to better diet quality (P < 0.005). There were few associations between measured psychosocial factors at baseline and change in diet score over 10 years, in the follow-up sub-group. However, greater participation in leisure activities, especially cognitive activities, at baseline was associated with smaller declines in diet quality over the 10-year follow-up period for both men (P = 0.017) and women (P = 0.014). in community-dwelling older adults, a range of social factors, that includes greater participation in leisure activities, were associated with diets of better quality. © The Author 2016. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For Permissions, please email: journals.permissions@oup.com

  1. Predicting future learning from baseline network architecture.

    PubMed

    Mattar, Marcelo G; Wymbs, Nicholas F; Bock, Andrew S; Aguirre, Geoffrey K; Grafton, Scott T; Bassett, Danielle S

    2018-05-15

    Human behavior and cognition result from a complex pattern of interactions between brain regions. The flexible reconfiguration of these patterns enables behavioral adaptation, such as the acquisition of a new motor skill. Yet, the degree to which these reconfigurations depend on the brain's baseline sensorimotor integration is far from understood. Here, we asked whether spontaneous fluctuations in sensorimotor networks at baseline were predictive of individual differences in future learning. We analyzed functional MRI data from 19 participants prior to six weeks of training on a new motor skill. We found that visual-motor connectivity was inversely related to learning rate: sensorimotor autonomy at baseline corresponded to faster learning in the future. Using three additional scans, we found that visual-motor connectivity at baseline is a relatively stable individual trait. These results suggest that individual differences in motor skill learning can be predicted from sensorimotor autonomy at baseline prior to task execution. Copyright © 2018 The Author(s). Published by Elsevier Inc. All rights reserved.

  2. Recent progress of laser spectroscopy experiments on antiprotonic helium

    NASA Astrophysics Data System (ADS)

    Hori, Masaki

    2018-03-01

    The Atomic Spectroscopy and Collisions Using Slow Antiprotons (ASACUSA) collaboration is currently carrying out laser spectroscopy experiments on antiprotonic helium ? atoms at CERN's Antiproton Decelerator facility. Two-photon spectroscopic techniques have been employed to reduce the Doppler width of the measured ? resonance lines, and determine the atomic transition frequencies to a fractional precision of 2.3-5 parts in 109. More recently, single-photon spectroscopy of buffer-gas cooled ? has reached a similar precision. By comparing the results with three-body quantum electrodynamics calculations, the antiproton-to-electron mass ratio was determined as ?, which agrees with the known proton-to-electron mass ratio with a precision of 8×10-10. The high-quality antiproton beam provided by the future Extra Low Energy Antiproton Ring (ELENA) facility should enable further improvements in the experimental precision. This article is part of the Theo Murphy meeting issue `Antiproton physics in the ELENA era'.

  3. [The Octabaix study. Baseline assessment and 5 years of follow-up].

    PubMed

    Ferrer, Assumpta; Formiga, Francesc; Padrós, Gloria; Badia, Teresa; Almeda, Jesús; Octabaix, Grupo Estudio

    This is a review of a prospective, community-based study with a follow-up period of 5years. It is a study of 328 participants aged 85 at baseline, of which 62% were female, 53% widows, and a third of them living alone. High blood pressure was observed in 75.9%, dyslipidaemia in 51.2%, and diabetes in 17.7%. At baseline the median Barthel Index was 95, the Spanish version of the Mini-Mental State Examination was 28, the Charlson index 1, the Mini Nutritional Assessment 25, the Gijón test 10, the visual analogue scale of the Quality of Life Test was 60, and with a mean of 6.1 prescription drugs. A lower quality of life was also associated with female gender, a phenotype of frailty, heart failure, and a high level of social risk. At 5years of follow-up, the mortality rate was high, with 138 (42.1%) of the population sample dying at the end of the period. It represents an annual mortality rate of 8.4%. Thus, a common denominator of this review has been the high importance of functionality and overall comorbidity factors associated with mortality in this very old age group, compared to other more traditional factors in younger populations. Several studies of frailty have also been assessed in this group, as well as falls, nutritional risk, diabetes and successful aging, including important aspects to better understand this population group. Copyright © 2016 SEGG. Publicado por Elsevier España, S.L.U. All rights reserved.

  4. Differences in Symptom Reporting Between Males and Females at Baseline and After a Sports-Related Concussion: A Systematic Review and Meta-Analysis.

    PubMed

    Brown, Dana A; Elsass, Julie A; Miller, Ashley J; Reed, Lauren E; Reneker, Jennifer C

    2015-07-01

    Concussion literature and treatment guidelines are inconclusive regarding the role of sex in symptom reporting at baseline and post-concussion. Although empirical evidence is lacking, it is generally regarded that females have a more severe symptomatic presentation than males at all time-points on the concussion spectrum. Our objective was to determine whether differences exist between males and females at baseline (pre-season/before concussion) or post-concussion for self-reported (1) prevalence of individual symptoms and (2) total symptom scores in high school and college athletes. Systematic review and meta-analysis of observational cohort studies; level of evidence, 1. A computerized search of the PubMed, SPORTDiscus, CINAHL, and Scopus databases was performed. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) guidelines were followed. Criteria for inclusion were (1) self-report of symptoms at any time within the concussion spectrum, including baseline and after concussion, (2) study sample included high school and/or collegiate athletes aged 12-26 years, (3) concussions occurred during participation in sport, and (4) symptom reporting was separated by sex. The Quality Assessment Tool for Cohort Studies, Q-Coh, was utilized for quality assessment. Twenty-one studies met the criteria for inclusion: seventeen had good quality and four, acceptable quality. At baseline, females had significantly higher odds than males of reporting the individual symptoms of vision/hearing problems, headache/migraine, difficulty concentrating, energy/sleep disturbances, and emotional disturbances. Post-concussion, only one symptom demonstrated significant differences between males and females, with females demonstrating lower odds of reporting confusion than males. Statistically, at baseline and post-concussion, females had significantly higher total symptom scores on the Post-Concussion Scale (PCS) and the Sport Concussion Assessment Tool 2 (SCAT2), but when the

  5. ALMA long baseline phase calibration using phase referencing

    NASA Astrophysics Data System (ADS)

    Asaki, Yoshiharu; Matsushita, Satoki; Fomalont, Edward B.; Corder, Stuartt A.; Nyman, Lars-Åke; Dent, William R. F.; Philips, Neil M.; Hirota, Akihiko; Takahashi, Satoko; Vila-Vilaro, Baltasar; Nikolic, Bojan; Hunter, Todd R.; Remijan, Anthony; Vlahakis, Catherine

    2016-08-01

    The Atacama Large Millimeter/submillimeter Array (ALMA) is the world's largest millimeter/submillimeter telescope and provides unprecedented sensitivities and spatial resolutions. To achieve the highest imaging capabilities, interferometric phase calibration for the long baselines is one of the most important subjects: The longer the baselines, the worse the phase stability becomes because of turbulent motions of the Earth's atmosphere, especially, the water vapor in the troposphere. To overcome this subject, ALMA adopts a phase correction scheme using a Water Vapor Radiometer (WVR) to estimate the amount of water vapor content along the antenna line of sight. An additional technique is phase referencing, in which a science target and a nearby calibrator are observed by turn by quickly changing the antenna pointing. We conducted feasibility studies of the hybrid technique with the WVR phase correction and the antenna Fast Switching (FS) phase referencing (WVR+FS phase correction) for the ALMA 16 km longest baselines in cases that (1) the same observing frequency both for a target and calibrator is used, and (2) higher and lower frequencies for a target and calibrator, respectively, with a typical switching cycle time of 20 s. It was found that the phase correction performance of the hybrid technique is promising where a nearby calibrator is located within roughly 3◦ from a science target, and that the phase correction with 20 s switching cycle time significantly improves the performance with the above separation angle criterion comparing to the 120 s switching cycle time. The currently trial phase calibration method shows the same performance independent of the observing frequencies. This result is especially important for the higher frequency observations because it becomes difficult to find a bright calibrator close to an arbitrary sky position. In the series of our experiments, it is also found that phase errors affecting the image quality come from not only

  6. 40 CFR 80.90 - Conventional gasoline baseline emissions determination.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false Conventional gasoline baseline... gasoline baseline emissions determination. (a) Annual average baseline values. For any facility of a refiner or importer of conventional gasoline, the annual average baseline values of the facility's exhaust...

  7. 40 CFR 80.90 - Conventional gasoline baseline emissions determination.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 16 2011-07-01 2011-07-01 false Conventional gasoline baseline... gasoline baseline emissions determination. (a) Annual average baseline values. For any facility of a refiner or importer of conventional gasoline, the annual average baseline values of the facility's exhaust...

  8. 40 CFR 80.90 - Conventional gasoline baseline emissions determination.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 17 2012-07-01 2012-07-01 false Conventional gasoline baseline... gasoline baseline emissions determination. (a) Annual average baseline values. For any facility of a refiner or importer of conventional gasoline, the annual average baseline values of the facility's exhaust...

  9. 40 CFR 80.90 - Conventional gasoline baseline emissions determination.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 17 2013-07-01 2013-07-01 false Conventional gasoline baseline... gasoline baseline emissions determination. (a) Annual average baseline values. For any facility of a refiner or importer of conventional gasoline, the annual average baseline values of the facility's exhaust...

  10. 40 CFR 80.90 - Conventional gasoline baseline emissions determination.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 17 2014-07-01 2014-07-01 false Conventional gasoline baseline... gasoline baseline emissions determination. (a) Annual average baseline values. For any facility of a refiner or importer of conventional gasoline, the annual average baseline values of the facility's exhaust...

  11. On baseline corrections and uncertainty in response spectrafor baseline variations commonly encountered in digital accelerograph records

    USGS Publications Warehouse

    Akkar, Sinan; Boore, David M.

    2009-01-01

    Most digital accelerograph recordings are plagued by long-period drifts, best seen in the velocity and displacement time series obtained from integration of the acceleration time series. These drifts often result in velocity values that are nonzero near the end of the record. This is clearly unphysical and can lead to inaccurate estimates of peak ground displacement and long-period spectral response. The source of the long-period noise seems to be variations in the acceleration baseline in many cases. These variations could be due to true ground motion (tilting and rotation, as well as local permanent ground deformation), instrumental effects, or analog-to-digital conversion. Very often the trends in velocity are well approximated by a linear trend after the strong shaking subsides. The linearity of the trend in velocity implies that no variations in the baseline could have occurred after the onset of linearity in the velocity time series. This observation, combined with the lack of any trends in the pre-event motion, allows us to compute the time interval in which any baseline variations could occur. We then use several models of the variations in a Monte Carlo procedure to derive a suite of baseline-corrected accelerations for each noise model using records from the 1999 Chi-Chi earthquake and several earthquakes in Turkey. Comparisons of the mean values of the peak ground displacements, spectral displacements, and residual displacements computed from these corrected accelerations for the different noise models can be used as a guide to the accuracy of the baseline corrections. For many of the records considered here the mean values are similar for each noise model, giving confidence in the estimation of the mean values. The dispersion of the ground-motion measures increases with period and is noise-model dependent. The dispersion of inelastic spectra is greater than the elastic spectra at short periods but approaches that of the elastic spectra at longer periods

  12. Physiological and Performance Measures for Baseline Concussion Assessment.

    PubMed

    Dobney, Danielle M; Thomas, Scott G; Taha, Tim; Keightley, Michelle

    2017-05-17

    Baseline testing is a common strategy for concussion assessment and management. Research continues to evaluate novel measures for potential to improve baseline testing methods. The primary objective was to; 1) determine the feasibility of including physiological, neuromuscular and mood measures as part of baseline concussion testing protocol, 2) describe typical values in a varsity athlete sample, and 3) estimate the influence of concussion history on these baseline measures. Prospective observational study. University Athletic Therapy Clinic. 100 varsity athletes. Frequency and domain measures of heart rate variability (HRV), blood pressure (BP), grip strength, Profile of Mood States and the Sport Concussion Assessment Tool-2. Physiological, neuromuscular performance and mood measures were feasible at baseline. Participants with a history of two or more previous concussions displayed significantly higher diastolic blood pressure. Females reported higher total mood disturbance compared to males. Physiological and neuromuscular performance measures are safe and feasible as baseline concussion assessment outcomes. History of concussion may have an influence on diastolic blood pressure.

  13. 75 FR 66748 - Notice of Baseline Filings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-29

    ...- 000] Notice of Baseline Filings October 22, 2010. ONEOK Gas Transportation, L.L.C Docket No. PR11-68... above submitted a revised baseline filing of their Statement of Operating Conditions for services...

  14. Salud Mesoamérica 2015 Initiative: design, implementation, and baseline findings.

    PubMed

    Mokdad, Ali H; Colson, Katherine Ellicott; Zúñiga-Brenes, Paola; Ríos-Zertuche, Diego; Palmisano, Erin B; Alfaro-Porras, Eyleen; Anderson, Brent W; Borgo, Marco; Desai, Sima; Gagnier, Marielle C; Gillespie, Catherine W; Giron, Sandra L; Haakenstad, Annie; Romero, Sonia López; Mateus, Julio; McKay, Abigail; Mokdad, Ali A; Murphy, Tasha; Naghavi, Paria; Nelson, Jennifer; Orozco, Miguel; Ranganathan, Dharani; Salvatierra, Benito; Schaefer, Alexandra; Usmanova, Gulnoza; Varela, Alejandro; Wilson, Shelley; Wulf, Sarah; Hernandez, Bernardo; Lozano, Rafael; Iriarte, Emma; Regalia, Ferdinando

    2015-01-01

    Health has improved markedly in Mesoamerica, the region consisting of southern Mexico and Central America, over the past decade. Despite this progress, there remain substantial inequalities in health outcomes, access, and quality of medical care between and within countries. Poor, indigenous, and rural populations have considerably worse health indicators than national or regional averages. In an effort to address these health inequalities, the Salud Mesoamérica 2015 Initiative (SM2015), a results-based financing initiative, was established. For each of the eight participating countries, health targets were set to measure the progress of improvements in maternal and child health produced by the Initiative. To establish a baseline, we conducted censuses of 90,000 households, completed 20,225 household interviews, and surveyed 479 health facilities in the poorest areas of Mesoamerica. Pairing health facility and household surveys allows us to link barriers to care and health outcomes with health system infrastructure components and quality of health services. Indicators varied significantly within and between countries. Anemia was most prevalent in Panama and least prevalent in Honduras. Anemia varied by age, with the highest levels observed among children aged 0 to 11 months in all settings. Belize had the highest proportion of institutional deliveries (99%), while Guatemala had the lowest (24%). The proportion of women with four antenatal care visits with a skilled attendant was highest in El Salvador (90%) and the lowest in Guatemala (20%). Availability of contraceptives also varied. The availability of condoms ranged from 83% in Nicaragua to 97% in Honduras. Oral contraceptive pills and injectable contraceptives were available in just 75% of facilities in Panama. IUDs were observed in only 21.5% of facilities surveyed in El Salvador. These data provide a baseline of much-needed information for evidence-based action on health throughout Mesoamerica. Our baseline

  15. 2016 Annual Technology Baseline (ATB) - Webinar Presentation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cole, Wesley; Kurup, Parthiv; Hand, Maureen

    2016-09-13

    This deck was presented for the 2016 Annual Technology Baseline Webinar. The presentation describes the Annual Technology Baseline, which is a compilation of current and future cost and performance data for electricity generation technologies.

  16. Deadlines at work and sleep quality. Cross-sectional and longitudinal findings among Danish knowledge workers.

    PubMed

    Rugulies, Reiner; Martin, Marie H T; Garde, Anne Helene; Persson, Roger; Albertsen, Karen

    2012-03-01

    Exposure to deadlines at work is increasing in several countries and may affect health. We aimed to investigate cross-sectional and longitudinal associations between frequency of difficult deadlines at work and sleep quality. Study participants were knowledge workers, drawn from a representative sample of Danish employees who responded to a baseline questionnaire in 2006 (n = 363) and a follow-up questionnaire in 2007 (n = 302). Frequency of difficult deadlines was measured by self-report and categorized into low, intermediate, and high. Sleep quality was measured with a Total Sleep Quality Score and two indexes (Awakening Index and Disturbed Sleep Index) derived from the Karolinska Sleep Questionnaire. Analyses on the association between frequency of deadlines and sleep quality scores were conducted with multiple linear regression models, adjusted for potential confounders. In addition, we used multiple logistic regression models to analyze whether frequency of deadlines at baseline predicted caseness of sleep problems at follow-up among participants free of sleep problems at baseline. Frequent deadlines were cross-sectionally and longitudinally associated with poorer sleep quality on all three sleep quality measures. Associations in the longitudinal analyses were greatly attenuated when we adjusted for baseline sleep quality. The logistic regression analyses showed that frequent deadlines at baseline were associated with elevated odds ratios for caseness of sleep problems at follow-up, however, confidence intervals were wide in these analyses. Frequent deadlines at work were associated with poorer sleep quality among Danish knowledge workers. We recommend investigating the relation between deadlines and health endpoints in large-scale epidemiologic studies. Copyright © 2011 Wiley Periodicals, Inc.

  17. Salton Sea sampling program: baseline studies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tullis, R.E.; Carter, J.L.; Langlois, G.W.

    1981-04-13

    Baseline data are provided on three species of fish from the Salton Sea, California. The fishes considered were the orange mouth corvina (Cynoscion xanthulus), gulf croaker (Bairdiella icistius) and sargo (Anisotremus davidsonii). Morphometric and meristic data are presented as a baseline to aid in the evaluation of any physiological stress the fish may experience as a result of geothermal development. Analyses were made on muscle, liver, and bone of the fishes sampled to provide baseline data on elemental tissue burdens. The elements measured were: As, Br, Ca, Cu, Fe, Ga, K, Mn, Mi, Pb, Rb, Se, Sr, Zn, and Zr.more » These data are important if an environmentally sound progression of geothermal power production is to occur at the Salton Sea.« less

  18. Air traffic control system baseline methodology guide.

    DOT National Transportation Integrated Search

    1999-06-01

    The Air Traffic Control System Baseline Methodology Guide serves as a reference in the design and conduct of baseline studies. : Engineering research psychologists are the intended audience for the Methodology Guide, which focuses primarily on techni...

  19. TWRS technical baseline database manager definition document

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Acree, C.D.

    1997-08-13

    This document serves as a guide for using the TWRS Technical Baseline Database Management Systems Engineering (SE) support tool in performing SE activities for the Tank Waste Remediation System (TWRS). This document will provide a consistent interpretation of the relationships between the TWRS Technical Baseline Database Management software and the present TWRS SE practices. The Database Manager currently utilized is the RDD-1000 System manufactured by the Ascent Logic Corporation. In other documents, the term RDD-1000 may be used interchangeably with TWRS Technical Baseline Database Manager.

  20. First GPS baseline results from the North Andes

    NASA Technical Reports Server (NTRS)

    Kellogg, James N.; Freymueller, Jeffrey T.; Dixon, Timothy H.; Neilan, Ruth E.; Ropain, Clemente

    1990-01-01

    The CASA Uno GPS experiment (January-February 1988) has provided the first epoch baseline measurements for the study of plate motions and crustal deformation in and around the North Andes. Two dimensional horizontal baseline repeatabilities are as good as 5 parts in 10 to the 8th for short baselines (100-1000 km), and better than 3 parts in 10 to the 8th for long baselines (greater than 1000 km). Vertical repeatabilities are typically 4-6 cm, with a weak dependence on baseline length. The expected rate of plate convergence across the Colombia Trench is 6-8cm/yr, which should be detectable by the repeat experiment planned for 1991. Expected deformation rates within the North Andes are of the order of 1 cm/yr, which may be detectable with the 1991 experiment.

  1. Efficient algorithm for baseline wander and powerline noise removal from ECG signals based on discrete Fourier series.

    PubMed

    Bahaz, Mohamed; Benzid, Redha

    2018-03-01

    Electrocardiogram (ECG) signals are often contaminated with artefacts and noises which can lead to incorrect diagnosis when they are visually inspected by cardiologists. In this paper, the well-known discrete Fourier series (DFS) is re-explored and an efficient DFS-based method is proposed to reduce contribution of both baseline wander (BW) and powerline interference (PLI) noises in ECG records. In the first step, the determination of the exact number of low frequency harmonics contributing in BW is achieved. Next, the baseline drift is estimated by the sum of all associated Fourier sinusoids components. Then, the baseline shift is discarded efficiently by a subtraction of its approximated version from the original biased ECG signal. Concerning the PLI, the subtraction of the contributing harmonics calculated in the same manner reduces efficiently such type of noise. In addition of visual quality results, the proposed algorithm shows superior performance in terms of higher signal-to-noise ratio and smaller mean square error when faced to the DCT-based algorithm.

  2. Life Support Baseline Values and Assumptions Document

    NASA Technical Reports Server (NTRS)

    Anderson, Molly S.; Ewert, Michael K.; Keener, John F.

    2018-01-01

    The Baseline Values and Assumptions Document (BVAD) provides analysts, modelers, and other life support researchers with a common set of values and assumptions which can be used as a baseline in their studies. This baseline, in turn, provides a common point of origin from which many studies in the community may depart, making research results easier to compare and providing researchers with reasonable values to assume for areas outside their experience. This document identifies many specific physical quantities that define life support systems, serving as a general reference for spacecraft life support system technology developers.

  3. Life Support Baseline Values and Assumptions Document

    NASA Technical Reports Server (NTRS)

    Anderson, Molly S.; Ewert, Michael K.; Keener, John F.; Wagner, Sandra A.

    2015-01-01

    The Baseline Values and Assumptions Document (BVAD) provides analysts, modelers, and other life support researchers with a common set of values and assumptions which can be used as a baseline in their studies. This baseline, in turn, provides a common point of origin from which many studies in the community may depart, making research results easier to compare and providing researchers with reasonable values to assume for areas outside their experience. With the ability to accurately compare different technologies' performance for the same function, managers will be able to make better decisions regarding technology development.

  4. 40 CFR 80.850 - How is the compliance baseline determined?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false How is the compliance baseline... Requirements § 80.850 How is the compliance baseline determined? (a) The compliance baseline to which annual... equation: ER29mr01.001 Where: TCBase = Compliance baseline toxics value. TBase = Baseline toxics value for...

  5. Mapping Forest Height in Gabon Using UAVSAR Multi-Baseline Polarimetric SAR Interferometry and Lidar Fusion

    NASA Astrophysics Data System (ADS)

    Simard, M.; Denbina, M. W.

    2017-12-01

    Using data collected by NASA's Uninhabited Aerial Vehicle Synthetic Aperture Radar (UAVSAR) and Land, Vegetation, and Ice Sensor (LVIS) lidar, we have estimated forest canopy height for a number of study areas in the country of Gabon using a new machine learning data fusion approach. Using multi-baseline polarimetric synthetic aperture radar interferometry (PolInSAR) data collected by UAVSAR, forest heights can be estimated using the random volume over ground model. In the case of multi-baseline UAVSAR data consisting of many repeat passes with spatially separated flight tracks, we can estimate different forest height values for each different image pair, or baseline. In order to choose the best forest height estimate for each pixel, the baselines must be selected or ranked, taking care to avoid baselines with unsuitable spatial separation, or severe temporal decorrelation effects. The current baseline selection algorithms in the literature use basic quality metrics derived from the PolInSAR data which are not necessarily indicative of the true height accuracy in all cases. We have developed a new data fusion technique which treats PolInSAR baseline selection as a supervised classification problem, where the classifier is trained using a sparse sampling of lidar data within the PolInSAR coverage area. The classifier uses a large variety of PolInSAR-derived features as input, including radar backscatter as well as features based on the PolInSAR coherence region shape and the PolInSAR complex coherences. The resulting data fusion method produces forest height estimates which are more accurate than a purely radar-based approach, while having a larger coverage area than the input lidar training data, combining some of the strengths of each sensor. The technique demonstrates the strong potential for forest canopy height and above-ground biomass mapping using fusion of PolInSAR with data from future spaceborne lidar missions such as the upcoming Global Ecosystems

  6. Questa baseline and pre-mining ground-water quality investigation. 3. Historical ground-water quality for the Red River Valley, New Mexico

    USGS Publications Warehouse

    LoVetere, Sara H.; Nordstrom, D. Kirk; Maest, Ann S.; Naus, Cheryl A.

    2003-01-01

    Historical ground-water quality data for 100 wells in the Red River Valley between the U.S. Geological Survey streamflow-gaging station (08265000), near Questa, and Placer Creek east of the town of Red River, New Mexico, were compiled and reviewed. The tabulation included 608 water-quality records from 23 sources entered into an electronic database. Groundwater quality data were first collected at the Red River wastewater-treatment facility in 1982. Most analyses, however, were obtained between 1994 and 2002, even though the first wells were developed in 1962. The data were evaluated by considering (a) temporal consistency, (b) quality of sampling methods, (c) charge imbalance, and (d) replicate analyses. Analyses that qualified on the basis of these criteria were modeled to obtain saturation indices for gypsum, calcite, fluorite, gibbsite, manganite, and rhodocrosite. Plots created from the data illustrate that water chemistry in the Red River Valley is predominantly controlled by calcite dissolution, congruent gypsum dissolution, and pyrite oxidation.

  7. Effects of adjunctive N-acetylcysteine on depressive symptoms: Modulation by baseline high-sensitivity C-reactive protein.

    PubMed

    Porcu, Mauro; Urbano, Mariana Ragassi; Verri, Waldiceu A; Barbosa, Decio Sabbatini; Baracat, Marcela; Vargas, Heber Odebrecht; Machado, Regina Célia Bueno Rezende; Pescim, Rodrigo Rossetto; Nunes, Sandra Odebrecht Vargas

    2018-05-01

    Outcomes in a RCTs of 12 weeks of theclinical efficacy of N-acetylcysteine (NAC) as an adjunctive treatment on depression and anxiety symptoms and its effects on high-sensitivity C-reactive protein (hs-CRP) levels. A wide array of measures were made. The 17-item version of the Hamilton Depression Rating Scale (HDRS17); the Hamilton Anxiety Rating Scale (HAM-A); Sheehan Disability Scale; Quality of Life; Clinical Global Impression (CGI); anthropometrics measures; and vital signs and biochemical laboratory. There were no significant differences among the groups regarding demographic, clinical features, use of medication, metabolic syndrome and comorbidities. From baseline to week 12, individuals receiving NAC, versus placebo, had a statistically significant reduction in depressive symptoms on HDRS 17 (p < 0.01) and anxiety symptoms on HAM-A (p = 0.04), but only for individuals with levels of hs-CRP > 3 mg/L at baseline. Individuals receiving NAC with baseline levels of hs-CRP > 3 mg/L, had more significant reduction in uric acid levels compared to individuals with baseline levels of hs-CRP ≤ 3 mg/L on week 12. Participants receiving placebogained significantly more weight during the 12 weeks for baseline levels of hs-CRP ≤ 3 mg/L and hs-CRP > 3 mg/L, and individuals receiving NAC in both groups did not have significant weight change during the 12 weeks. No individuals were withdrawn from the study because of adverse event. NAC group exhibited significantly greater reduction on hs-CRP levels than placebo group from baseline to week 12. clinicaltrials.gov Identifier; NCT02252341. Copyright © 2018 Elsevier B.V. All rights reserved.

  8. Compositional diversity in peridotites as result of a multi-process history: The Pacific-derived Santa Elena ophiolite, northwest Costa Rica

    NASA Astrophysics Data System (ADS)

    Escuder-Viruete, Javier; Baumgartner, Peter O.; Castillo-Carrión, Mercedes

    2015-08-01

    The Santa Elena ophiolite (SEO) is an ultramafic nappe of more than 270 km2 overlying a tectonic serpentinite-matrix mélange in northwest Costa Rica. It is mainly composed of Cpx-rich and Cpx-poor harzburgites (~ 2.5 km-thick), with minor lherzolite, dunite and chromitite, as well as intrusive mafic sills and subvertical dikes, which coalesce into an upper Isla Negritos gabbroic sill complex. Minerals and whole-rock features of the Cpx-rich and Cpx-poor harzburgites share features of the abyssal and supra-subduction zone (SSZ) peridotites, respectively. To explain these characteristics two-stages of melting and refertilization processes are required. By means of trace element modeling, the composition of Cpx-rich harzburgites may be reproduced by up to ~ 5-10% melting of a primitive mantle source, and the composition of Cpx-poor harzburgites and dunites by ~ 15-18% melting of an already depleted mantle. Therefore, the Cpx-rich harzburgites can be interpreted as product of first-stage melting and low-degrees of melt-rock interaction in a mid-ocean ridge environment, and the Cpx-poor harzburgites and dunites as the product of second-stage melting and refertilization in a SSZ setting. The mafic sills and the Isla Negrito gabbros are genetically related and can be explained as crystallization from the liquids that were extracted from the lower SSZ mantle levels and emplaced at shallow conditions. The Murciélagos Island basalts are not directly related to the ultramafic and mafic rocks of the SEO. Their E-MORB-like composition is similar to most of the CLIP mafic lavas and suggests a common Caribbean plume-related source. The SEO represents a fragment of Pacific-derived, SSZ oceanic lithosphere emplaced onto the southern North America margin during the late Cretaceous. Because of the predominance of rollback-induced extension during its history, only a limited amount of crustal rocks were formed and preserved in the SEO.

  9. The administrator's quest for quality.

    PubMed

    Ross, A

    1988-01-01

    Times are tough and will become even tougher. Retrenchment issues will be foremost in many operational settings. Failure to understand baseline quality standards will make it extremely difficult to know where to cut and how to regroup without adversely affecting patient attitudes and service. Practice patterns are changing rapidly and the astute administrator needs to be prepared to participate freely in decisions affecting quality, service and costs.

  10. 75 FR 74706 - Notice of Baseline Filings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-01

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Notice of Baseline Filings November 24, 2010. Centana Intrastate Pipeline, LLC. Docket No. PR10-84-001. Centana Intrastate Pipeline, LLC... applicants listed above submitted a revised baseline filing of their Statement of Operating Conditions for...

  11. Atmospheric phase characteristics of the ALMA long baseline

    NASA Astrophysics Data System (ADS)

    Matsushita, Satoki; Asaki, Yoshiharu; Fomalont, Edward B.; Barkats, Denis; Corder, Stuartt A.; Hills, Richard E.; Kawabe, Ryohei; Maud, Luke T.; Morita, Koh-Ichiro; Nikolic, Bojan; Tilanus, Remo P. J.; Vlahakis, Catherine

    2016-07-01

    Atacama Large Millimeter/submillimeter Array (ALMA) is the world's largest millimeter/ submillimeter (mm / Submm) interferometer. Along with science observations, ALMA has performed several long baseline campaigns in the last 6 years to characterize and optimize its long baseline capabilities. To achieve full long baseline capability of ALMA, it is important to understand the characteristics of atmospheric phase fluctuation at long baselines, since it is believed to be the main cause of mm/submm image degradation. For the first time, we present detailed properties of atmospheric phase fluctuation at mm/submm wavelength from baselines up to 15 km in length. Atmospheric phase fluctuation increases as a function of baseline length with a power-law slope close to 0.6, and many of the data display a shallower slope (02.-03) at baseline length greater than about 15 km. Some of the data, on the other hand, show a single slope up to the maximum baseline length of around 15 km. The phase correction method based on water vapor radiometers (WVRs) works well, especially for cases with precipitable water vapor (PWV) greater than 1 mm, typically yielding a 50% decrease or more in the degree of phase fluctuation. However, signicant amount of atmospheric phase fluctuation still remains after the WVR phase correction: about 200 micron in rms excess path length (rms phase fluctuation in unit of length) even at PWV less than 1 mm. This result suggests the existence of other non-water-vapor sources of phase fluctuation. and emphasizes the need for additional phase correction methods, such as band-to-band and/or fast switching.

  12. 75 FR 49918 - Notice of Baseline Filings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-16

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Notice of Baseline Filings August 6... submitted their baseline filing of its Statement of Operating Conditions for services provided under section... an original and 14 copies of the protest or intervention to the Federal Energy Regulatory Commission...

  13. Baseline assessment of physical characteristics, aquatic biota, and selected water-quality properties at the reach and mesohabitat scale for three stream reaches in the Big Cypress Basin, northeastern Texas, 2010-11

    USGS Publications Warehouse

    Braun, Christopher L.; Moring, James B.

    2013-01-01

    The U.S. Geological Survey (USGS), in cooperation with the Northeast Texas Municipal Water District and the Texas Commission on Environmental Quality, did a baseline assessment in 2010-11 of physical characteristics and selected aquatic biota (fish and mussels) collected at the mesohabitat scale for three stream reaches in the Big Cypress Basin in northeastern Texas for which environmental flows have been prescribed. Mesohabitats are visually distinct units of habitat within the stream with unique depth, velocity, slope, substrate, and cover. Mesohabitats in reaches of Big Cypress, Black Cypress, and Little Cypress Bayous were evaluated to gain an understanding of how fish communities and mussel populations varied by habitat. Selected water-quality properties were also measured in isolated pools in Black Cypress and Little Cypress. All of the data were collected in the context of the prescribed environmental flows. The information acquired during the study will support the long-term monitoring of biota in relation to the prescribed environmental flows.

  14. The Quality of Medication Use in Older Adults: Methods of a Longitudinal Study

    PubMed Central

    Roth, Mary T.; Moore, Charity G.; Ivey, Jena L.; Esserman, Denise A.; Campbell, William H.; Weinberger, Morris

    2009-01-01

    Background The quality of medication use in older adults is a recurring problem of substantial concern. Efforts to both measure and improve the quality of medication use often define quality too narrowly and fall short of addressing the complexity of an older adult's medication regimen. Objective In an effort to more comprehensively define the quality of medication use in older adults, we conducted a prospective cohort study to: 1) describe the quality of medication use in community-residing older adults at baseline, examining differences between Whites and African Americans; 2) examine the effect of race on medication-related problems[mtr1], and 3) assess the change in quality medication use between Whites and African Americans over time. This paper presents the research design and methods of this longitudinal study. Methods We interviewed 100 White and 100 African-American community-residing older adults three times over one year (baseline, 6, and 12 months). We oversampled African Americans so that we could estimate racial differences in the quality of medication use. We collected information on the quality of medication use, relying on a clinical pharmacist's assessment of quality and the Assessing Care of Vulnerable Elders (ACOVE) quality indicators. We also collected data on demographic characteristics, health literacy, functional status, and participant-reported drug therapy concerns. Results Two hundred older adults were enrolled into the study and completed a baseline visit. Of the 200, 92% completed the 6-month visit (n=183) and 88% completed the 12-month visit (n=176). We present baseline demographic characteristics for the 200 older adults enrolled in the study. Conclusion This longitudinal study is an initial step toward developing more comprehensive, patient-centered measures and interventions to improve the quality of medication use in older adults. PMID:19028378

  15. A rapid response air quality analysis system for use in projects having stringent quality assurance requirements

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bowman, A.W.

    1990-04-01

    This paper describes an approach to solve air quality problems which frequently occur during iterations of the baseline change process. From a schedule standpoint, it is desirable to perform this evaluation in as short a time as possible while budgetary pressures limit the size of the staff available to do the work. Without a method in place to deal with baseline change proposal requests the environment analysts may not be able to produce the analysis results in the time frame expected. Using a concept called the Rapid Response Air Quality Analysis System (RAAS), the problems of timing and cost becomemore » tractable. The system could be adapted to assess other atmospheric pathway impacts, e.g., acoustics or visibility. The air quality analysis system used to perform the EA analysis (EA) for the Salt Repository Project (part of the Civilian Radioactive Waste Management Program), and later to evaluate the consequences of proposed baseline changes, consists of three components: Emission source data files; Emission rates contained in spreadsheets; Impact assessment model codes. The spreadsheets contain user-written codes (macros) that calculate emission rates from (1) emission source data (e.g., numbers and locations of sources, detailed operating schedules, and source specifications including horsepower, load factor, and duty cycle); (2) emission factors such as those published by the U.S. Environmental Protection Agency, and (3) control efficiencies.« less

  16. Owning the program technical baseline for future space systems acquisition: program technical baseline tracking tool

    NASA Astrophysics Data System (ADS)

    Nguyen, Tien M.; Guillen, Andy T.; Hant, James J.; Kizer, Justin R.; Min, Inki A.; Siedlak, Dennis J. L.; Yoh, James

    2017-05-01

    The U.S. Air Force (USAF) has recognized the needs for owning the program and technical knowledge within the Air Force concerning the systems being acquired to ensure success. This paper extends the previous work done by the authors [1-2] on the "Resilient Program Technical Baseline Framework for Future Space Systems" and "Portfolio Decision Support Tool (PDST)" to the development and implementation of the Program and Technical Baseline (PTB) Tracking Tool (PTBTL) for the DOD acquisition life cycle. The paper describes the "simplified" PTB tracking model with a focus on the preaward phases and discusses how to implement this model in PDST.

  17. Intrafractional baseline drift during free breathing breast cancer radiation therapy.

    PubMed

    Jensen, Christer Andre; Acosta Roa, Ana María; Lund, Jo-Åsmund; Frengen, Jomar

    2017-06-01

    Intrafraction motion in breast cancer radiation therapy (BCRT) has not yet been thoroughly described in the literature. It has been observed that baseline drift occurs as part of the intrafraction motion. This study aims to measure baseline drift and its incidence in free-breathing BCRT patients using an in-house developed laser system for tracking the position of the sternum. Baseline drift was monitored in 20 right-sided breast cancer patients receiving free breathing 3D-conformal RT by using an in-house developed laser system which measures one-dimensional distance in the AP direction. A total of 357 patient respiratory traces from treatment sessions were logged and analysed. Baseline drift was compared to patient positioning error measured from in-field portal imaging. The mean overall baseline drift at end of treatment sessions was -1.3 mm for the patient population. Relatively small baseline drift was observed during the first fraction; however it was clearly detected already at the second fraction. Over 90% of the baseline drift occurs during the first 3 min of each treatment session. The baseline drift rate for the population was -0.5 ± 0.2 mm/min in the posterior direction the first minute after localization. Only 4% of the treatment sessions had a 5 mm or larger baseline drift at 5 min, all towards the posterior direction. Mean baseline drift in the posterior direction in free breathing BCRT was observed in 18 of 20 patients over all treatment sessions. This study shows that there is a substantial baseline drift in free breathing BCRT patients. No clear baseline drift was observed during the first treatment session; however, baseline drift was markedly present at the rest of the sessions. Intrafraction motion due to baseline drift should be accounted for in margin calculations.

  18. Diet Quality Is Linked to Insulin Resistance among Adults in China.

    PubMed

    Wang, Zhihong; Adair, Linda S; Cai, Jianwen; Gordon-Larsen, Penny; Siega-Riz, Anna Maria; Zhang, Bing; Popkin, Barry M

    2017-11-01

    Background: Little is known about the impact of Chinese diet quality changes on diabetes-related markers. Objective: The present study examined the association of changes in overall diet quality with various biomarkers of diabetes among adults in China. Methods: The current analysis used longitudinal diet data from 1991 to 2006 and fasting blood samples from 2009 for 4734 adults aged 18-65 y from the China Health and Nutrition Survey. Dietary intake was assessed by using 3 consecutive 24-h recalls and household food weighing. The tailored Alternative Healthy Eating Index (tAHEI) was adapted from the 2010 Harvard Alternative Healthy Eating Index to measure overall diet quality. We categorized baseline tAHEI scores into tertiles and annual changes in the scores into 5 levels (high decrease, low decrease, maintain, low increase, and high increase). We performed mixed-effects regressions to assess the associations between baseline scores and changes in the tAHEI scores and diabetes or insulin markers. Results: Adults with high baseline tAHEI scores tended to be male, older, of lower socioeconomic status, and with higher physical activity levels. After adjustment for all of the covariates, insulin and homeostasis model assessment of insulin resistance (HOMA-IR) values were 5.1% (95% CI: -0.100, -0.002) and 5.7% (95% CI: -0.113, -0.001) lower, respectively, for adults with high compared with low baseline tAHEI scores and 8.6% (95% CI: -0.155, -0.017) and 9.8% (95% CI: -0.177, -0.018) lower, respectively, for adults with a high increase in score compared with the "maintain" category. Null associations were observed between baseline scores and changes in the scores and fasting blood glucose, glycated hemoglobin (HbA1c), and diabetes prevalence. Conclusions: Baseline and changes in diet quality were independently associated with lower HOMA-IR and plasma insulin but not with fasting blood glucose and HbA1c in Chinese adults. Prospective studies on overall diet quality in

  19. Extracting Baseline Electricity Usage Using Gradient Tree Boosting

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kim, Taehoon; Lee, Dongeun; Choi, Jaesik

    To understand how specific interventions affect a process observed over time, we need to control for the other factors that influence outcomes. Such a model that captures all factors other than the one of interest is generally known as a baseline. In our study of how different pricing schemes affect residential electricity consumption, the baseline would need to capture the impact of outdoor temperature along with many other factors. In this work, we examine a number of different data mining techniques and demonstrate Gradient Tree Boosting (GTB) to be an effective method to build the baseline. We train GTB onmore » data prior to the introduction of new pricing schemes, and apply the known temperature following the introduction of new pricing schemes to predict electricity usage with the expected temperature correction. Our experiments and analyses show that the baseline models generated by GTB capture the core characteristics over the two years with the new pricing schemes. In contrast to the majority of regression based techniques which fail to capture the lag between the peak of daily temperature and the peak of electricity usage, the GTB generated baselines are able to correctly capture the delay between the temperature peak and the electricity peak. Furthermore, subtracting this temperature-adjusted baseline from the observed electricity usage, we find that the resulting values are more amenable to interpretation, which demonstrates that the temperature-adjusted baseline is indeed effective.« less

  20. Student quality-of-life declines during third year surgical clerkship.

    PubMed

    Goldin, Steven B; Wahi, Monika M; Farooq, Osman S; Borgman, Heather A; Carpenter, Heather L; Wiegand, Lucas R; Nixon, Lois L; Paidas, Charles; Rosemurgy, Alexander S; Karl, Richard C

    2007-11-01

    Choosing surgery as a career is declining among U.S. medical students. The 8-wk third year surgery clerkship at our institution can be an intense learning experience, and we hypothesized that during this clerkship medical student quality-of-life would drop significantly from baseline, and that this drop would be greater among certain subgroups, such as women students not interested in pursuing a surgical career, and those who place a high value on a controllable lifestyle. At clerkship orientation (baseline), students were asked to complete a survey that measured quality-of-life on an 84-point scale, and depression on a 40-point scale. The quality-of-life scale was composed of select questions from the Medical Outcomes Study, and the Harvard Department of Psychiatry/NDSD brief screening instrument was used to measure depression. Students were also asked the typical number of hours they slept per night. Demographics, attitude toward a controllable lifestyle, and top three specialties of interest were also gathered at baseline. On week 6 of the clerkship, students were surveyed on the same quality-of -life and depression scales, and asked average hours of sleep per night for the previous week. From June 2005 through December 2006, 143 of 177 (81%) students agreed to participate, and after exclusions for missing data, 137 students were included in the analysis. Sixty-nine students were women (51%), and the average age was 25.8 (sd 2.6). Mean quality-of-life at baseline was 57.0 (sd 11.3) and at week 6 was 50.4 (sd 10.1) representing a statistically significant average decline of 6.6 points (P < 0.0001). Mean depression at baseline was 14.4 (sd 3.8) and at week 6 was 15.1 (sd 3.6), representing a small but significant average decline of 0.7 points (P = 0.0155). Mean sleep at baseline was 6.3 h/night (sd 0.9) and at week 6 was 5.7 h/night (sd 1.2), representing a statistically significant average decline of 0.6 h/night (P < 0.0001). Declines were similar on all outcomes

  1. Patient-reported outcomes in the ProtecT randomized trial of clinically localized prostate cancer treatments: study design, and baseline urinary, bowel and sexual function and quality of life.

    PubMed

    Lane, Athene; Metcalfe, Chris; Young, Grace J; Peters, Tim J; Blazeby, Jane; Avery, Kerry N L; Dedman, Daniel; Down, Liz; Mason, Malcolm D; Neal, David E; Hamdy, Freddie C; Donovan, Jenny L

    2016-12-01

    To present the baseline patient-reported outcome measures (PROMs) in the Prostate Testing for Cancer and Treatment (ProtecT) randomized trial comparing active monitoring, radical prostatectomy and external-beam conformal radiotherapy for localized prostate cancer and to compare results with other populations. A total of 1643 randomized men, aged 50-69 years and diagnosed with clinically localized disease identified by prostate-specific antigen (PSA) testing, in nine UK cities in the period 1999-2009 were included. Validated PROMs for disease-specific (urinary, bowel and sexual function) and condition-specific impact on quality of life (Expanded Prostate Index Composite [EPIC], 2005 onwards; International Consultation on Incontinence Questionnaire-Urinary Incontinence [ICIQ-UI], 2001 onwards; the International Continence Society short-form male survey [ICSmaleSF]; anxiety and depression (Hospital Anxiety and Depression Scale [HADS]), generic mental and physical health (12-item short-form health survey [SF-12]; EuroQol quality-of-life survey, the EQ-5D-3L) were assessed at prostate biopsy clinics before randomization. Descriptive statistics are presented by treatment allocation and by men's age at biopsy and PSA testing time points for selected measures. A total of 1438 participants completed biopsy questionnaires (88%) and 77-88% of these were analysed for individual PROMs. Fewer than 1% of participants were using pads daily (5/754). Storage lower urinary tract symptoms were frequent (e.g. nocturia 22%, 312/1423). Bowel symptoms were rare, except for loose stools (16%, 118/754). One third of participants reported erectile dysfunction (241/735) and for 16% (118/731) this was a moderate or large problem. Depression was infrequent (80/1399, 6%) but 20% of participants (278/1403) reported anxiety. Sexual function and bother were markedly worse in older men (65-70 years), whilst urinary bother and physical health were somewhat worse than in younger men (49-54 years, all

  2. Integrated Baseline Review (IBR) Handbook

    NASA Technical Reports Server (NTRS)

    2013-01-01

    An Integrated Baseline Review (IBR) is a review of a supplier?s Performance Measurement Baseline (PMB). It is conducted by Program/Project Managers and their technical staffs on contracts and in-house work requiring compliance with NASA Earned Value Management System (EVMS) policy as defined in program/project policy, NPR 7120.5, or in NASA Federal Acquisition Regulations. The IBR Handbook may also be of use to those responsible for preparing the Terms of Reference for internal project reviews. While risks may be identified and actions tracked as a result of the IBR, it is important to note that an IBR cannot be failed.

  3. 75 FR 47291 - Notice of Baseline Filings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-05

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Notice of Baseline Filings July 29, 2010. ONEOK Gas Storage, L.L.C Docket No. PR10-67-000. Atmos Energy--Kentucky/Mid-States Division Docket No... applicants listed above submitted their baseline filing of its Statement of Operating Conditions for services...

  4. Caregiver negative affect is a primary determinant of caregiver report of pediatric asthma quality of life.

    PubMed

    Price, Marcella R; Bratton, Donna L; Klinnert, Mary D

    2002-12-01

    Quality of life has increased in popularity as an outcome measure in health research. However, the measurement of quality of life has been questioned on methodologic grounds, as it often shows little association with objective measures of disease status. For this report we studied the determinants of pediatric asthma caregiver report of quality of life and its relationship to disease burden. Ninety-eight children who were admitted to a Pediatric Day Program for an asthma evaluation were enrolled in an outcome study. A complete set of medical records for the 2-year period before and after the admission was collected and systematically coded for health care utilization. Using the Pediatric Asthma Caregiver's Quality of Life Questionnaire, data were collected at baseline, discharge, and year after the admission. Caregiver negative affect (anxiety and depression), measured with the Brief Symptom Inventory, was also collected at baseline and discharge. Caregiver report of quality of life was unrelated to health care utilization at baseline but instead was significantly related to baseline caregiver negative affect. A significant relationship between health care utilization and quality of life was present at followup. The Emotional Function scale from the quality of life measure can account for most of the relationship between quality of life and negative affect. Caregiver affect may have a considerable influence on report of quality of life. Understanding the individual characteristics of the respondent is important when using a quality of life instrument as an outcome measure.

  5. Sustainability in the AAP Bronchiolitis Quality Improvement Project.

    PubMed

    Shadman, Kristin A; Ralston, Shawn L; Garber, Matthew D; Eickhoff, Jens; Mussman, Grant M; Walley, Susan C; Rice-Conboy, Elizabeth; Coller, Ryan J

    2017-11-01

    Adherence to American Academy of Pediatrics (AAP) bronchiolitis clinical practice guideline recommendations improved significantly through the AAP's multiinstitutional collaborative, the Bronchiolitis Quality Improvement Project (BQIP). We assessed sustainability of improvements at participating institutions for 1 year following completion of the collaborative. Twenty-one multidisciplinary hospital-based teams provided monthly data for key inpatient bronchiolitis measures during baseline and intervention bronchiolitis seasons. Nine sites provided data in the season following completion of the collaborative. Encounters included children younger than 24 months who were hospitalized for bronchiolitis without comorbid chronic illness, prematurity, or intensive care. Changes between baseline-, intervention-, and sustainability-season data were assessed using generalized linear mixed-effects models with site-specific random effects. Differences between hospital characteristics, baseline performance, and initial improvement between sites that did and did not participate in the sustainability season were compared. A total of 2275 discharges were reviewed, comprising 995 baseline, 877 intervention, and 403 sustainability- season encounters. Improvements in all key bronchiolitis quality measures achieved during the intervention season were maintained during the sustainability season, and orders for intermittent pulse oximetry increased from 40.6% (95% confidence interval [CI], 22.8-61.1) to 79.2% (95% CI, 58.0- 91.3). Sites that did and did not participate in the sustainability season had similar characteristics. BQIP participating sites maintained improvements in key bronchiolitis quality measures for 1 year following the project's completion. This approach, which provided an evidence-based best-practice toolkit while building the quality-improvement capacity of local interdisciplinary teams, may support performance gains that persist beyond the active phase of the

  6. Multi-baseline bootstrapping at the Navy precision optical interferometer

    NASA Astrophysics Data System (ADS)

    Armstrong, J. T.; Schmitt, H. R.; Mozurkewich, D.; Jorgensen, A. M.; Muterspaugh, M. W.; Baines, E. K.; Benson, J. A.; Zavala, Robert T.; Hutter, D. J.

    2014-07-01

    The Navy Precision Optical Interferometer (NPOI) was designed from the beginning to support baseline boot- strapping with equally-spaced array elements. The motivation was the desire to image the surfaces of resolved stars with the maximum resolution possible with a six-element array. Bootstrapping two baselines together to track fringes on a third baseline has been used at the NPOI for many years, but the capabilities of the fringe tracking software did not permit us to bootstrap three or more baselines together. Recently, both a new backend (VISION; Tennessee State Univ.) and new hardware and firmware (AZ Embedded Systems and New Mexico Tech, respectively) for the current hybrid backend have made multi-baseline bootstrapping possible.

  7. 76 FR 5797 - Notice of Baseline Filings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-02

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR10-114-001; Docket No. PR10-129-001; Docket No. PR10-131- 001; Docket No. PR10-68-002 Not Consolidated] Notice of Baseline... applicants listed above submitted a revised baseline filing of their Statement of Operating Conditions for...

  8. Short and Long Baseline Neutrino Experiments

    NASA Astrophysics Data System (ADS)

    Autiero, Dario

    2005-04-01

    These two lectures discuss the past and current neutrino oscillation experiments performed with man-made neutrino sources, like accelerators and nuclear reactors. The search for neutrino oscillations is a remarkable effort, which has been performed over three decades. It is therefore interesting to discuss the short and long baseline neutrino experiments in their historical context and to see how this line of research evolved up to the present generation of experiments, looking at what was learnt from past experiments and how this experience is used in the current ones. The first lecture focuses on the past generation of short baseline experiments (NOMAD and CHORUS) performed at CERN and ends with LSND and MINIBOONE. The second lecture discusses how after the CHOOZ and the atmospheric neutrino results the line of the long baseline experiments developed and presents in details the K2K and MINOS experiments and the CNGS program.

  9. Method and apparatus for reliable inter-antenna baseline determination

    NASA Technical Reports Server (NTRS)

    Wilson, John M. (Inventor)

    2001-01-01

    Disclosed is a method for inter-antenna baseline determination that uses an antenna configuration comprising a pair of relatively closely spaced antennas and other pairs of distant antennas. The closely spaced pair provides a short baseline having an integer ambiguity that may be searched exhaustively to identify the correct set of integers. This baseline is then used as a priori information to aid the determination of longer baselines that, once determined, may be used for accurate run time attitude determination.

  10. Diet quality of US adolescents during the transition to adulthood: changes and predictors.

    PubMed

    Lipsky, Leah M; Nansel, Tonja R; Haynie, Denise L; Liu, Danping; Li, Kaigang; Pratt, Charlotte A; Iannotti, Ronald J; Dempster, Katherine W; Simons-Morton, Bruce

    2017-06-01

    Background: Influences on diet quality during the transition from adolescence to adulthood are understudied. Objective: This study examined association of 3 diet-quality indicators-Healthy Eating Index-2010 (HEI), Whole Plant Foods Density (WPF), and Empty Calories (EC; the percentage of calories from discretionary solid fat, added sugar and alcohol)-with lifestyle behaviors, baseline weight status, and sociodemographic characteristics in US emerging adults. Design: Data come from the first 4 waves (annual assessments) of the NEXT Plus Study, a population-based cohort of 10th graders enrolled in 2010 ( n = 566). At each assessment, participants completed 3 nonconsecutive 24-h diet recalls, wore accelerometers for 7 d, and self-reported meal practices and sedentary behaviors. Self-reported sociodemographic characteristics were ascertained at baseline. Generalized estimating equations examined associations of time-varying diet quality with baseline weight status and sociodemographic characteristics and time-varying lifestyle behaviors. Results: Diet quality improved modestly from baseline (mean ± SE: HEI, 44.07 ± 0.53; WPF, 1.24 ± 0.04; and EC, 35.66 ± 0.55) to wave 4 for WPF (1.44 ± 0.05, P < 0.001) and EC (33.47 ± 0.52, P < 0.001), but not HEI (45.22 ± 0.60). In longitudinal analyses, higher HEI and lower EC scores were observed in Hispanic compared with white participants. Better diet quality was associated with greater moderate-to-vigorous physical activity, more frequent breakfast and family meals, less frequent fast food and meals during television viewing, and shorter durations of television viewing, gaming, and online social networking. Diet-quality indicators were not consistently associated with time-varying physical inactivity, baseline weight status, or sociodemographic characteristics. Conclusions: Diet quality of emerging adults in the US remained suboptimal, but some aspects improved marginally over the 4-y study period. Meal contexts and

  11. Intersections between immigration, language, identity, and emotions: a science teacher candidate's journey

    NASA Astrophysics Data System (ADS)

    Rivera Maulucci, Maria S.

    2008-04-01

    This study reports a subset of findings from a larger, ongoing study aimed at exploring interactions between teacher identity, learning, and classroom practices in a social justice teacher education program at a selective liberal arts college in New York. This case-study explores the journey of Elena, as an immigrant, a student, and a pre-service teacher candidate towards becoming a social justice educator. Elena reflects upon her school language experiences as an immigrant youth, her learning in a social justice teacher education program, and her field experiences in an international high school. The analysis spans macro-, meso-, and microlevels to explore the ways globalization, particularly immigration, as well as schooling policies for English language learners interact with aspects of Elena's core identity, particularly in school settings. The findings show some of the ways language and literacy verified and/or denied aspects of Elena's core identity; specific instances where second language proficiency was cast as power and privilege versus disadvantage according to ethnic, language, and class categorizations; and the struggles Elena, and other immigrant youth may face given the focus on English language acquisition and high stakes accountability in schools, at the expense of students' primary language proficiency and affirmation of core identity markers.

  12. ALMA Long Baseline Campaigns: Phase Characteristics of Atmosphere at Long Baselines in the Millimeter and Submillimeter Wavelengths

    NASA Astrophysics Data System (ADS)

    Matsushita, Satoki; Asaki, Yoshiharu; Fomalont, Edward B.; Morita, Koh-Ichiro; Barkats, Denis; Hills, Richard E.; Kawabe, Ryohei; Maud, Luke T.; Nikolic, Bojan; Tilanus, Remo P. J.; Vlahakis, Catherine; Whyborn, Nicholas D.

    2017-03-01

    We present millimeter- and submillimeter-wave phase characteristics measured between 2012 and 2014 of Atacama Large Millimeter/submillimeter Array long baseline campaigns. This paper presents the first detailed investigation of the characteristics of phase fluctuation and phase correction methods obtained with baseline lengths up to ˜15 km. The basic phase fluctuation characteristics can be expressed with the spatial structure function (SSF). Most of the SSFs show that the phase fluctuation increases as a function of baseline length, with a power-law slope of ˜0.6. In many cases, we find that the slope becomes shallower (average of ˜0.2-0.3) at baseline lengths longer than ˜1 km, namely showing a turn-over in SSF. These power law slopes do not change with the amount of precipitable water vapor (PWV), but the fitted constants have a weak correlation with PWV, so that the phase fluctuation at a baseline length of 10 km also increases as a function of PWV. The phase correction method using water vapor radiometers (WVRs) works well, especially for the cases where PWV > 1 {mm}, which reduces the degree of phase fluctuations by a factor of two in many cases. However, phase fluctuations still remain after the WVR phase correction, suggesting the existence of other turbulent constituent that cause the phase fluctuation. This is supported by occasional SSFs that do not exhibit any turn-over; these are only seen when the PWV is low (i.e., when the WVR phase correction works less effectively) or after WVR phase correction. This means that the phase fluctuation caused by this turbulent constituent is inherently smaller than that caused by water vapor. Since in these rare cases there is no turn-over in the SSF up to the maximum baseline length of ˜15 km, this turbulent constituent must have scale height of 10 km or more, and thus cannot be water vapor, whose scale height is around 1 km. Based on the characteristics, this large scale height turbulent constituent is likely

  13. 75 FR 70732 - Notice of Baseline Filings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-18

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR11-71-000; Docket No. PR11-72-000; Docket No. PR11-73- 000] Notice of Baseline Filings November 10, 2010. Docket No. PR11-71-000..., 2010, the applicants listed above submitted their baseline filing of their Statement of Operating...

  14. Impacts of extreme flooding on riverbank filtration water quality.

    PubMed

    Ascott, M J; Lapworth, D J; Gooddy, D C; Sage, R C; Karapanos, I

    2016-06-01

    Riverbank filtration schemes form a significant component of public water treatment processes on a global level. Understanding the resilience and water quality recovery of these systems following severe flooding is critical for effective water resources management under potential future climate change. This paper assesses the impact of floodplain inundation on the water quality of a shallow aquifer riverbank filtration system and how water quality recovers following an extreme (1 in 17 year, duration >70 days, 7 day inundation) flood event. During the inundation event, riverbank filtrate water quality is dominated by rapid direct recharge and floodwater infiltration (high fraction of surface water, dissolved organic carbon (DOC) >140% baseline values, >1 log increase in micro-organic contaminants, microbial detects and turbidity, low specific electrical conductivity (SEC) <90% baseline, high dissolved oxygen (DO) >400% baseline). A rapid recovery is observed in water quality with most floodwater impacts only observed for 2-3 weeks after the flooding event and a return to normal groundwater conditions within 6 weeks (lower fraction of surface water, higher SEC, lower DOC, organic and microbial detects, DO). Recovery rates are constrained by the hydrogeological site setting, the abstraction regime and the water quality trends at site boundary conditions. In this case, increased abstraction rates and a high transmissivity aquifer facilitate rapid water quality recoveries, with longer term trends controlled by background river and groundwater qualities. Temporary reductions in abstraction rates appear to slow water quality recoveries. Flexible operating regimes such as the one implemented at this study site are likely to be required if shallow aquifer riverbank filtration systems are to be resilient to future inundation events. Development of a conceptual understanding of hydrochemical boundaries and site hydrogeology through monitoring is required to assess the

  15. A baseline study of the health status of the residents in Kalapana, Hawaii, January--June 1987

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Johnson, David B.; Arbeit, William, R.

    1988-08-01

    A community health survey was conducted during the first five months of 1987 in Kalapana, Hawaii. Some 676 residents were interviewed during the study, which represents some 82% of all households in the community. The goal was to obtain base-line data on the health status of all community residents and ambient air quality, in order to evaluate any changes in health status of residents after geothermal development in the area.

  16. Baseline Response Levels Are a Nuisance in Infant Contingency Learning

    ERIC Educational Resources Information Center

    Millar, W. S.; Weir, Catherine

    2015-01-01

    The impact of differences in level of baseline responding on contingency learning in the first year was examined by considering the response acquisition of infants classified into baseline response quartiles. Whereas the three lower baseline groups showed the predicted increment in responding to a contingency, the highest baseline responders did…

  17. Using health care audit to improve quality of clinical records: the preliminary experience of an Italian Cancer Institute.

    PubMed

    Cadeddu, Chiara; Specchia, Maria Lucia; Cacciatore, Pasquale; Marchini, Raffaele; Ricciardi, Walter; Cavuto, Costanza

    2017-01-01

    Audit and feedback are recognized as part of a strategy for improving performance and supporting quality and safety in European health care systems. These considerations led the Clinical Management Staff of the "Regina Elena" Italian Cancer Institute to start a project of self-assessment of the quality of clinical records and organizational appropriateness through a retrospective review. The evaluation about appropriateness and congruity concerned both clinical records of 2013 and of 2015. At the end of the assessment of clinical records of each Care Unit, results were shared with medical staff in scheduled audit meetings. One hundred and thirteen clinical records (19%) did not meet congruity criteria, while 74 (12.6%) resulted as inappropriate. Considering the economic esteem calculated from the difference between Diagnosis Related Groups (DRG) primarily identified as main diagnosis and main surgical intervention or procedure and those modified during the Local Health Unit (LHU) assessment, 2 surgical Care Units produced a high negative difference in terms of economic value with a consequent drop of hospital discharge form (named in Italian "scheda di dimissione ospedaliera", SDO) remuneration, 7 Care Units produced about the same medium difference with almost no change as SDO remuneration, and 2 Care Units had a positive difference with a profit in terms of SDO remuneration. Concerning the quality assessment of clinical records of 2015, the most critical areas were related to medical documents and hospital discharge form compilation. Our experience showed the effectiveness of clinical audit in assessing the quality of filling in medical records and the appropriateness of hospital admissions and the acceptability of this tool by clinicians.

  18. A pragmatic randomized comparative effectiveness trial of transitional care for a socioeconomically diverse population: Design, rationale and baseline characteristics.

    PubMed

    Schaeffer, Christine; Teter, Caroline; Finch, Emily A; Hurt, Courtney; Keeter, Mary Kate; Liss, David T; Rogers, Angela; Sheth, Avani; Ackermann, Ronald

    2018-02-01

    Transitional care programs have been widely used to reduce readmissions and improve the quality and safety of the handoff process between hospital and outpatient providers. Very little is known about effective transitional care interventions among patients who are uninsured or with Medicaid. This paper describes the design and baseline characteristics of a pragmatic randomized comparative effectiveness trial of transitional care. Northwestern Medical Group- Transitional Care (NMG-TC) care model was developed to address the needs of patients with multiple medical problems that required lifestyle changes and were amenable to office-based management. We present the design, evaluation methods and baseline characteristics of NMG-TC trial patients. Baseline demographic characteristics indicate that our patient population is predominantly male, Medicaid insured and non-white. This study will evaluate two methods for implementing an effective transitional care model in a medically complex and socioeconomically diverse population. Copyright © 2017 Elsevier Inc. All rights reserved.

  19. 40 CFR 80.93 - Individual baseline submission and approval.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... of its individual baseline to EPA (Fuel Studies and Standards Branch, Baseline Submission, U.S. EPA... Studies and Standards Branch, Baseline Petition, U.S. EPA, 2565 Plymouth Road, Ann Arbor, Michigan 48105..., used in the determination of a given fuel parameter; (iii) Identification of test method. If not per...

  20. 40 CFR 80.93 - Individual baseline submission and approval.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... of its individual baseline to EPA (Fuel Studies and Standards Branch, Baseline Submission, U.S. EPA... Studies and Standards Branch, Baseline Petition, U.S. EPA, 2565 Plymouth Road, Ann Arbor, Michigan 48105..., used in the determination of a given fuel parameter; (iii) Identification of test method. If not per...

  1. 40 CFR 80.93 - Individual baseline submission and approval.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... of its individual baseline to EPA (Fuel Studies and Standards Branch, Baseline Submission, U.S. EPA... Studies and Standards Branch, Baseline Petition, U.S. EPA, 2565 Plymouth Road, Ann Arbor, Michigan 48105..., used in the determination of a given fuel parameter; (iii) Identification of test method. If not per...

  2. 40 CFR 80.93 - Individual baseline submission and approval.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... of its individual baseline to EPA (Fuel Studies and Standards Branch, Baseline Submission, U.S. EPA... Studies and Standards Branch, Baseline Petition, U.S. EPA, 2565 Plymouth Road, Ann Arbor, Michigan 48105..., used in the determination of a given fuel parameter; (iii) Identification of test method. If not per...

  3. The importance of archiving baseline wilderness data

    Treesearch

    David N. Cole

    2007-01-01

    Baseline wilderness data are of considerable importance for several reasons. One of the primary values of wilderness is as a reference that contrasts with those lands where humans dominate the landscape. Leopold (1941) called wilderness "a base-datum of normality, a picture of how healthy land maintains itself." To realize this value, baseline data on...

  4. Baseline budgeting for continuous improvement.

    PubMed

    Kilty, G L

    1999-05-01

    This article is designed to introduce the techniques used to convert traditionally maintained department budgets to baseline budgets. This entails identifying key activities, evaluating for value-added, and implementing continuous improvement opportunities. Baseline Budgeting for Continuous Improvement was created as a result of a newly named company president's request to implement zero-based budgeting. The president was frustrated with the mind-set of the organization, namely, "Next year's budget should be 10 to 15 percent more than this year's spending." Zero-based budgeting was not the answer, but combining the principles of activity-based costing and the Just-in-Time philosophy of eliminating waste and continuous improvement did provide a solution to the problem.

  5. Passive range estimation using dual baseline triangulation

    NASA Astrophysics Data System (ADS)

    Pieper, Ronald J.; Cooper, Alfred W.; Pelegris, G.

    1996-03-01

    Modern combat systems based on active radar sensing suffer disadvantages against low-flying targets in cluttered backgrounds. Use of passive infrared sensors with these systems, either in cooperation or as an alternative, shows potential for improving target detection and declaration range for targets crossing the horizon. Realization of this potential requires fusion of target position data from dissimilar sensors, or passive sensor measurement of target range. The availability of passive sensors that can supply both range and bearing data on such targets would significantly extend the robustness of an integrated ship self-defense system. This paper considers a new method of range determination with passive sensors based on the principle of triangulation, extending the principle to two orthogonal baselines. The performance of single or double baseline triangulation depends on sensor bearing precision and direction to target. An expression for maximum triangulation range at a required accuracy is derived as a function of polar angle relative to the center of the dual-baseline system. Limitations in the dual- baseline model due to the geometrically assessed horizon are also considered.

  6. Preliminary design study of a baseline MIUS

    NASA Technical Reports Server (NTRS)

    Wolfer, B. M.; Shields, V. E.; Rippey, J. O.; Roberts, H. L.; Wadle, R. C.; Wallin, S. P.; Gill, W. L.; White, E. H.; Monzingo, R.

    1977-01-01

    Results of a conceptual design study to establish a baseline design for a modular integrated utility system (MIUS) are presented. The system concept developed a basis for evaluating possible projects to demonstrate an MIUS. For the baseline study, climate conditions for the Washington, D.C., area were used. The baseline design is for a high density apartment complex of 496 dwelling units with a planned full occupancy of approximately 1200 residents. Environmental considerations and regulations for the MIUS installation are discussed. Detailed cost data for the baseline MIUS are given together with those for design and operating variations under climate conditions typified by Las Vegas, Nevada, Houston, Texas, and Minneapolis, Minnesota. In addition, results of an investigation of size variation effects, for 300 and 1000 unit apartment complexes, are presented. Only conceptual aspects of the design are discussed. Results regarding energy savings and costs are intended only as trend information and for use in relative comparisons. Alternate heating, ventilation, and air conditioning concepts are considered in the appendix.

  7. Safe and sensible preprocessing and baseline correction of pupil-size data.

    PubMed

    Mathôt, Sebastiaan; Fabius, Jasper; Van Heusden, Elle; Van der Stigchel, Stefan

    2018-02-01

    Measurement of pupil size (pupillometry) has recently gained renewed interest from psychologists, but there is little agreement on how pupil-size data is best analyzed. Here we focus on one aspect of pupillometric analyses: baseline correction, i.e., analyzing changes in pupil size relative to a baseline period. Baseline correction is useful in experiments that investigate the effect of some experimental manipulation on pupil size. In such experiments, baseline correction improves statistical power by taking into account random fluctuations in pupil size over time. However, we show that baseline correction can also distort data if unrealistically small pupil sizes are recorded during the baseline period, which can easily occur due to eye blinks, data loss, or other distortions. Divisive baseline correction (corrected pupil size = pupil size/baseline) is affected more strongly by such distortions than subtractive baseline correction (corrected pupil size = pupil size - baseline). We discuss the role of baseline correction as a part of preprocessing of pupillometric data, and make five recommendations: (1) before baseline correction, perform data preprocessing to mark missing and invalid data, but assume that some distortions will remain in the data; (2) use subtractive baseline correction; (3) visually compare your corrected and uncorrected data; (4) be wary of pupil-size effects that emerge faster than the latency of the pupillary response allows (within ±220 ms after the manipulation that induces the effect); and (5) remove trials on which baseline pupil size is unrealistically small (indicative of blinks and other distortions).

  8. Efficient Wide Baseline Structure from Motion

    NASA Astrophysics Data System (ADS)

    Michelini, Mario; Mayer, Helmut

    2016-06-01

    This paper presents a Structure from Motion approach for complex unorganized image sets. To achieve high accuracy and robustness, image triplets are employed and (an approximate) camera calibration is assumed to be known. The focus lies on a complete linking of images even in case of large image distortions, e.g., caused by wide baselines, as well as weak baselines. A method for embedding image descriptors into Hamming space is proposed for fast image similarity ranking. The later is employed to limit the number of pairs to be matched by a wide baseline method. An iterative graph-based approach is proposed formulating image linking as the search for a terminal Steiner minimum tree in a line graph. Finally, additional links are determined and employed to improve the accuracy of the pose estimation. By this means, loops in long image sequences are implicitly closed. The potential of the proposed approach is demonstrated by results for several complex image sets also in comparison with VisualSFM.

  9. Family Day Care Educators' Knowledge, Confidence and Skills in Promoting Children's Social and Emotional Wellbeing: Baseline Data from Thrive

    ERIC Educational Resources Information Center

    Davis, Elise; Corr, Lara; Ummer-Christian, Rahila; Gilson, Kim-Michelle; Waters, Elizabeth; Mihalopoulos, Cathrine; Marshall, Bernie; Cook, Kay; Herman, Helen; Mackinnon, Andrew; Harrsion, Linda; Sims, Margaret

    2014-01-01

    This paper presents baseline data from Thrive, a capacity-building program for family day care educators. Educators completed a self-report survey assessing knowledge and confidence in promoting children's social and emotional wellbeing. An in-home observation was used to assess care quality. Twenty-four educators responded to the survey (40 per…

  10. Effect of Store and Forward Teledermatology on Quality of Life

    PubMed Central

    Whited, John D.; Warshaw, Erin M.; Edison, Karen E.; Kapur, Kush; Thottapurathu, Lizy; Raju, Srihari; Cook, Bethany; Engasser, Holly; Pullen, Samantha; Parks, Patricia; Sindowski, Tom; Motyka, Danuta; Brown, Rodney; Moritz, Thomas E.; Datta, Santanu K.; Chren, Mary-Margaret; Marty, Lucinda; Reda, Domenic J.

    2013-01-01

    Importance Although research on quality of life and dermatologic conditions is well represented in the literature, information on teledermatology’s effect on quality of life is virtually absent. Objective To determine the effect of store and forward teledermatology on quality of life. Design Two-site, parallel-group, superiority randomized controlled trial. Setting Dermatology clinics and affiliated sites of primary care at 2 US Department of Veterans Affairs medical facilities. Participants Patients being referred to a dermatology clinic were randomly assigned, stratified by site, to teledermatology or the conventional consultation process. Among the 392 patients who met the inclusion criteria and were randomized, 326 completed the allocated intervention and were included in the analysis. Interventions Store and forward teledermatology (digital images and a standardized history) or conventional text-based consultation processes were used to manage the dermatology consultations. Patients were followed up for 9 months. Main Outcome Measures The primary end point was change in Skindex-16 scores, a skin-specific quality-of-life instrument, between baseline and 9 months. A secondary end point was change in Skindex-16 scores between baseline and 3 months. Results Patients in both randomization groups demonstrated a clinically significant improvement in Skindex-16 scores between baseline and 9 months with no significant difference by randomization group (P=.66, composite score). No significant difference in Skindex-16 scores by randomization group between baseline and 3 months was found (P=.39, composite score). Conclusions Compared with the conventional consultation process, store and forward teledermatology did not result in a statistically significant difference in skin-related quality of life at 3 or 9 months after referral. Trial Registration clinicaltrials.gov Identifier: NCT00488293 PMID:23426111

  11. Study design and baseline findings from the progression of ocular findings (PROOF) natural history study of dry eye.

    PubMed

    McDonnell, Peter J; Pflugfelder, Stephen C; Stern, Michael E; Hardten, David R; Conway, Taryn; Villanueva, Linda; Hollander, David A

    2017-12-28

    The aim of this research is to initiate a 5-year natural history study of dry eye disease (DED) using objectively assessed and patient-reported outcomes, to explore the hypothesis that DED is a progressive condition that has substantive and measurable impacts not only on the ocular surface, but on quality of life and visual functioning. Our objective for this report is to examine the baseline data. A multicenter, prospective, controlled, observational study of Level 2 (mild-to-moderate) DED patients based on International Task Force Delphi Panel severity grading, and controls, documented baseline measures (including tear film biomarkers and quality of life). Tear cytokine concentrations were also measured in the tear film. Patients were using artificial tears as needed. Two hundred seventeen DED patients and 67 gender- and age-matched controls were enrolled. A majority were females and Caucasian and groups did not differ significantly in terms of gender, race, or age. Differences between DED and matched controls, at baseline, included mean scores for Ocular Surface Disease Index (31.7 vs 4.1, P < 0.0001), Schirmer test (5.7 vs 15.3 mm, P < 0.0001), corneal staining (1.4 vs 0.2, P < 0.0001), conjunctival staining (1.4 vs 0.3, P < 0.0001), and tear break-up time (5.7 vs 8.5 s, P < 0.0001). Tear cytokines levels were determined and included interferon-γ, interleukin (IL)-1β, IL-2, IL-4, IL-6, IL-8, tumor necrosis factor-α, epidermal growth factor, IL-13, IL-17, IL-1α, and inducible protein-10. The mean levels of IL-8 and IL-6 were slightly higher in the DED group at baseline. Blurred vision was reported as moderate/severe/very severe at baseline in 57.6% of DED patients vs.10.5% of normal controls (P < 0.0001). DED patients reported greater reductions in work and non-work productivity, as well as greater need for visits to ophthalmologists during the prior year. In this report of the baseline findings of a 5-year natural history study of

  12. Smoothness of In vivo Spectral Baseline Determined by Mean Squared Error

    PubMed Central

    Zhang, Yan; Shen, Jun

    2013-01-01

    Purpose A nonparametric smooth line is usually added to spectral model to account for background signals in vivo magnetic resonance spectroscopy (MRS). The assumed smoothness of the baseline significantly influences quantitative spectral fitting. In this paper, a method is proposed to minimize baseline influences on estimated spectral parameters. Methods In this paper, the non-parametric baseline function with a given smoothness was treated as a function of spectral parameters. Its uncertainty was measured by root-mean-squared error (RMSE). The proposed method was demonstrated with a simulated spectrum and in vivo spectra of both short echo time (TE) and averaged echo times. The estimated in vivo baselines were compared with the metabolite-nulled spectra, and the LCModel-estimated baselines. The accuracies of estimated baseline and metabolite concentrations were further verified by cross-validation. Results An optimal smoothness condition was found that led to the minimal baseline RMSE. In this condition, the best fit was balanced against minimal baseline influences on metabolite concentration estimates. Conclusion Baseline RMSE can be used to indicate estimated baseline uncertainties and serve as the criterion for determining the baseline smoothness of in vivo MRS. PMID:24259436

  13. Haemophilia utilization group study - Part Va (HUGS Va): design, methods and baseline data.

    PubMed

    Zhou, Z-Y; Wu, J; Baker, J; Curtis, R; Forsberg, A; Huszti, H; Koerper, M; Lou, M; Miller, R; Parish, K; Riske, B; Shapiro, A; Ullman, M; Johnson, K

    2011-09-01

    To describe the study design, procedures and baseline characteristics of the Haemophilia Utilization Group Study - Part Va (HUGS Va), a US multi-center observational study evaluating the cost of care and burden of illness in persons with factor VIII deficiency. Patients with factor VIII level ≤ 30%, age 2-64 years, receiving treatment at one of six federally supported haemophilia treatment centres (HTCs) were enrolled in the study. Participants completed an initial interview including questions on socio-demographical characteristics, health insurance status, co-morbidities, access to care, haemophilia treatment regimen, factor utilization, self-reported joint pain and motion limitation and health-related quality of life. A periodic follow-up survey collected data regarding time lost from usual activities, disability days, health care utilization and outcomes of care. HTC clinicians documented participants' baseline clinical characteristics and pharmacy dispensing records for 2 years. Between July 2005 and July 2007, 329 participants were enrolled. Average age was 9.7 years for children and 33.5 years for adults; two-thirds had severe haemophilia. The distributions of age, marital status, education level and barriers to haemophilia care were relatively consistent across haemophilic severity categories. Differences were found in participants' employment status, insurance status and income. Overall, children with haemophilia had quality of life scores comparable to healthy counterparts. Adults had significantly lower physical functioning than the general US population. As one of the largest economic studies of haemophilia care, HUGS Va will provide detailed information regarding the burden of illness and health care utilization in the US haemophilia A population. © 2011 Blackwell Publishing Ltd.

  14. Association of baseline sex hormone levels with baseline and longitudinal changes in waist-to-hip ratio: Multi-Ethnic Study of Atherosclerosis.

    PubMed

    Vaidya, D; Dobs, A; Gapstur, S M; Golden, S H; Cushman, M; Liu, K; Ouyang, P

    2012-12-01

    Waist-to-hip ratio (WHR) is strongly associated with prevalent atherosclerosis. We analyzed the associations of baseline serum levels of testosterone (T), estradiol (E2), sex-hormone-binding globulin (SHBG) and dehydroepiandrosterone (DHEA) with WHR in the Multi-Ethnic Study of Atherosclerosis (MESA) cohort. Baseline data was available for 3144 men and 2038 postmenopausal women, who were non-users of hormone therapy, who were 45-84 years of age, and of White, Chinese, Black or Hispanic racial/ethnic groups. Of these, 2708 men and 1678 women also had longitudinal measurements of WHR measured at the second and/or the third study visits (median follow-up 578 days and 1135 days, respectively). In cross-sectional analyses adjusted for age, race and cardiovascular disease risk factors, T was negatively associated with baseline WHR in men, whereas in both sexes, E2 was positively associated and SHBG was negatively associated with WHR (all P<0.001). In longitudinal analyses, further adjusted for follow-up time and baseline WHR, baseline T was negatively associated with WHR at follow-up (P=0.001) in men, whereas in both sexes, E2 was positively associated (P=0.004) and SHBG was negatively associated with WHR (P<0.001). The longitudinal association of E2, but not T, was independent of SHBG. In cross-sectional or longitudinal analyses, there were no associations between DHEA and WHR in either men or women. Sex hormones are associated with WHR at baseline and also during follow-up above and beyond their baseline association. Future research is needed to determine if manipulation of hormones is associated with changes in central obesity.

  15. An Automated Baseline Correction Method Based on Iterative Morphological Operations.

    PubMed

    Chen, Yunliang; Dai, Liankui

    2018-05-01

    Raman spectra usually suffer from baseline drift caused by fluorescence or other reasons. Therefore, baseline correction is a necessary and crucial step that must be performed before subsequent processing and analysis of Raman spectra. An automated baseline correction method based on iterative morphological operations is proposed in this work. The method can adaptively determine the structuring element first and then gradually remove the spectral peaks during iteration to get an estimated baseline. Experiments on simulated data and real-world Raman data show that the proposed method is accurate, fast, and flexible for handling different kinds of baselines in various practical situations. The comparison of the proposed method with some state-of-the-art baseline correction methods demonstrates its advantages over the existing methods in terms of accuracy, adaptability, and flexibility. Although only Raman spectra are investigated in this paper, the proposed method is hopefully to be used for the baseline correction of other analytical instrumental signals, such as IR spectra and chromatograms.

  16. Diet quality of US adolescents during the transition to adulthood: changes and predictors12

    PubMed Central

    Lipsky, Leah M; Haynie, Denise L; Liu, Danping; Pratt, Charlotte A; Dempster, Katherine W

    2017-01-01

    Background: Influences on diet quality during the transition from adolescence to adulthood are understudied. Objective: This study examined association of 3 diet-quality indicators—Healthy Eating Index-2010 (HEI), Whole Plant Foods Density (WPF), and Empty Calories (EC; the percentage of calories from discretionary solid fat, added sugar and alcohol)—with lifestyle behaviors, baseline weight status, and sociodemographic characteristics in US emerging adults. Design: Data come from the first 4 waves (annual assessments) of the NEXT Plus Study, a population-based cohort of 10th graders enrolled in 2010 (n = 566). At each assessment, participants completed 3 nonconsecutive 24-h diet recalls, wore accelerometers for 7 d, and self-reported meal practices and sedentary behaviors. Self-reported sociodemographic characteristics were ascertained at baseline. Generalized estimating equations examined associations of time-varying diet quality with baseline weight status and sociodemographic characteristics and time-varying lifestyle behaviors. Results: Diet quality improved modestly from baseline (mean ± SE: HEI, 44.07 ± 0.53; WPF, 1.24 ± 0.04; and EC, 35.66 ± 0.55) to wave 4 for WPF (1.44 ± 0.05, P < 0.001) and EC (33.47 ± 0.52, P < 0.001), but not HEI (45.22 ± 0.60). In longitudinal analyses, higher HEI and lower EC scores were observed in Hispanic compared with white participants. Better diet quality was associated with greater moderate-to-vigorous physical activity, more frequent breakfast and family meals, less frequent fast food and meals during television viewing, and shorter durations of television viewing, gaming, and online social networking. Diet-quality indicators were not consistently associated with time-varying physical inactivity, baseline weight status, or sociodemographic characteristics. Conclusions: Diet quality of emerging adults in the US remained suboptimal, but some aspects improved marginally over the 4-y study period. Meal contexts and

  17. Baseline serum CXCL10 and IL-12 levels may predict severe asthmatics' responsiveness to omalizumab.

    PubMed

    Suzukawa, Maho; Matsumoto, Hisako; Ohshima, Nobuharu; Tashimo, Hiroyuki; Asari, Isao; Tajiri, Tomoko; Niimi, Akio; Nagase, Hiroyuki; Matsui, Hirotoshi; Kobayashi, Nobuyuki; Shoji, Shunsuke; Ohta, Ken

    2018-01-01

    Omalizumab, a humanized anti-IgE monoclonal antibody, is the first molecularly targeted drug for severe asthmatics. However, responses to omalizumab vary widely among patients. This study aimed to assess the potential of baseline serum cytokine levels as predictors of responsiveness to omalizumab. Thirty-one patients with severe, persistent asthma were enrolled in this study and administered omalizumab for at least 1 year. Response to omalizumab was assessed based on the physician's global evaluation of treatment effectiveness (GETE) at 48 weeks of treatment. Blood samples were collected at baseline and 16 and 32 weeks after starting omalizumab and measured for 30 cytokines by Luminex 200 and ELISA. Exhaled nitric oxide (FeNO) levels, peripheral blood eosinophil counts, pre-bronchodilator pulmonary functions and Asthma Quality of Life Questionnaire scores were determined at baseline and 16, 32 and 48 weeks after starting omalizumab. The numbers of clinically significant asthma exacerbations in the previous year and during 48 weeks of treatment with omalizumab were assessed. GETE assessment showed 19 responders (61.3%) and 12 non-responders (38.7%). Responders showed significantly higher levels of CXCL10 and IL-12 at baseline compared to non-responders (CXCL10: responders, 1530.0 ± 315.2 pg/ml vs. non-responders, 1066.0 ± 396.8 pg/ml, P = 0.001; IL-12: responders, 60.2 ± 39.2 pg/ml vs. non-responders, 32.2 ± 26.3 pg/ml, P = 0.04). ROC curves to distinguish responders from non-responders using the baseline serum CXCL10 level showed a good AUC of 0.83. At 32 weeks of omalizumab therapy, serum CXCL10 tended to be increased (1350 ± 412.3 pg/ml at baseline vs. 1529 ± 637.6 pg/ml at 32 weeks, P = 0.16) and serum IL-12 tended to be decreased (49.4 ± 37.0 pg/ml at baseline vs. 43.9 ± 30.9 pg/ml at 32 weeks, P = 0.05). On the other hand, serum IL-5 and PDGF were significantly decreased (IL-5: 54.2 ± 13.8 pg/ml at baseline vs. 49

  18. Treadmill Kinematics Baseline Data Collection

    NASA Image and Video Library

    2011-05-12

    PHOTO DATE: 5-12-11 LOCATION: Building 261 - Room 138 SUBJECT: Expedition 29 Preflight Training with Dan Burbank during Treadmill Kinematics Baseline Data Collection. WORK ORDER: 2011-1214 PHOTOGRAPHER: Lauren Harnett

  19. Baseline estimation from simultaneous satellite laser tracking

    NASA Technical Reports Server (NTRS)

    Dedes, George C.

    1987-01-01

    Simultaneous Range Differences (SRDs) to Lageos are obtained by dividing the observing stations into pairs with quasi-simultaneous observations. For each of those pairs the station with the least number of observations is identified, and at its observing epochs interpolated ranges for the alternate station are generated. The SRD observables are obtained by subtracting the actually observed laser range of the station having the least number of observations from the interpolated ranges of the alternate station. On the basis of these observables semidynamic single baseline solutions were performed. The aim of these solutions is to further develop and implement the SRD method in the real data environment, to assess its accuracy, its advantages and disadvantages as related to the range dynamic mode methods, when the baselines are the only parameters of interest. Baselines, using simultaneous laser range observations to Lageos, were also estimated through the purely geometric method. These baselines formed the standards the standards of comparison in the accuracy assessment of the SRD method when compared to that of the range dynamic mode methods. On the basis of this comparison it was concluded that for baselines of regional extent the SRD method is very effective, efficient, and at least as accurate as the range dynamic mode methods, and that on the basis of a simple orbital modeling and a limited orbit adjustment. The SRD method is insensitive to the inconsistencies affecting the terrestrial reference frame and simultaneous adjustment of the Earth Rotation Parameters (ERPs) is not necessary.

  20. Evaluation of Imaging Parameters of Ultrasound Scanners: Baseline for Future Testing

    PubMed Central

    Pasicz, Katarzyna; Grabska, Iwona; Skrzyński, Witold; Ślusarczyk-Kacprzyk, Wioletta; Bulski, Wojciech

    2017-01-01

    Summary Background Regular quality control is required in Poland only for those methods of medical imaging which involve the use of ionizing radiation but not for ultrasonography. It is known that the quality of ultrasound images may be affected by the wearing down or malfunctioning of equipment. Material/Methods An evaluation of image quality was carried out for 22 ultrasound scanners equipped with 46 transducers. The CIRS Phantom model 040GSE was used. A set of tests was established which could be carried out with the phantom, including: depth of penetration, dead zone, distance measurement accuracy, resolution, uniformity, and visibility of structures. Results While the dead zone was 0 mm for 89% of transducers, it was 3 mm for the oldest transducer. The distances measured agreed with the actual distances by 1 mm or less in most cases, with the largest difference of 2.6 mm. The resolution in the axial direction for linear transducers did not exceed 1 mm, but it reached even 5 mm for some of the convex and sector transducers, especially at higher depths and in the lateral direction. For 29% of transducers, some distortions of anechoic structures were observed. Artifacts were detected for several transducers. Conclusions The results will serve as a baseline for future testing. Several cases of suboptimal image quality were identified along with differences in performance between similar transducers. The results could be used to decide on the applicability of a given scanner or transducer for a particular kind of examination. PMID:29657644

  1. 38. View of niche in center bay of N room ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    38. View of niche in center bay of N room in mill ruins in which a painting or tapestry of Santa Elena was hung. - Hacienda Azurarera Santa Elena, Sugar Mill Ruins, 1.44 miles North of PR Route 2 Bridge Over Rio De La Plata, Toa Baja, Toa Baja Municipio, PR

  2. Baseline Optimization for the Measurement of CP Violation, Mass Hierarchy, and $$\\theta_{23}$$ Octant in a Long-Baseline Neutrino Oscillation Experiment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bass, M.; Bishai, M.; Cherdack, D.

    2015-03-19

    Next-generation long-baseline electron neutrino appearance experiments will seek to discover C P violation, determine the mass hierarchy and resolve the θ 23 octant. In light of the recent precision measurements of θ 13 , we consider the sensitivity of these measurements in a study to determine the optimal baseline, including practical considerations regarding beam and detector performance. We conclude that a detector at a baseline of at least 1000 km in a wide-band muon neutrino beam is themore » optimal configuration.« less

  3. 324 Building Baseline Radiological Characterization

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    R.J. Reeder, J.C. Cooper

    This report documents the analysis of radiological data collected as part of the characterization study performed in 1998. The study was performed to create a baseline of the radiological conditions in the 324 Building.

  4. Cause-specific premature death from ambient PM2.5 exposure in India: Estimate adjusted for baseline mortality.

    PubMed

    Chowdhury, Sourangsu; Dey, Sagnik

    2016-05-01

    In India, more than a billion population is at risk of exposure to ambient fine particulate matter (PM2.5) concentration exceeding World Health Organization air quality guideline, posing a serious threat to health. Cause-specific premature death from ambient PM2.5 exposure is poorly known for India. Here we develop a non-linear power law (NLP) function to estimate the relative risk associated with ambient PM2.5 exposure using satellite-based PM2.5 concentration (2001-2010) that is bias-corrected against coincident direct measurements. We show that estimate of annual premature death in India is lower by 14.7% (19.2%) using NLP (integrated exposure risk function, IER) for assumption of uniform baseline mortality across India (as considered in the global burden of disease study) relative to the estimate obtained by adjusting for state-specific baseline mortality using GDP as a proxy. 486,100 (811,000) annual premature death in India is estimated using NLP (IER) risk functions after baseline mortality adjustment. 54.5% of premature death estimated using NLP risk function is attributed to chronic obstructive pulmonary disease (COPD), 24.0% to ischemic heart disease (IHD), 18.5% to stroke and the remaining 3.0% to lung cancer (LC). 44,900 (5900-173,300) less premature death is expected annually, if India achieves its present annual air quality target of 40μgm(-3). Our results identify the worst affected districts in terms of ambient PM2.5 exposure and resulting annual premature death and call for initiation of long-term measures through a systematic framework of pollution and health data archive. Copyright © 2016 Elsevier Ltd. All rights reserved.

  5. First Grade Baseline Evaluation

    ERIC Educational Resources Information Center

    Center for Innovation in Assessment (NJ1), 2013

    2013-01-01

    The First Grade Baseline Evaluation is an optional tool that can be used at the beginning of the school year to help teachers get to know the reading and language skills of each student. The evaluation is composed of seven screenings. Teachers may use the entire evaluation or choose to use those individual screenings that they find most beneficial…

  6. Precise regional baseline estimation using a priori orbital information

    NASA Technical Reports Server (NTRS)

    Lindqwister, Ulf J.; Lichten, Stephen M.; Blewitt, Geoffrey

    1990-01-01

    A solution using GPS measurements acquired during the CASA Uno campaign has resulted in 3-4 mm horizontal daily baseline repeatability and 13 mm vertical repeatability for a 729 km baseline, located in North America. The agreement with VLBI is at the level of 10-20 mm for all components. The results were obtained with the GIPSY orbit determination and baseline estimation software and are based on five single-day data arcs spanning the 20, 21, 25, 26, and 27 of January, 1988. The estimation strategy included resolving the carrier phase integer ambiguities, utilizing an optial set of fixed reference stations, and constraining GPS orbit parameters by applying a priori information. A multiday GPS orbit and baseline solution has yielded similar 2-4 mm horizontal daily repeatabilities for the same baseline, consistent with the constrained single-day arc solutions. The application of weak constraints to the orbital state for single-day data arcs produces solutions which approach the precise orbits obtained with unconstrained multiday arc solutions.

  7. GPS baseline configuration design based on robustness analysis

    NASA Astrophysics Data System (ADS)

    Yetkin, M.; Berber, M.

    2012-11-01

    The robustness analysis results obtained from a Global Positioning System (GPS) network are dramatically influenced by the configurationof the observed baselines. The selection of optimal GPS baselines may allow for a cost effective survey campaign and a sufficiently robustnetwork. Furthermore, using the approach described in this paper, the required number of sessions, the baselines to be observed, and thesignificance levels for statistical testing and robustness analysis can be determined even before the GPS campaign starts. In this study, wepropose a robustness criterion for the optimal design of geodetic networks, and present a very simple and efficient algorithm based on thiscriterion for the selection of optimal GPS baselines. We also show the relationship between the number of sessions and the non-centralityparameter. Finally, a numerical example is given to verify the efficacy of the proposed approach.

  8. Measuring cognitive change with ImPACT: the aggregate baseline approach.

    PubMed

    Bruce, Jared M; Echemendia, Ruben J; Meeuwisse, Willem; Hutchison, Michael G; Aubry, Mark; Comper, Paul

    2017-11-01

    The Immediate Post-Concussion Assessment and Cognitive Test (ImPACT) is commonly used to assess baseline and post-injury cognition among athletes in North America. Despite this, several studies have questioned the reliability of ImPACT when given at intervals employed in clinical practice. Poor test-retest reliability reduces test sensitivity to cognitive decline, increasing the likelihood that concussed athletes will be returned to play prematurely. We recently showed that the reliability of ImPACT can be increased when using a new composite structure and the aggregate of two baselines to predict subsequent performance. The purpose of the present study was to confirm our previous findings and determine whether the addition of a third baseline would further increase the test-retest reliability of ImPACT. Data from 97 English speaking professional hockey players who had received at least 4 ImPACT baseline evaluations were extracted from a National Hockey League Concussion Program database. Linear regression was used to determine whether each of the first three testing sessions accounted for unique variance in the fourth testing session. Results confirmed that the aggregate baseline approach improves the psychometric properties of ImPACT, with most indices demonstrating adequate or better test-retest reliability for clinical use. The aggregate baseline approach provides a modest clinical benefit when recent baselines are available - and a more substantial benefit when compared to approaches that obtain baseline measures only once during the course of a multi-year playing career. Pending confirmation in diverse samples, neuropsychologists are encouraged to use the aggregate baseline approach to best quantify cognitive change following sports concussion.

  9. Moon-Based INSAR Geolocation and Baseline Analysis

    NASA Astrophysics Data System (ADS)

    Liu, Guang; Ren, Yuanzhen; Ye, Hanlin; Guo, Huadong; Ding, Yixing; Ruan, Zhixing; Lv, Mingyang; Dou, Changyong; Chen, Zhaoning

    2016-07-01

    Earth observation platform is a host, the characteristics of the platform in some extent determines the ability for earth observation. Currently most developing platforms are satellite, in contrast carry out systematic observations with moon based Earth observation platform is still a new concept. The Moon is Earth's only natural satellite and is the only one which human has reached, it will give people different perspectives when observe the earth with sensors from the moon. Moon-based InSAR (SAR Interferometry), one of the important earth observation technology, has all-day, all-weather observation ability, but its uniqueness is still a need for analysis. This article will discuss key issues of geometric positioning and baseline parameters of moon-based InSAR. Based on the ephemeris data, the position, liberation and attitude of earth and moon will be obtained, and the position of the moon-base SAR sensor can be obtained by coordinate transformation from fixed seleno-centric coordinate systems to terrestrial coordinate systems, together with the Distance-Doppler equation, the positioning model will be analyzed; after establish of moon-based InSAR baseline equation, the different baseline error will be analyzed, the influence of the moon-based InSAR baseline to earth observation application will be obtained.

  10. In-Situ and Remotely-Sensed Observations of Biomass Burning Aerosols at Doi Ang Khang, Thailand During 7-SEAS BASELInE 2015

    NASA Technical Reports Server (NTRS)

    Sayer, Andrew M.; Hsu, N. Christina; Hsiao, Ta-Chih; Pantina, Peter; Kuo, Ferret; Ou-Yang, Chang-Feng; Holben, Brent N.; Janjai, Serm; Chantara, Somporn; Wang, Sheng-Hsiang; hide

    2016-01-01

    The spring 2015 deployment of a suite of instrumentation at Doi Ang Khang (DAK) in northwestern Thailand enabled the characterization of air masses containing smoke aerosols from burning predominantly in Myanmar. Aerosol Robotic Network (AERONET) Sun photometer data were used to validate Moderate Resolution Imaging Spectroradiometer (MODIS) Collection 6 "Deep Blue" aerosol optical depth (AOD) retrievals; MODIS Terra and Aqua provided results of similar quality, with correlation coefficients of 0.93-0.94 and similar agreement within expected uncertainties to global-average performance. Scattering and absorption measurements were used to compare surface and total column aerosol single scatter albedo (SSA); while the two were well-correlated, and showed consistent positive relationships with moisture (increasing SSA through the season as surface relative humidity and total columnar water vapor increased), in situ surface-level SSA was nevertheless significantly lower by 0.12-0.17. This could be related to vertical heterogeneity and/or instrumental issues. DAK is at approximately 1,500 meters above sea level in heterogeneous terrain, and the resulting strong diurnal variability in planetary boundary layer depth above the site leads to high temporal variability in both surface and column measurements, and acts as a controlling factor to the ratio between surface particulate matter (PM) levels and column AOD. In contrast, while some hygroscopic effects were observed relating to aerosol particle size and Angstrom exponent, relative humidity variations appear to be less important for this ratio here. As part of the Seven South-East Asian Studies (7-SEAS) project, the Biomass-burning Aerosols & Stratocumulus Environment: Lifecycles and Interactions Experiment (BASELInE) was intended to probe physicochemical processes, interactions, and feedbacks related to biomass burning aerosols and clouds during the spring burning season (February-April) in southeast Asia (SEA).

  11. Study on the calibration and optimization of double theodolites baseline

    NASA Astrophysics Data System (ADS)

    Ma, Jing-yi; Ni, Jin-ping; Wu, Zhi-chao

    2018-01-01

    For the double theodolites measurement system baseline as the benchmark of the scale of the measurement system and affect the accuracy of the system, this paper puts forward a method for calibration and optimization of the double theodolites baseline. Using double theodolites to measure the known length of the reference ruler, and then reverse the baseline formula. Based on the error propagation law, the analyses show that the baseline error function is an important index to measure the accuracy of the system, and the reference ruler position, posture and so on have an impact on the baseline error. The optimization model is established and the baseline error function is used as the objective function, and optimizes the position and posture of the reference ruler. The simulation results show that the height of the reference ruler has no effect on the baseline error; the posture is not uniform; when the reference ruler is placed at x=500mm and y=1000mm in the measurement space, the baseline error is the smallest. The experimental results show that the experimental results are consistent with the theoretical analyses in the measurement space. In this paper, based on the study of the placement of the reference ruler, for improving the accuracy of the double theodolites measurement system has a reference value.

  12. 40 CFR 80.295 - How is a refinery sulfur baseline determined?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false How is a refinery sulfur baseline... PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Sulfur Abt Program-Baseline Determination § 80.295 How is a refinery sulfur baseline determined? (a) A refinery's gasoline sulfur baseline...

  13. 40 CFR 80.295 - How is a refinery sulfur baseline determined?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 16 2011-07-01 2011-07-01 false How is a refinery sulfur baseline... PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Sulfur Abt Program-Baseline Determination § 80.295 How is a refinery sulfur baseline determined? (a) A refinery's gasoline sulfur baseline...

  14. 40 CFR 80.295 - How is a refinery sulfur baseline determined?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 17 2013-07-01 2013-07-01 false How is a refinery sulfur baseline... PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Sulfur Abt Program-Baseline Determination § 80.295 How is a refinery sulfur baseline determined? (a) A refinery's gasoline sulfur baseline...

  15. 40 CFR 80.295 - How is a refinery sulfur baseline determined?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 17 2012-07-01 2012-07-01 false How is a refinery sulfur baseline... PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Sulfur Abt Program-Baseline Determination § 80.295 How is a refinery sulfur baseline determined? (a) A refinery's gasoline sulfur baseline...

  16. 40 CFR 80.295 - How is a refinery sulfur baseline determined?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 17 2014-07-01 2014-07-01 false How is a refinery sulfur baseline... PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Sulfur Abt Program-Baseline Determination § 80.295 How is a refinery sulfur baseline determined? (a) A refinery's gasoline sulfur baseline...

  17. Advanced Imaging Methods for Long-Baseline Optical Interferometry

    NASA Astrophysics Data System (ADS)

    Le Besnerais, G.; Lacour, S.; Mugnier, L. M.; Thiebaut, E.; Perrin, G.; Meimon, S.

    2008-11-01

    We address the data processing methods needed for imaging with a long baseline optical interferometer. We first describe parametric reconstruction approaches and adopt a general formulation of nonparametric image reconstruction as the solution of a constrained optimization problem. Within this framework, we present two recent reconstruction methods, Mira and Wisard, representative of the two generic approaches for dealing with the missing phase information. Mira is based on an implicit approach and a direct optimization of a Bayesian criterion while Wisard adopts a self-calibration approach and an alternate minimization scheme inspired from radio-astronomy. Both methods can handle various regularization criteria. We review commonly used regularization terms and introduce an original quadratic regularization called ldquosoft support constraintrdquo that favors the object compactness. It yields images of quality comparable to nonquadratic regularizations on the synthetic data we have processed. We then perform image reconstructions, both parametric and nonparametric, on astronomical data from the IOTA interferometer, and discuss the respective roles of parametric and nonparametric approaches for optical interferometric imaging.

  18. The effects of lacosamide on cognition, quality-of-life measures, and quality of life in patients with refractory partial epilepsy.

    PubMed

    Lancman, Marcelo E; Fertig, Evan J; Trobliger, Robert W; Perrine, Kenneth; Myers, Lorna; Iyengar, Sloka S; Malik, Munazza

    2016-08-01

    The objective of this study was to examine cognitive and quality-of-life measures/quality of life outcomes with adjunctive lacosamide therapy in patients with treatment-resistant partial epilepsy. This was a prospective, open-label, nonblinded, adjunctive therapy test-retest (within subjects) study of patients with treatment-resistant partial epilepsy in which outcome (cognitive functioning and mood/quality of life) was measured in the same subject before and after adjunctive lacosamide administration for 24weeks. The cognitive assessment included the following: Controlled Oral Word Association Test, Buschke Selective Reminding Test, Brief Visuospatial Memory Test-Revised, Stroop Color Word Test, Symbol Digit Modalities Test, Digit Span, Digit Cancellation, and Trails A and B. The quality-of-life measures/quality-of-life assessment included the following: Beck Depression Inventory-II, Profile of Mood States, and Quality of Life Inventory-89. Lacosamide was started at 100mg (50mg twice daily) and could be titrated as needed up to 400mg/day (200mg twice daily). Baseline concomitant AEDs were kept constant. Composite scores were calculated for a pre-post difference score for the cognitive and mood/quality-of-life measures separately and used in regression analyses to correct for the effects of age, education, seizure frequency, seizure severity, dose of lacosamide, and number of AEDs at baseline. Thirty-four patients were enrolled (13 males, 21 females). Mean age was 38.8±2.43years. Mean seizure frequency decreased significantly from 2.0±2.55 seizures per week at baseline to 1.02±1.72 seizures per week at posttreatment (t=4.59, p<.0001) with a 50% responder rate seen in 18 patients (52.9%). No significant differences were found on the composite scores of the cognitive or the mood/quality-of-life measures after 6months of lacosamide. Lacosamide appeared to have low risks of significant changes in cognition or mood/quality of life. In addition, the present study

  19. Perceived stress mediates the relationship between emotional loneliness and sleep quality over time in older adults.

    PubMed

    McHugh, Joanna E; Lawlor, Brian A

    2013-09-01

    Both loneliness and poor sleep quality are common occurrences in late life and both are detrimental to physical and mental health. While loneliness may be difficult to intervene upon, there may be correlated factors, which, if alleviated, could mitigate the effects of loneliness and sleep quality on health in late life. A longitudinal, observational study whereby we gathered predictive variables at baseline and dependent variable (sleep) at follow-up. We investigated the relationship between loneliness at baseline and sleep quality at follow-up in a group of 447 older adults attending the clinic for research participation. Loneliness, stress and sleep quality were all measured using self-report validated psychometric tools. We found that loneliness, specifically emotional loneliness, predicted sleep quality at follow-up, controlling for demographic factors and for sleep quality at baseline. Upon applying mediation methods to the data, we then found that this relationship was mediated in part by perceived stress. We conclude that the impact of emotional loneliness on sleep quality in older adults is partly because of the stress experienced as a result of feeling lonely. © 2012 The British Psychological Society.

  20. Hyperbaric oxygen for mild traumatic brain injury: Design and baseline summary.

    PubMed

    Weaver, Lindell K; Chhoeu, Austin; Lindblad, Anne S; Churchill, Susan; Wilson, Steffanie H

    2016-01-01

    The Brain Injury and Mechanisms of Action of Hyperbaric Oxygen for Persistent Post-Concussive Symptoms after Mild Traumatic Brain Injury (mTBI) (BIMA) study, sponsored by the Department of Defense, is a randomized double-blind, sham-controlled clinical trial that has a longer duration of follow-up and more comprehensive assessment battery compared to recent HBO₂ studies. BIMA randomized 71 participants from September 2012 to May 2014. Primary results are expected in 2017. Randomized military personnel received hyperbaric oxygen (HBO₂) at 1.5 atmospheres absolute (ATA) or sham chamber sessions at 1.2 ATA, air, for 60 minutes daily for 40 sessions. Outcomes include neuropsychological, neuroimaging, neurological, vestibular, autonomic function, electroencephalography, and visual systems evaluated at baseline, immediately following intervention at 13 weeks and six months with self-report symptom and quality of life questionnaires at 12 months, 24 months and 36 months. Characteristics include: median age 33 years (range 21-53); 99% male; 82% Caucasian; 49% diagnosed post-traumatic stress disorder; 28% with most recent injury three months to one year prior to enrollment; 32% blast injuries; and 73% multiple injuries. This manuscript describes the study design, outcome assessment battery, and baseline characteristics. Independent of a therapeutic role of HBO₂, results of BIMA will aid understanding of mTBI. ClinicalTrials.gov Identifier: NCT01611194; https://clinicaltrials.gov/show/NCT01611194. Copyright© Undersea and Hyperbaric Medical Society.

  1. Operational CryoSat Product Quality Assessment

    NASA Astrophysics Data System (ADS)

    Mannan, Rubinder; Webb, Erica; Hall, Amanda; Bouzinac, Catherine

    2013-12-01

    The performance and quality of the CryoSat data products are routinely assessed by the Instrument Data quality Evaluation and Analysis Service (IDEAS). This information is then conveyed to the scientific and user community in order to allow them to utilise CryoSat data with confidence. This paper presents details of the Quality Control (QC) activities performed for CryoSat products under the IDEAS contract. Details of the different QC procedures and tools deployed by IDEAS to assess the quality of operational data are presented. The latest updates to the Instrument Processing Facility (IPF) for the Fast Delivery Marine (FDM) products and the future update to Baseline-C are discussed.

  2. [Relationships of positive and negative affectivity to sleep quality in Japanese civil servants: 3-year follow-up study].

    PubMed

    Saeki, Urara; Nasermoaddeli, Ali; Sekine, Michikazu; Kagamimori, Sadanobu

    2008-11-01

    We conducted this longitudinal study to evaluate the relationships of positive and negative affectivity (Affect Balance Scale) to sleep quality among civil servants. For this study we evaluated 827 civil servants of T city in Toyama prefecture in the springs of 2001 (Baseline) and 2004 with complete information in both phases of the study. Based on the median score at each phase, we divided Affect Balance Scale (ABS) scores into high and low groups. We conducted logistic regression analysis to determine the odds ratios (OR) of 3-yr follow-up sleep quality by baseline and follow-up ABS scores. After adjusting for baseline sleep quality scores, age, sex, employment, job strain, and exercise habits, participants who had high ABS scores were more likely (OR: 3.13, 95% confidence interval (CI): 1.78-5.53) to have better sleep quality than those with low ABS scores at both phases. In addition, participants with low ABS scores at baseline and high ABS scores 3 yr later had better sleep quality (OR: 1.81, 95%CI: 1.02-3.20) than those with low ABS scores at both phases. These findings substantiate the relationships of positive and negative affectivity to sleep quality. Improving the affect balance condition as well as maintaining good affect balance condition may be important determinants of sleep quality in civil servants.

  3. BASELINE FEATURES AND DIFFERENCES IN 48 WEEK CLINICAL OUTCOMES IN PATIENTS WITH GASTROPARESIS AND TYPE 1 VERSUS TYPE 2 DIABETES

    PubMed Central

    Koch, Kenneth L.; Hasler, William L.; Yates, Katherine P.; Parkman, Henry P.; Pasricha, Pankaj J.; Calles-Escandon, Jorge; Snape, William J.; Abell, Thomas L.; McCallum, Richard W.; Nguyen, Linda A.; Sarosiek, Irene; Farrugia, Gianrico; Tonascia, James; Lee, Linda; Miriel, Laura; Hamilton, Frank

    2016-01-01

    Background In studies of diabetic gastroparesis, patients with type 1 and type 2 diabetes (T1DM, T2DM) are often combined for analyses. We compared gastroparesis severity, healthcare utilization, psychological function, and quality of life in T1DM versus T2DM gastroparesis patients. Methods Questionnaire, laboratory, and scintigraphy data from patients with gastroparesis and T1DM and T2DM from seven centers of the NIDDK Gastroparesis Clinical Research Consortium (GpCRC) Registry were compared at enrollment and after 48 weeks. Multiple regression models assessed baseline and follow-up differences between diabetes subtypes. Key Results At baseline, T1DM patients (N=78) had slower gastric emptying, more hospitalizations, more gastric stimulator implantations, higher hemoglobin A1c (HbA1c), and more anxiety versus T2DM patients (N=59). Independent discriminators of patients with T1DM versus T2DM included worse GERD, less bloating, more peripheral neuropathy, and fewer comorbidities (P≤0.05). On follow-up, gastrointestinal (GI) symptom scores decreased only in T2DM (P<0.05), but not in T1DM patients who reported greater prokinetic, proton pump inhibitor, anxiolytic, and gastric stimulator usage over 48 weeks (P≤0.03). GI symptoms at baseline and 48 weeks with both subtypes were not associated with HbA1c, peripheral neuropathy, psychological factors, or quality of life. Conclusions & Inferences Baseline symptoms were similar in T1DM and T2DM patients, even though T1DM patients had worse gastric emptying delays and higher HbA1c suggesting other factors mediate symptom severity. Symptom scores at 48 weeks decreased in T2DM but not T1DM patients, despite increased medical and surgical treatment utilization by T1DM patients. Defining causes of different outcomes in diabetic gastroparesis warrants further investigation. PMID:26946489

  4. Baseline Demographic, Anthropometric, Psychosocial, and Behavioral Characteristics of Rural, Southern Women in Early Pregnancy.

    PubMed

    Thomson, Jessica L; Tussing-Humphreys, Lisa M; Goodman, Melissa H; Olender, Sarah

    2016-09-01

    Objectives Beginning life in a healthy uterine environment is essential for future well-being, particularly as it relates to chronic disease risk. Baseline (early pregnancy) demographic, anthropometric (height and weight), psychosocial (depression and perceived stress), and behavioral (diet and exercise) characteristics of rural, Southern, pregnant women enrolled in a maternal, infant, and early childhood home visiting program are described. Methods Participants included 82 women early in their second trimester of pregnancy and residing in three Lower Mississippi Delta counties in the United States. Baseline data were collected through direct measurement and surveys. Results Participants were primarily African American (96 %), young (mean age = 23 years), single (93 %), and received Medicaid (92 %). Mean gestational age was 18 weeks, 67 % of participants were overweight or obese before becoming pregnant, and 16 % tested positive for major depression. Participants were sedentary (mean minutes of moderate intensity physical activity/week = 30), had low diet quality (mean Healthy Eating Index-2010 total score = 43 points), with only 38, 4, and 7 % meeting recommendations for saturated fat, fiber, and sodium intakes, respectively. Conclusions for Practice In the Lower Mississippi Delta, there is a need for interventions that are designed to help women achieve optimal GWG by improving their diet quality and increasing the amount of physical activity performed during pregnancy. Researchers also should consider addressing barriers to changing health behaviors during pregnancy that may be unique to this region of the United States.

  5. Deformation Monitoring of the Submillimetric UPV Calibration Baseline

    NASA Astrophysics Data System (ADS)

    García-Asenjo, Luis; Baselga, Sergio; Garrigues, Pascual

    2017-06-01

    A 330 m calibration baseline was established at the Universitat Politècnica de València (UPV) in 2007. Absolute scale was subsequently transferred in 2012 from the Nummela Standard Baseline in Finland and distances between pillars were determined with uncertainties ranging from 0.1 mm to 0.3 mm. In order to assess the long-term stability of the baseline three field campaigns were carried out from 2013 to 2015 in a co-operative effort with the Universidad Complutense de Madrid (UCM), which provided the only Mekometer ME5000 distance meter available in Spain. Since the application of the ISO17123-4 full procedure did not suffice to come to a definite conclusion about possible displacements of the pillars, we opted for the traditional geodetic network approach. This approach had to be adapted to the case at hand in order to deal with problems such as the geometric weakness inherent to calibration baselines and scale uncertainty derived from both the use of different instruments and the high correlation between the meteorological correction and scale determination. Additionally, the so-called the maximum number of stable points method was also tested. In this contribution it is described the process followed to assess the stability of the UPV submillimetric calibration baseline during the period of time from 2012 to 2015.

  6. Back pain in seniors: the Back pain Outcomes using Longitudinal Data (BOLD) cohort baseline data.

    PubMed

    Jarvik, Jeffrey G; Comstock, Bryan A; Heagerty, Patrick J; Turner, Judith A; Sullivan, Sean D; Shi, Xu; Nerenz, David R; Nedeljkovic, Srdjan S; Kessler, Larry; James, Kathryn; Friedly, Janna L; Bresnahan, Brian W; Bauer, Zoya; Avins, Andrew L; Deyo, Richard A

    2014-04-23

    Back pain represents a substantial burden globally, ranking first in a recent assessment among causes of years lived with disability. Though back pain is widely studied among working age adults, there are gaps with respect to basic descriptive epidemiology among seniors, especially in the United States. Our goal was to describe how pain, function and health-related quality of life vary by demographic and geographic factors among seniors presenting to primary care providers with new episodes of care for back pain. We examined baseline data from the Back pain Outcomes using Longitudinal Data (BOLD) registry, the largest inception cohort to date of seniors presenting to a primary care provider for back pain. The sample included 5,239 patients ≥ 65 years old with a new primary care visit for back pain at three integrated health systems (Northern California Kaiser-Permanente, Henry Ford Health System [Detroit], and Harvard Vanguard Medical Associates [Boston]). We examined differences in patient characteristics across healthcare sites and associations of patient sociodemographic and clinical characteristics with baseline patient-reported measures of pain, function, and health-related quality of life. Patients differed across sites in demographic and other characteristics. The Detroit site had more African-American patients (50%) compared with the other sites (7-8%). The Boston site had more college graduates (68%) compared with Detroit (20%). Female sex, lower educational status, African-American race, and older age were associated with worse functional disability as measured by the Roland-Morris Disability Questionnaire. Except for age, these factors were also associated with worse pain. Baseline pain and functional impairment varied substantially with a number of factors in the BOLD cohort. Healthcare site was an important factor. After controlling for healthcare site, lower education, female sex, African-American race, and older age were associated with worse

  7. A Fully Customized Baseline Removal Framework for Spectroscopic Applications.

    PubMed

    Giguere, Stephen; Boucher, Thomas; Carey, C J; Mahadevan, Sridhar; Dyar, M Darby

    2017-07-01

    The task of proper baseline or continuum removal is common to nearly all types of spectroscopy. Its goal is to remove any portion of a signal that is irrelevant to features of interest while preserving any predictive information. Despite the importance of baseline removal, median or guessed default parameters are commonly employed, often using commercially available software supplied with instruments. Several published baseline removal algorithms have been shown to be useful for particular spectroscopic applications but their generalizability is ambiguous. The new Custom Baseline Removal (Custom BLR) method presented here generalizes the problem of baseline removal by combining operations from previously proposed methods to synthesize new correction algorithms. It creates novel methods for each technique, application, and training set, discovering new algorithms that maximize the predictive accuracy of the resulting spectroscopic models. In most cases, these learned methods either match or improve on the performance of the best alternative. Examples of these advantages are shown for three different scenarios: quantification of components in near-infrared spectra of corn and laser-induced breakdown spectroscopy data of rocks, and classification/matching of minerals using Raman spectroscopy. Software to implement this optimization is available from the authors. By removing subjectivity from this commonly encountered task, Custom BLR is a significant step toward completely automatic and general baseline removal in spectroscopic and other applications.

  8. High Baseline Postconcussion Symptom Scores and Concussion Outcomes in Athletes.

    PubMed

    Custer, Aimee; Sufrinko, Alicia; Elbin, R J; Covassin, Tracey; Collins, Micky; Kontos, Anthony

    2016-02-01

    Some healthy athletes report high levels of baseline concussion symptoms, which may be attributable to several factors (eg, illness, personality, somaticizing). However, the role of baseline symptoms in outcomes after sport-related concussion (SRC) has not been empirically examined. To determine if athletes with high symptom scores at baseline performed worse than athletes without baseline symptoms on neurocognitive testing after SRC. Cohort study. High school and collegiate athletic programs. A total of 670 high school and collegiate athletes participated in the study. Participants were divided into groups with either no baseline symptoms (Postconcussion Symptom Scale [PCSS] score = 0, n = 247) or a high level of baseline symptoms (PCSS score > 18 [top 10% of sample], n = 68). Participants were evaluated at baseline and 2 to 7 days after SRC with the Immediate Post-concussion Assessment and Cognitive Test and PCSS. Outcome measures were Immediate Post-concussion Assessment and Cognitive Test composite scores (verbal memory, visual memory, visual motor processing speed, and reaction time) and total symptom score on the PCSS. The groups were compared using repeated-measures analyses of variance with Bonferroni correction to assess interactions between group and time for symptoms and neurocognitive impairment. The no-symptoms group represented 38% of the original sample, whereas the high-symptoms group represented 11% of the sample. The high-symptoms group experienced a larger decline from preinjury to postinjury than the no-symptoms group in verbal (P = .03) and visual memory (P = .05). However, total concussion-symptom scores increased from preinjury to postinjury for the no-symptoms group (P = .001) but remained stable for the high-symptoms group. Reported baseline symptoms may help identify athletes at risk for worse outcomes after SRC. Clinicians should examine baseline symptom levels to better identify patients for earlier referral and treatment for their

  9. High Baseline Postconcussion Symptom Scores and Concussion Outcomes in Athletes

    PubMed Central

    Custer, Aimee; Sufrinko, Alicia; Elbin, R. J.; Covassin, Tracey; Collins, Micky; Kontos, Anthony

    2016-01-01

    Context:  Some healthy athletes report high levels of baseline concussion symptoms, which may be attributable to several factors (eg, illness, personality, somaticizing). However, the role of baseline symptoms in outcomes after sport-related concussion (SRC) has not been empirically examined. Objective:  To determine if athletes with high symptom scores at baseline performed worse than athletes without baseline symptoms on neurocognitive testing after SRC. Design:  Cohort study. Setting:  High school and collegiate athletic programs. Patients or Other Participants:  A total of 670 high school and collegiate athletes participated in the study. Participants were divided into groups with either no baseline symptoms (Postconcussion Symptom Scale [PCSS] score = 0, n = 247) or a high level of baseline symptoms (PCSS score > 18 [top 10% of sample], n = 68). Main Outcome Measure(s):  Participants were evaluated at baseline and 2 to 7 days after SRC with the Immediate Post-concussion Assessment and Cognitive Test and PCSS. Outcome measures were Immediate Post-concussion Assessment and Cognitive Test composite scores (verbal memory, visual memory, visual motor processing speed, and reaction time) and total symptom score on the PCSS. The groups were compared using repeated-measures analyses of variance with Bonferroni correction to assess interactions between group and time for symptoms and neurocognitive impairment. Results:  The no-symptoms group represented 38% of the original sample, whereas the high-symptoms group represented 11% of the sample. The high-symptoms group experienced a larger decline from preinjury to postinjury than the no-symptoms group in verbal (P = .03) and visual memory (P = .05). However, total concussion-symptom scores increased from preinjury to postinjury for the no-symptoms group (P = .001) but remained stable for the high-symptoms group. Conclusions:>  Reported baseline symptoms may help identify athletes at risk for worse

  10. Baselining Young People's Literacy in Middlesbrough in 2012

    ERIC Educational Resources Information Center

    Clark, Christina

    2013-01-01

    This report presents baseline information about the degree to which children and young people in Middlesbrough enjoy reading and writing, how often then engage in reading and writing, what types of materials they read and write and how they feel about reading and writing. It also outlines baseline information about their confidence in their own…

  11. Baseline Removal From EMG Recordings

    DTIC Science & Technology

    2001-10-25

    a time-varying baseline contamination. Acknowledgements: Work funded by the Departamento de Salud del Gobierno de Navarrra and by a Spanish MEC...Name(s) and Address(es) Departamento de Ingenieria Electra y Electronica Universidad Publica de Navarra Pamplona, Spain Performing Organization Report

  12. 49 CFR Appendix C to Part 227 - Audiometric Baseline Revision

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... FRA STS. The two ears are examined separately and independently for improvement and for worsening. If one ear meets the criteria for revision of baseline, then the baseline is revised for that ear only. Therefore, if the two ears show different hearing trends, the baseline for the left ear may be from one test...

  13. 49 CFR Appendix C to Part 227 - Audiometric Baseline Revision

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... FRA STS. The two ears are examined separately and independently for improvement and for worsening. If one ear meets the criteria for revision of baseline, then the baseline is revised for that ear only. Therefore, if the two ears show different hearing trends, the baseline for the left ear may be from one test...

  14. 49 CFR Appendix C to Part 227 - Audiometric Baseline Revision

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... the hearing conservation program. If no appropriate pre-entry audiogram exists, the baseline is the.... Therefore, if the two ears show different hearing trends, the baseline for the left ear may be from one test date, while the baseline for the right ear may be from a different test date. E. Age corrections do not...

  15. Validity and Reliability of Baseline Testing in a Standardized Environment.

    PubMed

    Higgins, Kathryn L; Caze, Todd; Maerlender, Arthur

    2017-08-11

    The Immediate Postconcussion Assessment and Cognitive Testing (ImPACT) is a computerized neuropsychological test battery commonly used to determine cognitive recovery from concussion based on comparing post-injury scores to baseline scores. This model is based on the premise that ImPACT baseline test scores are a valid and reliable measure of optimal cognitive function at baseline. Growing evidence suggests that this premise may not be accurate and a large contributor to invalid and unreliable baseline test scores may be the protocol and environment in which baseline tests are administered. This study examined the effects of a standardized environment and administration protocol on the reliability and performance validity of athletes' baseline test scores on ImPACT by comparing scores obtained in two different group-testing settings. Three hundred-sixty one Division 1 cohort-matched collegiate athletes' baseline data were assessed using a variety of indicators of potential performance invalidity; internal reliability was also examined. Thirty-one to thirty-nine percent of the baseline cases had at least one indicator of low performance validity, but there were no significant differences in validity indicators based on environment in which the testing was conducted. Internal consistency reliability scores were in the acceptable to good range, with no significant differences between administration conditions. These results suggest that athletes may be reliably performing at levels lower than their best effort would produce. © The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  16. Factors Influencing Depression Endpoints Research (FINDER): baseline results of Italian patients with depression

    PubMed Central

    Grassi, Luigi; Rossi, Andrea; Barraco, Alessandra

    2009-01-01

    Background Factors Influencing Depression Endpoints Research (FINDER) is a 6-month, prospective, observational study carried out in 12 European countries aimed at investigating health-related quality of life (HRQoL) in outpatients receiving pharmacological treatment for a first or new depressive episode. Baseline characteristics of patients enrolled in Italy are presented. Methods All treatment decisions were at the discretion of the investigator. Data were collected at baseline and after 3 and 6 months of treatment. Baseline evaluations included demographics, medical and psychiatric history, and medications used in the last 24 months and prescribed at enrolment. The Hospital Anxiety and Depression Scale (HADS), was adopted to evaluate depressive symptoms, while somatic and painful physical symptoms were assessed by using the Somatic Symptom Inventory (SSI) and a 0 to 100 mm visual analogue scale (VAS), HRQoL via 36-item Short Form Health Survey (SF-36), and the European Quality of Life 5-Dimensions (EQ-5D) instrument. Results A total of 513 patients were recruited across 38 sites. The mean ± standard deviation (SD) age at first depressive episode was 38.7 ± 15.9 years, the mean duration of depression 10.6 ± 12.3 years. The most common psychiatric comorbidities in the previous 24 months were anxiety/panic (72.6%) and obsessive/compulsive disorders (13.4%), while 35.9% had functional somatic syndromes. Most patients (65.1%) reported pain from any cause. Monotherapy with selective serotonin reuptake inhibitors (SSRIs) and tricyclic antidepressants (TCAs) was prescribed at enrolment in 64.5% and 6.4% of the cases, respectively. The most commonly prescribed agents were sertraline (17.3%), escitalopram (16.2%), venlaflaxine (15.6%) and paroxetine (14.8%). The mean HADS subscores for depression and anxiety were 13.3 ± 4.2 and 12.2 ± 3.9, respectively; 76.4% of patients could be defined as being 'probable cases' for depression and 66.2% for anxiety. The mean total

  17. Overseas Environmental Baseline Guidance Document

    DTIC Science & Technology

    2007-05-01

    The primary purpose of this Overseas Environmental Baseline Guidance Document (OEBGD) is to provide criteria and management practices to be used by ...establishes standards for environmental compliance at Department of Defense controlled or operated installations in countries for which no FGS have been established.

  18. Health-related quality of life, work productivity, and health care resource utilization of subjects with irritable bowel syndrome: baseline results from LOGIC (Longitudinal Outcomes Study of Gastrointestinal Symptoms in Canada), a naturalistic study.

    PubMed

    Paré, Pierre; Gray, James; Lam, Sy; Balshaw, Robert; Khorasheh, Shideh; Barbeau, Martin; Kelly, Suzanne; McBurney, Christopher R

    2006-10-01

    Abdominal pain/discomfort, bloating, and constipation are gastrointestinal dysmotility and sensory symptoms associated with irritable bowel syndrome (IBS). No studies have followed patients with IBS symptoms for 1 year under conditions of routine clinical practice to assess prospectively the impact of treatments on health outcomes. The objective of this ongoing, naturalistic study is to assess the long-term impact of IBS treatments on quality of life (QOL), work productivity, and resource utilization. This report describes the baseline characteristics and patterns of care of the patients enrolled in this study. Patients with physician-diagnosed IBS symptoms were enrolled from 147 physician sites across Canada between May 4, 2004, and March 31, 2005. Clinical data were collected at baseline and at the end of the 12-month follow-up (patients were followed for 1 year between May 4, 2005, and March 31, 2006). Patient-reported outcomes were collected at baseline and at months 1, 2, 6, 9, and 12. Health-related QOL, health status, and work productivity were assessed with the IBS-QOL, a 5-item EuroQol descriptive system, and Work Productivity and Activity Impairment questionnaires, respectively. A resource utilization questionnaire elicited information on physician; visits, treatments, and procedures. Baseline data are reported here. Data were obtained from 1555 patients; 85.1% (1320/1552) were women. Patients had a mean (SD) age of 45.8 (15.0) years and mean (SD) duration of IBS symptoms of 11.4 (11.5) years. Self-reported bowel patterns were predominantly constipation (41.0%, 587/1433) and constipation alternating with diarrhea (39.4%, 564/1433); 60.3% (938/1555) of subjects used > or =3 IBS treatments in the previous 4 weeks. Approximately 50% of all patients reported distress "quite a bit or "extremely" for abdominal pain, gas, bloating, and constipation. The mean overall IBS-QOL score (0-100 scale, with 0 indicating poor QOL) was 66.3; food avoidance (51.8) and

  19. Impact of Advanced Practice Registered Nurses on Quality Measures: The Missouri Quality Initiative Experience.

    PubMed

    Rantz, Marilyn J; Popejoy, Lori; Vogelsmeier, Amy; Galambos, Colleen; Alexander, Greg; Flesner, Marcia; Murray, Cathy; Crecelius, Charles; Ge, Bin; Petroski, Gregory

    2018-06-01

    The purpose of this article is to review the impact of advanced practice registered nurses (APRNs) on the quality measure (QM) scores of the 16 participating nursing homes of the Missouri Quality Initiative (MOQI) intervention. The MOQI was one of 7 program sites in the US, with specific interventions unique to each site tested for the Centers for Medicaid and Medicare Services Innovations Center. While the goals of the MOQI for long-stay nursing home residents did not specifically include improvement of the QM scores, it was anticipated that improvement most likely would occur. Primary goals of the MOQI were to reduce the frequency of avoidable hospital admissions and readmissions; improve resident health outcomes; improve the process of transitioning between inpatient hospitals and nursing facilities; and reduce overall healthcare spending without restricting access to care or choice of providers. A 2-group comparison analysis was conducted using statewide QMs; a matched comparison group was selected from facilities in the same counties as the intervention homes, similar baseline QM scores, similar size and ownership. MOQI nursing homes each had an APRN embedded full-time to improve care and help the facility achieve MOQI goals. Part of their clinical work with residents and staff was to focus on quality improvement strategies with potential to influence healthcare outcomes. Trajectories of QM scores for the MOQI intervention nursing homes and matched comparison group homes were tested with nonparametric tests to examine for change in the desired direction between the 2 groups from baseline to 36 months. A composite QM score for each facility was constructed, and baseline to 36-month average change scores were examined using nonparametric tests. Then, adjusting for baseline, a repeated measures analysis using analysis of covariance as conducted. Composite QM scores of the APRN intervention group were significantly better (P = .025) than the comparison group

  20. Placental baseline conditions modulate the hyperoxic BOLD-MRI response.

    PubMed

    Sinding, Marianne; Peters, David A; Poulsen, Sofie S; Frøkjær, Jens B; Christiansen, Ole B; Petersen, Astrid; Uldbjerg, Niels; Sørensen, Anne

    2018-01-01

    Human pregnancies complicated by placental dysfunction may be characterized by a high hyperoxic Blood oxygen level-dependent (BOLD) MRI response. The pathophysiology behind this phenomenon remains to be established. The aim of this study was to evaluate whether it is associated with altered placental baseline conditions, including a lower oxygenation and altered tissue morphology, as estimated by the placental transverse relaxation time (T2*). We included 49 normal pregnancies (controls) and 13 pregnancies complicated by placental dysfunction (cases), defined by a birth weight < 10th percentile in combination with placental pathological signs of vascular malperfusion. During maternal oxygen inhalation, we measured the relative ΔBOLD response ((hyperoxic BOLD - baseline BOLD)/baseline BOLD) from a dynamic single-echo gradient-recalled echo (GRE) MRI sequence and the absolute ΔT2* (hyperoxic T2*- baseline T2*) from breath-hold multi-echo GRE sequences. In the control group, the relative ΔBOLD response increased during gestation from 5% in gestational week 20 to 20% in week 40. In the case group, the relative ΔBOLD response was significantly higher (mean Z-score 4.94; 95% CI 2.41, 7.47). The absolute ΔT2*, however, did not differ between controls and cases (p = 0.37), whereas the baseline T2* was lower among cases (mean Z-score -3.13; 95% CI -3.94, -2.32). Furthermore, we demonstrated a strong negative linear correlation between the Log 10 ΔBOLD response and the baseline T2* (r = -0.88, p < 0.0001). The high hyperoxic ΔBOLD response demonstrated in pregnancies complicated by placental dysfunction may simply reflect altered baseline conditions, as the absolute increase in placental oxygenation (ΔT2*) does not differ between groups. Copyright © 2017 Elsevier Ltd. All rights reserved.

  1. The effect of singing training on voice quality for people with quadriplegia.

    PubMed

    Tamplin, Jeanette; Baker, Felicity A; Buttifant, Mary; Berlowitz, David J

    2014-01-01

    Despite anecdotal reports of voice impairment in quadriplegia, the exact nature of these impairments is not well described in the literature. This article details objective and subjective voice assessments for people with quadriplegia at baseline and after a respiratory-targeted singing intervention. Randomized controlled trial. Twenty-four participants with quadriplegia were randomly assigned to a 12-week program of either a singing intervention or active music therapy control. Recordings of singing and speech were made at baseline, 6 weeks, 12 weeks, and 6 months postintervention. These deidentified recordings were used to measure sound pressure levels and assess voice quality using the Multidimensional Voice Profile and the Perceptual Voice Profile. Baseline voice quality data indicated deviation from normality in the areas of breathiness, strain, and roughness. A greater percentage of intervention participants moved toward more normal voice quality in terms of jitter, shimmer, and noise-to-harmonic ratio; however, the improvements failed to achieve statistical significance. Subjective and objective assessments of voice quality indicate that quadriplegia may have a detrimental effect on voice quality; in particular, causing a perception of roughness and breathiness in the voice. The results of this study suggest that singing training may have a role in ameliorating these voice impairments. Copyright © 2014 The Voice Foundation. Published by Mosby, Inc. All rights reserved.

  2. Evaluation of the ride quality of a light twin engine airplane using a ride quality meter

    NASA Technical Reports Server (NTRS)

    Stewart, Eric C.

    1989-01-01

    A ride quality meter was used to establish the baseline ride quality of a light twin-engine airplane planned for use as a test bed for an experimental gust alleviation system. The ride quality meter provides estimates of passenger ride discomfort as a function of cabin noise and vibration (acceleration) in five axes (yaw axis omitted). According to the ride quality meter, in smooth air the cabin noise was the dominant source of passenger discomfort, but the total discomfort was approximately the same as that for the smooth-air condition. The researcher's subjective opinion, however, is that the total ride discomfort was much worse in the moderate turbulence than it was in the smooth air. The discrepancy is explained by the lack of measurement of the low-frequency accelerations by the ride quality meter.

  3. Dynamic baseline detection method for power data network service

    NASA Astrophysics Data System (ADS)

    Chen, Wei

    2017-08-01

    This paper proposes a dynamic baseline Traffic detection Method which is based on the historical traffic data for the Power data network. The method uses Cisco's NetFlow acquisition tool to collect the original historical traffic data from network element at fixed intervals. This method uses three dimensions information including the communication port, time, traffic (number of bytes or number of packets) t. By filtering, removing the deviation value, calculating the dynamic baseline value, comparing the actual value with the baseline value, the method can detect whether the current network traffic is abnormal.

  4. Water quality at a biosolids-application area near Deer Trail, Colorado, 1993-1999

    USGS Publications Warehouse

    Yager, Tracy J.B.

    2014-01-01

    The Metro Wastewater Reclamation District (Metro District) in Denver, Colo., applied biosolids resulting from municipal sewage treatment to farmland in eastern Colorado beginning in December 1993. In mid-1993, the U.S. Geological Survey in cooperation with the Metro District began monitoring water quality at the biosolids-application area about 10 miles east of Deer Trail, Colo., to evaluate baseline water quality and the combined effects of natural processes, land uses, and biosolids applications on water quality of the biosolids application area. Water quality was characterized by baseline and post-biosolids-application sampling for selected inorganic and bacteriological constituents during 1993 through 1998, with some additional specialized sampling in 1999. The study included limited sampling of surface water and the unsaturated zone, but primarily focused on groundwater. See report for complete abstract.

  5. Forecasting Sensorimotor Adaptability from Baseline Inter-Trial Correlations

    NASA Technical Reports Server (NTRS)

    Beaton, K. H.; Bloomberg, J. J.

    2014-01-01

    One of the greatest challenges surrounding adaptation to the spaceflight environment is the large variability in symptoms, and corresponding functional impairments, from one crewmember to the next. This renders preflight training and countermeasure development difficult, as a "one-size-fits-all" approach is inappropriate. Therefore, it would be highly advantageous to know ahead of time which crewmembers might have more difficulty adjusting to the novel g-levels inherent to spaceflight. Such knowledge could guide individually customized countermeasures, which would enable more efficient use of crew time, both preflight and inflight, and provide better outcomes. The primary goal of this project is to look for a baseline performance metric that can forecast sensorimotor adaptability without exposure to an adaptive stimulus. We propose a novel hypothesis that considers baseline inter-trial correlations, the trial-to-trial fluctuations in motor performance, as a predictor of individual sensorimotor adaptive capabilities. To-date, a strong relationship has been found between baseline inter-trial correlations and adaptability in two oculomotor systems. For this project, we will explore an analogous predictive mechanism in the locomotion system. METHODS: Baseline Inter-trial Correlations: Inter-trial correlations specify the relationships among repeated trials of a given task that transpire as a consequence of correcting for previous performance errors over multiple timescales. We can quantify the strength of inter-trial correlations by measuring the decay of the autocorrelation function (ACF), which describes how rapidly information from past trials is "forgotten." Processes whose ACFs decay more slowly exhibit longer-term inter-trial correlations (longer memory processes), while processes whose ACFs decay more rapidly exhibit shorterterm inter-trial correlations (shorter memory processes). Longer-term correlations reflect low-frequency activity, which is more easily

  6. Defining the baseline for inhibition concentration calculations for hormetic hazards.

    PubMed

    Bailer, A J; Oris, J T

    2000-01-01

    The use of endpoint estimates based on modeling inhibition of test organism response relative to a baseline response is an important tool in the testing and evaluation of aquatic hazards. In the presence of a hormetic hazard, the definition of the baseline response is not clear because non-zero levels of the hazard stimulate an enhanced response prior to inhibition. In the present study, the methodology and implications of how one defines a baseline response for inhibition concentration estimation in aquatic toxicity tests was evaluated. Three possible baselines were considered: the control response level; the pooling of responses, including controls and all concentration conditions with responses enhanced relative to controls; and, finally, the maximal response. The statistical methods associated with estimating inhibition relative to the first two baseline definitions were described and a method for estimating inhibition relative to the third baseline definition was derived. These methods were illustrated with data from a standard aquatic zooplankton reproductive toxicity test in which the number of young produced in three broods of a cladoceran exposed to effluent was modeled as a function of effluent concentration. Copyright 2000 John Wiley & Sons, Ltd.

  7. THE FIRST VERY LONG BASELINE INTERFEROMETRIC SETI EXPERIMENT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rampadarath, H.; Morgan, J. S.; Tingay, S. J.

    2012-08-15

    The first Search for Extra-Terrestrial Intelligence (SETI) conducted with very long baseline interferometry (VLBI) is presented. By consideration of the basic principles of interferometry, we show that VLBI is efficient at discriminating between SETI signals and human generated radio frequency interference (RFI). The target for this study was the star Gliese 581, thought to have two planets within its habitable zone. On 2007 June 19, Gliese 581 was observed for 8 hr at 1230-1544 MHz with the Australian Long Baseline Array. The data set was searched for signals appearing on all interferometer baselines above five times the noise limit. Amore » total of 222 potential SETI signals were detected and by using automated data analysis techniques were ruled out as originating from the Gliese 581 system. From our results we place an upper limit of 7 MW Hz{sup -1} on the power output of any isotropic emitter located in the Gliese 581 system within this frequency range. This study shows that VLBI is ideal for targeted SETI including follow-up observations. The techniques presented are equally applicable to next-generation interferometers, such as the long baselines of the Square Kilometre Array.« less

  8. The Pittsburgh Sleep Quality Index: validation of the Urdu translation.

    PubMed

    Hashmi, Ali Madeeh; Khawaja, Imran Shuja; Butt, Zeeshan; Umair, Muhammad; Naqvi, Suhaib Haider; Jawad-Ul-Haq

    2014-02-01

    To translate and validate the Pittsburgh Sleep Quality Index (PSQI), a standardized self-administered questionnaire for the assessment of subjective sleep quality into the Urdu language. Validation study. Mayo Hospital, Lahore, from March to April 2012. The PSQI was translated into Urdu following standard guidelines. The final Urdu version (PSQI-U) was administered to 200 healthy volunteers comprising medical students, nursing staff and doctors. Inter-item correlation was assessed by calculating Cronbach alpha. Correlation of component scores with global score was assessed by calculating Spearman correlation coefficient. Correlation between global PSQI-U scores at baseline with global scores for each PSQI-U and PSQI-E at 4-week interval was evaluated by calculating Spearman correlation coefficient. Moreover, scores on individual items of the scale at baseline were compared with respective scores after 4-week by t-test. One hundred and eighty five (185) participants completed the PSQI-U at baseline. The Cronbach alpha for PSQI-U was 0.56. Scores on individual components of the PSQI-U and composite scores were all highly correlated with each other (all p-values < 0.01). Composite scores for PSQI-U at baseline and PSQI-E at 4-week interval were also highly correlated with each other (Spearman correlation coefficient 0.74, p-value < 0.01) indicating good linguistic interchangeability. Composite scores for PSQI-U at baseline and at 4-week interval were positively correlated with each other (Spearman correlation coefficient 0.70, p < 0.01) indicating good test-retest reliability. The PSQI-U is a valid and reliable instrument for the assessment of sleep quality. It shows good linguistic interchangeability and test-retest reliability in comparison to the original English version when applied to individuals who speak the Urdu language. The PSQI-U can be a tool either for clinical management or research.

  9. Questa Baseline and Pre-Mining Ground-Water Quality Investigation. 1. Depth to Bedrock Determinations Using Shallow Seismic Data Acquired in the Straight Creek Drainage Near Red River, New Mexico

    USGS Publications Warehouse

    Powers, Michael H.; Burton, Bethany L.

    2004-01-01

    In late May and early June of 2002, the U.S. Geological Survey (USGS) acquired four P-wave seismic profiles across the Straight Creek drainage near Red River, New Mexico. The data were acquired to support a larger effort to investigate baseline and pre-mining ground-water quality in the Red River basin (Nordstrom and others, 2002). For ground-water flow modeling, knowledge of the thickness of the valley fill material above the bedrock is required. When curved-ray refraction tomography was used with the seismic first arrival times, the resulting images of interval velocity versus depth clearly show a sharp velocity contrast where the bedrock interface is expected. The images show that the interpreted buried bedrock surface is neither smooth nor sharp, but it is clearly defined across the valley along the seismic line profiles. The bedrock models defined by the seismic refraction images are consistent with the well data.

  10. Baseline Equivalence. WWC Standards Brief

    ERIC Educational Resources Information Center

    What Works Clearinghouse, 2017

    2017-01-01

    The What Works Clearinghouse (WWC) uses the term "baseline equivalence" when determining if the intervention group (those that received the intervention of interest) and the comparison group (those that did not receive the intervention) had characteristics that were similar enough ("equivalent") at the start of the study (at…

  11. Display system replacement baseline research report.

    DOT National Transportation Integrated Search

    2000-12-01

    This report provides baseline measurements on the Display System Replacement (DSR). These measurements followed six constructs: : safety, capacity, performance, workload, usability, and simulation fidelity. To collect these measurements, human factor...

  12. Responsive parenting is associated with improved type 1 diabetes-related quality of life

    PubMed Central

    Botello-Harbaum, Maria; Nansel, Tonja; Haynie, Denise; Iannotti, Ronald J.; Simons-Morton, Bruce

    2008-01-01

    Background Improved quality of life is an important treatment goal for children and adolescents with type 1 diabetes. While previous research supports a relationship between family environment and quality of life, little research has addressed the relationship of parenting style constructs to quality of life in children with chronic disease. The present investigation assesses the relationship of parent responsiveness and demandingness with diabetes-related quality of life among children and adolescents with type 1 diabetes. Methods Baseline and 12-month follow-up self-report assessments were collected on a sample of 81 children with type 1 diabetes participating in an efficacy trial of a behavioral intervention to enhance adherence. The sample had a mean age of 13.3 years (SD = 1.7) and duration of diabetes of 7.7 years (SD = 3.7). Multiple regression analyses were conducted to determine the relationship of parent responsiveness and demandingness to diabetes-related quality of life at each time point. Results After adjusting for demographic and diabetes characteristics, as well as diabetes-specific parent-child behaviors, parent responsiveness was significantly associated with baseline diabetes-related quality of life (B=.23; p=.04). This relationship was sustained at 12-month follow-up (B=.22; p=.04) after adjusting for baseline quality of life and treatment group assignment, suggesting that parent responsiveness is associated with improved quality of life. Conclusions Findings indicate the importance of a supportive and emotionally warm parenting style in promoting improved quality of life for children with type 1 diabetes. Appropriate parenting skills should be an element of diabetes family management health care. PMID:18796059

  13. Effect of baseline corrections on displacements and response spectra for several recordings of the 1999 Chi-Chi, Taiwan, earthquake

    USGS Publications Warehouse

    Boore, D.M.

    2001-01-01

    Displacements derived from many of the accelerogram recordings of the 1999 Chi-Chi, Taiwan, earthquake show drifts when only a simple baseline derived from the pre-event portion of the record is removed from the records. The appearance of the velocity and displacement records suggests that changes in the zero level of the acceleration are responsible for these drifts. The source of the shifts in zero level are unknown, but in at least one case it is almost certainly due to tilting of the ground. This article illustrates the effect on the ground velocity, ground displacement, and response spectra of several schemes for accounting for these baseline shifts. A wide range of final displacements can be obtained for various choices of baseline correction, and comparison with nearby GPS stations (none of which are colocated with the accelerograph stations) do not help in choosing the appropriate baseline correction. The results suggest that final displacements estimated from the records should be used with caution. The most important conclusion for earthquake engineering purposes, however, is that the response spectra for periods less than about 20 sec are usually unaffected by the baseline correction. Although limited to the analysis of only a small number of recordings, the results may have more general significance both for the many other recordings of this earthquake and for data that will be obtained in the future from similar high-quality accelerograph networks now being installed or soon to be installed in many parts of the world.

  14. Perception and predictors of quality of life among HIV patients attending art clinics in northwest Ethiopia: a prospective longitudinal study.

    PubMed

    Wubshet, Mamo; Berhane, Yemane; Worku, Alemayehu; Kebede, Yigzaw

    2014-07-01

    In treating HIV as a chronic disease, monitoring changes of quality of life of patient's overtime is important for clinicians and policy makers. However, to our knowledge little research attention has been directed towards examining the longitudinal change of quality of life overtime in sub-Saharan Africa. To examine longitudinal changes in quality of life among patients initiated ART METHOD: A prospective longitudinal follow-up study was conducted from December 2009 to August 2011 to evaluate the changes in quality of life and how this relates with baseline socio-demographic and clinical characteristics among consecutive adult ART naïve patients attending ART clinic. Quality of life was measured by WHOQOL-HIV BREF. All quality of life domain scores improved significantly during 12 month follow-up in the ART program. At each follow-up visit, scores were significantly higher than baseline scores (p < 0.001). Predictors of improved quality of life were male gender, disclosure of HIV status, starting ART at higher CD4, > 200 cells/μL, and good baseline overall quality of life, whereas predictors of poor quality of life were starting ART with advanced disease stage and tuberculosis co-infection. This study demonstrated that the quality of life improved overtime for HIV-infected individuals receiving ART which is consistent with previous studies. It also provided information regarding the predictive effects of baseline socio-demographic and clinical factors on the changes in quality of life at the 12-month follow-up time. The finding of the study has implications of starting ART at a higher CD4 and early stage of the disease for better quality of life outcomes.

  15. Atmospheric refraction effects on baseline error in satellite laser ranging systems

    NASA Technical Reports Server (NTRS)

    Im, K. E.; Gardner, C. S.

    1982-01-01

    Because of the mathematical complexities involved in exact analyses of baseline errors, it is not easy to isolate atmospheric refraction effects; however, by making certain simplifying assumptions about the ranging system geometry, relatively simple expressions can be derived which relate the baseline errors directly to the refraction errors. The results indicate that even in the absence of other errors, the baseline error for intercontinental baselines can be more than an order of magnitude larger than the refraction error.

  16. The dead do not lie: using skeletal remains for rapid assessment of historical small-mammal community baselines

    PubMed Central

    Terry, Rebecca C.

    2010-01-01

    Conservation and restoration efforts are often hindered by a lack of historical baselines that pre-date intense anthropogenic environmental change. In this paper I document that natural accumulations of skeletal remains represent a potential source of high-quality data on the historical composition and structure of small-mammal communities. I do so by assessing the fidelity of modern, decadal and centennial-scale time-averaged samples of skeletal remains (concentrated by raptor predation) to the living small-mammal communities from which they are derived. To test the power of skeletal remains to reveal baseline shifts, I employ the design of a natural experiment, comparing two taphonomically similar Great Basin cave localities in areas where anthropogenic land-use practices have diverged within the last century. I find relative stasis at the undisturbed site, but document rapid restructuring of the small-mammal community at the site subjected to recent disturbance. I independently validate this result using historical trapping records to show that dead remains accurately capture both the magnitude and direction of this baseline shift. Surveys of skeletal remains therefore provide a simple, powerful and rapid alternative approach for gaining insight into the historical structure and dynamics of modern small-mammal communities. PMID:20031992

  17. Effect of baseline corrections on response spectra for two recordings of the 1999 Chi-Chi, Taiwan, earthquake

    USGS Publications Warehouse

    Boore, David M.

    1999-01-01

    Displacements derived from the accelerogram recordings of the 1999 Chi-Chi, Taiwan earthquake at stations TCU078 and TCU129 show drifts when only a simple baseline derived from the pre-event portion of the record is removed from the records. The appearance of the velocity and displacement records suggests that changes in the zero-level of the acceleration are responsible for these drifts. The source of the shifts in zero-level are unknown, but might include tilts in the instruments or the response of the instruments to strong shaking. This note illustrates the effect on the velocity, displacement, and response spectra of several schemes for accounting for these baseline shifts. The most important conclusion for earthquake engineering purposes is that the response spectra for periods less than about 20 sec are unaffected by the baseline correction. The results suggest, however, that staticdisplac ements estimated from the instruments should be used with caution. Although limited to the analysis of only two recordings, the results may have more general significance both for the many other recordings of this earthquake and for data that will be obtained in the future from similar high-quality accelerograph networks now being installed or soon to be installed in many parts of the world.

  18. A baseline-free procedure for transformation models under interval censorship.

    PubMed

    Gu, Ming Gao; Sun, Liuquan; Zuo, Guoxin

    2005-12-01

    An important property of Cox regression model is that the estimation of regression parameters using the partial likelihood procedure does not depend on its baseline survival function. We call such a procedure baseline-free. Using marginal likelihood, we show that an baseline-free procedure can be derived for a class of general transformation models under interval censoring framework. The baseline-free procedure results a simplified and stable computation algorithm for some complicated and important semiparametric models, such as frailty models and heteroscedastic hazard/rank regression models, where the estimation procedures so far available involve estimation of the infinite dimensional baseline function. A detailed computational algorithm using Markov Chain Monte Carlo stochastic approximation is presented. The proposed procedure is demonstrated through extensive simulation studies, showing the validity of asymptotic consistency and normality. We also illustrate the procedure with a real data set from a study of breast cancer. A heuristic argument showing that the score function is a mean zero martingale is provided.

  19. The Emergy Baseline of the Earth: Is it Arbitrary?

    EPA Science Inventory

    The emergy baseline for the Earth is used in determining the transformities of the products of all planetary processes and through these relationships it influences all emergy evaluations. Estimates of the emergy baseline made in the past have changed depending on the number of i...

  20. Establishing effective sentinels - Setting the baseline for shale gas

    NASA Astrophysics Data System (ADS)

    Ward, C.; Worrall, F.

    2017-12-01

    The UK has a nascent shale gas industry and, unlike the US we have the opportunity to establish structures both physical and regulatory to reassure the public that any impact of a developing shale gas will be .properly licensed, regulated, monitored and, if necessary, mitigated. To assess and indeed demonstrate an impact of any activity, let alone those of shale gas exploitation, it is necessary to show, within a reasonable level of certainty, that the industry has changed a environmental state over and above that which was true without the activity present. The need for demonstrating impact not only means that a baseline needs to be established but that the baseline needs to be robustly established within a statistical and probabilistic framework so that certainty of impact can be demonstrated. A number of technologies have been proposed for monitoring the water quality impacts of shale gas developments, however, to be an effective and robust sentinel of change the parameter should have several properties: it should be a lead indicator and not a lag indicator of change; it should have a high contrast with the normal or background activity; it should show a high specificity for the activity of concern and not be associated with other activities; and it should readily deployed in time and space. By far the greatest difference between the waters arising from a shale gas well pad and surface waters is nothing more than salinity or its associated determinds. The salinity of flowback water and deep formation water can be many times greater than seawater let alone greater than the salinity of most UK surface waters. Therefore, we have built a probabilistic model of the salinity of English surface waters. We have developed a generalised linear model of the existing salinity data available for English surface waters. Generalised linear modelling means that we can use all the existing data, the approach is entirely data driven; it does not require parameterisation; and can

  1. A routine quality assurance test for CT automatic exposure control systems.

    PubMed

    Iball, Gareth R; Moore, Alexis C; Crawford, Elizabeth J

    2016-07-08

    The study purpose was to develop and validate a quality assurance test for CT automatic exposure control (AEC) systems based on a set of nested polymethylmethacrylate CTDI phantoms. The test phantom was created by offsetting the 16 cm head phantom within the 32 cm body annulus, thus creating a three part phantom. This was scanned at all acceptance, routine, and some nonroutine quality assurance visits over a period of 45 months, resulting in 115 separate AEC tests on scanners from four manufacturers. For each scan the longitudinal mA modulation pattern was generated and measurements of image noise were made in two annular regions of interest. The scanner displayed CTDIvol and DLP were also recorded. The impact of a range of AEC configurations on dose and image quality were assessed at acceptance testing. For systems that were tested more than once, the percentage of CTDIvol values exceeding 5%, 10%, and 15% deviation from baseline was 23.4%, 12.6%, and 8.1% respectively. Similarly, for the image noise data, deviations greater than 2%, 5%, and 10% from baseline were 26.5%, 5.9%, and 2%, respectively. The majority of CTDIvol and noise deviations greater than 15% and 5%, respectively, could be explained by incorrect phantom setup or protocol selection. Barring these results, CTDIvol deviations of greater than 15% from baseline were found in 0.9% of tests and noise deviations greater than 5% from baseline were found in 1% of tests. The phantom was shown to be sensitive to changes in AEC setup, including the use of 3D, longitudinal or rotational tube current modulation. This test methodology allows for continuing performance assessment of CT AEC systems, and we recommend that this test should become part of routine CT quality assurance programs. Tolerances of ± 15% for CTDIvol and ± 5% for image noise relative to baseline values should be used. © 2016 The Authors

  2. The idiopathic intracranial hypertension treatment trial: clinical profile at baseline.

    PubMed

    Wall, Michael; Kupersmith, Mark J; Kieburtz, Karl D; Corbett, James J; Feldon, Steven E; Friedman, Deborah I; Katz, David M; Keltner, John L; Schron, Eleanor B; McDermott, Michael P

    2014-06-01

    To our knowledge, there are no large prospective cohorts of untreated patients with idiopathic intracranial hypertension (IIH) to characterize the disease. To report the baseline clinical and laboratory features of patients enrolled in the Idiopathic Intracranial Hypertension Treatment Trial. We collected data at baseline from questionnaires, examinations, automated perimetry, and fundus photography grading. Patients (n = 165) were enrolled from March 17, 2010, to November 27, 2012, at 38 academic and private practice sites in North America. All participants met the modified Dandy criteria for IIH and had a perimetric mean deviation between -2 dB and -7 dB. All but 4 participants were women. Baseline and laboratory characteristics. The mean (SD) age of our patients was 29.0 (7.4) years and 4 (2.4%) were men. The average (SD) body mass index (calculated as weight in kilograms divided by height in meters squared) was 39.9 (8.3). Headache was the most common symptom (84%). Transient visual obscurations occurred in 68% of patients, back pain in 53%, and pulse synchronous tinnitus in 52%. Only 32% reported visual loss. The average (SD) perimetric mean deviation in the worst eye was -3.5 (1.1) dB, (range, -2.0 to -6.4 dB) and in the best eye was -2.3 (1.1) dB (range, -5.2 to 0.8 dB). A partial arcuate visual field defect with an enlarged blind spot was the most common perimetric finding. Visual acuity was 85 letters or better (20/20) in 71% of the worst eyes and 77% of the best eyes. Quality of life measures, including the National Eye Institute Visual Function Questionnaire-25 and the Short Form-36 physical and mental health summary scales, were lower compared with population norms. The Idiopathic Intracranial Hypertension Treatment Trial represents the largest prospectively analyzed cohort of untreated patients with IIH. Our data show that IIH is almost exclusively a disease of obese young women. Patients with IIH with mild visual loss have typical symptoms, may

  3. Very long baseline interferometry using a communication satellite

    NASA Technical Reports Server (NTRS)

    Swenson, G. W., Jr.

    1975-01-01

    A planned experiment is discussed in long-baseline interferometry, using the Communications Technology Satellite to transmit the base-band signal from one telescope to another for real-time correlation. A 20 megabit data rate is planned, calling for a delay-line of 10 MHz bandwidth and controllable delay up to 275 milliseconds. A number of sources will be studied on baselines from Ontario to West Virginia and California.

  4. Baseline automotive gas turbine engine development program

    NASA Technical Reports Server (NTRS)

    Wagner, C. E. (Editor); Pampreen, R. C. (Editor)

    1979-01-01

    Tests results on a baseline engine are presented to document the automotive gas turbine state-of-the-art at the start of the program. The performance characteristics of the engine and of a vehicle powered by this engine are defined. Component improvement concepts in the baseline engine were evaluated on engine dynamometer tests in the complete vehicle on a chassis dynamometer and on road tests. The concepts included advanced combustors, ceramic regenerators, an integrated control system, low cost turbine material, a continuously variable transmission, power-turbine-driven accessories, power augmentation, and linerless insulation in the engine housing.

  5. Urinary and sexual quality of life 1 year following robotic assisted laparoscopic radical prostatectomy.

    PubMed

    Shikanov, Sergey A; Eng, Michael K; Bernstein, Andrew J; Katz, Mark; Zagaja, Gregory P; Shalhav, Arieh L; Zorn, Kevin C

    2008-08-01

    We evaluated urinary and sexual quality of life 1 year following robotic laparoscopic radical prostatectomy and identified preoperative variables predictive of a severe decrease from baseline. Using a prospective robotic laparoscopic radical prostatectomy database we identified patients with greater than 1 year of postoperative followup. The UCLA-PCI SF-36v2 questionnaire was used to evaluate urinary and sexual quality of life before and 1 year after surgery. Severe worsening of the postoperative score was defined as a greater than 1 SD decrease. Demographic and preoperative clinical variables were evaluated along with baseline scores on univariate and multivariate analysis. Between February 2003 and September 2007 a total of 1,225 robotic laparoscopic radical prostatectomies were performed at our center and 361 patients (52%) met inclusion criteria. On multivariate analysis baseline urinary function was the only predictor of significant worsening of urinary function (OR 1.04, p = 0.003). Baseline urinary bother was the only predictor of significant worsening of urinary bother (OR 1.05, p <0.0001). A significant decrease in sexual function was predicted by baseline sexual function (OR 1.03, p = 0.0001), baseline sexual bother (OR 1.03, p = 0.005) and nerve sparing technique (OR 0.31, p = 0.05). Predictors of a significant decrease in sexual bother were also baseline sexual function (OR 1.02, p = 0.0001), baseline sexual bother (OR 1.04, p = 0.0007) and nerve sparing technique (OR 0.38, p = 0.02). ORs indicated that higher baseline scores corresponded to a higher risk of postoperative score worsening. We found that overall better baseline sexual and urinary scores are associated with better postoperative outcomes. However, the risk of a significant decrease in urinary function, urinary bother, sexual function and sexual bother is higher in patients with better baseline scores. Nerve sparing positively affects sexual function and sexual bother.

  6. Should Studies of Diabetes Treatment Stratification Correct for Baseline HbA1c?

    PubMed Central

    Jones, Angus G.; Lonergan, Mike; Henley, William E.; Pearson, Ewan R.; Hattersley, Andrew T.; Shields, Beverley M.

    2016-01-01

    Aims Baseline HbA1c is a major predictor of response to glucose lowering therapy and therefore a potential confounder in studies aiming to identify other predictors. However, baseline adjustment may introduce error if the association between baseline HbA1c and response is substantially due to measurement error and regression to the mean. We aimed to determine whether studies of predictors of response should adjust for baseline HbA1c. Methods We assessed the relationship between baseline HbA1c and glycaemic response in 257 participants treated with GLP-1R agonists and assessed whether it reflected measurement error and regression to the mean using duplicate ‘pre-baseline’ HbA1c measurements not included in the response variable. In this cohort and an additional 2659 participants treated with sulfonylureas we assessed the relationship between covariates associated with baseline HbA1c and treatment response with and without baseline adjustment, and with a bias correction using pre-baseline HbA1c to adjust for the effects of error in baseline HbA1c. Results Baseline HbA1c was a major predictor of response (R2 = 0.19,β = -0.44,p<0.001).The association between pre-baseline and response was similar suggesting the greater response at higher baseline HbA1cs is not mainly due to measurement error and subsequent regression to the mean. In unadjusted analysis in both cohorts, factors associated with baseline HbA1c were associated with response, however these associations were weak or absent after adjustment for baseline HbA1c. Bias correction did not substantially alter associations. Conclusions Adjustment for the baseline HbA1c measurement is a simple and effective way to reduce bias in studies of predictors of response to glucose lowering therapy. PMID:27050911

  7. Baselining current road weather information : results of the 2010 quality and importance survey final report.

    DOT National Transportation Integrated Search

    2011-01-30

    This final report contains research findings on the characterization of the quality and value of road weather information resources used by members of the surface transportation community in their decision-making process. This report focuses on the r...

  8. The Effect of Pretest Exercise on Baseline Computerized Neurocognitive Test Scores.

    PubMed

    Pawlukiewicz, Alec; Yengo-Kahn, Aaron M; Solomon, Gary

    2017-10-01

    Baseline neurocognitive assessment plays a critical role in return-to-play decision making following sport-related concussions. Prior studies have assessed the effect of a variety of modifying factors on neurocognitive baseline test scores. However, relatively little investigation has been conducted regarding the effect of pretest exercise on baseline testing. The aim of our investigation was to determine the effect of pretest exercise on baseline Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) scores in adolescent and young adult athletes. We hypothesized that athletes undergoing self-reported strenuous exercise within 3 hours of baseline testing would perform more poorly on neurocognitive metrics and would report a greater number of symptoms than those who had not completed such exercise. Cross-sectional study; Level of evidence, 3. The ImPACT records of 18,245 adolescent and young adult athletes were retrospectively analyzed. After application of inclusion and exclusion criteria, participants were dichotomized into groups based on a positive (n = 664) or negative (n = 6609) self-reported history of strenuous exercise within 3 hours of the baseline test. Participants with a positive history of exercise were then randomly matched, based on age, sex, education level, concussion history, and hours of sleep prior to testing, on a 1:2 basis with individuals who had reported no pretest exercise. The baseline ImPACT composite scores of the 2 groups were then compared. Significant differences were observed for the ImPACT composite scores of verbal memory, visual memory, reaction time, and impulse control as well as for the total symptom score. No significant between-group difference was detected for the visual motor composite score. Furthermore, pretest exercise was associated with a significant increase in the overall frequency of invalid test results. Our results suggest a statistically significant difference in ImPACT composite scores between

  9. 40 CFR 80.93 - Individual baseline submission and approval.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., or designee, indicating that insufficient data exist for a baseline determination by the types of...-type data is utilized. All requirements of this paragraph shall be reported separately for each... which may assist EPA in its review of the baseline; (ii) Identification of the data-type(s), per § 80.91...

  10. Baseline experiments in teleoperator control

    NASA Technical Reports Server (NTRS)

    Hankins, W. W., III; Mixon, R. W.

    1986-01-01

    Studies have been conducted at the NASA Langley Research Center (LaRC) to establish baseline human teleoperator interface data and to assess the influence of some of the interface parameters on human performance in teleoperation. As baseline data, the results will be used to assess future interface improvements resulting from this research in basic teleoperator human factors. In addition, the data have been used to validate LaRC's basic teleoperator hardware setup and to compare initial teleoperator study results. Four subjects controlled a modified industrial manipulator to perform a simple task involving both high and low precision. Two different schemes for controlling the manipulator were studied along with both direct and indirect viewing of the task. Performance of the task was measured as the length of time required to complete the task along with the number of errors made in the process. Analyses of variance were computed to determine the significance of the influences of each of the independent variables. Comparisons were also made between the LaRC data and data taken earlier by Grumman Aerospace Corp. at their facilities.

  11. The Effects of Category Generalizations and Instance Similarity on Schema Abstraction.

    DTIC Science & Technology

    1980-10-07

    reading; musical ’a-ite: classical, jazz, rock, disco, folk, country; sport: volleyball, basketball. bowling, squash, racquetball, handball . The space...Psychology 1845 Elena Ave., Fourth Floor 33 Kirkland Street Redondo Beach , CA 90277 Cambridge, MA 02138 1 Dr. Donald A Norman Mr. Marlin Kroger Dept. of...So. California Department of Computer Science Behavioral Technology Labs Rutgers University 1845 S. Elena Ave. ew Brunswick, NJ 08903 Redondo Beach

  12. The Mary Ingraham Bunting Institute of Radcliffe College.

    DTIC Science & Technology

    1992-08-31

    scientists -- biologists Elena Budrene and Doris Stern, and geologist Constance Soja -- had also been fellows during the 1990-91 fellowship year. Beginning...Balanced Cross Sections" Constance X. Soja , Geology, Harvard University "Tectonic Controls on Reef Development During the Silurian" Doris Naimark Stern...other better-situated scholars like geologists Constance Soja and Barbara Sheffels, and molecular biologists Elena Budrene and Orna Resnekov, the

  13. Baseline features and differences in 48 week clinical outcomes in patients with gastroparesis and type 1 vs type 2 diabetes.

    PubMed

    Koch, K L; Hasler, W L; Yates, K P; Parkman, H P; Pasricha, P J; Calles-Escandon, J; Snape, W J; Abell, T L; McCallum, R W; Nguyen, L A; Sarosiek, I; Farrugia, G; Tonascia, J; Lee, L; Miriel, L; Hamilton, F

    2016-07-01

    In studies of diabetic gastroparesis, patients with type 1 and type 2 diabetes mellitus (T1DM, T2DM) are often combined for analyses. We compared gastroparesis severity, healthcare utilization, psychological function, and quality of life in T1DM vs T2DM gastroparesis patients. Questionnaire, laboratory, and scintigraphy data from patients with gastroparesis and T1DM and T2DM from seven centers of the National Institute of Diabetes and Digestive and Kidney Diseases Gastroparesis Clinical Research Consortium Registry were compared at enrollment and after 48 weeks. Multiple regression models assessed baseline and follow-up differences between diabetes subtypes. At baseline, T1DM patients (N = 78) had slower gastric emptying, more hospitalizations, more gastric stimulator implantations, higher hemoglobin A1c (HbA1c), and more anxiety vs T2DM patients (N = 59). Independent discriminators of patients with T1DM vs T2DM included worse gastroesophageal reflux disease, less bloating, more peripheral neuropathy, and fewer comorbidities (p ≤ 0.05). On follow-up, gastrointestinal (GI) symptom scores decreased only in T2DM (p < 0.05), but not in T1DM patients who reported greater prokinetic, proton pump inhibitor, anxiolytic, and gastric stimulator usage over 48 weeks (p ≤ 0.03). Gastrointestinal symptoms at baseline and 48 weeks with both subtypes were not associated with HbA1c, peripheral neuropathy, psychological factors, or quality of life. Baseline symptoms were similar in T1DM and T2DM patients, even though T1DM patients had worse gastric emptying delays and higher HbA1c suggesting other factors mediate symptom severity. Symptom scores at 48 weeks decreased in T2DM, but not T1DM patients, despite increased medical and surgical treatment utilization by T1DM patients. Defining causes of different outcomes in diabetic gastroparesis warrants further investigation. © 2016 John Wiley & Sons Ltd.

  14. Influence of Baseline Psychological Health on Muscle Pain During Atorvastatin Treatment.

    PubMed

    Zaleski, Amanda L; Taylor, Beth A; Pescatello, Linda S; Dornelas, Ellen A; White, Charles Michael; Thompson, Paul D

    3-hydroxy-3-methylglutaryl coenzyme A reductase reductase inhibitors (statins) are generally well tolerated, with statin-associated muscle symptoms (SAMS) the most common side effect (~10%) seen in statin users. However, studies and clinical observations indicate that many of the self-reported SAMS appear to be nonspecific (ie, potentially not attributable to statins). Mental health and well-being influence self-perception of pain, so we sought to assess the effect of baseline well-being and depression on the development of muscle pain with 6 months of atorvastatin 80 mg/d (ATORVA) or placebo in healthy, statin-naive adults. The Psychological General Well-being Index (n = 83) and Beck Depression Inventory (n = 55) questionnaires were administered at baseline in participants (aged 59.5 ± 1.2 years) from the effect of Statins on Skeletal Muscle Function and Performance (STOMP) trial (NCT00609063). Muscle pain (Short-Form McGill Pain Questionnaire [SF-MPQ]), pain that interferes with daily life (Brief Pain Inventory [BPI]), and pain severity (BPI) were then measured before, throughout, and after treatment. At baseline, there were no differences in well-being (Psychological General Well-being Index), depression (Beck Depression Inventory), or pain measures (SF-MPQ and BPI) (P values ≥ .05) between the placebo and ATORVA groups. Baseline well-being correlated negatively with baseline BPI pain severity (r = -0.290, P = .008). Baseline depression correlated with baseline pain (SF-MPQ; r = 0.314, P = .020). Baseline well-being and depression did not predict the change in pain severity or interference after 6 months among the total sample or between groups (P values ≥ .05). Baseline well-being and depression were not significant predictors of pain after 6 months of ATORVA (P values ≥ .05). Thus, they do not appear to increase the risk of SAMS in otherwise healthy adults.

  15. The interaction between physical activity and amount of baseline knee cartilage.

    PubMed

    Teichtahl, Andrew J; Wang, Yuanyuan; Heritier, Stephane; Wluka, Anita E; Strauss, Boyd J; Proietto, Joseph; Dixon, John B; Jones, Graeme; Cicuttini, Flavia M

    2016-07-01

    Conflicting reports of the effect of physical activity on knee cartilage may be due to the heterogeneity of populations examined and, in particular, the underlying health of the knee joint. This study examined the influence of recreational and occupational physical activity on cartilage volume loss. A total of 250 participants with no significant musculoskeletal disease were recruited. A gender-specific median cartilage volume split was used to define people in the lowest and highest 50% of baseline cartilage volume. Baseline recreational and occupational activity was examined by questionnaire, while cartilage volume was assessed by MRI at baseline and 2.4 years later. Significant interactions were demonstrable between physical activity and cartilage volume loss based on stratification of baseline cartilage volume (all P ⩽ 0.03). There was a dose-response relationship between frequently performed baseline occupational activities and medial cartilage volume loss in both the low (B = 0.2% per annum, 95% CI: 0.0, 0.04% per annum) and high (B = -0.2% per annum, 95% CI: -0.4, 0.0% per annum) baseline cartilage volume groups (P = 0.001 for interaction). Individuals with low baseline cartilage volume who were active in their occupation and/or recreational activity had greater medial cartilage volume loss than their more inactive counterparts (2.4% per annum vs 1.5% per annum, P = 0.02). Whereas people with less baseline cartilage volume are more at risk of structural knee damage with either heavy occupational or recreational workloads or both, individuals with high baseline cartilage volume may advantageously modify their risk for knee OA by participating in more frequent occupational physical activities. © The Author 2016. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  16. Baseline Report on HB2320

    ERIC Educational Resources Information Center

    State Council of Higher Education for Virginia, 2015

    2015-01-01

    Staff provides this baseline report as a summary of its preliminary considerations and initial research in fulfillment of the requirements of HB2320 from the 2015 session of the General Assembly. Codified as § 23-7.4:7, this legislation compels the Education Secretary and the State Council of Higher Education for Virginia (SCHEV) Director, in…

  17. Pediatric Heart Transplantation: Transitioning to Adult Care (TRANSIT): Baseline Findings.

    PubMed

    Grady, Kathleen L; Hof, Kathleen Van't; Andrei, Adin-Cristian; Shankel, Tamara; Chinnock, Richard; Miyamoto, Shelley; Ambardekar, Amrut V; Anderson, Allen; Addonizio, Linda; Latif, Farhana; Lefkowitz, Debra; Goldberg, Lee; Hollander, Seth A; Pham, Michael; Weissberg-Benchell, Jill; Cool, Nichole; Yancy, Clyde; Pahl, Elfriede

    2018-02-01

    Young adult solid organ transplant recipients who transfer from pediatric to adult care experience poor outcomes related to decreased adherence to the medical regimen. Our pilot trial for young adults who had heart transplant (HT) who transfer to adult care tests an intervention focused on increasing HT knowledge, self-management and self-advocacy skills, and enhancing support, as compared to usual care. We report baseline findings between groups regarding (1) patient-level outcomes and (2) components of the intervention. From 3/14 to 9/16, 88 subjects enrolled and randomized to intervention (n = 43) or usual care (n = 45) at six pediatric HT centers. Patient self-report questionnaires and medical records data were collected at baseline, and 3 and 6 months after transfer. For this report, baseline findings (at enrollment and prior to transfer to adult care) were analyzed using Chi-square and t-tests. Level of significance was p < 0.05. Baseline demographics were similar in the intervention and usual care arms: age 21.3 ± 3.2 vs 21.5 ± 3.3 years and female 44% vs 49%, respectively. At baseline, there were no differences between intervention and usual care for use of tacrolimus (70 vs 62%); tacrolimus level (mean ± SD = 6.5 ± 2.3 ng/ml vs 5.6 ± 2.3 ng/ml); average of the within patient standard deviation of the baseline mean tacrolimus levels (1.6 vs 1.3); and adherence to the medical regimen [3.6 ± 0.4 vs 3.5 ± 0.5 (1 = hardly ever to 4 = all of the time)], respectively. At baseline, both groups had a modest amount of HT knowledge, were learning self-management and self-advocacy, and perceived they were adequately supported. Baseline findings indicate that transitioning HT recipients lack essential knowledge about HT and have incomplete self-management and self-advocacy skills.

  18. Baseline factors associated with incident HIV and STI in four microbicide trials.

    PubMed

    Feldblum, Paul J; Lie, Che-Chin; Weaver, Mark A; Van Damme, Lut; Halpern, Vera; Adeiga, Adesina; Bakare, Rashidi; Schwartz, Jill; Becker, Marissa; Solomon, Suniti

    2010-10-01

    Analyzing pooled data from 4 recent microbicide trials, we aimed to determine characteristics of participants at higher risk of HIV and sexually transmitted infections (STIs), to inform targeted recruitment, preserved study power, and potentially smaller study sizes in future trials. We evaluated the relationships between participants' characteristics and the incidence of HIV, STIs, and reproductive tract infections (RTIs). We calculated incidence rates as the number of infection events divided by the person-years of observation. We applied Cox regression models to assess the relationships between baseline demographic, reproductive and behavioral factors and incident HIV, STIs and RTIs. The pooled incidence rates for HIV, chlamydia, and gonorrhea were 2.1, 6.4 and 9.9 per 100 person-years, respectively. Proportions of participants with trichomoniasis, bacterial vaginosis (BV), and candidiasis were 0.06, 0.40, and 0.40, respectively. In final multivariable models, age and education were significantly (and inversely) associated with incident HIV; baseline chlamydia, baseline trichomoniasis, and younger age were associated with incident Chlamydia; and baseline gonorrhea infection, younger age, less education, nulliparous status, baseline chlamydia, and condom use for contraception were associated with incident gonorrhea. Three factors were associated with trichomoniasis: baseline trichomoniasis infection, baseline chlamydia, and baseline BV. Only younger age was robustly associated with multiple STI outcomes in our multivariable analyses. Although there was little evidence of associations between baseline STIs and incident HIV, they were strongly associated with incident STIs. We found no evidence that measured baseline sexual behavior factors were associated with incident HIV or STIs.

  19. Clinical implementation of photon beam flatness measurements to verify beam quality.

    PubMed

    Goodall, Simon; Harding, Nicholas; Simpson, Jake; Alexander, Louise; Morgan, Steve

    2015-11-08

    This work describes the replacement of Tissue Phantom Ratio (TPR) measurements with beam profile flatness measurements to determine photon beam quality during routine quality assurance (QA) measurements. To achieve this, a relationship was derived between the existing TPR15/5 energy metric and beam flatness, to provide baseline values and clinically relevant tolerances. The beam quality was varied around two nominal beam energy values for four matched Elekta linear accelerators (linacs) by varying the bending magnet currents and reoptimizing the beam. For each adjusted beam quality the TPR15/5 was measured using an ionization chamber and Solid Water phantom. Two metrics of beam flatness were evaluated using two identical commercial ionization chamber arrays. A linear relationship was found between TPR15/5 and both metrics of flatness, for both nominal energies and on all linacs. Baseline diagonal flatness (FDN) values were measured to be 103.0% (ranging from 102.5% to 103.8%) for 6 MV and 102.7% (ranging from 102.6% to 102.8%) for 10 MV across all four linacs. Clinically acceptable tolerances of ± 2% for 6 MV, and ± 3% for 10 MV, were derived to equate to the current TPR15/5 clinical tolerance of ± 0.5%. Small variations in the baseline diagonal flatness values were observed between ionization chamber arrays; however, the rate of change of TPR15/5 with diagonal flatness was found to remain within experimental uncertainty. Measurements of beam flatness were shown to display an increased sensitivity to variations in the beam quality when compared to TPR measurements. This effect is amplified for higher nominal energy photons. The derivation of clinical baselines and associated tolerances has allowed this method to be incorporated into routine QA, streamlining the process whilst also increasing versatility. In addition, the effect of beam adjustment can be observed in real time, allowing increased practicality during corrective and preventive maintenance

  20. The relationship between baseline pupil size and intelligence.

    PubMed

    Tsukahara, Jason S; Harrison, Tyler L; Engle, Randall W

    2016-12-01

    Pupil dilations of the eye are known to correspond to central cognitive processes. However, the relationship between pupil size and individual differences in cognitive ability is not as well studied. A peculiar finding that has cropped up in this research is that those high on cognitive ability have a larger pupil size, even during a passive baseline condition. Yet these findings were incidental and lacked a clear explanation. Therefore, in the present series of studies we systematically investigated whether pupil size during a passive baseline is associated with individual differences in working memory capacity and fluid intelligence. Across three studies we consistently found that baseline pupil size is, in fact, related to cognitive ability. We showed that this relationship could not be explained by differences in mental effort, and that the effect of working memory capacity and fluid intelligence on pupil size persisted even after 23 sessions and taking into account the effect of novelty or familiarity with the environment. We also accounted for potential confounding variables such as; age, ethnicity, and drug substances. Lastly, we found that it is fluid intelligence, more so than working memory capacity, which is related to baseline pupil size. In order to provide an explanation and suggestions for future research, we also consider our findings in the context of the underlying neural mechanisms involved. Copyright © 2016 Elsevier Inc. All rights reserved.

  1. Space shuttle navigation analysis. Volume 2: Baseline system navigation

    NASA Technical Reports Server (NTRS)

    Jones, H. L.; Luders, G.; Matchett, G. A.; Rains, R. G.

    1980-01-01

    Studies related to the baseline navigation system for the orbiter are presented. The baseline navigation system studies include a covariance analysis of the Inertial Measurement Unit calibration and alignment procedures, postflight IMU error recovery for the approach and landing phases, on-orbit calibration of IMU instrument biases, and a covariance analysis of entry and prelaunch navigation system performance.

  2. The Geobiosphere Emergy Baseline: A synthesis

    EPA Science Inventory

    Following the Eighth Biennial Emergy Conference (January, 2014), the need for revisiting the procedures and assumptions used to compute the Geobiosphere Emergy Baseline (GEB) emerged as a necessity to strengthen the method of Emergy Accounting and remove sources of ambiguity and ...

  3. Enhanced GPS-based GRACE baseline determination by using a new strategy for ambiguity resolution and relative phase center variation corrections

    NASA Astrophysics Data System (ADS)

    Gu, Defeng; Ju, Bing; Liu, Junhong; Tu, Jia

    2017-09-01

    Precise relative position determination is a prerequisite for radar interferometry by formation flying satellites. It has been shown that this can be achieved by high-quality, dual-frequency GPS receivers that provide precise carrier-phase observations. The precise baseline determination between satellites flying in formation can significantly improve the accuracy of interferometric products, and has become a research interest. The key technologies of baseline determination using spaceborne dual-frequency GPS for gravity recovery and climate experiment (GRACE) formation are presented, including zero-difference (ZD) reduced dynamic orbit determination, double-difference (DD) reduced dynamic relative orbit determination, integer ambiguity resolution and relative receiver antenna phase center variation (PCV) estimation. We propose an independent baseline determination method based on a new strategy of integer ambiguity resolution and correction of relative receiver antenna PCVs, and implement the method in the NUDTTK software package. The algorithms have been tested using flight data over a period of 120 days from GRACE. With the original strategy of integer ambiguity resolution based on Melbourne-Wübbena (M-W) combinations, the average success rate is 85.6%, and the baseline precision is 1.13 mm. With the new strategy of integer ambiguity resolution based on a priori relative orbit, the average success rate and baseline precision are improved by 5.8% and 0.11 mm respectively. A relative ionosphere-free phase pattern estimation result is given in this study, and with correction of relative receiver antenna PCVs, the baseline precision is further significantly improved by 0.34 mm. For ZD reduced dynamic orbit determination, the orbit precision for each GRACE satellite A or B in three dimensions (3D) is about 2.5 cm compared to Jet Propulsion Laboratory (JPL) post science orbits. For DD reduced dynamic relative orbit determination, the final baseline precision for two

  4. Baseline series fragrance markers fail to predict contact allergy.

    PubMed

    Mann, Jack; McFadden, John P; White, Jonathan M L; White, Ian R; Banerjee, Piu

    2014-05-01

    Negative patch test results with fragrance allergy markers in the European baseline series do not always predict a negative reaction to individual fragrance substances. To determine the frequencies of positive test reactions to the 26 fragrance substances for which labelling is mandatory in the EU, and how effectively reactions to fragrance markers in the baseline series predict positive reactions to the fragrance substances that are labelled. The records of 1951 eczema patients, routinely tested with the labelled fragrance substances and with an extended European baseline series in 2011 and 2012, were retrospectively reviewed. Two hundred and eighty-one (14.4%) (71.2% females) reacted to one or more allergens from the labelled-fragrance substance series and/or a fragrance marker from the European baseline series. The allergens that were positive with the greatest frequencies were cinnamyl alcohol (48; 2.46%), Evernia furfuracea (44; 2.26%), and isoeugenol (40; 2.05%). Of the 203 patients who reacted to any of the 26 fragrances in the labelled-fragrance substance series, only 117 (57.6%) also reacted to a fragrance marker in the baseline series. One hundred and seven (52.7%) reacted to either fragrance mix I or fragrance mix II, 28 (13.8%) reacted to Myroxylon pereirae, and 13 (6.4%) reacted to hydroxyisohexyl 3-cyclohexene carboxaldehyde. These findings confirm that the standard fragrance markers fail to identify patients with contact allergies to the 26 fragrances. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  5. The quality march. National survey profiles quality improvement activities.

    PubMed

    1993-12-05

    This nationwide profile of CQI/TQM adopters and non-adopters provides important baseline information with which to chart the growing involvement of hospitals with formal quality improvement efforts. Using a stringent definition, the findings suggest rather widespread adoption of CQI/TQM, although most of it has been very recent. Further, there are systematic differences by bed size, teaching orientation, and system membership. Though the Deming method is the most popular approach to CQI/TQM, nearly as many hospitals report using a combination of approaches, and approximately 22 percent report that they have not selected any specific approach. Of particular note is the finding that those involved with CQI/TQM activities perceive fewer barriers to their quality improvement efforts than those not involved. The impact of these differences on perceived costs and outcomes will be addressed in the next issue of Hospitals & Health Networks.

  6. An automated baseline correction protocol for infrared spectra of atmospheric aerosols collected on polytetrafluoroethylene (Teflon) filters

    NASA Astrophysics Data System (ADS)

    Kuzmiakova, Adele; Dillner, Ann M.; Takahama, Satoshi

    2016-06-01

    A growing body of research on statistical applications for characterization of atmospheric aerosol Fourier transform infrared (FT-IR) samples collected on polytetrafluoroethylene (PTFE) filters (e.g., Russell et al., 2011; Ruthenburg et al., 2014) and a rising interest in analyzing FT-IR samples collected by air quality monitoring networks call for an automated PTFE baseline correction solution. The existing polynomial technique (Takahama et al., 2013) is not scalable to a project with a large number of aerosol samples because it contains many parameters and requires expert intervention. Therefore, the question of how to develop an automated method for baseline correcting hundreds to thousands of ambient aerosol spectra given the variability in both environmental mixture composition and PTFE baselines remains. This study approaches the question by detailing the statistical protocol, which allows for the precise definition of analyte and background subregions, applies nonparametric smoothing splines to reproduce sample-specific PTFE variations, and integrates performance metrics from atmospheric aerosol and blank samples alike in the smoothing parameter selection. Referencing 794 atmospheric aerosol samples from seven Interagency Monitoring of PROtected Visual Environment (IMPROVE) sites collected during 2011, we start by identifying key FT-IR signal characteristics, such as non-negative absorbance or analyte segment transformation, to capture sample-specific transitions between background and analyte. While referring to qualitative properties of PTFE background, the goal of smoothing splines interpolation is to learn the baseline structure in the background region to predict the baseline structure in the analyte region. We then validate the model by comparing smoothing splines baseline-corrected spectra with uncorrected and polynomial baseline (PB)-corrected equivalents via three statistical applications: (1) clustering analysis, (2) functional group quantification

  7. Clinical Relevance of Baseline TCP in Transcatheter Aortic Valve Replacement.

    PubMed

    Sannino, Anna; Stoler, Robert C; Hebeler, Robert F; Szerlip, Molly; Mack, Michael J; Grayburn, Paul A

    2017-10-01

    To investigate the influence of baseline thrombocytopenia (TCP) on short-term and long-term outcomes after transcatheter aortic valve replacement (TAVR). A total of 732 consecutive patients with severe, symptomatic aortic stenosis undergoing TAVR from January 2012 to December 2015 were included. Primary outcomes of interest were the relationship of baseline TCP with 30-day and 1-year all-cause mortality. Secondary outcomes of interest were procedural complications and in-hospital mortality in the same subgroups. The prevalence of TCP (defined as platelet count <150 × 109/L) at baseline was 21.9%, of whom 4.0% had moderate/severe TCP (defined as platelet count <100 × 109/L). Compared to no or mild TCP, moderate/severe TCP at baseline was associated with a significantly higher 30-day mortality (23.3% vs 2.3% and 3.1%, respectively; P<.001) and 1-year mortality (40.0% vs 8.3% and 13.4%, respectively; P<.001). In Cox regression analysis, moderate/severe baseline TCP was an independent predictor of 30-day and 1-year mortality (hazard ratio [HR], 13.18; 95% confidence interval [CI], 4.49-38.64; P<.001 and HR, 5.90; 95% CI, 2.68-13.02; P<.001, respectively). In conclusion, baseline TCP is a strong predictor of mortality in TAVR patients, possibly identifying a specific subgroup of frail patients; therefore, it should be taken into account when addressing TAVR risk.

  8. A publication database for optical long baseline interferometry

    NASA Astrophysics Data System (ADS)

    Malbet, Fabien; Mella, Guillaume; Lawson, Peter; Taillifet, Esther; Lafrasse, Sylvain

    2010-07-01

    Optical long baseline interferometry is a technique that has generated almost 850 refereed papers to date. The targets span a large variety of objects from planetary systems to extragalactic studies and all branches of stellar physics. We have created a database hosted by the JMMC and connected to the Optical Long Baseline Interferometry Newsletter (OLBIN) web site using MySQL and a collection of XML or PHP scripts in order to store and classify these publications. Each entry is defined by its ADS bibcode, includes basic ADS informations and metadata. The metadata are specified by tags sorted in categories: interferometric facilities, instrumentation, wavelength of operation, spectral resolution, type of measurement, target type, and paper category, for example. The whole OLBIN publication list has been processed and we present how the database is organized and can be accessed. We use this tool to generate statistical plots of interest for the community in optical long baseline interferometry.

  9. Change in quality of life of people with dementia recently admitted to long-term care facilities.

    PubMed

    Beerens, Hanneke C; Zwakhalen, Sandra M G; Verbeek, Hilde; Ruwaard, Dirk; Ambergen, Antonius W; Leino-Kilpi, Helena; Stephan, Astrid; Zabalegui, Adelaida; Soto, Maria; Saks, Kai; Bökberg, Christina; Sutcliffe, Caroline L; Hamers, Jan P H

    2015-06-01

    To assess which factors are associated with change in quality of life of people with dementia who have recently been admitted to long-term care facilities. Many people with dementia will be admitted to long-term care facilities at some point during their disease. It is currently unknown which factors are associated with improvement and/or deterioration of quality of life immediately following admission. An observational and longitudinal survey. Data on 343 people with dementia who have been recently admitted to long-term care facilities across eight European countries were collected between November 2010-April 2012. Quality of life was assessed by people with dementia and their proxies using the 'Quality of Life-Alzheimer's Disease scale'. Explanatory variables included cognitive status, comorbidities, activities of daily living, depressive symptoms and neuropsychiatric symptoms. Descriptive and multilevel regression analyses were performed. Better cognitive abilities at baseline were associated with a decrease in self-reported quality of life. Greater dependency and more depressive symptoms at baseline were associated with declined proxy-reported quality of life. Furthermore, an increased dependency and an increase of depressive symptoms between baseline and follow-up were associated with a decreased proxy-reported quality of life. On an individual level, three groups were identified, namely people whose quality of life: (1) decreased; (2) stayed the same; and (3) increased. Cognitive functioning, functional rehabilitation and treatment of depressive symptoms should receive special attention. However, quality of life of people with dementia does not necessarily decrease after institutionalization. © 2014 John Wiley & Sons Ltd.

  10. Back-calculating baseline creatinine overestimates prevalence of acute kidney injury with poor sensitivity.

    PubMed

    Kork, F; Balzer, F; Krannich, A; Bernardi, M H; Eltzschig, H K; Jankowski, J; Spies, C

    2017-03-01

    Acute kidney injury (AKI) is diagnosed by a 50% increase in creatinine. For patients without a baseline creatinine measurement, guidelines suggest estimating baseline creatinine by back-calculation. The aim of this study was to evaluate different glomerular filtration rate (GFR) equations and different GFR assumptions for back-calculating baseline creatinine as well as the effect on the diagnosis of AKI. The Modification of Diet in Renal Disease, the Chronic Kidney Disease Epidemiology (CKD-EPI) and the Mayo quadratic (MQ) equation were evaluated to estimate baseline creatinine, each under the assumption of either a fixed GFR of 75 mL min -1  1.73 m -2 or an age-adjusted GFR. Estimated baseline creatinine, diagnoses and severity stages of AKI based on estimated baseline creatinine were compared to measured baseline creatinine and corresponding diagnoses and severity stages of AKI. The data of 34 690 surgical patients were analysed. Estimating baseline creatinine overestimated baseline creatinine. Diagnosing AKI based on estimated baseline creatinine had only substantial agreement with AKI diagnoses based on measured baseline creatinine [Cohen's κ ranging from 0.66 (95% CI 0.65-0.68) to 0.77 (95% CI 0.76-0.79)] and overestimated AKI prevalence with fair sensitivity [ranging from 74.3% (95% CI 72.3-76.2) to 90.1% (95% CI 88.6-92.1)]. Staging AKI severity based on estimated baseline creatinine had moderate agreement with AKI severity based on measured baseline creatinine [Cohen's κ ranging from 0.43 (95% CI 0.42-0.44) to 0.53 (95% CI 0.51-0.55)]. Diagnosing AKI and staging AKI severity on the basis of estimated baseline creatinine in surgical patients is not feasible. Patients at risk for post-operative AKI should have a pre-operative creatinine measurement to adequately assess post-operative AKI. © 2016 Scandinavian Physiological Society. Published by John Wiley & Sons Ltd.

  11. Solid Waste Program technical baseline description

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Carlson, A.B.

    1994-07-01

    The system engineering approach has been taken to describe the technical baseline under which the Solid Waste Program is currently operating. The document contains a mission analysis, function analysis, system definition, documentation requirements, facility and project bases, and uncertainties facing the program.

  12. Solar central electric power generation - A baseline design

    NASA Technical Reports Server (NTRS)

    Powell, J. C.

    1976-01-01

    The paper presents the conceptual technical baseline design of a solar electric power plant using the central receiver concept, and derives credible cost estimates from the baseline design. The major components of the plant - heliostats, tower, receiver, tower piping, and thermal storage - are discussed in terms of technical and cost information. The assumed peak plant output is 215 MW(e), over 4000 daylight hours. The contribution of total capital investment to energy cost is estimated to be about 55 mills per kwh in mid-1974 dollars.

  13. Shuttle mission simulator baseline definition report, volume 1

    NASA Technical Reports Server (NTRS)

    Burke, J. F.; Small, D. E.

    1973-01-01

    A baseline definition of the space shuttle mission simulator is presented. The subjects discussed are: (1) physical arrangement of the complete simulator system in the appropriate facility, with a definition of the required facility modifications, (2) functional descriptions of all hardware units, including the operational features, data demands, and facility interfaces, (3) hardware features necessary to integrate the items into a baseline simulator system to include the rationale for selecting the chosen implementation, and (4) operating, maintenance, and configuration updating characteristics of the simulator hardware.

  14. The importance of proper administration and interpretation of neuropsychological baseline and postconcussion computerized testing.

    PubMed

    Moser, Rosemarie Scolaro; Schatz, Philip; Lichtenstein, Jonathan D

    2015-01-01

    Media coverage, litigation, and new legislation have resulted in a heightened awareness of the prevalence of sports concussion in both adult and youth athletes. Baseline and postconcussion testing is now commonly used for the assessment and management of sports-related concussion in schools and in youth sports leagues. With increased use of computerized neurocognitive sports concussion testing, there is a need for standards for proper administration and interpretation. To date, there has been a lack of standardized procedures by which assessments are administered. More specifically, individuals who are not properly trained often interpret test results, and their methods of interpretation vary considerably. The purpose of this article is to outline factors affecting the validity of test results, to provide examples of misuse and misinterpretation of test results, and to communicate the need to administer testing in the most effective and useful manner. An increase in the quality of test administration and application may serve to decrease the prevalence of invalid test results and increase the accuracy and utility of baseline test results if an athlete sustains a concussion. Standards for test use should model the American Psychological Association and Centers for Disease Control and Prevention guidelines, as well as the recent findings of the joint position paper on computerized neuropsychological assessment devices.

  15. Analysis of surface EMG baseline for detection of hidden muscle activity

    NASA Astrophysics Data System (ADS)

    Zhang, Xu; Zhou, Ping

    2014-02-01

    Objective. This study explored the feasibility of detecting hidden muscle activity in surface electromyogram (EMG) baseline. Approach. Power spectral density (PSD) analysis and multi-scale entropy (MSE) analysis were used. Both analyses were applied to computer simulations of surface EMG baseline with the presence (representing activity data) or absence (representing reference data) of hidden muscle activity, as well as surface electrode array EMG baseline recordings of healthy control and amyotrophic lateral sclerosis (ALS) subjects. Main results. Although the simulated reference data and the activity data yielded no distinguishable difference in the time domain, they demonstrated a significant difference in the frequency and signal complexity domains with the PSD and MSE analyses. For a comparison using pooled data, such a difference was also observed when the PSD and MSE analyses were applied to surface electrode array EMG baseline recordings of healthy control and ALS subjects, which demonstrated no distinguishable difference in the time domain. Compared with the PSD analysis, the MSE analysis appeared to be more sensitive for detecting the difference in surface EMG baselines between the two groups. Significance. The findings implied the presence of a hidden muscle activity in surface EMG baseline recordings from the ALS subjects. To promote the presented analysis as a useful diagnostic or investigatory tool, future studies are necessary to assess the pathophysiological nature or origins of the hidden muscle activity, as well as the baseline difference at the individual subject level.

  16. Analysis of Surface EMG Baseline for Detection of Hidden Muscle Activity

    PubMed Central

    Zhang, Xu; Zhou, Ping

    2014-01-01

    Objective This study explored the feasibility of detecting hidden muscle activity in surface electromyogram (EMG) baseline. Approach Power spectral density (PSD) analysis and multi-scale entropy (MSE) analysis were used respectively. Both analyses were applied to computer simulations of surface EMG baseline with presence (representing activity data) or absence (representing reference data) of hidden muscle activity, as well as surface electrode array EMG baseline recordings of healthy control and amyotrophic lateral sclerosis (ALS) subjects. Main results Although the simulated reference data and the activity data yielded no distinguishable difference in the time domain, they demonstrated a significant difference in the frequency and signal complexity domains with the PSD and MSE analyses. For a comparison using pooled data, such a difference was also observed when the PSD and MSE analyses were applied to surface electrode array EMG baseline recordings of healthy control and ALS subjects, which demonstrated no distinguishable difference in the time domain. Compared with the PSD analysis, the MSE analysis appeared to be more sensitive for detecting the difference in surface EMG baselines between the two groups. Significance The findings implied presence of hidden muscle activity in surface EMG baseline recordings from the ALS subjects. To promote the presented analysis as a useful diagnostic or investigatory tool, future studies are necessary to assess the pathophysiological nature or origins of the hidden muscle activity, as well as the baseline difference at the individual subject level. PMID:24445526

  17. Marine biodiversity baseline for Área de Conservación Guanacaste, Costa Rica: published records.

    PubMed

    Cortés, Jorge

    2017-01-01

    The diversity of tropical marine organisms has not been studied as intensively as the terrestrial biota worldwide. Additionally, marine biodiversity research in the tropics lags behind other regions. The 43,000 ha Sector Marino of Área de Conservación Guanacaste (ACG, Marine Sector of Guanacaste Conservation Area), on the North Pacific coast of Costa Rica is no exception. For more than four decades, the terrestrial flora and fauna has been studied continuously. The ACG marine biodiversity was studied in the 1930's by expeditions that passed through the area, but not much until the 1990's, except for the marine turtles. In the mid 1990's the Center for Research in Marine Science and Limnology (CIMAR) of the Universidad de Costa Rica (UCR) initiated the exploration of the marine environments and organisms of ACG. In 2015, ACG, in collaboration with CIMAR, started the BioMar project whose goal is to inventory the species of the marine sector of ACG (BioMar ACG project). As a baseline, here I have compiled the published records of marine ACG species, and found that 594 marine species have been reported, representing 15.5% of the known species of the Pacific coast of Costa Rica. The most diverse groups were the crustaceans, mollusks and cnidarians comprising 71.7% of the ACG species. Some taxa, such as mangroves and fish parasites are well represented in ACG when compared to the rest of the Costa Rican coast but others appear to be greatly underrepresented, for example, red algae, polychaetes, copepods, equinoderms, and marine fishes and birds, which could be due to sampling bias. Thirty species have been originally described with specimens from ACG, and 89 species are not known from other localities on the Pacific coast of Costa Rica except ACG. Most of the sampling has been concentrated in a few localities in Sector Marino, Playa Blanca and Islas Murciélago, and in the nearby waters of Bahía Santa Elena. In an effort to fill this gap, CIMAR is collaborating with

  18. Marine biodiversity baseline for Área de Conservación Guanacaste, Costa Rica: published records

    PubMed Central

    Cortés, Jorge

    2017-01-01

    Abstract The diversity of tropical marine organisms has not been studied as intensively as the terrestrial biota worldwide. Additionally, marine biodiversity research in the tropics lags behind other regions. The 43,000 ha Sector Marino of Área de Conservación Guanacaste (ACG, Marine Sector of Guanacaste Conservation Area), on the North Pacific coast of Costa Rica is no exception. For more than four decades, the terrestrial flora and fauna has been studied continuously. The ACG marine biodiversity was studied in the 1930’s by expeditions that passed through the area, but not much until the 1990’s, except for the marine turtles. In the mid 1990’s the Center for Research in Marine Science and Limnology (CIMAR) of the Universidad de Costa Rica (UCR) initiated the exploration of the marine environments and organisms of ACG. In 2015, ACG, in collaboration with CIMAR, started the BioMar project whose goal is to inventory the species of the marine sector of ACG (BioMar ACG project). As a baseline, here I have compiled the published records of marine ACG species, and found that 594 marine species have been reported, representing 15.5% of the known species of the Pacific coast of Costa Rica. The most diverse groups were the crustaceans, mollusks and cnidarians comprising 71.7% of the ACG species. Some taxa, such as mangroves and fish parasites are well represented in ACG when compared to the rest of the Costa Rican coast but others appear to be greatly underrepresented, for example, red algae, polychaetes, copepods, equinoderms, and marine fishes and birds, which could be due to sampling bias. Thirty species have been originally described with specimens from ACG, and 89 species are not known from other localities on the Pacific coast of Costa Rica except ACG. Most of the sampling has been concentrated in a few localities in Sector Marino, Playa Blanca and Islas Murciélago, and in the nearby waters of Bahía Santa Elena. In an effort to fill this gap, CIMAR is

  19. Structured data quality reports to improve EHR data quality.

    PubMed

    Taggart, Jane; Liaw, Siaw-Teng; Yu, Hairong

    2015-12-01

    To examine whether a structured data quality report (SDQR) and feedback sessions with practice principals and managers improve the quality of routinely collected data in EHRs. The intervention was conducted in four general practices participating in the Fairfield neighborhood electronic Practice Based Research Network (ePBRN). Data were extracted from their clinical information systems and summarised as a SDQR to guide feedback to practice principals and managers at 0, 4, 8 and 12 months. Data quality (DQ) metrics included completeness, correctness, consistency and duplication of patient records. Information on data recording practices, data quality improvement, and utility of SDQRs was collected at the feedback sessions at the practices. The main outcome measure was change in the recording of clinical information and level of meeting Royal Australian College of General Practice (RACGP) targets. Birth date was 100% and gender 99% complete at baseline and maintained. DQ of all variables measured improved significantly (p<0.01) over 12 months, but was not sufficient to comply with RACGP standards. Improvement was greatest with allergies. There was no significant change in duplicate records. SDQRs and feedback sessions support general practitioners and practice managers to focus on improving the recording of patient information. However, improved practice DQ, was not sufficient to meet RACGP targets. Randomised controlled studies are required to evaluate strategies to improve data quality and any associated improved safety and quality of care. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  20. Adapting the M3 Surveillance Metrics for an Unknown Baseline

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hamada, Michael Scott; Abes, Jeff I.; Jaramillo, Brandon Michael Lee

    The original M 3 surveillance metrics assume that the baseline is known. In this article, adapted M 3 metrics are presented when the baseline is not known and estimated by available data. Deciding on how much available data is enough is also discussed.

  1. IEA Wind Task 26: Offshore Wind Farm Baseline Documentation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Smart, Gavin; Smith, Aaron; Warner, Ethan

    This document has been produced to provide the definition and rationale for the Baseline Offshore Wind Farm established within IEA Wind Task 26--Cost of Wind Energy. The Baseline has been developed to provide a common starting point for country comparisons and sensitivity analysis on key offshore wind cost and value drivers. The baseline project reflects an approximate average of the characteristics of projects installed between 2012 and 2014, with the project life assumed to be 20 years. The baseline wind farm is located 40 kilometres (km) from construction and operations and maintenance (O&M) ports and from export cable landfall. Themore » wind farm consists of 100 4-megawatt (MW) wind turbines mounted on monopile foundations in an average water depth of 25 metres (m), connected by 33-kilovolt (kV) inter-array cables. The arrays are connected to a single offshore substation (33kV/220kV) mounted on a jacket foundation, with the substation connected via a single 220kV export cable to an onshore substation, 10km from landfall. The wind farm employs a port-based O&M strategy using crew-transfer vessels.« less

  2. Consideration of the baseline environment in examples of voluntary SEAs from Scotland

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wright, Fiona

    2007-07-15

    Evidence from analysing and evaluating examples of three voluntary SEAs prepared in Scotland in the mid-late 1990s showed that different spatial and temporal scales were used when providing a baseline environment description. The SEAs analysed were prepared for: a wind farm siting programme that looked at national and short-term impacts; a land use plan that looked at regional and short-term impacts; and a transport plan that examined local and medium-term impacts. It was found that the two SEAs prepared by local government only considered impacts on the baseline environment within their jurisdictional boundaries whilst the SEA prepared by the privatemore » business considered impacts on the national baseline. A mixture of baseline data about planning, economic, environmental and social issues were included in the SEAs, however, evidence suggested that each SEA only focussed on those baseline features that might be significantly affected by the proposal. Each SEA also made extensive use of existing baseline information available from a variety of sources including local, and central government records and information from statutory bodies. All of the SEAs acknowledged that baseline data deficiencies existed and in certain cases steps were taken to obtain primary field data to help address these, however, it was also acknowledged that resource restrictions and decision-making deadlines limited the amount of primary baseline data that could be collected.« less

  3. Baselining PMU Data to Find Patterns and Anomalies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Amidan, Brett G.; Follum, James D.; Freeman, Kimberly A.

    This paper looks at the application of situational awareness methodologies with respect to power grid data. These methodologies establish baselines that look for typical patterns and atypical behavior in the data. The objectives of the baselining analyses are to provide: real-time analytics, the capability to look at historical trends and events, and reliable predictions of the near future state of the grid. Multivariate algorithms were created to establish normal baseline behavior and then score each moment in time according to its variance from the baseline. Detailed multivariate analytical techniques are described in this paper that produced ways to identify typicalmore » patterns and atypical behavior. In this case, atypical behavior is behavior that is unenvisioned. Visualizations were also produced to help explain the behavior that was identified mathematically. Examples are shown to help describe how to read and interpret the analyses and visualizations. Preliminary work has been performed on PMU data sets from BPA (Bonneville Power Administration) and EI (Eastern Interconnect). Actual results are not fully shown here because of confidentiality issues. Comparisons between atypical events found mathematically and actual events showed that many of the actual events are also atypical events; however there are many atypical events that do not correlate to any actual events. Additional work needs to be done to help classify the atypical events into actual events, so that the importance of the events can be better understood.« less

  4. Budget Impact of a Comprehensive Nutrition-Focused Quality Improvement Program for Malnourished Hospitalized Patients

    PubMed Central

    Sulo, Suela; Feldstein, Josh; Partridge, Jamie; Schwander, Bjoern; Sriram, Krishnan; Summerfelt, Wm. Thomas

    2017-01-01

    Background Nutrition interventions can alleviate the burden of malnutrition by improving patient outcomes; however, evidence on the economic impact of medical nutrition intervention remains limited. A previously published nutrition-focused quality improvement program targeting malnourished hospitalized patients showed that screening patients with a validated screening tool at admission, rapidly administering oral nutritional supplements, and educating patients on supplement adherence result in significant reductions in 30-day unplanned readmissions and hospital length of stay. Objectives To assess the potential cost-savings associated with decreased 30-day readmissions and hospital length of stay in malnourished inpatients through a nutrition-focused quality improvement program using a web-based budget impact model, and to demonstrate the clinical and fiscal value of the intervention. Methods The reduction in readmission rate and length of stay for 1269 patients enrolled in the quality improvement program (between October 13, 2014, and April 2, 2015) were compared with the pre–quality improvement program baseline and validation cohorts (4611 patients vs 1319 patients, respectively) to calculate potential cost-savings as well as to inform the design of the budget impact model. Readmission rate and length-of-stay reductions were calculated by determining the change from baseline to post–quality improvement program as well as the difference between the validation cohort and the post–quality improvement program, respectively. Results As a result of improved health outcomes for the treated patients, the nutrition-focused quality improvement program led to a reduction in 30-day hospital readmissions and length of stay. The avoided hospital readmissions and reduced number of days in the hospital for the patients in the quality improvement program resulted in cost-savings of $1,902,933 versus the pre–quality improvement program baseline cohort, and $4

  5. Budget Impact of a Comprehensive Nutrition-Focused Quality Improvement Program for Malnourished Hospitalized Patients.

    PubMed

    Sulo, Suela; Feldstein, Josh; Partridge, Jamie; Schwander, Bjoern; Sriram, Krishnan; Summerfelt, Wm Thomas

    2017-07-01

    Nutrition interventions can alleviate the burden of malnutrition by improving patient outcomes; however, evidence on the economic impact of medical nutrition intervention remains limited. A previously published nutrition-focused quality improvement program targeting malnourished hospitalized patients showed that screening patients with a validated screening tool at admission, rapidly administering oral nutritional supplements, and educating patients on supplement adherence result in significant reductions in 30-day unplanned readmissions and hospital length of stay. To assess the potential cost-savings associated with decreased 30-day readmissions and hospital length of stay in malnourished inpatients through a nutrition-focused quality improvement program using a web-based budget impact model, and to demonstrate the clinical and fiscal value of the intervention. The reduction in readmission rate and length of stay for 1269 patients enrolled in the quality improvement program (between October 13, 2014, and April 2, 2015) were compared with the pre-quality improvement program baseline and validation cohorts (4611 patients vs 1319 patients, respectively) to calculate potential cost-savings as well as to inform the design of the budget impact model. Readmission rate and length-of-stay reductions were calculated by determining the change from baseline to post-quality improvement program as well as the difference between the validation cohort and the post-quality improvement program, respectively. As a result of improved health outcomes for the treated patients, the nutrition-focused quality improvement program led to a reduction in 30-day hospital readmissions and length of stay. The avoided hospital readmissions and reduced number of days in the hospital for the patients in the quality improvement program resulted in cost-savings of $1,902,933 versus the pre-quality improvement program baseline cohort, and $4,896,758 versus the pre-quality improvement program in the

  6. Future long-baseline neutrino oscillations: View from Asia

    NASA Astrophysics Data System (ADS)

    Hayato, Yoshinari

    2015-07-01

    Accelerator based long-baseline neutrino oscillation experiments have been playing important roles in revealing the nature of neutrinos. However, it turned out that the current experiments are not sufficient to study two major remaining problems, the CP violation in the lepton sector and the mass hierarchy of neutrinos. Therefore, several new experiments have been proposed. Among of them, two accelerator based long-baseline neutrino oscillation experiments, the J-PARC neutrino beam and Hyper-Kamiokande, and MOMENT, have been proposed in Asia. These two projects are reviewed in this article.

  7. Baseline estimation in flame's spectra by using neural networks and robust statistics

    NASA Astrophysics Data System (ADS)

    Garces, Hugo; Arias, Luis; Rojas, Alejandro

    2014-09-01

    This work presents a baseline estimation method in flame spectra based on artificial intelligence structure as a neural network, combining robust statistics with multivariate analysis to automatically discriminate measured wavelengths belonging to continuous feature for model adaptation, surpassing restriction of measuring target baseline for training. The main contributions of this paper are: to analyze a flame spectra database computing Jolliffe statistics from Principal Components Analysis detecting wavelengths not correlated with most of the measured data corresponding to baseline; to systematically determine the optimal number of neurons in hidden layers based on Akaike's Final Prediction Error; to estimate baseline in full wavelength range sampling measured spectra; and to train an artificial intelligence structure as a Neural Network which allows to generalize the relation between measured and baseline spectra. The main application of our research is to compute total radiation with baseline information, allowing to diagnose combustion process state for optimization in early stages.

  8. A proposal to create an extension to the European baseline series.

    PubMed

    Wilkinson, Mark; Gallo, Rosella; Goossens, An; Johansen, Jeanne D; Rustemeyer, Thomas; Sánchez-Pérez, Javier; Schuttelaar, Marie L; Uter, Wolfgang

    2018-02-01

    The current European baseline series consists of 30 allergens, and was last updated in 2015. To use data from the European Surveillance System on Contact Allergies (ESSCA) to propose an extension to the European baseline series in response to changes in environmental exposures. Data from departmental and national extensions to the baseline series, together with some temporary additions from departments contributing to the ESSCA, were collated during 2013-2014. In total, 31689 patients were patch tested in 46 European departments. Many departments and national groups already consider the current European baseline series to be a suboptimal screen, and use their own extensions to it. The haptens tested are heterogeneous, although there are some consistent themes. Potential haptens to include in an extension to the European baseline series comprise sodium metabisulfite, formaldehyde-releasing preservatives, additional markers of fragrance allergy, propolis, Compositae mix, and 2-hydroxyethyl methacrylate. In combination with other published work from the ESSCA, changes to the current European baseline series are proposed for discussion. As well as addition of the allergens listed above, it is suggested that primin and clioquinol should be deleted from the series, owing to reduced environmental exposure. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  9. Predictors and Outcomes of Health–Related Quality of Life in Adults with CKD

    PubMed Central

    Lash, James P.; Xie, Dawei; Pan, Qiang; DeLuca, Jennifer; Kanthety, Radhika; Kusek, John W.; Lora, Claudia M.; Nessel, Lisa; Ricardo, Ana C.; Wright Nunes, Julie; Fischer, Michael J.

    2016-01-01

    Background and objectives Low health–related quality of life is associated with increased mortality in patients with ESRD. However, little is known about demographic and clinical factors associated with health–related quality of life or its effect on outcomes in adults with CKD. Design, settings, participants, & measurements Data from 3837 adult participants with mild to severe CKD enrolled in the prospective observational Chronic Renal Insufficiency Cohort and Hispanic Chronic Renal Insufficiency Cohort Studies were analyzed. Health–related quality of life was assessed at baseline with the Kidney Disease Quality of Life-36 and its five subscales: mental component summary, physical component summary, burden of kidney disease (burden), effects of kidney disease (effects), and symptoms and problems of kidney disease (symptoms). Low health–related quality of life was defined as baseline score >1 SD below the mean. Using Cox proportional hazards analysis, the relationships between low health–related quality of life and the following outcomes were examined: (1) CKD progression (50% eGFR loss or incident ESRD), (2) incident cardiovascular events, and (3) all-cause death. Results Younger age, women, low education, diabetes, vascular disease, congestive heart failure, obesity, and lower eGFR were associated with low baseline health–related quality of life (P<0.05). During a median follow-up of 6.2 years, there were 1055 CKD progression events, 841 cardiovascular events, and 694 deaths. Significantly higher crude rates of CKD progression, incident cardiovascular events, and all-cause death were observed among participants with low health–related quality of life in all subscales (P<0.05). In fully adjusted models, low physical component summary, effects, and symptoms subscales were independently associated with a higher risk of incident cardiovascular events and death, whereas low mental component summary was independently associated with a higher risk of death

  10. Loss of quality of life associated with genital warts: baseline analyses from a prospective study.

    PubMed

    Sénécal, Martin; Brisson, Marc; Maunsell, Elizabeth; Ferenczy, Alex; Franco, Eduardo L; Ratnam, Sam; Coutlée, François; Palefsky, Joel M; Mansi, James A

    2011-04-01

    The quadrivalent human papillomavirus (HPV) vaccine is effective against HPV types responsible for 90% of anogenital warts. This study estimated the quality of life lost to genital warts using the EQ-5D, a generic instrument widely used for applications in economic analyses. The findings are described in terms that are more specific to individuals with genital warts using psychosocial questions adapted from the HPV impact profile, a measure developed for HPV-related conditions. Between September 2006 and February 2008, 42 physicians across Canada recruited 330 consenting patients 18 years and older with genital warts, either at the first or follow-up visit for an initial or recurrent episode. The quality of life lost associated with genital warts was estimated by the difference between participants' EQ-5D scores and age and gender-specific population norms. The study questionnaire was self-completed by 270 participants who were aged 31.5 years (SD 10.4) on average. The majority of participants were women (53.3%), heterosexual (93.5%) and in a stable relationship (66.0%). Genital warts were associated with detriments in the EQ-5D domains of anxiety/depression, pain/discomfort and usual activities. The absolute difference in the EQ-5D utility score and the EQ-VAS health status between genital warts patients and population norms was 9.9 (95% CI 7.3 to 12.5) and 6.0 (95% CI 4.1 to 7.9) percentage points, respectively. These results did not vary significantly according to patient age, gender, time since first episode or number of episodes. The results suggest that genital warts negatively affect the wellbeing of men and women as reflected by poorer quality of life scores compared with population norms.

  11. Dietary and physical activity behaviours related to obesity-specific quality of life and work productivity: baseline results from a worksite trial.

    PubMed

    Cash, Stephanie Whisnant; Beresford, Shirley A A; Henderson, Jo Ann; McTiernan, Anne; Xiao, Liren; Wang, C Y; Patrick, Donald L

    2012-09-28

    Obesity is associated with impaired health-related quality of life (QOL) and reduced productivity; less is known about the effect of dietary factors. The present study investigated how dietary behaviours, physical activity and BMI relate to weight-specific QOL and work productivity. The study was conducted in thirty-one small blue-collar and service industry worksites in Seattle. Participants were 747 employees (33·5 % non-White). Measures included self-reported servings of fruits and vegetables, dietary behaviours such as fast food consumption, Godin free-time physical activity scores, measured height and weight, Obesity and Weight-Loss QOL (OWLQOL) scores, and Work Limitations Questionnaire scores. Baseline data were analysed using linear mixed models separately for men (n 348) and women (n 399), since sex modified the effects. BMI was negatively associated with OWLQOL in both women (P < 0·001) and men (P < 0·001). The linear effect estimate for OWLQOL scores associated with a one-category increase in BMI was 30 (95 % CI 25, 44) % for women and 14 (95 % CI 10, 17) % for men. BMI was positively associated with productivity loss only in women (exp(slope) = 1·46, 95 % CI 1·02, 2·11, P = 0·04). Eating while doing another activity was negatively associated with OWLQOL scores in men (P = 0·0006, independent of BMI) and with productivity in women (P = 0·04, although the effect diminished when adjusting for BMI). Fast-food meals were associated with decreased productivity in men (P = 0·038, independent of BMI). The results suggest that obesogenic dietary behaviours and higher BMI are associated with decreased QOL and productivity to different degrees in women and men.

  12. 40 CFR 1042.825 - Baseline determination.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... a used engine to be the emission-data engine for the engine family for testing. Using good engineering judgment, select the engine configuration expected to represent the most common configuration in... adjust it differently, consistent with good engineering judgment. (d) Test the baseline engine four times...

  13. 40 CFR 1042.825 - Baseline determination.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... a used engine to be the emission-data engine for the engine family for testing. Using good engineering judgment, select the engine configuration expected to represent the most common configuration in... adjust it differently, consistent with good engineering judgment. (d) Test the baseline engine four times...

  14. 76 FR 28017 - NorthWestern Corporation; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-13

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR11-102-002] NorthWestern Corporation; Notice of Baseline Filing Take notice that on May 5, 2011, NorthWestern Corporation submitted a revised baseline filing of their Statement of Operating Conditions for services provided under Section 311...

  15. NREL Updates Baseline Cost and Performance Data for Electricity Generation

    Science.gov Websites

    Technologies | News | NREL Updates Baseline Cost and Performance Data for Electricity Generation Technologies News Release: NREL Updates Baseline Cost and Performance Data for Electricity generation technology cost and performance data used to support and inform electric sector analysis in the

  16. 75 FR 30014 - Consumers Energy Company; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-28

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR10-25-000] Consumers Energy Company; Notice of Baseline Filing May 21, 2010. Take notice that on May 17, 2010, Consumers Energy Company (Consumers) submitted a baseline filing of its Statement of Operating Conditions for the...

  17. 75 FR 31429 - Atmos Pipeline-Texas; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-03

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR10-27-000] Atmos Pipeline--Texas; Notice of Baseline Filing May 27, 2010. Take notice that on May 27, 2010, Atmos Pipeline--Texas submitted a baseline filing of its Statement of Operating Conditions for interruptible transportation...

  18. 40 CFR 80.1280 - How are refinery benzene baselines calculated?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 17 2014-07-01 2014-07-01 false How are refinery benzene baselines... PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Benzene Averaging, Banking and Trading (abt) Program § 80.1280 How are refinery benzene baselines calculated? (a) A refinery's benzene...

  19. 40 CFR 80.1280 - How are refinery benzene baselines calculated?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 17 2012-07-01 2012-07-01 false How are refinery benzene baselines... PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Benzene Averaging, Banking and Trading (abt) Program § 80.1280 How are refinery benzene baselines calculated? (a) A refinery's benzene...

  20. 40 CFR 80.1280 - How are refinery benzene baselines calculated?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false How are refinery benzene baselines... PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Benzene Averaging, Banking and Trading (abt) Program § 80.1280 How are refinery benzene baselines calculated? (a) A refinery's benzene...

  1. 40 CFR 80.1280 - How are refinery benzene baselines calculated?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 16 2011-07-01 2011-07-01 false How are refinery benzene baselines... PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Benzene Averaging, Banking and Trading (abt) Program § 80.1280 How are refinery benzene baselines calculated? (a) A refinery's benzene...

  2. 40 CFR 80.1280 - How are refinery benzene baselines calculated?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 17 2013-07-01 2013-07-01 false How are refinery benzene baselines... PROGRAMS (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Gasoline Benzene Averaging, Banking and Trading (abt) Program § 80.1280 How are refinery benzene baselines calculated? (a) A refinery's benzene...

  3. 76 FR 51963 - Cobra Pipeline Ltd.; Notice of Baseline Filings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-19

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR11-122-000] Cobra Pipeline Ltd.; Notice of Baseline Filings Take notice that on August 12, 2011, Cobra Pipeline Ltd. submitted a revised baseline filing of their Statement of Operating Conditions for services provided under Section 311...

  4. Detection of atmospheric pressure loading using very long baseline interferometry measurements

    NASA Technical Reports Server (NTRS)

    Vandam, T. M.; Herring, T. A.

    1994-01-01

    Loading of the Earth by the temporal redistribution of global atmospheric mass is likely to displace the positions of geodetic monuments by tens of millimeters both vertically and horizontally. Estimates of these displacements are determined by convolving National Meteorological Center (NMC) global values of atmospheric surface pressure with Farrell's elastic Green's functions. An analysis of the distances between radio telescopes determined by very long baseline interferometry (VLBI) between 1984 and 1992 reveals that in many of the cases studied there is a significant contribution to baseline length change due to atmospheric pressure loading. Our analysis covers intersite distances of between 1000 and 10,000 km and is restricted to those baselines measured more than 100 times. Accounting for the load effects (after first removing a best fit slope) reduces the weighted root-mean-square (WRMS) scatter of the baseline length residuals on 11 of the 22 baselines investigated. The slight degradation observed in the WRMS scatter on the remaining baselines is largely consistent with the expected statistical fluctuations when a small correction is applied to a data set having a much larger random noise. The results from all baselines are consistent with approximately 60% of the computed pressure contribution being present in the VLBI length determinations. Site dependent coefficients determined by fitting local pressure to the theoretical radial displacement are found to reproduce the deformation caused by the regional pressure to within 25% for most inland sites. The coefficients are less reliable at near coastal and island stations.

  5. Effects of baseline risk information on social and individual choices.

    PubMed

    Gyrd-Hansen, Dorte; Kristiansen, Ivar Sønbø; Nexøe, Jørgen; Nielsen, Jesper Bo

    2002-01-01

    This article analyzes preferences for risk reductions in the context of individual and societal decision making. The effect of information on baseline risk is analyzed in both contexts. The results indicate that if individuals are to imagine that they suffer from 1 low-risk and 1 high-risk ailment, and are offered a specified identical absolute risk reduction, a majority will ceteris paribus opt for treatment of the low-risk ailment. A different preference structure is elicited when priority questions are framed as social choices. Here, a majority will prefer to treat the high-risk group of patients. The preference reversal demonstrates the extent to which baseline risk information can influence preferences in different choice settings. It is argued that presentation of baseline risk information may induce framing effects that lead to nonoptimal resource allocations. A solution to this problem may be to not present group-specific baseline risk information when eliciting preferences.

  6. Interpreting Bodies. Elena Castellani (ed.) Interpreting Bodies: Classical and Quantum Objects in Modern Physics (Princeton: Princeton University Press, 1998), viii+329 pp., ISBN 0-691-01725-5, paperback, 19.95 US, ISBN 0-691-01724-7, cloth, 65.00 US.

    NASA Astrophysics Data System (ADS)

    Ruetsche, Laura

    The objects of the empirical science known as particle physics are not like objects ordinarily conceived. Physicists' particles can enter states strangely entangled with those of other particles; they can obey statistics which suggest that they lack genidentity; their properties (some think) are created in measurement, or (others think) can only be limned from the symmetries of the theory describing them. 'The implications of contemporary physical theories for the debate on the nature of objects' provides 'the central theme' (p. 4) of Interpreting Bodies, editor Elena Castellani's new collection of essays. Contributions to the volume vary dramatically in vintage (Born's and Reichenbach's are well into middle age; others appear here for the first time); in approach (the collection includes Giuliano Toraldo diFrancia's nine-page history of the object concept from Democritus to d'Espagnat, Peter Mittelstaedt's discussion of the Kantian constitution of quantum objects, and Giulo Peruzzi's explication of the scattering cross section and its role in experimental particle physics); and in intended audience. Lacking the space to treat each contribution in turn, I will focus on those dealing with the problem of the One and the Many.

  7. 75 FR 38801 - PELICO Pipeline, LLC; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-06

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR10-41-000] PELICO Pipeline, LLC; Notice of Baseline Filing June 28, 2010. Take notice that on June 22, 2010, PELICO Pipeline, LLC submitted a baseline filing of its Statement of Operating Conditions for services provided under section 311...

  8. Neuropsychiatric symptoms in systemic lupus erythematosus: impact on quality of life.

    PubMed

    Monahan, R C; Beaart-van de Voorde, L J J; Steup-Beekman, G M; Magro-Checa, C; Huizinga, T W J; Hoekman, J; Kaptein, A A

    2017-10-01

    Objective Assess quality of life in patients with systemic lupus erythematosus (SLE) presenting with neuropsychiatric symptoms (neuropsychiatric SLE, NPSLE). Methods Quality of life was assessed using the Short-Form 36 item Health Survey (SF-36) in patients visiting the Leiden NPSLE clinic at baseline and at follow-up. SF-36 subscales and summary scores were calculated and compared with quality of life of the general Dutch population and patients with other chronic diseases. Results At baseline, quality of life was assessed in 248 SLE patients, of whom 98 had NPSLE (39.7%). Follow-up data were available for 104 patients (42%), of whom 64 had NPSLE (61.5%). SLE patients presenting neuropsychiatric symptoms showed a significantly reduced quality of life in all subscales of the SF-36. Quality of life at follow-up showed a significant improvement in physical functioning role ( p = 0.001), social functioning ( p = 0.007), vitality ( p = 0.023), mental health ( p = 0.014) and mental component score ( p = 0.042) in patients with neuropsychiatric symptoms not attributed to SLE, but no significant improvement was seen in patients with NPSLE. Conclusion Quality of life is significantly reduced in patients with SLE presenting neuropsychiatric symptoms compared with the general population and patients with other chronic diseases. Quality of life remains considerably impaired at follow-up. Our results illustrate the need for biopsychosocial care in patients with SLE and neuropsychiatric symptoms.

  9. A baseline study of coastal water quality in the Lembeh Strait of North Sulawesi, Indonesia, in 2013.

    PubMed

    Baohong, Chen; Muchtar, Muswerry; Tingting, Fu; Hongzhe, Chen; Jigang, Wang; Kaiwen, Zhou; Jianguo, Du; Hui, Lin; Bin, Chen

    2016-03-15

    The concentrations of nutrients (NO2-N, NO3-N, NH4-N, PO4-P, and SiO3-Si) and their ratios in the Lembeh Strait were estimated in April 2013, off the northeastern coast of Sulawesi in Indonesia. The concentrations of dissolved inorganic nitrogen (DIN) (NO2-N+NO3-N+NH4-N) and PO4-P were low, with a maximum of 0.181 and 0.007 mg/L, respectively. P was found to be the limiting factor controlling phytoplankton growth overall. According to a potential eutrophication assessment model, both the surface water and the water at a depth of 15m were classified as water 1 (poor nutrition). This study provides baseline information including chemical datasets for future pollution monitoring and management programs in this area. Copyright © 2015 Elsevier Ltd. All rights reserved.

  10. A spatially nonselective baseline signal in parietal cortex reflects the probability of a monkey’s success on the current trial

    PubMed Central

    Zhang, Mingsha; Wang, Xiaolan; Goldberg, Michael E.

    2014-01-01

    We recorded the activity of neurons in the lateral intraparietal area of two monkeys while they performed two similar visual search tasks, one difficult, one easy. Each task began with a period of fixation followed by an array consisting of a single capital T and a number of lowercase t’s. The monkey had to find the capital T and report its orientation, upright or inverted, with a hand movement. In the easy task the monkey could explore the array with saccades. In the difficult task the monkey had to continue fixating and find the capital T in the visual periphery. The baseline activity measured during the fixation period, at a time in which the monkey could not know if the impending task would be difficult or easy or where the target would appear, predicted the monkey’s probability of success or failure on the task. The baseline activity correlated inversely with the monkey's recent history of success and directly with the intensity of the response to the search array on the current trial. The baseline activity was unrelated to the monkey’s spatial locus of attention as determined by the location of the cue in a cued visual reaction time task. We suggest that rather than merely reflecting the noise in the system, the baseline signal reflects the cortical manifestation of modulatory state, motivational, or arousal pathways, which determine the efficiency of cortical sensorimotor processing and the quality of the monkey’s performance. PMID:24889623

  11. Historical baselines of coral cover on tropical reefs as estimated by expert opinion

    PubMed Central

    Cheung, William W.L.; Bruno, John F.

    2018-01-01

    Coral reefs are important habitats that represent global marine biodiversity hotspots and provide important benefits to people in many tropical regions. However, coral reefs are becoming increasingly threatened by climate change, overfishing, habitat destruction, and pollution. Historical baselines of coral cover are important to understand how much coral cover has been lost, e.g., to avoid the ‘shifting baseline syndrome’. There are few quantitative observations of coral reef cover prior to the industrial revolution, and therefore baselines of coral reef cover are difficult to estimate. Here, we use expert and ocean-user opinion surveys to estimate baselines of global coral reef cover. The overall mean estimated baseline coral cover was 59% (±19% standard deviation), compared to an average of 58% (±18% standard deviation) estimated by professional scientists. We did not find evidence of the shifting baseline syndrome, whereby respondents who first observed coral reefs more recently report lower estimates of baseline coral cover. These estimates of historical coral reef baseline cover are important for scientists, policy makers, and managers to understand the extent to which coral reefs have become depleted and to set appropriate recovery targets. PMID:29379692

  12. Historical baselines of coral cover on tropical reefs as estimated by expert opinion.

    PubMed

    Eddy, Tyler D; Cheung, William W L; Bruno, John F

    2018-01-01

    Coral reefs are important habitats that represent global marine biodiversity hotspots and provide important benefits to people in many tropical regions. However, coral reefs are becoming increasingly threatened by climate change, overfishing, habitat destruction, and pollution. Historical baselines of coral cover are important to understand how much coral cover has been lost, e.g., to avoid the 'shifting baseline syndrome'. There are few quantitative observations of coral reef cover prior to the industrial revolution, and therefore baselines of coral reef cover are difficult to estimate. Here, we use expert and ocean-user opinion surveys to estimate baselines of global coral reef cover. The overall mean estimated baseline coral cover was 59% (±19% standard deviation), compared to an average of 58% (±18% standard deviation) estimated by professional scientists. We did not find evidence of the shifting baseline syndrome, whereby respondents who first observed coral reefs more recently report lower estimates of baseline coral cover. These estimates of historical coral reef baseline cover are important for scientists, policy makers, and managers to understand the extent to which coral reefs have become depleted and to set appropriate recovery targets.

  13. Baseline Chromatin Modification Levels May Predict ...

    EPA Pesticide Factsheets

    Traditional toxicological paradigms have relied on factors such as age, genotype, and disease status to explain variability in responsiveness to toxicant exposure; however, these are neither sufficient to faithfully identify differentially responsive individuals nor are they modifiable factors that can be leveraged to mitigate the exposure effects. Unlike these factors, the epigenome is dynamic and shaped by an individual's environment. We sought to determine whether baseline levels of specific chromatin modifications correlated with the interindividual variability in their ozone (03)-mediated induction in an air-liquid interface model using primary human bronchial epithelial cells from a panel of 11 donors. We characterized the relationship between the baseline abundance of 6 epigenetic markers with established roles as key regulators of gene expression-histone H3 lysine 4 trimethylation (H3K4me3), H3K27 acetylation (H3K27ac), pan­acetyl H4 (H4ac), histone H3K27 di/trimethylation (H3K27me2/3), unmodified H3, and5-hydroxymethylcytosine (5-hmC)-and the variability in the 03-induced expression of IL-8, IL-6, COX2, and HMOX1. Baseline levels of H3K4me3, H3K27me2/3, and 5-hmC, but not H3K27ac, H4ac, and total H3, correlated with the interindividual variability in 03-mediated induction of HMOX1 and COX2. In contrast, none of the chromatin modifications that we examined correlated with the induction of IL-8 and IL-6. From these findings, we propose an "epigenetic see

  14. Longitudinal change instead of baseline testosterone predicts depressive symptoms.

    PubMed

    Kische, Hanna; Pieper, Lars; Venz, John; Klotsche, Jens; März, Winfried; Koch-Gromus, Uwe; Pittrow, David; Lehnert, Hendrik; Silber, Sigmund; Stalla, G K; Zeiher, Andreas M; Wittchen, Hans-Ulrich; Haring, Robin

    2018-03-01

    The association between total testosterone (T) and depression mostly relies on single sex hormone assessment and remains inconclusive. Thus, we investigated the comparative predictive performance of baseline T and change in T with development of depressive symptoms and incident depressive episodes. We used data from 6493 primary care patients (2653 men and 3840 women) of the DETECT study (Diabetes Cardiovascular Risk-Evaluation: Targets and Essential Data for Commitment of Treatment), including four-year follow-up, repeated immunoassay-based measurement of serum T and depressive symptoms assessed by the Depression Screening Questionnaire (DSQ). Cross-sectional and longitudinal associations of baseline T and one-year change in T with prevalent and incident depression were investigated using age- and multivariable-adjusted regression models. Baseline T showed no association with prevalent or incident depressive symptoms and episodes in both sexes. In men, a positive change in T (higher T at one-year follow-up compared to baseline) was associated with a lower burden of depressive symptoms (β-coefficient per unit change in T: -0.17; 95% CI: -0.31 to -0.04) and lower risk of incident depressive symptoms (odds ratio per unit change in T: 0.84; 95% CI: 0.72-0.98) at four-year follow-up. In women, the association of T change with incident depressive episodes was rendered non-significant after multivariable adjustment. The present study observed a sex-specific inverse association of T change, but not baseline T, with increased depressive symptom burden in men. Future studies should assess longitudinal changes in sex hormone status as predictor of adverse health outcomes related to low T. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Sleep Quality Improvement During Cognitive Behavioral Therapy for Anxiety Disorders.

    PubMed

    Ramsawh, Holly J; Bomyea, Jessica; Stein, Murray B; Cissell, Shadha H; Lang, Ariel J

    2016-01-01

    Despite the ubiquity of sleep complaints among individuals with anxiety disorders, few prior studies have examined whether sleep quality improves during anxiety treatment. The current study examined pre- to posttreatment sleep quality improvement during cognitive behavioral therapy (CBT) for panic disorder (PD; n = 26) or generalized anxiety disorder (GAD; n = 24). Among sleep quality indices, only global sleep quality and sleep latency improved significantly (but modestly) during CBT. Sleep quality improvement was greater for treatment responders, but did not vary by diagnosis. Additionally, poor baseline sleep quality was independently associated with worse anxiety treatment outcome, as measured by higher intolerance of uncertainty. Additional intervention targeting sleep prior to or during CBT for anxiety may be beneficial for poor sleepers.

  16. Quality of life and anxiety in women with breast cancer before and after treatment

    PubMed Central

    Villar, Raquel Rey; Fernández, Salvador Pita; Garea, Carmen Cereijo; Pillado, Mª Teresa Seoane; Barreiro, Vanesa Balboa; Martín, Cristina González

    2017-01-01

    ABSTRACT Objectives: to determine the quality of life and anxiety in patients with breast cancer and the changes they experience after treatments. Method: prospective study. Breast cancer statistics (n=339, confidence=95%, accuracy= ± 5.32%). The quality of life questionnaires (QLQ) used were QLQ C-30 and QLQ Br23, and the State-Trait Anxiety Inventory (STAI) was used for anxiety. A multivariate analysis was performed to identify variables associated with baseline quality of life and anxiety as well as pre- and post-treatment differences. Authorization was obtained from the Ethics Committee, and informed consent was provided by all patients. Results: the baseline quality of life dimensions with the lowest score were future prospects (46.0/100) and sexual enjoyment (55.7/100). The dimensions with the highest score were body image (94.2/100) and role (93.3/100). The most disturbing symptoms were insomnia, fatigue and concern about hair loss. After treatment, the dimensions of physical function, role, body image, financial concerns and symptomatology worsened, whereas emotional function and future prospects improved. Severe anxiety presented as a state (48.6%) and as a trait (18.2%). The highest baseline state anxiety was associated with married-widowed status and anxiolytic medication. The greatest trait anxiety was associated with an inactive work situation, anxiolytic medication, breast swelling and advanced stage at diagnosis. After treatment, anxiety significantly decreased. Conclusions: After treatment, the quality of life score was positively modified, while state and trait anxiety decreased. PMID:29267541

  17. Quality of life and anxiety in women with breast cancer before and after treatment.

    PubMed

    Villar, Raquel Rey; Fernández, Salvador Pita; Garea, Carmen Cereijo; Pillado, Mª Teresa Seoane; Barreiro, Vanesa Balboa; Martín, Cristina González

    2017-12-21

    to determine the quality of life and anxiety in patients with breast cancer and the changes they experience after treatments. prospective study. Breast cancer statistics (n=339, confidence=95%, accuracy= ± 5.32%). The quality of life questionnaires (QLQ) used were QLQ C-30 and QLQ Br23, and the State-Trait Anxiety Inventory (STAI) was used for anxiety. A multivariate analysis was performed to identify variables associated with baseline quality of life and anxiety as well as pre- and post-treatment differences. Authorization was obtained from the Ethics Committee, and informed consent was provided by all patients. the baseline quality of life dimensions with the lowest score were future prospects (46.0/100) and sexual enjoyment (55.7/100). The dimensions with the highest score were body image (94.2/100) and role (93.3/100). The most disturbing symptoms were insomnia, fatigue and concern about hair loss. After treatment, the dimensions of physical function, role, body image, financial concerns and symptomatology worsened, whereas emotional function and future prospects improved. Severe anxiety presented as a state (48.6%) and as a trait (18.2%). The highest baseline state anxiety was associated with married-widowed status and anxiolytic medication. The greatest trait anxiety was associated with an inactive work situation, anxiolytic medication, breast swelling and advanced stage at diagnosis. After treatment, anxiety significantly decreased. After treatment, the quality of life score was positively modified, while state and trait anxiety decreased.

  18. Mechanical Thrombectomy in Elderly Stroke Patients with Mild-to-Moderate Baseline Disability.

    PubMed

    Slawski, Diana E; Salahuddin, Hisham; Shawver, Julie; Kenmuir, Cynthia L; Tietjen, Gretchen E; Korsnack, Andrea; Zaidi, Syed F; Jumaa, Mouhammad A

    2018-04-01

    The number of elderly patients suffering from ischemic stroke is rising. Randomized trials of mechanical thrombectomy (MT) generally exclude patients over the age of 80 years with baseline disability. The aim of this study was to understand the efficacy and safety of MT in elderly patients, many of whom may have baseline impairment. Between January 2015 and April 2017, 96 patients ≥80 years old who underwent MT for stroke were selected for a chart review. The data included baseline characteristics, time to treatment, the rate of revascularization, procedural complications, mortality, and 90-day good outcome defined as a modified Rankin Scale (mRS) score of 0-2 or return to baseline. Of the 96 patients, 50 had mild baseline disability (mRS score 0-1) and 46 had moderate disability (mRS score 2-4). Recanalization was achieved in 84% of the patients, and the rate of symptomatic hemorrhage was 6%. At 90 days, 34% of the patients had a good outcome. There were no significant differences in good outcome between those with mild and those with moderate baseline disability (43 vs. 24%, p = 0.08), between those aged ≤85 and those aged > 85 years (40.8 vs. 26.1%, p = 0.19), and between those treated within and those treated beyond 8 h (39 vs. 20%, p = 0.1). The mortality rate was 38.5% at 90 days. The Alberta Stroke Program Early CT Score (ASPECTS) and the National Institutes of Health Stroke Scale (NIHSS) predicted good outcome regardless of baseline disability ( p < 0.001 and p = 0.009, respectively). Advanced age, baseline disability, and delayed treatment are associated with sub-optimal outcomes after MT. However, redefining good outcome to include return to baseline functioning demonstrates that one-third of this patient population benefits from MT, suggesting the real-life utility of this treatment.

  19. Long-Baseline Neutrino Experiments

    DOE PAGES

    Diwan, M. V.; Galymov, V.; Qian, X.; ...

    2016-10-19

    We review long-baseline neutrino experiments in which neutrinos are detected after traversing macroscopic distances. Over such distances neutrinos have been found to oscillate among flavor states. Experiments with solar, atmospheric, reactor, and accelerator neutrinos have resulted in a coherent picture of neutrino masses and mixing of the three known flavor states. We will summarize the current best knowledge of neutrino parameters and phenomenology with our focus on the evolution of the experimental technique. We will proceed from the rst evidence produced by astrophysical neutrino sources to the current open questions and the goals of future research

  20. 77 FR 26535 - Hope Gas, Inc.; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-04

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR12-23-000] Hope Gas, Inc.; Notice of Baseline Filing Take notice that on April 26, 2012, Hope Gas, Inc. (Hope Gas) submitted a baseline filing of their Statement of Operating Conditions for services provided under Section 311 of the...

  1. 77 FR 31841 - Hope Gas, Inc.; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-30

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR12-23-001] Hope Gas, Inc.; Notice of Baseline Filing Take notice that on May 16, 2012, Hope Gas, Inc. (Hope Gas) submitted a revised baseline filing of their Statement of Operating Conditions for services provided under Section 311 of the...

  2. 75 FR 37786 - Crosstex LIG, LLC; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-30

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR10-40-000] Crosstex LIG, LLC; Notice of Baseline Filing June 23, 2010. Take notice that on June 21, 2010, Crosstex LIG, LLC submitted a baseline filing of its FERC Operating Statement for services provided under Section 311 of the...

  3. 75 FR 33799 - EasTrans, LLC; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-15

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR10-30-000] EasTrans, LLC; Notice of Baseline Filing June 8, 2010. Take notice that on June 4, 2010, EasTrans, LLC submitted a baseline filing of its Statement of Operating Conditions for services provided under section 311 of the...

  4. Piloting laboratory quality system management in six health facilities in Nigeria.

    PubMed

    Mbah, Henry; Ojo, Emmanuel; Ameh, James; Musuluma, Humphrey; Negedu-Momoh, Olubunmi Ruth; Jegede, Feyisayo; Ojo, Olufunmilayo; Uwakwe, Nkem; Ochei, Kingsley; Dada, Michael; Udah, Donald; Chiegil, Robert; Torpey, Kwasi

    2014-01-01

    Achieving accreditation in laboratories is a challenge in Nigeria like in most African countries. Nigeria adopted the World Health Organization Regional Office for Africa Stepwise Laboratory (Quality) Improvement Process Towards Accreditation (WHO/AFRO- SLIPTA) in 2010. We report on FHI360 effort and progress in piloting WHO-AFRO recognition and accreditation preparedness in six health facility laboratories in five different states of Nigeria. Laboratory assessments were conducted at baseline, follow up and exit using the WHO/AFRO- SLIPTA checklist. From the total percentage score obtained, the quality status of laboratories were classified using a zero to five star rating, based on the WHO/AFRO quality improvement stepwise approach. Major interventions include advocacy, capacity building, mentorship and quality improvement projects. At baseline audit, two of the laboratories attained 1- star while the remaining four were at 0- star. At follow up audit one lab was at 1- star, two at 3-star and three at 4-star. At exit audit, four labs were at 4- star, one at 3-star and one at 2-star rating. One laboratory dropped a 'star' at exit audit, while others consistently improved. The two weakest elements at baseline; internal audit (4%) and occurrence/incidence management (15%) improved significantly, with an exit score of 76% and 81% respectively. The elements facility and safety was the major strength across board throughout the audit exercise. This effort resulted in measurable and positive impact on the laboratories. We recommend further improvement towards a formal international accreditation status and scale up of WHO/AFRO- SLIPTA implementation in Nigeria.

  5. Benthic foraminifera baseline assemblages from a coastal nearshore reef complex on the central Great Barrier Reef

    NASA Astrophysics Data System (ADS)

    Johnson, Jamie; Perry, Chris; Smithers, Scott; Morgan, Kyle

    2016-04-01

    Declining water quality due to river catchment modification since European settlement (c. 1850 A.D.) represents a major threat to the health of coral reefs on Australia's Great Barrier Reef (GBR), particularly for those located in the coastal waters of the GBR's inner-shelf. These nearshore reefs are widely perceived to be most susceptible to declining water quality owing to their close proximity to river point sources. Despite this, nearshore reefs have been relatively poorly studied with the impacts and magnitudes of environmental degradation still remaining unclear. This is largely due to ongoing debates concerning the significance of increased sediment yields against naturally high background sedimentary regimes. Benthic foraminifera are increasingly used as tools for monitoring environmental and ecological change on coral reefs. On the GBR, the majority of studies have focussed on the spatial distributions of contemporary benthic foraminiferal assemblages. While baseline assemblages from other environments (e.g. inshore reefs and mangroves) have been described, very few records exist for nearshore reefs. Here, we present preliminary results from the first palaeoecological study of foraminiferal assemblages of nearshore reefs on the central GBR. Cores were recovered from the nearshore reef complex at Paluma Shoals using percussion techniques. Recovery was 100%, capturing the entire Holocene reef sequence of the selected reef structures. Radiocarbon dating and subsequent age-depth modelling techniques were used to identify reef sequences pre-dating European settlement. Benthic foraminifera assemblages were reconstructed from the identified sequences to establish pre-European ecological baselines with the aim of providing a record of foraminiferal distribution during vertical reef accretion and against which contemporary ecological change may be assessed.

  6. Long-term health implications of school quality.

    PubMed

    Dudovitz, Rebecca N; Nelson, Bergen B; Coker, Tumaini R; Biely, Christopher; Li, Ning; Wu, Lynne C; Chung, Paul J

    2016-06-01

    Individual academic achievement is a well-known predictor of adult health, and addressing education inequities may be critical to reducing health disparities. Disparities in school quality are well documented. However, we lack nationally representative studies evaluating the impact of school quality on adult health. We aim to determine whether high school quality predicts adult health outcomes after controlling for baseline health, socio-demographics and individual academic achievement. We analyzed data from 7037 adolescents who attended one of 77 high schools in the Unites States and were followed into adulthood from the National Longitudinal Study of Adolescent to Adult Health. Selected school-level quality measures-average daily attendance, school promotion rate, parental involvement, and teacher experience-were validated based on ability to predict high school graduation and college attendance. Individual adult health outcomes included self-rated health, diagnosis of depression, and having a measured BMI in the obese range. Logistic regressions controlling for socio-demographics, baseline health, health insurance, and individual academic performance demonstrated that school quality significantly predicted all health outcomes. As hypothesized, attending a school with lower average daily attendance predicted lower self-rated health (Adjusted Odds Ratio (AOR) 1.59, p = 0.003) and higher odds of depression diagnosis (AOR 1.35, p = 0.03); and attending a school with higher parent involvement predicted lower odds of obesity (AOR 0.69, p = 0.001). However, attending a school with higher promotion rate also predicted lower self-rated health (AOR1.20, p < 0.001). High school quality may be an important, but complex, social determinant of health. These findings highlight the potential inter-dependence of education and health policy. Copyright © 2016 Elsevier Ltd. All rights reserved.

  7. Topiramate on the quality of life in childhood epilepsy.

    PubMed

    Jung, Da-Eun; Kim, Heung-Dong; Hur, Yun-Jung; Eom, So-Yong

    2011-10-01

    This study evaluated the effect of topiramate (TPM) on the quality of life (QOL) in childhood epilepsy, using the Korean quality of life in childhood epilepsy (K-QOLCE) questionnaire. An open label, prospective, observational study of the families of 664 children with epilepsy from 41 centers was conducted. The parents completed the K-QOLCE at the baseline visit and again 6months after starting TPM treatment. The parents reported the seizure frequency at both assessment dates. Statistically significant improvements in all K-QOLCE domains except social functioning were found at 6months after starting TPM treatment from the baseline-scores (P<0.05). However, improved QOL scores were not dependent on the reduction in seizure frequency. TPM significantly improved QOL in children with epilepsy, suggesting its potential clinical benefits. Copyright © 2010 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.

  8. Scandinavia studies of recent crustal movements and the space geodetic baseline network

    NASA Technical Reports Server (NTRS)

    Anderson, A. J.

    1980-01-01

    A brief review of crustal movements within the Fenno-Scandia shield is given. Results from postglacial studies, projects for measuring active fault regions, and dynamic ocean loading experiments are presented. The 1979 Scandinavian Doppler Campaign Network is discussed. This network includes Doppler translocation baseline determination of future very long baseline interferometry baselines to be measured in Scandinavia. Intercomparison of earlier Doppler translocation measurements with a high precision terrestrial geodetic baseline in Scandinavia has yielded internal agreement of 6 cm over 887 km. This is a precision of better than 1 part in to the 7th power.

  9. Statistical testing of baseline differences in sports medicine RCTs: a systematic evaluation.

    PubMed

    Peterson, Ross L; Tran, Matthew; Koffel, Jonathan; Stovitz, Steven D

    2017-01-01

    The CONSORT (Consolidated Standards of Reporting Trials) statement discourages reporting statistical tests of baseline differences between groups in randomised controlled trials (RCTs). However, this practice is still common in many medical fields. Our aim was to determine the prevalence of this practice in leading sports medicine journals. We conducted a comprehensive search in Medline through PubMed to identify RCTs published in the years 2005 and 2015 from 10 high-impact sports medicine journals. Two reviewers independently confirmed the trial design and reached consensus on which articles contained statistical tests of baseline differences. Our search strategy identified a total of 324 RCTs, with 85 from the year 2005 and 239 from the year 2015. Overall, 64.8% of studies (95% CI (59.6, 70.0)) reported statistical tests of baseline differences; broken down by year, this percentage was 67.1% in 2005 (95% CI (57.1, 77.1)) and 64.0% in 2015 (95% CI (57.9, 70.1)). Although discouraged by the CONSORT statement, statistical testing of baseline differences remains highly prevalent in sports medicine RCTs. Statistical testing of baseline differences can mislead authors; for example, by failing to identify meaningful baseline differences in small studies. Journals that ask authors to follow the CONSORT statement guidelines should recognise that many manuscripts are ignoring the recommendation against statistical testing of baseline differences.

  10. National Cyberethics, Cybersafety, Cybersecurity Baseline Study

    ERIC Educational Resources Information Center

    Education Digest: Essential Readings Condensed for Quick Review, 2009

    2009-01-01

    This article presents findings from a study that explores the nature of the Cyberethics, Cybersafety, and Cybersecurity (C3) educational awareness policies, initiatives, curriculum, and practices currently taking place in the U.S. public and private K-12 educational settings. The study establishes baseline data on C3 awareness, which can be used…

  11. Modeling Nonlinear Errors in Surface Electromyography Due To Baseline Noise: A New Methodology

    PubMed Central

    Law, Laura Frey; Krishnan, Chandramouli; Avin, Keith

    2010-01-01

    The surface electromyographic (EMG) signal is often contaminated by some degree of baseline noise. It is customary for scientists to subtract baseline noise from the measured EMG signal prior to further analyses based on the assumption that baseline noise adds linearly to the observed EMG signal. The stochastic nature of both the baseline and EMG signal, however, may invalidate this assumption. Alternately, “true” EMG signals may be either minimally or nonlinearly affected by baseline noise. This information is particularly relevant at low contraction intensities when signal-to-noise ratios (SNR) may be lowest. Thus, the purpose of this simulation study was to investigate the influence of varying levels of baseline noise (approximately 2 – 40 % maximum EMG amplitude) on mean EMG burst amplitude and to assess the best means to account for signal noise. The simulations indicated baseline noise had minimal effects on mean EMG activity for maximum contractions, but increased nonlinearly with increasing noise levels and decreasing signal amplitudes. Thus, the simple baseline noise subtraction resulted in substantial error when estimating mean activity during low intensity EMG bursts. Conversely, correcting EMG signal as a nonlinear function of both baseline and measured signal amplitude provided highly accurate estimates of EMG amplitude. This novel nonlinear error modeling approach has potential implications for EMG signal processing, particularly when assessing co-activation of antagonist muscles or small amplitude contractions where the SNR can be low. PMID:20869716

  12. Association of Fetal Heart Rate Baseline Change and Neonatal Outcomes.

    PubMed

    Yang, Michael; Stout, Molly J; López, Julia D; Colvin, Ryan; Macones, George A; Cahill, Alison G

    2017-07-01

    Objective  The objective of this study was to describe the incidence of baseline change within normal range during labor and its prediction of neonatal outcomes. Materials and Methods  This was a prospective cohort of singleton, nonanomalous, term neonates with continuous electronic fetal monitoring and normal baseline fetal heart rate throughout the last 2 hours of labor. We determined baseline in 10-minute segments using Eunice Kennedy Shriver National Institute of Child Health and Human Development criteria. We evaluated baseline changes of ≥ 20 and ≥ 30 bpm for association with acidemia (umbilical cord arterial pH ≤ 7.10) and neonatal intensive care unit (NICU) admission. Finally, we performed a sensitivity analysis of normal neonates, excluding those with acidemia, NICU admission, or 5-minute Apgar < 4. Results  Among all neonates ( n  = 3,021), 1,267 (41.9%) had change ≥ 20 bpm; 272 (9.0%) had ≥ 30 bpm. Among normal neonates ( n  = 2,939), 1,221 (41.5%) had change ≥20 bpm. Acidemia was not associated with baseline change of any direction or magnitude. NICU admission was associated with decrease ≥ 20 bpm (adjusted odds ratio [aOR]: 2.93; 95% confidence interval [CI]: 1.19 - 7.21) or any direction ≥ 20 bpm (aOR: 4.06; 95% CI: 1.46-11.29). For decrease ≥ 20 bpm, sensitivity and specificity were 40.0 and 81.7%; for any direction ≥ 20 bpm, 75.0 and 58.3%. Conclusion  Changes of normal baseline are common in term labor and poorly predict morbidity, regardless of direction or magnitude. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  13. Linear MALDI-ToF simultaneous spectrum deconvolution and baseline removal.

    PubMed

    Picaud, Vincent; Giovannelli, Jean-Francois; Truntzer, Caroline; Charrier, Jean-Philippe; Giremus, Audrey; Grangeat, Pierre; Mercier, Catherine

    2018-04-05

    Thanks to a reasonable cost and simple sample preparation procedure, linear MALDI-ToF spectrometry is a growing technology for clinical microbiology. With appropriate spectrum databases, this technology can be used for early identification of pathogens in body fluids. However, due to the low resolution of linear MALDI-ToF instruments, robust and accurate peak picking remains a challenging task. In this context we propose a new peak extraction algorithm from raw spectrum. With this method the spectrum baseline and spectrum peaks are processed jointly. The approach relies on an additive model constituted by a smooth baseline part plus a sparse peak list convolved with a known peak shape. The model is then fitted under a Gaussian noise model. The proposed method is well suited to process low resolution spectra with important baseline and unresolved peaks. We developed a new peak deconvolution procedure. The paper describes the method derivation and discusses some of its interpretations. The algorithm is then described in a pseudo-code form where the required optimization procedure is detailed. For synthetic data the method is compared to a more conventional approach. The new method reduces artifacts caused by the usual two-steps procedure, baseline removal then peak extraction. Finally some results on real linear MALDI-ToF spectra are provided. We introduced a new method for peak picking, where peak deconvolution and baseline computation are performed jointly. On simulated data we showed that this global approach performs better than a classical one where baseline and peaks are processed sequentially. A dedicated experiment has been conducted on real spectra. In this study a collection of spectra of spiked proteins were acquired and then analyzed. Better performances of the proposed method, in term of accuracy and reproductibility, have been observed and validated by an extended statistical analysis.

  14. The results of a randomized trial of a quality improvement intervention in the care of patients with heart failure. The MISCHF Study Investigators.

    PubMed

    Philbin, E F; Rocco, T A; Lindenmuth, N W; Ulrich, K; McCall, M; Jenkins, P L

    2000-10-15

    Quality improvement and disease management programs for heart failure have improved quality of care and patient outcomes at large tertiary care hospitals. The purpose of this study was to measure the effects of a regional, multihospital, collaborative quality improvement intervention on care and outcomes in heart failure in community hospitals. This randomized controlled study included 10 acute care community hospitals in upstate New York. After a baseline period, 5 hospitals were randomly assigned to receive a multifaceted quality improvement intervention (n = 762 patients during the baseline period; n = 840 patients postintervention), while 5 were assigned to a "usual care" control (n = 640 patients during the baseline period; n = 664 patients postintervention). Quality of care was determined using explicit criteria by reviewing the charts of consecutive patients hospitalized with the primary diagnosis of heart failure during the baseline period and again in the postintervention period. Clinical outcomes included hospital length of stay and charges, in-hospital and 6-month mortality, hospital readmission, and quality of life measured after discharge. Patients had similar characteristics in the baseline and postintervention phases in the intervention and control groups. Using hospital-level analyses, the intervention had mixed effects on 5 quality-of-care markers that were not statistically significant. The mean of the average length of stay among hospitals decreased from 8.0 to 6.2 days in the intervention group, with a smaller decline in mean length of stay in the control group (7.7 to 7.0 days). The net effects of the intervention were nonsignificant changes in length of stay of -1.1 days (95% confidence interval [CI]: -2.9 to 0.7 days, P = 0.18) and in hospital charges of -$817 (95% CI: -$2560 to $926, P = 0.31). There were small and nonsignificant effects on mortality, hospital readmission, and quality of life. The incremental effect of regional collaboration

  15. Status of fish communities in the Rio Grande, Big Bend National Park, Texas - comparison before and after Spring 2003 period of low flow

    USGS Publications Warehouse

    Moring, J. Bruce

    2005-01-01

    During 2003–04 the U.S. Geological Survey, in cooperation with the National Park Service, re-evaluated the status of fish communities in three reaches of the Rio Grande in Big Bend National Park that originally were evaluated when the three reaches were established for study in 1999. The objective was to determine whether there were measurable differences between 1999 and 2003–04 (referred to as 2004) fish community status that likely are attributable to a rare 58-day period of low flow (less than 1 cubic meter per second) in spring 2003 at the Johnson Ranch gaging station on the Rio Grande in Big Bend National Park. The total number of fish species collected at all three sites (Boquillas, Johnson Ranch, and Santa Elena) in 1999 was greater than in 2004. The number of fish species collected at the Boquillas site in 1999 (10) was twice that collected in 2004; the number of species collected at the Johnson Ranch site in 1999 (nine) was almost twice that collected in 2004 (five). In contrast, the numbers at the Santa Elena site were nearly the same, 15 species in 1999, 14 in 2004. Percent community similarity for the Boquillas site is 8.04, for the Johnson Ranch site, 6.65, and for the Santa Elena site, 47.6, which indicates considerably more similarity between the 1999 and 2004 fish communities at the Santa Elena site than for the Boquillas and Johnson Ranch sites. At the Boquillas and Johnson Ranch sites, the fish communities shifted from small minnow (Cyprinidae) dominated in 1999 to largely gar (Lepisosteidae) and catfish (Ictaluridae) dominated in 2004. In contrast, no such shift occurred at the Santa Elena site between 1999 and 2004. Differences in flow conditions between the two downstream sites and the Santa Elena site might account for the dissimilar findings. The findings of the study provide some evidence that the spring 2003 period of low flow affected fish communities, but the findings are not definitive as other factors such as increased salinity

  16. Water Quality Assessment of Ayeyarwady River in Myanmar

    NASA Astrophysics Data System (ADS)

    Thatoe Nwe Win, Thanda; Bogaard, Thom; van de Giesen, Nick

    2015-04-01

    Myanmar's socio-economic activities, urbanisation, industrial operations and agricultural production have increased rapidly in recent years. With the increase of socio-economic development and climate change impacts, there is an increasing threat on quantity and quality of water resources. In Myanmar, some of the drinking water coverage still comes from unimproved sources including rivers. The Ayeyarwady River is the main river in Myanmar draining most of the country's area. The use of chemical fertilizer in the agriculture, the mining activities in the catchment area, wastewater effluents from the industries and communities and other development activities generate pollutants of different nature. Therefore water quality monitoring is of utmost importance. In Myanmar, there are many government organizations linked to water quality management. Each water organization monitors water quality for their own purposes. The monitoring is haphazard, short term and based on individual interest and the available equipment. The monitoring is not properly coordinated and a quality assurance programme is not incorporated in most of the work. As a result, comprehensive data on the water quality of rivers in Myanmar is not available. To provide basic information, action is needed at all management levels. The need for comprehensive and accurate assessments of trends in water quality has been recognized. For such an assessment, reliable monitoring data are essential. The objective of our work is to set-up a multi-objective surface water quality monitoring programme. The need for a scientifically designed network to monitor the Ayeyarwady river water quality is obvious as only limited and scattered data on water quality is available. However, the set-up should also take into account the current socio-economic situation and should be flexible to adjust after first years of monitoring. Additionally, a state-of-the-art baseline river water quality sampling program is required which

  17. Evaluation of very long baseline interferometry atmospheric modeling improvements

    NASA Technical Reports Server (NTRS)

    Macmillan, D. S.; Ma, C.

    1994-01-01

    We determine the improvement in baseline length precision and accuracy using new atmospheric delay mapping functions and MTT by analyzing the NASA Crustal Dynamics Project research and development (R&D) experiments and the International Radio Interferometric Surveying (IRIS) A experiments. These mapping functions reduce baseline length scatter by about 20% below that using the CfA2.2 dry and Chao wet mapping functions. With the newer mapping functions, average station vertical scatter inferred from observed length precision (given by length repeatabilites) is 11.4 mm for the 1987-1990 monthly R&D series of experiments and 5.6 mm for the 3-week-long extended research and development experiment (ERDE) series. The inferred monthly R&D station vertical scatter is reduced by 2 mm or by 7 mm is a root-sum-square (rss) sense. Length repeatabilities are optimum when observations below a 7-8 deg elevation cutoff are removed from the geodetic solution. Analyses of IRIS-A data from 1984 through 1991 and the monthly R&D experiments both yielded a nonatmospheric unmodeled station vertical error or about 8 mm. In addition, analysis of the IRIS-A exeriments revealed systematic effects in the evolution of some baseline length measurements. The length rate of change has an apparent acceleration, and the length evolution has a quasi-annual signature. We show that the origin of these effects is unlikely to be related to atmospheric modeling errors. Rates of change of the transatlantic Westford-Wettzell and Richmond-Wettzell baseline lengths calculated from 1988 through 1991 agree with the NUVEL-1 plate motion model (Argus and Gordon, 1991) to within 1 mm/yr. Short-term (less than 90 days) variations of IRIS-A baseline length measurements contribute more than 90% of the observed scatter about a best fit line, and this short-term scatter has large variations on an annual time scale.

  18. Baseline Motivation Type as a Predictor of Dropout in a Healthy Eating Text Messaging Program.

    PubMed

    Coa, Kisha; Patrick, Heather

    2016-09-29

    Growing evidence suggests that text messaging programs are effective in facilitating health behavior change. However, high dropout rates limit the potential effectiveness of these programs. This paper describes patterns of early dropout in the HealthyYou text (HYTxt) program, with a focus on the impact of baseline motivation quality on dropout, as characterized by Self-Determination Theory (SDT). This analysis included 193 users of HYTxt, a diet and physical activity text messaging intervention developed by the US National Cancer Institute. Descriptive statistics were computed, and logistic regression models were run to examine the association between baseline motivation type and early program dropout. Overall, 43.0% (83/193) of users dropped out of the program; of these, 65.1% (54/83; 28.0% of all users) did so within the first 2 weeks. Users with higher autonomous motivation had significantly lower odds of dropping out within the first 2 weeks. A one unit increase in autonomous motivation was associated with lower odds (odds ratio 0.44, 95% CI 0.24-0.81) of early dropout, which persisted after adjusting for level of controlled motivation. Applying SDT-based strategies to enhance autonomous motivation might reduce early dropout rates, which can improve program exposure and effectiveness.

  19. Change in Quality of Life after Rehabilitation: Prognostic Factors for Visually Impaired Adults

    ERIC Educational Resources Information Center

    Langelaan, Maaike; de Boer, Michiel R.; van Nispen, Ruth M. A.; Wouters, Bill; Moll, Annette C.; van Rens, Ger H. M. B.

    2009-01-01

    The overall aim of rehabilitation for visually impaired adults is to improve the quality of life and (societal) participation. The objectives of this study were to obtain the short-term and long-term outcome of a comprehensive rehabilitation programme on quality of life for visually impaired adults, and prognostic baseline factors responsible for…

  20. Leveraging probabilistic peak detection to estimate baseline drift in complex chromatographic samples.

    PubMed

    Lopatka, Martin; Barcaru, Andrei; Sjerps, Marjan J; Vivó-Truyols, Gabriel

    2016-01-29

    Accurate analysis of chromatographic data often requires the removal of baseline drift. A frequently employed strategy strives to determine asymmetric weights in order to fit a baseline model by regression. Unfortunately, chromatograms characterized by a very high peak saturation pose a significant challenge to such algorithms. In addition, a low signal-to-noise ratio (i.e. s/n<40) also adversely affects accurate baseline correction by asymmetrically weighted regression. We present a baseline estimation method that leverages a probabilistic peak detection algorithm. A posterior probability of being affected by a peak is computed for each point in the chromatogram, leading to a set of weights that allow non-iterative calculation of a baseline estimate. For extremely saturated chromatograms, the peak weighted (PW) method demonstrates notable improvement compared to the other methods examined. However, in chromatograms characterized by low-noise and well-resolved peaks, the asymmetric least squares (ALS) and the more sophisticated Mixture Model (MM) approaches achieve superior results in significantly less time. We evaluate the performance of these three baseline correction methods over a range of chromatographic conditions to demonstrate the cases in which each method is most appropriate. Copyright © 2016 Elsevier B.V. All rights reserved.

  1. Synthesizing SMOS Zero-Baselines with Aquarius Brightness Temperature Simulator

    NASA Technical Reports Server (NTRS)

    Colliander, A.; Dinnat, E.; Le Vine, D.; Kainulainen, J.

    2012-01-01

    SMOS [1] and Aquarius [2] are ESA and NASA missions, respectively, to make L-band measurements from the Low Earth Orbit. SMOS makes passive measurements whereas Aquarius measures both passive and active. SMOS was launched in November 2009 and Aquarius in June 2011.The scientific objectives of the missions are overlapping: both missions aim at mapping the global Sea Surface Salinity (SSS). Additionally, SMOS mission produces soil moisture product (however, Aquarius data will eventually be used for retrieving soil moisture too). The consistency of the brightness temperature observations made by the two instruments is essential for long-term studies of SSS and soil moisture. For resolving the consistency, the calibration of the instruments is the key. The basis of the SMOS brightness temperature level is the measurements performed with the so-called zero-baselines [3]; SMOS employs an interferometric measurement technique which forms a brightness temperature image from several baselines constructed by combination of multiple receivers in an array; zero-length baseline defines the overall brightness temperature level. The basis of the Aquarius brightness temperature level is resolved from the brightness temperature simulator combined with ancillary data such as antenna patterns and environmental models [4]. Consistency between the SMOS zero-baseline measurements and the simulator output would provide a robust basis for establishing the overall comparability of the missions.

  2. Atmospheric pressure loading parameters from very long baseline interferometry observations

    NASA Technical Reports Server (NTRS)

    Macmillan, D. S.; Gipson, John M.

    1994-01-01

    Atmospheric mass loading produces a primarily vertical displacement of the Earth's crust. This displacement is correlated with surface pressure and is large enough to be detected by very long baseline interferometry (VLBI) measurements. Using the measured surface pressure at VLBI stations, we have estimated the atmospheric loading term for each station location directly from VLBI data acquired from 1979 to 1992. Our estimates of the vertical sensitivity to change in pressure range from 0 to -0.6 mm/mbar depending on the station. These estimates agree with inverted barometer model calculations (Manabe et al., 1991; vanDam and Herring, 1994) of the vertical displacement sensitivity computed by convolving actual pressure distributions with loading Green's functions. The pressure sensitivity tends to be smaller for stations near the coast, which is consistent with the inverted barometer hypothesis. Applying this estimated pressure loading correction in standard VLBI geodetic analysis improves the repeatability of estimated lengths of 25 out of 37 baselines that were measured at least 50 times. In a root-sum-square (rss) sense, the improvement generally increases with baseline length at a rate of about 0.3 to 0.6 ppb depending on whether the baseline stations are close to the coast. For the 5998-km baseline from Westford, Massachusetts, to Wettzell, Germany, the rss improvement is about 3.6 mm out of 11.0 mm. The average rss reduction of the vertical scatter for inland stations ranges from 2.7 to 5.4 mm.

  3. Network meta-analysis of disconnected networks: How dangerous are random baseline treatment effects?

    PubMed

    Béliveau, Audrey; Goring, Sarah; Platt, Robert W; Gustafson, Paul

    2017-12-01

    In network meta-analysis, the use of fixed baseline treatment effects (a priori independent) in a contrast-based approach is regularly preferred to the use of random baseline treatment effects (a priori dependent). That is because, often, there is not a need to model baseline treatment effects, which carry the risk of model misspecification. However, in disconnected networks, fixed baseline treatment effects do not work (unless extra assumptions are made), as there is not enough information in the data to update the prior distribution on the contrasts between disconnected treatments. In this paper, we investigate to what extent the use of random baseline treatment effects is dangerous in disconnected networks. We take 2 publicly available datasets of connected networks and disconnect them in multiple ways. We then compare the results of treatment comparisons obtained from a Bayesian contrast-based analysis of each disconnected network using random normally distributed and exchangeable baseline treatment effects to those obtained from a Bayesian contrast-based analysis of their initial connected network using fixed baseline treatment effects. For the 2 datasets considered, we found that the use of random baseline treatment effects in disconnected networks was appropriate. Because those datasets were not cherry-picked, there should be other disconnected networks that would benefit from being analyzed using random baseline treatment effects. However, there is also a risk for the normality and exchangeability assumption to be inappropriate in other datasets even though we have not observed this situation in our case study. We provide code, so other datasets can be investigated. Copyright © 2017 John Wiley & Sons, Ltd.

  4. Baseline adjustments for binary data in repeated cross-sectional cluster randomized trials.

    PubMed

    Nixon, R M; Thompson, S G

    2003-09-15

    Analysis of covariance models, which adjust for a baseline covariate, are often used to compare treatment groups in a controlled trial in which individuals are randomized. Such analysis adjusts for any baseline imbalance and usually increases the precision of the treatment effect estimate. We assess the value of such adjustments in the context of a cluster randomized trial with repeated cross-sectional design and a binary outcome. In such a design, a new sample of individuals is taken from the clusters at each measurement occasion, so that baseline adjustment has to be at the cluster level. Logistic regression models are used to analyse the data, with cluster level random effects to allow for different outcome probabilities in each cluster. We compare the estimated treatment effect and its precision in models that incorporate a covariate measuring the cluster level probabilities at baseline and those that do not. In two data sets, taken from a cluster randomized trial in the treatment of menorrhagia, the value of baseline adjustment is only evident when the number of subjects per cluster is large. We assess the generalizability of these findings by undertaking a simulation study, and find that increased precision of the treatment effect requires both large cluster sizes and substantial heterogeneity between clusters at baseline, but baseline imbalance arising by chance in a randomized study can always be effectively adjusted for. Copyright 2003 John Wiley & Sons, Ltd.

  5. Reducing contrast-induced acute kidney injury using a regional multicenter quality improvement intervention.

    PubMed

    Brown, Jeremiah R; Solomon, Richard J; Sarnak, Mark J; McCullough, Peter A; Splaine, Mark E; Davies, Louise; Ross, Cathy S; Dauerman, Harold L; Stender, Janette L; Conley, Sheila M; Robb, John F; Chaisson, Kristine; Boss, Richard; Lambert, Peggy; Goldberg, David J; Lucier, Deborah; Fedele, Frank A; Kellett, Mirle A; Horton, Susan; Phillips, William J; Downs, Cynthia; Wiseman, Alan; MacKenzie, Todd A; Malenka, David J

    2014-09-01

    Contrast-induced acute kidney injury (CI-AKI) is associated with increased morbidity and mortality after percutaneous coronary interventions and is a patient safety objective of the National Quality Forum. However, no formal quality improvement program to prevent CI-AKI has been conducted. Therefore, we sought to determine whether a 6-year regional multicenter quality improvement intervention could reduce CI-AKI after percutaneous coronary interventions. We conducted a prospective multicenter quality improvement study to prevent CI-AKI (serum creatinine increase ≥0.3 mg/dL within 48 hours or ≥50% during hospitalization) among 21 067 nonemergent patients undergoing percutaneous coronary interventions at 10 hospitals between 2007 and 2012. Six intervention hospitals participated in the quality improvement intervention. Two hospitals with significantly lower baseline rates of CI-AKI, which served as benchmark sites and were used to develop the intervention, and 2 hospitals not receiving the intervention were used as controls. Using time series analysis and multilevel poisson regression clustering to the hospital level, we calculated adjusted risk ratios for CI-AKI comparing the intervention period to baseline. Adjusted rates of CI-AKI were significantly reduced in hospitals receiving the intervention by 21% (risk ratio, 0.79; 95% confidence interval: 0.67-0.93; P=0.005) for all patients and by 28% in patients with baseline estimated glomerular filtration rate <60 mL/min per 1.73 m(2) (risk ratio, 0.72; 95% confidence interval: 0.56-0.91; P=0.007). Benchmark hospitals had no significant changes in CI-AKI. Key qualitative system factors associated with improvement included multidisciplinary teams, limiting contrast volume, standardized fluid orders, intravenous fluid bolus, and patient education about oral hydration. Simple cost-effective quality improvement interventions can prevent ≤1 in 5 CI-AKI events in patients with undergoing nonemergent percutaneous

  6. An Automatic Baseline Regulation in a Highly Integrated Receiver Chip for JUNO

    NASA Astrophysics Data System (ADS)

    Muralidharan, P.; Zambanini, A.; Karagounis, M.; Grewing, C.; Liebau, D.; Nielinger, D.; Robens, M.; Kruth, A.; Peters, C.; Parkalian, N.; Yegin, U.; van Waasen, S.

    2017-09-01

    This paper describes the data processing unit and an automatic baseline regulation of a highly integrated readout chip (Vulcan) for JUNO. The chip collects data continuously at 1 Gsamples/sec. The Primary data processing which is performed in the integrated circuit can aid to reduce the memory and data processing efforts in the subsequent stages. In addition, a baseline regulator compensating a shift in the baseline is described.

  7. The dermatology life quality index as a means to assess life quality in patients with different scar types.

    PubMed

    Reinholz, M; Poetschke, J; Schwaiger, H; Epple, A; Ruzicka, T; Gauglitz, G G

    2015-11-01

    Measuring quality of life through questionnaires is a common method to evaluate the impact of different afflictions on the patient's well-being, especially in the field of dermatology where appearance changing afflictions are common. A variety of questionnaires has been used to distinguish different skin conditions like psoriasis, atopic dermatitis and scars. Using the Dermatology Life Quality Index (DLQI), we investigated different scar types regarding their impact on quality of life. We assessed the quality of life in 130 patients presenting to our outpatient scar clinic for the first time using the DLQI. Scars were analysed according to their clinical appearance (physiological scars, keloids, hypertrophic scars, atrophic scars, self-harm scars). Physiological scars were established as a baseline for further comparison between groups. Patients in the physiological scar group scored a mean DLQI score of 2.07 ± 3.56, patients in the keloid-, hypertrophic scar-, atrophic scar- and self-harm scar group scored values of 6.06 ± 4.00, 2.53 ± 2.48, 7.26 ± 6.72 and 12.00 ± 3.85 respectively. When compared to the baseline group the difference in the overall score for keloids was +3.99 (P < 0.001), hypertrophic scars scored +0.45 (ns), atrophic scars +5.19 (P < 0.01) and self-harm scars +9.93 (P < 0.001). Using the DLQI, we could demonstrate that different subsets of pathological scars do affect patients in a different magnitude. The DLQI provides a promising adjunct for quantifying the quality of life in patients suffering from keloids, atrophic- and self-harm scars and may constitute an interesting additional tool for monitoring the progress of scar treatments. © 2015 European Academy of Dermatology and Venereology.

  8. 48 CFR 34.202 - Integrated Baseline Reviews.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Integrated Baseline... SPECIAL CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 34.202... inherent risks in offerors'/contractors' performance plans and the underlying management control systems...

  9. 48 CFR 34.202 - Integrated Baseline Reviews.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Integrated Baseline... SPECIAL CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 34.202... inherent risks in offerors'/contractors' performance plans and the underlying management control systems...

  10. 48 CFR 34.202 - Integrated Baseline Reviews.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Integrated Baseline... SPECIAL CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 34.202... inherent risks in offerors'/contractors' performance plans and the underlying management control systems...

  11. 48 CFR 1034.202 - Integrated Baseline Reviews.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... which the management process provides effective and integrated technical/schedule/cost planning and... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Integrated Baseline... SPECIAL CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 1034.202...

  12. Baseline biopsychosocial determinants of telomere length and 6-year attrition rate.

    PubMed

    Révész, Dóra; Milaneschi, Yuri; Terpstra, Erik M; Penninx, Brenda W J H

    2016-05-01

    Short leukocyte telomere length (TL) and accelerated telomere attrition have been associated with various deleterious health outcomes, although their determinants have not been explored collectively in a large-scale study. Leukocyte TL was measured (baseline N=2936; 6-year follow-up N=1860) in participants (18-65 years) from the NESDA study. Baseline determinants of TL included sociodemographics, lifestyle, chronic diseases, psychosocial stressors, and metabolic and physiological stress markers. Multivariate linear regression models were used to examine the associations between these determinants and (1) baseline TL, and (2) 6-year TL change. Multinomial logistic regression analyses were used to examine the predictors of telomere attrition and lengthening, as compared to stable TL. Short baseline TL was associated with older age, male sex, non-European ethnicity, cigarette smoking, recent life events, and higher triglycerides, glucose and pre-ejection period (R(2)=11.3%). The 6-year telomere attrition was inversely associated with baseline TL (R(2)=51.6%); also older age, long sleep, not having a partner, high childhood trauma index, and gastrointestinal disease were associated with 6-year TL attrition (additional R(2)=3.7%). Telomere attrition seemed to have slightly more predictors than lengthening. Sociodemographic, lifestyle, psychosocial stress and metabolic and physiological stress factors are cross-sectionally linked with TL. Telomere attrition over six years was strongly associated with baseline TL, suggesting an internal homeostatic influence. Modulation of the identified determinants may become target of future studies to promote telomere maintenance and healthy aging. Copyright © 2016 Elsevier Ltd. All rights reserved.

  13. Measuring continuous baseline covariate imbalances in clinical trial data

    PubMed Central

    Ciolino, Jody D.; Martin, Renee’ H.; Zhao, Wenle; Hill, Michael D.; Jauch, Edward C.; Palesch, Yuko Y.

    2014-01-01

    This paper presents and compares several methods of measuring continuous baseline covariate imbalance in clinical trial data. Simulations illustrate that though the t-test is an inappropriate method of assessing continuous baseline covariate imbalance, the test statistic itself is a robust measure in capturing imbalance in continuous covariate distributions. Guidelines to assess effects of imbalance on bias, type I error rate, and power for hypothesis test for treatment effect on continuous outcomes are presented, and the benefit of covariate-adjusted analysis (ANCOVA) is also illustrated. PMID:21865270

  14. Mercury exposure may suppress baseline corticosterone levels in juvenile birds

    USGS Publications Warehouse

    Herring, Garth; Ackerman, Joshua T.; Herzog, Mark P.

    2012-01-01

    Mercury exposure has been associated with a wide variety of negative reproductive responses in birds, however few studies have examined the potential for chick impairment via the hypothalamic-pituitary-adrenal (HPA) axis. The HPA axis regulates corticosterone levels during periods of stress. We examined the relationship between baseline fecal corticosterone metabolite concentrations and mercury concentrations in down feathers of recently hatched (Sterna forsteri) chicks in San Francisco Bay, California. Baseline fecal corticosterone metabolite concentrations were negatively correlated with mercury concentrations in blood of older chicks (decreasing by 81% across the range of observed mercury concentrations) while accounting for positive correlations between corticosterone concentrations and number of fledgling chicks within the colony and chick age. In recently hatched chicks, baseline fecal corticosterone metabolite concentrations were weakly negatively correlated with mercury concentrations in down feathers (decreasing by 45% across the range of observed mercury concentrations) while accounting for stronger positive correlations between corticosterone concentrations and colony nest abundance and date. These results indicate that chronic mercury exposure may suppress baseline corticosterone concentrations in tern chicks and suggests that a juvenile bird's ability to respond to stress may be reduced via the downregulation of the HPA axis.

  15. 77 FR 28373 - Liberty Energy (Midstates) Corp.; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-14

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR12-24-000] Liberty Energy (Midstates) Corp.; Notice of Baseline Filing Take notice that on April 30, 2012, Liberty Energy (Midstates) Corp. submitted a baseline filing of their Statement of Operating Conditions for services provided...

  16. 75 FR 74706 - Washington 10 Storage Corporation; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-01

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR10-37-002] Washington 10 Storage Corporation; Notice of Baseline Filing November 23, 2010. Take notice that on November 19, 2010, Washington 10 Storage Corporation submitted a revised baseline filing of its Statement of Operating...

  17. 75 FR 63166 - Southern California Gas Company; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-14

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR10-135-001] Southern California Gas Company; Notice of Baseline Filing October 6, 2010. Take notice that on October 4, 2010, Southern California Gas Company submitted a revised baseline filing of its Statement of Operating...

  18. Differential Susceptibility and the Early Development of Aggression: Interactive Effects of Respiratory Sinus Arrhythmia and Environmental Quality

    PubMed Central

    Eisenberg, Nancy; Sulik, Michael J.; Spinrad, Tracy L.; Edwards, Alison; Eggum, Natalie D.; Liew, Jeffrey; Sallquist, Julie; Popp, Tierney K.; Smith, Cynthia L.; Hart, Daniel

    2012-01-01

    The purpose of the current study was to predict the development of aggressive behavior from young children’s respiratory sinus arrhythmia (RSA) and environmental quality. In a longitudinal sample of 213 children, baseline RSA, RSA suppression in response to a film of crying babies, and a composite measure of environmental quality (incorporating socioeconomic status and marital adjustment) were measured, and parent-reported aggression was assessed from 18 to 54 months of age. Predictions based on biological sensitivity-to-context/differential susceptibility and diathesis-stress models, as well as potential moderation by child sex, were examined. The interaction of baseline RSA with environmental quality predicted the development (slope) and 54-month intercept of mothers’ reports of aggression. For girls only, the interaction between baseline RSA and environmental quality predicted the 18-month intercept of fathers’ reports. In general, significant negative relations between RSA and aggression were found primarily at high levels of environmental quality. In addition, we found a significant Sex × RSA interaction predicting the slope and 54-month intercept of fathers’ reports of aggression, such that RSA was negatively related to aggression for boys but not for girls. Contrary to predictions, no significant main effects or interactions were found for RSA suppression. The results provide mixed but not full support for differential susceptibility theory and provide little support for the diathesis-stress model. PMID:22182294

  19. Southwest principal aquifers regional ground-water quality assessment

    USGS Publications Warehouse

    Anning, D.W.; Thiros, Susan A.; Bexfield, L.M.; McKinney, T.S.; Green, J.M.

    2009-01-01

    The National Water-Quality Assessment (NAWQA) Program of the U.S. Geological Survey is conducting a regional analysis of water quality in the principal aquifers in the southwestern United States. The Southwest Principal Aquifers (SWPA) study is building a better understanding of the susceptibility and vulnerability of basin-fill aquifers in the region to ground-water contamination by synthesizing the baseline knowledge of ground-water quality conditions in 15 basins previously studied by the NAWQA Program. The improved understanding of aquifer susceptibility and vulnerability to contamination is assisting in the development of tools that water managers can use to assess and protect the quality of ground-water resources. This fact sheet provides an overview of the basin-fill aquifers in the southwestern United States and description of the completed and planned regional analyses of ground-water quality being performed by the SWPA study.

  20. Health perceptions and clinical characteristics of relapsing-remitting multiple sclerosis patients: baseline data from an international clinical trial.

    PubMed

    Robinson, D; Zhao, N; Gathany, T; Kim, L-L; Cella, D; Revicki, D

    2009-05-01

    Baseline clinical and health-related quality of life (HRQoL) data from a phase 2, multi-site, international, randomized, controlled trial were analyzed to: (1) characterize the health status of patients with relapsing-remitting multiple sclerosis (RRMS), (2) explore cross-sectional relationships between HRQoL and clinical measures, and (3) evaluate differences in HRQoL scores for subsequent validation as minimally important differences (MID). www.clinicaltrials.gov, NCT00207727. Baseline clinical and HRQoL data were selected and analyzed. HRQoL questionnaires included the Short Form-36 (SF-36), Fatigue Severity Scale (FSS), a Patient Assessment of multiple sclerosis (MS) Impact (PAMSI), and MS-specific symptom scales for Bladder and Bowel Control, Cognition, and Sexual Satisfaction. Standard summary statistics described the population while Pearson and Spearman correlations evaluated the baseline association between HRQoL and clinical measures. Cross-sectional estimates of MID in HRQoL scores were derived using several clinical anchors, the PAMSI, and two tests: Tukey multiple comparisons and adjacent mean difference. Patients (n = 249) had a mean age of 39.0 (Standard deviation, SD = 10.5), 70% were female, 63% resided in Europe, and 96% were Caucasian. Baseline median Expanded Disability Severity Scale (EDSS) was 2.5 (range = 0.0-6.5); median disease duration was 1.9 years (range = 0.1-33.6). The worst baseline mean (normalized) SF-36 scores were for General Health (39.9), Role Physical (40.4), Physical Functioning (41.0), and Vitality (42.7). The worst MS symptom mean scores were for Cognition (6.3) and FSS (4.4). Fatigue scores indicated substantial burden and were consistent with SF-36 Vitality results. Baseline HRQoL scores (SF-36, FSS, MS symptom scales) correlated most with EDSS, Multiple Sclerosis Functional Composite (MSFC), age and disease duration. Lesion count and pre-baseline relapse rate had no meaningful association with HRQoL or other clinical

  1. Change Analysis in Structural Laser Scanning Point Clouds: The Baseline Method

    PubMed Central

    Shen, Yueqian; Lindenbergh, Roderik; Wang, Jinhu

    2016-01-01

    A method is introduced for detecting changes from point clouds that avoids registration. For many applications, changes are detected between two scans of the same scene obtained at different times. Traditionally, these scans are aligned to a common coordinate system having the disadvantage that this registration step introduces additional errors. In addition, registration requires stable targets or features. To avoid these issues, we propose a change detection method based on so-called baselines. Baselines connect feature points within one scan. To analyze changes, baselines connecting corresponding points in two scans are compared. As feature points either targets or virtual points corresponding to some reconstructable feature in the scene are used. The new method is implemented on two scans sampling a masonry laboratory building before and after seismic testing, that resulted in damages in the order of several centimeters. The centres of the bricks of the laboratory building are automatically extracted to serve as virtual points. Baselines connecting virtual points and/or target points are extracted and compared with respect to a suitable structural coordinate system. Changes detected from the baseline analysis are compared to a traditional cloud to cloud change analysis demonstrating the potential of the new method for structural analysis. PMID:28029121

  2. Change Analysis in Structural Laser Scanning Point Clouds: The Baseline Method.

    PubMed

    Shen, Yueqian; Lindenbergh, Roderik; Wang, Jinhu

    2016-12-24

    A method is introduced for detecting changes from point clouds that avoids registration. For many applications, changes are detected between two scans of the same scene obtained at different times. Traditionally, these scans are aligned to a common coordinate system having the disadvantage that this registration step introduces additional errors. In addition, registration requires stable targets or features. To avoid these issues, we propose a change detection method based on so-called baselines. Baselines connect feature points within one scan. To analyze changes, baselines connecting corresponding points in two scans are compared. As feature points either targets or virtual points corresponding to some reconstructable feature in the scene are used. The new method is implemented on two scans sampling a masonry laboratory building before and after seismic testing, that resulted in damages in the order of several centimeters. The centres of the bricks of the laboratory building are automatically extracted to serve as virtual points. Baselines connecting virtual points and/or target points are extracted and compared with respect to a suitable structural coordinate system. Changes detected from the baseline analysis are compared to a traditional cloud to cloud change analysis demonstrating the potential of the new method for structural analysis.

  3. Image quality metrics for volumetric laser displays

    NASA Astrophysics Data System (ADS)

    Williams, Rodney D.; Donohoo, Daniel

    1991-08-01

    This paper addresses the extensions to the image quality metrics and related human factors research that are needed to establish the baseline standards for emerging volume display technologies. The existing and recently developed technologies for multiplanar volume displays are reviewed with an emphasis on basic human visual issues. Human factors image quality metrics and guidelines are needed to firmly establish this technology in the marketplace. The human visual requirements and the display design tradeoffs for these prototype laser-based volume displays are addressed and several critical image quality issues identified for further research. The American National Standard for Human Factors Engineering of Visual Display Terminal Workstations (ANSIHFS-100) and other international standards (ISO, DIN) can serve as a starting point, but this research base must be extended to provide new image quality metrics for this new technology for volume displays.

  4. Treatment decisions based on scalar and functional baseline covariates.

    PubMed

    Ciarleglio, Adam; Petkova, Eva; Ogden, R Todd; Tarpey, Thaddeus

    2015-12-01

    The amount and complexity of patient-level data being collected in randomized-controlled trials offer both opportunities and challenges for developing personalized rules for assigning treatment for a given disease or ailment. For example, trials examining treatments for major depressive disorder are not only collecting typical baseline data such as age, gender, or scores on various tests, but also data that measure the structure and function of the brain such as images from magnetic resonance imaging (MRI), functional MRI (fMRI), or electroencephalography (EEG). These latter types of data have an inherent structure and may be considered as functional data. We propose an approach that uses baseline covariates, both scalars and functions, to aid in the selection of an optimal treatment. In addition to providing information on which treatment should be selected for a new patient, the estimated regime has the potential to provide insight into the relationship between treatment response and the set of baseline covariates. Our approach can be viewed as an extension of "advantage learning" to include both scalar and functional covariates. We describe our method and how to implement it using existing software. Empirical performance of our method is evaluated with simulated data in a variety of settings and also applied to data arising from a study of patients with major depressive disorder from whom baseline scalar covariates as well as functional data from EEG are available. © 2015, The International Biometric Society.

  5. TNF-α inhibitors do not impair sperm quality in males with ankylosing spondylitis after short-term or long-term treatment.

    PubMed

    Micu, Mihaela C; Micu, Romeo; Surd, Stela; Gîrlovanu, Marinela; Bolboacă, Sorana D; Ostensen, Monika

    2014-07-01

    The aim of this study was to study the influence of active disease status and TNF-α antagonists on sperm quality in a group of AS patients. Twenty-three active AS patients and 42 controls were recruited. Patients' sperm samples were analysed at baseline (previous to) and at 3-6 months after TNF-α therapy (adalimumab, infliximab, etanercept) administration. Baseline assessment was made for only 20 patients, 2 of them proving to have normal fertility, 2 having a pregnant stable partner and the third having a 9-month-old child. Six patients were retested after 12 months of biologic therapy. Each patient acted as his own comparator. Results were further compared with sperm samples from age-matched controls. Sperm analysis was performed according to the World Health Organization (WHO) 1999 guidelines. Patients' baseline assessment showed normozoospermia in 91% and oligozoospermia in 9% of patients. No significant differences in sperm quality were noticed at follow-up visits compared with baseline. Comparison to controls showed no statistically significant differences in semen quality, with some exceptions: the control group presented a higher percentage of non-progressive and immobile sperm cells and higher numbers of head and tail atypias. Sperm quality in patients with active AS and after receiving short- and long-term TNF-α blocker therapy is comparable to sperm quality in healthy controls. Our study confirms that the disease process of AS does not have a major impact on sperm quality and that treatment with anti-TNF has no negative impact on sperm quality even under long-term treatment. © The Author 2014. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  6. The Effect of Personalized Guideline-Concordant Treatment on Quality of Life and Functional Impairment in Bipolar Disorder

    PubMed Central

    Sylvia, Louisa G.; Rabideau, Dustin J.; Nierenberg, Andrew A.; Bowden, Charles L.; Friedman, Edward S.; Iosifescu, Dan V.; Thase, Michael E.; Ketter, Terence; Greiter, Elizabeth A.; Calabrese, Joseph R.; Leon, Andrew C.; Ostacher, Michael J.; Reilly-Harrington, Noreen

    2014-01-01

    Objectives The aims of this study were to evaluate correlates and predictors of life functioning and quality of life in bipolar disorder during a comparative effectiveness trial of moderate doses of lithium. Methods In the Lithium treatment moderate-dose use study (LiTMUS), 283 symptomatic outpatients with bipolar disorder type I or II were randomized to receive lithium plus ”optimal personalized treatment (OPT), or OPT alone. Participants were assessed using structured diagnostic interviews, clinician-rated blinded assessments, and questionnaires. We employ linear mixed effects models to test the effect of treatment overall and adjunct lithium specifically on quality of life or functioning. Similar models are used to examine the association of baseline demographics and clinical features with quality of life and life functioning. Results Quality of life and impaired functioning at baseline were associated with lower income, higher depressive severity, and more psychiatric comorbid conditions. Over six months, patients in both treatment groups improved in quality of life and life functioning (p-values < 0.0001); without a statistically significant difference between the two treatment groups (p-values > 0.05). Within the lithium group, improvement in quality of life and functioning were not associated with concurrent lithium levels at week 12 or week 24 (p-values > 0.05). Lower baseline depressive severity and younger age of onset predicted less improvement in functioning over six months. Conclusions Optimized care for bipolar disorder improves overall quality of life and life functioning, with no additional benefit from adjunct moderate doses of lithium. Illness burden and psychosocial stressors were associated with worse quality of life and lower functioning in individuals with bipolar disorder. PMID:25194782

  7. RECODE: design and baseline results of a cluster randomized trial on cost-effectiveness of integrated COPD management in primary care.

    PubMed

    Kruis, Annemarije L; Boland, Melinde R S; Schoonvelde, Catharina H; Assendelft, Willem J J; Rutten-van Mölken, Maureen P M H; Gussekloo, Jacobijn; Tsiachristas, Apostolos; Chavannes, Niels H

    2013-03-23

    Favorable effects of formal pulmonary rehabilitation in selected moderate to severe COPD patients are well established. Few data are available on the effects and costs of integrated disease management (IDM) programs on quality of care and health status of COPD patients in primary care, representing a much larger group of COPD patients. Therefore, the RECODE trial assesses the long-term clinical and cost-effectiveness of IDM in primary care. RECODE is a cluster randomized trial with two years of follow-up, during which 40 clusters of primary care teams (including 1086 COPD patients) are randomized to IDM or usual care. The intervention started with a 2-day multidisciplinary course in which healthcare providers are trained as a team in essential components of effective COPD IDM in primary care. During the course, the team redesigns the care process and defines responsibilities of different caregivers. They are trained in how to use feedback on process and outcome data to guide implement guideline-driven integrated healthcare. Practice-tailored feedback reports are provided at baseline, and at 6 and 12 months. The team learns the details of an ICT program that supports recording of process and outcome measures. Afterwards, the team designs a time-contingent individual practice plan, agreeing on steps to be taken in order to integrate a COPD IDM program into daily practice. After 6 and 12 months, there is a refresher course for all teams simultaneously to enable them to learn from each other's experience. Health status of patients at 12 months is the primary outcome, measured by the Clinical COPD Questionnaire (CCQ). Secondary outcomes include effects on quality of care, disease-specific and generic health-related quality of life, COPD exacerbations, dyspnea, costs of healthcare utilization, and productivity loss. This article presents the protocol and baseline results of the RECODE trial. This study will allow to evaluate whether IDM implemented in primary care can

  8. 48 CFR 34.202 - Integrated Baseline Reviews.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... inherent risks in offerors'/contractors' performance plans and the underlying management control systems...) The degree to which the management process provides effective and integrated technical/schedule/cost... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Integrated Baseline...

  9. 75 FR 27771 - Overland Trail Transmission, LLC; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-18

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR10-23-000] Overland Trail Transmission, LLC; Notice of Baseline Filing May 11, 2010. Take notice that on May 7, 2010, Overland Trail Transmission, LLC submitted its baseline filing of its Statement of Operating Conditions for transportation...

  10. 75 FR 37786 - Washington 10 Storage Corporation; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-30

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR10-37-000] Washington 10 Storage Corporation; Notice of Baseline Filing June 23, 2010. Take notice that on June 18, 2010, Washington 10 Storage Corporation submitted a baseline filing of its Statement of Operating Conditions for...

  11. 75 FR 35780 - Centana Intrastate Pipeline, LLC; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-23

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR10-35-000] Centana Intrastate Pipeline, LLC; Notice of Baseline Filing June 16, 2010. Take notice that on June 15, 2010, Centana Intrastate Pipeline, LLC submitted a baseline filing of its Storage Statement of Operating Conditions for...

  12. 75 FR 26745 - ONEOK Gas Transportation, LLC; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-12

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR10-18-000] ONEOK Gas Transportation, LLC; Notice of Baseline Filing May 5, 2010. Take notice that on April 28, 2010, ONEOK Gas Transportation, LLC (OGT) submitted its baseline filing of its Statement of Operating Conditions for...

  13. 75 FR 27334 - Regency Intrastate Gas LP; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-14

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR10-20-000] Regency Intrastate Gas LP; Notice of Baseline Filing May 7, 2010. Take notice that on April 30, 2010, Regency Intrastate Gas LP (Regency) submitted its baseline filing of its Statement of Operating Conditions for...

  14. 75 FR 70732 - Enterprise Texas Pipeline LLC; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-18

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR10-92-001] Enterprise Texas Pipeline LLC; Notice of Baseline Filing November 10, 2010. Take notice that on November 9, 2010, Enterprise Texas Pipeline LLC submitted a revised baseline filing of its Statement of Operating Conditions...

  15. 76 FR 7552 - DCP Guadalupe Pipeline, LLC; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-10

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [ Docket No. PR10-31-001] DCP Guadalupe Pipeline, LLC; Notice of Baseline Filing Take notice that on February 3, 2011, DCP Guadalupe Pipeline, LLC submitted a revised baseline filing of their Statement of Operating Conditions for services provided under...

  16. Menopausal quality of life: RCT of yoga, exercise, and omega-3 supplements.

    PubMed

    Reed, Susan D; Guthrie, Katherine A; Newton, Katherine M; Anderson, Garnet L; Booth-LaForce, Cathryn; Caan, Bette; Carpenter, Janet S; Cohen, Lee S; Dunn, Andrea L; Ensrud, Kristine E; Freeman, Ellen W; Hunt, Julie R; Joffe, Hadine; Larson, Joseph C; Learman, Lee A; Rothenberg, Robin; Seguin, Rebecca A; Sherman, Karen J; Sternfeld, Barbara S; LaCroix, Andrea Z

    2014-03-01

    The purpose of this study was to determine the efficacy of 3 nonhormonal therapies for the improvement of menopause-related quality of life in women with vasomotor symptoms. We conducted a 12-week 3 × 2 randomized, controlled, factorial design trial. Peri- and postmenopausal women, 40-62 years old, were assigned randomly to yoga (n = 107), exercise (n = 106), or usual activity (n = 142) and also assigned randomly to a double-blind comparison of omega-3 (n = 177) or placebo (n = 178) capsules. We performed the following interventions: (1) weekly 90-minute yoga classes with daily at-home practice, (2) individualized facility-based aerobic exercise training 3 times/week, and (3) 0.615 g omega-3 supplement, 3 times/day. The outcomes were assessed with the following scores: Menopausal Quality of Life Questionnaire (MENQOL) total and domain (vasomotor symptoms, psychosocial, physical and sexual). Among 355 randomly assigned women who average age was 54.7 years, 338 women (95%) completed 12-week assessments. Mean baseline vasomotor symptoms frequency was 7.6/day, and the mean baseline total MENQOL score was 3.8 (range, 1-8 from better to worse) with no between-group differences. For yoga compared to usual activity, baseline to 12-week improvements were seen for MENQOL total -0.3 (95% confidence interval, -0.6 to 0; P = .02), vasomotor symptom domain (P = .02), and sexuality domain (P = .03) scores. For women who underwent exercise and omega-3 therapy compared with control subjects, improvements in baseline to 12-week total MENQOL scores were not observed. Exercise showed benefit in the MENQOL physical domain score at 12 weeks (P = .02). All women become menopausal, and many of them seek medical advice on ways to improve quality of life; little evidence-based information exists. We found that, among healthy sedentary menopausal women, yoga appears to improve menopausal quality of life; the clinical significance of our finding is uncertain because of the modest effect

  17. Continuing Medical Education Improves Gastroenterologists' Compliance with Inflammatory Bowel Disease Quality Measures.

    PubMed

    Sapir, Tamar; Moreo, Kathleen; Carter, Jeffrey D; Greene, Laurence; Patel, Barry; Higgins, Peter D R

    2016-07-01

    Low rates of compliance with quality measures for inflammatory bowel disease (IBD) have been reported for US gastroenterologists. We assessed the influence of quality improvement (QI) education on compliance with physician quality reporting system (PQRS) measures for IBD and measures related to National Quality Strategy (NQS) priorities. Forty community-based gastroenterologists participated in the QI study; 20 were assigned to educational intervention and control groups, respectively. At baseline, randomly selected charts of patients with moderate-to-severe ulcerative colitis were retrospectively reviewed for the gastroenterologists' performance of 8 PQRS IBD measures and 4 NQS-related measures. The intervention group participated in a series of accredited continuing medical education (CME) activities focusing on QI. Follow-up chart reviews were conducted 6 months after the CME activities. Independent t tests were conducted to compare between-group differences in baseline-to-follow-up rates of documented compliance with each measure. The analysis included 299 baseline charts and 300 follow-up charts. The intervention group had significantly greater magnitudes of improvement than the control group for the following measures: assessment of IBD type, location, and activity (+14 %, p = 0.009); influenza vaccination (+13 %, p = 0.025); pneumococcal vaccination (+20 %, p = 0.003); testing for latent tuberculosis before anti-TNF-α therapy (+10 %, p = 0.028); assessment of hepatitis B virus status before anti-TNF-α therapy (+9 %, p = 0.010); assessment of side effects (+17 %, p = 0.048), and counseling patients about cancer risks (+13 %, p = 0.013). QI-focused CME improves community-based gastroenterologists' compliance with IBD quality measures and measures aligned with NQS priorities.

  18. CASA Uno GPS orbit and baseline experiments

    NASA Technical Reports Server (NTRS)

    Schutz, B. E.; Ho, C. S.; Abusali, P. A. M.; Tapley, B. D.

    1990-01-01

    CASA Uno data from sites distributed in longitude from Australia to Europe have been used to determine orbits of the GPS satellites. The characteristics of the orbits determined from double difference phase have been evaluated through comparisons of two-week solutions with one-week solutions and by comparisons of predicted and estimated orbits. Evidence of unmodeled effects is demonstrated, particularly associated with the orbit planes that experience solar eclipse. The orbit accuracy has been assessed through the repeatability of unconstrained estimated baseline vectors ranging from 245 km to 5400 km. Both the baseline repeatability and the comparison with independent space geodetic methods give results at the level of 1-2 parts in 100,000,000. In addition, the Mojave/Owens Valley (245 km) and Kokee Park/Ft. Davis (5409 km) estimates agree with VLBI and SLR to better than 1 part in 100,000,000.

  19. Precision Measurements of Long-Baseline Neutrino Oscillation at LBNF

    DOE PAGES

    Worcester, Elizabeth

    2015-08-06

    In a long-baseline neutrino oscillation experiment, the primary physics objectives are to determine the neutrino mass hierarchy, to determine the octant of the neutrino mixing angle θ 23, to search for CP violation in neutrino oscillation, and to precisely measure the size of any CP-violating effect that is discovered. This presentation provides a brief introduction to these measurements and reports on efforts to optimize the design of a long-baseline neutrino oscillation experiment, the status of LBNE, and the transition to an international collaboration at LBNF.

  20. Summary of long-baseline systematics session at CETUP*2014

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cherdack, Daniel; Worcester, Elizabeth

    2015-10-15

    A session studying systematics in long-baseline neutrino oscillation physics was held July 14-18, 2014 as part of CETUP* 2014. Systematic effects from flux normalization and modeling, modeling of cross sections and nuclear interactions, and far detector effects were addressed. Experts presented the capabilities of existing and planned tools. A program of study to determine estimates of and requirements for the size of these effects was designed. This document summarizes the results of the CETUP* systematics workshop and the current status of systematic uncertainty studies in long-baseline neutrino oscillation measurements.

  1. Orbiter electrical equipment utilization baseline

    NASA Technical Reports Server (NTRS)

    1980-01-01

    The baseline for utilization of Orbiter electrical equipment in both electrical and Environmental Control and Life Support System (ECLSS) thermal analyses is established. It is a composite catalog of Space Shuttle equipment, as defined in the Shuttle Operational Data Book. The major functions and expected usage of each component type are described. Functional descriptions are designed to provide a fundamental understanding of the Orbiter electrical equipment, to insure correlation of equipment usage within nominal analyses, and to aid analysts in the formulation of off-nominal, contingency analyses.

  2. Baseline factors affecting closure of venous leg ulcers.

    PubMed

    Marston, William A; Ennis, William J; Lantis, John C; Kirsner, Robert S; Galiano, Robert D; Vanscheidt, Wolfgang; Eming, Sabine A; Malka, Marcin; Cargill, D Innes; Dickerson, Jaime E; Slade, Herbert B

    2017-11-01

    The objective of this study was to characterize factors associated with closure of venous leg ulcers (VLUs) in a pooled analysis of subjects from three randomized clinical trials. Closure of VLUs after treatment with HP802-247, an allogeneic living cell therapy consisting of growth-arrested human keratinocytes and fibroblasts, vs standard therapy with compression bandaging was evaluated in three phase 3 clinical trials of similar design. Two trials enrolled subjects with VLUs ranging from 2 cm 2 to 12 cm 2 in area with 12-week treatment periods; the third trial enrolled subjects with VLUs between >12 cm 2 and ≤36 cm 2 with a 16-week treatment period. The first trial went to completion but failed to demonstrate a benefit to therapy with HP802-247 compared with placebo, and because of this, the remaining trials were terminated before completion. On the basis of no differences in outcomes between groups, subjects from both HP802-247 and control groups were pooled across all three studies. Cox proportional hazards regression analysis was employed to evaluate factors associated with VLU closure. This analysis included data from 716 subjects with VLU. Factors evaluated for association with healing included age, gender, race, diabetes, glycated hemoglobin level, body mass index, treatment (HP802-247 vs compression alone), and ulcer characteristics including location and area and duration at baseline. In an initial model including all of these putative factors, the following were significant at the P < .10 level: diagnosis of diabetes mellitus, gender, wound location (ankle or leg), baseline wound area, and wound duration at baseline. In a final model including only these factors, all but diabetes mellitus were significant at the P < .05 level. Effect sizes were as follows (hazard ratio [95% confidence interval]): female gender (1.384 [1.134-1.690]), wound location on the leg (1.490 [1.187-1.871]), smaller wound area at baseline (0.907 [0.887-0.927]), and shorter

  3. Proceedings of a workshop: Multidisciplinary Use of the Very Long Baseline Array

    NASA Technical Reports Server (NTRS)

    1984-01-01

    The National Research Council organized a workshop to gather together experts in very long baseline interometry, astronomy, space navigation, general relativity and the earth sciences. The purpose of the workshop was to provide a forum for consideration of the various possible multi-disciplinary uses of the very long baseline array. Geophysical investigations received major attention. Geodesic uses of the very long baseline array were identified as were uses for fundamental astronomy investigations. Numerous specialized uses were identified.

  4. 75 FR 38802 - DCP Raptor Pipeline, LLC; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-06

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR10-42-000] DCP Raptor Pipeline, LLC; Notice of Baseline Filing June 28, 2010. Take notice that on June 22, 2010, DCP Raptor Pipeline, LLC submitted a baseline filing of its Statement of Operating Conditions for services provided...

  5. 75 FR 27334 - Acacia Natural Gas Corporation; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-14

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR10-16-001] Acacia Natural Gas Corporation; Notice of Baseline Filing May 7, 2010. Take notice that on May 5, 2010, Acacia Natural Gas Corporation (Acacia) submitted a correction to its April 27, 2010, baseline filing of its...

  6. 75 FR 37786 - DCP Guadalupe Pipeline, LLC; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-30

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR10-31-000] DCP Guadalupe Pipeline, LLC; Notice of Baseline Filing June 23, 2010. Take notice that on June 10, 2010, DCP Guadalupe Pipeline, LLC submitted a baseline filing of its Storage Statement of Operating Conditions for services...

  7. Parental quality of life and depressive mood following methylphenidate treatment of children with attention-deficit hyperactivity disorder.

    PubMed

    Kim, Yeni; Kim, Bongseog; Chang, Jae-Seung; Kim, Bung-Nyun; Cho, Soo-Churl; Hwang, Jun-Won

    2014-07-01

    This naturalistic study investigated the associations between quality of life and depressive mood in parents and symptom changes in attention-deficit hyperactivity disorder (ADHD) children. At baseline and at weeks 4 and 8, the parents evaluated their children, who were receiving treatment with osmotic-release oral system methylphenidate (mean dosage 36.3 ± 15.5 mg/day), using the Swanson, Nolan, and Pelham - Fourth Edition (SNAP-IV-18) scale. The parents evaluated themselves using the Beck Depression Inventory (BDI) and the World Health Organization Quality of Life Assessment, Brief Version (WHOQOL-BREF). A significant reduction in SNAP-IV-18 scores and improvements in parental BDI scores and parental WHOQOL-BREF scores were observed. The decrease in BDI scores from baseline to 8 weeks was significantly associated with increases in WHOQOL-BREF sub-domain scores from baseline to 8 weeks, with a greater decrease at 4 weeks and after. The decrease in the SNAP-IV-18 hyperactivity-impulsivity score was significantly associated with increases in WHOQOL social sub-domain scores from baseline to 8 weeks. For those patients who showed a 25% or greater decrease in the SNAP-IV-18 total scores from baseline to 8 weeks, the decreases in the SNAP-IV-18 total score and in the inattention and hyperactivity-impulsivity scores were significantly associated with a decrease in BDI scores from baseline to 8 weeks. Methylphenidate treatment for ADHD was associated with both symptom alleviation in children with ADHD and improvement in parental depressive mood and quality of life, suggesting that the effects of treatment could go beyond symptom improvement in ADHD. © 2014 The Authors. Psychiatry and Clinical Neurosciences © 2014 Japanese Society of Psychiatry and Neurology.

  8. Baseline and Multimodal UAV GCS Interface Design

    DTIC Science & Technology

    2013-07-01

    complete a computerized version of the NASA - TLX assessment of perceived mental workload. 2.3 Results The baseline condition ran smoothly and with...System MALE Medium-altitude, Long-endurance NASA - TLX NASA Task Load Index SA Situation Awareness TDT Tucker Davis Technologies UAV Uninhabited Aerial

  9. THE LONDON LOW EMISSION ZONE BASELINE STUDY

    EPA Science Inventory

    The investigators hope that the LEZ baseline study will present a creative effort to lay the groundwork for studying spatial and temporal changes in air pollutant concentrations and health outcomes in advance of a major regulatory intervention. It is hope that the study wil...

  10. 48 CFR 1034.202 - Integrated Baseline Reviews.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Integrated Baseline... SPECIAL CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 1034.202... plans and the underlying management control systems, and it should formulate a plan to handle these...

  11. 48 CFR 1034.202 - Integrated Baseline Reviews.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Integrated Baseline... SPECIAL CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 1034.202... plans and the underlying management control systems, and it should formulate a plan to handle these...

  12. 48 CFR 1034.202 - Integrated Baseline Reviews.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Integrated Baseline... SPECIAL CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 1034.202... plans and the underlying management control systems, and it should formulate a plan to handle these...

  13. OnabotulinumtoxinA effectiveness on chronic migraine, negative emotional states and sleep quality: a single-center prospective cohort study.

    PubMed

    Aydinlar, Elif Ilgaz; Dikmen, Pinar Yalinay; Kosak, Seda; Kocaman, Ayse Sagduyu

    2017-12-01

    OnabotulinumtoxinA (OnabotA) is considered effective in in patients with chronic migraine (CM) who failed on traditional therapies. This study was designed to evaluate the effect of OnabotA injection series on migraine outcome, negative emotional states and sleep quality in patients with CM. A total of 190 patients with CM (mean (SD) age: 39.3 (10.2) years; 87.9% were female) were included. Data on Pittsburgh sleep quality index (PSQI), headache frequency and severity, number of analgesics used, Migraine Disability Assessment Scale. (MIDAS) scores and Depression, Anxiety and Stress Scale (DASS-21) were evaluated at baseline (visit 1) and 4 consecutive follow up visits, each conducted after OnabotA injection series; at week 12 (visit 2), week 24 (visit 3), week 36 (visit 4) and week 48 (visit 5) to evaluate change from baseline to follow up. From baseline to visit 5, significant decrease was noted in least square (LS) mean headache frequency (from 19.5 to 8.4, p = 0.002), headache severity (from 8.1 to 6.1, p = 0.017), number of analgesics (from 26.9 to 10.4, p = 0.023) and MIDAS scores (from 67.3 to 18.5, p < 0.001). No significant change from baseline was noted in global PSOI and DASS-21 scores throughout the study. Our findings revealed that OnabotA therapy was associated with significant improvement in migraine outcome leading to decrease in headache frequency and severity, number of analgesics used and MIDAS scores. While no significant change was noted in overall sleep quality and prevalence of negative emotional states, patients without negative emotional states at baseline showed improved sleep quality throughout the study.

  14. Assessment of indoor environmental quality in existing multi-family buildings in North-East Europe.

    PubMed

    Du, Liuliu; Prasauskas, Tadas; Leivo, Virpi; Turunen, Mari; Pekkonen, Maria; Kiviste, Mihkel; Aaltonen, Anu; Martuzevicius, Dainius; Haverinen-Shaughnessy, Ulla

    2015-06-01

    Sixteen existing multi-family buildings (94 apartments) in Finland and 20 (96 apartments) in Lithuania were investigated prior to their renovation in order to develop and test out a common protocol for the indoor environmental quality (IEQ) assessment, and to assess the potential for improving IEQ along with energy efficiency. Baseline data on buildings, as well as data on temperature (T), relative humidity (RH), carbon dioxide (CO2), carbon monoxide (CO), particulate matter (PM), nitrogen dioxide (NO2), formaldehyde, volatile organic compounds (VOCs), radon, and microbial content in settled dust were collected from each apartment. In addition, questionnaire data regarding housing quality and health were collected from the occupants. The results indicated that most measured IEQ parameters were within recommended limits. However, different baselines in each country were observed especially for parameters related to thermal conditions and ventilation. Different baselines were also observed for the respondents' satisfaction with their residence and indoor air quality, as well as their behavior related to indoor environment. In this paper, we present some evidence for the potential in improving IEQ along with energy efficiency in the current building stock, followed by discussion of possible IEQ indicators and development of the assessment protocol. Copyright © 2015 Elsevier Ltd. All rights reserved.

  15. Single-site Baseline and Short-term Outcomes of Clinical Characteristics and Life Quality Evaluation of Chinese Wet Age-related Macular Degeneration Patients in Routine Clinical Practice

    PubMed Central

    Wang, Li-Li; Liu, Wen-Jia; Liu, Hai-Yun; Xu, Xun

    2015-01-01

    Background: Age-related macular degeneration (AMD) is the leading cause of irreversible vision loss among the older population. In China, treatment of age-related ocular diseases is becoming a priority in eye care services. This study was to investigate the clinical characteristics and quality of life of Chinese patients with wet AMD and current treatment types, to evaluate short-term gains in different treatments, and to investigate associations between visual function and vision-related quality of life (VRQoL). Methods: A prospective, observational, noninterventional study was conducted. Basic data were collected from patients with clinical diagnoses of wet AMD before clinical assessments at baseline. VRQoL was measured with the Chinese version of the National Eye Institute Visual Function Questionnaire-25 (NEI VFQ-25). Correlations of the NEI VFQ-25 subscale scores with best-corrected visual acuity (BCVA) and between-group differences were analyzed. Results: A total of 80 wet AMD patients were enrolled, with the mean age of 68.40 years. About one-quarter of wet AMD patients received intravitreal (IVT) ranibizumab treatment, and 67% of them were treated on a pro re nata basis. The visual acuity of patients treated with IVT ranibizumab at month 3 after treatment was significantly increased, whereas patients treated with traditional Chinese medicine achieved no significant improvement. Cronbach's α for the NEI VFQ-25 subscales ranged from 0.697 to 0.843. Eight subscale and overall composite scores were moderately correlated with the BCVA of the better-seeing eye. Significant differences in the overall NEI VFQ-25 scores and other subscales were observed between patients with BCVA in the better-seeing eye of less than 50 letters and the others. Conclusions: Patients treated with IVT ranibizumab experienced better vision improvement at short-term follow-up. The Chinese version of the NEI VFQ-25 is a valid and reliable tool for assessing the VRQoL of Chinese wet AMD

  16. Importance of the pre-industrial baseline for likelihood of exceeding Paris goals

    NASA Astrophysics Data System (ADS)

    Schurer, Andrew P.; Mann, Michael E.; Hawkins, Ed; Tett, Simon F. B.; Hegerl, Gabriele C.

    2017-08-01

    During the Paris conference in 2015, nations of the world strengthened the United Nations Framework Convention on Climate Change by agreeing to holding `the increase in the global average temperature to well below 2 °C above pre-industrial levels and pursuing efforts to limit the temperature increase to 1.5 °C' (ref. ). However, `pre-industrial' was not defined. Here we investigate the implications of different choices of the pre-industrial baseline on the likelihood of exceeding these two temperature thresholds. We find that for the strongest mitigation scenario RCP2.6 and a medium scenario RCP4.5, the probability of exceeding the thresholds and timing of exceedance is highly dependent on the pre-industrial baseline; for example, the probability of crossing 1.5 °C by the end of the century under RCP2.6 varies from 61% to 88% depending on how the baseline is defined. In contrast, in the scenario with no mitigation, RCP8.5, both thresholds will almost certainly be exceeded by the middle of the century with the definition of the pre-industrial baseline of less importance. Allowable carbon emissions for threshold stabilization are similarly highly dependent on the pre-industrial baseline. For stabilization at 2 °C, allowable emissions decrease by as much as 40% when earlier than nineteenth-century climates are considered as a baseline.

  17. 76 FR 47569 - Arcadia Gas Storage, LLC; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-05

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket Nos. PR11-111-000; PR11-111-001] Arcadia Gas Storage, LLC; Notice of Baseline Filing Take notice that on May 19, 2011 and July 26, 2011, Arcadia Gas Storage, LLC submitted a revised baseline filing of their Statement of Operating Conditions...

  18. A Simple Method to Control Positive Baseline Trend within Data Nonoverlap

    ERIC Educational Resources Information Center

    Parker, Richard I.; Vannest, Kimberly J.; Davis, John L.

    2014-01-01

    Nonoverlap is widely used as a statistical summary of data; however, these analyses rarely correct unwanted positive baseline trend. This article presents and validates the graph rotation for overlap and trend (GROT) technique, a hand calculation method for controlling positive baseline trend within an analysis of data nonoverlap. GROT is…

  19. 75 FR 33799 - Moss Bluff Hub, LLC; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-15

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR10-28-000] Moss Bluff Hub, LLC; Notice of Baseline Filing June 8, 2010. Take notice that on June 1, 2010, Moss Bluff Hub, LLC submitted a baseline filing of its Statement of General Terms and Standard Operations Conditions for storage...

  20. Baseline glucocorticoids are drivers of body mass gain in a diving seabird

    USGS Publications Warehouse

    Hennin, Holly; Berlin, Alicia; Love, Oliver P.

    2016-01-01

    Life-history trade-offs are influenced by variation in individual state, with individuals in better condition often completing life-history stages with greater success. Although resource accrual significantly impacts key life-history decisions such as the timing of reproduction, little is known about the underlying mechanisms driving resource accumulation. Baseline corticosterone (CORT, the primary avian glucocorticoid) mediates daily and seasonal energetics, responds to changes in food availability, and has been linked to foraging behavior, making it a strong potential driver of individual variation in resource accrual and deposition. Working with a captive colony of white-winged scoters (Melanitta fusca deglandi), we aimed to causally determine whether variation in baseline CORT drives individual body mass gains mediated through fattening rate (plasma triglycerides corrected for body mass). We implanted individuals with each of three treatment pellets to elevate CORT within a baseline range in a randomized order: control, low dose of CORT, high dose of CORT, then blood sampled and recorded body mass over a two-week period to track changes in baseline CORT, body mass, and fattening rates. The high CORT treatment significantly elevated levels of plasma hormone for a short period of time within the biologically relevant, baseline range for this species, but importantly did not inhibit the function of the HPA (hypothalamic–pituitary–adrenal) axis. Furthermore, an elevation in baseline CORT resulted in a consistent increase in body mass throughout the trial period compared to controls. This is some of the first empirical evidence demonstrating that elevations of baseline CORT within a biologically relevant range have a causal, direct, and positive influence on changes in body mass.

  1. Baseline glucocorticoids are drivers of body mass gain in a diving seabird.

    PubMed

    Hennin, Holly L; Wells-Berlin, Alicia M; Love, Oliver P

    2016-03-01

    Life-history trade-offs are influenced by variation in individual state, with individuals in better condition often completing life-history stages with greater success. Although resource accrual significantly impacts key life-history decisions such as the timing of reproduction, little is known about the underlying mechanisms driving resource accumulation. Baseline corticosterone (CORT, the primary avian glucocorticoid) mediates daily and seasonal energetics, responds to changes in food availability, and has been linked to foraging behavior, making it a strong potential driver of individual variation in resource accrual and deposition. Working with a captive colony of white-winged scoters (Melanitta fusca deglandi), we aimed to causally determine whether variation in baseline CORT drives individual body mass gains mediated through fattening rate (plasma triglycerides corrected for body mass). We implanted individuals with each of three treatment pellets to elevate CORT within a baseline range in a randomized order: control, low dose of CORT, high dose of CORT, then blood sampled and recorded body mass over a two-week period to track changes in baseline CORT, body mass, and fattening rates. The high CORT treatment significantly elevated levels of plasma hormone for a short period of time within the biologically relevant, baseline range for this species, but importantly did not inhibit the function of the HPA (hypothalamic-pituitary-adrenal) axis. Furthermore, an elevation in baseline CORT resulted in a consistent increase in body mass throughout the trial period compared to controls. This is some of the first empirical evidence demonstrating that elevations of baseline CORT within a biologically relevant range have a causal, direct, and positive influence on changes in body mass.

  2. The Cross-Sectional Association between Diet Quality and Depressive Symptomology amongst Fijian Adolescents

    PubMed Central

    Sinclair, Rachael; Millar, Lynne; Allender, Steven; Snowdon, Wendy; Waqa, Gade; Jacka, Felice; Moodie, Marj; Petersen, Solveig; Swinburn, Boyd

    2016-01-01

    Objective To examine the relationship between diet quality and depressive symptomology amongst a community-based sample of Fijian adolescents. Methods Participants included 7,237 adolescents (52.6% girls; mean age 15.6 years) at baseline (2005) and 2,948 (56% girls; mean age 17.4 years) at follow-up (2007/2008), from the Pacific Obesity Prevention in Communities Project. Intervention schools (n = 7) were selected from Nasinu, near Suva on the main Fijian island Viti Levu, and comparison schools (n = 11) were chosen from towns on the opposite, west side of the island. A dietary questionnaire was used to measure diet quality. Factor analysis clustered dietary variables into two unique and independent factors, referred to as healthy diet quality and unhealthy diet quality. Depressive symptomology was assessed via the emotional subscale of the Paediatric Quality of Life Inventory. Both measures were self-reported and self-administered. Multiple linear regression was used to test cross-sectional associations (at baseline and follow-up) between diet quality and depressive symptomology. Variables controlled for included gender, age, ethnicity, study condition, BMI-z scores, and physical activity. Findings Strong, positive dose-response associations between healthy diet and high emotional scores (lower depressive symptomology) were found in cross-sectional analyses at baseline and follow-up, among boys and girls. No association was found between emotional health and unhealthy diet. Conclusions This study suggests that cross-sectional relationships exist between a high quality diet during adolescence and less depressive symptoms, however more evidence is required to determine if these two variables are linked causally. Trial population health strategies that use dietary interventions as a mechanism for mental health promotion provide an opportunity to further test these associations. If this is indeed a true relationship, these forms of interventions have the potential to

  3. Impact of waiting time on the quality of life of patients awaiting coronary artery bypass grafting.

    PubMed

    Sampalis, J; Boukas, S; Liberman, M; Reid, T; Dupuis, G

    2001-08-21

    A lack of resources has created waiting lists for many elective surgical procedures within Canada's universal health care system. Coronary artery bypass grafting (CABG) for the treatment of atherosclerotic ischemic heart disease is one of these affected surgical procedures. We studied the impact of waiting times on the quality of life of patients awaiting CABG. A prospective cohort of 266 patients from 3 hospitals in Montreal was used. Patients who gave informed consent were followed from the time they were registered for CABG until 6 months after surgery; recruitment began in November 1993, and the last follow-up was completed in July 1995. Patient groups were classified according to the duration of the wait for CABG (< or = 97 days or > 97 days). We measured the following outcomes: quality of life (using the Medical Outcomes Study 36-item Short Form [SF-36]), incidence of chest pain (using the New York Heart Association angina classification), frequency of symptoms (using the Cardiac Symptom Inventory) and rates of complications and death before and after surgery. There were no differences in quality of life at baseline between the 2 groups. Immediately before surgery, compared with patients who waited 97 days or less, those who waited longer had significantly reduced physical functioning (change from baseline SF-36 score 0 v. -4 respectively, p = 0.001), vitality (change from baseline score -0.1 v. -1.3, p = 0.01), social functioning (change from baseline score 0.4 v. -0.4, p = 0.03) and general health (change from baseline score 1.1 v. -1.7, p = 0.001). At 6 months after surgery, compared with patients who waited 97 days or less for CABG, those who waited longer had reduced physical functioning (change from baseline SF-36 score 4.0 v. -0.1 respectively, p = 0.001), physical role (change from baseline score 0.8 v. 0.0, p = 0.001), vitality (change from baseline score 2.2 v. 0.9, p = 0.001), mental health (change from baseline score 1.2 v. 0.0, p = 0.001) and

  4. A nonpharmacological approach to improve sleep quality in older adults.

    PubMed

    Rawtaer, Iris; Mahendran, Rathi; Chan, Hui Yu; Lei, Feng; Kua, Ee Heok

    2018-06-01

    Poor sleep quality is highly prevalent among older adults and is associated with poor quality of life, cognitive and physical decline, depression, and increased mortality. Medication options commonly used are not ideal, and alternative treatment strategies are needed. We evaluate a community-based psychosocial intervention program and its effect on sleep quality in older adults. Elderly participants aged 60 and above were included. Those with Geriatric Depression Scale and Geriatric Anxiety Inventory scores above 5 and 10, respectively, were excluded. The community program included tai chi exercise, art therapy, mindfulness awareness practice, and music reminiscence therapy. Pittsburgh Sleep Quality Index, Geriatric Depression Scale, and Geriatric Anxiety Inventory were administered at baseline and at 1 year. A hundred and eighty-nine subjects (44 men, 145 women; mean age = 69 years, SD = 5.7, range = 60-89) participated. The proportion of participants with good sleep quality had increased from 58.2% to 64.6%. Sleep disturbance was significantly reduced (baseline, 1.04; postintervention, 0.76; mean difference 0.28; P < .01); men experienced greater improvement (P < .001). Improvements were independent of changes in depressive and anxiety symptoms. Participation in this community program led to positive effects on sleep disturbances after a year. Psychosocial interventions have potential as a nondrug intervention approach for sleep problems, and further research is needed to understand its mediating mechanisms. © 2017 John Wiley & Sons Australia, Ltd.

  5. Information Technology Sector Baseline Risk Assessment

    DTIC Science & Technology

    2009-08-01

    alternative root be economically advantageous , an actor’s ability to exploit market forces and create an alternative root would be significantly improved...conduct their operations. Therefore, a loss or disruption to Internet services would not be advantageous for the desired outcomes of these syndicates.26... eCommerce Service loss or disruption [C] Traffic Redirection [C] = Undesired consequence Information Technology Sector Baseline Risk Assessment

  6. Questa Baseline and Pre-Mining Ground-Water Quality Investigation. 25. Summary of Results and Baseline and Pre-Mining Ground-Water Geochemistry, Red River Valley, Taos County, New Mexico, 2001-2005

    USGS Publications Warehouse

    Nordstrom, D. Kirk

    2008-01-01

    Active and inactive mine sites are challenging to remediate because of their complexity and scale. Regulations meant to achieve environmental restoration at mine sites are equally challenging to apply for the same reasons. The goal of environmental restoration should be to restore contaminated mine sites, as closely as possible, to pre-mining conditions. Metalliferous mine sites in the Western United States are commonly located in hydrothermally altered and mineralized terrain in which pre-mining concentrations of metals were already anomalously high. Typically, those pre-mining concentrations were not measured, but sometimes they can be reconstructed using scientific inference. Molycorp?s Questa molybdenum mine in the Red River Valley, northern New Mexico, is located near the margin of the Questa caldera in a highly mineralized region. The State of New Mexico requires that ground-water quality standards be met on closure unless it can be shown that potential contaminant concentrations were higher than the standards before mining. No ground water at the mine site had been chemically analyzed before mining. The aim of this investigation, in cooperation with the New Mexico Environment Department (NMED), is to infer the pre-mining ground-water quality by an examination of the geologic, hydrologic, and geochemical controls on ground-water quality in a nearby, or proximal, analog site in the Straight Creek drainage basin. Twenty-seven reports contain details of investigations on the geological, hydrological, and geochemical characteristics of the Red River Valley that are summarized in this report. These studies include mapping of surface mineralogy by Airborne Visible-Infrared Imaging Spectrometry (AVIRIS); compilations of historical surface- and ground- water quality data; synoptic/tracer studies with mass loading and temporal water-quality trends of the Red River; reaction-transport modeling of the Red River; environmental geology of the Red River Valley; lake

  7. Development Of Regional Climate Mitigation Baseline For A DominantAgro-Ecological Zone Of Karnataka, India

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sudha, P.; Shubhashree, D.; Khan, H.

    2007-06-01

    Setting a baseline for carbon stock changes in forest andland use sector mitigation projects is an essential step for assessingadditionality of the project. There are two approaches for settingbaselines namely, project-specific and regional baseline. This paperpresents the methodology adopted for estimating the land available formitigation, for developing a regional baseline, transaction cost involvedand a comparison of project-specific and regional baseline. The studyshowed that it is possible to estimate the potential land and itssuitability for afforestation and reforestation mitigation projects,using existing maps and data, in the dry zone of Karnataka, southernIndia. The study adopted a three-step approach for developing a regionalbaseline,more » namely: i) identification of likely baseline options for landuse, ii) estimation of baseline rates of land-use change, and iii)quantification of baseline carbon profile over time. The analysis showedthat carbon stock estimates made for wastelands and fallow lands forproject-specific as well as the regional baseline are comparable. Theratio of wasteland Carbon stocks of a project to regional baseline is1.02, and that of fallow lands in the project to regional baseline is0.97. The cost of conducting field studies for determination of regionalbaseline is about a quarter of the cost of developing a project-specificbaseline on a per hectare basis. The study has shown the reliability,feasibility and cost-effectiveness of adopting regional baseline forforestry sectormitigation projects.« less

  8. The prognostic utility of baseline alpha-fetoprotein for hepatocellular carcinoma patients.

    PubMed

    Silva, Jack P; Gorman, Richard A; Berger, Nicholas G; Tsai, Susan; Christians, Kathleen K; Clarke, Callisia N; Mogal, Harveshp; Gamblin, T Clark

    2017-12-01

    Alpha-fetoprotein (AFP) has a valuable role in postoperative surveillance for hepatocellular carcinoma (HCC) recurrence. The utility of pretreatment or baseline AFP remains controversial. The present study hypothesized that elevated baseline AFP levels are associated with worse overall survival in HCC patients. Adult HCC patients were identified using the National Cancer Database (2004-2013). Patients were stratified according to baseline AFP measurements into the following groups: Negative (<20), Borderline (20-199), Elevated (200-1999), and Highly Elevated (>2000). The primary outcome was overall survival (OS), which was analyzed by log-rank test and graphed using Kaplan-Meier method. Multivariate regression modeling was used to determine hazard ratios (HR) for OS. Of 41 107 patients identified, 15 809 (33.6%) were Negative. Median overall survival was highest in the Negative group, followed by Borderline, Elevated, and Highly Elevated (28.7 vs 18.9 vs 8.8 vs 3.2 months; P < 0.001). On multivariate analysis, overall survival hazard ratios for the Borderline, Elevated, and Highly Elevated groups were 1.18 (P = 0.267), 1.94 (P < 0.001), and 1.77 (P = 0.007), respectively (reference Negative). Baseline AFP independently predicted overall survival in HCC patients regardless of treatment plan. A baseline AFP value is a simple and effective method to assist in expected survival for HCC patients. © 2017 Wiley Periodicals, Inc.

  9. Mercury exposure may suppress baseline corticosterone levels in juvenile birds.

    PubMed

    Herring, Garth; Ackerman, Joshua T; Herzog, Mark P

    2012-06-05

    Mercury exposure has been associated with a wide variety of negative reproductive responses in birds, however few studies have examined the potential for chick impairment via the hypothalamic-pituitary-adrenal (HPA) axis. The HPA axis regulates corticosterone levels during periods of stress. We examined the relationship between baseline fecal corticosterone metabolite concentrations and mercury concentrations in down feathers of recently hatched (<3 days) and blood of older (15-37 days) Forster's tern (Sterna forsteri) chicks in San Francisco Bay, California. Baseline fecal corticosterone metabolite concentrations were negatively correlated with mercury concentrations in blood of older chicks (decreasing by 81% across the range of observed mercury concentrations) while accounting for positive correlations between corticosterone concentrations and number of fledgling chicks within the colony and chick age. In recently hatched chicks, baseline fecal corticosterone metabolite concentrations were weakly negatively correlated with mercury concentrations in down feathers (decreasing by 45% across the range of observed mercury concentrations) while accounting for stronger positive correlations between corticosterone concentrations and colony nest abundance and date. These results indicate that chronic mercury exposure may suppress baseline corticosterone concentrations in tern chicks and suggests that a juvenile bird's ability to respond to stress may be reduced via the downregulation of the HPA axis.

  10. Effect of computer game playing on baseline laparoscopic simulator skills.

    PubMed

    Halvorsen, Fredrik H; Cvancarova, Milada; Fosse, Erik; Mjåland, Odd

    2013-08-01

    Studies examining the possible association between computer game playing and laparoscopic performance in general have yielded conflicting results and neither has a relationship between computer game playing and baseline performance on laparoscopic simulators been established. The aim of this study was to examine the possible association between previous and present computer game playing and baseline performance on a virtual reality laparoscopic performance in a sample of potential future medical students. The participating students completed a questionnaire covering the weekly amount and type of computer game playing activity during the previous year and 3 years ago. They then performed 2 repetitions of 2 tasks ("gallbladder dissection" and "traverse tube") on a virtual reality laparoscopic simulator. Performance on the simulator were then analyzed for association to their computer game experience. Local high school, Norway. Forty-eight students from 2 high school classes volunteered to participate in the study. No association between prior and present computer game playing and baseline performance was found. The results were similar both for prior and present action game playing and prior and present computer game playing in general. Our results indicate that prior and present computer game playing may not affect baseline performance in a virtual reality simulator.

  11. The Fermilab Short-Baseline Program: MicroBooNE

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schukraft, Anne

    2016-01-01

    The MicroBooNE experiment is the first of three detectors of the Fermilab short-baseline neutrino program that started operation in the Booster Neutrino Beamline in October 2015 [1]. When completed, the three-detector lineup will explore short-baseline neutrino oscillations and will be sensitive to sterile neutrino scenarios. MicroBooNE in itself is now starting its own physics program, with the measurement of neutrino-argon cross sections in the ~1GeV range being one of its main physics goals. These proceedings describe the status of the detector, the start of operation, and the automated reconstruction of the first neutrino events observed with MicroBooNE. Prospects for upcomingmore » cross section measurements are also given.« less

  12. U-10Mo Baseline Fuel Fabrication Process Description

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hubbard, Lance R.; Arendt, Christina L.; Dye, Daniel F.

    This document provides a description of the U.S. High Power Research Reactor (USHPRR) low-enriched uranium (LEU) fuel fabrication process. This document is intended to be used in conjunction with the baseline process flow diagram (PFD) presented in Appendix A. The baseline PFD is used to document the fabrication process, communicate gaps in technology or manufacturing capabilities, convey alternatives under consideration, and as the basis for a dynamic simulation model of the fabrication process. The simulation model allows for the assessment of production rates, costs, and manufacturing requirements (manpower, fabrication space, numbers and types of equipment, etc.) throughout the lifecycle ofmore » the USHPRR program. This document, along with the accompanying PFD, is updated regularly« less

  13. Integrated Baseline Review (IBR) Handbook

    NASA Technical Reports Server (NTRS)

    Fleming, Jon F.; Terrell, Stefanie M.

    2018-01-01

    The purpose of this handbook is intended to be a how-to guide to prepare for, conduct, and close-out an Integrated Baseline Review (IBR). It discusses the steps that should be considered, describes roles and responsibilities, tips for tailoring the IBR based on risk, cost, and need for management insight, and provides lessons learned from past IBRs. Appendices contain example documentation typically used in connection with an IBR. Note that these appendices are examples only, and should be tailored to meet the needs of individual projects and contracts.

  14. Predicting Baseline for Analysis of Electricity Pricing

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kim, T.; Lee, D.; Choi, J.

    2016-05-03

    To understand the impact of new pricing structure on residential electricity demands, we need a baseline model that captures every factor other than the new price. The standard baseline is a randomized control group, however, a good control group is hard to design. This motivates us to devlop data-driven approaches. We explored many techniques and designed a strategy, named LTAP, that could predict the hourly usage years ahead. The key challenge in this process is that the daily cycle of electricity demand peaks a few hours after the temperature reaching its peak. Existing methods rely on the lagged variables ofmore » recent past usages to enforce this daily cycle. These methods have trouble making predictions years ahead. LTAP avoids this trouble by assuming the daily usage profile is determined by temperature and other factors. In a comparison against a well-designed control group, LTAP is found to produce accurate predictions.« less

  15. Benefits of massage-myofascial release therapy on pain, anxiety, quality of sleep, depression, and quality of life in patients with fibromyalgia.

    PubMed

    Castro-Sánchez, Adelaida María; Matarán-Peñarrocha, Guillermo A; Granero-Molina, José; Aguilera-Manrique, Gabriel; Quesada-Rubio, José Manuel; Moreno-Lorenzo, Carmen

    2011-01-01

    Fibromyalgia is a chronic syndrome characterized by generalized pain, joint rigidity, intense fatigue, sleep alterations, headache, spastic colon, craniomandibular dysfunction, anxiety, and depression. The purpose of the present study was to determine whether massage-myofascial release therapy can improve pain, anxiety, quality of sleep, depression, and quality of life in patients with fibromyalgia. A randomized controlled clinical trial was performed. Seventy-four fibromyalgia patients were randomly assigned to experimental (massage-myofascial release therapy) and placebo (sham treatment with disconnected magnotherapy device) groups. The intervention period was 20 weeks. Pain, anxiety, quality of sleep, depression, and quality of life were determined at baseline, after the last treatment session, and at 1 month and 6 months. Immediately after treatment and at 1 month, anxiety levels, quality of sleep, pain, and quality of life were improved in the experimental group over the placebo group. However, at 6 months postintervention, there were only significant differences in the quality of sleep index. Myofascial release techniques improved pain and quality of life in patients with fibromyalgia.

  16. Benefits of Massage-Myofascial Release Therapy on Pain, Anxiety, Quality of Sleep, Depression, and Quality of Life in Patients with Fibromyalgia

    PubMed Central

    Castro-Sánchez, Adelaida María; Matarán-Peñarrocha, Guillermo A.; Granero-Molina, José; Aguilera-Manrique, Gabriel; Quesada-Rubio, José Manuel; Moreno-Lorenzo, Carmen

    2011-01-01

    Fibromyalgia is a chronic syndrome characterized by generalized pain, joint rigidity, intense fatigue, sleep alterations, headache, spastic colon, craniomandibular dysfunction, anxiety, and depression. The purpose of the present study was to determine whether massage-myofascial release therapy can improve pain, anxiety, quality of sleep, depression, and quality of life in patients with fibromyalgia. A randomized controlled clinical trial was performed. Seventy-four fibromyalgia patients were randomly assigned to experimental (massage-myofascial release therapy) and placebo (sham treatment with disconnected magnotherapy device) groups. The intervention period was 20 weeks. Pain, anxiety, quality of sleep, depression, and quality of life were determined at baseline, after the last treatment session, and at 1 month and 6 months. Immediately after treatment and at 1 month, anxiety levels, quality of sleep, pain, and quality of life were improved in the experimental group over the placebo group. However, at 6 months postintervention, there were only significant differences in the quality of sleep index. Myofascial release techniques improved pain and quality of life in patients with fibromyalgia. PMID:21234327

  17. Environmental Quality and the U.S. Power Sector: Air Quality, Land Use and Environmental Justice

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Massetti, Emanuele; Brown, Marilyn Ann; Lapsa, Melissa Voss

    This baseline report summarizes key environmental quality issues associated with electricity generation, transmission, distribution, and end use in the United States. Its scope includes non-greenhouse gas air pollution (i.e., sulfur dioxide, nitrogen oxides, particulate matter and hazardous air pollutants), land use, water pollution, ecological impacts, human health, and environmental justice. The discussion characterizes both current impacts and recent trends, as well as assessments of key drivers of change. For example, the air emissions section includes a quantitative decomposition analysis of the drivers of change in sulfur dioxide emissions reductions from coal-fired power plants. The report is divided into four topicalmore » sections: air emissions, land use and ecology, water quality, and environmental justice.« less

  18. Determinants of Health and the Quality of Life in the Bella Coola Valley

    ERIC Educational Resources Information Center

    Michalos, Alex C.; Thommasen, Harvey V.; Read, Rua; Anderson, Nancy; Zumbo, Bruno D.

    2005-01-01

    The aim of this investigation is to obtain some baseline self-reported data of the health status and overall quality of life of all residents of the Bella Coola Valley of British Columbia aged 17 years or older, and to measure the impact of a set of designated health determinants on their health and quality of life. In the period from August to…

  19. Differing predictive relationships between baseline LDL-C, systolic blood pressure, and cardiovascular outcomes.

    PubMed

    Deedwania, Prakash C; Pedersen, Terje R; DeMicco, David A; Breazna, Andrei; Betteridge, D John; Hitman, Graham A; Durrington, Paul; Neil, Andrew

    2016-11-01

    Traditional cardiovascular risk factors, such as hypertension and dyslipidemia, predispose individuals to cardiovascular disease, particularly patients with diabetes. We investigated the predictive value of baseline systolic blood pressure (SBP) and low-density lipoprotein cholesterol (LDL-C) on the risk of vascular outcomes in a large population of patients at high risk of future cardiovascular events. Data were pooled from the TNT (Treating to New Targets), CARDS (Collaborative Atorvastatin Diabetes Study), and IDEAL (Incremental Decrease in End-Points Through Aggressive Lipid Lowering) trials and included a total of 21,727 patients (TNT: 10,001; CARDS: 2838; IDEAL: 8888). The effect of baseline SBP and LDL-C on cardiovascular events, coronary events, and stroke was evaluated using a multivariate Cox proportional-hazards model. Overall, risk of cardiovascular events was significantly higher for patients with higher baseline SBP or LDL-C. Higher baseline SBP was significantly predictive of stroke but not coronary events. Conversely, higher baseline LDL-C was significantly predictive of coronary events but not stroke. Results from the subgroup with diabetes (5408 patients; TNT: 1501; CARDS: 2838; IDEAL: 1069) were broadly consistent with those of the total cohort: baseline SBP and LDL-C were significantly predictive of cardiovascular events overall, with the association to LDL-C predominantly related to an effect on coronary events. However, baseline SBP was not predictive of either coronary or stroke events in the pooled diabetic population. In this cohort of high-risk patients, baseline SBP and LDL-C were significantly predictive of cardiovascular outcomes, but this effect may differ between the cerebrovascular and coronary systems. NCT00327691 (TNT); NCT00327418 (CARDS); NCT00159835 (IDEAL). Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  20. Analysis of Seasonal Signal in GPS Short-Baseline Time Series

    NASA Astrophysics Data System (ADS)

    Wang, Kaihua; Jiang, Weiping; Chen, Hua; An, Xiangdong; Zhou, Xiaohui; Yuan, Peng; Chen, Qusen

    2018-04-01

    Proper modeling of seasonal signals and their quantitative analysis are of interest in geoscience applications, which are based on position time series of permanent GPS stations. Seasonal signals in GPS short-baseline (< 2 km) time series, if they exist, are mainly related to site-specific effects, such as thermal expansion of the monument (TEM). However, only part of the seasonal signal can be explained by known factors due to the limited data span, the GPS processing strategy and/or the adoption of an imperfect TEM model. In this paper, to better understand the seasonal signal in GPS short-baseline time series, we adopted and processed six different short-baselines with data span that varies from 2 to 14 years and baseline length that varies from 6 to 1100 m. To avoid seasonal signals that are overwhelmed by noise, each of the station pairs is chosen with significant differences in their height (> 5 m) or type of the monument. For comparison, we also processed an approximately zero baseline with a distance of < 1 m and identical monuments. The daily solutions show that there are apparent annual signals with annual amplitude of 1 mm (maximum amplitude of 1.86 ± 0.17 mm) on almost all of the components, which are consistent with the results from previous studies. Semi-annual signal with a maximum amplitude of 0.97 ± 0.25 mm is also present. The analysis of time-correlated noise indicates that instead of flicker (FL) or random walk (RW) noise, band-pass-filtered (BP) noise is valid for approximately 40% of the baseline components, and another 20% of the components can be best modeled by a combination of the first-order Gauss-Markov (FOGM) process plus white noise (WN). The TEM displacements are then modeled by considering the monument height of the building structure beneath the GPS antenna. The median contributions of TEM to the annual amplitude in the vertical direction are 84% and 46% with and without additional parts of the monument, respectively. Obvious

  1. On Internal Validity in Multiple Baseline Designs

    ERIC Educational Resources Information Center

    Pustejovsky, James E.

    2014-01-01

    Single-case designs are a class of research designs for evaluating intervention effects on individual cases. The designs are widely applied in certain fields, including special education, school psychology, clinical psychology, social work, and applied behavior analysis. The multiple baseline design (MBD) is the most frequently used single-case…

  2. Toward Baseline Software Anomalies in NASA Missions

    NASA Technical Reports Server (NTRS)

    Layman, Lucas; Zelkowitz, Marvin; Basili, Victor; Nikora, Allen P.

    2012-01-01

    In this fast abstract, we provide preliminary findings an analysis of 14,500 spacecraft anomalies from unmanned NASA missions. We provide some baselines for the distributions of software vs. non-software anomalies in spaceflight systems, the risk ratings of software anomalies, and the corrective actions associated with software anomalies.

  3. Quality of life of head and neck cancer patients in urban and regional areas: An Australian perspective.

    PubMed

    Pateman, Kelsey A; Cockburn, Nicole L; Batstone, Martin D; Ford, Pauline J

    2018-06-01

    Head and neck cancer treatment affects quality of life. There are differences in quality of life outcomes and perceived supportive care needs between cancer patients living in metropolitan and regional-remote areas. This study investigated quality of life over the first 6 months following head and neck cancer diagnosis and observed differences in quality of life by geographical location. Prospective observational study. Tertiary hospital in Brisbane, Australia. Newly diagnosed patients who were referred for the diagnosis, and/or treatment of head and neck cancer. Quality of life was measured by the University of Washington Quality of Life Survey, version 4 (UW-QoL). Participants completed the UW-QoL questionnaire prior to starting treatment, 1 month and 6 months post treatment. Metropolitan and regional or remote status was classified according to the Australian Standard Geographic Classification-Remoteness Area system. Ninety-five participants were included at baseline; 49 and 41 participants completed the 1-month and 6-month follow-ups, respectively. Scores in most UW-QoL domains decreased between baseline and 1 month post treatment and increased towards pre-treatment scores at the 6-month follow-up (except for anxiety and saliva). Pain at baseline was significantly worse in the regional-remote participants compared with metropolitan participants. No other statistically significant differences in UW-QoL score by geographical location were observed. The findings generally did not support significant differences in quality of life outcome between metropolitan and regional-remote head and neck cancer patients. The difference in pain experience between metropolitan and regional-remote groups requires further investigation. © 2018 National Rural Health Alliance Ltd.

  4. Baseline participation in a health examination survey of the population 65 years and older: who is missed and why?

    PubMed

    Gaertner, Beate; Seitz, Ina; Fuchs, Judith; Busch, Markus A; Holzhausen, Martin; Martus, Peter; Scheidt-Nave, Christa

    2016-01-19

    Public health monitoring depends on valid health and disability estimates in the population 65+ years. This is hampered by high non-participation rates in this age group. There is limited insight into size and direction of potential baseline selection bias. We analyzed baseline non-participation in a register-based random sample of 1481 inner-city residents 65+ years, invited to a health examination survey according to demographics available for the entire sample, self-report information as available and reasons for non-participation. One year after recruitment, non-responders were revisited to assess their reasons. Five groups defined by participation status were differentiated: participants (N = 299), persons who had died or moved (N = 173), those who declined participation, but answered a short questionnaire (N = 384), those who declined participation and the short questionnaire (N = 324), and non-responders (N = 301). The results confirm substantial baseline selection bias with significant underrepresentation of persons 85+ years, persons in residential care or from disadvantaged neighborhoods, with lower education, foreign citizenship, or lower health-related quality of life. Finally, reasons for non-participation could be identified for 78% of all non-participants, including 183 non-responders. A diversity in health problems and barriers to participation exists among non-participants. Innovative study designs are needed for public health monitoring in aging populations.

  5. Baseline Q-values for streams in intensive agricultural catchments in Ireland

    NASA Astrophysics Data System (ADS)

    Melland, Alice; Jordan, Phil; Wall, David; Mellander, Per-Erik; Mechan, Sarah; Shortle, Ger

    2010-05-01

    The effectiveness of regulations introduced in Ireland in 2006 in response to the European Union Nitrates Directives for minimising nutrient loss to waterways from farms is being studied by Teagasc, the Irish Agriculture and Food Development Authority as part of an Agricultural Catchments Programme from 2008 - 2011. The regulations in Ireland require that during winter, green cover is established and maintained on arable farms, manure is stored and not spread, ploughing is not conducted and that chemical fertiliser is not spread. The regulations also require buffer zones between fields and water courses when applying organic or chemical fertilisers and that nutrient application rates and timing match crop requirements. An upper limit for livestock manure loading of 170 kg ha-1 organic N each year is also set. The biophysical research component of the Agricultural Catchments Programme is focussed on quantifying nutrient source availability, surface and subsurface transport pathways and stream chemical water quality. A baseline description of stream ecological quality was also sought. Stream ecology was measured in autumn 2009 at 3-5 locations within four surface water catchments and at the spring emergence of a catchment underlain by karst limestone. Landuse in each catchment is dominated by medium to high intensity grassland or cereal farming and annual average rainfall ranges from 900 - 1200 mm. Surveys were conducted in 1st to 3rd order streams throughout each catchment at locations which had minimal observed point source inputs for 100m upstream, incomplete shade, a hard streambed substrate and riffle conditions suitable for the sampling methods. Benthic macroinvertebrates were identified and quantified and used to calculate the biological indices Small Stream Risk Score, Q-value, Biological Monitoring Working Party (BMWP), Average Score Per Taxa (ASPT) and EQR (Observed Q-value/Reference Q-value). Diatom community assemblages were identified from samples

  6. [Cognitive and quality of life trajectory after either surgical or transcatheter aortic valve replacement in high-risk patients].

    PubMed

    Ciuca, Cristina; Fortuna, Daniela; Ferrari, Susy; Salizzoni, Stefano; Grisoglio, Enrica; Punta, Giuseppe; Del Ponte, Stefano; Aranzulla, Tiziana Claudia; Gabbieri, Davide; Gandolfo, Caterina; Dispensa, Flavia; Vecchio Verderame, Lavinia; Tamburino, Corrado; Caruso, Cinzia; Grossi, Claudio; Mikus, Elisa; Guiducci, Vincenzo; Violini, Roberto; Rongoni, Silvia; Pandolfi, Claudia; Moretti, Carolina; De Palma, Rossana; Chattat, Rabih; Savini, Carlo; Marzocchi, Antonio; Saia, Francesco

    2016-12-01

    The impact of transcatheter aortic valve implantation (TAVI) or surgical aortic valve replacement (AVR) on cognitive status and quality of life in high-risk patients has been incompletely investigated. We conducted a prospective, multicenter study including all patients treated with TAVI and high-risk patients undergoing AVR (age ≥80 years or logistic EuroSCORE ≥15%) at participating centers. Multidimensional geriatric evaluation including Mini Mental State Examination (MMSE), EuroQol 5D (EQ5D) and Minnesota Living With Heart Failure Questionnaire (MLHFQ) were performed at baseline and at 3- and 12-month follow-up. A total of 518 patients (151 AVR and 367 TAVI) were enrolled in 10 Italian institutions. Patients receiving AVR were older (82.7 ± 2.4 years), with a lower logistic EuroSCORE (12.5 ± 7.1%) as compared with TAVI patients (81.5 ± 6.2 years and 19.6 ± 14.0%, respectively, p=0.001 and p<0.001). Overall, 35.5% of patients showed some degree of cognitive impairment at baseline, with no differences between groups. No significant changes in the cognitive status were observed between baseline and follow-up and between groups at any time point. TAVI patients had a lower quality of life at baseline as compared with AVR patients. Generic and heart failure-related quality of life improved significantly after either procedure. In high-risk patients, both TAVI and AVR are associated with a significant improvement of quality of life up to 1 year without a detrimental effect on cognitive function.

  7. Multiple-Baseline Detection of a Geostationary Satellite with the Navy Precision Optical Interferometer

    DTIC Science & Technology

    2015-01-01

    Multiple-baseline detection of a geostationary satellite with the Navy Precision Optical Interferometer J. Thomas Armstronga, Ellyn K. Bainesa...observations of a geostationary satellite using the Navy Precision Optical Inter- ferometer (NPOI) during the glint season of March 2015. We succeeded in...the second night. These baseline lengths correspond to a resolution of ∼4 m at geostationary altitude. This is the first multiple-baseline

  8. Baseline Maritime Aerosol: Methodology to Derive the Optical Thickness and Scattering Properties

    NASA Technical Reports Server (NTRS)

    Kaufman, Yoram J.; Smirnov, Alexander; Holben, Brent N.; Dubovik, Oleg; Einaudi, Franco (Technical Monitor)

    2001-01-01

    Satellite Measurements of the global distribution of aerosol and their effect on climate should be viewed in respect to a baseline aerosol. In this concept, concentration of fine mode aerosol particles is elevated above the baseline by man-made activities (smoke or urban pollution), while coarse mode by natural processes (e.g. dust or sea-spray). Using 1-3 years of measurements in 10 stations of the Aerosol Robotic network (ACRONET we develop a methodology and derive the optical thickness and properties of this baseline aerosol for the Pacific and Atlantic Oceans. Defined as the median for periods of stable optical thickness (standard deviation < 0.02) during 2-6 days, the median baseline aerosol optical thickness over the Pacific Ocean is 0.052 at 500 am with Angstrom exponent of 0.77, and 0.071 and 1.1 respectively, over the Atlantic Ocean.

  9. The Health-Related Quality of Life Journey of Gynecologic Oncology Surgical Patients: Implications for the incorporation of patient-reported outcomes into surgical quality metrics

    PubMed Central

    Doll, Kemi M.; Barber, Emma L.; Bensen, Jeannette T.; Snavely, Anna C.; Gehrig, Paola A.

    2016-01-01

    Objective To report the changes in patient-reported quality of life for women undergoing gynecologic oncology surgeries. Methods In a prospective cohort study from 10/2013-10/2014, women were enrolled pre-operatively and completed comprehensive interviews at baseline, 1, 3, and 6 months post-operatively. Measures included the disease-specific Functional Assessment of Cancer Therapy-General (FACT-GP), general Patient Reported Outcome Measure Information System (PROMIS) global health and validated measures of anxiety and depression. Bivariate statistics were used to analyze demographic groups and changes in mean scores over time. Results Of 231 patients completing baseline interviews, 185 (80%) completed 1-month, 170 (74%) 3-month, and 174 (75%) 6-month interviews. Minimally invasive (n=115, 63%) and laparotomy (n=60, 32%) procedures were performed. Functional wellbeing (20 -> 17.6, p<.0001) decreased at 1-month, and recovered by 3 and 6 months. Emotional wellbeing increased (16.3 -> 20.1, p<.0001) and anxiety decreased (54.2 -> 49.0, p<.0001) at 1-month, and were stable at 3 and 6 months. Physical wellbeing scales were not sensitive to surgery. These patterns were consistent across procedure type, cancer diagnosis, and adjuvant therapy administration. In an exploratory analysis of the interaction of QOL and quality, patients with increased postoperative healthcare resource use were noted to have higher baseline levels of anxiety. Conclusions For women undergoing gynecologic oncology procedures, temporary declines in functional wellbeing are balanced by improvements in emotional wellbeing and decreased anxiety symptoms after surgery. Not all commonly used QOL surveys are sensitive to changes during the perioperative period and may not be suitable for use in surgical quality metrics. PMID:26957479

  10. Baseline modeling of the Owensboro cable-stayed bridge over the Ohio River.

    DOT National Transportation Integrated Search

    2006-03-01

    This report presents the baseline modeling of the Owensboro cable-stayed bridge which connects Owensboro, Kentucky and Rockport, Indiana over the Ohio River. The objective of this study is to establish the bridge baseline model via the dynamics-based...

  11. Baseline concentration of 210Po in Kuwait's commercial fish species.

    PubMed

    Uddin, S; Al-Ghadban, A N; Behbehani, M; Aba, A; Al Mutairi, A; Karam, Q

    2012-11-01

    This baseline study highlights the (210)Po variation in whole fishes with different feeding habits. Whole-body (210)Po concentrations were determined in ten important commercial fish species found in the northern Arabian Gulf to serve as baseline data. Primarily, (210)Po is absorbed from water, concentrated by phytoplankton and microzooplankton, and then transferred to the next trophic level along the marine food chain. The lowest concentration of (210)Po was measured in larger carnivorous fishes like hamoor (0.089 Bq kg(-1)), while the highest was found in the fishes that feed on algae, zooplanktons and detritus, like battan (3.30 Bq kg(-1)). The baseline data can be used to understand both the trophic transfer of (210)Po in the marine food chain and the (210)Po concentration factors in fish from the Arabian Gulf. Copyright © 2012 Elsevier Ltd. All rights reserved.

  12. NREL Solar Radiation Research Laboratory (SRRL): Baseline Measurement System (BMS); Golden, Colorado (Data)

    DOE Data Explorer

    Stoffel, T.; Andreas, A.

    1981-07-15

    The SRRL was established at the Solar Energy Research Institute (now NREL) in 1981 to provide continuous measurements of the solar resources, outdoor calibrations of pyranometers and pyrheliometers, and to characterize commercially available instrumentation. The SRRL is an outdoor laboratory located on South Table Mountain, a mesa providing excellent solar access throughout the year, overlooking Denver. Beginning with the basic measurements of global horizontal irradiance, direct normal irradiance and diffuse horizontal irradiance at 5-minute intervals, the SRRL Baseline Measurement System now produces more than 130 data elements at 1-min intervals that are available from the Measurement & Instrumentation Data Center Web site. Data sources include global horizontal, direct normal, diffuse horizontal (from shadowband and tracking disk), global on tilted surfaces, reflected solar irradiance, ultraviolet, infrared (upwelling and downwelling), photometric and spectral radiometers, sky imagery, and surface meteorological conditions (temperature, relative humidity, barometric pressure, precipitation, snow cover, wind speed and direction at multiple levels). Data quality control and assessment include daily instrument maintenance (M-F) with automated data quality control based on real-time examinations of redundant instrumentation and internal consistency checks using NREL's SERI-QC methodology. Operators are notified of equipment problems by automatic e-mail messages generated by the data acquisition and processing system. Radiometers are recalibrated at least annually with reference instruments traceable to the World Radiometric Reference (WRR).

  13. A Randomized Clinical Trial of the Effects of Parent Mentors on Early Childhood Obesity: Study Design and Baseline Data

    PubMed Central

    Foster, Byron A.; Aquino, Christian; Gil, Mario; Flores, Glenn; Hale, Daniel

    2015-01-01

    Background Few effective community-based interventions exist for early childhood obesity. Parent mentors have been successful as an intervention for other conditions, but have not been used for childhood obesity. We designed an intervention for early childhood obesity using parent mentors and a positive outlier approach to assess potential efficacy, feasibility, and acceptability. Methods This trial enrolled obese (≥95th BMI percentile for age and gender) 2-5-year-old children in a Head Start program and their parents, with allocation to either parent mentors trained in positively deviant behaviors regarding childhood obesity, or community health workers delivering health education on obesity-related behaviors. The primary outcome is body mass index z-score change at the six-month follow-up assessment. Secondary outcomes include feeding behaviors and practices, health-related quality of life, dietary intake, and participation levels. Results We enrolled three parent mentors and 60 parent-child dyads. The population is 100% Hispanic; 44% of parents speak Spanish as their primary language and 45% were not high-school graduates. Children had a reported median vegetable and fruit intake of 0.3 and 1.1 cups per day, respectively, at baseline, and a median daily screen time of three hours. There was no intergroup difference in quality-of-life scores at baseline. Retention has been high, at 90% at three months. Conclusions In this randomized trial of the effects of parent mentors on early childhood obesity, parent-child dyads from an underserved, Hispanic population were successfully enrolled through a partnership with a Head Start organization, with a high retention rate. PMID:26343746

  14. Restless legs syndrome after high-risk TIA and minor stroke: association with reduced quality of life.

    PubMed

    Boulos, Mark I; Wan, Anthony; Black, Sandra E; Lim, Andrew S; Swartz, Richard H; Murray, Brian J

    2017-09-01

    Restless legs syndrome (RLS) is a movement disorder that is associated with poor quality of life and depressive symptoms in the general population. Emerging evidence suggests that RLS is closely associated with cerebrovascular disease. We assessed the effect of RLS on quality of life after stroke and transient ischemic attack (TIA). In this single-center prospective study, we recruited patients within 14 days of high-risk TIA or minor stroke. Patients were diagnosed with RLS using a questionnaire based on the 2003 International RLS Study Group criteria, and diagnoses were confirmed by a sleep neurologist. Follow-up assessments were conducted within 2-6 months of recruitment. The outcome of quality of life was measured using the Stroke-specific Quality of Life (SS-QoL). Of the 94 patients recruited into the study, 23 (24.4%) were diagnosed with RLS: 11 were newly diagnosed with RLS and 12 had RLS preceding the index stroke/TIA. There were no significant differences in baseline characteristics between those with or without RLS. Median SS-QoL in patients with RLS was lower at baseline (p = 0.008) and at follow-up (p = 0.002). RLS patients had more depressive symptoms at follow-up (p = 0.007). Ordinal logistic regression demonstrated that RLS was negatively associated with quality of life at baseline (OR = 0.28; p = 0.010) and at follow-up (OR = 0.14; p = 0.029), independent of functional outcome and depressive symptoms. RLS is common after stroke or TIA and negatively affects the quality of life. Screening for RLS after cerebrovascular events may be warranted, and future research should assess whether treatment of RLS can improve post-stroke quality of life. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. 76 FR 8725 - Notice of Baseline Filings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-15

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Notice of Baseline Filings Enstor Grama Ridge Storage and Docket No. PR10-97-002. Transportation, L.L.C.. EasTrans, LLC Docket No. PR10-30-001. DCP Guadalupe Pipeline, LLC...... Docket No. PR10-31-002. DCP Raptor Pipeline, LLC......... Docket No...

  16. Baseline Evaluations to Support Control Room Modernization at Nuclear Power Plants

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Boring, Ronald L.; Joe, Jeffrey C.

    2015-02-01

    For any major control room modernization activity at a commercial nuclear power plant (NPP) in the U.S., a utility should carefully follow the four phases prescribed by the U.S. Nuclear Regulatory Commission in NUREG-0711, Human Factors Engineering Program Review Model. These four phases include Planning and Analysis, Design, Verification and Validation, and Implementation and Operation. While NUREG-0711 is a useful guideline, it is written primarily from the perspective of regulatory review, and it therefore does not provide a nuanced account of many of the steps the utility might undertake as part of control room modernization. The guideline is largely summative—intendedmore » to catalog final products—rather than formative—intended to guide the overall modernization process. In this paper, we highlight two crucial formative sub-elements of the Planning and Analysis phase specific to control room modernization that are not covered in NUREG-0711. These two sub-elements are the usability and ergonomics baseline evaluations. A baseline evaluation entails evaluating the system as-built and currently in use. The usability baseline evaluation provides key insights into operator performance using the control system currently in place. The ergonomics baseline evaluation identifies possible deficiencies in the physical configuration of the control system. Both baseline evaluations feed into the design of the replacement system and subsequent summative benchmarking activities that help ensure that control room modernization represents a successful evolution of the control system.« less

  17. Qualities of Sore Throat Index (QuaSTI): measuring descriptors of sore throat in a randomized, placebo-controlled trial.

    PubMed

    Schachtel, Bernard; Shephard, Adrian; Schachtel, Emily; Lorton, Mary Beth; Shea, Tim; Aspley, Sue

    2018-03-01

    Patients with pharyngitis often describe various sensory, affective and evaluative pain qualities. Using an 11-word/phrase index, the Qualities of Sore Throat Index (QuaSTI), we characterized throat symptoms and evaluated changes in a randomized controlled trial (NCT01986361). Patients received a single flurbiprofen 8.75 mg (n = 101) or placebo (n = 21) lozenge and rated throat soreness at baseline and regular intervals over 3 h, and the QuaSTI at baseline, 1, 2 and 3 h post-treatment. The QuaSTI distinguished active drug from placebo and detected clinically important (≥2-point) changes over 3 h. Mean change from baseline over 3 h was significantly greater for flurbiprofen (154%) than placebo (p < 0.05). The QuaSTI is a sensitive instrument for measuring therapeutic effects in patients with pharyngitis.

  18. Baseline modeling of the Maysville cable-stayed bridge over the Ohio River.

    DOT National Transportation Integrated Search

    2005-07-01

    This report presents the baseline modeling of the Maysville cable-stayed bridge which connects Maysville, Kentucky and Aberdeen, Ohio over the Ohio River. The objective of this study is to establish the bridge baseline model via the dynamics-based te...

  19. A model for the Holocene extinction of the mammal megafauna in Ecuador

    NASA Astrophysics Data System (ADS)

    Ficcarelli, G.; Coltorti, M.; Moreno-Espinosa, M.; Pieruccini, P. L.; Rook, L.; Torre, D.

    2003-03-01

    This paper presents the results of multidisciplinary research in the Ecuadorian coastal regions, with particular emphasis on the Santa Elena Peninsula. The new evidence, together with previous data gathered on the Ecuadorian cordillera during the last 12 years, allows us to formulate a model that accounts for most of the mammal megafauna extinction at the Pleistocene/Holocene transition. After the illustration of geomorphological and paleontological evidences of the area of the Santa Elena Peninsula (and other sites), and of a summary of the paleoclimatic data, the main results and conclusions of this work are: (1) Late Pleistocene mammal assemblages survived in the Ecuadorian coast until the Early Holocene sea level rise; (2) Prior to the extinction of most of the megafauna elements (mastodons, ground sloths, equids, sabre-tooth felids), the mammal communities at Santa Elena Peninsula comprise elements with differing habitat requirements, attesting conditions of high biological pressure; (3) At the El Cautivo site (Santa Elena Peninsula), we have discovered Holocene sediments containing the first known occurrences in Ecuador of lithic artifacts that are associated with mammal megafauna remains; (4) During the last 10,000 years, the coastal region of Ecuador underwent significant changes in vegetation cover. At the Pleistocene/Holocene transition the climate changed from very arid conditions to humid conditions. Our data indicates that the megafauna definitively abandoned the Cordillera areas around 12,000 yr BP due to t he increasing aridity, and subsequently migrated to coastal areas where ecological conditions still were suitable, Santa Elena Peninsula and mainly Amazonian areas being typical. We conclude that the unusual high faunal concentrations and the change to dense vegetation cover (due to a rapid increase in precipitation in the lower Holocene) at 8000-6000 yr BP, caused the final collapse and extinction of most elements of the mammal megafauna

  20. Analysis of early accountable care organizations defines patient, structural, cost, and quality-of-care characteristics.

    PubMed

    Epstein, Arnold M; Jha, Ashish K; Orav, E John; Liebman, Daniel L; Audet, Anne-Marie J; Zezza, Mark A; Guterman, Stuart

    2014-01-01

    Accountable care organizations (ACOs) have attracted interest from many policy makers and clinical leaders because of their potential to improve the quality of care and reduce costs. Federal ACO programs for Medicare beneficiaries are now up and running, but little information is available about the baseline characteristics of early entrants. In this descriptive study we present data on the structural and market characteristics of these early ACOs and compare ACOs' patient populations, costs, and quality with those of their non-ACO counterparts at baseline. We found that ACO patients were more likely than non-ACO patients to be older than age eighty and had higher incomes. ACO patients were less likely than non-ACO patients to be black, covered by Medicaid, or disabled. The cost of care for ACO patients was slightly lower than that for non-ACO patients. Slightly fewer than half of the ACOs had a participating hospital. Hospitals that were in ACOs were more likely than non-ACO hospitals to be large, teaching, and not-for-profit, although there was little difference in their performance on quality metrics. Our findings can be useful in interpreting the early results from the federal ACO programs and in establishing a baseline to assess the programs' development.

  1. GNSS Single Frequency, Single Epoch Reliable Attitude Determination Method with Baseline Vector Constraint.

    PubMed

    Gong, Ang; Zhao, Xiubin; Pang, Chunlei; Duan, Rong; Wang, Yong

    2015-12-02

    For Global Navigation Satellite System (GNSS) single frequency, single epoch attitude determination, this paper proposes a new reliable method with baseline vector constraint. First, prior knowledge of baseline length, heading, and pitch obtained from other navigation equipment or sensors are used to reconstruct objective function rigorously. Then, searching strategy is improved. It substitutes gradually Enlarged ellipsoidal search space for non-ellipsoidal search space to ensure correct ambiguity candidates are within it and make the searching process directly be carried out by least squares ambiguity decorrelation algorithm (LAMBDA) method. For all vector candidates, some ones are further eliminated by derived approximate inequality, which accelerates the searching process. Experimental results show that compared to traditional method with only baseline length constraint, this new method can utilize a priori baseline three-dimensional knowledge to fix ambiguity reliably and achieve a high success rate. Experimental tests also verify it is not very sensitive to baseline vector error and can perform robustly when angular error is not great.

  2. Getting started on metrics - Jet Propulsion Laboratory productivity and quality

    NASA Technical Reports Server (NTRS)

    Bush, M. W.

    1990-01-01

    A review is presented to describe the effort and difficulties of reconstructing fifteen years of JPL software history. In 1987 the collection and analysis of project data were started with the objective of creating laboratory-wide measures of quality and productivity for software development. As a result of this two-year Software Product Assurance metrics study, a rough measurement foundation for software productivity and software quality, and an order-of-magnitude quantitative baseline for software systems and subsystems are now available.

  3. Evidence for baseline glucocorticoids as mediators of reproductive investment in a wild bird.

    PubMed

    Love, Oliver P; Madliger, Christine L; Bourgeon, Sophie; Semeniuk, Christina A D; Williams, Tony D

    2014-04-01

    Determining the mechanisms that mediate investment decisions between current and future reproductive attempts is still a key goal of life-history studies. Since baseline levels of stress hormones (glucocorticoids - GCs) act as predictive and labile regulators of daily energetic balance in vertebrates they remain excellent candidates for mediating investment decisions both within and across reproductive attempts. Using free-living female European starlings (Sturnus vulgaris) we experimentally reduced investment in current reproduction (number of offspring raised in the first brood) to examine whether baseline corticosterone (CORT) acted as a hormonal mediator preparing individuals for a predictable increase in future investment (number of offspring raised in the second brood). Although treatment and control birds raised the same total amount of offspring across two broods, the experimental birds increased reproductive investment in second broods to compensate for the reduced investment in the first brood. Data on both mean and intra-individual changes in baseline CORT support the idea that an increase in baseline CORT between the incubation stages in treatment birds strongly predicted this increase in investment. Importantly, we measured the increase in baseline CORT during late incubation prior to the increase in energetic demand associated with increased reproductive investment in offspring, indicating that flexible within-individual changes in baseline GCs can act as a labile mechanism preparing individuals for predictable increases in reproductive investment. As such, our experimental results indicate that elevated baseline GCs can prepare individuals for investment in energetically expensive life-history stages, rather than simply being elevated as a consequence of increased effort or demand. This suggests that short-term preparative increases in baseline GCs benefit individuals by successfully allowing them to maximize fitness under varying environmental

  4. Classification of baseline toxicants for QSAR predictions to replace fish acute toxicity studies.

    PubMed

    Nendza, Monika; Müller, Martin; Wenzel, Andrea

    2017-03-22

    Fish acute toxicity studies are required for environmental hazard and risk assessment of chemicals by national and international legislations such as REACH, the regulations of plant protection products and biocidal products, or the GHS (globally harmonised system) for classification and labelling of chemicals. Alternative methods like QSARs (quantitative structure-activity relationships) can replace many ecotoxicity tests. However, complete substitution of in vivo animal tests by in silico methods may not be realistic. For the so-called baseline toxicants, it is possible to predict the fish acute toxicity with sufficient accuracy from log K ow and, hence, valid QSARs can replace in vivo testing. In contrast, excess toxicants and chemicals not reliably classified as baseline toxicants require further in silico, in vitro or in vivo assessments. Thus, the critical task is to discriminate between baseline and excess toxicants. For fish acute toxicity, we derived a scheme based on structural alerts and physicochemical property thresholds to classify chemicals as either baseline toxicants (=predictable by QSARs) or as potential excess toxicants (=not predictable by baseline QSARs). The step-wise approach identifies baseline toxicants (true negatives) in a precautionary way to avoid false negative predictions. Therefore, a certain fraction of false positives can be tolerated, i.e. baseline toxicants without specific effects that may be tested instead of predicted. Application of the classification scheme to a new heterogeneous dataset for diverse fish species results in 40% baseline toxicants, 24% excess toxicants and 36% compounds not classified. Thus, we can conclude that replacing about half of the fish acute toxicity tests by QSAR predictions is realistic to be achieved in the short-term. The long-term goals are classification criteria also for further groups of toxicants and to replace as many in vivo fish acute toxicity tests as possible with valid QSAR

  5. Baseline impedance measured during high-resolution esophageal impedance manometry reliably discriminates GERD patients.

    PubMed

    Ravi, K; Geno, D M; Vela, M F; Crowell, M D; Katzka, D A

    2017-05-01

    Baseline impedance measured with ambulatory impedance pH monitoring (MII-pH) and a mucosal impedance catheter detects gastroesophageal reflux disease (GERD). However, these tools are limited by cost or patient tolerance. We investigated whether baseline impedance measured during high-resolution impedance manometry (HRIM) distinguishes GERD patients from controls. Consecutive patients with clinical HRIM and MII-pH testing were identified. Gastroesophageal reflux disease was defined by esophageal pH <4 for ≥5% of both the supine and total study time, whereas controls had an esophageal pH <4 for ≤3% of the study performed off PPI. Baseline impedance was measured over 15 seconds during the landmark period of HRIM and over three 10 minute intervals during the overnight period of MII-pH. Among 29 GERD patients and 26 controls, GERD patients had a mean esophageal acid exposure time of 22.7% compared to 1.2% in controls (P<.0001). Mean baseline impedance during HRIM was lower in GERD (1061 Ω) than controls (2814 Ω) (P<.0001). Baseline mucosal impedance measured during HRIM and MII-pH correlated (r=0.59, P<.0001). High-resolution esophageal manometry baseline impedance had high diagnostic accuracy for GERD, with an area under the curve (AUC) of 0.931 on receiver operating characteristics (ROC) analysis. A HRIM baseline impedance threshold of 1582 Ω had a sensitivity of 86.2% and specificity of 88.5% for GERD, with a positive predictive value of 89.3% and negative predictive value of 85.2%. Baseline impedance measured during HRIM can reliably discriminate GERD patients with at least moderate esophageal acid exposure from controls. This diagnostic tool may represent an accurate, cost-effective, and less invasive test for GERD. © 2016 John Wiley & Sons Ltd.

  6. The selection of the optimal baseline in the front-view monocular vision system

    NASA Astrophysics Data System (ADS)

    Xiong, Bincheng; Zhang, Jun; Zhang, Daimeng; Liu, Xiaomao; Tian, Jinwen

    2018-03-01

    In the front-view monocular vision system, the accuracy of solving the depth field is related to the length of the inter-frame baseline and the accuracy of image matching result. In general, a longer length of the baseline can lead to a higher precision of solving the depth field. However, at the same time, the difference between the inter-frame images increases, which increases the difficulty in image matching and the decreases matching accuracy and at last may leads to the failure of solving the depth field. One of the usual practices is to use the tracking and matching method to improve the matching accuracy between images, but this algorithm is easy to cause matching drift between images with large interval, resulting in cumulative error in image matching, and finally the accuracy of solving the depth field is still very low. In this paper, we propose a depth field fusion algorithm based on the optimal length of the baseline. Firstly, we analyze the quantitative relationship between the accuracy of the depth field calculation and the length of the baseline between frames, and find the optimal length of the baseline by doing lots of experiments; secondly, we introduce the inverse depth filtering technique for sparse SLAM, and solve the depth field under the constraint of the optimal length of the baseline. By doing a large number of experiments, the results show that our algorithm can effectively eliminate the mismatch caused by image changes, and can still solve the depth field correctly in the large baseline scene. Our algorithm is superior to the traditional SFM algorithm in time and space complexity. The optimal baseline obtained by a large number of experiments plays a guiding role in the calculation of the depth field in front-view monocular.

  7. PAH Baselines for Amazonic Surficial Sediments: A Case of Study in Guajará Bay and Guamá River (Northern Brazil).

    PubMed

    Rodrigues, Camila Carneiro Dos Santos; Santos, Ewerton; Ramos, Brunalisa Silva; Damasceno, Flaviana Cardoso; Correa, José Augusto Martins

    2018-06-01

    The 16 priority PAH were determined in sediment samples from the insular zone of Guajará Bay and Guamá River (Southern Amazon River mouth). Low hydrocarbon levels were observed and naphthalene was the most representative PAH. The low molecular weight PAH represented 51% of the total PAH. Statistical analysis showed that the sampling sites are not significantly different. Source analysis by PAH ratios and principal component analysis revealed that PAH are primary from a few rate of fossil fuel combustion, mainly related to the local small community activity. All samples presented no biological stress or damage potencial according to the sediment quality guidelines. This study discuss baselines for PAH in surface sediments from Amazonic aquatic systems based on source determination by PAH ratios and principal component analysis, sediment quality guidelines and through comparison with previous studies data.

  8. Prospective associations of social isolation and loneliness with poor sleep quality in older adults.

    PubMed

    Yu, Bin; Steptoe, Andrew; Niu, Kaijun; Ku, Po-Wen; Chen, Li-Jung

    2018-03-01

    There is evidence for negative associations between social isolation and loneliness and sleep quality in older adults. However, it is unclear to what extent these two factors independently affect sleep quality. This study examined the simultaneous associations of social isolation and loneliness with sleep quality in a longitudinal study of older adults. Data were analyzed from the Social Environment and Biomarkers of Aging Study in Taiwan collected in 2000 and 2006, involving a cohort of 639 participants (mean age = 66.14, SD 7.26). Poisson regression models were conducted to examine the association of social isolation and/or loneliness with sleep quality at follow-up after adjusting for multiple confounding variables. Univariate analysis showed that sleep quality was inversely associated with both social isolation and loneliness. After demographic, health, cognitive factors, and depressive symptoms were controlled in multivariable analysis, social isolation at the baseline still predicted poor sleep quality 6 years later (incident rate ratio, IRR 1.14; 95% CI 1.04-1.24; p < 0.01), while the association between loneliness and sleep quality was no longer significant (IRR 1.08; 95% CI 0.94-1.23; p = 0.27). The results were unchanged when participants who had poor sleep quality at the baseline were excluded from the analysis. These findings confirm an adverse effect of social isolation on the sleep quality of older adults, but indicate that this effect is independent of loneliness. Social isolation and loneliness seem to have distinct pathways in affecting the sleep quality of older adults.

  9. Self-Perceived Quality of Life Among Patients with Alzheimer's Disease: Two Longitudinal Models of Analysis.

    PubMed

    Conde-Sala, Josep L; Turró-Garriga, Oriol; Portellano-Ortiz, Cristina; Viñas-Diez, Vanesa; Gascón-Bayarri, Jordi; Reñé-Ramírez, Ramón

    2016-04-12

    The objective was to analyze the factors that influence self-perceived quality of life (QoL) in patients with Alzheimer's disease (AD), contrasting two different longitudinal models. A total of 127 patients were followed up over 24 months. The instruments applied were: Quality of Life in Alzheimer's Disease scale (QoL-AD), Geriatric Depression Scale-15, Anosognosia Questionnaire-Dementia, Disability Assessment in Dementia, Neuropsychiatric Inventory, and the Mini-Mental State Examination. Two models for grouping patients were tested: 1) Baseline score on the QoL-AD (QoL-Baseline), and 2) Difference in QoL-AD score between baseline and follow-up (QoL-Change). Generalized estimating equations were used to analyze longitudinal data, and multinomial regression analyses were performed. Over the follow-up period the QoL-Baseline model showed greater variability between groups (Wald χ2 = 172.3, p < 0.001) than did the QoL-Change model (Wald χ2  = 1.7, p = 0.427). In the QoL-Baseline model the predictive factors were greater depression (odds ratio [OR] = 1.20; 95% CI: 1.00- 1.45) and lower functional ability (OR = 0.92; 95% CI: 0.85- 0.99) for the Low QoL group (< 33 QoL-AD), and less depression (OR = 0.68; 95% CI: 0.52- 0.88), more anosognosia (OR = 1.07; 95% CI: 1.01- 1.13), and fewer neuropsychiatric symptoms (OR = 0.95; 95% CI: 0.91- 0.99) for the High-QoL group (>37 QoL-AD). The model based on baseline scores (QoL-Baseline) was better than the QoL-Change model in terms of identifying trajectories and predictors of QoL in AD.

  10. The Relationship of Engagement in Improvement Practices to Outcome Measures in Large-Scale Quality Improvement Initiatives.

    PubMed

    Foster, Gregory L; Kenward, Kevin; Hines, Stephen; Joshi, Maulik S

    Hospital engagement networks (HENs) are part of the largest health care improvement initiative ever undertaken. This article explores whether engagement in improvement activities within a HEN affected quality measures. Data were drawn from 1174 acute care hospitals. A composite quality score was created from 10 targeted topic area measures multiplied by the number of qualifying topics. Scores improved from 5.4 (SD = 6.8) at baseline to 4.6 (5.9) at remeasurement; P < .0001. Hospitals with higher baseline scores demonstrated greater improvement ( P < .0001) than hospitals with lower baseline scores. Hospitals with larger Medicaid populations ( P = .023) and micropolitan ( P = .034) hospitals tended to have greater improvement, whereas hospitals in the West ( P = .0009) did not improve as much as hospitals in other regions. After adjusting for hospital characteristics, hospitals with improvement champions ( P = .008), a higher level of engagement with their state association ( P = .001), and more leadership involvement ( P = .005) in HEN demonstrated greater improvement.

  11. Localizing gravitational wave sources with single-baseline atom interferometers

    DOE PAGES

    Graham, Peter W.; Jung, Sunghoon

    2018-01-31

    Localizing sources on the sky is crucial for realizing the full potential of gravitational waves for astronomy, astrophysics, and cosmology. Here in this paper, we show that the midfrequency band, roughly 0.03 to 10 Hz, has significant potential for angular localization. The angular location is measured through the changing Doppler shift as the detector orbits the Sun. This band maximizes the effect since these are the highest frequencies in which sources live for several months. Atom interferometer detectors can observe in the midfrequency band, and even with just a single baseline they can exploit this effect for sensitive angular localization.more » The single-baseline orbits around the Earth and the Sun, causing it to reorient and change position significantly during the lifetime of the source, and making it similar to having multiple baselines/detectors. For example, atomic detectors could predict the location of upcoming black hole or neutron star merger events with sufficient accuracy to allow optical and other electromagnetic telescopes to observe these events simultaneously. Thus, midband atomic detectors are complementary to other gravitational wave detectors and will help complete the observation of a broad range of the gravitational spectrum.« less

  12. Localizing gravitational wave sources with single-baseline atom interferometers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Graham, Peter W.; Jung, Sunghoon

    Localizing sources on the sky is crucial for realizing the full potential of gravitational waves for astronomy, astrophysics, and cosmology. Here in this paper, we show that the midfrequency band, roughly 0.03 to 10 Hz, has significant potential for angular localization. The angular location is measured through the changing Doppler shift as the detector orbits the Sun. This band maximizes the effect since these are the highest frequencies in which sources live for several months. Atom interferometer detectors can observe in the midfrequency band, and even with just a single baseline they can exploit this effect for sensitive angular localization.more » The single-baseline orbits around the Earth and the Sun, causing it to reorient and change position significantly during the lifetime of the source, and making it similar to having multiple baselines/detectors. For example, atomic detectors could predict the location of upcoming black hole or neutron star merger events with sufficient accuracy to allow optical and other electromagnetic telescopes to observe these events simultaneously. Thus, midband atomic detectors are complementary to other gravitational wave detectors and will help complete the observation of a broad range of the gravitational spectrum.« less

  13. Localizing gravitational wave sources with single-baseline atom interferometers

    NASA Astrophysics Data System (ADS)

    Graham, Peter W.; Jung, Sunghoon

    2018-02-01

    Localizing sources on the sky is crucial for realizing the full potential of gravitational waves for astronomy, astrophysics, and cosmology. We show that the midfrequency band, roughly 0.03 to 10 Hz, has significant potential for angular localization. The angular location is measured through the changing Doppler shift as the detector orbits the Sun. This band maximizes the effect since these are the highest frequencies in which sources live for several months. Atom interferometer detectors can observe in the midfrequency band, and even with just a single baseline they can exploit this effect for sensitive angular localization. The single-baseline orbits around the Earth and the Sun, causing it to reorient and change position significantly during the lifetime of the source, and making it similar to having multiple baselines/detectors. For example, atomic detectors could predict the location of upcoming black hole or neutron star merger events with sufficient accuracy to allow optical and other electromagnetic telescopes to observe these events simultaneously. Thus, midband atomic detectors are complementary to other gravitational wave detectors and will help complete the observation of a broad range of the gravitational spectrum.

  14. 41 CFR 109-1.5202 - Establishment of a personal property holdings baseline.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... personal property holdings baseline. 109-1.5202 Section 109-1.5202 Public Contracts and Property Management Federal Property Management Regulations System (Continued) DEPARTMENT OF ENERGY PROPERTY MANAGEMENT...-1.5202 Establishment of a personal property holdings baseline. (a) If the contractor is a new...

  15. Can Intensity-Modulated Radiotherapy Preserve Oral Health-Related Quality of Life of Nasopharyngeal Carcinoma Patients?

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pow, Edmond H.N., E-mail: ehnpow@hku.hk; Kwong, Dora L.W.; Sham, Jonathan S.T.

    Purpose: To investigate the changes in salivary function and oral health-related quality of life for patients with nasopharyngeal carcinoma treated by intensity-modulated radiotherapy (IMRT). Methods and Materials: A total of 57 patients with early-stage nasopharyngeal carcinoma received IMRT. The parotid and whole saliva flow was measured, and the Medical Outcomes Study 36-item short form, European Organization for Research and Treatment of Cancer Quality of Life questionnaire-C30, European Organization for Research and Treatment of Cancer Quality of Life questionnaire 35-item head-and-neck module, and Oral Health Impact Profile questionnaires were completed at baseline and 2, 6, 12, 18, and 24 months aftermore » IMRT. Results: Parotid saliva flow recovered fully after 1 year and maintained. Whole saliva flow recovered partially to 40% of baseline. A general trend of deterioration in most quality of life scales was observed after IMRT, followed by gradual recovery. Persistent oral-related symptoms were found 2 years after treatment. Conclusion: IMRT for early-stage nasopharyngeal carcinoma could only partially preserve the whole salivary function and oral health-related quality of life.« less

  16. Effects of land use on surface-water quality in the East Everglades, Dade County, Florida

    USGS Publications Warehouse

    Waller, Bradley G.

    1982-01-01

    Water-quality characteristics were determined at five developed areas in the East Everglades, Dade County, Florida, during the 1978 wet season (June through October). These areas are designated as: Coopertown; Chekika Hammock State Park; residential area; rock-plowed tomato field; and Cracker Jack Slough agricultural area. Data from the developed areas were compared with data from four baseline sites in undeveloped areas to determine the effects of land use on the surface-water quality. The rock-plowed tomato field was the only area where surface-water quality was affected. Water quality at this field is affected by agricultural activities and chemical applications as indicated by increased concentrations of orthophosphate, organic nitrogen, organic carbon, copper, manganese, mercury, and potassium. The remaining four areas of land use had water-quality characteristics typical of baseline sites in nearby Northeast Shark River Slough or Taylor Slough. Chemical analyses of soil indicated chlorinated-hydrocarbon insecticide residues at Coopertown and the two agricultural areas, Cracker Jack Slough and the rock-plowed tomato field. Trace elements in concentrations greater than base level occurred at both agricultural areas (manganese), Chekika Hammock State Park (manganese), and at Coopertown (lead and zinc). (USGS)

  17. Prospective quality of life outcomes following robotic surgery in gynecologic oncology.

    PubMed

    Abitbol, Jeremie; Lau, Susie; Ramanakumar, Agnihotram V; Press, Joshua Z; Drummond, Nancy; Rosberger, Zeev; Aubin, Sylvie; Gotlieb, Raphael; How, Jeffrey; Gotlieb, Walter H

    2014-07-01

    To characterize the health-related quality of life (HRQL) of patients undergoing robotic surgery for the treatment of gynecologic cancers. 211 patients completed a quality of life questionnaire before surgery. Postoperative questionnaires, consisting of the same assessment with the addition of postoperative questions, were given at 1 week, 3 weeks, 3, 6, and 12 months after surgery. The Functional Assessment of Cancer Therapy-General (FACT-G) and its subscales were used to evaluate HRQL. Patient-rated body image was evaluated using the Body Image Scale. Statistical significance was measured by the Wilcoxon signed-rank test. Minimally important difference (MID) values were analyzed to evaluate clinical significance. Overall HRQL and body image decreased at 1 week after surgery and returned to baseline by 3 weeks. Physical and functional well-being decreased at 1 week after surgery and returned to baseline by 3 months after surgery. However, using MID criteria, physical well-being returned to baseline by 3 weeks. Social well-being did not change significantly. Emotional well-being increased immediately by 1 week after surgery. Patient reported HRQL outcomes following robotic surgery for the treatment of gynecologic cancers suggests a rapid return to pre-surgery values. Copyright © 2014 Elsevier Inc. All rights reserved.

  18. Quality process measures for rheumatoid arthritis: performance from members enrolled in a national health plan.

    PubMed

    Tkacz, Joseph; Ellis, Lorie A; Meyer, Roxanne; Bolge, Susan C; Brady, Brenna L; Ruetsch, Charles

    2015-02-01

    Health care quality problems are reflected in the underuse, overuse, and misuse of health care services. There is evidence suggesting that the quality of rheumatoid arthritis (RA) patient care is suboptimal, which has spurred the development of a number of systematic quality improvement metrics. To investigate a quality process measurement set in a sample of commercially insured RA patients. Medical, pharmacy, and laboratory claims for members with an RA diagnosis (ICD-9-CM 714.x) during calendar years 2008 through 2012 were extracted from the Optum Clinformatics Data Mart database. Eight process quality measures focused on RA patient response and tolerance to therapy were examined in the claims database. Measures were calculated for individual calendar years from 2009 to 2012, inclusive. The majority of adult RA patients received at least 1 prescription for a disease-modifying antirheumatic drug (DMARD) across the 4 measurement years: range = 78.5%-81.6%. Erythrocyte sedimentation rate and C-reactive protein testing were also evident in the majority of the sample, with 67.1%-72.2% of newly diagnosed RA patients receiving baseline testing, and 56.0%-58.7% of existing RA patients receiving annual testing. Among methotrexate users, liver function tests were performed in 74.5%-75.7% of treated patients, serum creatinine tests in 70.1%-72.6% of patients, and complete blood count tests in 74.5%-76.0% of patients. Additionally, most patients initiating a new DMARD had a claim for a baseline serum creatinine test (68.0%-70.3%) and baseline liver function test (69.3%-71.0%). Findings suggest that a majority of RA patients are attaining patient quality process measures, although a considerable proportion of patients (approximately 25%) may be receiving suboptimal care. Further studies are warranted to understand whether attainment of these measures translates into better outcomes.

  19. Baseline LAW Glass Formulation Testing

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kruger, Albert A.; Mooers, Cavin; Bazemore, Gina

    2013-06-13

    The major objective of the baseline glass formulation work was to develop and select glass formulations that are compliant with contractual and processing requirements for each of the LAW waste streams. Other objectives of the work included preparation and characterization of glasses with respect to the properties of interest, optimization of sulfate loading in the glasses, evaluation of ability to achieve waste loading limits, testing to demonstrate compatibility of glass melts with melter materials of construction, development of glass formulations to support ILAW qualification activities, and identification of glass formulation issues with respect to contract specifications and processing requirements.

  20. Geotaxis baseline data for Drosophila

    NASA Technical Reports Server (NTRS)

    Schnebel, E. M.; Bhargava, R.; Grossfield, J.

    1987-01-01

    Geotaxis profiles for 20 Drosophila species and semispecies at different ages have been examined using a calibrated, adjustable slant board device. Measurements were taken at 5 deg intervals ranging from 0 deg to 85 deg. Clear strain and species differences are observed, with some groups tending to move upward (- geotaxis) with increasing angles, while others move downward (+ geotaxis). Geotactic responses change with age in some, but not all experimental groups. Sample geotaxis profiles are presented and their application to ecological and aging studies are discussed. Data provide a baseline for future evaluations of the biological effects of microgravity.