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Sample records for quantitative bibliometric study

  1. An Expanding and Shifting Focus in Recent Environmental Health Literature: A Quantitative Bibliometric Study.

    PubMed

    Mao, Guozhu; Liu, Xi; Du, Huibin; Zuo, Jian; Li, Na

    2016-01-01

    This special report characterizes the patterns of environmental health literature from 1993 to 2012 by using bibliometric techniques based on databases of the Science Citation Index and the Social Science Citation Index. "Research article" was the most widely used document type, accounting for 71.7% of the total records (5,053), and 94.9% of these articles were published in English. The number of environmental health publications is growing along with an increasing level of communication. The U.S. was the largest contributing country with the highest h-index (85) and the most publications (1,854), followed by the UK and Canada. Environmental Health Perspectives and the Journal of Environmental Health were the top two most productive journals. The most cited article in each main research area is also listed. The authors' study not only identifies global characteristics in environmental health research, but also influences researchers' selection of future studies and publications.

  2. Bibliometric Studies of Scientific Productivity.

    DTIC Science & Technology

    1978-03-01

    In 1926, Alfred J. Lotka examined the scientific publishing productivity of chemists. His bibliometric study of the number of chemists listed in...square law’ of scientific productivity in which the frequency of authors publishing x papers varied inversely as the square of x. Bibliometric research is

  3. Japanese-Style Management: A Bibliometric Study.

    ERIC Educational Resources Information Center

    Noguchi, Sachie

    1988-01-01

    Reports results of a bibliometric study of the literature on Japanese-style management published in western languages from 1971-84 in order to: (1) determine Japanese contributions to the literature; (2) determine whether there are nuclear journals for the subject; and (3) investigate how the flow of information from Japan to overseas countries…

  4. [Bibliometric analysis of bacterial quantitative proteomics in English literatures].

    PubMed

    Zhang, Xin; She, Danyang; Liu, Youning; Wang, Rui; Di, Xiuzhen; Liang, Beibei; Wang, Yue

    2014-07-01

    To analyze the worldwide advances on bacterial quantitative proteomics over the past fifteen years with bibliometric approach. Literature retrieval was conducted throughout the databases of Pubmed, Embase and Science citation index (SCI), using "bacterium" and "quantitative proteomics" as the key words. The deadline is July 2013. We sorted and analyzed these articles with Endnote X6 from the aspects of published year, the first author, name of journal, published institution, cited frequency and publication type. 932 English articles were included in our research after deleting the duplicates. The first article on bacterial quantitative proteomics was reported in 1999. The maximal publications were 163 related articles in 2012. Up till July 2013, authors from more than 23 countries and regions have published articles in this field. China ranks the fourth. The main publication type is original articles. The most frequently cited article is entitled with "Absolute quantification of proteins by LCMSE: a virtue of parallel MS acquisition" by Silva JC, Gorenstein MV, Li GZ, et al in Mol Cell Proteomics 2006. The most productive author is Smith RD from Biological Sciences Division, Pac. Northwest National Laboratory. The top journal publishing bacterial quantitative proteomics is Proteomics. More and more researchers pay attention to quantitative proteomics which will be widely used in bacteriology.

  5. [Drifts and pernicious effects of the quantitative evaluation of research: the misuse of bibliometrics].

    PubMed

    Gingras, Yves

    2015-06-01

    The quantitative evaluation of scientific research relies increasingly on bibliometric indicators of publications and citations. We present the issues raised by the simplistic use of these methods and recall the dangers of using poorly built indicators and technically defective rankings that do not measure the dimensions they are supposed to measure, for example the of publications, laboratories or universities. We show that francophone journals are particularly susceptible to suffer from the bad uses of too simplistic bibliometric rankings of scientific journals.

  6. Combining Mapping and Citation Analysis for Evaluative Bibliometric Purposes: A Bibliometric Study.

    ERIC Educational Resources Information Center

    Noyons, E. C. M; Moed, H. F.; Luwel, M.

    1999-01-01

    Presents the results of a combined performance/mapping study used to evaluate a Belgian research institute in microelectronics. Results from one bibliometric approach were used to validate results of another. Findings indicated that the method provides a detailed and useful picture of the position of the institute from an international…

  7. [Knowledge production about nurse education: a bibliometric study].

    PubMed

    Lima, Margarete Maria de; Almeida, Alexsandro Barreto; Giovannetti, Monica de Oliveira; Backes, Vania Marli Schubert; Kloh, Daiana

    2012-01-01

    This study aims to identify the nursing theses and dissertation production catalogued in the Center for Study in Nursing Research - CEPEN, which treats nurse formation according to the National Curricular Directives on the SUS formation approach. This is a bibliometric and descriptive study performed on the theses and dissertations catalog of CEPEN, between 2003 and 2007. Twenty seven papers were selected, and quantitatively analyzed according to institution, year of publication, degree of research (dissertations or theses), type of research, and qualitatively analyzed according to themes, philosophical theory, and methodological reference. The results show 100% of the work performed in public institutions, with increased production in theses, there are few studies that deal with the profile of graduates, as well as training for SUS.

  8. Anatomy of the Generalized Inverse Gaussian-Poisson Distribution with Special Applications to Bibliometric Studies.

    ERIC Educational Resources Information Center

    Sichel, H. S.

    1992-01-01

    Discusses the use of the generalized inverse Gaussian-Poisson (GIGP) distribution in bibliometric studies. The main types of size-frequency distributions are described, bibliometric distributions in logarithms are examined; parameter estimation is discussed; and goodness-of-fit tests are considered. Examples of applications are included. (17…

  9. The Bibliometric Analysis Of Literature On Museum Studies

    NASA Astrophysics Data System (ADS)

    Kuo, C. W.; Yang, Y. H.

    2015-08-01

    Museum studies, is the study of museums, museum curation, and how and why museums developed into their institutional role in education and culture through scientific, social, political and other related forces. The purpose of this study is to shed light on the application trends of the international literature related to museum studies on the SCIE, SSCI, and AHCI databases between 1995 and 2014 using a bibliometric technique and citation analysis. The results of this study reveal that influences of the literature related to museum studies on other subject areas continue to expand. Considering the publication of major countries, subject areas, journal and institutions, the results also discussed that the future trend through analysing most cited articles. Moreover, 12 core journal lists are identified by Bradford's law.

  10. [Theses and dissertations of nurses about education in nursing and health: a bibliometric study].

    PubMed

    Backes, Vânia Marli Schubert; do Prado, Marta Lenise; Lino, Mônica Motta; Ferraz, Fabiane; Canever, Bruna Pedroso; Gomes, Diana Coelho; Martini, Jussara Gue

    2013-01-01

    The study aimed to describe the panorama of Education in Nursing and Health from abstracts of theses and dissertations published by nurses in Brazil between the years 2001 to 2009. This is a bibliometric, descriptive and quantitative study. Data were collected in the "Catalogue of Theses and Dissertations" from CEPEn/ABEn. After reading the abstracts and systematization of the material, analysis was performed using descriptive statistics. It was reviewed 4.101 studies, 523 of them on the theme of education. From these, 67% were dissertations and 33% of them were theses, predominantly produced in the southeast of Brazil. One conclude that the representation of the theme in the national context is significant and contributes to the advancement of knowledge in the field of Nursing, even though there are regional differences in the production process of this area of knowledge.

  11. [Bibliometrics study of the development trend of acupuncture-moxibustion clinical trials in foreign countries].

    PubMed

    He, Wei; Tong, Yuan-Yuan; Zhao, Ying-Kai; Rong, Pei-Jing; Wang, Hong-Cai

    2012-04-01

    On the basis of MEDLINE and EMBASE database, through bibliometrics, the quantitative research was conducted on the published literatures on the acupuncture-moxibustion clinical trial abroad. The situation of published articles in each continent, country and institution was analyzed statistically. It was found that the number of published articles was higher in Germany, America, England, Sweden, Austria, Japan, South Korea, etc. In Europe, the clinical trial of acupuncture and moxibustion was in the tendency of more country participants, wider distribution and larger amount of research. In North America, America was the main country for the study. In Asia, Japan and South Korea played the leading role. Of those countries, some institutions in Germany America, and South Korea were on the top of the list. In future, the above-mentioned countries and institutions should be monitored specifically so as to launch the active cooperation and strategic project.

  12. [Health education to ostomy patients: a bibliometrics study].

    PubMed

    Reveles, Audrey Garcia; Takahashi, Regina Toshie

    2007-06-01

    This study has as its objective to identify the scientific studies dealing with the orientation to patients submitted to ostomy published between 1970 to 2004 and to classify them according to quantity, chronology of publication, authors' function, source, kind of study, topic, origin and key words by using the bibliometrics methodology. A total of 27 publications were collected in the DEDALUS databank, in the LILACS and MEDLINE databases and from a professor of the University of São Paulo's Nursing School (EEUSP, which is a national reference in ostomy in Brazil). Of these, 19 were written by Brazilians and 8 by non-Brazilians; most were written by nurses and enterostomal therapists. Dissertations, theses, orientation manuals, books and articles were found. The origin of the material was academia, laboratories and hospitals. The 1990s concentrated the largest number of studies in this thematic area. All of them have the purpose of elevating patients' self-esteem in order to make them feel that, even with an ostomy, they can have a normal life. Thus the study concludes that the nurse, as an educator for the ostomy patient, should be acquainted with those publications to improve the assistance he/she provides.

  13. Growth of Headache Research: A 1983-2014 bibliometric study.

    PubMed

    Robert, Claude; Wilson, Concepción S; Lipton, Richard B; Arreto, Charles-Daniel

    2016-11-11

    This study charts the growth of the scientific journal literature on headache for 30+ years (1983-2014). Using the Web of Science, articles published in four two-year periods (1983-1984, 1993-1994, 2003-2004, 2013-2014) from journals indexed in the Science Citation Index Expanded database were retrieved and analyzed. From 1983-1984 to 2013-2014, the scientific literature on headache increased nearly fourfold (3.8) from 468 to 1776 articles; the number of participating countries more than doubled (26 to 67); and the two most prolific countries in each period were the USA and Italy. While several European countries (Italy, Germany, UK and Denmark) were among the top 10 in each period, the notable appearance of Turkey, China and Brazil among the top 10 in 2013-2014 indicates the growing geographic spread of publications on headache research. Meanwhile, the comet-like distribution of journals has not changed: two journals, Headache and Cephalalgia, persist throughout as the nucleus, with the tail increasing more than threefold from 141 journals in 1983-1984 to 462 in 2013-2014. Our study follows the recent growth and spread of the scientific literature on headache research and should stimulate further bibliometric investigation in this field. © International Headache Society 2016.

  14. Worldwide interest in the comet assay: a bibliometric study.

    PubMed

    Neri, Monica; Milazzo, Daniele; Ugolini, Donatella; Milic, Mirta; Campolongo, Alessandra; Pasqualetti, Patrizio; Bonassi, Stefano

    2015-01-01

    The comet assay is a rapid, sensitive and relatively simple method for measuring DNA damage. A bibliometric study was performed to evaluate temporal and geographical trends, research quality and main areas of interest in scientific production in this field. A PubMed search strategy was developed and 7674 citations were retrieved in the period 1990-2013. Notably, the MeSH (Medical Subject Headings) term 'comet assay', officially introduced in 2000, is used by indexers only in two thirds of papers retrieved. Articles on the comet assay were published in 78 countries, spread over the 5 continents. The EU contributed the greatest output, producing >2900 articles with IF (42.0%) and totalling almost 10000 IF points, and was followed by USA. In the new millennium, research with this assay reached a plateau or slow decline in the most industrialised areas (USA, Germany, UK, Italy), while its use has boomed in emerging countries, with increases of 5- to 7-fold in the last 10 years in China, India and Brazil, for instance. This transition resulted in a slow decrease of scientific production quality, as the countries that increased their relative weight typically had lower mIFs. The most common MeSH terms used in papers using the comet assay referred to wide areas of interest, such as DNA damage and repair, cell survival and apoptosis, cancer and oxidative stress, occupational and environmental health. Keywords related to humans, rodents and cell culture were also frequently used. The top journal for the comet assay articles was found to be Mutation Research, followed by Mutagenesis. Most papers using the comet assay as a biomarker were published in genetic and toxicology journals, with a stress on environmental and occupational disciplines.

  15. Professional Competencies and Jurisdictional Claims in Evaluative Bibliometrics: The Educational Mandate of Academic Librarians

    ERIC Educational Resources Information Center

    Petersohn, Sabrina

    2016-01-01

    Quantitative metrics in research assessment are proliferating all over the world. The demand has led to an increase in bibliometric practitioners and service providers. Their professional roles and competencies have not yet been subject to systematic study. This paper focuses on one important service provider in evaluative bibliometrics--academic…

  16. Professional Competencies and Jurisdictional Claims in Evaluative Bibliometrics: The Educational Mandate of Academic Librarians

    ERIC Educational Resources Information Center

    Petersohn, Sabrina

    2016-01-01

    Quantitative metrics in research assessment are proliferating all over the world. The demand has led to an increase in bibliometric practitioners and service providers. Their professional roles and competencies have not yet been subject to systematic study. This paper focuses on one important service provider in evaluative bibliometrics--academic…

  17. Disciplinary and Research Subjects in French Doctoral Dissertations in Press and Media Studies: A Bibliometric Treatment

    ERIC Educational Resources Information Center

    Herubel, Jean-Pierre V. M.

    2007-01-01

    For English-speaking researchers, French doctoral dissertations can represent a "terra incognita." For this reason, a retrospective bibliometric study of French dissertations in press and media studies offers a useful profile of available research to researchers concentrating in studies of the press and other media. The present study…

  18. Collaboration Patterns as a Function of Article Genre among Mixed Researchers: A Mixed Methods Bibliometric Study

    ERIC Educational Resources Information Center

    Jordan, John; Wachsmann, Melanie; Hoisington, Susan; Gonzalez, Vanessa; Valle, Rachel; Lambert, Jarod; Aleisa, Majed; Wilcox, Rachael; Benge, Cindy L.; Onwuegbuzie, Anthony J.

    2017-01-01

    Surprisingly, scant information exists regarding the collaboration patterns of mixed methods researchers. Thus, the purpose of this mixed methods bibliometric study was to examine (a) the distribution of the number of co-authors in articles published in the flagship mixed methods research journal (i.e., "Journal of Mixed Methods…

  19. Bibliometric analysis of Human Factors (1970-2000): a quantitative description of scientific impact.

    PubMed

    Dee, John D; Cassano-Pinché, Andrea; Vicente, Kim J

    2005-01-01

    Bibliometric analyses use the citation history of scientific articles as data to measure scientific impact. This paper describes a bibliometric analysis of the 1682 papers and 2413 authors published in Human Factors from 1970 to 2000. The results show that Human Factors has substantial relative scientific influence, as measured by impact, immediacy, and half-life, exceeding the influence of comparable journals. Like other scientific disciplines, human factors research is a highly stratified activity. Most authors have published only one paper, and many papers are cited infrequently, if ever. A small number of authors account for a disproportionately large number of the papers published and citations received. However, the degree of stratification is not as extreme as in many other disciplines, possibly reflecting the diversity of the human factors discipline. A consistent trend of more authors per paper parallels a similar trend in other fields and may reflect the increasingly interdisciplinary nature of human factors research and a trend toward addressing human-technology interaction in more complex systems. Ten of the most influential papers from each of the last 3 decades illustrate trends in human factors research. Actual or potential applications of this research include considerations for the publication and distribution policy of Human Factors.

  20. Quo Vadis Clozapine? A Bibliometric Study of 45 Years of Research in International Context.

    PubMed

    López-Muñoz, Francisco; Sanz-Fuentenebro, Javier; Rubio, Gabriel; García-García, Pilar; Álamo, Cecilio

    2015-09-23

    We have carried out a bibliometric study about the international scientific publications on clozapine. We have used the EMBASE and MEDLINE databases, and we applied bibliometric indicators of production, as Price's Law on the increase of scientific literature. We also calculated the participation index (PI) of the different countries. The bibliometric data have also been correlated with some social and health data from the 12 most productive countries in biomedicine and health sciences. In addition, 5607 original documents dealing with clozapine, published between 1970 and 2013, were downloaded. Our results state non-fulfilment of Price's Law, with scientific production on clozapine showing linear growth (r=0.8691, vs. r=0.8478 after exponential adjustment). Seven of the 12 journals with the highest numbers of publications on clozapine have an Impact Factor>2. Among the countries generating clozapine research, the most prominent is the USA (PI=24.32), followed by the UK (PI=6.27) and Germany (PI=5.40). The differences among countries on clozapine research are significantly related to economic variables linked to research. The scientific interest in clozapine remains remarkable, although after the application of bibliometric indicators of production, a saturation point is evident in the growth of scientific literature on this topic.

  1. Quo Vadis Clozapine? A Bibliometric Study of 45 Years of Research in International Context

    PubMed Central

    López-Muñoz, Francisco; Sanz-Fuentenebro, Javier; Rubio, Gabriel; García-García, Pilar; Álamo, Cecilio

    2015-01-01

    We have carried out a bibliometric study about the international scientific publications on clozapine. We have used the EMBASE and MEDLINE databases, and we applied bibliometric indicators of production, as Price’s Law on the increase of scientific literature. We also calculated the participation index (PI) of the different countries. The bibliometric data have also been correlated with some social and health data from the 12 most productive countries in biomedicine and health sciences. In addition, 5607 original documents dealing with clozapine, published between 1970 and 2013, were downloaded. Our results state non-fulfilment of Price’s Law, with scientific production on clozapine showing linear growth (r = 0.8691, vs. r = 0.8478 after exponential adjustment). Seven of the 12 journals with the highest numbers of publications on clozapine have an Impact Factor > 2. Among the countries generating clozapine research, the most prominent is the USA (PI = 24.32), followed by the UK (PI = 6.27) and Germany (PI = 5.40). The differences among countries on clozapine research are significantly related to economic variables linked to research. The scientific interest in clozapine remains remarkable, although after the application of bibliometric indicators of production, a saturation point is evident in the growth of scientific literature on this topic. PMID:26404263

  2. Bibliometrics for Social Validation

    PubMed Central

    2016-01-01

    This paper introduces a bibliometric, citation network-based method for assessing the social validation of novel research, and applies this method to the development of high-throughput toxicology research at the US Environmental Protection Agency. Social validation refers to the acceptance of novel research methods by a relevant scientific community; it is formally independent of the technical validation of methods, and is frequently studied in history, philosophy, and social studies of science using qualitative methods. The quantitative methods introduced here find that high-throughput toxicology methods are spread throughout a large and well-connected research community, which suggests high social validation. Further assessment of social validation involving mixed qualitative and quantitative methods are discussed in the conclusion. PMID:28005974

  3. Bibliometrics for Social Validation.

    PubMed

    Hicks, Daniel J

    2016-01-01

    This paper introduces a bibliometric, citation network-based method for assessing the social validation of novel research, and applies this method to the development of high-throughput toxicology research at the US Environmental Protection Agency. Social validation refers to the acceptance of novel research methods by a relevant scientific community; it is formally independent of the technical validation of methods, and is frequently studied in history, philosophy, and social studies of science using qualitative methods. The quantitative methods introduced here find that high-throughput toxicology methods are spread throughout a large and well-connected research community, which suggests high social validation. Further assessment of social validation involving mixed qualitative and quantitative methods are discussed in the conclusion.

  4. Academic Impact of Qualitative Studies in Healthcare: Bibliometric Analysis

    PubMed Central

    Mori, Hiroko; Nakayama, Takeo

    2013-01-01

    Context Although qualitative studies are becoming more appreciated in healthcare, the number of publications of quality studies remains low. Little is known about the frequency and characteristics of citation in qualitative studies. Objective To compare the academic impact of qualitative studies to that of two quantitative studies: systematic reviews and randomized controlled trials. Methods Publications in BMJ between 1997 and 2006 (BMJ’s median impact factor was 7.04 during this period) employing qualitative methods were matched to two quantitative studies appearing the same year using PubMed. Using Web of Science, citations within a 24-month publication period were determined. Additionally, three hypotheses were examined: qualitative studies are 1) infrequently cited in original articles or reviews; 2) rarely cited by authors in non-English-speaking countries; and 3) more frequently cited in non-medical disciplines (e.g., psychology or sociology). Results A total of 121 qualitative studies, 270 systematic reviews, and 515 randomised controlled trials were retrieved. Qualitative studies were cited a total of 1,089 times, with a median of 7.00 times (range, 0–34) for each study. Matched systematic reviews and randomized controlled trials were cited 2,411times and 1,600 times, respectively. With respect to citing documents, original articles and reviews exceeded 60% for each study design. Relative to quantitative studies, qualitative studies were cited more often by authors in English-speaking countries. With respect to subject area, medical disciplines were more frequently cited than non-medical disciplines for all three study designs (>80%). Conclusion The median number of citations for qualitative studies was almost the same as the median of BMJ’s impact factor during the survey period. For a suitable evaluation of qualitative studies in healthcare, it will be necessary to develop a reporting framework and include explicit discussions of clinical

  5. Telescope Bibliometrics 101

    NASA Astrophysics Data System (ADS)

    Grothkopf, Uta; Lagerstrom, Jill

    During recent years, bibliometric studies have become increasingly important in evaluating individual scientists, institutes, and entire observatories. In astronomy, often librarians are involved in maintaining publication databases and compiling statistics for their institutions. In this paper, we present a look behind the scenes to understand who is interested in bibliometric statistics, which methodologies astronomy librarians apply, and what kind of features next-generation bibliographies may include.

  6. Why Bibliometrics?

    NASA Astrophysics Data System (ADS)

    Lagerstrom, J.

    2012-08-01

    Why bibliometrics? This presentation will give a brief overview of the history of bibliometrics. More specific to astronomy, this presentation will discuss the results of a survey which will reveal how various facilities HST, Chandra, ground-based, etc. are using various aspects of paper- and citation-counting to provi de information about their research output.

  7. A Bibliometric Study to Manage a Journal Collection in an Astronomical Library: Some Results

    NASA Astrophysics Data System (ADS)

    Gomez, Monique

    The evaluation of the use of library collections is a fundamental tool for the development of a relevant and cost-effective collection. Bibliometrics offers several methods to measure the level of use of collections. In this paper, we present the first results of a bibliometric analysis of the references cited in the articles published by authors of the Instituto de Astrofísica de Canarias during the last decade. We have determined which kinds of publications and which journals are mainly used. We also have studied the ages of the cited journals and their cost-effectiveness. Additionally, to see if the advent of the WWW in the mid 1990s has influenced the reading or citing practices of the authors, we have compared two sets of data: articles published over the period 1991--3 that we define as the pre-WWW period and articles published over the period 1997--9 defined as the WWW period.

  8. A bibliometric study of the scientific publications on patient-reported outcomes in rheumatology.

    PubMed

    Redondo, Marta; Leon, Leticia; Povedano, Francisco Javier; Abasolo, Lydia; Perez-Nieto, Miguel Angel; López-Muñoz, Francisco

    2017-06-01

    We have conducted a bibliometric study of the scientific publications on patient-reported outcomes in the field of rheumatology. SCOPUS was the database used in this bibliometric study. We performed two searches. The main search involved selecting the documents published between 2000 and 2014 limited to top-tier journals addressing rheumatic and musculoskeletal diseases, using specific descriptors together with the operator and main descriptor "patient-reported outcomes" (PROs), and we performed a secondary search, with the following specific descriptors: "pain," "functional capacity," and "fatigue." We used bibliometric indicators for articles distribution (Price's law for the increase of scientific literature and Bradford's law for dispersion of articles). We also calculated the participation index of the different countries. A total of 983 original articles were published between 2000 and 2014. Our results confirmed the fulfilment of Price's law (correlation coefficient r = 0.9385 after linear adjustment). The average number of articles per Bradford Zone was 327.6. A total of 30 different journals were published. The type of growth for the descriptors "pain" (r(2) = 0.5417 compared to r(2) = 0.4839) and "fatigue" (r(2) = 06276 compared to r(2) = 0.5544) is exponential, whereas it is linear for the descriptor "functional capacity" (r(2) = 0.6769 compared to r(2) = 0.3779). This study revealed significant linear growth of patient-related outcomes in global terms, as well as upward trends for most of the citation-based bibliometric indices, especially significant from 2010 to 2014. Pain and fatigue have greater growth as PRO concepts. Copyright © 2017 Elsevier Inc. All rights reserved.

  9. Trends in Scientific Literature on Atypical Antipsychotics in South Korea: A Bibliometric Study

    PubMed Central

    Shen, Winston W.; Pae, Chi-Un; Moreno, Raquel; Rubio, Gabriel; Molina, Juan D.; Noriega, Concha; Pérez-Nieto, Miguel A.; Huelves, Lorena; Álamo, Cecilio

    2013-01-01

    Objective We have carried out a bibliometric study on the scientific publications in relation to atypical or second-generation antipsychotic drugs (SGAs) in South Korea. Methods With the EMBASE and MEDLINE databases, we selected those publications made in South Korea whose title included the descriptors atypic* (atypical*) antipsychotic*, second-generation antipsychotic*, clozapine, risperidone, olanzapine, ziprasidone, quetiapine, sertindole, aripiprazole, paliperidone, amisulpride, zotepine, asenapine, iloperidone, lurasidone, perospirone and blonanserin. We applied some bibliometric indicators of paper production and dispersion with Price's law and Bradford's law, respectively. We also calculated the participation index (PI) of the different countries, and correlated the bibliometric data with some social and health data from Korea (such as total per capita expenditure on health and gross domestic expenditure on research and development). Results We collected 326 original papers published between 1993 and 2011. Our results state fulfilment of fulfilled Price's law, with scientific production on SGAs showing exponential growth (correlation coefficient r=0.8978, as against an r=0.8149 after linear adjustment). The most widely studied drugs were risperidone (91 papers), aripiprazole (77), olanzapine (53), and clozapine (43). Division into Bradford zones yielded a nucleus occupied by the Progress in Neuro-Psychopharmacology and Biological Psychiatry (36 articles). A total of 86 different journals were published, with 4 of the first 10 used journals having an impact factor being greater than 4. Conclusion The publications on SGAs in South Korea have undergone exponential growth over the studied period, without evidence of reaching a saturation point. PMID:23482954

  10. A bibliometric analysis of cancer research in South Africa: study protocol

    PubMed Central

    Moodley, Jennifer; Singh, Vedantha; Kagina, Benjamin M; Abdullahi, Leila; Hussey, Gregory D

    2015-01-01

    Introduction Cancer is an important and growing public health burden in South Africa (SA). Over the past few decades, there has been considerable scientific activity in cancer in SA. However, there has been limited analysis of cancer scientific publications. In this paper, we present a protocol for bibliometric analysis of cancer research conducted in SA. Methods and analysis A comprehensive search of the journal databases PubMed, SCOPUS, Web of Science and EBSCO will be conducted to identify and retrieve data from primary peer-reviewed cancer research articles using a set of consensus search words. Articles that involve cancer research conducted in SA or using biological or clinical data from South African participants and published between 2004 and 2014 will be included in the study. Two independent researchers will screen the articles for eligibility. Bibliometric indicators and study characteristics will be extracted, entered into a database and analysed. The cancer disease site will be recorded and research will be classified using the Common Scientific Outline system. Data obtained will be analysed to determine SA's publication productivity index in cancer research. Annual trends in bibliometric indicators and the type of cancer research will be determined. The degree of collaboration in research conducted in SA will be analysed using co-authorship matrix software. A publication to disease type ratio will be used to assess scientific production relative to disease burden. Ethics and dissemination As this analysis will draw on publicly available data and does not directly involve human participants, ethical review is not required. We anticipate that the bibliometric analysis will identify the trends in cancer research productivity and the extent to which cancer research is aligned to the local burden of disease. Results will be published in peer-reviewed journals and presented in a user-friendly format to relevant policymakers and funders. PMID:25678542

  11. A bibliometric analysis of cancer research in South Africa: study protocol.

    PubMed

    Moodley, Jennifer; Singh, Vedantha; Kagina, Benjamin M; Abdullahi, Leila; Hussey, Gregory D

    2015-02-12

    Cancer is an important and growing public health burden in South Africa (SA). Over the past few decades, there has been considerable scientific activity in cancer in SA. However, there has been limited analysis of cancer scientific publications. In this paper, we present a protocol for bibliometric analysis of cancer research conducted in SA. A comprehensive search of the journal databases PubMed, SCOPUS, Web of Science and EBSCO will be conducted to identify and retrieve data from primary peer-reviewed cancer research articles using a set of consensus search words. Articles that involve cancer research conducted in SA or using biological or clinical data from South African participants and published between 2004 and 2014 will be included in the study. Two independent researchers will screen the articles for eligibility. Bibliometric indicators and study characteristics will be extracted, entered into a database and analysed. The cancer disease site will be recorded and research will be classified using the Common Scientific Outline system. Data obtained will be analysed to determine SA's publication productivity index in cancer research. Annual trends in bibliometric indicators and the type of cancer research will be determined. The degree of collaboration in research conducted in SA will be analysed using co-authorship matrix software. A publication to disease type ratio will be used to assess scientific production relative to disease burden. As this analysis will draw on publicly available data and does not directly involve human participants, ethical review is not required. We anticipate that the bibliometric analysis will identify the trends in cancer research productivity and the extent to which cancer research is aligned to the local burden of disease. Results will be published in peer-reviewed journals and presented in a user-friendly format to relevant policymakers and funders. Published by the BMJ Publishing Group Limited. For permission to use (where not

  12. Bibliometrics, Librarians, and Bibliograms

    ERIC Educational Resources Information Center

    White, Howard D.

    2016-01-01

    This paper sets forth an integrated way of introducing bibliometrics to relatively non-quantitative audiences, such as librarians and iSchool students. The integrative device is the bibliogram, a linguistic object consisting of a seed term and the terms that co-occur with it, ranked by their co-occurrence counts with the seed--a standard…

  13. Bibliometrics, Librarians, and Bibliograms

    ERIC Educational Resources Information Center

    White, Howard D.

    2016-01-01

    This paper sets forth an integrated way of introducing bibliometrics to relatively non-quantitative audiences, such as librarians and iSchool students. The integrative device is the bibliogram, a linguistic object consisting of a seed term and the terms that co-occur with it, ranked by their co-occurrence counts with the seed--a standard…

  14. Dermatologic research in the Nordic countries 1989-2008--a bibliometric study.

    PubMed

    Gjersvik, Petter; Nylenna, Magne; Jemec, Gregor B E; Haraldstad, Anne-Marie

    2010-11-01

    Bibliometric methods, based on the count of articles published in scientific journals, are increasingly used to evaluate scientific productivity. Bibliometric studies may identify factors that promote or inhibit research performance. We set out to analyze dermatologic research activity in Sweden, Denmark, Finland, and Norway using bibliometric methods. We performed repetitive searches on Medline, using the PubMed interface, for the period 1989-2008. Dermatologic articles were defined as all articles in dermatologic journals plus articles in nondermatologic journals in which the address of first author included an institution of dermatology. Articles were allocated to the country of first author's address. The number of dermatologic articles from Sweden, Denmark, Finland, and Norway was 1896 (214 per million inhabitants), 1502 (281), 1017 (196), and 249 (55), respectively. Dermatologic articles represented 1.4%, 2.3%, 1.6%, and 0.6% of each country's total number of Medline articles in English over the same period. Similar patterns were found in relation to gross domestic product, number of dermatologists, and number of medical schools. After 2000, the yearly number of dermatologic articles from Denmark increased and that from Finland decreased, whereas the numbers from Sweden and Norway remained relatively stable. Despite similarities in social and economic conditions in Sweden, Denmark, Finland, and Norway, there are great differences in dermatologic research activity in the four countries, with Denmark performing best and Norway poorest. Historical and cultural factors may partly explain these differences. © 2010 The International Society of Dermatology.

  15. Palliative care and nursing in dissertations and theses in Portugal: a bibliometric study.

    PubMed

    Ferreira, Maria Amélia Leite; Pereira, Alexandra Manuela Nogueira de Andrade; Martins, José Carlos Amado; Barbieri-Figueiredo, Maria do Céu

    2016-04-01

    To identify the academic scientific production on palliative care in master dissertations and PhD theses carried out by nurses in Portugal. A descriptive retrospective study of bibliometric type with search for the abstracts available in repositories of higher education institutions in the period 2000-2014. Of the 1814 papers identified, 249 met the inclusion criteria (ten doctoral theses and 239 master dissertations). The most representative methodological approach was quantitative (31.35%) and the most studied area was family/informal caregiver (20.69%). The most studied target population were the students/health professionals (38.51%). The academic scientific production in this area has been growing in spite of the need for continued investment in order to fill the identified gaps. Identificar a produção científica académica sobre cuidados paliativos nos estudos de mestrados e doutoramentos efetuados por enfermeiros em Portugal. Estudo descritivo e retrospetivo, do tipo bibliométrico, recorrendo aos resumos disponíveis nos repositórios das instituições de ensino superior no período 2000-2014. Dos 1814 trabalhos identificados, 249 corresponderam aos critérios de inclusão (10 teses de doutoramento e 239 dissertações de mestrado). A abordagem metodológica mais representativa é a quantitativa (31,35%), a área mais estudada foi a família/cuidador informal (20,69%) e a população-alvo mais estudada foram os estudantes/profissionais de saúde (38,51%). A produção científica académica nessa área tem vindo a crescer. Embora exista necessidade de investimento contínuo de forma a colmatar as lacunas identificadas.

  16. A bibliometric study of scientific research conducted on second-generation antipsychotic drugs in Singapore.

    PubMed

    López-Muñoz, Francisco; Sim, Kang; Shen, Winston Wu; Huelves, Lorena; Moreno, Raquel; Molina, Juan de Dios; Rubio, Gabriel; Noriega, Concha; Pérez-Nieto, Miguel Ángel; Alamo, Cecilio

    2014-01-01

    A bibliometric study was carried out to ascertain the volume and impact of scientific literature published on second-generation antipsychotic drugs (SGAs) in Singapore from 1997 to 2011. A search of the EMBASE and MEDLINE databases was performed to identify articles originating from Singapore that included the descriptors 'atypic* antipsychotic*', 'second-generation antipsychotic*', 'clozapine', 'risperidone', 'olanzapine', 'ziprasidone', 'quetiapine', 'sertindole', 'aripiprazole', 'paliperidone', 'amisulpride', 'zotepine', 'asenapine', 'iloperidone', 'lurasidone', 'perospirone' and 'blonanserin' in the article titles. Certain bibliometric indicators of production and dispersion (e.g. Price's Law on the increase of scientific literature, and Bradford's Law) were applied, and the participation index of various countries was calculated. The bibliometric data was also correlated with some social and health data from Singapore, such as the total per capita expenditure on health and gross domestic expenditure on research and development. From 1997 to 2011, a total of 51 articles on SGAs in Singapore were published. Our results suggested non-fulfilment of Price's Law (r = 0.0648 after exponential adjustment vs. r = 0.2140 after linear adjustment). The most widely studied drugs were clozapine (21 articles), risperidone (16 articles) and olanzapine (8 articles). Division into Bradford zones yielded a nucleus occupied by the Journal of Clinical Psychopharmacology (6 articles) and the Singapore Medical Journal(4 articles). The analysed material was published in a total of 30 journals, with the majority from six journals. Four of these six journals have an impact factor greater than 2. Publications on SGAs in Singapore are still too few to confirm an exponential growth of scientific literature.

  17. A bibliometric study of scientific research conducted on second-generation antipsychotic drugs in Singapore

    PubMed Central

    López-Muñoz, Francisco; Sim, Kang; Shen, Winston Wu; Huelves, Lorena; Moreno, Raquel; Molina, Juan de Dios; Rubio, Gabriel; Noriega, Concha; Ángel Miguel, Pérez-Nieto; Álamo, Cecilio

    2014-01-01

    INTRODUCTION A bibliometric study was carried out to ascertain the volume and impact of scientific literature published on second-generation antipsychotic drugs (SGAs) in Singapore from 1997 to 2011. METHODS A search of the EMBASE and MEDLINE databases was performed to identify articles originating from Singapore that included the descriptors ‘atypic* antipsychotic*’, ‘second-generation antipsychotic*’, ‘clozapine’, ‘risperidone’, ‘olanzapine’, ‘ziprasidone’, ‘quetiapine’, ‘sertindole’, ‘aripiprazole’, ‘paliperidone’, ‘amisulpride’, ‘zotepine’, ‘asenapine’, ‘iloperidone’, ‘lurasidone’, ‘perospirone’ and ‘blonanserin’ in the article titles. Certain bibliometric indicators of production and dispersion (e.g. Price's Law on the increase of scientific literature, and Bradford's Law) were applied, and the participation index of various countries was calculated. The bibliometric data was also correlated with some social and health data from Singapore, such as the total per capita expenditure on health and gross domestic expenditure on research and development. RESULTS From 1997 to 2011, a total of 51 articles on SGAs in Singapore were published. Our results suggested non-fulfilment of Price's Law (r = 0.0648 after exponential adjustment vs. r = 0.2140 after linear adjustment). The most widely studied drugs were clozapine (21 articles), risperidone (16 articles) and olanzapine (8 articles). Division into Bradford zones yielded a nucleus occupied by the Journal of Clinical Psychopharmacology (6 articles) and the Singapore Medical Journal (4 articles). The analysed material was published in a total of 30 journals, with the majority from six journals. Four of these six journals have an impact factor greater than 2. CONCLUSION Publications on SGAs in Singapore are still too few to confirm an exponential growth of scientific literature. PMID:24452974

  18. Combining new technologies for effective collection development: a bibliometric study using CD-ROM and a database management program.

    PubMed Central

    Burnham, J F; Shearer, B S; Wall, J C

    1992-01-01

    Librarians have used bibliometrics for many years to assess collections and to provide data for making selection and deselection decisions. With the advent of new technology--specifically, CD-ROM databases and reprint file database management programs--new cost-effective procedures can be developed. This paper describes a recent multidisciplinary study conducted by two library faculty members and one allied health faculty member to test a bibliometric method that used the MEDLINE and CINAHL databases on CD-ROM and the Papyrus database management program to produce a new collection development methodology. PMID:1600424

  19. Assistive technology for people with dementia: an overview and bibliometric study.

    PubMed

    Asghar, Ikram; Cang, Shuang; Yu, Hongnian

    2017-03-01

    This study presents an overview of recent research activities in assistive technology (AT) for people with dementia. Bibliometric studies are used to explore breadth and depth of different research areas, yet this method has not yet been fully utilised in AT research for people with dementia. The bibliometric method was used for collecting studies related to AT. Based on inclusion/exclusion criteria, the AT studies with a focus on people with dementia are considered. The study is based on factors such as number of publications, citations per paper, collaborative research output, P-Index, major research and application areas and national dementia strategies. Data were collected from 2000 to 2014 in AT research. The top 10 countries are selected based on their research outputs. USA emerged as the leading contributor with 503 publications and an annual growth rate of 16%, followed by UK with 399 publications and growth rate of 22%. Germany with 101 publications is on the 6th place, but it has a higher citation rate 16.43% as compared to USA (13.34%). Although all 10 countries show good collaborative research output, Italy, Spain and the Netherlands emerge as top collaborative research contributors with high percentages (84%, 84% and 79%). All the top 10 countries, except Canada, Germany and Spain, have national dementia strategies in place. The overall analysis shows that USA and UK are working extensively in AT research for people with dementia. Both these countries also have well established national dementia strategies. © 2017 Health Libraries Group.

  20. Developing Comparative Bibliometric Indicators for Evaluating the Research Performance of Four Academic Nutrition Departments, 1992-1996: An Exploratory Study.

    ERIC Educational Resources Information Center

    Ackermann, Eric George

    This study develops a set of empirically and theoretically sound citation-based bibliometric indicators of scientific research performance and applies them in an exploratory comparative study of the University of Tennessee-Knoxville's (UTK's) Nutrition Department with three of its peer programs at the University of Florida, the University of…

  1. Bibliometric Analysis of Parasitological Research in Iran and Turkey: A Comparative Study

    PubMed Central

    Rashidi, A; Rahimi, B; Delirrad, M

    2013-01-01

    Background This study was designed to assess and compare the quantity and quality of Iranian and Turkish researchers working in the field of Parasitology from bibliometric point of view. Methods To assess the contributions and achievements of the Iranian and Turkish parasitologists, bibliometric analysis was carried out based on the citation data retrieved from Web of Science. Results The absolute productivity of Turkish and Iranian parasitologists’ papers has almost tripled for Turkey, from 12 papers in 2002 to 36 papers in 2011, and decuple for Iran, from 10 papers to 123 from 2002 to 2010. The average number of citation per article is about 5.8 and 4 for Turkish and Iranian parasitologists’ papers, respectively. The “Veterinary Parasitology” journal was the most cited journal in both countries. The majority (more than 90%) of cited items was foreign journal articles and one half of all references in journals articles dated 11 and 12 years while one half of cited books was dated within 14 to16 years for Turkish and Iranian papers, respectively. Conclusion Based on observed data and applied model, it is anticipated that the total number of Iranian and Turkish parasitologists’ publications in Web of Science will exceed of 2512 and 240 articles per annum for Iranian and Turkish in 2020, respectively. PMID:23914246

  2. Map of Scientific Publication in the Field of Educational Sciences and Teacher Education in Turkey: A Bibliometric Study

    ERIC Educational Resources Information Center

    Çiftçi, Serife Koza; Danisman, Sahin; Yalçin, Mikail; Tosuntas, Sule Betül; Ay, Yusuf; Sölpük, Nihan; Karadag, Engin

    2016-01-01

    This study aims to create a map for the scientific publications in the field of educational sciences and teacher education in Turkey. A bibliometric analysis was carried out with 7681 articles published in 32 different peer reviewed journals between 2005 and 2014. The findings show that one third of all articles were published in core journals…

  3. Early Approaches to Bibliometrics.

    ERIC Educational Resources Information Center

    Broadus, Robert N.

    1987-01-01

    Traces the history of the field of bibliometrics from ancient times to 1969, when the term was proposed as a substitute for "statistical bibliography," and discusses the theories of Lotka, Zipf, and Bradford; library use studies; citation analyses and bibliographic coupling. (Author/EM)

  4. [Research on quality of health care from the Mexican Social Security Institute: a bibliometric study].

    PubMed

    Navarrete-Navarro, Susana; Gómez-Delgado, Alejandro; Riebeling-Navarro, Carlos; López-García, Gloria Araceli; Nava-Zavala, Arnulfo

    2013-12-01

    OBJECTIVE. To identify studies on quality of health care in the IMSS. MATERIALS AND METHODS. A bibliometric, descriptive cross-sectional and retrospective study was conducted, from 1992 to 2011. RESULTS. We identified 881 research studies related to the issue of quality (CI95% 10.6-12.0) of 7 762 studies presented at the annual research meetings. 10 521 articles were published in this period of time and only 946 (CI95% 8.4-9.5) were linked to the issue of quality. CONCLUSIONS. The results of this study allowed us to identify the interest about research on quality. Further research is needed to establish what has been the impact on the improvement of quality in health care.

  5. Bibliometric Analysis of Medication Errors and Adverse Drug Events Studies.

    PubMed

    Huang, Hung-Chi; Wang, Cheng-Hua; Chen, Pi-Ching; Lee, Yen-Der

    2015-07-31

    Medication errors and adverse drug events are a key concern of the health-care industry. The objectives of this study were to map the intellectual structure of the studies of medication errors and adverse drug events and to investigate the developing path of this literature and interrelationships among the main topics. The Web of Science database was searched for documentation of medication errors and adverse drug events from 1961 to 2013. The most cited articles and references were profiled and analyzed using HistCite software to draw a historiograph and Ucinet software to draw a sociogram. The database search revealed 3343 medication errors and 3342 adverse drug event documents. The most cited articles on medication errors focused on 3 key themes from 1961 to 2013, namely, medication errors in adult inpatients, computerized physician order entry in medication error studies, and medication errors in pediatric inpatients. The developing path for the most cited articles about adverse drug events from 1987 to 2013 was as follows: detection, analysis, effect, and prevention from adult inpatient to pediatric inpatient settings and from hospitalized care to ambulatory care. In addition, social network analysis based on the most cited references revealed a close relationship between medication errors and adverse drug events. The mapping results provide a valuable tool for researchers to access the literature in this field and can be used to help identify the direction of medication errors and adverse drug events research.

  6. Bibliometric study of Medical Reference Services Quarterly, 1982-2009.

    PubMed

    Kenefick, Colleen; Werner, Susan E

    2011-01-01

    Medical Reference Services Quarterly began publication in 1982, covering topics of current interest and practical value to public services librarians in medical and related specialties. Since then, it has expanded in scope to include more aspects of health sciences librarianship. This article is a systematic study of all 428 peer-reviewed articles published from 1982 through 2009, with a comprehensive description of content and a citation analysis. Content is extensively analyzed for article subject, and cited references are examined for subject, type of cited material, and average age. In addition, author, institutional, and regional productivity is determined and ranked.

  7. [Trends and evolutions of French breast cancer research: a bibliometric study].

    PubMed

    Thonon, Frédérique; Saghatchian, Mahasti; Nerfie, Alexia; Delaloge, Suzette

    2015-05-01

    This article presents a bibliometric study carried out in order to describe the trends and evolutions of French breast cancer research from 2003 to 2013. The results show an increase in the number of publications, especially international publications coordinated by non-French institutions. The most visible topics, in terms of number of publications by keywords, are related to biology, clinical trials and genetics. Most publications are written by authors affiliated to comprehensive cancer centres, followed by universities, research centres, university hospitals and governmental agencies. The importance of publications by topic varies throughout the years: there has been an increase of the number of publications related to targeted therapies or genomics. The importance of institutions or country affiliation of authors varies with the topics. This study, especially the analysis by keywords, enables the coordinators of research programs to identify the predominant actors and themes.

  8. Dupuytren's Contracture: A Bibliometric Study of the Most Cited Papers.

    PubMed

    Joyce, Cormac Weekes; Joyce, Kenneth Mary; Rahmani, George; Carroll, Sean Michael; Kelly, Jack Laurence; Regan, Padraic James

    2015-10-01

    The literature on Dupuytren's contracture is vast yet little information is known as to which papers have been the most influential. The purpose of this study was to identify the 50 most cited papers on Dupuytren's contracture and perform a citation analysis. Utilizing the Web of Science, 23 surgical, medical, plastic and hand surgery journals were searched for papers on Dupuytren's contracture. Resulting articles were ranked in order of times cited and each paper was analyzed for article-type, year of publication, country of origin, institution and level of evidence. The 50 most cited articles represent many important landmarks in Dupuytren's treatment and contain several seminal works by experts in the field. Whilst the top 50 list highlights the important papers on the condition, they certainly do not provide information about the quality of the evidence of the research, as most papers presented level 4 or 5 evidence.

  9. Bibliometric study of grey literature in core veterinary medical journals

    PubMed Central

    Pelzer, Nancy L.; Wiese, William H.

    2003-01-01

    Objectives: Grey literature has been perceived by many as belonging to the primary sources of information and has become an accepted method of nonconventional communication in the sciences and medicine. Since little is known about the use and nature of grey literature in veterinary medicine, a systematic study was done to analyze and characterize the bibliographic citations appearing in twelve core veterinary journals. Methods: Citations from 2,159 articles published in twelve core veterinary journals in 2000 were analyzed to determine the portion of citations from grey literature. Those citations were further analyzed and categorized according to the type of publication. Results: Citation analysis yielded 55,823 citations, of which 3,564 (6.38%) were considered to be grey literature. Four veterinary specialties, internal medicine, pathology, theriogenology, and microbiology, accounted for 70% of the total number of articles. Three small-animal clinical practice journals cited about 2.5–3% grey literature, less than half that of journals with basic research orientations, where results ranged from almost 6% to approximately 10% grey literature. Nearly 90% of the grey literature appeared as conferences, government publications, and corporate organization literature. Conclusions: The results corroborate other reported research that the incidence of grey literature is lower in medicine and biology than in some other fields, such as aeronautics and agriculture. As in other fields, use of the Internet and the Web has greatly expanded the communication process among veterinary professionals. The appearance of closed community email forums and specialized discussion groups within the veterinary profession is an example of what could become a new kind of grey literature. PMID:14566374

  10. Bibliometrics study on authorship trends in periodontal literature from 1995 to 2010.

    PubMed

    Geminiani, Alessandro; Ercoli, Carlo; Feng, Changyong; Caton, Jack G

    2014-05-01

    Biomedical research has grown considerably in the last few decades, and the authorship characteristics of the dental literature as a whole and of its specialty fields has changed significantly. Unfortunately, the bibliometrics of the periodontal literature have not been thoroughly investigated. The aim of this study is to investigate the bibliometrics of periodontal literature, assessing the geographic origin, study design, and topics investigated in periodontal research published from 1995 to 2010. Articles published in periodontal journals during 1995 to 2010 were retrieved through hand search. Inclusion/exclusion criteria were applied. The following variables were extrapolated from each article: number of authors, study design, topic investigated, financial support, and geographic origin. The general linear model assessed the influence of independent variables on number of authors per article, and χ(2) test assessed the statistical difference of the variables over years 1995 to 2010. A total of 2,260 articles were reviewed; 2,076 met the inclusion criteria. The number of authors per article increased (P <0.001) from 4.0 (1995) to 5.1 (2010). The proportion of articles published from North America and Europe decreased (P <0.001) from 84.3% (1995) to 58.6% (2010), whereas for Asia and South America the article proportion increased (P <0.001) from 13.8% (1995) to 40% (2010). Research targeting prevention and treatment of periodontal disease is decreasing (P <0.001) in favor of implant-related research. Governmental research funding is increasing (P <0.001). Periodontal research significantly changed during the last 15 years.

  11. A Bibliometric and Trend Analysis on the Water-Related Risk Assessment Studies for Cryptosporidium Pathogen

    PubMed Central

    MESDAGHINIA, Alireza; YOUNESIAN, Masuod; NASSERI, Simin; NABIZADEH NODEHI, Ramin; HADI, Mahdi

    2015-01-01

    Background: The bibliometric methods have been used in many disciplines of sciences to study the scientific production and research trends. In this study, they were used to investigate research trends related to the risk assessment of Cryptosporidium pathogen in water field. Methods: Data were obtained on the Scopus database from 1993 to 2013. Research tendency was investigated by analyzing the distribution of languages, countries, journals, author keywords, authorship pattern and co-authorship relations. Results: The English language was dominant language of all publications (96.36%). Number of articles in this field increased from 2 in 1993 to 29 papers in 2007 and then received to 19 at the end of 2013. United States produced 35.41% of all pertinent articles followed by United Kingdom with 10.76% and Australia with 9.92%. Water Research Journal published the most papers in this field, taking 11.62% of all, followed by Journal of Water and Health (10.92%) and Water Science and Technology (10.21%). The most productive authors were Ashbolt NJ form Canada that accounts about 1.51% of the total publications followed by Rose JB and Haas CN from United States. Authorship pattern analysis results show that literature does follow Lotka’s law (P=0.627). Conclusion: A downward trend in the number of publications is likely to occur in future. The results of this bibliometric analysis may help relevant researchers realize the scope of the microbial risk assessment research of Cryptosporidium, and establish the further research direction. PMID:26622289

  12. A bibliometric study of scientific literature on the dietary therapies for epilepsy in Scopus.

    PubMed

    Morandi, Gabriella; Guido, Davide; Tagliabue, Anna

    2015-07-01

    The aim of this study was to provide a descriptive overview of the impact and production of literature on dietary therapies for epilepsy and perform a citation analysis of the related research articles. We searched for 'ketogenic OR low-glycemic OR medium chain OR modified Atkins in TITLE AND epilep*' in Title/Abstract/Keyword in Scopus database. A total of 661 references were retrieved, 80% had been published after 2000s, 87% were published in English, and 39% of the publications were published in nine journals. The majority (76.3%) of research articles describe the clinical application of the dietary therapies regarding the classical ketogenic diet (80%), followed by the modified Atkins diet (11.5%), medium chain triglyceride diet (6.4%), and low glycemic index treatment (2.0%); the remaining are basic science studies on the mechanisms of action. The citation analysis revealed that the latter have the highest percentage variation in citation per publication across the years. Concerning the article cohorts, the greatest number of citations per publication was in 1998. The overview of the literature on the dietary therapy of epilepsy evidences a growing interest in the field with a striking prevalence of clinical over basic science studies. The most cited clinical studies have validated the efficacy of the dietary therapies; the few studies on the mechanisms of action received a great number of citations. Bibliometric analysis measuring the trends and the impact of the scientific literature would help researchers to a best knowledge of this specific topic.

  13. A bibliometric study of international scientific productivity in giardiasis covering the period 1971-2010.

    PubMed

    Escobedo, Angel A; Arencibia, Ricardo; Vega, Rosa L; Rodríguez-Morales, Alfonso J; Almirall, Pedro; Alfonso, Maydel

    2015-01-15

    Despite years of relative neglect, interest in Giardia infection seems to be recently growing, perhaps in part due to its inclusion into the World Health Organization's Neglected Diseases Initiative since 2004. The purpose of this study was to provide an overview of Giardia and giardiasis research over time, as represented by the quantity of published papers. Data for this study were collected from the electronic PubMed/Medline database of National Library of Medicine's (NLM), due to it is easily accessibility and wide use. It was accessed online between April and December 2011. Data for the period 1971-2010 were obtained and information was downloaded using the EndNote program developed by Thomson Reuters. During the study period, a total of 6,964 references (articles, reviews, editorials, letter to the editor, etc.) covering different aspects of Giardia and giardiasis were located in the PubMed database after applying the search strategy reported above. Most papers were original articles and published in English. In this first effort to explore the development and research productivity on giardiasis over time (no previously published bibliometric studies on giardiasis exist), two interesting characteristics of the Giardia and giardiasis literature were discovered: the concentration of papers over journals disseminating the research results, and that research in this field is growing and will likely continue to grow in the coming years.

  14. Community pharmacy based research activity in India: A bibliometric study of the past ten years.

    PubMed

    Basak, Subal Chandra; Sathyanarayana, Dondeti

    2010-02-01

    The objective of this study was to analyze and record the published evidence regarding community pharmacy practice in India during the past decade (1998-2008). A bibliometric review analysis of the original papers was undertaken to assess the different aspects of community pharmacy practice in India. The MEDLINE, Index Copernicus, IndMed, DOAJ databases and the journals such as Indian Journal of Pharmaceutical Sciences and Indian Journal of Hospital Pharmacy were used as data sources. Type of papers, type of journals, category of papers, production indicators and impact factor of the journals were analyzed. Thirty papers were included in the study. The papers were published in 13 different journals, 33.3% of them being in the Indian Journal of Hospital Pharmacy. The average number of authors per paper was 2.73 (SD=1.41). Impact factor was available for only three journals. There are limited studies being published in India which cover the community pharmacy related activities in India. The key indicators which emerge from the literature review present some fundamental challenges to the development of the role of the community pharmacist in India.

  15. Community pharmacy based research activity in India: A bibliometric study of the past ten years

    PubMed Central

    Basak, Subal Chandra; Sathyanarayana, Dondeti

    2010-01-01

    Objectives: The objective of this study was to analyze and record the published evidence regarding community pharmacy practice in India during the past decade (1998-2008). Methods: A bibliometric review analysis of the original papers was undertaken to assess the different aspects of community pharmacy practice in India. The MEDLINE, Index Copernicus, IndMed, DOAJ databases and the journals such as Indian Journal of Pharmaceutical Sciences and Indian Journal of Hospital Pharmacy were used as data sources. Type of papers, type of journals, category of papers, production indicators and impact factor of the journals were analyzed. Results: Thirty papers were included in the study. The papers were published in 13 different journals, 33.3% of them being in the Indian Journal of Hospital Pharmacy. The average number of authors per paper was 2.73 (SD=1.41). Impact factor was available for only three journals. Conclusions: There are limited studies being published in India which cover the community pharmacy related activities in India. The key indicators which emerge from the literature review present some fundamental challenges to the development of the role of the community pharmacist in India. PMID:23093877

  16. [Bibliometric study of the production and use of the Farmacia Hospitalaria journal (2004-2012)].

    PubMed

    Sanz-Valero, J; Tomás-Casterá, V; Tomás-Gorriz, V

    2014-01-01

    To analyze the scientific activity and the production of information of the Farmacia Hospitalaria journal as the Spanish scientific publication of reference in the pharmaceutical area. Transversal descriptive study of the results obtained from the bibliometric analysis of the articles published in the journal. Data was obtained from direct queries and Internet access to the scientific literature contained in the electronic version of the journal during the 2004-2012 period. During the period studied 756 articles were published. The number of original articles was 258 (34.12%) with a productivity index of 2.40. The number of institutions identified with published articles was 246. The predominant language was Spanish with 733 (96.96%) articles. We counted 1828 keywords, of which 527 (28.83%) coincided with MeSH. The median calculation of the obsolescence of quoted references was 10, and the Price Index was 8.81%. The percentage of selfquotes was 5.18%. We confirmed a low proportion of original articles and an adequate percentage of satisfactory quotable articles. The low percentage of keywords that coincide with Medical Subject Headings is noteworthy. The bibliographical references found in the articles come mainly from the English-speaking area and from journals indexed in the Journal Citation Report. The obsolescence analysis of these references produced high results.

  17. [Bibliometrics study on indications of acupuncture therapy based on foreign acupuncture clinical trials].

    PubMed

    He, Wei; Tong, Yuan-Yuan; Zhao, Ying-Kai; Rong, Pei-Jing; Wang, Hong-Cai

    2012-10-01

    In the present paper, the authors make a bibliometrics study on clinical indications of acupuncture therapy based on the published foreign articles about acupuncture clinical trials collected from PubMed database and Excerpta Medica database (EMbase). In 1996, 64 acupuncture indications were declared by WHO in Milan conference. But in recent 15 years, clinical trials have been conducted extensively in the foreign countries. Till now, 77 new indications for acupuncture therapy have been found in the foreign journals. The authors recommended that 29 indications (knee osteoarthritis, critique age problems, muscular fasciae ache, anxiety, etc.) should be added to the first class, 4 indications (irritable bowel syndrome, malposition, backache, simple obesity) should be upgraded from the second class to the first class, and the other 3 indications (childbirth pain, male and female barren) should be upgraded from the third class to the first class due to their application frequency in clinical trials. Increase of clinical indications reflects extensive application of acupuncture therapy and may help providing a better service for people's health.

  18. World orofacial pain research production: a bibliometric study (2004-2005).

    PubMed

    Robert, Claude; Caillieux, Nicolas; Wilson, Concepción S; Gaudy, Jean-François; Arreto, Charles-Daniel

    2008-01-01

    To provide a snapshot of the scientific literature on orofacial pain. The authors identified 975 papers related to orofacial pain in the Current Contents Life Sciences and Clinical Medicine collections of the Thomson Scientific database that were published during 2004 and 2005 and analyzed them using bibliometric indicators. Among the 54 countries involved, the United States ranks first by number of papers (293), followed by Japan (107), and the United Kingdom (90). The high volume of research activity in some Northern European countries is highlighted, along with that of the European Union (384 papers). The scientific literature on orofacial pain was published in 247 journals; 13 of the top 15 most prolific journals for articles on orofacial pain were found in the Dentistry, Oral Surgery and Medicine subdiscipline of Current Contents/Clinical Medicine, and the Journal of Orofacial Pain was the highest ranked for such articles. This study complements subject reviews of orofacial pain research and provides a more complete picture of the research activity in this field.

  19. Disclosures, conflict of interest, and funding issues in urogynecology articles: a bibliometric study.

    PubMed

    Koch, Marianne; Riss, Paul; Kölbl, Heinz; Umek, Wolfgang; Hanzal, Engelbert

    2015-10-01

    The ethical behavior of authors, editors, and journals is increasingly placed in the spotlight, by both the public and the research community. Disclosures and conflict of interest (COI) statements of publishing authors represent one important aspect. We aimed to unravel the current management of disclosures, COI, and funding statements in the subspecialty urogynecology. A bibliometric study was carried out. We included six journals that published urogynecology articles between January and December 2013. All original articles, reviews, and opinion articles were assessed for the presence of disclosure/COI and funding statements. Information given on the official disclosure form was compared with information given in the final article (International Urogynecology Journal). All journals investigated require disclosure and funding statements in their instructions to authors. Of the 434 articles included, almost all contained a disclosure statement (98-100 %). Funding statements were present in 41-100 % of articles, indicating a difference in journal type (50 % on average among urogynecology journals; 75 % on average among general gynecology journals). The main source of funding was "grants" (58 %), followed by "none" (16 %), "industry" (16 %), and lastly "hospital/university" (10 %). Disclosure statements in the article were identical to the official disclosure form in 80 % (IUJ). Disclosure/COI statements were included in almost all urogynecology articles investigated. Their content, however, is sometimes incomplete and should possibly be monitored more closely by journals and authors. Despite universal requirements of journals, the reporting of funding seems inconsistent. This issue in addition to the completeness of disclosures should be given more attention.

  20. Research Trends in the Study of ICT Based Learning Communities: A Bibliometric Analysis

    ERIC Educational Resources Information Center

    Hernández, Jonathan Bermúdez; Chalela, Salim; Arias, Jackeline Valencia; Arias, Alejandro Valencia

    2017-01-01

    The current opportunities to develop and acquire knowledge in the network, Information and Communications Technology (ICT) play a major role in the learning process. This research offers a bibliometric analysis in order to examine the state of the research activity carried out in relation to the learning communities based on ICT. The indicators…

  1. Research Trends in the Study of ICT Based Learning Communities: A Bibliometric Analysis

    ERIC Educational Resources Information Center

    Hernández, Jonathan Bermúdez; Chalela, Salim; Arias, Jackeline Valencia; Arias, Alejandro Valencia

    2017-01-01

    The current opportunities to develop and acquire knowledge in the network, Information and Communications Technology (ICT) play a major role in the learning process. This research offers a bibliometric analysis in order to examine the state of the research activity carried out in relation to the learning communities based on ICT. The indicators…

  2. Yoga as a Therapeutic Intervention: A Bibliometric Analysis of Published Research Studies from 1967 to 2013

    PubMed Central

    Slutsky, Jeremiah; Singh, Nilkamal; Khalsa, Sat Bir S.

    2015-01-01

    Abstract Objective: A comprehensive bibliometric analysis was conducted on publications for yoga therapy research in clinical populations. Methods: Major electronic databases were searched for articles in all languages published between 1967 and 2013. Databases included PubMed, PsychInfo, MEDLINE, IndMed, Indian Citation Index, Index Medicus for South-East Asia Region, Web of Knowledge, Embase, EBSCO, and Google Scholar. Nonindexed journals were searched manually. Key search words included yoga, yoga therapy, pranayama, asana. All studies met the definition of a clinical trial. All styles of yoga were included. The authors extracted the data. Results: A total of 486 articles met the inclusion criteria and were published in 217 different peer-reviewed journals from 29 different countries on 28,080 study participants. The primary result observed is the three-fold increase in number of publications seen in the last 10 years, inclusive of all study designs. Overall, 45% of the studies published were randomized controlled trials, 18% were controlled studies, and 37% were uncontrolled studies. Most publications originated from India (n=258), followed by the United States (n=122) and Canada (n=13). The top three disorders addressed by yoga interventions were mental health, cardiovascular disease, and respiratory disease. Conclusion: A surge in publications on yoga to mitigate disease-related symptoms in clinical populations has occurred despite challenges facing the field of yoga research, which include standardization and limitations in funding, time, and resources. The population at large has observed a parallel surge in the use of yoga outside of clinical practice. The use of yoga as a complementary therapy in clinical practice may lead to health benefits beyond traditional treatment alone; however, to effect changes in health care policy, more high-quality, evidence-based research is needed. PMID:26196166

  3. Yoga as a Therapeutic Intervention: A Bibliometric Analysis of Published Research Studies from 1967 to 2013.

    PubMed

    Jeter, Pamela E; Slutsky, Jeremiah; Singh, Nilkamal; Khalsa, Sat Bir S

    2015-10-01

    A comprehensive bibliometric analysis was conducted on publications for yoga therapy research in clinical populations. Major electronic databases were searched for articles in all languages published between 1967 and 2013. Databases included PubMed, PsychInfo, MEDLINE, IndMed, Indian Citation Index, Index Medicus for South-East Asia Region, Web of Knowledge, Embase, EBSCO, and Google Scholar. Nonindexed journals were searched manually. Key search words included yoga, yoga therapy, pranayama, asana. All studies met the definition of a clinical trial. All styles of yoga were included. The authors extracted the data. A total of 486 articles met the inclusion criteria and were published in 217 different peer-reviewed journals from 29 different countries on 28,080 study participants. The primary result observed is the three-fold increase in number of publications seen in the last 10 years, inclusive of all study designs. Overall, 45% of the studies published were randomized controlled trials, 18% were controlled studies, and 37% were uncontrolled studies. Most publications originated from India (n=258), followed by the United States (n=122) and Canada (n=13). The top three disorders addressed by yoga interventions were mental health, cardiovascular disease, and respiratory disease. A surge in publications on yoga to mitigate disease-related symptoms in clinical populations has occurred despite challenges facing the field of yoga research, which include standardization and limitations in funding, time, and resources. The population at large has observed a parallel surge in the use of yoga outside of clinical practice. The use of yoga as a complementary therapy in clinical practice may lead to health benefits beyond traditional treatment alone; however, to effect changes in health care policy, more high-quality, evidence-based research is needed.

  4. Trends in performance indicators of neuroimaging anatomy research publications: a bibliometric study of major neuroradiology journal output over four decades based on web of science database.

    PubMed

    Wing, Louise; Massoud, Tarik F

    2015-01-01

    Quantitative, qualitative, and innovative application of bibliometric research performance indicators to anatomy and radiology research and education can enhance cross-fertilization between the two disciplines. We aim to use these indicators to identify long-term trends in dissemination of publications in neuroimaging anatomy (including both productivity and citation rates), which has subjectively waned in prestige during recent years. We examined publications over the last 40 years in two neuroradiological journals, AJNR and Neuroradiology, and selected and categorized all neuroimaging anatomy research articles according to theme and type. We studied trends in their citation activity over time, and mathematically analyzed these trends for 1977, 1987, and 1997 publications. We created a novel metric, "citation half-life at 10 years postpublication" (CHL-10), and used this to examine trends in the skew of citation numbers for anatomy articles each year. We identified 367 anatomy articles amongst a total of 18,110 in these journals: 74.2% were original articles, with study of normal anatomy being the commonest theme (46.7%). We recorded a mean of 18.03 citations for each anatomy article, 35% higher than for general neuroradiology articles. Graphs summarizing the rise (upslope) in citation rates after publication revealed similar trends spanning two decades. CHL-10 trends demonstrated that more recently published anatomy articles were likely to take longer to reach peak citation rate. Bibliometric analysis suggests that anatomical research in neuroradiology is not languishing. This novel analytical approach can be applied to other aspects of neuroimaging research, and within other subspecialties in radiology and anatomy, and also to foster anatomical education. © 2014 Wiley Periodicals, Inc.

  5. Community pharmacy-based research in Spain (1995-2005): A bibliometric study

    PubMed Central

    Andrés Iglesias, José Carlos; Andrés Rodríguez, N. Floro; Fornos Pérez, José Antonio

    Only one study evaluated the scientific activity in community pharmacies in Spain, and it was restricted to articles published in just two journals. Objective To assess the scientific activity in community pharmacies in Spain through a bibliometric analysis of the original papers published during the years 1995-2005. Methods IPA, MEDLINE, CSIC database and the journals Seguimiento Farmacoterapéutico y Pharmaceutical Care España were used as data sources. Production indicators, consumption indicators and the impact factor (IF) as a repercussion index were analyzed. Results 122 articles were included in the review. The articles were published in 12 journals, 78.7% of them in Pharmaceutical Care España and Seguimiento Farmacoterapéutico. The mean number of authors per article was 4.2 (SD=2.1). The transitivity index was 71.3%. The total number of references cited in the articles was 2110. The mean number of references per article was 17.3 SD=9.3. The value of the insularity index was 57.6%. Self citation was 6.8% and the Price index was 66.5%. No impact factor was available for 6 journals. Conclusions Publication of articles on community pharmacy-based research in Spain has undergone an important increase in the last 5 years. The existence of authors who publish very few studies, the high insularity index and the lack of randomized, controlled trials may be considered as negative indicators in community pharmacy-based research in Spain. PMID:25214914

  6. Regional inequality in radiology research output in the UK: a 5-year bibliometric study.

    PubMed

    Yoong, P; Johnson, C A; Rehman, J M; Toms, A P

    2012-11-01

    The objective of this study was to describe the patterns of peer-reviewed general radiology publication rates with reference to deaneries in the UK. This was a retrospective bibliometric analysis of publications in the six highest cited general radiology journals. Publications were identified using a manual search in PubMed between 2005 and 2009. Publications originating from UK radiology departments were identified and subcategorised into primary institution of origin, deanery and publication type. The total number of radiology trainees in each deanery was obtained from the General Medical Council. 913 publications were included in the study. Original papers constituted 48.7% (n=445), review articles 30.3% (n=277) and case reports 17.4% (n=159). The median number of publications in each deanery was 27 [interquartile range (IQR) 11-60], and the median number of publications per trainee was 0.49 (IQR 0.31-0.88). The largest proportion of publications came from the London deanery (n=354, 38.8%), followed by Eastern 86 (9.4%), Oxford and Yorkshire 70 (7.7% each). Relative to the number of trainees within each deanery, Oxford had the highest number of publications per trainee (1.78), followed by East Midlands (1.5), London (1.25) and Eastern (0.99). There was a significantly higher publication rate for those deaneries with academic radiologists (p<0.0001). There is a marked difference in the volume of published work in the general radiology literature among UK deaneries, even accounting for differences in the number of trainees. This probably means that opportunities for training in research are similarly non-uniform.

  7. Bibliometrics, dermatology and contact dermatitis.

    PubMed

    Smith, Derek R

    2008-09-01

    Although the fields of bibliometrics and citation analysis have existed for many years, relatively few studies have specifically focused on the dermatological literature. This article reviews citation-based research in the dermatology journals, with a particular interest in manuscripts that have included Contact Dermatitis as part of their analysis. Overall, it can be seen that the rise of bibliometrics during the mid-20th century and its subsequent application to dermatology has provided an interesting insight into the progression of research within our discipline. Further investigation of citation trends and top-cited papers in skin research periodicals would certainly help complement the current body of knowledge.

  8. China's growing contribution to sepsis research from 1984 to 2014: A bibliometric study.

    PubMed

    Zhang, Kai; Zhao, Jialian; Chu, Lihua; Jin, Yue; Cheng, Baoli; Xie, Guohao; Wang, Yan; Fang, Xiangming

    2017-06-01

    The aim of this study was to analyze the global trends of sepsis research and investigate China's contribution by comparing the quantity and quality of sepsis-related publications. Sepsis-related publications were main retrieved from the Web of Science online database by using the keywords "sepsis" or "septic shock." Bibliometric indicators, including the number of publications, total citation frequency, citation frequency per paper, h-index, research type, orientation, organization, author, journal, and funding support were analyzed. From 1984 to 2014, a total of 70,564 papers regarding sepsis research were published worldwide. 3.60% of which were contributed by authors from Chinese institutions. Although this contribution was less than the Unites States, Germany, England, France or Japan, a notable trend of increase in a number of scientific publications (r  =  0.57, P < .001), with an average annual growth rate of 20.78%, was observed. The quality of the publications was relatively low in China. Basic research was a clear dominant representation, accounting for 50.46% of China's sepsis research. The research centers in China were mainly located in Beijing (5 centers), Shanghai (4 centers), and Hong Kong (3 centers). The National Natural Science Foundation of China supported the most Chinese sepsis researches. Global sepsis research developed swiftly during the 1984 to 2014 period. The USA was in the forefront of sepsis research. Although the data indicated that China had a large increasing rate of publications, there was a considerable gap in the quality of articles between China and other developed countries.

  9. A Bibliometric Analysis of Climate Engineering Research

    NASA Astrophysics Data System (ADS)

    Belter, C. W.; Seidel, D. J.

    2013-12-01

    The past five years have seen a dramatic increase in the number of media and scientific publications on the topic of climate engineering, or geoengineering, and some scientists are increasingly calling for more research on climate engineering as a possible supplement to climate change mitigation and adaptation strategies. In this context, understanding the current state of climate engineering research can help inform policy discussions and guide future research directions. Bibliometric analysis - the quantitative analysis of publications - is particularly applicable to fields with large bodies of literature that are difficult to summarize by traditional review methods. The multidisciplinary nature of the published literature on climate engineering makes it an ideal candidate for bibliometric analysis. Publications on climate engineering are found to be relatively recent (more than half of all articles during 1988-2011 were published since 2008), include a higher than average percentage of non-research articles (30% compared with 8-15% in related scientific disciplines), and be predominately produced by countries located in the Northern Hemisphere and speaking English. The majority of this literature focuses on land-based methods of carbon sequestration, ocean iron fertilization, and solar radiation management and is produced with little collaboration among research groups. This study provides a summary of existing publications on climate engineering, a perspective on the scientific underpinnings of the global dialogue on climate engineering, and a baseline for quantitatively monitoring the development of climate engineering research in the future.

  10. [Bibliometric study of the journal Actas Dermo-Sifiliográficas (1984-2003). I. Production analysis].

    PubMed

    Miralles, Julia; Ramos, José M; Ballester, Rosa; Belinchón, Isabel; Sevila, Amparo; Moragón, Manuel

    2005-10-01

    Analyze the scientific articles published in Actas Dermo-Sifiliográficas (AD) between 1984 and 2003. The main bibliometric parameters analyzed were: number of articles, their length and type, primary subject areas, authorship of the documents, main contributing centers, departmental areas and geographic distribution of the articles. All of the scientific articles published in the regular issues of the journal Actas Dermo-Sifiliográficas between 1984 and 2003 (two decades), corresponding to volumes 75 to 94, were reviewed manually. A total of 2,604 articles were published in the journal AD during the period studied, with a yearly average of 130 articles. Clinical cases or notes were the main type of document (66.2 %), followed by original articles (23.5 %) and review articles (4.7 %). The length of the documents varied from 1 to 33 pages, with an average of 4.55 pages. The subjects that were most discussed in the documents from this period were dermatopathology (15.9 %) and therapeutics (15.4 %). A total of 11,667 authorships were found, with 2,907 different authors. The average number of authors per article for the period was 4.48. 56.7 % of the authors were occasional contributors (having signed a single document), while 3.5 % were top contributors, having signed 20 or more works over this period. Seven Autonomous Communities accounted for 85.5 % of the articles. The Community of Madrid was by far the largest contributor (917 documents, 35.2 %), followed by Andalusia (422, 16.2 %), Catalonia (240, 9.2 %) and Castile-León (221, 8.5 %). The 2,604 documents in the study were from 293 different centers, which accounted for 2,977 co-authorships. Most of these co-authorships were from large hospitals or hospital complexes. The most noteworthy of these were the Madrid hospitals 12 de Octubre (281 co-authorships) and Clínico San Carlos (153), and Hospital Universitario San Cecilio in Granada (149). Dermatology was the specialty of most of the authors (90.8 % of those

  11. At the Leading Front of Neuroscience: A Bibliometric Study of the 100 Most-Cited Articles

    PubMed Central

    Yeung, Andy W. K.; Goto, Tazuko K.; Leung, W. Keung

    2017-01-01

    Background: It might be difficult for clinicians and scientists to identify comprehensively the major research topics given the large number of publications. A bibliometric report that identifies the most-cited articles within the body of the relevant literature may provide insight and guidance for readers toward scientific topics that are considered important for researchers and all relevant workers of academia. To our knowledge, there is a lack of an overall evaluation of the most-cited articles and hence of a comprehensive review of major research topics in neuroscience. The present study was therefore proposed to analyze and characterize the 100 most-cited articles in neuroscience. Methods: Based on data provided from Web of Science, the 100 most-cited articles relevant to neuroscience were identified and characterized. Information was extracted for each included article to assess for the publication year, journal published, impact factor, adjusted impact factor, citation count (total, normalized, and adjusted), reference list, authorship and article type. Results: The total citation count for the 100 most-cited articles ranged from 7,326 to 2,138 (mean 3087.0) and the normalized citation count ranged from 0.163 to 0.007 (mean 0.054). The majority of the 100 articles were research articles (67%) and published from 1996 to 2000 (30%). The author and journal with the largest share of these 100 articles were Stephen M. Smith (n = 6) and Science (n = 13) respectively. Among the 100 most-cited articles, 37 were interlinked via citations of one another, and they could be classified into five major topics, four of which were scientific topics, namely neurological disorders, prefrontal cortex/emotion/reward, brain network, and brain mapping. The remaining topic was methodology. Interestingly 41 out of 63 of the rest, non-interlinked articles could also be categorized under the above five topics. Adjusted journal impact factor among these 100 articles did not appear to

  12. At the Leading Front of Neuroscience: A Bibliometric Study of the 100 Most-Cited Articles.

    PubMed

    Yeung, Andy W K; Goto, Tazuko K; Leung, W Keung

    2017-01-01

    Background: It might be difficult for clinicians and scientists to identify comprehensively the major research topics given the large number of publications. A bibliometric report that identifies the most-cited articles within the body of the relevant literature may provide insight and guidance for readers toward scientific topics that are considered important for researchers and all relevant workers of academia. To our knowledge, there is a lack of an overall evaluation of the most-cited articles and hence of a comprehensive review of major research topics in neuroscience. The present study was therefore proposed to analyze and characterize the 100 most-cited articles in neuroscience. Methods: Based on data provided from Web of Science, the 100 most-cited articles relevant to neuroscience were identified and characterized. Information was extracted for each included article to assess for the publication year, journal published, impact factor, adjusted impact factor, citation count (total, normalized, and adjusted), reference list, authorship and article type. Results: The total citation count for the 100 most-cited articles ranged from 7,326 to 2,138 (mean 3087.0) and the normalized citation count ranged from 0.163 to 0.007 (mean 0.054). The majority of the 100 articles were research articles (67%) and published from 1996 to 2000 (30%). The author and journal with the largest share of these 100 articles were Stephen M. Smith (n = 6) and Science (n = 13) respectively. Among the 100 most-cited articles, 37 were interlinked via citations of one another, and they could be classified into five major topics, four of which were scientific topics, namely neurological disorders, prefrontal cortex/emotion/reward, brain network, and brain mapping. The remaining topic was methodology. Interestingly 41 out of 63 of the rest, non-interlinked articles could also be categorized under the above five topics. Adjusted journal impact factor among these 100 articles did not appear to

  13. Dictionary of Bibliometrics.

    ERIC Educational Resources Information Center

    Diodato, Virgil

    This dictionary explains 225 terms used in bibliometrics, and it provides nontechnical definitions of bibliometric concepts and suggests sources where more information can be found about the defined term. Special features include sample references, cross references, variants (synonyms), and an index of names. The introduction relates the terms of…

  14. Bibliometric analysis of scientific literature on intestinal parasites in Argentina during the period 1985-2014.

    PubMed

    Basualdo, Juan A; Grenóvero, María S; Bertucci, Evangelina; Molina, Nora B

    2016-01-01

    The study of scientific production is a good indicator of the progress in research and knowledge generation. Bibliometrics is a scientific discipline that uses a set of indicators to quantitatively express the bibliographic characteristics of scientific publications. The scientific literature on the epidemiology of intestinal parasites in Argentina is scattered in numerous sources, hindering access and visibility to the scientific community. Our purpose was to perform a quantitative, bibliometric study of the scientific literature on intestinal parasites in humans in Argentina published in the period 1985-2014. This bibliometric analysis showed an increase in the number of articles on intestinal parasites in humans in Argentina published over the past 30 years. Those articles showed a collaboration index similar to that of the literature, with a high index of institutionality for national institutions and a very low one for international collaboration. The original articles were published in scientific journals in the American Continent, Europe and Asia. The use of bibliometric indicators can provide a solid tool for the diagnosis and survey of the research on epidemiology of intestinal parasites and contributes to the dissemination and visibility of information on the scientific production developed in Argentina. Copyright © 2016 Asociación Argentina de Microbiología. Publicado por Elsevier España, S.L.U. All rights reserved.

  15. [Definition and use of bibliometrics in research].

    PubMed

    Sillet, Arnauld

    2013-12-01

    Bibliometrics is a tool used to achieve quantitative research assessment exercises of academic output, teams or even individuals in the field of scientific research. It is also important to know the basics of this method such as the impact factor, the h-index and how journals are evaluated.

  16. A bibliometric study of international scientific productivity in attention-deficit hyperactivity disorder covering the period 1980-2005.

    PubMed

    López-Muñoz, Francisco; Alamo, Cecilio; Quintero-Gutiérrez, Francisco Javier; García-García, Pilar

    2008-09-01

    We have carried out a bibliometric analysis of scientific publications related to attention-deficit hyperactivity disorder (ADHD) and its pharmacological treatment over the period 1980-2005. We selected (in EMBASE and MEDLINE databases) documents that contained in their title the descriptors attention deficit hyperactivity disorder, attention deficit disorder, ADHD and ADD. As bibliometric indicators of production and dispersion we applied Price's Law and Bradford's Law, respectively. We also calculated the national participation index (PI) and correlated it with overall PI in biomedical and health sciences, with PI in the discipline of Psychiatry and with the social-health indicators (per capita Gross Domestic Product, number of physicians and total per capita expenditure on health). We obtained 5,269 original documents (2,325 corresponded to pharmacological therapy). Our results indicate fulfilment of Price's Law, since scientific production on ADHD undergoes exponential growth (correlation coefficient r = 0.9859, vs. r = 0.9011 after linear adjustment). The most widely studied drugs are methylphenidate (1,251 documents). Division into Bradford zones yields a nucleus occupied exclusively by the Journal of the American Academy of Child and Adolescent Psychiatry (500 articles). A total of 866 different journals were employed. Twelve of the first 20 used journals have an Impact Factor > 2. The principal producer country is the United States (PI = 44.2). Only four countries, of the 20 major producers in health sciences, surpass their own PI in the field of Psychiatry (Brazil, China, Spain and the United States). The correlation between PI and total number of physicians for each country situates Canada, Australia, the United States and Israel in the top positions. Productivity on ADHD has undergone exponential growth in the period 1980-2005, without evidence a saturation point.

  17. [A bibliometrics study of literature on medical image processing for the past ten years].

    PubMed

    Chen, Wei; Wang, Yanbin; Ouyang, Zhaolian; Guo, Wenjiao; Chi, Hui

    2014-02-01

    We searched and retrieved literature on the topic of medical image processing published on SCI journals in the past 10 years. We then imported the retrieved literature into TDA for data cleanup before data analysis and pro cessing by EXCLE and UCINET to generate tables and figures that could indicate disciplinary correlation and research hotspots from the perspective of bibliometrics. The results indicated that people in Europe and USA were leading researchers on medical image processing with close international cooperation. Many disciplines contributed to the fast development of medical image processing with intense interdisciplinary researches. The papers that we found show recent research hotspots of the algorithm, system, model, image and segmentation in the field of medical image processing. Cluster analysis on key words of high frequency demonstrated complicated clustering relationship.

  18. A bibliometric study on chemical information and computer sciences focusing on literature of JCICS.

    PubMed

    Onodera, N

    2001-01-01

    A bibliometric approach was used to survey the state-of-the-art of research in the field of chemical information and computer sciences (CICS). By examining the CA database for the articles abstracted under the subsection "Chemical information, documentation, and data processing", Journal of Chemical Information and Computer Sciences (JCICS) was identified to have been the top journal in this subsection for the last 30 years. Based on this result, CA subsections and controlled index terms given to JCICS articles were analyzed to see trends in subjects and topics in the CICS field during the last two decades. These analyses revealed that the subjects of research in CICS have diversified from traditional information science and computer applications to chemistry to "molecular information sciences". The SCISEARCH database was used to grasp interdependency between JCICS and other key journals and also the international nature of JCICS in its publications and citedness.

  19. Bibliometrical Study of the Scientific Production and Citation of Dr. Guillermo Haro Barraza

    NASA Astrophysics Data System (ADS)

    Mata-Acosta, V.; Jiménez-Fragozo, M. E.; Figueroa-Servin, R. D.

    2010-10-01

    The main objective of this work is to characterize the bibliometric behavior of the scientific work of Dr. Guillermo Haro (March 21, 1913 - April 26, 1988). Professor Haro's scientific writings spanned from 1944 to 1988. In this paper, we consider citations made up until February 9, 2009. The methodology used is based on the creation of three databases. The first database is composed of a total of 93 articles with their publication data. The second database contains 710 references cited in those articles, and the third database comprises 830 citations retrieved from the NASA Astrophysics Data System, in addition to the archive that contains the complete text of the articles for their thematic analysis. For the interpretation of these data, several indicators and mathematical models were used which give us both the characteristics of the scientific communication of this author over the course of 44 years as well as the characteristics of the citations received.

  20. Yoga as a therapeutic intervention: a bibliometric analysis of published research studies.

    PubMed

    Khalsa, Sat Bir S

    2004-07-01

    Although yoga is historically a spiritual discipline, it has also been used clinically as a therapeutic intervention. A bibliometric analysis on the biomedical journal literature involving research on the clinical application of yoga has revealed an increase in publication frequency over the past 3 decades with a substantial and growing use of randomized controlled trials. Types of medical conditions have included psychopathological (e.g. depression, anxiety), cardiovascular (e.g. hypertension, heart disease), respiratory (e.g. asthma), diabetes and a variety of others. A majority of this research has been conducted by Indian investigators and published in Indian journals, particularly yoga specialty journals, although recent trends indicate increasing contributions from investigators in the U.S. and England. Yoga therapy is a relatively novel and emerging clinical discipline within the broad category of mind-body medicine, whose growth is consistent with the burgeoning popularity of yoga in the West and the increasing worldwide use of alternative medicine.

  1. [Bibliometric analysis of IBERPOC and EPI-SCAN studies. Contribution of the smoking variable on the iberpoc study].

    PubMed

    de Granda-Orive, J I; Alonso-Arroyo, A; López-Padilla, D; Segrelles-Calvo, G; Jiménez-Ruiz, C A; Solano-Reina, S

    2017-02-09

    The aim of this study was to perform a bibliometric analysis of EPI-SCAN and IBERPOC studies using the Science Citation Index and Scopus databases, and to determine the overall impact with the impact of smoking on IBERPOC as a secondary objective. A general searching was conducted in Science Citation Index-Expanded through the Web of Science (WoS) (Thomson Reuters) platform and Scopus on 23 March 2015. The search strategy included the terms "iberpoc" OR "episcan" was performed on 15 October 2015. A total of 24 publications were obtained; 13 from IBERPOC study (9 on "COPD" and 4 for "tobacco"), with 11 from the EPI-SCAN (All COPD) study. A total of 841 WoS citations were obtained (445 IBERPOC [99 of tobacco]), and 1,442 from Scopus (963 IBERPOC [144 tobacco]). The theme "tobacco" contributed with 22.24% and 14.95% of total citations in WoS and Scopus, respectively to the IBERPOC study. It was found that Scopus citations were newer, and a similar impact from both WoS studies was detected, although the IBERPOC impact was greater in Scopus. Collaborative networks of institutions and authors of both studies were identified. There is an important productivity and impact of both studies. Scopus citations are newer than those in WoS. The "tobacco" variable added IBERPOC impact and visibility. There was high density, accessibility, and cohesion in collaborative networks of both studies. Copyright © 2017 Sociedad Española de Médicos de Atención Primaria (SEMERGEN). Publicado por Elsevier España, S.L.U. All rights reserved.

  2. Universality in bibliometrics

    NASA Astrophysics Data System (ADS)

    da Silva, Roberto; Kalil, Fahad; de Oliveira, José Palazzo Moreira; Martinez, Alexandre Souto

    2012-03-01

    Many discussions have enlarged the literature in Bibliometrics since the Hirsch proposal, the so called h-index. Ranking papers according to their citations, this index quantifies a researcher only by its greatest possible number of papers that are cited at least h times. A closed formula for h-index distribution that can be applied for distinct databases is not yet known. In fact, to obtain such distribution, the knowledge of citation distribution of the authors and its specificities are required. Instead of dealing with researchers randomly chosen, here we address different groups based on distinct databases. The first group is composed of physicists and biologists, with data extracted from Institute of Scientific Information (ISI). The second group is composed of computer scientists, in which data were extracted from Google-Scholar system. In this paper, we obtain a general formula for the h-index probability density function (pdf) for groups of authors by using generalized exponentials in the context of escort probability. Our analysis includes the use of several statistical methods to estimate the necessary parameters. Also an exhaustive comparison among the possible candidate distributions are used to describe the way the citations are distributed among authors. The h-index pdf should be used to classify groups of researchers from a quantitative point of view, which is meaningfully interesting to eliminate obscure qualitative methods.

  3. Bibliometric Indicators versus Expert Opinion in Assessing Research Performance.

    ERIC Educational Resources Information Center

    Koenig, Michael E. D.

    1983-01-01

    This study comparing four major data aspects--expert judgment as to research performance, bibliometric variables, research output, and organizational size--in 19 pharmaceutical companies reveals a consistent tendency for bibliometric indicators to perform better than expert judgments in predicting research performance. Drug output regression…

  4. The evolution of dental journals from 2003 to 2012: a bibliometric analysis.

    PubMed

    Jayaratne, Yasas Shri Nalaka; Zwahlen, Roger Arthur

    2015-01-01

    Bibliometrics are a set of methods, which can be used to analyze academic literature quantitatively and its changes over time. The objectives of this study were 1) to evaluate trends related to academic performance of dental journals from 2003 to 2012 using bibliometric indices, and 2) monitor the changes of the five dental journals with the highest and lowest impact factor (IF) published in 2003. Data for the subject category "Dentistry, Oral Surgery & Medicine" was retrieved from the Journal Citation Reports (JCR) published from 2003 to 2012. Linear regressions analysis was used to determine statistical trends over the years with each bibliometric indicator as the dependent variable and the JCR year as the predictor variable. Statistically significant rise in the total number of dental journals, the number of all articles with the steepest rise observed for research articles, the number of citations and the aggregate IF was observed from 2003 to 2012. The analysis of the five top and five bottom-tire dental journals revealed a rise in IF however, with a wide variation in relation to the magnitude of this rise. Although the IF of the top five journals remained relatively constant, the percentile ranks of the four lowest ranking journals in 2003 increased significantly with the sharpest rise being noted for the British Journal of Oral & Maxillofacial Surgery. This study revealed significant growth of dental literature in absolute terms, as well as upward trends for most of the citation-based bibliometric indices from 2003 to 2012.

  5. The Evolution of Dental Journals from 2003 to 2012: A Bibliometric Analysis

    PubMed Central

    Jayaratne, Yasas Shri Nalaka; Zwahlen, Roger Arthur

    2015-01-01

    Bibliometrics are a set of methods, which can be used to analyze academic literature quantitatively and its changes over time. The objectives of this study were 1) to evaluate trends related to academic performance of dental journals from 2003 to 2012 using bibliometric indices, and 2) monitor the changes of the five dental journals with the highest and lowest impact factor (IF) published in 2003. Data for the subject category "Dentistry, Oral Surgery & Medicine" was retrieved from the Journal Citation Reports (JCR) published from 2003 to 2012. Linear regressions analysis was used to determine statistical trends over the years with each bibliometric indicator as the dependent variable and the JCR year as the predictor variable. Statistically significant rise in the total number of dental journals, the number of all articles with the steepest rise observed for research articles, the number of citations and the aggregate IF was observed from 2003 to 2012. The analysis of the five top and five bottom-tire dental journals revealed a rise in IF however, with a wide variation in relation to the magnitude of this rise. Although the IF of the top five journals remained relatively constant, the percentile ranks of the four lowest ranking journals in 2003 increased significantly with the sharpest rise being noted for the British Journal of Oral & Maxillofacial Surgery. This study revealed significant growth of dental literature in absolute terms, as well as upward trends for most of the citation-based bibliometric indices from 2003 to 2012. PMID:25781486

  6. Tracing thought through time and space: a selective review of bibliometrics in social work.

    PubMed

    Holden, Gary; Rosenberg, Gary; Barker, Kathleen

    2005-01-01

    Bibliometrics is a field of research that examines bodies of knowledge within and across disciplines. Citation analysis, a component of bibliometrics, focuses on the quantitative assessment of citation patterns within a body of literature. Citation analysis has been used in social work to examine the quantity and the impact of the work of individuals and academic institutions. This paper presents a selective review of these uses of bibliometrics within social work.

  7. [Approximation to the impact of biomedical journals in neurological sciences: study of bibliometric indicators in the Journal Citation Reports-Science Citation Index 2006].

    PubMed

    Gonzalez de Dios, J; Valderrama-Zurian, J C; Gonzalez-Alcaide, G; Sempere, A P; Bolanos-Pizarro, M; Aleixandre-Benavent, R

    Neurological sciences form a multidisciplinary field that produces a wide range of scientific journals. The aim of this study was to perform a scientometric analysis of neurological science journals in the 2006 Journal Citation Reports-Science Citation Index (JCR-SCI) edition. We study the three areas dedicated to neurological sciences (Neurosciences, Clinical Neurology and Neuroimaging) in the 2006 JCR-SCI edition. Bibliometric indicators used are: journals, articles, citations, impact factor (IF), immediacy index, half life and journals with the greatest IF in each specialty. We also perform a special analysis of Spanish neurological journals in JCR-SCI. In the area of Neurosciences we find a total of 200 journals, 27.157 articles, 1.109.784 citations and an average IF of 2,446, the greatest IF belonging to Annu Rev Neurosci (28,533) and Nat Rev Neurosci (23,054); Spanish journals: Neurocirugia and Acta Esp Psiquiatr. The area of Clinical Neurology contains 147 journals, 18.114 articles, 540.364 citations and an average IF of 1,848, the greatest IF belonging to Lancet Neurol (9,479) and Ann Neurol (8,051); Spanish journals: Neurologia and Rev Neurol. The area of Neuroimaging contains 13 journals, 1.747 articles, 49.210 citations and an average IF of 1,298, the greatest IF belonging to Neuroimage (5,559) and Hum Brain Mapp (4,888). We found out a broad representation of neurological journals from the 6,166 journals included in the 2006 JCR-SCI edition. Bibliometric characteristics differ in accordance to the clinical (Clinical Neurology) or experimental (Neurosciences) nature of the area. Even though bibliometric indicators for the four Spanish neurological journals have gradually improve over the previous 5 years, they are still proportionally ranked low in JCR-SCI. Due to significant limitations observed in the IF, we suggest conducting its analysis from a multidimensional bibliometric perspective, and always within its contextual research area.

  8. [Bibliometric study of the activity, structure, and evolution of radiology in Spain].

    PubMed

    Miguel-Dasit, A

    2006-01-01

    From a bibliometric perspective, we reviewed: 1) the scientific activity in the field of diagnostic imaging in Spain, based on the percentage of presentations at the SERAM congresses (1994-1998) later published as articles in scientific journals. The value obtained (15%) is low in comparison with other international congresses, although similar to values for other national congresses in radiology. Both in national and international congresses, collaboration among radiologists from different institutions or countries and between radiologists and clinicians increases the percentage of publications, thus confirming the positive correlation between collaboration and scientific productivity. 2) We also examined the relationship between scientific productivity and the hierarchical structure of Spanish radiology departments (resident, associate, section chief, and department chief). Hierarchical groupings with the participation of residents were found to be more stable from year to year in scientific production, and the group residents + associates had the highest percentage of authorship (21%). 3) Finally, we reviewed the literature to assess the visibility and dissemination of the journal Radiología, estimating the impact factor that the journal would obtain if it were included in the Journal Citation Reports (JRC) database. We emphasize the importance of the inclusion of Radiología both in Medline, the best known and most widely used source of information in the health sciences, and in the JCR.

  9. Bibliometric study of radiation application on microdose useful for new drug development.

    PubMed

    Komoda, Fumio; Suzuki, Akiko; Yanagisawa, Kazuaki; Inoue, Tomio

    2009-12-01

    In spite of the sharp increase in both private and government R&D fund, the number of newly approved medicines for market had decreased since the 1990s. This is attributed to a large extent to the bottleneck in the critical path arising from the great disparity between animal model in pre-clinical trial and human model in clinical trial. This bottleneck may be expected to be gotten rid of by change in paradigm of drug development based on microdosing, which is enabled by radiation-related imaging technology. However, this is impossible without being accompanied by interdisciplinary joint researches, in which clinical investigators belonging to medical schools or hospitals play the most decisive role. In this article, authors verify based on bibliometrics that Japan has not employed the opportunity for revitalizing drug research activities because Japanese researchers' attitude toward radiation technology may not be so positive in comparison with the US, and because the role which clinical investigators play in the phase of pre-clinical trial is smaller in Japan than in the US.

  10. Usage Bibliometrics

    NASA Astrophysics Data System (ADS)

    Kurtz, Michael J.; Bollen, Johan

    2010-01-01

    Scholarly usage data provides unique opportunities to address the known shortcomings of citation analysis. However, the collection, processing and analysis of usage data remains an area of active research. This article provides a review of the state-of-the-art in usage-based informetric, i.e. the use of usage data to study the scholarly process.

  11. Are Quantitative Measures of Academic Productivity Correlated with Academic Rank in Plastic Surgery? A National Study.

    PubMed

    Susarla, Srinivas M; Lopez, Joseph; Swanson, Edward W; Miller, Devin; O'Brien-Coon, Devin; Zins, James E; Serletti, Joseph M; Yaremchuk, Michael J; Manson, Paul N; Gordon, Chad R

    2015-09-01

    The purpose of this study was to investigate the correlation between quantitative measures of academic productivity and academic rank among full-time academic plastic surgeons. Bibliometric indices were computed for all full-time academic plastic surgeons in the United States. The primary study variable was academic rank. Bibliometric predictors included the Hirsch index, I-10 index, number of publications, number of citations, and highest number of citations for a single publication. Descriptive, bivariate, and correlation analyses were computed. Multiple comparisons testing was used to calculate adjusted associations for subgroups. For all analyses, a value of p < 0.05 was considered significant. The cohort consisted of 607 plastic surgeons across 91 Accreditation Council for Graduate Medical Education-approved programs. Of them, 4.1 percent were instructors/lecturers, 43.7 percent were assistant professors, 22.1 percent were associate professors, 25.7 percent were professors, and 4.4 percent were endowed professors. Mean values were as follows: Hirsch index, 10.2 ± 9.0; I-10 index, 17.2 ± 10.2; total number of publications, 45.5 ± 69.4; total number of citations, 725.0 ± 1448.8; and highest number of citations for a single work, 117.8 ± 262.4. Correlation analyses revealed strong associations of the Hirsch index, I-10 index, number of publications, and number of citations with academic rank (rs = 0.62 to 0.64; p < 0.001). Academic rank in plastic surgery is strongly correlated with several quantitative metrics of research productivity. Although academic promotion is the result of success in multiple different areas, bibliometric measures may be useful adjuncts for assessment of research productivity.

  12. Scientific workflows for bibliometrics.

    PubMed

    Guler, Arzu Tugce; Waaijer, Cathelijn J F; Palmblad, Magnus

    Scientific workflows organize the assembly of specialized software into an overall data flow and are particularly well suited for multi-step analyses using different types of software tools. They are also favorable in terms of reusability, as previously designed workflows could be made publicly available through the myExperiment community and then used in other workflows. We here illustrate how scientific workflows and the Taverna workbench in particular can be used in bibliometrics. We discuss the specific capabilities of Taverna that makes this software a powerful tool in this field, such as automated data import via Web services, data extraction from XML by XPaths, and statistical analysis and visualization with R. The support of the latter is particularly relevant, as it allows integration of a number of recently developed R packages specifically for bibliometrics. Examples are used to illustrate the possibilities of Taverna in the fields of bibliometrics and scientometrics.

  13. A bibliometric analysis of evaluative medical education studies: characteristics and indexing accuracy.

    PubMed

    Sampson, Margaret; Horsley, Tanya; Doja, Asif

    2013-03-01

    To determine the characteristics of medical education studies published in general and internal medicine (GIM) and medical education journals, and to analyze the accuracy of their indexing. The authors identified the five GIM and five medical education journals that published the most articles indexed in MEDLINE as medical education during January 2001 to January 2010. They searched Ovid MEDLINE for evaluative medical education studies published in these journals during this period and classified them as quantitative or qualitative studies according to MEDLINE indexing. They also examined themes and learner levels targeted. Using a random sample of records, they assessed the accuracy of study-type indexing. Of 4,418 records retrieved, 3,853 (87.2%) were from medical education journals and 565 (12.3%) were from GIM journals. Qualitative studies and program evaluations were more prevalent within medical education journals, whereas GIM journals published a higher proportion of clinical trials and systematic reviews (χ=74.28, df=3, P<.001). Medical education journals had a concentration of studies targeting medical students, whereas GIM journals had a concentration targeting residents; themes were similar. The authors confirmed that 170 (56.7%) of the 300 sampled articles were correctly classified in MEDLINE as evaluative studies. The majority of the identified evaluative studies were published in medical education journals, confirming the integrity of medical education as a specialty. Findings concerning the study types published in medical education versus GIM journals are important for medical education researchers who seek to publish outside the field's specialty journals.

  14. Trends in scientific activity addressing transmissible spongiform encephalopathies: a bibliometric study covering the period 1973–2002

    PubMed Central

    Sanz-Casado, Elías; Ramírez-de Santa Pau, Margarita; Suárez-Balseiro, Carlos A; Iribarren-Maestro, Isabel; de Pedro-Cuesta, Jesús

    2006-01-01

    Background The purpose of this study is to analyse the trends in scientific research on transmissible spongiform encephalopathies by applying bibliometric tools to the scientific literature published between 1973 and 2002. Methods The data for the study were obtained from Medline database, in order to determine the volume of scientific output in the above period, the countries involved, the type of document and the trends in the subject matters addressed. The period 1973–2002 was divided in three sub-periods. Results We observed a significant growth in scientific production. The percentage of increase is 871.7 from 1973 to 2002. This is more evident since 1991 and particularly in the 1996–2001 period. The countries found to have the highest output were the United States, the United Kingdom, Japan, France and Germany. The evolution in the subject matters was almost constant in the three sub-periods in which the study was divided. In the first and second sub-periods, the subject matters of greatest interest were more general, i.e Nervous system or Nervous system diseases, Creutzfeldt-Jakob disease, Scrapie, and Chemicals and Drugs, but in the last sub-period, some changes were observed because the Prion-related matters had the greatest presence. Collaboration among authors is small from 1973 to 1992, but increases notably in the third sub-period, and also the number of authors and clusters formed. Some of the authors, like Gajdusek or Prusiner, appear in the whole period. Conclusion The study reveals a very high increase in scientific production. It is related also with the beginnings of research on bovine spongiform encephalopathy and variant Creutzfeldt-Jakob disease, with the establishment of progressive collaboration relationships and a reflection of public health concerns about this problem. PMID:17026743

  15. Trends in matrix metalloproteinase research from 1986-2007: a bibliometric study.

    PubMed

    Robert, Claude; Wilson, Concepción S; Gaudy, Jean-François; Hornebeck, William; Arreto, Charles-Daniel

    2010-10-01

    Using the SCI-expanded database, this study provides a quantitative description of the development of the research involving matrix metalloproteinase (MMP) over a period of 20 years. From 1986 to 2007 the scientific literature related to MMP increased sevenfold (397 papers in 1986-1987 and 2834 in 2006-2007). The number of countries participating in MMP-related research doubled during this period (33 in 1986-1987 to 67 in 2006-2007), and the USA continually remained the leader. Several industrialized nations (Japan, Germany, UK, Canada, and France) also continuously played important roles, with some emerging Asian countries joining the top 10 most productive countries in 2006-2007: China (ranked 5th), South Korea (6th), and Taiwan (10th). The MMP-related literature was distributed among a continuously growing number of journals (188 in 1986-1987, 527 in 1996-1997, and 913 in 2006-2007) and The Journal of Biological Chemistry remained the most prolific throughout the entire period. The development of the research involving MMPs during the past two decades was also characterized by a progressive transfer of interest from basic research to clinical medicine; cell biology and pharmacology were important routes of investigation generally pursued by researchers. Journals dedicated to oncology have progressively risen to the top 8 most prolific journals during the 20 year period analyzed.

  16. Bibliometrics as politics: the case of emerging disciplines.

    PubMed

    Traynor, Michael

    2011-03-01

    Academic nurses are increasingly turning to bibliometrics to assess the state and status of research publication in nursing in countries around the world. Early bibliometric studies were carried out by Cattell as part of a project to advance research in psychology in the early decades of the 20th century. There are some echoes in nursing's moves to increase its standing over the last 40 years. The interpretation of bibliometric studies can reveal embedded values about academic disciplinary activity and normative views of scientific work. Patterns of publishing by nurse academics appear increasingly to resemble those in biomedicine as a whole.

  17. What Is Bibliometrics and Why Should You Care?

    SciTech Connect

    McBurney, Melissa K. ); Novak, Pamela L. )

    2002-09-17

    When we help an author publish a book or journal article, is that the end of the job? Viewed in the aggregate, a company's publications represent one of its greatest business assets. Can professionals in the information and communication fields help their company understand the return on its investment in publishing? The field of bibliometrics studies publication patterns by using quantitative analysis and statistics. Bibliometrics can be either descriptive, such as looking at how many articles your organization has published, or evaluative, such as using citation analysis to look at how those articles influenced subsequent research by others. Counting publications can be useful for doing some comparisons, but citation analysis allows you to look at the impact those articles have had on others by determining how often they are cited. Citation analysis can also show what journals, organizations, and even countries have high impact in different fields of research. The Institute for Scientific Information (ISI) has been a leader in the citation analysis field since 1961, when ISI published the first Science Citation Index. Pacific Northwest National Laboratory has been using data from ISI for both descriptive and evaluative purposes. This data is used to track what the researchers at the Laboratory are writing and then comparing research groups within the organization over a period of years to identify trends and opportunities. PNNL has also used citation analysis to explore what organizations and academic institutions are doing research in certain fields for partnering opportunities. We have realized that the electronic system PNNL uses to approve and track its publications contains very valuable bibliometric data that can be used to make decisions about business directions for the company.

  18. [Bibliometrics of woody medical plants in China].

    PubMed

    Zhang, Guoquan; Si, Jinping; Zhu, Yuqiu

    2010-03-01

    Using the theory and method of bibliometrics, this paper made statistical analysis on the research papers of 16 main woody medical plants published in the period of 1998-2007, from aspects of years distribution, journals distribution, themes distribution, authors distribution and research institutes distribution, and so on. The results showed the studies, status quto and development potential of woody medical plants.

  19. Climate Change Research in View of Bibliometrics

    PubMed Central

    Haunschild, Robin; Bornmann, Lutz; Marx, Werner

    2016-01-01

    This bibliometric study of a large publication set dealing with research on climate change aims at mapping the relevant literature from a bibliometric perspective and presents a multitude of quantitative data: (1) The growth of the overall publication output as well as (2) of some major subfields, (3) the contributing journals and countries as well as their citation impact, and (4) a title word analysis aiming to illustrate the time evolution and relative importance of specific research topics. The study is based on 222,060 papers (articles and reviews only) published between 1980 and 2014. The total number of papers shows a strong increase with a doubling every 5–6 years. Continental biomass related research is the major subfield, closely followed by climate modeling. Research dealing with adaptation, mitigation, risks, and vulnerability of global warming is comparatively small, but their share of papers increased exponentially since 2005. Research on vulnerability and on adaptation published the largest proportion of very important papers (in terms of citation impact). Climate change research has become an issue also for disciplines beyond the natural sciences. The categories Engineering and Social Sciences show the strongest field-specific relative increase. The Journal of Geophysical Research, the Journal of Climate, the Geophysical Research Letters, and Climatic Change appear at the top positions in terms of the total number of papers published. Research on climate change is quantitatively dominated by the USA, followed by the UK, Germany, and Canada. The citation-based indicators exhibit consistently that the UK has produced the largest proportion of high impact papers compared to the other countries (having published more than 10,000 papers). Also, Switzerland, Denmark and also The Netherlands (with a publication output between around 3,000 and 6,000 papers) perform top—the impact of their contributions is on a high level. The title word analysis shows

  20. Climate Change Research in View of Bibliometrics.

    PubMed

    Haunschild, Robin; Bornmann, Lutz; Marx, Werner

    2016-01-01

    This bibliometric study of a large publication set dealing with research on climate change aims at mapping the relevant literature from a bibliometric perspective and presents a multitude of quantitative data: (1) The growth of the overall publication output as well as (2) of some major subfields, (3) the contributing journals and countries as well as their citation impact, and (4) a title word analysis aiming to illustrate the time evolution and relative importance of specific research topics. The study is based on 222,060 papers (articles and reviews only) published between 1980 and 2014. The total number of papers shows a strong increase with a doubling every 5-6 years. Continental biomass related research is the major subfield, closely followed by climate modeling. Research dealing with adaptation, mitigation, risks, and vulnerability of global warming is comparatively small, but their share of papers increased exponentially since 2005. Research on vulnerability and on adaptation published the largest proportion of very important papers (in terms of citation impact). Climate change research has become an issue also for disciplines beyond the natural sciences. The categories Engineering and Social Sciences show the strongest field-specific relative increase. The Journal of Geophysical Research, the Journal of Climate, the Geophysical Research Letters, and Climatic Change appear at the top positions in terms of the total number of papers published. Research on climate change is quantitatively dominated by the USA, followed by the UK, Germany, and Canada. The citation-based indicators exhibit consistently that the UK has produced the largest proportion of high impact papers compared to the other countries (having published more than 10,000 papers). Also, Switzerland, Denmark and also The Netherlands (with a publication output between around 3,000 and 6,000 papers) perform top-the impact of their contributions is on a high level. The title word analysis shows that

  1. Plethora or paucity: a systematic search and bibliometric study of the application and design of qualitative methods in nursing research 2008-2010.

    PubMed

    Ball, Elaine; McLoughlin, Moira; Darvill, Angela

    2011-04-01

    Qualitative methodology has increased in application and acceptability in all research disciplines. In nursing, it is appropriate that a plethora of qualitative methods can be found as nurses pose real-world questions to clinical, cultural and ethical issues of patient care (Johnson, 2007; Long and Johnson, 2007), yet the methods nurses readily use in pursuit of answers remains under intense scrutiny. One of the problems with qualitative methodology for nursing research is its place in the hierarchy of evidence (HOE); another is its comparison to the positivist constructs of what constitutes good research and the measurement of qualitative research against this. In order to position and strengthen its evidence base, nursing may well seek to distance itself from a qualitative perspective and utilise methods at the top of the HOE; yet given the relation of qualitative methods to nursing this would constrain rather than broaden the profession in search of answers and an evidence base. The comparison between qualitative and quantitative can be both mutually exclusive and rhetorical, by shifting the comparison this study takes a more reflexive position and critically appraises qualitative methods against the standards set by qualitative researchers. By comparing the design and application of qualitative methods in nursing over a two year period, the study examined how qualitative stands up to independent rather than comparative scrutiny. For the methods, a four-step mixed methods approach newly constructed by the first author was used to define the scope of the research question and develop inclusion criteria. 2. Synthesis tables were constructed to organise data, 3. Bibliometrics configured data. 4. Studies selected for inclusion in the review were critically appraised using a critical interpretive synthesis (Dixon-Woods et al., 2006). The paper outlines the research process as well as findings. Results showed of the 240 papers analysed, 27% used ad hoc or no

  2. Intravenous Lipid Emulsion as an Antidote for the Treatment of Acute Poisoning: A Bibliometric Analysis of Human and Animal Studies.

    PubMed

    Zyoud, Sa'ed H; Waring, W Stephen; Al-Jabi, Samah W; Sweileh, Waleed M; Rahhal, Belal; Awang, Rahmat

    2016-11-01

    In recent years, there has been increasing interest in the role of intravenous lipid formulations as potential antidotes in patients with severe cardiotoxicity caused by drug toxicity. The aim of this study was to conduct a comprehensive bibliometric analysis of all human and animal studies featuring lipid emulsion as an antidote for the treatment of acute poisoning. The Scopus database search was performed on 5 February 2016 to analyse the research output related to intravenous lipid emulsion as an antidote for the treatment of acute poisoning. Research indicators used for analysis included total number of articles, date (year) of publication, total citations, value of the h-index, document types, countries of publication, journal names, collaboration patterns and institutions. A total of 594 articles were retrieved from Scopus database for the period of 1955-2015. The percentage share of global intravenous lipid emulsion research output showed that research output was 85.86% in 2006-2015 with yearly average growth in this field of 51 articles per year. The USA, United Kingdom (UK), France, Canada, New Zealand, Germany, Australia, China, Turkey and Japan accounted for 449 (75.6%) of all the publications. The total number of citations for all documents was 9,333, with an average of 15.7 citations per document. The h-index of the retrieved documents for lipid emulsion research as antidote for the treatment of acute poisoning was 49. The USA and the UK achieved the highest h-indices, 34 and 14, respectively. New Zealand produced the greatest number of documents with international collaboration (51.9%) followed by Australia (50%) and Canada (41.4%) out of the total number of publications for each country. In summary, we found an increase in the number of publications in the field of lipid emulsion after 2006. The results of this study demonstrate that the majority of publications in the field of lipid emulsion were published by high-income countries. Researchers from

  3. Bibliometrics: From Curiosity to Convention.

    ERIC Educational Resources Information Center

    White, Emilie C.

    1985-01-01

    Reports on applications of bibliometrics (measurement of book or compositional entities according to methods that yield comparable results) in the field of information science. Highlights include quantification and qualification, Bradford's Law of Scattering, applications and classifications of citation analysis, and bibliometrics in library…

  4. Bibliometric analysis of the orthopedic literature.

    PubMed

    Hui, Zhaoyang; Yi, Zhongmei; Peng, Jun

    2013-10-01

    Bibliometric indicators are used to assess research performance. The goal of this study was to explore publication output to construct a picture of orthopedics that may be beneficial to researchers and orthopedic specialists. All orthopedics articles published in 61 journals from 2000 to 2011 were retrieved from the Science Citation Index Expanded database. The numbers of articles, citations, authors, institutions, and journals were analyzed and subjected to quantitative and qualitative comparisons. The number of published orthopedics articles increased between 2000 and 2011. Articles published by authors from the United States always ranked first in number, although the United States' share is decreasing in the world literature. Authors from the United States published the most-cited articles and the most articles in journals with top-10 impact factors; moreover, the United States also had the greatest share of experts and highly ranked institutions. The United Kingdom, Germany, and Japan were always within the world's top 4 in terms of numbers of articles and citations. The shares of Germany, South Korea, and China among total orthopedics articles increased, especially that of China. In 2011, China ranked the fifth in the world, with its world share increasing from 0.64% in 2000 to 5.05% in 2011. However, China lags behind in average citations per article, top research institutions, and most prolific authors. According to the total citations per article, the University of Pittsburgh, Harvard University, and the Hospital for Special Surgery were the most prolific institutions. Copyright 2013, SLACK Incorporated.

  5. Bibliometric indicators for evaluating the quality of scientifc publications.

    PubMed

    Joshi, Medha A

    2014-03-01

    Evaluation of quality and quantity of publications can be done using a set of statistical and mathematical indices called bibliometric indicators. Two major categories of indicators are (1) quantitative indicators that measure the research productivity of a researcher and (2) performance indicators that evaluate the quality of publications. Bibliometric indicators are important for both the individual researcher and organizations. They are widely used to compare the performance of the individual researchers, journals and universities. Many of the appointments, promotions and allocation of research funds are based on these indicators. This review article describes some of the currently used bibliometric indicators such as journal impact factor, crown indicator, h-index and it's variants. It is suggested that for comparison of scientific impact and scientific output of researchers due consideration should be given to various factors affecting theses indicators.

  6. A negative trend of biomedical research in Libya: a bibliometric study.

    PubMed

    Benamer, Hani T S; Bredan, Amin; Bakoush, Omran

    2009-09-01

    It is well established that Libya is lagging behind its peers in biomedical research. The aim of this study is to analyse all the original biomedical publications affiliated with Libya from 1973 to 2007. PubMed and the Science Citation Index Expanded were searched for 'original research' biomedical studies affiliated with Libya. The generated data were hand searched and 329 'original research' studies were included in the analysis. The first study was published in 1973. Publication rate peaked to an average of 15.2 studies per year during 1986-1996 and dropped to an average of 8.8 studies per year during 1997-2007. Of 166 first authors; 41% were Libyans and 59% were expatriates. The latter contributed 104 studies between 1986 and 1996 and 36 studies between 1997 and 2007, while the Libyans contributed 63 and 61 studies in the two respective periods. Authors affiliated with Benghazi produced 67% of the published studies, while authors from Tripoli produced 30% and other medical schools, hospitals and research centres from other Libyan cities produced only 3%. This study showed a decline in biomedical research publication in Libya. We propose that the lack of a research culture among the Libyan medical professionals is one of the factors contributing to this decline, which coincided with the departure of expatriate doctors from Libya. Raising awareness of the importance of research and improving research skills among Libyan medical professionals may help to reverse the current trend.

  7. Evidence Base of Clinical Studies on Tai Chi: A Bibliometric Analysis

    PubMed Central

    Yang, Guo-Yan; Zhang, Yan; Li, Meng-Ling; Zhu, Yu-Ting; Luo, Jing; Cheng, Yan-Jun; Li, Wen-Yuan; Wayne, Peter M.; Liu, Jian-Ping

    2015-01-01

    Background The safety and health benefits of Tai Chi mind-body exercise has been documented in a large number of clinical studies focused on specific diseases and health conditions. The objective of this systematic review is to more comprehensively summarize the evidence base of clinical studies of Tai Chi for healthcare. Methods and Findings We searched for all types of clinical studies on Tai chi in PubMed, the Cochrane Library and four major Chinese electronic databases from their inception to July 2013. Data were analyzed using SPSS17.0 software. A total of 507 studies published between 1958 and 2013 were identified, including 43 (8.3%) systematic reviews of clinical studies, 255 (50.3%) randomized clinical trials, 90 (17.8%) non-randomized controlled clinical studies, 115 (22.7%) case series and 4 (0.8%) case reports. The top 10 diseases/conditions was hypertension, diabetes, osteoarthritis, osteoporosis or osteopenia, breast cancer, heart failure, chronic obstructive pulmonary disease, coronary heart disease, schizophrenia, and depression. Many healthy participants practiced Tai Chi for the purpose of health promotion or preservation. Yang style Tai Chi was the most popular, and Tai Chi was frequently practiced two to three 1-hour sessions per week for 12 weeks. Tai Chi was used alone in more than half of the studies (58.6%), while in other studies Tai Chi was applied in combination with other therapies including medications, health education and other physical therapies. The majority of studies (94.1%) reported positive effects of Tai Chi, 5.1% studies reported uncertain effects and 0.8% studies reported negative effects. No serious adverse events related to Tai Chi were reported. Conclusions The quantity and evidence base of clinical studies on Tai Chi is substantial. However, there is a wide variation in Tai Chi intervention studied and the reporting of Tai Chi intervention needs to be improved. Further well-designed and reported studies are recommended to

  8. [Bibliometric analysis of scientific articles on epidemiological study of burns in China].

    PubMed

    Cheng, W F; Shen, Z A; Zhao, D X; Li, D W; Shang, Y R

    2017-04-20

    Objective: To analyze the current status of epidemiological study of burns in China, and to explore the related strategies. Methods: Retrospective or cross-sectional scientific articles in Chinese or English on epidemiological study of burns in China published from January 2005 to December 2015 were systemically retrieved from 4 databases. The databases include PubMed, Embase, China Biology Medicine disc, and Chinese Journals Full-text Database. From the results retrieved, data with regard to publication year, journal distribution, number of institutions participated in the study, affiliation of the first author and its location, and admission time span and age of patients in all the scientific articles were collected. Furthermore, the definition of age range and the grouping method of age of pediatric patients in English articles on epidemiological study of pediatric burns of China were recorded. Data were processed with descriptive statistical analysis. Results: A total of 256 scientific articles conforming to the study criteria were retrieved, among which 214 (83.59%) articles were in Chinese, and 42 (16.41%) articles were in English; 242 (94.53%) articles were retrospective studies, and 14 (5.47%) articles were cross-sectional studies. During the 11 years, the number of the relevant articles was fluctuant on the whole. The scientific articles were published in 130 journals, with 42 English articles in source journals for SCIENCE CITATION INDEX EXPANDED-JOURNAL LIST, accounting for 16.41%, and 116 Chinese articles in Source Journal for Chinese Scientific and Technical Papers, accounting for 45.31%. Totally 215 (83.98%) articles were single-center studies, and 29 (11.33%) articles were multicenter studies which were conducted by three or more centers. The number of affiliations of the first author of articles was 161 in total. The top 10 institutions regarding the article publishing number published 58 articles, accounting for 22.66%. Scientific articles on

  9. Bibliometric study of articles published in a Brazilian journal of pediatric dentistry.

    PubMed

    Poletto, Vanessa Ceolin; Faraco Junior, Italo Medeiros

    2010-01-01

    This cross-sectional study aimed at evaluating the abstracts of all articles published in the 'Jornal Brasileiro de Odontopediatria e Odontologia do Bebê' in order to collect data on the study design used, the most researched topics and the Brazilian states with the highest scientific production. Copies were made of the abstracts of each article, totaling 572 abstracts. Data categorization was done by two trained and independent reviewers. The results showed that the most used study design were case report (33%) and cross-sectional study (30%). On the other hand, there were only 2.5% of randomized clinical trials and no systematic review or meta-analysis. The most researched topics were cariology (15%) and restorative dentistry / dental materials (10%). The state with the greatest number of publications was São Paulo (40%), followed by Rio de Janeiro (17%). It was concluded that the majority of the articles published referred to studies with a low potential to establish scientific evidence, indicating a need for conducting research based on better quality methodology. Moreover, it was found that the assessed literature reflected the trends observed in the clinical practice of Pediatric Dentistry in Brazil.

  10. The explicit mentioning of reporting guidelines in urogynecology journals in 2013: A bibliometric study.

    PubMed

    Koch, Marianne; Riss, Paul; Umek, Wolfgang; Hanzal, Engelbert

    2016-03-01

    Poor reporting of research may limit critical appraisal and reproducibility, whereas adherence to reporting guidelines (RG) can guarantee completeness and transparency. We aimed to determine the explicit citing of RGs (CONSORT, PRISMA, STROBE) in urogynecology articles in 2013, the requirements of relevant journals and a potential difference between urogynecology and general gynecology journals. All urogynecologic articles published between January and December 2013 in the journals NAU, IUJ, FPMRS, GREEN, AJOG, and BJOG were included. Issues were searched for systematic reviews, RCTs, cohort studies, case-control studies and cross-sectional studies. Each electronic article was searched for the term PRISMA, CONSORT, or STROBE according to the study design. Instructions to Authors of the six journals were screened for requirement of using RGs. We included 296 articles (243 observational studies, 40 RCTs, and 13 systematic reviews). The use of PRISMA guidelines was explicitly declared in 54% of systematic reviews, CONSORT guidelines were referenced in 25% of RCTs and STROBE in 1.2% of observational studies. The use of CONSORT is required by all journals except FPMRS. PRISMA and STROBE are only compulsory in the journals GREEN, AJOG, and BJOG. The overall rate of explicit mentioning of RGs comparing urogynecology and general gynecology journals was 6.7% versus 7.1%, respectively. The explicit mentioning of RGs was on a relatively low level. A slightly higher adherence was recognized among general gynecology journals compared to urogynecology journals. Stronger efforts should be taken to further promote the use of RGs in urogynecology. © 2015 Wiley Periodicals, Inc.

  11. A Bibliometric Study of Scholarly Articles Published by Library and Information Science Authors about Open Access

    ERIC Educational Resources Information Center

    Grandbois, Jennifer; Beheshti, Jamshid

    2014-01-01

    Introduction: This study aims to gain a greater understanding of the development of open access practices amongst library and information science authors, since their role is integral to the success of the broader open access movement. Method: Data were collected from scholarly articles about open access by library and information science authors…

  12. A bibliometric study of scientific literature in Scopus on botanicals for treatment of androgenetic alopecia.

    PubMed

    Rondanelli, Mariangela; Perna, Simone; Peroni, Gabriella; Guido, Davide

    2016-06-01

    In androgenetic alopecia, a number of botanicals are available that can effectively slow or reduce hair loss and inflammation or stimulate partial hair regrowth. The aim of this study was to provide a descriptive overview of the impact and production of literature on botanicals used for androgenetic alopecia and to perform a citation analysis of the related research articles. We searched for "alopecia" OR "androgenetic alopecia" OR "hair loss" AND "Camelia sinensis" OR (and other 15 botanicals) in ARTICLE (Title/Abstract/Keyword) in Scopus database. A total of 29 references, that is, research articles, were retrieved by SCOPUS search, and 93.1% had been published since 2000. The majority (48.3%) describe applications of hair grow stimulants, followed by inhibitors of 5-alpha-reductase applications (27.6%), and studies concerning inhibitors of inflammation (24.1%). The citation analysis revealed a growing interest for this topic and the papers on hair grow stimulants are most cited. Citation trend of inhibition of 5-alpha-reductase articles is growing in the last years. This study has highlighted three important aspects: (1) growing interest for this topic; (2) evidences mainly in hair grow stimulants and recently in the inhibition of 5-alpha-reductase, as demonstrated by article and citation counts across years; (3) in addition, all major studies have been focused on green tea epigallocatechin-3-gallate, Serenoa repens, Citrullus colocynthis and Cuscuta reflexa. © 2015 Wiley Periodicals, Inc.

  13. Hotel Cosmopolitan: A Bibliometric Study of Collaboration at Some European Universities.

    ERIC Educational Resources Information Center

    Melin, Goran; Persson, Olle

    1998-01-01

    This study investigated the collaborative patterns (internal, national, international, and mixed national and international) of 33 Nordic, United Kingdom, and Netherlands universities by analyzing institutionally co-authored articles from Science Citation Index (1993). Found no major difference between universities in articles with internal,…

  14. Three decades of suicide and life-threatening behavior: a bibliometric study.

    PubMed

    Cardinal, Charles

    2008-06-01

    The purpose of this study is to quantify certain characteristics of the articles published in Suicide and Life-Threatening Behavior in three 5-year periods, namely, 1971-1975, 1984-1988, and 1997-2001. The characteristics in question include geographic origin of articles, number of authors per article, number of references listed per article, and number of times an article is cited in the literature. Changes across the three periods in terms of distribution of subjects/participants by age group and gender are also examined. The discussion focuses on explanations for the trends and characteristics that are described.

  15. Finite Element Analysis Generates an Increasing Interest in Dental Research: A Bibliometric Study

    PubMed Central

    Diarra, Abdoulaziz; Mushegyan, Vagan; Naveau, Adrien

    2016-01-01

    Purpose: The purpose was to provide a longitudinal overview of published studies that use finite element analysis in dental research, by using the SCI-expanded database of Web of Science® (Thomson Reuters). Material and Methods: Eighty publications from 1999-2000 and 473 from 2009-2010 were retrieved. This literature grew faster than the overall dental literature. The number of publishing countries doubled. The main journals were American or English, and dealt with implantology. For the top 10 journals publishing dental finite element papers, the mean impact factor increased by 75% during the decade. Results: Finite elements generate an increasing interest from dental authors and publishers worldwide. PMID:27006722

  16. [Scientific production and cancer-related collaboration networks in Peru 2000-2011: a bibliometric study in Scopus and Science Citation Index].

    PubMed

    Mayta-Tristán, Percy; Huamaní, Charles; Montenegro-Idrogo, Juan José; Samanez-Figari, César; González-Alcaide, Gregorio

    2013-03-01

    A bibliometric study was carried out to describe the scientific production on cancer written by Peruvians and published in international health journals, as well as to assess the scientific collaboration networks. It included articles on cancer written in Peru between the years 2000 and 2011 and published in health journals indexed in SCOPUS or Science Citation Index Expanded. In the 358 articles identified, an increase in the production was seen, from 4 articles in 2000 to 57 in 2011.The most studied types were cervical cancer (77 publications); breast cancer (53), and gastric cancer (37). The National Institute of Neoplastic Diseases (INEN) was the most productive institution (121 articles) and had the highest number of collaborations (180 different institutions). 52 clinical trials were identified, 29 of which had at least one author from INEN. We can conclude that, cancer research is increasing in Peru, the INEN being the most productive institution, with an important participation in clinical trials.

  17. The Changing Landscape of Neuroscience Research, 2006–2015: A Bibliometric Study

    PubMed Central

    Yeung, Andy Wai Kan; Goto, Tazuko K.; Leung, W. Keung

    2017-01-01

    Background: It is beneficial to evaluate changes in neuroscience research field regarding research directions and topics over a defined period. Such information enables stakeholders to quickly identify the most influential research and incorporate latest evidence into research-informed education. To our knowledge, no study reported changes in neuroscience literature over the last decade. Therefore, the current study determined research terms with highest citation scores, compared publication shares of research areas and contributing countries in this field from 2006 to 2015 and identified the most productive journals. Methods: Data were extracted from Web of Science and Journal Citation Reports (JCR). Only articles and reviews published in journals classified under the JCR “Neurosciences” category over the period of interest were included. Title and abstract fields of each included publication were extracted and analyzed via VOSviewer to identify recurring terms with high relative citation scores. Two term maps were produced for publications over the study period to illustrate the extent of co-occurrence, and the impact of terms was evaluated based on their relative citation scores. To further describe the recent research priority or “hot spots,” 10 terms with the highest relative citation scores were identified annually. In addition, by applying Bradford's law, we identified 10 journals being the most productive journals per annum over the survey period and evaluated their bilbiometric performances. Results: From 2006 to 2015, there were 47 terms involved in the annual lists of top 10 terms with highest relative citation scores. The most frequently recurring terms were autism (8), meta-analysis (7), functional connectivity (6), default mode network (4) and neuroimaging (4). Neuroscience research related to psychology and behavioral sciences showed an increase in publication share over the survey period, and China has become one of the major contributors to

  18. The Changing Landscape of Neuroscience Research, 2006-2015: A Bibliometric Study.

    PubMed

    Yeung, Andy Wai Kan; Goto, Tazuko K; Leung, W Keung

    2017-01-01

    Background: It is beneficial to evaluate changes in neuroscience research field regarding research directions and topics over a defined period. Such information enables stakeholders to quickly identify the most influential research and incorporate latest evidence into research-informed education. To our knowledge, no study reported changes in neuroscience literature over the last decade. Therefore, the current study determined research terms with highest citation scores, compared publication shares of research areas and contributing countries in this field from 2006 to 2015 and identified the most productive journals. Methods: Data were extracted from Web of Science and Journal Citation Reports (JCR). Only articles and reviews published in journals classified under the JCR "Neurosciences" category over the period of interest were included. Title and abstract fields of each included publication were extracted and analyzed via VOSviewer to identify recurring terms with high relative citation scores. Two term maps were produced for publications over the study period to illustrate the extent of co-occurrence, and the impact of terms was evaluated based on their relative citation scores. To further describe the recent research priority or "hot spots," 10 terms with the highest relative citation scores were identified annually. In addition, by applying Bradford's law, we identified 10 journals being the most productive journals per annum over the survey period and evaluated their bilbiometric performances. Results: From 2006 to 2015, there were 47 terms involved in the annual lists of top 10 terms with highest relative citation scores. The most frequently recurring terms were autism (8), meta-analysis (7), functional connectivity (6), default mode network (4) and neuroimaging (4). Neuroscience research related to psychology and behavioral sciences showed an increase in publication share over the survey period, and China has become one of the major contributors to

  19. Trends of triple negative breast cancer research (2007-2015): A bibliometric study.

    PubMed

    Wang, Yiran; Zhai, Xiao; Liu, Chuan; Wang, Ning; Wang, Yajie

    2016-11-01

    Triple negative breast cancer (TNBC) is an aggressive breast cancer subtype. However, there have been limited data to evaluate the trend of TNBC research. This study aims to investigate the trend of TNBC research and compare the contribution of research from different regions, organizations, and authors. TNBC-related publications from 2007 to 2015 were retrieved from the Web of Science database. Excel 2013 (Redmond, Washington, USA), GraphPad Prism 5 (GraphPad Prism Software Inc., San Diego, CA), and VOSviewer (Leiden University, Leiden, Netherlands) software were used to analyze the trend of TNBC research. This article does not contain any studies with human participants or animals performed by any of the authors. A total of 1695 papers were identified and were cited 34,078 times with a time limit of May 27, 2016. The United States accounted for 43.10% of the articles, 57.59% of the citations, and the highest H-index (64). China ranked second in total number of articles, but seventh in citation frequency (1998) and ninth in H-index (21). The journal Breast Cancer Research and Treatment had the highest number of publications. The author, Narod SA, has published the most papers in this field (30). The keyword "receptor" was mentioned the most, 1489 times, and the word "myeloid cell leukemia-1 (MCL-1)" was the latest hot spot by 2015. Literature growth related to TNBC is expanding rapidly in recent years. The quality of the articles from China still requires improvement. Newest progress of the TNBC research may be released by the journal Breast Cancer Research and Treatment first. Narod SA, Gonzalez-Angulo AM, and Hortobagyi GN may be good candidates for collaborative research in this field. MCL-1 is an emerging topic that should be closely observed.

  20. Adherence to ICCS nomenclature guidelines in subsequent literature: a bibliometric study.

    PubMed

    Dannaway, Jasan; Ng, Heryanto; Deshpande, Aniruddh V

    2013-09-01

    Since the publication of the 2006 International Children's Continence Society (ICCS) guidelines on terminologies for lower urinary tract dysfunction in children, little is known of their impact. In this study, we aim to quantify the adherence to the guidelines in the published literature, and to examine whether Medical Subject Headings (MeSH) in MEDLINE reflect the recommended "new" ICCS terminology. Seven pairs of pre-specified paired terms (obsolete and recommended by the ICCS) were searched, limited to paediatric literature published between 2002 and 2010. Their use in the literature was compared between the pre-guideline (2002-2005) and post-guideline (2007-2010) period and across geographical regions. MeSH in MEDLINE were examined for the use of ICCS preferred terminology. Publications in paediatric urinary incontinence have shown a 49% increase from 2002-2005 to 2007-2010 (55-82 per year). There was about a fourfold increase in the likelihood of usage of ICCS recommended terminologies post ICCS guideline publication (OR: 4.19, 95% CI: 3.04-5.78, P < 0.001). Approximately 25% of the studies published between 2007 and 2010 used obsolete terminologies. Analysis indicated satisfactory uptake for most terms, with the exception of "urotherapy." There was no significant geographical variation in uptake. More than half of the ICCS-recommended terms (4/7) did not appear in the current MeSH indexing tree and scope notes. Overall uptake of recommended terms following release of ICCS terminology guidelines was encouraging although it remains suboptimal for certain terms. Efforts need to be made to improve the current MEDLINE indexing so that MeSH terms reflect terminology recommended by the ICCS. Copyright © 2012 Wiley Periodicals, Inc.

  1. European Non-Communicable Respiratory Disease Research, 2002-13: Bibliometric Study of Outputs and Funding

    PubMed Central

    Wright, John S. F.; Pallari, Elena; Sullivan, Richard

    2016-01-01

    This study was conducted in order to map European research in chronic respiratory diseases (CRDs). It was intended to assist the European Commission and other research funders to identify gaps and overlaps in their portfolios, and to suggest ways in which they could improve the effectiveness of their support and increase the impact of the research on patient care and on the reduction of the incidence of the CRDs. Articles and reviews were identified in the Web of Science on research in six non-communicable respiratory diseases that were published in 2002–13 from 31 European countries. They represented only 0.8% of biomedical research output but these diseases accounted for 4.7% of the European disease burden, as measured by Disability-Adjusted Life Years (DALYs), so the sub-field is seriously under-researched. Europe is prominent in the sub-field and published 56% of the world total, with the UK the most productive and publishing more than France and Italy, the next two countries, combined. Asthma and Chronic Obstructive Pulmonary Disease (COPD) were the diseases with the most publications and the highest citation rates. They also received the most funding, with around two acknowledgments per paper (in 2009–13), whereas cystic fibrosis and emphysema averaged only one. Just over 37% of papers had no specific funding and depended on institutional support from universities and hospitals. PMID:27111670

  2. European Non-Communicable Respiratory Disease Research, 2002-13: Bibliometric Study of Outputs and Funding.

    PubMed

    Begum, Mursheda; Lewison, Grant; Wright, John S F; Pallari, Elena; Sullivan, Richard

    2016-01-01

    This study was conducted in order to map European research in chronic respiratory diseases (CRDs). It was intended to assist the European Commission and other research funders to identify gaps and overlaps in their portfolios, and to suggest ways in which they could improve the effectiveness of their support and increase the impact of the research on patient care and on the reduction of the incidence of the CRDs. Articles and reviews were identified in the Web of Science on research in six non-communicable respiratory diseases that were published in 2002-13 from 31 European countries. They represented only 0.8% of biomedical research output but these diseases accounted for 4.7% of the European disease burden, as measured by Disability-Adjusted Life Years (DALYs), so the sub-field is seriously under-researched. Europe is prominent in the sub-field and published 56% of the world total, with the UK the most productive and publishing more than France and Italy, the next two countries, combined. Asthma and Chronic Obstructive Pulmonary Disease (COPD) were the diseases with the most publications and the highest citation rates. They also received the most funding, with around two acknowledgments per paper (in 2009-13), whereas cystic fibrosis and emphysema averaged only one. Just over 37% of papers had no specific funding and depended on institutional support from universities and hospitals.

  3. [On the proper use of bibliometrics to evaluate physicians and scientists].

    PubMed

    Bach, Jean-François

    2011-06-01

    Quantitative analysis of publications and their citations, a procedure known as bibliometrics, has become increasingly important in the evaluation of scientists and clinicians. In the clinical setting, bibliometrics is used for the calculation of hospital budgets. While bibliometrics is attractive because it rapidly provides numbers that bear a certain relation to scientific productivity, it is often misused. The parameters chosen are questionable and sometimes worthless because of material errors or inappropriate use. More importantly, reducing the activity of a scientist or physician simply to the number of his or her publications or citations, without analyzing the importance and impact of the work itself can lead to serious errors.

  4. [Bibliometric study of the Journal Nutrición Hospitalaria for the period 2001-2005: Part 1, Analysis of the scientific production].

    PubMed

    Casterá, V T; Sanz-Valero, J; Juan-Quilis, V; Wanden-Berghe, C; Culebras, J M; García de Lorenzo y Mateos, A

    2008-01-01

    To assess the scientific activity and information production of the journal Nutrición Hospitalaria, for the period 2001-2005 by means of a Bibliometric study. Cross-sectional descriptive study of the results obtained from the analysis of the articles published in the journal Nutrición Hospitalaria. The data were obtained by consulting the electronic version through the Web. In those cases in which there was a link breakdown, and thus, the inability to have access to the electronic document the printed version was consulted. All the documental possibilities were taken into account with the exception of communications to congresses. A total of 345 articles were published, 187 (54.20%) being original articles. The geographical distribution of the first author was Spanish in 287 articles (83.19%) and Latin American in 27 (7.83%). Most of the articles are from health care centers (172 articles (49.86%)), and the cooperation index being 4.15. Madrid is the most productive province, for both the absolute and adjusted frequencies. The median number of references per article is 18, the mean being 23.52 (95% CI 20.93 - 26.10). The predominant language was Spanish, with 308 articles (89.28%). Nutrición Hospitalaria may be considered as a reference journal regarding information and scientific communication on Nutrition for both the Spanish and Latin American communities. The bibliometric parameters studied compare with those verified for the remaining top of the list Spanish scientific journals on health sciences.

  5. [Bibliometric study of scientific output published by the Revista Panamericana de Salud Pública/Pan American Journal of Public Health from 1997-2012].

    PubMed

    Sanz-Valero, Javier; Casterá, Vicente Tomás; Wanden-Berghe, Carmina

    2014-02-01

    To characterize the scientific output of the Revista Panamericana de Salud Pública/Pan American Journal of Public Health (RPSP) as a scientific publication of reference in the public health sector in the Americas. A descriptive cross-sectional study was conducted based on the articles published in the RPSP from 1997-2012. Bibliometric indicators of productivity (documents published, languages, authorship, and indices of productivity and collaboration); impact (impact factor according to the SciELO Network, Journal Citation Report and SCImago); key words; and bibliographic references, their structure (document type and main nucleus of Bradford) and degree of obsolescence (Burton and Kebler half-life, and Price index), were analyzed. A total of 2 815 articles with a median of 3 authors and 2 institutions per article were published. The percentage of original research articles increased in 2008-2012 compared to 2003-2007 and 1997-2002 (P < 0.001). The predominant language was Spanish, displaced by English in the last 5 years. A total of 88.76% of the key words referred to the Health Sciences Descriptors (DeCS) and had a public health and community orientation related to the Americas. The Burton and Kebler half-life of bibliographic references was 8 years, although it decreased to 5 years in 2012. The Price index was 20.47% and the nucleus of Bradford was made up of 20 mainstream journals. The percentage of self-citation was low (2.07%). The RPSP is an international publication with bibliometric indicators similar to those of the most representative Latin American health science journals, with improvements in the recent years studied that lead it to fully meet international publishing criteria.

  6. Quantitative analysis of PET studies.

    PubMed

    Weber, Wolfgang A

    2010-09-01

    Quantitative analysis can be included relatively easily in clinical PET-imaging protocols, but in order to obtain meaningful quantitative results one needs to follow a standardized protocol for image acquisition and data analysis. Important factors to consider are the calibration of the PET scanner, the radiotracer uptake time and the approach for definition of regions of interests. Using such standardized acquisition protocols quantitative parameters of tumor metabolism or receptor status can be derived from tracer kinetic analysis and simplified approaches such as calculation of standardized uptake values (SUVs).

  7. Dental research in Spain. A bibliometric analysis on subjects, authors and institutions (1993-2012)

    PubMed Central

    Bueno-Aguilera, Felipe; Lucena-Martín, Cristina; Pulgar-Encinas, Rosa

    2016-01-01

    Background Bibliometrics is defined as the use of statistical methods in the analysis of a body of literature to reveal the historical development of subject fields and patterns of authorship, publication, and use. Our objective was to characterize Spanish scientific output in Dentistry through the analysis of Web of Science database in a 20-year period. By means of a bibliometric study documents were statistically analyzed using indicators that showed quantitative and qualitative aspects of the production. Specifically, time course of the scientific production within the time span was analysed, as were the journals where the article was published and the categories of Journal Citation Reports (JCR) in which they belong, thematic areas, authorship, and finally authors and institutions with the highest production in Spain. Material and Methods By means of the design of a specific search strategy previously described in the scientific literature, we recovered all citable documents about Dentistry signed by Spanish researchers and included in the WoS database between 1993 and 2012. Results A total of 3006 documents fulfilled the search criteria, of which 2449 (81.5%) were published in journals within the category Dentistry Oral Surgery and Medicine and 557 (18.5%) within other categories of the JCR. During the four quinquenniums studied, the production increased quantitatively (8.6-fold) and qualitatively. Finally, the universities of Granada and Complutense of Madrid were the institutions with the highest production and most prolific authors. Conclusions The Spanish dental production sharply increased in the last two decades, reaching quantitative and qualitative levels similar to those of the other medical specialties in the country. Key words:Dental research, dentistry, publications, Journal impact factor, bibliometrics, biomedical research, Spanish dental production. PMID:26827056

  8. Advanced Bibliometric Methods To Model the Relationship between Entry Behavior and Networking in Emerging Technological Communities.

    ERIC Educational Resources Information Center

    Debackere, Koenraad; Clarysse, Bart

    1998-01-01

    Technological communities used bibliometric data on 411 plant biotechnology organizations to study the effect of field density and structure of the research and development network. Findings indicate the usefulness of bibliometric data in mapping change in technological communities and in the effects of networking on entry behavior. (PEN)

  9. A bibliometric analysis of two decades of aromatherapy research.

    PubMed

    Koo, Malcolm

    2017-01-18

    Quantitative data are lacking on the profile of published research in aromatherapy. The objective of the study was to investigate the profile of original and review articles under the topic aromatherapy using bibliometric analysis. Articles on aromatherapy, published between 1995 and 2014, were retrieved from the Science Citation Index-Expanded database from the Web of Science. The records extracted were analyzed for citation characteristics, including the distribution of publication years, languages, countries or regions, journals, articles, and authors using HistCite 12.03.17. VOSviewer v.1.61 was used to construct bibliometric diagrams. A total of 549 original and review articles, published in 287 different peer-reviewed journals by 1888 authors, were identified. There was a steady increase in the number of published articles from 1995 to 2014. The majority of the articles was written in English (95.8%) and the United States was the leading country in the total number of published articles (n = 107, 19.5%) Journal of Alternative and Complementary Medicine published the greatest number of articles on the topic (n = 31, 5.6%). The article that received the greatest number of citations was published in Complementary Therapies in Medicine. Visualization analysis based on co-occurrences of words in the title and abstract revealed three clusters of research topics, including essential oil, intervention, and complementary medicine. This study provided a systematic overview of productivity and visibility of research work in aromatherapy and the findings could be used for organizing and prioritizing future research efforts in aromatherapy research.

  10. QUANTITATIVE STUDIES OF PROSTATIC SECRETION

    PubMed Central

    Huggins, Charles; Masina, M. H.; Eichelberger, Lillian; Wharton, James D.

    1939-01-01

    A simple isolation of the prostate enabled quantitative collection of prostatic secretion in dogs over periods of months. The secretory stimulant was pilocarpine and 2 similar amounts injected with a 6 hour interval gave smaller amounts at the second testing, suggesting a fatigue effect. The prostate was not absolutely refractory since doubling the amount of alkaloid injected at the second test increased the volume to equal or exceed the preliminary secretion. The depression effect had disappeared at 24 hours. In normal dogs the secretory curves were essentially regular, with occasional prolonged rises or depressions. The amount of secretion did not bear a direct relationship to the weight of the gland in adult dogs. The germinal epithelium of the testis underwent atrophy during the first few weeks of cage life while the prostatic secretion was maintained, showing that the atrophy was differential and did not involve the cells producing the androgenic hormone. The atrophy was reversible and all dogs kept for more than 4 months showed restoration of the germ cells. A few dogs developed atrophy of the germinal cells with cessation of prostatic secretion for many weeks but with final recovery. Removal of the suprarenal glands with suprarenal insufficiency did not produce sterility. The distribution of electrolytes in the prostatic secretion differed from that in the serum-transudate system, although the concentration of osmotically active substances was the same, being made up almost entirely of sodium and chloride. The distribution was not affected by the different physiological procedures used in this study. Protein concentrations were less than 1 per cent. The rate of prostatic atrophy following castration was determined, and cessation of secretion occurred in 7 to 23 days. The restoration of prostatic fluid in castrate dogs following daily injections of testosterone propionate followed a smooth curve to form a plateau which was interrupted occasionally by

  11. Quantitative studies of immunofluorescent staining*

    PubMed Central

    Beutner, Ernst H.; Sepulveda, Marion R.; Barnett, Eugene V.

    1968-01-01

    Reproducible titres of indirect immunofluorescent (IF) staining with antinuclear factor (ANF)-containing sera could be obtained with different antihuman IgG conjugates by quantitative adjustments of their characteristics. Conversely, one ANF yielded a broad range of ANF titre (80-640) upon appropriate adjustments of the conjugate characteristics. The same and related characteristics of the conjugates also afforded a basis for quantitatively defining the conditions under which non-specific staining (NSS) appeared. The salient characteristics of the anti-IgG conjugates include: (1) their strength of antiglobulin (expressed as units/ml of precipitating antibody or μg antibody N/ml); (2) their apparent fluorescein concentration (in μg F/ml); (3) their protein concentration (in mg/ml). Optical and immunologic sensitivity ratios are calculated from these conjugate characteristics. Optical sensitivity (expressed as fluorescein concentration to protein concentration (F/P) ratios), immunological sensitivities (expressed as units/1% protein) and the dilution employed serve to characterize quantitatively anti-IgG conjugates adequately to define their specific and non-specific staining properties. PMID:4179321

  12. Understanding bibliometric parameters and analysis.

    PubMed

    Choudhri, Asim F; Siddiqui, Adeel; Khan, Nickalus R; Cohen, Harris L

    2015-01-01

    Bibliometric parameters have become an important part of modern assessment of academic productivity. These parameters exist for the purpose of evaluating authors (publication count, citation count, h-index, m-quotient, hc-index, e-index, g-index, i-10 [i-n] index) and journals (impact factor, Eigenfactor, article influence score, SCImago journal rank, source-normalized impact per paper). Although in recent years there has been a proliferation of bibliometric parameters, the true meaning and appropriate use of these parameters is generally not well understood. Effective use of existing and emerging bibliometric tools can aid in assessment of academic productivity, including readiness for promotions and other awards. However, if not properly understood, the data can be misinterpreted and may be subject to manipulation. Familiarity with bibliometric parameters will aid in their effective implementation in the review of authors-whether individuals or groups-and journals, as well as their possible use in the promotions review process, maximizing the effectiveness of bibliometric analysis.

  13. Quantitative Studies and the American Revolution

    ERIC Educational Resources Information Center

    Stout, Harry S.

    1976-01-01

    Author states that "...quantitative studies have demonstrated the impossibility of understanding the American Revolution without understanding the society in which it emerged. Combining the quantitative studies of early American social structure with the exploration of popular ideology or culture should...make possible a sense of how revolutionary…

  14. Quantitative Studies and the American Revolution

    ERIC Educational Resources Information Center

    Stout, Harry S.

    1976-01-01

    Author states that "...quantitative studies have demonstrated the impossibility of understanding the American Revolution without understanding the society in which it emerged. Combining the quantitative studies of early American social structure with the exploration of popular ideology or culture should...make possible a sense of how revolutionary…

  15. Automated Research Impact Assessment: A New Bibliometrics Approach

    PubMed Central

    Drew, Christina H.; Pettibone, Kristianna G.; Finch, Fallis Owen; Giles, Douglas; Jordan, Paul

    2016-01-01

    As federal programs are held more accountable for their research investments, The National Institute of Environmental Health Sciences (NIEHS) has developed a new method to quantify the impact of our funded research on the scientific and broader communities. In this article we review traditional bibliometric analyses, address challenges associated with them, and describe a new bibliometric analysis method, the Automated Research Impact Assessment (ARIA). ARIA taps into a resource that has only rarely been used for bibliometric analyses: references cited in “important” research artifacts, such as policies, regulations, clinical guidelines, and expert panel reports. The approach includes new statistics that science managers can use to benchmark contributions to research by funding source. This new method provides the ability to conduct automated impact analyses of federal research that can be incorporated in program evaluations. We apply this method to several case studies to examine the impact of NIEHS funded research. PMID:26989272

  16. Automated Research Impact Assessment: A New Bibliometrics Approach.

    PubMed

    Drew, Christina H; Pettibone, Kristianna G; Finch, Fallis Owen; Giles, Douglas; Jordan, Paul

    2016-03-01

    As federal programs are held more accountable for their research investments, The National Institute of Environmental Health Sciences (NIEHS) has developed a new method to quantify the impact of our funded research on the scientific and broader communities. In this article we review traditional bibliometric analyses, address challenges associated with them, and describe a new bibliometric analysis method, the Automated Research Impact Assessment (ARIA). ARIA taps into a resource that has only rarely been used for bibliometric analyses: references cited in "important" research artifacts, such as policies, regulations, clinical guidelines, and expert panel reports. The approach includes new statistics that science managers can use to benchmark contributions to research by funding source. This new method provides the ability to conduct automated impact analyses of federal research that can be incorporated in program evaluations. We apply this method to several case studies to examine the impact of NIEHS funded research.

  17. The bibliometric analysis of scholarly production: How great is the impact?

    PubMed

    Ellegaard, Ole; Wallin, Johan A

    Bibliometric methods or "analysis" are now firmly established as scientific specialties and are an integral part of research evaluation methodology especially within the scientific and applied fields. The methods are used increasingly when studying various aspects of science and also in the way institutions and universities are ranked worldwide. A sufficient number of studies have been completed, and with the resulting literature, it is now possible to analyse the bibliometric method by using its own methodology. The bibliometric literature in this study, which was extracted from Web of Science, is divided into two parts using a method comparable to the method of Jonkers et al. (Characteristics of bibliometrics articles in library and information sciences (LIS) and other journals, pp. 449-551, 2012: The publications either lie within the Information and Library Science (ILS) category or within the non-ILS category which includes more applied, "subject" based studies. The impact in the different groupings is judged by means of citation analysis using normalized data and an almost linear increase can be observed from 1994 onwards in the non-ILS category. The implication for the dissemination and use of the bibliometric methods in the different contexts is discussed. A keyword analysis identifies the most popular subjects covered by bibliometric analysis, and multidisciplinary articles are shown to have the highest impact. A noticeable shift is observed in those countries which contribute to the pool of bibliometric analysis, as well as a self-perpetuating effect in giving and taking references.

  18. Evolution of three Nobel Prize themes and a Nobel snub theme in chemistry: a bibliometric study with focus on international collaboration.

    PubMed

    Tong, Sichao; Ahlgren, Per

    2017-01-01

    In this study, three chemistry research themes closely associated with the Nobel Prize are bibliometrically analyzed-Ribozyme, Ozone and Fullerene-as well as a research theme in chemistry not associated with the Nobel Prize (a Nobel snub theme): Brunauer-Emmett-Teller equation. We analyze, based on an algorithmically constructed publication-level classification system, the evolution of the four themes with respect to publication volume and international collaboration, using two datasets, one of them a subset of highly cited publications, for each considered time period. The focus of the study is on international collaboration, where co-occurrence of country names in publications is used as a proxy for international collaboration. For all four themes, especially for Brunauer-Emmett-Teller equation, the publication volumes increase considerably from the earliest period to the later periods. The international collaboration rate shows an increasing trend for each theme. For Ozone, Fullerene and Brunauer-Emmett-Teller equation, the international collaboration rate tend to be higher for the highly cited publications compared to full datasets. With regard to the evolution of number of countries per international publication and per highly cited international publication, a vast majority of the distributions are positively skewed, with a large share of publications with two countries. With respect to the last four periods of the study, the concentration to two countries per publication is more pronounced for the Brunauer-Emmett-Teller equation theme compared to the three Nobel Prize themes.

  19. [Bibliometric study of the journal Nutrición Hospitalaria for the period 2001--2005: Part 2, consumption analysis; the bibliographic references].

    PubMed

    Castera, V T; Sanz Valero, J; Juan-Quilis, V; Wanden-Berghe, C; Culebras, J M; García de Lorenzo y Mateos, A

    2008-01-01

    To describe and assess the consumption of the information consulted and cited in the articles published in the journal Nutrición Hospitalaria for the period 2001--2005 by means of bibliometric analysis. Cross-sectional descriptive analysis of the results obtained from the analysis of the lists of bibliographic references of the articles published at Nutrición Hospitalaria. We studied the most cited journals, the signatures index, the type of document referred, the publication language, the distribution of geographical origin, and obsolescence and readiness index. We took into account all types of documents with the exception of Communications to Congresses. 345 articles were published at Nutr Hosp, containing 8,113 bibliographic references, with a median of 18, a maximum of 136 and minimum of 0 BR per article. The mean (rate of publications per published article during the specified period) is 23.52 (95% IC 20.93-26.10) and the mean at 5% is 20.66 per article. The 25th and 75th percentiles are 6 and 32, respectively, the interquartile interval being 26 BR per document. The semi-period of Burton and Kebler is 7 years and the Price Index is 38.18%. The bibliographic references, the consumption of information, of the articles published at Nutrición Hospitalaria present parameters similar to other journals on health science. However, good data on obsolescence are observed, which reveal the good validity of most of the references studied.

  20. Bibliometric analysis of output and impact based on CRIS data: a case study on the registered output of a Dutch university.

    PubMed

    van Leeuwen, Thed N; van Wijk, Erik; Wouters, Paul F

    In this study we combine the registered output of a whole university in the Netherlands with data retrieved from the Web of Science. The initial research question was: is it possible to show the impact of the university in its' full broadness, taking into account the variety of disciplines covered in the research profile of the university? In order to answer this question, we analyzed the output of the university as registered in the CRIS system METIS, over the years 2004-2009. The registration covers a wide variety of scholarly outputs, and these are all taken into account in the analysis. In the study we conduct analyses on the coverage of the output of the university, both from the perspective of the output itself, towards the Web of Science ("external"), as well as from the Web of Science perspective itself ("internal"). This provides us with the necessary information to be able to draw clear conclusions on the validity of the usage of standard bibliometric methodologies in the research assessment of universities with such a research profile.

  1. [Nutrition sciences in Spain in the second half of the twentieth century: a descriptive bibliometric study of the journal Anales de Bromatologia (1949-1993)].

    PubMed

    Bernabeu-Mestre, J; Ureña Alberola, M T; Esplugues Pellicer, J X; Trescastro-López, E M; Galiana-Sánchez, M E; Castelló Botía, I

    2012-11-01

    To analyse the institutionalisation of nutrition sciences in Spain in the second half of the twentieth century, and evaluate the activities of the journal Anales de Bromatología. Descriptive bibliometric study of the original articles. Full names of the authors and the complete article title were recorded. Using key words, each article was assigned by consensus of the researchers to a single main subject in accordance with the thirteen subject areas addressed by the Spanish Society of Bromatology in its meetings. An analysis was conducted of the distribution and trends of general productivity indicators and their characteristics. A total of 917 original articles were published, with a mean of 20.8 papers/year. The subjects for which the highest percentage of articles was recorded were foreign substances in foods, foods of plant origin and nutrition. A total of 874 authors contributed, with a collaboration rate of 2.43 and a transience rate of 70.1%. Distribution of the number of authors per article was close to that indicated by Lotka's law of scientific productivity. The top twelve producers, predominantly women, participated in 49.9% of the articles published. The journal showed low productivity and was of an endogamous nature, with a predominance of authors related to the School of Bromatology in the Faculty of Pharmacy, at the Complutense University. The subjects addressed reflected the demands of the nutrition transition in Spain.

  2. The 100 most-cited original articles in cardiac computed tomography: A bibliometric analysis.

    PubMed

    O'Keeffe, Michael E; Hanna, Tarek N; Holmes, Davis; Marais, Olivia; Mohammed, Mohammed F; Clark, Sheldon; McLaughlin, Patrick; Nicolaou, Savvas; Khosa, Faisal

    2016-01-01

    Bibliometric analysis is the application of statistical methods to analyze quantitative data about scientific publications. It can evaluate research performance, author productivity, and manuscript impact. To the best of our knowledge, no bibliometric analysis has focused on cardiac computed tomography (CT). The purpose of this paper was to compile a list of the 100 most-cited articles related to cardiac CT literature using Scopus and Web of Science (WOS). A list of the 100 most-cited articles was compiled by order of citation frequency, as well a list of the top 10 most-cited guideline and review articles and the 20 most-cited articles of the years 2014-2015. The database of 100 most-cited articles was analyzed to identify characteristics of highly cited publications. For each manuscript, the number of authors, study design, size of patient cohort and departmental affiliations were cataloged. The 100 most-cited articles were published from 1990 to 2012, with the majority (53) published between 2005 and 2009. The total number of citations varied from 3354 to 196, and the number of citations per year varied from 9.5 to 129.0 with a median and mean of 30.9 and 38.7, respectively. The majority of publications had a study patients sample size of 200 patients or less. The USA and Germany were the nations with the highest number of frequently cited publications. This bibliometric analysis provides insights on the most-cited articles published on the subject of cardiac CT and calcium volume, thus helping to characterize the field and guide future research. Copyright © 2016 Society of Cardiovascular Computed Tomography. Published by Elsevier Inc. All rights reserved.

  3. Scale-Independent Bibliometric Indicators

    ERIC Educational Resources Information Center

    Katz, J. Sylvan

    2005-01-01

    This article presents the author's critique of Anthony F. J. van Raan's article titled, "Measurement of Central Aspects of Scientific Research: Performance, Interdisciplinarity, Structure." van Raan makes an excellent case for using bibliometric data to measure some central aspects of scientific research and to construct indicators of…

  4. Scale-Independent Bibliometric Indicators

    ERIC Educational Resources Information Center

    Katz, J. Sylvan

    2005-01-01

    This article presents the author's critique of Anthony F. J. van Raan's article titled, "Measurement of Central Aspects of Scientific Research: Performance, Interdisciplinarity, Structure." van Raan makes an excellent case for using bibliometric data to measure some central aspects of scientific research and to construct indicators of…

  5. Scientific research on the pineal gland and melatonin: a bibliometric study for the period 1966-1994.

    PubMed

    López-Muñoz, F; Boya, J; Marín, F; Calvo, J L

    1996-04-01

    By means of teledischarge techniques from the database MEDLINE we selected those documents that contained in their title one or several of the following descriptors: pineal*, epiphys*, or melatonin*, in addition to the descriptor pineal-body in the MESH (Medical Subject Headings) section. A total of 7,617 original documents published between 1966 and 1994 were extracted that dealt with any aspect related with the pineal gland or its main secretary product, melatonin. The main bibliometric laws were applied: Price's Law on the increase in scientific literature, Bradford's Law on the dispersion of the scientific literature, and Lotka's Law on the author's productivity. Furthermore, we have analyzed the participation index (PaI) of the main countries within the global production, the productivity index of the authors (PI), and the number of authors/paper index. Our results demonstrate an exponential increase of the scientific literature on the pineal gland ("r" value = 0.983, in contrast with a "r" value = 0.966 after the linear adjustment). The number of publications on melatonin was less than those on other aspects of pineal research until 1991, when this situation was reversed. The journal with the largest number of original papers is Journal of Pineal Research (1st Bradford's zone) with 533 articles, followed by Journal of Neural Transmission (258) and Neuroendocrinology (221), which constituted the 2nd Bradford's zone. The total number of authors is 9,140, responsible for 23,524 authorships. 3.8% of the authors present a PI > or = 1 (large producers), and 64.9% a PI = 0 (occasional authors). Lotka's Law was widely fulfilled in this material since 10.3% of the authors are responsible of 50.2% of all the papers. The average number of authors per paper has changed from 2.29 in 1966 to 3.85 in 1994. The most productive country (during the interval between 1988-1994) was USA (PaI = 30.6), followed by Japan (7.15), United Kingdom (6.45), Germany (6.37), France (6

  6. Next Generation Bibliometrics and the Evolution of the ESO Telescope Bibliography

    NASA Astrophysics Data System (ADS)

    Erdmann, C.; Grothkopf, U.

    2010-10-01

    Bibliometric studies typically focus on citation and publication analysis. Due to recent advances in web technology along with greater access to web content, bibliometric research can include statistics and measures that were once difficult to obtain. The European Southern Observatory's Telescope Bibliography (ESO telbib), a content management system for refereed articles containing ESO data, provides an excellent test-bed for exploring next generation bibliometrics. Through web services provided by the NASA Astrophysics Data System (ADS) Abstract Service among others, previously unavailable information can be imported into telbib where it can be analyzed in further detail. Though some telbib features are still in their infancy, some interesting trends can already be derived.

  7. [Bibliometric study of the original articles published in the Revista Española de Salud Pública (1991-2000). I. General indicators].

    PubMed

    Pérez Andrés, Cristina; Estrada Lorenzo, José Manuel; Villar Alvarez, Fernando; Rebollo Rodríguez, M José

    2002-01-01

    For some time, the most of reports have been being disseminated by way of scientific journals, bibliometric studies therefore being fundamental to the characterization and evaluation thereof. The purpose of this study is that of characterizing the Revista Española de Salud Pública based on the original articles published therein throughout the 1991-2000 period. Original articles published in the Revista Española de Salud Pública throughout the 1991-2000 period, all inclusive. A study has been made of the following variables: number of original articles, collaboration index or number of signing authors per study, productivity index, geographical spread and main subject. Throughout the 1991-2000 period, 290 original studies (52.3%) of a total of 555 studies were published. The number of originals averaged 29 originals/year A 4.5 degree of collaboration was found to exist for this journal (number signing authors/number originals) for the period under study. The annual of originals by Autonomous Community reveals in the Autonomous Community of Madrid (20.7%), Autonomous Community of Valencia (16.4%), Andalusia (16.1%) and Catalunya (10.0%) have published studies every year throughout the ten-year period under study. The most prevalent subject of all was that related to "Communicable disease" (86 originals), Primary Health Care" (34) and "Environmental pollution" (21). Generally speaking, it apparently follows that the Revista Española de Salud Pública continues to fall within the output-related indicators of other Spanish and foreign journals and that it has also evolved in keeping with the trend proper of scientific output in the biomedical field. Although "Communicable diseases" are not the main cause of mortality, they continue being the main subject more frequently studied.

  8. Reviewers’ Ratings and Bibliometric Indicators: Hand in Hand When Assessing Over Research Proposals?

    PubMed Central

    Cabezas-Clavijo, Álvaro; Robinson-García, Nicolás; Escabias, Manuel; Jiménez-Contreras, Evaristo

    2013-01-01

    Background The peer review system has been traditionally challenged due to its many limitations especially for allocating funding. Bibliometric indicators may well present themselves as a complement. Objective We analyze the relationship between peers’ ratings and bibliometric indicators for Spanish researchers in the 2007 National R&D Plan for 23 research fields. Methods and Materials We analyze peers’ ratings for 2333 applications. We also gathered principal investigators’ research output and impact and studied the differences between accepted and rejected applications. We used the Web of Science database and focused on the 2002-2006 period. First, we analyzed the distribution of granted and rejected proposals considering a given set of bibliometric indicators to test if there are significant differences. Then, we applied a multiple logistic regression analysis to determine if bibliometric indicators can explain by themselves the concession of grant proposals. Results 63.4% of the applications were funded. Bibliometric indicators for accepted proposals showed a better previous performance than for those rejected; however the correlation between peer review and bibliometric indicators is very heterogeneous among most areas. The logistic regression analysis showed that the main bibliometric indicators that explain the granting of research proposals in most cases are the output (number of published articles) and the number of papers published in journals that belong to the first quartile ranking of the Journal Citations Report. Discussion Bibliometric indicators predict the concession of grant proposals at least as well as peer ratings. Social Sciences and Education are the only areas where no relation was found, although this may be due to the limitations of the Web of Science’s coverage. These findings encourage the use of bibliometric indicators as a complement to peer review in most of the analyzed areas. PMID:23840840

  9. Reviewers' ratings and bibliometric indicators: hand in hand when assessing over research proposals?

    PubMed

    Cabezas-Clavijo, Alvaro; Robinson-García, Nicolás; Escabias, Manuel; Jiménez-Contreras, Evaristo

    2013-01-01

    The peer review system has been traditionally challenged due to its many limitations especially for allocating funding. Bibliometric indicators may well present themselves as a complement. We analyze the relationship between peers' ratings and bibliometric indicators for Spanish researchers in the 2007 National R&D Plan for 23 research fields. We analyze peers' ratings for 2333 applications. We also gathered principal investigators' research output and impact and studied the differences between accepted and rejected applications. We used the Web of Science database and focused on the 2002-2006 period. First, we analyzed the distribution of granted and rejected proposals considering a given set of bibliometric indicators to test if there are significant differences. Then, we applied a multiple logistic regression analysis to determine if bibliometric indicators can explain by themselves the concession of grant proposals. 63.4% of the applications were funded. Bibliometric indicators for accepted proposals showed a better previous performance than for those rejected; however the correlation between peer review and bibliometric indicators is very heterogeneous among most areas. The logistic regression analysis showed that the main bibliometric indicators that explain the granting of research proposals in most cases are the output (number of published articles) and the number of papers published in journals that belong to the first quartile ranking of the Journal Citations Report. Bibliometric indicators predict the concession of grant proposals at least as well as peer ratings. Social Sciences and Education are the only areas where no relation was found, although this may be due to the limitations of the Web of Science's coverage. These findings encourage the use of bibliometric indicators as a complement to peer review in most of the analyzed areas.

  10. Bibliometric Indicators of University Research Performance in Flanders.

    ERIC Educational Resources Information Center

    Van den Berghe, Herman; Houben, Josee A.; de Bruin, Renger E.; Moed, Henk F.; Kint, Andre; Spruyt, Eric H. J.; Luwel, Marc

    1998-01-01

    Bibliometric studies were conducted on research performance at three Flemish universities: University of Ghent, Catholic University of Leuven, and University of Antwerp. This article outlines the methodology, presents the outcomes for the faculties of medicine, science, and pharmaceutical science; and focuses on the reactions of department…

  11. CALL: Past, Present and Future--A Bibliometric Approach

    ERIC Educational Resources Information Center

    Jung, Udo O. H.

    2005-01-01

    A bibliometric approach is used not only to sketch out the development of CALL during the last 25 years, but also to assess the contribution of educational technology to 21st century foreign-language teaching and learning. This study is based on the six instalments of the author's International (and multilingual) Bibliography of Computer Assisted…

  12. Cell Phones: A Bibliometric Analysis Related to Business Students

    ERIC Educational Resources Information Center

    Piotrowski, Chris

    2014-01-01

    Recent reviews of the literature indicate that the scope of research on cell or mobile phones covers a vast typology (Piotrowski & Kass, 2013). The majority of this research is concentrated in the technology, education, and social sciences fields. However, there is a dearth of bibliometric studies on cell phones related to business. To that…

  13. Cell Phones: A Bibliometric Analysis Related to Business Students

    ERIC Educational Resources Information Center

    Piotrowski, Chris

    2014-01-01

    Recent reviews of the literature indicate that the scope of research on cell or mobile phones covers a vast typology (Piotrowski & Kass, 2013). The majority of this research is concentrated in the technology, education, and social sciences fields. However, there is a dearth of bibliometric studies on cell phones related to business. To that…

  14. The Poisson-Lognormal Model for Bibliometric/Scientometric Distributions.

    ERIC Educational Resources Information Center

    Stewart, John A.

    1994-01-01

    Illustrates that the Poisson-lognormal model provides good fits to a diverse set of distributions commonly studied in bibliometrics and scientometrics. Topics discussed include applications to the empirical data sets related to the laws of Lotka, Bradford, and Zipf; causal processes that could generate lognormal distributions; and implications for…

  15. Analysis of bibliometric indicators to determine citation bias

    USDA-ARS?s Scientific Manuscript database

    Publications from the 1995 to 2004 period (and cited throughout July 2013) were analyzed to determine if the plant species used in research studies influenced the number of citations that papers received. Bibliometric data of papers from 108 plant species were obtained for the research fields of Gen...

  16. Bibliometric indexes, databases and impact factors in cardiology.

    PubMed

    Bienert, Igor R C; Oliveira, Rogério Carvalho de; Andrade, Pedro Beraldo de; Caramori, Carlos Antonio

    2015-01-01

    Bibliometry is a quantitative statistical technique to measure levels of production and dissemination of knowledge, as well as a useful tool to track the development of an scientific area. The valuation of production required for recognition of researchers and magazines is accomplished through tools called bibliometric indexes, divided into quality indicators and scientific impact. Initially developed for monographs of statistical measures especially in libraries, today bibliometrics is mainly used to evaluate productivity of authors and citation repercussion. However, these tools have limitations and sometimes provoke controversies about indiscriminate application, leading to the development of newer indexes. It is important to know the most common search indexes and use it properly even acknowledging its limitations as it has a direct impact in their daily practice, reputation and funds achievement.

  17. A Bibliometric Analysis on Cancer Population Science with Topic Modeling.

    PubMed

    Li, Ding-Cheng; Rastegar-Mojarad, Majid; Okamoto, Janet; Liu, Hongfang; Leichow, Scott

    2015-01-01

    Bibliometric analysis is a research method used in library and information science to evaluate research performance. It applies quantitative and statistical analyses to describe patterns observed in a set of publications and can help identify previous, current, and future research trends or focus. To better guide our institutional strategic plan in cancer population science, we conducted bibliometric analysis on publications of investigators currently funded by either Division of Cancer Preventions (DCP) or Division of Cancer Control and Population Science (DCCPS) at National Cancer Institute. We applied two topic modeling techniques: author topic modeling (AT) and dynamic topic modeling (DTM). Our initial results show that AT can address reasonably the issues related to investigators' research interests, research topic distributions and popularities. In compensation, DTM can address the evolving trend of each topic by displaying the proportion changes of key words, which is consistent with the changes of MeSH headings.

  18. A Bibliometric Analysis on Cancer Population Science with Topic Modeling

    PubMed Central

    Li, Ding-Cheng; Rastegar-Mojarad, Majid; Okamoto, Janet; Liu, Hongfang; Leichow, Scott

    2015-01-01

    Bibliometric analysis is a research method used in library and information science to evaluate research performance. It applies quantitative and statistical analyses to describe patterns observed in a set of publications and can help identify previous, current, and future research trends or focus. To better guide our institutional strategic plan in cancer population science, we conducted bibliometric analysis on publications of investigators currently funded by either Division of Cancer Preventions (DCP) or Division of Cancer Control and Population Science (DCCPS) at National Cancer Institute. We applied two topic modeling techniques: author topic modeling (AT) and dynamic topic modeling (DTM). Our initial results show that AT can address reasonably the issues related to investigators’ research interests, research topic distributions and popularities. In compensation, DTM can address the evolving trend of each topic by displaying the proportion changes of key words, which is consistent with the changes of MeSH headings. PMID:26306249

  19. Quantitative genetic studies of antisocial behaviour.

    PubMed

    Viding, Essi; Larsson, Henrik; Jones, Alice P

    2008-08-12

    This paper will broadly review the currently available twin and adoption data on antisocial behaviour (AB). It is argued that quantitative genetic research can make a significant contribution to further the understanding of how AB develops. Genetically informative study designs are particularly useful for investigating several important questions such as whether: the heritability estimates vary as a function of assessment method or gender; the relative importance of genetic and environmental influences varies for different types of AB; the environmental risk factors are truly environmental; and genetic vulnerability influences susceptibility to environmental risk. While the current data are not yet directly translatable for prevention and treatment programmes, quantitative genetic research has concrete translational potential. Quantitative genetic research can supplement neuroscience research in informing about different subtypes of AB, such as AB coupled with callous-unemotional traits. Quantitative genetic research is also important in advancing the understanding of the mechanisms by which environmental risk operates.

  20. [Anales Españoles de Pediatría 2001. Bibliometric indicators of scientific quality].

    PubMed

    González de Dios, J

    2002-08-01

    BACKGROUND. One important objective of Anales Españoles de Pediatría (An Esp Pediatr) is to be included in Journal Citation Reports-Science Citation Index and the main step to achieve this is to increase the scientific quality of this Spanish journal. Bibliometric indicators are important tools used to determine the quality of scientific publications. A bibliometric study of all the original articles published in An Esp Pediatr in 2001 (n 76) was performed; bibliometric indicators were classified into quantitative and qualitative (statistical analyses and level of scientific evidence). The results were compared with the original articles published in the journal from 1994 to June 2000 (n 733) and with the original articles published in Pediatrics in 2001 (n 276). The differences found in An Esp Pediatr between the two study periods were the following in 2001: greater collaboration between epidemiologists and/or biostatisticians in the authorship of articles (19.7 %), increased complexity of statistical analyses (statistical accessibility > 7 in 25 %) and greater use of evidence-based methodological concepts (19.7 %). However, no improvement was found in the scientific evidence (evidence was good in only 1.4 % and average in 25.7 %). Other aspects of interest were a lower number of original articles (due to an increase in other types of articles, such as Letters to the Editor or Special Articles) and a greater percentage of articles on evidence-based medicine or articles using its methodology. The differences in bibliometric indicators of quality found between An Esp Pediatr and Pediatrics continued to be considerable: statistical accessibility, evidence-based methodological concepts and scientific evidence (for example, good evidence was 22 times more frequent in Pediatrics). The scientific quality of An Esp Pediatr improved in 2001 compared with that of previous years, but the differences found between this journal and the gold standard of Pediatrics are still

  1. THE EVOLUTION OF THE JOURNAL OF APPLIED ORAL SCIENCE: A BIBLIOMETRIC ANALYSIS

    PubMed Central

    Ferraz, Valéria Cristina Trindade; Amadei, José Roberto Plácido; Santos, Carlos Ferreira

    2008-01-01

    The purpose of this study was to make a brief diagnosis of the evolution of the Journal of Applied Oral Science (JAOS) between 2005 and 2007, by reviewing quantitative and qualitative aspects of the articles published in the JAOS within this period. All articles published in the JAOS in the time span established for this survey were analyzed retrospectively and a discussion was undertaken on the data referring to the main bibliometric indexes of production, authorship, bibliographic sources of the published articles, and the most frequently cited scientific journals in the main dental research fields. A total of 247 papers authored and coauthored by 1,139 contributors were reviewed, most of them being original research articles. The number of authors per article was 4.61 on the average. Regarding the geographic distribution, the authors represented almost all of the Brazilian States. Most published articles belonged to the following dental research fields: Endodontics, Restorative Dentistry, Dental Materials and Prosthodontics. The ranking of the most frequently cited scientific journals included the most reputable publications in these dental research fields. In conclusion, between 2005 and 2007, the JAOS either maintained or improved considerably its bibliometric indexes. The analysis of the data retrieved in this study allowed evaluating the journal's current management strategies, and identifying important issues that will help outlining the future directions for the internationalization of this journal. PMID:19082402

  2. The evolution of the Journal of Applied Oral Science: a bibliometric analysis.

    PubMed

    Ferraz, Valéria Cristina Trindade; Amadei, José Roberto Plácido; Santos, Carlos Ferreira

    2008-01-01

    The purpose of this study was to make a brief diagnosis of the evolution of the Journal of Applied Oral Science (JAOS) between 2005 and 2007, by reviewing quantitative and qualitative aspects of the articles published in the JAOS within this period. All articles published in the JAOS in the time span established for this survey were analyzed retrospectively and a discussion was undertaken on the data referring to the main bibliometric indexes of production, authorship, bibliographic sources of the published articles, and the most frequently cited scientific journals in the main dental research fields. A total of 247 papers authored and co-authored by 1,139 contributors were reviewed, most of them being original research articles. The number of authors per article was 4.61 on the average. Regarding the geographic distribution, the authors represented almost all of the Brazilian States. Most published articles belonged to the following dental research fields: Endodontics, Restorative Dentistry, Dental Materials and Prosthodontics. The ranking of the most frequently cited scientific journals included the most reputable publications in these dental research fields. In conclusion, between 2005 and 2007, the JAOS either maintained or improved considerably its bibliometric indexes. The analysis of the data retrieved in this study allowed evaluating the journal's current management strategies, and identifying important issues that will help outlining the future directions for the internationalization of this journal.

  3. Global Regulatory T-Cell Research from 2000 to 2015: A Bibliometric Analysis

    PubMed Central

    Zongyi, Yin; Dongying, Chen

    2016-01-01

    We aimed to analyze the global scientific output of regulatory T-cell (Treg) research and built a model to qualitatively and quantitatively evaluate publications from 2000 to 2015. Data were obtained from the Web of Science Core Collection (WoSCC) of Thomson Reuters on January 1, 2016. The bibliometric method and Citespace III were used to analyze authors, journals, publication outputs, institutions, countries, research areas, research hotspots, and trends. In total, we identified 35,741 publications on Treg research from 2000 to 2015, and observed that the annual publication rate increased with time. The Journal of Immunology published the highest number of articles, the leading country was the USA, and the leading institute was Harvard University. Sakaguchi, Hori, Fontenot, and Wang were the top authors in Treg research. Immunology accounted for the highest number of publications, followed by oncology, experimental medicine, cell biology, and hematology. Keyword analysis indicated that autoimmunity, inflammation, cytokine, gene expression, foxp3, and immunotherapy were the research hotspots, whereas autoimmune inflammation, gene therapy, granzyme B, RORγt, and th17 were the frontiers of Treg research. This bibliometric analysis revealed that Treg-related studies are still research hotspots, and that Treg-related clinical therapies are the research frontiers; however, further study and collaborations are needed worldwide. Overall, our findings provide valuable information for the editors of immunology journals to identify new perspectives and shape future research directions. PMID:27611317

  4. Subject, function, and trend in medical ethics research: a comparative study of Chinese and non-Chinese literature using bibliometrics.

    PubMed

    Jiang, Lanhui; Shen, Jiantong; Li, Youping; Deng, Shaolin; Wu, Taixiang; Chen, Baoqing; Xie, Zhiyi; Qin, Chaoyi; Yu, Zhiyuan; Qin, Chuan; Huang, Jin; Liu, Xuemei; Li, Yan; Jiang, Jie

    2012-05-01

    To perform a comparative quantitative and qualitative analysis of Chinese and non-Chinese medical ethics literature using systematic research and literature analysis in order to discern research trends in the area and provide baseline data as a reference for relevant decision making and further study. We retrieved articles using MeSH terms and keywords related to medical ethics in PubMed and CNKI, and then constructed a set of charts by applying word co-occurrence, The Pathfinder Networks algorithms, an included subject chart, a research field relationship chart, and strategy coordination charts. The total of number of papers retrieved from PubMed was six times that retrieved from CNKI. Outside China, medical ethics has been studied in eight fully shaped subject fields, including morals, ethical review, physician-patient relationships, clinical trials, euthanasia, ethics education, clinical ethics, and health policy. In contrast, medical ethics research in China is still confined to five subject fields: morals, physician-patient relations, medical ethics education, ethical review, and medical research. Medical ethics research outside China emphasizes the application of medical ethics to solve emerging problems in clinical and medical research. It is mainly centered on morals, ethical review, and physician-patient relations. By comparison, medical ethics research in China places greater emphasis on morals and medical education. In order to narrow this gap between China and other countries, we should broaden the research scope of medical ethics and add more applied research, such as ethical review and medical education. © 2012 Blackwell Publishing Asia Pty Ltd and Chinese Cochrane Center, West China Hospital of Sichuan University.

  5. Nursing informatics competencies: bibliometric analysis.

    PubMed

    Kokol, Peter; Blažun, Helena; Vošner, Janez; Saranto, Kaija

    2014-01-01

    Information and communication technology is developing rapidly and it is incorporated in many health care processes, but in spite of that fact we can still notice that nursing informatics competencies had received limited attention in basic nursing education curricula in Europe and especially in Eastern European countries. The purpose of the present paper is to present the results of a bibliometric analysis of the nursing informatics competencies scientific literature production. We applied the bibliometrics analysis to the corpus of 332 papers found in SCOPUS, related to nursing informatics competencies. The results showed that there is a positive trend in the number of published papers per year, indicating the increased research interest in nursing informatics competencies. Despite the fact that the first paper was published in Denmark, the most prolific country regarding the research in nursing informatics competencies is United States as are their institutions and authors.

  6. Bibliometrics: The best available information?

    PubMed

    Klein, Waldo C; Bloom, Martin

    2005-01-01

    This commentary raises significant cautions related to inherent shortcomings in the use of bibliographic analytic technology, and in particular its use in substantive decision making around promotion and tenure. Questions are raised concerning the continued use of scholarly energy for bibliometric analysis of subtly different settings. The recommendation is offered that future efforts in bibliometrics must target methods to reduce methodological shortcomings. These include clarifying the metric used to count sole/multiple authorship, and to evaluate the"merit" of manuscripts as well as journals in which they appear. Finally, the fundamental meaning of the information produced in these analyses (i.e., the validity of the measure) must be clearly presented in order for it to be credibly used.

  7. Empirical Laws, Theory Construction and Bibliometrics.

    ERIC Educational Resources Information Center

    O'Connor, Daniel O.; Voos, Henry

    1981-01-01

    Examines the properties of bibliometric distributions (application of mathematics and statistical methods to books and other written communications) in a nontechnical manner, covering similarities of the Lotka, Bradford, and Zipf distributions, the relationship between empirical laws and theories, and bibliometric concepts and theory construction.…

  8. Critical Quantitative Study of Immigrant Students

    ERIC Educational Resources Information Center

    Conway, Katherine M.

    2014-01-01

    The author discusses the importance of critical quantitative research for studies of immigrant students, a large and growing group, whose higher education experience is crucial to the future of the United States. The author outlines some of the distinctions to be made among immigrant students and recommends areas of future inquiry.

  9. Critical Quantitative Study of Immigrant Students

    ERIC Educational Resources Information Center

    Conway, Katherine M.

    2014-01-01

    The author discusses the importance of critical quantitative research for studies of immigrant students, a large and growing group, whose higher education experience is crucial to the future of the United States. The author outlines some of the distinctions to be made among immigrant students and recommends areas of future inquiry.

  10. Bibliometric indicators: quality measurements of scientific publication.

    PubMed

    Durieux, Valérie; Gevenois, Pierre Alain

    2010-05-01

    Bibliometrics is a set of mathematical and statistical methods used to analyze and measure the quantity and quality of books, articles, and other forms of publications. There are three types of bibliometric indicators: quantity indicators, which measure the productivity of a particular researcher; quality indicators, which measure the quality (or "performance") of a researcher's output; and structural indicators, which measure connections between publications, authors, and areas of research. Bibliometric indicators are especially important for researchers and organizations, as these measurements are often used in funding decisions, appointments, and promotions of researchers. As more and more scientific discoveries occur and published research results are read and then quoted by other researchers, bibliometric indicators are becoming increasingly important. This article provides an overview of the currently used bibliometric indicators and summarizes the critical elements and characteristics one should be aware of when evaluating the quantity and quality of scientific output.

  11. Ascertaining Activities in a Subject Area Through Bibliometric Analysis; Application to "Library Literature"

    ERIC Educational Resources Information Center

    Saracevic, Tefko; Perk, Lawrence J.

    1973-01-01

    A combination of quantitative and qualitative techniques were used to analize the journal articles indexed in one volume of Library Literature.'' This approach, merging bibliometrics and classification, yielded results in such areas as dispersion of articles among journals, frequency of article type and types of subjects covered. (16 references)…

  12. Ascertaining Activities in a Subject Area Through Bibliometric Analysis; Application to "Library Literature"

    ERIC Educational Resources Information Center

    Saracevic, Tefko; Perk, Lawrence J.

    1973-01-01

    A combination of quantitative and qualitative techniques were used to analize the journal articles indexed in one volume of Library Literature.'' This approach, merging bibliometrics and classification, yielded results in such areas as dispersion of articles among journals, frequency of article type and types of subjects covered. (16 references)…

  13. Rain research with disdrometers: a bibliometric review

    NASA Astrophysics Data System (ADS)

    Fernandez-Raga, M.; Palencia, C.; Tomas, C.; Calvo, A. I.; Castro, A.; Fraile, R.

    2011-09-01

    This study analyses the research on disdrometers based on published studies. To do so, a wide data base of bibliographic references has been used: the Web of Science (published by Thomson Reuters). The search was carried out for all of the articles whose "TOPIC" was disdrometer. The more than 300 articles found were analysed according to various criteria: countries with research using disdrometers; publication dates; evolution of the number of articles; concepts studied and research lines followed in each article; and finally, a bibliometric analysis of the more than 60 journals where these articles have been published. Since 1963, there has been an increase in the number of articles published on disdrometers, which in the last 20 yr has been more than ten times higher than the increase in the number of articles on meteorology.

  14. [Bibliometric study of original articles in the Revista Española de Salud Pública (1991-2000). Part II: authors' productivity, their institutions and geographical areas].

    PubMed

    Estrada Lorenzo, José Manuel; Villar Alvarez, Fernando; Pérez Andrés, Cristina; Rebollo Rodríguez, M José

    2003-01-01

    When characterizing a scientific journal from the bibliometric standpoint, it is of importance to know how many authors were involved in the studies published as well as the geographical areas where these authors are located and the type of institutions by which they are employed. The aim of this article is that of analyzing the geographical spread of these authors and the institutions by which they are employed, as well as its evolution as regards the original articles published in the Revista Española de Salud Pública throughout the 1991-2000 period. Of the original articles published in the Revista Española de Salud Pública throughout the studied ten-year period, a calculation has been made as to the total number of authors, the number of occasional authors (authors having published solely one article), transitivity index, the ratio between the number of male and female authors, the productivity of the authors and their institutions and the spread of authors and the institutions by which they are employed by Autonomous Communities. Of the original articles published in the Revista Española de Salud Pública throughout the 1991-2000 period, a total of 1,052 different authors were involved, 1,000 of whom were Spanish and 52 foreigners. The ratio of male authors to female authors for the period in question was 1.29. The Autonomous Communities from which the largest number of authors came were Community of Madrid (16.3%), Andalusia (13.4%) and the Community of Valencia (12.5%). The institutions by which the authors are employed are located most often in Community of Madrid (16.5%), in Community of Valencia (11.3%) and Andalusia and Catalonia (10.5%). A total of 37.6% of the authors work at centers devoted to health care, followed by authors who work at Universities (26.3%). On calculating the spread of the type of institution by Autonomous Communities, in the Community of Madrid and in the Community of Valencia and Andalusia, the most frequent institution is

  15. Characteristics and popular topics of latest researches into the effects of air particulate matter on cardiovascular system by bibliometric analysis.

    PubMed

    Jia, Xiaofeng; Guo, Xinbiao; Li, Haicun; An, Xinying; Zhao, Yingguang

    2013-03-01

    In recent years, many epidemiological and toxicological studies have investigated the adverse effects of air particulate matter (PM) on the cardiovascular system. However, it is difficult for the researchers to have a timely and effective overall command of the latest characteristics and popular topics in such a wide field. Different from the previous reviews, in which the research characteristics and trends are empirically concluded by experts, we try to have a comprehensive evaluation of the above topics for the first time by bibliometric analysis, a quantitative tool in information exploration. This study aims to introduce the bibliometric method into the field of PM and cardiovascular system. The articles were selected by searching PubMed/MEDLINE (from 2007 to 2012) using Medical Subject Headings (MeSH) terms "particulate matter" and "cardiovascular system". A total of 935 eligible articles and 1895 MeSH terms were retrieved and processed by the software Thomson Data Analyzer (TDA). The bibliographic information and the MeSH terms of these articles were classified and analyzed to summarize the research characteristics. The top 200 high-frequency MeSH terms (the cumulative frequency percentage was 74.2%) were clustered for popular-topic conclusion. We summarized the characteristics of published articles, of researcher collaborations and of the contents. Ten clusters of MeSH terms are presented. Six popular topics are concluded and elaborated for reference. Our study presents an overview of the characteristics and popular topics in the field of PM and cardiovascular system in the past five years by bibliometric tools, which may provide a new perspective for future researchers.

  16. Origins of Life Research: a Bibliometric Approach.

    PubMed

    Aydinoglu, Arsev Umur; Taşkın, Zehra

    2017-07-13

    This study explores the collaborative nature and interdisciplinarity of the origin(s) of life (OoL) research community. Although OoL research is one of the oldest topics in philosophy, religion, and science; to date there has been no review of the field utilizing bibliometric measures. A dataset of 5647 publications that are tagged as OoL, astrobiology, exobiology, and prebiotic chemistry is analyzed. The most prolific authors (Raulin, Ehrenfreund, McKay, Cleaves, Cockell, Lazcano, etc.), most cited scholars and their articles (Miller 1953, Gilbert 1986, Chyba & Sagan 1992, Wȁchtershȁuser 1988, etc.), and popular journals (Origins of Life and Evolution of Biospheres and Astrobiology) for OoL research are identified. Moreover, interdisciplinary research conducted through research networks, institutions (NASA, Caltech, University of Arizona, University of Washington, CNRS, etc.), and keywords & concepts (astrobiology, life, Mars, amino acid, prebiotic chemistry, evolution, RNA) are explored.

  17. Origins of Life Research: a Bibliometric Approach

    NASA Astrophysics Data System (ADS)

    Aydinoglu, Arsev Umur; Taşkın, Zehra

    2017-07-01

    This study explores the collaborative nature and interdisciplinarity of the origin(s) of life (OoL) research community. Although OoL research is one of the oldest topics in philosophy, religion, and science; to date there has been no review of the field utilizing bibliometric measures. A dataset of 5647 publications that are tagged as OoL, astrobiology, exobiology, and prebiotic chemistry is analyzed. The most prolific authors (Raulin, Ehrenfreund, McKay, Cleaves, Cockell, Lazcano, etc.), most cited scholars and their articles (Miller 1953, Gilbert 1986, Chyba & Sagan 1992, Wȁchtershȁuser 1988, etc.), and popular journals (Origins of Life and Evolution of Biospheres and Astrobiology) for OoL research are identified. Moreover, interdisciplinary research conducted through research networks, institutions (NASA, Caltech, University of Arizona, University of Washington, CNRS, etc.), and keywords & concepts (astrobiology, life, Mars, amino acid, prebiotic chemistry, evolution, RNA) are explored.

  18. Is bilingualism losing its advantage? A bibliometric approach.

    PubMed

    Sanchez-Azanza, Victor A; López-Penadés, Raúl; Buil-Legaz, Lucía; Aguilar-Mediavilla, Eva; Adrover-Roig, Daniel

    2017-01-01

    This study uses several bibliometric indices to explore the temporal course of publication trends regarding the bilingual advantage in executive control over a ten-year window. These indices include the number of published papers, numbers of citations, and the journal impact factor. According to the information available in their abstracts, studies were classified into one of four categories: supporting, ambiguous towards, not mentioning, or challenging the bilingual advantage. Results show that the number of papers challenging the bilingual advantage increased notably in 2014 and 2015. Both the average impact factor and the accumulated citations as of June 2016 were equivalent between categories. However, of the studies published in 2014, those that challenge the bilingual advantage accumulated more citations in June 2016 than those supporting it. Our findings offer evidence-based bibliometric information about the current state of the literature and suggest a change in publication trends regarding the literature on the bilingual advantage.

  19. [New bibliometric indicators for the scientific literature: an evolving panorama].

    PubMed

    La Torre, G; Sciarra, I; Chiappetta, M; Monteduro, A

    2017-01-01

    Bibliometrics is a science which evaluates the impact of the scientific work of a journal or of an author, using mathematical and statistical tools. Impact Factor (IF) is the first bibliometric parameter created, and after it many others have been progressively conceived in order to go beyond its limits. Currently bibliometric indexes are used for academic purposes, among them to evaluate the eligibility of a researcher to compete for the National Scientific Qualification, in order to access to competitive exams to become professor. Aim of this study is to identify the most relevant bibliometric indexes and to summarized their characteristics. A revision of bibliometric indexes as been conducted, starting from the classic ones and completing with the most recent ones. The two most used bibliometric indexes are the IF, which measures the scientific impact of a periodical and bases on Web of Science citation database, and the h-index, which measures the impact of the scientific work of a researcher, basing on Scopus database. Besides them other indexes have been created more recently, such as the SCImago Journal Rank Indicator (SJR), the Source Normalised Impact per Paper (SNIP) and the CiteScore index. They are all based on Scopus database and evaluate, in different ways, the citational impact of a periodic. The i10-index instead is provided from Google Scholar database and allows to evaluate the impact of the scientific production of a researcher. Recently two softwares have been introduced: the first one, Publish or Perish, allows to evaluate the scientific work of a researcher, through the assessment of many indexes; the second one, Altmetric, measure the use in the Web of the academic papers, instead of measuring citations, by means of alternative metrics respect to the traditional ones. Each analized index shows advantages but also criticalities. Therefore the combined use of more than one indexes, citational and not, should be preferred, in order to correctly

  20. Bibliometric analysis of lung transplantation research articles.

    PubMed

    Eshraghi, M; Habibi, G; Rahim, M B; Mirkazemi, R; Ghaemi, M; Omidimorad, A; Alavi, A A; Banazadeh, M

    2011-03-01

    In the last 30 years lung transplantation has proven to be a lifesaving therapeutic option for patients with end-stage lung disease. The objective of this study was to perform a bibliometric analysis of lung transplantation research articles. A bibliometric evaluation of the evolution of scientific production in the field of lung transplantations between 1989 and 2009 was conducted using the ISI Web of Science. The search terms selected were "lung transplant" OR "pulmonary transplant". Specific features including year of publication, language, geographical distribution, first author, main journal publishing these articles, journals publishing highly cited articles, and institutional affiliation were analyzed. The citation characteristics of articles were additionally analyzed. A total of 6409 (58.0 %) research articles were found. The time trend of the number of articles showed an increase of more than 6.81 between 1989 and 2009. North America contributed 50.4 % and Europe contributed 46.0 % of published articles. The greatest number of contributions came from the USA (43.6 %), followed by England (9.1 %) and Germany (8.6 %). There were 104 522 citations of these articles by 25 July 2010. The average citation per article was 16.31. The New England Journal of Medicine ranked first with regard to the number of articles and the number of highly cited articles. G. A. Patterson, Washington University, and the US National Institutes of Health (NIH) were the top author, institution and funding agency, respectively. The number of publications and the scientific interest in lung transplantation has increased rapidly in recent years. Citations of articles published in the field of lung transplantation are increasing and the numbers of uncited articles are fewer compared to the average citations of articles and uncited articles in the field of medicine. © Georg Thieme Verlag KG Stuttgart · New York.

  1. The challenge of assessing the impact of science beyond bibliometrics.

    PubMed

    Barreto, Mauricio L

    2013-08-01

    It is hoped that the knowledge produced by scientific research turns into concrete benefits (material or non-material). Bibliometrics, with its various indexes, became the reference of scientific evaluation as an "objective" measure of scientific impact. In Brazil, the evaluation system focused on CAPES has been of great importance for the development of postgraduate studies and research; however changes are necessary, among others, to its bibliometric approach. If we consider the area of health, the challenge of the Unified Health System (SUS) implies the search for scientifically sound alternatives, regarding questions ranging from diagnosis, cure and prevention of a variety of problems, to the organization of a macro-structure capable of giving broad and equal access to the resources required for improving the health of the population. The solutions require expertise and creativity on the part of the researchers and the expected products must include, but are not limited to scientific publications.

  2. Scientific publication productivity of Libyan medical schools: a bibliometric study of papers listed in PubMed, 1988-2007.

    PubMed

    Benamer, H T S; Bredan, A; Bakoush, O

    2009-08-01

    Scientific publication is a vital mission of medical schools and it is important to periodically document how well schools fulfil this mission. This study aimed to analyse the publication record of Libyan medical schools in international journals indexed in PubMed between 1988 and 2007. Medline was searched using PubMed for publications affiliated to Libya during 1988-2007. Out of 417 papers related to Libya, 348 (84%) are affiliated to the medical schools and related hospitals. More than 60% of the 348 papers are affiliated to Al-Arab Medical University, Benghazi, while Al-Fateh Medical University, Tripoli, contributed 103 papers (30%). The rest of the papers (n=25, 7%) were published by medical schools in other parts of the country. The publication rate declined by 3% annually between 1988 and 2007. The decline was mainly due to a decrease in the publication rate by Al-Arab Medical University, Benghazi. Overall, nine departments produced 10 or more papers each. Out of about 1675 staff members, there are only 148 first authors and 207 last authors. The estimated annual publication rate is 0.7 papers per 100 academic staff members. This study reveals that published scholarship of the Libyan medical schools is extremely low, that the publication rate has declined, and that most academic staff have no publications listed in PubMed. This issue needs urgent attention.

  3. How have the Eastern European countries of the former Warsaw Pact developed since 1990? A bibliometric study.

    PubMed

    Kozak, Marcin; Bornmann, Lutz; Leydesdorff, Loet

    Did the demise of the Soviet Union in 1991 influence the scientific performance of the researchers in Eastern European countries? Did this historical event affect international collaboration by researchers from the Eastern European countries with those of Western countries? Did it also change international collaboration among researchers from the Eastern European countries? Trying to answer these questions, this study aims to shed light on international collaboration by researchers from the Eastern European countries (Russia, Ukraine, Belarus, Moldova, Bulgaria, the Czech Republic, Hungary, Poland, Romania, and Slovakia). The number of publications and normalized citation impact values are compared for these countries based on InCites (Thomson Reuters), from 1981 up to 2011. The international collaboration by researchers affiliated to institutions in Eastern European countries at the time points of 1990, 2000 and 2011 was studied with the help of Pajek and VOSviewer software, based on data from the Science Citation Index (Thomson Reuters). Our results show that the breakdown of the communist regime did not lead, on average, to a huge improvement in the publication performance of the Eastern European countries and that the increase in international co-authorship relations by the researchers affiliated to institutions in these countries was smaller than expected. Most of the Eastern European countries are still subject to changes and are still awaiting their boost in scientific development.

  4. [Bibliometric study of the journal Actas Dermo-Sifiliográficas(1984-2003) II. Analysis of bibliographical references].

    PubMed

    Miralles, Julia; Ramos, José M; Ballester, Rosa; Belinchón, Isabel; Sevila, Amparo; Moragón, Manuel

    2005-11-01

    To quantify the number of references for each of the articles published in the regular issues of the journal Actas Dermo-Sifiliográficas (AD) between 1984 and 2003, and to calculate the average number of references for each of these years. To study the consumption of information by the authors of documents published in AD through the analysis of all of the bibliographical references listed in the articles published in 1984, 1993 and 2003. The number of references for each of the scientific articles published in the regular issues of the journal Actas Dermo-Sifiliográficas between 1984 and 2003 was reviewed manually. For the years 1984, 1993 and 2003, the type of document, language, country of origin and age of the references were analyzed. The 2,604 articles published in the journal AD between 1984 and 2003 provided 56,144 references. The average number of references per article for the entire period was 21.56 +/- 21.2. The type of document with the most references was the review (67.06 +/- 59.9), followed by original works (24.76 +/- 19) and clinical cases (17.95 +/- 9.7). The primary type of document for references in the three years studied was the review article, which went from 84.8 % in 1984 to 95.4 % in 2003. References to books, on the other hand, dropped from 10.6 % in the first year to 3.3 % in the last one (p < 0.001). The United States was the country of origin of a large part of the references reflected in the three years studied (55.4 %). Following at a great distance were the United Kingdom (15.7 %) and Spain (9 %). English was the language in which most of the references were written in the three years studied, increasing from 72.9 % in 1984 to 87.5 % in 2003. Spanish was the second most used language in the references (9.1 %); contrary to what was expected, its use decreased over the three years. The main journals referenced by the authors published in AD were the American publications Archives of Dermatology (12.3 %) and Journal of the American

  5. TECHNOLOGICAL INNOVATION IN NEUROSURGERY: A QUANTITATIVE STUDY

    PubMed Central

    Marcus, Hani J; Hughes-Hallett, Archie; Kwasnicki, Richard M; Darzi, Ara; Yang, Guang-Zhong; Nandi, Dipankar

    2015-01-01

    Object Technological innovation within healthcare may be defined as the introduction of a new technology that initiates a change in clinical practice. Neurosurgery is a particularly technologically intensive surgical discipline, and new technologies have preceded many of the major advances in operative neurosurgical technique. The aim of the present study was to quantitatively evaluate technological innovation in neurosurgery using patents and peer-reviewed publications as metrics of technology development and clinical translation respectively. Methods A patent database was searched between 1960 and 2010 using the search terms “neurosurgeon” OR “neurosurgical” OR “neurosurgery”. The top 50 performing patent codes were then grouped into technology clusters. Patent and publication growth curves were then generated for these technology clusters. A top performing technology cluster was then selected as an exemplar for more detailed analysis of individual patents. Results In all, 11,672 patents and 208,203 publications relating to neurosurgery were identified. The top performing technology clusters over the 50 years were: image guidance devices, clinical neurophysiology devices, neuromodulation devices, operating microscopes and endoscopes. Image guidance and neuromodulation devices demonstrated a highly correlated rapid rise in patents and publications, suggesting they are areas of technology expansion. In-depth analysis of neuromodulation patents revealed that the majority of high performing patents were related to Deep Brain Stimulation (DBS). Conclusions Patent and publication data may be used to quantitatively evaluate technological innovation in neurosurgery. PMID:25699414

  6. Technological innovation in neurosurgery: a quantitative study.

    PubMed

    Marcus, Hani J; Hughes-Hallett, Archie; Kwasnicki, Richard M; Darzi, Ara; Yang, Guang-Zhong; Nandi, Dipankar

    2015-07-01

    Technological innovation within health care may be defined as the introduction of a new technology that initiates a change in clinical practice. Neurosurgery is a particularly technology-intensive surgical discipline, and new technologies have preceded many of the major advances in operative neurosurgical techniques. The aim of the present study was to quantitatively evaluate technological innovation in neurosurgery using patents and peer-reviewed publications as metrics of technology development and clinical translation, respectively. The authors searched a patent database for articles published between 1960 and 2010 using the Boolean search term "neurosurgeon OR neurosurgical OR neurosurgery." The top 50 performing patent codes were then grouped into technology clusters. Patent and publication growth curves were then generated for these technology clusters. A top-performing technology cluster was then selected as an exemplar for a more detailed analysis of individual patents. In all, 11,672 patents and 208,203 publications related to neurosurgery were identified. The top-performing technology clusters during these 50 years were image-guidance devices, clinical neurophysiology devices, neuromodulation devices, operating microscopes, and endoscopes. In relation to image-guidance and neuromodulation devices, the authors found a highly correlated rapid rise in the numbers of patents and publications, which suggests that these are areas of technology expansion. An in-depth analysis of neuromodulation-device patents revealed that the majority of well-performing patents were related to deep brain stimulation. Patent and publication data may be used to quantitatively evaluate technological innovation in neurosurgery.

  7. Proteinase K improves quantitative acylation studies.

    PubMed

    Fränzel, Benjamin; Fischer, Frank; Steegborn, Clemens; Wolters, Dirk Andreas

    2015-01-01

    Acetylation is a common PTM of proteins but is still challenging to analyze. Only few acetylome studies have been performed to tackle this issue. Yet, the detection of acetylated proteins in complex cell lysates remains to be improved. Here, we present a proteomic approach with proteinase K as a suitable protease to identify acetylated peptides quantitatively. We first optimized the digestion conditions using an artificial system of purified bovine histones to find the optimal protease. Subsequently, the capability of proteinase K was demonstrated in complex HEK293 cell lysates. Finally, SILAC in combination with MudPIT was used to show that quantification with proteinase K is possible. In this study, we identified a sheer number of 557 unique acetylated peptides originating from 633 acetylation sites. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. Spanish personal name variations in national and international biomedical databases: implications for information retrieval and bibliometric studies

    PubMed Central

    Ruiz-Pérez, R.; López-Cózar, E. Delgado; Jiménez-Contreras, E.

    2002-01-01

    Objectives: The study sought to investigate how Spanish names are handled by national and international databases and to identify mistakes that can undermine the usefulness of these databases for locating and retrieving works by Spanish authors. Methods: The authors sampled 172 articles published by authors from the University of Granada Medical School between 1987 and 1996 and analyzed the variations in how each of their names was indexed in Science Citation Index (SCI), MEDLINE, and Índice Médico Español (IME). The number and types of variants that appeared for each author's name were recorded and compared across databases to identify inconsistencies in indexing practices. We analyzed the relationship between variability (number of variants of an author's name) and productivity (number of items the name was associated with as an author), the consequences for retrieval of information, and the most frequent indexing structures used for Spanish names. Results: The proportion of authors who appeared under more then one name was 48.1% in SCI, 50.7% in MEDLINE, and 69.0% in IME. Productivity correlated directly with variability: more than 50% of the authors listed on five to ten items appeared under more than one name in any given database, and close to 100% of the authors listed on more than ten items appeared under two or more variants. Productivity correlated inversely with retrievability: as the number of variants for a name increased, the number of items retrieved under each variant decreased. For the most highly productive authors, the number of items retrieved under each variant tended toward one. The most frequent indexing methods varied between databases. In MEDLINE and IME, names were indexed correctly as “first surname second surname, first name initial middle name initial” (if present) in 41.7% and 49.5% of the records, respectively. However, in SCI, the most frequent method was “first surname, first name initial second name initial” (48.0% of

  9. Spanish personal name variations in national and international biomedical databases: implications for information retrieval and bibliometric studies.

    PubMed

    Ruiz-Pérez, R; Delgado López-Cózar, E; Jiménez-Contreras, E

    2002-10-01

    The study sought to investigate how Spanish names are handled by national and international databases and to identify mistakes that can undermine the usefulness of these databases for locating and retrieving works by Spanish authors. The authors sampled 172 articles published by authors from the University of Granada Medical School between 1987 and 1996 and analyzed the variations in how each of their names was indexed in Science Citation Index (SCI), MEDLINE, and Indice Medico Español (IME). The number and types of variants that appeared for each author's name were recorded and compared across databases to identify inconsistencies in indexing practices. We analyzed the relationship between variability (number of variants of an author's name) and productivity (number of items the name was associated with as an author), the consequences for retrieval of information, and the most frequent indexing structures used for Spanish names. The proportion of authors who appeared under more then one name was 48.1% in SCI, 50.7% in MEDLINE, and 69.0% in IME. Productivity correlated directly with variability: more than 50% of the authors listed on five to ten items appeared under more than one name in any given database, and close to 100% of the authors listed on more than ten items appeared under two or more variants. Productivity correlated inversely with retrievability: as the number of variants for a name increased, the number of items retrieved under each variant decreased. For the most highly productive authors, the number of items retrieved under each variant tended toward one. The most frequent indexing methods varied between databases. In MEDLINE and IME, names were indexed correctly as "first surname second surname, first name initial middle name initial" (if present) in 41.7% and 49.5% of the records, respectively. However, in SCI, the most frequent method was "first surname, first name initial second name initial" (48.0% of the records) and first surname and second

  10. Global research production in glyphosate intoxication from 1978 to 2015: A bibliometric analysis.

    PubMed

    Zyoud, S H; Waring, W S; Al-Jabi, S W; Sweileh, W M

    2017-10-01

    Glyphosate (N-phosphonomethylglycine) has been used as a broad-spectrum herbicide that has been widely used in the agricultural industry and also available for home use. The main aim of this study is to present a general overview of glyphosate intoxication-related publications from its introducing since the early 1970s using bibliometric technique. On June 23, 2016, a literature search of the Scopus database was performed. We then extracted and analyzed the data using well-established qualitative and quantitative bibliometric indices: Publication year, affiliation, document type, country name, subject category, journal name, publishing language, and collaboration and citation patterns. We recognized a total of 3735 publications on glyphosate published between 1973 and 2015. There were 875 publications related to glyphosate intoxication in the Scopus database published between 1978 and 2015. Articles (757) comprised 86.5% of the total publications, followed by reviews (41; 4.7%). Most publications were published in English (87.9%), followed by Portuguese (6.6%). The number of publications related to glyphosate intoxication increased from 44 in 1978-1987 up to 152 in 1996-2005 and then quadrupled in 2006-2015. The United States was the leading country with 180 documents representing 20.6%, followed by Brazil (120; 13.7%), Canada (78; 8.9%), Argentina (61; 7.0%), and France (57; 6.5%). The 85.6% of the publications was cited, and the average of citation per document was 17.13 with h-index of 55. Furthermore, the United States achieved the highest h-index of 33. Most of the global international collaborations are made with researchers from the United States, who collaborated with 23 countries/territories in 44 publications. The trends in global glyphosate-related research between 1978 and 2015 were evaluated by a bibliometric technique. Results showed that English was the leading publishing language, and the major publication type was original article. Findings showed

  11. The bibliometrics of atmospheric environment

    NASA Astrophysics Data System (ADS)

    Brimblecombe, Peter; Grossi, Carlota M.

    Bibliometric analysis is an important tool in the management of a journal. SCOPUS output is used to assess the increase in the quantity of material in Atmospheric Environment and stylistic changes in the way authors choose words and punctuation in titles and assemble their reference lists. Citation analysis is used to consider the impact factor of the journal, but perhaps more importantly the way in which it reflects the importance authors give to papers published in Atmospheric Environment. The impact factor of Atmospheric Environment (2.549 for 2007) from the Journal Citation Reports suggests it performs well within the atmospheric sciences, but it conceals the long term value authors place on papers appearing in the journal. Reference lists show that a fifth come through citing papers more than a decade old.

  12. Do Standard Bibliometric Measures Correlate with Academic Rank of Full-Time Pediatric Dentistry Faculty Members?

    PubMed

    Susarla, Harlyn K; Dhar, Vineet; Karimbux, Nadeem Y; Tinanoff, Norman

    2017-04-01

    The aim of this cross-sectional study was to assess the relationship between quantitative measures of research productivity and academic rank for full-time pediatric dentistry faculty members in accredited U.S. and Canadian residency programs. For each pediatric dentist in the study group, academic rank and bibliometric factors derived from publicly available databases were recorded. Academic ranks were lecturer/instructor, assistant professor, associate professor, and professor. Bibliometric factors were mean total number of publications, mean total number of citations, maximum number of citations for a single work, and h-index (a measure of the impact of publications, determined by total number of publications h that had at least h citations each). The study sample was comprised of 267 pediatric dentists: 4% were lecturers/instructors, 44% were assistant professors, 30% were associate professors, and 22% were professors. The mean number of publications for the sample was 15.4±27.8. The mean number of citations was 218.4±482.0. The mean h-index was 4.9±6.6. The h-index was strongly correlated with academic rank (r=0.60, p=0.001). For this sample, an h-index of ≥3 was identified as a threshold for promotion to associate professor, and an h-index of ≥6 was identified as a threshold for promotion to professor. The h-index was strongly correlated with the academic rank of these pediatric dental faculty members, suggesting that this index may be considered a measure for promotion, along with a faculty member's quality and quantity of research, teaching, service, and clinical activities.

  13. Worldwide research productivity on tramadol: a bibliometric analysis.

    PubMed

    Sweileh, Waleed M; Shraim, Naser Y; Zyoud, Sa'ed H; Al-Jabi, Samah W

    2016-01-01

    Pain management and safe use of analgesics is an important medical issue. Tramadol is an old analgesic with controversial properties. Evaluation of worldwide scientific output on tramadol has not been explored. Therefore, the main objective of this study was to give a bibliometric overview of global research productivity on tramadol. SciVerse Scopus was used to retrieve and quantitatively and qualitatively analyze worldwide publications on tramadol. A total of 2059 original and review research articles on tramadol were retrieved from Scopus. Forty-six documents (2.23 %) were published in Anesthesia and Analgesia Journal whereas 30 (1.46 %) were published in Arzneimittel Forschung Drug Research Journal. Retrieved tramadol documents were published from 71 countries and appeared in 160 peer reviewed journals. Although the United States of America (259; 12.86 %) had the largest contribution to tramadol publications; the contribution by other countries like Turkey (232; 11.27) India (189; 8.09 %) and Germany (176; 8.56 % was not far away from that of USA. The most productive institution was Grunenthal, Germany (47; 2.28 %) followed by Tehran University of Medical Sciences, Iran (29; 1.41 %), and, Ortho-McNeil Pharmaceutical Incorporated, USA (25; 1.21 %). Of the 2059 documents, there were 370 documents about dependence. The leading institution in documents pertaining to tramadol dependence was Grunenthal GmbH (18; 4.86 %) followed by Ortho-McNeil Pharmaceutical Incorporated (17; 4.59 %). The current study showed that there is an obvious interest in tramadol research. More efforts are needed to clarify the abuse potential and safety profile of tramadol to help in determining the legal status of tramadol. Collaboration among pharmaceutical industry, clinical researchers and academic institutions can improve research quantity and quality on tramadol.

  14. An analysis of bibliometric indicators to JCR according to Benford's law.

    PubMed

    Alves, Alexandre Donizeti; Yanasse, Horacio Hideki; Soma, Nei Yoshihiro

    Journal Citation Reports (JCR) is the main source of bibliometric indicators known by the scientific community. This paper presents the results of a study of the distributions of the first and second significant digits according to Benford's law (BL) of the number of articles, citations, impact factors, half-life and immediacy index bibliometric indicators in journals indexed in the JCR Sciences and Social Sciences Editions from 2007 to 2014. We also performed the data analysis to country's origin and by journal's category, and we verified that the second digit has a better adherence to BL. The use of the second digit is important since it provides a more sound, complete and consistent analysis of the bibliometric indicators.

  15. Hailpad-based research: A bibliometric review

    NASA Astrophysics Data System (ADS)

    Palencia, Covadonga; Castro, Amaya; Giaiotti, Dario; Stel, Fulvio; Vinet, Freddy; Fraile, Roberto

    This paper is an overview of hailpad research from its origin until today using as a search criterion the bibliographic references on the subject in the Web of Science database (ISI). The search was carried out on 1st September 2008. Among the more than 3·10 7 scientific documents included in the Science Citation Index Expanded (SCI-EXPANDED) from 1945 to the present, the search engine identified 41 containing the word "hailpad*" (the asterisk is a wildcard for any letter or group of letters). The results have been analyzed according to various criteria: countries with hailpad networks or studies on hailpads; date of the first article; evolution of the number of articles per decade; concepts studied and research lines followed in each article; and finally, a bibliometric analysis of the journals where these articles have been published. It was found that 70% of the articles on hailpads were published in 2 journals: Journal of Applied Meteorology and Atmospheric Research. These two journals also concentrate most of the citations. The number of articles on hailpads and the documents that cite them have grown steadily, and it is expected to grow still further in the present decade if we take into account the trends found.

  16. [Scientometrics and bibliometrics of chronotherapy].

    PubMed

    Zhao, Ping; Xu, Ping; Li, Bingyan; Wang, Zhengrong

    2005-02-01

    In order to retrieve Chinese and foreign articles of chronotherapy, we searched Chinese databases of CBM, CMCC and foreign series databases in OVID and hence revealed and assessed the current status, research trend and level of chronotherapy in China and in foreign countries by means of scientometric and bibliometric parameters. ProCite5 software and handsearching were used to manage, check and statistically analyze the searched papers so as to find the parameters which included distributions of databases, years, authors, periodicals, subject headings, organizations and nations. 91 Chinese papers were identified which were distributed in 73 kinds of journals and in subject headings, e.g., Traditional Chinese medicine, cardiovascular diseases, neoplasms, asthma, peptic ulcer, diabetes mellitus, general review of chronotherapy, etc. 480 foreign articles were identified which mainly came from EMBASE and MEDLINE and were distributed in 285 types of journals and 35 nations and regions. There were 14 journals which recorded five or more articles. 12 researchers published more than five articles. Paul Brousse Hospital, University of Texas, University of Connecticut School of Medicine, Jichi Medical School and University of Minnesota were the core research institutes. There was no core author or core journal or core institute in China up till now. However, core authors, core journals and core research institutes had come into being in foreign countries; they were mainly from the Euro-American developed countries and had done well in chronotherapy.

  17. Subjective Quantitative Studies of Human Agency

    ERIC Educational Resources Information Center

    Alkire, Sabina

    2005-01-01

    Amartya Sen's writings have articulated the importance of human agency, and identified the need for information on agency freedom to inform our evaluation of social arrangements. Many approaches to poverty reduction stress the need for empowerment. This paper reviews "subjective quantitative measures of human agency at the individual level." It…

  18. Quantitative analysis of the scientific literature on acetaminophen in medicine and biology: a 2003-2005 study.

    PubMed

    Robert, Claude; Saenz-Feijoo, Rosa; Gaudy, Jean-François; Arreto, Charles-Daniel

    2009-04-01

    This study quantifies the utilization of acetaminophen in life sciences and clinical medicine using bibliometric indicators. A total of 1626 documents involving acetaminophen published by 74 countries during 2003-2005 in the Thompson-Scientific Life sciences and Clinical Medicine collections were identified and analyzed. The USA leads in the number of publications followed by the UK, and industrialized countries, including France, Japan and Germany; the presence of countries such as China, India and Turkey among the top 15 countries deserves to be noticed. The European Union stands as a comparable contributor to the USA, both in terms of number of publications and in terms of profile of papers distributed among subcategories of Life Sciences and Clinical Medicine disciplines. All documents were published in 539 different journals. The most prolific journals were related to pharmacology and/or pharmaceutics. All aspects of acetaminophen (chemistry, pharmacokinetics, metabolism, etc.) were studied with primary interest for therapeutic use (42%) and adverse effects (28%) comprising a large part of publications focusing on acetaminophen hepatotoxicity. This quantitative overview provides as to the interest of the scientific community in this analgesic and completes the various review documents that regularly appear in the scientific literature.

  19. Bibliometric Assessment of the Global Scientific Production of Nitazoxanide

    PubMed Central

    Martinez-Pulgarin, Dayron F; Muñoz-Urbano, Marcela; Gómez-Suta, Daniela; Sánchez-Duque, Jorge A; Machado-Alba, Jorge E

    2017-01-01

    Introduction Nitazoxanide is a member of a new class of drug, thiazolides, and it was discovered in 1984 with antimicrobial activity effect against anaerobic bacteria, Hepatitis virus, protozoa, and helminths. Methods A bibliometric study on four databases (1984-2016) – Medline, Scopus, LILACS, and SciELO – characterizing the global scientific production of nitazoxanide. We determined the quantity, quality (number of citations), and types of studies developed by each country, characterizing them by years, international cooperation, development, place of publication, authors (with its H-index), and groups with higher impact. Results There were 512 articles in Medline – the higher scientific production is from the USA (19.71%), Switzerland (7.51%), and Mexico (7.27%). There were 1,440 articles in Scopus – from the USA (8.98%), Mexico (2.13%), and India (1.65%). There were 405 articles in LILACS – from Mexico (4.69%), the USA (4.2%), and Peru (2.47%). There were 47 articles in SciELO – from Brazil (34.04%), Venezuela (21.28%), and Colombia (14.89%). The H-index of nitazoxanide is 75 – the USA (26), Egypt (12), and Canada (10) were the countries contributing more with that. Conclusions Nitazoxanide research has been highly important. Nevertheless, it is relatively limited when compared with other drugs. Its research has been led by the USA, as revealed in this bibliometric assessment. Although some developing countries, where it is used especially for protozoa and helminths, probably have its influence, and this explains the fact that Mexico and India, among others, are the top countries in the scientific production of this anti-infective agent. This bibliometric study evidenced a relatively low number of publications, however, it has been increased in recent years. PMID:28580201

  20. Bibliometric Assessment of the Global Scientific Production of Nitazoxanide.

    PubMed

    Rodriguez-Morales, Alfonso J; Martinez-Pulgarin, Dayron F; Muñoz-Urbano, Marcela; Gómez-Suta, Daniela; Sánchez-Duque, Jorge A; Machado-Alba, Jorge E

    2017-05-01

    Nitazoxanide is a member of a new class of drug, thiazolides, and it was discovered in 1984 with antimicrobial activity effect against anaerobic bacteria, Hepatitis virus, protozoa, and helminths. A bibliometric study on four databases (1984-2016) - Medline, Scopus, LILACS, and SciELO - characterizing the global scientific production of nitazoxanide. We determined the quantity, quality (number of citations), and types of studies developed by each country, characterizing them by years, international cooperation, development, place of publication, authors (with its H-index), and groups with higher impact. There were 512 articles in Medline - the higher scientific production is from the USA (19.71%), Switzerland (7.51%), and Mexico (7.27%). There were 1,440 articles in Scopus - from the USA (8.98%), Mexico (2.13%), and India (1.65%). There were 405 articles in LILACS - from Mexico (4.69%), the USA (4.2%), and Peru (2.47%). There were 47 articles in SciELO - from Brazil (34.04%), Venezuela (21.28%), and Colombia (14.89%). The H-index of nitazoxanide is 75 - the USA (26), Egypt (12), and Canada (10) were the countries contributing more with that. Nitazoxanide research has been highly important. Nevertheless, it is relatively limited when compared with other drugs. Its research has been led by the USA, as revealed in this bibliometric assessment. Although some developing countries, where it is used especially for protozoa and helminths, probably have its influence, and this explains the fact that Mexico and India, among others, are the top countries in the scientific production of this anti-infective agent. This bibliometric study evidenced a relatively low number of publications, however, it has been increased in recent years.

  1. Bibliometric indexes, databases and impact factors in cardiology

    PubMed Central

    Bienert, Igor R C; de Oliveira, Rogério Carvalho; de Andrade, Pedro Beraldo; Caramori, Carlos Antonio

    2015-01-01

    Bibliometry is a quantitative statistical technique to measure levels of production and dissemination of knowledge, as well as a useful tool to track the development of an scientific area. The valuation of production required for recognition of researchers and magazines is accomplished through tools called bibliometricindexes, divided into quality indicators and scientific impact. Initially developed for monographs of statistical measures especially in libraries, today bibliometrics is mainly used to evaluate productivity of authors and citation repercussion. However, these tools have limitations and sometimes provoke controversies about indiscriminate application, leading to the development of newer indexes. It is important to know the most common search indexes and use it properly even acknowledging its limitations as it has a direct impact in their daily practice, reputation and funds achievement. PMID:26107458

  2. Bibliometrics as weapons of mass citation.

    PubMed

    Molinié, Antoinette; Bodenhausen, Geoffrey

    2010-01-01

    The allocation of resources for research is increasingly based on so-called 'bibliometrics'. Scientists are now deemed to be successful on the sole condition that their work be abundantly cited. This world-wide trend appears to enjoy support not only by granting agencies (whose task is obviously simplified by extensive recourse to bibliometrics), but also by the scientists themselves (who seem to enjoy their status of celebrities). This trend appears to be fraught with dangers, particularly in the area of social sciences, where bibliometrics are less developed, and where monographs (which are not taken into account in citation indexes) are often more important than articles published in journals. We argue in favour of a return to the values of 'real science', in analogy to the much-promised return to a 'real economy'. While economists may strive towards a more objective evaluation of the prospects of a company, a market, or an industrial sector, we scientists can only base our appraisal on a responsible practice of peer review. Since we fear that decision-takers of granting agencies such as the FNRS, CTI, EPFL, ETHZ, ANR, CNRS, NIH, NSF, DOE, etc. will be too busy to read our humble paper in Chimia, we appeal to scientists of all countries and disciplines to unite against the tyranny of bibliometrics.

  3. A Bibliometric Distribution Which Really Works.

    ERIC Educational Resources Information Center

    Sichel, H. S.

    1985-01-01

    The Generalized Inverse Gaussian-Poisson Distribution is suggested as an all-embracing mathematical model for bibliometric frequency distributions. Twelve examples are given which show that the new model cannot be rejected by virtue of an objective chi-squared test. A mathematical appendix and 20 references are included. (Author/EJS)

  4. Bibliometrics: Help or Hoax for Quality?

    ERIC Educational Resources Information Center

    Galetto, F.

    2014-01-01

    Higher Education Institutions should provide students good teaching with good professors who have good knowledge of the matter they are teaching. Unfortunately, many times, the opposite happens: career leaps depend on "bibliometric indexes" (Impact Points, "h"-index, "s"-index, "RG"-index,…

  5. Bibliometrics/Theory, Practice and Problems.

    ERIC Educational Resources Information Center

    Narin, Francis; And Others

    1994-01-01

    Theory behind modern evaluative bibliometric techniques is reviewed at three levels: (1) policy application; (2) strategic analysis; and (3) tactical analysis. New techniques developed at each level and limitations of each approach are discussed. At all levels, the process begins with assembling data and then moves to a data-based evaluation. (SLD)

  6. Understanding Scientific Literatures: A Bibliometric Approach.

    ERIC Educational Resources Information Center

    Donohue, Joseph C.

    To operate effectively, libraries must develop methods by which to identify literatures of high utility to their clientele and must acquire and organize these literatures in such a way as to optimize their usefulness. One such method, the bibliometric approach, is based on the assumption of certain regularities in patterns of authorship,…

  7. Citation Mining: Integrating Text Mining and Bibliometrics for Research User Profiling.

    ERIC Educational Resources Information Center

    Kostoff, Ronald N.; del Rio, J. Antonio; Humenik, James A.; Garcia, Esther Ofilia; Ramirez, Ana Maria

    2001-01-01

    Discusses the importance of identifying the users and impact of research, and describes an approach for identifying the pathways through which research can impact other research, technology development, and applications. Describes a study that used citation mining, an integration of citation bibliometrics and text mining, on articles from the…

  8. Growth or Steady State? A Bibliometric Focus on International Comparative Higher Education Research

    ERIC Educational Resources Information Center

    Kosmützky, Anna; Krücken, Georg

    2014-01-01

    The study combines a bibliometric approach with a content analysis of abstracts of articles to explore the patterns of international comparative higher education research in leading international journals. The overall data set covers 4,095 publications from the Web of Science for the period 1992-2012 and the amount of international comparative…

  9. The Non-Gaussian Nature of Bibliometric and Scientometric Distributions: A New Approach to Interpretation.

    ERIC Educational Resources Information Center

    Ivancheva, Ludmila E.

    2001-01-01

    Discusses the concept of the hyperbolic or skew distribution as a universal statistical law in information science and socioeconomic studies. Topics include Zipf's law; Stankov's universal law; non-Gaussian distributions; and why most bibliometric and scientometric laws reveal characters of non-Gaussian distribution. (Author/LRW)

  10. Attitudes towards Disability in Education through the SSCI (2000-2011): A Topical and Bibliometric Analysis

    ERIC Educational Resources Information Center

    Garcia-Fernandez, Jose Manuel; Ingles, Candido J.; Juan, Maria Vicent; Gonzalvez-Macia, Carolina; Manas-Viejo, Carmen

    2013-01-01

    Introduction: The purpose of this study is to describe and characterize the international scientific output relating to "attitudes towards disability in education", using a battery of bibliometric indicators that make it possible to analyze and monitor international scientific activity. Method: This "ex post facto"…

  11. High-Impact Social Work Scholars: A Bibliometric Examination of SSWR and AASWSW Fellows

    ERIC Educational Resources Information Center

    Hodge, David R.; Kremer, Kristen P.; Vaughn, Michael G.

    2016-01-01

    Objective: The purpose of this study was to identify and describe the bibliometric contributions of high-impact social work faculty. Methods: Toward this end, we used a sample comprising fellows (N = 143) affiliated with the Society for Social Work and Research (SSWR) and the American Academy of Social Work and Social Welfare (AASWSW). To quantify…

  12. Relationships between Association of Research Libraries (ARL) Statistics and Bibliometric Indicators: A Principal Components Analysis

    ERIC Educational Resources Information Center

    Hendrix, Dean

    2010-01-01

    This study analyzed 2005-2006 Web of Science bibliometric data from institutions belonging to the Association of Research Libraries (ARL) and corresponding ARL statistics to find any associations between indicators from the two data sets. Principal components analysis on 36 variables from 103 universities revealed obvious associations between…

  13. A Bibliometric Snapshot of "The Journal of Higher Education" and Its Impact on the Field

    ERIC Educational Resources Information Center

    Earp, Vanessa J.

    2010-01-01

    In recent decades the field of higher education has grown exponentially; however, little research examines a particular journal and its impact on the field. The purpose of this study was to conduct a brief bibliometric analysis and discuss the impact of "The Journal of Higher Education" (1998-2002), a premier journal in the discipline. (Contains 6…

  14. Research Productivity and Performance of Journals in the Creativity Sciences: A Bibliometric Analysis

    ERIC Educational Resources Information Center

    Long, Haiying; Plucker, Jonathan A.; Yu, Qi; Ding, Ying; Kaufman, James C.

    2014-01-01

    A bibliometric approach was employed to analyze the research productivity and performance of creativity studies between 1965 and 2012. A dataset was constructed using all publications and citations retrieved from four key journals that publish creativity research: "Journal of Creative Behavior" ("JCB"), "Gifted Child…

  15. Attitudes towards Disability in Education through the SSCI (2000-2011): A Topical and Bibliometric Analysis

    ERIC Educational Resources Information Center

    Garcia-Fernandez, Jose Manuel; Ingles, Candido J.; Juan, Maria Vicent; Gonzalvez-Macia, Carolina; Manas-Viejo, Carmen

    2013-01-01

    Introduction: The purpose of this study is to describe and characterize the international scientific output relating to "attitudes towards disability in education", using a battery of bibliometric indicators that make it possible to analyze and monitor international scientific activity. Method: This "ex post facto"…

  16. High-Impact Social Work Scholars: A Bibliometric Examination of SSWR and AASWSW Fellows

    ERIC Educational Resources Information Center

    Hodge, David R.; Kremer, Kristen P.; Vaughn, Michael G.

    2016-01-01

    Objective: The purpose of this study was to identify and describe the bibliometric contributions of high-impact social work faculty. Methods: Toward this end, we used a sample comprising fellows (N = 143) affiliated with the Society for Social Work and Research (SSWR) and the American Academy of Social Work and Social Welfare (AASWSW). To quantify…

  17. Citation Mining: Integrating Text Mining and Bibliometrics for Research User Profiling.

    ERIC Educational Resources Information Center

    Kostoff, Ronald N.; del Rio, J. Antonio; Humenik, James A.; Garcia, Esther Ofilia; Ramirez, Ana Maria

    2001-01-01

    Discusses the importance of identifying the users and impact of research, and describes an approach for identifying the pathways through which research can impact other research, technology development, and applications. Describes a study that used citation mining, an integration of citation bibliometrics and text mining, on articles from the…

  18. Growth or Steady State? A Bibliometric Focus on International Comparative Higher Education Research

    ERIC Educational Resources Information Center

    Kosmützky, Anna; Krücken, Georg

    2014-01-01

    The study combines a bibliometric approach with a content analysis of abstracts of articles to explore the patterns of international comparative higher education research in leading international journals. The overall data set covers 4,095 publications from the Web of Science for the period 1992-2012 and the amount of international comparative…

  19. A Methodological Approach to Developing Bibliometric Models of Types of Humanities Scholarship.

    ERIC Educational Resources Information Center

    Wiberley, Stephen E., Jr.

    2003-01-01

    Outlines a methodological approach to developing bibliometric models of the sources used in different types of humanities scholarship. Identifies five types of scholarship: description of primary sources, editing of primary sources, historical studies, criticism, and theory. Illustrates the approach through an analysis of sources used in 54…

  20. Relationships between Association of Research Libraries (ARL) Statistics and Bibliometric Indicators: A Principal Components Analysis

    ERIC Educational Resources Information Center

    Hendrix, Dean

    2010-01-01

    This study analyzed 2005-2006 Web of Science bibliometric data from institutions belonging to the Association of Research Libraries (ARL) and corresponding ARL statistics to find any associations between indicators from the two data sets. Principal components analysis on 36 variables from 103 universities revealed obvious associations between…

  1. Quantitative Articles: Developing Studies for Publication in Counseling Journals

    ERIC Educational Resources Information Center

    Trusty, Jerry

    2011-01-01

    This article is presented as a guide for developing quantitative studies and preparing quantitative manuscripts for publication in counseling journals. It is intended as an aid for aspiring authors in conceptualizing studies and formulating valid research designs. Material is presented on choosing variables and measures and on selecting…

  2. Quantitative Articles: Developing Studies for Publication in Counseling Journals

    ERIC Educational Resources Information Center

    Trusty, Jerry

    2011-01-01

    This article is presented as a guide for developing quantitative studies and preparing quantitative manuscripts for publication in counseling journals. It is intended as an aid for aspiring authors in conceptualizing studies and formulating valid research designs. Material is presented on choosing variables and measures and on selecting…

  3. Quantitative assessment of scientific quality

    NASA Astrophysics Data System (ADS)

    Heinzl, Harald; Bloching, Philipp

    2012-09-01

    Scientific publications, authors, and journals are commonly evaluated with quantitative bibliometric measures. Frequently-used measures will be reviewed and their strengths and weaknesses will be highlighted. Reflections about conditions for a new, research paper-specific measure will be presented.

  4. Quantitative Literacy Provision in the First Year of Medical Studies

    ERIC Educational Resources Information Center

    Frith, V.

    2011-01-01

    This article presents a description of and motivation for the quantitative literacy (numeracy) intervention in the first year of medical studies at a South African university. This intervention is a response to the articulation gap between the quantitative literacy of many first-year medical students and the demands of their curriculum.…

  5. Quantitative Literacy Provision in the First Year of Medical Studies

    ERIC Educational Resources Information Center

    Frith, V.

    2011-01-01

    This article presents a description of and motivation for the quantitative literacy (numeracy) intervention in the first year of medical studies at a South African university. This intervention is a response to the articulation gap between the quantitative literacy of many first-year medical students and the demands of their curriculum.…

  6. [Bibliometric indicators of production and usage of Archivos de Bronchoneumologia].

    PubMed

    García Río, F; Serrano, S; Alvarez-Sala, R; García Tejero, T; Pino García, J; Alvarez-Sala, J L; Villamor León, J

    1996-01-01

    We studied the bibliometric indexes referring to production and scientific output published in ARCHIVOS de BRONCONEUMOLOGIA. All issues published between 1993 and 1994 were studied with the exception of monógraphic or supplementary numbers. For each article we recorded article type, number of authors, authors' place of work, specialty, time until acceptance, time until publication, type of references, language of references, journal and year of references. For each year we calculated the productivity index and the cooperation index, or index of signers per work. We also determined the citation period for references, the Price index, and the insularity index. Productivity index was 1.97 in 1993 and 2.05 in 1994. The cooperation index for the two years reached 4.5 +/- 1.9 (1-10). Authors were widely distributed by provinces and by specialties, although "nuclei" of production could be identified. The citation half-life period was 5.67 years for references in 1993 and 5.94 years in 1994, and the Price index surpassed 40%. The insularity index was very low at 7.76%. In conclusion, the bibliometric indicators for production, readership and obsolescence for the two years analyzed indicate that ARCHIVOS de BRONCONEUMOLOGIA occupies an intermediate position in the ranking of Spanish medical journals.

  7. Bibliometric Patterns of Research Literature Production on Nursing Informatics Competence.

    PubMed

    Kokol, Peter; Blažun Vošner, Helena; Železnik, Danica; Vošner, Janez; Saranto, Kaija

    2015-10-01

    Nursing informatics competence is a prerequisite for successful information management, evidence-based practices optimizing patient care health promotion, and communication with information communication technology-literate patients. The aim of this study was to assess the trends in the production of nursing informatics competence research literature and to identify the most productive bibliometric entities. In addition to the correspondence analysis, bibliometric analysis and mapping were used to achieve the aim. A total of 366 information sources were extracted, 14.5% of which were sponsored studies. The production of research literature on nursing informatics competence is growing, but this research is only occasionally published in the most recognized nursing journals. Identifying where the intensive research on nursing informatics competence is beneficial to care for the patient of the future and building user-friendly online lifelong learning platforms, where a required level of nursing informatics competence could be acquired, are two gaps in the current research that should be covered in future. Copyright 2015, SLACK Incorporated.

  8. Environmental health research in Europe: bibliometric analysis.

    PubMed

    Tarkowski, S M

    2007-01-01

    This article describes a bibliometric review of the environmental health research literature in Europe for a period of 10 years. The work, within the study SPHERE (Strengthening Public Health Research in Europe) aimed to provide an overview of the extent of published environmental health research in Europe and to assess recent output in this research field and future research direction. Medline was used via the PubMed online service of the US National Library of Medicine. Only original, peer-reviewed research journal articles were retrieved, which were published from mid-1995 to mid-2005 and by authors from the 28 (then) countries in Europe of the European Economic Area plus Switzerland. In the PubMed database, 6329 references were located and were allocated to 11 pre-defined topic areas and 31 subtopic areas. The largest number of articles was in the topic area of work environment and health (2339) followed by environmental exposures (1314) and environmental illnesses (952) and these were the primary foci of 73% of the published articles. There were marked differences between countries in the number of published articles. Ten countries contributed 81% of all publications. It is apparent that economic factors have a major role for research outputs of countries in environmental health. Major advances have been made during recent years in the understanding of associations between health and environment, and of biological, environmental and social mechanisms involved in this association. More emphasis should be placed on investigations of complex environmental health problems such as complex exposures to different pollutants at different levels and their combined health impact in different populations.

  9. Content and bibliometric analysis of articles published in the Journal of Orthopaedic & Sports Physical Therapy.

    PubMed

    Coronado, Rogelio A; Wurtzel, Wendy A; Simon, Corey B; Riddle, Daniel L; George, Steven Z

    2011-12-01

    Descriptive bibliometric analysis. Content and bibliometric studies are useful for describing the publication patterns of a given profession, such as physical therapy, within the medical and allied health fields. However, few studies have conducted these analyses on specialty physical therapy journals. To conduct a content and bibliometric assessment of publications within the Journal of Orthopaedic & Sports Physical Therapy (JOSPT) and report publication and citation trends over multiple years. All available JOSPT manuscripts published from 1980 through 2009 were reviewed. Only research reports, topical reviews, and case reports were included in the current analysis. Articles were coded by 2 independent reviewers based on type, participant characteristics, research design, purpose, clinical condition, and intervention. We obtained additional citation information (eg, authors and institutions) from a subset of articles published from 1992 through 2009 using bibliometric software. Of the 2233 available JOSPT publications, 1732 (77.6%) met criteria for inclusion. Of these, 1172 (67.7%) were research reports, 351 (20.3%) topical reviews, and 209 (12.1%) case reports. Over the last 30 years there has been a significant increase in the number of articles published and the percentage of research reports, systematic reviews, articles focused on prognosis, and articles including symptomatic participants. Percentage decreases were observed for topical or nonsystematic reviews and articles focused on anatomy/physiology. Top institutions, authors, and cited papers from 1992 through 2009 were identified in the bibliometric analyses. JOSPT has shown publication trends for increased percentage of experimental and clinically relevant research. However, there may be a need for increased publication of randomized controlled trials and studies focused on diagnosis, prognosis, and treatment, if goals of evidence-based practice are to be met.

  10. Geodesy, a Bibliometric Approach for 2000-2006

    NASA Astrophysics Data System (ADS)

    Vazquez, G.; Landeros, C. F.

    2007-12-01

    In recent years, bibliometric science has been frequently applied in the development and evaluation of scientific research. This work presents a bibliometric analysis for the research work performed in the field of geodesy "science of the measurement and mapping of the earth surface including its external gravity field". The objective of this work is to present a complete overview of the generated research on this field to assemble and study the most important publications occurred during the past seven years. The analysis was performed including the SCOPUS and WEB OF SCIENCE databases for all the geodetic scientific articles published between 2000 and 2006. The search profile was designed considering a strategy to seek for titles and article descriptors using the terms geodesy and geodetic and some other terms associated with the topics: geodetic surfaces, vertical measurements, reference systems and frames, modern space-geodetic techniques and satellite missions. Some preliminary results had been achieved specifically Bradford law of distribution for journals and education institutes, and Lotka's law for authors that also includes the cooperation between countries in terms of writing together scientific articles. In the particular case of distributions, the model suggested by Egghe (2002) was adopted for determining the cores.

  11. A bibliometric analysis of research productivity of emergency medicine researchers in South Korea

    PubMed Central

    Choi, Jiun; You, Je Sung; Joo, Young Seon; kong, Taeyoung; Ko, Dong Ryul; Chung, Sung Phil

    2016-01-01

    Objective During the past 20 years, over 1,400 doctors have been certified as emergency physicians in Korea. The number of scientific publications in the field of emergency medicine has also increased. This study aims to evaluate the research productivity of academic emergency physicians in South Korea. Methods Articles published from 1996 to 2015 by authors affiliated with Korean emergency departments were retrieved using Pubmed, Embase, and Web of Science. Research productivity was analyzed quantitatively to ascertain the number of articles for publication type and year. The performance of these articles was also analyzed qualitatively using impact factor, citation number, and Hirsch index. Bibliometric analysis was performed by researching Web of Science, Scopus, and Google Scholar. Results A total of 858 articles with 293 Korean authors as the first or corresponding authors were published across 191 journals. The number of publications increased continuously. The most common publication type was original article (n=618), the most commonly studied research topic was resuscitation medicine (n=110), and the average impact factor of the original articles was 2.158. The highest h-index was 17 and, using Web of Science, the maximum number of citations was found to be 85. Conclusion This study suggests that the research productivity of Korean authors in the emergency medicine field has progressed steadily during the last 10 years. However, qualitative indexes, such as the number of citations and h-index value, remain low. PMID:28168231

  12. A Bibliometric Analysis of U.S.-Based Research on the Behavioral Risk Factor Surveillance System

    PubMed Central

    Khalil, George M.; Gotway Crawford, Carol A.

    2017-01-01

    Background Since Alan Pritchard defined bibliometrics as “the application of statistical methods to media of communication” in 1969, bibliometric analyses have become widespread. To date, however, bibliometrics has not been used to analyze publications related to the U.S. Behavioral Risk Factor Surveillance System (BRFSS). Purpose To determine the most frequently cited BRFSS-related topical areas, institutions, and journals. Methods A search of the Web of Knowledge database in 2013 identified U.S.-published studies related to BRFSS, from its start in 1984 through 2012. Search terms were BRFSS, Behavioral Risk Factor Surveillance System, or Behavioral Risk Survey. The resulting 1,387 articles were analyzed descriptively and produced data for VOSviewer, a computer program that plotted a relevance distance–based map and clustered keywords from text in titles and abstracts. Results Topics, journals, and publishing institutions ranged widely. Most research was clustered by content area, such as cancer screening, access to care, heart health, and quality of life. The American Journal of Preventive Medicine and American Journal of Public Health published the most BRFSS-related papers (95 and 70, respectively). Conclusions Bibliometrics can help identify the most frequently published BRFSS-related topics, publishing journals, and publishing institutions. BRFSS data are widely used, particularly by CDC and academic institutions such as the University of Washington and other universities hosting top-ranked schools of public health. Bibliometric analysis and mapping provides an innovative way of quantifying and visualizing the plethora of research conducted using BRFSS data and summarizing the contribution of this surveillance system to public health. PMID:25442231

  13. A bibliometric analysis of U.S.-based research on the Behavioral Risk Factor Surveillance System.

    PubMed

    Khalil, George M; Gotway Crawford, Carol A

    2015-01-01

    Since Alan Pritchard defined bibliometrics as "the application of statistical methods to media of communication" in 1969, bibliometric analyses have become widespread. To date, however, bibliometrics has not been used to analyze publications related to the U.S. Behavioral Risk Factor Surveillance System (BRFSS). To determine the most frequently cited BRFSS-related topical areas, institutions, and journals. A search of the Web of Knowledge database in 2013 identified U.S.-published studies related to BRFSS, from its start in 1984 through 2012. Search terms were BRFSS, Behavioral Risk Factor Surveillance System, or Behavioral Risk Survey. The resulting 1,387 articles were analyzed descriptively and produced data for VOSviewer, a computer program that plotted a relevance distance-based map and clustered keywords from text in titles and abstracts. Topics, journals, and publishing institutions ranged widely. Most research was clustered by content area, such as cancer screening, access to care, heart health, and quality of life. The American Journal of Preventive Medicine and American Journal of Public Health published the most BRFSS-related papers (95 and 70, respectively). Bibliometrics can help identify the most frequently published BRFSS-related topics, publishing journals, and publishing institutions. BRFSS data are widely used, particularly by CDC and academic institutions such as the University of Washington and other universities hosting top-ranked schools of public health. Bibliometric analysis and mapping provides an innovative way of quantifying and visualizing the plethora of research conducted using BRFSS data and summarizing the contribution of this surveillance system to public health. Copyright © 2015 American Journal of Preventive Medicine. All rights reserved.

  14. A correlation between National Institutes of Health funding and bibliometrics in neurosurgery.

    PubMed

    Venable, Garrett T; Khan, Nickalus R; Taylor, Douglas R; Thompson, Clinton J; Michael, L Madison; Klimo, Paul

    2014-01-01

    The relationship between metrics, such as the h-index, and the ability of researchers to generate funding has not been previously investigated in neurosurgery. This study was performed to determine whether a correlation exists between bibliometrics and National Institutes of Health (NIH) funding data among academic neurosurgeons. The h-index, m-quotient, g-index, and contemporary h-index were determined for 1225 academic neurosurgeons from 99 (of 101) departments. Two databases were used to create the citation profiles, Google Scholar and Scopus. The NIH Research Portfolio Online Reporting Tools Expenditures and Reports tool was accessed to obtain career grant funding amount, grant number, year of first grant award, and calendar year of grant funding. Of the 1225 academic neurosurgeons, 182 (15%) had at least 1 grant with a fully reported NIH award profile. Bibliometric indices were all significantly higher for those with NIH funding compared to those without NIH funding (P < .001). The contemporary h-index was found to be significantly predictive of NIH funding (P < .001). All bibliometric indices were significantly associated with the total number of grants, total award amount, year of first grant, and duration of grants in calendar years (bivariate correlation, P < .001) except for the association of m-quotient with year of first grant (P = .184). Bibliometric indices are higher for those with NIH funding compared to those without, but only the contemporary h-index was shown to be predictive of NIH funding. Among neurosurgeons with NIH funding, higher bibliometric scores were associated with greater total amount of funding, number of grants, duration of grants, and earlier acquisition of their first grant. Copyright © 2014 Elsevier Inc. All rights reserved.

  15. A bibliometric analysis of occupational therapy publications.

    PubMed

    Brown, Ted; Gutman, Sharon A; Ho, Yuh-Shan; Fong, Kenneth N K

    2018-01-01

    Bibliometrics involves the statistical analysis of the publications in a specific discipline or subject area. A bibliometric analysis of the occupational therapy refereed literature is needed. A bibliometric analysis was completed of the occupational therapy literature from 1991-2014, indexed in the Science Citation Index-Expanded or the Social Sciences Citation Index. Publications were searched by title, abstract, keywords, and KeyWords Plus. Total number of article citations, citations per journal, and contributions per country, individual authors, and institution were calculated. 5,315 occupational therapy articles were published in 821 journals. It appears that there is a citation window of an approximate 10-year period between the time of publication and the peak number of citations an article receives. The top three most highly cited articles were published in Developmental Medicine and Child Neurology, JAMA, and Lancet. AJOT, BJOT and AOTJ published the largest number of occupational therapy articles with the United States, Australia, and Canada producing the highest number of publications. McMaster University, the University of Queensland, and the University of Toronto were the institutions that published the largest number of occupational therapy journal articles. The occupational therapy literature is growing and the frequency of article citation is increasing.

  16. A complex systems approach to bibliometrics

    NASA Astrophysics Data System (ADS)

    Stringer, Michael J.

    Enabled by technological change, we are in the midst of a fundamental shift in how scientific information is produced and communicated. Electronic publishing, preprint archives, blogs, and wikis are emerging as possible viable alternatives to the current journal publishing and peer review system. However, these new technologies flood the environment with information, making it increasingly difficult to find the highest quality and most relevant papers. Additionally, accreditation and quality assessment of published material becomes nearly impossible for agencies interested in funding the research and development that is most likely to succeed. Recently, bibliometric tools have emerged as an effective means for the filtering, accreditation, and assessment of scholarly information. In this thesis, we approach bibliometrics from a complex systems perspective. A unique characteristic of the work presented in this thesis is that we perform empirical validation of bibliometric models using the most comprehensive bibliographic database available. Using these methods, we quantify the dynamics of citations to scientific journals, and investigate the relationship between social network position and research performance.

  17. [Quantitative study on esophageal cytology. I. Quantitative morphologic studies of normal, dysplastic and malignant squamous cells].

    PubMed

    Xiang, Y V

    1990-03-01

    On cytosmears of esophageal epithelium of individuals from high-risk area of esophageal cancer squamous epithelial cells, according to standard cytologic diagnostic criteria, can be categorized as normal, hyperplasia, severely dysplastic grade I and grade II, nearly-carcinoma and early carcinoma. Cytosmears from 60 patients, 10 for each category, were studied with a semiautomatic image analysis system. Thirteen morphologic parameters so obtained were further analyzed by computer-based stepwise regression and linear correlation analyses. The results showed that the following 5 parameters could be used to judge the nature of the cells, i.e. a) cytoplasmic area, b) cytoplasmic mean diameter, c) cytoplasmic form factor, d) nuclear form factor and e) N/C ratio. Comparing with cells of the other categories, values of the first 4 parameters for early cancer cells were decreased whereas that of the fifth parameter was significantly increased. From normal to hyperplastic and to dysplastic cells, the nuclear area and mean nuclear diameter were gradually increasing. Therefore, they were the major parameters in judging the degree of hyperplasia and dysplasia. These numerical features of morphologic quantitation conformed with the cytologic diagnostic criteria for cancer, hyperplasia and dysplasia under light microscope. It indicates that visual judgement is relatively accurate and application of the ocular micrometer to measure the cells would make this grading more objective.

  18. Looking for landmarks: the role of expert review and bibliometric analysis in evaluating scientific publication outputs.

    PubMed

    Allen, Liz; Jones, Ceri; Dolby, Kevin; Lynn, David; Walport, Mark

    2009-06-18

    To compare expert assessment with bibliometric indicators as tools to assess the quality and importance of scientific research papers. Shortly after their publication in 2005, the quality and importance of a cohort of nearly 700 Wellcome Trust (WT) associated research papers were assessed by expert reviewers; each paper was reviewed by two WT expert reviewers. After 3 years, we compared this initial assessment with other measures of paper impact. Shortly after publication, 62 (9%) of the 687 research papers were determined to describe at least a 'major addition to knowledge' -6 were thought to be 'landmark' papers. At an aggregate level, after 3 years, there was a strong positive association between expert assessment and impact as measured by number of citations and F1000 rating. However, there were some important exceptions indicating that bibliometric measures may not be sufficient in isolation as measures of research quality and importance, and especially not for assessing single papers or small groups of research publications. When attempting to assess the quality and importance of research papers, we found that sole reliance on bibliometric indicators would have led us to miss papers containing important results as judged by expert review. In particular, some papers that were highly rated by experts were not highly cited during the first three years after publication. Tools that link expert peer reviews of research paper quality and importance to more quantitative indicators, such as citation analysis would be valuable additions to the field of research assessment and evaluation.

  19. Facing Diversity of Science: A Challenge for Bibliometric Indicators

    ERIC Educational Resources Information Center

    Zitt, Michel

    2005-01-01

    Bibliometrics has come of age and is generally accepted, together with peer review, as one way to describe the activity of players in science. Appealing issues in bibliometrics include the characterization of a growth regime of research systems including the trade-offs of production-visibility; the measure of science-technology linkage and…

  20. An Economist's View on Bibliometrically Measuring Scientific Research

    ERIC Educational Resources Information Center

    Veugelers, Reinhilde

    2005-01-01

    Since the use of bibliometric instruments has grown and will continue to grow in the future, the quality, availability, and accessibility of data on publications and citations is of tantamount importance. But equally important is a correct use of the data. This means that an important task of the bibliometric field is to highlight not only what…

  1. An Economist's View on Bibliometrically Measuring Scientific Research

    ERIC Educational Resources Information Center

    Veugelers, Reinhilde

    2005-01-01

    Since the use of bibliometric instruments has grown and will continue to grow in the future, the quality, availability, and accessibility of data on publications and citations is of tantamount importance. But equally important is a correct use of the data. This means that an important task of the bibliometric field is to highlight not only what…

  2. Research Performance Evaluation: Some Critical Thoughts on Standard Bibliometric Indicators

    ERIC Educational Resources Information Center

    Anninos, Loukas N.

    2014-01-01

    The bibliometric methodology is an established technique for research evaluation as it offers an objective determination and comparison of research performance. This paper aims to critically assess some standard bibliometric indicators commonly used (based on publication and citation counts) to evaluate academic units, and examine whether there…

  3. Facing Diversity of Science: A Challenge for Bibliometric Indicators

    ERIC Educational Resources Information Center

    Zitt, Michel

    2005-01-01

    Bibliometrics has come of age and is generally accepted, together with peer review, as one way to describe the activity of players in science. Appealing issues in bibliometrics include the characterization of a growth regime of research systems including the trade-offs of production-visibility; the measure of science-technology linkage and…

  4. Publication Trends in Acupuncture Research: A 20-Year Bibliometric Analysis Based on PubMed

    PubMed Central

    Dong, Ming; Zhou, Kehua; Mita, Carol; Liu, Jianping; Wayne, Peter M.

    2016-01-01

    Objective Acupuncture has become popular and widely practiced in many countries around the world. Despite the large amount of acupuncture-related literature that has been published, broader trends in the prevalence and scope of acupuncture research remain underexplored. The current study quantitatively analyzes trends in acupuncture research publications in the past 20 years. Methods A bibliometric approach was used to search PubMed for all acupuncture-related research articles including clinical and animal studies. Inclusion criteria were articles published between 1995 and 2014 with sufficient information for bibliometric analyses. Rates and patterns of acupuncture publication within the 20 year observational period were estimated, and compared with broader publication rates in biomedicine. Identified eligible publications were further analyzed with respect to study type/design, clinical condition addressed, country of origin, and journal impact factor. Results A total of 13,320 acupuncture-related publications were identified using our search strategy and eligibility criteria. Regression analyses indicated an exponential growth in publications over the past two decades, with a mean annual growth rate of 10.7%. This compares to a mean annual growth rate of 4.5% in biomedicine. A striking trend was an observed increase in the proportion of randomized clinical trials (RCTs), from 7.4% in 1995 to 20.3% in 2014, exceeding the 4.5% proportional growth of RCTs in biomedicine. Over the 20 year period, pain was consistently the most common focus of acupuncture research (37.9% of publications). Other top rankings with respect to medical focus were arthritis, neoplasms/cancer, pregnancy or labor, mood disorders, stroke, nausea/vomiting, sleep, and paralysis/palsy. Acupuncture research was conducted in 60 countries, with the top 3 contributors being China (47.4%), United States (17.5%), and United Kingdom (8.2%). Retrieved articles were published mostly in complementary and

  5. Publication Trends in Acupuncture Research: A 20-Year Bibliometric Analysis Based on PubMed.

    PubMed

    Ma, Yan; Dong, Ming; Zhou, Kehua; Mita, Carol; Liu, Jianping; Wayne, Peter M

    2016-01-01

    Acupuncture has become popular and widely practiced in many countries around the world. Despite the large amount of acupuncture-related literature that has been published, broader trends in the prevalence and scope of acupuncture research remain underexplored. The current study quantitatively analyzes trends in acupuncture research publications in the past 20 years. A bibliometric approach was used to search PubMed for all acupuncture-related research articles including clinical and animal studies. Inclusion criteria were articles published between 1995 and 2014 with sufficient information for bibliometric analyses. Rates and patterns of acupuncture publication within the 20 year observational period were estimated, and compared with broader publication rates in biomedicine. Identified eligible publications were further analyzed with respect to study type/design, clinical condition addressed, country of origin, and journal impact factor. A total of 13,320 acupuncture-related publications were identified using our search strategy and eligibility criteria. Regression analyses indicated an exponential growth in publications over the past two decades, with a mean annual growth rate of 10.7%. This compares to a mean annual growth rate of 4.5% in biomedicine. A striking trend was an observed increase in the proportion of randomized clinical trials (RCTs), from 7.4% in 1995 to 20.3% in 2014, exceeding the 4.5% proportional growth of RCTs in biomedicine. Over the 20 year period, pain was consistently the most common focus of acupuncture research (37.9% of publications). Other top rankings with respect to medical focus were arthritis, neoplasms/cancer, pregnancy or labor, mood disorders, stroke, nausea/vomiting, sleep, and paralysis/palsy. Acupuncture research was conducted in 60 countries, with the top 3 contributors being China (47.4%), United States (17.5%), and United Kingdom (8.2%). Retrieved articles were published mostly in complementary and alternative medicine (CAM

  6. Association between bibliometric parameters, reporting and methodological quality of randomised controlled trials in vascular and endovascular surgery.

    PubMed

    Hajibandeh, Shahab; Hajibandeh, Shahin; Antoniou, George A; Green, Patrick A; Maden, Michelle; Torella, Francesco

    2017-04-01

    Purpose We aimed to investigate association between bibliometric parameters, reporting and methodological quality of vascular and endovascular surgery randomised controlled trials. Methods The most recent 75 and oldest 75 randomised controlled trials published in leading journals over a 10-year period were identified. The reporting quality was analysed using the CONSORT statement, and methodological quality with the Intercollegiate Guidelines Network checklist. We used exploratory univariate and multivariable linear regression analysis to investigate associations. Findings Bibliometric parameters such as type of journal, study design reported in title, number of pages; external funding, industry sponsoring and number of citations are associated with reporting quality. Moreover, parameters such as type of journal, subject area and study design reported in title are associated with methodological quality. Conclusions The bibliometric parameters of randomised controlled trials may be independent predictors for their reporting and methodological quality. Moreover, the reporting quality of randomised controlled trials is associated with their methodological quality and vice versa.

  7. Software survey: VOSviewer, a computer program for bibliometric mapping.

    PubMed

    van Eck, Nees Jan; Waltman, Ludo

    2010-08-01

    We present VOSviewer, a freely available computer program that we have developed for constructing and viewing bibliometric maps. Unlike most computer programs that are used for bibliometric mapping, VOSviewer pays special attention to the graphical representation of bibliometric maps. The functionality of VOSviewer is especially useful for displaying large bibliometric maps in an easy-to-interpret way. The paper consists of three parts. In the first part, an overview of VOSviewer's functionality for displaying bibliometric maps is provided. In the second part, the technical implementation of specific parts of the program is discussed. Finally, in the third part, VOSviewer's ability to handle large maps is demonstrated by using the program to construct and display a co-citation map of 5,000 major scientific journals.

  8. Software survey: VOSviewer, a computer program for bibliometric mapping

    PubMed Central

    Waltman, Ludo

    2009-01-01

    We present VOSviewer, a freely available computer program that we have developed for constructing and viewing bibliometric maps. Unlike most computer programs that are used for bibliometric mapping, VOSviewer pays special attention to the graphical representation of bibliometric maps. The functionality of VOSviewer is especially useful for displaying large bibliometric maps in an easy-to-interpret way. The paper consists of three parts. In the first part, an overview of VOSviewer’s functionality for displaying bibliometric maps is provided. In the second part, the technical implementation of specific parts of the program is discussed. Finally, in the third part, VOSviewer’s ability to handle large maps is demonstrated by using the program to construct and display a co-citation map of 5,000 major scientific journals. PMID:20585380

  9. The Mozart Effect: A quantitative EEG study.

    PubMed

    Verrusio, Walter; Ettorre, Evaristo; Vicenzini, Edoardo; Vanacore, Nicola; Cacciafesta, Mauro; Mecarelli, Oriano

    2015-09-01

    The aim of this study is to investigate the influence of Mozart's music on brain activity through spectral analysis of the EEG in young healthy adults (Adults), in healthy elderly (Elderly) and in elderly with Mild Cognitive Impairment (MCI). EEG recording was performed at basal rest conditions and after listening to Mozart's K448 or "Fur Elise" Beethoven's sonatas. After listening to Mozart, an increase of alpha band and median frequency index of background alpha rhythm activity (a pattern of brain wave activity linked to memory, cognition and open mind to problem solving) was observed both in Adults and in Elderly. No changes were observed in MCI. After listening to Beethoven, no changes in EEG activity were detected. This results may be representative of the fact that said Mozart's music is able to "activate" neuronal cortical circuits related to attentive and cognitive functions. Copyright © 2015 Elsevier Inc. All rights reserved.

  10. Quantitative studies of ribosome conformational dynamics.

    PubMed

    Fraser, Christopher S; Doudna, Jennifer A

    2007-05-01

    The ribosome is a dynamic machine that undergoes many conformational rearrangements during the initiation of protein synthesis. Significant differences exist between the process of protein synthesis initiation in eubacteria and eukaryotes. In particular, the initiation of eukaryotic protein synthesis requires roughly an order of magnitude more initiation factors to promote efficient mRNA recruitment and ribosomal recognition of the start codon than are needed for eubacterial initiation. The mechanisms by which these initiation factors promote ribosome conformational changes during stages of initiation have been studied using cross-linking, footprinting, site-directed probing, cryo-electron microscopy, X-ray crystallography, fluorescence spectroscopy and single-molecule techniques. Here, we review how the results of these different approaches have begun to converge to yield a detailed molecular understanding of the dynamic motions that the eukaryotic ribosome cycles through during the initiation of protein synthesis.

  11. Transparency in Europe: A Quantitative Study.

    PubMed

    Bouder, Frederic; Way, Dominic; Löfstedt, Ragnar; Evensen, Darrick

    2015-07-01

    In recent years, European pharmaceutical regulators have increasingly committed to heightening access to raw safety-related data as part of a wave of transparency initiatives (e.g., providing public Internet-mediated access to clinical trials data). Yet, the regulators--who are under significant pressure--have not yet benefited from a systematic review of this new policy. In seeking to inject much needed evidence, this article explores the effects of new transparency policies designed to promote meaningful communication of risks and benefits to patients. Results of a cross-national European survey with respondents from Great Britain, the Netherlands, Spain, France, Germany, and Sweden (N = 5,648) shed light on how patients and the public are likely to react to the regulators' new transparency policies. The findings demonstrate clear national variations in how European citizens are likely to react and emphasize the need to develop evidence-based, reasoned transparency policies that integrate benefit-risk communication. The authors conclude by providing six specific recommendations, informed by the study, that seek to improve the European transparency model both within the medical field and across health, safety, and environmental policy domains. © 2015 Society for Risk Analysis.

  12. Research Review: Quantitative Magazine Studies, 1983-1993.

    ERIC Educational Resources Information Center

    Popovich, Mark N.

    1994-01-01

    Examines quantitative magazine research studies published in various journals during the period 1983-1993. Questions the heavy reliance on content analysis techniques to study the role of magazines in American society. Calls for a redirection in magazine research, combining media content studies with media effects studies. (SR)

  13. Research Review: Quantitative Magazine Studies, 1983-1993.

    ERIC Educational Resources Information Center

    Popovich, Mark N.

    1994-01-01

    Examines quantitative magazine research studies published in various journals during the period 1983-1993. Questions the heavy reliance on content analysis techniques to study the role of magazines in American society. Calls for a redirection in magazine research, combining media content studies with media effects studies. (SR)

  14. The APOSTEL recommendations for reporting quantitative optical coherence tomography studies.

    PubMed

    Cruz-Herranz, Andrés; Balk, Lisanne J; Oberwahrenbrock, Timm; Saidha, Shiv; Martinez-Lapiscina, Elena H; Lagreze, Wolf A; Schuman, Joel S; Villoslada, Pablo; Calabresi, Peter; Balcer, Laura; Petzold, Axel; Green, Ari J; Paul, Friedemann; Brandt, Alexander U; Albrecht, Philipp

    2016-06-14

    To develop consensus recommendations for reporting of quantitative optical coherence tomography (OCT) study results. A panel of experienced OCT researchers (including 11 neurologists, 2 ophthalmologists, and 2 neuroscientists) discussed requirements for performing and reporting quantitative analyses of retinal morphology and developed a list of initial recommendations based on experience and previous studies. The list of recommendations was subsequently revised during several meetings of the coordinating group. We provide a 9-point checklist encompassing aspects deemed relevant when reporting quantitative OCT studies. The areas covered are study protocol, acquisition device, acquisition settings, scanning protocol, funduscopic imaging, postacquisition data selection, postacquisition data analysis, recommended nomenclature, and statistical analysis. The Advised Protocol for OCT Study Terminology and Elements recommendations include core items to standardize and improve quality of reporting in quantitative OCT studies. The recommendations will make reporting of quantitative OCT studies more consistent and in line with existing standards for reporting research in other biomedical areas. The recommendations originated from expert consensus and thus represent Class IV evidence. They will need to be regularly adjusted according to new insights and practices. © 2016 American Academy of Neurology.

  15. The APOSTEL recommendations for reporting quantitative optical coherence tomography studies

    PubMed Central

    Cruz-Herranz, Andrés; Balk, Lisanne J.; Oberwahrenbrock, Timm; Saidha, Shiv; Martinez-Lapiscina, Elena H.; Lagreze, Wolf A.; Schuman, Joel S.; Villoslada, Pablo; Calabresi, Peter; Balcer, Laura; Petzold, Axel; Green, Ari J.; Paul, Friedemann; Brandt, Alexander U.

    2016-01-01

    Objective: To develop consensus recommendations for reporting of quantitative optical coherence tomography (OCT) study results. Methods: A panel of experienced OCT researchers (including 11 neurologists, 2 ophthalmologists, and 2 neuroscientists) discussed requirements for performing and reporting quantitative analyses of retinal morphology and developed a list of initial recommendations based on experience and previous studies. The list of recommendations was subsequently revised during several meetings of the coordinating group. Results: We provide a 9-point checklist encompassing aspects deemed relevant when reporting quantitative OCT studies. The areas covered are study protocol, acquisition device, acquisition settings, scanning protocol, funduscopic imaging, postacquisition data selection, postacquisition data analysis, recommended nomenclature, and statistical analysis. Conclusions: The Advised Protocol for OCT Study Terminology and Elements recommendations include core items to standardize and improve quality of reporting in quantitative OCT studies. The recommendations will make reporting of quantitative OCT studies more consistent and in line with existing standards for reporting research in other biomedical areas. The recommendations originated from expert consensus and thus represent Class IV evidence. They will need to be regularly adjusted according to new insights and practices. PMID:27225223

  16. Quantitative studies of immunofluorescent staining. VII. Quantitative reference standard slide for standardization of fluorescence microscopes.

    PubMed

    Rostami, R; Beutner, E H; Kumar, V

    1992-01-01

    We evaluated a quantitative reference standard (QRS) slide with 10-microns beads with different concentrations of Coulter Electronics green dye No. 1. Microfluorospectrophotometric readings of the QRS slides provided quantitative comparisons between the sensitivity of the different fluorescence microscopes. The visual comparisons between beads with a range of intensities of fluorescence of Coulter Electronics green dye No. 1 indicated that the end points vary with different optical systems as do the end points in standard indirect immunofluorescent titrations. Fluorescent emission wavelength of QRS slide beads gave the same peak as fluorescein-labeled beads; both differed from the peak of orange beads of an 'Optical Standard' slide. Since shelf life studies show no changes in fluorescence intensity of beads over a period of 27 months or longer, QRS slide beads can afford a device for standardization of fluorescence microscopes used for immunofluorescent tests.

  17. Bibliometric analysis of literature on female genital mutilation: (1930 - 2015).

    PubMed

    Sweileh, Waleed M

    2016-10-10

    Female genital mutilation/cutting (FGM/C) is a common harmful traditional practice in many communities in Africa and to a lesser extent in Middle East and other regions in the world. In order to better understand publishing on this topic, we conducted a bibliometric study on FGM/C. Bibliometric analyses can be used as an indicator of the extent of interaction of researchers, health authorities, and communities with a particular health issue. Scopus database was used to retrieve data on FGM/C. Keywords used were "female genital mutilation", "female genital circumcision", "female genital cutting" and "female circumcision". Specifically, the number of publications, top productive countries and institutions, highly cited articles, citation analysis, co-authorships, international collaboration, role of African countries, top active authors, and journals involved in publishing articles on FGM/C were reviewed and analyzed. We indirectly assessed the impact of publications using total number of citations received, average number of citations per article, Hirsch-index, percentage of highly cited articles, and journal's impact factor. One thousand and thirty-five publications on FGM/C were retrieved. The h-index of retrieved articles was 37. A steep rise in number of publications was noticed in mid-1990s and again in 2012. More than half of retrieved articles were published from 2006 - 2015. A total of 65 countries contributed. The top ten productive countries included ones from Northern America, Europe and Africa. Nigeria and Egypt were the most active African countries in FGM/C publications. At least nine African academic institutions were actively involved on FGM/C publications. Articles on FGM/C that received the highest number of citations were those that focused on negative physical and psychosexual consequences of FGM/C. Journal topic areas were obstetrics/gynecology, public health, and psychological sociology. Collaboration between African and European countries on

  18. Microfluidics for High-Throughput Quantitative Studies of Early Development.

    PubMed

    Levario, Thomas J; Lim, Bomyi; Shvartsman, Stanislav Y; Lu, Hang

    2016-07-11

    Developmental biology has traditionally relied on qualitative analyses; recently, however, as in other fields of biology, researchers have become increasingly interested in acquiring quantitative knowledge about embryogenesis. Advances in fluorescence microscopy are enabling high-content imaging in live specimens. At the same time, microfluidics and automation technologies are increasing experimental throughput for studies of multicellular models of development. Furthermore, computer vision methods for processing and analyzing bioimage data are now leading the way toward quantitative biology. Here, we review advances in the areas of fluorescence microscopy, microfluidics, and data analysis that are instrumental to performing high-content, high-throughput studies in biology and specifically in development. We discuss a case study of how these techniques have allowed quantitative analysis and modeling of pattern formation in the Drosophila embryo.

  19. What Effect Does Self-Citation Have on Bibliometric Measures in Academic Plastic Surgery?

    PubMed

    Swanson, Edward W; Miller, Devin T; Susarla, Srinivas M; Lopez, Joseph; Lough, Denver M; May, James W; Redett, Richard J

    2016-09-01

    Research productivity plays a significant role in academic promotions. Currently, various bibliometric measures utilizing citation counts are used to judge an author's work. With increasing numbers of journals, numbers of open access publications, ease of online submission, and expedited indexing of accepted manuscripts, it is plausible that an author could influence his/her own bibliometric measures through self-citation. The purpose of this study was to determine the impact of self-citation in academic plastic surgery. A cohort of full-time academic plastic surgeons was identified from 9 U.S. plastic surgery training programs. For all included faculty, academic rank was retrieved from department/division websites, and bibliometric measures were assessed using a subscription bibliographic citation database (Scopus, Reed Elsevier, London, UK). Bibliometric measures included the Hirsch index (h-index, the number of publications h which are cited ≥ h times), total number of publications, and total number of citations. The h-index and total number of citations were collected with and without self-citations. Percent changes in the h-index and total citations were calculated after removal of self-citations and compared across academic ranks and levels of research productivity (total publications, h-index, and total citations). The study cohort consisted of 169 full-time academic plastic surgeons. The h-index and total citations experienced decreases of 2.8 ± 5.0% (P < 0.0001) and 4.5 ± 4.6% (P < 0.0001), respectively, after correction for self-citation. More than half of the cohort (n = 113, 67%) did not experience a change in the h-index after removal of self-citations. These decreases did not vary across academic rank. Surgeons who self-cited at rates greater than 5% were 9.8 times more likely (95% confidence interval, 4.5-21.9; P < 0.001) to have their h-index change as a result of self-citation (after adjusting for academic rank). There were weak correlations

  20. A bibliometric analysis of the citation classics of acute appendicitis.

    PubMed

    Varzgalis, Manvydas; Bowden, Dermot J; Mc Donald, Ciaran K; Kerin, Michael J

    2017-07-01

    Acute appendicitis is one of the most commonly encountered emergency surgical conditions. An understanding of the most highly cited research works in this field is key to good evidence based clinical practice. To perform a bibliometric analysis on the 100 most frequently cited articles in the field of acute appendicitis. The database of the Institute for Scientific Information (ISI) Web of Science Expanded citation index was searched to identify the 100 most frequently cited articles in the field of acute appendicitis. The web of science expanded citation index tracks article citations made since 1946. The top 100 most frequently cited articles were selected for analysis in this series. The most frequently cited article was cited 649 times and the least cited three article 93 times. The average number of citations per article was 167.74. The top 100 cited articles originated from 17 countries. Over half of the papers originated from the USA. Fifty-one of the papers concentrated on diagnostics of acute appendicitis. Thirty-six papers looked at the treatment of acute appendicitis with 30 of these dealing with the surgical management of the disease. There were 6 studies at level 1a, 20 studies at level 1b and 43,5,17 and 9 studies at levels 2, 3, 4 and 5 respectively. Bibliometric analysis of the citation classics in a given field can provide interesting insights into the relationship between the quality of research outputs and clinical practice. The study of acute appendicitis remains an active field of research with a growing body of higher quality evidence underpinning our clinical practice.

  1. Research on health inequalities: A bibliometric analysis (1966-2014).

    PubMed

    Bouchard, Louise; Albertini, Marcelo; Batista, Ricardo; de Montigny, Joanne

    2015-09-01

    The objective of this study is to report on research production and publications on health inequalities through a bibliometric analysis covering publications from 1966 to 2014 and a content analysis of the 25 most-cited papers. A database of 49,294 references was compiled from the search engine Web of Science. The first article appears in 1966 and deals with equality and civil rights in the United States and the elimination of racial discrimination in access to medical care. By 2003, the term disparity has gained in prominence relative to the term inequality which was initially elected by the researchers. Marmot's 1991 article is one of the five papers with the largest number of citations and contributes to the central perspective of social determinants of health and the British influence on the international status of research on social inequalities of health.

  2. PubChem applications in drug discovery: a bibliometric analysis.

    PubMed

    Cheng, Tiejun; Pan, Yongmei; Hao, Ming; Wang, Yanli; Bryant, Stephen H

    2014-11-01

    A bibliometric analysis of PubChem applications is presented by reviewing 1132 research articles. The massive volume of chemical structure and bioactivity data in PubChem and its online services have been used globally in various fields including chemical biology, medicinal chemistry and informatics research. PubChem supports drug discovery in many aspects such as lead identification and optimization, compound-target profiling, polypharmacology studies and unknown chemical identity elucidation. PubChem has also become a valuable resource for developing secondary databases, informatics tools and web services. The growing PubChem resource with its public availability offers support and great opportunities for the interrogation of pharmacological mechanisms and the genetic basis of diseases, which are vital for drug innovation and repurposing.

  3. PubChem applications in drug discovery: a bibliometric analysis

    PubMed Central

    Cheng, Tiejun; Pan, Yongmei; Hao, Ming; Wang, Yanli; Bryant, Stephen H.

    2014-01-01

    A bibliometric analysis of PubChem applications is presented by reviewing 1132 research articles. The massive volume of chemical structure and bioactivity data in PubChem and its online services has been used globally in various fields including chemical biology, medicinal chemistry and informatics research. PubChem supports drug discovery in many aspects such as lead identification and optimization, compound–target profiling, polypharmacology studies and unknown chemical identity elucidation. PubChem has also become a valuable resource for developing secondary databases, informatics tools and web services. The growing PubChem resource with its public availability offers support and great opportunities for the interrogation of pharmacological mechanisms and the genetic basis of diseases, which are vital for drug innovation and repurposing. PMID:25168772

  4. Quantitative proteomics to study carbapenem resistance in Acinetobacter baumannii

    PubMed Central

    Tiwari, Vishvanath; Tiwari, Monalisa

    2014-01-01

    Acinetobacter baumannii is an opportunistic pathogen causing pneumonia, respiratory infections and urinary tract infections. The prevalence of this lethal pathogen increases gradually in the clinical setup where it can grow on artificial surfaces, utilize ethanol as a carbon source. Moreover it resists desiccation. Carbapenems, a β-lactam, are the most commonly prescribed drugs against A. baumannii. Resistance against carbapenem has emerged in Acinetobacter baumannii which can create significant health problems and is responsible for high morbidity and mortality. With the development of quantitative proteomics, a considerable progress has been made in the study of carbapenem resistance of Acinetobacter baumannii. Recent updates showed that quantitative proteomics has now emerged as an important tool to understand the carbapenem resistance mechanism in Acinetobacter baumannii. Present review also highlights the complementary nature of different quantitative proteomic methods used to study carbapenem resistance and suggests to combine multiple proteomic methods for understanding the response to antibiotics by Acinetobacter baumannii. PMID:25309531

  5. Returning to Work after Cancer: Quantitative Studies and Prototypical Narratives

    PubMed Central

    Steiner, John F.; Nowels, Carolyn T.; Main, Deborah S.

    2009-01-01

    Objective A combination of quantitative data and illustrative narratives may allow cancer survivorship researchers to disseminate their research findings more broadly. We identified recent, methodologically rigorous quantitative studies on return to work after cancer, summarized the themes from these studies, and illustrated those themes with narratives of individual cancer survivors. Methods We reviewed English-language studies of return to work for adult cancer survivors through June, 2008, and identified 13 general themes from papers that met methodological criteria (population-based sampling, prospective and longitudinal assessment, detailed assessment of work, evaluation of economic impact, assessment of moderators of work return, and large sample size). We drew survivorship narratives from a prior qualitative research study to illustrate these themes. Results Nine quantitative studies met 4 or more of our 6 methodological criteria. These studies suggested that most cancer survivors could return to work without residual disabilities. Cancer site, clinical prognosis, treatment modalities, socioeconomic status, and attributes of the job itself influenced the likelihood of work return. Three narratives - a typical survivor who returned to work after treatment, an individual unable to return to work, and an inspiring survivor who returned to work despite substantial barriers - illustrated many of the themes from the quantitative literature while providing additional contextual details. Conclusion Illustrative narratives can complement the findings of cancer survivorship research if researchers are rigorous and transparent in the selection, analysis, and retelling of those stories. PMID:19507264

  6. Music and Affective Phenomena: A 20-Year Content and Bibliometric Analysis of Research in Three Eminent Journals

    ERIC Educational Resources Information Center

    Diaz, Frank M.; Silveira, Jason M.

    2014-01-01

    The purpose of this study was to establish trends in the study of music and affective phenomena through a content and bibliometric analysis of three eminent music research journals, the "Journal of Research in Music Education", "Psychology of Music", and "Music Perception", for the years 1990 through 2009. Excluding…

  7. Music and Affective Phenomena: A 20-Year Content and Bibliometric Analysis of Research in Three Eminent Journals

    ERIC Educational Resources Information Center

    Diaz, Frank M.; Silveira, Jason M.

    2014-01-01

    The purpose of this study was to establish trends in the study of music and affective phenomena through a content and bibliometric analysis of three eminent music research journals, the "Journal of Research in Music Education", "Psychology of Music", and "Music Perception", for the years 1990 through 2009. Excluding…

  8. Integrated care: a comprehensive bibliometric analysis and literature review.

    PubMed

    Sun, Xiaowei; Tang, Wenxi; Ye, Ting; Zhang, Yan; Wen, Bo; Zhang, Liang

    2014-04-01

    Integrated care could not only fix up fragmented health care but also improve the continuity of care and the quality of life. Despite the volume and variety of publications, little is known about how 'integrated care' has developed. There is a need for a systematic bibliometric analysis on studying the important features of the integrated care literature. To investigate the growth pattern, core journals and jurisdictions and identify the key research domains of integrated care. We searched Medline/PubMed using the search strategy '(delivery of health care, integrated [MeSH Terms]) OR integrated care [Title/Abstract]' without time and language limits. Second, we extracted the publishing year, journals, jurisdictions and keywords of the retrieved articles. Finally, descriptive statistical analysis by the Bibliographic Item Co-occurrence Matrix Builder and hierarchical clustering by SPSS were used. As many as 9090 articles were retrieved. Results included: (1) the cumulative numbers of the publications on integrated care rose perpendicularly after 1993; (2) all documents were recorded by 1646 kinds of journals. There were 28 core journals; (3) the USA is the predominant publishing country; and (4) there are six key domains including: the definition/models of integrated care, interdisciplinary patient care team, disease management for chronically ill patients, types of health care organizations and policy, information system integration and legislation/jurisprudence. Integrated care literature has been most evident in developed countries. International Journal of Integrated Care is highly recommended in this research area. The bibliometric analysis and identification of publication hotspots provides researchers and practitioners with core target journals, as well as an overview of the field for further research in integrated care.

  9. Integrated care: a comprehensive bibliometric analysis and literature review

    PubMed Central

    Sun, Xiaowei; Tang, Wenxi; Ye, Ting; Zhang, Yan; Wen, Bo; Zhang, Liang

    2014-01-01

    Introduction Integrated care could not only fix up fragmented health care but also improve the continuity of care and the quality of life. Despite the volume and variety of publications, little is known about how ‘integrated care’ has developed. There is a need for a systematic bibliometric analysis on studying the important features of the integrated care literature. Aim To investigate the growth pattern, core journals and jurisdictions and identify the key research domains of integrated care. Methods We searched Medline/PubMed using the search strategy ‘(delivery of health care, integrated [MeSH Terms]) OR integrated care [Title/Abstract]’ without time and language limits. Second, we extracted the publishing year, journals, jurisdictions and keywords of the retrieved articles. Finally, descriptive statistical analysis by the Bibliographic Item Co-occurrence Matrix Builder and hierarchical clustering by SPSS were used. Results As many as 9090 articles were retrieved. Results included: (1) the cumulative numbers of the publications on integrated care rose perpendicularly after 1993; (2) all documents were recorded by 1646 kinds of journals. There were 28 core journals; (3) the USA is the predominant publishing country; and (4) there are six key domains including: the definition/models of integrated care, interdisciplinary patient care team, disease management for chronically ill patients, types of health care organizations and policy, information system integration and legislation/jurisprudence. Discussion and conclusion Integrated care literature has been most evident in developed countries. International Journal of Integrated Care is highly recommended in this research area. The bibliometric analysis and identification of publication hotspots provides researchers and practitioners with core target journals, as well as an overview of the field for further research in integrated care. PMID:24987322

  10. Metamorphism of eucrite meteorites studied quantitatively using induced thermoluminescence

    NASA Technical Reports Server (NTRS)

    Batchelor, J. David; Sears, Derek W. G.

    1991-01-01

    Induced thermoluminescence studies provide a new and quantitative means of determining relative metamorphic intensities for eucrite meteorites, the simplest and most ancient products of basaltic volcanism. Using this technique, it is shown that the eucrites constitute a continuous metamorphic series and not, as commonly assumed, two groups of metamorphosed and nonmetamorphosed meteorites. It is suggested that the method may have applications to other basalts.

  11. A Quantitative Study of High School Yearbook Content.

    ERIC Educational Resources Information Center

    Krepel, Wayne J.; DuVall, Charles R.

    The purpose of this study was to analyze high school yearbooks, relative to quantitative page allotments, when classified by the size of the community, the type of socioeconomic environment of the school, and the size of the graduating class. A normative survey was conducted using a questionnaire requesting the respondent to furnish a copy of the…

  12. Simulation and the Development of Clinical Judgment: A Quantitative Study

    ERIC Educational Resources Information Center

    Holland, Susan

    2015-01-01

    The purpose of this quantitative pretest posttest quasi-experimental research study was to explore the effect of the NESD on clinical judgment in associate degree nursing students and compare the differences between groups when the Nursing Education Simulation Design (NESD) guided simulation in order to identify educational strategies promoting…

  13. Metamorphism of eucrite meteorites studied quantitatively using induced thermoluminescence

    NASA Technical Reports Server (NTRS)

    Batchelor, J. David; Sears, Derek W. G.

    1991-01-01

    Induced thermoluminescence studies provide a new and quantitative means of determining relative metamorphic intensities for eucrite meteorites, the simplest and most ancient products of basaltic volcanism. Using this technique, it is shown that the eucrites constitute a continuous metamorphic series and not, as commonly assumed, two groups of metamorphosed and nonmetamorphosed meteorites. It is suggested that the method may have applications to other basalts.

  14. Simulation and the Development of Clinical Judgment: A Quantitative Study

    ERIC Educational Resources Information Center

    Holland, Susan

    2015-01-01

    The purpose of this quantitative pretest posttest quasi-experimental research study was to explore the effect of the NESD on clinical judgment in associate degree nursing students and compare the differences between groups when the Nursing Education Simulation Design (NESD) guided simulation in order to identify educational strategies promoting…

  15. Bibliometric trends in ophthalmology 1997-2009

    PubMed Central

    Mansour, Ahmad M; Mollayess, Georges El; Habib, Robert; Arabi, Asma; Medawar, Walid A

    2015-01-01

    Aims: To track citation patterns in ophthalmic journals and contrast them with major medical and surgical journals from 1997 to 2009. In addition, we want to familiarize the ophthalmic community with bibliometrics indices. Materials and Methods: Data retrieved from Institute for Scientific Information and related websites include 2-year journal impact factor JIF, 5-year impact, Eigenfactor score, H-factor, Article Influence score, and SCImago factor. Results: JIF rose steadily around 10% annually in ophthalmic journals, and likewise for major medical and surgical journals. JIF correlated with recent bibliometric indicators like 5-year impact, H index, and SCImago factor but not with Eigenfactor. Ophthalmic journals publishing reviews, basic science, or large volume on broad range of topics ranked at the top for JIF, while subspecialty journals tended to have low JIF. JIF of subspecialty journal Retina rose from 0.740 (rank 23) in 2000 to 3.088 in 2007 (rank 6). Conclusions: JIF tends to rise annually by 10% in medical, surgical, and ophthalmic fields. Journals publishing reviews, basic science, or large volume on broad range of topics rank at the top for JIF. The rapid rise of JIF for Retina unlike other subspecialties that stayed status quo is multifactorial: Change in editorial policies (introduction of review articles and omission of case reports) and technological advances in the retinal field. PMID:25686064

  16. Bibliometric trends in ophthalmology 1997-2009.

    PubMed

    Mansour, Ahmad M; Mollayess, Georges E L; Habib, Robert; Arabi, Asma; Medawar, Walid A

    2015-01-01

    To track citation patterns in ophthalmic journals and contrast them with major medical and surgical journals from 1997 to 2009. In addition, we want to familiarize the ophthalmic community with bibliometrics indices. Data retrieved from Institute for Scientific Information and related websites include 2-year journal impact factor JIF, 5-year impact, Eigenfactor score, H-factor, Article Influence score, and SCImago factor. JIF rose steadily around 10% annually in ophthalmic journals, and likewise for major medical and surgical journals. JIF correlated with recent bibliometric indicators like 5-year impact, H index, and SCImago factor but not with Eigenfactor. Ophthalmic journals publishing reviews, basic science, or large volume on broad range of topics ranked at the top for JIF, while subspecialty journals tended to have low JIF. JIF of subspecialty journal Retina rose from 0.740 (rank 23) in 2000 to 3.088 in 2007 (rank 6). JIF tends to rise annually by 10% in medical, surgical, and ophthalmic fields. Journals publishing reviews, basic science, or large volume on broad range of topics rank at the top for JIF. The rapid rise of JIF for Retina unlike other subspecialties that stayed status quo is multifactorial: Change in editorial policies (introduction of review articles and omission of case reports) and technological advances in the retinal field.

  17. Mapping the scientific research on atypical antipsychotic drugs in Spain: a bibliometric assessment.

    PubMed

    López-Muñoz, Francisco; Rubio, Gabriel; Molina, Juan D; Shen, Winston W; Pérez-Nieto, Miguel A; Moreno, Raquel; Huelves, Lorena; Noriega, Concha; García-García, Pilar; Alamo, Cecilio

    2013-01-01

    We carried out a bibliometric study on the scientific publications in relation to atypical antipsychotic drugs (AADs) in Spain. We used the EMBASE and MEDLINE databases and we applied some bibliometric indicators of paper production and dispersion (Price's law and Bradford's law, respectively). We also calculated the participation index of the different countries and correlated the bibliometric data with some social and health data (total per capita expenditure on health and gross domestic expenditure on research and development). We collected 656 original papers published between 1988 and 2011. Our study results fulfilled Price's law with scientific production on AADs showing exponential growth (correlation coefficient r = 0.9693, vs. r = 0.9177 after linear adjustment). The most widely studied drugs were risperidone (181 papers), olanzapine (143), clozapine (94), and quetiapine (74). Division into Bradford zones yielded a nucleus occupied by the European Psychiatry and European Neuropsychopharmacology (70 articles). Totally 194 different journals were published, with 5 of the first 10 used journals having an impact factor being greater than 4. The publications on AADs in Spain have undergone exponential growth over the studied period, without evidence of reaching a saturation point.

  18. Why Include Bibliometric Analysis in the Activities of a Library Specialized in Astronomy? — Notes From the Libraries of INTA

    NASA Astrophysics Data System (ADS)

    Alonso-Valdivielso, M. Á.; Antonio, E. G.

    2010-10-01

    We describe the different possibilities that several bibliometric studies offer the National Institute of Aerospace Technology (INTA) and the Center for Astrobiology (CAB) libraries. The main object in this paper is to show how the results of these investigations are useful for various matters, such as preservation options, exploitation and diffusion of these results, and facilitating internal information management.

  19. NASA Aeronautics and Space Database for bibliometric analysis

    NASA Technical Reports Server (NTRS)

    Powers, R.; Rudman, R.

    2004-01-01

    The authors use the NASA Aeronautics and Space Database to perform bibliometric analysis of citations. This paper explains their research methodology and gives some sample results showing collaboration trends between NASA Centers and other institutions.

  20. On the Classification of the Classical Bibliometric Laws.

    ERIC Educational Resources Information Center

    Egghe, L.

    1988-01-01

    Reviews the bibliometric laws of Bradford, Leimkuhler, Mandelbrot, Lotka, Brookes, and Zipf, and classifies them in two groups, based on the use of mathematical logic and equivalency. (8 references) (CLB)

  1. A longitudinal analysis of bibliometric and impact factor trends among the core international journals of nursing, 1977-2008.

    PubMed

    Smith, Derek R

    2010-12-01

    Although bibliometric analysis affords significant insight into the progression and distribution of information within a particular research field, detailed longitudinal studies of this type are rare within the field of nursing. This study aimed to investigate, from a bibliometric perspective, the progression and trends of core international nursing journals over the longest possible time period. A detailed bibliometric analysis was undertaken among 7 core international nursing periodicals using custom historical data sourced from the Thomson Reuters Journal Citation Reports®. In the 32 years between 1977 and 2008, the number of citations received by these 7 journals increased over 700%. A sustained and statistically significant (p<0.001) 3-fold increase was also observed in the average impact factor score during this period. Statistical analysis revealed that all periodicals experienced significant (p<0.001) improvements in their impact factors over time, with gains ranging from approximately 2- to 78-fold. Overall, this study provides one of the most comprehensive, longitudinal bibliometric analyses ever conducted in the field of nursing. Impressive and continual impact factor gains suggest that published nursing research is being increasingly seen, heard and cited in the international academic community. Copyright © 2010 Elsevier Ltd. All rights reserved.

  2. Bibliometric analysis of theses and dissertations on prematurity in the Capes database.

    PubMed

    Pizzani, Luciana; Lopes, Juliana de Fátima; Manzini, Mariana Gurian; Martinez, Claudia Maria Simões

    2012-01-01

    To perform a bibliometric analysis of theses and dissertations on prematurity in the Capes database from 1987 to 2009. This is a descriptive study that used the bibliometric approach for the production of indicators of scientific production. Operationally, the methodology was developed in four steps: 1) construction of the theoretical framework; 2) data collection sourced from the abstracts of theses and dissertations available in the Capes Thesis Database which presented the issue of prematurity in the period 1987 to 2009; 3) organization, processing and construction of bibliometric indicators; 4) analysis and interpretation of results. Increase in the scientific literature on prematurity during the period 1987 to 2009; production is represented mostly by dissertations; the institution that received prominence was the Universidade de São Paulo. The studies are directed toward the low birth weight and very low birth weight preterm newborn, encompassing the social, biological and multifactorial causes of prematurity. There is a qualified, diverse and substantial scientific literature on prematurity developed in various graduate programs of higher education institutions in Brazil.

  3. Characterizing scientific production of Italian Oral Surgery professionals through evaluation of bibliometric indices

    PubMed Central

    Tetè, Stefano; Zizzari, Vincenzo Luca; De Carlo, Alessandro; Lorusso, Felice; Di Nicola, Marta; Piattelli, Adriano; Gherlone, Enrico; Polimeni, Antonella

    2014-01-01

    Summary The aim of this study was to characterize the scientific production of Italian Oral Surgery professionals by evaluating different bibliometric indices. The bibliometric evaluation was conducted on the Scopus Database upon all the Active Members joining three important Italian scientific societies in Oral Surgery (SIdCO, SIO, and SICOI). The scientific production was analysed by considering the number of total publications, number of total citations, h-index, and hc-index. Moreover, the overall sample was divided into two groups (Academics and Not Academics), according to the fact the professionals had or not a university position, and then into sub-groups according to the different career lengths. Statistical analyses were performed to compare the scientific productivity amongst groups. For all the considered parameters a lack of homogeneity between groups was reported, and significantly greater mean values were recorded for the Academics compared to the Not Academics Group. Moreover, the h-index values increased more regularly as the career length progressed than the hc-index values, even if the last seemed to be less variable. h- and hc-indices are both stable bibliometric parameters, but as the hc-index values are related not only to the number of citation but also to their age, it seems to be less influenced by the authors’ career length. Bibliometric analysis of the scientific production in dentistry may facilitate the recognition of factors that may further enhance research activity and clinical performance and be useful for a comparative assessment of authors or research groups in terms of quality and quantity of the scientific production. PMID:24753798

  4. Characterizing scientific production of Italian Oral Surgery professionals through evaluation of bibliometric indices.

    PubMed

    Tetè, Stefano; Zizzari, Vincenzo Luca; De Carlo, Alessandro; Lorusso, Felice; Di Nicola, Marta; Piattelli, Adriano; Gherlone, Enrico; Polimeni, Antonella

    2014-01-01

    The aim of this study was to characterize the scientific production of Italian Oral Surgery professionals by evaluating different bibliometric indices. The bibliometric evaluation was conducted on the Scopus Database upon all the Active Members joining three important Italian scientific societies in Oral Surgery (SIdCO, SIO, and SICOI). The scientific production was analysed by considering the number of total publications, number of total citations, h-index, and hc-index. Moreover, the overall sample was divided into two groups (Academics and Not Academics), according to the fact the professionals had or not a university position, and then into sub-groups according to the different career lengths. Statistical analyses were performed to compare the scientific productivity amongst groups. For all the considered parameters a lack of homogeneity between groups was reported, and significantly greater mean values were recorded for the Academics compared to the Not Academics Group. Moreover, the h-index values increased more regularly as the career length progressed than the hc-index values, even if the last seemed to be less variable. h- and hc-indices are both stable bibliometric parameters, but as the hc-index values are related not only to the number of citation but also to their age, it seems to be less influenced by the authors' career length. Bibliometric analysis of the scientific production in dentistry may facilitate the recognition of factors that may further enhance research activity and clinical performance and be useful for a comparative assessment of authors or research groups in terms of quality and quantity of the scientific production.

  5. Analog to digital workflow improvement: a quantitative study.

    PubMed

    Wideman, Catherine; Gallet, Jacqueline

    2006-01-01

    This study tracked a radiology department's conversion from utilization of a Kodak Amber analog system to a Kodak DirectView DR 5100 digital system. Through the use of ProModel Optimization Suite, a workflow simulation software package, significant quantitative information was derived from workflow process data measured before and after the change to a digital system. Once the digital room was fully operational and the radiology staff comfortable with the new system, average patient examination time was reduced from 9.24 to 5.28 min, indicating that a higher patient throughput could be achieved. Compared to the analog system, chest examination time for modality specific activities was reduced by 43%. The percentage of repeat examinations experienced with the digital system also decreased to 8% vs. the level of 9.5% experienced with the analog system. The study indicated that it is possible to quantitatively study clinical workflow and productivity by using commercially available software.

  6. The Bibliometric Properties of Article Readership Information

    NASA Astrophysics Data System (ADS)

    Kurtz, Michael J.; Eichhorn, Guenther; Accomazzi, Alberto; Grant, Carolyn S.; Demleitner, Markus; Murray, Stephen S.; Martimbeau, Nathalie; Elwell, Barbara

    The NASA Astrophysics Data System (ADS), along with astronomy's journals and data centers (a collaboration dubbed URANIA), has developed a distributed on-line digital library which has become the dominant means by which astronomers search, access and read their technical literature. Digital libraries such as the NASA Astrophysics Data System \\citep{2005JASIS.tmp....2K} permit the easy accumulation of a new type of bibliometric measure, the number of electronic accesses (``reads'') of individual articles. We explore various aspects of this new measure. We examine the obsolescence function as measured by actual reads, and show that it can be well fit by the sum of four exponentials with very different time constants. We compare the obsolescence function as measured by readership with the obsolescence function as measured by citations. We find that the citation function is proportional to the sum of two of the components of the readership function. This proves that the normative theory of citation is true in the mean. We further examine in detail the similarities and differences between the citation rate, the readership rate and the total citations for individual articles, and discuss some of the causes. Using the number of reads as a bibliometric measure for individuals, we introduce the read-cite diagram to provide a two-dimensional view of an individual's scientific productivity. We develop a simple model to account for an individual's reads and cites and use it to show that the position of a person in the read-cite diagram is a function of age, innate productivity, and work history. We show the age biases of both reads and cites, and develop two new bibliometric measures which have substantially less age bias than citations: SumProd, a weighted sum of total citations and the readership rate, intended to show the total productivity of an individual; and Read10, the readership rate for papers published in the last ten years, intended to show an individual's current

  7. Nuclear medicine and imaging research: Quantitative studies in radiopharmaceutical science

    SciTech Connect

    Copper, M.; Beck, R.N.

    1991-06-01

    During the past three years the program has undergone a substantial revitalization. There has been no significant change in the scientific direction of this grant, in which emphasis continues to be placed on developing new or improved methods of obtaining quantitative data from radiotracer imaging studies. However, considerable scientific progress has been made in the three areas of interest: Radiochemistry, Quantitative Methodologies, and Experimental Methods and Feasibility Studies, resulting in a sharper focus of perspective and improved integration of the overall scientific effort. Changes in Faculty and staff, including development of new collaborations, have contributed to this, as has acquisition of additional and new equipment and renovations and expansion of the core facilities. 121 refs., 30 figs., 2 tabs.

  8. Cytoarchitectonic and quantitative Golgi study of the hedgehog supraoptic nucleus.

    PubMed Central

    Caminero, A A; Machín, C; Sanchez-Toscano, F

    1992-01-01

    A cytoarchitectural study was made of the supraoptic nucleus (SON) of the hedgehog with special attention to the quantitative comparison of its main neuronal types. The main purposes were (1) to relate the characteristics of this nucleus in the hedgehog (a primitive mammalian insectivorous brain) with those in the SONs of more evolutionarily advanced species; (2) to identify quantitatively the dendritic fields of the main neuronal types in the hedgehog SON and to study their synaptic connectivity. From a descriptive standpoint, 3 neuronal types were found with respect to the number of dendritic stems arising from the neuronal soma: bipolar neurons (48%), multipolar neurons (45.5%) and monopolar neurons (6.5%). Within the multipolar type 2 subtypes could be distinguished, taking into account the number of dendritic spines: (a) with few spines (93%) and (b) very spiny (7%). These results indicate that the hedgehog SON is similar to that in other species except for the very spiny neurons, the significance of which is discussed. In order to characterise the main types more satisfactorily (bipolar and multipolars with few spines) we undertook a quantitative Golgi study of their dendritic fields. Although the patterns of the dendritic field are similar in both neuronal types, the differences in the location of their connectivity can reflect functional changes and alterations in relation to the synaptic afferences. Images Fig. 2 Fig. 3 Fig. 5 Fig. 6 Fig. 7 Fig. 8 Fig. 9 PMID:1452481

  9. [10 years of literature on AIDS (1983-1992): bibliometric analysis].

    PubMed

    Aleixandre, R; de la Cueva, A; Almero, A; Osca, J; Giménez, J V

    1995-01-01

    Reasons for the quantitative study of the Spanish publications on AIDS are both the huge volume attained by the printed material on the subject since the first case was described in 1981 by the Center for Disease Control, and the high incidence of the cases reported on this disease. Searches have been performed on the subject through the database of the Indice Médico Español (IME), the Indice Español de Ciencia y Technología (ICYT), the ISBN and Bibliografía Española in order to retrieve all possible Spanish journal papers' and books. The references were distributed using criteria of documentary tipology, publication date, institutions involved, autonomous communities, and, finally, after its relation with the confirmed cases of AIDS. A total 2,013 items have been retrieved, 1,821 journal papers' and 192 books. More than 50% of the papers are published only by five journals, being 139 the total number of journals able to carry pertinent information. The most productive journals were Medicina Clínica and Enfermedades Infecciosas y Microbiología Clínica. The results confirm exponential growth of the publications from 1983, the first year when a paper was published on AIDS in Spain. The grow is similar to the tend observed in other countries. Parallelism has been detected between growth in the number of publications and in the number of journals publishing on the subject, the growth in the number of journals publishing on the subject, the growth in the number of institutions which collaborate and the growing tend of reported cases in Spain. The results of the bibliometric study, showing an epidemiological growth out of comparison in the history of the scientific literature, could be useful both to information scientists, and to the research inside this scientific field.

  10. A Quantitative Study of Bulk Stresses in Nonlinear Microrheology

    NASA Astrophysics Data System (ADS)

    Depuit, Ryan; Squires, Todd

    2010-11-01

    We investigate the nonlinear microrheology of a simple model system - a spherical probe translating through a dilute suspension of rigid rods - to elucidate a variety of issues inherent in the interpretation of nonlinear microrheology. We have developed a computational system to quantitatively examine the issues present in interpretation of nonlinear microrheology, as originally discussed by Squires (Langmuir, 2008). Following recent work emphasizing the importance of the microstructural behavior in the bulk (Sriram et. al, 2009), we focus our attention on the bulk microstructural deformation, and examine the significance of its (Lagrangian) transient nature, as well as the consequences of the mixed and inhomogeneous flows inherent to nonlinear microrheology. From this quantitative study, we pose solutions for the current theoretical issues facing nonlinear microrheology in interpretation and comparison of the microviscosity with the shear viscosity from traditional bulk rheometry.

  11. Limitations of quantitative research in the study of structural adjustment.

    PubMed

    Lundy, P

    1996-02-01

    Sociologists and, more recently, critical medical anthropologists have been arguing for a refocusing of the analysis of health and health care towards a perspective which considers the broader global political economy. In the context of the debt crisis and IMF/World Bank-inspired structural adjustment policies, the political economy theoretical perspective is becoming even more relevant in the analysis of health underdevelopment in many 'Third World' countries. This study focuses on the direct and indirect effects of the Jamaican debt crisis and structural adjustment programmes on health care services and health standards. In this paper it is argued that there are methodological problems using quantitative data when studying the effects of structural adjustment. In addition to providing a limited account of the effects, it is argued that the basic problem is a matter of the availability and reliability of the quantitative data in many 'Third World' countries. It is argued that some of these problems could be overcome by the application of qualitative micro-level analysis. This type of methodology is important to ascertain the effects of global processes at the grass roots level and to gain insights into what those working in the health sector are experiencing and what they perceive as the effects, if any, of structural adjustment policies. This has often been missing from the impersonal accounts offered by quantitative research on the subject to date.

  12. How Implementation of Bibliometric Practice Affects the Role of Academic Libraries

    ERIC Educational Resources Information Center

    Åström, Fredrik; Hansson, Joacim

    2013-01-01

    This article discusses potential consequences of implementing bibliometrics as an institutionalized practice in academic libraries. Results are reported from a survey among libraries in Sweden with organized bibliometric activities. Incorporating bibliometric activities is one way of redefining and widening the role of the library. Implementation…

  13. Bibliometrics Course Offerings by Library and Information Science Programs in China

    ERIC Educational Resources Information Center

    Xiao, Ming; Zhao, Dangzhi; Yin, Yali; Yu, Jia

    2016-01-01

    In this article, we report results from a survey of bibliometrics courses offered by LIS programs in mainland China. We found that more than 27% of Chinese LIS programs offer bibliometrics courses. The majority of these programs teach bibliometrics as 2- or 3-credit, required courses to both undergraduate and graduate students, indicating the…

  14. Bibliometrics Course Offerings by Library and Information Science Programs in China

    ERIC Educational Resources Information Center

    Xiao, Ming; Zhao, Dangzhi; Yin, Yali; Yu, Jia

    2016-01-01

    In this article, we report results from a survey of bibliometrics courses offered by LIS programs in mainland China. We found that more than 27% of Chinese LIS programs offer bibliometrics courses. The majority of these programs teach bibliometrics as 2- or 3-credit, required courses to both undergraduate and graduate students, indicating the…

  15. How Implementation of Bibliometric Practice Affects the Role of Academic Libraries

    ERIC Educational Resources Information Center

    Åström, Fredrik; Hansson, Joacim

    2013-01-01

    This article discusses potential consequences of implementing bibliometrics as an institutionalized practice in academic libraries. Results are reported from a survey among libraries in Sweden with organized bibliometric activities. Incorporating bibliometric activities is one way of redefining and widening the role of the library. Implementation…

  16. Quantitative measurement of tooth and ceramic wear: in vivo study.

    PubMed

    Etman, Maged K; Woolford, Mark; Dunne, Stephen

    2008-01-01

    The aim of this study was to quantitatively measure tooth and ceramic wear over a 2-year period using a novel superimposition technique. Three ceramic systems--experimental hot-pressed ceramic (EC), Procera AllCeram (PA), and metal-ceramic--were used. A total of 90 posterior crowns in 48 patients were randomized into 3 groups, and impressions were made at baseline and at 6-month intervals for 2 years. Clinical images were taken after using a dye to highlight surface changes. The impressions were digitized and modeled as superimposable 3-dimensional colored surface images. The depth of wear at the occlusal contact areas was quantitatively measured at 6, 12, 18, and 24 months. The quantitative evaluation showed more wear in Procera AllCeram at the occlusal contact areas, whereas the experimental and metal-ceramic systems showed less wear. There was a significant difference in the amount of enamel worn between all types of restorations (P < .05). There was a statistically significant difference (P < .05) in the mean depth of wear between all systems. The metal-ceramic and experimental systems showed less change, indicating improved wear resistance compared with Procera AllCeram. In addition, enamel opposing metal-ceramic and experimental crowns showed less wear compared to enamel opposed by Procera AIICeram crowns.

  17. Splash erosion. A bibliometric Review

    NASA Astrophysics Data System (ADS)

    Fernández Raga, M. B.

    2012-04-01

    Ellison (1944) developed the splash board as a system for measuring splash erosion that was both cheap and reliable. Bollinne (1975), Morgan (1978, 1981). Mutchler (1967) described another different type of splash detectors according to whether they were passive or could register data. In the study mentioned above these authors included bottles, funnels, glasses, photography, markers. After that several devices has been made up like the splash sampler (Leguedois et al., 2005), soil tray (Van Dijk et al., 2002), splash funnel (Terry, 1989) and several rain cups (Fernandez-Raga et al., 2010; Molina and Llinares, 1996; Torri et al., 1987). Splash erosion research has materialized in the form of a number of papers published in international journals. The database of bibliographic references employed has been one of the most prestigious ones: theWeb of Science (ISI). The search was carried out on January 27th 2012. Among the 3x10^8 scholarly documents included in the Science Citation Index Expanded (SCI-EXPANDED) 1899 to present , the searching engine located 439 containing the word "splash erosion*", where the asterisk acts as a wildcard for any letter or group of letters. Of these, 383 were classified as articles, 87 as proceeding papers, 5 as editorial material, 2 as notes and 1 as correction. These documents have been published in 163 different journals, although four are particularly recurrent: Earth surface processes and Landforms, Catena, Soil Science Society of America Journal and Hydrological processes, with 41, 35, 35 and 26 published documents respectively. A geographic analysis of these articles has been carried out in an attempt to determine in what parts of the world research projects were making use of splash erosion. The results are that anglo-saxon countries, as USA, England and Australia dominate, particularly USA, with 130 articles. China and Japan are large communities of researches too, and some Central European countries as Belgium, France Germany

  18. Groundwater remediation from the past to the future: A bibliometric analysis.

    PubMed

    Zhang, Shu; Mao, Guozhu; Crittenden, John; Liu, Xi; Du, Huibin

    2017-08-01

    Groundwater is an important component of terrestrial ecosystems and plays a role in geochemical cycling. Groundwater is also used for agricultural irrigation and for the domestic supply of drinking water in most nations. However, groundwater contamination has led to many research efforts on groundwater remediation technologies and strategies. This study evaluated a total of 5486 groundwater remediation-related publications from 1995 to 2015 using bibliometric technology and social network analysis, to provide a quantitative analysis and a global view on the current research trend and future research directions. Our results underline a strong research interest and an urgent need to remediate groundwater pollution due to the increasing number of both groundwater contamination and remediation publications. In the past two decades, the United States (U.S.) published 41.1% of the papers and it was the core country of the international collaboration network, cooperating with the other 19 most productive countries. Besides the active international collaboration, the funding agencies also played positive roles to foster the science and technology publications. With respect to the analysis of the distribution of funding agencies, the National Science Foundation of China sponsored most of the groundwater remediation research. We also identified the most productive journals, Environmental Science and Technology and Journal of Contaminant Hydrology, which published 334 and 259 scientific articles (including research articles and reviews) over the past 20 years, respectively. In addition to journal publications, a patent analysis was performed to show the impact of intellectual property protection on journal publications. Three major remediation technologies, including chemical oxidation, biodegradation and adsorption, have received increasing interest in both journal publication and patent development. Our results provide a valuable reference and global overview to identify

  19. [Bibliometric analysis of the Spanish scientific production in Infectious Diseases and Microbiology].

    PubMed

    Ramos, José Manuel; González-Alcaide, Gregorio; Gutiérrez, Félix

    2016-03-01

    The bibliometric analysis of production and impact of documents by knowledge area is a quantitative and qualitative indicator of research activity in this field. The aim of this article is to determine the contribution of Spanish research institutions in Infectious Diseases and Microbiology in recent years. Documents published in the journals included in the categories "Infectious Diseases" and "Microbiology" of the Web of Science (Science Citation Index Expanded) of the ISI Web of Knowledge from the year 2000-2013 were analysed. In Infectious Diseases, Spain ranked fourth worldwide, and contributed 5.7% of the 233,771 documents published in this specialty. In Microbiology, Spain was in sixth place with a production rate of 5.8% of the 149,269 documents of this category. The Spanish production increased over the study period, both in Infectious Diseases and Microbiology, from 325 and 619 documents in 2000 to 756 and 1245 documents in 2013, with a growth rate of 131% and 45.8%, respectively. The journal with the largest number of documents published was Enfermedades Infecciosas y Microbiología Clínica, with 8.6% and 8.2% of papers published in the categories of Infectious Diseases and Microbiology, respectively, and was the result of international collaborations, especially with institutions in the United States. The "index h" was 116 and 139 in Infectious Diseases and Microbiology, placing Spain in fifth place in both categories within countries of the European Union. In recent years, Spanish research in Infectious Diseases and Microbiology has reached a good level of production and international visibility, reaching a global leadership position. Copyright © 2015. Published by Elsevier España, S.L.U.

  20. From bibliometric analysis to research policy: the use of SIGAPS in Lille University Hospital.

    PubMed

    Devos, Patrick; Lefranc, Helene; Dufresne, Eric; Beuscart, Regis

    2006-01-01

    In French hospitals, the progressive setting up of the new rating systems has obliged the university hospitals to justify a certain amount of activities such as research, training or moreover recourse, which are specific missions of the university hospitals. In order to justify research activities, the Lille University Hospital has developed for now three years SIGAPS, a full-web bibliometric software which census and analyse, the scientific publications referenced in the Medline database. After data downloading, each article is classified on a 6 levels "quality scale derived from the impact factors. The system then performs, for a researcher or a team, a report allowing a quantitative and qualitative analysis. Started in Lille in November 2004, the inventory and analysis of data is now ending. For the period 2001-2004, 2814 articles have been published in 700 different journals. The total number of articles increased from 688 in 2001 to 757 in 2004. The mean impact factor was equal to 2.26 and 15.5 % of articles were classified as A, 20.9% as B. Those results confirm the high level of research of the University Hospital of Lille, in agreement with two other national studies which ranks our establishment at the 6th position for medical research activities among the French University Hospitals. Currently a similar evaluation has now began in the 9 other university hospital which have subscribed to the SIGAPS project. We works currently on new indicators as patents, thesis or conferences, or access to other databases as Sciencedirect or Scopus via the RIS format. The next step in the project is the implementation of a meta-base which will federate the information provided by each SIGAPS system. This meta-base will then allow us to perform comparisons between different hospitals, determine the national "sites of excellence" and create some clinical and research networks.

  1. [Bibliometric study of the original articles published in Revista Española de Salud Púiblica (1991-2000). Part III: reference analysis].

    PubMed

    Villar Alvarez, Fernando; Estrada Lorenzo, José Manuel; Peréz Andrés, Christina; Rebollo Rodríguez, M José

    2007-01-01

    The advancement of knowledge is based on the results of previously conducted research studies, which are reflected in the reference sources listed in a scientific article. This study is aimed at studying the scientific information used in the Revista Española de Salud Pública based on the references cited in the original articles published during the 1991-2000 period. The data regarding the year and where published, document type, language and country in which published was taken from the reference sources listed in the 290 original articles published, the obsolescence, Price and isolation indexes being calculated, and the Bradford core distribution being established according to the source journals. The self-citing rate was also calculated. A total of 7465 references were cited in the Reference section of the 290 original articles. An average of 25.7 references were cited per article. The Price index was 40.7. The scientific articles showed an obsolescence index of 5, the books and book chapters having an index of 6. A total 50.6% of the citations were from studies published in Spanish. The isolation index of the references was 48.1. The first Bradford core is comprised of 10 journals, the first four of which are Spanish. The self-citing rate was 3.8%. The information consumption of the original articles published in the Revista Española de Salud Pública show parameters similar to those of other Spanish health sciences journals for those same years, and the parameters regarding which this Journal differs from other Spanish health sciences journals seem to be justified by those particular aspects unique to public health, which does not fall within the patterns inherent to the clinical disciplines.

  2. Integration of hydrothermal-energy economics: related quantitative studies

    SciTech Connect

    Not Available

    1982-08-01

    A comparison of ten models for computing the cost of hydrothermal energy is presented. This comparison involved a detailed examination of a number of technical and economic parameters of the various quantitative models with the objective of identifying the most important parameters in the context of accurate estimates of cost of hydrothermal energy. Important features of various models, such as focus of study, applications, marked sectors covered, methodology, input data requirements, and output are compared in the document. A detailed sensitivity analysis of all the important engineering and economic parameters is carried out to determine the effect of non-consideration of individual parameters.

  3. Quantitative study of protein-protein interactions by quartz nanopipettes

    NASA Astrophysics Data System (ADS)

    Tiwari, Purushottam Babu; Astudillo, Luisana; Miksovska, Jaroslava; Wang, Xuewen; Li, Wenzhi; Darici, Yesim; He, Jin

    2014-08-01

    In this report, protein-modified quartz nanopipettes were used to quantitatively study protein-protein interactions in attoliter sensing volumes. As shown by numerical simulations, the ionic current through the conical-shaped nanopipette is very sensitive to the surface charge variation near the pore mouth. With the appropriate modification of negatively charged human neuroglobin (hNgb) onto the inner surface of a nanopipette, we were able to detect concentration-dependent current change when the hNgb-modified nanopipette tip was exposed to positively charged cytochrome c (Cyt c) with a series of concentrations in the bath solution. Such current change is due to the adsorption of Cyt c to the inner surface of the nanopipette through specific interactions with hNgb. In contrast, a smaller current change with weak concentration dependence was observed when Cyt c was replaced with lysozyme, which does not specifically bind to hNgb. The equilibrium dissociation constant (KD) for the Cyt c-hNgb complex formation was derived and the value matched very well with the result from surface plasmon resonance measurement. This is the first quantitative study of protein-protein interactions by a conical-shaped nanopore based on charge sensing. Our results demonstrate that nanopipettes can potentially be used as a label-free analytical tool to quantitatively characterize protein-protein interactions.In this report, protein-modified quartz nanopipettes were used to quantitatively study protein-protein interactions in attoliter sensing volumes. As shown by numerical simulations, the ionic current through the conical-shaped nanopipette is very sensitive to the surface charge variation near the pore mouth. With the appropriate modification of negatively charged human neuroglobin (hNgb) onto the inner surface of a nanopipette, we were able to detect concentration-dependent current change when the hNgb-modified nanopipette tip was exposed to positively charged cytochrome c (Cyt c) with

  4. Quantitative Methods in the Study of Local History

    ERIC Educational Resources Information Center

    Davey, Pene

    1974-01-01

    The author suggests how the quantitative analysis of data from census records, assessment roles, and newspapers may be integrated into the classroom. Suggestions for obtaining quantitative data are provided. (DE)

  5. Quantitative Methods in the Study of Local History

    ERIC Educational Resources Information Center

    Davey, Pene

    1974-01-01

    The author suggests how the quantitative analysis of data from census records, assessment roles, and newspapers may be integrated into the classroom. Suggestions for obtaining quantitative data are provided. (DE)

  6. Bibliometric analysis of publications on Campylobacter: (2000-2015).

    PubMed

    Sweileh, Waleed M; Al-Jabi, Samah W; Sawalha, Ansam F; AbuTaha, Adham S; Zyoud, Sa'ed H

    2016-11-29

    Campylobacter species are widespread zoonotic pathogens. Campylobacter jejuni causes a form of gastroenteritis called campylobacteriosis. Campylobacter drug resistance is considered a serious threat. In order to better understand national and international research output on Campylobacter, we conducted this bibliometric overview of publications on Campylobacter. This study can be used to assess extent of interaction and response of researchers, food regulators, and health policy makers to global burden of campylobacateriosis. Scopus database was used to retrieve publications with the following keywords (Campylobacter/campylobacteriosis, C. jejuni, C. coli). The study period was set from 2000 to 2015. All types of journal documents, excluding errata, were considered. Bibliometric indicators such as annual growth of publications, country contribution, international collaboration, and citation analysis were presented. The quality of retrieved data was indirectly assessed by Hirsch index and impact factor of journals. A total of 5522 documents were retrieved with median (Q1-Q3) citations of 9 (2-23) and h-index of 113. Annual number of publications showed a fluctuating increase. The core leading journals were Applied and Environmental Microbiology journal and Journal of Food Protection with 246 (4.46%) publications for each. The USA (1309; 23.6%) was the most productive country while Danmarks Tekniske Universitet (150; 2.7%) was the most productive institution. Half of the top ten productive countries were European. France had the lowest percentage (33.5%) of articles with international collaboration while Netherlands (57.7%) had the highest percentage of articles with international collaboration. Approximately half (50.1%) of retrieved articles were published in journals under the subject area of "immunology/microbiology". Main themes in highly cited articles were molecular biology/genetics and public health burden of campylobacteriosis. There were 728 (13

  7. [Hot research topics on cardiovascular diseases in occupational population: a bibliometric analysis].

    PubMed

    Zheng, P; Li, C Y; Hu, G P; Jia, G

    2016-10-20

    Objective: To investigate the literature characteristics and research topics on cardiovascular diseases in the occupational population quantitatively via a bibliometric analysis, and to provide a reference for the selection of research directions. Methods: A search strategy was developed according to the words in Medical Subject Heading (MeSH) , and PubMed database was searched for articles on cardiovascular diseases in the occupational population published from 2006 to 2015. The information of published year, authors, journals, and MeSH words was extracted, frequently used MeSH words were screened out, and a cluster analysis was performed for frequently used MeSH words. Results: A total of 1 272 articles were found, and about 150 articles were published annually from 2011 to 2015. Most articles were published in Occupational and Environmental Medicine, and the author Tohr Nilsson had the highest number of published articles. The influencing factors mainly included occupational mental stress, smoking, and working system, and the health outcomes attracting the most attention were hypertension, hand-arm vibration, ischemic heart disease, and myocardial infarction. The articles were clustered into 5 types, and 5 hot topics were summarized. Conclusion: The bibliometric analysis of cardiovascular diseases in occupational population shows that hypertension and hand-arm vibration are hot research topics, which can provide a reference to researchers.

  8. Quantitative Courses in a Liberal Education Program: A Case Study

    ERIC Educational Resources Information Center

    Wismath, Shelly L.; Mackay, D. Bruce

    2012-01-01

    This essay argues for the importance of quantitative reasoning skills as part of a liberal education and describes the successful introduction of a mathematics-based quantitative skills course at a small Canadian university. Today's students need quantitative problem-solving skills, to function as adults, professionals, consumers, and citizens in…

  9. Quantitative Courses in a Liberal Education Program: A Case Study

    ERIC Educational Resources Information Center

    Wismath, Shelly L.; Mackay, D. Bruce

    2012-01-01

    This essay argues for the importance of quantitative reasoning skills as part of a liberal education and describes the successful introduction of a mathematics-based quantitative skills course at a small Canadian university. Today's students need quantitative problem-solving skills, to function as adults, professionals, consumers, and citizens in…

  10. Ethics and dementia: mapping the literature by bibliometric analysis.

    PubMed

    Baldwin, Clive; Hughes, Julian; Hope, Tony; Jacoby, Robin; Ziebland, Sue

    2003-01-01

    This paper reports on a bibliometric analysis of keywords in the literature on ethics and dementia during the period 1980-2000. Keywords were drawn from titles, abstracts and keyword fields of 14 bibliographic databases and clustered in to 19 categories. These categories were then examined for their frequency and co-occurrences. The strength of relationships between these categories is mapped using the metaphor of the 'night sky' showing constellations of issues and changes over time. Four categories appear consistently and frequently in the literature: professional care, end-of-life issues, decision-making and treatment. Other issues come and go (such as quality-of-life issues) while others appear to respond to outside events (e.g. feeding issues). The research literature is based predominantly on surveys or studies soliciting responses to predefined issues. Little research has been undertaken to establish the range of ethical issues for either family members or professionals. We discuss the domination of the literature by four categories of ethical issues, the new and emerging areas of ethical interest and those areas that are triggered by external events such as legal cases. We also discuss some of the limitations of the study and note some omissions in the literature. During the period 1980-2000 the research literature has been dominated by surveys and studies soliciting views on predefined issues with relatively few in-depth, open-ended qualitative studies. Copyright 2002 John Wiley & Sons, Ltd.

  11. A quantitative study of oxygen as a metabolic regulator

    NASA Technical Reports Server (NTRS)

    Radhakrishnan, Krishnan; LaManna, Joseph C.; Cabrera, Marco E.

    2003-01-01

    An acute reduction in oxygen delivery to a tissue is associated with metabolic changes aimed at maintaining ATP homeostasis. However, given the complexity of the human bioenergetic system, it is difficult to determine quantitatively how cellular metabolic processes interact to maintain ATP homeostasis during stress (e.g., hypoxia, ischemia, and exercise). In particular, we are interested in determining mechanisms relating cellular oxygen concentration to observed metabolic responses at the cellular, tissue, organ, and whole body levels and in quantifying how changes in tissue oxygen availability affect the pathways of ATP synthesis and the metabolites that control these pathways. In this study, we extend a previously developed mathematical model of human bioenergetics, to provide a physicochemical framework that permits quantitative understanding of oxygen as a metabolic regulator. Specifically, the enhancement--sensitivity analysis--permits studying the effects of variations in tissue oxygenation and parameters controlling cellular respiration on glycolysis, lactate production, and pyruvate oxidation. The analysis can distinguish between parameters that must be determined accurately and those that require less precision, based on their effects on model predictions. This capability may prove to be important in optimizing experimental design, thus reducing use of animals.

  12. A quantitative study of oxygen as a metabolic regulator

    NASA Technical Reports Server (NTRS)

    Radhakrishnan, Krishnan; LaManna, Joseph C.; Cabrera, Marco E.

    2003-01-01

    An acute reduction in oxygen delivery to a tissue is associated with metabolic changes aimed at maintaining ATP homeostasis. However, given the complexity of the human bioenergetic system, it is difficult to determine quantitatively how cellular metabolic processes interact to maintain ATP homeostasis during stress (e.g., hypoxia, ischemia, and exercise). In particular, we are interested in determining mechanisms relating cellular oxygen concentration to observed metabolic responses at the cellular, tissue, organ, and whole body levels and in quantifying how changes in tissue oxygen availability affect the pathways of ATP synthesis and the metabolites that control these pathways. In this study, we extend a previously developed mathematical model of human bioenergetics, to provide a physicochemical framework that permits quantitative understanding of oxygen as a metabolic regulator. Specifically, the enhancement--sensitivity analysis--permits studying the effects of variations in tissue oxygenation and parameters controlling cellular respiration on glycolysis, lactate production, and pyruvate oxidation. The analysis can distinguish between parameters that must be determined accurately and those that require less precision, based on their effects on model predictions. This capability may prove to be important in optimizing experimental design, thus reducing use of animals.

  13. A Quantitative Study of Oxygen as a Metabolic Regulator

    NASA Technical Reports Server (NTRS)

    Radhakrishnan, Krishnan; LaManna, Joseph C.; Cabera, Marco E.

    2000-01-01

    An acute reduction in oxygen delivery to a tissue is associated with metabolic changes aimed at maintaining ATP homeostasis. However, given the complexity of the human bio-energetic system, it is difficult to determine quantitatively how cellular metabolic processes interact to maintain ATP homeostasis during stress (e.g., hypoxia, ischemia, and exercise). In particular, we are interested in determining mechanisms relating cellular oxygen concentration to observed metabolic responses at the cellular, tissue, organ, and whole body levels and in quantifying how changes in tissue oxygen availability affect the pathways of ATP synthesis and the metabolites that control these pathways. In this study; we extend a previously developed mathematical model of human bioenergetics, to provide a physicochemical framework that permits quantitative understanding of oxygen as a metabolic regulator. Specifically, the enhancement - sensitivity analysis - permits studying the effects of variations in tissue oxygenation and parameters controlling cellular respiration on glycolysis, lactate production, and pyruvate oxidation. The analysis can distinguish between parameters that must be determined accurately and those that require less precision, based on their effects on model predictions. This capability may prove to be important in optimizing experimental design, thus reducing use of animals.

  14. Medical informatics and bioinformatics: a bibliometric study

    PubMed Central

    Bansard, Jean-Yves; Rebholz-Schuhman, Dietrich; Cameron, Graham; Clark, Dominic; van Mulligen, Erik; Beltrame, Francesco; Del Hoyo Barbolla, Eva; Martin-Sanchez, Fernando; Milanesi, Luciano; Tollis, Ioannis; Van der Lei, Johan; Coatrieux, Jean-Louis

    2007-01-01

    This paper reports on an analysis of the bioinformatics and medical informatics literature with the objective to identify upcoming trends that are shared among both research fields to derive benefits from potential collaborative initiatives for their future. Our results present the main characteristics of the two fields and show that these domains are still relatively separated. PMID:17521073

  15. Quantitative model studies for interfaces in organic electronic devices

    NASA Astrophysics Data System (ADS)

    Gottfried, J. Michael

    2016-11-01

    In organic light-emitting diodes and similar devices, organic semiconductors are typically contacted by metal electrodes. Because the resulting metal/organic interfaces have a large impact on the performance of these devices, their quantitative understanding is indispensable for the further rational development of organic electronics. A study by Kröger et al (2016 New J. Phys. 18 113022) of an important single-crystal based model interface provides detailed insight into its geometric and electronic structure and delivers valuable benchmark data for computational studies. In view of the differences between typical surface-science model systems and real devices, a ‘materials gap’ is identified that needs to be addressed by future research to make the knowledge obtained from fundamental studies even more beneficial for real-world applications.

  16. Bibliometric analysis of rheumatology research in the Arab countries.

    PubMed

    Bayoumy, Karim; MacDonald, Ross; Dargham, Soha Roger; Arayssi, Thurayya

    2016-08-08

    The Arab world has seen an increase in the burden of musculoskeletal diseases. No bibliometric studies have characterized rheumatology research in the Arab world. This study evaluates the productivity and impact of rheumatology research in the Arab world. We searched the Web of Science Core Collection for rheumatology publications, from 1976 to 2014, for each of the Arab League (AL) countries, North America, Europe and Asia. For the AL countries, the overall trend of publications and citations was analyzed, while considering the paper type and collaborations. The AL countries published 944 rheumatology papers over the period studied. The number of publications increased by a factor of 2.77 (95 % CI, 2.75-2.78) each decade, and citations increased by a factor of 2.36 (95 % CI, 0.96-5.82). The absolute number of papers included in the top-10 rheumatology journals remained constant but the proportion decreased. Papers involving collaboration among AL countries were found to increase over time. Overall, the AL countries lag in research productivity and impact compared to other regions. Three countries are responsible for the majority of publications, while four countries receive the majority of citations.

  17. Top-100 cited articles on headache disorders: A bibliometric analysis.

    PubMed

    Park, Kang Min; Park, Bong Soo; Park, Sihyung; Yoon, Dae Young; Bae, Jong Seok

    2017-06-01

    The purpose of this study was to identify and characterize the most-cited articles on headache disorders published in journals that have made key contributions in the field. We performed a search of journals and selected the top-100 cited articles by utilizing the Institute for Scientific Information database available under the banner of the Web of Science, which provides the most relevant bibliometric information on scientific articles published since 1950. The top-100 cited articles were published in 20 journals. The most frequently cited journal was Neurology (19 articles), and followed by Cephalagia (15 articles) and Headache (15 articles). Migraine was the most common topic subject (81 articles), and original articles predominated (91 articles). The topics of the classic articles had varied from decade to decade. The most common topic subject was epidemiology (37 articles), followed by pathophysiology (20 articles), treatment (18 articles), review (10 articles), neuroimaging (11 articles), genetics (3 articles), and diagnostic tools (2 articles). The present study has produced a detailed list of the most-cited articles on headache disorders, which is the first such study in this field. This list makes it possible to recognize the classic articles on headache disorders as well as research trends and academic achievements in this field. Copyright © 2017. Published by Elsevier B.V.

  18. [Quantitative computerized tomography in the study of osteoporosis. Our experience].

    PubMed

    Mecozzi, B; Anselmetti, G C

    1992-01-01

    In the diagnosis of osteoporosis there are, today, several techniques for investigating bone mineral density. In this work the authors evaluate the sensitivity of Computed Tomography in the diagnosis of this metabolic disease, because of the built-in competence of this method in determining the density of the anatomical tissues. In a randomised study the Authors performed Single Energy Quantitative Computed Tomography (SEQCT) in estimating the bone mineral density of lumbar vertebrae in 44 female patients. The data obtained were correlated, using the Student "t" test, to the measurements acquired, in the same group of patients, employing Dual Energy X-ray Absorptiometry (DEXA), 27 patients, and Total Body DEXA, 17 patients. Results revealed a good correlation between SEQCT and DEXA (R = 0.89) and statistical significance (p < 0.001). On the contrary there is not a good correlation (R = 0.58) if SEQCT is compared to Total Body DEXA. According to our experience Quantitative Computed Tomography is useful in diagnosis osteoporosis and it should be performed in all post-menopausal patients. This method, which has a high level of precision, is cheap and easily adaptable to every Computed Tomography. Because of the high X-ray dose rate, only DEXA should be performed in monitoring patients undergoing therapy.

  19. Quantitative study on appearance of microvessels in spectral endoscopic imaging

    NASA Astrophysics Data System (ADS)

    Yamaguchi, Hiroshi; Saito, Takaaki; Shiraishi, Yasushi; Arai, Fumihito; Morimoto, Yoshinori; Yuasa, Atsuko

    2015-03-01

    Increase in abnormal microvessels in the superficial mucosa is often relevant to diagnostic findings of neoplasia in digestive endoscopy; hence, observation of superficial vasculature is crucial for cancer diagnosis. To enhance the appearance of such vessels, several spectral endoscopic imaging techniques have been developed, such as narrow-band imaging and blue laser imaging. Both techniques exploit narrow-band blue light for the enhancement. The emergence of such spectral imaging techniques has increased the importance of understanding the relation of the light wavelength to the appearance of superficial vasculature, and thus a new method is desired for quantitative analysis of vessel visibility in relation to the actual structure in the tissue. Here, we developed microvessel-simulating phantoms that allowed quantitative evaluation of the appearance of 15-μm-thick vessels. We investigated the relation between the vascular contrast and light wavelength by the phantom measurements and also verified it in experiments with swine, where the endoscopically observed vascular contrast was investigated together with its real vascular depth and diameter obtained by microscopic observation of fluorescence-labeled vessels. Our study indicates that changing the spectral property even in the wavelength range of blue light may allow selective enhancement of the vascular depth for clinical use.

  20. Nuclear medicine and imaging research (quantitative studies in radiopharmaceutical science)

    SciTech Connect

    Cooper, M.D.; Beck, R.N.

    1990-09-01

    This is a report of progress in Year Two (January 1, 1990--December 31, 1990) of Grant FG02-86ER60438, Quantitative Studies in Radiopharmaceutical Science,'' awarded for the three-year period January 1, 1989--December 31, 1991 as a competitive renewal following site visit in the fall of 1988. This program addresses the problems involving the basic science and technology underlying the physical and conceptual tools of radioactive tracer methodology as they relate to the measurement of structural and functional parameters of physiologic importance in health and disease. The principal tool is quantitative radionuclide imaging. The overall objective of this program is to further the development and transfer of radiotracer methodology from basic theory to routine clinical practice in order that individual patients and society as a whole will receive the maximum net benefit from the new knowledge gained. The focus of the research is on the development of new instruments and radiopharmaceuticals, and the evaluation of these through the phase of clinical feasibility. 25 refs., 13 figs., 1 tab.

  1. Quantitative analysis of multiple sclerosis: a feasibility study

    NASA Astrophysics Data System (ADS)

    Li, Lihong; Li, Xiang; Wei, Xinzhou; Sturm, Deborah; Lu, Hongbing; Liang, Zhengrong

    2006-03-01

    Multiple Sclerosis (MS) is an inflammatory and demyelinating disorder of the central nervous system with a presumed immune-mediated etiology. For treatment of MS, the measurements of white matter (WM), gray matter (GM), and cerebral spinal fluid (CSF) are often used in conjunction with clinical evaluation to provide a more objective measure of MS burden. In this paper, we apply a new unifying automatic mixture-based algorithm for segmentation of brain tissues to quantitatively analyze MS. The method takes into account the following effects that commonly appear in MR imaging: 1) The MR data is modeled as a stochastic process with an inherent inhomogeneity effect of smoothly varying intensity; 2) A new partial volume (PV) model is built in establishing the maximum a posterior (MAP) segmentation scheme; 3) Noise artifacts are minimized by a priori Markov random field (MRF) penalty indicating neighborhood correlation from tissue mixture. The volumes of brain tissues (WM, GM) and CSF are extracted from the mixture-based segmentation. Experimental results of feasibility studies on quantitative analysis of MS are presented.

  2. Gunshot induced injuries in orthopaedic trauma research. A bibliometric analysis of the most influential literature.

    PubMed

    Held, M; Engelmann, E; Dunn, R; Ahmad, S S; Laubscher, M; Keel, M J B; Maqungo, S; Hoppe, S

    2017-09-01

    A growing burden of gunshot injuries demands evidence-based ballistic trauma management. No comprehensive systematic overview of the current knowledge is available to date. This study aims to identify and analyze the most influential publications in the field of orthopedic ballistic trauma research. All databases available in the Thomson Reuters Web of Knowledge were searched to conduct this bibliometrical study. The most cited orthopedic ballistic trauma articles published between 1950 and 2015 were identified by use of a multi-step approach. Publications with ten citations and more were analyzed for citations, journal, authorship, geographic origin, area of research, anatomical site, study type, study category, and level of evidence. Citations of the 128 included studies ranged from 113 to 10. These were published in fifty different journals between 1953 and 2011. Most publications (n=106; 83%) originated from the USA, were retrospective (n=85; 66.4%), level IV studies (n=90; 70.3%), reported on spinal gunshot injuries (n=49; 38.33%) and were published between 1980 and 2000 (n=111; 86.7%). This bibliometric study provides the first comprehensive overview of influential publications in the field of orthopedic ballistic trauma research. More prospective studies and high-quality systematic reviews are needed. Centres with a high burden of gunshot injuries from the developing world need to share their experience in form of international publications, to provide a more comprehensive picture of the global gun-related orthopedic injury burden. bibliometric analysis: level III. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  3. Arterial vasa vasorum: a quantitative study in the rat.

    PubMed Central

    McGeachie, J; Campbell, P; Simpson, S; Prendergast, F

    1982-01-01

    This study was designed to quantitate the vasa vasorum of common iliac arteries in 20 rats. The number of vasa vasorum per mm2 of arterial wall was extremely variable - from 0 to 124, the mean being 33 . 95 +/- 29 . 86 (S.D.). There was no significant difference in the vasa vasorum vascularity between the right and left common iliac arteries. The mean wall thickness of these arteries was 0 . 085 +/- 0 . 015 (S.D.) mm and 60 +/- 8% (S.D.) of this was made up by the tunica media. Arterial tissue in this study was shown to have approximately 10% of the vascularity of muscle tissue. By relating these data to the 'critical depth' hypothesis, on the nutritional supply of large arteries, it was concluded that the vasa vasorum in the common iliac arteries in rat (major arteries in small animals) probably play an insignificant role in the nutrition of the arterial wall. Images Fig. 1 PMID:7076548

  4. A Bibliometric Analysis of Publications on Pluripotent Stem Cell Research

    PubMed Central

    Lin, Changshuan L.; Ho, Yuh-Shan

    2015-01-01

    Objective Human pluripotent stem cells are self-renewing cells with the ability to differentiate into a variety of cells and are viewed to have great potential in the field of regenerative medicine. Research in pluripotent stem cells holds great promise for patient specific therapy in various diseases. In this study, pluripotent stem cell articles published from 1991 to 2012 were screened and retrieved from Science Citation Index Expanded (SCI-EXPANDED). Materials and Methods In this retrospective study, the publication trend, citation trends for top articles, distributions of journals and Web of Science categories were analyzed. Five bibliometric indicators including total articles, independent articles, collaborative articles, first author articles, and corresponding author articles were applied to compare publications between countries and institutions. Results The impact of top articles changed from year to year. Top cited articles in previous publication years were not the same as recent years. "Induced pluripotent stem cell (s)" and "embryonic stem cell (s)" were the most used author keywords in pluripotent stem cell research. In addition, the winner of the Nobel Prize in physiology or medicine in 2012, Prof. Shinya Yamanaka, published four of the top ten most frequently cited articles. Conclusion The comprehensive analysis of highly cited articles in the stem cell field could identify milestones and important contributors, giving a historic perspective on scientific progress. PMID:25870835

  5. Bibliometric analysis of the literature of randomized controlled trials

    PubMed Central

    Tsay, Ming-yueh; Yang, Yen-hsu

    2005-01-01

    Objective: Evidence-based medicine (EBM) is a significant issue and the randomized controlled trial (RCT) literature plays a fundamental role in developing EBM. This study investigates the features of RCT literature based on bibliometric methods. Growth of the literature, publication types, languages, publication countries, and research subjects are addressed. The distribution of journal articles was also examined utilizing Bradford's law and Bradford-Zipf's law. Method: The MEDLINE database was searched for articles indexed under the publication type “Randomized Control Trial,” and articles retrieved were counted and analyzed using Microsoft Access, Microsoft Excel, and PERL. Results: From 1990 to 2001, a total of 114,850 citations dealing with RCTs were retrieved. The literature growth rate, from 1965 to 2001, is steadily rising and follows an exponential model. Journal articles are the predominant form of publication, and the multicenter study is extensively used. English is the most commonly used language. Conclusions: Generally, RCTs are found in publications concentrating on cardiovascular disease, cancer, asthma, postoperative conditon, health, and anesthetics. Zone analysis and graphical formulation from Bradford's law of scattering shows variations from the standard Bradford model. Forty-two core journals were identified using Bradford's law. PMID:16239941

  6. Religion and body weight: a review of quantitative studies.

    PubMed

    Yeary, Karen Hye-Cheon Kim; Sobal, Jeffery; Wethington, Elaine

    2017-10-01

    Increasing interest in relationships between religion and health has encouraged research about religion and body weight, which has produced mixed findings. We systematically searched 11 bibliographic databases for quantitative studies of religion and weight, locating and coding 85 studies. We conducted a systematic review, analysing descriptive characteristics of the studies as well as relevant religion-body weight associations related to study characteristics. We summarized findings for two categories of religion variables: religious affiliation and religiosity. For religious affiliation, we found evidence for significant associations with body weight in both cross-sectional and longitudinal studies. In particular, Seventh-Day Adventists had lower body weight than other denominations in cross-sectional analyses. For religiosity, significant associations occurred between greater religiosity and higher body weight in both cross-sectional and longitudinal studies. In particular, greater religiosity was significantly associated with higher body weight in bivariate analyses but less so in multivariate analyses. A greater proportion of studies that used a representative sample, longitudinal analyses, and samples with only men reported significant associations between religiosity and weight. Evidence in seven studies suggested that health behaviours and psychosocial factors mediate religion-weight relationships. More longitudinal studies and analyses of mediators are needed to provide stronger evidence and further elucidate religion-weight relationships. © 2017 World Obesity Federation.

  7. A Map of Clinical Dermatology Research Centers in Spain: Results of the MaIND Study.

    PubMed

    Molina-Leyva, A; Descalzo, M A; García-Doval, I

    2017-06-29

    Bibliometric indicators and analyses of clinical research articles can help to quantify the scientific production of hospitals and institutions and identify their main areas of research. The aim of this study was to draw up a bibliometric map of clinical research in dermatology by Spanish hospitals and institutions through an analysis of quantitative, qualitative, and topic-based variables. Bibliometric study of clinical research articles that met the inclusion criteria and had a definitive publication date between 2005 and 2014 in PubMed or Embase in which the corresponding author's affiliation was a Spanish dermatology department or institution. Barcelona and Madrid were the provinces with the highest number of articles and citations. The centers with the most articles and citations were Hospital Clínic and Instituto Valenciano de Oncología. Those 2 hospitals also produced the highest number of articles on the most common research topic identified: melanoma. Because the articles were selected on the basis of the affiliation of the corresponding author to a Spanish dermatology center, this analysis does not include collaborative studies or clinical research studies led by nondermatology centers. We have created a bibliometric map of clinical dermatology research in Spain that shows the distribution of scientific production and the main areas of research by province and hospital/institution. This map could be useful for education and research purposes. Copyright © 2017 AEDV. Publicado por Elsevier España, S.L.U. All rights reserved.

  8. Research on Health Inequalities in Latin America and the Caribbean: Bibliometric Analysis (1971–2000) and Descriptive Content Analysis (1971–1995)

    PubMed Central

    Almeida-Filho, Naomar; Kawachi, Ichiro; Filho, Alberto Pellegrini; Dachs, J. Norberto W.

    2003-01-01

    We conducted a bibliometric and content analysis of research on health inequalities produced in Latin American and Caribbean countries. In our bibliometric analysis (n = 576), we used indexed material published between 1971 and 2000. The content analysis (n = 269) covered the period 1971 to 1995 and included unpublished material. We found recent rapid growth in overall output. Brazil, Chile, and Mexico contributed mostly empirical research, while Ecuador and Argentina produced more conceptual studies. We found, in the literature reviewed, a relative neglect of gender, race, and ethnicity issues. We also found remarkable diversity in research designs, however, along with strong consideration of ecological and ethnographic methods absent in other research traditions. PMID:14652329

  9. Eye neoplasms research: a bibliometric analysis from 1966 to 2012.

    PubMed

    Boudry, Christophe; Mouriaux, Fréderic

    2015-01-01

    To calculate the growth rate of the biomedical literature on eye neoplasms and to assess which journals, countries, and continents are the most productive. PubMed was used to search for articles published from 1966 to 2012. Total number of articles per year was fitted to a linear equation as well as an exponential curve. To identify the core journals and predict the number of journals containing articles related to eye neoplasms, Bradford's law was applied. For each country and each continent, the gross domestic product (GDP) index (publications per $1 billion USD of GDP) and the population index (publications per million inhabitants) were calculated. A total of 27,943 references were retrieved. The growth in the number of publications showed a linear increase with a yearly average growth rate of 2.08%, which was lower than for the whole PubMed database (3.59%). Using Bradford's law, 17 core journals were identified, among which 2 journals produced more than 1000 articles (JAMA Ophthalmology and American Journal of Ophthalmology). Europe was the most productive continent, followed by North America and Asia. The United States was by far the predominant country in number of publications, followed by Germany and the United Kingdom. However, population and GDP indexes showed that absolute production did not reflect the production per capita or economic efficiency. This bibliometric study provides data contributing to a better understanding of the eye neoplasm research field.

  10. Applying microfluidic techniques in quantitative studies of protein aggregation

    NASA Astrophysics Data System (ADS)

    Herling, Therese

    2012-02-01

    Protein aggregation and fibrillation is involved in a number of devastating diseases, of which we have a limited understanding at present. Microfluidic techniques can be used in developing quantitative assays to study individual aspects of protein aggregation. Under certain conditions bovine insulin aggregates to give spherulites; spherical structures with fibrils growing and branching out from a central core. Drawing a parallel to actin polymerisation of the cell's cytoskeleton, fibril growth generates force. The force generated by polymerisation at fibril ends during spherulite growth can be measured in a microfluidic environment (TPJ Knowles et al, PNAS, 2009). By measuring the bending of four polydimethylsiloxane walls by a growing spherulite positioned in the centre, the force generated by polymerisation at fibril termini can be calculated. By growing the spherulites with a constant flow of monomer, the maximum force able to be generated by fibril growth, the stall force, can be calculated. This gives insight into the energy landscape of protein aggregation.

  11. A quantitative study of intracranial hypotensive syndrome by magnetic resonance.

    PubMed

    Tian, Weizhong; Zhang, Ji; Chen, Jinhua; Liu, Ying; Chen, Xiaoyun; Wang, Ning

    2016-02-01

    The study aims to investigate the magnetic resonance imaging (MRI) findings of intracranial hypotension syndrome (IHS) and the change of quantitative indicators, so as to yield a deeper understanding of the disease. The clinical data and MRI findings of 26 cases of IHS which were confirmed by lumbar puncture were retrospectively analyzed. Two physicians evaluated the MRI findings including thickening and enhancement of dural, pituitary enlargement, subdural effusion (hematocele), venous engorgement and brain sagging, and measured the quantitative indicators including mamillopontine distance and pontomesencephalic angle. The consistency between the two results of the physicians was assessed by Kappa consistency test. The differences of mamillopontine distance and pontomesencephalic angle between the patient group and the control group were determined by paired t-test. The diagnostic efficiency of mamillopontine distance and pontomesencephalic angle was assessed by area under the ROC curve, and their best diagnostic thresholds were also determined, respectively. Age- and sex-matched healthy volunteers controls (n=26) were recruited and served as the control group. All of the 26 patients suffered from the characterized by orthostatic headache of IHS. The clinical evaluations of dural thickening and enhancement, pituitary enlargement, subdural effusion (hematocele), venous engorgement by the two physicians showed excellent agreements (κ=0.808, 1 and 0.906, P<0.01), and the clinical evaluations of brain sagging showed medium agreements (κ=0.606, P<0.01). The mamillopontine distance and pontomesencephalic angle of the patient group were 5.4 ± 1.6mm and 47.8 ± 8.7°, respectively, which were obviously less than those of the control group (6.9 ± 1.1mm and 61.0 ± 6.1°, respectively), and the differences were statistically significant (t=-4.563, P<0.01; t=-.329, P<0.01). The area under ROC curve of mamillopontine distance and pontomesencephalic angle were 0.774 and 0

  12. Top 100 cited articles in cardiovascular magnetic resonance: a bibliometric analysis.

    PubMed

    Khan, Muhammad Shahzeb; Ullah, Waqas; Riaz, Irbaz Bin; Bhulani, Nizar; Manning, Warren J; Tridandapani, Srini; Khosa, Faisal

    2016-11-21

    With limited health care resources, bibliometric studies can help guide researchers and research funding agencies towards areas where reallocation or increase in research activity is warranted. Bibliometric analyses have been published in many specialties and sub-specialties but our literature search did not reveal a bibliometric analysis on Cardiovascular Magnetic Resonance (CMR). The main objective of the study was to identify the trends of the top 100 cited articles on CMR research. Web of Science (WOS) search was used to create a database of all English language scientific journals. This search was then cross-referenced with a similar search term query of Scopus® to identify articles that may have been missed on the initial search. Articles were ranked by citation count and screened by two independent reviewers. Citations for the top 100 articles ranged from 178 to 1925 with a median of 319.5. Only 17 articles were cited more than 500 times, and the vast majority (n = 72) were cited between 200-499 times. More than half of the articles (n = 52) were from the United States of America, and more than one quarter (n = 21) from the United Kingdom. More than four fifth (n = 86) of the articles were published between the time period 2000-2014 with only 1 article published before 1990. Circulation and Journal of the American College of Cardiology made up more than half (n = 62) of the list. We found 10 authors who had greater than 5 publications in the list. Our study provides an insight on the characteristics and quality of the most highly cited CMR literature, and a list of the most influential references related to CMR.

  13. [Bibliometric map of Spain 1996-2004: biomedicine and health sciences].

    PubMed

    Méndez-Vásquez, Raúl Isaac; Suñén-Pinyol, Eduard; Cervelló, Rosa; Camí, Jordi

    2008-03-01

    The study presents the bibliometric analysis of the Spanish scientific output in biomedicine during 1996-2004. This is the last edition of a series of bibliometric studies aimed to characterize the Spanish scientific performance in biomedicine. The analysis was restricted to citable documents for which simple and composite bibliometric indicators were obtained at different aggregation levels: fields, autonomous regions, institutional sectors and research centres. The documents were selected according to the Journal Citation Reports, and were assigned to affiliation centres following an integer counting scheme after an exhaustive normalization of the affiliation addresses. Compared to the period 1994-2002, research activity in biomedicine grew as much as Spain: 8.9% in the number of documents; 22.5% citations; 12.5% citation per document average and 27.2% international cooperation. Besides, biomedicine showed the highest citation per document average compared to other major fields. International cooperation in biomedicine (27.2%) reached the European average. The documents published in international cooperation account for the half of citations to documents in biomedicine. The number of documents and citations belonging to the clinic medicine subfield and to the health sector showed the highest growth. In general, these results reproduce the tendencies described in prior studies. The documents in biomedicine showed a highly asymmetric distribution among institutional sectors, autonomous regions, scientific fields and research centres. The remarkably increase in the output of clinical medicine field and in the health sector could be the consequence of important science policy actions undertaken in these areas in the last years.

  14. Mapping the field: a bibliometric analysis of the research utilization literature in nursing.

    PubMed

    Estabrooks, Carole A; Winther, Connie; Derksen, Linda

    2004-01-01

    Research utilization is the use of research to guide clinical practice. However, little is known about the characteristics of the research utilization literature in nursing, including the development and organization of this field of study. This article addresses the knowledge gap in this field of study by bibliometrically analyzing the research utilization literature in nursing. To map research utilization as a field of study in nursing using bibliometric methods, and to identify the structure of this scientific community, including the current network of researchers. A search of electronic and hard copy databases resulted in bibliographic data for 630 articles on research utilization in nursing published between 1972 and 2001. Bibliometric techniques used included a statistical analysis of publication counts, co-word analysis, and co-citation analysis. The analyses showed a trend of increased productivity since the early 1990s. Most publications were authored by a single author, with no tendency toward increased collaboration over time. Most references cited in the articles were nursing references, indicating that there is very little flow into nursing from other fields. Only 4% of the references cited were actual research articles about research utilization, consistent with applied fields in which clinicians most commonly cite other clinicians. The 630 articles were published in a total of 194 different journals, with the Journal of Advanced Nursing identified as a key journal in the field. According to the analysis, tremendous growth has occurred in the field of research utilization. However, the limited amount of collaborative research and the repeated citation of a few references indicate that the field is under-developed. The research utilization field would benefit from more substantive conceptual and empirical work, and more collaboration among emerging scholars.

  15. A study on the quantitative evaluation of skin barrier function

    NASA Astrophysics Data System (ADS)

    Maruyama, Tomomi; Kabetani, Yasuhiro; Kido, Michiko; Yamada, Kenji; Oikaze, Hirotoshi; Takechi, Yohei; Furuta, Tomotaka; Ishii, Shoichi; Katayama, Haruna; Jeong, Hieyong; Ohno, Yuko

    2015-03-01

    We propose a quantitative evaluation method of skin barrier function using Optical Coherence Microscopy system (OCM system) with coherency of near-infrared light. There are a lot of skin problems such as itching, irritation and so on. It has been recognized skin problems are caused by impairment of skin barrier function, which prevents damage from various external stimuli and loss of water. To evaluate skin barrier function, it is a common strategy that they observe skin surface and ask patients about their skin condition. The methods are subjective judgements and they are influenced by difference of experience of persons. Furthermore, microscopy has been used to observe inner structure of the skin in detail, and in vitro measurements like microscopy requires tissue sampling. On the other hand, it is necessary to assess objectively skin barrier function by quantitative evaluation method. In addition, non-invasive and nondestructive measuring method and examination changes over time are needed. Therefore, in vivo measurements are crucial for evaluating skin barrier function. In this study, we evaluate changes of stratum corneum structure which is important for evaluating skin barrier function by comparing water-penetrated skin with normal skin using a system with coherency of near-infrared light. Proposed method can obtain in vivo 3D images of inner structure of body tissue, which is non-invasive and non-destructive measuring method. We formulate changes of skin ultrastructure after water penetration. Finally, we evaluate the limit of performance of the OCM system in this work in order to discuss how to improve the OCM system.

  16. Quantitative sonographic image analysis for hepatic nodules: a pilot study.

    PubMed

    Matsumoto, Naoki; Ogawa, Masahiro; Takayasu, Kentaro; Hirayama, Midori; Miura, Takao; Shiozawa, Katsuhiko; Abe, Masahisa; Nakagawara, Hiroshi; Moriyama, Mitsuhiko; Udagawa, Seiichi

    2015-10-01

    The aim of this study was to investigate the feasibility of quantitative image analysis to differentiate hepatic nodules on gray-scale sonographic images. We retrospectively evaluated 35 nodules from 31 patients with hepatocellular carcinoma (HCC), 60 nodules from 58 patients with liver hemangioma, and 22 nodules from 22 patients with liver metastasis. Gray-scale sonographic images were evaluated with subjective judgment and image analysis using ImageJ software. Reviewers classified the shape of nodules as irregular or round, and the surface of nodules as rough or smooth. Circularity values were lower in the irregular group than in the round group (median 0.823, 0.892; range 0.641-0.915, 0.784-0.932, respectively; P = 3.21 × 10(-10)). Solidity values were lower in the rough group than in the smooth group (median 0.957, 0.968; range 0.894-0.986, 0.933-0.988, respectively; P = 1.53 × 10(-4)). The HCC group had higher circularity and solidity values than the hemangioma group. The HCC and liver metastasis groups had lower median, mean, modal, and minimum gray values than the hemangioma group. Multivariate analysis showed circularity [standardized odds ratio (OR), 2.077; 95 % confidential interval (CI) = 1.295-3.331; P = 0.002] and minimum gray value (OR 0.482; 95 % CI = 0.956-0.990; P = 0.001) as factors predictive of malignancy. The combination of subjective judgment and image analysis provided 58.3 % sensitivity and 89.5 % specificity with AUC = 0.739, representing an improvement over subjective judgment alone (68.4 % sensitivity, 75.0 % specificity, AUC = 0.701) (P = 0.008). Quantitative image analysis for ultrasonic images of hepatic nodules may correlate with subjective judgment in predicting malignancy.

  17. Motor events during healthy sleep: a quantitative polysomnographic study.

    PubMed

    Frauscher, Birgit; Gabelia, David; Mitterling, Thomas; Biermayr, Marlene; Bregler, Deborah; Ehrmann, Laura; Ulmer, Hanno; Högl, Birgit

    2014-04-01

    Many sleep disorders are characterized by increased motor activity during sleep. In contrast, studies on motor activity during physiological sleep are largely lacking. We quantitatively investigated a large range of motor phenomena during polysomnography in physiological sleep. Prospective polysomnographic investigation. Academic referral sleep laboratory. One hundred healthy sleepers age 19-77 y were strictly selected from a representative population sample by a two-step screening procedure. N/A. Polysomnography according to American Academy of Sleep Medicine (AASM) standards was performed, and quantitative normative values were established for periodic limb movements in sleep (PLMS), high frequency leg movements (HFLM), fragmentary myoclonus (FM), neck myoclonus (NM), and rapid eye movement (REM)-related electromyographic (EMG) activity. Thirty-six subjects had a PLMS index > 5/h, 18 had a PLMS index > 15/h (90th percentile: 24.8/h). Thirty-three subjects had HFLM (90th percentile: four sequences/night). All subjects had FM (90th percentile 143.7/h sleep). Nine subjects fulfilled AASM criteria for excessive FM. Thirty-five subjects had NM (90th percentile: 8.8/h REM sleep). For REM sleep, different EMG activity measures for the mentalis and flexor digitorum superficialis muscles were calculated: the 90th percentile for phasic mentalis EMG activity for 30-sec epochs according to AASM recommendation was 15.6%, and for tonic mentalis EMG activity 2.6%. Twenty-five subjects exceeded the recently proposed phasic mentalis cutoff of 11%. None of the subjects exceeded the tonic mentalis cutoff of 9.6%. Quantification of motor phenomena is a basic prerequisite to develop normative values, and is a first step toward a more precise description of the various motor phenomena present during sleep. Because rates of motor events were unexpectedly high even in physiological sleep, the future use of normative values for both research and clinical routine is essential.

  18. ABRF-PRG07: advanced quantitative proteomics study.

    PubMed

    Falick, Arnold M; Lane, William S; Lilley, Kathryn S; MacCoss, Michael J; Phinney, Brett S; Sherman, Nicholas E; Weintraub, Susan T; Witkowska, H Ewa; Yates, Nathan A

    2011-04-01

    A major challenge for core facilities is determining quantitative protein differences across complex biological samples. Although there are numerous techniques in the literature for relative and absolute protein quantification, the majority is nonroutine and can be challenging to carry out effectively. There are few studies comparing these technologies in terms of their reproducibility, accuracy, and precision, and no studies to date deal with performance across multiple laboratories with varied levels of expertise. Here, we describe an Association of Biomolecular Resource Facilities (ABRF) Proteomics Research Group (PRG) study based on samples composed of a complex protein mixture into which 12 known proteins were added at varying but defined ratios. All of the proteins were present at the same concentration in each of three tubes that were provided. The primary goal of this study was to allow each laboratory to evaluate its capabilities and approaches with regard to: detection and identification of proteins spiked into samples that also contain complex mixtures of background proteins and determination of relative quantities of the spiked proteins. The results returned by 43 participants were compiled by the PRG, which also collected information about the strategies used to assess overall performance and as an aid to development of optimized protocols for the methodologies used. The most accurate results were generally reported by the most experienced laboratories. Among laboratories that used the same technique, values that were closer to the expected ratio were obtained by more experienced groups.

  19. ABRF-PRG07: Advanced Quantitative Proteomics Study

    PubMed Central

    Falick, Arnold M.; Lane, William S.; Lilley, Kathryn S.; MacCoss, Michael J.; Phinney, Brett S.; Sherman, Nicholas E.; Weintraub, Susan T.; Witkowska, H. Ewa; Yates, Nathan A.

    2011-01-01

    A major challenge for core facilities is determining quantitative protein differences across complex biological samples. Although there are numerous techniques in the literature for relative and absolute protein quantification, the majority is nonroutine and can be challenging to carry out effectively. There are few studies comparing these technologies in terms of their reproducibility, accuracy, and precision, and no studies to date deal with performance across multiple laboratories with varied levels of expertise. Here, we describe an Association of Biomolecular Resource Facilities (ABRF) Proteomics Research Group (PRG) study based on samples composed of a complex protein mixture into which 12 known proteins were added at varying but defined ratios. All of the proteins were present at the same concentration in each of three tubes that were provided. The primary goal of this study was to allow each laboratory to evaluate its capabilities and approaches with regard to: detection and identification of proteins spiked into samples that also contain complex mixtures of background proteins and determination of relative quantities of the spiked proteins. The results returned by 43 participants were compiled by the PRG, which also collected information about the strategies used to assess overall performance and as an aid to development of optimized protocols for the methodologies used. The most accurate results were generally reported by the most experienced laboratories. Among laboratories that used the same technique, values that were closer to the expected ratio were obtained by more experienced groups. PMID:21455478

  20. Cancer patients' needs during hospitalisation: a quantitative and qualitative study

    PubMed Central

    Tamburini, Marcello; Gangeri, Laura; Brunelli, Cinzia; Boeri, Paolo; Borreani, Claudia; Bosisio, Marco; Karmann, Claude Fusco; Greco, Margherita; Miccinesi, Guido; Murru, Luciana; Trimigno, Patrizia

    2003-01-01

    Background The evaluation of cancer patients needs, especially during that delicate period when they are hospitalized, allows the identification of those areas of care that require to be improved. Aims of the study were to evaluate the needs in cancer inpatients and to improve the understanding of the meanings of the needs expressed. Methods The study was conducted during a "sample day", with all the cancer patients involved having been hospitalized at the Istituto Nazionale Tumori of Milan (INT) for at least 48 hours beforehand. The study was carried out using quantitative and qualitative methodologies. The quantitative part of the study consisted in making use of the Needs Evaluation Questionnaire (NEQ), a standardized questionnaire administered by the INT Psychology Unit members, supported by a group of volunteers from the Milan section of the Italian League Against Cancer. The aim of the qualitative part of the study, by semi-structured interviews conducted with a small sample of 8 hospitalized patients, was to improve our understanding of the meanings, implications of the needs directly described from the point of view of the patients. Such an approach determines the reasons and conditions of the dissatisfaction in the patient, and provides additional information for the planning of improvement interventions. Results Of the 224 eligible patients, 182 (81%) completed the questionnaire. Four of the top five needs expressed by 40% or more of the responders concerned information needs (diagnosis, future conditions, dialogue with doctors, economic-insurance solutions related to the disease). Only one of the 5 was concerned with improved "hotel" services (bathrooms, meals, cleanliness). Qualitative analysis showed that the most expressed need (to receive more information on their future conditions) has the meaning to know how their future life will be affected more than to know his/her actual prognosis. Conclusions Some of the needs which emerged from this

  1. Quantitative structure activity relationship studies of mushroom tyrosinase inhibitors

    NASA Astrophysics Data System (ADS)

    Xue, Chao-Bin; Luo, Wan-Chun; Ding, Qi; Liu, Shou-Zhu; Gao, Xing-Xiang

    2008-05-01

    Here, we report our results from quantitative structure-activity relationship studies on tyrosinase inhibitors. Interactions between benzoic acid derivatives and tyrosinase active sites were also studied using a molecular docking method. These studies indicated that one possible mechanism for the interaction between benzoic acid derivatives and the tyrosinase active site is the formation of a hydrogen-bond between the hydroxyl (aOH) and carbonyl oxygen atoms of Tyr98, which stabilized the position of Tyr98 and prevented Tyr98 from participating in the interaction between tyrosinase and ORF378. Tyrosinase, also known as phenoloxidase, is a key enzyme in animals, plants and insects that is responsible for catalyzing the hydroxylation of tyrosine into o-diphenols and the oxidation of o-diphenols into o-quinones. In the present study, the bioactivities of 48 derivatives of benzaldehyde, benzoic acid, and cinnamic acid compounds were used to construct three-dimensional quantitative structure-activity relationship (3D-QSAR) models using comparative molecular field (CoMFA) and comparative molecular similarity indices (CoMSIA) analyses. After superimposition using common substructure-based alignments, robust and predictive 3D-QSAR models were obtained from CoMFA ( q 2 = 0.855, r 2 = 0.978) and CoMSIA ( q 2 = 0.841, r 2 = 0.946), with 6 optimum components. Chemical descriptors, including electronic (Hammett σ), hydrophobic (π), and steric (MR) parameters, hydrogen bond acceptor (H-acc), and indicator variable ( I), were used to construct a 2D-QSAR model. The results of this QSAR indicated that π, MR, and H-acc account for 34.9, 31.6, and 26.7% of the calculated biological variance, respectively. The molecular interactions between ligand and target were studied using a flexible docking method (FlexX). The best scored candidates were docked flexibly, and the interaction between the benzoic acid derivatives and the tyrosinase active site was elucidated in detail. We believe

  2. Quantitative studies of human urinary excretion of uropontin.

    PubMed

    Min, W; Shiraga, H; Chalko, C; Goldfarb, S; Krishna, G G; Hoyer, J R

    1998-01-01

    Uropontin is the urinary form of osteopontin, an aspartic acid-rich phosphorylated glycoprotein. Uropontin has been previously shown to be a potent inhibitor of the nucleation, growth and aggregation of calcium oxalate crystals and the binding of these crystals to renal epithelial cells. Quantitative data defining the excretion of this protein are necessary to determine its role in urinary stone formation. In the present studies, we determined uropontin excretion rates of normal humans. Urine samples were obtained under conditions of known dietary intake from young adult human volunteers with no history, radiographic or laboratory evidence of renal disease. Urinary concentrations of uropontin were measured by a sensitive ELISA employing an affinity purified polyclonal antiserum to uropontin. Thirteen normal subjects ingested a constant diet providing 1 gram of calcium, 1 gram of phosphorus, 150 mEq of sodium and 1 gram of protein per kilogram of body wt per day during an eight day study period. The relationship of urinary volume to uropontin excretion was assessed by varying fluid intake on the last four days of the study to change the mean urine volume/24 hr by > 500 ml. Urine collected in six hour aliquots for eight days was analyzed for uropontin by ELISA, and for calcium, and creatinine. Daily uropontin excretion of 13 individual subjects was 3805 +/- 1805 micrograms/24 hr (mean +/- 1 SD). The mean urinary levels (1.9 micrograms/ml) detected in the present study are sufficient for inhibition of crystallization; our previous studies have demonstrated that the nucleation, growth and aggregation of calcium oxalate crystals and their binding to renal cells in vitro are inhibited by this concentration of purified uropontin. In contrast to the regular pattern of diurnal variation of calcium excretion seen in most subjects, uropontin excretion showed no regularity of diurnal variation and was not directly related to either calcium or creatinine excretion or changes in

  3. A Quantitative Study of Oxygen as a Metabolic Regulator

    NASA Technical Reports Server (NTRS)

    Radhakrishnan, Krishnan; LaManna, Joseph C.; Cabrera, Marco E.

    1999-01-01

    An acute reduction in oxygen (O2) delivery to a tissue is generally associated with a decrease in phosphocreatine, increases in ADP, NADH/NAD, and inorganic phosphate, increased rates of glycolysis and lactate production, and reduced rates of pyruvate and fatty acid oxidation. However, given the complexity of the human bioenergetic system and its components, it is difficult to determine quantitatively how cellular metabolic processes interact to maintain ATP homeostasis during stress (e.g., hypoxia, ischemia, and exercise). Of special interest is the determination of mechanisms relating tissue oxygenation to observed metabolic responses at the tissue, organ, and whole body levels and the quantification of how changes in tissue O2 availability affect the pathways of ATP synthesis and the metabolites that control these pathways. In this study, we extend a previously developed mathematical model of human bioenergetics to provide a physicochemical framework that permits quantitative understanding of O2 as a metabolic regulator. Specifically, the enhancement permits studying the effects of variations in tissue oxygenation and in parameters controlling the rate of cellular respiration on glycolysis, lactate production, and pyruvate oxidation. The whole body is described as a bioenergetic system consisting of metabolically distinct tissue/organ subsystems that exchange materials with the blood. In order to study the dynamic response of each subsystem to stimuli, we solve the ordinary differential equations describing the temporal evolution of metabolite levels, given the initial concentrations. The solver used in the present study is the packaged code LSODE, as implemented in the NASA Lewis kinetics and sensitivity analysis code, LSENS. A major advantage of LSENS is the efficient procedures supporting systematic sensitivity analysis, which provides the basic methods for studying parameter sensitivities (i.e., changes in model behavior due to parameter variation

  4. A descriptive and historical review of bibliometrics with applications to medical sciences.

    PubMed

    Thompson, Dennis F; Walker, Cheri K

    2015-06-01

    The discipline of bibliometrics involves the application of mathematical and statistical methods to scholarly publications. The first attempts at systematic data collection were provided by Alfred Lotka and Samuel Bradford, who subsequently established the foundational laws of bibliometrics. Eugene Garfield ushered in the modern era of bibliometrics with the routine use of citation analysis and systematized processing. Key elements of bibliometric analysis include database coverage, consistency and accuracy of the data, data fields, search options, and analysis and use of metrics. A number of bibliometric applications are currently being used in medical science and health care. Bibliometric parameters and indexes may be increasingly used by grant funding sources as measures of research success. Universities may build benchmarking standards from bibliometric data to determine academic achievement through promotion and tenure guidelines in the future. This article reviews the history, definition, laws, and elements of bibliometric principles and provides examples of bibliometric applications to the broader health care community. To accomplish this, the Medline (1966-2014) and Web of Science (1945-2014) databases were searched to identify relevant articles; select articles were also cross-referenced. Articles selected were those that provided background, history, descriptive analysis, and application of bibliometric principles and metrics to medical science and health care. No attempt was made to cover all areas exhaustively; rather, key articles were chosen that illustrate bibliometric concepts and enhance the reader's knowledge. It is important that faculty and researchers understand the limitations and appropriate uses of bibliometric data. Bibliometrics has considerable potential as a research area for health care scientists and practitioners that can be used to discover new information about academic trends, pharmacotherapy, disease, and broader health sciences

  5. A historical review and bibliometric analysis of research on estuary pollution.

    PubMed

    Sun, Jinshui; Wang, Ming-Huang; Ho, Yuh-Shan

    2012-01-01

    A bibliometric method based on Science Citation Index-Expanded published by the Thomson Reuters was used to quantitatively assess the global estuary pollution research from 1991 to 2010. The main results were as follows: there had been a notable growth trend in publication outputs. Marine Pollution Bulletin was the most active journal. Environmental sciences were top popular subject categories. USA produced the most single, internationally collaborative, first authored and corresponding authored articles. The Chinese Academy of Sciences was the most productive institute for the total articles. Sediment was the most active research topic, which ranked 1st in article title, article abstract, author keyword, and KeyWords Plus analysis, respectively. Heavy metals received stable focus on a high degree in the field of estuary pollution research. Mostly refractory organic compounds (e.g. PAHs) became more active. Biomarkers and bioaccumulation both were active issues. Eutrophication of estuarine waters receives increasing concern in estuary pollution research.

  6. Bibliometric indices: defining academic productivity and citation rates of researchers, departments and journals.

    PubMed

    Garner, Rebecca M; Hirsch, Joshua A; Albuquerque, Felipe C; Fargen, Kyle M

    2017-08-20

    There has been an increasing focus on academic productivity for the purposes of promotion and funding within departments and institutions but also for comparison of individuals, institutions, specialties, and journals. A number of quantitative indices are used to investigate and compare academic productivity. These include various calculations attempting to analyze the number and citations of publications in order to capture both the quality and quantity of publications, such as the h index, the e index, impact factor, and Eigenfactor score. The indices have varying advantages and limitations and thus a basic knowledge is required in order to understand their potential utility within academic medicine. This article describes the various bibliometric indices and discusses recent applications of these metrics within the neurological sciences. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  7. Hypersonic and Supersonic Flow Roadmaps Using Bibliometrics and Database Tomography.

    ERIC Educational Resources Information Center

    Kostoff, R. N.; Eberhart, Henry J.; Toothman, Darrell Ray

    1999-01-01

    Database Tomography (DT) is a textual database-analysis system consisting of algorithms for extracting multiword phrase frequencies and proximities from a large textual database, to augment interpretative capabilities of the expert human analyst. Describes use of the DT process, supplemented by literature bibliometric analyses, to derive technical…

  8. "Library Quarterly," 1956-2004: An Exploratory Bibliometric Analysis

    ERIC Educational Resources Information Center

    Young, Arthur P.

    2006-01-01

    "Library Quarterly's" seventy-fifth anniversary invites an analysis of the journal's bibliometric dimension, including contributor attributes, various author rankings, and citation impact. Eugene Garfield's HistCite software, linked to Thomson Scientific's Web of Science, as made available by Garfield, for the period 1956-2004, was used as the…

  9. Hypersonic and Supersonic Flow Roadmaps Using Bibliometrics and Database Tomography.

    ERIC Educational Resources Information Center

    Kostoff, R. N.; Eberhart, Henry J.; Toothman, Darrell Ray

    1999-01-01

    Database Tomography (DT) is a textual database-analysis system consisting of algorithms for extracting multiword phrase frequencies and proximities from a large textual database, to augment interpretative capabilities of the expert human analyst. Describes use of the DT process, supplemented by literature bibliometric analyses, to derive technical…

  10. A Bibliography of Bibliometrics and Citation Indexing and Analysis.

    ERIC Educational Resources Information Center

    Hjerppe, Roland

    More than 2,000 documents about citations, citation analysis, citation indexes, and bibliometrics are cited in this bibliography. Some documents on communication in science, scientometrics, the science of science, and information retrieval have been included where they apply to citation indexing. Although most of the documents cited are in…

  11. Quantitative thermophoretic study of disease-related protein aggregates.

    PubMed

    Wolff, Manuel; Mittag, Judith J; Herling, Therese W; Genst, Erwin De; Dobson, Christopher M; Knowles, Tuomas P J; Braun, Dieter; Buell, Alexander K

    2016-03-17

    Amyloid fibrils are a hallmark of a range of neurodegenerative disorders, including Alzheimer's and Parkinson's diseases. A detailed understanding of the physico-chemical properties of the different aggregated forms of proteins, and of their interactions with other compounds of diagnostic or therapeutic interest, is crucial for devising effective strategies against such diseases. Protein aggregates are situated at the boundary between soluble and insoluble structures, and are challenging to study because classical biophysical techniques, such as scattering, spectroscopic and calorimetric methods, are not well adapted for their study. Here we present a detailed characterization of the thermophoretic behavior of different forms of the protein α-synuclein, whose aggregation is associated with Parkinson's disease. Thermophoresis is the directed net diffusional flux of molecules and colloidal particles in a temperature gradient. Because of their low volume requirements and rapidity, analytical methods based on this effect have considerable potential for high throughput screening for drug discovery. In this paper we rationalize and describe in quantitative terms the thermophoretic behavior of monomeric, oligomeric and fibrillar forms of α-synuclein. Furthermore, we demonstrate that microscale thermophoresis (MST) is a valuable method for screening for ligands and binding partners of even such highly challenging samples as supramolecular protein aggregates.

  12. Quantitative study of developmental biology confirms Dickinsonia as a metazoan.

    PubMed

    Hoekzema, Renee S; Brasier, Martin D; Dunn, Frances S; Liu, Alexander G

    2017-09-13

    The late Ediacaran soft-bodied macroorganism Dickinsonia (age range approx. 560-550 Ma) has often been interpreted as an early animal, and is increasingly invoked in debate on the evolutionary assembly of eumetazoan body plans. However, conclusive positive evidence in support of such a phylogenetic affinity has not been forthcoming. Here we subject a collection of Dickinsonia specimens interpreted to represent multiple ontogenetic stages to a novel, quantitative method for studying growth and development in organisms with an iterative body plan. Our study demonstrates that Dickinsonia grew via pre-terminal 'deltoidal' insertion and inflation of constructional units, followed by a later inflation-dominated phase of growth. This growth model is contrary to the widely held assumption that Dickinsonia grew via terminal addition of units at the end of the organism bearing the smallest units. When considered alongside morphological and behavioural attributes, our developmental data phylogenetically constrain Dickinsonia to the Metazoa, specifically the Eumetazoa plus Placozoa total group. Our findings have implications for the use of Dickinsonia in developmental debates surrounding the metazoan acquisition of axis specification and metamerism. © 2017 The Author(s).

  13. Quantitative thermophoretic study of disease-related protein aggregates

    PubMed Central

    Wolff , Manuel; Mittag, Judith J.; Herling, Therese W.; Genst, Erwin De; Dobson, Christopher M.; Knowles, Tuomas P. J.; Braun, Dieter; Buell, Alexander K.

    2016-01-01

    Amyloid fibrils are a hallmark of a range of neurodegenerative disorders, including Alzheimer’s and Parkinson’s diseases. A detailed understanding of the physico-chemical properties of the different aggregated forms of proteins, and of their interactions with other compounds of diagnostic or therapeutic interest, is crucial for devising effective strategies against such diseases. Protein aggregates are situated at the boundary between soluble and insoluble structures, and are challenging to study because classical biophysical techniques, such as scattering, spectroscopic and calorimetric methods, are not well adapted for their study. Here we present a detailed characterization of the thermophoretic behavior of different forms of the protein α-synuclein, whose aggregation is associated with Parkinson’s disease. Thermophoresis is the directed net diffusional flux of molecules and colloidal particles in a temperature gradient. Because of their low volume requirements and rapidity, analytical methods based on this effect have considerable potential for high throughput screening for drug discovery. In this paper we rationalize and describe in quantitative terms the thermophoretic behavior of monomeric, oligomeric and fibrillar forms of α-synuclein. Furthermore, we demonstrate that microscale thermophoresis (MST) is a valuable method for screening for ligands and binding partners of even such highly challenging samples as supramolecular protein aggregates. PMID:26984748

  14. Thermal quantitative sensory testing: a study of 101 control subjects.

    PubMed

    Hafner, Jessica; Lee, Geoffrey; Joester, Jenna; Lynch, Mary; Barnes, Elizabeth H; Wrigley, Paul J; Ng, Karl

    2015-03-01

    Quantitative sensory testing is useful for the diagnosis, confirmation and monitoring of small fibre neuropathies. Normative data have been reported but differences in methodology, lack of age-specific values and graphical presentation of data make much of these data difficult to apply in a clinical setting. We have collected normative age-specific thermal threshold data for use in a clinical setting and clarified other factors influencing reference values, including the individual machine or operator. Thermal threshold studies were performed on 101 healthy volunteers (21-70 years old) using one of two Medoc Thermal Sensory Analyser II machines (Medoc, Ramat Yishai, Israel) with a number of operators. A further study was performed on 10 healthy volunteers using both machines and one operator at least 3 weeks apart. Thermal threshold detection increases with age and is different for different body regions. There is no significant difference seen in results between machines of the same make and model; however, different operators may influence results. Normative data for thermal thresholds should be applied using only age- and region-specific values and all operators should be trained and strictly adhere to standard protocols. To our knowledge, this is the largest published collection of normal controls for thermal threshold testing presented with regression data which can easily be used in the clinical setting. Crown Copyright © 2014. Published by Elsevier Ltd. All rights reserved.

  15. Application study of transport intensity equation in quantitative phase reconstruction

    NASA Astrophysics Data System (ADS)

    Song, Xiaojun; Cheng, Wei; Wei, Chunjuan; Xue, Liang; Liu, Weijing; Bai, Baodan; Chu, Fenghong

    2016-10-01

    In order to improve detection speed and accuracy of biological cells, a quantitative non-interference optical phase recovery method is proposed in commercial microscope, taking the red blood cells as the classical phase objects. Three bright field micrographs were collected in the experiment. Utilizing the transport intensity equation (TIE), the quantitative phase distributions of red blood cell are gained and agree well with the previous optical phase models. Analysis shows that the resolution of introduced system reaches sub-micron. This method not only quickly gives quantitative phase distribution of cells, but also measures a large number of cells simultaneously. So it is potential in the use of real-time observing and quantitative analyzing of cells in vivo.

  16. A quantitative electroencephalographic study of meditation and binaural beat entrainment.

    PubMed

    Lavallee, Christina F; Koren, Stanley A; Persinger, Michael A

    2011-04-01

    The study objective was to determine the quantitative electroencephalographic correlates of meditation, as well as the effects of hindering (15 Hz) and facilitative (7 Hz) binaural beats on the meditative process. The study was a mixed design, with experience of the subject as the primary between-subject measure and power of the six classic frequency bands (δ, θ, low α, high α, β, γ), neocortical lobe (frontal, temporal, parietal, occipital), hemisphere (left, right), and condition (meditation only, meditation with 7-Hz beats, meditation with 15-Hz beats) as the within-subject measures. The study was conducted at Laurentian University in Sudbury, Ontario, Canada. The subjects comprised novice (mean of 8 months experience) and experienced (mean of 18 years experience) meditators recruited from local meditation groups. Experimental manipulation included application of hindering and facilitative binaural beats to the meditative process. Experienced meditators displayed increased left temporal lobe δ power when the facilitative binaural beats were applied, whereas the effect was not observed for the novice subjects in this condition. When the hindering binaural beats were introduced, the novice subjects consistently displayed more γ power than the experienced subjects over the course of their meditation, relative to baseline. Based on the results of this study, novice meditators were not able to maintain certain levels of θ power in the occipital regions when hindering binaural beats were presented, whereas when the facilitative binaural beats were presented, the experienced meditators displayed increased θ power in the left temporal lobe. These results suggest that the experienced meditators have developed techniques over the course of their meditation practice to counter hindering environmental stimuli, whereas the novice meditators have not yet developed those techniques.

  17. How international is bioethics? A quantitative retrospective study.

    PubMed

    Borry, Pascal; Schotsmans, Paul; Dierickx, Kris

    2006-01-13

    Studying the contribution of individual countries to leading journals in a specific discipline can highlight which countries have the most impact on that discipline and whether a geographic bias exists. This article aims to examine the international distribution of publications in the field of bioethics. Retrospective quantitative study of nine peer reviewed journals in the field of bioethics and medical ethics (Bioethics, Cambridge Quarterly of Healthcare Ethics, Hastings Center Report, Journal of Clinical Ethics, Journal of Medical Ethics, Kennedy Institute of Ethics Journal, Nursing Ethics, Christian Bioethics, and Theoretical Medicine and Bioethics). In total, 4,029 articles published between 1990 and 2003 were retrieved from the nine bioethical journals under study. The United States (59.3%, n = 2390), the United Kingdom (13.5%, n = 544), Canada (4%, n = 160) and Australia (3.8%, n = 154) had the highest number of publications in terms of absolute number of publications. When normalized to population size, smaller affluent countries, such as New Zealand, Finland and Sweden were more productive than the United States. The number of studies originating from the USA was decreasing in the period between 1990 and 2003. While a lot of peer reviewed journals in the field of bioethics profile themselves as international journals, they certainly do not live up to what one would expect from an "international" journal. The fact that English speaking countries, and to a larger extent American authors, dominate the international journals in the field of bioethics is a clear geographic bias towards the bioethical discussions that are going on in these journals.

  18. How international is bioethics? A quantitative retrospective study

    PubMed Central

    2006-01-01

    Background Studying the contribution of individual countries to leading journals in a specific discipline can highlight which countries have the most impact on that discipline and whether a geographic bias exists. This article aims to examine the international distribution of publications in the field of bioethics. Methods Retrospective quantitative study of nine peer reviewed journals in the field of bioethics and medical ethics (Bioethics, Cambridge Quarterly of Healthcare Ethics, Hastings Center Report, Journal of Clinical Ethics, Journal of Medical Ethics, Kennedy Institute of Ethics Journal, Nursing Ethics, Christian Bioethics, and Theoretical Medicine and Bioethics). Results In total, 4,029 articles published between 1990 and 2003 were retrieved from the nine bioethical journals under study. The United States (59.3%, n = 2390), the United Kingdom (13.5%, n = 544), Canada (4%, n = 160) and Australia (3.8%, n = 154) had the highest number of publications in terms of absolute number of publications. When normalized to population size, smaller affluent countries, such as New Zealand, Finland and Sweden were more productive than the United States. The number of studies originating from the USA was decreasing in the period between 1990 and 2003. Conclusion While a lot of peer reviewed journals in the field of bioethics profile themselves as international journals, they certainly do not live up to what one would expect from an "international" journal. The fact that English speaking countries, and to a larger extent American authors, dominate the international journals in the field of bioethics is a clear geographic bias towards the bioethical discussions that are going on in these journals. PMID:16412229

  19. The Evolution of Recent Research on Catalan Literature through the Production of PhD Theses: A Bibliometric and Social Network Analysis

    ERIC Educational Resources Information Center

    Ardanuy, Jordi; Urbano, Cristobal; Quintana, Lluis

    2009-01-01

    Introduction: This paper studies the situation of research on Catalan literature between 1976 and 2003 by carrying out a bibliometric and social network analysis of PhD theses defended in Spain. It has a dual aim: to present interesting results for the discipline and to demonstrate the methodological efficacy of scientometric tools in the…

  20. A quantitative analysis of cardiac myocyte relaxation: a simulation study.

    PubMed

    Niederer, S A; Hunter, P J; Smith, N P

    2006-03-01

    The determinants of relaxation in cardiac muscle are poorly understood, yet compromised relaxation accompanies various pathologies and impaired pump function. In this study, we develop a model of active contraction to elucidate the relative importance of the [Ca2+]i transient magnitude, the unbinding of Ca2+ from troponin C (TnC), and the length-dependence of tension and Ca2+ sensitivity on relaxation. Using the framework proposed by one of our researchers, we extensively reviewed experimental literature, to quantitatively characterize the binding of Ca2+ to TnC, the kinetics of tropomyosin, the availability of binding sites, and the kinetics of crossbridge binding after perturbations in sarcomere length. Model parameters were determined from multiple experimental results and modalities (skinned and intact preparations) and model results were validated against data from length step, caged Ca2+, isometric twitches, and the half-time to relaxation with increasing sarcomere length experiments. A factorial analysis found that the [Ca2+]i transient and the unbinding of Ca2+ from TnC were the primary determinants of relaxation, with a fivefold greater effect than that of length-dependent maximum tension and twice the effect of tension-dependent binding of Ca2+ to TnC and length-dependent Ca2+ sensitivity. The affects of the [Ca2+]i transient and the unbinding rate of Ca2+ from TnC were tightly coupled with the effect of increasing either factor, depending on the reference [Ca2+]i transient and unbinding rate.

  1. Quantitative methods to study epithelial morphogenesis and polarity.

    PubMed

    Aigouy, B; Collinet, C; Merkel, M; Sagner, A

    2017-01-01

    Morphogenesis of an epithelial tissue emerges from the behavior of its constituent cells, including changes in shape, rearrangements, and divisions. In many instances the directionality of these cellular events is controlled by the polarized distribution of specific molecular components. In recent years, our understanding of morphogenesis and polarity highly benefited from advances in genetics, microscopy, and image analysis. They now make it possible to measure cellular dynamics and polarity with unprecedented precision for entire tissues throughout their development. Here we review recent approaches to visualize and measure cell polarity and tissue morphogenesis. The chapter is organized like an experiment. We first discuss the choice of cell and polarity reporters and describe the use of mosaics to reveal hidden cell polarities or local morphogenetic events. Then, we outline application-specific advantages and disadvantages of different microscopy techniques and image projection algorithms. Next, we present methods to extract cell outlines to measure cell polarity and detect cellular events underlying morphogenesis. Finally, we bridge scales by presenting approaches to quantify the specific contribution of each cellular event to global tissue deformation. Taken together, we provide an in-depth description of available tools and theoretical concepts to quantitatively study cell polarity and tissue morphogenesis over multiple scales.

  2. The Evolution of Solar Flux: Quantitative Estimates for Planetary Studies

    NASA Astrophysics Data System (ADS)

    Claire, M.; Sheets, J.; Cohen, M.; Ribas, I.; Meadows, V. S.; Catling, D. C.

    2012-12-01

    The Sun has a profound impact on planetary atmospheres, driving such diverse processes as the vertical temperature profile, molecular reaction rates, and atmospheric escape. Understanding the time-dependence of the solar flux is therefore essential to understanding atmospheric evolution of planets and satellites in the solar system. We present numerical models of the solar flux applicable temporally and spatially throughout the solar system (Claire et al. ApJ, 2012, in press.) We combine data from the Sun and solar analogs to estimate enhanced FUV and Xray continuum and strong line fluxes for the young Sun. In addition, we describe a new parameterization for the near UV, where both the chromosphere and photosphere contribute to the flux, and use Kurucz models to estimate variable visible and infrared fluxes. The modeled fluxes are valid at nanometer resolution from 0.1 nm through the infrared, and from 0.6 Gyr through 6.7 Gyr, with extensions from the solar zero age main sequence to 8.0 Gyr (subject to additional uncertainties). This work enables quantitative estimates of the wavelength dependence of solar flux for a range of paleodates that are relevant to studies of the chemical evolution of planetary atmospheres in the solar system (or around other G-type stars). We apply this parameterization to an early Earth photochemical model, which reveals changes in photolysis reaction rates significant larger than the intrinsic model uncertainties.

  3. Good death in cancer care: a nationwide quantitative study.

    PubMed

    Miyashita, M; Sanjo, M; Morita, T; Hirai, K; Uchitomi, Y

    2007-06-01

    The aims of this study were to (i) conceptualize dimensions of a good death in Japanese cancer care, (ii) clarify the relative importance of each component of a good death and (iii) explore factors related to an individual's perception of the domains of a good death. The general population was sampled using a stratified random sampling method (n = 2548; response rate, 51%) and bereaved families from 12 certified palliative care units were surveyed as well (n = 513; 70%). We asked the subjects about the relative importance of 57 components of a good death. Explanatory factor analysis demonstrated 18 domains contributing to a good death. Ten domains were classified as 'consistently important domains', including 'physical and psychological comfort', 'dying in a favorite place', 'good relationship with medical staff', 'maintaining hope and pleasure', 'not being a burden to others', 'good relationship with family', 'physical and cognitive control', 'environmental comfort', 'being respected as an individual' and 'life completion'. We quantitatively identified 18 important domains that contribute to a good death in Japanese cancer care. The next step of our work should be to conduct a national survey to identify what is required to achieve a good death.

  4. Doubled Haploids for Studying the Inheritance of Quantitative Characters

    PubMed Central

    Choo, T. M.

    1981-01-01

    By using a doubled-haploid population derived from F2 plants, additive and additive x additive genetic variances, as well as the number of segregating genes, can be estimated. An F2-derived doubled-haploid population may contain almost 50% more of the best recombinant than an F1-derived population. However, the best recombinant occurs in the same frequency in the two populations when there is no linkage between genes. The difference in the frequency of the best recombinant between F2- and F3-derived populations is small. This implies that the doubled-haploid method using F2 plants provides only slightly less opportunity for recombination than the conventional breeding methods of self-pollinating crops. In the absence of additive epistasis, a weighted mean of recombination values can be estimated using an F2-derived population and its parental lines. When additive epistasis is present, it can be estimated from doubled-haploid populations derived from two backcrosses. Studies on the linkage of quantitative characters are needed for determining whether doubled haploids should be produced from F2 or from F1 plants in a breeding program. PMID:7343417

  5. A bibliometric analysis of scientific production in cancer molecular epidemiology.

    PubMed

    Ugolini, Donatella; Puntoni, Riccardo; Perera, Frederica P; Schulte, Paul A; Bonassi, Stefano

    2007-08-01

    The main purpose of this research was to compare the scientific production in the field of cancer molecular epidemiology among countries and to evaluate the publication trend between 1995 and 2004. A bibliometric study was carried out searching the PubMed database with a combined search strategy based on the keywords listed in the medical subject headings and a free text search. Only articles from a representative subset of 92 journals--accounting for 80% of papers identified--were selected for the analysis, and the resulting 13,240 abstracts were manually checked according to a list of basic inclusion criteria. The study evaluated the number of publications and the impact factor (mean and sum), absolute and normalized by country population and gross domestic product. A total of 3,842 citations were finally selected for the analysis. Thirty-seven percent came from the European Union (UK, Germany, Italy, France and Sweden ranking at the top), 31.6% from USA and 9.7% from Japan. The highest mean impact factor was reported for Canada (6.3), USA (5.9), Finland (5.8) and UK (5.2). Finland, Sweden and Israel had the best ratio between scientific production and available resources. 'Genetic polymorphism, glutathione transferase, breast neoplasm, risk factors, case-control studies and polymerase chain reaction' were the most used keywords in each of the subgroups evaluated, although inclusion criteria may have privileged studies dealing with exogenous carcinogens. Cancer molecular epidemiology is an expanding area attracting an increasing interest. The identification of an operative definition is a necessary condition to give to this discipline a unique scientific identity.

  6. Bibliometrics as a Tool for Supporting Prospective R&D Decision-Making in the Health Sciences: Strengths, Weaknesses and Options for Future Development.

    PubMed

    Ismail, Sharif; Nason, Edward; Marjanovic, Sonja; Grant, Jonathan

    2012-01-01

    Bibliometric analysis is an increasingly important part of a broader "toolbox" of evaluation methods available to research and development (R&D) policymakers to support decision-making. In the US, UK and Australia, for example, there is evidence of gradual convergence over the past ten years towards a model of university research assessment and ranking incorporating the use of bibliometric measures. In Britain, the Department of Health (England) has shown growing interest in using bibliometric analysis to support prospective R&D decision-making, and has engaged RAND Europe's expertise in this area through a number of exercises since 2005. These range from the macro-level selection of potentially high impact institutions, to micro-level selection of high impact individuals for the National Institute for Health Research's faculty of researchers. The aim of this study is to create an accessible, "beginner's guide" to bibliometric theory and application in the area of health R&D decision-making. The study also aims to identify future directions and possible next steps in this area, based on RAND Europe's work with the Department of Health to date. It is targeted at a range of audiences, and will be of interest to health and biomedical researchers, as well as R&D decision-makers in the UK and elsewhere. The study was completed with funding support from RAND Europe's Health R&D Policy Research Unit with the Department of Health.

  7. The top 100 papers in dry eye - A bibliometric analysis.

    PubMed

    Schargus, Marc; Kromer, Robert; Druchkiv, Vasily; Frings, Andreas

    2017-09-15

    Citation analysis represents one of the best currently available methods for quantifying the impact of articles. Bibliometric studies list the ''best sellers'' in a single field of interest. The purpose of the present study was to identify and analyze the most frequently cited papers in dry eye research that may be of high interest for researchers and clinicians. We reviewed the database of the Institute for Scientific Information to identify articles published from 1900 to September 2016. All dry eye articles published in 59 ophthalmology journals were identified. The top 100 articles were selected for further analysis of authorship, source journal, number of citations, citation rate, geographic origin, article type, and level of evidence. The 100 most-cited articles were published between 1983 and 2011, with most of them in the 2000s. The number of citations per article ranged from 96 to 610, and was greatest for articles published in the 2000s. Each of these articles was published in one of 15 journals. Most articles represented Level-III evidence, followed by Levels II and I. The present study focusing on dry eye research revealed that 55% of the most-cited articles came from the U.S. and 18% from Japan. Diagnostics and therapy were the areas of focus of most of the clinical articles; 13% of the most cited papers were review articles. This analysis provides researchers and clinicians with a detailed overview on the most cited dry eye papers over the past decades. Copyright © 2017. Published by Elsevier Inc.

  8. Bibliometric assessment of the Latin-American contributions in dengue.

    PubMed

    Vera-Polania, Felipe; Perilla-Gonzalez, Yuliana; Martinez-Pulgarin, Dayron F; Baquero-Rodriguez, Juan D; Munoz-Urbano, Marcela; Lagos-Gallego, Mariana; Lagos-Grisales, Guillermo J; Villegas, Soraya; Rodriguez-Morales, Alfonso J

    2014-01-01

    Despite efforts in prevention and control of dengue, it is still a public health problem in the region. There are estimations of 13 million people affected in the Americas, therefore, it is of outmost importance to research it. An assessment on the Latin- American contributions on dengue was done. Bibliometric study at SCI (1980- 2013), MEDLINE/GOPUBMED (1802-2013), Scopus (1959-2013), SCIELO (2004-2013), LILACS (1980- 2013). Different study types, characterized by years, city/country of origin, journals and more productive authors, by country, cites and H index have been conducted. At SCI, 2598 articles were retrieved (21% of the total). Brazil was found to be the highest contributor (31.2%), then Puerto Rico (12.9%) and Mexico (10.7%). At Scopus, there are 2646 articles (16.7% of the total), 31.2% Brazil, 11.1% Mexico, 9.3% Cuba; the region received 41881 citations, 25.4% from Brazil (H index=45), 14.4% Cuba (H index=35) and 12.88% Puerto Rico (H index=38); 9.1% in Brazil were from Fundação Oswaldo Cruz; 1.6% of Mexico corresponded to Instituto Nacional de Salud Publica, 4.9% of Cuba are from Instituto de Medicina Tropical Pedro Kouri. At Medline, there are 2799 records (33.9% from Brazil). At SciELO there are 825 records (46.6% Brazil). At LILACS, there are 1178 records (46.8% Brazil). Brazil is the best producer in the region. In Puerto Rico and Brazil, there observed the epidemiologic burden of the disease. Scientific production in bibliographical data bases, particularly regional, is low, as compared to the high impact of the disease of in urban zones of the region.

  9. Bibliometrics of NIHR HTA monographs and their related journal articles

    PubMed Central

    Royle, Pamela

    2015-01-01

    Objectives A bibliometric analysis of the UK National Institute for Health Research (NIHR) Health Technology Assessment (HTA) monographs and their related journal articles by: (1) exploring the differences in citations to the HTA monographs in Google Scholar (GS), Scopus and Web of Science (WoS), and (2) comparing Scopus citations to the monographs with their related journal articles. Setting A study of 111 HTA monographs published in 2010 and 2011, and their external journal articles. Main outcome measures Citations to the monographs in GS, Scopus and WoS, and to their external journal articles in Scopus. Results The number of citations varied among the three databases, with GS having the highest and WoS the lowest; however, the citation-based rankings among the databases were highly correlated. Overall, 56% of monographs had a related publication, with the highest proportion for primary research (76%) and lowest for evidence syntheses (43%). There was a large variation in how the monographs were cited, compared to journal articles, resulting in more frequent problems, with unlinked citations in Scopus and WoS. When comparing differences in the number of citations between monograph publications with their related journal articles from the same project, we found that monographs received more citations than their journal articles for evidence syntheses and methodology projects; by contrast, journal articles related to primary research monographs were more highly cited than their monograph. Conclusions The numbers of citations to the HTA monographs differed considerably between the databases, but were highly correlated. When a HTA monograph had a journal article from the same study, there were more citations to the journal article for primary research, but more to the monographs for evidence syntheses. Citations to the related journal articles were more reliably recorded than citations to the HTA monographs. PMID:25694457

  10. Bibliometrics of NIHR HTA monographs and their related journal articles.

    PubMed

    Royle, Pamela; Waugh, Norman

    2015-02-18

    A bibliometric analysis of the UK National Institute for Health Research (NIHR) Health Technology Assessment (HTA) monographs and their related journal articles by: (1) exploring the differences in citations to the HTA monographs in Google Scholar (GS), Scopus and Web of Science (WoS), and (2) comparing Scopus citations to the monographs with their related journal articles. A study of 111 HTA monographs published in 2010 and 2011, and their external journal articles. Citations to the monographs in GS, Scopus and WoS, and to their external journal articles in Scopus. The number of citations varied among the three databases, with GS having the highest and WoS the lowest; however, the citation-based rankings among the databases were highly correlated. Overall, 56% of monographs had a related publication, with the highest proportion for primary research (76%) and lowest for evidence syntheses (43%). There was a large variation in how the monographs were cited, compared to journal articles, resulting in more frequent problems, with unlinked citations in Scopus and WoS. When comparing differences in the number of citations between monograph publications with their related journal articles from the same project, we found that monographs received more citations than their journal articles for evidence syntheses and methodology projects; by contrast, journal articles related to primary research monographs were more highly cited than their monograph. The numbers of citations to the HTA monographs differed considerably between the databases, but were highly correlated. When a HTA monograph had a journal article from the same study, there were more citations to the journal article for primary research, but more to the monographs for evidence syntheses. Citations to the related journal articles were more reliably recorded than citations to the HTA monographs. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please

  11. [Google Scholar and the h-index in biomedicine: the popularization of bibliometric assessment].

    PubMed

    Cabezas-Clavijo, A; Delgado-López-Cózar, E

    2013-01-01

    The aim of this study is to review the features, benefits and limitations of the new scientific evaluation products derived from Google Scholar, such as Google Scholar Metrics and Google Scholar Citations, as well as the h-index, which is the standard bibliometric indicator adopted by these services. The study also outlines the potential of this new database as a source for studies in Biomedicine, and compares the h-index obtained by the most relevant journals and researchers in the field of intensive care medicine, based on data extracted from the Web of Science, Scopus and Google Scholar. Results show that although the average h-index values in Google Scholar are almost 30% higher than those obtained in Web of Science, and about 15% higher than those collected by Scopus, there are no substantial changes in the rankings generated from one data source or the other. Despite some technical problems, it is concluded that Google Scholar is a valid tool for researchers in Health Sciences, both for purposes of information retrieval and for the computation of bibliometric indicators.

  12. A critical review of the development, current hotspots, and future directions of Lake Taihu research from the bibliometrics perspective.

    PubMed

    Zhang, Yunlin; Yao, Xiaolong; Qin, Boqiang

    2016-07-01

    Lake Taihu, as the important drinking water source of the Yangtze River Delta urban agglomeration and the third largest freshwater lake in China, has experienced serious lake eutrophication and water quality deterioration in the past three decades. Growing scientific, political, and public attention has been given to the water quality of Lake Taihu. This study aimed to conduct a comparative quantitative and qualitative analysis of the development, current hotspots, and future directions of Lake Taihu research using a bibliometric analysis of eight well-studied lakes (Lake Taihu, Lake Baikal, Lake Biwa, Lake Erie, Lake Michigan, Lake Ontario, Lake Superior and Lake Victoria) around the world based on the Science Citation Index (SCI) database. A total of 1582 papers discussing Lake Taihu research were published in 322 journals in the past three decades. However, the first paper about Lake Taihu research was not found in the SCI database until 1989, and there were only zero, one, or two papers each year from 1989 to 1995. There had been rapid development in Lake Taihu research since 1996 and a sharp increase in papers since 2005. A keyword analysis showed that "sediment," "eutrophication", "Microcystis aeruginosa", "cyanobacterial blooms", and "remote sensing" were the most frequently used keywords of the study subject. Owing to its significant impact on aquatic ecosystems, a crucial emphasis has been placed on climate change recently. In addition, the future focuses of research directions, including (1) environmental effects of physical processes; (2) nutrient cycles and control and ecosystem responses; (3) cyanobacteria bloom monitoring, causes, forecast and management; (4) eutrophication and climate change interactions; and (5) ecosystem degradation mechanism and ecological practice of lake restoration, are presented based on the keyword analysis. Through multidisciplinary fields (physics, chemistry, and biology) cross and synthesis study of Lake Taihu, the

  13. [New bibliometric indicators. Is this the end of the impact factor era?].

    PubMed

    Berhidi, Anna; Szluka, Péter; Vasas, Lívia

    2009-06-01

    More and more bibliometric indicators emerge beside the impact factor, and a few of them are promising performance indicators. The aim of the study is to show briefly, but clearly the newest bibliometric measure numbers - like the recent enhancements of Journal Citation Report Web, Hirsch-index, Eigenfactor and SCImago Journal & Country Rank algorithms - focusing on the ranking of oncological journals, and to demonstrate the similarities and differences of the results with some examples. There are unified and well-structured web pages behind the newly appeared indicators, and some of the new numbers are presented in the well-known databases (Web of Science, Scopus) as scientific measures. The ranking of the compared oncological journals based on the different indicators show more similarities than differences, but more in-depth studies are required to find out how the results converge on any scientific area. There are some other methods, such as usage factor of the journals, beyond the indicators based on the citations. But the main point is that any ranking system should be a valid and correct representation of the scientific quality.

  14. The Malaria in Pregnancy Library: a bibliometric review

    PubMed Central

    2012-01-01

    Background The Malaria in Pregnancy (MiP) Library is a bibliographic database that was created by the MiP Consortium in 2005 and is updated every four months using a standardized search protocol. A bibliometric review was conducted of the contents of the Library to determine dynamics in the type, content and volume of literature on malaria in pregnancy over time. Methods Data on year of publication, type, language, country of first-author affiliation and content (topic) were extracted from entries in the MiP Library and plotted over time. Results By January 2012, the MiP Library contained 5,346 entries, consisting of 3,721 journal articles (69.6%), 697 reports (13.0%), 219 academic theses (4.1%), 92 books or book chapters (1.7%), 487 conference proceedings (9.1%), 68 registered studies (1.3%) and 62 ‘other’ (1.2%). Most of the sources were in English language (87.3%), followed by French (7.5%) and Spanish (1.5%). Over 40% of source material was publicly available online (42.4%) and the remaining with restricted access (35.0%) or otherwise unavailable (22.7%). The number of journal articles related to malaria in pregnancy increased from 41 in the 1960s, to 708 in the 1990s, and 1,895 between 2000 and 2009, and the variety of themes has increased over time. English-language articles were sourced from 737 different journals. The top three journals were the American Journal of Tropical Medicine and Hygiene (184), Malaria Journal (158) and the Transactions of the Royal Society of Tropical Medicine and Hygiene (131). Conclusion The last decade has seen a dramatic increase in publications related to malaria in pregnancy, and an increasing proportion of these are publically available online. The MiP Library is a useful, scholarly source for literature and systematic reviews related to malaria in pregnancy. PMID:23110589

  15. Bibliometric analysis of the top 100 cited cardiovascular articles.

    PubMed

    Shuaib, Waqas; Khan, Muhammad S; Shahid, Hassan; Valdes, Emilio A; Alweis, Richard

    2015-04-01

    The number of citations an article receives is an important indication of its impact and contribution to the clinical world. There is a paucity of literature concerning top article citations in cardiology. The main objective of this investigation was to bridge this gap and to provide readers a practical guide in evaluating the cardiovascular literature. Scopus Library database was searched to determine the citations of all published cardiovascular articles. One hundred two journals were included in our investigation under the Institute of Science Information Web of Science subject category "cardiology, cardiovascular, and heart." We did not apply any time or study-type restriction in our search. The top 100 cited articles were selected and analyzed by 2 independent investigators. The journal with the highest number of top 100 cited articles was Circulation with 36, followed by 28 in the European Heart Journal. A statistically significant association was found between the journal impact factor and the number of top 100 cited articles (p <0.005). United States had the highest number of articles (49). Contrary to bibliometric analyses published in other medical fields, the largest subset of the cardiology articles (n = 42) was published in the 5-year period from 2006 to 2010. General medical journals such as The Lancet (n = 4) and The New England Journal of Medicine (n = 1) contributed only 5 articles to the list despite their extremely high impact factors. In conclusion, our analysis provides an insight on the citation frequency of top cited articles published in cardiovascular medicine to help recognize the quality of the works, discoveries, and the trends steering cardiology. Copyright © 2015 Elsevier Inc. All rights reserved.

  16. Vulnerabilities—bibliometric analysis and literature review of evolving concepts

    NASA Astrophysics Data System (ADS)

    Giupponi, Carlo; Biscaro, Claudio

    2015-12-01

    In this work we analyse the evolution of the vulnerability concept in the research streams of climate change adaptation (CCA) and disaster risk reduction (DRR). We combine a traditional literature review with data mining procedures applied to bibliographic databases to reconstruct the history of the concept within various research topics, showing its evolution and convergences over time. To do that, we integrate different methods combining machine learning algorithms with network and cluster analyses to examine a set of 3757 articles, analysing their distinctive features and similarities on the basis of their contents as well as co-authorships. Bibliometric analyses enable the identification of different communities of articles, pinpointing key papers and authors, while literature review makes it possible to assess the concept of vulnerability evolved within and beyond research communities and scientific networks. Moreover, this work examines the role played by documents published by UN institutions (UNDRO, UNISDR, IPCC) in contributing to the evolution of vulnerability and related concepts. Results show that signs of convergence are evident between the two research streams, and that the IPCC reports have played a major role in proposing solutions for unifying definitions of vulnerability. We observe that the phases of preparation of the IPCC reports are very rich in methodological and terminological developments, while after publication, the literature shows evident signs of propagation of the proposed concepts. The DRR research stream developed before the research stream on CCA, but the latter flourished rapidly and became much larger in terms of number of publications. Nevertheless, in terms of contents, adaptation studies and the IPCC have shown increasing adoption of the concepts developed within the disaster research stream, in particular with regard to the interpretation of vulnerability as one of the dimensions of risk.

  17. The Malaria in Pregnancy Library: a bibliometric review.

    PubMed

    van Eijk, Anna M; Hill, Jenny; Povall, Sue; Reynolds, Alison; Wong, Helen; Ter Kuile, Feiko O

    2012-10-30

    The Malaria in Pregnancy (MiP) Library is a bibliographic database that was created by the MiP Consortium in 2005 and is updated every four months using a standardized search protocol. A bibliometric review was conducted of the contents of the Library to determine dynamics in the type, content and volume of literature on malaria in pregnancy over time. Data on year of publication, type, language, country of first-author affiliation and content (topic) were extracted from entries in the MiP Library and plotted over time. By January 2012, the MiP Library contained 5,346 entries, consisting of 3,721 journal articles (69.6%), 697 reports (13.0%), 219 academic theses (4.1%), 92 books or book chapters (1.7%), 487 conference proceedings (9.1%), 68 registered studies (1.3%) and 62 'other' (1.2%). Most of the sources were in English language (87.3%), followed by French (7.5%) and Spanish (1.5%). Over 40% of source material was publicly available online (42.4%) and the remaining with restricted access (35.0%) or otherwise unavailable (22.7%). The number of journal articles related to malaria in pregnancy increased from 41 in the 1960s, to 708 in the 1990s, and 1,895 between 2000 and 2009, and the variety of themes has increased over time. English-language articles were sourced from 737 different journals. The top three journals were the American Journal of Tropical Medicine and Hygiene (184), Malaria Journal (158) and the Transactions of the Royal Society of Tropical Medicine and Hygiene (131). The last decade has seen a dramatic increase in publications related to malaria in pregnancy, and an increasing proportion of these are publically available online. The MiP Library is a useful, scholarly source for literature and systematic reviews related to malaria in pregnancy.

  18. Reading factor: a bibliometric tool to manage a virtual library.

    PubMed

    Thirion, B; Darmoni, S J; Benichou, J

    2001-01-01

    Among the many bibliometric criteria used to evaluate biomedical journals, the impact factor is the most commonly used. Despite its limitations, it quantifies the influence of a journal on secondary publications. It does not however evaluate the practical usefulness of primary documents. Usefulness is field-related and varies greatly among specialities. We introduce a new bibliographic criterion, the "reading factor", and define it as the ratio between the number of electronic consultations of a particular journal (i.e., number of clicks on a hyper-link) and the mean number of electronic consultations of all the journals studied (itself calculated by dividing the total number of electronic accesses by the number of journals in the database). We describe its observed distribution, relative to that of the impact factor, based on electronic consultation records from our University Hospital medical digital library, where full-text electronic versions of 45 major biomedical journals have been available since December 1997. From this analysis we found no correlation between the 1999 reading factor and the 1998 impact factor of these 45 journals, and we observed a dramatic change in the hierarchy of journals upon using the reading factor as the yardstick rather than the impact factor. Moreover, we describe how using the reading factor has helped in managing the collection of our University Hospital's virtual library. The selection of journals to be discarded from the virtual library for the year 2001 was based on journals' RF values and this process will repeated over the coming years. The reading factor also permits a cost-analysis of a virtual library. The measurement of the reading factor is highly automated, practical and efficient. It appears as a new tool for electronic collection management by librarians, well fitting with economical data.

  19. A bibliometric overview of public health research in Europe.

    PubMed

    Clarke, Aileen; Gatineau, Mary; Grimaud, Olivier; Royer-Devaux, Sandrine; Wyn-Roberts, Nia; Le Bis, Isabelle; Lewison, Grant

    2007-01-01

    Our aim, within the collaborative study SPHERE (Strengthening Public Health Research in Europe), was to produce a bibliometric overview of public health research literature for Europe. A search strategy ('filter') was designed to interrogate the Science Citation Index (SCI) and the Social Science Citation Index (SSCI) databases for research articles published between 01/01/1995 and 31/12/2004 in any language. We analysed output for country by population, Gross Domestic Product (GDP), burden of disease using DALYs, and language. Overlap between the two databases SCI and SSCI was 35%. 210,433 publications were identified after duplicates were removed, a world total of about 20,000 per year. Approximately 7,000 papers per year were produced in Europe and 9,400 by the USA. Thirteen of 28 individual European countries produced more than 100 public health papers per year. Publications per capita were highest in northern European countries. In multiple regression analyses, GDP was a modest predictor (r(2) = 0.53, P < 0.02) of publications for European countries, while population size and disability adjusted life years were not significantly related. Smaller countries and lower producers of public health research were more likely to collaborate with other countries. Of the publications, 3.5% were published in a non-English language, with German the most common. There is marked variation in public health publication by country in Europe. Eastern and southern European countries appear to under-invest in public health research compared with northern European countries and compared to relative health need.

  20. Bibliometric analysis of health services research in otolaryngology journals.

    PubMed

    Sun, Gordon H

    2012-11-01

    Determine current health services research (HSR) publication trends in major general otolaryngology journals. Bibliometric analysis. All main issues of 8 high-impact general-interest otolaryngology journals published worldwide in 2002, 2005, 2008, and 2011 were searched for HSR-related publications. To qualify as HSR, the abstract of the article must discuss access to care, cost, delivery of care, financing, health organizational or system issues, quality of care, resource utilization, and/or health outcomes. Otolaryngology topics were classified as general, pediatrics, oncology, otology and neurotology, sleep disorders, sinonasal disease, facial plastics, and/or laryngology. Other key measures included study authorship and external sponsorship or mechanism of support. Of 5958 total articles, 449 (7.5%) qualified as HSR. There was a statistically significant increase in the number of HSR publications across all journals from 2002 to 2011 (P < .001). Outcomes research (337, 75.1%) was the most common type of HSR being published. The most common subject was oncology (112, 24.9%), whereas the least represented was trauma and facial plastics (4, 0.9%). First and corresponding authors were based in 31 countries, although the United States was the predominant country of origin. Nearly 95% of HSR articles in the current sample demonstrated multidisciplinary authorship. An estimated 22.9% of first authors and 17.8% of corresponding authors were female. Two-thirds of HSR publications reported no external sponsor, whereas the remainder was supported most commonly by philanthropy and hospital-based sources. Health services research is an international, multidisciplinary field of inquiry with an increasing presence in major otolaryngology journals.

  1. [Bibliometric analysis of current glaucoma research based on Pubmed database].

    PubMed

    Huang, Wen-bin; Wang, Wei; Zhou, Min-wen; Chen, Shi-da; Zhang, Xiu-lan

    2013-11-01

    To survey the distribution pattern and subject domain knowledge of worldwide glaucoma research based on literatures in Pubmed database. Literatures on glaucoma published in 2007 to 2011 were identified in Pubmed database. The analytic items of an article include published year, country, language author, and journal. After core mesh terms had been characterized by BICOMS, the co-occurrence matrix was built. Cluster analysis was finished by SPSS 20.0. Then visualized network was drawn using ucinet 6.0. Totally 6427 literatures were included, the number of annual articles changed slightly between 2007 and 2011. The United States, England, Germany, Australia, and France together accounted for 77.63% of articles. There were 52 high-frequency subjects and hot topics were clustered into the following 10 categories: (1) Pathology of optic disc and nerve fibers and OCT application, (2) METHODS: of visual field (VF) and visual function examination, (3) Glaucoma drug medications, (4) Pathology and physiology of primary open angle glaucoma (POAG) including VF and intraocular pressure (IOP), (5) Glaucoma surgery, (6) Gene research related to POAG, (7) Glaucoma disease pathology and animal models, (8) Ocular hypertension (OHT) induced complications and corneal changes, (9) Etiology of congenital glaucoma and complications, (10) Etiology and epidemiology of glaucoma. The visualized domain knowledge mapping was successfully built. The pathology of optic disc and nerve fibers, medications, and surgery were well developed. Study on IOP and visual field was in the core domain, which have an important link to etiology, diagnosis, and therapy. The researches on glaucomatous gene, disease pathology model, congenital glaucoma, etiology and epidemiology were not developed well, which are of great promotion space. The distribution pattern and subject domain knowledge of worldwide glaucoma research in the recent five years were shown by using bibliometric analysis.Western developed

  2. Accrual Patterns for Clinical Studies Involving Quantitative Imaging: Results of an NCI Quantitative Imaging Network (QIN) Survey

    PubMed Central

    Kurland, Brenda F.; Aggarwal, Sameer; Yankeelov, Thomas E.; Gerstner, Elizabeth R.; Mountz, James M.; Linden, Hannah M.; Jones, Ella F.; Bodeker, Kellie L.; Buatti, John M.

    2017-01-01

    Patient accrual is essential for the success of oncology clinical trials. Recruitment for trials involving the development of quantitative imaging biomarkers may face different challenges than treatment trials. This study surveyed investigators and study personnel for evaluating accrual performance and perceived barriers to accrual and for soliciting solutions to these accrual challenges that are specific to quantitative imaging-based trials. Responses for 25 prospective studies were received from 12 sites. The median percent annual accrual attained was 94.5% (range, 3%–350%). The most commonly selected barrier to recruitment (n = 11/25, 44%) was that “patients decline participation,” followed by “too few eligible patients” (n = 10/25, 40%). In a forced choice for the single greatest recruitment challenge, “too few eligible patients” was the most common response (n = 8/25, 32%). Quantitative analysis and qualitative responses suggested that interactions among institutional, physician, and patient factors contributed to accrual success and challenges. Multidisciplinary collaboration in trial design and execution is essential to accrual success, with attention paid to ensuring and communicating potential trial benefits to enrolled and future patients. PMID:28127586

  3. [Scientific output on transsexuality in the Spanish biomedical literature: bibliometric and content analyses (1973-2011)].

    PubMed

    Navarro-Pérez, Patricia; Ortiz-Gómez, Teresa; Gil-García, Eugenia

    2015-01-01

    To explore the scientific output on transsexuality in the Spanish biomedical literature between 1973 and 2011, through bibliometric and content analyses. We carried out a descriptive, cross-sectional study of Spanish biomedical articles on transsexuality published between 1973 and 2011. The data sources consisted of Índice Médico Español and ISOC-Ciencias Sociales y Humanidades. Bibliometric and content analyses were performed. A total of 65 papers were analyzed. Knowledge on transsexuality in Spain began to appear in medical journals between 1973 and 1984. A decade of intense productivity began in 1996 and the number of journals publishing articles on transsexuality multiplied in the following years. Until 2006, the year with the most biomedical productivity, biomedical discourses reproduced representations of transsexuality anchored in biological determinism. From 2008-2011, professionals writing on the topic incorporated feminist theories and social perspectives in their discourses. In the last quarter of the twentieth century, the dominant medical discourse considered manifestations of transsexual people from a biologist perspective that conceives transsexuality as a configuration mismatch between sex and gender. The emergence of new identity categories and medical reflection from non-essentialist and non-normative gender perspectives has improved the clinical management of transsexuality. Copyright © 2014 SESPAS. Published by Elsevier Espana. All rights reserved.

  4. Quantitative genetic bases of anthocyanin variation in grape (Vitis vinifera L. ssp. sativa) berry: a quantitative trait locus to quantitative trait nucleotide integrated study.

    PubMed

    Fournier-Level, Alexandre; Le Cunff, Loïc; Gomez, Camila; Doligez, Agnès; Ageorges, Agnès; Roux, Catherine; Bertrand, Yves; Souquet, Jean-Marc; Cheynier, Véronique; This, Patrice

    2009-11-01

    The combination of QTL mapping studies of synthetic lines and association mapping studies of natural diversity represents an opportunity to throw light on the genetically based variation of quantitative traits. With the positional information provided through quantitative trait locus (QTL) mapping, which often leads to wide intervals encompassing numerous genes, it is now feasible to directly target candidate genes that are likely to be responsible for the observed variation in completely sequenced genomes and to test their effects through association genetics. This approach was performed in grape, a newly sequenced genome, to decipher the genetic architecture of anthocyanin content. Grapes may be either white or colored, ranging from the lightest pink to the darkest purple tones according to the amount of anthocyanin accumulated in the berry skin, which is a crucial trait for both wine quality and human nutrition. Although the determinism of the white phenotype has been fully identified, the genetic bases of the quantitative variation of anthocyanin content in berry skin remain unclear. A single QTL responsible for up to 62% of the variation in the anthocyanin content was mapped on a Syrah x Grenache F(1) pseudo-testcross. Among the 68 unigenes identified in the grape genome within the QTL interval, a cluster of four Myb-type genes was selected on the basis of physiological evidence (VvMybA1, VvMybA2, VvMybA3, and VvMybA4). From a core collection of natural resources (141 individuals), 32 polymorphisms revealed significant association, and extended linkage disequilibrium was observed. Using a multivariate regression method, we demonstrated that five polymorphisms in VvMybA genes except VvMybA4 (one retrotransposon, three single nucleotide polymorphisms and one 2-bp insertion/deletion) accounted for 84% of the observed variation. All these polymorphisms led to either structural changes in the MYB proteins or differences in the VvMybAs promoters. We concluded that

  5. Quantitative studies on roast kinetics for bioactives in coffee.

    PubMed

    Lang, Roman; Yagar, Erkan Firat; Wahl, Anika; Beusch, Anja; Dunkel, Andreas; Dieminger, Natalie; Eggers, Rudolf; Bytof, Gerhard; Stiebitz, Herbert; Lantz, Ingo; Hofmann, Thomas

    2013-12-11

    Quantitative analysis of the bioactives trigonelline (1), N-methylpyridinium (2), caffeine (3), and caffeoylquinic acids (4) in a large set of roasted Arabica (total sample size n = 113) and Robusta coffees (total sample size n = 38) revealed that the concentrations of 1 and 4 significantly correlated with the roasting color (P < 0.001, two tailed), whereas that of 2 significantly correlated inversely with the color (P < 0.001, two tailed). As dark-roasted coffees were rich in N-methylpyridinium whereas light-roasted coffees were rich in trigonelline and caffeoylquinic acids, manufacturing of roast coffees rich in all four bioactives would therefore necessitate blending of two or even more coffees of different roasting colors. Additional experiments on the migration rates during coffee brewing showed that all four bioactives were nearly quantitatively extracted in the brew (>90%) when a water volume/coffee powder ratio of >16 was used.

  6. [Bibliometrics and web use: the birth of altmetrics].

    PubMed

    Scotti, Valeria

    2015-04-01

    Counting citations that a research article received by other articles was the traditional bibliometric method for the evaluation of a scientific research. Citations have been used both to evaluate a scientific paper - usually in conjunction with the peer review methods - and to determine the quality of a scientific research output. The development of tools even more Web 2.0 oriented has profoundly changed the scientific communication process. In this context, many web tools have emerged including the so-called "social media" (e-i., Facebook, Twitter). Hence the need for new indicators to measure the influence of these tools on the scientific community and the emergence of alternative metrics. Altmetrics combines the traditional bibliometrics tool with the use of the web. Formulated with the purpose to measure new aspects of scientific production, these new metrics are placed in order to complement and supplement the existing indicators rather than act as their replacements.

  7. Bibliometrics, citation indexing, and the journals of nursing.

    PubMed

    Smith, Derek R; Hazelton, Michael

    2008-12-01

    Bibliometric research has risen in popularity during recent years and an increasing number of investigations now have examined the nursing literature. Our article provides a comprehensive overview of citation-based research in the nursing profession, as well as a discussion of bibliometrics, journal impact factors, and international publishing trends. The debate on evidence-based practice and its potential influence and relevance for nursing scholars is also covered. Although journal performance indicators are, no doubt, important for the contemporary nursing academic, it is the core research skills and attributes that nursing scholars, academics, and educators will need to consider more carefully in future if the next generation of professional nurse researchers is to truly flourish.

  8. Exploring the Relationship between the Engineering and Physical Sciences and the Health and Life Sciences by Advanced Bibliometric Methods

    PubMed Central

    Waltman, Ludo; van Raan, Anthony F. J.; Smart, Sue

    2014-01-01

    We investigate the extent to which advances in the health and life sciences (HLS) are dependent on research in the engineering and physical sciences (EPS), particularly physics, chemistry, mathematics, and engineering. The analysis combines two different bibliometric approaches. The first approach to analyze the ‘EPS-HLS interface’ is based on term map visualizations of HLS research fields. We consider 16 clinical fields and five life science fields. On the basis of expert judgment, EPS research in these fields is studied by identifying EPS-related terms in the term maps. In the second approach, a large-scale citation-based network analysis is applied to publications from all fields of science. We work with about 22,000 clusters of publications, each representing a topic in the scientific literature. Citation relations are used to identify topics at the EPS-HLS interface. The two approaches complement each other. The advantages of working with textual data compensate for the limitations of working with citation relations and the other way around. An important advantage of working with textual data is in the in-depth qualitative insights it provides. Working with citation relations, on the other hand, yields many relevant quantitative statistics. We find that EPS research contributes to HLS developments mainly in the following five ways: new materials and their properties; chemical methods for analysis and molecular synthesis; imaging of parts of the body as well as of biomaterial surfaces; medical engineering mainly related to imaging, radiation therapy, signal processing technology, and other medical instrumentation; mathematical and statistical methods for data analysis. In our analysis, about 10% of all EPS and HLS publications are classified as being at the EPS-HLS interface. This percentage has remained more or less constant during the past decade. PMID:25360616

  9. Exploring the relationship between the engineering and physical sciences and the health and life sciences by advanced bibliometric methods.

    PubMed

    Waltman, Ludo; van Raan, Anthony F J; Smart, Sue

    2014-01-01

    We investigate the extent to which advances in the health and life sciences (HLS) are dependent on research in the engineering and physical sciences (EPS), particularly physics, chemistry, mathematics, and engineering. The analysis combines two different bibliometric approaches. The first approach to analyze the 'EPS-HLS interface' is based on term map visualizations of HLS research fields. We consider 16 clinical fields and five life science fields. On the basis of expert judgment, EPS research in these fields is studied by identifying EPS-related terms in the term maps. In the second approach, a large-scale citation-based network analysis is applied to publications from all fields of science. We work with about 22,000 clusters of publications, each representing a topic in the scientific literature. Citation relations are used to identify topics at the EPS-HLS interface. The two approaches complement each other. The advantages of working with textual data compensate for the limitations of working with citation relations and the other way around. An important advantage of working with textual data is in the in-depth qualitative insights it provides. Working with citation relations, on the other hand, yields many relevant quantitative statistics. We find that EPS research contributes to HLS developments mainly in the following five ways: new materials and their properties; chemical methods for analysis and molecular synthesis; imaging of parts of the body as well as of biomaterial surfaces; medical engineering mainly related to imaging, radiation therapy, signal processing technology, and other medical instrumentation; mathematical and statistical methods for data analysis. In our analysis, about 10% of all EPS and HLS publications are classified as being at the EPS-HLS interface. This percentage has remained more or less constant during the past decade.

  10. The information value of early career productivity in mathematics: a ROC analysis of prediction errors in bibliometricly informed decision making.

    PubMed

    Lindahl, Jonas; Danell, Rickard

    2016-01-01

    The aim of this study was to provide a framework to evaluate bibliometric indicators as decision support tools from a decision making perspective and to examine the information value of early career publication rate as a predictor of future productivity. We used ROC analysis to evaluate a bibliometric indicator as a tool for binary decision making. The dataset consisted of 451 early career researchers in the mathematical sub-field of number theory. We investigated the effect of three different definitions of top performance groups-top 10, top 25, and top 50 %; the consequences of using different thresholds in the prediction models; and the added prediction value of information on early career research collaboration and publications in prestige journals. We conclude that early career performance productivity has an information value in all tested decision scenarios, but future performance is more predictable if the definition of a high performance group is more exclusive. Estimated optimal decision thresholds using the Youden index indicated that the top 10 % decision scenario should use 7 articles, the top 25 % scenario should use 7 articles, and the top 50 % should use 5 articles to minimize prediction errors. A comparative analysis between the decision thresholds provided by the Youden index which take consequences into consideration and a method commonly used in evaluative bibliometrics which do not take consequences into consideration when determining decision thresholds, indicated that differences are trivial for the top 25 and the 50 % groups. However, a statistically significant difference between the methods was found for the top 10 % group. Information on early career collaboration and publication strategies did not add any prediction value to the bibliometric indicator publication rate in any of the models. The key contributions of this research is the focus on consequences in terms of prediction errors and the notion of transforming uncertainty

  11. Significant pathways detection in osteoporosis based on the bibliometric network.

    PubMed

    Sun, G J; Guo, T; Chen, Y; Xu, B; Guo, J H; Zhao, J N

    2013-01-01

    Osteoporosis is a significant public health issue worldwide. The underlying mechanism of osteoporosis is an imbalance between bone resorption and bone formation. However, the exact pathology is still unclear, and more related genes are on demand. Here, we aim to identify the differentially expressed genes in osteoporosis patients and control. Biblio-MetReS, a tool to reconstruct gene and protein networks from automated literature analysis, was used for identifying potential interactions among target genes. Relevant signaling pathways were also identified through pathway enrichment analysis. Our results showed that 56 differentially expressed genes were identified. Of them, STAT1, CXCL10, SOCS3, ADM, THBS1, SOD2, and ERG2 have been demonstrated involving in osteoporosis. Further, a bibliometric network was constructed between DEGs and other genes through the Biblio-MetReS. The results showed that STAT1 could interact with CXCL10 through Toll-like receptor signaling pathway and Chemokine signaling pathway. STAT1 interacted with SOCS3 through JAK/STAT pathway.

  12. Study of proper conditions for quantitative atom-probe analysis

    NASA Astrophysics Data System (ADS)

    Rolander, Ulf; Andrén, Hans-Olof

    1994-03-01

    Atom-probe microanalysis is a truly quantitative method only if certain requirements are fulfilled. Field evaporation must only happen when the detector system is active; ions must travel from specimen to detector without being obstructed; and ions must be detected with the same probability regardless of mass and energy. Designs and methods to achieve these requirements are presented in the paper, such as a controlled high-voltage pulser, a detector with good and variable multi-hit resolution, ion optical alignment procedures, and a method to statistically correct for pile-up in the detector.

  13. Mantle dentine in man--a quantitative microradiographic study.

    PubMed

    Herr, P; Holz, J; Baume, L J

    1986-06-01

    50 microradiographs taken in a standardized manner of midsagittal ground sections of teeth of individuals aged 18 to 56 years were densitometrically evaluated along a track passing through enamel, dentine and an aluminium stepwedge. Semi-quantitative analysis of mineral density uniformly showed an irregular platform representing circumpulpal dentine and a peripheral down slope in the region of the amelodentinal junction, representing mantle dentine. The width of this less mineralized peripheral zone measured on densitometric recordings averaged 150 microns (+/- 50). Quantitative analysis of the two dentinal regions permitted the calculation of the mineral content in terms of volume percentage using both a graphic method and an electronic computer method. The sections were also examined by polarized light microscopy which clearly visualized the presence of peripheral mantle dentine. The mean mineral density of circumpulpal dentine was 46% according to both the graphic and the computer methods; mantle dentine yielded means close to 42% according by both methods. The 4% difference in density between circumpulpal dentine and mantle dentine proved to be statistically significant; there was no significant difference between the means obtained graphically and those obtained electronically. The need for further investigation of this region of the amelodentinal junction was stressed.

  14. [Bibliometric analysis of Revista Médica del IMSS in the Scopus database for the period between 2005-2013].

    PubMed

    García-Gómez, Francisco; Ramírez-Méndez, Fernando

    2015-01-01

    To analyze the number of articles of Revista Médica del Instituto Mexicano del Seguro Social (Rev Med Inst Mex Seguro Soc) in the Scopus database and describe principal quantitative bibliometric indicators of scientific publications during the period between 2005 to 2013. Scopus database was used limited to the period between 2005 to 2013. The analysis cover mainly title of articles with the title of Revista Médica del Instituto Mexicano del Seguro Social and its possible modifications. For the analysis, Scopus, Excel and Access were used. 864 articles were published during the period between 2005 to 2013 in the Scopus database. We identified authors with the highest number of contributions including articles with the highest citation rate and forms of documents cited. We also divided articles by subjects, types of documents and other bibliometric indicators which characterize the publications. The use of Scopus brings the possibility of analyze with an external tool the visibility of the scientific production published in the Revista Médica del IMSS. The use of this database also contributes to identify the state of science in México, as well as in the developing countries.

  15. A quantitative study of enterotoxin production by sheep milk staphylococci.

    PubMed Central

    Bautista, L; Gaya, P; Medina, M; Nuñez, M

    1988-01-01

    Of 124 staphylococcal strains isolated from sheep milk, 78 produced enterotoxin A, B, C, or D when evaluated by an enzyme-linked immunosorbent assay. Enterotoxins A and D, elaborated by 44 and 43 strains, respectively, showed the highest incidence. Enterotoxin production by coagulase-negative strains (one Staphylococcus cohnii, three S. epidermidis, five S. haemolyticus, and four S. xylosus) was detected. Linear and logarithmic-logarithmic regressions of optical density on enterotoxin concentration yielded the best-fitting equations for enterotoxin quantitation. A significantly higher incidence of enterotoxin producers and significantly higher levels of enterotoxins produced were recorded for coagulase-positive, thermostable nuclease-positive, hemolysis-positive, or mannitol-positive strains. Mannitol utilization was the best test for discriminating between enterotoxigenic and nonenterotoxigenic staphylococci. PMID:3355142

  16. Studying learning in the healthcare setting: the potential of quantitative diary methods.

    PubMed

    Ciere, Yvette; Jaarsma, Debbie; Visser, Annemieke; Sanderman, Robbert; Snippe, Evelien; Fleer, Joke

    2015-08-01

    Quantitative diary methods are longitudinal approaches that involve the repeated measurement of aspects of peoples' experience of daily life. In this article, we outline the main characteristics and applications of quantitative diary methods and discuss how their use may further research in the field of medical education. Quantitative diary methods offer several methodological advantages, such as measuring aspects of learning with great detail, accuracy and authenticity. Moreover, they enable researchers to study how and under which conditions learning in the health care setting occurs and in which way learning can be promoted. Hence, quantitative diary methods may contribute to theory development and the optimization of teaching methods in medical education.

  17. The hundred most-cited publications in microbiota of diabetes research: A bibliometric analysis.

    PubMed

    Tian, Jiaxing; Li, Min; Lian, Fengmei; Tong, Xiaolin

    2017-09-01

    Bibliometric analysis is an approach to evaluate the circumstances and trends in specific research field over time and to provide inspiration in future research and policy. Researches have a tremendous increase focus on the role of the microbiota in the development of diabetes in recent years; however, there is no published literature conducting a bibliometric analysis to explore the tendency. The aim of this study was to provide a detailed evaluation of the hundred most cited articles in microbiota of diabetes research. The database of the Web of Science was utilized for identification of articles. The top 100 were selected for further analysis of authorship, number of citations, article type, source journal, geographic origin, and interactions. The articles selected were published from 2007 to 2015. The total citations ranged from 1289 to 35, citation density ranged from 163.75 to 6.5. The article type included basic science (n = 32), review (n = 29), expert opinion (n = 19), cross-sectional study (n = 12), RCT (n = 3), and others (n = 5). The study content included pathogenesis (n = 58), risk factor (n = 11), modifying of intestinal microbiota (n = 10), prebiotic treatment (n = 8), antibiotic treatment (n = 4), diet control (n = 4), and others (n = 5). The 100 most cited articles were published in 59 journals. Among them, Diabetes (n = 7), Diabetologia (n = 7), and Plos one (n = 7) published the most T100 articles. In total, 24 countries and 174 scientific research institutions participated in those researches. USA (n = 32) and Belgium (n = 22) were the leading countries in this field, followed by France (n = 18) and Finland (n = 16). Patrice D. Cani contributed the most top cited articles (n = 15). This bibliometric study is likely to include a list of intellectual milestones focused on microbiota of diabetes research in the past decade, which provides insights into the

  18. Nursing research in Spain: bibliometrics of references of research papers in the decade 1985-1994.

    PubMed

    Pardo, C; Reolid, M; Delicado, M V; Mallebrera, E; García-Meseguer, M J

    2001-09-01

    Spain is one of the few European countries to have recently totally incorporated the study of nursing into the university sector. Bibliometric studies may be of a great help for the consolidation of nursing research. The aim of this paper is to describe bibliographic references in Spanish nursing research papers and their evolution over a decade. The method consists of a retrospective bibliometric study of a sample (cluster sampling) of 622 research papers (original papers and review papers), which were contained in the Spanish nursing journals Enfermería Científica, Revista ROL de Enfermería, Enfermería Clínica and Enfermería Integral, and published from 1985 to 1994. The journal Nursing Research was selected for qualitative comparative purposes. A series of classic bibliometric indexes were used. The mean of references per paper is 10.64 +/- 10.42; this increased over time (P < 0.001). Review papers have more references (P < 0.001). Price index (percentage of references published during the last 5 years) is 44% and the Insularity (percentage of references published in same country as the article) is 55%. References to journals predominate (58.6%), with a growing tendency for references to Spanish nursing journals, although they are still scarce (18.1% of the references to journals). Spanish is the language of most of the references (60.3%), the second language being English (36.1%). Bibliographic references in Spanish nursing research papers are scarce and not very specific: this happens both in regard to Nursing Research and to publications in other national and international science areas. However, there is an increasing tendency of references (including references to nursing journals) in the period analysed. The age of the references places Spanish nursing in an intermediate position between the 'hard' sciences and the humanities; and, according to the type of documentation used, we find it halfway between experimental and natural sciences, and

  19. Critical review of a quantitative study of a specialty in high energy particle physics

    SciTech Connect

    White, D H; Sullivan, D

    1980-01-01

    A review is made of the authors' series of quantitative, historical, and social studies of the weak interactions of elementary particles. A short intellectual history, the quantitative methodology, and a summary of the papers analyzing specific episodes in this field are presented. The social organization of the field is described, and an overall policy for resource management is discussed. 6 figures, 3 tables.

  20. Cardiac trauma from angiographic injections. A quantitative study.

    PubMed

    Abbott, J A; Lipton, M J; Kosek, J; Hayashi, T; Lee, F C

    1978-01-01

    To relate angiographic injections to potential cardiac trauma, we verified a mathematic theory that allows quantitative definition of the kinetic energy content of contrast jets emanating from the exit holes of angiographic catheters. Cineangiographic recordings of a range of jets of known energy content were obtained in 18 cardiac canine experiments and energy content and dissipation were quantified precisely from center line to jet edge. All contrast jets produced in clinical angiographic practice were turbulent, even those from hand injections into the coronary arteries. Energy content was related to an estimated cardiac wall damage threshold. At energy levels and damage thresholds predicted by the theory and computations, a traumatic spectrum was found by cineradiology and microscopic examination. A unique curve independent of jet Reynolds number was discovered relating the penetration of the contrast jet into the intravascular blood to the potential for cardiac trauma. This curve allowed ready calculation of hydraulic energy dissipation for any clinically used angiographic catheter and the definition of safe operational injection flow rates. Thus potential cardiac trauma can be anticipated and prevented.

  1. A quantitative electrophysiological study of motor neurone disease.

    PubMed Central

    Hansen, S; Ballantyne, J P

    1978-01-01

    Thirty-two patients with motor neurone disease were investigated using quantitative electrophysiological techniques. Estimates of the number of surviving motor units in the extensor digitorum brevis muscle and measurements of the electrophysiological parameters of these units are present along with the values for motor nerve conduction velocities. The results indicate that reinnervation in motor neurone disease is sufficient to compensate completely for the loss of up to 50% of the motor neurone pool supplying the muscle. The capacity for reinnervation is greater than we have found in a number of neuropathies but the efficiency of reinnervation decreases as the number of surviving motor units falls. Reinnervation appears to cease when 5% or less of the motor units remain viable. There is no electrophysiological evidence of a preferential loss of fast conducting axons, of pathological slowing of conduction nor of a dying-back process affecting the motor axon. Comparison of the electrophysiological parameters in progressive muscular atrophy and amyotrophic lateral sclerosis shows no significant differences. The underlying pathophysiological mechanisms are discussed in terms of the results. PMID:690647

  2. In situ quantitative study of nanoscale triboelectrification and patterning.

    PubMed

    Zhou, Yu Sheng; Liu, Ying; Zhu, Guang; Lin, Zong-Hong; Pan, Caofeng; Jing, Qingshen; Wang, Zhong Lin

    2013-06-12

    By combining contact-mode atomic force microscopy (AFM) and scanning Kevin probe microscopy (SKPM), we demonstrated an in situ method for quantitative characterization of the triboelectrification process at the nanoscale. We systematically characterized the triboelectric charge distribution, multifriction effect on charge transfer, as well as subsequent charge diffusion on the dielectric surface: (i) the SiO2 surface can be either positively or negatively charged through triboelectric process using Si-based AFM probes with and without Pt coating, respectively; (ii) the triboelectric charges accumulated from multifriction and eventually reached to saturated concentrations of (-150 ± 8) μC/m(2) and (105 ± 6) μC/m(2), respectively; (iii) the charge diffusion coefficients on SiO2 surface were measured to be (1.10 ± 0.03) × 10(-15) m(2)/s for the positive charge and (0.19 ± 0.01) × 10(-15) m(2)/s for the negative charges. These quantifications will facilitate a fundamental understanding about the triboelectric and de-electrification process, which is important for designing high performance triboelectric nanogenerators. In addition, we demonstrated a technique for nanopatterning of surface charges without assistance of external electric field, which has a promising potential application for directed self-assembly of charged nanostructures for nanoelectronic devices.

  3. Quantitative study of single molecule location estimation techniques

    PubMed Central

    Abraham, Anish V.; Ram, Sripad; Chao, Jerry; Ward, E. S.; Ober, Raimund J.

    2010-01-01

    Estimating the location of single molecules from microscopy images is a key step in many quantitative single molecule data analysis techniques. Different algorithms have been advocated for the fitting of single molecule data, particularly the nonlinear least squares and maximum likelihood estimators. Comparisons were carried out to assess the performance of these two algorithms in different scenarios. Our results show that both estimators, on average, are able to recover the true location of the single molecule in all scenarios we examined. However, in the absence of modeling inaccuracies and low noise levels, the maximum likelihood estimator is more accurate than the nonlinear least squares estimator, as measured by the standard deviations of its estimates, and attains the best possible accuracy achievable for the sets of imaging and experimental conditions that were tested. Although neither algorithm is consistently superior to the other in the presence of modeling inaccuracies or misspecifications, the maximum likelihood algorithm emerges as a robust estimator producing results with consistent accuracy across various model mismatches and misspecifications. At high noise levels, relative to the signal from the point source, neither algorithm has a clear accuracy advantage over the other. Comparisons were also carried out for two localization accuracy measures derived previously. Software packages with user-friendly graphical interfaces developed for single molecule location estimation (EstimationTool) and limit of the localization accuracy calculations (FandPLimitTool) are also discussed. PMID:20052043

  4. Quantitative study of single molecule location estimation techniques.

    PubMed

    Abraham, Anish V; Ram, Sripad; Chao, Jerry; Ward, E S; Ober, Raimund J

    2009-12-21

    Estimating the location of single molecules from microscopy images is a key step in many quantitative single molecule data analysis techniques. Different algorithms have been advocated for the fitting of single molecule data, particularly the nonlinear least squares and maximum likelihood estimators. Comparisons were carried out to assess the performance of these two algorithms in different scenarios. Our results show that both estimators, on average, are able to recover the true location of the single molecule in all scenarios we examined. However, in the absence of modeling inaccuracies and low noise levels, the maximum likelihood estimator is more accurate than the nonlinear least squares estimator, as measured by the standard deviations of its estimates, and attains the best possible accuracy achievable for the sets of imaging and experimental conditions that were tested. Although neither algorithm is consistently superior to the other in the presence of modeling inaccuracies or misspecifications, the maximum likelihood algorithm emerges as a robust estimator producing results with consistent accuracy across various model mismatches and misspecifications. At high noise levels, relative to the signal from the point source, neither algorithm has a clear accuracy advantage over the other. Comparisons were also carried out for two localization accuracy measures derived previously. Software packages with user-friendly graphical interfaces developed for single molecule location estimation (EstimationTool) and limit of the localization accuracy calculations (FandPLimitTool) are also discussed.

  5. Quantitative structure-activity relationship studies on nitrofuranyl antitubercular agents

    PubMed Central

    Hevener, Kirk E.; Ball, David M.; Buolamwini, John K.

    2008-01-01

    A series of nitrofuranylamide and related aromatic compounds displaying potent activity against M. tuberculosis has been investigated utilizing 3-Dimensional Quantitative Structure-Activity Relationship (3D-QSAR) techniques. Comparative Molecular Field Analysis (CoMFA) and Comparative Molecular Similarity Indices Analysis (CoMSIA) methods were used to produce 3D-QSAR models that correlated the Minimum Inhibitory Concentration (MIC) values against M. tuberculosis with the molecular structures of the active compounds. A training set of 95 active compounds was used to develop the models, which were then evaluated by a series of internal and external cross-validation techniques. A test set of 15 compounds was used for the external validation. Different alignment and ionization rules were investigated as well as the effect of global molecular descriptors including lipophilicity (cLogP, LogD), Polar Surface Area (PSA), and steric bulk (CMR), on model predictivity. Models with greater than 70% predictive ability, as determined by external validation, and high internal validity (cross validated r2 > .5) have been developed. Incorporation of lipophilicity descriptors into the models had negligible effects on model predictivity. The models developed will be used to predict the activity of proposed new structures and advance the development of next generation nitrofuranyl and related nitroaromatic anti-tuberculosis agents. PMID:18701298

  6. Young people, alcohol, and designer drinks: quantitative and qualitative study.

    PubMed Central

    Hughes, K.; MacKintosh, A. M.; Hastings, G.; Wheeler, C.; Watson, J.; Inglis, J.

    1997-01-01

    OBJECTIVE: To examine the appeal of "designer drinks" to young people. DESIGN: Qualitative and quantitative research comprising group discussions and questionnaire led interviews with young people accompanied by a self completion questionnaire. SETTINGS: Argyll and Clyde Health Board area, west Scotland. SUBJECTS: Eight groups aged 12-17 years; 824 aged 12-17 recruited by multistage cluster probability sample from the community health index. RESULTS: Young people were familiar with designer drinks, especially MD 20/20 and leading brands of strong white cider. Attitudes towards these drinks varied quite distinctly with age, clearly reflecting their attitudes towards and motivations for drinking in general. The brand imagery of designer drinks-in contrast with that of more mainstream drinks-matched many 14 and 15 year olds' perceptions and expectations of drinking. Popularity of designer drinks peaked between the ages of 13 and 16 while more conventional drinks showed a consistent increase in popularity with age. Consumption of designer drinks tended to be in less controlled circumstances and was associated with heavier alcohol intake and greater drunkenness. CONCLUSIONS: Designer drinks are a cause for concern. They appeal to young people, often more so than conventional drinks, and are particularly attractive to 14-16 year olds. Consumption of designer drinks is also associated with drinking in less controlled environments, heavier drinking, and greater drunkenness. There is a need for policy debate to assess the desirability of these drinks and the extent to which further controls on their marketing are required. PMID:9040387

  7. Azotaemic renal osteodystrophy: a quantitative study on iliac bone.

    PubMed

    Ellis, H A; Peart, K M

    1973-02-01

    The histopathology of bone is described in 60 patients with chronic renal failure due to a variety of renal diseases. Changes of azotaemic renal osteodystrophy included osteitis fibrosa, osteomalacia, and osteosclerosis. Quantitative histology using a point-counting technique revealed a significant increase in total bone, mineralized bone, and osteoid in comparison with a control group of 68 individuals. Osteitis fibrosa due to secondary hyperparathyroidism occurred in 93%, osteomalacia in 40%, and osteosclerosis in 30% of patients. Woven bone formation was a characteristic feature and was related to the severity of osteitis fibrosa. There were significant correlations between the weights of parathyroid glands and the number of osteoclasts, amounts of woven bone, and marrow fibrosis in the ilium. Hyperparathyroidism caused degradation of mineralized bone but the loss was balanced or exceeded by the aggradation of woven mineralized bone. Woven bone formation together with excess osteoid gave rise to osteosclerosis. The histological findings indicate that hyperparathyroidism and osteitis fibrosa usually occur early in chronic renal failure and that osteomalacia develops subsequently.

  8. Quantitative susceptibility mapping of human brain at 3T: a multisite reproducibility study.

    PubMed

    Lin, P-Y; Chao, T-C; Wu, M-L

    2015-03-01

    Quantitative susceptibility mapping of the human brain has demonstrated strong potential in examining iron deposition, which may help in investigating possible brain pathology. This study assesses the reproducibility of quantitative susceptibility mapping across different imaging sites. In this study, the susceptibility values of 5 regions of interest in the human brain were measured on 9 healthy subjects following calibration by using phantom experiments. Each of the subjects was imaged 5 times on 1 scanner with the same procedure repeated on 3 different 3T systems so that both within-site and cross-site quantitative susceptibility mapping precision levels could be assessed. Two quantitative susceptibility mapping algorithms, similar in principle, one by using iterative regularization (iterative quantitative susceptibility mapping) and the other with analytic optimal solutions (deterministic quantitative susceptibility mapping), were implemented, and their performances were compared. Results show that while deterministic quantitative susceptibility mapping had nearly 700 times faster computation speed, residual streaking artifacts seem to be more prominent compared with iterative quantitative susceptibility mapping. With quantitative susceptibility mapping, the putamen, globus pallidus, and caudate nucleus showed smaller imprecision on the order of 0.005 ppm, whereas the red nucleus and substantia nigra, closer to the skull base, had a somewhat larger imprecision of approximately 0.01 ppm. Cross-site errors were not significantly larger than within-site errors. Possible sources of estimation errors are discussed. The reproducibility of quantitative susceptibility mapping in the human brain in vivo is regionally dependent, and the precision levels achieved with quantitative susceptibility mapping should allow longitudinal and multisite studies such as aging-related changes in brain tissue magnetic susceptibility. © 2015 by American Journal of Neuroradiology.

  9. Use of Quantitative Microbial Risk Assessment to Improve Interpretation of a Recreational Water Epidemiological Study

    EPA Science Inventory

    We conducted a supplemental water quality monitoring study and quantitative microbial risk assessment (QMRA) to complement the United States Environmental Protection Agency’s (U.S. EPA) National Epidemiological and Environmental Assessment of Recreational Water study at Boq...

  10. Use of Quantitative Microbial Risk Assessment to Improve Interpretation of a Recreational Water Epidemiological Study

    EPA Science Inventory

    We conducted a supplemental water quality monitoring study and quantitative microbial risk assessment (QMRA) to complement the United States Environmental Protection Agency’s (U.S. EPA) National Epidemiological and Environmental Assessment of Recreational Water study at Boq...

  11. Real-time quantitative phase imaging for cell studies

    NASA Astrophysics Data System (ADS)

    Pham, Hoa Vinh

    Most biological cells are not clearly visible with a bright field microscope. Several methods have been developed to improve contrast in cell imaging, including use of exogenous contrast agents such as fluorescence microscopy, as well as utilizing properties of light-specimen interaction for optics design, to reveal the endogenous contrast, such as phase contrast microscopy (PCM) and differential interference contrast (DIC) microscopy. Although PCM and DIC methods significantly improve the image contrast without the need for staining agents, they only provide qualitative information about the phase change induced by the cells as light passes through them. Quantitative phase imaging (QPI) has recently emerged as an effective imaging tool which provides not only better image contrast but also cell-induced phase shifts in the optical pathlength, thus allowing nanometer-scale measurements of structures and dynamics of the cells. Other important aspects of an imaging system are its imaging speed and throughput. High-throughput, high-speed, real-time quantitative phase imaging with high spatial and temporal sensitivity is highly desirable in many applications including applied physics and biomedicine. In this dissertation, to address this need, I discuss the development of such an imaging system that includes the white light diffraction phase microscopy (wDPM), a new optical imaging method, and image reconstruction/analysis algorithms using graphics processing units (GPUs). wDPM can measure optical pathlength changes at nanometer scale both spatially and temporally with single-shot image acquisition, enabling very fast imaging. I also exploit the broadband spectrum of white light used as the light source in wDPM to develop a system called spectroscopic diffraction phase microscopy (sDPM). This sDPM system allows QPI measurements at several wavelengths, which solves the problem of thickness and refractive index coupling in the phase shifts induced by the cell, and which

  12. Bibliometric approach of factors affecting scientific productivity in environmental sciences and ecology.

    PubMed

    Dragos, Cristian Mihai; Dragos, Simona Laura

    2013-04-01

    Different academic bibliometric studies have measured the influence of economic, political and linguistic factors in the academic output of countries. Separate analysis in different fields can reveal specific incentive factors. Our study proves that the Environmental Performance Index, computed by Yale University, is highly significant (p<0.01) for the productivity of research and development activities in environmental sciences and ecology. The control variables like education financing, publishing of ISI Thomson domestic journals and the English language are also significant. The methodology uses Ordinary Least Squares multiple regressions with convincing results (R(2)=0.752). The relative positions of the 92 countries in the sample are also discussed. We draw up a ranking of the countries' concern for the environment, considering evenly the scientific productivity and the environment quality. We notice huge differences concerning the number of inhabitants and population income between the countries that dominate the classification and those occupying the last positions.

  13. Erosion of Terrestrial Rift Flank Topography: A Quantitative Study

    NASA Technical Reports Server (NTRS)

    Weissel, Jeffrey K.

    1999-01-01

    Many rifted or passive continental margins feature a seaward-facing erosional escarpment which abruptly demarcates deeply weathered, low relief, interior uplands from a deeply incised, high relief coastal zone. It is generally accepted that these escarpments originate at the time of continental rifting and propagate inland through the elevated rift flank topography at rates on the order of 1 km/Myr over the course of a margin's history. Considering the length of passive margins worldwide and an average rift flank plateau height of several hundred meters, it is clear that sediment eroded from passive margins is an important component of the mass flux from continents to oceans through geologic time. The overall goal of the research reported here is to develop a quantitative understanding of the kinematics of escarpment propagation across passive margins and the underlying geological processes responsible for this behavior. Plateau-bounding escarpments in general exhibit two basic forms depending on the direction of surface water drainage on the plateau interior relative to the escarpment. Where surface water flows away from the escarpment, the escarpment takes the form of subdued embayments and promontories, such that its overall trend remains fairly straight as it evolves with time. Where upland streams flow across the escarpment, it takes the form of dramatic, narrow gorges whose heads appear to propagate up the plateau drainage systems as large-scale knickpoints. From work on the Colorado Plateau, Schmidt (1987) noted that the Colorado River is located much closer to the Grand Canyon's south rim, a drainage divide escarpment, than to the north rim, which is a gorge-like escarpment. The main implication is that the gorge-like form might be associated with higher long-term average erosion rates compared to the drainage divide escarpment type.

  14. HIV-envelope-dependent cell-cell fusion: quantitative studies.

    PubMed

    Huerta, Leonor; López-Balderas, Nayali; Rivera-Toledo, Evelyn; Sandoval, Guadalupe; Gómez-Icazbalceta, Guillermo; Villarreal, Carlos; Lamoyi, Edmundo; Larralde, Carlos

    2009-08-11

    Interaction in vitro between cells infected with human immunodeficiency virus (HIV) and surrounding, uninfected, target cells often leads to cell fusion and the formation of multinucleated cells, called syncytia. The presence in HIV-infected individuals of virus strains able to induce syncytia in cultures of T cells is associated with disease progression and AIDS. Even in the asymptomatic stage of infection, multinucleated cells have been observed in different organs, indicating that fused cells may be generated and remain viable in the tissues of patients. We used lymphocytic cells transfected for the expression of the HIV-envelope (Env) glycoproteins to develop a method for the direct quantification of fusion events by flow cytometry (Huerta et al., 2006, J. Virol. Methods 138, 17-23; López-Balderas et al., 2007, Virus Res. 123, 138-146). The method involves the staining of fusion partners with lipophilic probes and the use of fluorescence resonance energy transfer (FRET) to distinguish between fused and aggregated cells. We have shown that such a flow-cytometry assay is appropriate for the screening of compounds that have the potential to modulate HIV-Env-mediated cell fusion. Even those syncytia that are small or few in numbers can be detected. Quantitative analysis of the fusion products was performed with this technique; the results indicated that the time of reaction and initial proportion of fusion partners determine the number, relative size, and average cellular composition of syncytia. Heterogeneity of syncytia generated by HIV-Env-mediated cell-cell fusion may result in a variety of possible outcomes that, in turn, may influence the biological properties of the syncytia and surrounding cells, as well as replication of virus. Given the myriad immune abnormalities leading to AIDS, the full understanding of the extent, diverse composition, and role of fused cells in the pathogenesis of, and immune response to, HIV infection is an important, pending issue.

  15. A Bibliometric Analysis of PubMed Literature on Middle East Respiratory Syndrome.

    PubMed

    Wang, Zhengting; Chen, Yongdi; Cai, Gaofeng; Jiang, Zhenggang; Liu, Kui; Chen, Bin; Jiang, Jianmin; Gu, Hua

    2016-06-13

    Middle East Respiratory Syndrome (MERS), a pandemic threat to human beings, has aroused huge concern worldwide, but no bibliometric studies have been conducted on MERS research. The aim of this study was to map research productivity on the disease based on the articles indexed in PubMed. The articles related to MERS dated from 2012 to 2015 were retrieved from PubMed. The articles were classified into three categories according to their focus. Publication outputs were assessed and frequently used terms were mapped using the VOS viewer software. A total of 443 articles were included for analysis. They were published in 162 journals, with Journal of Virology being the most productive (44 articles; 9.9%) and by six types of organizations, with universities being the most productive (276 articles; 62.4%).The largest proportion of the articles focused on basic medical sciences and clinical studies (47.2%) and those on prevention and control ranked third (26.2%), with those on other focuses coming in between (26.6%). The articles on prevention and control had the highest mean rank for impact factor (IF) (226.34), followed by those on basic medical sciences and clinical studies (180.23) and those on other focuses (168.03). The mean rank differences were statistically significant (p = 0.000). Besides, "conronavirus", "case", "transmission" and "detection" were found to be the most frequently used terms. The findings of this first bibliometric study on MERS suggest that the prevention and control of the disease has become a big concern and related research should be strengthened.

  16. A Bibliometric Analysis of PubMed Literature on Middle East Respiratory Syndrome

    PubMed Central

    Wang, Zhengting; Chen, Yongdi; Cai, Gaofeng; Jiang, Zhenggang; Liu, Kui; Chen, Bin; Jiang, Jianmin; Gu, Hua

    2016-01-01

    Middle East Respiratory Syndrome (MERS), a pandemic threat to human beings, has aroused huge concern worldwide, but no bibliometric studies have been conducted on MERS research. The aim of this study was to map research productivity on the disease based on the articles indexed in PubMed. The articles related to MERS dated from 2012 to 2015 were retrieved from PubMed. The articles were classified into three categories according to their focus. Publication outputs were assessed and frequently used terms were mapped using the VOS viewer software. A total of 443 articles were included for analysis. They were published in 162 journals, with Journal of Virology being the most productive (44 articles; 9.9%) and by six types of organizations, with universities being the most productive (276 articles; 62.4%).The largest proportion of the articles focused on basic medical sciences and clinical studies (47.2%) and those on prevention and control ranked third (26.2%), with those on other focuses coming in between (26.6%). The articles on prevention and control had the highest mean rank for impact factor (IF) (226.34), followed by those on basic medical sciences and clinical studies (180.23) and those on other focuses (168.03). The mean rank differences were statistically significant (p = 0.000). Besides, “conronavirus”, “case”, “transmission” and “detection” were found to be the most frequently used terms. The findings of this first bibliometric study on MERS suggest that the prevention and control of the disease has become a big concern and related research should be strengthened. PMID:27304963

  17. Bibliometric analysis of medicine-related publications on poverty (2005-2015).

    PubMed

    Sweileh, Waleed M; Al-Jabi, Samah W; Sawalha, Ansam F; AbuTaha, Adham S; Zyoud, Sa'ed H

    2016-01-01

    Poverty is a global problem. The war against poverty requires not only financial support, but also poverty-related research to pinpoint areas of high need of intervention. In line with international efforts to fight poverty and negative consequences, we carried out this study to give a bibliometric overview of medicine-related literature on poverty. Such a s study is an indicator of the extent of interaction of various international key players on the war against poverty-related health problems. Scopus was used to achieve the objective of this study. The time span set for this study was 2005-2015. Poverty-related articles under the subject area "Medicine" were used to give bibliometric indicators such as annual growth of publications, international collaboration, highly cited articles, active countries, institutions, journals, and authors. The total number of retrieved articles was 1583. The Hirsh-index of retrieved articles was 56. A modest and fluctuating increase was seen over the study period. Visualization map of retrieved articles showed that "HIV", infectious diseases, mental health, India, and Africa were most commonly encountered terms. No significant dominance of any particular author or journal was observed in retrieved articles. The United States of America had the largest share in the number of published articles. The World Health Organization and Centers for Disease Prevention and Control were among top active institutions/organizations. International collaboration was observed in less than one third of publications. Top cited articles focused on three poverty-related health issues, mainly, infectious diseases, malnutrition, and child development/psychology. Most of top articles were published in high impact journals. Data indicated that articles on poverty were published in high influential medical journals indicative of the importance of poverty as a global health problem. However, the number publications and the extent of international

  18. A Kernel-based Account of Bibliometric Measures

    NASA Astrophysics Data System (ADS)

    Ito, Takahiko; Shimbo, Masashi; Kudo, Taku; Matsumoto, Yuji

    The application of kernel methods to citation analysis is explored. We show that a family of kernels on graphs provides a unified perspective on the three bibliometric measures that have been discussed independently: relatedness between documents, global importance of individual documents, and importance of documents relative to one or more (root) documents (relative importance). The framework provided by the kernels establishes relative importance as an intermediate between relatedness and global importance, in which the degree of `relativity,' or the bias between relatedness and importance, is naturally controlled by a parameter characterizing individual kernels in the family.

  19. Scientific research in malaria: bibliometric assessment of the Latin-American contributions.

    PubMed

    Munoz-Urbano, Marcela; Lopez-Isaza, Andres F; Hurtado-Hurtado, Natalia; Gomez-Suta, Daniela; Murillo-Abadia, Jonathan; Delgado-Osorio, Nathalia; Lagos-Grisales, Guillermo J; Villegas, Soraya; Medina-Morales, Diego A; Rodriguez-Morales, Alfonso J

    2014-01-01

    Malaria is a parasitic disease of high global impact in public health, including Latin America. There should be more researched, particularly in this region. A bibliometric assessment of the Latin American contributions about malaria was done. Bibliometric study at SCI (1980-2013), MEDLINE/ GOPUBMED (1802-2013), Scopus (1959-2013), SCIELO (2004-2013), LILACS (1980-2013). The studies were characterized by study type, year of publication, city/country of origin, journals and more productive authors, citations and H index. At SCI, 2,806 articles were retrieved (5.13% of the total). Brazil was the highest producer (31.41%), followed by Colombia (14.3%) and Mexico (9.5%). The region received 39,894 citations, 32.2% from Brazil (H index=51), 12.75% Mexico (H index=38), 11.2% Colombia (H index=33). At Scopus, there are 4,150 articles (4.9% of the total), 33.0% Brazil, 11.3% Colombia and 8.8% Mexico; 17% in Brazil were from Universidad de São Paulo; 23.6% of Colombia from Universidad de Antioquia; 15.4% of Mexico from Instituto Nacional de Salud Pública. At Medline there were 4,278 records (36.8% Brazil). At SciELO there are 792 records (45.3% Brazil). At LILACS there were 1744 records (34.3% Brazil). Brazil has the highest output of the region, as Venezuela the scientific production in Malaria was related with the burden of disease. This was not the case for Colombia. Scientific production at bibliographical databases, particularly regionals, is low, compared to the high incidence of this disease that requires more research and control.

  20. Content and bibliometric analyses of the Journal of Manual & Manipulative Therapy

    PubMed Central

    Simon, Corey B; Coronado, Rogelio A; Wurtzel, Wendy A; Riddle, Daniel L; George, Steven Z

    2014-01-01

    Background: Article characteristics and trends have been elucidated for other physical therapy-focused journals using content and bibliometric analysis. These findings are important for assessing the current state of a journal and for guiding future publication of research. To date, these analyses have not been performed for the Journal of Manual & Manipulative Therapy (JMMT). Objective: To describe content and trends for articles published in JMMT over a 20-year period (1993–2012). Methods: Journal articles were coded using previously-established domains (article type, participant type, research design, study purpose, and clinical condition). Total publications and proportion of publications based on domain were described. Articles specific to manual therapy intervention were examined and compared to data from other physical therapy-focused journals. Impact by citation and author was examined using bibliometric software. Results: Journal of Manual & Manipulative Therapy was found to have a recent acceleration in the number of articles published annually. Over time, topical reviews have decreased in favor of research reports. However, rigorous study designs have represented only a small portion of total journal content, and case reports have maintained a consistent publication presence. Manual therapy intervention articles in JMMT are predominantly case designs, however are similar in characteristics to manual therapy intervention articles published in other physical therapy-focused journals. For JMMT articles overall and manual therapy intervention articles across journals, young to middle-aged symptomatic adults with low back and/or neck pain were the most common study participants. Discussion: Increases in the number of papers and a move toward research reports were observed in JMMT over the 20-year period. Considerations for the future were outlined, including the publication of articles with more rigorous research designs. Manual therapy research for

  1. Internet of Things in Health Trends Through Bibliometrics and Text Mining.

    PubMed

    Konstantinidis, Stathis Th; Billis, Antonis; Wharrad, Heather; Bamidis, Panagiotis D

    2017-01-01

    Recently a new buzzword has slowly but surely emerged, namely the Internet of Things (IoT). The importance of IoT is identified worldwide both by organisations and governments and the scientific community with an incremental number of publications during the last few years. IoT in Health is one of the main pillars of this evolution, but limited research has been performed on future visions and trends. Thus, in this study we investigate the longitudinal trends of Internet of Things in Health through bibliometrics and use of text mining. Seven hundred seventy eight (778) articles were retrieved form The Web of Science database from 1998 to 2016. The publications are grouped into thirty (30) clusters based on abstract text analysis resulting into some eight (8) trends of IoT in Health. Research in this field is obviously obtaining a worldwide character with specific trends, which are worth delineating to be in favour of some areas.

  2. A bibliometric analysis of research on the behavior therapy in China and its trend.

    PubMed

    Zhao, Shanming; Neng, Changhua; Wu, Hanrong

    2003-01-01

    To get formed of the status of research and application of the domestic behavior therapy and its development trend, the time distribution and the subject distribution were bibliometrically analyzed of the literature on behavior therapy from 1981 to 2000 in the CBMdisc. Our results showed that the number of literature of behavior therapy has been increasing in exponential manner over the past 20 years; the behavior modification, the biofeedback and the cognitive therapy are extensively used in China. In clinical practice, the behavior modification and the biofeedback have been applied in all departments of medical institutions, especially for treating the cardiovascular and the neurological conditions. The cognitive therapy has been employed mainly for the treatment of mental disorders (or dysphrenia), the aversive therapy mainly for material withdrawal, and the systematic desensitization for phobia. There was no report found on the clinical use of meditation. It is concluded that the study and application in behavior therapy in China is currently developing very fast.

  3. [Good and bad uses of the Impact Factor, a bibliometric tool].

    PubMed

    Sculier, J P

    2004-02-01

    The Impact Factor (IF) is a bibliometric tool that has become very popular among the academic people. It has been developed by the publishers of scientific reviews to determine the impact of their journal among the scientific and medical community. It is based on the following principle: more often are cited the articles of a journal, more often is that journal read and thus sold. Various secondary applications have been performed with the IF, including the evaluation of the academic curriculum of a scientist or of a research group. That approach is however not validated, a recent methodological study having demonstrated a lack of good correlation between the IF of a given review and the quality scores of its published articles.

  4. The emerging science of quantitative imaging biomarkers terminology and definitions for scientific studies and regulatory submissions.

    PubMed

    Kessler, Larry G; Barnhart, Huiman X; Buckler, Andrew J; Choudhury, Kingshuk Roy; Kondratovich, Marina V; Toledano, Alicia; Guimaraes, Alexander R; Filice, Ross; Zhang, Zheng; Sullivan, Daniel C

    2015-02-01

    The development and implementation of quantitative imaging biomarkers has been hampered by the inconsistent and often incorrect use of terminology related to these markers. Sponsored by the Radiological Society of North America, an interdisciplinary group of radiologists, statisticians, physicists, and other researchers worked to develop a comprehensive terminology to serve as a foundation for quantitative imaging biomarker claims. Where possible, this working group adapted existing definitions derived from national or international standards bodies rather than invent new definitions for these terms. This terminology also serves as a foundation for the design of studies that evaluate the technical performance of quantitative imaging biomarkers and for studies of algorithms that generate the quantitative imaging biomarkers from clinical scans. This paper provides examples of research studies and quantitative imaging biomarker claims that use terminology consistent with these definitions as well as examples of the rampant confusion in this emerging field. We provide recommendations for appropriate use of quantitative imaging biomarker terminological concepts. It is hoped that this document will assist researchers and regulatory reviewers who examine quantitative imaging biomarkers and will also inform regulatory guidance. More consistent and correct use of terminology could advance regulatory science, improve clinical research, and provide better care for patients who undergo imaging studies.

  5. Public health research in India in the new millennium: a bibliometric analysis

    PubMed Central

    Kalita, Anuska; Shinde, Sachin; Patel, Vikram

    2015-01-01

    Background Public health research has gained increasing importance in India's national health policy as the country seeks to address the high burden of disease and its inequitable distribution, and embarks on an ambitious agenda towards universalising health care. Objective This study aimed at describing the public health research output in India, its focus and distribution, and the actors involved in the research system. It makes recommendations for systematically promoting and strengthening public health research in the country. Design The study was a bibliometric analysis of PubMed and IndMed databases for years 2000–2010. The bibliometric data were analysed in terms of biomedical focus based on the Global Burden of Disease, location of research, research institutions, and funding agencies. Results A total of 7,893 eligible articles were identified over the 11-year search period. The annual research output increased by 42% between 2000 and 2010. In total, 60.8% of the articles were related to communicable diseases, newborn, maternal, and nutritional causes, comparing favourably with the burden of these causes (39.1%). While the burdens from non-communicable diseases and injuries were 50.2 and 10.7%, respectively, only 31.9 and 7.5% of articles reported research for these conditions. The north-eastern states and the Empowered-Action-Group states of India were the most under-represented for location of research. In total, 67.2% of papers involved international collaborations and 49.2% of these collaborations were with institutions in the UK or USA; 35.4% of the publications involved international funding and 71.2% of funders were located in the UK or USA. Conclusions While public health research output in India has increased significantly, there are marked inequities in relation to the burden of disease and the geographic distribution of research. Systematic priority setting, adequate funding, and institutional capacity building are needed to address these

  6. [Bibliometric map of research done in primary care in Spain during the period 2008-2012].

    PubMed

    López-Torres Hidalgo, Jesús; Basora Gallisà, Josep; Orozco Beltrán, Domingo; Bellón Saameño, Juan Ángel

    2014-12-01

    To describe the Spanish scientific production of primary care during 2008-2012. Observational study bibliometric. Spanish scientific production in primary care. The study focused on publications indexed in Medline. In each record was obtained journal, year of publication, first/last author, workplace and autonomous community. Later, articles were classified according to their content or areas of research. The impact factor was obtained from the basis of bibliometric analysis Journal Citation Reports. Using search criteria, were selected 1,048 documents. The transiency rate was 62.6%. Production increased from 170 papers in 2008 to 291 in 2012. Most (65.7%) came from health centers, but we observed a significant increase (P=.01) of the articles from units or research institutes (5.9% in 2008, 12.0% in 2012). Of the total, 61.6% were classified as «clinical aspects», 22.5% were published in the journal Atención Primaria, 80.5% in journals with impact factor and 33.49% in foreign journals, being higher this proportion (P<.001) in units or research institutes (70.5% vs. 29.8%). In relation to population (articles/100.000 inhab.), the most productive communities were Cataluña (4.1), Castilla-La Mancha (3.6), Aragón (3.4) and Navarra (3.4). In primary care publications there is great diversity in both research areas such as in journals where published. Most are from health centers, treat clinical aspects and published in Spanish journals. Differences in the volume of scientific production between regions are observed. Copyright © 2013 Elsevier España, S.L.U. All rights reserved.

  7. Global trends of municipal solid waste research from 1997 to 2014 using bibliometric analysis.

    PubMed

    Chen, Haibin; Jiang, Wei; Yang, Yu; Yang, Yan; Man, Xin

    2015-10-01

    This study uses a bibliometric approach to identify global trends related to the municipal solid waste (MSW). It applies related literature in the Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Conference Proceedings Citation Index - Science (CPCI-S) and Conference Proceedings Citation Index - Social Science & Humanities (CPCI-SSH), retrieved from the ISI Web of Science. The data used covers the period from 1997 to 2014. Analyzed aspects included document type, and publication output as well as distribution of journals, subject category, countries, institutions, title-words, author keywords, and keywords plus. An evaluating indicator, citation score, was applied to characterize the MSW publications. The research outputs of MSW had steadily increased in the field of energy fuels, engineering chemical and biotechnology applied microbiology, especially environmental sciences and engineering environmental. The predominance of Chinese institutions in terms of article count and a predominance of industrialized countries' institutions in terms of citation score were compared. Finally, author keywords, words in title, and keywords plus were analyzed to provide research emphasis, with the developing trends and recent hotspots provided. A systematic overview of scientific literature dealing with municipal solid waste (MSW) is provided by a bibliometric analysis. The analysis of author keywords helps in drawing the research trends in a special perspective. Research studies on food waste, life cycle assessment (LCA), and renewable energy tend to be a new research focus in the area of MSW. The conclusions could provide a reference to the decision making and policy of MSW management for the government to some extent.

  8. Assessing urology and nephrology research activity in Arab countries using ISI web of science bibliometric database.

    PubMed

    Sweileh, Waleed M; Zyoud, Sa'ed H; Al-Jabi, Samah W; Sawalha, Ansam F

    2014-04-23

    Bibliometric analysis is increasingly being used for research assessment. The main objective of this study was to assess research output in Urology and Nephrology subject from the Arab countries. Original scientific articles or reviews published from the 21 Arab countries in "Urology and Nephrology" subject were screened using the ISI Web of Science database. Research productivity was evaluated based on a methodology developed and used in other bibliometric studies by analyzing the annual productivity, names of journals, citations; top 10 active institution and authors as well as country contribution to Urology and Nephrology research. Three thousand and seventy six documents in "urology and nephrology" subject category were retrieved from 104 journals. This represents 1.4% of the global research output in "urology and nephrology". Four hundred and two documents (12.66%) were published in Annales D Urologie Journal. The h-index of the retrieved documents was 57. The total number of citations, at the time of data analysis, was 30401 with an average citation of 9.57 per document. Egypt, with a total publication of 1284 (40.43%) ranked first among the Arab countries in "urology and nephrology" subject category. Mansoura University in Egypt was the most productive institution with a total of 561 (15.33%) documents. Arab researchers collaborated most with researchers from the United States of America (226; 7.12%) in urology and nephrology research. The present data reveals a good contribution of some Arab countries to the field of "urology and nephrology". More efforts are needed by some other Arab countries to bridge the gap in urology and nephrology research. Overall, the quality of urology/nephrology research is considered relatively high as measured by h-index. Cooperation in urology/nephrology research should be encouraged in the Arab world to bridge the gap with that from developed countries.

  9. Assessing urology and nephrology research activity in Arab countries using ISI web of science bibliometric database

    PubMed Central

    2014-01-01

    Background Bibliometric analysis is increasingly being used for research assessment. The main objective of this study was to assess research output in Urology and Nephrology subject from the Arab countries. Original scientific articles or reviews published from the 21 Arab countries in “Urology and Nephrology” subject were screened using the ISI Web of Science database. Research productivity was evaluated based on a methodology developed and used in other bibliometric studies by analyzing the annual productivity, names of journals, citations; top 10 active institution and authors as well as country contribution to Urology and Nephrology research. Results Three thousand and seventy six documents in “urology and nephrology” subject category were retrieved from 104 journals. This represents 1.4% of the global research output in “urology and nephrology”. Four hundred and two documents (12.66%) were published in Annales D Urologie Journal. The h-index of the retrieved documents was 57. The total number of citations, at the time of data analysis, was 30401 with an average citation of 9.57 per document. Egypt, with a total publication of 1284 (40.43%) ranked first among the Arab countries in “urology and nephrology” subject category. Mansoura University in Egypt was the most productive institution with a total of 561 (15.33%) documents. Arab researchers collaborated most with researchers from the United States of America (226; 7.12%) in urology and nephrology research. Conclusion The present data reveals a good contribution of some Arab countries to the field of “urology and nephrology”. More efforts are needed by some other Arab countries to bridge the gap in urology and nephrology research. Overall, the quality of urology/nephrology research is considered relatively high as measured by h-index. Cooperation in urology/nephrology research should be encouraged in the Arab world to bridge the gap with that from developed countries. PMID:24758477

  10. Correction: Understanding metal homeostasis in primary cultured neurons. Studies using single neuron subcellular and quantitative metallomics.

    PubMed

    Colvin, Robert A; Lai, Barry; Holmes, William R; Lee, Daewoo

    2015-09-01

    Correction for 'Understanding metal homeostasis in primary cultured neurons. Studies using single neuron subcellular and quantitative metallomics' by Robert A. Colvin et al., Metallomics, 2015, 7, 1111-1123.

  11. Assessing the reporting of categorised quantitative variables in observational epidemiological studies.

    PubMed

    Mabikwa, Onkabetse V; Greenwood, Darren C; Baxter, Paul D; Fleming, Sarah J

    2017-03-14

    One aspect to consider when reporting results of observational studies in epidemiology is how quantitative risk factors are analysed. The STROBE (Strengthening the Reporting of Observational Studies in Epidemiology) guidelines recommend that researchers describe how they handle quantitative variables when analysing data. For categorised quantitative variables, the authors are required to provide reasons and justifications informing their practice. We investigated and assessed the practices and reporting of categorised quantitative variables in epidemiology. The assessment was based on five medical journals that publish epidemiological research. Observational studies published between April and June 2015 and investigating the relationships between quantitative exposures (or risk factors) and the outcomes were considered for assessment. A standard form was used to collect the data, and the reporting patterns amongst eligible studies were quantified and described. Out of 61 articles assessed for eligibility, 23 observational studies were included in the assessment. Categorisation of quantitative exposures occurred in 61% of these studies and reasons informing the practice were rarely provided. Only one article explained the choice of categorisation in the analysis. Transformation of quantitative exposures into four or five groups was common and dominant amongst studies using equally spaced categories. Dichotomisation was not popular; the practice featured in one article. Overall, the majority (86%) of the studies preferred ordered or arbitrary group categories. Other criterions used to decide categorical boundaries were based on established guidelines such as consensus statements and WHO standards. Categorisation of continuous variables remains a dominant practice in epidemiological studies. The reasons informing the practice of categorisation within published work are limited and remain unknown in most articles. The existing STROBE guidelines could provide stronger

  12. Interactions among Online Learners: A Quantitative Interdisciplinary Study

    ERIC Educational Resources Information Center

    Jain, Pawan; Jain, Sachin; Jain, Smita

    2011-01-01

    This study concerns the design and development of online instruction and specifically targets interaction and communication between online learners. Facilitating appropriate and meaningful interactions in designing instruction is a major goal for anyone developing a course, especially an online class. The data for this study came from the online…

  13. Quantitative evaluation of wrist posture and typing performance: A comparative study of 4 computer keyboards

    SciTech Connect

    Burastero, S.

    1994-05-01

    The present study focuses on an ergonomic evaluation of 4 computer keyboards, based on subjective analyses of operator comfort and on a quantitative analysis of typing performance and wrist posture during typing. The objectives of this study are (1) to quantify differences in the wrist posture and in typing performance when the four different keyboards are used, and (2) to analyze the subjective preferences of the subjects for alternative keyboards compared to the standard flat keyboard with respect to the quantitative measurements.

  14. Bibliometric analysis of the scientific production in the area of Optometry.

    PubMed

    Povedano Montero, F J; López-Muñoz, F; Hidalgo Santa Cruz, F

    2016-04-01

    Using a bibliometric approach an analysis was made of the scientific publications of Spanish investigators in the area of optometry, from 1974 until 2013. The EMBASE database was used for this study, employing optomtr*, optic*, visual, vision, eye*, and ophthalm* as search terms. The most common bibliometric indicators were applied for the selected publications. The number of published articles retrieved for Spain from 1974-2013 was 1,055. The growth of publications was more exponential (R=0.93) than linear (R= 0.71). The doubling time of scientific production was 3.63 years. The level of productivity primarily corresponded to small producers (Transience index of 64%). The collaboration index was 4.4 authors per paper. The majority of the output was generated in academic settings (62.27%). The Bradford core was formed by four journals, in which Optometry and Vision Science accounted for the majority of publications, with 11.85%. Research in the area of optometry in Spain is in a phase of exponential growth, containing a high level of transient authors, which may indicate either a low productivity or the presence of investigators from other related fields that have published in a sporadic manner in this area. A small number of research groups are responsible for producing the majority of articles, primarily in an academic setting. There is a high concentration of publications in a few journals. Copyright © 2015 Sociedad Española de Oftalmología. Published by Elsevier España, S.L.U. All rights reserved.

  15. Type 2 Diabetes Research Yield, 1951-2012: Bibliometrics Analysis and Density-Equalizing Mapping

    PubMed Central

    Geaney, Fiona; Scutaru, Cristian; Kelly, Clare; Glynn, Ronan W.; Perry, Ivan J.

    2015-01-01

    The objective of this paper is to provide a detailed evaluation of type 2 diabetes mellitus research output from 1951-2012, using large-scale data analysis, bibliometric indicators and density-equalizing mapping. Data were retrieved from the Science Citation Index Expanded database, one of the seven curated databases within Web of Science. Using Boolean operators "OR", "AND" and "NOT", a search strategy was developed to estimate the total number of published items. Only studies with an English abstract were eligible. Type 1 diabetes and gestational diabetes items were excluded. Specific software developed for the database analysed the data. Information including titles, authors’ affiliations and publication years were extracted from all files and exported to excel. Density-equalizing mapping was conducted as described by Groenberg-Kloft et al, 2008. A total of 24,783 items were published and cited 476,002 times. The greatest number of outputs were published in 2010 (n=2,139). The United States contributed 28.8% to the overall output, followed by the United Kingdom (8.2%) and Japan (7.7%). Bilateral cooperation was most common between the United States and United Kingdom (n=237). Harvard University produced 2% of all publications, followed by the University of California (1.1%). The leading journals were Diabetes, Diabetologia and Diabetes Care and they contributed 9.3%, 7.3% and 4.0% of the research yield, respectively. In conclusion, the volume of research is rising in parallel with the increasing global burden of disease due to type 2 diabetes mellitus. Bibliometrics analysis provides useful information to scientists and funding agencies involved in the development and implementation of research strategies to address global health issues. PMID:26208117

  16. Type 2 Diabetes Research Yield, 1951-2012: Bibliometrics Analysis and Density-Equalizing Mapping.

    PubMed

    Geaney, Fiona; Scutaru, Cristian; Kelly, Clare; Glynn, Ronan W; Perry, Ivan J

    2015-01-01

    The objective of this paper is to provide a detailed evaluation of type 2 diabetes mellitus research output from 1951-2012, using large-scale data analysis, bibliometric indicators and density-equalizing mapping. Data were retrieved from the Science Citation Index Expanded database, one of the seven curated databases within Web of Science. Using Boolean operators "OR", "AND" and "NOT", a search strategy was developed to estimate the total number of published items. Only studies with an English abstract were eligible. Type 1 diabetes and gestational diabetes items were excluded. Specific software developed for the database analysed the data. Information including titles, authors' affiliations and publication years were extracted from all files and exported to excel. Density-equalizing mapping was conducted as described by Groenberg-Kloft et al, 2008. A total of 24,783 items were published and cited 476,002 times. The greatest number of outputs were published in 2010 (n=2,139). The United States contributed 28.8% to the overall output, followed by the United Kingdom (8.2%) and Japan (7.7%). Bilateral cooperation was most common between the United States and United Kingdom (n=237). Harvard University produced 2% of all publications, followed by the University of California (1.1%). The leading journals were Diabetes, Diabetologia and Diabetes Care and they contributed 9.3%, 7.3% and 4.0% of the research yield, respectively. In conclusion, the volume of research is rising in parallel with the increasing global burden of disease due to type 2 diabetes mellitus. Bibliometrics analysis provides useful information to scientists and funding agencies involved in the development and implementation of research strategies to address global health issues.

  17. Breast cancer research output, 1945-2008: a bibliometric and density-equalizing analysis

    PubMed Central

    2010-01-01

    Introduction Breast cancer is the most common form of cancer among women, with an estimated 194,280 new cases diagnosed in the United States in 2009 alone. The primary aim of this work was to provide an in-depth evaluation of research yield in breast cancer from 1945 to 2008, using large-scale data analysis, the employment of bibliometric indicators of production and quality, and density-equalizing mapping. Methods Data were retrieved from the Web of Science (WOS) Science Citation Expanded database; this was searched using the Boolean operator, 'OR', with different terms related to breast cancer, including "breast cancer", "mammary ductal carcinoma" and "breast tumour". Data were then extracted from each file, transferred to Excel charts and visualised as diagrams. Mapping was performed as described by Groneberg-Kloft et al. in 2008. Results A total of 180,126 breast cancer-associated items were produced over the study period; these had been cited 4,136,224 times. The United States returned the greatest level of output (n = 77,101), followed by the UK (n = 18,357) and Germany (n = 12,529). International cooperation peaked in 2008, with 3,127 entries produced as a result; relationships between the United States and other countries formed the basis for the 10 most common forms of bilateral cooperation. Publications from nations with high levels of international cooperation were associated with greater average citation rates. A total of 4,096 journals published at least one item on breast cancer, although the top 50 most prolific titles together accounted for over 43% (77,517/180,126) of the total output. Conclusions Breast cancer-associated research output continues to increase annually. In an era when bibliometric indicators are increasingly being employed in performance assessment, these findings should provide useful information for those tasked with improving that performance. PMID:21176219

  18. Mapping patient safety: a large-scale literature review using bibliometric visualisation techniques

    PubMed Central

    Rodrigues, S P; van Eck, N J; Waltman, L; Jansen, F W

    2014-01-01

    Background The amount of scientific literature available is often overwhelming, making it difficult for researchers to have a good overview of the literature and to see relations between different developments. Visualisation techniques based on bibliometric data are helpful in obtaining an overview of the literature on complex research topics, and have been applied here to the topic of patient safety (PS). Methods On the basis of title words and citation relations, publications in the period 2000–2010 related to PS were identified in the Scopus bibliographic database. A visualisation of the most frequently cited PS publications was produced based on direct and indirect citation relations between publications. Terms were extracted from titles and abstracts of the publications, and a visualisation of the most important terms was created. The main PS-related topics studied in the literature were identified using a technique for clustering publications and terms. Results A total of 8480 publications were identified, of which the 1462 most frequently cited ones were included in the visualisation. The publications were clustered into 19 clusters, which were grouped into three categories: (1) magnitude of PS problems (42% of all included publications); (2) PS risk factors (31%) and (3) implementation of solutions (19%). In the visualisation of PS-related terms, five clusters were identified: (1) medication; (2) measuring harm; (3) PS culture; (4) physician; (5) training, education and communication. Both analysis at publication and term level indicate an increasing focus on risk factors. Conclusions A bibliometric visualisation approach makes it possible to analyse large amounts of literature. This approach is very useful for improving one's understanding of a complex research topic such as PS and for suggesting new research directions or alternative research priorities. For PS research, the approach suggests that more research on implementing PS improvement initiatives

  19. Mapping patient safety: a large-scale literature review using bibliometric visualisation techniques.

    PubMed

    Rodrigues, S P; van Eck, N J; Waltman, L; Jansen, F W

    2014-03-13

    The amount of scientific literature available is often overwhelming, making it difficult for researchers to have a good overview of the literature and to see relations between different developments. Visualisation techniques based on bibliometric data are helpful in obtaining an overview of the literature on complex research topics, and have been applied here to the topic of patient safety (PS). On the basis of title words and citation relations, publications in the period 2000-2010 related to PS were identified in the Scopus bibliographic database. A visualisation of the most frequently cited PS publications was produced based on direct and indirect citation relations between publications. Terms were extracted from titles and abstracts of the publications, and a visualisation of the most important terms was created. The main PS-related topics studied in the literature were identified using a technique for clustering publications and terms. A total of 8480 publications were identified, of which the 1462 most frequently cited ones were included in the visualisation. The publications were clustered into 19 clusters, which were grouped into three categories: (1) magnitude of PS problems (42% of all included publications); (2) PS risk factors (31%) and (3) implementation of solutions (19%). In the visualisation of PS-related terms, five clusters were identified: (1) medication; (2) measuring harm; (3) PS culture; (4) physician; (5) training, education and communication. Both analysis at publication and term level indicate an increasing focus on risk factors. A bibliometric visualisation approach makes it possible to analyse large amounts of literature. This approach is very useful for improving one's understanding of a complex research topic such as PS and for suggesting new research directions or alternative research priorities. For PS research, the approach suggests that more research on implementing PS improvement initiatives might be needed.

  20. Substance use disorders in Arab countries: research activity and bibliometric analysis

    PubMed Central

    2014-01-01

    Background Substance use disorders, which include substance abuse and substance dependence, are present in all regions of the world including Middle Eastern Arab countries. Bibliometric analysis is an increasingly used tool for research assessment. The main objective of this study was to assess research productivity in the field of substance use disorders in Arab countries using bibliometric indicators. Methodology Original or review research articles authored or co-authored by investigators from Arab countries about substance use disorders during the period 1900 – 2013 were retrieved using the ISI Web of Science database. Research activity was assessed by analyzing the annual research productivity, contribution of each Arab country, names of journals, citations, and types of abused substances. Results Four hundred and thirteen documents in substance use disorders were retrieved. Annual research productivity was low but showed a significant increase in the last few years. In terms of quantity, Kingdom of Saudi Arabia (83 documents) ranked first in research about substance use disorders while Lebanon (17.4 documents per million) ranked first in terms of number of documents published per million inhabitants. Retrieved documents were found in different journal titles and categories, mostly in Drug and Alcohol Dependence Journal. Authors from USA appeared in 117 documents published by investigators from Arab countries. Citation analysis of retrieved documents showed that the average citation per document was 10.76 and the h - index was 35. The majority of retrieved documents were about tobacco and smoking (175 documents) field while alcohol consumption and abuse research was the least with 69 documents. Conclusion The results obtained suggest that research in this field was largely neglected in the past. However, recent research interest was observed. Research output on tobacco and smoking was relatively high compared to other substances of abuse like illicit drugs

  1. Nuclear medicine and imaging research (quantitative studies in radiopharmaceutical science)

    SciTech Connect

    Cooper, M.; Beck, R.N.

    1992-06-01

    This report describes three studies aimed at using radiolabeled pharmaceuticals to explore brain function and anatomy. The first section describes the chemical preparation of (F18)fluorinated benzamides (dopamine D-2 receptor tracers), (F18)fluorinated benzazepines (dopamine D-1 receptor tracers), and tissue distribution of (F18)-fluoxetine (serotonin reuptake site tracer). The second section relates pharmacological and behavioral studies of amphetamines. The third section reports on progress made with processing of brain images from CT, MRI and PET/SPECT with regards to brain metabolism of glucose during mental tasks.

  2. Global cocaine intoxication research trends during 1975-2015: a bibliometric analysis of Web of Science publications.

    PubMed

    Zyoud, Sa'ed H; Waring, W Stephen; Al-Jabi, Samah W; Sweileh, Waleed M

    2017-02-02

    Cocaine is subject to recreational abuse as a stimulant and psychoactive agent, which poses a major worldwide health problem. The aim of the present study was to perform a bibliometric analysis of publication related to cocaine intoxication an insight of the research trends at a global level to enable recommendations for future research strategies in this field. Publications about cocaine intoxication were retrieved from the Web of Science (WoS) Core Collection database on December 28, 2016, and analysed regarding the following bibliometric indicators: research trends, document types, languages, countries/territories with their h-index, collaboration patterns, journals with their impact factors (IF), and institutions. In total, 2,902 scientific publications from 1975 to 2015 were retrieved from the WoS database. The annual number of publications related to cocaine toxicity increased slightly after 1990 and reached a peak of 148 in 1992, with an average of 103 publications per year. The USA outranked other countries/territories with 2,089 publications, of which 1,927 arose exclusively from the USA and 162 involved international collaborations. The h-index for all publications related to cocaine was 212, and the h-index for all publications related to cocaine intoxication was 99. Moreover, the USA had the highest h-index of 95, followed by Spain with h-index of 24, and Canada with h-index of 24. The main research topics were consistently reproductive toxicity, clinical management of acute cocaine exposure, laboratory methods for detection of exposure to cocaine, cocaine metabolism, and cocaine toxicity in animals. This is the first bibliometric approach to examining research related to cocaine toxicity and shows that research activity has become more global and extensive since 1990. The USA remains the leading country regarding published literature, the highest h-index, and greatest role in international collaborations.

  3. Journal Productivity Distribution: Quantitative Study of Dynamic Behavior.

    ERIC Educational Resources Information Center

    Oluic-Vukovic, Vesna

    1992-01-01

    Reports on a study that examined the behavior of the journal productivity distribution curve over time using bibliographic references for research reports in chemistry and physics by Croatian authors over a 10-year period. Data characteristics of interest are described; and results regarding one-year distributions, changes in data characteristics,…

  4. Service Learning, Phonemic Perception, and Learner Motivation: A Quantitative Study

    ERIC Educational Resources Information Center

    Medina, Almitra; Gordon, Leslie

    2014-01-01

    A nine-week empirical study of 25 adults in a second language (L2) Spanish phonetics course explored whether students' participation in service-learning language exchange sessions with native Spanish speakers outside of class influenced learners' (1) motivation for foreign language learning and (2) phonemic perception in Spanish. Divided…

  5. Service Learning, Phonemic Perception, and Learner Motivation: A Quantitative Study

    ERIC Educational Resources Information Center

    Medina, Almitra; Gordon, Leslie

    2014-01-01

    A nine-week empirical study of 25 adults in a second language (L2) Spanish phonetics course explored whether students' participation in service-learning language exchange sessions with native Spanish speakers outside of class influenced learners' (1) motivation for foreign language learning and (2) phonemic perception in Spanish. Divided…

  6. Entrepreneurial Community College Presidents: An Exploratory Qualitative and Quantitative Study

    ERIC Educational Resources Information Center

    Esters, Lorenzo L.; McPhail, Christine Johnson; Singh, Robert P.; Sygielski, John J.

    2008-01-01

    This study examined the entrepreneurial, nontraditional fundraising behaviors and activities of 23 community college presidents using interview and survey data. The institutional characteristics that facilitate entrepreneurial action and how presidents are raising these new revenues were explored. "Best practices" and implications for…

  7. Commercial Activities in Primary Schools: A Quantitative Study

    ERIC Educational Resources Information Center

    Raine, Gary

    2007-01-01

    The commercialisation of schools is a controversial issue, but very little is known about the actual situation in UK schools. The aim of this study was to investigate, with particular reference to health education and health promotion, commercial activities and their regulation in primary schools in the Yorkshire and Humber region of the UK. A…

  8. Commercial Activities in Primary Schools: A Quantitative Study

    ERIC Educational Resources Information Center

    Raine, Gary

    2007-01-01

    The commercialisation of schools is a controversial issue, but very little is known about the actual situation in UK schools. The aim of this study was to investigate, with particular reference to health education and health promotion, commercial activities and their regulation in primary schools in the Yorkshire and Humber region of the UK. A…

  9. Fullerene data mining using bibliometrics and database tomography

    PubMed

    Kostoff; Braun; Schubert; Toothman; Humenik

    2000-01-01

    Database tomography (DT) is a textual database analysis system consisting of two major components: (1) algorithms for extracting multiword phrase frequencies and phrase proximities (physical closeness of the multiword technical phrases) from any type of large textual database, to augment (2) interpretative capabilities of the expert human analyst. DT was used to derive technical intelligence from a fullerenes database derived from the Science Citation Index and the Engineering Compendex. Phrase frequency analysis by the technical domain experts provided the pervasive technical themes of the fullerenes database, and phrase proximity analysis provided the relationships among the pervasive technical themes. Bibliometric analysis of the fullerenes literature supplemented the DT results with author/journal/institution publication and citation data. Comparisons of fullerenes results with past analyses of similarly structured near-earth space, chemistry, hypersonic/supersonic flow, aircraft, and ship hydrodynamics databases are made. One important finding is that many of the normalized bibliometric distribution functions are extremely consistent across these diverse technical domains and could reasonably be expected to apply to broader chemical topics than fullerenes that span multiple structural classes. Finally, lessons learned about integrating the technical domain experts with the data mining tools are presented.

  10. Motivation Measures in Sport: A Critical Review and Bibliometric Analysis

    PubMed Central

    Clancy, Rachel B.; Herring, Matthew P.; Campbell, Mark J.

    2017-01-01

    Motivation is widely-researched, in both sport psychology and other fields. As rigorous measurement is essential to understanding this latent construct, a critical appraisal of measurement instruments is needed. Thus, the purpose of this review was to evaluate the six most highly cited motivation measures in sport. Peer-reviewed articles published prior to August 2016 were searched to identify the six most highly cited motivation questionnaires in sport: Sport Motivation Scale (SMS), Intrinsic Motivation Inventory (IMI), Situational Motivational Scale (SIMS), Perceptions of Success Questionnaire (POSQ), Behavioural Regulation in Sport Questionnaire (BRSQ), and Task and Ego Orientation in Sport Questionnaire (TEOSQ). The questionnaires were then evaluated and discussed in four sections: Development, Reliability, Correlates, and Summary. Bibliometric data were also calculated (average weighted impact factor) and assessed (e.g., citations per year) to evaluate the impact of the use of each questionnaire. Despite some variance in their psychometric properties, conceptualization, structure, and utility, the six questionnaires are psychometrically strong instruments for quantifying motivation that are widely supported in the literature. Bibliometric analyses suggested that the IMI ranks first and the SMS ranks sixth according to the average weighted impact factors of their original publications. Consideration of each questionnaire's psychometric strengths/limitations, and conceptualization of motivation in the context of specific research questions should guide researchers in selecting the most appropriate instrument to measure motivation in sport. The average weighted impact factor of each questionnaire is a useful value to consider as well. With these points in mind, recommendations are provided. PMID:28337165

  11. Motivation Measures in Sport: A Critical Review and Bibliometric Analysis.

    PubMed

    Clancy, Rachel B; Herring, Matthew P; Campbell, Mark J

    2017-01-01

    Motivation is widely-researched, in both sport psychology and other fields. As rigorous measurement is essential to understanding this latent construct, a critical appraisal of measurement instruments is needed. Thus, the purpose of this review was to evaluate the six most highly cited motivation measures in sport. Peer-reviewed articles published prior to August 2016 were searched to identify the six most highly cited motivation questionnaires in sport: Sport Motivation Scale (SMS), Intrinsic Motivation Inventory (IMI), Situational Motivational Scale (SIMS), Perceptions of Success Questionnaire (POSQ), Behavioural Regulation in Sport Questionnaire (BRSQ), and Task and Ego Orientation in Sport Questionnaire (TEOSQ). The questionnaires were then evaluated and discussed in four sections: Development, Reliability, Correlates, and Summary. Bibliometric data were also calculated (average weighted impact factor) and assessed (e.g., citations per year) to evaluate the impact of the use of each questionnaire. Despite some variance in their psychometric properties, conceptualization, structure, and utility, the six questionnaires are psychometrically strong instruments for quantifying motivation that are widely supported in the literature. Bibliometric analyses suggested that the IMI ranks first and the SMS ranks sixth according to the average weighted impact factors of their original publications. Consideration of each questionnaire's psychometric strengths/limitations, and conceptualization of motivation in the context of specific research questions should guide researchers in selecting the most appropriate instrument to measure motivation in sport. The average weighted impact factor of each questionnaire is a useful value to consider as well. With these points in mind, recommendations are provided.

  12. Quantitative studies of Savannah River aquatic insects, 1959--1985

    SciTech Connect

    Soltis, R.; Hart, D.; Nagy, T.

    1986-10-30

    As part of a long-term study of water quality patterns, scientists from the Academy of Natural Sciences have collected aquatic insects from artificial substrates placed at several stations in Savannah River. This report presents the first detailed compilation and analysis of this substantial data base, and examines patterns of variations of insect distribution and abundance (both spatial and temporal) during the last quarter century. Data on the number of individuals of various taxa found in the insect traps were obtained from tables in the Academy's cursory reports. Computer data files created from these records were subjected to extensive statistical analyses in order to examine variation among stations, seasons and years in the abundances of major taxa and various aggregate properties of the insect assemblage. Although a total of 83 taxa were collected over the 27-year study, 10 taxa accounted for nearly 80% of the individuals collected from the traps, hence there 10 taxa were analyzed more intensively.

  13. Quantitative studies of Savannah River aquatic insects, 1959--1985

    SciTech Connect

    Soltis, R.; Hart, D.; Nagy, T.

    1986-10-30

    As part of a long-term study of water quality patterns, scientists from the Academy of Natural Sciences have collected aquatic insects from artificial substrates placed at several stations in Savannah River. This report presents the first detailed compilation and analysis of this substantial data base, and examines patterns of variations of insect distribution and abundance (both spatial and temporal) during the last quarter century. Data on the number of individuals of various taxa found in the insect traps were obtained from tables in the Academy`s cursory reports. Computer data files created from these records were subjected to extensive statistical analyses in order to examine variation among stations, seasons and years in the abundances of major taxa and various aggregate properties of the insect assemblage. Although a total of 83 taxa were collected over the 27-year study, 10 taxa accounted for nearly 80% of the individuals collected from the traps, hence there 10 taxa were analyzed more intensively.

  14. Quantitative Studies of Microembolization in Man during Surgical Trauma.

    DTIC Science & Technology

    1979-03-01

    implicated in the pathogene of complications following shock (1-5), trauma (6), and extracorporeal circulation (7-12). Pulmonary emboli- zation of these...limited to determining the mechanism of the reduction in microembolizatlon during cardiac surgery , the methods utilized may be applicable to the study...heart surgery . Membrane oxygenators have been advocated for use during cardiac operations because of the redici lhm in blood component trauma due to

  15. Twins born following fertility treatment: implications for quantitative genetic studies.

    PubMed

    Goody, Adam; Rice, Frances; Boivin, Jacky; Harold, Gordon T; Hay, Dale F; Thapar, Anita

    2005-08-01

    The rate of multiple births is substantially elevated in women who have had assisted reproduction treatment (ART; approximately 26%) compared to the general population ( approximately 1%), and these offspring are usually included in twin studies. Several studies have attempted to identify possible consequences of undergoing ART on the subsequent offspring. However, most studies have only included singleton births. We first examined whether twins born by ART differed from other twins on measures of childhood psychopathology, putative risk factors and correlates, and secondly tested for differences in the degree of twin similarity for available outcome measures. From a population-based twin sample, 101 families with dizygotic (DZ) twins conceived via ART were identified and compared with 1073 naturally conceived (NC) control DZ twin pairs. Analyses performed were (1) univariate and multivariate comparisons of between-group mean differences; and (2) comparison of twin 1-twin 2 correlations between the groups. The groups differed significantly on demographic factors (parental age, family size and social class) and pregnancy variables (smoking during pregnancy and birthweight) but did not differ on family conflict scores or in the frequency of obstetric complications. Family cohesion was higher in the ART group but this was accounted for by demographic factors. For child psychopathology there was a difference between the groups only for teacher-rated ADHD (Attention Deficit Hyperactivity Disorder). Differences were also found between groups for twin correlations. The differences found between ART and NC twins on group means and twin correlations suggest that researchers should be aware that including ART twins may influence results from twin studies.

  16. Trends in gel dosimetry: Preliminary bibliometric overview of active growth areas, research trends and hot topics from Gore’s 1984 paper onwards

    NASA Astrophysics Data System (ADS)

    Baldock, C.

    2017-05-01

    John Gore’s seminal 1984 paper on gel dosimetry spawned a vibrant research field ranging from fundamental science through to clinical applications. A preliminary bibliometric study was undertaken of the gel dosimetry family of publications inspired by, and resulting from, Gore’s original 1984 paper to determine active growth areas, research trends and hot topics from Gore’s paper up to and including 2016. Themes and trends of the gel dosimetry research field were bibliometrically explored by way of co-occurrence term maps using the titles and abstracts text corpora from the Web of Science database for all relevant papers from 1984 to 2016. Visualisation of similarities was used by way of the VOSviewer visualisation tool to generate cluster maps of gel dosimetry knowledge domains and the associated citation impact of topics within the domains. Heat maps were then generated to assist in the understanding of active growth areas, research trends, and emerging and hot topics in gel dosimetry.

  17. A quantitative study of a physics-first pilot program

    SciTech Connect

    Pasero, Spencer Lee; /Northern Illinois U.

    2008-09-01

    Hundreds of high schools around the United States have inverted the traditional core sequence of high school science courses, putting physics first, followed by chemistry, and then biology. A quarter-century of theory, opinion, and anecdote are available, but the literature lacks empirical evidence of the effects of the program. The current study was designed to investigate the effects of the program on science achievement gain, growth in attitude toward science, and growth in understanding of the nature of scientific knowledge. One hundred eighty-five honor students participated in this quasi-experiment, self-selecting into either the traditional or inverted sequence. Students took the Explore test as freshmen, and the Plan test as sophomores. Gain scores were calculated for the composite scores and for the science and mathematics subscale scores. A two-factor analysis of variance (ANOVA) on course sequence and cohort showed significantly greater composite score gains by students taking the inverted sequence. Participants were administered surveys measuring attitude toward science and understanding of the nature of scientific knowledge twice per year. A multilevel growth model, compared across program groups, did not show any significant effect of the inverted sequence on either attitude or understanding of the nature of scientific knowledge. The sole significant parameter showed a decline in student attitude independent of course sequence toward science over the first two years of high school. The results of this study support the theory that moving physics to the front of the science sequence can improve achievement. The importance of the composite gain score on tests vertically aligned with the high-stakes ACT is discussed, and several ideas for extensions of the current study are offered.

  18. Three quantitative studies of gender and identity in psychotherapy consultations.

    PubMed

    Langs, R; Rapp, P E; Pinto, A; Cramer, G; Badalamenti, A

    1992-04-01

    This paper details the application of three distinctive approaches to the analysis of line-by-line scores for themes of gender and identity in recorded psychotherapy consultations conducted by three male analysts with a female patient. The first method involved commonly used statistical comparisons of the frequency with which gender subthemes and allusions to identity appeared in each consultation session. The results of this study indicate three significantly different patterns of gender material in the communications from the patient with each of the analysts who interviewed her--and from each analyst and patient/analyst system as well. Therapist dominance in this area appeared to be quite strong. The second study involved measures of overall informational complexity for various aspects of the gender/identity sequence of communications. Here too, individual differences emerged. They not only add to the evidence for therapist dominance in these protocols, but also provide indications that sessions differ in respect to the extent to which the information they contain is ordered and repetitive or redundant, as compared to disordered, complex, and varied. The third study availed itself of stochastic methods in which the Box-Jenkins models were used to define mathematically and post hoc, the deeper structure of aspects of the vicissitudes of gender/identity expressions in the course of these consultations. The main finding was that change in speaker role in respect to these themes accelerated in response to random interventional shocks to the system that occurred at the time of measurement and inversely with shocks to the system sustained the previous second. This look into the deeper structure of these sequences revealed considerable sensitivity to recent shocks to the patient/therapist system, much underlying instability, and strong tendencies toward establishing stability or equilibrium when the system destabilized. Of note is the finding that all three

  19. A Quantitative Study of Magnetic Flux Transport on the Sun,

    DTIC Science & Technology

    1983-02-15

    the Sun . Using Kitt Peak magnetograms as input, as have determined a best-fit diffusion constant by comparing the computed and observed fields at later times. This paper presents the initial results of a project to simulate the transport of solar magnetic flux using diffusion, differential rotation, and meridional flow. The study concerns the evolution of large-scale fields on a time scale of weeks of years, and ignores the rapid changes that accompany the emergence of new magnetic regions and the day-to-day changes of the supergranular network

  20. Quantitative studies of bird movement: a methodological review

    USGS Publications Warehouse

    Nichols, J.D.; Kaiser, A.

    1999-01-01

    The past several years have seen development of a number of statistical models and methods for drawing inferences about bird movement using data from marked individuals. It can be difficult to keep up with this rapid development of new methods, so our purpose here is to categorize and review methods for drawing inferences about avian movement. We also outline recommendations about future work dealing both with methods development and actual studies directed at hypotheses about bird movement of interest from conservation, management, or ecological perspectives.

  1. Quantitative studies of bird movement: A methodological review

    USGS Publications Warehouse

    Nichols, J.D.; Kaiser, A.

    1999-01-01

    The past several years have seen the development of a number of statistical models and methods for drawing inferences about bird movement using data from marked individuals. It can be difficult to keep up with this rapid development of new methods, so our purpose here is to categorize and review methods for drawing inferences about avian movement. We also outline recommendations about future work, dealing both with methodological developments and with studies directed at hypotheses about bird movement of interest from conservation, management, or ecological perspectives.

  2. Study on global cloud computing research trend

    NASA Astrophysics Data System (ADS)

    Ma, Feicheng; Zhan, Nan

    2014-01-01

    Since "cloud computing" was put forward by Google , it quickly became the most popular concept in IT industry and widely permeated into various areas promoted by IBM, Microsoft and other IT industry giants. In this paper the methods of bibliometric analysis were used to investigate the global cloud computing research trend based on Web of Science (WoS) database and the Engineering Index (EI) Compendex database. In this study, the publication, countries, institutes, keywords of the papers was deeply studied in methods of quantitative analysis, figures and tables are used to describe the production and the development trends of cloud computing.

  3. A quantitative study of cochlear afferent axons in birds.

    PubMed

    Köppl, C; Wegscheider, A; Gleich, O; Manley, G A

    2000-01-01

    This paper is a comparative study of auditory-nerve morphology in birds. The chicken (Gallus gallus), the emu (Dromaius novaehollandiae) and the starling (Sturnus vulgaris) were chosen as unspecialised birds that have already been used in auditory research. The data are discussed in comparison to a similar earlier study on the barn owl, a bird with highly specialised hearing, in an attempt to separate general avian patterns from species specialisations. Average numbers of afferent fibres from 8775 (starling) to 12¿ omitted¿406 (chicken) were counted, excluding fibres to the lagenar macula. The number of fibres representing different frequency ranges showed broad maxima in the chicken and emu, corresponding to hearing ranges of best sensitivity and/or particular behavioural relevance. Mean axon diameters were around 2 microm in the chicken and starling, and around 3 microm in the emu. Virtually all auditory afferents were myelinated. The mean thickness of the myelin sheaths was between 0.33 microm (starling) and 0.4 microm (emu). There was a consistent pattern in the diameters of axons deriving from different regions. Axons from very basal, i.e. highest-frequency, parts of the basilar papilla were always the smallest. In the emu and the chicken, axons from the middle papillar regions were, in addition, larger than axons innervating apical regions.

  4. A Quantitative Study of Right Dislocation in Cantonese Spoken Discourse.

    PubMed

    Lai, Christy Choi-Ting; Law, Sam-Po; Kong, Anthony Pak-Hin

    2017-01-01

    Right Dislocation (RD) has been suggested to be a focus marking device carrying an affective function motivated by limited planning time in conversation. The current study investigated the effects of genre type, planning load and affective function on the use of RD in Cantonese monologues. Discourse data were extracted from a recently developed corpus of oral narratives in Cantonese Chinese containing language samples from 144 native Cantonese speakers evenly distributed in age, education levels and gender. Three genre types representing different structures, styles and degrees of topic familiarity were chosen for an RD analysis: procedural description, story-telling and recount of personal event. The results revealed that genre types and planning load influenced the rate of RD occurrence. (1) Specifically, the lowest proportion of RD occurred in procedural description, assumed to be the most structured genre; whereas the highest rate was found in personal event recount, considered to be the most stylized and less structured genre. (2) The highest proportion of RD appeared near the end of a narrative, where heavier cognitive load is demanded compared with the beginning of a narrative; moreover, RD also tended to co-occur with disfluency. (3) There was a high percentage of RD tokens in the personal event recount for expressing explicit emotions; and (4) a lower rate of occurrence of RD was found in monologues than previous studies based on conversations. The overall findings suggest that the use of RD is sensitive to genre structure and style, as well as planning load effects.

  5. Conformational stability of dimeric proteins: quantitative studies by equilibrium denaturation.

    PubMed Central

    Neet, K. E.; Timm, D. E.

    1994-01-01

    The conformational stability of dimeric globular proteins can be measured by equilibrium denaturation studies in solvents such as guanidine hydrochloride or urea. Many dimeric proteins denature with a 2-state equilibrium transition, whereas others have stable intermediates in the process. For those proteins showing a single transition of native dimer to denatured monomer, the conformational stabilities, delta Gu (H2O), range from 10 to 27 kcal/mol, which is significantly greater than the conformational stability found for monomeric proteins. The relative contribution of quaternary interactions to the overall stability of the dimer can be estimated by comparing delta Gu (H2O) from equilibrium denaturation studies to the free energy associated with simple dissociation in the absence of denaturant. In many cases the large stabilization energy of dimers is primarily due to the intersubunit interactions and thus gives a rationale for the formation of oligomers. The magnitude of the conformational stability is related to the size of the polypeptide in the subunit and depends upon the type of structure in the subunit interface. The practical use, interpretation, and utility of estimation of conformational stability of dimers by equilibrium denaturation methods are discussed. PMID:7756976

  6. Mesoporous Silica Nanoparticles under Sintering Conditions: A Quantitative Study.

    PubMed

    Silencieux, Fanny; Bouchoucha, Meryem; Mercier, Olivier; Turgeon, Stéphane; Chevallier, Pascale; Kleitz, Freddy; Fortin, Marc-André

    2015-12-01

    Thin films made of mesoporous silica nanoparticles (MSNs) are finding new applications in catalysis, optics, as well as in biomedicine. The fabrication of MSNs thin films requires a precise control over the deposition and sintering of MSNs on flat substrates. In this study, MSNs of narrow size distribution (150 nm) are synthesized, and then assembled onto flat silicon substrates, by means of a dip-coating process. Using concentrated MSN colloidal solutions (19.5 mg mL(-1) SiO2), withdrawal speed of 0.01 mm s(-1), and well-controlled atmospheric conditions (ambient temperature, ∼ 70% of relative humidity), monolayers are assembled under well-structured compact patterns. The thin films are sintered up to 900 °C, and the evolution of the MSNs size distributions are compared to those of their pore volumes and densities. Particle size distributions of the sintered thin films were precisely fitted using a model specifically developed for asymmetric particle size distributions. With increasing temperature, there is first evidence of intraparticle reorganization/relaxation followed by intraparticle sintering followed by interparticle sintering. This study is the first to quantify the impact of sintering on MSNs assembled as thin films.

  7. New methods for quantitative and qualitative facial studies: an overview.

    PubMed

    Thomas, I T; Hintz, R J; Frias, J L

    1989-01-01

    The clinical study of birth defects has traditionally followed the Gestalt approach, with a trend, in recent years, toward more objective delineation. Data collection, however, has been largely restricted to measurements from X-rays and anthropometry. In other fields, new techniques are being applied that capitalize on the use of modern computer technology. One such technique is that of remote sensing, of which photogrammetry is a branch. Cartographers, surveyors and engineers, using specially designed cameras, have applied geometrical techniques to locate points on an object precisely. These techniques, in their long-range application, have become part of our industrial technology and have assumed great importance with the development of satellite-borne surveillance systems. The close-range application of similar techniques has the potential for extremely accurate clinical measurement. We are currently evaluating the application of remote sensing to facial measurement using three conventional 35 mm still cameras. The subject is photographed in front of a carefully measured grid, and digitization is then carried out on 35-mm slides specific landmarks on the cranioface are identified, along with points on the background grid and the four corners of the slide frame, and are registered as xy coordinates by a digitizer. These coordinates are then converted into precise locations in object space. The technique is capable of producing measurements to within 1/100th of an inch. We suggest that remote sensing methods such as this may well be of great value in the study of congenital malformations.

  8. [Qualitative and quantitative studies of autofluorescence in fungi].

    PubMed

    Graf, B; Göbel, U B; Adam, T

    1998-01-01

    Fluorescence microscopy is an important method in mycology. It is a common procedure used in immunology or histology and more recently in modern techniques of molecular biology like in-situ hybridization. Since several molds and yeasts show autofluorescence, an interference of this phenomenon with the detection method cannot be excluded. Therefore, we studied autofluorescence in fungi in more detail, in particular with respect to the dependence of this phenomenon from growth conditions, fixing method or mounting medium used. Here we show that moulds cultivated in a liquid medium are strongly autofluorescent which could be considerably reduced by repetitive washing. In moulds, we did not find important differences in autofluorescence levels with the three fixing methods under study. However, this finding cannot be generalized. Thus, in the yeast Candida albicans we found the autofluorescence pattern being largely dependent from the fixing method and the excitation wave length, respectively. In particular, with green excitation we could show that aceton fixation resulted in strong fluorescence of individual cells within a vast population of cells showing little or no autofluorescence. In addition, we could demonstrate that mounting media are able to strongly modify autofluorescence in fungi. Using digital image acquisition with a cooled CCD camera we were able to quantify the influence of different mounting media on fluorescence intensities of Aspergillus fumigatus.

  9. A preliminary study for quantitative assessment of upper limb proprioception.

    PubMed

    Contu, Sara; Hussain, Asif; Masia, Lorenzo; Campolo, Domenico

    2016-08-01

    Proprioception, or sense of position and movement of the body, strongly correlates with motor recovery of the hemiplegic arm. The evaluation of the awareness of the location of joints in space involves measuring the accuracy of joint-angle replication. Robotic devices allow an accurate manipulation of joint movements necessary to assess proprioceptive status. This study evaluated the proprioceptive performance of healthy subjects by mean of the H-Man, a planar robot designed for upper-limb rehabilitation to gather preliminary normative data for neurorehabilitation applications. Twelve participants were equally divided into Aged and Young groups and were asked to indicate when their dominant hand position matched a predefined target in the contralateral, sagittal and ipsilateral direction. Results indicated a better performance for movements towards the contralateral target in terms of both absolute and signed error while there was not a significant effect of age group. Error variability was not affected by the target location and participants' age. The present study established preliminary proprioceptive metrics that could assist in providing information about the normal range of proprioceptive acuity of healthy subjects of different age.

  10. Endovascular Treatment for Extracranial Carotid Stenosis: A 10-Year Bibliometric Analysis.

    PubMed

    Yun, Eun-Joo; Yoon, Dae-Young; Kim, Bit-na; Min, Kyung-Joon; Kim, Bo-Yeon; Ku, You-Jin

    2015-01-01

    Bibliometric analysis is a quantitative method that can evaluate publications related to a specific topic. A PubMed database search was conducted from 2003 to 2012 using the search term "carotid" AND "stenos*" as a part of the title or abstract. A total of 1590 articles were published in 329 different journals. A total of 751 (47.2%) publications were original articles, 1501 (94.4%) were written in English, 153 (9.6%) received funding, 584 (36.7%) were published by the United States, and 673 (42.3%) resulted from multidisciplinary collaboration. Of the original articles, 538 (71.6%) had retrospective design and 275 (36.6%) had sample size of <50. Vascular surgery departments produced the most articles (n = 339, 21.3%), followed by radiology (n = 270, 17.0%), cardiology (n = 260, 16.4%), neurosurgery (n = 198, 12.5%), and neurology (n = 196, 12.3%). Five major departments published only a small portion (5.1%-26.5%) of articles in their own specialty journals. The publication in journals across disciplines and multidisciplinary collaboration are 2 peculiar characteristics of research in this topic. © The Author(s) 2015.

  11. Rutile geochemistry and its potential use in quantitative provenance studies

    NASA Astrophysics Data System (ADS)

    Zack, T.; von Eynatten, H.; Kronz, A.

    2004-10-01

    Rutile is among the most stable detrital minerals in sedimentary systems. Information contained in rutile is therefore of prime importance, especially in the study of mature sediments, where most diagnostic minerals are no longer stable. In contrast to zircon, rutile provides information about the last metamorphic cycle as rutile is not stable at greenschist facies conditions. Several known geochemical characteristics of rutile can be used to retrace provenance. The lithology of source rocks can be determined using Nb and Cr contents in rutile, because the most important source rocks for rutile, metapelites and metabasites, imprint a distinct Nb and Cr signature in rutiles. Since Zr in rutile, coexisting with zircon and quartz, is extremely temperature dependent, this relationship can be used as a geothermometer. Metapelites always contain zircon and quartz, thus the Nb and Cr signatures of metapelites indicate rutiles that can be used for thermometry. The result is effectively a single-mineral geothermometer, which is to our knowledge the first of its kind in provenance studies. Several other trace elements are variably enriched in rutile, but the processes creating these variations are so far not understood. In a case study, Al, Si, V, Cr, Fe, Zr, Nb and W contents in rutiles were obtained by electron microprobe from three sediment samples from Upstate New York. A Pleistocene glacial sand, whose source was granulite-facies rocks of the southern Adirondacks, has detrital rutile geochemical signatures which are consistent with the local Geology; a predominantly metapelitic source with a minor metabasitic contribution. Calculated temperatures for the metapelitic rutiles from the glacial sand are consistent with a predominantly granulite-facies source. The two other samples are from Paleozoic clastic wedges deposited in the foreland of the Taconian and Acadian orogenies. Here several geochemical patterns of detrital rutiles are comparable to rutiles derived from the

  12. A Quantitative Study of Simulated Bicuspid Aortic Valves

    NASA Astrophysics Data System (ADS)

    Szeto, Kai; Nguyen, Tran; Rodriguez, Javier; Pastuszko, Peter; Nigam, Vishal; Lasheras, Juan

    2010-11-01

    Previous studies have shown that congentially bicuspid aortic valves develop degenerative diseases earlier than the standard trileaflet, but the causes are not well understood. It has been hypothesized that the asymmetrical flow patterns and turbulence found in the bileaflet valves together with abnormally high levels of strain may result in an early thickening and eventually calcification and stenosis. Central to this hypothesis is the need for a precise quantification of the differences in the strain rate levels between bileaflets and trileaflet valves. We present here some in-vitro dynamic measurements of the spatial variation of the strain rate in pig aortic vales conducted in a left ventricular heart flow simulator device. We measure the strain rate of each leaflet during the whole cardiac cycle using phase-locked stereoscopic three-dimensional image surface reconstruction techniques. The bicuspid case is simulated by surgically stitching two of the leaflets in a normal valve.

  13. Quantitative study of kinetic ballooning mode theory in simple geometry

    NASA Astrophysics Data System (ADS)

    Aleynikova, Ksenia; Zocco, Alessandro

    2017-09-01

    The theory of kinetic ballooning modes (KBMs) in a magnetically confined toroidal plasma is studied analytically and numerically by means of gyrokinetic simulations. A physics-based ordering for β (the ratio of kinetic to magnetic plasma pressure) with small asymptotic parameters is found. This allows us to derive several simplified limits of previously known theories. We introduce a variational approach which provides explicit dispersion relations in terms of integrals of quadratic forms constructed from numerical eigenfunctions. It is found that, for large pressure gradients, the growth rate and frequencies computed by gyrokinetic codes show excellent agreement with those evaluated by using a diamagnetic modification of ideal magnetohydrodynamic if geometric drifts are kept consistent with the equilibrium pressure gradient. For moderate pressure gradients, a new finite-β formulation of the KBM theory is proposed. Also in this case, a good agreement between numerical simulations and analytical theory is found.

  14. Quantitative study of natural antioxidant systems for cellular nitrofurantoin toxicity.

    PubMed

    Michiels, C; Remacle, J

    1988-12-15

    The toxicity of nitrofurantoin was studied on human WI-38 fibroblasts: this chemical was lethal when added at concentrations higher than 5.10(-5) M in the culture medium. The protection afforded by antioxidants was then tested: alpha-tocopherol gave at 10(-4) M a light protection in contrast to ascorbic acid which even became toxic at high concentrations. We also tested catalase, superoxide dismutase and glutathione peroxidase introduced intracellularly by the microinjection technique. On a molecular basis, glutathione peroxidase was 23-times more efficient than catalase and 3000-times more than superoxide dismutase. The results also showed that a similar range of enzyme concentrations was found for the protection against high oxygen pressure. This suggests that, in the case of both oxygen and nitrofurantoin toxicity, the peroxide derivatives are the most toxic intermediates of the free radical attacks.

  15. Quantitative morphometric study of the subaxial cervical vertebrae end plate.

    PubMed

    Feng, Hang; Fang, Xiangyi; Huang, Dageng; Yu, Chengcheng; Zhao, Songchuan; Hao, Dingjun

    2017-02-01

    Cervical disc arthroplasty has been gradually adopted as an alternative for the treatment of cervical degenerative disease. However, there is a large discrepancy between footprints of currently available cervical disc prostheses and anatomic dimensions of cervical end plates. This study aimed to accurately and comprehensively quantify the three-dimensional (3D) anatomic morphology of the cervical vertebral end plate and provide a theoretical basis for designing appropriate disc prostheses. Moreover, we introduced a novel geometric and mechanical model for 3D reconstruction techniques of the cervical end plate. A descriptive study of the geometry of the middle and lower cervical vertebral end plates in cadaveric spines was carried out. A total of 138 cervical vertebral end plates were digitized using an optical 3D range scanning system, and then each end plate was reconstructed using the digitized image. For each end plate, the morphologic characteristics of six surface curves and the end plate concavity depth were symmetrically chosen and depicted. The cranial end plates (relative to the disc) were concave and the caudal end plates were relatively flat at all disc levels, with mean concavity depths of 2.04 and 0.69 mm, respectively. For the caudal end plates, the end plate concavity apex was most often (81.42%) located in the posterior portion, whereas in the cranial end plates, the distribution was relatively even. For the sagittal curves, the foremost point and the rearmost point on the middle curve had a more forward position than those in the left curve and the right curve. Regarding the frontal plane curves, the length of the middle curve was longer than that of the anterior curve and posterior curve. For the cranial end plate, the maximal mean depth was the middle curve, whereas for the caudal end plate, the maximum depth was the posterior curve. There is marked morphologic asymmetry, in that the cranial end plate is more concave than the corresponding

  16. Deep tendon reflexes: a study of quantitative methods.

    PubMed

    Marshall, Garrett L; Little, James W

    2002-01-01

    The deep tendon reflex (DTR) is routinely used by clinicians to evaluate the nervous system. Depressed and hyperactive DTRs suggest peripheral and central nervous system compromise, respectively. Limitations of DTRs are: qualitative nature of the assessments based upon subjective grading, and limited inter-rater reliability. This preliminary study was undertaken to quantify the tendon tap used by clinicians to elicit DTRs and the reflex response elicited. Tendon taps were applied to a force transducer in hypo-, normo-, and hyperreflexic ranges by 2 clinicians, using 3 different tendon hammers (Babinski, Queen Square, and Taylor). Patellar DTRs, measured as joint angle excursion with an electrogoniometer, were compared in hyper- and normoreflexic individuals. Median peak tap force was 1 2.8, 38.0, and 85.2 Newtons (Nt), respectively, for eliciting hyper-, normo-, and hyporeflexic DTRs. Peak tap force was similar in the hyper- and normoreflexic ranges for all 3 hammers; in the hyporeflexic range, peak tap forces with the Taylor hammer were lower. A good distinguishing feature between hyper- and normoreflexic patellar DTRs was briskness, measured as the quotient of knee excursion divided by peak tendon tap force. Knee excursion is a non-linear patellar DTR response, when measured sitting. Peak tap forces used by clinicians fall into 3 ranges: 0-20 Nt for hyperreflexia, 21-50 Nt for normoreflexia, and >50 Nt for hyporeflexia. The Taylor hammer, with small mass and short handle, has a ceiling effect in the hyporeflexic range. We propose a systematic method for DTR testing.

  17. Quantitative study of the enhancement of bulk nonlinearities in metamaterials

    SciTech Connect

    Rose, Alec; Larouche, Stephane; Smith, David R.

    2011-11-15

    Artificially structured metamaterials offer a means to enhance the weak optical nonlinearities of natural materials. The enhancement results from the inhomogeneous nature of the metamaterial unit cell, over which the local field distribution can likewise be strongly inhomogeneous, with highly localized and concentrated field regions. We investigate the nonlinear enhancement effect in metamaterials through a numerical study of four nonlinear metamaterial designs comprising arrays of metallic structures embedded in nonlinear dielectrics and operating around 10 THz. Through full-wave simulations and by employing an extended version of the transfer-matrix-based nonlinear parameter retrieval method, we confirm and quantify the enhanced nonlinearities, showing bulk quadratic nonlinear properties that are up to two orders of magnitude larger, and cubic nonlinear properties that are up to four orders of magnitude larger than the bulk nonlinear dielectric alone. Furthermore, the proposed nonlinear metamaterials support a variety of configurable nonlinear properties and regimes, including electric, magnetic, broadband, and low loss, depending on the particular geometry chosen. Finally, we use the retrieved parameters in a coupled-mode theory to predict the optimal crystal lengths and conversion efficiencies of these structures, displaying the possibility of efficient and subwavelength nonlinear devices based on metamaterials.

  18. A quantitative study of Australian aboriginal and Caucasian brains.

    PubMed Central

    Klekamp, J; Riedel, A; Harper, C; Kretschmann, H J

    1987-01-01

    The brain volumes of 8 male Australian Aborigines and 11 male Caucasians were determined. Total brain volume was significantly smaller for Aborigines (1199 +/- 84 ml) compared to Caucasians (1386 +/- 98 ml). Significantly smaller volumes were also found for cerebellum, prosencephalon-mesencephalon unit, cerebral cortex, frontal cortex, parieto-occipitotemporal cortex, and hippocampus. Volumes of ponsmedulla oblongata unit (21 +/- 3 ml for Aborigines and 22 +/- 3 ml for Caucasians) and visual cortex (14.9 ml +/- 2.6 ml and 14.6 +/- 2.2 ml, respectively) did not differ significantly. The striate cortex extended further onto the lateral surface of the occipital lobe in Aboriginal brains. The frontal portion of cerebral cortex was larger in Aboriginal than in Caucasian brains. According to the specific growth periods for the areas studied, these differences could be explained by the higher incidence of malnutrition and infectious diseases for Aboriginals during the development of the brain in early childhood, especially after the 6th postnatal month. However, genetic influences cannot be excluded. The results for the visual cortex of Aborigines might represent an adaptation to living conditions in the bush and desert regions of Australia. Images Fig. 1 PMID:3654333

  19. Quantitative study of salivary secretion in Parkinson's disease.

    PubMed

    Tumilasci, Omar R; Cersósimo, M G; Belforte, Juan E; Micheli, Federico E; Benarroch, Eduardo E; Pazo, Jorge H

    2006-05-01

    We examined basal and reflex salivary flow rate and composition in 46 patients with Parkinson's disease (PD), both in off and on conditions, compared to 13 age-matched controls without underlying disease or treatment affecting autonomic function. Whole saliva was collected 12 hours after withdrawal of dopaminergic drugs and at the peak of levodopa-induced motor improvement. Twenty-three of the 46 PD patients had received domperidone a week before the study. Basal salivary flow rate was significantly lower in PD patients in the off state compared to controls (P<0.005). Levodopa increased salivary flow rate (P<0.05) both in the domperidone-pretreated and untreated groups. Citric acid stimulated salivary flow rate in both the off and on states in PD patients. This effect was higher in the domperidone-pretreated patients. Salivary concentration of sodium, chloride, and amylase was higher in PD patients than in controls and was not affected by levodopa or domperidone treatment. Levodopa stimulates both basal and reflex salivary flow rate in PD. The mechanism appears to be central, as the effect is not blocked by domperidone. Domperidone may have a peripheral effect that potentiates reflex salivary secretion. Salivary composition is abnormal in PD and is not affected by levodopa treatment.

  20. A quantitative study of Michigan's criminal HIV exposure law.

    PubMed

    Galletly, Carol L; Pinkerton, Steven D; DiFranceisco, Wayne

    2012-01-01

    The objectives of the project were (1) to determine the extent to which HIV-positive persons living in Michigan were aware of and understood Michigan's criminal HIV exposure law, (2) to examine whether awareness of the law was associated with seropositive status disclosure to prospective sex partners, and, (3) to examine whether awareness of the law was associated with potential negative effects of the law on persons living with HIV (PLWH) including heightened HIV-related stigma, perceived societal hostility toward PLWH, and perceived need to conceal one's HIV infection. The study design was cross-sectional. A statewide sample of 384 PLWH in Michigan completed anonymous pen and paper surveys in 1 of 25 data collection sessions. A majority of participants were aware of Michigan's HIV exposure law. Awareness of the law was not associated with increased seropositive status disclosure to all prospective sex partners, decreased HIV transmission risk behavior, or increased perceived responsibility for HIV transmission prevention. However, awareness of the law was significantly associated with disclosure to a greater proportion of sex partners prior to respondents' first sexual interaction with that partner. Awareness of the law was not associated with increased HIV-related stigma, perceived societal hostility toward PLWH, or decreased comfort with seropositive status disclosure. Evidence of an effect of Michigan's HIV exposure law on seropositive status disclosure was mixed. Further research is needed to examine the various forms of HIV exposure laws among diverse groups of persons living with or at increased risk of acquiring HIV.

  1. Quantitative study on the chemical solution deposition of zinc oxysulfide

    SciTech Connect

    Reinisch, Michael; Perkins, Craig L.; Steirer, K. Xerxes

    2015-11-21

    Zinc Oxysulfide (ZnOS) has demonstrated potential in the last decade to replace CdS as a buffer layer material since it is a wide-band-gap semiconductor with performance advantages over CdS (Eg = 2.4 eV) in the near UV-range for solar energy conversion. However, questions remain on the growth mechanisms of chemical bath deposited ZnOS. In this study, a detailed model is employed to calculate solubility diagrams that describe simple conditions for complex speciation control using only ammonium hydroxide without additional base. For these conditions, ZnOS is deposited via aqueous solution deposition on a quartz crystal microbalance in a continuous flow cell. Data is used to analyze the growth rate dependence on temperature and also to elucidate the effects of dimethylsulfoxide (DMSO) when used as a co-solvent. Activation energies (EA) of ZnOS are calculated for different flow rates and solution compositions. As a result, the measured EA relationships are affected by changes in the primary growth mechanism when DMSO is included.

  2. A Quantitative Study of Michigan's Criminal HIV Exposure Law

    PubMed Central

    Galletly, Carol L.; Pinkerton, Steven D.; DiFranceisco, Wayne

    2011-01-01

    The objectives of the project were 1) to determine the extent to which HIV-positive persons living in Michigan were aware of and understood Michigan's criminal HIV exposure law, 2) to examine whether awareness of the law was associated with seropositive status disclosure to prospective sex partners, and, 3) to examine whether awareness of the law was associated with potential negative effects of the law on persons living with HIV (PLWH) including heightened HIV-related stigma, perceived societal hostility toward PLWH, and perceived need to conceal one's HIV infection. The study design was cross-sectional. A statewide sample of 384 PLWH in Michigan completed anonymous pen and paper surveys in 1 of 25 data collection sessions. A majority of participants were aware of Michigan's HIV exposure law. Awareness of the law was not associated with increased seropositive status disclosure to all prospective sex partners, decreased HIV transmission risk behavior, or increased perceived responsibility for HIV transmission prevention. However, awareness of the law was significantly associated with disclosure to a greater proportion of sex partners prior to respondents’ first sexual interaction with that partner. Awareness of the law was not associated with increased HIV-related stigma, perceived societal hostility toward PLWH, or decreased comfort with seropositive status disclosure. Evidence of an effect of Michigan's HIV exposure law on seropositive status disclosure was mixed. Further research is needed to examine the various forms of HIV exposure laws among diverse groups of persons living with or at increased risk of acquiring HIV. PMID:21861631

  3. Quantitative study on the chemical solution deposition of zinc oxysulfide

    DOE PAGES

    Reinisch, Michael; Perkins, Craig L.; Steirer, K. Xerxes

    2015-11-21

    Zinc Oxysulfide (ZnOS) has demonstrated potential in the last decade to replace CdS as a buffer layer material since it is a wide-band-gap semiconductor with performance advantages over CdS (Eg = 2.4 eV) in the near UV-range for solar energy conversion. However, questions remain on the growth mechanisms of chemical bath deposited ZnOS. In this study, a detailed model is employed to calculate solubility diagrams that describe simple conditions for complex speciation control using only ammonium hydroxide without additional base. For these conditions, ZnOS is deposited via aqueous solution deposition on a quartz crystal microbalance in a continuous flow cell.more » Data is used to analyze the growth rate dependence on temperature and also to elucidate the effects of dimethylsulfoxide (DMSO) when used as a co-solvent. Activation energies (EA) of ZnOS are calculated for different flow rates and solution compositions. As a result, the measured EA relationships are affected by changes in the primary growth mechanism when DMSO is included.« less

  4. Pain perception following different neurosurgical procedures: a quantitative prospective study.

    PubMed

    Dhandapani, Manju; Dhandapani, Sivashanmugam; Agarwal, Meena; Mahapatra, A K

    2016-08-01

    Pain following neurosurgery has never been given due attention. This was a prospective study to assess pain following various neurosurgical procedures. Patients underwent pain assessment on 11-point scale(0-10) for 24 hours following neurosurgery, and analyzed in relation to various factors. Among total 159 patients, 88(55%), 58(37%) and 13(8%) had undergone cranial, spinal and peripheral nerve procedures respectively. The mean pain score within 12 hours was 3.51(SD ± 2.53), which increased significantly during 13-24 hours to 5.06(SD ± 2.6)(P<0.001). During 13-24 hours, the pain score among those who underwent infratentorial procedures (8.02 ± 2.77) was significantly higher than among those who underwent supratentorial procedures (3.48 ± 1.99)(P<0.001). The pain score of patients who underwent lumbar surgery (6.5 ± 1.93) was significantly higher than of those who underwent cervical surgery (4.04 ± 2.43)(P<0.001). Age and gender did not show any significant influence on pain. Pain is significantly greater during 13-24 hours after neurosurgery, especially after infratentorial and lumbar surgical procedures, compared to others.

  5. Perinatal hemochromatosis. Clinical, morphologic, and quantitative iron studies.

    PubMed Central

    Silver, M. M.; Beverley, D. W.; Valberg, L. S.; Cutz, E.; Phillips, M. J.; Shaheed, W. A.

    1987-01-01

    Three sibling and two isolated-case perinates (4 newborn, 1 stillborn) died with siderotic cirrhosis and widespread parenchymal siderosis, the latter similar to that seen in both hereditary and secondary hemochromatosis. Reticuloendothelial siderosis was absent, as occurs in primary hemochromatosis. Studies of iron metabolism were performed antemortem in two of the siblings and ante-, post- and internatally in their mother, who showed hyperferremia antenatally. The only finding in the affected family suggestive of hereditary hemochromatosis was the commonly associated HLA haplotype (A3, B7) in the mother and an infant. Liver morphology, including immunocytochemistry and ultrastructure, was similar in the 5 infants and suggested that liver disease commenced as massive necrosis in midfetal life. Histologic grading and chemical assays for iron and copper on liver and spleen of the 5 index cases were compared with 26 controls; placentas were compared with 12 control placentas. Hepatic iron concentration, but not hepatic copper concentration, was significantly increased in index cases, compared with controls. Hepatic iron to copper ratio was significantly increased in index cases, compared with controls, but this ratio was unaltered in spleen and placenta. Total hepatic iron, but not total hepatic copper, was significantly increased in index cases, compared with a subgroup of 11 controls of low gestational age, similar to the fetal stage when liver disease commenced in utero. The results suggest that, irrespective of the fetal liver disease being genetic or acquired, hepatic iron overload was directly involved in pathogenesis. Images Figure 5 Figure 1 Figure 2 Figure 3 Figure 4 PMID:3307444

  6. A quantitative study of the geoeffectiveness of interplanetary structures

    NASA Astrophysics Data System (ADS)

    Vieira, L. A.

    2001-05-01

    The time-integrated values of the injection function F(E) necessary to observe variations in the Dst index during the main phase of intense magnetic storms at levels of -50, -75, -100, -125 and -150 nT, were estimated for a set of 12 interplanetary coronal mass ejections events. The dataset was classified into four groups concerning the occurrence of sheath fields just behind the shock and the polarity of the magnetic clouds: (i) magnetic clouds with polarity NS, (ii) magnetic clouds with SN polarity, (iii) magnetic clouds with southward field (Y polarity) and (iv) sheath fields. The injection function was estimated using two models of the evolution of the Dst. The time-integrated values estimated for the subset of Y clouds were found to be greater than for the other subsets. This occurs as a consequence of the slow increase of the Bs for Y clouds that leads to a smaller difference between the energy injection and the loss in the ring current that for the other groups. It is important to remember that while the energy injection is driven by the dawn-dusk component of the interplanetary electric field, the energy loss is proportional to the ring current population, with a decay time τ that varies from 3 to 20 h. The time-integrated values estimated for the subset of NS were found to be high. This is also associated to the profile of the Bs. Otherwise, sheath field and the SN magnetic cloud events seems to have shorter time-integrated values as a consequence of the sharp variation of the Bs component. In this case the energy injection is much greater than the loss energy during the main phase. These results have shown that, for the dataset studied, different structures of the interplanetary events are associated to different main phase development of the ring current. We would like to acknowledge the Fundacao de Amparo a Pesquisa do Estado de Sao Paulo for the financial support. Project numbers 98/04734-4 and 98/15959-0.

  7. Quantitative Study of Vulnerability / Damage Curves in South Africa

    NASA Astrophysics Data System (ADS)

    Pule, Tebogo

    2014-05-01

    Southern Africa is considered a stable continental region in spite of several cases of reported earthquakes, which caused considerable damage and casualties particularly in the mining industry. Most buildings and structures in South Africa are not designed to resist any intensity of earthquake and most architects, engineers and builders in the country do not consider seismic resistance as a design requirement. This is mainly because the region has not experienced any large and serious destructive earthquake in recent years. The most destructive earthquake recorded in South Africa is the Ceres earthquake of 1969. The earthquake with a magnitude of 6.3 occurred on September 29, 1969 in the Ceres-Tulbagh region of the Western Cape Province about 100 km northeast of Cape Town. Serious damage occurred to certain buildings in the area (amounting to a total of U.S. 24 million). The structural damage varied from almost total destruction of old and poorly constructed buildings to large cracks in the better-built ones, twelve people were killed and many more were injured. Another event that caused severe damage to infrastructure occurred on March 9, 2005 at Stilfontein near Klerksdorp. It is known that up to 40 or more tremors are recorded monthly in Southern Africa, the locations are predominantly in the places surrounding the gold mining areas with many events around the Carletonville and Klerksdorp areas. Recent years have seen at least four mining induced tremors causing significant damage (Welkom 1976, Klerksdorp 1977, Welkom 1989 and Carletonville 1992). Such events show that it is very necessary to take seismic events into account in the design of any infrastructure. Assessing and understanding the risk facing the South African cities as a result of major seismic activity has been paid little attention. The main focus of this study is to use results of a deterministic hazard assessment to develop the most suitable damage curves for twelve of the most common building

  8. Bibliometric mapping: eight decades of analytical chemistry, with special focus on the use of mass spectrometry.

    PubMed

    Waaijer, Cathelijn J F; Palmblad, Magnus

    2015-01-01

    In this Feature we use automatic bibliometric mapping tools to visualize the history of analytical chemistry from the 1920s until the present. In particular, we have focused on the application of mass spectrometry in different fields. The analysis shows major shifts in research focus and use of mass spectrometry. We conclude by discussing the application of bibliometric mapping and visualization tools in analytical chemists' research.

  9. Shallow science or meta-cognitive insights: a few thoughts on reflection via bibliometrics.

    PubMed

    Holden, Gary; Rosenberg, Gary; Barker, Kathleen

    2005-01-01

    The authors conclude this special issue by responding to the commentaries of their colleagues and reviewing relevant scholarship that appeared in the bibliometric literature since their literature reviews for the initial three articles in this issue were completed. They conclude, in part, that examination of bibliometric data regarding the entry of an article into the profession's knowledge base, and its ongoing life therein, may provide insights about the scientific communication process that lead to improvements of that process.

  10. Rating and Ranking the Role of Bibliometrics and Webometrics in Nursing and Midwifery

    PubMed Central

    Davidson, Patricia M.; Newton, Phillip J.; Ferguson, Caleb

    2014-01-01

    Background. Bibliometrics are an essential aspect of measuring academic and organizational performance. Aim. This review seeks to describe methods for measuring bibliometrics, identify the strengths and limitations of methodologies, outline strategies for interpretation, summarise evaluation of nursing and midwifery performance, identify implications for metric of evaluation, and specify the implications for nursing and midwifery and implications of social networking for bibliometrics and measures of individual performance. Method. A review of electronic databases CINAHL, Medline, and Scopus was undertaken using search terms such as bibliometrics, nursing, and midwifery. The reference lists of retrieved articles and Internet sources and social media platforms were also examined. Results. A number of well-established, formal ways of assessment have been identified, including h- and c-indices. Changes in publication practices and the use of the Internet have challenged traditional metrics of influence. Moreover, measuring impact beyond citation metrics is an increasing focus, with social media representing newer ways of establishing performance and impact. Conclusions. Even though a number of measures exist, no single bibliometric measure is perfect. Therefore, multiple approaches to evaluation are recommended. However, bibliometric approaches should not be the only measures upon which academic and scholarly performance are evaluated. PMID:24550691

  11. [Bibliometric indexes of the editions, publishing the articles on the problems of morphology, and some bibliometric parameters of the authors of morphological publications].

    PubMed

    Shevliuk, N N

    2013-01-01

    The article presents a comparative assessment of some bibliometric parameters of national journals, publishing the articles on the problems of morphological scientific disciplines, and concise analysis of the publication activity of morphologists. The data are given on the application of bibliometric indexes for the evaluation of the scientific contribution of national researchers to the field of morphology. The information contained in the national database-- Russian Index of Scientific Citation, and that collected by means of selected overview of the national and foreign medical and biological journals, publishing the articles on various problems of morphological sciences during the last 20 years, served as the basis for the analysis. It is noted that the authors should consider the bibliometric indexes of the journals to which they submit their articles.

  12. [Bibliometric profile of Tunisians medicals publications indexed in Medline from 2000 to 2003 party 1: productivity and cartography].

    PubMed

    Ben Abdelaziz, Ahmed; Abdelali, Mouna; Khmakhem, Abdelaziz

    2006-12-01

    The objective of this work is to quantify the Tunisian productivity in medical publications, and to determine its national cartography. It turns about a descriptive bibliometric study of the Tunisian medical researches through the whole of the papers indexed in the Medline database, and this during the period of four years, between 2 000 and 2 003. We retained only the articles which satisfied the two following conditions: on the one hand the address is a tunisian health structure and on the other hand, the first and/ or the last author is a tunisian doctor. Among the 2057 medical articles found during of the request of Medline's database, I 248 papers were eligible to the study. The indicators of the national productivity in medical publications were 27.3 articles / 100 teacher / year, de 3,2 articles / 100 W(X) habitants / year et de 10,6 articles / billion dinars / year. In addition, 97.33% of the medical tunisian publications have been produced by the hospitalo-university structures. It results of this study that the tunisian medical research is characterized by a low productivity and an important hospitalo centrism. Its development requires on the one hand more formation of doctors in research's methodology and in medical writing, and the other hand a structured activity medical documentary wakefulness and bibliometric analysis.

  13. Alternative bibliometrics from impact factor improved the esteem of a journal in a 2-year-ahead annual-citation calculation: multivariate analysis of gastroenterology and hepatology journals.

    PubMed

    Roldan-Valadez, Ernesto; Rios, Camilo

    2015-02-01

    A deeper understanding of supplementary bibliometrics beyond the impact factor might provide researchers with a better understanding of the citation process. This study presents a multivariate analysis of gastroenterology and hepatology journals to evaluate the predictive ability of seven bibliometrics in the Web of Science to calculate total cites over a 2-year period. Coincidentally, bibliometrics appearing during 2008, 2009, and 2010, with their corresponding cites in 2010, 2011, and 2012, were recorded from the Journal Citation Reports Science Edition. A linear mixed-effects design using random slopes and intercepts was performed on 51 out of 74 journals in the Gastroenterology and Hepatology category. There was a significant global effect size (R(2) = 0.992; P < 0.001), which yielded a total variance of 99.2%. The strongest predictors in the model were the Eigenfactor Score and Cited Half-life (P < 0.001), followed by the Number of Articles (P = 0.011) and the Immediacy Index (P = 0.021). The impact factor was not a significant predictor. The Eigenfactor Score and Cited Half-life predictors might be the new standards to assess the influence and importance of scientific journals; this approach may help researchers select journals in which to publish their work.

  14. Is the promotion of research reflected in bibliometric data? A network analysis of highly cited papers on the Clusters of Excellence supported under the Excellence Initiative in Germany.

    PubMed

    Bornmann, Lutz

    Under the Excellence Initiative, a number of Clusters of Excellence in Germany have been supported since 2006 and 2007-including each a limited number of cooperating institutions. The aim of the present study is to investigate whether support for Clusters of Excellence since 2006 and 2007 is reflected in bibliometric network data. For this purpose, a comparison is made between network data in the period before support started (2003-2005) and in the period after support started (2009-2011). For these two periods, a co-authorship network is generated (based on the funded institutions). This is based on publications which are among the 1 % most frequently cited publications in their respective fields and publication year and which have at least one author from Germany. As the results show, the outcomes this yields for life sciences and natural sciences differ from each other. Whereas natural sciences display an effect of establishment of Clusters of Excellence on the bibliometric networks, this was not true of life sciences. After establishment of the Clusters of Excellence, the network in natural sciences not only contained more institutions of a Cluster of Excellence, but these institutions were distributed across fewer bibliometric clusters in the network than before establishment. In other words the structure of the Clusters of Excellence was better reflected in the network.

  15. [Visualizing Research Lines in Public Health: An analysis Based on Bibliometric Maps Applied to the Revista Española de Salud Pública (2006-2015)].

    PubMed

    Gálvez, Carmen

    2016-12-01

    Identifying research lines is essential to understand the knowledge structure of a scientific domain. The aim of this study was to identify the main research topics of within the domain of public health, in the Revista Española de Saslud Pública during 2006-2015. Original articles included in the Social Sciences Citation Index (SSCI) database, available online through the Web of Science (WoS), were selected. The analysis units used were the keywords, KeyWords Plus (KW+), extracted automatically by SSCI. With KW+ obtained bibliometric, maps were created using a methodology based on the combination of co-word analysis, co-word analysis, clustering techniques and visualization techniques. We analyzed 512 documents, of which 176 KW+ were obtained with a frequency greater than or equal to 3. The results were bidimensional bibliometric maps with thematic groupings of KW+, representing the main research fronts: i) epidemiology, risk control programs disease and, in general, service organization and health policies; ii) infectious diseases, principally HIV; iii) a progressive increase in several lines interrelated with cardiovascular diseases (CVD); iv) a line multidimensional dedicated to different aspects associated to the quality of life related to health (HRQoL); and v) an emerging line linked to binge drinking. For the multidisciplinary and multidimensional nature of public health, the construction of bibliometric maps is an appropriate methodology to understand the knowledge structure of this scientific domain.

  16. Women's Selection of Quantitative Undergraduate Fields of Study: Direct and Indirect Influences.

    ERIC Educational Resources Information Center

    Ethington, Corinna A.; Wolfle, Lee M.

    1988-01-01

    Factors influencing women's decisions to pursue undergraduate degrees in quantitative fields were studied, using a structural equation model. Significant factors in High School and Beyond study data included courses taken in high school, student socioeconomic status, parental attitudes, and choice of study field as a high school sophomore. (TJH)

  17. 'Stories' or 'snapshots'? A study directed at comparing qualitative and quantitative approaches to curriculum evaluation.

    PubMed

    Pateman, B; Jinks, A M

    1999-01-01

    The focus of this paper is a study designed to explore the validity of quantitative approaches of student evaluation in a pre-registration degree programme. As managers of the students' education we were concerned that the quantitative method, which used lecturer criteria, may not fully represent students' views. The approach taken is that of a process-type strategy for curriculum evaluation as described by Parlett and Hamilton (1972). The aim of the study is to produce illuminative data, or students' 'stories' of their educational experiences through use of semi-structured interviews. The results are then compared to the current quantitative measurement tools designed to obtain 'snapshots' of the educational effectiveness of the curriculum. The quantitative measurement tools use Likert scale measurements of teacher-devised criterion statements. The results of the study give a rich source of qualitative data which can be used to inform future curriculum development. However, complete validation of the current quantitative instruments used was not achieved in this study. Student and teacher agendas in respect of important issues pertaining to the course programme were found to differ. Limitations of the study are given. There is discussion of the options open to the management team with regard to future development of curriculum evaluation systems.

  18. Bibliometric analysis and curriculum mapping of travel medicine research.

    PubMed

    Flaherty, Gerard T; Lim Yap, Keng

    2017-09-01

    Evidence-based travel medicine requires that research priorities reflect the wide knowledge base of this discipline. Bibliometric analysis of articles published in Journal of Travel Medicine yielded the following results: epidemiology (6%, n = 105); immunology/vaccinology (8.5%, n = 148); pre-travel assessment/consultation (30.5%, n = 533); diseases contracted during travel (48.3%, n = 843); other clinical conditions associated with travel (6.8%, n = 119); post-travel assessment (5.2%, n = 91) and administrative and general travel medicine issues (6%, n = 105). © International Society of Travel Medicine, 2017. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  19. Cardiovascular disease research in Latin America: A comparative bibliometric analysis

    PubMed Central

    Jahangir, Eiman; Comandé, Daniel; Rubinstein, Adolfo

    2011-01-01

    AIM: To investigate the number of publications in cardiovascular disease (CVD) in Latin America and the Caribbean over the last decade. METHODS: We performed a bibliometric analysis in PubMed from 2001 to 2010 for Latin America and the Caribbean, the United States, Canada, Europe, China, and India. RESULTS: Latin America published 4% of articles compared with 26% from the United States/Canada and 42% from Europe. In CVD, Latin America published 4% of articles vs 23% from the United States/Canada and 40% from Europe. The number of publications in CVD in Latin America increased from 41 in 2001 to 726 in 2010. CONCLUSION: Latin America, while publishing more articles than previously, lags behind developed countries. Further advances in research infrastructure are necessary to develop prevention strategies for this region. PMID:22216374

  20. Electrochemical power text mining using bibliometrics and database tomography

    NASA Astrophysics Data System (ADS)

    Kostoff, Ronald N.; Tshiteya, Rene; Pfeil, Kirstin M.; Humenik, James A.

    Database tomography (DT) is a textual database analysis system consisting of two major components: (1) algorithms for extracting multi-word phrase frequencies and phrase proximities (physical closeness of the multi-word technical phrases) from any type of large textual database, to augment (2) interpretative capabilities of the expert human analyst. DT was used to derive technical intelligence from an electrochemical power database derived from the science citation index (SCI). Phrase frequency analysis by the technical domain experts provided the pervasive technical themes of the electrochemical power database, and the phrase proximity analysis provided the relationships among the pervasive technical themes. Bibliometric analysis of the electrochemical power literature supplemented the DT results with author/journal/institution publication and citation data.