Spontaneous Focusing on Quantitative Relations: Towards a Characterization
ERIC Educational Resources Information Center
Degrande, Tine; Verschaffel, Lieven; Van Dooren, Wim
2017-01-01
In contrast to previous studies on Spontaneous Focusing on Quantitative Relations (SFOR), the present study investigated not only the "extent" to which children focus on (multiplicative) quantitative relations, but also the "nature" of children's quantitative focus (i.e., the types of quantitative relations that children focus…
Improving Middle School Students’ Quantitative Literacy through Inquiry Lab and Group Investigation
NASA Astrophysics Data System (ADS)
Aisya, N. S. M.; Supriatno, B.; Saefudin; Anggraeni, S.
2017-02-01
The purpose of this study was to analyze the application of metacognitive strategies learning based Vee Diagram through Inquiry Lab and Group Investigation toward students’ quantitative literacy. This study compared two treatments on learning activity in middle school. The metacognitive strategies have applied to the content of environmental pollution at 7th grade. This study used a quantitative approach with quasi-experimental method. The research sample were the 7th grade students, involves 27 students in the experimental through Inquiry Lab and 27 students in the experimental through Group Investigation. The instruments that used in this research were pretest and posttest quantitative literacy skills, learning step observation sheets, and the questionnaire of teachers and students responses. As the result, N-gain average of pretest and posttest increased in both experimental groups. The average of posttest score was 61,11 for the Inquiry Lab and 54,01 to the Group Investigation. The average score of N-gain quantitative literacy skill of Inquiry Lab class was 0,492 and Group Investigation class was 0,426. Both classes of experiments showed an average N-gain in the medium category. The data has been analyzed statistically by using SPSS ver.23 and the results showed that although both the learning model can develop quantitative literacy, but there is not significantly different of improving students’ quantitative literacy between Inquiry Lab and Group Investigation in environmental pollution material.
A Quantitative Comparative Study Measuring Consumer Satisfaction Based on Health Record Format
ERIC Educational Resources Information Center
Moore, Vivianne E.
2013-01-01
This research study used a quantitative comparative method to investigate the relationship between consumer satisfaction and communication based on the format of health record. The central problem investigated in this research study related to the format of health record used and consumer satisfaction with care provided and effect on communication…
Investigating Children's Abilities to Count and Make Quantitative Comparisons
ERIC Educational Resources Information Center
Lee, Joohi; Md-Yunus, Sham'ah
2016-01-01
This study was designed to investigate children's abilities to count and make quantitative comparisons. In addition, this study utilized reasoning questions (i.e., how did you know?). Thirty-four preschoolers, mean age 4.5 years old, participated in the study. According to the results, 89% of the children (n = 30) were able to do rote counting and…
Designing a mixed methods study in primary care.
Creswell, John W; Fetters, Michael D; Ivankova, Nataliya V
2004-01-01
Mixed methods or multimethod research holds potential for rigorous, methodologically sound investigations in primary care. The objective of this study was to use criteria from the literature to evaluate 5 mixed methods studies in primary care and to advance 3 models useful for designing such investigations. We first identified criteria from the social and behavioral sciences to analyze mixed methods studies in primary care research. We then used the criteria to evaluate 5 mixed methods investigations published in primary care research journals. Of the 5 studies analyzed, 3 included a rationale for mixing based on the need to develop a quantitative instrument from qualitative data or to converge information to best understand the research topic. Quantitative data collection involved structured interviews, observational checklists, and chart audits that were analyzed using descriptive and inferential statistical procedures. Qualitative data consisted of semistructured interviews and field observations that were analyzed using coding to develop themes and categories. The studies showed diverse forms of priority: equal priority, qualitative priority, and quantitative priority. Data collection involved quantitative and qualitative data gathered both concurrently and sequentially. The integration of the quantitative and qualitative data in these studies occurred between data analysis from one phase and data collection from a subsequent phase, while analyzing the data, and when reporting the results. We recommend instrument-building, triangulation, and data transformation models for mixed methods designs as useful frameworks to add rigor to investigations in primary care. We also discuss the limitations of our study and the need for future research.
ERIC Educational Resources Information Center
Haque, Mohammad Mahfujul; Little, David C.; Barman, Benoy K.; Wahab, Md. Abdul
2010-01-01
Purpose: The purpose of the study was to understand the adoption process of ricefield based fish seed production (RBFSP) that has been developed, promoted and established in Northwest Bangladesh. Design/Methodology/Approach: Quantitative investigation based on regression analysis and qualitative investigation using semi-structured interview were…
ERIC Educational Resources Information Center
Kara, Nuri
2018-01-01
The purpose of this study was to investigate university students' thoughts and practices concerning digital citizenship. An explanatory mixed methods design was used, and it involved collecting qualitative data after a quantitative phase in order to follow up on the quantitative data in more depth. In the first quantitative phase of the study, a…
Designing A Mixed Methods Study In Primary Care
Creswell, John W.; Fetters, Michael D.; Ivankova, Nataliya V.
2004-01-01
BACKGROUND Mixed methods or multimethod research holds potential for rigorous, methodologically sound investigations in primary care. The objective of this study was to use criteria from the literature to evaluate 5 mixed methods studies in primary care and to advance 3 models useful for designing such investigations. METHODS We first identified criteria from the social and behavioral sciences to analyze mixed methods studies in primary care research. We then used the criteria to evaluate 5 mixed methods investigations published in primary care research journals. RESULTS Of the 5 studies analyzed, 3 included a rationale for mixing based on the need to develop a quantitative instrument from qualitative data or to converge information to best understand the research topic. Quantitative data collection involved structured interviews, observational checklists, and chart audits that were analyzed using descriptive and inferential statistical procedures. Qualitative data consisted of semistructured interviews and field observations that were analyzed using coding to develop themes and categories. The studies showed diverse forms of priority: equal priority, qualitative priority, and quantitative priority. Data collection involved quantitative and qualitative data gathered both concurrently and sequentially. The integration of the quantitative and qualitative data in these studies occurred between data analysis from one phase and data collection from a subsequent phase, while analyzing the data, and when reporting the results. DISCUSSION We recommend instrument-building, triangulation, and data transformation models for mixed methods designs as useful frameworks to add rigor to investigations in primary care. We also discuss the limitations of our study and the need for future research. PMID:15053277
Mabikwa, Onkabetse V; Greenwood, Darren C; Baxter, Paul D; Fleming, Sarah J
2017-03-14
One aspect to consider when reporting results of observational studies in epidemiology is how quantitative risk factors are analysed. The STROBE (Strengthening the Reporting of Observational Studies in Epidemiology) guidelines recommend that researchers describe how they handle quantitative variables when analysing data. For categorised quantitative variables, the authors are required to provide reasons and justifications informing their practice. We investigated and assessed the practices and reporting of categorised quantitative variables in epidemiology. The assessment was based on five medical journals that publish epidemiological research. Observational studies published between April and June 2015 and investigating the relationships between quantitative exposures (or risk factors) and the outcomes were considered for assessment. A standard form was used to collect the data, and the reporting patterns amongst eligible studies were quantified and described. Out of 61 articles assessed for eligibility, 23 observational studies were included in the assessment. Categorisation of quantitative exposures occurred in 61% of these studies and reasons informing the practice were rarely provided. Only one article explained the choice of categorisation in the analysis. Transformation of quantitative exposures into four or five groups was common and dominant amongst studies using equally spaced categories. Dichotomisation was not popular; the practice featured in one article. Overall, the majority (86%) of the studies preferred ordered or arbitrary group categories. Other criterions used to decide categorical boundaries were based on established guidelines such as consensus statements and WHO standards. Categorisation of continuous variables remains a dominant practice in epidemiological studies. The reasons informing the practice of categorisation within published work are limited and remain unknown in most articles. The existing STROBE guidelines could provide stronger recommendations on reporting quantitative risk factors in epidemiology.
Secondary Athletic Administrators' Perceptions of Title IX Policy Changes
ERIC Educational Resources Information Center
Dahl, Gabriel Grawe
2012-01-01
The purpose of this study was to investigate North Dakota's Normal Competitive Region (NDNCR) high school athletic administrators' perceptions of 2010 Title IX policy changes respective to their athletic programs. Quantitative and qualitative data were collected to investigate the perceptions. Quantitatively, perception data were gathered from a…
Undergraduate Students' Quantitative Reasoning in Economic Contexts
ERIC Educational Resources Information Center
Mkhatshwa, Thembinkosi Peter; Doerr, Helen M.
2018-01-01
Contributing to a growing body of research on undergraduate students' quantitative reasoning, the study reported in this article used task-based interviews to investigate business calculus students' quantitative reasoning when solving two optimization tasks situated in the context of revenue and profit maximization. Analysis of verbal responses…
Spontaneous Focusing on Quantitative Relations in the Development of Children's Fraction Knowledge
ERIC Educational Resources Information Center
McMullen, Jake; Hannula-Sormunen, Minna M.; Lehtinen, Erno
2014-01-01
While preschool-aged children display some skills with quantitative relations, later learning of related fraction concepts is difficult for many students. We present two studies that investigate young children's tendency of Spontaneous Focusing On quantitative Relations (SFOR), which may help explain individual differences in the development of…
Integrating Quantitative and Qualitative Data in Mixed Methods Research--Challenges and Benefits
ERIC Educational Resources Information Center
Almalki, Sami
2016-01-01
This paper is concerned with investigating the integration of quantitative and qualitative data in mixed methods research and whether, in spite of its challenges, it can be of positive benefit to many investigative studies. The paper introduces the topic, defines the terms with which this subject deals and undertakes a literature review to outline…
Quantitative 3D investigation of Neuronal network in mouse spinal cord model
NASA Astrophysics Data System (ADS)
Bukreeva, I.; Campi, G.; Fratini, M.; Spanò, R.; Bucci, D.; Battaglia, G.; Giove, F.; Bravin, A.; Uccelli, A.; Venturi, C.; Mastrogiacomo, M.; Cedola, A.
2017-01-01
The investigation of the neuronal network in mouse spinal cord models represents the basis for the research on neurodegenerative diseases. In this framework, the quantitative analysis of the single elements in different districts is a crucial task. However, conventional 3D imaging techniques do not have enough spatial resolution and contrast to allow for a quantitative investigation of the neuronal network. Exploiting the high coherence and the high flux of synchrotron sources, X-ray Phase-Contrast multiscale-Tomography allows for the 3D investigation of the neuronal microanatomy without any aggressive sample preparation or sectioning. We investigated healthy-mouse neuronal architecture by imaging the 3D distribution of the neuronal-network with a spatial resolution of 640 nm. The high quality of the obtained images enables a quantitative study of the neuronal structure on a subject-by-subject basis. We developed and applied a spatial statistical analysis on the motor neurons to obtain quantitative information on their 3D arrangement in the healthy-mice spinal cord. Then, we compared the obtained results with a mouse model of multiple sclerosis. Our approach paves the way to the creation of a “database” for the characterization of the neuronal network main features for a comparative investigation of neurodegenerative diseases and therapies.
ERIC Educational Resources Information Center
Chen, Alvin Cheng-Hsien
2014-01-01
The present study aims to investigate how conceptual symmetry plays a role in the use of spatial particles in English and to further examine its pedagogical implications via a corpus-based evaluation of the course books in senior high schools in Taiwan. More specifically, we adopt a quantitative corpus-based approach to investigate whether bipolar…
Effects of Quantitative Linguistic Feedback to Caregivers of Young Children: A Pilot Study in China
ERIC Educational Resources Information Center
Zhang, Yiwen; Xu, Xiaojuan; Jiang, Fan; Gilkerson, Jill; Xu, Dongxin; Richards, Jeffrey A.; Harnsberger, James; Topping, Keith J.
2015-01-01
Changes in natural language environments of families receiving quantitative language feedback in Shanghai were investigated. Volunteer parents of 22 children aged 5 to 30 months were recruited from a hospital and a learning center. Quantitative measures of adult word count and conversational turns with children were collected regularly over 6…
Schmid, W; Rosland, J H; von Hofacker, S; Hunskår, I; Bruvik, F
2018-02-20
The use of music as therapy in multidisciplinary end-of-life care dates back to the 1970s and nowadays music therapy (MT) is one of the most frequently used complementary therapy in in-patient palliative care in the US. However existing research investigated music therapy's potential impact mainly from one perspective, referring to either a quantitative or qualitative paradigm. The aim of this review is to provide an overview of the users' and providers' perspectives on music therapy in palliative care within one research article. A systematic literature search was conducted using several databases supplemented with a hand-search of journals between November 1978 and December 2016. Inclusion criteria were: Music therapy with adults in palliative care conducted by a certified music therapist. Both quantitative and qualitative studies in English, German or a Scandinavian language published in peer reviewed journals were included. We aimed to identify and discuss the perspectives of both patients and health care providers on music therapy's impact in palliative care to forward a comprehensive understanding of it's effectiveness, benefits and limitations. We investigated themes mentioned by patients within qualitative studies, as well as commonly chosen outcome measures in quantitative research. A qualitative approach utilizing inductive content analysis was carried out to analyze and categorize the data. Twelve articles, reporting on nine quantitative and three qualitative research studies were included. Seven out of the nine quantitative studies investigated pain as an outcome. All of the included quantitative studies reported positive effects of the music therapy. Patients themselves associated MT with the expression of positive as well as challenging emotions and increased well-being. An overarching theme in both types of research is a psycho-physiological change through music therapy. Both quantitative as well as qualitative research showed positive changes in psycho-physiological well-being. The integration of the users´ and providers´ perspectives within future research applicable for example in mixed-methods designs is recommended.
Retention of Nontraditional Students: A Quantitative Research Study
ERIC Educational Resources Information Center
Nichols, Shirley J.
2009-01-01
The purpose of this quantitative correlational research study was to investigate, describe, and measure factors influencing retention of nontraditional first and second year students at a university located in the Midwestern United States. Retention of adult students has become a major issue for many institutions of higher education and many…
Identification of ginseng root using quantitative X-ray microtomography.
Ye, Linlin; Xue, Yanling; Wang, Yudan; Qi, Juncheng; Xiao, Tiqiao
2017-07-01
The use of X-ray phase-contrast microtomography for the investigation of Chinese medicinal materials is advantageous for its nondestructive, in situ , and three-dimensional quantitative imaging properties. The X-ray phase-contrast microtomography quantitative imaging method was used to investigate the microstructure of ginseng, and the phase-retrieval method is also employed to process the experimental data. Four different ginseng samples were collected and investigated; these were classified according to their species, production area, and sample growth pattern. The quantitative internal characteristic microstructures of ginseng were extracted successfully. The size and position distributions of the calcium oxalate cluster crystals (COCCs), important secondary metabolites that accumulate in ginseng, are revealed by the three-dimensional quantitative imaging method. The volume and amount of the COCCs in different species of the ginseng are obtained by a quantitative analysis of the three-dimensional microstructures, which shows obvious difference among the four species of ginseng. This study is the first to provide evidence of the distribution characteristics of COCCs to identify four types of ginseng, with regard to species authentication and age identification, by X-ray phase-contrast microtomography quantitative imaging. This method is also expected to reveal important relationships between COCCs and the occurrence of the effective medicinal components of ginseng.
SARGENT, DANIEL J.; GEIBEL, M.; HAWKINS, J. A.; WILKINSON, M. J.; BATTEY, N. H.; SIMPSON, D. W.
2004-01-01
• Background and Aims The aims of this investigation were to highlight the qualitative and quantitative diversity apparent between nine diploid Fragaria species and produce interspecific populations segregating for a large number of morphological characters suitable for quantitative trait loci analysis. • Methods A qualitative comparison of eight described diploid Fragaria species was performed and measurements were taken of 23 morphological traits from 19 accessions including eight described species and one previously undescribed species. A principal components analysis was performed on 14 mathematically unrelated traits from these accessions, which partitioned the species accessions into distinct morphological groups. Interspecific crosses were performed with accessions of species that displayed significant quantitative divergence and, from these, populations that should segregate for a range of quantitative traits were raised. • Key Results Significant differences between species were observed for all 23 morphological traits quantified and three distinct groups of species accessions were observed after the principal components analysis. Interspecific crosses were performed between these groups, and F2 and backcross populations were raised that should segregate for a range of morphological characters. In addition, the study highlighted a number of distinctive morphological characters in many of the species studied. • Conclusions Diploid Fragaria species are morphologically diverse, yet remain highly interfertile, making the group an ideal model for the study of the genetic basis of phenotypic differences between species through map-based investigation using quantitative trait loci. The segregating interspecific populations raised will be ideal for such investigations and could also provide insights into the nature and extent of genome evolution within this group. PMID:15469944
ERIC Educational Resources Information Center
Lang'at, Edwin K.
2014-01-01
Purpose and Method of Study: The purpose of this study was to investigate teachers' self-perceived readiness to teach school-based HIV/AIDS Awareness and Prevention education in Kenyan primary schools based on their knowledge, attitudes and instructional confidence. This research utilized a non-experimental quantitative approach with a…
ERIC Educational Resources Information Center
Collins, Kathleen M. T.; Onwuegbuzie, Anthony J.; Jiao, Qun G.
2007-01-01
A sequential design utilizing identical samples was used to classify mixed methods studies via a two-dimensional model, wherein sampling designs were grouped according to the time orientation of each study's components and the relationship of the qualitative and quantitative samples. A quantitative analysis of 121 studies representing nine fields…
Music and Suicidality: A Quantitative Review and Extension
ERIC Educational Resources Information Center
Stack, Steven; Lester, David; Rosenberg, Jonathan S.
2012-01-01
This article provides the first quantitative review of the literature on music and suicidality. Multivariate logistic regression techniques are applied to 90 findings from 21 studies. Investigations employing ecological data on suicide completions are 19.2 times more apt than other studies to report a link between music and suicide. More recent…
A Methodological Self-Study of Quantitizing: Negotiating Meaning and Revealing Multiplicity
ERIC Educational Resources Information Center
Seltzer-Kelly, Deborah; Westwood, Sean J.; Pena-Guzman, David M.
2012-01-01
This inquiry developed during the process of "quantitizing" qualitative data the authors had gathered for a mixed methods curriculum efficacy study. Rather than providing the intended rigor to their data coding process, their use of an intercoder reliability metric prompted their investigation of the multiplicity and messiness that, as they…
ERIC Educational Resources Information Center
Gkaintartzi, Anastasia; Kiliari, Angeliki; Tsokalidou, Roula
2015-01-01
This paper presents data from two studies--a nationwide quantitative research and an ethnographic study--on Greek schoolteachers' attitudes towards immigrant pupils' bilingualism. The quantitative data come from a large-scale questionnaire survey, which aimed at the investigation of the needs and requirements for the implementation of a pilot…
ERIC Educational Resources Information Center
Haralson, Mitchel, Jr.
This study investigated the influences of gender, school year, and socioeconomic status on assertiveness for black students attending four predominantly white, southeastern universities. The study employed a combination of quantitative and qualitative techniques. Quantitative data on assertiveness were collected from 560 black freshmen and juniors…
Defining Success in Adult Basic Education Settings: Multiple Stakeholders, Multiple Perspectives
ERIC Educational Resources Information Center
Tighe, Elizabeth L.; Barnes, Adrienne E.; Connor, Carol M.; Steadman, Sharilyn C.
2013-01-01
This study employed quantitative and qualitative research approaches to investigate what constitutes success in adult basic education (ABE) programs from the perspectives of multiple educational stakeholders: the state funding agency, the teachers, and the students. Success was defined in multiple ways. In the quantitative section of the study, we…
ERIC Educational Resources Information Center
Raynor, Samantha L.
2017-01-01
Investigating the validity and applicability of student success theories for minority students uncovers the nuance and context of student experiences. This study examines the validity and applicability of student engagement and involvement for Latino students. Specifically, this study employs a critical quantitative lens to question current…
Academic Advising and First-Generation College Students: A Quantitative Study on Student Retention
ERIC Educational Resources Information Center
Swecker, Hadyn K.; Fifolt, Matthew; Searby, Linda
2014-01-01
For this quantitative study, we used a multiple logistic regression technique to investigate the relationship between the number of meetings with an academic advisor and retention of first-generation students, as represented by enrollment status and academic standing at a large, public research institution in the Southeast. Consistent with…
The Sampling Issues in Quantitative Research
ERIC Educational Resources Information Center
Delice, Ali
2010-01-01
A concern for generalization dominates quantitative research. For generalizability and repeatability, identification of sample size is essential. The present study investigates 90 qualitative master's theses submitted for the Primary and Secondary School Science and Mathematics Education Departments, Mathematic Education Discipline in 10…
Reducible or irreducible? Mathematical reasoning and the ontological method.
Fisher, William P
2010-01-01
Science is often described as nothing but the practice of measurement. This perspective follows from longstanding respect for the roles mathematics and quantification have played as media through which alternative hypotheses are evaluated and experience becomes better managed. Many figures in the history of science and psychology have contributed to what has been called the "quantitative imperative," the demand that fields of study employ number and mathematics even when they do not constitute the language in which investigators think together. But what makes an area of study scientific is, of course, not the mere use of number, but communities of investigators who share common mathematical languages for exchanging quantitative and quantitative value. Such languages require rigorous theoretical underpinning, a basis in data sufficient to the task, and instruments traceable to reference standard quantitative metrics. The values shared and exchanged by such communities typically involve the application of mathematical models that specify the sufficient and invariant relationships necessary for rigorous theorizing and instrument equating. The mathematical metaphysics of science are explored with the aim of connecting principles of quantitative measurement with the structures of sufficient reason.
ERIC Educational Resources Information Center
Bohrn, Isabel C.; Altmann, Ulrike; Jacobs, Arthur M.
2012-01-01
A quantitative, coordinate-based meta-analysis combined data from 354 participants across 22 fMRI studies and one positron emission tomography (PET) study to identify the differences in neural correlates of figurative and literal language processing, and to investigate the role of the right hemisphere (RH) in figurative language processing.…
ERIC Educational Resources Information Center
Kelley, Lynn Allyson
2009-01-01
An investigation was conducted to determine whether the level of social studies interview questions second graders formulate and use can be increased with questioning instruction in terms of quality, which is defined as depth of response, and in terms of quantity. This was a quantitative study using both qualitative and quantitative data in which…
Multicenter AIDS Cohort Study Quantitative Coronary Plaque Progression Study: rationale and design.
Nakanishi, Rine; Post, Wendy S; Osawa, Kazuhiro; Jayawardena, Eranthi; Kim, Michael; Sheidaee, Nasim; Nezarat, Negin; Rahmani, Sina; Kim, Nicholas; Hathiramani, Nicolai; Susarla, Shriraj; Palella, Frank; Witt, Mallory; Blaha, Michael J; Brown, Todd T; Kingsley, Lawrence; Haberlen, Sabina A; Dailing, Christopher; Budoff, Matthew J
2018-01-01
The association of HIV with coronary atherosclerosis has been established; however, the progression of coronary atherosclerosis over time among participants with HIV is not well known. The Multicenter AIDS Cohort Study Quantitative Coronary Plaque Progression Study is a large prospective multicenter study quantifying progression of coronary plaque assessed by serial coronary computed tomography angiography (CTA). HIV-infected and uninfected men who were enrolled in the Multicenter AIDS Cohort Study Cardiovascular Substudy were eligible to complete a follow-up contrast coronary CTA 3-6 years after baseline. We measured coronary plaque volume and characteristics (calcified and noncalcified plaque including fibrous, fibrous-fatty, and low attenuation) and vulnerable plaque among HIV-infected and uninfected men using semiautomated plaque software to investigate the progression of coronary atherosclerosis over time. We describe a novel, large prospective multicenter study investigating incidence, transition of characteristics, and progression in coronary atherosclerosis quantitatively assessed by serial coronary CTAs among HIV-infected and uninfected men.
This study investigated the qualitative and quantitative neuropathological changes that occur in the fetal brain following gestational exposure to chlorpyrifos [(O,O'diethyl O-3,5,6-trichloro-2-pyridyl) phosphorothionate], a commonly used organophosphorus insecticide. Two cohort...
Applying Quantitative Genetic Methods to Primate Social Behavior
Brent, Lauren J. N.
2013-01-01
Increasingly, behavioral ecologists have applied quantitative genetic methods to investigate the evolution of behaviors in wild animal populations. The promise of quantitative genetics in unmanaged populations opens the door for simultaneous analysis of inheritance, phenotypic plasticity, and patterns of selection on behavioral phenotypes all within the same study. In this article, we describe how quantitative genetic techniques provide studies of the evolution of behavior with information that is unique and valuable. We outline technical obstacles for applying quantitative genetic techniques that are of particular relevance to studies of behavior in primates, especially those living in noncaptive populations, e.g., the need for pedigree information, non-Gaussian phenotypes, and demonstrate how many of these barriers are now surmountable. We illustrate this by applying recent quantitative genetic methods to spatial proximity data, a simple and widely collected primate social behavior, from adult rhesus macaques on Cayo Santiago. Our analysis shows that proximity measures are consistent across repeated measurements on individuals (repeatable) and that kin have similar mean measurements (heritable). Quantitative genetics may hold lessons of considerable importance for studies of primate behavior, even those without a specific genetic focus. PMID:24659839
ERIC Educational Resources Information Center
Petrites, Taralynn Wells
2017-01-01
This quantitative correlational study included an investigation of potential factors effecting high attrition rates in postsecondary online courses. Online learner-instructor interaction was examined by assessing instructor response times (RTs), student satisfaction, and final course grades at an online two-year postsecondary institution. A sample…
Examining the Inclusion of Quantitative Research in a Meta-Ethnographic Review
ERIC Educational Resources Information Center
Booker, Rhae-Ann Richardson
2010-01-01
This study explored how one might extend meta-ethnography to quantitative research for the advancement of interpretive review methods. Using the same population of 139 studies on racial-ethnic matching as data, my investigation entailed an extended meta-ethnography (EME) and comparison of its results to a published meta-analysis (PMA). Adhering to…
ERIC Educational Resources Information Center
Dogan, Soner; Yigit, Yakup
2014-01-01
The aim of this study is to investigate attitudes of school administrators and teachers working in Turkish schools towards knowledge management. In this research, an explanatory design incorporating quantitative and qualitative methods was used. The quantitative strand of the study was designed as a survey model, and the data was collected from…
Writing for Understanding: The Effect of Using Informational Writing on Student Science Achievement
ERIC Educational Resources Information Center
Parson, Atiya
2013-01-01
The purpose of this quantitative study was to investigate whether or not informational writing in the science curriculum would impact fifth grade students' science achievement and conceptual understanding. The population of this study came from a metropolitan school district in the state of Georgia for school year 2012-2013. The quantitative data…
ERIC Educational Resources Information Center
Gkaintartzi, Anastasia; Kiliari, Angeliki; Tsokalidou, Roula
2016-01-01
This paper presents data from two studies--a nationwide quantitative research and an ethnographic study--on immigrant parents' perspectives about heritage language maintenance and education in Greek state schools. The quantitative data come from a large-scale questionnaire survey, which aimed at the investigation of the needs and requirements for…
Self-Efficacy and Anxiety within an EFL Context
ERIC Educational Resources Information Center
Dogan, Cemile
2016-01-01
The current study is a quantitative research that aims to investigate the university students' self-efficacy levels and their relation to their anxiety within an EFL context. To do this, a quantitative research was conducted to scrutinize the self-efficacy and anxiety levels of students at a state university. The participants of the study were 150…
The Relationship between Stress, Coping Style, and Academic Satisfaction: A Quantitative Study
ERIC Educational Resources Information Center
Hodge-Windover, Sheila T.
2017-01-01
College students experience a great deal of stress, which is associated with poor health and poor levels of academic satisfaction which can lead to low retention. The purpose of this quantitative correlational study was to investigate how stress and coping style predict academic satisfaction and understand how and if coping style moderates the…
Chirumbolo, Antonio; Urbini, Flavio; Callea, Antonino; Lo Presti, Alessandro; Talamo, Alessandra
2017-01-01
One of the more visible effects of the societal changes is the increased feelings of uncertainty in the workforce. In fact, job insecurity represents a crucial occupational risk factor and a major job stressor that has negative consequences on both organizational well-being and individual health. Many studies have focused on the consequences about the fear and the perception of losing the job as a whole (called quantitative job insecurity), while more recently research has begun to examine more extensively the worries and the perceptions of losing valued job features (called qualitative job insecurity). The vast majority of the studies, however, have investigated the effects of quantitative and qualitative job insecurity separately. In this paper, we proposed the Job Insecurity Integrated Model aimed to examine the effects of quantitative job insecurity and qualitative job insecurity on their short-term and long-term outcomes. This model was empirically tested in two independent studies, hypothesizing that qualitative job insecurity mediated the effects of quantitative job insecurity on different outcomes, such as work engagement and organizational identification (Study 1), and job satisfaction, commitment, psychological stress and turnover intention (Study 2). Study 1 was conducted on 329 employees in private firms, while Study 2 on 278 employees in both public sector and private firms. Results robustly showed that qualitative job insecurity totally mediated the effects of quantitative on all the considered outcomes. By showing that the effects of quantitative job insecurity on its outcomes passed through qualitative job insecurity, the Job Insecurity Integrated Model contributes to clarifying previous findings in job insecurity research and puts forward a framework that could profitably produce new investigations with important theoretical and practical implications. PMID:29250013
Chirumbolo, Antonio; Urbini, Flavio; Callea, Antonino; Lo Presti, Alessandro; Talamo, Alessandra
2017-01-01
One of the more visible effects of the societal changes is the increased feelings of uncertainty in the workforce. In fact, job insecurity represents a crucial occupational risk factor and a major job stressor that has negative consequences on both organizational well-being and individual health. Many studies have focused on the consequences about the fear and the perception of losing the job as a whole (called quantitative job insecurity), while more recently research has begun to examine more extensively the worries and the perceptions of losing valued job features (called qualitative job insecurity). The vast majority of the studies, however, have investigated the effects of quantitative and qualitative job insecurity separately. In this paper, we proposed the Job Insecurity Integrated Model aimed to examine the effects of quantitative job insecurity and qualitative job insecurity on their short-term and long-term outcomes. This model was empirically tested in two independent studies, hypothesizing that qualitative job insecurity mediated the effects of quantitative job insecurity on different outcomes, such as work engagement and organizational identification (Study 1), and job satisfaction, commitment, psychological stress and turnover intention (Study 2). Study 1 was conducted on 329 employees in private firms, while Study 2 on 278 employees in both public sector and private firms. Results robustly showed that qualitative job insecurity totally mediated the effects of quantitative on all the considered outcomes. By showing that the effects of quantitative job insecurity on its outcomes passed through qualitative job insecurity, the Job Insecurity Integrated Model contributes to clarifying previous findings in job insecurity research and puts forward a framework that could profitably produce new investigations with important theoretical and practical implications.
Quantitative Research in Written Composition.
ERIC Educational Resources Information Center
Gebhard, Ann O.
Offered as an introductory guide to teachers interested in approaching written English as a "second dialect" that students must master, this review covers quantitative investigations of written language. The first section deals with developmental studies, describing how a variety of researchers have related written structure to writer maturity.…
ERIC Educational Resources Information Center
Ibrahim, Mohammed Sani; Ghavifekr, Simin; Ling, Sii; Siraj, Saedah; Azeez, Mohd Ibrahim K.
2014-01-01
This study investigates the impact of transformational leadership as idealized influence, inspirational motivation, intellectual stimulation, and individualized consideration on teachers' commitment towards organization, teaching profession, and students' learning. A quantitative survey method was applied, and four broadly hypothesized…
ERIC Educational Resources Information Center
Ferdinandi, Andrew D.; Li, Ming Hui
2007-01-01
The purpose of this quantitative study was to investigate the effect of counselor active rehabilitation service compared with the effect of standard rehabilitation counseling in assisting individuals with coexisting psychiatric and substance abuse disorders in attaining desired life roles. This study was conducted during a 6-month period in a…
Integrating Qualitative and Quantitative Research in Organizations.
1981-07-01
Qualitative Researcher Qualitative research using the traditional case study was the most popular method during the early empirical investigations of...what is now known as qualitative methods (Van Maanen, 1979). Some researchers have recently argued that restricting case studies to exploratory work... phenomenological approaches at the subjective end of the continuum. A few researchers have suggested ways in which quantitative and
ERIC Educational Resources Information Center
Liau, Albert K.; Kiat, John E.; Nie, Youyan
2015-01-01
The purpose of this study was to examine the extent to which the pedagogical approaches used in the course were related to improvements in students' attitudes toward statistics in a Quantitative Methods course for psychology undergraduate students in a Malaysian University. The study examined whether increasing availability of the instructor and…
Are Teacher Course Evaluations Biased against Faculty That Teach Quantitative Methods Courses?
ERIC Educational Resources Information Center
Royal, Kenneth D.; Stockdale, Myrah R.
2015-01-01
The present study investigated graduate students' responses to teacher/course evaluations (TCE) to determine if students' responses were inherently biased against faculty who teach quantitative methods courses. Item response theory (IRT) and Differential Item Functioning (DIF) techniques were utilized for data analysis. Results indicate students…
Relationships between Fractional Knowledge and Algebraic Reasoning: The Case of Willa
ERIC Educational Resources Information Center
Lee, Mi Yeon; Hackenberg, Amy J.
2014-01-01
To investigate relationships between students' quantitative reasoning with fractions and their algebraic reasoning, a clinical interview study was conducted with 18 middle and high school students. The students were interviewed twice, once to explore their quantitative reasoning with fractions and once to explore their solutions of problems…
ERIC Educational Resources Information Center
Mihye, Kim
2014-01-01
This study investigates Korean university English as Foreign Language (EFL) learners' task preference among three different speaking tasks. Quantitative data were collected through questionnaires and qualitative data were collected from interviews. Quantitative data were obtained from 88 survey respondents and qualitative data from 50 interview…
Examining the Teachers' Emotional Labor Behavior
ERIC Educational Resources Information Center
Tösten, Rasim; Sahin, Çigdem Çelik
2017-01-01
The aim of this research is to investigate the teachers' emotional labour behaviours and to determine the reasons of the differences. In the research, mixed research methods including both quantitative and qualitative techniques were used. The population of the study was comprised of 280 teachers (266 for quantitative, 14 for qualitative…
A Meta-Analysis of the Correlation between Heritage Language and Ethnic Identity
ERIC Educational Resources Information Center
Mu, Guanglun Michael
2015-01-01
The interaction between heritage language (HL) and ethnic identity has gained increasing scholarly attention over the past decades. Numerous quantitative studies have investigated and vindicated this interaction within certain contexts. Nevertheless, quantitative evidence on this interaction across contexts is absent to date. The current…
Methodological triangulation in a study of social support for siblings of children with cancer.
Murray, J S
1999-10-01
Triangulation is an approach to research that is becoming increasingly popular among nurse researchers. Five types of triangulation are used in nursing research: data, methodological, theoretical, researcher, and analytical triangulation. Methodological triangulation is an attempt to improve validity by combining various techniques in one study. In this article, an example of quantitative and qualitative triangulation is discussed to illustrate the procedures used and the results achieved. The secondary data used as an example are from a previous study that was conducted by the researcher and investigated nursing interventions used by pediatric oncology nurses to provide social support to siblings of children with cancer. Results show that methodological triangulation was beneficial in this study for three reasons. First, the careful comparison of quantitative and qualitative data added support for the social support variables under investigation. Second, the comparison showed more in-depth dimensions about pediatric oncology nurses providing social support to siblings of children with cancer. Finally, the use of methodological triangulation provided insight into revisions for the quantitative instrument.
ERIC Educational Resources Information Center
Epps, Sucari
2017-01-01
This quantitative study investigated the learning outcomes of students with disabilities in comparison to their non-disabled peers in a TK-12th grade school that offers a sixth-twelfth grade virtual public charter school program that currently serves students in the state of California. No differences were found between groups indicating…
Calibration methods influence quantitative material decomposition in photon-counting spectral CT
NASA Astrophysics Data System (ADS)
Curtis, Tyler E.; Roeder, Ryan K.
2017-03-01
Photon-counting detectors and nanoparticle contrast agents can potentially enable molecular imaging and material decomposition in computed tomography (CT). Material decomposition has been investigated using both simulated and acquired data sets. However, the effect of calibration methods on material decomposition has not been systematically investigated. Therefore, the objective of this study was to investigate the influence of the range and number of contrast agent concentrations within a modular calibration phantom on quantitative material decomposition. A commerciallyavailable photon-counting spectral micro-CT (MARS Bioimaging) was used to acquire images with five energy bins selected to normalize photon counts and leverage the contrast agent k-edge. Material basis matrix values were determined using multiple linear regression models and material decomposition was performed using a maximum a posteriori estimator. The accuracy of quantitative material decomposition was evaluated by the root mean squared error (RMSE), specificity, sensitivity, and area under the curve (AUC). An increased maximum concentration (range) in the calibration significantly improved RMSE, specificity and AUC. The effects of an increased number of concentrations in the calibration were not statistically significant for the conditions in this study. The overall results demonstrated that the accuracy of quantitative material decomposition in spectral CT is significantly influenced by calibration methods, which must therefore be carefully considered for the intended diagnostic imaging application.
ERIC Educational Resources Information Center
Holzhauer, Kim Elaine
2013-01-01
The purpose of the current quantitative correlational study was to investigate the relationship the qualifications of special education teachers and their preferred writing instruction method either formulaic or process writing. The study investigated the relationship between professional development in writing instruction, years of experience,…
ERIC Educational Resources Information Center
Cotreau Berube, Elyse A.
2011-01-01
The purpose of this quantitative research study was to investigate the use of rote learning in basic skills of mathematics and spelling of 12 high school students, from a career and technical high school, in an effort to learn if the pedagogy of rote fits in the frameworks of today's education. The study compared the accuracy of…
Krølner, Rikke; Rasmussen, Mette; Brug, Johannes; Klepp, Knut-Inge; Wind, Marianne; Due, Pernille
2011-10-14
Large proportions of children do not fulfil the World Health Organization recommendation of eating at least 400 grams of fruit and vegetables (FV) per day. To promote an increased FV intake among children it is important to identify factors which influence their consumption. Both qualitative and quantitative studies are needed. Earlier reviews have analysed evidence from quantitative studies. The aim of this paper is to present a systematic review of qualitative studies of determinants of children's FV intake. Relevant studies were identified by searching Anthropology Plus, Cinahl, CSA illumine, Embase, International Bibliography of the Social Sciences, Medline, PsycINFO, and Web of Science using combinations of synonyms for FV intake, children/adolescents and qualitative methods as search terms. The literature search was completed by December 1st 2010. Papers were included if they applied qualitative methods to investigate 6-18-year-olds' perceptions of factors influencing their FV consumption. Quantitative studies, review studies, studies reported in other languages than English, and non-peer reviewed or unpublished manuscripts were excluded. The papers were reviewed systematically using standardised templates for summary of papers, quality assessment, and synthesis of findings across papers. The review included 31 studies, mostly based on US populations and focus group discussions. The synthesis identified the following potential determinants for FV intake which supplement the quantitative knowledge base: Time costs; lack of taste guarantee; satiety value; appropriate time/occasions/settings for eating FV; sensory and physical aspects; variety, visibility, methods of preparation; access to unhealthy food; the symbolic value of food for image, gender identity and social interaction with peers; short term outcome expectancies. The review highlights numerous potential determinants which have not been investigated thoroughly in quantitative studies. Future large scale quantitative studies should attempt to quantify the importance of these factors. Further, mechanisms behind gender, age and socioeconomic differences in FV consumption are proposed which should be tested quantitatively in order to better tailor interventions to vulnerable groups. Finally, the review provides input to the conceptualisation and measurements of concepts (i.e. peer influence, availability in schools) which may refine survey instruments and theoretical frameworks concerning eating behaviours.
Quantitative filter forensics for indoor particle sampling.
Haaland, D; Siegel, J A
2017-03-01
Filter forensics is a promising indoor air investigation technique involving the analysis of dust which has collected on filters in central forced-air heating, ventilation, and air conditioning (HVAC) or portable systems to determine the presence of indoor particle-bound contaminants. In this study, we summarize past filter forensics research to explore what it reveals about the sampling technique and the indoor environment. There are 60 investigations in the literature that have used this sampling technique for a variety of biotic and abiotic contaminants. Many studies identified differences between contaminant concentrations in different buildings using this technique. Based on this literature review, we identified a lack of quantification as a gap in the past literature. Accordingly, we propose an approach to quantitatively link contaminants extracted from HVAC filter dust to time-averaged integrated air concentrations. This quantitative filter forensics approach has great potential to measure indoor air concentrations of a wide variety of particle-bound contaminants. Future studies directly comparing quantitative filter forensics to alternative sampling techniques are required to fully assess this approach, but analysis of past research suggests the enormous possibility of this approach. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
Mobility-Related Teacher Turnover and the Unequal Distribution of Experienced Teachers in Turkey
ERIC Educational Resources Information Center
Özoglu, Murat
2015-01-01
This study investigates the issue of mobility-related teacher turnover in Turkey through both quantitative and qualitative methods. The quantitative findings derived from descriptive and correlational analyses of countrywide teacher-assignment and transfer data indicate that a high rate of mobility-related turnover is observed in the…
ERIC Educational Resources Information Center
Gu, Qing; Sammons, Pam; Mehta, Palak
2008-01-01
This paper provides an overview of the quantitative features of research design adopted in the Department for Children, Schools and Families (DCSF; formerly DfES) funded, longitudinal mixed method study intended to investigate the impact of school leadership on pupil outcomes. It outlines the way quantitative analyses of national assessment and…
Quantitative Methods for Administrative Decision Making in Junior Colleges.
ERIC Educational Resources Information Center
Gold, Benjamin Knox
With the rapid increase in number and size of junior colleges, administrators must take advantage of the decision-making tools already used in business and industry. This study investigated how these quantitative techniques could be applied to junior college problems. A survey of 195 California junior college administrators found that the problems…
Analyses of the Impact of School Uniforms on Violence in North Carolina Public High Schools
ERIC Educational Resources Information Center
Johnson, Wesley Scott
2010-01-01
This study incorporated a multiple-methods design utilizing both quantitative and qualitative data. The quantitative portion investigated several annual reports distributed by the North Carolina Department of Public Instruction (NCDPI) to explore the impact of school uniform policies on incidents of crime and violence and occurrences of…
ERIC Educational Resources Information Center
Ozge, Aynur; Toros, Fevziye; Comelekoglu, Ulku
2004-01-01
We investigated the role of delayed cerebral maturation, hemisphere asymmetry and regional differences in children with stuttering and healthy controls during resting state and hyperventilation, using conventional EEG techniques and quantitative EEG (QEEG) analysis. This cross-sectional case control study included 26 children with stuttering and…
APA Reporting Standards in Quantitative Research Dissertations from an Online EdD Program
ERIC Educational Resources Information Center
Salgado, Griselle
2013-01-01
This study was an investigation of the reporting practices in dissertations with quantitative research designs produced by students enrolled in an online Doctor of Education (EdD) program, one that follows the American Psychological Association (APA) standards for reporting research. Limited, empirical information exists about the competencies in…
ERIC Educational Resources Information Center
Galloway, Kelli R.; Bretz, Stacey Lowery
2016-01-01
A series of quantitative studies investigated undergraduate students' perceptions of their cognitive and affective learning in the undergraduate chemistry laboratory. To explore these quantitative findings, a qualitative research protocol was developed to characterize student learning in the undergraduate chemistry laboratory. Students (N = 13)…
The Salt Creek watershed in northwest Indiana drains into Lake Michigan near several heavily used recreational beaches. This study aimed to investigate the levels of fecal indicator bacteria, enterococci and Bacteroidales, in Salt Creek using real-time quantitative PCR (qPCR) an...
Yang, Xian; Yang, Shui-Ping; Zhang, Xue; Yu, Xiao-Dong; He, Qi-Yi; Wang, Bo-Chu
2014-01-01
The aim of this paper is to develop a rapid and highly sensitive quantitative HPLC fingerprint method with multiple indicators by using the Compound Chinese Medicine Wuwei Changyanning granule and 5 herbs in the prescription. The quantitative fingerprint chromatogram with multiple indicators was investigated. і)6 compositions included rutin, gallic acid, chlorogenic acid, atractylenolide Ⅰ, pachymic acid and apigenin, which originated from 5 herbs respectively, were selected as quantitative compositions, and their contents were determined using HPLC from 11 batches granules and the corresponding 5 medicinal materials. ⅱ) The precision, stability and repeatability of fingerprinting were investigated. In addition, common peaks number, the percentage of non-common peaks and similarity were also studied. Among them, 21 common peaks in the granule could find the source of peaks from the 5 herbs, among of 10 peaks from Niuerfeng, 9 peaks from Laliao, 3 peaks from Baishu, 3 peaks from Fuling and 5 peaks from Guanghuoxiang. The results showed that the identification method of fingerprinting was reliable. PMID:25587307
ERIC Educational Resources Information Center
Frazier, Eugene
2013-01-01
This study investigated the relationship among organizational leadership styles (criterion variables), organizational culture, and employee job satisfaction, and organizational performance (predictor variables). The study research method was the quantitative method using a correlational research design that investigated the relationship among the…
Crandell, Jamie L.; Voils, Corrine I.; Chang, YunKyung; Sandelowski, Margarete
2010-01-01
The possible utility of Bayesian methods for the synthesis of qualitative and quantitative research has been repeatedly suggested but insufficiently investigated. In this project, we developed and used a Bayesian method for synthesis, with the goal of identifying factors that influence adherence to HIV medication regimens. We investigated the effect of 10 factors on adherence. Recognizing that not all factors were examined in all studies, we considered standard methods for dealing with missing data and chose a Bayesian data augmentation method. We were able to summarize, rank, and compare the effects of each of the 10 factors on medication adherence. This is a promising methodological development in the synthesis of qualitative and quantitative research. PMID:21572970
Lee, Wai-Yung; Nakamura, Shin-Ichi; Chung, Moon Ja; Chun, Young Ju; Fu, Meng; Liang, Shu-Chuan; Liu, Cui-Lian
2013-09-01
The purpose of this study was to explore variations in how contemporary couples from five different Asian regions negotiate disagreements. Video recordings of 50 couples (10 each from Japan, Korea, Mainland China, Taiwan, and Hong Kong) discussing unresolved disagreements provided raw data for quantitative and qualitative analyses. First, teams of coders from each region used a common protocol to make quantitative ratings of content themes and interaction patterns for couples from their own region. An interregional panel of investigators then performed in-depth qualitative reviews for half of these cases, noting cultural differences not only in observed patterns of couple behavior but also in their own perceptions of these patterns. Both quantitative and qualitative analyses revealed clear regional differences on dimensions such as overt negativity, demand-withdraw interaction, and collaboration. The qualitative results also provided a richer, more nuanced view of other (e.g., gender-linked) conflict management patterns that the quantitative analyses did not capture. Inconsistencies between qualitative and quantitative data and between the qualitative observations of investigators from different regions were most pronounced for couples from Korea and Japan, whose conflict styles were subtler and less direct than those of couples from the other regions. © FPI, Inc.
ERIC Educational Resources Information Center
Strickland, Crystal Y.
2013-01-01
The purpose of this quantitative study was to investigate the extent to which professional development practices in professional learning communities are consistent with research-based principles of effective professional development. Additionally, the study investigated potential differences in the content focus, active learning, coherence, and…
ERIC Educational Resources Information Center
Ozkan, Hurside Kubra; Aksoy, Ayse Belgin
2017-01-01
Purpose: The present study aims to investigate maternal emotion socialization, children's self-perception, and social problem-solving skills. In addition, this study describes the association between the levels of children's self-perception and social problem-solving skills. Research Methods: This is a quantitative study adopting a relational…
An Investigation on Students Academic Performance for Junior Secondary Schools in Botswana
ERIC Educational Resources Information Center
MolokoMphale, Luke; Mhlauli, Mavis B.
2014-01-01
The major purpose of the study was to investigate factors which contribute to the decline in students' academic performance in junior secondary schools in Botswana since 2010. The study was mainly quantitative and used the positivist inquiry paradigm. The study employed critical theory for its theoretical framework. Questionnaires were used to…
Quantitative susceptibility mapping of human brain at 3T: a multisite reproducibility study.
Lin, P-Y; Chao, T-C; Wu, M-L
2015-03-01
Quantitative susceptibility mapping of the human brain has demonstrated strong potential in examining iron deposition, which may help in investigating possible brain pathology. This study assesses the reproducibility of quantitative susceptibility mapping across different imaging sites. In this study, the susceptibility values of 5 regions of interest in the human brain were measured on 9 healthy subjects following calibration by using phantom experiments. Each of the subjects was imaged 5 times on 1 scanner with the same procedure repeated on 3 different 3T systems so that both within-site and cross-site quantitative susceptibility mapping precision levels could be assessed. Two quantitative susceptibility mapping algorithms, similar in principle, one by using iterative regularization (iterative quantitative susceptibility mapping) and the other with analytic optimal solutions (deterministic quantitative susceptibility mapping), were implemented, and their performances were compared. Results show that while deterministic quantitative susceptibility mapping had nearly 700 times faster computation speed, residual streaking artifacts seem to be more prominent compared with iterative quantitative susceptibility mapping. With quantitative susceptibility mapping, the putamen, globus pallidus, and caudate nucleus showed smaller imprecision on the order of 0.005 ppm, whereas the red nucleus and substantia nigra, closer to the skull base, had a somewhat larger imprecision of approximately 0.01 ppm. Cross-site errors were not significantly larger than within-site errors. Possible sources of estimation errors are discussed. The reproducibility of quantitative susceptibility mapping in the human brain in vivo is regionally dependent, and the precision levels achieved with quantitative susceptibility mapping should allow longitudinal and multisite studies such as aging-related changes in brain tissue magnetic susceptibility. © 2015 by American Journal of Neuroradiology.
ERIC Educational Resources Information Center
Lee, Jennifer
2012-01-01
The intent of this study was to examine the relationship between media multitasking orientation and grade point average. The study utilized a mixed-methods approach to investigate the research questions. In the quantitative section of the study, the primary method of statistical analyses was multiple regression. The independent variables for the…
ERIC Educational Resources Information Center
Soebari, Titien; Aldridge, Jill M.
2016-01-01
This article reports on the differential effectiveness of a teacher professional development programme for teachers in urban and rural schools in Indonesia. The study employed an embedded mixed methods design that involved the concurrent collection of both quantitative and qualitative data. The quantitative component involved a pre-post design in…
Quantitative and Qualitative Change in Children's Mental Rotation Performance
ERIC Educational Resources Information Center
Geiser, Christian; Lehmann, Wolfgang; Corth, Martin; Eid, Michael
2008-01-01
This study investigated quantitative and qualitative changes in mental rotation performance and solution strategies with a focus on sex differences. German children (N = 519) completed the Mental Rotations Test (MRT) in the 5th and 6th grades (interval: one year; age range at time 1: 10-11 years). Boys on average outperformed girls on both…
Experiencing Teaching and Learning Quantitative Reasoning in a Project-Based Context
ERIC Educational Resources Information Center
Muir, Tracey; Beswick, Kim; Callingham, Rosemary; Jade, Katara
2016-01-01
This paper presents the findings of a small-scale study that investigated the issues and challenges of teaching and learning about quantitative reasoning (QR) within a project-based learning (PjBL) context. Students and teachers were surveyed and interviewed about their experiences of learning and teaching QR in that context in contrast to…
ERIC Educational Resources Information Center
Habowski, Thomas; Mouza, Chrystalla
2014-01-01
This study investigates pre-service teachers' TPACK development in a secondary science teacher education program that combined a content-specific technology integration course with extensive field experience. Both quantitative and qualitative data were collected. Quantitative data were collected through a pre-post administration of the…
Students' Misconceptions about the Ozone Layer and the Effect of Internet-Based Media on It
ERIC Educational Resources Information Center
Gungordu, Nahide; Yalcin-Celik, Ayse; Kilic, Ziya
2017-01-01
In this study, students' misconceptions about the ozone layer were investigated, looking specifically at the effect internet-based media has on the formation of these misconceptions. Quantitative and qualitative research approaches were used to perform the research. As part of the quantitative portion of the research, the descriptive survey…
ERIC Educational Resources Information Center
Danelczyk, Ewa Krystyna
2013-01-01
The purpose of this quantitative causal-comparative study was to investigate the relationship between the instructional effects of the interactive whiteboard and students' proficiency levels in eighth-grade science as evidenced by the state FCAT scores. A total of 46 eighth-grade science teachers in a South Florida public school district completed…
ERIC Educational Resources Information Center
Jamison, Joseph A.
2013-01-01
This quantitative study sought to determine whether there were significant statistical differences between the performance scores of special education and general education students' scores when in team or solo-teaching environments as may occur in inclusively taught classrooms. The investigated problem occurs because despite education's stated…
Roche, Y; Cantin, D; Vigier, J; Boucherle, A
1978-03-01
Amino-2 Benzimidazole, a residue of the decomposition of some fungicides (Benomyl, Carbendazine, Thiophanate, Methylthiophanate), is measured by polarography in aqueous medium, with a platinium rotating electrode, for the exploration in potentials from +0.5 v to 1.4 v. The best conditions for the quantitative determination are investigated, the study according to pH is performed and the standard curve is given for concentrations from 10(-5) to 10(-3) M/l. The interaction of elementts found in tap water and in aquarium water is also investigated.
ERIC Educational Resources Information Center
Chiu, Yen-Yen L.
2012-01-01
The quantitative correlational research study investigated the statistical relationship between school certificated staff perceptions of the multicultural inclusivity of school policies and fifth through ninth grade students' feelings of school belonging. The study was located in a community of San Diego, California with 77 employed certificated…
Teacher Contract Non-Renewal: Southeast and Midwest Principals
ERIC Educational Resources Information Center
Nixon, Andy; Packard, Abbot L; Dam, Margaret
2011-01-01
This quantitative study investigated reasons that school principals recommend non-renewal of probationary teachers' contracts. Principals in the Southeast and Midwest completed an emailed survey. The ordinal nature of the data gathered dictated that comparisons be made between groups using the Mann Whitney U. The study investigated the barriers…
Fu, Guifang; Dai, Xiaotian; Symanzik, Jürgen; Bushman, Shaun
2017-01-01
Leaf shape traits have long been a focus of many disciplines, but the complex genetic and environmental interactive mechanisms regulating leaf shape variation have not yet been investigated in detail. The question of the respective roles of genes and environment and how they interact to modulate leaf shape is a thorny evolutionary problem, and sophisticated methodology is needed to address it. In this study, we investigated a framework-level approach that inputs shape image photographs and genetic and environmental data, and then outputs the relative importance ranks of all variables after integrating shape feature extraction, dimension reduction, and tree-based statistical models. The power of the proposed framework was confirmed by simulation and a Populus szechuanica var. tibetica data set. This new methodology resulted in the detection of novel shape characteristics, and also confirmed some previous findings. The quantitative modeling of a combination of polygenetic, plastic, epistatic, and gene-environment interactive effects, as investigated in this study, will improve the discernment of quantitative leaf shape characteristics, and the methods are ready to be applied to other leaf morphology data sets. Unlike the majority of approaches in the quantitative leaf shape literature, this framework-level approach is data-driven, without assuming any pre-known shape attributes, landmarks, or model structures. © 2016 The Authors. New Phytologist © 2016 New Phytologist Trust.
Quantitative geomorphologic studies from spaceborne platforms
NASA Technical Reports Server (NTRS)
Williams, R. S., Jr.
1985-01-01
Although LANDSAT images of our planet represent a quantum improvement in the availability of a global image-data set for independent or comparative regional geomorphic studies of landforms, such images have several limitations which restrict their suitability for quantitative geomorphic investigations. The three most serious deficiencies are: (1) photogrammetric inaccuracies, (2) two-dimensional nature of the data, and (3) spatial resolution. These deficiencies are discussed, as well as the use of stereoscopic images and laser altimeter data.
Kim, Paul; Lee, Ju Kang; Lim, Oh Kyung; Park, Heung Kyu; Park, Ki Deok
2017-12-01
To predict the probability of lymphedema development in breast cancer patients in the early post-operation stage, we investigated the ability of quantitative lymphoscintigraphic assessment. This retrospective study included 201 patients without lymphedema after unilateral breast cancer surgery. Lymphoscintigraphy was performed between 4 and 8 weeks after surgery to evaluate the lymphatic system in the early postoperative stage. Quantitative lymphoscintigraphy was performed using four methods: ratio of radiopharmaceutical clearance rate of the affected to normal hand; ratio of radioactivity of the affected to normal hand; ratio of radiopharmaceutical uptake rate of the affected to normal axilla (RUA); and ratio of radioactivity of the affected to normal axilla (RRA). During a 1-year follow-up, patients with a circumferential interlimb difference of 2 cm at any measurement location and a 200-mL interlimb volume difference were diagnosed with lymphedema. We investigated the difference in quantitative lymphoscintigraphic assessment between the non-lymphedema and lymphedema groups. Quantitative lymphoscintigraphic assessment revealed that the RUA and RRA were significantly lower in the lymphedema group than in the non-lymphedema group. After adjusting the model for all significant variables (body mass index, N-stage, T-stage, type of surgery, and type of lymph node surgery), RRA was associated with lymphedema (odds ratio=0.14; 95% confidence interval, 0.04-0.46; p=0.001). In patients in the early postoperative stage after unilateral breast cancer surgery, quantitative lymphoscintigraphic assessment can be used to predict the probability of developing lymphedema.
What Are We Doing When We Translate from Quantitative Models?
Critchfield, Thomas S; Reed, Derek D
2009-01-01
Although quantitative analysis (in which behavior principles are defined in terms of equations) has become common in basic behavior analysis, translational efforts often examine everyday events through the lens of narrative versions of laboratory-derived principles. This approach to translation, although useful, is incomplete because equations may convey concepts that are difficult to capture in words. To support this point, we provide a nontechnical introduction to selected aspects of quantitative analysis; consider some issues that translational investigators (and, potentially, practitioners) confront when attempting to translate from quantitative models; and discuss examples of relevant translational studies. We conclude that, where behavior-science translation is concerned, the quantitative features of quantitative models cannot be ignored without sacrificing conceptual precision, scientific and practical insights, and the capacity of the basic and applied wings of behavior analysis to communicate effectively. PMID:22478533
ERIC Educational Resources Information Center
Fatima, Irum; Pathan, Zahid Hussain
2016-01-01
The primary purpose of this research is to investigate the vocabulary learning strategies employed by the undergraduate students of Sardar Bahadur Khan Women's University (SBKWU) and University of Balochistan (UOB), Quetta, Pakistan. A quantitative design was employed in this study to answer the two research questions of the present study. The…
ERIC Educational Resources Information Center
Elcin, Melih; Sezer, Baris
2014-01-01
The purpose of this study was to investigate the impact of anchored instruction on the students in secondary school math studies classrooms. This study adopted a quasi-experimental design. This research involved both quantitative and qualitative methods to investigate the effects of anchored instruction on students' academical achievement,…
ERIC Educational Resources Information Center
Eskin, Handan; Ogan-Bekiroglu, Feral
2009-01-01
The aim of this study was, first, to investigate any pattern between students' quantitative contribution to argumentation and their science understanding, and second, to analyze any relationship between students' qualitative contribution to argumentation and their scientific knowledge. Participants of the study were four tenth-grade students. The…
ERIC Educational Resources Information Center
Yilmaz, Yasemin; Durmus, Soner; Yaman, Hakan
2018-01-01
This study investigated the pattern problems posed by middle school mathematics preservice teachers using multiple representations to determine both their pattern knowledge levels and their abilities to transfer this knowledge to students. The design of the study is the survey method, one of the quantitative research methods. The study group was…
Pütter, Carolin; Pechlivanis, Sonali; Nöthen, Markus M; Jöckel, Karl-Heinz; Wichmann, Heinz-Erich; Scherag, André
2011-01-01
Genome-wide association studies have identified robust associations between single nucleotide polymorphisms and complex traits. As the proportion of phenotypic variance explained is still limited for most of the traits, larger and larger meta-analyses are being conducted to detect additional associations. Here we investigate the impact of the study design and the underlying assumption about the true genetic effect in a bimodal mixture situation on the power to detect associations. We performed simulations of quantitative phenotypes analysed by standard linear regression and dichotomized case-control data sets from the extremes of the quantitative trait analysed by standard logistic regression. Using linear regression, markers with an effect in the extremes of the traits were almost undetectable, whereas analysing extremes by case-control design had superior power even for much smaller sample sizes. Two real data examples are provided to support our theoretical findings and to explore our mixture and parameter assumption. Our findings support the idea to re-analyse the available meta-analysis data sets to detect new loci in the extremes. Moreover, our investigation offers an explanation for discrepant findings when analysing quantitative traits in the general population and in the extremes. Copyright © 2011 S. Karger AG, Basel.
ERIC Educational Resources Information Center
Small, Christine J.; Newtoff, Kiersten N.
2013-01-01
Undergraduate biology education is undergoing dramatic changes, emphasizing student training in the "tools and practices" of science, particularly quantitative and problem-solving skills. We redesigned a freshman ecology lab to emphasize the importance of scientific inquiry and quantitative reasoning in biology. This multi-week investigation uses…
Exploring Phytoplankton Population Investigation Growth to Enhance Quantitative Literacy
ERIC Educational Resources Information Center
Baumgartner, Erin; Biga, Lindsay; Bledsoe, Karen; Dawson, James; Grammer, Julie; Howard, Ava; Snyder, Jeffrey
2015-01-01
Quantitative literacy is essential to biological literacy (and is one of the core concepts in "Vision and Change in Undergraduate Biology Education: A Call to Action"; AAAS 2009). Building quantitative literacy is a challenging endeavor for biology instructors. Integrating mathematical skills into biological investigations can help build…
Xie, Weilong; Yu, Kangfu; Pauls, K Peter; Navabi, Alireza
2012-04-01
The effectiveness of image analysis (IA) compared with an ordinal visual scale, for quantitative measurement of disease severity, its application in quantitative genetic studies, and its effect on the estimates of genetic parameters were investigated. Studies were performed using eight backcross-derived families of common bean (Phaseolus vulgaris) (n = 172) segregating for the molecular marker SU91, known to be associated with a quantitative trait locus (QTL) for resistance to common bacterial blight (CBB), caused by Xanthomonas campestris pv. phaseoli and X. fuscans subsp. fuscans. Even though both IA and visual assessments were highly repeatable, IA was more sensitive in detecting quantitative differences between bean genotypes. The CBB phenotypic difference between the two SU91 genotypic groups was consistently more than fivefold for IA assessments but generally only two- to threefold for visual assessments. Results suggest that the visual assessment results in overestimation of the effect of QTL in genetic studies. This may have been caused by lack of additivity and uneven intervals of the visual scale. Although visual assessment of disease severity is a useful tool for general selection in breeding programs, assessments using IA may be more suitable for phenotypic evaluations in quantitative genetic studies involving CBB resistance as well as other foliar diseases.
Investigating How the Biographies of Today's Scientists Affect 8th Graders' Scientist Image
ERIC Educational Resources Information Center
Karaçam, Sedat
2016-01-01
This study aimed to investigate how a poster study focusing on the biographies of today's scientists affected 8th graders' scientist images. The study utilized a mixed model which combined qualitative and quantitative research techniques. 142 8th graders from a secondary school in Ankara Province Keçiören District participated in the study.…
ERIC Educational Resources Information Center
Hess, Justin L.; Strobel, Johannes; Pan, Rui; Wachter Morris, Carrie A.
2017-01-01
This study focuses on two seldom-investigated skills or dispositions aligned with engineering habits of mind--empathy and care. In order to conduct quantitative research, we designed, explored the underlying structure of, validated, and tested the reliability of the Empathy and Care Questionnaire (ECQ), a new psychometric instrument. In the second…
Unique programming: an examination of the benefits of a free choice program
Dorothy L. Schmalz; Deborah L. Kerstetter; Harry C. Zinn
2002-01-01
This study was an investigation of a free choice program and the benefits free choice yields on the developing characteristics of self-esteem and intrinsic motivation among adolescent girls. Both quantitative and qualitative data were collected at Brown Ledge Camp, an all girls summer camp outside of Burlington, Vermont, during the summer of 2000. Quantitative results...
ERIC Educational Resources Information Center
Kus, Zafer
2014-01-01
This research aims to investigate democratic environments offered to children in Turkey at school, in the home, and in society. A mixed method is a general type of research where qualitative and quantitative methods are used together. The researcher first collects quantitative and then the qualitative data. The study group in the research…
2011-01-01
Background Large proportions of children do not fulfil the World Health Organization recommendation of eating at least 400 grams of fruit and vegetables (FV) per day. To promote an increased FV intake among children it is important to identify factors which influence their consumption. Both qualitative and quantitative studies are needed. Earlier reviews have analysed evidence from quantitative studies. The aim of this paper is to present a systematic review of qualitative studies of determinants of children's FV intake. Methods Relevant studies were identified by searching Anthropology Plus, Cinahl, CSA illumine, Embase, International Bibliography of the Social Sciences, Medline, PsycINFO, and Web of Science using combinations of synonyms for FV intake, children/adolescents and qualitative methods as search terms. The literature search was completed by December 1st 2010. Papers were included if they applied qualitative methods to investigate 6-18-year-olds' perceptions of factors influencing their FV consumption. Quantitative studies, review studies, studies reported in other languages than English, and non-peer reviewed or unpublished manuscripts were excluded. The papers were reviewed systematically using standardised templates for summary of papers, quality assessment, and synthesis of findings across papers. Results The review included 31 studies, mostly based on US populations and focus group discussions. The synthesis identified the following potential determinants for FV intake which supplement the quantitative knowledge base: Time costs; lack of taste guarantee; satiety value; appropriate time/occasions/settings for eating FV; sensory and physical aspects; variety, visibility, methods of preparation; access to unhealthy food; the symbolic value of food for image, gender identity and social interaction with peers; short term outcome expectancies. Conclusions The review highlights numerous potential determinants which have not been investigated thoroughly in quantitative studies. Future large scale quantitative studies should attempt to quantify the importance of these factors. Further, mechanisms behind gender, age and socioeconomic differences in FV consumption are proposed which should be tested quantitatively in order to better tailor interventions to vulnerable groups. Finally, the review provides input to the conceptualisation and measurements of concepts (i.e. peer influence, availability in schools) which may refine survey instruments and theoretical frameworks concerning eating behaviours. PMID:21999291
Quantitative MR imaging in fracture dating--Initial results.
Baron, Katharina; Neumayer, Bernhard; Widek, Thomas; Schick, Fritz; Scheicher, Sylvia; Hassler, Eva; Scheurer, Eva
2016-04-01
For exact age determinations of bone fractures in a forensic context (e.g. in cases of child abuse) improved knowledge of the time course of the healing process and use of non-invasive modern imaging technology is of high importance. To date, fracture dating is based on radiographic methods by determining the callus status and thereby relying on an expert's experience. As a novel approach, this study aims to investigate the applicability of magnetic resonance imaging (MRI) for bone fracture dating by systematically investigating time-resolved changes in quantitative MR characteristics after a fracture event. Prior to investigating fracture healing in children, adults were examined for this study in order to test the methodology for this application. Altogether, 31 MR examinations in 17 subjects (♀: 11 ♂: 6; median age 34 ± 15 y, scanned 1-5 times over a period of up to 200 days after the fracture event) were performed on a clinical 3T MR scanner (TimTrio, Siemens AG, Germany). All subjects were treated conservatively for a fracture in either a long bone or in the collar bone. Both, qualitative and quantitative MR measurements were performed in all subjects. MR sequences for a quantitative measurement of relaxation times T1 and T2 in the fracture gap and musculature were applied. Maps of quantitative MR parameters T1, T2, and magnetisation transfer ratio (MTR) were calculated and evaluated by investigating changes over time in the fractured area by defined ROIs. Additionally, muscle areas were examined as reference regions to validate this approach. Quantitative evaluation of 23 MR data sets (12 test subjects, ♀: 7 ♂: 5) showed an initial peak in T1 values in the fractured area (T1=1895 ± 607 ms), which decreased over time to a value of 1094 ± 182 ms (200 days after the fracture event). T2 values also peaked for early-stage fractures (T2=115 ± 80 ms) and decreased to 73 ± 33 ms within 21 days after the fracture event. After that time point, no significant changes could be detected for T2. MTR remained constant at 35.5 ± 8.0% over time. The study shows that the quantitative assessment of T1 and T2 behaviour over time in the fractured region enable the generation of a novel model allowing for an objective age determination of a fracture. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.
An Investigation of Middle School Students' Attitudes and Awareness of Water Use
ERIC Educational Resources Information Center
Aydogdu, Bülent; Çakir, Aysun
2016-01-01
The purpose of this mixed method study is to investigate middle school students' attitudes and awareness of water use. The quantitative data were collected through the administration of "Water Usage Questionnaire (WUQ)". The qualitative data were collected through semi structured interviews. In the study the stratified sampling method…
Study of Human Barriers upon Development of Virtual Disciplines at University of Isfahan
ERIC Educational Resources Information Center
Nikoonezhad, Sepideh; Nili, Mohammadreza; Esfahani, Ahmadreza Nasr
2015-01-01
The present study has been carried out to investigate the human barriers of developing virtual majors at Isfahan University; therefore, considering its objective, it is a functional research. It was conducted in combined (quantitative-qualitative) manner via descriptive survey method. In order to do the research, investigating the texts, interview…
A Quantitative Investigation of Prospective Teachers' Hopes and Their Motivational Forces
ERIC Educational Resources Information Center
Eren, Altay; Yesilbursa, Amanda
2017-01-01
The present study aimed to investigate the diverse aspects of prospective teachers' dispositional hopes, teaching-specific hopes, and their sources, as well as to explore whether these would significantly predict their preparation for the teaching profession. A total of 851 prospective teachers voluntarily participated in the study. A series of…
ERIC Educational Resources Information Center
Aldegether, Reem
2017-01-01
This exploratory quantitative research investigated how "women's ways of knowing" (WWK) apply to female Saudi student teachers, and aimed to provide a useful contribution for further prospective study about this subject. The study used the Attitudes to Thinking and Learning Survey (ATTLS) questionnaire to investigate two such ways of…
Investigating the Benefits and Challenges of Using Laptop Computers in Higher Education Classrooms
ERIC Educational Resources Information Center
Kay, Robin Holding; Lauricella, Sharon
2014-01-01
The purpose of this study was to investigate the benefits and challenges using laptop computers (hereafter referred to as laptops) inside and outside higher education classrooms. Quantitative and qualitative data were collected from 156 university students (54 males, 102 females) enrolled in either education or communication studies. Benefits of…
Sasai-Sakuma, Taeko; Frauscher, Birgit; Mitterling, Thomas; Ehrmann, Laura; Gabelia, David; Brandauer, Elisabeth; Inoue, Yuichi; Poewe, Werner; Högl, Birgit
2014-09-01
Rapid eye movement (REM) sleep without atonia (RWA) is observed in some patients without a clinical history of REM sleep behavior disorder (RBD). It remains unknown whether these patients meet the refined quantitative electromyographic (EMG) criteria supporting a clinical RBD diagnosis. We quantitatively evaluated EMG activity and investigated its overnight distribution in patients with isolated qualitative RWA. Fifty participants with an incidental polysomnographic finding of RWA (isolated qualitative RWA) were included. Tonic, phasic, and 'any' EMG activity during REM sleep on PSG were quantified retrospectively. Referring to the quantitative cut-off values for a polysomnographic diagnosis of RBD, 7/50 (14%) and 6/50 (12%) of the patients showed phasic and 'any' EMG activity in the mentalis muscle above the respective cut-off values. No patient was above the cut-off value for tonic EMG activity or phasic EMG activity in the anterior tibialis muscles. Patients with RWA above the cut-off value showed higher amounts of RWA during later REM sleep periods. This is the first study showing that some subjects with incidental RWA meet the refined quantitative EMG criteria for a diagnosis of RBD. Future longitudinal studies must investigate whether this subgroup with isolated qualitative RWA is at an increased risk of developing fully expressed RBD and/or neurodegenerative disease. Copyright © 2014 Elsevier B.V. All rights reserved.
Paquette, Philippe; El Khamlichi, Youssef; Lamontagne, Martin; Higgins, Johanne; Gagnon, Dany H
2017-08-01
Quantitative ultrasound imaging is gaining popularity in research and clinical settings to measure the neuromechanical properties of the peripheral nerves such as their capability to glide in response to body segment movement. Increasing evidence suggests that impaired median nerve longitudinal excursion is associated with carpal tunnel syndrome. To date, psychometric properties of longitudinal nerve excursion measurements using quantitative ultrasound imaging have not been extensively investigated. This study investigates the convergent validity of the longitudinal nerve excursion by comparing measures obtained using quantitative ultrasound imaging with those determined with a motion analysis system. A 38-cm long rigid nerve-phantom model was used to assess the longitudinal excursion in a laboratory environment. The nerve-phantom model, immersed in a 20-cm deep container filled with a gelatin-based solution, was moved 20 times using a linear forward and backward motion. Three light-emitting diodes were used to record nerve-phantom excursion with a motion analysis system, while a 5-cm linear transducer allowed simultaneous recording via ultrasound imaging. Both measurement techniques yielded excellent association ( r = 0.99) and agreement (mean absolute difference between methods = 0.85 mm; mean relative difference between methods = 7.48 %). Small discrepancies were largely found when larger excursions (i.e. > 10 mm) were performed, revealing slight underestimation of the excursion by the ultrasound imaging analysis software. Quantitative ultrasound imaging is an accurate method to assess the longitudinal excursion of an in vitro nerve-phantom model and appears relevant for future research protocols investigating the neuromechanical properties of the peripheral nerves.
Self-Regulated Learning in Virtual Communities
ERIC Educational Resources Information Center
Delfino, Manuela; Dettori, Giuliana; Persico, Donatella
2008-01-01
This paper investigates self-regulated learning (SRL) in a virtual learning community of adults interacting through asynchronous textual communication. The investigation method chosen is interaction analysis, a qualitative/quantitative approach allowing a systematic study of the contents of the messages exchanged within online communities. The…
ERIC Educational Resources Information Center
Binkley, Zachary Wayne McClellan
2017-01-01
This study investigates computer self-efficacy and computer anxiety within 61 students across two academic majors, Aviation and Sports and Exercise Science, while investigating the impact residential status, age, and gender has on those two psychological constructs. The purpose of the study is to find if computer self-efficacy and computer anxiety…
ERIC Educational Resources Information Center
Vallin, Marlene Boyd
A study analyzed quantitatively the effectiveness of public communication as practiced by college students in an introductory speech course. The aim of the study was to test empirically the principles of rhetorical theory on which the teaching of beginning public speaking is commonly based. The study investigated the relationship of mode of…
Sung, Kyung Mi; Bernstein, Kunsook
2017-12-01
This study extends Bernstein et al.'s (2016) investigation of the effects of the Enhanced Logo-autobiography Program on Korean-American women's depressive symptoms, coping strategies, purpose in life, and posttraumatic growth by analyzing quantitative and qualitative data. This study's participants significantly improved on quantitative measures of depression, coping strategies, purpose in life, and post-traumatic growth at eight weeks post-intervention and follow-up. The qualitative content analysis revealed 17 themes with five essential themes. The program's activity to promote purpose in life through posttraumatic growth facilitated participants' recovery from traumatic experiences. Standardized guidelines are needed to conduct this program in Korean community centers.
Genetics and child psychiatry: I Advances in quantitative and molecular genetics.
Rutter, M; Silberg, J; O'Connor, T; Simonoff, E
1999-01-01
Advances in quantitative psychiatric genetics as a whole are reviewed with respect to conceptual and methodological issues in relation to statistical model fitting, new genetic designs, twin and adoptee studies, definition of the phenotype, pervasiveness of genetic influences, pervasiveness of environmental influences, shared and nonshared environmental effects, and nature-nurture interplay. Advances in molecular genetics are discussed in relation to the shifts in research strategies to investigate multifactorial disorders (affected relative linkage designs, association strategies, and quantitative trait loci studies); new techniques and identified genetic mechanisms (expansion of trinucleotide repeats, genomic imprinting, mitochondrial DNA, fluorescent in-situ hybridisation, behavioural phenotypes, and animal models); and the successful localisation of genes.
NASA Astrophysics Data System (ADS)
Udokwu, Chukwudi John
This study utilized mixed methodology of quantitative and qualitative research approach to explore the current pedagogical engagements of twenty middle school urban science teachers in the Midwest region of the United States. It qualitatively examined twelve of these teachers' knowledge of culturally responsive pedagogy. The study investigated the following questions: What are the current pedagogical practices of urban middle school science teachers? To what extent are middle school science teachers' pedagogical practices in urban schools culturally responsive? What are urban students' perspectives of their teachers' current pedagogical engagements? The design of the study was qualitative and quantitative methods in order to investigate these teachers' pedagogical practices. Data collections were drawn from multiple sources such as lesson plans, students' sample works, district curriculum, surveys, observational and interview notes. Analysis of collected data was a mixed methodology that involved qualitative and quantitative methods using descriptive, interpretative, pattern codes, and statistical procedures respectively. Purposeful sampling was selected for this study. Thus, demographically there were twenty participants who quantitatively took part in this study. Among them were seven (35%) males and thirteen (65%) females, three (15%) African Americans and seventeen (85%) Caucasians. In determining to what extent urban science teachers' pedagogical practices were culturally responsive, eight questions were analyzed based on four cluster themes: (a) teachers' social disposition, (b) culturally responsive curriculum, (c) classroom interactions, and (d) power pedagogy. Study result revealed that only five (25%) of the participants were engaged in culturally responsive pedagogy while fifteen (75%) were engaged in what Haberman (1991) called the pedagogy of poverty. The goal was to investigate urban science teachers' pedagogical engagements and to examine urban students' perspective of their science teachers' pedagogical practices, and ensure that all students have a sense of ownership of their knowledge, a sense that is empowering and liberating. The implications of these findings were to promote urban students' achievements in science and see them employed in science and engineering. I hope this study helps in developing better professional development that will be culturally responsive and to ensure that all students have a sense of ownership of their knowledge.
Study On The Application Of CBERS-02B To Quantitative Soil Erosion Monitoring
NASA Astrophysics Data System (ADS)
Shi, Mingchang; Xu, Jing; Wang, Lei; Wang, Xiaoyun; Mu, Jing
2010-10-01
Currently, the reduction of soil erosion is an important prerequisite for achieving ecological security. Since real-time and quantitative evaluation on regional soil erosion plays a significant role in reducing the soil erosion, soil erosion models are more and more widely used. Based on RUSLE model, this paper carries out the quantitative soil erosion monitoring in the Xi River Basin and its surrounding areas by using CBERS-02B CCD, DEM, TRMM and other data. Besides, it performs the validation for monitoring results by using remote sensing investigation results in 2005. The monitoring results show that in 2009, the total amount of soil erosion in the study area was 1.94×106t, the erosion area was 2055.2km2 (54.06% of the total area), and the average soil erosion modulus was 509.7t km-2 a-1. As a case using CBERS-02B data for quantitative soil erosion monitoring, this study provides experience on the application of CBERS-02B data in the field of quantitative soil erosion monitoring and also for local soil erosion management.
Su, Yi; Blazey, Tyler M; Owen, Christopher J; Christensen, Jon J; Friedrichsen, Karl; Joseph-Mathurin, Nelly; Wang, Qing; Hornbeck, Russ C; Ances, Beau M; Snyder, Abraham Z; Cash, Lisa A; Koeppe, Robert A; Klunk, William E; Galasko, Douglas; Brickman, Adam M; McDade, Eric; Ringman, John M; Thompson, Paul M; Saykin, Andrew J; Ghetti, Bernardino; Sperling, Reisa A; Johnson, Keith A; Salloway, Stephen P; Schofield, Peter R; Masters, Colin L; Villemagne, Victor L; Fox, Nick C; Förster, Stefan; Chen, Kewei; Reiman, Eric M; Xiong, Chengjie; Marcus, Daniel S; Weiner, Michael W; Morris, John C; Bateman, Randall J; Benzinger, Tammie L S
2016-01-01
Amyloid imaging plays an important role in the research and diagnosis of dementing disorders. Substantial variation in quantitative methods to measure brain amyloid burden exists in the field. The aim of this work is to investigate the impact of methodological variations to the quantification of amyloid burden using data from the Dominantly Inherited Alzheimer's Network (DIAN), an autosomal dominant Alzheimer's disease population. Cross-sectional and longitudinal [11C]-Pittsburgh Compound B (PiB) PET imaging data from the DIAN study were analyzed. Four candidate reference regions were investigated for estimation of brain amyloid burden. A regional spread function based technique was also investigated for the correction of partial volume effects. Cerebellar cortex, brain-stem, and white matter regions all had stable tracer retention during the course of disease. Partial volume correction consistently improves sensitivity to group differences and longitudinal changes over time. White matter referencing improved statistical power in the detecting longitudinal changes in relative tracer retention; however, the reason for this improvement is unclear and requires further investigation. Full dynamic acquisition and kinetic modeling improved statistical power although it may add cost and time. Several technical variations to amyloid burden quantification were examined in this study. Partial volume correction emerged as the strategy that most consistently improved statistical power for the detection of both longitudinal changes and across-group differences. For the autosomal dominant Alzheimer's disease population with PiB imaging, utilizing brainstem as a reference region with partial volume correction may be optimal for current interventional trials. Further investigation of technical issues in quantitative amyloid imaging in different study populations using different amyloid imaging tracers is warranted.
Su, Yi; Blazey, Tyler M.; Owen, Christopher J.; Christensen, Jon J.; Friedrichsen, Karl; Joseph-Mathurin, Nelly; Wang, Qing; Hornbeck, Russ C.; Ances, Beau M.; Snyder, Abraham Z.; Cash, Lisa A.; Koeppe, Robert A.; Klunk, William E.; Galasko, Douglas; Brickman, Adam M.; McDade, Eric; Ringman, John M.; Thompson, Paul M.; Saykin, Andrew J.; Ghetti, Bernardino; Sperling, Reisa A.; Johnson, Keith A.; Salloway, Stephen P.; Schofield, Peter R.; Masters, Colin L.; Villemagne, Victor L.; Fox, Nick C.; Förster, Stefan; Chen, Kewei; Reiman, Eric M.; Xiong, Chengjie; Marcus, Daniel S.; Weiner, Michael W.; Morris, John C.; Bateman, Randall J.; Benzinger, Tammie L. S.
2016-01-01
Amyloid imaging plays an important role in the research and diagnosis of dementing disorders. Substantial variation in quantitative methods to measure brain amyloid burden exists in the field. The aim of this work is to investigate the impact of methodological variations to the quantification of amyloid burden using data from the Dominantly Inherited Alzheimer’s Network (DIAN), an autosomal dominant Alzheimer’s disease population. Cross-sectional and longitudinal [11C]-Pittsburgh Compound B (PiB) PET imaging data from the DIAN study were analyzed. Four candidate reference regions were investigated for estimation of brain amyloid burden. A regional spread function based technique was also investigated for the correction of partial volume effects. Cerebellar cortex, brain-stem, and white matter regions all had stable tracer retention during the course of disease. Partial volume correction consistently improves sensitivity to group differences and longitudinal changes over time. White matter referencing improved statistical power in the detecting longitudinal changes in relative tracer retention; however, the reason for this improvement is unclear and requires further investigation. Full dynamic acquisition and kinetic modeling improved statistical power although it may add cost and time. Several technical variations to amyloid burden quantification were examined in this study. Partial volume correction emerged as the strategy that most consistently improved statistical power for the detection of both longitudinal changes and across-group differences. For the autosomal dominant Alzheimer’s disease population with PiB imaging, utilizing brainstem as a reference region with partial volume correction may be optimal for current interventional trials. Further investigation of technical issues in quantitative amyloid imaging in different study populations using different amyloid imaging tracers is warranted. PMID:27010959
ERIC Educational Resources Information Center
Kuhn, Matthew Scott
2012-01-01
The purpose of this descriptive quantitative study was to investigate possible differences in school leadership within a change process, as perceived by teachers. Grouped by generation, this study investigated principals' perceptions of change order and that of their teachers, as well as how their teachers perceived their principal's leadership…
ERIC Educational Resources Information Center
Johnson, Heather Lynn
2015-01-01
Contributing to a growing body of research addressing secondary students' quantitative and covariational reasoning, the multiple case study reported in this article investigated secondary students' quantification of ratio and rate. This article reports results from a study investigating students' quantification of rate and ratio as…
The Power of Natural Selection: A Guided Investigation of Three Case Studies
ERIC Educational Resources Information Center
Beachly, William
2010-01-01
I describe a quantitative approach to three case studies in evolution that can be used to challenge college freshmen to explore the power of natural selection and ask questions that foster a deeper understanding of its operation and relevance. Hemochromatosis, the peppered moth, and hominid cranial capacity are investigated with a common algebraic…
High School Principals' Rating of Success in Implementation of 21st Century Skills
ERIC Educational Resources Information Center
Sam, Sonn
2011-01-01
The purpose of this quantitative study was to investigate how Rhode Island high school principals rate success in implementing 21st century skills in their schools. Secondly, this study investigated how high school principals rate the influence of implementing of 21st century skills in curriculum and instruction in their schools. The high…
ERIC Educational Resources Information Center
Martin, Andrew J.; Papworth, Brad; Ginns, Paul; Liem, Gregory Arief D.
2014-01-01
Boarding school has been a feature of education systems for centuries. Minimal large-scale quantitative data have been collected to examine its association with important educational and other outcomes. The present study represents one of the largest studies into boarding school conducted to date. It investigates boarding school and students'…
Quantitative Reasoning in Environmental Science: A Learning Progression
ERIC Educational Resources Information Center
Mayes, Robert Lee; Forrester, Jennifer Harris; Christus, Jennifer Schuttlefield; Peterson, Franziska Isabel; Bonilla, Rachel; Yestness, Nissa
2014-01-01
The ability of middle and high school students to reason quantitatively within the context of environmental science was investigated. A quantitative reasoning (QR) learning progression was created with three progress variables: quantification act, quantitative interpretation, and quantitative modeling. An iterative research design was used as it…
OREL, NANCY A.
2014-01-01
Extensive research on the specific needs and concerns of lesbian, gay, bisexual, and transgender (LGBT) older adults is lacking. This article describes the results of both quantitative studies (i.e., LGBT Elders Needs Assessment Scale) and qualitative studies (i.e., focus groups and in-depth interviews with lesbian, gay, or bisexual [LGB] older adults and LGB grandparents) that specifically sought to investigate the unique needs and concerns of LGBT elders. The results identified 7 areas (medical/health care, legal, institutional/housing, spiritual, family, mental health, and social) of concern and the recognition that the needs and concerns of LGBT older adults be addressed across multiple domains, rather than in isolation. PMID:24313253
Lorentz, Madeline; Finnegan, Brittany
2013-01-01
This study examined whether an agency's investigation of complaints in 40 nursing homes is positively correlated with the quality of nursing home care. A quantitative methodology design using quantitative and qualitative data was used to assess the relationship between Agency X's investigation of consumers' nursing home complaints and the quality of nursing home care. Results showed fewer violations after the agency's interventions, indicating improvement in the nursing care. Analysis showed on average 0.14 fewer violations. This decrease is statistically significant (p = .015), indicating that this agency's intervention improved nursing home care. Additional studies are needed to further explore the quality of care given in nursing homes. Nurses may propose to the Centers for Medicare & Medicaid Services to establish a new innovative system for ensuring high quality nursing home care by requiring the establishment of outside agencies, such as Agency X, to monitor care in addition to the annual surveys conducted by the Department of Health and Human Services. © 2013 Wiley Periodicals, Inc.
NASA Astrophysics Data System (ADS)
Singh, Vijay Raj; Yaqoob, Zahid; So, Peter T. C.
2017-02-01
Quantitative phase microscopy (QPM) techniques developed so far primarily belongs to high speed transmitted light based systems that has enough sensitivity to resolve membrane fluctuations and dynamics, but has no depth resolution. Therefore, most biomechanics studies using QPM today is confined to simple cells, such as RBCs, without internal organelles. An important instrument that will greatly extend the biomedical applications of QPM is to develop next generation microscope with 3D capability and sufficient temporal resolution to study biomechanics of complex eukaryotic cells including the mechanics of their internal compartments. For eukaryotic cells, the depth sectioning capability is critical and should be sufficient to distinguish nucleic membrane fluctuations from plasma membrane fluctuations. Further, this microscope must provide high temporal resolution since typical eukaryotes membranes are substantially stiffer than RBCs. A confocal reflectance quantitative phase microscope is presented based on multi-pinhole scanning, with the capabilities of higher temporal resolution and sensitivity for nucleic and plasma membranes of eukaryotic cells. System hardware is developed based on an array of confocal pinhole generated by using the `ON' state of subset of micro-mirrors of digital micro-mirror device (DMD, from Texas Instruments) and high-speed raster scanning provides 14ms imaging speed in wide-field mode. A common path interferometer is integrated at the imaging arm for detection of specimens' quantitative phase information. Theoretical investigation of quantitative phase reconstructed from system is investigated and application of system is presented for dimensional fluctuations measurements of both cellular plasma and nucleic membranes of embryonic stem cells.
Digital Holography, a metrological tool for quantitative analysis: Trends and future applications
NASA Astrophysics Data System (ADS)
Paturzo, Melania; Pagliarulo, Vito; Bianco, Vittorio; Memmolo, Pasquale; Miccio, Lisa; Merola, Francesco; Ferraro, Pietro
2018-05-01
A review on the last achievements of Digital Holography is reported in this paper, showing that this powerful method can be a key metrological tool for the quantitative analysis and non-invasive inspection of a variety of materials, devices and processes. Nowadays, its range of applications has been greatly extended, including the study of live biological matter and biomedical applications. This paper overviews the main progresses and future perspectives of digital holography, showing new optical configurations and investigating the numerical issues to be tackled for the processing and display of quantitative data.
Reischer, G H; Haider, J M; Sommer, R; Stadler, H; Keiblinger, K M; Hornek, R; Zerobin, W; Mach, R L; Farnleitner, A H
2008-10-01
The impairment of water quality by faecal pollution is a global public health concern. Microbial source tracking methods help to identify faecal sources but the few recent quantitative microbial source tracking applications disregarded catchment hydrology and pollution dynamics. This quantitative microbial source tracking study, conducted in a large karstic spring catchment potentially influenced by humans and ruminant animals, was based on a tiered sampling approach: a 31-month water quality monitoring (Monitoring) covering seasonal hydrological dynamics and an investigation of flood events (Events) as periods of the strongest pollution. The detection of a ruminant-specific and a human-specific faecal Bacteroidetes marker by quantitative real-time PCR was complemented by standard microbiological and on-line hydrological parameters. Both quantitative microbial source tracking markers were detected in spring water during Monitoring and Events, with preponderance of the ruminant-specific marker. Applying multiparametric analysis of all data allowed linking the ruminant-specific marker to general faecal pollution indicators, especially during Events. Up to 80% of the variation of faecal indicator levels during Events could be explained by ruminant-specific marker levels proving the dominance of ruminant faecal sources in the catchment. Furthermore, soil was ruled out as a source of quantitative microbial source tracking markers. This study demonstrates the applicability of quantitative microbial source tracking methods and highlights the prerequisite of considering hydrological catchment dynamics in source tracking study design.
Campbell, David J T; Tam-Tham, Helen; Dhaliwal, Kirnvir K; Manns, Braden J; Hemmelgarn, Brenda R; Sanmartin, Claudia; King-Shier, Kathryn
2017-01-01
Mixed methods research, the use of both qualitative and quantitative methods within 1 program of study, is becoming increasingly popular to allow investigators to explore patient experiences (qualitative) and also measure outcomes (quantitative). Coronary artery disease and its risk factors are some of the most studied conditions; however, the extent to which mixed methods studies are being conducted in these content areas is unknown. We sought to comprehensively describe the characteristics of published mixed methods studies on coronary artery disease and major risk factors (diabetes mellitus and hypertension). We conducted a scoping review of the literature indexed in PubMed, Medline, EMBASE, and CINAHL. We identified 811 abstracts for screening, of which 254 articles underwent full-text review and 97 reports of 81 studies met criteria for inclusion. The majority of studies in this area were conducted in the past 10 years by nurse researchers from the United States and United Kingdom. Diabetes mellitus was the most common content area for mixed methods investigation (compared with coronary artery disease and hypertension). Most authors described their rationale for using mixed methods as complementarity and did not describe study priority or how they reconciled differences in methodological paradigms. Some mixed methods study designs were more commonly used than others, including concurrent timing and integration at the interpretation stage. Qualitative strands were most commonly descriptive studies using interviews for data collection. Quantitative strands were most commonly cross-sectional observational studies, which relied heavily on self-report data such as surveys and scales. Although mixed methods research is becoming increasingly popular in the area of coronary artery disease and its risk factors, many of the more advanced mixed methods, qualitative, and quantitative techniques have not been commonly used in these areas. © 2016 American Heart Association, Inc.
Effectiveness of Facebook in English Language Learning: A Case Study
ERIC Educational Resources Information Center
Faryadi, Qais
2017-01-01
The prime objective of this research was to investigate whether Facebook helped undergraduate students of Universiti Sains Islam Malaysia (USIM) improve their English language proficiency, critical thinking, comprehension skills, and motivation. A triangulation method (quantitative, qualitative, and descriptive) was employed in the investigation.…
ERIC Educational Resources Information Center
Yousef, Darwish Abdulrahman
2011-01-01
This article aims to investigate the academic performance (measured by quality points) of the business students in quantitative courses. It also explores the impact of a number of factors on the academic performance of business students in these courses. A random sample of 750 third- and fourth-level business students at the United Arab Emirates…
Comparison of Quantitative Antifungal Testing Methods for Textile Fabrics.
Imoto, Yasuo; Seino, Satoshi; Nakagawa, Takashi; Yamamoto, Takao A
2017-01-01
Quantitative antifungal testing methods for textile fabrics under growth-supportive conditions were studied. Fungal growth activities on unfinished textile fabrics and textile fabrics modified with Ag nanoparticles were investigated using the colony counting method and the luminescence method. Morphological changes of the fungi during incubation were investigated by microscopic observation. Comparison of the results indicated that the fungal growth activity values obtained with the colony counting method depended on the morphological state of the fungi on textile fabrics, whereas those obtained with the luminescence method did not. Our findings indicated that unique characteristics of each testing method must be taken into account for the proper evaluation of antifungal activity.
The experiences of relatives with the practice of palliative sedation: a systematic review.
Bruinsma, Sophie M; Rietjens, Judith A C; Seymour, Jane E; Anquinet, Livia; van der Heide, Agnes
2012-09-01
Guidelines about palliative sedation typically include recommendations to protect the well-being of relatives. The aim of this study was to systematically review evidence on the experiences of relatives with the practice of palliative sedation. PubMed, Embase, Web of Science, PsycINFO, and CINAHL were searched for empirical studies on relatives' experiences with palliative sedation. We investigated relatives' involvement in the decision-making and sedation processes, whether they received adequate information and support, and relatives' emotions. Of the 564 studies identified, 39 were included. The studies (30 quantitative, six qualitative, and three mixed methods) were conducted in 16 countries; three studies were based on relatives' reports, 26 on physicians' and nurses' proxy reports, seven on medical records, and three combined different sources. The 39 studies yielded a combined total of 8791 respondents or studied cases. Caregivers involved relatives in the decision making in 69%-100% of all cases (19 quantitative studies), and in 60%-100% of all cases, relatives were reported to have received adequate information (five quantitative studies). Only two quantitative studies reported on relatives' involvement in the provision of sedation. Despite the fact that the majority of relatives were reported to be comfortable with the use of palliative sedation (seven quantitative studies, four qualitative studies), several studies found that relatives were distressed by the use of sedation (five quantitative studies, five qualitative studies). No studies reported specifically about the support provided to the relatives. Relatives' experiences with palliative sedation are mainly studied from the perspective of proxies, mostly professional caregivers. The majority of relatives seems to be comfortable with the use of palliative sedation; however, they may experience substantial distress by the use of sedation. Copyright © 2012 U.S. Cancer Pain Relief Committee. Published by Elsevier Inc. All rights reserved.
ERIC Educational Resources Information Center
Ashraf, Hamid; Ahmadi, Fatemeh; Hosseinnia, Mansooreh
2017-01-01
The present study intended to integrate some 21st century skills teaching into English classroom and investigate their effect on listening and reading comprehension skills. In so doing, the study used a quantitative, experimental design with 55 participants, 25 in the control group and 30 in the experimental group who were students of second high…
ERIC Educational Resources Information Center
Li, Yi
2012-01-01
This study focuses on the issue of learning equity in colleges and universities where teaching and learning have come to depend heavily on computer technologies. The study uses the Multiple Indicators Multiple Causes (MIMIC) latent variable model to quantitatively investigate whether there is a gender /ethnicity difference in using computer based…
ERIC Educational Resources Information Center
Arslan, Yusuf
2016-01-01
In this study, it was tried to comprehend whether there occur any changes in behaviours of university students switching from classical cell phones to smartphones. The investigation was carried out according to quantitative research method. Questionnaire was employed as data collection tool. The datum of the study was limited with the information…
Jääskeläinen, Satu K
2004-01-01
Chronic orofacial pain represents a diagnostic and treatment challenge for the clinician. Some conditions, such as atypical facial pain, still lack proper diagnostic criteria, and their etiology is not known. The recent development of neurophysiological methods and quantitative sensory testing for the examination of the trigeminal somatosensory system offers several tools for diagnostic and etiological investigation of orofacial pain. This review presents some of these techniques and the results of their application in studies on orofacial pain and sensory dysfunction. Clinical neurophysiological investigation has greater diagnostic accuracy and sensitivity than clinical examination in the detection of the neurogenic abnormalities of either peripheral or central origin that may underlie symptoms of orofacial pain and sensory dysfunction. Neurophysiological testing may also reveal trigeminal pathology when magnetic resonance imaging has failed to detect it, so these methods should be considered complementary to each other in the investigation of orofacial pain patients. The blink reflex, corneal reflex, jaw jerk, sensory neurography of the inferior alveolar nerve, and the recording of trigeminal somatosensory-evoked potentials with near-nerve stimulation have all proved to be sensitive and reliable in the detection of dysfunction of the myelinated sensory fibers of the trigeminal nerve or its central connections within the brainstem. With appropriately small thermodes, thermal quantitative sensory testing is useful for the detection of trigeminal small-fiber dysfunction (Adelta and C). In neuropathic conditions, it is most sensitive to lesions causing axonal injury. By combining different techniques for investigation of the trigeminal system, an accurate topographical diagnosis and profile of sensory fiber pathology can be determined. Neurophysiological and quantitative sensory tests have already highlighted some similarities among various orofacial pain conditions and have shown heterogeneity within clinical diagnostic categories. With the aid of neurophysiological recordings and quantitative sensory testing, it is possible to approach a mechanism-based classification of orofacial pain.
Reviewing effectiveness of ankle assessment techniques for use in robot-assisted therapy.
Zhang, Mingming; Davies, T Claire; Zhang, Yanxin; Xie, Shane
2014-01-01
This article provides a comprehensive review of studies that investigated ankle assessment techniques to better understand those that can be used in the real-time monitoring of rehabilitation progress for implementation in conjunction with robot-assisted therapy. Seventy-six publications published between January 1980 and August 2013 were selected based on eight databases. They were divided into two main categories (16 qualitative and 60 quantitative studies): 13 goniometer studies, 18 dynamometer studies, and 29 studies about innovative techniques. A total of 465 subjects participated in the 29 quantitative studies of innovative measurement techniques that may potentially be integrated in a real-time monitoring device, of which 19 studies included less than 10 participants. Results show that qualitative ankle assessment methods are not suitable for real-time monitoring in robot-assisted therapy, though they are reliable for certain patients, while the quantitative methods show great potential. The majority of quantitative techniques are reliable in measuring ankle kinematics and kinetics but are usually available only for use in the sagittal plane. Limited studies determine kinematics and kinetics in all three planes (sagittal, transverse, and frontal) where motions of the ankle joint and the subtalar joint actually occur.
Chen, Bihua; Chen, Gang; Dai, Chenxi; Wang, Pei; Zhang, Lei; Huang, Yuanyuan; Li, Yongqin
2018-04-01
Quantitative electroencephalogram (EEG) analysis has shown promising results in studying brain injury and functional recovery after cardiac arrest (CA). However, whether the quantitative characteristics of EEG, as potential indicators of neurological prognosis, are influenced by CA causes is unknown. The purpose of this study was designed to compare the quantitative characteristics of early post-resuscitation EEG between asphyxial CA (ACA) and ventricular fibrillation CA (VFCA) in rats. Thirty-two Sprague-Dawley rats of both sexes were randomized into either ACA or VFCA group. Cardiopulmonary resuscitation was initiated after 5-min untreated CA. Characteristics of early post-resuscitation EEG were compared, and the relationships between quantitative EEG features and neurological outcomes were investigated. Compared with VFCA, serum level of S100B, neurological deficit score and brain histopathologic damage score were dramatically higher in the ACA group. Quantitative measures of EEG, including onset time of EEG burst, time to normal trace, burst suppression ratio, and information quantity, were significantly lower for CA caused by asphyxia and correlated with the 96-h neurological outcome and survival. Characteristics of earlier post-resuscitation EEG differed between cardiac and respiratory causes. Quantitative measures of EEG not only predicted neurological outcome and survival, but also have the potential to stratify CA with different causes.
Quantitative Investigations in Hungarian Phonotactics and Syllable Structure
ERIC Educational Resources Information Center
Grimes, Stephen M.
2010-01-01
This dissertation investigates statistical properties of segment collocation and syllable geometry of the Hungarian language. A corpus and dictionary based approach to studying language phonologies is outlined. In order to conduct research on Hungarian, a phonological lexicon was created by compiling existing dictionaries and corpora and using a…
Investigating Student Motivation and Performance in Electrical Engineering and Its Subdisciplines
ERIC Educational Resources Information Center
Foley, Justin M.; Daly, Shanna; Lenaway, Catherine; Phillips, Jamie
2016-01-01
Factors influencing choice of major in electrical engineering and later curricular and professional choices are investigated. Studies include both quantitative and qualitative analyses via student transcripts, surveys, and focus groups. Student motivation for choosing an electrical engineering major and later subdiscipline in the field is…
An Investigation of Factors Impacting the Wellness of Academic Library Employees
ERIC Educational Resources Information Center
Lo, Leo S.; Herman, Bethany
2017-01-01
The term "wellness" is fast garnering attention on how it affects one's professional and personal life. This study explores the multi-dimensions of wellness and investigates factors that might impact the "wellness" of employees in academic libraries. The research topic was addressed through quantitative analyses of responses to…
Investigation of Millennial Students' Responses to a Shelter-in-Place Experience
ERIC Educational Resources Information Center
Johnson, Thomas C.; Frick, Melodie H.
2016-01-01
This study investigated millennial students' responses to an armed gunman threat and shelter-in-place warnings that occurred on a university campus. Using descriptive statistics and quantitative analysis, several significant differences were found for students' responses for sheltering-in-place and engaging in protective behaviors. Baxter Magolda'…
Ammitzbøll-Danielsen, Mads; Østergaard, Mikkel; Naredo, Esperanza; Terslev, Lene
2016-12-01
The aim was to evaluate the metric properties of the semi-quantitative OMERACT US scoring system vs a novel quantitative US scoring system for tenosynovitis, by testing its intra- and inter-reader reliability, sensitivity to change and comparison with clinical tenosynovitis scoring in a 6-month follow-up study. US and clinical assessments of the tendon sheaths of the clinically most affected hand and foot were performed at baseline, 3 and 6 months in 51 patients with RA. Tenosynovitis was assessed using the semi-quantitative scoring system (0-3) proposed by the OMERACT US group and a new quantitative US evaluation (0-100). A sum for US grey scale (GS), colour Doppler (CD) and pixel index (PI), respectively, was calculated for each patient. In 20 patients, intra- and inter-observer agreement was established between two independent investigators. A binary clinical tenosynovitis score was performed, calculating a sum score per patient. The intra- and inter-observer agreements for US tenosynovitis assessments were very good at baseline and for change for GS and CD, but less good for PI. The smallest detectable change was 0.97 for GS, 0.93 for CD and 30.1 for PI. The sensitivity to change from month 0 to 6 was high for GS and CD, and slightly higher than for clinical tenosynovitis score and PI. This study demonstrated an excellent intra- and inter-reader agreement between two investigators for the OMERACT US scoring system for tenosynovitis and a high ability to detect changes over time. Quantitative assessment by PI did not add further information. © The Author 2016. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.
ERIC Educational Resources Information Center
Aksakalli, Ayhan; Salar, Riza; Turgut, Umit
2016-01-01
In this research, the negative perceptions of undergraduate students regarding modern physics course and the causes of their negative perceptions have been investigated. For this investigation, a qualitative and quantitative method (mix method) was chosen for data collection and analysis. The study group of the research consists of a total of 169…
ERIC Educational Resources Information Center
Aghababaeian, Parinaz; Moghaddam, Shams Aldin Hashemi; Nateghi, Faezeh; Faghihi, Alireza
2017-01-01
This study investigated the changes in public school social studies textbooks in general period of Iran (fourth and fifth grades) based on the emphasis on Facione critical thinking skills in the past three decades. In this study, content analysis of qualitative and quantitative methods was used to evaluate changes in textbook. For this purpose,…
Quantitative proteomics in biological research.
Wilm, Matthias
2009-10-01
Proteomics has enabled the direct investigation of biological material, at first through the analysis of individual proteins, then of lysates from cell cultures, and finally of extracts from tissues and biopsies from entire organisms. Its latest manifestation - quantitative proteomics - allows deeper insight into biological systems. This article reviews the different methods used to extract quantitative information from mass spectra. It follows the technical developments aimed toward global proteomics, the attempt to characterize every expressed protein in a cell by at least one peptide. When applications of the technology are discussed, the focus is placed on yeast biology. In particular, differential quantitative proteomics, the comparison between an experiment and its control, is very discriminating for proteins involved in the process being studied. When trying to understand biological processes on a molecular level, differential quantitative proteomics tends to give a clearer picture than global transcription analyses. As a result, MS has become an even more indispensable tool for biochemically motivated biological research.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Beck, R.N.; Cooper, M.D.
1984-09-01
This report presents progress in the areas of cardiac nuclear medicine, other imaging studies, investigations with biomolecules, and assessment of risks associated with the clinical use of radiopharmaceuticals. (ACR)
Holzweber, Markus; Lippitz, Andreas; Krueger, Katharina; Jankowski, Joachim; Unger, Wolfgang E S
2015-03-24
The surfaces of polymeric dialyzer membranes consisting of polysulfone and polyvinylpyrrolidone were investigated regarding the lateral distribution and quantitative surface composition using time-of-flight secondary-ion-mass-spectrometry and x-ray photoelectron spectroscopy. Knowledge of the distribution and composition on the outer surface region is of utmost importance for understanding the biocompatibility of such dialyzer membranes. Both flat membranes and hollow fiber membranes were studied.
Optical coherence tomography for the quantitative study of cerebrovascular physiology
Srinivasan, Vivek J; Atochin, Dmitriy N; Radhakrishnan, Harsha; Jiang, James Y; Ruvinskaya, Svetlana; Wu, Weicheng; Barry, Scott; Cable, Alex E; Ayata, Cenk; Huang, Paul L; Boas, David A
2011-01-01
Doppler optical coherence tomography (DOCT) and OCT angiography are novel methods to investigate cerebrovascular physiology. In the rodent cortex, DOCT flow displays features characteristic of cerebral blood flow, including conservation along nonbranching vascular segments and at branch points. Moreover, DOCT flow values correlate with hydrogen clearance flow values when both are measured simultaneously. These data validate DOCT as a noninvasive quantitative method to measure tissue perfusion over a physiologic range. PMID:21364599
Quantitative Detection of Cracks in Steel Using Eddy Current Pulsed Thermography.
Shi, Zhanqun; Xu, Xiaoyu; Ma, Jiaojiao; Zhen, Dong; Zhang, Hao
2018-04-02
Small cracks are common defects in steel and often lead to catastrophic accidents in industrial applications. Various nondestructive testing methods have been investigated for crack detection; however, most current methods focus on qualitative crack identification and image processing. In this study, eddy current pulsed thermography (ECPT) was applied for quantitative crack detection based on derivative analysis of temperature variation. The effects of the incentive parameters on the temperature variation were analyzed in the simulation study. The crack profile and position are identified in the thermal image based on the Canny edge detection algorithm. Then, one or more trajectories are determined through the crack profile in order to determine the crack boundary through its temperature distribution. The slope curve along the trajectory is obtained. Finally, quantitative analysis of the crack sizes was performed by analyzing the features of the slope curves. The experimental verification showed that the crack sizes could be quantitatively detected with errors of less than 1%. Therefore, the proposed ECPT method was demonstrated to be a feasible and effective nondestructive approach for quantitative crack detection.
ERIC Educational Resources Information Center
Fisher, Paula V.
2010-01-01
This study was an investigation of a community college child development centers' leadership best practices and center teacher morale. A review of the literature focused on high and low teacher morale and leadership best practices. This quantitative study was conducted using the survey-design method with an adapted version of the Purdue Teacher…
Quantitative analysis of the evolution of novelty in cinema through crowdsourced keywords.
Sreenivasan, Sameet
2013-09-26
The generation of novelty is central to any creative endeavor. Novelty generation and the relationship between novelty and individual hedonic value have long been subjects of study in social psychology. However, few studies have utilized large-scale datasets to quantitatively investigate these issues. Here we consider the domain of American cinema and explore these questions using a database of films spanning a 70 year period. We use crowdsourced keywords from the Internet Movie Database as a window into the contents of films, and prescribe novelty scores for each film based on occurrence probabilities of individual keywords and keyword-pairs. These scores provide revealing insights into the dynamics of novelty in cinema. We investigate how novelty influences the revenue generated by a film, and find a relationship that resembles the Wundt-Berlyne curve. We also study the statistics of keyword occurrence and the aggregate distribution of keywords over a 100 year period.
Quantitative analysis of the evolution of novelty in cinema through crowdsourced keywords
Sreenivasan, Sameet
2013-01-01
The generation of novelty is central to any creative endeavor. Novelty generation and the relationship between novelty and individual hedonic value have long been subjects of study in social psychology. However, few studies have utilized large-scale datasets to quantitatively investigate these issues. Here we consider the domain of American cinema and explore these questions using a database of films spanning a 70 year period. We use crowdsourced keywords from the Internet Movie Database as a window into the contents of films, and prescribe novelty scores for each film based on occurrence probabilities of individual keywords and keyword-pairs. These scores provide revealing insights into the dynamics of novelty in cinema. We investigate how novelty influences the revenue generated by a film, and find a relationship that resembles the Wundt-Berlyne curve. We also study the statistics of keyword occurrence and the aggregate distribution of keywords over a 100 year period. PMID:24067890
Eliciting women's cervical screening preferences: a mixed methods systematic review protocol.
Wood, Brianne; Van Katwyk, Susan Rogers; El-Khatib, Ziad; McFaul, Susan; Taljaard, Monica; Wright, Erica; Graham, Ian D; Little, Julian
2016-08-11
With the accumulation of evidence regarding potential harms of cancer screening in recent years, researchers, policy-makers, and the public are becoming more critical of population-based cancer screening. Consequently, a high-quality cancer screening program should consider individuals' values and preferences when determining recommendations. In cervical cancer screening, offering women autonomy is considered a "person-centered" approach to health care services; however, it may impact the effectiveness of the program should women choose to not participate. As part of a larger project to investigate women's cervical screening preferences and correlates of these preferences, this systematic review will capture quantitative and qualitative investigations of women's cervical screening preferences and the methods used to elicit them. This mixed methods synthesis will use a thematic analysis approach to synthesize qualitative, quantitative, and mixed methods evidence. This protocol describes the methods that will be used in this investigation. A search strategy has been developed with a health librarian and peer reviewed using PRESS. Based on this strategy, five databases and the gray literature will be searched for studies that meet the inclusion criteria. The quality of the included individual studies will be examined using the Mixed Methods Appraisal Tool. Three reviewers will extract data from the primary studies on the tools or instruments used to elicit women's preferences regarding cervical cancer screening, theoretical frameworks used, outcomes measured, the outstanding themes from quantitative and qualitative evidence, and the identified preferences for cervical cancer screening. We will describe the relationships between study results and the study population, "intervention" (e.g., tool or instrument), and context. We will follow the PRISMA reporting guideline. We will compare findings across studies and between study methods (e.g., qualitative versus quantitative study designs). The strength of the synthesized findings will be assessed using the validated GRADE and CERQual tool. This review will inform the development of a tool to elicit women's cervical screening preferences. Understanding the methods used to elicit women's preferences and what is known about women's cervical screening preferences will be useful for guideline developers who wish to incorporate a woman-centered approach specifically for cervical screening guidelines. PROSPERO CRD42016035737.
An Investigation into the Faculty Development Practices in Chiropractic Education Programs
ERIC Educational Resources Information Center
Scaringe, John G.
2010-01-01
A descriptive case study design using a cross-sectional quantitative survey method was used to investigate the impact of faculty development programs on teaching effectiveness perceived by faculty teaching at chiropractic colleges in the United States. The availability of faculty development programs related to teaching and student learning was…
ERIC Educational Resources Information Center
Yalçin, Sinan; Isgör, Isa Y.
2017-01-01
This study, which investigated the relationship between teachers' professional life qualities and positive psychological capital, was designed in a relational screening pattern in the quantitative research method. Teachers, who worked in primary, secondary and high school in Erzincan city centre of Turkey in 2014-2015 academic year, participated…
A Study of Geometry Content Knowledge of Elementary Preservice Teachers
ERIC Educational Resources Information Center
Aslan-Tutak, Fatma; Adams, Thomasenia Lott
2015-01-01
The purpose of this research is to examine preservice elementary school teachers' geometry learning as investigated by both qualitative and quantitative methods. For the qualitative investigation, narrative analysis and thematic analysis methods were used. The findings of narrative analysis indicated two main kinds of stories: as a learner and as…
ERIC Educational Resources Information Center
Washington, Vanassa
2016-01-01
The overall aim of this quantitative non-experimental study was to investigate the degree to which content-focused professional development, active based-learning professional development and teacher self-efficacy predict student performance in reading, within persistently low-performing schools. The need to investigate professional development in…
ERIC Educational Resources Information Center
Zhang, Jia; Pang, Nicholas Sun-Keung
2016-01-01
This quantitative study investigated and compared the development of professional learning communities in schools located in two Chinese cities, namely, Shanghai and Mianyang. The two cities have significant differences in terms of educational, economic, social, and cultural development. While Shanghai is a directly controlled municipality in East…
Flowers, Sarah A.; Ali, Liaqat; Lane, Catherine S.; Olin, Magnus; Karlsson, Niclas G.
2013-01-01
Rheumatoid arthritis is a common and debilitating systemic inflammatory condition affecting up to 1% of the world's population. This study aimed to investigate the immunological significance of O-glycans in chronic arthritis at a local and systemic level. O-Glycans released from synovial glycoproteins during acute and chronic arthritic conditions were compared and immune-reactive glycans identified. The sulfated core 1 O-glycan (Galβ1–3GalNAcol) was immune reactive, showing a different isomeric profile in the two conditions. From acute reactive arthritis, three isomers could be sequenced, but in patients with chronic rheumatoid arthritis, only a single 3-Gal sulfate-linked isomer could be identified. The systemic significance of this glycan epitope was investigated using the salivary mucin MUC7 in patients with rheumatoid arthritis and normal controls. To analyze this low abundance glycan, a selected reaction monitoring (SRM) method was developed to differentiate and relatively quantitate the core 1 O-glycan and the sulfated core 1 O-glycan Gal- and GalNAc-linked isomers. The acquisition of highly sensitive full scan linear ion trap MS/MS spectra in addition to quantitative SRM data allowed the 3- and 6-linked Gal isomers to be differentiated. The method was used to relatively quantitate the core 1 glycans from MUC7 to identify any systemic changes in this carbohydrate epitope. A statistically significant increase in sulfation was identified in salivary MUC7 from rheumatoid arthritis patients. This suggests a potential role for this epitope in chronic inflammation. This study was able to develop an SRM approach to specifically identify and relatively quantitate sulfated core 1 isomers and the unsulfated structure. The expansion of this method may afford an avenue for the high throughput investigation of O-glycans. PMID:23457413
Student Perceptions of Their Doctoral Programs: Case Study
ERIC Educational Resources Information Center
Moffett, David W.
2015-01-01
The Investigator studied three Doctor of Philosophy program concentrations for a two year period, 2013-2015. The intent of the confidential study was to determine factors affecting program participants' perceptions most. A mixed methods embedded study was applied, with the quantitative portion representing the secondary data source and the…
Literacy, Language and Social Interaction in Special Schools
ERIC Educational Resources Information Center
Reichenberg, Monica
2015-01-01
The present study is a follow up study to a quantitative intervention study where two intervention programs, Reciprocal Teaching and Inference Training, were practiced. This study aims at capturing the potentials benefits and qualitative aspects of one of the programs evaluated, Reciprocal Teaching. More specifically, I have investigated the video…
NASA Astrophysics Data System (ADS)
Wang, Yunzhi; Qiu, Yuchen; Thai, Theresa; More, Kathleen; Ding, Kai; Liu, Hong; Zheng, Bin
2016-03-01
How to rationally identify epithelial ovarian cancer (EOC) patients who will benefit from bevacizumab or other antiangiogenic therapies is a critical issue in EOC treatments. The motivation of this study is to quantitatively measure adiposity features from CT images and investigate the feasibility of predicting potential benefit of EOC patients with or without receiving bevacizumab-based chemotherapy treatment using multivariate statistical models built based on quantitative adiposity image features. A dataset involving CT images from 59 advanced EOC patients were included. Among them, 32 patients received maintenance bevacizumab after primary chemotherapy and the remaining 27 patients did not. We developed a computer-aided detection (CAD) scheme to automatically segment subcutaneous fat areas (VFA) and visceral fat areas (SFA) and then extracted 7 adiposity-related quantitative features. Three multivariate data analysis models (linear regression, logistic regression and Cox proportional hazards regression) were performed respectively to investigate the potential association between the model-generated prediction results and the patients' progression-free survival (PFS) and overall survival (OS). The results show that using all 3 statistical models, a statistically significant association was detected between the model-generated results and both of the two clinical outcomes in the group of patients receiving maintenance bevacizumab (p<0.01), while there were no significant association for both PFS and OS in the group of patients without receiving maintenance bevacizumab. Therefore, this study demonstrated the feasibility of using quantitative adiposity-related CT image features based statistical prediction models to generate a new clinical marker and predict the clinical outcome of EOC patients receiving maintenance bevacizumab-based chemotherapy.
A framework for organizing and selecting quantitative approaches for benefit-harm assessment.
Puhan, Milo A; Singh, Sonal; Weiss, Carlos O; Varadhan, Ravi; Boyd, Cynthia M
2012-11-19
Several quantitative approaches for benefit-harm assessment of health care interventions exist but it is unclear how the approaches differ. Our aim was to review existing quantitative approaches for benefit-harm assessment and to develop an organizing framework that clarifies differences and aids selection of quantitative approaches for a particular benefit-harm assessment. We performed a review of the literature to identify quantitative approaches for benefit-harm assessment. Our team, consisting of clinicians, epidemiologists, and statisticians, discussed the approaches and identified their key characteristics. We developed a framework that helps investigators select quantitative approaches for benefit-harm assessment that are appropriate for a particular decisionmaking context. Our framework for selecting quantitative approaches requires a concise definition of the treatment comparison and population of interest, identification of key benefit and harm outcomes, and determination of the need for a measure that puts all outcomes on a single scale (which we call a benefit and harm comparison metric). We identified 16 quantitative approaches for benefit-harm assessment. These approaches can be categorized into those that consider single or multiple key benefit and harm outcomes, and those that use a benefit-harm comparison metric or not. Most approaches use aggregate data and can be used in the context of single studies or systematic reviews. Although the majority of approaches provides a benefit and harm comparison metric, only four approaches provide measures of uncertainty around the benefit and harm comparison metric (such as a 95 percent confidence interval). None of the approaches considers the actual joint distribution of benefit and harm outcomes, but one approach considers competing risks when calculating profile-specific event rates. Nine approaches explicitly allow incorporating patient preferences. The choice of quantitative approaches depends on the specific question and goal of the benefit-harm assessment as well as on the nature and availability of data. In some situations, investigators may identify only one appropriate approach. In situations where the question and available data justify more than one approach, investigators may want to use multiple approaches and compare the consistency of results. When more evidence on relative advantages of approaches accumulates from such comparisons, it will be possible to make more specific recommendations on the choice of approaches.
A framework for organizing and selecting quantitative approaches for benefit-harm assessment
2012-01-01
Background Several quantitative approaches for benefit-harm assessment of health care interventions exist but it is unclear how the approaches differ. Our aim was to review existing quantitative approaches for benefit-harm assessment and to develop an organizing framework that clarifies differences and aids selection of quantitative approaches for a particular benefit-harm assessment. Methods We performed a review of the literature to identify quantitative approaches for benefit-harm assessment. Our team, consisting of clinicians, epidemiologists, and statisticians, discussed the approaches and identified their key characteristics. We developed a framework that helps investigators select quantitative approaches for benefit-harm assessment that are appropriate for a particular decisionmaking context. Results Our framework for selecting quantitative approaches requires a concise definition of the treatment comparison and population of interest, identification of key benefit and harm outcomes, and determination of the need for a measure that puts all outcomes on a single scale (which we call a benefit and harm comparison metric). We identified 16 quantitative approaches for benefit-harm assessment. These approaches can be categorized into those that consider single or multiple key benefit and harm outcomes, and those that use a benefit-harm comparison metric or not. Most approaches use aggregate data and can be used in the context of single studies or systematic reviews. Although the majority of approaches provides a benefit and harm comparison metric, only four approaches provide measures of uncertainty around the benefit and harm comparison metric (such as a 95 percent confidence interval). None of the approaches considers the actual joint distribution of benefit and harm outcomes, but one approach considers competing risks when calculating profile-specific event rates. Nine approaches explicitly allow incorporating patient preferences. Conclusion The choice of quantitative approaches depends on the specific question and goal of the benefit-harm assessment as well as on the nature and availability of data. In some situations, investigators may identify only one appropriate approach. In situations where the question and available data justify more than one approach, investigators may want to use multiple approaches and compare the consistency of results. When more evidence on relative advantages of approaches accumulates from such comparisons, it will be possible to make more specific recommendations on the choice of approaches. PMID:23163976
21 CFR 1308.31 - Application for exemption of a nonnarcotic prescription product.
Code of Federal Regulations, 2011 CFR
2011-04-01
... the following information: (1) The complete quantitative composition of the dosage form. (2... product including animal investigations and clinical evaluations and studies, with emphasis on the psychic...
Does Lean healthcare improve patient satisfaction? A mixed-method investigation into primary care.
Poksinska, Bozena Bonnie; Fialkowska-Filipek, Malgorzata; Engström, Jon
2017-02-01
Lean healthcare is claimed to contribute to improved patient satisfaction, but there is limited evidence to support this notion. This study investigates how primary-care centres working with Lean define and improve value from the patient's perspective, and how the application of Lean healthcare influences patient satisfaction. This paper contains two qualitative case studies and a quantitative study based on results from the Swedish National Patient Survey. Through the case studies, we investigated how primary-care organisations realised the principle of defining and improving value from the patient's perspective. In the quantitative study, we compared results from the patient satisfaction survey for 23 primary-care centres working with Lean with a control group of 23 care centres not working with Lean. We also analysed changes in patient satisfaction over time. Our case studies reveal that Lean healthcare implementations primarily target efficiency and little attention is paid to the patient's perspective. The quantitative study shows no significantly better results in patient satisfaction for primary-care centres working with Lean healthcare compared with those not working with Lean. Further, care centres working with Lean show no significant improvements in patient satisfaction over time. Lean healthcare implementations seem to have a limited impact on improving patient satisfaction. Care providers need to pay more attention to integrating the patient's perspective in the application of Lean healthcare. Value needs to be defined and value streams need to be improved based on both the knowledge and clinical expertise of care providers, and the preferences and needs of patients. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.
Holzweber, Markus; Lippitz, Andreas; Krueger, Katharina; Jankowski, Joachim; Unger, Wolfgang E. S.
2015-01-01
The surfaces of polymeric dialyzer membranes consisting of polysulfone and poly-vinylpyrrolidone were investigated regarding the lateral distribution and quantitative surface composition using time-of-flight secondary-ion-mass-spectrometry and x-ray photoelectron spectroscopy. Knowledge of the distribution and composition on the outer surface region is of utmost importance for understanding the biocompatibility of such dialyzer membranes. Both flat membranes and hollow fiber membranes were studied. PMID:25711334
DOE Office of Scientific and Technical Information (OSTI.GOV)
Vazehrad, S., E-mail: vazehrad@kth.se; Elfsberg, J., E-mail: jessica.elfsberg@scania.com; Diószegi, A., E-mail: attila.dioszegi@jth.hj.se
An investigation on silicon segregation of lamellar, compacted and nodular graphite iron was carried out by applying a selective, immersion color etching and a modified electron microprobe to study the microstructure. The color etched micrographs of the investigated cast irons by revealing the austenite phase have provided data about the chronology and mechanism of microstructure formation. Moreover, electron microprobe has provided two dimensional segregation maps of silicon. A good agreement was found between the segregation profile of silicon in the color etched microstructure and the silicon maps achieved by electron microprobe analysis. However, quantitative silicon investigation was found to bemore » more accurate than color etching results to study the size of the eutectic colonies. - Highlights: • Sensitivity of a color etchant to silicon segregation is quantitatively demonstrated. • Si segregation measurement by EMPA approved the results achieved by color etching. • Color etched micrographs provided data about solidification mechanism in cast irons. • Austenite grain boundaries were identified by measuring the local Si concentration.« less
Structural, chemical and physical properties of pure and La3+ doped L-Threonine acetate crystals
NASA Astrophysics Data System (ADS)
Senthamizhan, A.; Sambathkumar, K.; Nithiyanantham, S.; Venkatachalapathy, M.; Rajkamal, N.
2017-12-01
The pure and La3+ doped L- Threonine crystals can be grown by slow evaporation techniques. The crystal structure were examined through X-Ray diffraction (XRD) analysis, confirmed the P212121 system. The quantitative nature of dopant can be analyzed with Inductively Coupled Plasma (ICP) study. The Fourier Transform Infra-Red (FTIR) and Fourier Transform (FT- Raman) investigations yields the possible stretching/bonding with their functional groups and the qualitative/quantitative nature of both crystals is analyzed. The optical behavior of crystals can be studied through Ultra Violet (UV) - Visible spectrometer. The mechanical, thermal and decomposition studies can be carried out through Vickers hardness test, Thermo Gravometric Analysis (TGA) and Differential Thermal Analysis (DTA). The Non Linear Optical (NLO) properties are found more than Potassium Phosphate (KDP) through Kurtz powders technique. The dielectric and optical absorption studies for both pure and L-doped crystals were studied and interpreted all the properties. The La3+ dopant increases the properties are investigated.
Mixed methods research - the best of both worlds?
van Griensven, Hubert; Moore, Ann P; Hall, Valerie
2014-10-01
There has been a bias towards quantitative research approaches within manual therapy, which may have resulted in a narrow understanding of manual therapy practice. The aim of this Masterclass is to make a contribution to the expansion of methodologies used in manual therapy enquiry by discussing mixed methods research (MMR), a methodology which utilises both qualitative and quantitative methods within a single study in order to provide more comprehensive insights. To review rationales for MMR, as well as some of the common design options and potential difficulties. The paper also discusses theoretical frameworks that have been used to underpin qualitative and quantitative research, and ongoing debates about the possibility of combining them. Complexities associated with health and manual therapy cannot always be investigated satisfactorily by using a single research method. Some issues require a more comprehensive understanding, which may be provided by combining the strengths of quantitative and qualitative methods in a mixed methods study. Copyright © 2014 Elsevier Ltd. All rights reserved.
Communication Behaviors and Trust in Collaborative Online Teams
ERIC Educational Resources Information Center
Bulu, Saniye Tugba; Yildirim, Zahide
2008-01-01
This study investigates preservice teachers' trust levels and collaborative communication behaviors namely leadership, feedback, social interaction, enthusiasm, task and technical uncertainties, and task-oriented interactions in online learning environment. A case study design involving qualitative and quantitative data collection and analysis was…
NASA Astrophysics Data System (ADS)
Furlong, Cosme; Pryputniewicz, Ryszard J.
1998-05-01
Increased demands on the performance and efficiency of mechanical components impose challenges on their engineering design and optimization, especially when new and more demanding applications must be developed in relatively short periods of time while satisfying design objectives, as well as cost and manufacturability. In addition, reliability and durability must be taken into consideration. As a consequence, effective quantitative methodologies, computational and experimental, should be applied in the study and optimization of mechanical components. Computational investigations enable parametric studies and the determination of critical engineering design conditions, while experimental investigations, especially those using optical techniques, provide qualitative and quantitative information on the actual response of the structure of interest to the applied load and boundary conditions. We discuss a hybrid experimental and computational approach for investigation and optimization of mechanical components. The approach is based on analytical, computational, and experimental resolutions methodologies in the form of computational, noninvasive optical techniques, and fringe prediction analysis tools. Practical application of the hybrid approach is illustrated with representative examples that demonstrate the viability of the approach as an effective engineering tool for analysis and optimization.
Gardner, Tania; Refshauge, Kathryn; Smith, Lorraine; McAuley, James; Hübscher, Markus; Goodall, Stephen
2017-07-01
What influence do physiotherapists' beliefs and attitudes about chronic low back pain have on their clinical management of people with chronic low back pain? Systematic review with data from quantitative and qualitative studies. Quantitative and qualitative studies were included if they investigated an association between physiotherapists' attitudes and beliefs about chronic low back pain and their clinical management of people with chronic low back pain. Five quantitative and five qualitative studies were included. Quantitative studies used measures of treatment orientation and fear avoidance to indicate physiotherapists' beliefs and attitudes about chronic low back pain. Quantitative studies showed that a higher biomedical orientation score (indicating a belief that pain and disability result from a specific structural impairment, and treatment is selected to address that impairment) was associated with: advice to delay return to work, advice to delay return to activity, and a belief that return to work or activity is a threat to the patient. Physiotherapists' fear avoidance scores were positively correlated with: increased certification of sick leave, advice to avoid return to work, and advice to avoid return to normal activity. Qualitative studies revealed two main themes attributed to beliefs and attitudes of physiotherapists who have a relationship to their management of chronic low back pain: treatment orientation and patient factors. Both quantitative and qualitative studies showed a relationship between treatment orientation and clinical practice. The inclusion of qualitative studies captured the influence of patient factors in clinical practice in chronic low back pain. There is a need to recognise that both beliefs and attitudes regarding treatment orientation of physiotherapists, and therapist-patient factors need to be considered when introducing new clinical practice models, so that the adoption of new clinical practice is maximised. [Gardner T, Refshauge K, Smith L, McAuley J, Hübscher M, Goodall S (2017) Physiotherapists' beliefs and attitudes influence clinical practice in chronic low back pain: a systematic review of quantitative and qualitative studies. Journal of Physiotherapy 63: 132-143]. Copyright © 2017 Australian Physiotherapy Association. Published by Elsevier B.V. All rights reserved.
Franzen, Lutz; Anderski, Juliane; Windbergs, Maike
2015-09-01
For rational development and evaluation of dermal drug delivery, the knowledge of rate and extent of substance penetration into the human skin is essential. However, current analytical procedures are destructive, labor intense and lack a defined spatial resolution. In this context, confocal Raman microscopy bares the potential to overcome current limitations in drug depth profiling. Confocal Raman microscopy already proved its suitability for the acquisition of qualitative penetration profiles, but a comprehensive investigation regarding its suitability for quantitative measurements inside the human skin is still missing. In this work, we present a systematic validation study to deploy confocal Raman microscopy for quantitative drug depth profiling in human skin. After we validated our Raman microscopic setup, we successfully established an experimental procedure that allows correlating the Raman signal of a model drug with its controlled concentration in human skin. To overcome current drawbacks in drug depth profiling, we evaluated different modes of peak correlation for quantitative Raman measurements and offer a suitable operating procedure for quantitative drug depth profiling in human skin. In conclusion, we successfully demonstrate the potential of confocal Raman microscopy for quantitative drug depth profiling in human skin as valuable alternative to destructive state-of-the-art techniques. Copyright © 2015 Elsevier B.V. All rights reserved.
Wu, Ed X.; Tang, Haiying; Tong, Christopher; Heymsfield, Steve B.; Vasselli, Joseph R.
2015-01-01
This study aimed to develop a quantitative and in vivo magnetic resonance imaging (MRI) approach to investigate the muscle growth effects of anabolic steroids. A protocol of MRI acquisition on a standard clinical 1.5 Tesla scanner and quantitative image analysis was established and employed to measure the individual muscle and organ volumes in the intact and castrated guinea pigs undergoing a 16-week treatment protocol by two well-documented anabolic steroids, testosterone and nandrolone, via implanted silastic capsules. High correlations between the in vivo MRI and postmortem dissection measurements were observed for shoulder muscle complex (R = 0.86), masseter (R=0.79), temporalis (R=0.95), neck muscle complex (R=0.58), prostate gland and seminal vesicles (R=0.98), and testis (R=0.96). Furthermore, the longitudinal MRI measurements yielded adequate sensitivity to detect the restoration of growth to or towards normal in castrated guinea pigs by replacing circulating steroid levels to physiological or slightly higher levels, as expected. These results demonstrated that quantitative MRI using a standard clinical scanner provides accurate and sensitive measurement of individual muscles and organs, and this in vivo MRI protocol in conjunction with the castrated guinea pig model constitutes an effective platform to investigate the longitudinal and cross-sectional growth effects of other potential anabolic steroids. The quantitative MRI protocol developed can also be readily adapted for human studies on most clinical MRI scanner to investigate the anabolic steroid growth effects, or monitor the changes in individual muscle and organ volume and geometry following injury, strength training, neuromuscular disorders, and pharmacological or surgical interventions. PMID:18241900
Student Attrition in Mathematics E-Learning
ERIC Educational Resources Information Center
Smith, Glenn Gordon; Ferguson, David
2005-01-01
Qualitative studies indicate that mathematics does not work well in e-learning. The current study used quantitative methods to investigate more objectively the extent of problems with mathematics in e-learning. The authors used student attrition as a simple measure of student satisfaction and course viability in two studies, one investigating…
Discussion Based Fish Bowl Strategy in Learning Psychology
ERIC Educational Resources Information Center
Singaravelu, G.
2007-01-01
The present study investigates the learning problems in psychology at Master of Education(M.Ed.,) in Bharathiar University and finds the effectiveness of Discussion Based Fish Bowl Strategy in learning psychology. Single group Experimental method was adopted for the study. Both qualitative and quantitative approaches were adopted for this study.…
Curriculum Orientations and Educational Philosophies of High School Arabic Teachers
ERIC Educational Resources Information Center
Alsalem, Abeer Saleh
2018-01-01
This study aims to investigate the curriculum orientations of High school Arabic teacher in Riyadh city and to examine the relationship between curriculum orientation and their educational philosophies. The quantitative method (descriptive study) was adopted in this questionnaire survey-based study. Mean and standard deviation for the overall of…
Motivation to Read among Rural Adolescents
ERIC Educational Resources Information Center
Belken, Gloria
2013-01-01
This study used quantitative methods to investigate motivation to read among high school students in a tenth-grade English course at a rural high school in the Midwestern USA. Data were collected and analyzed to replicate previous studies. In this study, when compared to large-scale surveys, respondents showed more positive attitudes toward…
Visser, Cobus; Kieser, Eduard; Dellimore, Kiran; van den Heever, Dawie; Smith, Johan
2017-10-01
This study explores the feasibility of prospectively assessing infant dehydration using four non-invasive, optical sensors based on the quantitative and objective measurement of various clinical markers of dehydration. The sensors were investigated to objectively and unobtrusively assess the hydration state of an infant based on the quantification of capillary refill time (CRT), skin recoil time (SRT), skin temperature profile (STP) and skin tissue hydration by means of infrared spectrometry (ISP). To evaluate the performance of the sensors a clinical study was conducted on a cohort of 10 infants (aged 6-36 months) with acute gastroenteritis. High sensitivity and specificity were exhibited by the sensors, in particular the STP and SRT sensors, when combined into a fusion regression model (sensitivity: 0.90, specificity: 0.78). The SRT and STP sensors and the fusion model all outperformed the commonly used "gold standard" clinical dehydration scales including the Gorelick scale (sensitivity: 0.56, specificity: 0.56), CDS scale (sensitivity: 1.0, specificity: 0.2) and WHO scale (sensitivity: 0.13, specificity: 0.79). These results suggest that objective and quantitative assessment of infant dehydration may be possible using the sensors investigated. However, further evaluation of the sensors on a larger sample population is needed before deploying them in a clinical setting. Copyright © 2017 IPEM. Published by Elsevier Ltd. All rights reserved.
Teaching concepts of energy to nigerian children in the 7-11 year-old age range
NASA Astrophysics Data System (ADS)
Urevbu, Andrew O.
This study investigated the level of concept attainment of selected energy concepts for possible inclusion in the Nigerian (Bendel State) Primary Science Project (BPSP). Using an experimental design suggested by Solomon (1949), subjects were taught energy concepts at three levels - descriptive, comparative and quantitative. Results showed that levels of concept comprehension were hierarchical with a signficant decrease in achievement from descriptive to comparative and quantitative concepts. The results of this study suggest the need to describe levels of concept for particular grades in the elementary school curriculum and to match curriculum with thinking strategies of children.
NASA Astrophysics Data System (ADS)
Chiarot, C. B.; Siewerdsen, J. H.; Haycocks, T.; Moseley, D. J.; Jaffray, D. A.
2005-11-01
Development, characterization, and quality assurance of advanced x-ray imaging technologies require phantoms that are quantitative and well suited to such modalities. This note reports on the design, construction, and use of an innovative phantom developed for advanced imaging technologies (e.g., multi-detector CT and the numerous applications of flat-panel detectors in dual-energy imaging, tomosynthesis, and cone-beam CT) in diagnostic and image-guided procedures. The design addresses shortcomings of existing phantoms by incorporating criteria satisfied by no other single phantom: (1) inserts are fully 3D—spherically symmetric rather than cylindrical; (2) modules are quantitative, presenting objects of known size and contrast for quality assurance and image quality investigation; (3) features are incorporated in ideal and semi-realistic (anthropomorphic) contexts; and (4) the phantom allows devices to be inserted and manipulated in an accessible module (right lung). The phantom consists of five primary modules: (1) head, featuring contrast-detail spheres approximate to brain lesions; (2) left lung, featuring contrast-detail spheres approximate to lung modules; (3) right lung, an accessible hull in which devices may be placed and manipulated; (4) liver, featuring conrast-detail spheres approximate to metastases; and (5) abdomen/pelvis, featuring simulated kidneys, colon, rectum, bladder, and prostate. The phantom represents a two-fold evolution in design philosophy—from 2D (cylindrically symmetric) to fully 3D, and from exclusively qualitative or quantitative to a design accommodating quantitative study within an anatomical context. It has proven a valuable tool in investigations throughout our institution, including low-dose CT, dual-energy radiography, and cone-beam CT for image-guided radiation therapy and surgery.
Assessing Psychodynamic Conflict.
Simmonds, Joshua; Constantinides, Prometheas; Perry, J Christopher; Drapeau, Martin; Sheptycki, Amanda R
2015-09-01
Psychodynamic psychotherapies suggest that symptomatic relief is provided, in part, with the resolution of psychic conflicts. Clinical researchers have used innovative methods to investigate such phenomenon. This article aims to review the literature on quantitative psychodynamic conflict rating scales. An electronic search of the literature was conducted to retrieve quantitative observer-rated scales used to assess conflict noting each measure's theoretical model, information source, and training and clinical experience required. Scales were also examined for levels of reliability and validity. Five quantitative observer-rated conflict scales were identified. Reliability varied from poor to excellent with each measure demonstrating good validity. However a small number of studies and limited links to current conflict theory suggest further clinical research is needed.
Quantitative consensus of supervised learners for diffuse lung parenchymal HRCT patterns
NASA Astrophysics Data System (ADS)
Raghunath, Sushravya; Rajagopalan, Srinivasan; Karwoski, Ronald A.; Bartholmai, Brian J.; Robb, Richard A.
2013-03-01
Automated lung parenchymal classification usually relies on supervised learning of expert chosen regions representative of the visually differentiable HRCT patterns specific to different pathologies (eg. emphysema, ground glass, honey combing, reticular and normal). Considering the elusiveness of a single most discriminating similarity measure, a plurality of weak learners can be combined to improve the machine learnability. Though a number of quantitative combination strategies exist, their efficacy is data and domain dependent. In this paper, we investigate multiple (N=12) quantitative consensus approaches to combine the clusters obtained with multiple (n=33) probability density-based similarity measures. Our study shows that hypergraph based meta-clustering and probabilistic clustering provides optimal expert-metric agreement.
ERIC Educational Resources Information Center
Chida, Yoichi; Hamer, Mark
2008-01-01
This meta-analysis included 729 studies from 161 articles investigating how acute stress responsivity (including stress reactivity and recovery of hypothalamic-pituitary-adrenal [HPA] axis, autonomic, and cardiovascular systems) changes with various chronic psychosocial exposures (job stress; general life stress; depression or hopelessness;…
ERIC Educational Resources Information Center
Khan, Uzma Zafar
2012-01-01
The aim of this quantitative study was to investigate elementary principals' beliefs about reformed science teaching and learning, science subject matter knowledge, and how these factors relate to fourth grade students' superior science outcomes. Online survey methodology was used for data collection and included a demographic…
ERIC Educational Resources Information Center
Mutinta, Given; Govender, Kaymarlin; Gow, Jeff; George, Gavin
2013-01-01
University environments are fertile grounds for risky sexual behaviors. This study investigated students' risky sexual practices at the University of KwaZulu-Natal in Durban, South Africa. Data were collected using quantitative and qualitative methods. A total of 1,405 questionnaires were administered, and 80 in-depth interviews and four focus…
A Study Investigating Indian Middle School Students' Ideas of Design and Designers
ERIC Educational Resources Information Center
Ara, Farhat; Chunawala, Sugra; Natarajan, Chitra
2011-01-01
This paper reports on an investigation into middle school students' naive ideas about, and attitudes towards design and designers. The sample for the survey consisted of students from Classes 7 to 9 from a school located in Mumbai. The data were analysed qualitatively and quantitatively to look for trends in students' responses. Results show that…
ERIC Educational Resources Information Center
White, Jacquelyn M.
2011-01-01
The purpose of this quantitative correlational study was to investigate relationships between grade levels, personal factors of teachers, and instructional variety used by 4th-12th grade teachers in Kern County, California. The population under investigation included 2,844 teachers. 235 elementary, middle school/junior high, and secondary teachers…
ERIC Educational Resources Information Center
Tatar, Erdal; Tüysüz, Cengiz; Tosun, Cemal; Ilhan, Nail
2016-01-01
In this study, it was aimed to investigate the factors affecting students' science achievement according to student science teachers. The survey model which is one of the quantitative research methods was used. The sample was consisted of total 606 student science teachers from four state universities in Turkey. The data were obtained by using the…
ERIC Educational Resources Information Center
Chapman, James David
2012-01-01
America's colleges and universities have expanded campus facilities by renovating and increasing square footage. This is in contrast to general construction activity during the same time period. This quantitative study investigates the relationship between university and college campus facility square footage per FTE and university…
Examining Data-Driven Decision Making in Private/Religious Schools
ERIC Educational Resources Information Center
Hanks, Jason Edward
2011-01-01
The purpose of this study was to investigate non-mandated data-driven decision making in private/religious schools. The school culture support of data use, teacher use of data, leader facilitation of using data, and the availability of data were investigated in three schools. A quantitative survey research design was used to explore the research…
ERIC Educational Resources Information Center
Sammet, Rebecca; Dreesmann, Daniel
2017-01-01
Exemplary for social insects, "Temnothorax" ants allow for various hands-on investigations in biology classes. The aim of this study was to provide a quantitative and qualitative analysis of secondary school students' learning achievement after teaching units with ants lasting between one and six weeks. The questionnaires included…
Investigating Factors Related to Virtual Private Network Adoption in Small Businesses
ERIC Educational Resources Information Center
Lederer, Karen
2012-01-01
The purpose of this quantitative study was to investigate six factors that may influence adoption of virtual private network (VPN) technologies in small businesses with fewer than 100 employees. Prior research indicated small businesses employing fewer than 100 workers do not adopt VPN technology at the same rate as larger competitors, and the…
South Dakota Middle School Mathematics Teachers' Perceptions of Teaching Competencies
ERIC Educational Resources Information Center
Bleecker, Heather A.
2017-01-01
This quantitative research study investigates South Dakota middle school (grades 5-8) mathematics teachers' perceptions of teaching competencies including general pedagogical knowledge (GPK) and mathematical pedagogical content knowledge (MPCK). The study also considered how teacher characteristics relate to teacher competencies. The study…
Children's Environmental Concerns: Expressing Ecophobia
ERIC Educational Resources Information Center
Strife, Susan Jean
2012-01-01
While numerous quantitative studies across disciplines have investigated children's knowledge and attitudes about environmental problems, few studies examine children's feelings about environmental problems--and even fewer have focused on the child's point of view. Through 50 in-depth interviews with urban children (ages 10-12) this research aimed…
Kanamori, Hajime; Rutala, William A; Gergen, Maria F; Sickbert-Bennett, Emily E; Weber, David J
2018-05-07
Susceptibility to germicides for carbapenem/colistin-resistant Enterobacteriaceae is poorly described. We investigated the efficacy of multiple germicides against these emerging antibiotic-resistant pathogens using the disc-based quantitative carrier test method that can produce results more similar to those encountered in healthcare settings than a suspension test. Our study results demonstrated that germicides commonly used in healthcare facilities likely will be effective against carbapenem/colistin-resistant Enterobacteriaceae when used appropriately in healthcare facilities. Copyright © 2018 American Society for Microbiology.
A collection of flow visualization techniques used in the Aerodynamic Research Branch
NASA Technical Reports Server (NTRS)
1984-01-01
Theoretical and experimental research on unsteady aerodynamic flows is discussed. Complex flow fields that involve separations, vortex interactions, and transonic flow effects were investigated. Flow visualization techniques are used to obtain a global picture of the flow phenomena before detailed quantitative studies are undertaken. A wide variety of methods are used to visualize fluid flow and a sampling of these methods is presented. It is emphasized that the visualization technique is a thorough quantitative analysis and subsequent physical understanding of these flow fields.
NASA Technical Reports Server (NTRS)
Baily, N. A.
1974-01-01
Research data obtained by the low dose electronic radiography system are reported. Data cover: (1) localization and tracking of Ta screws implanted in the inner wall of the right ventrical of the heart, (2) use of cross hairs to outline inner or outer heart wall contours, (3) quantitative measure of anatomical components which are stationary in size or change size dynamically, and (4) study of dynamic quantitative data from roentenologic or fluoroscopic procedures.
A Study of Health Education and Its Needs for Elementary School Students
ERIC Educational Resources Information Center
Hussain, Irshad; Alamgir, Muhammad Ahmad; Shahzad, Muhammad
2015-01-01
Health Education, particularly in elementary schools, appears to be a neglected area in Pakistan. This study investigated the health education needs of elementary school students. The purpose of the present study is to assess health education needs of elementary school students. The study adopted mix approach of (qualitative and quantitative)…
Genetic basis of adaptation in Arabidopsis thaliana: local adaptation at the seed dormancy QTL DOG1.
Kronholm, Ilkka; Picó, F Xavier; Alonso-Blanco, Carlos; Goudet, Jérôme; de Meaux, Juliette
2012-07-01
Local adaptation provides an opportunity to study the genetic basis of adaptation and investigate the allelic architecture of adaptive genes. We study delay of germination 1 (DOG1), a gene controlling natural variation in seed dormancy in Arabidopsis thaliana and investigate evolution of dormancy in 41 populations distributed in four regions separated by natural barriers. Using F(ST) and Q(ST) comparisons, we compare variation at DOG1 with neutral markers and quantitative variation in seed dormancy. Patterns of genetic differentiation among populations suggest that the gene DOG1 contributes to local adaptation. Although Q(ST) for seed dormancy is not different from F(ST) for neutral markers, a correlation with variation in summer precipitation supports that seed dormancy is adaptive. We characterize dormancy variation in several F(2) -populations and show that a series of functionally distinct alleles segregate at the DOG1 locus. Theoretical models have shown that the number and effect of alleles segregatin at quantitative trait loci (QTL) have important consequences for adaptation. Our results provide support to models postulating a large number of alleles at quantitative trait loci involved in adaptation. © 2012 The Author(s).
Hintersteiner, Ingrid; Himmelsbach, Markus; Buchberger, Wolfgang W
2015-02-01
In recent years, the development of reliable methods for the quantitation of microplastics in different samples, including evaluating the particles' adverse effects in the marine environment, has become a great concern. Because polyolefins are the most prevalent type of polymer in personal-care products containing microplastics, this study presents a novel approach for their quantitation. The method is suitable for aqueous and hydrocarbon-based products, and includes a rapid sample clean-up involving twofold density separation and a subsequent quantitation with high-temperature gel-permeation chromatography. In contrast with previous procedures, both errors caused by weighing after insufficient separation of plastics and matrix and time-consuming visual sorting are avoided. In addition to reliable quantitative results, in this investigation a comprehensive characterization of the polymer particles isolated from the product matrix, covering size, shape, molecular weight distribution and stabilization, is provided. Results for seven different personal-care products are presented. Recoveries of this method were in the range of 92-96 %.
Shukla, Garima; Bhatia, Manvir; Behari, Madhuri
2005-10-01
Small fiber neuropathy is a common neurological disorder, often missed or ignored by physicians, since examination and routine nerve conduction studies are usually normal in this condition. Many methods including quantitative thermal sensory testing are currently being used for early detection of this condition, so as to enable timely investigation and treatment. This study was conducted to assess the yield of quantitative thermal sensory testing in diagnosis of small fiber neuropathy. We included patients presenting with history suggestive of positive and/or negative sensory symptoms, with normal examination findings, clinically suggestive of small fiber neuropathy, with normal or minimally abnormal routine nerve conduction studies. These patients were subjected to quantitative thermal sensory testing using a Medoc TSA-II Neurosensory analyser at two sites and for two modalities. QST data were compared with those in 120 normal healthy controls. Twenty-five patients (16 males, 9 females) with mean age 46.8+/-16.6 years (range: 21-75 years) were included in the study. The mean duration of symptoms was 1.6+/-1.6 years (range: 3 months-6 years). Eighteen patients (72%) had abnormal thresholds in at least one modality. Thermal thresholds were normal in 7 out of the 25 patients. This study demonstrates that quantitative thermal sensory testing is a fairly sensitive method for detection of small fiber neuropathy especially in patients with normal routine nerve conduction studies.
Fears, Scott C.; Service, Susan K.; Kremeyer, Barbara; Araya, Carmen; Araya, Xinia; Bejarano, Julio; Ramirez, Margarita; Castrillón, Gabriel; Gomez-Franco, Juliana; Lopez, Maria C.; Montoya, Gabriel; Montoya, Patricia; Aldana, Ileana; Teshiba, Terri M.; Abaryan, Zvart; Al-Sharif, Noor B.; Ericson, Marissa; Jalbrzikowski, Maria; Luykx, Jurjen J.; Navarro, Linda; Tishler, Todd A.; Altshuler, Lori; Bartzokis, George; Escobar, Javier; Glahn, David C.; Ospina-Duque, Jorge; Risch, Neil; Ruiz-Linares, Andrés; Thompson, Paul M.; Cantor, Rita M.; Lopez-Jaramillo, Carlos; Macaya, Gabriel; Molina, Julio; Reus, Victor I.; Sabatti, Chiara; Freimer, Nelson B.; Bearden, Carrie E.
2014-01-01
IMPORTANCE Genetic factors contribute to risk for bipolar disorder (BP), yet its pathogenesis remains poorly understood. A focus on measuring multi-system quantitative traits that may be components of BP psychopathology may enable genetic dissection of this complex disorder, and investigation of extended pedigrees from genetically isolated populations may facilitate the detection of specific genetic variants that impact on BP as well as its component phenotypes. OBJECTIVE To identify quantitative neurocognitive, temperament-related, and neuroanatomic phenotypes that appear heritable and associated with severe bipolar disorder (BP-I), and therefore suitable for genetic linkage and association studies aimed at identifying variants contributing to BP-I risk. DESIGN Multi-generational pedigree study in two closely related, genetically isolated populations: the Central Valley of Costa Rica (CVCR) and Antioquia, Colombia (ANT). PARTICIPANTS 738 individuals, all from CVCR and ANT pedigrees, of whom 181 are affected with BP-I. MAIN OUTCOME MEASURE Familial aggregation (heritability) and association with BP-I of 169 quantitative neurocognitive, temperament, magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI) phenotypes. RESULTS Seventy-five percent (126) of the phenotypes investigated were significantly heritable, and 31% (53) were associated with BP-I. About 1/4 of the phenotypes, including measures from each phenotype domain, were both heritable and associated with BP-I. Neuroimaging phenotypes, particularly cortical thickness in prefrontal and temporal regions, and volume and microstructural integrity of the corpus callosum, represented the most promising candidate traits for genetic mapping related to BP based on strong heritability and association with disease. Analyses of phenotypic and genetic covariation identified substantial correlations among the traits, at least some of which share a common underlying genetic architecture. CONCLUSIONS AND RELEVANCE This is the most extensive investigation of BP-relevant component phenotypes to date. Our results identify brain and behavioral quantitative traits that appear to be genetically influenced and show a pattern of BP-I-association within families that is consistent with expectations from case-control studies. Together these phenotypes provide a basis for identifying loci contributing to BP-I risk and for genetic dissection of the disorder. PMID:24522887
Exposure assessment of tetrafluoroethylene and ammonium perfluorooctanoate 1951-2002.
Sleeuwenhoek, Anne; Cherrie, John W
2012-03-01
To develop a method to reconstruct exposure to tetrafluoroethylene (TFE) and ammonium perfluorooctanoate (APFO) in plants producing polytetrafluoroethylene (PTFE) in the absence of suitable objective measurements. These data were used to inform an epidemiological study being carried out to investigate possible risks in workers employed in the manufacture of PTFE and to study trends in exposure over time. For each plant, detailed descriptions of all occupational titles, including tasks and changes over time, were obtained during semi-structured interviews with key plant personnel. A semi-quantitative assessment method was used to assess inhalation exposure to TFE and inhalation plus dermal exposure to APFO. Temporal trends in exposure to TFE and APFO were investigated. In each plant the highest exposures for both TFE and APFO occurred in the polymerisation area. Due to the introduction of control measures, increasing process automation and other improvements, exposures generally decreased over time. In the polymerisation area, the annual decline in exposure to TFE varied by plant from 3.8 to 5.7% and for APFO from 2.2 to 5.5%. A simple method for assessing exposure was developed which used detailed process information and job descriptions to estimate average annual TFE and APFO exposure on an arbitrary semi-quantitative scale. These semi-quantitative estimates are sufficient to identify relative differences in exposure for the epidemiological study and should good data become available, they could be used to provide quantitative estimates for all plants across the whole period of operation. This journal is © The Royal Society of Chemistry 2012
ERIC Educational Resources Information Center
Flomo, John S., Jr.
2013-01-01
This study investigated the congruence between higher education and the labor market from the perspectives of college graduates in Liberia. It specifically examined the alignment of the skills college students acquire in college to Liberia's labor market. The study employed a Tracer Study quantitative research methodology. Tracer study as a…
Pre-Service Teachers' Perception toward Environmental Knowledge, Attitudes and Behaviours
ERIC Educational Resources Information Center
Borhan, Mohamad Termizi; Ismail, Zurida
2011-01-01
Purpose: The study investigated the environmental knowledge, attitudes and behaviours exhibited by the pre-service teachers and determined if there was any significant relationship between environmental knowledge, attitudes and behaviours. Method: This descriptive study adopted a quantitative approach using questionnaires to obtain information on…
Comments on "Understanding Graduate Women's Reentry Experiences." Commentary.
ERIC Educational Resources Information Center
Lott, Bernice
1999-01-01
The case-study method used in "Understanding Graduate Women's Reentry Experiences" yielded personal information of considerable depth, but the conclusions drawn from the study are not all that different from those drawn from more quantitative investigations. Suggests that a multimethod approach is the best research strategy. (SLD)
Phenomenographic Study of Students' Problem Solving Approaches in Physics
ERIC Educational Resources Information Center
Walsh, Laura N.; Howard, Robert G.; Bowe, Brian
2007-01-01
This paper describes ongoing research investigating student approaches to quantitative and qualitative problem solving in physics. This empirical study was conducted using a phenomenographic approach to analyze data from individual semistructured problem solving interviews with 22 introductory college physics students. The main result of the study…
Differences in Student Reasoning about Belief-Relevant Arguments: A Mixed Methods Study
ERIC Educational Resources Information Center
McCrudden, Matthew T.; Barnes, Ashleigh
2016-01-01
This mixed methods study investigated high school students' evaluations of scientific arguments. Myside bias occurs when individuals evaluate belief-consistent information more favorably than belief-inconsistent information. In the quantitative phase, participants (n = 72 males) rated belief-consistent arguments more favorably than…
Student-Athlete Wellbeing and Persistence: An In-Depth Look at Student-Athlete Perceptions
ERIC Educational Resources Information Center
Kamusoko, Sibongile D.; Pemberton, Cynthia Lee A.
2012-01-01
This study investigated student-athlete perceptions of wellbeing, delimited to satisfaction regarding Athletic Department Policies and Practices, Educational Characteristics, Institutional Facilities and Services, and intent to academically persist. The study employed quantitative and qualitative data queries. This paper reports emergent findings…
Interrelations between siblings and parents in families living with children with cancer.
Kobayashi, Kyoko; Hayakawa, Akira; Hohashi, Naohiro
2015-02-01
Having a child diagnosed with cancer is a stressful event for the family. This exploratory multimethod study utilized both quantitative and qualitative multiinformant methodologies to investigate the relationships between parental family functioning and siblings' health-related quality of life (HRQOL) and to describe interrelations between the experiences of parents and siblings of children with childhood cancer. A total of 14 Japanese families participated in the quantitative study, and 4 families of the 14 participated in the qualitative study. In-depth, semistructured interviews revealed three family-unit stages during the time course of the ill child's treatment that included particular parent-sibling interrelations. We also found strong correlation between parental family functioning and siblings' HRQOL in the quantitative study. The results suggest the importance of family nursing interventions directed to individual family members and the family unit that focus on strengthening the parent-sibling relationship and supporting families who are experiencing childhood cancer. © The Author(s) 2014.
Keizer, D; van Wijhe, M; Post, W J; Uges, D R A; Wierda, J M K H
2007-08-01
Allodynia is a common and disabling symptom in many patients with neuropathic pain. Whereas quantification of pain mostly depends on subjective pain reports, allodynia can also be measured objectively with quantitative sensory testing. In this pilot study, we investigated the clinical relevance of quantitative sensory testing with Von Frey monofilaments in patients with allodynia as a consequence of a neuropathic pain syndrome, by means of correlating subjective pain scores with pain thresholds obtained with quantitative sensory testing. During a 4-week trial, we administered a cannabis extract to 17 patients with allodynia. We quantified the severity of the allodynia with Von Frey monofilaments before, during and after the patients finished the trial. We also asked the patients to rate their pain on a numeric rating scale at these three moments. We found that most of the effect of the cannabis occurred in the last 2 weeks of the trial. In this phase, we observed that the pain thresholds, as measured with Von Frey monofilaments, were inversely correlated with a decrease of the perceived pain intensity. These preliminary findings indicate clinical relevance of quantitative sensory testing with Von Frey monofilaments in the quantification of allodynia in patients with neuropathic pain, although confirmation of our data is still required in further studies to position this method of quantitative sensory testing as a valuable tool, for example, in the evaluation of therapeutic interventions for neuropathic pain.
Investigation of the Thermomechanical Response of Shape Memory Alloy Hybrid Composite Beams
NASA Technical Reports Server (NTRS)
Davis, Brian A.
2005-01-01
Previous work at NASA Langley Research Center (LaRC) involved fabrication and testing of composite beams with embedded, pre-strained shape memory alloy (SMA) ribbons. That study also provided comparison of experimental results with numerical predictions from a research code making use of a new thermoelastic model for shape memory alloy hybrid composite (SMAHC) structures. The previous work showed qualitative validation of the numerical model. However, deficiencies in the experimental-numerical correlation were noted and hypotheses for the discrepancies were given for further investigation. The goal of this work is to refine the experimental measurement and numerical modeling approaches in order to better understand the discrepancies, improve the correlation between prediction and measurement, and provide rigorous quantitative validation of the numerical model. Thermal buckling, post-buckling, and random responses to thermal and inertial (base acceleration) loads are studied. Excellent agreement is achieved between the predicted and measured results, thereby quantitatively validating the numerical tool.
Jaferzadeh, Keyvan; Moon, Inkyu
2015-11-01
Quantitative phase information obtained by digital holographic microscopy (DHM) can provide new insight into the functions and morphology of single red blood cells (RBCs). Since the functionality of a RBC is related to its three-dimensional (3-D) shape, quantitative 3-D geometric changes induced by storage time can help hematologists realize its optimal functionality period. We quantitatively investigate RBC 3-D geometric changes in the storage lesion using DHM. Our experimental results show that the substantial geometric transformation of the biconcave-shaped RBCs to the spherocyte occurs due to RBC storage lesion. This transformation leads to progressive loss of cell surface area, surface-to-volume ratio, and functionality of RBCs. Furthermore, our quantitative analysis shows that there are significant correlations between chemical and morphological properties of RBCs.
Global-Mindedness and Intercultural Competence: A Quantitative Study of Pre-Service Teachers
ERIC Educational Resources Information Center
Cui, Qi
2013-01-01
This study assessed pre-service teachers' levels of global-mindedness and intercultural competence using the Global-Mindedness Scale (GMS) and the Cultural Intelligence Scale (CQS) and investigated the correlation between the two. The study examined whether the individual scale factors such as gender, perceived competence in non-native language or…
ERIC Educational Resources Information Center
Harcarik, Michele
2009-01-01
This mixed methods study investigates the relationship between fifth-grade teachers' social studies knowledge and beliefs and their relationship to classroom practices. Quantitative data were collected through a beliefs and classroom practices survey and 60-item knowledge test covering the areas of American History, America and the World,…
ERIC Educational Resources Information Center
Li, Winnie Sim Siew; Arshad, Mohammad Yusof
2015-01-01
Purpose: Inquiry teaching has been suggested as one of the important approaches in teaching chemistry. This study investigates the inquiry practices among chemistry teachers. Method: A combination of quantitative and qualitative study was applied in this study to provide detailed information about inquiry teaching practices. Questionnaires,…
ERIC Educational Resources Information Center
Llego, Jordan Hso
2017-01-01
This study investigated the Emotional Intelligence (EI) of Science, Technology and Engineering (STE) science teachers based on their demographic profile. Total enumeration was used and 113 STE science teachers in Region 1 Philippines participated in this study. The study adopted descriptive- quantitative research design, frequency count and…
ERIC Educational Resources Information Center
Wilkens, Eric S.
2013-01-01
This quantitative study attempted to understand the factors that influence Minnesota community and technical college students to pursue Information Technology (IT) certification. The study investigated the problem of determining the factors that influence Minnesota community and technical college students to pursue IT certification along with…
Outcomes of Orphanhood in Ethiopia: A Mixed Methods Study
ERIC Educational Resources Information Center
Camfield, Laura
2011-01-01
The paper addresses the question of whether parental death always has a strongly negative effect on children's outcomes using quantitative and qualitative data from Young Lives, a longitudinal study of childhood poverty in Ethiopia. It investigates the validity of potential mediating factors identified by other studies in Sub-Saharan Africa using…
Observational Learning among Older Adults Living in Nursing Homes
ERIC Educational Resources Information Center
Story, Colleen D.
2010-01-01
The purpose of this study was to evaluate learning by older adults living in nursing homes through observational learning based on Bandura's (1977) social learning theory. This quantitative study investigated if older adults could learn through observation. The nursing homes in the study were located in the midwestern United States. The…
Supporting Social Studies Reading Comprehension with an Electronic Pop-Up Dictionary
ERIC Educational Resources Information Center
Fry, Sara Winstead; Gosky, Ross
2008-01-01
This study investigated how middle school students' comprehension was impacted by reading social studies texts online with a pop-up dictionary function for every word in the text. A quantitative counterbalance design was used to determine how 129 middle school students' reading comprehension test scores for the pop-up dictionary reading differed…
van Zadelhoff, Claudia; Ehrle, Anna; Merle, Roswitha; Jahn, Werner; Lischer, Christoph
2018-05-09
Scintigraphy is a standard diagnostic method for evaluating horses with back pain due to suspected thoracic processus spinosus pathology. Lesion detection is based on subjective or semi-quantitative assessments of increased uptake. This retrospective, analytical study is aimed to compare semi-quantitative and subjective methods in the evaluation of scintigraphic images of the processi spinosi in the equine thoracic spine. Scintigraphic images of 20 Warmblood horses, presented for assessment of orthopedic conditions between 2014 and 2016, were included in the study. Randomized, blinded image evaluation was performed by 11 veterinarians using subjective and semi-quantitative methods. Subjective grading was performed for the analysis of red-green-blue and grayscale scintigraphic images, which were presented in full-size or as masked images. For the semi-quantitative assessment, observers placed regions of interest over each processus spinosus. The uptake ratio of each processus spinosus in comparison to a reference region of interest was determined. Subsequently, a modified semi-quantitative calculation was developed whereby only the highest counts-per-pixel for a specified number of pixels was processed. Inter- and intraobserver agreement was calculated using intraclass correlation coefficients. Inter- and intraobserver intraclass correlation coefficients were 41.65% and 71.39%, respectively, for the subjective image assessment. Additionally, a correlation between intraobserver agreement, experience, and grayscale images was identified. The inter- and intraobserver agreement was significantly increased when using semi-quantitative analysis (97.35% and 98.36%, respectively) or the modified semi-quantitative calculation (98.61% and 98.82%, respectively). The proposed modified semi-quantitative technique showed a higher inter- and intraobserver agreement when compared to other methods, which makes it a useful tool for the analysis of scintigraphic images. The association of the findings from this study with clinical and radiological examinations requires further investigation. © 2018 American College of Veterinary Radiology.
Standardized observation of neighbourhood disorder: does it work in Canada?
2010-01-01
Background There is a growing body of evidence that where you live is important to your health. Despite numerous previous studies investigating the relationship between neighbourhood deprivation (and structure) and residents' health, the precise nature of this relationship remains unclear. Relatively few investigations have relied on direct observation of neighbourhoods, while those that have were developed primarily in US settings. Evaluation of the transferability of such tools to other contexts is an important first step before applying such instruments to the investigation of health and well-being. This study evaluated the performance of a systematic social observational (SSO) tool (adapted from previous studies of American and British neighbourhoods) in a Canadian urban context. Methods This was a mixed-methods study. Quantitative SSO ratings and qualitative descriptions of 176 block faces were obtained in six Toronto neighbourhoods (4 low-income, and 2 middle/high-income) by trained raters. Exploratory factor analysis was conducted with the quantitative SSO ratings. Content analysis consisted of independent coding of qualitative data by three members of the research team to yield common themes and categories. Results Factor analysis identified three factors (physical decay/disorder, social accessibility, recreational opportunities), but only 'physical decay/disorder' reflected previous findings in the literature. Qualitative results (based on raters' fieldwork experiences) revealed the tool's shortcomings in capturing important features of the neighbourhoods under study, and informed interpretation of the quantitative findings. Conclusions This study tested the performance of an SSO tool in a Canadian context, which is an important initial step before applying it to the study of health and disease. The tool demonstrated important shortcomings when applied to six diverse Toronto neighbourhoods. The study's analyses challenge previously held assumptions (e.g. social 'disorder') regarding neighbourhood social and built environments. For example, neighbourhood 'order' has traditionally been assumed to be synonymous with a certain degree of homogeneity, however the neighbourhoods under study were characterized by high degrees of heterogeneity and low levels of disorder. Heterogeneity was seen as an appealing feature of a block face. Employing qualitative techniques with SSO represents a unique contribution, enhancing both our understanding of the quantitative ratings obtained and of neighbourhood characteristics that are not currently captured by such instruments. PMID:20146821
ERIC Educational Resources Information Center
Marshall, Althea T.
2010-01-01
Purpose: The purpose of this investigation was to examine the impact of Chromosome 4p- syndrome on the communication and expressive language phenotype of a large cross-cultural population of children, adolescents, and adults. Method: A large-scale survey study was conducted and a descriptive research design was used to analyze quantitative and…
ERIC Educational Resources Information Center
de la Fuente, Maria J.
2006-01-01
Framed under a cognitive approach to task-based L2 learning, this study used a pedagogical approach to investigate the effects of three vocabulary lessons (one traditional and two task-based) on acquisition of basic meanings, forms and morphological aspects of Spanish words. Quantitative analysis performed on the data suggests that the type of…
Investigation of a Leadership Development Program.
1998-08-04
by leadership training. A quantitative approach was taken, using Sashkin’s Visionary Leadership Theory (VLT) to study the effects of a certificated... Theory , research, and managerial application. New York: Free Press. Bass, B. M. (1996). A new paradigm of leadership : An inquiry into...factor theory of leadership . Administrative Science Quarterly, 11, 238-263. Investigation of a Leadership Development Program Boyd, J. T., Jr. (1988
ERIC Educational Resources Information Center
Piamsai, Chatraporn
2014-01-01
This study was an attempt to investigate how proficient and non-proficient learners used listening strategies to complete a listening task. 65 third-year Chulalongkorn University Commerce and Accountancy students participated in the first stage of the quantitative data collection. 18 students were randomly selected from the group for more in depth…
Investigating Demotivation in Learning English: An Extension to Sakai and Kikuchi's (2009) Framework
ERIC Educational Resources Information Center
Krishnan, K. Sarojani Devi; Aziz, Jalan Raja Muda Abdul; Pathan, Zahid Hussain
2013-01-01
The aim of this research is to investigate the factors of demotivation in L2 learning of Pakistani undergraduates at the University of Balochistan, Quetta. A mixed-methods research design was employed in this study to explore the factors of demotivation. Quantitative data was obtained from the responses of a population of 116 first semester…
A Study on Using Hands-On Science Inquiries to Promote the Geology Learning of Preservice Teachers
ERIC Educational Resources Information Center
Lai, Ching-San
2015-01-01
This study aims to investigate the geology learning performance of preservice teachers. A total of 31 sophomores (including 11 preservice teachers) from an educational university in Taiwan participated in this study. The course arrangements include class teaching and hands-on science inquiry activities. The study searches both quantitative and…
ERIC Educational Resources Information Center
Akpinar, Kadriye Dilek; Ünaldi, Ihsan
2014-01-01
This study investigated the intercultural outcomes of short-term study visit programs for Foreign Language and Science teacher trainers. A mixed method including quantitative and qualitative data was used to compare the differences between the two groups' intercultural development in terms of their study field. Fantini's questionnaire was used for…
Curtis, Tyler E; Roeder, Ryan K
2017-10-01
Advances in photon-counting detectors have enabled quantitative material decomposition using multi-energy or spectral computed tomography (CT). Supervised methods for material decomposition utilize an estimated attenuation for each material of interest at each photon energy level, which must be calibrated based upon calculated or measured values for known compositions. Measurements using a calibration phantom can advantageously account for system-specific noise, but the effect of calibration methods on the material basis matrix and subsequent quantitative material decomposition has not been experimentally investigated. Therefore, the objective of this study was to investigate the influence of the range and number of contrast agent concentrations within a modular calibration phantom on the accuracy of quantitative material decomposition in the image domain. Gadolinium was chosen as a model contrast agent in imaging phantoms, which also contained bone tissue and water as negative controls. The maximum gadolinium concentration (30, 60, and 90 mM) and total number of concentrations (2, 4, and 7) were independently varied to systematically investigate effects of the material basis matrix and scaling factor calibration on the quantitative (root mean squared error, RMSE) and spatial (sensitivity and specificity) accuracy of material decomposition. Images of calibration and sample phantoms were acquired using a commercially available photon-counting spectral micro-CT system with five energy bins selected to normalize photon counts and leverage the contrast agent k-edge. Material decomposition of gadolinium, calcium, and water was performed for each calibration method using a maximum a posteriori estimator. Both the quantitative and spatial accuracy of material decomposition were most improved by using an increased maximum gadolinium concentration (range) in the basis matrix calibration; the effects of using a greater number of concentrations were relatively small in magnitude by comparison. The material basis matrix calibration was more sensitive to changes in the calibration methods than the scaling factor calibration. The material basis matrix calibration significantly influenced both the quantitative and spatial accuracy of material decomposition, while the scaling factor calibration influenced quantitative but not spatial accuracy. Importantly, the median RMSE of material decomposition was as low as ~1.5 mM (~0.24 mg/mL gadolinium), which was similar in magnitude to that measured by optical spectroscopy on the same samples. The accuracy of quantitative material decomposition in photon-counting spectral CT was significantly influenced by calibration methods which must therefore be carefully considered for the intended diagnostic imaging application. © 2017 American Association of Physicists in Medicine.
Glosses, Comprehension, and Strategy Use
ERIC Educational Resources Information Center
Ko, Myong Hee
2005-01-01
This study, using both qualitative and quantitative measures, investigates how different types of gloss conditions affect Korean college students' reading comprehension. One hundred and six undergraduates at a university in Korea participated in the study. Twelve were assigned to think aloud, and the rest (ninety-four) took part in the main study…
ERIC Educational Resources Information Center
Anderson, Chris James
2016-01-01
A quantitative study with a correlational design, this research investigated whether certified teachers' ratings of their school leader's demonstrated emotional intelligence behaviors correlated with the teacher's perceptions of school climate. A sample of 42 graduate and post baccalaureate students from a Mid-Atlantic region college accessed a…
The Impact of Mentoring on Alternatively Certified Teachers
ERIC Educational Resources Information Center
Kesler, Becky
2013-01-01
The purpose of this study was to explore the perceived effectiveness of mentoring for teachers certified through non-traditional avenues. This quantitative study investigated the type and amount of support teachers certified through the Arkansas Non-traditional Licensure Program (NTLP) and the Master of Arts in Teaching Program (MATP) received…
Academic Administrator Influence on Institutional Commitment to Open Access of Scholarly Research
ERIC Educational Resources Information Center
Reinsfelder, Thomas L.
2012-01-01
This quantitative study investigated the interrelationships among faculty researchers, publishers, librarians, and academic administrators when dealing with the open access of scholarly research. This study sought to identify the nature of any relationship between the perceived attitudes and actions of academic administrators and an…
Teaching and Learning Moral Values through Kindergarten Curriculum
ERIC Educational Resources Information Center
Al-Hooli, Abeer; Al-Shammari, Zaid
2009-01-01
In this research study we investigated kindergarten-aged children's moral values in Kuwait. This study utilized several quantitative and qualitative research methods in the course of looking at three terms--moral development, the meaning of value, and the meaning of morality--as experienced by kindergarten-aged children. Participants were 600…
Chinese Middle School Teachers' Preferences Regarding Performance Evaluation Measures
ERIC Educational Resources Information Center
Liu, Shujie; Xu, Xianxuan; Stronge, James H.
2016-01-01
Teacher performance evaluation currently is receiving unprecedented attention from policy makers, scholars, and practitioners worldwide. This study is one of the few studies of teacher perceptions regarding teacher performance measures that focus on China. We employed a quantitative dominant mixed research design to investigate Chinese teachers'…
Informal Adoption Among Black Families.
ERIC Educational Resources Information Center
Hill, Robert B.
This study of informal adoption patterns among black families throughout the United States examines the role of the extended family and the functioning of a kinship network which includes foster care of children by relatives other than parents. The study's basic mode of investigation was secondary analysis of existing data: quantitative national…
Animation-Based Learning in Geology: Impact of Animations Coupled with Seductive Details
ERIC Educational Resources Information Center
Clayton, Rodney L.
2016-01-01
Research is not clear on how to address the difficulty students have conceptualizing geologic processes and phenomena. This study investigated how animations coupled with seductive details effect learners' situational interest and emotions. A quantitative quasi-experimental study employing an independent-measures factorial design was used. The…
Investigating the Effect of Situational Awareness on Persistence of Doctoral Distance Learners
ERIC Educational Resources Information Center
Harleman, Thomas G.
2013-01-01
This quantitative study sought to identify the effect of heightened situational awareness (SA) on persistence of doctoral distance learners. Factors in the distance learners' micro-environment, vis-à-vis Urie Bronfenbrenner's (1979) ecology theory of human development, were the focus. Study participants included new doctoral candidates continuing…
Negative Particles and Morphemes in Jordanian Arabic Dialects
ERIC Educational Resources Information Center
Mrayat, Ahmad
2015-01-01
This paper aims at investigating the negative particles and morphemes in three main Jordanian dialects (Urban, Rural and Bedouin). This quantitative and qualitative study includes 30 teachers from different disciplines who use these dialects. The sample of the study was selected randomly. The research used two research instruments, a checklist and…
A Quantitative and Qualitative Study of Math Anxiety among Preservice Teachers
ERIC Educational Resources Information Center
Sloan, Tina Rye
2010-01-01
This project investigated the effects of a standards-based mathematics methods course on the mathematics anxiety levels of preservice teachers. The qualitative portion of the study examined aspects of a math methods course that affected mathematics anxiety levels and the antecedents of mathematics anxiety. Findings revealed a significant…
ERIC Educational Resources Information Center
Luckanavanich, Suwannee
2011-01-01
The purpose of this study was to investigate the relationship among lifestyles, personal relationship (friendship and romantic relationship), and living behaviors shared with closed friends and romantic friends. The study undertook a quantitative research of university students' living behaviors in the private residence. A survey questionnaire was…
A Study of "Career Pathways" Policy with Implications for School Leaders
ERIC Educational Resources Information Center
Ormsmith, Michael I.; Mansfield, Katherine Cumings
2014-01-01
This explanatory mixed-methods study began with a quantitative survey to investigate counselor beliefs and implementation behaviors related to providing college and career planning services to high school students. Survey results informed the development and implementation of interview protocol designed to provide deeper insight into counselors'…
Espousing Democratic Leadership Practices: A Study of Values in Action
ERIC Educational Resources Information Center
Devereaux, Lorraine
2003-01-01
This article examines principals' espoused values and their values in action. It provides a reanalysis of previously collected data through a values lens. The original research study was an international quantitative and qualitative investigation of principals' leadership approaches that was based in 15 schools. This particular excerpt of the…
Gender Compatibility, Math-Gender Stereotypes, and Self-Concepts in Math and Physics
ERIC Educational Resources Information Center
Koul, Ravinder; Lerdpornkulrat, Thanita; Poondej, Chanut
2016-01-01
Positive self-assessment of ability in the quantitative domains is considered critical for student participation in science, technology, engineering, and mathematics field studies. The present study investigated associations of gender compatibility (gender typicality and contentedness) and math-gender stereotypes with self-concepts in math and…
Transformative Learning in Managerial Role Transitions
ERIC Educational Resources Information Center
Isopahkala-Bouret, Ulpukka
2008-01-01
The purpose of this study is to investigate the nature of learning in work role transitions from specialist roles to managerial roles in a context of a large international technology organisation. Prior theorisation of learning in role transitions has been based on quantitative, psychologically-oriented studies prescribing different role and…
German Schools Abroad: Hotspots of Elite Multilingualism?
ERIC Educational Resources Information Center
Sander, Anne E; Admiraal, Wilfried
2016-01-01
While multilingualism itself is a widely analyzed topic, a study about multilingualism at German schools abroad is so far unique. This quantitative study investigates the differences in the size of German expressive and receptive vocabulary between monolingual and multilingual students, aged between 5 and 11 years. A cohort of 65 multilingual…
English-Medium Instruction and Intercultural Sensitivity: A Korean Case Study
ERIC Educational Resources Information Center
Kim, Jeongyeon; Choi, Jinsook; Tatar, Bradley
2017-01-01
This case study examined the reactions of local students to the diversity in student population. Specifically, it investigated how the local students' intercultural sensitivity to the international students is interrelated with their perception of the English-medium instruction (EMI) policy. The quantitative and qualitative analyses of the…
Northeast Tennessee Educators' Perception of STEM Education Implementation
ERIC Educational Resources Information Center
Turner, Kristin Beard
2013-01-01
A quantitative nonexperimental survey study was developed to investigate Northeast Tennessee K-8 educators' perceptions of STEM education. This study was an examination of current perceptions of STEM education. Perceived need, current implementation practices, access to STEM resources, definition of STEM, and the current condition of STEM in…
An Investigation into Teacher Turnover in International Schools
ERIC Educational Resources Information Center
Odland, Glenn; Ruzicka, Mary
2009-01-01
This study explored expatriate teacher turnover in international schools. Two hundred and eighty-one international teachers completed a questionnaire identifying which variables influenced their decision to leave at the end of their first contract. Using both quantitative and qualitative data, this study revealed that three causal factors were…
A Correlational Study on Transformational Leadership and Resilience in Higher Education Leadership
ERIC Educational Resources Information Center
Wasden, Shane T.
2014-01-01
This quantitative correlational study investigated the relationship between self-perceived transformational leadership and self-perceived resilience within the confines of higher education leadership. This dissertation is written from a professional practice doctorate (PPD) perspective. A discussion of the PPD and its components is provided along…
Students' Views on Contextual Vocabulary Teaching: A Constructivist View
ERIC Educational Resources Information Center
Tosun, Bahadir Cahit
2016-01-01
The current study is a quantitative research that aims to throw light on the place of students' views on contextual vocabulary teaching in conformity with Constructivism (CVTC) in the field of foreign language teaching. Hence, the study investigates whether any significant correlation exists between the fourth year university students' attitudes…
Technology and Math: An Investigation into Technology and Assessment
ERIC Educational Resources Information Center
Duke, Rebecca Turpin
2015-01-01
The quantitative correlational study evaluates and identifies patterns of teacher use of technology in instruction. The study involved evaluating the scores on the South Carolina End-of-Course (EOC) Algebra 1 test to explore trends and relationships between teachers' reported technology use and student achievement. Educators may be interested in…
Grammatical Errors Produced by English Majors: The Translation Task
ERIC Educational Resources Information Center
Mohaghegh, Hamid; Zarandi, Fatemeh Mahmoudi; Shariati, Mohammad
2011-01-01
This study investigated the frequency of the grammatical errors related to the four categories of preposition, relative pronoun, article, and tense using the translation task. In addition, the frequencies of these grammatical errors in different categories and in each category were examined. The quantitative component of the study further looked…
Internship Experiences for Aspiring Principals: Student Perceptions and Effectiveness
ERIC Educational Resources Information Center
Christian, Ginger R.
2011-01-01
The purpose of this quantitative study was to investigate East Tennessee State University graduate student perceptions on the effectiveness of internship experiences as students explored the implementation of ISLLC Standards and the role of mentor support as they prepared for the principalship. The participating university for this study is…
Lash, Ayhan Aytekin; Plonczynski, Donna J; Sehdev, Amikar
2011-01-01
To compare the inclusion and the influences of selected variables on hypothesis testing during the 1980s and 1990s. In spite of the emphasis on conducting inquiry consistent with the tenets of logical positivism, there have been no studies investigating the frequency and patterns of hypothesis testing in nursing research The sample was obtained from the journal Nursing Research which was the research journal with the highest circulation during the study period under study. All quantitative studies published during the two decades including briefs and historical studies were included in the analyses A retrospective design was used to select the sample. Five years from the 1980s and 1990s each were randomly selected from the journal, Nursing Research. Of the 582 studies, 517 met inclusion criteria. Findings suggest that there has been a decline in the use of hypothesis testing in the last decades of the 20th century. Further research is needed to identify the factors that influence the conduction of research with hypothesis testing. Hypothesis testing in nursing research showed a steady decline from the 1980s to 1990s. Research purposes of explanation, and prediction/ control increased the likelihood of hypothesis testing. Hypothesis testing strengthens the quality of the quantitative studies, increases the generality of findings and provides dependable knowledge. This is particularly true for quantitative studies that aim to explore, explain and predict/control phenomena and/or test theories. The findings also have implications for doctoral programmes, research preparation of nurse-investigators, and theory testing.
Dissection and Downstream Analysis of Zebra Finch Embryos at Early Stages of Development
Murray, Jessica R.; Stanciauskas, Monika E.; Aralere, Tejas S.; Saha, Margaret S.
2014-01-01
The zebra finch (Taeniopygiaguttata) has become an increasingly important model organism in many areas of research including toxicology1,2, behavior3, and memory and learning4,5,6. As the only songbird with a sequenced genome, the zebra finch has great potential for use in developmental studies; however, the early stages of zebra finch development have not been well studied. Lack of research in zebra finch development can be attributed to the difficulty of dissecting the small egg and embryo. The following dissection method minimizes embryonic tissue damage, which allows for investigation of morphology and gene expression at all stages of embryonic development. This permits both bright field and fluorescence quality imaging of embryos, use in molecular procedures such as in situ hybridization (ISH), cell proliferation assays, and RNA extraction for quantitative assays such as quantitative real-time PCR (qtRT-PCR). This technique allows investigators to study early stages of development that were previously difficult to access. PMID:24999108
Investigating the strategic antecedents of agility in humanitarian logistics.
L'Hermitte, Cécile; Brooks, Benjamin; Bowles, Marcus; Tatham, Peter H
2017-10-01
This study investigates the strategic antecedents of operational agility in humanitarian logistics. It began by identifying the particular actions to be taken at the strategic level of a humanitarian organisation to support field-level agility. Next, quantitative data (n=59) were collected on four strategic-level capabilities (being purposeful, action-focused, collaborative, and learning-oriented) and on operational agility (field responsiveness and flexibility). Using a quantitative analysis, the study tested the relationship between organisational capacity building and operational agility and found that the four strategic-level capabilities are fundamental building blocks of agility. Collectively they account for 52 per cent of the ability of humanitarian logisticians to deal with ongoing changes and disruptions in the field. This study emphasises the need for researchers and practitioners to embrace a broader perspective of agility in humanitarian logistics. In addition, it highlights the inherently strategic nature of agility, the development of which involves focusing simultaneously on multiple drivers. © 2017 The Author(s). Disasters © Overseas Development Institute, 2017.
Chen, Tao; Fan, Jun; Gao, Ruiqi; Wang, Tai; Yu, Ying; Zhang, Weiguang
2016-10-07
Chiral stationary phase-high performance liquid chromatography coupled with various detectors has been one of most commonly used methods for analysis and separation of chiral compounds over the past decades. Various detectors exhibit different characteristics in qualitative and quantitative studies under different chromatographic conditions. Herein, a comparative evaluation of HPLC coupled with ultraviolet, optical rotation, refractive index, and evaporative light scattering detectors has been conducted for qualitative and quantitative analyses of metalaxyl racemate. Effects of separation conditions on the peak area ratio between two enantiomers, including sample concentration, column temperature, mobile phase composition, as well as flow rate, have been investigated in detail. In addition, the limits of detection, the limits of quantitation, quantitative range and precision for these two enantiomers by using four detectors have been also studied. As indicated, the chromatographic separation conditions have been slight effects on ultraviolet and refractive index detections and the peak area ratio between two enantiomers remains almost unchanged, but the evaporative light scattering detection has been significantly affected by the above-mentioned chromatographic conditions and the corresponding peak area ratios varied greatly. Moreover, the limits of detection, the limits of quantitation, and the quantitative ranges of two enantiomers with UV detection were remarkably lower by 1-2 magnitudes than the others. Copyright © 2016 Elsevier B.V. All rights reserved.
Zhao, Xinyan; Dong, Tao
2012-10-16
This study reports a quantitative nucleic acid sequence-based amplification (Q-NASBA) microfluidic platform composed of a membrane-based sampling module, a sample preparation cassette, and a 24-channel Q-NASBA chip for environmental investigations on aquatic microorganisms. This low-cost and highly efficient sampling module, having seamless connection with the subsequent steps of sample preparation and quantitative detection, is designed for the collection of microbial communities from aquatic environments. Eight kinds of commercial membrane filters are relevantly analyzed using Saccharomyces cerevisiae, Escherichia coli, and Staphylococcus aureus as model microorganisms. After the microorganisms are concentrated on the membrane filters, the retentate can be easily conserved in a transport medium (TM) buffer and sent to a remote laboratory. A Q-NASBA-oriented sample preparation cassette is originally designed to extract DNA/RNA molecules directly from the captured cells on the membranes. Sequentially, the extract is analyzed within Q-NASBA chips that are compatible with common microplate readers in laboratories. Particularly, a novel analytical algorithmic method is developed for simple but robust on-chip Q-NASBA assays. The reported multifunctional microfluidic system could detect a few microorganisms quantitatively and simultaneously. Further research should be conducted to simplify and standardize ecological investigations on aquatic environments.
Modeling with Young Students--Quantitative and Qualitative.
ERIC Educational Resources Information Center
Bliss, Joan; Ogborn, Jon; Boohan, Richard; Brosnan, Tim; Mellar, Harvey; Sakonidis, Babis
1999-01-01
A project created tasks and tools to investigate quality and nature of 11- to 14-year-old pupils' reasoning with quantitative and qualitative computer-based modeling tools. Tasks and tools were used in two innovative modes of learning: expressive, where pupils created their own models, and exploratory, where pupils investigated an expert's model.…
Investigation of a redox-sensitive predictive model of mouse embryonic stem cell differentiation via quantitative nuclease protection assays and glutathione redox status Chandler KJ,Hansen JM, Knudsen T,and Hunter ES 1. U.S. Environmental Protection Agency, Research Triangl...
Takahashi, Kazuo H
2017-02-01
Drosophila wings have been a model system to study the effect of HSP90 on quantitative trait variation. The effect of HSP90 inhibition on environmental buffering of wing morphology varies among studies while the genetic buffering effect of it was examined in only one study and was not detected. Variable results so far might show that the genetic background influences the environmental and genetic buffering effect of HSP90. In the previous studies, the number of the genetic backgrounds used is limited. To examine the effect of HSP90 inhibition with a larger number of genetic backgrounds than the previous studies, 20 wild-type strains of Drosophila melanogaster were used in this study. Here I investigated the effect of HSP90 inhibition on the environmental buffering of wing shape and size by assessing within-individual and among-individual variations, and as a result, I found little or very weak effects on environmental and genetic buffering. The current results suggest that the role of HSP90 as a global regulator of environmental and genetic buffering is limited at least in quantitative traits.
Indirect scaling methods for testing quantitative emotion theories.
Junge, Martin; Reisenzein, Rainer
2013-01-01
Two studies investigated the utility of indirect scaling methods, based on graded pair comparisons, for the testing of quantitative emotion theories. In Study 1, we measured the intensity of relief and disappointment caused by lottery outcomes, and in Study 2, the intensity of disgust evoked by pictures, using both direct intensity ratings and graded pair comparisons. The stimuli were systematically constructed to reflect variables expected to influence the intensity of the emotions according to theoretical models of relief/disappointment and disgust, respectively. Two probabilistic scaling methods were used to estimate scale values from the pair comparison judgements: Additive functional measurement (AFM) and maximum likelihood difference scaling (MLDS). The emotion models were fitted to the direct and indirect intensity measurements using nonlinear regression (Study 1) and analysis of variance (Study 2). Both studies found substantially improved fits of the emotion models for the indirectly determined emotion intensities, with their advantage being evident particularly at the level of individual participants. The results suggest that indirect scaling methods yield more precise measurements of emotion intensity than rating scales and thereby provide stronger tests of emotion theories in general and quantitative emotion theories in particular.
Qualitative and quantitative studies of chemical composition of sandarac resin by GC-MS.
Kononenko, I; de Viguerie, L; Rochut, S; Walter, Ph
2017-01-01
The chemical composition of sandarac resin was investigated qualitatively and quantitatively by gas chromatography-mass spectrometry (GC-MS). Six compounds with labdane and pimarane skeletons were identified in the resin. The obtained mass spectra were interpreted and the mass spectrometric behaviour of these diterpenoids under EI conditions was described. Quantitative analysis by the method of internal standard revealed that identified diterpenoids represent only 10-30% of the analysed sample. The sandarac resin from different suppliers was analysed (from Kremer, Okhra, Color Rare, La Marchande de Couleurs, L'Atelier Montessori, Hevea). The analysis of different lumps of resins showed that the chemical composition differs from one lump to another, varying mainly in the relative distributions of the components.
NASA Astrophysics Data System (ADS)
Festa, G.; Senesi, R.; Alessandroni, M.; Andreani, C.; Vitali, G.; Porcinai, S.; Giusti, A. M.; Materna, T.; Paradowska, A. M.
2011-03-01
Quantitative neutron studies of cultural heritage objects provide access to microscopic, mesoscopic, and macroscopic structures in a nondestructive manner. In this paper we present a neutron diffraction investigation of a Ghiberti Renaissance gilded bronze relief devoted to the measurement of cavities and inhomogeneities in the bulk of the sample, along with the bulk phase composition and residual strain distribution. The quantitative measurements allowed the determination of the re-melting parts extension, as well as improving current knowledge about the manufacturing process. The study provides significant and unique information to conservators and restorators about the history of the relief.
Multidisciplinary, interdisciplinary, or dysfunctional? Team working in mixed-methods research.
O'Cathain, Alicia; Murphy, Elizabeth; Nicholl, Jon
2008-11-01
Combining qualitative and quantitative methods in a single study-otherwise known as mixed-methods research-is common. In health research these projects can be delivered by research teams. A typical scenario, for example, involves medical sociologists delivering qualitative components and researchers from medicine or health economics delivering quantitative components. We undertook semistructured interviews with 20 researchers who had worked on mixed-methods studies in health services research to explore the facilitators of and barriers to exploiting the potential of this approach. Team working emerged as a key issue, with three models of team working apparent: multidisciplinary, interdisciplinary, and dysfunctional. Interdisciplinary research was associated with integration of data or findings from the qualitative and quantitative components in both the final reports and the peer-reviewed publications. Methodological respect between team members and a principal investigator who valued integration emerged as essential to achieving integrated research outcomes.
Data capture by digital pen in clinical trials: a qualitative and quantitative study.
Estellat, Candice; Tubach, Florence; Costa, Yolande; Hoffmann, Isabelle; Mantz, Jean; Ravaud, Philippe
2008-05-01
To investigate the use of the digital pen (DP) system to collect data in a clinical trial. To assess the accuracy of the system in this setting. Qualitative study based on semistructured interviews and a focus group. Quantitative study comparing the DP system and a double manual data-entry system in accuracy of acquiring data by variable type (tick boxes, dates, numbers, letters). An ongoing randomised multicentric clinical trial in tertiary care in France. 27 investigators involved in the trial (anaesthetists) who did or did not include patients, 4 study monitors and the study coordinator. Six key findings emerged: 1) the DP system was easy to use; its utilisation was intuitive, even for investigators inexperienced in informatics; 2) despite its portability, the DP was not always used in front of patients; 3) the DP system did not affect patient recruitment; 4) most of the technical problems of the system occurred during setup (compatibility, password access, antivirus software); 5) the main advantage was quickness of data availability for the study coordination staff and the main hindrance was the extra time required for online verification; and 6) all investigators were ready to use the system again. The investigators had to check 16% of data obtained by the DP system during the verification step. There is no relevant difference between the number of errors for the DP and the double manual data-entry systems: 8/5022 versus 6/5022 data entries. 5 out of 8 DP-system failures were due to the intelligent character recognition system. The DP system has a good acceptability among all investigators in a clinical setting, whether they are experienced with computers or not, and a good accuracy, as compared with double manual data entry.
Tsai, Meng-Tsan; Chang, Feng-Yu; Lee, Cheng-Kuang; Gong, Cihun-Siyong Alex; Lin, Yu-Xiang; Lee, Jiann-Der; Yang, Chih-Hsun; Liu, Hao-Li
2014-01-01
Focused ultrasound (FUS) can be used to locally and temporally enhance vascular permeability, improving the efficiency of drug delivery from the blood vessels into the surrounding tissue. However, it is difficult to evaluate in real time the effect induced by FUS and to noninvasively observe the permeability enhancement. In this study, speckle-variance optical coherence tomography (SVOCT) was implemented for the investigation of temporal effects on vessels induced by FUS treatment. With OCT scanning, the dynamic change in vessels during FUS exposure can be observed and studied. Moreover, the vascular effects induced by FUS treatment with and without the presence of microbubbles were investigated and quantitatively compared. Additionally, 2D and 3D speckle-variance images were used for quantitative observation of blood leakage from vessels due to the permeability enhancement caused by FUS, which could be an indicator that can be used to determine the influence of FUS power exposure. In conclusion, SVOCT can be a useful tool for monitoring FUS treatment in real time, facilitating the dynamic observation of temporal effects and helping to determine the optimal FUS power. PMID:25071945
A framing theory-based content analysis of a Turkish newspaper's coverage of nanotechnology
NASA Astrophysics Data System (ADS)
Şenocak, Erdal
2017-07-01
This study aims at examining how nanotechnology is covered in Turkish print media. As an initial part of this objective, a total of 76 articles derived from a widespread national newspaper were analyzed based on the framing theory. These articles were analyzed using both quantitative and qualitative traditions of content analysis; however, the quantitative method was the primary form of investigation. The analyses showed that the first news about nanotechnology appeared in 1991 and the frequencies of articles had increased in the subsequent years; but the number of articles had decreased after a while. The findings demonstrated a remarkable positive tone in the articles; there were only a few articles in negative tones and these articles were published in the first years of nanotechnology news. It was further found that the articles were mostly concerned with the implementations of nanotechnology, such as research and education centers, medical, and electronics. The study also investigated the presentation style of nanotechnology news. In other words, it investigated how the articles were framed. The results showed that the articles were mostly framed with scientific researches or discoveries and future expectations.
NASA Astrophysics Data System (ADS)
Lyu, H.; Ding, L.; Fan, H.; Meng, L.
2017-09-01
Danwei (working unit) and Xiaoqu (residential community) are two typical and unique structural urban elements in China. The interior roads of Danwei and Xiaoqu are usually not accessible for the public. Recently, there is a call for opening these interior roads to the public to improve road network structure and optimize traffic flow. In this paper we investigate the impact of Danwei and Xiaoqu on their neighbouring traffic quantitatively. By taking into consideration of origins and destinations (ODs) distributions and route selection behaviours (e.g., shortest paths), we propose an extended betweenness centrality to investigate the traffic flow in two scenarios 1) the interior roads of Danwei and Xiaoqu are excluded from urban road network, 2) the interior roads are integrated into road network. A Danwei and a Xiaoqu in Shanghai are used as the study area. The preliminary results show the feasibility of our extended betweenness centrality in investigating the traffic flow patterns and reveal the quantitative changes of the traffic flow after opening interior roads.
Fukae, Jun; Kon, Yujiro; Henmi, Mihoko; Sakamoto, Fumihiko; Narita, Akihiro; Shimizu, Masato; Tanimura, Kazuhide; Matsuhashi, Megumi; Kamishima, Tamotsu; Atsumi, Tatsuya; Koike, Takao
2010-05-01
To investigate the relationship between synovial vascularity assessed by quantitative power Doppler sonography (PDS) and progression of structural bone damage in a single finger joint in patients with rheumatoid arthritis (RA). We studied 190 metacarpophalangeal (MCP) joints and 190 proximal interphalangeal (PIP) joints of 19 patients with active RA who had initial treatment with disease-modifying antirheumatic drugs (DMARDs). Patients were examined by clinical and laboratory assessments throughout the study. Hand and foot radiography was performed at baseline and the twentieth week. Magnetic resonance imaging (MRI) was performed at baseline. PDS was performed at baseline and the eighth week. Synovial vascularity was evaluated according to both quantitative and semiquantitative methods. Quantitative PDS was significantly correlated with the enhancement rate of MRI in each single finger joint. Comparing quantitative synovial vascularity and radiographic change in single MCP or PIP joints, the level of vascularity at baseline showed a significant positive correlation with radiographic progression at the twentieth week. The change of vascularity in response to DMARDs, defined as the percentage change in vascularity by the eighth week from baseline, was inversely correlated with radiographic progression in each MCP joint. The quantitative PDS method was more useful than the semiquantitative method for the evaluation of synovial vascularity in a single finger joint. The change of synovial vascularity in a single finger joint determined by quantitative PDS could numerically predict its radiographic progression. Using vascularity as a guide to consider a therapeutic approach would have benefits for patients with active RA.
Schulze, M B; Brandstetter, B R; Kroke, A; Wahrendorf, J; Boeing, H
1999-01-01
The EPIC-Heidelberg and the EPIC-Potsdam studies with about 53,000 study participants represent the German contribution to the EPIC (European Investigation into Cancer and Nutrition) cohort study. Within the EPIC study, standardized 24-hour dietary recalls were applied as a quantitative calibration method in order to estimate the amount of scaling bias introduced by the varying center-specific dietary assessment methods. This article presents intake of food items and food groups in the two German cohorts estimated by 24-hour quantitative dietary recalls. Recalls from 1,013 men and 1,078 women in Heidelberg and 1,032 men and 898 women in Potsdam were included in the analysis. The intake of recorded food items or recipe ingredients as well as fat used for cooking was summarized into 16 main food groups and a variety of different subgroups stratified by sex and weighted for the day of the week and age. In more than 90% of the recalls, consumption of dairy products, cereals and cereal products, bread, fat, and non-alcoholic beverages, particularly coffee/tea, was reported. Inter-cohort evaluations revealed that bread, potatoes, fruit and fat were consumed in higher amounts in the Potsdam cohort while the opposite was found for pasta/rice, non-alcoholic, and alcoholic beverages. It was concluded that the exposure variation was increased by having two instead of one EPIC study centers in Germany. Copyright 1999 S. Karger AG, Basel
Allelic-based gene-gene interaction associated with quantitative traits.
Jung, Jeesun; Sun, Bin; Kwon, Deukwoo; Koller, Daniel L; Foroud, Tatiana M
2009-05-01
Recent studies have shown that quantitative phenotypes may be influenced not only by multiple single nucleotide polymorphisms (SNPs) within a gene but also by the interaction between SNPs at unlinked genes. We propose a new statistical approach that can detect gene-gene interactions at the allelic level which contribute to the phenotypic variation in a quantitative trait. By testing for the association of allelic combinations at multiple unlinked loci with a quantitative trait, we can detect the SNP allelic interaction whether or not it can be detected as a main effect. Our proposed method assigns a score to unrelated subjects according to their allelic combination inferred from observed genotypes at two or more unlinked SNPs, and then tests for the association of the allelic score with a quantitative trait. To investigate the statistical properties of the proposed method, we performed a simulation study to estimate type I error rates and power and demonstrated that this allelic approach achieves greater power than the more commonly used genotypic approach to test for gene-gene interaction. As an example, the proposed method was applied to data obtained as part of a candidate gene study of sodium retention by the kidney. We found that this method detects an interaction between the calcium-sensing receptor gene (CaSR), the chloride channel gene (CLCNKB) and the Na, K, 2Cl cotransporter gene (CLC12A1) that contributes to variation in diastolic blood pressure.
Liu, Kehui; Zhang, Jiyang; Fu, Bin; Xie, Hongwei; Wang, Yingchun; Qian, Xiaohong
2014-07-01
Precise protein quantification is essential in comparative proteomics. Currently, quantification bias is inevitable when using proteotypic peptide-based quantitative proteomics strategy for the differences in peptides measurability. To improve quantification accuracy, we proposed an "empirical rule for linearly correlated peptide selection (ERLPS)" in quantitative proteomics in our previous work. However, a systematic evaluation on general application of ERLPS in quantitative proteomics under diverse experimental conditions needs to be conducted. In this study, the practice workflow of ERLPS was explicitly illustrated; different experimental variables, such as, different MS systems, sample complexities, sample preparations, elution gradients, matrix effects, loading amounts, and other factors were comprehensively investigated to evaluate the applicability, reproducibility, and transferability of ERPLS. The results demonstrated that ERLPS was highly reproducible and transferable within appropriate loading amounts and linearly correlated response peptides should be selected for each specific experiment. ERLPS was used to proteome samples from yeast to mouse and human, and in quantitative methods from label-free to O18/O16-labeled and SILAC analysis, and enabled accurate measurements for all proteotypic peptide-based quantitative proteomics over a large dynamic range. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Hamad, Eradah O; Savundranayagam, Marie Y; Holmes, Jeffrey D; Kinsella, Elizabeth Anne; Johnson, Andrew M
2016-03-08
Twitter's 140-character microblog posts are increasingly used to access information and facilitate discussions among health care professionals and between patients with chronic conditions and their caregivers. Recently, efforts have emerged to investigate the content of health care-related posts on Twitter. This marks a new area for researchers to investigate and apply content analysis (CA). In current infodemiology, infoveillance and digital disease detection research initiatives, quantitative and qualitative Twitter data are often combined, and there are no clear guidelines for researchers to follow when collecting and evaluating Twitter-driven content. The aim of this study was to identify studies on health care and social media that used Twitter feeds as a primary data source and CA as an analysis technique. We evaluated the resulting 18 studies based on a narrative review of previous methodological studies and textbooks to determine the criteria and main features of quantitative and qualitative CA. We then used the key features of CA and mixed-methods research designs to propose the combined content-analysis (CCA) model as a solid research framework for designing, conducting, and evaluating investigations of Twitter-driven content. We conducted a PubMed search to collect studies published between 2010 and 2014 that used CA to analyze health care-related tweets. The PubMed search and reference list checks of selected papers identified 21 papers. We excluded 3 papers and further analyzed 18. Results suggest that the methods used in these studies were not purely quantitative or qualitative, and the mixed-methods design was not explicitly chosen for data collection and analysis. A solid research framework is needed for researchers who intend to analyze Twitter data through the use of CA. We propose the CCA model as a useful framework that provides a straightforward approach to guide Twitter-driven studies and that adds rigor to health care social media investigations. We provide suggestions for the use of the CCA model in elder care-related contexts.
Hamad, Eradah O; Savundranayagam, Marie Y; Holmes, Jeffrey D; Kinsella, Elizabeth Anne
2016-01-01
Background Twitter’s 140-character microblog posts are increasingly used to access information and facilitate discussions among health care professionals and between patients with chronic conditions and their caregivers. Recently, efforts have emerged to investigate the content of health care-related posts on Twitter. This marks a new area for researchers to investigate and apply content analysis (CA). In current infodemiology, infoveillance and digital disease detection research initiatives, quantitative and qualitative Twitter data are often combined, and there are no clear guidelines for researchers to follow when collecting and evaluating Twitter-driven content. Objective The aim of this study was to identify studies on health care and social media that used Twitter feeds as a primary data source and CA as an analysis technique. We evaluated the resulting 18 studies based on a narrative review of previous methodological studies and textbooks to determine the criteria and main features of quantitative and qualitative CA. We then used the key features of CA and mixed-methods research designs to propose the combined content-analysis (CCA) model as a solid research framework for designing, conducting, and evaluating investigations of Twitter-driven content. Methods We conducted a PubMed search to collect studies published between 2010 and 2014 that used CA to analyze health care-related tweets. The PubMed search and reference list checks of selected papers identified 21 papers. We excluded 3 papers and further analyzed 18. Results Results suggest that the methods used in these studies were not purely quantitative or qualitative, and the mixed-methods design was not explicitly chosen for data collection and analysis. A solid research framework is needed for researchers who intend to analyze Twitter data through the use of CA. Conclusions We propose the CCA model as a useful framework that provides a straightforward approach to guide Twitter-driven studies and that adds rigor to health care social media investigations. We provide suggestions for the use of the CCA model in elder care-related contexts. PMID:26957477
Burns, Darren K; Jones, Andrew P; Suhrcke, Marc
2016-03-01
Markets throughout the world have been reducing barriers to international trade and investment in recent years. The resulting increases in levels of international trade and investment have subsequently generated research interest into the potential population health impact. We present a systematic review of quantitative studies investigating the relationship between international trade, foreign direct investment and non-nutritional health outcomes. Articles were systematically collected from the SCOPUS, PubMed, EconLit and Web of Science databases. Due to the heterogeneous nature of the evidence considered, the 16 included articles were subdivided into individual level data analyses, selected country analyses and international panel analyses. Articles were then quality assessed using a tool developed as part of the project. Nine of the studies were assessed to be high quality, six as medium quality, and one as low quality. The evidence from the quantitative literature suggests that overall, there appears to be a beneficial association between international trade and population health. There was also evidence of the importance of foreign direct investment, yet a lack of research considering the direction of causality. Taken together, quantitative research into the relationship between trade and non-nutritional health indicates trade to be beneficial, yet this body of research is still in its infancy. Future quantitative studies based on this foundation will provide a stronger basis on which to inform relevant national and international institutions about the health consequences of trade policies. Copyright © 2016 Elsevier Ltd. All rights reserved.
The Pre-Incubator: A Longitudinal Study of 10 Years of University Pre-Incubation in Wales
ERIC Educational Resources Information Center
Voisey, Pamela; Jones, Paul; Thomas, Brychan
2013-01-01
This paper describes a longitudinal study of over 10 years of university pre-incubation in Wales, using case studies of incubated businesses to track their performance since 2001. Surviving "graduated" businesses were investigated and quantitative and qualitative data were gathered to profile the current status of these businesses and…
ERIC Educational Resources Information Center
Myers, Marion
2012-01-01
This quantitative, non-experimental, correlational study investigated the effects of the Accelerated Reader (AR) program on reading achievement in elementary school students. The study also examined the perceptions of teachers and administrators about the effectiveness of the AR program. This study took place in three elementary schools located in…
Second Language Learners' Performance and Strategies When Writing Direct and Translated Essays
ERIC Educational Resources Information Center
Ismail, Sadiq Abdulwahed Ahmed; Alsheikh, Negmeldin Omer
2012-01-01
The purpose of this study was to investigate ESL students' performance and strategies when writing direct and translated essays. The study also aimed at exploring students' strategies when writing in L2 (English) and L1 (Arabic). The study used a mixture of quantitative and qualitative procedures for data collection and analysis. Adapted strategy…
Can a Tablet Device Alter Undergraduate Science Students' Study Behavior and Use of Technology?
ERIC Educational Resources Information Center
Morris, Neil P.; Ramsay, Luke; Chauhan, Vikesh
2012-01-01
This article reports findings from a study investigating undergraduate biological sciences students' use of technology and computer devices for learning and the effect of providing students with a tablet device. A controlled study was conducted to collect quantitative and qualitative data on the impact of a tablet device on students' use of…
Investigation of Environmental Problem Solving Skills of Preschool Age Children
ERIC Educational Resources Information Center
Ulutas, Aysegül; Köksalan, Bahadir
2017-01-01
The study was conducted to determine problem-solving skills of preschool age children on environment as well as factors affecting this skill. For this purpose, quantitative and qualitative research methods were used together in the study and the research was designed in the screening model. This study is a descriptive type research since it…
The Effects of CMC Applications on ESL Writing Anxiety among Postgraduate Students
ERIC Educational Resources Information Center
Hussin, Supyan; Abdullah, Mohamad Yahya; Ismail, Noriah; Yoke, Soo Kum
2015-01-01
This study investigates the effects of the CMC applications on the ESL/EFL writing anxiety. This is a descriptive study using a mixed-method that adopted both quantitative and qualitative approaches. Three instruments were employed to answer the research questions of the current study which are Second Language Writing Anxiety Inventory (SLWAI),…
Why Study A Level Religious Studies? Qualitative Perspectives from Two English Midlands Sixth Forms
ERIC Educational Resources Information Center
Jones, Ian
2017-01-01
Religious Studies (RS) is expected to impact students' personal development as well as enabling acquisition of knowledge and understanding of religious and philosophical traditions. But to what extent does this actually occur? As part of a larger quantitative investigation of the effects of A Level RS in students' beliefs, values and worldviews…
Silverman, Michael J
2008-01-01
While the music therapy profession is relatively young and small in size, it can treat a variety of clinical populations and has established a diverse research base. However, although the profession originated working with persons diagnosed with mental illnesses, there is a considerable lack of quantitative research concerning the effects of music therapy with this population. Music therapy clinicians and researchers have reported on this lack of evidence and the difficulty in conducting psychosocial research on their interventions (Choi, 1997; Silverman, 2003a). While published studies have provided suggestions for future research, no studies have provided detailed propositions for the methodology and design of meticulous high quality randomized controlled psychiatric music therapy research. How do other psychotherapies accomplish their databases and could the music therapy field borrow from their rigorous "methodological best practices" to strengthen its own literature base? Therefore, as the National Institutes of Mental Health state the treatment of choice for evidence-based psychotherapy is cognitive behavioral therapy (CBT), aspects of this psychotherapy's literature base were analyzed. The purpose of this literature analysis was to (a) analyze and identify components of high-quality quantitative CBT research for adult psychiatric consumers, (b) analyze and identify the variables and other elements of existing quantitative psychiatric music therapy research for adult consumers, and (c) compare the two data sets to identify the best methodological designs and variables for future quantitative music therapy research with the mental health population. A table analyzing randomized and thoroughly controlled studies involving the use of CBT for persons with severe mental illnesses is included to determine chief components of high-quality experimental research designs and implementation of quantitative clinical research. The table also shows the same analyzed components for existing quantitative psychiatric music therapy research with adult consumers, thus highlighting potential areas and elements for future investigations. A second table depicts a number of potential dependent measures and their sources to be evaluated in future music therapy studies. A third table providing suggestions for future research is derived from a synthesis of the tables and is included to guide researchers and encourage the advancement and expansion of the current literature base. The body of the paper is a discussion of the results of the literature analysis derived from the tables, meta-analyses, and reviews of literature. It is hoped that this report will lead to the addition of future high-quality quantitative research to the psychiatric music therapy literature base and thus provide evidence-based services to as many persons with mental illnesses as possible.
Outdoor blue spaces, human health and well-being: A systematic review of quantitative studies.
Gascon, Mireia; Zijlema, Wilma; Vert, Cristina; White, Mathew P; Nieuwenhuijsen, Mark J
2017-11-01
A growing number of quantitative studies have investigated the potential benefits of outdoor blue spaces (lakes, rivers, sea, etc) and human health, but there is not yet a systematic review synthesizing this evidence. To systematically review the current quantitative evidence on human health and well-being benefits of outdoor blue spaces. Following PRISMA guidelines for reporting systematic reviews and meta-analysis, observational and experimental quantitative studies focusing on both residential and non-residential outdoor blue space exposure were searched using specific keywords. In total 35 studies were included in the current systematic review, most of them being classified as of "good quality" (N=22). The balance of evidence suggested a positive association between greater exposure to outdoor blue spaces and both benefits to mental health and well-being (N=12 studies) and levels of physical activity (N=13 studies). The evidence of an association between outdoor blue space exposure and general health (N=6 studies), obesity (N=8 studies) and cardiovascular (N=4 studies) and related outcomes was less consistent. Although encouraging, there remains relatively few studies and a large degree of heterogeneity in terms of study design, exposure metrics and outcome measures, making synthesis difficult. Further research is needed using longitudinal research and natural experiments, preferably across a broader range of countries, to better understand the causal associations between blue spaces, health and wellbeing. Copyright © 2017 Elsevier GmbH. All rights reserved.
Prospective Teachers' Metaphorical Conceptualizations of Learner
ERIC Educational Resources Information Center
Saban, Ahmet
2010-01-01
This study investigated the metaphorical images that prospective teachers in Turkey formulated to describe learners. Participants (N = 2847) completed the prompt "A student is like ... because ..." to indicate their conceptualizations of learner. Data were analyzed both qualitatively and quantitatively. Altogether 98 well-articulated…
ERIC Educational Resources Information Center
Watts, W. J.
1979-01-01
The study involving 70 deaf, 70 partially hearing, and 70 hearing children (10-16 years old) investigated the effect of lack of verbal language on development of deaf children's cognitive abilities. (SBH)
Principals Judge Teachers by Their Teaching
ERIC Educational Resources Information Center
Nixon, Andy; Packard, Abbot; Dam, Margaret
2013-01-01
This quantitative study investigated the relationship between teacher dispositions, subject content knowledge, pedagogical content knowledge, and reasons that school principals recommend non-renewal of probationary teachers' contracts. Principals in the Southeastern Unites States completed an e-mailed survey. Two nonparametric tests,…
3-D Quantitative Dynamic Contrast Ultrasound for Prostate Cancer Localization.
Schalk, Stefan G; Huang, Jing; Li, Jia; Demi, Libertario; Wijkstra, Hessel; Huang, Pintong; Mischi, Massimo
2018-04-01
To investigate quantitative 3-D dynamic contrast-enhanced ultrasound (DCE-US) and, in particular 3-D contrast-ultrasound dispersion imaging (CUDI), for prostate cancer detection and localization, 43 patients referred for 10-12-core systematic biopsy underwent 3-D DCE-US. For each 3-D DCE-US recording, parametric maps of CUDI-based and perfusion-based parameters were computed. The parametric maps were divided in regions, each corresponding to a biopsy core. The obtained parameters were validated per biopsy location and after combining two or more adjacent regions. For CUDI by correlation (r) and for the wash-in time (WIT), a significant difference in parameter values between benign and malignant biopsy cores was found (p < 0.001). In a per-prostate analysis, sensitivity and specificity were 94% and 50% for r, and 53% and 81% for WIT. Based on these results, it can be concluded that quantitative 3-D DCE-US could aid in localizing prostate cancer. Therefore, we recommend follow-up studies to investigate its value for targeting biopsies. Copyright © 2018 World Federation for Ultrasound in Medicine and Biology. Published by Elsevier Inc. All rights reserved.
Quantitative EEG analysis in minimally conscious state patients during postural changes.
Greco, A; Carboncini, M C; Virgillito, A; Lanata, A; Valenza, G; Scilingo, E P
2013-01-01
Mobilization and postural changes of patients with cognitive impairment are standard clinical practices useful for both psychic and physical rehabilitation process. During this process, several physiological signals, such as Electroen-cephalogram (EEG), Electrocardiogram (ECG), Photopletysmography (PPG), Respiration activity (RESP), Electrodermal activity (EDA), are monitored and processed. In this paper we investigated how quantitative EEG (qEEG) changes with postural modifications in minimally conscious state patients. This study is quite novel and no similar experimental data can be found in the current literature, therefore, although results are very encouraging, a quantitative analysis of the cortical area activated in such postural changes still needs to be deeply investigated. More specifically, this paper shows EEG power spectra and brain symmetry index modifications during a verticalization procedure, from 0 to 60 degrees, of three patients in Minimally Consciousness State (MCS) with focused region of impairment. Experimental results show a significant increase of the power in β band (12 - 30 Hz), commonly associated to human alertness process, thus suggesting that mobilization and postural changes can have beneficial effects in MCS patients.
Manevska, Nevena; Stojanoski, Sinisa; Pop Gjorceva, Daniela; Todorovska, Lidija; Miladinova, Daniela; Zafirova, Beti
2017-09-01
Introduction Muscle perfusion is a physiologic process that can undergo quantitative assessment and thus define the range of normal values of perfusion indexes and perfusion reserve. The investigation of the microcirculation has a crucial role in determining the muscle perfusion. Materials and method The study included 30 examinees, 24-74 years of age, without a history of confirmed peripheral artery disease and all had normal findings on Doppler ultrasonography and pedo-brachial index of lower extremity (PBI). 99mTc-MIBI tissue muscle perfusion scintigraphy of lower limbs evaluates tissue perfusion in resting condition "rest study" and after workload "stress study", through quantitative parameters: Inter-extremity index (for both studies), left thigh/right thigh (LT/RT) left calf/right calf (LC/RC) and perfusion reserve (PR) for both thighs and calves. Results In our investigated group we assessed the normal values of quantitative parameters of perfusion indexes. Indexes ranged for LT/RT in rest study 0.91-1.05, in stress study 0.92-1.04. LC/RC in rest 0.93-1.07 and in stress study 0.93-1.09. The examinees older than 50 years had insignificantly lower perfusion reserve of these parameters compared with those younger than 50, LC (p=0.98), and RC (p=0.6). Conclusion This non-invasive scintigraphic method allows in individuals without peripheral artery disease to determine the range of normal values of muscle perfusion at rest and stress condition and to clinically implement them in evaluation of patients with peripheral artery disease for differentiating patients with normal from those with impaired lower limbs circulation.
Relationship between student selection criteria and learner success for medical dosimetry students
DOE Office of Scientific and Technical Information (OSTI.GOV)
Baker, Jamie, E-mail: jabaker@mdanderson.org; Tucker, Debra; Raynes, Edilberto
Medical dosimetry education occupies a specialized branch of allied health higher education. Noted international shortages of health care workers, reduced university funding, limitations on faculty staffing, trends in learner attrition, and increased enrollment of nontraditional students force medical dosimetry educational leadership to reevaluate current admission practices. Program officials wish to select medical dosimetry students with the best chances of successful graduation. The purpose of the quantitative ex post facto correlation study was to investigate the relationship between applicant characteristics (cumulative undergraduate grade point average (GPA), science grade point average (SGPA), prior experience as a radiation therapist, and previous academic degrees)more » and the successful completion of a medical dosimetry program, as measured by graduation. A key finding from the quantitative study was the statistically significant positive correlation between a student's previous degree and his or her successful graduation from the medical dosimetry program. Future research investigations could include a larger research sample, representative of more medical dosimetry student populations, and additional studies concerning the relationship of previous work as a radiation therapist and the effect on success as a medical dosimetry student. Based on the quantitative correlation analysis, medical dosimetry leadership on admissions committees could revise student selection rubrics to place less emphasis on an applicant's undergraduate cumulative GPA and increase the weight assigned to previous degrees.« less
Relationship between student selection criteria and learner success for medical dosimetry students.
Baker, Jamie; Tucker, Debra; Raynes, Edilberto; Aitken, Florence; Allen, Pamela
2016-01-01
Medical dosimetry education occupies a specialized branch of allied health higher education. Noted international shortages of health care workers, reduced university funding, limitations on faculty staffing, trends in learner attrition, and increased enrollment of nontraditional students force medical dosimetry educational leadership to reevaluate current admission practices. Program officials wish to select medical dosimetry students with the best chances of successful graduation. The purpose of the quantitative ex post facto correlation study was to investigate the relationship between applicant characteristics (cumulative undergraduate grade point average (GPA), science grade point average (SGPA), prior experience as a radiation therapist, and previous academic degrees) and the successful completion of a medical dosimetry program, as measured by graduation. A key finding from the quantitative study was the statistically significant positive correlation between a student׳s previous degree and his or her successful graduation from the medical dosimetry program. Future research investigations could include a larger research sample, representative of more medical dosimetry student populations, and additional studies concerning the relationship of previous work as a radiation therapist and the effect on success as a medical dosimetry student. Based on the quantitative correlation analysis, medical dosimetry leadership on admissions committees could revise student selection rubrics to place less emphasis on an applicant׳s undergraduate cumulative GPA and increase the weight assigned to previous degrees. Copyright © 2016 American Association of Medical Dosimetrists. Published by Elsevier Inc. All rights reserved.
Nielsen, Gitte; Fritz-Hansen, Thomas; Dirks, Christina G; Jensen, Gorm B; Larsson, Henrik B W
2004-09-01
To investigate the diagnostic ability of quantitative magnetic resonance imaging (MRI) heart perfusion in acute heart patients, a fast, multislice dynamic contrast-enhanced MRI sequence was applied to patients with acute myocardial infarction. Seven patients with acute transmural myocardial infarction were studied using a Turbo-fast low angle shot (FLASH) MRI sequence to monitor the first pass of an extravascular contrast agent (CA), gadolinium diethylene triamine pentaacetic acid (Gd-DTPA). Quantitation of perfusion, expressed as Ki (mL/100 g/minute), in five slices, each having 60 sectors, provided an estimation of the severity and extent of the perfusion deficiency. Reperfusion was assessed both by noninvasive criteria and by coronary angiography (CAG). The Ki maps clearly delineated the infarction in all patients. Thrombolytic treatment was clearly beneficial in one case, but had no effect in the two other cases. Over the time-course of the study, normal perfusion values were not reestablished following thrombolytic treatment in all cases investigated. This study shows that quantitative MRI perfusion values can be obtained from acutely ill patients following acute myocardial infarction. The technique provides information on both the volume and severity of affected myocardial tissue, enabling the power of treatment regimes to be assessed objectively, and this approach should aid individual patient stratification and prognosis. Copyright 2004 Wiley-Liss, Inc.
ERIC Educational Resources Information Center
Washington, Angela E.
2012-01-01
The purpose of this quantitative correlational study was to investigate the relationship of sociodemographic and personality traits to faculty perceptions and motivations regarding the use of online instruction in radiologic and imaging sciences. A faculty perception and motivations survey of online instruction was administered online in order to…
ERIC Educational Resources Information Center
Peters, Olaf; Körndle, Hermann; Narciss, Susanne
2018-01-01
The purposes of this study are threefold: It investigates effects of a formative assessment script (FAS) that was designed to support vocational students in generating feedback to (1) a peer's and (2) their own performance. Effects of the FAS are investigated with respect to quantitative and qualitative characteristics of the peer and internal…
Doring, Thomas Martin; Granado, Vanessa; Rueda, Fernanda; Deistung, Andreas; Reichenbach, Juergen R; Tukamoto, Gustavo; Gasparetto, Emerson Leandro; Schweser, Ferdinand
2016-01-01
Dysregulation of brain iron homeostasis is a hallmark of many neurodegenerative diseases and can be associated with oxidative stress. The objective of this study was to investigate brain iron in patients with Neuromyelitis Optica (NMO) using quantitative susceptibility mapping (QSM), a quantitative iron-sensitive MRI technique. 12 clinically confirmed NMO patients (6 female and 6 male; age 35.4y±14.2y) and 12 age- and sex-matched healthy controls (7 female and 5 male; age 33.9±11.3y) underwent MRI of the brain at 3 Tesla. Quantitative maps of the effective transverse relaxation rate (R2*) and magnetic susceptibility were calculated and a blinded ROI-based group comparison analysis was performed. Normality of the data and differences between patients and controls were tested by Kolmogorov-Smirnov and t-test, respectively. Correlation with age was studied using Spearman's rank correlation and an ANCOVA-like analysis. Magnetic susceptibility values were decreased in the red nucleus (p<0.01; d>0.95; between -15 and -22 ppb depending on reference region) with a trend toward increasing differences with age. R2* revealed significantly decreased relaxation in the optic radiations of five of the 12 patients (p<0.0001; -3.136±0.567 s-1). Decreased relaxation in the optic radiation is indicative for demyelination, which is in line with previous findings. Decreased magnetic susceptibility in the red nucleus is indicative for a lower brain iron concentration, a chemical redistribution of iron into less magnetic forms, or both. Further investigations are necessary to elucidate the pathological cause or consequence of this finding.
Aslan, Kerim; Gunbey, Hediye Pinar; Tomak, Leman; Ozmen, Zafer; Incesu, Lutfi
The aim of this study was to investigate whether the use of combination quantitative metrics (mamillopontine distance [MPD], pontomesencephalic angle, and mesencephalon anterior-posterior/medial-lateral diameter ratios) with qualitative signs (dural enhancement, subdural collections/hematoma, venous engorgement, pituitary gland enlargements, and tonsillar herniations) provides a more accurate diagnosis of intracranial hypotension (IH). The quantitative metrics and qualitative signs of 34 patients and 34 control subjects were assessed by 2 independent observers. Receiver operating characteristic (ROC) curve was used to evaluate the diagnostic performance of quantitative metrics and qualitative signs, and for the diagnosis of IH, optimum cutoff values of quantitative metrics were found with ROC analysis. Combined ROC curve was measured for the quantitative metrics, and qualitative signs combinations in determining diagnostic accuracy and sensitivity, specificity, and positive and negative predictive values were found, and the best model combination was formed. Whereas MPD and pontomesencephalic angle were significantly lower in patients with IH when compared with the control group (P < 0.001), mesencephalon anterior-posterior/medial-lateral diameter ratio was significantly higher (P < 0.001). For qualitative signs, the highest individual distinctive power was dural enhancement with area under the ROC curve (AUC) of 0.838. For quantitative metrics, the highest individual distinctive power was MPD with AUC of 0.947. The best accuracy in the diagnosis of IH was obtained by combination of dural enhancement, venous engorgement, and MPD with an AUC of 1.00. This study showed that the combined use of dural enhancement, venous engorgement, and MPD had diagnostic accuracy of 100 % for the diagnosis of IH. Therefore, a more accurate IH diagnosis can be provided with combination of quantitative metrics with qualitative signs.
Fosbøl, M; Reving, S; Petersen, E H; Rossing, P; Lajer, M; Zerahn, B
2017-01-01
To investigate whether inclusion of quantitative data on blood flow distribution compared with visual qualitative evaluation improve the reliability and diagnostic performance of 99 m Tc-hydroxymethylene diphosphate three-phase bone scintigraphy (TPBS) in patients suspected for charcot neuropathic osteoarthropathy (CNO) of the foot. A retrospective cohort study of TPBS performed on 148 patients with suspected acute CNO referred from a single specialized diabetes care centre. The quantitative blood flow distribution was calculated based on the method described by Deutsch et al. All scintigraphies were re-evaluated by independent, blinded observers twice with and without quantitative data on blood flow distribution at ankle and focus level, respectively. The diagnostic validity of TPBS was determined by subsequent review of clinical data and radiological examinations. A total of 90 patients (61%) had confirmed diagnosis of CNO. The sensitivity, specificity and accuracy of three-phase bone scintigraphy without/with quantitative data were 89%/88%, 58%/62% and 77%/78%, respectively. The intra-observer agreement improved significantly by adding quantitative data in the evaluation (Kappa value 0·79/0·94). The interobserver agreement was not significantly improved. Adding quantitative data on blood flow distribution in the interpretation of TBPS improves intra-observer variation, whereas no difference in interobserver variation was observed. The sensitivity of TPBS in the diagnosis of CNO is high, but holds limited specificity. Diagnostic performance does not improve using quantitative data in the evaluation. This may be due to the reference intervals applied in the study or the absence of a proper gold standard diagnostic procedure for comparison. © 2015 Scandinavian Society of Clinical Physiology and Nuclear Medicine. Published by John Wiley & Sons Ltd.
ERIC Educational Resources Information Center
Ozsevgec, Lale Cerrah; Azakli, Tugba Kontas
2018-01-01
The purpose of this study is to reveal the relationship among vocational school students' learning attitudes and their socio-demographic features and academic success. Quantitative approach in Relational survey model was used in the study. The sample of the study consists of 82 students who were studying at the Ordu University, during 2015-2016…
ERIC Educational Resources Information Center
Sural, Serhat; Dedebali, Nurhak Cem
2018-01-01
The present study aims to investigate information literacy and curriculum literacy levels of teacher candidates and to identify the relationship between them through their course of study at Faculty of Education. The research model was designed as quantitative one and general screening model was employed. The study group is 895 students, who were…
Physical therapy in Huntington's disease--toward objective assessments?
Bohlen, S; Ekwall, C; Hellström, K; Vesterlin, H; Björnefur, M; Wiklund, L; Reilmann, R
2013-02-01
Physical therapy is recommended for the treatment of Huntington's disease, but reliable studies investigating its efficacy are almost non-existent. This may in part be due to the lack of suitable outcome measures. Therefore, we investigated the applicability of novel quantitative and objective assessments of motor dysfunction in the evaluation of physical therapy interventions aimed at improving gait and posture. Twelve patients with Huntington disease received a predefined twice-weekly intervention focusing on posture and gait over 6 weeks. The GAITRite mat and a force plate were used for objective and quantitative assessments. The Unified Huntingtons Disease Rating Scale Total Motor Score, the timed Up &Go test, and the Berg Balance Scale were used as clinical outcome measures. Significant improvements were seen in GAITRite measures after therapy. Improvements were also seen in the Up & Go test and Berg Balance Scale, whereas force plate measures and Total Motor Scores did not change. The results suggest that physical therapy has a positive effect on gait in Huntington's disease. The study shows that objective and quantitative measures of gait and posture may serve as endpoints in trials assessing the efficacy of physical therapy. They should be explored further in larger trials applying a randomized controlled setting. © 2012 The Author(s) European Journal of Neurology © 2012 EFNS.
Alexis, Matamoro-Vidal; Isaac, Salazar-Ciudad; David, Houle
2015-01-01
One of the aims of evolutionary developmental biology is to discover the developmental origins of morphological variation. The discipline has mainly focused on qualitative morphological differences (e.g., presence or absence of a structure) between species. Studies addressing subtle, quantitative variation are less common. The Drosophila wing is a model for the study of development and evolution, making it suitable to investigate the developmental mechanisms underlying the subtle quantitative morphological variation observed in nature. Previous reviews have focused on the processes involved in wing differentiation, patterning and growth. Here, we investigate what is known about how the wing achieves its final shape, and what variation in development is capable of generating the variation in wing shape observed in nature. Three major developmental stages need to be considered: larval development, pupariation, and pupal development. The major cellular processes involved in the determination of tissue size and shape are cell proliferation, cell death, oriented cell division and oriented cell intercalation. We review how variation in temporal and spatial distribution of growth and transcription factors affects these cellular mechanisms, which in turn affects wing shape. We then discuss which aspects of the wing morphological variation are predictable on the basis of these mechanisms. PMID:25619644
Protein kinetic signatures of the remodeling heart following isoproterenol stimulation.
Lam, Maggie P Y; Wang, Ding; Lau, Edward; Liem, David A; Kim, Allen K; Ng, Dominic C M; Liang, Xiangbo; Bleakley, Brian J; Liu, Chenguang; Tabaraki, Jason D; Cadeiras, Martin; Wang, Yibin; Deng, Mario C; Ping, Peipei
2014-04-01
Protein temporal dynamics play a critical role in time-dimensional pathophysiological processes, including the gradual cardiac remodeling that occurs in early-stage heart failure. Methods for quantitative assessments of protein kinetics are lacking, and despite knowledge gained from single-protein studies, integrative views of the coordinated behavior of multiple proteins in cardiac remodeling are scarce. Here, we developed a workflow that integrates deuterium oxide (2H2O) labeling, high-resolution mass spectrometry (MS), and custom computational methods to systematically interrogate in vivo protein turnover. Using this workflow, we characterized the in vivo turnover kinetics of 2,964 proteins in a mouse model of β-adrenergic-induced cardiac remodeling. The data provided a quantitative and longitudinal view of cardiac remodeling at the molecular level, revealing widespread kinetic regulations in calcium signaling, metabolism, proteostasis, and mitochondrial dynamics. We translated the workflow to human studies, creating a reference dataset of 496 plasma protein turnover rates from 4 healthy adults. The approach is applicable to short, minimal label enrichment and can be performed on as little as a single biopsy, thereby overcoming critical obstacles to clinical investigations. The protein turnover quantitation experiments and computational workflow described here should be widely applicable to large-scale biomolecular investigations of human disease mechanisms with a temporal perspective.
Protein kinetic signatures of the remodeling heart following isoproterenol stimulation
Lam, Maggie P.Y.; Wang, Ding; Lau, Edward; Liem, David A.; Kim, Allen K.; Ng, Dominic C.M.; Liang, Xiangbo; Bleakley, Brian J.; Liu, Chenguang; Tabaraki, Jason D.; Cadeiras, Martin; Wang, Yibin; Deng, Mario C.; Ping, Peipei
2014-01-01
Protein temporal dynamics play a critical role in time-dimensional pathophysiological processes, including the gradual cardiac remodeling that occurs in early-stage heart failure. Methods for quantitative assessments of protein kinetics are lacking, and despite knowledge gained from single-protein studies, integrative views of the coordinated behavior of multiple proteins in cardiac remodeling are scarce. Here, we developed a workflow that integrates deuterium oxide (2H2O) labeling, high-resolution mass spectrometry (MS), and custom computational methods to systematically interrogate in vivo protein turnover. Using this workflow, we characterized the in vivo turnover kinetics of 2,964 proteins in a mouse model of β-adrenergic–induced cardiac remodeling. The data provided a quantitative and longitudinal view of cardiac remodeling at the molecular level, revealing widespread kinetic regulations in calcium signaling, metabolism, proteostasis, and mitochondrial dynamics. We translated the workflow to human studies, creating a reference dataset of 496 plasma protein turnover rates from 4 healthy adults. The approach is applicable to short, minimal label enrichment and can be performed on as little as a single biopsy, thereby overcoming critical obstacles to clinical investigations. The protein turnover quantitation experiments and computational workflow described here should be widely applicable to large-scale biomolecular investigations of human disease mechanisms with a temporal perspective. PMID:24614109
Hospice Care in Nursing Homes: Does It Contribute to Higher Quality Pain Management?
ERIC Educational Resources Information Center
Kayser-Jones, Jeanie S.; Kris, Alison E.; Miaskowski, Christine A.; Lyons, William L.; Paul, Steven M.
2006-01-01
Purpose: The purpose of this study was to investigate pain management among 42 hospice and 65 non-hospice residents in two proprietary nursing homes. Design and Methods: In this prospective, anthropological, quantitative, and qualitative study, we used participant observation, event analysis, and chart review to obtain data. The Medication…
Learning Approaches of Undergraduate Computer Technology Students: Strategies for Improvement
ERIC Educational Resources Information Center
Malakolunthu, Suseela; Joshua, Alice
2012-01-01
Purpose: In recent times, quality of graduates and their performance has been questioned. Students' performance is an indicator of the kind of approach (deep or surface) that is taken. This study investigates the kind of undergraduates take in their learning processes. Methodology: This quantitative survey used Revised Two-Factor Study Process…
Assessing Student Openness to Inquiry-Based Learning in Precalculus
ERIC Educational Resources Information Center
Cooper, Thomas; Bailey, Brad; Briggs, Karen; Holliday, John
2017-01-01
The authors have completed a 2-year quasi-experimental study on the use of inquiry-based learning (IBL) in precalculus. This study included six traditional lecture-style courses and seven modified Moore method courses taught by three instructors. Both quantitative and qualitative analyses were used to investigate the attitudes and beliefs of the…
The Effect of Project Based Learning on Seventh Grade Students' Academic Achievement
ERIC Educational Resources Information Center
Kizkapan, Oktay; Bektas, Oktay
2017-01-01
The purpose of this study is to investigate whether there is a significant effect of project based learning approach on seventh grade students' academic achievement in the structure and properties of matter. In the study, according to the characteristics of quantitative research methods, pretest-posttest control group quasi-experimental design was…
Cooperative Learning for Fostering Knowledge Construction in Japanese High School
ERIC Educational Resources Information Center
Mizuno, Masao
2011-01-01
The purpose of this study is to investigate how cooperative learning approach supports teachers to design an effective teaching for promoting the students learning to construct knowledge in practice. Quantitative and qualitative research methods such as surveys and case studies were employed for data collection. A High School which challenges face…
The Effect of Situated Learning on Students Vocational English Learning
ERIC Educational Resources Information Center
Özüdogru, Melike; Özüdogru, Fatma
2017-01-01
The current study aimed to find out the effect of situated learning on students' Vocational English learning. This research employed a mixed method research design. In the quantitative part of the study, pre-tests and post-tests were implemented to investigate the differences in students' vocational English learning between the experimental and…
The Effect of Single Gender Instruction on Eighth Grade Students' Mathematics Achievement
ERIC Educational Resources Information Center
Hammel, David Michael
2013-01-01
In the research study, this investigator utilized a non-experimental, causal-comparative design (ex post facto) with archival data to determine the real impact single gender instruction had on eighth grade students' mathematics achievement. The purpose of this study was to quantitatively analyze the benefits of single gender mathematics…
ERIC Educational Resources Information Center
Yin, Hongbiao
2015-01-01
Teachers can be seen as emotional workers often needing to be sensitive to the demands that their work makes on their emotions, and skilful in regulating their feelings, but few quantitative studies have examined this issue systematically. Using hierarchical regression analysis to examine this issue, this study investigates teachers' perceptions…
"But What if I Fail?" A Meta-Synthetic Study of the Conditions Supporting Teacher Innovation
ERIC Educational Resources Information Center
Holdsworth, Sally; Maynes, Nancy
2017-01-01
This meta-synthesis investigates the conditions that support teacher innovation in schools. Twenty-seven articles that report on studies using a combination of qualitative and quantitative methodology were selected for this analysis. The articles were analyzed using Hargreaves's and Fullan's concept of "professional capital" as a…
ERIC Educational Resources Information Center
Smith, Prapanna Randall
2013-01-01
This article reports the quantitative phase of a mixed-methods study that was conducted to investigate the relationships between psychosocial learning environments and student satisfaction with their education as mediated by Agentic Personal Meaning. The interdisciplinary approach of the study integrated the fields of learning environment…
Examining the Elements of Online Learning Quality in a Fully Online Doctoral Program
ERIC Educational Resources Information Center
Templeton, Nathan R.; Ballenger, Julia N.; Thompson, J. Ray
2015-01-01
The purpose of this descriptive quantitative study was to examine the quality elements of online learning in a regional doctoral program. Utilizing the six quality dimensions of Hathaway's (2009) theory of online learning quality as a framework, the study investigated instructor-learner, learner-learner, learner-content, learner-interface,…
An Investigation of Personality Traits in Relation to Job Performance of Online Instructors
ERIC Educational Resources Information Center
Holmes, Charles; Kirwan, Jeral R.; Bova, Mark; Belcher, Trevor
2015-01-01
This quantitative study examined the relationship between the Big 5 personality traits and how they relate to online teacher effectiveness. The primary method of data collection for this study was through the use of surveys primarily building upon the Personality Style Inventory (PSI) (Lounsbury & Gibson, 2010), a work-based personality…
The Professionalization of Dental Students: The Application of Socio-Anthropological Methodology.
ERIC Educational Resources Information Center
Platt, Larry A.; Bailey, Wilfrid C.
This paper discusses the advantages of using both qualitative and quantitative methodological procedures in investigating attitudinal and perception changes in the population studied. This project is part of a 4-year longitudinal study involving 24 dental students and 29 faculty members of a new southern dental school. The paper reviews some of…
How Tinto's Theory Differs for Asian and Non-Asian International Students: A Quantitative Study
ERIC Educational Resources Information Center
Kommers, Suzan; Pham, Duy
2016-01-01
Literature suggests that international students from Asian countries might differ in the way they can be supported in their efforts towards completing their degree. Using the 2004/09 Beginning Postsecondary Students Longitudinal Study, the authors investigate how social and academic integration relate to the college persistence of Asian and…
An Empirical Investigation of Campus Portal Usage
ERIC Educational Resources Information Center
Saghapour, Mohsen; Iranmanesh, Mohammad; Zailani, Suhaiza; Goh, Gerald Guan Gan
2018-01-01
This study has determined the determinants of the perceived ease of use and perceived usefulness and their influence on campus portal usage. A quantitative approach was employed, using a five-point Likert scale questionnaire, adapted from previous studies. Data were gathered through a survey conducted with 341 staff working in the University of…
Language Learning Strategies Profiles of EFL Learners in Nepal
ERIC Educational Resources Information Center
Dawadi, Saraswati
2017-01-01
This study investigated language learning strategies (LLS) used by English as foreign language (EFL) learners in Nepal. For this study, 370 undergraduate level students from a university in Nepal responded to a questionnaire. The quantitative software SPSS was used to analyse the data. Results indicated that students were moderate users of those…
Book Reading Styles in Dual-Parent and Single-Mother Families
ERIC Educational Resources Information Center
Blake, Joanna; Macdonald, Silvana; Bayrami, Lisa; Agosta, Vanessa; Milian, Andrea
2006-01-01
Background: Whereas many studies have investigated quantitative aspects of book reading (frequency), few have examined qualitative aspects, especially in very young children and through direct observations of shared reading. Aim: The purpose of this study was to determine possible differences in book-reading styles between mothers and fathers and …
ERIC Educational Resources Information Center
Stanley, Nile; Nguyen, Kate; Wilson, Hope; Stanley, Laurel; Rank, Astrid; Wang, Yonghui
2015-01-01
Numerous qualitative studies, mostly with English speaking Westerners, have shown the important role of storytelling and values in promoting resilience. However, this quantitative study helps fill the gaps in the research, by investigating the mediator effects of storytelling on values and resilience of American, German, Chinese, and Vietnamese…
Factors Associated with Transfer of Training in Workplace E-Learning
ERIC Educational Resources Information Center
Park, Ji-Hye; Wentling, Tim
2007-01-01
Purpose--The purpose of this study is to investigate the effect of factors associated with e-learning, particularly computer attitudes and usability, on transfer of training in workplace e-learning courses. Design/methodology/approach--This study relied on quantitative data obtained from four online survey questionnaires. The sample of this study…
Measuring College Success for International Baccalaureate Diploma and Certificate Candidates
ERIC Educational Resources Information Center
Hill, Jennifer Coles
2018-01-01
This quantitative study was conducted at a private international high school. The study purpose was to investigate United States college trends comparing International Baccalaureate Diploma Program candidates and International Baccalaureate Non-Diploma Program candidates from the same school in Asia. Data was collected for the Classes of 2007-2012…
Digital Textbooks: A Study of Factors Affecting College Student Adoption
ERIC Educational Resources Information Center
Barajas-Murphy, Noreen
2017-01-01
Purpose: The purpose of this quantitative research study was to examine the factors that influence students' intentions to continue to use digital texts. Specifically, the purpose was to investigate what impact the external factors of instructor modeling and instructor expectation to use had on the intention to continue to use digital textbooks as…
Predicting Southern Appalachian overstory vegetation with digital terrain data
Paul V. Bolstad; Wayne Swank; James Vose
1998-01-01
Vegetation in mountainous regions responds to small-scale variation in terrain, largely due to effects on both temperature and soil moisture. However, there are few studies of quantitative, terrain-based methods for predicting vegetation composition. This study investigated relationships between forest composition, elevation, and a derived index of terrain shape, and...
ERIC Educational Resources Information Center
Matthews, Kelly E.; Firn, Jennifer; Schmidt, Susanne; Whelan, Karen
2017-01-01
This study investigated students' perceptions of their graduate learning outcomes including content knowledge, communication, writing, teamwork, quantitative skills, and ethical thinking in two Australian universities. One university has a traditional discipline-orientated curriculum and the other, an interdisciplinary curriculum in the entry…
Using Inquiry-Based Strategies for Enhancing Students' STEM Education Learning
ERIC Educational Resources Information Center
Lai, Ching-San
2018-01-01
The major purpose of this study was to investigate whether or not the inquiry-based method is effective in improving students' learning in STEM (Science, Technology, Engineering, and Mathematics) education. Both quantitative and qualitative methods were used. A total of 73 college students studying Information Technology (IT) were chosen as…
A Study of Early Childhood Mathematics Teaching in the United States and China
ERIC Educational Resources Information Center
Li, Xia; Chi, Liping; DeBey, Mary; Baroody, Arthur J.
2015-01-01
Research Findings: The present study involved using a questionnaire to investigate the mathematics teaching practices of 74 U.S. and 67 Chinese early childhood teachers. Quantitative and qualitative analyses yielded several key findings. First, U.S. teachers are less intentional in mathematics teaching than their Chinese counterparts.…
ERIC Educational Resources Information Center
Aydin, Hasan
2013-01-01
The purpose of this study is to determine learners' and instructors' perceptions about technology-enhanced learning environment. This study uses both quantitative and qualitative methods. A Likert-scale survey was developed and administered to 48 Turkish language learners in various language courses in Istanbul to investigate their perceptions of…
Improving Classroom Learning: The Effectiveness of Time Delay within the TEACCH Approach
ERIC Educational Resources Information Center
Kurt, Onur; Parsons, Chris
2009-01-01
The present study investigated the effects of a constant time delay (CTD) strategy within a TEACCH approach and the views of the classroom teacher surrounding the teaching process. Three male students with autism participated in the study. Both qualitative and quantitative methods were used to collect and analyze data. Although experimental…
ERIC Educational Resources Information Center
Ferdinandi, Andrew D.; Bethea, James S.
2006-01-01
The purpose of this quantitative study was to investigate the effect of Counselor Active Rehabilitation Service (CARS), compared to standard rehabilitation counseling in reducing feelings of hopelessness in individuals with substance abuse disorders. This study involved 50 inner city participants with substance abuse disorders. As determined using…
A Study of Factors That Influence Job Satisfaction of Teachers at a Southeast Christian School
ERIC Educational Resources Information Center
Churchwell, Mark S.
2016-01-01
This quantitative study investigated factors that influence the job satisfaction of teachers at a large K-12 Christian school. Selected demographic variables (gender, marital status, grade level taught, and years of teaching experience) were examined for their relationships with teacher job satisfaction. The following overarching question guided…
A Longitudinal, Quantitative Study of Student Attitudes towards Audio Feedback for Assessment
ERIC Educational Resources Information Center
Parkes, Mitchell; Fletcher, Peter
2017-01-01
This paper reports on the findings of a three-year longitudinal study investigating the experiences of postgraduate level students who were provided with audio feedback for their assessment. Results indicated that students positively received audio feedback. Overall, students indicated a preference for audio feedback over written feedback. No…
ERIC Educational Resources Information Center
Mohr-Schroeder, Margaret J.; Jackson, Christa; Cavalcanti, Maureen; Jong, Cindy; Schroeder, D. Craig; Speler, Lydia G.
2017-01-01
The purpose of this study was to investigate parents' attitudes toward mathematics, their students' attitude toward mathematics, and the influence of the parents' attitude on the students' attitude toward mathematics. Data analyses revealed statistically significant positive correlations between parents' and students' attitudes toward mathematics.…
How Safe Is a School? An Exploratory Study Comparing Measures and Perceptions of Safety
ERIC Educational Resources Information Center
Hernandez, Diley; Floden, Lysbeth; Bosworth, Kris
2010-01-01
This exploratory study investigates the relation between incident reports to local law enforcement, and students' and teachers' perceptions of school safety. Using a combination of grounded theory and statistics, we compared quantitative data collected from law enforcement agencies with qualitative data provided by students and teachers during…
Lu, Pei-Pei; Ting, Shing-Shiang; Chen, Mei-Ling; Tang, Woung-Ru
2005-12-01
The purpose of this study is to discuss the historical context of qualitative and quantitative research so as to explain the principle of qualitative study and examine the positioning of nursing research within academic study as a whole. This paper guides the readers towards the historical context from empirical science, discusses the influences of qualitative and quantitative research on nursing research, then investigates the nature of research paradigms, examines the positioning of nursing research, which includes the characteristics of fields such as natural science, humanity and social studies, and science, and lastly, presents the research standard proposed by Yardley in 2000. The research paradigms include Positivism, Postpositivism, Criticism, and Constructivism, which can be compared with Ontology, Epistemology, and Methodology. The nature of the paradigm is to determine the assumption of the paradigm on the basis of Ontology, Epistemology, and Methodology. The paradigm determines how the researcher views the world and decides on what to answer, how to research, and how to answer. The difference in academic environment is reflected in the long-term dialogue between qualitative and quantitative studies, as well as the standard for criticism. This paper introduces the method of evaluation of the quality of qualitative study proposed by Yardley in 2002, namely the sensitivity of the context, the promise and conscientiousness, transparency and consistency, influence and significance. The paper is intended to provide a guideline for readers in evaluating the quality of qualitative study.
Canales, Janette Z; Fiquer, Juliana T; Campos, Rodolfo N; Soeiro-de-Souza, Márcio Gerhardt; Moreno, Ricardo Alberto
2017-02-01
The aim of this study was to investigate associations between poor spinal posture and the recurrence of major depressive episodes and severity of symptoms in patients with major depressive disorder (MDD). This was a cross-sectional quantitative study of MDD patients. Outpatients were recruited from consecutive admissions at a mood disorders unit of a tertiary psychiatric hospital. Of 136 MDD patients, 72 (53 women, 19 men; mean age, 42.4±9.1years) met all the criteria and completed the study. Forty-one patients were classified with a recurrent episode (RE) of MDD and 31 with a single episode (SE). Quantitative assessments of postural deviations were made using photogrammetry, including kyphosis, shoulder protraction, and head inclination. The severity of depressive episodes was assessed using the Hamilton Depression Rating Scale. The diagnosis and classification of patients were performed according to DSM-IV-TR and SCID criteria. Multivariate analysis of variance indicated that the RE group had greater anterior head inclination (35.39; SD: 1.57), greater scapular abduction (1.69; SD: 0.93), and worse thoracic kyphosis (139.38; SD: 1.19) than the SE group (p<0.001 for all). Multivariate analysis of covariance showed an interaction between the severity of depressive symptoms and the degree of thoracic kyphosis (p=0.002). Recurrence of depressive episodes is associated with measures of postural misalignment. Copyright © 2016 Elsevier B.V. All rights reserved.
Bovens, M; Csesztregi, T; Franc, A; Nagy, J; Dujourdy, L
2014-01-01
The basic goal in sampling for the quantitative analysis of illicit drugs is to maintain the average concentration of the drug in the material from its original seized state (the primary sample) all the way through to the analytical sample, where the effect of particle size is most critical. The size of the largest particles of different authentic illicit drug materials, in their original state and after homogenisation, using manual or mechanical procedures, was measured using a microscope with a camera attachment. The comminution methods employed included pestle and mortar (manual) and various ball and knife mills (mechanical). The drugs investigated were amphetamine, heroin, cocaine and herbal cannabis. It was shown that comminution of illicit drug materials using these techniques reduces the nominal particle size from approximately 600 μm down to between 200 and 300 μm. It was demonstrated that the choice of 1 g increments for the primary samples of powdered drugs and cannabis resin, which were used in the heterogeneity part of our study (Part I) was correct for the routine quantitative analysis of illicit seized drugs. For herbal cannabis we found that the appropriate increment size was larger. Based on the results of this study we can generally state that: An analytical sample weight of between 20 and 35 mg of an illicit powdered drug, with an assumed purity of 5% or higher, would be considered appropriate and would generate an RSDsampling in the same region as the RSDanalysis for a typical quantitative method of analysis for the most common, powdered, illicit drugs. For herbal cannabis, with an assumed purity of 1% THC (tetrahydrocannabinol) or higher, an analytical sample weight of approximately 200 mg would be appropriate. In Part III we will pull together our homogeneity studies and particle size investigations and use them to devise sampling plans and sample preparations suitable for the quantitative instrumental analysis of the most common illicit drugs. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.
Wang, Chunhao; Yin, Fang-Fang; Kirkpatrick, John P; Chang, Zheng
2017-08-01
To investigate the feasibility of using undersampled k-space data and an iterative image reconstruction method with total generalized variation penalty in the quantitative pharmacokinetic analysis for clinical brain dynamic contrast-enhanced magnetic resonance imaging. Eight brain dynamic contrast-enhanced magnetic resonance imaging scans were retrospectively studied. Two k-space sparse sampling strategies were designed to achieve a simulated image acquisition acceleration factor of 4. They are (1) a golden ratio-optimized 32-ray radial sampling profile and (2) a Cartesian-based random sampling profile with spatiotemporal-regularized sampling density constraints. The undersampled data were reconstructed to yield images using the investigated reconstruction technique. In quantitative pharmacokinetic analysis on a voxel-by-voxel basis, the rate constant K trans in the extended Tofts model and blood flow F B and blood volume V B from the 2-compartment exchange model were analyzed. Finally, the quantitative pharmacokinetic parameters calculated from the undersampled data were compared with the corresponding calculated values from the fully sampled data. To quantify each parameter's accuracy calculated using the undersampled data, error in volume mean, total relative error, and cross-correlation were calculated. The pharmacokinetic parameter maps generated from the undersampled data appeared comparable to the ones generated from the original full sampling data. Within the region of interest, most derived error in volume mean values in the region of interest was about 5% or lower, and the average error in volume mean of all parameter maps generated through either sampling strategy was about 3.54%. The average total relative error value of all parameter maps in region of interest was about 0.115, and the average cross-correlation of all parameter maps in region of interest was about 0.962. All investigated pharmacokinetic parameters had no significant differences between the result from original data and the reduced sampling data. With sparsely sampled k-space data in simulation of accelerated acquisition by a factor of 4, the investigated dynamic contrast-enhanced magnetic resonance imaging pharmacokinetic parameters can accurately estimate the total generalized variation-based iterative image reconstruction method for reliable clinical application.
Preschool Teachers' Views about Classroom Management Models
ERIC Educational Resources Information Center
Sahin-Sak, Ikbal Tuba; Sak, Ramazan; Tezel-Sahin, Fatma
2018-01-01
This survey-based quantitative study investigates 310 Turkish preschool teachers' views about classroom management, using the following six models of disciplinary strategy: behavioral change theory, Dreikurs' social discipline model, Canter's assertive discipline model, the Glasser model of discipline, Kounin's model, and Gordon's teacher…
NASA Technical Reports Server (NTRS)
Bar-Cohen, Y.; Mal, A.; Chang, Z.
1998-01-01
The phenomenon of Leaky Lamb Wave (LLW) in composite materials was first observed in 1982 using a Schlieren system. It has been studied extensively by numerous investigators and successfully shown to be an effective quantitative NDE tool.
Effects of Embedded Processing Tasks on Learning Outcomes.
ERIC Educational Resources Information Center
Hobbs, D. J.
1987-01-01
Describes a British study with undergraduate accountancy students which compared the quantitative and qualitative effects of three types of embedded tasks or questions--relational-semantic, transpose-semantic, and non-semantic--on learning outcomes. Variables investigated included mathematical background, recall, and comprehension. Relevance of…
Investigation of Post-mortem Tissue Effects Using Long-time Decorrelation Ultrasound
NASA Astrophysics Data System (ADS)
Csány, Gergely; Balogh, Lajos; Gyöngy, Miklós
Decorrelation ultrasound is being increasingly used to investigate long-term biological phenomena. In the current work, ultrasound image sequences of mice who did not survive anesthesia (in a separate investigation) were analyzed and post-mortem tissue effects were observed via decorrelation calculation. A method was developed to obtain a quantitative parameter characterizing the rate of decorrelation. The results show that ultrasound decorrelation imaging is an effective method of observing post-mortem tissue effects and point to further studies elucidating the mechanism behind these effects.
ERIC Educational Resources Information Center
Grim, Brian J.; Harmon, Alison H.; Gromis, Judy C.
2006-01-01
There is a sharp divide between quantitative and qualitative methodologies in the social sciences. We investigate an innovative way to bridge this gap that incorporates quantitative techniques into a qualitative method, the "quanti-qualitative method" (QQM). Specifically, our research utilized small survey questionnaires and experiment-like…
NASA Astrophysics Data System (ADS)
Esposito, Alessandro
2006-05-01
This PhD project aims at the development and evaluation of microscopy techniques for the quantitative detection of molecular interactions and cellular features. The primarily investigated techniques are Fαrster Resonance Energy Transfer imaging and Fluorescence Lifetime Imaging Microscopy. These techniques have the capability to quantitatively probe the biochemical environment of fluorophores. An automated microscope capable of unsupervised operation has been developed that enables the investigation of molecular and cellular properties at high throughput levels and the analysis of cellular heterogeneity. State-of-the-art Förster Resonance Energy Transfer imaging, Fluorescence Lifetime Imaging Microscopy, Confocal Laser Scanning Microscopy and the newly developed tools have been combined with cellular and molecular biology techniques for the investigation of protein-protein interactions, oligomerization and post-translational modifications of α-Synuclein and Tau, two proteins involved in Parkinson’s and Alzheimer’s disease, respectively. The high inter-disciplinarity of this project required the merging of the expertise of both the Molecular Biophysics Group at the Debye Institute - Utrecht University and the Cell Biophysics Group at the European Neuroscience Institute - Gαttingen University. This project was conducted also with the support and the collaboration of the Center for the Molecular Physiology of the Brain (Göttingen), particularly with the groups associated with the Molecular Quantitative Microscopy and Parkinson’s Disease and Aggregopathies areas. This work demonstrates that molecular and cellular quantitative microscopy can be used in combination with high-throughput screening as a powerful tool for the investigation of the molecular mechanisms of complex biological phenomena like those occurring in neurodegenerative diseases.
Julkunen, Petro; Kiviranta, Panu; Wilson, Wouter; Jurvelin, Jukka S; Korhonen, Rami K
2007-01-01
Load-bearing characteristics of articular cartilage are impaired during tissue degeneration. Quantitative microscopy enables in vitro investigation of cartilage structure but determination of tissue functional properties necessitates experimental mechanical testing. The fibril-reinforced poroviscoelastic (FRPVE) model has been used successfully for estimation of cartilage mechanical properties. The model includes realistic collagen network architecture, as shown by microscopic imaging techniques. The aim of the present study was to investigate the relationships between the cartilage proteoglycan (PG) and collagen content as assessed by quantitative microscopic findings, and model-based mechanical parameters of the tissue. Site-specific variation of the collagen network moduli, PG matrix modulus and permeability was analyzed. Cylindrical cartilage samples (n=22) were harvested from various sites of the bovine knee and shoulder joints. Collagen orientation, as quantitated by polarized light microscopy, was incorporated into the finite-element model. Stepwise stress-relaxation experiments in unconfined compression were conducted for the samples, and sample-specific models were fitted to the experimental data in order to determine values of the model parameters. For comparison, Fourier transform infrared imaging and digital densitometry were used for the determination of collagen and PG content in the same samples, respectively. The initial and strain-dependent fibril network moduli as well as the initial permeability correlated significantly with the tissue collagen content. The equilibrium Young's modulus of the nonfibrillar matrix and the strain dependency of permeability were significantly associated with the tissue PG content. The present study demonstrates that modern quantitative microscopic methods in combination with the FRPVE model are feasible methods to characterize the structure-function relationships of articular cartilage.
Thermodynamics and Mechanics of Membrane Curvature Generation and Sensing by Proteins and Lipids
Baumgart, Tobias; Capraro, Benjamin R.; Zhu, Chen; Das, Sovan L.
2014-01-01
Research investigating lipid membrane curvature generation and sensing is a rapidly developing frontier in membrane physical chemistry and biophysics. The fast recent progress is based on the discovery of a plethora of proteins involved in coupling membrane shape to cellular membrane function, the design of new quantitative experimental techniques to study aspects of membrane curvature, and the development of analytical theories and simulation techniques that allow a mechanistic interpretation of quantitative measurements. The present review first provides an overview of important classes of membrane proteins for which function is coupled to membrane curvature. We then survey several mechanisms that are assumed to underlie membrane curvature sensing and generation. Finally, we discuss relatively simple thermodynamic/mechanical models that allow quantitative interpretation of experimental observations. PMID:21219150
Olokundun, Maxwell; Iyiola, Oluwole; Ibidunni, Stephen; Ogbari, Mercy; Falola, Hezekiah; Salau, Odunayo; Peter, Fred; Borishade, Taiye
2018-06-01
The article presented data on the effectiveness of entrepreneurship curriculum contents on university students' entrepreneurial interest and knowledge. The study focused on the perceptions of Nigerian university students. Emphasis was laid on the first four universities in Nigeria to offer a degree programme in entrepreneurship. The study adopted quantitative approach with a descriptive research design to establish trends related to the objective of the study. Survey was be used as quantitative research method. The population of this study included all students in the selected universities. Data was analyzed with the use of Statistical Package for Social Sciences (SPSS). Mean score was used as statistical tool of analysis. The field data set is made widely accessible to enable critical or a more comprehensive investigation.
Iron in Multiple Sclerosis and Its Noninvasive Imaging with Quantitative Susceptibility Mapping
Stüber, Carsten; Pitt, David; Wang, Yi
2016-01-01
Iron is considered to play a key role in the development and progression of Multiple Sclerosis (MS). In particular, iron that accumulates in myeloid cells after the blood-brain barrier (BBB) seals may contribute to chronic inflammation, oxidative stress and eventually neurodegeneration. Magnetic resonance imaging (MRI) is a well-established tool for the non-invasive study of MS. In recent years, an advanced MRI method, quantitative susceptibility mapping (QSM), has made it possible to study brain iron through in vivo imaging. Moreover, immunohistochemical investigations have helped defining the lesional and cellular distribution of iron in MS brain tissue. Imaging studies in MS patients and of brain tissue combined with histological studies have provided important insights into the role of iron in inflammation and neurodegeneration in MS. PMID:26784172
el-Ebiary, M; Torres, A; González, J; de la Bellacasa, J P; García, C; Jiménez de Anta, M T; Ferrer, M; Rodriguez-Roisin, R
1993-12-01
Bronchoalveolar lavage (BAL) and protected specimen brushing (PSB) are the most commonly used methods for diagnosing ventilator-associated (VA) pneumonia although they require bronchoscopy. Endotracheal aspiration (EA) is a simple and less costly technique than PSB or BAL. The purpose of our study was to investigate the diagnostic value of EA quantitative cultures and to compare the results obtained using EA with those obtained using PSB and BAL in mechanically ventilated patients with or without pneumonia. We prospectively studied 102 intubated patients divided into three diagnostic categories: Group I (definite pneumonia, n = 26), Group II (uncertain status, n = 48), and Group III (control group, n = 28). All patients received prior antibiotic treatment. EA, PSB, and BAL were obtained sequentially in all patients. When comparing Group I with Group III and using 10(5) cfu/ml as a threshold, we found that EA quantitative cultures represented a relatively sensitive (70%) and relatively specific (72%) method to diagnose VA pneumonia. The specificity of BAL and PSB (87% and 93%, respectively) was better than that of EA. The negative predictive value of EA cultures was higher (72%) when compared with that obtained using PSB (34%) (p < 0.05). EA quantitative cultures correlated with PSB and BAL quantitative cultures in patients with definite pneumonia. Although EA quantitative cultures are less specific than PSB and BAL for diagnosing VA pneumonia, our results suggest that the former approach may be used to treat these patients when bronchoscopic procedures are not available.
ERIC Educational Resources Information Center
Park, Soonhye; Jang, Jeong-Yoon; Chen, Ying-Chih; Jung, Jinhong
2011-01-01
This study tested a hypothesis that focused on whether or not teachers' pedagogical content knowledge (PCK) is a necessary body of knowledge for reformed science teaching. This study utilized a quantitative research method to investigate the correlation between a teacher's PCK level as measured by the PCK rubric (Park et al. 2008) and the degree…
ERIC Educational Resources Information Center
Karr, Carolyn A.; Larson, Lisa M.
2005-01-01
Three major journals in counseling psychology were sampled from 1990 to 1999 to assess the percentage of quantitative, empirical articles that were theory driven. Only 43% of the studies utilized a theory or model, and 57% predicted the relation between the variables, with few studies specifying the strength of the relation. Studies sampled in the…
ERIC Educational Resources Information Center
Yeni, Sabiha; Ozdener, Nesrin
2014-01-01
The purpose of the study is to investigate how pre-service teachers benefit from learning objects repositories while preparing course content. Qualitative and quantitative data collection methods were used in a mixed methods approach. This study was carried out with 74 teachers from the Faculty of Education. In the first phase of the study,…
ERIC Educational Resources Information Center
Nikoonezhad, Sepideh; Nili, Mohammadreza; Esfahani, Ahmadreza Nasr
2015-01-01
The present study aims at investigating barriers upon development of virtual education in engineering majors at the University of Isfahan. The study has applied a mixed method (qualitative and quantitative) and its population consists all of the department members of the technical and engineering majors at the University of Isfahan including 125…
ERIC Educational Resources Information Center
Akgün, Ismail Hakan
2016-01-01
The aim of this research is to determine Social Studies teacher candidates' intended uses of social networks in terms of various variables. The research was carried out by using screening model of quantitative research methods. In the study, "The Social Network Intended Use Scale" was used as a data collection tool. As a result of the…
ERIC Educational Resources Information Center
Kaskaya, Alper; Unlu, Ihsan; Akar, M. Said; Ozturan Sagirli, Meryem
2011-01-01
The aim of this study is to investigate the effects of school and teacher themed movies on pre-service teachers' attitudes towards their profession and their perceived self-efficacy. As qualitative and quantitative research approaches were employed during data collection procedure, mixed methodology was adopted in this study. In the study, one of…
Anxiety in English Language Learning: A Case Study of English Language Learners in Saudi Arabia
ERIC Educational Resources Information Center
Sadiq, Jamilah Mohammed
2017-01-01
Language anxiety as a specific aspect of language acquisition has occupied a great body of research for the past few decades. In this study, the level of foreign language anxiety among English language learners was investigated. This study was carried out with a quantitative research design using a survey methodology to collect data about the…
ERIC Educational Resources Information Center
White, April L.
2013-01-01
Many organizations find selecting a leader to be highly challenging. Investigators have found and admit that the study of leadership is a very complex phenomenon that cannot be easily captured and explained in a manner that could lead to a final description about leadership or offer clear steps on how to choose the right leader. Among the many…
NASA Astrophysics Data System (ADS)
Edward, Kert
Quantitative phase microscopy (QPM) allows for the imaging of translucent or transparent biological specimens without the need for exogenous contrast agents. This technique is usually applied towards the investigation of simple cells such as red blood cells which are typically enucleated and can be considered to be homogenous. However, most biological cells are nucleated and contain other interesting intracellular organelles. It has been established that the physical characteristics of certain subsurface structures such as the shape and roughness of the nucleus is well correlated with onset and progress of pathological conditions such as cancer. Although the acquired quantitative phase information of biological cells contains surface information as well as coupled subsurface information, the latter has been ignored up until now. A novel scanning quantitative phase imaging system unencumbered by 2pi ambiguities is hereby presented. This system is incorporated into a shear-force feedback scheme which allows for simultaneous phase and topography determination. It will be shown how subsequent image processing of these two data sets allows for the extraction of the subsurface component in the phase data and in vivo cell refractometry studies. Both fabricated samples and biological cells ranging from rat fibroblast cells to malaria infected human erythrocytes were investigated as part of this research. The results correlate quite well with that obtained via other microscopy techniques.
ERIC Educational Resources Information Center
Türkçapar, Ünal
2015-01-01
The purpose of this study is to investigate the state and private school students' achievement goal orientation levels in terms of some variables. Quantitative survey method was used in this study. Study group in this research consists of 201 students who are studying at state and private school in Kahramanmaras during the 2014-2015 academic year.…
Peeters, Michael J; Vaidya, Varun A
2016-06-25
Objective. To describe an approach for assessing the Accreditation Council for Pharmacy Education's (ACPE) doctor of pharmacy (PharmD) Standard 4.4, which focuses on students' professional development. Methods. This investigation used mixed methods with triangulation of qualitative and quantitative data to assess professional development. Qualitative data came from an electronic developmental portfolio of professionalism and ethics, completed by PharmD students during their didactic studies. Quantitative confirmation came from the Defining Issues Test (DIT)-an assessment of pharmacists' professional development. Results. Qualitatively, students' development reflections described growth through this course series. Quantitatively, the 2015 PharmD class's DIT N2-scores illustrated positive development overall; the lower 50% had a large initial improvement compared to the upper 50%. Subsequently, the 2016 PharmD class confirmed these average initial improvements of students and also showed further substantial development among students thereafter. Conclusion. Applying an assessment for learning approach, triangulation of qualitative and quantitative assessments confirmed that PharmD students developed professionally during this course series.
Detecting Genetic Interactions for Quantitative Traits Using m-Spacing Entropy Measure
Yee, Jaeyong; Kwon, Min-Seok; Park, Taesung; Park, Mira
2015-01-01
A number of statistical methods for detecting gene-gene interactions have been developed in genetic association studies with binary traits. However, many phenotype measures are intrinsically quantitative and categorizing continuous traits may not always be straightforward and meaningful. Association of gene-gene interactions with an observed distribution of such phenotypes needs to be investigated directly without categorization. Information gain based on entropy measure has previously been successful in identifying genetic associations with binary traits. We extend the usefulness of this information gain by proposing a nonparametric evaluation method of conditional entropy of a quantitative phenotype associated with a given genotype. Hence, the information gain can be obtained for any phenotype distribution. Because any functional form, such as Gaussian, is not assumed for the entire distribution of a trait or a given genotype, this method is expected to be robust enough to be applied to any phenotypic association data. Here, we show its use to successfully identify the main effect, as well as the genetic interactions, associated with a quantitative trait. PMID:26339620
Yin, Chang-Xin; Jiang, Qian-Li; He, Han; Yu, Guo-Pan; Xu, Yue; Meng, Fan-Yi; Yang, Mo
2012-02-01
This study was aimed to establish a method for rapid detecting BK polyomavirus (BKV) and to investigate the feasibility and value used in leukemia patients undergoing hematopoietic stem cell transplantation. Primers were designed according to BKV gene sequence; the quantitative standards for BKV and a real-time fluorescent quantitative PCR for BKV were established. The BKV level in urine samples from 36 patients after hematopoietic stem cell transplantation were detected by established method. The results showed that the standard of reconstructed plasmid and real time fluorescent quantitative PCR method were successfully established, its good specificity, sensitivity and stability were confirmed by experiments. BKV was found in 55.56% of urine samples, and the BKV load in urine was 2.46 × 10(4) - 7.8 × 10(9) copy/ml. It is concluded that the establishment of real-time fluorescent quantitative PCR for BKV detection provides a method for early diagnosis of the patients with hemorrhagic cystitis after hematopoietic stem cell transplantation.
Quantitative learning strategies based on word networks
NASA Astrophysics Data System (ADS)
Zhao, Yue-Tian-Yi; Jia, Zi-Yang; Tang, Yong; Xiong, Jason Jie; Zhang, Yi-Cheng
2018-02-01
Learning English requires a considerable effort, but the way that vocabulary is introduced in textbooks is not optimized for learning efficiency. With the increasing population of English learners, learning process optimization will have significant impact and improvement towards English learning and teaching. The recent developments of big data analysis and complex network science provide additional opportunities to design and further investigate the strategies in English learning. In this paper, quantitative English learning strategies based on word network and word usage information are proposed. The strategies integrate the words frequency with topological structural information. By analyzing the influence of connected learned words, the learning weights for the unlearned words and dynamically updating of the network are studied and analyzed. The results suggest that quantitative strategies significantly improve learning efficiency while maintaining effectiveness. Especially, the optimized-weight-first strategy and segmented strategies outperform other strategies. The results provide opportunities for researchers and practitioners to reconsider the way of English teaching and designing vocabularies quantitatively by balancing the efficiency and learning costs based on the word network.
Quantitative Appearance Inspection for Film Coated Tablets.
Yoshino, Hiroyuki; Yamashita, Kazunari; Iwao, Yasunori; Noguchi, Shuji; Itai, Shigeru
2016-01-01
The decision criteria for the physical appearance of pharmaceutical products are subjective and qualitative means of evaluation that are based entirely on human interpretation. In this study, we have developed a comprehensive method for the quantitative analysis of the physical appearance of film coated tablets. Three different kinds of film coated tablets with considerable differences in their physical appearances were manufactured as models, and their surface roughness, contact angle, color measurements and physicochemical properties were investigated as potential characteristics for the quantitative analysis of their physical appearance. All of these characteristics were useful for the quantitative evaluation of the physical appearances of the tablets, and could potentially be used to establish decision criteria to assess the quality of tablets. In particular, the analysis of the surface roughness and film coating properties of the tablets by terahertz spectroscopy allowed for an effective evaluation of the tablets' properties. These results indicated the possibility of inspecting the appearance of tablets during the film coating process.
Measuring Plant Water Status: A Simple Method for Investigative Laboratories.
ERIC Educational Resources Information Center
Mansfield, Donald H.; Anderson, Jay E.
1980-01-01
Describes a method suitable for quantitative studies of plant water status conducted by high school or college students and the calculation of the relative water content (RWC) of a plant. Materials, methods, procedures, and results are discussed, with sample data figures provided. (CS)
Digital Immigrant Teacher Perceptions of an Extended Cyberhunt Strategy
ERIC Educational Resources Information Center
du Plessis, Andre; Webb, Paul
2012-01-01
This quantitative and qualitative interpretive exploratory case study investigates whether exposure to an Internet based "Extended Cyberhunt" strategy enables teachers to attain a set of outcomes similar to Prensky's "Essential 21st Century Skills" and the "Critical Outcomes of the South African National Curriculum…
Chemistry Teachers' Knowledge and Application of Models
ERIC Educational Resources Information Center
Wang, Zuhao; Chi, Shaohui; Hu, Kaiyan; Chen, Wenting
2014-01-01
Teachers' knowledge and application of model play an important role in students' development of modeling ability and scientific literacy. In this study, we investigated Chinese chemistry teachers' knowledge and application of models. Data were collected through test questionnaire and analyzed quantitatively and qualitatively. The result indicated…
Burnout and Job Satisfaction among Counselor Educators
ERIC Educational Resources Information Center
Sangganjanavanich, Varunee Faii; Balkin, Richard S.
2013-01-01
The relationship between burnout and job satisfaction among counselor educators was investigated. A total of 220 full-time counselor educators participated in this quantitative research study. Emotional exhaustion seemed to be the most significant predictor of burnout among counselor educators. Implications for counselor education and future…
The evolution of popular music: USA 1960-2010.
Mauch, Matthias; MacCallum, Robert M; Levy, Mark; Leroi, Armand M
2015-05-01
In modern societies, cultural change seems ceaseless. The flux of fashion is especially obvious for popular music. While much has been written about the origin and evolution of pop, most claims about its history are anecdotal rather than scientific in nature. To rectify this, we investigate the US Billboard Hot 100 between 1960 and 2010. Using music information retrieval and text-mining tools, we analyse the musical properties of approximately 17 000 recordings that appeared in the charts and demonstrate quantitative trends in their harmonic and timbral properties. We then use these properties to produce an audio-based classification of musical styles and study the evolution of musical diversity and disparity, testing, and rejecting, several classical theories of cultural change. Finally, we investigate whether pop musical evolution has been gradual or punctuated. We show that, although pop music has evolved continuously, it did so with particular rapidity during three stylistic 'revolutions' around 1964, 1983 and 1991. We conclude by discussing how our study points the way to a quantitative science of cultural change.
Singh, Gagandeep; Sharma, Anuradha; Kaur, Harpreet; Ishar, Mohan Paul S
2016-02-01
Regio- and stereoselective 1,3-dipolar cycloadditions of C-(chrom-4-one-3-yl)-N-phenylnitrones (N) with different mono-substituted, disubstituted, and cyclic dipolarophiles were carried out to obtain substituted N-phenyl-3'-(chrom-4-one-3-yl)-isoxazolidines (1-40). All the synthesized compounds were assayed for their in vitro antibacterial activity and display significant inhibitory potential; in particular, compound 32 exhibited good inhibitory activity against Salmonella typhymurium-1 & Salmonella typhymurium-2 with minimum inhibitory concentration value of 1.56 μg/mL and also showed good potential against methicillin-resistant Staphylococcus aureus with minimum inhibitory concentration 3.12 μg/mL. Quantitative structure activity relationship investigations with stepwise multiple linear regression analysis and docking simulation studies have been performed for validation of the observed antibacterial potential of the investigated compounds for determination of the most important parameters regulating antibacterial activities. © 2015 John Wiley & Sons A/S.
The use of mixed methods in studying a chronic illness.
Jason, Leonard A; Reed, Jordan
This article explores mixed methods approaches with an illness called Myalgic Encephalomyelitis (ME) and Chronic Fatigue Syndrome (CFS). Qualitative and Quantitative data were used to investigate the epidemiology of this illness, as well as explore attributions based on the name of the illness, and finally treatment approaches. In each of the domains within the ME and CFS research reviewed, our analyses were richer and our findings ultimately more impactful when we integrated qualitative and quantitative research methods. The use of a multiphase mixed methods research program provided our team unique vantage points for better understanding social and community issues involving this controversial chronic illness. Further, this approach allowed us to implement the insights gained through an advocacy lens to change policy, recommend and evaluate treatments, and amplify voices within the patient population. In this way, we believe that the practice of methodological pluralism is especially applicable and effective to the study of chronic illness, and believe other investigators will benefit from the use of these approaches with similar disenfranchised and unfairly treated populations.
Quantitative laser diagnostic and modeling study of C2 and CH chemistry in combustion.
Köhler, Markus; Brockhinke, Andreas; Braun-Unkhoff, Marina; Kohse-Höinghaus, Katharina
2010-04-15
Quantitative concentration measurements of CH and C(2) have been performed in laminar, premixed, flat flames of propene and cyclopentene with varying stoichiometry. A combination of cavity ring-down (CRD) spectroscopy and laser-induced fluorescence (LIF) was used to enable sensitive detection of these species with high spatial resolution. Previously, CH and C(2) chemistry had been studied, predominantly in methane flames, to understand potential correlations of their formation and consumption. For flames of larger hydrocarbon fuels, however, quantitative information on these small intermediates is scarce, especially under fuel-rich conditions. Also, the combustion chemistry of C(2) in particular has not been studied in detail, and although it has often been observed, its role in potential build-up reactions of higher hydrocarbon species is not well understood. The quantitative measurements performed here are the first to detect both species with good spatial resolution and high sensitivity in the same experiment in flames of C(3) and C(5) fuels. The experimental profiles were compared with results of combustion modeling to reveal details of the formation and consumption of these important combustion molecules, and the investigation was devoted to assist the further understanding of the role of C(2) and of its potential chemical interdependences with CH and other small radicals.
Clark, Michelle M; Blangero, John; Dyer, Thomas D; Sobel, Eric M; Sinsheimer, Janet S
2016-01-01
Maternal-offspring gene interactions, aka maternal-fetal genotype (MFG) incompatibilities, are neglected in complex diseases and quantitative trait studies. They are implicated in birth to adult onset diseases but there are limited ways to investigate their influence on quantitative traits. We present the quantitative-MFG (QMFG) test, a linear mixed model where maternal and offspring genotypes are fixed effects and residual correlations between family members are random effects. The QMFG handles families of any size, common or general scenarios of MFG incompatibility, and additional covariates. We develop likelihood ratio tests (LRTs) and rapid score tests and show they provide correct inference. In addition, the LRT's alternative model provides unbiased parameter estimates. We show that testing the association of SNPs by fitting a standard model, which only considers the offspring genotypes, has very low power or can lead to incorrect conclusions. We also show that offspring genetic effects are missed if the MFG modeling assumptions are too restrictive. With genome-wide association study data from the San Antonio Family Heart Study, we demonstrate that the QMFG score test is an effective and rapid screening tool. The QMFG test therefore has important potential to identify pathways of complex diseases for which the genetic etiology remains to be discovered. © 2015 John Wiley & Sons Ltd/University College London.
ERIC Educational Resources Information Center
Yousef, Darwish Abdulrahamn
2017-01-01
Purpose: This paper aims to investigate the impacts of teaching style, English language and communication and assessment methods on the academic performance of undergraduate business students in introductory quantitative courses such as Statistics for Business 1 and 2, Quantitative Methods for Business, Operations and Production Management and…
Does Homework Really Matter for College Students in Quantitatively-Based Courses?
ERIC Educational Resources Information Center
Young, Nichole; Dollman, Amanda; Angel, N. Faye
2016-01-01
This investigation was initiated by two students in an Advanced Computer Applications course. They sought to examine the influence of graded homework on final grades in quantitatively-based business courses. They were provided with data from three quantitatively-based core business courses over a period of five years for a total of 10 semesters of…
Solid-state NMR studies of proteins immobilized on inorganic surfaces
Shaw, Wendy J.
2014-10-29
Solid state NMR is the primary tool for studying the quantitative, site-specific structure, orientation, and dynamics of biomineralization proteins under biologically relevant conditions. Two calcium phosphate proteins, statherin and leucine rich amelogenin protein (LRAP), have been studied in depth and have different features, challenging our ability to extract design principles. More recent studies of the significantly larger full-length amelogenin represent a challenging but necessary step to ultimately investigate the full diversity of biomineralization proteins. Interactions of amino acids and silaffin peptide with silica are also being studied, along with qualitative studies of proteins interacting with calcium carbonate. Dipolar recoupling techniquesmore » have formed the core of the quantitative studies, yet, the need for isolated spin pairs makes this approach costly and time intensive. The use of multi-dimensional techniques is advancing, methodology which, despite its challenges with these difficult-to-study proteins, will continue to drive future advancements in this area.« less
The Impact of Web-Based Assessment and Practice on Students' Mathematics Learning Attitudes
ERIC Educational Resources Information Center
Nguyen, Diem M.; Hsieh, Yi-Chuan; Allen, G. Donald
2006-01-01
This study investigates the effects of web-based assessment and practice on improving middle school students' mathematics learning attitudes. With the use of an experimental design and a combination of quantitative and qualitative methods, the study compared and contrasted the attitude achievement of students, who used the web-based assessment and…
ERIC Educational Resources Information Center
Moore, Kristen E.
2014-01-01
This non-experimental quantitative study investigated two groups of adult students who received academic advising from full-time faculty advisors or full-time non-faculty advisors. Differences in student satisfaction on three measures related to advisor availability, accuracy and perceived support for student educational goals were studied based…
ERIC Educational Resources Information Center
Körük, Serdar; Öztürk, Abdülkadir; Kara, Ahmet
2016-01-01
This study aims to investigate the relationships between perceived parenting, parental attachment styles and psychological symptoms among Turkish university students and it also aims to find out which perceived parenting and parental attachment styles predict psychological symptoms which were measured. This study is a quantitative research and…
A Study of Readers Theater in Eighth Grade: Issues of Fluency, Comprehension, and Vocabulary
ERIC Educational Resources Information Center
Keehn, Susan; Harmon, Janis; Shoho, Alan
2008-01-01
This study investigated the impact of Readers Theater on eighth-grade students, the majority of whom were reading below grade level. Over six weeks of a short story unit, one class participated in Readers Theater. The comparison group of like-ability students received more traditional literary and vocabulary instruction. Quantitative measures…
Investigating the Effects of the Academy of Reading Program on Middle School Reading Achievement
ERIC Educational Resources Information Center
Myers, Brenda Gail
2016-01-01
Using a quantitative ex post facto causal comparative research design, this study analyzed the effects of the Academy of Reading software program on students' reading achievement. Tennessee Comprehensive Assessment Program (TCAP) reading scale scores of students in the fourth, fifth, and sixth grades from 2013-2014 were utilized in this study. The…
ERIC Educational Resources Information Center
Tafazoli, Dara; Gómez Parra, Mª Elena; Huertas Abril, Cristina A.
2018-01-01
The purpose of this study was to compare the attitude of Iranian and non-Iranian English language students' attitudes towards Computer-Assisted Language Learning (CALL). Furthermore, the relations of gender, education level, and age to their attitude are investigated. A convergent mixed methods design was used for analyzing both quantitative and…
Effects of an Adolescent Literacy Program on Ninth Grade Students Deficient in Literacy Skills
ERIC Educational Resources Information Center
Knuchel, Brian
2010-01-01
Research indicates that many adolescent students struggle with reading skills. Accordingly, this quantitative study attempted to address the problem of ninth-grade students entering high school deficient in literacy skills. The purpose of this non-experimental study was to investigate the effects a remedial reading program called Ramp-Up Literacy…
ERIC Educational Resources Information Center
White, Kiri; Boehm, Emilia; Chester, Andrea
2014-01-01
Peer review of teaching is a collegial process designed to help academics reflect on and improve their teaching practice. Considerable research supports the value of peer review of teaching. However, uptake of voluntary programs is typically low. Few studies have examined the predictors of engagement in voluntary peer review. This study surveyed…
ERIC Educational Resources Information Center
Su, Bude; Bonk, Curtis J.; Magjuka, Richard J.; Liu, Xiaojing; Lee, Seung-hee
2005-01-01
Though interaction is often billed as a significant component of successful online learning, empirical evidence of its importance as well as practical guidance or specific interaction techniques continue to be lacking. In response, this study utilizes both quantitative and qualitative data to investigate how instructors and students perceive the…
ERIC Educational Resources Information Center
Bai, Jieru
2016-01-01
A quantitative study was conducted to measure the acculturative stress of international students and investigate the predictors of acculturative stress. A total of 186 students participated in the survey. Results showed that 22.4% of the students in this study exceeded the normal stress level and might need counseling or psychological…
ERIC Educational Resources Information Center
Sha, Saliha L.
2012-01-01
This quantitative study investigated whether and to what extent the motivational and sociocultural factors affect female Asian American high school physics students' achievement, their intended major in college, and their planned career goals at work fields. A survey of 62 questions, extracted from subscales of AAMAS,STPQ and PSE, were…
Benefits of Higher Education in Mid-Life: A Life Course Agency Perspective
ERIC Educational Resources Information Center
Isopahkala-Bouret, Ulpukka
2017-01-01
The purpose of this study is to investigate the benefits of higher education in mid-life from the perspective of life course agency. Studies concerning the benefits of degree-oriented higher education have been mainly conducted using survey questionnaires and quantitative methods. In order to gain a more comprehensive picture, this qualitative…
Why It Won't Happen to Me: How Older Adolescents Make Personal Risk Assessments.
ERIC Educational Resources Information Center
Chapin, John; Chirico, JoAnn
This study sought to document optimistic bias among older adolescents in the context of numerous hazards. It was among the first studies to triangulate quantitative and qualitative measures to investigate how individuals make personal risk assessments within the optimistic bias literature. Results from a small-scale survey and follow-up interviews…
Not Accepted by the Family: "Being Difficult" or "Being Different"?
ERIC Educational Resources Information Center
Komter, Aafke; Voorpostel, Marieke; Pels, Trees
2011-01-01
Using data from the Netherlands Kinship Panel Study (NKPS) and combining a quantitative approach and a qualitative approach (N = 8,148 and n = 43, respectively), this study investigates the mechanisms associated with a lack of acceptance by one's family. From the total NKPS sample, 12.1% did not feel (entirely) accepted by their family. The…
The Use and Perception of English in Brazilian Magazine Advertisements
ERIC Educational Resources Information Center
Montes, Amanda Lira Gordenstein
2014-01-01
This study investigates the uses of English in advertising in Brazil and the attitudes of Brazilians towards the use of different difficulty levels of English in advertising. Using a two part, mixed-methods approach, drawing from quantitative and qualitative methods, I utilized a corpus study to examine English uses in Brazilian magazines and a…
ERIC Educational Resources Information Center
Lwin, Thawdar; Aslam, Sarfraz; Mukhale, Phoebe Naliaka
2017-01-01
This study was an investigation of the international students' perceptions of their learning environment in graduate programs at one normal university in China. The study used both quantitative and qualitative research methods. The sample comprised 91 international students, 51 Master and 40 doctoral from three schools: Education, Life Sciences…
A Musical Approach to Reading Fluency: An Experimental Study in First-Grade Classrooms
ERIC Educational Resources Information Center
Leguizamon, Daniel F.
2010-01-01
The purpose of this quantitative, quasi-experimental study was to investigate the relationship between Kodaly-based music instruction and reading fluency in first-grade classrooms. Reading fluency and overall reading achievement were measured for 109 participants at mid-point in the academic year pre- and post treatment. Tests were carried out to…
ERIC Educational Resources Information Center
Abeysekera, Indra
2011-01-01
This study examines three instructional methods (traditional, interactive, and group case-based study), and student opinions on their preference for learning financial accounting in large classes at a metropolitan university in Sri Lanka. It analyses the results of a survey questionnaire of students, using quantitative techniques to determine the…
ERIC Educational Resources Information Center
Abu-Tineh, Abdullah M.; Sadiq, Hissa M.
2018-01-01
The purpose of this study was to investigate the characteristics of effective professional development and effective models of professional development as perceived by school teachers in the State of Qatar. This study is quantitative in nature and was conducted using a survey methodology. Means, standard deviations, t-test, and one-way analysis of…
ERIC Educational Resources Information Center
Isaacs, Albert J.
2012-01-01
The purpose of this quantitative study was to investigate the relationships among the dimensions of resilience and the individual demographics of high school principals toward strengthening the leadership abilities of school principals. The study employs the survey method in its research design. Those surveyed included 68 high school principals,…
ERIC Educational Resources Information Center
Ojose, Bobby
2015-01-01
This study investigated proportional reasoning and the related concepts of decimal, percent, and ratio. In particular, the research focused on analyzing the gaps and understandings that grades 6, 7, and 8 students have and advanced factors for such gaps and understandings. The study employed a mixed method approach in which quantitative data was…
ERIC Educational Resources Information Center
Asmali, Mehmet; Bilki, Ufuk; Duban, Carina Adriana
2015-01-01
The present study attempts to offer a small-scale investigation of the willingness to communicate and its key antecedents, namely the self-perceived communication competence and the communication apprehension in Turkish and Romanian contexts. A total of 130 participants took part in this quantitative approach based study. The data suggested…
The Views of Turkish Science Teachers about Gender Equity within Science Education
ERIC Educational Resources Information Center
Idin, Sahin; Dönmez, Ismail
2017-01-01
The aim of this study was to investigate Turkish Science teachers' views about gender equity in the scope of science education. This study was conducted with the quantitative methodology. Within this scope, a 35-item 5-point Likert scale survey was developed to determine Science teachers' views concerning gender equity issues. 160 Turkish Science…
ERIC Educational Resources Information Center
Wilson, Gaye R.
2011-01-01
The purpose of this study was to investigate relationships between FLC membership and faculty trust in higher education colleagues and faculty trust in higher education administration in public and private universities in the United States. This quantitative study examines trust in colleagues and trust in administration in higher education, two…
The Role of Teaching Experience in Language Teachers' Perceptions of a Top-Down Curriculum Change
ERIC Educational Resources Information Center
Rahimi, Mehrak; Alavi, Jalil
2017-01-01
The current study aimed to investigate the role of teaching experience in language teachers' perceptions of a top-down curriculum change. One hundred twenty-seven language teachers who have been experiencing the change for three years participated in the study. Their perceptions of change were quantitatively assessed by perceptions of change…
ERIC Educational Resources Information Center
Culella, Nicole Anne
2017-01-01
The purpose of this quantitative study was to investigate teacher perception of technology integration in STEM and non-STEM classrooms of high school teachers of gifted and talented students and the relationship of those perceptions to actual technology use in their classrooms. This study measured teacher perception of technology integration…
ERIC Educational Resources Information Center
Moutsios-Rentzos, Andreas; Chaviaris, Petros; Kafoussi, Sonia
2015-01-01
In this quantitative study we investigated the primary school students' perceived parental involvement in mathematics with respect to different school socio-cultural identity as identified by the students' ethnicity. 493 students attending the two last grades of three primary schools participated in the study. The role of the students' grade and…
ERIC Educational Resources Information Center
Shibru, Sintayehu; Bibiso, Mesfin; Ousman, Kedir
2017-01-01
The purpose of this study was to investigate the relationship between middle level managers' quality of leadership and good governance, and organization performance of Wolaita Sodo University. The study employed descriptive survey method and used quantitative approach. College/school Deans, Department heads and Coordinators were source of data.…
ERIC Educational Resources Information Center
Clarke, Marie; Killeavy, Maureen; Moloney, Anne
2013-01-01
This study investigates the sources of mentors' knowledge about teaching. A mixed-method research design combining quantitative and qualitative data collection methods was used to examine this area. The findings of the study suggest that: mentors' knowledge about teaching is practice orientated and emerges from their professional experiences,…
Educators' Understanding of the Mediation Role in the Classroom
ERIC Educational Resources Information Center
Ngidi, D. P.
2012-01-01
This study investigated educators' understanding of the mediation role in the classroom. A quantitative research approach was used in a survey of a sample of 261 participants. To this end, a questionnaire was used for collecting data. The Chi-square test was used to analyse data and to test the hypotheses of the study. The findings indicated that…
ERIC Educational Resources Information Center
Lint, Anna H.
2013-01-01
This quantitative study evaluated and investigated the theoretical underpinnings of the Kember's (1995) student progress model that examines the direct or indirect effects of student persistence in online education by identifying the relationships between variables. The primary method of data collection in this study was a survey by exploring the…
ERIC Educational Resources Information Center
Sierra, Jade Simone
2013-01-01
This quantitative study investigated the predictive worthiness of the predictor variable indices--locus of control, self-efficacy, and gender identity--to ascertain if elevated levels of the predictors influence academic performance outcomes (individually as well as interactionally). The study theorized that students with increased levels of locus…
ERIC Educational Resources Information Center
Moore, Glenn M.
2012-01-01
Purpose and Method of Study. The primary purpose of this quantitative study was to analyze the relationship between school district expenditures and student academic achievement in 102 public elementary school districts in the state of Oklahoma. The secondary purpose was to investigate the relationship between school district expenditures and…
Perceptions and Barriers to ICT Use among English Teachers in Indonesia
ERIC Educational Resources Information Center
Muslem, Asnawi; Yusuf, Yunisrina Qismullah; Juliana, Rena
2018-01-01
The purpose of this research is to investigate English teachers' perception and challenges of the implementation of ICT in ELT classrooms. This study used mixed methods, qualitative and quantitative in nature. A purposive sampling technique was used to select the study subjects, who are 26 English teachers from 16 public senior high schools in…
ICT Teachers' Acceptance of "Scratch" as Algorithm Visualization Software
ERIC Educational Resources Information Center
Saltan, Fatih; Kara, Mehmet
2016-01-01
This study aims to investigate the acceptance of ICT teachers pertaining to the use of Scratch as an Algorithm Visualization (AV) software in terms of perceived ease of use and perceived usefulness. An embedded mixed method research design was used in the study, in which qualitative data were embedded in quantitative ones and used to explain the…
The Impact of Music on Student Achievement in the Third and Fifth Grade Math Curriculum
ERIC Educational Resources Information Center
Albright, Ruth E.
2012-01-01
Research indicates students who engage in music exhibit improved cognitive development. The quantitative study was conducted in a large suburban school district in Southeast Georgia. This study investigated the impact of music on student achievement when music is incorporated with the core academic subject of mathematics at the elementary level.…
Death and Dying Attitudes, Anxieties, and Fears of Certified Nursing Assistants: A Descriptive Study
ERIC Educational Resources Information Center
Hamilton, Josephine A.
2010-01-01
The critical role of Certified Nursing Assistants (CNAs) to help elderly nursing home residents' move through declining conditions or diseases to death is salient. It is important for CNAs and nursing home leaders to understand CNAs' attitudes, fears, and anxieties toward death and dying. The quantitative study investigated CNA's…
NASA Astrophysics Data System (ADS)
Moussaid, A.; Schosseler, F.; Munch, J. P.; Candau, S. J.
1993-04-01
The intensity scattered from polyacrylic acid and polymethacrylic acid solutions has been measured by small angle neutron scattering experiemnts. The influence of polymer concentration, ionization degree, temperature and salt content has been investigated. Results are in qualitative agreement with a model which predicts the existence of microphases in the unstable region of the phase diagram. Quantitative comparison with the theory is performed by fitting the theoretical structure factor to the experimental data. For a narrow range of ionizaiton degrees nearly quantitative agreement with the theory is found for the polyacrylic acide system.
Quantitative magneto-optical investigation of superconductor/ferromagnet hybrid structures
NASA Astrophysics Data System (ADS)
Shaw, G.; Brisbois, J.; Pinheiro, L. B. G. L.; Müller, J.; Blanco Alvarez, S.; Devillers, T.; Dempsey, N. M.; Scheerder, J. E.; Van de Vondel, J.; Melinte, S.; Vanderbemden, P.; Motta, M.; Ortiz, W. A.; Hasselbach, K.; Kramer, R. B. G.; Silhanek, A. V.
2018-02-01
We present a detailed quantitative magneto-optical imaging study of several superconductor/ferromagnet hybrid structures, including Nb deposited on top of thermomagnetically patterned NdFeB and permalloy/niobium with erasable and tailored magnetic landscapes imprinted in the permalloy layer. The magneto-optical imaging data are complemented with and compared to scanning Hall probe microscopy measurements. Comprehensive protocols have been developed for calibrating, testing, and converting Faraday rotation data to magnetic field maps. Applied to the acquired data, they reveal the comparatively weaker magnetic response of the superconductor from the background of larger fields and field gradients generated by the magnetic layer.
Quantitative sonoelastography for the in vivo assessment of skeletal muscle viscoelasticity
NASA Astrophysics Data System (ADS)
Hoyt, Kenneth; Kneezel, Timothy; Castaneda, Benjamin; Parker, Kevin J.
2008-08-01
A novel quantitative sonoelastography technique for assessing the viscoelastic properties of skeletal muscle tissue was developed. Slowly propagating shear wave interference patterns (termed crawling waves) were generated using a two-source configuration vibrating normal to the surface. Theoretical models predict crawling wave displacement fields, which were validated through phantom studies. In experiments, a viscoelastic model was fit to dispersive shear wave speed sonoelastographic data using nonlinear least-squares techniques to determine frequency-independent shear modulus and viscosity estimates. Shear modulus estimates derived using the viscoelastic model were in agreement with that obtained by mechanical testing on phantom samples. Preliminary sonoelastographic data acquired in healthy human skeletal muscles confirm that high-quality quantitative elasticity data can be acquired in vivo. Studies on relaxed muscle indicate discernible differences in both shear modulus and viscosity estimates between different skeletal muscle groups. Investigations into the dynamic viscoelastic properties of (healthy) human skeletal muscles revealed that voluntarily contracted muscles exhibit considerable increases in both shear modulus and viscosity estimates as compared to the relaxed state. Overall, preliminary results are encouraging and quantitative sonoelastography may prove clinically feasible for in vivo characterization of the dynamic viscoelastic properties of human skeletal muscle.
Using Qualitative Hazard Analysis to Guide Quantitative Safety Analysis
NASA Technical Reports Server (NTRS)
Shortle, J. F.; Allocco, M.
2005-01-01
Quantitative methods can be beneficial in many types of safety investigations. However, there are many difficulties in using quantitative m ethods. Far example, there may be little relevant data available. This paper proposes a framework for using quantitative hazard analysis to prioritize hazard scenarios most suitable for quantitative mziysis. The framework first categorizes hazard scenarios by severity and likelihood. We then propose another metric "modeling difficulty" that desc ribes the complexity in modeling a given hazard scenario quantitatively. The combined metrics of severity, likelihood, and modeling difficu lty help to prioritize hazard scenarios for which quantitative analys is should be applied. We have applied this methodology to proposed concepts of operations for reduced wake separation for airplane operatio ns at closely spaced parallel runways.
Critical behavior of subcellular density organization during neutrophil activation and migration.
Baker-Groberg, Sandra M; Phillips, Kevin G; Healy, Laura D; Itakura, Asako; Porter, Juliana E; Newton, Paul K; Nan, Xiaolin; McCarty, Owen J T
2015-12-01
Physical theories of active matter continue to provide a quantitative understanding of dynamic cellular phenomena, including cell locomotion. Although various investigations of the rheology of cells have identified important viscoelastic and traction force parameters for use in these theoretical approaches, a key variable has remained elusive both in theoretical and experimental approaches: the spatiotemporal behavior of the subcellular density. The evolution of the subcellular density has been qualitatively observed for decades as it provides the source of image contrast in label-free imaging modalities (e.g., differential interference contrast, phase contrast) used to investigate cellular specimens. While these modalities directly visualize cell structure, they do not provide quantitative access to the structures being visualized. We present an established quantitative imaging approach, non-interferometric quantitative phase microscopy, to elucidate the subcellular density dynamics in neutrophils undergoing chemokinesis following uniform bacterial peptide stimulation. Through this approach, we identify a power law dependence of the neutrophil mean density on time with a critical point, suggesting a critical density is required for motility on 2D substrates. Next we elucidate a continuum law relating mean cell density, area, and total mass that is conserved during neutrophil polarization and migration. Together, our approach and quantitative findings will enable investigators to define the physics coupling cytoskeletal dynamics with subcellular density dynamics during cell migration.
Critical behavior of subcellular density organization during neutrophil activation and migration
Baker-Groberg, Sandra M.; Phillips, Kevin G.; Healy, Laura D.; Itakura, Asako; Porter, Juliana E.; Newton, Paul K.; Nan, Xiaolin; McCarty, Owen J.T.
2015-01-01
Physical theories of active matter continue to provide a quantitative understanding of dynamic cellular phenomena, including cell locomotion. Although various investigations of the rheology of cells have identified important viscoelastic and traction force parameters for use in these theoretical approaches, a key variable has remained elusive both in theoretical and experimental approaches: the spatiotemporal behavior of the subcellular density. The evolution of the subcellular density has been qualitatively observed for decades as it provides the source of image contrast in label-free imaging modalities (e.g., differential interference contrast, phase contrast) used to investigate cellular specimens. While these modalities directly visualize cell structure, they do not provide quantitative access to the structures being visualized. We present an established quantitative imaging approach, non-interferometric quantitative phase microscopy, to elucidate the subcellular density dynamics in neutrophils undergoing chemokinesis following uniform bacterial peptide stimulation. Through this approach, we identify a power law dependence of the neutrophil mean density on time with a critical point, suggesting a critical density is required for motility on 2D substrates. Next we elucidate a continuum law relating mean cell density, area, and total mass that is conserved during neutrophil polarization and migration. Together, our approach and quantitative findings will enable investigators to define the physics coupling cytoskeletal dynamics with subcellular density dynamics during cell migration. PMID:26640599
Jungmann, Pia M.; Baum, Thomas; Bauer, Jan S.; Karampinos, Dimitrios C.; Link, Thomas M.; Li, Xiaojuan; Trattnig, Siegfried; Rummeny, Ernst J.; Woertler, Klaus; Welsch, Goetz H.
2014-01-01
Background. New quantitative magnetic resonance imaging (MRI) techniques are increasingly applied as outcome measures after cartilage repair. Objective. To review the current literature on the use of quantitative MRI biomarkers for evaluation of cartilage repair at the knee and ankle. Methods. Using PubMed literature research, studies on biochemical, quantitative MR imaging of cartilage repair were identified and reviewed. Results. Quantitative MR biomarkers detect early degeneration of articular cartilage, mainly represented by an increasing water content, collagen disruption, and proteoglycan loss. Recently, feasibility of biochemical MR imaging of cartilage repair tissue and surrounding cartilage was demonstrated. Ultrastructural properties of the tissue after different repair procedures resulted in differences in imaging characteristics. T2 mapping, T1rho mapping, delayed gadolinium-enhanced MRI of cartilage (dGEMRIC), and diffusion weighted imaging (DWI) are applicable on most clinical 1.5 T and 3 T MR scanners. Currently, a standard of reference is difficult to define and knowledge is limited concerning correlation of clinical and MR findings. The lack of histological correlations complicates the identification of the exact tissue composition. Conclusions. A multimodal approach combining several quantitative MRI techniques in addition to morphological and clinical evaluation might be promising. Further investigations are required to demonstrate the potential for outcome evaluation after cartilage repair. PMID:24877139
Nicolotti, Luca; Cordero, Chiara; Cagliero, Cecilia; Liberto, Erica; Sgorbini, Barbara; Rubiolo, Patrizia; Bicchi, Carlo
2013-10-10
The study proposes an investigation strategy that simultaneously provides detailed profiling and quantitative fingerprinting of food volatiles, through a "comprehensive" analytical platform that includes sample preparation by Headspace Solid Phase Microextraction (HS-SPME), separation by two-dimensional comprehensive gas chromatography coupled with mass spectrometry detection (GC×GC-MS) and data processing using advanced fingerprinting approaches. Experiments were carried out on roasted hazelnuts and on Gianduja pastes (sugar, vegetable oil, hazelnuts, cocoa, nonfat dried milk, vanilla flavorings) and demonstrated that the information potential of each analysis can better be exploited if suitable quantitation methods are applied. Quantitation approaches through Multiple Headspace Extraction and Standard Addition were compared in terms of performance parameters (linearity, precision, accuracy, Limit of Detection and Limit of Quantitation) under headspace linearity conditions. The results on 19 key analytes, potent odorants, and technological markers, and more than 300 fingerprint components, were used for further processing to obtain information concerning the effect of the matrix on volatile release, and to produce an informative chemical blueprint for use in sensomics and flavoromics. The importance of quantitation approaches in headspace analysis of solid matrices of complex composition, and the advantages of MHE, are also critically discussed. Copyright © 2013 Elsevier B.V. All rights reserved.
Defining Success in Adult Basic Education Settings: Multiple Stakeholders, Multiple Perspectives
Tighe, Elizabeth L.; Barnes, Adrienne E.; Connor, Carol M.; Steadman, Sharilyn C.
2015-01-01
This study employed quantitative and qualitative research approaches to investigate what constitutes “success” in Adult Basic Education (ABE) programs from the perspectives of multiple educational stakeholders: the state funding agency, the teachers, and the students. Success was defined in multiple ways. In the quantitative section of the study, we computed classroom value-added scores (used as a metric of the state’s definition of success) to identify more and less effective ABE classrooms in two Florida counties. In the qualitative section of the study, we observed and conducted interviews with teachers and students in the selected classrooms to investigate how these stakeholders defined success in ABE. Iterative consideration of the qualitative data revealed three principal markers of success: (a) instructional strategies and teacher-student interactions; (b) views on standardized testing; and (c) student motivational factors. In general, classrooms with higher value-added scores were characterized by multiple instructional approaches, positive and collaborative teacher-student interactions, and students engaging in goal setting and citing motivational factors such as family and personal fulfillment. The implications for ABE programs are discussed. PMID:26279590
Saykin, Andrew J.; Shen, Li; Foroud, Tatiana M.; Potkin, Steven G.; Swaminathan, Shanker; Kim, Sungeun; Risacher, Shannon L.; Nho, Kwangsik; Huentelman, Matthew J.; Craig, David W.; Thompson, Paul M.; Stein, Jason L.; Moore, Jason H.; Farrer, Lindsay A.; Green, Robert C.; Bertram, Lars; Jack, Clifford R.; Weiner, Michael W.
2010-01-01
The role of the Alzheimer’s Disease Neuroimaging Initiative Genetics Core is to facilitate the investigation of genetic influences on disease onset and trajectory as reflected in structural, functional, and molecular imaging changes; fluid biomarkers; and cognitive status. Major goals include (1) blood sample processing, genotyping, and dissemination, (2) genome-wide association studies (GWAS) of longitudinal phenotypic data, and (3) providing a central resource, point of contact and planning group for genetics within Alzheimer’s Disease Neuroimaging Initiative. Genome-wide array data have been publicly released and updated, and several neuroimaging GWAS have recently been reported examining baseline magnetic resonance imaging measures as quantitative phenotypes. Other preliminary investigations include copy number variation in mild cognitive impairment and Alzheimer’s disease and GWAS of baseline cerebrospinal fluid biomarkers and longitudinal changes on magnetic resonance imaging. Blood collection for RNA studies is a new direction. Genetic studies of longitudinal phenotypes hold promise for elucidating disease mechanisms and risk, development of therapeutic strategies, and refining selection criteria for clinical trials. PMID:20451875
NASA Technical Reports Server (NTRS)
Lada, Charles J.
2004-01-01
This grant funds a research program to use infrared extinction measurements to probe the detailed structure of dark molecular cloud cores and investigate the physical conditions which give rise to star and planet formation. The goals of this program are to acquire, reduce and analyze deep infrared and molecular-line observations of a carefully selected sample of nearby dark clouds in order to determine the detailed initial conditions for star formation from quantitative measurements of the internal structure of starless cloud cores and to quantitatively investigate the evolution of such structure through the star and planet formation process.
Budke, C; Heggemann, C; Koch, M; Sewald, N; Koop, T
2009-03-05
The Ostwald ripening of polycrystalline ice in aqueous sucrose solutions was investigated experimentally. The kinetics of this ice recrystallization process was studied at temperatures between -6 and -10 degrees C and varying ice volume fractions. Using the theory of Lifshitz, Slyozov, and Wagner (LSW), the diffusion-limited rate constant for ice recrystallization was determined. Also, the effects of synthetic analogues of natural antifreeze glycoproteins (AFGP) were studied. These analogues synAFGPmi (i = 3-5) contained monosaccharide side groups instead of disaccharide side groups that occur in natural AFGP. In order to account for the inhibition effect of the synAFGPmi, we have modified classical LSW theory, allowing for the derivation of inhibition rate constants. It was found that the investigated synAFGPmi inhibit ice recrystallization at concentrations down to approximately 3 microg mL(-1) or, equivalently, approximately 1 micromol L(-1) for the largest synAFGPmi investigated: synAFGPm5. Hence, our new method is capable of quantitatively assessing the efficiency of very similar AFGP with a sensitivity that is at least 2 orders of magnitude larger than that typical for quantitative thermal hysteresis measurements.
NASA Astrophysics Data System (ADS)
Edmiston, John Kearney
This work explores the field of continuum plasticity from two fronts. On the theory side, we establish a complete specification of a phenomenological theory of plasticity for single crystals. The model serves as an alternative to the popular crystal plasticity formulation. Such a model has been previously proposed in the literature; the new contribution made here is the constitutive framework and resulting simulations. We calibrate the model to available data and use a simple numerical method to explore resulting predictions in plane strain boundary value problems. Results show promise for further investigation of the plasticity model. Conveniently, this theory comes with a corresponding experimental tool in X-ray diffraction. Recent advances in hardware technology at synchrotron sources have led to an increased use of the technique for studies of plasticity in the bulk of materials. The method has been successful in qualitative observations of material behavior, but its use in quantitative studies seeking to extract material properties is open for investigation. Therefore in the second component of the thesis several contributions are made to synchrotron X-ray diffraction experiments, in terms of method development as well as the quantitative reporting of constitutive parameters. In the area of method development, analytical tools are developed to determine the available precision of this type of experiment—a crucial aspect to determine if the method is to be used for quantitative studies. We also extract kinematic information relating to intragranular inhomogeneity which is not accessible with traditional methods of data analysis. In the area of constitutive parameter identification, we use the method to extract parameters corresponding to the proposed formulation of plasticity for a titanium alloy (HCP) which is continuously sampled by X-ray diffraction during uniaxial extension. These results and the lessons learned from the efforts constitute early reporting of the quantitative profitability of undertaking such a line of experimentation for the study of plastic deformation processes.
NASA Astrophysics Data System (ADS)
Melelli, Laura; Liucci, Luisa; Vergari, Francesca; Ciccacci, Sirio; Del Monte, Maurizio
2014-05-01
Drainage basins are primary landscape units for geomorphological investigations. Both hillslopes and river drainage system are fundamental components in drainage basins analysis. As other geomorphological systems, also the drainage basins aim to an equilibrium condition where the sequence of erosion, transport and sedimentation approach to a condition of minimum energy effort. This state is revealed by a typical geometry of landforms and of drainage net. Several morphometric indexes can measure how much a drainage basin is far from the theoretical equilibrium configuration, revealing possible external disarray. In active tectonic areas, the drainage basins have a primary importance in order to highlight style, amount and rate of tectonic impulses, and morphometric indexes allow to estimate the tectonic activity classes of different sectors in a study area. Moreover, drainage rivers are characterized by a self-similarity structure; this promotes the use of fractals theory to investigate the system. In this study, fractals techniques are employed together with quantitative geomorphological analysis to study the Upper Tiber Valley (UTV), a tectonic intermontane basin located in northern Apennines (Umbria, central Italy). The area is the result of different tectonic phases. From Late Pliocene until present time the UTV is strongly controlled by a regional uplift and by an extensional phase with different sets of normal faults playing a fundamental role in basin morphology. Thirty-four basins are taken into account for the quantitative analysis, twenty on the left side of the basin, the others on the right side. Using fractals dimension of drainage networks, Horton's laws results, concavity and steepness indexes, and hypsometric curves, this study aims to obtain an evolutionary model of the UTV, where the uplift is compared to local subsidence induced by normal fault activity. The results highlight a well defined difference between western and eastern tributary basins, suggesting a greater disequilibrium in the last ones. The quantitative analysis points out the segments of the basin boundaries where the fault activity is more efficient and the resulting geomorphological implications.
Spalenza, Veronica; Girolami, Flavia; Bevilacqua, Claudia; Riondato, Fulvio; Rasero, Roberto; Nebbia, Carlo; Sacchi, Paola; Martin, Patrice
2011-09-01
Gene expression studies in blood cells, particularly lymphocytes, are useful for monitoring potential exposure to toxicants or environmental pollutants in humans and livestock species. Quantitative PCR is the method of choice for obtaining accurate quantification of mRNA transcripts although variations in the amount of starting material, enzymatic efficiency, and the presence of inhibitors can lead to evaluation errors. As a result, normalization of data is of crucial importance. The most common approach is the use of endogenous reference genes as an internal control, whose expression should ideally not vary among individuals and under different experimental conditions. The accurate selection of reference genes is therefore an important step in interpreting quantitative PCR studies. Since no systematic investigation in bovine lymphocytes has been performed, the aim of the present study was to assess the expression stability of seven candidate reference genes in circulating lymphocytes collected from 15 dairy cows. Following the characterization by flow cytometric analysis of the cell populations obtained from blood through a density gradient procedure, three popular softwares were used to evaluate the gene expression data. The results showed that two genes are sufficient for normalization of quantitative PCR studies in cattle lymphocytes and that YWAHZ, S24 and PPIA are the most stable genes. Copyright © 2010 Elsevier Ltd. All rights reserved.
NASA Astrophysics Data System (ADS)
Zargari, Abolfazl; Du, Yue; Thai, Theresa C.; Gunderson, Camille C.; Moore, Kathleen; Mannel, Robert S.; Liu, Hong; Zheng, Bin; Qiu, Yuchen
2018-02-01
The objective of this study is to investigate the performance of global and local features to better estimate the characteristics of highly heterogeneous metastatic tumours, for accurately predicting the treatment effectiveness of the advanced stage ovarian cancer patients. In order to achieve this , a quantitative image analysis scheme was developed to estimate a total of 103 features from three different groups including shape and density, Wavelet, and Gray Level Difference Method (GLDM) features. Shape and density features are global features, which are directly applied on the entire target image; wavelet and GLDM features are local features, which are applied on the divided blocks of the target image. To assess the performance, the new scheme was applied on a retrospective dataset containing 120 recurrent and high grade ovary cancer patients. The results indicate that the three best performed features are skewness, root-mean-square (rms) and mean of local GLDM texture, indicating the importance of integrating local features. In addition, the averaged predicting performance are comparable among the three different categories. This investigation concluded that the local features contains at least as copious tumour heterogeneity information as the global features, which may be meaningful on improving the predicting performance of the quantitative image markers for the diagnosis and prognosis of ovary cancer patients.
Schwendener, Nicole; Jackowski, Christian; Persson, Anders; Warntjes, Marcel J; Schuster, Frederick; Riva, Fabiano; Zech, Wolf-Dieter
2017-01-01
Recently, quantitative MR sequences have started being used in post-mortem imaging. The goal of the present study was to evaluate if early acute and following age stages of myocardial infarction can be detected and discerned by quantitative 1.5T post-mortem cardiac magnetic resonance (PMCMR) based on quantitative T1, T2 and PD values. In 80 deceased individuals (25 female, 55 male), a cardiac MR quantification sequence was performed prior to cardiac dissection at autopsy in a prospective study. Focal myocardial signal alterations detected in synthetically generated MR images were MR quantified for their T1, T2 and PD values. The locations of signal alteration measurements in PMCMR were targeted at autopsy heart dissection and cardiac tissue specimens were taken for histologic examinations. Quantified signal alterations in PMCMR were correlated to their according histologic age stage of myocardial infarction. In PMCMR seventy-three focal myocardial signal alterations were detected in 49 of 80 investigated hearts. These signal alterations were diagnosed histologically as early acute (n=39), acute (n=14), subacute (n=10) and chronic (n=10) age stages of myocardial infarction. Statistical analysis revealed that based on their quantitative T1, T2 and PD values, a significant difference between all defined age groups of myocardial infarction can be determined. It can be concluded that quantitative 1.5T PMCMR quantification based on quantitative T1, T2 and PD values is feasible for characterization and differentiation of early acute and following age stages of myocardial infarction. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.
2014-01-01
Background Inflammatory mediators can serve as biomarkers for the monitoring of the disease progression or prognosis in many conditions. In the present study we introduce an adaptation of a membrane-based technique in which the level of up to 40 cytokines and chemokines can be determined in both human and rodent blood in a semi-quantitative way. The planar assay was modified using the LI-COR (R) detection system (fluorescence based) rather than chemiluminescence and semi-quantitative outcomes were achieved by normalizing the outcomes using the automated exposure settings of the Odyssey readout device. The results were compared to the gold standard assay, namely ELISA. Results The improved planar assay allowed the detection of a considerably higher number of analytes (n = 30 and n = 5 for fluorescent and chemiluminescent detection, respectively). The improved planar method showed high sensitivity up to 17 pg/ml and a linear correlation of the normalized fluorescence intensity with the results from the ELISA (r = 0.91). Conclusions The results show that the membrane-based technique is a semi-quantitative assay that correlates satisfactorily to the gold standard when enhanced by the use of fluorescence and subsequent semi-quantitative analysis. This promising technique can be used to investigate inflammatory profiles in multiple conditions, particularly in studies with constraints in sample sizes and/or budget. PMID:25022797
Noge, Sachiko; Ohishi, Tatsuo; Yoshida, Takuya; Kumagai, Hiromichi
2017-01-01
[Purpose] Locomotive syndrome (LS) is a condition by which older people may require care service because of problems with locomotive organs. This study examined whether the loco-check, a 7-item questionnaire, is useful for quantitatively assessing the severity of LS. [Subjects and Methods] Seventy-one community dwelling Japanese females aged 64–96 years (81.7 ± 8.0 years) participated in this study. The associations of the loco-check with thigh muscle mass measured by X-ray CT, physical performance, nutritional status, and quality of life (QOL) were investigated. [Results] The results showed that the number of times that “yes” was selected in the loco-check was significantly correlated with thigh muscle mass, major measures of physical performance, nutritional status, and QOL. This number was also significantly larger in the participants experiencing falling, fracture, and lumbar pain than in those without these episodes. [Conclusion] These results suggest that the loco-check might be useful for quantitatively evaluating LS. PMID:28932003
Knowles, D.B.
1955-01-01
The objective of the Ground Water Branch is to evaluate the occurrence, availability, and quality of ground water. The science of ground-water hydrology is applied toward attaining that goal. Although many ground-water investigations are of a qualitative nature, quantitative studies are necessarily an integral component of the complete evaluation of occurrence and availability. The worth of an aquifer as a fully developed source of water depends largely on two inherent characteristics: its ability to store, and its ability to transmit water. Furthermore, quantitative knowledge of these characteristics facilitates measurement of hydrologic entities such as recharge, leakage, evapotranspiration, etc. It is recognized that these two characteristics, referred to as the coefficients of storage and transmissibility, generally provide the very foundation on which quantitative studies are constructed. Within the science of ground-water hydrology, ground-water hydraulics methods are applied to determine these constats from field data.
Feedback Effects of Teaching Quality Assessment: Macro and Micro Evidence
ERIC Educational Resources Information Center
Bianchini, Stefano
2014-01-01
This study investigates the feedback effects of teaching quality assessment. Previous literature looked separately at the evolution of individual and aggregate scores to understand whether instructors and university performance depends on its past evaluation. I propose a new quantitative-based methodology, combining statistical distributions and…
Elementary Teachers' Mathematical Knowledge for Teaching Prerequisite Algebra Concepts
ERIC Educational Resources Information Center
Welder, Rachael M.; Simonsen, Linda M.
2011-01-01
The current study investigated the effects of an undergraduate mathematics content course for pre-service elementary teachers. The participants' content knowledge was quantitatively measured using an instrument comprised of items from the Mathematical Knowledge for Teaching Measures (Hill, Schilling, & Ball, 2004). Using a one-group…
Gender Differences in Resilience of Academic Deans
ERIC Educational Resources Information Center
Isaacs, Albert J.
2014-01-01
The purpose of this investigation was to determine the difference in the levels of resilience characteristics between male and female deans within a state university system. Resilience is the ability to operate in a changing environment while consistently maintaining one's effectiveness. This quantitative study utilized the survey, Personal…
Self-identity Changes and English Learning among Chinese Undergraduates.
ERIC Educational Resources Information Center
Yihong, Gao; Ying, Cheng; Yuan, Zhao; Yan, Zhou
2005-01-01
This quantitative study investigated Chinese college students' self-identity changes associated with English learning. The subjects were 2,278 undergraduates from 30 universities, obtained from a stratified sampling. Based on existing literature of bilinguals identities, the self-designed questionnaire defined six categories of self-identity…
Response to Intervention: Research and Practice
ERIC Educational Resources Information Center
Hall, Carol; Mahoney, Jamie
2013-01-01
Response to Intervention (RTI) is a service model designed to meet the learning needs of students prior to diagnosis and placement in special education settings. Results of a quantitative quasi-experimental research study to investigate the relationship between the RTI plan and self-reported implementation practices among general education…
Personal Growth Groups: Measuring Outcome and Evaluating Impact
ERIC Educational Resources Information Center
Young, Tabitha L.; Reysen, Rebekah; Eskridge, Talunja; Ohrt, Jonathan H.
2013-01-01
Although researchers speculate counselor-trainees who participate in personal growth groups as part of their course curriculum experience essential group processes and personal growth, there is a lack of empirical evidence supporting this claim. This quantitative study investigates counselor-trainee's perceptions of the therapeutic, developmental,…
Motivation to Speak English: A Self-Determination Theory Perspective
ERIC Educational Resources Information Center
Dincer, Ali; Yesilyurt, Savas
2017-01-01
Based on a modern motivation theory of learning, self-determination theory (SDT), this study aimed to investigate the relationships between English as a foreign language (EFL) learners' motivation to speak, autonomous regulation, autonomy support from teachers, and classroom engagement, with both quantitative and qualitative approaches. The…
USE OF SHALLOW WATER HABITATS BY ECONOMICALLY VALUABLE FISHES AND CRUSTACEANS
I investigated nekton use of bay-exposed fringing salt marsh habitats at the Goodwin Islands NERRS location (York River, Virginia) in two separate studies. In a 1995 project, depositional-edged salt marshes and the adjacent non-vegetated habitats were sampled with quantitative 1....
Examining Practical Relevance of the Coursework of Doctoral Leadership Programs
ERIC Educational Resources Information Center
Li, Jinyi; Friedel, Janice; Rusche, Philip
2011-01-01
This quantitative study investigated the extent to which doctoral leadership programs are practically relevant. Results revealed that community college leaders and leadership program faculty did not differ significantly on the importance ratings on the American Association of Community Colleges (AACC) competencies. The subsequent analysis,…
Principals' Attitudes toward the Inclusion of Students with Disabilities
ERIC Educational Resources Information Center
Stith, Angelnet L.
2013-01-01
The quantitative correlation study investigated 50 Virginia's elementary principals' attitudes toward the inclusion of students with disabilities and principals' training, experience, placement decision, and state assessment decision in special education. The data was collected using the modified version of Principal and Inclusion Survey tool.…
How Effective Are Indiana's New Principals? Implications for Preparation and Practice
ERIC Educational Resources Information Center
Boyland, Lori G.; Lehman, Lynn E.; Sriver, Shawn K.
2015-01-01
This study investigates the performance of Indiana's new principals per the Educational Leadership Constituent Council (ELCC) and the Indiana Content Standards for building-level leader preparation. Using quantitative survey methodology, information was collected from Indiana superintendents regarding the effectiveness of principals who had…
Teacher Contract Non-Renewal: Midwest, Rocky Mountains, and Southeast
ERIC Educational Resources Information Center
Nixon, Andy; Dam, Margaret; Packard, Abbot L.
2012-01-01
This quantitative study investigated reasons that school principals recommend non-renewal of probationary teachers' contracts. Principal survey results from three regions of the US (Midwest, Rocky Mountains, & Southeast) were analyzed using the Kruskal-Wallis and Mann-Whitney U statistical procedures, while significance was tested applying a…
Mixed-Methods Research Methodologies
ERIC Educational Resources Information Center
Terrell, Steven R.
2012-01-01
Mixed-Method studies have emerged from the paradigm wars between qualitative and quantitative research approaches to become a widely used mode of inquiry. Depending on choices made across four dimensions, mixed-methods can provide an investigator with many design choices which involve a range of sequential and concurrent strategies. Defining…
Molenaar, Remco J; Khurshed, Mohammed; Hira, Vashendriya V V; Van Noorden, Cornelis J F
2018-05-26
Altered cellular metabolism is a hallmark of many diseases, including cancer, cardiovascular diseases and infection. The metabolic motor units of cells are enzymes and their activity is heavily regulated at many levels, including the transcriptional, mRNA stability, translational, post-translational and functional level. This complex regulation means that conventional quantitative or imaging assays, such as quantitative mRNA experiments, Western Blots and immunohistochemistry, yield incomplete information regarding the ultimate activity of enzymes, their function and/or their subcellular localization. Quantitative enzyme cytochemistry and histochemistry (i.e., metabolic mapping) show in-depth information on in situ enzymatic activity and its kinetics, function and subcellular localization in an almost true-to-nature situation. We describe a protocol to detect the activity of dehydrogenases, which are enzymes that perform redox reactions to reduce cofactors such as NAD(P) + and FAD. Cells and tissue sections are incubated in a medium that is specific for the enzymatic activity of one dehydrogenase. Subsequently, the dehydrogenase that is the subject of investigation performs its enzymatic activity in its subcellular site. In a chemical reaction with the reaction medium, this ultimately generates blue-colored formazan at the site of the dehydrogenase's activity. The formazan's absorbance is therefore a direct measure of the dehydrogenase's activity and can be quantified using monochromatic light microscopy and image analysis. The quantitative aspect of this protocol enables researchers to draw statistical conclusions from these assays. Besides observational studies, this technique can be used for inhibition studies of specific enzymes. In this context, studies benefit from the true-to-nature advantages of metabolic mapping, giving in situ results that may be physiologically more relevant than in vitro enzyme inhibition studies. In all, metabolic mapping is an indispensable technique to study metabolism at the cellular or tissue level. The technique is easy to adopt, provides in-depth, comprehensive and integrated metabolic information and enables rapid quantitative analysis.
Petriwskyj, Andrea; Gibson, Alexandra; Parker, Deborah; Banks, Susan; Andrews, Sharon; Robinson, Andrew
2014-06-01
Ensuring older adults' involvement in their care is accepted as good practice and is vital, particularly for people with dementia, whose care and treatment needs change considerably over the course of the illness. However, involving family members in decision making on people's behalf is still practically difficult for staff and family. The aim of this review was to identify and appraise the existing quantitative evidence about family involvement in decision making for people with dementia living in residential aged care. The present Joanna Briggs Institute (JBI) metasynthesis assessed studies that investigated involvement of family members in decision making for people with dementia in residential aged care settings. While quantitative and qualitative studies were included in the review, this paper presents the quantitative findings. A comprehensive search of 15 electronic databases was performed. The search was limited to papers published in English, from 1990 to 2013. Twenty-six studies were identified as being relevant; 10 were quantitative, with 1 mixed method study. Two independent reviewers assessed the studies for methodological validity and extracted the data using the JBI Meta Analysis of Statistics Assessment and Review Instrument (JBI-MAStARI). The findings were synthesized and presented in narrative form. The findings related to decisions encountered and made by family surrogates, variables associated with decisions, surrogates' perceptions of, and preferences for, their roles, as well as outcomes for people with dementia and their families. The results identified patterns within, and variables associated with, surrogate decision making, all of which highlight the complexity and variation regarding family involvement. Attention needs to be paid to supporting family members in decision making in collaboration with staff.
Modeling conflict : research methods, quantitative modeling, and lessons learned.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Rexroth, Paul E.; Malczynski, Leonard A.; Hendrickson, Gerald A.
2004-09-01
This study investigates the factors that lead countries into conflict. Specifically, political, social and economic factors may offer insight as to how prone a country (or set of countries) may be for inter-country or intra-country conflict. Largely methodological in scope, this study examines the literature for quantitative models that address or attempt to model conflict both in the past, and for future insight. The analysis concentrates specifically on the system dynamics paradigm, not the political science mainstream approaches of econometrics and game theory. The application of this paradigm builds upon the most sophisticated attempt at modeling conflict as a resultmore » of system level interactions. This study presents the modeling efforts built on limited data and working literature paradigms, and recommendations for future attempts at modeling conflict.« less
Quantitative Measures of Swallowing Deficits in Patients With Parkinson's Disease.
Ellerston, Julia K; Heller, Amanda C; Houtz, Daniel R; Kendall, Katherine A
2016-05-01
Dysphagia and associated aspiration pneumonia are commonly reported sequelae of Parkinson's disease (PD). Previous studies of swallowing in patients with PD have described prolonged pharyngeal transit time, delayed onset of pharyngeal transit, cricopharyngeal (CP) achalasia, reduced pharyngeal constriction, and slowed hyolaryngeal elevation. These studies were completed using inconsistent evaluation methodology, reliance on qualitative analysis, and a lack of a large control group, resulting in concerns regarding diagnostic precision. The purpose of this study was to investigate swallowing function in patients with PD using a norm-referenced, quantitative approach. This retrospective study includes 34 patients with a diagnosis of PD referred to a multidisciplinary voice and swallowing clinic. Modified barium swallow studies were performed using quantitative measures of pharyngeal transit time, hyoid displacement, CP sphincter opening, area of the pharynx at maximal constriction, and timing of laryngeal vestibule closure relative to bolus arrival at the CP sphincter. Reduced pharyngeal constriction was found in 30.4%, and a delay in airway closure relative to arrival of the bolus at the CP sphincter was the most common abnormality, present in 62% of patients. Previously reported findings of prolonged pharyngeal transit, poor hyoid elevation, and CP achalasia were not identified as prominent features. © The Author(s) 2015.
Burger, Stefan; Fraunholz, Thomas; Leirer, Christian; Hoppe, Ronald H W; Wixforth, Achim; Peter, Malte A; Franke, Thomas
2013-06-25
Phase decomposition in lipid membranes has been the subject of numerous investigations by both experiment and theoretical simulation, yet quantitative comparisons of the simulated data to the experimental results are rare. In this work, we present a novel way of comparing the temporal development of liquid-ordered domains obtained from numerically solving the Cahn-Hilliard equation and by inducing a phase transition in giant unilamellar vesicles (GUVs). Quantitative comparison is done by calculating the structure factor of the domain pattern. It turns out that the decomposition takes place in three distinct regimes in both experiment and simulation. These regimes are characterized by different rates of growth of the mean domain diameter, and there is quantitative agreement between experiment and simulation as to the duration of each regime and the absolute rate of growth in each regime.
NASA Astrophysics Data System (ADS)
Kemper, Björn; Bauwens, Andreas; Vollmer, Angelika; Ketelhut, Steffi; Langehanenberg, Patrik; Müthing, Johannes; Karch, Helge; von Bally, Gert
2010-05-01
Digital holographic microscopy (DHM) enables quantitative multifocus phase contrast imaging for nondestructive technical inspection and live cell analysis. Time-lapse investigations on human brain microvascular endothelial cells demonstrate the use of DHM for label-free dynamic quantitative monitoring of cell division of mother cells into daughter cells. Cytokinetic DHM analysis provides future applications in toxicology and cancer research.
ERIC Educational Resources Information Center
Ward, Peter J.; Walker, James J.
2008-01-01
The purpose of this investigation was to quantitatively and qualitatively identify the study methods and learning strategies that veterinary students used to study anatomy during their first year of professional school and to correlate these with their academic achievement and long-term recall of information. It was surmised that active study…
ERIC Educational Resources Information Center
Loomes, Susan; Croft, Amy
2013-01-01
This quantitative study provides a snapshot of the eating behaviour of more than 300 international students studying across four campuses of an Australian university. It explores what the students are eating and drinking, their knowledge of nutrition, the extent to which they prepare their own food or rely on fast food and if their behaviour is…
Exhaust-System Leak Test : Quantitative Procedure
DOT National Transportation Integrated Search
1974-01-01
A quantitative, periodic motor vehicle safety-inspection test for determining the leakage rate of engine exhaust from an automotive exhaust system was investigated. Two technical approaches were evaluated, and the better one was selected for developm...
Brunnenberg, M; Lindenblatt, H; Gouzoulis-Mayfrank, E; Kovar, K A
1998-11-20
A HPLC method has been developed for the analogue of Ecstasy MDE and its major metabolites N-ethyl-4-hydroxy-3-methoxyamphetamine (HME) and 3,4-methylenedioxyamphetamine (MDA) in human plasma. In the course of our investigations we found that the methylenedioxyamphetamines and HME exhibit fluorescence at 322 nm. Therefore the detection could be carried out with a fluorescence (FL) detector. Solid-phase extraction was used for sample preparation and yielded high recovery rates greater than 95%. The limit of quantitation for MDE and its metabolites in the extracts was between 1.5 and 8.9 ng/ml and the method standard deviations were less than 5%. This sensitive, rapid and reliable analytical method has been used successfully in the quantitation of the substances in plasma samples obtained from 14 volunteers in two clinical studies after p.o. administration of 100 to 140 mg MDE*HCI. The maximum plasma concentrations were 235-465 ng/ml (MDE), 67-673 ng/ml (HME) and 7-33 ng/ml (MDA), respectively. Pharmacokinetic parameters have been investigated using the plasma concentration curves.
Allesø, Morten; Holm, Per; Carstensen, Jens Michael; Holm, René
2016-05-25
Surface topography, in the context of surface smoothness/roughness, was investigated by the use of an image analysis technique, MultiRay™, related to photometric stereo, on different tablet batches manufactured either by direct compression or roller compaction. In the present study, oblique illumination of the tablet (darkfield) was considered and the area of cracks and pores in the surface was used as a measure of tablet surface topography; the higher a value, the rougher the surface. The investigations demonstrated a high precision of the proposed technique, which was able to rapidly (within milliseconds) and quantitatively measure the obtained surface topography of the produced tablets. Compaction history, in the form of applied roll force and tablet punch pressure, was also reflected in the measured smoothness of the tablet surfaces. Generally it was found that a higher degree of plastic deformation of the microcrystalline cellulose resulted in a smoother tablet surface. This altogether demonstrated that the technique provides the pharmaceutical developer with a reliable, quantitative response parameter for visual appearance of solid dosage forms, which may be used for process and ultimately product optimization. Copyright © 2015 Elsevier B.V. All rights reserved.
Rodríguez Chialanza, Mauricio; Sierra, Ignacio; Pérez Parada, Andrés; Fornaro, Laura
2018-06-01
There are several techniques used to analyze microplastics. These are often based on a combination of visual and spectroscopic techniques. Here we introduce an alternative workflow for identification and mass quantitation through a combination of optical microscopy with image analysis (IA) and differential scanning calorimetry (DSC). We studied four synthetic polymers with environmental concern: low and high density polyethylene (LDPE and HDPE, respectively), polypropylene (PP), and polyethylene terephthalate (PET). Selected experiments were conducted to investigate (i) particle characterization and counting procedures based on image analysis with open-source software, (ii) chemical identification of microplastics based on DSC signal processing, (iii) dependence of particle size on DSC signal, and (iv) quantitation of microplastics mass based on DSC signal. We describe the potential and limitations of these techniques to increase reliability for microplastic analysis. Particle size demonstrated to have particular incidence in the qualitative and quantitative performance of DSC signals. Both, identification (based on characteristic onset temperature) and mass quantitation (based on heat flow) showed to be affected by particle size. As a result, a proper sample treatment which includes sieving of suspended particles is particularly required for this analytical approach.
Wang, Shunhai; Bobst, Cedric E.; Kaltashov, Igor A.
2018-01-01
Transferrin (Tf) is an 80 kDa iron-binding protein which is viewed as a promising drug carrier to target the central nervous system due to its ability to penetrate the blood-brain barrier (BBB). Among the many challenges during the development of Tf-based therapeutics, sensitive and accurate quantitation of the administered Tf in cerebrospinal fluid (CSF) remains particularly difficult due to the presence of abundant endogenous Tf. Herein, we describe the development of a new LC-MS based method for sensitive and accurate quantitation of exogenous recombinant human Tf in rat CSF. By taking advantage of a His-tag present in recombinant Tf and applying Ni affinity purification, the exogenous hTf can be greatly enriched from rat CSF, despite the presence of the abundant endogenous protein. Additionally, we applied a newly developed O18-labeling technique that can generate internal standards at the protein level, which greatly improved the accuracy and robustness of quantitation. The developed method was investigated for linearity, accuracy, precision and lower limit of quantitation, all of which met the commonly accepted criteria for bioanalytical method validation. PMID:26307718
An Investigation of Backflow Phenomenon in Centrifugal Compressors
NASA Technical Reports Server (NTRS)
Benser, William A; Moses, Jason J
1945-01-01
Report presents the results of an investigation conducted to determine the nature and the extent of the reversal of flow, which occurs at the inlet of centrifugal compressors over a considerable portion of the operating range. Qualitative studies of this flow reversal were made by lampblack patterns taken on a mixed-flow-type impeller and by tuft studies made on a conventional centrifugal compressor. Quantitative studies were made on a compressor specially designed to enable survey of angularity of flow, static and total pressures, and temperatures to be taken very close to the impeller front housing.
Kaiser, Jozef; Holá, Markéta; Galiová, Michaela; Novotný, Karel; Kanický, Viktor; Martinec, Petr; Sčučka, Jiří; Brun, Francesco; Sodini, Nicola; Tromba, Giuliana; Mancini, Lucia; Kořistková, Tamara
2011-08-01
The outcomes from the feasibility study on utilization of synchrotron radiation X-ray microtomography (SR-μCT) to investigate the texture and the quantitative mineralogical composition of selected calcium oxalate-based urinary calculi fragments are presented. The comparison of the results obtained by SR-μCT analysis with those derived from current standard analytical approaches is provided. SR-μCT is proved as a potential effective technique for determination of texture, 3D microstructure, and composition of kidney stones.
Kim, Yoon Hyuk; Yao, Zhidong; Kim, Kyungsoo; Park, Won Man
2014-06-01
It may be assumed that the stability is affected when some ligaments are injured or loosened, and this joint instability causes sacroiliac joint pain. Several physical examinations have been used to diagnose sacroiliac pain and to isolate the source of the pain. However, more quantitative and objective information may be necessary to identify unstable or injured ligaments during these tests due to the lack of understanding of the quantitative relationship between the physical tests and the biomechanical parameters that may be related to pains in the sacroiliac joint and the surrounding ligaments. In this study, a three-dimensional finite element model of the sacroiliac joint was developed and the biomechanical conditions for six typical physical tests such as the compression test, distraction test, sacral apex pressure test, thigh thrust test, Patrick's test, and Gaenslen's test were modelled. The sacroiliac joint contact pressure and ligament strain were investigated for each test. The values of contact pressure and the combination of most highly strained ligaments differed markedly among the tests. Therefore, these findings in combination with the physical tests would be helpful to identify the pain source and to understand the pain mechanism. Moreover, the technology provided in this study might be a useful tool to evaluate the physical tests, to improve the present test protocols, or to develop a new physical test protocol. Copyright © 2013 Elsevier Ltd. All rights reserved.
Rivoira, Luca; Appendini, Marta; Fiorilli, Sonia; Onida, Barbara; Del Bubba, Massimo; Bruzzoniti, Maria Concetta
2016-11-01
Glyphosate is a worldwide-used herbicide occurring in many monitoring campaigns. Efficient technologies are currently unavailable for glyphosate removal from waters. In this work, a SBA-15 mesoporous silica-based material (Fe-NH 2 -SBA-15) was synthesized and studied for the adsorption of glyphosate from waters. In order to promote specific interactions between the sorbent and glyphosate via phosphoric group, iron oxide nanoparticles were encapsulated and a surface functionalization with (3-aminopropyl)triethoxysilane was accomplished. The adsorption of glyphosate on Fe-NH 2 -SBA-15 was investigated as a function of (i) pH, (ii) ionic strength (I), and (iii) adsorbate to adsorbent ratio (C), using a two-level, three-factor experimental design. The experimental design allowed for understanding the effect of the abovementioned variables and for proposing experimental conditions for quantitative removal (pH = 2.1, I = 1⋅10 -2 M and C = 0.35) under both batch and dynamic conditions. Interaction mechanism between glyphosate and Fe-NH 2 -SBA-15 sorbent was elucidated by studying the adsorption behavior of sorbents derived from the intermediate stages of synthesis and by desorption tests. Fe-NH 2 -SBA-15 sorbent can be quantitatively regenerated by 12.5 mM NaOH, and can be reused at least for five adsorption/desorption cycles. Quantitative removal of glyphosate from inlet and effluent wastewaters from a wastewater treatment plant is shown.
Testicular Dysgenesis Syndrome and the Estrogen Hypothesis: A Quantitative Meta-Analysis
Martin, Olwenn V.; Shialis, Tassos; Lester, John N.; Scrimshaw, Mark D.; Boobis, Alan R.; Voulvoulis, Nikolaos
2008-01-01
Background Male reproductive tract abnormalities such as hypospadias and cryptorchidism, and testicular cancer have been proposed to comprise a common syndrome together with impaired spermatogenesis with a common etiology resulting from the disruption of gonadal development during fetal life, the testicular dysgenesis syndrome (TDS). The hypothesis that in utero exposure to estrogenic agents could induce these disorders was first proposed in 1993. The only quantitative summary estimate of the association between prenatal exposure to estrogenic agents and testicular cancer was published over 10 years ago, and other systematic reviews of the association between estrogenic compounds, other than the potent pharmaceutical estrogen diethylstilbestrol (DES), and TDS end points have remained inconclusive. Objectives We conducted a quantitative meta-analysis of the association between the end points related to TDS and prenatal exposure to estrogenic agents. Inclusion in this analysis was based on mechanistic criteria, and the plausibility of an estrogen receptor (ER)-α–mediated mode of action was specifically explored. Results We included in this meta-analysis eight studies investigating the etiology of hypospadias and/or cryptorchidism that had not been identified in previous systematic reviews. Four additional studies of pharmaceutical estrogens yielded a statistically significant updated summary estimate for testicular cancer. Conclusions The doubling of the risk ratios for all three end points investigated after DES exposure is consistent with a shared etiology and the TDS hypothesis but does not constitute evidence of an estrogenic mode of action. Results of the subset analyses point to the existence of unidentified sources of heterogeneity between studies or within the study population. PMID:18288311
Testicular dysgenesis syndrome and the estrogen hypothesis: a quantitative meta-analysis.
Martin, Olwenn V; Shialis, Tassos; Lester, John N; Scrimshaw, Mark D; Boobis, Alan R; Voulvoulis, Nikolaos
2008-02-01
Male reproductive tract abnormalities such as hypospadias and cryptorchidism, and testicular cancer have been proposed to comprise a common syndrome together with impaired spermatogenesis with a common etiology resulting from the disruption of gonadal development during fetal life, the testicular dysgenesis syndrome (TDS). The hypothesis that in utero exposure to estrogenic agents could induce these disorders was first proposed in 1993. The only quantitative summary estimate of the association between prenatal exposure to estrogenic agents and testicular cancer was published over 10 years ago, and other systematic reviews of the association between estrogenic compounds, other than the potent pharmaceutical estrogen diethylstilbestrol (DES), and TDS end points have remained inconclusive. We conducted a quantitative meta-analysis of the association between the end points related to TDS and prenatal exposure to estrogenic agents. Inclusion in this analysis was based on mechanistic criteria, and the plausibility of an estrogen receptor (ER)-alpha-mediated mode of action was specifically explored. We included in this meta-analysis eight studies investigating the etiology of hypospadias and/or cryptorchidism that had not been identified in previous systematic reviews. Four additional studies of pharmaceutical estrogens yielded a statistically significant updated summary estimate for testicular cancer. The doubling of the risk ratios for all three end points investigated after DES exposure is consistent with a shared etiology and the TDS hypothesis but does not constitute evidence of an estrogenic mode of action. Results of the subset analyses point to the existence of unidentified sources of heterogeneity between studies or within the study population.
NASA Astrophysics Data System (ADS)
Berger, D.; Nissen, J.
2018-01-01
The studies in this paper are part of systematic investigations of the lateral analytical resolution of the field emission electron microprobe JEOL JXA-8530F. Hereby, the quantitative lateral resolution, which is achieved in practise, is in the focus of interest. The approach is to determine the minimum thickness of a metallic layer for which an accurate quantitative element analysis in cross-section is still possible. Previous measurements were accomplished at sputtered gold (Z = 79) layers, where a lateral resolution in the range of 140 to 170 nm was achieved at suitable parameters of the microprobe. To study the Z-dependence of the lateral resolution, now aluminium (Z = 13) resp. silver (Z = 47) layers with different thicknesses were generated by evaporation and prepared in cross-section subsequently by use of a focussed Ga-ion beam (FIB). Each layer was analysed quantitatively with different electron energies. The thinnest layer which can be resolved specifies the best lateral resolution. These measured values were compared on the one hand with Monte Carlo simulations and on the other hand with predictions from formulas from the literature. The measurements fit well to the simulated and calculated values, except the ones at the lowest primary electron energies with an overvoltage below ˜ 2. The reason for this discrepancy is not clear yet and has to be clarified by further investigations. The results apply for any microanalyser - even with energy-dispersive X-ray spectrometry (EDS) detection - if the probe diameters, which might deviate from those of the JEOL JXA-8530F, at suitable analysing parameters are considered.
Phommasone, Koukeo; Althaus, Thomas; Souvanthong, Phonesavanh; Phakhounthong, Khansoudaphone; Soyvienvong, Laxoy; Malapheth, Phatthaphone; Mayxay, Mayfong; Pavlicek, Rebecca L; Paris, Daniel H; Dance, David; Newton, Paul; Lubell, Yoel
2016-02-04
C-Reactive Protein (CRP) has been shown to be an accurate biomarker for discriminating bacterial from viral infections in febrile patients in Southeast Asia. Here we investigate the accuracy of existing rapid qualitative and semi-quantitative tests as compared with a quantitative reference test to assess their potential for use in remote tropical settings. Blood samples were obtained from consecutive patients recruited to a prospective fever study at three sites in rural Laos. At each site, one of three rapid qualitative or semi-quantitative tests was performed, as well as a corresponding quantitative NycoCard Reader II as a reference test. We estimate the sensitivity and specificity of the three tests against a threshold of 10 mg/L and kappa values for the agreement of the two semi-quantitative tests with the results of the reference test. All three tests showed high sensitivity, specificity and kappa values as compared with the NycoCard Reader II. With a threshold of 10 mg/L the sensitivity of the tests ranged from 87-98 % and the specificity from 91-98 %. The weighted kappa values for the semi-quantitative tests were 0.7 and 0.8. The use of CRP rapid tests could offer an inexpensive and effective approach to improve the targeting of antibiotics in remote settings where health facilities are basic and laboratories are absent. This study demonstrates that accurate CRP rapid tests are commercially available; evaluations of their clinical impact and cost-effectiveness at point of care is warranted.
Hematocrit Measurement with R2* and Quantitative Susceptibility Mapping in Postmortem Brain.
Walsh, A J; Sun, H; Emery, D J; Wilman, A H
2018-05-24
Noninvasive venous oxygenation quantification with MR imaging will improve the neurophysiologic investigation and the understanding of the pathophysiology in neurologic diseases. Available MR imaging methods are limited by sensitivity to flow and often require assumptions of the hematocrit level. In situ postmortem imaging enables evaluation of methods in a fully deoxygenated environment without flow artifacts, allowing direct calculation of hematocrit. This study compares 2 venous oxygenation quantification methods in in situ postmortem subjects. Transverse relaxation (R2*) mapping and quantitative susceptibility mapping were performed on a whole-body 4.7T MR imaging system. Intravenous measurements in major draining intracranial veins were compared between the 2 methods in 3 postmortem subjects. The quantitative susceptibility mapping technique was also applied in 10 healthy control subjects and compared with reference venous oxygenation values. In 2 early postmortem subjects, R2* mapping and quantitative susceptibility mapping measurements within intracranial veins had a significant and strong correlation ( R 2 = 0.805, P = .004 and R 2 = 0.836, P = .02). Higher R2* and susceptibility values were consistently demonstrated within gravitationally dependent venous segments during the early postmortem period. Hematocrit ranged from 0.102 to 0.580 in postmortem subjects, with R2* and susceptibility as large as 291 seconds -1 and 1.75 ppm, respectively. Measurements of R2* and quantitative susceptibility mapping within large intracranial draining veins have a high correlation in early postmortem subjects. This study supports the use of quantitative susceptibility mapping for evaluation of in vivo venous oxygenation and postmortem hematocrit concentrations. © 2018 by American Journal of Neuroradiology.
Cehreli, S Burcak; Polat-Ozsoy, Omur; Sar, Cagla; Cubukcu, H Evren; Cehreli, Zafer C
2012-04-01
The amount of the residual adhesive after bracket debonding is frequently assessed in a qualitative manner, utilizing the adhesive remnant index (ARI). This study aimed to investigate whether quantitative assessment of the adhesive remnant yields more precise results compared to qualitative methods utilizing the 4- and 5-point ARI scales. Twenty debonded brackets were selected. Evaluation and scoring of the adhesive remnant on bracket bases were made consecutively using: 1. qualitative assessment (visual scoring) and 2. quantitative measurement (image analysis) on digital photographs. Image analysis was made on scanning electron micrographs (SEM) and high-precision elemental maps of the adhesive remnant as determined by energy dispersed X-ray spectrometry. Evaluations were made in accordance with the original 4-point and the modified 5-point ARI scales. Intra-class correlation coefficients (ICCs) were calculated, and the data were evaluated using Friedman test followed by Wilcoxon signed ranks test with Bonferroni correction. ICC statistics indicated high levels of agreement for qualitative visual scoring among examiners. The 4-point ARI scale was compliant with the SEM assessments but indicated significantly less adhesive remnant compared to the results of quantitative elemental mapping. When the 5-point scale was used, both quantitative techniques yielded similar results with those obtained qualitatively. These results indicate that qualitative visual scoring using the ARI is capable of generating similar results with those assessed by quantitative image analysis techniques. In particular, visual scoring with the 5-point ARI scale can yield similar results with both the SEM analysis and elemental mapping.
Measuring social interaction in music ensembles
D'Ausilio, Alessandro; Badino, Leonardo; Camurri, Antonio; Fadiga, Luciano
2016-01-01
Music ensembles are an ideal test-bed for quantitative analysis of social interaction. Music is an inherently social activity, and music ensembles offer a broad variety of scenarios which are particularly suitable for investigation. Small ensembles, such as string quartets, are deemed a significant example of self-managed teams, where all musicians contribute equally to a task. In bigger ensembles, such as orchestras, the relationship between a leader (the conductor) and a group of followers (the musicians) clearly emerges. This paper presents an overview of recent research on social interaction in music ensembles with a particular focus on (i) studies from cognitive neuroscience; and (ii) studies adopting a computational approach for carrying out automatic quantitative analysis of ensemble music performances. PMID:27069054
Measuring social interaction in music ensembles.
Volpe, Gualtiero; D'Ausilio, Alessandro; Badino, Leonardo; Camurri, Antonio; Fadiga, Luciano
2016-05-05
Music ensembles are an ideal test-bed for quantitative analysis of social interaction. Music is an inherently social activity, and music ensembles offer a broad variety of scenarios which are particularly suitable for investigation. Small ensembles, such as string quartets, are deemed a significant example of self-managed teams, where all musicians contribute equally to a task. In bigger ensembles, such as orchestras, the relationship between a leader (the conductor) and a group of followers (the musicians) clearly emerges. This paper presents an overview of recent research on social interaction in music ensembles with a particular focus on (i) studies from cognitive neuroscience; and (ii) studies adopting a computational approach for carrying out automatic quantitative analysis of ensemble music performances. © 2016 The Author(s).
Metrology Standards for Quantitative Imaging Biomarkers
Obuchowski, Nancy A.; Kessler, Larry G.; Raunig, David L.; Gatsonis, Constantine; Huang, Erich P.; Kondratovich, Marina; McShane, Lisa M.; Reeves, Anthony P.; Barboriak, Daniel P.; Guimaraes, Alexander R.; Wahl, Richard L.
2015-01-01
Although investigators in the imaging community have been active in developing and evaluating quantitative imaging biomarkers (QIBs), the development and implementation of QIBs have been hampered by the inconsistent or incorrect use of terminology or methods for technical performance and statistical concepts. Technical performance is an assessment of how a test performs in reference objects or subjects under controlled conditions. In this article, some of the relevant statistical concepts are reviewed, methods that can be used for evaluating and comparing QIBs are described, and some of the technical performance issues related to imaging biomarkers are discussed. More consistent and correct use of terminology and study design principles will improve clinical research, advance regulatory science, and foster better care for patients who undergo imaging studies. © RSNA, 2015 PMID:26267831
Quantitative impact of direct, personal feedback on hand hygiene technique.
Lehotsky, Á; Szilágyi, L; Ferenci, T; Kovács, L; Pethes, R; Wéber, G; Haidegger, T
2015-09-01
This study investigated the effectiveness of targeting hand hygiene technique using a new training device that provides objective, personal and quantitative feedback. One hundred and thirty-six healthcare workers in three Hungarian hospitals participated in a repetitive hand hygiene technique assessment study. Ultraviolet (UV)-labelled hand rub was used at each event, and digital images of the hands were subsequently taken under UV light. Immediate objective visual feedback was given to participants, showing missed areas on their hands. The rate of inadequate hand rubbing reduced from 50% to 15% (P < 0.001). However, maintenance of this reduced rate is likely to require continuous use of the electronic equipment. Copyright © 2015 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.
Impact of Summer Recess on Mathematics Learning Retention
ERIC Educational Resources Information Center
Hornack, David
2016-01-01
School administrators across the nation are actively searching for solutions to increase student achievement due in part to the significant amount of knowledge that is lost annually each summer. Mathematical computation skills are especially at-risk. This quantitative research study was designed to investigate the impact of summer recess also…
Reasons for Vocabulary Attrition: Revisiting the State of the Art
ERIC Educational Resources Information Center
Alharthi, Thamer
2015-01-01
This paper reports on a one year, mixed-methods longitudinal case study investigating the neglected area of the perceived reasons why participants forget vocabulary knowledge. The participants were 43 fourth year male Saudi EFL majors at King Abdulaziz University KAU, Saudi Arabia. Quantitative and qualitative data including self-reported…
Equity in Assistance? Usability of a U.S. Government Food Assistance Application
ERIC Educational Resources Information Center
Saal, Leah Katherine
2016-01-01
This article focuses on the quantitative phase of a multiphase mixed methods study investigating adults' and families' access to government food assistance. The research evaluates participants' comprehension of, and ability to, adequately complete authentic complex texts--national food assistance application documents. Summative usability testing…
Illicit Use of Prescription ADHD Medications on a College Campus: A Multimethodological Approach
ERIC Educational Resources Information Center
DeSantis, Alan D.; Webb, Elizabeth M.; Noar, Seth M.
2008-01-01
Objective: The authors used quantitative and qualitative methodologies to investigate college students' perceptions and use of illegal Attention Deficit Hyperactivity Disorder (ADHD) stimulants during spring and summer 2006. Participants: From fall 2005 through fall 2006, the authors studied 1,811 undergraduates at a large, public, southeastern…
An Investigation of Chief Administrator Turnover in International Schools
ERIC Educational Resources Information Center
Benson, John
2011-01-01
This article explores chief administrator turnover in international schools. Quantitative and qualitative data from the 83 chief administrators who participated in the study suggests that the average tenure of an international school chief administrator is 3.7 years and that the main reason chief administrators leave international schools is…
Learning Science via Animated Movies: Its Effect on Students' Thinking and Motivation
ERIC Educational Resources Information Center
Barak, Miri; Ashkar, Tamar; Dori, Yehudit J.
2011-01-01
Some researchers claim that animations may hinder students' meaningful learning or evoke misunderstandings. In order to examine these assertions, our study investigated the effect of animated movies on students' learning outcomes and motivation to learn. Applying the quantitative methodology, two pre- and post-questionnaires were administered:…
Effectiveness of Career Counseling: A One-Year Follow-Up
ERIC Educational Resources Information Center
Perdrix, Sophie; Stauffer, Sarah; Masdonati, Jonas; Massoudi, Koorosh; Rossier, Jerome
2012-01-01
The short-term effectiveness of career counseling is well supported in the literature. However, the long-term impact is often overlooked. This study quantitatively investigated the long-term stability of the positive effects gained through the career counseling process and qualitatively observed participants' levels of career project…
Faculty Professional Development and Student Satisfaction in Online Higher Education
ERIC Educational Resources Information Center
Kane, Robert Todd; Shaw, Melanie; Pang, Sangho; Salley, Witt; Snider, J. Blake
2016-01-01
With the ever-increasing availability of online education opportunities, understanding the factors that influence online student satisfaction and success is vital to enable administrators to engage and retain this important stakeholder group. The purpose of this ex-post-facto, nonexperimental quantitative study was to investigate the impact of…
Effects of Peer Tutoring on Reading Self-Concept
ERIC Educational Resources Information Center
Flores, Marta; Duran, David
2013-01-01
This study investigates the development of the Reading Self-Concept and of the mechanisms underlying it, within a framework of a reading programme based on peer tutoring. The multiple methodological design adopted allowed for a quantitative approach which showed statistically significant changes in the Reading Self-Concept of those students who…
Comparing Higher Education Practices and Cultural Competences in Kenya and the United States
ERIC Educational Resources Information Center
Musamali, Kennedy; Martin, Barbara N.
2016-01-01
Examined within this paper are effective leadership practices across two cultures. Specifically, this study examined the relationship between cultural competency and effective leadership practices in higher education institutions. A quantitative design was used to investigate and compare effective practices of educational leaders in two distinct…
Task-Induced Variability in FL Composition: Language-Specific Perspectives.
ERIC Educational Resources Information Center
Koda, Keiko
1993-01-01
Investigated ways in which different writing tasks influence quality and quantity of foreign language composition, as well as writing strategies used by American college students when composing in Japanese as a foreign language. Study proposed to compare qualitative and quantitative differences between descriptive and narrative writing tasks; to…