Internal quality assurance in a clinical virology laboratory. II. Internal quality control.
Gray, J J; Wreghitt, T G; McKee, T A; McIntyre, P; Roth, C E; Smith, D J; Sutehall, G; Higgins, G; Geraghty, R; Whetstone, R
1995-01-01
AIMS--In April 1991 additional quality control procedures were introduced into the virology section of the Clinical Microbiology and Public Health Laboratory, Cambridge. Internal quality control (IQC) samples were gradually included in the serological assays performed in the laboratory and supplemented kit controls and standard sera. METHODS--From April 1991 to December 1993, 2421 IQC procedures were carried out with reference sera. RESULTS--The IQC samples were evaluated according to the Westgard rules. Violations were recorded in 60 of 1808 (3.3%) controls and were highest in the IQC samples of complement fixation tests (25/312 (8%) of controls submitted for complement fixation tests). CONCLUSIONS--The inclusion of IQC samples in the serological assays performed in the laboratory has highlighted batch to batch variation in commercial assays. The setting of acceptable limits for the IQC samples has increased confidence in the validity of assay results. PMID:7730475
Internal quality control: planning and implementation strategies.
Westgard, James O
2003-11-01
The first essential in setting up internal quality control (IQC) of a test procedure in the clinical laboratory is to select the proper IQC procedure to implement, i.e. choosing the statistical criteria or control rules, and the number of control measurements, according to the quality required for the test and the observed performance of the method. Then the right IQC procedure must be properly implemented. This review focuses on strategies for planning and implementing IQC procedures in order to improve the quality of the IQC. A quantitative planning process is described that can be implemented with graphical tools such as power function or critical-error graphs and charts of operating specifications. Finally, a total QC strategy is formulated to minimize cost and maximize quality. A general strategy for IQC implementation is recommended that employs a three-stage design in which the first stage provides high error detection, the second stage low false rejection and the third stage prescribes the length of the analytical run, making use of an algorithm involving the average of normal patients' data.
Li, Jing-Jing; Gao, Qi; Liu, Zhi-Dong; Kang, Qiong-Hua; Hou, Yi-Jun; Zhang, Luo-Chuan; Hu, Xiao-Mei; Li, Jie; Zhang, Juan
2015-01-01
Internal quality control (IQC) is a critical component of laboratory quality management, and IQC products can determine the reliability of testing results. In China, given the fact that most blood transfusion compatibility laboratories do not employ IQC products or do so minimally, there is a lack of uniform and standardized IQC methods. To explore the reliability of IQC products and methods, we studied 697 results from IQC samples in our laboratory from 2012 to 2014. The results showed that the sensitivity and specificity of the IQCs in anti-B testing were 100% and 99.7%, respectively. The sensitivity and specificity of the IQCs in forward blood typing, anti-A testing, irregular antibody screening, and cross-matching were all 100%. The reliability analysis indicated that 97% of anti-B testing results were at a 99% confidence level, and 99.9% of forward blood typing, anti-A testing, irregular antibody screening, and cross-matching results were at a 99% confidence level. Therefore, our IQC products and methods are highly sensitive, specific, and reliable. Our study paves the way for the establishment of a uniform and standardized IQC method for pre-transfusion compatibility testing in China and other parts of the world. PMID:26488582
Internal quality control: best practice.
Kinns, Helen; Pitkin, Sarah; Housley, David; Freedman, Danielle B
2013-12-01
There is a wide variation in laboratory practice with regard to implementation and review of internal quality control (IQC). A poor approach can lead to a spectrum of scenarios from validation of incorrect patient results to over investigation of falsely rejected analytical runs. This article will provide a practical approach for the routine clinical biochemistry laboratory to introduce an efficient quality control system that will optimise error detection and reduce the rate of false rejection. Each stage of the IQC system is considered, from selection of IQC material to selection of IQC rules, and finally the appropriate action to follow when a rejection signal has been obtained. The main objective of IQC is to ensure day-to-day consistency of an analytical process and thus help to determine whether patient results are reliable enough to be released. The required quality and assay performance varies between analytes as does the definition of a clinically significant error. Unfortunately many laboratories currently decide what is clinically significant at the troubleshooting stage. Assay-specific IQC systems will reduce the number of inappropriate sample-run rejections compared with the blanket use of one IQC rule. In practice, only three or four different IQC rules are required for the whole of the routine biochemistry repertoire as assays are assigned into groups based on performance. The tools to categorise performance and assign IQC rules based on that performance are presented. Although significant investment of time and education is required prior to implementation, laboratories have shown that such systems achieve considerable reductions in cost and labour.
Hu, Li-Tao; Wang, Zhi-Guo
2014-01-01
Internal quality control (IQC) has a long and well-established role in clinical laboratories and the quality of laboratories has achieved great improvement in China. However, the practice of IQC varies significantly between institutions and many problems still exists. Consequently, the Chinese National Center for Clinical Laboratories has been undertaking monthly nation-wide surveys of current IQC practice of tests since 2010 to monitor laboratory quality. Thyroid disease related tests were chosen for this research. Different numbers of laboratories in China participating national external quality assessment (EQA) schemes of Total Thyroxine (TT4), Total Triiodothyronine (TT3), Free Thyroxine (FT4) and Free Triiodothyronine (FT3) tests, and Thyroid Stimulating Hormone (TSH) measurements, were required to report the IQC information though the national external quality assessment (EQA) network platform. Survey data showed significant variability in all aspects of IQC practice. More than half of the laboratories are using a single concentration level of IQC material and up to 28.6% of the laboratories only use 1(2s) or 1(3s) to monitor IQC results for FT3, TT3, FT4, TT4, and TSH. The medians of the average time intervals of two control tests for FT3, TT3, FT4, TT4, and TSH are 33.6, 35.4, 33.6, 35.4, and 33.6 hours, respectively, more or less 1.4 days. When quality specifications based on biological variation are applied to imprecision evaluation, only 46.3%, 52.1%, 31.3%, 12.8%, and 5.86% laboratories meet the minimum performance for FT3, TT3, FT4, and TT4, 24.5%, 23.6%, 12.8%, and 5.86% of the all meet the desirable performance, and 4.4%, 3.9%, 2.5% and 3.0% of the all meet the optimal performance. While it shows a higher percentage of acceptable laboratories (98.1%, 87.9% and 39.0% meeting the minimum, desirable and optimal performance, respectively) for TSH. Not-well-designed IQC practices may affect the effectiveness of laboratory IQC and, thus, the adequacy of a laboratory to monitor system performance. Consequently, IQC practice should be designed according to performance of measure method and instrument. Both clinical laboratories and the government should make efforts to improve quality of clinical testing to ensure the patients' safety.
McFarlane, A; Aslan, B; Raby, A; Moffat, K A; Selby, R; Padmore, R
2015-12-01
Internal quality control (IQC) procedures are crucial for ensuring accurate patient test results. The IQMH Centre for Proficiency Testing conducted a web-based survey to gather information on the current IQC practices in coagulation testing. A questionnaire was distributed to 174 Ontario laboratories licensed to perform prothrombin time (PT) and activated partial thromboplastin time (APTT). All laboratories reported using two levels of commercial QC (CQC); 12% incorporate pooled patient plasma into their IQC program; >68% run CQC at the beginning of each shift; 56% following maintenance, with reagent changes, during a shift, or with every repeat sample; 6% only run CQC at the beginning of the day and 25% when the instruments have been idle for a defined period of time. IQC run frequency was determined by manufacturer recommendations (71%) but also influenced by the stability of test (27%), clinical impact of an incorrect test result (25%), and sample's batch number (10%). IQC was monitored using preset limits based on standard deviation (66%), precision goals (46%), or allowable performance limits (36%). 95% use multirules. Failure actions include repeating the IQC (90%) and reporting patient results; if repeat passes, 42% perform repeat analysis of all patient samples from last acceptable IQC. Variability exists in coagulation IQC practices among Ontario clinical laboratories. The recommendations presented here would be useful in encouraging standardized IQC practices. © 2015 John Wiley & Sons Ltd.
Li, Tingting; Wang, Wei; Zhao, Haijian; He, Falin; Zhong, Kun; Yuan, Shuai; Wang, Zhiguo
2017-09-01
This study aimed to evaluate whether the quality performance of clinical laboratories in China has been greatly improved and whether Internal Quality Control (IQC) practice of HbA1c has also been changed since National Center for Clinical Laboratories (NCCL) of China organized laboratories to report IQC data for HbA1c in 2012. Internal Quality Control information of 306 External Quality Assessment (EQA) participant laboratories which kept reporting IQC data in February from 2012 to 2016 were collected by Web-based EQA system. Then percentages of laboratories meeting four different imprecision specifications for current coefficient of variations (CVs) of HbA1c measurements were calculated. Finally, we comprehensively analyzed analytical systems and IQC practice of HbA1c measurements. The current CVs of HbA1c tests have decreased significantly from 2012 to 2016. And percentages of laboratories meeting four imprecision specifications for CVs all showed the increasing tendency year by year. As for analytical system, 52.1% (159/306) laboratories changed their systems with the change in principle of assay. And many laboratories began to use cation exchange high-performance liquid chromatography (CE-HPLC) instead of Immunoturbidimetry, because CE-HPLC owed a lower intra-laboratory CVs. The data of IQC practice, such as IQC rules and frequency, also showed significant variability among years with overall tendency of meeting requirements. The imprecision performance of HbA1c tests has been improved in these 5 years with the change in IQC practice, but it is still disappointing in China. Therefore, laboratories should actively find existing problems and take action to promote performance of HbA1c measurements. © 2016 Wiley Periodicals, Inc.
Prüller, F; Rosskopf, K; Mangge, H; Mahla, E; von Lewinski, D; Weiss, E C; Riegler, A; Enko, D
2017-12-01
Essentials In platelet function testing, standardized internal controls (IQC) are not commercially provided. Platelet function testing was performed daily on aliquoted pooled platelet concentrates. Pooled platelet concentrates showed stability for control purposes from Monday to Friday. Pooled platelet concentrates provide the necessary steadiness to serve as IQC material. Background Standardized commercially available control material for internal quality control (IQC) of light transmission aggregometry (LTA) is still lacking. Moreover, the availability of normal blood donors to provide fresh platelets is difficult in small laboratories, where 'volunteers' may be in short supply. Objectives To evaluate the implementation of buffy-coat-derived pooled platelet concentrates (PCs) for IQC material for LTA. Methods We used buffy-coat-derived pooled PCs from the blood bank as IQC material for LTA. On each weekend one PC was prepared (> 200 mL) and aliquoted from the original storage bag on a daily basis in four baby bags (40-50 mL), which were delivered from Monday to Friday to our laboratory. The IQC measurements of at least 85 work-weeks (from Monday to Friday) were evaluated with this new IQC material. LTA was performed on a four-channel Chronolog 700 Aggregometer (Chronolog Corporation, Havertown, PA, USA) (agonists: collagen, adenosine diphosphate [ADP], arachidonic acid [AA] and thrombin receptor activator peptide-6 [TRAP-6]). Results The medians of platelet aggregation from IQC measurements with collagen, ADP and AA from Monday to Friday were 68.0-59.5, 3.0-2.0 and 51.0-50.0%, respectively, and the mean of platelet aggregation with TRAP-6 was 71.2-66.4%. Conclusions Buffy-coat-derived pooled PCs serve as a reliable and robust IQC material for LTA measurements and would be beneficial for the whole laboratory procedure and employees' safety. © 2017 International Society on Thrombosis and Haemostasis.
Status of internal quality control for thyroid hormones immunoassays from 2011 to 2016 in China.
Zhang, Shishi; Wang, Wei; Zhao, Haijian; He, Falin; Zhong, Kun; Yuan, Shuai; Wang, Zhiguo
2018-01-01
Internal quality control (IQC) plays a key role in the evaluation of precision performance in clinical laboratories. This report aims to present precision status of thyroid hormones immunoassays from 2011 to 2016 in China. Through Clinet-EQA reporting system, IQC information of Triiodothyronine and Thyroxine in the form of free and total (FT3, TT3, FT4, TT4), as well as Thyroid Stimulating Hormone (TSH) were collected from participant laboratories submitting IQC data in February, 2011-2016. For each analyte, current CVs were compared among different years and measurement systems. Percentages of laboratories meeting five allowable imprecision specifications (pass rates) were also calculated. Analysis of IQC practice was conducted to constitute a complete report. Current CVs were decreasing significantly but pass rates increasing only for FT3 during 6 years. FT3, TT3, FT4, and TT4 had the highest pass rates comparing with 1/3TEa imprecision specification but TSH had this comparing with minimum imprecision specification derived from biological variation. Constituent ratios of four mainstream measurement systems changed insignificantly. In 2016, precision performance of Abbott and Roche systems were better than Beckman and Siemens systems for all analytes except FT3 had Siemens also better than Beckman. Analysis of IQC practice demonstrated wide variation and great progress in aspects of IQC rules and control frequency. With change of IQC practice, only FT3 had precision performance improved in 6 years. However, precision status of five analytes in China was still unsatisfying. Ongoing investigation and improvement of IQC have yet to be achieved. © 2017 Wiley Periodicals, Inc.
National survey on internal quality control for tumour markers in clinical laboratories in China.
Wang, Wei; Zhong, Kun; Yuan, Shuai; He, Falin; Du, Yuxuan; Hu, Zhehui; Wang, Zhiguo
2018-06-15
This survey was initiated to obtain knowledge on the current situation of internal quality control (IQC) practice for tumour markers (TMs) in China. Additionally, we tried to acquire the most appropriate quality specifications. This survey was a current status survey. The IQC information had been collected via online questionnaires. All of 1821 clinical laboratories which participated in the 2016 TMs external quality assessment (EQA) programme had been enrolled. The imprecision evaluation criteria were the minimal, desirable, and optimal allowable imprecisions based on biological variations, and 1/3 total allowable error (TEa) and 1/4 TEa. A total of 1628 laboratories answered the questionnaires (89%). The coefficients of variation (CVs) of the IQC of participant laboratories varied greatly from 1% (5 th percentile) to 13% (95 th percentile). More than 82% (82 - 91%) of participant laboratories two types of CVs met 1/3 TEa except for CA 19-9. The percentiles of current CVs were smaller than cumulative CVs. A number of 1240 laboratories (76%) reported their principles and systems used. The electrochemiluminescence was the most used principle (45%) and had the smallest CVs. The performance of laboratories for TMs IQC has yet to be improved. On the basis of the obtained results, 1/3 TEa would be realistic and attainable quality specification for TMs IQC for clinical laboratories in China.
Kim, Sung-Su; Choi, Hyun-Jeung; Kim, Jin Ju; Kim, M Sun; Lee, In-Seon; Byun, Bohyun; Jia, Lina; Oh, Myung Ryurl; Moon, Youngho; Park, Sarah; Choi, Joon-Seok; Chae, Seoung Wan; Nam, Byung-Ho; Kim, Jin-Soo; Kim, Jihun; Min, Byung Soh; Lee, Jae Seok; Won, Jae-Kyung; Cho, Soo Youn; Choi, Yoon-La; Shin, Young Kee
2018-01-11
In clinical translational research and molecular in vitro diagnostics, a major challenge in the detection of genetic mutations is overcoming artefactual results caused by the low-quality of formalin-fixed paraffin-embedded tissue (FFPET)-derived DNA (FFPET-DNA). Here, we propose the use of an 'internal quality control (iQC) index' as a criterion for judging the minimum quality of DNA for PCR-based analyses. In a pre-clinical study comparing the results from droplet digital PCR-based EGFR mutation test (ddEGFR test) and qPCR-based EGFR mutation test (cobas EGFR test), iQC index ≥ 0.5 (iQC copies ≥ 500, using 3.3 ng of FFPET-DNA [1,000 genome equivalents]) was established, indicating that more than half of the input DNA was amplifiable. Using this criterion, we conducted a retrospective comparative clinical study of the ddEGFR and cobas EGFR tests for the detection of EGFR mutations in non-small cell lung cancer (NSCLC) FFPET-DNA samples. Compared with the cobas EGFR test, the ddEGFR test exhibited superior analytical performance and equivalent or higher clinical performance. Furthermore, iQC index is a reliable indicator of the quality of FFPET-DNA and could be used to prevent incorrect diagnoses arising from low-quality samples.
Giannoli, Jean-Marc; Szymanowicz, Anton
2011-01-01
We propose a set of recommendations and practices to optimize the use of quality control of medical biology examinations. The fundamentals are reviewed: definition of a series of analysis, IQC at one or more level, Westgard alert rules and rejection, practical remedial actions to take for the technician, corrective and preventive actions to be implemented by the biologist. We have also formalized three flowcharts to guide the technician in their daily practice to ensure analytical quality of investigations carried out. These decision trees are the result of the experience submitted by an accredited and professional laboratory attentive to the ongoing improvement of IQC. This article can provide useful assistance to biologists for accreditation but also aims to foster collaboration reliable medical biology laboratory at the appropriate management of patients.
Kumar, B Vinodh; Mohan, Thuthi
2018-01-01
Six Sigma is one of the most popular quality management system tools employed for process improvement. The Six Sigma methods are usually applied when the outcome of the process can be measured. This study was done to assess the performance of individual biochemical parameters on a Sigma Scale by calculating the sigma metrics for individual parameters and to follow the Westgard guidelines for appropriate Westgard rules and levels of internal quality control (IQC) that needs to be processed to improve target analyte performance based on the sigma metrics. This is a retrospective study, and data required for the study were extracted between July 2015 and June 2016 from a Secondary Care Government Hospital, Chennai. The data obtained for the study are IQC - coefficient of variation percentage and External Quality Assurance Scheme (EQAS) - Bias% for 16 biochemical parameters. For the level 1 IQC, four analytes (alkaline phosphatase, magnesium, triglyceride, and high-density lipoprotein-cholesterol) showed an ideal performance of ≥6 sigma level, five analytes (urea, total bilirubin, albumin, cholesterol, and potassium) showed an average performance of <3 sigma level and for level 2 IQCs, same four analytes of level 1 showed a performance of ≥6 sigma level, and four analytes (urea, albumin, cholesterol, and potassium) showed an average performance of <3 sigma level. For all analytes <6 sigma level, the quality goal index (QGI) was <0.8 indicating the area requiring improvement to be imprecision except cholesterol whose QGI >1.2 indicated inaccuracy. This study shows that sigma metrics is a good quality tool to assess the analytical performance of a clinical chemistry laboratory. Thus, sigma metric analysis provides a benchmark for the laboratory to design a protocol for IQC, address poor assay performance, and assess the efficiency of existing laboratory processes.
Kumar, B. Vinodh; Mohan, Thuthi
2018-01-01
OBJECTIVE: Six Sigma is one of the most popular quality management system tools employed for process improvement. The Six Sigma methods are usually applied when the outcome of the process can be measured. This study was done to assess the performance of individual biochemical parameters on a Sigma Scale by calculating the sigma metrics for individual parameters and to follow the Westgard guidelines for appropriate Westgard rules and levels of internal quality control (IQC) that needs to be processed to improve target analyte performance based on the sigma metrics. MATERIALS AND METHODS: This is a retrospective study, and data required for the study were extracted between July 2015 and June 2016 from a Secondary Care Government Hospital, Chennai. The data obtained for the study are IQC - coefficient of variation percentage and External Quality Assurance Scheme (EQAS) - Bias% for 16 biochemical parameters. RESULTS: For the level 1 IQC, four analytes (alkaline phosphatase, magnesium, triglyceride, and high-density lipoprotein-cholesterol) showed an ideal performance of ≥6 sigma level, five analytes (urea, total bilirubin, albumin, cholesterol, and potassium) showed an average performance of <3 sigma level and for level 2 IQCs, same four analytes of level 1 showed a performance of ≥6 sigma level, and four analytes (urea, albumin, cholesterol, and potassium) showed an average performance of <3 sigma level. For all analytes <6 sigma level, the quality goal index (QGI) was <0.8 indicating the area requiring improvement to be imprecision except cholesterol whose QGI >1.2 indicated inaccuracy. CONCLUSION: This study shows that sigma metrics is a good quality tool to assess the analytical performance of a clinical chemistry laboratory. Thus, sigma metric analysis provides a benchmark for the laboratory to design a protocol for IQC, address poor assay performance, and assess the efficiency of existing laboratory processes. PMID:29692587
Zeng, Rong; Wang, Wei; Zhao, Haijian; Fei, Yang; Wang, Zhiguo
2015-01-01
The narrow gap of HbA1 value of mass fraction between "normal" (< 6.0%) and "diabetes" (≥ 6.5%) necessitates tight control of inter-assay standardization, assay precision, and trueness. This survey was initiated to obtain knowledge of the current situation of internal quality control (IQC) practice for HbA(1c) in China and find out the most appropriate quality specifications. Data of IQC for HbA(1c) in 331 institutions participating in the national proficiency testing (PT) programs in China were evaluated using four levels of quality specifications, and the percentages of laboratories meeting the quality requirement were calculated to find out the most appropriate quality specifications for control materials of HbA(1c) in China. The IQC data varied vastly among 331 clinical laboratories in China. The measurement of control materials covered a wide range from 4.52% to 12.24% (inter-quartile range) and there were significant differences among the CVs of different methods, including LPLC, CE-HPLC, AC-HPLC, immunoturbidimetry, and others. Among the four main methods, CE-HPLC and AC-HPLC achieved a better precision. As we can see, the performance of laboratories for HbA(1c) has yet to be improved. Clinical laboratories in China should improve their performance with a stricter imprecision criteria.
Li, Tingting; Wang, Wei; Zhao, Haijian; He, Falin; Zhong, Kun; Yuan, Shuai; Wang, Zhiguo
2017-09-07
This study aimed to investigate the status of internal quality control (IQC) for cardiac biomarkers from 2011 to 2016 so that we can have overall knowledge of the precision level of measurements in China and set appropriate precision specifications. Internal quality control data of cardiac biomarkers, including creatinine kinase MB (CK-MB) (μg/L), CK-MB(U/L), myoglobin (Mb), cardiac troponin I (cTnI), cardiac troponin T (cTnT), and homocysteines (HCY), were collected by a web-based external quality assessment (EQA) system. Percentages of laboratories meeting five precision quality specifications for current coefficient of variations (CVs) were calculated. Then, appropriate precision specifications were chosen for these six analytes. Finally, the CVs and IQC practice were further analyzed with different grouping methods. The current CVs remained nearly constant for 6 years. cTnT had the highest pass rates every year against five specifications, whereas HCY had the lowest pass rates. Overall, most analytes had a satisfactory performance (pass rates >80%), except for HCY, if one-third TEa or the minimum specification were employed. When the optimal specification was applied, the performance of most analytes was frustrating (pass rates < 60%) except for cTnT. The appropriate precision specifications of Mb, cTnI, cTnT and HCY were set as current CVs less than 9.20%, 9.90%, 7.50%, 10.54%, 7.63%, and 6.67%, respectively. The data of IQC practices indicated wide variation and substantial progress. The precision performance of cTnT was already satisfying, while the other five analytes, especially HCY, were still frustrating; thus, ongoing investigation and continuous improvement for IQC are still needed. © 2017 Wiley Periodicals, Inc.
Duan, Min; Wang, Wei; Zhao, Haijian; Zhang, Chuanbao; He, Falin; Zhong, Kun; Yuan, Shuai; Wang, Zhiguo
2018-05-01
Internal quality control (IQC) is essential for precision evaluation and continuous quality improvement. This study aims to investigate the IQC status of blood gas analysis (BGA) in clinical laboratories of China from 2014 to 2017. IQC information on BGA (including pH, pCO2, pO2, Na+, K+, Ca2+, Cl-) was submitted by external quality assessment (EQA) participant laboratories and collected through Clinet-EQA reporting system in March from 2014 to 2017. First, current CVs were compared among different years and measurement systems. Then, percentages of laboratories meeting five allowable imprecision specifications for each analyte were calculated, respectively. Finally, laboratories were divided into different groups based on control rules and frequency to compare their variation trend. The current CVs of BGA were significantly decreasing from 2014 to 2017. pH and pCO2 got the highest pass rates when compared with the minimum imprecision specification, whereas pO2, Na+, K+, Ca2+, Cl- got the highest pass rates when 1/3 TEa imprecision specification applied. The pass rates of pH, pO2, Na+, K+, Ca2+, Cl- were significantly increasing during the 4 years. The comparisons of current CVs among different measurement systems showed that the precision performance of different analytes among different measurement systems had no regular distribution from 2014 to 2017. The analysis of IQC practice indicated great progress and improvement among different years. The imprecision performance of BGA has improved from 2014 to 2017, but the status of imprecision performance in China remains unsatisfying. Therefore, further investigation and continuous improvement measures should be taken.
Sultan, Sadia; Zaheer, Hasan Abbas; Waheed, Usman; Baig, Mohammad Amjad; Rehan, Asma; Irfan, Syed Mohammed
2018-01-01
Internal quality control (IQC) is the backbone of quality assurance program. In blood banking, the quality control of blood products ensures the timely availability of a blood component of high quality with maximum efficacy and minimal risk to potential recipients. The main objective of this study is to analyze the IQC of blood products as an indicator of our blood bank performance. An observational cross-sectional study was conducted at the blood bank of Liaquat National Hospital and Medical College, from January 2014 to December 2015. A total of 100 units of each blood components were arbitrarily chosen during the study. Packed red cell units were evaluated for hematocrit (HCT); random platelet concentrates were evaluated for pH, yield, and culture; fresh frozen plasma (FFP) and cryoprecipitate (CP) were evaluated for unit volume, factor VIII, and fibrinogen concentrations. A total of 400 units were tested for IQC. The mean HCT of packed red cells was 69.5 ± 7.24, and in 98% units, it met the standard (<80% of HCT). The mean platelet yield was 8.8 ± 3.40 × 10 9 /L and pH was ≥6.2 in 98% bags; cultures were negative in 97% of units tested. Mean factor VIII and fibrinogen levels were found to be 84.24 ± 15.01 and 247.17 ± 49.69 for FFP, respectively. For CP, mean factor VIII and fibrinogen level were found to be 178.75 ± 86.30 and 420.7 ± 75.32, respectively. The IQC of blood products at our blood bank is in overall compliance and met recommended international standards. Implementation of standard operating procedures, accomplishment of standard guidelines, proper documentation with regular audit, and staff competencies can improve the quality performance of the transfusion services.
Tavares, Suelene B N; Alves de Sousa, Nadja L; Manrique, Edna J C; Pinheiro de Albuquerque, Zair B; Zeferino, Luiz C; Amaral, Rita G
2008-06-25
Rapid prescreening (RPS) is an internal quality-control (IQC) method that is used both to reduce errors in the laboratory and to measure the sensitivity of routine screening (RS). Little direct comparison data are available comparing RPS with other more widely used IQC methods. The authors compared the performance of RPS, 10% random review of negative smears (R-10%), and directed rescreening of negative smears based on clinical risk criteria (RCRC) over 1 year in a community clinic setting. In total, 6,135 smears were evaluated. The sensitivity of RS alone was 71.3%. RPS detected significantly more (132 cases) false-negative (FN) cases than either R-10% (7 cases) or RCRC (32 cases). RPS significantly improved the overall sensitivity of the laboratory (71.3-92.2%; P = .001); neither R-10% nor RCRC significantly changed the sensitivity of RS. RPS was not as specific as the other methods, although nearly 68% of all abnormalities detected by RPS were verified as real. RPS of 100% of smears required the same amount of time as RCRC but required twice as much time as R-10%. The current results demonstrated that RPS is a much more effective IQC method than either R-10% or RCRC. RPS detects significantly more errors and can improve the overall sensitivity of a laboratory with either a modest increase or no increase in overall time spent on IQC. R-10% is an insensitive IQC method, and neither R-10% nor RCRC can significantly improve the overall sensitivity of a laboratory. (c) 2008 American Cancer Society.
A Merged IQC/SOS Theory for Analysis and Synthesis of Nonlinear Control Systems
2015-06-23
constraints. As mentioned previously, this enables new applications of IQCs to analyze the robustness of time-varying and nonlinear systems . This...enables new applications of IQCs to analyze the robustness of time-varying and nonlinear systems . This section considers the analysis of nonlinear systems ...AFRL-AFOSR-VA-TR-2016-0008 A Merged IQC/SOS Theory for Analysis and Synthesis of Nonlinear Control Systems Gary Balas REGENTS OF THE UNIVERSITY OF
ESIP Information Quality Cluster (IQC)
NASA Technical Reports Server (NTRS)
Ramapriyan, H. K.; Peng, Ge; Moroni, David F.
2016-01-01
The Information Quality Cluster (IQC) within the Federation of Earth Science Information Partners (ESIP) was initially formed in 2011 and has evolved significantly over time. The current objectives of the IQC are to: 1. Actively evaluate community data quality best practices and standards; 2. Improve capture, description, discovery, and usability of information about data quality in Earth science data products; 3. Ensure producers of data products are aware of standards and best practices for conveying data quality, and data providers distributors intermediaries establish, improve and evolve mechanisms to assist users in discovering and understanding data quality information; and 4. Consistently provide guidance to data managers and stewards on how best to implement data quality standards and best practices to ensure and improve maturity of their data products. The activities of the IQC include: 1. Identification of additional needs for consistently capturing, describing, and conveying quality information through use case studies with broad and diverse applications; 2. Establishing and providing community-wide guidance on roles and responsibilities of key players and stakeholders including users and management; 3. Prototyping of conveying quality information to users in a more consistent, transparent, and digestible manner; 4. Establishing a baseline of standards and best practices for data quality; 5. Evaluating recommendations from NASA's DQWG in a broader context and proposing possible implementations; and 6. Engaging data providers, data managers, and data user communities as resources to improve our standards and best practices. Following the principles of openness of the ESIP Federation, IQC invites all individuals interested in improving capture, description, discovery, and usability of information about data quality in Earth science data products to participate in its activities.
Yu, Yang; Ma, Chunya; Feng, Qian; Chen, Xin; Guan, Xiaozhen; Zhang, Xiaojuan; Chen, Linfeng; Lin, Zilin; Pan, Jichun; Zhang, Ting; Luo, Qun; Wang, Deqing
2013-05-01
The aim of this study was to establish and to optimize the preparation technology of whole blood internal quality control (IQC) products for blood transfusion compatibility testing. Several B-type RhD-negative blood samples collected from healthy donors were mixed. Two groups of whole blood IQC products, namely, the preservative solution group (PS group) and the saline group, were prepared. The agglutination intensity of IQC sample red cells and anti-B antibody, IgM anti-A antibody and reverse-typing A cell, IgG anti-D and O-type RhD-positive red cells, as well as free hemoglobin concentration in the supernatant of the two groups were detected. The erythrocytes in both groups were damaged to a certain extent during storage, but no evident (above moderate) hemolysis was observed in the stored sample within 42 days. The red cells remained structurally complete and the reaction activity of IgG anti-D reagent remained generally unchanged (P>0.05). Although the reaction activity oscillation of IgM anti-A reagent was observed, the agglutination intensity varied within an acceptable range of 1+. No difference was observed between the preparation methods of the samples, i.e., between the erythrocyte washed with saline and the one washed with red cell preservative solution (P>0.05). The long shelf life, low variance between tubes and stable antigen-antibody reaction activity of the whole blood IQC products prepared using the proposed method can meet the requirements of blood transfusion compatibility testing.
Consensus for multi-agent systems with time-varying input delays
NASA Astrophysics Data System (ADS)
Yuan, Chengzhi; Wu, Fen
2017-10-01
This paper addresses the consensus control problem for linear multi-agent systems subject to uniform time-varying input delays and external disturbance. A novel state-feedback consensus protocol is proposed under the integral quadratic constraint (IQC) framework, which utilises not only the relative state information from neighbouring agents but also the real-time information of delays by means of the dynamic IQC system states for feedback control. Based on this new consensus protocol, the associated IQC-based control synthesis conditions are established and fully characterised as linear matrix inequalities (LMIs), such that the consensus control solution with optimal ? disturbance attenuation performance can be synthesised efficiently via convex optimisation. A numerical example is used to demonstrate the proposed approach.
Information Quality as a Foundation for User Trustworthiness of Earth Science Data.
NASA Astrophysics Data System (ADS)
Wei, Y.; Moroni, D. F.; Ramapriyan, H.; Peng, G.
2017-12-01
Information quality is multidimensional. Four different aspects of information quality can be defined based on the lifecycle stages of Earth Science data products: science, product, stewardship and services. With increasing requirements on ensuring and improving information quality coming from multiple government agencies and throughout industry, there have been considerable efforts toward improving information quality during the last decade, much of which has not been well vetted in a collective sense until recently. Given this rich background of prior work, the Information Quality Cluster (IQC), established within the Federation of Earth Science Information Partners (ESIP) in 2011, and reactivated in the summer of 2014, has been active with membership from multiple organizations. The IQC's objectives and activities, aimed at ensuring and improving information quality for Earth science data and products, are also considered vital toward improving the trustworthiness of Earth science data to a vast and interdisciplinary community of data users. During 2016, several members of the IQC have led the development and assessment of four use cases. This was followed up in 2017 with multiple panel sessions at the 2017 Winter and Summer ESIP Meetings to survey the challenges posed in the various aspects of information quality. What was discovered to be most lacking is the transparency of data lineage (i.e., provenance and maturity), uniform methods for uncertainty characterization, and uniform quality assurance data and metadata. While solutions to these types of issues exist, most data producers have little time to investigate and collaborate to arrive at and conform to a consensus approach. The IQC has positioned itself as a community platform to bring together all relevant stakeholders from data producers, repositories, program managers, and the end users. A combination of both well-vetted and "trailblazing" solutions are presented to address how data trustworthiness can be elevated and maintained through optimized extraction, curation, and dissemination of information quality artifacts.
Ye, Yuanyuan; Wang, Wei; Zhao, Haijian; He, Falin; Zhong, Kun; Yuan, Shuai; Wang, Zhiguo
2017-09-01
To investigate the situation of Internal Quality Control (IQC) practice for total cholesterol, triglycerides, HDL-cholesterol and LDL-cholesterol from 2014 to 2016 in laboratories in China and provide improvement measurements. A web-based External Quality Assessment (EQA) system was used to collect IQC data of lipid parameters in laboratories which continuously participated in the national EQA programs in China from 2014 to 2016. Pass rate of the coefficients of variation (CVs) of two level quality controls in four lipid parameters were calculated according to six quality specifications for precision to evaluate the current status of precision level of the four lipid parameters and their change over time in China. 533, 512, 504, and 466 laboratories continuously reported the data of level one for total cholesterol, triglyceride, HDL-cholesterol and LDL-cholesterol, and 212, 210, 208 and 198 laboratories reported the level two, respectively. The percentage of laboratories meeting the quality specification varied based on different criteria. Non-significant change can be found in the pass rate of CVs over time. The number of laboratories using a closed system increased over time, but still only accounted for a small proportion. There is no significant difference in the pass rate of CVs between closed and open systems. Triglycerides currently have a fairly good performance in China. While the performance of laboratories on total cholesterol, HDL-cholesterol and LDL-cholesterol has yet to be improved.
Li, Jin-ming; Zheng, Huai-jing; Wang, Lu-nan; Deng, Wei
2003-04-01
To establish a model for one choosing controls with a suitable concentration for internal quality control (IQC) with qualitative ELISA detection, and a consecutive plotting method on Levey-Jennings control chart when reagent kit lot is changed. First, a series of control serum with 0.2, 0.5, 1.0, 2.0 and 5.0ng/ml HBsAg respectively were assessed for within-run and between-run precision according to NCCLs EP5 document. Then, a linear regression equation (y=bx + a) with best correlation coefficient (r > 0.99) was established based on S/CO values of the series of control serum. Finally, one could choose controls with S/CO value calculated from the equation (y = bx + a) minus the product of the S/CO value multiplying three-fold between-run CV to be still more than 1.0 for IQC use. For consecutive plotting on Levey-Jennings control chart when ELISA kit lot was changed, the new lot kits were used to detect the same series of HBsAg control serum as above. Then, a new linear regression equation (y2 = b2x2 + a2) with best correlation coefficient was obtained. The old one (y1 =b1x1 + a1) could be obtained based on the mean values from above precision assessment. The S/CO value of a control serum detected by new lot kit could be changed to that detected by old kit lot based on the factor of y2/y1. Therefore, the plotting on primary Levey-Jennings control chart could be continued. The within-run coefficient of variation CV of the ELISA method for control serum with 0.2, 0.5, 1.0, 2.0 and 5.0ng/ml HBsAg were 11.08%, 9.49%, 9.83%, 9.18% and 7.25%, respectively, and between-run CV were 13.25%, 14.03%, 15.11%, 13.29% and 9.92%. The linear regression equation with best correlation coefficient from a test at random was y = 3.509x + 0.180. The suitable concentration of control serum for IQC could be 0.5ng/ml or 1.0ng/ml. The linear regression equation from the old lot and other two new lots of the ELISA kits were y1 = 3.550(x1) + 0.226, y2 = 3.238(x2) +0.388, and y3 =3.428(x3) + 0.148, respectively. Then, the transferring factors of 0.960 (y2/y1) and 0.908 (y3/y1) were obtained. The results shows that the model established for IQC control serum concentration selecting and for consecutive plotting on control chart when the reagent lot is changed is effective and practical.
Jassam, Nuthar; Yundt-Pacheco, John; Jansen, Rob; Thomas, Annette; Barth, Julian H
2013-08-01
The implementation of national and international guidelines is beginning to standardise clinical practice. However, since many guidelines have decision limits based on laboratory tests, there is an urgent need to ensure that different laboratories obtain the same analytical result on any sample. A scientifically-based quality control process will be a pre-requisite to provide this level of analytical performance which will support evidence-based guidelines and movement of patients across boundaries while maintaining standardised outcomes. We discuss the finding of a pilot study performed to assess UK clinical laboratories readiness to work to a higher grade quality specifications such as biological variation-based quality specifications. Internal quality control (IQC) data for HbA1c, glucose, creatinine, cholesterol and high density lipoprotein (HDL)-cholesterol were collected from UK laboratories participating in the Bio-Rad Unity QC programme. The median of the coefficient of variation (CV%) of the participating laboratories was evaluated against the CV% based on biological variation. Except creatinine, the other four analytes had a variable degree of compliance with the biological variation-based quality specifications. More than 75% of the laboratories met the biological variation-based quality specifications for glucose, cholesterol and HDL-cholesterol. Slightly over 50% of the laboratories met the analytical goal for HBA1c. Only one analyte (cholesterol) had a performance achieving the higher quality specifications consistent with 5σ. Our data from IQC do not consistently demonstrate that the results from clinical laboratories meet evidence-based quality specifications. Therefore, we propose that a graded scale of quality specifications may be needed at this stage.
Franco, José G; Petersen, Claudia G; Mauri, Ana L; Vagnini, Laura D; Renzi, Adriana; Petersen, Bruna; Mattila, M C; Comar, Vanessa A; Ricci, Juliana; Dieamant, Felipe; Oliveira, João Batista A; Baruffi, Ricardo L R
2017-06-01
KPIs have been employed for internal quality control (IQC) in ART. However, clinical KPIs (C-KPIs) such as age, AMH and number of oocytes collected are never added to laboratory KPIs (L-KPIs), such as fertilization rate and morphological quality of the embryos for analysis, even though the final endpoint is the evaluation of clinical pregnancy rates. This paper analyzed if a KPIs-score strategy with clinical and laboratorial parameters could be used to establish benchmarks for IQC in ART cycles. In this prospective cohort study, 280 patients (36.4±4.3years) underwent ART. The total KPIs-score was obtained by the analysis of age, AMH (AMH Gen II ELISA/pre-mixing modified, Beckman Coulter Inc.), number of metaphase-II oocytes, fertilization rates and morphological quality of the embryonic lot. The total KPIs-score (C-KPIs+L-KPIs) was correlated with the presence or absence of clinical pregnancy. The relationship between the C-KPIs and L-KPIs scores was analyzed to establish quality standards, to increase the performance of clinical and laboratorial processes in ART. The logistic regression model (LRM), with respect to pregnancy and total KPIs-score (280 patients/102 clinical pregnancies), yielded an odds ratio of 1.24 (95%CI = 1.16-1.32). There was also a significant difference (p<0.0001) with respect to the total KPIs-score mean value between the group of patients with clinical pregnancies (total KPIs-score=20.4±3.7) and the group without clinical pregnancies (total KPIs-score=15.9±5). Clinical pregnancy probabilities (CPP) can be obtained using the LRM (prediction key) with the total KPIs-score as a predictor variable. The mean C-KPIs and L-KPIs scores obtained in the pregnancy group were 11.9±2.9 and 8.5±1.7, respectively. Routinely, in all cases where the C-KPIs score was ≥9, after the procedure, the L-KPIs score obtained was ≤6, a revision of the laboratory procedure was performed to assess quality standards. This total KPIs-score could set up benchmarks for clinical pregnancy. Moreover, IQC can use C-KPIs and L-KPIs scores to detect problems in the clinical-laboratorial interface.
Padoan, Andrea; Antonelli, Giorgia; Aita, Ada; Sciacovelli, Laura; Plebani, Mario
2017-10-26
The present study was prompted by the ISO 15189 requirements that medical laboratories should estimate measurement uncertainty (MU). The method used to estimate MU included the: a) identification of quantitative tests, b) classification of tests in relation to their clinical purpose, and c) identification of criteria to estimate the different MU components. Imprecision was estimated using long-term internal quality control (IQC) results of the year 2016, while external quality assessment schemes (EQAs) results obtained in the period 2015-2016 were used to estimate bias and bias uncertainty. A total of 263 measurement procedures (MPs) were analyzed. On the basis of test purpose, in 51 MPs imprecision only was used to estimate MU; in the remaining MPs, the bias component was not estimable for 22 MPs because EQAs results did not provide reliable statistics. For a total of 28 MPs, two or more MU values were calculated on the basis of analyte concentration levels. Overall, results showed that uncertainty of bias is a minor factor contributing to MU, the bias component being the most relevant contributor to all the studied sample matrices. The model chosen for MU estimation allowed us to derive a standardized approach for bias calculation, with respect to the fitness-for-purpose of test results. Measurement uncertainty estimation could readily be implemented in medical laboratories as a useful tool in monitoring the analytical quality of test results since they are calculated using a combination of both the long-term imprecision IQC results and bias, on the basis of EQAs results.
Koerbin, Gus; Liu, Jiakai; Eigenstetter, Alex; Tan, Chin Hon; Badrick, Tony; Loh, Tze Ping
2018-02-15
A product recall was issued for the Roche/Hitachi Cobas Gentamicin II assays on 25 th May 2016 in Australia, after a 15 - 20% positive analytical shift was discovered. Laboratories were advised to employ the Thermo Fisher Gentamicin assay as an alternative. Following the reintroduction of the revised assay on 12 th September 2016, a second reagent recall was made on 20 th March 2017 after the discovery of a 20% negative analytical shift due to erroneous instrument adjustment factor. The practices of an index laboratory were examined to determine how the analytical shifts evaded detection by routine internal quality control (IQC) and external quality assurance (EQA) systems. The ability of the patient result-based approaches, including moving average (MovAvg) and moving sum of outliers (MovSO) approaches in detecting these shifts were examined. Internal quality control data of the index laboratory were acceptable prior to the product recall. The practice of adjusting IQC target following a change in assay method resulted in the missed negative shift when the revised Roche assay was reintroduced. While the EQA data of the Roche subgroup showed clear negative bias relative to other laboratory methods, the results were considered as possible 'matrix effect'. The MovAvg method detected the positive shift before the product recall. The MovSO did not detect the negative shift in the index laboratory but did so in another laboratory 5 days before the second product recall. There are gaps in current laboratory quality practices that leave room for analytical errors to evade detection.
NASA Astrophysics Data System (ADS)
Liu, Yu-Hui; Wang, Shi-Ming; Wang, Chen-Wen; Zhu, Chaoyuan; Han, Ke-Li; Lin, Sheng-Hsien
2016-10-01
The excited-state orientation hydrogen-bonding dynamics, and vibronic spectra of isoquinoline (IQ) and its cationic form IQc in water have been investigated at the time-dependent density functional theory quantum chemistry level plus Franck-Condon simulation and interpretation. The excited-state orientation hydrogen bond strengthening has been found in IQ:H2O complex due to the charge redistribution upon excitation; this is interpreted by simulated 1:1 mixed absorption spectra of free IQ and IQ:H2O complex having best agreement with experimental results. Conversely, the orientation hydrogen bond in IQc:H2O complex would be strongly weakening in the S1 state and this is interpreted by simulated absorption spectra of free IQc having best agreement with experimental results. By performing Franck-Condon simulation, it reveals that several important vibrational normal modes with frequencies about 1250 cm-1 involving the wagging motion of the hydrogen atoms are very sensitive to the formation of the orientation hydrogen bond for the IQ/IQc:H2O complex and this is confirmed by damped Franck-Condon simulation with free IQ/IQc in water. However, the emission spectra of the IQ and IQc in water have been found differently. Upon the excitation, the simulated fluorescence of IQ in water is dominated by the IQ:H2O complex; thus hydrogen bond between IQ and H2O is much easier to form in the S1 state. While the weakened hydrogen bond in IQc:H2O complex is probably cleaved upon the laser pulse because the simulated emission spectrum of the free IQc is in better agreement with the experimental results.
Cui, Ming; Xu, Lili; Wang, Huimin; Ju, Shaoqing; Xu, Shuizhu; Jing, Rongrong
2017-12-01
Measurement uncertainty (MU) is a metrological concept, which can be used for objectively estimating the quality of test results in medical laboratories. The Nordtest guide recommends an approach that uses both internal quality control (IQC) and external quality assessment (EQA) data to evaluate the MU. Bootstrap resampling is employed to simulate the unknown distribution based on the mathematical statistics method using an existing small sample of data, where the aim is to transform the small sample into a large sample. However, there have been no reports of the utilization of this method in medical laboratories. Thus, this study applied the Nordtest guide approach based on bootstrap resampling for estimating the MU. We estimated the MU for the white blood cell (WBC) count, red blood cell (RBC) count, hemoglobin (Hb), and platelets (Plt). First, we used 6months of IQC data and 12months of EQA data to calculate the MU according to the Nordtest method. Second, we combined the Nordtest method and bootstrap resampling with the quality control data and calculated the MU using MATLAB software. We then compared the MU results obtained using the two approaches. The expanded uncertainty results determined for WBC, RBC, Hb, and Plt using the bootstrap resampling method were 4.39%, 2.43%, 3.04%, and 5.92%, respectively, and 4.38%, 2.42%, 3.02%, and 6.00% with the existing quality control data (U [k=2]). For WBC, RBC, Hb, and Plt, the differences between the results obtained using the two methods were lower than 1.33%. The expanded uncertainty values were all less than the target uncertainties. The bootstrap resampling method allows the statistical analysis of the MU. Combining the Nordtest method and bootstrap resampling is considered a suitable alternative method for estimating the MU. Copyright © 2017 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.
Badrick, Tony; Graham, Peter
2018-03-28
Internal Quality Control and External Quality Assurance are separate but related processes that have developed independently in laboratory medicine over many years. They have different sample frequencies, statistical interpretations and immediacy. Both processes have evolved absorbing new understandings of the concept of laboratory error, sample material matrix and assay capability. However, we do not believe at the coalface that either process has led to much improvement in patient outcomes recently. It is the increasing reliability and automation of analytical platforms along with improved stability of reagents that has reduced systematic and random error, which in turn has minimised the risk of running less frequent IQC. We suggest that it is time to rethink the role of both these processes and unite them into a single approach using an Average of Normals model supported by more frequent External Quality Assurance samples. This new paradigm may lead to less confusion for laboratory staff and quicker responses to and identification of out of control situations.
Queiroz Filho, José; de Oliveira Crispim Freitas, Janaina Cristiana; Caldas Pessoa, Daliana; Eleutério Júnior, José; Giraldo, Paulo César; Gonçalves, Ana Katherine
2017-01-01
The aim of this study was to evaluate the 100% rapid review (100%-RR) as an effective tool for internal quality control (IQC) in gynecological cytopathology services. A total of 8,677 swabs were analyzed; the negative results were submitted to 100%-RR. Divergent cases were discussed in a consensus meeting to reach a conclusion on the final diagnosis. The data were entered into SAS statistical software, and the agreement of the 100%-RR results with the final diagnosis was tested with the weighted kappa statistic. Of the 8,155 smears characterized as negative, 255 (3.13%) were abnormal smears, and 552 (6.77%) unsatisfactory smears were deemed negative. Regarding the results on the 8,155 smears subjected to 100%-RR when compared with the final diagnosis, there was agreement in 7,063 (86.60%) of them, and there were 1,092 (13.40%) discordant results (65.6%, unsatisfactory; 5.47%, atypical squamous cells of undetermined significance [ASC-US]). The κ index had an agreement of 0.867, with κ = 0.734 (p < 0.0001). Compared with the final diagnosis, the sensitivity of 100%-RR was 99.91% and its specificity was 99.4% for severe abnormalities. The sensitivity for high-grade squamous intraepithelial lesions was 88.2%, with a specificity of 100.00%. For abnormalities considered borderline, such as ASC-US, the sensitivity was 94.50% and the specificity was 99.5%. The 100%-RR was considered efficient when used as an IQC method. © 2017 S. Karger AG, Basel.
Grosset, Andrée-Anne; Loayza-Vega, Kevin; Adam-Granger, Éloïse; Birlea, Mirela; Gilks, Blake; Nguyen, Bich; Soucy, Geneviève; Tran-Thanh, Danh; Albadine, Roula; Trudel, Dominique
2017-12-21
Hematoxylin and eosin (H&E) staining is a well-established technique in histopathology. However, immunohistochemistry (IHC) interpretation is done exclusively with hematoxylin counterstaining. Our goal was to investigate the potential of H&E as counterstaining (H&E-IHC) to allow for visualization of a marker while confirming the diagnosis on the same slide. The quality of immunostaining and the fast-technical performance were the main criteria to select the final protocol. We stained multiple diagnostic tissues with class I IHC tests with different subcellular localization markers (anti-CK7, CK20, synaptophysin, CD20, HMB45, and Ki-67) and with double-staining on prostate tissues with anti-high molecular weight keratins/p63 (DAB detection) and p504s (alkaline phosphatase detection). To validate the efficacy of the counterstaining, we stained tissue microarrays from the Canadian Immunohistochemistry Quality Control (cIQc) with class II IHC tests (ER, PR, HER2, and p53 markers). Interobserver and intraobserver concordance was assessed by κ statistics. Excellent agreement of H&E-IHC interpretation was observed in comparison with standard IHC from our laboratory (κ, 0.87 to 1.00), and with the cIQc reference values (κ, 0.81 to 1.00). Interobserver and intraobserver agreement was excellent (κ, 0.89 to 1.00 and 0.87 to 1.00, respectively). We therefore show for the first time the potential of using H&E counterstaining for IHC interpretation. We recommend the H&E-IHC protocol to enhance diagnostic precision for the clinical workflow and research studies.
Ayling, Pete; Hill, Robert; Jassam, Nuthar; Kallner, Anders; Khatami, Zahra
2017-11-01
Background A logical consequence of the introduction of robotics and high-capacity analysers has seen a consolidation to larger units. This requires new structures and quality systems to ensure that laboratories deliver consistent and comparable results. Methods A spreadsheet program was designed to accommodate results from up to 12 different instruments/laboratories and present IQC data, i.e. Levey-Jennings and Youden plots and comprehensive numerical tables of the performance of each item. Input of data was made possible by a 'data loader' by which IQC data from the individual instruments could be transferred to the spreadsheet program on line. Results A set of real data from laboratories is used to populate the data loader and the networking software program. Examples are present from the analysis of variance components, the Levey-Jennings and Youden plots. Conclusions This report presents a software package that allows the simultaneous management and detailed monitoring of the performance of up to 12 different instruments/laboratories in a fully interactive mode. The system allows a quality manager of networked laboratories to have a continuous updated overview of the performance. This software package has been made available at the ACB website.
Interest and limits of the six sigma methodology in medical laboratory.
Scherrer, Florian; Bouilloux, Jean-Pierre; Calendini, Ors'Anton; Chamard, Didier; Cornu, François
2017-02-01
The mandatory accreditation of clinical laboratories in France provides an incentive to develop real tools to measure performance management methods and to optimize the management of internal quality controls. Six sigma methodology is an approach commonly applied to software quality management and discussed in numerous publications. This paper discusses the primary factors that influence the sigma index (the choice of the total allowable error, the approach used to address bias) and compares the performance of different analyzers on the basis of the sigma index. Six sigma strategy can be applied to the policy management of internal quality control in a laboratory and demonstrates through a comparison of four analyzers that there is no single superior analyzer in clinical chemistry. Similar sigma results are obtained using approaches toward bias based on the EQAS or the IQC. The main difficulty in using the six sigma methodology lies in the absence of official guidelines for the definition of the total error acceptable. Despite this drawback, our comparison study suggests that difficulties with defined analytes do not vary with the analyzer used.
NASA Technical Reports Server (NTRS)
Ramapriyan, H. K. (Rama); Peng, Ge; Moroni, David; Shie, Chung-Lin
2016-01-01
Quality of products is always of concern to users regardless of the type of products. The focus of this paper is on the quality of Earth science data products. There are four different aspects of quality scientific, product, stewardship and service. All these aspects taken together constitute Information Quality. With increasing requirement on ensuring and improving information quality, there has been considerable work related to information quality during the last several years. Given this rich background of prior work, the Information Quality Cluster (IQC), established within the Federation of Earth Science Information Partners (ESIP) has been active with membership from multiple organizations. Its objectives and activities, aimed at ensuring and improving information quality for Earth science data and products, are discussed briefly.
NASA Technical Reports Server (NTRS)
Ramapriyan, Hampapuram; Peng, Ge; Moroni, David; Shie, Chung-Lin
2016-01-01
Quality of products is always of concern to users regardless of the type of products. The focus of this paper is on the quality of Earth science data products. There are four different aspects of quality - scientific, product, stewardship and service. All these aspects taken together constitute Information Quality. With increasing requirement on ensuring and improving information quality, there has been considerable work related to information quality during the last several years. Given this rich background of prior work, the Information Quality Cluster (IQC), established within the Federation of Earth Science Information Partners (ESIP) has been active with membership from multiple organizations. Its objectives and activities, aimed at ensuring and improving information quality for Earth science data and products, are discussed briefly.
Vidal, J L Martínez; Vega, A Belmonte; López, F J Sánchez; Frenich, A Garrido
2004-10-01
A method has been developed for the simultaneous determination of paraquat (PQ), deiquat (DQ), chlormequat (CQ) and mepiquat (MQ) in water samples by liquid chromatography (LC) coupled with electrospray ionization mass spectrometry (MS). The LC separations of the target compounds, as well as their MS parameters, were optimized in order to improve selectivity and sensitivity. Separation was carried out in a Xterra C8 column, using as mobile phase methanol-heptafluorobutyric acid (HFBA) in isocratic mode. The molecular ion was selected for the quantitation in selected ion monitoring (SIM) mode. Off-line solid-phase extraction (SPE) was applied with silica cartridges in order to preconcentrate the compounds from waters. Detection limits were in the range 0.02-0.40 microg l(-1). Recovery range varied between 89 and 99.5% with precision values lower than 6%. The method has been applied successfully to the analysis of both surface and groundwater samples from agricultural areas of Andalusia (Spain), using well defined internal quality control (IQC) criteria. The results revealed the presence of deiquat and paraquat in some samples.
Vaurio, Linnea; Riley, Edward P.; Mattson, Sarah N.
2012-01-01
An objective in current research on children with fetal alcohol spectrum disorders (FASD) is to determine neurobehavioral profiles to identify affected individuals. Deficits observed when children with FASD are compared to typically developing controls may be confounded by lower IQ scores in the subjects with FASD. To determine if prenatal alcohol exposure is associated with neurobehavioral deficits after controlling for IQ differences, multivariate analyses were conducted to compare alcohol-exposed (ALC) subjects to a comparison group closely matched on IQ (IQC). The initial analysis included a broad neuropsychological battery with measures of language, executive function, visual–motor integration, motor ability, and academic achievement. Additional, in depth comparisons focused on visual sustained attention, verbal learning and memory and parent/guardian-reported behavior problems. Group differences (ALC < IQC) were found on verbal learning and parent-rated behavior problems. Group differences were marginally significant (measures within the broad neuropsychological comparison) or not significant (visual attention, retention of verbal material) on the remaining comparisons. Therefore, some deficits (e.g., verbal learning and behavior problems) in children with heavy prenatal alcohol exposure cannot be explained by the lower FSIQ observed in the population. These areas of relative weakness could be useful in distinguishing children with FASD from other children with lowered IQ. PMID:21349236
Image quality classification for DR screening using deep learning.
FengLi Yu; Jing Sun; Annan Li; Jun Cheng; Cheng Wan; Jiang Liu
2017-07-01
The quality of input images significantly affects the outcome of automated diabetic retinopathy (DR) screening systems. Unlike the previous methods that only consider simple low-level features such as hand-crafted geometric and structural features, in this paper we propose a novel method for retinal image quality classification (IQC) that performs computational algorithms imitating the working of the human visual system. The proposed algorithm combines unsupervised features from saliency map and supervised features coming from convolutional neural networks (CNN), which are fed to an SVM to automatically detect high quality vs poor quality retinal fundus images. We demonstrate the superior performance of our proposed algorithm on a large retinal fundus image dataset and the method could achieve higher accuracy than other methods. Although retinal images are used in this study, the methodology is applicable to the image quality assessment and enhancement of other types of medical images.
Mekonen, Ayehu; Ayele, Yeshi; Berhan, Yifru; Woldeyohannes, Desalegn; Erku, Woldaregay; Sisay, Solomon
2018-01-01
Quality of tuberculosis (TB) microscopy diagnosis is not a guarantee despite implementation of External Quality Assurance (EQA) service in all laboratories of health facilities. Hence, we aimed at evaluating the technical quality and the findings of sputum smear microscopy for acid fast bacilli (AFB) at health centers in Hararge Zone, Oromia Region, Ethiopia. A cross-sectional study was carried out between July 8, 2014 and July 7, 2015.A pre-tested structured questionnaire was used to collect data. Lot Quality Assurance Sampling (LQAS) method was put into practice for collecting all necessary sample slides. Data were analyzed by using SPSS (Statistical Package for Social Sciences) version 20 software. P-value < 0.05 was considered as statistically significant. Of the total55 health center laboratories which had been assessed during the study period, 20 (36.4%) had major technical errors; 13 (23.6%) had 15 false negative results and 17 (30.9%) had 22 false positive results. Moreover, poor specimen quality, smear size, smear thickness, staining and evenness were indicated in 40 (72.7%), 39 (70.9%), 37 (67.3%), 27(49.1%) and 37 (67.3%) of the collected samples, respectively. False negative AFB findings were significantly associated with lack of Internal Quality Control (IQC) measures (AOR (Adjusted Odds Ratio): 2.90 (95% CI (Confidence Interval): 1.25,6.75) and poor staining procedures (AOR: 2.16(95% CI: 1.01, 5.11). The qualities of AFB smear microscopy reading and smearing were low in most of the laboratories of the health centers. Therefore, it is essential to strength EQA program through building the capacity of laboratory professionals.
Farrance, Ian; Frenkel, Robert
2014-01-01
The Guide to the Expression of Uncertainty in Measurement (usually referred to as the GUM) provides the basic framework for evaluating uncertainty in measurement. The GUM however does not always provide clearly identifiable procedures suitable for medical laboratory applications, particularly when internal quality control (IQC) is used to derive most of the uncertainty estimates. The GUM modelling approach requires advanced mathematical skills for many of its procedures, but Monte Carlo simulation (MCS) can be used as an alternative for many medical laboratory applications. In particular, calculations for determining how uncertainties in the input quantities to a functional relationship propagate through to the output can be accomplished using a readily available spreadsheet such as Microsoft Excel. The MCS procedure uses algorithmically generated pseudo-random numbers which are then forced to follow a prescribed probability distribution. When IQC data provide the uncertainty estimates the normal (Gaussian) distribution is generally considered appropriate, but MCS is by no means restricted to this particular case. With input variations simulated by random numbers, the functional relationship then provides the corresponding variations in the output in a manner which also provides its probability distribution. The MCS procedure thus provides output uncertainty estimates without the need for the differential equations associated with GUM modelling. The aim of this article is to demonstrate the ease with which Microsoft Excel (or a similar spreadsheet) can be used to provide an uncertainty estimate for measurands derived through a functional relationship. In addition, we also consider the relatively common situation where an empirically derived formula includes one or more ‘constants’, each of which has an empirically derived numerical value. Such empirically derived ‘constants’ must also have associated uncertainties which propagate through the functional relationship and contribute to the combined standard uncertainty of the measurand. PMID:24659835
Farrance, Ian; Frenkel, Robert
2014-02-01
The Guide to the Expression of Uncertainty in Measurement (usually referred to as the GUM) provides the basic framework for evaluating uncertainty in measurement. The GUM however does not always provide clearly identifiable procedures suitable for medical laboratory applications, particularly when internal quality control (IQC) is used to derive most of the uncertainty estimates. The GUM modelling approach requires advanced mathematical skills for many of its procedures, but Monte Carlo simulation (MCS) can be used as an alternative for many medical laboratory applications. In particular, calculations for determining how uncertainties in the input quantities to a functional relationship propagate through to the output can be accomplished using a readily available spreadsheet such as Microsoft Excel. The MCS procedure uses algorithmically generated pseudo-random numbers which are then forced to follow a prescribed probability distribution. When IQC data provide the uncertainty estimates the normal (Gaussian) distribution is generally considered appropriate, but MCS is by no means restricted to this particular case. With input variations simulated by random numbers, the functional relationship then provides the corresponding variations in the output in a manner which also provides its probability distribution. The MCS procedure thus provides output uncertainty estimates without the need for the differential equations associated with GUM modelling. The aim of this article is to demonstrate the ease with which Microsoft Excel (or a similar spreadsheet) can be used to provide an uncertainty estimate for measurands derived through a functional relationship. In addition, we also consider the relatively common situation where an empirically derived formula includes one or more 'constants', each of which has an empirically derived numerical value. Such empirically derived 'constants' must also have associated uncertainties which propagate through the functional relationship and contribute to the combined standard uncertainty of the measurand.
Ustundag-Budak, Yasemin; Huysal, Kagan
2017-02-01
Electrolytes have a narrow range of biological variation and small changes are clinically significant. It is important to select the best method for clinical decision making and patient monitoring in the emergency room. The sigma metrics model provides an objective method to evaluate the performance of a method. To calculate sigma metrics for electrolytes measured with one arterial blood gas analyser including two auto-analysers that use different technologies. To identify the best approach for electrolyte monitoring in an emergency setting and the context of routine emergency room workflow. The Coefficient of Variation (CV) was determined from Internal Quality Control (IQC). Data was measured from July 2015 to January 2016 for all three analysers. The records of KBUD external quality data (Association of Clinical Biochemists, Istanbul, Turkey) for both Mindray BS-2000M analyser (Mindray, Shenzhen, China) and Architect C16000 (Abbott Diagnostics, Abbott Park, IL) and MLE clinical laboratory evaluation program (Washington, DC, USA) for Radiometer ABL 700 (Radiometer Trading, Copenhagen, Denmark) during the study period were used to determine the bias. The calculated average sigma values for sodium (-1.1), potassium (3.3), and chloride (0.06) were with the Radiometer ABL700. All calculated sigma values were better than the auto-analysers. The sigma values obtained from all analysers suggest that running more controls and increasing the calibration frequency for electrolytes is necessary for quality assurance.
Barnett, David; Whitby, Liam; Wong, John; Louzao, Raul; Reilly, John T; Denny, Thomas N
2012-03-01
The aim of clinical laboratories is to produce accurate and reproducible results to enable effective and reliable clinical practice and patient management. The standard approach is to use both internal quality control (IQC) and external quality assessment (EQA). IQC serves, in many instances, as a "go, no go" tool to provide real time assurance that instruments and reagent or test systems are performing within defined specifications. EQA however, takes a snapshot at a specific point in time of the full testing process, results are compared to other laboratories performing similar testing but inevitably has some built in delay from sample issue to performance data review. In addition, if IQC or EQA identify areas of concern it can be difficult to determine the exact nature of the problem. In an attempt to address this problem, we have developed an instant QA panel that we have termed VERIQAS™, specifically for CD4(+) T lymphocyte counting, and have undertaken a "proof of principle" pilot study to examine how the use of VERIQAS™ could result in improvement of laboratory performance. In addition, we have examined how this approach could be used as a training and education tool (in a domestic/international setting) and potentially be of value in instrument validation/switch studies (a switch study being defined as a laboratory changing from one method/instrument to a new method/instrument with the VERIQAS™ panel being used as an adjunct to their standard switch study protocol). The basic panel consists of 20 stabilized samples, with predefined CD4(+) T lymphocyte counts, that span low clinically relevant to normal counts, including some blinded replicates (singlet up to quadruplicate combinations). The CD4(+) T lymphocyte target values for each specimen is defined as the trimmed mean ± 2 trimmed standard deviations, where the trimmed values are derived from the CD4(+) T lymphocyte counts reported by the participating centers (~780 laboratories) that receive each UK NEQAS for Leucocyte Immunophenotyping send out. Results for the VERIQAS™ panel were returned online, via a specially designed website, and the participant was provided with an immediate assessment (pass or fail). To date, the panel has been preliminary trialed by eight laboratories to (i) assess pre-EQA qualification (two laboratories); (ii) address performance issues (two laboratories); or (iii) validate new instruments or techniques (four laboratories). Interestingly, even in this pilot study, the panel has been instrumental in identifying specific technical problems in laboratories with EQA performance issues as well as confirming that implementation of new techniques or instruments have been successful. We report here a new and novel "proof of principle" pilot study to quality assessment, that we have termed VERIQAS™, designed to provide instant feedback on performance. Participating laboratories receive 20 "blinded" samples that are in singlet up to quadruplicate combinations. Once a centre reports its results via a website, immediate feedback is provided to both the participant and the EQA organizers, enabling, if required, the initiation of targeted remedial action. We have also shown that this approach has the potential to be used as a tool for prequalification, troubleshooting, training and instrument verification. Pilot phase field trials with VERIQAS™ have shown that the panel can highlight laboratory performance problems, such as suboptimal instrument set up, pipetting and gating strategies, in a rapid and efficient manner. VERIQAS™ will now be introduced, where appropriate, as a second phase study within UK NEQAS for Leucocyte Immunophenotyping to assist those laboratories that have performance issues and also made available to laboratories for training and education of staff and instrument validation studies. Copyright © 2011 International Clinical Cytometry Society.
Weak crystallization theory of metallic alloys
Martin, Ivar; Gopalakrishnan, Sarang; Demler, Eugene A.
2016-06-20
Crystallization is one of the most familiar, but hardest to analyze, phase transitions. The principal reason is that crystallization typically occurs via a strongly first-order phase transition, and thus rigorous treatment would require comparing energies of an infinite number of possible crystalline states with the energy of liquid. A great simplification occurs when crystallization transition happens to be weakly first order. In this case, weak crystallization theory, based on unbiased Ginzburg-Landau expansion, can be applied. Even beyond its strict range of validity, it has been a useful qualitative tool for understanding crystallization. In its standard form, however, weak crystallization theorymore » cannot explain the existence of a majority of observed crystalline and quasicrystalline states. Here we extend the weak crystallization theory to the case of metallic alloys. In this paper, we identify a singular effect of itinerant electrons on the form of weak crystallization free energy. It is geometric in nature, generating strong dependence of free energy on the angles between ordering wave vectors of ionic density. That leads to stabilization of fcc, rhombohedral, and icosahedral quasicrystalline (iQC) phases, which are absent in the generic theory with only local interactions. Finally, as an application, we find the condition for stability of iQC that is consistent with the Hume-Rothery rules known empirically for the majority of stable iQC; namely, the length of the primary Bragg-peak wave vector is approximately equal to the diameter of the Fermi sphere.« less
Glencross, Deborah K; Janossy, George; Coetzee, Lindi M; Lawrie, Denise; Aggett, Hazel M; Scott, Lesley E; Sanne, Ian; McIntyre, James A; Stevens, Wendy
2008-01-01
In order to expand the treatment of human immunodeficiency virus-1 (HIV) infected patients in Africa, millions will require cost-effective CD4 counts. Supporting laboratories therefore, need to move away from crisis management and haphazard practices to organized pathology services. The authors reviewed the performance of the simplified single platform (SP) PanLeucogated (PLG) CD4 methodology, introduced into 52 laboratories across the South African National Health Laboratory Service (SA-NHLS), with a proactive approach to training, internal quality control (IQC), and external quality assessment (EQA). Two-color flow cytometry for SP PLG (CD4/CD45) was combined with the sample-by-sample bead-count-rate (BCR) IQC for bead pipetting. PLG + BCR was validated versus conventional predicate SP and dual-platform (DP) 4-color flow cytometric methods used in the first world-on 1181 samples from 250 HIV+ patients followed longitudinally on anti-retroviral therapy (ART). EQA (accuracy) was performed through the United Kingdom National External Quality Assessment Scheme (UK-NEQAS). Further EQA was performed across the 52 SA-NHLS SP-PLG laboratories participating on the CD4 African Regional External Quality Assessment Scheme (AFREQAS), to assess both accuracy and/precision between NHLS PLG laboratories. There was virtually no bias noted between SP PLG and SP predicate methods. On DP, bias and variability increased but the errors introduced were minor without affecting CD4-related clinical decisions. The simpler 2-color PLG was less expensive with additional advantages: CD4+ T-cells were discriminated from monocytes without a need for CD3-staining, and the training was faster and easier for the trainees and trainers alike. The accuracy of SP-PLG was satisfactory: all PLG results submitted to the UK NEQAS were within +/-1 Trimmed Standard Deviation (SD) of the UK NEQAS CD4 Pool Trimmed Mean. Further, on the CD4 AFREQAS, the SA-NHLS laboratories using SP-PLG + BCR showed better precision (mean %CV = 7.2%) than the CD4 methods employed in other laboratories in Africa (mean %CV = 10.7%) or on other continents (mean %CV = 12.9%). PLG + BCR accommodated high workloads, exceeding 3,000 tests/laboratory/month, with capacity for further growth around 10% per month across the SA-NHLS. The superior performance of PLG + BCR over other methods has been demonstrated. In resource-conscious countries, where large-scale ART is being introduced, flow-cytometry using PLG + BCR can make a significant impact-due to simpler operation, easier training, stricter quality assurance, and better cost-efficiency. These cost-effective flow methods can legitimately replace the more cumbersome predicate technology of the first world for ART monitoring whilst accommodating an ever-expanding national ART program and consequent extremely high workloads reached country-wide. Copyright 2008 Clinical Cytometry Society.
Bukve, Tone; Røraas, Thomas; Riksheim, Berit Oddny; Christensen, Nina Gade; Sandberg, Sverre
2015-01-01
The Norwegian Quality Improvement of Primary Care Laboratories (Noklus) offers external quality assurance (EQA) schemes (EQASs) for urine albumin (UA) annually. This study analyzed the EQA results to determine how the analytical quality of UA analysis in general practice (GP) offices developed between 1998 (n=473) and 2012 (n=1160). Two EQA urine samples were distributed yearly to the participants by mail. The participants measured the UA of each sample and returned the results together with information about their instrument, the profession and number of employees at the office, frequency of internal quality control (IQC), and number of analyses per month. In the feedback report, they received an assessment of their analytical performance. The number of years that the GP office had participated in Noklus was inversely related to the percentage of "poor" results for quantitative but not semiquantitative instruments. The analytical quality improved for participants using quantitative instruments who received an initial assessment of "poor" and who subsequently changed their instrument. Participants using reagents that had expired or were within 3 months of the expiration date performed worse than those using reagents that were expiring in more than 3 months. Continuous participation in the Noklus program improved the performance of quantitative UA analyses at GP offices. This is probably in part attributable to the complete Noklus quality system, whereby in addition to participating in EQAS, participants are visited by laboratory consultants who examine their procedures and provide practical advice and education regarding the use of different instruments.
NASA Astrophysics Data System (ADS)
Naglič, Iztok; Samardžija, Zoran; Delijić, Kemal; Kobe, Spomenka; Leskovar, Blaž; Markoli, Boštjan
2018-05-01
An Al-Mn alloy with additions of copper, magnesium, and silicon was prepared and cast into a copper mold. It contains in situ-formed icosahedral quasicrystals (iQCs), as confirmed by electron backscatter diffraction. The aim of this work is to present the mechanical and corrosion properties of this alloy and compare its properties with some conventional commercial materials. The compressive strength and compressive yield strength were 751 MPa and 377 MPa, while the compressive fracture strain was 19%. It was observed that intensive shearing caused the final fracture of the specimens and the fractured iQC dendrites still showed cohesion with the α-Al matrix. The polarization resistance and corrosion rate of the artificially aged alloy were 7.30 kΩ and 1.2 μm/year. The evaluated properties are comparable to conventional, discontinuously reinforced aluminum metal-matrix composites and structural wrought aluminum alloys.
Product development studies of amino acid conjugate of Aceclofenac.
Singh, Ajay Pal; Ramadan, Wafa Mossa; Dahiya, Rajiv; Sarpal, A S; Pathak, Kamla
2009-04-01
The prodrugs designed by classical approach increase lipophilicity of the drug, which decreases the water solubility thus decreasing the concentration gradient, which controls drug absorption. To overcome the limitations of traditional prodrug approach, water soluble prodrugs can be designed by adding selected amino acid to the drug moiety that are the substrates for the enzyme located at the intestinal brush border thus overcoming pharmaceutical problem without compromising bioavailability. ACaa (Amino acid conjugate of Aceclofenac) was synthesized by conjugation with l-phenylalanine by conventional coupling method using N, N-dicyclohexylcarbodiimide and ACaa was characterized by melting point, TLC, photomicrograph, UV, FT-IR, FT-NMR, MS-FAB, XRD and DSC. As a part of product development study ACaa was subjected to studies like In-vivo in albino rats and in-vitro like ACaa reversion to AC (Aceclofenac) in aqueous buffers of pH 1.21, 2.38. 3.10, 6.22 and 7.41, at a constant concentration (0.05M), ionic strength (micro = 0.5) and at a temperature of 37 degrees C +/- 0.5 degrees C, ACaa showed negligible reversion (2.15 %) up to 24 hrs study at acidic pH thus suggesting stability in acidic environment of stomach, the rate of reversion increased as pH of medium increased. pH- partition profile, pH- solubility profile and micromeritic studies were also carried out in comparison to pure drug. The solubility and lipophilicity of ACaa exhibited higher values at all pH range when compared to AC. The micromeritic properties also evaluated in terms of particle shape and size, IQCS and kurtosis. Resulting IQCS value approached zero thus suggesting reducing in the degree of skewness.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pham, Joyce; Meng, Fanqiang; Lynn, Matthew J.
The irreversible transformation from an icosahedral quasicrystal (i-QC) CaAu 4.39Al 1.61 to its cubic 2/1 crystalline approximant (CA) Ca 13Au 56.31(3)Al 21.69 (CaAu 4.33(1)Al1.67, Pamore » $$\\bar{3}$$ (No. 205); Pearson symbol: cP728; a = 23.8934(4)), starting at ~570 °C and complete by ~650 °C, is discovered from in situ, high-energy, variable-temperature powder X-ray diffraction (PXRD), thereby providing direct experimental evidence for the relationship between QCs and their associated CAs. The new cubic phase crystallizes in a Tsai-type approximant structure under the broader classification of polar intermetallic compounds, in which atoms of different electronegativities, viz., electronegative Au + Al vs electropositive Ca, are arranged in concentric shells. From a structural chemical perspective, the outermost shell of this cubic approximant may be described as interpenetrating and edge-sharing icosahedra, a perspective that is obtained by splitting the traditional structural description of this shell as a 92-atom rhombic triacontahedron into an 80-vertex cage of primarily Au [Au 59.86(2)Al 17.14⟂ 3.00] and an icosahedral shell of only Al [Al 10.5⟂ 1.5]. Following the proposal that the cubic 2/1 CA approximates the structure of the i-QC and on the basis of the observed transformation, an atomic site analysis of the 2/1 CA, which shows a preference to maximize the number of heteroatomic Au–Al nearest neighbor contacts over homoatomic Al–Al contacts, implies a similar outcome for the i-QC structure. Analysis of the most intense reflections in the diffraction pattern of the cubic 2/1 CA that changed during the phase transformation shows correlations with icosahedral symmetry, and the stability of this cubic phase is assessed using valence electron counts. Finally, according to electronic structure calculations, a cubic 1/1 CA, “Ca 24Au 88Al 64” (CaAu 3.67Al 2.67) is proposed.« less
Pham, Joyce; Meng, Fanqiang; Lynn, Matthew J.; ...
2017-12-29
The irreversible transformation from an icosahedral quasicrystal (i-QC) CaAu 4.39Al 1.61 to its cubic 2/1 crystalline approximant (CA) Ca 13Au 56.31(3)Al 21.69 (CaAu 4.33(1)Al1.67, Pamore » $$\\bar{3}$$ (No. 205); Pearson symbol: cP728; a = 23.8934(4)), starting at ~570 °C and complete by ~650 °C, is discovered from in situ, high-energy, variable-temperature powder X-ray diffraction (PXRD), thereby providing direct experimental evidence for the relationship between QCs and their associated CAs. The new cubic phase crystallizes in a Tsai-type approximant structure under the broader classification of polar intermetallic compounds, in which atoms of different electronegativities, viz., electronegative Au + Al vs electropositive Ca, are arranged in concentric shells. From a structural chemical perspective, the outermost shell of this cubic approximant may be described as interpenetrating and edge-sharing icosahedra, a perspective that is obtained by splitting the traditional structural description of this shell as a 92-atom rhombic triacontahedron into an 80-vertex cage of primarily Au [Au 59.86(2)Al 17.14⟂ 3.00] and an icosahedral shell of only Al [Al 10.5⟂ 1.5]. Following the proposal that the cubic 2/1 CA approximates the structure of the i-QC and on the basis of the observed transformation, an atomic site analysis of the 2/1 CA, which shows a preference to maximize the number of heteroatomic Au–Al nearest neighbor contacts over homoatomic Al–Al contacts, implies a similar outcome for the i-QC structure. Analysis of the most intense reflections in the diffraction pattern of the cubic 2/1 CA that changed during the phase transformation shows correlations with icosahedral symmetry, and the stability of this cubic phase is assessed using valence electron counts. Finally, according to electronic structure calculations, a cubic 1/1 CA, “Ca 24Au 88Al 64” (CaAu 3.67Al 2.67) is proposed.« less
The External Quality Assessment Scheme (EQAS): Experiences of a medium sized accredited laboratory.
Bhat, Vivek; Chavan, Preeti; Naresh, Chital; Poladia, Pratik
2015-06-15
We put forth our experiences of EQAS, analyzed the result discrepancies, reviewed the corrective actions and also put forth strategies for risk identification and prevention of potential errors in a medical laboratory. For hematology, EQAS samples - blood, peripheral and reticulocyte smears - were received quarterly every year. All the blood samples were processed on HMX hematology analyzer by Beckman-Coulter. For clinical chemistry, lyophilized samples were received and were processed on Siemens Dimension Xpand and RXL analyzers. For microbiology, EQAS samples were received quarterly every year as lyophilized strains along with smears and serological samples. In hematology no outliers were noted for reticulocyte and peripheral smear examination. Only one outlier was noted for CBC. In clinical chemistry outliers (SDI ≥ 2) were noted in 7 samples (23 parameters) out of total 36 samples (756 parameters) processed. Thirteen of these parameters were analyzed as random errors, 3 as transcriptional errors and seven instances of systemic error were noted. In microbiology, one discrepancy was noted in isolate identification and in the grading of smears for AFB by Ziehl Neelsen stain. EQAS along with IQC is a very important tool for maintaining optimal quality of services. Copyright © 2015 Elsevier B.V. All rights reserved.
Quasicrystal structure and growth models: discussion of the status quo and the still open questions
NASA Astrophysics Data System (ADS)
Steurer, Walter
2017-02-01
Where are we now in quasicrystal (QC) research more than three decades after Dan Shechtman’s discovery? Do we fully understand the origin of quasiperiodicity, the formation, growth, thermodynamic stability, structure and properties of quasicrystals? First, I will shortly present the status quo, then I will address the still open questions, and identify potential focus areas for future research. Because of the limited space, I will focus on decagonal quasicrystals (DQCs); the status quo for research on icosahedral quasicrystals (IQCs) is comparable.
Comparison between bottom-up and top-down approaches in the estimation of measurement uncertainty.
Lee, Jun Hyung; Choi, Jee-Hye; Youn, Jae Saeng; Cha, Young Joo; Song, Woonheung; Park, Ae Ja
2015-06-01
Measurement uncertainty is a metrological concept to quantify the variability of measurement results. There are two approaches to estimate measurement uncertainty. In this study, we sought to provide practical and detailed examples of the two approaches and compare the bottom-up and top-down approaches to estimating measurement uncertainty. We estimated measurement uncertainty of the concentration of glucose according to CLSI EP29-A guideline. Two different approaches were used. First, we performed a bottom-up approach. We identified the sources of uncertainty and made an uncertainty budget and assessed the measurement functions. We determined the uncertainties of each element and combined them. Second, we performed a top-down approach using internal quality control (IQC) data for 6 months. Then, we estimated and corrected systematic bias using certified reference material of glucose (NIST SRM 965b). The expanded uncertainties at the low glucose concentration (5.57 mmol/L) by the bottom-up approach and top-down approaches were ±0.18 mmol/L and ±0.17 mmol/L, respectively (all k=2). Those at the high glucose concentration (12.77 mmol/L) by the bottom-up and top-down approaches were ±0.34 mmol/L and ±0.36 mmol/L, respectively (all k=2). We presented practical and detailed examples for estimating measurement uncertainty by the two approaches. The uncertainties by the bottom-up approach were quite similar to those by the top-down approach. Thus, we demonstrated that the two approaches were approximately equivalent and interchangeable and concluded that clinical laboratories could determine measurement uncertainty by the simpler top-down approach.
An outline of a risk assessment-based system of meat safety assurance and its future prospects.
Berends, B R; van Knapen, F
1999-10-01
Discussed are the outlines of a risk assessment-based system of meat safety assurance to replace the current meat inspection. An example of a system that uses the Hazard Analysis of Critical Control Points (HACCP)-principles in the entire production chain from stable to table is also given. Continuous evaluation of risks is the main driving force of the new system. Only then the system has the means to remain flexible and provide for the data necessary to convince trade partners that the products they buy are safe. A monitoring system that keeps track of the important health hazards in the entire chain from stable to table is therefore necessary. This includes monitoring of cases of disease in the human population caused by the hazardous agents of concern. Coordination of the monitoring and control and processing of the information is done by an independent body. Furthermore, the system demands a production from stable to table that is based on the ideas of Integrated Quality Control (IQC), HACCP, and certification of production processes and quality control procedures. Clear legislation provides for criteria about acceptable or unacceptable health risks for the consumer and determines at what moments which risks should be controlled by the producers. Simultaneously, the legislation has to be flexible enough to be able to adapt quickly to any changes in risks, or in the way risks should be controlled. In the new system current meat inspection can easily be carried out by employees of the slaughter houses and is no longer a direct responsibility of the authorities. The authorities only demand certain safety levels and verify whether producers stick to these. Producers remain fully responsible for the safety and quality of their products, and fully liable in case of any damage to the consumers' health. However, it is to be expected that some EU Member-States miss the organizational and agricultural basis for a successful application of the new system. Consequences are that two parallel flows of meat and meat products may come to existence. One flow will exist of meat produced according to the new, and with respect to safety assurance, superior system. The other flow will consist of meat produced and inspected in the traditional way. However, this meat will contain all the flaws that required a revision of the system in the first place. This, and the fact that EU policy ordains that part-taking in an alternative meat inspection system should be voluntary, may very well result in a very slow start-up of the new system. One of the easiest solutions, however, would be to implement a decontamination step in the slaughtering process, provided that this is accompanied by strict codes of hygienic practices and good manufacturing practices. Not only would this lead to safer meat, but also result in the two separate flows of meat becoming one flow again as well as an easier to organize livestock production according to HACCP-principles.
Martin, Richard M.; Patel, Rita; Oken, Emily; Thompson, Jennifer; Zinovik, Alexander; Kramer, Michael S.; Vilchuck, Konstantin; Bogdanovich, Natalia; Sergeichick, Natalia; Foo, Ying; Gusina, Nina
2013-01-01
Background Adiponectin is an adipocyte-derived hormone that acts as a marker of insulin sensitivity. Bloodspot sampling by fingerstick onto filter paper may increase the feasibility of large-scale studies of the determinants of insulin sensitivity. We first describe the validation of an enzyme-linked immunoassay (ELISA) for quantifying adiponectin from dried blood spots and then demonstrate its application in a large trial (PROBIT). Methods We quantified adiponectin from 3-mm diameter discs (≈3 µL of blood) punched from dried blood spots obtained from: i) whole blood standards (validation); and ii) PROBIT trial samples (application) in which paediatricians collected blood spots from 13,879 children aged 11.5 years from 31 sites across Belarus. We examined the distribution of bloodspot adiponectin by demographic and anthropometric factors, fasting insulin and glucose. Results In the validation study, mean intra-assay coefficients of variation (n = 162) were 15%, 13% and 10% for ‘low’ (6.78 µg/ml), ‘medium’ (18.18 µg/ml) and 'high’ (33.13 µg/ml) internal quality control (IQC) samples, respectively; the respective inter-assay values (n = 40) were 23%, 21% and 14%. The correlation coefficient between 50 paired whole bloodspot versus plasma samples, collected simultaneously, was 0.87 (95% CI: 0.78 to 0.93). Recovery of known quantities of adiponectin (between 4.5 to 36 µg/ml) was 100.3–133%. Bloodspot adiponectin was stable for at least 30 months at −80°C. In PROBIT, we successfully quantified fasting adiponectin from dried blood spots in 13,329 of 13,879 (96%) children. Mean adiponectin (standard deviation) concentrations were 17.34 µg/ml (7.54) in boys and 18.41 µg/ml (7.92) in girls and were inversely associated with body mass index, fat mass, triceps and subscapular skin-fold thickness, waist circumference, height and fasting glucose. Conclusions Bloodspot ELISA is suitable for measuring adiponectin in very small volumes of blood collected on filter paper and can be applied to large-scale studies. PMID:23936498
The Application of Six Sigma Techniques in the Evaluation of Enzyme Measurement Procedures in China.
Zhang, Chuanbao; Zhao, Haijian; Wang, Jing; Zeng, Jie; Wang, Zhiguo
2015-01-01
Recently, Six Sigma techniques have been adopted by clinical laboratories to evaluate laboratory performance. Measurement procedures in laboratories can be categorized as "excellent", "good", and "improvement needed" based on sigma (σ) metrics of σ ≥ 6, 3 ≤ σ < 6, and σ < 3, respectively. The quality goal index (QGI) was further investigated for measurement procedures with σ ≤ 3. Improvements of the procedures were recommended based on QGI: QGI < 0.8 indicates that the precision of the procedure needs to be improved; QGI > 1.2 indicates that the trueness of the procedure needs to be improved; 0.8 ≤ QGI ≤ 1.2 indicates that both the precision and trueness of the procedure need to be improved. Fresh frozen sera containing seven enzymes (ALT, ALP, AMY, AST, CK, GGT, and LDH) were sent to 78 clinical laboratories in China. The biases for measurement procedures in each laboratory (Bias) were calculated based on the target values assigned by 18 laboratories performing IFCC (International Federation of Clinical Chemistry and Laboratory medicine) recommended reference methods. The imprecision of each measurement procedure was represented by coefficient variations (CV) calculated based on internal quality control (IQC) data. The σ and QGI values were calculated as follows: σ = (TEa-Bias)/CV; QGI = Bias/(1.5 x CV). TEa is allowable total error for each enzyme derived from biological variation. Our study indicated that 7.9% (6/76, ALP) to 31.0% (18/58, AMY) of the participating laboratories were scored as "excellent" (σ ≥ 6), 21.1% (16/76, ALP) to 41.3% (31/75, CK) of the laboratories were scored as "good" (3 ≤ σ < 6), and 31.0% (18/58, AMY) to 71.1% (54/76, ALP) of the laboratories need to improve their enzyme measurement procedures (σ < 3). For those with σ < 3, QGIs were further calculated. Based on QGI values, 8.6% (5/58, AMY) to 35.9% (28/78, LDH) of the laboratories (QGI < 0.8) need to improve the precision of the procedures, 8.0% (6/75, CK) to 52.6% (40/76, ALP) of the laboratories (QGI ≤ 1.2) need to improve the trueness of the procedures; and 2.7% (2/75, AST) to 16.3% (8/49, GGT) of the laboratories (0.8 ≤ QGI ≤ 1.2) need to improve both the precision and trueness of the procedures. Even though rapid progress has been made to standardize serum enzyme measurements in China in recent years, our study using Six Sigma techniques still suggested that approximately 31.1% to 71.0% of the laboratories need to improve their enzyme measurement procedures, either in terms of precision, trueness, or both.
1984-01-01
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NASA Astrophysics Data System (ADS)
Hu, S. X.; Michel, D. T.; Edgell, D. H.; Froula, D. H.; Follett, R. K.; Goncharov, V. N.; Myatt, J. F.; Skupsky, S.; Yaakobi, B.
2013-03-01
Direct-drive-ignition designs with plastic CH ablators create plasmas of long density scale lengths (Ln ≥ 500 μm) at the quarter-critical density (Nqc) region of the driving laser. The two-plasmon-decay (TPD) instability can exceed its threshold in such long-scale-length plasmas (LSPs). To investigate the scaling of TPD-induced hot electrons to laser intensity and plasma conditions, a series of planar experiments have been conducted at the Omega Laser Facility with 2-ns square pulses at the maximum laser energies available on OMEGA and OMEGA EP. Radiation-hydrodynamic simulations have been performed for these LSP experiments using the two-dimensional hydrocode draco. The simulated hydrodynamic evolution of such long-scale-length plasmas has been validated with the time-resolved full-aperture backscattering and Thomson-scattering measurements. draco simulations for CH ablator indicate that (1) ignition-relevant long-scale-length plasmas of Ln approaching ˜400 μm have been created; (2) the density scale length at Nqc scales as Ln(μm)≃(RDPP×I1/4/2); and (3) the electron temperature Te at Nqc scales as Te(keV)≃0.95×√I , with the incident intensity (I) measured in 1014 W/cm2 for plasmas created on both OMEGA and OMEGA EP configurations with different-sized (RDPP) distributed phase plates. These intensity scalings are in good agreement with the self-similar model predictions. The measured conversion fraction of laser energy into hot electrons fhot is found to have a similar behavior for both configurations: a rapid growth [fhot≃fc×(Gc/4)6 for Gc < 4] followed by a saturation of the form, fhot≃fc×(Gc/4)1.2 for Gc ≥ 4, with the common wave gain is defined as Gc=3 × 10-2×IqcLnλ0/Te, where the laser intensity contributing to common-wave gain Iqc, Ln, Te at Nqc, and the laser wavelength λ0 are, respectively, measured in [1014 W/cm2], [μm], [keV], and [μm]. The saturation level fc is observed to be fc ≃ 10-2 at around Gc ≃ 4. The hot-electron temperature scales roughly linear with Gc. Furthermore, to mitigate TPD instability in long-scale-length plasmas, different ablator materials such as saran and aluminum have been investigated on OMEGA EP. Hot-electron generation has been reduced by a factor of 3-10 for saran and aluminum plasmas, compared to the CH case at the same incident laser intensity. draco simulations suggest that saran might be a better ablator for direct-drive-ignition designs as it balances TPD mitigation with an acceptable hydro-efficiency.
Liu, Xin; Hong, Xiumei; Tsai, Hui-Ju; Mestan, Karen K.; Shi, Min; Kefi, Amira; Hao, Ke; Chen, Qi; Wang, Guoying; Caruso, Deanna; Geng, Hua; Gao, Yufeng; He, Jianlin; Kumar, Rajesh; Wang, Hongjian; Yu, Yunxian; Bartell, Tami; Tan, Xiao-Di; Schleimer, Robert P.; Weeks, Daniel E.; Pongracic, Jacqueline A.; Wang, Xiaobin
2018-01-01
Abstract Previous genetic studies of food allergy (FA) have mainly focused on inherited genotypic effects. The role of parental genotypic effects remains largely unexplored. Leveraging existing genome-wide association study (GWAS) data generated from the Chicago Food Allergy Study, we examined maternal genotypic and parent-of-origin (PO) effects using multinomial likelihood ratio tests in 588 complete and incomplete Caucasian FA trios. We identified 1 single nucleotide polymorphism with significant (P < 5×10−8) maternal effect on any FA (rs4235235), which is located in a noncoding RNA (LOC101927947) with unknown function. We also identified 3 suggestive (P < 5×10−7) loci with maternal genetic effects: 1 for any FA (rs976078, in a gene desert region on 13q31.1) and 2 for egg allergy (rs1343795 and rs4572450, in the ZNF652 gene, where genetic variants have been associated with atopic dermatitis). Three suggestive loci with PO effect were observed: 1 for peanut allergy (rs4896888 in the ADGB gene) and 2 for any FA in boys only (rs1036504 and rs2917750 in the IQCE gene). Findings from this family-based GWAS of FA provided some preliminary evidence on maternal genotypic or PO effects on FA. Additional family-based studies are needed to confirm our findings and gain new insight into maternal and paternal genetic contribution to FA. PMID:29489655
DOE Office of Scientific and Technical Information (OSTI.GOV)
Karaköse, Ercan, E-mail: ekarakose@karatekin.edu.t
2016-11-15
The present work examines the effect of Mg contents and cooling rate on the morphology and mechanical properties of Al{sub 20}Cu{sub 12}Fe quasicrystalline alloy. The microstructure of the alloys was analyzed by scanning electron microscopy and the phase composition was identified by X-ray diffractometry. The melting characteristics were studied by differential thermal analysis under an Ar atmosphere. The mechanical features of the melt-spun and conventionally solidified alloys were tested by tensile-strength test and Vickers micro-hardness test. It was found that the final microstructure of the Al{sub 20}Cu{sub 12}Fe samples mainly depends on the cooling rate and Mg contents, which suggestsmore » that different cooling rates and Mg contents produce different microstructures and properties. The average grain sizes of the melt spun samples were about 100–300 nm at 35 m/s. The nanosize, dispersed, different shaped quasicrystal particles possessed a remarkable effect to the mechanical characteristics of the rapidly solidified ribbons. The microhardness values of the melt spun samples were approximately 18% higher than those of the conventionally counterparts. - Highlights: •Quasicrystal-creating materials have high potential for applications. •Different shaped nanosize quasicrystal particles were observed. •The addition of Mg has an important impact on the mechanical properties. •H{sub V} values of the MS0, MS3 and MS5 samples at 35 m/s were 8.56, 8.66 and 8.80 GPa. •The volume fraction of IQC increases with increasing cooling rates.« less
40 CFR 81.112 - Charleston Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Quality Control Regions § 81.112 Charleston Intrastate Air Quality Control Region. The Charleston Intrastate Air Quality Control Region (South Carolina) consists of the territorial area encompassed by the... Quality Control Region: Region 1. 81.107Greenwood Intrastate Air Quality Control Region: Region 2. 81...
40 CFR 81.112 - Charleston Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Quality Control Regions § 81.112 Charleston Intrastate Air Quality Control Region. The Charleston Intrastate Air Quality Control Region (South Carolina) consists of the territorial area encompassed by the... Quality Control Region: Region 1. 81.107Greenwood Intrastate Air Quality Control Region: Region 2. 81...
40 CFR 81.88 - Billings Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Quality Control Regions § 81.88 Billings Intrastate Air Quality Control Region. The Metropolitan Billings Intrastate Air Quality Control Region (Montana) has been renamed the Billings Intrastate Air Quality Control... to by Montana authorities as follows: Sec. 481.168Great Falls Intrastate Air Quality Control Region...
40 CFR 81.88 - Billings Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Quality Control Regions § 81.88 Billings Intrastate Air Quality Control Region. The Metropolitan Billings Intrastate Air Quality Control Region (Montana) has been renamed the Billings Intrastate Air Quality Control... to by Montana authorities as follows: Sec. 481.168Great Falls Intrastate Air Quality Control Region...
Quality Control for Interviews to Obtain Dietary Recalls from Children for Research Studies
SHAFFER, NICOLE M.; THOMPSON, WILLIAM O.; BAGLIO, MICHELLE L.; GUINN, CAROLINE H.; FRYE, FRANCESCA H. A.
2005-01-01
Quality control is an important aspect of a study because the quality of data collected provides a foundation for the conclusions drawn from the study. For studies that include interviews, establishing quality control for interviews is critical in ascertaining whether interviews are conducted according to protocol. Despite the importance of quality control for interviews, few studies adequately document the quality control procedures used during data collection. This article reviews quality control for interviews and describes methods and results of quality control for interviews from two of our studies regarding the accuracy of children's dietary recalls; the focus is on quality control regarding interviewer performance during the interview, and examples are provided from studies with children. For our two studies, every interview was audio recorded and transcribed. The audio recording and typed transcript from one interview conducted by each research dietitian either weekly or daily were randomly selected and reviewed by another research dietitian, who completed a standardized quality control for interviews checklist. Major strengths of the methods of quality control for interviews in our two studies include: (a) interviews obtained for data collection were randomly selected for quality control for interviews, and (b) quality control for interviews was assessed on a regular basis throughout data collection. The methods of quality control for interviews described may help researchers design appropriate methods of quality control for interviews for future studies. PMID:15389417
Li, Hong-Jiao; He, Li-Yun; Liu, Zhi-Shun; Sun, Ya-Nan; Yan, Shi-Yan; Liu, Jia; Zhao, Ye; Liu, Bao-Yan
2014-02-01
To effectively guarantee quality of randomized controlld trial (RCT) of acupuncture and develop reasonable content and checklist of on-site quality control, influencing factors on quality of acupuncture RCT are analyzed and scientificity of quality control content and feasibility of on-site manipulation are put into overall consideration. Based on content and checklist of on-site quality control in National 11th Five-Year Plan Project Optimization of Comprehensive Treatment Plan for TCM in Prevention and Treatment of Serious Disease and Clinical Assessment on Generic Technology and Quality Control Research, it is proposed that on-site quality control of acupuncture RCT should be conducted with PICOST (patient, intervention, comparison, out come, site and time) as core, especially on quality control of interveners' skills and outcome assessment of blinding, and checklist of on-site quality control is developed to provide references for undertaking groups of the project.
21 CFR 111.105 - What must quality control personnel do?
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 2 2011-04-01 2011-04-01 false What must quality control personnel do? 111.105... for Quality Control § 111.105 What must quality control personnel do? Quality control personnel must... manufacturing record. To do so, quality control personnel must perform operations that include: (a) Approving or...
Total Quality Management Implementation Strategy: Directorate of Quality Assurance
1989-05-01
Total Quality Control Harrington, H. James The Improvement Process Imai, Masaaki Kaizen Ishikawa , Kaoru What is Total Quality Control Ishikawa ... Kaoru Statistical Quality Control Juran, J. M. Managerial Breakthrough Juran, J. M. Quality Control Handbook Mizuno, Ed Managing for Quality Improvements
30 CFR 28.31 - Quality control plans; contents.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Quality control plans; contents. 28.31 Section... PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control § 28.31 Quality control plans; contents. (a) Each quality control plan shall contain provisions for the management of quality, including: (1...
Principles and Practices for Quality Assurance and Quality Control
Jones, Berwyn E.
1999-01-01
Quality assurance and quality control are vital parts of highway runoff water-quality monitoring projects. To be effective, project quality assurance must address all aspects of the project, including project management responsibilities and resources, data quality objectives, sampling and analysis plans, data-collection protocols, data quality-control plans, data-assessment procedures and requirements, and project outputs. Quality control ensures that the data quality objectives are achieved as planned. The historical development and current state of the art of quality assurance and quality control concepts described in this report can be applied to evaluation of data from prior projects.
21 CFR 111.105 - What must quality control personnel do?
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What must quality control personnel do? 111.105..., LABELING, OR HOLDING OPERATIONS FOR DIETARY SUPPLEMENTS Production and Process Control System: Requirements for Quality Control § 111.105 What must quality control personnel do? Quality control personnel must...
40 CFR 81.77 - Puerto Rico Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Puerto Rico Air Quality Control Region... PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.77 Puerto Rico Air Quality Control Region. The Puerto Rico Air Quality Control Region...
40 CFR 81.77 - Puerto Rico Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Puerto Rico Air Quality Control Region... PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.77 Puerto Rico Air Quality Control Region. The Puerto Rico Air Quality Control Region...
40 CFR 81.77 - Puerto Rico Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Puerto Rico Air Quality Control Region... PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.77 Puerto Rico Air Quality Control Region. The Puerto Rico Air Quality Control Region...
40 CFR 81.77 - Puerto Rico Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Puerto Rico Air Quality Control Region... PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.77 Puerto Rico Air Quality Control Region. The Puerto Rico Air Quality Control Region...
40 CFR 81.89 - Metropolitan Cheyenne Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Quality Control Region. 81.89 Section 81.89 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.89 Metropolitan Cheyenne Intrastate Air Quality Control Region. The Metropolitan Cheyenne Intrastate Air Quality Control Region (Wyoming) consists of the territorial area...
40 CFR 81.101 - Metropolitan Dubuque Interstate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Quality Control Region. 81.101 Section 81.101 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.101 Metropolitan Dubuque Interstate Air Quality Control Region. The Metropolitan Dubuque Interstate Air Quality Control Region (Illinois-Iowa-Wisconsin) consists of the...
40 CFR 81.106 - Greenville-Spartanburg Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Quality Control Region. 81.106 Section 81.106 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.106 Greenville-Spartanburg Intrastate Air Quality Control Region. The Greenville-Spartanburg Intrastate Air Quality Control Region (South Carolina) consists of the territorial...
40 CFR 81.101 - Metropolitan Dubuque Interstate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Quality Control Region. 81.101 Section 81.101 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.101 Metropolitan Dubuque Interstate Air Quality Control Region. The Metropolitan Dubuque Interstate Air Quality Control Region (Illinois-Iowa-Wisconsin) consists of the...
40 CFR 81.106 - Greenville-Spartanburg Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Quality Control Region. 81.106 Section 81.106 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.106 Greenville-Spartanburg Intrastate Air Quality Control Region. The Greenville-Spartanburg Intrastate Air Quality Control Region (South Carolina) consists of the territorial...
40 CFR 81.89 - Metropolitan Cheyenne Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Quality Control Region. 81.89 Section 81.89 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.89 Metropolitan Cheyenne Intrastate Air Quality Control Region. The Metropolitan Cheyenne Intrastate Air Quality Control Region (Wyoming) consists of the territorial area...
40 CFR 81.62 - Northeast Mississippi Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Quality Control Region. 81.62 Section 81.62 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.62 Northeast Mississippi Intrastate Air Quality Control Region. The Alabama-Mississippi-Tennessee Interstate Air Quality Control Region has been renamed the Northeast...
40 CFR 81.78 - Metropolitan Portland Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Quality Control Region. 81.78 Section 81.78 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.78 Metropolitan Portland Intrastate Air Quality Control Region. The Metropolitan Portland Intrastate Air Quality Control Region (Maine) consists of the territorial area...
40 CFR 81.118 - Southwest Missouri Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Quality Control Region. 81.118 Section 81.118 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.118 Southwest Missouri Intrastate Air Quality Control Region. The Southwest Missouri Intrastate Air Quality Control Region consists of the territorial area encompassed by the...
40 CFR 81.87 - Metropolitan Boise Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Quality Control Region. 81.87 Section 81.87 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.87 Metropolitan Boise Intrastate Air Quality Control Region. The Metropolitan Boise Intrastate Air Quality Control Region (Idaho) consists of the territorial area encompassed...
40 CFR 81.116 - Northern Missouri Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Quality Control Region. 81.116 Section 81.116 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.116 Northern Missouri Intrastate Air Quality Control Region. The Northern Missouri Intrastate Air Quality Control Region consists of the territorial area encompassed by the...
40 CFR 81.97 - Southwest Florida Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Quality Control Region. 81.97 Section 81.97 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.97 Southwest Florida Intrastate Air Quality Control Region. The Southwest Florida Intrastate Air Quality Control Region consists of the territorial area encompassed by the...
40 CFR 81.104 - Central Pennsylvania Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Quality Control Region. 81.104 Section 81.104 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.104 Central Pennsylvania Intrastate Air Quality Control Region. The Central Pennsylvania Intrastate Air Quality Control Region consists of the territorial area encompassed by...
40 CFR 81.120 - Middle Tennessee Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Quality Control Region. 81.120 Section 81.120 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.120 Middle Tennessee Intrastate Air Quality Control Region. The Middle Tennessee Intrastate Air Quality Control Region consists of the territorial area encompassed by...
40 CFR 81.117 - Southeast Missouri Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Quality Control Region. 81.117 Section 81.117 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.117 Southeast Missouri Intrastate Air Quality Control Region. The Southeast Missouri Intrastate Air Quality Control Region consists of the territorial area encompassed by the...
40 CFR 81.75 - Metropolitan Charlotte Interstate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Quality Control Region. 81.75 Section 81.75 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.75 Metropolitan Charlotte Interstate Air Quality Control Region. The Metropolitan Charlotte Interstate Air Quality Control Region (North Carolina-South Carolina) has been revised...
40 CFR 81.98 - Burlington-Keokuk Interstate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Quality Control Region. 81.98 Section 81.98 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.98 Burlington-Keokuk Interstate Air Quality Control Region. The Burlington-Keokuk Interstate Air Quality Control Region (Illinois-Iowa) is revised to consist of the...
40 CFR 81.79 - Northeastern Oklahoma Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Quality Control Region. 81.79 Section 81.79 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.79 Northeastern Oklahoma Intrastate Air Quality Control Region. The Metropolitan Tulsa Intrastate Air Quality Control Region has been renamed the Northeastern Oklahoma Intrastate...
40 CFR 81.118 - Southwest Missouri Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Quality Control Region. 81.118 Section 81.118 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.118 Southwest Missouri Intrastate Air Quality Control Region. The Southwest Missouri Intrastate Air Quality Control Region consists of the territorial area encompassed by the...
40 CFR 81.119 - Western Tennessee Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Quality Control Region. 81.119 Section 81.119 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.119 Western Tennessee Intrastate Air Quality Control Region. The Western Tennessee Intrastate Air Quality Control Region consists of the territorial area encompassed by...
40 CFR 81.115 - Northwest Nevada Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Quality Control Region. 81.115 Section 81.115 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.115 Northwest Nevada Intrastate Air Quality Control Region. The Northwest Nevada Intrastate Air Quality Control Region consists of the territorial area encompassed by the...
40 CFR 81.116 - Northern Missouri Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Quality Control Region. 81.116 Section 81.116 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.116 Northern Missouri Intrastate Air Quality Control Region. The Northern Missouri Intrastate Air Quality Control Region consists of the territorial area encompassed by the...
40 CFR 81.104 - Central Pennsylvania Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Quality Control Region. 81.104 Section 81.104 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.104 Central Pennsylvania Intrastate Air Quality Control Region. The Central Pennsylvania Intrastate Air Quality Control Region consists of the territorial area encompassed by...
40 CFR 81.87 - Metropolitan Boise Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Quality Control Region. 81.87 Section 81.87 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.87 Metropolitan Boise Intrastate Air Quality Control Region. The Metropolitan Boise Intrastate Air Quality Control Region (Idaho) consists of the territorial area encompassed...
40 CFR 81.123 - Southeastern Oklahoma Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Quality Control Region. 81.123 Section 81.123 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.123 Southeastern Oklahoma Intrastate Air Quality Control Region. The Southeastern Oklahoma Intrastate Air Quality Control Region consists of the territorial area encompassed by the...
40 CFR 81.79 - Northeastern Oklahoma Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Quality Control Region. 81.79 Section 81.79 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.79 Northeastern Oklahoma Intrastate Air Quality Control Region. The Metropolitan Tulsa Intrastate Air Quality Control Region has been renamed the Northeastern Oklahoma Intrastate...
40 CFR 81.67 - Lake Michigan Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Quality Control Regions § 81.67 Lake Michigan Intrastate Air Quality Control Region. The Menominee-Escanaba (Michigan)-Marinette (Wisconsin) Interstate Air Quality Control Region has been renamed the Lake Michigan Intrastate Air Quality Control Region (Wisconsin) and revised to consist of the territorial area...
40 CFR 81.115 - Northwest Nevada Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Quality Control Region. 81.115 Section 81.115 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.115 Northwest Nevada Intrastate Air Quality Control Region. The Northwest Nevada Intrastate Air Quality Control Region consists of the territorial area encompassed by the...
40 CFR 81.97 - Southwest Florida Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Quality Control Region. 81.97 Section 81.97 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.97 Southwest Florida Intrastate Air Quality Control Region. The Southwest Florida Intrastate Air Quality Control Region consists of the territorial area encompassed by the...
40 CFR 81.117 - Southeast Missouri Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Quality Control Region. 81.117 Section 81.117 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.117 Southeast Missouri Intrastate Air Quality Control Region. The Southeast Missouri Intrastate Air Quality Control Region consists of the territorial area encompassed by the...
40 CFR 81.122 - Mississippi Delta Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Quality Control Region. 81.122 Section 81.122 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.122 Mississippi Delta Intrastate Air Quality Control Region. The Mississippi Delta Intrastate Air Quality Control Region consists of the territorial area encompassed by the...
40 CFR 81.98 - Burlington-Keokuk Interstate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Quality Control Region. 81.98 Section 81.98 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.98 Burlington-Keokuk Interstate Air Quality Control Region. The Burlington-Keokuk Interstate Air Quality Control Region (Illinois-Iowa) is revised to consist of the...
42 CFR 84.41 - Quality control plans; contents.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 42 Public Health 1 2014-10-01 2014-10-01 false Quality control plans; contents. 84.41 Section 84... AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Quality Control § 84.41 Quality control plans; contents. (a) Each quality control plan shall contain provisions for the...
42 CFR 84.41 - Quality control plans; contents.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 42 Public Health 1 2012-10-01 2012-10-01 false Quality control plans; contents. 84.41 Section 84... AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Quality Control § 84.41 Quality control plans; contents. (a) Each quality control plan shall contain provisions for the...
42 CFR 84.41 - Quality control plans; contents.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 42 Public Health 1 2013-10-01 2013-10-01 false Quality control plans; contents. 84.41 Section 84... AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Quality Control § 84.41 Quality control plans; contents. (a) Each quality control plan shall contain provisions for the...
42 CFR 84.41 - Quality control plans; contents.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 42 Public Health 1 2010-10-01 2010-10-01 false Quality control plans; contents. 84.41 Section 84... AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Quality Control § 84.41 Quality control plans; contents. (a) Each quality control plan shall contain provisions for the...
42 CFR 84.41 - Quality control plans; contents.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 42 Public Health 1 2011-10-01 2011-10-01 false Quality control plans; contents. 84.41 Section 84... AND HEALTH RESEARCH AND RELATED ACTIVITIES APPROVAL OF RESPIRATORY PROTECTIVE DEVICES Quality Control § 84.41 Quality control plans; contents. (a) Each quality control plan shall contain provisions for the...
20 CFR 602.41 - Proper expenditure of Quality Control granted funds.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Proper expenditure of Quality Control granted... LABOR QUALITY CONTROL IN THE FEDERAL-STATE UNEMPLOYMENT INSURANCE SYSTEM Quality Control Grants to States § 602.41 Proper expenditure of Quality Control granted funds. The Secretary may, after reasonable...
30 CFR 28.32 - Proposed quality control plans; approval by MSHA.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Proposed quality control plans; approval by...-CIRCUIT PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control § 28.32 Proposed quality control plans; approval by MSHA. (a) Each proposed quality control plan submitted in accordance with this...
20 CFR 602.41 - Proper expenditure of Quality Control granted funds.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Proper expenditure of Quality Control granted... LABOR QUALITY CONTROL IN THE FEDERAL-STATE UNEMPLOYMENT INSURANCE SYSTEM Quality Control Grants to States § 602.41 Proper expenditure of Quality Control granted funds. The Secretary may, after reasonable...
30 CFR 28.30 - Quality control plans; filing requirements.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Quality control plans; filing requirements. 28... PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control § 28.30 Quality control plans; filing... part, each applicant shall file with MSHA a proposed quality control plan which shall be designed to...
30 CFR 28.30 - Quality control plans; filing requirements.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Quality control plans; filing requirements. 28... PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control § 28.30 Quality control plans; filing... part, each applicant shall file with MSHA a proposed quality control plan which shall be designed to...
30 CFR 28.30 - Quality control plans; filing requirements.
Code of Federal Regulations, 2013 CFR
2013-07-01
... PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control § 28.30 Quality control plans; filing... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Quality control plans; filing requirements. 28... part, each applicant shall file with MSHA a proposed quality control plan which shall be designed to...
30 CFR 28.32 - Proposed quality control plans; approval by MSHA.
Code of Federal Regulations, 2012 CFR
2012-07-01
...-CIRCUIT PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control § 28.32 Proposed quality control plans; approval by MSHA. (a) Each proposed quality control plan submitted in accordance with this... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Proposed quality control plans; approval by...
30 CFR 28.32 - Proposed quality control plans; approval by MSHA.
Code of Federal Regulations, 2013 CFR
2013-07-01
...-CIRCUIT PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control § 28.32 Proposed quality control plans; approval by MSHA. (a) Each proposed quality control plan submitted in accordance with this... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Proposed quality control plans; approval by...
30 CFR 28.30 - Quality control plans; filing requirements.
Code of Federal Regulations, 2012 CFR
2012-07-01
... PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control § 28.30 Quality control plans; filing... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Quality control plans; filing requirements. 28... part, each applicant shall file with MSHA a proposed quality control plan which shall be designed to...
30 CFR 28.30 - Quality control plans; filing requirements.
Code of Federal Regulations, 2014 CFR
2014-07-01
... PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control § 28.30 Quality control plans; filing... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Quality control plans; filing requirements. 28... part, each applicant shall file with MSHA a proposed quality control plan which shall be designed to...
30 CFR 28.32 - Proposed quality control plans; approval by MSHA.
Code of Federal Regulations, 2014 CFR
2014-07-01
...-CIRCUIT PROTECTION FOR TRAILING CABLES IN COAL MINES Quality Control § 28.32 Proposed quality control plans; approval by MSHA. (a) Each proposed quality control plan submitted in accordance with this... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Proposed quality control plans; approval by...
21 CFR 866.5910 - Quality control material for cystic fibrosis nucleic acid assays.
Code of Federal Regulations, 2013 CFR
2013-04-01
... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Quality control material for cystic fibrosis... Test Systems § 866.5910 Quality control material for cystic fibrosis nucleic acid assays. (a) Identification. Quality control material for cystic fibrosis nucleic acid assays. A quality control material for...
21 CFR 866.5910 - Quality control material for cystic fibrosis nucleic acid assays.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Quality control material for cystic fibrosis... Test Systems § 866.5910 Quality control material for cystic fibrosis nucleic acid assays. (a) Identification. Quality control material for cystic fibrosis nucleic acid assays. A quality control material for...
21 CFR 866.5910 - Quality control material for cystic fibrosis nucleic acid assays.
Code of Federal Regulations, 2012 CFR
2012-04-01
... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Quality control material for cystic fibrosis... Test Systems § 866.5910 Quality control material for cystic fibrosis nucleic acid assays. (a) Identification. Quality control material for cystic fibrosis nucleic acid assays. A quality control material for...
21 CFR 866.5910 - Quality control material for cystic fibrosis nucleic acid assays.
Code of Federal Regulations, 2014 CFR
2014-04-01
... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Quality control material for cystic fibrosis... Test Systems § 866.5910 Quality control material for cystic fibrosis nucleic acid assays. (a) Identification. Quality control material for cystic fibrosis nucleic acid assays. A quality control material for...
21 CFR 211.22 - Responsibilities of quality control unit.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 4 2011-04-01 2011-04-01 false Responsibilities of quality control unit. 211.22... Personnel § 211.22 Responsibilities of quality control unit. (a) There shall be a quality control unit that... have been fully investigated. The quality control unit shall be responsible for approving or rejecting...
21 CFR 211.22 - Responsibilities of quality control unit.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Responsibilities of quality control unit. 211.22... Personnel § 211.22 Responsibilities of quality control unit. (a) There shall be a quality control unit that... have been fully investigated. The quality control unit shall be responsible for approving or rejecting...
40 CFR 81.99 - New Mexico Southern Border Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Designation of Air Quality Control Regions § 81.99 New Mexico Southern Border Intrastate Air Quality Control Region. The Arizona-New Mexico Southern Border Interstate Air Quality Control Region has been renamed the New Mexico Southern Border Intrastate Air Quality Control Region and has been revised to consist of...
40 CFR 81.76 - State of Hawaii Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 17 2011-07-01 2011-07-01 false State of Hawaii Air Quality Control... PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.76 State of Hawaii Air Quality Control Region. The State of Hawaii Air Quality...
40 CFR 81.76 - State of Hawaii Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 18 2012-07-01 2012-07-01 false State of Hawaii Air Quality Control... PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.76 State of Hawaii Air Quality Control Region. The State of Hawaii Air Quality...
40 CFR 81.76 - State of Hawaii Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 18 2013-07-01 2013-07-01 false State of Hawaii Air Quality Control... PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.76 State of Hawaii Air Quality Control Region. The State of Hawaii Air Quality...
40 CFR 81.76 - State of Hawaii Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false State of Hawaii Air Quality Control... PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.76 State of Hawaii Air Quality Control Region. The State of Hawaii Air Quality...
A system framework of inter-enterprise machining quality control based on fractal theory
NASA Astrophysics Data System (ADS)
Zhao, Liping; Qin, Yongtao; Yao, Yiyong; Yan, Peng
2014-03-01
In order to meet the quality control requirement of dynamic and complicated product machining processes among enterprises, a system framework of inter-enterprise machining quality control based on fractal was proposed. In this system framework, the fractal-specific characteristic of inter-enterprise machining quality control function was analysed, and the model of inter-enterprise machining quality control was constructed by the nature of fractal structures. Furthermore, the goal-driven strategy of inter-enterprise quality control and the dynamic organisation strategy of inter-enterprise quality improvement were constructed by the characteristic analysis on this model. In addition, the architecture of inter-enterprise machining quality control based on fractal was established by means of Web service. Finally, a case study for application was presented. The result showed that the proposed method was available, and could provide guidance for quality control and support for product reliability in inter-enterprise machining processes.
Yu, Wen-Kang; Dong, Ling; Pei, Wen-Xuan; Sun, Zhi-Rong; Dai, Jun-Dong; Wang, Yun
2017-12-01
The whole process quality control and management of traditional Chinese medicine (TCM) decoction pieces is a system engineering, involving the base environment, seeds and seedlings, harvesting, processing and other multiple steps, so the accurate identification of factors in TCM production process that may induce the quality risk, as well as reasonable quality control measures are very important. At present, the concept of quality risk is mainly concentrated in the aspects of management and regulations, etc. There is no comprehensive analysis on possible risks in the quality control process of TCM decoction pieces, or analysis summary of effective quality control schemes. A whole process quality control and management system for TCM decoction pieces based on TCM quality tree was proposed in this study. This system effectively combined the process analysis method of TCM quality tree with the quality risk management, and can help managers to make real-time decisions while realizing the whole process quality control of TCM. By providing personalized web interface, this system can realize user-oriented information feedback, and was convenient for users to predict, evaluate and control the quality of TCM. In the application process, the whole process quality control and management system of the TCM decoction pieces can identify the related quality factors such as base environment, cultivation and pieces processing, extend and modify the existing scientific workflow according to their own production conditions, and provide different enterprises with their own quality systems, to achieve the personalized service. As a new quality management model, this paper can provide reference for improving the quality of Chinese medicine production and quality standardization. Copyright© by the Chinese Pharmaceutical Association.
40 CFR 81.16 - Metropolitan Denver Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.16 Metropolitan Denver Intrastate Air Quality Control Region. The Metropolitan Denver Intrastate Air Quality Control Region (Colorado) consists of the territorial area...
40 CFR 81.62 - Northeast Mississippi Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.62 Northeast Mississippi Intrastate Air Quality Control Region. The Alabama-Mississippi-Tennessee Interstate Air Quality Control Region has been renamed the Northeast...
40 CFR 81.16 - Metropolitan Denver Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.16 Metropolitan Denver Intrastate Air Quality Control Region. The Metropolitan Denver Intrastate Air Quality Control Region (Colorado) consists of the territorial area...
40 CFR 81.31 - Metropolitan Providence Interstate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.31 Metropolitan Providence Interstate Air Quality Control Region. The Metropolitan Providence Interstate Air Quality Control Region (Rhode Island-Massachusetts) consists of the...
40 CFR 81.16 - Metropolitan Denver Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.16 Metropolitan Denver Intrastate Air Quality Control Region. The Metropolitan Denver Intrastate Air Quality Control Region (Colorado) consists of the territorial area...
40 CFR 81.30 - Southeastern Wisconsin Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.30 Southeastern Wisconsin Intrastate Air Quality Control Region. The Metropolitan Milwaukee Intrastate Air Quality Control Region (Wisconsin) has been renamed the Southeastern...
40 CFR 81.31 - Metropolitan Providence Interstate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.31 Metropolitan Providence Interstate Air Quality Control Region. The Metropolitan Providence Interstate Air Quality Control Region (Rhode Island-Massachusetts) consists of the...
40 CFR 81.62 - Northeast Mississippi Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.62 Northeast Mississippi Intrastate Air Quality Control Region. The Alabama-Mississippi-Tennessee Interstate Air Quality Control Region has been renamed the Northeast...
40 CFR 81.28 - Metropolitan Baltimore Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.28 Metropolitan Baltimore Intrastate Air Quality Control Region. The Metropolitan Baltimore Intrastate Air Quality Control Region (Maryland) consists of the territorial area...
40 CFR 81.78 - Metropolitan Portland Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.78 Metropolitan Portland Intrastate Air Quality Control Region. The Metropolitan Portland Intrastate Air Quality Control Region (Maine) consists of the territorial area...
40 CFR 81.78 - Metropolitan Portland Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.78 Metropolitan Portland Intrastate Air Quality Control Region. The Metropolitan Portland Intrastate Air Quality Control Region (Maine) consists of the territorial area...
40 CFR 81.28 - Metropolitan Baltimore Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.28 Metropolitan Baltimore Intrastate Air Quality Control Region. The Metropolitan Baltimore Intrastate Air Quality Control Region (Maryland) consists of the territorial area...
40 CFR 81.62 - Northeast Mississippi Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.62 Northeast Mississippi Intrastate Air Quality Control Region. The Alabama-Mississippi-Tennessee Interstate Air Quality Control Region has been renamed the Northeast...
40 CFR 81.28 - Metropolitan Baltimore Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.28 Metropolitan Baltimore Intrastate Air Quality Control Region. The Metropolitan Baltimore Intrastate Air Quality Control Region (Maryland) consists of the territorial area...
40 CFR 81.30 - Southeastern Wisconsin Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.30 Southeastern Wisconsin Intrastate Air Quality Control Region. The Metropolitan Milwaukee Intrastate Air Quality Control Region (Wisconsin) has been renamed the Southeastern...
40 CFR 81.29 - Metropolitan Indianapolis Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... Air Quality Control Region. 81.29 Section 81.29 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.29 Metropolitan Indianapolis Intrastate Air Quality Control...
40 CFR 81.31 - Metropolitan Providence Interstate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.31 Metropolitan Providence Interstate Air Quality Control Region. The Metropolitan Providence Interstate Air Quality Control Region (Rhode Island-Massachusetts) consists of the...
40 CFR 81.29 - Metropolitan Indianapolis Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Air Quality Control Region. 81.29 Section 81.29 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.29 Metropolitan Indianapolis Intrastate Air Quality Control...
40 CFR 81.44 - Metropolitan Memphis Interstate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.44 Metropolitan Memphis Interstate Air Quality Control Region. The Metropolitan Memphis Interstate Air Quality Control Region (Arkansas-Mississippi-Tennessee) consists of the...
40 CFR 81.30 - Southeastern Wisconsin Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.30 Southeastern Wisconsin Intrastate Air Quality Control Region. The Metropolitan Milwaukee Intrastate Air Quality Control Region (Wisconsin) has been renamed the Southeastern...
40 CFR 81.30 - Southeastern Wisconsin Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.30 Southeastern Wisconsin Intrastate Air Quality Control Region. The Metropolitan Milwaukee Intrastate Air Quality Control Region (Wisconsin) has been renamed the Southeastern...
40 CFR 81.28 - Metropolitan Baltimore Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.28 Metropolitan Baltimore Intrastate Air Quality Control Region. The Metropolitan Baltimore Intrastate Air Quality Control Region (Maryland) consists of the territorial area...
40 CFR 81.29 - Metropolitan Indianapolis Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... Air Quality Control Region. 81.29 Section 81.29 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.29 Metropolitan Indianapolis Intrastate Air Quality Control...
40 CFR 81.19 - Metropolitan Boston Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.19 Metropolitan Boston Intrastate Air Quality Control Region. The Metropolitan Boston Intrastate Air Quality Control Region (Massachusetts) consists of the territorial area...
40 CFR 81.19 - Metropolitan Boston Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.19 Metropolitan Boston Intrastate Air Quality Control Region. The Metropolitan Boston Intrastate Air Quality Control Region (Massachusetts) consists of the territorial area...
40 CFR 81.44 - Metropolitan Memphis Interstate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.44 Metropolitan Memphis Interstate Air Quality Control Region. The Metropolitan Memphis Interstate Air Quality Control Region (Arkansas-Mississippi-Tennessee) consists of the...
40 CFR 81.16 - Metropolitan Denver Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.16 Metropolitan Denver Intrastate Air Quality Control Region. The Metropolitan Denver Intrastate Air Quality Control Region (Colorado) consists of the territorial area...
40 CFR 81.19 - Metropolitan Boston Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.19 Metropolitan Boston Intrastate Air Quality Control Region. The Metropolitan Boston Intrastate Air Quality Control Region (Massachusetts) consists of the territorial area...
40 CFR 81.19 - Metropolitan Boston Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.19 Metropolitan Boston Intrastate Air Quality Control Region. The Metropolitan Boston Intrastate Air Quality Control Region (Massachusetts) consists of the territorial area...
40 CFR 81.29 - Metropolitan Indianapolis Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... Air Quality Control Region. 81.29 Section 81.29 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.29 Metropolitan Indianapolis Intrastate Air Quality Control...
40 CFR 81.44 - Metropolitan Memphis Interstate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.44 Metropolitan Memphis Interstate Air Quality Control Region. The Metropolitan Memphis Interstate Air Quality Control Region (Arkansas-Mississippi-Tennessee) consists of the...
40 CFR 81.31 - Metropolitan Providence Interstate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.31 Metropolitan Providence Interstate Air Quality Control Region. The Metropolitan Providence Interstate Air Quality Control Region (Rhode Island-Massachusetts) consists of the...
40 CFR 81.44 - Metropolitan Memphis Interstate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.44 Metropolitan Memphis Interstate Air Quality Control Region. The Metropolitan Memphis Interstate Air Quality Control Region (Arkansas-Mississippi-Tennessee) consists of the...
40 CFR 81.44 - Metropolitan Memphis Interstate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.44 Metropolitan Memphis Interstate Air Quality Control Region. The Metropolitan Memphis Interstate Air Quality Control Region (Arkansas-Mississippi-Tennessee) consists of the...
40 CFR 81.16 - Metropolitan Denver Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.16 Metropolitan Denver Intrastate Air Quality Control Region. The Metropolitan Denver Intrastate Air Quality Control Region (Colorado) consists of the territorial area...
40 CFR 81.28 - Metropolitan Baltimore Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.28 Metropolitan Baltimore Intrastate Air Quality Control Region. The Metropolitan Baltimore Intrastate Air Quality Control Region (Maryland) consists of the territorial area...
40 CFR 81.30 - Southeastern Wisconsin Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.30 Southeastern Wisconsin Intrastate Air Quality Control Region. The Metropolitan Milwaukee Intrastate Air Quality Control Region (Wisconsin) has been renamed the Southeastern...
40 CFR 81.19 - Metropolitan Boston Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.19 Metropolitan Boston Intrastate Air Quality Control Region. The Metropolitan Boston Intrastate Air Quality Control Region (Massachusetts) consists of the territorial area...
40 CFR 81.29 - Metropolitan Indianapolis Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Air Quality Control Region. 81.29 Section 81.29 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.29 Metropolitan Indianapolis Intrastate Air Quality Control...
40 CFR 81.78 - Metropolitan Portland Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.78 Metropolitan Portland Intrastate Air Quality Control Region. The Metropolitan Portland Intrastate Air Quality Control Region (Maine) consists of the territorial area...
40 CFR 81.62 - Northeast Mississippi Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.62 Northeast Mississippi Intrastate Air Quality Control Region. The Alabama-Mississippi-Tennessee Interstate Air Quality Control Region has been renamed the Northeast...
40 CFR 81.31 - Metropolitan Providence Interstate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.31 Metropolitan Providence Interstate Air Quality Control Region. The Metropolitan Providence Interstate Air Quality Control Region (Rhode Island-Massachusetts) consists of the...
40 CFR 81.107 - Greenwood Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Quality Control Regions § 81.107 Greenwood Intrastate Air Quality Control Region. The Greenwood Intrastate Air Quality Control Region (South Carolina) consists of the territorial area encompassed by the... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Greenwood Intrastate Air Quality...
40 CFR 81.108 - Columbia Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Quality Control Regions § 81.108 Columbia Intrastate Air Quality Control Region. The Columbia Intrastate Air Quality Control Region (South Carolina) consists of the territorial area encompassed by the... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Columbia Intrastate Air Quality...
40 CFR 81.108 - Columbia Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Quality Control Regions § 81.108 Columbia Intrastate Air Quality Control Region. The Columbia Intrastate Air Quality Control Region (South Carolina) consists of the territorial area encompassed by the... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Columbia Intrastate Air Quality...
40 CFR 81.111 - Georgetown Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Quality Control Regions § 81.111 Georgetown Intrastate Air Quality Control Region. The Georgetown Intrastate Air Quality Control Region (South Carolina) consists of the territorial area encompassed by the... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Georgetown Intrastate Air Quality...
40 CFR 81.109 - Florence Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Quality Control Regions § 81.109 Florence Intrastate Air Quality Control Region. The Florence Intrastate Air Quality Control Region (South Carolina) consists of the territorial area encompassed by the... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Florence Intrastate Air Quality...
40 CFR 81.111 - Georgetown Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Quality Control Regions § 81.111 Georgetown Intrastate Air Quality Control Region. The Georgetown Intrastate Air Quality Control Region (South Carolina) consists of the territorial area encompassed by the... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Georgetown Intrastate Air Quality...
40 CFR 81.109 - Florence Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Quality Control Regions § 81.109 Florence Intrastate Air Quality Control Region. The Florence Intrastate Air Quality Control Region (South Carolina) consists of the territorial area encompassed by the... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Florence Intrastate Air Quality...
40 CFR 81.107 - Greenwood Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Quality Control Regions § 81.107 Greenwood Intrastate Air Quality Control Region. The Greenwood Intrastate Air Quality Control Region (South Carolina) consists of the territorial area encompassed by the... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Greenwood Intrastate Air Quality...
40 CFR 81.90 - Androscoggin Valley Interstate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Quality Control Region. 81.90 Section 81.90 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.90 Androscoggin Valley Interstate Air Quality Control Region. The...
40 CFR 81.90 - Androscoggin Valley Interstate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Quality Control Region. 81.90 Section 81.90 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.90 Androscoggin Valley Interstate Air Quality Control Region. The...
40 CFR 81.75 - Metropolitan Charlotte Interstate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.75 Metropolitan Charlotte Interstate Air Quality Control Region. The Metropolitan Charlotte Interstate Air Quality Control Region (North Carolina-South Carolina) has been revised...
40 CFR 81.45 - Metropolitan Atlanta Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.45 Metropolitan Atlanta Intrastate Air Quality Control Region. The Metropolitan Atlanta Intrastate Air Quality Control Region (Georgia) has been revised to consist of the...
40 CFR 81.34 - Metropolitan Dayton Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.34 Metropolitan Dayton Intrastate Air Quality Control Region. The Metropolitan Dayton Intrastate Air Quality Control Region consists of the territorial area encompassed by the...
40 CFR 81.24 - Niagara Frontier Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.24 Niagara Frontier Intrastate Air Quality Control Region. The Niagara Frontier Intrastate Air Quality Control Region (New York) consists of the territorial area...
40 CFR 81.43 - Metropolitan Toledo Interstate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.43 Metropolitan Toledo Interstate Air Quality Control Region. The Metropolitan Toledo Interstate Air Quality Control Region (Ohio-Michigan) consists of the territorial area...
40 CFR 81.45 - Metropolitan Atlanta Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.45 Metropolitan Atlanta Intrastate Air Quality Control Region. The Metropolitan Atlanta Intrastate Air Quality Control Region (Georgia) has been revised to consist of the...
40 CFR 81.47 - Central Oklahoma Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.47 Central Oklahoma Intrastate Air Quality Control Region. The Metropolitan Oklahoma Intrastate Air Quality Control Region has been renamed the Central Oklahoma Intrastate...
40 CFR 81.41 - Metropolitan Birmingham Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.41 Metropolitan Birmingham Intrastate Air Quality Control Region. The Metropolitan Birmingham Intrastate Air Quality Control Region (Alabama) has been revised to consist of the...
40 CFR 81.34 - Metropolitan Dayton Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.34 Metropolitan Dayton Intrastate Air Quality Control Region. The Metropolitan Dayton Intrastate Air Quality Control Region consists of the territorial area encompassed by the...
40 CFR 81.41 - Metropolitan Birmingham Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.41 Metropolitan Birmingham Intrastate Air Quality Control Region. The Metropolitan Birmingham Intrastate Air Quality Control Region (Alabama) has been revised to consist of the...
40 CFR 81.20 - Metropolitan Cincinnati Interstate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.20 Metropolitan Cincinnati Interstate Air Quality Control Region. The Metropolitan Cincinnati Interstate Air Quality Control Region (Ohio-Kentucky-Indiana) is revised to consist of...
40 CFR 81.23 - Southwest Pennsylvania Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.23 Southwest Pennsylvania Intrastate Air Quality Control Region. The Southwest Pennsylvania Intrastate Air Quality Control Region is redesignated to consist of the territorial...
40 CFR 81.34 - Metropolitan Dayton Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.34 Metropolitan Dayton Intrastate Air Quality Control Region. The Metropolitan Dayton Intrastate Air Quality Control Region consists of the territorial area encompassed by the...
40 CFR 81.79 - Northeastern Oklahoma Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.79 Northeastern Oklahoma Intrastate Air Quality Control Region. The Metropolitan Tulsa Intrastate Air Quality Control Region has been renamed the Northeastern Oklahoma Intrastate...
40 CFR 81.59 - Cumberland-Keyser Interstate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.59 Cumberland-Keyser Interstate Air Quality Control Region. The Cumberland-Keyser Interstate Air Quality Control Region (Maryland-West Virginia) has been revised to consist...
40 CFR 81.49 - Southeast Florida Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.49 Southeast Florida Intrastate Air Quality Control Region. The Southeast Florida Intrastate Air Quality Control Region is redesignated to consist of the territorial area...
40 CFR 81.49 - Southeast Florida Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.49 Southeast Florida Intrastate Air Quality Control Region. The Southeast Florida Intrastate Air Quality Control Region is redesignated to consist of the territorial area...
40 CFR 81.41 - Metropolitan Birmingham Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.41 Metropolitan Birmingham Intrastate Air Quality Control Region. The Metropolitan Birmingham Intrastate Air Quality Control Region (Alabama) has been revised to consist of the...
40 CFR 81.41 - Metropolitan Birmingham Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.41 Metropolitan Birmingham Intrastate Air Quality Control Region. The Metropolitan Birmingham Intrastate Air Quality Control Region (Alabama) has been revised to consist of the...
40 CFR 81.34 - Metropolitan Dayton Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.34 Metropolitan Dayton Intrastate Air Quality Control Region. The Metropolitan Dayton Intrastate Air Quality Control Region consists of the territorial area encompassed by the...
40 CFR 81.43 - Metropolitan Toledo Interstate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.43 Metropolitan Toledo Interstate Air Quality Control Region. The Metropolitan Toledo Interstate Air Quality Control Region (Ohio-Michigan) consists of the territorial area...
40 CFR 81.24 - Niagara Frontier Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.24 Niagara Frontier Intrastate Air Quality Control Region. The Niagara Frontier Intrastate Air Quality Control Region (New York) consists of the territorial area...
40 CFR 81.47 - Central Oklahoma Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.47 Central Oklahoma Intrastate Air Quality Control Region. The Metropolitan Oklahoma Intrastate Air Quality Control Region has been renamed the Central Oklahoma Intrastate...
40 CFR 81.23 - Southwest Pennsylvania Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.23 Southwest Pennsylvania Intrastate Air Quality Control Region. The Southwest Pennsylvania Intrastate Air Quality Control Region is redesignated to consist of the territorial...
40 CFR 81.49 - Southeast Florida Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.49 Southeast Florida Intrastate Air Quality Control Region. The Southeast Florida Intrastate Air Quality Control Region is redesignated to consist of the territorial area...
40 CFR 81.45 - Metropolitan Atlanta Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.45 Metropolitan Atlanta Intrastate Air Quality Control Region. The Metropolitan Atlanta Intrastate Air Quality Control Region (Georgia) has been revised to consist of the...
40 CFR 81.47 - Central Oklahoma Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.47 Central Oklahoma Intrastate Air Quality Control Region. The Metropolitan Oklahoma Intrastate Air Quality Control Region has been renamed the Central Oklahoma Intrastate...
40 CFR 81.23 - Southwest Pennsylvania Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.23 Southwest Pennsylvania Intrastate Air Quality Control Region. The Southwest Pennsylvania Intrastate Air Quality Control Region is redesignated to consist of the territorial...
40 CFR 81.59 - Cumberland-Keyser Interstate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.59 Cumberland-Keyser Interstate Air Quality Control Region. The Cumberland-Keyser Interstate Air Quality Control Region (Maryland-West Virginia) has been revised to consist...
40 CFR 81.20 - Metropolitan Cincinnati Interstate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.20 Metropolitan Cincinnati Interstate Air Quality Control Region. The Metropolitan Cincinnati Interstate Air Quality Control Region (Ohio-Kentucky-Indiana) is revised to consist of...
40 CFR 81.43 - Metropolitan Toledo Interstate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.43 Metropolitan Toledo Interstate Air Quality Control Region. The Metropolitan Toledo Interstate Air Quality Control Region (Ohio-Michigan) consists of the territorial area...
40 CFR 81.24 - Niagara Frontier Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.24 Niagara Frontier Intrastate Air Quality Control Region. The Niagara Frontier Intrastate Air Quality Control Region (New York) consists of the territorial area...
40 CFR 81.20 - Metropolitan Cincinnati Interstate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.20 Metropolitan Cincinnati Interstate Air Quality Control Region. The Metropolitan Cincinnati Interstate Air Quality Control Region (Ohio-Kentucky-Indiana) is revised to consist of...
40 CFR 81.43 - Metropolitan Toledo Interstate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.43 Metropolitan Toledo Interstate Air Quality Control Region. The Metropolitan Toledo Interstate Air Quality Control Region (Ohio-Michigan) consists of the territorial area...
40 CFR 81.75 - Metropolitan Charlotte Interstate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.75 Metropolitan Charlotte Interstate Air Quality Control Region. The Metropolitan Charlotte Interstate Air Quality Control Region (North Carolina-South Carolina) has been revised...
40 CFR 81.14 - Metropolitan Chicago Interstate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.14 Metropolitan Chicago Interstate Air Quality Control Region. The Metropolitan Chicago Interstate Air Quality Control Region (Illinois-Indiana) is revised to consist of the...
40 CFR 81.14 - Metropolitan Chicago Interstate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.14 Metropolitan Chicago Interstate Air Quality Control Region. The Metropolitan Chicago Interstate Air Quality Control Region (Illinois-Indiana) is revised to consist of the...
40 CFR 81.24 - Niagara Frontier Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.24 Niagara Frontier Intrastate Air Quality Control Region. The Niagara Frontier Intrastate Air Quality Control Region (New York) consists of the territorial area...
40 CFR 81.49 - Southeast Florida Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.49 Southeast Florida Intrastate Air Quality Control Region. The Southeast Florida Intrastate Air Quality Control Region is redesignated to consist of the territorial area...
40 CFR 81.23 - Southwest Pennsylvania Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.23 Southwest Pennsylvania Intrastate Air Quality Control Region. The Southwest Pennsylvania Intrastate Air Quality Control Region is redesignated to consist of the territorial...
40 CFR 81.14 - Metropolitan Chicago Interstate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.14 Metropolitan Chicago Interstate Air Quality Control Region. The Metropolitan Chicago Interstate Air Quality Control Region (Illinois-Indiana) is revised to consist of the...
40 CFR 81.20 - Metropolitan Cincinnati Interstate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.20 Metropolitan Cincinnati Interstate Air Quality Control Region. The Metropolitan Cincinnati Interstate Air Quality Control Region (Ohio-Kentucky-Indiana) is revised to consist of...
40 CFR 81.59 - Cumberland-Keyser Interstate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.59 Cumberland-Keyser Interstate Air Quality Control Region. The Cumberland-Keyser Interstate Air Quality Control Region (Maryland-West Virginia) has been revised to consist...
40 CFR 81.14 - Metropolitan Chicago Interstate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.14 Metropolitan Chicago Interstate Air Quality Control Region. The Metropolitan Chicago Interstate Air Quality Control Region (Illinois-Indiana) is revised to consist of the...
40 CFR 81.45 - Metropolitan Atlanta Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.45 Metropolitan Atlanta Intrastate Air Quality Control Region. The Metropolitan Atlanta Intrastate Air Quality Control Region (Georgia) has been revised to consist of the...
40 CFR 81.59 - Cumberland-Keyser Interstate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.59 Cumberland-Keyser Interstate Air Quality Control Region. The Cumberland-Keyser Interstate Air Quality Control Region (Maryland-West Virginia) has been revised to consist...
40 CFR 81.87 - Metropolitan Boise Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.87 Metropolitan Boise Intrastate Air Quality Control Region. The Metropolitan Boise Intrastate Air Quality Control Region (Idaho) consists of the territorial area encompassed...
40 CFR 81.47 - Central Oklahoma Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.47 Central Oklahoma Intrastate Air Quality Control Region. The Metropolitan Oklahoma Intrastate Air Quality Control Region has been renamed the Central Oklahoma Intrastate...
40 CFR 81.75 - Metropolitan Charlotte Interstate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.75 Metropolitan Charlotte Interstate Air Quality Control Region. The Metropolitan Charlotte Interstate Air Quality Control Region (North Carolina-South Carolina) has been revised...
40 CFR 81.79 - Northeastern Oklahoma Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.79 Northeastern Oklahoma Intrastate Air Quality Control Region. The Metropolitan Tulsa Intrastate Air Quality Control Region has been renamed the Northeastern Oklahoma Intrastate...
40 CFR 81.43 - Metropolitan Toledo Interstate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.43 Metropolitan Toledo Interstate Air Quality Control Region. The Metropolitan Toledo Interstate Air Quality Control Region (Ohio-Michigan) consists of the territorial area...
40 CFR 81.49 - Southeast Florida Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.49 Southeast Florida Intrastate Air Quality Control Region. The Southeast Florida Intrastate Air Quality Control Region is redesignated to consist of the territorial area...
40 CFR 81.20 - Metropolitan Cincinnati Interstate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.20 Metropolitan Cincinnati Interstate Air Quality Control Region. The Metropolitan Cincinnati Interstate Air Quality Control Region (Ohio-Kentucky-Indiana) is revised to consist of...
40 CFR 81.75 - Metropolitan Charlotte Interstate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.75 Metropolitan Charlotte Interstate Air Quality Control Region. The Metropolitan Charlotte Interstate Air Quality Control Region (North Carolina-South Carolina) has been revised...
40 CFR 81.47 - Central Oklahoma Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.47 Central Oklahoma Intrastate Air Quality Control Region. The Metropolitan Oklahoma Intrastate Air Quality Control Region has been renamed the Central Oklahoma Intrastate...
40 CFR 81.24 - Niagara Frontier Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.24 Niagara Frontier Intrastate Air Quality Control Region. The Niagara Frontier Intrastate Air Quality Control Region (New York) consists of the territorial area...
40 CFR 81.23 - Southwest Pennsylvania Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.23 Southwest Pennsylvania Intrastate Air Quality Control Region. The Southwest Pennsylvania Intrastate Air Quality Control Region is redesignated to consist of the territorial...
40 CFR 81.59 - Cumberland-Keyser Interstate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.59 Cumberland-Keyser Interstate Air Quality Control Region. The Cumberland-Keyser Interstate Air Quality Control Region (Maryland-West Virginia) has been revised to consist...
40 CFR 81.14 - Metropolitan Chicago Interstate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.14 Metropolitan Chicago Interstate Air Quality Control Region. The Metropolitan Chicago Interstate Air Quality Control Region (Illinois-Indiana) is revised to consist of the...
40 CFR 81.45 - Metropolitan Atlanta Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.45 Metropolitan Atlanta Intrastate Air Quality Control Region. The Metropolitan Atlanta Intrastate Air Quality Control Region (Georgia) has been revised to consist of the...
40 CFR 81.41 - Metropolitan Birmingham Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.41 Metropolitan Birmingham Intrastate Air Quality Control Region. The Metropolitan Birmingham Intrastate Air Quality Control Region (Alabama) has been revised to consist of the...
40 CFR 81.34 - Metropolitan Dayton Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.34 Metropolitan Dayton Intrastate Air Quality Control Region. The Metropolitan Dayton Intrastate Air Quality Control Region consists of the territorial area encompassed by the...
40 CFR 51.359 - Quality control.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 2 2013-07-01 2013-07-01 false Quality control. 51.359 Section 51.359....359 Quality control. Quality control measures shall insure that emission testing equipment is calibrated and maintained properly, and that inspection, calibration records, and control charts are...
40 CFR 51.359 - Quality control.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 2 2010-07-01 2010-07-01 false Quality control. 51.359 Section 51.359....359 Quality control. Quality control measures shall insure that emission testing equipment is calibrated and maintained properly, and that inspection, calibration records, and control charts are...
40 CFR 51.359 - Quality control.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 2 2011-07-01 2011-07-01 false Quality control. 51.359 Section 51.359....359 Quality control. Quality control measures shall insure that emission testing equipment is calibrated and maintained properly, and that inspection, calibration records, and control charts are...
40 CFR 51.359 - Quality control.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 2 2012-07-01 2012-07-01 false Quality control. 51.359 Section 51.359....359 Quality control. Quality control measures shall insure that emission testing equipment is calibrated and maintained properly, and that inspection, calibration records, and control charts are...
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What quality control operations are required for equipment, instruments, and controls? 111.117 Section 111.117 Food and Drugs FOOD AND DRUG ADMINISTRATION... and Process Control System: Requirements for Quality Control § 111.117 What quality control operations...
Quality transitivity and traceability system of herbal medicine products based on quality markers.
Liu, Changxiao; Guo, De-An; Liu, Liang
2018-05-15
Due to a variety of factors to affect the herb quality, the existing quality management model is unable to evaluate the process control. The development of the concept of "quality marker" (Q-marker) lays basis for establishing an independent process quality control system for herbal products. To ensure the highest degree of safety, effectiveness and quality process control of herbal products, it is aimed to establish a quality transitivity and traceability system of quality and process control from raw materials to finished herbal products. Based on the key issues and challenges of quality assessment, the current status of quality and process controls from raw materials to herbal medicinal products listed in Pharmacopoeia were analyzed and the research models including discovery and identification of Q-markers, analysis and quality management of risk evaluation were designed. Authors introduced a few new technologies and methodologies, such as DNA barcoding, chromatographic technologies, fingerprint analysis, chemical markers, bio-responses, risk management and solution for quality process control. The quality and process control models for herbal medicinal products were proposed and the transitivity and traceability system from raw materials to the finished products was constructed to improve the herbal quality from the entire supply and production chain. The transitivity and traceability system has been established based on quality markers, especially on how to control the production process under Good Engineering Practices, as well as to implement the risk management for quality and process control in herbal medicine production. Copyright © 2018 Elsevier GmbH. All rights reserved.
Guidance for Efficient Small Animal Imaging Quality Control.
Osborne, Dustin R; Kuntner, Claudia; Berr, Stuart; Stout, David
2017-08-01
Routine quality control is a critical aspect of properly maintaining high-performance small animal imaging instrumentation. A robust quality control program helps produce more reliable data both for academic purposes and as proof of system performance for contract imaging work. For preclinical imaging laboratories, the combination of costs and available resources often limits their ability to produce efficient and effective quality control programs. This work presents a series of simplified quality control procedures that are accessible to a wide range of preclinical imaging laboratories. Our intent is to provide minimum guidelines for routine quality control that can assist preclinical imaging specialists in setting up an appropriate quality control program for their facility.
40 CFR 81.110 - Camden-Sumter Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Quality Control Regions § 81.110 Camden-Sumter Intrastate Air Quality Control Region. The Camden-Sumter Intrastate Air Quality Control Region (South Carolina) consists of the territorial area encompassed by the... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Camden-Sumter Intrastate Air Quality...
7 CFR 58.928 - Quality control tests.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 7 Agriculture 3 2011-01-01 2011-01-01 false Quality control tests. 58.928 Section 58.928... Procedures § 58.928 Quality control tests. All dairy products and other ingredients shall be subject to inspection for quality and condition throughout each processing operation. Quality control tests shall be...
7 CFR 58.335 - Quality control tests.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 7 Agriculture 3 2011-01-01 2011-01-01 false Quality control tests. 58.335 Section 58.335... Procedures § 58.335 Quality control tests. All milk, cream and related products are subject to inspection for quality and condition throughout each processing operation. Quality control tests shall be made on flow...
21 CFR 862.1660 - Quality control material (assayed and unassayed).
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Quality control material (assayed and unassayed... Test Systems § 862.1660 Quality control material (assayed and unassayed). (a) Identification. A quality... that may arise from reagent or analytical instrument variation. A quality control material (assayed and...
40 CFR 81.110 - Camden-Sumter Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Quality Control Regions § 81.110 Camden-Sumter Intrastate Air Quality Control Region. The Camden-Sumter Intrastate Air Quality Control Region (South Carolina) consists of the territorial area encompassed by the... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Camden-Sumter Intrastate Air Quality...
40 CFR 81.202 - Northwest Ohio Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Northwest Ohio Intrastate Air Quality... Quality Control Regions § 81.202 Northwest Ohio Intrastate Air Quality Control Region. The Northwest Ohio Intrastate Air Quality Control Region (Ohio) consists of the territorial area encompassed by the boundaries...
40 CFR 81.48 - Champlain Valley Interstate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.48 Champlain Valley Interstate Air Quality Control Region. The Champlain Valley Interstate Air Quality Control Region (Vermont-New York) has been revised to consist of the...
40 CFR 81.48 - Champlain Valley Interstate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.48 Champlain Valley Interstate Air Quality Control Region. The Champlain Valley Interstate Air Quality Control Region (Vermont-New York) has been revised to consist of the...
40 CFR 81.48 - Champlain Valley Interstate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.48 Champlain Valley Interstate Air Quality Control Region. The Champlain Valley Interstate Air Quality Control Region (Vermont-New York) has been revised to consist of the...
40 CFR 81.48 - Champlain Valley Interstate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.48 Champlain Valley Interstate Air Quality Control Region. The Champlain Valley Interstate Air Quality Control Region (Vermont-New York) has been revised to consist of the...
40 CFR 81.48 - Champlain Valley Interstate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.48 Champlain Valley Interstate Air Quality Control Region. The Champlain Valley Interstate Air Quality Control Region (Vermont-New York) has been revised to consist of the...
Cheng, Yi-Yu; Qian, Zhong-Zhi; Zhang, Bo-Li
2017-01-01
The current situation, bottleneck problems and severe challenges in quality control technology of Chinese Medicine (CM) are briefly described. It is presented to change the phenomenon related to the post-test as the main means and contempt for process control in drug regulation, reverse the situation of neglecting the development of process control and management technology for pharmaceutical manufacture and reconstruct the technological system for quality control of CM products. The regulation and technology system based on process control and management for controlling CM quality should be established to solve weighty realistic problems of CM industry from the root causes, including backwardness of quality control technology, weakness of quality risk control measures, poor reputation of product quality and so on. By this way, the obstacles from poor controllability of CM product quality could be broken. Concentrating on those difficult problems and weak links in the technical field of CM quality control, it is proposed to build CMC (Chemistry, Manufacturing and Controls) regulation for CM products with Chinese characteristics and promote the regulation international recognition as soon as possible. The CMC technical framework, which is clinical efficacy-oriented, manufacturing manner-centered and process control-focused, was designed. To address the clinical characteristics of traditional Chinese medicine (TCM) and the production feature of CM manufacture, it is suggested to establish quality control engineering for CM manufacturing by integrating pharmaceutical analysis, TCM chemistry, TCM pharmacology, pharmaceutical engineering, control engineering, management engineering and other disciplines. Further, a theoretical model of quality control engineering for CM manufacturing and the methodology of digital pharmaceutical engineering are proposed. A technology pathway for promoting CM standard and realizing the strategic goal of CM internationalization is elaborated. Copyright© by the Chinese Pharmaceutical Association.
40 CFR 75.21 - Quality assurance and quality control requirements.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 16 2010-07-01 2010-07-01 false Quality assurance and quality control... PROGRAMS (CONTINUED) CONTINUOUS EMISSION MONITORING Operation and Maintenance Requirements § 75.21 Quality assurance and quality control requirements. (a) Continuous emission monitoring systems. The owner or...
40 CFR 81.80 - Las Vegas Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Quality Control Regions § 81.80 Las Vegas Intrastate Air Quality Control Region. The Las Vegas Intrastate Air Quality Control Region (Nevada) has been revised to consist of the territorial area encompassed by... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Las Vegas Intrastate Air Quality...
40 CFR 81.95 - Central Florida Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Quality Control Regions § 81.95 Central Florida Intrastate Air Quality Control Region. The Central Florida Intrastate Air Quality Control Region consists of the territorial area encompassed by the boundaries of the... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Central Florida Intrastate Air Quality...
40 CFR 81.95 - Central Florida Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Quality Control Regions § 81.95 Central Florida Intrastate Air Quality Control Region. The Central Florida Intrastate Air Quality Control Region consists of the territorial area encompassed by the boundaries of the... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Central Florida Intrastate Air Quality...
40 CFR 81.80 - Las Vegas Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Quality Control Regions § 81.80 Las Vegas Intrastate Air Quality Control Region. The Las Vegas Intrastate Air Quality Control Region (Nevada) has been revised to consist of the territorial area encompassed by... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Las Vegas Intrastate Air Quality...
Li, Hong-jiao; He, Li-yun; Liu, Bao-yan
2015-06-01
The effective quality control in clinical practices is an effective guarantee for the authenticity and scientificity of the findings. The post-marketing reevaluation for traditional Chinese medicines (TCM) focuses on the efficacy, adverse reaction, combined medication and effective dose of drugs in the market by expanded clinical trials, and requires a larger sample size and a wider range of patients. Therefore, this increases the difficulty of quality control in clinical practices. With the experience in quality control in clinical practices for the post-marketing reevaluation for Kangbingdu oral for cold, researchers in this study reviewed the study purpose, project, scheme design and clinical practice process from an overall point of view, analyzed the study characteristics of the post-marketing reevaluation for TCMs and the quality control risks, designed the quality control contents with quality impacting factors, defined key review contents and summarized the precautions in clinical practices, with the aim to improve the efficiency of quality control of clinical practices. This study can provide reference to clinical units and quality control-related personnel in the post-marketing reevaluation for TCMs.
Federal Register 2010, 2011, 2012, 2013, 2014
2010-12-21
... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5380-N-50] Quality Control Requirements... information: Title of Proposal: Quality Control Requirements for Direct Endorsement Lenders. OMB Control... a result, DE lenders will be responsible for conducting quality control on TPO originations of FHA...
40 CFR 81.77 - Puerto Rico Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Puerto Rico Air Quality Control Region... Control Regions § 81.77 Puerto Rico Air Quality Control Region. The Puerto Rico Air Quality Control Region... delimited): The entire Commonwealth of Puerto Rico: Puerto Rico and surrounding islands, Vieques and...
21 CFR 111.135 - What quality control operations are required for product complaints?
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What quality control operations are required for... MANUFACTURING, PACKAGING, LABELING, OR HOLDING OPERATIONS FOR DIETARY SUPPLEMENTS Production and Process Control System: Requirements for Quality Control § 111.135 What quality control operations are required for...
21 CFR 111.65 - What are the requirements for quality control operations?
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What are the requirements for quality control... Process Control System § 111.65 What are the requirements for quality control operations? You must implement quality control operations in your manufacturing, packaging, labeling, and holding operations for...
Hoscheit, Larry P; Heng, Hock Gan; Lim, Chee Kin; Weng, Hsin-Yi
2018-05-01
Image quality in B-mode ultrasound is important as it reflects the diagnostic accuracy and diagnostic information provided during clinical scanning. Quality assurance programs for B-mode ultrasound systems/components are comprised of initial quality acceptance testing and subsequent regularly scheduled quality control testing. The importance of quality assurance programs for B-mode ultrasound image quality using ultrasound phantoms is well documented in the human medical and medical physics literature. The purpose of this prospective, cross-sectional, survey study was to determine the prevalence and methodology of quality acceptance testing and quality control testing of image quality for ultrasound system/components among veterinary sonographers. An online electronic survey was sent to 1497 members of veterinary imaging organizations: the American College of Veterinary Radiology, the Veterinary Ultrasound Society, and the European Association of Veterinary Diagnostic Imaging, and a total of 167 responses were received. The results showed that the percentages of veterinary sonographers performing quality acceptance testing and quality control testing are 42% (64/151; 95% confidence interval 34-52%) and 26% (40/156: 95% confidence interval 19-33%) respectively. Of the respondents who claimed to have quality acceptance testing or quality control testing of image quality in place for their ultrasound system/components, 0% have performed quality acceptance testing or quality control testing correctly (quality acceptance testing 95% confidence interval: 0-6%, quality control testing 95% confidence interval: 0-11%). Further education and guidelines are recommended for veterinary sonographers in the area of quality acceptance testing and quality control testing for B-mode ultrasound equipment/components. © 2018 American College of Veterinary Radiology.
46 CFR 164.019-13 - Production quality control requirements.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 46 Shipping 6 2011-10-01 2011-10-01 false Production quality control requirements. 164.019-13....019-13 Production quality control requirements. (a) General. Each component manufacturer shall establish procedures for maintaining quality control of the materials used in production, manufacturing...
46 CFR 164.019-13 - Production quality control requirements.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 46 Shipping 6 2012-10-01 2012-10-01 false Production quality control requirements. 164.019-13....019-13 Production quality control requirements. (a) General. Each component manufacturer shall establish procedures for maintaining quality control of the materials used in production, manufacturing...
46 CFR 164.019-13 - Production quality control requirements.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 6 2010-10-01 2010-10-01 false Production quality control requirements. 164.019-13....019-13 Production quality control requirements. (a) General. Each component manufacturer shall establish procedures for maintaining quality control of the materials used in production, manufacturing...
46 CFR 164.019-13 - Production quality control requirements.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 46 Shipping 6 2014-10-01 2014-10-01 false Production quality control requirements. 164.019-13....019-13 Production quality control requirements. (a) General. Each component manufacturer shall establish procedures for maintaining quality control of the materials used in production, manufacturing...
46 CFR 164.019-13 - Production quality control requirements.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 46 Shipping 6 2013-10-01 2013-10-01 false Production quality control requirements. 164.019-13....019-13 Production quality control requirements. (a) General. Each component manufacturer shall establish procedures for maintaining quality control of the materials used in production, manufacturing...
7 CFR 275.10 - Scope and purpose.
Code of Federal Regulations, 2010 CFR
2010-01-01
... to enhanced funding. (b) The objectives of quality control reviews are to provide: (1) A systematic... FOOD STAMP AND FOOD DISTRIBUTION PROGRAM PERFORMANCE REPORTING SYSTEM Quality Control (QC) Reviews... responsible for conducting quality control reviews. For food stamp quality control reviews, a sample of...
40 CFR 51.359 - Quality control.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 2 2014-07-01 2014-07-01 false Quality control. 51.359 Section 51.359 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS REQUIREMENTS FOR... to assure test accuracy. Computer control of quality assurance checks and quality control charts...
Quality Assurance of Chemical Measurements.
ERIC Educational Resources Information Center
Taylor, John K.
1981-01-01
Reviews aspects of quality control (methods to control errors) and quality assessment (verification that systems are operating within acceptable limits) including an analytical measurement system, quality control by inspection, control charts, systematic errors, and use of SRMs, materials for which properties are certified by the National Bureau…
14 CFR 21.143 - Quality control data requirements; prime manufacturer.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Quality control data requirements; prime... describing assigned responsibilities and delegated authority of the quality control organization, together with a chart indicating the functional relationship of the quality control organization to management...
40 CFR 81.51 - Portland Interstate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Control Region. 81.51 Section 81.51 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.51 Portland Interstate Air Quality Control Region. The Portland Interstate...
40 CFR 81.51 - Portland Interstate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... Control Region. 81.51 Section 81.51 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.51 Portland Interstate Air Quality Control Region. The Portland Interstate...
40 CFR 81.51 - Portland Interstate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... Control Region. 81.51 Section 81.51 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.51 Portland Interstate Air Quality Control Region. The Portland Interstate...
7 CFR 981.42 - Quality control.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 7 Agriculture 8 2012-01-01 2012-01-01 false Quality control. 981.42 Section 981.42 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Regulating Handling Quality Control § 981.42 Quality control. (a) Incoming. Except as provided in this...
7 CFR 981.42 - Quality control.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 7 Agriculture 8 2013-01-01 2013-01-01 false Quality control. 981.42 Section 981.42 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... Regulating Handling Quality Control § 981.42 Quality control. (a) Incoming. Except as provided in this...
7 CFR 981.42 - Quality control.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 7 Agriculture 8 2011-01-01 2011-01-01 false Quality control. 981.42 Section 981.42 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Regulating Handling Quality Control § 981.42 Quality control. (a) Incoming. Except as provided in this...
7 CFR 981.42 - Quality control.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 7 Agriculture 8 2010-01-01 2010-01-01 false Quality control. 981.42 Section 981.42 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Regulating Handling Quality Control § 981.42 Quality control. (a) Incoming. Except as provided in this...
40 CFR 60.2170 - Is there a minimum amount of monitoring data I must obtain?
Code of Federal Regulations, 2013 CFR
2013-07-01
... monitoring system quality assurance or quality control activities (including, as applicable, calibration... required monitoring system quality assurance or quality control activities including, as applicable... required monitoring system quality assurance or control activities in calculations used to report emissions...
40 CFR 81.74 - Northwest Pennsylvania-Youngstown Interstate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Northwest Pennsylvania-Youngstown... Designation of Air Quality Control Regions § 81.74 Northwest Pennsylvania-Youngstown Interstate Air Quality Control Region. The Northwest Pennsylvania-Youngstown Interstate Air Quality Control Region (Pennsylvania...
18 CFR 12.40 - Quality control programs.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Quality control... PROJECT WORKS Other Responsibilities of Applicant or Licensee § 12.40 Quality control programs. (a... meeting any requirements or standards set by the Regional Engineer. If a quality control program is...
22 CFR 96.39 - Information disclosure and quality control practices.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Information disclosure and quality control... for Convention Accreditation and Approval Information Disclosure, Fee Practices, and Quality Control Policies and Practices § 96.39 Information disclosure and quality control practices. (a) The agency or...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-11-18
... Information Collection: Quality Control for Rental Assistance Subsidy Determinations AGENCY: Office of the... Collection Title of Information Collection: Quality Control for Rental Assistance Subsidy Determinations. OMB... Quality Control process involves selecting a nationally representative sample of assisted households to...
18 CFR 12.40 - Quality control programs.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Quality control... PROJECT WORKS Other Responsibilities of Applicant or Licensee § 12.40 Quality control programs. (a... meeting any requirements or standards set by the Regional Engineer. If a quality control program is...
22 CFR 96.39 - Information disclosure and quality control practices.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Information disclosure and quality control... for Convention Accreditation and Approval Information Disclosure, Fee Practices, and Quality Control Policies and Practices § 96.39 Information disclosure and quality control practices. (a) The agency or...
22 CFR 96.39 - Information disclosure and quality control practices.
Code of Federal Regulations, 2014 CFR
2014-04-01
... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Information disclosure and quality control... for Convention Accreditation and Approval Information Disclosure, Fee Practices, and Quality Control Policies and Practices § 96.39 Information disclosure and quality control practices. (a) The agency or...
22 CFR 96.39 - Information disclosure and quality control practices.
Code of Federal Regulations, 2012 CFR
2012-04-01
... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Information disclosure and quality control... for Convention Accreditation and Approval Information Disclosure, Fee Practices, and Quality Control Policies and Practices § 96.39 Information disclosure and quality control practices. (a) The agency or...
22 CFR 96.39 - Information disclosure and quality control practices.
Code of Federal Regulations, 2013 CFR
2013-04-01
... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Information disclosure and quality control... for Convention Accreditation and Approval Information Disclosure, Fee Practices, and Quality Control Policies and Practices § 96.39 Information disclosure and quality control practices. (a) The agency or...
40 CFR 81.167 - Southeast Desert Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Southeast Desert Intrastate Air... Air Quality Control Regions § 81.167 Southeast Desert Intrastate Air Quality Control Region. The Southeast Desert Intrastate Air Quality Control Region (California) consists of the territorial area...
40 CFR 81.167 - Southeast Desert Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Southeast Desert Intrastate Air... Air Quality Control Regions § 81.167 Southeast Desert Intrastate Air Quality Control Region. The Southeast Desert Intrastate Air Quality Control Region (California) consists of the territorial area...
40 CFR 81.167 - Southeast Desert Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Southeast Desert Intrastate Air... Air Quality Control Regions § 81.167 Southeast Desert Intrastate Air Quality Control Region. The Southeast Desert Intrastate Air Quality Control Region (California) consists of the territorial area...
7 CFR 930.44 - Quality control.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 7 Agriculture 8 2011-01-01 2011-01-01 false Quality control. 930.44 Section 930.44 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Control § 930.44 Quality control. (a) Quality standards. The Board may establish, with the approval of the...
7 CFR 930.44 - Quality control.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 7 Agriculture 8 2010-01-01 2010-01-01 false Quality control. 930.44 Section 930.44 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Control § 930.44 Quality control. (a) Quality standards. The Board may establish, with the approval of the...
7 CFR 930.44 - Quality control.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 7 Agriculture 8 2012-01-01 2012-01-01 false Quality control. 930.44 Section 930.44 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Control § 930.44 Quality control. (a) Quality standards. The Board may establish, with the approval of the...
7 CFR 930.44 - Quality control.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 7 Agriculture 8 2013-01-01 2013-01-01 false Quality control. 930.44 Section 930.44 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... Control § 930.44 Quality control. (a) Quality standards. The Board may establish, with the approval of the...
40 CFR 81.216 - Northeast Indiana Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Northeast Indiana Intrastate Air... Air Quality Control Regions § 81.216 Northeast Indiana Intrastate Air Quality Control Region. The Northeast Indiana Intrastate Air Quality Control Region (Indiana) consists of the territorial area...
40 CFR 81.162 - Northeast Plateau Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Northeast Plateau Intrastate Air... Air Quality Control Regions § 81.162 Northeast Plateau Intrastate Air Quality Control Region. The Northeast Plateau Intrastate Air Quality Control Region (California) consists of the territorial area...
Quality assurance: Importance of systems and standard operating procedures
Manghani, Kishu
2011-01-01
It is mandatory for sponsors of clinical trials and contract research organizations alike to establish, manage and monitor their quality control and quality assurance systems and their integral standard operating procedures and other quality documents to provide high-quality products and services to fully satisfy customer needs and expectations. Quality control and quality assurance systems together constitute the key quality systems. Quality control and quality assurance are parts of quality management. Quality control is focused on fulfilling quality requirements, whereas quality assurance is focused on providing confidence that quality requirements are fulfilled. The quality systems must be commensurate with the Company business objectives and business model. Top management commitment and its active involvement are critical in order to ensure at all times the adequacy, suitability, effectiveness and efficiency of the quality systems. Effective and efficient quality systems can promote timely registration of drugs by eliminating waste and the need for rework with overall financial and social benefits to the Company. PMID:21584180
Quality assurance: Importance of systems and standard operating procedures.
Manghani, Kishu
2011-01-01
It is mandatory for sponsors of clinical trials and contract research organizations alike to establish, manage and monitor their quality control and quality assurance systems and their integral standard operating procedures and other quality documents to provide high-quality products and services to fully satisfy customer needs and expectations. Quality control and quality assurance systems together constitute the key quality systems. Quality control and quality assurance are parts of quality management. Quality control is focused on fulfilling quality requirements, whereas quality assurance is focused on providing confidence that quality requirements are fulfilled. The quality systems must be commensurate with the Company business objectives and business model. Top management commitment and its active involvement are critical in order to ensure at all times the adequacy, suitability, effectiveness and efficiency of the quality systems. Effective and efficient quality systems can promote timely registration of drugs by eliminating waste and the need for rework with overall financial and social benefits to the Company.
40 CFR 81.36 - Maricopa Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Maricopa Intrastate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.36 Maricopa Intrastate Air Quality Control Region. The Phoenix-Tucson...
40 CFR 81.42 - Chattanooga Interstate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Chattanooga Interstate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.42 Chattanooga Interstate Air Quality Control Region. The Chattanooga...
40 CFR 81.51 - Portland Interstate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Portland Interstate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.51 Portland Interstate Air Quality Control Region. The Portland Interstate...
40 CFR 81.35 - Louisville Interstate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Louisville Interstate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.35 Louisville Interstate Air Quality Control Region. The Louisville...
40 CFR 81.36 - Maricopa Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Maricopa Intrastate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.36 Maricopa Intrastate Air Quality Control Region. The Phoenix-Tucson...
40 CFR 81.42 - Chattanooga Interstate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Chattanooga Interstate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.42 Chattanooga Interstate Air Quality Control Region. The Chattanooga...
40 CFR 81.36 - Maricopa Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Maricopa Intrastate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.36 Maricopa Intrastate Air Quality Control Region. The Phoenix-Tucson...
40 CFR 81.42 - Chattanooga Interstate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Chattanooga Interstate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.42 Chattanooga Interstate Air Quality Control Region. The Chattanooga...
40 CFR 81.35 - Louisville Interstate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Louisville Interstate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.35 Louisville Interstate Air Quality Control Region. The Louisville...
40 CFR 81.36 - Maricopa Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Maricopa Intrastate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.36 Maricopa Intrastate Air Quality Control Region. The Phoenix-Tucson...
40 CFR 81.42 - Chattanooga Interstate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Chattanooga Interstate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.42 Chattanooga Interstate Air Quality Control Region. The Chattanooga...
40 CFR 81.35 - Louisville Interstate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Louisville Interstate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.35 Louisville Interstate Air Quality Control Region. The Louisville...
40 CFR 81.35 - Louisville Interstate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Louisville Interstate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.35 Louisville Interstate Air Quality Control Region. The Louisville...
40 CFR 81.42 - Chattanooga Interstate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Chattanooga Interstate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.42 Chattanooga Interstate Air Quality Control Region. The Chattanooga...
40 CFR 81.35 - Louisville Interstate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Louisville Interstate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.35 Louisville Interstate Air Quality Control Region. The Louisville...
40 CFR 81.36 - Maricopa Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Maricopa Intrastate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.36 Maricopa Intrastate Air Quality Control Region. The Phoenix-Tucson...
40 CFR 81.51 - Portland Interstate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Portland Interstate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.51 Portland Interstate Air Quality Control Region. The Portland Interstate...
Zhong, C Q; He, N; Hua, M Q; Wei, X D; Ma, D X; Ji, C Y
2016-09-14
Objective: To set internal quality control system of BCR-ABL (P210) transcript levels for real-time quantitative PCR (RQ-PCR). Methods: Using K562 cells and HL-60 cells, we prepared high- and low-level BCR-ABL internal quality control substance. The BCR-ABL (P210) transcript levels of internal quality control substance have been determined for 184 times together with clinical samples from August 2013 to October 2015. The slope rate, intercept and correlation coefficient of standard curve were calculated according to different reagent lots (lots number 20130303, 20131212, 20140411 and 20150327 are called R1、R2、R3 and R4 for short respectively), and the detection results of quality control substance were calculated according to different reagent lots and quality control substance lots (lots number 20130725, 20140611 are called Q1、Q2 for short respectively). Then the results were analyzed by Levey-Jennings quality control chart combined with Westgard multi-rules theory. Results: ①We analyzed the slope rate and intercept of standard curve. Fifty-three times of the R1 reagent detection, 80 times of the R3 reagent detection and 14 times of the R4 reagent detection were all under control. For 37 times detection of R2 reagent, the slope rate was out of control for 6 times. It was lower than x - s for the 2-8 tests and upper the average for the 12-37 tests. The intercept was out of control for 9 times, upper the x + s for the 1-8 tests and lower the average for the 12-37 tests. ② According to the detection results of quality control substance, for Q1 quality control substance, 49 tests by R1 reagent were under control, and 1 out of 23 tests by R2 reagent was out of control. For Q2 quality control substance, 14 tests by R2 reagent detection, 72 tests by R3 reagent detection and 14 tests by R4 reagent were all under control. Conclusion: The preparation of high- and low-level quality control substance using K562 and HL-60 cells was convenient and the detection results were reliable and stable. The application of quality control substance combined with slope rate and intercept in the internal quality control may contribute to quality assurance for quantitative detection of BCR-ABL (P210) transcript levels.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 46 Shipping 6 2014-10-01 2014-10-01 false Production inspections, tests, quality control, and..., quality control, and conformance of release mechanisms. (a) Unless the Commandant directs otherwise, an... prescribe additional production tests and inspections necessary to maintain quality control and to monitor...
Code of Federal Regulations, 2012 CFR
2012-10-01
... 46 Shipping 6 2012-10-01 2012-10-01 false Production inspections, tests, quality control, and..., quality control, and conformance of release mechanisms. (a) Unless the Commandant directs otherwise, an... prescribe additional production tests and inspections necessary to maintain quality control and to monitor...
Code of Federal Regulations, 2014 CFR
2014-10-01
... 46 Shipping 6 2014-10-01 2014-10-01 false Production inspections, tests, quality control, and..., quality control, and conformance of release mechanisms. (a) Unless the Commandant directs otherwise, an... prescribe additional production tests and inspections necessary to maintain quality control and to monitor...
Code of Federal Regulations, 2013 CFR
2013-10-01
... 46 Shipping 6 2013-10-01 2013-10-01 false Production inspections, tests, quality control, and..., quality control, and conformance of release mechanisms. (a) Unless the Commandant directs otherwise, an... prescribe additional production tests and inspections necessary to maintain quality control and to monitor...
40 CFR 81.221 - Southwest Oregon Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Southwest Oregon Intrastate Air... Air Quality Control Regions § 81.221 Southwest Oregon Intrastate Air Quality Control Region. The Southwest Oregon Intrastate Air Quality Control Region consists of the territorial area encompassed by the...
40 CFR 81.249 - Northwest Oregon Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Northwest Oregon Intrastate Air... Air Quality Control Regions § 81.249 Northwest Oregon Intrastate Air Quality Control Region. The Northwest Oregon Intrastate Air Quality Control Region consists of the territorial area encompassed by the...
40 CFR 81.249 - Northwest Oregon Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Northwest Oregon Intrastate Air... Air Quality Control Regions § 81.249 Northwest Oregon Intrastate Air Quality Control Region. The Northwest Oregon Intrastate Air Quality Control Region consists of the territorial area encompassed by the...
40 CFR 81.249 - Northwest Oregon Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Northwest Oregon Intrastate Air... Air Quality Control Regions § 81.249 Northwest Oregon Intrastate Air Quality Control Region. The Northwest Oregon Intrastate Air Quality Control Region consists of the territorial area encompassed by the...
40 CFR 81.221 - Southwest Oregon Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Southwest Oregon Intrastate Air... Air Quality Control Regions § 81.221 Southwest Oregon Intrastate Air Quality Control Region. The Southwest Oregon Intrastate Air Quality Control Region consists of the territorial area encompassed by the...
40 CFR 81.221 - Southwest Oregon Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Southwest Oregon Intrastate Air... Air Quality Control Regions § 81.221 Southwest Oregon Intrastate Air Quality Control Region. The Southwest Oregon Intrastate Air Quality Control Region consists of the territorial area encompassed by the...
40 CFR 81.249 - Northwest Oregon Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Northwest Oregon Intrastate Air... Air Quality Control Regions § 81.249 Northwest Oregon Intrastate Air Quality Control Region. The Northwest Oregon Intrastate Air Quality Control Region consists of the territorial area encompassed by the...
40 CFR 81.249 - Northwest Oregon Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Northwest Oregon Intrastate Air... Air Quality Control Regions § 81.249 Northwest Oregon Intrastate Air Quality Control Region. The Northwest Oregon Intrastate Air Quality Control Region consists of the territorial area encompassed by the...
40 CFR 81.221 - Southwest Oregon Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Southwest Oregon Intrastate Air... Air Quality Control Regions § 81.221 Southwest Oregon Intrastate Air Quality Control Region. The Southwest Oregon Intrastate Air Quality Control Region consists of the territorial area encompassed by the...
40 CFR 81.221 - Southwest Oregon Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Southwest Oregon Intrastate Air... Air Quality Control Regions § 81.221 Southwest Oregon Intrastate Air Quality Control Region. The Southwest Oregon Intrastate Air Quality Control Region consists of the territorial area encompassed by the...
40 CFR 81.60 - Duluth (Minnesota)-Superior (Wisconsin) Interstate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Duluth (Minnesota)-Superior (Wisconsin... Designation of Air Quality Control Regions § 81.60 Duluth (Minnesota)-Superior (Wisconsin) Interstate Air Quality Control Region. The Duluth (Minnesota)-Superior (Wisconsin) Interstate Air Quality Control Region...
40 CFR 81.245 - Southwest Minnesota Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Southwest Minnesota Intrastate Air... Air Quality Control Regions § 81.245 Southwest Minnesota Intrastate Air Quality Control Region. The Southwest Minnesota Intrastate Air Quality Control Region consists of the territorial area encompassed by...
40 CFR 81.243 - Central Minnesota Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Central Minnesota Intrastate Air... Air Quality Control Regions § 81.243 Central Minnesota Intrastate Air Quality Control Region. The Central Minnesota Intrastate Air Quality Control Region consists of the territorial area encompassed by...
40 CFR 81.243 - Central Minnesota Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Central Minnesota Intrastate Air... Air Quality Control Regions § 81.243 Central Minnesota Intrastate Air Quality Control Region. The Central Minnesota Intrastate Air Quality Control Region consists of the territorial area encompassed by...
40 CFR 81.245 - Southwest Minnesota Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Southwest Minnesota Intrastate Air... Air Quality Control Regions § 81.245 Southwest Minnesota Intrastate Air Quality Control Region. The Southwest Minnesota Intrastate Air Quality Control Region consists of the territorial area encompassed by...
40 CFR 81.60 - Duluth (Minnesota)-Superior (Wisconsin) Interstate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Duluth (Minnesota)-Superior (Wisconsin... Designation of Air Quality Control Regions § 81.60 Duluth (Minnesota)-Superior (Wisconsin) Interstate Air Quality Control Region. The Duluth (Minnesota)-Superior (Wisconsin) Interstate Air Quality Control Region...
40 CFR 81.243 - Central Minnesota Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Central Minnesota Intrastate Air... Air Quality Control Regions § 81.243 Central Minnesota Intrastate Air Quality Control Region. The Central Minnesota Intrastate Air Quality Control Region consists of the territorial area encompassed by...
40 CFR 81.244 - Northwest Minnesota Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Northwest Minnesota Intrastate Air... Air Quality Control Regions § 81.244 Northwest Minnesota Intrastate Air Quality Control Region. The Northwest Minnesota Intrastate Air Quality Control Region consists of the territorial area encompassed by...
40 CFR 81.245 - Southwest Minnesota Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Southwest Minnesota Intrastate Air... Air Quality Control Regions § 81.245 Southwest Minnesota Intrastate Air Quality Control Region. The Southwest Minnesota Intrastate Air Quality Control Region consists of the territorial area encompassed by...
40 CFR 81.245 - Southwest Minnesota Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Southwest Minnesota Intrastate Air... Air Quality Control Regions § 81.245 Southwest Minnesota Intrastate Air Quality Control Region. The Southwest Minnesota Intrastate Air Quality Control Region consists of the territorial area encompassed by...
40 CFR 81.245 - Southwest Minnesota Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Southwest Minnesota Intrastate Air... Air Quality Control Regions § 81.245 Southwest Minnesota Intrastate Air Quality Control Region. The Southwest Minnesota Intrastate Air Quality Control Region consists of the territorial area encompassed by...
40 CFR 81.60 - Duluth (Minnesota)-Superior (Wisconsin) Interstate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Duluth (Minnesota)-Superior (Wisconsin... Designation of Air Quality Control Regions § 81.60 Duluth (Minnesota)-Superior (Wisconsin) Interstate Air Quality Control Region. The Duluth (Minnesota)-Superior (Wisconsin) Interstate Air Quality Control Region...
40 CFR 81.243 - Central Minnesota Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Central Minnesota Intrastate Air... Air Quality Control Regions § 81.243 Central Minnesota Intrastate Air Quality Control Region. The Central Minnesota Intrastate Air Quality Control Region consists of the territorial area encompassed by...
40 CFR 81.244 - Northwest Minnesota Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Northwest Minnesota Intrastate Air... Air Quality Control Regions § 81.244 Northwest Minnesota Intrastate Air Quality Control Region. The Northwest Minnesota Intrastate Air Quality Control Region consists of the territorial area encompassed by...
40 CFR 81.244 - Northwest Minnesota Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Northwest Minnesota Intrastate Air... Air Quality Control Regions § 81.244 Northwest Minnesota Intrastate Air Quality Control Region. The Northwest Minnesota Intrastate Air Quality Control Region consists of the territorial area encompassed by...
40 CFR 81.60 - Duluth (Minnesota)-Superior (Wisconsin) Interstate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Duluth (Minnesota)-Superior (Wisconsin... Designation of Air Quality Control Regions § 81.60 Duluth (Minnesota)-Superior (Wisconsin) Interstate Air Quality Control Region. The Duluth (Minnesota)-Superior (Wisconsin) Interstate Air Quality Control Region...
40 CFR 81.244 - Northwest Minnesota Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Northwest Minnesota Intrastate Air... Air Quality Control Regions § 81.244 Northwest Minnesota Intrastate Air Quality Control Region. The Northwest Minnesota Intrastate Air Quality Control Region consists of the territorial area encompassed by...
40 CFR 81.243 - Central Minnesota Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Central Minnesota Intrastate Air... Air Quality Control Regions § 81.243 Central Minnesota Intrastate Air Quality Control Region. The Central Minnesota Intrastate Air Quality Control Region consists of the territorial area encompassed by...
40 CFR 81.60 - Duluth (Minnesota)-Superior (Wisconsin) Interstate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Duluth (Minnesota)-Superior (Wisconsin... Designation of Air Quality Control Regions § 81.60 Duluth (Minnesota)-Superior (Wisconsin) Interstate Air Quality Control Region. The Duluth (Minnesota)-Superior (Wisconsin) Interstate Air Quality Control Region...
40 CFR 81.170 - Miles City Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Miles City Intrastate Air Quality Control Region. 81.170 Section 81.170 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... Quality Control Regions § 81.170 Miles City Intrastate Air Quality Control Region. The Miles City...
40 CFR 81.170 - Miles City Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Miles City Intrastate Air Quality Control Region. 81.170 Section 81.170 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... Quality Control Regions § 81.170 Miles City Intrastate Air Quality Control Region. The Miles City...
40 CFR 81.170 - Miles City Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Miles City Intrastate Air Quality Control Region. 81.170 Section 81.170 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... Quality Control Regions § 81.170 Miles City Intrastate Air Quality Control Region. The Miles City...
Code of Federal Regulations, 2010 CFR
2010-07-01
... Air Quality Control Region (Pennsylvania-New Jersey-Delaware). 81.15 Section 81.15 Protection of... Interstate Air Quality Control Region (Pennsylvania-New Jersey-Delaware). The Metropolitan Philadelphia Interstate Air Quality Control Region (Pennsylvania-New Jersey-Delaware) consists of the territorial area...
40 CFR 81.105 - South Central Pennsylvania Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false South Central Pennsylvania Intrastate... Designation of Air Quality Control Regions § 81.105 South Central Pennsylvania Intrastate Air Quality Control Region. The South Central Pennsylvania Intrastate Air Quality Control Region consists of the territorial...
40 CFR 81.152 - Southern Coastal Plain Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Southern Coastal Plain Intrastate Air Quality Control Region. 81.152 Section 81.152 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.152 Southern Coastal Plain Intrastate Air Quality Control Region. The...
40 CFR 81.149 - Northern Coastal Plain Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Northern Coastal Plain Intrastate Air Quality Control Region. 81.149 Section 81.149 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.149 Northern Coastal Plain Intrastate Air Quality Control Region. The...
40 CFR 81.149 - Northern Coastal Plain Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Northern Coastal Plain Intrastate Air Quality Control Region. 81.149 Section 81.149 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.149 Northern Coastal Plain Intrastate Air Quality Control Region. The...
40 CFR 81.152 - Southern Coastal Plain Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Southern Coastal Plain Intrastate Air Quality Control Region. 81.152 Section 81.152 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.152 Southern Coastal Plain Intrastate Air Quality Control Region. The...
40 CFR 81.152 - Southern Coastal Plain Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Southern Coastal Plain Intrastate Air Quality Control Region. 81.152 Section 81.152 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.152 Southern Coastal Plain Intrastate Air Quality Control Region. The...
40 CFR 81.152 - Southern Coastal Plain Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Southern Coastal Plain Intrastate Air Quality Control Region. 81.152 Section 81.152 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.152 Southern Coastal Plain Intrastate Air Quality Control Region. The...
40 CFR 81.149 - Northern Coastal Plain Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Northern Coastal Plain Intrastate Air Quality Control Region. 81.149 Section 81.149 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.149 Northern Coastal Plain Intrastate Air Quality Control Region. The...
40 CFR 81.152 - Southern Coastal Plain Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Southern Coastal Plain Intrastate Air Quality Control Region. 81.152 Section 81.152 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.152 Southern Coastal Plain Intrastate Air Quality Control Region. The...
40 CFR 81.149 - Northern Coastal Plain Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Northern Coastal Plain Intrastate Air Quality Control Region. 81.149 Section 81.149 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.149 Northern Coastal Plain Intrastate Air Quality Control Region. The...
40 CFR 81.149 - Northern Coastal Plain Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Northern Coastal Plain Intrastate Air Quality Control Region. 81.149 Section 81.149 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.149 Northern Coastal Plain Intrastate Air Quality Control Region. The...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-04-27
... Proposed Information Collection to OMB; Quality Control Requirements for Direct Endorsement Lenders AGENCY... lists the following information: Title of Proposal: Quality Control Requirements for Direct Endorsement... meet FHA's quality control requirements in light of recent changes to lender eligibility criteria for...
14 CFR 145.211 - Quality control system.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Quality control system. 145.211 Section 145...) SCHOOLS AND OTHER CERTIFICATED AGENCIES REPAIR STATIONS Operating Rules § 145.211 Quality control system. (a) A certificated repair station must establish and maintain a quality control system acceptable to...
14 CFR 21.147 - Changes in quality control system.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Changes in quality control system. 21.147 Section 21.147 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION... quality control system. After the issue of a production certificate, each change to the quality control...
14 CFR 21.147 - Changes in quality control system.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Changes in quality control system. 21.147 Section 21.147 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION... quality control system. After the issue of a production certificate, each change to the quality control...
7 CFR 275.21 - Quality control review reports.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 7 Agriculture 4 2011-01-01 2011-01-01 false Quality control review reports. 275.21 Section 275.21... Reporting on Program Performance § 275.21 Quality control review reports. (a) General. Each State agency shall submit reports on the performance of quality control reviews in accordance with the requirements...
40 CFR 81.274 - Mountain Counties Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Mountain Counties Intrastate Air... Air Quality Control Regions § 81.274 Mountain Counties Intrastate Air Quality Control Region. The Mountain Counties Intrastate Air Quality Control Region consists of the territorial area encompassed by the...
40 CFR 81.274 - Mountain Counties Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Mountain Counties Intrastate Air... Air Quality Control Regions § 81.274 Mountain Counties Intrastate Air Quality Control Region. The Mountain Counties Intrastate Air Quality Control Region consists of the territorial area encompassed by the...
40 CFR 81.274 - Mountain Counties Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Mountain Counties Intrastate Air... Air Quality Control Regions § 81.274 Mountain Counties Intrastate Air Quality Control Region. The Mountain Counties Intrastate Air Quality Control Region consists of the territorial area encompassed by the...
40 CFR 81.87 - Metropolitan Boise Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Metropolitan Boise Intrastate Air Quality Control Region. 81.87 Section 81.87 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.87 Metropolitan Boise Intrastate Air Quality Control Region. The...
40 CFR 81.87 - Metropolitan Boise Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Metropolitan Boise Intrastate Air Quality Control Region. 81.87 Section 81.87 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.87 Metropolitan Boise Intrastate Air Quality Control Region. The...
14 CFR 145.211 - Quality control system.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Quality control system. 145.211 Section 145...) SCHOOLS AND OTHER CERTIFICATED AGENCIES REPAIR STATIONS Operating Rules § 145.211 Quality control system. (a) A certificated repair station must establish and maintain a quality control system acceptable to...
14 CFR 21.139 - Quality control.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Quality control. 21.139 Section 21.139... PROCEDURES FOR PRODUCTS AND PARTS Production Certificates § 21.139 Quality control. The applicant must show that he has established and can maintain a quality control system for any product, for which he...
21 CFR 864.8625 - Hematology quality control mixture.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Hematology quality control mixture. 864.8625 Section 864.8625 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... quality control mixture. (a) Identification. A hematology quality control mixture is a device used to...
40 CFR 81.100 - Eastern Washington-Northern Idaho Interstate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Eastern Washington-Northern Idaho... Designation of Air Quality Control Regions § 81.100 Eastern Washington-Northern Idaho Interstate Air Quality Control Region. The Eastern Washington-Northern Idaho Interstate Air Quality Control Region consists of...
40 CFR 81.82 - El Paso-Las Cruces-Alamogordo Interstate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Control Region. The El Paso-Las Cruces-Alamogordo Interstate Air Quality Control Region (New Mexico-Texas... Interstate Air Quality Control Region. 81.82 Section 81.82 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES...
40 CFR 81.82 - El Paso-Las Cruces-Alamogordo Interstate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Control Region. The El Paso-Las Cruces-Alamogordo Interstate Air Quality Control Region (New Mexico-Texas... Interstate Air Quality Control Region. 81.82 Section 81.82 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES...
40 CFR 81.27 - Minneapolis-St. Paul Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Minneapolis-St. Paul Intrastate Air... Air Quality Control Regions § 81.27 Minneapolis-St. Paul Intrastate Air Quality Control Region. The Minneapolis-St. Paul Intrastate Air Quality Control Region (Minnesota) consists of the territorial area...
40 CFR 81.81 - Merrimack Valley-Southern New Hampshire Interstate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... Designation of Air Quality Control Regions § 81.81 Merrimack Valley-Southern New Hampshire Interstate Air Quality Control Region. The Merrimack Valley Southern New Hampshire Interstate Air Quality Control Region (Massachusetts-New Hampshire) consists of the territorial area encompassed by the boundaries of the following...
40 CFR 81.81 - Merrimack Valley-Southern New Hampshire Interstate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Designation of Air Quality Control Regions § 81.81 Merrimack Valley-Southern New Hampshire Interstate Air Quality Control Region. The Merrimack Valley Southern New Hampshire Interstate Air Quality Control Region (Massachusetts-New Hampshire) consists of the territorial area encompassed by the boundaries of the following...
40 CFR 81.81 - Merrimack Valley-Southern New Hampshire Interstate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Designation of Air Quality Control Regions § 81.81 Merrimack Valley-Southern New Hampshire Interstate Air Quality Control Region. The Merrimack Valley Southern New Hampshire Interstate Air Quality Control Region (Massachusetts-New Hampshire) consists of the territorial area encompassed by the boundaries of the following...
40 CFR 81.81 - Merrimack Valley-Southern New Hampshire Interstate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... Designation of Air Quality Control Regions § 81.81 Merrimack Valley-Southern New Hampshire Interstate Air Quality Control Region. The Merrimack Valley Southern New Hampshire Interstate Air Quality Control Region (Massachusetts-New Hampshire) consists of the territorial area encompassed by the boundaries of the following...
40 CFR 81.81 - Merrimack Valley-Southern New Hampshire Interstate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... Designation of Air Quality Control Regions § 81.81 Merrimack Valley-Southern New Hampshire Interstate Air Quality Control Region. The Merrimack Valley Southern New Hampshire Interstate Air Quality Control Region (Massachusetts-New Hampshire) consists of the territorial area encompassed by the boundaries of the following...
40 CFR 81.133 - Amarillo-Lubbock Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Amarillo-Lubbock Intrastate Air Quality Control Region. 81.133 Section 81.133 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Air Quality Control Regions § 81.133 Amarillo-Lubbock Intrastate Air Quality Control Region. The...
40 CFR 81.168 - Great Falls Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Great Falls Intrastate Air Quality Control Region. 81.168 Section 81.168 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... Quality Control Regions § 81.168 Great Falls Intrastate Air Quality Control Region. The Great Falls...
40 CFR 81.168 - Great Falls Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Great Falls Intrastate Air Quality Control Region. 81.168 Section 81.168 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... Quality Control Regions § 81.168 Great Falls Intrastate Air Quality Control Region. The Great Falls...
40 CFR 81.85 - Metropolitan Sioux Falls Interstate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Metropolitan Sioux Falls Interstate... Designation of Air Quality Control Regions § 81.85 Metropolitan Sioux Falls Interstate Air Quality Control Region. The Metropolitan Sioux Falls Interstate Air Quality Control Region (Iowa-South Dakota) has been...
40 CFR 81.85 - Metropolitan Sioux Falls Interstate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Metropolitan Sioux Falls Interstate... Designation of Air Quality Control Regions § 81.85 Metropolitan Sioux Falls Interstate Air Quality Control Region. The Metropolitan Sioux Falls Interstate Air Quality Control Region (Iowa-South Dakota) has been...
40 CFR 81.85 - Metropolitan Sioux Falls Interstate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Metropolitan Sioux Falls Interstate... Designation of Air Quality Control Regions § 81.85 Metropolitan Sioux Falls Interstate Air Quality Control Region. The Metropolitan Sioux Falls Interstate Air Quality Control Region (Iowa-South Dakota) has been...
40 CFR 81.85 - Metropolitan Sioux Falls Interstate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Metropolitan Sioux Falls Interstate... Designation of Air Quality Control Regions § 81.85 Metropolitan Sioux Falls Interstate Air Quality Control Region. The Metropolitan Sioux Falls Interstate Air Quality Control Region (Iowa-South Dakota) has been...
40 CFR 81.132 - Abilene-Wichita Falls Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Abilene-Wichita Falls Intrastate Air... Air Quality Control Regions § 81.132 Abilene-Wichita Falls Intrastate Air Quality Control Region. The Abilene-Wichita Falls Intrastate Air Quality Control Region (Texas) consists of the territorial area...
40 CFR 81.168 - Great Falls Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Great Falls Intrastate Air Quality Control Region. 81.168 Section 81.168 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... Quality Control Regions § 81.168 Great Falls Intrastate Air Quality Control Region. The Great Falls...
40 CFR 81.132 - Abilene-Wichita Falls Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Abilene-Wichita Falls Intrastate Air... Air Quality Control Regions § 81.132 Abilene-Wichita Falls Intrastate Air Quality Control Region. The Abilene-Wichita Falls Intrastate Air Quality Control Region (Texas) consists of the territorial area...
40 CFR 81.132 - Abilene-Wichita Falls Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Abilene-Wichita Falls Intrastate Air... Air Quality Control Regions § 81.132 Abilene-Wichita Falls Intrastate Air Quality Control Region. The Abilene-Wichita Falls Intrastate Air Quality Control Region (Texas) consists of the territorial area...
40 CFR 81.168 - Great Falls Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Great Falls Intrastate Air Quality Control Region. 81.168 Section 81.168 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... Quality Control Regions § 81.168 Great Falls Intrastate Air Quality Control Region. The Great Falls...
40 CFR 81.168 - Great Falls Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Great Falls Intrastate Air Quality Control Region. 81.168 Section 81.168 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... Quality Control Regions § 81.168 Great Falls Intrastate Air Quality Control Region. The Great Falls...
40 CFR 81.132 - Abilene-Wichita Falls Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Abilene-Wichita Falls Intrastate Air... Air Quality Control Regions § 81.132 Abilene-Wichita Falls Intrastate Air Quality Control Region. The Abilene-Wichita Falls Intrastate Air Quality Control Region (Texas) consists of the territorial area...
40 CFR 81.85 - Metropolitan Sioux Falls Interstate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Metropolitan Sioux Falls Interstate... Designation of Air Quality Control Regions § 81.85 Metropolitan Sioux Falls Interstate Air Quality Control Region. The Metropolitan Sioux Falls Interstate Air Quality Control Region (Iowa-South Dakota) has been...
40 CFR 81.132 - Abilene-Wichita Falls Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Abilene-Wichita Falls Intrastate Air... Air Quality Control Regions § 81.132 Abilene-Wichita Falls Intrastate Air Quality Control Region. The Abilene-Wichita Falls Intrastate Air Quality Control Region (Texas) consists of the territorial area...
40 CFR 62.7856 - Albuquerque/Bernalillo County Air Quality Control Board.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Albuquerque/Bernalillo County Air Quality Control Board. (a) Identification of Plan. Albuquerque-Bernalillo... County Air Quality Control Board on November 9, 2005. (b) Identification of Sources. The plan applies to... County Air Quality Control Board that commenced construction prior to May 30, 1991, and have not been...
33 CFR 385.21 - Quality control.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 33 Navigation and Navigable Waters 3 2011-07-01 2011-07-01 false Quality control. 385.21 Section... Processes § 385.21 Quality control. (a) The Corps of Engineers and the non-Federal sponsor shall prepare a quality control plan, in accordance with applicable Corps of Engineers regulations, for each product that...
14 CFR 21.139 - Quality control.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Quality control. 21.139 Section 21.139... PROCEDURES FOR PRODUCTS AND PARTS Production Certificates § 21.139 Quality control. The applicant must show that he has established and can maintain a quality control system for any product, for which he...
33 CFR 385.21 - Quality control.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 33 Navigation and Navigable Waters 3 2013-07-01 2013-07-01 false Quality control. 385.21 Section... Processes § 385.21 Quality control. (a) The Corps of Engineers and the non-Federal sponsor shall prepare a quality control plan, in accordance with applicable Corps of Engineers regulations, for each product that...
33 CFR 385.21 - Quality control.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Quality control. 385.21 Section... Processes § 385.21 Quality control. (a) The Corps of Engineers and the non-Federal sponsor shall prepare a quality control plan, in accordance with applicable Corps of Engineers regulations, for each product that...
40 CFR 81.176 - San Luis Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false San Luis Intrastate Air Quality Control Region. 81.176 Section 81.176 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... Quality Control Regions § 81.176 San Luis Intrastate Air Quality Control Region. The San Luis Intrastate...
40 CFR 81.94 - Shreveport-Texarkana-Tyler Interstate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Shreveport-Texarkana-Tyler Interstate... Designation of Air Quality Control Regions § 81.94 Shreveport-Texarkana-Tyler Interstate Air Quality Control Region. The Shreveport-Texarkana-Tyler Interstate Air Quality Control Region (Arkansas-Louisiana-Oklahoma...
40 CFR 81.94 - Shreveport-Texarkana-Tyler Interstate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Shreveport-Texarkana-Tyler Interstate... Designation of Air Quality Control Regions § 81.94 Shreveport-Texarkana-Tyler Interstate Air Quality Control Region. The Shreveport-Texarkana-Tyler Interstate Air Quality Control Region (Arkansas-Louisiana-Oklahoma...
40 CFR 81.94 - Shreveport-Texarkana-Tyler Interstate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Shreveport-Texarkana-Tyler Interstate... Designation of Air Quality Control Regions § 81.94 Shreveport-Texarkana-Tyler Interstate Air Quality Control Region. The Shreveport-Texarkana-Tyler Interstate Air Quality Control Region (Arkansas-Louisiana-Oklahoma...
40 CFR 81.94 - Shreveport-Texarkana-Tyler Interstate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Shreveport-Texarkana-Tyler Interstate... Designation of Air Quality Control Regions § 81.94 Shreveport-Texarkana-Tyler Interstate Air Quality Control Region. The Shreveport-Texarkana-Tyler Interstate Air Quality Control Region (Arkansas-Louisiana-Oklahoma...
40 CFR 81.94 - Shreveport-Texarkana-Tyler Interstate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Shreveport-Texarkana-Tyler Interstate... Designation of Air Quality Control Regions § 81.94 Shreveport-Texarkana-Tyler Interstate Air Quality Control Region. The Shreveport-Texarkana-Tyler Interstate Air Quality Control Region (Arkansas-Louisiana-Oklahoma...
40 CFR 81.65 - Joplin (Missouri)-Northeast Oklahoma Interstate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Joplin (Missouri)-Northeast Oklahoma... Designation of Air Quality Control Regions § 81.65 Joplin (Missouri)-Northeast Oklahoma Interstate Air Quality Control Region. The Joplin (Missouri)-Northeast Oklahoma Interstate Air Quality Control Region, designated...
40 CFR 81.237 - Northeast Georgia Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Northeast Georgia Intrastate Air... Air Quality Control Regions § 81.237 Northeast Georgia Intrastate Air Quality Control Region. The Northeast Georgia Intrastate Air Quality Control Region consists of the territorial area encompassed by the...
40 CFR 81.251 - Northeast Kansas Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Northeast Kansas Intrastate Air... Air Quality Control Regions § 81.251 Northeast Kansas Intrastate Air Quality Control Region. The Northeast Kansas Intrastate Air Quality Control Region consists of the territorial area encompassed by the...
40 CFR 81.55 - Northeast Pennsylvania-Upper Delaware Valley Interstate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Northeast Pennsylvania-Upper Delaware... Designation of Air Quality Control Regions § 81.55 Northeast Pennsylvania-Upper Delaware Valley Interstate Air Quality Control Region. The Northeast Pennsylvania-Upper Delaware Valley Interstate Air Quality Control...
40 CFR 81.256 - Northeast Iowa Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Northeast Iowa Intrastate Air Quality Control Region. 81.256 Section 81.256 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... Quality Control Regions § 81.256 Northeast Iowa Intrastate Air Quality Control Region. The Northeast Iowa...
40 CFR 81.139 - Northeast Arkansas Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Northeast Arkansas Intrastate Air... Air Quality Control Regions § 81.139 Northeast Arkansas Intrastate Air Quality Control Region. The Northeast Arkansas Intrastate Air Quality Control Region consists of the territorial area encompassed by the...
40 CFR 81.158 - Southern Wisconsin Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Southern Wisconsin Intrastate Air... Air Quality Control Regions § 81.158 Southern Wisconsin Intrastate Air Quality Control Region. The Southern Wisconsin Intrastate Air Quality Control Region consists of the territorial area encompassed by...
40 CFR 81.157 - North Central Wisconsin Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 18 2012-07-01 2012-07-01 false North Central Wisconsin Intrastate Air... Air Quality Control Regions § 81.157 North Central Wisconsin Intrastate Air Quality Control Region. The North Central Wisconsin Intrastate Air Quality Control Region consists of the territorial area...
40 CFR 81.158 - Southern Wisconsin Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Southern Wisconsin Intrastate Air... Air Quality Control Regions § 81.158 Southern Wisconsin Intrastate Air Quality Control Region. The Southern Wisconsin Intrastate Air Quality Control Region consists of the territorial area encompassed by...
40 CFR 81.158 - Southern Wisconsin Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Southern Wisconsin Intrastate Air... Air Quality Control Regions § 81.158 Southern Wisconsin Intrastate Air Quality Control Region. The Southern Wisconsin Intrastate Air Quality Control Region consists of the territorial area encompassed by...
40 CFR 81.158 - Southern Wisconsin Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Southern Wisconsin Intrastate Air... Air Quality Control Regions § 81.158 Southern Wisconsin Intrastate Air Quality Control Region. The Southern Wisconsin Intrastate Air Quality Control Region consists of the territorial area encompassed by...
40 CFR 81.158 - Southern Wisconsin Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Southern Wisconsin Intrastate Air... Air Quality Control Regions § 81.158 Southern Wisconsin Intrastate Air Quality Control Region. The Southern Wisconsin Intrastate Air Quality Control Region consists of the territorial area encompassed by...
40 CFR 81.157 - North Central Wisconsin Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 18 2013-07-01 2013-07-01 false North Central Wisconsin Intrastate Air... Air Quality Control Regions § 81.157 North Central Wisconsin Intrastate Air Quality Control Region. The North Central Wisconsin Intrastate Air Quality Control Region consists of the territorial area...
40 CFR 81.157 - North Central Wisconsin Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false North Central Wisconsin Intrastate Air... Air Quality Control Regions § 81.157 North Central Wisconsin Intrastate Air Quality Control Region. The North Central Wisconsin Intrastate Air Quality Control Region consists of the territorial area...
40 CFR 81.157 - North Central Wisconsin Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 18 2014-07-01 2014-07-01 false North Central Wisconsin Intrastate Air... Air Quality Control Regions § 81.157 North Central Wisconsin Intrastate Air Quality Control Region. The North Central Wisconsin Intrastate Air Quality Control Region consists of the territorial area...
40 CFR 81.157 - North Central Wisconsin Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 17 2011-07-01 2011-07-01 false North Central Wisconsin Intrastate Air... Air Quality Control Regions § 81.157 North Central Wisconsin Intrastate Air Quality Control Region. The North Central Wisconsin Intrastate Air Quality Control Region consists of the territorial area...
40 CFR 81.134 - Austin-Waco Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Austin-Waco Intrastate Air Quality Control Region. 81.134 Section 81.134 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... Quality Control Regions § 81.134 Austin-Waco Intrastate Air Quality Control Region. The Austin-Waco...
40 CFR 81.134 - Austin-Waco Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Austin-Waco Intrastate Air Quality Control Region. 81.134 Section 81.134 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... Quality Control Regions § 81.134 Austin-Waco Intrastate Air Quality Control Region. The Austin-Waco...
40 CFR 81.134 - Austin-Waco Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Austin-Waco Intrastate Air Quality Control Region. 81.134 Section 81.134 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... Quality Control Regions § 81.134 Austin-Waco Intrastate Air Quality Control Region. The Austin-Waco...
40 CFR 81.134 - Austin-Waco Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Austin-Waco Intrastate Air Quality Control Region. 81.134 Section 81.134 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... Quality Control Regions § 81.134 Austin-Waco Intrastate Air Quality Control Region. The Austin-Waco...
40 CFR 81.102 - Metropolitan Quad Cities Interstate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Metropolitan Quad Cities Interstate... Designation of Air Quality Control Regions § 81.102 Metropolitan Quad Cities Interstate Air Quality Control Region. The Metropolitan Quad Cities Interstate Air Quality Control Region (Illinois-Iowa) consists of...
40 CFR 81.170 - Miles City Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Miles City Intrastate Air Quality Control Region. 81.170 Section 81.170 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... Quality Control Regions § 81.170 Miles City Intrastate Air Quality Control Region. The Miles City...
40 CFR 81.170 - Miles City Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Miles City Intrastate Air Quality Control Region. 81.170 Section 81.170 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... Quality Control Regions § 81.170 Miles City Intrastate Air Quality Control Region. The Miles City...
40 CFR 81.102 - Metropolitan Quad Cities Interstate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Metropolitan Quad Cities Interstate... Designation of Air Quality Control Regions § 81.102 Metropolitan Quad Cities Interstate Air Quality Control Region. The Metropolitan Quad Cities Interstate Air Quality Control Region (Illinois-Iowa) consists of...
40 CFR 81.25 - Metropolitan Kansas City Interstate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Metropolitan Kansas City Interstate... Designation of Air Quality Control Regions § 81.25 Metropolitan Kansas City Interstate Air Quality Control Region. The Metropolitan Kansas City Interstate Air Quality Control Region (Missouri-Kansas) consists of...
40 CFR 81.25 - Metropolitan Kansas City Interstate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Metropolitan Kansas City Interstate... Designation of Air Quality Control Regions § 81.25 Metropolitan Kansas City Interstate Air Quality Control Region. The Metropolitan Kansas City Interstate Air Quality Control Region (Missouri-Kansas) consists of...
46 CFR 164.120-11 - Production quality control requirements.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 46 Shipping 6 2014-10-01 2014-10-01 false Production quality control requirements. 164.120-11... Rescue Boats § 164.120-11 Production quality control requirements. The resin manufacturer must institute a quality control procedure to ensure that all Coast Guard-accepted resin is produced to the same...
46 CFR 164.120-11 - Production quality control requirements.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 46 Shipping 6 2012-10-01 2012-10-01 false Production quality control requirements. 164.120-11... Rescue Boats § 164.120-11 Production quality control requirements. The resin manufacturer must institute a quality control procedure to ensure that all Coast Guard-accepted resin is produced to the same...
46 CFR 164.120-11 - Production quality control requirements.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 46 Shipping 6 2013-10-01 2013-10-01 false Production quality control requirements. 164.120-11... Rescue Boats § 164.120-11 Production quality control requirements. The resin manufacturer must institute a quality control procedure to ensure that all Coast Guard-accepted resin is produced to the same...
40 CFR 81.134 - Austin-Waco Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Austin-Waco Intrastate Air Quality Control Region. 81.134 Section 81.134 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... Quality Control Regions § 81.134 Austin-Waco Intrastate Air Quality Control Region. The Austin-Waco...
Implementing self sustained quality control procedures in a clinical laboratory.
Khatri, Roshan; K C, Sanjay; Shrestha, Prabodh; Sinha, J N
2013-01-01
Quality control is an essential component in every clinical laboratory which maintains the excellence of laboratory standards, supplementing to proper disease diagnosis, patient care and resulting in overall strengthening of health care system. Numerous quality control schemes are available, with combinations of procedures, most of which are tedious, time consuming and can be "too technical" whereas commercially available quality control materials can be expensive especially for laboratories in developing nations like Nepal. Here, we present a procedure performed at our centre with self prepared control serum and use of simple statistical tools for quality assurance. The pooled serum was prepared as per guidelines for preparation of stabilized liquid quality control serum from human sera. Internal Quality Assessment was performed on this sample, on a daily basis which included measurement of 12 routine biochemical parameters. The results were plotted on Levey-Jennings charts and analysed with quality control rules, for a period of one month. The mean levels of biochemical analytes in self prepared control serum were within normal physiological range. This serum was evaluated every day along with patients' samples. The results obtained were plotted on control charts and analysed using common quality control rules to identify possible systematic and random errors. Immediate mitigation measures were taken and the dispatch of erroneous reports was avoided. In this study we try to highlight on a simple internal quality control procedure which can be performed by laboratories, with minimum technology, expenditure, and expertise and improve reliability and validity of the test reports.
Jin, Huang; Chun-Lian, Tang; Zu-Wu, Tu; Li, Tang; Ke-Hui, Zhang; Qian, Li; Jun, Ye
2018-04-18
To prepare freeze-drying control materials of IgG antibody against Schistosoma japonicum for detection kits. The serum samples of schistosomiasis patients from endemic areas and normal people without history of schistosome infection or contact with infested water in Hubei Province were collected. All the sera were detected by the method approved by China Food and Drug Administration and selected for preparation of quality control samples. Totally twelve positive quality control materials, ten negative quality control materials, and one sensitive and one precision quality control materials were screened. According to the positive serum level, the positive degrees of quality control materials were divided into strong, medium and weak levels. The stability could be valid for one year. The freeze-drying quality control materials of IgG antibody against S. japonicum for detection kits are prepared. They are easy to use and have good stability, and therefore, they may meet the requirement of quality control for the detection of schistosomiasis diagnostics kits.
7 CFR 58.141 - Alternate quality control program.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 7 Agriculture 3 2011-01-01 2011-01-01 false Alternate quality control program. 58.141 Section 58... Service 1 Quality Specifications for Raw Milk § 58.141 Alternate quality control program. When a plant has in operation an acceptable quality program, at the producer level, which is approved by the...
40 CFR 81.32 - Puget Sound Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Puget Sound Intrastate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.32 Puget Sound Intrastate Air Quality Control Region. The Puget Sound...
40 CFR 81.80 - Las Vegas Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Las Vegas Intrastate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.80 Las Vegas Intrastate Air Quality Control Region. The Las Vegas Intrastate...
40 CFR 81.52 - Wasatch Front Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Wasatch Front Intrastate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.52 Wasatch Front Intrastate Air Quality Control Region. The Wasatch Front...
40 CFR 81.54 - Cook Inlet Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Cook Inlet Intrastate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.54 Cook Inlet Intrastate Air Quality Control Region. The Cook Inlet...
40 CFR 81.32 - Puget Sound Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Puget Sound Intrastate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.32 Puget Sound Intrastate Air Quality Control Region. The Puget Sound...
40 CFR 81.67 - Lake Michigan Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Lake Michigan Intrastate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.67 Lake Michigan Intrastate Air Quality Control Region. The Menominee...
40 CFR 81.52 - Wasatch Front Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Wasatch Front Intrastate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.52 Wasatch Front Intrastate Air Quality Control Region. The Wasatch Front...
40 CFR 81.17 - Metropolitan Los Angeles Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Metropolitan Los Angeles Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.17 Metropolitan Los Angeles Air Quality Control Region. The Metropolitan Los...
40 CFR 81.54 - Cook Inlet Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Cook Inlet Intrastate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.54 Cook Inlet Intrastate Air Quality Control Region. The Cook Inlet...
40 CFR 81.67 - Lake Michigan Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Lake Michigan Intrastate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.67 Lake Michigan Intrastate Air Quality Control Region. The Menominee...
40 CFR 81.54 - Cook Inlet Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Cook Inlet Intrastate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.54 Cook Inlet Intrastate Air Quality Control Region. The Cook Inlet...
40 CFR 81.52 - Wasatch Front Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Wasatch Front Intrastate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.52 Wasatch Front Intrastate Air Quality Control Region. The Wasatch Front...
40 CFR 81.17 - Metropolitan Los Angeles Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Metropolitan Los Angeles Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.17 Metropolitan Los Angeles Air Quality Control Region. The Metropolitan Los...
40 CFR 81.67 - Lake Michigan Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Lake Michigan Intrastate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.67 Lake Michigan Intrastate Air Quality Control Region. The Menominee...
40 CFR 81.52 - Wasatch Front Intrastate Air Quality Control Region.
Code of Federal Regulations, 2011 CFR
2011-07-01
... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Wasatch Front Intrastate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.52 Wasatch Front Intrastate Air Quality Control Region. The Wasatch Front...
40 CFR 81.32 - Puget Sound Intrastate Air Quality Control Region.
Code of Federal Regulations, 2012 CFR
2012-07-01
... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Puget Sound Intrastate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.32 Puget Sound Intrastate Air Quality Control Region. The Puget Sound...
40 CFR 81.32 - Puget Sound Intrastate Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Puget Sound Intrastate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.32 Puget Sound Intrastate Air Quality Control Region. The Puget Sound...
40 CFR 81.17 - Metropolitan Los Angeles Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Metropolitan Los Angeles Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.17 Metropolitan Los Angeles Air Quality Control Region. The Metropolitan Los...
40 CFR 81.17 - Metropolitan Los Angeles Air Quality Control Region.
Code of Federal Regulations, 2013 CFR
2013-07-01
... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Metropolitan Los Angeles Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.17 Metropolitan Los Angeles Air Quality Control Region. The Metropolitan Los...
40 CFR 81.54 - Cook Inlet Intrastate Air Quality Control Region.
Code of Federal Regulations, 2014 CFR
2014-07-01
... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Cook Inlet Intrastate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.54 Cook Inlet Intrastate Air Quality Control Region. The Cook Inlet...
40 CFR 81.17 - Metropolitan Los Angeles Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Metropolitan Los Angeles Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.17 Metropolitan Los Angeles Air Quality Control Region. The Metropolitan Los...
40 CFR 81.52 - Wasatch Front Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Wasatch Front Intrastate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.52 Wasatch Front Intrastate Air Quality Control Region. The Wasatch Front...
40 CFR 81.67 - Lake Michigan Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Lake Michigan Intrastate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.67 Lake Michigan Intrastate Air Quality Control Region. The Menominee...
40 CFR 81.32 - Puget Sound Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Puget Sound Intrastate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.32 Puget Sound Intrastate Air Quality Control Region. The Puget Sound...
40 CFR 81.54 - Cook Inlet Intrastate Air Quality Control Region.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Cook Inlet Intrastate Air Quality...) AIR PROGRAMS (CONTINUED) DESIGNATION OF AREAS FOR AIR QUALITY PLANNING PURPOSES Designation of Air Quality Control Regions § 81.54 Cook Inlet Intrastate Air Quality Control Region. The Cook Inlet...
Control by quality: proposition of a typology.
Pujo, P; Pillet, M
The application of Quality tools and methods in industrial management has always had a fundamental impact on the control of production. It influences the behavior of the actors concerned, while introducing the necessary notions and formalizations, especially for production systems with little or no automation, which constitute a large part of the industrial activity. Several quality approaches are applied in the workshop and are implemented at the level of the control. In this paper, the authors present a typology of the various approaches that have successively influenced control, such as statistical process control, quality assurance, and continuous improvement. First the authors present a parallel between production control and quality organizational structure. They note the duality between control, which is aimed at increasing productivity, and quality, which aims to satisfy the needs of the customer. They also note the hierarchical organizational structure of these two systems of management with, at each level, the notion of a feedback loop. This notion is fundamental to any kind of decision making. The paper is organized around the operational, tactical, and strategic levels, by describing for each level the main methods and tools for control by quality. The overview of these tools and methods starts at the operational level, with the Statistical Process Control, the Taguchi technique, and the "six sigma" approach. On the tactical level, we find a quality system approach, with a documented description of the procedures introduced in the firm. The management system can refer here to Quality Assurance, Total Productive Maintenance, or Management by Total Quality. The formalization through procedures of the rules of decision governing the process control enhances the validity of these rules. This leads to the enhancement of their reliability and to their consolidation. All this counterbalances the human, intrinsically fluctuating, behavior of the control operators. Strategic control by quality is then detailed, and the two main approaches, the continuous improvement approach and the proactive improvement approach, are introduced. Finally, the authors observe that at each of the three levels, the continuous process improvement, which is a component of Total Quality, becomes an essential preoccupation for the control. Ultimately, the recursive utilization of the Deming cycle remains the best practice for the control by quality.
Contributions of CCLM to advances in quality control.
Kazmierczak, Steven C
2013-01-01
Abstract The discipline of laboratory medicine is relatively young when considered in the context of the history of medicine itself. The history of quality control, within the context of laboratory medicine, also enjoys a relatively brief, but rich history. Laboratory quality control continues to evolve along with advances in automation, measurement techniques and information technology. Clinical Chemistry and Laboratory Medicine (CCLM) has played a key role in helping disseminate information about the proper use and utility of quality control. Publication of important advances in quality control techniques and dissemination of guidelines concerned with laboratory quality control has undoubtedly helped readers of this journal keep up to date on the most recent developments in this field.
Gu, Jun-Fei; Feng, Liang; Zhang, Ming-Hua; Wu, Chan; Jia, Xiao-Bin
2013-11-01
Safety is an important component of the quality control of traditional Chinese medicine (TCM) preparation products, as well as an important guarantee for clinical application. Currently, the quality control of TCMs in Chinese Pharmacopoeia mostly focuses on indicative compounds for TCM efficacy. TCM preparations are associated with multiple links, from raw materials to products, and each procedure may have impacts on the safety of preparation. We make a summary and analysis on the factors impacting safety during the preparation of TCM products, and then expound the important role of the "multi-dimensional structure and process dynamic quality control technology system" in the quality safety of TCM preparations. Because the product quality of TCM preparation is closely related to the safety, the control over safety-related material basis is an important component of the product quality control of TCM preparations. The implementation of the quality control over the dynamic process of TCM preparations from raw materials to products, and the improvement of the TCM quality safety control at the microcosmic level help lay a firm foundation for the development of the modernization process of TCM preparations.
46 CFR 160.115-15 - Production inspections, tests, quality control, and conformance of winches.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 46 Shipping 6 2013-10-01 2013-10-01 false Production inspections, tests, quality control, and... Launching Appliances-Winches § 160.115-15 Production inspections, tests, quality control, and conformance of... necessary to maintain quality control and to monitor compliance with the requirements of this subpart. (b...
46 CFR 160.115-15 - Production inspections, tests, quality control, and conformance of winches.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 46 Shipping 6 2014-10-01 2014-10-01 false Production inspections, tests, quality control, and... Launching Appliances-Winches § 160.115-15 Production inspections, tests, quality control, and conformance of... necessary to maintain quality control and to monitor compliance with the requirements of this subpart. (b...
46 CFR 160.132-15 - Production inspections, tests, quality control, and conformance of davits.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 46 Shipping 6 2013-10-01 2013-10-01 false Production inspections, tests, quality control, and... Launching Appliances-Davits § 160.132-15 Production inspections, tests, quality control, and conformance of... necessary to maintain quality control and to monitor compliance with the requirements of this subpart. (b...