Sample records for quantifying information transfer

  1. Quantifying transfer after perceptual-motor sequence learning: how inflexible is implicit learning?

    PubMed

    Sanchez, Daniel J; Yarnik, Eric N; Reber, Paul J

    2015-03-01

    Studies of implicit perceptual-motor sequence learning have often shown learning to be inflexibly tied to the training conditions during learning. Since sequence learning is seen as a model task of skill acquisition, limits on the ability to transfer knowledge from the training context to a performance context indicates important constraints on skill learning approaches. Lack of transfer across contexts has been demonstrated by showing that when task elements are changed following training, this leads to a disruption in performance. These results have typically been taken as suggesting that the sequence knowledge relies on integrated representations across task elements (Abrahamse, Jiménez, Verwey, & Clegg, Psychon Bull Rev 17:603-623, 2010a). Using a relatively new sequence learning task, serial interception sequence learning, three experiments are reported that quantify this magnitude of performance disruption after selectively manipulating individual aspects of motor performance or perceptual information. In Experiment 1, selective disruption of the timing or order of sequential actions was examined using a novel response manipulandum that allowed for separate analysis of these two motor response components. In Experiments 2 and 3, transfer was examined after selective disruption of perceptual information that left the motor response sequence intact. All three experiments provided quantifiable estimates of partial transfer to novel contexts that suggest some level of information integration across task elements. However, the ability to identify quantifiable levels of successful transfer indicates that integration is not all-or-none and that measurement sensitivity is a key in understanding sequence knowledge representations.

  2. Quantifying transfer after perceptual-motor sequence learning: how inflexible is implicit learning?

    PubMed Central

    Sanchez, Daniel J.; Yarnik, Eric N.

    2015-01-01

    Studies of implicit perceptual-motor sequence learning have often shown learning to be inflexibly tied to the training conditions during learning. Since sequence learning is seen as a model task of skill acquisition, limits on the ability to transfer knowledge from the training context to a performance context indicates important constraints on skill learning approaches. Lack of transfer across contexts has been demonstrated by showing that when task elements are changed following training, this leads to a disruption in performance. These results have typically been taken as suggesting that the sequence knowledge relies on integrated representations across task elements (Abrahamse, Jiménez, Verwey, & Clegg, Psychon Bull Rev 17:603–623, 2010a). Using a relatively new sequence learning task, serial interception sequence learning, three experiments are reported that quantify this magnitude of performance disruption after selectively manipulating individual aspects of motor performance or perceptual information. In Experiment 1, selective disruption of the timing or order of sequential actions was examined using a novel response manipulandum that allowed for separate analysis of these two motor response components. In Experiments 2 and 3, transfer was examined after selective disruption of perceptual information that left the motor response sequence intact. All three experiments provided quantifiable estimates of partial transfer to novel contexts that suggest some level of information integration across task elements. However, the ability to identify quantifiable levels of successful transfer indicates that integration is not all-or-none and that measurement sensitivity is a key in understanding sequence knowledge representations. PMID:24668505

  3. Information transfer satellite concept study. Volume 3: Appendices

    NASA Technical Reports Server (NTRS)

    Bergin, P.; Kincade, C.; Kurpiewski, D.; Leinhaupel, F.; Millican, F.; Onstad, R.

    1971-01-01

    Briefly reviewed are the various documents which supply background information for the information transfer satellite study. The sixteen papers reviewed are evaluated in terms of: (1) the category of service or demand being treated; (2) the extent to which information transfer predictions are quantified; (3) the degree to which the data supplied is adequate for the purposes of system synthesis; (4) some assessment as to the overall utility of the data presented in the paper.

  4. Entropy Transfer between Residue Pairs and Allostery in Proteins: Quantifying Allosteric Communication in Ubiquitin.

    PubMed

    Hacisuleyman, Aysima; Erman, Burak

    2017-01-01

    It has recently been proposed by Gunasakaran et al. that allostery may be an intrinsic property of all proteins. Here, we develop a computational method that can determine and quantify allosteric activity in any given protein. Based on Schreiber's transfer entropy formulation, our approach leads to an information transfer landscape for the protein that shows the presence of entropy sinks and sources and explains how pairs of residues communicate with each other using entropy transfer. The model can identify the residues that drive the fluctuations of others. We apply the model to Ubiquitin, whose allosteric activity has not been emphasized until recently, and show that there are indeed systematic pathways of entropy and information transfer between residues that correlate well with the activities of the protein. We use 600 nanosecond molecular dynamics trajectories for Ubiquitin and its complex with human polymerase iota and evaluate entropy transfer between all pairs of residues of Ubiquitin and quantify the binding susceptibility changes upon complex formation. We explain the complex formation propensities of Ubiquitin in terms of entropy transfer. Important residues taking part in allosteric communication in Ubiquitin predicted by our approach are in agreement with results of NMR relaxation dispersion experiments. Finally, we show that time delayed correlation of fluctuations of two interacting residues possesses an intrinsic causality that tells which residue controls the interaction and which one is controlled. Our work shows that time delayed correlations, entropy transfer and causality are the required new concepts for explaining allosteric communication in proteins.

  5. Entropy Transfer between Residue Pairs and Allostery in Proteins: Quantifying Allosteric Communication in Ubiquitin

    PubMed Central

    2017-01-01

    It has recently been proposed by Gunasakaran et al. that allostery may be an intrinsic property of all proteins. Here, we develop a computational method that can determine and quantify allosteric activity in any given protein. Based on Schreiber's transfer entropy formulation, our approach leads to an information transfer landscape for the protein that shows the presence of entropy sinks and sources and explains how pairs of residues communicate with each other using entropy transfer. The model can identify the residues that drive the fluctuations of others. We apply the model to Ubiquitin, whose allosteric activity has not been emphasized until recently, and show that there are indeed systematic pathways of entropy and information transfer between residues that correlate well with the activities of the protein. We use 600 nanosecond molecular dynamics trajectories for Ubiquitin and its complex with human polymerase iota and evaluate entropy transfer between all pairs of residues of Ubiquitin and quantify the binding susceptibility changes upon complex formation. We explain the complex formation propensities of Ubiquitin in terms of entropy transfer. Important residues taking part in allosteric communication in Ubiquitin predicted by our approach are in agreement with results of NMR relaxation dispersion experiments. Finally, we show that time delayed correlation of fluctuations of two interacting residues possesses an intrinsic causality that tells which residue controls the interaction and which one is controlled. Our work shows that time delayed correlations, entropy transfer and causality are the required new concepts for explaining allosteric communication in proteins. PMID:28095404

  6. Interactions of information transfer along separable causal paths

    NASA Astrophysics Data System (ADS)

    Jiang, Peishi; Kumar, Praveen

    2018-04-01

    Complex systems arise as a result of interdependences between multiple variables, whose causal interactions can be visualized in a time-series graph. Transfer entropy and information partitioning approaches have been used to characterize such dependences. However, these approaches capture net information transfer occurring through a multitude of pathways involved in the interaction and as a result mask our ability to discern the causal interaction within a subgraph of interest through specific pathways. We build on recent developments of momentary information transfer along causal paths proposed by Runge [Phys. Rev. E 92, 062829 (2015), 10.1103/PhysRevE.92.062829] to develop a framework for quantifying information partitioning along separable causal paths. Momentary information transfer along causal paths captures the amount of information transfer between any two variables lagged at two specific points in time. Our approach expands this concept to characterize the causal interaction in terms of synergistic, unique, and redundant information transfer through separable causal paths. Through a graphical model, we analyze the impact of the separable and nonseparable causal paths and the causality structure embedded in the graph as well as the noise effect on information partitioning by using synthetic data generated from two coupled logistic equation models. Our approach can provide a valuable reference for an autonomous information partitioning along separable causal paths which form a causal subgraph influencing a target.

  7. Backward transfer entropy: Informational measure for detecting hidden Markov models and its interpretations in thermodynamics, gambling and causality

    PubMed Central

    Ito, Sosuke

    2016-01-01

    The transfer entropy is a well-established measure of information flow, which quantifies directed influence between two stochastic time series and has been shown to be useful in a variety fields of science. Here we introduce the transfer entropy of the backward time series called the backward transfer entropy, and show that the backward transfer entropy quantifies how far it is from dynamics to a hidden Markov model. Furthermore, we discuss physical interpretations of the backward transfer entropy in completely different settings of thermodynamics for information processing and the gambling with side information. In both settings of thermodynamics and the gambling, the backward transfer entropy characterizes a possible loss of some benefit, where the conventional transfer entropy characterizes a possible benefit. Our result implies the deep connection between thermodynamics and the gambling in the presence of information flow, and that the backward transfer entropy would be useful as a novel measure of information flow in nonequilibrium thermodynamics, biochemical sciences, economics and statistics. PMID:27833120

  8. Backward transfer entropy: Informational measure for detecting hidden Markov models and its interpretations in thermodynamics, gambling and causality

    NASA Astrophysics Data System (ADS)

    Ito, Sosuke

    2016-11-01

    The transfer entropy is a well-established measure of information flow, which quantifies directed influence between two stochastic time series and has been shown to be useful in a variety fields of science. Here we introduce the transfer entropy of the backward time series called the backward transfer entropy, and show that the backward transfer entropy quantifies how far it is from dynamics to a hidden Markov model. Furthermore, we discuss physical interpretations of the backward transfer entropy in completely different settings of thermodynamics for information processing and the gambling with side information. In both settings of thermodynamics and the gambling, the backward transfer entropy characterizes a possible loss of some benefit, where the conventional transfer entropy characterizes a possible benefit. Our result implies the deep connection between thermodynamics and the gambling in the presence of information flow, and that the backward transfer entropy would be useful as a novel measure of information flow in nonequilibrium thermodynamics, biochemical sciences, economics and statistics.

  9. Effective field theory models for nonviolent information transfer from black holes

    NASA Astrophysics Data System (ADS)

    Giddings, Steven B.; Shi, Yinbo

    2014-06-01

    Transfer of quantum information from the interior of a black hole to its atmosphere is described, in models based on effective field theory. This description illustrates that such transfer need not be violent to the semiclassical geometry or to infalling observers, and in particular can avoid producing a singular horizon or "firewall". One can specifically quantify the rate of information transfer and show that a rate necessary to unitarize black hole evaporation produces a relatively mild modification to the stress tensor near the horizon. In an exterior description of the transfer, the new interactions responsible for it are approximated by "effective sources" acting on fields in the black hole atmosphere. If the necessary interactions couple to general modes in the black hole atmosphere, one also finds a straightforward mechanism for information transfer rates to increase when a black hole is mined, avoiding paradoxical behavior. Correspondence limits are discussed, in the presence of such new interactions, for both small black holes and large ones; the near-horizon description of the latter is approximately that of Rindler space.

  10. Empirical and Theoretical Aspects of Generation and Transfer of Information in a Neuromagnetic Source Network

    PubMed Central

    Vakorin, Vasily A.; Mišić, Bratislav; Krakovska, Olga; McIntosh, Anthony Randal

    2011-01-01

    Variability in source dynamics across the sources in an activated network may be indicative of how the information is processed within a network. Information-theoretic tools allow one not only to characterize local brain dynamics but also to describe interactions between distributed brain activity. This study follows such a framework and explores the relations between signal variability and asymmetry in mutual interdependencies in a data-driven pipeline of non-linear analysis of neuromagnetic sources reconstructed from human magnetoencephalographic (MEG) data collected as a reaction to a face recognition task. Asymmetry in non-linear interdependencies in the network was analyzed using transfer entropy, which quantifies predictive information transfer between the sources. Variability of the source activity was estimated using multi-scale entropy, quantifying the rate of which information is generated. The empirical results are supported by an analysis of synthetic data based on the dynamics of coupled systems with time delay in coupling. We found that the amount of information transferred from one source to another was correlated with the difference in variability between the dynamics of these two sources, with the directionality of net information transfer depending on the time scale at which the sample entropy was computed. The results based on synthetic data suggest that both time delay and strength of coupling can contribute to the relations between variability of brain signals and information transfer between them. Our findings support the previous attempts to characterize functional organization of the activated brain, based on a combination of non-linear dynamics and temporal features of brain connectivity, such as time delay. PMID:22131968

  11. Quantifying highly efficient incoherent energy transfer in perylene-based multichromophore arrays.

    PubMed

    Webb, James E A; Chen, Kai; Prasad, Shyamal K K; Wojciechowski, Jonathan P; Falber, Alexander; Thordarson, Pall; Hodgkiss, Justin M

    2016-01-21

    Multichromophore perylene arrays were designed and synthesized to have extremely efficient resonance energy transfer. Using broadband ultrafast photoluminescence and transient absorption spectroscopies, transfer timescales of approximately 1 picosecond were resolved, corresponding to efficiencies of up to 99.98%. The broadband measurements also revealed spectra corresponding to incoherent transfer between localized states. Polarization resolved spectroscopy was used to measure the dipolar angles between donor and acceptor chromophores, thereby enabling geometric factors to be fixed when assessing the validity of Förster theory in this regime. Förster theory was found to predict the correct magnitude of transfer rates, with measured ∼2-fold deviations consistent with the breakdown of the point-dipole approximation at close approach. The materials presented, along with the novel methods for quantifying ultrahigh energy transfer efficiencies, will be valuable for applications demanding extremely efficient energy transfer, including fluorescent solar concentrators, optical gain, and photonic logic devices.

  12. Quantifying the Interactions between Maternal and Fetal Heart Rates by Transfer Entropy.

    PubMed

    Marzbanrad, Faezeh; Kimura, Yoshitaka; Palaniswami, Marimuthu; Khandoker, Ahsan H

    2015-01-01

    Evidence of the short term relationship between maternal and fetal heart rates has been found in previous studies. However there is still limited knowledge about underlying mechanisms and patterns of the coupling throughout gestation. In this study, Transfer Entropy (TE) was used to quantify directed interactions between maternal and fetal heart rates at various time delays and gestational ages. Experimental results using maternal and fetal electrocardiograms showed significant coupling for 63 out of 65 fetuses, by statistically validating against surrogate pairs. Analysis of TE showed a decrease in transfer of information from fetus to the mother with gestational age, alongside the maturation of the fetus. On the other hand, maternal to fetal TE was significantly greater in mid (26-31 weeks) and late (32-41 weeks) gestation compared to early (16-25 weeks) gestation (Mann Whitney Wilcoxon (MWW) p<0.05). TE further increased from mid to late, for the fetuses with RMSSD of fetal heart rate being larger than 4 msec in the late gestation. This difference was not observed for the fetuses with smaller RMSSD, which could be associated with the quiet sleep state. Delay in the information transfer from mother to fetus significantly decreased (p = 0.03) from mid to late gestation, implying a decrease in fetal response time. These changes occur concomitant with the maturation of the fetal sensory and autonomic nervous systems with advancing gestational age. The effect of maternal respiratory rate derived from maternal ECG was also investigated and no significant relationship was found between breathing rate and TE at any lag. In conclusion, the application of TE with delays revealed detailed information on the fetal-maternal heart rate coupling strength and latency throughout gestation, which could provide novel clinical markers of fetal development and well-being.

  13. Quantifying the Interactions between Maternal and Fetal Heart Rates by Transfer Entropy

    PubMed Central

    Marzbanrad, Faezeh; Kimura, Yoshitaka; Palaniswami, Marimuthu; Khandoker, Ahsan H.

    2015-01-01

    Evidence of the short term relationship between maternal and fetal heart rates has been found in previous studies. However there is still limited knowledge about underlying mechanisms and patterns of the coupling throughout gestation. In this study, Transfer Entropy (TE) was used to quantify directed interactions between maternal and fetal heart rates at various time delays and gestational ages. Experimental results using maternal and fetal electrocardiograms showed significant coupling for 63 out of 65 fetuses, by statistically validating against surrogate pairs. Analysis of TE showed a decrease in transfer of information from fetus to the mother with gestational age, alongside the maturation of the fetus. On the other hand, maternal to fetal TE was significantly greater in mid (26–31 weeks) and late (32–41 weeks) gestation compared to early (16–25 weeks) gestation (Mann Whitney Wilcoxon (MWW) p<0.05). TE further increased from mid to late, for the fetuses with RMSSD of fetal heart rate being larger than 4 msec in the late gestation. This difference was not observed for the fetuses with smaller RMSSD, which could be associated with the quiet sleep state. Delay in the information transfer from mother to fetus significantly decreased (p = 0.03) from mid to late gestation, implying a decrease in fetal response time. These changes occur concomitant with the maturation of the fetal sensory and autonomic nervous systems with advancing gestational age. The effect of maternal respiratory rate derived from maternal ECG was also investigated and no significant relationship was found between breathing rate and TE at any lag. In conclusion, the application of TE with delays revealed detailed information on the fetal-maternal heart rate coupling strength and latency throughout gestation, which could provide novel clinical markers of fetal development and well-being. PMID:26701122

  14. Quantifying quantum coherence with quantum Fisher information.

    PubMed

    Feng, X N; Wei, L F

    2017-11-14

    Quantum coherence is one of the old but always important concepts in quantum mechanics, and now it has been regarded as a necessary resource for quantum information processing and quantum metrology. However, the question of how to quantify the quantum coherence has just been paid the attention recently (see, e.g., Baumgratz et al. PRL, 113. 140401 (2014)). In this paper we verify that the well-known quantum Fisher information (QFI) can be utilized to quantify the quantum coherence, as it satisfies the monotonicity under the typical incoherent operations and the convexity under the mixing of the quantum states. Differing from most of the pure axiomatic methods, quantifying quantum coherence by QFI could be experimentally testable, as the bound of the QFI is practically measurable. The validity of our proposal is specifically demonstrated with the typical phase-damping and depolarizing evolution processes of a generic single-qubit state, and also by comparing it with the other quantifying methods proposed previously.

  15. Rényi’s information transfer between financial time series

    NASA Astrophysics Data System (ADS)

    Jizba, Petr; Kleinert, Hagen; Shefaat, Mohammad

    2012-05-01

    In this paper, we quantify the statistical coherence between financial time series by means of the Rényi entropy. With the help of Campbell’s coding theorem, we show that the Rényi entropy selectively emphasizes only certain sectors of the underlying empirical distribution while strongly suppressing others. This accentuation is controlled with Rényi’s parameter q. To tackle the issue of the information flow between time series, we formulate the concept of Rényi’s transfer entropy as a measure of information that is transferred only between certain parts of underlying distributions. This is particularly pertinent in financial time series, where the knowledge of marginal events such as spikes or sudden jumps is of a crucial importance. We apply the Rényian information flow to stock market time series from 11 world stock indices as sampled at a daily rate in the time period 02.01.1990-31.12.2009. Corresponding heat maps and net information flows are represented graphically. A detailed discussion of the transfer entropy between the DAX and S&P500 indices based on minute tick data gathered in the period 02.04.2008-11.09.2009 is also provided. Our analysis shows that the bivariate information flow between world markets is strongly asymmetric with a distinct information surplus flowing from the Asia-Pacific region to both European and US markets. An important yet less dramatic excess of information also flows from Europe to the US. This is particularly clearly seen from a careful analysis of Rényi information flow between the DAX and S&P500 indices.

  16. Information Flows? A Critique of Transfer Entropies

    NASA Astrophysics Data System (ADS)

    James, Ryan G.; Barnett, Nix; Crutchfield, James P.

    2016-06-01

    A central task in analyzing complex dynamics is to determine the loci of information storage and the communication topology of information flows within a system. Over the last decade and a half, diagnostics for the latter have come to be dominated by the transfer entropy. Via straightforward examples, we show that it and a derivative quantity, the causation entropy, do not, in fact, quantify the flow of information. At one and the same time they can overestimate flow or underestimate influence. We isolate why this is the case and propose several avenues to alternate measures for information flow. We also address an auxiliary consequence: The proliferation of networks as a now-common theoretical model for large-scale systems, in concert with the use of transferlike entropies, has shoehorned dyadic relationships into our structural interpretation of the organization and behavior of complex systems. This interpretation thus fails to include the effects of polyadic dependencies. The net result is that much of the sophisticated organization of complex systems may go undetected.

  17. Analyzing complex networks evolution through Information Theory quantifiers

    NASA Astrophysics Data System (ADS)

    Carpi, Laura C.; Rosso, Osvaldo A.; Saco, Patricia M.; Ravetti, Martín Gómez

    2011-01-01

    A methodology to analyze dynamical changes in complex networks based on Information Theory quantifiers is proposed. The square root of the Jensen-Shannon divergence, a measure of dissimilarity between two probability distributions, and the MPR Statistical Complexity are used to quantify states in the network evolution process. Three cases are analyzed, the Watts-Strogatz model, a gene network during the progression of Alzheimer's disease and a climate network for the Tropical Pacific region to study the El Niño/Southern Oscillation (ENSO) dynamic. We find that the proposed quantifiers are able not only to capture changes in the dynamics of the processes but also to quantify and compare states in their evolution.

  18. A Novel Estimator for the Rate of Information Transfer by Continuous Signals

    PubMed Central

    Takalo, Jouni; Ignatova, Irina; Weckström, Matti; Vähäsöyrinki, Mikko

    2011-01-01

    The information transfer rate provides an objective and rigorous way to quantify how much information is being transmitted through a communications channel whose input and output consist of time-varying signals. However, current estimators of information content in continuous signals are typically based on assumptions about the system's linearity and signal statistics, or they require prohibitive amounts of data. Here we present a novel information rate estimator without these limitations that is also optimized for computational efficiency. We validate the method with a simulated Gaussian information channel and demonstrate its performance with two example applications. Information transfer between the input and output signals of a nonlinear system is analyzed using a sensory receptor neuron as the model system. Then, a climate data set is analyzed to demonstrate that the method can be applied to a system based on two outputs generated by interrelated random processes. These analyses also demonstrate that the new method offers consistent performance in situations where classical methods fail. In addition to these examples, the method is applicable to a wide range of continuous time series commonly observed in the natural sciences, economics and engineering. PMID:21494562

  19. 28 CFR 22.24 - Information transfer agreement.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... STATISTICAL INFORMATION § 22.24 Information transfer agreement. Prior to the transfer of any identifiable... identifiable to a private person will be used only for research and statistical purposes. (b) Information...-know basis for research or statistical purposes, provided that such transfer is approved by the person...

  20. Quantifying ‘Causality’ in Complex Systems: Understanding Transfer Entropy

    PubMed Central

    Abdul Razak, Fatimah; Jensen, Henrik Jeldtoft

    2014-01-01

    ‘Causal’ direction is of great importance when dealing with complex systems. Often big volumes of data in the form of time series are available and it is important to develop methods that can inform about possible causal connections between the different observables. Here we investigate the ability of the Transfer Entropy measure to identify causal relations embedded in emergent coherent correlations. We do this by firstly applying Transfer Entropy to an amended Ising model. In addition we use a simple Random Transition model to test the reliability of Transfer Entropy as a measure of ‘causal’ direction in the presence of stochastic fluctuations. In particular we systematically study the effect of the finite size of data sets. PMID:24955766

  1. Information transfer in community structured multiplex networks

    NASA Astrophysics Data System (ADS)

    Solé Ribalta, Albert; Granell, Clara; Gómez, Sergio; Arenas, Alex

    2015-08-01

    The study of complex networks that account for different types of interactions has become a subject of interest in the last few years, specially because its representational power in the description of users interactions in diverse online social platforms (Facebook, Twitter, Instagram, etc.). The mathematical description of these interacting networks has been coined under the name of multilayer networks, where each layer accounts for a type of interaction. It has been shown that diffusive processes on top of these networks present a phenomenology that cannot be explained by the naive superposition of single layer diffusive phenomena but require the whole structure of interconnected layers. Nevertheless, the description of diffusive phenomena on multilayer networks has obviated the fact that social networks have strong mesoscopic structure represented by different communities of individuals driven by common interests, or any other social aspect. In this work, we study the transfer of information in multilayer networks with community structure. The final goal is to understand and quantify, if the existence of well-defined community structure at the level of individual layers, together with the multilayer structure of the whole network, enhances or deteriorates the diffusion of packets of information.

  2. Brain control and information transfer.

    PubMed

    Tehovnik, Edward J; Chen, Lewis L

    2015-12-01

    In this review, we examine the importance of having a body as essential for the brain to transfer information about the outside world to generate appropriate motor responses. We discuss the context-dependent conditioning of the motor control neural circuits and its dependence on the completion of feedback loops, which is in close agreement with the insights of Hebb and colleagues, who have stressed that for learning to occur the body must be intact and able to interact with the outside world. Finally, we apply information theory to data from published studies to evaluate the robustness of the neuronal signals obtained by bypassing the body (as used for brain-machine interfaces) versus via the body to move in the world. We show that recording from a group of neurons that bypasses the body exhibits a vastly degraded level of transfer of information as compared to that of an entire brain using the body to engage in the normal execution of behaviour. We conclude that body sensations provide more than just feedback for movements; they sustain the necessary transfer of information as animals explore their environment, thereby creating associations through learning. This work has implications for the development of brain-machine interfaces used to move external devices.

  3. Information on Quantifiers and Argument Structure in English Learner's Dictionaries.

    ERIC Educational Resources Information Center

    Lee, Thomas Hun-tak

    1993-01-01

    Lexicographers have been arguing for the inclusion of abstract and complex grammatical information in dictionaries. This paper examines the extent to which information about quantifiers and the argument structure of verbs is encoded in English learner's dictionaries. The Oxford Advanced Learner's Dictionary (1989), the Longman Dictionary of…

  4. Quantifying uncertainty in climate change science through empirical information theory.

    PubMed

    Majda, Andrew J; Gershgorin, Boris

    2010-08-24

    Quantifying the uncertainty for the present climate and the predictions of climate change in the suite of imperfect Atmosphere Ocean Science (AOS) computer models is a central issue in climate change science. Here, a systematic approach to these issues with firm mathematical underpinning is developed through empirical information theory. An information metric to quantify AOS model errors in the climate is proposed here which incorporates both coarse-grained mean model errors as well as covariance ratios in a transformation invariant fashion. The subtle behavior of model errors with this information metric is quantified in an instructive statistically exactly solvable test model with direct relevance to climate change science including the prototype behavior of tracer gases such as CO(2). Formulas for identifying the most sensitive climate change directions using statistics of the present climate or an AOS model approximation are developed here; these formulas just involve finding the eigenvector associated with the largest eigenvalue of a quadratic form computed through suitable unperturbed climate statistics. These climate change concepts are illustrated on a statistically exactly solvable one-dimensional stochastic model with relevance for low frequency variability of the atmosphere. Viable algorithms for implementation of these concepts are discussed throughout the paper.

  5. Information to Change the World--Fulfilling the Information Needs of Technology Transfer.

    ERIC Educational Resources Information Center

    Duberman, Josh; Zeller, Martin

    1996-01-01

    Provides an introduction to fulfilling the information needs of technology transfer. Highlights include a definition of technology transfer; government and university involvement; industry's role; publishers; an annotated list of information sources and contacts; technology assessment, including patent searching, competitive intelligence, and…

  6. Measuring Information-Transfer Delays

    PubMed Central

    Wibral, Michael; Pampu, Nicolae; Priesemann, Viola; Siebenhühner, Felix; Seiwert, Hannes; Lindner, Michael; Lizier, Joseph T.; Vicente, Raul

    2013-01-01

    In complex networks such as gene networks, traffic systems or brain circuits it is important to understand how long it takes for the different parts of the network to effectively influence one another. In the brain, for example, axonal delays between brain areas can amount to several tens of milliseconds, adding an intrinsic component to any timing-based processing of information. Inferring neural interaction delays is thus needed to interpret the information transfer revealed by any analysis of directed interactions across brain structures. However, a robust estimation of interaction delays from neural activity faces several challenges if modeling assumptions on interaction mechanisms are wrong or cannot be made. Here, we propose a robust estimator for neuronal interaction delays rooted in an information-theoretic framework, which allows a model-free exploration of interactions. In particular, we extend transfer entropy to account for delayed source-target interactions, while crucially retaining the conditioning on the embedded target state at the immediately previous time step. We prove that this particular extension is indeed guaranteed to identify interaction delays between two coupled systems and is the only relevant option in keeping with Wiener’s principle of causality. We demonstrate the performance of our approach in detecting interaction delays on finite data by numerical simulations of stochastic and deterministic processes, as well as on local field potential recordings. We also show the ability of the extended transfer entropy to detect the presence of multiple delays, as well as feedback loops. While evaluated on neuroscience data, we expect the estimator to be useful in other fields dealing with network dynamics. PMID:23468850

  7. Quantifying Information Gain from Dynamic Downscaling Experiments

    NASA Astrophysics Data System (ADS)

    Tian, Y.; Peters-Lidard, C. D.

    2015-12-01

    Dynamic climate downscaling experiments are designed to produce information at higher spatial and temporal resolutions. Such additional information is generated from the low-resolution initial and boundary conditions via the predictive power of the physical laws. However, errors and uncertainties in the initial and boundary conditions can be propagated and even amplified to the downscaled simulations. Additionally, the limit of predictability in nonlinear dynamical systems will also damper the information gain, even if the initial and boundary conditions were error-free. Thus it is critical to quantitatively define and measure the amount of information increase from dynamic downscaling experiments, to better understand and appreciate their potentials and limitations. We present a scheme to objectively measure the information gain from such experiments. The scheme is based on information theory, and we argue that if a downscaling experiment is to exhibit value, it has to produce more information than what can be simply inferred from information sources already available. These information sources include the initial and boundary conditions, the coarse resolution model in which the higher-resolution models are embedded, and the same set of physical laws. These existing information sources define an "information threshold" as a function of the spatial and temporal resolution, and this threshold serves as a benchmark to quantify the information gain from the downscaling experiments, or any other approaches. For a downscaling experiment to shown any value, the information has to be above this threshold. A recent NASA-supported downscaling experiment is used as an example to illustrate the application of this scheme.

  8. Information Transfer in 1990.

    ERIC Educational Resources Information Center

    Hough, Roger W.

    Results of a recent study of potential demand for electronic information transfer services in 1970-1990 are presented. Projections are made for new services such as electronic mail, remote library browsing, checkless society transactions, video telephone and others, as well as conventional services such as telephone, telegraph and network program…

  9. Part mutual information for quantifying direct associations in networks.

    PubMed

    Zhao, Juan; Zhou, Yiwei; Zhang, Xiujun; Chen, Luonan

    2016-05-03

    Quantitatively identifying direct dependencies between variables is an important task in data analysis, in particular for reconstructing various types of networks and causal relations in science and engineering. One of the most widely used criteria is partial correlation, but it can only measure linearly direct association and miss nonlinear associations. However, based on conditional independence, conditional mutual information (CMI) is able to quantify nonlinearly direct relationships among variables from the observed data, superior to linear measures, but suffers from a serious problem of underestimation, in particular for those variables with tight associations in a network, which severely limits its applications. In this work, we propose a new concept, "partial independence," with a new measure, "part mutual information" (PMI), which not only can overcome the problem of CMI but also retains the quantification properties of both mutual information (MI) and CMI. Specifically, we first defined PMI to measure nonlinearly direct dependencies between variables and then derived its relations with MI and CMI. Finally, we used a number of simulated data as benchmark examples to numerically demonstrate PMI features and further real gene expression data from Escherichia coli and yeast to reconstruct gene regulatory networks, which all validated the advantages of PMI for accurately quantifying nonlinearly direct associations in networks.

  10. 28 CFR 22.26 - Requests for transfer of information.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 28 Judicial Administration 1 2011-07-01 2011-07-01 false Requests for transfer of information. 22.26 Section 22.26 Judicial Administration DEPARTMENT OF JUSTICE CONFIDENTIALITY OF IDENTIFIABLE RESEARCH AND STATISTICAL INFORMATION § 22.26 Requests for transfer of information. (a) Requests for...

  11. 28 CFR 22.26 - Requests for transfer of information.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Requests for transfer of information. 22.26 Section 22.26 Judicial Administration DEPARTMENT OF JUSTICE CONFIDENTIALITY OF IDENTIFIABLE RESEARCH AND STATISTICAL INFORMATION § 22.26 Requests for transfer of information. (a) Requests for...

  12. Information transfer in auditoria and room-acoustical quality.

    PubMed

    Summers, Jason E

    2013-04-01

    It is hypothesized that room-acoustical quality correlates with the information-transfer rate. Auditoria are considered as multiple-input multiple-output communication channels and a theory of information-transfer is outlined that accounts for time-variant multipath, spatial hearing, and distributed directional sources. Source diversity and spatial hearing are shown to be the mechanisms through which multipath increases the information-transfer rate by overcoming finite spatial resolution. In addition to predictions that are confirmed by recent and historical findings, the theory provides explanations for the influence of factors such as musical repertoire and ensemble size on subjective preference and the influence of multisource, multichannel auralization on perceived realism.

  13. New scaling relation for information transfer in biological networks

    PubMed Central

    Kim, Hyunju; Davies, Paul; Walker, Sara Imari

    2015-01-01

    We quantify characteristics of the informational architecture of two representative biological networks: the Boolean network model for the cell-cycle regulatory network of the fission yeast Schizosaccharomyces pombe (Davidich et al. 2008 PLoS ONE 3, e1672 (doi:10.1371/journal.pone.0001672)) and that of the budding yeast Saccharomyces cerevisiae (Li et al. 2004 Proc. Natl Acad. Sci. USA 101, 4781–4786 (doi:10.1073/pnas.0305937101)). We compare our results for these biological networks with the same analysis performed on ensembles of two different types of random networks: Erdös–Rényi and scale-free. We show that both biological networks share features in common that are not shared by either random network ensemble. In particular, the biological networks in our study process more information than the random networks on average. Both biological networks also exhibit a scaling relation in information transferred between nodes that distinguishes them from random, where the biological networks stand out as distinct even when compared with random networks that share important topological properties, such as degree distribution, with the biological network. We show that the most biologically distinct regime of this scaling relation is associated with a subset of control nodes that regulate the dynamics and function of each respective biological network. Information processing in biological networks is therefore interpreted as an emergent property of topology (causal structure) and dynamics (function). Our results demonstrate quantitatively how the informational architecture of biologically evolved networks can distinguish them from other classes of network architecture that do not share the same informational properties. PMID:26701883

  14. 76 FR 14370 - Information Collection; Transfer of Farm Records Between Counties

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-16

    ... DEPARTMENT OF AGRICULTURE Farm Service Agency Information Collection; Transfer of Farm Records... collection associated with transferring of farm records from one administrative county office to another..., Agricultural Program Specialist, (202) 720-5422. SUPPLEMENTARY INFORMATION: Title: Transfer of Farm Records...

  15. Air-ground information transfer in the National Airspace System

    NASA Technical Reports Server (NTRS)

    Lee, Alfred T.; Lozito, Sandra

    1989-01-01

    This paper reviews NASA's Aviation Safety Reporting System incident data for a two-year period in order to identify the frequency of air-ground information transfer errors and the factors associated with their occurrence. Of the more than 14,000 primary reports received during the 1985 and 1986 reporting period, one out of four reports concerned problems of information transfer between aircraft and ATC. Approximately half of these errors were associated directly or indirectly with aircraft deviations from assigned heading or altitude. The majority of incidents cited some human-system problem such as workload, cockpit distractions, etc., as the primary contributing factor. Improvements in air-ground information transfer using existing and future (e.g., data link) technology are proposed centering on the development and application of user-centered information management principles.

  16. Measuring information transfer in a soft robotic arm.

    PubMed

    Nakajima, K; Schmidt, N; Pfeifer, R

    2015-05-13

    Soft robots can exhibit diverse behaviors with simple types of actuation by partially outsourcing control to the morphological and material properties of their soft bodies, which is made possible by the tight coupling between control, body, and environment. In this paper, we present a method that will quantitatively characterize these diverse spatiotemporal dynamics of a soft body based on the information-theoretic approach. In particular, soft bodies have the ability to propagate the effect of actuation through the entire body, with a certain time delay, due to their elasticity. Our goal is to capture this delayed interaction in a quantitative manner based on a measure called momentary information transfer. We extend this measure to soft robotic applications and demonstrate its power using a physical soft robotic platform inspired by the octopus. Our approach is illustrated in two ways. First, we statistically characterize the delayed actuation propagation through the body as a strength of information transfer. Second, we capture this information propagation directly as local information dynamics. As a result, we show that our approach can successfully characterize the spatiotemporal dynamics of the soft robotic platform, explicitly visualizing how information transfers through the entire body with delays. Further extension scenarios of our approach are discussed for soft robotic applications in general.

  17. Feedback Specificity, Information Processing, and Transfer of Training

    ERIC Educational Resources Information Center

    Goodman, Jodi S.; Wood, Robert E.; Chen, Zheng

    2011-01-01

    This study examines the effects of feedback specificity on transfer of training and the mechanisms through which feedback can enhance or inhibit transfer. We used concurrent verbal protocol methodology to elicit and operationalize the explicit information processing activities used by 48 trainees performing the Furniture Factory computer…

  18. Serotonergic psychedelics temporarily modify information transfer in humans.

    PubMed

    Alonso, Joan Francesc; Romero, Sergio; Mañanas, Miquel Àngel; Riba, Jordi

    2015-03-28

    Psychedelics induce intense modifications in the sensorium, the sense of "self," and the experience of reality. Despite advances in our understanding of the molecular and cellular level mechanisms of these drugs, knowledge of their actions on global brain dynamics is still incomplete. Recent imaging studies have found changes in functional coupling between frontal and parietal brain structures, suggesting a modification in information flow between brain regions during acute effects. Here we assessed the psychedelic-induced changes in directionality of information flow during the acute effects of a psychedelic in humans. We measured modifications in connectivity of brain oscillations using transfer entropy, a nonlinear measure of directed functional connectivity based on information theory. Ten healthy male volunteers with prior experience with psychedelics participated in 2 experimental sessions. They received a placebo or a dose of ayahuasca, a psychedelic preparation containing the serotonergic 5-HT2A agonist N,N-dimethyltryptamine. The analysis showed significant changes in the coupling of brain oscillations between anterior and posterior recording sites. Transfer entropy analysis showed that frontal sources decreased their influence over central, parietal, and occipital sites. Conversely, sources in posterior locations increased their influence over signals measured at anterior locations. Exploratory correlations found that anterior-to-posterior transfer entropy decreases were correlated with the intensity of subjective effects, while the imbalance between anterior-to-posterior and posterior-to-anterior transfer entropy correlated with the degree of incapacitation experienced. These results suggest that psychedelics induce a temporary disruption of neural hierarchies by reducing top-down control and increasing bottom-up information transfer in the human brain. © The Author 2015. Published by Oxford University Press on behalf of CINP.

  19. Serotonergic Psychedelics Temporarily Modify Information Transfer in Humans

    PubMed Central

    Alonso, Joan Francesc; Romero, Sergio; Mañanas, Miquel Àngel

    2015-01-01

    Background: Psychedelics induce intense modifications in the sensorium, the sense of “self,” and the experience of reality. Despite advances in our understanding of the molecular and cellular level mechanisms of these drugs, knowledge of their actions on global brain dynamics is still incomplete. Recent imaging studies have found changes in functional coupling between frontal and parietal brain structures, suggesting a modification in information flow between brain regions during acute effects. Methods: Here we assessed the psychedelic-induced changes in directionality of information flow during the acute effects of a psychedelic in humans. We measured modifications in connectivity of brain oscillations using transfer entropy, a nonlinear measure of directed functional connectivity based on information theory. Ten healthy male volunteers with prior experience with psychedelics participated in 2 experimental sessions. They received a placebo or a dose of ayahuasca, a psychedelic preparation containing the serotonergic 5-HT2A agonist N,N-dimethyltryptamine. Results: The analysis showed significant changes in the coupling of brain oscillations between anterior and posterior recording sites. Transfer entropy analysis showed that frontal sources decreased their influence over central, parietal, and occipital sites. Conversely, sources in posterior locations increased their influence over signals measured at anterior locations. Exploratory correlations found that anterior-to-posterior transfer entropy decreases were correlated with the intensity of subjective effects, while the imbalance between anterior-to-posterior and posterior-to-anterior transfer entropy correlated with the degree of incapacitation experienced. Conclusions: These results suggest that psychedelics induce a temporary disruption of neural hierarchies by reducing top-down control and increasing bottom-up information transfer in the human brain. PMID:25820842

  20. Quantifying Complexity in Quantum Phase Transitions via Mutual Information Complex Networks

    NASA Astrophysics Data System (ADS)

    Valdez, Marc Andrew; Jaschke, Daniel; Vargas, David L.; Carr, Lincoln D.

    2017-12-01

    We quantify the emergent complexity of quantum states near quantum critical points on regular 1D lattices, via complex network measures based on quantum mutual information as the adjacency matrix, in direct analogy to quantifying the complexity of electroencephalogram or functional magnetic resonance imaging measurements of the brain. Using matrix product state methods, we show that network density, clustering, disparity, and Pearson's correlation obtain the critical point for both quantum Ising and Bose-Hubbard models to a high degree of accuracy in finite-size scaling for three classes of quantum phase transitions, Z2, mean field superfluid to Mott insulator, and a Berzinskii-Kosterlitz-Thouless crossover.

  1. Information Dissemination and Technology Transfer in Telecommunications.

    ERIC Educational Resources Information Center

    Roderer, Nancy K.; King, Donald W.

    Using a model of scientific and technical information transfer as a framework, this document focuses on four types of activities: the generation or authorship of telecommunications information and its publication, distribution, and use. Different forms of publication are considered in each functional area, though primary emphasis is on the…

  2. Year 7 Students, Information Literacy, and Transfer: A Grounded Theory

    ERIC Educational Resources Information Center

    Herring, James E.

    2011-01-01

    This study examined the views of year 7 students, teacher librarians, and teachers in three state secondary schools in rural New South Wales, Australia, on information literacy and transfer. The aims of the study included the development of a grounded theory in relation to information literacy and transfer in these schools. The study's perspective…

  3. Noise enhances information transfer in hierarchical networks.

    PubMed

    Czaplicka, Agnieszka; Holyst, Janusz A; Sloot, Peter M A

    2013-01-01

    We study the influence of noise on information transmission in the form of packages shipped between nodes of hierarchical networks. Numerical simulations are performed for artificial tree networks, scale-free Ravasz-Barabási networks as well for a real network formed by email addresses of former Enron employees. Two types of noise are considered. One is related to packet dynamics and is responsible for a random part of packets paths. The second one originates from random changes in initial network topology. We find that the information transfer can be enhanced by the noise. The system possesses optimal performance when both kinds of noise are tuned to specific values, this corresponds to the Stochastic Resonance phenomenon. There is a non-trivial synergy present for both noisy components. We found also that hierarchical networks built of nodes of various degrees are more efficient in information transfer than trees with a fixed branching factor.

  4. Noise enhances information transfer in hierarchical networks

    PubMed Central

    Czaplicka, Agnieszka; Holyst, Janusz A.; Sloot, Peter M. A.

    2013-01-01

    We study the influence of noise on information transmission in the form of packages shipped between nodes of hierarchical networks. Numerical simulations are performed for artificial tree networks, scale-free Ravasz-Barabási networks as well for a real network formed by email addresses of former Enron employees. Two types of noise are considered. One is related to packet dynamics and is responsible for a random part of packets paths. The second one originates from random changes in initial network topology. We find that the information transfer can be enhanced by the noise. The system possesses optimal performance when both kinds of noise are tuned to specific values, this corresponds to the Stochastic Resonance phenomenon. There is a non-trivial synergy present for both noisy components. We found also that hierarchical networks built of nodes of various degrees are more efficient in information transfer than trees with a fixed branching factor. PMID:23390574

  5. International Co-operation and Trends in Social Science Information Transfer.

    ERIC Educational Resources Information Center

    Rozsa, Gyorgy; Foldi, Tamas

    1980-01-01

    Identifies the role and mechanism of information transfer in the social sciences, and surveys selected, significant institutions and organizations (mostly international), which promote such transfer. (RAA)

  6. An application protocol for CAD to CAD transfer of electronic information

    NASA Technical Reports Server (NTRS)

    Azu, Charles C., Jr.

    1993-01-01

    The exchange of Computer Aided Design (CAD) information between dissimilar CAD systems is a problem. This is especially true for transferring electronics CAD information such as multi-chip module (MCM), hybrid microcircuit assembly (HMA), and printed circuit board (PCB) designs. Currently, there exists several neutral data formats for transferring electronics CAD information. These include IGES, EDIF, and DXF formats. All these formats have limitations for use in exchanging electronic data. In an attempt to overcome these limitations, the Navy's MicroCIM program implemented a project to transfer hybrid microcircuit design information between dissimilar CAD systems. The IGES (Initial Graphics Exchange Specification) format is used since it is well established within the CAD industry. The goal of the project is to have a complete transfer of microelectronic CAD information, using IGES, without any data loss. An Application Protocol (AP) is being developed to specify how hybrid microcircuit CAD information will be represented by IGES entity constructs. The AP defines which IGES data items are appropriate for describing HMA geometry, connectivity, and processing as well as HMA material characteristics.

  7. Transfer Entropy and Transient Limits of Computation

    PubMed Central

    Prokopenko, Mikhail; Lizier, Joseph T.

    2014-01-01

    Transfer entropy is a recently introduced information-theoretic measure quantifying directed statistical coherence between spatiotemporal processes, and is widely used in diverse fields ranging from finance to neuroscience. However, its relationships to fundamental limits of computation, such as Landauer's limit, remain unknown. Here we show that in order to increase transfer entropy (predictability) by one bit, heat flow must match or exceed Landauer's limit. Importantly, we generalise Landauer's limit to bi-directional information dynamics for non-equilibrium processes, revealing that the limit applies to prediction, in addition to retrodiction (information erasure). Furthermore, the results are related to negentropy, and to Bremermann's limit and the Bekenstein bound, producing, perhaps surprisingly, lower bounds on the computational deceleration and information loss incurred during an increase in predictability about the process. The identified relationships set new computational limits in terms of fundamental physical quantities, and establish transfer entropy as a central measure connecting information theory, thermodynamics and theory of computation. PMID:24953547

  8. A case report in health information exchange for inter-organizational patient transfers.

    PubMed

    Richardson, J E; Malhotra, S; Kaushal, R

    2014-01-01

    To provide a case report of barriers and promoters to implementing a health information exchange (HIE) tool that supports patient transfers between hospitals and skilled nursing facilities. A multi-disciplinary team conducted semi-structured telephone and in-person interviews in a purposive sample of HIE organizational informants and providers in New York City who implemented HIE to share patient transfer information. The researchers conducted grounded theory analysis to identify themes of barriers and promoters and took steps to improve the trustworthiness of the results including vetting from a knowledgeable study participant. Between May and October 2011, researchers recruited 18 participants: informaticians, healthcare administrators, software engineers, and providers from a skilled nursing facility. Subjects perceived the HIE tool's development a success in that it brought together stakeholders who had traditionally not partnered for informatics work, and that they could successfully share patient transfer information between a hospital and a skilled nursing facility. Perceived barriers included lack of hospital stakeholder buy-in and misalignment with clinical workflows that inhibited use of HIE-based patient transfer data. Participants described barriers and promoters in themes related to organizational, technical, and user-oriented issues. The investigation revealed that stakeholders could develop and implement health information technology that technically enables clinicians in both hospitals and skilled nursing facilities to exchange real-time information in support of patient transfers. User level barriers, particularly in the emergency department, should give pause to developers and implementers who plan to use HIE in support of patient transfers. Participants' experiences demonstrate how stakeholders may succeed in developing and piloting an electronic transfer form that relies on HIE to aggregate, communicate, and display relevant patient transfer

  9. Information criteria for quantifying loss of reversibility in parallelized KMC

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gourgoulias, Konstantinos, E-mail: gourgoul@math.umass.edu; Katsoulakis, Markos A., E-mail: markos@math.umass.edu; Rey-Bellet, Luc, E-mail: luc@math.umass.edu

    Parallel Kinetic Monte Carlo (KMC) is a potent tool to simulate stochastic particle systems efficiently. However, despite literature on quantifying domain decomposition errors of the particle system for this class of algorithms in the short and in the long time regime, no study yet explores and quantifies the loss of time-reversibility in Parallel KMC. Inspired by concepts from non-equilibrium statistical mechanics, we propose the entropy production per unit time, or entropy production rate, given in terms of an observable and a corresponding estimator, as a metric that quantifies the loss of reversibility. Typically, this is a quantity that cannot bemore » computed explicitly for Parallel KMC, which is why we develop a posteriori estimators that have good scaling properties with respect to the size of the system. Through these estimators, we can connect the different parameters of the scheme, such as the communication time step of the parallelization, the choice of the domain decomposition, and the computational schedule, with its performance in controlling the loss of reversibility. From this point of view, the entropy production rate can be seen both as an information criterion to compare the reversibility of different parallel schemes and as a tool to diagnose reversibility issues with a particular scheme. As a demonstration, we use Sandia Lab's SPPARKS software to compare different parallelization schemes and different domain (lattice) decompositions.« less

  10. Information criteria for quantifying loss of reversibility in parallelized KMC

    NASA Astrophysics Data System (ADS)

    Gourgoulias, Konstantinos; Katsoulakis, Markos A.; Rey-Bellet, Luc

    2017-01-01

    Parallel Kinetic Monte Carlo (KMC) is a potent tool to simulate stochastic particle systems efficiently. However, despite literature on quantifying domain decomposition errors of the particle system for this class of algorithms in the short and in the long time regime, no study yet explores and quantifies the loss of time-reversibility in Parallel KMC. Inspired by concepts from non-equilibrium statistical mechanics, we propose the entropy production per unit time, or entropy production rate, given in terms of an observable and a corresponding estimator, as a metric that quantifies the loss of reversibility. Typically, this is a quantity that cannot be computed explicitly for Parallel KMC, which is why we develop a posteriori estimators that have good scaling properties with respect to the size of the system. Through these estimators, we can connect the different parameters of the scheme, such as the communication time step of the parallelization, the choice of the domain decomposition, and the computational schedule, with its performance in controlling the loss of reversibility. From this point of view, the entropy production rate can be seen both as an information criterion to compare the reversibility of different parallel schemes and as a tool to diagnose reversibility issues with a particular scheme. As a demonstration, we use Sandia Lab's SPPARKS software to compare different parallelization schemes and different domain (lattice) decompositions.

  11. Forest Resource Information System. Phase 3: System transfer report

    NASA Technical Reports Server (NTRS)

    Mroczynski, R. P. (Principal Investigator)

    1981-01-01

    Transfer of the forest reserve information system (FRIS) from the Laboratory for Applications of Remote Sensing to St. Regis Paper Company is described. Modifications required for the transfer of the LARYS image processing software are discussed. The reformatting, geometric correction, image registration, and documentation performed for preprocessing transfer are described. Data turnaround was improved and geometrically corrected and ground-registered CCT LANDSAT 3 data provided to the user. The technology transfer activities are summarized. An application test performed in order to assess a Florida land acquisition is described. A benefit/cost analysis of FRIS is presented.

  12. Measuring transferring similarity via local information

    NASA Astrophysics Data System (ADS)

    Yin, Likang; Deng, Yong

    2018-05-01

    Recommender systems have developed along with the web science, and how to measure the similarity between users is crucial for processing collaborative filtering recommendation. Many efficient models have been proposed (i.g., the Pearson coefficient) to measure the direct correlation. However, the direct correlation measures are greatly affected by the sparsity of dataset. In other words, the direct correlation measures would present an inauthentic similarity if two users have a very few commonly selected objects. Transferring similarity overcomes this drawback by considering their common neighbors (i.e., the intermediates). Yet, the transferring similarity also has its drawback since it can only provide the interval of similarity. To break the limitations, we propose the Belief Transferring Similarity (BTS) model. The contributions of BTS model are: (1) BTS model addresses the issue of the sparsity of dataset by considering the high-order similarity. (2) BTS model transforms uncertain interval to a certain state based on fuzzy systems theory. (3) BTS model is able to combine the transferring similarity of different intermediates using information fusion method. Finally, we compare BTS models with nine different link prediction methods in nine different networks, and we also illustrate the convergence property and efficiency of the BTS model.

  13. Information Systems and Networks for Technology Transfer. Final Report.

    ERIC Educational Resources Information Center

    Page, John; Szentivanyi, Tibor

    Results of a survey of the information resources available in industrialized countries which might be used in a United Nations technology transfer program for developing countries are presented. Information systems and networks, organized information collections of a scientific and technical character, and the machinery used to disseminate this…

  14. Entropy-Based Analysis and Bioinformatics-Inspired Integration of Global Economic Information Transfer

    PubMed Central

    An, Sungbae; Kwon, Young-Kyun; Yoon, Sungroh

    2013-01-01

    The assessment of information transfer in the global economic network helps to understand the current environment and the outlook of an economy. Most approaches on global networks extract information transfer based mainly on a single variable. This paper establishes an entirely new bioinformatics-inspired approach to integrating information transfer derived from multiple variables and develops an international economic network accordingly. In the proposed methodology, we first construct the transfer entropies (TEs) between various intra- and inter-country pairs of economic time series variables, test their significances, and then use a weighted sum approach to aggregate information captured in each TE. Through a simulation study, the new method is shown to deliver better information integration compared to existing integration methods in that it can be applied even when intra-country variables are correlated. Empirical investigation with the real world data reveals that Western countries are more influential in the global economic network and that Japan has become less influential following the Asian currency crisis. PMID:23300959

  15. Entropy-based analysis and bioinformatics-inspired integration of global economic information transfer.

    PubMed

    Kim, Jinkyu; Kim, Gunn; An, Sungbae; Kwon, Young-Kyun; Yoon, Sungroh

    2013-01-01

    The assessment of information transfer in the global economic network helps to understand the current environment and the outlook of an economy. Most approaches on global networks extract information transfer based mainly on a single variable. This paper establishes an entirely new bioinformatics-inspired approach to integrating information transfer derived from multiple variables and develops an international economic network accordingly. In the proposed methodology, we first construct the transfer entropies (TEs) between various intra- and inter-country pairs of economic time series variables, test their significances, and then use a weighted sum approach to aggregate information captured in each TE. Through a simulation study, the new method is shown to deliver better information integration compared to existing integration methods in that it can be applied even when intra-country variables are correlated. Empirical investigation with the real world data reveals that Western countries are more influential in the global economic network and that Japan has become less influential following the Asian currency crisis.

  16. Implementing AORN recommended practices for transfer of patient care information.

    PubMed

    Seifert, Patricia C

    2012-11-01

    The Joint Commission estimates that 80% of serious medical errors are associated with miscommunication during patient transfers. Patient transfers may occur between a wide array of settings: between physicians' offices or preoperative areas and traditional ORs or ambulatory settings, between emergency departments or interventional suites and the OR, and between other areas where the exchange of patient information occurs. AORN's "Recommended practices for transfer of patient care information" serves as a guide for establishing achievable practices that promote a safe level of care during perioperative patient transfers. Strategies for the successful implementation of the recommended practices include promoting teamwork, including with the patient and the patient's family members; developing effective communication skills; documenting processes; creating and adhering to policies and procedures; and establishing quality management programs. Copyright © 2012 AORN, Inc. Published by Elsevier Inc. All rights reserved.

  17. Information Transfer Capacity of Articulators in American Sign Language.

    PubMed

    Malaia, Evie; Borneman, Joshua D; Wilbur, Ronnie B

    2018-03-01

    The ability to convey information is a fundamental property of communicative signals. For sign languages, which are overtly produced with multiple, completely visible articulators, the question arises as to how the various channels co-ordinate and interact with each other. We analyze motion capture data of American Sign Language (ASL) narratives, and show that the capacity of information throughput, mathematically defined, is highest on the dominant hand (DH). We further demonstrate that information transfer capacity is also significant for the non-dominant hand (NDH), and the head channel too, as compared to control channels (ankles). We discuss both redundancy and independence in articulator motion in sign language, and argue that the NDH and the head articulators contribute to the overall information transfer capacity, indicating that they are neither completely redundant to, nor completely independent of, the DH.

  18. Quantifying control effort of biological and technical movements: an information-entropy-based approach.

    PubMed

    Haeufle, D F B; Günther, M; Wunner, G; Schmitt, S

    2014-01-01

    In biomechanics and biorobotics, muscles are often associated with reduced movement control effort and simplified control compared to technical actuators. This is based on evidence that the nonlinear muscle properties positively influence movement control. It is, however, open how to quantify the simplicity aspect of control effort and compare it between systems. Physical measures, such as energy consumption, stability, or jerk, have already been applied to compare biological and technical systems. Here a physical measure of control effort based on information entropy is presented. The idea is that control is simpler if a specific movement is generated with less processed sensor information, depending on the control scheme and the physical properties of the systems being compared. By calculating the Shannon information entropy of all sensor signals required for control, an information cost function can be formulated allowing the comparison of models of biological and technical control systems. Exemplarily applied to (bio-)mechanical models of hopping, the method reveals that the required information for generating hopping with a muscle driven by a simple reflex control scheme is only I=32 bits versus I=660 bits with a DC motor and a proportional differential controller. This approach to quantifying control effort captures the simplicity of a control scheme and can be used to compare completely different actuators and control approaches.

  19. A Survey on Simultaneous Wireless Information and Power Transfer

    NASA Astrophysics Data System (ADS)

    Perera, T. D. P.; Jayakody, D. N. K.; De, S.; Ivanov, M. A.

    2017-01-01

    This paper presents a comprehensive study related to simultaneous wireless information and power transfer (SWIPT) in different types of wireless communication setups. Harvesting energy using SWIPT is an appealing solution in the context of extending battery life of wireless devices for a fully sustainable communication system. Strong signal power increases power transfer, but also causes more interference in information transfer, causing realization of the SWIPT challenging problem. This article provides an overview of technical evolution of SWIPT. A survey and qualitative comparison of the existing SWIPT schemes is provided to demonstrate their limitations in the current and 5G networks. Open challenges are emphasized and guidelines are provided to adapt the existing schemes in order to overcome these limitations and make them fit for integrating with the modern and emerging next generation communication networks, such as 5G systems.

  20. 77 FR 34127 - Financial Management Service; Proposed Collection of Information: Electronic Transfer Account...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-08

    ... Information: Electronic Transfer Account (ETA) Financial Agency Agreement AGENCY: Financial Management Service... of information described below: Title: Electronic Transfer Account (ETA) Financial Agency Agreement... public and other Federal agencies to take this opportunity to comment on a continuing information...

  1. Genetic information transfer promotes cooperation in bacteria

    PubMed Central

    Dimitriu, Tatiana; Lotton, Chantal; Bénard-Capelle, Julien; Misevic, Dusan; Brown, Sam P.; Lindner, Ariel B.; Taddei, François

    2014-01-01

    Many bacterial species are social, producing costly secreted “public good” molecules that enhance the growth of neighboring cells. The genes coding for these cooperative traits are often propagated via mobile genetic elements and can be virulence factors from a biomedical perspective. Here, we present an experimental framework that links genetic information exchange and the selection of cooperative traits. Using simulations and experiments based on a synthetic bacterial system to control public good secretion and plasmid conjugation, we demonstrate that horizontal gene transfer can favor cooperation. In a well-mixed environment, horizontal transfer brings a direct infectious advantage to any gene, regardless of its cooperation properties. However, in a structured population transfer selects specifically for cooperation by increasing the assortment among cooperative alleles. Conjugation allows cooperative alleles to overcome rarity thresholds and invade bacterial populations structured purely by stochastic dilution effects. Our results provide an explanation for the prevalence of cooperative genes on mobile elements, and suggest a previously unidentified benefit of horizontal gene transfer for bacteria. PMID:25024219

  2. A Case Study of Information Transfer by Social Change Organizations.

    ERIC Educational Resources Information Center

    Macfarlane, Ronald G.

    1984-01-01

    Examines the information needs of social change organizations using the peace and disarmament movement in Toronto as a case study. The process of information transfer, sources and places to obtain information, information distribution, and how libraries can better meet information needs of community organizations are discussed. Eight references…

  3. Mapping and quantifying sediment transfer between the front of rapidly moving rock glaciers and torrential gullies

    NASA Astrophysics Data System (ADS)

    Kummert, Mario; Delaloye, Reynald

    2018-05-01

    The sedimentary connection which may occur between the front of active rock glaciers and torrential channels is not well understood, despite its potential impact on the torrential activity characterizing the concerned catchments. In this study, DEMs of difference (DoDs) covering various time intervals between 2013 and 2016 were obtained from LiDAR-derived multitemporal DEMs for three rapidly moving rock glaciers located in the western Swiss Alps. The DoDs were used to map and quantify sediment transfer activity between the front of these rock glaciers and the corresponding underlying torrential gullies. Sediment transfer rates ranging between 1500 m3/y and 7800 m3/y have been calculated, depending on the sites. Sediment eroded from the fronts generally accumulated in the upper sectors of the torrential gullies where they were occasionally mobilized within small to medium sized debris flow events. A clear relation between the motion rates of the rock glaciers and the sediment transfer rates calculated at their fronts could be highlighted. Along with the size of the frontal areas, rock glacier creep rates influence thus directly sediment availability in the headwaters of the studied torrents. The frequency-magnitude of debris flow events varied between sites and was mainly related to the concordance of local factors such as topography, water availability, sediment availability or sediment type.

  4. Information transfer across intra/inter-structure of CDS and stock markets

    NASA Astrophysics Data System (ADS)

    Lim, Kyuseong; Kim, Sehyun; Kim, Soo Yong

    2017-11-01

    We investigate the information flow between industrial sectors in credit default swap and stock markets in the United States based on transfer entropy. Both markets have been studied with respect to dynamics and relations. Our approach considers the intra-structure of each financial market as well as the inter-structure between two markets through a moving window in order to scan a period from 2005 to 2012. We examine the information transfer with different k, especially k = 3, k = 5 and k = 7. Analysis indicates that the cases with k = 3 and k = 7 show the opposite trends but similar characteristics. Change in transfer entropy for intra-structure of CDS market precedes that of stock market in view of the entire time windows. Abrupt rise and fall in inter-structural information transfer between two markets are detected at the periods related to the financial crises, which can be considered as early warnings.

  5. The transfer and transformation of collective network information in gene-matched networks.

    PubMed

    Kitsukawa, Takashi; Yagi, Takeshi

    2015-10-09

    Networks, such as the human society network, social and professional networks, and biological system networks, contain vast amounts of information. Information signals in networks are distributed over nodes and transmitted through intricately wired links, making the transfer and transformation of such information difficult to follow. Here we introduce a novel method for describing network information and its transfer using a model network, the Gene-matched network (GMN), in which nodes (neurons) possess attributes (genes). In the GMN, nodes are connected according to their expression of common genes. Because neurons have multiple genes, the GMN is cluster-rich. We show that, in the GMN, information transfer and transformation were controlled systematically, according to the activity level of the network. Furthermore, information transfer and transformation could be traced numerically with a vector using genes expressed in the activated neurons, the active-gene array, which was used to assess the relative activity among overlapping neuronal groups. Interestingly, this coding style closely resembles the cell-assembly neural coding theory. The method introduced here could be applied to many real-world networks, since many systems, including human society and various biological systems, can be represented as a network of this type.

  6. A flight test facility design for examining digital information transfer

    NASA Technical Reports Server (NTRS)

    Knox, Charles E.

    1990-01-01

    Information is given in viewgraph form on a flight test facility design for examining digital information transfer. Information is given on aircraft/ground exchange, data link research activities, data link display format, a data link flight test, and the flight test setup.

  7. Informal Care and Inter-vivos Transfers: Results from the National Longitudinal Survey of Mature Women

    PubMed Central

    Norton, Edward C.; Nicholas, Lauren H.; Huang, Sean Sheng-Hsiu

    2013-01-01

    Informal care is the largest source of long-term care for elderly, surpassing home health care and nursing home care. By definition, informal care is unpaid. It remains a puzzle why so many adult children give freely of their time. Transfers of time to the older generation may be balanced by financial transfers going to the younger generation. This leads to the question of whether informal care and inter-vivos transfers are causally related. We analyze data from the 1999 and 2003 waves of National Longitudinal Survey of Mature Women. We examine whether the elderly parents give more inter-vivos monetary transfers to adult children who provide informal care, by examining both the extensive and intensive margins of financial transfers and of informal care. We find statistically significant results that a child who provides informal care is more likely to receive inter-vivos transfers than a sibling who does not. If a child does provide care, there is no statistically significant effect on the amount of the transfer. PMID:25285181

  8. Information transfer and information modification to identify the structure of cardiovascular and cardiorespiratory networks.

    PubMed

    Faes, Luca; Nollo, Giandomenico; Krohova, Jana; Czippelova, Barbora; Turianikova, Zuzana; Javorka, Michal

    2017-07-01

    To fully elucidate the complex physiological mechanisms underlying the short-term autonomic regulation of heart period (H), systolic and diastolic arterial pressure (S, D) and respiratory (R) variability, the joint dynamics of these variables need to be explored using multivariate time series analysis. This study proposes the utilization of information-theoretic measures to measure causal interactions between nodes of the cardiovascular/cardiorespiratory network and to assess the nature (synergistic or redundant) of these directed interactions. Indexes of information transfer and information modification are extracted from the H, S, D and R series measured from healthy subjects in a resting state and during postural stress. Computations are performed in the framework of multivariate linear regression, using bootstrap techniques to assess on a single-subject basis the statistical significance of each measure and of its transitions across conditions. We find patterns of information transfer and modification which are related to specific cardiovascular and cardiorespiratory mechanisms in resting conditions and to their modification induced by the orthostatic stress.

  9. Informal care motivations and intergenerational transfers in European countries.

    PubMed

    Jiménez-Martín, Sergi; Vilaplana Prieto, Cristina

    2015-03-01

    This work sets out to analyze the motivations adult children may have to provide informal care, considering the monetary transfers they receive from their parents. Traditional motivations, such as altruism and exchange, are matched against more recent social bond theories. Our findings indicate that informal caregivers receive less frequent and less generous transfers than non-caregivers; that is, caregivers are more prone to suppress their self-interested motivations in order to prioritize the well being of another person. Additionally, long-term public care benefits increase both the probability of receiving a transfer and its amount, with this effect being more intense for both the poorest and richest households. Our findings suggest that if long-term care benefits are intended to increase the recipients' welfare and represent a higher fraction of total income for the poorest households, the effectiveness of these long-term care policies may be diluted. Copyright © 2015 John Wiley & Sons, Ltd.

  10. Quantifying family dissemination and identifying barriers to communication of risk information in Australian BRCA families.

    PubMed

    Healey, Emma; Taylor, Natalie; Greening, Sian; Wakefield, Claire E; Warwick, Linda; Williams, Rachel; Tucker, Kathy

    2017-12-01

    PurposeRecommendations for BRCA1 and BRCA2 mutation carriers to disseminate information to at-risk relatives pose significant challenges. This study aimed to quantify family dissemination, to explain the differences between fully informed families (all relatives informed verbally or in writing) and partially informed families (at least one relative uninformed), and to identify dissemination barriers.MethodsBRCA1 and BRCA2 mutation carriers identified from four Australian hospitals (n=671) were invited to participate in the study. Distress was measured at consent using the Kessler psychological distress scale (K10). A structured telephone interview was used to assess the informed status of relatives, geographical location of relatives, and dissemination barriers. Family dissemination was quantified, and fully versus partially informed family differences were examined. Dissemination barriers were thematically coded and counted.ResultsA total of 165 families participated. Information had been disseminated to 81.1% of relatives. At least one relative had not been informed in 52.7% of families, 4.3% were first-degree relatives, 27.0% were second-degree relatives, and 62.0% were cousins. Partially informed families were significantly larger than fully informed families, had fewer relatives living in close proximity, and exhibited higher levels of distress. The most commonly recorded barrier to dissemination was loss of contact.ConclusionLarger, geographically diverse families have greater difficulty disseminating BRCA mutation risk information to all relatives. Understanding these challenges can inform future initiatives for communication, follow-up and support.

  11. Financial time series analysis based on effective phase transfer entropy

    NASA Astrophysics Data System (ADS)

    Yang, Pengbo; Shang, Pengjian; Lin, Aijing

    2017-02-01

    Transfer entropy is a powerful technique which is able to quantify the impact of one dynamic system on another system. In this paper, we propose the effective phase transfer entropy method based on the transfer entropy method. We use simulated data to test the performance of this method, and the experimental results confirm that the proposed approach is capable of detecting the information transfer between the systems. We also explore the relationship between effective phase transfer entropy and some variables, such as data size, coupling strength and noise. The effective phase transfer entropy is positively correlated with the data size and the coupling strength. Even in the presence of a large amount of noise, it can detect the information transfer between systems, and it is very robust to noise. Moreover, this measure is indeed able to accurately estimate the information flow between systems compared with phase transfer entropy. In order to reflect the application of this method in practice, we apply this method to financial time series and gain new insight into the interactions between systems. It is demonstrated that the effective phase transfer entropy can be used to detect some economic fluctuations in the financial market. To summarize, the effective phase transfer entropy method is a very efficient tool to estimate the information flow between systems.

  12. Electromagnetic information transfer through aqueous system.

    PubMed

    Foletti, Alberto; Ledda, Mario; Lolli, Maria Grazia; Grimaldi, Settimio; Lisi, Antonella

    2017-01-01

    Several beneficial effects of the electromagnetic information transfer through aqueous system (EMITTAS) procedure have previously been reported in vitro. The clinical potential of this procedure has also started to be evaluated. Information flow in biological systems can be investigated through chemical and molecular approaches or by a biophysical approach focused on endogenous electrodynamic activities. Electromagnetic signals are endogenously generated at different levels of the biological organization and, likely, play an active role in synchronizing internal cell function or local/systemic adaptive response. Consequently, each adaptive response can be described by its specific electromagnetic pattern and, therefore, correlates with a unique and specific electromagnetic signature. A biophysical procedure synchronously integrating the EMITTAS procedure has already been applied for the treatment of articular pain, low-back pain, neck pain and mobility, fluctuating asymmetry, early-stage chronic kidney disease, refractory gynecological infections, minor anxiety and depression disorders. This clinical strategy involves a single treatment, since the EMITTAS procedure allows the patient to continue his/her own personal treatment at home by means of self-administration of the recorded aqueous system. A significant and long-lasting improvement has been reported, showing a potential beneficial use of this biophysical procedure in the management of common illnesses in an efficient, effective and personalized way. Data from recent studies suggest that aqueous systems may play a key role in providing the basis for recording, storing, transferring and retrieving clinically effective quanta of biological information. These features likely enable to trigger local and systemic self-regulation and self-regeneration potential of the organism.

  13. Information transfer network of global market indices

    NASA Astrophysics Data System (ADS)

    Kim, Yup; Kim, Jinho; Yook, Soon-Hyung

    2015-07-01

    We study the topological properties of the information transfer networks (ITN) of the global financial market indices for six different periods. ITN is a directed weighted network, in which the direction and weight are determined by the transfer entropy between market indices. By applying the threshold method, it is found that ITN undergoes a crossover from the complete graph to a small-world (SW) network. SW regime of ITN for a global crisis is found to be much more enhanced than that for ordinary periods. Furthermore, when ITN is in SW regime, the average clustering coefficient is found to be synchronized with average volatility of markets. We also compare the results with the topological properties of correlation networks.

  14. Transfer in Artificial Grammar Learning: The Role of Repetition Information

    ERIC Educational Resources Information Center

    Lotz, Anja; Kinder, Annette

    2006-01-01

    In this article, the authors report 2 experiments that investigated the sources of information used in transfer and nontransfer tasks in artificial grammar learning. Multiple regression analyses indicated that 2 types of information about repeating elements were crucial for performance in both tasks: information about the repetition of adjacent…

  15. Information Transfer Analysis of Spontaneous Low-frequency Fluctuations in Cerebral Hemodynamics and Cardiovascular Dynamics

    NASA Astrophysics Data System (ADS)

    Katura, Takusige; Tanaka, Naoki; Obata, Akiko; Sato, Hiroki; Maki, Atsushi

    2005-08-01

    In this study, from the information-theoretic viewpoint, we analyzed the interrelation between the spontaneous low-frequency fluctuations around 0.1Hz in the hemoglobin concentration in the cerebral cortex, mean arterial blood pressure and the heart rate. For this analysis, as measures of information transfer, we used transfer entropy (TE) proposed for two-factor systems by Schreiber and intrinsic transfer entropy (ITE) introduced for further analysis of three-factor systems by extending the original TE. In our analysis, information transfer analysis based on both TE and ITE suggests the systemic cardiovascular fluctuations alone cannot account for the cerebrovascular fluctuations, that is, the regulation of the regional cerebral energetic metabolism is important as a candidate of its generation mechanism Such an information transfer analysis seems useful to reveal the interrelation between the elements regulated each other in a complex manner.

  16. Children's interpretations of general quantifiers, specific quantifiers, and generics

    PubMed Central

    Gelman, Susan A.; Leslie, Sarah-Jane; Was, Alexandra M.; Koch, Christina M.

    2014-01-01

    Recently, several scholars have hypothesized that generics are a default mode of generalization, and thus that young children may at first treat quantifiers as if they were generic in meaning. To address this issue, the present experiment provides the first in-depth, controlled examination of the interpretation of generics compared to both general quantifiers ("all Xs", "some Xs") and specific quantifiers ("all of these Xs", "some of these Xs"). We provided children (3 and 5 years) and adults with explicit frequency information regarding properties of novel categories, to chart when "some", "all", and generics are deemed appropriate. The data reveal three main findings. First, even 3-year-olds distinguish generics from quantifiers. Second, when children make errors, they tend to be in the direction of treating quantifiers like generics. Third, children were more accurate when interpreting specific versus general quantifiers. We interpret these data as providing evidence for the position that generics are a default mode of generalization, especially when reasoning about kinds. PMID:25893205

  17. Exosomes and microvesicles: extracellular vesicles for genetic information transfer and gene therapy.

    PubMed

    Lee, Yi; El Andaloussi, Samir; Wood, Matthew J A

    2012-10-15

    Exosomes and microvesicles are extracellular nanovesicles released by most but not all cells. They are specifically equipped to mediate intercellular communication via the transfer of genetic information, including the transfer of both coding and non-coding RNAs, to recipient cells. As a result, both exosomes and microvesicles play a fundamental biological role in the regulation of normal physiological as well as aberrant pathological processes, via altered gene regulatory networks and/or via epigenetic programming. For example, microvesicle-mediated genetic transfer can regulate the maintenance of stem cell plasticity and induce beneficial cell phenotype modulation. Alternatively, such vesicles play a role in tumor pathogenesis and the spread of neurodegenerative diseases via the transfer of specific microRNAs and pathogenic proteins. Given this natural property for genetic information transfer, the possibility of exploiting these vesicles for therapeutic purposes is now being investigated. Stem cell-derived microvesicles appear to be naturally equipped to mediate tissue regeneration under certain conditions, while recent evidence suggests that exosomes might be harnessed for the targeted delivery of human genetic therapies via the introduction of exogenous genetic cargoes such as siRNA. Thus, extracellular vesicles are emerging as potent genetic information transfer agents underpinning a range of biological processes and with therapeutic potential.

  18. Information Transfer and the Adoption of Agricultural Innovations.

    ERIC Educational Resources Information Center

    Longo, Rose Mary Juliano

    1990-01-01

    Data collected in the Federal District of Brazil were analyzed in terms of information transfer through mass media and interpersonal communication and how they influence farmers in the Federal District of Brazil in their decisions to adopt agricultural innovations. (42 references) (EAM)

  19. A new approach to quantify and map carbon stored, sequestered and emissions avoided by urban forests

    Treesearch

    E. Gregory McPherson; Qingfu Xiao; Elena Aguaron

    2013-01-01

    This paper describes the use of field surveys, biometric information for urban tree species and remote sensing to quantify and map carbon (C) storage, sequestration and avoided emissions from energy savings. Its primary contribution is methodological; the derivation and application of urban tree canopy (UTC) based transfer functions (t C ha-1 UTC). Findings for Los...

  20. 21 CFR 1306.25 - Transfer between pharmacies of prescription information for Schedules III, IV, and V controlled...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... between two licensed pharmacists and the transferring pharmacist records the following information: (i... transferred and the name of the pharmacist receiving the prescription information. (iii) Record the date of the transfer and the name of the pharmacist transferring the information. (b) The pharmacist receiving...

  1. 75 FR 26268 - Agency Information Collection Activities: Permit To Transfer Containers to a Container Station

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-11

    ... Activities: Permit To Transfer Containers to a Container Station AGENCY: U.S. Customs and Border Protection... information collection requirement concerning the: Permit to Transfer Containers to a Container Station. This... information collection: Title: Permit to Transfer Containers to a Container Station. OMB Number: 1651-0049...

  2. Long-Range Reduced Predictive Information Transfers of Autistic Youths in EEG Sensor-Space During Face Processing.

    PubMed

    Khadem, Ali; Hossein-Zadeh, Gholam-Ali; Khorrami, Anahita

    2016-03-01

    The majority of previous functional/effective connectivity studies conducted on the autistic patients converged to the underconnectivity theory of ASD: "long-range underconnectivity and sometimes short-rang overconnectivity". However, to the best of our knowledge the total (linear and nonlinear) predictive information transfers (PITs) of autistic patients have not been investigated yet. Also, EEG data have rarely been used for exploring the information processing deficits in autistic subjects. This study is aimed at comparing the total (linear and nonlinear) PITs of autistic and typically developing healthy youths during human face processing by using EEG data. The ERPs of 12 autistic youths and 19 age-matched healthy control (HC) subjects were recorded while they were watching upright and inverted human face images. The PITs among EEG channels were quantified using two measures separately: transfer entropy with self-prediction optimality (TESPO), and modified transfer entropy with self-prediction optimality (MTESPO). Afterwards, the directed differential connectivity graphs (dDCGs) were constructed to characterize the significant changes in the estimated PITs of autistic subjects compared with HC ones. By using both TESPO and MTESPO, long-range reduction of PITs of ASD group during face processing was revealed (particularly from frontal channels to right temporal channels). Also, it seemed the orientation of face images (upright or upside down) did not modulate the binary pattern of PIT-based dDCGs, significantly. Moreover, compared with TESPO, the results of MTESPO were more compatible with the underconnectivity theory of ASD in the sense that MTESPO showed no long-range increase in PIT. It is also noteworthy that to the best of our knowledge it is the first time that a version of MTE is applied for patients (here ASD) and it is also its first use for EEG data analysis.

  3. Information Transfer in the Brain: Insights from a Unified Approach

    NASA Astrophysics Data System (ADS)

    Marinazzo, Daniele; Wu, Guorong; Pellicoro, Mario; Stramaglia, Sebastiano

    Measuring directed interactions in the brain in terms of information flow is a promising approach, mathematically treatable and amenable to encompass several methods. In this chapter we propose some approaches rooted in this framework for the analysis of neuroimaging data. First we will explore how the transfer of information depends on the network structure, showing how for hierarchical networks the information flow pattern is characterized by exponential distribution of the incoming information and a fat-tailed distribution of the outgoing information, as a signature of the law of diminishing marginal returns. This was reported to be true also for effective connectivity networks from human EEG data. Then we address the problem of partial conditioning to a limited subset of variables, chosen as the most informative ones for the driver node.We will then propose a formal expansion of the transfer entropy to put in evidence irreducible sets of variables which provide information for the future state of each assigned target. Multiplets characterized by a large contribution to the expansion are associated to informational circuits present in the system, with an informational character (synergetic or redundant) which can be associated to the sign of the contribution. Applications are reported for EEG and fMRI data.

  4. 75 FR 43536 - Agency Information Collection Activities: Permit To Transfer Containers to a Container Station

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-26

    ... Activities: Permit To Transfer Containers to a Container Station AGENCY: U.S. Customs and Border Protection... Transfer Containers to a Container Station. This is a proposed extension of an information collection that... other technological techniques or other forms of information. Title: Permit to Transfer Containers to a...

  5. The cost of concreteness: the effect of nonessential information on analogical transfer.

    PubMed

    Kaminski, Jennifer A; Sloutsky, Vladimir M; Heckler, Andrew F

    2013-03-01

    Most theories of analogical transfer focus on similarities between the learning and transfer domains, where transfer is more likely between domains that share common surface features, similar elements, or common interpretations of structure. We suggest that characteristics of the learning instantiation alone can give rise to different levels of transfer. We propose that concreteness of the learning instantiation can hinder analogical transfer of well-defined structured concepts, such as mathematical concepts. We operationalize the term concreteness as the amount of information communicated through a specific instantiation of a concept. The 5 reported experiments with undergraduate students tested the hypothesis by presenting participants with the concept of a commutative mathematical group of order 3. The experiments varied the level of concreteness of the training instantiation and measured transfer of learning to a new instantiation. The results support the hypothesis, demonstrating better transfer from more generic instantiations (i.e., ones that communicate minimal extraneous information) than from more concrete instantiations. Specifically, concreteness was found to create an obstacle to successful structural alignment across domains, whereas generic instantiations led to spontaneous structural alignment. These findings have important implications for the theory of learning and transfer and practical implications for the design of educational material. Although some concreteness may activate prior knowledge and perhaps offer a leg up in the learning process, this benefit may come at the cost of transfer.

  6. Across-horizon scattering and information transfer

    NASA Astrophysics Data System (ADS)

    Emelyanov, V. A.; Klinkhamer, F. R.

    2018-06-01

    We address the question whether or not two electrically charged elementary particles can Coulomb scatter if one of these particles is inside the Schwarzschild black-hole horizon and the other outside. It can be shown that the quantum process is consistent with the local energy–momentum conservation law. This result implies that across-horizon scattering is a physical effect, relevant to astrophysical black holes. We propose a Gedankenexperiment which uses the quantum scattering process to transfer information from inside the black-hole horizon to outside.

  7. Unified framework for information integration based on information geometry

    PubMed Central

    Oizumi, Masafumi; Amari, Shun-ichi

    2016-01-01

    Assessment of causal influences is a ubiquitous and important subject across diverse research fields. Drawn from consciousness studies, integrated information is a measure that defines integration as the degree of causal influences among elements. Whereas pairwise causal influences between elements can be quantified with existing methods, quantifying multiple influences among many elements poses two major mathematical difficulties. First, overestimation occurs due to interdependence among influences if each influence is separately quantified in a part-based manner and then simply summed over. Second, it is difficult to isolate causal influences while avoiding noncausal confounding influences. To resolve these difficulties, we propose a theoretical framework based on information geometry for the quantification of multiple causal influences with a holistic approach. We derive a measure of integrated information, which is geometrically interpreted as the divergence between the actual probability distribution of a system and an approximated probability distribution where causal influences among elements are statistically disconnected. This framework provides intuitive geometric interpretations harmonizing various information theoretic measures in a unified manner, including mutual information, transfer entropy, stochastic interaction, and integrated information, each of which is characterized by how causal influences are disconnected. In addition to the mathematical assessment of consciousness, our framework should help to analyze causal relationships in complex systems in a complete and hierarchical manner. PMID:27930289

  8. Quantifying energy and mass transfer in crop canopies: sensors for measurement of temperature and air velocity

    NASA Technical Reports Server (NTRS)

    Bugbee, B.; Monje, O.; Tanner, B.

    1996-01-01

    Here we report on the in situ performance of inexpensive, miniature sensors that have increased our ability to measure mass and energy fluxes from plant canopies in controlled environments: 1. Surface temperature. Canopy temperature measurements indicate changes in stomatal aperture and thus latent and sensible heat fluxes. Infrared transducers from two manufacturers (Exergen Corporation, Newton, MA; and Everest Interscience, Tucson, AZ, USA) have recently become available. Transducer accuracy matched that of a more expensive hand-held infrared thermometer. 2. Air velocity varies above and within plant canopies and is an important component in mass and energy transfer models. We tested commercially-available needle, heat-transfer anemometers (1 x 50 mm cylinder) that consist of a fine-wire thermocouple and a heater inside a hypodermic needle. The needle is heated and wind speed determined from the temperature rise above ambient. These sensors are particularly useful in measuring the low wind speeds found within plant canopies. 3. Accurate measurements of air temperature adjacent to plant leaves facilitates transport phenomena modeling. We quantified the effect of radiation and air velocity on temperature rise in thermocouples from 10 to 500 micrometers. At high radiation loads and low wind speeds, temperature errors were as large as 7 degrees C above air temperature.

  9. The dynamics of information-driven coordination phenomena: A transfer entropy analysis

    PubMed Central

    Borge-Holthoefer, Javier; Perra, Nicola; Gonçalves, Bruno; González-Bailón, Sandra; Arenas, Alex; Moreno, Yamir; Vespignani, Alessandro

    2016-01-01

    Data from social media provide unprecedented opportunities to investigate the processes that govern the dynamics of collective social phenomena. We consider an information theoretical approach to define and measure the temporal and structural signatures typical of collective social events as they arise and gain prominence. We use the symbolic transfer entropy analysis of microblogging time series to extract directed networks of influence among geolocalized subunits in social systems. This methodology captures the emergence of system-level dynamics close to the onset of socially relevant collective phenomena. The framework is validated against a detailed empirical analysis of five case studies. In particular, we identify a change in the characteristic time scale of the information transfer that flags the onset of information-driven collective phenomena. Furthermore, our approach identifies an order-disorder transition in the directed network of influence between social subunits. In the absence of clear exogenous driving, social collective phenomena can be represented as endogenously driven structural transitions of the information transfer network. This study provides results that can help define models and predictive algorithms for the analysis of societal events based on open source data. PMID:27051875

  10. The dynamics of information-driven coordination phenomena: A transfer entropy analysis.

    PubMed

    Borge-Holthoefer, Javier; Perra, Nicola; Gonçalves, Bruno; González-Bailón, Sandra; Arenas, Alex; Moreno, Yamir; Vespignani, Alessandro

    2016-04-01

    Data from social media provide unprecedented opportunities to investigate the processes that govern the dynamics of collective social phenomena. We consider an information theoretical approach to define and measure the temporal and structural signatures typical of collective social events as they arise and gain prominence. We use the symbolic transfer entropy analysis of microblogging time series to extract directed networks of influence among geolocalized subunits in social systems. This methodology captures the emergence of system-level dynamics close to the onset of socially relevant collective phenomena. The framework is validated against a detailed empirical analysis of five case studies. In particular, we identify a change in the characteristic time scale of the information transfer that flags the onset of information-driven collective phenomena. Furthermore, our approach identifies an order-disorder transition in the directed network of influence between social subunits. In the absence of clear exogenous driving, social collective phenomena can be represented as endogenously driven structural transitions of the information transfer network. This study provides results that can help define models and predictive algorithms for the analysis of societal events based on open source data.

  11. Exosome-Mediated Genetic Information Transfer, a Missing Piece of Osteoblast-Osteoclast Communication Puzzle.

    PubMed

    Yin, Pengbin; Lv, Houchen; Li, Yi; Deng, Yuan; Zhang, Licheng; Tang, Peifu

    2017-01-01

    The skeletal system functions and maintains itself based on communication between cells of diverse origins, especially between osteoblasts (OBs) and osteoclasts (OCs), accounting for bone formation and resorption, respectively. Previously, protein-level information exchange has been the research focus, and this has been discussed in detail. The regulative effects of microRNAs (miRNAs) on OB and OC ignite the question as to whether genetic information could be transferred between bone cells. Exosomes, extracellular membrane vesicles 30-100 nm in diameter, have recently been demonstrated to transfer functional proteins, mRNAs, and miRNAs, and serve as mediators of intercellular communication. By reviewing the distinguishing features of exosomes, a hypothesis was formulated and evaluated in this article that exosome-mediated genetic information transfer may represent a novel strategy for OB-OC communication. The exosomes may coordinately regulate these two cells under certain physiological conditions by transferring genetic information. Further research in exosome-shuttered miRNAs in OB-OC communication may add a missing piece to the bone cells communication "puzzle."

  12. Nonlocal Quantum Information Transfer Without Superluminal Signalling and Communication

    NASA Astrophysics Data System (ADS)

    Walleczek, Jan; Grössing, Gerhard

    2016-09-01

    It is a frequent assumption that—via superluminal information transfers—superluminal signals capable of enabling communication are necessarily exchanged in any quantum theory that posits hidden superluminal influences. However, does the presence of hidden superluminal influences automatically imply superluminal signalling and communication? The non-signalling theorem mediates the apparent conflict between quantum mechanics and the theory of special relativity. However, as a `no-go' theorem there exist two opposing interpretations of the non-signalling constraint: foundational and operational. Concerning Bell's theorem, we argue that Bell employed both interpretations, and that he finally adopted the operational position which is associated often with ontological quantum theory, e.g., de Broglie-Bohm theory. This position we refer to as "effective non-signalling". By contrast, associated with orthodox quantum mechanics is the foundational position referred to here as "axiomatic non-signalling". In search of a decisive communication-theoretic criterion for differentiating between "axiomatic" and "effective" non-signalling, we employ the operational framework offered by Shannon's mathematical theory of communication, whereby we distinguish between Shannon signals and non-Shannon signals. We find that an effective non-signalling theorem represents two sub-theorems: (1) Non-transfer-control (NTC) theorem, and (2) Non-signification-control (NSC) theorem. Employing NTC and NSC theorems, we report that effective, instead of axiomatic, non-signalling is entirely sufficient for prohibiting nonlocal communication. Effective non-signalling prevents the instantaneous, i.e., superluminal, transfer of message-encoded information through the controlled use—by a sender-receiver pair —of informationally-correlated detection events, e.g., in EPR-type experiments. An effective non-signalling theorem allows for nonlocal quantum information transfer yet—at the same time

  13. ­Understanding Information Flow Interaction along Separable Causal Paths in Environmental Signals

    NASA Astrophysics Data System (ADS)

    Jiang, P.; Kumar, P.

    2017-12-01

    Multivariate environmental signals reflect the outcome of complex inter-dependencies, such as those in ecohydrologic systems. Transfer entropy and information partitioning approaches have been used to characterize such dependencies. However, these approaches capture net information flow occurring through a multitude of pathways involved in the interaction and as a result mask our ability to discern the causal interaction within an interested subsystem through specific pathways. We build on recent developments of momentary information transfer along causal paths proposed by Runge [2015] to develop a framework for quantifying information decomposition along separable causal paths. Momentary information transfer along causal paths captures the amount of information flow between any two variables lagged at two specific points in time. Our approach expands this concept to characterize the causal interaction in terms of synergistic, unique and redundant information flow through separable causal paths. Multivariate analysis using this novel approach reveals precise understanding of causality and feedback. We illustrate our approach with synthetic and observed time series data. We believe the proposed framework helps better delineate the internal structure of complex systems in geoscience where huge amounts of observational datasets exist, and it will also help the modeling community by providing a new way to look at the complexity of real and modeled systems. Runge, Jakob. "Quantifying information transfer and mediation along causal pathways in complex systems." Physical Review E 92.6 (2015): 062829.

  14. Bringing Down the Barriers to Information Transfer (L’Abaissement des Barrieres s’Opposant au Transfert de l’Information)

    DTIC Science & Technology

    1992-02-01

    FRANCE AGARD CONFERENCE PROCEEDINGS 505 Bringing down the Barriers to Information Transfer (LAbaissement des Barrires s’Opposant au ’Transfert de ...NEUILLY SUR SEINE FRANCE AGARD CONFERENCE PROCEEDINGS 505 Bringing down the Barriers to Information Transfer (LAbaissement des Barri~res s’Opposant au...Transfert de I’Information) Papers presented at the Technical Information Panel Specialists’ Meeting held at the Instituto Nacional de Industria, Madrid

  15. Interhemispheric Transfer Time Asymmetry of Visual Information Depends on Eye Dominance: An Electrophysiological Study

    PubMed Central

    Chaumillon, Romain; Blouin, Jean; Guillaume, Alain

    2018-01-01

    The interhemispheric transfer of information is a fundamental process in the human brain. When a visual stimulus appears eccentrically in one visual-hemifield, it will first activate the contralateral hemisphere but also the ipsilateral one with a slight delay due to the interhemispheric transfer. This interhemispheric transfer of visual information is believed to be faster from the right to the left hemisphere in right-handers. Such an asymmetry is considered as a relevant fact in the context of the lateralization of the human brain. We show here using current source density (CSD) analyses of visually evoked potential (VEP) that, in right-handers and, to a lesser extent in left-handers, this asymmetry is in fact dependent on the sighting eye dominance, the tendency we have to prefer one eye for monocular tasks. Indeed, in right-handers, a faster interhemispheric transfer of visual information from the right to left hemisphere was observed only in participants with a right dominant eye (DE). Right-handers with a left DE showed the opposite pattern, with a faster transfer from the left to the right hemisphere. In left-handers, albeit a smaller number of participants has been tested and hence confirmation is required, only those with a right DE showed an asymmetrical interhemispheric transfer with a faster transfer from the right to the left hemisphere. As a whole these results demonstrate that eye dominance is a fundamental determinant of asymmetries in interhemispheric transfer of visual information and suggest that it is an important factor of brain lateralization. PMID:29515351

  16. Interhemispheric Transfer Time Asymmetry of Visual Information Depends on Eye Dominance: An Electrophysiological Study.

    PubMed

    Chaumillon, Romain; Blouin, Jean; Guillaume, Alain

    2018-01-01

    The interhemispheric transfer of information is a fundamental process in the human brain. When a visual stimulus appears eccentrically in one visual-hemifield, it will first activate the contralateral hemisphere but also the ipsilateral one with a slight delay due to the interhemispheric transfer. This interhemispheric transfer of visual information is believed to be faster from the right to the left hemisphere in right-handers. Such an asymmetry is considered as a relevant fact in the context of the lateralization of the human brain. We show here using current source density (CSD) analyses of visually evoked potential (VEP) that, in right-handers and, to a lesser extent in left-handers, this asymmetry is in fact dependent on the sighting eye dominance, the tendency we have to prefer one eye for monocular tasks. Indeed, in right-handers, a faster interhemispheric transfer of visual information from the right to left hemisphere was observed only in participants with a right dominant eye (DE). Right-handers with a left DE showed the opposite pattern, with a faster transfer from the left to the right hemisphere. In left-handers, albeit a smaller number of participants has been tested and hence confirmation is required, only those with a right DE showed an asymmetrical interhemispheric transfer with a faster transfer from the right to the left hemisphere. As a whole these results demonstrate that eye dominance is a fundamental determinant of asymmetries in interhemispheric transfer of visual information and suggest that it is an important factor of brain lateralization.

  17. Transfer of Information from Short- to Long-Term Memory

    ERIC Educational Resources Information Center

    Modigliani, Vito; Seamon, John G.

    1974-01-01

    The present study examined current hypotheses concerning information transfer from short-term memory (STM) to long-term memory (LTM) using a Peterson STM task with word triplets presented over retention intervals of 0, 3, 6, 9, and 18 sec. (Editor)

  18. Quantifying forest fragmentation using Geographic Information Systems and Forest Inventory and Analysis plot data

    Treesearch

    Dacia M. Meneguzzo; Mark H. Hansen

    2009-01-01

    Fragmentation metrics provide a means of quantifying and describing forest fragmentation. The most common method of calculating these metrics is through the use of Geographic Information System software to analyze raster data, such as a satellite or aerial image of the study area; however, the spatial resolution of the imagery has a significant impact on the results....

  19. Effective network inference through multivariate information transfer estimation

    NASA Astrophysics Data System (ADS)

    Dahlqvist, Carl-Henrik; Gnabo, Jean-Yves

    2018-06-01

    Network representation has steadily gained in popularity over the past decades. In many disciplines such as finance, genetics, neuroscience or human travel to cite a few, the network may not directly be observable and needs to be inferred from time-series data, leading to the issue of separating direct interactions between two entities forming the network from indirect interactions coming through its remaining part. Drawing on recent contributions proposing strategies to deal with this problem such as the so-called "global silencing" approach of Barzel and Barabasi or "network deconvolution" of Feizi et al. (2013), we propose a novel methodology to infer an effective network structure from multivariate conditional information transfers. Its core principal is to test the information transfer between two nodes through a step-wise approach by conditioning the transfer for each pair on a specific set of relevant nodes as identified by our algorithm from the rest of the network. The methodology is model free and can be applied to high-dimensional networks with both inter-lag and intra-lag relationships. It outperforms state-of-the-art approaches for eliminating the redundancies and more generally retrieving simulated artificial networks in our Monte-Carlo experiments. We apply the method to stock market data at different frequencies (15 min, 1 h, 1 day) to retrieve the network of US largest financial institutions and then document how bank's centrality measurements relate to bank's systemic vulnerability.

  20. NASA technology transfer network communications and information system: TUNS user survey

    NASA Technical Reports Server (NTRS)

    1992-01-01

    Applied Expertise surveyed the users of the deployed Technology Utilization Network System (TUNS) and surveyed prospective new users in order to gather background information for developing the Concept Document of the system that will upgrade and replace TUNS. Survey participants broadly agree that automated mechanisms for acquiring, managing, and disseminating new technology and spinoff benefits information can and should play an important role in meeting NASA technology utilization goals. However, TUNS does not meet this need for most users. The survey describes a number of systematic improvements that will make it easier to use the technology transfer mechanism, and thus expedite the collection and dissemination of technology information. The survey identified 26 suggestions for enhancing the technology transfer system and related processes.

  1. Information transfer during the universal gravitational decoherence

    NASA Astrophysics Data System (ADS)

    Korbicz, J. K.; Tuziemski, J.

    2017-12-01

    Recently Pikovski et al. (Nat Phys 11:668, 2015) have proposed in an intriguing universal decoherence mechanism, suggesting that gravitation may play a conceptually important role in the quantum-to-classical transition, albeit vanishingly small in everyday situations. Here we analyze information transfer induced by this mechanism. We show that generically on short time-scales, gravitational decoherence leads to a redundant information encoding, which results in a form of objectivization of the center-of-mass position in the gravitational field. We derive the relevant time-scales of this process, given in terms of energy dispersion and quantum Fisher information. As an example we study thermal coherent states and show certain robustness of the effect with the temperature. Finally, we draw an analogy between our objectivization mechanism and the fundamental problem of point individuation in General Relativity as emphasized by the Einstein's Hole argument.

  2. Is there more to communications technology than just information transfer

    NASA Astrophysics Data System (ADS)

    Kaltschmidt, H.

    1980-02-01

    In the present paper, communications is discussed in terms of information transfer among people, among automata, and among people and automata. Communications is treated as a cybernetics problem involving information sources and sinks. The principal signals and components of a communications system are examined, along with frequency- and time-multiplexing, optimal detection, correlators, etc.

  3. Information Literacy and Transfer in Schools: Implications for Teacher Librarians

    ERIC Educational Resources Information Center

    Herring, James E.; Bush, Stephanie J.

    2011-01-01

    This study focuses on the use of the New South Wales (NSW) Department of Education and Training information literacy model in a primary school as the basis for the possible establishment of a culture of transfer of information literacy skills. The study used constructivist grounded analysis to interpret data gathered from teachers and principals.…

  4. Quantifying MLI Thermal Conduction in Cryogenic Applications from Experimental Data

    NASA Astrophysics Data System (ADS)

    Ross, R. G., Jr.

    2015-12-01

    Multilayer Insulation (MLI) uses stacks of low-emittance metalized sheets combined with low-conduction spacer features to greatly reduce the heat transfer to cryogenic applications from higher temperature surrounds. However, as the hot-side temperature decreases from room temperature to cryogenic temperatures, the level of radiant heat transfer drops as the fourth power of the temperature, while the heat transfer by conduction only falls off linearly. This results in cryogenic MLI being dominated by conduction, a quantity that is extremely sensitive to MLI blanket construction and very poorly quantified in the literature. To develop useful quantitative data on cryogenic blanket conduction, multilayer nonlinear heat transfer models are used to analyze extensive heat transfer data measured by Lockheed Palo Alto on their cryogenic dewar MLI and measured by JPL on their spacecraft MLI. The data-fitting aspect of the modeling allows the radiative and conductive thermal properties of the tested blankets to be explicitly quantified. Results are presented showing that MLI conductance varies by a factor of 600 between spacecraft MLI and Lockheed's best cryogenic MLI.

  5. Quantifying How Observations Inform a Numerical Reanalysis of Hawaii

    NASA Astrophysics Data System (ADS)

    Powell, B. S.

    2017-11-01

    When assimilating observations into a model via state-estimation, it is possible to quantify how each observation changes the modeled estimate of a chosen oceanic metric. Using an existing 2 year reanalysis of Hawaii that includes more than 31 million observations from satellites, ships, SeaGliders, and autonomous floats, I assess which observations most improve the estimates of the transport and eddy kinetic energy. When the SeaGliders were in the water, they comprised less than 2.5% of the data, but accounted for 23% of the transport adjustment. Because the model physics constrains advanced state-estimation, the prescribed covariances are propagated in time to identify observation-model covariance. I find that observations that constrain the isopycnal tilt across the transport section provide the greatest impact in the analysis. In the case of eddy kinetic energy, observations that constrain the surface-driven upper ocean have more impact. This information can help to identify optimal sampling strategies to improve both state-estimates and forecasts.

  6. The electronic transfer of information and aerospace knowledge diffusion

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Bishop, Ann P.; Barclay, Rebecca O.; Kennedy, John M.

    1992-01-01

    Increasing reliance on and investment in information technology and electronic networking systems presupposes that computing and information technology will play a motor role in the diffusion of aerospace knowledge. Little is known, however, about actual information technology needs, uses, and problems within the aerospace knowledge diffusion process. The authors state that the potential contributions of information technology to increased productivity and competitiveness will be diminished unless empirically derived knowledge regarding the information-seeking behavior of the members of the social system - those who are producing, transferring, and using scientific and technical information - is incorporated into a new technology policy framework. Research into the use of information technology and electronic networks by U.S. aerospace engineers and scientists, collected as part of a research project designed to study aerospace knowledge diffusion, is presented in support of this assertion.

  7. Quantifying lost information due to covariance matrix estimation in parameter inference

    NASA Astrophysics Data System (ADS)

    Sellentin, Elena; Heavens, Alan F.

    2017-02-01

    Parameter inference with an estimated covariance matrix systematically loses information due to the remaining uncertainty of the covariance matrix. Here, we quantify this loss of precision and develop a framework to hypothetically restore it, which allows to judge how far away a given analysis is from the ideal case of a known covariance matrix. We point out that it is insufficient to estimate this loss by debiasing the Fisher matrix as previously done, due to a fundamental inequality that describes how biases arise in non-linear functions. We therefore develop direct estimators for parameter credibility contours and the figure of merit, finding that significantly fewer simulations than previously thought are sufficient to reach satisfactory precisions. We apply our results to DES Science Verification weak lensing data, detecting a 10 per cent loss of information that increases their credibility contours. No significant loss of information is found for KiDS. For a Euclid-like survey, with about 10 nuisance parameters we find that 2900 simulations are sufficient to limit the systematically lost information to 1 per cent, with an additional uncertainty of about 2 per cent. Without any nuisance parameters, 1900 simulations are sufficient to only lose 1 per cent of information. We further derive estimators for all quantities needed for forecasting with estimated covariance matrices. Our formalism allows to determine the sweetspot between running sophisticated simulations to reduce the number of nuisance parameters, and running as many fast simulations as possible.

  8. Shakespeare and other English Renaissance authors as characterized by Information Theory complexity quantifiers

    NASA Astrophysics Data System (ADS)

    Rosso, Osvaldo A.; Craig, Hugh; Moscato, Pablo

    2009-03-01

    We introduce novel Information Theory quantifiers in a computational linguistic study that involves a large corpus of English Renaissance literature. The 185 texts studied (136 plays and 49 poems in total), with first editions that range from 1580 to 1640, form a representative set of its period. Our data set includes 30 texts unquestionably attributed to Shakespeare; in addition we also included A Lover’s Complaint, a poem which generally appears in Shakespeare collected editions but whose authorship is currently in dispute. Our statistical complexity quantifiers combine the power of Jensen-Shannon’s divergence with the entropy variations as computed from a probability distribution function of the observed word use frequencies. Our results show, among other things, that for a given entropy poems display higher complexity than plays, that Shakespeare’s work falls into two distinct clusters in entropy, and that his work is remarkable for its homogeneity and for its closeness to overall means.

  9. 77 FR 57105 - Notice of Proposed Information Collection: Comment Request; Application for the Transfer of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-17

    ... Information Collection: Comment Request; Application for the Transfer of Physical Assets AGENCY: Office of the... information: Title of Proposal: Application for the Transfer of Physical Assets. OMB Control Number, if... used to ensure that HUD multifamily housing properties are not placed in physical, financial, or...

  10. Report of a Planning Conference for Solar Technology Information Transfer. Austin, Texas, 12-13 June 1979).

    ERIC Educational Resources Information Center

    Southwestern Library Association, Stillwater, OK.

    Charged with the responsibility of determining the best way to plan for solar technology information transfer within the state of Texas, participants in the Planning Conference for Solar Technology Information Transfer met to discuss the many ongoing activities related to energy information dissemination, to analyze the resources available in…

  11. Scientific and Technical Information Transfer for Education (STITE). Research Report No. 2.

    ERIC Educational Resources Information Center

    Zunde, Pranas

    STITE (Scientific and Technical Information Transfer for Education) is basically a system to interface between science information and the science learner. As such STITE acts as a link between STIC (Science and Technology Infromation Centers) and LIS (Learning Information Systems). In this second progress report the internal knowledge of STITE is…

  12. Information transfer satellite concept study. Volume 2: Technical

    NASA Technical Reports Server (NTRS)

    Bergin, P.; Kincade, C.; Kurpiewski, D.; Leinhaupel, F.; Millican, F.; Onstad, R.

    1971-01-01

    The ITS concept study is preceded by two requirements studies whose primary objectives are to identify viable demands and to develop the functional requirements associated with these demands. In addition to continuing this basic activity the ITS concept study objectives are to: (1) develop tools and techniques for planning advanced information transfer satellite communications systems, and to (2) select viable systems for further analysis both in their near-term and in the far-term aspects.

  13. Scientific and Technical Information and Transfer for Education (STITE). Research Report No. 1.

    ERIC Educational Resources Information Center

    Zunde, Pranas

    STITE (Scientific and Technical Information Transfer for Education) is basically a system to interface between science information and the science learner. As such STITE acts as a link between STIC (Science and Technology Information Centers) and LIS (Learning Information Systems). After an introduction to the goals and objectives of the ongoing…

  14. Does similarity in call structure or foraging ecology explain interspecific information transfer in wild Myotis bats?

    PubMed

    Hügel, Theresa; van Meir, Vincent; Muñoz-Meneses, Amanda; Clarin, B-Markus; Siemers, Björn M; Goerlitz, Holger R

    2017-01-01

    Animals can gain important information by attending to the signals and cues of other animals in their environment, with acoustic information playing a major role in many taxa. Echolocation call sequences of bats contain information about the identity and behaviour of the sender which is perceptible to close-by receivers. Increasing evidence supports the communicative function of echolocation within species, yet data about its role for interspecific information transfer is scarce. Here, we asked which information bats extract from heterospecific echolocation calls during foraging. In three linked playback experiments, we tested in the flight room and field if foraging Myotis bats approached the foraging call sequences of conspecifics and four heterospecifics that were similar in acoustic call structure only (acoustic similarity hypothesis), in foraging ecology only (foraging similarity hypothesis), both, or none. Compared to the natural prey capture rate of 1.3 buzzes per minute of bat activity, our playbacks of foraging sequences with 23-40 buzzes/min simulated foraging patches with significantly higher profitability. In the flight room, M. capaccinii only approached call sequences of conspecifics and of the heterospecific M. daubentonii with similar acoustics and foraging ecology. In the field, M. capaccinii and M. daubentonii only showed a weak positive response to those two species. Our results confirm information transfer across species boundaries and highlight the importance of context on the studied behaviour, but cannot resolve whether information transfer in trawling Myotis is based on acoustic similarity only or on a combination of similarity in acoustics and foraging ecology. Animals transfer information, both voluntarily and inadvertently, and within and across species boundaries. In echolocating bats, acoustic call structure and foraging ecology are linked, making echolocation calls a rich source of information about species identity, ecology and

  15. The Fallacy of Quantifying Risk

    DTIC Science & Technology

    2012-09-01

    Defense AT&L: September–October 2012 18 The Fallacy of Quantifying Risk David E. Frick, Ph.D. Frick is a 35-year veteran of the Department of...a key to risk analysis was “choosing the right technique” of quantifying risk . The weakness in this argument stems not from the assertion that one...of information about the enemy), yet achiev- ing great outcomes. Attempts at quantifying risk are not, in and of themselves, objectionable. Prudence

  16. Assessing the Suitability of Process and Information Technology in Supporting Tacit Knowledge Transfer

    ERIC Educational Resources Information Center

    Wu, Chien-Hsing; Kao, Shu-Chen; Shih, Lan-Hsin

    2010-01-01

    The transfer of tacit knowledge, one of the most important issues in the knowledge sharing context, needs a multi-dimensional perception in its process. Information technology's (IT) supporting role has already been addressed in the process of tacit knowledge transfer. However, IT has its own characteristics, and in turn, may have dissimilar…

  17. Students Seeking Access to Four-Year Institutions: Community College Transfers [Background Information].

    ERIC Educational Resources Information Center

    Moore, Jamillah

    This publication provides background information for a hearing by the California Senate Select Committee on Higher Education and Outreach on December 3, 1997. The Introduction presents the Committee announcement, press release, agenda, information about transfer efforts in California, facts and figures about the community colleges, and the text of…

  18. Incorporating both physical and kinetic limitations in quantifying dissolved oxygen flux to aquatic sediments

    USGS Publications Warehouse

    O'Connor, B.L.; Hondzo, Miki; Harvey, J.W.

    2009-01-01

    Traditionally, dissolved oxygen (DO) fluxes have been calculated using the thin-film theory with DO microstructure data in systems characterized by fine sediments and low velocities. However, recent experimental evidence of fluctuating DO concentrations near the sediment-water interface suggests that turbulence and coherent motions control the mass transfer, and the surface renewal theory gives a more mechanistic model for quantifying fluxes. Both models involve quantifying the mass transfer coefficient (k) and the relevant concentration difference (??C). This study compared several empirical models for quantifying k based on both thin-film and surface renewal theories, as well as presents a new method for quantifying ??C (dynamic approach) that is consistent with the observed DO concentration fluctuations near the interface. Data were used from a series of flume experiments that includes both physical and kinetic uptake limitations of the flux. Results indicated that methods for quantifying k and ??C using the surface renewal theory better estimated the DO flux across a range of fluid-flow conditions. ?? 2009 ASCE.

  19. Stochastic information transfer from cochlear implant electrodes to auditory nerve fibers

    NASA Astrophysics Data System (ADS)

    Gao, Xiao; Grayden, David B.; McDonnell, Mark D.

    2014-08-01

    Cochlear implants, also called bionic ears, are implanted neural prostheses that can restore lost human hearing function by direct electrical stimulation of auditory nerve fibers. Previously, an information-theoretic framework for numerically estimating the optimal number of electrodes in cochlear implants has been devised. This approach relies on a model of stochastic action potential generation and a discrete memoryless channel model of the interface between the array of electrodes and the auditory nerve fibers. Using these models, the stochastic information transfer from cochlear implant electrodes to auditory nerve fibers is estimated from the mutual information between channel inputs (the locations of electrodes) and channel outputs (the set of electrode-activated nerve fibers). Here we describe a revised model of the channel output in the framework that avoids the side effects caused by an "ambiguity state" in the original model and also makes fewer assumptions about perceptual processing in the brain. A detailed comparison of how different assumptions on fibers and current spread modes impact on the information transfer in the original model and in the revised model is presented. We also mathematically derive an upper bound on the mutual information in the revised model, which becomes tighter as the number of electrodes increases. We found that the revised model leads to a significantly larger maximum mutual information and corresponding number of electrodes compared with the original model and conclude that the assumptions made in this part of the modeling framework are crucial to the model's overall utility.

  20. Transfer and distortion of atmospheric information in the satellite temperature retrieval problem

    NASA Technical Reports Server (NTRS)

    Thompson, O. E.

    1981-01-01

    A systematic approach to investigating the transfer of basic ambient temperature information and its distortion by satellite systems and subsequent analysis algorithms is discussed. The retrieval analysis cycle is derived, the variance spectrum of information is examined as it takes different forms in that process, and the quality and quantity of information existing at each stop is compared with the initial ambient temperature information. Temperature retrieval algorithms can smooth, add, or further distort information, depending on how stable the algorithm is, and how heavily influenced by a priori data.

  1. Novel information theory-based measures for quantifying incongruence among phylogenetic trees.

    PubMed

    Salichos, Leonidas; Stamatakis, Alexandros; Rokas, Antonis

    2014-05-01

    Phylogenies inferred from different data matrices often conflict with each other necessitating the development of measures that quantify this incongruence. Here, we introduce novel measures that use information theory to quantify the degree of conflict or incongruence among all nontrivial bipartitions present in a set of trees. The first measure, internode certainty (IC), calculates the degree of certainty for a given internode by considering the frequency of the bipartition defined by the internode (internal branch) in a given set of trees jointly with that of the most prevalent conflicting bipartition in the same tree set. The second measure, IC All (ICA), calculates the degree of certainty for a given internode by considering the frequency of the bipartition defined by the internode in a given set of trees in conjunction with that of all conflicting bipartitions in the same underlying tree set. Finally, the tree certainty (TC) and TC All (TCA) measures are the sum of IC and ICA values across all internodes of a phylogeny, respectively. IC, ICA, TC, and TCA can be calculated from different types of data that contain nontrivial bipartitions, including from bootstrap replicate trees to gene trees or individual characters. Given a set of phylogenetic trees, the IC and ICA values of a given internode reflect its specific degree of incongruence, and the TC and TCA values describe the global degree of incongruence between trees in the set. All four measures are implemented and freely available in version 8.0.0 and subsequent versions of the widely used program RAxML.

  2. 77 FR 21579 - Agency Information Collection Activities: Transfer of Cargo to a Container Station

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-10

    ... Activities: Transfer of Cargo to a Container Station AGENCY: U.S. Customs and Border Protection, Department... Budget (OMB) for review and approval in accordance with the Paperwork Reduction Act: Transfer of Cargo to a Container Station. This is a proposed extension of an information collection that was previously...

  3. Public information influences sperm transfer to females in sailfin molly males.

    PubMed

    Nöbel, Sabine; Witte, Klaudia

    2013-01-01

    In animals, including humans, the social environment can serve as a public information network in which individuals can gather public information about the quality of potential mates by observing conspecifics during sexual interactions. The observing individual itself is also a part of this information network. When recognized by the observed conspecifics as an audience, his/her presence could influence the sexual interaction between those individuals, because the observer might be considered as a potential mate or competitor. One of the most challenging questions in sexual selection to date is how the use of public information in the context of mate choice is linked to the fitness of individuals. Here, we could show that public information influences mate-choice behaviour in sailfin molly males, Poecilia latipinna, and influences the amount of sperm males transfer to a female partner. In the presence of an audience male, males spent less time with the previously preferred, larger of two females and significantly more time with the previously non-preferred, smaller female. When males could physically interact with a female and were faced with an audience male, three audience females or no audience, males transferred significantly more sperm to a female partner in the presence of an audience male than with female audience or no audience and spent less time courting his female partner. This is the first study showing that public information use turns into fitness investment, which is the crucial factor to understand the role of public information in the dynamic processes in sexual selection.

  4. 49 CFR 8.23 - Classified information transferred to the Department of Transportation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... transferred to the National Archives and Records Administration (NARA) will be declassified or downgraded by... with the Archivist in efforts to establish a Government-wide database of information that has been...

  5. 49 CFR 8.23 - Classified information transferred to the Department of Transportation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... transferred to the National Archives and Records Administration (NARA) will be declassified or downgraded by... with the Archivist in efforts to establish a Government-wide database of information that has been...

  6. 49 CFR 8.23 - Classified information transferred to the Department of Transportation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... transferred to the National Archives and Records Administration (NARA) will be declassified or downgraded by... with the Archivist in efforts to establish a Government-wide database of information that has been...

  7. 49 CFR 8.23 - Classified information transferred to the Department of Transportation.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... transferred to the National Archives and Records Administration (NARA) will be declassified or downgraded by... with the Archivist in efforts to establish a Government-wide database of information that has been...

  8. Spectral Transfer Learning Using Information Geometry for a User-Independent Brain-Computer Interface.

    PubMed

    Waytowich, Nicholas R; Lawhern, Vernon J; Bohannon, Addison W; Ball, Kenneth R; Lance, Brent J

    2016-01-01

    Recent advances in signal processing and machine learning techniques have enabled the application of Brain-Computer Interface (BCI) technologies to fields such as medicine, industry, and recreation; however, BCIs still suffer from the requirement of frequent calibration sessions due to the intra- and inter-individual variability of brain-signals, which makes calibration suppression through transfer learning an area of increasing interest for the development of practical BCI systems. In this paper, we present an unsupervised transfer method (spectral transfer using information geometry, STIG), which ranks and combines unlabeled predictions from an ensemble of information geometry classifiers built on data from individual training subjects. The STIG method is validated in both off-line and real-time feedback analysis during a rapid serial visual presentation task (RSVP). For detection of single-trial, event-related potentials (ERPs), the proposed method can significantly outperform existing calibration-free techniques as well as outperform traditional within-subject calibration techniques when limited data is available. This method demonstrates that unsupervised transfer learning for single-trial detection in ERP-based BCIs can be achieved without the requirement of costly training data, representing a step-forward in the overall goal of achieving a practical user-independent BCI system.

  9. Intergenerational transfers and informal care for disabled elderly persons in China: evidence from CHARLS.

    PubMed

    Liu, Xiaoting; Lu, Bei; Feng, Zhixin

    2017-07-01

    Aiming at 'ageing healthier and ageing better', a certain amount of high-quality informal care should be available for elderly persons with physical disability as formal care is barely accessible in China. The demographic transition and family structural changes have dramatically weakened traditional norms of filial piety and the structure of intergenerational transfers. This article employed nationwide representative data from the first wave (2011) of Chinese Health and Retirement Longitudinal Study (CHARLS) in order to identify the duration of informal care provision at home for frail elders (1122 in rural areas and 577 in urban areas, total 1699), measured in monthly hours, before estimating the associations between intergenerational transfers and the received time of informal care with Tobit Model analysis. Results showed that financial support from the younger generation was unexpectedly negatively associated with the monthly hours of care, implying a reduction of caring support along with increasing financial transfers towards older parents. The lack of informal care could not be compensated by having more children, co-residing with children, or increasing the parent-to-child/grandchild transfers. Spouses were shown to replace children as the major caregivers. In addition, the community-based long-term care system needs to be promoted to sustain and develop informal care, as the latter will become increasingly important with changing family dynamics. Finally, the received time of informal care, rather than the severity of physical disability measured by difficulty with ADLs or IADLs, was introduced to identify the actual demand for care by elders. The paper argues that it is important to reconceptualise and re-investigate the duration of care provision in the Chinese context in order to develop standards of payment as part of long-term care policies. © 2017 John Wiley & Sons Ltd.

  10. Processing of Numerical and Proportional Quantifiers

    ERIC Educational Resources Information Center

    Shikhare, Sailee; Heim, Stefan; Klein, Elise; Huber, Stefan; Willmes, Klaus

    2015-01-01

    Quantifier expressions like "many" and "at least" are part of a rich repository of words in language representing magnitude information. The role of numerical processing in comprehending quantifiers was studied in a semantic truth value judgment task, asking adults to quickly verify sentences about visual displays using…

  11. The Transfer Achievement Program (TAP): Information Packet.

    ERIC Educational Resources Information Center

    Segura, Armando; Noseworthy, Victoria

    Santa Barbara City College (California) created the Transfer Achievement Program (TAP) to deliver an integrated and cohesive set of services to underrepresented students to help increase their transfer rate to four-year institutions. TAP provides students with a developmental map of transfer-related activities through the use of the Transfer Task…

  12. The Effectiveness and Feasibility of a TRISNET Regional Center in Information Transfer. Final Report.

    ERIC Educational Resources Information Center

    Rath, Gustave J.; And Others

    A study was conducted to assess the feasibility of establishing a regional information transfer center within the context of the National Network of Transportation Research Information Services (TRISNET). The principle areas of investigation were: (1) the transportation information needs of the public and private sectors; (2) the utility of…

  13. Comparative analyses suggest that information transfer promoted sociality in male bats in the temperate zone.

    PubMed

    Safi, Kamran; Kerth, Gerald

    2007-09-01

    The evolution of sociality is a central theme in evolutionary biology. The vast majority of bats are social, which has been explained in terms of the benefits of communal breeding. However, the causes for segregated male groups remain unknown. In a comparative study, we tested whether diet and morphological adaptations to specific foraging styles, two factors known to influence the occurrence of information transfer, can predict male sociality. Our results suggest that the species most likely to benefit from information transfer--namely, those preying on ephemeral insects and with morphological adaptations to feeding in open habitat--are more likely to form male groups. Our findings also indicate that solitary life was the ancestral state of males and sociality evolved in several lineages. Beyond their significance for explaining the existence of male groups in bats, our findings highlight the importance of information transfer in the evolution of animal sociality.

  14. Multiscale Symbolic Phase Transfer Entropy in Financial Time Series Classification

    NASA Astrophysics Data System (ADS)

    Zhang, Ningning; Lin, Aijing; Shang, Pengjian

    We address the challenge of classifying financial time series via a newly proposed multiscale symbolic phase transfer entropy (MSPTE). Using MSPTE method, we succeed to quantify the strength and direction of information flow between financial systems and classify financial time series, which are the stock indices from Europe, America and China during the period from 2006 to 2016 and the stocks of banking, aviation industry and pharmacy during the period from 2007 to 2016, simultaneously. The MSPTE analysis shows that the value of symbolic phase transfer entropy (SPTE) among stocks decreases with the increasing scale factor. It is demonstrated that MSPTE method can well divide stocks into groups by areas and industries. In addition, it can be concluded that the MSPTE analysis quantify the similarity among the stock markets. The symbolic phase transfer entropy (SPTE) between the two stocks from the same area is far less than the SPTE between stocks from different areas. The results also indicate that four stocks from America and Europe have relatively high degree of similarity and the stocks of banking and pharmaceutical industry have higher similarity for CA. It is worth mentioning that the pharmaceutical industry has weaker particular market mechanism than banking and aviation industry.

  15. Quantifying navigational information: The catchment volumes of panoramic snapshots in outdoor scenes.

    PubMed

    Murray, Trevor; Zeil, Jochen

    2017-01-01

    Panoramic views of natural environments provide visually navigating animals with two kinds of information: they define locations because image differences increase smoothly with distance from a reference location and they provide compass information, because image differences increase smoothly with rotation away from a reference orientation. The range over which a given reference image can provide navigational guidance (its 'catchment area') has to date been quantified from the perspective of walking animals by determining how image differences develop across the ground plane of natural habitats. However, to understand the information available to flying animals there is a need to characterize the 'catchment volumes' within which panoramic snapshots can provide navigational guidance. We used recently developed camera-based methods for constructing 3D models of natural environments and rendered panoramic views at defined locations within these models with the aim of mapping navigational information in three dimensions. We find that in relatively open woodland habitats, catchment volumes are surprisingly large extending for metres depending on the sensitivity of the viewer to image differences. The size and the shape of catchment volumes depend on the distance of visual features in the environment. Catchment volumes are smaller for reference images close to the ground and become larger for reference images at some distance from the ground and in more open environments. Interestingly, catchment volumes become smaller when only above horizon views are used and also when views include a 1 km distant panorama. We discuss the current limitations of mapping navigational information in natural environments and the relevance of our findings for our understanding of visual navigation in animals and autonomous robots.

  16. Quantifying navigational information: The catchment volumes of panoramic snapshots in outdoor scenes

    PubMed Central

    Zeil, Jochen

    2017-01-01

    Panoramic views of natural environments provide visually navigating animals with two kinds of information: they define locations because image differences increase smoothly with distance from a reference location and they provide compass information, because image differences increase smoothly with rotation away from a reference orientation. The range over which a given reference image can provide navigational guidance (its ‘catchment area’) has to date been quantified from the perspective of walking animals by determining how image differences develop across the ground plane of natural habitats. However, to understand the information available to flying animals there is a need to characterize the ‘catchment volumes’ within which panoramic snapshots can provide navigational guidance. We used recently developed camera-based methods for constructing 3D models of natural environments and rendered panoramic views at defined locations within these models with the aim of mapping navigational information in three dimensions. We find that in relatively open woodland habitats, catchment volumes are surprisingly large extending for metres depending on the sensitivity of the viewer to image differences. The size and the shape of catchment volumes depend on the distance of visual features in the environment. Catchment volumes are smaller for reference images close to the ground and become larger for reference images at some distance from the ground and in more open environments. Interestingly, catchment volumes become smaller when only above horizon views are used and also when views include a 1 km distant panorama. We discuss the current limitations of mapping navigational information in natural environments and the relevance of our findings for our understanding of visual navigation in animals and autonomous robots. PMID:29088300

  17. Sources and Information on Transfer Associate Degrees

    ERIC Educational Resources Information Center

    Ayon, Carlos

    2012-01-01

    This chapter provides an annotated bibliography of articles about the effects of transfer associate degrees and related statewide transfer and articulation policies. It also provides links to transfer degree legislation in several states.

  18. Measuring the jitter of ring oscillators by means of information theory quantifiers

    NASA Astrophysics Data System (ADS)

    Antonelli, M.; De Micco, L.; Larrondo, H. A.

    2017-02-01

    Ring oscillators (RO's) are elementary blocks widely used in digital design. Jitter is unavoidable in RO's, its presence is an undesired behavior in many applications, as clock generators. On the contrary, jitter may be used as the noise source in RO-based true-random numbers generators (TRNG). Consequently, jitter measure is a relevant issue to characterize a RO, and it is the subject of this paper. The main contribution is the use of Information Theory Quantifiers (ITQ) as measures of RO's jitter. It is shown that among several ITQ evaluated, two of them emerge as good measures because they are independent of parameters used for their statistical determination. They turned out to be robust and may be implemented experimentally. We encountered that a dual entropy plane allows a visual comparison of results.

  19. 77 FR 4815 - Ace Info Solutions, Inc., and Information International Associates; Transfer of Data

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-31

    ... Confidential Business Information (CBI) by the submitter, will be transferred to Ace Info Solutions, Inc., and... Chemical Libraries and Repository; 4. Information architecture support, consultation on site structure and..., Business and industry, Government contracts, Government property, Security measures. Dated: January 19...

  20. The transferability of information and communication technology skills from university to the workplace: a qualitative descriptive study.

    PubMed

    Bembridge, Elizabeth; Levett-Jones, Tracy; Jeong, Sarah Yeun-Sim

    2011-04-01

    This paper presents the findings from a study that explored whether the information and communication technology (ICT) skills nurses acquired at university are relevant and transferable to contemporary practice environments. Whilst universities have attempted to integrate information and communication technology into nursing curricula it is not known whether the skills developed for educational purposes are relevant or transferable to clinical contexts. A qualitative descriptive study was used to explore the perspectives of a small group of new graduate nurses working in a regional/semi-metropolitan healthcare facility in New South Wales, Australia. Semi-structured interviews were used and the data thematically analysed. The themes that emerged from the study are presented in accordance with the conceptual framework and structured under the three headings of pre-transfer, transition and post-transfer. The transferability of information and communication technology skills from university to the workplace is impacted by a range of educational, individual, organisational and contextual factors. Access to adequate ICT and the necessary training opportunities influences new graduates' work satisfaction and their future employment decisions. The ability to effectively use information and communication technology was viewed as essential to the provision of quality patient care. Copyright © 2010 Elsevier Ltd. All rights reserved.

  1. Spectral Transfer Learning Using Information Geometry for a User-Independent Brain-Computer Interface

    DOE PAGES

    Waytowich, Nicholas R.; Lawhern, Vernon J.; Bohannon, Addison W.; ...

    2016-09-22

    Recent advances in signal processing and machine learning techniques have enabled the application of Brain-Computer Interface (BCI) technologies to fields such as medicine, industry, and recreation; however, BCIs still suffer from the requirement of frequent calibration sessions due to the intra- and inter-individual variability of brain-signals, which makes calibration suppression through transfer learning an area of increasing interest for the development of practical BCI systems. In this paper, we present an unsupervised transfer method (spectral transfer using information geometry,STIG),which ranks and combines unlabeled predictions from an ensemble of information geometry classifiers built on data from individual training subjects. The STIGmore » method is validated in both off-line and real-time feedback analysis during a rapid serial visual presentation task (RSVP). For detection of single-trial, event-related potentials (ERPs), the proposed method can significantly outperform existing calibration-free techniques as well as out perform traditional within-subject calibration techniques when limited data is available. Here, this method demonstrates that unsupervised transfer learning for single-trial detection in ERP-based BCIs can be achieved without the requirement of costly training data, representing a step-forward in the overall goal of achieving a practical user-independent BCI system.« less

  2. Spectral Transfer Learning Using Information Geometry for a User-Independent Brain-Computer Interface

    PubMed Central

    Waytowich, Nicholas R.; Lawhern, Vernon J.; Bohannon, Addison W.; Ball, Kenneth R.; Lance, Brent J.

    2016-01-01

    Recent advances in signal processing and machine learning techniques have enabled the application of Brain-Computer Interface (BCI) technologies to fields such as medicine, industry, and recreation; however, BCIs still suffer from the requirement of frequent calibration sessions due to the intra- and inter-individual variability of brain-signals, which makes calibration suppression through transfer learning an area of increasing interest for the development of practical BCI systems. In this paper, we present an unsupervised transfer method (spectral transfer using information geometry, STIG), which ranks and combines unlabeled predictions from an ensemble of information geometry classifiers built on data from individual training subjects. The STIG method is validated in both off-line and real-time feedback analysis during a rapid serial visual presentation task (RSVP). For detection of single-trial, event-related potentials (ERPs), the proposed method can significantly outperform existing calibration-free techniques as well as outperform traditional within-subject calibration techniques when limited data is available. This method demonstrates that unsupervised transfer learning for single-trial detection in ERP-based BCIs can be achieved without the requirement of costly training data, representing a step-forward in the overall goal of achieving a practical user-independent BCI system. PMID:27713685

  3. Spectral Transfer Learning Using Information Geometry for a User-Independent Brain-Computer Interface

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Waytowich, Nicholas R.; Lawhern, Vernon J.; Bohannon, Addison W.

    Recent advances in signal processing and machine learning techniques have enabled the application of Brain-Computer Interface (BCI) technologies to fields such as medicine, industry, and recreation; however, BCIs still suffer from the requirement of frequent calibration sessions due to the intra- and inter-individual variability of brain-signals, which makes calibration suppression through transfer learning an area of increasing interest for the development of practical BCI systems. In this paper, we present an unsupervised transfer method (spectral transfer using information geometry,STIG),which ranks and combines unlabeled predictions from an ensemble of information geometry classifiers built on data from individual training subjects. The STIGmore » method is validated in both off-line and real-time feedback analysis during a rapid serial visual presentation task (RSVP). For detection of single-trial, event-related potentials (ERPs), the proposed method can significantly outperform existing calibration-free techniques as well as out perform traditional within-subject calibration techniques when limited data is available. Here, this method demonstrates that unsupervised transfer learning for single-trial detection in ERP-based BCIs can be achieved without the requirement of costly training data, representing a step-forward in the overall goal of achieving a practical user-independent BCI system.« less

  4. A DDC Bibliography on Cost/Benefits of Technical Information Services and Technology Transfer.

    ERIC Educational Resources Information Center

    Defense Documentation Center, Alexandria, VA.

    This bibliography is a compilation of literature existing in both the government and public sectors and concerning Cost/Benefits of Technical information Services and Technology Transfer. Not only was the cost-benefit to the user reflected, but consideration was given to the initial cost of information collections, the cost of processing the…

  5. Thermocapillary flow contribution to dropwise condensation heat transfer

    NASA Astrophysics Data System (ADS)

    Phadnis, Akshay; Rykaczewski, Konrad

    2017-11-01

    With recent developments of durable hydrophobic materials potentially enabling industrial applications of dropwise condensation, accurate modeling of heat transfer during this phase change process is becoming increasingly important. Classical steady state models of dropwise condensation are based on the integration of heat transfer through individual droplets over the entire drop size distribution. These models consider only the conduction heat transfer inside the droplets. However, simple scaling arguments suggest that thermocapillary flows might exist in such droplets. In this work, we used Finite Element heat transfer model to quantify the effect of Marangoni flow on dropwise condensation heat transfer of liquids with a wide range of surface tensions ranging from water to pentane. We confirmed that the Marangoni flow is present for a wide range of droplet sizes, but only has quantifiable effects on heat transfer in drops larger than 10 µm. By integrating the single drop heat transfer simulation results with drop size distribution for the cases considered, we demonstrated that Marangoni flow contributes a 10-30% increase in the overall heat transfer coefficient over conduction only model.

  6. Information transfer across the scales of climate data variability

    NASA Astrophysics Data System (ADS)

    Palus, Milan; Jajcay, Nikola; Hartman, David; Hlinka, Jaroslav

    2015-04-01

    Multitude of scales characteristic of the climate system variability requires innovative approaches in analysis of instrumental time series. We present a methodology which starts with a wavelet decomposition of a multi-scale signal into quasi-oscillatory modes of a limited band-with, described using their instantaneous phases and amplitudes. Then their statistical associations are tested in order to search for interactions across time scales. In particular, an information-theoretic formulation of the generalized, nonlinear Granger causality is applied together with surrogate data testing methods [1]. The method [2] uncovers causal influence (in the Granger sense) and information transfer from large-scale modes of climate variability with characteristic time scales from years to almost a decade to regional temperature variability on short time scales. In analyses of daily mean surface air temperature from various European locations an information transfer from larger to smaller scales has been observed as the influence of the phase of slow oscillatory phenomena with periods around 7-8 years on amplitudes of the variability characterized by smaller temporal scales from a few months to annual and quasi-biennial scales [3]. In sea surface temperature data from the tropical Pacific area an influence of quasi-oscillatory phenomena with periods around 4-6 years on the variability on and near the annual scale has been observed. This study is supported by the Ministry of Education, Youth and Sports of the Czech Republic within the Program KONTAKT II, Project No. LH14001. [1] M. Palus, M. Vejmelka, Phys. Rev. E 75, 056211 (2007) [2] M. Palus, Entropy 16(10), 5263-5289 (2014) [3] M. Palus, Phys. Rev. Lett. 112, 078702 (2014)

  7. Diagnosing the Dynamics of Observed and Simulated Ecosystem Gross Primary Productivity with Time Causal Information Theory Quantifiers

    DOE PAGES

    Sippel, Sebastian; Lange, Holger; Mahecha, Miguel D.; ...

    2016-10-20

    Data analysis and model-data comparisons in the environmental sciences require diagnostic measures that quantify time series dynamics and structure, and are robust to noise in observational data. This paper investigates the temporal dynamics of environmental time series using measures quantifying their information content and complexity. The measures are used to classify natural processes on one hand, and to compare models with observations on the other. The present analysis focuses on the global carbon cycle as an area of research in which model-data integration and comparisons are key to improving our understanding of natural phenomena. We investigate the dynamics of observedmore » and simulated time series of Gross Primary Productivity (GPP), a key variable in terrestrial ecosystems that quantifies ecosystem carbon uptake. However, the dynamics, patterns and magnitudes of GPP time series, both observed and simulated, vary substantially on different temporal and spatial scales. Here we demonstrate that information content and complexity, or Information Theory Quantifiers (ITQ) for short, serve as robust and efficient data-analytical and model benchmarking tools for evaluating the temporal structure and dynamical properties of simulated or observed time series at various spatial scales. At continental scale, we compare GPP time series simulated with two models and an observations-based product. This analysis reveals qualitative differences between model evaluation based on ITQ compared to traditional model performance metrics, indicating that good model performance in terms of absolute or relative error does not imply that the dynamics of the observations is captured well. Furthermore, we show, using an ensemble of site-scale measurements obtained from the FLUXNET archive in the Mediterranean, that model-data or model-model mismatches as indicated by ITQ can be attributed to and interpreted as differences in the temporal structure of the respective ecological

  8. Diagnosing the Dynamics of Observed and Simulated Ecosystem Gross Primary Productivity with Time Causal Information Theory Quantifiers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sippel, Sebastian; Lange, Holger; Mahecha, Miguel D.

    Data analysis and model-data comparisons in the environmental sciences require diagnostic measures that quantify time series dynamics and structure, and are robust to noise in observational data. This paper investigates the temporal dynamics of environmental time series using measures quantifying their information content and complexity. The measures are used to classify natural processes on one hand, and to compare models with observations on the other. The present analysis focuses on the global carbon cycle as an area of research in which model-data integration and comparisons are key to improving our understanding of natural phenomena. We investigate the dynamics of observedmore » and simulated time series of Gross Primary Productivity (GPP), a key variable in terrestrial ecosystems that quantifies ecosystem carbon uptake. However, the dynamics, patterns and magnitudes of GPP time series, both observed and simulated, vary substantially on different temporal and spatial scales. Here we demonstrate that information content and complexity, or Information Theory Quantifiers (ITQ) for short, serve as robust and efficient data-analytical and model benchmarking tools for evaluating the temporal structure and dynamical properties of simulated or observed time series at various spatial scales. At continental scale, we compare GPP time series simulated with two models and an observations-based product. This analysis reveals qualitative differences between model evaluation based on ITQ compared to traditional model performance metrics, indicating that good model performance in terms of absolute or relative error does not imply that the dynamics of the observations is captured well. Furthermore, we show, using an ensemble of site-scale measurements obtained from the FLUXNET archive in the Mediterranean, that model-data or model-model mismatches as indicated by ITQ can be attributed to and interpreted as differences in the temporal structure of the respective ecological

  9. Diagnosing the Dynamics of Observed and Simulated Ecosystem Gross Primary Productivity with Time Causal Information Theory Quantifiers

    PubMed Central

    Sippel, Sebastian; Mahecha, Miguel D.; Hauhs, Michael; Bodesheim, Paul; Kaminski, Thomas; Gans, Fabian; Rosso, Osvaldo A.

    2016-01-01

    Data analysis and model-data comparisons in the environmental sciences require diagnostic measures that quantify time series dynamics and structure, and are robust to noise in observational data. This paper investigates the temporal dynamics of environmental time series using measures quantifying their information content and complexity. The measures are used to classify natural processes on one hand, and to compare models with observations on the other. The present analysis focuses on the global carbon cycle as an area of research in which model-data integration and comparisons are key to improving our understanding of natural phenomena. We investigate the dynamics of observed and simulated time series of Gross Primary Productivity (GPP), a key variable in terrestrial ecosystems that quantifies ecosystem carbon uptake. However, the dynamics, patterns and magnitudes of GPP time series, both observed and simulated, vary substantially on different temporal and spatial scales. We demonstrate here that information content and complexity, or Information Theory Quantifiers (ITQ) for short, serve as robust and efficient data-analytical and model benchmarking tools for evaluating the temporal structure and dynamical properties of simulated or observed time series at various spatial scales. At continental scale, we compare GPP time series simulated with two models and an observations-based product. This analysis reveals qualitative differences between model evaluation based on ITQ compared to traditional model performance metrics, indicating that good model performance in terms of absolute or relative error does not imply that the dynamics of the observations is captured well. Furthermore, we show, using an ensemble of site-scale measurements obtained from the FLUXNET archive in the Mediterranean, that model-data or model-model mismatches as indicated by ITQ can be attributed to and interpreted as differences in the temporal structure of the respective ecological time

  10. Quantifying electron transfer reactions in biological systems: what interactions play the major role?

    NASA Astrophysics Data System (ADS)

    Sjulstok, Emil; Olsen, Jógvan Magnus Haugaard; Solov'Yov, Ilia A.

    2015-12-01

    Various biological processes involve the conversion of energy into forms that are usable for chemical transformations and are quantum mechanical in nature. Such processes involve light absorption, excited electronic states formation, excitation energy transfer, electrons and protons tunnelling which for example occur in photosynthesis, cellular respiration, DNA repair, and possibly magnetic field sensing. Quantum biology uses computation to model biological interactions in light of quantum mechanical effects and has primarily developed over the past decade as a result of convergence between quantum physics and biology. In this paper we consider electron transfer in biological processes, from a theoretical view-point; namely in terms of quantum mechanical and semi-classical models. We systematically characterize the interactions between the moving electron and its biological environment to deduce the driving force for the electron transfer reaction and to establish those interactions that play the major role in propelling the electron. The suggested approach is seen as a general recipe to treat electron transfer events in biological systems computationally, and we utilize it to describe specifically the electron transfer reactions in Arabidopsis thaliana cryptochrome-a signaling photoreceptor protein that became attractive recently due to its possible function as a biological magnetoreceptor.

  11. Thermodynamic aspects of information transfer in complex dynamical systems

    NASA Astrophysics Data System (ADS)

    Cafaro, Carlo; Ali, Sean Alan; Giffin, Adom

    2016-02-01

    From the Horowitz-Esposito stochastic thermodynamical description of information flows in dynamical systems [J. M. Horowitz and M. Esposito, Phys. Rev. X 4, 031015 (2014), 10.1103/PhysRevX.4.031015], it is known that while the second law of thermodynamics is satisfied by a joint system, the entropic balance for the subsystems is adjusted by a term related to the mutual information exchange rate between the two subsystems. In this article, we present a quantitative discussion of the conceptual link between the Horowitz-Esposito analysis and the Liang-Kleeman work on information transfer between dynamical system components [X. S. Liang and R. Kleeman, Phys. Rev. Lett. 95, 244101 (2005), 10.1103/PhysRevLett.95.244101]. In particular, the entropic balance arguments employed in the two approaches are compared. Notwithstanding all differences between the two formalisms, our work strengthens the Liang-Kleeman heuristic balance reasoning by showing its formal analogy with the recent Horowitz-Esposito thermodynamic balance arguments.

  12. Genetic Redundancies Enhance Information Transfer in Noisy Regulatory Circuits

    PubMed Central

    Rodrigo, Guillermo; Poyatos, Juan F.

    2016-01-01

    Cellular decision making is based on regulatory circuits that associate signal thresholds to specific physiological actions. This transmission of information is subjected to molecular noise what can decrease its fidelity. Here, we show instead how such intrinsic noise enhances information transfer in the presence of multiple circuit copies. The result is due to the contribution of noise to the generation of autonomous responses by each copy, which are altogether associated with a common decision. Moreover, factors that correlate the responses of the redundant units (extrinsic noise or regulatory cross-talk) contribute to reduce fidelity, while those that further uncouple them (heterogeneity within the copies) can lead to stronger information gain. Overall, our study emphasizes how the interplay of signal thresholding, redundancy, and noise influences the accuracy of cellular decision making. Understanding this interplay provides a basis to explain collective cell signaling mechanisms, and to engineer robust decisions with noisy genetic circuits. PMID:27741249

  13. Phase Difference between Model Cortical Areas Determines Level of Information Transfer

    PubMed Central

    ter Wal, Marije; Tiesinga, Paul H.

    2017-01-01

    Communication between cortical sites is mediated by long-range synaptic connections. However, these connections are relatively static, while everyday cognitive tasks demand a fast and flexible routing of information in the brain. Synchronization of activity between distant cortical sites has been proposed as the mechanism underlying such a dynamic communication structure. Here, we study how oscillatory activity affects the excitability and input-output relation of local cortical circuits and how it alters the transmission of information between cortical circuits. To this end, we develop model circuits showing fast oscillations by the PING mechanism, of which the oscillatory characteristics can be altered. We identify conditions for synchronization between two brain circuits and show that the level of intercircuit coherence and the phase difference is set by the frequency difference between the intrinsic oscillations. We show that the susceptibility of the circuits to inputs, i.e., the degree of change in circuit output following input pulses, is not uniform throughout the oscillation period and that both firing rate, frequency and power are differentially modulated by inputs arriving at different phases. As a result, an appropriate phase difference between the circuits is critical for the susceptibility windows of the circuits in the network to align and for information to be efficiently transferred. We demonstrate that changes in synchrony and phase difference can be used to set up or abolish information transfer in a network of cortical circuits. PMID:28232796

  14. Report of a Planning Conference for Solar Technology Information Transfer in Georgia (Atlanta, Georgia, July 24-25, 1978).

    ERIC Educational Resources Information Center

    Aldridge, Mark C., Ed.

    A summary of the deliberations of the Georgia planning conference of the Solar Technology Transfer Program is presented in this report. Topic areas include background information on the Georgia conference and a summary of the discussions and recommendations dealing with solar information transfer within state systems and the need for greater…

  15. Administrative Aspects of Third World Library Development: The Five "Pillars" of Sustainable Information Transfer.

    ERIC Educational Resources Information Center

    Emerson, Susan Vince; And Others

    Third World libraries, as a rule, receive information technology, technical assistance, and training as part of international development projects. Library improvements and their intended objective, information transfer, are more effective and lasting if key administrative and policy issues are addressed by the projects. Critical success factors…

  16. Information transfer satellite concept study. Volume 1: Summary

    NASA Technical Reports Server (NTRS)

    Bergin, P.; Kincade, C.; Kurpiewski, D.; Leinhaupel, F.; Millican, F.; Onstad, R.

    1971-01-01

    A wide range of information transfer demands were identified and analyzed. They were then combined into an appropriate set of requirements for satellite communication services. In this process the demands were ranked and combined into single and multipurpose satellite systems. A detailed analysis was performed on each satellite system to determine: total system cost, including both ground and space segments; sensitivities of the systems to various system tradeoffs; and forcing functions which control the system variations. A listing of candidate missions for detailed study is presented, along with a description of the conceptual system design and an identification of the technology developments required to bring these systems to fruition.

  17. Estimating Temporal Causal Interaction between Spike Trains with Permutation and Transfer Entropy

    PubMed Central

    Li, Zhaohui; Li, Xiaoli

    2013-01-01

    Estimating the causal interaction between neurons is very important for better understanding the functional connectivity in neuronal networks. We propose a method called normalized permutation transfer entropy (NPTE) to evaluate the temporal causal interaction between spike trains, which quantifies the fraction of ordinal information in a neuron that has presented in another one. The performance of this method is evaluated with the spike trains generated by an Izhikevich’s neuronal model. Results show that the NPTE method can effectively estimate the causal interaction between two neurons without influence of data length. Considering both the precision of time delay estimated and the robustness of information flow estimated against neuronal firing rate, the NPTE method is superior to other information theoretic method including normalized transfer entropy, symbolic transfer entropy and permutation conditional mutual information. To test the performance of NPTE on analyzing simulated biophysically realistic synapses, an Izhikevich’s cortical network that based on the neuronal model is employed. It is found that the NPTE method is able to characterize mutual interactions and identify spurious causality in a network of three neurons exactly. We conclude that the proposed method can obtain more reliable comparison of interactions between different pairs of neurons and is a promising tool to uncover more details on the neural coding. PMID:23940662

  18. Improving Escalation of Care: Development and Validation of the Quality of Information Transfer Tool.

    PubMed

    Johnston, Maximilian J; Arora, Sonal; Pucher, Philip H; Reissis, Yannis; Hull, Louise; Huddy, Jeremy R; King, Dominic; Darzi, Ara

    2016-03-01

    To develop and provide validity and feasibility evidence for the QUality of Information Transfer (QUIT) tool. Prompt escalation of care in the setting of patient deterioration can prevent further harm. Escalation and information transfer skills are not currently measured in surgery. This study comprised 3 phases: the development (phase 1), validation (phase 2), and feasibility analysis (phase 3) of the QUIT tool. Phase 1 involved identification of core skills needed for successful escalation of care through literature review and 33 semistructured interviews with stakeholders. Phase 2 involved the generation of validity evidence for the tool using a simulated setting. Thirty surgeons assessed a deteriorating postoperative patient in a simulated ward and escalated their care to a senior colleague. The face and content validity were assessed using a survey. Construct and concurrent validity of the tool were determined by comparing performance scores using the QUIT tool with those measured using the Situation-Background-Assessment-Recommendation (SBAR) tool. Phase 3 was conducted using direct observation of escalation scenarios on surgical wards in 2 hospitals. A 7-category assessment tool was developed from phase 1 consisting of 24 items. Twenty-one of 24 items had excellent content validity (content validity index >0.8). All 7 categories and 18 of 24 (P < 0.05) items demonstrated construct validity. The correlation between the QUIT and SBAR tools used was strong indicating concurrent validity (r = 0.694, P < 0.001). Real-time scoring of escalation referrals was feasible and indicated that doctors currently have better information transfer skills than nurses when faced with a deteriorating patient. A validated tool to assess information transfer for deteriorating surgical patients was developed and tested using simulation and real-time clinical scenarios. It may improve the quality and safety of patient care on the surgical ward.

  19. A viscous solvent enables information transfer from gene-length nucleic acids in a model prebiotic replication cycle

    NASA Astrophysics Data System (ADS)

    He, Christine; Gállego, Isaac; Laughlin, Brandon; Grover, Martha A.; Hud, Nicholas V.

    2017-04-01

    Many hypotheses concerning the nature of early life assume that genetic information was once transferred through the template-directed synthesis of RNA, before the emergence of coded enzymes. However, attempts to demonstrate enzyme-free, template-directed synthesis of nucleic acids have been limited by 'strand inhibition', whereby transferring information from a template strand in the presence of its complementary strand is inhibited by the stability of the template duplex. Here, we use solvent viscosity to circumvent strand inhibition, demonstrating information transfer from a gene-length template (>300 nt) within a longer (545 bp or 3 kb) duplex. These results suggest that viscous environments on the prebiotic Earth, generated periodically by water evaporation, could have facilitated nucleic acid replication—particularly of long, structured sequences such as ribozymes. Our approach works with DNA and RNA, suggesting that viscosity-mediated replication is possible for a range of genetic polymers, perhaps even for informational polymers that may have preceded RNA.

  20. Hospital to Post-Acute Care Facility Transfers: Identifying Targets for Information Exchange Quality Improvement.

    PubMed

    Jones, Christine D; Cumbler, Ethan; Honigman, Benjamin; Burke, Robert E; Boxer, Rebecca S; Levy, Cari; Coleman, Eric A; Wald, Heidi L

    2017-01-01

    Information exchange is critical to high-quality care transitions from hospitals to post-acute care (PAC) facilities. We conducted a survey to evaluate the completeness and timeliness of information transfer and communication between a tertiary-care academic hospital and its related PAC facilities. This was a cross-sectional Web-based 36-question survey of 110 PAC clinicians and staff representing 31 PAC facilities conducted between October and December 2013. We received responses from 71 of 110 individuals representing 29 of 31 facilities (65% and 94% response rates). We collapsed 4-point Likert responses into dichotomous variables to reflect completeness (sufficient vs insufficient) and timeliness (timely vs not timely) for information transfer and communication. Among respondents, 32% reported insufficient information about discharge medical conditions and management plan, and 83% reported at least occasionally encountering problems directly related to inadequate information from the hospital. Hospital clinician contact information was the most common insufficient domain. With respect to timeliness, 86% of respondents desired receipt of a discharge summary on or before the day of discharge, but only 58% reported receiving the summary within this time frame. Through free-text responses, several participants expressed the need for paper prescriptions for controlled pain medications to be sent with patients at the time of transfer. Staff and clinicians at PAC facilities perceive substantial deficits in content and timeliness of information exchange between the hospital and facilities. Such deficits are particularly relevant in the context of the increasing prevalence of bundled payments for care across settings as well as forthcoming readmissions penalties for PAC facilities. Targets identified for quality improvement include structuring discharge summary information to include information identified as deficient by respondents, completion of discharge summaries

  1. Energy transfer, pressure tensor, and heating of kinetic plasma

    NASA Astrophysics Data System (ADS)

    Yang, Yan; Matthaeus, William H.; Parashar, Tulasi N.; Haggerty, Colby C.; Roytershteyn, Vadim; Daughton, William; Wan, Minping; Shi, Yipeng; Chen, Shiyi

    2017-07-01

    Kinetic plasma turbulence cascade spans multiple scales ranging from macroscopic fluid flow to sub-electron scales. Mechanisms that dissipate large scale energy, terminate the inertial range cascade, and convert kinetic energy into heat are hotly debated. Here, we revisit these puzzles using fully kinetic simulation. By performing scale-dependent spatial filtering on the Vlasov equation, we extract information at prescribed scales and introduce several energy transfer functions. This approach allows highly inhomogeneous energy cascade to be quantified as it proceeds down to kinetic scales. The pressure work, - ( P . ∇ ) . u , can trigger a channel of the energy conversion between fluid flow and random motions, which contains a collision-free generalization of the viscous dissipation in collisional fluid. Both the energy transfer and the pressure work are strongly correlated with velocity gradients.

  2. 76 FR 2758 - Agency Information Collection (Evidence for Transfer of Entitlement of Education Benefits (CFR 21...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-14

    ... for Transfer of Entitlement of Education Benefits (CFR 21.7080)) Activity Under OMB Review AGENCY... INFORMATION: Title: Evidence for Transfer of Entitlement of Education Benefits (CFR 21.7080). OMB Control... DOD Form 2366-1 to determine whether the dependent qualifies to receive education benefits under the...

  3. Energy and Information Transfer Via Coherent Exciton Wave Packets

    NASA Astrophysics Data System (ADS)

    Zang, Xiaoning

    associated excitations were dubbed twisted excitons. Twisted exciton packets can be manipulated as they travel down molecular chains, and this has applications in quantum information science as well. In each setting considered, exciton dynamics were initially studied using a simple tight-binding formalism. This misses the actual many-body interactions and multiple energy levels associated real systems. To remedy this, I adapted an existing time-domain Density Functional Theory code and applied it to study the dynamics of exciton wave packets on quasi-one-dimensional systems. This required the use of high-performance computing and the construction of a number of key auxiliary codes. Establishing the requisite methodology constituted a substantial part of the entire thesis. Surprisingly, this effort uncovered a computational issue associated with Rabi oscillations that had been incorrectly characterized in the literature. My research elucidated the actual problem and a solution was found. This new methodology was an integral part of the overall computational analysis. The thesis then takes up the a detailed consideration of the prospect for creating systems that support a strong measure of transport coherence. While physical implementations include molecular assemblies, solid-state superlattices, and even optical lattices, I decided to focus on assemblies of nanometer-sized silicon quantum dots. First principles computational analysis was used to quantify reorganization within individual dots and excitonic coupling between dots. Quantum dot functionalizations were identified that make it plausible to maintain a measure of excitonic coherence even at room temperatures. Attention was then turned to the use of covalently bonded bridge material to join quantum dots in a way that facilitates efficient exciton transfer. Both carbon and silicon structures were considered by considering the way in which subunits might be best brought together. This resulted in a set of design criteria

  4. Information filtering based on transferring similarity.

    PubMed

    Sun, Duo; Zhou, Tao; Liu, Jian-Guo; Liu, Run-Ran; Jia, Chun-Xiao; Wang, Bing-Hong

    2009-07-01

    In this Brief Report, we propose an index of user similarity, namely, the transferring similarity, which involves all high-order similarities between users. Accordingly, we design a modified collaborative filtering algorithm, which provides remarkably higher accurate predictions than the standard collaborative filtering. More interestingly, we find that the algorithmic performance will approach its optimal value when the parameter, contained in the definition of transferring similarity, gets close to its critical value, before which the series expansion of transferring similarity is convergent and after which it is divergent. Our study is complementary to the one reported in [E. A. Leicht, P. Holme, and M. E. J. Newman, Phys. Rev. E 73, 026120 (2006)], and is relevant to the missing link prediction problem.

  5. Transfer component skill deficit rates among Veterans who use wheelchairs.

    PubMed

    Koontz, Alicia M; Tsai, Chung-Ying; Hogaboom, Nathan S; Boninger, Michael L

    2016-01-01

    The purpose of this study was to quantify the deficit rates for transfer component skills in a Veteran cohort and explore the relationship between deficit rates and subject characteristics. Seventy-four men and 18 women performed up to four transfers independently from their wheelchair to a mat table while a therapist evaluated their transfer techniques using the Transfer Assessment Instrument. The highest deficit rates concerned the improper use of handgrips (63%). Other common problems included not setting the wheelchair up at the proper angle (50%) and not removing the armrest (58%). Veterans over 60 yr old and Veterans with moderate shoulder pain were more likely to set up their wheelchairs inappropriately than younger Veterans (p = 0.003) and Veterans with mild shoulder pain (p = 0.004). Women were less likely to remove their armrests than men (p = 0.03). Subjects with disabilities other than spinal cord injury were less inclined to set themselves up for a safe and easy transfer than the subjects with spinal cord injury (p ≤ 0.001). The results provide insight into the disparities present in transfer skills among Veterans and will inform the development of future transfer training programs both within and outside of the Department of Veterans Affairs.

  6. Analysis to Quantify Significant Contribution

    EPA Pesticide Factsheets

    This Technical Support Document provides information that supports EPA’s analysis to quantify upwind state emissions that significantly contribute to nonattainment or interfere with maintenance of National Ambient Air Quality Standards in downwind states.

  7. Information Transfer Problems of the Partially Sighted: Recent Results and Project Summary.

    ERIC Educational Resources Information Center

    Genensky, S. M.; And Others

    The fourth in a series of Rand reports on information transfer problems of the partially sighted reviews earlier reports and describes an experimental secretarial closed circuit TV (CCTV) system which enables the partially sighted to type from a printed or handwritten manuscript. Discussed are experiments using a pseudocolor system to determine…

  8. The information retrieval system of {open_quotes}heat abd nass transfer{close_quotes} software complexes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tsitsin, A.G.

    A project is discussed which is aimed at creating the International Center for certification of software complexes (SC), intended to for soling various heat and mass transfer problems. Information on the experience gained in the operation of an information retrieval SC system is presented.

  9. Counterfactual quantum-information transfer without transmitting any physical particles

    NASA Astrophysics Data System (ADS)

    Guo, Qi; Cheng, Liu-Yong; Chen, Li; Wang, Hong-Fu; Zhang, Shou

    2015-02-01

    We demonstrate quantum information can be transferred between two distant participants without any physical particles traveling between them. The key procedure of the counterfactual scheme is to entangle two nonlocal qubits with each other without interaction, so the scheme can also be used to generate nonlocal entanglement counterfactually. We here illustrate the scheme by using flying photon qubits and Rydberg atom qubits assisted by a mesoscopic atomic ensemble. Unlike the typical teleportation, the present scheme can transport an unknown qubit in a nondeterministic manner without prior entanglement sharing or classical communication between the two distant participants.

  10. Counterfactual quantum-information transfer without transmitting any physical particles.

    PubMed

    Guo, Qi; Cheng, Liu-Yong; Chen, Li; Wang, Hong-Fu; Zhang, Shou

    2015-02-12

    We demonstrate quantum information can be transferred between two distant participants without any physical particles traveling between them. The key procedure of the counterfactual scheme is to entangle two nonlocal qubits with each other without interaction, so the scheme can also be used to generate nonlocal entanglement counterfactually. We here illustrate the scheme by using flying photon qubits and Rydberg atom qubits assisted by a mesoscopic atomic ensemble. Unlike the typical teleportation, the present scheme can transport an unknown qubit in a nondeterministic manner without prior entanglement sharing or classical communication between the two distant participants.

  11. Information transfer rate with serial and simultaneous visual display formats

    NASA Astrophysics Data System (ADS)

    Matin, Ethel; Boff, Kenneth R.

    1988-04-01

    Information communication rate for a conventional display with three spatially separated windows was compared with rate for a serial display in which data frames were presented sequentially in one window. For both methods, each frame contained a randomly selected digit with various amounts of additional display 'clutter.' Subjects recalled the digits in a prescribed order. Large rate differences were found, with faster serial communication for all levels of the clutter factors. However, the rate difference was most pronounced for highly cluttered displays. An explanation for the latter effect in terms of visual masking in the retinal periphery was supported by the results of a second experiment. The working hypothesis that serial displays can speed information transfer for automatic but not for controlled processing is discussed.

  12. Safety of Rural Nursing Home-to-Emergency Department Transfers: Improving Communication and Patient Information Sharing Across Settings.

    PubMed

    Tupper, Judith B; Gray, Carolyn E; Pearson, Karen B; Coburn, Andrew F

    2015-01-01

    The "siloed" approach to healthcare delivery contributes to communication challenges and to potential patient harm when patients transfer between settings. This article reports on the evaluation of a demonstration in 10 rural communities to improve the safety of nursing facility (NF) transfers to hospital emergency departments by forming interprofessional teams of hospital, emergency medical service, and NF staff to develop and implement tools and protocols for standardizing critical interfacility communication pathways and information sharing. We worked with each of the 10 teams to document current communication processes and information sharing tools and to design, implement, and evaluate strategies/tools to increase effective communication and sharing of patient information across settings. A mixed methods approach was used to evaluate changes from baseline in documentation of patient information shared across settings during the transfer process. Study findings showed significant improvement in key areas across the three settings, including infection status and baseline mental functioning. Improvement strategies and performance varied across settings; however, accurate and consistent information sharing of advance directives and medication lists remains a challenge. Study results demonstrate that with neutral facilitation and technical support, collaborative interfacility teams can assess and effectively address communication and information sharing problems that threaten patient safety.

  13. The potential role of sea spray droplets in facilitating air-sea gas transfer

    NASA Astrophysics Data System (ADS)

    Andreas, E. L.; Vlahos, P.; Monahan, E. C.

    2016-05-01

    For over 30 years, air-sea interaction specialists have been evaluating and parameterizing the role of whitecap bubbles in air-sea gas exchange. To our knowledge, no one, however, has studied the mirror image process of whether sea spray droplets can facilitate air-sea gas exchange. We are therefore using theory, data analysis, and numerical modeling to quantify the role of spray on air-sea gas transfer. In this, our first formal work on this subject, we seek the rate-limiting step in spray-mediated gas transfer by evaluating the three time scales that govern the exchange: τ air , which quantifies the rate of transfer between the atmospheric gas reservoir and the surface of the droplet; τ int , which quantifies the exchange rate across the air-droplet interface; and τ aq , which quantifies gas mixing within the aqueous solution droplet.

  14. 26 CFR 1.6045A-1 - Statements of information required in connection with transfers of securities.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... stock, how that stock is held, and how many shares each investor owns. O transfers the stock to D. (ii... statement that includes the information described in paragraph (b) of this section with respect to the transferred security. Except as provided in paragraphs (b)(1)(vii) and (b)(3) of this section (relating to...

  15. 26 CFR 1.6045A-1 - Statements of information required in connection with transfers of securities.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... stock, how that stock is held, and how many shares each investor owns. O transfers the stock to D. (ii... statement that includes the information described in paragraph (b) of this section with respect to the transferred security. Except as provided in paragraphs (b)(1)(vii) and (b)(3) of this section (relating to...

  16. 26 CFR 1.6045A-1 - Statements of information required in connection with transfers of securities.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... stock, how that stock is held, and how many shares each investor owns. O transfers the stock to D. (ii... statement that includes the information described in paragraph (b) of this section with respect to the transferred security. Except as provided in paragraphs (b)(1)(vii) and (b)(3) of this section (relating to...

  17. 26 CFR 1.6045A-1 - Statements of information required in connection with transfers of securities.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... stock, how that stock is held, and how many shares each investor owns. O transfers the stock to D. (ii... statement that includes the information described in paragraph (b) of this section with respect to the transferred security. Except as provided in paragraphs (b)(1)(vii) and (b)(3) of this section (relating to...

  18. Multiscale analysis of information dynamics for linear multivariate processes.

    PubMed

    Faes, Luca; Montalto, Alessandro; Stramaglia, Sebastiano; Nollo, Giandomenico; Marinazzo, Daniele

    2016-08-01

    In the study of complex physical and physiological systems represented by multivariate time series, an issue of great interest is the description of the system dynamics over a range of different temporal scales. While information-theoretic approaches to the multiscale analysis of complex dynamics are being increasingly used, the theoretical properties of the applied measures are poorly understood. This study introduces for the first time a framework for the analytical computation of information dynamics for linear multivariate stochastic processes explored at different time scales. After showing that the multiscale processing of a vector autoregressive (VAR) process introduces a moving average (MA) component, we describe how to represent the resulting VARMA process using statespace (SS) models and how to exploit the SS model parameters to compute analytical measures of information storage and information transfer for the original and rescaled processes. The framework is then used to quantify multiscale information dynamics for simulated unidirectionally and bidirectionally coupled VAR processes, showing that rescaling may lead to insightful patterns of information storage and transfer but also to potentially misleading behaviors.

  19. A Method to Quantify Visual Information Processing in Children Using Eye Tracking

    PubMed Central

    Kooiker, Marlou J.G.; Pel, Johan J.M.; van der Steen-Kant, Sanny P.; van der Steen, Johannes

    2016-01-01

    Visual problems that occur early in life can have major impact on a child's development. Without verbal communication and only based on observational methods, it is difficult to make a quantitative assessment of a child's visual problems. This limits accurate diagnostics in children under the age of 4 years and in children with intellectual disabilities. Here we describe a quantitative method that overcomes these problems. The method uses a remote eye tracker and a four choice preferential looking paradigm to measure eye movement responses to different visual stimuli. The child sits without head support in front of a monitor with integrated infrared cameras. In one of four monitor quadrants a visual stimulus is presented. Each stimulus has a specific visual modality with respect to the background, e.g., form, motion, contrast or color. From the reflexive eye movement responses to these specific visual modalities, output parameters such as reaction times, fixation accuracy and fixation duration are calculated to quantify a child's viewing behavior. With this approach, the quality of visual information processing can be assessed without the use of communication. By comparing results with reference values obtained in typically developing children from 0-12 years, the method provides a characterization of visual information processing in visually impaired children. The quantitative information provided by this method can be advantageous for the field of clinical visual assessment and rehabilitation in multiple ways. The parameter values provide a good basis to: (i) characterize early visual capacities and consequently to enable early interventions; (ii) compare risk groups and follow visual development over time; and (iii), construct an individual visual profile for each child. PMID:27500922

  20. A Method to Quantify Visual Information Processing in Children Using Eye Tracking.

    PubMed

    Kooiker, Marlou J G; Pel, Johan J M; van der Steen-Kant, Sanny P; van der Steen, Johannes

    2016-07-09

    Visual problems that occur early in life can have major impact on a child's development. Without verbal communication and only based on observational methods, it is difficult to make a quantitative assessment of a child's visual problems. This limits accurate diagnostics in children under the age of 4 years and in children with intellectual disabilities. Here we describe a quantitative method that overcomes these problems. The method uses a remote eye tracker and a four choice preferential looking paradigm to measure eye movement responses to different visual stimuli. The child sits without head support in front of a monitor with integrated infrared cameras. In one of four monitor quadrants a visual stimulus is presented. Each stimulus has a specific visual modality with respect to the background, e.g., form, motion, contrast or color. From the reflexive eye movement responses to these specific visual modalities, output parameters such as reaction times, fixation accuracy and fixation duration are calculated to quantify a child's viewing behavior. With this approach, the quality of visual information processing can be assessed without the use of communication. By comparing results with reference values obtained in typically developing children from 0-12 years, the method provides a characterization of visual information processing in visually impaired children. The quantitative information provided by this method can be advantageous for the field of clinical visual assessment and rehabilitation in multiple ways. The parameter values provide a good basis to: (i) characterize early visual capacities and consequently to enable early interventions; (ii) compare risk groups and follow visual development over time; and (iii), construct an individual visual profile for each child.

  1. Methods, systems, and apparatus for storage, transfer and/or control of information via matter wave dynamics

    NASA Technical Reports Server (NTRS)

    Vestergaard Hau, Lene (Inventor)

    2012-01-01

    Methods, systems and apparatus for generating atomic traps, and for storing, controlling and transferring information between first and second spatially separated phase-coherent objects, or using a single phase-coherent object. For plural objects, both phase-coherent objects have a macroscopic occupation of a particular quantum state by identical bosons or identical BCS-paired fermions. The information may be optical information, and the phase-coherent object(s) may be Bose-Einstein condensates, superfluids, or superconductors. The information is stored in the first phase-coherent object at a first storage time and recovered from the second phase-coherent object, or the same first phase-coherent object, at a second revival time. In one example, an integrated silicon wafer-based optical buffer includes an electrolytic atom source to provide the phase-coherent object(s), a nanoscale atomic trap for the phase-coherent object(s), and semiconductor-based optical sources to cool the phase-coherent object(s) and provide coupling fields for storage and transfer of optical information.

  2. Staff perceptions of best practice for information transfer about multitrauma patients on discharge from the emergency department: a focus group study.

    PubMed

    Calleja, Pauline; Aitken, Leanne; Cooke, Marie

    2016-10-01

    To understand: (1) staff perceptions of best practice for information transfer for multitrauma patients on discharge from the emergency department; (2) what information should be conveyed at transfer and (3) how information is transferred. Information transfer for multitrauma patients is an integral factor for continuity of care, safety, quality assurance and patient outcomes; however, this has not been the focus of previous studies. This was a qualitative study using focus group interviews. Data were collected during focus group interviews across five clinical areas. Themes were derived from the data with consensus from three data coders. Purposive sampling was used and included staff caring for trauma patients during patient transition out of the emergency department. Participants were representatives of the emergency department, perioperative care, intensive care unit, high dependency care unit and the trauma service unit. Twenty-six registered nurses and two medical officers participated. Five focus group interviews were held. Themes emerged from the data including 'Variability', 'Continuity' and 'Putting the pieces together'. The first three themes were all influenced by the fourth theme of 'Values/Context'. Considered together these themes influenced staff perception of the quality of information transfer for multitrauma patients on discharge from the emergency department. Staff perceived best practice for information transfer to be clear, concise, relevant documentation that travelled with the patient and interactive communication at handover that adhered to agreed principles and a minimum data set specific to trauma patients. Clinicians involved in handover need to actively listen, avoiding 'doing' at the same time, be aware of essential questions to ask about the patient. An agreed expectation between different clinical areas needs to exist about information transfer to reduce variability. The minimum data required to provide ongoing safe care for

  3. Is nitrogen transfer among plants enhanced by contrasting nutrient-acquisition strategies?

    PubMed

    Teste, François P; Veneklaas, Erik J; Dixon, Kingsley W; Lambers, Hans

    2015-01-01

    Nitrogen (N) transfer among plants has been found where at least one plant can fix N2 . In nutrient-poor soils, where plants with contrasting nutrient-acquisition strategies (without N2 fixation) co-occur, it is unclear if N transfer exists and what promotes it. A novel multi-species microcosm pot experiment was conducted to quantify N transfer between arbuscular mycorrhizal (AM), ectomycorrhizal (EM), dual AM/EM, and non-mycorrhizal cluster-rooted plants in nutrient-poor soils with mycorrhizal mesh barriers. We foliar-fed plants with a K(15) NO3 solution to quantify one-way N transfer from 'donor' to 'receiver' plants. We also quantified mycorrhizal colonization and root intermingling. Transfer of N between plants with contrasting nutrient-acquisition strategies occurred at both low and high soil nutrient levels with or without root intermingling. The magnitude of N transfer was relatively high (representing 4% of donor plant N) given the lack of N2 fixation. Receiver plants forming ectomycorrhizas or cluster roots were more enriched compared with AM-only plants. We demonstrate N transfer between plants of contrasting nutrient-acquisition strategies, and a preferential enrichment of cluster-rooted and EM plants compared with AM plants. Nutrient exchanges among plants are potentially important in promoting plant coexistence in nutrient-poor soils. © 2014 John Wiley & Sons Ltd.

  4. Controls, Displays, and Information Transfer for General Aviation IFR Operations

    NASA Technical Reports Server (NTRS)

    Bergeron, H. P. (Editor); Shaughnessy, J. D. (Editor)

    1983-01-01

    The purpose of the workshop was to review and evaluate the work performed under the NASA Single Pilot IFR (SPIFR) program, to highlight and disseminate major research findings, and to provide a forum for industry, universities, and government to interact and discuss the future thrust of research in the SPIFR program. The presentations selected represent key elements of the SPIFR program. These elements are classified into five disciplinary areas: program definition, controls, displays, information transfer, and research simulation facilities. Emphasis is also placed on aircraft accident investigation.

  5. An internet-based communication network for information transfer during patient transitions from skilled nursing facility to the emergency department.

    PubMed

    Hustey, Fredric M; Palmer, Robert M

    2010-06-01

    To determine whether the implementation of an Internet-based communication system improves the amount of essential information conveyed between a skilled nursing facility (SNF) and the emergency department (ED) during patient care transitions. Interventional; before and after. ED of an urban teaching hospital with approximately 55,000 visits per year and a 55-bed subacute free-standing rehabilitation facility (the SNF). All patients transferred from the SNF to the ED over 16 months. An Internet-based communication network with SNF-ED transfer form for communication during patient care transitions. Nine elements of patient information assessed before and after intervention through chart review. changes in efficiency of information transfer and staff satisfaction. Two hundred thirty-four of 237 preintervention and all 276 postintervention care transitions were reviewed. The Internet communication network was used in 78 (26%) of all care transitions, peaking at 40% by the end of the study. There was more critical patient information (1.85 vs 4.29 of 9 elements; P<.001) contained within fewer pages of transfer documents (24.47 vs 5.15; P<.001) after the intervention. Staff satisfaction with communication was higher among ED physicians after the intervention. The use of an Internet-based system increased the amount of information communicated during SNF-ED care transitions and significantly reduced the number of pages in which this information was contained.

  6. 77 FR 71035 - Financial Management Service; Proposed Collection of Information: Electronic Funds Transfer (EFT...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-28

    ... DEPARTMENT OF THE TREASURY Fiscal Service Financial Management Service; Proposed Collection of Information: Electronic Funds Transfer (EFT) Market Research Study AGENCY: Financial Management Service, Fiscal Service, Treasury. ACTION: Notice and Request for comments. SUMMARY: The Financial Management...

  7. A REVIEW OF EFFORTS TO ORGANIZE INFORMATION ABOUT HUMAN LEARNING, TRANSFER, AND RETENTION.

    ERIC Educational Resources Information Center

    GINSBERG, ROSE; AND OTHERS

    FOURTEEN EFFORTS TO ORGANIZE AVAILABLE INFORMATION ON HUMAN LEARNING, TRANSFER, AND RETENTION ARE SUMMARIZED AND EVALUATED ON SIX CRITERIA--BEHAVIORAL SIGNIFICANCE OF CATEGORIES, SCOPE, OBJECTIVITY AND RELIABILITY OF CATEGORIES, PROGNOSIS FOR THE SYSTEM, LOGICAL STRUCTURE, AND HEURISTIC VALUE OF THE SYSTEM. ATTENTION IS GIVEN TO OTHER SOURCES OF…

  8. Information transfer and synchronization among the scales of climate variability: clues for understanding anomalies and extreme events?

    NASA Astrophysics Data System (ADS)

    Palus, Milan

    2017-04-01

    Deeper understanding of complex dynamics of the Earth atmosphere and climate is inevitable for sustainable development, mitigation and adaptation strategies for global change and for prediction of and resilience against extreme events. Traditional (linear) approaches cannot explain or even detect nonlinear interactions of dynamical processes evolving on multiple spatial and temporal scales. Combination of nonlinear dynamics and information theory explains synchronization as a process of adjustment of information rates [1] and causal relations (à la Granger) as information transfer [2]. Information born in dynamical complexity or information transferred among systems on a way to synchronization might appear as an abstract quantity, however, information transfer is tied to a transfer of mass and energy, as demonstrated in a recent study using directed (causal) climate networks [2]. Recently, an information transfer across scales of atmospheric dynamics has been observed [3]. In particular, a climate oscillation with the period around 7-8 years has been identified as a factor influencing variability of surface air temperature (SAT) on shorter time scales. Its influence on the amplitude of the SAT annual cycle was estimated in the range 0.7-1.4 °C and the effect on the overall variability of the SAT anomalies (SATA) leads to the changes 1.5-1.7 °C in the annual SATA means. The strongest effect of the 7-8 year cycle was observed in the winter SATA means where it reaches 4-5 °C in central European station and reanalysis data [4]. In the dynamics of El Niño-Southern Oscillation, three principal time scales have been identified: the annual cycle (AC), the quasibiennial (QB) mode(s) and the low-frequency (LF) variability. An intricate causal network of information flows among these modes helps to understand the occurrence of extreme El Niño events, characterized by synchronization of the QB modes and AC, and modulation of the QB amplitude by the LF mode. The latter

  9. Somatic cell nuclear transfer in Oregon: expanding the pluripotent space and informing research ethics.

    PubMed

    Lomax, Geoffrey P; DeWitt, Natalie D

    2013-12-01

    In May, Oregon Health and Science University (OHSU) announced the successful derivation, by the Mitalipov laboratory, of embryonic stem cells by somatic cell nuclear transfer. This experiment was recognized as a "formidable technical feat" and potentially a key step toward developing cell-based therapies. The OHSU report is also an example of how a scientific breakthrough can inform research ethics. This article suggests ways that nuclear transfer embryonic stem cell lines may contribute to research ethics by adding rigor to studies addressing pressing research questions important to the development of cell-based therapies.

  10. Human machine interaction via the transfer of power and information signals

    NASA Technical Reports Server (NTRS)

    Kazerooni, H.; Foslien, W. K.; Anderson, B. J.; Hessburg, T. M.

    1989-01-01

    Robot manipulators are designed to perform tasks which would otherwise be executed by a human operator. No manipulator can even approach the speed and accuracy with which humans execute these tasks. But manipulators have the capability to exceed human ability in one particular area: strength. Through any reasonable observation and experience, the human's ability to perform a variety of physical tasks is limited not by his intelligence, but by his physical strength. If, in the appropriate environment, we can more closely integrate the mechanical power of a machine with intellectually driven human hand under the supervisory control of the human's intellect, we will then have a system which is superior to a loosely-integrated combination of a human and his fully automated robot as in the present day robotic systems. We must therefore develop a fundamental approach to the problem of this extending human mechanical power in certain environments. Extenders will be a class of robots worn by humans to increase human mechanical ability, while the wearer's intellect remains the central intelligent control system for manipulating the extender. The human body, in physical contact with the extender, exchanges information signals and power with the extender. Commands are transferred to the extender via the contact forces between the wearer and the extender as opposed to use of joystick (master arm), push-button or key-board to execute such commands that were used in previous man amplifiers. Instead, the operator becomes an integral part of the extender while executing the task. In this unique configuration the mechanical power transfer between the human and extender occurs in addition to information signal transfer. When the wearer uses the extender to touch and manipulate an object, the extender transfers to the wearer's hand, in feedback fashion, a scaled-down value of the actual external load which the extender is manipulating. This natural feedback force on the wearer's hand

  11. Method and apparatus for detecting and quantifying bacterial spores on a surface

    NASA Technical Reports Server (NTRS)

    Ponce, Adrian (Inventor)

    2009-01-01

    A method and an apparatus for detecting and quantifying bacterial spores on a surface. In accordance with the method: bacterial spores are transferred from a place of origin to a test surface, the test surface comprises lanthanide ions. Aromatic molecules are released from the bacterial spores; a complex of the lanthanide ions and aromatic molecules is formed on the test surface, the complex is excited to generate a characteristic luminescence on the test surface; the luminescence on the test surface is detected and quantified.

  12. Method and Apparatus for Detecting and Quantifying Bacterial Spores on a Surface

    NASA Technical Reports Server (NTRS)

    Ponce, Adrian (Inventor)

    2016-01-01

    A method and an apparatus for detecting and quantifying bacterial spores on a surface. In accordance with the method: bacterial spores are transferred from a place of origin to a test surface, the test surface comprises lanthanide ions. Aromatic molecules are released from the bacterial spores; a complex of the lanthanide ions and aromatic molecules is formed on the test surface, the complex is excited to generate a characteristic luminescence on the test surface; the luminescence on the test surface is detected and quantified.

  13. Conditions for Lorentz-invariant superluminal information transfer without signaling

    NASA Astrophysics Data System (ADS)

    Grössing, G.; Fussy, S.; Mesa Pascasio, J.; Schwabl, H.

    2016-03-01

    We understand emergent quantum mechanics in the sense that quantum mechanics describes processes of physical emergence relating an assumed sub-quantum physics to macroscopic boundary conditions. The latter can be shown to entail top-down causation, in addition to usual bottom-up scenarios. With this example it is demonstrated that definitions of “realism” in the literature are simply too restrictive. A prevailing manner to define realism in quantum mechanics is in terms of pre-determination independent of the measurement. With our counter-example, which actually is ubiquitous in emergent, or self-organizing, systems, we argue for realism without pre-determination. We refer to earlier results of our group showing how the guiding equation of the de Broglie-Bohm interpretation can be derived from a theory with classical ingredients only. Essentially, this corresponds to a “quantum mechanics without wave functions” in ordinary 3-space, albeit with nonlocal correlations. This, then, leads to the central question of how to deal with the nonlocality problem in a relativistic setting. We here show that a basic argument discussing the allegedly paradox time ordering of events in EPR-type two-particle experiments falls short of taking into account the contextuality of the experimental setup. Consequently, we then discuss under which circumstances (i.e. physical premises) superluminal information transfer (but not signaling) may be compatible with a Lorentz-invariant theory. Finally, we argue that the impossibility of superluminal signaling - despite the presence of superluminal information transfer - is not the result of some sort of conspiracy (á la “Nature likes to hide”), but the consequence of the impossibility to exactly reproduce in repeated experimental runs a state's preparation, or of the no-cloning theorem, respectively.

  14. Blood perfusion construction for infrared face recognition based on bio-heat transfer.

    PubMed

    Xie, Zhihua; Liu, Guodong

    2014-01-01

    To improve the performance of infrared face recognition for time-lapse data, a new construction of blood perfusion is proposed based on bio-heat transfer. Firstly, by quantifying the blood perfusion based on Pennes equation, the thermal information is converted into blood perfusion rate, which is stable facial biological feature of face image. Then, the separability discriminant criterion in Discrete Cosine Transform (DCT) domain is applied to extract the discriminative features of blood perfusion information. Experimental results demonstrate that the features of blood perfusion are more concentrative and discriminative for recognition than those of thermal information. The infrared face recognition based on the proposed blood perfusion is robust and can achieve better recognition performance compared with other state-of-the-art approaches.

  15. Effects of Initial Correlation and Quantum Coherence on the Energy Transfer, Purity and Entanglement

    NASA Astrophysics Data System (ADS)

    Meng, Xiangjia; Chen, Longxi

    2018-04-01

    We investigate the influences of the initial correlation and quantum coherence on a bipartite dissipative system which is modeled by two two-level quantum emitters driven by an external laser field. It is shown that the initial correlation can enhance or suppress the dynamical evolution of the energy transfer quantified by the excited-state population and the information flow between the two emitters characterized by the purity. We also present the degree of the influence of the initial correlation that is determined by the quantum coherence induced by a relative phase. By introducing Bloch sphere, we illustrate the relation between the energy transfer and the purity. In addition, a scheme for generating maximally entangled steady state is proposed.

  16. Report of a Planning Conference for Solar Technology Information Transfer. Jackson, Mississippi, September 7-8, 1978.

    ERIC Educational Resources Information Center

    Graves, Sid F., Jr., Ed.

    This summary of the decisions and recommendations of the Planning Conference for Solar Technology Information Transfer includes a brief discussion of the outline of a functioning solar energy technology network in the State of Mississippi. During the conference, participants recognized current energy information needs and recommended ways to meet…

  17. Quantifying the Value of Downscaled Climate Model Information for Adaptation Decisions: When is Downscaling a Smart Decision?

    NASA Astrophysics Data System (ADS)

    Terando, A. J.; Wootten, A.; Eaton, M. J.; Runge, M. C.; Littell, J. S.; Bryan, A. M.; Carter, S. L.

    2015-12-01

    Two types of decisions face society with respect to anthropogenic climate change: (1) whether to enact a global greenhouse gas abatement policy, and (2) how to adapt to the local consequences of current and future climatic changes. The practice of downscaling global climate models (GCMs) is often used to address (2) because GCMs do not resolve key features that will mediate global climate change at the local scale. In response, the development of downscaling techniques and models has accelerated to aid decision makers seeking adaptation guidance. However, quantifiable estimates of the value of information are difficult to obtain, particularly in decision contexts characterized by deep uncertainty and low system-controllability. Here we demonstrate a method to quantify the additional value that decision makers could expect if research investments are directed towards developing new downscaled climate projections. As a proof of concept we focus on a real-world management problem: whether to undertake assisted migration for an endangered tropical avian species. We also take advantage of recently published multivariate methods that account for three vexing issues in climate impacts modeling: maximizing climate model quality information, accounting for model dependence in ensembles of opportunity, and deriving probabilistic projections. We expand on these global methods by including regional (Caribbean Basin) and local (Puerto Rico) domains. In the local domain, we test whether a high resolution (2km) dynamically downscaled GCM reduces the multivariate error estimate compared to the original coarse-scale GCM. Initial tests show little difference between the downscaled and original GCM multivariate error. When propagated through to a species population model, the Value of Information analysis indicates that the expected utility that would accrue to the manager (and species) if this downscaling were completed may not justify the cost compared to alternative actions.

  18. Public service communications satellite. [health, education, safety and information transfer applications

    NASA Technical Reports Server (NTRS)

    Wolff, E. A.

    1978-01-01

    Health, education, public safety, and information transfer applications of public service communications satellites are discussed with particular attention to the use of communications satellites to improve rural health delivery. Health-care communications requirements are summarized. The communications system concept involves small inexpensive stationary, portable, and moving ground terminals which will provide communications between any two points in the U.S. with both fixed and moving terminals on a continuous 24-hour basis. User requirements, wavebands, and privacy techniques are surveyed.

  19. The origin and dynamic evolution of chemical information transfer

    PubMed Central

    Steiger, Sandra; Schmitt, Thomas; Schaefer, H. Martin

    2011-01-01

    Although chemical communication is the most widespread form of communication, its evolution and diversity are not well understood. By integrating studies of a wide range of terrestrial plants and animals, we show that many chemicals are emitted, which can unintentionally provide information (cues) and, therefore, act as direct precursors for the evolution of intentional communication (signals). Depending on the content, design and the original function of the cue, there are predictable ways that selection can enhance the communicative function of chemicals. We review recent progress on how efficacy-based selection by receivers leads to distinct evolutionary trajectories of chemical communication. Because the original function of a cue may channel but also constrain the evolution of functional communication, we show that a broad perspective on multiple selective pressures acting upon chemicals provides important insights into the origin and dynamic evolution of chemical information transfer. Finally, we argue that integrating chemical ecology into communication theory may significantly enhance our understanding of the evolution, the design and the content of signals in general. PMID:21177681

  20. Efficient transfer of information from hexitol nucleic acids to RNA during nonenzymatic oligomerization

    NASA Technical Reports Server (NTRS)

    Kozlov, I. A.; De Bouvere, B.; Van Aerschot, A.; Herdewijn, P.; Orgel, L. E.

    1999-01-01

    Hexitol nucleic acids (HNAs) are DNA analogues that contain the standard nucleoside bases attached to a phosphorylated 1,5-anhydrohexitol backbone. We find that HNAs support efficient information transfer in nonensymatic template-directed reactions. HNA heterosequences appeared to be superior to the corresponding DNA heterosequences in facilitating synthesis of complementary oligonucleotides from nucleoside-5'-phosphoro-2-methyl imidazolides.

  1. Dynamic information routing in complex networks

    PubMed Central

    Kirst, Christoph; Timme, Marc; Battaglia, Demian

    2016-01-01

    Flexible information routing fundamentally underlies the function of many biological and artificial networks. Yet, how such systems may specifically communicate and dynamically route information is not well understood. Here we identify a generic mechanism to route information on top of collective dynamical reference states in complex networks. Switching between collective dynamics induces flexible reorganization of information sharing and routing patterns, as quantified by delayed mutual information and transfer entropy measures between activities of a network's units. We demonstrate the power of this mechanism specifically for oscillatory dynamics and analyse how individual unit properties, the network topology and external inputs co-act to systematically organize information routing. For multi-scale, modular architectures, we resolve routing patterns at all levels. Interestingly, local interventions within one sub-network may remotely determine nonlocal network-wide communication. These results help understanding and designing information routing patterns across systems where collective dynamics co-occurs with a communication function. PMID:27067257

  2. Instantaneous Transfer Entropy for the Study of Cardiovascular and Cardiorespiratory Nonstationary Dynamics.

    PubMed

    Valenza, Gaetano; Faes, Luca; Citi, Luca; Orini, Michele; Barbieri, Riccardo

    2018-05-01

    Measures of transfer entropy (TE) quantify the direction and strength of coupling between two complex systems. Standard approaches assume stationarity of the observations, and therefore are unable to track time-varying changes in nonlinear information transfer with high temporal resolution. In this study, we aim to define and validate novel instantaneous measures of TE to provide an improved assessment of complex nonstationary cardiorespiratory interactions. We here propose a novel instantaneous point-process TE (ipTE) and validate its assessment as applied to cardiovascular and cardiorespiratory dynamics. In particular, heartbeat and respiratory dynamics are characterized through discrete time series, and modeled with probability density functions predicting the time of the next physiological event as a function of the past history. Likewise, nonstationary interactions between heartbeat and blood pressure dynamics are characterized as well. Furthermore, we propose a new measure of information transfer, the instantaneous point-process information transfer (ipInfTr), which is directly derived from point-process-based definitions of the Kolmogorov-Smirnov distance. Analysis on synthetic data, as well as on experimental data gathered from healthy subjects undergoing postural changes confirms that ipTE, as well as ipInfTr measures are able to dynamically track changes in physiological systems coupling. This novel approach opens new avenues in the study of hidden, transient, nonstationary physiological states involving multivariate autonomic dynamics in cardiovascular health and disease. The proposed method can also be tailored for the study of complex multisystem physiology (e.g., brain-heart or, more in general, brain-body interactions).

  3. Quantifying Network Dynamics and Information Flow Across Chinese Social Media During the African Ebola Outbreak.

    PubMed

    Feng, Shihui; Hossain, Liaquat; Crawford, John W; Bossomaier, Terry

    2018-02-01

    Social media provides us with a new platform on which to explore how the public responds to disasters and, of particular importance, how they respond to the emergence of infectious diseases such as Ebola. Provided it is appropriately informed, social media offers a potentially powerful means of supporting both early detection and effective containment of communicable diseases, which is essential for improving disaster medicine and public health preparedness. The 2014 West African Ebola outbreak is a particularly relevant contemporary case study on account of the large number of annual arrivals from Africa, including Chinese employees engaged in projects in Africa. Weibo (Weibo Corp, Beijing, China) is China's most popular social media platform, with more than 2 billion users and over 300 million daily posts, and offers great opportunity to monitor early detection and promotion of public health awareness. We present a proof-of-concept study of a subset of Weibo posts during the outbreak demonstrating potential and identifying priorities for improving the efficacy and accuracy of information dissemination. We quantify the evolution of the social network topology within Weibo relating to the efficacy of information sharing. We show how relatively few nodes in the network can have a dominant influence over both the quality and quantity of the information shared. These findings make an important contribution to disaster medicine and public health preparedness from theoretical and methodological perspectives for dealing with epidemics. (Disaster Med Public Health Preparedness. 2018;12:26-37).

  4. Clinical information transfer and data capture in the acute myocardial infarction pathway: an observational study.

    PubMed

    Kesavan, Sujatha; Kelay, Tanika; Collins, Ruth E; Cox, Benita; Bello, Fernando; Kneebone, Roger L; Sevdalis, Nick

    2013-10-01

    Acute myocardial infarctions (MIs) or heart attacks are the result of a complete or an incomplete occlusion of the lumen of the coronary artery with a thrombus. Prompt diagnosis and early coronary intervention results in maximum myocardial salvage, hence time to treat is of the essence. Adequate, accurate and complete information is vital during the early stages of admission of an MI patient and can impact significantly on the quality and safety of patient care. This study aimed to record how clinical information between different clinical teams during the journey of a patient in the MI care pathway is captured and to review the flow of information within this care pathway. A prospective, descriptive, structured observational study to assess (i) current clinical information systems (CIS) utilization and (ii) real-time information availability within an acute cardiac care setting was carried out. Completeness and availability of patient information capture across four key stages of the MI care pathway were assessed prospectively. Thirteen separate information systems were utilized during the four phases of the MI pathway. Observations revealed fragmented CIS utilization, with users accessing an average of six systems to gain a complete set of patient information. Data capture was found to vary between each pathway stage and in both patient cohort risk groupings. The highest level of information completeness (100%) was observed only in the discharge stage of the MI care pathway. The lowest level of information completeness (58%) was observed in the admission stage. The study highlights fragmentation, CIS duplication, and discrepancies in the current clinical information capture and data transfer across the MI care pathway in an acute cardiac care setting. The development of an integrated and user-friendly electronic data capture and transfer system would reduce duplication and would facilitate efficient and complete information provision at the point of care. © 2012

  5. British Columbia Transfer Guide, 2002-2003: The Official Guide to Post-Secondary Credit Transfer in B.C.

    ERIC Educational Resources Information Center

    British Columbia Council on Admissions and Transfer, Vancouver.

    This transfer 2002-2003 transfer guide for the province of British Columbia offers detailed information for college transfer students. The guide documents provincial transfer policy and process, as well as offering specific transfer information for some institutions. It is suggested that it be used in conjunction with the Online Transfer Guide and…

  6. Measurement of Transference Interpretations

    PubMed Central

    Bøgwald, Kjell-Petter; Høglend, Per; Sørbye, Øystein

    1999-01-01

    The authors present a cost-efficient process rating scale for detailed measurement of how much transference interpretations and related therapist interventions are used in brief dynamic psychotherapy. Theoretical and methodological considerations on how to operationalize and quantify such therapeutic interventions are discussed. The scale had highly satisfactory interrater reliability for three raters, who rated 60 whole sessions from an ongoing randomized study of two manualized forms of brief dynamic psychotherapy. In one treatment group, moderate emphasis on transference analysis was intended. In the other, minor or no use of the studied component was intended. The two treatment groups differed significantly in the use of transference interpretations and related interventions. There was no significant difference in therapists' general therapeutic skill or use of supportive interventions. The treatment differentiation was consistent with the manuals. PMID:10523429

  7. Spontaneous trait inference and spontaneous trait transference are both unaffected by prior evaluations of informants.

    PubMed

    Zengel, Bettina; Ambler, James K; McCarthy, Randy J; Skowronski, John J

    2017-01-01

    This article reports results from a study in which participants encountered either (a) previously known informants who were positive (e.g. Abraham Lincoln), neutral (e.g., Jay Leno), or negative (e.g., Adolf Hitler), or (b) previously unknown informants. The informants ostensibly described either a trait-implicative positive behavior, a trait-implicative negative behavior, or a neutral behavior. These descriptions were framed as either the behavior of the informant or the behavior of another person. Results yielded evidence of informant-trait linkages for both self-informants and for informants who described another person. These effects were not moderated by informant type, behavior valence, or the congruency or incongruency between the prior knowledge of the informant and the behavior valence. Results are discussed in terms of theories of Spontaneous Trait Inference and Spontaneous Trait Transference.

  8. The study on knowledge transferring incentive for information system requirement development

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, Yang

    2015-03-10

    Information system requirement development is a process of users’ knowledge sharing and transferring. However the tacit requirements developing is a main problem during requirement development process, for the reason of difficult to encoding, express, and communicate. Knowledge fusion and corporate effort is needed to finding tacit requirements. Under this background, our paper try to find out the rule of effort dynamic evolutionary of software developer and user by building an evolutionary game model on the condition of incentive system. And in addition this paper provides an in depth discussion at the end of this paper.

  9. Quantifying Parameter Sensitivity, Interaction and Transferability in Hydrologically Enhanced Versions of Noah-LSM over Transition Zones

    NASA Technical Reports Server (NTRS)

    Rosero, Enrique; Yang, Zong-Liang; Wagener, Thorsten; Gulden, Lindsey E.; Yatheendradas, Soni; Niu, Guo-Yue

    2009-01-01

    We use sensitivity analysis to identify the parameters that are most responsible for shaping land surface model (LSM) simulations and to understand the complex interactions in three versions of the Noah LSM: the standard version (STD), a version enhanced with a simple groundwater module (GW), and version augmented by a dynamic phenology module (DV). We use warm season, high-frequency, near-surface states and turbulent fluxes collected over nine sites in the US Southern Great Plains. We quantify changes in the pattern of sensitive parameters, the amount and nature of the interaction between parameters, and the covariance structure of the distribution of behavioral parameter sets. Using Sobol s total and first-order sensitivity indexes, we show that very few parameters directly control the variance of the model output. Significant parameter interaction occurs so that not only the optimal parameter values differ between models, but the relationships between parameters change. GW decreases parameter interaction and appears to improve model realism, especially at wetter sites. DV increases parameter interaction and decreases identifiability, implying it is overparameterized and/or underconstrained. A case study at a wet site shows GW has two functional modes: one that mimics STD and a second in which GW improves model function by decoupling direct evaporation and baseflow. Unsupervised classification of the posterior distributions of behavioral parameter sets cannot group similar sites based solely on soil or vegetation type, helping to explain why transferability between sites and models is not straightforward. This evidence suggests a priori assignment of parameters should also consider climatic differences.

  10. Quantifying and reducing model-form uncertainties in Reynolds-averaged Navier–Stokes simulations: A data-driven, physics-informed Bayesian approach

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Xiao, H., E-mail: hengxiao@vt.edu; Wu, J.-L.; Wang, J.-X.

    Despite their well-known limitations, Reynolds-Averaged Navier–Stokes (RANS) models are still the workhorse tools for turbulent flow simulations in today's engineering analysis, design and optimization. While the predictive capability of RANS models depends on many factors, for many practical flows the turbulence models are by far the largest source of uncertainty. As RANS models are used in the design and safety evaluation of many mission-critical systems such as airplanes and nuclear power plants, quantifying their model-form uncertainties has significant implications in enabling risk-informed decision-making. In this work we develop a data-driven, physics-informed Bayesian framework for quantifying model-form uncertainties in RANS simulations.more » Uncertainties are introduced directly to the Reynolds stresses and are represented with compact parameterization accounting for empirical prior knowledge and physical constraints (e.g., realizability, smoothness, and symmetry). An iterative ensemble Kalman method is used to assimilate the prior knowledge and observation data in a Bayesian framework, and to propagate them to posterior distributions of velocities and other Quantities of Interest (QoIs). We use two representative cases, the flow over periodic hills and the flow in a square duct, to evaluate the performance of the proposed framework. Both cases are challenging for standard RANS turbulence models. Simulation results suggest that, even with very sparse observations, the obtained posterior mean velocities and other QoIs have significantly better agreement with the benchmark data compared to the baseline results. At most locations the posterior distribution adequately captures the true model error within the developed model form uncertainty bounds. The framework is a major improvement over existing black-box, physics-neutral methods for model-form uncertainty quantification, where prior knowledge and details of the models are not exploited. This approach

  11. Quantifying Neural Oscillatory Synchronization: A Comparison between Spectral Coherence and Phase-Locking Value Approaches

    PubMed Central

    Lowet, Eric; Roberts, Mark J.; Bonizzi, Pietro; Karel, Joël; De Weerd, Peter

    2016-01-01

    Synchronization or phase-locking between oscillating neuronal groups is considered to be important for coordination of information among cortical networks. Spectral coherence is a commonly used approach to quantify phase locking between neural signals. We systematically explored the validity of spectral coherence measures for quantifying synchronization among neural oscillators. To that aim, we simulated coupled oscillatory signals that exhibited synchronization dynamics using an abstract phase-oscillator model as well as interacting gamma-generating spiking neural networks. We found that, within a large parameter range, the spectral coherence measure deviated substantially from the expected phase-locking. Moreover, spectral coherence did not converge to the expected value with increasing signal-to-noise ratio. We found that spectral coherence particularly failed when oscillators were in the partially (intermittent) synchronized state, which we expect to be the most likely state for neural synchronization. The failure was due to the fast frequency and amplitude changes induced by synchronization forces. We then investigated whether spectral coherence reflected the information flow among networks measured by transfer entropy (TE) of spike trains. We found that spectral coherence failed to robustly reflect changes in synchrony-mediated information flow between neural networks in many instances. As an alternative approach we explored a phase-locking value (PLV) method based on the reconstruction of the instantaneous phase. As one approach for reconstructing instantaneous phase, we used the Hilbert Transform (HT) preceded by Singular Spectrum Decomposition (SSD) of the signal. PLV estimates have broad applicability as they do not rely on stationarity, and, unlike spectral coherence, they enable more accurate estimations of oscillatory synchronization across a wide range of different synchronization regimes, and better tracking of synchronization-mediated information

  12. Shifts of Gamma Phase across Primary Visual Cortical Sites Reflect Dynamic Stimulus-Modulated Information Transfer.

    PubMed

    Besserve, Michel; Lowe, Scott C; Logothetis, Nikos K; Schölkopf, Bernhard; Panzeri, Stefano

    2015-01-01

    Distributed neural processing likely entails the capability of networks to reconfigure dynamically the directionality and strength of their functional connections. Yet, the neural mechanisms that may allow such dynamic routing of the information flow are not yet fully understood. We investigated the role of gamma band (50-80 Hz) oscillations in transient modulations of communication among neural populations by using measures of direction-specific causal information transfer. We found that the local phase of gamma-band rhythmic activity exerted a stimulus-modulated and spatially-asymmetric directed effect on the firing rate of spatially separated populations within the primary visual cortex. The relationships between gamma phases at different sites (phase shifts) could be described as a stimulus-modulated gamma-band wave propagating along the spatial directions with the largest information transfer. We observed transient stimulus-related changes in the spatial configuration of phases (compatible with changes in direction of gamma wave propagation) accompanied by a relative increase of the amount of information flowing along the instantaneous direction of the gamma wave. These effects were specific to the gamma-band and suggest that the time-varying relationships between gamma phases at different locations mark, and possibly causally mediate, the dynamic reconfiguration of functional connections.

  13. Shifts of Gamma Phase across Primary Visual Cortical Sites Reflect Dynamic Stimulus-Modulated Information Transfer

    PubMed Central

    Besserve, Michel; Lowe, Scott C.; Logothetis, Nikos K.; Schölkopf, Bernhard; Panzeri, Stefano

    2015-01-01

    Distributed neural processing likely entails the capability of networks to reconfigure dynamically the directionality and strength of their functional connections. Yet, the neural mechanisms that may allow such dynamic routing of the information flow are not yet fully understood. We investigated the role of gamma band (50–80 Hz) oscillations in transient modulations of communication among neural populations by using measures of direction-specific causal information transfer. We found that the local phase of gamma-band rhythmic activity exerted a stimulus-modulated and spatially-asymmetric directed effect on the firing rate of spatially separated populations within the primary visual cortex. The relationships between gamma phases at different sites (phase shifts) could be described as a stimulus-modulated gamma-band wave propagating along the spatial directions with the largest information transfer. We observed transient stimulus-related changes in the spatial configuration of phases (compatible with changes in direction of gamma wave propagation) accompanied by a relative increase of the amount of information flowing along the instantaneous direction of the gamma wave. These effects were specific to the gamma-band and suggest that the time-varying relationships between gamma phases at different locations mark, and possibly causally mediate, the dynamic reconfiguration of functional connections. PMID:26394205

  14. 77 FR 22067 - Proposed Collection of Information: Trace Request for Electronic Funds Transfer (EFT) Payment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-12

    ... Electronic Funds Transfer (EFT) Payment; and Trace Request Direct Deposit AGENCY: Financial Management... collection. By this notice, the Financial Management Service solicits comments concerning forms FMS-150.1... comments to Financial Management Service, 3700 East West Highway, Records and Information Management Branch...

  15. Information transfer with rate-modulated Poisson processes: a simple model for nonstationary stochastic resonance.

    PubMed

    Goychuk, I

    2001-08-01

    Stochastic resonance in a simple model of information transfer is studied for sensory neurons and ensembles of ion channels. An exact expression for the information gain is obtained for the Poisson process with the signal-modulated spiking rate. This result allows one to generalize the conventional stochastic resonance (SR) problem (with periodic input signal) to the arbitrary signals of finite duration (nonstationary SR). Moreover, in the case of a periodic signal, the rate of information gain is compared with the conventional signal-to-noise ratio. The paper establishes the general nonequivalence between both measures notwithstanding their apparent similarity in the limit of weak signals.

  16. MuTE: a MATLAB toolbox to compare established and novel estimators of the multivariate transfer entropy.

    PubMed

    Montalto, Alessandro; Faes, Luca; Marinazzo, Daniele

    2014-01-01

    A challenge for physiologists and neuroscientists is to map information transfer between components of the systems that they study at different scales, in order to derive important knowledge on structure and function from the analysis of the recorded dynamics. The components of physiological networks often interact in a nonlinear way and through mechanisms which are in general not completely known. It is then safer that the method of choice for analyzing these interactions does not rely on any model or assumption on the nature of the data and their interactions. Transfer entropy has emerged as a powerful tool to quantify directed dynamical interactions. In this paper we compare different approaches to evaluate transfer entropy, some of them already proposed, some novel, and present their implementation in a freeware MATLAB toolbox. Applications to simulated and real data are presented.

  17. MuTE: A MATLAB Toolbox to Compare Established and Novel Estimators of the Multivariate Transfer Entropy

    PubMed Central

    Montalto, Alessandro; Faes, Luca; Marinazzo, Daniele

    2014-01-01

    A challenge for physiologists and neuroscientists is to map information transfer between components of the systems that they study at different scales, in order to derive important knowledge on structure and function from the analysis of the recorded dynamics. The components of physiological networks often interact in a nonlinear way and through mechanisms which are in general not completely known. It is then safer that the method of choice for analyzing these interactions does not rely on any model or assumption on the nature of the data and their interactions. Transfer entropy has emerged as a powerful tool to quantify directed dynamical interactions. In this paper we compare different approaches to evaluate transfer entropy, some of them already proposed, some novel, and present their implementation in a freeware MATLAB toolbox. Applications to simulated and real data are presented. PMID:25314003

  18. Revealing Relationships among Relevant Climate Variables with Information Theory

    NASA Technical Reports Server (NTRS)

    Knuth, Kevin H.; Golera, Anthony; Curry, Charles T.; Huyser, Karen A.; Kevin R. Wheeler; Rossow, William B.

    2005-01-01

    The primary objective of the NASA Earth-Sun Exploration Technology Office is to understand the observed Earth climate variability, thus enabling the determination and prediction of the climate's response to both natural and human-induced forcing. We are currently developing a suite of computational tools that will allow researchers to calculate, from data, a variety of information-theoretic quantities such as mutual information, which can be used to identify relationships among climate variables, and transfer entropy, which indicates the possibility of causal interactions. Our tools estimate these quantities along with their associated error bars, the latter of which is critical for describing the degree of uncertainty in the estimates. This work is based upon optimal binning techniques that we have developed for piecewise-constant, histogram-style models of the underlying density functions. Two useful side benefits have already been discovered. The first allows a researcher to determine whether there exist sufficient data to estimate the underlying probability density. The second permits one to determine an acceptable degree of round-off when compressing data for efficient transfer and storage. We also demonstrate how mutual information and transfer entropy can be applied so as to allow researchers not only to identify relations among climate variables, but also to characterize and quantify their possible causal interactions.

  19. Where do HIV-infected adolescents go after transfer? - Tracking transition/transfer of HIV-infected adolescents using linkage of cohort data to a health information system platform.

    PubMed

    Davies, Mary-Ann; Tsondai, Priscilla; Tiffin, Nicki; Eley, Brian; Rabie, Helena; Euvrard, Jonathan; Orrell, Catherine; Prozesky, Hans; Wood, Robin; Cogill, Dolphina; Haas, Andreas D; Sohn, Annette H; Boulle, Andrew

    2017-05-16

    successful transfer. Linking cohort data to health information system data allowed efficient assessment of post-transfer outcomes. Although >80% of adolescents transferred successfully with nearly 85% of them retained for 3 years post-transfer, the decline in the proportion virologically suppressed and poorer outcomes in older adolescents are concerns.​.

  20. Report of a Planning Conference for Solar Technology Information Transfer in Kentucky (Frankfort, September 11-12, 1978).

    ERIC Educational Resources Information Center

    Capps, Randall, Ed.

    This summary of the deliberations of the Planning Conference for Solar Technology Information Transfer includes an outline of a functioning solar energy technology network for the State of Kentucky and a set of recommendations for future action. Four main types of information agents were identified: (1) the State Library System; (2) the State…

  1. Information technology in complex health services: organizational impediments to successful technology transfer and diffusion.

    PubMed

    Southon, F C; Sauer, C; Grant, C N

    1997-01-01

    To identify impediments to the successful transfer and implementation of packaged information systems through large, divisionalized health services. A case analysis of the failure of an implementation of a critical application in the Public Health System of the State of New South Wales, Australia, was carried out. This application had been proven in the United States environment. Interviews involving over 60 staff at all levels of the service were undertaken by a team of three. The interviews were recorded and analyzed for key themes, and the results were shared and compared to enable a continuing critical assessment. Two components of the transfer of the system were considered: the transfer from a different environment, and the diffusion throughout a large, divisionalized organization. The analyses were based on the Scott-Morton organizational fit framework. In relation to the first, it was found that there was a lack of fit in the business environments and strategies, organizational structures and strategy-structure pairing as well as the management process-roles pairing. The diffusion process experienced problems because of the lack of fit in the strategy-structure, strategy-structure-management processes, and strategy-structure-role relationships. The large-scale developments of integrated health services present great challenges to the efficient and reliable implementation of information technology, especially in large, divisionalized organizations. There is a need to take a more sophisticated approach to understanding the complexities of organizational factors than has traditionally been the case.

  2. Helium Evolution from the Transfer of Helium Saturated Propellant in Space

    NASA Technical Reports Server (NTRS)

    Nguyen, Bich N.

    2000-01-01

    Helium evolution from the transfer of helium saturated propellant in space is quantified to determine its impact from creating a two-phase mixture in the transfer line. The transfer line is approximately 1/2 inch in diameter and 2400 inches in length comprised of the Fluid Interconnect System (FICS), the Orbiter Propellant Transfer System (OPTS) and the International Space Station (ISS) Propulsion Module (ISSPM). The propellant transfer rate is approximately two to three gallons per minute, and the supply tank pressure is maintained at approximately 250 psig.

  3. Info-disruption: pollution and the transfer of chemical information between organisms.

    PubMed

    Lürling, Miquel; Scheffer, Marten

    2007-07-01

    Many organisms use subtle chemical cues not only to find partners and food, but also to sense the presence of natural enemies and to avoid predation. As we discuss here, an increasing number of studies now show that low, non-toxic concentrations of chemicals, ranging from heavy metals and pesticides to seemingly harmless substances such as surfactants, can disrupt the transfer of chemical information, inducing maladaptive responses in both the signaller and the receiver. Similar to endocrine disruptors, these 'info disruptors' form a new class of chemical threats, which could have far-reaching implications for ecosystem functioning and conservation management.

  4. Quantifying the Role of Atmospheric Forcing in Ice Edge Retreat and Advance Including Wind-Wave Coupling

    DTIC Science & Technology

    2015-09-30

    Quantifying the Role of Atmospheric Forcing in Ice Edge Retreat and Advance Including Wind- Wave Coupling Peter S. Guest (NPS Technical Contact) Naval...surface fluxes and ocean waves in coupled models in the Beaufort and Chukchi Seas. 2. Understand the physics of heat and mass transfer from the ocean...to the atmosphere. 3. Improve forecasting of waves on the open ocean and in the marginal ice zone. 2 OBJECTIVES 1. Quantifying the open-ocean

  5. BioShuttle-mediated Plasmid Transfer

    PubMed Central

    Braun, Klaus; von Brasch, Leonie; Pipkorn, Ruediger; Ehemann, Volker; Jenne, Juergen; Spring, Herbert; Debus, Juergen; Didinger, Bernd; Rittgen, Werner; Waldeck, Waldemar

    2007-01-01

    An efficient gene transfer into target tissues and cells is needed for safe and effective treatment of genetic diseases like cancer. In this paper, we describe the development of a transport system and show its ability for transporting plasmids. This non-viral peptide-based BioShuttle-mediated transfer system consists of a nuclear localization address sequence realizing the delivery of the plasmid phNIS-IRES-EGFP coding for two independent reporter genes into nuclei of HeLa cells. The quantification of the transfer efficiency was achieved by measurements of the sodium iodide symporter activity. EGFP gene expression was measured with Confocal Laser Scanning Microscopy and quantified with biostatistical methods by analysis of the frequency of the amplitude distribution in the CLSM images. The results demonstrate that the “BioShuttle”-Technology is an appropriate tool for an effective transfer of genetic material carried by a plasmid. PMID:18026568

  6. Transfer research and impact studies program

    NASA Technical Reports Server (NTRS)

    Freeman, J. E. (Editor)

    1975-01-01

    Methods developed for stimulating interest in the transfer of NASA-originated technology are described. These include: new information packaging concepts; technology transfer via people transfer; information management systems; data bank operations; and professional communication activities.

  7. Quantifying non-Gaussianity for quantum information

    NASA Astrophysics Data System (ADS)

    Genoni, Marco G.; Paris, Matteo G. A.

    2010-11-01

    We address the quantification of non-Gaussianity (nG) of states and operations in continuous-variable systems and its use in quantum information. We start by illustrating in detail the properties and the relationships of two recently proposed measures of nG based on the Hilbert-Schmidt distance and the quantum relative entropy (QRE) between the state under examination and a reference Gaussian state. We then evaluate the non-Gaussianities of several families of non-Gaussian quantum states and show that the two measures have the same basic properties and also share the same qualitative behavior in most of the examples taken into account. However, we also show that they introduce a different relation of order; that is, they are not strictly monotone to each other. We exploit the nG measures for states in order to introduce a measure of nG for quantum operations, to assess Gaussification and de-Gaussification protocols, and to investigate in detail the role played by nG in entanglement-distillation protocols. Besides, we exploit the QRE-based nG measure to provide different insight on the extremality of Gaussian states for some entropic quantities such as conditional entropy, mutual information, and the Holevo bound. We also deal with parameter estimation and present a theorem connecting the QRE nG to the quantum Fisher information. Finally, since evaluation of the QRE nG measure requires the knowledge of the full density matrix, we derive some experimentally friendly lower bounds to nG for some classes of states and by considering the possibility of performing on the states only certain efficient or inefficient measurements.

  8. Cerebrovascular and cardiovascular variability interactions investigated through conditional joint transfer entropy in subjects prone to postural syncope.

    PubMed

    Bari, Vlasta; De Maria, Beatrice; Mazzucco, Claudio Enrico; Rossato, Gianluca; Tonon, Davide; Nollo, Giandomenico; Faes, Luca; Porta, Alberto

    2017-05-01

    A model-based conditional transfer entropy approach was exploited to quantify the information transfer in cerebrovascular (CBV) and cardiovascular (CV) systems in subjects prone to develop postural syncope. Spontaneous beat-to-beat variations of mean cerebral blood flow velocity (MCBFV) derived from a transcranial Doppler device, heart period (HP) derived from surface electrocardiogram, mean arterial pressure (MAP) and systolic arterial pressure (SAP) derived from finger plethysmographic arterial pressure device were monitored at rest in supine position (REST) and during 60° head-up tilt (TILT) in 13 individuals (age mean  ±  standard deviation: 28  ±  9 years, min-max range: 18-44 years, 5 males) with a history of recurrent episodes of syncope (SYNC) and in 13 age- and gender-matched controls (NonSYNC). Respiration (R) obtained from a thoracic belt was acquired as well and considered as a conditioning signal in transfer entropy assessment. Synchronous sequences of 250 consecutive MCBFV, HP, MAP, SAP and R values were utilized to estimate the information genuinely transferred from MAP to MCBFV (i.e. disambiguated from R influences) and vice versa. Analogous indexes were computed from SAP to HP and vice versa. Traditional time and frequency domain analyses were carried out as well. SYNC subjects showed an increased genuine information transfer from MAP to MCBFV during TILT, while they did not exhibit the expected rise of the genuine information transfer from SAP to HP. We conclude that SYNC individuals featured an impaired cerebral autoregulation visible during TILT and were unable to activate cardiac baroreflex to cope with the postural challenge. Traditional frequency domain markers based on transfer function modulus, phase and coherence functions were less powerful or less specific in typifying the CBV and CV controls of SYNC individuals. Conditional transfer entropy approach can identify the impairment of CBV and CV controls and provide

  9. Quantifying Environmental Effects on the Decay of Hole Transfer Couplings in Biosystems.

    PubMed

    Ramos, Pablo; Pavanello, Michele

    2014-06-10

    In the past two decades, many research groups worldwide have tried to understand and categorize simple regimes in the charge transfer of such biological systems as DNA. Theoretically speaking, the lack of exact theories for electron-nuclear dynamics on one side and poor quality of the parameters needed by model Hamiltonians and nonadiabatic dynamics alike (such as couplings and site energies) on the other are the two main difficulties for an appropriate description of the charge transfer phenomena. In this work, we present an application of a previously benchmarked and linear-scaling subsystem density functional theory (DFT) method for the calculation of couplings, site energies, and superexchange decay factors (β) of several biological donor-acceptor dyads, as well as double stranded DNA oligomers composed of up to five base pairs. The calculations are all-electron and provide a clear view of the role of the environment on superexchange couplings in DNA-they follow experimental trends and confirm previous semiempirical calculations. The subsystem DFT method is proven to be an excellent tool for long-range, bridge-mediated coupling and site energy calculations of embedded molecular systems.

  10. Quantifying cadherin mechanotransduction machinery assembly/disassembly dynamics using fluorescence covariance analysis.

    PubMed

    Vedula, Pavan; Cruz, Lissette A; Gutierrez, Natasha; Davis, Justin; Ayee, Brian; Abramczyk, Rachel; Rodriguez, Alexis J

    2016-06-30

    Quantifying multi-molecular complex assembly in specific cytoplasmic compartments is crucial to understand how cells use assembly/disassembly of these complexes to control function. Currently, biophysical methods like Fluorescence Resonance Energy Transfer and Fluorescence Correlation Spectroscopy provide quantitative measurements of direct protein-protein interactions, while traditional biochemical approaches such as sub-cellular fractionation and immunoprecipitation remain the main approaches used to study multi-protein complex assembly/disassembly dynamics. In this article, we validate and quantify multi-protein adherens junction complex assembly in situ using light microscopy and Fluorescence Covariance Analysis. Utilizing specific fluorescently-labeled protein pairs, we quantified various stages of adherens junction complex assembly, the multiprotein complex regulating epithelial tissue structure and function following de novo cell-cell contact. We demonstrate: minimal cadherin-catenin complex assembly in the perinuclear cytoplasm and subsequent localization to the cell-cell contact zone, assembly of adherens junction complexes, acto-myosin tension-mediated anchoring, and adherens junction maturation following de novo cell-cell contact. Finally applying Fluorescence Covariance Analysis in live cells expressing fluorescently tagged adherens junction complex proteins, we also quantified adherens junction complex assembly dynamics during epithelial monolayer formation.

  11. Image-Based Modeling of Blood Flow and Oxygen Transfer in Feto-Placental Capillaries

    PubMed Central

    Brownbill, Paul; Janáček, Jiří; Jirkovská, Marie; Kubínová, Lucie; Chernyavsky, Igor L.; Jensen, Oliver E.

    2016-01-01

    During pregnancy, oxygen diffuses from maternal to fetal blood through villous trees in the placenta. In this paper, we simulate blood flow and oxygen transfer in feto-placental capillaries by converting three-dimensional representations of villous and capillary surfaces, reconstructed from confocal laser scanning microscopy, to finite-element meshes, and calculating values of vascular flow resistance and total oxygen transfer. The relationship between the total oxygen transfer rate and the pressure drop through the capillary is shown to be captured across a wide range of pressure drops by physical scaling laws and an upper bound on the oxygen transfer rate. A regression equation is introduced that can be used to estimate the oxygen transfer in a capillary using the vascular resistance. Two techniques for quantifying the effects of statistical variability, experimental uncertainty and pathological placental structure on the calculated properties are then introduced. First, scaling arguments are used to quantify the sensitivity of the model to uncertainties in the geometry and the parameters. Second, the effects of localized dilations in fetal capillaries are investigated using an idealized axisymmetric model, to quantify the possible effect of pathological placental structure on oxygen transfer. The model predicts how, for a fixed pressure drop through a capillary, oxygen transfer is maximized by an optimal width of the dilation. The results could explain the prevalence of fetal hypoxia in cases of delayed villous maturation, a pathology characterized by a lack of the vasculo-syncytial membranes often seen in conjunction with localized capillary dilations. PMID:27788214

  12. Quantifying Information Flow During Emergencies

    NASA Astrophysics Data System (ADS)

    Gao, Liang; Song, Chaoming; Gao, Ziyou; Barabási, Albert-László; Bagrow, James P.; Wang, Dashun

    2014-02-01

    Recent advances on human dynamics have focused on the normal patterns of human activities, with the quantitative understanding of human behavior under extreme events remaining a crucial missing chapter. This has a wide array of potential applications, ranging from emergency response and detection to traffic control and management. Previous studies have shown that human communications are both temporally and spatially localized following the onset of emergencies, indicating that social propagation is a primary means to propagate situational awareness. We study real anomalous events using country-wide mobile phone data, finding that information flow during emergencies is dominated by repeated communications. We further demonstrate that the observed communication patterns cannot be explained by inherent reciprocity in social networks, and are universal across different demographics.

  13. Interlimb transfer of motor skill learning during walking: No evidence for asymmetric transfer.

    PubMed

    Krishnan, Chandramouli; Ranganathan, Rajiv; Tetarbe, Manik

    2017-07-01

    Several studies have shown that learning a motor skill in one limb can transfer to the opposite limb-a phenomenon called as interlimb transfer. The transfer of motor skills between limbs, however, has shown to be asymmetric, where one side benefits to a greater extent than the other. While this phenomenon has been well-documented in the upper-extremity, evidence for interlimb transfer in the lower-extremity is limited and mixed. This study investigated the extent of interlimb transfer during walking, and tested whether this transfer was asymmetric using a foot trajectory-tracking paradigm that has been specifically used for gait rehabilitation. The paradigm involved learning a new gait pattern which required greater hip and knee flexion during the swing phase of the gait while walking on a treadmill. Twenty young adults were randomized into two equal groups, where one group (right-to-left: RL) practiced the task initially with the dominant right leg and the other group (left-to-right: LR) practiced the task initially with their non-dominant left leg. After training, both groups practiced the task with their opposite leg to test the transfer effects. The changes in tracking error on each leg were computed to quantify learning and transfer effects. The results indicated that practice with one leg improved the motor performance of the other leg; however, the amount of transfer was similar across groups, indicating that there was no asymmetry in transfer. This finding is contradictory to most upper-extremity studies (where asymmetric transfer has been reported) and points out that both differences in neural processes and types of tasks may mediate interlimb transfer. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. Information transfer from peptide nucleic acids to RNA by template-directed syntheses

    NASA Technical Reports Server (NTRS)

    Schmidt, J. G.; Nielsen, P. E.; Orgel, L. E.; Bada, J. L. (Principal Investigator)

    1997-01-01

    Peptide nucleic acids (PNAs) are uncharged analogs of DNA and RNA in which the ribose-phosphate backbone is substituted by a backbone held together by amide bonds. PNAs are interesting as models of alternative genetic systems because they form potentially informational base paired helical structures. A PNA C10 oligomer has been shown to act as template for efficient formation of oligoguanylates from activated guanosine ribonucleotides. In a previous paper we used heterosequences of DNA as templates in sequence-dependent polymerization of PNA dimers. In this paper we show that information can be transferred from PNA to RNA. We describe the reactions of activated mononucleotides on heterosequences of PNA. Adenylic, cytidylic and guanylic acids were incorporated into the products opposite their complement on PNA, although less efficiently than on DNA templates.

  15. TRENTOOL: A Matlab open source toolbox to analyse information flow in time series data with transfer entropy

    PubMed Central

    2011-01-01

    Background Transfer entropy (TE) is a measure for the detection of directed interactions. Transfer entropy is an information theoretic implementation of Wiener's principle of observational causality. It offers an approach to the detection of neuronal interactions that is free of an explicit model of the interactions. Hence, it offers the power to analyze linear and nonlinear interactions alike. This allows for example the comprehensive analysis of directed interactions in neural networks at various levels of description. Here we present the open-source MATLAB toolbox TRENTOOL that allows the user to handle the considerable complexity of this measure and to validate the obtained results using non-parametrical statistical testing. We demonstrate the use of the toolbox and the performance of the algorithm on simulated data with nonlinear (quadratic) coupling and on local field potentials (LFP) recorded from the retina and the optic tectum of the turtle (Pseudemys scripta elegans) where a neuronal one-way connection is likely present. Results In simulated data TE detected information flow in the simulated direction reliably with false positives not exceeding the rates expected under the null hypothesis. In the LFP data we found directed interactions from the retina to the tectum, despite the complicated signal transformations between these stages. No false positive interactions in the reverse directions were detected. Conclusions TRENTOOL is an implementation of transfer entropy and mutual information analysis that aims to support the user in the application of this information theoretic measure. TRENTOOL is implemented as a MATLAB toolbox and available under an open source license (GPL v3). For the use with neural data TRENTOOL seamlessly integrates with the popular FieldTrip toolbox. PMID:22098775

  16. TRENTOOL: a Matlab open source toolbox to analyse information flow in time series data with transfer entropy.

    PubMed

    Lindner, Michael; Vicente, Raul; Priesemann, Viola; Wibral, Michael

    2011-11-18

    Transfer entropy (TE) is a measure for the detection of directed interactions. Transfer entropy is an information theoretic implementation of Wiener's principle of observational causality. It offers an approach to the detection of neuronal interactions that is free of an explicit model of the interactions. Hence, it offers the power to analyze linear and nonlinear interactions alike. This allows for example the comprehensive analysis of directed interactions in neural networks at various levels of description. Here we present the open-source MATLAB toolbox TRENTOOL that allows the user to handle the considerable complexity of this measure and to validate the obtained results using non-parametrical statistical testing. We demonstrate the use of the toolbox and the performance of the algorithm on simulated data with nonlinear (quadratic) coupling and on local field potentials (LFP) recorded from the retina and the optic tectum of the turtle (Pseudemys scripta elegans) where a neuronal one-way connection is likely present. In simulated data TE detected information flow in the simulated direction reliably with false positives not exceeding the rates expected under the null hypothesis. In the LFP data we found directed interactions from the retina to the tectum, despite the complicated signal transformations between these stages. No false positive interactions in the reverse directions were detected. TRENTOOL is an implementation of transfer entropy and mutual information analysis that aims to support the user in the application of this information theoretic measure. TRENTOOL is implemented as a MATLAB toolbox and available under an open source license (GPL v3). For the use with neural data TRENTOOL seamlessly integrates with the popular FieldTrip toolbox.

  17. The Role of Book Features in Young Children's Transfer of Information from Picture Books to Real-World Contexts

    PubMed Central

    Strouse, Gabrielle A.; Nyhout, Angela; Ganea, Patricia A.

    2018-01-01

    Picture books are an important source of new language, concepts, and lessons for young children. A large body of research has documented the nature of parent-child interactions during shared book reading. A new body of research has begun to investigate the features of picture books that support children's learning and transfer of that information to the real world. In this paper, we discuss how children's symbolic development, analogical reasoning, and reasoning about fantasy may constrain their ability to take away content information from picture books. We then review the nascent body of findings that has focused on the impact of picture book features on children's learning and transfer of words and letters, science concepts, problem solutions, and morals from picture books. In each domain of learning we discuss how children's development may interact with book features to impact their learning. We conclude that children's ability to learn and transfer content from picture books can be disrupted by some book features and research should directly examine the interaction between children's developing abilities and book characteristics on children's learning. PMID:29467690

  18. The Role of Book Features in Young Children's Transfer of Information from Picture Books to Real-World Contexts.

    PubMed

    Strouse, Gabrielle A; Nyhout, Angela; Ganea, Patricia A

    2018-01-01

    Picture books are an important source of new language, concepts, and lessons for young children. A large body of research has documented the nature of parent-child interactions during shared book reading. A new body of research has begun to investigate the features of picture books that support children's learning and transfer of that information to the real world. In this paper, we discuss how children's symbolic development, analogical reasoning, and reasoning about fantasy may constrain their ability to take away content information from picture books. We then review the nascent body of findings that has focused on the impact of picture book features on children's learning and transfer of words and letters, science concepts, problem solutions, and morals from picture books. In each domain of learning we discuss how children's development may interact with book features to impact their learning. We conclude that children's ability to learn and transfer content from picture books can be disrupted by some book features and research should directly examine the interaction between children's developing abilities and book characteristics on children's learning.

  19. Functional analysis of ultra high information rates conveyed by rat vibrissal primary afferents

    PubMed Central

    Chagas, André M.; Theis, Lucas; Sengupta, Biswa; Stüttgen, Maik C.; Bethge, Matthias; Schwarz, Cornelius

    2013-01-01

    Sensory receptors determine the type and the quantity of information available for perception. Here, we quantified and characterized the information transferred by primary afferents in the rat whisker system using neural system identification. Quantification of “how much” information is conveyed by primary afferents, using the direct method (DM), a classical information theoretic tool, revealed that primary afferents transfer huge amounts of information (up to 529 bits/s). Information theoretic analysis of instantaneous spike-triggered kinematic stimulus features was used to gain functional insight on “what” is coded by primary afferents. Amongst the kinematic variables tested—position, velocity, and acceleration—primary afferent spikes encoded velocity best. The other two variables contributed to information transfer, but only if combined with velocity. We further revealed three additional characteristics that play a role in information transfer by primary afferents. Firstly, primary afferent spikes show preference for well separated multiple stimuli (i.e., well separated sets of combinations of the three instantaneous kinematic variables). Secondly, neurons are sensitive to short strips of the stimulus trajectory (up to 10 ms pre-spike time), and thirdly, they show spike patterns (precise doublet and triplet spiking). In order to deal with these complexities, we used a flexible probabilistic neuron model fitting mixtures of Gaussians to the spike triggered stimulus distributions, which quantitatively captured the contribution of the mentioned features and allowed us to achieve a full functional analysis of the total information rate indicated by the DM. We found that instantaneous position, velocity, and acceleration explained about 50% of the total information rate. Adding a 10 ms pre-spike interval of stimulus trajectory achieved 80–90%. The final 10–20% were found to be due to non-linear coding by spike bursts. PMID:24367295

  20. Odorant transfer characteristics of white bread during baking.

    PubMed

    Onishi, Masanobu; Inoue, Michiko; Araki, Tetsuya; Iwabuchi, Hisakatsu; Sagara, Yasuyuki

    2011-01-01

    The potent odorants in the crust and crumb of white bread were identified and quantified by gas chromatography-mass spectrometry and gas chromatography/olfactometry. The weight loss ratio of the samples baked at 220 °C was controlled in the range of 0-28%. The odorants were classified into 5 types by the transfer characteristics: i) All amounts of odorant transferred from the crust to external space (type-I). ii) All transferred from the crust to the crumb and external space (type-II). iii) Certain amount remaining in the crust and the rest transferred to the crumb and external space (type-III). iv) All transferred from the crumb to external space (type-IV). v) Certain amount remaining in the crumb and the rest transferred to the crust and external space (type-V). The odorants of type-IV were not apparent after the crust had formed. The results indicate that the crust could be a barrier to prevent the odorants from being transferred to external space.

  1. Transfer of entangled state, entanglement swapping and quantum information processing via the Rydberg blockade

    NASA Astrophysics Data System (ADS)

    Deng, Li; Chen, Ai-Xi; Zhang, Jian-Song

    2011-11-01

    We provide a scheme with which the transfer of the entangled state and the entanglement swapping can be realized in a system of neutral atoms via the Rydberg blockade. Our idea can be extended to teleport an unknown atomic state. According to the latest theoretical research of the Rydberg excitation and experimental reports of the Rydberg blockade effect in quantum information processing, we discuss the experimental feasibility of our scheme.

  2. The Deceptively Simple N170 Reflects Network Information Processing Mechanisms Involving Visual Feature Coding and Transfer Across Hemispheres.

    PubMed

    Ince, Robin A A; Jaworska, Katarzyna; Gross, Joachim; Panzeri, Stefano; van Rijsbergen, Nicola J; Rousselet, Guillaume A; Schyns, Philippe G

    2016-08-22

    A key to understanding visual cognition is to determine "where", "when", and "how" brain responses reflect the processing of the specific visual features that modulate categorization behavior-the "what". The N170 is the earliest Event-Related Potential (ERP) that preferentially responds to faces. Here, we demonstrate that a paradigmatic shift is necessary to interpret the N170 as the product of an information processing network that dynamically codes and transfers face features across hemispheres, rather than as a local stimulus-driven event. Reverse-correlation methods coupled with information-theoretic analyses revealed that visibility of the eyes influences face detection behavior. The N170 initially reflects coding of the behaviorally relevant eye contralateral to the sensor, followed by a causal communication of the other eye from the other hemisphere. These findings demonstrate that the deceptively simple N170 ERP hides a complex network information processing mechanism involving initial coding and subsequent cross-hemispheric transfer of visual features. © The Author 2016. Published by Oxford University Press.

  3. The Deceptively Simple N170 Reflects Network Information Processing Mechanisms Involving Visual Feature Coding and Transfer Across Hemispheres

    PubMed Central

    Ince, Robin A. A.; Jaworska, Katarzyna; Gross, Joachim; Panzeri, Stefano; van Rijsbergen, Nicola J.; Rousselet, Guillaume A.; Schyns, Philippe G.

    2016-01-01

    A key to understanding visual cognition is to determine “where”, “when”, and “how” brain responses reflect the processing of the specific visual features that modulate categorization behavior—the “what”. The N170 is the earliest Event-Related Potential (ERP) that preferentially responds to faces. Here, we demonstrate that a paradigmatic shift is necessary to interpret the N170 as the product of an information processing network that dynamically codes and transfers face features across hemispheres, rather than as a local stimulus-driven event. Reverse-correlation methods coupled with information-theoretic analyses revealed that visibility of the eyes influences face detection behavior. The N170 initially reflects coding of the behaviorally relevant eye contralateral to the sensor, followed by a causal communication of the other eye from the other hemisphere. These findings demonstrate that the deceptively simple N170 ERP hides a complex network information processing mechanism involving initial coding and subsequent cross-hemispheric transfer of visual features. PMID:27550865

  4. Quantifying edge significance on maintaining global connectivity

    PubMed Central

    Qian, Yuhua; Li, Yebin; Zhang, Min; Ma, Guoshuai; Lu, Furong

    2017-01-01

    Global connectivity is a quite important issue for networks. The failures of some key edges may lead to breakdown of the whole system. How to find them will provide a better understanding on system robustness. Based on topological information, we propose an approach named LE (link entropy) to quantify the edge significance on maintaining global connectivity. Then we compare the LE with the other six acknowledged indices on the edge significance: the edge betweenness centrality, degree product, bridgeness, diffusion importance, topological overlap and k-path edge centrality. Experimental results show that the LE approach outperforms in quantifying edge significance on maintaining global connectivity. PMID:28349923

  5. Defining the eHealth Information Niche in the Family Physician/Patient Examination and Knowledge Transfer Process

    ERIC Educational Resources Information Center

    Ellington, Virginia Beth Elder

    2012-01-01

    This research study was undertaken to gain a richer understanding of the use of patient-introduced online health information during the physician/patient examination and knowledge transfer process. Utilizing qualitative data obtained from ten family physician interviews and workflow modeling using activity diagrams and task structure charts, this…

  6. 48 CFR 52.232-35 - Designation of Office for Government Receipt of Electronic Funds Transfer Information.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Designation of Office for Government Receipt of Electronic Funds Transfer Information. 52.232-35 Section 52.232-35 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION (CONTINUED) CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of...

  7. Quantifying three dimensional reconnection in fragmented current layers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wyper, P. F., E-mail: peter.f.wyper@nasa.gov; Hesse, M., E-mail: michael.hesse-1@nasa.gov

    There is growing evidence that when magnetic reconnection occurs in high Lundquist number plasmas such as in the Solar Corona or the Earth's Magnetosphere it does so within a fragmented, rather than a smooth current layer. Within the extent of these fragmented current regions, the associated magnetic flux transfer and energy release occur simultaneously in many different places. This investigation focusses on how best to quantify the rate at which reconnection occurs in such layers. An analytical theory is developed which describes the manner in which new connections form within fragmented current layers in the absence of magnetic nulls. Itmore » is shown that the collective rate at which new connections form can be characterized by two measures; a total rate which measures the true rate at which new connections are formed and a net rate which measures the net change of connection associated with the largest value of the integral of E{sub ||} through all of the non-ideal regions. Two simple analytical models are presented which demonstrate how each should be applied and what they quantify.« less

  8. Quantification of the Mass Transfer at Fluid Interfaces in Microfluidic Channels

    NASA Astrophysics Data System (ADS)

    Wismeth, Carina; Manhart, Michael; Niessner, Reinhard; Baumann, Thomas

    2017-04-01

    Mass transfer rates at interfaces in a complex porous media are relevant in many environmental applications and control the functions of natural filter systems in subsurface environments. The mass transfer at fluid interfaces is associated with interface convection caused by local inhomogeneities in interface tension and hydrodynamic instabilities at the interface. If there is a surface tension gradient along the surface a shear stress jump is generated that results in fluid motion along the surface that is called Marangoni effect. These spontaneous convection currents can lead to an increased mass transfer of the transition component at the phase boundary and to an increased mixing of the phases. Therefore compensatory currents at the interface can have a significant influence on the subsurface transport of contaminants in the groundwater area, especially in the vadose zone. Using microfluidic channels and advanced experimental techniques it is possible to measure the fluid flow and mass transfer rates directly and to quantify the effect of the Marangoni convection on the mass transfer at interfaces between a non-aqueous liquid and water with high temporal and spatial resolution. The use of fluorescent particles as well as the recording and analysis of their trajectories is intended to visualize interfacial processes and to quantify the mass transfer at fluid phase boundaries. Concentration gradients at the interface are analysed by spectroscopic methods and allow an assessment of the enrichment and depletion at the phase boundaries. Extensive test series provide the experimental basis for quantifying and analysing the impact of the Marangoni effect on the mass transfer rates at interfaces in porous media in subsurface aquatic environments. Within this research project we concentrate on the effect of Marangoni convection on the mass transfer near an 1-octanol-water interface, which serves as a well defined proxy for non-aqueous phase liquids in porous media

  9. Novel microscopy-based screening method reveals regulators of contact-dependent intercellular transfer

    PubMed Central

    Michael Frei, Dominik; Hodneland, Erlend; Rios-Mondragon, Ivan; Burtey, Anne; Neumann, Beate; Bulkescher, Jutta; Schölermann, Julia; Pepperkok, Rainer; Gerdes, Hans-Hermann; Kögel, Tanja

    2015-01-01

    Contact-dependent intercellular transfer (codeIT) of cellular constituents can have functional consequences for recipient cells, such as enhanced survival and drug resistance. Pathogenic viruses, prions and bacteria can also utilize this mechanism to spread to adjacent cells and potentially evade immune detection. However, little is known about the molecular mechanism underlying this intercellular transfer process. Here, we present a novel microscopy-based screening method to identify regulators and cargo of codeIT. Single donor cells, carrying fluorescently labelled endocytic organelles or proteins, are co-cultured with excess acceptor cells. CodeIT is quantified by confocal microscopy and image analysis in 3D, preserving spatial information. An siRNA-based screening using this method revealed the involvement of several myosins and small GTPases as codeIT regulators. Our data indicates that cellular protrusions and tubular recycling endosomes are important for codeIT. We automated image acquisition and analysis to facilitate large-scale chemical and genetic screening efforts to identify key regulators of codeIT. PMID:26271723

  10. Forced convective heat transfer in curved diffusers

    NASA Technical Reports Server (NTRS)

    Rojas, J.; Whitelaw, J. H.; Yianneskis, M.

    1987-01-01

    Measurements of the velocity characteristics of the flows in two curved diffusers of rectangular cross section with C and S-shaped centerlines are presented and related to measurements of wall heat transfer coefficients along the heated flat walls of the ducts. The velocity results were obtained by laser-Doppler anemometry in a water tunnel and the heat transfer results by liquid crystal thermography in a wind tunnel. The thermographic technique allowed the rapid and inexpensive measurement of wall heat transfer coefficients along flat walls of arbitrary boundary shapes with an accuracy of about 5 percent. The results show that an increase in secondary flow velocities near the heated wall causes an increase in the local wall heat transfer coefficient, and quantify the variation for maximum secondary-flow velocities in a range from 1.5 to 17 percent of the bulk flow velocity.

  11. Incremental comprehension of spoken quantifier sentences: Evidence from brain potentials.

    PubMed

    Freunberger, Dominik; Nieuwland, Mante S

    2016-09-01

    Do people incrementally incorporate the meaning of quantifier expressions to understand an unfolding sentence? Most previous studies concluded that quantifiers do not immediately influence how a sentence is understood based on the observation that online N400-effects differed from offline plausibility judgments. Those studies, however, used serial visual presentation (SVP), which involves unnatural reading. In the current ERP-experiment, we presented spoken positive and negative quantifier sentences ("Practically all/practically no postmen prefer delivering mail, when the weather is good/bad during the day"). Different from results obtained in a previously reported SVP-study (Nieuwland, 2016) sentence truth-value N400 effects occurred in positive and negative quantifier sentences alike, reflecting fully incremental quantifier comprehension. This suggests that the prosodic information available during spoken language comprehension supports the generation of online predictions for upcoming words and that, at least for quantifier sentences, comprehension of spoken language may proceed more incrementally than comprehension during SVP reading. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

  12. Electron Transfer Dissociation of iTRAQ Labeled Peptide Ions

    PubMed Central

    Han, Hongling; Pappin, Darryl J.; Ross, Philip L; McLuckey, Scott A.

    2009-01-01

    Triply and doubly charged iTRAQ (isobaric tagging for relative and absolute quantitation) labeled peptide cations from a tryptic peptide mixture of bovine carbonic anhydrase II were subjected to electron transfer ion/ion reactions to investigate the effect of charge bearing modifications associated with iTRAQ on the fragmentation pattern. It was noted that electron transfer dissociation (ETD) of triply charged or activated ETD (ETD + supplemental collisional activation of intact electron transfer species) of doubly charged iTRAQ tagged peptide ions yielded extensive sequence information, in analogy with ETD of unmodified peptide ions. That is, addition of the fixed charge iTRAQ tag showed relatively little deleterious effect on the ETD performance of the modified peptides. ETD of the triply charged iTRAQ labeled peptide ions followed by collision-induced dissociation (CID) of the product ion at m/z 162 yielded the reporter ion at m/z 116, which is the reporter ion used for quantitation via CID of the same precursor ions. The reporter ion formed via the two-step activation process is expected to provide quantitative information similar to that directly produced from CID. A 103 Da neutral loss species observed in the ETD spectra of all the triply and doubly charged iTRAQ labeled peptide ions is unique to the 116 Da iTRAQ reagent, which implies that this process also has potential for quantitation of peptides/proteins. Therefore, ETD with or without supplemental collisional activation, depending on the precursor ion charge state, has the potential to directly identify and quantify the peptides/proteins simultaneously using existing iTRAQ reagents. PMID:18646790

  13. Introduction of the identification, situation, background, assessment, recommendations tool to improve the quality of information transfer during medical handover in intensive care.

    PubMed

    Ramasubbu, Benjamin; Stewart, Emma; Spiritoso, Rosalba

    2017-02-01

    To audit the quality and safety of the current doctor-to-doctor handover of patient information in our Cardiothoracic Intensive Care Unit. If deficient, to implement a validated handover tool to improve the quality of the handover process. In Cycle 1 we observed the verbal handover and reviewed the written handover information transferred for 50 consecutive patients in St George's Hospital Cardiothoracic Intensive Care Unit. For each patient's handover, we assessed whether each section of the Identification, Situation, Background, Assessment, Recommendations tool was used on a scale of 0-2. Zero if no information in that category was transferred, one if the information was partially transferred and two if all relevant information was transferred. Each patient's handover received a score from 0 to 10 and thus, each cycle a total score of 0-500. Following the implementation of the Identification, Situation, Background, Assessment, Recommendations handover tool in our Intensive Care Unit in Cycle 2, we re-observed the handover process for another 50 consecutive patients hence, completing the audit cycle. There was a significant difference between the total scores from Cycle 1 and 2 (263/500 versus 457/500, p < 0.001). The median handover score for Cycle 1 was 5/10 (interquartile range 4-6). The median handover score for Cycle 2 was 9/10 (interquartile range 9-10). Patient handover scores increased significantly between Cycle 1 and 2, U = 13.5, p < 0.001. The introduction of a standardised handover template (Identification, Situation, Background, Assessment, Recommendations tool) has improved the quality and safety of the doctor-to-doctor handover of patient information in our Intensive Care Unit.

  14. Report of a Planning Conference for Solar Technology Information Transfer (Nashville, Tennessee, September 28-29, 1977).

    ERIC Educational Resources Information Center

    Gleaves, Edwin S., Ed.

    A summary of the deliberations of the Planning Conference for Solar Technology Information Transfer--to discuss and outline a functioning solar energy technology network in the State of Tennessee--and a set of recommendations for future action are presented in this report. Topic areas include: (1) the Tennessee Regional Library Service; (2) the…

  15. Novel and highly informative Capsicum SSR markers and their cross-species transferability.

    PubMed

    Buso, G S C; Reis, A M M; Amaral, Z P S; Ferreira, M E

    2016-09-23

    This study was undertaken primarily to develop new simple sequence repeat (SSR) markers for Capsicum. As part of this project aimed at broadening the use of molecular tools in Capsicum breeding, two genomic libraries enriched for AG/TC repeat sequences were constructed for Capsicum annuum. A total of 475 DNA clones were sequenced from both libraries and 144 SSR markers were tested on cultivated and wild species of Capsicum. Forty-five SSR markers were randomly selected to genotype a panel of 48 accessions of the Capsicum germplasm bank. The number of alleles per locus ranged from 2 to 11, with an average of 6 alleles. The polymorphism information content was on average 0.60, ranging from 0.20 to 0.83. The cross-species transferability to seven cultivated and wild Capsicum species was tested with a set of 91 SSR markers. We found that a high proportion of the loci produced amplicons in all species tested. C. frutescens had the highest number of transferable markers, whereas the wild species had the lowest. Our results indicate that the new markers can be readily used in genetic analyses of Capsicum.

  16. Leveraging anatomical information to improve transfer learning in brain-computer interfaces.

    PubMed

    Wronkiewicz, Mark; Larson, Eric; Lee, Adrian K C

    2015-08-01

    Brain-computer interfaces (BCIs) represent a technology with the potential to rehabilitate a range of traumatic and degenerative nervous system conditions but require a time-consuming training process to calibrate. An area of BCI research known as transfer learning is aimed at accelerating training by recycling previously recorded training data across sessions or subjects. Training data, however, is typically transferred from one electrode configuration to another without taking individual head anatomy or electrode positioning into account, which may underutilize the recycled data. We explore transfer learning with the use of source imaging, which estimates neural activity in the cortex. Transferring estimates of cortical activity, in contrast to scalp recordings, provides a way to compensate for variability in electrode positioning and head morphologies across subjects and sessions. Based on simulated and measured electroencephalography activity, we trained a classifier using data transferred exclusively from other subjects and achieved accuracies that were comparable to or surpassed a benchmark classifier (representative of a real-world BCI). Our results indicate that classification improvements depend on the number of trials transferred and the cortical region of interest. These findings suggest that cortical source-based transfer learning is a principled method to transfer data that improves BCI classification performance and provides a path to reduce BCI calibration time.

  17. Information dynamics of brain-heart physiological networks during sleep

    NASA Astrophysics Data System (ADS)

    Faes, L.; Nollo, G.; Jurysta, F.; Marinazzo, D.

    2014-10-01

    This study proposes an integrated approach, framed in the emerging fields of network physiology and information dynamics, for the quantitative analysis of brain-heart interaction networks during sleep. With this approach, the time series of cardiac vagal autonomic activity and brain wave activities measured respectively as the normalized high frequency component of heart rate variability and the EEG power in the δ, θ, α, σ, and β bands, are considered as realizations of the stochastic processes describing the dynamics of the heart system and of different brain sub-systems. Entropy-based measures are exploited to quantify the predictive information carried by each (sub)system, and to dissect this information into a part actively stored in the system and a part transferred to it from the other connected systems. The application of this approach to polysomnographic recordings of ten healthy subjects led us to identify a structured network of sleep brain-brain and brain-heart interactions, with the node described by the β EEG power acting as a hub which conveys the largest amount of information flowing between the heart and brain nodes. This network was found to be sustained mostly by the transitions across different sleep stages, as the information transfer was weaker during specific stages than during the whole night, and vanished progressively when moving from light sleep to deep sleep and to REM sleep.

  18. Satisfaction Levels and Factors Influencing Satisfaction With Use of a Social App for Neonatal and Pediatric Patient Transfer Information Systems: A Questionnaire Study Among Doctors

    PubMed Central

    Choi, Iee; Kim, Sun Jun; Cho, Soo Chul; Kim, Il Nyeo

    2016-01-01

    Background The treatment of neonatal and pediatric patients is limited to certain medical institutions depending on treatment difficulty. Effective patient transfers are necessary in situations where there are limited medical resources. In South Korea, the government has made a considerable effort to establish patient transfer systems using various means, such as websites, telephone, and so forth. However, in reality, the effort has not yet been effective. Objective In this study, we ran a patient transfer information system using a social app for effective patient transfer. We analyzed the results, satisfaction levels, and the factors influencing satisfaction. Methods Naver Band is a social app and mobile community application which in Korea is more popular than Facebook. It facilitates group communication. Using Naver Band, two systems were created: one by the Neonatal Intensive Care Unit and the other by the Department of Pediatrics at Chonbuk National University Children's Hospital, South Korea. The information necessary for patient transfers was provided to participating obstetricians (n=51) and pediatricians (n=90). We conducted a survey to evaluate the systems and reviewed the results retrospectively. Results The number of patients transferred was reported to increase by 65% (26/40) obstetricians and 40% (23/57) pediatricians. The time taken for transfers was reported to decrease by 72% (29/40) obstetricians and 59% (34/57) pediatricians. Satisfaction was indicated by 83% (33/40) obstetricians and 89% (51/57) pediatricians. Regarding factors influencing satisfaction, the obstetricians reported communication with doctors in charge (P=.03) and time reduction during transfers (P=.02), whereas the pediatricians indicated review of the diagnosis and treatment of transferred patients (P=.01) and the time reduction during transfers (P=.007). Conclusions The users were highly satisfied and different users indicated different factors of satisfaction. This finding

  19. Satisfaction Levels and Factors Influencing Satisfaction With Use of a Social App for Neonatal and Pediatric Patient Transfer Information Systems: A Questionnaire Study Among Doctors.

    PubMed

    Choi, Iee; Kim, Jin Kyu; Kim, Sun Jun; Cho, Soo Chul; Kim, Il Nyeo

    2016-08-04

    The treatment of neonatal and pediatric patients is limited to certain medical institutions depending on treatment difficulty. Effective patient transfers are necessary in situations where there are limited medical resources. In South Korea, the government has made a considerable effort to establish patient transfer systems using various means, such as websites, telephone, and so forth. However, in reality, the effort has not yet been effective. In this study, we ran a patient transfer information system using a social app for effective patient transfer. We analyzed the results, satisfaction levels, and the factors influencing satisfaction. Naver Band is a social app and mobile community application which in Korea is more popular than Facebook. It facilitates group communication. Using Naver Band, two systems were created: one by the Neonatal Intensive Care Unit and the other by the Department of Pediatrics at Chonbuk National University Children's Hospital, South Korea. The information necessary for patient transfers was provided to participating obstetricians (n=51) and pediatricians (n=90). We conducted a survey to evaluate the systems and reviewed the results retrospectively. The number of patients transferred was reported to increase by 65% (26/40) obstetricians and 40% (23/57) pediatricians. The time taken for transfers was reported to decrease by 72% (29/40) obstetricians and 59% (34/57) pediatricians. Satisfaction was indicated by 83% (33/40) obstetricians and 89% (51/57) pediatricians. Regarding factors influencing satisfaction, the obstetricians reported communication with doctors in charge (P=.03) and time reduction during transfers (P=.02), whereas the pediatricians indicated review of the diagnosis and treatment of transferred patients (P=.01) and the time reduction during transfers (P=.007). The users were highly satisfied and different users indicated different factors of satisfaction. This finding implies that users' requirements should be

  20. Quantifiers more or less quantify online: ERP evidence for partial incremental interpretation

    PubMed Central

    Urbach, Thomas P.; Kutas, Marta

    2010-01-01

    Event-related brain potentials were recorded during RSVP reading to test the hypothesis that quantifier expressions are incrementally interpreted fully and immediately. In sentences tapping general knowledge (Farmers grow crops/worms as their primary source of income), Experiment 1 found larger N400s for atypical (worms) than typical objects (crops). Experiment 2 crossed object typicality with non-logical subject-noun phrase quantifiers (most, few). Off-line plausibility ratings exhibited the crossover interaction predicted by full quantifier interpretation: Most farmers grow crops and Few farmers grow worms were rated more plausible than Most farmers grow worms and Few farmers grow crops. Object N400s, although modulated in the expected direction, did not reverse. Experiment 3 replicated these findings with adverbial quantifiers (Farmers often/rarely grow crops/worms). Interpretation of quantifier expressions thus is neither fully immediate nor fully delayed. Furthermore, object atypicality was associated with a frontal slow positivity in few-type/rarely quantifier contexts, suggesting systematic processing differences among quantifier types. PMID:20640044

  1. Transfer Entropy as a Log-Likelihood Ratio

    NASA Astrophysics Data System (ADS)

    Barnett, Lionel; Bossomaier, Terry

    2012-09-01

    Transfer entropy, an information-theoretic measure of time-directed information transfer between joint processes, has steadily gained popularity in the analysis of complex stochastic dynamics in diverse fields, including the neurosciences, ecology, climatology, and econometrics. We show that for a broad class of predictive models, the log-likelihood ratio test statistic for the null hypothesis of zero transfer entropy is a consistent estimator for the transfer entropy itself. For finite Markov chains, furthermore, no explicit model is required. In the general case, an asymptotic χ2 distribution is established for the transfer entropy estimator. The result generalizes the equivalence in the Gaussian case of transfer entropy and Granger causality, a statistical notion of causal influence based on prediction via vector autoregression, and establishes a fundamental connection between directed information transfer and causality in the Wiener-Granger sense.

  2. Transfer entropy as a log-likelihood ratio.

    PubMed

    Barnett, Lionel; Bossomaier, Terry

    2012-09-28

    Transfer entropy, an information-theoretic measure of time-directed information transfer between joint processes, has steadily gained popularity in the analysis of complex stochastic dynamics in diverse fields, including the neurosciences, ecology, climatology, and econometrics. We show that for a broad class of predictive models, the log-likelihood ratio test statistic for the null hypothesis of zero transfer entropy is a consistent estimator for the transfer entropy itself. For finite Markov chains, furthermore, no explicit model is required. In the general case, an asymptotic χ2 distribution is established for the transfer entropy estimator. The result generalizes the equivalence in the Gaussian case of transfer entropy and Granger causality, a statistical notion of causal influence based on prediction via vector autoregression, and establishes a fundamental connection between directed information transfer and causality in the Wiener-Granger sense.

  3. Towards understanding the behavior of physical systems using information theory

    NASA Astrophysics Data System (ADS)

    Quax, Rick; Apolloni, Andrea; Sloot, Peter M. A.

    2013-09-01

    One of the goals of complex network analysis is to identify the most influential nodes, i.e., the nodes that dictate the dynamics of other nodes. In the case of autonomous systems or transportation networks, highly connected hubs play a preeminent role in diffusing the flow of information and viruses; in contrast, in language evolution most linguistic norms come from the peripheral nodes who have only few contacts. Clearly a topological analysis of the interactions alone is not sufficient to identify the nodes that drive the state of the network. Here we show how information theory can be used to quantify how the dynamics of individual nodes propagate through a system. We interpret the state of a node as a storage of information about the state of other nodes, which is quantified in terms of Shannon information. This information is transferred through interactions and lost due to noise, and we calculate how far it can travel through a network. We apply this concept to a model of opinion formation in a complex social network to calculate the impact of each node by measuring how long its opinion is remembered by the network. Counter-intuitively we find that the dynamics of opinions are not determined by the hubs or peripheral nodes, but rather by nodes with an intermediate connectivity.

  4. Leveraging anatomical information to improve transfer learning in brain-computer interfaces

    NASA Astrophysics Data System (ADS)

    Wronkiewicz, Mark; Larson, Eric; Lee, Adrian K. C.

    2015-08-01

    Objective. Brain-computer interfaces (BCIs) represent a technology with the potential to rehabilitate a range of traumatic and degenerative nervous system conditions but require a time-consuming training process to calibrate. An area of BCI research known as transfer learning is aimed at accelerating training by recycling previously recorded training data across sessions or subjects. Training data, however, is typically transferred from one electrode configuration to another without taking individual head anatomy or electrode positioning into account, which may underutilize the recycled data. Approach. We explore transfer learning with the use of source imaging, which estimates neural activity in the cortex. Transferring estimates of cortical activity, in contrast to scalp recordings, provides a way to compensate for variability in electrode positioning and head morphologies across subjects and sessions. Main results. Based on simulated and measured electroencephalography activity, we trained a classifier using data transferred exclusively from other subjects and achieved accuracies that were comparable to or surpassed a benchmark classifier (representative of a real-world BCI). Our results indicate that classification improvements depend on the number of trials transferred and the cortical region of interest. Significance. These findings suggest that cortical source-based transfer learning is a principled method to transfer data that improves BCI classification performance and provides a path to reduce BCI calibration time.

  5. Leveraging anatomical information to improve transfer learning in brain-computer interfaces

    PubMed Central

    Wronkiewicz, Mark; Larson, Eric; Lee, Adrian KC

    2015-01-01

    Objective Brain-computer interfaces (BCIs) represent a technology with the potential to rehabilitate a range of traumatic and degenerative nervous system conditions but require a time-consuming training process to calibrate. An area of BCI research known as transfer learning is aimed at accelerating training by recycling previously recorded training data across sessions or subjects. Training data, however, is typically transferred from one electrode configuration to another without taking individual head anatomy or electrode positioning into account, which may underutilize the recycled data. Approach We explore transfer learning with the use of source imaging, which estimates neural activity in the cortex. Transferring estimates of cortical activity, in contrast to scalp recordings, provides a way to compensate for variability in electrode positioning and head morphologies across subjects and sessions. Main Results Based on simulated and measured EEG activity, we trained a classifier using data transferred exclusively from other subjects and achieved accuracies that were comparable to or surpassed a benchmark classifier (representative of a real-world BCI). Our results indicate that classification improvements depend on the number of trials transferred and the cortical region of interest. Significance These findings suggest that cortical source-based transfer learning is a principled method to transfer data that improves BCI classification performance and provides a path to reduce BCI calibration time. PMID:26169961

  6. Dissolved oxygen transfer to sediments by sweep and eject motions in aquatic environments

    USGS Publications Warehouse

    O'Connor, B.L.; Hondzo, Miki

    2008-01-01

    Dissolved oxygen (DO) concentrations were quantified near the sediment-water interface to evaluate DO transfer to sediments in a laboratory recirculating flume and open channel under varying fluid-flow conditions. DO concentration fluctuations were observed within the diffusive sublayer, as defined by the time-averaged DO concentration gradient near the sediment-water interface. Evaluation of the DO concentration fluctuations along with detailed fluid-flow characterizations were used to quantify quasi-periodic sweep and eject motions (bursting events) near the sediments. Bursting events dominated the Reynolds shear stresses responsible for momentum and mass fluctuations near the sediment bed. Two independent methods for detecting bursting events using DO concentration and velocity data produced consistent results. The average time between bursting events was scaled with wall variables and was incorporated into a similarity model to describe the dimensionless mass transfer coefficient (Sherwood number, Sh) in terms of the Reynolds number, Re, and Schmidt number, Sc, which described transport in the flow. The scaling of bursting events was employed with the similarity model to quantify DO transfer to sediments and results showed a high degree of agreement with experimental data. ?? 2008, by the American Society of Limnology and Oceanography, Inc.

  7. Trophic transfer of microplastics in aquatic ecosystems: Identifying critical research needs.

    PubMed

    Au, Sarah Y; Lee, Cindy M; Weinstein, John E; van den Hurk, Peter; Klaine, Stephen J

    2017-05-01

    To evaluate the process of trophic transfer of microplastics, it is important to consider various abiotic and biotic factors involved in their ingestion, egestion, bioaccumulation, and biomagnification. Toward this end, a review of the literature on microplastics has been conducted to identify factors influencing their uptake and absorption; their residence times in organisms and bioaccumulation; the physical effects of their aggregation in gastrointestinal tracts; and their potential to act as vectors for the transfer of other contaminants. Limited field evidence from higher trophic level organisms in a variety of habitats suggests that trophic transfer of microplastics may be a common phenomenon and occurs concurrently with direct ingestion. Critical research needs include standardizing methods of field characterization of microplastics, quantifying uptake and depuration rates in organisms at different trophic levels, quantifying the influence that microplastics have on the uptake and/or depuration of environmental contaminants among different trophic levels, and investigating the potential for biomagnification of microplastic-associated chemicals. More integrated approaches involving computational modeling are required to fully assess trophic transfer of microplastics. Integr Environ Assess Manag 2017;13:505-509. © 2017 SETAC. © 2017 SETAC.

  8. Tactile information transfer: A comparison of two stimulation sites

    NASA Astrophysics Data System (ADS)

    Summers, Ian R.; Whybrow, Jon J.; Gratton, Denise A.; Milnes, Peter; Brown, Brian H.; Stevens, John C.

    2005-10-01

    Two experiments on the discrimination of time-varying tactile stimuli were performed, with comparison of stimulus delivery to the distal pad of the right index finger and to the right wrist (palmar surface). Subjects were required to perceive differences in short sequences of computer-generated stimulus elements (experiment 1) or differences in short tactile stimuli derived from a speech signal (experiment 2). The pulse-train stimuli were distinguished by differences in frequency (i.e., pulse repetition rate) and amplitude, and by the presence/absence of gaps (~100-ms duration). Stimulation levels were 10 dB higher at the wrist than at the fingertip, to compensate for the lower vibration sensitivity at the wrist. Results indicate similar gap detection at wrist and fingertip and similar perception of frequency differences. However, perception of amplitude differences was found to be better at the wrist than at the fingertip. Maximum information transfer rates for the stimuli in experiment 1 were estimated at 7 bits s-1 at the wrist and 5 bits s-1 at the fingertip.

  9. Tactile information transfer: a comparison of two stimulation sites.

    PubMed

    Summers, lan R; Whybrow, Jon J; Gratton, Denise A; Milnes, Peter; Brown, Brian H; Stevens, John C

    2005-10-01

    Two experiments on the discrimination of time-varying tactile stimuli were performed, with comparison of stimulus delivery to the distal pad of the right index finger and to the right wrist (palmar surface). Subjects were required to perceive differences in short sequences of computer-generated stimulus elements (experiment 1) or differences in short tactile stimuli derived from a speech signal (experiment 2). The pulse-train stimuli were distinguished by differences in frequency (i.e., pulse repetition rate) and amplitude, and by the presence/absence of gaps (approximately 100-ms duration). Stimulation levels were 10 dB higher at the wrist than at the fingertip, to compensate for the lower vibration sensitivity at the wrist. Results indicate similar gap detection at wrist and fingertip and similar perception of frequency differences. However, perception of amplitude differences was found to be better at the wrist than at the fingertip. Maximum information transfer rates for the stimuli in experiment 1 were estimated at 7 bits s(-1) at the wrist and 5 bits s(-1) at the fingertip.

  10. Optimal decoding and information transmission in Hodgkin-Huxley neurons under metabolic cost constraints.

    PubMed

    Kostal, Lubomir; Kobayashi, Ryota

    2015-10-01

    Information theory quantifies the ultimate limits on reliable information transfer by means of the channel capacity. However, the channel capacity is known to be an asymptotic quantity, assuming unlimited metabolic cost and computational power. We investigate a single-compartment Hodgkin-Huxley type neuronal model under the spike-rate coding scheme and address how the metabolic cost and the decoding complexity affects the optimal information transmission. We find that the sub-threshold stimulation regime, although attaining the smallest capacity, allows for the most efficient balance between the information transmission and the metabolic cost. Furthermore, we determine post-synaptic firing rate histograms that are optimal from the information-theoretic point of view, which enables the comparison of our results with experimental data. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  11. Characterization of autoregressive processes using entropic quantifiers

    NASA Astrophysics Data System (ADS)

    Traversaro, Francisco; Redelico, Francisco O.

    2018-01-01

    The aim of the contribution is to introduce a novel information plane, the causal-amplitude informational plane. As previous works seems to indicate, Bandt and Pompe methodology for estimating entropy does not allow to distinguish between probability distributions which could be fundamental for simulation or for probability analysis purposes. Once a time series is identified as stochastic by the causal complexity-entropy informational plane, the novel causal-amplitude gives a deeper understanding of the time series, quantifying both, the autocorrelation strength and the probability distribution of the data extracted from the generating processes. Two examples are presented, one from climate change model and the other from financial markets.

  12. The subscale orbital fluid transfer experiment

    NASA Technical Reports Server (NTRS)

    Meserole, J. S.; Collins, Frank G.; Jones, Ogden; Antar, Basil; Menzel, Reinhard; Gray, Perry

    1995-01-01

    The work during the present year consisted of examining concepts for visual observation of the fluid transfer process, examination of methods for accurately metering the amount of liquid transferred between the two tanks, examination of possible test fluids, and consideration of the materials to use for the elastomeric diaphragm. The objective of the visual observation is to locate the fluid-vapor interfaces and, if possible, quantify the amount of vapor and the area of the interface. It is proposed to use video cameras to view the overall process in each tank and to place borescopes or other devices through the tank walls to obtain detailed, undistorted views inside the tanks of critical portions of the transfer process. Further work will continue to find an economical means for providing this detailed view, which clearly would increase the data obtained from the experiment.

  13. A Simple, Visually Oriented Communication System to Improve Postoperative Care Following Microvascular Free Tissue Transfer: Development, Results, and Implications.

    PubMed

    Henderson, Peter W; Landford, Wilmina; Gardenier, Jason; Otterburn, David M; Rohde, Christine H; Spector, Jason A

    2016-07-01

    Background Communication, particularly transmission of information between the surgical and nursing teams, has been identified as one of the most crucial determinants of patient outcomes. Nonetheless, transfer of information among and between the physician and nursing teams in the immediate postoperative period is often informal, verbal, and inconsistent. Methods An iterative process of multidisciplinary information gathering was undertaken to create a novel postoperative communication system (the "Pop-form"). Once developed, nurses were surveyed on multiple measures regarding the perceived likelihood that it would improve their ability to provide directed patient care. Data were quantified using a Likert scale (0-10), and statistically analyzed. Results The Pop-form records and transfers operative details, specific anatomic monitoring parameters, and senior physician contact information. Sixty-eight nurses completed surveys. The perceived usefulness of different components of the Pop-form system was as follows: 8.9 for the description of the procedure; 9.3 for the operative diagram; 9.4 for the monitoring details and parameters; and 9.4 for the direct contact information for the appropriate surgical team member. All respondents were in favor of widespread adoption of the Pop-form. Conclusion This uniform, visual communication system requires less than 1 minute to compose, yet formalizes and standardizes inter-team communication, and therefore shows promise for improving outcomes following microvascular free tissue transfer. We believe that this simple, innovative communication tool has the potential to be more broadly applied to many other health care settings. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  14. An information transfer based novel framework for fault root cause tracing of complex electromechanical systems in the processing industry

    NASA Astrophysics Data System (ADS)

    Wang, Rongxi; Gao, Xu; Gao, Jianmin; Gao, Zhiyong; Kang, Jiani

    2018-02-01

    As one of the most important approaches for analyzing the mechanism of fault pervasion, fault root cause tracing is a powerful and useful tool for detecting the fundamental causes of faults so as to prevent any further propagation and amplification. Focused on the problems arising from the lack of systematic and comprehensive integration, an information transfer-based novel data-driven framework for fault root cause tracing of complex electromechanical systems in the processing industry was proposed, taking into consideration the experience and qualitative analysis of conventional fault root cause tracing methods. Firstly, an improved symbolic transfer entropy method was presented to construct a directed-weighted information model for a specific complex electromechanical system based on the information flow. Secondly, considering the feedback mechanisms in the complex electromechanical systems, a method for determining the threshold values of weights was developed to explore the disciplines of fault propagation. Lastly, an iterative method was introduced to identify the fault development process. The fault root cause was traced by analyzing the changes in information transfer between the nodes along with the fault propagation pathway. An actual fault root cause tracing application of a complex electromechanical system is used to verify the effectiveness of the proposed framework. A unique fault root cause is obtained regardless of the choice of the initial variable. Thus, the proposed framework can be flexibly and effectively used in fault root cause tracing for complex electromechanical systems in the processing industry, and formulate the foundation of system vulnerability analysis and condition prediction, as well as other engineering applications.

  15. Information Literacy Practices and Student Protests: Mapping Community Information Landscapes

    ERIC Educational Resources Information Center

    Špiranec, Sonja; Kos, Denis

    2013-01-01

    Introduction: This paper provides a contribution to understandings of information literacy regarding context and transferability of information practices. Specifically, the paper analyses the subset of information practices in situations of student protests and addresses issues of transfer of information literacy practice from a highly formal…

  16. Modeling Current Transfer from PV Modules Based on Meteorological Data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hacke, Peter; Smith, Ryan; Kurtz, Sarah

    2016-11-21

    Current transferred from the active cell circuit to ground in modules undergoing potential-induced degradation (PID) stress is analyzed with respect to meteorological data. Duration and coulombs transferred as a function of whether the module is wet (from dew or rain) or the extent of uncondensed surface humidity are quantified based on meteorological indicators. With this, functions predicting the mode and rate of coulomb transfer are developed for use in estimating the relative PID stress associated with temperature, moisture, and system voltage in any climate. Current transfer in a framed crystalline silicon module is relatively high when there is no condensedmore » water on the module, whereas current transfer in a thin-film module held by edge clips is not, and displays a greater fraction of coulombs transferred when wet compared to the framed module in the natural environment.« less

  17. Do We Know What We're Simulating? Information Loss on Transferring Unconscious Perceptual Simulation to Conscious Imagery

    ERIC Educational Resources Information Center

    Connell, Louise; Lynott, Dermot

    2016-01-01

    Perceptual simulations are unconscious and automatic, whereas perceptual imagery is conscious and deliberate, but it is unclear how easily one can transfer perceptual information from unconscious to conscious awareness. We investigated whether it is possible to be aware of what one is mentally representing; that is, whether it is possible to…

  18. INVESTIGATION OF TRANSFER OF FLUORESCENT TRACERS FROM SURFACES TO SKIN

    EPA Science Inventory

    Under the provisions of the Food Quality Protection Act (FQPA), aggregate exposure assessments must be conducted for pesticides proposed for registration. Many aspects of dermal exposure assessment remain poorly quantified. For purposes of assessing surface-to-skin transfers ...

  19. Interactive web-based format vs conventional brochure material for information transfer to children and parents: a randomized controlled trial regarding preoperative information.

    PubMed

    Lööf, Gunilla; Liljeberg, Cecilia; Eksborg, Staffan; Lönnqvist, Per-Arne

    2017-06-01

    Information transfer to patients is an integral part of modern medicine. Internet-based alternatives represent a new and attractive way for information transfer. The study used a prospective observer-blinded design. Children (3-12 years) and parents were instructed to get further preoperative information either through an interactive web-based platform, the Anaesthesia-Web, or conventional brochure material until day of outpatient surgery. On the day of surgery, children and parents were separately asked six different questions. The primary end-point was to compare the total question score in children between the two information options (maximum score = 36). Secondary aims were the total question score for parents and the influence of age, sex, and time between the preoperative visit and day of surgery. A total of 125 children were recruited, of which 103 were included in the final analysis (the Anaesthesia-Web group, n = 49; the brochure material group, n = 54). At the predetermined interim analysis, the total question score in children was found to be substantially higher in the Anaesthesia-Web group than in the brochure material group (median score: 27; IQR: 16.5-33 and median score: 19.5; IQR: 11.25-27.75, respectively, P = 0.0076). The median difference in score was 6; 95% CI: 0-9. The total question score in parents was also higher in the Anaesthesia-Web group than in the brochure material group. Increasing child age was associated with a higher total question score in both groups. Sex did not influence the total question score in the Anaesthesia-Web group, whereas girls scored better than boys in the brochure material group. Children in the age range 3-12 years of age as well as their parents do better attain preoperative information from an interactive web-based platform compared to conventional brochure material. © 2017 John Wiley & Sons Ltd.

  20. Mutual Information and Information Gating in Synfire Chains

    DOE PAGES

    Xiao, Zhuocheng; Wang, Binxu; Sornborger, Andrew Tyler; ...

    2018-02-01

    Here, coherent neuronal activity is believed to underlie the transfer and processing of information in the brain. Coherent activity in the form of synchronous firing and oscillations has been measured in many brain regions and has been correlated with enhanced feature processing and other sensory and cognitive functions. In the theoretical context, synfire chains and the transfer of transient activity packets in feedforward networks have been appealed to in order to describe coherent spiking and information transfer. Recently, it has been demonstrated that the classical synfire chain architecture, with the addition of suitably timed gating currents, can support the gradedmore » transfer of mean firing rates in feedforward networks (called synfire-gated synfire chains—SGSCs). Here we study information propagation in SGSCs by examining mutual information as a function of layer number in a feedforward network. We explore the effects of gating and noise on information transfer in synfire chains and demonstrate that asymptotically, two main regions exist in parameter space where information may be propagated and its propagation is controlled by pulse-gating: a large region where binary codes may be propagated, and a smaller region near a cusp in parameter space that supports graded propagation across many layers.« less

  1. Mutual Information and Information Gating in Synfire Chains

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Xiao, Zhuocheng; Wang, Binxu; Sornborger, Andrew Tyler

    Here, coherent neuronal activity is believed to underlie the transfer and processing of information in the brain. Coherent activity in the form of synchronous firing and oscillations has been measured in many brain regions and has been correlated with enhanced feature processing and other sensory and cognitive functions. In the theoretical context, synfire chains and the transfer of transient activity packets in feedforward networks have been appealed to in order to describe coherent spiking and information transfer. Recently, it has been demonstrated that the classical synfire chain architecture, with the addition of suitably timed gating currents, can support the gradedmore » transfer of mean firing rates in feedforward networks (called synfire-gated synfire chains—SGSCs). Here we study information propagation in SGSCs by examining mutual information as a function of layer number in a feedforward network. We explore the effects of gating and noise on information transfer in synfire chains and demonstrate that asymptotically, two main regions exist in parameter space where information may be propagated and its propagation is controlled by pulse-gating: a large region where binary codes may be propagated, and a smaller region near a cusp in parameter space that supports graded propagation across many layers.« less

  2. Quantifying and reducing model-form uncertainties in Reynolds-averaged Navier-Stokes simulations: A data-driven, physics-informed Bayesian approach

    NASA Astrophysics Data System (ADS)

    Xiao, H.; Wu, J.-L.; Wang, J.-X.; Sun, R.; Roy, C. J.

    2016-11-01

    Despite their well-known limitations, Reynolds-Averaged Navier-Stokes (RANS) models are still the workhorse tools for turbulent flow simulations in today's engineering analysis, design and optimization. While the predictive capability of RANS models depends on many factors, for many practical flows the turbulence models are by far the largest source of uncertainty. As RANS models are used in the design and safety evaluation of many mission-critical systems such as airplanes and nuclear power plants, quantifying their model-form uncertainties has significant implications in enabling risk-informed decision-making. In this work we develop a data-driven, physics-informed Bayesian framework for quantifying model-form uncertainties in RANS simulations. Uncertainties are introduced directly to the Reynolds stresses and are represented with compact parameterization accounting for empirical prior knowledge and physical constraints (e.g., realizability, smoothness, and symmetry). An iterative ensemble Kalman method is used to assimilate the prior knowledge and observation data in a Bayesian framework, and to propagate them to posterior distributions of velocities and other Quantities of Interest (QoIs). We use two representative cases, the flow over periodic hills and the flow in a square duct, to evaluate the performance of the proposed framework. Both cases are challenging for standard RANS turbulence models. Simulation results suggest that, even with very sparse observations, the obtained posterior mean velocities and other QoIs have significantly better agreement with the benchmark data compared to the baseline results. At most locations the posterior distribution adequately captures the true model error within the developed model form uncertainty bounds. The framework is a major improvement over existing black-box, physics-neutral methods for model-form uncertainty quantification, where prior knowledge and details of the models are not exploited. This approach has

  3. Improved digital transfer of the maxillary cast to a virtual articulator.

    PubMed

    Solaberrieta, Eneko; Otegi, Jose Ramon; Mínguez, Rikardo; Etxaniz, Olatz

    2014-10-01

    The clinical procedure described provides a quantifiable, repeatable, and reliable method of transferring the location of the maxillary dental arch from the patient directly to a virtual articulator (virtual facebow transfer) by means of reverse engineering devices to design a customized dental restoration. This procedure allows the dentist and the dental laboratory technician to work in a fully digital environment without having to mount stone casts on a mechanical articulator. In addition, specific suggestions are provided for designing the transfer device to enhance patient comfort during the data transfer process and reduce deviation. Copyright © 2014 Editorial Council for the Journal of Prosthetic Dentistry. Published by Elsevier Inc. All rights reserved.

  4. Isolating and quantifying cross-beam energy transfer in direct-drive implosions on OMEGA and the National Ignition Facility

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Davis, A. K., E-mail: adavi@lle.rochester.edu; Cao, D.; Michel, D. T.

    The angularly resolved mass ablation rates and ablation-front trajectories for Si-coated CH targets were measured in direct-drive inertial confinement fusion experiments to quantify cross-beam energy transfer (CBET) while constraining the hydrodynamic coupling. A polar-direct-drive laser configuration, where the equatorial laser beams were dropped and the polar beams were repointed from a symmetric direct-drive configuration, was used to limit CBET at the pole while allowing it to persist at the equator. The combination of low- and high-CBET conditions observed in the same implosion allowed for the effects of CBET on the ablation rate and ablation pressure to be determined. Hydrodynamic simulationsmore » performed without CBET agreed with the measured ablation rate and ablation-front trajectory at the pole of the target, confirming that the CBET effects on the pole are small. The simulated mass ablation rates and ablation-front trajectories were in excellent agreement with the measurements at all angles when a CBET model based on Randall's equations [C. J. Randall et al., Phys. Fluids 24, 1474 (1981)] was included into the simulations with a multiplier on the CBET gain factor. These measurements were performed on OMEGA and at the National Ignition Facility to access a wide range of plasma conditions, laser intensities, and laser beam geometries. The presence of the CBET gain multiplier required to match the data in all of the configurations tested suggests that additional physics effects, such as intensity variations caused by diffraction, polarization effects, or shortcomings of extending the 1-D Randall model to 3-D, should be explored to explain the differences in observed and predicted drive.« less

  5. Non-Traditional Transfer Student Attrition

    ERIC Educational Resources Information Center

    Monroe, Anne

    2006-01-01

    Current literature focuses on traditional student attrition and on transfer transition, but little information is available on the non-traditional transfer student experience. The following study explores the process of non-traditional transfer student attrition through an investigation that illustrates the importance of past student experiences,…

  6. University Technology Transfer Information Processing from the Attention Based View

    ERIC Educational Resources Information Center

    Hamilton, Clovia

    2015-01-01

    Between 2005 and 2011, there was no substantial growth in licenses executed by university technology transfer offices. Since the passage of the Bayh Dole Act of 1980, universities have owned technological inventions afforded by federal research funding. There are still university technology transfer offices that struggle with increasing their…

  7. Evaluating Technology Transfer and Diffusion.

    ERIC Educational Resources Information Center

    Bozeman, Barry; And Others

    1988-01-01

    Four articles discuss the evaluation of technology transfer and diffusion: (1) "Technology Transfer at the U.S. National Laboratories: A Framework for Evaluation"; (2) "Application of Social Psychological and Evaluation Research: Lessons from Energy Information Programs"; (3) "Technology and Knowledge Transfer in Energy R and D Laboratories: An…

  8. Global Access-controlled Transfer e-frame (GATe)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    2012-05-30

    Global Access-controlled Transfer e-frame (GATe) was designed to take advantage of the patterns that occur during an electronic record transfer process. The e-frame (or electronic framework or platform) is the foundation for developing secure information transfer to meet classified and unclassified business processes and is particularly useful when there is a need to share information with various entities in a controlled and secure environment. It can share, search, upload, download and retrieve sensitive information, as well as provides reporting capabilities.

  9. 12 CFR 205.10 - Preauthorized transfers.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    .... The person that obtains the authorization shall provide a copy to the consumer. (c) Consumer's right... shall inform the consumer of the right to receive notice of all varying transfers, but may give the... FUND TRANSFERS (REGULATION E) § 205.10 Preauthorized transfers. (a) Preauthorized transfers to consumer...

  10. Information transfer from DNA to peptide nucleic acids by template-directed syntheses

    NASA Technical Reports Server (NTRS)

    Schmidt, J. G.; Christensen, L.; Nielsen, P. E.; Orgel, L. E.; Bada, J. L. (Principal Investigator)

    1997-01-01

    Peptide nucleic acids (PNAs) are analogs of nucleic acids in which the ribose-phosphate backbone is replaced by a backbone held together by amide bonds. PNAs are interesting as models of alternative genetic systems because they form potentially informational base paired helical structures. Oligocytidylates have been shown to act as templates for formation of longer oligomers of G from PNA G2 dimers. In this paper we show that information can be transferred from DNA to PNA. DNA C4T2C4 is an efficient template for synthesis of PNA G4A2G4 using G2 and A2 units as substrates. The corresponding synthesis of PNA G4C2G4 on DNA C4G2C4 is less efficient. Incorporation of PNA T2 into PNA products on DNA C4A2C4 is the least efficient of the three reactions. These results, obtained using PNA dimers as substrates, parallel those obtained using monomeric activated nucleotides.

  11. A cloud-based workflow to quantify transcript-expression levels in public cancer compendia

    PubMed Central

    Tatlow, PJ; Piccolo, Stephen R.

    2016-01-01

    Public compendia of sequencing data are now measured in petabytes. Accordingly, it is infeasible for researchers to transfer these data to local computers. Recently, the National Cancer Institute began exploring opportunities to work with molecular data in cloud-computing environments. With this approach, it becomes possible for scientists to take their tools to the data and thereby avoid large data transfers. It also becomes feasible to scale computing resources to the needs of a given analysis. We quantified transcript-expression levels for 12,307 RNA-Sequencing samples from the Cancer Cell Line Encyclopedia and The Cancer Genome Atlas. We used two cloud-based configurations and examined the performance and cost profiles of each configuration. Using preemptible virtual machines, we processed the samples for as little as $0.09 (USD) per sample. As the samples were processed, we collected performance metrics, which helped us track the duration of each processing step and quantified computational resources used at different stages of sample processing. Although the computational demands of reference alignment and expression quantification have decreased considerably, there remains a critical need for researchers to optimize preprocessing steps. We have stored the software, scripts, and processed data in a publicly accessible repository (https://osf.io/gqrz9). PMID:27982081

  12. Multiscale Information Transfer in Functional Corticomuscular Coupling Estimation Following Stroke: A Pilot Study

    PubMed Central

    Chen, Xiaoling; Xie, Ping; Zhang, Yuanyuan; Chen, Yuling; Yang, Fangmei; Zhang, Litai; Li, Xiaoli

    2018-01-01

    Recently, functional corticomuscular coupling (FCMC) between the cortex and the contralateral muscle has been used to evaluate motor function after stroke. As we know, the motor-control system is a closed-loop system that is regulated by complex self-regulating and interactive mechanisms which operate in multiple spatial and temporal scales. Multiscale analysis can represent the inherent complexity. However, previous studies in FCMC for stroke patients mainly focused on the coupling strength in single-time scale, without considering the changes of the inherently directional and multiscale properties in sensorimotor systems. In this paper, a multiscale-causal model, named multiscale transfer entropy, was used to quantify the functional connection between electroencephalogram over the scalp and electromyogram from the flexor digitorum superficialis (FDS) recorded simultaneously during steady-state grip task in eight stroke patients and eight healthy controls. Our results showed that healthy controls exhibited higher coupling when the scale reached up to about 12, and the FCMC in descending direction was stronger at certain scales (1, 7, 12, and 14) than that in ascending direction. Further analysis showed these multi-time scale characteristics mainly focused on the beta1 band at scale 11 and beta2 band at scale 9, 11, 13, and 15. Compared to controls, the multiscale properties of the FCMC for stroke were changed, the strengths in both directions were reduced, and the gaps between the descending and ascending directions were disappeared over all scales. Further analysis in specific bands showed that the reduced FCMC mainly focused on the alpha2 at higher scale, beta1 and beta2 across almost the entire scales. This study about multi-scale confirms that the FCMC between the brain and muscles is capable of complex and directional characteristics, and these characteristics in functional connection for stroke are destroyed by the structural lesion in the brain that might

  13. Transfer Innovations Fund Updating Project. BC Council on Admissions and Transfer. Tourism Management Articulation

    ERIC Educational Resources Information Center

    British Columbia Council on Admissions and Transfer, 2010

    2010-01-01

    In 2008, a number of changes were identified that expanded the scope of the updating required for Block Transfer for tourism management as follows: a new core curriculum for diploma programs; the need for expanded information on diploma to diploma transfer; and, a growing need for an expanded system of transfer identified in Campus 2020…

  14. Quantifying resilience

    USGS Publications Warehouse

    Allen, Craig R.; Angeler, David G.

    2016-01-01

    Several frameworks to operationalize resilience have been proposed. A decade ago, a special feature focused on quantifying resilience was published in the journal Ecosystems (Carpenter, Westley & Turner 2005). The approach there was towards identifying surrogates of resilience, but few of the papers proposed quantifiable metrics. Consequently, many ecological resilience frameworks remain vague and difficult to quantify, a problem that this special feature aims to address. However, considerable progress has been made during the last decade (e.g. Pope, Allen & Angeler 2014). Although some argue that resilience is best kept as an unquantifiable, vague concept (Quinlan et al. 2016), to be useful for managers, there must be concrete guidance regarding how and what to manage and how to measure success (Garmestani, Allen & Benson 2013; Spears et al. 2015). Ideas such as ‘resilience thinking’ have utility in helping stakeholders conceptualize their systems, but provide little guidance on how to make resilience useful for ecosystem management, other than suggesting an ambiguous, Goldilocks approach of being just right (e.g. diverse, but not too diverse; connected, but not too connected). Here, we clarify some prominent resilience terms and concepts, introduce and synthesize the papers in this special feature on quantifying resilience and identify core unanswered questions related to resilience.

  15. Quantifying uncertainty in Bayesian calibrated animal-to-human PBPK models with informative prior distributions

    EPA Science Inventory

    Understanding and quantifying the uncertainty of model parameters and predictions has gained more interest in recent years with the increased use of computational models in chemical risk assessment. Fully characterizing the uncertainty in risk metrics derived from linked quantita...

  16. NREL, Johns Hopkins SAIS Develop Method to Quantify Life Cycle Land Use of

    Science.gov Websites

    Life Cycle Land Use of Electricity from Natural Gas News Release: NREL, Johns Hopkins SAIS Develop Method to Quantify Life Cycle Land Use of Electricity from Natural Gas October 2, 2017 A case study of time provides quantifiable information on the life cycle land use of generating electricity from

  17. Effect of air bubble localization after transfer on embryo transfer outcomes.

    PubMed

    Tiras, Bulent; Korucuoglu, Umit; Polat, Mehtap; Saltik, Ayse; Zeyneloglu, Hulusi Bulent; Yarali, Hakan

    2012-09-01

    Our study aimed to provide information about the effects of air bubble localization after transfer on embryo transfer outcomes. Retrospective analysis of 7489 ultrasound-guided embryo transfers. Group 1 included 6631 embryo transfers in which no movement of the air bubbles was observed after transfer. Group 2 consisted of 407 embryo transfers in which the air bubbles moved towards the uterine fundus spontaneously, a little time after transfer. Group 3 included 370 embryo transfers in which the air bubbles moved towards the uterine fundus with ejection, immediately after transfer. Group 4 consisted of 81 embryo transfers in which the air bubbles moved towards the cervical canal. The four patient groups were different from one another with respect to positive pregnancy tests. Post hoc test revealed that this difference was between group 4 and other groups. An initial finding of our study was significantly decreased positive pregnancy test rates and clinical pregnancy rates with air bubbles moving towards the cervical canal after transfer. Although air bubbles moving towards the uterine fundus with ejection were associated with higher pregnancy rates, higher miscarriage rates and similar live birth rates were observed compared to air bubbles remaining stable after transfer. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  18. Mountain torrents: Quantifying vulnerability and assessing uncertainties

    PubMed Central

    Totschnig, Reinhold; Fuchs, Sven

    2013-01-01

    Vulnerability assessment for elements at risk is an important component in the framework of risk assessment. The vulnerability of buildings affected by torrent processes can be quantified by vulnerability functions that express a mathematical relationship between the degree of loss of individual elements at risk and the intensity of the impacting process. Based on data from the Austrian Alps, we extended a vulnerability curve for residential buildings affected by fluvial sediment transport processes to other torrent processes and other building types. With respect to this goal to merge different data based on different processes and building types, several statistical tests were conducted. The calculation of vulnerability functions was based on a nonlinear regression approach applying cumulative distribution functions. The results suggest that there is no need to distinguish between different sediment-laden torrent processes when assessing vulnerability of residential buildings towards torrent processes. The final vulnerability functions were further validated with data from the Italian Alps and different vulnerability functions presented in the literature. This comparison showed the wider applicability of the derived vulnerability functions. The uncertainty inherent to regression functions was quantified by the calculation of confidence bands. The derived vulnerability functions may be applied within the framework of risk management for mountain hazards within the European Alps. The method is transferable to other mountain regions if the input data needed are available. PMID:27087696

  19. Relative significance of heat transfer processes to quantify tradeoffs between complexity and accuracy of energy simulations with a building energy use patterns classification

    NASA Astrophysics Data System (ADS)

    Heidarinejad, Mohammad

    This dissertation develops rapid and accurate building energy simulations based on a building classification that identifies and focuses modeling efforts on most significant heat transfer processes. The building classification identifies energy use patterns and their contributing parameters for a portfolio of buildings. The dissertation hypothesis is "Building classification can provide minimal required inputs for rapid and accurate energy simulations for a large number of buildings". The critical literature review indicated there is lack of studies to (1) Consider synoptic point of view rather than the case study approach, (2) Analyze influence of different granularities of energy use, (3) Identify key variables based on the heat transfer processes, and (4) Automate the procedure to quantify model complexity with accuracy. Therefore, three dissertation objectives are designed to test out the dissertation hypothesis: (1) Develop different classes of buildings based on their energy use patterns, (2) Develop different building energy simulation approaches for the identified classes of buildings to quantify tradeoffs between model accuracy and complexity, (3) Demonstrate building simulation approaches for case studies. Penn State's and Harvard's campus buildings as well as high performance LEED NC office buildings are test beds for this study to develop different classes of buildings. The campus buildings include detailed chilled water, electricity, and steam data, enabling to classify buildings into externally-load, internally-load, or mixed-load dominated. The energy use of the internally-load buildings is primarily a function of the internal loads and their schedules. Externally-load dominated buildings tend to have an energy use pattern that is a function of building construction materials and outdoor weather conditions. However, most of the commercial medium-sized office buildings have a mixed-load pattern, meaning the HVAC system and operation schedule dictate

  20. Topological Quantum Buses: Coherent Quantum Information Transfer between Topological and Conventional Qubits

    NASA Astrophysics Data System (ADS)

    Bonderson, Parsa; Lutchyn, Roman M.

    2011-04-01

    We propose computing bus devices that enable quantum information to be coherently transferred between topological and conventional qubits. We describe a concrete realization of such a topological quantum bus acting between a topological qubit in a Majorana wire network and a conventional semiconductor double quantum dot qubit. Specifically, this device measures the joint (fermion) parity of these two different qubits by using the Aharonov-Casher effect in conjunction with an ancilliary superconducting flux qubit that facilitates the measurement. Such a parity measurement, together with the ability to apply Hadamard gates to the two qubits, allows one to produce states in which the topological and conventional qubits are maximally entangled and to teleport quantum states between the topological and conventional quantum systems.

  1. Topological quantum buses: coherent quantum information transfer between topological and conventional qubits.

    PubMed

    Bonderson, Parsa; Lutchyn, Roman M

    2011-04-01

    We propose computing bus devices that enable quantum information to be coherently transferred between topological and conventional qubits. We describe a concrete realization of such a topological quantum bus acting between a topological qubit in a Majorana wire network and a conventional semiconductor double quantum dot qubit. Specifically, this device measures the joint (fermion) parity of these two different qubits by using the Aharonov-Casher effect in conjunction with an ancilliary superconducting flux qubit that facilitates the measurement. Such a parity measurement, together with the ability to apply Hadamard gates to the two qubits, allows one to produce states in which the topological and conventional qubits are maximally entangled and to teleport quantum states between the topological and conventional quantum systems. © 2011 American Physical Society

  2. Replica symmetric evaluation of the information transfer in a two-layer network in the presence of continuous and discrete stimuli.

    PubMed

    Del Prete, Valeria; Treves, Alessandro

    2002-04-01

    In a previous paper we have evaluated analytically the mutual information between the firing rates of N independent units and a set of multidimensional continuous and discrete stimuli, for a finite population size and in the limit of large noise. Here, we extend the analysis to the case of two interconnected populations, where input units activate output ones via Gaussian weights and a threshold linear transfer function. We evaluate the information carried by a population of M output units, again about continuous and discrete correlates. The mutual information is evaluated solving saddle-point equations under the assumption of replica symmetry, a method that, by taking into account only the term linear in N of the input information, is equivalent to assuming the noise to be large. Within this limitation, we analyze the dependence of the information on the ratio M/N, on the selectivity of the input units and on the level of the output noise. We show analytically, and confirm numerically, that in the limit of a linear transfer function and of a small ratio between output and input noise, the output information approaches asymptotically the information carried in input. Finally, we show that the information loss in output does not depend much on the structure of the stimulus, whether purely continuous, purely discrete or mixed, but only on the position of the threshold nonlinearity, and on the ratio between input and output noise.

  3. Towards simulating and quantifying the light-cone EoR 21-cm signal

    NASA Astrophysics Data System (ADS)

    Mondal, Rajesh; Bharadwaj, Somnath; Datta, Kanan K.

    2018-02-01

    The light-cone (LC) effect causes the Epoch of Reionization (EoR) 21-cm signal T_b (\\hat{n}, ν ) to evolve significantly along the line-of-sight (LoS) direction ν. In the first part of this paper, we present a method to properly incorporate the LC effect in simulations of the EoR 21-cm signal that includes peculiar velocities. Subsequently, we discuss how to quantify the second-order statistics of the EoR 21-cm signal in the presence of the LC effect. We demonstrate that the 3D power spectrum P(k) fails to quantify the entire information because it assumes the signal to be ergodic and periodic, whereas the LC effect breaks these conditions along the LoS. Considering a LC simulation centred at redshift 8 where the mean neutral fraction drops from 0.65 to 0.35 across the box, we find that P(k) misses out ˜ 40 per cent of the information at the two ends of the 17.41 MHz simulation bandwidth. The multifrequency angular power spectrum (MAPS) C_{ℓ}(ν_1,ν_2) quantifies the statistical properties of T_b (\\hat{n}, ν ) without assuming the signal to be ergodic and periodic along the LoS. We expect this to quantify the entire statistical information of the EoR 21-cm signal. We apply MAPS to our LC simulation and present preliminary results for the EoR 21-cm signal.

  4. Spatial transferability of habitat suitability models of Nephrops norvegicus among fished areas in the Northeast Atlantic: sufficiently stable for marine resource conservation?

    PubMed

    Lauria, Valentina; Power, Anne Marie; Lordan, Colm; Weetman, Adrian; Johnson, Mark P

    2015-01-01

    Knowledge of the spatial distribution and habitat associations of species in relation to the environment is essential for their management and conservation. Habitat suitability models are useful in quantifying species-environment relationships and predicting species distribution patterns. Little is known, however, about the stability and performance of habitat suitability models when projected into new areas (spatial transferability) and how this can inform resource management. The aims of this study were to model habitat suitability of Norway lobster (Nephrops norvegicus) in five fished areas of the Northeast Atlantic (Aran ground, Irish Sea, Celtic Sea, Scotland Inshore and Fladen ground), and to test for spatial transferability of habitat models among multiple regions. Nephrops burrow density was modelled using generalised additive models (GAMs) with predictors selected from four environmental variables (depth, slope, sediment and rugosity). Models were evaluated and tested for spatial transferability among areas. The optimum models (lowest AICc) for different areas always included depth and sediment as predictors. Burrow densities were generally greater at depth and in finer sediments, but relationships for individual areas were sometimes more complex. Aside from an inclusion of depth and sediment, the optimum models differed between fished areas. When it came to tests of spatial transferability, however, most of the models were able to predict Nephrops density in other areas. Furthermore, transferability was not dependent on use of the optimum models since competing models were also able to achieve a similar level of transferability to new areas. A degree of decoupling between model 'fitting' performance and spatial transferability supports the use of simpler models when extrapolating habitat suitability maps to different areas. Differences in the form and performance of models from different areas may supply further information on the processes shaping

  5. Isolating and quantifying cross-beam energy transfer in direct-drive implosions on OMEGA and the National Ignition Facility

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Davis, A. K.; Cao, D.; Michel, D. T.

    The angularly-resolved mass ablation rates and ablation front trajectories for Si-coated CH targets were measured in direct-drive inertial confinement fusion experiments to quantify crossbeam energy transfer (CBET) while constraining the hydrodynamic coupling. A polar-direct-drive laser configuration was used, where the equatorial laser beams were dropped from a symmetric direct-drive configuration to suppress CBET at the pole, while allowing it to persist at the equator. The combination of low- and high-CBET conditions in the same implosion allowed the effects of CBET on the ablation rate and ablation pressure to be decoupled from the other physics effects that influence laser-coupling. Hydrodynamic simulationsmore » performed without CBET reproduced the measured ablation rate and ablation front trajectory at the pole of the target, verifying that the other laser-coupling physics effects are well-modeled when CBET effects are negligible. The simulated mass ablation rates and ablation front trajectories were in excellent agreement with the measurements at all angles when a CBET model based on Randall’s equations [C. J. Randall et al., Phys. Fluids 24, 1474 (1981)] was included into the simulations with an optimized multiplier on the CBET gain factor. These measurements were performed on both OMEGA and the National Ignition Facility to access a wide range of plasma conditions, laser intensities, and laser beam geometries. Furthermore, the presence of the CBET gain multiplier required to match the data in all of the configurations tested suggests that additional physics effects, such as intensity variations due to diffraction, shortcomings of extending the 1-D Randall model to 3-D, or polarization effects, should be explored to explain the differences in observed and predicted drive.« less

  6. Isolating and quantifying cross-beam energy transfer in direct-drive implosions on OMEGA and the National Ignition Facility

    DOE PAGES

    Davis, A. K.; Cao, D.; Michel, D. T.; ...

    2016-04-20

    The angularly-resolved mass ablation rates and ablation front trajectories for Si-coated CH targets were measured in direct-drive inertial confinement fusion experiments to quantify crossbeam energy transfer (CBET) while constraining the hydrodynamic coupling. A polar-direct-drive laser configuration was used, where the equatorial laser beams were dropped from a symmetric direct-drive configuration to suppress CBET at the pole, while allowing it to persist at the equator. The combination of low- and high-CBET conditions in the same implosion allowed the effects of CBET on the ablation rate and ablation pressure to be decoupled from the other physics effects that influence laser-coupling. Hydrodynamic simulationsmore » performed without CBET reproduced the measured ablation rate and ablation front trajectory at the pole of the target, verifying that the other laser-coupling physics effects are well-modeled when CBET effects are negligible. The simulated mass ablation rates and ablation front trajectories were in excellent agreement with the measurements at all angles when a CBET model based on Randall’s equations [C. J. Randall et al., Phys. Fluids 24, 1474 (1981)] was included into the simulations with an optimized multiplier on the CBET gain factor. These measurements were performed on both OMEGA and the National Ignition Facility to access a wide range of plasma conditions, laser intensities, and laser beam geometries. Furthermore, the presence of the CBET gain multiplier required to match the data in all of the configurations tested suggests that additional physics effects, such as intensity variations due to diffraction, shortcomings of extending the 1-D Randall model to 3-D, or polarization effects, should be explored to explain the differences in observed and predicted drive.« less

  7. Quantifying the variability of financial disclosure information reported by authors presenting at annual spine conferences.

    PubMed

    Ju, Brian L; Miller, Christopher P; Whang, Peter G; Grauer, Jonathan N

    2011-01-01

    In recent years, greater attention has been directed toward determining how potential financial conflicts of interest may affect the integrity of biomedical research. To address this issue, various disclosure policies have been adopted in an attempt to increase the transparency of this process. However, the consistency of such reporting among spine surgeons remains unknown. This study quantifies the variability in the self-reported disclosures of individual authors presenting at multiple spine conferences during the same year. The author disclosure information published for the 2008 North American Spine Society (NASS), Cervical Spine Research Society (CSRS), and Scoliosis Research Society (SRS), conferences were compiled into a database. We evaluated the disclosure policy for each society and compared the disclosure listings of authors who presented at more than one of these meetings. Disclosure records were available for 1,231 authors at NASS, 550 at CSRS, and 642 at SRS. Of these individuals, 278 (NASS), 129 (CSRS), and 181 (SRS) presented at one of the other conferences and 40 presented at all three conferences. North American Spine Society and CSRS required disclosure of all financial relationships, whereas SRS only requested disclosures pertinent to authors' presentations. Of the 153 authors who presented at the NASS and CSRS meetings, 51% exhibited discrepancies in their disclosure information. In contrast, only 9% of the 205 individuals whose data was listed at both the NASS and SRS conferences demonstrated irregularities. Similarly, 18% of the 56 authors who had provided information to both CSRS and SRS were inconsistent in their reporting. These findings emphasize the significant variability that currently exists in the reporting of financial conflicts of interest by authors who presented at three major spine conferences within the past year. We believe these discrepancies are likely because of confusion regarding what relationships should be acknowledged

  8. A mass-balance model to separate and quantify colloidal and solute redistributions in soil

    USGS Publications Warehouse

    Bern, C.R.; Chadwick, O.A.; Hartshorn, A.S.; Khomo, L.M.; Chorover, J.

    2011-01-01

    Studies of weathering and pedogenesis have long used calculations based upon low solubility index elements to determine mass gains and losses in open systems. One of the questions currently unanswered in these settings is the degree to which mass is transferred in solution (solutes) versus suspension (colloids). Here we show that differential mobility of the low solubility, high field strength (HFS) elements Ti and Zr can trace colloidal redistribution, and we present a model for distinguishing between mass transfer in suspension and solution. The model is tested on a well-differentiated granitic catena located in Kruger National Park, South Africa. Ti and Zr ratios from parent material, soil and colloidal material are substituted into a mixing equation to quantify colloidal movement. The results show zones of both colloid removal and augmentation along the catena. Colloidal losses of 110kgm-2 (-5% relative to parent material) are calculated for one eluviated soil profile. A downslope illuviated profile has gained 169kgm-2 (10%) colloidal material. Elemental losses by mobilization in true solution are ubiquitous across the catena, even in zones of colloidal accumulation, and range from 1418kgm-2 (-46%) for an eluviated profile to 195kgm-2 (-23%) at the bottom of the catena. Quantification of simultaneous mass transfers in solution and suspension provide greater specificity on processes within soils and across hillslopes. Additionally, because colloids include both HFS and other elements, the ability to quantify their redistribution has implications for standard calculations of soil mass balances using such index elements. ?? 2011.

  9. Acute Sleep Deprivation Induces a Local Brain Transfer Information Increase in the Frontal Cortex in a Widespread Decrease Context.

    PubMed

    Alonso, Joan F; Romero, Sergio; Mañanas, Miguel A; Alcalá, Marta; Antonijoan, Rosa M; Giménez, Sandra

    2016-04-14

    Sleep deprivation (SD) has adverse effects on mental and physical health, affecting the cognitive abilities and emotional states. Specifically, cognitive functions and alertness are known to decrease after SD. The aim of this work was to identify the directional information transfer after SD on scalp EEG signals using transfer entropy (TE). Using a robust methodology based on EEG recordings of 18 volunteers deprived from sleep for 36 h, TE and spectral analysis were performed to characterize EEG data acquired every 2 h. Correlation between connectivity measures and subjective somnolence was assessed. In general, TE showed medium- and long-range significant decreases originated at the occipital areas and directed towards different regions, which could be interpreted as the transfer of predictive information from parieto-occipital activity to the rest of the head. Simultaneously, short-range increases were obtained for the frontal areas, following a consistent and robust time course with significant maps after 20 h of sleep deprivation. Changes during sleep deprivation in brain network were measured effectively by TE, which showed increased local connectivity and diminished global integration. TE is an objective measure that could be used as a potential measure of sleep pressure and somnolence with the additional property of directed relationships.

  10. Information Transfer Case Studies in Foreign Transportation Literature

    DOT National Transportation Integrated Search

    1983-09-01

    An assessment of the effectiveness of the transfer of foreign literature to U.S. transportation professionals has been conducted. The methodology involved a series of case studies concerning (1) distribution of the report on a major German Federal Re...

  11. Quantifying Contextual Interference and Its Effect on Skill Transfer in Skilled Youth Tennis Players

    PubMed Central

    Buszard, Tim; Reid, Machar; Krause, Lyndon; Kovalchik, Stephanie; Farrow, Damian

    2017-01-01

    The contextual interference effect is a well-established motor learning phenomenon. Most of the contextual interference effect literature has addressed simple skills, while less is known about the role of contextual interference in complex sport skill practice, particularly with respect to skilled performers. The purpose of this study was to assess contextual interference when practicing the tennis serve. Study 1 evaluated tennis serve practice of nine skilled youth tennis players using a novel statistical metric developed specifically to measure between-skill and within-skill variability as sources of contextual interference. This metric highlighted that skilled tennis players typically engaged in serve practice that featured low contextual interference. In Study 2, 16 skilled youth tennis players participated in 10 practice sessions that aimed to improve serving “down the T.” Participants were stratified into a low contextual interference practice group (Low CI) and a moderate contextual interference practice group (Moderate CI). Pre- and post-tests were conducted 1 week before and 1 week after the practice period. Testing involved a skill test, which assessed serving performance in a closed setting, and a transfer test, which assessed serving performance in a match-play setting. No significant contextual interference differences were observed with respect to practice performance. However, analysis of pre- and post-test serve performance revealed significant Group × Time interactions. The Moderate CI group showed no change in serving performance (service displacement from the T) from pre- to post-test in the skill test, but did display improvements in the transfer test. Conversely, the Low CI group improved serving performance (service displacement from the T) in the skill test but not the transfer test. Results suggest that the typical contextual interference effect is less clear when practicing a complex motor skill, at least with the tennis serve skill

  12. The Cost of Concreteness: The Effect of Nonessential Information on Analogical Transfer

    ERIC Educational Resources Information Center

    Kaminski, Jennifer A.; Sloutsky, Vladimir M.; Heckler, Andrew F.

    2013-01-01

    Most theories of analogical transfer focus on similarities between the learning and transfer domains, where transfer is more likely between domains that share common surface features, similar elements, or common interpretations of structure. We suggest that characteristics of the learning instantiation alone can give rise to different levels of…

  13. Using transfer functions to quantify El Niño Southern Oscillation dynamics in data and models.

    PubMed

    MacMartin, Douglas G; Tziperman, Eli

    2014-09-08

    Transfer function tools commonly used in engineering control analysis can be used to better understand the dynamics of El Niño Southern Oscillation (ENSO), compare data with models and identify systematic model errors. The transfer function describes the frequency-dependent input-output relationship between any pair of causally related variables, and can be estimated from time series. This can be used first to assess whether the underlying relationship is or is not frequency dependent, and if so, to diagnose the underlying differential equations that relate the variables, and hence describe the dynamics of individual subsystem processes relevant to ENSO. Estimating process parameters allows the identification of compensating model errors that may lead to a seemingly realistic simulation in spite of incorrect model physics. This tool is applied here to the TAO array ocean data, the GFDL-CM2.1 and CCSM4 general circulation models, and to the Cane-Zebiak ENSO model. The delayed oscillator description is used to motivate a few relevant processes involved in the dynamics, although any other ENSO mechanism could be used instead. We identify several differences in the processes between the models and data that may be useful for model improvement. The transfer function methodology is also useful in understanding the dynamics and evaluating models of other climate processes.

  14. Polymeric film application for phase change heat transfer

    NASA Astrophysics Data System (ADS)

    Bart, Hans-Jörg; Dreiser, Christian

    2018-06-01

    The paper gives a concise review on polymer film heat exchangers (PFHX) with a focus on polyether ether ketone (PEEK) foil as heat transfer element, mechanically supported by a grid structure. In order to promote PFHX applications, heat transfer performance and wetting behavior are studied in detail. Surface modifications to improve wetting are discussed and correlations are presented for critical Reynolds numbers to sustain a stable liquid film. Scaling phenomena related to surface properties and easily adaptable cleaning-in-place (CIP) procedures are further content. The contribution of the foil thickness and material selection on thermal performance is quantified and a correlation for enhanced aqueous film heat transfer for the grid supported PFHX is given. The basic research results and the design criteria enable early stage material selection and conceptual apparatus design.

  15. Polymeric film application for phase change heat transfer

    NASA Astrophysics Data System (ADS)

    Bart, Hans-Jörg; Dreiser, Christian

    2018-01-01

    The paper gives a concise review on polymer film heat exchangers (PFHX) with a focus on polyether ether ketone (PEEK) foil as heat transfer element, mechanically supported by a grid structure. In order to promote PFHX applications, heat transfer performance and wetting behavior are studied in detail. Surface modifications to improve wetting are discussed and correlations are presented for critical Reynolds numbers to sustain a stable liquid film. Scaling phenomena related to surface properties and easily adaptable cleaning-in-place (CIP) procedures are further content. The contribution of the foil thickness and material selection on thermal performance is quantified and a correlation for enhanced aqueous film heat transfer for the grid supported PFHX is given. The basic research results and the design criteria enable early stage material selection and conceptual apparatus design.

  16. Virtual versus real water transfers within China.

    PubMed

    Ma, Jing; Hoekstra, Arjen Y; Wang, Hao; Chapagain, Ashok K; Wang, Dangxian

    2006-05-29

    North China faces severe water scarcity--more than 40% of the annual renewable water resources are abstracted for human use. Nevertheless, nearly 10% of the water used in agriculture is employed in producing food exported to south China. To compensate for this 'virtual water flow' and to reduce water scarcity in the north, the huge south-north Water Transfer Project is currently being implemented. This paradox--the transfer of huge volumes of water from the water-rich south to the water-poor north versus transfer of substantial volumes of food from the food-sufficient north to the food-deficit south--is receiving increased attention, but the research in this field has not yet reached further than rough estimation and qualitative description. The aim of this paper is to review and quantify the volumes of virtual water flows between the regions in China and to put them in the context of water availability per region. The analysis shows that north China annually exports about 52 billion m3 of water in virtual form to south China, which is more than the maximum proposed water transfer volume along the three routes of the Water Transfer Project from south to north.

  17. Quantifying hydrologic connectivity with measures from the brain neurosciences - a feasibility study

    NASA Astrophysics Data System (ADS)

    Rinderer, Michael; Ali, Genevieve; Larsen, Laurel

    2017-04-01

    While the concept of connectivity is increasingly applied in hydrology and ecology, little agreement exists on its definition and quantification approaches. In contrast, the neurosciences have developed a systematic conceptualization of connectivity and methods to quantify it. In particular, neuroscientists make a clear distinction between: 1) structural connectivity, which is determined by the anatomy of the brain neural network, 2) functional connectivity, that is based on statistical dependencies between neural signals, and 3) effective connectivity, that allows to infer causal relations based on the assumption that "true" interactions occur with a certain time delay. In a similar vein, in hydrology, structural connectivity can be defined as the physical adjacency of landscape elements that are seen as a prerequisite of material transfer, while functional or process connectivity would rather describe interactions or causal relations between spatial adjacency characteristics and temporally varying factors. While hydrologists have suggested methods to derive structural connectivity (SC), the quantification of functional (FC) or effective connectivity (EC) has remained elusive. The goal of the current study was therefore to apply timeseries analysis methods from brain neuroscience to quantify EC and FC among groundwater (n = 34) and stream discharge (n = 1) monitoring sites in a 20-ha Swiss catchment where topography is assumed to be a major driver of connectivity. SC was assessed through influence maps that quantify the percentage of flow from an upslope site to a downslope site by applying a multiple flow direction algorithm. FC was assessed by cross-correlation, total and partial mutual information while EC was quantified via total and partial entropy, Granger causality and a phase slope index. Our results showed that many structural connections were also expressed as functional or effective connections, which is reasonable in a catchment with shallow perched

  18. Information Forests

    DTIC Science & Technology

    2014-01-01

    Classification confidence, or informative content of the subsets, is quantified by the Information Divergence. Our approach relates to active learning , semi-supervised learning, mixed generative/discriminative learning.

  19. 17 CFR 249.619 - Form TA-Y2K, information required of transfer agents pursuant to section 17 of the Securities...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Form TA-Y2K, information... Certain Exchange Members, Brokers, and Dealers § 249.619 Form TA-Y2K, information required of transfer... affecting Form TA-Y2K, see the List of CFR Sections Affected, which appears in the Finding Aids section of...

  20. Face Adaptation Effects: Reviewing the Impact of Adapting Information, Time, and Transfer

    PubMed Central

    Strobach, Tilo; Carbon, Claus-Christian

    2013-01-01

    The ability to adapt is essential to live and survive in an ever-changing environment such as the human ecosystem. Here we review the literature on adaptation effects of face stimuli to give an overview of existing findings in this area, highlight gaps in its research literature, initiate new directions in face adaptation research, and help to design future adaptation studies. Furthermore, this review should lead to better understanding of the processing characteristics as well as the mental representations of face-relevant information. The review systematizes studies at a behavioral level in respect of a framework which includes three dimensions representing the major characteristics of studies in this field of research. These dimensions comprise (1) the specificity of adapting face information, e.g., identity, gender, or age aspects of the material to be adapted to (2) aspects of timing (e.g., the sustainability of adaptation effects) and (3) transfer relations between face images presented during adaptation and adaptation tests (e.g., images of the same or different identities). The review concludes with options for how to combine findings across different dimensions to demonstrate the relevance of our framework for future studies. PMID:23760550

  1. Information Transfer and the Hospital Discharge Summary: National Primary Care Provider Perspectives of Challenges and Opportunities.

    PubMed

    Robelia, Paul M; Kashiwagi, Deanne T; Jenkins, Sarah M; Newman, James S; Sorita, Atsushi

    2017-01-01

    The hospital discharge summary (HDS) serves as a critical method of patient information transfer between hospitalist and primary care provider (PCP). This study was designed to increase our understanding of PCP preferences for, and perceived deficiencies in, the discharge summary. We designed a mail survey that was sent to a random sample of 800 American Academy of Family Physicians members nationally. The survey response rate was 59%. We analyzed the availability of summaries at hospital followup, whether all desired information was contained in the summary and whether certain specific items were completed. Provider subgroup analysis was performed. The strongest predictor of discharge summary availability at posthospital followup is direct access to inpatient data. Respondents (27.5%) had a summary available 0% to 40% of the time, 41.4% noted availability 41% to 80% of the time and 31.1% >80% of the time; if a provider had access to inpatient data they tended to have a discharge summary available to them ( P < .0001). Providers also described significant content deficits: 26.5% of providers noted the summary contained all information needed 0% to 40% of the time, 48.5% of providers noted this 41% to 80% of the time and only 25% >80% of the time. Specific summary items considered "very important" by providers included medication list (94% of respondents), diagnosis list (89%), and treatment provided (87%). Opportunities remain in timely delivery of a complete HDS to the PCP. Further multifaceted practice redesign should be directed at optimizing this critical information transfer tool, potentially encompassing electronic medical record utilization and specific training for clinicians preparing summaries. Initial efforts should focus on ensuring availability of a complete summary (containing items deemed important by PCPs including medication list, diagnosis list, and treatment provided) at the posthospital follow-up visit. © Copyright 2017 by the American Board of

  2. Developing SoilML as a global standard for the collation and transfer of soil data and information.

    NASA Astrophysics Data System (ADS)

    Montanarella, Luca; Wilson, Peter; Cox, Simon; McBratney, Alex; Ahamed, Sonya; McMillan, Bob; Jacquier, David; Fortner, Jim

    2010-05-01

    There is an increasing need to collect, collate and share soil data and information within countries, across regions and globally. Timely access to consistent and authoritative data and information is critical to issues related to food production, climate change, water management, energy production and biodiversityl. Soil data and information is managed by numerous agencies and organisations using a plethora of processes, scales and standards. A number of national and international activities and projects are currently dealing with the issues associated with collation of disparate data sets. Standards are being developed for data storage, transfer and collation like, for example, in the GobalSoilMap.net project, e-SOTER and the EU Inspire GS-SOIL. Individually these will not provide a single internationally recognised and adopted standard for soil data and information exchange. A recent GlobalSoilMap.net meeting held in Wageningen, The Netherlands, discussed the needs of a harmonized information model for collation of a global 90 metre grid of key soil attributes (organic carbon, soil texture, pH, depth to bedrock/impeding layer, and predictions of bulk density and available water capacity) at six specified depth increments. The meeting considered a number of existing data base implementations (such as ASRIS, NASIS, WISE, SOTER) as well as emerging abstract information models that are being expressed in UML (such as e-SOTER). It examined related information models, such as GeoSciML and the lessons learnt in developing and implementing such community agreed models, features and vocabularies. There is a need to develop a global soil information standard, to be called SoilML, that would allow access and use of data across a broad range of international initiatives (such as GEOSS and INSPIRE) as well as supporting national, regional and local data interoperability and integration. The meeting agreed to adopt the interoperability approaches of formalising the

  3. Quantifying the evolution of flow boiling bubbles by statistical testing and image analysis: toward a general model.

    PubMed

    Xiao, Qingtai; Xu, Jianxin; Wang, Hua

    2016-08-16

    A new index, the estimate of the error variance, which can be used to quantify the evolution of the flow patterns when multiphase components or tracers are difficultly distinguishable, was proposed. The homogeneity degree of the luminance space distribution behind the viewing windows in the direct contact boiling heat transfer process was explored. With image analysis and a linear statistical model, the F-test of the statistical analysis was used to test whether the light was uniform, and a non-linear method was used to determine the direction and position of a fixed source light. The experimental results showed that the inflection point of the new index was approximately equal to the mixing time. The new index has been popularized and applied to a multiphase macro mixing process by top blowing in a stirred tank. Moreover, a general quantifying model was introduced for demonstrating the relationship between the flow patterns of the bubble swarms and heat transfer. The results can be applied to investigate other mixing processes that are very difficult to recognize the target.

  4. Quantifying the evolution of flow boiling bubbles by statistical testing and image analysis: toward a general model

    PubMed Central

    Xiao, Qingtai; Xu, Jianxin; Wang, Hua

    2016-01-01

    A new index, the estimate of the error variance, which can be used to quantify the evolution of the flow patterns when multiphase components or tracers are difficultly distinguishable, was proposed. The homogeneity degree of the luminance space distribution behind the viewing windows in the direct contact boiling heat transfer process was explored. With image analysis and a linear statistical model, the F-test of the statistical analysis was used to test whether the light was uniform, and a non-linear method was used to determine the direction and position of a fixed source light. The experimental results showed that the inflection point of the new index was approximately equal to the mixing time. The new index has been popularized and applied to a multiphase macro mixing process by top blowing in a stirred tank. Moreover, a general quantifying model was introduced for demonstrating the relationship between the flow patterns of the bubble swarms and heat transfer. The results can be applied to investigate other mixing processes that are very difficult to recognize the target. PMID:27527065

  5. Clinical methods to quantify trunk mobility in an elite male surfing population.

    PubMed

    Furness, James; Climstein, Mike; Sheppard, Jeremy M; Abbott, Allan; Hing, Wayne

    2016-05-01

    Thoracic mobility in the sagittal and horizontal planes are key requirements in the sport of surfing; however to date the normal values of these movements have not yet been quantified in a surfing population. To develop a reliable method to quantify thoracic mobility in the sagittal plane; to assess the reliability of an existing thoracic rotation method, and quantify thoracic mobility in an elite male surfing population. Clinical Measurement, reliability and comparative study. A total of 30 subjects were used to determine the reliability component. 15 elite surfers were used as part of a comparative analysis with age and gender matched controls. Intraclass correlation coefficient values ranged between 0.95-0.99 (95% CI; 0.89-0.99) for both thoracic methods. The elite surfing group had significantly (p ≤ 0.05) greater rotation than the comparative group (mean rotation 63.57° versus 40.80°, respectively). This study has illustrated reliable methods to assess the thoracic spine in the sagittal plane and thoracic rotation. It has also quantified ROM in a surfing cohort; identifying thoracic rotation as a key movement. This information may provide clinicians, coaches and athletic trainers with imperative information regarding the importance of maintaining adequate thoracic rotation. Copyright © 2015 Elsevier Ltd. All rights reserved.

  6. Evaluating knowledge transfer practices among construction organization in Malaysia

    NASA Astrophysics Data System (ADS)

    Zaidi, Mohd Azian; Baharuddin, Mohd Nurfaisal; Bahardin, Nur Fadhilah; Yasin, Mohd Fadzil Mat; Nawi, Mohd Nasrun Mohd; Deraman, Rafikullah

    2016-08-01

    The aims of this paper is to identify a key dimension of knowledge transfer component to improve construction organization performance. It investigates the effectiveness of present knowledge transfer practices currently adopted by the Malaysian construction organizations and examines the relationship between knowledge transfer factors and organizational factors. A survey among 151 respondents including a different contractor registration grade was employed for the study. The survey shows that a seven-teen (17) factors known as creating shared awareness for information sharing, communication, personal skills,individual attitude,training, organizational culture, information technology,motivation, monitoring and supervision, service quality,information accessibility, information supply, socialization process,knowledge tools, coaching and monitoring, staff briefing and information sharing were identify as a key dimension for knowledge transfer success. This finding suggest that through improvement of each factor, the recognition of the whole strategic knowledge transfer process can be increase thus helping to strengthen the Malaysian construction organization for competitive advantages.

  7. Information handoff and outcomes of critically ill patients transferred between hospitals

    PubMed Central

    Usher, Michael G.; Fanning, Christine; Wu, Di; Muglia, Christine; Balonze, Karen; Kim, Deborah; Parikh, Amay; Herrigel, Dana

    2016-01-01

    Purpose Patients transferred between hospitals are at high risk of adverse events and mortality. This study aims to identify which components of the transfer handoff process are important predictors of adverse events and mortality. Materials and Methods We conducted a retrospective, observational study of 335 consecutive patient transfers to three ICUs at an academic tertiary referral center. We assessed the relationship between handoff documentation completeness and patient outcomes. The primary outcome was in-hospital mortality. Secondary outcomes included adverse events, duplication of labor, disposition error, and length of stay. Results Transfer documentation was frequently absent with overall completeness of 58.3%. Adverse events occurred in 42% of patients within 24 hours of arrival, with an overall in-hospital mortality of 17.3%. Higher documentation completeness was associated with reduced in-hospital mortality (OR 0.07, 95% CI 0.02 to 0.38, p=0.002), reduced adverse events (coef −2.08, 95% CI −2.76 to −1.390, p<0.001), and reduced duplication of labor (OR 0.19, 95% CI 0.04 to 0.88, p=0.033) when controlling for severity of illness. Conclusions Documentation completeness is associated with improved outcomes and resource utilization in patients transferred between hospitals. PMID:27591388

  8. A GIS application for assessing, mapping, and quantifying the social values of ecosystem services

    USGS Publications Warehouse

    Sherrouse, Benson C.; Clement, Jessica M.; Semmens, Darius J.

    2011-01-01

    As human pressures on ecosystems continue to increase, research involving the effective incorporation of social values information into the context of comprehensive ecosystem services assessments is becoming more important. Including quantified, spatially explicit social value metrics in such assessments will improve the analysis of relative tradeoffs among ecosystem services. This paper describes a GIS application, Social Values for Ecosystem Services (SolVES), developed to assess, map, and quantify the perceived social values of ecosystem services by deriving a non-monetary Value Index from responses to a public attitude and preference survey. SolVES calculates and maps the Value Index for social values held by various survey subgroups, as distinguished by their attitudes regarding ecosystem use. Index values can be compared within and among survey subgroups to explore the effect of social contexts on the valuation of ecosystem services. Index values can also be correlated and regressed against landscape metrics SolVES calculates from various environmental data layers. Coefficients derived through these analyses were applied to their corresponding data layers to generate a predicted social value map. This map compared favorably with other SolVES output and led to the addition of a predictive mapping function to SolVES for value transfer to areas where survey data are unavailable. A more robust application is being developed as a public domain tool for decision makers and researchers to map social values of ecosystem services and to facilitate discussions among diverse stakeholders involving relative tradeoffs among different ecosystem services in a variety of physical and social contexts.

  9. Quantifying Stock Return Distributions in Financial Markets.

    PubMed

    Botta, Federico; Moat, Helen Susannah; Stanley, H Eugene; Preis, Tobias

    2015-01-01

    Being able to quantify the probability of large price changes in stock markets is of crucial importance in understanding financial crises that affect the lives of people worldwide. Large changes in stock market prices can arise abruptly, within a matter of minutes, or develop across much longer time scales. Here, we analyze a dataset comprising the stocks forming the Dow Jones Industrial Average at a second by second resolution in the period from January 2008 to July 2010 in order to quantify the distribution of changes in market prices at a range of time scales. We find that the tails of the distributions of logarithmic price changes, or returns, exhibit power law decays for time scales ranging from 300 seconds to 3600 seconds. For larger time scales, we find that the distributions tails exhibit exponential decay. Our findings may inform the development of models of market behavior across varying time scales.

  10. NASA/DoD Aerospace Knowledge Diffusion Research Project. Paper 30: The electronic transfer of information and aerospace knowledge diffusion

    NASA Technical Reports Server (NTRS)

    Pinelli, Thomas E.; Bishop, Ann P.; Barclay, Rebecca O.; Kennedy, John M.

    1992-01-01

    Increasing reliance on and investment in information technology and electronic networking systems presupposes that computing and information technology will play a major role in the diffusion of aerospace knowledge. Little is known, however, about actual information technology needs, uses, and problems within the aerospace knowledge diffusion process. The authors state that the potential contributions of information technology to increased productivity and competitiveness will be diminished unless empirically derived knowledge regarding the information-seeking behavior of the members of the social system - those who are producing, transferring, and using scientific and technical information - is incorporated into a new technology policy framework. Research into the use of information technology and electronic networks by U.S. aerospace engineers and scientists, collected as part of a research project designed to study aerospace knowledge diffusion, is presented in support of this assertion.

  11. Integrating information from disparate sources: the Walter Reed National Surgical Quality Improvement Program Data Transfer Project.

    PubMed

    Nelson, Victoria; Nelson, Victoria Ruth; Li, Fiona; Green, Susan; Tamura, Tomoyoshi; Liu, Jun-Min; Class, Margaret

    2008-11-06

    The Walter Reed National Surgical Quality Improvement Program Data Transfer web module integrates with medical and surgical information systems, and leverages outside standards, such as the National Library of Medicine's RxNorm, to process surgical and risk assessment data. Key components of the project included a needs assessment with nurse reviewers and a data analysis for federated (standards were locally controlled) data sources. The resulting interface streamlines nurse reviewer workflow by integrating related tasks and data.

  12. Quantifying uncertainties in precipitation measurement

    NASA Astrophysics Data System (ADS)

    Chen, H. Z. D.

    2017-12-01

    The scientific community have a long history of utilizing precipitation data for climate model design. However, precipitation record and its model contains more uncertainty than its temperature counterpart. Literature research have shown precipitation measurements to be highly influenced by its surrounding environment, and weather stations are traditionally situated in open areas and subject to various limitations. As a result, this restriction limits the ability of the scientific community to fully close the loop on the water cycle. Horizontal redistribution have been shown to be a major factor influencing precipitation measurements. Efforts have been placed on reducing its effect on the monitoring apparatus. However, the amount of factors contributing to this uncertainty is numerous and difficult to fully capture. As a result, noise factor remains high in precipitation data. This study aims to quantify all uncertainties in precipitation data by factoring out horizontal redistribution by measuring them directly. Horizontal contribution of precipitation will be quantified by measuring precipitation at different heights, with one directly shadowing the other. The above collection represents traditional precipitation data, whereas the bottom measurements sums up the overall error term at given location. Measurements will be recorded and correlated with nearest available wind measurements to quantify its impact on traditional precipitation record. Collections at different locations will also be compared to see whether this phenomenon is location specific or if a general trend can be derived. We aim to demonstrate a new way to isolate the noise component in traditional precipitation data via empirical measurements. By doing so, improve the overall quality of historic precipitation record. As a result, provide a more accurate information for the design and calibration of large scale climate modeling.

  13. Information-theoretic decomposition of embodied and situated systems.

    PubMed

    Da Rold, Federico

    2018-07-01

    The embodied and situated view of cognition stresses the importance of real-time and nonlinear bodily interaction with the environment for developing concepts and structuring knowledge. In this article, populations of robots controlled by an artificial neural network learn a wall-following task through artificial evolution. At the end of the evolutionary process, time series are recorded from perceptual and motor neurons of selected robots. Information-theoretic measures are estimated on pairings of variables to unveil nonlinear interactions that structure the agent-environment system. Specifically, the mutual information is utilized to quantify the degree of dependence and the transfer entropy to detect the direction of the information flow. Furthermore, the system is analyzed with the local form of such measures, thus capturing the underlying dynamics of information. Results show that different measures are interdependent and complementary in uncovering aspects of the robots' interaction with the environment, as well as characteristics of the functional neural structure. Therefore, the set of information-theoretic measures provides a decomposition of the system, capturing the intricacy of nonlinear relationships that characterize robots' behavior and neural dynamics. Copyright © 2018 Elsevier Ltd. All rights reserved.

  14. Effect of Material Property Variations at Near Critical Thermodynamic Conditions on Pipe Flow Heat Transfer

    NASA Astrophysics Data System (ADS)

    Barney, Rebecca; Nourgaliev, Robert; Delplanque, Jean-Pierre; McCallen, Rose

    2017-11-01

    Heat transfer is quantified and contrasted for the Poiseuille flow of a fluid at both subcritical and supercritical thermodynamic conditions in a circular pipe subject to a uniform wall heat flux. The conditions considered are relevant to Supercritical Water Reactor (SCWR) applications. In the supercritical thermodynamic regime, a fluid can exhibit large density variations of density, thermal conductivity, and viscosity, which will affect flow and heat transfer characteristics significantly. An advanced equation of state for supercritical water was implemented in a 2D and 3D Arbitrary Lagrangian-Eurlerian multi-physics simulation tool called ALE3D developed at Lawrence Livermore National Laboratory. A newly developed, robust, high-order in space and time, fully implicit reconstructed discontinuous Galerkin (rDG) method is used to enable the numerical simulation of convective heat transfer with supercritical water. Results demonstrate the capability of this approach to accurately capture the non-linear behavior and enhanced heat transfer with supercritical water. This work was performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344. Information management release number LLNL-ABS-736004. Work is supported by the Integrated University Program Graduate Fellowship. Opinions, findings, conclusions or recommendations expressed are of the authors and do not necessarily reflect the views of DOE office of NE.

  15. A framework for quantifying and optimizing the value of seismic monitoring of infrastructure

    NASA Astrophysics Data System (ADS)

    Omenzetter, Piotr

    2017-04-01

    This paper outlines a framework for quantifying and optimizing the value of information from structural health monitoring (SHM) technology deployed on large infrastructure, which may sustain damage in a series of earthquakes (the main and the aftershocks). The evolution of the damage state of the infrastructure without or with SHM is presented as a time-dependent, stochastic, discrete-state, observable and controllable nonlinear dynamical system. The pre-posterior Bayesian analysis and the decision tree are used for quantifying and optimizing the value of SHM information. An optimality problem is then formulated how to decide on the adoption of SHM and how to manage optimally the usage and operations of the possibly damaged infrastructure and its repair schedule using the information from SHM. The objective function to minimize is the expected total cost or risk.

  16. Chemical exchange rotation transfer (CERT) on human brain at 3 Tesla.

    PubMed

    Lin, Eugene C; Li, Hua; Zu, Zhongliang; Louie, Elizabeth A; Lankford, Christopher L; Dortch, Richard D; Does, Mark D; Gore, John C; Gochberg, Daniel F

    2018-05-25

    To test the ability of a novel pulse sequence applied in vivo at 3 Tesla to separate the contributions to the water signal from amide proton transfer (APT) and relayed nuclear Overhauser enhancement (rNOE) from background direct water saturation and semisolid magnetization transfer (MT). The lack of such signal source isolation has confounded conventional chemical exchange saturation transfer (CEST) imaging. We quantified APT and rNOE signals using a chemical exchange rotation transfer (CERT) metric, MTR double . A range of duty cycles and average irradiation powers were applied, and results were compared with conventional CEST analyses using asymmetry (MTR asym ) and extrapolated magnetization transfer (EMR). Our results indicate that MTR double is more specific than MTR asym and, because it requires as few as 3 data points, is more rapid than methods requiring a complete Z-spectrum, such as EMR. In white matter, APT (1.5 ± 0.5%) and rNOE (2.1 ± 0.7%) were quantified by using MTR double with a 30% duty cycle and a 0.5-µT average power. In addition, our results suggest that MTR double is insensitive to B 0 inhomogeneity, further magnifying its speed advantage over CEST metrics that require a separate B 0 measurement. However, MTR double still has nontrivial sensitivity to B 1 inhomogeneities. We demonstrated that MTR double is an alternative metric to evaluate APT and rNOE, which is fast, robust to B 0 inhomogeneity, and easy to process. © 2018 International Society for Magnetic Resonance in Medicine.

  17. Patient Transfers and Risk of Back Injury: Protocol for a Prospective Cohort Study With Technical Measurements of Exposure.

    PubMed

    Vinstrup, Jonas; Madeleine, Pascal; Jakobsen, Markus Due; Jay, Kenneth; Andersen, Lars Louis

    2017-11-08

    More than one third of nurses experience musculoskeletal pain several times during a normal work week. Consistent use of assistive devices during patient transfers is associated with a lower risk of occupational back injuries and low back pain (LBP). While uncertainties exist regarding which type of assistive devices most efficiently prevent LBP, exposure assessments using technological advancements allow for quantification of muscle load and body positions during common work tasks. The main objectives of this study are (1) to quantify low back and neck/shoulder muscle load in Danish nurses during patient transfers performed with different types of assistive devices, and (2) to combine the exposure profile for each type of assistive device with fortnightly questionnaires to identify the importance of muscle load (intensity and frequency of transfers) and body position (degree of back inclination and frequency) on LBP intensity and risk of back injury during a patient transfer. A combination of technical measurements (n=50) and a prospective study design (n=2000) will be applied on a cohort of female nurses in Danish hospitals. The technical measurements will be comprised of surface electromyography and accelerometers, with the aim of quantifying muscle load and body positions during various patient transfers, including different types of assistive devices throughout a workday. The study will thereby gather measurements during real-life working conditions. The prospective cohort study will consist of questionnaires at baseline and 1-year follow-up, as well as follow-up via email every other week for one year on questions regarding the frequency of patient transfers, use of assistive devices, intensity of LBP, and back injuries related to patient transfers. The objective measurements on muscle load and body positions during patient handlings will be applied to the fortnightly replies regarding frequency of patient transfer and use of different assistive devices, in

  18. Amplification of Information by Photons and the Quantum Chernoff Bound

    NASA Astrophysics Data System (ADS)

    Zwolak, Michael; Riedel, C. Jess; Zurek, Wojciech H.

    2014-03-01

    Amplification was regarded, since the early days of quantum theory, as a mysterious ingredient that endows quantum microstates with macroscopic consequences, key to the ``collapse of the wavepacket,'' and a way to avoid embarrassing problems exemplified by Schrödinger's cat. This bridge between the quantum microworld and the classical world of our experience was postulated ad hoc in the Copenhagen Interpretation. Quantum Darwinism views amplification as replication, in many copies, of information about quantum states. We show that such amplification is a natural consequence of a broad class of models of decoherence, including the photon environment we use to obtain most of our information. The resultant amplification is huge, proportional to # ξQCB . Here, #  is the environment size and ξQCB is the ``typical'' Quantum Chernoff Information, which quantifies the efficiency of the amplification. The information communicated though the environment is imprinted in the states of individual environment subsystems, e.g., in single photons, which document the transfer of information into the environment and result in the emergence of the classical world. See, http://mike.zwolak.org

  19. Interrogating Host-virus Interactions and Elemental Transfer Using NanoSIMS

    NASA Astrophysics Data System (ADS)

    Pasulka, A.; Thamatrakoln, K.; Poulos, B.; Bidle, K. D.; Sullivan, M. B.; Orphan, V. J.

    2016-02-01

    Marine viruses (bacteriophage and eukaryotic viruses) impact microbial food webs by influencing microbial community structure, carbon and nutrient flow, and serving as agents of gene transfer. While the collective impact of viral activity has become more apparent over the last decade, there is a growing need for single-cell and single-virus level measurements of the associated carbon and nitrogen transfer, which ultimately shape the biogeochemical impact of viruses in the upper ocean. Stable isotopes have been used extensively for understanding trophic relationships and elemental cycling in marine food webs. While single-cell isotope approaches such as nanoscale secondary ion mass spectrometry (nanoSIMS) have been more readily used to study trophic interactions between microorganisms, isotopic enrichment in viruses has not been described. Here we used nanoSIMS to quantify the transfer of stable isotopes (13C and 15N) from host to individual viral particles in two distinct unicellular algal-virus model systems. These model systems represent a eukaryotic phytoplankton (Emiliania huxleyi strain CCMP374) and its 200nm coccolithovirus (EhV207), as well as a cyanobacterial phytoplankton (Synechococcus WH8101) and its 80nm virus (Syn1). Host cells were grown on labeled media for multiple generations, subjected to viral infection, and then viruses were harvested after lysis. In both cases, nanoSIMS measurements were able to detect 13C and 15N in the resulting viral particles significantly above the background noise. The isotopic enrichment in the viral particles mirrored that of the host. Through use of these laboratory model systems, we quantified the sensitivity (ion counts), spatial resolution, and reproducibility, including sources of methodological and biological variability, in stable isotope incorporation into viral particles. Our findings suggest that nanoSIMS can be successfully employed to directly probe virus-host interactions at the resolution of individual

  20. Neural basis for generalized quantifier comprehension.

    PubMed

    McMillan, Corey T; Clark, Robin; Moore, Peachie; Devita, Christian; Grossman, Murray

    2005-01-01

    Generalized quantifiers like "all cars" are semantically well understood, yet we know little about their neural representation. Our model of quantifier processing includes a numerosity device, operations that combine number elements and working memory. Semantic theory posits two types of quantifiers: first-order quantifiers identify a number state (e.g. "at least 3") and higher-order quantifiers additionally require maintaining a number state actively in working memory for comparison with another state (e.g. "less than half"). We used BOLD fMRI to test the hypothesis that all quantifiers recruit inferior parietal cortex associated with numerosity, while only higher-order quantifiers recruit prefrontal cortex associated with executive resources like working memory. Our findings showed that first-order and higher-order quantifiers both recruit right inferior parietal cortex, suggesting that a numerosity component contributes to quantifier comprehension. Moreover, only probes of higher-order quantifiers recruited right dorsolateral prefrontal cortex, suggesting involvement of executive resources like working memory. We also observed activation of thalamus and anterior cingulate that may be associated with selective attention. Our findings are consistent with a large-scale neural network centered in frontal and parietal cortex that supports comprehension of generalized quantifiers.

  1. Coherent Structures and Spectral Energy Transfer in Turbulent Plasma: A Space-Filter Approach.

    PubMed

    Camporeale, E; Sorriso-Valvo, L; Califano, F; Retinò, A

    2018-03-23

    Plasma turbulence at scales of the order of the ion inertial length is mediated by several mechanisms, including linear wave damping, magnetic reconnection, the formation and dissipation of thin current sheets, and stochastic heating. It is now understood that the presence of localized coherent structures enhances the dissipation channels and the kinetic features of the plasma. However, no formal way of quantifying the relationship between scale-to-scale energy transfer and the presence of spatial structures has been presented so far. In the Letter we quantify such a relationship analyzing the results of a two-dimensional high-resolution Hall magnetohydrodynamic simulation. In particular, we employ the technique of space filtering to derive a spectral energy flux term which defines, in any point of the computational domain, the signed flux of spectral energy across a given wave number. The characterization of coherent structures is performed by means of a traditional two-dimensional wavelet transformation. By studying the correlation between the spectral energy flux and the wavelet amplitude, we demonstrate the strong relationship between scale-to-scale transfer and coherent structures. Furthermore, by conditioning one quantity with respect to the other, we are able for the first time to quantify the inhomogeneity of the turbulence cascade induced by topological structures in the magnetic field. Taking into account the low space-filling factor of coherent structures (i.e., they cover a small portion of space), it emerges that 80% of the spectral energy transfer (both in the direct and inverse cascade directions) is localized in about 50% of space, and 50% of the energy transfer is localized in only 25% of space.

  2. Coherent Structures and Spectral Energy Transfer in Turbulent Plasma: A Space-Filter Approach

    NASA Astrophysics Data System (ADS)

    Camporeale, E.; Sorriso-Valvo, L.; Califano, F.; Retinò, A.

    2018-03-01

    Plasma turbulence at scales of the order of the ion inertial length is mediated by several mechanisms, including linear wave damping, magnetic reconnection, the formation and dissipation of thin current sheets, and stochastic heating. It is now understood that the presence of localized coherent structures enhances the dissipation channels and the kinetic features of the plasma. However, no formal way of quantifying the relationship between scale-to-scale energy transfer and the presence of spatial structures has been presented so far. In the Letter we quantify such a relationship analyzing the results of a two-dimensional high-resolution Hall magnetohydrodynamic simulation. In particular, we employ the technique of space filtering to derive a spectral energy flux term which defines, in any point of the computational domain, the signed flux of spectral energy across a given wave number. The characterization of coherent structures is performed by means of a traditional two-dimensional wavelet transformation. By studying the correlation between the spectral energy flux and the wavelet amplitude, we demonstrate the strong relationship between scale-to-scale transfer and coherent structures. Furthermore, by conditioning one quantity with respect to the other, we are able for the first time to quantify the inhomogeneity of the turbulence cascade induced by topological structures in the magnetic field. Taking into account the low space-filling factor of coherent structures (i.e., they cover a small portion of space), it emerges that 80% of the spectral energy transfer (both in the direct and inverse cascade directions) is localized in about 50% of space, and 50% of the energy transfer is localized in only 25% of space.

  3. SHOOT performance testing. [Superfluid Helium On-Orbit Transfer Flight Demonstration

    NASA Technical Reports Server (NTRS)

    Dipirro, M. J.; Shirron, P. J.; Volz, S. M.; Schein, M. E.

    1991-01-01

    The Superfluid Helium On-Orbit Transfer (SHOOT) Flight Demonstration is a shuttle attached payload designed to demonstrate the technology necessary to resupply liquid helium dewars in space. Many SHOOT components will also have use in other aerospace cryogenic systems. The first of two SHOOT dewar systems has been fabricated. The ground performance testing of this dewar is described. The performance tests include measurements of heat leak, impedances of the two vent lines, heat pulse mass gauging accuracy, and superfluid transfer parameters such as flow rate and efficiency. A laboratory dewar was substituted for the second flight dewar for the transfer tests. These tests enable a precise analytical model of the transfer process to be verified. SHOOT performance is thus quantified, except for components such as the liquid acquisition devices and a phase separator which cannot be verified in one gravity.

  4. Transfer and utilization of government technology assets to the private sector in the fields of health care and information technologies

    NASA Astrophysics Data System (ADS)

    Kun, Luis G.

    1995-10-01

    During the first Health Care Technology Policy conference last year, during health care reform, four major issues were brought up in regards to the efforts underway to develop a computer based patient record (CBPR), the National Information Infrastructure (NII) as part of the high performance computers and communications (HPCC), and the so-called 'patient card.' More specifically it was explained how a national information system will greatly affect the way health care delivery is provided to the United States public and reduce its costs. These four issues were: (1) Constructing a national information infrastructure (NII); (2) Building a computer based patient record system; (3) Bringing the collective resources of our national laboratories to bear in developing and implementing the NII and CBPR, as well as a security system with which to safeguard the privacy rights of patients and the physician-patient privilege; (4) Utilizing government (e.g., DOD, DOE) capabilities (technology and human resources) to maximize resource utilization, create new jobs, and accelerate technology transfer to address health care issues. This year a section of this conference entitled: 'Health Care Technology Assets of the Federal Government' addresses benefits of the technology transfer which should occur for maximizing already developed resources. This section entitled: 'Transfer and Utilization of Government Technology Assets to the Private Sector,' will look at both health care and non-health care related technologies since many areas such as information technologies (i.e. imaging, communications, archival/retrieval, systems integration, information display, multimedia, heterogeneous data bases, etc.) already exist and are part of our national labs and/or other federal agencies, i.e., ARPA. These technologies although they are not labeled under health care programs they could provide enormous value to address technical needs. An additional issue deals with both the technical

  5. Rehabilitation Risk Management: Enabling Data Analytics with Quantified Self and Smart Home Data.

    PubMed

    Hamper, Andreas; Eigner, Isabella; Wickramasinghe, Nilmini; Bodendorf, Freimut

    2017-01-01

    A variety of acute and chronic diseases require rehabilitation at home after treatment. Outpatient rehabilitation is crucial for the quality of the medical outcome but is mainly performed without medical supervision. Non-Compliance can lead to severe health risks and readmission to the hospital. While the patient is closely monitored in the hospital, methods and technologies to identify risks at home have to be developed. We analyze state-of-the-art monitoring systems and technologies and show possibilities to transfer these technologies into rehabilitation monitoring. For this purpose, we analyze sensor technology from the field of Quantified Self and Smart Homes. The available sensor data from this consumer grade technology is summarized to give an overview of the possibilities for medical data analytics. Subsequently, we show a conceptual roadmap to transfer data analytics methods to sensor based rehabilitation risk management.

  6. The College Handbook for Transfer Students, 1991.

    ERIC Educational Resources Information Center

    College Board, New York, NY.

    The directory provides current information designed to assist college students desiring to transfer in the selection of their new college or university. The handbook provides the specific information needed about transfer policies at 2,800 two-year and four-year U.S. colleges. College descriptions are alphabetical by state. In addition to general…

  7. 22 CFR 62.76 - Transfer procedures.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... at a time specified by the transfer sponsor, and shall provide updated U.S. address information. (v... sponsor in a manner and at a time specified by the transfer sponsor and shall provide updated U.S. address... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Transfer procedures. 62.76 Section 62.76...

  8. 22 CFR 62.76 - Transfer procedures.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... at a time specified by the transfer sponsor, and shall provide updated U.S. address information. (v... sponsor in a manner and at a time specified by the transfer sponsor and shall provide updated U.S. address... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Transfer procedures. 62.76 Section 62.76...

  9. 22 CFR 62.76 - Transfer procedures.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... at a time specified by the transfer sponsor, and shall provide updated U.S. address information. (v... sponsor in a manner and at a time specified by the transfer sponsor and shall provide updated U.S. address... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Transfer procedures. 62.76 Section 62.76...

  10. 22 CFR 62.76 - Transfer procedures.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... at a time specified by the transfer sponsor, and shall provide updated U.S. address information. (v... sponsor in a manner and at a time specified by the transfer sponsor and shall provide updated U.S. address... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Transfer procedures. 62.76 Section 62.76...

  11. 22 CFR 62.76 - Transfer procedures.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... at a time specified by the transfer sponsor, and shall provide updated U.S. address information. (v... sponsor in a manner and at a time specified by the transfer sponsor and shall provide updated U.S. address... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Transfer procedures. 62.76 Section 62.76...

  12. Virtual versus real water transfers within China

    PubMed Central

    Ma, Jing; Hoekstra, Arjen Y; Wang, Hao; Chapagain, Ashok K; Wang, Dangxian

    2005-01-01

    North China faces severe water scarcity—more than 40% of the annual renewable water resources are abstracted for human use. Nevertheless, nearly 10% of the water used in agriculture is employed in producing food exported to south China. To compensate for this ‘virtual water flow’ and to reduce water scarcity in the north, the huge south–north Water Transfer Project is currently being implemented. This paradox—the transfer of huge volumes of water from the water-rich south to the water-poor north versus transfer of substantial volumes of food from the food-sufficient north to the food-deficit south—is receiving increased attention, but the research in this field has not yet reached further than rough estimation and qualitative description. The aim of this paper is to review and quantify the volumes of virtual water flows between the regions in China and to put them in the context of water availability per region. The analysis shows that north China annually exports about 52 billion m3 of water in virtual form to south China, which is more than the maximum proposed water transfer volume along the three routes of the Water Transfer Project from south to north. PMID:16767828

  13. Beyond the Information Given: Infants' Transfer of Actions Learned through Imitation

    ERIC Educational Resources Information Center

    Yang, Dahe; Sidman, Jason; Bushnell, Emily W.

    2010-01-01

    Five experiments were conducted to investigate infants' ability to transfer actions learned via imitation to new objects and to examine what components of the original context are critical to such transfer. Infants of 15 months observed an experimenter perform an action with one or two toys and then were offered a novel toy that was not…

  14. Quantifying Stock Return Distributions in Financial Markets

    PubMed Central

    Botta, Federico; Moat, Helen Susannah; Stanley, H. Eugene; Preis, Tobias

    2015-01-01

    Being able to quantify the probability of large price changes in stock markets is of crucial importance in understanding financial crises that affect the lives of people worldwide. Large changes in stock market prices can arise abruptly, within a matter of minutes, or develop across much longer time scales. Here, we analyze a dataset comprising the stocks forming the Dow Jones Industrial Average at a second by second resolution in the period from January 2008 to July 2010 in order to quantify the distribution of changes in market prices at a range of time scales. We find that the tails of the distributions of logarithmic price changes, or returns, exhibit power law decays for time scales ranging from 300 seconds to 3600 seconds. For larger time scales, we find that the distributions tails exhibit exponential decay. Our findings may inform the development of models of market behavior across varying time scales. PMID:26327593

  15. Tech Transfer News. Volume 9, No. 1

    NASA Technical Reports Server (NTRS)

    Victor, Megan E. (Compiler)

    2017-01-01

    Kennedy Tech Transfer News is the magazine of the Technology Transfer Office at NASA's Kennedy Space Center, Florida. This magazine seeks to inform and educate civil servant and contractor personnel at Kennedy Space Center about actively participating in achieving NASA's technology transfer and partnership goals.

  16. Enabling the BC Transfer System: A Discussion Paper

    ERIC Educational Resources Information Center

    British Columbia Council on Admissions and Transfer, 2011

    2011-01-01

    This discussion paper outlines processes, as well as opportunities and constraints, for "enabling" BC Transfer System institutions to enhance transfer credit information in the BC Transfer Guide, making it more reflective of institutional practices and student mobility. BCCAT's focus is increasing the availability of transfer credit…

  17. Making the business case for hospital information systems--a Kaiser Permanente investment decision.

    PubMed

    Garrido, Terhilda; Raymond, Brian; Jamieson, Laura; Liang, Louise; Wiesenthal, Andrew

    2004-01-01

    Further evidence in favor of the clinical IT business case is set forth in Kaiser Permanente's cost/benefit analysis for an electronic hospital information system. This article reviews the business case for an inpatient electronic medical record system, including 36 categories of quantifiable benefits that contribute to a positive cumulative net cash flow within an 8.5 year period. However, the business case hinges on several contingent success factors: leadership commitment, timely implementation, partnership with labor, coding compliance, and workflow redesign. The issues and constraints that impact the potential transferability of this business case across delivery systems raise questions that merit further attention.

  18. Vortex dynamics and heat transfer behind self-oscillating inverted flags of various lengths in channel flow

    NASA Astrophysics Data System (ADS)

    Yu, Yuelong; Liu, Yingzheng; Chen, Yujia

    2018-04-01

    The influence of an inverted flag's length-to-channel-width ratio (C* = L/W) on its oscillating behavior in a channel flow and the resultant vortex dynamics and heat transfer are determined experimentally. Three systems with C* values of 0.125, 0.250, and 0.375 were chosen for comparison. The interaction of highly unsteady flow with the inverted flag is measured with time-resolved particle image velocimetry. Variations in the underlying flow physics are discussed in terms of the statistical flow quantities, flag displacement, phase-averaged flow field, and vortex dynamics. The results show that the increase in C* shifts the occurrence of the flapping regime at high dimensionless bending stiffness. With the flag in the flapping region, three distinct vortex dynamics—the von Kármán vortex street, the G mode, and the singular mode—are identified at C* values of 0.375, 0.250, and 0.125, respectively. Finally, the heat transfer enhancement from the self-oscillating inverted flag is measured to serve as complementary information to quantify the cause-and-effect relationship between vortex dynamics and wall heat transfer. The increase in C* strongly promotes wall heat removal because disruption of the boundary layer by the energetic vortices is substantially intensified. Among all systems, wall heat transfer removal is most efficient at the intermediate C* value of 0.250.

  19. A preliminary study of the impact of a handover cognitive aid on clinical reasoning and information transfer.

    PubMed

    Weiss, Matthew J; Bhanji, Farhan; Fontela, Patricia S; Razack, Saleem I

    2013-08-01

    To assess the impact of a written cognitive aid on expressed clinical reasoning and quantity and the accuracy of information transfer during resident doctor handover. This study was a randomised controlled trial in an academic paediatric intensive care unit (PICU) of 20 handover events (10 events per group) from residents in their first PICU rotation using a written handover cognitive aid (intervention) or standard practice (control). Before rounds, an investigator generated a reference standard of the handover event by completing a handover aid. Resident handovers were then audio-recorded and transcribed by a blinded research assistant. The content of this transcript was inserted into a blank handover aid. A blinded content expert scored the quantity and accuracy of the information in this aid according to predetermined criteria and these information scores (ISs) were compared with the reference standard. The same expert also blindly scored the transcripts in five domains of clinical reasoning and effectiveness: (i) effective summary of events; (ii) expressed understanding of the care plan; (iii) presentation clarity; (iv) organisation; (v) overall handover effectiveness. Differences between intervention and control groups were assessed using the Mann-Whitney test and multivariate linear regression. The intervention group had total ISs that more closely approximated the reference standard (81% versus 61%; p < 0.01). The intervention group had significantly higher clinical reasoning scores when compared by total score (21.1 versus 15.9 points; p = 0.01) and in each of the five domains. No difference was observed in the duration of handover between groups (7.4 versus 7.7 minutes; p = 0.97). Using a novel scoring system, our simple handover cognitive aid was shown to improve information transfer and resident expression of clinical reasoning without prolonging the handover duration. © 2013 John Wiley & Sons Ltd.

  20. Quantifying temporal change in biodiversity: challenges and opportunities

    PubMed Central

    Dornelas, Maria; Magurran, Anne E.; Buckland, Stephen T.; Chao, Anne; Chazdon, Robin L.; Colwell, Robert K.; Curtis, Tom; Gaston, Kevin J.; Gotelli, Nicholas J.; Kosnik, Matthew A.; McGill, Brian; McCune, Jenny L.; Morlon, Hélène; Mumby, Peter J.; Øvreås, Lise; Studeny, Angelika; Vellend, Mark

    2013-01-01

    Growing concern about biodiversity loss underscores the need to quantify and understand temporal change. Here, we review the opportunities presented by biodiversity time series, and address three related issues: (i) recognizing the characteristics of temporal data; (ii) selecting appropriate statistical procedures for analysing temporal data; and (iii) inferring and forecasting biodiversity change. With regard to the first issue, we draw attention to defining characteristics of biodiversity time series—lack of physical boundaries, uni-dimensionality, autocorrelation and directionality—that inform the choice of analytic methods. Second, we explore methods of quantifying change in biodiversity at different timescales, noting that autocorrelation can be viewed as a feature that sheds light on the underlying structure of temporal change. Finally, we address the transition from inferring to forecasting biodiversity change, highlighting potential pitfalls associated with phase-shifts and novel conditions. PMID:23097514

  1. Virtual groundwater transfers from overexploited aquifers in the United States.

    PubMed

    Marston, Landon; Konar, Megan; Cai, Ximing; Troy, Tara J

    2015-07-14

    The High Plains, Mississippi Embayment, and Central Valley aquifer systems within the United States are currently being overexploited for irrigation water supplies. The unsustainable use of groundwater resources in all three aquifer systems intensified from 2000 to 2008, making it imperative that we understand the consumptive processes and forces of demand that are driving their depletion. To this end, we quantify and track agricultural virtual groundwater transfers from these overexploited aquifer systems to their final destination. Specifically, we determine which US metropolitan areas, US states, and international export destinations are currently the largest consumers of these critical aquifers. We draw upon US government data on agricultural production, irrigation, and domestic food flows, as well as modeled estimates of agricultural virtual water contents to quantify domestic transfers. Additionally, we use US port-level trade data to trace international exports from these aquifers. In 2007, virtual groundwater transfers from the High Plains, Mississippi Embayment, and Central Valley aquifer systems totaled 17.93 km(3), 9.18 km(3), and 6.81 km(3), respectively, which is comparable to the capacity of Lake Mead (35.7 km(3)), the largest surface reservoir in the United States. The vast majority (91%) of virtual groundwater transfers remains within the United States. Importantly, the cereals produced by these overexploited aquifers are critical to US food security (contributing 18.5% to domestic cereal supply). Notably, Japan relies upon cereals produced by these overexploited aquifers for 9.2% of its domestic cereal supply. These results highlight the need to understand the teleconnections between distant food demands and local agricultural water use.

  2. Quantification of unsteady heat transfer and phase changing process inside small icing water droplets.

    PubMed

    Jin, Zheyan; Hu, Hui

    2009-05-01

    We report progress made in our recent effort to develop and implement a novel, lifetime-based molecular tagging thermometry (MTT) technique to quantify unsteady heat transfer and phase changing process inside small icing water droplets pertinent to wind turbine icing phenomena. The lifetime-based MTT technique was used to achieve temporally and spatially resolved temperature distribution measurements within small, convectively cooled water droplets to quantify unsteady heat transfer within the small water droplets in the course of convective cooling process. The transient behavior of phase changing process within small icing water droplets was also revealed clearly by using the MTT technique. Such measurements are highly desirable to elucidate underlying physics to improve our understanding about important microphysical phenomena pertinent to ice formation and accreting process as water droplets impinging onto wind turbine blades.

  3. The Transfer of Training: What Really Matters

    ERIC Educational Resources Information Center

    Grossman, Rebecca; Salas, Eduardo

    2011-01-01

    Although organizations invest billions of dollars in training every year, many trained competencies reportedly fail to transfer to the workplace. Researchers have long examined the "transfer problem", uncovering a wealth of information regarding the transfer of training. Inconsistencies remain, however, and organizations may find it difficult to…

  4. Quantifier Comprehension in Corticobasal Degeneration

    ERIC Educational Resources Information Center

    McMillan, Corey T.; Clark, Robin; Moore, Peachie; Grossman, Murray

    2006-01-01

    In this study, we investigated patients with focal neurodegenerative diseases to examine a formal linguistic distinction between classes of generalized quantifiers, like "some X" and "less than half of X." Our model of quantifier comprehension proposes that number knowledge is required to understand both first-order and higher-order quantifiers.…

  5. Data and Time Transfer Using SONET Radio

    NASA Technical Reports Server (NTRS)

    Graceffo, Gary M.

    1996-01-01

    The need for precise knowledge of time and frequency has become ubiquitous throughout our society. The areas of astronomy, navigation, and high speed wide-area networks are among a few of the many consumers of this type of information. The Global Positioning System (GPS) has the potential to be the most comprehensive source of precise timing information developed to date; however, the introduction of selective availability has made it difficult for many users to recover this information from the GPS system with the precision required for today's systems. The system described in this paper is a 'Synchronous Optical NetWORK (SONET) Radio Data and Time Transfer System'. The objective of this system is to provide precise time and frequency information to a variety of end-users using a two-way data and time-transfer system. Although time and frequency transfers have been done for many years, this system is unique in that time and frequency information are embedded into existing communications traffic. This eliminates the need to make the transfer of time and frequency informatio a dedicated function of the communications system. For this system SONET has been selected as the transport format from which precise time is derived. SONET has been selected because of its high data rates and its increasing acceptance throughout the industry. This paper details a proof-of-concept initiative to perform embedded time and frequency transfers using SONET Radio.

  6. Use of information entropy measures of sitting postural sway to quantify developmental delay in infants

    PubMed Central

    Deffeyes, Joan E; Harbourne, Regina T; DeJong, Stacey L; Kyvelidou, Anastasia; Stuberg, Wayne A; Stergiou, Nicholas

    2009-01-01

    Background By quantifying the information entropy of postural sway data, the complexity of the postural movement of different populations can be assessed, giving insight into pathologic motor control functioning. Methods In this study, developmental delay of motor control function in infants was assessed by analysis of sitting postural sway data acquired from force plate center of pressure measurements. Two types of entropy measures were used: symbolic entropy, including a new asymmetric symbolic entropy measure, and approximate entropy, a more widely used entropy measure. For each method of analysis, parameters were adjusted to optimize the separation of the results from the infants with delayed development from infants with typical development. Results The method that gave the widest separation between the populations was the asymmetric symbolic entropy method, which we developed by modification of the symbolic entropy algorithm. The approximate entropy algorithm also performed well, using parameters optimized for the infant sitting data. The infants with delayed development were found to have less complex patterns of postural sway in the medial-lateral direction, and were found to have different left-right symmetry in their postural sway, as compared to typically developing infants. Conclusion The results of this study indicate that optimization of the entropy algorithm for infant sitting postural sway data can greatly improve the ability to separate the infants with developmental delay from typically developing infants. PMID:19671183

  7. Detecting the chaotic nature in a transitional boundary layer using symbolic information-theory quantifiers.

    PubMed

    Zhang, Wen; Liu, Peiqing; Guo, Hao; Wang, Jinjun

    2017-11-01

    The permutation entropy and the statistical complexity are employed to study the boundary-layer transition induced by the surface roughness. The velocity signals measured in the transition process are analyzed with these symbolic quantifiers, as well as the complexity-entropy causality plane, and the chaotic nature of the instability fluctuations is identified. The frequency of the dominant fluctuations has been found according to the time scales corresponding to the extreme values of the symbolic quantifiers. The laminar-turbulent transition process is accompanied by the evolution in the degree of organization of the complex eddy motions, which is also characterized with the growing smaller and flatter circles in the complexity-entropy causality plane. With the help of the permutation entropy and the statistical complexity, the differences between the chaotic fluctuations detected in the experiments and the classical Tollmien-Schlichting wave are shown and discussed. It is also found that the chaotic features of the instability fluctuations can be approximated with a number of regular sine waves superimposed on the fluctuations of the undisturbed laminar boundary layer. This result is related to the physical mechanism in the generation of the instability fluctuations, which is the noise-induced chaos.

  8. Detecting the chaotic nature in a transitional boundary layer using symbolic information-theory quantifiers

    NASA Astrophysics Data System (ADS)

    Zhang, Wen; Liu, Peiqing; Guo, Hao; Wang, Jinjun

    2017-11-01

    The permutation entropy and the statistical complexity are employed to study the boundary-layer transition induced by the surface roughness. The velocity signals measured in the transition process are analyzed with these symbolic quantifiers, as well as the complexity-entropy causality plane, and the chaotic nature of the instability fluctuations is identified. The frequency of the dominant fluctuations has been found according to the time scales corresponding to the extreme values of the symbolic quantifiers. The laminar-turbulent transition process is accompanied by the evolution in the degree of organization of the complex eddy motions, which is also characterized with the growing smaller and flatter circles in the complexity-entropy causality plane. With the help of the permutation entropy and the statistical complexity, the differences between the chaotic fluctuations detected in the experiments and the classical Tollmien-Schlichting wave are shown and discussed. It is also found that the chaotic features of the instability fluctuations can be approximated with a number of regular sine waves superimposed on the fluctuations of the undisturbed laminar boundary layer. This result is related to the physical mechanism in the generation of the instability fluctuations, which is the noise-induced chaos.

  9. Technology transfer methodology

    NASA Technical Reports Server (NTRS)

    Labotz, Rich

    1991-01-01

    Information on technology transfer methodology is given in viewgraph form. Topics covered include problems in economics, technology drivers, inhibitors to using improved technology in development, technology application opportunities, and co-sponsorship of technology.

  10. Workshop: Benefits Transfer Workshop Proceedings (2005)

    EPA Pesticide Factsheets

    The objective of the workshop was to provide a forum for informed discussion regarding the practice of benefits transfer, the use of valuation databases for such, and the general relevance of valuation and benefits transfer to environmental decision making

  11. Diesel Emissions Quantifier (DEQ)

    EPA Pesticide Factsheets

    .The Diesel Emissions Quantifier (Quantifier) is an interactive tool to estimate emission reductions and cost effectiveness. Publications EPA-420-F-13-008a (420f13008a), EPA-420-B-10-035 (420b10023), EPA-420-B-10-034 (420b10034)

  12. Measurement and modeling of transfer functions for lightning coupling into the Sago mine.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Morris, Marvin E.; Higgins, Matthew B.

    2007-04-01

    This report documents measurements and analytical modeling of electromagnetic transfer functions to quantify the ability of cloud-to-ground lightning strokes (including horizontal arc-channel components) to couple electromagnetic energy into the Sago mine located near Buckhannon, WV. Two coupling mechanisms were measured: direct and indirect drive. These transfer functions are then used to predict electric fields within the mine and induced voltages on conductors that were left abandoned in the sealed area of the Sago mine.

  13. The Impact of Different Sources of Fluctuations on Mutual Information in Biochemical Networks

    PubMed Central

    Chevalier, Michael; Venturelli, Ophelia; El-Samad, Hana

    2015-01-01

    Stochastic fluctuations in signaling and gene expression limit the ability of cells to sense the state of their environment, transfer this information along cellular pathways, and respond to it with high precision. Mutual information is now often used to quantify the fidelity with which information is transmitted along a cellular pathway. Mutual information calculations from experimental data have mostly generated low values, suggesting that cells might have relatively low signal transmission fidelity. In this work, we demonstrate that mutual information calculations might be artificially lowered by cell-to-cell variability in both initial conditions and slowly fluctuating global factors across the population. We carry out our analysis computationally using a simple signaling pathway and demonstrate that in the presence of slow global fluctuations, every cell might have its own high information transmission capacity but that population averaging underestimates this value. We also construct a simple synthetic transcriptional network and demonstrate using experimental measurements coupled to computational modeling that its operation is dominated by slow global variability, and hence that its mutual information is underestimated by a population averaged calculation. PMID:26484538

  14. Quantifying the Climate-Scale Accuracy of Satellite Cloud Retrievals

    NASA Astrophysics Data System (ADS)

    Roberts, Y.; Wielicki, B. A.; Sun-Mack, S.; Minnis, P.; Liang, L.; Di Girolamo, L.

    2014-12-01

    Instrument calibration and cloud retrieval algorithms have been developed to minimize retrieval errors on small scales. However, measurement uncertainties and assumptions within retrieval algorithms at the pixel level may alias into decadal-scale trends of cloud properties. We first, therefore, quantify how instrument calibration changes could alias into cloud property trends. For a perfect observing system the climate trend accuracy is limited only by the natural variability of the climate variable. Alternatively, for an actual observing system, the climate trend accuracy is additionally limited by the measurement uncertainty. Drifts in calibration over time may therefore be disguised as a true climate trend. We impose absolute calibration changes to MODIS spectral reflectance used as input to the CERES Cloud Property Retrieval System (CPRS) and run the modified MODIS reflectance through the CPRS to determine the sensitivity of cloud properties to calibration changes. We then use these changes to determine the impact of instrument calibration changes on trend uncertainty in reflected solar cloud properties. Secondly, we quantify how much cloud retrieval algorithm assumptions alias into cloud optical retrieval trends by starting with the largest of these biases: the plane-parallel assumption in cloud optical thickness (τC) retrievals. First, we collect liquid water cloud fields obtained from Multi-angle Imaging Spectroradiometer (MISR) measurements to construct realistic probability distribution functions (PDFs) of 3D cloud anisotropy (a measure of the degree to which clouds depart from plane-parallel) for different ISCCP cloud types. Next, we will conduct a theoretical study with dynamically simulated cloud fields and a 3D radiative transfer model to determine the relationship between 3D cloud anisotropy and 3D τC bias for each cloud type. Combining these results provides distributions of 3D τC bias by cloud type. Finally, we will estimate the change in

  15. New measurements quantify atmospheric greenhouse effect

    NASA Astrophysics Data System (ADS)

    Bhattacharya, Atreyee

    2012-10-01

    In spite of a large body of existing measurements of incoming short-wave solar radiation and outgoing long-wave terrestrial radiation at the surface of the Earth and, more recently, in the upper atmosphere, there are few observations documenting how radiation profiles change through the atmosphere—information that is necessary to fully quantify the greenhouse effect of Earth's atmosphere. Through the use of existing technology but employing improvements in observational techniques it may now be possible not only to quantify but also to understand how different components of the atmosphere (e.g., concentration of gases, cloud cover, moisture, and aerosols) contribute to the greenhouse effect. Using weather balloons equipped with radiosondes, Philipona et al. continuously measured radiation fluxes from the surface of Earth up to altitudes of 35 kilometers in the upper stratosphere. Combining data from flights conducted during both day and night with continuous 24-hour measurements made at the surface of the Earth, the researchers created radiation profiles of all four components necessary to fully capture the radiation budget of Earth, namely, the upward and downward short-wave and long-wave radiation as a function of altitude.

  16. Quantifying meta-correlations in financial markets

    NASA Astrophysics Data System (ADS)

    Kenett, Dror Y.; Preis, Tobias; Gur-Gershgoren, Gitit; Ben-Jacob, Eshel

    2012-08-01

    Financial markets are modular multi-level systems, in which the relationships between the individual components are not constant in time. Sudden changes in these relationships significantly affect the stability of the entire system, and vice versa. Our analysis is based on historical daily closing prices of the 30 components of the Dow Jones Industrial Average (DJIA) from March 15th, 1939 until December 31st, 2010. We quantify the correlation among these components by determining Pearson correlation coefficients, to investigate whether mean correlation of the entire portfolio can be used as a precursor for changes in the index return. To this end, we quantify the meta-correlation - the correlation of mean correlation and index return. We find that changes in index returns are significantly correlated with changes in mean correlation. Furthermore, we study the relationship between the index return and correlation volatility - the standard deviation of correlations for a given time interval. This parameter provides further evidence of the effect of the index on market correlations and their fluctuations. Our empirical findings provide new information and quantification of the index leverage effect, and have implications to risk management, portfolio optimization, and to the increased stability of financial markets.

  17. Technology Transfer: A Selected Bibliography.

    ERIC Educational Resources Information Center

    Sovel, M. Terry

    This bibliography of 428 items, a product of the NASA-sponsored Project for the Analysis of Technology Transfer (PATT) at the University of Denver's Research Institute (DRI), is the initial attempt at compiling a comprehensive listing on the subject of technology transfer. The bibliography is further concerned with information which leads to a…

  18. Quantifying Transmission.

    PubMed

    Woolhouse, Mark

    2017-07-01

    Transmissibility is the defining characteristic of infectious diseases. Quantifying transmission matters for understanding infectious disease epidemiology and designing evidence-based disease control programs. Tracing individual transmission events can be achieved by epidemiological investigation coupled with pathogen typing or genome sequencing. Individual infectiousness can be estimated by measuring pathogen loads, but few studies have directly estimated the ability of infected hosts to transmit to uninfected hosts. Individuals' opportunities to transmit infection are dependent on behavioral and other risk factors relevant given the transmission route of the pathogen concerned. Transmission at the population level can be quantified through knowledge of risk factors in the population or phylogeographic analysis of pathogen sequence data. Mathematical model-based approaches require estimation of the per capita transmission rate and basic reproduction number, obtained by fitting models to case data and/or analysis of pathogen sequence data. Heterogeneities in infectiousness, contact behavior, and susceptibility can have substantial effects on the epidemiology of an infectious disease, so estimates of only mean values may be insufficient. For some pathogens, super-shedders (infected individuals who are highly infectious) and super-spreaders (individuals with more opportunities to transmit infection) may be important. Future work on quantifying transmission should involve integrated analyses of multiple data sources.

  19. Quantifying solute transport processes: are chemically "conservative" tracers electrically conservative?

    USGS Publications Warehouse

    Singha, Kamini; Li, Li; Day-Lewis, Frederick D.; Regberg, Aaron B.

    2012-01-01

    The concept of a nonreactive or conservative tracer, commonly invoked in investigations of solute transport, requires additional study in the context of electrical geophysical monitoring. Tracers that are commonly considered conservative may undergo reactive processes, such as ion exchange, thus changing the aqueous composition of the system. As a result, the measured electrical conductivity may reflect not only solute transport but also reactive processes. We have evaluated the impacts of ion exchange reactions, rate-limited mass transfer, and surface conduction on quantifying tracer mass, mean arrival time, and temporal variance in laboratory-scale column experiments. Numerical examples showed that (1) ion exchange can lead to resistivity-estimated tracer mass, velocity, and dispersivity that may be inaccurate; (2) mass transfer leads to an overestimate in the mobile tracer mass and an underestimate in velocity when using electrical methods; and (3) surface conductance does not notably affect estimated moments when high-concentration tracers are used, although this phenomenon may be important at low concentrations or in sediments with high and/or spatially variable cation-exchange capacity. In all cases, colocated groundwater concentration measurements are of high importance for interpreting geophysical data with respect to the controlling transport processes of interest.

  20. Optimal information transfer in enzymatic networks: A field theoretic formulation

    NASA Astrophysics Data System (ADS)

    Samanta, Himadri S.; Hinczewski, Michael; Thirumalai, D.

    2017-07-01

    Signaling in enzymatic networks is typically triggered by environmental fluctuations, resulting in a series of stochastic chemical reactions, leading to corruption of the signal by noise. For example, information flow is initiated by binding of extracellular ligands to receptors, which is transmitted through a cascade involving kinase-phosphatase stochastic chemical reactions. For a class of such networks, we develop a general field-theoretic approach to calculate the error in signal transmission as a function of an appropriate control variable. Application of the theory to a simple push-pull network, a module in the kinase-phosphatase cascade, recovers the exact results for error in signal transmission previously obtained using umbral calculus [Hinczewski and Thirumalai, Phys. Rev. X 4, 041017 (2014), 10.1103/PhysRevX.4.041017]. We illustrate the generality of the theory by studying the minimal errors in noise reduction in a reaction cascade with two connected push-pull modules. Such a cascade behaves as an effective three-species network with a pseudointermediate. In this case, optimal information transfer, resulting in the smallest square of the error between the input and output, occurs with a time delay, which is given by the inverse of the decay rate of the pseudointermediate. Surprisingly, in these examples the minimum error computed using simulations that take nonlinearities and discrete nature of molecules into account coincides with the predictions of a linear theory. In contrast, there are substantial deviations between simulations and predictions of the linear theory in error in signal propagation in an enzymatic push-pull network for a certain range of parameters. Inclusion of second-order perturbative corrections shows that differences between simulations and theoretical predictions are minimized. Our study establishes that a field theoretic formulation of stochastic biological signaling offers a systematic way to understand error propagation in

  1. Drivers of nitrogen transfer in stream food webs across continents

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Norman, Beth C.; Whiles, Matt R.; Collins, Sarah M.

    Studies of trophic-level material and energy transfers are central to ecology. The use of isotopic tracers has now made it possible to measure trophic transfer efficiencies of important nutrients and to better understand how these materials move through food webs. We analyzed data from thirteen 15N-ammonium tracer addition experiments to quantify N transfer from basal resources to animals in headwater streams with varying physical, chemical, and biological features. N transfer efficiencies from primary uptake compartments (PUCs; heterotrophic microorganisms and primary producers) to primary consumers was lower (mean: 11.5%, range: <1%-43%) than N transfer efficiencies from primary consumers to predators (mean:more » 80%, range: 5%- >100%). Total N transferred (as a rate) was greater in streams with open compared to closed canopies and overall N transfer efficiency generally followed a similar pattern, although was not statistically significant. We used principal component analysis to condense a suite of site characteristics into two environmental components. Total N uptake rates among trophic levels were best predicted by the component that was correlated with latitude, DIN:SRP, GPP:ER, and % canopy cover. N transfer efficiency did not respond consistently to environmental variables. Here, our results suggest that canopy cover influences N movement through stream food webs because light availability and primary production facilitate N transfer to higher trophic levels.« less

  2. Drivers of nitrogen transfer in stream food webs across continents

    DOE PAGES

    Norman, Beth C.; Whiles, Matt R.; Collins, Sarah M.; ...

    2017-10-25

    Studies of trophic-level material and energy transfers are central to ecology. The use of isotopic tracers has now made it possible to measure trophic transfer efficiencies of important nutrients and to better understand how these materials move through food webs. We analyzed data from thirteen 15N-ammonium tracer addition experiments to quantify N transfer from basal resources to animals in headwater streams with varying physical, chemical, and biological features. N transfer efficiencies from primary uptake compartments (PUCs; heterotrophic microorganisms and primary producers) to primary consumers was lower (mean: 11.5%, range: <1%-43%) than N transfer efficiencies from primary consumers to predators (mean:more » 80%, range: 5%- >100%). Total N transferred (as a rate) was greater in streams with open compared to closed canopies and overall N transfer efficiency generally followed a similar pattern, although was not statistically significant. We used principal component analysis to condense a suite of site characteristics into two environmental components. Total N uptake rates among trophic levels were best predicted by the component that was correlated with latitude, DIN:SRP, GPP:ER, and % canopy cover. N transfer efficiency did not respond consistently to environmental variables. Here, our results suggest that canopy cover influences N movement through stream food webs because light availability and primary production facilitate N transfer to higher trophic levels.« less

  3. Drivers of nitrogen transfer in stream food webs across continents.

    PubMed

    Norman, Beth C; Whiles, Matt R; Collins, Sarah M; Flecker, Alexander S; Hamilton, Steve K; Johnson, Sherri L; Rosi, Emma J; Ashkenas, Linda R; Bowden, William B; Crenshaw, Chelsea L; Crowl, Todd; Dodds, Walter K; Hall, Robert O; El-Sabaawi, Rana; Griffiths, Natalie A; Marti, Eugènia; McDowell, William H; Peterson, Scot D; Rantala, Heidi M; Riis, Tenna; Simon, Kevin S; Tank, Jennifer L; Thomas, Steven A; von Schiller, Daniel; Webster, Jackson R

    2017-12-01

    Studies of trophic-level material and energy transfers are central to ecology. The use of isotopic tracers has now made it possible to measure trophic transfer efficiencies of important nutrients and to better understand how these materials move through food webs. We analyzed data from thirteen 15 N-ammonium tracer addition experiments to quantify N transfer from basal resources to animals in headwater streams with varying physical, chemical, and biological features. N transfer efficiencies from primary uptake compartments (PUCs; heterotrophic microorganisms and primary producers) to primary consumers was lower (mean 11.5%, range <1% to 43%) than N transfer efficiencies from primary consumers to predators (mean 80%, range 5% to >100%). Total N transferred (as a rate) was greater in streams with open compared to closed canopies and overall N transfer efficiency generally followed a similar pattern, although was not statistically significant. We used principal component analysis to condense a suite of site characteristics into two environmental components. Total N uptake rates among trophic levels were best predicted by the component that was correlated with latitude, DIN:SRP, GPP:ER, and percent canopy cover. N transfer efficiency did not respond consistently to environmental variables. Our results suggest that canopy cover influences N movement through stream food webs because light availability and primary production facilitate N transfer to higher trophic levels. © 2017 by the Ecological Society of America.

  4. An Update on the Learning Transfer System

    ERIC Educational Resources Information Center

    Choi, Myungweon; Ruona, Wendy E. A.

    2008-01-01

    Learning transfer in organizations is a central issue in HRD. Much of the research of the 1980-1990's informed the development of the learning transfer system inventory (Holton, Bates, & Ruona, 2000). However, it's vitally important to continually enhance our understanding of the learning transfer system. In this paper, we reviewed the new…

  5. Percolation induced heat transfer in deep unsaturated zones

    USGS Publications Warehouse

    Lu, N.; LeCain, G.D.

    2003-01-01

    Subsurface temperature data from a borehole located in a desert wash were measured and used to delineate the conductive and advective heat transfer regimes, and to estimate the percolation quantity associated with the 1997-1998 El Ni??no precipitation. In an arid environment, conductive heat transfer dominates the variation of shallow subsurface temperature most of the time, except during sporadic precipitation periods. The subsurface time-varying temperature due to conductive heat transfer is highly correlated with the surface atmospheric temperature variation, whereas temperature variation due to advective heat transfer is strongly correlated with precipitation events. The advective heat transfer associated with precipitation and infiltration is the focus of this paper. Disruptions of the subsurface conductive temperature regime, associated with the 1997-1998 El Ni??no precipitation, were detected and used to quantify the percolation quantity. Modeling synthesis using a one-dimensional coupled heat and unsaturated flow model indicated that a percolation per unit area of 0.7 to 1.3 m height of water in two weeks during February 1998 was responsible for the observed temperature deviations down to a depth of 35.2 m. The reported study demonstrated quantitatively, for the first time, that the near surface temperature variation due to advective heat transfer can be significant at a depth greater than 10 m in unsaturated soils and can be used to infer the percolation amount in thick unsaturated soils.

  6. Incomplete Multisource Transfer Learning.

    PubMed

    Ding, Zhengming; Shao, Ming; Fu, Yun

    2018-02-01

    Transfer learning is generally exploited to adapt well-established source knowledge for learning tasks in weakly labeled or unlabeled target domain. Nowadays, it is common to see multiple sources available for knowledge transfer, each of which, however, may not include complete classes information of the target domain. Naively merging multiple sources together would lead to inferior results due to the large divergence among multiple sources. In this paper, we attempt to utilize incomplete multiple sources for effective knowledge transfer to facilitate the learning task in target domain. To this end, we propose an incomplete multisource transfer learning through two directional knowledge transfer, i.e., cross-domain transfer from each source to target, and cross-source transfer. In particular, in cross-domain direction, we deploy latent low-rank transfer learning guided by iterative structure learning to transfer knowledge from each single source to target domain. This practice reinforces to compensate for any missing data in each source by the complete target data. While in cross-source direction, unsupervised manifold regularizer and effective multisource alignment are explored to jointly compensate for missing data from one portion of source to another. In this way, both marginal and conditional distribution discrepancy in two directions would be mitigated. Experimental results on standard cross-domain benchmarks and synthetic data sets demonstrate the effectiveness of our proposed model in knowledge transfer from incomplete multiple sources.

  7. Quantifying learning in biotracer studies.

    PubMed

    Brown, Christopher J; Brett, Michael T; Adame, Maria Fernanda; Stewart-Koster, Ben; Bunn, Stuart E

    2018-04-12

    Mixing models have become requisite tools for analyzing biotracer data, most commonly stable isotope ratios, to infer dietary contributions of multiple sources to a consumer. However, Bayesian mixing models will always return a result that defaults to their priors if the data poorly resolve the source contributions, and thus, their interpretation requires caution. We describe an application of information theory to quantify how much has been learned about a consumer's diet from new biotracer data. We apply the approach to two example data sets. We find that variation in the isotope ratios of sources limits the precision of estimates for the consumer's diet, even with a large number of consumer samples. Thus, the approach which we describe is a type of power analysis that uses a priori simulations to find an optimal sample size. Biotracer data are fundamentally limited in their ability to discriminate consumer diets. We suggest that other types of data, such as gut content analysis, must be used as prior information in model fitting, to improve model learning about the consumer's diet. Information theory may also be used to identify optimal sampling protocols in situations where sampling of consumers is limited due to expense or ethical concerns.

  8. Altered transfer of visual motion information to parietal association cortex in untreated first-episode psychosis: Implications for pursuit eye tracking

    PubMed Central

    Lencer, Rebekka; Keedy, Sarah K.; Reilly, James L.; McDonough, Bruce E.; Harris, Margret S. H.; Sprenger, Andreas; Sweeney, John A.

    2011-01-01

    Visual motion processing and its use for pursuit eye movement control represent a valuable model for studying the use of sensory input for action planning. In psychotic disorders, alterations of visual motion perception have been suggested to cause pursuit eye tracking deficits. We evaluated this system in functional neuroimaging studies of untreated first-episode schizophrenia (N=24), psychotic bipolar disorder patients (N=13) and healthy controls (N=20). During a passive visual motion processing task, both patient groups showed reduced activation in the posterior parietal projection fields of motion-sensitive extrastriate area V5, but not in V5 itself. This suggests reduced bottom-up transfer of visual motion information from extrastriate cortex to perceptual systems in parietal association cortex. During active pursuit, activation was enhanced in anterior intraparietal sulcus and insula in both patient groups, and in dorsolateral prefrontal cortex and dorsomedial thalamus in schizophrenia patients. This may result from increased demands on sensorimotor systems for pursuit control due to the limited availability of perceptual motion information about target speed and tracking error. Visual motion information transfer deficits to higher -level association cortex may contribute to well-established pursuit tracking abnormalities, and perhaps to a wider array of alterations in perception and action planning in psychotic disorders. PMID:21873035

  9. Teacher Turnover: Examining Exit Attrition, Teaching Area Transfer, and School Migration

    ERIC Educational Resources Information Center

    Boe, Erling E.; Cook, Lynne H.; Sunderland, Robert J.

    2008-01-01

    The purposes of this research were to quantify trends in three components of teacher turnover and to investigate claims of excessive teacher turnover as the predominant source of teacher shortages. Attrition and teaching area transfer rates were comparable in special and general education and increased substantially from 1991-1992 to 2000-2001.…

  10. Juvenile hake predation on Myctophidae and Sternoptychidae: Quantifying an energy transfer between mesopelagic and neritic communities

    NASA Astrophysics Data System (ADS)

    Modica, Larissa; Cartes, Joan E.; Velasco, Francisco; Bozzano, Anna

    2015-01-01

    Seasonal study of the diet and food consumption of juvenile hake has been carried out in the Central Mediterranean Sea (Southern Tyrrhenian Sea). Fish were the most important food resource in terms of weight (ca. 70%). Among the fish, Myctophidae and Sternoptychidae, which are usually distributed deeper than juvenile hake, are most important. During summer, Ceratoscopelus maderensis constituted up to 21% of weight of all prey, and Maurolicus muelleri represented almost 10%. During autumn M. muelleri became the most important food resource. The way in which these more deeply distributed prey enter shallower food webs relates to the daily vertical migrations of lanternfish. In upper water column strata at night or near dawn they become prey of the juvenile hake. Considering that trophic energy flows primarily downward, in the direction of the productivity gradient, the observed flow of energy from deep strata into epipelagic layers could be considered an inverse energy transfer. Daily food consumption of juvenile hake ranged between 4.11 and 4.72% of the body wet-weight (BWW). The application of a square-root model allowed calculation of the fraction of this consumption derived by ingestion of the more deeply distributed mesopelagic fish. Between 11.6% and 17.8% of food consumption was sustained by this energy flow. Such information is useful for understanding the interaction between communities distributed in different depth ranges and to reinforce the idea that marine communities are open systems in which migratory movements can dramatically change the assumptions and results of mass-balance models.

  11. The burden and outcome of in utero transfers.

    PubMed

    Musson, Rebecca E; Harrison, Catherine M

    2016-05-01

    To quantify the number of intrauterine transfers (IUTs) arranged by Embrace Yorkshire and Humber Infant and Children's Transport Service and, to determine the outcome of when women delivered their babies, or when they were discharged following transfer. Identification of all IUTs Embrace arranged between January 1, 2011 and February 29, 2012 with data collection to determine delivery time or date of discharge. There were 623 IUT referrals with a mean time taken to arrange a transfer of 109 minutes. The mean distance of IUT was 42.5 miles, and the main reason for IUT request was capacity of referring unit. 247 (52%) women delivered during the same admission and 156 delivered within 48 hours of transfer. Of those undelivered, 111 (48.7%) were discharged within 48 hours. Fibronectin test was used in 51 patients. The IUT service provided by Embrace is busy, with significant demands on administrative staff time. Neonatal cot capacity and gestation are the main reasons for transfer. There is potentially a cohort of women who may not have benefitted from IUT. We suggest the use of obstetric expertise will enhance the service, while ongoing work looking at neonatal unit cot capacity problems continues. ©2015 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

  12. Frequency and Nature of Infectious Risk Moments During Acute Care Based on the INFORM Structured Classification Taxonomy.

    PubMed

    Clack, Lauren; Passerini, Simone; Wolfensberger, Aline; Sax, Hugo; Manser, Tanja

    2018-03-01

    OBJECTIVE In this study, we sought to establish a comprehensive inventory of infectious risk moments (IRMs), defined as seemingly innocuous yet frequently occurring care manipulations potentially resulting in transfer of pathogens to patients. We also aimed to develop and employ an observational taxonomy to quantify the frequency and nature of IRMs in acute-care settings. DESIGN Prospective observational study and establishment of observational taxonomy. SETTING Intensive care unit, general medical ward, and emergency ward of a university-affiliated hospital. PARTICIPANTS Healthcare workers (HCWs) METHODS Exploratory observations were conducted to identify IRMs, which were coded based on the surfaces involved in the transmission pathway to establish a structured taxonomy. Structured observations were performed using this taxonomy to quantify IRMs in all 3 settings. RESULTS Following 129.17 hours of exploratory observations, identified IRMs involved HCW hands, gloves, care devices, mobile objects, and HCW clothing and accessories. A structured taxonomy called INFORM (INFectiOus Risk Moment) was established to classify each IRM according to the source, vector, and endpoint of potential pathogen transfer. We observed 1,138 IRMs during 53.77 hours of structured observations (31.25 active care hours) for an average foundation of 42.8 IRMs per active care hour overall, and average densities of 34.9, 36.8, and 56.3 IRMs in the intensive care, medical, and emergency wards, respectively. CONCLUSIONS Hands and gloves remain among the most important contributors to the transfer of pathogens within the healthcare setting, but medical devices, mobile objects, invasive devices, and HCW clothing and accessories may also contribute to patient colonization and/or infection. The INFORM observational taxonomy and IRM inventory presented may benefit clinical risk assessment, training and education, and future research. Infect Control Hosp Epidemiol 2018;39:272-279.

  13. Gas transfer velocities measured at low wind speed over a lake

    USGS Publications Warehouse

    Crusius, John; Wanninkhof, R.

    2003-01-01

    The relationship between gas transfer velocity and wind speed was evaluated at low wind speeds by quantifying the rate of evasion of the deliberate tracer, SF6, from a small oligotrophic lake. Several possible relationships between gas transfer velocity and low wind speed were evaluated by using 1-min-averaged wind speeds as a measure of the instantaneous wind speed values. Gas transfer velocities in this data set can be estimated virtually equally well by assuming any of three widely used relationships between k600 and winds referenced to 10-m height, U10: (1) a bilinear dependence with a break in the slope at ???3.7 m s-1, which resulted in the best fit; (2) a power dependence; and (3) a constant transfer velocity for U10 3.7 m s-1 which, coupled with the typical variability in instantaneous wind speeds observed in the field, leads to average transfer velocity estimates that are higher than those predicted for steady wind trends. The transfer velocities predicted by the bilinear steady wind relationship for U10 < ???3.7 m s-1 are virtually identical to the theoretical predictions for transfer across a smooth surface.

  14. Coupling of replisome movement with nucleosome dynamics can contribute to the parent-daughter information transfer.

    PubMed

    Bameta, Tripti; Das, Dibyendu; Padinhateeri, Ranjith

    2018-06-01

    Positioning of nucleosomes along the genomic DNA is crucial for many cellular processes that include gene regulation and higher order packaging of chromatin. The question of how nucleosome-positioning information from a parent chromatin gets transferred to the daughter chromatin is highly intriguing. Accounting for experimentally known coupling between replisome movement and nucleosome dynamics, we propose a model that can obtain de novo nucleosome assembly similar to what is observed in recent experiments. Simulating nucleosome dynamics during replication, we argue that short pausing of the replication fork, associated with nucleosome disassembly, can be a event crucial for communicating nucleosome positioning information from parent to daughter. We show that the interplay of timescales between nucleosome disassembly (τp) at the replication fork and nucleosome sliding behind the fork (τs) can give rise to a rich 'phase diagram' having different inherited patterns of nucleosome organization. Our model predicts that only when τp ≥ τs the daughter chromatin can inherit nucleosome positioning of the parent.

  15. On Quantifying Diffusion of Health Information on Twitter.

    PubMed

    Bakal, Gokhan; Kavuluru, Ramakanth

    2017-02-01

    With the increasing use of digital technologies, online social networks are emerging as major means of communication. Recently, social networks such as Facebook and Twitter are also being used by consumers, care providers (physicians, hospitals), and government agencies to share health related information. The asymmetric user network and the short message size have made Twitter particularly popular for propagating health related content on the Web. Besides tweeting on their own, users can choose to retweet particular tweets from other users (even if they do not follow them on Twitter.) Thus, a tweet can diffuse through the Twitter network via the follower-friend connections. In this paper, we report results of a pilot study we conducted to quantitatively assess how health related tweets diffuse in the directed follower-friend Twitter graph through the retweeting activity. Our effort includes (1). development of a retweet collection and Twitter retweet graph formation framework and (2). a preliminary analysis of retweet graphs and associated diffusion metrics for health tweets. Given the ambiguous nature (due to polysemy and sarcasm) of health relatedness of tweets collected with keyword based matches, our initial study is limited to ≈ 200 health related tweets (which were manually verified to be on health topics) each with at least 25 retweets. To our knowledge, this is first attempt to study health information diffusion on Twitter through retweet graph analysis.

  16. Critical Zone Co-dynamics: Quantifying Interactions between Subsurface, Land Surface, and Vegetation Properties Using UAV and Geophysical Approaches

    NASA Astrophysics Data System (ADS)

    Dafflon, B.; Leger, E.; Peterson, J.; Falco, N.; Wainwright, H. M.; Wu, Y.; Tran, A. P.; Brodie, E.; Williams, K. H.; Versteeg, R.; Hubbard, S. S.

    2017-12-01

    Improving understanding and modelling of terrestrial systems requires advances in measuring and quantifying interactions among subsurface, land surface and vegetation processes over relevant spatiotemporal scales. Such advances are important to quantify natural and managed ecosystem behaviors, as well as to predict how watershed systems respond to increasingly frequent hydrological perturbations, such as droughts, floods and early snowmelt. Our study focuses on the joint use of UAV-based multi-spectral aerial imaging, ground-based geophysical tomographic monitoring (incl., electrical and electromagnetic imaging) and point-scale sensing (soil moisture sensors and soil sampling) to quantify interactions between above and below ground compartments of the East River Watershed in the Upper Colorado River Basin. We evaluate linkages between physical properties (incl. soil composition, soil electrical conductivity, soil water content), metrics extracted from digital surface and terrain elevation models (incl., slope, wetness index) and vegetation properties (incl., greenness, plant type) in a 500 x 500 m hillslope-floodplain subsystem of the watershed. Data integration and analysis is supported by numerical approaches that simulate the control of soil and geomorphic characteristic on hydrological processes. Results provide an unprecedented window into critical zone interactions, revealing significant below- and above-ground co-dynamics. Baseline geophysical datasets provide lithological structure along the hillslope, which includes a surface soil horizon, underlain by a saprolite layer and the fractured Mancos shale. Time-lapse geophysical data show very different moisture dynamics in various compartments and locations during the winter and growing season. Integration with aerial imaging reveals a significant linkage between plant growth and the subsurface wetness, soil characteristics and the topographic gradient. The obtained information about the organization and

  17. Virtual groundwater transfers from overexploited aquifers in the United States

    PubMed Central

    Marston, Landon; Konar, Megan; Cai, Ximing; Troy, Tara J.

    2015-01-01

    The High Plains, Mississippi Embayment, and Central Valley aquifer systems within the United States are currently being overexploited for irrigation water supplies. The unsustainable use of groundwater resources in all three aquifer systems intensified from 2000 to 2008, making it imperative that we understand the consumptive processes and forces of demand that are driving their depletion. To this end, we quantify and track agricultural virtual groundwater transfers from these overexploited aquifer systems to their final destination. Specifically, we determine which US metropolitan areas, US states, and international export destinations are currently the largest consumers of these critical aquifers. We draw upon US government data on agricultural production, irrigation, and domestic food flows, as well as modeled estimates of agricultural virtual water contents to quantify domestic transfers. Additionally, we use US port-level trade data to trace international exports from these aquifers. In 2007, virtual groundwater transfers from the High Plains, Mississippi Embayment, and Central Valley aquifer systems totaled 17.93 km3, 9.18 km3, and 6.81 km3, respectively, which is comparable to the capacity of Lake Mead (35.7 km3), the largest surface reservoir in the United States. The vast majority (91%) of virtual groundwater transfers remains within the United States. Importantly, the cereals produced by these overexploited aquifers are critical to US food security (contributing 18.5% to domestic cereal supply). Notably, Japan relies upon cereals produced by these overexploited aquifers for 9.2% of its domestic cereal supply. These results highlight the need to understand the teleconnections between distant food demands and local agricultural water use. PMID:26124137

  18. Kinetics of conjugative gene transfer on surfaces in granular porous media

    NASA Astrophysics Data System (ADS)

    Massoudieh, A.; Crain, C.; Lambertini, E.; Nelson, K. E.; Barkouki, T.; L'Amoreaux, P.; Loge, F. J.; Ginn, T. R.

    2010-03-01

    The transfer of genetic material among bacteria in the environment can occur both in the planktonic and attached state. Given the propensity of organisms to exist in sessile microbial communities in oligotrophic subsurface conditions, and that such conditions typify the subsurface, this study focuses on exploratory modeling of horizontal gene transfer among surface-associated Escherichiacoli in the subsurface. The mathematics so far used to describe the kinetics of conjugation in biofilms are developed largely from experimental observations of planktonic gene transfer, and are absent of lags or plasmid stability that appear experimentally. We develop a model and experimental system to quantify bacterial filtration and gene transfer in the attached state, on granular porous media. We include attachment kinetics described in Nelson et al. (2007) using the filtration theory approach of Nelson and Ginn (2001, 2005) with motility of E. coli described according to Biondi et al. (1998).

  19. Extensor indicis proprius tendon transfer using shear wave elastography.

    PubMed

    Lamouille, J; Müller, C; Aubry, S; Bensamoun, S; Raffoul, W; Durand, S

    2017-06-01

    The means for judging optimal tension during tendon transfers are approximate and not very quantifiable. The purpose of this study was to demonstrate the feasibility of quantitatively assessing muscular mechanical properties intraoperatively using ultrasound elastography (shear wave elastography [SWE]) during extensor indicis proprius (EIP) transfer. We report two cases of EIP transfer for post-traumatic rupture of the extensor pollicis longus muscle. Ultrasound acquisitions measured the elasticity modulus of the EIP muscle at different stages: rest, active extension, active extension against resistance, EIP section, distal passive traction of the tendon, after tendon transfer at rest and then during active extension. A preliminary analysis was conducted of the distribution of values for this modulus at the various transfer steps. Different shear wave velocity and elasticity modulus values were observed at the various transfer steps. The tension applied during the transfer seemed close to the resting tension if a traditional protocol were followed. The elasticity modulus varied by a factor of 37 between the active extension against resistance step (565.1 kPa) and after the tendon section (15.3 kPa). The elasticity modulus values were distributed in the same way for each patient. The therapeutic benefit of SWE elastography was studied for the first time in tendon transfers. Quantitative data on the elasticity modulus during this test may make it an effective means of improving intraoperative adjustments. Copyright © 2017 SFCM. Published by Elsevier Masson SAS. All rights reserved.

  20. Extracting Spectroscopic Factors of Argon Isotopes from Transfer Reactions

    NASA Astrophysics Data System (ADS)

    Manfredi, Juan; Tsang, M. B.; Lynch, W. G.; Brown, K. W.; Cerizza, G.; Barney, J.; Estee, J.; Loelius, C.; Sweany, S.; Anderson, C.; Setiawan, H.; Winkelbauer, J.; Smith, K.; Lee, J.; Xu, Z.; Rogers, A.; Pruitt, C.; Chajecki, Z.; Chen, G.; Langer, C.; Xiao, Z.; Li, Z.; Niu, C.

    2017-09-01

    A spectroscopic factor (SF) quantifies the single particle structure of a given state in a nucleus. There is a discrepancy in extracted SF's between studies that use transfer reactions and those that use knockout reactions. Resolving this discrepancy is important both for understanding reaction probes as well as constraining nuclear structure theory. Kinematically complete measurements of the transfer reactions 34Ar(p,d) and 46Ar(p,d) were performed at the National Superconducting Cyclotron Laboratory. The same beam energy (70 MeV/u) was used as in a previous knockout measurement to account for energy dependence in the relevant optical potentials. Preliminary results will be presented. In addition, findings from measurement of the two-neutron transfer reactions 34Ar(p,t) and 4 6 Ar(p,t) will be discussed. This work was supported by the NSF (PHY 1565546) and the DOE NNSA Stewardship Science Graduate Fellowship.

  1. Design of Instrument Approach Procedure Charts Comprehension Speed of Missed Approach Instructions Coded in Text or Icons

    DOT National Transportation Integrated Search

    1992-02-01

    Instrument approach procedure (IAP) charts are often cluttered and confusing. The quantified effects of chart design : changes on information transfer are needed by chart manufacturers to make changes uhich will enhance information transfer : and hum...

  2. Entanglement transfer from microwaves to diamond NV centers

    NASA Astrophysics Data System (ADS)

    Gomez, Angela V.; Rodriguez, Ferney J.; Quiroga, Luis

    2014-03-01

    Strong candidates to create quantum entangled states in solid-state environments are the nitrogen-vacancy (NV) defect centers in diamond. By the combination of radiation from different wavelength (optical, microwave and radio-frequency), several protocols have been proposed to create entangled states of different NVs. Recently, experimental sources of non-classical microwave radiation have been successfully realized. Here, we consider the entanglement transfer from spatially separated two-mode microwave squeezed (entangled) photons to a pair of NV centers by exploiting the fact that the spin triplet ground state of a NV has a natural splitting with a frequency on the order of GHz (microwave range). We first demonstrate that the transfer process in the simplest case of a single pair of spatially separated NVs is feasible. Moreover, we proceed to extend the previous results to more realistic scenarios where 13C nuclear spin baths surrounding each NV are included, quantifying the degradation of the entanglement transfer by the dephasing/dissipation effects produced by the nuclear baths. Finally, we address the issue of assessing the possibility of entanglement transfer from the squeezed microwave light to two nuclear spins closely linked to different NV center electrons. Facultad de Ciencias Uniandes.

  3. Evaluating disparities in the U.S. technology transfer ecosystem to improve bench to business translation.

    PubMed

    Weis, James; Bashyam, Ashvin; Ekchian, Gregory J; Paisner, Kathryn; Vanderford, Nathan L

    2018-01-01

    Background: A large number of highly impactful technologies originated from academic research, and the transfer of inventions from academic institutions to private industry is a major driver of economic growth, and a catalyst for further discovery. However, there are significant inefficiencies in academic technology transfer. In this work, we conducted a data-driven assessment of translational activity across United States (U.S.) institutions to better understand how effective universities are in facilitating the transfer of new technologies into the marketplace. From this analysis, we provide recommendations to guide technology transfer policy making at both the university and national level. Methods: Using data from the Association of University Technology Managers U.S. Licensing Activity Survey, we defined a commercialization pipeline that reflects the typical path intellectual property takes; from initial research funding to startup formation and gross income. We use this pipeline to quantify the performance of academic institutions at each step of the process, as well as overall, and identify the top performing institutions via mean reciprocal rank. The corresponding distributions were visualized and disparities quantified using the Gini coefficient. Results: We found significant discrepancies in commercialization activity between institutions; a small number of institutions contribute to the vast majority of total commercialization activity. By examining select top performing institutions, we suggest improvements universities and technology transfer offices could implement to emulate the environment at these high-performing institutions. Conclusion: Significant disparities in technology transfer performance exist in which a select set of institutions produce a majority share of the total technology transfer activity. This disparity points to missed commercialization opportunities, and thus, further investigation into the distribution of technology transfer

  4. Evaluating disparities in the U.S. technology transfer ecosystem to improve bench to business translation

    PubMed Central

    Paisner, Kathryn; Vanderford, Nathan L.

    2018-01-01

    Background: A large number of highly impactful technologies originated from academic research, and the transfer of inventions from academic institutions to private industry is a major driver of economic growth, and a catalyst for further discovery. However, there are significant inefficiencies in academic technology transfer. In this work, we conducted a data-driven assessment of translational activity across United States (U.S.) institutions to better understand how effective universities are in facilitating the transfer of new technologies into the marketplace. From this analysis, we provide recommendations to guide technology transfer policy making at both the university and national level. Methods: Using data from the Association of University Technology Managers U.S. Licensing Activity Survey, we defined a commercialization pipeline that reflects the typical path intellectual property takes; from initial research funding to startup formation and gross income. We use this pipeline to quantify the performance of academic institutions at each step of the process, as well as overall, and identify the top performing institutions via mean reciprocal rank. The corresponding distributions were visualized and disparities quantified using the Gini coefficient. Results: We found significant discrepancies in commercialization activity between institutions; a small number of institutions contribute to the vast majority of total commercialization activity. By examining select top performing institutions, we suggest improvements universities and technology transfer offices could implement to emulate the environment at these high-performing institutions. Conclusion: Significant disparities in technology transfer performance exist in which a select set of institutions produce a majority share of the total technology transfer activity. This disparity points to missed commercialization opportunities, and thus, further investigation into the distribution of technology transfer

  5. Breakdown of local information processing may underlie isoflurane anesthesia effects.

    PubMed

    Wollstadt, Patricia; Sellers, Kristin K; Rudelt, Lucas; Priesemann, Viola; Hutt, Axel; Fröhlich, Flavio; Wibral, Michael

    2017-06-01

    The disruption of coupling between brain areas has been suggested as the mechanism underlying loss of consciousness in anesthesia. This hypothesis has been tested previously by measuring the information transfer between brain areas, and by taking reduced information transfer as a proxy for decoupling. Yet, information transfer is a function of the amount of information available in the information source-such that transfer decreases even for unchanged coupling when less source information is available. Therefore, we reconsidered past interpretations of reduced information transfer as a sign of decoupling, and asked whether impaired local information processing leads to a loss of information transfer. An important prediction of this alternative hypothesis is that changes in locally available information (signal entropy) should be at least as pronounced as changes in information transfer. We tested this prediction by recording local field potentials in two ferrets after administration of isoflurane in concentrations of 0.0%, 0.5%, and 1.0%. We found strong decreases in the source entropy under isoflurane in area V1 and the prefrontal cortex (PFC)-as predicted by our alternative hypothesis. The decrease in source entropy was stronger in PFC compared to V1. Information transfer between V1 and PFC was reduced bidirectionally, but with a stronger decrease from PFC to V1. This links the stronger decrease in information transfer to the stronger decrease in source entropy-suggesting reduced source entropy reduces information transfer. This conclusion fits the observation that the synaptic targets of isoflurane are located in local cortical circuits rather than on the synapses formed by interareal axonal projections. Thus, changes in information transfer under isoflurane seem to be a consequence of changes in local processing more than of decoupling between brain areas. We suggest that source entropy changes must be considered whenever interpreting changes in information

  6. Breakdown of local information processing may underlie isoflurane anesthesia effects

    PubMed Central

    Sellers, Kristin K.; Priesemann, Viola; Hutt, Axel

    2017-01-01

    The disruption of coupling between brain areas has been suggested as the mechanism underlying loss of consciousness in anesthesia. This hypothesis has been tested previously by measuring the information transfer between brain areas, and by taking reduced information transfer as a proxy for decoupling. Yet, information transfer is a function of the amount of information available in the information source—such that transfer decreases even for unchanged coupling when less source information is available. Therefore, we reconsidered past interpretations of reduced information transfer as a sign of decoupling, and asked whether impaired local information processing leads to a loss of information transfer. An important prediction of this alternative hypothesis is that changes in locally available information (signal entropy) should be at least as pronounced as changes in information transfer. We tested this prediction by recording local field potentials in two ferrets after administration of isoflurane in concentrations of 0.0%, 0.5%, and 1.0%. We found strong decreases in the source entropy under isoflurane in area V1 and the prefrontal cortex (PFC)—as predicted by our alternative hypothesis. The decrease in source entropy was stronger in PFC compared to V1. Information transfer between V1 and PFC was reduced bidirectionally, but with a stronger decrease from PFC to V1. This links the stronger decrease in information transfer to the stronger decrease in source entropy—suggesting reduced source entropy reduces information transfer. This conclusion fits the observation that the synaptic targets of isoflurane are located in local cortical circuits rather than on the synapses formed by interareal axonal projections. Thus, changes in information transfer under isoflurane seem to be a consequence of changes in local processing more than of decoupling between brain areas. We suggest that source entropy changes must be considered whenever interpreting changes in

  7. A novel approach to quantify cybersecurity for electric power systems

    NASA Astrophysics Data System (ADS)

    Kaster, Paul R., Jr.

    Electric Power grid cybersecurity is a topic gaining increased attention in academia, industry, and government circles, yet a method of quantifying and evaluating a system's security is not yet commonly accepted. In order to be useful, a quantification scheme must be able to accurately reflect the degree to which a system is secure, simply determine the level of security in a system using real-world values, model a wide variety of attacker capabilities, be useful for planning and evaluation, allow a system owner to publish information without compromising the security of the system, and compare relative levels of security between systems. Published attempts at quantifying cybersecurity fail at one or more of these criteria. This document proposes a new method of quantifying cybersecurity that meets those objectives. This dissertation evaluates the current state of cybersecurity research, discusses the criteria mentioned previously, proposes a new quantification scheme, presents an innovative method of modeling cyber attacks, demonstrates that the proposed quantification methodology meets the evaluation criteria, and proposes a line of research for future efforts.

  8. Efficient Transfer Entropy Analysis of Non-Stationary Neural Time Series

    PubMed Central

    Vicente, Raul; Díaz-Pernas, Francisco J.; Wibral, Michael

    2014-01-01

    Information theory allows us to investigate information processing in neural systems in terms of information transfer, storage and modification. Especially the measure of information transfer, transfer entropy, has seen a dramatic surge of interest in neuroscience. Estimating transfer entropy from two processes requires the observation of multiple realizations of these processes to estimate associated probability density functions. To obtain these necessary observations, available estimators typically assume stationarity of processes to allow pooling of observations over time. This assumption however, is a major obstacle to the application of these estimators in neuroscience as observed processes are often non-stationary. As a solution, Gomez-Herrero and colleagues theoretically showed that the stationarity assumption may be avoided by estimating transfer entropy from an ensemble of realizations. Such an ensemble of realizations is often readily available in neuroscience experiments in the form of experimental trials. Thus, in this work we combine the ensemble method with a recently proposed transfer entropy estimator to make transfer entropy estimation applicable to non-stationary time series. We present an efficient implementation of the approach that is suitable for the increased computational demand of the ensemble method's practical application. In particular, we use a massively parallel implementation for a graphics processing unit to handle the computationally most heavy aspects of the ensemble method for transfer entropy estimation. We test the performance and robustness of our implementation on data from numerical simulations of stochastic processes. We also demonstrate the applicability of the ensemble method to magnetoencephalographic data. While we mainly evaluate the proposed method for neuroscience data, we expect it to be applicable in a variety of fields that are concerned with the analysis of information transfer in complex biological, social, and

  9. Orbital transfer vehicle studies overview

    NASA Technical Reports Server (NTRS)

    Perkinson, Don

    1987-01-01

    An overview is given in viewgraph form of orbital transfer vehicle concept definition and systems analysis studies. Project development flow charts are shown for key milestones from 1985 until 1997. Diagrams of vehicles are given. Information is presented in outline form on technology requirements, cooling of propellant tanks, cryogenic fluid management, quick connect/disconnect fluid interfaces and propellant mass transfer.

  10. Flight Simulation for the Study of Skill Transfer.

    ERIC Educational Resources Information Center

    Lintern, Gavan

    1992-01-01

    Discusses skill transfer as a human performance issue based on experiences with computerized flight simulators. Highlights include the issue of similarity; simulation and the design of training devices; an information theory of transfer; invariants for flight control; and experiments involving the transfer of flight skills. (21 references) (LRW)

  11. Cost benefit assessment of NASA remote sensing technology transferred to the State of Georgia

    NASA Technical Reports Server (NTRS)

    Kelly, D. L.; Zimmer, R. P.; Wilkins, R. D.

    1978-01-01

    The benefits involved in the transfer of NASA remote sensing technology to eight Georgia state agencies are identified in quantifiable and qualitative terms, and a value for these benefits is computed by means of an effectiveness analysis. The benefits of the transfer are evaluated by contrasting a baseline scenario without Landsat and an alternative scenario with Landsat. The net present value of the Landsat technology being transferred is estimated at 9.5 million dollars. The estimated value of the transfer is most sensitive to discount rate, the cost of photo acquisition, and the cost of data digitalization. It is estimated that, if the budget is constrained, Landsat could provide data products roughly seven times more frequently than would otherwise be possible.

  12. FIBRE AND INTEGRATED OPTICS. OPTICAL PROCESSING OF INFORMATION: Feasibility of using waveguide holograms in systems for the transfer of amplitude—phase information along fibre communication lines

    NASA Astrophysics Data System (ADS)

    Dianov, Evgenii M.; Zubov, Vladimir A.; Putilin, A. N.

    1995-02-01

    An analysis is made of a variant of a system for spatial—temporal transformation of spatially one-dimensional information for its transfer along a single-mode fibre waveguide. Information is coupled into a fibre by a waveguide hologram. This hologram forms a light-beam structure which matches the fibre-guided mode. A report is given of the use of ion-exchange planar glass waveguides as waveguide holograms. An amorphous chalcogenide semiconductor film or a photoresist was deposited by evaporation on such a planar waveguide. Reconstruction of the waveguide hologram made it possible to achieve a high read rate, up to 1011 pixels per second, when a short radiation pulse was used. Multisectioned injection semiconductor lasers, operating under Q-switching conditions, were used as the radiation sources.

  13. Proton transfer in microbial electrolysis cells

    DOE PAGES

    Borole, Abhijeet P.; Lewis, Alex J.

    2017-02-15

    Proton transfer and electron transfer are of prime importance in the development of microbial electrochemical cells. While electron transfer is primarily controlled by biology, proton transfer is controlled by process engineering and cell design. To develop commercially feasible technologies around the concept of a bioelectrochemical cell, real feedstocks have to be explored and associated limitations have to be identified. Here in this study, the proton transfer rate was quantified for a microbial electrolysis cell (MEC) and its dependence on process parameters was investigated using a proton balance model. The reaction system consisted of a biomass-derived pyrolytic aqueous stream as amore » substrate producing hydrogen in a flow-through MEC. The proton transfer rate increased with anode flow rate and organic loading rate up to a maximum of 0.36 ± 0.01 moles per m 2 per h, equivalent to a hydrogen production rate of 9.08 L per L per day. Higher rates of hydrogen production, reaching 11.7 ± 0.2 L per L per day were achieved, when additional protons were provided via the cathode buffer. Electrochemical impedance spectroscopy shows that proton transfer was the dominant resistance in the production of hydrogen. The quantification of proton transfer rates for MECs with potential for biorefinery application and the demonstration of high hydrogen production rates approaching those required for commercial consideration indicate the strong potential of this technology for renewable hydrogen production. Understanding the transport phenomenon in bioelectrochemical cells is of great significance since these systems have potential for wide-ranging applications including energy production, bioremediation, chemical and nanomaterial synthesis, electro-fermentation, energy storage, desalination, and produced water treatment. Electron transfer in anode biofilms has been investigated extensively, but proton transfer studies are also important, since many cathodic half reactions

  14. Proton transfer in microbial electrolysis cells

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Borole, Abhijeet P.; Lewis, Alex J.

    Proton transfer and electron transfer are of prime importance in the development of microbial electrochemical cells. While electron transfer is primarily controlled by biology, proton transfer is controlled by process engineering and cell design. To develop commercially feasible technologies around the concept of a bioelectrochemical cell, real feedstocks have to be explored and associated limitations have to be identified. Here in this study, the proton transfer rate was quantified for a microbial electrolysis cell (MEC) and its dependence on process parameters was investigated using a proton balance model. The reaction system consisted of a biomass-derived pyrolytic aqueous stream as amore » substrate producing hydrogen in a flow-through MEC. The proton transfer rate increased with anode flow rate and organic loading rate up to a maximum of 0.36 ± 0.01 moles per m 2 per h, equivalent to a hydrogen production rate of 9.08 L per L per day. Higher rates of hydrogen production, reaching 11.7 ± 0.2 L per L per day were achieved, when additional protons were provided via the cathode buffer. Electrochemical impedance spectroscopy shows that proton transfer was the dominant resistance in the production of hydrogen. The quantification of proton transfer rates for MECs with potential for biorefinery application and the demonstration of high hydrogen production rates approaching those required for commercial consideration indicate the strong potential of this technology for renewable hydrogen production. Understanding the transport phenomenon in bioelectrochemical cells is of great significance since these systems have potential for wide-ranging applications including energy production, bioremediation, chemical and nanomaterial synthesis, electro-fermentation, energy storage, desalination, and produced water treatment. Electron transfer in anode biofilms has been investigated extensively, but proton transfer studies are also important, since many cathodic half reactions

  15. EXPERIMENTAL METHODOLOGIES AND PRELIMINARY TRANSFER FACTOR DATA FOR ESTIMATION OF DERMAL EXPOSURES TO PARTICLES

    EPA Science Inventory

    Developmental efforts and experimental data are described that focused on quantifying the transfer of particles on a mass basis from indoor surfaces to human skin. Methods were developed that utilized a common fluorescein-tagged Arizona Test Dust (ATD) as a possible surrogate ...

  16. Comparison of transfer entropy methods for financial time series

    NASA Astrophysics Data System (ADS)

    He, Jiayi; Shang, Pengjian

    2017-09-01

    There is a certain relationship between the global financial markets, which creates an interactive network of global finance. Transfer entropy, a measurement for information transfer, offered a good way to analyse the relationship. In this paper, we analysed the relationship between 9 stock indices from the U.S., Europe and China (from 1995 to 2015) by using transfer entropy (TE), effective transfer entropy (ETE), Rényi transfer entropy (RTE) and effective Rényi transfer entropy (ERTE). We compared the four methods in the sense of the effectiveness for identification of the relationship between stock markets. In this paper, two kinds of information flows are given. One reveals that the U.S. took the leading position when in terms of lagged-current cases, but when it comes to the same date, China is the most influential. And ERTE could provide superior results.

  17. 28 CFR 22.24 - Information transfer agreement.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... information has already been included in research findings (and/or data bases) and is revealed on a need-to... into which shall provide, as a minimum, that the recipient of data agrees that: (a) Information... whom information relates, including, where appropriate, required name-stripping and/or coding of data...

  18. 28 CFR 22.24 - Information transfer agreement.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... information has already been included in research findings (and/or data bases) and is revealed on a need-to... into which shall provide, as a minimum, that the recipient of data agrees that: (a) Information... whom information relates, including, where appropriate, required name-stripping and/or coding of data...

  19. 28 CFR 22.24 - Information transfer agreement.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... information has already been included in research findings (and/or data bases) and is revealed on a need-to... into which shall provide, as a minimum, that the recipient of data agrees that: (a) Information... whom information relates, including, where appropriate, required name-stripping and/or coding of data...

  20. 28 CFR 22.24 - Information transfer agreement.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... information has already been included in research findings (and/or data bases) and is revealed on a need-to... into which shall provide, as a minimum, that the recipient of data agrees that: (a) Information... whom information relates, including, where appropriate, required name-stripping and/or coding of data...

  1. Quantification of blood-to-brain transfer rate in multiple sclerosis

    PubMed Central

    Taheri, Saeid; Rosenberg, Gary A.; Ford, Corey

    2016-01-01

    Blood–brain barrier (BBB) disruption visualized in lesions by MRI is a major biomarker of disease activity in multiple sclerosis (MS). However, in MS, destruction occurs to a variable extent in lesions as well as in gray matter (GM) and in the normal appearing white matter (NAWM). A method to quantify the BBB disruption in lesions as well as in non-lesion areas would be useful for assessment of MS progression and treatments. The objective of this study was to quantify the BBB transfer rate (Ki) in WM lesions, in the NAWM, and in the full-brain of MS patients. Thirteen MS patients with active lesions and 10 healthy controls with age and gender matching were recruited for full-brain and WM Ki studies. Dynamic contrast-enhanced MRI (DCEMRI) scans were conducted using T1 mapping with partial inversion recovery (TAPIR), a fast T1 mapping technique, following administration of a quarter-dose of the contrast agent Gadolinium-DTPA (Gd-DTPA). The Patlak modeling technique was used to derive a voxel-based map of Ki. In all patients contrast-enhanced lesions, quantified by Ki maps, were observed. Compared with controls, patients with MS exhibited an increase in mean Ki of the full-brain (P-value<0.05) but no significant difference in mean Ki of NAWM. The identified increase in full-brain Ki of MS patients suggests a global vascular involvement associated with MS disease. The lack of observed significant decrease in Ki in NAWM suggests lower involvement of WM vasculature than full-brain vasculature in MS. Ki maps constructed from time series data acquired by DCEMRI provide additional information about BBB that could be used for evaluation of vascular involvement in MS and monitoring treatment effectiveness. PMID:25877634

  2. Quantifying forest LAI succession in sub-tropical forests using time-series of Landsat data, 1987 -2015

    NASA Astrophysics Data System (ADS)

    Wu, Q.; Song, J.; Wang, J.; Chen, S.; Yu, B.; Liao, L.

    2016-12-01

    Monitoring the dynamics of leaf area index (LAI) throughout the life-cycle of forests (from seeding to maturity) is vital for simulating forest growth and quantifying carbon sequestration. However, all current global LAI produts show extremely low accuracy in forests and the coarse spatial resolution(nearly 1-km) mismatch with the spatial scale of forest inventory plots (nearly 26m*26m). To date, several studies have explored the possibility of satellite data to classify forest succession or predict stand age. And a few studies have explored the potential of using long term Landsat data to monitor the growing trend of forests, but no studies have quantified the inter-annual and intra-annual LAI dynamics along with forest succession. Vegetation indexes are not perfect variables in quantifying forest foliage dynamics. Hallet (1995) suggested remote sensing of biophysical characteristics should shift away from direct inference from vegetation indices toward more physically based algorithms. This work intends to be a pioneer example for improving the accuracy of forests LAI and providing temporal-spatial matching LAI datasets for monitoring forest processes. We integrates the Geometric-Optical and Radiative Transfer (GORT) model with the Physiological Principles Predicting Growth (3-PG) model to improve the estimation of the forest canopy LAI dynamics. Reflectance time-series data from 1987 to 2015 were collected and preprocessed for forests in southern China, using all available Landsat data (with <80% cloud). Effective LAI and true LAI were field measured to validate our results using various instruments, including digital hemispheric photographs (DHP), LAI-2000 Plant Canopy Analyzer (LI-COR), and Tracing radiation and Architecture of Canopies (TRAC). Results show that the relationship between spectral metrics of satellite images and forest LAI is clear in early stages before maturity. 3-PG provide accurate inter-annual trend of forest LAI, while satellite images

  3. Anode energy transfer in a transient arc

    NASA Astrophysics Data System (ADS)

    Valensi, F.; Ratovoson, P.; Razafinimanana, M.; Gleizes, A.

    2017-04-01

    This work deals with experimental investigation of a transient arc. Arc configuration and electrode erosion were studied in order to quantify the energy transfer to the electrodes as a function of maximal current, time constant and electrodes material. Experiments with two consecutive arcs allow demonstrating non stationary behaviour of the arc electrode interaction. This is due to the fact that while the duration of the experiments is far larger than plasma phenomena time constants, it is comparable to those of electrode heating and melting processes.

  4. The transfer instability index: a novel metric of emergency department transfer relationships.

    PubMed

    Kindermann, Dana R; Mutter, Ryan L; Houchens, Robert L; Barrett, Marguerite L; Pines, Jesse M

    2015-02-01

    In this study, the objective was to characterize emergency department (ED) transfer relationships and study the factors that predict the stability of those relationships. A metric is derived for ED transfer relationships that may be useful in assessing emergency care regionalization and as a resource for future emergency medicine research. Emergency department records at transferring hospitals were linked to ED and inpatient records at receiving hospitals in nine U.S. states using the 2010 Healthcare Cost and Utilization Project State Emergency Department Databases and State Inpatient Databases, the American Hospital Association Annual Survey, and the Trauma Information Exchange Program. Using the Clinical Classification Software to categorize conditions, high transfer rate conditions were placed into nine clinical groups. The authors created a new measure, the "transfer instability index," which estimates the effective number of "transfer partners" for each sending ED: this is designed to measure the stability of outgoing transfer relationships, where higher values of the index indicate less stable relationships. The index provides a measure of how many hospitals a transferring hospital sends its patients to (weighted by how often each transfer partner is used). Regression was used to analyze factors associated with higher values of the index. Sending hospitals had a median of 3.5 effective transfer partners across all conditions. The calculated transfer instability indices varied from 1 to 2.4 across disease categories. In general, higher index values were associated with treating a higher proportion of publicly insured patients: 10 and 12% increases in the Medicare and Medicaid share of ED encounters, respectively, were associated with 10 and 14% increases in the effective number of transfer partners. This public insurance effect held while studying all conditions together as well as within individual disease categories, such as cardiac, neurologic, and

  5. Occupationally-Transferable Skills and Characteristics: Review of Literature and Research. Information Series No. 105.

    ERIC Educational Resources Information Center

    Sjogren, Douglas

    In this synthesis of research and literature on the nature of occupationally-transferable skills, the author identifies skills that seem to be highly transferable in the sense of being general to a number of occupations. He then speculates about characteristics of skills that are generalizable or transferable and discusses some implications for…

  6. Estimating the Information Extracted by a Single Spiking Neuron from a Continuous Input Time Series.

    PubMed

    Zeldenrust, Fleur; de Knecht, Sicco; Wadman, Wytse J; Denève, Sophie; Gutkin, Boris

    2017-01-01

    Understanding the relation between (sensory) stimuli and the activity of neurons (i.e., "the neural code") lies at heart of understanding the computational properties of the brain. However, quantifying the information between a stimulus and a spike train has proven to be challenging. We propose a new ( in vitro ) method to measure how much information a single neuron transfers from the input it receives to its output spike train. The input is generated by an artificial neural network that responds to a randomly appearing and disappearing "sensory stimulus": the hidden state. The sum of this network activity is injected as current input into the neuron under investigation. The mutual information between the hidden state on the one hand and spike trains of the artificial network or the recorded spike train on the other hand can easily be estimated due to the binary shape of the hidden state. The characteristics of the input current, such as the time constant as a result of the (dis)appearance rate of the hidden state or the amplitude of the input current (the firing frequency of the neurons in the artificial network), can independently be varied. As an example, we apply this method to pyramidal neurons in the CA1 of mouse hippocampi and compare the recorded spike trains to the optimal response of the "Bayesian neuron" (BN). We conclude that like in the BN, information transfer in hippocampal pyramidal cells is non-linear and amplifying: the information loss between the artificial input and the output spike train is high if the input to the neuron (the firing of the artificial network) is not very informative about the hidden state. If the input to the neuron does contain a lot of information about the hidden state, the information loss is low. Moreover, neurons increase their firing rates in case the (dis)appearance rate is high, so that the (relative) amount of transferred information stays constant.

  7. Polarization transfer NMR imaging

    DOEpatents

    Sillerud, Laurel O.; van Hulsteyn, David B.

    1990-01-01

    A nuclear magnetic resonance (NMR) image is obtained with spatial information modulated by chemical information. The modulation is obtained through polarization transfer from a first element representing the desired chemical, or functional, information, which is covalently bonded and spin-spin coupled with a second element effective to provide the imaging data. First and second rf pulses are provided at first and second frequencies for exciting the imaging and functional elements, with imaging gradients applied therebetween to spatially separate the nuclei response for imaging. The second rf pulse is applied at a time after the first pulse which is the inverse of the spin coupling constant to select the transfer element nuclei which are spin coupled to the functional element nuclei for imaging. In a particular application, compounds such as glucose, lactate, or lactose, can be labeled with .sup.13 C and metabolic processes involving the compounds can be imaged with the sensitivity of .sup.1 H and the selectivity of .sup.13 C.

  8. Assessing the California Transfer Function: The Transfer Rate and Its Measurement. Conclusions of the Data Needs Task Force.

    ERIC Educational Resources Information Center

    Intersegmental Coordinating Council, Sacramento, CA.

    In the fall of 1989, the Intersegmental Coordinating Council organized the Data Needs Task Force (DNTF) to determine the feasibility of establishing a transfer rate definition. Specifically, the DNTF was charged with defining the information needed to strengthen intersegmental transfer programs, establishing common definitions (including…

  9. 77 FR 50243 - Electronic Fund Transfers (Regulation E)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-20

    ... transfers. DATES: This rule is effective February 7, 2013. FOR FURTHER INFORMATION CONTACT: Eric Goldberg... variation in the demand for remittance transfers, the Bureau believes that an annual figure is the most...

  10. Building a Testate Amoebae-Based Transfer Function in Mountain Fens for Paleohydrological Reconstruction Expansion

    NASA Astrophysics Data System (ADS)

    Lemos, A. L.; Von Ness, K.; Loisel, J.; Karran, D. J.

    2017-12-01

    Minerotrophic peatlands are widespread ecosystems that could be used more often as paleoecological and paleoclimatic archives. However, they have received much less attention than ombrotrophic peat bogs, resulting in very limited information pertaining to their microbial communities. In spite of this, a few studies from Europe have suggested that testate amoebae assemblages from fens could be used as proxies for soil moisture. Here we contribute to this effort by providing a new study from a mountain fen (beaver meadow) located in the Sibbald Research Wetlands in the Rocky Mountains of Kananaskis Provincial Park, Alberta, Canada. Our goals are to (1) quantify the relationships between testate amoebae communities, environmental parameters (pH, water table depth, soil moisture, conductivity, trace elements), and vegetation, (2) identify the key controls on testate amoebae distribution, and (3) develop a transfer function to be used in mountain fens of the region and potentially beyond, given the cosmopolitan nature of testate amoebae taxa. Fifty surface samples were extracted along a wide hydrological gradient in the beaver meadow during Summer 2017, including a current beaver meadow, an abandoned beaver meadow, and a site without apparent beaver activity. These sites were chosen with the hypothesis that distinct testate assemblages might colonize these different types of sites, which would be useful to reconstruct beaver activity downcore. The surface samples from these sites will be the main focus for the new transfer function and provide additional information about climate reconstruction from minerotrophic peatlands such as the mountain fen being studied here. Overall, the building of a testate amoebae-based transfer function in mountain fens is needed in order to expand and improve the use of paleohydrological reconstruction in locations of higher latitude, which are still sparse.

  11. Transfer Learning for Activity Recognition: A Survey

    PubMed Central

    Cook, Diane; Feuz, Kyle D.; Krishnan, Narayanan C.

    2013-01-01

    Many intelligent systems that focus on the needs of a human require information about the activities being performed by the human. At the core of this capability is activity recognition, which is a challenging and well-researched problem. Activity recognition algorithms require substantial amounts of labeled training data yet need to perform well under very diverse circumstances. As a result, researchers have been designing methods to identify and utilize subtle connections between activity recognition datasets, or to perform transfer-based activity recognition. In this paper we survey the literature to highlight recent advances in transfer learning for activity recognition. We characterize existing approaches to transfer-based activity recognition by sensor modality, by differences between source and target environments, by data availability, and by type of information that is transferred. Finally, we present some grand challenges for the community to consider as this field is further developed. PMID:24039326

  12. Improving NASA's technology transfer process through increased screening and evaluation in the information dissemination program

    NASA Technical Reports Server (NTRS)

    Laepple, H.

    1979-01-01

    The current status of NASA's technology transfer system can be improved if the technology transfer process is better understood. This understanding will only be gained if a detailed knowledge about factors generally influencing technology transfer is developed, and particularly those factors affecting technology transfer from government R and D agencies to industry. Secondary utilization of aerospace technology is made more difficult because it depends on a transfer process which crosses established organizational lines of authority and which is outside well understood patterns of technical applications. In the absence of a sound theory about technology transfer and because of the limited capability of government agencies to explore industry's needs, a team approach to screening and evaluation of NASA generated technologies is proposed which calls for NASA, and other organizations of the private and public sectors which influence the transfer of NASA generated technology, to participate in a screening and evaluation process to determine the commercial feasibility of a wide range of technical applications.

  13. Pointwise mutual information quantifies intratumor heterogeneity in tissue sections labeled with multiple fluorescent biomarkers

    PubMed Central

    Spagnolo, Daniel M.; Gyanchandani, Rekha; Al-Kofahi, Yousef; Stern, Andrew M.; Lezon, Timothy R.; Gough, Albert; Meyer, Dan E.; Ginty, Fiona; Sarachan, Brion; Fine, Jeffrey; Lee, Adrian V.; Taylor, D. Lansing; Chennubhotla, S. Chakra

    2016-01-01

    Background: Measures of spatial intratumor heterogeneity are potentially important diagnostic biomarkers for cancer progression, proliferation, and response to therapy. Spatial relationships among cells including cancer and stromal cells in the tumor microenvironment (TME) are key contributors to heterogeneity. Methods: We demonstrate how to quantify spatial heterogeneity from immunofluorescence pathology samples, using a set of 3 basic breast cancer biomarkers as a test case. We learn a set of dominant biomarker intensity patterns and map the spatial distribution of the biomarker patterns with a network. We then describe the pairwise association statistics for each pattern within the network using pointwise mutual information (PMI) and visually represent heterogeneity with a two-dimensional map. Results: We found a salient set of 8 biomarker patterns to describe cellular phenotypes from a tissue microarray cohort containing 4 different breast cancer subtypes. After computing PMI for each pair of biomarker patterns in each patient and tumor replicate, we visualize the interactions that contribute to the resulting association statistics. Then, we demonstrate the potential for using PMI as a diagnostic biomarker, by comparing PMI maps and heterogeneity scores from patients across the 4 different cancer subtypes. Estrogen receptor positive invasive lobular carcinoma patient, AL13-6, exhibited the highest heterogeneity score among those tested, while estrogen receptor negative invasive ductal carcinoma patient, AL13-14, exhibited the lowest heterogeneity score. Conclusions: This paper presents an approach for describing intratumor heterogeneity, in a quantitative fashion (via PMI), which departs from the purely qualitative approaches currently used in the clinic. PMI is generalizable to highly multiplexed/hyperplexed immunofluorescence images, as well as spatial data from complementary in situ methods including FISSEQ and CyTOF, sampling many different components

  14. Pointwise mutual information quantifies intratumor heterogeneity in tissue sections labeled with multiple fluorescent biomarkers.

    PubMed

    Spagnolo, Daniel M; Gyanchandani, Rekha; Al-Kofahi, Yousef; Stern, Andrew M; Lezon, Timothy R; Gough, Albert; Meyer, Dan E; Ginty, Fiona; Sarachan, Brion; Fine, Jeffrey; Lee, Adrian V; Taylor, D Lansing; Chennubhotla, S Chakra

    2016-01-01

    Measures of spatial intratumor heterogeneity are potentially important diagnostic biomarkers for cancer progression, proliferation, and response to therapy. Spatial relationships among cells including cancer and stromal cells in the tumor microenvironment (TME) are key contributors to heterogeneity. We demonstrate how to quantify spatial heterogeneity from immunofluorescence pathology samples, using a set of 3 basic breast cancer biomarkers as a test case. We learn a set of dominant biomarker intensity patterns and map the spatial distribution of the biomarker patterns with a network. We then describe the pairwise association statistics for each pattern within the network using pointwise mutual information (PMI) and visually represent heterogeneity with a two-dimensional map. We found a salient set of 8 biomarker patterns to describe cellular phenotypes from a tissue microarray cohort containing 4 different breast cancer subtypes. After computing PMI for each pair of biomarker patterns in each patient and tumor replicate, we visualize the interactions that contribute to the resulting association statistics. Then, we demonstrate the potential for using PMI as a diagnostic biomarker, by comparing PMI maps and heterogeneity scores from patients across the 4 different cancer subtypes. Estrogen receptor positive invasive lobular carcinoma patient, AL13-6, exhibited the highest heterogeneity score among those tested, while estrogen receptor negative invasive ductal carcinoma patient, AL13-14, exhibited the lowest heterogeneity score. This paper presents an approach for describing intratumor heterogeneity, in a quantitative fashion (via PMI), which departs from the purely qualitative approaches currently used in the clinic. PMI is generalizable to highly multiplexed/hyperplexed immunofluorescence images, as well as spatial data from complementary in situ methods including FISSEQ and CyTOF, sampling many different components within the TME. We hypothesize that PMI will

  15. Telematics and satellites. Part 1: Information systems

    NASA Astrophysics Data System (ADS)

    Burke, W. R.

    1980-06-01

    Telematic systems are identified and described. The applications are examined emphasizing the role played by satellite links. The discussion includes file transfer, examples of distributed processor systems, terminal communication, information retrieval systems, office information systems, electronic preparation and publishing of information, electronic systems for transfer of funds, electronic mail systems, record file transfer characteristics, intra-enterprise networks, and inter-enterprise networks.

  16. Computing algebraic transfer entropy and coupling directions via transcripts

    NASA Astrophysics Data System (ADS)

    Amigó, José M.; Monetti, Roberto; Graff, Beata; Graff, Grzegorz

    2016-11-01

    Most random processes studied in nonlinear time series analysis take values on sets endowed with a group structure, e.g., the real and rational numbers, and the integers. This fact allows to associate with each pair of group elements a third element, called their transcript, which is defined as the product of the second element in the pair times the first one. The transfer entropy of two such processes is called algebraic transfer entropy. It measures the information transferred between two coupled processes whose values belong to a group. In this paper, we show that, subject to one constraint, the algebraic transfer entropy matches the (in general, conditional) mutual information of certain transcripts with one variable less. This property has interesting practical applications, especially to the analysis of short time series. We also derive weak conditions for the 3-dimensional algebraic transfer entropy to yield the same coupling direction as the corresponding mutual information of transcripts. A related issue concerns the use of mutual information of transcripts to determine coupling directions in cases where the conditions just mentioned are not fulfilled. We checked the latter possibility in the lowest dimensional case with numerical simulations and cardiovascular data, and obtained positive results.

  17. A hypertext-based Internet-assessable database for the MSFC Technology Transfer Office

    NASA Technical Reports Server (NTRS)

    Jackson, Jeff

    1994-01-01

    There exists a continuing need to disseminate technical information and facilities capabilities from NASA field centers in an effort to promote the successful transfer of technologies developed with public funds to the private sector. As technology transfer is a stated NASA mission, there exists a critical need for NASA centers to document technology capabilities and disseminate this information on as wide a basis as possible. Certainly local and regional dissemination is critical, but global dissemination of scientific and engineering facilities and capabilities gives NASA centers the ability to contribute to technology transfer on a much broader scale. Additionally, information should be disseminated in a complete and rapidly available form. To accomplish this information dissemination, the unique capabilities of the Internet are being exploited. The Internet allows widescale information distribution in a rapid fashion to aid in the accomplishment of technology transfer goals established by the NASA/MSFC Technology Transfer Office. Rapid information retrieval coupled with appropriate electronic feedback, allows the scientific and technical capabilities of Marshall Space Flight Center, often unique in the world, to be explored by a large number of potential benefactors of NASA (or NASA-derived) technologies. Electronic feedback, coupled with personal contact with the MSFC Technology Transfer Office personnel, allows rapid responses to technical requests from industry and academic personnel as well as private citizens. The remainder of this report gives a brief overview of the Mosaic software and a discussion of technology transfer office and laboratory facilities data that have been made available on the Internet to promote technology transfer.

  18. Gene Transfer Efficiency in Gonococcal Biofilms: Role of Biofilm Age, Architecture, and Pilin Antigenic Variation.

    PubMed

    Kouzel, Nadzeya; Oldewurtel, Enno R; Maier, Berenike

    2015-07-01

    Extracellular DNA is an important structural component of many bacterial biofilms. It is unknown, however, to which extent external DNA is used to transfer genes by means of transformation. Here, we quantified the acquisition of multidrug resistance and visualized its spread under selective and nonselective conditions in biofilms formed by Neisseria gonorrhoeae. The density and architecture of the biofilms were controlled by microstructuring the substratum for bacterial adhesion. Horizontal transfer of antibiotic resistance genes between cocultured strains, each carrying a single resistance, occurred efficiently in early biofilms. The efficiency of gene transfer was higher in early biofilms than between planktonic cells. It was strongly reduced after 24 h and independent of biofilm density. Pilin antigenic variation caused a high fraction of nonpiliated bacteria but was not responsible for the reduced gene transfer at later stages. When selective pressure was applied to dense biofilms using antibiotics at their MIC, the double-resistant bacteria did not show a significant growth advantage. In loosely connected biofilms, the spreading of double-resistant clones was prominent. We conclude that multidrug resistance readily develops in early gonococcal biofilms through horizontal gene transfer. However, selection and spreading of the multiresistant clones are heavily suppressed in dense biofilms. Biofilms are considered ideal reaction chambers for horizontal gene transfer and development of multidrug resistances. The rate at which genes are exchanged within biofilms is unknown. Here, we quantified the acquisition of double-drug resistance by gene transfer between gonococci with single resistances. At early biofilm stages, the transfer efficiency was higher than for planktonic cells but then decreased with biofilm age. The surface topography affected the architecture of the biofilm. While the efficiency of gene transfer was independent of the architecture, spreading of

  19. NASA/DOD Aerospace Knowledge Diffusion Research Project. Paper 9: Information intermediaries and the transfer of aerospace Scientific and Technical Information (STI): A report from the field

    NASA Technical Reports Server (NTRS)

    Eveland, J. D.; Pinelli, Thomas E.

    1991-01-01

    From the NASA/DOD survey data, there can be no way of inferring what strategy for knowledge transfer is best; indeed, given the fact that the respondents were all presumably well qualified professionals, the data tend to call into serious question the idea that any one model might meet the needs of more than a distinct minority of possible users. The evidence to date appears to reinforce the concept that different information environments take many different shapes, and interact with each other and with formal data transmission sources in many different and equally valuable ways. Any overall strategy for improving the effectiveness and efficiency of scientific and technical information sharing must take this divergence into account, and work toward the creation of systems that reinforce true interactive knowledge utilization rather than simply disseminating data.

  20. Metrics to quantify the importance of mixing state for CCN activity

    DOE PAGES

    Ching, Joseph; Fast, Jerome; West, Matthew; ...

    2017-06-21

    It is commonly assumed that models are more prone to errors in predicted cloud condensation nuclei (CCN) concentrations when the aerosol populations are externally mixed. In this work we investigate this assumption by using the mixing state index ( χ) proposed by Riemer and West (2013) to quantify the degree of external and internal mixing of aerosol populations. We combine this metric with particle-resolved model simulations to quantify error in CCN predictions when mixing state information is neglected, exploring a range of scenarios that cover different conditions of aerosol aging. We show that mixing state information does indeed become unimportantmore » for more internally mixed populations, more precisely for populations with χ larger than 75 %. For more externally mixed populations ( χ below 20 %) the relationship of χ and the error in CCN predictions is not unique and ranges from lower than -40 % to about 150 %, depending on the underlying aerosol population and the environmental supersaturation. We explain the reasons for this behavior with detailed process analyses.« less

  1. Metrics to quantify the importance of mixing state for CCN activity

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ching, Joseph; Fast, Jerome; West, Matthew

    It is commonly assumed that models are more prone to errors in predicted cloud condensation nuclei (CCN) concentrations when the aerosol populations are externally mixed. In this work we investigate this assumption by using the mixing state index ( χ) proposed by Riemer and West (2013) to quantify the degree of external and internal mixing of aerosol populations. We combine this metric with particle-resolved model simulations to quantify error in CCN predictions when mixing state information is neglected, exploring a range of scenarios that cover different conditions of aerosol aging. We show that mixing state information does indeed become unimportantmore » for more internally mixed populations, more precisely for populations with χ larger than 75 %. For more externally mixed populations ( χ below 20 %) the relationship of χ and the error in CCN predictions is not unique and ranges from lower than -40 % to about 150 %, depending on the underlying aerosol population and the environmental supersaturation. We explain the reasons for this behavior with detailed process analyses.« less

  2. Information management, today and tomorrow. [acquisition, manipulation, transfer, and display of information

    NASA Technical Reports Server (NTRS)

    Pryor, H. E.

    1975-01-01

    Current problems and future trends in information management are briefly summarized in relation to scientific and technical information management systems and management of management information (planning, marketing, and operations).

  3. Assessing segment- and corridor-based travel-time reliability on urban freeways tech transfer summary : tech transfer summary.

    DOT National Transportation Integrated Search

    2016-09-01

    Travel time and travel-time reliability have been used as performance : measures to evaluate traffic system conditions and develop advanced : traveler information and traffic management systems. The objectives of this research were to: : - Quantify s...

  4. Energy Transfer in Turbulence under Rotation

    NASA Astrophysics Data System (ADS)

    Aluie, Hussein; Buzzicotti, Michele; Biferale, Luca; Linkmann, Moritz

    2017-11-01

    It is known that rapidly rotating turbulent flows are characterized by the emergence of simultaneous direct and inverse energy cascades. However, the organization of interactions which leads to this complex dynamics remains unclear. Two different mechanisms are known to be able to transfer energy upscale in a turbulent flow: (i) 2-dimensional interactions amongst triads lying on the 2D3C (or slow) manifold, and (ii) purely 3-dimensional interactions between a sub-set of triads with the same sign of helicity (homo-chiral). Here, we perform a numerical study of high Reynolds rotating flows by means of direct numerical simulations (DNS), in different parameter regimes to highlight both forward and inverse cascade regimes. We find that the inverse cascade at wavenumbers close to the forcing scale is generated by the dominance of homo-chiral interactions which couple the 3-dimensional bulk and the 2D3C plane. This coupling produces an accumulation of energy in the 2D3C plane, which then transfers energy to smaller wavenumbers thanks to a 2-dimensional mechanism. We further analyze the energy transfer that occurs in different regions in the real-space domain. In particular we distinguish high strain from high vorticity regions and quantify their contributions to the cascade.

  5. Waste Transfer Stations: Involved Citizens Make the Difference

    EPA Pesticide Factsheets

    Provides key information involved citizens will need to develop an opinion about a proposed or modified transfer station. Also provides ideas on how to get involved to enhance the value of the waste transfer station.

  6. Using Carbon Nanotubes for Nanometer-Scale Energy Transfer Microscopy

    NASA Astrophysics Data System (ADS)

    Johnston, Jessica; Shafran, Eyal; Mangum, Ben; Mu, Chun; Gerton, Jordan

    2009-10-01

    We investigate optical energy transfer between fluorophores and carbon nanotubes (CNTs). CNTs are grown on Si-oxide wafers by chemical vapor deposition (CVD), lifted off substrates by atomic force microscope (AFM) tips via Van der Waals forces, then shortened by electrical pulses. The tip-attached CNTs are scanned over fluorescent CdSe-ZnS quantum dots (QDs) with sub-nm precision while recording the fluorescence rate. A novel photon counting technique enables us to produce 3D maps of the QD-CNT coupling, revealing nanoscale lateral and vertical features. All CNTs tested (>50) strongly quenched the QD fluorescence, apparently independent of chirality. In some data, a delay in the recovery of QD fluorescence following CNT-QD contact was observed, suggesting possible charge transfer in this system. In the future, we will perform time-resolved studies to quantify the rate of energy and charge transfer processes and study the possible differences in fluorescence quenching and nanotube-QD energy transfer when comparing single-walled (SW) versus multi-walled (MW) CNTs, attempting to grow substrates consisting primarily of SW or MWCNTs and characterizing the structure of tip-attached CNTs using optical spectroscopy.

  7. Space benefits: The secondary application of aerospace technology in other sectors of the economy. [(information dissemination and technology transfer from NASA programs)

    NASA Technical Reports Server (NTRS)

    1974-01-01

    Space Benefits is a publication that has been prepared for the NASA Technology Utilization Office by the Denver Research Institute's Program for Transfer Research and Impact Studies, to provide the Agency with accurate, convenient, and integrated resource information on the transfer of aerospace technology to other sectors of the U.S. economy. The technological innovations derived from NASA space programs and their current applications in the following areas are considered: (1) manufacturing consumer products, (2) manufacturing capital goods, (3) new consumer products and retailing, (4) electric utilities, (5) environmental quality, (6) food production and processing, (7) government, (8) petroleum and gas, (9) construction, (10) law enforcement, and (11) highway transportation.

  8. Equitability, mutual information, and the maximal information coefficient.

    PubMed

    Kinney, Justin B; Atwal, Gurinder S

    2014-03-04

    How should one quantify the strength of association between two random variables without bias for relationships of a specific form? Despite its conceptual simplicity, this notion of statistical "equitability" has yet to receive a definitive mathematical formalization. Here we argue that equitability is properly formalized by a self-consistency condition closely related to Data Processing Inequality. Mutual information, a fundamental quantity in information theory, is shown to satisfy this equitability criterion. These findings are at odds with the recent work of Reshef et al. [Reshef DN, et al. (2011) Science 334(6062):1518-1524], which proposed an alternative definition of equitability and introduced a new statistic, the "maximal information coefficient" (MIC), said to satisfy equitability in contradistinction to mutual information. These conclusions, however, were supported only with limited simulation evidence, not with mathematical arguments. Upon revisiting these claims, we prove that the mathematical definition of equitability proposed by Reshef et al. cannot be satisfied by any (nontrivial) dependence measure. We also identify artifacts in the reported simulation evidence. When these artifacts are removed, estimates of mutual information are found to be more equitable than estimates of MIC. Mutual information is also observed to have consistently higher statistical power than MIC. We conclude that estimating mutual information provides a natural (and often practical) way to equitably quantify statistical associations in large datasets.

  9. Energy Efficiency Maximization for WSNs with Simultaneous Wireless Information and Power Transfer

    PubMed Central

    Yu, Hongyan; Zhang, Yongqiang; Yang, Yuanyuan; Ji, Luyue

    2017-01-01

    Recently, the simultaneous wireless information and power transfer (SWIPT) technique has been regarded as a promising approach to enhance performance of wireless sensor networks with limited energy supply. However, from a green communication perspective, energy efficiency optimization for SWIPT system design has not been investigated in Wireless Rechargeable Sensor Networks (WRSNs). In this paper, we consider the tradeoffs between energy efficiency and three factors including spectral efficiency, the transmit power and outage target rate for two different modes, i.e., power splitting (PS) and time switching modes (TS), at the receiver. Moreover, we formulate the energy efficiency maximization problem subject to the constraints of minimum Quality of Service (QoS), minimum harvested energy and maximum transmission power as non-convex optimization problem. In particular, we focus on optimizing power control and power allocation policy in PS and TS modes to maximize energy efficiency of data transmission. For PS and TS modes, we propose the corresponding algorithm to characterize a non-convex optimization problem that takes into account the circuit power consumption and the harvested energy. By exploiting nonlinear fractional programming and Lagrangian dual decomposition, we propose suboptimal iterative algorithms to obtain the solutions of non-convex optimization problems. Furthermore, we derive the outage probability and effective throughput from the scenarios that the transmitter does not or partially know the channel state information (CSI) of the receiver. Simulation results illustrate that the proposed optimal iterative algorithm can achieve optimal solutions within a small number of iterations and various tradeoffs between energy efficiency and spectral efficiency, transmit power and outage target rate, respectively. PMID:28820496

  10. Energy Efficiency Maximization for WSNs with Simultaneous Wireless Information and Power Transfer.

    PubMed

    Yu, Hongyan; Zhang, Yongqiang; Guo, Songtao; Yang, Yuanyuan; Ji, Luyue

    2017-08-18

    Recently, the simultaneous wireless information and power transfer (SWIPT) technique has been regarded as a promising approach to enhance performance of wireless sensor networks with limited energy supply. However, from a green communication perspective, energy efficiency optimization for SWIPT system design has not been investigated in Wireless Rechargeable Sensor Networks (WRSNs). In this paper, we consider the tradeoffs between energy efficiency and three factors including spectral efficiency, the transmit power and outage target rate for two different modes, i.e., power splitting (PS) and time switching modes (TS), at the receiver. Moreover, we formulate the energy efficiency maximization problem subject to the constraints of minimum Quality of Service (QoS), minimum harvested energy and maximum transmission power as non-convex optimization problem. In particular, we focus on optimizing power control and power allocation policy in PS and TS modes to maximize energy efficiency of data transmission. For PS and TS modes, we propose the corresponding algorithm to characterize a non-convex optimization problem that takes into account the circuit power consumption and the harvested energy. By exploiting nonlinear fractional programming and Lagrangian dual decomposition, we propose suboptimal iterative algorithms to obtain the solutions of non-convex optimization problems. Furthermore, we derive the outage probability and effective throughput from the scenarios that the transmitter does not or partially know the channel state information (CSI) of the receiver. Simulation results illustrate that the proposed optimal iterative algorithm can achieve optimal solutions within a small number of iterations and various tradeoffs between energy efficiency and spectral efficiency, transmit power and outage target rate, respectively.

  11. Matching tutors and students: effective strategies for information transfer between circuits

    NASA Astrophysics Data System (ADS)

    Tesileanu, Tiberiu; Balasubramanian, Vijay; Olveczky, Bence

    Many neural circuits transfer learned information to downstream circuits: hippocampal-dependent memories are consolidated into long-term memories elsewhere; motor cortex is essential for skill learning but dispensable for execution; anterior forebrain pathway (AFP) in songbirds drives short-term improvements in song that are later consolidated in pre-motor area RA. We show how to match instructive signals from tutor circuits to synaptic plasticity rules in student circuits to achieve effective two-stage learning. We focus on learning sequential patterns where a timebase is transformed into motor commands by connectivity with a `student' area. If the sign of the synaptic change is given by the magnitude of tutor input, a good teaching strategy uses a strong (weak) tutor signal if student output is below (above) its target. If instead timing of tutor input relative to the timebase determines the sign of synaptic modifications, a good instructive signal accumulates the errors in student output as the motor program progresses. We demonstrate song learning in a biologically-plausible model of the songbird circuit given diverse plasticity rules interpolating between those described above. The model also reproduces qualitative firing statistics of RA neurons in juveniles and adults. Also affiliated to CUNY - Graduate Center.

  12. Radiation exposure and performance of multiple burn LEO-GEO orbit transfer trajectories

    NASA Technical Reports Server (NTRS)

    Gorland, S. H.

    1985-01-01

    Many potential strategies exist for the transfer of spacecraft from low Earth orbit (LEO) to geosynchronous (GEO) orbit. One strategy has generally been utilized, that being a single impulsive burn at perigee and a GEO insertion burn at apogee. Multiple burn strategies were discussed for orbit transfer vehicles (OTVs) but the transfer times and radiation exposure, particularly for potentially manned missions, were used as arguments against those options. Quantitative results concerning the trip time and radiation encountered by multiple burn orbit transfer missions in order to establish the feasibility of manned missions, the vulnerability of electronics, and the shielding requirements are presented. The performance of these multiple burn missions is quantified in terms of the payload and propellant variances from the minimum energy mission transfer. The missions analyzed varied from one to eight perigee burns and ranged from a high thrust, 1 g acceleration, cryogenic hydrogen-oxygen chemical prpulsion system to a continuous burn, 0.001 g acceleration, hydrogen fueled resistojet propulsion system with a trip time of 60 days.

  13. Attrition and performance of community college transfers

    PubMed Central

    Aulck, Lovenoor; West, Jevin

    2017-01-01

    Community colleges are an important part of the US higher education landscape, yet the aptitude and preparedness of student transfers to baccalaureate institutions is often called into question. Examining transcript records and demographic information of nearly 70,000 students across over 15 years of registrar records at a public university, this study performed a descriptive analysis of the persistence, performance, and academic migration patterns of community college transfers, transfers from four-year institutions, and freshmen entrants. We found little difference between community college transfers and freshmen entrants in terms of post-transfer grades and persistence. Transfers from four-year institutions had higher grades but also had higher attrition rates than their peers. This study also found no strong evidence of transfer shock on students’ post-transfer grades. When examining the tendencies of students to shift fields of study during their educational pursuits, the academic migration patterns of transfer students were more concentrated than those of freshmen entrants. PMID:28407002

  14. Effects of bilateral swing-away grab bars on the biomechanics of stand-to-sit and sit-to-stand toilet transfers.

    PubMed

    Lee, Su Jin; Mehta-Desai, Ricky; Oh, Kyunggeune; Sanford, Jon; Prilutsky, Boris I

    2018-03-09

    Kinetic characteristics of transfers to and from a toilet performed using bilateral grab bars are not fully quantified to inform grab bar design and configuration. The purpose of this study was to (1) determine effects of bilateral swing-away grab bars on peaks of ankle, knee and hip joint moments during grab bar assisted stand-to-sit and sit-to-stand transfers; and (2) determine effects of three different heights and widths of swing-away grab bars on the same kinetic characteristics. Healthy subjects (N = 11, age 25-58 years) performed stand-to-sit and sit-to-stand transfers with and without grab bars. In transfers with grab bars, 9 grab bar configurations were tested by varying their height from the floor (0.787 m, 0.813 m, 0.838 m; 31″-33″) and width, the distance of each grab bar from the toilet's centerline (0.330 m, 0.356 m, 0.381 m; 13″-15″). Motion capture, force plate and inverse dynamics analysis were used to determine lower limb joint moments. The use of bilateral grab bars generally reduced the peak magnitude of extension moments at lower limb joints during stand-to-sit and sit-to-stand transfers (p < .05), except the ankle joint moments during stand-to-sit transfers. Relatively few differences in peak joint moments were found between studied grab bar widths or heights. The obtained results suggest that the studied ranges of grab bar configurations reduce moment demands on the leg joints and thus decrease difficulty and required lower limb muscle effort to perform the transfers. Implications for Rehabilitation Maximizing the benefits of assistive technology in the built environment requires a careful assessment of their spatial and configurational dimensions, especially in respect to the needs and abilities of the intended users. Examining the kinetic characteristics of transfers to and from a toilet using the swing-away grab bars is useful for informing grab bar design and configuration recommendations for assisted living

  15. A novel methodology to characterize interfacility transfer strategies in a trauma transfer network.

    PubMed

    Gomez, David; Haas, Barbara; Larsen, Kristian; Alali, Aziz S; MacDonald, Russell D; Singh, Jeffrey M; Tien, Homer; Iwashyna, Theodore J; Rubenfeld, Gordon; Nathens, Avery B

    2016-10-01

    More than half of severely injured patients are initially transported from the scene of injury to nontrauma centers (NTCs), with many requiring subsequent transfer to trauma center (TC) care. Definitive care in the setting of severe injury is time sensitive. However, transferring severely injured patients from an NTC is a complex process often fraught with delays. Selection of the receiving TC and the mode of interfacility transport both strongly influence total transfer time and are highly amenable to quality improvement initiatives. We analyzed transfer strategies, defined as the pairing of a destination and mode of transport (land vs. rotary wing vs. fixed wing), for severely injured adult patients. Existing transfer strategies at each NTC were derived from trauma registry data. Geographic Information Systems network analysis was used to identify the strategy that minimized transfer times the most as well as alternate strategies (+15 or +30 minutes) for each NTC. Transfer network efficiency was characterized based on optimality and stability. We identified 7,702 severely injured adult patients transferred from 146 NTCs to 9 TCs. Nontrauma centers transferred severely injured patients to a median of 3 (interquartile range, 1-4) different TCs and utilized a median of 4 (interquartile range, 2-6) different transfer strategies. After allowing for the use of alternate transfer strategies, 73.1% of severely injured patients were transported using optimal/alternate strategies, and only 40.4% of NTCs transferred more than 90% of patients using an optimal/alternate transfer strategy. Three quarters (75.5%) of transfers occurred between NTCs and their most common receiving TC. More than a quarter of patients with severe traumatic injuries undergoing interfacility transport to a TC in Ontario are consistently transported using a nonoptimal combination of destination and mode of transport. Our novel analytic approach can be easily adapted to different system configurations

  16. Granger Causality and Transfer Entropy Are Equivalent for Gaussian Variables

    NASA Astrophysics Data System (ADS)

    Barnett, Lionel; Barrett, Adam B.; Seth, Anil K.

    2009-12-01

    Granger causality is a statistical notion of causal influence based on prediction via vector autoregression. Developed originally in the field of econometrics, it has since found application in a broader arena, particularly in neuroscience. More recently transfer entropy, an information-theoretic measure of time-directed information transfer between jointly dependent processes, has gained traction in a similarly wide field. While it has been recognized that the two concepts must be related, the exact relationship has until now not been formally described. Here we show that for Gaussian variables, Granger causality and transfer entropy are entirely equivalent, thus bridging autoregressive and information-theoretic approaches to data-driven causal inference.

  17. The role of intra-NAPL diffusion on mass transfer from MGP residuals

    NASA Astrophysics Data System (ADS)

    Shafieiyoun, Saeid; Thomson, Neil R.

    2018-06-01

    An experimental and computational study was performed to investigate the role of multi-component intra-NAPL diffusion on NAPL-water mass transfer. Molecular weight and the NAPL component concentrations were determined to be the most important parameters affecting intra-NAPL diffusion coefficients. Four NAPLs with different viscosities but the same quantified mass were simulated. For a spherical NAPL body, a combination of NAPL properties and interphase mass transfer rate can result in internal diffusion limitations. When the main intra-NAPL diffusion coefficients are in the range of self-diffusion coefficients (10-5 to 10-6 cm2/s), dissolution is not limited by internal diffusion except for high mass transfer rate coefficients (>180 cm/day). For a complex and relatively high viscous NAPL (>50 g/(cm s)), smaller intra-NAPL diffusion coefficients (<10-8) are expected and even low mass transfer rate coefficients ( 6 cm/day) can result in diffusion-limited dissolution.

  18. Towards rationally redesigning bacterial signaling systems using information encoded in abundant sequence data

    NASA Astrophysics Data System (ADS)

    Cheng, Ryan; Morcos, Faruck; Levine, Herbert; Onuchic, Jose

    2014-03-01

    An important challenge in biology is to distinguish the subset of residues that allow bacterial two-component signaling (TCS) proteins to preferentially interact with their correct TCS partner such that they can bind and transfer signal. Detailed knowledge of this information would allow one to search sequence-space for mutations that can systematically tune the signal transmission between TCS partners as well as re-encode a TCS protein to preferentially transfer signals to a non-partner. Motivated by the notion that this detailed information is found in sequence data, we explore the mutual sequence co-evolution between signaling partners to infer how mutations can positively or negatively alter their interaction. Using Direct Coupling Analysis (DCA) for determining evolutionarily conserved interprotein interactions, we apply a DCA-based metric to quantify mutational changes in the interaction between TCS proteins and demonstrate that it accurately correlates with experimental mutagenesis studies probing the mutational change in the in vitro phosphotransfer. Our methodology serves as a potential framework for the rational design of TCS systems as well as a framework for the system-level study of protein-protein interactions in sequence-rich systems. This research has been supported by the NSF INSPIRE award MCB-1241332 and by the CTBP sponsored by the NSF (Grant PHY-1308264).

  19. Quantifying CO2 Emissions From Individual Power Plants From Space

    NASA Astrophysics Data System (ADS)

    Nassar, Ray; Hill, Timothy G.; McLinden, Chris A.; Wunch, Debra; Jones, Dylan B. A.; Crisp, David

    2017-10-01

    In order to better manage anthropogenic CO2 emissions, improved methods of quantifying emissions are needed at all spatial scales from the national level down to the facility level. Although the Orbiting Carbon Observatory 2 (OCO-2) satellite was not designed for monitoring power plant emissions, we show that in some cases, CO2 observations from OCO-2 can be used to quantify daily CO2 emissions from individual middle- to large-sized coal power plants by fitting the data to plume model simulations. Emission estimates for U.S. power plants are within 1-17% of reported daily emission values, enabling application of the approach to international sites that lack detailed emission information. This affirms that a constellation of future CO2 imaging satellites, optimized for point sources, could monitor emissions from individual power plants to support the implementation of climate policies.

  20. Improving the Transition of Care in Patients Transferred Through the Ochsner Medical Center Transfer Center

    PubMed Central

    Amedee, Ronald G.; Maronge, Genevieve F.; Pinsky, William W.

    2012-01-01

    Background Patient transfers from other hospitals within the Ochsner Health System to the main campus are coordinated through a Transfer Center that was established in fall 2008. We analyzed the transfer process to assess distinct opportunities to enhance the overall transition of patient care. Methods We surveyed internal medicine residents and nocturnists to determine their satisfaction with transfers in terms of safety, efficiency, and usefulness of information provided at the time of transfer. After a kaizen event at which complementary goals for the institution and members of the study team were recognized and implemented, we resurveyed the group to evaluate improvement in the transfer process. Results The preintervention average satisfaction score was 1.18 (SD=0.46), while the postintervention score was 3.7 (SD=1.01). A t test showed a significant difference in the average scores between the preintervention and postintervention surveys (P<0.0001). Conclusions By including residents in the transfer calls (a result of the kaizen event), data were collected that facilitated fewer and higher quality handoffs that were performed in less time. In addition, the process resulted in increased awareness of the value of resident participation in institutional quality improvement projects. PMID:23267257

  1. Improving the transition of care in patients transferred through the ochsner medical center transfer center.

    PubMed

    Amedee, Ronald G; Maronge, Genevieve F; Pinsky, William W

    2012-01-01

    Patient transfers from other hospitals within the Ochsner Health System to the main campus are coordinated through a Transfer Center that was established in fall 2008. We analyzed the transfer process to assess distinct opportunities to enhance the overall transition of patient care. We surveyed internal medicine residents and nocturnists to determine their satisfaction with transfers in terms of safety, efficiency, and usefulness of information provided at the time of transfer. After a kaizen event at which complementary goals for the institution and members of the study team were recognized and implemented, we resurveyed the group to evaluate improvement in the transfer process. The preintervention average satisfaction score was 1.18 (SD=0.46), while the postintervention score was 3.7 (SD=1.01). A t test showed a significant difference in the average scores between the preintervention and postintervention surveys (P<0.0001). By including residents in the transfer calls (a result of the kaizen event), data were collected that facilitated fewer and higher quality handoffs that were performed in less time. In addition, the process resulted in increased awareness of the value of resident participation in institutional quality improvement projects.

  2. Environmental and socio-economic change in Thailand: quantifying spatio-temporal risk factors of dengue to inform decision making

    NASA Astrophysics Data System (ADS)

    Rodo, X.; Lowe, R.; Karczewska-Gibert, A.; Cazelles, B.

    2013-12-01

    -temporal probabilistic predictions of dengue. Potential risk factors considered include altitude, land cover, proximity to road/rail networks and water bodies, temperature and precipitation, oceanic indicators, intervention activities, air traffic volume, population movement, urbanisation and sanitation indicators. In order to quantify unknown or unmeasured dengue risk factors, we use spatio-temporal random effects in the model framework. This helps identify those available indicators which could significantly contribute to a dengue early warning system. We use this model to quantify the extent to which climate indicators can explain variations in dengue risk. This allows us to assess the potential utility of forecast climate information in a dengue decision support system for Thailand. Taking advantage of lead times of several months provided by climate forecasts, public health officials may be able to more efficiently allocate intervention measures, such as targeted vector control activities and provision of medication to deal with more deadly forms of the disease, well ahead of an imminent dengue epidemic.

  3. Experimental determination of the key heat transfer mechanisms in pharmaceutical freeze-drying.

    PubMed

    Ganguly, Arnab; Nail, Steven L; Alexeenko, Alina

    2013-05-01

    The study is aimed at quantifying the relative contribution of key heat transfer modes in lyophilization. Measurements of vial heat transfer rates in a laboratory-scale freeze-dryer were performed using pure water, which was partially sublimed under various conditions. The separation distance between the shelf and the vial was systematically varied, and sublimation rates were determined gravimetrically. The heat transfer rates were observed to be independent of separation distance between the vial and the shelf and linearly dependent on pressure in the free molecular flow limit, realized at low pressures (<50 mTorr). However, under higher pressures (>120 mTorr), heat transfer rates were independent of pressure and inversely proportional to separation distance. Previous heat transfer studies in conventional freeze-drying cycles have attributed a dominant portion of the total heat transfer to radiation, the rest to conduction, whereas convection has been found to be insignificant. Although the measurements reported here confirm the significance of the radiative and gas conduction components, the convective component has been found to be comparable to the gas conduction contribution at pressures greater than 100 mTorr. The current investigation supports the conclusion that the convective component of the heat transfer cannot be ignored in typical laboratory-scale freeze-drying conditions. Copyright © 2013 Wiley Periodicals, Inc.

  4. Quantifying errors without random sampling.

    PubMed

    Phillips, Carl V; LaPole, Luwanna M

    2003-06-12

    All quantifications of mortality, morbidity, and other health measures involve numerous sources of error. The routine quantification of random sampling error makes it easy to forget that other sources of error can and should be quantified. When a quantification does not involve sampling, error is almost never quantified and results are often reported in ways that dramatically overstate their precision. We argue that the precision implicit in typical reporting is problematic and sketch methods for quantifying the various sources of error, building up from simple examples that can be solved analytically to more complex cases. There are straightforward ways to partially quantify the uncertainty surrounding a parameter that is not characterized by random sampling, such as limiting reported significant figures. We present simple methods for doing such quantifications, and for incorporating them into calculations. More complicated methods become necessary when multiple sources of uncertainty must be combined. We demonstrate that Monte Carlo simulation, using available software, can estimate the uncertainty resulting from complicated calculations with many sources of uncertainty. We apply the method to the current estimate of the annual incidence of foodborne illness in the United States. Quantifying uncertainty from systematic errors is practical. Reporting this uncertainty would more honestly represent study results, help show the probability that estimated values fall within some critical range, and facilitate better targeting of further research.

  5. Process-level model evaluation: a snow and heat transfer metric

    NASA Astrophysics Data System (ADS)

    Slater, Andrew G.; Lawrence, David M.; Koven, Charles D.

    2017-04-01

    Land models require evaluation in order to understand results and guide future development. Examining functional relationships between model variables can provide insight into the ability of models to capture fundamental processes and aid in minimizing uncertainties or deficiencies in model forcing. This study quantifies the proficiency of land models to appropriately transfer heat from the soil through a snowpack to the atmosphere during the cooling season (Northern Hemisphere: October-March). Using the basic physics of heat diffusion, we investigate the relationship between seasonal amplitudes of soil versus air temperatures due to insulation from seasonal snow. Observations demonstrate the anticipated exponential relationship of attenuated soil temperature amplitude with increasing snow depth and indicate that the marginal influence of snow insulation diminishes beyond an effective snow depth of about 50 cm. A snow and heat transfer metric (SHTM) is developed to quantify model skill compared to observations. Land models within the CMIP5 experiment vary widely in SHTM scores, and deficiencies can often be traced to model structural weaknesses. The SHTM value for individual models is stable over 150 years of climate, 1850-2005, indicating that the metric is insensitive to climate forcing and can be used to evaluate each model's representation of the insulation process.

  6. Process-level model evaluation: a snow and heat transfer metric

    DOE PAGES

    Slater, Andrew G.; Lawrence, David M.; Koven, Charles D.

    2017-04-20

    Land models require evaluation in order to understand results and guide future development. Examining functional relationships between model variables can provide insight into the ability of models to capture fundamental processes and aid in minimizing uncertainties or deficiencies in model forcing. This study quantifies the proficiency of land models to appropriately transfer heat from the soil through a snowpack to the atmosphere during the cooling season (Northern Hemisphere: October–March). Using the basic physics of heat diffusion, we investigate the relationship between seasonal amplitudes of soil versus air temperatures due to insulation from seasonal snow. Observations demonstrate the anticipated exponential relationshipmore » of attenuated soil temperature amplitude with increasing snow depth and indicate that the marginal influence of snow insulation diminishes beyond an effective snow depth of about 50 cm. A snow and heat transfer metric (SHTM) is developed to quantify model skill compared to observations. Land models within the CMIP5 experiment vary widely in SHTM scores, and deficiencies can often be traced to model structural weaknesses. The SHTM value for individual models is stable over 150 years of climate, 1850–2005, indicating that the metric is insensitive to climate forcing and can be used to evaluate each model's representation of the insulation process.« less

  7. Process-level model evaluation: a snow and heat transfer metric

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Slater, Andrew G.; Lawrence, David M.; Koven, Charles D.

    Land models require evaluation in order to understand results and guide future development. Examining functional relationships between model variables can provide insight into the ability of models to capture fundamental processes and aid in minimizing uncertainties or deficiencies in model forcing. This study quantifies the proficiency of land models to appropriately transfer heat from the soil through a snowpack to the atmosphere during the cooling season (Northern Hemisphere: October–March). Using the basic physics of heat diffusion, we investigate the relationship between seasonal amplitudes of soil versus air temperatures due to insulation from seasonal snow. Observations demonstrate the anticipated exponential relationshipmore » of attenuated soil temperature amplitude with increasing snow depth and indicate that the marginal influence of snow insulation diminishes beyond an effective snow depth of about 50 cm. A snow and heat transfer metric (SHTM) is developed to quantify model skill compared to observations. Land models within the CMIP5 experiment vary widely in SHTM scores, and deficiencies can often be traced to model structural weaknesses. The SHTM value for individual models is stable over 150 years of climate, 1850–2005, indicating that the metric is insensitive to climate forcing and can be used to evaluate each model's representation of the insulation process.« less

  8. USGS Regional Groundwater Availability Studies: Quantifying Aquifer Response

    NASA Astrophysics Data System (ADS)

    Reeves, H. W.

    2017-12-01

    The U.S. Geological Survey (USGS) identified six challenges in determining groundwater availability: 1) limited direct measurement, 2) varying response times for different systems, 3) varying spatial scales for different availability questions and aquifer systems, 4) varying tolerance to changes in water levels or outflows, 5) redistribution of stresses and potential return-flow of water pumped from the system, and 6) varying chemical quality of groundwater and the role of quality in determining suitability for different uses. USGS Regional groundwater availability studies are designed to address these challenges. USGS regional groundwater availability studies focus on quantifying the groundwater budget for principal aquifers and determining how this budget has changed in response to pumping or variations in climate. This focus requires relating limited measurements to a quantitative understanding of the temporal and spatial response of regional aquifers. For most principal aquifer studies, aquifer response is quantified using regional groundwater flow models, and USGS regional groundwater availability studies have provided test cases for the development and application of advanced modeling techniques and methods. Results from regional studies from the Lake Michigan Basin and Northern Atlantic Coastal Plain illustrate how different parts of these systems respond differently to pumping with some areas showing large drawdowns and others having much less drawdown but greater capture of discharge. The Central Valley and Mississippi Embayment studies show how extensive pumping and transfer of water have resulted in much more groundwater moving through the aquifer system under current conditions compared to pre-development. These and other results from regional studies will be explored to illustrate how regional groundwater availability and related studies address the six challenges to determining groundwater availability.

  9. Disregarding Graduated Treatment: Why Transfer Aggravates Recidivism

    ERIC Educational Resources Information Center

    Johnson, Kristin; Lanza-Kaduce, Lonn; Woolard, Jennifer

    2011-01-01

    These data merge correctional histories with official state and courthouse information for a sample of teenage offenders, some of whom had been transferred to the adult system. Previous research indicated that transfer aggravates recidivism after the age of 18. The correctional data allow the examination of the relationship between sanctions and…

  10. 40 CFR 152.135 - Transfer of registration.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., spinoff, bankruptcy transfer (no financial information need be disclosed); (7) A statement that the transferor and transferee understand that any false statement may be punishable under 18 U.S.C. 1001; and (8...) The name(s) and EPA registration number(s) of the product(s) being transferred; (4) A statement that...

  11. Temperature coefficient for modeling denitrification in surface water sediments using the mass transfer coefficient

    Treesearch

    T.W. Appelboom; G.M. Chescheir; F. Birgand; R.W. Skaggs; J.W. Gilliam; D. Amatya

    2010-01-01

    Watershed modeling has become an important tool for researchers. Modeling nitrate transport within drainage networks requires quantifying the denitrification within the sediments in canals and streams. In a previous study, several of the authors developed an equation using a term called a mass transfer coefficient to mathematically describe sediment denitrification....

  12. Temperature coefficient for modeling denitrification in surface water sediments using the mass transfer coefficient.

    Treesearch

    T.W. Appelboom; G.M. Chescheir; F. Birgand; R.W. Skaggs; J.W. Gilliam; D. Amatya

    2010-01-01

    Watershed modeling has become an important tool for researchers. Modeling nitrate transport within drainage networks requires quantifying the denitrification within the sediments in canals and streams. In a previous study, several of the authors developed an equation using a term called a mass transfer coefficient to mathematically describe sediment denitrification....

  13. Using multilevel models to quantify heterogeneity in resource selection

    USGS Publications Warehouse

    Wagner, Tyler; Diefenbach, Duane R.; Christensen, Sonja; Norton, Andrew S.

    2011-01-01

    Models of resource selection are being used increasingly to predict or model the effects of management actions rather than simply quantifying habitat selection. Multilevel, or hierarchical, models are an increasingly popular method to analyze animal resource selection because they impose a relatively weak stochastic constraint to model heterogeneity in habitat use and also account for unequal sample sizes among individuals. However, few studies have used multilevel models to model coefficients as a function of predictors that may influence habitat use at different scales or quantify differences in resource selection among groups. We used an example with white-tailed deer (Odocoileus virginianus) to illustrate how to model resource use as a function of distance to road that varies among deer by road density at the home range scale. We found that deer avoidance of roads decreased as road density increased. Also, we used multilevel models with sika deer (Cervus nippon) and white-tailed deer to examine whether resource selection differed between species. We failed to detect differences in resource use between these two species and showed how information-theoretic and graphical measures can be used to assess how resource use may have differed. Multilevel models can improve our understanding of how resource selection varies among individuals and provides an objective, quantifiable approach to assess differences or changes in resource selection.

  14. Challenges of Remote Sensing and Spatial Information Education and Technology Transfer in a Fast Developing Industry

    NASA Astrophysics Data System (ADS)

    Tsai, F.; Chen, L.-C.

    2014-04-01

    During the past decade, Taiwan has experienced an unusual and fast growing in the industry of mapping, remote sensing, spatial information and related markets. A successful space program and dozens of advanced airborne and ground-based remote sensing instruments as well as mobile mapping systems have been implemented and put into operation to support the vast demands of geospatial data acquisition. Moreover, in addition to the government agencies and research institutes, there are also tens of companies in the private sector providing geo-spatial data and services. However, the fast developing industry is also posing a great challenge to the education sector in Taiwan, especially the higher education for geo-spatial information. Facing this fast developing industry, the demands of skilled professionals and new technologies in order to address diversified needs are indubitably high. Consequently, while delighting in the expanding and prospering benefitted from the fast growing industry, how to fulfill these demands has become a challenge for the remote sensing and spatial information disciplines in the higher education institutes in Taiwan. This paper provides a brief insight into the status of the remote sensing and spatial information industry in Taiwan as well as the challenges of the education and technology transfer to support the increasing demands and to ensure the continuous development of the industry. In addition to the report of the current status of the remote sensing and spatial information related courses and programs in the colleges and universities, current and potential threatening issues and possible resolutions are also discussed in different points of view.

  15. Study of mass and momentum transfer in diesel sprays based on X-ray mass distribution measurements and on a theoretical derivation

    NASA Astrophysics Data System (ADS)

    Desantes, J. M.; Salvador, F. J.; López, J. J.; de La Morena, J.

    2011-02-01

    In this paper, a research aimed at quantifying mass and momentum transfer in the near-nozzle field of diesel sprays injected into stagnant ambient air is reported. The study combines X-ray measurements for two different nozzles and axial positions, which provide mass distributions in the spray, with a theoretical model based on momentum flux conservation, which was previously validated. This investigation has allowed the validation of Gaussian profiles for local fuel concentration and velocity near the nozzle exit, as well as the determination of Schmidt number at realistic diesel spray conditions. This information could be very useful for those who are interested in spray modeling, especially at high-pressure injection conditions.

  16. Cockpit display of hazardous weather information

    NASA Technical Reports Server (NTRS)

    Hansman, R. John, Jr.; Wanke, Craig

    1990-01-01

    Information transfer and display issues associated with the dissemination of hazardous weather warnings are studied in the context of windshear alerts. Operational and developmental windshear detection systems are briefly reviewed. The July 11, 1988 microburst events observed as part of the Denver Terminal Doppler Weather Radar (TDWR) operational evaluation are analyzed in terms of information transfer and the effectiveness of the microburst alerts. Information transfer, message content and display issues associated with microburst alerts generated from ground based sources are evaluated by means of pilot opinion surveys and part task simulator studies.

  17. Cockpit display of hazardous weather information

    NASA Technical Reports Server (NTRS)

    Hansman, R. John, Jr.; Wanke, Craig

    1989-01-01

    Information transfer and display issues associated with the dissemination of hazardous-weather warnings are studied in the context of wind-shear alerts. Operational and developmental wind-shear detection systems are briefly reviewed. The July 11, 1988 microburst events observed as part of the Denver TDWR operational evaluation are analyzed in terms of information transfer and the effectiveness of the microburst alerts. Information transfer, message content, and display issues associated with microburst alerts generated from ground-based sources (Doppler radars, LLWAS, and PIREPS) are evaluated by means of pilot opinion surveys and part-task simulator studies.

  18. Significance of Thermal Fluvial Incision and Bedrock Transfer due to Ice Advection on Greenland Ice Sheet Topography

    NASA Astrophysics Data System (ADS)

    Crozier, J. A.; Karlstrom, L.; Yang, K.

    2017-12-01

    Ice sheet surface topography reflects a complicated combination of processes that act directly upon the surface and that are products of ice advection. Using recently-available high resolution ice velocity, imagery, ice surface elevation, and bedrock elevation data sets, we seek to determine the domain of significance of two important processes - thermal fluvial incision and transfer of bedrock topography through the ice sheet - on controlling surface topography in the ablation zone. Evaluating such controls is important for understanding how melting of the GIS surface during the melt season may be directly imprinted in topography through supraglacial drainage networks, and indirectly imprinted through its contribution to basal sliding that affects bedrock transfer. We use methods developed by (Karlstrom and Yang, 2016) to identify supraglacial stream networks on the GIS, and use high resolution surface digital elevation models as well as gridded ice velocity and melt rate models to quantify surface processes. We implement a numerically efficient Fourier domain bedrock transfer function (Gudmundsson, 2003) to predict surface topography due to ice advection over bedrock topography obtained from radar. Despite a number of simplifying assumptions, the bedrock transfer function predicts the observed ice sheet surface in most regions of the GIS with ˜90% accuracy, regardless of the presence or absence of supraglacial drainage networks. This supports the hypothesis that bedrock is the most significant driver of ice surface topography on wavelengths similar to ice thickness. Ice surface topographic asymmetry on the GIS is common, with slopes in the direction of ice flow steeper than those faced opposite to ice flow, consistent with bedrock transfer theory. At smaller wavelengths, topography consistent with fluvial erosion by surface hydrologic features is evident. We quantify the effect of ice advection versus fluvial thermal erosion on supraglacial longitudinal stream

  19. Cross-Modality Information Transfer: A Hypothesis about the Relationship among Prehistoric Cave Paintings, Symbolic Thinking, and the Emergence of Language.

    PubMed

    Miyagawa, Shigeru; Lesure, Cora; Nóbrega, Vitor A

    2018-01-01

    Early modern humans developed mental capabilities that were immeasurably greater than those of non-human primates. We see this in the rapid innovation in tool making, the development of complex language, and the creation of sophisticated art forms, none of which we find in our closest relatives. While we can readily observe the results of this high-order cognitive capacity, it is difficult to see how it could have developed. We take up the topic of cave art and archeoacoustics, particularly the discovery that cave art is often closely connected to the acoustic properties of the cave chambers in which it is found. Apparently, early modern humans were able to detect the way sound reverberated in these chambers, and they painted artwork on surfaces that were acoustic "hot spots," i.e., suitable for generating echoes. We argue that cave art is a form of cross-modality information transfer, in which acoustic signals are transformed into symbolic visual representations. This form of information transfer across modalities is an instance of how the symbolic mind of early modern humans was taking shape into concrete, externalized language. We also suggest that the earliest rock art found in Africa may constitute one of the first fossilized proxies for the expression of full-fledged human linguistic behavior.

  20. Energy transfer and motion synchronization between mechanical oscillators through microhydrodynamic coupling

    NASA Astrophysics Data System (ADS)

    Wan, Yu; Jin, Kai; Ahmad, Talha J.; Black, Michael J.; Xu, Zhiping

    2017-03-01

    Fluidic environment is encountered for mechanical components in many circumstances, which not only damps the oscillation but also modulates their dynamical behaviors through hydrodynamic interactions. In this study, we examine energy transfer and motion synchronization between two mechanical micro-oscillators by performing thermal lattice-Boltzmann simulations. The coefficient of inter-oscillator energy transfer is measured to quantify the strength of microhydrodynamic coupling, which depends on their distance and fluid properties such as density and viscosity. Synchronized motion of the oscillators is observed in the simulations for typical parameter sets in relevant applications, with the formation and loss of stable anti-phase synchronization controlled by the oscillating frequency, amplitude, and hydrodynamic coupling strength. The critical ranges of key parameters to assure efficient energy transfer or highly synchronized motion are predicted. These findings could be used to advise mechanical design of passive and active devices that operate in fluid.

  1. Gene transfers can date the tree of life.

    PubMed

    Davín, Adrián A; Tannier, Eric; Williams, Tom A; Boussau, Bastien; Daubin, Vincent; Szöllősi, Gergely J

    2018-05-01

    Biodiversity has always been predominantly microbial, and the scarcity of fossils from bacteria, archaea and microbial eukaryotes has prevented a comprehensive dating of the tree of life. Here, we show that patterns of lateral gene transfer deduced from an analysis of modern genomes encode a novel and abundant source of information about the temporal coexistence of lineages throughout the history of life. We use state-of-the-art species tree-aware phylogenetic methods to reconstruct the history of thousands of gene families and demonstrate that dates implied by gene transfers are consistent with estimates from relaxed molecular clocks in Bacteria, Archaea and Eukarya. We present the order of speciations according to lateral gene transfer data calibrated to geological time for three datasets comprising 40 genomes for Cyanobacteria, 60 genomes for Archaea and 60 genomes for Fungi. An inspection of discrepancies between transfers and clocks and a comparison with mammalian fossils show that gene transfer in microbes is potentially as informative for dating the tree of life as the geological record in macroorganisms.

  2. Symbolic phase transfer entropy method and its application

    NASA Astrophysics Data System (ADS)

    Zhang, Ningning; Lin, Aijing; Shang, Pengjian

    2017-10-01

    In this paper, we introduce symbolic phase transfer entropy (SPTE) to infer the direction and strength of information flow among systems. The advantages of the proposed method are investigated by simulations on synthetic signals and real-world data. We demonstrate that symbolic phase transfer entropy is a robust and efficient tool to infer the information flow between complex systems. Based on the study of the synthetic data, we find a significant advantage of SPTE is its reduced sensitivity to noise. In addition, SPTE requires less amount of data than symbolic transfer entropy(STE). We analyze the direction and strength of information flow between six stock markets during the period from 2006 to 2016. The results indicate that the information flow among stocks varies over different periods. We also find that the interaction network pattern among stocks undergoes hierarchial reorganization with transition from one period to another. It is shown that the clusters are mainly classified according to period, and then by region. The stocks during the same time period are shown to drop into the same cluster.

  3. Evaluation of Hose in Hose transfer line service life

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    EAGLE, O.H.

    This document presents a determination for the amount of expected service life from Hose-in-Hose Transfer Lines based on vendor information and past HIHTL experience. Based on the information presented in this report and referenced documentation, we conclude the service life of the inner hose establishes the limits of service life for the finished assemblies. Since the process and environmental conditions to which the transfer line is subjected will not adversely affect the hose, the effective service life is that stated by the vendor--three years from the date of initial transfer. Transfer line assemblies have a shelf life of seven yearsmore » from the date of hose manufacture, if stored in accordance with Section 2.1. This evaluation provides documentation showing that a three year service life has been justified. In the event that transfer lines are to be operated after three years from the date of initial transfer and within the shelf life of seven years, they must be reevaluated for their ability to perform intended functions.« less

  4. 78 FR 59772 - Proposed Information Collection (Evidence for Transfer of Entitlement of Education Benefits...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-27

    ... (Evidence for Transfer of Entitlement of Education Benefits) Activity: Comment Request AGENCY: Veterans Benefits Administration, Department of Veterans Affairs. ACTION: Notice. SUMMARY: The Veterans Benefits... receive education benefits under the transfer of entitlement provision of law. Affected Public...

  5. 75 FR 68035 - Proposed Information Collection (Evidence for Transfer of Entitlement of Education Benefits...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-04

    ... (Evidence for Transfer of Entitlement of Education Benefits) Activity: Comment Request AGENCY: Veterans Benefits Administration, Department of Veterans Affairs. ACTION: Notice. SUMMARY: The Veterans Benefits... receive education benefits under the transfer of entitlement provision of law. Affected Public...

  6. Quantifying Particle Numbers and Mass Flux in Drifting Snow

    NASA Astrophysics Data System (ADS)

    Crivelli, Philip; Paterna, Enrico; Horender, Stefan; Lehning, Michael

    2016-12-01

    We compare two of the most common methods of quantifying mass flux, particle numbers and particle-size distribution for drifting snow events, the snow-particle counter (SPC), a laser-diode-based particle detector, and particle tracking velocimetry based on digital shadowgraphic imaging. The two methods were correlated for mass flux and particle number flux. For the SPC measurements, the device was calibrated by the manufacturer beforehand. The shadowgrapic imaging method measures particle size and velocity directly from consecutive images, and before each new test the image pixel length is newly calibrated. A calibration study with artificially scattered sand particles and glass beads provides suitable settings for the shadowgraphical imaging as well as obtaining a first correlation of the two methods in a controlled environment. In addition, using snow collected in trays during snowfall, several experiments were performed to observe drifting snow events in a cold wind tunnel. The results demonstrate a high correlation between the mass flux obtained for the calibration studies (r ≥slant 0.93) and good correlation for the drifting snow experiments (r ≥slant 0.81). The impact of measurement settings is discussed in order to reliably quantify particle numbers and mass flux in drifting snow. The study was designed and performed to optimize the settings of the digital shadowgraphic imaging system for both the acquisition and the processing of particles in a drifting snow event. Our results suggest that these optimal settings can be transferred to different imaging set-ups to investigate sediment transport processes.

  7. Talker-specificity and adaptation in quantifier interpretation

    PubMed Central

    Yildirim, Ilker; Degen, Judith; Tanenhaus, Michael K.; Jaeger, T. Florian

    2015-01-01

    Linguistic meaning has long been recognized to be highly context-dependent. Quantifiers like many and some provide a particularly clear example of context-dependence. For example, the interpretation of quantifiers requires listeners to determine the relevant domain and scale. We focus on another type of context-dependence that quantifiers share with other lexical items: talker variability. Different talkers might use quantifiers with different interpretations in mind. We used a web-based crowdsourcing paradigm to study participants’ expectations about the use of many and some based on recent exposure. We first established that the mapping of some and many onto quantities (candies in a bowl) is variable both within and between participants. We then examined whether and how listeners’ expectations about quantifier use adapts with exposure to talkers who use quantifiers in different ways. The results demonstrate that listeners can adapt to talker-specific biases in both how often and with what intended meaning many and some are used. PMID:26858511

  8. Quantifying Additive Interactions of the Osmolyte Proline with Individual Functional Groups of Proteins: Comparisons with Urea and Glycine Betaine, Interpretation of m-Values

    PubMed Central

    Diehl, Roger C.; Guinn, Emily J.; Capp, Michael W.; Tsodikov, Oleg V.; Record, M. Thomas

    2013-01-01

    To quantify interactions of the osmolyte L-proline with protein functional groups and predict its effects on protein processes, we use vapor pressure osmometry to determine chemical potential derivatives dµ2/dm3 = µ23 quantifying preferential interactions of proline (component 3) with 21 solutes (component 2) selected to display different combinations of aliphatic or aromatic C, amide, carboxylate, phosphate or hydroxyl O, and/or amide or cationic N surface. Solubility data yield µ23 values for 4 less-soluble solutes. Values of µ23 are dissected using an ASA-based analysis to test the hypothesis of additivity and obtain α-values (proline interaction potentials) for these eight surface types and three inorganic ions. Values of µ23 predicted from these α-values agree with experiment, demonstrating additivity. Molecular interpretation of α-values using the solute partitioning model yields partition coefficients (Kp) quantifying the local accumulation or exclusion of proline in the hydration water of each functional group. Interactions of proline with native protein surface and effects of proline on protein unfolding are predicted from α-values and ASA information and compared with experimental data, with results for glycine betaine and urea, and with predictions from transfer free energy analysis. We conclude that proline stabilizes proteins because of its unfavorable interactions with (exclusion from) amide oxygens and aliphatic hydrocarbon surface exposed in unfolding, and that proline is an effective in vivo osmolyte because of the osmolality increase resulting from its unfavorable interactions with anionic (carboxylate and phosphate) and amide oxygens and aliphatic hydrocarbon groups on the surface of cytoplasmic proteins and nucleic acids. PMID:23909383

  9. TRANSFERENCE BEFORE TRANSFERENCE.

    PubMed

    Bonaminio, Vincenzo

    2017-10-01

    This paper is predominantly a clinical presentation that describes the transmigration of one patient's transference to another, with the analyst functioning as a sort of transponder. It involves an apparently accidental episode in which there was an unconscious intersection between two patients. The author's aim is to show how transference from one case may affect transference in another, a phenomenon the author calls transference before transference. The author believes that this idea may serve as a tool for understanding the unconscious work that takes place in the clinical situation. In a clinical example, the analyst finds himself caught up in an enactment involving two patients in which he becomes the medium of what happens in session. © 2017 The Psychoanalytic Quarterly, Inc.

  10. 75 FR 7551 - Transfer of Accumulated Benefit Payments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-22

    ... Transfer of Accumulated Benefit Payments AGENCY: Social Security Administration (SSA). ACTION: Final rule... that capacity to transfer accumulated benefit payments and interest directly to a beneficiary if we.... For information on eligibility or filing for benefits, call our national toll-free number, 1-800-772...

  11. Quantifying conditional risks for water and energy systems using climate information

    NASA Astrophysics Data System (ADS)

    Lall, U.

    2016-12-01

    There has been a growing recognition of the multi-scale spatio-temporal organization of climate dynamics, and its implications for predictable, structured risk exposure to populations and infrastructure systems. At the most base level is an understanding that there are some identifiable climate modes, such as ENSO, that are associated with such outcomes. This has led to the emergence of a small cottage industry of analysts who relate different "climate indices" to specific regional outcomes. Such efforts and the associated media interest in these simplified "stories" have led to an increasing appreciation of the phenomenon, and some formal and informal efforts at decision making using such information. However, as was demonstrated through the 2014-16 El Nino forecasting season, many climate scientists over-emphasized the potential risks, while others cautioned the media as to the caveats and uncertainties associated with assuming that the forecasts of ENSO and the expected teleconnections may pan out. At least in certain sectors and regions, significant efforts or expectations as to outcomes were put in place, and some were beneficial, while others failed to manifest. Climate informed predictions for water and energy systems can be thought of as efforts to infer conditional distributions of specific outcomes given information on climate state. Invariably, the climate state may be presented as a very high dimensional spatial set of variables, with limited temporal sampling, while the water and energy attributes may be regional and constitute a much smaller dimension. One may, of course, be interested in the fact that the same climate state may lead to synchronous positive and negative effects across many locations, as may be expected under mid-latitude stationary and transient wave interaction. In this talk, I will provide examples of a few modern statistical and machine learning tools that allow a decomposition of the high dimensional climate state and its relation

  12. Quantifying the range of cross-correlated fluctuations using a q- L dependent AHXA coefficient

    NASA Astrophysics Data System (ADS)

    Wang, Fang; Wang, Lin; Chen, Yuming

    2018-03-01

    Recently, based on analogous height cross-correlation analysis (AHXA), a cross-correlation coefficient ρ×(L) has been proposed to quantify the levels of cross-correlation on different temporal scales for bivariate series. A limitation of this coefficient is that it cannot capture the full information of cross-correlations on amplitude of fluctuations. In fact, it only detects the cross-correlation at a specific order fluctuation, which might neglect some important information inherited from other order fluctuations. To overcome this disadvantage, in this work, based on the scaling of the qth order covariance and time delay L, we define a two-parameter dependent cross-correlation coefficient ρq(L) to detect and quantify the range and level of cross-correlations. This new version of ρq(L) coefficient leads to the formation of a ρq(L) surface, which not only is able to quantify the level of cross-correlations, but also allows us to identify the range of fluctuation amplitudes that are correlated in two given signals. Applications to the classical ARFIMA models and the binomial multifractal series illustrate the feasibility of this new coefficient ρq(L) . In addition, a statistical test is proposed to quantify the existence of cross-correlations between two given series. Applying our method to the real life empirical data from the 1999-2000 California electricity market, we find that the California power crisis in 2000 destroys the cross-correlation between the price and the load series but does not affect the correlation of the load series during and before the crisis.

  13. Information sensitivity functions to assess parameter information gain and identifiability of dynamical systems.

    PubMed

    Pant, Sanjay

    2018-05-01

    A new class of functions, called the 'information sensitivity functions' (ISFs), which quantify the information gain about the parameters through the measurements/observables of a dynamical system are presented. These functions can be easily computed through classical sensitivity functions alone and are based on Bayesian and information-theoretic approaches. While marginal information gain is quantified by decrease in differential entropy, correlations between arbitrary sets of parameters are assessed through mutual information. For individual parameters, these information gains are also presented as marginal posterior variances, and, to assess the effect of correlations, as conditional variances when other parameters are given. The easy to interpret ISFs can be used to (a) identify time intervals or regions in dynamical system behaviour where information about the parameters is concentrated; (b) assess the effect of measurement noise on the information gain for the parameters; (c) assess whether sufficient information in an experimental protocol (input, measurements and their frequency) is available to identify the parameters; (d) assess correlation in the posterior distribution of the parameters to identify the sets of parameters that are likely to be indistinguishable; and (e) assess identifiability problems for particular sets of parameters. © 2018 The Authors.

  14. Informal Care and the Division of End-of-Life Transfers

    ERIC Educational Resources Information Center

    Brown, Meta

    2006-01-01

    Unmarried parents in the AHEAD study derive the majority of their long-term care hours from their children, and child caregivers are generally unpaid. This paper examines the extent to which the division of end-of-life transfers compensates caregiving children. In a model of siblings' altruistic contribution of care to a shared parent, the…

  15. Transferring Technology to Industry

    NASA Technical Reports Server (NTRS)

    Wolfenbarger, J. Ken

    2006-01-01

    This slide presentation reviews the technology transfer processes in which JPL has been involved to assist in transferring the technology derived from aerospace research and development to industry. California Institute of Technology (CalTech), the organization that runs JPL, is the leading institute in patents for all U.S. universities. There are several mechanisms that are available to JPL to inform industry of these technological advances: (1) a dedicated organization at JPL, National Space Technology Applications (NSTA), (2) Tech Brief Magazine, (3) Spinoff magazine, and (4) JPL publications. There have also been many start-up organizations and businesses from CalTech.

  16. Entropy Information of Cardiorespiratory Dynamics in Neonates during Sleep.

    PubMed

    Lucchini, Maristella; Pini, Nicolò; Fifer, William P; Burtchen, Nina; Signorini, Maria G

    2017-05-01

    Sleep is a central activity in human adults and characterizes most of the newborn infant life. During sleep, autonomic control acts to modulate heart rate variability (HRV) and respiration. Mechanisms underlying cardiorespiratory interactions in different sleep states have been studied but are not yet fully understood. Signal processing approaches have focused on cardiorespiratory analysis to elucidate this co-regulation. This manuscript proposes to analyze heart rate (HR), respiratory variability and their interrelationship in newborn infants to characterize cardiorespiratory interactions in different sleep states (active vs. quiet). We are searching for indices that could detect regulation alteration or malfunction, potentially leading to infant distress. We have analyzed inter-beat (RR) interval series and respiration in a population of 151 newborns, and followed up with 33 at 1 month of age. RR interval series were obtained by recognizing peaks of the QRS complex in the electrocardiogram (ECG), corresponding to the ventricles depolarization. Univariate time domain, frequency domain and entropy measures were applied. In addition, Transfer Entropy was considered as a bivariate approach able to quantify the bidirectional information flow from one signal (respiration) to another (RR series). Results confirm the validity of the proposed approach. Overall, HRV is higher in active sleep, while high frequency (HF) power characterizes more quiet sleep. Entropy analysis provides higher indices for SampEn and Quadratic Sample entropy (QSE) in quiet sleep. Transfer Entropy values were higher in quiet sleep and point to a major influence of respiration on the RR series. At 1 month of age, time domain parameters show an increase in HR and a decrease in variability. No entropy differences were found across ages. The parameters employed in this study help to quantify the potential for infants to adapt their cardiorespiratory responses as they mature. Thus, they could be useful

  17. New Routes To Transfer. The Advisor. November 2001

    ERIC Educational Resources Information Center

    British Columbia Council on Admissions and Transfer, 2001

    2001-01-01

    The Advisor provides important information or "system alerts," in user-friendly format and language, on issues and changes affecting admissions and transfer. This document outlines new transfer possibilities in academic arts and science programs, and business diploma programs -- the two largest programs offered by the colleges,…

  18. KSC Tech Transfer News, Volume 5, No. 2

    NASA Technical Reports Server (NTRS)

    Nichols, James D.

    2013-01-01

    Kennedy Tech Transfer News is the semiannual magazine of the Innovative Partnerships Program Office at NASA Kennedy Space Center in Cape Canaveral, Florida. This magazine seeks to inform and educate cMI servant and Contractor personnel at Kennedy about actively participating in achieving NASA's technology transfer goals

  19. Transfer entropy analysis of maternal and fetal heart rate coupling.

    PubMed

    Marzbanrad, Faezeh; Kimura, Yoshitaka; Endo, Miyuki; Palaniswami, Marimuthu; Khandoker, Ahsan H

    2015-01-01

    Although evidence of the short term relationship between maternal and fetal heart rates has been found in previous model-based studies, knowledge about the mechanism and patterns of the coupling during gestation is still limited. In this study, a model-free method based on Transfer Entropy (TE) was applied to quantify the maternal-fetal heart rate couplings in both directions. Furthermore, analysis of the lag at which TE was maximum and its changes throughout gestation, provided more information about the mechanism of coupling and its latency. Experimental results based on fetal electrocardiograms (fECGs) and maternal ECG showed the evidence of coupling for 62 out of 65 healthy mothers and fetuses in each direction, by statistically validating against the surrogate pairs. The fetuses were divided into three gestational age groups: early (16-25 weeks), mid (26-31 weeks) and late (32-41 weeks) gestation. The maximum TE from maternal to fetal heart rate significantly increased from early to mid gestation, while the coupling delay on both directions decreased significantly from mid to late gestation. These changes occur concomitant with the maturation of the fetal sensory and autonomic nervous systems with advancing gestational age. In conclusion, the application of TE with delays revealed detailed information about the changes in fetal-maternal heart rate coupling strength and latency throughout gestation, which could provide novel clinical markers of fetal development and well-being.

  20. Patients' and relatives' experiences of transfer from intensive care unit to wards.

    PubMed

    Cullinane, James P; Plowright, Catherine I

    2013-11-01

    This literature review looks at the evidence around transferring patients from intensive care units (ICU) to wards. The literature informs us that patients and their families experience problems when being transferred from an ICU environment and that this increases overall anxiety. The effects of surviving critical illness often have a profound psychological impact on patients and families This study examines the experiences of adult patients, and their families, following their transfer from the ICU to the ward. Five themes emerged from this literature review: physical responses, psychological responses, information and communication, safety and security, and the needs of relatives. This review reminds us that these problems can be reduced if information and communication around time of transfers were improved. As critical care nurses it is essential that we prepare patients and families for transfer to wards. © 2013 British Association of Critical Care Nurses.