Sample records for quantifying laser damage

  1. Quantifying thermal modifications on laser welded skin tissue

    NASA Astrophysics Data System (ADS)

    Tabakoglu, Hasim Ö.; Gülsoy, Murat

    2011-02-01

    Laser tissue welding is a potential medical treatment method especially on closing cuts implemented during any kind of surgery. Photothermal effects of laser on tissue should be quantified in order to determine optimal dosimetry parameters. Polarized light and phase contrast techniques reveal information about extend of thermal change over tissue occurred during laser welding application. Change in collagen structure in skin tissue stained with hematoxilen and eosin samples can be detected. In this study, three different near infrared laser wavelengths (809 nm, 980 nm and 1070 nm) were compared for skin welding efficiency. 1 cm long cuts were treated spot by spot laser application on Wistar rats' dorsal skin, in vivo. In all laser applications, 0.5 W of optical power was delivered to the tissue, 5 s continuously, resulting in 79.61 J/cm2 energy density (15.92 W/cm2 power density) for each spot. The 1st, 4th, 7th, 14th, and 21st days of recovery period were determined as control days, and skin samples needed for histology were removed on these particular days. The stained samples were examined under a light microscope. Images were taken with a CCD camera and examined with imaging software. 809 Nm laser was found to be capable of creating strong full-thickness closure, but thermal damage was evident. The thermal damage from 980 nm laser welding was found to be more tolerable. The results showed that 1070 nm laser welding produced noticeably stronger bonds with minimal scar formation.

  2. Enhanced Damage-Resistant Optics for Spaceflight Laser Systems: Workshop findings and recommendations

    NASA Technical Reports Server (NTRS)

    Schulze, Norman; Cimolino, Marc; Guenther, Arthur; Mcminn, Ted; Rainer, Frank; Schmid, Ansgar; Seitel, Steven C.; Soileau, M. J.; Theon, John S.; Walz, William

    1991-01-01

    NASA has defined a program to address critical laser-induced damage issues peculiar to its remote sensing systems. The Langley Research Center (LaRC), with input from the Goddard Space Flight Center (GSFC), has developed a program plan focusing on the certification of optical materials for spaceflight applications and the development of techniques to determine the reliability of such materials under extended laser exposures. This plan involves cooperative efforts between NASA and optics manufacturers to quantify the performance of optical materials for NASA systems and to ensure NASA's continued application of the highest quality optics possible for enhanced system reliability. A review panel was organized to assess NASA's optical damage concerns and to evaluate the effectiveness of the LaRC proposed program plan. This panel consisted of experts in the areas of laser-induced damage, optical coating manufacture, and the design and development of laser systems for space. The panel was presented information on NASA's current and planned laser remote sensing programs, laser-induced damage problems already encountered in NASA systems, and the proposed program plan to address these issues. Additionally, technical presentations were made on the state of the art in damage mechanisms, optical materials testing, and issues of coating manufacture germane to laser damage.

  3. Special Section Guest Editorial: Laser Damage

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gruzdev, Vitaly E.; Shinn, Michelle D.

    2012-11-09

    Laser damage of optical materials, first reported in 1964, continues to limit the output energy and power of pulsed and continuous-wave laser systems. In spite of some 48 years of research in this area, interest from the international laser community to laser damage issues remains at a very high level and does not show any sign of decreasing. Moreover, it grows with the development of novel laser systems, for example, ultrafast and short-wavelength lasers that involve new damage effects and specific mechanisms not studied before. This interest is evident from the high level of attendance and presentations at the annualmore » SPIE Laser Damage Symposium (aka, Boulder Damage Symposium) that has been held in Boulder, Colorado, since 1969. This special section of Optical Engineering is the first one devoted to the entire field of laser damage rather than to a specific part. It is prepared in response to growing interest from the international laser-damage community. Some papers in this special section were presented at the Laser Damage Symposium; others were submitted in response to the general call for papers for this special section. The 18 papers compiled into this special section represent many sides of the broad field of laser-damage research. They consider theoretical studies of the fundamental mechanisms of laser damage including laser-driven electron dynamics in solids (O. Brenk and B. Rethfeld; A. Nikiforov, A. Epifanov, and S. Garnov; T. Apostolova et al.), modeling of propagation effects for ultrashort high-intensity laser pulses (J. Gulley), an overview of mechanisms of inclusion-induced damage (M. Koldunov and A. Manenkov), the formation of specific periodic ripples on a metal surface by femtosecond laser pulses (M. Ahsan and M. Lee), and the laser-plasma effects on damage in glass (Y. Li et al). Material characterization is represented by the papers devoted to accurate and reliable measurements of absorption with special emphasis on thin films (C. M

  4. CMO YAG laser damage test facility

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hue, J.; Dijon, J.; Lyan, P.

    1996-12-31

    The CMO YAG laser damage test facility, which is equipped with a 30Hz laser, is presented in this paper. The main points are described below: (1) The characteristics of the laser beam and the in situ damage detection technique (a scattered light measurement system) are perfectly suited to work up to the frequency of the laser. They are monitored in real time, and work at three wavelengths: 1064 nm, 532 nm, 355 nm. (2) With this same shutter, it is possible to automatically stop the laser on the pulse which induces the first damages. These automatic capabilities enable the samplesmore » to be tested quickly. (3) A Nomarski microscope supplied with a 16-bit CCD camera enables the test sites to be photographed before and after the laser interaction. Image processing enables the authors to extract the first damages. before and after the laser interaction. Image processing enables them to extract the first damages. (4) Six pulse widths are available (between 3ns and 13ns). Therefore, with all these characterization tools, many kinds of laser tests may be considered. These different features are illustrated by experimental results (1-on-1 test or R-on-1 test).« less

  5. Laser-induced cartilage damage: an ex-vivo model using confocal microscopy

    NASA Astrophysics Data System (ADS)

    Frenz, Martin; Zueger, Benno J.; Monin, D.; Weiler, C.; Mainil-Varlet, P. M.; Weber, Heinz P.; Schaffner, Thomas

    1999-06-01

    Although there is an increasing popularity of lasers in orthopedic surgery, there is a growing concern about negative side effects of this therapy e.g. prolonged restitution time, radiation damage to adjacent cartilage or depth effects like bone necrosis. Despite case reports and experimental investigations over the last few years little is known about the extent of acute cartilage damage induced by different lasers types and energies. Histological examination offers only limited insights in cell viability and metabolism. Ho:YAG and Er:YAG lasers emitting at 2.1 micrometer and 2.94 micrometer, respectively, are ideally suited for tissue treatment because these wavelengths are strongly absorbed in water. The Purpose of the present study is to evaluate the effect of laser type and energy on chondrocyte viability in an ex vivo model. Free running Er:YAG (E equals 100 and 150 mJ) and Ho:YAG (E equals 500 and 800 mJ) lasers were used at different energy levels using a fixed pulse length of 400 microseconds. The energy was delivered at 8 Hz through optical fibers. Fresh bovine hyaline cartilage samples were mounted in a water bath at room temperature and the fiber was positioned at 30 degree and 180 degree angles relative to the tissue surface. After laser irradiation the samples were assessed by a life-dead cell viability test using a confocal microscope and by standard histology. Thermal damage was much deeper with Ho:YAG (up to 1800 micrometer) than with the Er:YAG laser (up to 70 micrometer). The cell viability test revealed a damage zone about twice the one determined by standard histology. Confocal microscopy is a powerful tool for assessing changes in tissue structure after laser treatment. In addition this technique allows to quantify these alterations without necessitating time consuming and expensive animal experiments.

  6. Boulder damage symposium annual thin film laser damage competition

    DOE PAGES

    Stolz, Christopher J.

    2012-11-28

    Optical instruments and laser systems are often fluence-limited by multilayer thin films deposited on the optical surfaces. When comparing publications within the laser damage literature, there can be confusing and conflicting laser damage results. This is due to differences in testing protocols between research groups studying very different applications. In this series of competitions, samples from multiple vendors are compared under identical testing parameters and a single testing service. Unlike a typical study where a hypothesis is tested within a well-controlled experiment with isolated variables, this competition isolates the laser damage testing variables so that trends can be observed betweenmore » different deposition processes, coating materials, cleaning techniques, and multiple coating suppliers. The resulting series of damage competitions has also been designed to observe general trends of damage morphologies and mechanisms over a wide range of coating types (high reflector and antireflector), wavelengths (193 to 1064 nm), and pulse lengths (180 fs to 13 ns). A double blind test assured sample and submitter anonymity were used in each of the competitions so only a summary of the deposition process, coating materials, layer count and spectral results are presented. Laser resistance was strongly affected by substrate cleaning, coating deposition method, and coating material selection whereas layer count and spectral properties had minimal impact.« less

  7. Application of Laser Based Ultrasound for NDE of Damage in Thick Stitched Composites

    NASA Technical Reports Server (NTRS)

    Anastasi, Robert F.; Friedman, Adam D.; Hinders, Mark K.; Madaras, Eric I.

    1997-01-01

    As design engineers implement new composite systems such as thick, load bearing composite structures, they must have certifiable confidence in structure s durability and worthiness. This confidence builds from understanding the structural response and failure characteristics of simple components loaded in testing machines to tests on full scale sections. Nondestructive evaluation is an important element which can provide quantitative information on the damage initiation, propagation, and final failure modes for the composite structural components. Although ultrasound is generally accepted as a test method, the use of conventional ultrasound for in-situ monitoring of damage during tests of large structures is not practical. The use of lasers to both generate and detect ultrasound extends the application of ultrasound to in- situ sensing of damage in a deformed structure remotely and in a non-contact manner. The goal of the present research is to utilize this technology to monitor damage progression during testing. The present paper describes the application of laser based ultrasound to quantify damage in thick stitched composite structural elements to demonstrate the method. This method involves using a Q-switched laser to generate a rapid, local linear thermal strain on the surface of the structure. This local strain causes the generation of ultrasonic waves into the material. A second laser used with a Fabry-Perot interferometer detects the surface deflections. The use of fiber optics provides for eye safety and a convenient method of delivering the laser over long distances to the specimens. The material for these structural elements is composed of several stacks of composite material assembled together by stitching through the laminate thickness that ranging from 0.5 to 0.8 inches. The specimens used for these nondestructive evaluation studies had either impact damage or skin/stiffener interlaminar failure. Although little or no visible surface damage existed

  8. Laser damage mechanisms in conductive widegap semiconductor films

    DOE PAGES

    Yoo, Jae-Hyuck; Menor, Marlon G.; Adams, John J.; ...

    2016-07-25

    Here, laser damage mechanisms of two conductive wide-bandgap semiconductor films - indium tin oxide (ITO) and silicon doped GaN (Si:GaN) were studied via microscopy, spectroscopy, photoluminescence (PL), and elemental analysis. Nanosecond laser pulse exposures with a laser photon energy (1.03 eV, 1064 nm) smaller than the conductive films bandgaps were applied and radically different film damage morphologies were produced. The laser damaged ITO film exhibited deterministic features of thermal degradation. In contrast, laser damage in the Si:GaN film resulted in highly localized eruptions originating at interfaces. For ITO, thermally driven damage was related to free carrier absorption and, for GaN,more » carbon complexes were proposed as potential damage precursors or markers.« less

  9. Laser-Induced Thermal Damage of Skin

    DTIC Science & Technology

    1977-12-01

    identify by block number) Skin Burns Skin Model Laser Effects \\Thermal Predictions 20 ABSTRACT (Continue on reverse side it necessary and identify by...block number) A computerized model was developed for predicting thermal damage of skin by laser exposures. Thermal, optical, and physiological data are...presented for the model. Model predictions of extent of irreversible damage were compared with histologic determinations of the extent of damage

  10. Numerical analysis of laser ablation and damage in glass with multiple picosecond laser pulses.

    PubMed

    Sun, Mingying; Eppelt, Urs; Russ, Simone; Hartmann, Claudia; Siebert, Christof; Zhu, Jianqiang; Schulz, Wolfgang

    2013-04-08

    This study presents a novel numerical model for laser ablation and laser damage in glass including beam propagation and nonlinear absorption of multiple incident ultrashort laser pulses. The laser ablation and damage in the glass cutting process with a picosecond pulsed laser was studied. The numerical results were in good agreement with our experimental observations, thereby revealing the damage mechanism induced by laser ablation. Beam propagation effects such as interference, diffraction and refraction, play a major role in the evolution of the crater structure and the damage region. There are three different damage regions, a thin layer and two different kinds of spikes. Moreover, the electronic damage mechanism was verified and distinguished from heat modification using the experimental results with different pulse spatial overlaps.

  11. Thin film femtosecond laser damage competition

    NASA Astrophysics Data System (ADS)

    Stolz, Christopher J.; Ristau, Detlev; Turowski, Marcus; Blaschke, Holger

    2009-10-01

    In order to determine the current status of thin film laser resistance within the private, academic, and government sectors, a damage competition was started at the 2008 Boulder Damage Symposium. This damage competition allows a direct comparison of the current state of the art of high laser resistance coatings since they are tested using the same damage test setup and the same protocol. In 2009 a high reflector coating was selected at a wavelength of 786 nm at normal incidence at a pulse length of 180 femtoseconds. A double blind test assured sample and submitter anonymity so only a summary of the results are presented here. In addition to the laser resistance results, details of deposition processes, coating materials and layer count, and spectral results will also be shared.

  12. MELBA: a fully customizable laser for damage experiments

    NASA Astrophysics Data System (ADS)

    Veinhard, Matthieu; Bonville, Odile; Courchinoux, Roger; Parreault, Romain; Natoli, Jean-Yves; Lamaignère, Laurent

    2017-11-01

    A millimetric aperture Nd:glass laser system has been designed and constructed at the CEA-CESTA. Its aim is to best mimic the laser conditions that can be found in inertial confinement fusion facilities. It is therefore used to study the main phenomena that prevents these lasers to work at their maximum power: the laser induced damage of the optical components. The combination of temporal and spatial modulators provides, every minute, a 6 J, 7 mm, 351 nm homogeneous beam at the fused silica sample location. This proceeding illustrates the capacity of the facility over two experiments: the study of damage initiation and the growth of laser damage sites on fused silica, up to millimetric scales

  13. Carbon dioxide laser polishing of fused silica surfaces for increased laser-damage resistance at 1064 nm.

    PubMed

    Temple, P A; Lowdermilk, W H; Milam, D

    1982-09-15

    Mechanically polished fused silica surfaces were heated with continuous-wave CO(2) laser radiation. Laser-damage thresholds of the surfaces were measured with 1064-nm 9-nsec pulses focused to small spots and with large-spot, 1064-nm, 1-nsec irradiation. A sharp transition from laser-damage-prone to highly laser-damage-resistant took place over a small range in CO(2) laser power. The transition to high damage resistance occurred at a silica surface temperature where material softening began to take place as evidenced by the onset of residual strain in the CO(2) laser-processed part. The small-spot damage measurements show that some CO(2) laser-treated surfaces have a local damage threshold as high as the bulk damage threshold of SiO(2). On some CO(2) laser-treated surfaces, large-spot damage thresholds were increased by a factor of 3-4 over thresholds of the original mechanically polished surface. These treated parts show no obvious change in surface appearance as seen in bright-field, Nomarski, or total internal reflection microscopy. They also show little change in transmissive figure. Further, antireflection films deposited on CO(2) laser-treated surfaces have thresholds greater than the thresholds of antireflection films on mechanically polished surfaces.

  14. Experimental research on femto-second laser damaging array CCD cameras

    NASA Astrophysics Data System (ADS)

    Shao, Junfeng; Guo, Jin; Wang, Ting-feng; Wang, Ming

    2013-05-01

    Charged Coupled Devices (CCD) are widely used in military and security applications, such as airborne and ship based surveillance, satellite reconnaissance and so on. Homeland security requires effective means to negate these advanced overseeing systems. Researches show that CCD based EO systems can be significantly dazzled or even damaged by high-repetition rate pulsed lasers. Here, we report femto - second laser interaction with CCD camera, which is probable of great importance in future. Femto - second laser is quite fresh new lasers, which has unique characteristics, such as extremely short pulse width (1 fs = 10-15 s), extremely high peak power (1 TW = 1012W), and especially its unique features when interacting with matters. Researches in femto second laser interaction with materials (metals, dielectrics) clearly indicate non-thermal effect dominates the process, which is of vast difference from that of long pulses interaction with matters. Firstly, the damage threshold test are performed with femto second laser acting on the CCD camera. An 800nm, 500μJ, 100fs laser pulse is used to irradiate interline CCD solid-state image sensor in the experiment. In order to focus laser energy onto tiny CCD active cells, an optical system of F/5.6 is used. A Sony production CCDs are chose as typical targets. The damage threshold is evaluated with multiple test data. Point damage, line damage and full array damage were observed when the irradiated pulse energy continuously increase during the experiment. The point damage threshold is found 151.2 mJ/cm2.The line damage threshold is found 508.2 mJ/cm2.The full-array damage threshold is found to be 5.91 J/cm2. Although the phenomenon is almost the same as that of nano laser interaction with CCD, these damage thresholds are substantially lower than that of data obtained from nano second laser interaction with CCD. Then at the same time, the electric features after different degrees of damage are tested with electronic multi

  15. Laser-Induced Damage with Femtosecond Pulses

    NASA Astrophysics Data System (ADS)

    Kafka, Kyle R. P.

    The strong electric fields of focused femtosecond laser pulses lead to non-equilibrium dynamics in materials, which, beyond a threshold intensity, causes laser-induced damage (LID). Such a strongly non-linear and non-perturbative process renders important LID observables like fluence and intensity thresholds and damage morphology (crater) extremely difficult to predict quantitatively. However, femtosecond LID carries a high degree of precision, which has been exploited in various micro/nano-machining and surface engineering applications, such as human eye surgery and super-hydrophobic surfaces. This dissertation presents an array of experimental studies which have measured the damage behavior of various materials under femtosecond irradiation. Precision experiments were performed to produce extreme spatio-temporal confinement of the femtosecond laser-solid damage interaction on monocrystalline Cu, which made possible the first successful direct-benchmarking of LID simulation with realistic damage craters. A technique was developed to produce laser-induced periodic surface structures (LIPSS) in a single pulse (typically a multi-pulse phenomenon), and was used to perform a pump-probe study which revealed asynchronous LIPSS formation on copper. Combined with 1-D calculations, this new experimental result suggests more drastic electron heating than expected. Few-cycle pulses were used to study the LID performance and morphology of commercial ultra-broadband optics, which had not been systematically studied before. With extensive surface analysis, various morphologies were observed, including LIPSS, swelling (blisters), simple craters, and even ring-shaped structures, which varied depending on the coating design, number of pulses, and air/vacuum test environment. Mechanisms leading to these morphologies are discussed, many of which are ultrafast in nature. The applied damage behavior of multi-layer dielectric mirrors was measured and compared between long pulse (150 ps

  16. Laser damage of free-standing nanometer membranes

    NASA Astrophysics Data System (ADS)

    Morimoto, Yuya; Roland, Iännis; Rennesson, Stéphanie; Semond, Fabrice; Boucaud, Philippe; Baum, Peter

    2017-12-01

    Many high-field/attosecond and ultrafast electron diffraction/microscopy experiments on condensed matter require samples in the form of free-standing membranes with nanometer thickness. Here, we report the measurement of the laser-induced damage threshold of 11 different free-standing nanometer-thin membranes of metallic, semiconducting, and insulating materials for 1-ps, 1030-nm laser pulses at 50 kHz repetition rate. We find a laser damage threshold that is very similar to each corresponding bulk material. The measurements also reveal a band gap dependence of the damage threshold as a consequence of different ionization rates. These results establish the suitability of free-standing nanometer membranes for high-field pump-probe experiments.

  17. Infrared laser damage thresholds in corneal tissue phantoms using femtosecond laser pulses

    NASA Astrophysics Data System (ADS)

    Boretsky, Adam R.; Clary, Joseph E.; Noojin, Gary D.; Rockwell, Benjamin A.

    2018-02-01

    Ultrafast lasers have become a fixture in many biomedical, industrial, telecommunications, and defense applications in recent years. These sources are capable of generating extremely high peak power that can cause laser-induced tissue breakdown through the formation of a plasma upon exposure. Despite the increasing prevalence of such lasers, current safety standards (ANSI Z136.1-2014) do not include maximum permissible exposure (MPE) values for the cornea with pulse durations less than one nanosecond. This study was designed to measure damage thresholds in corneal tissue phantoms in the near-infrared and mid-infrared to identify the wavelength dependence of laser damage thresholds from 1200-2500 nm. A high-energy regenerative amplifier and optical parametric amplifier outputting 100 femtosecond pulses with pulse energies up to 2 mJ were used to perform exposures and determine damage thresholds in transparent collagen gel tissue phantoms. Three-dimensional imaging, primarily optical coherence tomography, was used to evaluate tissue phantoms following exposure to determine ablation characteristics at the surface and within the bulk material. The determination of laser damage thresholds in the near-IR and mid-IR for ultrafast lasers will help to guide safety standards and establish the appropriate MPE levels for exposure sensitive ocular tissue such as the cornea. These data will help promote the safe use of ultrafast lasers for a wide range of applications.

  18. Understanding Femtosecond-Pulse Laser Damage through Fundamental Physics Simulations

    NASA Astrophysics Data System (ADS)

    Mitchell, Robert A., III

    It did not take long after the invention of the laser for the field of laser damage to appear. For several decades researchers have been studying how lasers damage materials, both for the basic scientific understanding of highly nonequilibrium processes as well as for industrial applications. Femtosecond pulse lasers create little collateral damage and a readily reproducible damage pattern. They are easily tailored to desired specifications and are particularly powerful and versatile tools, contributing even more industrial interest in the field. As with most long-standing fields of research, many theoretical tools have been developed to model the laser damage process, covering a wide range of complexities and regimes of applicability. However, most of the modeling methods developed are either too limited in spatial extent to model the full morphology of the damage crater, or incorporate only a small subset of the important physics and require numerous fitting parameters and assumptions in order to match values interpolated from experimental data. Demonstrated in this work is the first simulation method capable of fundamentally modeling the full laser damage process, from the laser interaction all the way through to the resolidification of the target, on a large enough scale that can capture the full morphology of the laser damage crater so as to be compared directly to experimental measurements instead of extrapolated values, and all without any fitting parameters. The design, implementation, and testing of this simulation technique, based on a modified version of the particle-in-cell (PIC) method, is presented. For a 60 fs, 1 mum wavelength laser pulse with fluences of 0.5 J/cm 2, 1.0 J/cm2, and 2.0 J/cm2 the resulting laser damage craters in copper are shown and, using the same technique applied to experimental crater morphologies, a laser damage fluence threshold is calculated of 0.15 J/cm2, consistent with current experiments performed under conditions similar

  19. Revision of laser-induced damage threshold evaluation from damage probability data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bataviciute, Gintare; Grigas, Povilas; Smalakys, Linas

    2013-04-15

    In this study, the applicability of commonly used Damage Frequency Method (DFM) is addressed in the context of Laser-Induced Damage Threshold (LIDT) testing with pulsed lasers. A simplified computer model representing the statistical interaction between laser irradiation and randomly distributed damage precursors is applied for Monte Carlo experiments. The reproducibility of LIDT predicted from DFM is examined under both idealized and realistic laser irradiation conditions by performing numerical 1-on-1 tests. A widely accepted linear fitting resulted in systematic errors when estimating LIDT and its error bars. For the same purpose, a Bayesian approach was proposed. A novel concept of parametricmore » regression based on varying kernel and maximum likelihood fitting technique is introduced and studied. Such approach exhibited clear advantages over conventional linear fitting and led to more reproducible LIDT evaluation. Furthermore, LIDT error bars are obtained as a natural outcome of parametric fitting which exhibit realistic values. The proposed technique has been validated on two conventionally polished fused silica samples (355 nm, 5.7 ns).« less

  20. Morphological studies of laser-induced photoacoustic damage

    NASA Astrophysics Data System (ADS)

    Flotte, Thomas J.; Yashima, Yutaka; Watanabe, Shinichi; McAuliffe, Daniel J., Sr.; Jacques, Steven L.

    1990-06-01

    Argon-fluoride excimer laser ablation of stratum comeum causes deeper tissue damage than expected for thermal or photochemical mechanisms, suggesting thatphotoacoustic waves have arole in tissue damage. Laserirradiation (193 nm, 14 ns pulses, 1-2 Hz) attworadiantexposures, 60 and 160 mJ/cm2perpulse was usedto ablate the stratumcomeumofskin. Light and electron microscopy ofimmediate biopsies demonstrated damage to fibroblasts as deep as 88 and 220 jun, respectively, below the ablation site. Ablation throughwaterwas usedtoinertially confine the ablation zone. Partial ablationofs.c. through airproducedno damage, whereas partial ablation through water damaged skin to amean depth of 1 14.5 8.8( Full thickness ablation of s.c. through air and water produced damage zones measuring 192.2 16.2 and 293.0 71.6 rim, respectively (p <0.05). The increased depth ofdamage in the presence ofinertial confinementprovided by the layer of water strongly supports a photoacoustic mechanism ofdamage. The depths ofdamage for thelarge spot, line, and small spots were 43 1 164 urn, 269 96xni, andno damage. The spot size dependence ofthedepthofdamage is consistentwiththe geometric attenuation one would expect to be present from a pressure wave related phenomena. Sequential biopsies were taken over a 7 day period for light and transmission electron microscopy. At 24 hours, there was necrosis of the epidermis and papillary dermis subjacent to the ablation site, with neutrophils surrounding and demarcating the affected area. The necrotic zone sloughedby48 hours. Thereepithelializationwas completeby7 days. The sequenceofrepairis similartoknife wound healing which we have previously studied, and is analogous to other wound healing processes. We have used an experimental model of ArF excimer laser ablation of stratum corneum to investigate laser-induced photoacoustic damage. The evidence for the injury being due to pressure transients is indirectbutcompelling. Whether these pressuretransients are

  1. Thulium fiber laser damage to the ureter

    NASA Astrophysics Data System (ADS)

    Wilson, Christopher R.; Hardy, Luke A.; Irby, Pierce B.; Fried, Nathaniel M.

    2015-07-01

    Our laboratory is studying experimental thulium fiber laser (TFL) as a potential alternative lithotripter to the clinical gold standard Holmium:YAG laser. Safety studies characterizing undesirable Holmium laser-induced damage to ureter tissue have been previously reported. Similarly, this study characterizes TFL induced ureter and stone basket damage. A TFL beam with pulse energy of 35 mJ, pulse duration of 500 μs, and pulse rates of 150-500 Hz was delivered through a 100-μm-core, low-OH, silica optical fiber to the porcine ureter wall, in vitro. Ureter perforation times were measured and gross, histological, and optical coherence tomography images of the ablation zone were acquired. TFL operation at 150, 300, and 500 Hz produced mean ureter perforation times of 7.9, 3.8, and 1.8 s, respectively. Collateral damage averaged 510, 370, and 310 μm. TFL mean perforation time exceeded 1 s at each setting, which is a greater safety margin than previously reported during Holmium laser ureter perforation studies.

  2. Using synchrotron X-ray phase-contrast micro-computed tomography to study tissue damage by laser irradiation.

    PubMed

    Robinson, Alan M; Stock, Stuart R; Soriano, Carmen; Xiao, Xianghui; Richter, Claus-Peter

    2016-11-01

    The aim of this study was to determine if X-ray micro-computed tomography could be used to locate and characterize tissue damage caused by laser irradiation and to describe its advantages over classical histology for this application. A surgical CO 2 laser, operated in single pulse mode (100 milliseconds) at different power settings, was used to ablate different types of cadaveric animal tissues. Tissue samples were then harvested and imaged with synchrotron X-ray phase-contrast and micro-computed tomography to generate stacks of virtual sections of the tissues. Subsequently, Fiji (ImageJ) software was used to locate tissue damage, then to quantify volumes of laser ablation cones and thermal coagulation damage from 3D renderings of tissue image stacks. Visual comparisons of tissue structures in X-ray images with those visible by classic light microscopy histology were made. We demonstrated that micro-computed tomography could be used to rapidly identify areas of surgical laser ablation, vacuolization, carbonization, and thermally coagulated tissue. Quantification and comparison of the ablation crater, which represents the volume of ablated tissue, and the thermal coagulation zone volumes were performed faster than we could by classical histology. We demonstrated that these procedures can be performed on fresh hydrated and non-sectioned plastic embedded tissue. We demonstrated that the application of non-destructive micro-computed tomography to the visualization and analysis of laser induced tissue damage without tissue sectioning is possible. This will improve evaluation of new surgical lasers and their corresponding effect on tissues. Lasers Surg. Med. 48:866-877, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  3. Mitigating intrinsic defects and laser damage using pulsetrain-burst (>100 MHz) ultrafast laser processing

    NASA Astrophysics Data System (ADS)

    McKinney, Luke; Frank, Felix; Graper, David; Dean, Jesse; Forrester, Paul; Rioblanc, Maxence; Nantel, Marc; Marjoribanks, Robin

    2005-09-01

    Ultrafast-laser micromachining has promise as an approach to trimming and 'healing' small laser-produced damage sites in laser-system optics--a common experience in state-of-the-art high-power laser systems. More-conventional approaches currently include mechanical micromachining, chemical modification, and treatment using cw and long-pulse lasers. Laser-optics materials of interest include fused silica, multilayer dielectric stacks for anti-reflection coatings or high-reflectivity mirrors, and inorganic crystals such as KD*P, used for Pockels cells and frequency-doubling. We report on novel efforts using ultrafast-laser pulsetrain-burst processing (microsecond bursts at 133 MHz) to mitigate damage in fused silica, dielectric coatings, and KD*P crystals. We have established the characteristics of pulsetrain-burst micromachining in fused silica, multilayer mirrors, and KD*P, and determined the etch rates and morphology under different conditions of fluence-delivery. From all of these, we have begun to identify new means to optimize the laser-repair of optics defects and damage.

  4. Diagnostics for the detection and evaluation of laser induced damage

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sheehan, L.; Kozlowski, M.; Rainer, F.

    1995-12-31

    The Laser Damage and Conditioning Group at LLNL is evaluating diagnostics which will help make damage testing more efficient and reduce the risk of damage during laser conditioning. The work to date has focused on photoacoustic and scattered light measurements on 1064-nm wavelength HfO{sub 2}/SiO{sub 2} multilayer mirror and polarizer coatings. Both the acoustic and scatter diagnostics have resolved 10 {mu}m diameter damage points in these coatings. Using a scanning stage, the scatter diagnostic can map both intrinsic and laser-induced scatter. Damage threshold measurements obtained using scatter diagnostics compare within experimental error with those measured using 100x Nomarski microscopy. Scattermore » signals measured during laser conditioning can be used to detect damage related to nodular defects.« less

  5. Diagnostics for the detection and evaluation of laser induced damage

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sheehan, L.; Kozlowski, M.; Rainer, F.

    1995-01-03

    The Laser Damage and Conditioning Group at LLNL is evaluating diagnostics which will help make damage testing more efficient and reduce the risk of damage during laser conditioning. The work to date has focused on photoacoustic and scattered light measurements on 1064-nm wavelength HfO{sub 2}/SiO{sub 2} multilayer mirror and polarizer coatings. Both the acoustic and scatter diagnostics have resolved 10 {mu}m diameter damage points in these coatings. Using a scanning stage, the scatter diagnostic can map both intrinsic and laser-induced scatter. Damage threshold measurements obtained using scatter diagnostics compare within experimental error with those measured using 100x Nomarski microscopy. Scattermore » signals measured during laser conditioning can be used to detect damage related to nodular defects.« less

  6. An Investigation of Laser Induced Surface Damage in glass.

    DTIC Science & Technology

    1985-06-01

    ROA-RI60 669 RN INVESTIGATION OF LASER INDUCED SURFACE DAMAG IN In1 1 6lo GLASS (U) NAVAL POSTGRADUATE SCHOOL MONTEREY CA R D UYAK JUN 85IUNCLASSIFIED...ii -0 NAVAL POSTGRADUATE SCHOOL Monterey, California bor OCT THESIS AN INVESTIGATION OF LASER INDUCED SURFACE DAMAGE IN GLASS by )Richard David Uyak ,L...Subtitle) EPORT 6 PERIOD COVERED %An Investigation of Laser Induced Master’s Thesis Surface Damage in Glass June 1985S. PERFORMING ORG. REPORT MUMMER 7

  7. Recruitment of TRF2 to laser-induced DNA damage sites.

    PubMed

    Huda, Nazmul; Abe, Satoshi; Gu, Ling; Mendonca, Marc S; Mohanty, Samarendra; Gilley, David

    2012-09-01

    Several lines of evidence suggest that the telomere-associated protein TRF2 plays critical roles in the DNA damage response. TRF2 is rapidly and transiently phosphorylated by an ATM-dependent pathway in response to DNA damage and this DNA damage-induced phosphoryation is essential for the DNA-PK-dependent pathway of DNA double-strand break repair (DSB). However, the type of DNA damage that induces TRF2 localization to the damage sites, the requirement for DNA damage-induced phosphorylation of TRF2 for its recruitment, as well as the detailed kinetics of TRF2 accumulation at DNA damage sites have not been fully investigated. In order to address these questions, we used an ultrafast femtosecond multiphoton laser and a continuous wave 405-nm single photon laser to induce DNA damage at defined nuclear locations. Our results showed that DNA damage produced by a femtosecond multiphoton laser was sufficient for localization of TRF2 to these DNA damage sites. We also demonstrate that ectopically expressed TRF2 was recruited to DNA lesions created by a 405-nm laser. Our data suggest that ATM and DNA-PKcs kinases are not required for TRF2 localization to DNA damage sites. Furthermore, we found that phosphorylation of TRF2 at residue T188 was not essential for its recruitment to laser-induced DNA damage sites. Thus, we provide further evidence that a protein known to function in telomere maintenance, TRF2, is recruited to sites of DNA damage and plays critical roles in the DNA damage response. Copyright © 2012 Elsevier Inc. All rights reserved.

  8. DNA damage in blood cells exposed to low-level lasers.

    PubMed

    Sergio, Luiz Philippe da Silva; Silva, Ana Paula Almeida da; Amorim, Philipi Freitas; Campos, Vera Maria Araújo; Magalhães, Luis Alexandre Gonçalves; de Paoli, Flavia; de Souza da Fonseca, Adenilson

    2015-04-01

    In regenerative medicine, there are increasing applications of low-level lasers in therapeutic protocols for treatment of diseases in soft and in bone tissues. However, there are doubts about effects on DNA, and an adequate dosimetry could improve the safety of clinical applications of these lasers. This work aimed to evaluate DNA damage in peripheral blood cells of Wistar rats induced by low-level red and infrared lasers at different fluences, powers, and emission modes according to therapeutic protocols. Peripheral blood samples were exposed to lasers and DNA damage was accessed by comet assay. In other experiments, DNA damage was accessed in blood cells by modified comet assay using formamidopyrimidine DNA glycosylase (Fpg) and endonuclease III enzymes. Data show that exposure to low-level red and infrared lasers induce DNA damage depending on fluence, power and emission mode, which are targeted by Fpg and endonuclease III. Oxidative DNA damage should be considered for therapeutic efficacy and patient safety in clinical applications based on low-level red and infrared lasers. © 2015 Wiley Periodicals, Inc.

  9. Laser-induced damage threshold of camera sensors and micro-optoelectromechanical systems

    NASA Astrophysics Data System (ADS)

    Schwarz, Bastian; Ritt, Gunnar; Koerber, Michael; Eberle, Bernd

    2017-03-01

    The continuous development of laser systems toward more compact and efficient devices constitutes an increasing threat to electro-optical imaging sensors, such as complementary metal-oxide-semiconductors (CMOS) and charge-coupled devices. These types of electronic sensors are used in day-to-day life but also in military or civil security applications. In camera systems dedicated to specific tasks, micro-optoelectromechanical systems, such as a digital micromirror device (DMD), are part of the optical setup. In such systems, the DMD can be located at an intermediate focal plane of the optics and it is also susceptible to laser damage. The goal of our work is to enhance the knowledge of damaging effects on such devices exposed to laser light. The experimental setup for the investigation of laser-induced damage is described in detail. As laser sources, both pulsed lasers and continuous-wave (CW)-lasers are used. The laser-induced damage threshold is determined by the single-shot method by increasing the pulse energy from pulse to pulse or in the case of CW-lasers, by increasing the laser power. Furthermore, we investigate the morphology of laser-induced damage patterns and the dependence of the number of destructive device elements on the laser pulse energy or laser power. In addition to the destruction of single pixels, we observe aftereffects, such as persistent dead columns or rows of pixels in the sensor image.

  10. Laser-based structural sensing and surface damage detection

    NASA Astrophysics Data System (ADS)

    Guldur, Burcu

    Damage due to age or accumulated damage from hazards on existing structures poses a worldwide problem. In order to evaluate the current status of aging, deteriorating and damaged structures, it is vital to accurately assess the present conditions. It is possible to capture the in situ condition of structures by using laser scanners that create dense three-dimensional point clouds. This research investigates the use of high resolution three-dimensional terrestrial laser scanners with image capturing abilities as tools to capture geometric range data of complex scenes for structural engineering applications. Laser scanning technology is continuously improving, with commonly available scanners now capturing over 1,000,000 texture-mapped points per second with an accuracy of ~2 mm. However, automatically extracting meaningful information from point clouds remains a challenge, and the current state-of-the-art requires significant user interaction. The first objective of this research is to use widely accepted point cloud processing steps such as registration, feature extraction, segmentation, surface fitting and object detection to divide laser scanner data into meaningful object clusters and then apply several damage detection methods to these clusters. This required establishing a process for extracting important information from raw laser-scanned data sets such as the location, orientation and size of objects in a scanned region, and location of damaged regions on a structure. For this purpose, first a methodology for processing range data to identify objects in a scene is presented and then, once the objects from model library are correctly detected and fitted into the captured point cloud, these fitted objects are compared with the as-is point cloud of the investigated object to locate defects on the structure. The algorithms are demonstrated on synthetic scenes and validated on range data collected from test specimens and test-bed bridges. The second objective of

  11. Subsurface defects of fused silica optics and laser induced damage at 351 nm.

    PubMed

    Hongjie, Liu; Jin, Huang; Fengrui, Wang; Xinda, Zhou; Xin, Ye; Xiaoyan, Zhou; Laixi, Sun; Xiaodong, Jiang; Zhan, Sui; Wanguo, Zheng

    2013-05-20

    Many kinds of subsurface defects are always present together in the subsurface of fused silica optics. It is imperfect that only one kind of defects is isolated to investigate its impact on laser damage. Therefore it is necessary to investigate the impact of subsurface defects on laser induced damage of fused silica optics with a comprehensive vision. In this work, we choose the fused silica samples manufactured by different vendors to characterize subsurface defects and measure laser induced damage. Contamination defects, subsurface damage (SSD), optical-thermal absorption and hardness of fused silica surface are characterized with time-of-flight secondary ion mass spectrometry (TOF-SIMS), fluorescence microscopy, photo-thermal common-path interferometer and fully automatic micro-hardness tester respectively. Laser induced damage threshold and damage density are measured by 351 nm nanosecond pulse laser. The correlations existing between defects and laser induced damage are analyzed. The results show that Cerium element and SSD both have a good correlation with laser-induced damage thresholds and damage density. Research results evaluate process technology of fused silica optics in China at present. Furthermore, the results can provide technique support for improving laser induced damage performance of fused silica.

  12. Development of high damage threshold laser-machined apodizers and gain filters for laser applications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rambo, Patrick; Schwarz, Jens; Kimmel, Mark

    We have developed high damage threshold filters to modify the spatial profile of a high energy laser beam. The filters are formed by laser ablation of a transmissive window. The ablation sites constitute scattering centers which can be filtered in a subsequent spatial filter. Finally, by creating the filters in dielectric materials, we see an increased laser-induced damage threshold from previous filters created using ‘metal on glass’ lithography.

  13. Development of high damage threshold laser-machined apodizers and gain filters for laser applications

    DOE PAGES

    Rambo, Patrick; Schwarz, Jens; Kimmel, Mark; ...

    2016-09-27

    We have developed high damage threshold filters to modify the spatial profile of a high energy laser beam. The filters are formed by laser ablation of a transmissive window. The ablation sites constitute scattering centers which can be filtered in a subsequent spatial filter. Finally, by creating the filters in dielectric materials, we see an increased laser-induced damage threshold from previous filters created using ‘metal on glass’ lithography.

  14. Robust optimization of the laser induced damage threshold of dielectric mirrors for high power lasers.

    PubMed

    Chorel, Marine; Lanternier, Thomas; Lavastre, Éric; Bonod, Nicolas; Bousquet, Bruno; Néauport, Jérôme

    2018-04-30

    We report on a numerical optimization of the laser induced damage threshold of multi-dielectric high reflection mirrors in the sub-picosecond regime. We highlight the interplay between the electric field distribution, refractive index and intrinsic laser induced damage threshold of the materials on the overall laser induced damage threshold (LIDT) of the multilayer. We describe an optimization method of the multilayer that minimizes the field enhancement in high refractive index materials while preserving a near perfect reflectivity. This method yields a significant improvement of the damage resistance since a maximum increase of 40% can be achieved on the overall LIDT of the multilayer.

  15. Characterization of laser induced damage of HR coatings with picosecond pulses

    NASA Astrophysics Data System (ADS)

    Li, Cheng; Zhao, Yuan'an; Cui, Yun; Wang, Yueliang; Peng, Xiaocong; Shan, Chong; Zhu, Meiping; Wang, Jianguo; Shao, Jianda

    2017-11-01

    The effect of protective layer on the picosecond laser-induced damage behaviors of HfO2/SiO2 high-reflective (HR) coatings are explored. Two kinds of 1064nm HR coatings with and without protective layer are deposited by electron beam evaporation. Laser-induced damage tests are conducted with 1064nm, 30ps S-polarized and P-polarized pulses with different angle of incidence (AOI) to make the electric fields intensity in the HR coatings discrepantly. Damage morphology and cross section of damage sites were characterized by scanning electron microscope (SEM) and focused ion beam (FIB), respectively. It is found that SiO2 protective layer have a certain degree of improvement on laser induced damage threshold (LIDT) for every AOIs. The onset damage initiated very near to the Max peak of e-field, after which forms ripple-like pits. The damage morphology presents as layer delamination at high fluence. The Laser damage resistance is correspond with the maximum E-intensity in the coating stacks.

  16. Laser Damage in Thin Film Optical Coatings

    DTIC Science & Technology

    1992-07-01

    10) using E- beam evaporation and laser tests performed to determine the effect of conditioning laser spot size and coating design on improvement in...1.06 pm) consisting of a 15 layer 3 quarter-wave design (HFO2/SiO 2 and ZrO2/SiO 2) were fabricated by E- beam evaporation. Sol-gel processing was used to... designers select laser damage resistant coatings for optical elements to be employed in military systems using lasers or encountering lasers used as

  17. Scalable process for mitigation of laser-damaged potassium dihydrogen phosphate crystal optic surfaces with removal of damaged antireflective coating

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Elhadj, S.; Steele, W. A.; VanBlarcom, D. S.

    Here, we investigate an approach for the recycling of laser-damaged large-aperture deuterated potassium dihydrogen phosphate (DKDP) crystals used for optical switching (KDP) and for frequency conversion (DKDP) in megajoule-class high-power laser systems. The approach consists of micromachining the surface laser damage sites (mitigation), combined with multiple soaks and ultrasonication steps in a coating solvent to remove, synergistically, both the highly adherent machining debris and the laser-damage-affected antireflection coating. We then identify features of the laser-damage-affected coating, such as the “solvent-persistent” coating and the “burned-in” coating, that are difficult to remove by conventional approaches without damaging the surface. We also providemore » a solution to the erosion problem identified in this work when colloidal coatings are processed during ultrasonication. Finally, we provide a proof of principle of the approach by testing the full process that includes laser damage mitigation of DKDP test parts, coat stripping, reapplication of a new antireflective coat, and a laser damage test demonstrating performance up to at least 12 J/cm 2 at UV wavelengths, which is well above current requirements. Our approach ultimately provides a potential path to a scalable recycling loop for the management of optics in large, high-power laser systems that can reduce cost and extend lifetime of highly valuable and difficult to grow large DKDP crystals.« less

  18. Scalable process for mitigation of laser-damaged potassium dihydrogen phosphate crystal optic surfaces with removal of damaged antireflective coating

    DOE PAGES

    Elhadj, S.; Steele, W. A.; VanBlarcom, D. S.; ...

    2017-03-07

    Here, we investigate an approach for the recycling of laser-damaged large-aperture deuterated potassium dihydrogen phosphate (DKDP) crystals used for optical switching (KDP) and for frequency conversion (DKDP) in megajoule-class high-power laser systems. The approach consists of micromachining the surface laser damage sites (mitigation), combined with multiple soaks and ultrasonication steps in a coating solvent to remove, synergistically, both the highly adherent machining debris and the laser-damage-affected antireflection coating. We then identify features of the laser-damage-affected coating, such as the “solvent-persistent” coating and the “burned-in” coating, that are difficult to remove by conventional approaches without damaging the surface. We also providemore » a solution to the erosion problem identified in this work when colloidal coatings are processed during ultrasonication. Finally, we provide a proof of principle of the approach by testing the full process that includes laser damage mitigation of DKDP test parts, coat stripping, reapplication of a new antireflective coat, and a laser damage test demonstrating performance up to at least 12 J/cm 2 at UV wavelengths, which is well above current requirements. Our approach ultimately provides a potential path to a scalable recycling loop for the management of optics in large, high-power laser systems that can reduce cost and extend lifetime of highly valuable and difficult to grow large DKDP crystals.« less

  19. Laser induced damage thresholds and laser safety levels. Do the units of measurement matter?

    NASA Astrophysics Data System (ADS)

    Wood, R. M.

    1998-04-01

    The commonly used units of measurement for laser induced damage are those of peak energy or power density. However, the laser induced damage thresholds, LIDT, of all materials are well known to be absorption, wavelength, spot size and pulse length dependent. As workers using these values become divorced from the theory it becomes increasingly important to use the correct units and to understand the correct scaling factors. This paper summarizes the theory and highlights the danger of using the wrong LIDT units in the context of potentially hazardous materials, laser safety eyewear and laser safety screens.

  20. Catastrophic nanosecond laser induced damage in the bulk of potassium titanyl phosphate crystals

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wagner, Frank R., E-mail: frank.wagner@fresnel.fr; Natoli, Jean-Yves; Akhouayri, Hassan

    2014-06-28

    Due to its high effective nonlinearity and the possibility to produce periodically poled crystals, potassium titanyl phosphate (KTiOPO{sub 4}, KTP) is still one of the economically important nonlinear optical materials. In this overview article, we present a large study on catastrophic nanosecond laser induced damage in this material and the very similar RbTiOPO{sub 4} (RTP). Several different systematic studies are included: multiple pulse laser damage, multi-wavelength laser damage in KTP, damage resistance anisotropy, and variations of the laser damage thresholds for RTP crystals of different qualities. All measurements were carried out in comparable experimental conditions using a 1064 nm Q-switched lasermore » and some were repeated at 532 nm. After summarizing the experimental results, we detail the proposed model for laser damage in this material and discuss the experimental results in this context. According to the model, nanosecond laser damage is caused by light-induced generation of transient laser-damage precursors which subsequently provide free electrons that are heated by the same nanosecond pulse. We also present a stimulated Raman scattering measurement and confront slightly different models to the experimental data. Finally, the physical nature of the transient damage precursors is discussed and similarities and differences to laser damage in other crystals are pointed out.« less

  1. Characterization of laser damage performance of fused silica using photothermal absorption technique

    NASA Astrophysics Data System (ADS)

    Wan, Wen; Shi, Feng; Dai, Yifan; Peng, Xiaoqiang

    2017-06-01

    The subsurface damage and metal impurities have been the main laser damage precursors of fused silica while subjected to high power laser irradiation. Light field enhancement and thermal absorption were used to explain the appearance of damage pits while the laser energy is far smaller than the energy that can reach the intrinsic threshold of fused silica. For fused silica optics manufactured by magnetorheological finishing or advanced mitigation process, no scratch-related damage site occurs can be found on the surface. In this work, we implemented a photothermal absorption technique based on thermal lens method to characterize the subsurface defects of fused silica optics. The pump beam is CW 532 nm wavelength laser. The probe beam is a He-Ne laser. They are collinear and focused through the same objective. When pump beam pass through the sample, optical absorption induces the local temperature rise. The lowest absorptance that we can detect is about the order of magnitude of 0.01 ppm. When pump beam pass through the sample, optical absorption induces the local temperature rise. The photothermal absorption value of fused silica samples range from 0.5 to 10 ppm. The damage densities of the samples were plotted. The damage threshold of samples at 8J/cm2 were gived to show laser damage performance of fused silica.The results show that there is a strong correlation between the thermal absorption and laser damage density. The photothermal absorption technique can be used to predict and evaluate the laser damage performance of fused silica optics.

  2. Low-power-laser therapy used in tendon damage

    NASA Astrophysics Data System (ADS)

    Strupinska, Ewa

    1996-03-01

    The following paper covers evaluation of low-power laser therapy results in chronic Achilles tendon damage and external Epicondylalia (tennis elbow). Fifty patients with Achilles damage (18 women and 32 men, age average 30, 24 plus or minus 10, 39 years) and fifty patients having external Epicondyalgiae (31 women and 19 men, age average 44, 36 plus or minus 10, 88 years) have been examined. The patients were irradiated by semiconductor infrared laser wavelength 904 nm separately or together with helium-neon laser wavelength 632.8 nm. The results of therapy have been based on the patient's interviews and examinations of patients as well as on the Laitinen pain questionnaire. The results prove analgesic effects in usage of low- power laser radiation therapy can be obtained.

  3. EFFECTS OF LASER RADIATION ON MATTER: Laser damage behaviour of titania coatings

    NASA Astrophysics Data System (ADS)

    Skvortsov, L. A.

    2010-01-01

    A model is proposed for the generation of defects responsible for laser damage in thin titania films during repetitive exposure to nanosecond near-IR laser pulses. The model relies on the hypothesis that there is charge transfer between two point defect centres differing in photoionisation cross section, one of which has an adsorptive nature. The model's predictions agree well with the experimentally determined accumulation curve and the temperature dependence of the damage threshold at low temperatures and clarify the role of protective coatings.

  4. Pulsed laser-induced damage of metals at 492 nm.

    PubMed

    Marrs, C D; Faith, W N; Dancy, J H; Porteus, J O

    1982-11-15

    A triaxial flashlamp-pumped dye laser has been used to perform laser damage testing of metal surfaces in the blue-green spectral region. Using LD490 laser dye, the laser produces 0.18-J, 0.5-microsec pulses at 492 nm. The spatial profile of the focused beam is measured in orthogonal directions in the plane of the sample surface. The orthogonal profiles are flat-topped Gaussians with 1/e(2) widths of 270 microm. Multithreshold laser damage test results are presented for polished Mo, diamond-turned high-purity Al alloy, diamond-turned bulk Cu, and diamond-turned electrodeposits of Ag and Au on Cu. Comparisons are made between calculated and experimentally measured slip and melt thresholds.

  5. Neuronal growth cones respond to laser-induced axonal damage

    PubMed Central

    Wu, Tao; Mohanty, Samarendra; Gomez-Godinez, Veronica; Shi, Linda Z.; Liaw, Lih-Huei; Miotke, Jill; Meyer, Ronald L.; Berns, Michael W.

    2012-01-01

    Although it is well known that damage to neurons results in release of substances that inhibit axonal growth, release of chemical signals from damaged axons that attract axon growth cones has not been observed. In this study, a 532 nm 12 ns laser was focused to a diffraction-limited spot to produce site-specific damage to single goldfish axons in vitro. The axons underwent a localized decrease in thickness (‘thinning’) within seconds. Analysis by fluorescence and transmission electron microscopy indicated that there was no gross rupture of the cell membrane. Mitochondrial transport along the axonal cytoskeleton immediately stopped at the damage site, but recovered over several minutes. Within seconds of damage nearby growth cones extended filopodia towards the injury and were often observed to contact the damaged site. Turning of the growth cone towards the injured axon also was observed. Repair of the laser-induced damage was evidenced by recovery of the axon thickness as well as restoration of mitochondrial movement. We describe a new process of growth cone response to damaged axons. This has been possible through the interface of optics (laser subcellular surgery), fluorescence and electron microscopy, and a goldfish retinal ganglion cell culture model. PMID:21831892

  6. Pulsewidth-dependent nature of laser-induced DNA damage in RPE cells

    NASA Astrophysics Data System (ADS)

    Hall, Rebecca M.; Glickman, Randolph D.; Rockwell, Benjamin A.; Kumar, Neeru; Noojin, Gary D.

    2001-07-01

    Ultrashort pulse laser radiation may produce cellular damage through unique mechanisms. Primary cultures of bovine retinal pigment epithelial (RPE) cells were exposed to the out put of a Ti:Sapphire laser producing 30 fs (mode-locked) pulses, 44 amplified fs pulses, or continuous wave exposures at 800 nm. Laser exposures at and below the damage threshold were studied. DNA damage was detected using single cell gel electrophoresis (comet assay). Unexposed (control) cells produced short tails with low tail moments. In contrast, all laser-exposed cells showed some degree of DNA fragmentation, but the size and shape of the resulting comets differed among the various modalities. CW-exposed cells produced generally light and relatively compact tails, suggesting fewer and larger DNA fragments, while mode-locked laser exposures (30 fs pulses) resulted in large and diffuse comets, indicating the DNA was fragmented into many very small pieces. Work is continuing to define the relationship of laser pulsewidth and intensity with the degree of DNA fragmentation. These results suggest that DNA damage may result from multiple mechanisms of laser-cell interaction, including multiphoton absorption.

  7. Combining wet etching and real-time damage event imaging to reveal the most dangerous laser damage initiator in fused silica.

    PubMed

    Hu, Guohang; Zhao, Yuanan; Liu, Xiaofeng; Li, Dawei; Xiao, Qiling; Yi, Kui; Shao, Jianda

    2013-08-01

    A reliable method, combining a wet etch process and real-time damage event imaging during a raster scan laser damage test, has been developed to directly determine the most dangerous precursor inducing low-density laser damage at 355 nm in fused silica. It is revealed that ~16% of laser damage sites were initiated at the place of the scratches, ~49% initiated at the digs, and ~35% initiated at invisible defects. The morphologies of dangerous scratches and digs were compared with those of moderate ones. It is found that local sharp variation at the edge, twist, or inside of a subsurface defect is the most dangerous laser damage precursor.

  8. Small Optics Laser Damage Test Procedure

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wolfe, Justin

    2017-10-19

    This specification defines the requirements and procedure for laser damage testing of coatings and bare surfaces designated for small optics in the National Ignition Facility (NIF) at Lawrence Livermore National Laboratory (LLNL).

  9. Dynamics of laser-induced damage of spherical nanoparticles by high-intensity ultrashort laser pulses

    NASA Astrophysics Data System (ADS)

    Komolov, Vladimir L.; Gruzdev, Vitaly E.; Przhibelskii, Sergey G.; Smirnov, Dmitry S.

    2012-12-01

    Damage of a metal spherical nanoparticle by femtosecond laser pulses is analyzed by splitting the overall process into two steps. The fast step includes electron photoemission from a nanoparticle. It takes place during direct action of a laser pulse and its rate is evaluated as a function of laser and particle parameters by two approaches. Obtained results suggest the formation of significant positive charge of the nanoparticles due to the photoemission. The next step includes ion emission that removes the excessive positive charge and modifies particle structure. It is delayed with respect to the photo-emission and is analyzed by a simple analytical model and modified molecular dynamics. Obtained energy distribution suggests generation of fast ions capable of penetrating into surrounding material and generating defects next to the nanoparticle. The modeling is extended to the case of a nanoparticle on a solid surface to understand the basic mechanism of surface laser damage initiated by nano-contamination. Simulations predict embedding the emitted ions into substrate within a spot with size significantly exceeding the original particle size. We discuss the relation of those effects to the problem of bulk and surface laser-induced damage of optical materials by single and multiple ultrashort laser pulses.

  10. Ultrashort Laser Retinal Damage Threshold Mechanisms

    DTIC Science & Technology

    2010-01-15

    epithelium . Below one nanosecond both stress-confinement in melanosomes and self-focusing reduce the threshold for damage as measured in corneal radiant... epithelium (RPE). Below 1 ns, both stress confinement in melanosomes and self-focusing reduce the threshold for damage as measured in corneal radiant...collimated laser light is focused to a very small spot on the retina. The retinal pigment epithelium (RPE) contains melanosomes, which are the primary

  11. Growth behavior of laser-induced damage on fused silica optics under UV, ns laser irradiation.

    PubMed

    Negres, Raluca A; Norton, Mary A; Cross, David A; Carr, Christopher W

    2010-09-13

    The growth behavior of laser-induced damage sites is affected by a large number of laser parameters as well as site morphology. Here we investigate the effects of pulse duration on the growth rate of damage sites located on the exit surface of fused silica optics. Results demonstrate a significant dependence of the growth parameters on laser pulse duration at 351 nm from 1 ns to 15 ns, including the observation of a dominant exponential versus linear, multiple-shot growth behavior for long and short pulses, respectively. These salient behaviors are tied to the damage morphology and suggest a shift in the fundamental growth mechanisms for pulses in the 1-5 ns range.

  12. Advanced Mitigation Process (AMP) for Improving Laser Damage Threshold of Fused Silica Optics

    NASA Astrophysics Data System (ADS)

    Ye, Xin; Huang, Jin; Liu, Hongjie; Geng, Feng; Sun, Laixi; Jiang, Xiaodong; Wu, Weidong; Qiao, Liang; Zu, Xiaotao; Zheng, Wanguo

    2016-08-01

    The laser damage precursors in subsurface of fused silica (e.g. photosensitive impurities, scratches and redeposited silica compounds) were mitigated by mineral acid leaching and HF etching with multi-frequency ultrasonic agitation, respectively. The comparison of scratches morphology after static etching and high-frequency ultrasonic agitation etching was devoted in our case. And comparison of laser induce damage resistance of scratched and non-scratched fused silica surfaces after HF etching with high-frequency ultrasonic agitation were also investigated in this study. The global laser induce damage resistance was increased significantly after the laser damage precursors were mitigated in this case. The redeposition of reaction produce was avoided by involving multi-frequency ultrasonic and chemical leaching process. These methods made the increase of laser damage threshold more stable. In addition, there is no scratch related damage initiations found on the samples which were treated by Advanced Mitigation Process.

  13. Advanced Mitigation Process (AMP) for Improving Laser Damage Threshold of Fused Silica Optics

    PubMed Central

    Ye, Xin; Huang, Jin; Liu, Hongjie; Geng, Feng; Sun, Laixi; Jiang, Xiaodong; Wu, Weidong; Qiao, Liang; Zu, Xiaotao; Zheng, Wanguo

    2016-01-01

    The laser damage precursors in subsurface of fused silica (e.g. photosensitive impurities, scratches and redeposited silica compounds) were mitigated by mineral acid leaching and HF etching with multi-frequency ultrasonic agitation, respectively. The comparison of scratches morphology after static etching and high-frequency ultrasonic agitation etching was devoted in our case. And comparison of laser induce damage resistance of scratched and non-scratched fused silica surfaces after HF etching with high-frequency ultrasonic agitation were also investigated in this study. The global laser induce damage resistance was increased significantly after the laser damage precursors were mitigated in this case. The redeposition of reaction produce was avoided by involving multi-frequency ultrasonic and chemical leaching process. These methods made the increase of laser damage threshold more stable. In addition, there is no scratch related damage initiations found on the samples which were treated by Advanced Mitigation Process. PMID:27484188

  14. Characteristics and mechanism of laser-induced surface damage initiated by metal contaminants

    NASA Astrophysics Data System (ADS)

    Shi, Shuang; Sun, Mingying; Shi, Shuaixu; Li, Zhaoyan; Zhang, Ya-nan; Liu, Zhigang

    2015-08-01

    In high power laser facility, contaminants on optics surfaces reduce damage resistance of optical elements and then decrease their lifetime. By damage test experiments, laser damage induced by typical metal particles such as stainless steel 304 is studied. Optics samples with metal particles of different sizes on surfaces are prepared artificially based on the file and sieve. Damage test is implemented in air using a 1-on-1 mode. Results show that damage morphology and mechanism caused by particulate contamination on the incident and exit surfaces are quite different. Contaminants on the incident surface absorb laser energy and generate high temperature plasma during laser irradiation which can ablate optical surface. Metal particles melt and then the molten nano-particles redeposit around the initial particles. Central region of the damaged area bears the same outline as the initial particle because of the shielding effect. However, particles on the exit surface absorb a mass of energy, generate plasma and splash lots of smaller particles, only a few of them redeposit at the particle coverage area on the exit surface. Most of the laser energy is deposited at the interface of the metal particle and the sample surface, and thus damage size on the exit surface is larger than that on the incident surface. The areas covered by the metal particle are strongly damaged. And the damage sites are more serious than that on the incident surface. Besides damage phenomenon also depends on coating and substrate materials.

  15. A statistical study of the relationship between surface quality and laser induced damage

    NASA Astrophysics Data System (ADS)

    Turner, Trey; Turchette, Quentin; Martin, Alex R.

    2012-11-01

    Laser induced damage of optical components is a concern in many applications in the commercial, scientific and military market sectors. Numerous component manufacturers supply "high laser damage threshold" (HLDT) optics to meet the needs of this market, and consumers pay a premium price for these products. While there's no question that HLDT optics are manufactured to more rigorous standards (and are therefore inherently more expensive) than conventional products, it is not clear how this added expense translates directly into better performance. This is because the standard methods for evaluating laser damage, and the underlying assumptions about the validity of traditional laser damage testing, are flawed. In particular, the surface and coating defects that generally lead to laser damage (in many laserparameter regimes of interest) are widely distributed over the component surface with large spaces in between them. As a result, laser damage testing typically doesn't include enough of these defects to achieve the sample sizes necessary to make its results statistically meaningful. The result is a poor correlation between defect characteristics and damage events. This paper establishes specifically why this is the case, and provides some indication of what might be done to remedy the problem.

  16. Laser damage threshold of gelatin and a copper phthalocyanine doped gelatin optical limiter

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brant, M.C.; McLean, D.G.; Sutherland, R.L.

    1996-12-31

    The authors demonstrate optical limiting in a unique guest-host system which uses neither the typical liquid or solid host. Instead, they dope a gelatin gel host with a water soluble Copper (II) phthalocyaninetetrasulfonic acid, tetrasodium salt (CuPcTs). They report on the gelatin`s viscoelasticity, laser damage threshold, and self healing of this damage. The viscoelastic gelatin has mechanical properties quite different than a liquid or solid. The authors` laser measurements demonstrate that the single shot damage threshold of the undoped gelatin host increases with decreasing gelatin concentration. The gelatin also has a much higher laser damage threshold than a stiff acrylic.more » Unlike brittle solids, the soft gelatin self heals from laser induced damage. Optical limiting test also show the utility of a gelatin host doped with CuPcTs. The CuPcTs/gelatin matrix is not damaged at incident laser energies 5 times the single shot damage threshold of the gelatin host. However, at this high laser energy the CuPcTs is photo bleached at the beam waist. The authors repair photo bleached sites by annealing the CuPcTs/gelatin matrix.« less

  17. Predicting threshold and location of laser damage on optical surfaces

    DOEpatents

    Siekhaus, Wigbert

    1987-01-01

    An apparatus useful in the prediction of the damage threshold of various optical devices, the location of weak spots on such devices and the location, identification, and elimination of optical surface impurities comprising, a focused and pulsed laser, an photo electric detector/imaging means, and a timer. The weak spots emit photoelectrons when subjected to laser intensities that are less than the intensity actually required to produce the damage. The weak spots may be eliminated by sustained exposure to the laser beam.

  18. Plasma spectrum peak extraction algorithm of laser film damage

    NASA Astrophysics Data System (ADS)

    Zhao, Dan; Su, Jun-hong; Xu, Jun-qi

    2012-10-01

    The plasma spectrometry is an emerging method to distinguish the thin-film laser damage. Laser irradiation film surface occurrence of flash, using the spectrometer receives the flash spectrum, extracting the spectral peak, and by means of the spectra of the thin-film materials and the atmosphere has determine the difference, as a standard to determine the film damage. Plasma spectrometry can eliminate the miscarriage of justice which caused by atmospheric flashes, and distinguish high accuracy. Plasma spectra extraction algorithm is the key technology of Plasma spectrometry. Firstly, data de noising and smoothing filter is introduced in this paper, and then during the peak is detecting, the data packet is proposed, and this method can increase the stability and accuracy of the spectral peak recognition. Such algorithm makes simultaneous measurement of Plasma spectrometry to detect thin film laser damage, and greatly improves work efficiency.

  19. Laser-induced damage of coatings on Yb:YAG crystals at cryogenic condition

    NASA Astrophysics Data System (ADS)

    Wang, He; Zhang, Weili; Chen, Shunli; Zhu, Meiping; He, Hongbo; Fan, Zhengxiu

    2011-12-01

    As large amounts of heat need to be dissipated during laser operation, some diode pumped solid state lasers (DPSSL), especially Yb:YAG laser, operate at cryogenic condition. This work investigated the laser induced damage of coatings (high-reflective and anti-reflective coatings) on Yb:YAG crystals at cryogenic temperature and room temperature. The results show that the damage threshold of coatings at cryogenic temperature is lower than the one at room temperature. Field-emission scanning electron microscopy (FESEM), optical profiler, step profiler and Atomic force microscope (AFM) were used to obtain the damage morphology, size and depth. Taking alteration of physical parameters, microstructure of coatings and the environmental pollution into consideration, we analyzed the key factor of lowering the coating damage threshold at cryogenic conditions. The results are important to understand the mechanisms leading to damage at cryogenic condition.

  20. Laser-induced damage threshold of camera sensors and micro-opto-electro-mechanical systems

    NASA Astrophysics Data System (ADS)

    Schwarz, Bastian; Ritt, Gunnar; Körber, Michael; Eberle, Bernd

    2016-10-01

    The continuous development of laser systems towards more compact and efficient devices constitutes an increasing threat to electro-optical imaging sensors such as complementary metal-oxide-semiconductors (CMOS) and charge-coupled devices (CCD). These types of electronic sensors are used in day-to-day life but also in military or civil security applications. In camera systems dedicated to specific tasks, also micro-opto-electro-mechanical systems (MOEMS) like a digital micromirror device (DMD) are part of the optical setup. In such systems, the DMD can be located at an intermediate focal plane of the optics and it is also susceptible to laser damage. The goal of our work is to enhance the knowledge of damaging effects on such devices exposed to laser light. The experimental setup for the investigation of laser-induced damage is described in detail. As laser sources both pulsed lasers and continuous-wave (CW) lasers are used. The laser-induced damage threshold (LIDT) is determined by the single-shot method by increasing the pulse energy from pulse to pulse or in the case of CW-lasers, by increasing the laser power. Furthermore, we investigate the morphology of laser-induced damage patterns and the dependence of the number of destructed device elements on the laser pulse energy or laser power. In addition to the destruction of single pixels, we observe aftereffects like persisting dead columns or rows of pixels in the sensor image.

  1. Damage resistant optics for a megajoule solid state laser

    NASA Astrophysics Data System (ADS)

    Campbell, Jack H.; Rainer, Frank; Kozlowski, Mark R.; Wolfe, C. Robert; Thomas, Ian M.; Milanovich, Fred P.

    1991-06-01

    Research on Inertial Confinement Fusion (ICF) has progressed rapidly in the past several years. As a consequence LLNL is developing plans to upgrade the current 120 kJ solid state (Nd3-phosphate glass) Nova laser to a 1 . 5 to 2 megajoule system with the goal of achieving fusion ignition. The design of the planned Nova Upgrade is briefly discussed. Because of recent improvements in the damage resistance of optical materials it is now technically and economically feasible to build a megajoule-class solid state laser. Specifically the damage threshold of Nd3- doped phosphate laser glass muliilayer dielectric coatings and non-linear optical crystals (e. g. KDP) have been dramatically improved. These materials now meet the fluence requirements for a 1. 5-2 MJ Nd3-glass laser operating at 1054 and 351 nm and at a pulse length of 3 ns. The recent improvements in damage thresholds are reviewed threshold data at both 1064 and 355 nm and the measured pulse length scaling are presented. 1.

  2. Reduction of thermal damage in photodynamic therapy by laser irradiation techniques.

    PubMed

    Lim, Hyun Soo

    2012-12-01

    General application of continuous-wave (CW) laser irradiation modes in photodynamic therapy can cause thermal damage to normal tissues in addition to tumors. A new photodynamic laser therapy system using a pulse irradiation mode was optimized to reduce nonspecific thermal damage. In in vitro tissue specimens, tissue energy deposition rates were measured in three irradiation modes, CW, pulse, and burst-pulse. In addition, methods were tested for reducing variations in laser output and specific wavelength shifts using a thermoelectric cooler and thermistor. The average temperature elevation per 10 J/cm2 was 0.27°C, 0.09°C, and 0.08°C using the three methods, respectively, in pig muscle tissue. Variations in laser output were controlled within ± 0.2%, and specific wavelength shift was limited to ± 3 nm. Thus, optimization of a photodynamic laser system was achieved using a new pulse irradiation mode and controlled laser output to reduce potential thermal damage during conventional CW-based photodynamic therapy.

  3. Fabrication of mitigation pits for improving laser damage resistance in dielectric mirrors by femtosecond laser machining

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wolfe, Justin E.; Qiu, S. Roger; Stolz, Christopher J.

    2011-03-20

    Femtosecond laser machining is used to create mitigation pits to stabilize nanosecond laser-induced damage in multilayer dielectric mirror coatings on BK7 substrates. In this paper, we characterize features and the artifacts associated with mitigation pits and further investigate the impact of pulse energy and pulse duration on pit quality and damage resistance. Our results show that these mitigation features can double the fluence-handling capability of large-aperture optical multilayer mirror coatings and further demonstrate that femtosecond laser macromachining is a promising means for fabricating mitigation geometry in multilayer coatings to increase mirror performance under high-power laser irradiation.

  4. Predicting threshold and location of laser damage on optical surfaces

    DOEpatents

    Siekhaus, W.

    1985-02-04

    Disclosed is an apparatus useful in the prediction of the damage threshold of various optical devices, the location of weak spots on such devices and the location, identification, and elimination of optical surface impurities. The apparatus comprises a focused and pulsed laser, a photo electric detector/imaging means, and a timer. The weak spots emit photoelectrons when subjected to laser intensities that are less than the intensity actually required to produce the damage. The weak spots may be eliminated by sustained exposure to the laser beam.

  5. Effect of annealing on the laser induced damage of polished and CO2 laser-processed fused silica surfaces

    NASA Astrophysics Data System (ADS)

    Doualle, T.; Gallais, L.; Cormont, P.; Donval, T.; Lamaignère, L.; Rullier, J. L.

    2016-06-01

    We investigate the effect of different heat treatments on the laser-induced damage probabilities of fused silica samples. Isothermal annealing in a furnace is applied, with different temperatures in the range 700-1100 °C and 12 h annealing time, to super-polished fused silica samples. The surface flatness and laser damage probabilities at 3 ns, 351 nm are measured before and after the different annealing procedures. We have found a significant improvement of the initial laser damage probabilities of the silica surface after annealing at 1050 °C for 12 h. A similar study has been conducted on CO2 laser-processed sites on the surface of the samples. Before and after annealing, we have studied the morphology of the sites, the evolution of residual stress, and the laser-induced damage threshold measured at 351 nm, 3 ns. In this case, we observe that the laser damage resistance of the laser created craters can reach the damage level of the bare fused silica surface after the annealing process, with a complete stress relieve. The obtained results are then compared to the case of local annealing process by CO2 laser irradiation during 1 s, and we found similar improvements in both cases. The different results obtained in the study are compared to numerical simulations made with a thermo-mechanical model based on finite-element method that allows the simulation of the isothermal or the local annealing process, the evolution of stress and fictive temperature. The simulation results were found to be very consistent with experimental observations for the stresses evolution after annealing and estimation of the heat affected area during laser-processing based on the density dependence with fictive temperature. Following this work, the temperature for local annealing should reach 1330-1470 °C for an optimized reduction of damage probability and be below the threshold for material removal, whereas furnace annealing should be kept below the annealing point to avoid sample

  6. Improved laser damage threshold for chalcogenide glasses through surface microstructuring

    NASA Astrophysics Data System (ADS)

    Florea, Catalin; Sanghera, Jasbinder; Busse, Lynda; Shaw, Brandon; Aggarwal, Ishwar

    2011-03-01

    We demonstrate improved laser damage threshold of chalcogenide glasses with microstructured surfaces as compared to chalcogenide glasses provided with traditional antireflection coatings. The surface microstructuring is used to reduce Fresnel losses over large bandwidths in As2S3 glasses and fibers. The treated surfaces show almost a factor of two of improvement in the laser damage threshold when compared with untreated surfaces.

  7. Infrared skin damage thresholds from 1319-nm continuous-wave laser exposures

    NASA Astrophysics Data System (ADS)

    Oliver, Jeffrey W.; Vincelette, Rebecca; Noojin, Gary D.; Clark, Clifton D.; Harbert, Corey A.; Schuster, Kurt J.; Shingledecker, Aurora D.; Kumru, Semih S.; Maughan, Justin; Kitzis, Naomi; Buffington, Gavin D.; Stolarski, David J.; Thomas, Robert J.

    2013-12-01

    A series of experiments were conducted in vivo using Yucatan miniature pigs (Sus scrofa domestica) to determine thermal damage thresholds to the skin from 1319-nm continuous-wave Nd:YAG laser irradiation. Experiments employed exposure durations of 0.25, 1.0, 2.5, and 10 s and beam diameters of ˜0.6 and 1 cm. Thermal imagery data provided a time-dependent surface temperature response from the laser. A damage endpoint of fifty percent probability of a minimally visible effect was used to determine threshold for damage at 1 and 24 h postexposure. Predicted thermal response and damage thresholds are compared with a numerical model of optical-thermal interaction. Resultant trends with respect to exposure duration and beam diameter are compared with current standardized exposure limits for laser safety. Mathematical modeling agreed well with experimental data, predicting that though laser safety standards are sufficient for exposures <10 s, they may become less safe for very long exposures.

  8. Detector Damage at X-Ray Free-Electron Laser Sources

    NASA Astrophysics Data System (ADS)

    Blaj, G.; Carini, G.; Carron, S.; Haller, G.; Hart, P.; Hasi, J.; Herrmann, S.; Kenney, C.; Segal, J.; Stan, C. A.; Tomada, A.

    2016-06-01

    Free-electron lasers (FELs) opened a new window on imaging the motion of atoms and molecules. At SLAC, FEL experiments are performed at LCLS using 120 Hz pulses with 1012 to 1013 photons in 10 fs (billions of times brighter than at the most powerful synchrotrons). Concurrently, users and staff operate under high pressure due to flexible and often rapidly changing setups and low tolerance for system malfunction. This extreme detection environment raises unique challenges, from obvious to surprising, and leads to treating detectors as consumables. We discuss in detail the detector damage mechanisms observed in 7 years of operation at LCLS, together with the corresponding damage mitigation strategies and their effectiveness. Main types of damage mechanisms already identified include: (1) x-ray radiation damage (from “catastrophic” to “classical”), (2) direct and indirect damage caused by optical lasers, (3) sample induced damage, (4) vacuum related damage, (5) high-pressure environment. In total, 19 damage mechanisms have been identified. We also present general strategies for reducing damage risk or minimizing the impact of detector damage on the science program. These include availability of replacement parts and skilled operators and also careful planning, incident investigation resulting in updated designs, procedures and operator training.

  9. A high-throughput comparative characterization of laser-induced soft tissue damage using 3D digital microscopy.

    PubMed

    Das, Debobrato; Reed, Stephanie; Klokkevold, Perry R; Wu, Benjamin M

    2013-02-01

    3D digital microscopy was used to develop a rapid alternative approach to quantify the effects of specific laser parameters on soft tissue ablation and charring in vitro without the use of conventional tissue processing techniques. Two diode lasers operating at 810 and 980 nm wavelengths were used to ablate three tissue types (bovine liver, turkey breast, and bovine muscle) at varying laser power (0.3, 1.0, and 2.0 W) and velocities (1-50 mm/s). Spectrophotometric analyses were performed on each tissue to determine tissue-specific absorption coefficients and were considered in creating wavelength-dependent energy attenuation models to evaluate minimum heat of tissue ablations. 3D surface contour profiles characterizing tissue damage revealed that ablation depth and tissue charring increased with laser power and decreased with lateral velocity independent of wavelength and tissue type. While bovine liver ablation and charring were statistically higher at 810 than 980 nm (p < 0.05), turkey breast and bovine muscle ablated and charred more at 980 than 810 nm (p < 0.05). Spectrophotometric analysis revealed that bovine liver tissue had a greater tissue-specific absorption coefficient at 810 than 980 nm, while turkey breast and bovine muscle had a larger absorption coefficient at 980 nm (p < 0.05). This rapid 3D microscopic analysis of robot-driven laser ablation yielded highly reproducible data that supported well-defined trends related to laser-tissue interactions and enabled high throughput characterization of many laser-tissue permutations. Since 3D microscopy quantifies entire lesions without altering the tissue specimens, conventional and immunohistologic techniques can be used, if desired, to further interrogate specific sections of the digitized lesions.

  10. Laser-Induced Damage Threshold and Certification Procedures for Optical Materials

    NASA Technical Reports Server (NTRS)

    1997-01-01

    This document provides instructions for performing laser-induced-damage-threshold tests and pass-fail certification tests on optical materials used in pulsed-laser systems. The optical materials to which these procedures apply include coated and uncoated optical substrates, laser crystals, Q-switches, polarizers, and other optical components employed in pulsed-laser systems.

  11. High-Resolution In Vivo Imaging of Regimes of Laser Damage to the Primate Retina

    PubMed Central

    Pocock, Ginger M.; Oliver, Jeffrey W.; Specht, Charles S.; Estep, J. Scot; Noojin, Gary D.; Schuster, Kurt; Rockwell, Benjamin A.

    2014-01-01

    Purpose. To investigate fundamental mechanisms of regimes of laser induced damage to the retina and the morphological changes associated with the damage response. Methods. Varying grades of photothermal, photochemical, and photomechanical retinal laser damage were produced in eyes of eight cynomolgus monkeys. An adaptive optics confocal scanning laser ophthalmoscope and spectral domain optical coherence tomographer were combined to simultaneously collect complementary in vivo images of retinal laser damage during and following exposure. Baseline color fundus photography was performed to complement high-resolution imaging. Monkeys were perfused with 10% buffered formalin and eyes were enucleated for histological analysis. Results. Laser energies for visible retinal damage in this study were consistent with previously reported damage thresholds. Lesions were identified in OCT images that were not visible in direct ophthalmoscopic examination or fundus photos. Unique diagnostic characteristics, specific to each damage regime, were identified and associated with shape and localization of lesions to specific retinal layers. Previously undocumented retinal healing response to blue continuous wave laser exposure was recorded through a novel experimental methodology. Conclusion. This study revealed increased sensitivity of lesion detection and improved specificity to the laser of origin utilizing high-resolution imaging when compared to traditional ophthalmic imaging techniques in the retina. PMID:24891943

  12. 355-nm, nanosecond laser mirror thin film damage competition

    NASA Astrophysics Data System (ADS)

    Negres, Raluca A.; Stolz, Christopher J.; Thomas, Michael D.; Caputo, Mark

    2017-11-01

    This competition aimed to survey state-of-the-art UV high reflectors. The requirements of the coatings are a minimum reflection of 99.5% at 45 degrees incidence angle for P-polarized light at 355-nm. The choice of coating materials, design, and deposition method were left to the participants. Laser damage testing was performed at a single testing facility using the raster scan method with a 5-ns pulse length laser system operating at 10 Hz in a single longitudinal mode. A double blind test assured sample and submitter anonymity. In addition to the laser damage resistance results, details of the deposition processes, cleaning method, coating materials and layer count are also shared.

  13. Damage Resistant Optical Glasses for High Power Lasers: A Continuing Glass Science and Technology Challenge

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Campbell, J H

    2002-08-28

    A major challenge in the development of optical glasses for high-power lasers is reducing or eliminating laser-induced damage to the interior (bulk) and the polished surface of the glass. Bulk laser damage in glass generally originates from inclusions. With the development of novel glass melting and forming processes it is now possible to make both fused silica and a suit of meta-phosphate laser glasses in large sizes ({approx}>0.5-lm diameter), free of inclusions and with high optical homogeneity ({approx} 10{sup -6}). Considerable attention also has been focused on improving the laser damage resistance to polished optical glass surfaces. Studies have shownmore » that laser-induced damage to surfaces grows exponentially with the number of shots when illuminated with nano-second pulses at 351-nm above a given fluence threshold. A new approach for reducing and eliminating laser-induced surface damage relies on a series of post-polishing treatment steps. This damage improvement method is briefly reviewed.« less

  14. Non-destructive evaluation of UV pulse laser-induced damage performance of fused silica optics.

    PubMed

    Huang, Jin; Wang, Fengrui; Liu, Hongjie; Geng, Feng; Jiang, Xiaodong; Sun, Laixi; Ye, Xin; Li, Qingzhi; Wu, Weidong; Zheng, Wanguo; Sun, Dunlu

    2017-11-24

    The surface laser damage performance of fused silica optics is related to the distribution of surface defects. In this study, we used chemical etching assisted by ultrasound and magnetorheological finishing to modify defect distribution in a fused silica surface, resulting in fused silica samples with different laser damage performance. Non-destructive test methods such as UV laser-induced fluorescence imaging and photo-thermal deflection were used to characterize the surface defects that contribute to the absorption of UV laser radiation. Our results indicate that the two methods can quantitatively distinguish differences in the distribution of absorptive defects in fused silica samples subjected to different post-processing steps. The percentage of fluorescence defects and the weak absorption coefficient were strongly related to the damage threshold and damage density of fused silica optics, as confirmed by the correlation curves built from statistical analysis of experimental data. The results show that non-destructive evaluation methods such as laser-induced fluorescence and photo-thermal absorption can be effectively applied to estimate the damage performance of fused silica optics at 351 nm pulse laser radiation. This indirect evaluation method is effective for laser damage performance assessment of fused silica optics prior to utilization.

  15. Statistical study of single and multiple pulse laser-induced damage in glasses.

    PubMed

    Gallais, L; Natoli, J; Amra, C

    2002-12-16

    Single and multiple pulse laser damage studies are performed in Suprasil silica and BK-7 borosilicate glasses. Experiments are made in the bulk of materials at 1.064microm with nanosecond pulses, using an accurate and reliable measurement system. By means of a statistical study on laser damage probabilities, we demonstrate that the same nano-precursors could be involved in the multiple shot and single shot damage process. A damage mechanism with two stages is then proposed to explain the results. Firstly, a pre-damage process, corresponding to material changes at a microscopic level, leads the precursor to a state that can induce a one-pulse damage. And secondly a final damage occurs, with a mechanism identical to the single shot case. For each material, a law is found to predict the precursor life-time. We can then deduce the long term life of optical elements in high-power laser systems submitted to multipulse irradiation.

  16. Laser damage helps the eavesdropper in quantum cryptography.

    PubMed

    Bugge, Audun Nystad; Sauge, Sebastien; Ghazali, Aina Mardhiyah M; Skaar, Johannes; Lydersen, Lars; Makarov, Vadim

    2014-02-21

    We propose a class of attacks on quantum key distribution (QKD) systems where an eavesdropper actively engineers new loopholes by using damaging laser illumination to permanently change properties of system components. This can turn a perfect QKD system into a completely insecure system. A proof-of-principle experiment performed on an avalanche photodiode-based detector shows that laser damage can be used to create loopholes. After ∼1  W illumination, the detectors' dark count rate reduces 2-5 times, permanently improving single-photon counting performance. After ∼1.5  W, the detectors switch permanently into the linear photodetection mode and become completely insecure for QKD applications.

  17. Retinal damage from a Q-switched YAG laser.

    PubMed

    Jampol, L M; Goldberg, M F; Jednock, N

    1983-09-01

    A 42-year-old woman with sickle cell anemia and proliferative retinopathy underwent neodymium-YAG laser therapy for a taut posterior hyaloid membrane causing peripapillary and peripheral traction detachment of the retina. Vitrectomy was not done because the patient required anticoagulation. A Q-switched YAG laser was capable of cutting holes in the taut membrane, but treatment 2 to 3 mm from the retina resulted in microperforation of a retinal vein and focal areas of damage to the retinal pigment epithelium. The damage to the retinal pigment epithelium was not immediately apparent, and ophthalmoscopically visible lesions were seen only when the patient was reexamined 48 hours later.

  18. Influence of subsurface defects on damage performance of fused silica in ultraviolet laser

    NASA Astrophysics Data System (ADS)

    Huang, Jin; Zhou, Xinda; Liu, Hongjie; Wang, Fengrui; Jiang, Xiaodong; Wu, Weidong; Tang, Yongjian; Zheng, Wanguo

    2013-02-01

    In ultraviolet pulse laser, damage performance of fused silica optics is directly dependent on the absorptive impurities and scratches in subsurface, which are induced by mechanical polishing. In the research about influence of subsurface defects on damage performance, a series of fused silica surfaces with various impurity concentrations and scratch structures were created by hydrofluoric (HF) acid solution etching. Time of Flight secondary ion mass spectrometry and scanning probe microprobe revealed that with increasing etching depth, impurity concentrations in subsurface layers are decreased, the scratch structures become smoother and the diameter:depth ratio is increased. Damage performance test with 355-nm pulse laser showed that when 600 nm subsurface thickness is removed by HF acid etching, laser-induced damage threshold of fused silica is raised by 40 percent and damage density is decreased by over one order of magnitude. Laser weak absorption was tested to explain the cause of impurity elements impacting damage performance, field enhancement caused by change of scratch structures was calculated by finite difference time domain simulation, and the calculated results are in accord with the damage test results.

  19. 355-nm, nanosecond laser mirror thin film damage competition

    DOE PAGES

    Negres, Raluca A.; Stolz, Christopher J.; Thomas, Michael D.; ...

    2017-11-23

    Here, this competition aimed to survey state-of-the-art UV high reflectors. The requirements of the coatings are a minimum reflection of 99.5% at 45 degrees incidence angle for P-polarized light at 355-nm. The choice of coating materials, design, and deposition method were left to the participants. Laser damage testing was performed at a single testing facility using the raster scan method with a 5-ns pulse length laser system operating at 10 Hz in a single longitudinal mode. A double blind test assured sample and submitter anonymity. Finally, in addition to the laser damage resistance results, details of the deposition processes, cleaningmore » method, coating materials and layer count are also shared.« less

  20. Creation of backdoors in quantum communications via laser damage

    NASA Astrophysics Data System (ADS)

    Makarov, Vadim; Bourgoin, Jean-Philippe; Chaiwongkhot, Poompong; Gagné, Mathieu; Jennewein, Thomas; Kaiser, Sarah; Kashyap, Raman; Legré, Matthieu; Minshull, Carter; Sajeed, Shihan

    2016-09-01

    Practical quantum communication (QC) protocols are assumed to be secure provided implemented devices are properly characterized and all known side channels are closed. We show that this is not always true. We demonstrate a laser-damage attack capable of modifying device behavior on demand. We test it on two practical QC systems for key distribution and coin tossing, and show that newly created deviations lead to side channels. This reveals that laser damage is a potential security risk to existing QC systems, and necessitates their testing to guarantee security.

  1. Damage resistant optics for a mega-joule solid-state laser

    NASA Astrophysics Data System (ADS)

    Campbell, J. H.; Rainer, F.; Kozlowski, M. R.; Wolfe, C. R.; Thomas, I.; Milanovich, F.

    1990-12-01

    Research on Inertial Confinement Fusion (ICF) has progressed rapidly in the past several years. As a consequence, LLNL is developing plans to upgrade the current 120 kJ solid state (Nd3+ phosphate glass) Nova laser to a 1.5 to 2 megajoule system with the goal of achieving fusion ignition. The design of the planned Nova Upgrade is briefly discussed. Because of recent improvements in the damage resistance of optical materials it is now technically and economically feasible to build a megajoule-class solid state laser. Specifically, the damage threshold of Nd(+3)-doped phosphate laser glass, multilayer dielectric coatings, and non-linear optical crystals (e.g., KDP) have been dramatically improved. These materials now meet the fluence requirements for a 1.5 to 2 MJ Nd(+3)-glass laser operating at 1054 and 351 nm and at a pulse length of 3 ns. The recent improvements in damage thresholds are reviewed; threshold data at both 1064 and 355 nm and the measured pulse length scaling are presented.

  2. Damage Detection in Rotorcraft Composite Structures Using Thermography and Laser-Based Ultrasound

    NASA Technical Reports Server (NTRS)

    Anastasi, Robert F.; Zalameda, Joseph N.; Madaras, Eric I.

    2004-01-01

    New rotorcraft structural composite designs incorporate lower structural weight, reduced manufacturing complexity, and improved threat protection. These new structural concepts require nondestructive evaluation inspection technologies that can potentially be field-portable and able to inspect complex geometries for damage or structural defects. Two candidate technologies were considered: Thermography and Laser-Based Ultrasound (Laser UT). Thermography and Laser UT have the advantage of being non-contact inspection methods, with Thermography being a full-field imaging method and Laser UT a point scanning technique. These techniques were used to inspect composite samples that contained both embedded flaws and impact damage of various size and shape. Results showed that the inspection techniques were able to detect both embedded and impact damage with varying degrees of success.

  3. Thermal Model of Laser-Induced Eye Damage

    DTIC Science & Technology

    1974-10-08

    Identify by. block ntber) Ocular Damage Laser Effect3 Thermal Model Temperature Rise Prediction Retinal, Corneal, Lenticular Damage 20. ABSTR ACT (CoIfn...routine available to predict retinal or lenticular beam characteristics based on beam de- scripton at the cornea and distance of the last beam waist 5...used are selected for minimal aberrations of the astigmatic kind and that coma is negligible because of nearly axial "illumination. Secondly, the thermal

  4. Laser damage threshold measurements of microstructure-based high reflectors

    NASA Astrophysics Data System (ADS)

    Hobbs, Douglas S.

    2008-10-01

    In 2007, the pulsed laser induced damage threshold (LIDT) of anti-reflecting (AR) microstructures built in fused silica and glass was shown to be up to three times greater than the LIDT of single-layer thin-film AR coatings, and at least five times greater than multiple-layer thin-film AR coatings. This result suggested that microstructure-based wavelength selective mirrors might also exhibit high LIDT. Efficient light reflection over a narrow spectral range can be produced by an array of sub-wavelength sized surface relief microstructures built in a waveguide configuration. Such surface structure resonant (SSR) filters typically achieve a reflectivity exceeding 99% over a 1-10nm range about the filter center wavelength, making SSR filters useful as laser high reflectors (HR). SSR laser mirrors consist of microstructures that are first etched in the surface of fused silica and borosilicate glass windows and subsequently coated with a thin layer of a non-absorbing high refractive index dielectric material such as tantalum pent-oxide or zinc sulfide. Results of an initial investigation into the LIDT of single layer SSR laser mirrors operating at 532nm, 1064nm and 1573nm are described along with data from SEM analysis of the microstructures, and spectral reflection measurements. None of the twelve samples tested exhibited damage thresholds above 3 J/cm2 when illuminated at the resonant wavelength, indicating that the simple single layer, first order design will need further development to be suitable for high power laser applications. Samples of SSR high reflectors entered in the Thin Film Damage Competition also exhibited low damage thresholds of less than 1 J/cm2 for the ZnS coated SSR, and just over 4 J/cm2 for the Ta2O5 coated SSR.

  5. Particle damage sources for fused silica optics and their mitigation on high energy laser systems.

    PubMed

    Bude, J; Carr, C W; Miller, P E; Parham, T; Whitman, P; Monticelli, M; Raman, R; Cross, D; Welday, B; Ravizza, F; Suratwala, T; Davis, J; Fischer, M; Hawley, R; Lee, H; Matthews, M; Norton, M; Nostrand, M; VanBlarcom, D; Sommer, S

    2017-05-15

    High energy laser systems are ultimately limited by laser-induced damage to their critical components. This is especially true of damage to critical fused silica optics, which grows rapidly upon exposure to additional laser pulses. Much progress has been made in eliminating damage precursors in as-processed fused silica optics (the advanced mitigation process, AMP3), and very high damage resistance has been demonstrated in laboratory studies. However, the full potential of these improvements has not yet been realized in actual laser systems. In this work, we explore the importance of additional damage sources-in particular, particle contamination-for fused silica optics fielded in a high-performance laser environment, the National Ignition Facility (NIF) laser system. We demonstrate that the most dangerous sources of particle contamination in a system-level environment are laser-driven particle sources. In the specific case of the NIF laser, we have identified the two important particle sources which account for nearly all the damage observed on AMP3 optics during full laser operation and present mitigations for these particle sources. Finally, with the elimination of these laser-driven particle sources, we demonstrate essentially damage free operation of AMP3 fused silica for ten large optics (a total of 12,000 cm 2 of beam area) for shots from 8.6 J/cm 2 to 9.5 J/cm 2 of 351 nm light (3 ns Gaussian pulse shapes). Potentially many other pulsed high energy laser systems have similar particle sources, and given the insight provided by this study, their identification and elimination should be possible. The mitigations demonstrated here are currently being employed for all large UV silica optics on the National Ignition Facility.

  6. Laser induced damage in optical materials: tenth ASTM symposium.

    PubMed

    Glass, A J; Guenther, A H

    1979-07-01

    The tenth annual Symposium on Optical Materials for High Power Lasers (Boulder Damage Symposium) was held at the National Bureau of Standards in Boulder, Colorado, 12-14 September 1978. The symposium was held under the auspices of ASTM Committee F-1, Subcommittee on Laser Standards, with the joint sponsorship of NBS, the Defense Advanced Research Project Agency, the Department of Energy, and the Office of Naval Research. About 175 scientists attended, including representatives of the United Kingdom, France, Canada, Japan, West Germany, and the Soviet Union. The symposium was divided into sessions concerning the measurement of absorption characteristics, bulk material properties, mirrors and surfaces, thin film damage, coating materials and design, and breakdown phenomena. As in previous years, the emphasis of the papers presented was directed toward new frontiers and new developments. Particular emphasis was given to materials for use from 10.6 microm to the UV region. Highlights included surface characterization, thin film-substrate boundaries, and advances in fundamental laser-matter threshold interactions and mechanisms. The scaling of damage thresholds with pulse duration, focal area, and wavelength was also discussed. In commemoration of the tenth symposium in this series, a number of comprehensive review papers were presented to assess the state of the art in various facets of laser induced damage in optical materials. Alexander J. Glass of Lawrence Livermore Laboratory and Arthur H. Guenther of the Air Force Weapons Laboratory were co-chairpersons. The eleventh annual symposium is scheduled for 30-31 October 1979 at the National Bureau of Standards, Boulder, Colorado.

  7. Alternative approach for cavitation damage study utilizing repetitive laser pulses

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ren, Fei; Wang, Jy-An John; Wang, Hong

    2010-01-01

    Cavitation is a common phenomenon in fluid systems that can lead to dramatic degradation of solid materials surface in contact with the cavitating media. Study of cavitation damage has great significance in many engineering fields. Current techniques for cavitation damage study either require large scale equipments or tend to introduce damages from other mechanisms. In this project, we utilized the cavitation phenomenon induced by laser optical breakdown and developed a prototype apparatus for cavitation damage study. In our approach, cavitation was generated by the repetitive pressure waves induced by high-power laser pulses. As proof of principal study, stainless steel andmore » aluminum samples were tested using the novel apparatus. Surface characterization via scanning electron microscopy revealed damages such as indentation and surface pitting, which were similar to those reported in literature using other state-of-the-art techniques. These preliminary results demonstrated the new device was capable of generating cavitation damages and could be used as an alternative method for cavitation damage study.« less

  8. R-on-1 automatic mapping: A new tool for laser damage testing

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hue, J.; Garrec, P.; Dijon, J.

    1996-12-31

    Laser damage threshold measurement is statistical in nature. For a commercial qualification or for a user, the threshold determined by the weakest point is a satisfactory characterization. When a new coating is designed, threshold mapping is very useful. It enables the technology to be improved and followed more accurately. Different statistical parameters such as the minimum, maximum, average, and standard deviation of the damage threshold as well as spatial parameters such as the threshold uniformity of the coating can be determined. Therefore, in order to achieve a mapping, all the tested sites should give data. This is the major interestmore » of the R-on-1 test in spite of the fact that the laser damage threshold obtained by this method may be different from the 1-on-1 test (smaller or greater). Moreover, on the damage laser test facility, the beam size is smaller (diameters of a few hundred micrometers) than the characteristic sizes of the components in use (diameters of several centimeters up to one meter). Hence, a laser damage threshold mapping appears very interesting, especially for applications linked to large optical components like the Megajoule project or the National Ignition Facility (N.I.F). On the test bench used, damage detection with a Nomarski microscope and scattered light measurement are almost equivalent. Therefore, it becomes possible to automatically detect on line the first defects induced by YAG irradiation. Scattered light mappings and laser damage threshold mappings can therefore be achieved using a X-Y automatic stage (where the test sample is located). The major difficulties due to the automatic capabilities are shown. These characterizations are illustrated at 355 nm. The numerous experiments performed show different kinds of scattering curves, which are discussed in relation with the damage mechanisms.« less

  9. Effects of wet etch processing on laser-induced damage of fused silica surfaces

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Battersby, C.L.; Kozlowski, M.R.; Sheehan, L.M.

    1998-12-22

    Laser-induced damage of transparent fused silica optical components by 355 nm illumination occurs primarily at surface defects produced during the grinding and polishing processes. These defects can either be surface defects or sub-surface damage.Wet etch processing in a buffered hydrogen fluoride (HF) solution has been examined as a tool for characterizing such defects. A study was conducted to understand the effects of etch depth on the damage threshold of fused silica substrates. The study used a 355 nm, 7.5 ns, 10 Hz Nd:YAG laser to damage test fused silica optics through various wet etch processing steps. Inspection of the surfacemore » quality was performed with Nomarski microscopy and Total Internal Reflection Microscopy. The damage test data and inspection results were correlated with polishing process specifics. The results show that a wet etch exposes subsurface damage while maintaining or improving the laser damage performance. The benefits of a wet etch must be evaluated for each polishing process.« less

  10. Laser-induced damage of intrinsic and extrinsic defects by picosecond pulses on multilayer dielectric coatings for petawatt-class lasers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Negres, Raluca A.; Carr, Christopher W.; Laurence, Ted A.

    2016-08-01

    Here, we describe a damage testing system and its use in investigating laser-induced optical damage initiated by both intrinsic and extrinsic precursors on multilayer dielectric coatings suitable for use in high-energy, large-aperture petawatt-class lasers. We employ small-area damage test methodologies to evaluate the intrinsic damage resistance of various coatings as a function of deposition methods and coating materials under simulated use conditions. In addition, we demonstrate that damage initiation by raster scanning at lower fluences and growth threshold testing are required to probe the density of extrinsic defects, which will limit large-aperture optics performance.

  11. Few-cycle pulse laser induced damage threshold determination of ultra-broadband optics.

    PubMed

    Kafka, Kyle R P; Talisa, Noah; Tempea, Gabriel; Austin, Drake R; Neacsu, Catalin; Chowdhury, Enam A

    2016-12-12

    A systematic study of few-cycle pulse laser induced damage threshold (LIDT) determination was performed for commercially-available ultra-broadband optics, (i.e. chirped mirrors, silver mirrors, beamsplitters, etc.) in vacuum and in air, for single and multi-pulse regime (S-on-1). Multi-pulse damage morphology at fluences below the single-pulse LIDT was studied in order to investigate the mechanisms leading to the onset of damage. Stark morphological contrast was observed between multi-pulse damage sites formed in air versus those in vacuum. One effect of vacuum testing compared to air included suppression of laser-induced periodic surface structures (LIPSS) formation, possibly influenced by a reduced presence of damage debris. Another effect of vacuum was occasional lowering of LIDT, which appears to be due to the stress-strain performance of the coating design during laser irradiation and under the external stress of vacuum ambience. A fused silica substrate is also examined, and a non-LIPSS nanostructuring is observed on the surface. Possible mechanisms are discussed.

  12. Laser-induced bulk damage of silica glass at 355nm and 266nm

    NASA Astrophysics Data System (ADS)

    Kashiwagi, R.; Aramomi, S.

    2016-12-01

    Laser processing machines using Nd:YAG 3rd harmonic wave (355 nm) and 4th harmonic wave (266 nm) have been developed and put into practical use lately. Due to this, optical elements with high laser durability to 355 nm and 266 nm are required. Silica glass is the optical element which has high UV transmission and high laser durability. Laser-induced surface damage of the silica glass has been studied in detail, but we hardly have the significant knowledge of laserinduced bulk damage. This knowledge is required in order to evaluate the silica glass itself. That is because cracks and scratches on the surface give rise to a higher possibility of damage. Therefore, we studied the laser durability of a variety of the silica glass samples by 1-on-1 and S-on-1 laser-induced bulk damage threshold (LIDT) at 355 nm and 266 nm. In this study, we gained knowledge in three areas about bulk damage to the silica glass. First, the LIDT became lower as shot counts increased. Second, the LIDT decreased as the hydroxyl content in the silica glass increased. Last, the LIDT became higher as the hydrogen concentration in the silica glass increased. Under the UV irradiation, impurities are generated and the silica glass absorbs more light. Therefore, the LIDT decreased as shot counts increased. Also, the hydroxyl in particular generates more impurities, so damage easily occurs. On the other hand, the hydrogen reacts with impurities and absorption is suppressed. Based on these results, we can improve laser durability at 355 nm and 266 nm by reducing the hydroxyl content and increasing the hydrogen concentration in the silica glass.

  13. Laser damage of HR, AR-coatings, monolayers and bare surfaces at 1064 nm

    NASA Technical Reports Server (NTRS)

    Garnov, S. V.; Klimentov, S. M.; Said, A. A.; Soileau, M. J.

    1993-01-01

    Laser induced damage thresholds and morphologies were investigated in a variety of uncoated and coated surfaces, including monolayers and multi-layers of different chemical compositions. Both antireflective (AR) and highly reflective (HR) were tested. Testing was done at 1064 nm with 25 picosecond and 8 nanosecond YAG/Nd laser single pulses. Spot diameter in the experiments varied from 0.09 to 0.22 mm. The laser damage measurement procedure consisted of 1-on-1 (single laser pulse in the selected site) and N-on-1 experiments including repeated irradiation by pulses of the same fluence and subsequently raised from pulse to pulse fluence until damage occurred. The highest picosecond damage thresholds of commercially available coatings averaged 12 - 14 J/sq cm, 50 percent less than thresholds obtained in bare fused silica. Some coatings and bare surfaces revealed a palpable preconditioning effect (an increase in threshold of 1.2 to 1.8 times). Picosecond and nanosecond data were compared to draw conclusions about pulse width dependence. An attempt was made to classify damage morphologies according to the type of coating, class of irradiating, and damage level.

  14. High-laser-damage-threshold HfO2/SiO2 mirrors manufactured by sputtering process

    NASA Astrophysics Data System (ADS)

    Fornier, Anne; Bernardino, D.; Lam, Odile; Neauport, Jerome; Dufour, Francois; Schmitt, Bernard R.; Mackowski, Jean-Marie

    1999-07-01

    A major preoccupation for the design of the LMJ laser is the mirrors laser damage threshold. SAGEM SA, in collaboration with the CEA, has conducted a study in order to improve the laser induced damage threshold under operational conditions.

  15. Optoacoustic monitoring of cutting efficiency and thermal damage during laser ablation.

    PubMed

    Bay, Erwin; Douplik, Alexandre; Razansky, Daniel

    2014-05-01

    Successful laser surgery is characterized by a precise cut and effective hemostasis with minimal collateral thermal damage to the adjacent tissues. Consequently, the surgeon needs to control several parameters, such as power, pulse repetition rate, and velocity of movements. In this study we propose utilizing optoacoustics for providing the necessary real-time feedback of cutting efficiency and collateral thermal damage. Laser ablation was performed on a bovine meat slab using a Q-switched Nd-YAG laser (532 nm, 4 kHz, 18 W). Due to the short pulse duration of 7.6 ns, the same laser has also been used for generation of optoacoustic signals. Both the shockwaves, generated due to tissue removal, as well as the normal optoacoustic responses from the surrounding tissue were detected using a single broadband piezoelectric transducer. It has been observed that the rapid reduction in the shockwave amplitude occurs as more material is being removed, indicating decrease in cutting efficiency, whereas gradual decrease in the optoacoustic signal likely corresponds to coagulation around the ablation crater. Further heating of the surrounding tissue leads to carbonization accompanied by a significant shift in the optoacoustic spectra. Our results hold promise for real-time monitoring of cutting efficiency and collateral thermal damage during laser surgery. In practice, this could eventually facilitate development of automatic cut-off mechanisms that will guarantee an optimal tradeoff between cutting and heating while avoiding severe thermal damage to the surrounding tissues.

  16. Understanding the Femtosecond Laser-Solid Interaction Near and Beyond the Material Damage Threshold

    DTIC Science & Technology

    2016-05-23

    study of the fundamentals of femtosecond laser damage as a function of various parameters, laser wavelength, pulsewidth, pulse number, experimental ... experimental observation without any free parameters. The brand new FSD Lab constructed under the BRI grant in the Physics Research Building at the Ohio... studied across a range of band-gaps for s- and p-polarized light and it is found that conventional theoretical prediction on laser damage threshold

  17. Reduction of damage initiation density in fused silica optics via UV laser conditioning

    DOEpatents

    Peterson, John E.; Maricle, Stephen M.; Brusasco, Raymond M.; Penetrante, Bernardino M.

    2004-03-16

    The present invention provides a method for reducing the density of sites on the surface of fused silica optics that are prone to the initiation of laser-induced damage, resulting in optics which have far fewer catastrophic defects and are better capable of resisting optical deterioration upon exposure for a long period of time to a high-power laser beam having a wavelength of about 360 nm or less. The initiation of laser-induced damage is reduced by conditioning the optic at low fluences below levels that normally lead to catastrophic growth of damage. When the optic is then irradiated at its high fluence design limit, the concentration of catastrophic damage sites that form on the surface of the optic is greatly reduced.

  18. Laser-Induced Thermal-Mechanical Damage Characteristics of Cleartran Multispectral Zinc Sulfide with Temperature-Dependent Properties

    NASA Astrophysics Data System (ADS)

    Peng, Yajing; Jiang, Yanxue; Yang, Yanqiang

    2015-01-01

    Laser-induced thermal-mechanical damage characteristics of window materials are the focus problems in laser weapon and anti-radiation reinforcement technology. Thermal-mechanical effects and damage characteristics are investigated for cleartran multispectral zinc sulfide (ZnS) thin film window materials irradiated by continuous laser using three-dimensional (3D) thermal-mechanical model. Some temperature-dependent parameters are introduced into the model. The temporal-spatial distributions of temperature and thermal stress are exhibited. The damage mechanism is analyzed. The influences of temperature effect of material parameters and laser intensity on the development of thermal stress and the damage characteristics are examined. The results show, the von Mises equivalent stress along the thickness direction is fluctuant, which originates from the transformation of principal stresses from compressive stress to tensile stress with the increase of depth from irradiated surface. The damage originates from the thermal stress but not the melting. The thermal stress is increased and the damage is accelerated by introducing the temperature effect of parameters or the increasing laser intensity.

  19. Laser induced damage in optical materials: ninth ASTM symposium.

    PubMed

    Glass, A J; Guenther, A H

    1978-08-01

    The Ninth Annual Symposium on Optical Materials for High Power Lasers (Boulder Damage Symposium) was held at the National Bureau of Standards in Boulder, Colorado, 4-6 October 1977. The symposium was under the auspices of ASTM Committee F-1, Subcommittee on Laser Standards, with the joint sponsorship of NBS, the Defense Advanced Research Project Agency, the Department of Energy (formerly ERDA), and the Office of Naval Research. About 185 scientists attended, including representatives of the United Kingdom, France, Canada, Australia, Union of South Africa, and the Soviet Union. The Symposium was divided into sessions concerning Laser Windows and Materials, Mirrors and Surfaces, Thin Films, Laser Glass and Glass Lasers, and Fundamental Mechanisms. As in previous years, the emphasis of the papers was directed toward new frontiers and new developments. Particular emphasis was given to materials for use from 10.6 microm to the uv region. Highlights included surface characterization, thin film-substrate boundaries, and advances in fundamental laser-matter threshold interactions and mechanisms. The scaling of damage thresholds with pulse duration, focal area, and wavelength were also discussed. Alexander J. Glass of Lawrence Livermore Laboratory and Arthur H. Guenther of the Air Force Weapons Laboratory were co-chairpersons. The Tenth Annual Symposium is scheduled for 12-14 September 1978 at the National Bureau of Standards, Boulder, Colorado.

  20. Mitigation of laser damage on National Ignition Facility optics in volume production

    NASA Astrophysics Data System (ADS)

    Folta, James; Nostrand, Mike; Honig, John; Wong, Nan; Ravizza, Frank; Geraghty, Paul; Taranowski, Mike; Johnson, Gary; Larkin, Glenn; Ravizza, Doug; Peterson, John; Welday, Brian; Wegner, Paul

    2013-12-01

    The National Ignition Facility has recently achieved the milestone of delivering over 1.8 MJ and 500 TW of 351 nm laser energy and power on target, which required average fluences up to 9 J/cm2 (3 ns equivalent) in the final optics system. Commercial fused silica laser-grade UV optics typically have a maximum operating threshold of 5 J/cm2. We have developed an optics recycling process which enables NIF to operate above the laser damage initiation and growth thresholds. We previously reported a method to mitigate laser damage with laser ablation of the damage site to leave benign cone shaped pits. We have since developed a production facility with four mitigation systems capable of performing the mitigation protocols on full-sized (430 mm) optics in volume production. We have successfully repaired over 700 NIF optics (unique serial numbers), some of which have been recycled as many as 11 times. We describe the mitigation systems, the optics recycle loop process, and optics recycle production data.

  1. Neuroprotective vaccination with copolymer-1 decreases laser-induced retinal damage

    NASA Astrophysics Data System (ADS)

    Belokopytov, Mark; Dubinsky, Galina; Belkin, Michael; Rosner, Mordechai

    2003-06-01

    The retinal damage induced by laser photocoagulation increases manifold by the secondary degeneration process whereby tissues adjacent to the primary lesion are destroyed. The neuroprotective effect of immunization by glatiramer acetate (Copolymer-1, Cop-1) in adjuvant was previously demonstrated in models of retina, optic nerve, brain, and spinal cord lesions. The present study tested the neuroprotective ability of Cop-1 to reduce the spread of laser-induced retinal damage. Standard argon laser lesions were created in 72 DA pigmented rats divided into four groups: two Cop-1 treated groups (animals treated seven days before or immediately after the laser session) and two control groups treated respectively by saline or the effective but toxic neuroprotective compound MK-801. The histological and morphological evaluations of the lesions 3, 20, and 60 days after the injury revealed significant reduction in photoreceptor loss of the retinas of the pre-immunized animals. Cop-1 given after the laser injury did not prevent cell loss significantly, while the neuroprotective effect of MK-801 was observed only on the third day after the laser injury. The results show that pre-immunization with Cop-1 is neuroprotective in unmyelinated (gray matter) neural tissue such as the retina. This approach may be of clinical significance in ameliorating laser-induced retinal injuries in humans.

  2. Cell damage evaluation of mammalian cells in cell manipulation by amplified femtosecond ytterbium laser

    NASA Astrophysics Data System (ADS)

    Hong, Z.-Y.; Iino, T.; Hagihara, H.; Maeno, T.; Okano, K.; Yasukuni, R.; Hosokawa, Y.

    2018-03-01

    A micrometer-scale explosion with cavitation bubble generation is induced by focusing a femtosecond laser in an aqueous solution. We have proposed to apply the explosion as an impulsive force to manipulate mammalian cells especially in microfluidic chip. Herein, we employed an amplified femtosecond ytterbium laser as an excitation source for the explosion and evaluated cell damage in the manipulation process to clarify the application potential. The damage of C2C12 myoblast cell prepared as a representative mammalian cell was investigated as a function of distance between cell and laser focal point. Although the cell received strong damage on the direct laser irradiation condition, the damage sharply decreased with increasing distance. Since the threshold distance, above which the cell had no damage, was consistent with radius of the cavitation bubble, impact of the cavitation bubble would be a critical factor for the cell damage. The damage had strong nonlinearity in the pulse energy dependence. On the other hand, cell position shift by the impact of the cavitation bubble was almost proportional to the pulse energy. In balance between the cell viability and the cell position shift, we elucidated controllability of the cell manipulation in microfluidic chip.

  3. Ablation velocity and thermal damage of myocardial tissue using a CO2 laser for transmyocardial laser revascularization

    NASA Astrophysics Data System (ADS)

    Sachinopoulou, Anna; Beek, Johan F.; van Leeuwen, Ton G. J. M.; Beek, W. J.

    1999-02-01

    Transmyocardial Laser Revascularization (TMLR) is a new experimental method for relief of angina pectoris in patients with severe coronary artery disease. TMLR aims at revascularizing chronic hibernating myocardium by creating transmural channels. One of the working mechanism hypotheses is that the endocardial side of the channels remains open, enabling perfusion of the hibernating myocardium directly from the left ventricle. Although the working mechanism of TMLR is still unknown (perfusion through patent channels, induction of angiogenesis, relief of angina through destruction of sympatic innervation, others?), first clinical studies are successful. Currently, the Heart LaserTM and other CO2 lasers, XeCl Excimer laser and Ho:YAG laser are under investigation for TMLR. The initial attempts of TMR with needles were soon replaced by laser induced channels. Efforts were focused on developing a CO2 laser that could penetrate a beating heart during its relaxation phase. Later, the position of the beam could be fixed in the myocardial wall using lasers with fiber delivery systems and perforation was achieved within multiple cycles. Various researchers reported on both patent and non-patent channels after TMLR. Our belief is that the extent of laser induced thermal damage is one of the factors that determine the clinical outcome and the extent of angiogenesis (and, possibly, the patency of the channel). The purpose of this study is to present a simple theoretical model to predict the extent of thermal damage around a transmyocardial channel. In vitro experiments were performed on myocardial bovine tissue and damage was assessed. The results were used to determine the final parameters of the approximating theoretical equation. To evaluate our results, we compared our results to in vitro data using the Heart LaserTM from the literature. Ablation velocities were also measured and the results were compared to ablation velocity calculations using a model described by Ostegar

  4. Non-damaging laser therapy of the macula: Titration algorithm and tissue response

    NASA Astrophysics Data System (ADS)

    Palanker, Daniel; Lavinsky, Daniel; Dalal, Roopa; Huie, Philip

    2014-02-01

    Retinal photocoagulation typically results in permanent scarring and scotomata, which limit its applicability to the macula, preclude treatments in the fovea, and restrict the retreatments. Non-damaging approaches to laser therapy have been tested in the past, but the lack of reliable titration and slow treatment paradigms limited their clinical use. We developed and tested a titration algorithm for sub-visible and non-damaging treatments of the retina with pulses sufficiently short to be used with pattern laser scanning. The algorithm based on Arrhenius model of tissue damage optimizes the power and duration for every energy level, relative to the threshold of lesion visibility established during titration (and defined as 100%). Experiments with pigmented rabbits established that lesions in the 50-75% energy range were invisible ophthalmoscopically, but detectable with Fluorescein Angiography and OCT, while at 30% energy there was only very minor damage to the RPE, which recovered within a few days. Patients with Diabetic Macular Edema (DME) and Central Serous Retinopathy (CSR) have been treated over the edematous areas at 30% energy, using 200μm spots with 0.25 diameter spacing. No signs of laser damage have been detected with any imaging modality. In CSR patients, subretinal fluid resolved within 45 days. In DME patients the edema decreased by approximately 150μm over 60 days. After 3-4 months some patients presented with recurrence of edema, and they responded well to retreatment with the same parameters, without any clinically visible damage. This pilot data indicates a possibility of effective and repeatable macular laser therapy below the tissue damage threshold.

  5. Atmospheric effects on laser eye safety and damage to instrumentation

    NASA Astrophysics Data System (ADS)

    Zilberman, Arkadi; Kopeika, Natan S.

    2017-10-01

    Electro-optical sensors as well as unprotected human eyes are extremely sensitive to laser radiation and can be permanently damaged from direct or reflected beams. Laser detector/eye hazard depends on the interaction between the laser beam and the media in which it traverses. The environmental conditions including terrain features, atmospheric particulate and water content, and turbulence, may alter the laser's effect on the detector/eye. It is possible to estimate the performance of an electro-optical system as long as the atmospheric propagation of the laser beam can be adequately modeled. More recent experiments and modeling of atmospheric optics phenomena such as inner scale effect, aperture averaging, atmospheric attenuation in NIR-SWIR, and Cn2 modeling justify an update of previous eye/detector safety modeling. In the present work, the influence of the atmospheric channel on laser safety for personnel and instrumentation is shown on the basis of theoretical and experimental data of laser irradiance statistics for different atmospheric conditions. A method for evaluating the probability of damage and hazard distances associated with the use of laser systems in a turbulent atmosphere operating in the visible and NIR-SWIR portions of the electromagnetic spectrum is presented. It can be used as a performance prediction model for directed energy engagement of ground-based or air-based systems.

  6. New method for measuring the laser-induced damage threshold of optical thin film

    NASA Astrophysics Data System (ADS)

    Su, Jun-hong; Wang, Hong; Xi, Ying-xue

    2012-10-01

    The laser-induced damage threshold (LIDT) of thin film means that the thin film can withstand a maximum intensity of laser radiation. The film will be damaged when the irradiation under high laser intensity is greater than the value of LIDT. In this paper, an experimental platform with measurement operator interfaces and control procedures in the VB circumstance is built according to ISO11254-1. In order to obtain more accurate results than that with manual measurement, in the software system, a hardware device can be controlled by control widget on the operator interfaces. According to the sample characteristic, critical parameters of the LIDT measurement system such as spot diameter, damage threshold region, and critical damage pixel number are set up on the man-machine conversation interface, which could realize intelligent measurements of the LIDT. According to experimental data, the LIDT is obtained by fitting damage curve automatically.

  7. Effects of substrate on the femtosecond laser-induced damage properties of gold films

    NASA Astrophysics Data System (ADS)

    Huang, Haopeng; Wang, Leilei; Kong, Fanyu; Xia, Zhilin; Jin, Yunxia; Xu, Jiao; Chen, Junming; Cui, Yun; Shao, Jianda

    2018-07-01

    In this work, gold films on two different types of substrates were fabricated by electron beam (e-beam) evaporation, and the femtosecond laser-induced damage properties were evaluated. The first sample was gold film deposited on fused silica, whereas the second was gold deposited on photoresist. 1-on-1 damage tests were implemented by an 800 ± 30 nm laser with pulse duration of 30 fs. Different damage thresholds and morphologies were obtained for the two samples. The damage threshold of the gold film on fused silica was 0.64 J/cm2, with the typical damage morphology of thermal ablation and melting; the damage threshold of the gold film on photoresist was 0.30 J/cm2, with the typical damage morphology of blisters or peeling off. In order to better understand the impact of the substrate on the properties of the whole sample, the normalized electric field intensity, temperature, and thermal stress distributions were calculated. The adhesion between the gold film and substrate were measured and the experimental results well agreed with the theoretical analysis. The results indicate that gold films deposited onto grating-structured fused silica will have more powerful laser damage resistance performance.

  8. Quantifying the Influence of Lightning Strike Pressure Loading on Composite Specimen Damage

    NASA Astrophysics Data System (ADS)

    Foster, P.; Abdelal, G.; Murphy, A.

    2018-04-01

    Experimental work has shown that a component of lightning strike damage is caused by a mechanical loading. As the profile of the pressure loading is unknown a number of authors propose different pressure loads, varying in form, application area and magnitude. The objective of this paper is to investigate the potential contribution of pressure loading to composite specimen damage. This is achieved through a simulation study using an established modelling approach for composite damage prediction. The study examines the proposed shockwave loads from the literature. The simulation results are compared with measured test specimen damage examining the form and scale of damage. The results for the first time quantify the significance of pressure loading, demonstrating that although a pressure load can cause damage consistent with that measured experimentally, it has a negligible contribution to the overall scale of damage. Moreover the requirements for a pressure to create the damage behaviours typically witnessed in testing requires that the pressure load be within a very precise window of magnitude and loading area.

  9. Heat damage-free laser-microjet cutting achieves highest die fracture strength

    NASA Astrophysics Data System (ADS)

    Perrottet, Delphine; Housh, Roy; Richerzhagen, Bernold; Manley, John

    2005-04-01

    Unlike conventional laser-based technologies, the water jet guided laser does not generate heat damage and contamination is also very low. The negligible heat-affected zone is one reason why die fracture strength is higher than with sawing. This paper first presents the water jet guided laser technology and then explains how it differs from conventional dry laser cutting. Finally, it presents the results obtained by three recent studies conducted to determine die fracture strength after Laser-Microjet cutting.

  10. Wavelength dependence of femtosecond laser-induced damage threshold of optical materials

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gallais, L., E-mail: laurent.gallais@fresnel.fr; Douti, D.-B.; Commandré, M.

    2015-06-14

    An experimental and numerical study of the laser-induced damage of the surface of optical material in the femtosecond regime is presented. The objective of this work is to investigate the different processes involved as a function of the ratio of photon to bandgap energies and compare the results to models based on nonlinear ionization processes. Experimentally, the laser-induced damage threshold of optical materials has been studied in a range of wavelengths from 1030 nm (1.2 eV) to 310 nm (4 eV) with pulse durations of 100 fs with the use of an optical parametric amplifier system. Semi-conductors and dielectrics materials, in bulk or thinmore » film forms, in a range of bandgap from 1 to 10 eV have been tested in order to investigate the scaling of the femtosecond laser damage threshold with the bandgap and photon energy. A model based on the Keldysh photo-ionization theory and the description of impact ionization by a multiple-rate-equation system is used to explain the dependence of laser-breakdown with the photon energy. The calculated damage fluence threshold is found to be consistent with experimental results. From these results, the relative importance of the ionization processes can be derived depending on material properties and irradiation conditions. Moreover, the observed damage morphologies can be described within the framework of the model by taking into account the dynamics of energy deposition with one dimensional propagation simulations in the excited material and thermodynamical considerations.« less

  11. Carcinogenic damage to deoxyribonucleic acid is induced by near-infrared laser pulses in multiphoton microscopy via combination of two- and three-photon absorption

    NASA Astrophysics Data System (ADS)

    Nadiarnykh, Oleg; Thomas, Giju; Van Voskuilen, Johan; Sterenborg, Henricus J. C. M.; Gerritsen, Hans C.

    2012-11-01

    Nonlinear optical imaging modalities (multiphoton excited fluorescence, second and third harmonic generation) applied in vivo are increasingly promising for clinical diagnostics and the monitoring of cancer and other disorders, as they can probe tissue with high diffraction-limited resolution at near-infrared (IR) wavelengths. However, high peak intensity of femtosecond laser pulses required for two-photon processes causes formation of cyclobutane-pyrimidine-dimers (CPDs) in cellular deoxyribonucleic acid (DNA) similar to damage from exposure to solar ultraviolet (UV) light. Inaccurate repair of subsequent mutations increases the risk of carcinogenesis. In this study, we investigate CPD damage that results in Chinese hamster ovary cells in vitro from imaging them with two-photon excited autofluorescence. The CPD levels are quantified by immunofluorescent staining. We further evaluate the extent of CPD damage with respect to varied wavelength, pulse width at focal plane, and pixel dwell time as compared with more pronounced damage from UV sources. While CPD damage has been expected to result from three-photon absorption, our results reveal that CPDs are induced by competing two- and three-photon absorption processes, where the former accesses UVA absorption band. This finding is independently confirmed by nonlinear dependencies of damage on laser power, wavelength, and pulse width.

  12. Laser Damage and Effects Bibliography. Part 1. Journal Literature through 1982

    DTIC Science & Technology

    1984-06-15

    F.; BROST , George ; SCHMID, Ansgar; KELLY, P. J. "The Role of Laser-Induced Primary Defect Formation in Optical Breakdown of NaCl" IEEE J. Quantum...Induced Damage in Optical Materials: 1980, Nat. Bur. Stands. (U.S.), Spec. ubl. 620 (Oct 81) 403-405 BRAUNLICH, Peter F.; BROST , George ; SCHMID...James; RITTER, George J. "Laser-Induced Damage in Copper Crystals" Appl. Phys. Lett. 9 (1 Oct 66) 272-273 PERESSINI, E. H. "Field Emission from Atoms in

  13. Generation of Scratches and Their Effects on Laser Damage Performance of Silica Glass

    PubMed Central

    Li, Yaguo; Ye, Hui; Yuan, Zhigang; Liu, Zhichao; Zheng, Yi; Zhang, Zhe; Zhao, Shijie; Wang, Jian; Xu, Qiao

    2016-01-01

    Scratches are deleterious to precision optics because they can obscure and modulate incident laser light, which will increase the probability of damage to optical components. We here imitated the generation of brittle and ductile scratches during polishing process and endeavored to find out the possible influence of scratches on laser induced damage. Brittle scratches can be induced by spiking large sized abrasives and small abrasives may only generate ductile scratches. Both surface roughness and transmittivity are degraded due to the appearance of brittle scratches while ductile scratches make little difference to surface roughness and transmittance. However, ductile and brittle scratches greatly increase the density of damage about one order of magnitude relative to unscratched surface. In particular, ductile scratches also play an unignorable role in laser induced damage, which is different from previous knowledge. Furthermore, ZrO2 and Al2O3 polished surfaces appear to perform best in terms of damage density. PMID:27703218

  14. Quantifying clustered DNA damage induction and repair by gel electrophoresis, electronic imaging and number average length analysis

    NASA Technical Reports Server (NTRS)

    Sutherland, Betsy M.; Georgakilas, Alexandros G.; Bennett, Paula V.; Laval, Jacques; Sutherland, John C.; Gewirtz, A. M. (Principal Investigator)

    2003-01-01

    Assessing DNA damage induction, repair and consequences of such damages requires measurement of specific DNA lesions by methods that are independent of biological responses to such lesions. Lesions affecting one DNA strand (altered bases, abasic sites, single strand breaks (SSB)) as well as damages affecting both strands (clustered damages, double strand breaks) can be quantified by direct measurement of DNA using gel electrophoresis, gel imaging and number average length analysis. Damage frequencies as low as a few sites per gigabase pair (10(9)bp) can be quantified by this approach in about 50ng of non-radioactive DNA, and single molecule methods may allow such measurements in DNA from single cells. This review presents the theoretical basis, biochemical requirements and practical aspects of this approach, and shows examples of their applications in identification and quantitation of complex clustered damages.

  15. Spot-shadowing optimization to mitigate damage growth in a high-energy-laser amplifier chain.

    PubMed

    Bahk, Seung-Whan; Zuegel, Jonathan D; Fienup, James R; Widmayer, C Clay; Heebner, John

    2008-12-10

    A spot-shadowing technique to mitigate damage growth in a high-energy laser is studied. Its goal is to minimize the energy loss and undesirable hot spots in intermediate planes of the laser. A nonlinear optimization algorithm solves for the complex fields required to mitigate damage growth in the National Ignition Facility amplifier chain. The method is generally applicable to any large fusion laser.

  16. Laser-induced damage threshold tests of ultrafast multilayer dielectric coatings in various environmental conditions relevant for operation of ELI beamlines laser systems

    NASA Astrophysics Data System (ADS)

    Ďurák, Michal; Velpula, Praveen Kumar; Kramer, Daniel; Cupal, Josef; Medřík, Tomáš; Hřebíček, Jan; Golasowski, Jiří; Peceli, Davorin; Kozlová, Michaela; Rus, Bedřich

    2017-01-01

    Increasing the laser-induced damage resistance of optical components is one of the major challenges in the development of Peta-watt (PW) class laser systems. The extreme light infrastructure (ELI) beamlines project will provide ultrafast laser systems with peak powers up to 10 PW available every minute and PW class beams at 10 Hz complemented by a 5-TW, 1-kHz beamline. Sustainable performance of PW class laser systems relies on the durability of the employed optical components. As part of an effort to evaluate the damage resistance of components utilized in ELI beamlines systems, damage thresholds of several optical multilayer dielectric coatings were measured with different laser parameters and in different environments. Three coatings were tested with 10 Hz and 1 kHz pulse repetition rates, and the effect of a cleaning treatment on their damage resistance was examined. To explore the damage threshold behavior at different vacuum levels, one coating was subject to tests at various residual gas pressures. No change of damage threshold in a high vacuum with respect to ambient pressure was recorded. The effect of the cleaning treatment was found to be inconsistent, suggesting that development of the optimal cleaning treatment for a given coating requires consideration of its specific properties.

  17. Retinal damage profiles and neuronal effects of laser treatment: comparison of a conventional photocoagulator and a novel 3-nanosecond pulse laser.

    PubMed

    Wood, John P M; Shibeeb, O'Sam; Plunkett, Malcolm; Casson, Robert J; Chidlow, Glyn

    2013-03-28

    To determine detailed effects to retinal cells and, in particular, neurons following laser photocoagulation using a conventional 532 nm Nd:YAG continuous wave (CW) laser. Furthermore, to determine whether a novel 3 ns pulse laser (retinal regeneration therapy; 2RT) could specifically ablate retinal pigment epithelium (RPE) cells without causing collateral damage to other retinal cells. Adult Dark Agouti (DA) rats were separated into four groups: control, CW laser (12.7 J/cm(2)/pulse, 100 ms pulse duration), or 3 ns pulse 2RT laser at one of two energy settings ("High," 2RT-H, 163 mJ/cm(2)/pulse; "Low," 2RT-L, 109 mJ/cm(2)/pulse). Animals were treated and killed after 6 hours to 7 days, and retina/RPE was analyzed by histologic assessment, Western blot, polymerase chain reaction, and immunohistochemistry. Both lasers caused focal loss of RPE cells with no destruction of Bruch's membrane; RPE cells were present at lesion sites again within 7 days of treatments. CW and 2RT-H treatments caused extensive and moderate damage, respectively, to the outer retina. There were no obvious effects to horizontal, amacrine, or ganglion cells, as defined by immunolabeling, but an activation of PKCα within bipolar cells was noted. There was little discernible damage to any cells other than the RPE with the 2RT-L treatment. Conventional laser photocoagulation caused death of RPE cells with associated widespread damage to the outer retina but little influence on the inner retina. The novel 3 ns 2RT laser, however, was able to selectively kill RPE cells without causing collateral damage to photoreceptors. Potential benefits of this laser for clinical treatment of diabetic macular edema are discussed.

  18. Assessing laser-tissue damage with bioluminescent imaging

    NASA Astrophysics Data System (ADS)

    Wilmink, Gerald J.; Opalenik, Susan R.; Beckham, Josh T.; Davidson, Jeffrey M.; Jansen, Eric D.

    2006-07-01

    Effective medical laser procedures are achieved by selecting laser parameters that minimize undesirable tissue damage. Traditionally, human subjects, animal models, and monolayer cell cultures have been used to study wound healing, tissue damage, and cellular effects of laser radiation. Each of these models has significant limitations, and consequently, a novel skin model is needed. To this end, a highly reproducible human skin model that enables noninvasive and longitudinal studies of gene expression was sought. In this study, we present an organotypic raft model (engineered skin) used in combination with bioluminescent imaging (BLI) techniques. The efficacy of the raft model was validated and characterized by investigating the role of heat shock protein 70 (hsp70) as a sensitive marker of thermal damage. The raft model consists of human cells incorporated into an extracellular matrix. The raft cultures were transfected with an adenovirus containing a murine hsp70 promoter driving transcription of luciferase. The model enables quantitative analysis of spatiotemporal expression of proteins using BLI. Thermal stress was induced on the raft cultures by means of a constant temperature water bath or with a carbon dioxide (CO2) laser (λ=10.6 µm, 0.679 to 2.262 W/cm2, cw, unfocused Gaussian beam, ωL=4.5 mm, 1 min exposure). The bioluminescence was monitored noninvasively with an IVIS 100 Bioluminescent Imaging System. BLI indicated that peak hsp70 expression occurs 4 to 12 h after exposure to thermal stress. A minimum irradiance of 0.679 W/cm2 activated the hsp70 response, and a higher irradiance of 2.262 W/cm2 was associated with a severe reduction in hsp70 response due to tissue ablation. Reverse transcription polymerase chain reaction demonstrated that hsp70 mRNA levels increased with prolonged heating exposures. Enzyme-linked immunosorbent protein assays confirmed that luciferase was an accurate surrogate for hsp70 intracellular protein levels. Hematoxylin and

  19. In situ analysis of DNA damage response and repair using laser microirradiation.

    PubMed

    Kim, Jong-Soo; Heale, Jason T; Zeng, Weihua; Kong, Xiangduo; Krasieva, Tatiana B; Ball, Alexander R; Yokomori, Kyoko

    2007-01-01

    A proper response to DNA damage is critical for the maintenance of genome integrity. However, it is difficult to study the in vivo kinetics and factor requirements of the damage recognition process in mammalian cells. In order to address how the cell reacts to DNA damage, we utilized a second harmonic (532 nm) pulsed Nd:YAG laser to induce highly concentrated damage in a small area in interphase cell nuclei and cytologically analyzed both protein recruitment and modification. Our results revealed for the first time the sequential recruitment of factors involved in two major DNA double-strand break (DSB) repair pathways, non-homologous end-joining (NHEJ) and homologous recombination (HR), and the cell cycle-specific recruitment of the sister chromatid cohesion complex cohesin to the damage site. In this chapter, the strategy developed to study the DNA damage response using the 532-nm Nd:YAG laser will be summarized.

  20. Evaluating the damage process of dynamic target by high-energy laser in ocean environment

    NASA Astrophysics Data System (ADS)

    Wang, Jing; Ye, Demao

    2013-12-01

    The high-energy laser, as one of directed energy weapon, is famous for its unique advantage of speed-of-light response which was considered as an ideal weapon against anti-ship missile. This paper commits to evaluate the damage process of missile by high-energy laser weapon. We analyze the propagation properties which are susceptible to atmospheric attenuation effects, atmospheric turbulence effects, thermal blooming effects in sky-sea atmosphere firstly. Then because laser weapons attack one target at a time and it takes several seconds at a minimum for the target engaged, a model of calculating the required t ime for damaging the attack target was built . In the end effective evaluation methods of hot-ablated and high-energy laser weapon's damaging effectiveness are made, when the body or the optical elements of the missile is irradiated by the concatenation wave laser weapon. And one of the issues just as laser power, propagation distance is changed; the model can make different evaluation. The above model can provide the theoretical basis for the high-energy laser weapon intercept anti-ship missile and tactic deraign rationality for naval ship-borne laser weapons.

  1. Interaction of laser pulse with confined plasma during exit surface nanosecond laser damage

    NASA Astrophysics Data System (ADS)

    Rubenchik, Alexander M.; Feit, Michael D.; Demos, Stavros G.

    2013-12-01

    Interpretation of spatial and time resolved images of rear surface ns laser damage in dielectrics requires understanding of the dynamic interaction of the incoming laser beam with the confined expanding plasma in the material. The detailed kinetics of the plasma, involving both expansion and retraction, depends on details of reflection and absorption in the hot material. The growth of the hot region is treated using a model previously developed to understand laser peening. The pressure is found to scale as the square root of laser intensity and drops off slowly after energy deposition is complete. For the conditions of our experimental observations in fused silica, our model predicts a pressure of about 9 GPa and a surface expansion velocity of about 1.5 km/sec, in good agreement with experimental observation.

  2. Automated laser-based barely visible impact damage detection in honeycomb sandwich composite structures

    NASA Astrophysics Data System (ADS)

    Girolamo, D.; Girolamo, L.; Yuan, F. G.

    2015-03-01

    Nondestructive evaluation (NDE) for detection and quantification of damage in composite materials is fundamental in the assessment of the overall structural integrity of modern aerospace systems. Conventional NDE systems have been extensively used to detect the location and size of damages by propagating ultrasonic waves normal to the surface. However they usually require physical contact with the structure and are time consuming and labor intensive. An automated, contactless laser ultrasonic imaging system for barely visible impact damage (BVID) detection in advanced composite structures has been developed to overcome these limitations. Lamb waves are generated by a Q-switched Nd:YAG laser, raster scanned by a set of galvano-mirrors over the damaged area. The out-of-plane vibrations are measured through a laser Doppler Vibrometer (LDV) that is stationary at a point on the corner of the grid. The ultrasonic wave field of the scanned area is reconstructed in polar coordinates and analyzed for high resolution characterization of impact damage in the composite honeycomb panel. Two methodologies are used for ultrasonic wave-field analysis: scattered wave field analysis (SWA) and standing wave energy analysis (SWEA) in the frequency domain. The SWA is employed for processing the wave field and estimate spatially dependent wavenumber values, related to discontinuities in the structural domain. The SWEA algorithm extracts standing waves trapped within damaged areas and, by studying the spectrum of the standing wave field, returns high fidelity damage imaging. While the SWA can be used to locate the impact damage in the honeycomb panel, the SWEA produces damage images in good agreement with X-ray computed tomographic (X-ray CT) scans. The results obtained prove that the laser-based nondestructive system is an effective alternative to overcome limitations of conventional NDI technologies.

  3. EFFECTS OF LASER RADIATION ON MATTER. LASER PLASMA: Thermally induced optical damage to barium-sodium niobate crystals

    NASA Astrophysics Data System (ADS)

    Baryshev, S. A.; Goncharova, I. F.; Konvisar, P. G.; Kuznetsov, V. A.

    1990-06-01

    Thermally induced optical damage (TIOD) was observed in undoped barium-sodium niobate (BSN) crystals as a result of changes in their temperature. This damage was deduced from the behavior of YAG:Nd3+ laser radiation when a BSN crystal was inserted in the resonator and also using a helium-neon laser probe beam. The experimental results were satisfactorily explained by the familiar pyroelectric model of TIOD and, in the crystals studied, an inhomogeneity of the conductivity rather than an inhomogeneity of the pyroelectric constant played the main role.

  4. Evaluating the thermal damage resistance of graphene/carbon nanotube hybrid composite coatings

    NASA Astrophysics Data System (ADS)

    David, L.; Feldman, A.; Mansfield, E.; Lehman, J.; Singh, G.

    2014-03-01

    We study laser irradiation behavior of multiwalled carbon nanotubes (MWCNT) and chemically modified graphene (rGO)-composite spray coatings for use as a thermal absorber material for high-power laser calorimeters. Spray coatings on aluminum test coupon were exposed to increasing laser irradiance for extended exposure times to quantify their damage threshold and optical absorbance. The coatings, prepared at varying mass % of MWCNTs in rGO, demonstrated significantly higher damage threshold values at 2.5 kW laser power at 10.6 μm wavelength than carbon paint or MWCNTs alone. Electron microscopy and Raman spectroscopy of irradiated specimens show that the coating prepared at 50% CNT loading endure at least 2 kW.cm-2 for 10 seconds without significant damage. The improved damage resistance is attributed to the unique structure of the composite in which the MWCNTs act as an efficient absorber of laser light while the much larger rGO sheets surrounding them, dissipate the heat over a wider area.

  5. Combined Advanced Finishing and UV-Laser Conditioning for Producing UV-Damage-Resistant Fused Silica Optics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Menapace, J A; Penetrante, B; Golini, D

    2001-11-01

    Laser induced damage initiation on fused silica optics can limit the lifetime of the components when used in high power UV laser environments. Foe example in inertial confinement fusion research applications, the optics can be exposed to temporal laser pulses of about 3-nsec with average fluences of 8 J/cm{sup 2} and peak fluences between 12 and 15 J/cm{sup 2}. During the past year, we have focused on optimizing the damage performance at a wavelength of 355-nm (3{omega}), 3-nsec pulse length, for optics in this category by examining a variety of finishing technologies with a challenge to improve the laser damagemore » initiation density by at least two orders of magnitude. In this paper, we describe recent advances in improving the 3{omega} damage initiation performance of laboratory-scale zirconium oxide and cerium oxide conventionally finished fused silica optics via application of processes incorporating magnetorheological finishing (MRF), wet chemical etching, and UV laser conditioning. Details of the advanced finishing procedures are described and comparisons are made between the procedures based upon large area 3{omega} damage performance, polishing layer contamination, and optical subsurface damage.« less

  6. Comparative analysis of different laser systems to study cellular responses to DNA damage in mammalian cells

    PubMed Central

    Kong, Xiangduo; Mohanty, Samarendra K.; Stephens, Jared; Heale, Jason T.; Gomez-Godinez, Veronica; Shi, Linda Z.; Kim, Jong-Soo; Yokomori, Kyoko; Berns, Michael W.

    2009-01-01

    Proper recognition and repair of DNA damage is critical for the cell to protect its genomic integrity. Laser microirradiation ranging in wavelength from ultraviolet A (UVA) to near-infrared (NIR) can be used to induce damage in a defined region in the cell nucleus, representing an innovative technology to effectively analyze the in vivo DNA double-strand break (DSB) damage recognition process in mammalian cells. However, the damage-inducing characteristics of the different laser systems have not been fully investigated. Here we compare the nanosecond nitrogen 337 nm UVA laser with and without bromodeoxyuridine (BrdU), the nanosecond and picosecond 532 nm green second-harmonic Nd:YAG, and the femtosecond NIR 800 nm Ti:sapphire laser with regard to the type(s) of damage and corresponding cellular responses. Crosslinking damage (without significant nucleotide excision repair factor recruitment) and single-strand breaks (with corresponding repair factor recruitment) were common among all three wavelengths. Interestingly, UVA without BrdU uniquely produced base damage and aberrant DSB responses. Furthermore, the total energy required for the threshold H2AX phosphorylation induction was found to vary between the individual laser systems. The results indicate the involvement of different damage mechanisms dictated by wavelength and pulse duration. The advantages and disadvantages of each system are discussed. PMID:19357094

  7. Extracting the distribution of laser damage precursors on fused silica surfaces for 351 nm, 3 ns laser pulses at high fluences (20-150 J/cm2).

    PubMed

    Laurence, Ted A; Bude, Jeff D; Ly, Sonny; Shen, Nan; Feit, Michael D

    2012-05-07

    Surface laser damage limits the lifetime of optics for systems guiding high fluence pulses, particularly damage in silica optics used for inertial confinement fusion-class lasers (nanosecond-scale high energy pulses at 355 nm/3.5 eV). The density of damage precursors at low fluence has been measured using large beams (1-3 cm); higher fluences cannot be measured easily since the high density of resulting damage initiation sites results in clustering. We developed automated experiments and analysis that allow us to damage test thousands of sites with small beams (10-30 µm), and automatically image the test sites to determine if laser damage occurred. We developed an analysis method that provides a rigorous connection between these small beam damage test results of damage probability versus laser pulse energy and the large beam damage results of damage precursor densities versus fluence. We find that for uncoated and coated fused silica samples, the distribution of precursors nearly flattens at very high fluences, up to 150 J/cm2, providing important constraints on the physical distribution and nature of these precursors.

  8. Laser damage metrology in biaxial nonlinear crystals using different test beams

    NASA Astrophysics Data System (ADS)

    Hildenbrand, Anne; Wagner, Frank R.; Akhouayri, Hassan; Natoli, Jean-Yves; Commandre, Mireille

    2008-01-01

    Laser damage measurements in nonlinear optical crystals, in particular in biaxial crystals, may be influenced by several effects proper to these materials or greatly enhanced in these materials. Before discussion of these effects, we address the topic of error bar determination for probability measurements. Error bars for the damage probabilities are important because nonlinear crystals are often small and expensive, thus only few sites are used for a single damage probability measurement. We present the mathematical basics and a flow diagram for the numerical calculation of error bars for probability measurements that correspond to a chosen confidence level. Effects that possibly modify the maximum intensity in a biaxial nonlinear crystal are: focusing aberration, walk-off and self-focusing. Depending on focusing conditions, propagation direction, polarization of the light and the position of the focus point in the crystal, strong aberrations may change the beam profile and drastically decrease the maximum intensity in the crystal. A correction factor for this effect is proposed, but quantitative corrections are not possible without taking into account the experimental beam profile after the focusing lens. The characteristics of walk-off and self-focusing have quickly been reviewed for the sake of completeness of this article. Finally, parasitic second harmonic generation may influence the laser damage behavior of crystals. The important point for laser damage measurements is that the amount of externally observed SHG after the crystal does not correspond to the maximum amount of second harmonic light inside the crystal.

  9. Damage modeling and statistical analysis of optics damage performance in MJ-class laser systems.

    PubMed

    Liao, Zhi M; Raymond, B; Gaylord, J; Fallejo, R; Bude, J; Wegner, P

    2014-11-17

    Modeling the lifetime of a fused silica optic is described for a multiple beam, MJ-class laser system. This entails combining optic processing data along with laser shot data to account for complete history of optic processing and shot exposure. Integrating with online inspection data allows for the construction of a performance metric to describe how an optic performs with respect to the model. This methodology helps to validate the damage model as well as allows strategic planning and identifying potential hidden parameters that are affecting the optic's performance.

  10. Investigation of Laser-Induced Retinal Damage: Wavelength and Pulsewidth Dependent Mechanisms

    DTIC Science & Technology

    1994-08-31

    transformation. Biochim Biophys Acta 1991; 1072:129-57. 2. Artuc M, Ramshad M, Kappus H. Studies on acute toxic effects to keratinocytes induced by...hematoporphyrin derivatives and laser light Arch Dermatol Res 1989;281:491-4. 3. Artuc M, Ramshad M, Reinhold C, Kappus H. DNA damage caused by laser light

  11. Damage Thresholds for Exposure to NIR and Blue Lasers in an In Vitro RPE Cell System

    DTIC Science & Technology

    2006-07-01

    damage , and to identify antioxidants capable of protecting these cells from laser-in- duced cell death. MATERIALS AND METHODS The human RPE cell...melanosomes in blue laser-induced damage in vitro, which confirms the view that melanin plays an important role in photochemical damage mechanisms in...community has only a validating role in the animal ED50 damage threshold data used by safety committees. Systems of in vitro analysis must be

  12. Analysis of the Damage Mechanism Related to CO2 Laser Cochleostomy on Guinea Pig Cochlea

    PubMed Central

    Liu, Xiang; Qian, Xiao-qing; Ma, Rui

    2016-01-01

    Different types of lasers have been used in inner ear surgery. Therefore, it is of the utmost importance to avoid damage to the inner ear (e.g., hyperthermia and acoustic effects) caused by the use of such lasers. The aim of this study was to use a high powered fibre-enabled CO2 laser (10 W, 606 J/cm2) to perform cochleostomies on guinea pig cochlea and to investigate the possible laser-induced damage mechanisms. The temperature changes in the round window membrane, auditory evoked brainstem response, and morphological of the hair cells were measured and recorded before and after laser application. All of the outcomes differed in comparison with the control group. A rise in temperature and subsequent increased hearing loss were observed in animals that underwent surgery with a 10 W CO2 laser. These findings correlated with increased injury to the cochlear ultrastructure and a higher positive expression of E-cadherin and β-catenin in the damaged organ of Corti. We assume that enhanced cell-cell adhesion and the activated β-catenin-related canonical Wnt-signalling pathway may play a role in the protection of the cochlea to prevent further damage. PMID:28070426

  13. Excimer laser debridement of necrotic erosions of skin without collateral damage

    NASA Astrophysics Data System (ADS)

    Wynne, James J.; Felsenstein, Jerome M.; Trzcinski, Robert; Zupanski-Nielsen, Donna; Connors, Daniel P.

    2011-07-01

    Pulsed ArF excimer laser radiation at 6.4 eV, at fluence exceeding the ablation threshold, will debride burn eschar and other dry necrotic erosions of the skin. Debridement will cease when sufficiently moist viable tissue is exposed, due to absorption by aqueous chloride ions (Cl-) through the non-thermal process of electron photodetachment, thereby inhibiting collateral damage to the viable tissue. ArF excimer laser radiation debrides/ablates ~1 micron of tissue with each pulse. While this provides great precision in controlling the depth of debridement, the process is relatively time-consuming. In contrast, XeCl excimer laser radiation debrides ~8 microns of tissue with each pulse. However the 4.0 eV photon energy of the XeCl excimer laser is insufficient to photodetach an electron from a Cl- ion, so blood or saline will not inhibit debridement. Consequently, a practical laser debridement system should incorporate both lasers, used in sequence. First, the XeCl excimer laser would be used for accelerated debridement. When the necrotic tissue is thinned to a predetermined thickness, the ArF excimer laser would be used for very precise and well-controlled debridement, removing ultra-thin layers of material with each pulse. Clearly, the use of the ArF laser is very desirable when debriding very close to the interface between necrotic tissue and viable tissue, where the overall speed of debridement need not be so rapid and collateral damage to viable tissue is undesirable. Such tissue will be sterile and ready for further treatment, such as a wound dressing and/or a skin graft.

  14. Impact of different cleaning processes on the laser damage threshold of antireflection coatings for Z-Backlighter optics at Sandia National Laboratories

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Field, Ella; Bellum, John; Kletecka, Damon

    We have examined how different cleaning processes affect the laser-induced damage threshold of antireflection coatings for large dimension, Z-Backlighter laser optics at Sandia National Laboratories. Laser damage thresholds were measured after the coatings were created, and again 4 months later to determine which cleaning processes were most effective. There is a nearly twofold increase in laser-induced damage threshold between the antireflection coatings that were cleaned and those that were not cleaned. Aging of the coatings after 4 months resulted in even higher laser-induced damage thresholds. Also, the laser-induced damage threshold results revealed that every antireflection coating had a high defectmore » density, despite the cleaning process used, which indicates that improvements to either the cleaning or deposition processes should provide even higher laser-induced damage thresholds.« less

  15. Impact of different cleaning processes on the laser damage threshold of antireflection coatings for Z-Backlighter optics at Sandia National Laboratories

    DOE PAGES

    Field, Ella; Bellum, John; Kletecka, Damon

    2014-11-06

    We have examined how different cleaning processes affect the laser-induced damage threshold of antireflection coatings for large dimension, Z-Backlighter laser optics at Sandia National Laboratories. Laser damage thresholds were measured after the coatings were created, and again 4 months later to determine which cleaning processes were most effective. There is a nearly twofold increase in laser-induced damage threshold between the antireflection coatings that were cleaned and those that were not cleaned. Aging of the coatings after 4 months resulted in even higher laser-induced damage thresholds. Also, the laser-induced damage threshold results revealed that every antireflection coating had a high defectmore » density, despite the cleaning process used, which indicates that improvements to either the cleaning or deposition processes should provide even higher laser-induced damage thresholds.« less

  16. Neodymium: YAG laser damage threshold. A comparison of injection-molded and lathe-cut polymethylmethacrylate intraocular lenses.

    PubMed

    Wilson, S E; Brubaker, R F

    1987-01-01

    The possibility that injection-molded intraocular lenses (IOLs) with imperfections called iridescent clefts could have a decreased threshold to neodymium: YAG (Nd:YAG) laser-induced damage was investigated. Thresholds for Nd:YAG laser-induced damage were determined for injection-molded and lathe-cut polymethylmethacrylate lenses. When aimed at a membrane in contact with a posterior convex surface, the average thresholds were 0.96 +/- 0.18 mJ (Standard deviation [SD]) and 1.80 +/- 0.55 mJ, respectively. The difference was significant at P = 0.001. When injection-molding polymethylmethacrylate was used to make lathe-cut IOLs, very few iridescent clefts were present, and the threshold to Nd:YAG laser-induced damage was 0.94 +/- 0.25 mJ. Iridescent clefts are therefore produced during the injection-molding process but they do not lower the threshold to Nd:YAG laser-induced damage. Rather, the reduced threshold in injection-molded lenses is most probably a result of the polymethylmethacrylate used in their manufacture. Clinically, iridescent clefts in a lens suggest that it has been manufactured by an injection-molding process and that Nd:YAG laser posterior capsulotomy must be performed at the lowest possible energy level to avoid damage.

  17. Limits of performance: CW laser damage

    NASA Astrophysics Data System (ADS)

    Shah, Rashmi S.; Rey, Justin J.; Stewart, Alan F.

    2007-01-01

    High performance optical coatings are an enabling technology for many applications - navigation systems, telecom, fusion, advanced measurement systems of many types as well as directed energy weapons. The results of recent testing of superior optical coatings conducted at high flux levels have been presented. Failure of these coatings was rare. However, induced damage was not expected from simple thermal models relating flux loading to induced temperatures. Clearly, other mechanisms must play a role in the occurrence of laser damage. Contamination is an obvious mechanism-both particulate and molecular. Less obvious are structural defects and the role of induced stresses. These mechanisms are examined through simplified models and finite element analysis. The results of the models are compared to experiment, for induced temperatures and observed stress levels. The role of each mechanism is described and limiting performance is determined.

  18. Enhanced thermomechanical stability on laser-induced damage by functionally graded layers in quasi-rugate filters

    NASA Astrophysics Data System (ADS)

    Pu, Yunti; Ma, Ping; Lv, Liang; Zhang, Mingxiao; Lu, Zhongwen; Qiao, Zhao; Qiu, Fuming

    2018-05-01

    Ta2O5-SiO2 quasi-rugate filters with a reasonable optimization of rugate notch filter design were prepared by ion-beam sputtering. The optical properties and laser-induced damage threshold are studied. Compared with the spectrum of HL-stacks, the spectrum of quasi-rugate filters have weaker second harmonic peaks and narrower stopbands. According to the effect of functionally graded layers (FGLs), 1-on-1 and S-on-1 Laser induced damage threshold (LIDT) of quasi-rugate filters are about 22% and 50% higher than those of HL stacks, respectively. Through the analysis of the damage morphologies, laser-induced damage of films under nanosecond multi-pulse are dominated by a combination of thermal shock stress and thermomechanical instability due to nodules. Compared with catastrophic damages, the damage sits of quasi-rugate filters are developed in a moderate way. The damage growth behavior of defect-induced damage sites have been effectively restrained by the structure of FGLs. Generally, FGLs are used to reduce thermal stress by the similar thermal-expansion coefficients of neighboring layers and solve the problems such as instability and cracking raised by the interface discontinuity of nodular boundaries, respectively.

  19. Quantifying stochasticity in the dynamics of delay-coupled semiconductor lasers via forbidden patterns.

    PubMed

    Tiana-Alsina, Jordi; Buldú, Javier M; Torrent, M C; García-Ojalvo, Jordi

    2010-01-28

    We quantify the level of stochasticity in the dynamics of two mutually coupled semiconductor lasers. Specifically, we concentrate on a regime in which the lasers synchronize their dynamics with a non-zero lag time, and the leader and laggard roles alternate irregularly between the lasers. We analyse this switching dynamics in terms of the number of forbidden patterns of the alternate time series. The results reveal that the system operates in a stochastic regime, with the level of stochasticity decreasing as the lasers are pumped further away from their lasing threshold. This behaviour is similar to that exhibited by a single semiconductor laser subject to external optical feedback, as its dynamics shifts from the regime of low-frequency fluctuations to coherence collapse. This journal is © 2010 The Royal Society

  20. Validity of reciprocity rule on mouse skin thermal damage due to CO2 laser irradiation

    NASA Astrophysics Data System (ADS)

    Parvin, P.; Dehghanpour, H. R.; Moghadam, M. S.; Daneshafrooz, V.

    2013-07-01

    CO2 laser (10.6 μm) is a well-known infrared coherent light source as a tool in surgery. At this wavelength there is a high absorbance coefficient (860 cm-1), because of vibration mode resonance of H2O molecules. Therefore, the majority of the irradiation energy is absorbed in the tissue and the temperature of the tissue rises as a function of power density and laser exposure duration. In this work, the tissue damage caused by CO2 laser (1-10 W, ˜40-400 W cm-2, 0.1-6 s) was measured using 30 mouse skin samples. Skin damage assessment was based on measurements of the depth of cut, mean diameter of the crater and the carbonized layer. The results show that tissue damage as assessed above parameters increased with laser fluence and saturated at 1000 J cm-2. Moreover, the damage effect due to high power density at short duration was not equivalent to that with low power density at longer irradiation time even though the energy delivered was identical. These results indicate the lack of validity of reciprocity (Bunsen-Roscoe) rule for the thermal damage.

  1. Impact of mechanical stress induced in silica vacuum windows on laser-induced damage.

    PubMed

    Gingreau, Clémence; Lanternier, Thomas; Lamaignère, Laurent; Donval, Thierry; Courchinoux, Roger; Leymarie, Christophe; Néauport, Jérôme

    2018-04-15

    At the interface between vacuum and air, optical windows must keep their optical properties, despite being subjected to mechanical stress. In this Letter, we investigate the impact of such stress on the laser-induced damage of fused silica windows at the wavelength of 351 nm in the nanosecond regime. Different stress values, from 1 to 30 MPa, both tensile and compressive, were applied. No effect of the stress on the laser-induced damage was evidenced.

  2. Laser induced damage in optical materials: eleventh ASTM symposium.

    PubMed

    Bennett, H E; Glass, A J; Guenther, A H; Newnam, B

    1980-07-15

    The eleventh Symposium on Optical Materials for High-Power Lasers (Boulder Damage Symposium) was held at the National Bureau of Standards in Boulder, Colorado, 30-31 October 1979. The symposium was held under the auspices of ASTM Committee F-1, Subcommittee on Laser Standards, with the joint sponsorship of NBS, the Defense Advanced Research Projects Agency, the Department of Energy, and the Office of Naval Research. About 150 scientists attended the symposium, including representatives of the United Kingdom, France, Canada, Japan, West Germany, and Denmark. The symposium was divided into sessions concerning transparent optical materials and the measurement of their properties, mirrors and surfaces, thin film characteristics, thin film damage, considerations for high-power systems, and finally theory and breakdown. As in previous years, the emphasis of the papers presented at the symposium was directed toward new frontiers and new developments. Particular emphasis was given to materials for high-power apparatus. The wavelength range of prime interest was from 10.6 microm to the UV region. Highlights included surface characterization, thin film-substrate boundaries, and advances in fundamental laser-matter threshold interactions and mechanisms. The scaling of damage thresholds with pulse duration, focal area, and wavelength was discussed in detail. Harold E. Bennett of the Naval Weapons Center, Alexander J. Glass of the Lawrence Livermore Laboratory, Arthur H. Guenther of the Air Force Weapons Laboratory, and Brian E. Newnam of the Los Alamos Scientific Laboratory were cochairpersons. The twelfth annual symposium is scheduled for 30 September-1 October 1980 at the National Bureau of Standards, Boulder, Colorado.

  3. 355 nm and 1064 nm-pulse mixing to identify the laser-induced damage mechanisms in KDP

    NASA Astrophysics Data System (ADS)

    Reyné, Stéphane; Duchateau, Guillaume; Natoli, Jean-Yves; Lamaignère, Laurent

    2011-02-01

    Nanosecond laser-induced damage (LID) in potassium dihydrogen phosphate (KH2PO4 or KDP) remains an issue for light-frequency converters in large-aperture lasers such as NIF (National Ignition Facility, in USA) LMJ (Laser MegaJoule, in France). In the final optic assembly, converters are simultaneously illuminated by multiple wavelengths during the frequency conversion. In this configuration, the damage resistance of the KDP crystals becomes a crucial problem and has to be improved. In this study, we propose a refined investigation about the LID mechanisms involved in the case of a multiple wavelengths combination. Experiments based on an original pump-pump set-up have been carried out in the nanosecond regime on a KDP crystal. In particular, the impact of a simultaneous mixing of 355 nm and 1064 nm pulses has been experimentally studied and compared to a model based on heat transfer, the Mie theory and a Drude model. This study sheds light on the physical processes implied in the KDP laser damage. In particular, a three-photon ionization mechanism is shown to be responsible for laser damage in KDP.

  4. DNA Damage in Bone Marrow Cells Induced by Femtosecond and Nanosecond Ultraviolet Laser Pulses.

    PubMed

    Morkunas, Vaidotas; Gabryte, Egle; Vengris, Mikas; Danielius, Romualdas; Danieliene, Egle; Ruksenas, Osvaldas

    2015-12-01

    The purpose of this study was to investigate the possible genotoxic impact of new generation 205 nm femtosecond solid-state laser irradiation on the DNA of murine bone marrow cells in vitro, and to compare the DNA damage caused by both femtosecond and nanosecond UV laser pulses. Recent experiments of corneal stromal ablation in vitro and in vivo applying femtosecond UV pulses showed results comparable with or superior to those obtained using nanosecond UV lasers. However, the possible genotoxic effect of ultrashort laser pulses was not investigated. Mouse bone marrow cells were exposed to different doses of 205 nm femtosecond, 213 and 266 nm nanosecond lasers, and 254 nm UV lamp irradiation. The comet assay was used for the evaluation of DNA damage. All types of irradiation demonstrated intensity-dependent genotoxic impact. The DNA damage induced depended mainly upon wavelength rather than on other parameters such as pulse duration, repetition rate, or beam delivery to a target. Both 205 nm femtosecond and clinically applied 213 nm nanosecond lasers' pulses induced a comparable amount of DNA breakage in cells exposed to the same irradiation dose. To further evaluate the suitability of femtosecond UV laser sources for microsurgery, a separate investigation of the genotoxic and mutagenic effects on corneal cells in vitro and, particularly, in vivo is needed.

  5. Using a cover layer to improve the damage resistance of gold-coated gratings induced by a picosecond pulsed laser

    NASA Astrophysics Data System (ADS)

    Xia, Zhilin; Wu, Yihan; Kong, Fanyu; Jin, Yunxia

    2018-04-01

    The chirped pulse amplification (CPA) technology is the main approach to achieve high-intensity short-pulse laser. Diffraction gratings are good candidates for stretching and compressing laser pulses in CPA. In this paper, a kind of gold-coated grating has been prepared and its laser damage experiment has been performed. The results reflect that the gratings laser damage was dominated by thermal ablation due to gold films or inclusions absorption and involved the deformation or eruption of the gold film. Based on these damage phenomena, a method of using a cover layer to prevent gold films from deforming and erupting has been adopted to improve the gold-coated gratings laser damage threshold. Since the addition of a cover layer changes the gratings diffraction efficiency, the gratings structure has been re-optimized. Furthermore, according to the calculated thermal stress distributions in gratings with optimized structures, the cover layer was demonstrated to be helpful for improving the gratings laser damage resistance if it is thick enough.

  6. Residual stress and damage-induced critical fracture on CO2 laser treated fused silica

    NASA Astrophysics Data System (ADS)

    Matthews, M. J.; Stolken, J. S.; Vignes, R. M.; Norton, M. A.; Yang, S.; Cooke, J. D.; Guss, G. M.; Adams, J. J.

    2009-10-01

    Localized damage repair and polishing of silica-based optics using mid- and far-IR CO2 lasers has been shown to be an effective method for increasing optical damage threshold in the UV. However, it is known that CO2 laser heating of silicate surfaces can lead to a level of residual stress capable of causing critical fracture either during or after laser treatment. Sufficient control of the surface temperature as a function of time and position is therefore required to limit this residual stress to an acceptable level to avoid critical fracture. In this work we present the results of 351 nm, 3ns Gaussian damage growth experiments within regions of varying residual stress caused by prior CO2 laser exposures. Thermally stressed regions were non-destructively characterized using polarimetry and confocal Raman microscopy to measure the stress induced birefringence and fictive temperature respectively. For 1~40s square pulse CO2 laser exposures created over 0.5-1.25kW/cm2 with a 1-3mm 1/e2 diameter beam (Tmax~1500-3000K), the critical damage site size leading to fracture increases weakly with peak temperature, but shows a stronger dependence on cooling rate, as predicted by finite element hydrodynamics simulations. Confocal micro-Raman was used to probe structural changes to the glass over different thermal histories and indicated a maximum fictive temperature of 1900K for Tmax>=2000K. The effect of cooling rate on fictive temperature caused by CO2 laser heating are consistent with finite element calculations based on a Tool-Narayanaswamy relaxation model.

  7. Width of thermal damage after using the YAG contact laser for cutting biological tissue: animal experimental investigation.

    PubMed

    Mecke, H; Schünke, M; Schnaidt, S; Freys, I; Semm, K

    1991-01-01

    At the University Women's Clinic in Kiel, the YAG contact laser has been used as a cutting instrument in pelviscopic operations since 1987. When the laser cuts, it produces only a scant amount of mechanical trauma. The determining factor is the amount of thermal damage produced along the wound margins and in direct neighboring tissue. The extent of the tissue change seen in the uterus and liver parenchyma of rats and the striated muscle of rabbits after application of the YAG contact laser was demonstrated using various staining techniques and stains. Liver parenchyma proved to be the most sensitive to thermal damage. In the uterine horn, enzyme-histochemical ATPase and alkaline phosphatase demonstrations showed a significantly wider zone of thermal damage after laser incision than did hematoxylin-eosin and Goldner staining techniques. A good understanding of the extent of thermal damage is essential for atraumatic pelviscopic operations using the YAG contact laser and also for the preventing of complications.

  8. Damage Threshold of In Vivo Rabbit Cornea by 2 micron Laser Irradiation

    DTIC Science & Technology

    2007-01-01

    in laser injury experiments? Implications for human exposure limits. Health Phys 2002; 82(3):335-347. 11. Siegman AE, Sasnett MW, Johnston TF. Choice... Laser Irradiation DISTRIBUTION: Approved for public release, distribution unlimited This paper is part of the following report: TITLE: Conference on...part numbers comprise the compilation report: ADP023676 thru ADP023710 UNCLASSIFIED Damage Threshold of In Vivo Rabbit Cornea by 2 gm Laser Irradiation

  9. Femtosecond near-infrared laser microirradiation reveals a crucial role for PARP signaling on factor assemblies at DNA damage sites

    PubMed Central

    Saquilabon Cruz, Gladys Mae; Kong, Xiangduo; Silva, Bárbara Alcaraz; Khatibzadeh, Nima; Thai, Ryan; Berns, Michael W.; Yokomori, Kyoko

    2016-01-01

    Laser microirradiation is a powerful tool for real-time single-cell analysis of the DNA damage response (DDR). It is often found, however, that factor recruitment or modification profiles vary depending on the laser system employed. This is likely due to an incomplete understanding of how laser conditions/dosages affect the amounts and types of damage and the DDR. We compared different irradiation conditions using a femtosecond near-infrared laser and found distinct damage site recruitment thresholds for 53BP1 and TRF2 correlating with the dose-dependent increase of strand breaks and damage complexity. Low input-power microirradiation that induces relatively simple strand breaks led to robust recruitment of 53BP1 but not TRF2. In contrast, increased strand breaks with complex damage including crosslinking and base damage generated by high input-power microirradiation resulted in TRF2 recruitment to damage sites with no 53BP1 clustering. We found that poly(ADP-ribose) polymerase (PARP) activation distinguishes between the two damage states and that PARP activation is essential for rapid TRF2 recruitment while suppressing 53BP1 accumulation at damage sites. Thus, our results reveal that careful titration of laser irradiation conditions allows induction of varying amounts and complexities of DNA damage that are gauged by differential PARP activation regulating protein assembly at the damage site. PMID:26424850

  10. Research on laser-induced damage resistance of fused silica optics by the fluid jet polishing method.

    PubMed

    Lv, Liang; Ma, Ping; Huang, Jinyong; He, Xiang; Cai, Chao; Zhu, Heng

    2016-03-20

    Laser-induced damage threshold (LIDT) is one important evaluation index for optical glasses applied in large laser instruments which are exposed to high light irradiation flux. As a new kind of precise polishing technology, fluid jet polishing (FJP) has been widely used in generating planar, spherical, and aspherical optics with high-accuracy surfaces. Laser damage resistances of fused silica optics by the FJP process are studied in this paper. Fused silica samples with various FJP parameters are prepared, and laser damage experiments are performed with 351 nm wavelength and a 5.5 ns pulse width laser. Experimental results demonstrate that the LIDT of the samples treated with FJP processes did not increase, compared to their original state. The surface quality of the samples is one factor for the decrease of LIDT. For ceria solution polished samples, the cerium element remaining is another factor of the lower LIDT.

  11. Laser Induced Damage of Potassium Dihydrogen Phosphate (KDP) Optical Crystal Machined by Water Dissolution Ultra-Precision Polishing Method

    PubMed Central

    Gao, Hang; Wang, Xu; Guo, Dongming; Liu, Ziyuan

    2018-01-01

    Laser induced damage threshold (LIDT) is an important optical indicator for nonlinear Potassium Dihydrogen Phosphate (KDP) crystal used in high power laser systems. In this study, KDP optical crystals are initially machined with single point diamond turning (SPDT), followed by water dissolution ultra-precision polishing (WDUP) and then tested with 355 nm nanosecond pulsed-lasers. Power spectral density (PSD) analysis shows that WDUP process eliminates the laser-detrimental spatial frequencies band of micro-waviness on SPDT machined surface and consequently decreases its modulation effect on the laser beams. The laser test results show that LIDT of WDUP machined crystal improves and its stability has a significant increase by 72.1% compared with that of SPDT. Moreover, a subsequent ultrasonic assisted solvent cleaning process is suggested to have a positive effect on the laser performance of machined KDP crystal. Damage crater investigation indicates that the damage morphologies exhibit highly thermal explosion features of melted cores and brittle fractures of periphery material, which can be described with the classic thermal explosion model. The comparison result demonstrates that damage mechanisms for SPDT and WDUP machined crystal are the same and WDUP process reveals the real bulk laser resistance of KDP optical crystal by removing the micro-waviness and subsurface damage on SPDT machined surface. This improvement of WDUP method makes the LIDT more accurate and will be beneficial to the laser performance of KDP crystal. PMID:29534032

  12. Quantifying the risks of winter damage on overwintering crops under future climates: Will low-temperature damage be more likely in warmer climates?

    NASA Astrophysics Data System (ADS)

    Vico, G.; Weih, M.

    2014-12-01

    Autumn-sown crops act as winter cover crop, reducing soil erosion and nutrient leaching, while potentially providing higher yields than spring varieties in many environments. Nevertheless, overwintering crops are exposed for longer periods to the vagaries of weather conditions. Adverse winter conditions, in particular, may negatively affect the final yield, by reducing crop survival or its vigor. The net effect of the projected shifts in climate is unclear. On the one hand, warmer temperatures may reduce the frequency of low temperatures, thereby reducing damage risk. On the other hand, warmer temperatures, by reducing plant acclimation level and the amount and duration of snow cover, may increase the likelihood of damage. Thus, warmer climates may paradoxically result in more extensive low temperature damage and reduced viability for overwintering plants. The net effect of a shift in climate is explored by means of a parsimonious probabilistic model, based on a coupled description of air temperature, snow cover, and crop tolerable temperature. Exploiting an extensive dataset of winter wheat responses to low temperature exposure, the risk of winter damage occurrence is quantified under conditions typical of northern temperate latitudes. The full spectrum of variations expected with climate change is explored, quantifying the joint effects of alterations in temperature averages and their variability as well as shifts in precipitation. The key features affecting winter wheat vulnerability to low temperature damage under future climates are singled out.

  13. Determination of ultra-short laser induced damage threshold of KH{sub 2}PO{sub 4} crystal: Numerical calculation and experimental verification

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cheng, Jian; Department of Physics, The Ohio State University, 191 W. Woodruff Ave, Columbus, OH 43210; Chen, Mingjun, E-mail: chenmj@hit.edu.cn, E-mail: chowdhury.24@osu.edu

    Rapid growth and ultra-precision machining of large-size KDP (KH{sub 2}PO{sub 4}) crystals with high laser damage resistance are tough challenges in the development of large laser systems. It is of high interest and practical significance to have theoretical models for scientists and manufacturers to determine the laser-induced damage threshold (LIDT) of actually prepared KDP optics. Here, we numerically and experimentally investigate the laser-induced damage on KDP crystals in ultra-short pulse laser regime. On basis of the rate equation for free electron generation, a model dedicated to predicting the LIDT is developed by considering the synergistic effect of photoionization, impact ionizationmore » and decay of electrons. Laser damage tests are performed to measure the single-pulse LIDT with several testing protocols. The testing results combined with previously reported experimental data agree well with those calculated by the model. By taking the light intensification into consideration, the model is successfully applied to quantitatively evaluate the effect of surface flaws inevitably introduced in the preparation processes on the laser damage resistance of KDP crystals. This work can not only contribute to further understanding of the laser damage mechanisms of optical materials, but also provide available models for evaluating the laser damage resistance of exquisitely prepared optical components used in high power laser systems.« less

  14. The optical effect of a semiconductor laser on protecting wheat from UV-B radiation damage.

    PubMed

    Qiu, Zong-Bo; Zhu, Xin-Jun; Li, Fang-Min; Liu, Xiao; Yue, Ming

    2007-07-01

    Lasers have been widely used in the field of biology along with the development of laser technology, but the mechanism of the bio-effect of lasers is not explicit. The objective of this paper was to test the optical effect of a laser on protecting wheat from UV-B damage. A patent instrument was employed to emit semiconductor laser (wavelength 650 nm) and incoherent red light, which was transformed from the semiconductor laser. The wavelength, power and lightfleck diameter of the incoherent red light are the same as those of the semiconductor laser. The semiconductor laser (wavelength 650 nm, power density 3.97 mW mm(-2)) and incoherent red light (wavelength 650 nm, power density 3.97 mW mm(-2)) directly irradiated the embryo of wheat seeds for 3 min respectively, and when the seedlings were 12-day-old they were irradiated by UV-B radiation (10.08 kJ m(-2)) for 12 h in the dark. Changes in the concentration of malondialdehyde (MDA), hydrogen peroxide (H(2)O(2)), glutathione (GSH), ascorbate (AsA), carotenoids (CAR), the production rate of superoxide radical (O(2)(-)), the activities of peroxidase (POD), catalase (CAT), superoxide dismutase (SOD) and the growth parameters of seedlings (plant height, leaf area and fresh weight) were measured to test the optical effect of the laser. The results showed that the incoherent red light treatment could not enhance the activities of SOD, POD and CAT and the concentration of AsA and CAR. When the plant cells were irradiated by UV-B, the incoherent red light treatment could not eliminate active oxygen and prevent lipid peroxidation in wheat. The results also clearly demonstrate that the plant DNA was damaged by UV-B radiation and semiconductor laser irradiance had the capability to protect plants from UV-B-induced DNA damage, while the incoherent red light could not. This is the first investigation reporting the optical effect of a semiconductor laser on protecting wheat from UV-B radiation damage.

  15. Qualification and Testing of Quantum Cascade Lasers for Harsh Environments

    NASA Astrophysics Data System (ADS)

    Brauer, C. S.; Myers, T. L.; Cannon, B. D.; Anderson, C. G.; Crowther, B. G.; Hansen, S.

    2014-12-01

    Quantum cascade lasers (QCLs) offer the potential for the development of novel, laser-based instruments for both terrestrial and space applications. In order to withstand harsh conditions encountered in these environments, lasers must be robust, and rigorous testing is required before new systems can be utilized. A particular concern for space applications is the potential damage to laser performance caused by radiation exposure. While the effects of radiation exposure in diode lasers have been studied extensively, the effect on QCLs, which are fundamentally different from diode lasers, is not well known. We thus present work to quantify the performance of QCLs after exposure to moderate and high levels of radiation from different sources, including protons and gamma rays, to determine the effects of radiation damage.

  16. An extended diffraction tomography method for quantifying structural damage using numerical Green's functions.

    PubMed

    Chan, Eugene; Rose, L R Francis; Wang, Chun H

    2015-05-01

    Existing damage imaging algorithms for detecting and quantifying structural defects, particularly those based on diffraction tomography, assume far-field conditions for the scattered field data. This paper presents a major extension of diffraction tomography that can overcome this limitation and utilises a near-field multi-static data matrix as the input data. This new algorithm, which employs numerical solutions of the dynamic Green's functions, makes it possible to quantitatively image laminar damage even in complex structures for which the dynamic Green's functions are not available analytically. To validate this new method, the numerical Green's functions and the multi-static data matrix for laminar damage in flat and stiffened isotropic plates are first determined using finite element models. Next, these results are time-gated to remove boundary reflections, followed by discrete Fourier transform to obtain the amplitude and phase information for both the baseline (damage-free) and the scattered wave fields. Using these computationally generated results and experimental verification, it is shown that the new imaging algorithm is capable of accurately determining the damage geometry, size and severity for a variety of damage sizes and shapes, including multi-site damage. Some aspects of minimal sensors requirement pertinent to image quality and practical implementation are also briefly discussed. Copyright © 2015 Elsevier B.V. All rights reserved.

  17. The improvement of laser induced damage resistance of optical workpiece surface by hydrodynamic effect polishing

    NASA Astrophysics Data System (ADS)

    Peng, Wenqiang; Guan, Chaoliang; Li, Shengyi; Wang, Zhuo

    2016-10-01

    Surface and subsurface damage in optical element will greatly decrease the laser induced damage threshold (LIDT) in the intense laser optical system. Processing damage on the workpiece surface can be inevitably caused when the material is removed in brittle or plastic mode. As a non-contact polishing technology, hydrodynamic effect polishing (HEP) shows very good performance on generating an ultra-smooth surface without damage. The material is removed by chemisorption between nanoparticle and workpiece surface in the elastic mode in HEP. The subsurface damage and surface scratches can be effectively removed after the polishing process. Meanwhile ultra-smooth surface with atomic level surface roughness can be achieved. To investigate the improvement of LIDT of optical workpiece, polishing experiment was conducted on a magnetorheological finishing (MRF) silica glass sample. AFM measurement results show that all the MRF directional plastic marks have been removed clearly and the root-mean-square (rms) surface roughness has decreased from 0.673nm to 0.177nm after HEP process. Laser induced damage experiment was conducted with laser pulse of 1064nm wavelength and 10ns time width. Compared with the original state, the LEDT of the silica glass sample polished by HEP has increased from 29.78J/cm2 to 45.47J/cm2. It demonstrates that LIDT of optical element treated by HEP can be greatly improved for ultra low surface roughness and nearly defect-free surface/subsurface.

  18. Laser-induced damage and fracture in fused silica vacuum windows

    NASA Astrophysics Data System (ADS)

    Campbell, John H.; Hurst, Patricia A.; Heggins, Dwight D.; Steele, William A.; Bumpas, Stanley E.

    1997-05-01

    Laser induced damage, that initiates catastrophic fracture, has been observed in large, fused silica lenses that also serve as vacuum barriers in high-fluence positions on the Nova and Beamlet lasers. In nearly all cases damage occurs on the vacuum side of the lens. The damage can lead to catastrophic crack growth if the flaw size exceeds the critical flaw size for SiO2. If the elastic stored energy in the lens in high enough, the lens will fracture into many pieces resulting in an implosion. The consequences of such an implosion can be severe, particularly for large vacuum systems. Three parameters control the degree of fracture in the vacuum barrier window: (1) the elastic stored energy, (2) the ratio of the window thickness to flaw depth and (3) secondary crack propagation. Fracture experiments have ben carried our on 15-cm diameter fused silica windows that contain surface flaws caused by laser damage. The results of these experiments, combined with data from window failures on Beamlet and Nova have been sued to develop design criteria for a 'fail-safe' lens. Specifically the window must be made thick enough such that the peak tensile stress is less than 500 psi and the corresponding ratio of the thickness to critical flaw size is less than 6. Under these conditions a properly mounted window, upon failure, will break into only tow pieces and will not implode. One caveat to these design criteria is that the air leak through the window before secondary crack growth occurs. Finite element stress calculations of a window before and immediately following fracture into two pieces show that the elastic stored energy is redistributed if the fragments 'lock' in place and thereby bridge the opening. In such cases, the peak stresses at the flaw site can increase leading to further crack growth.

  19. Soft x-ray free-electron laser induced damage to inorganic scintillators

    DOE PAGES

    Burian, Tomáš; Hájková, Věra; Chalupský, Jaromír; ...

    2015-01-07

    An irreversible response of inorganic scintillators to intense soft x-ray laser radiation was investigated at the FLASH (Free-electron LASer in Hamburg) facility. Three ionic crystals, namely, Ce:YAG (cerium-doped yttrium aluminum garnet), PbWO4 (lead tungstate), and ZnO (zinc oxide), were exposed to single 4.6 nm ultra-short laser pulses of variable pulse energy (up to 12 μJ) under normal incidence conditions with tight focus. Damaged areas produced with various levels of pulse fluences, were analyzed on the surface of irradiated samples using differential interference contrast (DIC) and atomic force microscopy (AFM). The effective beam area of 22.2 ± 2.2 μm2 was determinedmore » by means of the ablation imprints method with the use of poly(methyl methacrylate) - PMMA. Applied to the three inorganic materials, this procedure gave almost the same values of an effective area. The single-shot damage threshold fluence was determined for each of these inorganic materials. The Ce:YAG sample seems to be the most radiation resistant under the given irradiation conditions, its damage threshold was determined to be as high as 660.8 ± 71.2 mJ/cm2. Contrary to that, the PbWO4 sample exhibited the lowest radiation resistance with a threshold fluence of 62.6 ± 11.9 mJ/cm2. The threshold for ZnO was found to be 167.8 ± 30.8 mJ/cm2. Both interaction and material characteristics responsible for the damage threshold difference are discussed in the article.« less

  20. UV-vis spectra as an alternative to the Lowry method for quantify hair damage induced by surfactants.

    PubMed

    Pires-Oliveira, Rafael; Joekes, Inés

    2014-11-01

    It is well known that long term use of shampoo causes damage to human hair. Although the Lowry method has been widely used to quantify hair damage, it is unsuitable to determine this in the presence of some surfactants and there is no other method proposed in literature. In this work, a different method is used to investigate and compare the hair damage induced by four types of surfactants (including three commercial-grade surfactants) and water. Hair samples were immersed in aqueous solution of surfactants under conditions that resemble a shower (38 °C, constant shaking). These solutions become colored with time of contact with hair and its UV-vis spectra were recorded. For comparison, the amount of extracted proteins from hair by sodium dodecyl sulfate (SDS) and by water were estimated by the Lowry method. Additionally, non-pigmented vs. pigmented hair and also sepia melanin were used to understand the washing solution color and their spectra. The results presented herein show that hair degradation is mostly caused by the extraction of proteins, cuticle fragments and melanin granules from hair fiber. It was found that the intensity of solution color varies with the charge density of the surfactants. Furthermore, the intensity of solution color can be correlated to the amount of proteins quantified by the Lowry method as well as to the degree of hair damage. UV-vis spectrum of hair washing solutions is a simple and straightforward method to quantify and compare hair damages induced by different commercial surfactants. Copyright © 2014 Elsevier B.V. All rights reserved.

  1. Optical and electrical properties of indium tin oxide films near their laser damage threshold [Electrical and optical properties of indium tin oxide films under multi-pulse laser irradiation at 1064 nm

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yoo, Jae -Hyuck; Lange, Andrew; Bude, Jeff

    In this paper, we investigated whether the optical and electrical properties of indium tin oxide (ITO) films are degraded under laser irradiation below their laser ablation threshold. While performing multi-pulse laser damage experiments on a single ITO film (4.7 ns, 1064 nm, 10 Hz), we examined the optical and electrical properties in situ. A decrease in reflectance was observed prior to laser damage initiation. However, under sub-damage threshold irradiation, conductivity and reflectance of the film were maintained without measurable degradation. This indicates that ITO films in optoelectronic devices may be operated below their lifetime laser damage threshold without noticeable performancemore » degradation.« less

  2. Optical and electrical properties of indium tin oxide films near their laser damage threshold [Electrical and optical properties of indium tin oxide films under multi-pulse laser irradiation at 1064 nm

    DOE PAGES

    Yoo, Jae -Hyuck; Lange, Andrew; Bude, Jeff; ...

    2017-02-10

    In this paper, we investigated whether the optical and electrical properties of indium tin oxide (ITO) films are degraded under laser irradiation below their laser ablation threshold. While performing multi-pulse laser damage experiments on a single ITO film (4.7 ns, 1064 nm, 10 Hz), we examined the optical and electrical properties in situ. A decrease in reflectance was observed prior to laser damage initiation. However, under sub-damage threshold irradiation, conductivity and reflectance of the film were maintained without measurable degradation. This indicates that ITO films in optoelectronic devices may be operated below their lifetime laser damage threshold without noticeable performancemore » degradation.« less

  3. System and method for laser-based, non-evaporative repair of damage sites in the surfaces of fused silica optics

    DOEpatents

    Adams, John J.; Bolourchi, Masoud; Bude, Jeffrey D.; Guss, Gabriel M.; Jarboe, Jeffery A.; Matthews, Manyalibo J.; Nostrand, Michael C; Wegner, Paul J.

    2016-09-06

    A method for repairing a damage site on a surface of an optical material is disclosed. The method may involve focusing an Infrared (IR) laser beam having a predetermined wavelength, with a predetermined beam power, to a predetermined full width ("F/W") 1/e.sup.2 diameter spot on the damage site. The focused IR laser beam is maintained on the damage site for a predetermined exposure period corresponding to a predetermined acceptable level of downstream intensification. The focused IR laser beam heats the damage site to a predetermined peak temperature, which melts and reflows material at the damage site of the optical material to create a mitigated site.

  4. Ocular damage effects from 1338-nm pulsed laser radiation in a rabbit eye model

    PubMed Central

    Jiao, Luguang; Wang, Jiarui; Jing, Xiaomin; Chen, Hongxia; Yang, Zaifu

    2017-01-01

    The ocular damage effects induced by transitional near-infrared (NIR) lasers have been investigated for years. However, no retinal damage thresholds are determined in a wide interval between 0.65 ms and 80 ms, and a definite relationship between corneal damage threshold and spot size cannot be drawn from existing data points. In this paper, the in-vivo corneal damage thresholds (ED50s) were determined in New Zealand white rabbits for a single 5 ms pulse at the wavelength of 1338 nm for spot sizes from 0.28 mm to 3.55 mm. Meanwhile, the retinal damage threshold for this laser was determined in chinchilla grey rabbits under the condition that the beam was collimated, and the incident corneal spot diameter was 5.0 mm. The corneal ED50s given in terms of the corneal radiant exposure for spot diameters of 0.28, 0.94, 1.91, and 3.55 mm were 70.3, 35.6, 29.6 and 30.3 J/cm2, respectively. The retinal ED50 given in terms of total intraocular energy (TIE) was 0.904 J. The most sensitive ocular tissue to this laser changed from the cornea to retina with the increase of spot size. PMID:28663903

  5. Post-processing of fused silica and its effects on damage resistance to nanosecond pulsed UV lasers.

    PubMed

    Ye, Hui; Li, Yaguo; Zhang, Qinghua; Wang, Wei; Yuan, Zhigang; Wang, Jian; Xu, Qiao

    2016-04-10

    HF-based (hydrofluoric acid) chemical etching has been a widely accepted technique to improve the laser damage performance of fused silica optics and ensure high-power UV laser systems at designed fluence. Etching processes such as acid concentration, composition, material removal amount, and etching state (etching with additional acoustic power or not) may have a great impact on the laser-induced damage threshold (LIDT) of treated sample surfaces. In order to find out the effects of these factors, we utilized the Taguchi method to determine the etching conditions that are helpful in raising the LIDT. Our results show that the most influential factors are concentration of etchants and the material etched away from the viewpoint of damage performance of fused silica optics. In addition, the additional acoustic power (∼0.6  W·cm-2) may not benefit the etching rate and damage performance of fused silica. Moreover, the post-cleaning procedure of etched samples is also important in damage performances of fused silica optics. Different post-cleaning procedures were, thus, experiments on samples treated under the same etching conditions. It is found that the "spraying + rinsing + spraying" cleaning process is favorable to the removal of etching-induced deposits. Residuals on the etched surface are harmful to surface roughness and optical transmission as well as laser damage performance.

  6. Laser damage resistant nematic liquid crystal cell

    NASA Astrophysics Data System (ADS)

    Raszewski, Z.; Piecek, W.; Jaroszewicz, L.; Soms, L.; Marczak, J.; Nowinowski-Kruszelnicki, E.; Perkowski, P.; Kedzierski, J.; Miszczyk, E.; Olifierczuk, M.; Morawiak, P.; Mazur, R.

    2013-08-01

    There exists a problem in diagnostics of a dense plasma (so-called Thomson diagnostics). For this purpose, the plasma is illuminated by series of high energy laser pulses. Such pulses are generated by several independent lasers operating sequentially, and these pulses are to be directed along an exactly the same optical path. In this case, the energy of each separate pulse is as large as 3 J, so it is impossible to generate a burst of such pulses by a single laser. In this situation, several independent lasers have to be used. To form optical path with λ = 1.064 μm and absolute value of the energy of laser pulse through of 3 J, a special refractive index matched twisted Nematic Liquid Crystal Cell (NLCC) of type LCNP2 with switching on time τON smaller than 5 μs might be applied. High laser damage resistance of NLCC and short τON can be fulfilled by preparation of liquid crystal cells with Liquid Crystal Mixture (LCM), well tuned to twisted nematic electro-optical effect, and well tuned all optical interfaces (Air - Antireflection - Quartz Plate - Electrode - Blocking Film - Aligning Layer - LCM - Aligning Layer - Blocking Film - Electrode - Quartz Plate - Antireflection - Air). In such LCNP2 cell, the transmission is higher than 97% at λ = 1.064 μm, as it is presented by Gooch and Tarry [J. Phys. D: Appl. Phys. 8, 1575 (1975)]. The safe laser density energy is about 0.6 J/cm2 for a train of laser pulses (λ = 1.064 μm, pulse duration 10 ns FWHM, pulse repetition rate 100 pps, train duration 10 s), so the area of liquid crystal cell tolerating 3 J through it shall be as large as 5 cm2. Due to the presence of two blocking film layers between electrodes, LCNP2 can be driven by high voltages. Switching on time smaller than τON = 5 μs was obtained under 200 V switching voltage.

  7. Laser vibrometry for guided wave propagation phenomena visualisation and damage detection

    NASA Astrophysics Data System (ADS)

    Malinowski, Pawel; Wandowski, Tomasz; Kudela, Pawel; Ostachowicz, Wieslaw

    2010-05-01

    This paper presents research on the damage localization method. The method is based on guided wave propagation phenomena. The investigation was focused on application of this method to monitor the condition of structural elements such as aluminium or composite panels. These elements are commonly used in aerospace industry and it is crucial to provide a methodology to determine their condition, in order to prevent from unexpected and dangerous collapse of a structure. Propagating waves interact with cracks, notches, rivets, thickness changes, stiffeners and other discontinuities present in structural elements. It means that registering these waves one can obtain information about the structure condition—whether it is damaged or not. Furthermore these methods can be applied not only to aerospace structures but also to wind turbine blades and pipelines. In reported investigation piezoelectric transducer was used to excite guided waves in considered panel. Measurement of the wave field was realized using laser scanning vibrometer that registered the velocity responses at a defined points belonging to a defined mesh. Mesh spacing was investigated in order to ensure fine wave propagation visualisation. Firstly, wave propagation in pristine specimen was investigated. Secondly, artificial damage was introduced to the specimen. Finally, wave interaction with damage was visualised and conclusions regarding potentials of application of laser vibrometer for damage detection were drawn. All the processing was made with the developed MATLAB procedures.

  8. Thin film contamination effects on laser-induced damage of fused silica surfaces at 355 nm

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Burnham, A. K.; Cordillot, C.; Fornier, A.

    1998-07-28

    Fused silica windows were artificially contaminated to estimate the resistance of target chamber debris shields against laser damage during NIF operation. Uniform contamination thin films (1 to 5 nm thick) were prepared by sputtering various materials (Au, Al, Cu, and B 4C). The loss of transmission of the samples was first measured. They were then tested at 355 nm in air with an 8-ns Nd:YAG laser. The damage morphologies were characterized by Nomarski optical microscopy and SEM. Both theory and experiments showed that metal contamination for films as thin as 1 nm leads to a substantial loss of transmission. Themore » laser damage resistance dropped very uniformly across the entire surface (e.g. 6 J/cm 2 for 5 nm of Cu). The damage morphology characterization showed that contrary to clean silica, metal coated samples did not produce pits on the surface. B 4C coated silica, on the other hand, led to a higher density of such damage pits. A model for light absorption in the thin film was coupled with a simple heat deposition and diffusion model to perform preliminary theoretical estimates of damage thresholds. The estimates of the loss due to light absorption and reflection pointed out significant .differences between metals (e.g. Al and Au). The damage threshold predictions were in qualitative agreement with experimental measurements.« less

  9. Physical analysis on laser-induced cerebral damage

    NASA Astrophysics Data System (ADS)

    Luo, Xiaosen; Liu, Jiangang; Tao, Chunkan; Lan, Xiufeng; Cao, Lingyan; Pan, Weimin; Shen, Zhonghua; Lu, Jian; Ni, Xiaowu

    2005-01-01

    Experimental investigation on cerebral damage of adult SD rats induced by 532nm CW laser was performed. Tissue heat conductive equation was set up based on two-layered structure model. Finite difference algorithm was utilized to numerically simulate the temperature distribution in the brain tissue. Allowing for tissue response to temperature variation, free boundary model was used to discuss tissue thermal coagulation formation in brain. Experimental observations show that thermal coagulation and necrosis can be caused due to laser light absorption. The result of the calculation shows that the process of the thermal coagulation of the given mode comprises two stages: fast and slow. At the first stage, necrosis domain grows fast. Then necrosis domain growth becomes slower because of the competition between the heat diffusion into the surrounding undamaged tissue and the heat dissipation caused by blood perfusion. At the center of coagulation area no neuron was observed and at the transitional zone few nervous cells were seen by microscope. The research can provide reference data for developing clinical therapy of some kind of encephalic diseases by using 532nm laser, and for making cerebral infarction models in animal experiment.

  10. Photothermal therapy to damage PC3 cancer cells: in vitro studies of a pulsed laser (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Zamora-Romero, Noe; Aguilar, Guillermo; Devia-Cruz, Luis F.; Banks, Darren; Zhang, Bin; Halaney, David L.

    2017-02-01

    Laser-nanoparticles interactions have been widely used for several years. In biomedicine, several in vitro and in vivo experiments have shown promising results for the detection and treatment of cancer. One of the techniques of interest to us, is the nanoparticle-assisted photothermal therapy (PTT), which consists of irradiating cancer cells incubated with nanoparticles with either a pulsed or continuous (cw) laser in order to damage the cells. However, there is still a debate over which type of laser is most effective for PTT for cancer treatment. On the one hand, cw lasers are minimally invasive and can be used for both detection and treatment of tumors. On the other hand, pulsed lasers offer great spatial precision and can deposit higher energy fluences than cw lasers, making them very efficient for inducing cavitation to damage cancer cells and tumors mechanically. The aim of this study is to investigate whether simultaneous application of cw and pulsed laser could offer a synergetic enhancement of PTT efficacy to damage cancer cells in vitro, compared to either laser applied individually. PTT efficacy is evaluated through cell viability tests following the irradiation of prostate cancer (PC3) cells incubated with gold nanorods (5.7 X10 10 p/ml). By irradiating the PC3-nanorod solution with the cw laser at 808 nm for 60 seconds, the temperature increases from 37.5 to 45°C, which damages some cancer cells via the heat shock response within the cells, and also could increase their sensitivity to the mechanical stress caused by the shock wave generated from inducing cavitation in the solution by the pulsed laser irradiation.

  11. Laser megajoule 1.06-μm mirror production with very high laser damage threshold

    NASA Astrophysics Data System (ADS)

    Pinot, B.; Leplan, Herve; Houbre, Francois; Lavastre, Eric; Poncetta, Jean-Christophe; Chabassier, Genevieve

    2002-03-01

    As part of the LMJ (Laser Megajoule) program, CEA is building the LIL laser with full size optics and LMJ requirements. SAGEM has been selected as the supplier of large optical components and coatings with very high laser- induced damage threshold. Including spare parts, about 100 mirrors 610*430 mm2 with LIDT-3ns>25 J/cm2 have to be produced. Using a 5 m3 vacuum chamber and the 100 J/cm2 mirror coating process developed at CEA-LETI, with Hafnium and SiO2 materials, we are now typically in a serial production phase. To date, about thirty mirrors have been delivered. This paper focuses on the acceptance tests performed after coating, at SAGEM then CEA: LIDT measurement and Raster-Scan on samples; reflectance mapping on CEA automatic photometer; reflected wavefront deformation with \

  12. Laser damage testing of optical components under cryogenic conditions

    NASA Astrophysics Data System (ADS)

    Oulehla, Jindrich; Pokorný, Pavel; Lazar, Josef

    2012-11-01

    In this contribution we present a technology for deposition and testing of interference coatings for optical components designed to operate in power pulsed lasers. The aim of the technology is to prepare components for high power laser facilities such as ELI (Extreme Light Infrastructure) or HiLASE. ELI is a part of the European plan to build a new generation of large research facilities selected by the European Strategy Forum for Research Infrastructures (ESFRI). These facilities rely on the use of diode pumped solid state lasers (DPSSL). The choice of the material for the lasers' optical components is critical. Some of the most important properties include the ability to be antireflection and high reflection coated to reduce the energy losses and increase the overall efficiency. As large amounts of heat need to be dissipated during laser operation, cryogenic cooling is necessary. The conducted experiments served as preliminary tests of laser damage threshold measurement methodology that we plan to use in the future. We designed a special apparatus consisting of a vacuum chamber and a cooling system. The samples were placed into the vacuum chamber which was evacuated and then the samples were cooled down to approximately 120K and illuminated by a pulsed laser. Pulse duration was in the nanosecond region. Multiple test sites on the sample's surface were used for different laser pulse energies. We used optical and electron microscopy and spectrophotometer measurements for coating investigation after the conducted experiments.

  13. Laser damage testing of optical components under cryogenic conditions

    NASA Astrophysics Data System (ADS)

    Oulehla, Jindřich; Pokorný, Pavel; Lazar, Josef

    2012-01-01

    In this contribution we present a technology for deposition and testing of interference coatings for optical components designed to operate in power pulsed lasers. The aim of the technology is to prepare components for high power laser facilities such as ELI (Extreme Light Infrastructure) or HiLASE. ELI is a part of the Eropean plan to build a new generation of large research facilities selected by the the Eropean Strategy Forum for Research Infrastructures (ESFRI). These facilities rely on the use of diode pumped solid state lasers (DPSSL). The choice of the material or the lasers' optical components is critical. Some of the most important properties include the ability to be antireflection and high reflection coated to reduce the energy losses and increase the overall efficiency. As large amounts of hear need to be dissipated during laser operation, cryogenic cooling is necessary. The conducted experiments served as preliminary tests of laser damage threshold measurement methodology that we plan to use in the future. We designed a special apparatus consistion of a vacuum chamber an a cooling system. The samples were placed into the vacuum chamber which was evacuated and them the samples were cooled down to approximately 120K and illuminated by a pulsed laser. Pulse duration was in the nanosecond region. Multiple test sites on the sample's surface were used for different laser pulse energies. We used optical and electron microscopy and spectrophotometer measurements for coating investigation after the conducted experiments.

  14. Multiple pulse nanosecond laser induced damage threshold on hybrid mirrors

    NASA Astrophysics Data System (ADS)

    Vanda, Jan; Muresan, Mihai-George; Bilek, Vojtech; Sebek, Matej; Hanus, Martin; Lucianetti, Antonio; Rostohar, Danijela; Mocek, Tomas; Škoda, Václav

    2017-11-01

    So-called hybrid mirrors, consisting of broadband metallic surface coated with dielectric reflector designed for specific wavelength, becoming more important with progressing development of broadband mid-IR sources realized using parametric down conversion system. Multiple pulse nanosecond laser induced damage on such mirrors was tested by method s-on-1, where s stands for various numbers of pulses. We show difference in damage threshold between common protected silver mirrors and hybrid silver mirrors prepared by PVD technique and their variants prepared by IAD. Keywords: LIDT,

  15. Combined advanced finishing and UV laser conditioning process for producing damage resistant optics

    DOEpatents

    Menapace, Joseph A.; Peterson, John E.; Penetrante, Bernardino M.; Miller, Philip E.; Parham, Thomas G.; Nichols, Michael A.

    2005-07-26

    A method for reducing the density of sites on the surface of fused silica optics that are prone to the initiation of laser-induced damage, resulting in optics which have far fewer catastrophic defects, and are better capable of resisting optical deterioration upon exposure to a high-power laser beam.

  16. Analysis of thermal damage in vocal cords for the prevention of collateral laser treatment effects

    NASA Astrophysics Data System (ADS)

    Fanjul Vélez, Félix; Luis Arce-Diego, José; del Barrio Fernández, Ángela; Borragán Torre, Alfonso

    2007-05-01

    The importance of vocal cords for the interaction with the world around is obviously known. Vocal cords disorders can be divided mainly into three categories: difficulty of movement of one or both vocal folds, lesion formation on them, and difficulty or lack of mucosal wave movement. In this last case, a laser heating treatment can be useful in order to improve tissue vibration. However, thermal damage should be considered to adjust laser parameters and so to prevent irreversible harmful effects to the patient. in this work, an analysis of thermal damage in vocal folds is proposed. Firstly thermo-optical laser-tissue interaction is studied, by means of a RTT (Radiation Transfer Theory) model solved with a Monte Carlo approach for the optical propagation of radiation, and a bio-heat equation, with a finite difference numerical method based solution, taking into account blood perfusion and boundary effects, for the thermal distribution. The spatial-temporal temperature distributions are obtained for two widely used lasers, Nd:YAG (1064 nm) and KTP (532 nm). From these data, an Arrhenius thermal damage analysis allows a prediction of possible laser treatment harmful effects on vocal cords that could cause scar formation or tissue burn. Different source powers and exposition times are considered, in such a way that an approximation of adequate wavelength, power and duration is achieved, in order to implement an efficient and safe laser treatment.

  17. Proximal fiber tip damage during Holmium:YAG and thulium fiber laser ablation of kidney stones

    NASA Astrophysics Data System (ADS)

    Wilson, Christopher R.; Hardy, Luke A.; Irby, Pierce B.; Fried, Nathaniel M.

    2016-02-01

    The Thulium fiber laser (TFL) is being studied as an alternative to Holmium:YAG laser for lithotripsy. TFL beam originates within an 18-μm-core thulium doped silica fiber, and its near single mode, Gaussian beam profile enables transmission of higher laser power through smaller fibers than possible during Holmium laser lithotripsy. This study examines whether TFL beam profile also reduces proximal fiber tip damage compared to Holmium laser multimodal beam. TFL beam at wavelength of 1908 nm was coupled into 105-μm-core silica fibers, with 35-mJ energy, 500-μs pulse duration, and pulse rates of 50-500 Hz. For each pulse rate, 500,000 pulses were delivered. Magnified images of proximal fiber surfaces were taken before and after each trial. For comparison, 20 single-use, 270-μm-core fibers were collected after clinical Holmium laser lithotripsy procedures using standard settings (600 mJ, 350 μs, 6 Hz). Total laser energy, number of laser pulses, and laser irradiation time were recorded, and fibers were rated for damage. For TFL studies, output power was stable, and no proximal fiber damage was observed after delivery of 500,000 pulses at settings up to 35 mJ, 500 Hz, and 17.5 W average power. In contrast, confocal microscopy images of fiber tips after Holmium lithotripsy showed proximal fiber tip degradation in all 20 fibers. The proximal fiber tip of a 105-μm-core fiber transmitted 17.5 W of TFL power without degradation, compared to degradation of 270-μm-core fibers after transmission of 3.6 W of Holmium laser power. The smaller and more uniform TFL beam profile may improve fiber lifetime, and potentially reduce costs for the surgical disposables as well.

  18. Nondestructive monitoring damage in composites using scanning laser acoustic microscopy

    NASA Technical Reports Server (NTRS)

    Wey, A. C.; Kessler, L. W.; Dos Reis, H. L. M.

    1992-01-01

    Several Nicalon fiber reinforced LAS (lithium alumino-silicate) glass matrix composites were tested to study the relation between the residual strength and the different amounts of damage. The samples were fatigued by four-point cyclic loading at a 5 Hz rate at 500 C for a different number of cycles. 10 MHz scanning laser acoustic microscope (SLAM) images were taken to monitor damage on the samples. Our SLAM results indicate that there were defects already existing throughout the sample before fatigue, and the resultant damage pattern from fatigue could be related to the initial defect distribution in the sample. Finally, the fatigued samples were fractured and the residual strength data could not be explained by the cyclic fatigue alone. Rather, the damage patterns evident in the SLAM images were needed to explain the scatter in the data. The results show that SLAM is useful in nondestructively monitoring damage and estimating residual strength of fatigued ceramic composites.

  19. Experimental evaluation of a new system for laser tissue welding applied on damaged lungs.

    PubMed

    Schiavon, Marco; Marulli, Giuseppe; Zuin, Andrea; Lunardi, Francesca; Villoresi, Paolo; Bonora, Stefano; Calabrese, Fiorella; Rea, Federico

    2013-05-01

    Alveolar air leaks represent a challenging problem in thoracic surgery, leading to increased patient morbidity and prolonged hospitalization. Several methods have been used, but no ideal technique exists yet. We investigated the lung-sealing capacity of an experimental kit for laser tissue welding. The kit is composed of a semiconductor laser system applied on a protein substrate associated with a chromophore that increases absorption. In vitro tests on porcine lung tissue were done to define ideal laser parameters (power 100 Å, frequency 50 Hz, pulse duration 400 µs) and protein substrate dilution (50%). For in vivo tests, through a left thoracotomy, 14 pigs received two different lung damages: a linear incision and a circular incision. Protein substrate applied on damaged areas was treated with laser to obtain a layer that reconstituted the integrity of the visceral pleura. Air leaks were intraoperatively evaluated by water submersion test with an airway pressure of 20 cmH2O. Animals were sacrificed at postoperative days 0 and 7 to study early and late pathological features. After applying laser treatment, no air leaks were seen in all proofs except in 2 cases in which a second application was required. At time 0, pathological damage mostly consisted of superficial alveolar necrotic tissue covered by protein membrane. At time 7, a complete recovery of lung lesions by fibrous scar with slight inflammatory reaction of adjacent lung tissue was seen. This experimental study demonstrated the effectiveness of laser tissue welding applied to seal air leaks after lung surgery. Further studies are needed to verify acceptability for human application.

  20. Damage Considerations of a Flexible Micro Air Vehicle Wing Using 3-D Laser Vibrometry

    DTIC Science & Technology

    2007-06-01

    AIR VEHICLE WING USING 3-D LASER VIBROMETRY THESIS Leo L. Mendoza Jr., ENS, USN AFIT/GAE/ENY/07-J13 DEPARTMENT OF THE AIR FORCE AIR ...3-D LASER VIBROMETRY THESIS Presented to the Faculty Department of Aeronautical and Astronautical Engineering Air Force...DISTRIBUTION UNLIMITED AFIT/GAE/ENY/07-J13 DAMAGE CONSIDERATIONS OF A FLEXIBLE MICRO AIR VEHICLE WING USING 3-D LASER VIBROMETRY

  1. The role of defects in laser-induced modifications of silica coatings and fused silica using picosecond pulses at 1053 nm: I Damage morphology

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Laurence, T. A.; Ly, S.; Shen, N.

    Laser-induced damage with ps pulse widths straddles the transition from intrinsic, multi-photon ionization and avalanche ionization-based ablation with fs pulses to defect-dominated, thermal-based damage with ns pulses. We investigated the morphology of damage for fused silica and silica coatings between 1 ps and 60 ps at 1053 nm. Using calibrated laser-induced damage experiments, in situ imaging, and high-resolution optical microscopy, atomic force microscopy, and scanning electron microscopy, we show that defects play an important role in laser-induced damage down to 1 ps. Three types of damage are observed: ablation craters, ultra-high density pits, and smooth, circular depressions with central pits.more » For 10 ps and longer, the smooth, circular depressions limit the damage performance of fused silica and silica coatings. The observed high-density pits and material removal down to 3 ps indicate that variations in surface properties limit the laser-induced damage onset to a greater extent than expected below 60 ps. Below 3 ps, damage craters are smoother although there is still evidence as seen by AFM of inhomogeneous laser-induced damage response very near the damage onset. These results show that modeling the damage onset only as a function of pulse width does not capture the convoluted processes leading to laser induced damage with ps pulses. It is necessary to account for the effects of defects on the processes leading to laser-induced damage. In conclusion, the effects of isolated defects or inhomogeneities are most pronounced above 3 ps but are still discernible and possibly important down to the shortest pulse width investigated here.« less

  2. The role of defects in laser-induced modifications of silica coatings and fused silica using picosecond pulses at 1053 nm: I Damage morphology

    DOE PAGES

    Laurence, T. A.; Ly, S.; Shen, N.; ...

    2017-06-22

    Laser-induced damage with ps pulse widths straddles the transition from intrinsic, multi-photon ionization and avalanche ionization-based ablation with fs pulses to defect-dominated, thermal-based damage with ns pulses. We investigated the morphology of damage for fused silica and silica coatings between 1 ps and 60 ps at 1053 nm. Using calibrated laser-induced damage experiments, in situ imaging, and high-resolution optical microscopy, atomic force microscopy, and scanning electron microscopy, we show that defects play an important role in laser-induced damage down to 1 ps. Three types of damage are observed: ablation craters, ultra-high density pits, and smooth, circular depressions with central pits.more » For 10 ps and longer, the smooth, circular depressions limit the damage performance of fused silica and silica coatings. The observed high-density pits and material removal down to 3 ps indicate that variations in surface properties limit the laser-induced damage onset to a greater extent than expected below 60 ps. Below 3 ps, damage craters are smoother although there is still evidence as seen by AFM of inhomogeneous laser-induced damage response very near the damage onset. These results show that modeling the damage onset only as a function of pulse width does not capture the convoluted processes leading to laser induced damage with ps pulses. It is necessary to account for the effects of defects on the processes leading to laser-induced damage. In conclusion, the effects of isolated defects or inhomogeneities are most pronounced above 3 ps but are still discernible and possibly important down to the shortest pulse width investigated here.« less

  3. Increase of bulk optical damage threshold fluences of KDP crystals by laser irradiation and heat treatment

    DOEpatents

    Swain, J.E.; Stokowski, S.E.; Milam, D.; Kennedy, G.C.; Rainer, F.

    1982-07-07

    The bulk optical damage threshold fluence of potassium dihydrogen phosphate (KDP) crystals is increased by irradiating the crystals with laser pulses of duration 1 to 20 nanoseconds of increasing fluence, below the optical damage threshold fluence for untreated crystals, or by baking the crystals for times of the order of 24 hours at temperatures of 110 to 165/sup 0/C, or by a combination of laser irradiation and baking.

  4. Mechanism for atmosphere dependence of laser damage morphology in HfO2/SiO2 high reflective films

    NASA Astrophysics Data System (ADS)

    Pu, Yunti; Ma, Ping; Chen, Songlin; Zhu, Jiliang; Wang, Gang; Pan, Feng; Sun, Ping; Zhu, Xiaohong; Zhu, Jianguo; Xiao, Dingquan

    2012-07-01

    We show in this paper single-shot and multi-shot laser-induced damage thresholds (LIDTs) of HfO2/SiO2 high reflective films (the reflectance = 99.9%) are affected by the presence of a water layer absorbed on the surface of the porous films. When the water layer was removed with the process of pumping, the single-shot LIDT measured in vacuum dropped to ˜48% of that measured in air, while the multi-shot LIDT in vacuum dropped to ˜47% of its atmospheric value for the high reflective films. Typical damage micrographs of the films in air and in vacuum were obtained, showing distinct damage morphologies. Such atmosphere dependence of the laser damage morphology was found to originate from that formation of a water layer on the surface of porous films could cause an increase of horizontal thermal conductivity and a reduction of vertical thermal conductivity. Moreover, laser-induced periodic ripple damages in air were found in the SiO2 layer from the micrographs. A model of deformation kinematics was used to illustrate the occurrence of the periodic ripple damage, showing that it could be attributed to a contraction of the HfO2 layer under irradiation by the 5-ns laser pulses in air.

  5. Quantifying the statistical complexity of low-frequency fluctuations in semiconductor lasers with optical feedback

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tiana-Alsina, J.; Torrent, M. C.; Masoller, C.

    Low-frequency fluctuations (LFFs) represent a dynamical instability that occurs in semiconductor lasers when they are operated near the lasing threshold and subject to moderate optical feedback. LFFs consist of sudden power dropouts followed by gradual, stepwise recoveries. We analyze experimental time series of intensity dropouts and quantify the complexity of the underlying dynamics employing two tools from information theory, namely, Shannon's entropy and the Martin, Plastino, and Rosso statistical complexity measure. These measures are computed using a method based on ordinal patterns, by which the relative length and ordering of consecutive interdropout intervals (i.e., the time intervals between consecutive intensitymore » dropouts) are analyzed, disregarding the precise timing of the dropouts and the absolute durations of the interdropout intervals. We show that this methodology is suitable for quantifying subtle characteristics of the LFFs, and in particular the transition to fully developed chaos that takes place when the laser's pump current is increased. Our method shows that the statistical complexity of the laser does not increase continuously with the pump current, but levels off before reaching the coherence collapse regime. This behavior coincides with that of the first- and second-order correlations of the interdropout intervals, suggesting that these correlations, and not the chaotic behavior, are what determine the level of complexity of the laser's dynamics. These results hold for two different dynamical regimes, namely, sustained LFFs and coexistence between LFFs and steady-state emission.« less

  6. Geometric identification and damage detection of structural elements by terrestrial laser scanner

    NASA Astrophysics Data System (ADS)

    Hou, Tsung-Chin; Liu, Yu-Wei; Su, Yu-Min

    2016-04-01

    In recent years, three-dimensional (3D) terrestrial laser scanning technologies with higher precision and higher capability are developing rapidly. The growing maturity of laser scanning has gradually approached the required precision as those have been provided by traditional structural monitoring technologies. Together with widely available fast computation for massive point cloud data processing, 3D laser scanning can serve as an efficient structural monitoring alternative for civil engineering communities. Currently most research efforts have focused on integrating/calculating the measured multi-station point cloud data, as well as modeling/establishing the 3D meshes of the scanned objects. Very little attention has been spent on extracting the information related to health conditions and mechanical states of structures. In this study, an automated numerical approach that integrates various existing algorithms for geometric identification and damage detection of structural elements were established. Specifically, adaptive meshes were employed for classifying the point cloud data of the structural elements, and detecting the associated damages from the calculated eigenvalues in each area of the structural element. Furthermore, kd-tree was used to enhance the searching efficiency of plane fitting which were later used for identifying the boundaries of structural elements. The results of geometric identification were compared with M3C2 algorithm provided by CloudCompare, as well as validated by LVDT measurements of full-scale reinforced concrete beams tested in laboratory. It shows that 3D laser scanning, through the established processing approaches of the point cloud data, can offer a rapid, nondestructive, remote, and accurate solution for geometric identification and damage detection of structural elements.

  7. Laser induced damage in optical materials: twelfth ASTM symposium.

    PubMed

    Bennett, H E; Glass, A J; Guenther, A H; Newnam, B

    1981-09-01

    The twelfth annual Symposium on Optical Materials for High Power Lasers (Boulder Damage Symposium) was held at the National Bureau of Standards in Boulder, Colorado, 30 Sept.-l Oct., 1980. The symposium was held under the auspices of ASTM Committee F-l, Subcommittee on Laser Standards, with the joint sponsorship of NBS, the Defense Advanced Research Projects Agency, the Department of Energy, the Office of Naval Research, and the Air Force Office of Scientific research. Over 150 scientists attended the symposium, including representatives of the United Kingdom, France, Japan, and West Germany. The symposium was divided into sessions concerning materials and measurements, mirrors and surfaces, thin films, and finally fundamental mechanisms. As in previous years, the emphasis of the papers presented at the symposium was directed toward new frontiers and new developments. Particular emphasis was given to materials for high power systems. The wavelength range of prime interest was from 10.6 microm to the UV region. Highlights included surface characterization, thin film-substrate boundaries, and advances in fundamental laser-matter threshold interactions and mechanisms. The scaling of damage thresholds with pulse duration, focal area, and wavelength was discussed in detail. Harold E. Bennett of the Naval Weapons Center, Alexander J. Glass of the Lawrence Livermore National Laboratory, Arthur H. Guenther of the Air Force Weapons Laboratory, and Brian E. Newnam of the Los Alamos National Laboratory were cochairmen of the symposium. The thirteenth annual symposium is scheduled for 17-18 Nov. 1981 at the National Bureau of Standards, Boulder, Colorado.

  8. Laser induced damage in optical materials: 8th ASTM symposium.

    PubMed

    Glass, A J; Guenther, A H

    1977-05-01

    The Eighth Annual Symposium on Optical Materials for High Power Lasers (Boulder Damage Symposium) was hosted by the National Bureau of Standards in Boulder, Colorado, from 13 to 15 July 1976. The Symposium was held under the auspices of ASTM Committee F-1, Subcommittee on Laser Standards, with the joint sponsorship of NBS, the Defense Advanced Research Project Agency, the Energy Research and Development Administration, and the Office of Naval Research. About 160 scientists attended the Symposium, including representatives of the United Kingdom, France, Canada, and Brazil. The Symposium was divided into five half-day sessions concerning Bulk Material Properties and Thermal Behavior, Mirrors and Surfaces, Thin Film Properties, Thin Film Damage, and Scaling Laws and Fundamental Mechanisms. As in previous years, the emphasis of the papers presented at the Symposium was directed toward new frontiers and new developments. Particular emphasis was given to new materials for use at 10.6 microm in mirror substrates, windo s, and coatings. New techniques in film deposition and advances in diamond-turning of optics were described. The scaling of damage thresholds with pulse duration, focal area, and wavelength were discussed. Alexander J. Glass of Lawrence Livermore Laboratory and Arthur H. Guenther of the Air Force Weapons Laboratory were co-chairpersons of the Symposium. The Ninth Annual Symposium is scheduled for 4-6 October 1977 at the National Bureau of Standards, Boulder, Colorado.

  9. Radiation damage to amorphous carbon thin films irradiated by multiple 46.9 nm laser shots below the single-shot damage threshold

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Juha, L.; Hajkova, V.; Vorlicek, V.

    2009-05-01

    High-surface-quality amorphous carbon (a-C) optical coatings with a thickness of 45 nm, deposited by magnetron sputtering on a silicon substrate, were irradiated by the focused beam of capillary-discharge Ne-like Ar extreme ultraviolet laser (CDL=capillary-discharge laser; XUV=extreme ultraviolet, i.e., wavelengths below 100 nm). The laser wavelength and pulse duration were 46.9 nm and 1.7 ns, respectively. The laser beam was focused onto the sample surface by a spherical Sc/Si multilayer mirror with a total reflectivity of about 30%. The laser pulse energy was varied from 0.4 to 40 muJ on the sample surface. The irradiation was carried out at five fluencemore » levels between 0.1 and 10 J/cm{sup 2}, accumulating five different series of shots, i.e., 1, 5, 10, 20, and 40. The damage to the a-C thin layer was investigated by atomic force microscopy (AFM) and Nomarski differential interference contrast (DIC) optical microscopy. The dependence of the single-shot-damaged area on pulse energy makes it possible to determine a beam spot diameter in the focus. Its value was found to be equal to 23.3+-3.0 mum using AFM data, assuming the beam to have a Gaussian profile. Such a plot can also be used for a determination of single-shot damage threshold in a-C. A single-shot threshold value of 1.1 J/cm{sup 2} was found. Investigating the consequences of the multiple-shot exposure, it has been found that an accumulation of 10, 20, and 40 shots at a fluence of 0.5 J/cm{sup 2}, i.e., below the single-shot damage threshold, causes irreversible changes of thin a-C layers, which can be registered by both the AFM and the DIC microscopy. In the center of the damaged area, AFM shows a-C removal to a maximum depth of 0.3, 1.2, and 1.5 nm for 10-, 20- and 40-shot exposure, respectively. Raman microprobe analysis does not indicate any change in the structure of the remaining a-C material. The erosive behavior reported here contrasts with the material expansion observed earlier [L. Juha

  10. Simulation of Laser Induced Thermal Damage in Nd:YVO4 Crystals

    NASA Astrophysics Data System (ADS)

    Nagi, Richie

    Neodymium-doped yttrium orthovanadate (Nd:YVO4) is a commonly used gain medium in Diode Pumped Solid State (DPSS) lasers, but high heat loading of Nd:YVO4 at high pump powers (≥ 5 W) leads to thermal distortions and crystal fracture, which limits the utility of Nd:YVO 4 for high power applications. In this thesis, a Nd:YVO4 crystal suffered thermal damage during experiments for investigating the optical gain characteristics of the crystal. This thesis examines the thermal damage mechanisms in detail. Principally, laser induced melting, as well as laser induced thermal stress fracture were studied, all in the absence of stimulated emission in the crystal. The optical system for coupling the pump laser light into the crystal was first simulated in Zemax, an optical design software, and the simulations were then compared to the experimental coupling efficiency results, which were found to be in agreement. The simulations for the laser coupling system were then used in conjunction with LASCAD, a finite element analysis software, to obtain the temperatures inside the crystal, as a function of optical power coupled into the crystal. The temperature simulations were then compared to the experimental results, which were in excellent agreement, and the temperature simulations were then generalized to other crystal geometries and Nd doping levels. Zemax and LASCAD were also used to simulate the thermal stress in the crystal as a function of the coupled optical power, and the simulations were compared to experiments, both of which were found to be in agreement. The thermal stress simulations were then generalized to different crystal geometries and Nd doping levels as well.

  11. Sensor-based laser ablation for tissue specific cutting: an experimental study.

    PubMed

    Rupprecht, Stephan; Tangermann-Gerk, Katja; Wiltfang, Joerg; Neukam, Friedrich Wilhelm; Schlegel, Andreas

    2004-01-01

    The interaction of laser light and tissue causes measurable phenomenons. These phenomenons can be quantified and used to control the laser drilling within a feedback system. Ten halves of dissected minipig jaws were treated with an Er:YAG laser system controlled via a feedback system. Sensor outputs were recorded and analyzed while osteotomy was done. The relative depth of laser ablation was calculated by 3D computed tomography and evaluated histologically. The detected signals caused by the laser-tissue interaction changed their character in a dramatic way after passing the cortical bone layer. The radiological evaluation of 98 laser-ablated holes in the ten halves showed no deeper ablation beyond the cortical layer (mean values: 97.8%). Histologically, no physical damage to the alveolar nerve bundle was proved. The feedback system to control the laser drilling was working exactly for cortical ablation of the bone based on the evaluation of detected and quantified phenomenon related to the laser-tissue interaction.

  12. Surface damage of thin AlN films with increased oxygen content by nanosecond and femtosecond laser pulses

    NASA Astrophysics Data System (ADS)

    Gruzdev, Vitaly; Salakhutdinov, Ildar; Chen, J. K.; Danylyuk, Yuriy; McCullen, Erik; Auner, Gregory

    2009-10-01

    AlN films deposited on sapphire substrates were damaged by single UV nanosecond (at 248 nm) and IR femtosecond (at 775 nm) laser pulses in air at normal pressure. The films had high (27-35 atomic %) concentration of oxygen introduced into thin surface layer (5-10 nm thickness). We measured damage threshold and studied morphology of the damage sites with atomic force and Nomarski optical microscopes with the objective to determine a correlation between damage processes and oxygen content. The damage produced by nanosecond pulses was accompanied by significant thermal effects with evident signatures of melting, chemical modification of the film surface, and specific redistribution of micro-defect rings around the damage spots. The nanosecond-damage threshold exhibited pronounced increase with increase of the oxygen content. In contrast to that, the femtosecond pulses produced damage without any signs of thermal, thermo-mechanical or chemical effects. No correlation between femtosecond-damage threshold and oxygen content as well as presence of defects within the laser-damage spot was found. We discuss the influence of the oxygen contamination on film properties and related mechanisms responsible for the specific damage effects and morphology of the damage sites observed in the experiments.

  13. Interaction of 1.319 μm laser with skin: an optical-thermal-damage model and experimental validation

    NASA Astrophysics Data System (ADS)

    Jiao, Luguang; Yang, Zaifu; Wang, Jiarui

    2014-09-01

    With the widespread use of high-power laser systems operating within the wavelength region of approximately 1.3 to 1.4 μm, it becomes very necessary to refine the laser safety guidelines setting the exposure limits for the eye and skin. In this paper, an optical-thermal-damage model was developed to simulate laser propagation, energy deposition, heat transfer and thermal damage in the skin for 1.319 μm laser irradiation. Meanwhile, an experiment was also conducted in vitro to measure the tempreture history of a porcine skin specimen irradiated by a 1.319 μm laser. Predictions from the model included light distribution in the skin, temperature response and thermal damge level of the tissue. It was shown that the light distribution region was much larger than that of the incident laser at the wavelength of 1.319 μm, and the maximum value of the fluence rate located on the interior region of the skin, not on the surface. By comparing the calculated temperature curve with the experimentally recorded temperautre data, good agreement was shown betweeen them, which validated the numerical model. The model also indicated that the damage integral changed little when the temperature of skin tissue was lower than about 55 °C, after that, the integral increased rapidly and denatunation of the tissue would occur. Based on this model, we can further explore the damage mechanisms and trends for the skin and eye within the wavelength region of 1.3 μm to 1.4 μm, incorporating with in vivo experimental investigations.

  14. Comparison of heat induced damage at the saphenofemoral junction after ablation with 1,470 nm laser or radiofrequency.

    PubMed

    Ozcinar, Evren; Cakici, Mehmet; Korun, Oktay; Han, Unsal; Kiziltepe, Ugursay

    2017-03-01

    The aim of this study was to evaluate the heat induced damage at the saphenofemoral junction level according to histopathological changes after radiofrequency or 1,470 nm radial tip laser ablation. Varicose vein segments of 6-10 mm in diameter were exposed to radiofrequency (Closure Fast catheter, 7 cm heat segment, one cycle, 15 seconds, 10 Watt, 120 °C) or laser ablation (1,470 nm radial tip, continuous wave, vein diameter: 6 cm/8 cm/10 cm-power: 10 Watt-pullback speed: 2.2 mm/s, 1.7 mm/s, 1.3 mm/s-LEED: 45J/cm, 60J/cm, 75J/cm-EFE 25J/cm 2 , respectively). Approximate 2 cm segments of the vein were left untreated, then histopathological examinations of the untouched segments (5 slices: level 1 - furthest segment, level 2 - nearest segment) for heat induced damage were performed. A total damage scoring system was established, including the presence of endothelial swelling, intimal thickening, cellular vacuolisation in the muscle layer, oedema in the tunica media, and extent of necrosis. At level 1, the furthest segment of the specimen, there was no significant difference between the laser and control group, while the total damage score of the radiofrequency group was significantly higher than the control group (p < 0.01). Radiofrequency group had higher total damage score compared to the laser group at level 1 (p < 0.01), 2 (p < 0.01), and 5 (p < 0.01); while no significant difference was observed at level 3 (p = 0.46) and 4 (p = 0.13). Significant heat induced damage may be seen even if the 2 cm segment of the vessel is left unablated. Radiofrequency ablation seems to cause more histological damage than laser ablation in this ex vivo study. Further in vivo studies are necessary, in order to validate these findings.

  15. Accelerated damage visualization using binary search with fixed pitch-catch distance laser ultrasonic scanning

    NASA Astrophysics Data System (ADS)

    Park, Byeongjin; Sohn, Hoon

    2017-07-01

    Laser ultrasonic scanning, especially full-field wave propagation imaging, is attractive for damage visualization thanks to its noncontact nature, sensitivity to local damage, and high spatial resolution. However, its practicality is limited because scanning at a high spatial resolution demands a prohibitively long scanning time. Inspired by binary search, an accelerated damage visualization technique is developed to visualize damage with a reduced scanning time. The pitch-catch distance between the excitation point and the sensing point is also fixed during scanning to maintain a high signal-to-noise ratio (SNR) of measured ultrasonic responses. The approximate damage boundary is identified by examining the interactions between ultrasonic waves and damage observed at the scanning points that are sparsely selected by a binary search algorithm. Here, a time-domain laser ultrasonic response is transformed into a spatial ultrasonic domain response using a basis pursuit approach so that the interactions between ultrasonic waves and damage, such as reflections and transmissions, can be better identified in the spatial ultrasonic domain. Then, the area inside the identified damage boundary is visualized as damage. The performance of the proposed damage visualization technique is validated excusing a numerical simulation performed on an aluminum plate with a notch and experiments performed on an aluminum plate with a crack and a wind turbine blade with delamination. The proposed damage visualization technique accelerates the damage visualization process in three aspects: (1) the number of measurements that is necessary for damage visualization is dramatically reduced by a binary search algorithm; (2) the number of averaging that is necessary to achieve a high SNR is reduced by maintaining the wave propagation distance short; and (3) with the proposed technique, the same damage can be identified with a lower spatial resolution than the spatial resolution required by full

  16. Development of high damage threshold multilayer thin film beam combiner for laser application

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nand, Mangla, E-mail: mnand@rrcat.gov.in; Babita,; Jena, S.

    2016-05-23

    A polarized wavelength multiplexer with high laser induced damage threshold has been developed to combine two laser beam of high peak power in the visible region. The present wavelength multiplexer is a multilayer thin film device deposited by reactive electron beam evaporation. The developed device is capable of combining two p-polarized laser beams of peak power density of 1.7 GW/cm{sup 2} at an angle of incidence of 45°. High transmission (T> 90%) in high pass region and high reflection (R> 99%) in stop band region have been achieved.

  17. Development of high damage threshold multilayer thin film beam combiner for laser application

    NASA Astrophysics Data System (ADS)

    Nand, Mangla; Babita, Jena, S.; Tokas, R. B.; Rajput, P.; Mukharjee, C.; Thakur, S.; Jha, S. N.; Sahoo, N. K.

    2016-05-01

    A polarized wavelength multiplexer with high laser induced damage threshold has been developed to combine two laser beam of high peak power in the visible region. The present wavelength multiplexer is a multilayer thin film device deposited by reactive electron beam evaporation. The developed device is capable of combining two p-polarized laser beams of peak power density of 1.7 GW/cm2 at an angle of incidence of 45°. High transmission (T> 90%) in high pass region and high reflection (R> 99%) in stop band region have been achieved.

  18. Extensive tissue damage of bovine ovaries after bipolar ovarian drilling compared to monopolar electrocoagulation or carbon dioxide laser.

    PubMed

    Hendriks, Marja-Liisa; van der Valk, Paul; Lambalk, Cornelis B; Broeckaert, Mark A M; Homburg, Roy; Hompes, Peter G A

    2010-02-01

    To evaluate the size of ovarian damage caused by ovarian drilling in polycystic ovary syndrome, the amount of inflicted damage was assessed for the most frequently used ovarian drilling techniques. Experimental prospective design. University clinic. Six fresh bovine ovaries per technique. Carbon dioxide (CO(2)) laser, monopolar electrocoagulation, and bipolar electrocoagulation were used for in vitro ovarian drilling. Amount of inflicted ovarian damage per procedure. Bipolar electrocoagulation resulted in significantly more destruction per burn than the CO(2) laser and monopolar electrocoagulation (287.6 versus 24.0 and 70.0 mm(3), respectively). The damage found per lesion was multiplied by the regularly applied number of punctures per procedure in daily practice (based on the literature). Again, the bipolar electrocoagulation resulted in significantly more tissue damage than the CO(2) laser and monopolar coagulation (2,876 versus 599 and 700 mm(3), respectively). Ovarian drilling, especially bipolar electrocoagulation, causes extensive destruction of the ovary. Given the same clinical effectiveness of the various procedures, it is essential to use the lowest possible dose that works; thus, the first choice should be CO(2) laser or monopolar electrocoagulation. Copyright 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  19. CW laser damage testing of RAR nano-textured fused silica and YAG

    NASA Astrophysics Data System (ADS)

    MacLeod, Bruce D.; Hobbs, Douglas S.; Manni, Anthony D.; Sabatino, Ernest; Bernot, David M.; DeFrances, Sage; Randi, Joseph A.; Thomas, Jeffrey

    2017-11-01

    A study of the continuous wave (CW) laser induced damage threshold (LiDT) of fused silica and yttrium aluminum garnet (YAG) optics was conducted to further illustrate the enhanced survivability within high power laser systems of an anti-reflection (AR) treatment consisting of randomly distributed surface relief nanostructures (RAR). A series of three CW LiDT tests using the 1070nm wavelength, 16 KW fiber laser test bed at Penn State Electro-Optic Center (PSEOC) were designed and completed, with improvements in the testing protocol, areal coverage, and maximum exposure intensities implemented between test cycles. Initial results for accumulated power, stationary site exposures of RAR nano-textured optics showed no damage and low surface temperatures similar to the control optics with no AR treatment. In contrast, optics with thin-film AR coatings showed high surface temperatures consistent with absorption by the film layers. Surface discriminating absorption measurements made using the Photothermal Common-path Interferometry (PCI) method, showed zero added surface absorption for the RAR nanotextured optics, and absorption levels in the 2-5 part per million range for thin-film AR coated optics. In addition, the surface absorption of thin-film AR coatings was also found to have localized absorption spikes that are likely pre-cursors for damage. Subsequent CW LiDT testing protocol included raster scanning an increased intensity focused beam over the test optic surface where it was found that thin-film AR coated optics damaged at intensities in the 2 to 5 MW/cm2 range with surface temperatures over 250C during the long-duration exposures. Significantly, none of the 10 RAR nano-textured fused silica optics tested could be damaged up to the maximum system intensity of 15.5 MW/cm2, and surface temperatures remained low. YAG optics tested during the final cycle exhibited a similar result with RAR nano-textured surfaces surviving intensities over 3 times higher than thin

  20. Investigation of Laser-Induced Retinal Damage: Wavelength and Pulsewidth Dependent Mechanisms

    DTIC Science & Technology

    1994-06-30

    Jun, Fos and the AP-1 complex in cell-proliferation and transformation. Biochim Biophys Acta 1991;1072:129-57. 2. Artuc M, Ramshad M, Kappus H. Studies...M, Reinhold C, Kappus H. DNA damage caused by laser light activated hematoporphyrin derivatives in isolated nuclei of human melanoma cells. Arch

  1. Optical control of filamentation-induced damage to DNA by intense, ultrashort, near-infrared laser pulses

    PubMed Central

    Dharmadhikari, J. A.; Dharmadhikari, A. K.; Kasuba, K. C.; Bharambe, H.; D’Souza, J. S.; Rathod, K. D.; Mathur, D.

    2016-01-01

    We report on damage to DNA in an aqueous medium induced by ultrashort pulses of intense laser light of 800 nm wavelength. Focusing of such pulses, using lenses of various focal lengths, induces plasma formation within the aqueous medium. Such plasma can have a spatial extent that is far in excess of the Rayleigh range. In the case of water, the resulting ionization and dissociation gives rise to in situ generation of low-energy electrons and OH-radicals. Interactions of these with plasmid DNA produce nicks in the DNA backbone: single strand breaks (SSBs) are induced as are, at higher laser intensities, double strand breaks (DSBs). Under physiological conditions, the latter are not readily amenable to repair. Systematic quantification of SSBs and DSBs at different values of incident laser energy and under different external focusing conditions reveals that damage occurs in two distinct regimes. Numerical aperture is the experimental handle that delineates the two regimes, permitting simple optical control over the extent of DNA damage. PMID:27279565

  2. Laser-induced retinal damage thresholds for annular retinal beam profiles

    NASA Astrophysics Data System (ADS)

    Kennedy, Paul K.; Zuclich, Joseph A.; Lund, David J.; Edsall, Peter R.; Till, Stephen; Stuck, Bruce E.; Hollins, Richard C.

    2004-07-01

    The dependence of retinal damage thresholds on laser spot size, for annular retinal beam profiles, was measured in vivo for 3 μs, 590 nm pulses from a flashlamp-pumped dye laser. Minimum Visible Lesion (MVL)ED50 thresholds in rhesus were measured for annular retinal beam profiles covering 5, 10, and 20 mrad of visual field; which correspond to outer beam diameters of roughly 70, 160, and 300 μm, respectively, on the primate retina. Annular beam profiles at the retinal plane were achieved using a telescopic imaging system, with the focal properties of the eye represented as an equivalent thin lens, and all annular beam profiles had a 37% central obscuration. As a check on experimental data, theoretical MVL-ED50 thresholds for annular beam exposures were calculated using the Thompson-Gerstman granular model of laser-induced thermal damage to the retina. Threshold calculations were performed for the three experimental beam diameters and for an intermediate case with an outer beam diameter of 230 μm. Results indicate that the threshold vs. spot size trends, for annular beams, are similar to the trends for top hat beams determined in a previous study; i.e., the threshold dose varies with the retinal image area for larger image sizes. The model correctly predicts the threshold vs. spot size trends seen in the biological data, for both annular and top hat retinal beam profiles.

  3. A Visualization Method for Corrosion Damage on Aluminum Plates Using an Nd:YAG Pulsed Laser Scanning System.

    PubMed

    Lee, Inbok; Zhang, Aoqi; Lee, Changgil; Park, Seunghee

    2016-12-16

    This paper proposes a non-contact nondestructive evaluation (NDE) technique that uses laser-induced ultrasonic waves to visualize corrosion damage in aluminum alloy plate structures. The non-contact, pulsed-laser ultrasonic measurement system generates ultrasonic waves using a galvanometer-based Q-switched Nd:YAG laser and measures the ultrasonic waves using a piezoelectric (PZT) sensor. During scanning, a wavefield can be acquired by changing the excitation location of the laser point and measuring waves using the PZT sensor. The corrosion damage can be detected in the wavefield snapshots using the scattering characteristics of the waves that encounter corrosion. The structural damage is visualized by calculating the logarithmic values of the root mean square (RMS), with a weighting parameter to compensate for the attenuation caused by geometrical spreading and dispersion of the waves. An intact specimen is used to conduct a comparison with corrosion at different depths and sizes in other specimens. Both sides of the plate are scanned with the same scanning area to observe the effect of the location where corrosion has formed. The results show that the damage can be successfully visualized for almost all cases using the RMS-based functions, whether it formed on the front or back side. Also, the system is confirmed to have distinguished corroded areas at different depths.

  4. Laser abrasion for cosmetic and medical treatment of facial actinic damage

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    David, L.M.; Lask, G.P.; Glassberg, E.

    1989-06-01

    Previous studies have shown the carbon dioxide (CO/sub 2/) laser to be effective in the treatment of actinic cheilitis. After CO/sub 2/ laser abrasion, normal skin and marked cosmetic improvement of the lip were noted. In our study, twenty-three patients were treated with CO/sub 2/ laser abrasions for cosmetic improvement of facial lines and actinic changes. Pre- and postoperative histopathologic examinations were made on two patients. Preoperative examination of specimens from actinically damaged skin showed atypical keratinocytes in the basal layer of the epidermis, with overlying dense compact orthokeratosis and parakeratosis. Abundant solar elastosis was seen in the papillary dermis.more » Postoperative histologic specimens showed a normal-appearing epidermis with fibrosis in the papillary dermis and minimal solar elastosis (about four weeks after laser treatment). At present, various modalities are available for the regeneration of the aged skin, including chemical peels and dermabrasion. Significantly fewer complications were noted with CO/sub 2/ laser abrasion than with these methods. Thus, CO/sub 2/ laser abrasion can be useful in the cosmetic and medical treatment of the aged skin. Marked clinical and histologic improvement has been demonstrated.« less

  5. Report on the Study of Radiation Damage in Calcium Fluoride and Magnesium Fluoride Crystals for use in Excimer Laser Applications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None, None

    1999-10-04

    A study was performed to investigate the effects of radiation damage in calcium fluoride and magnesium fluoride crystals caused by gamma rays and UV photons from excimer lasers. The purpose was to study and correlate the damage caused by these two different mechanisms in various types of material used for fabricating optical elements in high power excimer lasers and lens systems of lithography tools. These optical systems are easily damaged by the laser itself, and it is necessary to use only the most radiation resistant materials for certain key elements. It was found that a clear correlation exists between the,more » radiation induced damage caused by high energy gamma rays and that produced by UV photons from the excimer laser. This correlation allows a simple procedure to be developed to select the most radiation resistant material at the ingot level, which would be later used to fabricate various components of the optical system. This avoids incurring the additional cost of fabricating actual optical elements with material that would later be damaged under prolonged use. The result of this screening procedure can result in a considerable savings in the overall cost of the lens and laser system.« less

  6. Multifocal electroretinogram (MFERG) evaluation of laser-induced secondary damage in the non-human primate (NHP)

    NASA Astrophysics Data System (ADS)

    Zwick, Harry; Stuck, Bruce E.; Akers, A.; Edsall, Peter; DiCarlo, Cheryl D.; Lund, David J.

    2005-04-01

    Laser induced retinal damage may involve primary injury to the central retina and secondary damage, including intraretinal scar formation (IRSF) retinal traction (RT) and retinal nerve fiber layer injury (RNFL). We have evaluated these laser induced retinal pathologies with MFERG in non-human primates (NHPs) with a Veris (4.9) MFERG system 103 Hexagons, centered on the macula with non-scaled arrays and in one NHP with a 2-frame/M-step sequence to assess long term exposure effects within the RNFL. Chemical restraint was achieved using Ketamine stability HCL (10 mg/kg IM) and Propofol (0.5 mg-1.2/Kg/min via syringe pump). Peribulbar eye blocks were performed using 2% lidocain or a mixture of 2% Lidocain/Marcain (monitored ocular motility was less than 40 microns in retinal space). Primary and secondary damage effects were induced with either q-switched single pulse Neodymium (1064 nm, 1.0 mJ) or Argon CW (10 to 1000 msec, 10-150 mW). MFERG demonstrated capability to detect primary and secondary induced retinal damage in both 1st and 2nd order kernels. Primary and secondary damage in the central retina was often suppressed in amplitude and with longer latencies relative to the MFERG norm. Preliminary investigations in one NHP with Primary and secondary RNFL damage at 9 to 14 months showed recovery with non-scaled array one frame / M-step sequence but demonstrated significant abnormalities for a two frame/ M-step sequence. Utilization of advanced Veris recording parameters involving spatial and temporal manipulation of the stimulus parameters can improve detection of functional deficits induced by focal laser retinal injury.

  7. Use of near infrared femtosecond lasers as sub-micron radiation microbeam for cell DNA damage and repair studies.

    PubMed

    Botchway, S W; Reynolds, P; Parker, A W; O'Neill, P

    2010-01-01

    Laser induced radiation microbeam technology for radiobiology research is undergoing rapid growth because of the increased availability and ease of use of femtosecond laser sources. The main processes involved are multiphoton absorption and/or plasma formation. The high peak powers these lasers generate make them ideal tools for depositing sub-micrometer size radiant energy within a region of a living cell nucleus to activate ionising and/or photochemically driven processes. The technique allows questions relating to the effects of low doses of radiation, the propagation and treatment of deoxyribonucleic acid (DNA) damage and repair in individual live cells as well as non-targeted cell to cell effects to be addressed. This mini-review focuses on the use of near infrared (NIR) ca. 800nm radiation to induce damage that is radically different from the early and subsequent ultraviolet microbeam techniques. Ultrafast pulsed NIR instrumentation has many benefits including the ability to eliminate issues of unspecific UV absorption by the many materials prevalent within cells. The multiphoton interaction volume also permits energy deposition beyond the diffraction limit. Work has established that the fundamental process of the damage induced by the ultrashort laser pulses is different to those induced from continuous wave light sources. Pioneering work has demonstrated that NIR laser microbeam radiation can mimic ionising radiation via multiphoton absorption within the 3D femtolitre volume of the highly focused Gaussian beam. This light-matter interaction phenomenon provides a novel optical microbeam probe for mimicking both complex ionising and UV radiation-type cell damage including double strand breaks (DSBs) and base damage. A further advantage of the pulsed laser technique is that it provides further scope for time-resolved experiments. Recently the NIR laser microbeam technique has been used to investigate the recruitment of repair proteins to the sub

  8. Quantifying Post- Laser Ablation Prostate Therapy Changes on MRI via a Domain-Specific Biomechanical Model: Preliminary Findings

    PubMed Central

    Toth, Robert; Sperling, Dan; Madabhushi, Anant

    2016-01-01

    Focal laser ablation destroys cancerous cells via thermal destruction of tissue by a laser. Heat is absorbed, causing thermal necrosis of the target region. It combines the aggressive benefits of radiation treatment (destroying cancer cells) without the harmful side effects (due to its precise localization). MRI is typically used pre-treatment to determine the targeted area, and post-treatment to determine efficacy by detecting necrotic tissue, or tumor recurrence. However, no system exists to quantitatively evaluate the post-treatment effects on the morphology and structure via MRI. To quantify these changes, the pre- and post-treatment MR images must first be spatially aligned. The goal is to quantify (a) laser-induced shape-based changes, and (b) changes in MRI parameters post-treatment. The shape-based changes may be correlated with treatment efficacy, and the quantitative effects of laser treatment over time is currently poorly understood. This work attempts to model changes in gland morphology following laser treatment due to (1) patient alignment, (2) changes due to surrounding organs such as the bladder and rectum, and (3) changes due to the treatment itself. To isolate the treatment-induced shape-based changes, the changes from (1) and (2) are first modeled and removed using a finite element model (FEM). A FEM models the physical properties of tissue. The use of a physical biomechanical model is important since a stated goal of this work is to determine the physical shape-based changes to the prostate from the treatment, and therefore only physical real deformations are to be allowed. A second FEM is then used to isolate the physical, shape-based, treatment-induced changes. We applied and evaluated our model in capturing the laser induced changes to the prostate morphology on eight patients with 3.0 Tesla, T2-weighted MRI, acquired approximately six months following treatment. Our results suggest the laser treatment causes a decrease in prostate volume

  9. Spectral and temperature-dependent infrared emissivity measurements of painted metals for improved temperature estimation during laser damage testing

    NASA Astrophysics Data System (ADS)

    Baumann, Sean M.; Keenan, Cameron; Marciniak, Michael A.; Perram, Glen P.

    2014-10-01

    A database of spectral and temperature-dependent emissivities was created for painted Al-alloy laser-damage-testing targets for the purpose of improving the uncertainty to which temperature on the front and back target surfaces may be estimated during laser-damage testing. Previous temperature estimates had been made by fitting an assumed gray-body radiance curve to the calibrated spectral radiance data collected from the back surface using a Telops Imaging Fourier Transform Spectrometer (IFTS). In this work, temperature-dependent spectral emissivity measurements of the samples were made from room temperature to 500 °C using a Surface Optics Corp. SOC-100 Hemispherical Directional Reflectometer (HDR) with Nicolet FTS. Of particular interest was a high-temperature matte-black enamel paint used to coat the rear surfaces of the Al-alloy samples. The paint had been assumed to have a spectrally flat and temperatureinvariant emissivity. However, the data collected using the HDR showed both spectral variation and temperature dependence. The uncertainty in back-surface temperature estimation during laser-damage testing made using the measured emissivities was improved from greater than +10 °C to less than +5 °C for IFTS pixels away from the laser burn-through hole, where temperatures never exceeded those used in the SOC-100 HDR measurements. At beam center, where temperatures exceeded those used in the SOC-100 HDR, uncertainty in temperature estimates grew beyond those made assuming gray-body emissivity. Accurate temperature estimations during laser-damage testing are useful in informing a predictive model for future high-energy-laser weapon applications.

  10. Identification of the formation phases of filamentary damage induced by nanosecond laser pulses in bulk fused silica

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shen, Chao; Xu, Zhongjie; Chambonneau, Maxime, E-mail: chambonneau@lp3.univ-mrs.fr, E-mail: jiangtian198611@163.com

    2015-09-14

    Employing a pump-probe polarization-based two-frame shadowgraphy setup, the formation of filamentary damage induced in bulk fused silica by a nanosecond pulse at 1064 nm is investigated with a picosecond probe. Three different phases are exhibited in the damage experiments. The first phase is the formation of a micrometric plasma channel along the laser direction during the beginning of the pulse likely caused by multi-photon ionization. This channel exhibits growth during ∼400 ps, and the newly grown plasma is discrete. Then, during the end of the pulse, this channel evolves into a tadpole-like morphology showing an elliptical head upstream the laser fluxmore » followed by a thin tail. This observed asymmetry is attributed to shielding effects caused by both the plasma and hot modified silica. Once the damage shows its almost final morphology, a last phase consists in the launch of a pressure wave enlarging it after the laser pulse. The physical mechanisms that might be involved in the formation of plasma channels are discussed. The experimental data are first confronted to the moving breakdown model which overestimates the filamentary damage length. Finally, taking into account the temporal shape of the laser pulses, the coupling between Kerr-induced self-focusing and stimulated Brillouin scattering is discussed to interpret the observations.« less

  11. A Visualization Method for Corrosion Damage on Aluminum Plates Using an Nd:YAG Pulsed Laser Scanning System

    PubMed Central

    Lee, Inbok; Zhang, Aoqi; Lee, Changgil; Park, Seunghee

    2016-01-01

    This paper proposes a non-contact nondestructive evaluation (NDE) technique that uses laser-induced ultrasonic waves to visualize corrosion damage in aluminum alloy plate structures. The non-contact, pulsed-laser ultrasonic measurement system generates ultrasonic waves using a galvanometer-based Q-switched Nd:YAG laser and measures the ultrasonic waves using a piezoelectric (PZT) sensor. During scanning, a wavefield can be acquired by changing the excitation location of the laser point and measuring waves using the PZT sensor. The corrosion damage can be detected in the wavefield snapshots using the scattering characteristics of the waves that encounter corrosion. The structural damage is visualized by calculating the logarithmic values of the root mean square (RMS), with a weighting parameter to compensate for the attenuation caused by geometrical spreading and dispersion of the waves. An intact specimen is used to conduct a comparison with corrosion at different depths and sizes in other specimens. Both sides of the plate are scanned with the same scanning area to observe the effect of the location where corrosion has formed. The results show that the damage can be successfully visualized for almost all cases using the RMS-based functions, whether it formed on the front or back side. Also, the system is confirmed to have distinguished corroded areas at different depths. PMID:27999252

  12. Thermal damage produced by high-irradiance continuous wave CO2 laser cutting of tissue.

    PubMed

    Schomacker, K T; Walsh, J T; Flotte, T J; Deutsch, T F

    1990-01-01

    Thermal damage produced by continuous wave (cw) CO2 laser ablation of tissue in vitro was measured for irradiances ranging from 360 W/cm2 to 740 kW/cm2 in order to investigate the extent to which ablative cooling can limit tissue damage. Damage zones thinner than 100 microns were readily produced using single pulses to cut guinea pig skin as well as bovine cornea, aorta, and myocardium. Multiple pulses can lead to increased damage. However, a systematic decrease in damage with irradiance, predicted theoretically by an evaporation model of ablation, was not observed. The damage-zone thickness was approximately constant around the periphery of the cut, consistent with the existence of a liquid layer which stores heat and leads to tissue damage, and with a model of damage and ablation recently proposed by Zweig et al.

  13. Thermal damage control of dye-assisted laser tissue welding: effect of dye concentration

    NASA Astrophysics Data System (ADS)

    Xie, Hua; Buckley, Lisa A.; Prahl, Scott A.; Shaffer, Brian S.; Gregory, Kenton W.

    2001-05-01

    Successful laser-assisted tissue welding was implemented to provide proper weld strength with minimized tissue thermal injury. We investigated and compared the weld strengths and morphologic changes in porcine small intestinal submucose (SIS) and porcine ureteral tissues with various concentration of indocyanine green (ICG) and with a solid albumin sheet. The study showed that the tissues were welded at lower ICG concentration (0.05 mM) with minimized tissue thermal damage using an 800-nm wavelength diode laser.

  14. Lifetime laser damage performance of β -Ga2O3 for high power applications

    NASA Astrophysics Data System (ADS)

    Yoo, Jae-Hyuck; Rafique, Subrina; Lange, Andrew; Zhao, Hongping; Elhadj, Selim

    2018-03-01

    Gallium oxide (Ga2O3) is an emerging wide bandgap semiconductor with potential applications in power electronics and high power optical systems where gallium nitride and silicon carbide have already demonstrated unique advantages compared to gallium arsenide and silicon-based devices. Establishing the stability and breakdown conditions of these next-generation materials is critical to assessing their potential performance in devices subjected to large electric fields. Here, using systematic laser damage performance tests, we establish that β-Ga2O3 has the highest lifetime optical damage performance of any conductive material measured to date, above 10 J/cm2 (1.4 GW/cm2). This has direct implications for its use as an active component in high power laser systems and may give insight into its utility for high-power switching applications. Both heteroepitaxial and bulk β-Ga2O3 samples were benchmarked against a heteroepitaxial gallium nitride sample, revealing an order of magnitude higher optical lifetime damage threshold for β-Ga2O3. Photoluminescence and Raman spectroscopy results suggest that the exceptional damage performance of β-Ga2O3 is due to lower absorptive defect concentrations and reduced epitaxial stress.

  15. Evaluating the Thermal Damage Resistance of Reduced Graphene Oxide/Carbon Nanotube Hybrid Coatings

    NASA Astrophysics Data System (ADS)

    David, Lamuel; Feldman, Ari; Mansfield, Elisabeth; Lehman, John; Singh, Gurpreet; National Institute of Standards and Technology Collaboration

    2014-03-01

    Carbon nanotubes and graphene are known to exhibit some exceptional thermal (K ~ 2000 to 4400 W.m-1K-1 at 300K) and optical properties. Here, we demonstrate preparation and testing of multiwalled carbon nanotubes and chemically modified graphene-composite spray coatings for use on thermal detectors for high-power lasers. The synthesized nanocomposite material was tested by preparing spray coatings on aluminum test coupons used as a representation of the thermal detector's surface. These coatings were then exposed to increasing laser powers and extended exposure times to quantify their damage threshold and optical absorbance. The graphene/carbon nanotube (prepared at varying mass% of graphene in CNTs) coatings demonstrated significantly higher damage threshold values at 2.5 kW laser power (10.6 μm wavelength) than carbon paint or MWCNTs alone. Electron microscopy and Raman spectroscopy of irradiated specimens showed that the composite coating endured high laser-power densities (up to 2 kW.cm-2) without significant visual damage. This research is based on work supported by the National Science Foundation (Chemical, Bioengineering, Environmental, and Transport Systems Division), under grant no. 1335862 to G. Singh.

  16. Long-range pulselength scaling of 351nm laser damage thresholds

    NASA Astrophysics Data System (ADS)

    Foltyn, S. R.; Jolin, L. J.

    1986-12-01

    In a series of experiments incorporating 351nm pulselength of 9, 26, 54, and 625ns, it was found that laser damage thresholds increased as (pulselength)/sup x/, and that the exponent averaged 0.36 and ranged, for different samples, from 0.23 to 0.48. Similar results were obtained when only catastrophic damage was considered. Samples included Al2O3/SiO2 in both AR and HR multilayers, HR's of Sc2O3/SiO2 and HfO2/SiO2, and Al-on-pyrex mirror; 9ns thresholds were between 0.2 to 5.6 J/sq cm. When these data were compared with a wide range of other results - for wavelengths from 0.25 to 10.6 microns and pulselengths down to 4ps - a remarkably consistent picture emerged. Damage thresholds, on average, increase approximately as the cube-root of pulselength from picoseconds to nearly a microsecond, and do so regardless of wavelength or material under test.

  17. Impact of storage induced outgassing organic contamination on laser induced damage of silica optics at 351 nm.

    PubMed

    Bien-Aimé, K; Belin, C; Gallais, L; Grua, P; Fargin, E; Néauport, J; Tovena-Pecault, I

    2009-10-12

    The impact of storage conditions on laser induced damage density at 351 nm on bare fused polished silica samples has been studied. Intentionally outgassing of polypropylene pieces on silica samples was done. We evidenced an important increase of laser induced damage density on contaminated samples demonstrating that storage could limit optics lifetime performances. Atomic Force Microscopy (AFM) and Gas Chromatography -Mass Spectrometry (GC-MS) have been used to identify the potential causes of this effect. It shows that a small quantity of organic contamination deposited on silica surface is responsible for this degradation. Various hypotheses are proposed to explain the damage mechanism. The more likely hypothesis is a coupling between surface defects of optics and organic contaminants.

  18. Damage threshold of coating materials on x-ray mirror for x-ray free electron laser

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Koyama, Takahisa, E-mail: koyama@spring8.or.jp; Yumoto, Hirokatsu; Tono, Kensuke

    2016-05-15

    We evaluated the damage threshold of coating materials such as Mo, Ru, Rh, W, and Pt on Si substrates, and that of uncoated Si substrate, for mirror optics of X-ray free electron lasers (XFELs). Focused 1 μm (full width at half maximum) XFEL pulses with the energies of 5.5 and 10 keV, generated by the SPring-8 angstrom compact free electron laser (SACLA), were irradiated under the grazing incidence condition. The damage thresholds were evaluated by in situ measurements of X-ray reflectivity degradation during irradiation by multiple pulses. The measured damage fluences below the critical angles were sufficiently high compared withmore » the unfocused SACLA beam fluence. Rh coating was adopted for two mirror systems of SACLA. One system was a beamline transport mirror system that was partially coated with Rh for optional utilization of a pink beam in the photon energy range of more than 20 keV. The other was an improved version of the 1 μm focusing mirror system, and no damage was observed after one year of operation.« less

  19. FEM modeling and histological analyses on thermal damage induced in facial skin resurfacing procedure with different CO2 laser pulse duration

    NASA Astrophysics Data System (ADS)

    Rossi, Francesca; Zingoni, Tiziano; Di Cicco, Emiliano; Manetti, Leonardo; Pini, Roberto; Fortuna, Damiano

    2011-07-01

    Laser light is nowadays routinely used in the aesthetic treatments of facial skin, such as in laser rejuvenation, scar removal etc. The induced thermal damage may be varied by setting different laser parameters, in order to obtain a particular aesthetic result. In this work, it is proposed a theoretical study on the induced thermal damage in the deep tissue, by considering different laser pulse duration. The study is based on the Finite Element Method (FEM): a bidimensional model of the facial skin is depicted in axial symmetry, considering the different skin structures and their different optical and thermal parameters; the conversion of laser light into thermal energy is modeled by the bio-heat equation. The light source is a CO2 laser, with different pulse durations. The model enabled to study the thermal damage induced into the skin, by calculating the Arrhenius integral. The post-processing results enabled to study in space and time the temperature dynamics induced in the facial skin, to study the eventual cumulative effects of subsequent laser pulses and to optimize the procedure for applications in dermatological surgery. The calculated data where then validated in an experimental measurement session, performed in a sheep animal model. Histological analyses were performed on the treated tissues, evidencing the spatial distribution and the entity of the thermal damage in the collageneous tissue. Modeling and experimental results were in good agreement, and they were used to design a new optimized laser based skin resurfacing procedure.

  20. Wavelength dependence of nanosecond laser induced surface damage in fused silica from 260 to 1550 nm

    NASA Astrophysics Data System (ADS)

    Cao, Ming; Cao, Jianjun; Liu, Mian; Sun, Yuan; Wu, Meng; Guo, Shiming; Gao, Shumei

    2018-04-01

    The wavelength dependence of laser induced surface damage in fused silica is experimentally studied in a wide wavelength range from 260 to 1550 nm. An optical parametric oscillator system is used to provide the tunable laser pulses with a duration of 5 ns. In the experiments, the exit surface of the silica slice is observed to be damaged prior to the entrance surface. The damage threshold decreases gradually as the wavelength decreases from 1550 to 324 nm and drops suddenly at 324 nm, which corresponds to a half of 7.66 eV. This wavelength dependence can be explained by a defect assisted multiphoton absorption mechanism. By fitting the experimental data with a power law equation, the damage threshold is found to be proportional to the 3.47-th power of wavelength in the range of 325-685 nm and 1.1-th power of wavelength in the range of 260-1550 nm.

  1. Method for quantifying percentage wood failure in block-shear specimens by a laser scanning profilometer

    Treesearch

    C. T. Scott; R. Hernandez; C. Frihart; R. Gleisner; T. Tice

    2005-01-01

    A new method for quantifying percentage wood failure of an adhesively bonded block-shear specimen has been developed. This method incorporates a laser displacement gage with an automated two-axis positioning system that functions as a highly sensitive profilometer. The failed specimen is continuously scanned across its width to obtain a surface failure profile. The...

  2. Quantifying Traces of Tool Use: A Novel Morphometric Analysis of Damage Patterns on Percussive Tools

    PubMed Central

    Caruana, Matthew V.; Carvalho, Susana; Braun, David R.; Presnyakova, Darya; Haslam, Michael; Archer, Will; Bobe, Rene; Harris, John W. K.

    2014-01-01

    Percussive technology continues to play an increasingly important role in understanding the evolution of tool use. Comparing the archaeological record with extractive foraging behaviors in nonhuman primates has focused on percussive implements as a key to investigating the origins of lithic technology. Despite this, archaeological approaches towards percussive tools have been obscured by a lack of standardized methodologies. Central to this issue have been the use of qualitative, non-diagnostic techniques to identify percussive tools from archaeological contexts. Here we describe a new morphometric method for distinguishing anthropogenically-generated damage patterns on percussive tools from naturally damaged river cobbles. We employ a geomatic approach through the use of three-dimensional scanning and geographical information systems software to statistically quantify the identification process in percussive technology research. This will strengthen current technological analyses of percussive tools in archaeological frameworks and open new avenues for translating behavioral inferences of early hominins from percussive damage patterns. PMID:25415303

  3. Calculation of femtosecond pulse laser induced damage threshold for broadband antireflective microstructure arrays.

    PubMed

    Jing, Xufeng; Shao, Jianda; Zhang, Junchao; Jin, Yunxia; He, Hongbo; Fan, Zhengxiu

    2009-12-21

    In order to more exactly predict femtosecond pulse laser induced damage threshold, an accurate theoretical model taking into account photoionization, avalanche ionization and decay of electrons is proposed by comparing respectively several combined ionization models with the published experimental measurements. In addition, the transmittance property and the near-field distribution of the 'moth eye' broadband antireflective microstructure directly patterned into the substrate material as a function of the surface structure period and groove depth are performed by a rigorous Fourier model method. It is found that the near-field distribution is strongly dependent on the periodicity of surface structure for TE polarization, but for TM wave it is insensitive to the period. What's more, the femtosecond pulse laser damage threshold of the surface microstructure on the pulse duration taking into account the local maximum electric field enhancement was calculated using the proposed relatively accurate theoretical ionization model. For the longer incident wavelength of 1064 nm, the weak linear damage threshold on the pulse duration is shown, but there is a surprising oscillation peak of breakdown threshold as a function of the pulse duration for the shorter incident wavelength of 532 nm.

  4. Tm:fiber laser ablation with real-time temperature monitoring for minimizing collateral thermal damage: ex vivo dosimetry for ovine brain.

    PubMed

    Tunc, Burcu; Gulsoy, Murat

    2013-01-01

    The thermal damage of the surrounding tissue can be an unwanted result of continuous-wave laser irradiations. In order to propose an effective alternative to conventional surgical techniques, photothermal damage must be taken under control by a detailed dose study. Real-time temperature monitoring can be also an effective way to get rid of these negative effects. The aim of the present study is to investigate the potential of a new laser-thermoprobe, which consists of a continuous-wave 1,940-nm Tm:fiber laser and a thermocouple measurement system for brain surgery in an ex vivo study. A laser-thermoprobe was designed for using the near-by tissue temperature as a real-time reference for the applicator. Fresh lamb brain tissues were used for experiments. 320 laser shots were performed on both cortical and subcortical tissue. The relationship between laser parameters, temperature changes, and ablation (removal of tissue) efficiency was determined. The correlation between rate of temperature change and ablation efficiency was calculated. Laser-thermoprobe leads us to understand the basic laser-tissue interaction mechanism in a very cheap and easy way, without making a change in the experimental design. It was also shown that the ablation and coagulation (thermally irreversible damage) diameters could be predicted, and carbonization can be avoided by temperature monitoring. Copyright © 2013 Wiley Periodicals, Inc.

  5. Porcine skin damage thresholds for pulsed nanosecond-scale laser exposure at 1064-nm

    NASA Astrophysics Data System (ADS)

    DeLisi, Michael P.; Peterson, Amanda M.; Noojin, Gary D.; Shingledecker, Aurora D.; Tijerina, Amanda J.; Boretsky, Adam R.; Schmidt, Morgan S.; Kumru, Semih S.; Thomas, Robert J.

    2018-02-01

    Pulsed high-energy lasers operating in the near-infrared (NIR) band are increasingly being used in medical, industrial, and military applications, but there are little available experimental data to characterize their hazardous effects on skin tissue. The current American National Standard for the Safe Use of Lasers (ANSI Z136.1-2014) defines the maximum permissible exposure (MPE) on the skin as either a single-pulse or total exposure time limit. This study determined the minimum visible lesion (MVL) damage thresholds in Yucatan miniature pig skin for the single-pulse case and several multiple-pulse cases over a wide range of pulse repetition frequencies (PRFs) (10, 125, 2,000, and 10,000 Hz) utilizing nanosecond-scale pulses (10 or 60 ns). The thresholds are expressed in terms of the median effective dose (ED50) based on varying individual pulse energy with other laser parameters held constant. The results confirm a decrease in MVL threshold as PRF increases for exposures with a constant number of pulses, while also noting a PRF-dependent change in the threshold as a function of the number of pulses. Furthermore, this study highlights a change in damage mechanism to the skin from melanin-mediated photomechanical events at high irradiance levels and few numbers of pulses to bulk tissue photothermal additivity at lower irradiance levels and greater numbers of pulses. The observed trends exceeded the existing exposure limits by an average factor of 9.1 in the photothermally-damaged cases and 3.6 in the photomechanicallydamaged cases.

  6. Damage detection in sandwich composite materials using laser vibrometry in conjunction with nonlinear system identification

    NASA Astrophysics Data System (ADS)

    Underwood, Sara; Koester, David; Adams, Douglas E.

    2009-03-01

    Fiberglass sandwich panels are tested to study a vibration-based method for locating damage in composite materials. This method does not rely on a direct comparison of the natural frequencies, mode shapes, or residues in the forced vibration response data. Specifically, a nonlinear system identification based method for damage detection is sought that reduces the sensitivity of damage detection results to changes in vibration measurements due to variations in boundary conditions, environmental conditions, and material properties of the panel. Damage mechanisms considered include a disbond between the core and face sheet and a crack within the core. A panel is excited by a skewed piezoelectric actuator over a broad frequency range while a three-dimensional scanning laser vibrometer measures the surface velocity of the panel along three orthogonal axes. The forced frequency response data measured using the scanning laser vibrometer at multiple excitation amplitudes is processed to identify areas of the panel that exhibit significant nonlinear response characteristics. It is demonstrated that these localized nonlinearities in the panel coincide with the damaged areas of the composite material. Because changes in the measured frequency response functions due to nonlinear distortions associated with the damage can be identified without comparing the vibration data to a reference (baseline) signature of the undamaged material, this vibration technique for damage detection in composite materials exhibits less sensitivity to variations in the underlying linear characteristics than traditional methods. It is also demonstrated that the damage at a given location can be classified as either due to a disbond or core crack because these two types of damage produce difference signatures when comparing the multi-amplitude frequency response functions.

  7. Effects of γ-ray irradiation on optical absorption and laser damage performance of KDP crystals containing arsenic impurities.

    PubMed

    Guo, D C; Jiang, X D; Huang, J; Wang, F R; Liu, H J; Xiang, X; Yang, G X; Zheng, W G; Zu, X T

    2014-11-17

    The effects of γ-irradiation on potassium dihydrogen phosphate crystals containing arsenic impurities are investigated with different optical diagnostics, including UV-VIS absorption spectroscopy, photo-thermal common-path interferometer and photoluminescence spectroscopy. The optical absorption spectra indicate that a new broad absorption band near 260 nm appears after γ-irradiation. It is found that the intensity of absorption band increases with the increasing irradiation dose and arsenic impurity concentration. The simulation of radiation defects show that this absorption is assigned to the formation of AsO₄⁴⁻ centers due to arsenic ions substituting for phosphorus ions. Laser-induced damage threshold test is conducted by using 355 nm nanosecond laser pulses. The correlations between arsenic impurity concentration and laser induced damage threshold are presented. The results indicate that the damage performance of the material decreases with the increasing arsenic impurity concentration. Possible mechanisms of the irradiation-induced defects formation under γ-irradiation of KDP crystals are discussed.

  8. Laser pulse transmission and damage threshold of silica fibers with antireflective coatings

    NASA Astrophysics Data System (ADS)

    Meister, Stefan; Wosniok, Alexander; Riesbeck, Thomas; Scharfenorth, Chris; Eichler, Hans J.

    2005-03-01

    Standard 200 μm multimode fibers with Ta2O5/SiO2 antireflective coatings reach a transmission of more than 99.5% below the threshold of stimulated Brillouin scattering. The laser-induced damage threshold measured at 1064 nm and 24 ns pulse duration was about half than the LIDT of uncoated fibers.

  9. Dentinal temperature transients caused by exposure to CO2 laser irradiation and possible pulpal damage.

    PubMed

    Jeffrey, I W; Lawrenson, B; Saunders, E M; Longbottom, C

    1990-02-01

    An investigation is described that attempts to establish, in vitro, the characteristics of heat transference following laser irradiation of bovine dentinal tissue and the relationship with the periodicity of radiation. The results of this study appear to indicate that at depths of overlying dentine of up to 3 mm, laser-induced thermal injury to the pulp is a definite possibility. Fail-safe facilities to prevent build up of heat must be incorporated into the design of dental lasers to allow their beneficial effects to be utilized without the risk of iatrogenic damage.

  10. Real-time optical coherence tomography observation of retinal tissue damage during laser photocoagulation therapy on ex-vivo porcine samples

    NASA Astrophysics Data System (ADS)

    Steiner, P.; Považay, B.; Stoller, M.; Morgenthaler, P.; Inniger, D.; Arnold, P.; Sznitman, R.; Meier, Ch.

    2015-07-01

    Retinal laser photocoagulation represents a widely used treatment for retinal pathologies such as diabetic chorioretinopathy or diabetic edema. For effective treatment, an appropriate choice of the treatment energy dose is crucial to prevent excessive tissue damage caused by over-irradiation of the retina. In this manuscript we investigate simultaneous and time-resolved optical coherence tomography for its applicability to provide feedback to the ophthalmologist about the introduced retinal damage during laser photocoagulation. Time-resolved and volumetric optical coherence tomography data of 96 lesions on ex-vivo porcine samples, set with a 577 nm laser prototype and irradiance of between 300 and 8800 W=cm2 were analyzed. Time-resolved scans were compared to volumetric scans of the lesion and correlated with ophthalmoscopic visibility. Lastly, image parameters extracted from optical coherence tomography Mscans, suitable for lesion classification were identified. Results presented in this work support the hypothesis that simultaneous optical coherence tomography provides valuable information about the extent of retinal tissue damage and may be used to guide retinal laser photocoagulation in the future.

  11. Laser damage initiation and growth of antireflection coated S-FAP crystal surfaces prepared by pitch lap and magnetorheological finishing

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stolz, C J; Menapace, J A; Schaffers, K I

    Antireflection (AR) coatings typically damage at the interface between the substrate and coating. Therefore the substrate finishing technology can have an impact on the laser resistance of the coating. For this study, AR coatings were deposited on Yb:S-FAP [Yb{sup 3+}:Sr{sub 5}(PO{sub 4}){sub 3}F] crystals that received a final polish by both conventional pitch lap finishing as well as magnetorheological finishing (MRF). SEM images of the damage morphology reveals laser damage originates at scratches and at substrate coating interfacial absorbing defects. Previous damage stability tests on multilayer mirror coatings and bare surfaces revealed damage growth can occur at fluences below themore » initiation fluence. The results from this study suggest the opposite trend for AR coatings. Investigation of unstable HR and uncoated surface damage morphologies reveals significant radial cracking that is not apparent with AR damage due to AR delamination from the coated surface with few apparent cracks at the damage boundary. Damage stability tests show that coated Yb:S-FAP crystals can operate at 1057 nm at fluences around 20 J/cm{sup 2} at 10 ns; almost twice the initiation damage threshold.« less

  12. Quantifying Damage at Multiple Loading Rates to Kevlar KM2 Fibers Due to Weaving and Finishing

    DTIC Science & Technology

    2013-06-01

    ARL-TR-6465 June 2013 Approved for public release; distribution is unlimited. NOTICES...ARL-TR-6465 June 2013 Quantifying Damage at Multiple Loading Rates to Kevlar KM2 Fibers Due to Weaving and Finishing Brett D. Sanborn...OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 1. REPORT DATE (DD-MM-YYYY) June 2013 2. REPORT TYPE Final 3. DATES

  13. Laser-driven mechanical fracture in fused silica

    NASA Astrophysics Data System (ADS)

    Dahmani, Faiz

    1999-10-01

    Fused silica, widely used as optical-window material in high-fluence requirements on glass and KrF lasers, experiences optical damage. Under fatigue conditions, the damage is initiated by slow crack growth and culminates, if not arrested, with catastrophic crack growth and implosive failure when the stress intensity approaches the critical value. Since laser-induced cracks cannot be eliminated entirely, the behavior of cracked structures under service conditions must be quantified to be predicted. Systematic scientific rules must be devised to characterize laser-induced cracks and their effects, and to predict if and when it may become necessary to replace the damaged components. This thesis makes a contribution toward this end. Measurements of fatigue failure strength of laser-cracked fused silica in air at room temperature for different number of laser pulses and laser fluences are presented. The failure-strength variability is found to be due mainly to the spectrum of crack depths. Agreement with theory suggests the incorporation of a residual term into the failure-strength equation. Experiments on residual stresses induced in fused silica by the presence of a laser-induced crack are carried out using two different techniques. Theoretical modelings show that this residual stress field is of shear nature and mouth-opening. A correlation between the reduction in fracture strength of fused silica and the increase of the residual-stress field is established, providing laser systems designers and operators with guidance on the rate of crack growth as well as on the stress-related ramifications such as laser-driven cracks entail. Specifically, a hoop-stress in the immediate vicinity of a crack growing along the beam propagation direction is identified as strongly coupling to both the laser fluence and the crack growth. This coupling prompted the question of whether or not breaking the hoop stress symmetry by some external perturbation will accelerate or stymie crack

  14. Wireless ultrasonic wavefield imaging via laser for hidden damage detection inside a steel box girder bridge

    NASA Astrophysics Data System (ADS)

    An, Yun-Kyu; Song, Homin; Sohn, Hoon

    2014-09-01

    This paper presents a wireless ultrasonic wavefield imaging (WUWI) technique for detecting hidden damage inside a steel box girder bridge. The proposed technique allows (1) complete wireless excitation of piezoelectric transducers and noncontact sensing of the corresponding responses using laser beams, (2) autonomous damage visualization without comparing against baseline data previously accumulated from the pristine condition of a target structure and (3) robust damage diagnosis even for real structures with complex structural geometries. First, a new WUWI hardware system was developed by integrating optoelectronic-based signal transmitting and receiving devices and a scanning laser Doppler vibrometer. Next, a damage visualization algorithm, self-referencing f-k filter (SRF), was introduced to isolate and visualize only crack-induced ultrasonic modes from measured ultrasonic wavefield images. Finally, the performance of the proposed technique was validated through hidden crack visualization at a decommissioned Ramp-G Bridge in South Korea. The experimental results reveal that the proposed technique instantaneously detects and successfully visualizes hidden cracks even in the complex structure of a real bridge.

  15. Highlighting the DNA damage response with ultrashort laser pulses in the near infrared and kinetic modeling

    PubMed Central

    Ferrando-May, Elisa; Tomas, Martin; Blumhardt, Philipp; Stöckl, Martin; Fuchs, Matthias; Leitenstorfer, Alfred

    2013-01-01

    Our understanding of the mechanisms governing the response to DNA damage in higher eucaryotes crucially depends on our ability to dissect the temporal and spatial organization of the cellular machinery responsible for maintaining genomic integrity. To achieve this goal, we need experimental tools to inflict DNA lesions with high spatial precision at pre-defined locations, and to visualize the ensuing reactions with adequate temporal resolution. Near-infrared femtosecond laser pulses focused through high-aperture objective lenses of advanced scanning microscopes offer the advantage of inducing DNA damage in a 3D-confined volume of subnuclear dimensions. This high spatial resolution results from the highly non-linear nature of the excitation process. Here we review recent progress based on the increasing availability of widely tunable and user-friendly technology of ultrafast lasers in the near infrared. We present a critical evaluation of this approach for DNA microdamage as compared to the currently prevalent use of UV or VIS laser irradiation, the latter in combination with photosensitizers. Current and future applications in the field of DNA repair and DNA-damage dependent chromatin dynamics are outlined. Finally, we discuss the requirement for proper simulation and quantitative modeling. We focus in particular on approaches to measure the effect of DNA damage on the mobility of nuclear proteins and consider the pros and cons of frequently used analysis models for FRAP and photoactivation and their applicability to non-linear photoperturbation experiments. PMID:23882280

  16. Spatiotemporal dynamics of DNA repair proteins following laser microbeam induced DNA damage – When is a DSB not a DSB?☆

    PubMed Central

    Reynolds, Pamela; Botchway, Stanley W.; Parker, Anthony W.; O’Neill, Peter

    2013-01-01

    The formation of DNA lesions poses a constant threat to cellular stability. Repair of endogenously and exogenously produced lesions has therefore been extensively studied, although the spatiotemporal dynamics of the repair processes has yet to be fully understood. One of the most recent advances to study the kinetics of DNA repair has been the development of laser microbeams to induce and visualize recruitment and loss of repair proteins to base damage in live mammalian cells. However, a number of studies have produced contradictory results that are likely caused by the different laser systems used reflecting in part the wavelength dependence of the damage induced. Additionally, the repair kinetics of laser microbeam induced DNA lesions have generally lacked consideration of the structural and chemical complexity of the DNA damage sites, which are known to greatly influence their reparability. In this review, we highlight the key considerations when embarking on laser microbeam experiments and interpreting the real time data from laser microbeam irradiations. We compare the repair kinetics from live cell imaging with biochemical and direct quantitative cellular measurements for DNA repair. PMID:23688615

  17. Laser treatment of female stress urinary incontinence: optical, thermal, and tissue damage simulations

    NASA Astrophysics Data System (ADS)

    Hardy, Luke A.; Chang, Chun-Hung; Myers, Erinn M.; Kennelly, Michael J.; Fried, Nathaniel M.

    2016-02-01

    Treatment of female stress urinary incontinence (SUI) by laser thermal remodeling of subsurface tissues is studied. Light transport, heat transfer, and thermal damage simulations were performed for transvaginal and transurethral methods. Monte Carlo (MC) provided absorbed photon distributions in tissue layers (vaginal wall, endopelvic fascia, urethral wall). Optical properties (n,μa,μs,g) were assigned to each tissue at λ=1064 nm. A 5-mm-diameter laser beam and power of 5 W for 15 s was used, based on previous experiments. MC output was converted into absorbed energy, serving as input for ANSYS finite element heat transfer simulations of tissue temperatures over time. Convective heat transfer was simulated with contact cooling probe set at 0 °C. Thermal properties (κ,c,ρ) were assigned to each tissue layer. MATLAB code was used for Arrhenius integral thermal damage calculations. A temperature matrix was constructed from ANSYS output, and finite sum was incorporated to approximate Arrhenius integral calculations. Tissue damage properties (Ea,A) were used to compute Arrhenius sums. For the transvaginal approach, 37% of energy was absorbed in endopelvic fascia layer with 0.8% deposited beyond it. Peak temperature was 71°C, treatment zone was 0.8-mm-diameter, and almost all of 2.7-mm-thick vaginal wall was preserved. For transurethral approach, 18% energy was absorbed in endopelvic fascia with 0.3% deposited beyond it. Peak temperature was 80°C, treatment zone was 2.0-mm-diameter, and only 0.6 mm of 2.4-mm-thick urethral wall was preserved. A transvaginal approach is more feasible than transurethral approach for laser treatment of SUI.

  18. Laser-induced damage of fused silica optics at 355 nm due to backward stimulated Brillouin scattering: experimental and theoretical results.

    PubMed

    Lamaignère, Laurent; Gaudfrin, Kévin; Donval, Thierry; Natoli, Jeanyves; Sajer, Jean-Michel; Penninckx, Denis; Courchinoux, Roger; Diaz, Romain

    2018-04-30

    Forward pump pulses with nanosecond duration are able to generate an acoustic wave via electrostriction through a few centimeters of bulk silica. Part of the incident energy is then scattered back on this sound wave, creating a backward Stokes pulse. This phenomenon known as stimulated Brillouin scattering (SBS) might induce first energy-loss, variable change of the temporal waveform depending on the location in the spatial profile making accurate metrology impossible, and moreover it might also initiate front surface damage making the optics unusable. Experiments performed on thick fused silica optics at 355 nm with single longitudinal mode pulses allowed us to detect, observe and quantify these backward pulses. Experimental results are first compared to theoretical calculations in order to strengthen our confidence in metrology. On this basis a phase-modulator has been implemented on the continuous-wave seeders of the lasers leading to pulses with a wide spectrum that suppress SBS and do not exhibit temporal overshoots that also reduce Kerr effects. The developed set-ups are used to check the reduction of the backward stimulated Brillouin scattering and they allow measuring with accuracy the rear surface damage of thick fused silica optics.

  19. Impact damage visualization in a honeycomb composite panel through laser inspection using zero-lag cross-correlation imaging condition.

    PubMed

    Girolamo, Donato; Chang, Huan-Yu; Yuan, Fuh-Gwo

    2018-07-01

    A fully non-contact laser-based nondestructive inspection (NDI) system is developed to detect and visualize damage in structures. The study focuses on the size quantification and characterization of a barely visible impact damage (BVID) in a honeycomb composite panel. The hardware consists of a Q-switched Nd:YAG pulse laser that probes the panel by generating broadband guided waves via thermo-elastic expansion. The laser, in combination with a set of galvano-mirrors is used to raster scan over a two-dimensional surface covering the damaged region of an impacted quasi-isotropic [60/0/-60] s honeycomb composite panel. The out-of-plane velocities are measured at a fixed location normal to the surface by a laser Doppler vibrometer (LDV). An ultrasonic full wavefield assembled from the three-dimensional space-time data matrix in the interrogated area is first acquired and then processed for imaging the impacted damage area. A wavenumber filtering technique in terms of wave vectors is applied to distinguish the forward and backward wavefields in the wavenumber-frequency domain. A zero-lag cross correlation (ZLCC) imaging condition is then employed in the space-frequency domain for damage imaging. The ZLCC imaging condition consists of cross correlating the incident and reflected wavefields in the entire scanned region. The condition not only images the damage boundary between incident and reflected waves outside the damage region but also, for longer time windows, enables to capture the momentary standing waves formed within the damaged region. The ZLCC imaging condition imaged two delaminated region: a main delamination, which was a skewed elliptic with major and minor axis lengths roughly 17 mm and 10 mm respectively, and a secondary delamination region approximately 6 mm by 4 mm, however, which can only be shown at higher frequency range around 80-95 kHz. To conclude, the ZLCC results were in very good agreement with ultrasonic C-scan and X-ray computed

  20. Measuring single-shot, picosecond optical damage threshold in Ge, Si, and sapphire with a 5.1-μm laser

    DOE PAGES

    Agustsson, R.; Pogorelsky, I.; Arab, E.; ...

    2015-11-18

    Optical photonic structures driven by picosecond, GW-class lasers are emerging as promising novel sources of electron beams and high quality X-rays. Due to quadratic dependence on wavelength of the laser ponderomotive potential, the performance of such sources scales very favorably towards longer drive laser wavelengths. However, to take full advantage of photonic structures at mid-IR spectral region, it is important to determine optical breakdown limits of common optical materials. To this end, an experimental study was carried out at a wavelength of 5 µm, using a frequency-doubled CO 2 laser source, with 5 ps pulse length. Single-shot optical breakdowns weremore » detected and characterized at different laser intensities, and damage threshold values of 0.2, 0.3, and 7.0 J/cm 2, were established for Ge, Si, and sapphire, respectively. As a result, the measured damage threshold values were stable and repeatable within individual data sets, and across varying experimental conditions.« less

  1. Measuring single-shot, picosecond optical damage threshold in Ge, Si, and sapphire with a 5.1-μm laser

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Agustsson, R.; Pogorelsky, I.; Arab, E.

    Optical photonic structures driven by picosecond, GW-class lasers are emerging as promising novel sources of electron beams and high quality X-rays. Due to quadratic dependence on wavelength of the laser ponderomotive potential, the performance of such sources scales very favorably towards longer drive laser wavelengths. However, to take full advantage of photonic structures at mid-IR spectral region, it is important to determine optical breakdown limits of common optical materials. To this end, an experimental study was carried out at a wavelength of 5 µm, using a frequency-doubled CO 2 laser source, with 5 ps pulse length. Single-shot optical breakdowns weremore » detected and characterized at different laser intensities, and damage threshold values of 0.2, 0.3, and 7.0 J/cm 2, were established for Ge, Si, and sapphire, respectively. As a result, the measured damage threshold values were stable and repeatable within individual data sets, and across varying experimental conditions.« less

  2. Low damage electrical modification of 4H-SiC via ultrafast laser irradiation

    NASA Astrophysics Data System (ADS)

    Ahn, Minhyung; Cahyadi, Rico; Wendorf, Joseph; Bowen, Willie; Torralva, Ben; Yalisove, Steven; Phillips, Jamie

    2018-04-01

    The electrical properties of 4H-SiC under ultrafast laser irradiation in the low fluence regime (<0.50 J/cm2) are presented. The appearance of high spatial frequency laser induced periodic surface structures is observed at a fluence near 0.25 J/cm2 and above, with variability in environments like in air, nitrogen, and a vacuum. In addition to the formation of periodic surface structures, ultrafast laser irradiation results in possible surface oxidation and amorphization of the material. Lateral conductance exhibits orders of magnitude increase, which is attributed to either surface conduction or modification of electrical contact properties, depending on the initial material conductivity. Schottky barrier formation on ultrafast laser irradiated 4H-SiC shows an increase in the barrier height, an increase in the ideality factor, and sub-bandgap photovoltaic responses, suggesting the formation of photo-active point defects. The results suggest that the ultrafast laser irradiation technique provides a means of engineering spatially localized structural and electronic modification of wide bandgap materials such as 4H-SiC with relatively low surface damage via low temperature processing.

  3. Damage thresholds of silica fibers in holmium:YAG laser energy delivery for medical applications

    NASA Astrophysics Data System (ADS)

    Marolda, Matthew D.; Perrault, Donald F., Jr.; Pankratov, Michail M.; Shapshay, Stanley M.

    1993-07-01

    Pulsed Holmium:YAG (Ho:YAG) laser has been approved for some clinical applications and is under investigation for others. There is little published evidence on the durability or damage parameters for the fibers used in delivering energy from pulsed Ho:YAG laser. This study makes an initial attempt to investigate the damage threshold of different silica fibers under various conditions. Three types of fibers supplied by different manufacturers underwent laboratory testing. The overall finding of the study is that a new `perfect' fiber sustains no damage when fired without a target in air or in saline at energies up to 1.5 J/pulse and repetition rate up to 10 Hz. This study suggests that one may need to chose a fiber according to the clinical procedure to be performed: in cases where only soft tissue is to be manipulated - - any fiber may fare well, in cases where bone or calcified tissue is to be lased -- one may need fiber with aluminized or other hard coating. We also conclude that only professional refinishing with the removal of all exposed core-cladding material can insure trouble free performance.

  4. In situ mitigation of subsurface and peripheral focused ion beam damage via simultaneous pulsed laser heating

    DOE PAGES

    Stanford, Michael G.; Lewis, Brett B.; Iberi, Vighter O.; ...

    2016-02-16

    Focused helium and neon ion (He(+)/Ne(+) ) beam processing has recently been used to push resolution limits of direct-write nanoscale synthesis. The ubiquitous insertion of focused He(+) /Ne(+) beams as the next-generation nanofabrication tool-of-choice is currently limited by deleterious subsurface and peripheral damage induced by the energetic ions in the underlying substrate. The in situ mitigation of subsurface damage induced by He(+)/Ne(+) ion exposures in silicon via a synchronized infrared pulsed laser-assisted process is demonstrated. The pulsed laser assist provides highly localized in situ photothermal energy which reduces the implantation and defect concentration by greater than 90%. The laser-assisted exposuremore » process is also shown to reduce peripheral defects in He(+) patterned graphene, which makes this process an attractive candidate for direct-write patterning of 2D materials. In conclusion, these results offer a necessary solution for the applicability of high-resolution direct-write nanoscale material processing via focused ion beams.« less

  5. Reduction of the 355-nm laser-induced damage initiators by removing the subsurface cracks in fused silica

    NASA Astrophysics Data System (ADS)

    Yang, Minghong; Qi, Hongji; Zhao, Yuanan; Yi, Kui

    2012-01-01

    The 355 nm laser-induced damage thresholds (LIDTs) of polished fused silica with and without the residual subsurface cracks were explored. HF based wet etching and magnetorheological finishing was used to remove the subsurface cracks. To isolate the effect of subsurface cracks, chemical leaching was used to eliminate the photoactive impurities in the polishing layer. Results show that the crack number density decreased from~103 to <1cm-2, and the LIDT was improved as high as 2.8-fold with both the subsurface cracks and the polishing layer being removed. Subsurface cracks play a significant role in laser damage at fluencies between 15~31 J/cm2 (355nm, 8ns). HF Etching of the cracks was shown to increase the damage performance as nearly high as that of the samples in which subsurface cracks are well controlled.

  6. Link between mechanical strength and laser damage threshold for antireflective coating made by sol-gel

    NASA Astrophysics Data System (ADS)

    Avice, J.; Piombini, H.; Boscher, C.; Belleville, P.; Vaudel, G.; Brotons, G.; Ruello, P.; Gusev, V.

    2017-11-01

    The MegaJoule Laser (LMJ) for inertial confinement fusion experiments is currently in operation at CEA-CESTA in France. All the lenses are coated by an antireflective (AR) layer to optimize the light power transmission. This AR layer is manufactured by sol-gel process, a soft chemical process, associated with a liquid phase coating technique to realize thin film of metal oxide. These optical components are hardened into ammoniac vapors in order to mechanically reinforce the AR coating and to make them more handling. This hardening induces a thickness reduction of the layer so an increase of the stiffness and sometimes a crazing of the layer. As these optical components undergo a high-power laser beam, so, it is important to verify if the AR properties (optical and mechanical) influence the value of the threshold laser damage. A series of coated samples have been manufactured having variable elastic moduli to discuss this point. In that purpose, a homemade Laser Induced Damage Threshold (LIDT) setup has been developed to test the layers under laser flux. We describe the used methods and different results are given. Preliminary results obtained on several coated samples with variable elastic moduli are presented. We show that whatever are the elastic stiffness of the AR coating, an overall decrease of the threshold appears with no noticeable effect of the mechanical properties of the AR coatings. Some possible explanations are given.

  7. Laser-induced damage in optical materials: sixteenth ASTM symposium.

    PubMed

    Bennett, H E; Guenther, A H; Milam, D; Newnam, B E

    1987-03-01

    The Sixteenth Annual Symposium on Optical Materials for High Power Lasers (Boulder Damage Symposium) was held at the National Bureau of Standards in Boulder, CO, 15-17 Oct. 1984. The Symposium was held under the auspices of ASTM Committee F-1, Subcommittee on Laser Standards, with the joint sponsorship of NBS, the Defense Advanced Research Project Agency, the Department of Energy, the Office of Naval Research, and the Air Force Office of Scientific Research. Approximately 180 scientists attended the Symposium, including representatives from England, France, The Netherlands, Scotland, and West Germany. The Symposium was divided into sessions concerning Materials and Measurements, Mirrors and Surfaces, Thin Films, and Fundamental Mechanisms. As in previous years, the emphasis of the papers presented at the Symposium was directed toward new frontiers and new developments. Particular emphasis was given to materials for high-power apparatus. The wavelength range of prime interest was from 10.6,microm to the UV region. Highlights included surface characterization, thin-film-substrate boundaries, and advances in fundamental laser-matter threshold interactions and mechanisms. Harold E. Bennett of the U.S. Naval Weapons Center, Arthur H. Guenther of the U.S. Air Force Weapons Laboratory, David Milam of the Lawrence Livermore National Laboratory, and Brian E. Newnam of the Los Alamos National Laboratory were cochairmen of the Symposium.

  8. Optics Recycle Loop Strategy for NIF Operations above UV Laser-Induced Damage Threshold

    DOE PAGES

    Spaeth, M. L.; Wegner, P. J.; Suratwala, T. I.; ...

    2017-03-23

    The National Ignition Facility (NIF) at Lawrence Livermore National Laboratory (LLNL) houses the world’s largest laser system, composed of 192 individual, 40-cm-aperture beamlines. The NIF laser routinely operates at ultraviolet (UV) fluences above 8 J/cm 2, more than twice the (3ω only) damage threshold of commercially available UV-grade fused silica. NIF is able to maintain such high fluence operation by using an optics recycling loop strategy. Successful operation of the loop relies on a number of technologies specifically developed for NIF. One of the most important is the capability developed by LLNL and their vendors for producing highly damage-resistant optics.more » Other technologies developed for the optics recycle loop raise the operating point of NIF by keeping damage growth in check. LLNL has demonstrated the capability to sustain UV fused silica optic recycling rates of up to 40 optics per week. The optics are ready for reinstallation after a 3-week trip through a recycle loop where the damage state of each optic is assessed and repaired. The impact of the optics recycle loop has been profound, allowing the experimental program to routinely employ energies and fluences that would otherwise have been unachievable. Without the recycle loop, it is likely that the NIF fluence would need to be kept below the UV threshold for damage growth, ~4 J/cm 2, thus keeping the energy delivered to the target significantly below 1 MJ. With the recycle loop implemented during the National Ignition Campaign, NIF can routinely deliver >1.8 MJ on target, an increase in operational capability of more than 100%. Finally, in this paper, the enabling technological advances, optical performance, and operational capability implications of the optics recycle loop are discussed.« less

  9. Optics Recycle Loop Strategy for NIF Operations above UV Laser-Induced Damage Threshold

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Spaeth, M. L.; Wegner, P. J.; Suratwala, T. I.

    The National Ignition Facility (NIF) at Lawrence Livermore National Laboratory (LLNL) houses the world’s largest laser system, composed of 192 individual, 40-cm-aperture beamlines. The NIF laser routinely operates at ultraviolet (UV) fluences above 8 J/cm 2, more than twice the (3ω only) damage threshold of commercially available UV-grade fused silica. NIF is able to maintain such high fluence operation by using an optics recycling loop strategy. Successful operation of the loop relies on a number of technologies specifically developed for NIF. One of the most important is the capability developed by LLNL and their vendors for producing highly damage-resistant optics.more » Other technologies developed for the optics recycle loop raise the operating point of NIF by keeping damage growth in check. LLNL has demonstrated the capability to sustain UV fused silica optic recycling rates of up to 40 optics per week. The optics are ready for reinstallation after a 3-week trip through a recycle loop where the damage state of each optic is assessed and repaired. The impact of the optics recycle loop has been profound, allowing the experimental program to routinely employ energies and fluences that would otherwise have been unachievable. Without the recycle loop, it is likely that the NIF fluence would need to be kept below the UV threshold for damage growth, ~4 J/cm 2, thus keeping the energy delivered to the target significantly below 1 MJ. With the recycle loop implemented during the National Ignition Campaign, NIF can routinely deliver >1.8 MJ on target, an increase in operational capability of more than 100%. Finally, in this paper, the enabling technological advances, optical performance, and operational capability implications of the optics recycle loop are discussed.« less

  10. Laser injury and in vivo multimodal imaging using a mouse model

    NASA Astrophysics Data System (ADS)

    Pocock, Ginger M.; Boretsky, Adam; Gupta, Praveena; Oliver, Jeff W.; Motamedi, Massoud

    2011-03-01

    Balb/c wild type mice were used to perform in vivo experiments of laser-induced thermal damage to the retina. A Heidelberg Spectralis HRA confocal scanning laser ophthalmoscope with a spectral domain optical coherence tomographer was used to obtain fundus and cross-sectional images of laser induced injury in the retina. Sub-threshold, threshold, and supra-threshold lesions were observed using optical coherence tomography (OCT), infrared reflectance, red-free reflectance, fluorescence angiography, and autofluorescence imaging modalities at different time points post-exposure. Lesions observed using all imaging modalities, except autofluorescence, were not visible immediately after exposure but did resolve within an hour and grew in size over a 24 hour period. There was a decrease in fundus autofluorescence at exposure sites immediately following exposure that developed into hyper-fluorescence 24-48 hours later. OCT images revealed threshold damage that was localized to the RPE but extended into the neural retina over a 24 hour period. Volumetric representations of the mouse retina were created to visualize the extent of damage within the retina over a 24 hour period. Multimodal imaging provides complementary information regarding damage mechanisms that may be used to quantify the extent of the damage as well as the effectiveness of treatments without need for histology.

  11. Approach to quantify human dermal skin aging using multiphoton laser scanning microscopy

    NASA Astrophysics Data System (ADS)

    Puschmann, Stefan; Rahn, Christian-Dennis; Wenck, Horst; Gallinat, Stefan; Fischer, Frank

    2012-03-01

    Extracellular skin structures in human skin are impaired during intrinsic and extrinsic aging. Assessment of these dermal changes is conducted by subjective clinical evaluation and histological and molecular analysis. We aimed to develop a new parameter for the noninvasive quantitative determination of dermal skin alterations utilizing the high-resolution three-dimensional multiphoton laser scanning microscopy (MPLSM) technique. To quantify structural differences between chronically sun-exposed and sun-protected human skin, the respective collagen-specific second harmonic generation and the elastin-specific autofluorescence signals were recorded in young and elderly volunteers using the MPLSM technique. After image processing, the elastin-to-collagen ratio (ELCOR) was calculated. Results show that the ELCOR parameter of volar forearm skin significantly increases with age. For elderly volunteers, the ELCOR value calculated for the chronically sun-exposed temple area is significantly augmented compared to the sun-protected upper arm area. Based on the MPLSM technology, we introduce the ELCOR parameter as a new means to quantify accurately age-associated alterations in the extracellular matrix.

  12. Analysis of laser damage tests on coatings designed for broad bandwidth high reflection of femtosecond pulses

    DOE PAGES

    Bellum, John Curtis; Winstone, Trevor; Lamaignere, Laurent; ...

    2016-08-25

    We designed an optical coating based on TiO 2/SiO 2 layer pairs for broad bandwidth high reflection (BBHR) at 45-deg angle of incidence (AOI), P polarization of femtosecond (fs) laser pulses of 900-nm center wavelength, and produced the coatings in Sandia’s large optics coater by reactive, ion-assisted e-beam evaporation. This paper reports on laser-induced damage threshold (LIDT) tests of these coatings. The broad HR bands of BBHR coatings pose challenges to LIDT tests. An ideal test would be in a vacuum environment appropriate to a high energy, fs-pulse, petawatt-class laser, with pulses identical to its fs pulses. Short of thismore » would be tests over portions of the HR band using nanosecond or sub-picosecond pulses produced by tunable lasers. Such tests could, e.g., sample 10-nm-wide wavelength intervals with center wavelengths tunable over the broad HR band. Alternatively, the coating’s HR band could be adjusted by means of wavelength shifts due to changing the AOI of the LIDT tests or due to the coating absorbing moisture under ambient conditions. In conclusion, we had LIDT tests performed on the BBHR coatings at selected AOIs to gain insight into their laser damage properties and analyze how the results of the different LIDT tests compare.« less

  13. Analysis of laser damage tests on coatings designed for broad bandwidth high reflection of femtosecond pulses

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bellum, John Curtis; Winstone, Trevor; Lamaignere, Laurent

    We designed an optical coating based on TiO 2/SiO 2 layer pairs for broad bandwidth high reflection (BBHR) at 45-deg angle of incidence (AOI), P polarization of femtosecond (fs) laser pulses of 900-nm center wavelength, and produced the coatings in Sandia’s large optics coater by reactive, ion-assisted e-beam evaporation. This paper reports on laser-induced damage threshold (LIDT) tests of these coatings. The broad HR bands of BBHR coatings pose challenges to LIDT tests. An ideal test would be in a vacuum environment appropriate to a high energy, fs-pulse, petawatt-class laser, with pulses identical to its fs pulses. Short of thismore » would be tests over portions of the HR band using nanosecond or sub-picosecond pulses produced by tunable lasers. Such tests could, e.g., sample 10-nm-wide wavelength intervals with center wavelengths tunable over the broad HR band. Alternatively, the coating’s HR band could be adjusted by means of wavelength shifts due to changing the AOI of the LIDT tests or due to the coating absorbing moisture under ambient conditions. In conclusion, we had LIDT tests performed on the BBHR coatings at selected AOIs to gain insight into their laser damage properties and analyze how the results of the different LIDT tests compare.« less

  14. Impact damage detection in sandwich composite structures using Lamb waves and laser vibrometry

    NASA Astrophysics Data System (ADS)

    Lamboul, B.; Passilly, B.; Roche, J.-M.; Osmont, D.

    2013-01-01

    This experimental study explores the feasibility of impact damage detection in composite sandwich structures using Lamb wave excitation and signals acquired with a laser Doppler vibrometer. Energy maps are computed from the transient velocity wave fields and used to highlight defect areas in impacted coupons of foam core and honeycomb core sandwich materials. The technique performs well for the detection of barely visible damage in this type of material, and is shown to be robust in the presence of wave reverberation. Defect extent information is not always readily retrieved from the obtained defect signatures, which depend on the wave - defect interaction mechanisms.

  15. Targeting telomere-containing chromosome ends with a near-infrared femtosecond laser to study the activation of the DNA damage response and DNA damage repair pathways

    PubMed Central

    Silva, Bárbara Alcaraz; Stambaugh, Jessica R.

    2013-01-01

    Abstract. Telomeres are at the ends of chromosomes. Previous evidence suggests that laser-induced deoxyribose nucleic acid (DNA) breaks at chromosome ends during anaphase results in delayed cytokinesis. A possible explanation for this delay is that the DNA damage response (DDR) mechanism has been activated. We describe a live imaging method to study the effects of DDR activation following focal point near-infrared femtosecond laser microirradiation either at a single chromosome end or at a chromosome arm in mitotic anaphase cells. Laser microirradiation is used in combination with dual fluorescent labeling to monitor the co-localization of double-strand break marker γH2AX along with the DDR factors in PtK2 (Potorous tridactylus) cells. Laser-induced DNA breaks in chromosome ends as well as in chromosome arms results in recruitment of the following: poly(ADP-ribose) polymerase 1, checkpoint sensors (p-Chk1, p-Chk2), DNA repair protein Ku70/Ku80, and proliferating cell nuclear antigen. However, phosphorylated p53 at serine 15 is detected only at chromosome ends and not at chromosome arms. Full activation of DDR on damaged chromosome ends may explain previously published results that showed the delay of cytokinesis. PMID:24064949

  16. Design and comparison of laser windows for high-power lasers

    NASA Astrophysics Data System (ADS)

    Niu, Yanxiong; Liu, Wenwen; Liu, Haixia; Wang, Caili; Niu, Haisha; Man, Da

    2014-11-01

    High-power laser systems are getting more and more widely used in industry and military affairs. It is necessary to develop a high-power laser system which can operate over long periods of time without appreciable degradation in performance. When a high-energy laser beam transmits through a laser window, it is possible that the permanent damage is caused to the window because of the energy absorption by window materials. So, when we design a high-power laser system, a suitable laser window material must be selected and the laser damage threshold of the window must be known. In this paper, a thermal analysis model of high-power laser window is established, and the relationship between the laser intensity and the thermal-stress field distribution is studied by deducing the formulas through utilizing the integral-transform method. The influence of window radius, thickness and laser intensity on the temperature and stress field distributions is analyzed. Then, the performance of K9 glass and the fused silica glass is compared, and the laser-induced damage mechanism is analyzed. Finally, the damage thresholds of laser windows are calculated. The results show that compared with K9 glass, the fused silica glass has a higher damage threshold due to its good thermodynamic properties. The presented theoretical analysis and simulation results are helpful for the design and selection of high-power laser windows.

  17. Laser-induced damage in biological tissue: Role of complex and dynamic optical properties of the medium

    NASA Astrophysics Data System (ADS)

    Ahmed, Elharith M.

    Since its invention in the early 1960's, the laser has been used as a tool for surgical, therapeutic, and diagnostic purposes. To achieve maximum effectiveness with the greatest margin of safety it is important to understand the mechanisms of light propagation through tissue and how that light affects living cells. Lasers with novel output characteristics for medical and military applications are too often implemented prior to proper evaluation with respect to tissue optical properties and human safety. Therefore, advances in computational models that describe light propagation and the cellular responses to laser exposure, without the use of animal models, are of considerable interest. Here, a physics-based laser-tissue interaction model was developed to predict the spatial and temporal temperature and pressure rise during laser exposure to biological tissues. Our new model also takes into account the dynamic nature of tissue optical properties and their impact on the induced temperature and pressure profiles. The laser-induced retinal damage is attributed to the formation of microbubbles formed around melanosomes in the retinal pigment epithelium (RPE) and the damage mechanism is assumed to be photo-thermal. Selective absorption by melanin creates these bubbles that expand and collapse around melanosomes, destroying cell membranes and killing cells. The Finite Element (FE) approach taken provides suitable ground for modeling localized pigment absorption which leads to a non-uniform temperature distribution within pigmented cells following laser pulse exposure. These hot-spots are sources for localized thermo-elastic stresses which lead to rapid localized expansions that manifest themselves as microbubbles and lead to microcavitations. Model predictions for the interaction of lasers at wavelengths of 193, 694, 532, 590, 1314, 1540, 2000, and 2940 nm with biological tissues were generated and comparisons were made with available experimental data for the retina

  18. Multiscale analysis: a way to investigate laser damage precursors in materials for high power applications at nanosecond pulse duration

    NASA Astrophysics Data System (ADS)

    Natoli, J. Y.; Wagner, F.; Ciapponi, A.; Capoulade, J.; Gallais, L.; Commandré, M.

    2010-11-01

    The mechanism of laser induced damage in optical materials under high power nanosecond laser irradiation is commonly attributed to the presence of precursor centers. Depending on material and laser source, the precursors could have different origins. Some of them are clearly extrinsic, such as impurities or structural defects linked to the fabrication conditions. In most cases the center size ranging from sub-micrometer to nanometer scale does not permit an easy detection by optical techniques before irradiation. Most often, only a post mortem observation of optics permits to proof the local origin of breakdown. Multi-scale analyzes by changing irradiation beam size have been performed to investigate the density, size and nature of laser damage precursors. Destructive methods such as raster scan, laser damage probability plot and morphology studies permit to deduce the precursor densities. Another experimental way to get information on nature of precursors is to use non destructive methods such as photoluminescence and absorption measurements. The destructive and non destructive multiscale studies are also motivated for practical reasons. Indeed LIDT studies of large optics as those used in LMJ or NIF projects are commonly performed on small samples and with table top lasers whose characteristics change from one to another. In these conditions, it is necessary to know exactly the influence of the different experimental parameters and overall the spot size effect on the final data. In this paper, we present recent developments in multiscale characterization and results obtained on optical coatings (surface case) and KDP crystal (bulk case).

  19. Laser-induced damage thresholds of gold, silver and their alloys in air and water

    NASA Astrophysics Data System (ADS)

    Starinskiy, Sergey V.; Shukhov, Yuri G.; Bulgakov, Alexander V.

    2017-02-01

    The nanosecond-laser-induced damage thresholds of gold, silver and gold-silver alloys of various compositions in air and water have been measured for single-shot irradiation conditions. The experimental results are analyzed theoretically by solving the heat flow equation for the samples irradiated in air and in water taking into account vapor nucleation at the solid-water interface. The damage thresholds of Au-Ag alloys are systematically lower than those for pure metals, both in air and water that is explained by lower thermal conductivities of the alloys. The thresholds measured in air agree well with the calculated melting thresholds for all samples. The damage thresholds in water are found to be considerably higher, by a factor of ∼1.5, than the corresponding thresholds in air. This cannot be explained, in the framework of the used model, neither by the conductive heat transfer to water nor by the vapor pressure effect. Possible reasons for the high damage thresholds in water such as scattering of the incident laser light by the vapor-liquid interface and the critical opalescence in the superheated water are suggested. Optical pump-probe measurements have been performed to study the reflectance dynamics of the surface irradiated in air and water. Comparison of the transient reflectance signal with the calculated nucleation dynamics provides evidence that the both suggested scattering mechanisms are likely to occur during metal ablation in water.

  20. A quantitative damage imaging technique based on enhanced CCRTM for composite plates using 2D scan

    NASA Astrophysics Data System (ADS)

    He, Jiaze; Yuan, Fuh-Gwo

    2016-10-01

    A two-dimensional (2D) non-contact areal scan system was developed to image and quantify impact damage in a composite plate using an enhanced zero-lag cross-correlation reverse-time migration (E-CCRTM) technique. The system comprises a single piezoelectric wafer mounted on the composite plate and a laser Doppler vibrometer (LDV) for scanning a region in the vicinity of the PZT to capture the scattered wavefield. The proposed damage imaging technique takes into account the amplitude, phase, geometric spreading, and all of the frequency content of the Lamb waves propagating in the plate; thus, a reflectivity coefficients of the delamination is calculated and potentially related to damage severity. Comparisons are made in terms of damage imaging quality between 2D areal scans and 1D line scans as well as between the proposed and existing imaging conditions. The experimental results show that the 2D E-CCRTM performs robustly when imaging and quantifying impact damage in large-scale composites using a single PZT actuator with a nearby areal scan using LDV.

  1. Irradiance enhancement and increased laser damage threshold in As₂S₃ moth-eye antireflective structures.

    PubMed

    Weiblen, R Joseph; Florea, Catalin M; Busse, Lynda E; Shaw, L Brandon; Menyuk, Curtis R; Aggarwal, Ishwar D; Sanghera, Jasbinder S

    2015-10-15

    It has been experimentally observed that moth-eye antireflective microstructures at the end of As2S3 fibers have an increased laser damage threshold relative to thin-film antireflective coatings. In this work, we computationally study the irradiance enhancement in As2S3 moth-eye antireflective microstructures in order to explain the increased damage threshold. We show that the irradiance enhancement occurs mostly on the air side of the interfaces and is minimal in the As2S3 material. We give a physical explanation for this behavior.

  2. BDS thin film damage competition

    NASA Astrophysics Data System (ADS)

    Stolz, Christopher J.; Thomas, Michael D.; Griffin, Andrew J.

    2008-10-01

    A laser damage competition was held at the 2008 Boulder Damage Symposium in order to determine the current status of thin film laser resistance within the private, academic, and government sectors. This damage competition allows a direct comparison of the current state-of-the-art of high laser resistance coatings since they are all tested using the same damage test setup and the same protocol. A normal incidence high reflector multilayer coating was selected at a wavelength of 1064 nm. The substrates were provided by the submitters. A double blind test assured sample and submitter anonymity so only a summary of the results are presented here. In addition to the laser resistance results, details of deposition processes, coating materials, and layer count will also be shared.

  3. Atomic layer deposition for fabrication of HfO2/Al2O3 thin films with high laser-induced damage thresholds.

    PubMed

    Wei, Yaowei; Pan, Feng; Zhang, Qinghua; Ma, Ping

    2015-01-01

    Previous research on the laser damage resistance of thin films deposited by atomic layer deposition (ALD) is rare. In this work, the ALD process for thin film generation was investigated using different process parameters such as various precursor types and pulse duration. The laser-induced damage threshold (LIDT) was measured as a key property for thin films used as laser system components. Reasons for film damaged were also investigated. The LIDTs for thin films deposited by improved process parameters reached a higher level than previously measured. Specifically, the LIDT of the Al2O3 thin film reached 40 J/cm(2). The LIDT of the HfO2/Al2O3 anti-reflector film reached 18 J/cm(2), the highest value reported for ALD single and anti-reflect films. In addition, it was shown that the LIDT could be improved by further altering the process parameters. All results show that ALD is an effective film deposition technique for fabrication of thin film components for high-power laser systems.

  4. Role of HfO 2/SiO 2 thin-film interfaces in near-ultraviolet absorption and pulsed laser damage

    DOE PAGES

    Papernov, Semyon; Kozlov, Alexei A.; Oliver, James B.; ...

    2016-07-15

    Here, the role of thin-film interfaces in the near-ultraviolet (near-UV) absorption and pulsed laser-induced damage was studied for ion-beam-sputtered and electron-beam-evaporated coatings comprised from HfO 2 and SiO 2 thin-film pairs. To separate contributions from the bulk of the film and from interfacial areas, absorption and damage threshold measurements were performed for a one-wave (355-nm wavelength) thick, HfO 2 single-layer film and for a film containing seven narrow HfO 2 layers separated by SiO 2 layers. The seven-layer film was designed to have a total optical thickness of HfO 2 layers, equal to one wave at 355 nm and anmore » E-field peak and average intensity similar to a single-layer HfO 2 film. Absorption in both types of films was measured using laser calorimetry and photothermal heterodyne imaging. The results showed a small contribution to total absorption from thin-film interfaces as compared to HfO 2 film material. The relevance of obtained absorption data to coating near-UV, nanosecond-pulse laser damage was verified by measuring the damage threshold and characterizing damage morphology. The results of this study revealed a higher damage resistance in the seven-layer coating as compared to the single-layer HfO 2 film in both sputtered and evaporated coatings. The results are explained through the similarity of interfacial film structure with structure formed during the codeposition of HfO 2 and SiO 2 materials.« less

  5. Diode laser (808 nm) applied to oral soft tissue lesions: a retrospective study to assess histopathological diagnosis and evaluate physical damage.

    PubMed

    Angiero, Francesca; Parma, Luisa; Crippa, Rolando; Benedicenti, Stefano

    2012-03-01

    The diode laser is today widely used in oral pathology to excise lesions; however, some controversy surrounds laser surgery, specifically the accuracy of pathological diagnosis and the control over thermal tissue damage. This study aimed to establish if physical damage induced by the diode laser could affect the histopathological diagnosis and to evaluate the damage caused to the resection margins. Between 2005 and 2010, at S. Gerardo Hospital, Milan, 608 cases of soft tissue lesions localized in the oral cavity (cheek, gingiva, buccal mucosa, tongue, and lips) were examined. Specimens were excised with an 808-nm diode laser, output 1.6-2.7 W, in continuous-wave mode with fibers of 320 μm. Specimens were fixed in 10% buffered formalin solution and examined separately under an optical microscope by two pathologists. In all of the specimens, changes to the epithelium, connective tissue and blood vessels, shape of incision damage, and overall width of modified tissues were evaluated. The data for specimens larger than 3 mm excised with the diode laser were not significant in terms of stromal changes or vascular stasis, while epithelial and stromal changes were significantly more frequent in specimens with a mean size below 3 mm; the diagnosis was not achievable in 46.15%. Our data show that the diode laser is a valid therapeutic instrument for excising oral lesions larger than 3 mm in diameter, but induces serious thermal effects in small lesions (mean size below 3 mm). However, from a clinical standpoint, it is suggested necessary that the specimens taken have in vivo a diameter of at least 5 mm in order to have a reliable reading of the histological sample.

  6. Wavelength and pulselength dependence of laser conditioning and bulk damage in doubler-cut KH2PO4

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Adams, J J; Bruere, J R; Bolourchi, M

    2005-10-28

    An experimental technique has been utilized to measure the variation of bulk damage scatter with damaging fluence in plates of KH{sub 2}PO{sub 4} (KDP) crystals. Bulk damage in unconditioned and laser-conditioned doubler-cut KDP crystals has been studied using 527 nm (2{omega}) light at pulselengths of 0.3-10 ns. It is found that there is less scatter due to damage at fixed fluence for longer pulselengths. In particular, there is {approx}4X increase in fluence for equivalent scatter for damage at 2{omega}, 10 ns as compared to 0.30 ns in unconditioned KDP. The results for the unconditioned and conditioned KDP show that formore » all the pulselengths the scatter due to the bulk damage is a strong function of the damaging fluence ({phi}{sup -5}). It is determined that the 2{omega} fluence pulselength-scaling for equivalent bulk damage scatter in unconditioned KDP varies as {tau}{sup 0.30{+-}0.11} and in 3{omega}, 3ns ramp-conditioned KDP varies as {tau}{sup 0.27{+-}0.14}. The effectiveness of 2{omega} and 3{omega} laser conditioning at pulselengths in the range of 0.30-23 ns for damage induced 2{omega}, 3 ns is analyzed in terms of scatter. For the protocols tested (i.e. peak conditioning irradiance, etc.), the 3{omega}, 300 ps conditioning to a peak fluence of 3 J/cm{sup 2} had the best performance under 2{omega}, 3 ns testing. The general trend in the performance of the conditioning protocols was shorter wavelength and shorter pulselength appear to produce better conditioning for testing at 2{omega}, 3 ns.« less

  7. Monitoring of Progressive Damage in Buildings Using Laser Scan Data

    NASA Astrophysics Data System (ADS)

    Puente, I.; Lindenbergh, R.; Van Natijne, A.; Esposito, R.; Schipper, R.

    2018-05-01

    Vulnerability of buildings to natural and man-induced hazards has become a main concern for our society. Ensuring their serviceability, safety and sustainability is of vital importance and the main reason for setting up monitoring systems to detect damages at an early stage. In this work, a method is presented for detecting changes from laser scan data, where no registration between different epochs is needed. To show the potential of the method, a case study of a laboratory test carried out at the Stevin laboratory of Delft University of Technology was selected. The case study was a quasi-static cyclic pushover test on a two-story high unreinforced masonry structure designed to simulate damage evolution caused by cyclic loading. During the various phases, we analysed the behaviour of the masonry walls by monitoring the deformation of each masonry unit. First a plane is fitted to the selected wall point cloud, consisting of one single terrestrial laser scan, using Principal Component Analysis (PCA). Second, the segmentation of individual elements is performed. Then deformations with respect to this plane model, for each epoch and specific element, are determined by computing their corresponding rotation and cloud-to-plane distances. The validation of the changes detected within this approach is done by comparison with traditional deformation analysis based on co-registered TLS point clouds between two or more epochs of building measurements. Initial results show that the sketched methodology is indeed able to detect changes at the mm level while avoiding 3D point cloud registration, which is a main issue in computer vision and remote sensing.

  8. Nanosecond laser-induced damage at different initial temperatures of Ta{sub 2}O{sub 5} films prepared by dual ion beam sputtering

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Xu, Cheng, E-mail: xucheng@cumt.edu.cn; Jia, Jiaojiao; Fan, Heliang

    2014-08-07

    Ta{sub 2}O{sub 5} films were deposited by dual ion beam sputtering method. The nanosecond laser-induced damage threshold (LIDT) at different initial temperatures and time of the films was investigated by an in situ high temperature laser-induced damage testing platform. It was shown that, when the initial temperature increased from 298 K to 383 K, the LIDT at 1064 nm and 12 ns significantly decreased by nearly 14%. Then the LIDT at 1064 nm and 12 ns decreased slower with the same temperature increment. Different damage morphologies were found at different initial temperatures. At low initial temperatures, it was the defects-isolated damage while at high initial temperaturesmore » it was the defects-combined damage. The theoretical calculations based on the defect-induced damage model revealed that both the significant increase of the highest temperature and the duration contributed to the different damage morphologies. With the initial temperature being increased, the thermal-stress coupling damage mechanism transformed gradually to the thermal dominant damage mechanism.« less

  9. An enhanced CCRTM (E-CCRTM) damage imaging technique using a 2D areal scan for composite plates

    NASA Astrophysics Data System (ADS)

    He, Jiaze; Yuan, Fuh-Gwo

    2016-04-01

    A two-dimensional (2-D) non-contact areal scan system was developed to image and quantify impact damage in a composite plate using an enhanced zero-lag cross-correlation reverse-time migration (E-CCRTM) technique. The system comprises a single piezoelectric actuator mounted on the composite plate and a laser Doppler vibrometer (LDV) for scanning a region to capture the scattered wavefield in the vicinity of the PZT. The proposed damage imaging technique takes into account the amplitude, phase, geometric spreading, and all of the frequency content of the Lamb waves propagating in the plate; thus, the reflectivity coefficients of the delamination can be calculated and potentially related to damage severity. Comparisons are made in terms of damage imaging quality between 2-D areal scans and linear scans as well as between the proposed and existing imaging conditions. The experimental results show that the 2-D E-CCRTM performs robustly when imaging and quantifying impact damage in large-scale composites using a single PZT actuator with a nearby areal scan using LDV.

  10. Laser targeted photo-occlusion of rat choroidal neovascularization without collateral damage.

    PubMed

    Nishiwaki, Hirokazu; Zeimer, Ran; Goldberg, Morton F; D'Anna, Salvatore A; Vinores, Stanley A; Grebe, Rhonda

    2002-02-01

    Laser targeted photo-occlusion (LTO) is a novel method being developed to treat choroidal neovascular membranes (CNV) in age-related and other macular degenerations. A photosensitive agent, encapsulated in heat-sensitive liposomes, is administered intravenously. A low power laser warms the targeted tissue and releases a bolus of photosensitizer. The photosensitizer is activated after it clears from the normal choriocapillaris but not from the CNV. Forty-five experimental CNV were induced in seven rats. Five weeks after LTO, complete occlusion was observed by laser targeted angiography (LTA) in 76% of treated CNV, and partial occlusion was found in the remaining 24%. The tissues outside the CNV but within the area treated by LTO showed no flow alteration and no dye leakage. All untreated CNV were patent on LTA at 5 weeks. Light microscopy and electron microscopy confirmed the results in treated and control lesions. Moreover, treated areas next to lesions showed normal photoreceptors, retinal pigment epithelium (RPE), Bruch's membrane and choriocapillaris. These results indicate that LTO may improve current photodynamic therapy by alleviating the need for repeated treatments and by avoiding the long-term risks associated with damage to the RPE and occlusion of normal choriocapillaries.

  11. Collateral damage-free debridement using 193nm ArF laser

    NASA Astrophysics Data System (ADS)

    Wynne, James J.; Felsenstein, Jerome M.; Trzcinski, Robert; Zupanski-Nielsen, Donna; Connors, Daniel P.

    2011-03-01

    Burn eschar and other necrotic areas of the skin and soft tissue are anhydrous compared to the underlying viable tissue. A 193 nm ArF excimer laser, emitting electromagnetic radiation at 6.4 eV at fluence exceeding the ablation threshold, will debride such necrotic areas. Because such radiation is strongly absorbed by aqueous chloride ions through the nonthermal process of electron photodetachment, debridement will cease when hydrated (with chloride ions) viable tissue is exposed, avoiding collateral damage to this tissue. Such tissue will be sterile and ready for further treatment, such as a wound dressing and/or a skin graft.

  12. Damage detection in composite panels based on mode-converted Lamb waves sensed using 3D laser scanning vibrometer

    NASA Astrophysics Data System (ADS)

    Pieczonka, Łukasz; Ambroziński, Łukasz; Staszewski, Wiesław J.; Barnoncel, David; Pérès, Patrick

    2017-12-01

    This paper introduces damage identification approach based on guided ultrasonic waves and 3D laser Doppler vibrometry. The method is based on the fact that the symmetric and antisymmetric Lamb wave modes differ in amplitude of the in-plane and out-of-plane vibrations. Moreover, the modes differ also in group velocities and normally they are well separated in time. For a given time window both modes can occur simultaneously only close to the wave source or to a defect that leads to mode conversion. By making the comparison between the in-plane and out-of-plane wave vector components the detection of mode conversion is possible, allowing for superior and reliable damage detection. Experimental verification of the proposed damage identification procedure is performed on fuel tank elements of Reusable Launch Vehicles designed for space exploration. Lamb waves are excited using low-profile, surface-bonded piezoceramic transducers and 3D scanning laser Doppler vibrometer is used to characterize the Lamb wave propagation field. The paper presents theoretical background of the proposed damage identification technique as well as experimental arrangements and results.

  13. A high accuracy femto-/picosecond laser damage test facility dedicated to the study of optical thin films

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mangote, B.; Gallais, L.; Zerrad, M.

    2012-01-15

    A laser damage test facility delivering pulses from 100 fs to 3 ps and designed to operate at 1030 nm is presented. The different details of its implementation and performances are given. The originality of this system relies the online damage detection system based on Nomarski microscopy and the use of a non-conventional energy detection method based on the utilization of a cooled CCD that offers the possibility to obtain the laser induced damage threshold (LIDT) with high accuracy. Applications of this instrument to study thin films under laser irradiation are presented. Particularly the deterministic behavior of the sub-picosecond damagemore » is investigated in the case of fused silica and oxide films. It is demonstrated that the transition of 0-1 damage probability is very sharp and the LIDT is perfectly deterministic at few hundreds of femtoseconds. The damage process in dielectric materials being the results of electronic processes, specific information such as the material bandgap is needed for the interpretation of results and applications of scaling laws. A review of the different approaches for the estimation of the absorption gap of optical dielectric coatings is conducted and the results given by the different methods are compared and discussed. The LIDT and gap of several oxide materials are then measured with the presented instrument: Al{sub 2}O{sub 3}, Nb{sub 2}O{sub 5}, HfO{sub 2}, SiO{sub 2}, Ta{sub 2}O{sub 5}, and ZrO{sub 2}. The obtained relation between the LIDT and gap at 1030 nm confirms the linear evolution of the threshold with the bandgap that exists at 800 nm, and our work expands the number of tested materials.« less

  14. U.S. National Committee proposed revision to the ISO Laser Damage Standard

    NASA Astrophysics Data System (ADS)

    Arenberg, Jonathan W.; Howland, Donna; Thomas, Michael; Turner, Trey; Bellum, John; Field, Ella; Carr, C. Wren; Shaffer, Gary; Brophy, Matthew; Krisiloff, Allen

    2017-11-01

    This paper reports on the fundamental idea behind a US National Committee, The Optics and Electro-Optics Standards Council (OEOSC) Task Force (TF) 7, proposal for a so-called Type 1 laser damage test procedure. A Type 1 test is designed to give a simple binary, pass or fail, result. Such tests are intended for the transactional type of damage testing typical of acceptance and quality control testing. As such is it intended for bulk of certification of optics for the ability to survive a given fluence, useful for manufacturers of optics and their customers, the system builders. At the root of the proposed method is the probability that an optic of area A will have R or less damage occurrences with a user specified probability P at test fluence Φ. This assessment is made by a survey of area and the observation of n events. The paper presents the derivation of probability of N or less damage sites on A given n events observed in area a. The paper concludes with the remaining steps to development of a useful test procedure based on the idea presented.

  15. Comparison of retina damage thresholds simulating the femtosecond-laser in situ keratomileusis (fs-LASIK) process with two laser systems in the CW- and fs-regime

    NASA Astrophysics Data System (ADS)

    Sander, M.; Minet, O.; Zabarylo, U.; Müller, M.; Tetz, M. R.

    2012-04-01

    The femtosecond-laser in situ keratomileusis procedure affords the opportunity to correct ametropia by cutting transparent corneal tissue with ultra-short laser pulses. Thereby the tissue cut is generated by a laser-induced optical breakdown in the cornea with ultra-short laser pulses in the near-infrared range. Compared to standard procedures such as photorefractive keratectomy and laser in-situ keratomileusis with the excimer laser, where the risk potential for the eye is low due to the complete absorption of ultraviolet irradiation from corneal tissue, only a certain amount of the pulse energy is deposited in the cornea during the fs-LASIK process. The remaining energy propagates through the eye and interacts with the retina and the strong absorbing tissue layers behind. The objective of the presented study was to determine and compare the retina damage thresholds during the fs-LASIK process simulated with two various laser systems in the CW- and fs-regime.

  16. Argon laser phototherapy could eliminate the damage effects induced by the ionizing radiation "gamma radiation" in irradiated rabbits.

    PubMed

    Abdul-Aziz, Karolin Kamel; Tuorkey, M J

    2010-04-02

    The ionizing radiations could be taken in considerate as an integral part in our life, since, living organisms are actually exposed to a constant shower of ionizing radiations whether from the natural or artificial resources. The radio-protective efficiency of several chemicals has been confirmed in animal trails, whereas, due to their accumulative toxicity, their clinical utility is limited. Therefore, we aimed in the present work to investigate the possibility of using argon laser to recuperate the damaged tissues due to exposing to the ionizing radiation. The rabbits were used in this study, and they were designed as control, gamma irradiated, laser, and gamma plus laser groups. Lipid peroxidation, reduced glutathione (GSH), glutathione peroxidase (GSH-Px) and glucose-6-phosphate dehydrogenase (G-6-PD) in blood and liver were evaluated. As well as, the level of protein thiol was evaluated in the plasma among each group. Results of this study revealed the potential therapeutic performance of the treatment by laser argon to decline the damaging effect of the ionized radiation whether at systematic or local levels. In conclusion, argon laser therapy appears propitious protective effect against the hazard effects of gamma radiation. Copyright 2010 Elsevier B.V. All rights reserved.

  17. Effect of hydrogen concentration in conventional and IAD coatings on the absorption and laser-induced damage at 10.6 μm

    NASA Astrophysics Data System (ADS)

    Rahe, Manfred; Ristau, Detlev; Schmidt, Holger

    1993-06-01

    In this paper, data of single layers of YbF3, BaF2, YF3, and NaF and multilayer coatings produced by conventional thermal evaporation (boat, e-beam) and ion assisted deposition (IAD) are compared. Hydrogen concentration depth profiling was performed using nuclear reaction analysis based on the reaction 1H(15N, (alpha) (gamma) )12C. Absorption was measured with the aid of a laser calorimeter and a cw CO2 laser. A computer-controlled test facility with a TEA CO2 laser was used for determining the 1-on-1 damage thresholds of the coatings. The results point out that the absorption and damage behavior of coatings for the CO2 laser wavelength are related to the total amount of species containing hydrogen. Most of the IAD coatings exhibit a lower hydrogen contamination than conventional thin films.

  18. Corneal thermal damage threshold dependence on the exposure duration for near-infrared laser radiation at 1319 nm

    NASA Astrophysics Data System (ADS)

    Wang, Jiarui; Jiao, Luguang; Chen, Hongxia; Yang, Zaifu; Hu, Xiangjun

    2016-01-01

    The corneal damage effects induced by 1319-nm transitional near-infrared laser have been investigated for years. However, the damage threshold dependence on exposure duration has not been revealed. The in vivo corneal damage thresholds (ED50s) were determined in New Zealand rabbits for 1319-nm laser radiation for exposure durations from 75 ms to 10 s. An additional corneal ED50 was determined at 1338 nm for a 5-ms exposure. The incident corneal irradiance diameter was fixed at 2 mm for all exposure conditions to avoid the influence of spot size on threshold. The ED50s given in terms of the corneal radiant exposure for exposure durations of 5 ms, 75 ms, 0.35 s, 2 s, and 10 s were 39.4, 51.5, 87.2, 156.3, and 311.1 J/cm2, respectively. The 39.4 J/cm2 was derived from the ED50 for 1338 nm (27.0 J/cm2). The ED50s for exposure durations of 75 ms to 10 s were correlated by a power law equation, ED50=128.9t0.36 in J/cm2, where t was the input in the unit of second, with correlation coefficient (R) of 0.997. Enough safe margins existed between the ED50s and the maximum permitted exposures from current laser safety standard.

  19. Dye-Assisted Laser Skin Closure with Pulsed Radiation: An In Vitro Study of Weld Strength and Thermal Damage

    NASA Astrophysics Data System (ADS)

    Fried, Nathaniel M.; Walsh, Joseph T.

    1998-10-01

    Previous laser skin welding studies have used continuous wave delivery of radiation. However, heat diffusion during irradiation prevents strong welds from being achieved without creating large zones of thermal damage. Previously published results indicate that a thermal damage zone in skin greater than 200 micrometers may prevent normal wound healing. We proposed that both strong welds and minimal thermal damage can be achieved by introducing a dye and delivering the radiation in a series of sufficiently short pulses. Two-cm-long incisions were made in guinea pig skin, in vitro. India ink and egg white (albumin) were applied to the wound edges to enhance radiation absorption and to close the wound, respectively. Continuous wave (cw), 1.06 micrometers , Nd:yttrium-aluminum-garnet laser radiation was scanned over the weld producing approximately 100 ms pulses. The cooling time between scans and the number of scans was varied. The thermal damage zone at the weld edges was measured using a transmission polarizing light microscope. The tensile strength of the welds was measured using a tensiometer. For pulsed welding and long cooling times between pulses (8 s), weld strengths of 2.4 +/- 0.9 kg/cm2 were measured, and lateral thermal damage at the epidermis was limited to 500 +/- 150 micrometers . With cw welding, comparable weld strengths produced 2700 +/- 300 micrometers of lateral thermal damage. The cw weld strengths were only 0.6 +/- 0.3 kg/cm2 for thermal damage zones comparable to pulsed welding.

  20. Spatially sculpted laser scissors for study of DNA damage and repair

    NASA Astrophysics Data System (ADS)

    Stephens, Jared; Mohanty, Samarendra K.; Genc, Suzanne; Kong, Xiangduo; Yokomori, Kyoko; Berns, Michael W.

    2009-09-01

    We present a simple and efficient method for controlled linear induction of DNA damage in live cells. By passing a pulsed laser beam through a cylindrical lens prior to expansion, an elongated elliptical beam profile is created with the ability to expose controlled linear patterns while keeping the beam and the sample stationary. The length and orientation of the beam at the sample plane were reliably controlled by an adjustable aperture and rotation of the cylindrical lens, respectively. Localized immunostaining by the DNA double strand break (DSB) markers phosphorylated H2AX (γH2AX) and Nbs1 in the nuclei of HeLa cells exposed to the ``line scissors'' was shown via confocal imaging. The line scissors method proved more efficient than the scanning mirror and scanning stage methods at induction of DNA DSB damage with the added benefit of having a greater potential for high throughput applications.

  1. Analysis of enamel surface damage after selective laser ablation of composite from tooth surfaces.

    PubMed

    Chan, Kenneth H; Hirasuna, Krista; Fried, Daniel

    2014-02-01

    Resin-based composites are used for many applications in dentistry. They are difficult to remove without damage to the underlying enamel since they adhere strongly and are color matched to the tooth. The objective of this study was to determine if an automated laser scanning system with spectral feedback could be used for selective removal of residual orthodontic composite from tooth surfaces with minimal damage to the underlying enamel. A CO 2 laser operating at a wavelength of 9.3 μm with a pulse duration of 10-15 μs and a pulse repetition rate of ~200 Hz was used to selectively remove composite from the buccal surfaces of extracted teeth. A spectral feedback system utilizing a miniature spectrometer was used to control the laser scanning system. Pulpal temperature measurements were performed during composite removal to determine if there was excessive heat accumulation. Conventional and digital microscopes were used to assess the amount of enamel lost during removal. The amount of enamel lost averaged between 20 and 25 μm for irradiation intensities from 3.8 to 4.2 J/cm 2 , respectively. An average maximum temperature rise of 1.9±1.5°C was recorded, with no teeth approaching the critical value of 5.5°C. The average time for composite removal from an area of 5 mm 2 was 19.3±4.1 s, fast enough for clinical feasibility. Residual composite can be rapidly removed from tooth surfaces using a CO 2 laser with spectral feedback, with minimal temperature rise within the pulp and with minimal loss of sound enamel.

  2. CO2 laser and plasma microjet process for improving laser optics

    DOEpatents

    Brusasco, Raymond M.; Penetrante, Bernardino M.; Butler, James A.; Grundler, Walter; Governo, George K.

    2003-09-16

    A optic is produced for operation at the fundamental Nd:YAG laser wavelength of 1.06 micrometers through the tripled Nd:YAG laser wavelength of 355 nanometers by the method of reducing or eliminating the growth of laser damage sites in the optics by processing the optics to stop damage in the optics from growing to a predetermined critical size. A system is provided of mitigating the growth of laser-induced damage in optics by virtue of very localized removal of glass and absorbing material.

  3. Luminescence in the fluoride-containing phosphate-based glasses: A possible origin of their high resistance to nanosecond pulse laser-induced damage

    PubMed Central

    Wang, Pengfei; Lu, Min; Gao, Fei; Guo, Haitao; Xu, Yantao; Hou, Chaoqi; Zhou, Zhiwei; Peng, Bo

    2015-01-01

    Fusion power offers the prospect of an almost inexhaustible source of energy for future generations. It was reported that fusion fuel gains exceeding unity on the National Ignition Facility (NIF) were achieved, but so far great deal of scientific and engineering challenges have to be overcome for realizing fusion power generation. There is a bottleneck for color-separation gratings in NIF and other similar inertial confinement fusion (ICF) lasers. Here we show a series of high performance phosphate-based glasses that can transmit the third harmonic frequency (3ω) laser light with high efficiency meanwhile filter the fundamental (1ω) and the second harmonic frequency (2ω) laser lights through direct absorption, and especially they exhibit excellent damage threshold induced by nanosecond pulse laser compared with that of the fused silica used in NIF. Yellowish-orange fluorescence emits during the laser-material interaction process, and it can be tailored through regulating the glass structure. Study on its structural origin suggests that the fluorescence emission is a key factor that conduces to the high laser-induced damage resistance of these glasses. The results also indicated the feasibility of utilizing these high performance glasses in novel color separation optics, allowing novel design for the final optics assembly in ICF lasers. PMID:25716328

  4. Luminescence in the fluoride-containing phosphate-based glasses: a possible origin of their high resistance to nanosecond pulse laser-induced damage.

    PubMed

    Wang, Pengfei; Lu, Min; Gao, Fei; Guo, Haitao; Xu, Yantao; Hou, Chaoqi; Zhou, Zhiwei; Peng, Bo

    2015-02-26

    Fusion power offers the prospect of an almost inexhaustible source of energy for future generations. It was reported that fusion fuel gains exceeding unity on the National Ignition Facility (NIF) were achieved, but so far great deal of scientific and engineering challenges have to be overcome for realizing fusion power generation. There is a bottleneck for color-separation gratings in NIF and other similar inertial confinement fusion (ICF) lasers. Here we show a series of high performance phosphate-based glasses that can transmit the third harmonic frequency (3ω) laser light with high efficiency meanwhile filter the fundamental (1ω) and the second harmonic frequency (2ω) laser lights through direct absorption, and especially they exhibit excellent damage threshold induced by nanosecond pulse laser compared with that of the fused silica used in NIF. Yellowish-orange fluorescence emits during the laser-material interaction process, and it can be tailored through regulating the glass structure. Study on its structural origin suggests that the fluorescence emission is a key factor that conduces to the high laser-induced damage resistance of these glasses. The results also indicated the feasibility of utilizing these high performance glasses in novel color separation optics, allowing novel design for the final optics assembly in ICF lasers.

  5. Co:MgF2 laser ablation of tissue: effect of wavelength on ablation threshold and thermal damage.

    PubMed

    Schomacker, K T; Domankevitz, Y; Flotte, T J; Deutsch, T F

    1991-01-01

    The wavelength dependence of the ablation threshold of a variety of tissues has been studied by using a tunable pulsed Co:MgF2 laser to determine how closely it tracks the optical absorption length of water. The Co:MgF2 laser was tuned between 1.81 and 2.14 microns, a wavelength region in which the absorption length varies by a decade. For soft tissues the ablation threshold tracks the optical absorption length; for bone there is little wavelength dependence, consistent with the low water content of bone. Thermal damage vs. wavelength was also studied for cornea and bone. Thermal damage to cornea has a weak wavelength dependence, while that to bone shows little wavelength dependence. Framing-camera pictures of the ablation of both cornea and liver show explosive removal of material, but differ as to the nature of the explosion.

  6. Quantifying the effect of finite spectral bandwidth on extinction coefficient of species in laser absorption spectroscopy

    NASA Astrophysics Data System (ADS)

    Singh, Manjeet; Singh, Jaswant; Singh, Baljit; Ghanshyam, C.

    2016-11-01

    The aim of this study is to quantify the finite spectral bandwidth effect on laser absorption spectroscopy for a wide-band laser source. Experimental analysis reveals that the extinction coefficient of an analyte is affected by the bandwidth of the spectral source, which may result in the erroneous conclusions. An approximate mathematical model has been developed for optical intensities having Gaussian line shape, which includes the impact of source's spectral bandwidth in the equation for spectroscopic absorption. This is done by introducing a suitable first order and second order bandwidth approximation in the Beer-Lambert law equation for finite bandwidth case. The derived expressions were validated using spectroscopic analysis with higher SBW on a test sample, Rhodamine B. The concentrations calculated using proposed approximation, were in significant agreement with the true values when compared with those calculated with conventional approach.

  7. An in vitro Corneal Model with a Laser Damage Threshold at 2 Micrometers That is Similar to That in the Rabbit

    DTIC Science & Technology

    2007-11-01

    Proceedings 3. DATES COVERED (From - To) June 2007- November 2007 4. TITLE AND SUBTITLE An In Vitro Corneal Model with a Laser Damage Threshold at 2...2-µm wavelength output of a thulium fiber laser with 4 mm beam diameter for 0.25 seconds in a thermally controlled environment and then assayed for...data in the literature. 15. SUBJECT TERMS corneal organotypic culture, laser , threshold, thermography, Probit 16. SECURITY CLASSIFICATION OF

  8. An Alternative Method of Evaluating 1540NM Exposure Laser Damage using an Optical Tissue Phantom

    DTIC Science & Technology

    2006-11-01

    experimentation at this wavelength. Most experiments have been done using Yucatan and Yorkshire pig skin since it is very similar to human skin. Alexei...3.82 Guinea Pig 9 3.0 Domestic Pig - (Lukashev) 5, 6 3.2 Yucatan Mini-Pig (Zohner) 22 6.1 Figure 5. Laser exposure damage (8.39 J/cm 2) to resin, viewed

  9. Study on fibre laser machining quality of plain woven CFRP laminates

    NASA Astrophysics Data System (ADS)

    Li, Maojun; Li, Shuo; Yang, Xujing; Zhang, Yi; Liang, Zhichao

    2018-03-01

    Laser cutting is suitable for large-scale and high-efficiency production with relatively high cutting speed, while machining of CFRP composite using lasers is challenging with severe thermal damage due to different material properties and sensitivity to heat. In this paper, surface morphology of cutting plain woven carbon fibre-reinforced plastics (CFRP) by fibre laser and the influence of cutting parameters on machined quality were investigated. A full factorial experimental design was employed involving three variable factors, which included laser pulse frequency at three levels together with laser power and cutting speed at two levels. Heat-affected zone (HAZ), kerf depth and kerf angle were quantified to understand the interactions with cutting parameters. Observations of machined surface were analysed relating to various damages using optical microscope and scanning electron microscopy (SEM), which included HAZ, matrix recession, fibre protruding, striations, fibre-end swelling, collapses, cavities and delamination. Based on ANOVA analysis, it was found that both cutting speed and laser power were significant factors for HAZ and kerf depth, while laser power was the only significant factor for kerf angle. Besides, HAZ and the kerf depth showed similar sensitivity to the pulse energy and energy per unit length, which was opposite for kerf angle. This paper presented the feasibility and experimental results of cutting CFRP laminates using fibre laser, which is possibly the efficient and high-quality process to promote the development of CFRPs.

  10. Quantifying Low Energy Proton Damage in Multijunction Solar Cells

    NASA Technical Reports Server (NTRS)

    Messenger, Scott R.; Burke, Edward A.; Walters, Robert J.; Warner, Jeffrey H.; Summers, Geoffrey P.; Lorentzen, Justin R.; Morton, Thomas L.; Taylor, Steven J.

    2007-01-01

    An analysis of the effects of low energy proton irradiation on the electrical performance of triple junction (3J) InGaP2/GaAs/Ge solar cells is presented. The Monte Carlo ion transport code (SRIM) is used to simulate the damage profile induced in a 3J solar cell under the conditions of typical ground testing and that of the space environment. The results are used to present a quantitative analysis of the defect, and hence damage, distribution induced in the cell active region by the different radiation conditions. The modelling results show that, in the space environment, the solar cell will experience a uniform damage distribution through the active region of the cell. Through an application of the displacement damage dose analysis methodology, the implications of this result on mission performance predictions are investigated.

  11. Bulk damage and absorption in fused silica due to high-power laser applications

    NASA Astrophysics Data System (ADS)

    Nürnberg, F.; Kühn, B.; Langner, A.; Altwein, M.; Schötz, G.; Takke, R.; Thomas, S.; Vydra, J.

    2015-11-01

    Laser fusion projects are heading for IR optics with high broadband transmission, high shock and temperature resistance, long laser durability, and best purity. For this application, fused silica is an excellent choice. The energy density threshold on IR laser optics is mainly influenced by the purity and homogeneity of the fused silica. The absorption behavior regarding the hydroxyl content was studied for various synthetic fused silica grades. The main absorption influenced by OH vibrational excitation leads to different IR attenuations for OH-rich and low-OH fused silica. Industrial laser systems aim for the maximum energy extraction possible. Heraeus Quarzglas developed an Yb-doped fused silica fiber to support this growing market. But the performance of laser welding and cutting systems is fundamentally limited by beam quality and stability of focus. Since absorption in the optical components of optical systems has a detrimental effect on the laser focus shift, the beam energy loss and the resulting heating has to be minimized both in the bulk materials and at the coated surfaces. In collaboration with a laser research institute, an optical finisher and end users, photo thermal absorption measurements on coated samples of different fused silica grades were performed to investigate the influence of basic material properties on the absorption level. High purity, synthetic fused silica is as well the material of choice for optical components designed for DUV applications (wavelength range 160 nm - 260 nm). For higher light intensities, e.g. provided by Excimer lasers, UV photons may generate defect centers that effect the optical properties during usage, resulting in an aging of the optical components (UV radiation damage). Powerful Excimer lasers require optical materials that can withstand photon energy close to the band gap and the high intensity of the short pulse length. The UV transmission loss is restricted to the DUV wavelength range below 300 nm and

  12. FreeDam - A webtool for free-electron laser-induced damage in femtosecond X-ray crystallography

    NASA Astrophysics Data System (ADS)

    Jönsson, H. Olof; Östlin, Christofer; Scott, Howard A.; Chapman, Henry N.; Aplin, Steve J.; Tîmneanu, Nicuşor; Caleman, Carl

    2018-03-01

    Over the last decade X-ray free-electron laser (XFEL) sources have been made available to the scientific community. One of the most successful uses of these new machines has been protein crystallography. When samples are exposed to the intense short X-ray pulses provided by the XFELs, the sample quickly becomes highly ionized and the atomic structure is affected. Here we present a webtool dubbed FreeDam based on non-thermal plasma simulations, for estimation of radiation damage in free-electron laser experiments in terms of ionization, temperatures and atomic displacements. The aim is to make this tool easily accessible to scientists who are planning and performing experiments at XFELs.

  13. Comparative study on laser tissue ablation between PV and HPS lasers

    NASA Astrophysics Data System (ADS)

    Kang, Hyun Wook; Jebens, David; Mitchell, Gerald; Koullick, Ed

    2008-02-01

    Laser therapy for obstructive benign prostatic hyperplasia (BPH) has gained broad adoption due to effective tissue removal, immediate hemostasis, and minor complications. The aim of this study is to quantitatively compare ablation characteristics of PV (Photoselective Vaporization) and the newly introduced HPS (High Performance System) 532 nm lasers. Bovine prostatic tissues were ablated in vitro, using a custom-made scanning system. Laser-induced volume produced by two lasers was quantified as a function of applied power, fiber working distance (WD), and treatment speed. Given the same power of 80 W and speed of 4 mm/s, HPS created up to 50 % higher tissue ablation volume than PV did. PV induced a rapid decrease of ablation volume when WD increased from 0.5 mm to 3 mm while HPS yielded almost constant tissue removal up to 3 mm for both 80 W and 120 W. As the treatment speed increased, both lasers reached saturation in tissue ablation volume. Lastly, both PV and HPS lasers exhibited approximately 1 mm thick heat affected zone (HAZ) in this study although HPS created twice deeper ablation channels with a depth of up to 4 mm. Due to a smaller beam size and a higher output power, HPS maximized tissue ablation rate with minimal thermal effects to the adjacent tissue. Furthermore, more collimated beam characteristics provides more spatial flexibility and may even help to decrease the rate of fiber degradation associated with thermal damage from debris reattachment to the tip.

  14. Design of a high pulse repitition frequency carbon dioxide laser for processing high damage threshold materials

    NASA Astrophysics Data System (ADS)

    Chatwin, Christopher R.; McDonald, Donald W.; Scott, Brian F.

    1989-07-01

    The absence of an applications led design philosophy has compromised both the development of laser source technology and its effective implementation into manufacturing technology in particular. For example, CO2 lasers are still incapable of processing classes of refractory and non-ferrous metals. Whilst the scope of this paper is restricted to high power CO2 lasers; the design methodology reported herein is applicable to source technology in general, which when exploited, will effect an expansion of applications. The CO2 laser operational envelope should not only be expanded to incorporate high damage threshold materials but also offer a greater degree of controllability. By a combination of modelling and experimentation the requisite beam characteristics, at the workpiece, were determined then utilised to design the Laser Manufacturing System. The design of sub-system elements was achieved by a combination of experimentation and simulation which benefited from a comprehensive set of software tools. By linking these tools the physical processes in the laser - electron processes in the plasma, the history of photons in the resonator, etc. - can be related, in a detailed model, to the heating mechanisms in the workpiece.

  15. In-vivo optical imaging of hsp70 expression to assess collateral tissue damage associated with infrared laser ablation of skin

    PubMed Central

    Wilmink, Gerald J.; Opalenik, Susan R.; Beckham, Joshua T.; Mackanos, Mark A.; Nanney, Lillian B.; Contag, Christopher H.; Davidson, Jeffrey M.; Jansen, E. Duco

    2013-01-01

    Laser surgical ablation is achieved by selecting laser parameters that remove confined volumes of target tissue and cause minimal collateral damage. Previous studies have measured the effects of wavelength on ablation, but neglected to measure the cellular impact of ablation on cells outside the lethal zone. In this study, we use optical imaging in addition to conventional assessment techniques to evaluate lethal and sublethal collateral damage after ablative surgery with a free-electron laser (FEL). Heat shock protein (HSP) expression is used as a sensitive quantitative marker of sublethal damage in a transgenic mouse strain, with the hsp70 promoter driving luciferase and green fluorescent protein (GFP) expression (hsp70A1-L2G). To examine the wavelength dependence in the mid-IR, laser surgery is conducted on the hsp70A1-L2G mouse using wavelengths targeting water (OH stretch mode, 2.94 μm), protein (amide-II band, 6.45 μm), and both water and protein (amide-I band, 6.10 μm). For all wavelengths tested, the magnitude of hsp70 expression is dose-dependent and maximal 5 to 12 h after surgery. Tissues treated at 6.45 μm have approximately 4× higher hsp70 expression than 6.10 μm. Histology shows that under comparable fluences, tissue injury at the 2.94-μm wavelength was 2× and 3× deeper than 6.45 and 6.10 μm, respectively. The 6.10-μm wavelength generates the least amount of epidermal hyperplasia. Taken together, this data suggests that the 6.10-μm wavelength is a superior wavelength for laser ablation of skin. PMID:19021444

  16. Effect of Proximity of Features on the Damage Threshold During Submicron Additive Manufacturing Via Two-Photon Polymerization

    DOE PAGES

    Saha, Sourabh K.; Divin, Chuck; Cuadra, Jefferson A.; ...

    2017-05-12

    Two-photon polymerization (TPP) is a laser writing process that enables fabrication of millimeter scale three-dimensional (3D) structures with submicron features. In TPP, writing is achieved via nonlinear two-photon absorption that occurs at high laser intensities. Thus, it is essential to carefully select the incident power to prevent laser damage during polymerization. Currently, the feasible range of laser power is identified by writing small test patterns at varying power levels. Here in this paper, we demonstrate that the results of these tests cannot be generalized, because the damage threshold power depends on the proximity of features and reduces by as muchmore » as 47% for overlapping features. We have identified that this reduction occurs primarily due to an increase in the single-photon absorptivity of the resin after curing. We have captured the damage from proximity effects via X-ray 3D computed tomography (CT) images of a non-homogenous part that has varying feature density. Part damage manifests as internal spherical voids that arise due to boiling of the resist. We have empirically quantified this proximity effect by identifying the damage threshold power at different writing speeds and feature overlap spacings. In addition, we present a first-order analytical model that captures the scaling of this proximity effect. Based on this model and the experiments, we have identified that the proximity effect is more significant at high writing speeds; therefore, it adversely affects the scalability of manufacturing. The scaling laws and the empirical data generated here can be used to select the appropriate TPP writing parameters.« less

  17. Effect of Proximity of Features on the Damage Threshold During Submicron Additive Manufacturing Via Two-Photon Polymerization

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Saha, Sourabh K.; Divin, Chuck; Cuadra, Jefferson A.

    Two-photon polymerization (TPP) is a laser writing process that enables fabrication of millimeter scale three-dimensional (3D) structures with submicron features. In TPP, writing is achieved via nonlinear two-photon absorption that occurs at high laser intensities. Thus, it is essential to carefully select the incident power to prevent laser damage during polymerization. Currently, the feasible range of laser power is identified by writing small test patterns at varying power levels. Here in this paper, we demonstrate that the results of these tests cannot be generalized, because the damage threshold power depends on the proximity of features and reduces by as muchmore » as 47% for overlapping features. We have identified that this reduction occurs primarily due to an increase in the single-photon absorptivity of the resin after curing. We have captured the damage from proximity effects via X-ray 3D computed tomography (CT) images of a non-homogenous part that has varying feature density. Part damage manifests as internal spherical voids that arise due to boiling of the resist. We have empirically quantified this proximity effect by identifying the damage threshold power at different writing speeds and feature overlap spacings. In addition, we present a first-order analytical model that captures the scaling of this proximity effect. Based on this model and the experiments, we have identified that the proximity effect is more significant at high writing speeds; therefore, it adversely affects the scalability of manufacturing. The scaling laws and the empirical data generated here can be used to select the appropriate TPP writing parameters.« less

  18. High-damage-threshold antireflection coatings on diamond for CW and pulsed CO2 lasers

    NASA Astrophysics Data System (ADS)

    Komlenok, M. S.; Pivovarov, P. A.; Volodkin, B. O.; Pavelyev, V. S.; Anisimov, V. I.; Butuzov, V. V.; Sorochenko, V. R.; Nefedov, S. M.; Mineev, A. P.; Soifer, V. A.; Konov, V. I.

    2018-03-01

    A multilayer antireflection coating for diamond optics that allows work in the infrared spectral range of 8 -12 µm with minimal optical losses is developed. The optical transmittance of a chemical vapour deposition diamond plate coated with this film on both sides exceeds 94% over the whole specified wavelength range. The coatings deposited on the diamond plate were damage-tested by coherent-wave and pulsed (τ  =  90 ns) CO2 lasers. Results of the tests demonstrated that the coating can withstand prolonged radiation loads with intensity above 3 MW cm-2 in a continuous-mode laser exposure. In the case of a nanosecond pulsed action, destruction of the coating begins at intensities greater than 50 MW cm-2.

  19. Engineered Defects for Investigation of Laser-Induced Damage of Fused Silica at 355nm

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hamza, A V; Siekhaus, W J; Rubenchik, A M

    2001-12-18

    Embedded gold and mechanical deformation in silica were used to investigate initiation of laser-induced damage at 3.55-nm (7.6 ns). The nanoparticle-covered surfaces were coated with between 0 and 500 nm of SiO{sub 2} by e-beam deposition. The threshold for observable damage and initiation site morphology for these ''engineered'' surfaces was determined. The gold nanoparticle coated surfaces with 500nm SiO{sub 2} coating exhibited pinpoint damage threshold of <0.7 J/cm{sup 2} determined by light scattering and Nomarski microscopy. The gold nanoparticle coated surfaces with the 100nm SiO{sub 2} coatings exhibited what nominally appeared to be film exfoliation damage threshold of 19 J/cm{supmore » 2} via light scattering and Nomarski microscopy. With atomic force microscopy pinholes could be detected at fluences greater than 7 J/cm{sup 2} and blisters at fluences greater than 3 J/cm{sup 2} on the 100 nm-coated surfaces. A series of mechanical indents and scratches were made in the fused silica substrates using a nano-indentor. Plastic deformation without cracking led to damage thresholds of -25 J/cm{sup 2}, whereas indents and scratches with cracking led to damage thresholds of only {approx}5 J/cm{sup 2}. Particularly illuminating was the deterministic damage of scratches at the deepest end of the scratch, as if the scratch acted as a waveguide.« less

  20. Laser-induced damage threshold measurements of optical dielectric coatings at lambda = 1.06 micron

    NASA Astrophysics Data System (ADS)

    Milev, I. Ia.; Dimov, S. S.; Terziev, D. V.; Iordanova, J. I.; Todorova, L. B.; Gelkova, A. B.

    1991-10-01

    The laser-induced damage thresholds for lambda = 1.06 micron of commercially available dielectric optical coatings, both antireflective and high reflectance, have been determined. The dependence of the optical coatings stability on design and selection of materials has been investigated. An improvement of the coatings durability by using nonquarterwave layers in addition to the basic design of the mirrors has been obtained. The choice of the coating materials is also discussed.

  1. Propagation Effects in the Assessment of Laser Damage Thresholds to the Eye and Skin

    DTIC Science & Technology

    2007-01-01

    Conference on Optical Interactions with Tissue and Cells [18th] Held in San Jose, California on January 22-24, 2007 To order the complete compilation report...evaluation of the role of propagation with regard to laser damage to tissues. Regions of the optical spectrum, where linear and non-linear propagation...photo-chemical toxicity. Exposure limits commonly address skin and eye hazards through separate definitions. Differing optical absorption and scattering

  2. Wavelength dependence of laser-induced retinal injury

    NASA Astrophysics Data System (ADS)

    Lund, David J.; Edsall, Peter; Stuck, Bruce E.

    2005-04-01

    The threshold for laser-induced retinal damage is dependent primarily upon the laser wavelength and the exposure duration. The study of the wavelength dependence of the retinal damage threshold has been greatly enhanced by the availability of tunable lasers. The Optical Parametric Oscillator (OPO), capable of providing useful pulse energy throughout a tuning range from 400 nm to 2200 nm, made it possible to determine the wavelength dependence of laser-induced retinal damage thresholds for q-switched pulses throughout the visible and NIR spectrum. Studies using the a tunable TI:Saph laser and several fixed-wavelength lasers yielded threshold values for 0.1 s exposures from 440 nm to 1060 nm. Laser-induced retinal damage for these exposure durations results from thermal conversion of the incident laser irradiation and an action spectrum for thermal retinal damage was developed based on the wavelength dependent transmission and absorption of ocular tissue and chromatic aberration of the eye optics. Long (1-1000s) duration exposures to visible laser demonstrated the existence of non-thermal laser-induced retinal damage mechanisms having a different action spectrum. This paper will present the available data for the wavelength dependence of laser-induced thermal retinal damage and compare this data to the maximum permissible exposure levels (MPEs) provided by the current guidelines for the safe use of lasers.

  3. Influence of resonator length on catastrophic optical damage in high-power AlGaInP broad-area lasers

    NASA Astrophysics Data System (ADS)

    Bou Sanayeh, Marwan

    2017-05-01

    The increasing importance of extracting high optical power out of semiconductor lasers motivated several studies in catastrophic optical damage (COD) level improvement. In this study, the influence of the resonator length in high-power broad-area (BA) AlGaInP lasers on COD is presented. For the analyses, several 638 nm AlGaInP 60 μm BA lasers from the same wafer were used. Resonator lengths of 900, 1200, 1500, and 1800 μm were compared. In order to independently examine the effect of the resonator length on the maximum power reached by the lasers before COD (PCOD), the lasers used are uncoated and unmounted, and PCOD under pulsed mode was determined. It was found that higher output powers and eventually higher PCOD can be achieved using longer resonators; however, it was also found that this is mainly useful when working at high output powers far away from the laser threshold, since the threshold current and slope efficiency worsen when the resonator length increases.

  4. Laser induced photoreceptor damage and recovery in the high numerical aperture eye of the garter snake.

    PubMed

    Zwick, H; Edsall, P; Stuck, B E; Wood, E; Elliott, R; Cheramie, R; Hacker, H

    2008-02-01

    The garter snake provides a unique model for in-vivo imaging of photoreceptor damage induced by laser retinal exposure. Laser thermal/mechanical retinal injury induced alterations in photoreceptor structure and leukocyte cellular behavior. Photoreceptors turned white, lost mode structure, and swelled; leukocyte activity was observed in the vicinity of photoreceptor cells. Non-thermal alterations were identified with a bio-tag for oxidative stress. Mechanisms of photoreceptor recovery and replacement were observed and evaluated for active cytoskeletal systems by using an anti-actin tag that could detect the presence of active cytoskeletal systems resident in photoreceptors as well as other retinal systems.

  5. Land Use in LCA: Including Regionally Altered Precipitation to Quantify Ecosystem Damage.

    PubMed

    Lathuillière, Michael J; Bulle, Cécile; Johnson, Mark S

    2016-11-01

    The incorporation of soil moisture regenerated by precipitation, or green water, into life cycle assessment has been of growing interest given the global importance of this resource for terrestrial ecosystems and food production. This paper proposes a new impact assessment model to relate land and water use in seasonally dry, semiarid, and arid regions where precipitation and evapotranspiration are closely coupled. We introduce the Precipitation Reduction Potential midpoint impact representing the change in downwind precipitation as a result of a land transformation and occupation activity. Then, our end-point impact model quantifies terrestrial ecosystem damage as a function of precipitation loss using a relationship between woody plant species richness, water and energy regimes. We then apply the midpoint and end-point models to the production of soybean in Southeastern Amazonia which has resulted from the expansion of cropland into tropical forest, with noted effects on local precipitation. Our proposed cause-effect chain represents a complementary approach to previous contributions which have focused on water consumption impacts and/or have represented evapotranspiration as a loss to the water cycle.

  6. Correlation between He-Ne scatter and 2.7-microm pulsed laser damage at coating defects.

    PubMed

    Porteus, J O; Spiker, C J; Franck, J B

    1986-11-01

    A reported correlation between defect-initiated pulsed laser damage and local predamage scatter in multilayer infrared mirror coatings has been analyzed in detail. Examination of a much larger data base confirms the previous result on dielectric-enhanced reflectors with polished substrates over a wide range of energy densities above the damage onset. Scatter signals from individual undamaged defects were detected using a He-Ne scatter probe with a focal spot that nearly coincides with the 150-microm-diam (D1/e(2)) focal spot of the damage-probe beam. Subsequent damage frequency measurements (1-on-1) were made near normal or at 45 degrees incidence with 100-ns pulses at 2.7-microm wavelength. The correlation is characterized by an increase in damage frequency with increasing predamage scatter signal and by equivalence of the defect densities indicated by the two probes. Characteristics of the correlation are compared with a simple model based on focal spot intensity profiles. Conditions that limit correlation are discussed, including variable scatter from defects and background scatter from diamond-turned substrates. Results have implication for nondestructive defect detection and coating quality control.

  7. Optical coatings for laser fusion applications

    NASA Astrophysics Data System (ADS)

    Lowdermilk, W. H.; Milam, D.; Rainer, F.

    1980-04-01

    Lasers for fusion experiments use thin-film dielectric coatings for reflecting antireflecting and polarizing surface elements. Coatings are most important to the Nd:glass laser application. The most important requirements of these coatings are accuracy of the average value of reflectance and transmission, uniformity of amplitude and phase front of the reflected or transmitted light, and laser damage threshold. Damage resistance strongly affects the laser's design and performance. The success of advanced lasers for future experiments and for reactor applications requires significant developments in damage resistant coatings for ultraviolet laser radiation.

  8. Comparison of solar and laser macula retinal injury using scanning laser ophthalmoscopy spectral imaging

    NASA Astrophysics Data System (ADS)

    Zwick, Harry; Gagliano, Donald A.; Stuck, Bruce E.; Lund, David J.

    1994-07-01

    Both solar and laser sources may induce punctate foveal retinal damage. Unprotected viewing of the sun or bright blue sky represent potential solar radiation causes of photic maculopathy that may induce punctate foveal damage. Laser induced macular retinal damage is another more recent kind of photic maculopathy. Most documented cases of laser photic maculopathy have involved acute laser exposure generally from Q-switched visible or nonvisible near IR laser systems. In our comparison of these types of photic maculopathies, we have employed conventional as well as spectral and confocal scanning laser ophthalomoscopy to evaluate the depth of the photic maculopathy. Functionally, we have observed a tritan color vision loss present in nearly all photic maculopathies.

  9. Influence of dielectric protective layer on laser damage resistance of gold coated gratings

    NASA Astrophysics Data System (ADS)

    Wu, Kepeng; Ma, Ping; Pu, Yunti; Xia, Zhilin

    2016-03-01

    Aiming at the problem that the damage threshold of gold coated grating is relatively low, a dielectric film is considered on the gold coated gratings as a protective layer. The thickness range of the protective layer is determined under the prerequisite that the diffraction efficiency of the gold coated grating is reduced to an acceptable degree. In this paper, the electromagnetic field, the temperature field and the stress field distribution in the grating are calculated when the silica and hafnium oxide are used as protective layers, under the preconditions of the electromagnetic field distribution of the gratings known. The results show that the addition of the protective layer changes the distribution of the electromagnetic field, temperature field and stress field in the grating, and the protective layer with an appropriate thickness can improve the laser damage resistance of the grating.

  10. Laser-shock damage of iron-based materials

    NASA Astrophysics Data System (ADS)

    Chu, Jinn P.; Banas, Grzegorz; Lawrence, Frederick V.; Rigsbee, James M.; Elsayed-Ali, Hani E.

    1993-05-01

    The effects of laser shock processing on the microstructure and mechanical properties of the manganese (1 percent C and 14 percent Mn) steels have been low carbon (0.04 wt. percent C) and Hadfield studied. Laser shock processing was performed with a 1.054 micrometers wavelength Nd-phosphate laser operating in a pulse mode (600 ps pulse length and up to 200 J energy) with power densities above 10 to the 11th power W/cm2. Shock waves were generated by volume expansion of the plasma formed when the material was laser irradiated. Maximum shock wave intensities were obtained using an energy-absorbing black paint coating without a plasma-confining overlay. Maximum modification of compressive residual stresses were achieved when laser shock processing induced deformation occurred without melting. Mechanical properties were improved through modifying the microstructure by laser shock processing. High density arrays of dislocations (greater than 10 to the 11th power/cm2) were generated in low carbon steel by high strain-rate deformation of laser shock processing, resulting in surface hardness increases of 30 to 80 percent. In austenitic Hadfield steel, laser shock processing caused extensive formation of Epsilon-hcp martensite (35 vol. percent), producing increases of 50 to 130 percent in surface hardness. The laser shock processing strengthening effect in Hadfield steel was attributed to the combined effects of the partial dislocation/stacking fault arrays and the grain refinement due to presence of the Epsilon-hcp martensite.

  11. Experimental and simulated ultrasonic characterization of complex damage in fused silica.

    PubMed

    Martin, L Peter; Chambers, David H; Thomas, Graham H

    2002-02-01

    The growth of a laser-induced, surface damage site in a fused silica window was monitored by the ultrasonic pulse-echo technique. The laser damage was grown using 12-ns pulses of 1.053-microm wavelength light at a fluence of approximately 27 J/cm2. The ultrasonic data were acquired after each pulse of the laser beam for 19 pulses. In addition, optical images of the surface and subsurface damage shape were recorded after each pulse of the laser. The ultrasonic signal amplitude exhibited variations with the damage size, which were attributed to the subsurface morphology of the damage site. A mechanism for the observed ultrasonic data based on the interaction of the ultrasound with cracks radiating from the damage site was tested using two-dimensional numerical simulations. The simulated results exhibit qualitatively similar characteristics to the experimental data and demonstrate the usefulness of numerical simulation as an aid for ultrasonic signal interpretation. The observed sensitivity to subsurface morphology makes the ultrasonic methodology a promising tool for monitoring laser damage in large aperture laser optics used in fusion energy research.

  12. An Assessment of Molecular Dynamic Force Fields for Silica for Use in Simulating Laser Damage Mitigation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Soules, T F; Gilmer, G H; Matthews, M J

    2010-10-21

    We compare force fields (FF's) that have been used in molecular dynamic (MD) simulations of silica in order to assess their applicability for use in simulating IR-laser damage mitigation. Although pairwise FF?s obtained by fitting quantum mechanical calculations such as the BKS and CHIK potentials have been shown to reproduce many of the properties of silica including the stability of silica polymorphs and the densification of the liquid, we show that melting temperatures and fictive temperatures are much too high. Softer empirical force fields give liquid and glass properties at experimental temperatures but may not predict all properties important tomore » laser mitigation experiments.« less

  13. Defect evolution during catastrophic optical damage in 450-nm emitting InGaN/GaN diode lasers

    NASA Astrophysics Data System (ADS)

    Tomm, Jens W.; Kernke, Robert; Löffler, Andreas; Stojetz, Bernhard; Lell, Alfred; König, Harald

    2018-02-01

    The catastrophic optical damage (COD) of 450-nm emitting InGaN/GaN diode lasers is investigated with special attention to the kinetics of the process. For this purpose, the COD is triggered artificially by applying individual current pulses. This makes it possible to achieve a sub-µs time resolution for processes monitored by cameras. COD appears as a "hot" process that involves decomposition of quantum well and waveguide materials. We observe the ejection of hot material from the front facets of the laser. This can be seen in two different wavelength ranges, visible/near infrared and mid infrared. The main contributions identified are both thermal radiation and 450-nm laser light scattered by the emitted material. Defect growth during COD is energized by the optical mode. Therefore, the defect pattern resembles its shape. Ultimately, the loss of material leads to the formation of an empty channel along the laser axis. COD in GaAs and GaN-based devices follows similar general scenarios. After ignition of the process, the defect propagation during the process is fed by laser energy. We observe defect propagation velocities of up to 30 m/s for GaAs-based devices and 110 m/s for GaN-based devices. The damage patterns of GaN and GaAs-based devices are completely different. For GaN-based devices, the front facets show holes. Behind them in the interior, we find an empty channel at the position of the optical mode surrounded by intact material. In contrast, earlier studies on GaAs-based devices that were degraded under almost identical conditions resulted in molten, phase separated and both recrystallized and amorphous materials with well-defined melting fronts.

  14. Studies on transmitted beam modulation effect from laser induced damage on fused silica optics.

    PubMed

    Zheng, Yi; Ma, Ping; Li, Haibo; Liu, Zhichao; Chen, Songlin

    2013-07-15

    UV laser induced damage (LID) on exit surface of fused silica could cause modulation effect to transmitted beam and further influence downstream propagation properties. This paper presents our experimental and analytical studies on this topic. In experiment, a series of measurement instruments are applied, including beam profiler, interferometer, microscope, and optical coherent tomography (OCT). Creating and characterizing of LID on fused silica sample have been implemented. Morphological features are studied based on their particular modulation effects on transmitted beam. In theoretical investigation, analytical modeling and numerical simulation are performed. Modulation effects from amplitude, phase, and size factors are analyzed respectively. Furthermore, we have novelly designed a simplified polygon model to simulate actual damage site with multiform modulation features, and the simulation results demonstrate that the modeling is usable and representative.

  15. Determination of SBS induced damage limits in large fused silica optics for intense, time varying laser pulses

    NASA Astrophysics Data System (ADS)

    Kyrazis, D. T.; Weiland, T. L.

    1990-10-01

    The propagation of intense 3rd harmonic light (0.351 micron) through large optical components of the Nova laser results in fracture damage of the center of the component. This damage is caused by an intense acoustical wave brought to focus in the center by reflecting off the circular edge of the optic. The source of this wave is light generated by transverse stimulated Brillouin scattering (SBS). By taking into account the transient gain characteristics of the SBS, the pulse energy can be correctly predicted that would cause damage for any time variation in intensity in the pump beam, and predict the relative intensity of the Brillouin light. The model is based on the transient behavior of a first order linear system.

  16. Very high laser-damage threshold of polymer-derived Si(B)CN-carbon nanotube composite coatings.

    PubMed

    Bhandavat, R; Feldman, A; Cromer, C; Lehman, J; Singh, G

    2013-04-10

    We study the laser irradiance behavior and resulting structural evolution of polymer-derived silicon-boron-carbonitride (Si(B)CN) functionalized multiwall carbon nanotube (MWCNT) composite spray coatings on copper substrate. We report a damage threshold value of 15 kWcm(-2) and an optical absorbance of 0.97 after irradiation. This is an order of magnitude improvement over MWCNT (1.4 kWcm(-2), 0.76), SWCNT (0.8 kWcm(-2), 0.65) and carbon paint (0.1 kWcm(-2), 0.87) coatings previously tested at 10.6 μm (2.5 kW CO2 laser) exposure. Electron microscopy, Raman spectroscopy, and X-ray photoelectron spectroscopy suggests partial oxidation of Si(B)CN forming a stable protective SiO2 phase upon irradiation.

  17. Quantifying uncertainty in soot volume fraction estimates using Bayesian inference of auto-correlated laser-induced incandescence measurements

    NASA Astrophysics Data System (ADS)

    Hadwin, Paul J.; Sipkens, T. A.; Thomson, K. A.; Liu, F.; Daun, K. J.

    2016-01-01

    Auto-correlated laser-induced incandescence (AC-LII) infers the soot volume fraction (SVF) of soot particles by comparing the spectral incandescence from laser-energized particles to the pyrometrically inferred peak soot temperature. This calculation requires detailed knowledge of model parameters such as the absorption function of soot, which may vary with combustion chemistry, soot age, and the internal structure of the soot. This work presents a Bayesian methodology to quantify such uncertainties. This technique treats the additional "nuisance" model parameters, including the soot absorption function, as stochastic variables and incorporates the current state of knowledge of these parameters into the inference process through maximum entropy priors. While standard AC-LII analysis provides a point estimate of the SVF, Bayesian techniques infer the posterior probability density, which will allow scientists and engineers to better assess the reliability of AC-LII inferred SVFs in the context of environmental regulations and competing diagnostics.

  18. Application of CO laser for laser balloon angioplasty

    NASA Astrophysics Data System (ADS)

    Miyamoto, Akira; Sakurada, Masami; Mizuno, Kyoichi; Kurita, Akira; Nakamura, Haruo; Suda, Akira; Arai, Tsunenori; Kikuchi, Makoto

    1990-07-01

    CO laser may be efficient for thermal fusion of intima of arterial wall without adventitial tissue damage because of high tissue absorption. To investigate the efficacy of CO laser as a laser bam for laser balloon angioplasty (LBA). CO laser was irradiated to aortic tissue through 3Oim polyethylene membrane and tissue temperature was measured by a thermistor. At 2Owatt/cm2 200joules/cm2 continuous laser exposure (CE), tissue temperature was above 100°C within a depth of 1mm and rapidly decreased to 60 °C or below between 2 and 3mm in depth. Moreover, adventitial temperature could be decreased by changing duty ratio (exposure duration/interval) of intermittent laser exposure (IE) despite of the same laser energy. Light microscopy showed high degree of medial coagulation necrosis in CE, however thermal coagulation was observed only at the surface of intima of aortic tissue in IE at duty ratio 1 / 2. These findings suggested CO laser could coagulate intimal layer with less deep thermal damage compared to Nd- YAG laser and that IE was better for superficial welding than CE at the same energy. We concluded that CO laser might be more efficient as a laser beam for LBA than Nd-YAG laser.

  19. Terrestrial laser scanning to quantify above-ground biomass of structurally complex coastal wetland vegetation

    NASA Astrophysics Data System (ADS)

    Owers, Christopher J.; Rogers, Kerrylee; Woodroffe, Colin D.

    2018-05-01

    Above-ground biomass represents a small yet significant contributor to carbon storage in coastal wetlands. Despite this, above-ground biomass is often poorly quantified, particularly in areas where vegetation structure is complex. Traditional methods for providing accurate estimates involve harvesting vegetation to develop mangrove allometric equations and quantify saltmarsh biomass in quadrats. However broad scale application of these methods may not capture structural variability in vegetation resulting in a loss of detail and estimates with considerable uncertainty. Terrestrial laser scanning (TLS) collects high resolution three-dimensional point clouds capable of providing detailed structural morphology of vegetation. This study demonstrates that TLS is a suitable non-destructive method for estimating biomass of structurally complex coastal wetland vegetation. We compare volumetric models, 3-D surface reconstruction and rasterised volume, and point cloud elevation histogram modelling techniques to estimate biomass. Our results show that current volumetric modelling approaches for estimating TLS-derived biomass are comparable to traditional mangrove allometrics and saltmarsh harvesting. However, volumetric modelling approaches oversimplify vegetation structure by under-utilising the large amount of structural information provided by the point cloud. The point cloud elevation histogram model presented in this study, as an alternative to volumetric modelling, utilises all of the information within the point cloud, as opposed to sub-sampling based on specific criteria. This method is simple but highly effective for both mangrove (r2 = 0.95) and saltmarsh (r2 > 0.92) vegetation. Our results provide evidence that application of TLS in coastal wetlands is an effective non-destructive method to accurately quantify biomass for structurally complex vegetation.

  20. Method and apparatus for reducing diffraction-induced damage in high power laser amplifier systems

    DOEpatents

    Campillo, Anthony J.; Newnam, Brian E.; Shapiro, Stanley L.; Terrell, Jr., N. James

    1976-01-01

    Self-focusing damage caused by diffraction in laser amplifier systems may be minimized by appropriately tailoring the input optical beam profile by passing the beam through an aperture having a uniform high optical transmission within a particular radius r.sub.o and a transmission which drops gradually to a low value at greater radii. Apertures having the desired transmission characteristics may readily be manufactured by exposing high resolution photographic films and plates to a diffuse, disk-shaped light source and mask arrangement.

  1. Laser speckle tracking for monitoring and analysis of retinal photocoagulation

    NASA Astrophysics Data System (ADS)

    Seifert, Eric; Bliedtner, Katharina; Brinkmann, Ralf

    2014-02-01

    Laser coagulation of the retina is an established treatment for several retinal diseases. The absorbed laser energy and thus the induced thermal damage varies with the transmittance and scattering properties of the anterior eye media and with the pigmentation of the fundus. The temperature plays the most important role in the coagulation process. An established approach to measure a mean retinal temperature rise is optoacoustics, however it provides limited information on the coagulation. Phase sensitive OCT potentially offers a three dimensional temporally resolved temperature distribution but is very sensitive to slightest movements which are clinically hard to avoid. We develop an optical technique able to monitor and quantify thermally and coagulation induced tissue movements (expansions and contractions) and changes in the tissue structure by dynamic laser speckle analysis (LSA) offering a 2D map of the affected area. A frequency doubled Nd:YAG laser (532nm) is used for photocoagulation. Enucleated porcine eyes are used as targets. The spot is 100μm. A Helium Neon laser (HeNe) is used for illumination. The backscattered light of a HeNe is captured with a camera and the speckle pattern is analyzed. A Q-switched Nd:YLF laser is used for simultaneous temperature measurements with the optoacoustic approach. Radial tissue movements in the micrometer regime have been observed. The signals evaluation by optical flow algorithms and generalized differences tuned out to be able to distinguish between regions with and without immediate cell damage. Both approaches have shown a sensitivity of 93% and a specificity above 99% at their optimal threshold.

  2. Fundamental studies in the molecular basis of laser-induced retinal damage. Annual report, September 1981-August 1982

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lewis

    1982-09-01

    This research led to new insights in the fundamental mechanisms involved in laser induced retinal damage and some of the fundamental work on these mechanisms lead to new and exciting avenues in the development of rapidly adjustable molecular light filters with important new possibilities for pulsed-laser eye protection. This report summarizes the significant progress of the past year: (1) Development and Fundamental Mechanism of a Rapidly Adjustable Molecular Filter for Pulsed Laser Eye Protection - this research direction resulted from our investigations on cones of the red-eared swamp turtle, Pseudemys scripta elegans. (2) The Optical Density of Turtle Oil Dropletmore » Solutions - it is important both from a practical and fundamental point of view to determine the optical density of turtle oil-droplet suspensions. In view of the high optical densities in this system, tunable-laser resonance Raman spectroscopy, which is the only technique that has been able to provide high-resolution data, is the only technique that is potentially able to obtain the information. (3) Laser-Induced Molecular Alterations in Turtle Retina. (4) Light Driven Enzymatic Reactions in Photoreceptors. (5) Molecular Cytology of Rod Outer Segments.« less

  3. Ultraviolet Laser Damage Dependence on Contamination Concentration in Fused Silica Optics during Reactive Ion Etching Process

    PubMed Central

    Sun, Laixi; Shao, Ting; Shi, Zhaohua; Huang, Jin; Ye, Xin; Jiang, Xiaodong; Wu, Weidong; Yang, Liming; Zheng, Wanguo

    2018-01-01

    The reactive ion etching (RIE) process of fused silica is often accompanied by surface contamination, which seriously degrades the ultraviolet laser damage performance of the optics. In this study, we find that the contamination behavior on the fused silica surface is very sensitive to the RIE process which can be significantly optimized by changing the plasma generating conditions such as discharge mode, etchant gas and electrode material. Additionally, an optimized RIE process is proposed to thoroughly remove polishing-introduced contamination and efficiently prevent the introduction of other contamination during the etching process. The research demonstrates the feasibility of improving the damage performance of fused silica optics by using the RIE technique. PMID:29642571

  4. Effects of copper vapor laser (CVL) on mice skin: histologic evaluation of damage and tissue stimulation

    NASA Astrophysics Data System (ADS)

    Nunes, Syllene; Moreno, E.; Oliveira, H.; Osaka, J.; Salvador, G.; Michalany, N.; Tolosa, E.

    2002-10-01

    This study was to evaluate the effects of the CVL with low energy and short pulse widths. 18 female mice, C57BL/6 (9-11 weeks old) were distributed into four groups. The control group (CG) wasn't exposed to laser beam . Group L1 had 2 laser expositions with 24 hours gap between them (0.5W). Group L2 had 3 expositions (0.5W and 0.25W) and group L3 had 4 expositions (0.25 W). It was used a CVL prototype (5lOnm, 13 Khz, pulse width of 20 ms and spot size of 0.8cm). 7 days after last laser pulse no groups presented actinic keratosis, tumors or collagen changes. CVL had effective action on pilosebaceous units. High energy with few short pulses induced hair follicles proliferation while low energy with many repetitive short pulses showed increased and specific tissue damage besides hair plugging.

  5. Influence of radiation damage on ruby as a pressure gauge

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schuster, B.; GSI Helmholtzzentrum fuer Schwerionenforschung, Planckstr. 1, 64291 Darmstadt; Weikusat, C.

    2010-11-01

    This study tackles the question if ruby crystals, irradiated with energetic heavy ions, can still be used as reliable pressure sensors. The problem is linked to novel irradiation experiments, exposing pressurized samples to swift heavy-ion beams. In order to test and quantify a possible influence of radiation damage on the laser-induced fluorescence lines of ruby (Al{sub 2}O{sub 3}:Cr{sup 3+}), small crystals were exposed to different heavy ions (Xe, Au, and U) with kinetic energies of several giga-electron volt at ambient as well as high-pressure conditions. With increasing fluence (ions/cm{sup 2}), the R{sub 1} and R{sub 2} lines shift both tomore » lower wavelengths which leads to an underestimation of the pressure. An empirical correction term {epsilon} is proposed to include the irradiation damage effect into the commonly employed ruby calibration scale.« less

  6. DNA damage in wounded, hypoxic and acidotic human skin fibroblast cell cultures after low laser irradiation

    NASA Astrophysics Data System (ADS)

    Hawkins Evans, D.; Mbene, A.; Zungu, I.; Houreld, N.; Abrahamse, H.

    2009-02-01

    Phototherapy has become more popular and widely used in the treatment of a variety of medical conditions. To ensure sound results as evidence of its effectiveness, well designed experiments must be conducted when determining the effect of phototherapy. Cell culture models such as hypoxic, acidotic and wounded cell cultures simulating different disease conditions including ischemic heart disease, diabetes and wound healing were used to determine the effect of laser irradiation on the genetic integrity of the cell. Even though phototherapy has been found to be beneficial in a wide spectrum of conditions, it has been shown to induce DNA damage. However, this damage appears to be repairable. The risk lies in the fact that phototherapy may help the medical condition initially but damage DNA at the same time leaving undetected damage that may result in late onset, more severe, induced medical conditions including cancer. Human skin fibroblasts were cultured and used to induce a wound (by the central scratch model), hypoxic (by incubation in an anaerobic jar, 95% N2 and 5% O2) and acidotic (reducing the pH of the media to 6.7) conditions. Different models were irradiated using a Helium-Neon (632.8 nm) laser with a power density of 2.07 mW/cm2 and a fluence of 5 J/cm2 or 16 J/cm2. The effect of the irradiation was determined using the Comet assay 1 and 24 h after irradiation. In addition, the Comet assay was performed with the addition of formamidopyrimidine glycosylase (FPG) obviating strand brakes in oxidized bases at a high fluence of 16 J/cm2. A significant increase in DNA damage was seen in all three injured models at both 1 and 24 h post-irradiation when compared to the normal un-injured cells. However, when compared to non-irradiated controls the acidotic model showed a significant decrease in DNA damage 24 h after irradiation indicating the possible induction of cellular DNA repair mechanisms. When wounded cells were irradiated with higher fluences of 16 J/cm2

  7. Permanent laser conditioning of thin film optical materials

    DOEpatents

    Wolfe, C. Robert; Kozlowski, Mark R.; Campbell, John H.; Staggs, Michael; Rainer, Frank

    1995-01-01

    The invention comprises a method for producing optical thin films with a high laser damage threshold and the resulting thin films. The laser damage threshold of the thin films is permanently increased by irradiating the thin films with a fluence below an unconditioned laser damage threshold.

  8. Precision Laser Annealing of Focal Plane Arrays

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bender, Daniel A.; DeRose, Christopher; Starbuck, Andrew Lea

    2015-09-01

    We present results from laser annealing experiments in Si using a passively Q-switched Nd:YAG microlaser. Exposure with laser at fluence values above the damage threshold of commercially available photodiodes results in electrical damage (as measured by an increase in photodiode dark current). We show that increasing the laser fluence to values in excess of the damage threshold can result in annealing of a damage site and a reduction in detector dark current by as much as 100x in some cases. A still further increase in fluence results in irreparable damage. Thus we demonstrate the presence of a laser annealing windowmore » over which performance of damaged detectors can be at least partially reconstituted. Moreover dark current reduction is observed over the entire operating range of the diode indicating that device performance has been improved for all values of reverse bias voltage. Additionally, we will present results of laser annealing in Si waveguides. By exposing a small (<10 um) length of a Si waveguide to an annealing laser pulse, the longitudinal phase of light acquired in propagating through the waveguide can be modified with high precision, <15 milliradian per laser pulse. Phase tuning by 180 degrees is exhibited with multiple exposures to one arm of a Mach-Zehnder interferometer at fluence values below the morphological damage threshold of an etched Si waveguide. No reduction in optical transmission at 1550 nm was found after 220 annealing laser shots. Modeling results for laser annealing in Si are also presented.« less

  9. Nano-indentation and laser-induced damage testing in optical multilayer-dielectric gratings [Nanomechanics and laser-induced damage in optical multilayer dielectric gratings

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mehrotra, K.; Corning Research & Development Corp., Coming, NY; Taylor, B. N.

    Here, we demonstrate how a nanomechanical test can be used to generate metrics to complement laser-induced–damage testing (LIDT) measurements and show that differences in optical performance of the gratings (arising from changes in cleaning process and/or fabrication methods) can be related to their mechanical reliability. Data are presented on LIDT measurements in diffractive gratings of silica deposited on optical multilayers. The nano-indentation response of the diffraction gratings is measured in a new mode that allows for the extraction of a measurable metric characterizing the brittleness of the gratings, as well as their ductility. We show that lower LIDT’s are positivelymore » correlated with an increased grating brittleness, and therefore identify a nanomechanical approach to describe LIDT’s. We present extensive numerical simulations of nano-indentation tests and identify different deformation modes including stretching, shear concentration, and bending as precursors to mechanical failure in the nano-indentation test. The effects of geometrical inhomogeneities on enhanced stress generation in these gratings are specifically examined and addressed.« less

  10. Nano-indentation and laser-induced damage testing in optical multilayer-dielectric gratings [Nanomechanics and laser-induced damage in optical multilayer dielectric gratings

    DOE PAGES

    Mehrotra, K.; Corning Research & Development Corp., Coming, NY; Taylor, B. N.; ...

    2017-03-16

    Here, we demonstrate how a nanomechanical test can be used to generate metrics to complement laser-induced–damage testing (LIDT) measurements and show that differences in optical performance of the gratings (arising from changes in cleaning process and/or fabrication methods) can be related to their mechanical reliability. Data are presented on LIDT measurements in diffractive gratings of silica deposited on optical multilayers. The nano-indentation response of the diffraction gratings is measured in a new mode that allows for the extraction of a measurable metric characterizing the brittleness of the gratings, as well as their ductility. We show that lower LIDT’s are positivelymore » correlated with an increased grating brittleness, and therefore identify a nanomechanical approach to describe LIDT’s. We present extensive numerical simulations of nano-indentation tests and identify different deformation modes including stretching, shear concentration, and bending as precursors to mechanical failure in the nano-indentation test. The effects of geometrical inhomogeneities on enhanced stress generation in these gratings are specifically examined and addressed.« less

  11. Effect of Li and NH4 doping on the crystal perfection, second harmonic generation efficiency and laser damage threshold of potassium pentaborate crystals

    NASA Astrophysics Data System (ADS)

    Vigneshwaran, A. N.; Kalainathan, S.; Raja, C. Ramachandra

    2018-03-01

    Potassium pentaborate (KB5) is an excellent nonlinear optical material especially in the UV region. In this work, Li and NH4 doped KB5 crystals were grown using slow evaporation solution growth method. The incorporation of dopant has been confirmed and analysed by Energy dispersive X-ray analysis (EDAX), Inductively coupled plasma (ICP) analysis and Raman spectroscopy. The crystalline perfection of pure and doped KB5 crystals was studied by High resolution X-ray diffraction (HRXRD) analysis. Structural grain boundaries were observed in doped crystals. Second harmonic generation was confirmed for pure and doped crystals and output values revealed the enhancement of SHG efficiency in doped crystals. Resistance against laser damage was carried out using 1064 nm Nd-YAG laser of pulse width 10 ns. The laser damage threshold value is increased in Li doped crystal and decreased in NH4 doped crystal when compared to pure KB5 crystal.

  12. Permanent laser conditioning of thin film optical materials

    DOEpatents

    Wolfe, C.R.; Kozlowski, M.R.; Campbell, J.H.; Staggs, M.; Rainer, F.

    1995-12-05

    The invention comprises a method for producing optical thin films with a high laser damage threshold and the resulting thin films. The laser damage threshold of the thin films is permanently increased by irradiating the thin films with a fluence below an unconditioned laser damage threshold. 9 figs.

  13. Damage mechanisms avoided or managed for NIF large optics

    DOE PAGES

    Manes, K. R.; Spaeth, M. L.; Adams, J. J.; ...

    2016-02-09

    After every other failure mode has been considered, in the end, the high-performance limit of all lasers is set by optical damage. The demands of inertial confinement fusion (ICF) pushed lasers designed as ICF drivers into this limit from their very earliest days. The first ICF lasers were small, and their pulses were short. Their goal was to provide as much power to the target as possible. Typically, they faced damage due to high intensity on their optics. As requests for higher laser energy, longer pulse lengths, and better symmetry appeared, new kinds of damage also emerged, some of themmore » anticipated and others unexpected. This paper will discuss the various types of damage to large optics that had to be considered, avoided to the extent possible, or otherwise managed as the National Ignition Facility (NIF) laser was designed, fabricated, and brought into operation. Furthermore, it has been possible for NIF to meet its requirements because of the experience gained in previous ICF systems and because NIF designers have continued to be able to avoid or manage new damage situations as they have appeared.« less

  14. Intraocular laser surgical probe for membrane disruption by laser-induced breakdown.

    PubMed

    Hammer, D X; Noojin, G D; Thomas, R J; Clary, C E; Rockwell, B A; Toth, C A; Roach, W P

    1997-03-01

    A fiber probe has been designed as a surgical aid to cut intraocular membranes with laser-induced breakdown as the mechanism. The design of the intraocular laser surgical probe is discussed. A preliminary retinal damage distance has been calculated with breakdown threshold, spot size, and shielding measurements. Collateral mechanical-damage effects caused by shock wave and cavitation are discussed.

  15. Comparison of Epidermal/Dermal Damage Between the Long-Pulsed 1064 nm Nd:YAG and 755 nm Alexandrite Lasers Under Relatively High Fluence Conditions: Quantitative and Histological Assessments

    PubMed Central

    Lee, Ju Hwan; Park, So Ra; Jo, Jeong Ho; Park, Sung Yun; Seo, Young Kwon

    2014-01-01

    Abstract Objective: The purpose of this study was to compare degrees of epidermal/dermal tissue damage quantitatively and histologically after laser irradiation, to find ideal treatment conditions with relatively high fluence for skin rejuvenation. Background data: A number of recent studies have evaluated the clinical efficacy and safety of therapeutic lasers under relatively low fluence conditions. Methods: We transmitted the long-pulsed 1064 nm Nd:YAG and 755 nm Alexandrite lasers into pig skin according to different fluences and spot diameters, and estimated epidermal/dermal temperatures. Pig skin specimens were stained with hematoxylin and eosin for histological assessments. The fluence conditions comprised 26, 30, and 36 J/cm2, and the spot diameter conditions were 5, 8, and 10 mm. Pulse duration was 30 ms for all experiments. Results: Both lasers produced reliable thermal damage on the dermis without any serious epidermal injuries, under relatively high fluence conditions. The 1064 nm laser provided more active fibrous formations than the 755 nm laser, while higher risks for tissue damages simultaneously occurred. Conclusions: The ideal treatment conditions for skin rejuvenation were 8 mm diameter with 30 J/cm2 and 10 mm diameter with 26 J/cm2 for the 1064 nm laser, and 8 mm diameter with 36 J/cm2 and 10 mm diameter with 26 J/cm2 for the 755 nm laser. PMID:24992273

  16. Comparison of epidermal/dermal damage between the long-pulsed 1064 nm Nd:YAG and 755 nm alexandrite lasers under relatively high fluence conditions: quantitative and histological assessments.

    PubMed

    Lee, Ju Hwan; Park, So Ra; Jo, Jeong Ho; Park, Sung Yun; Seo, Young Kwon; Kim, Sung Min

    2014-07-01

    The purpose of this study was to compare degrees of epidermal/dermal tissue damage quantitatively and histologically after laser irradiation, to find ideal treatment conditions with relatively high fluence for skin rejuvenation. A number of recent studies have evaluated the clinical efficacy and safety of therapeutic lasers under relatively low fluence conditions. We transmitted the long-pulsed 1064 nm Nd:YAG and 755 nm Alexandrite lasers into pig skin according to different fluences and spot diameters, and estimated epidermal/dermal temperatures. Pig skin specimens were stained with hematoxylin and eosin for histological assessments. The fluence conditions comprised 26, 30, and 36 J/cm2, and the spot diameter conditions were 5, 8, and 10 mm. Pulse duration was 30 ms for all experiments. Both lasers produced reliable thermal damage on the dermis without any serious epidermal injuries, under relatively high fluence conditions. The 1064 nm laser provided more active fibrous formations than the 755 nm laser, while higher risks for tissue damages simultaneously occurred. The ideal treatment conditions for skin rejuvenation were 8 mm diameter with 30 J/cm2 and 10 mm diameter with 26 J/cm2 for the 1064 nm laser, and 8 mm diameter with 36 J/cm2 and 10 mm diameter with 26 J/cm2 for the 755 nm laser.

  17. Higher certainty of the laser-induced damage threshold test with a redistributing data treatment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jensen, Lars; Mrohs, Marius; Gyamfi, Mark

    2015-10-15

    As a consequence of its statistical nature, the measurement of the laser-induced damage threshold holds always risks to over- or underestimate the real threshold value. As one of the established measurement procedures, the results of S-on-1 (and 1-on-1) tests outlined in the corresponding ISO standard 21 254 depend on the amount of data points and their distribution over the fluence scale. With the limited space on a test sample as well as the requirements on test site separation and beam sizes, the amount of data from one test is restricted. This paper reports on a way to treat damage testmore » data in order to reduce the statistical error and therefore measurement uncertainty. Three simple assumptions allow for the assignment of one data point to multiple data bins and therefore virtually increase the available data base.« less

  18. Non-thermal damage to lead tungstate induced by intense short-wavelength laser radiation (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Vozda, Vojtech; Boháček, Pavel; Burian, Tomáš; Chalupský, Jaromir; Hájková, Vera; Juha, Libor; Vyšín, Ludek; Gaudin, Jérôme; Heimann, Philip A.; Hau-Riege, Stefan P.; Jurek, Marek; Klinger, Dorota; Krzywinski, Jacek; Messerschmidt, Marc; Moeller, Stefan P.; Nagler, Robert; Pelka, Jerzy B.; Rowen, Michael; Schlotter, William F.; Swiggers, Michele L.; Sinn, Harald; Sobierajski, Ryszard; Tiedtke, Kai; Toleikis, Sven; Tschentscher, Thomas; Turner, Joshua J.; Wabnitz, Hubertus; Nelson, Art J.; Kozlova, Maria V.; Vinko, Sam M.; Whitcher, Thomas; Dzelzainis, Thomas; Renner, Oldrich; Saksl, Karel; Fäustlin, Roland R.; Khorsand, Ali R.; Fajardo, Marta; Iwan, Bianca S.; Andreasson, Jakob; Hajdu, Janos; Timneanu, Nicusor; Wark, Justin S.; Riley, David; Lee, Richard W.; Nagasono, Mitsuru; Yabashi, Makina

    2017-05-01

    Interaction of short-wavelength free-electron laser (FEL) beams with matter is undoubtedly a subject to extensive investigation in last decade. During the interaction various exotic states of matter, such as warm dense matter, may exist for a split second. Prior to irreversible damage or ablative removal of the target material, complicated electronic processes at the atomic level occur. As energetic photons impact the target, electrons from inner atomic shells are almost instantly photo-ionized, which may, in some special cases, cause bond weakening, even breaking of the covalent bonds, subsequently result to so-called non-thermal melting. The subject of our research is ablative damage to lead tungstate (PbWO4) induced by focused short-wavelength FEL pulses at different photon energies. Post-mortem analysis of complex damage patterns using the Raman spectroscopy, atomic-force (AFM) and Nomarski (DIC) microscopy confirms an existence of non-thermal melting induced by high-energy photons in the ionic monocrystalline target. Results obtained at Linac Coherent Light Source (LCLS), Free-electron in Hamburg (FLASH), and SPring-8 Compact SASE Source (SCSS) are presented in this Paper.

  19. Experimental study of EUV mirror radiation damage resistance under long-term free-electron laser exposures below the single-shot damage threshold

    PubMed Central

    Makhotkin, Igor A.; Sobierajski, Ryszard; Chalupský, Jaromir; Tiedtke, Kai; de Vries, Gosse; Störmer, Michael; Scholze, Frank; Siewert, Frank; van de Kruijs, Robbert W. E.; Milov, Igor; Louis, Eric; Jacyna, Iwanna; Jurek, Marek; Klinger, Dorota; Syryanyy, Yevgen; Juha, Libor; Hájková, Věra; Saksl, Karel; Faatz, Bart; Keitel, Barbara; Plönjes, Elke; Toleikis, Sven; Loch, Rolf; Hermann, Martin; Strobel, Sebastian; Nienhuys, Han-Kwang; Gwalt, Grzegorz; Mey, Tobias; Enkisch, Hartmut

    2018-01-01

    The durability of grazing- and normal-incidence optical coatings has been experimentally assessed under free-electron laser irradiation at various numbers of pulses up to 16 million shots and various fluence levels below 10% of the single-shot damage threshold. The experiment was performed at FLASH, the Free-electron LASer in Hamburg, using 13.5 nm extreme UV (EUV) radiation with 100 fs pulse duration. Polycrystalline ruthenium and amorphous carbon 50 nm thin films on silicon substrates were tested at total external reflection angles of 20° and 10° grazing incidence, respectively. Mo/Si periodical multilayer structures were tested in the Bragg reflection condition at 16° off-normal angle of incidence. The exposed areas were analysed post-mortem using differential contrast visible light microscopy, EUV reflectivity mapping and scanning X-ray photoelectron spectroscopy. The analysis revealed that Ru and Mo/Si coatings exposed to the highest dose and fluence level show a few per cent drop in their EUV reflectivity, which is explained by EUV-induced oxidation of the surface. PMID:29271755

  20. Experimental study of EUV mirror radiation damage resistance under long-term free-electron laser exposures below the single-shot damage threshold.

    PubMed

    Makhotkin, Igor A; Sobierajski, Ryszard; Chalupský, Jaromir; Tiedtke, Kai; de Vries, Gosse; Störmer, Michael; Scholze, Frank; Siewert, Frank; van de Kruijs, Robbert W E; Milov, Igor; Louis, Eric; Jacyna, Iwanna; Jurek, Marek; Klinger, Dorota; Nittler, Laurent; Syryanyy, Yevgen; Juha, Libor; Hájková, Věra; Vozda, Vojtěch; Burian, Tomáš; Saksl, Karel; Faatz, Bart; Keitel, Barbara; Plönjes, Elke; Schreiber, Siegfried; Toleikis, Sven; Loch, Rolf; Hermann, Martin; Strobel, Sebastian; Nienhuys, Han Kwang; Gwalt, Grzegorz; Mey, Tobias; Enkisch, Hartmut

    2018-01-01

    The durability of grazing- and normal-incidence optical coatings has been experimentally assessed under free-electron laser irradiation at various numbers of pulses up to 16 million shots and various fluence levels below 10% of the single-shot damage threshold. The experiment was performed at FLASH, the Free-electron LASer in Hamburg, using 13.5 nm extreme UV (EUV) radiation with 100 fs pulse duration. Polycrystalline ruthenium and amorphous carbon 50 nm thin films on silicon substrates were tested at total external reflection angles of 20° and 10° grazing incidence, respectively. Mo/Si periodical multilayer structures were tested in the Bragg reflection condition at 16° off-normal angle of incidence. The exposed areas were analysed post-mortem using differential contrast visible light microscopy, EUV reflectivity mapping and scanning X-ray photoelectron spectroscopy. The analysis revealed that Ru and Mo/Si coatings exposed to the highest dose and fluence level show a few per cent drop in their EUV reflectivity, which is explained by EUV-induced oxidation of the surface.

  1. Damage threshold from large retinal spot size repetitive-pulse laser exposures.

    PubMed

    Lund, Brian J; Lund, David J; Edsall, Peter R

    2014-10-01

    The retinal damage thresholds for large spot size, multiple-pulse exposures to a Q-switched, frequency doubled Nd:YAG laser (532 nm wavelength, 7 ns pulses) have been measured for 100 μm and 500 μm retinal irradiance diameters. The ED50, expressed as energy per pulse, varies only weakly with the number of pulses, n, for these extended spot sizes. The previously reported threshold for a multiple-pulse exposure for a 900 μm retinal spot size also shows the same weak dependence on the number of pulses. The multiple-pulse ED50 for an extended spot-size exposure does not follow the n dependence exhibited by small spot size exposures produced by a collimated beam. Curves derived by using probability-summation models provide a better fit to the data.

  2. Damage threshold of platinum coating used for optics for self-seeding of soft x-ray free electron laser

    DOE PAGES

    Krzywinski, Jacek; Cocco, Daniele; Moeller, Stefan; ...

    2015-02-23

    We investigated the experimental damage threshold of platinum coating on a silicon substrate illuminated by soft x-ray radiation at grazing incidence angle of 2.1 deg. The coating was the same as the blazed grating used for the soft X-ray self-seeding optics of the Linac Coherent Light Source free electron laser. The irradiation condition was chosen such that the absorbed dose was similar to the maximum dose expected for the grating. The expected dose was simulated by solving the Helmholtz equation in non-homogenous media. The experiment was performed at 900 eV photon energy for both single pulse and multi-shot conditions. Wemore » have not observed single shot damage. This corresponds to a single shot damage threshold being higher than 3 J/cm 2. The multiple shot damage threshold measured for 10 shots and about 600 shots was determined to be 0.95 J/cm 2 and 0.75 J/cm 2 respectively. The damage threshold occurred at an instantaneous dose which is higher that the melt dose of platinum.« less

  3. How reduced vacuum pumping capability in a coating chamber affects the laser damage resistance of HfO 2/SiO 2 antireflection and high-reflection coatings

    DOE PAGES

    Field, Ella S.; Bellum, John C.; Kletecka, Damon E.

    2016-07-15

    Here, optical coatings with the highest laser damage thresholds rely on clean conditions in the vacuum chamber during the coating deposition process. A low-base pressure in the coating chamber, as well as the ability of the vacuum system to maintain the required pressure during deposition, are important aspects of limiting the amount of defects in an optical coating that could induce laser damage. Our large optics coating chamber at Sandia National Laboratories normally relies on three cryo pumps to maintain low pressures for e-beam coating processes. However, on occasion, one or more of the cryo pumps have been out ofmore » commission. In light of this circumstance, we explored how deposition under compromised vacuum conditions resulting from the use of only one or two cryo pumps affects the laser-induced damage thresholds of optical coatings. The coatings of this study consist of HfO 2 and SiO 2 layer materials and include antireflection coatings for 527 nm at normal incidence and high-reflection coatings for 527 nm at 45-deg angle of incidence in P-polarization.« less

  4. Quantifying Seasonal Skill in Coupled Sea Ice Models using Freeboard Measurements from Spaceborne Laser Altimeters

    NASA Astrophysics Data System (ADS)

    Roberts, A.; Bench, K.; Maslowski, W.; Farrell, S. L.; Richter-Menge, J.

    2016-12-01

    We have developed a method to quantitatively assess the skill of predictive sea ice models using freeboard measurements from spaceborne laser altimeters. The method evaluates freeboard from the Regional Arctic System Model (RASM) against those derived from NASA ICESat and Operation IceBridge (OIB) missions along individual ground tracks, and assesses the variance- and correlation-weighted model skill. This allows quantifying the accuracy of sea ice volume simulations and taking measurement error into account. As part of this work, we inter-compare simulations with two different sea ice rheologies: one using Elastic-Viscous-Plastic (EVP), and the other using Elastic-Anisotropic-Plastic (EAP) ice mechanics. Both are simulated for 2004 and 2007, during which ICESat was in operation. RASM variance skill scores ranged from 0.712 to 0.824 and correlation skill scores were between 0.319 and 0.511, with EAP providing a better estimate of spatial ice volume variance, but with a larger bias in the central Arctic relative to EVP. The skill scores were calculated for monthly periods and require little adaption to rate short-term operational forecasts of the Arctic. This work will help quantify model limitations and facilitate optimal use of ICESat-2 freeboard measurements after that satellite is launched next year.

  5. Laser pointers: toys, nuisances, or significant eye hazards?

    PubMed

    Yolton, R L; Citek, K; Schmeisser, E; Reichow, A W; Griffith, T

    1999-05-01

    Laser pointers have been used inappropriately to harass and "dazzle" victims. Reports of retinal damage caused by pointers have also been circulated in the popular press. Information on pointer abuse was collected from the literature and through discussions with specialists. Few, if any, documented cases of permanent retinal damage caused by laser pointers could be found. For actual damage to occur, viewing, times need to exceed approximately 10 seconds. Exposures of this duration would require the person being lased to cooperate by holding fixation on the laser beam. Although the risk of permanent retinal damage from a laser-pointer beam is minimal, other risks include dazzle, annoyance, and concern that a weapon-aiming device rather than a pointer is generating the laser beam.

  6. Effect of Heat Input on the Tensile Damage Evolution in Pulsed Laser Welded Ti6Al4V Titanium Sheets

    NASA Astrophysics Data System (ADS)

    Liu, Jing; Gao, Xiaolong; Zhang, Jianxun

    2016-11-01

    The present paper is focused on studying the effect of heat input on the tensile damage evolution of pulsed Nd:YAG laser welding of Ti6Al4V alloy under monotonic loading. To analyze the reasons that the tensile fracture site of the pulsed-laser-welded Ti6Al4V sheet joints changes with the heat input under monotonic loading, the microstructure of the sample with different nominal strain values was investigated by in situ observation. Experiment results show that the tensile ductility and fatigue life of welded joints with low heat input are higher than that of welded joints with high heat input. Under tensile loads, the critical engineering strain for crack initiation is much lower in the welded joint with high heat input than in the welded joints with low and medium heat input. And the microstructural damage accumulation is much faster in the fusion zone than in the base metal for the welded joints with high input, whereas the microstructural damage accumulation is much faster in the base metal than in the fusion zone for the welded joints with low input. Consequently, the welded joints fractured in the fusion zone for the welds with high heat input, whereas the welded joints ruptured in the base metal for the welds with low heat input. It is proved that the fine grain microstructure produced by low heat input can improve the critical nominal strain for crack initiation and the resistance ability of microstructural damage.

  7. Laser damage properties of TiO{sub 2}/Al{sub 2}O{sub 3} thin films grown by atomic layer deposition

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wei Yaowei; Liu Hao; Sheng Ouyang

    2011-08-20

    Research on thin film deposited by atomic layer deposition (ALD) for laser damage resistance is rare. In this paper, it has been used to deposit TiO{sub 2}/Al{sub 2}O{sub 3} films at 110 deg. C and 280 deg. C on fused silica and BK7 substrates. Microstructure of the thin films was investigated by x-ray diffraction. The laser-induced damage threshold (LIDT) of samples was measured by a damage test system. Damage morphology was studied under a Nomarski differential interference contrast microscope and further checked under an atomic force microscope. Multilayers deposited at different temperatures were compared. The results show that the filmsmore » deposited by ALD had better uniformity and transmission; in this paper, the uniformity is better than 99% over 100 mm {Phi} samples, and the transmission is more than 99.8% at 1064 nm. Deposition temperature affects the deposition rate and the thin film microstructure and further influences the LIDT of the thin films. As to the TiO{sub 2}/Al{sub 2}O{sub 3} films, the LIDTs were 6.73{+-}0.47 J/cm{sup 2} and 6.5{+-}0.46 J/cm{sup 2} at 110 deg. C on fused silica and BK7 substrates, respectively. The LIDTs at 110 deg. C are notably better than 280 deg. C.« less

  8. OCDR guided laser ablation device

    DOEpatents

    Dasilva, Luiz B.; Colston, Jr., Bill W.; James, Dale L.

    2002-01-01

    A guided laser ablation device. The device includes a mulitmode laser ablation fiber that is surrounded by one or more single mode optical fibers that are used to image in the vicinity of the laser ablation area to prevent tissue damage. The laser ablation device is combined with an optical coherence domain reflectometry (OCDR) unit and with a control unit which initializes the OCDR unit and a high power laser of the ablation device. Data from the OCDR unit is analyzed by the control unit and used to control the high power laser. The OCDR images up to about 3 mm ahead of the ablation surface to enable a user to see sensitive tissue such as a nerve or artery before damaging it by the laser.

  9. Optical damage testing at the Z-Backlighter facility at Sandia National Laboratories

    NASA Astrophysics Data System (ADS)

    Kimmel, Mark; Rambo, Patrick; Broyles, Robin; Geissel, Matthias; Schwarz, Jens; Bellum, John; Atherton, Briggs

    2009-10-01

    To enable laser-based radiography of high energy density physics events on the Z-Accelerator[4,5] at Sandia National Laboratories, a facility known as the Z-Backlighter has been developed. Two Nd:Phosphate glass lasers are used to create x-rays and/or proton beams capable of this radiographic diagnosis: Z-Beamlet (a multi-kilojoule laser operating at 527nm in a few nanoseconds) and Z-Petawatt (a several hundred joule laser operating at 1054nm in the subpicosecond regime) [1,2]. At the energy densities used in these systems, it is necessary to use high damage threshold optical materials, some of which are poorly characterized (especially for the sub-picosecond pulse). For example, Sandia has developed a meter-class dielectric coating capability for system optics. Damage testing can be performed by external facilities for nanosecond 532nm pulses, measuring high reflector coating damage thresholds >80J/cm2 and antireflection coating damage thresholds >20J/cm2 [3]. However, available external testing capabilities do not use femtosecond/picosecond scale laser pulses. To this end, we have constructed a sub-picoseond-laser-based optical damage test system. The damage tester system also allows for testing in a vacuum vessel, which is relevant since many optics in the Z-Backlighter system are used in vacuum. This paper will present the results of laser induced damage testing performed in both atmosphere and in vacuum, with 1054nm sub-picosecond laser pulses. Optical materials/coatings discussed are: bare fused silica and protected gold used for benchmarking; BK7; Zerodur; protected silver; and dielectric optical coatings (halfnia/silica layer pairs) produced by Sandia's in-house meter-class coating capability.

  10. History of Laser Weapon Research

    DTIC Science & Technology

    2012-01-01

    designed to damage, disable, or destroy targets with little or no collateral damage. Airborne Laser (ABL) (CO2) Chemical Oxygen The ABL C-130H aircraft ...mirrors. Weapons systems based on lasers and “ray guns,” long a staple of science fiction, have captured the imagination of people everywhere. But...waves (millimeters to centimeters), with wavelengths 10,000 times longer than lasers. Diffraction of any electromagnetic radia- tion beam is based

  11. Optimization design and laser damage threshold analysis of pulse compression multilayer dielectric gratings

    NASA Astrophysics Data System (ADS)

    Fan, Shuwei; Bai, Liang; Chen, Nana

    2016-08-01

    As one of the key elements of high-power laser systems, the pulse compression multilayer dielectric grating is required for broader band, higher diffraction efficiency and higher damage threshold. In this paper, the multilayer dielectric film and the multilayer dielectric gratings(MDG) were designed by eigen matrix and optimized with the help of generic algorithm and rigorous coupled wave method. The reflectivity was close to 100% and the bandwith were over 250nm, twice compared to the unoptimized film structure. The simulation software of standing wave field distribution within MDG was developed and the electric field of the MDG was calculated. And the key parameters which affected the electric field distribution were also studied.

  12. The pulsed dye laser versus the Q-switched Nd:YAG laser in laser-induced shock-wave lithotripsy.

    PubMed

    Thomas, S; Pensel, J; Engelhardt, R; Meyer, W; Hofstetter, A G

    1988-01-01

    To date, there are two fairly well-established alternatives for laser-induced shock-wave lithotripsy in clinical practice. The Q-switched Nd:YAG laser is distinguished by the high-stone selectivity of its coupler systems. The necessity of a coupler system and its fairly small conversion rate of light energy into mechanical energy present serious drawbacks. Furthermore, the minimal outer diameter of the transmission system is 1.8 mm. The pulsed-dye laser can be used with a highly flexible and uncomplicated 200-micron fiber. However, the laser system itself is more complicated than the Q-switched Nd:YAG laser and requires a great deal of maintenance. Biological evaluation of damage caused by direct irradiation shows that both laser systems produce minor damage of different degrees. YAG laser lithotripsy with the optomechanical coupler was assessed in 31 patients with ureteral calculi. The instability and limited effectiveness of the fiber application system necessitated auxiliary lithotripsy methods in 14 cases. Dye-laser lithotripsy is currently being tested in clinical application. Further development, such as systems for blind application or electronic feedback mechanisms to limit adverse tissue effects, have yet to be optimized. Nevertheless, laser-induced shock-wave lithotripsy has the potential to become a standard procedure in the endourologic management of stone disease.

  13. Structural damage diagnostics via wave propagation-based filtering techniques

    NASA Astrophysics Data System (ADS)

    Ayers, James T., III

    Structural health monitoring (SHM) of aerospace components is a rapidly emerging field due in part to commercial and military transport vehicles remaining in operation beyond their designed life cycles. Damage detection strategies are sought that provide real-time information of the structure's integrity. One approach that has shown promise to accurately identify and quantify structural defects is based on guided ultrasonic wave (GUW) inspections, where low amplitude attenuation properties allow for long range and large specimen evaluation. One drawback to GUWs is that they exhibit a complex multi-modal response, such that each frequency corresponds to at least two excited modes, and thus intelligent signal processing is required for even the simplest of structures. In addition, GUWs are dispersive, whereby the wave velocity is a function of frequency, and the shape of the wave packet changes over the spatial domain, requiring sophisticated detection algorithms. Moreover, existing damage quantification measures are typically formulated as a comparison of the damaged to undamaged response, which has proven to be highly sensitive to changes in environment, and therefore often unreliable. As a response to these challenges inherent to GUW inspections, this research develops techniques to locate and estimate the severity of the damage. Specifically, a phase gradient based localization algorithm is introduced to identify the defect position independent of excitation frequency and damage size. Mode separation through the filtering technique is central in isolating and extracting single mode components, such as reflected, converted, and transmitted modes that may arise from the incident wave impacting a damage. Spatially-integrated single and multiple component mode coefficients are also formulated with the intent to better characterize wave reflections and conversions and to increase the signal to noise ratios. The techniques are applied to damaged isotropic finite

  14. Method to reduce damage to backing plate

    DOEpatents

    Perry, Michael D.; Banks, Paul S.; Stuart, Brent C.

    2001-01-01

    The present invention is a method for penetrating a workpiece using an ultra-short pulse laser beam without causing damage to subsequent surfaces facing the laser. Several embodiments are shown which place holes in fuel injectors without damaging the back surface of the sack in which the fuel is ejected. In one embodiment, pulses from an ultra short pulse laser remove about 10 nm to 1000 nm of material per pulse. In one embodiment, a plasma source is attached to the fuel injector and initiated by common methods such as microwave energy. In another embodiment of the invention, the sack void is filled with a solid. In one other embodiment, a high viscosity liquid is placed within the sack. In general, high-viscosity liquids preferably used in this invention should have a high damage threshold and have a diffusing property.

  15. Laser Wire Stripper

    NASA Technical Reports Server (NTRS)

    1983-01-01

    NASA-developed space shuttle technology is used in a laser wire stripper designed by Raytheon Company. Laser beams cut through insulation on a wire without damaging conductive metal, because laser radiation that melts plastic insulation is reflected by the metal. The laser process is fast, clean, precise and repeatable. It eliminates quality control problems and the expense of rejected wiring.

  16. Femtosecond laser corneal surgery with in situ determination of the laser attenuation and ablation threshold by second harmonic generation

    NASA Astrophysics Data System (ADS)

    Plamann, Karsten; Nuzzo, Valeria; Albert, Olivier; Mourou, Gérard A.; Savoldelli, Michèle; Dagonet, Françoise; Donate, David; Legeais, Jean-Marc

    2007-02-01

    Femtosecond lasers start to be routinely used in refractive eye surgery. Current research focuses on their application to glaucoma and cataract surgery as well as cornea transplant procedures. To avoid unwanted tissue damage during the surgical intervention it is of utmost importance to maintain a working energy just above the ablation threshold and maintain the laser energy at this working point independently of the local and global tissue properties. To quantify the attenuation of the laser power density in the tissue by absorption, scattering and modification of the point spread function we monitor the second harmonic radiation generated in the collagen matrix of the cornea when exposed to ultrashort laser pulses. We use a CPA system with a regenerative amplifier delivering pulses at a wavelength of 1.06 μm, pulse durations of 400 fs and a maximum energy of 60 μJ. The repetition rate is adjustable from single shot up to 10 kHz. The experiments are performed on human corneas provided by the French Eye bank. To capture the SHG radiation we use a photomultiplier tube connected to a lockin amplifier tuned to the laser repetition rate. The measured data indicates an exponential decay of the laser beam intensity in the volume of the sample and allows for the quantification of the attenuation coefficient and its correlation with the optical properties of the cornea. Complementary analyses were performed on the samples by ultrastructural histology.

  17. Probability of growth of small damage sites on the exit surface of fused silica optics.

    PubMed

    Negres, Raluca A; Abdulla, Ghaleb M; Cross, David A; Liao, Zhi M; Carr, Christopher W

    2012-06-04

    Growth of laser damage on fused silica optical components depends on several key parameters including laser fluence, wavelength, pulse duration, and site size. Here we investigate the growth behavior of small damage sites on the exit surface of SiO₂ optics under exposure to tightly controlled laser pulses. Results demonstrate that the onset of damage growth is not governed by a threshold, but is probabilistic in nature and depends both on the current size of a damage site and the laser fluence to which it is exposed. We also develop models for use in growth prediction. In addition, we show that laser exposure history also influences the behavior of individual sites.

  18. Analysis of Depth of Ablation,Thermal Damage, Wound Healing, and Wound Contraction With Erbium YAG Laser in a Yorkshire Pig Model.

    PubMed

    Alsaad, Salman M S; Ross, E Victor; Smith, Wiley J; DeRienzo, Damian P

    2015-11-01

    The erbium YAG laser is commonly used for skin resurfacing. It is known that varying the pulse duration can influence residual thermal damage and wound healing. Our study used a porcine model to evaluate a broad range of settings in a comparison of depth of ablation, depth of residual thermal damage (RTD), and wound contraction employing both a full coverage and fractional hand piece with an erbium YAG laser. The laser delivered an ablative pulse followed by a heating pulse of variable duration using either the full coverage or fractional hand piece. Pulse durations for specific coagulation depths were selected based on existing heat transfer models. The bilateral flanks of a single Yorkshire pig were irradiated. There were 14 treatment groups. 3 sites were treated per group for a total of 42 sites. Two of the 3 sites were for observational assessments and the 3rd site served as a reservoir for biopsies. Biopsy specimens were collected on days 0, 1, 3, 7, 14, and 28. Bleeding, erythema, wound healing, and wound contraction (in the fractional hand piece groups) were assessed. Wound healing is faster for fractional laser skin resurfacing compared with traditional contiguous resurfacing as demonstrated by textural changes and degree of erythema. The laser operator can be confident that the depth of ablation displayed on this system accurately reflects what is occurring in vivo for both confluent and fractional modes. Likewise, the measured degree of coagulation was consistent with panel display settings for the confluent mode. However, the degree of coagulation, as measured by the thickness of residual thermal damage, did not vary significantly between the fractional groups. In other words, the pulse duration of the second (heating) pulse did not impact the degree of coagulation in the fractional mode. There was a 2.3% wound contraction between some groups and a 6.5% wound contraction between other groups. A two way analysis of variance found a statistically

  19. How reduced vacuum pumping capability in a coating chamber affects the laser damage resistance of HfO 2/SiO 2 antireflection and high reflection coatings.

    DOE PAGES

    Field, Ella Suzanne; Bellum, John Curtis; Kletecka, Damon E.

    2016-06-01

    Optical coatings with the highest laser damage thresholds rely on clean conditions in the vacuum chamber during the coating deposition process. A low base pressure in the coating chamber, as well as the ability of the vacuum system to maintain the required pressure during deposition, are important aspects of limiting the amount of defects in an optical coating that could induce laser damage. Our large optics coating chamber at Sandia National Laboratories normally relies on three cryo pumps to maintain low pressures for e-beam coating processes. However, on occasion, one or more of the cryo pumps have been out ofmore » commission. In light of this circumstance, we explored how deposition under compromised vacuum conditions resulting from the use of only one or two cryo pumps affects the laser-induced damage thresholds of optical coatings. Finally, the coatings of this study consist of HfO 2 and SiO 2 layer materials and include antireflection coatings for 527 nm at normal incidence, and high reflection coatings for 527 nm, 45⁰ angle of incidence (AOI), in P-polarization (P-pol).« less

  20. Contamination and UV lasers: lessons learned

    NASA Astrophysics Data System (ADS)

    Daly, John G.

    2015-09-01

    Laser induced damage to optical elements has been a subject of significant research, development, and improvement, since the first lasers were built over the last 50 years. Better materials, with less absorption, impurities, and defects are available, as well as surface coatings with higher laser damage resistance. However, the presence of contamination (particles, surface deposition films, or airborne) can reduce the threshold for damage by several orders of magnitude. A brief review of the anticipated laser energy levels for damage free operation is presented as a lead into the problems associated with contamination for ultraviolet (UV) laser systems. As UV lasers become more common in applications especially in areas such as lithography, these problems have limited reliability and added to costs. This has been characterized as Airborne Molecular Contamination (AMC) in many published reports. Normal engineering guidelines such as screening materials within the optical compartment for low outgassing levels is the first step. The use of the NASA outgassing database (or similar test methods) with low Total Mass Loss (TML) and Condensed Collected Volatiles Collected Mass (CVCM) is a good baseline. Energetic UV photons are capable of chemical bond scission and interaction with surface contaminant or airborne materials results in deposition of obscuring film laser footprints that continue to degrade laser system performance. Laser systems with average powers less than 5 mW have been shown to exhibit aggressive degradation. Lessons learned over the past 15 years with UV laser contamination and steps to reduce risk will be presented.

  1. Total Internal Reflection Microscopy (TIRM) as a nondestructive surface damage assessment tool

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Liao, Z.M.; Cohen, S.J.; Taylor, J.R.

    1994-10-01

    An easy to use, nondestructive, method for evaluating subsurface damage in polished substrates has been established at LLNL. Subsurface damage has been related to laser damage in coated optical components used in high power, high repetition rate laser systems. Total Internal Reflection Microscopy (TIRM) has been shown to be a viable nondestructive technique in analyzing subsurface damage in optical components. A successful TIRM system has been established for evaluating subsurface damage on fused silica components. Laser light scattering from subsurface damage sites is collected through a Nomarski microscope. These images are then captured by a CCD camera for analysis onmore » a computer. A variety of optics, including components with intentional subsurface damage due to grinding and polishing, have been analyzed and their TIRM images compared to an existing destructive etching method. Methods for quantitative measurement of subsurface damage are also discussed.« less

  2. Laboratory investigation of the efficacy of holmium:YAG laser irradiation in removing intracanal debris

    NASA Astrophysics Data System (ADS)

    Nuebler-Moritz, Michael; Gutknecht, Norbert; Sailer, Hermann F.; Hering, Peter; Prettl, Wilhelm

    1997-05-01

    Current endodontic therapy involves debridement and disinfection of the root canal by means of mechanical instrumentation and chemical irrigation. However, several studies have shown that these techniques fail to achieve complete cleansing. Recently, lasers have been suggested for use within root canals. This study was conducted to determine the efficacy of Holmium:YAG laser irradiation in removing intracanal debris and smear layer. Root canal surfaces of freshly-extracted human teeth were exposed to pulsed Ho:YAG laser radiation. Subsequently, laser induced structural changes were investigated using scanning electron microscopy. Temperature measurements during irradiation were performed by means of thermocouples. The result of this survey give a preliminary indication of the ability of the Ho:YAG laser to improve current endodontic treatment survey give a preliminary indication of the ability of the Ho:YAG laser to improve current endodontic treatment modalities. However, limitations exist with regard to circumscribed and well-quantified irradiation of root canal surfaces, due to the lack of perpendicular delivery of the laser beam. Additional studies will be required to develop suitable optical transmission systems, in order to achieve complete cleansing and to avoid damage to the periradicular tissues, respectively.

  3. Human cadaver retina model for retinal heating during corneal surgery with a femtosecond laser

    NASA Astrophysics Data System (ADS)

    Sun, Hui; Fan, Zhongwei; Yun, Jin; Zhao, Tianzhuo; Yan, Ying; Kurtz, Ron M.; Juhasz, Tibor

    2014-02-01

    Femtosecond lasers are widely used in everyday clinical procedures to perform minimally invasive corneal refractive surgery. The intralase femtosecond laser (AMO Corp. Santa Ana, CA) is a common example of such a laser. In the present study a numerical simulation was developed to quantify the temperature rise in the retina during femtosecond intracorneal surgery. Also, ex-vivo retinal heating due to laser irradiation was measured with an infrared thermal camera (Fluke Corp. Everett, WA) as a validation of the simulation. A computer simulation was developed using Comsol Multiphysics to calculate the temperature rise in the cadaver retina during femtosecond laser corneal surgery. The simulation showed a temperature rise of less than 0.3 degrees for realistic pulse energies for the various repetition rates. Human cadaver retinas were irradiated with a 150 kHz Intralase femtosecond laser and the temperature rise was measured withan infrared thermal camera. Thermal camera measurements are in agreement with the simulation. During routine femtosecond laser corneal surgery with normal clinical parameters, the temperature rise is well beneath the threshold for retina damage. The simulation predictions are in agreement with thermal measurements providing a level of experimental validation.

  4. Surface morphology and subsurface damaged layer of various glasses machined by 193-nm ArF excimer laser

    NASA Astrophysics Data System (ADS)

    Liao, Yunn-shiuan; Chen, Ying-Tung; Chao, Choung-Lii; Liu, Yih-Ming

    2005-01-01

    Owing to the high bonding energy, most of the glasses are removed by photo-thermal rather than photo-chemical effect when they are ablated by the 193 or 248nm excimer lasers. Typically, the machined surface is covered by re-deposited debris and the sub-surface, sometimes surface as well, is scattered with micro-cracks introduced by thermal stress generated during the process. This study aimed to investigate the nature and extent of the surface morphology and sub-surface damaged (SSD) layer induced by the laser ablation. The effects of laser parameters such as fluence, shot number and repetition rate on the morphology and SSD were discussed. An ArF excimer laser (193 nm) was used in the present study to machine glasses such as soda-lime, Zerodur and BK-7. It is found that the melt ejection and debris deposition tend to pile up higher and become denser in structure under a higher energy density, repetition rate and shot number. There are thermal stress induced lateral cracks when the debris covered top layer is etched away. Higher fluence and repetition rate tend to generate more lateral and median cracks which propagate into the substrate. The changes of mechanical properties of the SSD layer were also investigated.

  5. Optical damage observed in the LHMEL II output coupler

    NASA Astrophysics Data System (ADS)

    Eric, John J.; Bagford, John O.; Devlin, Christie L. H.; Hull, Robert J.; Seibert, Daniel B.

    2008-01-01

    During the annual NIST calibration testing done at the LHMEL facility in FY06 on its high energy Carbon-Dioxide lasers, the LHMEL II device suffered severe damage to the internal surface of its ZnSe output coupler optics. The damage occurred during a high power, short duration run and it was believed to have been the result of a significant amount of surface contaminants interacting with the LHMEL cavity beam. Initial theories as to the source of the contamination led to the inspection of the vacuum grease that seals the piping that supplies the source gases to the laser cavity. Other contamination sources were considered, and analysis was conducted in an effort to identify the material found at the damage sites on the optic, but the tests were mainly inconclusive. Some procedure changes were initiated to identify possible contamination before high energy laser operation in an attempt to mitigate and possibly prevent the continued occurrence of damage to the output coupler window. This paper is to illustrate the type and extent of the damage encountered, highlight some of the theories as to the contamination source, and serve as a notice as to the severity and consequences of damage that is possible even due to small amounts of foreign material in a high energy laser environment.

  6. High-speed scanning ablation of dental hard tissues with a λ = 9.3 μm CO2 laser: adhesion, mechanical strength, heat accumulation, and peripheral thermal damage

    PubMed Central

    Nguyen, Daniel; Chang, Kwang; Hedayatollahnajafi, Saba; Staninec, Michal; Chan, Kenneth; Lee, Robert; Fried, Daniel

    2011-01-01

    CO2 lasers can be operated at high laser pulse repetition rates for the rapid and precise removal of dental decay. Excessive heat accumulation and peripheral thermal damage is a concern when using high pulse repetition rates. Peripheral thermal damage can adversely impact the mechanical strength of the irradiated tissue, particularly for dentin, and reduce the adhesion characteristics of the modified surfaces. The interpulpal temperature rise was recorded using microthermocouples situated at the roof of the pulp chamber on teeth that were occlusally ablated using a rapidly-scanned CO2 laser operating at 9.3 μm with a pulse duration of 10 to 15 μs and repetition rate of 300 Hz over a 2 min time course. The adhesion strength of laser treated enamel and dentin surfaces was measured for various laser scanning parameters with and without post-ablation acid etching using the single-plane shear test. The mechanical strength of laser-ablated dentin surfaces were determined via the four-point bend test and compared to control samples prepared with 320 grit wet sand paper to simulate conventional preparations. Thermocouple measurements indicated that the temperature remained below ambient temperature if water-cooling was used. There was no discoloration of either dentin or enamel laser treated surfaces, the surfaces were uniformly ablated, and there were no cracks visible. Four-point bend tests yielded mean mechanical strengths of 18.2 N (s.d. = 4.6) for ablated dentin and 18.1 N (s.d. = 2.7) for control (p > 0.05). Shear tests yielded mean bond strengths approaching 30 MPa for both enamel and dentin under certain irradiation conditions. These values were slightly lower than nonirradiated acid-etched control samples. Additional studies are needed to determine if the slightly lower bond strength than the acid-etched control samples is clinically significant. These measurements demonstrate that enamel and dentin surfaces can be rapidly ablated by CO2 lasers with minimal

  7. High-speed scanning ablation of dental hard tissues with a λ = 9.3 μm CO2 laser: adhesion, mechanical strength, heat accumulation, and peripheral thermal damage

    NASA Astrophysics Data System (ADS)

    Nguyen, Daniel; Chang, Kwang; Hedayatollahnajafi, Saba; Staninec, Michal; Chan, Kenneth; Lee, Robert; Fried, Daniel

    2011-07-01

    CO2 lasers can be operated at high laser pulse repetition rates for the rapid and precise removal of dental decay. Excessive heat accumulation and peripheral thermal damage is a concern when using high pulse repetition rates. Peripheral thermal damage can adversely impact the mechanical strength of the irradiated tissue, particularly for dentin, and reduce the adhesion characteristics of the modified surfaces. The interpulpal temperature rise was recorded using microthermocouples situated at the roof of the pulp chamber on teeth that were occlusally ablated using a rapidly-scanned CO2 laser operating at 9.3 μm with a pulse duration of 10 to 15 μs and repetition rate of 300 Hz over a 2 min time course. The adhesion strength of laser treated enamel and dentin surfaces was measured for various laser scanning parameters with and without post-ablation acid etching using the single-plane shear test. The mechanical strength of laser-ablated dentin surfaces were determined via the four-point bend test and compared to control samples prepared with 320 grit wet sand paper to simulate conventional preparations. Thermocouple measurements indicated that the temperature remained below ambient temperature if water-cooling was used. There was no discoloration of either dentin or enamel laser treated surfaces, the surfaces were uniformly ablated, and there were no cracks visible. Four-point bend tests yielded mean mechanical strengths of 18.2 N (s.d. = 4.6) for ablated dentin and 18.1 N (s.d. = 2.7) for control (p > 0.05). Shear tests yielded mean bond strengths approaching 30 MPa for both enamel and dentin under certain irradiation conditions. These values were slightly lower than nonirradiated acid-etched control samples. Additional studies are needed to determine if the slightly lower bond strength than the acid-etched control samples is clinically significant. These measurements demonstrate that enamel and dentin surfaces can be rapidly ablated by CO2 lasers with minimal

  8. High-speed scanning ablation of dental hard tissues with a λ = 9.3 μm CO2 laser: adhesion, mechanical strength, heat accumulation, and peripheral thermal damage.

    PubMed

    Nguyen, Daniel; Chang, Kwang; Hedayatollahnajafi, Saba; Staninec, Michal; Chan, Kenneth; Lee, Robert; Fried, Daniel

    2011-07-01

    CO(2) lasers can be operated at high laser pulse repetition rates for the rapid and precise removal of dental decay. Excessive heat accumulation and peripheral thermal damage is a concern when using high pulse repetition rates. Peripheral thermal damage can adversely impact the mechanical strength of the irradiated tissue, particularly for dentin, and reduce the adhesion characteristics of the modified surfaces. The interpulpal temperature rise was recorded using microthermocouples situated at the roof of the pulp chamber on teeth that were occlusally ablated using a rapidly-scanned CO(2) laser operating at 9.3 μm with a pulse duration of 10 to 15 μs and repetition rate of 300 Hz over a 2 min time course. The adhesion strength of laser treated enamel and dentin surfaces was measured for various laser scanning parameters with and without post-ablation acid etching using the single-plane shear test. The mechanical strength of laser-ablated dentin surfaces were determined via the four-point bend test and compared to control samples prepared with 320 grit wet sand paper to simulate conventional preparations. Thermocouple measurements indicated that the temperature remained below ambient temperature if water-cooling was used. There was no discoloration of either dentin or enamel laser treated surfaces, the surfaces were uniformly ablated, and there were no cracks visible. Four-point bend tests yielded mean mechanical strengths of 18.2 N (s.d. = 4.6) for ablated dentin and 18.1 N (s.d. = 2.7) for control (p > 0.05). Shear tests yielded mean bond strengths approaching 30 MPa for both enamel and dentin under certain irradiation conditions. These values were slightly lower than nonirradiated acid-etched control samples. Additional studies are needed to determine if the slightly lower bond strength than the acid-etched control samples is clinically significant. These measurements demonstrate that enamel and dentin surfaces can be rapidly ablated by CO(2) lasers with

  9. Corneal and skin laser exposures from 1540-nm laser pulses

    NASA Astrophysics Data System (ADS)

    Johnson, Thomas E.; Mitchell, Michael A.; Rico, Pedro J.; Fletcher, David J.; Eurell, Thomas E.; Roach, William P.

    2000-06-01

    Mechanisms of tissue damage are investigated for skin and cornea exposures from 1540 nm ('eye safe') laser single pulses of 0.8 milli-seconds. New skin model data point out the advantages of using the Yucatan mini-pig versus the Yorkshire pig for in-vivo skin laser exposures. Major advantages found include similarities in thickness and melanin content when compared with human skin. Histology from Yucatan mini-pig skin exposures and the calculation of an initial ED50 threshold indicate that the main photon tissue interaction may not be solely due to water absorption. In-vitro corneal equivalents compared well with in-vivo rabbit cornea exposure under similar laser conditions. In-vivo and in-vitro histology show that initial energy deposition leading to damage occurs intrastromally, while epithelial cells show no direct injury due to laser light absorption.

  10. Mechanisms of Retinal Damage from Chronic Laser Radiation.

    DTIC Science & Technology

    1981-07-01

    culture. The pigment epithelium is deter- mined to be almost equally susceptible to damage in vitro as in vivo and the same action spectrum is similar in...92 -97 D. Experiment III. Light Damage in Culture of Bovine Retinal Pigment Epithelium 1. Methodology a. Collection of Cells... epithelium : Mild form of damage. Figure 18 Inner segments severely damaged. Figure 19 : Cone pedicle after exposure. Figure 20 Outer plexiform layer

  11. Crop Damage by Primates: Quantifying the Key Parameters of Crop-Raiding Events

    PubMed Central

    Wallace, Graham E.; Hill, Catherine M.

    2012-01-01

    Human-wildlife conflict often arises from crop-raiding, and insights regarding which aspects of raiding events determine crop loss are essential when developing and evaluating deterrents. However, because accounts of crop-raiding behaviour are frequently indirect, these parameters are rarely quantified or explicitly linked to crop damage. Using systematic observations of the behaviour of non-human primates on farms in western Uganda, this research identifies number of individuals raiding and duration of raid as the primary parameters determining crop loss. Secondary factors include distance travelled onto farm, age composition of the raiding group, and whether raids are in series. Regression models accounted for greater proportions of variation in crop loss when increasingly crop and species specific. Parameter values varied across primate species, probably reflecting differences in raiding tactics or perceptions of risk, and thereby providing indices of how comfortable primates are on-farm. Median raiding-group sizes were markedly smaller than the typical sizes of social groups. The research suggests that key parameters of raiding events can be used to measure the behavioural impacts of deterrents to raiding. Furthermore, farmers will benefit most from methods that discourage raiding by multiple individuals, reduce the size of raiding groups, or decrease the amount of time primates are on-farm. This study demonstrates the importance of directly relating crop loss to the parameters of raiding events, using systematic observations of the behaviour of multiple primate species. PMID:23056378

  12. Picosecond lasers: the next generation of short-pulsed lasers.

    PubMed

    Freedman, Joshua R; Kaufman, Joely; Metelitsa, Andrea I; Green, Jeremy B

    2014-12-01

    Selective photothermolysis, first discussed in the context of targeted microsurgery in 1983, proposed that the optimal parameters for specific thermal damage rely critically on the duration over which energy is delivered to the tissue. At that time, nonspecific thermal damage had been an intrinsic limitation of all commercially available lasers, despite efforts to mitigate this by a variety of compensatory cooling mechanisms. Fifteen years later, experimental picosecond lasers were first reported in the dermatological literature to demonstrate greater efficacy over their nanosecond predecessors in the context of targeted destruction of tattoo ink. Within the last 4 years, more than a decade after those experiments, the first commercially available cutaneous picosecond laser unit became available (Cynosure, Westford, Massachusetts), and several pilot studies have demonstrated its utility in tattoo removal. An experimental picosecond infrared laser has also recently demonstrated a nonthermal tissue ablative capability in soft tissue, bone, and dentin. In this article, we review the published data pertaining to dermatology on picosecond lasers from their initial reports to the present as well as discuss forthcoming technology.

  13. Photothermal and photoacoustic processes of laser activated nano-thermolysis of cells

    NASA Astrophysics Data System (ADS)

    Lapotko, Dmitri; Lukianova, Ekaterina; Mitskevich, Pavel; Smolnikova, Victoria; Potapnev, Michail; Konopleva, Marina; Andreeff, Michael; Oraevsky, Alexander

    2007-02-01

    Laser Activated Nano-Thermolysis was recently proposed for selective damage of individual target (cancer) cells by pulsed laser induced microbubbles around superheated clusters of optically absorbing nanoparticles (NP). One of the clinical applications of this technology is the elimination of residual tumor cells from human blood and bone marrow. Clinical standards for the safety and efficacy of such procedure require the development and verification of highly selective and controllable mechanisms of cell killing. Our previous experiments showed that laser-induced microbubble is the main damaging factor in the case cell irradiation by short laser pulses above the threshold. Our current aim was to study the cell damage mechanisms and analyze selectivity and efficacy of cell damage as a function of NP parameters, NP-cell interaction conditions, and conditions of bubble generation around NP and NP clusters in cells. Generation of laser-induced bubbles around gold NP with diameters 10-250 nm was studied in Acute Myeloblast Leukemia (AML) cultures, normal stem and model K562 human cells. Short laser pulses (10 ns, 532 nm) were applied to those cells in vitro and the processes in cells were investigated with photothermal, fluorescent and atomic force microscopies and also with fluorescence flow cytometry. We have found that the best selectivity of cell damage is achieved by (1) forming large clusters of optically absorbing NP in target cells and (2) irradiating the cells with single laser pulses with the lowest fluence that can generate microbubble only around large clusters but not around single NP. Laser microbubbles with the lifetime from 20 ns to 2000 ns generated in individual cells caused damage and lysis of the cellular membrane and consequently cell death. Laser microbubbles did not damage normal cells around the damaged target (tumor) cell. Laser irradiation with equal fluence did not cause any damage of cells without accumulated NP clusters.

  14. Assessment of multi-pulse laser-induced damage threshold of metallic mirrors for Thomson scattering system.

    PubMed

    Sato, Masaya; Kajita, Shin; Yasuhara, Ryo; Ohno, Noriyasu; Tokitani, Masayuki; Yoshida, Naoaki; Tawara, Yuzuru

    2013-04-22

    Multi-pulse laser-induced damage threshold (LIDT) was experimentally investigated up to ~10(6) pulses for Cu, Ag mirrors. The surface roughness and the hardness dependence on the LIDT were also examined. The LIDT of OFHC-Cu decreased with the pulse number and was 1.0 J/cm(2) at 1.8 × 10(6) pulses. The expected LIDT of cutting Ag at 10(7) pulses was the highest; Ag mirror would be one of the best choices for ITER Thomson scattering system. For the roughness and hardness, material dependences of LIDT are discussed with experimental results.

  15. Scanning fluorescence correlation spectroscopy techniques to quantify the kinetics of DNA double strand break repair proteins after γ-irradiation and bleomycin treatment

    PubMed Central

    Abdisalaam, Salim; Davis, Anthony J.; Chen, David J.; Alexandrakis, George

    2014-01-01

    A common feature of DNA repair proteins is their mobilization in response to DNA damage. The ability to visualizing and quantifying the kinetics of proteins localizing/dissociating from DNA double strand breaks (DSBs) via immunofluorescence or live cell fluorescence microscopy have been powerful tools in allowing insight into the DNA damage response, but these tools have some limitations. For example, a number of well-established DSB repair factors, in particular those required for non-homologous end joining (NHEJ), do not form discrete foci in response to DSBs induced by ionizing radiation (IR) or radiomimetic drugs, including bleomycin, in living cells. In this report, we show that time-dependent kinetics of the NHEJ factors Ku80 and DNA-dependent protein kinase catalytic subunits (DNA–PKcs) in response to IR and bleomycin can be quantified by Number and Brightness analysis and Raster-scan Image Correlation Spectroscopy. Fluorescent-tagged Ku80 and DNA–PKcs quickly mobilized in response to IR and bleomycin treatments consistent with prior reports using laser-generated DSBs. The response was linearly dependent on IR dose, and blocking NHEJ enhanced immobilization of both Ku80 and DNA–PKcs after DNA damage. These findings support the idea of using Number and Brightness and Raster-scan Image Correlation Spectroscopy as methods to monitor kinetics of DSB repair proteins in living cells under conditions mimicking radiation and chemotherapy treatments. PMID:24137007

  16. A developmental perspective on high power laser facility technology for ICF

    NASA Astrophysics Data System (ADS)

    Zhu, Jianqiang; Sun, Mingying; Liu, Chong; Guo, Yajing; Yang, Lin; Yang, Pengqian; Zhang, Yanli; Wang, Bingyan; Liu, Cheng; Li, Yangshuai; Ren, Zhiyuan; Liu, Dean; Liu, Zhigang; Jiao, Zhaoyang; Ren, Lei; Zhang, Guowen; Fan, Quantang; Feng, Tao; Lin, Zunqi

    2018-02-01

    The latest progress on high power laser facilities in NLHPLP was reported. Based on a high power laser prototype, damage behavior of 3ω optics was experimentally tested, and the key influencing factors contributed to laser-induced damage in optics were deeply analyzed. The latest experimental results of advanced precision measurement for optical quality applied in the high power laser facility were introduced. At last, based on the accumulated works of 3ω elements damage behavior status in our laboratory, beam expanding scheme was presented to increase the total maximum output 3ω energy properly and decrease the laser induced damage risking of ω optics simultaneously.

  17. Identification of damage in plates using full-field measurement with a continuously scanning laser Doppler vibrometer system

    NASA Astrophysics Data System (ADS)

    Chen, Da-Ming; Xu, Y. F.; Zhu, W. D.

    2018-05-01

    An effective and reliable damage identification method for plates with a continuously scanning laser Doppler vibrometer (CSLDV) system is proposed. A new constant-speed scan algorithm is proposed to create a two-dimensional (2D) scan trajectory and automatically scan a whole plate surface. Full-field measurement of the plate can be achieved by applying the algorithm to the CSLDV system. Based on the new scan algorithm, the demodulation method is extended from one dimension for beams to two dimensions for plates to obtain a full-field operating deflection shape (ODS) of the plate from velocity response measured by the CSLDV system. The full-field ODS of an associated undamaged plate is obtained by using polynomials with proper orders to fit the corresponding full-field ODS from the demodulation method. A curvature damage index (CDI) using differences between curvatures of ODSs (CODSs) associated with ODSs that are obtained by the demodulation method and the polynomial fit is proposed to identify damage. An auxiliary CDI obtained by averaging CDIs at different excitation frequencies is defined to further assist damage identification. An experiment of an aluminum plate with damage in the form of 10.5% thickness reduction in a damage area of 0.86% of the whole scan area is conducted to investigate the proposed method. Six frequencies close to natural frequencies of the plate and one randomly selected frequency are used as sinusoidal excitation frequencies. Two 2D scan trajectories, i.e., a horizontally moving 2D scan trajectory and a vertically moving 2D scan trajectory, are used to obtain ODSs, CODSs, and CDIs of the plate. The damage is successfully identified near areas with consistently high values of CDIs at different excitation frequencies along the two 2D scan trajectories; the damage area is also identified by auxiliary CDIs.

  18. Dynamic modeling of photothermal interactions for laser-induced interstitial thermotherapy: parameter sensitivity analysis.

    PubMed

    Jiang, S C; Zhang, X X

    2005-12-01

    A two-dimensional model was developed to model the effects of dynamic changes in the physical properties on tissue temperature and damage to simulate laser-induced interstitial thermotherapy (LITT) treatment procedures with temperature monitoring. A modified Monte Carlo method was used to simulate photon transport in the tissue in the non-uniform optical property field with the finite volume method used to solve the Pennes bioheat equation to calculate the temperature distribution and the Arrhenius equation used to predict the thermal damage extent. The laser light transport and the heat transfer as well as the damage accumulation were calculated iteratively at each time step. The influences of different laser sources, different applicator sizes, and different irradiation modes on the final damage volume were analyzed to optimize the LITT treatment. The numerical results showed that damage volume was the smallest for the 1,064-nm laser, with much larger, similar damage volumes for the 980- and 850-nm lasers at normal blood perfusion rates. The damage volume was the largest for the 1,064-nm laser with significantly smaller, similar damage volumes for the 980- and 850-nm lasers with temporally interrupted blood perfusion. The numerical results also showed that the variations in applicator sizes, laser powers, heating durations and temperature monitoring ranges significantly affected the shapes and sizes of the thermal damage zones. The shapes and sizes of the thermal damage zones can be optimized by selecting different applicator sizes, laser powers, heating duration times, temperature monitoring ranges, etc.

  19. IMPAIRED VERBAL COMPREHENSION OF QUANTIFIERS IN CORTICOBASAL SYNDROME

    PubMed Central

    Troiani, Vanessa; Clark, Robin; Grossman, Murray

    2011-01-01

    Objective Patients with Corticobasal Syndrome (CBS) have atrophy in posterior parietal cortex. This region of atrophy has been previously linked with their quantifier comprehension difficulty, but previous studies used visual stimuli, making it difficult to account for potential visuospatial deficits in CBS patients. The current study evaluated comprehension of generalized quantifiers using strictly verbal materials. Method CBS patients, a brain-damaged control group (consisting of Alzheimer's Disease and frontotemporal dementia), and age-matched controls participated in this study. We assessed familiar temporal, spatial, and monetary domains of verbal knowledge comparatively. Judgment accuracy was only evaluated in statements for which patients demonstrated accurate factual knowledge about the target domain. Results We found that patients with CBS are significantly impaired in their ability to evaluate quantifiers compared to healthy seniors and a brain-damaged control group, even in this strictly visual task. This impairment was seen in the vast majority of individual CBS patients. Conclusions These findings offer additional evidence of quantifier impairment in CBS patients and emphasize that this impairment cannot be attributed to potential spatial processing impairments in patients with parietal disease. PMID:21381823

  20. Nonlinear ultrasonic stimulated thermography for damage assessment in isotropic fatigued structures

    NASA Astrophysics Data System (ADS)

    Fierro, Gian Piero Malfense; Calla', Danielle; Ginzburg, Dmitri; Ciampa, Francesco; Meo, Michele

    2017-09-01

    Traditional non-destructive evaluation (NDE) and structural health monitoring (SHM) systems are used to analyse that a structure is free of any harmful damage. However, these techniques still lack sensitivity to detect the presence of material micro-flaws in the form of fatigue damage and often require time-consuming procedures and expensive equipment. This research work presents a novel "nonlinear ultrasonic stimulated thermography" (NUST) method able to overcome some of the limitations of traditional linear ultrasonic/thermography NDE-SHM systems and to provide a reliable, rapid and cost effective estimation of fatigue damage in isotropic materials. Such a hybrid imaging approach combines the high sensitivity of nonlinear acoustic/ultrasonic techniques to detect micro-damage, with local defect frequency selection and infrared imaging. When exciting structures with an optimised frequency, nonlinear elastic waves are observed and higher frictional work at the fatigue damaged area is generated due to clapping and rubbing of the crack faces. This results in heat at cracked location that can be measured using an infrared camera. A Laser Vibrometer (LV) was used to evaluate the extent that individual frequency components contribute to the heating of the damage region by quantifying the out-of-plane velocity associated with the fundamental and second order harmonic responses. It was experimentally demonstrated the relationship between a nonlinear ultrasound parameter (βratio) of the material nonlinear response to the actual temperature rises near the crack. These results demonstrated that heat generation at damaged regions could be amplified by exciting at frequencies that provide nonlinear responses, thus improving the imaging of material damage and the reliability of NUST in a quick and reproducible manner.

  1. High-speed scanning ablation of dental hard tissues with a λ=9.3-μm CO2 laser: heat accumulation and peripheral thermal damage

    NASA Astrophysics Data System (ADS)

    Nguyen, Daniel; Staninec, Michal; Lee, Chulsung; Fried, Daniel

    2010-02-01

    A mechanically scanned CO2 laser operated at high laser pulse repetition rates can be used to rapidly and precisely remove dental decay. This study aims to determine whether these laser systems can safely ablate enamel and dentin without excessive heat accumulation and peripheral thermal damage. Peripheral thermal damage can adversely impact the mechanical strength of the irradiated tissue, particularly for dentin, and reduce the adhesion characteristics of the modified surfaces. Samples were derived from noncarious extracted molars. Pulpal temperatures were recorded using microthermocouples situated at the pulp chamber roof of samples (n=12), which were occlusally ablated using a rapid-scanning, water-cooled 300 Hz CO2 laser over a two minute time course. The mechanical strength of facially ablated dentin (n=10) was determined via four-point bend test and compared to control samples (n=10) prepared with 320 grit wet sand paper to simulate conventional preparations. Composite-to-enamel bond strength was measured via single-plane shear test for ablated/non-etched (n=10) and ablated/acid-etched (n=8) samples and compared to control samples (n=9) prepared by 320 grit wet sanding. Thermocouple measurements indicated that the temperature remained below ambient temperature at 19.0°C (s.d.=0.9) if water-cooling was used. There was no discoloration of either dentin and enamel, the treated surfaces were uniformly ablated and there were no cracks observable on the laser treated surfaces. Fourpoint bend tests yielded mean mechanical strengths of 18.2 N (s.d.=4.6) for ablated dentin and 18.1 N (s.d.=2.7) for control (p>0.05). Shear tests yielded mean bond strengths of 31.2 MPa (s.d.=2.5, p<0.01) for ablated/acid-etched samples, 5.2 MPa (s.d.=2.4, p<0.001) for ablated/non-etched samples, and 37.0 MPa (s.d.=3.6) for control. The results indicate that a rapid-scanning 300 Hz CO2 laser can effectively ablate dentin and enamel without excessive heat accumulation and with minimal

  2. Ultrafast Passive Shields for Laser and Ballistic Protection

    DTIC Science & Technology

    1991-07-15

    chemically polymerized P(DPA)) as a binder, and these were tested for ablation (i.e. laser damage threshold ) limits. Table IV below summarizes these results...50, 100, 250 and 500 AJ/pulse o 1.G, 2.5, 5.0 mJ/pulse. The following energies were used for the preliminary laser damage threshold tests: o 2.5, 5.0...these were tested for ablation (i.e. laser damage threshold ) limits. Table VI summarizes these results which are all for tests in the absence of an iris

  3. Subthreshold and micropulse diode laser photocoagulation.

    PubMed

    Dorin, Giorgio

    2003-09-01

    Retinal laser photocoagulation is a proven, effective treatment for various retinal disorders. Common clinical protocols use intra-operatively visible endpoints that cause iatrogenic chorioretinal damage. For this reason, laser therapy is normally limited to levels of disease severity for which the benefit-to-risk ratio justifies its application. The use of 810 nm diode lasers in the MicroPulse mode offers the surgeon the possibility to minimize iatrogenic retinal damage. A less destructive laser therapy with a more favorable benefit-to-risk ratio could justify treatment earlier in the course of the disease, allowing for stabilization or improvement of less compromised visual functions.

  4. Method for producing damage resistant optics

    DOEpatents

    Hackel, Lloyd A.; Burnham, Alan K.; Penetrante, Bernardino M.; Brusasco, Raymond M.; Wegner, Paul J.; Hrubesh, Lawrence W.; Kozlowski, Mark R.; Feit, Michael D.

    2003-01-01

    The present invention provides a system that mitigates the growth of surface damage in an optic. Damage to the optic is minimally initiated. In an embodiment of the invention, damage sites in the optic are initiated, located, and then treated to stop the growth of the damage sites. The step of initiating damage sites in the optic includes a scan of the optic using a laser to initiate defects. The exact positions of the initiated sites are identified. A mitigation process is performed that locally or globally removes the cause of subsequent growth of the damaged sites.

  5. Effect of doping of KDP crystal with amino acid L-arginine on the strength properties and character of laser damage

    NASA Astrophysics Data System (ADS)

    Dolzhenkova, E. F.; Kostenyukova, E. I.; Bezkrovnaya, O. N.; Pritula, I. M.

    2017-11-01

    Studied were the strength characteristics of KDP crystals doped with L-arginine under a concentrated load and irradiation of the first harmonic YAG:Nd3+ laser. The crystals were obtained by means of the temperature reduction method on a point seed, the content of L-arginine in the aqueous solution being 0.3, 0.4, 1.0 and 1.4 wt%. The character of the dependence of KDP microhardness versus the concentration of amino acid in the crystal was investigated. The regularities of brittle damage of the doped KDP crystal at mechanical testing and laser irradiation were shown to be similar. As confirmed in the study, the planes of easy crack extension in the crystal are {2 2 1}, (1 0 0), and (0 0 1) planes, the cracks mainly propagate parallel to {2 2 1} planes. The mechanical and laser strength values of doped KDP crystals were evaluated.

  6. Histologic evaluation of laser lipolysis comparing continuous wave vs pulsed lasers in an in vivo pig model.

    PubMed

    Levi, Jessica R; Veerappan, Anna; Chen, Bo; Mirkov, Mirko; Sierra, Ray; Spiegel, Jeffrey H

    2011-01-01

    To evaluate acute and delayed laser effects of subdermal lipolysis and collagen deposition using an in vivo pig model and to compare histologic findings in fatty tissue after continuous wave diode (CW) vs pulsed laser treatment. Three CW lasers (980, 1370, and 1470 nm) and 3 pulsed lasers (1064, 1320, and 1440 nm) were used to treat 4 Göttingen minipigs. Following administration of Klein tumescent solution, a laser cannula was inserted at the top of a 10 × 2.5-cm rectangle and was passed subdermally to create separate laser "tunnels." Temperatures at the surface and at intervals of 4-mm to 20-mm depths were recorded immediately after exposure and were correlated with skin injury. Full-thickness cutaneous biopsy specimens were obtained at 1 day, 1 week, and 1 month after exposure and were stained with hematoxylin-eosin and trichrome stain. Qualitative and semiquantitative histopathologic evaluations were performed with attention to vascular damage, lipolysis, and collagen deposition. Skin surface damage occurred at temperatures exceeding 46°C. Histologic examination at 1 day after exposure showed hemorrhage, fibrous collagen fiber coagulation, and adipocyte damage. Adipocytes surrounded by histiocytes, a marker of lipolysis, were present at 1 week and 1 month after exposure. Collagen deposition in subdermal fatty tissue and in reticular dermis of some specimens was noted at 1 week and had increased at 1 month. Tissue treated with CW laser at 1470 nm demonstrated greater hemorrhage and more histiocytes at damage sites than tissue treated with pulsed laser at 1440 nm. There was a trend toward more collagen deposition with pulsed lasers than with CW lasers, but this was not statistically significant. Histopathologic comparison between results of CW laser at 980 nm vs pulsed laser at 1064 nm showed the same trend. Hemorrhage differences may result from pulse duration variations. A theoretical calculation estimating temperature rise in vessels supported this

  7. Repair of a Mirror Coating on a Large Optic for High Laser Damage Applications using Ion Milling and Over-Coating Methods.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Field, Ella Suzanne; Bellum, John Curtis; Kletecka, Damon E.

    When an optical coating is damaged, deposited incorrectly, or is otherwise unsuitable, the conventional method to restore the optic often entails repolishing the optic surface, which can incur a large cost and long lead time. We propose three alternative options to repolishing, including (i) burying the unsuitable coating under another optical coating, (ii) using ion milling to etch the unsuitable coating completely from the optic surface, and then recoating the optic, and (iii) using ion milling to etch through a number of unsuitable layers, leaving the rest of the coating intact, and then recoating the layers that were etched. Repairsmore » were made on test optics with dielectric mirror coatings according to the above three options. The mirror coatings to be repaired were quarter wave stacks of HfO 2 and SiO 2 layers for high reflection at 1054 nm at 45° incidence in P-polarization. One of the coating layers was purposely deposited incorrectly as Hf metal instead of HfO 2 to evaluate the ability of each repair method to restore the coating’s high laser-induced damage threshold (LIDT) of 64.0 J/cm 2. Finally, the repaired coating with the highest resistance to laser-induced damage was achieved using repair method (ii) with an LIDT of 49.0 – 61.0 J/cm 2.« less

  8. Repair of a mirror coating on a large optic for high laser damage applications using ion milling and over-coating methods

    NASA Astrophysics Data System (ADS)

    Field, Ella S.; Bellum, John C.; Kletecka, Damon E.

    2017-01-01

    When an optical coating is damaged, deposited incorrectly, or is otherwise unsuitable, the conventional method to restore the optic often entails repolishing the optic surface, which can incur a large cost and long lead time. We propose three alternative options to repolishing, including (i) burying the unsuitable coating under another optical coating, (ii) using ion milling to etch the unsuitable coating completely from the optic surface and then recoating the optic, and (iii) using ion milling to etch through a number of unsuitable layers, leaving the rest of the coating intact, and then recoating the layers that were etched. Repairs were made on test optics with dielectric mirror coatings according to the above three options. The mirror coatings to be repaired were quarter wave stacks of HfO2 and SiO2 layers for high reflection at 1054 nm at 45 deg incidence in P-polarization. One of the coating layers was purposely deposited incorrectly as Hf metal instead of HfO2 to evaluate the ability of each repair method to restore the coating's high laser-induced damage threshold (LIDT) of 64.0 J/cm2. The repaired coating with the highest resistance to laser-induced damage was achieved using repair method (ii) with an LIDT of 49.0 to 61.0 J/cm2.

  9. Repair of a mirror coating on a large optic for high laser damage applications using ion milling and over-coating methods

    DOE PAGES

    Field, Ella S.; Bellum, John C.; Kletecka, Damon E.

    2016-07-08

    Here, when an optical coating is damaged, deposited incorrectly, or is otherwise unsuitable, the conventional method to restore the optic often entails repolishing the optic surface, which can incur a large cost and long lead time. We propose three alternative options to repolishing, including (i) burying the unsuitable coating under another optical coating, (ii) using ion milling to etch the unsuitable coating completely from the optic surface and then recoating the optic, and (iii) using ion milling to etch through a number of unsuitable layers, leaving the rest of the coating intact, and then recoating the layers that were etched.more » Repairs were made on test optics with dielectric mirror coatings according to the above three options. The mirror coatings to be repaired were quarter wave stacks of HfO 2 and SiO 2 layers for high reflection at 1054 nm at 45 deg incidence in P-polarization. One of the coating layers was purposely deposited incorrectly as Hf metal instead of HfO2 to evaluate the ability of each repair method to restore the coating’s high laser-induced damage threshold (LIDT) of 64.0 J/cm 2. The repaired coating with the highest resistance to laser-induced damage was achieved using repair method (ii) with an LIDT of 49.0 to 61.0 J/cm 2.« less

  10. Repair of a Mirror Coating on a Large Optic for High Laser Damage Applications using Ion Milling and Over-Coating Methods.

    DOE PAGES

    Field, Ella Suzanne; Bellum, John Curtis; Kletecka, Damon E.

    2016-06-01

    When an optical coating is damaged, deposited incorrectly, or is otherwise unsuitable, the conventional method to restore the optic often entails repolishing the optic surface, which can incur a large cost and long lead time. We propose three alternative options to repolishing, including (i) burying the unsuitable coating under another optical coating, (ii) using ion milling to etch the unsuitable coating completely from the optic surface, and then recoating the optic, and (iii) using ion milling to etch through a number of unsuitable layers, leaving the rest of the coating intact, and then recoating the layers that were etched. Repairsmore » were made on test optics with dielectric mirror coatings according to the above three options. The mirror coatings to be repaired were quarter wave stacks of HfO 2 and SiO 2 layers for high reflection at 1054 nm at 45° incidence in P-polarization. One of the coating layers was purposely deposited incorrectly as Hf metal instead of HfO 2 to evaluate the ability of each repair method to restore the coating’s high laser-induced damage threshold (LIDT) of 64.0 J/cm 2. Finally, the repaired coating with the highest resistance to laser-induced damage was achieved using repair method (ii) with an LIDT of 49.0 – 61.0 J/cm 2.« less

  11. Repair of a mirror coating on a large optic for high laser damage applications using ion milling and over-coating methods

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Field, Ella S.; Bellum, John C.; Kletecka, Damon E.

    Here, when an optical coating is damaged, deposited incorrectly, or is otherwise unsuitable, the conventional method to restore the optic often entails repolishing the optic surface, which can incur a large cost and long lead time. We propose three alternative options to repolishing, including (i) burying the unsuitable coating under another optical coating, (ii) using ion milling to etch the unsuitable coating completely from the optic surface and then recoating the optic, and (iii) using ion milling to etch through a number of unsuitable layers, leaving the rest of the coating intact, and then recoating the layers that were etched.more » Repairs were made on test optics with dielectric mirror coatings according to the above three options. The mirror coatings to be repaired were quarter wave stacks of HfO 2 and SiO 2 layers for high reflection at 1054 nm at 45 deg incidence in P-polarization. One of the coating layers was purposely deposited incorrectly as Hf metal instead of HfO2 to evaluate the ability of each repair method to restore the coating’s high laser-induced damage threshold (LIDT) of 64.0 J/cm 2. The repaired coating with the highest resistance to laser-induced damage was achieved using repair method (ii) with an LIDT of 49.0 to 61.0 J/cm 2.« less

  12. CONFOCAL MICROSCOPY SYSTEM PERFORMANCE: LASER POWER MEASUREMENTS

    EPA Science Inventory

    Laser power abstract
    The reliability of the confocal laser-scanning microscope (CLSM) to obtain intensity measurements and quantify fluorescence data is dependent on using a correctly aligned machine that contains a stable laser power. The laser power test appears to be one ...

  13. Laser beam shaping for studying thermally induced damage

    NASA Astrophysics Data System (ADS)

    Masina, Bathusile N.; Bodkin, Richard; Mwakikunga, Bonex; Forbes, Andrew

    2011-10-01

    This paper presents an implementation of a laser beam shaping system for both heating a diamond tool and measuring the resulting temperature optically. The influence the initial laser parameters have on the resultant temperature profiles is shown experimentally and theoretically. A CO2 laser beam was used as the source to raise the temperature of the diamond tool and the resultant temperature was measured by using the blackbody principle. We have successfully transformed a Gaussian beam profile into a flat-top beam profile by using a diffractive optical element as a phase element in conjunction with a Fourier transforming lens. In this paper, we have successfully demonstrated temperature profiles across the diamond tool surface using two laser beam profiles and two optical setups, thus allowing a study of temperature influences with and without thermal stress. The generation of such temperature profiles on the diamond tool in the laboratory is important in the study of changes that occur in diamond tools, particularly the reduced efficiency of such tools in applications where extreme heating due to friction is expected.

  14. Lasers | RadTown USA | US EPA

    EPA Pesticide Factsheets

    2018-05-01

    Laser light is an intense, focused beam of visible light radiation. Lasers are used in many workplaces, including construction, surveying and medicine. High-powered laser light can cause severe skin burns and permanent eye damage.

  15. Methods for improving the damage performance of fused silica polished by magnetorheological finishing

    DOE PAGES

    Kafka, Kyle R. P.; Hoffman, Brittany N.; Papernov, Semyon; ...

    2017-12-11

    The laser-induced damage threshold of fused-silica samples processed via magnetorheological finishing is investigated for polishing compounds depending on the type of abrasive material and the post-polishing surface roughness. The effectiveness of laser conditioning is examined using a ramped pre-exposure with the same 351-nm, 3-ns Gaussian pulses. Lastly, we examine chemical etching of the surface and correlate the resulting damage threshold to the etching protocol. A combination of etching and laser conditioning is found to improve the damage threshold by a factor of ~3, while maintaining <1-nm surface roughness.

  16. Methods for improving the damage performance of fused silica polished by magnetorheological finishing

    NASA Astrophysics Data System (ADS)

    Kafka, K. R. P.; Hoffman, B.; Papernov, S.; DeMarco, M. A.; Hall, C.; Marshall, K. L.; Demos, S. G.

    2017-12-01

    The laser-induced damage threshold of fused-silica samples processed via magnetorheological finishing is investigated for polishing compounds depending on the type of abrasive material and the post-polishing surface roughness. The effectiveness of laser conditioning is examined using a ramped pre-exposure with the same 351-nm, 3-ns Gaussian pulses. Finally, we examine chemical etching of the surface and correlate the resulting damage threshold to the etching protocol. A combination of etching and laser conditioning is found to improve the damage threshold by a factor of 3, while maintaining <1-nm surface roughness.

  17. Damage identification of beam structures using free response shapes obtained by use of a continuously scanning laser Doppler vibrometer system

    NASA Astrophysics Data System (ADS)

    Xu, Y. F.; Chen, Da-Ming; Zhu, W. D.

    2017-08-01

    Spatially dense operating deflection shapes and mode shapes can be rapidly obtained by use of a continuously scanning laser Doppler vibrometer (CSLDV) system, which sweeps its laser spot over a vibrating structure surface. This paper introduces a new type of vibration shapes called a free response shape (FRS) that can be obtained by use of a CSLDV system, and a new damage identification methodology using FRSs is developed for beam structures. An analytical expression of FRSs of a damped beam structure is derived, and FRSs from the analytical expression compare well with those from a finite element model. In the damage identification methodology, a free-response damage index (FRDI) is proposed, and damage regions can be identified near neighborhoods with consistently high values of FRDIs associated with different modes; an auxiliary FRDI is defined to assist identification of the neighborhoods. A FRDI associated with a mode consists of differences between curvatures of FRSs associated with the mode in a number of half-scan periods of a CSLDV system and those from polynomials that fit the FRSs with properly determined orders. A convergence index is proposed to determine the proper order of a polynomial fit. One advantage of the methodology is that the FRDI does not require any baseline information of an undamaged beam structure, if it is geometrically smooth and made of materials that have no stiffness and mass discontinuities. Another advantage is that FRDIs associated with multiple modes can be obtained using free response of a beam structure measured by a CSLDV system in one scan. The number of half-scan periods for calculation of the FRDI associated with a mode can be determined by use of the short-time Fourier transform. The proposed methodology was numerically and experimentally applied to identify damage in beam structures; effects of the scan frequency of a CSLDV system on qualities of obtained FRSs were experimentally investigated.

  18. Physical mechanisms of SiN{sub x} layer structuring with ultrafast lasers by direct and confined laser ablation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rapp, S., E-mail: rapp@hm.edu; Erlangen Graduate School in Advanced Optical Technologies; Heinrich, G.

    2015-03-14

    In the production process of silicon microelectronic devices and high efficiency silicon solar cells, local contact openings in thin dielectric layers are required. Instead of photolithography, these openings can be selectively structured with ultra-short laser pulses by confined laser ablation in a fast and efficient lift off production step. Thereby, the ultrafast laser pulse is transmitted by the dielectric layer and absorbed at the substrate surface leading to a selective layer removal in the nanosecond time domain. Thermal damage in the substrate due to absorption is an unwanted side effect. The aim of this work is to obtain a deepermore » understanding of the physical laser-material interaction with the goal of finding a damage-free ablation mechanism. For this, thin silicon nitride (SiN{sub x}) layers on planar silicon (Si) wafers are processed with infrared fs-laser pulses. Two ablation types can be distinguished: The known confined ablation at fluences below 300 mJ/cm{sup 2} and a combined partial confined and partial direct ablation at higher fluences. The partial direct ablation process is caused by nonlinear absorption in the SiN{sub x} layer in the center of the applied Gaussian shaped laser pulses. Pump-probe investigations of the central area show ultra-fast reflectivity changes typical for direct laser ablation. Transmission electron microscopy results demonstrate that the Si surface under the remaining SiN{sub x} island is not damaged by the laser ablation process. At optimized process parameters, the method of direct laser ablation could be a good candidate for damage-free selective structuring of dielectric layers on absorbing substrates.« less

  19. Laser debonding of ceramic brackets: a comprehensive review.

    PubMed

    Azzeh, Ezz; Feldon, Paul J

    2003-01-01

    Since the invention of the ruby laser in the early 1960s, tremendous advances have been made in optic laser technology. Orthodontists have found various uses for lasers, including the debonding of ceramic brackets. Laser energy degrades the adhesive resin used to bond brackets. Consequently, lower forces can be used than when mechanical debonding is performed, reducing the risk of enamel damage. However, the heat produced by some lasers can damage the tooth pulp. Selecting the appropriate laser, resin, and bracket combination can minimize risks and make debonding more efficient. The purpose of this article is to give the clinician an up-to-date, comprehensive literature review about the clinical characteristics of debonding ceramic brackets with lasers.

  20. Laser Crystal

    NASA Technical Reports Server (NTRS)

    1998-01-01

    Lightning Optical Corporation, under an SBIR (Small Business Innovative Research) agreement with Langley Research Center, manufactures oxide and fluoride laser gain crystals, as well as various nonlinear materials. The ultimate result of this research program is the commercial availability in the marketplace of a reliable source of high-quality, damage resistant laser material, primarily for diode-pumping applications.

  1. High Cycle Fatigue Performance in Laser Shock Peened TC4 Titanium Alloys Subjected to Foreign Object Damage

    NASA Astrophysics Data System (ADS)

    Luo, Sihai; Nie, Xiangfan; Zhou, Liucheng; Li, Yiming; He, Weifeng

    2018-03-01

    During their service, titanium alloys are likely to suffer from the foreign object damage (FOD), resulting in a decrease in their fatigue strength. Laser shock peening (LSP) has been proved to effectively increase the damage tolerance of military engine components by introducing a magnitude compressive residual stress in the near-surface layer of alloys. In this paper, smooth specimens of a TC4 titanium alloy were used and treated by LSP and subsequently exposed to FOD, which was simulated by firing a steel sphere with a nominal velocity of 300 m/s, at 90° with the leading edge of the LSP-treated region using a light gas gun. All impacted specimens were then subjected to fatigue loading. The results showed that LSP could effectively improve the fatigue strength of the damaged specimens. The effect of LSP on the fatigue strength was assessed through fracture observations, microhardness tests and residual stress analyses. The residual stresses due to the plastic deformation caused by LSP and the FOD impact, which were found to play a crucial role on the fatigue strength, were determined using the commercial software ABAQUS.

  2. Development of a shock wave adhesion test for composite bonds by pulsed laser and mechanical impacts

    NASA Astrophysics Data System (ADS)

    Ecault, R.; Boustie, M.; Touchard, F.; Arrigoni, M.; Berthe, L.

    2014-05-01

    Evaluating the bonding quality of composite material is becoming one of the main challenges faced by aeronautic industries. This work aims to the development of a technique using shock wave, which would enable to quantify the bonding mechanical quality. Laser shock experiments were carried out. This technique enables high tensile stress generation in the thickness of composite bonds. The resulting damage has been quantified using different methods such as confocal microscopy, ultrasound and cross section observation. The discrimination between a correct bond and a weak bond was possible thanks to these experiments. Nevertheless, laser sources are not well adapted for optimization of such a test because of often fixed settings. That is why mechanical impacts on bonded composites were also performed in this work. By changing the thickness of aluminum projectiles, the generated tensile stresses by the shock wave propagation were moved toward the composite/bond interface. The made observations prove that the technique optimization is possible. The key parameters for the development of a bonding test using shock waves have been identified.

  3. Development of a shock wave adhesion test for composite bonds by laser pulsed and mechanical impacts

    NASA Astrophysics Data System (ADS)

    Ecault, Romain; Boustie, Michel; Touchard, Fabienne; Arrigoni, Michel; Berthe, Laurent; CNRS Collaboration

    2013-06-01

    Evaluating the bonding quality of composite material is becoming one of the main challenges faced by aeronautic industries. This work aims the development of a technique using shock wave, which would enable to quantify the bonding mechanical quality. Laser shock experiments were carried out. This technique enables high tensile stress generation in the thickness of composite bond without any mechanical contact. The resulting damage has been quantified using different method such as confocal microscopy, ultrasound and cross section observation. The discrimination between a correct bond and a weak bond was possible thanks to these experiments. Nevertheless, laser sources are not well adapted for optimization of such a test since it has often fixed parameters. That is why mechanical impacts bonded composites were also performed in this work. By changing the thickness of aluminum projectiles, the tensile stresses generated by the shock wave propagation were moved toward the composite/bond interface. The observations made prove that the optimization of the technique is possible. The key parameters for the development of a bonding test using shock wave have been identified.

  4. Micropulsed diode laser therapy: evolution and clinical applications.

    PubMed

    Sivaprasad, Sobha; Elagouz, Mohammed; McHugh, Dominic; Shona, Olajumoke; Dorin, Giorgio

    2010-01-01

    Many clinical trials have demonstrated the clinical efficacy of laser photocoagulation in the treatment of retinal vascular diseases, including diabetic retinopathy. There is, however, collateral iatrogenic retinal damage and functional loss after conventional laser treatment. Such side effects may occur even when the treatment is appropriately performed because of morphological damage caused by the visible endpoint, typically a whitening burn. The development of the diode laser with micropulsed emission has allowed subthreshold therapy without a visible burn endpoint. This greatly reduces the risk of structural and functional retinal damage, while retaining the therapeutic efficacy of conventional laser treatment. Studies using subthreshold micropulse laser protocols have reported successful outcomes for diabetic macular edema, central serous chorioretinopathy, macular edema secondary to retinal vein occlusion, and primary open angle glaucoma. The report includes the rationale and basic principles underlying micropulse diode laser therapy, together with a review of its current clinical applications. Copyright © 2010 Elsevier Inc. All rights reserved.

  5. Investigation of possible fs-LASIK induced retinal damage

    NASA Astrophysics Data System (ADS)

    Schumacher, S.; Sander, M.; Stolte, A.; Doepke, C.; Baumgaertner, W.; Lubatschowski, H.

    2006-02-01

    Rapid development of new laser technologies enabled the application of ultra short lasers in refractive surgery. Focused ultra short laser pulses in near-infrared spectral range can generate a laser induced breakdown (LIB) in the cornea, which will disrupt the tissue. Cutting depth and position can be established by varying the laser focus. The fs-LASIK technique allows both flap and lenticule to be formed by using fs-pulses without the presence of any mechanical impact. During the cutting process not all of the pulse energy is deposited into the cornea; approximately half of the remaining energy propagates through the eye and reaches the retina. Though defocused, the transmitted energy can still induce damage to the retina due to absorption by the retinal pigment epithelium and the transfer of thermal energy to surrounding tissue. The fs-LASIK process was simulated with two laser systems; one continous-wave and one in the fs-regime. For the simulation the exposure time and focusing numerical aperature which defines the retinal spot size were varied. The Damage thresholds of the laser beam exposed eyes were determined in terms of ophthalmoscopic and histopathologic observations.

  6. 3-ω damage threshold evaluation of final optics components using Beamlet Mule and off-line testing

    NASA Astrophysics Data System (ADS)

    Kozlowski, Mark R.; Maricle, Stephen M.; Mouser, Ron P.; Schwartz, Sheldon; Wegner, Paul J.; Weiland, Timothy L.

    1999-07-01

    A statistics-based model is being develop to predict the laser-damage-limited lifetime of UV optical components on the NIF laser. In order to provide data for the mode, laser damage experiments were performed on the Beamlet laser system at LLNL. An early protoype NIF focus lens was exposed to twenty 351 nm pulses at an average fluence of 5 J/cm2, 3ns. Using a high resolution optic inspection inspection system a total of 353 damage sites was detected within the 1160 cm2 beam aperture. Through inspections of the lens before, after and, in some cases, during the campaign, pulse to pulse damage growth rates were measured for damage initiating both on the surface and at bulk inclusions. Growth rates as high as 79 micrometers /pulse were observed for damage initiating at pre-existing scratches in the surface. For most damage sites on the optic, both on the surface and at bulk inclusions. Growth rates as high as 79 micrometers /pulse were observed for damage initiating at per- existing scratches in the surface. For most damage sites on the optic, both surface and bulk, the damage growth rate was approximately 10(Mu) m/pulse.

  7. Space Qualification of Laser Diode Arrays

    NASA Technical Reports Server (NTRS)

    Troupaki, Elisavet; Kashem, Nasir B.; Allan, Graham R.; Vasilyev, Aleksey; Stephen, Mark

    2005-01-01

    Laser instruments have great potential in enabling a new generation of remote-sensing scientific instruments. NASA s desire to employ laser instruments aboard satellites, imposes stringent reliability requirements under severe conditions. As a result of these requirements, NASA has a research program to understand, quantify and reduce the risk of failure to these instruments when deployed on satellites. Most of NASA s proposed laser missions have base-lined diode-pumped Nd:YAG lasers that generally use quasi-constant wave (QCW), 808 nm Laser Diode Arrays (LDAs). Our group has an on-going test program to measure the performance of these LDAs when operated in conditions replicating launch and orbit. In this paper, we report on the results of tests designed to measure the effect of vibration loads simulating launch into space and the radiation environment encountered on orbit. Our primary objective is to quantify the performance of the LDAs in conditions replicating those of a satellite instrument, determine their limitations and strengths which will enable better and more robust designs. To this end we have developed a systematic testing strategy to quantify the effect of environmental stresses on the optical and electrical properties of the LDA.

  8. Photobiomodulation in laser surgery

    NASA Astrophysics Data System (ADS)

    Liu, Timon Cheng-Yi; Rong, Dong-Liang; Huang, Jin; Deng, Xiao-Yuan; Liu, Song-Hao

    2006-01-01

    Laser surgery provides good exposure with clear operating fields and satisfactory preliminary functional results. In contrast to conventional excision, it was found that matrix metalloproteinases and the tissue inhibitors of metalloproteinases -1 mRNA expression is higher, myofibroblasts appeared and disappeared slower in laser excision wounds. It has been suggested that the better anatomical and functional results achieved following laser cordectomy may be explained by the fact that such procedures result in better, more rapid healing processes to recover vocal cord for early glottic tumors and better. In this paper, the role of photobiomodulation in laser surgery will be discussed by the cultured monolayer normal human skin fibroblast model of the photobiomodulation of marginal irradiation of high intensity laser beam, the photobiomodulation related to the irradiated tissue, the biological information model of photobiomodulation and the animal models of laser surgery. Although high intensity laser beam is so intense that it destroys the irradiated cells or tissue, its marginal irradiation intensity is so low that there is photobiomodulation on non-damage cells to modulate the regeneration of partly damaged tissue so that the surgery of laser of different parameters results in different post-surgical recovery. It was concluded that photobiomodulation might play an important role in the long-term effects of laser surgery, which might be used to design laser surgery.

  9. Optical cell cleaning with NIR femtosecond laser pulses

    NASA Astrophysics Data System (ADS)

    Uchugonova, Aisada; Breunig, Hans Georg; Batista, Ana; König, Karsten

    2015-03-01

    Femtosecond laser microscopes have been used as both micro and nanosurgery tools. The optical knock-out of undesired cells in multiplex cell clusters shall be further reported on in this study. Femtosecond laser-induced cell death is beneficial due to the reduced collateral side effects and therefore can be used to selectively destroy target cells within monolayers, as well as within 3D tissues, all the while preserving cells of interest. This is an important characteristic for the application in stem cell research and cancer treatment. Non-precise damage compromises the viability of neighboring cells by inducing side effects such as stress to the cells surrounding the target due to the changes in the microenvironment, resulting from both the laser and laser-exposed cells. In this study, optimum laser parameters for optical cleaning by isolating single cells and cell colonies are exploited through the use of automated software control. Physiological equilibrium and cellular responses to the laser induced damages are also investigated. Cell death dependence on laser focus, determination and selectivity of intensity/dosage, controllable damage and cell recovery mechanisms are discussed.

  10. Damage thresholds for blaze diffraction gratings and grazing incidence optics at an X-ray free-electron laser

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Krzywinski, Jacek; Conley, Raymond; Moeller, Stefan

    The Linac Coherent Light Source is upgrading its machine to high repetition rate and to extended ranges. Novel coatings, with limited surface oxidation, which are able to work at the carbon edge, are required. In addition, high-resolution soft X-ray monochromators become necessary. One of the big challenges is to design the mirror geometry and the grating profile to have high reflectivity (or efficiency) and at the same time survive the high peak energy of the free-electron laser pulses. For these reasons the experimental damage threshold, at 900 eV, of two platinum-coated gratings with different blazed angles has been investigated. The gratingsmore » were tested at 1° grazing incidence. To validate a model for which the damage threshold on the blaze grating can be estimated by calculating the damage threshold of a mirror with an angle of incidence identical to the angle of incidence on the grating plus the blaze angle, tests on Pt-coated substrates have also been performed. The results confirmed the prediction. Uncoated silicon, platinum and SiB 3 (both deposited on a silicon substrate) were also investigated. In general, the measured damage threshold at grazing incidence is higher than that calculated under the assumption that there is no energy transport from the volume where the photons are absorbed. However, it was found that, for the case of the SiB 3 coating, the grazing incidence condition did not increase the damage threshold, indicating that the energy transport away from the extinction volume is negligible.« less

  11. Damage thresholds for blaze diffraction gratings and grazing incidence optics at an X-ray free-electron laser

    DOE PAGES

    Krzywinski, Jacek; Conley, Raymond; Moeller, Stefan; ...

    2018-01-01

    The Linac Coherent Light Source is upgrading its machine to high repetition rate and to extended ranges. Novel coatings, with limited surface oxidation, which are able to work at the carbon edge, are required. In addition, high-resolution soft X-ray monochromators become necessary. One of the big challenges is to design the mirror geometry and the grating profile to have high reflectivity (or efficiency) and at the same time survive the high peak energy of the free-electron laser pulses. For these reasons the experimental damage threshold, at 900 eV, of two platinum-coated gratings with different blazed angles has been investigated. The gratingsmore » were tested at 1° grazing incidence. To validate a model for which the damage threshold on the blaze grating can be estimated by calculating the damage threshold of a mirror with an angle of incidence identical to the angle of incidence on the grating plus the blaze angle, tests on Pt-coated substrates have also been performed. The results confirmed the prediction. Uncoated silicon, platinum and SiB 3 (both deposited on a silicon substrate) were also investigated. In general, the measured damage threshold at grazing incidence is higher than that calculated under the assumption that there is no energy transport from the volume where the photons are absorbed. However, it was found that, for the case of the SiB 3 coating, the grazing incidence condition did not increase the damage threshold, indicating that the energy transport away from the extinction volume is negligible.« less

  12. Influence of Deposition Temperature on Optical and Laser-Induced Damage Properties of LaTiO3 Films

    NASA Astrophysics Data System (ADS)

    Su, Junhong; Xu, Junqi; Yang, Chen; Cheng, Yaojin

    2015-08-01

    LaTiO3 films were prepared at room temperature, 60, 140 and 220°C using a thermal vapor deposition technique with an electronic beam gun to investigate the relationship between deposition temperatures and the optical properties of the samples. In the ellipsometric analysis, the corresponding refractive indexes were 1.8993, 1.9123, 1.9197 and 1.9283 at a wavelength of 1064 nm. At the same time, extremely low absorption characteristics of all the samples presented in the visible and IR regions. With the same high-energy testing laser of 200 mJ (about 40 J/cm2) at a wavelength of 1064 nm and a pulse width of 10 ns, the laser-induced damage threshold (LIDT) of the LaTiO3 samples prepared at different temperatures were 15.5, 16.7, 18.5 and 18.2 J/cm2, respectively. This shows that a higher LIDT may be obtained at higher deposition temperatures.

  13. Renal denervation using focused infrared fiber lasers: a potential treatment for hypertension.

    PubMed

    Alexander, Vinay V; Shi, Zhennan; Iftekher, Fariha; Welsh, Michael J; Gurm, Hitinder S; Rising, Gail; Yanovich, Amber; Walacavage, Kim; Islam, Mohammed N

    2014-11-01

    Renal denervation has recently become of great interest as a potential treatment for resistant hypertension. Denervation techniques using radio frequency (RF) or ultrasound energy sources have already been explored in literature. In this study, we investigate the use of lasers as a potential energy source for renal denervation. In vitro studies are performed in porcine/ovine renal arteries with focused laser beams at 980 nm, 1210 nm, and 1700 nm to study the ability to damage renal nerves without causing injury to non-target tissue structures like the endothelium. Then, a 980 nm laser catheter prototype is built and used to demonstrate in vivo renal denervation in ovine renal arteries. This study utilizes fiber coupled infrared lasers at 980 nm, 1210 nm, and 1700 nm. In vitro laser denervation studies at 980 nm are performed in both porcine and ovine renal arteries to study the ability of focused laser beams to damage renal nerves without injuring the endothelium. In vitro studies using lasers close to the lipid absorption lines at 1210 nm and 1700 nm are also performed in porcine renal arteries to study the possibility of selectively damaging the renal nerves by targeting the lipid myelin sheaths surrounding the nerves. Then, a laser catheter prototype is designed and built for in vivo renal denervation in ovine renal arteries using the 980 nm laser (powers ranging from 2 to 4 W, 5 seconds per exposure). Histochemical evaluations of the frozen sections are performed using methylthiazolyldiphenyl-tetrazolium bromide (MTT) assay. Histochemical analysis of in vitro laser treatments at 980 nm in porcine and ovine renal arteries show clear evidence of laser-induced renal nerve damage without injury to the endothelium and part of the media. No evidence of selective nerve damage is observed using the 1210 nm and 1700 nm lasers with the current treatment parameters. Histochemical analysis of in vivo laser treatments in ovine renal arteries

  14. Environmental testing of a diode-laser-pumped Nd:YAG laser and a set of diode-laser-arrays

    NASA Technical Reports Server (NTRS)

    Hemmati, H.; Lesh, J. R.

    1989-01-01

    Results of the environmental test of a compact, rigid and lightweight diode-laser-pumped Nd:YAG laser module are discussed. All optical elements are bonded onto the module using space applicable epoxy, and two 200 mW diode laser arrays for pump sources are used to achieve 126 mW of CW output with about 7 percent electrical-to-optical conversion efficiency. This laser assembly and a set of 20 semiconductor diode laser arrays were environmentally tested by being subjected to vibrational and thermal conditions similar to those experienced during launch of the Space Shuttle, and both performed well. Nevertheless, some damage to the laser front facet in diode lasers was observed. Significant degradation was observed only on lasers which performed poorly in the life test. Improvements in the reliability of the Nd:YAG laser are suggested.

  15. New laser protective eyewear

    NASA Astrophysics Data System (ADS)

    McLear, Mark

    1996-04-01

    Laser technology has significantly impacted our everyday life. Lasers are now used to correct your vision, clear your arteries, and are used in the manufacturing of such diverse products as automobiles, cigarettes, and computers. Lasers are no longer a research tool looking for an application. They are now an integral part of manufacturing. In the case of Class IV lasers, this explosion in laser applications has exposed thousands of individuals to potential safety hazards including eye damage. Specific protective eyewear designed to attenuate the energy of the laser beam below the maximum permissible exposure is required for Class 3B and Class IV lasers according to laser safety standards.

  16. Selection of Optical Cavity Surface Coatings for 1micron Laser Based Missions

    NASA Technical Reports Server (NTRS)

    Hedgeland, Randy J.; Straka, Sharon; Matsumura, Mark; Hammerbacher, Joseph

    2004-01-01

    The particulate surface cleanliness level on several coatings for aluminum and beryllium substrates were examined for use in the optical cavities of high pulse energy Nd:YAG Q-switched, diode-pumped lasers for space flight applications. Because of the high intensity of the lasers, any contaminants in the laser beam path could damage optical coatings and limit the instrument mission objectives at the operating wavelength of 1 micron (micrometer). Our goal was to achieve an EST-STD-CC1246D Level 100 particulate distribution or better to ensure particulate redistribution during launch would not adversely affect the performance objectives. Tapelifts were performed to quantify the amount of particles using in-house developed procedures. The primary candidate coatings included chromate conversion coating aluminum (Al), uncoated Al electroless Nickel (Ni) on Al, Ni-gold (Au) on Al, anodized Al, and gold (Au)/Ni on Beryllium (Be). The results indicate that there were advantages in Ni and Au coating applications for the two major substrates, Al and Be, when considering applications that need to meet launch environments.

  17. Damage morphology study of high cycle fatigued as-cast Mg–3.0Nd–0.2Zn–Zr (wt.%) alloy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yue, Haiyan; Fu, Penghuai, E-mail: fph112sjtu@sjtu.edu.cn; Peng, Liming

    Laser scanning confocal microscopy (LSCM) and Electron back-scattered diffraction (EBSD) were applied to the study of surface morphology variation of as-cast Mg–3.0Nd–0.2Zn–Zr (NZ30K) (wt.%) alloy under tension-compression fatigue test at room temperature. Two kinds of typical damage morphologies were observed in fatigued NZ30K alloy: One was parallel lines on basal planes led by the cumulation of basal slips, called persistent slip markings (PSMs), and the other was lens shaped, thicker and in less density, led by the formation of twinning. The surface fatigue damage morphology evolution was analyzed in a statistical way. The influences of stress amplitude and grain orientationmore » on fatigue deformation mechanisms were discussed and the non-uniform deformation among grains and the PSMs, within twinning were described quantitatively. - Highlights: • Fatigue morphology evolution was studied by Laser Scanning Confocal Microscopy. • 3D morphology of persistent slip markings and twins was characterized. • Non-uniform deformation among grains, the PSMs and twins were quantified. • Initiations of fatigue crack were clearly investigated.« less

  18. Growth, structural, optical, thermal and laser damage threshold studies of an organic single crystal: 1,3,5 – triphenylbenzene (TPB)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Raja, R. Subramaniyan; Babu, G. Anandha; Ramasamy, P., E-mail: E-mail-ramasamyp@ssn.edu.in

    2016-05-23

    Good quality single crystals of pure hydrocarbon 1,3,5-Triphenylbenzene (TPB) have been successfully grown using toluene as a solvent using controlled slow cooling solution growth technique. TPB crystallizes in orthorhombic structure with the space group Pna2{sub 1}. The structural perfection of the grown crystal has been analysed by high resolution X-ray diffraction measurements. The range and percentage of the optical transmission are ascertained by recording the UV-vis spectrum. Thermo gravimetric analysis (TGA) and differential thermal analysis (DTA) were used to study its thermal properties. Powder second harmonic generation studies were carried out to explore its NLO properties. Laser damage threshold valuemore » has been determined using Nd:YAG laser operating at 1064 nm.« less

  19. Root causes investigation of catastrophic optical bulk damage in high-power InGaAs-AlGaAs strained QW lasers

    NASA Astrophysics Data System (ADS)

    Sin, Yongkun; Lingley, Zachary; Ayvazian, Talin; Brodie, Miles; Ives, Neil

    2018-02-01

    High-power single-mode (SM) and multi-mode (MM) InGaAs-AlGaAs strained quantum well (QW) lasers are critical components for both terrestrial and space satellite communications systems. Since these lasers predominantly fail by catastrophic and sudden degradation due to COD, it is especially crucial for space satellite applications to investigate reliability, failure modes, and degradation mechanisms of these lasers. Our group reported a new failure mode in MM and SM InGaAs-AlGaAs strained QW lasers in 2009 and 2016, respectively. Our group also reported in 2017 that bulk failure due to catastrophic optical bulk damage (COBD) is the dominant failure mode of both SM and MM lasers that were subject to long-term life-tests. For the present study, we report root causes investigation of COBD by performing long-term lifetests followed by failure mode analysis (FMA) using various micro-analytical techniques including electron beam induced current (EBIC), time-resolved electroluminescence (EL), focused ion beam (FIB), high-resolution transmission electron microscopy (TEM), and deep level transient spectroscopy (DLTS). Our life-tests with accumulated test hours of over 25,000 hours for SM lasers and over 35,000 hours for MM lasers generated a number of COBD failures with various failure times. EBIC techniques were employed to study dark line defects (DLDs) generated in SM COBD failures stressed under different test conditions. FIB and high-resolution TEM were employed to prepare cross sectional and plan view TEM specimens to study DLD areas (dislocations) in post-aged SM lasers. Time-resolved EL techniques were employed to study initiation and progressions of dark spots and dark lines in real time as MM lasers were aged. Lastly, to investigate precursor signatures of failure and degradation mechanisms responsible for COBD in both SM and MM lasers, we employed DLTS techniques to study a role that electron traps (non-radiative recombination centers) play in degradation of these

  20. Cutting efficiency of a mid-infrared laser on human enamel.

    PubMed

    Levy, G; Koubi, G F; Miserendino, L J

    1998-02-01

    In this study, the cutting ability of a newly developed dental laser was compared with a dental high-speed handpiece and rotary bur for removal of enamel. Measurements of the volume of tissue removed, energy emitted, and time of exposure were used to quantify the ablation rate (rate of tissue removal) for each test group and compared. Cutting efficiency (mm3/s) of the laser was calculated based on the mean volume of tissue removed per pulse (mm3/pulse) and unit energy expended (mm3/J) over the range of applied powers (2, 4, 6, and 8 W). The specimens were then examined by light microscopy and scanning electron micrographs for qualitative analysis of the amount of remaining debris and the presence of the smear layer on the prepared enamel surface. Calculations of the cutting efficiency of the laser over the range of powers tested revealed a linear relationship with the level of applied power. The maximum average rate of tissue removal by the laser was 0.256 mm3/s at 8 W, compared with 0.945 mm3/s by the dental handpiece. Light microscopy and scanning electron micrograph examinations revealed a reduction in the amount of remaining debris and smear layer in the laser-prepared enamel surfaces, compared with the conventional method. Based on the results of this study, the cutting efficiency of the high-speed handpiece and dental bur was 3.7 times greater than the laser over the range of powers tested, but the laser appeared to create a cleaner enamel surface with minimal thermal damage. Further modifications of the laser system are suggested for improvement of laser cutting efficiency.

  1. Laser-based sensors on UAVs for quantifying local emissions of greenhouse gases

    NASA Astrophysics Data System (ADS)

    Zondlo, Mark; Tao, Lei; O'Brien, Anthony; Ross, Kevin; Khan, Amir; Pan, Da; Golston, Levi; Sun, Kang; DiGangi, Josh

    2015-04-01

    well above the surface (up to 100 m). In addition, plumes were very narrow horizontally (10-30 m width) within 200 m of the emission origin. By using a mass balance approach of upwind versus downwind CH4 concentrations, coupled to meteorological wind data, the CH4 emission rate from the compressor station averaged 13 ± 5 g CH4 s-1, consistent with individual, leak surveys measured within the compressor station itself. More recently, we developed a mid-infrared version of the same sensor using an antimonide laser at 3.3 microns. This sensor has a precision of 2 ppbv CH4 at 10 Hz, a mass of 1.3 kg, and consumes 10 W of power. Flight tests show the improved precision is capable of detecting methane leaks from landfills and cattle feedlots at higher altitudes (500 m) and greater distances downwind (several km) than the near infrared CH4 sensor. Sampling strategy is particularly important for not only UAS-based flight patterns but also sensor design. Many tradeoffs exist between the sampling density of the flight pattern, sensor precision, accuracy of wind data, and geographic isolation of the source of interest, and these will be discussed in the context of airborne-based CH4 measurements in the field. The development of compact yet robust trace gas sensors to be deployed on small UAS opens new capabilities for atmospheric sensing such as quantifying local source emissions (e.g. farms, well pads), vertical profiling of trace gases in a forest canopy, and trace gas distributions in complex areas (mountains, urban canyons).

  2. Photothermal effects of laser tissue soldering.

    PubMed

    McNally, K M; Sorg, B S; Welch, A J; Dawes, J M; Owen, E R

    1999-04-01

    Low-strength anastomoses and thermal damage of tissue are major concerns in laser tissue welding techniques where laser energy is used to induce thermal changes in the molecular structure of the tissues being joined, hence allowing them to bond together. Laser tissue soldering, on the other hand, is a bonding technique in which a protein solder is applied to the tissue surfaces to be joined, and laser energy is used to bond the solder to the tissue surfaces. The addition of protein solders to augment tissue repair procedures significantly reduces the problems of low strength and thermal damage associated with laser tissue welding techniques. Investigations were conducted to determine optimal solder and laser parameters for tissue repair in terms of tensile strength, temperature rise and damage and the microscopic nature of the bonds formed. An in vitro study was performed using an 808 nm diode laser in conjunction with indocyanine green (ICG)-doped albumin protein solders to repair bovine aorta specimens. Liquid and solid protein solders prepared from 25% and 60% bovine serum albumin (BSA), respectively, were compared. The efficacy of temperature feedback control in enhancing the soldering process was also investigated. Increasing the BSA concentration from 25% to 60% greatly increased the tensile strength of the repairs. A reduction in dye concentration from 2.5 mg ml(-1) to 0.25 mg ml(-1) was also found to result in an increase in tensile strength. Increasing the laser irradiance and thus surface temperature resulted in an increased severity of histological injury. Thermal denaturation of tissue collagen and necrosis of the intimal layer smooth muscle cells increased laterally and in depth with higher temperatures. The strongest repairs were produced with an irradiance of 6.4 W cm(-2) using a solid protein solder composed of 60% BSA and 0.25 mg ml(-1) ICG. Using this combination of laser and solder parameters, surface temperatures were observed to reach 85

  3. Retinal damage induced by mirror-reflected light from a laser pointer.

    PubMed

    Thanos, Solon; Böhm, Michael R R; Meyer zu Hörste, Melissa; Schmidt, Peter-Fritz

    2015-10-05

    The safety of laser pointers is a major public health issue since class I and II laser pointers are available worldwide and used as toys by children despite several reports cautioning such use. Here we present the first case of retinal injury caused by the laser beam of a toy laser pointer operated by a school boy and directed via the rear-view mirror of a bus into the eye of the driver. This case emphasises the great importance of cautious and appropriate use of low-energy laser pointers. Laser pointers of any class should not be made available to children because they are unlikely to understand the risks of such lasers when using them in play. 2015 BMJ Publishing Group Ltd.

  4. Comparative study of 1,064-nm laser-induced skin burn and thermal skin burn.

    PubMed

    Zhang, Yi-Ming; Ruan, Jing; Xiao, Rong; Zhang, Qiong; Huang, Yue-Sheng

    2013-01-01

    Infrared lasers are widely used in medicine, industry, and other fields. While science, medicine, and the society in general have benefited from the many practical uses of lasers, they also have inherent safety issues. Although several procedures have been put forward to protect the skin from non-specific laser-induced damage, individuals receiving laser therapy or researchers who use laser are still at risk for skin damage. This study aims to understand the interaction between laser and the skin, and to investigate the differences between the skin damage caused by 1,064-nm laser and common thermal burns. Skin lesions on Wistar rats were induced by a 1,064-nm CW laser at a maximum output of 40 W and by a copper brass bar attached to an HQ soldering iron. Histological sections of the lesions and the process of wound healing were evaluated. The widths of the epidermal necrosis and dermal denaturalization of each lesion were measured. To observe wound healing, the epithelial gap and wound gap were measured. Masson's trichrome and picrosirius red staining were also used to assess lesions and wound healing. The thermal damage induced by laser intensified significantly in both horizontal dimension and in vertical depth with increased duration of irradiation. Ten days after wounding, the dermal injuries induced by laser were more severe. Compared with the laser-induced skin damage, the skin burn induced by an HQ soldering iron did not show a similar development or increased in severity with the passage of time. The results of this study showed the pattern of skin damage induced by laser irradiation and a heated brass bar. This study also highlighted the difference between laser irradiation and thermal burn in terms of skin damage and wound healing, and offers insight for further treatment.

  5. Laser wafering for silicon solar.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Friedmann, Thomas Aquinas; Sweatt, William C.; Jared, Bradley Howell

    2011-03-01

    Current technology cuts solar Si wafers by a wire saw process, resulting in 50% 'kerf' loss when machining silicon from a boule or brick into a wafer. We want to develop a kerf-free laser wafering technology that promises to eliminate such wasteful wire saw processes and achieve up to a ten-fold decrease in the g/W{sub p} (grams/peak watt) polysilicon usage from the starting polysilicon material. Compared to today's technology, this will also reduce costs ({approx}20%), embodied energy, and green-house gas GHG emissions ({approx}50%). We will use short pulse laser illumination sharply focused by a solid immersion lens to produce subsurfacemore » damage in silicon such that wafers can be mechanically cleaved from a boule or brick. For this concept to succeed, we will need to develop optics, lasers, cleaving, and high throughput processing technologies capable of producing wafers with thicknesses < 50 {micro}m with high throughput (< 10 sec./wafer). Wafer thickness scaling is the 'Moore's Law' of silicon solar. Our concept will allow solar manufacturers to skip entire generations of scaling and achieve grid parity with commercial electricity rates. Yet, this idea is largely untested and a simple demonstration is needed to provide credibility for a larger scale research and development program. The purpose of this project is to lay the groundwork to demonstrate the feasibility of laser wafering. First, to design and procure on optic train suitable for producing subsurface damage in silicon with the required damage and stress profile to promote lateral cleavage of silicon. Second, to use an existing laser to produce subsurface damage in silicon, and third, to characterize the damage using scanning electron microscopy and confocal Raman spectroscopy mapping.« less

  6. Interlaboratory study for nickel alloy 625 made by laser powder bed fusion to quantify mechanical property variability.

    PubMed

    Brown, Christopher U; Jacob, Gregor; Stoudt, Mark; Moylan, Shawn; Slotwinski, John; Donmez, Alkan

    2016-08-01

    Six different organizations participated in this interlaboratory study to quantify the variability in the tensile properties of Inconel 625 specimens manufactured using laser-powder-bed-fusion additive manufacturing machines. The tensile specimens were heat treated and tensile tests conducted until failure. The properties measured were yield strength, ultimate tensile strength, elastic modulus, and elongation. Statistical analysis revealed that between-participant variability for yield strength, ultimate tensile strength, and elastic modulus values were significantly higher (up to 4 times) than typical within-participant variations. Only between-participant and within-participant variability were both similar for elongation. A scanning electron microscope was used to examine one tensile specimen for fractography. The fracture surface does not have many secondary cracks or other features that would reduce the mechanical properties. In fact, the features largely consist of microvoid coalescence and are entirely consistent with ductile failure.

  7. Interlaboratory Study for Nickel Alloy 625 Made by Laser Powder Bed Fusion to Quantify Mechanical Property Variability

    NASA Astrophysics Data System (ADS)

    Brown, Christopher U.; Jacob, Gregor; Stoudt, Mark; Moylan, Shawn; Slotwinski, John; Donmez, Alkan

    2016-08-01

    Six different organizations participated in this interlaboratory study to quantify the variability in the tensile properties of Inconel 625 specimens manufactured using laser powder bed fusion-additive manufacturing machines. The tensile specimens were heat treated and tensile tests were conducted until failure. The properties measured were yield strength, ultimate tensile strength, elastic modulus, and elongation. Statistical analysis revealed that between-participant variability for yield strength, ultimate tensile strength, and elastic modulus values were significantly higher (up to four times) than typical within-participant variations. Only between-participant and within-participant variability were both similar for elongation. A scanning electron microscope was used to examine one tensile specimen for fractography. The fracture surface does not have many secondary cracks or other features that would reduce the mechanical properties. In fact, the features largely consist of microvoid coalescence and are entirely consistent with ductile failure.

  8. Lasers in orthodontics

    PubMed Central

    Nalcaci, Ruhi; Cokakoglu, Serpil

    2013-01-01

    Many types of dental lasers are currently available that can be efficiently used for soft and hard tissue applications in the field of orthodontics. For achieving the desired effects in the target tissue, knowledge of laser characteristics such as power, wavelength and timing, is necessary. Laser therapy is advantageous because it often avoids bleeding, can be pain free, is non-invasive and is relatively quick. The high cost is its primary disadvantage. It is very important to take the necessary precautions to prevent possible tissue damage when using laser dental systems. Here, we reviewed the main types and characteristics of laser systems used in dental practice and discuss the applications of lasers in orthodontics, harmful effects and laser system safety. PMID:24966719

  9. Precision machining of pig intestine using ultrafast laser pulses

    NASA Astrophysics Data System (ADS)

    Beck, Rainer J.; Góra, Wojciech S.; Carter, Richard M.; Gunadi, Sonny; Jayne, David; Hand, Duncan P.; Shephard, Jonathan D.

    2015-07-01

    Endoluminal surgery for the treatment of early stage colorectal cancer is typically based on electrocautery tools which imply restrictions on precision and the risk of harm through collateral thermal damage to the healthy tissue. As a potential alternative to mitigate these drawbacks we present laser machining of pig intestine by means of picosecond laser pulses. The high intensities of an ultrafast laser enable nonlinear absorption processes and a predominantly nonthermal ablation regime. Laser ablation results of square cavities with comparable thickness to early stage colorectal cancers are presented for a wavelength of 1030 nm using an industrial picosecond laser. The corresponding histology sections exhibit only minimal collateral damage to the surrounding tissue. The depth of the ablation can be controlled precisely by means of the pulse energy. Overall, the application of ultrafast lasers to ablate pig intestine enables significantly improved precision and reduced thermal damage to the surrounding tissue compared to conventional techniques.

  10. Pulse Compression Techniques for Laser Generated Ultrasound

    NASA Technical Reports Server (NTRS)

    Anastasi, R. F.; Madaras, E. I.

    1999-01-01

    Laser generated ultrasound for nondestructive evaluation has an optical power density limit due to rapid high heating that causes material damage. This damage threshold limits the generated ultrasound amplitude, which impacts nondestructive evaluation inspection capability. To increase ultrasound signal levels and improve the ultrasound signal-to-noise ratio without exceeding laser power limitations, it is possible to use pulse compression techniques. The approach illustrated here uses a 150mW laser-diode modulated with a pseudo-random sequence and signal correlation. Results demonstrate the successful generation of ultrasonic bulk waves in aluminum and graphite-epoxy composite materials using a modulated low-power laser diode and illustrate ultrasound bandwidth control.

  11. Using NASA`s Airborne Topographic Mapper IV to Quantify Geomorphic Change in Arid Southwestern Stream Systems

    NASA Astrophysics Data System (ADS)

    Finnegan, D. C.; Krabill, W.; Lichvar, R. W.; Ericsson, M. P.; Frederick, E.; Manizade, S.; Yungel, J.; Sonntag, J.; Swift, R.

    2005-12-01

    Understanding how arid stream systems respond to individual climatic events is often difficult given the dynamic and `flashy' nature of most watersheds and the unpredictable nature of individual storm events. Until recently conventional methods for quantifying change dictated the use of stream gauge measurements coupled with periodic cross-section measurements to quantify changes in large-scale channel geometry. Using this approach to quantify change across large areas often proves to be impractical and unattainable given the laborious nature of most surveying techniques including modern GPS systems. Alternately, airborne laser technologies such as NASA's Airborne Topographic Mapper (ATM) are capable of quantifying small-scale changes (~5-10cm) across large-scale terrain rapidly and accurately. The ATM was developed at the NASA-GSFC Wallops Flight Facility. Its current version, ATM-4, measures topography 5,000 times per second across a 45-degree swath below the aircraft by transmitting a 532nm (green) laser pulse and receiving the backscattered signal in a high-speed waveform digitizer. The laser range measurements are combined with aircraft location from GPS and attitude from an inertial navigation system (INS) to provide a precise XYZ coordinate for each (~1-meter diameter) laser footprint on the ground. Our work focuses on the use of airborne laser altimetry to quantify the nature of individual surfaces and the geomorphic change that occurs within small arid stream systems during significant storm events. In September of 2003 and 2005 acquisition surveys using NASA's ATM-IV were flown over Mission Creek, a small arid stream system in Southern California's Mojave Desert with a relatively long gauging history (>40yrs), allowing us to quantify the geomorphic change occurring within the channel as a result of the record storm events during the winter of 2004-2005. Preliminary results associated with our work are encouraging and lead us to believe that when compared

  12. Nanosecond pulse lasers for retinal applications.

    PubMed

    Wood, John P M; Plunkett, Malcolm; Previn, Victor; Chidlow, Glyn; Casson, Robert J

    2011-08-01

    Thermal lasers are routinely used to treat certain retinal disorders although they cause collateral damage to photoreceptors. The current study evaluated a confined, non-conductive thermal, 3-nanosecond pulse laser in order to determine how to produce the greatest therapeutic range without causing collateral damage. Data were compared with that obtained from a standard thermal laser. Porcine ocular explants were used; apposed neuroretina was also in place for actual laser treatment. After treatment, the retina was removed and a calcein-AM assay was used to assess retinal pigmented epithelium (RPE) cell viability in the explants. Histological methods were also employed to examine lased transverse explant sections. Three nanoseconds pulse lasers with either speckle- or gaussian-beam profile were employed in the study. Comparisons were made with a 100 milliseconds continuous wave (CW) 532 nm laser. The therapeutic energy range ratio was defined as the minimum visible effect threshold (VET) versus the minimum detectable RPE kill threshold. The 3-nanosecond lasers produced markedly lower minimum RPE kill threshold levels than the CW laser (e.g., 36 mJ/cm(2) for speckle-beam and 89 mJ/cm(2) for gaussian-beam profile nanosecond lasers vs. 7,958 mJ/cm(2) for CW laser). VET values were also correspondingly lower for the nanosecond lasers (130 mJ/cm(2) for 3 nanoseconds speckle-beam and 219 mJ/cm(2) for gaussian-beam profile vs. 1,0346 mJ/cm(2) for CW laser). Thus, the therapeutic range ratios obtained with the nanosecond lasers were much more favorable than that obtained by the CW laser: 3.6:1 for the speckle-beam and 2.5:1 for the gaussian-beam profile 3-nanosecond lasers versus 1.3:1 for the CW laser. Nanosecond lasers, particularly with a speckle-beam profile, provide a much wider therapeutic range of energies over which RPE treatment can be performed, without damage to the apposed retina, as compared with conventional CW lasers. These results may have

  13. Thermal comparison of buried-heterostructure and shallow-ridge lasers

    NASA Astrophysics Data System (ADS)

    Rustichelli, V.; Lemaître, F.; Ambrosius, H. P. M. M.; Brenot, R.; Williams, K. A.

    2018-02-01

    We present finite difference thermal modeling to predict temperature distribution, heat flux, and thermal resistance inside lasers with different waveguide geometries. We provide a quantitative experimental and theoretical comparison of the thermal behavior of shallow-ridge (SR) and buried-heterostructure (BH) lasers. We investigate the influence of a split heat source to describe p-layer Joule heating and nonradiative energy loss in the active layer and the heat-sinking from top as well as bottom when quantifying thermal impedance. From both measured values and numerical modeling we can quantify the thermal resistance for BH lasers and SR lasers, showing an improved thermal performance from 50K/W to 30K/W for otherwise equivalent BH laser designs.

  14. Laser surgery: using the carbon dioxide laser.

    PubMed Central

    Wright, V. C.

    1982-01-01

    In 1917 Einstein theorized tha through an atomic process a unique kind of electromagnetic radiation could be produced by stimulated emission. When such radiation is in the optical or infrared spectrum it is termed laser (light amplification by stimulated emission of radiation) light. A laser, a high-intensity light source, emits a nearly parallel electromagnetic beam of energy at a given wavelength that can be captured by a lens and concentrated in the focal spot. The wavelength determines how the laser will be used. The carbon dioxide laser is now successfully employed for some surgical procedures in gynecology, otorhinolaryngology, neurosurgery, and plastic and general surgery. The CO2 laser beam is directed through the viewing system of an operating microscope or through a hand-held laser component. Its basic action in tissue is thermal vaporization; it causes minimal damage to adjacent tissues. Surgeons require special training in the basic methods and techniques of laser surgery, as well as in the safety standards that must be observed. Images FIG. 5 PMID:7074503

  15. Quantifying Lygus lineolaris stylet probing behavior and its damage to cotton leaf terminals

    USDA-ARS?s Scientific Manuscript database

    Lygus lineolaris is a serious pest inducing feeding damage on an array of crops; on cotton, lygus bugs feed on both leaves and squares. When lygus bugs feed on cotton leaves, younger leaves at cotton axials and terminals are preferred; resulting damage may compromise plant growth. Because L. lineola...

  16. Er,CR:YSGG lasers induce fewer dysplastic-like epithelial artefacts than CO2 lasers: an in vivo experimental study on oral mucosa.

    PubMed

    González-Mosquera, A; Seoane, J; García-Caballero, L; López-Jornet, P; García-Caballero, T; Varela-Centelles, P

    2012-09-01

    Our aim was to assess wounds made by lasers (CO(2) and Er,Cr:YSGG) for their epithelial architectural changes and width of damage. We allocated 60 Sprague-Dawley(®) rats into groups: glossectomy by CO(2) laser at 3 different wattages (n=10 in each); glossectomy by Er,Cr:YSGG laser at two different emissions (n=10 in each), and a control group (n=10). Histological examination assessed both prevalence and site of thermal artefacts for each group. Both lasers (CO(2) and Er,Cr:YSGG) caused the same type of cytological artefacts. The 3W Er,Cr:YSGG laser produced the fewest cytological artefacts/specimen, and was significantly different from the other experimental groups: 3W CO(2) laser (95% CI=0.8 to 1.0); the 6W CO(2) laser (95% CI=0.1 to 2.0) and the 10W CO(2) laser (95% CI=1.1 to 3.0). CO(2) lasers (3-10W) generate epithelial damage that can simulate dysplastic changes with cytological atypia that affects mainly the basal and suprabasal layers. Irradiation with Er,CR:YSGG laser (2-4W) produces significantly fewer cellular artefacts and less epithelial damage, which may be potentially useful for biopsy of oral mucosa. Copyright © 2011 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

  17. Fundamental mechanisms of laser damage of dielectric crystals by ultrashort pulse: ionization dynamics for the Keldysh model

    NASA Astrophysics Data System (ADS)

    Gruzdev, Vitaly

    2014-12-01

    Laser-induced ionization is a major process that initiates and drives the initial stages of laser-induced damage (LID) of high-quality transparent solids. The ionization and its contribution to LID are characterized in terms of the time-dependent ionization rate and conduction-band electron density. Considering femtosecond pulses of various durations (from 35 to 706 fs) and variable peak irradiances (from 0.01 to 60 TW/cm2), we use a single-rate equation to simulate time variations of conduction-band electron density and rates of the photoionization and impact ionization. The photoionization rate is evaluated with the Keldysh equation. At low irradiance, the electron density and total ionization rate demonstrate power scaling characteristic of multiphoton ionization. With the increase of irradiance, there is observed a saturation of the photoionization rate due to photoionization suppression by the Keldysh-type singularity during the increase in the number of simultaneously absorbed photons by 1. A striking result is that the saturation is followed by a stepwise transition from the ionization regime which is completely dominated by the photoionization to a regime totally dominated by the impact ionization. The transition results in the increase of the electron density by a few orders of magnitude induced by a variation of peak laser irradiance by about 15% to 20%. The physical effects that are involved are discussed.

  18. Laser cleaning on Roman coins

    NASA Astrophysics Data System (ADS)

    Drakaki, E.; Karydas, A. G.; Klinkenberg, B.; Kokkoris, M.; Serafetinides, A. A.; Stavrou, E.; Vlastou, R.; Zarkadas, C.

    Ancient metal objects react with moisture and environmental chemicals to form various corrosion products. Because of the unique character and high value of such objects, any cleaning procedure should guarantee minimum destructiveness. The most common treatment used is mechanical stripping, in which it is difficult to avoid surface damage when employed. Lasers are currently being tested for a wide range of conservation applications. Since they are highly controllable and can be selectively applied, lasers can be used to achieve more effective and safer cleaning of archaeological artifacts and protect their surface details. The basic criterion that motivated us to use lasers to clean Roman coins was the requirement of pulsed emission, in order to minimize heat-induced damages. In fact, the laser interaction with the coins has to be short enough, to produce a fast removal of the encrustation, avoiding heat conduction into the substrate. The cleaning effects of three lasers operating at different wavelengths, namely a TEA CO2 laser emitting at 10.6 μm, an Er:YAG laser at 2.94 μm, and a 2ω-Nd:YAG laser at 532 nm have been compared on corroded Romans coins and various atomic and nuclear techniques have also been applied to evaluate the efficiency of the applied procedure.

  19. Toward robot-assisted neurosurgical lasers.

    PubMed

    Motkoski, Jason W; Yang, Fang Wei; Lwu, Shelly H H; Sutherland, Garnette R

    2013-04-01

    Despite the potential increase in precision and accuracy, laser technology is not widely used in neurological surgery. This in part relates to challenges associated with the early introduction of lasers into neurosurgery. Considerable advances in laser technology have occurred, which together with robotic technology could create an ideal platform for neurosurgical application. In this study, a 980-nm contact diode laser was integrated with neuroArm. Preclinical evaluation involved partial hepatectomy, bilateral nephrectomy, splenectomy, and bilateral submandibular gland excision in a Sprague-Dawley rat model (n = 50). Total surgical time, blood loss as weight of surgical gauze before and after the procedure, and the incidence of thermal, vascular, or lethal injury were recorded and converted to an overall performance score. Thermal damage was evaluated in the liver using tissue samples stained with hematoxylin and eosin. Clinical studies involved step-wise integration of the 980-nm laser system into four neurosurgical cases. Results demonstrate the successful integration of contact laser technology into microsurgery, with and without robotic assistance. In preclinical studies, the laser improved microsurgical performance and reduced thermal damage, while neuroArm decreased intra- and intersurgeon variability. Clinical studies demonstrate dutility in meningioma resection (n = 4). Together, laser and robotic technology offered a more consistent, expedient, and precise tool for microsurgery.

  20. Interlaboratory study for nickel alloy 625 made by laser powder bed fusion to quantify mechanical property variability

    PubMed Central

    Brown, Christopher U.; Jacob, Gregor; Stoudt, Mark; Moylan, Shawn; Slotwinski, John; Donmez, Alkan

    2017-01-01

    Six different organizations participated in this interlaboratory study to quantify the variability in the tensile properties of Inconel 625 specimens manufactured using laser-powder-bed-fusion additive manufacturing machines. The tensile specimens were heat treated and tensile tests conducted until failure. The properties measured were yield strength, ultimate tensile strength, elastic modulus, and elongation. Statistical analysis revealed that between-participant variability for yield strength, ultimate tensile strength, and elastic modulus values were significantly higher (up to 4 times) than typical within-participant variations. Only between-participant and within-participant variability were both similar for elongation. A scanning electron microscope was used to examine one tensile specimen for fractography. The fracture surface does not have many secondary cracks or other features that would reduce the mechanical properties. In fact, the features largely consist of microvoid coalescence and are entirely consistent with ductile failure. PMID:28243032

  1. New counter-countermeasure techniques for laser anti-dazzling spectacles

    NASA Astrophysics Data System (ADS)

    Donval, Ariela; Partouche, Eran; Lipman, Ofir; Gross, Noam; Fisher, Tali; Oron, Moshe

    2016-05-01

    Aviation, commercial and military, is new area in optics that is suffering from laser threats in the last years. Dazzling and damage to pilot's eyes by laser pointers is a common threat lately. Under certain conditions, laser light, directed at aircraft can be hazardous. The most likely scenario is when bright visible laser light causes distraction and/or temporary flash blindness to the pilot, during a critical phase of flight like landing or takeoff. It is also possible, that a visible or invisible beam could cause permanent damage to a pilot's eyes. This paper presents a novel technology for protection of the human eye against laser threats in the visible range.

  2. Numerical analysis of breakdown dynamics dependence on pulse width in laser-induced damage in fused silica: Role of optical system

    NASA Astrophysics Data System (ADS)

    Hamam, Kholoud A.; Gamal, Yosr E. E.-D.

    2018-06-01

    We report a numerical investigation of the breakdown and damage in fused silica caused by ultra-short laser pulses. The study based on a modified model (Gaabour et al., 2012) that solves the rate equation numerically for the electron density evolution during the laser pulse, under the combined effect of both multiphoton and electron impact ionization processes. Besides, electron loss processes due to diffusion out of the focal volume and recombination are also considered in this analysis. The model is applied to investigate the threshold intensity dependence on laser pulse width in the experimental measurements that are given by Liu et al. (2005). In this experiment, a Ti-sapphire laser source operating at 800 nm with pulse duration varies between 240 fs and 2.5 ps is used to irradiate a bulk of fused silica with dimensions 10 × 5 × 3 mm. The laser beam was focused into the bulk using two optical systems with effective numerical apertures (NA) 0.126 and 0.255 to give beam spot radius at the focus of the order 2.0 μm and 0.95 μm respectively. Reasonable agreement between the calculated thresholds and the measured ones is attained. Moreover, a study is performed to examine the respective role of the physical processes of the breakdown of fused silica in relation to the pulse width and focusing optical system. The analysis revealed a real picture of the location and size of the generated plasma.

  3. Quantifying progression and regression of thrombotic risk in experimental atherosclerosis

    PubMed Central

    Palekar, Rohun U.; Jallouk, Andrew P.; Goette, Matthew J.; Chen, Junjie; Myerson, Jacob W.; Allen, John S.; Akk, Antonina; Yang, Lihua; Tu, Yizheng; Miller, Mark J.; Pham, Christine T. N.; Wickline, Samuel A.; Pan, Hua

    2015-01-01

    Currently, there are no generally applicable noninvasive methods for defining the relationship between atherosclerotic vascular damage and risk of focal thrombosis. Herein, we demonstrate methods to delineate the progression and regression of vascular damage in response to an atherogenic diet by quantifying the in vivo accumulation of semipermeable 200–300 nm perfluorocarbon core nanoparticles (PFC-NP) in ApoE null mouse plaques with [19F] magnetic resonance spectroscopy (MRS). Permeability to PFC-NP remained minimal until 12 weeks on diet, then increased rapidly following 12 weeks, but regressed to baseline within 8 weeks after diet normalization. Markedly accelerated clotting (53.3% decrease in clotting time) was observed in carotid artery preparations of fat-fed mice subjected to photochemical injury as defined by the time to flow cessation. For all mice on and off diet, an inverse linear relationship was observed between the permeability to PFC-NP and accelerated thrombosis (P = 0.02). Translational feasibility for quantifying plaque permeability and vascular damage in vivo was demonstrated with clinical 3 T MRI of PFC-NP accumulating in plaques of atherosclerotic rabbits. These observations suggest that excessive permeability to PFC-NP may indicate prothrombotic risk in damaged atherosclerotic vasculature, which resolves within weeks after dietary therapy.—Palekar, R. U., Jallouk, A. P., Goette, M. J., Chen, J., Myerson, J. W., Allen, J. S., Akk, A., Yang, L., Tu, Y., Miller, M. J., Pham, C. T. N., Wickline, S. A., Pan, H. Quantifying progression and regression of thrombotic risk in experimental atherosclerosis. PMID:25857553

  4. Optical coherence tomography-guided laser microsurgery for blood coagulation with continuous-wave laser diode.

    PubMed

    Chang, Feng-Yu; Tsai, Meng-Tsan; Wang, Zu-Yi; Chi, Chun-Kai; Lee, Cheng-Kuang; Yang, Chih-Hsun; Chan, Ming-Che; Lee, Ya-Ju

    2015-11-16

    Blood coagulation is the clotting and subsequent dissolution of the clot following repair to the damaged tissue. However, inducing blood coagulation is difficult for some patients with homeostasis dysfunction or during surgery. In this study, we proposed a method to develop an integrated system that combines optical coherence tomography (OCT) and laser microsurgery for blood coagulation. Also, an algorithm for positioning of the treatment location from OCT images was developed. With OCT scanning, 2D/3D OCT images and angiography of tissue can be obtained simultaneously, enabling to noninvasively reconstruct the morphological and microvascular structures for real-time monitoring of changes in biological tissues during laser microsurgery. Instead of high-cost pulsed lasers, continuous-wave laser diodes (CW-LDs) with the central wavelengths of 450 nm and 532 nm are used for blood coagulation, corresponding to higher absorption coefficients of oxyhemoglobin and deoxyhemoglobin. Experimental results showed that the location of laser exposure can be accurately controlled with the proposed approach of imaging-based feedback positioning. Moreover, blood coagulation can be efficiently induced by CW-LDs and the coagulation process can be monitored in real-time with OCT. This technology enables to potentially provide accurate positioning for laser microsurgery and control the laser exposure to avoid extra damage by real-time OCT imaging.

  5. Optical coherence tomography-guided laser microsurgery for blood coagulation with continuous-wave laser diode

    NASA Astrophysics Data System (ADS)

    Chang, Feng-Yu; Tsai, Meng-Tsan; Wang, Zu-Yi; Chi, Chun-Kai; Lee, Cheng-Kuang; Yang, Chih-Hsun; Chan, Ming-Che; Lee, Ya-Ju

    2015-11-01

    Blood coagulation is the clotting and subsequent dissolution of the clot following repair to the damaged tissue. However, inducing blood coagulation is difficult for some patients with homeostasis dysfunction or during surgery. In this study, we proposed a method to develop an integrated system that combines optical coherence tomography (OCT) and laser microsurgery for blood coagulation. Also, an algorithm for positioning of the treatment location from OCT images was developed. With OCT scanning, 2D/3D OCT images and angiography of tissue can be obtained simultaneously, enabling to noninvasively reconstruct the morphological and microvascular structures for real-time monitoring of changes in biological tissues during laser microsurgery. Instead of high-cost pulsed lasers, continuous-wave laser diodes (CW-LDs) with the central wavelengths of 450 nm and 532 nm are used for blood coagulation, corresponding to higher absorption coefficients of oxyhemoglobin and deoxyhemoglobin. Experimental results showed that the location of laser exposure can be accurately controlled with the proposed approach of imaging-based feedback positioning. Moreover, blood coagulation can be efficiently induced by CW-LDs and the coagulation process can be monitored in real-time with OCT. This technology enables to potentially provide accurate positioning for laser microsurgery and control the laser exposure to avoid extra damage by real-time OCT imaging.

  6. Evaluation damage threshold of optical thin-film using an amplified spontaneous emission source

    NASA Astrophysics Data System (ADS)

    Zhou, Qiong; Sun, Mingying; Zhang, Zhixiang; Yao, Yudong; Peng, Yujie; Liu, Dean; Zhu, Jianqiang

    2014-10-01

    An accurate evaluation method with an amplified spontaneous emission (ASE) as the irradiation source has been developed for testing thin-film damage threshold. The partial coherence of the ASE source results in a very smooth beam profile in the near-field and a uniform intensity distribution of the focal spot in the far-field. ASE is generated by an Nd: glass rod amplifier in SG-II high power laser facility, with pulse duration of 9 ns and spectral width (FWHM) of 1 nm. The damage threshold of the TiO2 high reflection film is 14.4J/cm2 using ASE as the irradiation source, about twice of 7.4 J/cm2 that tested by a laser source with the same pulse duration and central wavelength. The damage area induced by ASE is small with small-scale desquamation and a few pits, corresponding to the defect distribution of samples. Large area desquamation is observed in the area damaged by laser, as the main reason that the non-uniformity of the laser light. The ASE damage threshold leads to more accurate evaluations of the samples damage probability by reducing the influence of hot spots in the irradiation beam. Furthermore, the ASE source has a great potential in the detection of the defect distribution of the optical elements.

  7. Quantifying the correlation between photoplethysmography and laser Doppler flowmetry microvascular low-frequency oscillations

    NASA Astrophysics Data System (ADS)

    Mizeva, Irina; Di Maria, Costanzo; Frick, Peter; Podtaev, Sergey; Allen, John

    2015-03-01

    Photoplethysmography (PPG) and laser Doppler flowmetry (LDF) are two recognized optical techniques that can track low-frequency perfusion changes in microcirculation. The aim of this study was to determine, in healthy subjects, the correlation between the techniques for specific low-frequency bands previously defined for microcirculation. Twelve healthy male subjects (age range 18 to 50 years) were studied, with PPG and LDF signals recorded for 20 min from their right and left index (PPG) and middle (LDF) fingers. Wavelet analysis comprised dividing the low-frequency integral wavelet spectrum (IWS) into five established physiological bands relating to cardiac, respiratory, myogenic, neurogenic, and endothelial activities. The correlation between PPG and LDF was quantified using wavelet correlation analysis and Spearman correlation analysis of the median IWS amplitude. The median wavelet correlation between signals (right-left side average) was 0.45 (cardiac), 0.49 (respiratory), 0.86 (myogenic), 0.91 (neurogenic), and 0.91 (endothelial). The correlation of IWS amplitude values (right-left side average) was statistically significant for the cardiac (ρ=0.64, p<0.05) and endothelial (ρ=0.62, p<0.05) bands. This pilot study has shown good correlation between PPG and LDF for specific physiological frequency bands. In particular, the results suggest that PPG has the potential to be a low-cost replacement for LDF for endothelial activity assessments.

  8. Low power lasers on genomic stability.

    PubMed

    Trajano, Larissa Alexsandra da Silva Neto; Sergio, Luiz Philippe da Silva; Stumbo, Ana Carolina; Mencalha, Andre Luiz; Fonseca, Adenilson de Souza da

    2018-03-01

    Exposure of cells to genotoxic agents causes modifications in DNA, resulting to alterations in the genome. To reduce genomic instability, cells have DNA damage responses in which DNA repair proteins remove these lesions. Excessive free radicals cause DNA damages, repaired by base excision repair and nucleotide excision repair pathways. When non-oxidative lesions occur, genomic stability is maintained through checkpoints in which the cell cycle stops and DNA repair occurs. Telomere shortening is related to the development of various diseases, such as cancer. Low power lasers are used for treatment of a number of diseases, but they are also suggested to cause DNA damages at sub-lethal levels and alter transcript levels from DNA repair genes. This review focuses on genomic and telomere stabilization modulation as possible targets to improve therapeutic protocols based on low power lasers. Several studies have been carried out to evaluate the laser-induced effects on genome and telomere stabilization suggesting that exposure to these lasers modulates DNA repair mechanisms, telomere maintenance and genomic stabilization. Although the mechanisms are not well understood yet, low power lasers could be effective against DNA harmful agents by induction of DNA repair mechanisms and modulation of telomere maintenance and genomic stability. Copyright © 2018 Elsevier B.V. All rights reserved.

  9. Use of a microsecond Er:YAG laser in laryngeal surgery reduces collateral thermal injury in comparison to superpulsed CO2 laser.

    PubMed

    Böttcher, Arne; Jowett, Nathan; Kucher, Stanislav; Reimer, Rudolph; Schumacher, Udo; Knecht, Rainald; Wöllmer, Wolfgang; Münscher, Adrian; Dalchow, Carsten V

    2014-05-01

    Despite causing significant thermocoagulative insult, use of the carbon dioxide (CO2) laser is considered gold standard in surgery for early stage larynx carcinoma. Limited attention has been paid to the use of the erbium:yttrium-aluminium-garnet (Er:YAG) laser in laryngeal surgery as a means to reduce thermal tissue injury. The objective of this study is to compare the extent of thermal injury and precision of vocal fold incisions made using microsecond Er:YAG and superpulsed CO2 lasers. In the optics laboratory ex vivo porcine vocal folds were incised using Er:YAG and CO2 lasers. Lateral epithelial and subepithelial thermal damage zones and cutting gap widths were histologically determined. Environmental scanning electron microscopy (ESEM) images were examined for signs of carbonization. Temperature rise during Er:YAG laser incisions was determined using infrared thermography (IRT). In comparison to the CO2 laser, Er:YAG laser incisions showed significantly decreased epithelial (236.44 μm) and subepithelial (72.91 μm) damage zones (p < 0.001). Cutting gaps were significantly narrower for CO2 (878.72 μm) compared to Er:YAG (1090.78 μm; p = 0.027) laser. ESEM revealed intact collagen fibres along Er:YAG laser cutting edges without obvious carbonization, in comparison to diffuse carbonization and tissue melting seen for CO2 laser incisions. IRT demonstrated absolute temperature rise below 70 °C for Er:YAG laser incisions. This study has demonstrated significantly reduced lateral thermal damage zones with wider basal cutting gaps for vocal fold incisions made using Er:YAG laser in comparison to those made using CO2 laser.

  10. Property Investigation of Laser Cladded, Laser Melted and Electron Beam Melted Ti-Al6-V4

    DTIC Science & Technology

    2006-05-01

    UNCLASSIFIED/UNLIMITED UNCLASSIFIED/UNLIMITED Figure 3: Examples of electron beam melted net shape parts; powder bed [3]. 1.4 Laser Cladding ...description, www.arcam.com. [4] K.-H. Hermann, S. Orban, S. Nowotny, Laser Cladding of Titanium Alloy Ti6242 to Restore Damaged Blades, Proceedings...Property Investigation of Laser Cladded , Laser Melted and Electron Beam Melted Ti-Al6-V4 Johannes Vlcek EADS Deutschland GmbH Corporate Research

  11. Improvement of optical damage in specialty fiber at 266 nm wavelength

    NASA Astrophysics Data System (ADS)

    Tobisch, T.; Ohlmeyer, H.; Zimmermann, H.; Prein, S.; Kirchhof, J.; Unger, S.; Belz, M.; Klein, K.-F.

    2014-02-01

    Improved multimode UV-fibers with core diameters ranging from 70 to 600 μm diameter have been manufactured based on novel preform modifications and fiber processing techniques. Only E'-centers at 214 nm and NBOHC at 260 nm are generated in these fibers. A new generation of inexpensive laser-systems have entered the market and generated a multitude of new and attractive applications in the bio-life science, chemical and material processing field. However, for example pulsed 355 nm Nd:YAG lasers generate significant UV-damages in commercially available fibers. For lower wavelengths, no results on suitable multi-mode or low-mode fibers with high UV resistance at 266 nm wavelength (pulsed 4th harmonic Nd:YAG laser) have been published. In this report, double-clad fibers with 70 μm or 100 μm core diameter and a large claddingto- core ratio will be recommended. Laser-induced UV-damages will be compared between these new fiber type and traditional UV fibers with similar core sizes. Finally, experimental results will be cross compared against broadband cw deuterium lamp damage standards.

  12. Nanoparticles for diagnostics and laser medical treatment of cartilage in orthopaedics

    NASA Astrophysics Data System (ADS)

    Baum, O. I.; Soshnikova, Yu. M.; Omelchenko, A. I.; Sobol, Emil

    2013-02-01

    Laser reconstruction of intervertebral disc (LRD) is a new technique which uses local, non-destructive laser irradiation for the controlled activation of regenerative processes in a targeted zone of damaged disc cartilage. Despite pronounced advancements of LRD, existing treatments may be substantially improved if laser radiation is absorbed near diseased and/or damaged regions in cartilage so that required thermomechanical stress and strain at chondrocytes may be generated and non-specific injury reduced or eliminated. The aims of the work are to study possibility to use nanoparticles (NPs) to provide spatial specificity for laser regeneration of cartilage. Two types of porcine joint cartilage have been impregnated with magnetite NPs: 1) fresh cartilage; 2) mechanically damaged cartilage. NPs distribution was studied using transition electron microscopy, dynamic light scattering and analytical ultracentrifugation techniques. Laser radiation and magnetic field have been applied to accelerate NPs impregnation. It was shown that NPs penetrate by diffusion into the mechanically damaged cartilage, but do not infiltrate healthy cartilage. Temperature dynamics in cartilage impregnated with NPs have been theoretically calculated and measurements using an IR thermo vision system have been performed. Laser-induced alterations of cartilage structure and cellular surviving have been studied for cartilage impregnated with NPs using histological and histochemical techniques. Results of our study suggest that magnetite NPs might be used to provide spatial specificity of laser regeneration. When damaged, the regions of cartilage impreganted with NPs have higher absorption of laser radiation than that for healthy areas. Regions containing NPs form target sites that can be used to generate laser-induced thermo mechanical stress leading to regeneration of cartilage of hyaline type.

  13. Comparing the ISO-recommended and the cumulative data-reduction algorithms in S-on-1 laser damage test by a reverse approach method

    NASA Astrophysics Data System (ADS)

    Zorila, Alexandru; Stratan, Aurel; Nemes, George

    2018-01-01

    We compare the ISO-recommended (the standard) data-reduction algorithm used to determine the surface laser-induced damage threshold of optical materials by the S-on-1 test with two newly suggested algorithms, both named "cumulative" algorithms/methods, a regular one and a limit-case one, intended to perform in some respects better than the standard one. To avoid additional errors due to real experiments, a simulated test is performed, named the reverse approach. This approach simulates the real damage experiments, by generating artificial test-data of damaged and non-damaged sites, based on an assumed, known damage threshold fluence of the target and on a given probability distribution function to induce the damage. In this work, a database of 12 sets of test-data containing both damaged and non-damaged sites was generated by using four different reverse techniques and by assuming three specific damage probability distribution functions. The same value for the threshold fluence was assumed, and a Gaussian fluence distribution on each irradiated site was considered, as usual for the S-on-1 test. Each of the test-data was independently processed by the standard and by the two cumulative data-reduction algorithms, the resulting fitted probability distributions were compared with the initially assumed probability distribution functions, and the quantities used to compare these algorithms were determined. These quantities characterize the accuracy and the precision in determining the damage threshold and the goodness of fit of the damage probability curves. The results indicate that the accuracy in determining the absolute damage threshold is best for the ISO-recommended method, the precision is best for the limit-case of the cumulative method, and the goodness of fit estimator (adjusted R-squared) is almost the same for all three algorithms.

  14. Use of Lasers in Laryngeal Surgery

    PubMed Central

    Yan, Yan; Olszewski, Aleksandra E.; Hoffman, Matthew R.; Zhuang, Peiyun; Ford, Charles N.; Dailey, Seth H.; Jiang, Jack J.

    2012-01-01

    Lasers are a relatively recent addition to laryngeal surgery. Since their invention, laser use and applications have expanded rapidly. In this paper, we discuss the benefits and disadvantages of lasers for different procedures, as well as ways to overcome commonly faced clinical problems. The use of lasers in surgery has offered a time- and cost-efficient alternative to cold surgical techniques, and has been employed in the treatment of numerous laryngeal pathologies, including stenoses, recurrent respiratory papillomatosis, leukoplakia, nodules, malignant laryngeal disease, and polypoid degeneration (Reinke’s edema). However, lasers can incur adjacent tissue damage and vocal fold scarring. These problems can be minimized through understanding the mechanisms by which lasers function and correctly manipulating the parameters under a surgeon’s control. By varying fluence, power density, and pulsation, tissue damage can be decreased and lasers can be used with greater confidence. The various types of lasers and their applications to the treatment of specific pathologies are reviewed with the intention of helping surgeons select the best tool for a given procedure. Recent applications of lasers to treat benign laryngeal lesions and severe laryngomalacia demonstrate that additional research must be conducted in order to realize the full potential of this surgical tool. PMID:19487102

  15. How laser damage resistance of HfO2/SiO2 optical coatings is affected by embedded contamination caused by pausing the deposition process

    NASA Astrophysics Data System (ADS)

    Field, Ella; Bellum, John; Kletecka, Damon

    2015-07-01

    Reducing contamination is essential for producing optical coatings with high resistance to laser damage. One aspect of this principle is to make every effort to limit long interruptions during the coating's deposition. Otherwise, contamination may accumulate during the pause and become embedded in the coating after the deposition is restarted, leading to a lower laser-induced damage threshold (LIDT). However, pausing a deposition is sometimes unavoidable, despite our best efforts. For example, a sudden hardware or software glitch may require hours or even overnight to solve. In order to broaden our understanding of the role of embedded contamination on LIDT, and determine whether a coating deposited under such non-ideal circumstances could still be acceptable, this study explores how halting a deposition overnight impacts the LIDT, and whether ion cleaning can be used to mitigate any negative effects on the LIDT. The coatings investigated are a beam splitter design for high reflection at 1054 nm and high transmission at 527 nm, at 22.5° angle of incidence in S-polarization. LIDT tests were conducted in the nanosecond regime.

  16. Selective removal of dental composite using a rapidly scanned carbon dioxide laser

    NASA Astrophysics Data System (ADS)

    Chan, Kenneth H.; Fried, Daniel

    2011-03-01

    Dental restorative materials are color matched to the tooth and are difficult to remove by mechanical means without excessive removal or damage to peripheral enamel and dentin. Lasers are ideally suited for selective ablation to minimize healthy tissue loss when replacing existing restorations, sealants or removing composite adhesives such as residual composite left after debonding orthodontic brackets. In this study a carbon dioxide laser operating at high laser pulse repetition rates integrated with a galvanometer based scanner was used to selectively remove composite from tooth surfaces. A diode array spectrometer was used to measure the plume emission after each laser pulse and determine if the ablated material was tooth mineral or composite. The composite was placed on tooth buccal and occlusal surfaces and the carbon dioxide laser was scanned across the surface to selectively remove the composite without excessive damage to the underlying sound enamel. The residual composite and the damage to the underlying enamel was evaluated using optical microscopy. The laser was able to rapidly remove the composites rapidly from both surfaces with minimal damage to the underlying sound enamel.

  17. Heat effect of pulsed Er:YAG laser radiation

    NASA Astrophysics Data System (ADS)

    Hibst, Raimund; Keller, Ulrich

    1990-06-01

    Pulsed Er:YAG laser radiation has been found to be effective for dental enamel and dentin removal. Damage to the surrounding hard tissue is little, but before testing the Er:YAG laser clinically for the preparation of cavities, possible effects on the soft tissue of the pulp must be known. In order to estimate pulp damage , temperature rise in dentin caused by the laser radiation was measured by a thermocouple. Additionally, temperature distributions were observed by means of a thermal imaging system. The heat effect of a single Er:YAG laser pulse is little and limited to the vicinity of the impact side. Because heat energy is added with each additional pulse , the temperature distribution depends not only on the radiant energy, but also on the number of pulses and the repetition rate. Both irradiation conditions can be found , making irreversible pulp damage either likely or unlikely. The experimental observations can be explained qualitatively by a simple model of the ablation process.

  18. Genotoxic effects of 1064-nm Nd:YAG and 532-nm KTP lasers on fibroblast cell cultures.

    PubMed

    Senturk, N; Bedir, A; Bilgici, B; Aydin, F; Okuyucu, A; Ozmen, Z C; Turanli, A Y

    2010-07-01

    Several different laser types are used in cutaneous surgery. The neodymium:yttrium-aluminium-garnet (Nd:YAG) and frequency-doubled Nd:YAG (KTP, potassium titanyl phosphate) lasers are widely used in dermatology. To investigate the possible genotoxic effects on fibroblasts of irradiation with a 1064-nm Nd:YAG laser and a 532-nm KTP laser. Fibroblast cell cultures were exposed to each of the lasers, using 10-mm spot size at 60 ms pulse duration with 10, 20, 40 J/cm(2) and 3, 6, 12 J/cm(2) fluences, respectively. Fibroblasts in passages 1-6 were used. During laser irradiation, 96-well microplate cultures were kept on a cooling block and transported on ice and in the dark, and processed immediately for single-cell gel electrophoresis (SCGE) assay (also known as a comet assay). DNA damage was determined by computerized assessment of comet assay. There was increasing damage with increasing numbers of passages. For the Nd:YAG laser, the greatest damage occurred on passages 5 and 6, whereas the greatest damage appeared at passages 3 and 4 for KTP and returned to baseline at passages 5 and 6. Damage also increased with each dose increment for both wavelengths. At the highest dose for both wavelengths (Nd:YAG 40 J/cm(2) and KTP 12 J/cm(2)), damage was higher with the Nd:YAG laser. Different patterns of cellular damage were seen for different cell-culture passages, treatment doses, and laser wavelengths. These dose ranges are generally used for the treatment of vascular and pigmented lesions and for rejuvenation purposes. As replicative ageing or cell senescence is one of the critical factors determining the extent of cell damage induced by laser therapy, these results may have important implications for clinical practice.

  19. Femtosecond laser ablation of the stapes

    NASA Astrophysics Data System (ADS)

    McCaughey, Ryan G.; Sun, Hui; Rothholtz, Vanessa S.; Juhasz, Tibor; Wong, Brian J. F.

    2009-03-01

    A femtosecond laser, normally used for LASIK eye surgery, is used to perforate cadaveric human stapes. The thermal side effects of bone ablation are measured with a thermocouple in an inner ear model and are found to be within acceptable limits for inner ear surgery. Stress and acoustic events, recorded with piezoelectric film and a microphone, respectively, are found to be negligible. Optical microscopy, scanning electron microscopy, and optical coherence tomography are used to confirm the precision of the ablation craters and lack of damage to the surrounding tissue. Ablation is compared to that from an Er:YAG laser, the current laser of choice for stapedotomy, and is found to be superior. Ultra-short-pulsed lasers offer a precise and efficient ablation of the stapes, with minimal thermal and negligible mechanical and acoustic damage. They are, therefore, ideal for stapedotomy operations.

  20. Silver-free solar cell interconnection by laser spot welding of thin aluminum layers: analysis of process limits for ns- and μs-lasers

    NASA Astrophysics Data System (ADS)

    Schulte-Huxel, H.; Blankemeyer, S.; Kajari-Schröder, S.; Brendel, R.

    2014-03-01

    We investigate a laser welding process for contacting aluminum metallized crystalline silicon solar cells to a 10-μm-thick aluminum layers on a glass substrate. The reduction of the solar cell metallization thickness is analyzed with respect to laser induced damage using SiNx passivated silicon wafers. Additionally, we measure the mechanical stress of the laser welds by perpendicular tear-off as well as the electrical contact resistance. We apply two types of laser processes; one uses one to eight 20-ns-laser pulses at 355 nm with fluences between 12 and 40 J/cm2 and the other single 1.2-μs-laser pulses at 1064 nm with 33 to 73 J/cm2. Ns laser pulses can contact down to 1-μm-thick aluminum layers on silicon without inducing laser damage to the silicon and lead to sufficient strong mechanical contact. In case of μs laser pulses the limiting thickness is 2 μm.

  1. Quantification of a thermal damage threshold for astrocytes using infrared laser generated heat gradients.

    PubMed

    Liljemalm, Rickard; Nyberg, Tobias

    2014-04-01

    The response of cells and tissues to elevated temperatures is highly important in several research areas, especially in the area of infrared neural stimulation. So far, only the heat response of neurons has been considered. In this study, primary rat astrocytes were exposed to infrared laser pulses of various pulse lengths and the resulting cell morphology changes and cell migration was studied using light microscopy. By using a finite element model of the experimental setup the temperature distribution was simulated and the temperatures and times to induce morphological changes and migration were extracted. These threshold temperatures were used in the commonly used first-order reaction model according to Arrhenius to extract the kinetic parameters, i.e., the activation energy, E a, and the frequency factor, A c, for the system. A damage signal ratio threshold was defined and calculated to be 6% for the astrocytes to change morphology and start migrating.

  2. Laser treatments of deep-seated brain lesions

    NASA Astrophysics Data System (ADS)

    Ward, Helen A.

    1997-06-01

    The five year survival rate of deep-seated malignant brain tumors after surgery/radiotherapy is virtually 100 percent mortality. Special problems include: (1) Lesions often present late. (2) Position: lesion overlies vital structures, so complete surgical/radiotherapy lesion destruction can damage vital brain-stem functions. (3) Difficulty in differentiating normal brain form malignant lesions. This study aimed to use the unique properties of the laser: (a) to minimize damage during surgical removal of deep-seated brain lesions by operating via fine optic fibers; and (b) to employ the propensity of certain lasers for absorption of dyes and absorption and induction of fluorescence in some brain substances, to differentiate borders of malignant and normal brain, for more complete tumor removal. In the method a fine laser endoscopic technique was devised for removal of brain lesions. The results of this technique, were found to minimize and accurately predict the extent of thermal damage and shock waves to within 1-2mm of the surgical laser beam. Thereby it eliminated the 'popcorn' effect.

  3. A framework for quantifying and optimizing the value of seismic monitoring of infrastructure

    NASA Astrophysics Data System (ADS)

    Omenzetter, Piotr

    2017-04-01

    This paper outlines a framework for quantifying and optimizing the value of information from structural health monitoring (SHM) technology deployed on large infrastructure, which may sustain damage in a series of earthquakes (the main and the aftershocks). The evolution of the damage state of the infrastructure without or with SHM is presented as a time-dependent, stochastic, discrete-state, observable and controllable nonlinear dynamical system. The pre-posterior Bayesian analysis and the decision tree are used for quantifying and optimizing the value of SHM information. An optimality problem is then formulated how to decide on the adoption of SHM and how to manage optimally the usage and operations of the possibly damaged infrastructure and its repair schedule using the information from SHM. The objective function to minimize is the expected total cost or risk.

  4. Method for assaying clustered DNA damages

    DOEpatents

    Sutherland, Betsy M.

    2004-09-07

    Disclosed is a method for detecting and quantifying clustered damages in DNA. In this method, a first aliquot of the DNA to be tested for clustered damages with one or more lesion-specific cleaving reagents under conditions appropriate for cleavage of the DNA to produce single-strand nicks in the DNA at sites of damage lesions. The number average molecular length (Ln) of double stranded DNA is then quantitatively determined for the treated DNA. The number average molecular length (Ln) of double stranded DNA is also quantitatively determined for a second, untreated aliquot of the DNA. The frequency of clustered damages (.PHI..sub.c) in the DNA is then calculated.

  5. High-speed micro-scale laser shock peening using a fiber laser (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Zhang, Chenfei; Deng, Leimin; Sun, Shiding; Lu, Yongfeng

    2017-03-01

    Laser shock peening using low-energy nanosecond (ns) fiber lasers was investigated in this study to realize high-speed micro-scale laser shock peening on selected positions without causing surface damage. Due to the employment of a fiber laser with high-frequency and prominent environmental adaptability, the laser peening system is able to work with a much higher speed compared to traditional peening systems using Nd:YAG lasers and is promising for in-situ applications in harsh environments. Detailed surface morphology investigations both on sacrificial coatings and Al alloy surfaces after the fiber laser peening revealed the effects of focal position, pulse duration, peak power density, and impact times. Micro-dent arrays were also obtained with different spot-to-spot distances. Obvious micro-hardness improvement was observed inside the laser-peening-induced microdents after the fiber laser shock peening.

  6. Quantifying progression and regression of thrombotic risk in experimental atherosclerosis.

    PubMed

    Palekar, Rohun U; Jallouk, Andrew P; Goette, Matthew J; Chen, Junjie; Myerson, Jacob W; Allen, John S; Akk, Antonina; Yang, Lihua; Tu, Yizheng; Miller, Mark J; Pham, Christine T N; Wickline, Samuel A; Pan, Hua

    2015-07-01

    Currently, there are no generally applicable noninvasive methods for defining the relationship between atherosclerotic vascular damage and risk of focal thrombosis. Herein, we demonstrate methods to delineate the progression and regression of vascular damage in response to an atherogenic diet by quantifying the in vivo accumulation of semipermeable 200-300 nm perfluorocarbon core nanoparticles (PFC-NP) in ApoE null mouse plaques with [(19)F] magnetic resonance spectroscopy (MRS). Permeability to PFC-NP remained minimal until 12 weeks on diet, then increased rapidly following 12 weeks, but regressed to baseline within 8 weeks after diet normalization. Markedly accelerated clotting (53.3% decrease in clotting time) was observed in carotid artery preparations of fat-fed mice subjected to photochemical injury as defined by the time to flow cessation. For all mice on and off diet, an inverse linear relationship was observed between the permeability to PFC-NP and accelerated thrombosis (P = 0.02). Translational feasibility for quantifying plaque permeability and vascular damage in vivo was demonstrated with clinical 3 T MRI of PFC-NP accumulating in plaques of atherosclerotic rabbits. These observations suggest that excessive permeability to PFC-NP may indicate prothrombotic risk in damaged atherosclerotic vasculature, which resolves within weeks after dietary therapy. © FASEB.

  7. Numerical simulation of temperature field in K9 glass irradiated by ultraviolet pulse laser

    NASA Astrophysics Data System (ADS)

    Wang, Xi; Fang, Xiaodong

    2015-10-01

    The optical component of photoelectric system was easy to be damaged by irradiation of high power pulse laser, so the effect of high power pulse laser irradiation on K9 glass was researched. A thermodynamic model of K9 glass irradiated by ultraviolet pulse laser was established using the finite element software ANSYS. The article analyzed some key problems in simulation process of ultraviolet pulse laser damage of K9 glass based on ANSYS from the finite element models foundation, meshing, loading of pulse laser, setting initial conditions and boundary conditions and setting the thermal physical parameters of material. The finite element method (FEM) model was established and a numerical analysis was performed to calculate temperature field in K9 glass irradiated by ultraviolet pulse laser. The simulation results showed that the temperature of irradiation area exceeded the melting point of K9 glass, while the incident laser energy was low. The thermal damage dominated in the damage mechanism of K9 glass, the melting phenomenon should be much more distinct.

  8. The role of film interfaces in near-ultraviolet absorption and pulsed-laser damage in ion-beam-sputtered coatings based on HfO 2/SiO 2 thin-film pairs

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ristau, Detlev; Papernov, S.; Kozlov, A. A.

    2015-11-23

    The role of thin-film interfaces in the near-ultraviolet absorption and pulsed-laser–induced damage was studied for ion-beam–sputtered and electron-beam–evaporated coatings comprised from HfO 2 and SiO 2 thin-film pairs. To separate contributions from the bulk of the film and from interfacial areas, absorption and damage-threshold measurements were performed for a one-wave (355-nm wavelength) thick, HfO 2 single-layer film and for a film containing seven narrow HfO 2 layers separated by SiO 2 layers. The seven-layer film was designed to have a total optical thickness of HfO 2 layers, equal to one wave at 355 nm and an E-field peak and averagemore » intensity similar to a single-layer HfO 2 film. Absorption in both types of films was measured using laser calorimetry and photothermal heterodyne imaging. The results showed a small contribution to total absorption from thin-film interfaces, as compared to HfO 2 film material. The relevance of obtained absorption data to coating near-ultraviolet, nanosecond-pulse laser damage was verified by measuring the damage threshold and characterizing damage morphology. The results of this study revealed a higher damage resistance in the seven-layer coating as compared to the single-layer HfO 2 film in both sputtered and evaporated coatings. Here, the results are explained through the similarity of interfacial film structure with structure formed during the co-deposition of HfO 2 and SiO 2 materials.« less

  9. [A Method Research on Environmental Damage Assessment of a Truck Rollover Pollution Incident].

    PubMed

    Cai, Feng; Zhao, Shi-ho; Chen, Gang-cai; Xian, Si-shu; Yang, Qing-ling; Zhou, Xian-jie; Yu, Hai

    2015-05-01

    With high occurrence of sudden water pollution incident, China faces an increasingly severe situation of water environment. In order to deter the acts of environmental pollution, ensure the damaged resources of environment can be restored and compensated, it is very critical to quantify the economic losses caused by the sudden water pollution incident. This paper took truck rollover pollution incidents in Chongqing for an example, established a set of evaluation method for quantifying the environmental damage, and then assessed the environmental damage by the method from four aspects, including the property damage, ecological environment and resources damages, the costs of administrative affairs in emergency disposal, and the costs of investigation and evaluation.

  10. Ultraviolet Laser-induced ignition of RDX single crystal

    PubMed Central

    Yan, Zhonghua; Zhang, Chuanchao; Liu, Wei; Li, Jinshan; Huang, Ming; Wang, Xuming; Zhou, Guorui; Tan, Bisheng; Yang, Zongwei; Li, Zhijie; Li, Li; Yan, Hongwei; Yuan, Xiaodong; Zu, Xiaotao

    2016-01-01

    The RDX single crystals are ignited by ultraviolet laser (355 nm, 6.4 ns) pulses. The laser-induced damage morphology consisted of two distinct regions: a core region of layered fracture and a peripheral region of stripped material surrounding the core. As laser fluence increases, the area of the whole crack region increases all the way, while both the area and depth of the core region increase firstly, and then stay stable over the laser fluence of 12 J/cm2. The experimental details indicate the dynamics during laser ignition process. Plasma fireball of high temperature and pressure occurs firstly, followed by the micro-explosions on the (210) surface, and finally shock waves propagate through the materials to further strip materials outside and yield in-depth cracks in larger surrounding region. The plasma fireball evolves from isotropic to anisotropic under higher laser fluence resulting in the damage expansion only in lateral direction while maintaining the fixed depth. The primary insights into the interaction dynamics between laser and energetic materials can help developing the superior laser ignition technique. PMID:26847854

  11. Pulmonary resections: cytostructural effects of different-wavelength lasers versus electrocautery.

    PubMed

    Scanagatta, Paolo; Pelosi, Giuseppe; Leo, Francesco; Furia, Simone; Duranti, Leonardo; Fabbri, Alessandra; Manfrini, Aldo; Villa, Antonello; Vergani, Barbara; Pastorino, Ugo

    2012-01-01

    There are few papers on the cytostructural effects of surgical instruments used during pulmonary resections. The aim of the present study was to evaluate the parenchymal damage caused by different surgical instruments: a new generation electrosurgical scalpel and two different-wavelength lasers. Six surgical procedures of pulmonary resection for nodules were performed using a new generation electrosurgical scalpel, a 1318 nm neodymium (Nd:YAG) laser or a 2010 nm thulium laser (two procedures for each instrument). Specimens were analyzed using optical microscopy and scansion electronic microscopy. Severe cytostructural damage was found to be present in an average of 1.25 mm in depth from the cutting surface in the patients treated using electrosurgical cautery. The depth of this zone dropped to less than 1 mm in patients treated by laser, being as small as 0.2 mm using the laser with a 2010 nm-wavelength and 0.6 mm with the 1318 nm-wavelength laser. These preliminary findings support the use of laser to perform conservative pulmonary resections (i.e., metastasectomies), since it is more likely to avoid damage to surrounding structures. Controlled randomized trials are needed to support the clinical usefulness and feasibility of new types of lasers for pulmonary resections.

  12. Strength and failure of a damaged material

    DOE PAGES

    Cerreta, Ellen K.; Gray III, George T.; Trujillo, Carl P.; ...

    2015-09-07

    Under complex, dynamic loading conditions, damage can occur within a material. Should this damage not lead to catastrophic failure, the material can continue to sustain further loading. But, little is understood about how to represent the mechanical response of a material that has experienced dynamic loading leading to incipient damage. We examine this effect in copper. Copper is shock loaded to impart an incipient state of damage to the material. Thereafter compression and tensile specimens were sectioned from the dynamically damaged specimen to quantify the subsequent properties of the material in the region of intense incipient damage and in regionsmore » far from the damage. Finally, we observed that enhanced yield stresses result from the damaged material even over material, which has simply been shock loaded and not damaged. These results are rationalized in terms of stored plastic work due to the damage process.« less

  13. Strength and failure of a damaged material

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cerreta, Ellen K.; Gray III, George T.; Trujillo, Carl P.

    Under complex, dynamic loading conditions, damage can occur within a material. Should this damage not lead to catastrophic failure, the material can continue to sustain further loading. But, little is understood about how to represent the mechanical response of a material that has experienced dynamic loading leading to incipient damage. We examine this effect in copper. Copper is shock loaded to impart an incipient state of damage to the material. Thereafter compression and tensile specimens were sectioned from the dynamically damaged specimen to quantify the subsequent properties of the material in the region of intense incipient damage and in regionsmore » far from the damage. Finally, we observed that enhanced yield stresses result from the damaged material even over material, which has simply been shock loaded and not damaged. These results are rationalized in terms of stored plastic work due to the damage process.« less

  14. Application of a flexible CO(2) laser fiber for neurosurgery: laser-tissue interactions.

    PubMed

    Ryan, Robert W; Wolf, Tamir; Spetzler, Robert F; Coons, Stephen W; Fink, Yoel; Preul, Mark C

    2010-02-01

    The CO(2) laser has an excellent profile for use in neurosurgery. Its high absorption in water results in low thermal spread, sparing adjacent tissue. Use of this laser has been limited to line-of-sight applications because no solid fiber optic cables could transmit its wavelength. Flexible photonic bandgap fiber technology enables delivery of CO(2) laser energy through a flexible fiber easily manipulated in a handheld device. The authors examined and compared the first use of this CO(2) laser fiber to conventional methods for incising neural tissue. Carbon dioxide laser energy was delivered in pulsed or continuous wave settings for different power settings, exposure times, and distances to cortical tissue of 6 anesthetized swine. Effects of CO(2) energy on the tissue were compared with bipolar cautery using a standard pial incision technique, and with scalpel incisions without cautery. Tissue was processed for histological analysis (using H & E, silver staining, and glial fibrillary acidic protein immunohistochemistry) and scanning electron microscopy, and lesion measurements were made. Light microscopy and scanning electron microscopy revealed laser incisions of consistent shape, with central craters surrounded by limited zones of desiccated and edematous tissue. Increased laser power resulted in deeper but not significantly wider incisions. Bipolar cautery lesions showed desiccated and edematous zones but did not incise the pia, and width increased more than depth with higher power. Incisions made without using cautery produced hemorrhage but minimal adjacent tissue damage. The photonic bandgap fiber CO(2) laser produced reliable cortical incisions, adjustable over a range of settings, with minimal adjacent thermal tissue damage. Ease of application under the microscope suggests this laser system has reached true practicality for neurosurgery.

  15. Precise femtosecond laser ablation of dental hard tissue: preliminary investigation on adequate laser parameters

    NASA Astrophysics Data System (ADS)

    Hikov, Todor; Pecheva, Emilia; Montgomery, Paul; Antoni, Frederic; Leong-Hoi, Audrey; Petrov, Todor

    2017-01-01

    This work aims at evaluating the possibility of introducing state-of-the-art commercial femtosecond laser system in restorative dentistry by maintaining well-known benefits of lasers for caries removal, but also in overcoming disadvantages such as thermal damage of irradiated substrate. Femtosecond ablation of dental hard tissue is investigated by changing the irradiation parameters (pulsed laser energy, scanning speed and pulse repetition rate), assessed for enamel and dentin. The femtosecond laser system used in this work may be suitable for cavity preparation in dentin and enamel, due to the expected effective ablation and low temperature increase when using ultra short laser pulses. If adequate laser parameters are selected, this system seems to be promising for promoting a laser-assisted, minimally invasive approach in restorative dentistry.

  16. Pilot study about dose-effect relationship of ocular injury in argon laser photocoagulation

    NASA Astrophysics Data System (ADS)

    Chen, P.; Zhang, C. P.; Fu, X. B.; Zhang, T. M.; Wang, C. Z.; Qian, H. W.; San, Q.

    2011-03-01

    The aim of this article was to study the injury effect of either convergent or parallel argon laser beam on rabbit retina, get the dose-effect relationship for the two types of laser beams, and calculate the damage threshold of argon laser for human retinas. An argon laser therapeutic instrument for ophthalmology was used in this study. A total of 80 rabbit eyes were irradiated for 600 lesions, half of which were treated by convergent laser and the other half were done with parallel laser beam. After irradiation, slit lamp microscope and fundus photography were used to observe the lesions, change and the incidence of injury was processed statistically to get the damage threshold of rabbit retina. Based on results from the experiments on animals and the data from clinical cases of laser treatment, the photocoagulation damage thresholds of human retinas for convergent and parallel argon laser were calculated to be 0.464 and 0.285 mJ respectively. These data provided biological reference for safely operation when employing laser photocoagulation in clinical practice and other fields.

  17. Quantifying the Thermal Fatigue of CPV Modules

    NASA Astrophysics Data System (ADS)

    Bosco, Nick; Kurtz, Sarah

    2010-10-01

    A method is presented to quantify thermal fatigue in the CPV die-attach from meteorological data. A comparative study between cities demonstrates a significant difference in the accumulated damage. These differences are most sensitive to the number of larger (ΔT) thermal cycles experienced for a location. High frequency data (<1/min) may be required to most accurately employ this method.

  18. Thermal damage study of beryllium windows used as vacuum barriers in synchrotron radiation beamlines

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Holdener, F.R.; Johnson, G.L.; Karpenko, V.P.

    An experimental study to investigate thermal-induced damage to SSRL-designed beryllium foil windows was performed at LLNL's Laser Welding Research Facility. The primary goal of this study was to determine the threshold at which thermal-stress-induced damage occurs in these commonly used vacuum barriers. An Nd:Yag pulsed laser with cylindrical optics and a carefully designed test cell provided a test environment that closely resembles the actual beamline conditions at SSRL. Tests performed on two beryllium window geometries, with different vertical aperture dimensions but equal foil thicknesses of 0.254 mm, resulted in two focused total-power thresholds at which incipient damage was determined. Formore » a beam spot size similar to that of the Beamline-X Wiggler Line, onset of surface damage for a 5-mm by 25-mm aperture window was observed at 170 W after 174,000 laser pulses (1.2-ms pulse at 100 pps). A second window with double the vertical aperture dimension (10 mm by 25 mm) was observed to have surface cracking after 180,000 laser pulses with 85 W impinging its front surface. It failed after approximately 1,000,000 pulses. Another window of the same type (10 mm by 25 mm) received 2,160,000 laser pulses at 74.4 W, and subsequent metallographic sectioning revealed no signs of through-thickness damage. Comparison of windows with equal foil thicknesses and aperture dimensions has effectively identified the heat flux limit for incipient failure. The data show that halving the aperture's vertical dimension allows doubling the total incident power for equivalent onsets of thermal-induced damage.« less

  19. Outstanding laser damage threshold in Li2MnGeS4 and tunable optical nonlinearity in diamond-like semiconductors.

    PubMed

    Brant, Jacilynn A; Clark, Daniel J; Kim, Yong Soo; Jang, Joon I; Weiland, Ashley; Aitken, Jennifer A

    2015-03-16

    The new Li2MnGeS4 and Li2CoSnS4 compounds result from employing a rational and simple design strategy that guides the discovery of diamond-like semiconductors (DLSs) with wide regions of optical transparency, high laser damage threshold, and efficient second-order optical nonlinearity. Single-crystal X-ray diffraction was used to solve and refine the crystal structures of Li2MnGeS4 and Li2CoSnS4, which crystallize in the noncentrosymmetric space groups Pna21 and Pn, respectively. Synchrotron X-ray powder diffraction (SXRPD) was used to assess the phase purity, and diffuse reflectance UV-vis-NIR spectroscopy was used to estimate the bandgaps of Li2MnGeS4 (Eg = 3.069(3) eV) and Li2CoSnS4 (Eg = 2.421(3) eV). In comparison with Li2FeGeS4, Li2FeSnS4, and Li2CoSnS4 DLSs, Li2MnGeS4 exhibits the widest region of optical transparency (0.60-25 μm) and phase matchability (≥1.6 μm). All four of the DLSs exhibit second-harmonic generation and are compared with the benchmark NLO material, AgGaSe2. Most remarkably, Li2MnGeS4 does not undergo two- or three-photon absorption upon exposure to a fundamental Nd:YAG beam (λ = 1.064 μm) and exhibits a laser damage threshold > 16 GW/cm(2).

  20. Retinotomy using an erbium:YAG laser on human autopsy eyes

    NASA Astrophysics Data System (ADS)

    Ellsworth, Lansing G.; Kramer, Theresa R.; Noecker, Robert J.; Snyder, Robert W.; Yarborough, J. Michael

    1994-06-01

    Mid-IR lasers that operate near the absorption peak of water have a short penetration depth in ocular tissues. Ablation of tissue can be accomplished with minimal coagulative damage to underlying structures. We used an erbium:YAG laser equipped with a contact probe to create retinotomy sites in the human retina of eye bank eyes. An erbium:YAG laser (2.94 micrometers ) equipped with an infrared transmitting glass fiber and a sapphire tip (400 micrometers ) was used to directly ablate the surface of the retina. We administered both single and multiple pulses to the macula and peripheral retina using energy levels from 4 to 16 mJ per pulse. The retinas were then examined histopathologically to evaluate the extent of ablation and coagulative damage. Single pulses at low energy levels were noted to cause ablative damage to the nerve fiber layer and ganglion cell layer without a notable coagulative effect. The mean ablation depth at lower energy levels was less than the mean ablation depth at higher energy levels. Extensive laser application produced disruption of the retinal pigment epithelium, choroid and sclera. the erbium:YAG laser equipped with a contact probe is an effective means of creating retinotomies in human autopsy eyes. When used in the single pulse mode at lower energy levels, the erbium:YAG laser appears capable of removing superficial retinal layers without damaging deeper structures.

  1. Phagocytic response of astrocytes to damaged neighboring cells

    PubMed Central

    Cruz, Gladys Mae S.; Ro, Clarissa C.; Moncada, Emmanuel G.; Khatibzadeh, Nima; Flanagan, Lisa A.; Berns, Michael W.

    2018-01-01

    This study aims to understand the phagocytic response of astrocytes to the injury of neurons or other astrocytes at the single cell level. Laser nanosurgery was used to damage individual cells in both primary mouse cortical astrocytes and an established astrocyte cell line. In both cases, the release of material/substances from laser-irradiated astrocytes or neurons induced a phagocytic response in near-by astrocytes. Propidium iodide stained DNA originating from irradiated cells was visible in vesicles of neighboring cells, confirming phagocytosis of material from damaged cortical cells. In the presence of an intracellular pH indicator dye, newly formed vesicles correspond to acidic pH fluorescence, thus suggesting lysosome bound degradation of cellular debris. Cells with shared membrane connections prior to laser damage had a significantly higher frequency of induced phagocytosis compared to isolated cells with no shared membrane. The increase in phagocytic response of cells with a shared membrane occurred regardless of the extent of shared membrane (a thin filopodial connection vs. a cell cluster with significant shared membrane). In addition to the presence (or lack) of a membrane connection, variation in phagocytic ability was also observed with differences in injury location within the cell and distance separating isolated astrocytes. These results demonstrate the ability of an astrocyte to respond to the damage of a single cell, be it another astrocyte, or a neuron. This single-cell level of analysis results in a better understanding of the role of astrocytes to maintain homeostasis in the CNS, particularly in the sensing and removal of debris in damaged or pathologic nervous tissue. PMID:29708987

  2. Laser vaccine adjuvants

    PubMed Central

    Kashiwagi, Satoshi; Brauns, Timothy; Gelfand, Jeffrey; Poznansky, Mark C

    2014-01-01

    Immunologic adjuvants are essential for current vaccines to maximize their efficacy. Unfortunately, few have been found to be sufficiently effective and safe for regulatory authorities to permit their use in vaccines for humans and none have been approved for use with intradermal vaccines. The development of new adjuvants with the potential to be both efficacious and safe constitutes a significant need in modern vaccine practice. The use of non-damaging laser light represents a markedly different approach to enhancing immune responses to a vaccine antigen, particularly with intradermal vaccination. This approach, which was initially explored in Russia and further developed in the US, appears to significantly improve responses to both prophylactic and therapeutic vaccines administered to the laser-exposed tissue, particularly the skin. Although different types of lasers have been used for this purpose and the precise molecular mechanism(s) of action remain unknown, several approaches appear to modulate dendritic cell trafficking and/or activation at the irradiation site via the release of specific signaling molecules from epithelial cells. The most recent study, performed by the authors of this review, utilized a continuous wave near-infrared laser that may open the path for the development of a safe, effective, low-cost, simple-to-use laser vaccine adjuvant that could be used in lieu of conventional adjuvants, particularly with intradermal vaccines. In this review, we summarize the initial Russian studies that have given rise to this approach and comment upon recent advances in the use of non-tissue damaging lasers as novel physical adjuvants for vaccines. PMID:25424797

  3. Cutaneous applications of lasers.

    PubMed

    Ries, W R; Speyer, M T

    1996-12-01

    The cutaneous application of lasers today includes more selective and less damaging devices. Carbon dioxide, neodymium:yttrium-aluminum-garnet, potassium titanyl phosphate, argon, and yellow lasers are most prevalent in treating cutaneous lesions. Specific techniques in skin resurfacing, keloid excision, rhinophyma, actinic cheilitis ablation, and excision of superficial cutaneous tumors are discussed. Proper management of cutaneous vascular lesions is also presented.

  4. Mitochondrial dependent oxidative stress in cell culture induced by laser radiation at 1265 nm.

    PubMed

    Saenko, Yury V; Glushchenko, Eugenia S; Zolotovskii, Igor O; Sholokhov, Evgeny; Kurkov, Andrey

    2016-04-01

    Photodynamic therapy is the main technique applied for surface carcinoma treatment. This technique employs singlet oxygen generated via a laser excited photosensitizer as a main damaging agent. However, prolonged sensitivity to intensive light, relatively low tissue penetration by activating light the cost of photosensitizer (PS) administration can limit photodynamic therapy applications. Early was reported singlet oxygen generation without photosensitizer induced by a laser irradiation at the wavelength of 1250-1270 nm. Here, we study the dynamics of oxidative stress, DNA damage, changes of mitochondrial potential, and mitochondrial mass induced by a laser at 1265 nm have been studied in HCT-116 and CHO-K cells. Laser irradiation of HCT-116 and CHO-K cells has induced a dose-dependent cell death via increasing intracellular reactive oxygen species (ROS) concentration, increase of DNA damage, decrease of mitochondrial potential, and reduced glutathione. It has been shown that, along with singlet oxygen generation, the increase of the intracellular ROS concentration induced by mitochondrial damage contributes to the damaging effect of the laser irradiation at 1265 nm.

  5. High power lasers: Sources, laser-material interactions, high excitations, and fast dynamics in laser processing and industrial applications; Proceedings of the Meeting, The Hague, Netherlands, Mar. 31-Apr. 3, 1987

    NASA Technical Reports Server (NTRS)

    Kreutz, E. W. (Editor); Quenzer, Alain (Editor); Schuoecker, Dieter (Editor)

    1987-01-01

    The design and operation of high-power lasers for industrial applications are discussed in reviews and reports. Topics addressed include the status of optical technology in the Netherlands, laser design, the deposition of optical energy, laser diagnostics, nonmetal processing, and energy coupling and plasma formation. Consideration is given to laser-induced damage to materials, fluid and gas flow dynamics, metal processing, and manufacturing. Graphs, diagrams, micrographs, and photographs are provided.

  6. Safety of cornea and iris in ocular surgery with 355-nm lasers.

    PubMed

    Wang, Jenny; Chung, Jae Lim; Schuele, Georg; Vankov, Alexander; Dalal, Roopa; Wiltberger, Michael; Palanker, Daniel

    2015-09-01

    A recent study showed that 355-nm nanosecond lasers cut cornea with similar precision to infrared femtosecond lasers. However, use of ultraviolet wavelength requires precise assessment of ocular safety to determine the range of possible ophthalmic applications. In this study, the 355-nm nanosecond laser was evaluated for corneal and iris damage in rabbit, porcine, and human donor eyes as determined by minimum visible lesion (MVL) observation, live/dead staining of the endothelium, and apoptosis assay. Single-pulse damage to the iris was evaluated on porcine eyes using live/dead staining. In live rabbits, the cumulative median effective dose (ED50) for corneal damage was 231 J/cm2, as seen by lesion observation. Appearance of endothelial damage in live/dead staining or apoptosis occurred at higher radiant exposure of 287 J/cm2. On enucleated rabbit and porcine corneas, ED50 was 87 and 52 J/cm2, respectively, by MVL, and 241 and 160 J/cm2 for endothelial damage. In human eyes, ED50 for MVL was 110 J/cm2 and endothelial damage at 453 J/cm2. Single-pulse iris damage occurred at ED 50 of 208 mJ/cm2. These values determine the energy permitted for surgical patterns and can guide development of ophthalmic laser systems. Lower damage threshold in corneas of enucleated eyes versus live rabbits is noted for future safety evaluation.

  7. Laser effects based optimal laser parameter identifications for paint removal from metal substrate at 1064 nm: a multi-pulse model

    NASA Astrophysics Data System (ADS)

    Han, Jinghua; Cui, Xudong; Wang, Sha; Feng, Guoying; Deng, Guoliang; Hu, Ruifeng

    2017-10-01

    Paint removal by laser ablation is favoured among cleaning techniques due to its high efficiency. How to predict the optimal laser parameters without producing damage to substrate still remains challenging for accurate paint stripping. On the basis of ablation morphologies and combining experiments with numerical modelling, the underlying mechanisms and the optimal conditions for paint removal by laser ablation are thoroughly investigated. Our studies suggest that laser paint removal is dominated by the laser vaporization effect, thermal stress effect and laser plasma effect, in which thermal stress effect is the most favoured while laser plasma effect should be avoided during removal operations. Based on the thermodynamic equations, we numerically evaluated the spatial distribution of the temperature as well as thermal stress in the paint and substrate under the irradiation of laser pulse at 1064 nm. The obtained curves of the paint thickness vs. threshold fluences can provide the reference standard of laser parameter selection in view of the paint layer with different thickness. A multi-pulse model is proposed and validated under a constant laser fluence to perfectly remove a thicker paint layer. The investigations and the methods proposed here might give hints to the efficient operations on the paint removal and lowering the risk of substrate damages.

  8. Diode Lasers used in Plastic Welding and Selective Laser Soldering - Applications and Products

    NASA Astrophysics Data System (ADS)

    Reinl, S.

    Aside from conventional welding methods, laser welding of plastics has established itself as a proven bonding method. The component-conserving and clean process offers numerous advantages and enables welding of sensitive assemblies in automotive, electronic, medical, human care, food packaging and consumer electronics markets. Diode lasers are established since years within plastic welding applications. Also, soft soldering using laser radiation is becoming more and more significant in the field of direct diode laser applications. Fast power controllability combined with a contactless temperature measurement to minimize thermal damage make the diode laser an ideal tool for this application. These advantages come in to full effect when soldering of increasingly small parts in temperature sensitive environments is necessary.

  9. Optical damage performance of conductive widegap semiconductors: spatial, temporal, and lifetime modeling

    DOE PAGES

    Elhadj, Selim; Yoo, Jae-hyuck; Negres, Raluca A.; ...

    2016-12-19

    The optical damage performance of electrically conductive gallium nitride (GaN) and indium tin oxide (ITO) films is addressed using large area, high power laser beam exposures at 1064 nm sub-bandgap wavelength. Analysis of the laser damage process assumes that onset of damage (threshold) is determined by the absorption and heating of a nanoscale region of a characteristic size reaching a critical temperature. We use this model to rationalize semi-quantitatively the pulse width scaling of the damage threshold from picosecond to nanosecond timescales, along with the pulse width dependence of the damage threshold probability derived by fitting large beam damage densitymore » data. Multi-shot exposures were used to address lifetime performance degradation described by an empirical expression based on the single exposure damage model. A damage threshold degradation of at least 50% was observed for both materials. Overall, the GaN films tested had 5-10 × higher optical damage thresholds than the ITO films tested for comparable transmission and electrical conductivity. This route to optically robust, large aperture transparent electrodes and power optoelectronics may thus involve use of next generation widegap semiconductors such as GaN.« less

  10. Assessment of damage in 'green' composites

    NASA Astrophysics Data System (ADS)

    Malinowski, Paweł H.; Ostachowicz, Wiesław M.; Touchard, Fabienne; Boustie, Michel; Chocinski-Arnault, Laurence; Pascual Gonzalez, Pedro; Berthe, Laurent; de Vasconcellos, Davi; Sorrentino, Luigi

    2017-04-01

    The behaviour of eco-composites, when subjected to laser or mechanical impact loadings, is not well known yet. A research was proposed looking at the behaviour of `green' and synthetic composites under impact loading. The study was focused on composites reinforced with short, medium and long fibres. Short fibre composites were made of spruce fibres and ABS. The fibres were used both as received and after a thermal treatment. Another set of samples was made of 60 mm-long flax fibres. Two types of thermoplastic polymers were used as matrices: polypropylene and polylactide. Also a woven eco-composite was investigated. It was made of plain woven hemp fabric impregnated with epoxy resin. A fully synthetic woven composite, used as reference laminate for comparison with `green' composites, was prepared by using a plain weave woven glass fabric impregnated with epoxy resin. Mechanical impacts were performed by means of a falling dart impact testing machine. The specimens were tested at different impact energy levels (from 1J to 5J) by keeping constant the mass of the impactor and varying the drop height. Laser impact tests were performed by means of a high power laser shock facility. All the samples were tested at six different laser shock intensities, keeping constant the shock diameter and the pulse duration. Six assessment techniques were employed in order to analyse and compare impact damages: eye observation, back face relief, terahertz spectroscopy, laser vibrometry, X-ray micro-tomography and microscopic observations. Different damage detection thresholds for each material and technique were obtained.

  11. Optical components damage parameters database system

    NASA Astrophysics Data System (ADS)

    Tao, Yizheng; Li, Xinglan; Jin, Yuquan; Xie, Dongmei; Tang, Dingyong

    2012-10-01

    Optical component is the key to large-scale laser device developed by one of its load capacity is directly related to the device output capacity indicators, load capacity depends on many factors. Through the optical components will damage parameters database load capacity factors of various digital, information technology, for the load capacity of optical components to provide a scientific basis for data support; use of business processes and model-driven approach, the establishment of component damage parameter information model and database systems, system application results that meet the injury test optical components business processes and data management requirements of damage parameters, component parameters of flexible, configurable system is simple, easy to use, improve the efficiency of the optical component damage test.

  12. [Progress in laser neurosurgery].

    PubMed

    Majchrzak, H; Kopera, M; Idzik, M

    1991-01-01

    Nd:YAG lasers with different wavelengths are used in neurosurgery. Their great advantage is the ability of coagulation of blood vessels and delivery through flexible fiber optics . Nd:YAG laser with wavelength 1.318 microns is used, besides, to connect blood vessels and nerves. CO2 laser is the best cutting tool but requires, for delivery rigid cable. Both types of lasers cause shrinkage and vaporisation of the tumors what facilitates its removing without greater traumatisation of surrounding tissues. The introduction of sapphire contact tips to Nd:YAG and argon lasers enables application of small laser powers and diminish the area of damage in surrounding structures. Contact laser is used for destroying of tumours, coagulation of blood vessels, restoration of patency of the main arteries, interstitial denaturation of gliomas and denaturation of the nucleus pulposus in lumbar vertebral column.

  13. Prevention of CO2 laser-induced endotracheal tube fires with the laser-guard protective coating.

    PubMed

    Sosis, M B; Dillon, F

    1992-01-01

    To determine how well Laser-Guard protects polyvinyl chloride (PVC) endotracheal tubes from the carbon dioxide (CO2) laser. Bare and Laser-Guard-protected PVC endotracheal tubes were tested with 5 L/min of oxygen (O2) passing through them. Research laboratory of a university-affiliated metropolitan medical center. After moistening the Laser-Guard-protected endotracheal tubes, we subjected the tubes to CO2 laser radiation at 10 and 70 watts until combustion occurred or 60 seconds had elapsed. The bare PVC tube ignited and a "blowtorch" fire occurred after 3 seconds of CO2 laser use at 70 watts. The moistened Laser-Guard-protected PVC endotracheal tubes were not significantly damaged by 1 minute of laser use at 70 watts. Laser-Guard protects the shafts of combustible PVC endotracheal tubes from direct, high-power, continuous CO2 laser radiation.

  14. Cornea surgery with nanojoule femtosecond laser pulses

    NASA Astrophysics Data System (ADS)

    Koenig, Karsten; Wang, Bagui; Riemann, Iris; Kobow, Jens

    2005-04-01

    We report on a novel optical method for (i) flap-generation in LASIK procedures as well as (ii) for flap-free intrastromal refractive surgery based on nanojoule femtosecond laser pulses. The near infrared 200 fs pulses for multiphoton ablation have been provided by ultracompact turn-key MHz laser resonators. LASIK flaps and intracorneal cavities have been realized with high precision within living New Zealand rabbits using the system FemtoCutO (JenLab GmbH, Jena, Germany) at 800 nm laser wavelength. Using low-energy sub-2 nJ laser pulses, collateral damage due to photodisruptive and self-focusing effects was avoided. The laser ablation system consists of fast galvoscanners, focusing optics of high numerical aperture as well as a sensitive imaging system and provides also the possibility of 3D multiphoton imaging of fluorescent cellular organelles and SHG signals from collagen. Multiphoton tomography of the cornea was used to determine the exact intratissue beam position and to visualize intraocular post-laser effects. The wound healing process has been investigated up to 90 days after instrastromal laser ablation by histological analysis. Regeneration of damaged collagen structures and the migration of inflammation cells have been detected.

  15. The effect of laser ablation parameters on optical limiting properties of silver nanoparticles

    NASA Astrophysics Data System (ADS)

    Gursoy, Irmak; Yaglioglu, Halime Gul

    2017-09-01

    This paper presents the effect of laser ablation parameters on optical limiting properties of silver nanoparticles. The current applications of lasers such as range finding, guidance, detection, illumination and designation have increased the potential of damaging optical imaging systems or eyes temporary or permanently. The applications of lasers introduce risks for sensors or eyes, when laser power is higher than damage threshold of the detection system. There are some ways to protect these systems such as neutral density (nd) filters, shutters, etc. However, these limiters reduce the total amount of light that gets into the system. Also, response time of these limiters may not be fast enough to prevent damage and cause precipitation in performance due to deprivation of transmission or contrast. Therefore, optical limiting filters are needed that is transparent for low laser intensities and limit or block the high laser intensities. Metal nanoparticles are good candidates for such optical limiting filters for ns pulsed lasers or CW lasers due to their high damage thresholds. In this study we investigated the optical limiting performances of silver nanoparticles produced by laser ablation technique. A high purity silver target immersed in pure water was ablated with a Nd:YAG nanosecond laser at 532 nm. The effect of altering laser power and ablation time on laser ablation efficiency of nanoparticles was investigated experimentally and optimum values were specified. Open aperture Zscan experiment was used to investigate the effect of laser ablation parameters on the optical limiting performances of silver nanoparticles in pure water. It was found that longer ablation time decreases the optical limiting threshold. These results are useful for silver nanoparticles solutions to obtain high performance optical limiters.

  16. Laser radiation bracket debonding

    NASA Astrophysics Data System (ADS)

    Dostálová, Tat'jana; Jelínková, Helena; Šulc, Jan; Koranda, Petr; Nemec, Michal; Racek, Jaroslav; Miyagi, Mitsunobu

    2008-02-01

    Ceramic brackets are an aesthetic substitute for conventional stainless steel brackets in orthodontic patients. However, ceramic brackets are more brittle and have higher bond strengths, which can lead to bracket breakage and enamel damage during classical type of debonding. This study examined the possibility of laser radiation ceramic brackets removing as well as the possible damage of a surface structure of hard dental tissue after this procedure. Two types of lasers were used for the experiments - a laser diode LIMO HLU20F400 generating a wavelength of 808 nm with the maximum output power 20W at the end of the fiber (core diameter 400 μm, numerical aperture 0.22). As a second source, a diode-pumped Tm:YAP laser system generating a wavelength of 1.9 μm, with up to 3.8 W maximum output power was chosen. For the investigation, extracted incisors with ceramic brackets were used. In both cases, laser radiation was applied for 0.5 minute at a maximum power of 1 W. Temperature changes of the irradiated tissue was registered by camera Electrophysics PV320. After the interaction experiment, the photo-documentation was prepared by the stereomicroscope Nikon SMZ 2T, Japan. The surface tissue analysis was processed in "low vacuum" (30 Pa) regime without desiccation. This technique was used to record back-scattered electron images. Selecting the appropriate laser, resin, and bracket combination can minimize risks of enamel degradation and make debonding more safe.

  17. Adaptive laser conditioning of reflective thin film based on photo thermal lens probe

    NASA Astrophysics Data System (ADS)

    Liu, Zhichao; Zheng, Yi; Zhang, Qinghua; Pan, Feng; Wei, Yaowei; Wang, Jian; Xu, Qiao

    2017-12-01

    A novel laser conditioning (LC) concept that performs adaptive control of exposure fluence is proposed. As photo-thermal absorption effect can discover defects responsible for laser-induced damage of reflective thin film, in situ photo-thermal lens probe is introduced in conventional LC procedure to detect defects during raster-scanning. The absorptance signal is fed back to guide the adaptive control of exposure fluence. By this method, the damage risk accompanying with LC can be reduced to a rather low level. In order to test the performance of adaptive laser conditioning (ALC), an experimental setup has been built, and several film samples have been tested. The results show that ALC is effective at reducing laser damage risk.

  18. Damage Detection Using Holography and Interferometry

    NASA Technical Reports Server (NTRS)

    Decker, Arthur J.

    2003-01-01

    This paper reviews classical approaches to damage detection using laser holography and interferometry. The paper then details the modern uses of electronic holography and neural-net-processed characteristic patterns to detect structural damage. The design of the neural networks and the preparation of the training sets are discussed. The use of a technique to optimize the training sets, called folding, is explained. Then a training procedure is detailed that uses the holography-measured vibration modes of the undamaged structures to impart damage-detection sensitivity to the neural networks. The inspections of an optical strain gauge mounting plate and an International Space Station cold plate are presented as examples.

  19. Target isolation system, high power laser and laser peening method and system using same

    DOEpatents

    Dane, C. Brent; Hackel, Lloyd A.; Harris, Fritz

    2007-11-06

    A system for applying a laser beam to work pieces, includes a laser system producing a high power output beam. Target delivery optics are arranged to deliver the output beam to a target work piece. A relay telescope having a telescope focal point is placed in the beam path between the laser system and the target delivery optics. The relay telescope relays an image between an image location near the output of the laser system and an image location near the target delivery optics. A baffle is placed at the telescope focal point between the target delivery optics and the laser system to block reflections from the target in the target delivery optics from returning to the laser system and causing damage.

  20. Heat shock protein expression as guidance for the therapeutic window of retinal laser therapy

    NASA Astrophysics Data System (ADS)

    Wang, Jenny; Huie, Philip; Dalal, Roopa; Lee, Seungjun; Tan, Gavin; Lee, Daeyoung; Lavinksy, Daniel; Palanker, Daniel

    2016-03-01

    Unlike conventional photocoagulation, non-damaging retinal laser therapy (NRT) limits laser-induced heating to stay below the retinal damage threshold and therefore requires careful dosimetry. Without the adverse effects associated with photocoagulation, NRT can be applied to critical areas of the retina and repeatedly to manage chronic disorders. Although the clinical benefits of NRT have been demonstrated, the mechanism of therapeutic effect and width of the therapeutic window below damage threshold are not well understood. Here, we measure activation of heat shock response via laser-induced hyperthermia as one indication of cellular response. A 577 nm laser is used with the Endpoint Management (EpM) user interface, a titration algorithm, to set experimental pulse energies relative to a barely visible titration lesion. Live/dead staining and histology show that the retinal damage threshold in rabbits is at 40% of titration energy on EpM scale. Heat shock protein 70 (HSP70) expression in the retinal pigment epithelium (RPE) was detected by whole-mount immunohistochemistry after different levels of laser treatment. We show HSP70 expression in the RPE beginning at 25% of titration energy indicating that there is a window for NRT between 25% and 40% with activation of the heat shock protein expression in response to hyperthermia. HSP70 expression is also seen at the perimeter of damaging lesions, as expected based on a computational model of laser heating. Expression area for each pulse energy setting varied between laser spots due to pigmentation changes, indicating the relatively narrow window of non-damaging activation and highlighting the importance of proper titration.