Sample records for quick response codes

  1. Using Quick Response Codes in the Classroom: Quality Outcomes.

    PubMed

    Zurmehly, Joyce; Adams, Kellie

    2017-10-01

    With smart device technology emerging, educators are challenged with redesigning teaching strategies using technology to allow students to participate dynamically and provide immediate answers. To facilitate integration of technology and to actively engage students, quick response codes were included in a medical surgical lecture. Quick response codes are two-dimensional square patterns that enable the coding or storage of more than 7000 characters that can be accessed via a quick response code scanning application. The aim of this quasi-experimental study was to explore quick response code use in a lecture and measure students' satisfaction (met expectations, increased interest, helped understand, and provided practice and prompt feedback) and engagement (liked most, liked least, wanted changed, and kept involved), assessed using an investigator-developed instrument. Although there was no statistically significant correlation of quick response use to examination scores, satisfaction scores were high, and there was a small yet positive association between how students perceived their learning with quick response codes and overall examination scores. Furthermore, on open-ended survey questions, students responded that they were satisfied with the use of quick response codes, appreciated the immediate feedback, and planned to use them in the clinical setting. Quick response codes offer a way to integrate technology into the classroom to provide students with instant positive feedback.

  2. The Mystery Behind the Code: Differentiated Instruction with Quick Response Codes in Secondary Physical Education

    ERIC Educational Resources Information Center

    Adkins, Megan; Wajciechowski, Misti R.; Scantling, Ed

    2013-01-01

    Quick response codes, better known as QR codes, are small barcodes scanned to receive information about a specific topic. This article explains QR code technology and the utility of QR codes in the delivery of physical education instruction. Consideration is given to how QR codes can be used to accommodate learners of varying ability levels as…

  3. Quick Response (QR) Codes for Audio Support in Foreign Language Learning

    ERIC Educational Resources Information Center

    Vigil, Kathleen Murray

    2017-01-01

    This study explored the potential benefits and barriers of using quick response (QR) codes as a means by which to provide audio materials to middle-school students learning Spanish as a foreign language. Eleven teachers of Spanish to middle-school students created transmedia materials containing QR codes linking to audio resources. Students…

  4. Pre-Service Teachers' Perception of Quick Response (QR) Code Integration in Classroom Activities

    ERIC Educational Resources Information Center

    Ali, Nagla; Santos, Ieda M.; Areepattamannil, Shaljan

    2017-01-01

    Quick Response (QR) codes have been discussed in the literature as adding value to teaching and learning. Despite their potential in education, more research is needed to inform practice and advance knowledge in this field. This paper investigated the integration of the QR code in classroom activities and the perceptions of the integration by…

  5. Investigating the Use of Quick Response Codes in the Gross Anatomy Laboratory

    ERIC Educational Resources Information Center

    Traser, Courtney J.; Hoffman, Leslie A.; Seifert, Mark F.; Wilson, Adam B.

    2015-01-01

    The use of quick response (QR) codes within undergraduate university courses is on the rise, yet literature concerning their use in medical education is scant. This study examined student perceptions on the usefulness of QR codes as learning aids in a medical gross anatomy course, statistically analyzed whether this learning aid impacted student…

  6. Microparticles: Facile and High-Throughput Synthesis of Functional Microparticles with Quick Response Codes (Small 24/2016).

    PubMed

    Ramirez, Lisa Marie S; He, Muhan; Mailloux, Shay; George, Justin; Wang, Jun

    2016-06-01

    Microparticles carrying quick response (QR) barcodes are fabricated by J. Wang and co-workers on page 3259, using a massive coding of dissociated elements (MiCODE) technology. Each microparticle can bear a special custom-designed QR code that enables encryption or tagging with unlimited multiplexity, and the QR code can be easily read by cellphone applications. The utility of MiCODE particles in multiplexed DNA detection and microtagging for anti-counterfeiting is explored. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  7. Optical noise-free image encryption based on quick response code and high dimension chaotic system in gyrator transform domain

    NASA Astrophysics Data System (ADS)

    Sui, Liansheng; Xu, Minjie; Tian, Ailing

    2017-04-01

    A novel optical image encryption scheme is proposed based on quick response code and high dimension chaotic system, where only the intensity distribution of encoded information is recorded as ciphertext. Initially, the quick response code is engendered from the plain image and placed in the input plane of the double random phase encoding architecture. Then, the code is encrypted to the ciphertext with noise-like distribution by using two cascaded gyrator transforms. In the process of encryption, the parameters such as rotation angles and random phase masks are generated as interim variables and functions based on Chen system. A new phase retrieval algorithm is designed to reconstruct the initial quick response code in the process of decryption, in which a priori information such as three position detection patterns is used as the support constraint. The original image can be obtained without any energy loss by scanning the decrypted code with mobile devices. The ciphertext image is the real-valued function which is more convenient for storing and transmitting. Meanwhile, the security of the proposed scheme is enhanced greatly due to high sensitivity of initial values of Chen system. Extensive cryptanalysis and simulation have performed to demonstrate the feasibility and effectiveness of the proposed scheme.

  8. A Learning Environment for English Vocabulary Using Quick Response Codes

    ERIC Educational Resources Information Center

    Arikan, Yuksel Deniz; Ozen, Sevil Orhan

    2015-01-01

    This study focuses on the process of developing a learning environment that uses tablets and Quick Response (QR) codes to enhance participants' English language vocabulary knowledge. The author employed the concurrent triangulation strategy, a mixed research design. The study was conducted at a private school in Izmir, Turkey during the 2012-2013…

  9. What Are Those Checkerboard Things? How Quick Response Codes Can Enrich Student Projects

    ERIC Educational Resources Information Center

    Tucker, Al

    2011-01-01

    Students enrolled in the author's commercial arts program design and publish the school's yearbook. For the 2010-2011 school year, the students applied Quick Response (QR) code technology to include links to events that occurred after the yearbook's print deadline, including graduation. The technology has many applications in the school setting,…

  10. Rethinking mobile delivery: using Quick Response codes to access information at the point of need.

    PubMed

    Lombardo, Nancy T; Morrow, Anne; Le Ber, Jeanne

    2012-01-01

    This article covers the use of Quick Response (QR) codes to provide instant mobile access to information, digital collections, educational offerings, library website, subject guides, text messages, videos, and library personnel. The array of uses and the value of using QR codes to push customized information to patrons are explained. A case is developed for using QR codes for mobile delivery of customized information to patrons. Applications in use at the Libraries of the University of Utah will be reviewed to provide readers with ideas for use in their library. Copyright © Taylor & Francis Group, LLC

  11. An introduction to QR Codes: linking libraries and mobile patrons.

    PubMed

    Hoy, Matthew B

    2011-01-01

    QR codes, or "Quick Response" codes, are two-dimensional barcodes that can be scanned by mobile smartphone cameras. These codes can be used to provide fast access to URLs, telephone numbers, and short passages of text. With the rapid adoption of smartphones, librarians are able to use QR codes to promote services and help library users find materials quickly and independently. This article will explain what QR codes are, discuss how they can be used in the library, and describe issues surrounding their use. A list of resources for generating and scanning QR codes is also provided.

  12. Using QR codes to enable quick access to information in acute cancer care.

    PubMed

    Upton, Joanne; Olsson-Brown, Anna; Marshall, Ernie; Sacco, Joseph

    2017-05-25

    Quick access to toxicity management information ensures timely access to steroids/immunosuppressive treatment for cancer patients experiencing immune-related adverse events, thus reducing length of hospital stays or avoiding hospital admission entirely. This article discusses a project to add a QR (quick response) code to a patient-held immunotherapy alert card. As QR code generation is free and the immunotherapy clinical management algorithms were already publicly available through the trust's clinical network website, the costs of integrating a QR code into the alert card, after printing, were low, while the potential benefits are numerous. Patient-held alert cards are widely used for patients receiving anti-cancer treatment, and this established standard of care has been modified to enable rapid access of information through the incorporation of a QR code.

  13. Status and future plans for open source QuickPIC

    NASA Astrophysics Data System (ADS)

    An, Weiming; Decyk, Viktor; Mori, Warren

    2017-10-01

    QuickPIC is a three dimensional (3D) quasi-static particle-in-cell (PIC) code developed based on the UPIC framework. It can be used for efficiently modeling plasma based accelerator (PBA) problems. With quasi-static approximation, QuickPIC can use different time scales for calculating the beam (or laser) evolution and the plasma response, and a 3D plasma wake field can be simulated using a two-dimensional (2D) PIC code where the time variable is ξ = ct - z and z is the beam propagation direction. QuickPIC can be thousand times faster than the normal PIC code when simulating the PBA. It uses an MPI/OpenMP hybrid parallel algorithm, which can be run on either a laptop or the largest supercomputer. The open source QuickPIC is an object-oriented program with high level classes written in Fortran 2003. It can be found at https://github.com/UCLA-Plasma-Simulation-Group/QuickPIC-OpenSource.git

  14. An evaluation of the effect of JPEG, JPEG2000, and H.264/AVC on CQR codes decoding process

    NASA Astrophysics Data System (ADS)

    Vizcarra Melgar, Max E.; Farias, Mylène C. Q.; Zaghetto, Alexandre

    2015-02-01

    This paper presents a binarymatrix code based on QR Code (Quick Response Code), denoted as CQR Code (Colored Quick Response Code), and evaluates the effect of JPEG, JPEG2000 and H.264/AVC compression on the decoding process. The proposed CQR Code has three additional colors (red, green and blue), what enables twice as much storage capacity when compared to the traditional black and white QR Code. Using the Reed-Solomon error-correcting code, the CQR Code model has a theoretical correction capability of 38.41%. The goal of this paper is to evaluate the effect that degradations inserted by common image compression algorithms have on the decoding process. Results show that a successful decoding process can be achieved for compression rates up to 0.3877 bits/pixel, 0.1093 bits/pixel and 0.3808 bits/pixel for JPEG, JPEG2000 and H.264/AVC formats, respectively. The algorithm that presents the best performance is the H.264/AVC, followed by the JPEG2000, and JPEG.

  15. Use of quick response coding to create interactive patient and provider resources.

    PubMed

    Bellot, Jennifer; Shaffer, Kathryn; Wang, Mary

    2015-04-01

    Since their creation more than 20 years ago, the proliferation of Quick Response (QR) codes has expanded tremendously. Little was found in the literature to support the innovative use of QR coding in the classroom or in health care provision. Thus, the authors created a doctoral-level practicum experience using QR coding to create interactive, individualized patient or provider resource guides. Short, descriptive surveys were used before and after implementation of the practicum experience to determine students' comfort level using QR technology, their knowledge base, ease of use, and overall satisfaction with the practicum. Students reported high levels of satisfaction with this exercise, and all agreed that use of QR coding could have important implications in the clinical environment. This practicum experience was a creative, practical, and valuable example of integrating emerging technology into individualized patient care. Copyright 2015, SLACK Incorporated.

  16. QR Codes 101

    ERIC Educational Resources Information Center

    Crompton, Helen; LaFrance, Jason; van 't Hooft, Mark

    2012-01-01

    A QR (quick-response) code is a two-dimensional scannable code, similar in function to a traditional bar code that one might find on a product at the supermarket. The main difference between the two is that, while a traditional bar code can hold a maximum of only 20 digits, a QR code can hold up to 7,089 characters, so it can contain much more…

  17. Optical information authentication using compressed double-random-phase-encoded images and quick-response codes.

    PubMed

    Wang, Xiaogang; Chen, Wen; Chen, Xudong

    2015-03-09

    In this paper, we develop a new optical information authentication system based on compressed double-random-phase-encoded images and quick-response (QR) codes, where the parameters of optical lightwave are used as keys for optical decryption and the QR code is a key for verification. An input image attached with QR code is first optically encoded in a simplified double random phase encoding (DRPE) scheme without using interferometric setup. From the single encoded intensity pattern recorded by a CCD camera, a compressed double-random-phase-encoded image, i.e., the sparse phase distribution used for optical decryption, is generated by using an iterative phase retrieval technique with QR code. We compare this technique to the other two methods proposed in literature, i.e., Fresnel domain information authentication based on the classical DRPE with holographic technique and information authentication based on DRPE and phase retrieval algorithm. Simulation results show that QR codes are effective on improving the security and data sparsity of optical information encryption and authentication system.

  18. Digital data for quick response (QR) codes of alkalophilic Bacillus pumilus to identify and to compare bacilli isolated from Lonar Crator Lake, India.

    PubMed

    Rekadwad, Bhagwan N; Khobragade, Chandrahasya N

    2016-06-01

    Microbiologists are routinely engaged isolation, identification and comparison of isolated bacteria for their novelty. 16S rRNA sequences of Bacillus pumilus were retrieved from NCBI repository and generated QR codes for sequences (FASTA format and full Gene Bank information). 16SrRNA were used to generate quick response (QR) codes of Bacillus pumilus isolated from Lonar Crator Lake (19° 58' N; 76° 31' E), India. Bacillus pumilus 16S rRNA gene sequences were used to generate CGR, FCGR and PCA. These can be used for visual comparison and evaluation respectively. The hyperlinked QR codes, CGR, FCGR and PCA of all the isolates are made available to the users on a portal https://sites.google.com/site/bhagwanrekadwad/. This generated digital data helps to evaluate and compare any Bacillus pumilus strain, minimizes laboratory efforts and avoid misinterpretation of the species.

  19. [The QR code in society, economy and medicine--fields of application, options and chances].

    PubMed

    Flaig, Benno; Parzeller, Markus

    2011-01-01

    2D codes like the QR Code ("Quick Response") are becoming more and more common in society and medicine. The application spectrum and benefits in medicine and other fields are described. 2D codes can be created free of charge on any computer with internet access without any previous knowledge. The codes can be easily used in publications, presentations, on business cards and posters. Editors choose between contact details, text or a hyperlink as information behind the code. At expert conferences, linkage by QR Code allows the audience to download presentations and posters quickly. The documents obtained can then be saved, printed, processed etc. Fast access to stored data in the internet makes it possible to integrate additional and explanatory multilingual videos into medical posters. In this context, a combination of different technologies (printed handout, QR Code and screen) may be reasonable.

  20. Facile and High-Throughput Synthesis of Functional Microparticles with Quick Response Codes.

    PubMed

    Ramirez, Lisa Marie S; He, Muhan; Mailloux, Shay; George, Justin; Wang, Jun

    2016-06-01

    Encoded microparticles are high demand in multiplexed assays and labeling. However, the current methods for the synthesis and coding of microparticles either lack robustness and reliability, or possess limited coding capacity. Here, a massive coding of dissociated elements (MiCODE) technology based on innovation of a chemically reactive off-stoichimetry thiol-allyl photocurable polymer and standard lithography to produce a large number of quick response (QR) code microparticles is introduced. The coding process is performed by photobleaching the QR code patterns on microparticles when fluorophores are incorporated into the prepolymer formulation. The fabricated encoded microparticles can be released from a substrate without changing their features. Excess thiol functionality on the microparticle surface allows for grafting of amine groups and further DNA probes. A multiplexed assay is demonstrated using the DNA-grafted QR code microparticles. The MiCODE technology is further characterized by showing the incorporation of BODIPY-maleimide (BDP-M) and Nile Red fluorophores for coding and the use of microcontact printing for immobilizing DNA probes on microparticle surfaces. This versatile technology leverages mature lithography facilities for fabrication and thus is amenable to scale-up in the future, with potential applications in bioassays and in labeling consumer products. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. Use Them ... or Lose Them? The Case for and against Using QR Codes

    ERIC Educational Resources Information Center

    Cunningham, Chuck; Dull, Cassie

    2011-01-01

    A quick-response (QR) code is a two-dimensional, black-and-white square barcode and links directly to a URL of one's choice. When the code is scanned with a smartphone, it will automatically redirect the user to the designated URL. QR codes are popping up everywhere--billboards, magazines, posters, shop windows, TVs, computer screens, and more.…

  2. Blending Classroom Teaching and Learning with QR Codes

    ERIC Educational Resources Information Center

    Rikala, Jenni; Kankaanranta, Marja

    2014-01-01

    The aim of this case study was to explore the feasibility of the Quick Response (QR) codes and mobile devices in the context of Finnish basic education. The interest was especially to explore how mobile devices and QR codes can enhance and blend teaching and learning. The data were collected with a teacher interview and pupil surveys. The learning…

  3. Digital data for quick response (QR) codes of alkalophilic Bacillus pumilus to identify and to compare bacilli isolated from Lonar Crator Lake, India

    PubMed Central

    Rekadwad, Bhagwan N.; Khobragade, Chandrahasya N.

    2016-01-01

    Microbiologists are routinely engaged isolation, identification and comparison of isolated bacteria for their novelty. 16S rRNA sequences of Bacillus pumilus were retrieved from NCBI repository and generated QR codes for sequences (FASTA format and full Gene Bank information). 16SrRNA were used to generate quick response (QR) codes of Bacillus pumilus isolated from Lonar Crator Lake (19° 58′ N; 76° 31′ E), India. Bacillus pumilus 16S rRNA gene sequences were used to generate CGR, FCGR and PCA. These can be used for visual comparison and evaluation respectively. The hyperlinked QR codes, CGR, FCGR and PCA of all the isolates are made available to the users on a portal https://sites.google.com/site/bhagwanrekadwad/. This generated digital data helps to evaluate and compare any Bacillus pumilus strain, minimizes laboratory efforts and avoid misinterpretation of the species. PMID:27141529

  4. Location Based Service in Indoor Environment Using Quick Response Code Technology

    NASA Astrophysics Data System (ADS)

    Hakimpour, F.; Zare Zardiny, A.

    2014-10-01

    Today by extensive use of intelligent mobile phones, increased size of screens and enriching the mobile phones by Global Positioning System (GPS) technology use of location based services have been considered by public users more than ever.. Based on the position of users, they can receive the desired information from different LBS providers. Any LBS system generally includes five main parts: mobile devices, communication network, positioning system, service provider and data provider. By now many advances have been gained in relation to any of these parts; however the users positioning especially in indoor environments is propounded as an essential and critical issue in LBS. It is well known that GPS performs too poorly inside buildings to provide usable indoor positioning. On the other hand, current indoor positioning technologies such as using RFID or WiFi network need different hardware and software infrastructures. In this paper, we propose a new method to overcome these challenges. This method is using the Quick Response (QR) Code Technology. QR Code is a 2D encrypted barcode with a matrix structure which consists of black modules arranged in a square grid. Scanning and data retrieving process from QR Code is possible by use of different camera-enabled mobile phones only by installing the barcode reader software. This paper reviews the capabilities of QR Code technology and then discusses the advantages of using QR Code in Indoor LBS (ILBS) system in comparison to other technologies. Finally, some prospects of using QR Code are illustrated through implementation of a scenario. The most important advantages of using this new technology in ILBS are easy implementation, spending less expenses, quick data retrieval, possibility of printing the QR Code on different products and no need for complicated hardware and software infrastructures.

  5. QR Codes

    ERIC Educational Resources Information Center

    Lai, Hsin-Chih; Chang, Chun-Yen; Li, Wen-Shiane; Fan, Yu-Lin; Wu, Ying-Tien

    2013-01-01

    This study presents an m-learning method that incorporates Integrated Quick Response (QR) codes. This learning method not only achieves the objectives of outdoor education, but it also increases applications of Cognitive Theory of Multimedia Learning (CTML) (Mayer, 2001) in m-learning for practical use in a diverse range of outdoor locations. When…

  6. QR codes: next level of social media.

    PubMed

    Gottesman, Wesley; Baum, Neil

    2013-01-01

    The OR code, which is short for quick response code, system was invented in Japan for the auto industry. Its purpose was to track vehicles during manufacture; it was designed to allow high-speed component scanning. Now the scanning can be easily accomplished via cell phone, making the technology useful and within reach of your patients. There are numerous applications for OR codes in the contemporary medical practice. This article describes QR codes and how they might be applied for marketing and practice management.

  7. What Are Those Checkerboard Things?: How QR Codes Can Enrich Student Projects

    ERIC Educational Resources Information Center

    Tucker, Al

    2011-01-01

    Students enrolled in commercial arts program design and publish their school's yearbook. For the 2010-2011 school year, the students applied Quick Response (QR) code technology to include links to events that occurred after the yearbook's print deadline, including graduation. The technology has many applications in the school setting, and the…

  8. Enhancing Nursing and Midwifery Student Learning Through the Use of QR Codes.

    PubMed

    Downer, Terri; Oprescu, Florin; Forbes, Helen; Phillips, Nikki; McTier, Lauren; Lord, Bill; Barr, Nigel; Bright, Peter; Simbag, Vilma

    A recent teaching and learning innovation using new technologies involves the use of quick response codes, which are read by smartphones and tablets. Integrating this technology as a teaching and learning strategy in nursing and midwifery education has been embraced by academics and students at a regional university.

  9. Anticounterfeiting Quick Response Code with Emission Color of Invisible Metal-Organic Frameworks as Encoding Information.

    PubMed

    Wang, Yong-Mei; Tian, Xue-Tao; Zhang, Hui; Yang, Zhong-Rui; Yin, Xue-Bo

    2018-06-21

    Counterfeiting is a global epidemic that is compelling the development of new anticounterfeiting strategy. Herein, we report a novel multiple anticounterfeiting encoding strategy of invisible fluorescent quick response (QR) codes with emission color as information storage unit. The strategy requires red, green, and blue (RGB) light-emitting materials for different emission colors as encrypting information, single excitation for all of the emission for practicability, and ultraviolet (UV) excitation for invisibility under daylight. Therefore, RGB light-emitting nanoscale metal-organic frameworks (NMOFs) are designed as inks to construct the colorful light-emitting boxes for information encrypting, while three black vertex boxes were used for positioning. Full-color emissions are obtained by mixing the trichromatic NMOFs inks through inkjet printer. The encrypting information capacity is easily adjusted by the number of light-emitting boxes with the infinite emission colors. The information is decoded with specific excitation light at 275 nm, making the QR codes invisible under daylight. The composition of inks, invisibility, inkjet printing, and the abundant encrypting information all contribute to multiple anticounterfeiting. The proposed QR codes pattern holds great potential for advanced anticounterfeiting.

  10. Self-Powered Forward Error-Correcting Biosensor Based on Integration of Paper-Based Microfluidics and Self-Assembled Quick Response Codes.

    PubMed

    Yuan, Mingquan; Liu, Keng-Ku; Singamaneni, Srikanth; Chakrabartty, Shantanu

    2016-10-01

    This paper extends our previous work on silver-enhancement based self-assembling structures for designing reliable, self-powered biosensors with forward error correcting (FEC) capability. At the core of the proposed approach is the integration of paper-based microfluidics with quick response (QR) codes that can be optically scanned using a smart-phone. The scanned information is first decoded to obtain the location of a web-server which further processes the self-assembled QR image to determine the concentration of target analytes. The integration substrate for the proposed FEC biosensor is polyethylene and the patterning of the QR code on the substrate has been achieved using a combination of low-cost ink-jet printing and a regular ballpoint dispensing pen. A paper-based microfluidics channel has been integrated underneath the substrate for acquiring, mixing and flowing the sample to areas on the substrate where different parts of the code can self-assemble in presence of immobilized gold nanorods. In this paper we demonstrate the proof-of-concept detection using prototypes of QR encoded FEC biosensors.

  11. Predictive information processing is a fundamental learning mechanism present in early development: evidence from infants.

    PubMed

    Trainor, Laurel J

    2012-02-01

    Evidence is presented that predictive coding is fundamental to brain function and present in early infancy. Indeed, mismatch responses to unexpected auditory stimuli are among the earliest robust cortical event-related potential responses, and have been measured in young infants in response to many types of deviation, including in pitch, timing, and melodic pattern. Furthermore, mismatch responses change quickly with specific experience, suggesting that predictive coding reflects a powerful, early-developing learning mechanism. Copyright © 2011 Elsevier B.V. All rights reserved.

  12. Three-dimensional integral imaging displays using a quick-response encoded elemental image array: an overview

    NASA Astrophysics Data System (ADS)

    Markman, A.; Javidi, B.

    2016-06-01

    Quick-response (QR) codes are barcodes that can store information such as numeric data and hyperlinks. The QR code can be scanned using a QR code reader, such as those built into smartphone devices, revealing the information stored in the code. Moreover, the QR code is robust to noise, rotation, and illumination when scanning due to error correction built in the QR code design. Integral imaging is an imaging technique used to generate a three-dimensional (3D) scene by combining the information from two-dimensional (2D) elemental images (EIs) each with a different perspective of a scene. Transferring these 2D images in a secure manner can be difficult. In this work, we overview two methods to store and encrypt EIs in multiple QR codes. The first method uses run-length encoding with Huffman coding and the double-random-phase encryption (DRPE) to compress and encrypt an EI. This information is then stored in a QR code. An alternative compression scheme is to perform photon-counting on the EI prior to compression. Photon-counting is a non-linear transformation of data that creates redundant information thus improving image compression. The compressed data is encrypted using the DRPE. Once information is stored in the QR codes, it is scanned using a smartphone device. The information scanned is decompressed and decrypted and an EI is recovered. Once all EIs have been recovered, a 3D optical reconstruction is generated.

  13. Teacher Candidates Implementing Universal Design for Learning: Enhancing Picture Books with QR Codes

    ERIC Educational Resources Information Center

    Grande, Marya; Pontrello, Camille

    2016-01-01

    The purpose of this study was to investigate if teacher candidates could gain knowledge of the principles of Universal Design for Learning by enhancing traditional picture books with Quick Response (QR) codes and to determine if the process of making these enhancements would impact teacher candidates' comfort levels with using technology on both…

  14. Evaluating QR Code Case Studies Using a Mobile Learning Framework

    ERIC Educational Resources Information Center

    Rikala, Jenni

    2014-01-01

    The aim of this study was to evaluate the feasibility of Quick Response (QR) codes and mobile devices in the context of Finnish basic education. The feasibility was analyzed through a mobile learning framework, which includes the core characteristics of mobile learning. The study is part of a larger research where the aim is to develop a…

  15. QR Codes: Taking Collections Further

    ERIC Educational Resources Information Center

    Ahearn, Caitlin

    2014-01-01

    With some thought and direction, QR (quick response) codes are a great tool to use in school libraries to enhance access to information. From March through April 2013, Caitlin Ahearn interned at Sanborn Regional High School (SRHS) under the supervision of Pam Harland. As a result of Harland's un-Deweying of the nonfiction collection at SRHS,…

  16. Genomics dataset of unidentified disclosed isolates.

    PubMed

    Rekadwad, Bhagwan N

    2016-09-01

    Analysis of DNA sequences is necessary for higher hierarchical classification of the organisms. It gives clues about the characteristics of organisms and their taxonomic position. This dataset is chosen to find complexities in the unidentified DNA in the disclosed patents. A total of 17 unidentified DNA sequences were thoroughly analyzed. The quick response codes were generated. AT/GC content of the DNA sequences analysis was carried out. The QR is helpful for quick identification of isolates. AT/GC content is helpful for studying their stability at different temperatures. Additionally, a dataset on cleavage code and enzyme code studied under the restriction digestion study, which helpful for performing studies using short DNA sequences was reported. The dataset disclosed here is the new revelatory data for exploration of unique DNA sequences for evaluation, identification, comparison and analysis.

  17. Information retrieval based on single-pixel optical imaging with quick-response code

    NASA Astrophysics Data System (ADS)

    Xiao, Yin; Chen, Wen

    2018-04-01

    Quick-response (QR) code technique is combined with ghost imaging (GI) to recover original information with high quality. An image is first transformed into a QR code. Then the QR code is treated as an input image in the input plane of a ghost imaging setup. After measurements, traditional correlation algorithm of ghost imaging is utilized to reconstruct an image (QR code form) with low quality. With this low-quality image as an initial guess, a Gerchberg-Saxton-like algorithm is used to improve its contrast, which is actually a post processing. Taking advantage of high error correction capability of QR code, original information can be recovered with high quality. Compared to the previous method, our method can obtain a high-quality image with comparatively fewer measurements, which means that the time-consuming postprocessing procedure can be avoided to some extent. In addition, for conventional ghost imaging, the larger the image size is, the more measurements are needed. However, for our method, images with different sizes can be converted into QR code with the same small size by using a QR generator. Hence, for the larger-size images, the time required to recover original information with high quality will be dramatically reduced. Our method makes it easy to recover a color image in a ghost imaging setup, because it is not necessary to divide the color image into three channels and respectively recover them.

  18. Investigating the use of quick response codes in the gross anatomy laboratory.

    PubMed

    Traser, Courtney J; Hoffman, Leslie A; Seifert, Mark F; Wilson, Adam B

    2015-01-01

    The use of quick response (QR) codes within undergraduate university courses is on the rise, yet literature concerning their use in medical education is scant. This study examined student perceptions on the usefulness of QR codes as learning aids in a medical gross anatomy course, statistically analyzed whether this learning aid impacted student performance, and evaluated whether performance could be explained by the frequency of QR code usage. Question prompts and QR codes tagged on cadaveric specimens and models were available for four weeks as learning aids to medical (n = 155) and doctor of physical therapy (n = 39) students. Each QR code provided answers to posed questions in the form of embedded text or hyperlinked web pages. Students' perceptions were gathered using a formative questionnaire and practical examination scores were used to assess potential gains in student achievement. Overall, students responded positively to the use of QR codes in the gross anatomy laboratory as 89% (57/64) agreed the codes augmented their learning of anatomy. The users' most noticeable objection to using QR codes was the reluctance to bring their smartphones into the gross anatomy laboratory. A comparison between the performance of QR code users and non-users was found to be nonsignificant (P = 0.113), and no significant gains in performance (P = 0.302) were observed after the intervention. Learners welcomed the implementation of QR code technology in the gross anatomy laboratory, yet this intervention had no apparent effect on practical examination performance. © 2014 American Association of Anatomists.

  19. Research and Trends in the Field of Technology-Enhanced Learning from 2006 to 2011: A Content Analysis of Quick Response Code (QR-Code) and Its Application in Selected Studies

    ERIC Educational Resources Information Center

    Hau, Goh Bak; Siraj, Saedah; Alias, Norlidah; Rauf, Rose Amnah Abd.; Zakaria, Abd. Razak; Darusalam, Ghazali

    2013-01-01

    This study provides a content analysis of selected articles in the field of QR code and its application in educational context that were published in journals and proceedings of international conferences and workshops from 2006 to 2011. These articles were cross analysed by published years, journal, and research topics. Further analysis was…

  20. Testing Quick Response (QR) Codes as an Innovation to Improve Feedback Among Geographically-Separated Clerkship Sites.

    PubMed

    Snyder, Matthew J; Nguyen, Dana R; Womack, Jasmyne J; Bunt, Christopher W; Westerfield, Katie L; Bell, Adriane E; Ledford, Christy J W

    2018-03-01

    Collection of feedback regarding medical student clinical experiences for formative or summative purposes remains a challenge across clinical settings. The purpose of this study was to determine whether the use of a quick response (QR) code-linked online feedback form improves the frequency and efficiency of rater feedback. In 2016, we compared paper-based feedback forms, an online feedback form, and a QR code-linked online feedback form at 15 family medicine clerkship sites across the United States. Outcome measures included usability, number of feedback submissions per student, number of unique raters providing feedback, and timeliness of feedback provided to the clerkship director. The feedback method was significantly associated with usability, with QR code scoring the highest, and paper second. Accessing feedback via QR code was associated with the shortest time to prepare feedback. Across four rotations, separate repeated measures analyses of variance showed no effect of feedback system on the number of submissions per student or the number of unique raters. The results of this study demonstrate that preceptors in the family medicine clerkship rate QR code-linked feedback as a high usability platform. Additionally, this platform resulted in faster form completion than paper or online forms. An overarching finding of this study is that feedback forms must be portable and easily accessible. Potential implementation barriers and the social norm for providing feedback in this manner need to be considered.

  1. Security authentication using phase-encoded nanoparticle structures and polarized light.

    PubMed

    Carnicer, Artur; Hassanfiroozi, Amir; Latorre-Carmona, Pedro; Huang, Yi-Pai; Javidi, Bahram

    2015-01-15

    Phase-encoded nanostructures such as quick response (QR) codes made of metallic nanoparticles are suggested to be used in security and authentication applications. We present a polarimetric optical method able to authenticate random phase-encoded QR codes. The system is illuminated using polarized light, and the QR code is encoded using a phase-only random mask. Using classification algorithms, it is possible to validate the QR code from the examination of the polarimetric signature of the speckle pattern. We used Kolmogorov-Smirnov statistical test and Support Vector Machine algorithms to authenticate the phase-encoded QR codes using polarimetric signatures.

  2. Security printing of covert quick response codes using upconverting nanoparticle inks

    NASA Astrophysics Data System (ADS)

    Meruga, Jeevan M.; Cross, William M.; May, P. Stanley; Luu, QuocAnh; Crawford, Grant A.; Kellar, Jon J.

    2012-10-01

    Counterfeiting costs governments and private industries billions of dollars annually due to loss of value in currency and other printed items. This research involves using lanthanide doped β-NaYF4 nanoparticles for security printing applications. Inks comprised of Yb3+/Er3+ and Yb3+/Tm3+ doped β-NaYF4 nanoparticles with oleic acid as the capping agent in toluene and methyl benzoate with poly(methyl methacrylate) (PMMA) as the binding agent were used to print quick response (QR) codes. The QR codes were made using an AutoCAD file and printed with Optomec direct-write aerosol jetting®. The printed QR codes are invisible under ambient lighting conditions, but are readable using a near-IR laser, and were successfully scanned using a smart phone. This research demonstrates that QR codes, which have been used primarily for information sharing applications, can also be used for security purposes. Higher levels of security were achieved by printing both green and blue upconverting inks, based on combinations of Er3+/Yb3+ and Tm3+/Yb3+, respectively, in a single QR code. The near-infrared (NIR)-to-visible upconversion luminescence properties of the two-ink QR codes were analyzed, including the influence of NIR excitation power density on perceived color, in term of the CIE 1931 chromaticity index. It was also shown that this security ink can be optimized for line width, thickness and stability on different substrates.

  3. Security printing of covert quick response codes using upconverting nanoparticle inks.

    PubMed

    Meruga, Jeevan M; Cross, William M; Stanley May, P; Luu, QuocAnh; Crawford, Grant A; Kellar, Jon J

    2012-10-05

    Counterfeiting costs governments and private industries billions of dollars annually due to loss of value in currency and other printed items. This research involves using lanthanide doped β-NaYF(4) nanoparticles for security printing applications. Inks comprised of Yb(3+)/Er(3+) and Yb(3+)/Tm(3+) doped β-NaYF(4) nanoparticles with oleic acid as the capping agent in toluene and methyl benzoate with poly(methyl methacrylate) (PMMA) as the binding agent were used to print quick response (QR) codes. The QR codes were made using an AutoCAD file and printed with Optomec direct-write aerosol jetting(®). The printed QR codes are invisible under ambient lighting conditions, but are readable using a near-IR laser, and were successfully scanned using a smart phone. This research demonstrates that QR codes, which have been used primarily for information sharing applications, can also be used for security purposes. Higher levels of security were achieved by printing both green and blue upconverting inks, based on combinations of Er(3+)/Yb(3+) and Tm(3+)/Yb(3+), respectively, in a single QR code. The near-infrared (NIR)-to-visible upconversion luminescence properties of the two-ink QR codes were analyzed, including the influence of NIR excitation power density on perceived color, in term of the CIE 1931 chromaticity index. It was also shown that this security ink can be optimized for line width, thickness and stability on different substrates.

  4. Quick Response codes for surgical safety: a prospective pilot study.

    PubMed

    Dixon, Jennifer L; Smythe, William Roy; Momsen, Lara S; Jupiter, Daniel; Papaconstantinou, Harry T

    2013-09-01

    Surgical safety programs have been shown to reduce patient harm; however, there is variable compliance. The purpose of this study is to determine if innovative technology such as Quick Response (QR) codes can facilitate surgical safety initiatives. We prospectively evaluated the use of QR codes during the surgical time-out for 40 operations. Feasibility and accuracy were assessed. Perceptions of the current time-out process and the QR code application were evaluated through surveys using a 5-point Likert scale and binomial yes or no questions. At baseline (n = 53), survey results from the surgical team agreed or strongly agreed that the current time-out process was efficient (64%), easy to use (77%), and provided clear information (89%). However, 65% of surgeons felt that process improvements were needed. Thirty-seven of 40 (92.5%) QR codes scanned successfully, of which 100% were accurate. Three scan failures resulted from excessive curvature or wrinkling of the QR code label on the body. Follow-up survey results (n = 33) showed that the surgical team agreed or strongly agreed that the QR program was clearer (70%), easier to use (57%), and more accurate (84%). Seventy-four percent preferred the QR system to the current time-out process. QR codes accurately transmit patient information during the time-out procedure and are preferred to the current process by surgical team members. The novel application of this technology may improve compliance, accuracy, and outcomes. Copyright © 2013 Elsevier Inc. All rights reserved.

  5. Research on pre-processing of QR Code

    NASA Astrophysics Data System (ADS)

    Sun, Haixing; Xia, Haojie; Dong, Ning

    2013-10-01

    QR code encodes many kinds of information because of its advantages: large storage capacity, high reliability, full arrange of utter-high-speed reading, small printing size and high-efficient representation of Chinese characters, etc. In order to obtain the clearer binarization image from complex background, and improve the recognition rate of QR code, this paper researches on pre-processing methods of QR code (Quick Response Code), and shows algorithms and results of image pre-processing for QR code recognition. Improve the conventional method by changing the Souvola's adaptive text recognition method. Additionally, introduce the QR code Extraction which adapts to different image size, flexible image correction approach, and improve the efficiency and accuracy of QR code image processing.

  6. Technical Modification Within the Healthcare Industry: Improving Both the Efficacy of the National Drug Code Carrier and the Accessibility of Electronic Health Records to Reduce Adverse Drug Events

    DTIC Science & Technology

    2013-06-01

    with an EHR .................................................. 97 C. SWOT ANALYSIS OF USING QR CODES WITH THE NDC AND WITH EHRS...96 Figure 41. SWOT analysis ................................................................................... 99 xiii LIST OF...Coordinator for Health Information Technology OTC Over-the-Counter PHI Personal Health Information QR Quick Response SWOT Strengths, Weaknesses

  7. Roots of success: Marketing strategies for the 21st Century

    Treesearch

    Ian Doescher

    2012-01-01

    As the demographic of gardeners and farmers changes, retail nurseries should update their marketing approach. This paper reviews best marketing practices and discusses marketing technologies, including quick response (QR) codes, websites, online marketing, and social media.

  8. Optical encryption of digital data in form of quick response code using spatially incoherent illumination

    NASA Astrophysics Data System (ADS)

    Cheremkhin, Pavel A.; Krasnov, Vitaly V.; Rodin, Vladislav G.; Starikov, Rostislav S.

    2016-11-01

    Applications of optical methods for encryption purposes have been attracting interest of researchers for decades. The most popular are coherent techniques such as double random phase encoding. Its main advantage is high security due to transformation of spectrum of image to be encrypted into white spectrum via use of first phase random mask which allows for encrypted images with white spectra. Downsides are necessity of using holographic registration scheme and speckle noise occurring due to coherent illumination. Elimination of these disadvantages is possible via usage of incoherent illumination. In this case, phase registration no longer matters, which means that there is no need for holographic setup, and speckle noise is gone. Recently, encryption of digital information in form of binary images has become quite popular. Advantages of using quick response (QR) code in capacity of data container for optical encryption include: 1) any data represented as QR code will have close to white (excluding zero spatial frequency) Fourier spectrum which have good overlapping with encryption key spectrum; 2) built-in algorithm for image scale and orientation correction which simplifies decoding of decrypted QR codes; 3) embedded error correction code allows for successful decryption of information even in case of partial corruption of decrypted image. Optical encryption of digital data in form QR codes using spatially incoherent illumination was experimentally implemented. Two liquid crystal spatial light modulators were used in experimental setup for QR code and encrypting kinoform imaging respectively. Decryption was conducted digitally. Successful decryption of encrypted QR codes is demonstrated.

  9. Three-dimensional quick response code based on inkjet printing of upconversion fluorescent nanoparticles for drug anti-counterfeiting.

    PubMed

    You, Minli; Lin, Min; Wang, Shurui; Wang, Xuemin; Zhang, Ge; Hong, Yuan; Dong, Yuqing; Jin, Guorui; Xu, Feng

    2016-05-21

    Medicine counterfeiting is a serious issue worldwide, involving potentially devastating health repercussions. Advanced anti-counterfeit technology for drugs has therefore aroused intensive interest. However, existing anti-counterfeit technologies are associated with drawbacks such as the high cost, complex fabrication process, sophisticated operation and incapability in authenticating drug ingredients. In this contribution, we developed a smart phone recognition based upconversion fluorescent three-dimensional (3D) quick response (QR) code for tracking and anti-counterfeiting of drugs. We firstly formulated three colored inks incorporating upconversion nanoparticles with RGB (i.e., red, green and blue) emission colors. Using a modified inkjet printer, we printed a series of colors by precisely regulating the overlap of these three inks. Meanwhile, we developed a multilayer printing and splitting technology, which significantly increases the information storage capacity per unit area. As an example, we directly printed the upconversion fluorescent 3D QR code on the surface of drug capsules. The 3D QR code consisted of three different color layers with each layer encoded by information of different aspects of the drug. A smart phone APP was designed to decode the multicolor 3D QR code, providing the authenticity and related information of drugs. The developed technology possesses merits in terms of low cost, ease of operation, high throughput and high information capacity, thus holds great potential for drug anti-counterfeiting.

  10. Is QR code an optimal data container in optical encryption systems from an error-correction coding perspective?

    PubMed

    Jiao, Shuming; Jin, Zhi; Zhou, Changyuan; Zou, Wenbin; Li, Xia

    2018-01-01

    Quick response (QR) code has been employed as a data carrier for optical cryptosystems in many recent research works, and the error-correction coding mechanism allows the decrypted result to be noise free. However, in this paper, we point out for the first time that the Reed-Solomon coding algorithm in QR code is not a very suitable option for the nonlocally distributed speckle noise in optical cryptosystems from an information coding perspective. The average channel capacity is proposed to measure the data storage capacity and noise-resistant capability of different encoding schemes. We design an alternative 2D barcode scheme based on Bose-Chaudhuri-Hocquenghem (BCH) coding, which demonstrates substantially better average channel capacity than QR code in numerical simulated optical cryptosystems.

  11. Investigating the feasibility of using quick response codes in highway construction for document control.

    DOT National Transportation Integrated Search

    2015-07-01

    Highway construction takes place in remote locations, making document control challenging. Frequent changes in a project can cause errors, : reworks, and schedule delays due to the time taken to disseminate these changes to the field or due to using ...

  12. Quick reproduction of blast-wave flow-field properties of nuclear, TNT, and ANFO explosions

    NASA Astrophysics Data System (ADS)

    Groth, C. P. T.

    1986-04-01

    In many instances, extensive blast-wave flow-field properties are required in gasdynamics research studies of blast-wave loading and structure response, and in evaluating the effects of explosions on their environment. This report provides a very useful computer code, which can be used in conjunction with the DNA Nuclear Blast Standard subroutines and code, to quickly reconstruct complete and fairly accurate blast-wave data for almost any free-air (spherical) and surface-burst (hemispherical) nuclear, trinitrotoluene (TNT), or ammonium nitrate-fuel oil (ANFO) explosion. This code is capable of computing all of the main flow properties as functions of radius and time, as well as providing additional information regarding air viscosity, reflected shock-wave properties, and the initial decay of the flow properties just behind the shock front. Both spatial and temporal distributions of the major blast-wave flow properties are also made readily available. Finally, provisions are also included in the code to provide additional information regarding the peak or shock-front flow properties over a range of radii, for a specific explosion of interest.

  13. Web Card - Clean Cities Plug-In Electric Vehicle Handbook for Public Charging Station Hosts

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    A 2" x 3-1/4" web card which has a quick response code for accessing the PEV Handbook for Public Charging Station Hosts via a smart phone. The cards are intended to be handed out instead of the handbook.

  14. International Quick Response Forces

    DTIC Science & Technology

    1994-06-06

    RESPONSIBLE INDIVIDUAL 22b. TELEPHONE (include Area Code) 22c O;FICE SYMBOL PROFE SOR JOHN B. HATTENDORF (401)8641 i13i 35 DD Form 1473. JUN 86...sooner - therein lies the utility of rapid response forces. 42 John F. Burns, "UN Peacekeeping Moves into Yugoslavia," The New York Times, March 15...more challenging and more resource intensive it becomes.44 - GEN John Shalikashvili Chairman, Joint Chiefs of Staff former Supreme Allied Commander

  15. A Comprehensive Structural Dynamic Analysis Approach for Multi Mission Earth Entry Vehicle (MMEEV) Development

    NASA Technical Reports Server (NTRS)

    Perino, Scott; Bayandor, Javid; Siddens, Aaron

    2012-01-01

    The anticipated NASA Mars Sample Return Mission (MSR) requires a simple and reliable method in which to return collected Martian samples back to earth for scientific analysis. The Multi-Mission Earth Entry Vehicle (MMEEV) is NASA's proposed solution to this MSR requirement. Key aspects of the MMEEV are its reliable and passive operation, energy absorbing foam-composite structure, and modular impact sphere (IS) design. To aid in the development of an EEV design that can be modified for various missions requirements, two fully parametric finite element models were developed. The first model was developed in an explicit finite element code and was designed to evaluate the impact response of the vehicle and payload during the final stage of the vehicle's return to earth. The second model was developed in an explicit code and was designed to evaluate the static and dynamic structural response of the vehicle during launch and reentry. In contrast to most other FE models, built through a Graphical User Interface (GUI) pre-processor, the current model was developed using a coding technique that allows the analyst to quickly change nearly all aspects of the model including: geometric dimensions, material properties, load and boundary conditions, mesh properties, and analysis controls. Using the developed design tool, a full range of proposed designs can quickly be analyzed numerically and thus the design trade space for the EEV can be fully understood. An engineer can then quickly reach the best design for a specific mission and also adapt and optimize the general design for different missions.

  16. Three-dimensional quick response code based on inkjet printing of upconversion fluorescent nanoparticles for drug anti-counterfeiting

    NASA Astrophysics Data System (ADS)

    You, Minli; Lin, Min; Wang, Shurui; Wang, Xuemin; Zhang, Ge; Hong, Yuan; Dong, Yuqing; Jin, Guorui; Xu, Feng

    2016-05-01

    Medicine counterfeiting is a serious issue worldwide, involving potentially devastating health repercussions. Advanced anti-counterfeit technology for drugs has therefore aroused intensive interest. However, existing anti-counterfeit technologies are associated with drawbacks such as the high cost, complex fabrication process, sophisticated operation and incapability in authenticating drug ingredients. In this contribution, we developed a smart phone recognition based upconversion fluorescent three-dimensional (3D) quick response (QR) code for tracking and anti-counterfeiting of drugs. We firstly formulated three colored inks incorporating upconversion nanoparticles with RGB (i.e., red, green and blue) emission colors. Using a modified inkjet printer, we printed a series of colors by precisely regulating the overlap of these three inks. Meanwhile, we developed a multilayer printing and splitting technology, which significantly increases the information storage capacity per unit area. As an example, we directly printed the upconversion fluorescent 3D QR code on the surface of drug capsules. The 3D QR code consisted of three different color layers with each layer encoded by information of different aspects of the drug. A smart phone APP was designed to decode the multicolor 3D QR code, providing the authenticity and related information of drugs. The developed technology possesses merits in terms of low cost, ease of operation, high throughput and high information capacity, thus holds great potential for drug anti-counterfeiting.Medicine counterfeiting is a serious issue worldwide, involving potentially devastating health repercussions. Advanced anti-counterfeit technology for drugs has therefore aroused intensive interest. However, existing anti-counterfeit technologies are associated with drawbacks such as the high cost, complex fabrication process, sophisticated operation and incapability in authenticating drug ingredients. In this contribution, we developed a smart phone recognition based upconversion fluorescent three-dimensional (3D) quick response (QR) code for tracking and anti-counterfeiting of drugs. We firstly formulated three colored inks incorporating upconversion nanoparticles with RGB (i.e., red, green and blue) emission colors. Using a modified inkjet printer, we printed a series of colors by precisely regulating the overlap of these three inks. Meanwhile, we developed a multilayer printing and splitting technology, which significantly increases the information storage capacity per unit area. As an example, we directly printed the upconversion fluorescent 3D QR code on the surface of drug capsules. The 3D QR code consisted of three different color layers with each layer encoded by information of different aspects of the drug. A smart phone APP was designed to decode the multicolor 3D QR code, providing the authenticity and related information of drugs. The developed technology possesses merits in terms of low cost, ease of operation, high throughput and high information capacity, thus holds great potential for drug anti-counterfeiting. Electronic supplementary information (ESI) available: Calculating details of UCNP content per 3D QR code and decoding process of the 3D QR code. See DOI: 10.1039/c6nr01353h

  17. Interactive QR code beautification with full background image embedding

    NASA Astrophysics Data System (ADS)

    Lin, Lijian; Wu, Song; Liu, Sijiang; Jiang, Bo

    2017-06-01

    QR (Quick Response) code is a kind of two dimensional barcode that was first developed in automotive industry. Nowadays, QR code has been widely used in commercial applications like product promotion, mobile payment, product information management, etc. Traditional QR codes in accordance with the international standard are reliable and fast to decode, but are lack of aesthetic appearance to demonstrate visual information to customers. In this work, we present a novel interactive method to generate aesthetic QR code. By given information to be encoded and an image to be decorated as full QR code background, our method accepts interactive user's strokes as hints to remove undesired parts of QR code modules based on the support of QR code error correction mechanism and background color thresholds. Compared to previous approaches, our method follows the intention of the QR code designer, thus can achieve more user pleasant result, while keeping high machine readability.

  18. Security authentication with a three-dimensional optical phase code using random forest classifier: an overview

    NASA Astrophysics Data System (ADS)

    Markman, Adam; Carnicer, Artur; Javidi, Bahram

    2017-05-01

    We overview our recent work [1] on utilizing three-dimensional (3D) optical phase codes for object authentication using the random forest classifier. A simple 3D optical phase code (OPC) is generated by combining multiple diffusers and glass slides. This tag is then placed on a quick-response (QR) code, which is a barcode capable of storing information and can be scanned under non-uniform illumination conditions, rotation, and slight degradation. A coherent light source illuminates the OPC and the transmitted light is captured by a CCD to record the unique signature. Feature extraction on the signature is performed and inputted into a pre-trained random-forest classifier for authentication.

  19. Raman spectroscopy: in vivo quick response code of skin physiological status

    NASA Astrophysics Data System (ADS)

    Vyumvuhore, Raoul; Tfayli, Ali; Piot, Olivier; Le Guillou, Maud; Guichard, Nathalie; Manfait, Michel; Baillet-Guffroy, Arlette

    2014-11-01

    Dermatologists need to combine different clinically relevant characteristics for a better understanding of skin health. These characteristics are usually measured by different techniques, and some of them are highly time consuming. Therefore, a predicting model based on Raman spectroscopy and partial least square (PLS) regression was developed as a rapid multiparametric method. The Raman spectra collected from the five uppermost micrometers of 11 healthy volunteers were fitted to different skin characteristics measured by independent appropriate methods (transepidermal water loss, hydration, pH, relative amount of ceramides, fatty acids, and cholesterol). For each parameter, the obtained PLS model presented correlation coefficients higher than R2=0.9. This model enables us to obtain all the aforementioned parameters directly from the unique Raman signature. In addition to that, in-depth Raman analyses down to 20 μm showed different balances between partially bound water and unbound water with depth. In parallel, the increase of depth was followed by an unfolding process of the proteins. The combinations of all these information led to a multiparametric investigation, which better characterizes the skin status. Raman signal can thus be used as a quick response code (QR code). This could help dermatologic diagnosis of physiological variations and presents a possible extension to pathological characterization.

  20. Raman spectroscopy: in vivo quick response code of skin physiological status.

    PubMed

    Vyumvuhore, Raoul; Tfayli, Ali; Piot, Olivier; Le Guillou, Maud; Guichard, Nathalie; Manfait, Michel; Baillet-Guffroy, Arlette

    2014-01-01

    Dermatologists need to combine different clinically relevant characteristics for a better understanding of skin health. These characteristics are usually measured by different techniques, and some of them are highly time consuming. Therefore, a predicting model based on Raman spectroscopy and partial least square (PLS) regression was developed as a rapid multiparametric method. The Raman spectra collected from the five uppermost micrometers of 11 healthy volunteers were fitted to different skin characteristics measured by independent appropriate methods (transepidermal water loss, hydration, pH, relative amount of ceramides, fatty acids, and cholesterol). For each parameter, the obtained PLS model presented correlation coefficients higher than R2=0.9. This model enables us to obtain all the aforementioned parameters directly from the unique Raman signature. In addition to that, in-depth Raman analyses down to 20 μm showed different balances between partially bound water and unbound water with depth. In parallel, the increase of depth was followed by an unfolding process of the proteins. The combinations of all these information led to a multiparametric investigation, which better characterizes the skin status. Raman signal can thus be used as a quick response code (QR code). This could help dermatologic diagnosis of physiological variations and presents a possible extension to pathological characterization.

  1. [INVITED] Luminescent QR codes for smart labelling and sensing

    NASA Astrophysics Data System (ADS)

    Ramalho, João F. C. B.; António, L. C. F.; Correia, S. F. H.; Fu, L. S.; Pinho, A. S.; Brites, C. D. S.; Carlos, L. D.; André, P. S.; Ferreira, R. A. S.

    2018-05-01

    QR (Quick Response) codes are two-dimensional barcodes composed of special geometric patterns of black modules in a white square background that can encode different types of information with high density and robustness, correct errors and physical damages, thus keeping the stored information protected. Recently, these codes have gained increased attention as they offer a simple physical tool for quick access to Web sites for advertising and social interaction. Challenges encompass the increase of the storage capacity limit, even though they can store approximately 350 times more information than common barcodes, and encode different types of characters (e.g., numeric, alphanumeric, kanji and kana). In this work, we fabricate luminescent QR codes based on a poly(methyl methacrylate) substrate coated with organic-inorganic hybrid materials doped with trivalent terbium (Tb3+) and europium (Eu3+) ions, demonstrating the increase of storage capacity per unit area by a factor of two by using the colour multiplexing, when compared to conventional QR codes. A novel methodology to decode the multiplexed QR codes is developed based on a colour separation threshold where a decision level is calculated through a maximum-likelihood criteria to minimize the error probability of the demultiplexed modules, maximizing the foreseen total storage capacity. Moreover, the thermal dependence of the emission colour coordinates of the Eu3+/Tb3+-based hybrids enables the simultaneously QR code colour-multiplexing and may be used to sense temperature (reproducibility higher than 93%), opening new fields of applications for QR codes as smart labels for sensing.

  2. QR Codes in the Library: "It's Not Your Mother's Barcode!"

    ERIC Educational Resources Information Center

    Dobbs, Cheri

    2011-01-01

    Barcode scanning has become more than just fun. Now libraries and businesses are leveraging barcode technology as an innovative tool to market their products and ideas. Developed and popularized in Japan, these Quick Response (QR) or two-dimensional barcodes allow marketers to provide interactive content in an otherwise static environment. In this…

  3. Optical image encryption based on real-valued coding and subtracting with the help of QR code

    NASA Astrophysics Data System (ADS)

    Deng, Xiaopeng

    2015-08-01

    A novel optical image encryption based on real-valued coding and subtracting is proposed with the help of quick response (QR) code. In the encryption process, the original image to be encoded is firstly transformed into the corresponding QR code, and then the corresponding QR code is encoded into two phase-only masks (POMs) by using basic vector operations. Finally, the absolute values of the real or imaginary parts of the two POMs are chosen as the ciphertexts. In decryption process, the QR code can be approximately restored by recording the intensity of the subtraction between the ciphertexts, and hence the original image can be retrieved without any quality loss by scanning the restored QR code with a smartphone. Simulation results and actual smartphone collected results show that the method is feasible and has strong tolerance to noise, phase difference and ratio between intensities of the two decryption light beams.

  4. Tools for Designing and Analyzing Structures

    NASA Technical Reports Server (NTRS)

    Luz, Paul L.

    2005-01-01

    Structural Design and Analysis Toolset is a collection of approximately 26 Microsoft Excel spreadsheet programs, each of which performs calculations within a different subdiscipline of structural design and analysis. These programs present input and output data in user-friendly, menu-driven formats. Although these programs cannot solve complex cases like those treated by larger finite element codes, these programs do yield quick solutions to numerous common problems more rapidly than the finite element codes, thereby making it possible to quickly perform multiple preliminary analyses - e.g., to establish approximate limits prior to detailed analyses by the larger finite element codes. These programs perform different types of calculations, as follows: 1. determination of geometric properties for a variety of standard structural components; 2. analysis of static, vibrational, and thermal- gradient loads and deflections in certain structures (mostly beams and, in the case of thermal-gradients, mirrors); 3. kinetic energies of fans; 4. detailed analysis of stress and buckling in beams, plates, columns, and a variety of shell structures; and 5. temperature dependent properties of materials, including figures of merit that characterize strength, stiffness, and deformation response to thermal gradients

  5. Embed dynamic content in your poster.

    PubMed

    Hutchins, B Ian

    2013-01-29

    A new technology has emerged that will facilitate the presentation of dynamic or otherwise inaccessible data on posters at scientific meetings. Video, audio, or other digital files hosted on mobile-friendly sites can be linked to through a quick response (QR) code, a two-dimensional barcode that can be scanned by smartphones, which then display the content. This approach is more affordable than acquiring tablet computers for playing dynamic content and can reach many users at large conferences. This resource details how to host videos, generate QR codes, and view the associated files on mobile devices.

  6. The Effectiveness of Using Procedural Scaffoldings in a Paper-Plus-Smartphone Collaborative Learning Context

    ERIC Educational Resources Information Center

    Huang, Hui-Wen; Wu, Chih-Wei; Chen, Nian-Shing

    2012-01-01

    The purpose of this study was to evaluate the effectiveness of using procedural scaffoldings in fostering students' group discourse levels and learning outcomes in a paper-plus-smartphone collaborative learning context. All participants used built-in camera smartphones to learn new knowledge by scanning Quick Response (QR) codes, a type of…

  7. Optical image encryption using QR code and multilevel fingerprints in gyrator transform domains

    NASA Astrophysics Data System (ADS)

    Wei, Yang; Yan, Aimin; Dong, Jiabin; Hu, Zhijuan; Zhang, Jingtao

    2017-11-01

    A new concept of GT encryption scheme is proposed in this paper. We present a novel optical image encryption method by using quick response (QR) code and multilevel fingerprint keys in gyrator transform (GT) domains. In this method, an original image is firstly transformed into a QR code, which is placed in the input plane of cascaded GTs. Subsequently, the QR code is encrypted into the cipher-text by using multilevel fingerprint keys. The original image can be obtained easily by reading the high-quality retrieved QR code with hand-held devices. The main parameters used as private keys are GTs' rotation angles and multilevel fingerprints. Biometrics and cryptography are integrated with each other to improve data security. Numerical simulations are performed to demonstrate the validity and feasibility of the proposed encryption scheme. In the future, the method of applying QR codes and fingerprints in GT domains possesses much potential for information security.

  8. Leveraging Quick Response Code Technology to Facilitate Simulation-Based Leaderboard Competition.

    PubMed

    Chang, Todd P; Doughty, Cara B; Mitchell, Diana; Rutledge, Chrystal; Auerbach, Marc A; Frisell, Karin; Jani, Priti; Kessler, David O; Wolfe, Heather; MacKinnon, Ralph J; Dewan, Maya; Pirie, Jonathan; Lemke, Daniel; Khattab, Mona; Tofil, Nancy; Nagamuthu, Chenthila; Walsh, Catharine M

    2018-02-01

    Leaderboards provide feedback on relative performance and a competitive atmosphere for both self-guided improvement and social comparison. Because simulation can provide substantial quantitative participant feedback, leaderboards can be used, not only locally but also in a multidepartment, multicenter fashion. Quick Response (QR) codes can be integrated to allow participants to access and upload data. We present the development, implementation, and initial evaluation of an online leaderboard employing principles of gamification using points, badges, and leaderboards designed to enhance competition among healthcare providers. This article details the fundamentals behind the development and implementation of a user-friendly, online, multinational leaderboard that employs principles of gamification to enhance competition and integrates a QR code system to promote both self-reporting of performance data and data integrity. An open-ended survey was administered to capture perceptions of leaderboard implementation. Conceptual step-by-step instructions detailing how to apply the QR code system to any leaderboard using simulated or real performance metrics are outlined using an illustrative example of a leaderboard that employed simulated cardiopulmonary resuscitation performance scores to compare participants across 17 hospitals in 4 countries for 16 months. The following three major descriptive categories that captured perceptions of leaderboard implementation emerged from initial evaluation data from 10 sites: (1) competition, (2) longevity, and (3) perceived deficits. A well-designed leaderboard should be user-friendly and encompass best practices in gamification principles while collecting and storing data for research analyses. Easy storage and export of data allow for longitudinal record keeping that can be leveraged both to track compliance and to enable social competition.

  9. Brief Pictorial Description of New Mobile Technologies Used in Cultural Institutions in Japan

    ERIC Educational Resources Information Center

    Awano, Yumi

    2007-01-01

    Many Japanese museums and other cultural institutions have been exploring ways to enrich visitors' experiences using new digital devices. This paper briefly describes some examples in Japan, ranging from a PDA, a mobile phone, podcasting, and an audio guide speaker-equipped vest to a Quick Response (QR) code on a brochure for downloading a short…

  10. Photoactive Self-Shaping Hydrogels as Noncontact 3D Macro/Microscopic Photoprinting Platforms.

    PubMed

    Liao, Yue; An, Ning; Wang, Ning; Zhang, Yinyu; Song, Junfei; Zhou, Jinxiong; Liu, Wenguang

    2015-12-01

    A photocleavable terpolymer hydrogel cross-linked with o-nitrobenzyl derivative cross-linker is shown to be capable of self-shaping without losing its physical integrity and robustness due to spontaneous asymmetric swelling of network caused by UV-light-induced gradient cleavage of chemical cross-linkages. The continuum model and finite element method are used to elucidate the curling mechanism underlying. Remarkably, based on the self-changing principle, the photosensitive hydrogels can be developed as photoprinting soft and wet platforms onto which specific 3D characters and images are faithfully duplicated in macro/microscale without contact by UV light irradiation under the cover of customized photomasks. Importantly, a quick response (QR) code is accurately printed on the photoactive hydrogel for the first time. Scanning QR code with a smartphone can quickly connect to a web page. This photoactive hydrogel is promising to be a new printing or recording material. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  11. Collaborative Research: Simulation of Beam-Electron Cloud Interactions in Circular Accelerators Using Plasma Models

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Katsouleas, Thomas; Decyk, Viktor

    Final Report for grant DE-FG02-06ER54888, "Simulation of Beam-Electron Cloud Interactions in Circular Accelerators Using Plasma Models" Viktor K. Decyk, University of California, Los Angeles Los Angeles, CA 90095-1547 The primary goal of this collaborative proposal was to modify the code QuickPIC and apply it to study the long-time stability of beam propagation in low density electron clouds present in circular accelerators. The UCLA contribution to this collaborative proposal was in supporting the development of the pipelining scheme for the QuickPIC code, which extended the parallel scaling of this code by two orders of magnitude. The USC work was as describedmore » here the PhD research for Ms. Bing Feng, lead author in reference 2 below, who performed the research at USC under the guidance of the PI Tom Katsouleas and the collaboration of Dr. Decyk The QuickPIC code [1] is a multi-scale Particle-in-Cell (PIC) code. The outer 3D code contains a beam which propagates through a long region of plasma and evolves slowly. The plasma response to this beam is modeled by slices of a 2D plasma code. This plasma response then is fed back to the beam code, and the process repeats. The pipelining is based on the observation that once the beam has passed a 2D slice, its response can be fed back to the beam immediately without waiting for the beam to pass all the other slices. Thus independent blocks of 2D slices from different time steps can be running simultaneously. The major difficulty was when particles at the edges needed to communicate with other blocks. Two versions of the pipelining scheme were developed, for the the full quasi-static code and the other for the basic quasi-static code used by this e-cloud proposal. Details of the pipelining scheme were published in [2]. The new version of QuickPIC was able to run with more than 1,000 processors, and was successfully applied in modeling e-clouds by our collaborators in this proposal [3-8]. Jean-Luc Vay at Lawrence Berkeley National Lab later implemented a similar basic quasistatic scheme including pipelining in the code WARP [9] and found good to very good quantitative agreement between the two codes in modeling e-clouds. References [1] C. Huang, V. K. Decyk, C. Ren, M. Zhou, W. Lu, W. B. Mori, J. H. Cooley, T. M. Antonsen, Jr., and T. Katsouleas, "QUICKPIC: A highly efficient particle-in-cell code for modeling wakefield acceleration in plasmas," J. Computational Phys. 217, 658 (2006). [2] B. Feng, C. Huang, V. K. Decyk, W. B. Mori, P. Muggli, and T. Katsouleas, "Enhancing parallel quasi-static particle-in-cell simulations with a pipelining algorithm," J. Computational Phys, 228, 5430 (2009). [3] C. Huang, V. K. Decyk, M. Zhou, W. Lu, W. B. Mori, J. H. Cooley, T. M. Antonsen, Jr., and B. Feng, T. Katsouleas, J. Vieira, and L. O. Silva, "QUICKPIC: A highly efficient fully parallelized PIC code for plasma-based acceleration," Proc. of the SciDAC 2006 Conf., Denver, Colorado, June, 2006 [Journal of Physics: Conference Series, W. M. Tang, Editor, vol. 46, Institute of Physics, Bristol and Philadelphia, 2006], p. 190. [4] B. Feng, C. Huang, V. Decyk, W. B. Mori, T. Katsouleas, P. Muggli, "Enhancing Plasma Wakefield and E-cloud Simulation Performance Using a Pipelining Algorithm," Proc. 12th Workshop on Advanced Accelerator Concepts, Lake Geneva, WI, July, 2006, p. 201 [AIP Conf. Proceedings, vol. 877, Melville, NY, 2006]. [5] B. Feng, P. Muggli, T. Katsouleas, V. Decyk, C. Huang, and W. Mori, "Long Time Electron Cloud Instability Simulation Using QuickPIC with Pipelining Algorithm," Proc. of the 2007 Particle Accelerator Conference, Albuquerque, NM, June, 2007, p. 3615. [6] B. Feng, C. Huang, V. Decyk, W. B. Mori, G. H. Hoffstaetter, P. Muggli, T. Katsouleas, "Simulation of Electron Cloud Effects on Electron Beam at ERL with Pipelined QuickPIC," Proc. 13th Workshop on Advanced Accelerator Concepts, Santa Cruz, CA, July-August, 2008, p. 340 [AIP Conf. Proceedings, vol. 1086, Melville, NY, 2008]. [7] B. Feng, C. Huang, V. K. Decyk, W. B. Mori, P. Muggli, and T. Katsouleas, "Enhancing parallel quasi-static particle-in-cell simulations with a pipelining algorithm," J. Computational Phys, 228, 5430 (2009). [8] C. Huang, W. An, V. K. Decyk, W. Lu, W. B. Mori, F. S. Tsung, M. Tzoufras, S. Morshed, T. Antonsen, B. Feng, T. Katsouleas, R., A. Fonseca, S. F. Martins, J. Vieira, L. O. Silva, E. Esarey, C. G. R. Geddes, W. P. Leemans, E. Cormier-Michel, J.-L. Vay, D. L. Bruhwiler, B. Cowan, J. R. Cary, and K. Paul, "Recent results and future challenges for large scale particleion- cell simulations of plasma-based accelerator concepts," Proc. of the SciDAC 2009 Conf., San Diego, CA, June, 2009 [Journal of Physics: Conference Series, vol. 180, Institute of Physics, Bristol and Philadelphia, 2009], p. 012005. [9] J.-L. Vay, C. M. Celata, M. A. Furman, G. Penn, M. Venturini, D. P. Grote, and K. G. Sonnad, ?Update on Electron-Cloud Simulations Using the Package WARP-POSINST.? Proc. of the 2009 Particle Accelerator Conference PAC09, Vancouver, Canada, June, 2009, paper FR5RFP078.« less

  12. Binary image encryption in a joint transform correlator scheme by aid of run-length encoding and QR code

    NASA Astrophysics Data System (ADS)

    Qin, Yi; Wang, Zhipeng; Wang, Hongjuan; Gong, Qiong

    2018-07-01

    We propose a binary image encryption method in joint transform correlator (JTC) by aid of the run-length encoding (RLE) and Quick Response (QR) code, which enables lossless retrieval of the primary image. The binary image is encoded with RLE to obtain the highly compressed data, and then the compressed binary image is further scrambled using a chaos-based method. The compressed and scrambled binary image is then transformed into one QR code that will be finally encrypted in JTC. The proposed method successfully, for the first time to our best knowledge, encodes a binary image into a QR code with the identical size of it, and therefore may probe a new way for extending the application of QR code in optical security. Moreover, the preprocessing operations, including RLE, chaos scrambling and the QR code translation, append an additional security level on JTC. We present digital results that confirm our approach.

  13. NeuCode Labeling in Nematodes: Proteomic and Phosphoproteomic Impact of Ascaroside Treatment in Caenorhabditis elegans*

    PubMed Central

    Rhoads, Timothy W.; Prasad, Aman; Kwiecien, Nicholas W.; Merrill, Anna E.; Zawack, Kelson; Westphall, Michael S.; Schroeder, Frank C.; Kimble, Judith; Coon, Joshua J.

    2015-01-01

    The nematode Caenorhabditis elegans is an important model organism for biomedical research. We previously described NeuCode stable isotope labeling by amino acids in cell culture (SILAC), a method for accurate proteome quantification with potential for multiplexing beyond the limits of traditional stable isotope labeling by amino acids in cell culture. Here we apply NeuCode SILAC to profile the proteomic and phosphoproteomic response of C. elegans to two potent members of the ascaroside family of nematode pheromones. By consuming labeled E. coli as part of their diet, C. elegans nematodes quickly and easily incorporate the NeuCode heavy lysine isotopologues by the young adult stage. Using this approach, we report, at high confidence, one of the largest proteomic and phosphoproteomic data sets to date in C. elegans: 6596 proteins at a false discovery rate ≤ 1% and 6620 phosphorylation isoforms with localization probability ≥75%. Our data reveal a post-translational signature of pheromone sensing that includes many conserved proteins implicated in longevity and response to stress. PMID:26392051

  14. Experimental QR code optical encryption: noise-free data recovering.

    PubMed

    Barrera, John Fredy; Mira-Agudelo, Alejandro; Torroba, Roberto

    2014-05-15

    We report, to our knowledge for the first time, the experimental implementation of a quick response (QR) code as a "container" in an optical encryption system. A joint transform correlator architecture in an interferometric configuration is chosen as the experimental scheme. As the implementation is not possible in a single step, a multiplexing procedure to encrypt the QR code of the original information is applied. Once the QR code is correctly decrypted, the speckle noise present in the recovered QR code is eliminated by a simple digital procedure. Finally, the original information is retrieved completely free of any kind of degradation after reading the QR code. Additionally, we propose and implement a new protocol in which the reception of the encrypted QR code and its decryption, the digital block processing, and the reading of the decrypted QR code are performed employing only one device (smartphone, tablet, or computer). The overall method probes to produce an outcome far more attractive to make the adoption of the technique a plausible option. Experimental results are presented to demonstrate the practicality of the proposed security system.

  15. Embedding QR codes in tumor board presentations, enhancing educational content for oncology information management.

    PubMed

    Siderits, Richard; Yates, Stacy; Rodriguez, Arelis; Lee, Tina; Rimmer, Cheryl; Roche, Mark

    2011-01-01

    Quick Response (QR) Codes are standard in supply management and seen with increasing frequency in advertisements. They are now present regularly in healthcare informatics and education. These 2-dimensional square bar codes, originally designed by the Toyota car company, are free of license and have a published international standard. The codes can be generated by free online software and the resulting images incorporated into presentations. The images can be scanned by "smart" phones and tablets using either the iOS or Android platforms, which link the device with the information represented by the QR code (uniform resource locator or URL, online video, text, v-calendar entries, short message service [SMS] and formatted text). Once linked to the device, the information can be viewed at any time after the original presentation, saved in the device or to a Web-based "cloud" repository, printed, or shared with others via email or Bluetooth file transfer. This paper describes how we use QR codes in our tumor board presentations, discusses the benefits, the different QR codes from Web links and how QR codes facilitate the distribution of educational content.

  16. Unraveling fabrication and calibration of wearable gas monitor for use under free-living conditions.

    PubMed

    Yue Deng; Cheng Chen; Tsow, Francis; Xiaojun Xian; Forzani, Erica

    2016-08-01

    Volatile organic compounds (VOC) are organic chemicals that have high vapor pressure at regular conditions. Some VOC could be dangerous to human health, therefore it is important to determine real-time indoor and outdoor personal exposures to VOC. To achieve this goal, our group has developed a wearable gas monitor with a complete sensor fabrication and calibration protocol for free-living conditions. Correction factors for calibrating the sensors, including sensitivity, aging effect, and temperature effect are implemented into a Quick Response Code (QR code), so that the pre-calibrated quartz tuning fork (QTF) sensor can be used with the wearable monitor under free-living conditions.

  17. Digital data for Quick Response (QR) codes of thermophiles to identify and compare the bacterial species isolated from Unkeshwar hot springs (India).

    PubMed

    Rekadwad, Bhagwan N; Khobragade, Chandrahasya N

    2016-03-01

    16S rRNA sequences of morphologically and biochemically identified 21 thermophilic bacteria isolated from Unkeshwar hot springs (19°85'N and 78°25'E), Dist. Nanded (India) has been deposited in NCBI repository. The 16S rRNA gene sequences were used to generate QR codes for sequences (FASTA format and full Gene Bank information). Diversity among the isolates is compared with known isolates and evaluated using CGR, FCGR and PCA i.e. visual comparison and evaluation respectively. Considerable biodiversity was observed among the identified bacteria isolated from Unkeshwar hot springs. The hyperlinked QR codes, CGR, FCGR and PCA of all the isolates are made available to the users on a portal https://sites.google.com/site/bhagwanrekadwad/.

  18. A Computational Model for Predicting Gas Breakdown

    NASA Astrophysics Data System (ADS)

    Gill, Zachary

    2017-10-01

    Pulsed-inductive discharges are a common method of producing a plasma. They provide a mechanism for quickly and efficiently generating a large volume of plasma for rapid use and are seen in applications including propulsion, fusion power, and high-power lasers. However, some common designs see a delayed response time due to the plasma forming when the magnitude of the magnetic field in the thruster is at a minimum. New designs are difficult to evaluate due to the amount of time needed to construct a new geometry and the high monetary cost of changing the power generation circuit. To more quickly evaluate new designs and better understand the shortcomings of existing designs, a computational model is developed. This model uses a modified single-electron model as the basis for a Mathematica code to determine how the energy distribution in a system changes with regards to time and location. By analyzing this energy distribution, the approximate time and location of initial plasma breakdown can be predicted. The results from this code are then compared to existing data to show its validity and shortcomings. Missouri S&T APLab.

  19. Automatic generation of user material subroutines for biomechanical growth analysis.

    PubMed

    Young, Jonathan M; Yao, Jiang; Ramasubramanian, Ashok; Taber, Larry A; Perucchio, Renato

    2010-10-01

    The analysis of the biomechanics of growth and remodeling in soft tissues requires the formulation of specialized pseudoelastic constitutive relations. The nonlinear finite element analysis package ABAQUS allows the user to implement such specialized material responses through the coding of a user material subroutine called UMAT. However, hand coding UMAT subroutines is a challenge even for simple pseudoelastic materials and requires substantial time to debug and test the code. To resolve this issue, we develop an automatic UMAT code generation procedure for pseudoelastic materials using the symbolic mathematics package MATHEMATICA and extend the UMAT generator to include continuum growth. The performance of the automatically coded UMAT is tested by simulating the stress-stretch response of a material defined by a Fung-orthotropic strain energy function, subject to uniaxial stretching, equibiaxial stretching, and simple shear in ABAQUS. The MATHEMATICA UMAT generator is then extended to include continuum growth by adding a growth subroutine to the automatically generated UMAT. The MATHEMATICA UMAT generator correctly derives the variables required in the UMAT code, quickly providing a ready-to-use UMAT. In turn, the UMAT accurately simulates the pseudoelastic response. In order to test the growth UMAT, we simulate the growth-based bending of a bilayered bar with differing fiber directions in a nongrowing passive layer. The anisotropic passive layer, being topologically tied to the growing isotropic layer, causes the bending bar to twist laterally. The results of simulations demonstrate the validity of the automatically coded UMAT, used in both standardized tests of hyperelastic materials and for a biomechanical growth analysis.

  20. Integration of QR codes into an anesthesia information management system for resident case log management.

    PubMed

    Avidan, Alexander; Weissman, Charles; Levin, Phillip D

    2015-04-01

    Quick response (QR) codes containing anesthesia syllabus data were introduced into an anesthesia information management system. The code was generated automatically at the conclusion of each case and available for resident case logging using a smartphone or tablet. The goal of this study was to evaluate the use and usability/user-friendliness of such system. Resident case logging practices were assessed prior to introducing the QR codes. QR code use and satisfactions amongst residents was reassessed at three and six months. Before QR code introduction only 12/23 (52.2%) residents maintained a case log. Most of the remaining residents (9/23, 39.1%) expected to receive a case list from the anesthesia information management system database at the end of their residency. At three months and six months 17/26 (65.4%) and 15/25 (60.0%) residents, respectively, were using the QR codes. Satisfaction was rated as very good or good. QR codes for residents' case logging with smartphones or tablets were successfully introduced in an anesthesia information management system and used by most residents. QR codes can be successfully implemented into medical practice to support data transfer. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  1. Vector radiative transfer code SORD: Performance analysis and quick start guide

    NASA Astrophysics Data System (ADS)

    Korkin, Sergey; Lyapustin, Alexei; Sinyuk, Alexander; Holben, Brent; Kokhanovsky, Alexander

    2017-10-01

    We present a new open source polarized radiative transfer code SORD written in Fortran 90/95. SORD numerically simulates propagation of monochromatic solar radiation in a plane-parallel atmosphere over a reflecting surface using the method of successive orders of scattering (hence the name). Thermal emission is ignored. We did not improve the method in any way, but report the accuracy and runtime in 52 benchmark scenarios. This paper also serves as a quick start user's guide for the code available from ftp://maiac.gsfc.nasa.gov/pub/skorkin, from the JQSRT website, or from the corresponding (first) author.

  2. DoOR 2.0 - Comprehensive Mapping of Drosophila melanogaster Odorant Responses

    NASA Astrophysics Data System (ADS)

    Münch, Daniel; Galizia, C. Giovanni

    2016-02-01

    Odors elicit complex patterns of activated olfactory sensory neurons. Knowing the complete olfactome, i.e. the responses in all sensory neurons for all relevant odorants, is desirable to understand olfactory coding. The DoOR project combines all available Drosophila odorant response data into a single consensus response matrix. Since its first release many studies were published: receptors were deorphanized and several response profiles were expanded. In this study, we add unpublished data to the odor-response profiles for four odorant receptors (Or10a, Or42b, Or47b, Or56a). We deorphanize Or69a, showing a broad response spectrum with the best ligands including 3-hydroxyhexanoate, alpha-terpineol, 3-octanol and linalool. We include all of these datasets into DoOR, provide a comprehensive update of both code and data, and new tools for data analyses and visualizations. The DoOR project has a web interface for quick queries (http://neuro.uni.kn/DoOR), and a downloadable, open source toolbox written in R, including all processed and original datasets. DoOR now gives reliable odorant-responses for nearly all Drosophila olfactory responding units, listing 693 odorants, for a total of 7381 data points.

  3. Digital data for Quick Response (QR) codes of thermophiles to identify and compare the bacterial species isolated from Unkeshwar hot springs (India)

    PubMed Central

    Rekadwad, Bhagwan N.; Khobragade, Chandrahasya N.

    2015-01-01

    16S rRNA sequences of morphologically and biochemically identified 21 thermophilic bacteria isolated from Unkeshwar hot springs (19°85′N and 78°25′E), Dist. Nanded (India) has been deposited in NCBI repository. The 16S rRNA gene sequences were used to generate QR codes for sequences (FASTA format and full Gene Bank information). Diversity among the isolates is compared with known isolates and evaluated using CGR, FCGR and PCA i.e. visual comparison and evaluation respectively. Considerable biodiversity was observed among the identified bacteria isolated from Unkeshwar hot springs. The hyperlinked QR codes, CGR, FCGR and PCA of all the isolates are made available to the users on a portal https://sites.google.com/site/bhagwanrekadwad/. PMID:26793757

  4. Designing for Compressive Sensing: Compressive Art, Camouflage, Fonts, and Quick Response Codes

    DTIC Science & Technology

    2018-01-01

    an example where the signal is non-sparse in the standard basis, but sparse in the discrete cosine basis . The top plot shows the signal from the...previous example, now used as sparse discrete cosine transform (DCT) coefficients . The next plot shows the non-sparse signal in the standard...Romberg JK, Tao T. Stable signal recovery from incomplete and inaccurate measurements. Commun Pure Appl Math . 2006;59(8):1207–1223. 3. Donoho DL

  5. The Umbra Simulation and Integration Framework Applied to Emergency Response Training

    NASA Technical Reports Server (NTRS)

    Hamilton, Paul Lawrence; Britain, Robert

    2010-01-01

    The Mine Emergency Response Interactive Training Simulation (MERITS) is intended to prepare personnel to manage an emergency in an underground coal mine. The creation of an effective training environment required realistic emergent behavior in response to simulation events and trainee interventions, exploratory modification of miner behavior rules, realistic physics, and incorporation of legacy code. It also required the ability to add rich media to the simulation without conflicting with normal desktop security settings. Our Umbra Simulation and Integration Framework facilitated agent-based modeling of miners and rescuers and made it possible to work with subject matter experts to quickly adjust behavior through script editing, rather than through lengthy programming and recompilation. Integration of Umbra code with the WebKit browser engine allowed the use of JavaScript-enabled local web pages for media support. This project greatly extended the capabilities of Umbra in support of training simulations and has implications for simulations that combine human behavior, physics, and rich media.

  6. Enhanced quasi-static particle-in-cell simulation of electron cloud instabilities in circular accelerators

    NASA Astrophysics Data System (ADS)

    Feng, Bing

    Electron cloud instabilities have been observed in many circular accelerators around the world and raised concerns of future accelerators and possible upgrades. In this thesis, the electron cloud instabilities are studied with the quasi-static particle-in-cell (PIC) code QuickPIC. Modeling in three-dimensions the long timescale propagation of beam in electron clouds in circular accelerators requires faster and more efficient simulation codes. Thousands of processors are easily available for parallel computations. However, it is not straightforward to increase the effective speed of the simulation by running the same problem size on an increasingly number of processors because there is a limit to domain size in the decomposition of the two-dimensional part of the code. A pipelining algorithm applied on the fully parallelized particle-in-cell code QuickPIC is implemented to overcome this limit. The pipelining algorithm uses multiple groups of processors and optimizes the job allocation on the processors in parallel computing. With this novel algorithm, it is possible to use on the order of 102 processors, and to expand the scale and the speed of the simulation with QuickPIC by a similar factor. In addition to the efficiency improvement with the pipelining algorithm, the fidelity of QuickPIC is enhanced by adding two physics models, the beam space charge effect and the dispersion effect. Simulation of two specific circular machines is performed with the enhanced QuickPIC. First, the proposed upgrade to the Fermilab Main Injector is studied with an eye upon guiding the design of the upgrade and code validation. Moderate emittance growth is observed for the upgrade of increasing the bunch population by 5 times. But the simulation also shows that increasing the beam energy from 8GeV to 20GeV or above can effectively limit the emittance growth. Then the enhanced QuickPIC is used to simulate the electron cloud effect on electron beam in the Cornell Energy Recovery Linac (ERL) due to extremely small emittance and high peak currents anticipated in the machine. A tune shift is discovered from the simulation; however, emittance growth of the electron beam in electron cloud is not observed for ERL parameters.

  7. Development of Northeast Asia Nuclear Power Plant Accident Simulator.

    PubMed

    Kim, Juyub; Kim, Juyoul; Po, Li-Chi Cliff

    2017-06-15

    A conclusion from the lessons learned after the March 2011 Fukushima Daiichi accident was that Korea needs a tool to estimate consequences from a major accident that could occur at a nuclear power plant located in a neighboring country. This paper describes a suite of computer-based codes to be used by Korea's nuclear emergency response staff for training and potentially operational support in Korea's national emergency preparedness and response program. The systems of codes, Northeast Asia Nuclear Accident Simulator (NANAS), consist of three modules: source-term estimation, atmospheric dispersion prediction and dose assessment. To quickly assess potential doses to the public in Korea, NANAS includes specific reactor data from the nuclear power plants in China, Japan and Taiwan. The completed simulator is demonstrated using data for a hypothetical release. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  8. UV-responsive polyvinyl alcohol nanofibers prepared by electrospinning

    NASA Astrophysics Data System (ADS)

    Khatri, Zeeshan; Ali, Shamshad; Khatri, Imran; Mayakrishnan, Gopiraman; Kim, Seong Hun; Kim, Ick-Soo

    2015-07-01

    We report UV-responsive polyvinyl alcohol (PVA) nanofibers for potential application for recording and erasing quick response (QR) codes. We incorporate 1‧-3‧-dihydro-8-methoxy-1‧,3‧,3‧-trimethyl-6-nitrospiro [2H-1-benzopyran-2,2‧-(2H)-indole] (indole) and,3-dihydro-1,3,3-trimethylspiro [2H-indole-2,3‧-[3H] phenanthr [9,10-b] (1,4) oxazine] (oxazine) into PVA polymer matrix via electrospinning technique. The resultant nanofibers were measured for recording-erasing, photo-coloration and thermal reversibility. The rate of photo-coloration of PVA-indole nanofibers was five times higher than the PVA-oxazine nanofibers, whereas the thermal reversibility found to be more than twice as fast as PVA-oxazine nanofibers. Results showed that the resultant nanofibers have very good capability of recording QR codes multiple times. The FTIR spectroscopy and SEM were employed to characterize the electrospun nanofibers. The UV-responsive PVA nanofibers have great potentials as a light-driven nanomaterials incorporated within sensors, sensitive displays and in optical devices such as erasable and rewritable optical storage.

  9. Successful Therapist-Parent Coaching: How In Vivo Feedback Relates to Parent Engagement in Parent-Child Interaction Therapy.

    PubMed

    Barnett, Miya L; Niec, Larissa N; Peer, Samuel O; Jent, Jason F; Weinstein, Allison; Gisbert, Patricia; Simpson, Gregory

    2017-01-01

    Although behavioral parent training is considered efficacious treatment for childhood conduct problems, not all families benefit equally from treatment. Some parents take longer to change their behaviors and others ultimately drop out. Understanding how therapist behaviors impact parental engagement is necessary to improve treatment utilization. This study investigated how different techniques of therapist in vivo feedback (i.e., coaching) influenced parent attrition and skill acquisition in parent-child interaction therapy (PCIT). Participants included 51 parent-child dyads who participated in PCIT. Children (age: M = 5.03, SD = 1.65) were predominately minorities (63% White Hispanic, 16% African American or Black). Eight families discontinued treatment prematurely. Therapist coaching techniques during the first session of treatment were coded using the Therapist-Parent Interaction Coding System, and parent behaviors were coded with the Dyadic Parent-Child Interaction Coding System, Third Edition. Parents who received more responsive coaching acquired child-centered parenting skills more quickly. Therapists used fewer responsive techniques and more drills with families who dropped out of treatment. A composite of therapist behaviors accurately predicted treatment completion for 86% of families. Although group membership was correctly classified for the treatment completers, only 1 dropout was accurately predicted. Findings suggest that therapist in vivo feedback techniques may impact parents' success in PCIT and that responsive coaching may be particularly relevant.

  10. Interactive Software For Astrodynamical Calculations

    NASA Technical Reports Server (NTRS)

    Schlaifer, Ronald S.; Skinner, David L.; Roberts, Phillip H.

    1995-01-01

    QUICK computer program provides user with facilities of sophisticated desk calculator performing scalar, vector, and matrix arithmetic; propagate conic-section orbits; determines planetary and satellite coordinates; and performs other related astrodynamic calculations within FORTRAN-like software environment. QUICK is interpreter, and no need to use compiler or linker to run QUICK code. Outputs plotted in variety of formats on variety of terminals. Written in RATFOR.

  11. The EPQ Code System for Simulating the Thermal Response of Plasma-Facing Components to High-Energy Electron Impact

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ward, Robert Cameron; Steiner, Don

    2004-06-15

    The generation of runaway electrons during a thermal plasma disruption is a concern for the safe and economical operation of a tokamak power system. Runaway electrons have high energy, 10 to 300 MeV, and may potentially cause extensive damage to plasma-facing components (PFCs) through large temperature increases, melting of metallic components, surface erosion, and possible burnout of coolant tubes. The EPQ code system was developed to simulate the thermal response of PFCs to a runaway electron impact. The EPQ code system consists of several parts: UNIX scripts that control the operation of an electron-photon Monte Carlo code to calculate themore » interaction of the runaway electrons with the plasma-facing materials; a finite difference code to calculate the thermal response, melting, and surface erosion of the materials; a code to process, scale, transform, and convert the electron Monte Carlo data to volumetric heating rates for use in the thermal code; and several minor and auxiliary codes for the manipulation and postprocessing of the data. The electron-photon Monte Carlo code used was Electron-Gamma-Shower (EGS), developed and maintained by the National Research Center of Canada. The Quick-Therm-Two-Dimensional-Nonlinear (QTTN) thermal code solves the two-dimensional cylindrical modified heat conduction equation using the Quickest third-order accurate and stable explicit finite difference method and is capable of tracking melting or surface erosion. The EPQ code system is validated using a series of analytical solutions and simulations of experiments. The verification of the QTTN thermal code with analytical solutions shows that the code with the Quickest method is better than 99.9% accurate. The benchmarking of the EPQ code system and QTTN versus experiments showed that QTTN's erosion tracking method is accurate within 30% and that EPQ is able to predict the occurrence of melting within the proper time constraints. QTTN and EPQ are verified and validated as able to calculate the temperature distribution, phase change, and surface erosion successfully.« less

  12. Consumer acceptance of a quick response (QR) code for the food traceability system: Application of an extended technology acceptance model (TAM).

    PubMed

    Kim, Yeong Gug; Woo, Eunju

    2016-07-01

    The objectives of this study are to apply the TAM using the addition of perceived information to individuals' behavioral intention to use the QR code for the food traceability system; and to determine the moderating effects of food involvement on the relationship between perceived information and perceived usefulness. Results from a survey of 420 respondents are analyzed using structural equation modeling. The study findings reveal that the extended TAM has a satisfactory fit to the data and that the underlying dimensions have a significant effect on consumers' intention to use the QR code for the food traceability system. In addition, food involvement plays a significant moderating function in the relationship between perceived information and perceived usefulness. The implications of this study for future research are discussed. Copyright © 2016 Elsevier Ltd. All rights reserved.

  13. An Ontology-Based, Mobile-Optimized System for Pharmacogenomic Decision Support at the Point-of-Care

    PubMed Central

    Miñarro-Giménez, Jose Antonio; Blagec, Kathrin; Boyce, Richard D.; Adlassnig, Klaus-Peter; Samwald, Matthias

    2014-01-01

    Background The development of genotyping and genetic sequencing techniques and their evolution towards low costs and quick turnaround have encouraged a wide range of applications. One of the most promising applications is pharmacogenomics, where genetic profiles are used to predict the most suitable drugs and drug dosages for the individual patient. This approach aims to ensure appropriate medical treatment and avoid, or properly manage, undesired side effects. Results We developed the Medicine Safety Code (MSC) service, a novel pharmacogenomics decision support system, to provide physicians and patients with the ability to represent pharmacogenomic data in computable form and to provide pharmacogenomic guidance at the point-of-care. Pharmacogenomic data of individual patients are encoded as Quick Response (QR) codes and can be decoded and interpreted with common mobile devices without requiring a centralized repository for storing genetic patient data. In this paper, we present the first fully functional release of this system and describe its architecture, which utilizes Web Ontology Language 2 (OWL 2) ontologies to formalize pharmacogenomic knowledge and to provide clinical decision support functionalities. Conclusions The MSC system provides a novel approach for enabling the implementation of personalized medicine in clinical routine. PMID:24787444

  14. An ontology-based, mobile-optimized system for pharmacogenomic decision support at the point-of-care.

    PubMed

    Miñarro-Giménez, Jose Antonio; Blagec, Kathrin; Boyce, Richard D; Adlassnig, Klaus-Peter; Samwald, Matthias

    2014-01-01

    The development of genotyping and genetic sequencing techniques and their evolution towards low costs and quick turnaround have encouraged a wide range of applications. One of the most promising applications is pharmacogenomics, where genetic profiles are used to predict the most suitable drugs and drug dosages for the individual patient. This approach aims to ensure appropriate medical treatment and avoid, or properly manage, undesired side effects. We developed the Medicine Safety Code (MSC) service, a novel pharmacogenomics decision support system, to provide physicians and patients with the ability to represent pharmacogenomic data in computable form and to provide pharmacogenomic guidance at the point-of-care. Pharmacogenomic data of individual patients are encoded as Quick Response (QR) codes and can be decoded and interpreted with common mobile devices without requiring a centralized repository for storing genetic patient data. In this paper, we present the first fully functional release of this system and describe its architecture, which utilizes Web Ontology Language 2 (OWL 2) ontologies to formalize pharmacogenomic knowledge and to provide clinical decision support functionalities. The MSC system provides a novel approach for enabling the implementation of personalized medicine in clinical routine.

  15. High-throughput fabrication of anti-counterfeiting colloid-based photoluminescent microtags using electrical nanoimprint lithography

    NASA Astrophysics Data System (ADS)

    Diaz, R.; Palleau, E.; Poirot, D.; Sangeetha, N. M.; Ressier, L.

    2014-08-01

    This work demonstrates the excellent capability of the recently developed electrical nanoimprint lithography (e-NIL) technique for quick, high-throughput production of well-defined colloid assemblies on surfaces. This is shown by fabricating micron-sized photoluminescent quick response (QR) codes based on the electrostatic directed trapping (so called nanoxerography process) of 28 nm colloidal lanthanide-doped upconverting NaYF4 nanocrystals. Influencing experimental parameters have been optimized and the contribution of triboelectrification in e-NIL was evidenced. Under the chosen conditions, more than 300 000 nanocrystal-based QR codes were fabricated on a 4 inch silicon wafer, in less than 15 min. These microtags were then transferred to transparent flexible films, to be easily integrated onto desired products. Invisible to the naked eye, they can be decoded and authenticated using an optical microscopy image of their specific photoluminescence mapping. Beyond this very promising application for product tracking and the anti-counterfeiting strategies, e-NIL nanoxerography, potentially applicable to any types of charged and/or polarizable colloids and pattern geometries opens up tremendous opportunities for industrial scale production of various other kinds of colloid-based devices and sensors.

  16. Farm Mapping to Assist, Protect, and Prepare Emergency Responders: Farm MAPPER.

    PubMed

    Reyes, Iris; Rollins, Tami; Mahnke, Andrea; Kadolph, Christopher; Minor, Gerald; Keifer, Matthew

    2014-01-01

    Responders such as firefighters and emergency medical technicians who respond to farm emergencies often face complex and unknown environments. They may encounter hazards such as fuels, solvents, pesticides, caustics, and exploding gas storage cylinders. Responders may be unaware of dirt roads within the farm that can expedite their arrival at critical sites or snow-covered manure pits that act as hidden hazards. A response to a farm, unless guided by someone familiar with the operation, may present a risk to responders and post a challenge in locating the victim. This project explored the use of a Web-based farm-mapping application optimized for tablets and accessible via easily accessible on-site matrix barcodes, or quick response codes (QR codes), to provide emergency responders with hazard and resource information to agricultural operations. Secured portals were developed for both farmers and responders, allowing both parties to populate and customize farm maps with icons. Data were stored online and linked to QR codes attached to mailbox posts where emergency responders may read them with a mobile device. Mock responses were conducted on dairy farms to test QR code linking efficacy, Web site security, and field usability. Findings from farmer usability tests showed willingness to enter data as well as ease of Web site navigation and data entry even with farmers who had limited computer knowledge. Usability tests with emergency responders showed ease of QR code connectivity to the farm maps and ease of Web site navigation. Further research is needed to improve data security as well as assess the program's applicability to nonfarm environments and integration with existing emergency response systems. The next phases of this project will expand the program for regional and national use, develop QR code-linked, Web-based extrication guidance for farm machinery for victim entrapment rescue, and create QR code-linked online training videos and materials for limited English proficient immigrant farm workers.

  17. QR code optical encryption using spatially incoherent illumination

    NASA Astrophysics Data System (ADS)

    Cheremkhin, P. A.; Krasnov, V. V.; Rodin, V. G.; Starikov, R. S.

    2017-02-01

    Optical encryption is an actively developing field of science. The majority of encryption techniques use coherent illumination and suffer from speckle noise, which severely limits their applicability. The spatially incoherent encryption technique does not have this drawback, but its effectiveness is dependent on the Fourier spectrum properties of the image to be encrypted. The application of a quick response (QR) code in the capacity of a data container solves this problem, and the embedded error correction code also enables errorless decryption. The optical encryption of digital information in the form of QR codes using spatially incoherent illumination was implemented experimentally. The encryption is based on the optical convolution of the image to be encrypted with the kinoform point spread function, which serves as an encryption key. Two liquid crystal spatial light modulators were used in the experimental setup for the QR code and the kinoform imaging, respectively. The quality of the encryption and decryption was analyzed in relation to the QR code size. Decryption was conducted digitally. The successful decryption of encrypted QR codes of up to 129  ×  129 pixels was demonstrated. A comparison with the coherent QR code encryption technique showed that the proposed technique has a signal-to-noise ratio that is at least two times higher.

  18. Stroke Severity Affects Timing: Time From Stroke Code Activation to Initial Imaging is Longer in Patients With Milder Strokes.

    PubMed

    Kwei, Kimberly T; Liang, John; Wilson, Natalie; Tuhrim, Stanley; Dhamoon, Mandip

    2018-05-01

    Optimizing the time it takes to get a potential stroke patient to imaging is essential in a rapid stroke response. At our hospital, door-to-imaging time is comprised of 2 time periods: the time before a stroke is recognized, followed by the period after the stroke code is called during which the stroke team assesses and brings the patient to the computed tomography scanner. To control for delays due to triage, we isolated the time period after a potential stroke has been recognized, as few studies have examined the biases of stroke code responders. This "code-to-imaging time" (CIT) encompassed the time from stroke code activation to initial imaging, and we hypothesized that perception of stroke severity would affect how quickly stroke code responders act. In consecutively admitted ischemic stroke patients at The Mount Sinai Hospital emergency department, we tested associations between National Institutes of Health Stroke Scale scores (NIHSS), continuously and at different cutoffs, and CIT using spline regression, t tests for univariate analysis, and multivariable linear regression adjusting for age, sex, and race/ethnicity. In our study population, mean CIT was 26 minutes, and mean presentation NIHSS was 8. In univariate and multivariate analyses comparing CIT between mild and severe strokes, stroke scale scores <4 were associated with longer response times. Milder strokes are associated with a longer CIT with a threshold effect at a NIHSS of 4.

  19. Durability of switchable QR code carriers under hydrolytic and photolytic conditions

    NASA Astrophysics Data System (ADS)

    Ecker, Melanie; Pretsch, Thorsten

    2013-09-01

    Following a guest diffusion approach, the surface of a shape memory poly(ester urethane) (PEU) was either black or blue colored. Bowtie-shaped quick response (QR) code carriers were then obtained from laser engraving and cutting, before thermo-mechanical functionalization (programming) was applied to stabilize the PEU in a thermo-responsive (switchable) state. The stability of the dye within the polymer surface and long-term functionality of the polymer were investigated against UVA and hydrolytic ageing. Spectrophotometric investigations verified UVA ageing-related color shifts from black to yellow-brownish and blue to petrol-greenish whereas hydrolytically aged samples changed from black to greenish and blue to light blue. In the case of UVA ageing, color changes were accompanied by dye decolorization, whereas hydrolytic ageing led to contrast declines due to dye diffusion. The Michelson contrast could be identified as an effective tool to follow ageing-related contrast changes between surface-dyed and laser-ablated (undyed) polymer regions. As soon as the Michelson contrast fell below a crucial value of 0.1 due to ageing, the QR code was no longer decipherable with a scanning device. Remarkably, the PEU information carrier base material could even then be adequately fixed and recovered. Hence, the surface contrast turned out to be the decisive parameter for QR code carrier applicability.

  20. DNA barcode goes two-dimensions: DNA QR code web server.

    PubMed

    Liu, Chang; Shi, Linchun; Xu, Xiaolan; Li, Huan; Xing, Hang; Liang, Dong; Jiang, Kun; Pang, Xiaohui; Song, Jingyuan; Chen, Shilin

    2012-01-01

    The DNA barcoding technology uses a standard region of DNA sequence for species identification and discovery. At present, "DNA barcode" actually refers to DNA sequences, which are not amenable to information storage, recognition, and retrieval. Our aim is to identify the best symbology that can represent DNA barcode sequences in practical applications. A comprehensive set of sequences for five DNA barcode markers ITS2, rbcL, matK, psbA-trnH, and CO1 was used as the test data. Fifty-three different types of one-dimensional and ten two-dimensional barcode symbologies were compared based on different criteria, such as coding capacity, compression efficiency, and error detection ability. The quick response (QR) code was found to have the largest coding capacity and relatively high compression ratio. To facilitate the further usage of QR code-based DNA barcodes, a web server was developed and is accessible at http://qrfordna.dnsalias.org. The web server allows users to retrieve the QR code for a species of interests, convert a DNA sequence to and from a QR code, and perform species identification based on local and global sequence similarities. In summary, the first comprehensive evaluation of various barcode symbologies has been carried out. The QR code has been found to be the most appropriate symbology for DNA barcode sequences. A web server has also been constructed to allow biologists to utilize QR codes in practical DNA barcoding applications.

  1. Web Application to Monitor Logistics Distribution of Disaster Relief Using the CodeIgniter Framework

    NASA Astrophysics Data System (ADS)

    Jamil, Mohamad; Ridwan Lessy, Mohamad

    2018-03-01

    Disaster management is the responsibility of the central government and local governments. The principles of disaster management, among others, are quick and precise, priorities, coordination and cohesion, efficient and effective manner. Help that is needed by most societies are logistical assistance, such as the assistance covers people’s everyday needs, such as food, instant noodles, fast food, blankets, mattresses etc. Logistical assistance is needed for disaster management, especially in times of disasters. The support of logistical assistance must be timely, to the right location, target, quality, quantity, and needs. The purpose of this study is to make a web application to monitorlogistics distribution of disaster relefusing CodeIgniter framework. Through this application, the mechanisms of aid delivery will be easily controlled from and heading to the disaster site.

  2. LncRNApred: Classification of Long Non-Coding RNAs and Protein-Coding Transcripts by the Ensemble Algorithm with a New Hybrid Feature.

    PubMed

    Pian, Cong; Zhang, Guangle; Chen, Zhi; Chen, Yuanyuan; Zhang, Jin; Yang, Tao; Zhang, Liangyun

    2016-01-01

    As a novel class of noncoding RNAs, long noncoding RNAs (lncRNAs) have been verified to be associated with various diseases. As large scale transcripts are generated every year, it is significant to accurately and quickly identify lncRNAs from thousands of assembled transcripts. To accurately discover new lncRNAs, we develop a classification tool of random forest (RF) named LncRNApred based on a new hybrid feature. This hybrid feature set includes three new proposed features, which are MaxORF, RMaxORF and SNR. LncRNApred is effective for classifying lncRNAs and protein coding transcripts accurately and quickly. Moreover,our RF model only requests the training using data on human coding and non-coding transcripts. Other species can also be predicted by using LncRNApred. The result shows that our method is more effective compared with the Coding Potential Calculate (CPC). The web server of LncRNApred is available for free at http://mm20132014.wicp.net:57203/LncRNApred/home.jsp.

  3. Code Parallelization with CAPO: A User Manual

    NASA Technical Reports Server (NTRS)

    Jin, Hao-Qiang; Frumkin, Michael; Yan, Jerry; Biegel, Bryan (Technical Monitor)

    2001-01-01

    A software tool has been developed to assist the parallelization of scientific codes. This tool, CAPO, extends an existing parallelization toolkit, CAPTools developed at the University of Greenwich, to generate OpenMP parallel codes for shared memory architectures. This is an interactive toolkit to transform a serial Fortran application code to an equivalent parallel version of the software - in a small fraction of the time normally required for a manual parallelization. We first discuss the way in which loop types are categorized and how efficient OpenMP directives can be defined and inserted into the existing code using the in-depth interprocedural analysis. The use of the toolkit on a number of application codes ranging from benchmark to real-world application codes is presented. This will demonstrate the great potential of using the toolkit to quickly parallelize serial programs as well as the good performance achievable on a large number of toolkit to quickly parallelize serial programs as well as the good performance achievable on a large number of processors. The second part of the document gives references to the parameters and the graphic user interface implemented in the toolkit. Finally a set of tutorials is included for hands-on experiences with this toolkit.

  4. Towards an Integrated QR Code Biosensor: Light-Driven Sample Acquisition and Bacterial Cellulose Paper Substrate.

    PubMed

    Yuan, Mingquan; Jiang, Qisheng; Liu, Keng-Ku; Singamaneni, Srikanth; Chakrabartty, Shantanu

    2018-06-01

    This paper addresses two key challenges toward an integrated forward error-correcting biosensor based on our previously reported self-assembled quick-response (QR) code. The first challenge involves the choice of the paper substrate for printing and self-assembling the QR code. We have compared four different substrates that includes regular printing paper, Whatman filter paper, nitrocellulose membrane and lab synthesized bacterial cellulose. We report that out of the four substrates bacterial cellulose outperforms the others in terms of probe (gold nanorods) and ink retention capability. The second challenge involves remote activation of the analyte sampling and the QR code self-assembly process. In this paper, we use light as a trigger signal and a graphite layer as a light-absorbing material. The resulting change in temperature due to infrared absorption leads to a temperature gradient that then exerts a diffusive force driving the analyte toward the regions of self-assembly. The working principle has been verified in this paper using assembled biosensor prototypes where we demonstrate higher sample flow rate due to light induced thermal gradients.

  5. A review of automatic patient identification options for public health care centers with restricted budgets.

    PubMed

    García-Betances, Rebeca I; Huerta, Mónica K

    2012-01-01

    A comparative review is presented of available technologies suitable for automatic reading of patient identification bracelet tags. Existing technologies' backgrounds, characteristics, advantages and disadvantages, are described in relation to their possible use by public health care centers with budgetary limitations. A comparative assessment is presented of suitable automatic identification systems based on graphic codes, both one- (1D) and two-dimensional (2D), printed on labels, as well as those based on radio frequency identification (RFID) tags. The analysis looks at the tradeoffs of these technologies to provide guidance to hospital administrator looking to deploy patient identification technology. The results suggest that affordable automatic patient identification systems can be easily and inexpensively implemented using 2D code printed on low cost bracelet labels, which can then be read and automatically decoded by ordinary mobile smart phones. Because of mobile smart phones' present versatility and ubiquity, the implantation and operation of 2D code, and especially Quick Response® (QR) Code, technology emerges as a very attractive alternative to automate the patients' identification processes in low-budget situations.

  6. A Review of Automatic Patient Identification Options for Public Health Care Centers with Restricted Budgets

    PubMed Central

    García-Betances, Rebeca I.; Huerta, Mónica K.

    2012-01-01

    A comparative review is presented of available technologies suitable for automatic reading of patient identification bracelet tags. Existing technologies’ backgrounds, characteristics, advantages and disadvantages, are described in relation to their possible use by public health care centers with budgetary limitations. A comparative assessment is presented of suitable automatic identification systems based on graphic codes, both one- (1D) and two-dimensional (2D), printed on labels, as well as those based on radio frequency identification (RFID) tags. The analysis looks at the tradeoffs of these technologies to provide guidance to hospital administrator looking to deploy patient identification technology. The results suggest that affordable automatic patient identification systems can be easily and inexpensively implemented using 2D code printed on low cost bracelet labels, which can then be read and automatically decoded by ordinary mobile smart phones. Because of mobile smart phones’ present versatility and ubiquity, the implantation and operation of 2D code, and especially Quick Response® (QR) Code, technology emerges as a very attractive alternative to automate the patients’ identification processes in low-budget situations. PMID:23569629

  7. Advanced simulation of mixed-material erosion/evolution and application to low and high-Z containing plasma facing components

    NASA Astrophysics Data System (ADS)

    Brooks, J. N.; Hassanein, A.; Sizyuk, T.

    2013-07-01

    Plasma interactions with mixed-material surfaces are being analyzed using advanced modeling of time-dependent surface evolution/erosion. Simulations use the REDEP/WBC erosion/redeposition code package coupled to the HEIGHTS package ITMC-DYN mixed-material formation/response code, with plasma parameter input from codes and data. We report here on analysis for a DIII-D Mo/C containing tokamak divertor. A DIII-D/DiMES probe experiment simulation predicts that sputtered molybdenum from a 1 cm diameter central spot quickly saturates (˜4 s) in the 5 cm diameter surrounding carbon probe surface, with subsequent re-sputtering and transport to off-probe divertor regions, and with high (˜50%) redeposition on the Mo spot. Predicted Mo content in the carbon agrees well with post-exposure probe data. We discuss implications and mixed-material analysis issues for Be/W mixing at the ITER outer divertor, and Li, C, Mo mixing at an NSTX divertor.

  8. Customized data container for improved performance in optical cryptosystems

    NASA Astrophysics Data System (ADS)

    Vélez Zea, Alejandro; Fredy Barrera, John; Torroba, Roberto

    2016-12-01

    Coherent optical encryption procedures introduce speckle noise to the output, limiting many practical applications. Until now the only method available to avoid this noise is to codify the information to be processed into a container that is encrypted instead of the original data. Although the decrypted container presents the noise due to the optical processing, their features remain recognizable enough to allow decoding, bringing the original information free of any kind of degradation. The first adopted containers were the quick response (QR) codes. However, the limitations of optical encryption procedures and the features of QR codes imply that in practice only simple codes containing small amounts of data can be processed without large experimental requirements. In order to overcome this problem, we introduce the first tailor made container to be processed in optical cryptosystems, ensuring larger noise tolerance and the ability to process more information with less experimental requirements. We present both simulations and experimental results to demonstrate the advantages of our proposal.

  9. Three-dimensional polarization marked multiple-QR code encryption by optimizing a single vectorial beam

    NASA Astrophysics Data System (ADS)

    Lin, Chao; Shen, Xueju; Hua, Binbin; Wang, Zhisong

    2015-10-01

    We demonstrate the feasibility of three dimensional (3D) polarization multiplexing by optimizing a single vectorial beam using a multiple-signal window multiple-plane (MSW-MP) phase retrieval algorithm. Original messages represented with multiple quick response (QR) codes are first partitioned into a series of subblocks. Then, each subblock is marked with a specific polarization state and randomly distributed in 3D space with both longitudinal and transversal adjustable freedoms. A generalized 3D polarization mapping protocol is established to generate a 3D polarization key. Finally, multiple-QR code is encrypted into one phase only mask and one polarization only mask based on the modified Gerchberg-Saxton (GS) algorithm. We take the polarization mask as the cyphertext and the phase only mask as additional dimension of key. Only when both the phase key and 3D polarization key are correct, original messages can be recovered. We verify our proposal with both simulation and experiment evidences.

  10. QR code-based non-linear image encryption using Shearlet transform and spiral phase transform

    NASA Astrophysics Data System (ADS)

    Kumar, Ravi; Bhaduri, Basanta; Hennelly, Bryan

    2018-02-01

    In this paper, we propose a new quick response (QR) code-based non-linear technique for image encryption using Shearlet transform (ST) and spiral phase transform. The input image is first converted into a QR code and then scrambled using the Arnold transform. The scrambled image is then decomposed into five coefficients using the ST and the first Shearlet coefficient, C1 is interchanged with a security key before performing the inverse ST. The output after inverse ST is then modulated with a random phase mask and further spiral phase transformed to get the final encrypted image. The first coefficient, C1 is used as a private key for decryption. The sensitivity of the security keys is analysed in terms of correlation coefficient and peak signal-to noise ratio. The robustness of the scheme is also checked against various attacks such as noise, occlusion and special attacks. Numerical simulation results are shown in support of the proposed technique and an optoelectronic set-up for encryption is also proposed.

  11. Improving Inpatient Surveys: Web-Based Computer Adaptive Testing Accessed via Mobile Phone QR Codes

    PubMed Central

    2016-01-01

    Background The National Health Service (NHS) 70-item inpatient questionnaire surveys inpatients on their perceptions of their hospitalization experience. However, it imposes more burden on the patient than other similar surveys. The literature shows that computerized adaptive testing (CAT) based on item response theory can help shorten the item length of a questionnaire without compromising its precision. Objective Our aim was to investigate whether CAT can be (1) efficient with item reduction and (2) used with quick response (QR) codes scanned by mobile phones. Methods After downloading the 2008 inpatient survey data from the Picker Institute Europe website and analyzing the difficulties of this 70-item questionnaire, we used an author-made Excel program using the Rasch partial credit model to simulate 1000 patients’ true scores followed by a standard normal distribution. The CAT was compared to two other scenarios of answering all items (AAI) and the randomized selection method (RSM), as we investigated item length (efficiency) and measurement accuracy. The author-made Web-based CAT program for gathering patient feedback was effectively accessed from mobile phones by scanning the QR code. Results We found that the CAT can be more efficient for patients answering questions (ie, fewer items to respond to) than either AAI or RSM without compromising its measurement accuracy. A Web-based CAT inpatient survey accessed by scanning a QR code on a mobile phone was viable for gathering inpatient satisfaction responses. Conclusions With advances in technology, patients can now be offered alternatives for providing feedback about hospitalization satisfaction. This Web-based CAT is a possible option in health care settings for reducing the number of survey items, as well as offering an innovative QR code access. PMID:26935793

  12. Improving Inpatient Surveys: Web-Based Computer Adaptive Testing Accessed via Mobile Phone QR Codes.

    PubMed

    Chien, Tsair-Wei; Lin, Weir-Sen

    2016-03-02

    The National Health Service (NHS) 70-item inpatient questionnaire surveys inpatients on their perceptions of their hospitalization experience. However, it imposes more burden on the patient than other similar surveys. The literature shows that computerized adaptive testing (CAT) based on item response theory can help shorten the item length of a questionnaire without compromising its precision. Our aim was to investigate whether CAT can be (1) efficient with item reduction and (2) used with quick response (QR) codes scanned by mobile phones. After downloading the 2008 inpatient survey data from the Picker Institute Europe website and analyzing the difficulties of this 70-item questionnaire, we used an author-made Excel program using the Rasch partial credit model to simulate 1000 patients' true scores followed by a standard normal distribution. The CAT was compared to two other scenarios of answering all items (AAI) and the randomized selection method (RSM), as we investigated item length (efficiency) and measurement accuracy. The author-made Web-based CAT program for gathering patient feedback was effectively accessed from mobile phones by scanning the QR code. We found that the CAT can be more efficient for patients answering questions (ie, fewer items to respond to) than either AAI or RSM without compromising its measurement accuracy. A Web-based CAT inpatient survey accessed by scanning a QR code on a mobile phone was viable for gathering inpatient satisfaction responses. With advances in technology, patients can now be offered alternatives for providing feedback about hospitalization satisfaction. This Web-based CAT is a possible option in health care settings for reducing the number of survey items, as well as offering an innovative QR code access.

  13. LittleQuickWarp: an ultrafast image warping tool.

    PubMed

    Qu, Lei; Peng, Hanchuan

    2015-02-01

    Warping images into a standard coordinate space is critical for many image computing related tasks. However, for multi-dimensional and high-resolution images, an accurate warping operation itself is often very expensive in terms of computer memory and computational time. For high-throughput image analysis studies such as brain mapping projects, it is desirable to have high performance image warping tools that are compatible with common image analysis pipelines. In this article, we present LittleQuickWarp, a swift and memory efficient tool that boosts 3D image warping performance dramatically and at the same time has high warping quality similar to the widely used thin plate spline (TPS) warping. Compared to the TPS, LittleQuickWarp can improve the warping speed 2-5 times and reduce the memory consumption 6-20 times. We have implemented LittleQuickWarp as an Open Source plug-in program on top of the Vaa3D system (http://vaa3d.org). The source code and a brief tutorial can be found in the Vaa3D plugin source code repository. Copyright © 2014 Elsevier Inc. All rights reserved.

  14. Evaluation of three coding schemes designed for improved data communication

    NASA Technical Reports Server (NTRS)

    Snelsire, R. W.

    1974-01-01

    Three coding schemes designed for improved data communication are evaluated. Four block codes are evaluated relative to a quality function, which is a function of both the amount of data rejected and the error rate. The Viterbi maximum likelihood decoding algorithm as a decoding procedure is reviewed. This evaluation is obtained by simulating the system on a digital computer. Short constraint length rate 1/2 quick-look codes are studied, and their performance is compared to general nonsystematic codes.

  15. Semi-automated Modular Program Constructor for physiological modeling: Building cell and organ models.

    PubMed

    Jardine, Bartholomew; Raymond, Gary M; Bassingthwaighte, James B

    2015-01-01

    The Modular Program Constructor (MPC) is an open-source Java based modeling utility, built upon JSim's Mathematical Modeling Language (MML) ( http://www.physiome.org/jsim/) that uses directives embedded in model code to construct larger, more complicated models quickly and with less error than manually combining models. A major obstacle in writing complex models for physiological processes is the large amount of time it takes to model the myriad processes taking place simultaneously in cells, tissues, and organs. MPC replaces this task with code-generating algorithms that take model code from several different existing models and produce model code for a new JSim model. This is particularly useful during multi-scale model development where many variants are to be configured and tested against data. MPC encodes and preserves information about how a model is built from its simpler model modules, allowing the researcher to quickly substitute or update modules for hypothesis testing. MPC is implemented in Java and requires JSim to use its output. MPC source code and documentation are available at http://www.physiome.org/software/MPC/.

  16. Cellular and circuit properties supporting different sensory coding strategies in electric fish and other systems.

    PubMed

    Marsat, Gary; Longtin, André; Maler, Leonard

    2012-08-01

    Neural codes often seem tailored to the type of information they must carry. Here we contrast the encoding strategies for two different communication signals in electric fish and describe the underlying cellular and network properties that implement them. We compare an aggressive signal that needs to be quickly detected, to a courtship signal whose quality needs to be evaluated. The aggressive signal is encoded by synchronized bursts and a predictive feedback input is crucial in separating background noise from the communication signal. The courtship signal is accurately encoded through a heterogenous population response allowing the discrimination of signal differences. Most importantly we show that the same strategies are used in other systems arguing that they evolved similar solutions because they faced similar tasks. Copyright © 2012 Elsevier Ltd. All rights reserved.

  17. Use of QR and EAN-13 codes by older patients taking multiple medications for a safer use of medication.

    PubMed

    Mira, José Joaquín; Guilabert, Mercedes; Carrillo, Irene; Fernández, César; Vicente, Ma Asunción; Orozco-Beltrán, Domingo; Gil-Guillen, Vicente F

    2015-06-01

    Older persons following a prolonged complex drug regimen often make mistakes when taking their medication. Currently, the widespread use of tablets and smartphones has encouraged the development of applications to support self-management of medication. The aim of this study was to design, develop and assess an app that transforms medication-associated ean-13 (barcodes) and Quick Response codes (QR) into verbal instructions, to enable safer use of medication by the elderly patients taking multiple medications. Meetings were held in which participated a total of 61 patients. The results showed that patients appreciated the application and found it useful for safer use of medicines. The study results support the use of such technology to increase patient safety taking multiple medications safety. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  18. Quicklook overview of model changes in Melcor 2.2: Rev 6342 to Rev 9496

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Humphries, Larry L.

    2017-05-01

    MELCOR 2.2 is a significant official release of the MELCOR code with many new models and model improvements. This report provides the code user with a quick review and characterization of new models added, changes to existing models, the effect of code changes during this code development cycle (rev 6342 to rev 9496), a preview of validation results with this code version. More detailed information is found in the code Subversion logs as well as the User Guide and Reference Manuals.

  19. Smartphone tool to collect repeated 24 h dietary recall data in Nepal.

    PubMed

    Harris-Fry, Helen; Beard, B James; Harrisson, Tom; Paudel, Puskar; Shrestha, Niva; Jha, Sonali; Shrestha, Bhim P; Manandhar, Dharma S; Costello, Anthony; Saville, Naomi M

    2018-02-01

    To outline the development of a smartphone-based tool to collect thrice-repeated 24 h dietary recall data in rural Nepal, and to describe energy intakes, common errors and researchers' experiences using the tool. We designed a novel tool to collect multi-pass 24 h dietary recalls in rural Nepal by combining the use of a CommCare questionnaire on smartphones, a paper form, a QR (quick response)-coded list of foods and a photographic atlas of portion sizes. Twenty interviewers collected dietary data on three non-consecutive days per respondent, with three respondents per household. Intakes were converted into nutrients using databases on nutritional composition of foods, recipes and portion sizes. Dhanusha and Mahottari districts, Nepal. Pregnant women, their mothers-in-law and male household heads. Energy intakes assessed in 150 households; data corrections and our experiences reported from 805 households and 6765 individual recalls. Dietary intake estimates gave plausible values, with male household heads appearing to have higher energy intakes (median (25th-75th centile): 12 079 (9293-14 108) kJ/d) than female members (8979 (7234-11 042) kJ/d for pregnant women). Manual editing of data was required when interviewers mistook portions for food codes and for coding items not on the food list. Smartphones enabled quick monitoring of data and interviewer performance, but we initially faced technical challenges with CommCare forms crashing. With sufficient time dedicated to development and pre-testing, this novel smartphone-based tool provides a useful method to collect data. Future work is needed to further validate this tool and adapt it for other contexts.

  20. DNA Barcode Goes Two-Dimensions: DNA QR Code Web Server

    PubMed Central

    Li, Huan; Xing, Hang; Liang, Dong; Jiang, Kun; Pang, Xiaohui; Song, Jingyuan; Chen, Shilin

    2012-01-01

    The DNA barcoding technology uses a standard region of DNA sequence for species identification and discovery. At present, “DNA barcode” actually refers to DNA sequences, which are not amenable to information storage, recognition, and retrieval. Our aim is to identify the best symbology that can represent DNA barcode sequences in practical applications. A comprehensive set of sequences for five DNA barcode markers ITS2, rbcL, matK, psbA-trnH, and CO1 was used as the test data. Fifty-three different types of one-dimensional and ten two-dimensional barcode symbologies were compared based on different criteria, such as coding capacity, compression efficiency, and error detection ability. The quick response (QR) code was found to have the largest coding capacity and relatively high compression ratio. To facilitate the further usage of QR code-based DNA barcodes, a web server was developed and is accessible at http://qrfordna.dnsalias.org. The web server allows users to retrieve the QR code for a species of interests, convert a DNA sequence to and from a QR code, and perform species identification based on local and global sequence similarities. In summary, the first comprehensive evaluation of various barcode symbologies has been carried out. The QR code has been found to be the most appropriate symbology for DNA barcode sequences. A web server has also been constructed to allow biologists to utilize QR codes in practical DNA barcoding applications. PMID:22574113

  1. An In vitro evaluation of the reliability of QR code denture labeling technique.

    PubMed

    Poovannan, Sindhu; Jain, Ashish R; Krishnan, Cakku Jalliah Venkata; Chandran, Chitraa R

    2016-01-01

    Positive identification of the dead after accidents and disasters through labeled dentures plays a key role in forensic scenario. A number of denture labeling methods are available, and studies evaluating their reliability under drastic conditions are vital. This study was conducted to evaluate the reliability of QR (Quick Response) Code labeled at various depths in heat-cured acrylic blocks after acid treatment, heat treatment (burns), and fracture in forensics. It was an in vitro study. This study included 160 specimens of heat-cured acrylic blocks (1.8 cm × 1.8 cm) and these were divided into 4 groups (40 samples per group). QR Codes were incorporated in the samples using clear acrylic sheet and they were assessed for reliability under various depths, acid, heat, and fracture. Data were analyzed using Chi-square test, test of proportion. The QR Code inclusion technique was reliable under various depths of acrylic sheet, acid (sulfuric acid 99%, hydrochloric acid 40%) and heat (up to 370°C). Results were variable with fracture of QR Code labeled acrylic blocks. Within the limitations of the study, by analyzing the results, it was clearly indicated that the QR Code technique was reliable under various depths of acrylic sheet, acid, and heat (370°C). Effectiveness varied in fracture and depended on the level of distortion. This study thus suggests that QR Code is an effective and simpler denture labeling method.

  2. 77 FR 17462 - Notice of Submission for OMB Review; Institute of Education Sciences; Quick Response Information...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-26

    ... DEPARTMENT OF EDUCATION Notice of Submission for OMB Review; Institute of Education Sciences; Quick Response Information System (QRIS) 2012-2015 System Clearance SUMMARY: The National Center for Education Statistics (NCES) Quick Response Information System (QRIS) consists of the Fast Response Survey...

  3. Dream to Predict? REM Dreaming as Prospective Coding

    PubMed Central

    Llewellyn, Sue

    2016-01-01

    The dream as prediction seems inherently improbable. The bizarre occurrences in dreams never characterize everyday life. Dreams do not come true! But assuming that bizarreness negates expectations may rest on a misunderstanding of how the predictive brain works. In evolutionary terms, the ability to rapidly predict what sensory input implies—through expectations derived from discerning patterns in associated past experiences—would have enhanced fitness and survival. For example, food and water are essential for survival, associating past experiences (to identify location patterns) predicts where they can be found. Similarly, prediction may enable predator identification from what would have been only a fleeting and ambiguous stimulus—without prior expectations. To confront the many challenges associated with natural settings, visual perception is vital for humans (and most mammals) and often responses must be rapid. Predictive coding during wake may, therefore, be based on unconscious imagery so that visual perception is maintained and appropriate motor actions triggered quickly. Speed may also dictate the form of the imagery. Bizarreness, during REM dreaming, may result from a prospective code fusing phenomena with the same meaning—within a particular context. For example, if the context is possible predation, from the perspective of the prey two different predators can both mean the same (i.e., immediate danger) and require the same response (e.g., flight). Prospective coding may also prune redundancy from memories, to focus the image on the contextually-relevant elements only, thus, rendering the non-relevant phenomena indeterminate—another aspect of bizarreness. In sum, this paper offers an evolutionary take on REM dreaming as a form of prospective coding which identifies a probabilistic pattern in past events. This pattern is portrayed in an unconscious, associative, sensorimotor image which may support cognition in wake through being mobilized as a predictive code. A particular dream illustrates. PMID:26779078

  4. Semantic Integration and Age of Acquisition Effects in Code-Blend Comprehension

    ERIC Educational Resources Information Center

    Giezen, Marcel R.; Emmorey, Karen

    2016-01-01

    Semantic and lexical decision tasks were used to investigate the mechanisms underlying code-blend facilitation: the finding that hearing bimodal bilinguals comprehend signs in American Sign Language (ASL) and spoken English words more quickly when they are presented together simultaneously than when each is presented alone. More robust…

  5. Quality Traceability System of Traditional Chinese Medicine Based on Two Dimensional Barcode Using Mobile Intelligent Technology.

    PubMed

    Cai, Yong; Li, Xiwen; Wang, Runmiao; Yang, Qing; Li, Peng; Hu, Hao

    2016-01-01

    Currently, the chemical fingerprint comparison and analysis is mainly based on professional equipment and software, it's expensive and inconvenient. This study aims to integrate QR (Quick Response) code with quality data and mobile intelligent technology to develop a convenient query terminal for tracing quality in the whole industrial chain of TCM (traditional Chinese medicine). Three herbal medicines were randomly selected and their chemical two-dimensional barcode (2D) barcodes fingerprints were constructed. Smartphone application (APP) based on Android system was developed to read initial data of 2D chemical barcodes, and compared multiple fingerprints from different batches of same species or different species. It was demonstrated that there were no significant differences between original and scanned TCM chemical fingerprints. Meanwhile, different TCM chemical fingerprint QR codes could be rendered in the same coordinate and showed the differences very intuitively. To be able to distinguish the variations of chemical fingerprint more directly, linear interpolation angle cosine similarity algorithm (LIACSA) was proposed to get similarity ratio. This study showed that QR codes can be used as an effective information carrier to transfer quality data. Smartphone application can rapidly read quality information in QR codes and convert data into TCM chemical fingerprints.

  6. Micromechanics Analysis Code Post-Processing (MACPOST) User Guide. 1.0

    NASA Technical Reports Server (NTRS)

    Goldberg, Robert K.; Comiskey, Michele D.; Bednarcyk, Brett A.

    1999-01-01

    As advanced composite materials have gained wider usage. the need for analytical models and computer codes to predict the thermomechanical deformation response of these materials has increased significantly. Recently, a micromechanics technique called the generalized method of cells (GMC) has been developed, which has the capability to fulfill this -oal. Tc provide a framework for GMC, the Micromechanics Analysis Code with Generalized Method of Cells (MAC/GMC) has been developed. As MAC/GMC has been updated, significant improvements have been made to the post-processing capabilities of the code. Through the MACPOST program, which operates directly within the MSC/PATRAN graphical pre- and post-processing package, a direct link between the analysis capabilities of MAC/GMC and the post-processing capabilities of MSC/PATRAN has been established. MACPOST has simplified the production, printing. and exportation of results for unit cells analyzed by MAC/GMC. MACPOST allows different micro-level quantities to be plotted quickly and easily in contour plots. In addition, meaningful data for X-Y plots can be examined. MACPOST thus serves as an important analysis and visualization tool for the macro- and micro-level data generated by MAC/GMC. This report serves as the user's manual for the MACPOST program.

  7. LTCP 2D Graphical User Interface. Application Description and User's Guide

    NASA Technical Reports Server (NTRS)

    Ball, Robert; Navaz, Homayun K.

    1996-01-01

    A graphical user interface (GUI) written for NASA's LTCP (Liquid Thrust Chamber Performance) 2 dimensional computational fluid dynamic code is described. The GUI is written in C++ for a desktop personal computer running under a Microsoft Windows operating environment. Through the use of common and familiar dialog boxes, features, and tools, the user can easily and quickly create and modify input files for the LTCP code. In addition, old input files used with the LTCP code can be opened and modified using the GUI. The application is written in C++ for a desktop personal computer running under a Microsoft Windows operating environment. The program and its capabilities are presented, followed by a detailed description of each menu selection and the method of creating an input file for LTCP. A cross reference is included to help experienced users quickly find the variables which commonly need changes. Finally, the system requirements and installation instructions are provided.

  8. Cloud Fingerprinting: Using Clock Skews To Determine Co Location Of Virtual Machines

    DTIC Science & Technology

    2016-09-01

    DISTRIBUTION CODE 13. ABSTRACT (maximum 200 words) Cloud computing has quickly revolutionized computing practices of organizations, to include the Department of... Cloud computing has quickly revolutionized computing practices of organizations, to in- clude the Department of Defense. However, security concerns...vi Table of Contents 1 Introduction 1 1.1 Proliferation of Cloud Computing . . . . . . . . . . . . . . . . . . 1 1.2 Problem Statement

  9. Optically secured information retrieval using two authenticated phase-only masks.

    PubMed

    Wang, Xiaogang; Chen, Wen; Mei, Shengtao; Chen, Xudong

    2015-10-23

    We propose an algorithm for jointly designing two phase-only masks (POMs) that allow for the encryption and noise-free retrieval of triple images. The images required for optical retrieval are first stored in quick-response (QR) codes for noise-free retrieval and flexible readout. Two sparse POMs are respectively calculated from two different images used as references for authentication based on modified Gerchberg-Saxton algorithm (GSA) and pixel extraction, and are then used as support constraints in a modified double-phase retrieval algorithm (MPRA), together with the above-mentioned QR codes. No visible information about the target images or the reference images can be obtained from each of these authenticated POMs. This approach allows users to authenticate the two POMs used for image reconstruction without visual observation of the reference images. It also allows user to friendly access and readout with mobile devices.

  10. Optically secured information retrieval using two authenticated phase-only masks

    PubMed Central

    Wang, Xiaogang; Chen, Wen; Mei, Shengtao; Chen, Xudong

    2015-01-01

    We propose an algorithm for jointly designing two phase-only masks (POMs) that allow for the encryption and noise-free retrieval of triple images. The images required for optical retrieval are first stored in quick-response (QR) codes for noise-free retrieval and flexible readout. Two sparse POMs are respectively calculated from two different images used as references for authentication based on modified Gerchberg-Saxton algorithm (GSA) and pixel extraction, and are then used as support constraints in a modified double-phase retrieval algorithm (MPRA), together with the above-mentioned QR codes. No visible information about the target images or the reference images can be obtained from each of these authenticated POMs. This approach allows users to authenticate the two POMs used for image reconstruction without visual observation of the reference images. It also allows user to friendly access and readout with mobile devices. PMID:26494213

  11. Optically secured information retrieval using two authenticated phase-only masks

    NASA Astrophysics Data System (ADS)

    Wang, Xiaogang; Chen, Wen; Mei, Shengtao; Chen, Xudong

    2015-10-01

    We propose an algorithm for jointly designing two phase-only masks (POMs) that allow for the encryption and noise-free retrieval of triple images. The images required for optical retrieval are first stored in quick-response (QR) codes for noise-free retrieval and flexible readout. Two sparse POMs are respectively calculated from two different images used as references for authentication based on modified Gerchberg-Saxton algorithm (GSA) and pixel extraction, and are then used as support constraints in a modified double-phase retrieval algorithm (MPRA), together with the above-mentioned QR codes. No visible information about the target images or the reference images can be obtained from each of these authenticated POMs. This approach allows users to authenticate the two POMs used for image reconstruction without visual observation of the reference images. It also allows user to friendly access and readout with mobile devices.

  12. Mock Code: A Code Blue Scenario Requested by and Developed for Registered Nurses

    PubMed Central

    Rideout, Janice; Pritchett-Kelly, Sherry; McDonald, Melissa; Mullins-Richards, Paula; Dubrowski, Adam

    2016-01-01

    The use of simulation in medical training is quickly becoming more common, with applications in emergency, surgical, and nursing education. Recently, registered nurses working in surgical inpatient units requested a mock code simulation to practice skills, improve knowledge, and build self-confidence in a safe and controlled environment. A simulation scenario using a high-fidelity mannequin was developed and will be discussed herein. PMID:28123919

  13. 7 CFR 1486.206 - What is the Quick Response Marketing Fund?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 10 2011-01-01 2011-01-01 false What is the Quick Response Marketing Fund? 1486.206... Eligibility, Applications, and Funding § 1486.206 What is the Quick Response Marketing Fund? (a) This fund was... responsiveness to time-sensitive marketing problems or opportunities, such as a change in an import regime or the...

  14. Aviation System Analysis Capability Quick Response System Report for Fiscal Year 1998

    NASA Technical Reports Server (NTRS)

    Ege, Russell; Villani, James; Ritter, Paul

    1999-01-01

    This document presents the additions and modifications made to the Quick Response System (QRS) in FY 1998 in support of the ASAC QRS development effort. this Document builds upon the Aviation System Analysis Capability Quick Responses System Report for Fiscal Year 1997.

  15. An In vitro evaluation of the reliability of QR code denture labeling technique

    PubMed Central

    Poovannan, Sindhu; Jain, Ashish R.; Krishnan, Cakku Jalliah Venkata; Chandran, Chitraa R.

    2016-01-01

    Statement of Problem: Positive identification of the dead after accidents and disasters through labeled dentures plays a key role in forensic scenario. A number of denture labeling methods are available, and studies evaluating their reliability under drastic conditions are vital. Aim: This study was conducted to evaluate the reliability of QR (Quick Response) Code labeled at various depths in heat-cured acrylic blocks after acid treatment, heat treatment (burns), and fracture in forensics. It was an in vitro study. Materials and Methods: This study included 160 specimens of heat-cured acrylic blocks (1.8 cm × 1.8 cm) and these were divided into 4 groups (40 samples per group). QR Codes were incorporated in the samples using clear acrylic sheet and they were assessed for reliability under various depths, acid, heat, and fracture. Data were analyzed using Chi-square test, test of proportion. Results: The QR Code inclusion technique was reliable under various depths of acrylic sheet, acid (sulfuric acid 99%, hydrochloric acid 40%) and heat (up to 370°C). Results were variable with fracture of QR Code labeled acrylic blocks. Conclusion: Within the limitations of the study, by analyzing the results, it was clearly indicated that the QR Code technique was reliable under various depths of acrylic sheet, acid, and heat (370°C). Effectiveness varied in fracture and depended on the level of distortion. This study thus suggests that QR Code is an effective and simpler denture labeling method. PMID:28123284

  16. HERCULES: A Pattern Driven Code Transformation System

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kartsaklis, Christos; Hernandez, Oscar R; Hsu, Chung-Hsing

    2012-01-01

    New parallel computers are emerging, but developing efficient scientific code for them remains difficult. A scientist must manage not only the science-domain complexity but also the performance-optimization complexity. HERCULES is a code transformation system designed to help the scientist to separate the two concerns, which improves code maintenance, and facilitates performance optimization. The system combines three technologies, code patterns, transformation scripts and compiler plugins, to provide the scientist with an environment to quickly implement code transformations that suit his needs. Unlike existing code optimization tools, HERCULES is unique in its focus on user-level accessibility. In this paper we discuss themore » design, implementation and an initial evaluation of HERCULES.« less

  17. A novel use of QR code stickers after orthopaedic cast application.

    PubMed

    Gough, A T; Fieraru, G; Gaffney, Pav; Butler, M; Kincaid, R J; Middleton, R G

    2017-07-01

    INTRODUCTION We present a novel solution to ensure that information and contact details are always available to patients while in cast. An information sticker containing both telephone numbers and a Quick Response (QR) code is applied to the cast. When scanned with a smartphone, the QR code loads the plaster team's webpage. This contains information and videos about cast care, complications and enhancing recovery. METHODS A sticker was designed and applied to all synthetic casts fitted in our fracture clinic. On cast removal, patients completed a questionnaire about the sticker. A total of 101 patients were surveyed between November 2015 and February 2016. The questionnaire comprised ten binary choice questions. RESULTS The vast majority (97%) of patients had the sticker still on their cast when they returned to clinic for cast removal. Eighty-four per cent of all patients felt reassured by the presence of the QR code sticker. Nine per cent used the contact details on the cast to seek advice. Over half (56%) had a smartphone and a third (33%) of these scanned the QR code. Of those who scanned the code, 95% found the information useful. CONCLUSIONS This study indicates that use of a QR code reassures patients and is an effective tool in the proactive management of potential cast problems. The QR code sticker is now applied to all casts across our trust. In line with NHS England's Five Year Forward View calling for enhanced use of smartphone technology, our trust is continuing to expand its portfolio of patient information accessible via QR codes. Other branches of medicine may benefit from incorporating QR codes as portals to access such information.

  18. Processing of on-board recorded data for quick analysis of aircraft performance. [rotor systems research aircraft

    NASA Technical Reports Server (NTRS)

    Michaud, N. H.

    1979-01-01

    A system of independent computer programs for the processing of digitized pulse code modulated (PCM) and frequency modulated (FM) data is described. Information is stored in a set of random files and accessed to produce both statistical and graphical output. The software system is designed primarily to present these reports within a twenty-four hour period for quick analysis of the helicopter's performance.

  19. 7 CFR 1486.206 - What is the Quick Response Marketing Fund?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 10 2013-01-01 2013-01-01 false What is the Quick Response Marketing Fund? 1486.206... Funding § 1486.206 What is the Quick Response Marketing Fund? (a) This fund was established to address... time-sensitive marketing problems or opportunities, such as a change in an import regime or the removal...

  20. 7 CFR 1486.206 - What is the Quick Response Marketing Fund?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 10 2014-01-01 2014-01-01 false What is the Quick Response Marketing Fund? 1486.206... Funding § 1486.206 What is the Quick Response Marketing Fund? (a) This fund was established to address... time-sensitive marketing problems or opportunities, such as a change in an import regime or the removal...

  1. 7 CFR 1486.206 - What is the Quick Response Marketing Fund?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 10 2012-01-01 2012-01-01 false What is the Quick Response Marketing Fund? 1486.206... Funding § 1486.206 What is the Quick Response Marketing Fund? (a) This fund was established to address... time-sensitive marketing problems or opportunities, such as a change in an import regime or the removal...

  2. An embedded barcode for "connected" malaria rapid diagnostic tests.

    PubMed

    Scherr, Thomas F; Gupta, Sparsh; Wright, David W; Haselton, Frederick R

    2017-03-29

    Many countries are shifting their efforts from malaria control to disease elimination. New technologies will be necessary to meet the more stringent demands of elimination campaigns, including improved quality control of malaria diagnostic tests, as well as an improved means for communicating test results among field healthcare workers, test manufacturers, and national ministries of health. In this report, we describe and evaluate an embedded barcode within standard rapid diagnostic tests as one potential solution. This information-augmented diagnostic test operates on the familiar principles of traditional lateral flow assays and simply replaces the control line with a control grid patterned in the shape of a QR (quick response) code. After the test is processed, the QR code appears on both positive or negative tests. In this report we demonstrate how this multipurpose code can be used not only to fulfill the control line role of test validation, but also to embed test manufacturing details, serve as a trigger for image capture, enable registration for image analysis, and correct for lighting effects. An accompanying mobile phone application automatically captures an image of the test when the QR code is recognized, decodes the QR code, performs image processing to determine the concentration of the malarial biomarker histidine-rich protein 2 at the test line, and transmits the test results and QR code payload to a secure web portal. This approach blends automated, sub-nanomolar biomarker detection, with near real-time reporting to provide quality assurance data that will help to achieve malaria elimination.

  3. Anisotropic Resistivity Forward Modelling Using Automatic Generated Higher-order Finite Element Codes

    NASA Astrophysics Data System (ADS)

    Wang, W.; Liu, J.

    2016-12-01

    Forward modelling is the general way to obtain responses of geoelectrical structures. Field investigators might find it useful for planning surveys and choosing optimal electrode configurations with respect to their targets. During the past few decades much effort has been put into the development of numerical forward codes, such as integral equation method, finite difference method and finite element method. Nowadays, most researchers prefer the finite element method (FEM) for its flexible meshing scheme, which can handle models with complex geometry. Resistivity Modelling with commercial sofewares such as ANSYS and COMSOL is convenient, but like working with a black box. Modifying the existed codes or developing new codes is somehow a long period. We present a new way to obtain resistivity forward modelling codes quickly, which is based on the commercial sofeware FEPG (Finite element Program Generator). Just with several demanding scripts, FEPG could generate FORTRAN program framework which can easily be altered to adjust our targets. By supposing the electric potential is quadratic in each element of a two-layer model, we obtain quite accurate results with errors less than 1%, while more than 5% errors could appear by linear FE codes. The anisotropic half-space model is supposed to concern vertical distributed fractures. The measured apparent resistivities along the fractures are bigger than results from its orthogonal direction, which are opposite of the true resistivities. Interpretation could be misunderstood if this anisotropic paradox is ignored. The technique we used can obtain scientific codes in a short time. The generated powerful FORTRAN codes could reach accurate results by higher-order assumption and can handle anisotropy to make better interpretations. The method we used could be expand easily to other domain where FE codes are needed.

  4. Quality Traceability System of Traditional Chinese Medicine Based on Two Dimensional Barcode Using Mobile Intelligent Technology

    PubMed Central

    Cai, Yong; Li, Xiwen; Wang, Runmiao; Yang, Qing; Li, Peng; Hu, Hao

    2016-01-01

    Currently, the chemical fingerprint comparison and analysis is mainly based on professional equipment and software, it’s expensive and inconvenient. This study aims to integrate QR (Quick Response) code with quality data and mobile intelligent technology to develop a convenient query terminal for tracing quality in the whole industrial chain of TCM (traditional Chinese medicine). Three herbal medicines were randomly selected and their chemical two-dimensional barcode (2D) barcodes fingerprints were constructed. Smartphone application (APP) based on Android system was developed to read initial data of 2D chemical barcodes, and compared multiple fingerprints from different batches of same species or different species. It was demonstrated that there were no significant differences between original and scanned TCM chemical fingerprints. Meanwhile, different TCM chemical fingerprint QR codes could be rendered in the same coordinate and showed the differences very intuitively. To be able to distinguish the variations of chemical fingerprint more directly, linear interpolation angle cosine similarity algorithm (LIACSA) was proposed to get similarity ratio. This study showed that QR codes can be used as an effective information carrier to transfer quality data. Smartphone application can rapidly read quality information in QR codes and convert data into TCM chemical fingerprints. PMID:27780256

  5. Topic models: A novel method for modeling couple and family text data

    PubMed Central

    Atkins, David C.; Rubin, Tim N.; Steyvers, Mark; Doeden, Michelle A.; Baucom, Brian R.; Christensen, Andrew

    2012-01-01

    Couple and family researchers often collect open-ended linguistic data – either through free response questionnaire items or transcripts of interviews or therapy sessions. Because participant's responses are not forced into a set number of categories, text-based data can be very rich and revealing of psychological processes. At the same time it is highly unstructured and challenging to analyze. Within family psychology analyzing text data typically means applying a coding system, which can quantify text data but also has several limitations, including the time needed for coding, difficulties with inter-rater reliability, and defining a priori what should be coded. The current article presents an alternative method for analyzing text data called topic models (Steyvers & Griffiths, 2006), which has not yet been applied within couple and family psychology. Topic models have similarities with factor analysis and cluster analysis in that topic models identify underlying clusters of words with semantic similarities (i.e., the “topics”). In the present article, a non-technical introduction to topic models is provided, highlighting how these models can be used for text exploration and indexing (e.g., quickly locating text passages that share semantic meaning) and how output from topic models can be used to predict behavioral codes or other types of outcomes. Throughout the article a collection of transcripts from a large couple therapy trial (Christensen et al., 2004) is used as example data to highlight potential applications. Practical resources for learning more about topic models and how to apply them are discussed. PMID:22888778

  6. Topic models: a novel method for modeling couple and family text data.

    PubMed

    Atkins, David C; Rubin, Timothy N; Steyvers, Mark; Doeden, Michelle A; Baucom, Brian R; Christensen, Andrew

    2012-10-01

    Couple and family researchers often collect open-ended linguistic data-either through free-response questionnaire items, or transcripts of interviews or therapy sessions. Because participants' responses are not forced into a set number of categories, text-based data can be very rich and revealing of psychological processes. At the same time, it is highly unstructured and challenging to analyze. Within family psychology, analyzing text data typically means applying a coding system, which can quantify text data but also has several limitations, including the time needed for coding, difficulties with interrater reliability, and defining a priori what should be coded. The current article presents an alternative method for analyzing text data called topic models (Steyvers & Griffiths, 2006), which has not yet been applied within couple and family psychology. Topic models have similarities to factor analysis and cluster analysis in that they identify underlying clusters of words with semantic similarities (i.e., the "topics"). In the present article, a nontechnical introduction to topic models is provided, highlighting how these models can be used for text exploration and indexing (e.g., quickly locating text passages that share semantic meaning) and how output from topic models can be used to predict behavioral codes or other types of outcomes. Throughout the article, a collection of transcripts from a large couple-therapy trial (Christensen et al., 2004) is used as example data to highlight potential applications. Practical resources for learning more about topic models and how to apply them are discussed. (PsycINFO Database Record (c) 2012 APA, all rights reserved).

  7. Learning a Nonmediated Route for Response Selection in Task Switching

    PubMed Central

    Schneider, Darryl W.; Logan, Gordon D.

    2015-01-01

    Two modes of response selection—a mediated route involving categorization and a nonmediated route involving instance-based memory retrieval—have been proposed to explain response congruency effects in task-switching situations. In the present study, we sought a better understanding of the development and characteristics of the nonmediated route. In two experiments involving training and transfer phases, we investigated practice effects at the level of individual target presentations, transfer effects associated with changing category–response mappings, target-specific effects from comparisons of old and new targets during transfer, and the percentage of early responses associated with task-nonspecific response selection (the target preceded the task cue on every trial). The training results suggested that the nonmediated route is quickly learned in the context of target–cue order and becomes increasingly involved in response selection with practice. The transfer results suggested that the target–response instances underlying the nonmediated route involve abstract response labels coding response congruency that can be rapidly remapped to alternative responses but not rewritten when category–response mappings change after practice. Implications for understanding the nonmediated route and its relationship with the mediated route are discussed. PMID:25663003

  8. [Code of civil procedure for medical workers -the essential principles of proceedings and expediting of trials-].

    PubMed

    Kageyama, Kyoko; Jimba, Koichi; Hashimoto, Satoru

    2013-04-01

    Code of civil procedure is started when a plaintiff appeals to the law. Conversely, if a suit is not appealed, it is not started. We explain the essential principles of the code of civil procedure, and present systems associated with expediting trials (a brief, preliminary oral arguments, preparatory proceedings, inquiry to opponent, organized proceedings, technical adviser system, etc.). Amendment of law is repeated for the purpose of aiming suitably expediting trials. We should utilize the present code of civil procedure suitably, and expect the quick conclusion of trials.

  9. Social Media, Education and Data Sharing

    NASA Astrophysics Data System (ADS)

    King, T. A.; Walker, R. J.; Masters, A.

    2011-12-01

    Social media is a blending of technology and social interactions which allows for the creation and exchange of user-generated content. Social media started as conversations between groups of people, now companies are using social media to communicate with customers and politicians use it to communicate with their constituents. Social media is now finding uses in the science communities. This adoption is driven by the expectation of students that technology will be an integral part of their research and that it will match the technology they use in their social lifes. Students are using social media to keep informed and collaborate with others. They have also replaced notepads with smart mobile devices. We have been introducing social media components into Virtual Observatories as a way to quickly access and exchange information with a tap or a click. We discuss the use of Quick Response (QR) codes, Digital Object Identifiers (DOIs), unique identifiers, Twitter, Facebook and tiny URL redirects as ways to enable easier sharing of data and information. We also discuss what services and features are needed in a Virtual Observatory to make data sharing with social media possible.

  10. Bio-inspired approach to multistage image processing

    NASA Astrophysics Data System (ADS)

    Timchenko, Leonid I.; Pavlov, Sergii V.; Kokryatskaya, Natalia I.; Poplavska, Anna A.; Kobylyanska, Iryna M.; Burdenyuk, Iryna I.; Wójcik, Waldemar; Uvaysova, Svetlana; Orazbekov, Zhassulan; Kashaganova, Gulzhan

    2017-08-01

    Multistage integration of visual information in the brain allows people to respond quickly to most significant stimuli while preserving the ability to recognize small details in the image. Implementation of this principle in technical systems can lead to more efficient processing procedures. The multistage approach to image processing, described in this paper, comprises main types of cortical multistage convergence. One of these types occurs within each visual pathway and the other between the pathways. This approach maps input images into a flexible hierarchy which reflects the complexity of the image data. The procedures of temporal image decomposition and hierarchy formation are described in mathematical terms. The multistage system highlights spatial regularities, which are passed through a number of transformational levels to generate a coded representation of the image which encapsulates, in a computer manner, structure on different hierarchical levels in the image. At each processing stage a single output result is computed to allow a very quick response from the system. The result is represented as an activity pattern, which can be compared with previously computed patterns on the basis of the closest match.

  11. Avatar DNA Nanohybrid System in Chip-on-a-Phone

    NASA Astrophysics Data System (ADS)

    Park, Dae-Hwan; Han, Chang Jo; Shul, Yong-Gun; Choy, Jin-Ho

    2014-05-01

    Long admired for informational role and recognition function in multidisciplinary science, DNA nanohybrids have been emerging as ideal materials for molecular nanotechnology and genetic information code. Here, we designed an optical machine-readable DNA icon on microarray, Avatar DNA, for automatic identification and data capture such as Quick Response and ColorZip codes. Avatar icon is made of telepathic DNA-DNA hybrids inscribed on chips, which can be identified by camera of smartphone with application software. Information encoded in base-sequences can be accessed by connecting an off-line icon to an on-line web-server network to provide message, index, or URL from database library. Avatar DNA is then converged with nano-bio-info-cogno science: each building block stands for inorganic nanosheets, nucleotides, digits, and pixels. This convergence could address item-level identification that strengthens supply-chain security for drug counterfeits. It can, therefore, provide molecular-level vision through mobile network to coordinate and integrate data management channels for visual detection and recording.

  12. Inkjet-compatible single-component polydiacetylene precursors for thermochromic paper sensors.

    PubMed

    Yoon, Bora; Shin, Hyora; Kang, Eun-Mi; Cho, Dae Won; Shin, Kayeong; Chung, Hoeil; Lee, Chan Woo; Kim, Jong-Man

    2013-06-12

    Inkjet-printable diacetylene (DA) supramolecules, which can be dispersed in water without using additional surfactants, have been developed. The supramolecules are generated from DA monomers that contain bisurea groups, which are capable of forming hydrogen-bonding networks, and hydrophilic oligoethylene oxide moieties. Because of suitable size distribution and stability characteristics, the single DA component ink can be readily transferred to paper substrates by utilizing a common office inkjet printer. UV irradiation of the DA-printed paper results in generation of blue-colored polydiacetylene (PDA) images, which show reversible thermochromic transitions in specific temperature ranges. Inkjet-printed PDAs, in the format of a two-dimensional (2D) quick response (QR) code on a real parking ticket, serve as a dual anticounterfeiting system that combines easy decoding of the QR code and colorimetric PDA reversibility for validating the authenticity of the tickets. This single-component ink system has great potential for use in paper-based devices, temperature sensors, and anticounterfeiting barcodes.

  13. Avatar DNA Nanohybrid System in Chip-on-a-Phone

    PubMed Central

    Park, Dae-Hwan; Han, Chang Jo; Shul, Yong-Gun; Choy, Jin-Ho

    2014-01-01

    Long admired for informational role and recognition function in multidisciplinary science, DNA nanohybrids have been emerging as ideal materials for molecular nanotechnology and genetic information code. Here, we designed an optical machine-readable DNA icon on microarray, Avatar DNA, for automatic identification and data capture such as Quick Response and ColorZip codes. Avatar icon is made of telepathic DNA-DNA hybrids inscribed on chips, which can be identified by camera of smartphone with application software. Information encoded in base-sequences can be accessed by connecting an off-line icon to an on-line web-server network to provide message, index, or URL from database library. Avatar DNA is then converged with nano-bio-info-cogno science: each building block stands for inorganic nanosheets, nucleotides, digits, and pixels. This convergence could address item-level identification that strengthens supply-chain security for drug counterfeits. It can, therefore, provide molecular-level vision through mobile network to coordinate and integrate data management channels for visual detection and recording. PMID:24824876

  14. Nonlinear QR code based optical image encryption using spiral phase transform, equal modulus decomposition and singular value decomposition

    NASA Astrophysics Data System (ADS)

    Kumar, Ravi; Bhaduri, Basanta; Nishchal, Naveen K.

    2018-01-01

    In this study, we propose a quick response (QR) code based nonlinear optical image encryption technique using spiral phase transform (SPT), equal modulus decomposition (EMD) and singular value decomposition (SVD). First, the primary image is converted into a QR code and then multiplied with a spiral phase mask (SPM). Next, the product is spiral phase transformed with particular spiral phase function, and further, the EMD is performed on the output of SPT, which results into two complex images, Z 1 and Z 2. Among these, Z 1 is further Fresnel propagated with distance d, and Z 2 is reserved as a decryption key. Afterwards, SVD is performed on Fresnel propagated output to get three decomposed matrices i.e. one diagonal matrix and two unitary matrices. The two unitary matrices are modulated with two different SPMs and then, the inverse SVD is performed using the diagonal matrix and modulated unitary matrices to get the final encrypted image. Numerical simulation results confirm the validity and effectiveness of the proposed technique. The proposed technique is robust against noise attack, specific attack, and brutal force attack. Simulation results are presented in support of the proposed idea.

  15. The Scientific Image in Behavior Analysis.

    PubMed

    Keenan, Mickey

    2016-05-01

    Throughout the history of science, the scientific image has played a significant role in communication. With recent developments in computing technology, there has been an increase in the kinds of opportunities now available for scientists to communicate in more sophisticated ways. Within behavior analysis, though, we are only just beginning to appreciate the importance of going beyond the printing press to elucidate basic principles of behavior. The aim of this manuscript is to stimulate appreciation of both the role of the scientific image and the opportunities provided by a quick response code (QR code) for enhancing the functionality of the printed page. I discuss the limitations of imagery in behavior analysis ("Introduction"), and I show examples of what can be done with animations and multimedia for teaching philosophical issues that arise when teaching about private events ("Private Events 1 and 2"). Animations are also useful for bypassing ethical issues when showing examples of challenging behavior ("Challenging Behavior"). Each of these topics can be accessed only by scanning the QR code provided. This contingency has been arranged to help the reader embrace this new technology. In so doing, I hope to show its potential for going beyond the limitations of the printing press.

  16. New techniques in neutron data measurements above 30 MeV

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lisowski, P.W.; Haight, R.C.

    1991-01-01

    Recent developments in experimental facilities have enabled new techniques for measurements of neutron interactions above 30 MeV. Foremost is the development of both monoenergetic and continuous neutron sources using accelerators in the medium energy region between 100 and 800 MeV. Measurements of the reaction products have been advanced by the continuous improvement in detector systems, electronics and computers. Corresponding developments in particle transport codes and in the theory of nuclear reactions at these energies have allowed more precise design of neutron sources, experimental shielding and detector response. As a result of these improvements, many new measurements are possible and themore » data base in this energy range is expanding quickly.« less

  17. Effects of Mode of Target Task Selection on Learning about Plants in a Mobile Learning Environment: Effortful Manual Selection versus Effortless QR-Code Selection

    ERIC Educational Resources Information Center

    Gao, Yuan; Liu, Tzu-Chien; Paas, Fred

    2016-01-01

    This study compared the effects of effortless selection of target plants using quick respond (QR) code technology to effortful manual search and selection of target plants on learning about plants in a mobile device supported learning environment. In addition, it was investigated whether the effectiveness of the 2 selection methods was…

  18. Boltzmann Transport Code Update: Parallelization and Integrated Design Updates

    NASA Technical Reports Server (NTRS)

    Heinbockel, J. H.; Nealy, J. E.; DeAngelis, G.; Feldman, G. A.; Chokshi, S.

    2003-01-01

    The on going efforts at developing a web site for radiation analysis is expected to result in an increased usage of the High Charge and Energy Transport Code HZETRN. It would be nice to be able to do the requested calculations quickly and efficiently. Therefore the question arose, "Could the implementation of parallel processing speed up the calculations required?" To answer this question two modifications of the HZETRN computer code were created. The first modification selected the shield material of Al(2219) , then polyethylene and then Al(2219). The modified Fortran code was labeled 1SSTRN.F. The second modification considered the shield material of CO2 and Martian regolith. This modified Fortran code was labeled MARSTRN.F.

  19. Converting Panax ginseng DNA and chemical fingerprints into two-dimensional barcode.

    PubMed

    Cai, Yong; Li, Peng; Li, Xi-Wen; Zhao, Jing; Chen, Hai; Yang, Qing; Hu, Hao

    2017-07-01

    In this study, we investigated how to convert the Panax ginseng DNA sequence code and chemical fingerprints into a two-dimensional code. In order to improve the compression efficiency, GATC2Bytes and digital merger compression algorithms are proposed. HPLC chemical fingerprint data of 10 groups of P. ginseng from Northeast China and the internal transcribed spacer 2 (ITS2) sequence code as the DNA sequence code were ready for conversion. In order to convert such data into a two-dimensional code, the following six steps were performed: First, the chemical fingerprint characteristic data sets were obtained through the inflection filtering algorithm. Second, precompression processing of such data sets is undertaken. Third, precompression processing was undertaken with the P. ginseng DNA (ITS2) sequence codes. Fourth, the precompressed chemical fingerprint data and the DNA (ITS2) sequence code were combined in accordance with the set data format. Such combined data can be compressed by Zlib, an open source data compression algorithm. Finally, the compressed data generated a two-dimensional code called a quick response code (QR code). Through the abovementioned converting process, it can be found that the number of bytes needed for storing P. ginseng chemical fingerprints and its DNA (ITS2) sequence code can be greatly reduced. After GTCA2Bytes algorithm processing, the ITS2 compression rate reaches 75% and the chemical fingerprint compression rate exceeds 99.65% via filtration and digital merger compression algorithm processing. Therefore, the overall compression ratio even exceeds 99.36%. The capacity of the formed QR code is around 0.5k, which can easily and successfully be read and identified by any smartphone. P. ginseng chemical fingerprints and its DNA (ITS2) sequence code can form a QR code after data processing, and therefore the QR code can be a perfect carrier of the authenticity and quality of P. ginseng information. This study provides a theoretical basis for the development of a quality traceability system of traditional Chinese medicine based on a two-dimensional code.

  20. Just in time? Using QR codes for multi-professional learning in clinical practice.

    PubMed

    Jamu, Joseph Tawanda; Lowi-Jones, Hannah; Mitchell, Colin

    2016-07-01

    Clinical guidelines and policies are widely available on the hospital intranet or from the internet, but can be difficult to access at the required time and place. Clinical staff with smartphones could use Quick Response (QR) codes for contemporaneous access to relevant information to support the Just in Time Learning (JIT-L) paradigm. There are several studies that advocate the use of smartphones to enhance learning amongst medical students and junior doctors in UK. However, these participants are already technologically orientated. There are limited studies that explore the use of smartphones in nursing practice. QR Codes were generated for each topic and positioned at relevant locations on a medical ward. Support and training were provided for staff. Website analytics and semi-structured interviews were performed to evaluate the efficacy, acceptability and feasibility of using QR codes to facilitate Just in Time learning. Use was intermittently high but not sustained. Thematic analysis of interviews revealed a positive assessment of the Just in Time learning paradigm and context-sensitive clinical information. However, there were notable barriers to acceptance, including usability of QR codes and appropriateness of smartphone use in a clinical environment. The use of Just in Time learning for education and reference may be beneficial to healthcare professionals. However, alternative methods of access for less technologically literate users and a change in culture of mobile device use in clinical areas may be needed. Copyright © 2016 Elsevier Ltd. All rights reserved.

  1. UCLA Final Technical Report for the "Community Petascale Project for Accelerator Science and Simulation”.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mori, Warren

    The UCLA Plasma Simulation Group is a major partner of the “Community Petascale Project for Accelerator Science and Simulation”. This is the final technical report. We include an overall summary, a list of publications, progress for the most recent year, and individual progress reports for each year. We have made tremendous progress during the three years. SciDAC funds have contributed to the development of a large number of skeleton codes that illustrate how to write PIC codes with a hierarchy of parallelism. These codes cover 2D and 3D as well as electrostatic solvers (which are used in beam dynamics codesmore » and quasi-static codes) and electromagnetic solvers (which are used in plasma based accelerator codes). We also used these ideas to develop a GPU enabled version of OSIRIS. SciDAC funds were also contributed to the development of strategies to eliminate the Numerical Cerenkov Instability (NCI) which is an issue when carrying laser wakefield accelerator (LWFA) simulations in a boosted frame and when quantifying the emittance and energy spread of self-injected electron beams. This work included the development of a new code called UPIC-EMMA which is an FFT based electromagnetic PIC code and to new hybrid algorithms in OSIRIS. A new hybrid (PIC in r-z and gridless in φ) algorithm was implemented into OSIRIS. In this algorithm the fields and current are expanded into azimuthal harmonics and the complex amplitude for each harmonic is calculated separately. The contributions from each harmonic are summed and then used to push the particles. This algorithm permits modeling plasma based acceleration with some 3D effects but with the computational load of an 2D r-z PIC code. We developed a rigorously charge conserving current deposit for this algorithm. Very recently, we made progress in combining the speed up from the quasi-3D algorithm with that from the Lorentz boosted frame. SciDAC funds also contributed to the improvement and speed up of the quasi-static PIC code QuickPIC. We have also used our suite of PIC codes to make scientific discovery. Highlights include supporting FACET experiments which achieved the milestones of showing high beam loading and energy transfer efficiency from a drive electron beam to a witness electron beam and the discovery of a self-loading regime a for high gradient acceleration of a positron beam. Both of these experimental milestones were published in Nature together with supporting QuickPIC simulation results. Simulation results from QuickPIC were used on the cover of Nature in one case. We are also making progress on using highly resolved QuickPIC simulations to show that ion motion may not lead to catastrophic emittance growth for tightly focused electron bunches loaded into nonlinear wakefields. This could mean that fully self-consistent beam loading scenarios are possible. This work remains in progress. OSIRIS simulations were used to discover how 200 MeV electron rings are formed in LWFA experiments, on how to generate electrons that have a series of bunches on nanometer scale, and how to transport electron beams from (into) plasma sections into (from) conventional beam optic sections.« less

  2. RELAP5-3D developmental assessment: Comparison of version 4.2.1i on Linux and Windows

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bayless, Paul D.

    2014-06-01

    Figures have been generated comparing the parameters used in the developmental assessment of the RELAP5-3D code, version 4.2i, compiled on Linux and Windows platforms. The figures, which are the same as those used in Volume III of the RELAP5-3D code manual, compare calculations using the semi-implicit solution scheme with available experiment data. These figures provide a quick, visual indication of how the code predictions differ between the Linux and Windows versions.

  3. RELAP5-3D Developmental Assessment. Comparison of Version 4.3.4i on Linux and Windows

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bayless, Paul David

    2015-10-01

    Figures have been generated comparing the parameters used in the developmental assessment of the RELAP5-3D code, version 4.3i, compiled on Linux and Windows platforms. The figures, which are the same as those used in Volume III of the RELAP5-3D code manual, compare calculations using the semi-implicit solution scheme with available experiment data. These figures provide a quick, visual indication of how the code predictions differ between the Linux and Windows versions.

  4. Towards a Framework for Generating Tests to Satisfy Complex Code Coverage in Java Pathfinder

    NASA Technical Reports Server (NTRS)

    Staats, Matt

    2009-01-01

    We present work on a prototype tool based on the JavaPathfinder (JPF) model checker for automatically generating tests satisfying the MC/DC code coverage criterion. Using the Eclipse IDE, developers and testers can quickly instrument Java source code with JPF annotations covering all MC/DC coverage obligations, and JPF can then be used to automatically generate tests that satisfy these obligations. The prototype extension to JPF enables various tasks useful in automatic test generation to be performed, such as test suite reduction and execution of generated tests.

  5. Evaluation of the efficiency and fault density of software generated by code generators

    NASA Technical Reports Server (NTRS)

    Schreur, Barbara

    1993-01-01

    Flight computers and flight software are used for GN&C (guidance, navigation, and control), engine controllers, and avionics during missions. The software development requires the generation of a considerable amount of code. The engineers who generate the code make mistakes and the generation of a large body of code with high reliability requires considerable time. Computer-aided software engineering (CASE) tools are available which generates code automatically with inputs through graphical interfaces. These tools are referred to as code generators. In theory, code generators could write highly reliable code quickly and inexpensively. The various code generators offer different levels of reliability checking. Some check only the finished product while some allow checking of individual modules and combined sets of modules as well. Considering NASA's requirement for reliability, an in house manually generated code is needed. Furthermore, automatically generated code is reputed to be as efficient as the best manually generated code when executed. In house verification is warranted.

  6. 3D assembly of upconverting NaYF4 nanocrystals by AFM nanoxerography: creation of anti-counterfeiting microtags

    NASA Astrophysics Data System (ADS)

    Sangeetha, Neralagatta M.; Moutet, Pierre; Lagarde, Delphine; Sallen, Gregory; Urbaszek, Bernhard; Marie, Xavier; Viau, Guillaume; Ressier, Laurence

    2013-09-01

    Formation of 3D close-packed assemblies of upconverting NaYF4 colloidal nanocrystals (NCs) on surfaces, by Atomic Force Microscopy (AFM) nanoxerography is presented. The surface potential of the charge patterns, the NC concentration, the polarizability of the NCs and the polarity of the dispersing solvent are identified as the key parameters controlling the assembly of NaYF4 NCs into micropatterns of the desired 3D architecture. This insight allowed us to fabricate micrometer sized Quick Response (QR) codes encoded in terms of upconversion luminescence intensity or color. Topographically hidden messages could also be readily incorporated within these microtags. This work demonstrates that AFM nanoxerography has enormous potential for generating high-security anti-counterfeiting microtags.Formation of 3D close-packed assemblies of upconverting NaYF4 colloidal nanocrystals (NCs) on surfaces, by Atomic Force Microscopy (AFM) nanoxerography is presented. The surface potential of the charge patterns, the NC concentration, the polarizability of the NCs and the polarity of the dispersing solvent are identified as the key parameters controlling the assembly of NaYF4 NCs into micropatterns of the desired 3D architecture. This insight allowed us to fabricate micrometer sized Quick Response (QR) codes encoded in terms of upconversion luminescence intensity or color. Topographically hidden messages could also be readily incorporated within these microtags. This work demonstrates that AFM nanoxerography has enormous potential for generating high-security anti-counterfeiting microtags. Electronic supplementary information (ESI) available: Detailed experimental procedures for the synthesis of upconverting NaYF4 nanocrystals and their transmission electron microscopy images. KFM and AFM images corresponding to the assembly of positively charged β-NaYF4:Er3+,Yb3+ nanocrystals from water suspensions by AFM nanoxerography. Photoluminescence spectra of β-NaYF4:Er3+,Yb3+ nanocrystals in a hexane suspension and assembled on charge patterns. See DOI: 10.1039/c3nr02734a

  7. Computer Aided Self-Forging Fragment Design,

    DTIC Science & Technology

    1978-06-01

    This value is reached so quickly that HEMP solutions using work hardening and those using only elastic—perfectly plastic formulations are quite...Elastic— Plastic Flow, UCRL—7322 , Lawrence Radiation Laboratory , Livermore , California (1969) . 4. Giroux , E. D . , HEMP Users Manual, UCRL—5l079...Laboratory, the HEMP computer code has been developed to serve as an effective design tool to simplify this task considerably. Using this code, warheads 78 06

  8. Genomics dataset on unclassified published organism (patent US 7547531).

    PubMed

    Khan Shawan, Mohammad Mahfuz Ali; Hasan, Md Ashraful; Hossain, Md Mozammel; Hasan, Md Mahmudul; Parvin, Afroza; Akter, Salina; Uddin, Kazi Rasel; Banik, Subrata; Morshed, Mahbubul; Rahman, Md Nazibur; Rahman, S M Badier

    2016-12-01

    Nucleotide (DNA) sequence analysis provides important clues regarding the characteristics and taxonomic position of an organism. With the intention that, DNA sequence analysis is very crucial to learn about hierarchical classification of that particular organism. This dataset (patent US 7547531) is chosen to simplify all the complex raw data buried in undisclosed DNA sequences which help to open doors for new collaborations. In this data, a total of 48 unidentified DNA sequences from patent US 7547531 were selected and their complete sequences were retrieved from NCBI BioSample database. Quick response (QR) code of those DNA sequences was constructed by DNA BarID tool. QR code is useful for the identification and comparison of isolates with other organisms. AT/GC content of the DNA sequences was determined using ENDMEMO GC Content Calculator, which indicates their stability at different temperature. The highest GC content was observed in GP445188 (62.5%) which was followed by GP445198 (61.8%) and GP445189 (59.44%), while lowest was in GP445178 (24.39%). In addition, New England BioLabs (NEB) database was used to identify cleavage code indicating the 5, 3 and blunt end and enzyme code indicating the methylation site of the DNA sequences was also shown. These data will be helpful for the construction of the organisms' hierarchical classification, determination of their phylogenetic and taxonomic position and revelation of their molecular characteristics.

  9. Sarcomere Length and Tension Changes in Tetanized Frog Muscle Fibers after Quick Stretches and Releases

    NASA Astrophysics Data System (ADS)

    Sugi, Haruo; Kobayashi, Takakazu

    1983-10-01

    The sarcomere length changes in tetanized frog muscle fibers in response to quick fiber length changes were examined along the fiber length with a high-sensitivity laser diffraction technique. The experiments were only performed with muscle fibers in which the uniform orientation and sarcomere length of the component myofibrils were well preserved during a tetanus. When the sarcomere length changes were recorded near the fixed fiber end, the delay of the onset of sarcomere length change in response to the applied fiber length change tended to be longer than that of the onset of tension changes recorded at the fixed fiber end. The magnitude of sarcomere length changes was larger near the moving fiber end than near the fixed fiber end. In the case of quick releases, the resulting sarcomere shortening tended to outlast the fiber shortening, so that the quick tension recovery started during the sarcomere shortening. These results indicate (i) that the tension changes in response to quick fiber length changes may not give direct information about the cross-bridge properties and (ii) that the viscoelastic multisegmental nature of muscle fibers should be taken into consideration in interpreting the tension responses to quick length changes.

  10. The development of a quick-running prediction tool for the assessment of human injury owing to terrorist attack within crowded metropolitan environments

    PubMed Central

    Pope, Daniel J.

    2011-01-01

    In the aftermath of the London ‘7/7’ attacks in 2005, UK government agencies required the development of a quick-running tool to predict the weapon and injury effects caused by the initiation of a person borne improvised explosive device (PBIED) within crowded metropolitan environments. This prediction tool, termed the HIP (human injury predictor) code, was intended to: — assist the security services to encourage favourable crowd distributions and densities within scenarios of ‘sensitivity’;— provide guidance to security engineers concerning the most effective location for protection systems;— inform rescue services as to where, in the case of such an event, individuals with particular injuries will be located;— assist in training medical personnel concerning the scope and types of injuries that would be sustained as a consequence of a particular attack;— assist response planners in determining the types of medical specialists (burns, traumatic amputations, lungs, etc.) required and thus identify the appropriate hospitals to receive the various casualty types.This document describes the algorithms used in the development of this tool, together with the pertinent underpinning physical processes. From its rudimentary beginnings as a simple spreadsheet, the HIP code now has a graphical user interface (GUI) that allows three-dimensional visualization of results and intuitive scenario set-up. The code is underpinned by algorithms that predict the pressure and momentum outputs produced by PBIEDs within open and confined environments, as well as the trajectories of shrapnel deliberately placed within the device to increase injurious effects. Further logic has been implemented to transpose these weapon effects into forms of human injury depending on where individuals are located relative to the PBIED. Each crowd member is subdivided into representative body parts, each of which is assigned an abbreviated injury score after a particular calculation cycle. The injury levels of each affected body part are then summated and a triage state assigned for each individual crowd member based on the criteria specified within the ‘injury scoring system’. To attain a comprehensive picture of a particular event, it is important that a number of simulations, using what is substantively the same scenario, are undertaken with natural variation being applied to the crowd distributions and the PBIED output. Accurate mathematical representation of such complex phenomena is challenging, particularly as the code must be quick-running to be of use to the stakeholder community. In addition to discussing the background and motivation for the algorithm and GUI development, this document also discusses the steps taken to validate the tool and the plans for further functionality implementation. PMID:21149351

  11. The development of a quick-running prediction tool for the assessment of human injury owing to terrorist attack within crowded metropolitan environments.

    PubMed

    Pope, Daniel J

    2011-01-27

    In the aftermath of the London '7/7' attacks in 2005, UK government agencies required the development of a quick-running tool to predict the weapon and injury effects caused by the initiation of a person borne improvised explosive device (PBIED) within crowded metropolitan environments. This prediction tool, termed the HIP (human injury predictor) code, was intended to:--assist the security services to encourage favourable crowd distributions and densities within scenarios of 'sensitivity'; --provide guidance to security engineers concerning the most effective location for protection systems; --inform rescue services as to where, in the case of such an event, individuals with particular injuries will be located; --assist in training medical personnel concerning the scope and types of injuries that would be sustained as a consequence of a particular attack; --assist response planners in determining the types of medical specialists (burns, traumatic amputations, lungs, etc.) required and thus identify the appropriate hospitals to receive the various casualty types. This document describes the algorithms used in the development of this tool, together with the pertinent underpinning physical processes. From its rudimentary beginnings as a simple spreadsheet, the HIP code now has a graphical user interface (GUI) that allows three-dimensional visualization of results and intuitive scenario set-up. The code is underpinned by algorithms that predict the pressure and momentum outputs produced by PBIEDs within open and confined environments, as well as the trajectories of shrapnel deliberately placed within the device to increase injurious effects. Further logic has been implemented to transpose these weapon effects into forms of human injury depending on where individuals are located relative to the PBIED. Each crowd member is subdivided into representative body parts, each of which is assigned an abbreviated injury score after a particular calculation cycle. The injury levels of each affected body part are then summated and a triage state assigned for each individual crowd member based on the criteria specified within the 'injury scoring system'. To attain a comprehensive picture of a particular event, it is important that a number of simulations, using what is substantively the same scenario, are undertaken with natural variation being applied to the crowd distributions and the PBIED output. Accurate mathematical representation of such complex phenomena is challenging, particularly as the code must be quick-running to be of use to the stakeholder community. In addition to discussing the background and motivation for the algorithm and GUI development, this document also discusses the steps taken to validate the tool and the plans for further functionality implementation.

  12. Image compression using quad-tree coding with morphological dilation

    NASA Astrophysics Data System (ADS)

    Wu, Jiaji; Jiang, Weiwei; Jiao, Licheng; Wang, Lei

    2007-11-01

    In this paper, we propose a new algorithm which integrates morphological dilation operation to quad-tree coding, the purpose of doing this is to compensate each other's drawback by using quad-tree coding and morphological dilation operation respectively. New algorithm can not only quickly find the seed significant coefficient of dilation but also break the limit of block boundary of quad-tree coding. We also make a full use of both within-subband and cross-subband correlation to avoid the expensive cost of representing insignificant coefficients. Experimental results show that our algorithm outperforms SPECK and SPIHT. Without using any arithmetic coding, our algorithm can achieve good performance with low computational cost and it's more suitable to mobile devices or scenarios with a strict real-time requirement.

  13. Reliability, Validity, and Responsiveness of the QuickDASH in Patients With Upper Limb Amputation.

    PubMed

    Resnik, Linda; Borgia, Matthew

    2015-09-01

    To examine the internal consistency, test-retest reliability, validity, and responsiveness of the shortened version of the Disabilities of the Arm, Shoulder and Hand (QuickDASH) questionnaire in persons with upper limb amputation. Cross-sectional and longitudinal. Three sites participating in the U.S. Department of Veterans Affairs Home Study of the DEKA Arm. A convenience sample of upper limb amputees (N=44). Training with a multifunction upper limb prosthesis. Multiple outcome measures including the QuickDASH were administered twice within 1 week, and for a subset of 20 persons, after completion of in-laboratory training with the DEKA Arm. Scale alphas and intraclass correlation coefficient type 3,1 (ICC3,1) were used to examine reliability. Minimum detectable change (MDC) scores were calculated. Analyses of variance, comparing QuickDASH scores by the amount of prosthetic use and amputation level, were used for known-group validity analyses with alpha set at .05. Pairwise correlations between QuickDASH and other measures were used to examine concurrent validity. Responsiveness was measured by effect size (ES) and standardized response mean (SRM). QuickDASH alpha was .83, and ICC was .87 (95% confidence interval, .77-.93). MDC at the 95% confidence level (MDC95%) was 17.4. Full- or part-time prosthesis users had better QuickDASH scores compared with nonprosthesis users (P=.021), as did those with more distal amputations at both baseline (P=.042) and with the DEKA Arm (P=.024). The QuickDASH was correlated with concurrent measures of activity limitation as expected. The ES and SRM after training with the DEKA Arm were 0.6. This study provides evidence of reliability and validity of the QuickDASH in persons with upper limb amputation. Results provide preliminary evidence of responsiveness to prosthetic device type/training. Further research with a larger sample is needed to confirm results. Copyright © 2015 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

  14. HSFs, Stress Sensors and Sculptors of Transcription Compartments and Epigenetic Landscapes.

    PubMed

    Miozzo, Federico; Sabéran-Djoneidi, Délara; Mezger, Valérie

    2015-12-04

    Starting as a paradigm for stress responses, the study of the transcription factor (TF) family of heat shock factors (HSFs) has quickly and widely expanded these last decades, thanks to their fascinating and significant involvement in a variety of pathophysiological processes, including development, reproduction, neurodegeneration and carcinogenesis. HSFs, originally defined as classical TFs, strikingly appeared to play a central and often pioneering role in reshaping the epigenetic landscape. In this review, we describe how HSFs are able to sense the epigenetic environment, and we review recent data that support their role as sculptors of the chromatin landscape through their complex interplay with chromatin remodelers, histone-modifying enzymes and non-coding RNAs. Copyright © 2015 Elsevier Ltd. All rights reserved.

  15. A comprehensive experimental characterization of the iPIX gamma imager

    NASA Astrophysics Data System (ADS)

    Amgarou, K.; Paradiso, V.; Patoz, A.; Bonnet, F.; Handley, J.; Couturier, P.; Becker, F.; Menaa, N.

    2016-08-01

    The results of more than 280 different experiments aimed at exploring the main features and performances of a newly developed gamma imager, called iPIX, are summarized in this paper. iPIX is designed to quickly localize radioactive sources while estimating the ambient dose equivalent rate at the measurement point. It integrates a 1 mm thick CdTe detector directly bump-bonded to a Timepix chip, a tungsten coded-aperture mask, and a mini RGB camera. It also represents a major technological breakthrough in terms of lightness, compactness, usability, response sensitivity, and angular resolution. As an example of its key strengths, an 241Am source with a dose rate of only few nSv/h can be localized in less than one minute.

  16. Lattice Calibration with Turn-By-Turn BPM Data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Huang, Xiaobiao; /SLAC; Sebek, James

    2012-07-02

    Turn-by-turn beam position monitor (BPM) data from multiple BPMs are fitted with a tracking code to calibrate magnet strengths in a manner similar to the well known LOCO code. Simulation shows that this turn-by-turn method can be a quick and efficient way for optics calibration. The method is applicable to both linacs and ring accelerators. Experimental results for a section of the SPEAR3 ring is also shown.

  17. High Performance Object-Oriented Scientific Programming in Fortran 90

    NASA Technical Reports Server (NTRS)

    Norton, Charles D.; Decyk, Viktor K.; Szymanski, Boleslaw K.

    1997-01-01

    We illustrate how Fortran 90 supports object-oriented concepts by example of plasma particle computations on the IBM SP. Our experience shows that Fortran 90 and object-oriented methodology give high performance while providing a bridge from Fortran 77 legacy codes to modern programming principles. All of our object-oriented Fortran 90 codes execute more quickly thatn the equeivalent C++ versions, yet the abstraction modelling capabilities used for scentific programming are comparably powereful.

  18. MOCCA code for star cluster simulation: comparison with optical observations using COCOA

    NASA Astrophysics Data System (ADS)

    Askar, Abbas; Giersz, Mirek; Pych, Wojciech; Olech, Arkadiusz; Hypki, Arkadiusz

    2016-02-01

    We introduce and present preliminary results from COCOA (Cluster simulatiOn Comparison with ObservAtions) code for a star cluster after 12 Gyr of evolution simulated using the MOCCA code. The COCOA code is being developed to quickly compare results of numerical simulations of star clusters with observational data. We use COCOA to obtain parameters of the projected cluster model. For comparison, a FITS file of the projected cluster was provided to observers so that they could use their observational methods and techniques to obtain cluster parameters. The results show that the similarity of cluster parameters obtained through numerical simulations and observations depends significantly on the quality of observational data and photometric accuracy.

  19. Role of cerebellar nodulus and uvula on the vestibular quick phase spatial constancy.

    PubMed

    Pettorossi, V E; Grassi, S; Errico, P; Barmack, N H

    2001-01-01

    We investigated the orientation of quick phases (QPs) of vestibularly-induced eye movements in rabbits in response to "off-vertical" sinusoidal vestibular stimulation. We also examined the possible role of the cerebellar nodulus and ventral uvula in controlling QP spatial orientation and modification. During "off-vertical" vestibular stimulation QPs remained aligned with the earth's horizontal plane, while the slow phases (SPs) were aligned with the plane of vestibular stimulation. This suggests that QPs are coded in gravito-inertial coordinates and SPs in head coordinates. When rabbits were oscillated in the light (20 degrees peak-to-peak; 0.2 Hz) about an "off-vertical" axis for 2 h, the QPs changed their trajectory, abandoning the earth's horizontal plane to approach the plane of the stimulus. By contrast, in the absence of conjunctive optokinetic stimulation, QPs remained fixed in the earth's horizontal plane even after 2 h of "off-vertical" stimulation. The conjunctive combination of optokinetic and vestibular stimulation caused QPs to change their plane of rotation. After lesion of the nodulus-uvula the ability of rabbits to reorient QPs during conjoint vestibular-optokinetic stimulation was maintained. We conclude that the space orientation and adaptation of QPs do not require cerebellar control.

  20. Architecture of the parallel hierarchical network for fast image recognition

    NASA Astrophysics Data System (ADS)

    Timchenko, Leonid; Wójcik, Waldemar; Kokriatskaia, Natalia; Kutaev, Yuriy; Ivasyuk, Igor; Kotyra, Andrzej; Smailova, Saule

    2016-09-01

    Multistage integration of visual information in the brain allows humans to respond quickly to most significant stimuli while maintaining their ability to recognize small details in the image. Implementation of this principle in technical systems can lead to more efficient processing procedures. The multistage approach to image processing includes main types of cortical multistage convergence. The input images are mapped into a flexible hierarchy that reflects complexity of image data. Procedures of the temporal image decomposition and hierarchy formation are described in mathematical expressions. The multistage system highlights spatial regularities, which are passed through a number of transformational levels to generate a coded representation of the image that encapsulates a structure on different hierarchical levels in the image. At each processing stage a single output result is computed to allow a quick response of the system. The result is presented as an activity pattern, which can be compared with previously computed patterns on the basis of the closest match. With regard to the forecasting method, its idea lies in the following. In the results synchronization block, network-processed data arrive to the database where a sample of most correlated data is drawn using service parameters of the parallel-hierarchical network.

  1. Analytic programming with FMRI data: a quick-start guide for statisticians using R.

    PubMed

    Eloyan, Ani; Li, Shanshan; Muschelli, John; Pekar, Jim J; Mostofsky, Stewart H; Caffo, Brian S

    2014-01-01

    Functional magnetic resonance imaging (fMRI) is a thriving field that plays an important role in medical imaging analysis, biological and neuroscience research and practice. This manuscript gives a didactic introduction to the statistical analysis of fMRI data using the R project, along with the relevant R code. The goal is to give statisticians who would like to pursue research in this area a quick tutorial for programming with fMRI data. References of relevant packages and papers are provided for those interested in more advanced analysis.

  2. Estimation of the biphasic property in a female's menstrual cycle from cutaneous temperature measured during sleep.

    PubMed

    Chen, Wenxi; Kitazawa, Masumi; Togawa, Tatsuo

    2009-09-01

    This paper proposes a method to estimate a woman's menstrual cycle based on the hidden Markov model (HMM). A tiny device was developed that attaches around the abdominal region to measure cutaneous temperature at 10-min intervals during sleep. The measured temperature data were encoded as a two-dimensional image (QR code, i.e., quick response code) and displayed in the LCD window of the device. A mobile phone captured the QR code image, decoded the information and transmitted the data to a database server. The collected data were analyzed by three steps to estimate the biphasic temperature property in a menstrual cycle. The key step was an HMM-based step between preprocessing and postprocessing. A discrete Markov model, with two hidden phases, was assumed to represent higher- and lower-temperature phases during a menstrual cycle. The proposed method was verified by the data collected from 30 female participants, aged from 14 to 46, over six consecutive months. By comparing the estimated results with individual records from the participants, 71.6% of 190 menstrual cycles were correctly estimated. The sensitivity and positive predictability were 91.8 and 96.6%, respectively. This objective evaluation provides a promising approach for managing premenstrual syndrome and birth control.

  3. RELAP5-3D Developmental Assessment: Comparison of Versions 4.3.4i and 4.2.1i

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bayless, Paul David

    2015-10-01

    Figures have been generated comparing the parameters used in the developmental assessment of the RELAP5-3D code using versions 4.3.4i and 4.2.1i. The figures, which are the same as those used in Volume III of the RELAP5-3D code manual, compare calculations using the semi-implicit solution scheme with available experiment data. These figures provide a quick, visual indication of how the code predictions changed between these two code versions and can be used to identify cases in which the assessment judgment may need to be changed in Volume III of the code manual. Changes to the assessment judgments made after reviewing allmore » of the assessment cases are also provided.« less

  4. RELAP5-3D Developmental Assessment: Comparison of Versions 4.2.1i and 4.1.3i

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bayless, Paul D.

    2014-06-01

    Figures have been generated comparing the parameters used in the developmental assessment of the RELAP5-3D code using versions 4.2.1i and 4.1.3i. The figures, which are the same as those used in Volume III of the RELAP5-3D code manual, compare calculations using the semi-implicit solution scheme with available experiment data. These figures provide a quick, visual indication of how the code predictions changed between these two code versions and can be used to identify cases in which the assessment judgment may need to be changed in Volume III of the code manual. Changes to the assessment judgments made after reviewing allmore » of the assessment cases are also provided.« less

  5. Fast Computation of the Two-Point Correlation Function in the Age of Big Data

    NASA Astrophysics Data System (ADS)

    Pellegrino, Andrew; Timlin, John

    2018-01-01

    We present a new code which quickly computes the two-point correlation function for large sets of astronomical data. This code combines the ease of use of Python with the speed of parallel shared libraries written in C. We include the capability to compute the auto- and cross-correlation statistics, and allow the user to calculate the three-dimensional and angular correlation functions. Additionally, the code automatically divides the user-provided sky masks into contiguous subsamples of similar size, using the HEALPix pixelization scheme, for the purpose of resampling. Errors are computed using jackknife and bootstrap resampling in a way that adds negligible extra runtime, even with many subsamples. We demonstrate comparable speed with other clustering codes, and code accuracy compared to known and analytic results.

  6. User input verification and test driven development in the NJOY21 nuclear data processing code

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Trainer, Amelia Jo; Conlin, Jeremy Lloyd; McCartney, Austin Paul

    Before physically-meaningful data can be used in nuclear simulation codes, the data must be interpreted and manipulated by a nuclear data processing code so as to extract the relevant quantities (e.g. cross sections and angular distributions). Perhaps the most popular and widely-trusted of these processing codes is NJOY, which has been developed and improved over the course of 10 major releases since its creation at Los Alamos National Laboratory in the mid-1970’s. The current phase of NJOY development is the creation of NJOY21, which will be a vast improvement from its predecessor, NJOY2016. Designed to be fast, intuitive, accessible, andmore » capable of handling both established and modern formats of nuclear data, NJOY21 will address many issues that many NJOY users face, while remaining functional for those who prefer the existing format. Although early in its development, NJOY21 is quickly providing input validation to check user input. By providing rapid and helpful responses to users while writing input files, NJOY21 will prove to be more intuitive and easy to use than any of its predecessors. Furthermore, during its development, NJOY21 is subject to regular testing, such that its test coverage must strictly increase with the addition of any production code. This thorough testing will allow developers and NJOY users to establish confidence in NJOY21 as it gains functionality. This document serves as a discussion regarding the current state input checking and testing practices of NJOY21.« less

  7. A QR Code Based Zero-Watermarking Scheme for Authentication of Medical Images in Teleradiology Cloud

    PubMed Central

    Seenivasagam, V.; Velumani, R.

    2013-01-01

    Healthcare institutions adapt cloud based archiving of medical images and patient records to share them efficiently. Controlled access to these records and authentication of images must be enforced to mitigate fraudulent activities and medical errors. This paper presents a zero-watermarking scheme implemented in the composite Contourlet Transform (CT)—Singular Value Decomposition (SVD) domain for unambiguous authentication of medical images. Further, a framework is proposed for accessing patient records based on the watermarking scheme. The patient identification details and a link to patient data encoded into a Quick Response (QR) code serves as the watermark. In the proposed scheme, the medical image is not subjected to degradations due to watermarking. Patient authentication and authorized access to patient data are realized on combining a Secret Share with the Master Share constructed from invariant features of the medical image. The Hu's invariant image moments are exploited in creating the Master Share. The proposed system is evaluated with Checkmark software and is found to be robust to both geometric and non geometric attacks. PMID:23970943

  8. A QR code based zero-watermarking scheme for authentication of medical images in teleradiology cloud.

    PubMed

    Seenivasagam, V; Velumani, R

    2013-01-01

    Healthcare institutions adapt cloud based archiving of medical images and patient records to share them efficiently. Controlled access to these records and authentication of images must be enforced to mitigate fraudulent activities and medical errors. This paper presents a zero-watermarking scheme implemented in the composite Contourlet Transform (CT)-Singular Value Decomposition (SVD) domain for unambiguous authentication of medical images. Further, a framework is proposed for accessing patient records based on the watermarking scheme. The patient identification details and a link to patient data encoded into a Quick Response (QR) code serves as the watermark. In the proposed scheme, the medical image is not subjected to degradations due to watermarking. Patient authentication and authorized access to patient data are realized on combining a Secret Share with the Master Share constructed from invariant features of the medical image. The Hu's invariant image moments are exploited in creating the Master Share. The proposed system is evaluated with Checkmark software and is found to be robust to both geometric and non geometric attacks.

  9. DNA fingerprinting of Chinese melon provides evidentiary support of seed quality appraisal.

    PubMed

    Gao, Peng; Ma, Hongyan; Luan, Feishi; Song, Haibin

    2012-01-01

    Melon, Cucumis melo L. is an important vegetable crop worldwide. At present, there are phenomena of homonyms and synonyms present in the melon seed markets of China, which could cause variety authenticity issues influencing the process of melon breeding, production, marketing and other aspects. Molecular markers, especially microsatellites or simple sequence repeats (SSRs) are playing increasingly important roles for cultivar identification. The aim of this study was to construct a DNA fingerprinting database of major melon cultivars, which could provide a possibility for the establishment of a technical standard system for purity and authenticity identification of melon seeds. In this study, to develop the core set SSR markers, 470 polymorphic SSRs were selected as the candidate markers from 1219 SSRs using 20 representative melon varieties (lines). Eighteen SSR markers, evenly distributed across the genome and with the highest contents of polymorphism information (PIC) were identified as the core marker set for melon DNA fingerprinting analysis. Fingerprint codes for 471 melon varieties (lines) were established. There were 51 materials which were classified into17 groups based on sharing the same fingerprint code, while field traits survey results showed that these plants in the same group were synonyms because of the same or similar field characters. Furthermore, DNA fingerprinting quick response (QR) codes of 471 melon varieties (lines) were constructed. Due to its fast readability and large storage capacity, QR coding melon DNA fingerprinting is in favor of read convenience and commercial applications.

  10. DNA Fingerprinting of Chinese Melon Provides Evidentiary Support of Seed Quality Appraisal

    PubMed Central

    Gao, Peng; Ma, Hongyan; Luan, Feishi; Song, Haibin

    2012-01-01

    Melon, Cucumis melo L. is an important vegetable crop worldwide. At present, there are phenomena of homonyms and synonyms present in the melon seed markets of China, which could cause variety authenticity issues influencing the process of melon breeding, production, marketing and other aspects. Molecular markers, especially microsatellites or simple sequence repeats (SSRs) are playing increasingly important roles for cultivar identification. The aim of this study was to construct a DNA fingerprinting database of major melon cultivars, which could provide a possibility for the establishment of a technical standard system for purity and authenticity identification of melon seeds. In this study, to develop the core set SSR markers, 470 polymorphic SSRs were selected as the candidate markers from 1219 SSRs using 20 representative melon varieties (lines). Eighteen SSR markers, evenly distributed across the genome and with the highest contents of polymorphism information (PIC) were identified as the core marker set for melon DNA fingerprinting analysis. Fingerprint codes for 471 melon varieties (lines) were established. There were 51 materials which were classified into17 groups based on sharing the same fingerprint code, while field traits survey results showed that these plants in the same group were synonyms because of the same or similar field characters. Furthermore, DNA fingerprinting quick response (QR) codes of 471 melon varieties (lines) were constructed. Due to its fast readability and large storage capacity, QR coding melon DNA fingerprinting is in favor of read convenience and commercial applications. PMID:23285039

  11. Ionospheric Correction Based on Ingestion of Global Ionospheric Maps into the NeQuick 2 Model

    PubMed Central

    Yu, Xiao; She, Chengli; Zhen, Weimin; Bruno, Nava; Liu, Dun; Yue, Xinan; Ou, Ming; Xu, Jisheng

    2015-01-01

    The global ionospheric maps (GIMs), generated by Jet Propulsion Laboratory (JPL) and Center for Orbit Determination in Europe (CODE) during a period over 13 years, have been adopted as the primary source of data to provide global ionospheric correction for possible single frequency positioning applications. The investigation aims to assess the performance of new NeQuick model, NeQuick 2, in predicting global total electron content (TEC) through ingesting the GIMs data from the previous day(s). The results show good performance of the GIMs-driven-NeQuick model with average 86% of vertical TEC error less than 10 TECU, when the global daily effective ionization indices (Az) versus modified dip latitude (MODIP) are constructed as a second order polynomial. The performance of GIMs-driven-NeQuick model presents variability with solar activity and behaves better during low solar activity years. The accuracy of TEC prediction can be improved further through performing a four-coefficient function expression of Az versus MODIP. As more measurements from earlier days are involved in the Az optimization procedure, the accuracy may decrease. The results also reveal that more efforts are needed to improve the NeQuick 2 model capabilities to represent the ionosphere in the equatorial and high-latitude regions. PMID:25815369

  12. The Geology of Guadalcanal: A Selected Bibliography of the Geology, Natural History, and the History of Guadalcanal

    DTIC Science & Technology

    2007-09-01

    Guinea. But critics say that the code will be useless unless island governments back it up with laws that can be enforced. "The code is a quick fix, not a...water are privately described as "unworkable" and "mad". Critics see them as a smoke screen designed to divert attention from a disastrous logging...Walter Creighton. 1969. A New Frog of the Genus Discodeles (Ranidae) from Guadalcanal Island. Cambridge, Mass .: Museum of Comparative Zoology

  13. Method for computing self-consistent solution in a gun code

    DOEpatents

    Nelson, Eric M

    2014-09-23

    Complex gun code computations can be made to converge more quickly based on a selection of one or more relaxation parameters. An eigenvalue analysis is applied to error residuals to identify two error eigenvalues that are associated with respective error residuals. Relaxation values can be selected based on these eigenvalues so that error residuals associated with each can be alternately reduced in successive iterations. In some examples, relaxation values that would be unstable if used alone can be used.

  14. IEEE International Symposium on Information Theory (ISIT): Abstracts of Papers, Held in Ann Arbor, Michigan on 6-9 October 1986.

    DTIC Science & Technology

    1986-10-01

    BUZO, and FEDERICO KUHLMANN, Universidad Nacional Autdnoma de Mixico, Facultad de Ingenieria , Divisidn Estudios de Posgrado, P.O. Box 70-256, 04510...unsuccess- ful in this area for a long time. It was felt, e.g., in the voiceband modem industry , that the coding gains achievable by error-correction coding...without bandwidth expansion or data rate reduction, when compared to uncoded modulation. The concept was quickly adopted by industry , and is now becoming

  15. Modular Track System For Positioning Mobile Robots

    NASA Technical Reports Server (NTRS)

    Miller, Jeff

    1995-01-01

    Conceptual system for positioning mobile robotic manipulators on large main structure includes modular tracks and ancillary structures assembled easily along with main structure. System, called "tracked robotic location system" (TROLS), originally intended for application to platforms in outer space, but TROLS concept might also prove useful on Earth; for example, to position robots in factories and warehouses. T-cross-section rail keeps mobile robot on track. Bar codes mark locations along track. Each robot equipped with bar-code-recognizing circuitry so it quickly finds way to assigned location.

  16. A diagnostic for quantifying heat flux from a thermite spray

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    E. P. Nixon; M. L. Pantoya; D. J. Prentice

    2010-02-01

    Characterizing the combustion behaviors of energetic materials requires diagnostic tools that are often not readily or commercially available. For example, a jet of thermite spray provides a high temperature and pressure reaction that can also be highly corrosive and promote undesirable conditions for the survivability of any sensor. Developing a diagnostic to quantify heat flux from a thermite spray is the objective of this study. Quick response sensors such as thin film heat flux sensors cannot survive the harsh conditions of the spray, but more rugged sensors lack the response time for the resolution desired. A sensor that will allowmore » for adequate response time while surviving the entire test duration was constructed. The sensor outputs interior temperatures of the probes at known locations and utilizes an inverse heat conduction code to calculate heat flux values. The details of this device are discussed and illustrated. Temperature and heat flux measurements of various thermite sprays are reported. Results indicate that this newly designed heat flux sensor provides quantitative data with good repeatability suitable for characterizing energetic material combustion.« less

  17. QUANTIFICATION OF HEAT FLUX FROM A REACTING THERMITE SPRAY

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Eric Nixon; Michelle Pantoya

    2009-07-01

    Characterizing the combustion behaviors of energetic materials requires diagnostic tools that are often not readily or commercially available. For example, a jet of thermite spray provides a high temperature and pressure reaction that can also be highly corrosive and promote undesirable conditions for the survivability of any sensor. Developing a diagnostic to quantify heat flux from a thermite spray is the objective of this study. Quick response sensors such as thin film heat flux sensors can not survive the harsh conditions of the spray, but more rugged sensors lack the response time for the resolution desired. A sensor that willmore » allow for adequate response time while surviving the entire test duration was constructed. The sensor outputs interior temperatures of the probes at known locations and utilizes an inverse heat conduction code to calculate heat flux values. The details of this device are discussed and illustrated. Temperature and heat flux measurements of various thermite spray conditions are reported. Results indicate that this newly developed energetic material heat flux sensor provides quantitative data with good repeatability.« less

  18. Sonic Boom.

    ERIC Educational Resources Information Center

    Hurtig, Brent

    1998-01-01

    Reviews and evaluates Pro Tools 4.1, a multitrack digital audio workstation (DAWs) that imports and synchronizes to QuickTime or AVI digital movies. Audio-for-picture editors lock their digital audio workstations to linear videotape recorders, using complex, expensive time code synchronizers. Highlights Macintosh and Windows based alternatives.…

  19. Towards a numerical run-out model for quick-clay slides

    NASA Astrophysics Data System (ADS)

    Issler, Dieter; L'Heureux, Jean-Sébastien; Cepeda, José M.; Luna, Byron Quan; Gebreslassie, Tesfahunegn A.

    2015-04-01

    Highly sensitive glacio-marine clays occur in many relatively low-lying areas near the coasts of eastern Canada, Scandinavia and northern Russia. If the load exceeds the yield stress of these clays, they quickly liquefy, with a reduction of the yield strength and the viscosity by several orders of magnitude. Leaching, fluvial erosion, earthquakes and man-made overloads, by themselves or combined, are the most frequent triggers of quick-clay slides, which are hard to predict and can attain catastrophic dimensions. The present contribution reports on two preparatory studies that were conducted with a view to creating a run-out model tailored to the characteristics of quick-clay slides. One study analyzed the connections between the morphological and geotechnical properties of more than 30 well-documented Norwegian quick-clay slides and their run-out behavior. The laboratory experiments by Locat and Demers (1988) suggest that the behavior of quick clays can be reasonably described by universal relations involving the liquidity index, plastic index, remolding energy, salinity and sensitivity. However, these tests should be repeated with Norwegian clays and analyzed in terms of a (shear-thinning) Herschel-Bulkley fluid rather than a Bingham fluid because the shear stress appears to grow in a sub-linear fashion with the shear rate. Further study is required to understand the discrepancy between the material parameters obtained in laboratory tests of material from observed slides and in back-calculations of the same slides with the simple model by Edgers & Karlsrud (1982). The second study assessed the capability of existing numerical flow models to capture the most important aspects of quick-clay slides by back-calculating three different, well documented events in Norway: Rissa (1978), Finneidfjord (1996) and Byneset (2012). The numerical codes were (i) BING, a quasi-two-dimensional visco-plastic model, (ii) DAN3D (2009 version), and (iii) MassMov2D. The latter two are quasi-three-dimensional codes with a choice of bed-friction laws. The findings of the simulations point strongly towards the need for a different modeling approach that incorporates the essential physical features of quick-clay slides. The major requirement is a realistic description of remolding. A two-layer model is needed to describe the non-sensitive topsoil that often is passively advected by the slide. In many cases, the topography is rather complex so that 3D or quasi-3D (depth-averaged) models are required for realistic modeling of flow heights and velocities. Finally, since many Norwegian quick-clay slides run-out in a fjord (and may generate a tsunami), it is also desirable to explicitly account for buoyancy and hydrodynamic drag.

  20. A SNP panel and online tool for checking genotype concordance through comparing QR codes.

    PubMed

    Du, Yonghong; Martin, Joshua S; McGee, John; Yang, Yuchen; Liu, Eric Yi; Sun, Yingrui; Geihs, Matthias; Kong, Xuejun; Zhou, Eric Lingfeng; Li, Yun; Huang, Jie

    2017-01-01

    In the current precision medicine era, more and more samples get genotyped and sequenced. Both researchers and commercial companies expend significant time and resources to reduce the error rate. However, it has been reported that there is a sample mix-up rate of between 0.1% and 1%, not to mention the possibly higher mix-up rate during the down-stream genetic reporting processes. Even on the low end of this estimate, this translates to a significant number of mislabeled samples, especially over the projected one billion people that will be sequenced within the next decade. Here, we first describe a method to identify a small set of Single nucleotide polymorphisms (SNPs) that can uniquely identify a personal genome, which utilizes allele frequencies of five major continental populations reported in the 1000 genomes project and the ExAC Consortium. To make this panel more informative, we added four SNPs that are commonly used to predict ABO blood type, and another two SNPs that are capable of predicting sex. We then implement a web interface (http://qrcme.tech), nicknamed QRC (for QR code based Concordance check), which is capable of extracting the relevant ID SNPs from a raw genetic data, coding its genotype as a quick response (QR) code, and comparing QR codes to report the concordance of underlying genetic datasets. The resulting 80 fingerprinting SNPs represent a significant decrease in complexity and the number of markers used for genetic data labelling and tracking. Our method and web tool is easily accessible to both researchers and the general public who consider the accuracy of complex genetic data as a prerequisite towards precision medicine.

  1. A SNP panel and online tool for checking genotype concordance through comparing QR codes

    PubMed Central

    Du, Yonghong; Martin, Joshua S.; McGee, John; Yang, Yuchen; Liu, Eric Yi; Sun, Yingrui; Geihs, Matthias; Kong, Xuejun; Zhou, Eric Lingfeng; Li, Yun

    2017-01-01

    In the current precision medicine era, more and more samples get genotyped and sequenced. Both researchers and commercial companies expend significant time and resources to reduce the error rate. However, it has been reported that there is a sample mix-up rate of between 0.1% and 1%, not to mention the possibly higher mix-up rate during the down-stream genetic reporting processes. Even on the low end of this estimate, this translates to a significant number of mislabeled samples, especially over the projected one billion people that will be sequenced within the next decade. Here, we first describe a method to identify a small set of Single nucleotide polymorphisms (SNPs) that can uniquely identify a personal genome, which utilizes allele frequencies of five major continental populations reported in the 1000 genomes project and the ExAC Consortium. To make this panel more informative, we added four SNPs that are commonly used to predict ABO blood type, and another two SNPs that are capable of predicting sex. We then implement a web interface (http://qrcme.tech), nicknamed QRC (for QR code based Concordance check), which is capable of extracting the relevant ID SNPs from a raw genetic data, coding its genotype as a quick response (QR) code, and comparing QR codes to report the concordance of underlying genetic datasets. The resulting 80 fingerprinting SNPs represent a significant decrease in complexity and the number of markers used for genetic data labelling and tracking. Our method and web tool is easily accessible to both researchers and the general public who consider the accuracy of complex genetic data as a prerequisite towards precision medicine. PMID:28926565

  2. QUICK - AN INTERACTIVE SOFTWARE ENVIRONMENT FOR ENGINEERING DESIGN

    NASA Technical Reports Server (NTRS)

    Schlaifer, R. S.

    1994-01-01

    QUICK provides the computer user with the facilities of a sophisticated desk calculator which can perform scalar, vector and matrix arithmetic, propagate conic orbits, determine planetary and satellite coordinates and perform other related astrodynamic calculations within a Fortran-like environment. QUICK is an interpreter, therefore eliminating the need to use a compiler or a linker to run QUICK code. QUICK capabilities include options for automated printing of results, the ability to submit operating system commands on some systems, and access to a plotting package (MASL)and a text editor without leaving QUICK. Mathematical and programming features of QUICK include the ability to handle arbitrary algebraic expressions, the capability to define user functions in terms of other functions, built-in constants such as pi, direct access to useful COMMON areas, matrix capabilities, extensive use of double precision calculations, and the ability to automatically load user functions from a standard library. The MASL (The Multi-mission Analysis Software Library) plotting package, included in the QUICK package, is a set of FORTRAN 77 compatible subroutines designed to facilitate the plotting of engineering data by allowing programmers to write plotting device independent applications. Its universality lies in the number of plotting devices it puts at the user's disposal. The MASL package of routines has proved very useful and easy to work with, yielding good plots for most new users on the first or second try. The functions provided include routines for creating histograms, "wire mesh" surface plots and contour plots as well as normal graphs with a large variety of axis types. The library has routines for plotting on cartesian, polar, log, mercator, cyclic, calendar, and stereographic axes, and for performing automatic or explicit scaling. The lengths of the axes of a plot are completely under the control of the program using the library. Programs written to use the MASL subroutines can be made to output to the Calcomp 1055 plotter, the Hewlett-Packard 2648 graphics terminal, the HP 7221, 7475 and 7550 pen plotters, the Tektronix 40xx and 41xx series graphics terminals, the DEC VT125/VT240 graphics terminals, the QMS 800 laser printer, the Sun Microsystems monochrome display, the Ridge Computers monochrome display, the IBM/PC color display, or a "dumb" terminal or printer. Programs using this library can be written so that they always use the same type of plotter or they can allow the choice of plotter type to be deferred until after program execution. QUICK is written in RATFOR for use on Sun4 series computers running SunOS. No source code is provided. The standard distribution medium for this program is a .25 inch streaming magnetic tape cartridge in UNIX tar format. An electronic copy of the documentation in ASCII format is included on the distribution medium. QUICK was developed in 1991 and is a copyrighted work with all copyright vested in NASA.

  3. ULFEM time series analysis package

    USGS Publications Warehouse

    Karl, Susan M.; McPhee, Darcy K.; Glen, Jonathan M. G.; Klemperer, Simon L.

    2013-01-01

    This manual describes how to use the Ultra-Low-Frequency ElectroMagnetic (ULFEM) software package. Casual users can read the quick-start guide and will probably not need any more information than this. For users who may wish to modify the code, we provide further description of the routines.

  4. High fidelity 3-dimensional models of beam-electron cloud interactions in circular accelerators

    NASA Astrophysics Data System (ADS)

    Feiz Zarrin Ghalam, Ali

    Electron cloud is a low-density electron profile created inside the vacuum chamber of circular machines with positively charged beams. Electron cloud limits the peak current of the beam and degrades the beams' quality through luminosity degradation, emittance growth and head to tail or bunch to bunch instability. The adverse effects of electron cloud on long-term beam dynamics becomes more and more important as the beams go to higher and higher energies. This problem has become a major concern in many future circular machines design like the Large Hadron Collider (LHC) under construction at European Center for Nuclear Research (CERN). Due to the importance of the problem several simulation models have been developed to model long-term beam-electron cloud interaction. These models are based on "single kick approximation" where the electron cloud is assumed to be concentrated at one thin slab around the ring. While this model is efficient in terms of computational costs, it does not reflect the real physical situation as the forces from electron cloud to the beam are non-linear contrary to this model's assumption. To address the existing codes limitation, in this thesis a new model is developed to continuously model the beam-electron cloud interaction. The code is derived from a 3-D parallel Particle-In-Cell (PIC) model (QuickPIC) originally used for plasma wakefield acceleration research. To make the original model fit into circular machines environment, betatron and synchrotron equations of motions have been added to the code, also the effect of chromaticity, lattice structure have been included. QuickPIC is then benchmarked against one of the codes developed based on single kick approximation (HEAD-TAIL) for the transverse spot size of the beam in CERN-LHC. The growth predicted by QuickPIC is less than the one predicted by HEAD-TAIL. The code is then used to investigate the effect of electron cloud image charges on the long-term beam dynamics, particularly on the transverse tune shift of the beam at CERN Super Proton Synchrotron (SPS) ring. The force from the electron cloud image charges on the beam cancels the force due to cloud compression formed on the beam axis and therefore the tune shift is mainly due to the uniform electron cloud density. (Abstract shortened by UMI.)

  5. Tools and techniques for estimating high intensity RF effects

    NASA Astrophysics Data System (ADS)

    Zacharias, Richard L.; Pennock, Steve T.; Poggio, Andrew J.; Ray, Scott L.

    1992-01-01

    Tools and techniques for estimating and measuring coupling and component disturbance for avionics and electronic controls are described. A finite-difference-time-domain (FD-TD) modeling code, TSAR, used to predict coupling is described. This code can quickly generate a mesh model to represent the test object. Some recent applications as well as the advantages and limitations of using such a code are described. Facilities and techniques for making low-power coupling measurements and for making direct injection test measurements of device disturbance are also described. Some scaling laws for coupling and device effects are presented. A method for extrapolating these low-power test results to high-power full-system effects are presented.

  6. A non-verbal technique for the assessment of general intellectual ability in selection of aviation personnel.

    DOT National Transportation Integrated Search

    1971-06-01

    A study was conducted in which performance on a non-verbal problem- solving task was correlated with the Otis Quick Scoring Mental Ability Test and the Raven Progressive Matrices Test. The problem-solving task, called 'code- lock' required the subjec...

  7. Language Simulations: The Blending Space for Writing and Critical Thinking

    ERIC Educational Resources Information Center

    Kovalik, Doina L.; Kovalik, Ludovic M.

    2007-01-01

    This article describes a language simulation involving six distinct phases: an in-class quick response, a card game, individual research, a classroom debate, a debriefing session, and an argumentative essay. An analysis of student artifacts--quick-response writings and final essays, respectively, both addressing the definition of liberty in a…

  8. CFD analysis of jet mixing in low NOx flametube combustors

    NASA Technical Reports Server (NTRS)

    Talpallikar, M. V.; Smith, C. E.; Lai, M. C.; Holdeman, J. D.

    1991-01-01

    The Rich-burn/Quick-mix/Lean-burn (RQL) combustor was identified as a potential gas turbine combustor concept to reduce NO(x) emissions in High Speed Civil Transport (HSCT) aircraft. To demonstrate reduced NO(x) levels, cylindrical flametube versions of RQL combustors are being tested at NASA Lewis Research Center. A critical technology needed for the RQL combustor is a method of quickly mixing by-pass combustion air with rich-burn gases. Jet mixing in a cylindrical quick-mix section was numerically analyzed. The quick-mix configuration was five inches in diameter and employed twelve radial-inflow slots. The numerical analyses were performed with an advanced, validated 3-D Computational Fluid Dynamics (CFD) code named REFLEQS. Parametric variation of jet-to-mainstream momentum flux ratio (J) and slot aspect ratio was investigated. Both non-reacting and reacting analyses were performed. Results showed mixing and NO(x) emissions to be highly sensitive to J and slot aspect ratio. Lowest NO(x) emissions occurred when the dilution jet penetrated to approximately mid-radius. The viability of using 3-D CFD analyses for optimizing jet mixing was demonstrated.

  9. CFD analysis of jet mixing in low NO(x) flametube combustors

    NASA Technical Reports Server (NTRS)

    Talpallikar, M. V.; Smith, C. E.; Lai, M. C.; Holdeman, J. D.

    1991-01-01

    The Rich-burn/Quick-mix/Lean-burn (RQL) combustor has been identified as a potential gas turbine combustor concept to reduce NO(x) emissions in High Speed Civil Transport (HSCT) aircraft. To demonstrate reduced NO(x) levels, cylindrical flametube versions of RQL combustors are being tested at NASA Lewis Research Center. A critical technology needed for the RQL combustor is a method of quickly mixing by-pass combustion air with rich-burn gases. Jet mixing in a cylindrical quick-mix section was numerically analyzed. The quick-mix configuration was five inches in diameter and employed twelve radial-inflow slots. The numerical analyses were performed with an advanced, validated 3D Computational Fluid Dynamics (CFD) code named REFLEQS. Parametric variation of jet-to-mainstream momentum flux ratio (J) and slot aspect ratio was investigated. Both non-reacting and reacting analyses were performed. Results showed mixing and NO(x) emissions to be highly sensitive to J and slot aspect ratio. Lowest NO(x) emissions occurred when the dilution jet penetrated to approximately mid-radius. The viability of using 3D CFD analyses for optimizing jet mixing was demonstrated.

  10. Using tablet assisted Social Stories™ to improve classroom behavior for adolescents with intellectual disabilities.

    PubMed

    Kim, Mi-Seon; Blair, Kwang-Sun Cho; Lim, Kyoung-Won

    2014-09-01

    The present study examined the use of tablet assisted Social Stories™ intervention for three high school students with severe intellectual disabilities whose problem behavior interfered with their learning and caused classroom disruptions. A multiple probe design across participants was employed to test the impact of the tablet assisted SS on the participants' target behaviors. During intervention, the participants read the Social Stories that were created on Prezi and accessed via Quick Response (QR) codes using a Galaxy Tap smart tablet before participating in an academic period. Data indicated that the SS intervention decreased disruptive behavior and increased academic engagement in all three participants. All three demonstrated generalization of behaviors to a nontargeted academic period and maintenance of improved behaviors at the 2-week follow-up. Copyright © 2014 Elsevier Ltd. All rights reserved.

  11. QR encoded smart oral dosage forms by inkjet printing.

    PubMed

    Edinger, Magnus; Bar-Shalom, Daniel; Sandler, Niklas; Rantanen, Jukka; Genina, Natalja

    2018-01-30

    The use of inkjet printing (IJP) technology enables the flexible manufacturing of personalized medicine with the doses tailored for each patient. In this study we demonstrate, for the first time, the applicability of IJP in the production of edible dosage forms in the pattern of a quick response (QR) code. This printed pattern contains the drug itself and encoded information relevant to the patient and/or healthcare professionals. IJP of the active pharmaceutical ingredient (API)-containing ink in the pattern of QR code was performed onto a newly developed porous and flexible, but mechanically stable substrate with a good absorption capacity. The printing did not affect the mechanical properties of the substrate. The actual drug content of the printed dosage forms was in accordance with the encoded drug content. The QR encoded dosage forms had a good print definition without significant edge bleeding. They were readable by a smartphone even after storage in harsh conditions. This approach of efficient data incorporation and data storage combined with the use of smart devices can lead to safer and more patient-friendly drug products in the future. Copyright © 2017 Elsevier B.V. All rights reserved.

  12. Auditory Brainstem Response to Complex Sounds Predicts Self-Reported Speech-in-Noise Performance

    ERIC Educational Resources Information Center

    Anderson, Samira; Parbery-Clark, Alexandra; White-Schwoch, Travis; Kraus, Nina

    2013-01-01

    Purpose: To compare the ability of the auditory brainstem response to complex sounds (cABR) to predict subjective ratings of speech understanding in noise on the Speech, Spatial, and Qualities of Hearing Scale (SSQ; Gatehouse & Noble, 2004) relative to the predictive ability of the Quick Speech-in-Noise test (QuickSIN; Killion, Niquette,…

  13. Quick Fixes: Collection Development

    ERIC Educational Resources Information Center

    Nabb, Alicia

    2010-01-01

    The Do It Yourself (DIY) section is an essential and well-used part of the public library's collection and must be kept up-to-date to remain valuable, since tools, materials, and building codes are always changing. Current economic decline has increased the topic's popularity as homeowners choose to remodel rather than buy, or attempt to make…

  14. Computer Virus Protection

    ERIC Educational Resources Information Center

    Rajala, Judith B.

    2004-01-01

    A computer virus is a program--a piece of executable code--that has the unique ability to replicate. Like biological viruses, computer viruses can spread quickly and are often difficult to eradicate. They can attach themselves to just about any type of file, and are spread by replicating and being sent from one individual to another. Simply having…

  15. Tetrahedral Hohlraum Visualization and Pointings

    NASA Astrophysics Data System (ADS)

    Klare, K. A.; Wallace, J. M.; Drake, D.

    1997-11-01

    In designing experiments for Omega, the tetrahedral hohlraum (a sphere with four holes) can make full use of all 60 beams. There are some complications: the beams must clear the laser entrance hole (LEH), must miss a central capsule, absolutely must not go out the other LEHs, and should distribute in the interior of the hohlraum to maximize the uniformity of irradiation on the capsule while keeping reasonable laser spot sizes. We created a 15-offset coordinate system with which an IDL program computes clearances, writes a file for QuickDraw 3D (QD3D) visualization, and writes input for the viewfactor code RAYNA IV. Visualizing and adjusting the parameters by eye gave more reliable results than computer optimization. QD3D images permitted quick live rotations to determine offsets. The clearances obtained insured safe operation and good physics. The viewfactor code computes the initial irradiation of the hohlraum and capsule or of a uniform hohlraum source with the loss through the four LEHs and shows a high degree of uniformity with both, better for lasers because this deposits more energy near the LEHs to compensate for the holes.

  16. Rasch Model Analysis Gives New Insights Into the Structural Validity of the QuickDASH in Patients With Musculoskeletal Shoulder Pain.

    PubMed

    Jerosch-Herold, Christina; Chester, Rachel; Shepstone, Lee

    2017-09-01

    Study Design Cross-sectional secondary analysis of a prospective cohort study. Background The shortened version of the Disabilities of the Arm, Shoulder and Hand questionnaire (QuickDASH) is a widely used outcome measure that has been extensively evaluated using classical test theory. Rasch model analysis can identify strengths and weaknesses of rating scales and goes beyond classical test theory approaches. It uses a mathematical model to test the fit between the observed data and expected responses and converts ordinal-level scores into interval-level measurement. Objective To test the structural validity of the QuickDASH using Rasch analysis. Methods A prospective cohort study of 1030 patients with shoulder pain provided baseline data. Rasch analysis was conducted to (1) assess how the QuickDASH fits the Rasch model, (2) identify sources of misfit, and (3) explore potential solutions to these. Results There was evidence of multidimensionality and significant misfit to the Rasch model (χ 2 = 331.09, P<.001). Two items had disordered threshold responses with strong floor effects. Response bias was detected in most items for age and sex. Rescoring resulted in ordered thresholds; however, the 11-item scale still did not meet the expectations of the Rasch model. Conclusion Rasch model analysis on the QuickDASH has identified a number of problems that cannot be easily detected using traditional analyses. While revisions to the QuickDASH resulted in better fit, a "shoulder-specific" version is not advocated at present. Caution needs to be exercised when interpreting results of the QuickDASH outcome measure, as it does not meet the criteria for interval-level measurement and shows significant response bias by age and sex. J Orthop Sports Phys Ther 2017;47(9):664-672. Epub 13 Jul 2017. doi:10.2519/jospt.2017.7288.

  17. The MOLGENIS toolkit: rapid prototyping of biosoftware at the push of a button.

    PubMed

    Swertz, Morris A; Dijkstra, Martijn; Adamusiak, Tomasz; van der Velde, Joeri K; Kanterakis, Alexandros; Roos, Erik T; Lops, Joris; Thorisson, Gudmundur A; Arends, Danny; Byelas, George; Muilu, Juha; Brookes, Anthony J; de Brock, Engbert O; Jansen, Ritsert C; Parkinson, Helen

    2010-12-21

    There is a huge demand on bioinformaticians to provide their biologists with user friendly and scalable software infrastructures to capture, exchange, and exploit the unprecedented amounts of new *omics data. We here present MOLGENIS, a generic, open source, software toolkit to quickly produce the bespoke MOLecular GENetics Information Systems needed. The MOLGENIS toolkit provides bioinformaticians with a simple language to model biological data structures and user interfaces. At the push of a button, MOLGENIS' generator suite automatically translates these models into a feature-rich, ready-to-use web application including database, user interfaces, exchange formats, and scriptable interfaces. Each generator is a template of SQL, JAVA, R, or HTML code that would require much effort to write by hand. This 'model-driven' method ensures reuse of best practices and improves quality because the modeling language and generators are shared between all MOLGENIS applications, so that errors are found quickly and improvements are shared easily by a re-generation. A plug-in mechanism ensures that both the generator suite and generated product can be customized just as much as hand-written software. In recent years we have successfully evaluated the MOLGENIS toolkit for the rapid prototyping of many types of biomedical applications, including next-generation sequencing, GWAS, QTL, proteomics and biobanking. Writing 500 lines of model XML typically replaces 15,000 lines of hand-written programming code, which allows for quick adaptation if the information system is not yet to the biologist's satisfaction. Each application generated with MOLGENIS comes with an optimized database back-end, user interfaces for biologists to manage and exploit their data, programming interfaces for bioinformaticians to script analysis tools in R, Java, SOAP, REST/JSON and RDF, a tab-delimited file format to ease upload and exchange of data, and detailed technical documentation. Existing databases can be quickly enhanced with MOLGENIS generated interfaces using the 'ExtractModel' procedure. The MOLGENIS toolkit provides bioinformaticians with a simple model to quickly generate flexible web platforms for all possible genomic, molecular and phenotypic experiments with a richness of interfaces not provided by other tools. All the software and manuals are available free as LGPLv3 open source at http://www.molgenis.org.

  18. Genetic and epigenetic control of plant heat responses

    PubMed Central

    Liu, Junzhong; Feng, Lili; Li, Jianming; He, Zuhua

    2015-01-01

    Plants have evolved sophisticated genetic and epigenetic regulatory systems to respond quickly to unfavorable environmental conditions such as heat, cold, drought, and pathogen infections. In particular, heat greatly affects plant growth and development, immunity and circadian rhythm, and poses a serious threat to the global food supply. According to temperatures exposing, heat can be usually classified as warm ambient temperature (about 22–27°C), high temperature (27–30°C) and extremely high temperature (37–42°C, also known as heat stress) for the model plant Arabidopsis thaliana. The genetic mechanisms of plant responses to heat have been well studied, mainly focusing on elevated ambient temperature-mediated morphological acclimation and acceleration of flowering, modulation of circadian clock and plant immunity by high temperatures, and thermotolerance to heat stress. Recently, great progress has been achieved on epigenetic regulation of heat responses, including DNA methylation, histone modifications, histone variants, ATP-dependent chromatin remodeling, histone chaperones, small RNAs, long non-coding RNAs and other undefined epigenetic mechanisms. These epigenetic modifications regulate the expression of heat-responsive genes and function to prevent heat-related damages. This review focuses on recent progresses regarding the genetic and epigenetic control of heat responses in plants, and pays more attention to the role of the major epigenetic mechanisms in plant heat responses. Further research perspectives are also discussed. PMID:25964789

  19. GPS, BDS and Galileo ionospheric correction models: An evaluation in range delay and position domain

    NASA Astrophysics Data System (ADS)

    Wang, Ningbo; Li, Zishen; Li, Min; Yuan, Yunbin; Huo, Xingliang

    2018-05-01

    The performance of GPS Klobuchar (GPSKlob), BDS Klobuchar (BDSKlob) and NeQuick Galileo (NeQuickG) ionospheric correction models are evaluated in the range delay and position domains over China. The post-processed Klobuchar-style (CODKlob) coefficients provided by the Center for Orbit Determination in Europe (CODE) and our own fitted NeQuick coefficients (NeQuickC) are also included for comparison. In the range delay domain, BDS total electrons contents (TEC) derived from 20 international GNSS Monitoring and Assessment System (iGMAS) stations and GPS TEC obtained from 35 Crust Movement Observation Network of China (CMONC) stations are used as references. Compared to BDS TEC during the short period (doy 010-020, 2015), GPSKlob, BDSKlob and NeQuickG can correct 58.4, 66.7 and 54.7% of the ionospheric delay. Compared to GPS TEC for the long period (doy 001-180, 2015), the three ionospheric models can mitigate the ionospheric delay by 64.8, 65.4 and 68.1%, respectively. For the two comparison cases, CODKlob shows the worst performance, which only reduces 57.9% of the ionospheric range errors. NeQuickC exhibits the best performance, which outperforms GPSKlob, BDSKlob and NeQuickG by 6.7, 2.1 and 6.9%, respectively. In the position domain, single-frequency stand point positioning (SPP) was conducted at the selected 35 CMONC sites using GPS C/A pseudorange with and without ionospheric corrections. The vertical position error of the uncorrected case drops significantly from 10.3 m to 4.8, 4.6, 4.4 and 4.2 m for GPSKlob, CODKlob, BDSKlob and NeQuickG, however, the horizontal position error (3.2) merely decreases to 3.1, 2.7, 2.4 and 2.3 m, respectively. NeQuickG outperforms GPSKlob and BDSKlob by 5.8 and 1.9% in vertical component, and by 25.0 and 3.2% in horizontal component.

  20. Overcoming Codes and Standards Barriers to Innovations in Building Energy Efficiency

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cole, Pamala C.; Gilbride, Theresa L.

    2015-02-15

    In this journal article, the authors discuss approaches to overcoming building code barriers to energy-efficiency innovations in home construction. Building codes have been a highly motivational force for increasing the energy efficiency of new homes in the United States in recent years. But as quickly as the codes seem to be changing, new products are coming to the market at an even more rapid pace, sometimes offering approaches and construction techniques unthought of when the current code was first proposed, which might have been several years before its adoption by various jurisdictions. Due to this delay, the codes themselves canmore » become barriers to innovations that might otherwise be helping to further increase the efficiency, comfort, health or durability of new homes. . The U.S. Department of Energy’s Building America, a program dedicated to improving the energy efficiency of America’s housing stock through research and education, is working with the U.S. housing industry through its research teams to help builders identify and remove code barriers to innovation in the home construction industry. The article addresses several approaches that builders use to achieve approval for innovative building techniques when code barriers appear to exist.« less

  1. Comparisons of time explicit hybrid kinetic-fluid code Architect for Plasma Wakefield Acceleration with a full PIC code

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Massimo, F., E-mail: francesco.massimo@ensta-paristech.fr; Dipartimento SBAI, Università di Roma “La Sapienza“, Via A. Scarpa 14, 00161 Roma; Atzeni, S.

    Architect, a time explicit hybrid code designed to perform quick simulations for electron driven plasma wakefield acceleration, is described. In order to obtain beam quality acceptable for applications, control of the beam-plasma-dynamics is necessary. Particle in Cell (PIC) codes represent the state-of-the-art technique to investigate the underlying physics and possible experimental scenarios; however PIC codes demand the necessity of heavy computational resources. Architect code substantially reduces the need for computational resources by using a hybrid approach: relativistic electron bunches are treated kinetically as in a PIC code and the background plasma as a fluid. Cylindrical symmetry is assumed for themore » solution of the electromagnetic fields and fluid equations. In this paper both the underlying algorithms as well as a comparison with a fully three dimensional particle in cell code are reported. The comparison highlights the good agreement between the two models up to the weakly non-linear regimes. In highly non-linear regimes the two models only disagree in a localized region, where the plasma electrons expelled by the bunch close up at the end of the first plasma oscillation.« less

  2. Implications of Responsive Space on the Flight Software Architecture

    NASA Technical Reports Server (NTRS)

    Wilmot, Jonathan

    2006-01-01

    The Responsive Space initiative has several implications for flight software that need to be addressed not only within the run-time element, but the development infrastructure and software life-cycle process elements as well. The runtime element must at a minimum support Plug & Play, while the development and process elements need to incorporate methods to quickly generate the needed documentation, code, tests, and all of the artifacts required of flight quality software. Very rapid response times go even further, and imply little or no new software development, requiring instead, using only predeveloped and certified software modules that can be integrated and tested through automated methods. These elements have typically been addressed individually with significant benefits, but it is when they are combined that they can have the greatest impact to Responsive Space. The Flight Software Branch at NASA's Goddard Space Flight Center has been developing the runtime, infrastructure and process elements needed for rapid integration with the Core Flight software System (CFS) architecture. The CFS architecture consists of three main components; the core Flight Executive (cFE), the component catalog, and the Integrated Development Environment (DE). This paper will discuss the design of the components, how they facilitate rapid integration, and lessons learned as the architecture is utilized for an upcoming spacecraft.

  3. Meteor Shower Identification and Characterization with Python

    NASA Technical Reports Server (NTRS)

    Moorhead, Althea

    2015-01-01

    The short development time associated with Python and the number of astronomical packages available have led to increased usage within NASA. The Meteoroid Environment Office in particular uses the Python language for a number of applications, including daily meteor shower activity reporting, searches for potential parent bodies of meteor showers, and short dynamical simulations. We present our development of a meteor shower identification code that identifies statistically significant groups of meteors on similar orbits. This code overcomes several challenging characteristics of meteor showers such as drastic differences in uncertainties between meteors and between the orbital elements of a single meteor, and the variation of shower characteristics such as duration with age or planetary perturbations. This code has been proven to successfully and quickly identify unusual meteor activity such as the 2014 kappa Cygnid outburst. We present our algorithm along with these successes and discuss our plans for further code development.

  4. The Simple Video Coder: A free tool for efficiently coding social video data.

    PubMed

    Barto, Daniel; Bird, Clark W; Hamilton, Derek A; Fink, Brandi C

    2017-08-01

    Videotaping of experimental sessions is a common practice across many disciplines of psychology, ranging from clinical therapy, to developmental science, to animal research. Audio-visual data are a rich source of information that can be easily recorded; however, analysis of the recordings presents a major obstacle to project completion. Coding behavior is time-consuming and often requires ad-hoc training of a student coder. In addition, existing software is either prohibitively expensive or cumbersome, which leaves researchers with inadequate tools to quickly process video data. We offer the Simple Video Coder-free, open-source software for behavior coding that is flexible in accommodating different experimental designs, is intuitive for students to use, and produces outcome measures of event timing, frequency, and duration. Finally, the software also offers extraction tools to splice video into coded segments suitable for training future human coders or for use as input for pattern classification algorithms.

  5. Parallelization of ARC3D with Computer-Aided Tools

    NASA Technical Reports Server (NTRS)

    Jin, Haoqiang; Hribar, Michelle; Yan, Jerry; Saini, Subhash (Technical Monitor)

    1998-01-01

    A series of efforts have been devoted to investigating methods of porting and parallelizing applications quickly and efficiently for new architectures, such as the SCSI Origin 2000 and Cray T3E. This report presents the parallelization of a CFD application, ARC3D, using the computer-aided tools, Cesspools. Steps of parallelizing this code and requirements of achieving better performance are discussed. The generated parallel version has achieved reasonably well performance, for example, having a speedup of 30 for 36 Cray T3E processors. However, this performance could not be obtained without modification of the original serial code. It is suggested that in many cases improving serial code and performing necessary code transformations are important parts for the automated parallelization process although user intervention in many of these parts are still necessary. Nevertheless, development and improvement of useful software tools, such as Cesspools, can help trim down many tedious parallelization details and improve the processing efficiency.

  6. Ethical sensitivity intervention in science teacher education: Using computer simulations and professional codes of ethics

    NASA Astrophysics Data System (ADS)

    Holmes, Shawn Yvette

    A simulation was created to emulate two Racial Ethical Sensitivity Test (REST) videos (Brabeck et al., 2000). The REST is a reliable assessment for ethical sensitivity to racial and gender intolerant behaviors in educational settings. Quantitative and qualitative analysis of the REST was performed using the Quick-REST survey and an interview protocol. The purpose of this study was to affect science educator ability to recognize instances of racial and gender intolerant behaviors by levering immersive qualities of simulations. The fictitious Hazelton High School virtual environment was created by the researcher and compared with the traditional REST. The study investigated whether computer simulations can influence the ethical sensitivity of preservice and inservice science teachers to racial and gender intolerant behaviors in school settings. The post-test only research design involved 32 third-year science education students enrolled in science education classes at several southeastern universities and 31 science teachers from the same locale, some of which were part of an NSF project. Participant samples were assigned to the video control group or the simulation experimental group. This resulted in four comparison group; preservice video, preservice simulation, inservice video and inservice simulation. Participants experienced two REST scenarios in the appropriate format then responded to Quick-REST survey questions for both scenarios. Additionally, the simulation groups answered in-simulation and post-simulation questions. Nonparametric analysis of the Quick-REST ascertained differences between comparison groups. Cronbach's alpha was calculated for internal consistency. The REST interview protocol was used to analyze recognition of intolerant behaviors in the in-simulation prompts. Post-simulation prompts were analyzed for emergent themes concerning effect of the simulation on responses. The preservice video group had a significantly higher mean rank score than other comparison groups. There were no significant differences across the remaining groups. Qualitative analyses of in-simulation prompts suggest both preservice and inservice participants are unlikely to take action in an intolerant environment. Themes emerged in the post-simulation responses indicated participants viewed the simulation as a reflective, interactive, personal, and organic environment.

  7. Aluminum nanostructures with strong visible-range SERS activity for versatile micropatterning of molecular security labels.

    PubMed

    Lay, Chee Leng; Koh, Charlynn Sher Lin; Wang, Jing; Lee, Yih Hong; Jiang, Ruibin; Yang, Yijie; Yang, Zhe; Phang, In Yee; Ling, Xing Yi

    2018-01-03

    The application of aluminum (Al)-based nanostructures for visible-range plasmonics, especially for surface-enhanced Raman scattering (SERS), currently suffers from inconsistent local electromagnetic field distributions and/or inhomogeneous distribution of probe molecules. Herein, we lithographically fabricate structurally uniform Al nanostructures which enable homogeneous adsorption of various probe molecules. Individual Al nanostructures exhibit strong local electromagnetic field enhancements, in turn leading to intense SERS activity. The average SERS enhancement factor (EF) for individual nanostructures exceeds 10 4 for non-resonant probe molecules in the visible spectrum. These Al nanostructures also retain more than 70% of their original SERS intensities after one-month storage, displaying superb stability under ambient conditions. We further achieve tunable polarization-dependent SERS responses using anisotropic Al nanostructures, facilitating the design of sophisticated SERS-based security labels. Our micron-sized security label comprises two-tier security features, including a machine-readable hybrid quick-response (QR) code overlaid with a set of ciphertexts. Our work demonstrates the versatility of Al-based structures in low-cost modern chemical nano-analytics and forgery protection.

  8. Optical asymmetric cryptography based on elliptical polarized light linear truncation and a numerical reconstruction technique.

    PubMed

    Lin, Chao; Shen, Xueju; Wang, Zhisong; Zhao, Cheng

    2014-06-20

    We demonstrate a novel optical asymmetric cryptosystem based on the principle of elliptical polarized light linear truncation and a numerical reconstruction technique. The device of an array of linear polarizers is introduced to achieve linear truncation on the spatially resolved elliptical polarization distribution during image encryption. This encoding process can be characterized as confusion-based optical cryptography that involves no Fourier lens and diffusion operation. Based on the Jones matrix formalism, the intensity transmittance for this truncation is deduced to perform elliptical polarized light reconstruction based on two intensity measurements. Use of a quick response code makes the proposed cryptosystem practical, with versatile key sensitivity and fault tolerance. Both simulation and preliminary experimental results that support theoretical analysis are presented. An analysis of the resistance of the proposed method on a known public key attack is also provided.

  9. Calibration with MCNP of NaI detector for the determination of natural radioactivity levels in the field.

    PubMed

    Cinelli, Giorgia; Tositti, Laura; Mostacci, Domiziano; Baré, Jonathan

    2016-05-01

    In view of assessing natural radioactivity with on-site quantitative gamma spectrometry, efficiency calibration of NaI(Tl) detectors is investigated. A calibration based on Monte Carlo simulation of detector response is proposed, to render reliable quantitative analysis practicable in field campaigns. The method is developed with reference to contact geometry, in which measurements are taken placing the NaI(Tl) probe directly against the solid source to be analyzed. The Monte Carlo code used for the simulations was MCNP. Experimental verification of the calibration goodness is obtained by comparison with appropriate standards, as reported. On-site measurements yield a quick quantitative assessment of natural radioactivity levels present ((40)K, (238)U and (232)Th). On-site gamma spectrometry can prove particularly useful insofar as it provides information on materials from which samples cannot be taken. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

  10. Exploring the Effectiveness of Curriculum Provided Through Transmedia Books for Increasing Students' Knowledge and Interest in Science

    NASA Astrophysics Data System (ADS)

    Ponners, Pamela Jones

    Transmedia books are new and emerging technologies which are beginning to be used in current classrooms. Transmedia books are a traditional printed book that uses multiple media though the use of Quick Response (QR) codes and augmented reality (AR) triggers to access web-based technology. Using the transmedia book Skills That Engage Me students in kindergarten through second grade engage in curriculum designed to introduce science skills and careers. Using the modified Draw-a-Scientist Test (mDAST), observations and interviews, researchers analyzed pre and post data to describe changes students have about science and scientists. Future study may include the development and validation of a new instrument, Draw a Science Student, and examining the mDAST checklist with the intention of updating the parameters of what is considered positive and negative in relationship with work a scientist conducts.

  11. Quick concurrent responses to global and local cognitive information underlie intuitive understanding in board-game experts

    PubMed Central

    Nakatani, Hironori; Yamaguchi, Yoko

    2014-01-01

    Experts have the superior cognitive capability of quickly understanding complex information in their domain; however, little is known about the neural processes underlying this ability. Here, using a board game named shogi (Japanese chess), we investigated the brain activity in expert players that was involved in their quick understanding of board-game patterns. The frontal area responded only to meaningful game positions, whereas the temporal area responded to both game and random positions with the same latency (200 ms). Subsequent to these quick responses, the temporal and parietal areas responded only to game positions, with a latency of 700 ms. During the responses, enhanced phase synchronization between these areas was observed. Thus, experts first responded to global cognitive information that was specific to game positions and to local cognitive information that was common to game and random positions concurrently. These types of information were integrated via neural synchronization at the posterior areas. As these properties were specific to experts, much of the experts' advantage in understanding game positions occurred within 1 s of perception. PMID:25081320

  12. Entropy based file type identification and partitioning

    DTIC Science & Technology

    2017-06-01

    energy spectrum,” Proceedings of the Twenty-Ninth International Florida Artificial Intelligence Research Society Conference, pp. 288–293, 2016...ABBREVIATIONS AES Advanced Encryption Standard ANN Artificial Neural Network ASCII American Standard Code for Information Interchange CWT...the identification of file types and file partitioning. This approach has applications in cybersecurity as it allows for a quick determination of

  13. A hybrid symbolic/finite-element algorithm for solving nonlinear optimal control problems

    NASA Technical Reports Server (NTRS)

    Bless, Robert R.; Hodges, Dewey H.

    1991-01-01

    The general code described is capable of solving difficult nonlinear optimal control problems by using finite elements and a symbolic manipulator. Quick and accurate solutions are obtained with a minimum for user interaction. Since no user programming is required for most problems, there are tremendous savings to be gained in terms of time and money.

  14. 15 CFR 747.4 - Steps you must follow to apply for a SIRL.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... classifications, where available, as this will assist BIS to rule upon the application quickly. (2) Form BIS-748P... entity, the contract or work order which formed the basis of the transaction, and any identification number or project code for that contract or work order; (3) Explanation of how the project will...

  15. Data as a Service: A Seismic Web Service Pipeline

    NASA Astrophysics Data System (ADS)

    Martinez, E.

    2016-12-01

    Publishing data as a service pipeline provides an improved, dynamic approach over static data archives. A service pipeline is a collection of micro web services that each perform a specific task and expose the results of that task. Structured request/response formats allow micro web services to be chained together into a service pipeline to provide more complex results. The U.S. Geological Survey adopted service pipelines to publish seismic hazard and design data supporting both specific and generalized audiences. The seismic web service pipeline starts at source data and exposes probability and deterministic hazard curves, response spectra, risk-targeted ground motions, and seismic design provision metadata. This pipeline supports public/private organizations and individual engineers/researchers. Publishing data as a service pipeline provides a variety of benefits. Exposing the component services enables advanced users to inspect or use the data at each processing step. Exposing a composite service enables new users quick access to published data with a very low barrier to entry. Advanced users may re-use micro web services by chaining them in new ways or injecting new micros services into the pipeline. This allows the user to test hypothesis and compare their results to published results. Exposing data at each step in the pipeline enables users to review and validate the data and process more quickly and accurately. Making the source code open source, per USGS policy, further enables this transparency. Each micro service may be scaled independent of any other micro service. This ensures data remains available and timely in a cost-effective manner regardless of load. Additionally, if a new or more efficient approach to processing the data is discovered, this new approach may replace the old approach at any time, keeping the pipeline running while not affecting other micro services.

  16. TRIQS: A toolbox for research on interacting quantum systems

    NASA Astrophysics Data System (ADS)

    Parcollet, Olivier; Ferrero, Michel; Ayral, Thomas; Hafermann, Hartmut; Krivenko, Igor; Messio, Laura; Seth, Priyanka

    2015-11-01

    We present the TRIQS library, a Toolbox for Research on Interacting Quantum Systems. It is an open-source, computational physics library providing a framework for the quick development of applications in the field of many-body quantum physics, and in particular, strongly-correlated electronic systems. It supplies components to develop codes in a modern, concise and efficient way: e.g. Green's function containers, a generic Monte Carlo class, and simple interfaces to HDF5. TRIQS is a C++/Python library that can be used from either language. It is distributed under the GNU General Public License (GPLv3). State-of-the-art applications based on the library, such as modern quantum many-body solvers and interfaces between density-functional-theory codes and dynamical mean-field theory (DMFT) codes are distributed along with it.

  17. QSL Squasher: A Fast Quasi-separatrix Layer Map Calculator

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tassev, Svetlin; Savcheva, Antonia, E-mail: svetlin.tassev@cfa.harvard.edu

    Quasi-Separatrix Layers (QSLs) are a useful proxy for the locations where current sheets can develop in the solar corona, and give valuable information about the connectivity in complicated magnetic field configurations. However, calculating QSL maps, even for two-dimensional slices through three-dimensional models of coronal magnetic fields, is a non-trivial task, as it usually involves tracing out millions of magnetic field lines with immense precision. Thus, extending QSL calculations to three dimensions has rarely been done until now. In order to address this challenge, we present QSL Squasher—a public, open-source code, which is optimized for calculating QSL maps in both twomore » and three dimensions on graphics processing units. The code achieves large processing speeds for three reasons, each of which results in an order-of-magnitude speed-up. (1) The code is parallelized using OpenCL. (2) The precision requirements for the QSL calculation are drastically reduced by using perturbation theory. (3) A new boundary detection criterion between quasi-connectivity domains is used, which quickly identifies possible QSL locations that need to be finely sampled by the code. That boundary detection criterion relies on finding the locations of abrupt field-line length changes, which we do by introducing a new Field-line Length Edge (FLEDGE) map. We find FLEDGE maps useful on their own as a quick-and-dirty substitute for QSL maps. QSL Squasher allows construction of high-resolution 3D FLEDGE maps in a matter of minutes, which is two orders of magnitude faster than calculating the corresponding 3D QSL maps. We include a sample of calculations done using QSL Squasher to demonstrate its capabilities as a QSL calculator, as well as to compare QSL and FLEDGE maps.« less

  18. Proper coding of the Abbreviated Injury Scale: can clinical parameters help as surrogates in estimating blood loss?

    PubMed

    Burkhardt, M; Holstein, J H; Moersdorf, P; Kristen, A; Lefering, R; Pohlemann, T; Pizanis, A

    2014-08-01

    The Abbreviated Injury Scale (AIS) requires the estimation of the lost blood volume for some severity assignments. This study aimed to develop a rule of thumb for facilitating AIS coding by using objective clinical parameters as surrogate markers of blood loss. Using the example of pelvic ring fractures, a retrospective analysis of TraumaRegister DGU(®) data from 2002 to 2011 was performed. As potential surrogate markers of blood loss, we recorded the hemoglobin (Hb) level, systolic blood pressure (SBP), base excess (BE), Quick's value, units of packed red blood cells (PRBCs) transfused before intensive care unit (ICU) admission, and mortality within 24 h. We identified 11,574 patients with pelvic ring fractures (Tile/OTA classification: 39 % type A, 40 % type B, 21 % type C). Type C fractures were 73.1 % AISpelvis 4 and 26.9 % AISpelvis 5. Type B fractures were 47 % AISpelvis 3, 47 % AISpelvis 4, and 6 % AISpelvis 5. In type C fractures, cut-off values of <7 g/dL Hb, <90 mmHg SBP, <-9 mmol/L BE, <35 % Quick's value, >15 units PRBCs, and death within 24 h had a positive predictive value of 47 % and a sensitivity of 62 % for AISpelvis 5. In type B fractures, these cut-off values had poor sensitivity (48 %) and positive predictive value (11 %) for AISpelvis 5. We failed to develop a rule of thumb for facilitating a proper future AIS coding using the example of pelvic ring fractures. The estimation of blood loss for severity assignment still remains a noteworthy weakness in the AIS coding of traumatic injuries.

  19. QSL Squasher: A Fast Quasi-separatrix Layer Map Calculator

    NASA Astrophysics Data System (ADS)

    Tassev, Svetlin; Savcheva, Antonia

    2017-05-01

    Quasi-Separatrix Layers (QSLs) are a useful proxy for the locations where current sheets can develop in the solar corona, and give valuable information about the connectivity in complicated magnetic field configurations. However, calculating QSL maps, even for two-dimensional slices through three-dimensional models of coronal magnetic fields, is a non-trivial task, as it usually involves tracing out millions of magnetic field lines with immense precision. Thus, extending QSL calculations to three dimensions has rarely been done until now. In order to address this challenge, we present QSL Squasher—a public, open-source code, which is optimized for calculating QSL maps in both two and three dimensions on graphics processing units. The code achieves large processing speeds for three reasons, each of which results in an order-of-magnitude speed-up. (1) The code is parallelized using OpenCL. (2) The precision requirements for the QSL calculation are drastically reduced by using perturbation theory. (3) A new boundary detection criterion between quasi-connectivity domains is used, which quickly identifies possible QSL locations that need to be finely sampled by the code. That boundary detection criterion relies on finding the locations of abrupt field-line length changes, which we do by introducing a new Field-line Length Edge (FLEDGE) map. We find FLEDGE maps useful on their own as a quick-and-dirty substitute for QSL maps. QSL Squasher allows construction of high-resolution 3D FLEDGE maps in a matter of minutes, which is two orders of magnitude faster than calculating the corresponding 3D QSL maps. We include a sample of calculations done using QSL Squasher to demonstrate its capabilities as a QSL calculator, as well as to compare QSL and FLEDGE maps.

  20. Spatial Resolution Characterization for QuickBird Image Products 2003-2004 Season

    NASA Technical Reports Server (NTRS)

    Blonski, Slawomir

    2006-01-01

    This presentation focuses on spatial resolution characterization for QuickBird panochromatic images in 2003-2004 and presents data measurements and analysis of SSC edge target deployment and edge response extraction and modeling. The results of the characterization are shown as values of the Modulation Transfer Function (MTF) at the Nyquist spatial frequency and as the Relative Edge Response (RER) components. The results show that RER is much less sensitive to accuracy of the curve fitting than the value of MTF at Nyquist frequency. Therefore, the RER/edge response slope is a more robust estimator of the digital image spatial resolution than the MTF. For the QuickBird panochromatic images, the RER is consistently equal to 0.5 for images processed with the Cubic Convolution resampling and to 0.8 for the MTF resampling.

  1. Using nitrate to quantify quick flow in a karst aquifer

    USGS Publications Warehouse

    Mahler, B.J.; Garner, B.D.

    2009-01-01

    In karst aquifers, contaminated recharge can degrade spring water quality, but quantifying the rapid recharge (quick flow) component of spring flow is challenging because of its temporal variability. Here, we investigate the use of nitrate in a two-endmember mixing model to quantify quick flow in Barton Springs, Austin, Texas. Historical nitrate data from recharging creeks and Barton Springs were evaluated to determine a representative nitrate concentration for the aquifer water endmember (1.5 mg/L) and the quick flow endmember (0.17 mg/L for nonstormflow conditions and 0.25 mg/L for stormflow conditions). Under nonstormflow conditions for 1990 to 2005, model results indicated that quick flow contributed from 0% to 55% of spring flow. The nitrate-based two-endmember model was applied to the response of Barton Springs to a storm and results compared to those produced using the same model with ??18O and specific conductance (SC) as tracers. Additionally, the mixing model was modified to allow endmember quick flow values to vary over time. Of the three tracers, nitrate appears to be the most advantageous because it is conservative and because the difference between the concentrations in the two endmembers is large relative to their variance. The ??18O- based model was very sensitive to variability within the quick flow endmember, and SC was not conservative over the timescale of the storm response. We conclude that a nitrate-based two-endmember mixing model might provide a useful approach for quantifying the temporally variable quick flow component of spring flow in some karst systems. ?? 2008 National Ground Water Association.

  2. Development and evaluation of a Naïve Bayesian model for coding causation of workers' compensation claims.

    PubMed

    Bertke, S J; Meyers, A R; Wurzelbacher, S J; Bell, J; Lampl, M L; Robins, D

    2012-12-01

    Tracking and trending rates of injuries and illnesses classified as musculoskeletal disorders caused by ergonomic risk factors such as overexertion and repetitive motion (MSDs) and slips, trips, or falls (STFs) in different industry sectors is of high interest to many researchers. Unfortunately, identifying the cause of injuries and illnesses in large datasets such as workers' compensation systems often requires reading and coding the free form accident text narrative for potentially millions of records. To alleviate the need for manual coding, this paper describes and evaluates a computer auto-coding algorithm that demonstrated the ability to code millions of claims quickly and accurately by learning from a set of previously manually coded claims. The auto-coding program was able to code claims as a musculoskeletal disorders, STF or other with approximately 90% accuracy. The program developed and discussed in this paper provides an accurate and efficient method for identifying the causation of workers' compensation claims as a STF or MSD in a large database based on the unstructured text narrative and resulting injury diagnoses. The program coded thousands of claims in minutes. The method described in this paper can be used by researchers and practitioners to relieve the manual burden of reading and identifying the causation of claims as a STF or MSD. Furthermore, the method can be easily generalized to code/classify other unstructured text narratives. Published by Elsevier Ltd.

  3. The CARMEN software as a service infrastructure.

    PubMed

    Weeks, Michael; Jessop, Mark; Fletcher, Martyn; Hodge, Victoria; Jackson, Tom; Austin, Jim

    2013-01-28

    The CARMEN platform allows neuroscientists to share data, metadata, services and workflows, and to execute these services and workflows remotely via a Web portal. This paper describes how we implemented a service-based infrastructure into the CARMEN Virtual Laboratory. A Software as a Service framework was developed to allow generic new and legacy code to be deployed as services on a heterogeneous execution framework. Users can submit analysis code typically written in Matlab, Python, C/C++ and R as non-interactive standalone command-line applications and wrap them as services in a form suitable for deployment on the platform. The CARMEN Service Builder tool enables neuroscientists to quickly wrap their analysis software for deployment to the CARMEN platform, as a service without knowledge of the service framework or the CARMEN system. A metadata schema describes each service in terms of both system and user requirements. The search functionality allows services to be quickly discovered from the many services available. Within the platform, services may be combined into more complicated analyses using the workflow tool. CARMEN and the service infrastructure are targeted towards the neuroscience community; however, it is a generic platform, and can be targeted towards any discipline.

  4. Next stop for the CRISPR revolution: RNA-guided epigenetic regulators.

    PubMed

    Vora, Suhani; Tuttle, Marcelle; Cheng, Jenny; Church, George

    2016-09-01

    Clustered regularly interspaced short palindromic repeats (CRISPRs) and CRISPR-associated (Cas) proteins offer a breakthrough platform for cheap, programmable, and effective sequence-specific DNA targeting. The CRISPR-Cas system is naturally equipped for targeted DNA cutting through its native nuclease activity. As such, groups researching a broad spectrum of biological organisms have quickly adopted the technology with groundbreaking applications to genomic sequence editing in over 20 different species. However, the biological code of life is not only encoded in genetics but also in epigenetics as well. While genetic sequence editing is a powerful ability, we must also be able to edit and regulate transcriptional and epigenetic code. Taking inspiration from work on earlier sequence-specific targeting technologies such as zinc fingers (ZFs) and transcription activator-like effectors (TALEs), researchers quickly expanded the CRISPR-Cas toolbox to include transcriptional activation, repression, and epigenetic modification. In this review, we highlight advances that extend the CRISPR-Cas toolkit for transcriptional and epigenetic regulation, as well as best practice guidelines for these tools, and a perspective on future applications. © 2016 The Authors. The FEBS Journal published by John Wiley & Sons Ltd on behalf of Federation of European Biochemical Societies.

  5. A Graphical User-Interface for Propulsion System Analysis

    NASA Technical Reports Server (NTRS)

    Curlett, Brian P.; Ryall, Kathleen

    1992-01-01

    NASA LeRC uses a series of computer codes to calculate installed propulsion system performance and weight. The need to evaluate more advanced engine concepts with a greater degree of accuracy has resulted in an increase in complexity of this analysis system. Therefore, a graphical user interface was developed to allow the analyst to more quickly and easily apply these codes. The development of this interface and the rationale for the approach taken are described. The interface consists of a method of pictorially representing and editing the propulsion system configuration, forms for entering numerical data, on-line help and documentation, post processing of data, and a menu system to control execution.

  6. A graphical user-interface for propulsion system analysis

    NASA Technical Reports Server (NTRS)

    Curlett, Brian P.; Ryall, Kathleen

    1993-01-01

    NASA LeRC uses a series of computer codes to calculate installed propulsion system performance and weight. The need to evaluate more advanced engine concepts with a greater degree of accuracy has resulted in an increase in complexity of this analysis system. Therefore, a graphical user interface was developed to allow the analyst to more quickly and easily apply these codes. The development of this interface and the rationale for the approach taken are described. The interface consists of a method of pictorially representing and editing the propulsion system configuration, forms for entering numerical data, on-line help and documentation, post processing of data, and a menu system to control execution.

  7. Asthma and Respiratory Foundation NZ adult asthma guidelines: a quick reference guide.

    PubMed

    Beasley, Richard; Hancox, Robert J; Harwood, Matire; Perrin, Kyle; Poot, Betty; Pilcher, Janine; Reid, Jim; Talemaitoga, Api; Thayabaran, Darmiga

    2016-11-18

    The purpose of the Asthma and Respiratory Foundation NZ Adult Asthma Guidelines is to provide simple, practical and evidence-based recommendations for the diagnosis, assessment and management of asthma in adults (aged 16 and over) in a quick reference format. The intended users are health professionals responsible for delivering asthma care in the community and hospital Emergency Department settings, and those responsible for the training of such health professionals.

  8. Parallelization of Finite Element Analysis Codes Using Heterogeneous Distributed Computing

    NASA Technical Reports Server (NTRS)

    Ozguner, Fusun

    1996-01-01

    Performance gains in computer design are quickly consumed as users seek to analyze larger problems to a higher degree of accuracy. Innovative computational methods, such as parallel and distributed computing, seek to multiply the power of existing hardware technology to satisfy the computational demands of large applications. In the early stages of this project, experiments were performed using two large, coarse-grained applications, CSTEM and METCAN. These applications were parallelized on an Intel iPSC/860 hypercube. It was found that the overall speedup was very low, due to large, inherently sequential code segments present in the applications. The overall execution time T(sub par), of the application is dependent on these sequential segments. If these segments make up a significant fraction of the overall code, the application will have a poor speedup measure.

  9. Analysis Of AVIRIS Data From LEO-15 Using Tafkaa Atmospheric Correction

    NASA Technical Reports Server (NTRS)

    Montes, Marcos J.; Gao, Bo-Cai; Davis, Curtiss O.; Moline, Mark

    2004-01-01

    We previously developed an algorithm named Tafkaa for atmospheric correction of remote sensing ocean color data from aircraft and satellite platforms. The algorithm allows quick atmospheric correction of hyperspectral data using lookup tables generated with a modified version of Ahmad & Fraser s vector radiative transfer code. During the past few years we have extended the capabilities of the code. Current modifications include the ability to account for within scene variation in solar geometry (important for very long scenes) and view geometries (important for wide fields of view). Additionally, versions of Tafkaa have been made for a variety of multi-spectral sensors, including SeaWiFS and MODIS. In this proceeding we present some initial results of atmospheric correction of AVIRIS data from the 2001 July Hyperspectral Coastal Ocean Dynamics Experiment (HyCODE) at LEO-15.

  10. Software user's guide for determining the Pennsylvania scour critical indicator code and streambed scour assessment rating for roadway bridges

    USGS Publications Warehouse

    Henneberg, M.F.; Strause, J.L.

    2002-01-01

    This report presents the instructions required to use the Scour Critical Bridge Indicator (SCBI) Code and Scour Assessment Rating (SAR) calculator developed by the Pennsylvania Department of Transportation (PennDOT) and the U.S. Geological Survey to identify Pennsylvania bridges with excessive scour conditions or a high potential for scour. Use of the calculator will enable PennDOT bridge personnel to quickly calculate these scour indices if site conditions change, new bridges are constructed, or new information needs to be included. Both indices are calculated for a bridge simultaneously because they must be used together to be interpreted accurately. The SCBI Code and SAR calculator program is run by a World Wide Web browser from a remote computer. The user can 1) add additional scenarios for bridges in the SCBI Code and SAR calculator database or 2) enter data for new bridges and run the program to calculate the SCBI Code and calculate the SAR. The calculator program allows the user to print the results and to save multiple scenarios for a bridge.

  11. The MOLGENIS toolkit: rapid prototyping of biosoftware at the push of a button

    PubMed Central

    2010-01-01

    Background There is a huge demand on bioinformaticians to provide their biologists with user friendly and scalable software infrastructures to capture, exchange, and exploit the unprecedented amounts of new *omics data. We here present MOLGENIS, a generic, open source, software toolkit to quickly produce the bespoke MOLecular GENetics Information Systems needed. Methods The MOLGENIS toolkit provides bioinformaticians with a simple language to model biological data structures and user interfaces. At the push of a button, MOLGENIS’ generator suite automatically translates these models into a feature-rich, ready-to-use web application including database, user interfaces, exchange formats, and scriptable interfaces. Each generator is a template of SQL, JAVA, R, or HTML code that would require much effort to write by hand. This ‘model-driven’ method ensures reuse of best practices and improves quality because the modeling language and generators are shared between all MOLGENIS applications, so that errors are found quickly and improvements are shared easily by a re-generation. A plug-in mechanism ensures that both the generator suite and generated product can be customized just as much as hand-written software. Results In recent years we have successfully evaluated the MOLGENIS toolkit for the rapid prototyping of many types of biomedical applications, including next-generation sequencing, GWAS, QTL, proteomics and biobanking. Writing 500 lines of model XML typically replaces 15,000 lines of hand-written programming code, which allows for quick adaptation if the information system is not yet to the biologist’s satisfaction. Each application generated with MOLGENIS comes with an optimized database back-end, user interfaces for biologists to manage and exploit their data, programming interfaces for bioinformaticians to script analysis tools in R, Java, SOAP, REST/JSON and RDF, a tab-delimited file format to ease upload and exchange of data, and detailed technical documentation. Existing databases can be quickly enhanced with MOLGENIS generated interfaces using the ‘ExtractModel’ procedure. Conclusions The MOLGENIS toolkit provides bioinformaticians with a simple model to quickly generate flexible web platforms for all possible genomic, molecular and phenotypic experiments with a richness of interfaces not provided by other tools. All the software and manuals are available free as LGPLv3 open source at http://www.molgenis.org. PMID:21210979

  12. Legacy Code Modernization

    NASA Technical Reports Server (NTRS)

    Hribar, Michelle R.; Frumkin, Michael; Jin, Haoqiang; Waheed, Abdul; Yan, Jerry; Saini, Subhash (Technical Monitor)

    1998-01-01

    Over the past decade, high performance computing has evolved rapidly; systems based on commodity microprocessors have been introduced in quick succession from at least seven vendors/families. Porting codes to every new architecture is a difficult problem; in particular, here at NASA, there are many large CFD applications that are very costly to port to new machines by hand. The LCM ("Legacy Code Modernization") Project is the development of an integrated parallelization environment (IPE) which performs the automated mapping of legacy CFD (Fortran) applications to state-of-the-art high performance computers. While most projects to port codes focus on the parallelization of the code, we consider porting to be an iterative process consisting of several steps: 1) code cleanup, 2) serial optimization,3) parallelization, 4) performance monitoring and visualization, 5) intelligent tools for automated tuning using performance prediction and 6) machine specific optimization. The approach for building this parallelization environment is to build the components for each of the steps simultaneously and then integrate them together. The demonstration will exhibit our latest research in building this environment: 1. Parallelizing tools and compiler evaluation. 2. Code cleanup and serial optimization using automated scripts 3. Development of a code generator for performance prediction 4. Automated partitioning 5. Automated insertion of directives. These demonstrations will exhibit the effectiveness of an automated approach for all the steps involved with porting and tuning a legacy code application for a new architecture.

  13. Different kernel functions due to rainfall response from borehole strainmeter in Taiwan

    NASA Astrophysics Data System (ADS)

    Yen Chen, Chih; Hu, Jyr Ching; LIu, Chi Ching

    2014-05-01

    In order to realize reasons inducing earthquakes, project of monitoring of the fault activity using 3-component Gladwin Tensor Strainmeter (GTSM) has been initiated since 2003 in Taiwan, which is one of the most active seismic regions in the world. Observed strain contains several different effects within including barometric, tidal, groundwater, precipitation, tectonics, seismic and other irregular noise. After removing the response of tides and air pressure on strain, we still can find some anomalies highly related to the rainfall in short time in days. The strain response induced by rainfall can be separated into two parts as observation in groundwater, slow response and quick response, respectively. Quick response reflects the strain responding to the load of falling water drops on the ground surface. A kernel function shows the continual response induced by unit precipitation water in time domain. We split the quick response from data removing tidal and barometric response, and then calculate the kernel function by use of deconvolution method. More, an average kernel function was calculated to reduce the noise level. There are five of the sites installed by CGS Taiwan were selected to calculate kernel functions for individual sites. The results show there may be different on rainfall response in different environmental settings. In the case of stations site on gentle terrain, kernel function for each site shows the similar trend, it rises quickly to maximum in 1 to 2 hrs, and then goes down near to zero gently in period of 2-3 days. But in the case of sites settled side by the rivers, there will be 2nd peak of function when collected water in the catchment flows along by the sites related to the hydrograph of creeks. More, landslides will occur in some sites in hazard of landslide with more rainfall stored on, just like DARB in ChiaYi. The curve of kernel function will be controlled by landslides and debris flows.

  14. The diagnosis related groups enhanced electronic medical record.

    PubMed

    Müller, Marcel Lucas; Bürkle, Thomas; Irps, Sebastian; Roeder, Norbert; Prokosch, Hans-Ulrich

    2003-07-01

    The introduction of Diagnosis Related Groups as a basis for hospital payment in Germany announced essential changes in the hospital reimbursement practice. A hospital's economical survival will depend vitally on the accuracy and completeness of the documentation of DRG relevant data like diagnosis and procedure codes. In order to enhance physicians' coding compliance, an easy-to-use interface integrating coding tasks seamlessly into clinical routine had to be developed. A generic approach should access coding and clinical guidelines from different information sources. Within the Electronic Medical Record (EMR) a user interface ('DRG Control Center') for all DRG relevant clinical and administrative data has been built. A comprehensive DRG-related web site gives online access to DRG grouping software and an electronic coding expert. Both components are linked together using an application supporting bi-directional communication. Other web based services like a guideline search engine can be integrated as well. With the proposed method, the clinician gains quick access to context sensitive clinical guidelines for appropriate treatment of his/her patient and administrative guidelines for the adequate coding of the diagnoses and procedures. This paper describes the design and current implementation and discusses our experiences.

  15. ANNA: A Convolutional Neural Network Code for Spectroscopic Analysis

    NASA Astrophysics Data System (ADS)

    Lee-Brown, Donald; Anthony-Twarog, Barbara J.; Twarog, Bruce A.

    2018-01-01

    We present ANNA, a Python-based convolutional neural network code for the automated analysis of stellar spectra. ANNA provides a flexible framework that allows atmospheric parameters such as temperature and metallicity to be determined with accuracies comparable to those of established but less efficient techniques. ANNA performs its parameterization extremely quickly; typically several thousand spectra can be analyzed in less than a second. Additionally, the code incorporates features which greatly speed up the training process necessary for the neural network to measure spectra accurately, resulting in a tool that can easily be run on a single desktop or laptop computer. Thus, ANNA is useful in an era when spectrographs increasingly have the capability to collect dozens to hundreds of spectra each night. This talk will cover the basic features included in ANNA and demonstrate its performance in two use cases: an open cluster abundance analysis involving several hundred spectra, and a metal-rich field star study. Applicability of the code to large survey datasets will also be discussed.

  16. Applications of automatic differentiation in computational fluid dynamics

    NASA Technical Reports Server (NTRS)

    Green, Lawrence L.; Carle, A.; Bischof, C.; Haigler, Kara J.; Newman, Perry A.

    1994-01-01

    Automatic differentiation (AD) is a powerful computational method that provides for computing exact sensitivity derivatives (SD) from existing computer programs for multidisciplinary design optimization (MDO) or in sensitivity analysis. A pre-compiler AD tool for FORTRAN programs called ADIFOR has been developed. The ADIFOR tool has been easily and quickly applied by NASA Langley researchers to assess the feasibility and computational impact of AD in MDO with several different FORTRAN programs. These include a state-of-the-art three dimensional multigrid Navier-Stokes flow solver for wings or aircraft configurations in transonic turbulent flow. With ADIFOR the user specifies sets of independent and dependent variables with an existing computer code. ADIFOR then traces the dependency path throughout the code, applies the chain rule to formulate derivative expressions, and generates new code to compute the required SD matrix. The resulting codes have been verified to compute exact non-geometric and geometric SD for a variety of cases. in less time than is required to compute the SD matrix using centered divided differences.

  17. GIZMO: Multi-method magneto-hydrodynamics+gravity code

    NASA Astrophysics Data System (ADS)

    Hopkins, Philip F.

    2014-10-01

    GIZMO is a flexible, multi-method magneto-hydrodynamics+gravity code that solves the hydrodynamic equations using a variety of different methods. It introduces new Lagrangian Godunov-type methods that allow solving the fluid equations with a moving particle distribution that is automatically adaptive in resolution and avoids the advection errors, angular momentum conservation errors, and excessive diffusion problems that seriously limit the applicability of “adaptive mesh” (AMR) codes, while simultaneously avoiding the low-order errors inherent to simpler methods like smoothed-particle hydrodynamics (SPH). GIZMO also allows the use of SPH either in “traditional” form or “modern” (more accurate) forms, or use of a mesh. Self-gravity is solved quickly with a BH-Tree (optionally a hybrid PM-Tree for periodic boundaries) and on-the-fly adaptive gravitational softenings. The code is descended from P-GADGET, itself descended from GADGET-2 (ascl:0003.001), and many of the naming conventions remain (for the sake of compatibility with the large library of GADGET work and analysis software).

  18. Enhancing Application Performance Using Mini-Apps: Comparison of Hybrid Parallel Programming Paradigms

    NASA Technical Reports Server (NTRS)

    Lawson, Gary; Sosonkina, Masha; Baurle, Robert; Hammond, Dana

    2017-01-01

    In many fields, real-world applications for High Performance Computing have already been developed. For these applications to stay up-to-date, new parallel strategies must be explored to yield the best performance; however, restructuring or modifying a real-world application may be daunting depending on the size of the code. In this case, a mini-app may be employed to quickly explore such options without modifying the entire code. In this work, several mini-apps have been created to enhance a real-world application performance, namely the VULCAN code for complex flow analysis developed at the NASA Langley Research Center. These mini-apps explore hybrid parallel programming paradigms with Message Passing Interface (MPI) for distributed memory access and either Shared MPI (SMPI) or OpenMP for shared memory accesses. Performance testing shows that MPI+SMPI yields the best execution performance, while requiring the largest number of code changes. A maximum speedup of 23 was measured for MPI+SMPI, but only 11 was measured for MPI+OpenMP.

  19. Design of a Low Aspect Ratio Transonic Compressor Stage Using CFD Techniques

    NASA Technical Reports Server (NTRS)

    Sanger, Nelson L.

    1994-01-01

    A transonic compressor stage has been designed for the Naval Postgraduate School Turbopropulsion Laboratory. The design relied heavily on CFD techniques while minimizing conventional empirical design methods. The low aspect ratio (1.2) rotor has been designed for a specific head ratio of .25 and a tip relative inlet Mach number of 1.3. Overall stage pressure ratio is 1.56. The rotor was designed using an Euler code augmented by a distributed body force model to account for viscous effects. This provided a relatively quick-running design tool, and was used for both rotor and stator calculations. The initial stator sections were sized using a compressible, cascade panel code. In addition to being used as a case study for teaching purposes, the compressor stage will be used as a research stage. Detailed measurements, including non-intrusive LDV, will be compared with the design computations, and with the results of other CFD codes, as a means of assessing and improving the computational codes as design tools.

  20. AirShow 1.0 CFD Software Users' Guide

    NASA Technical Reports Server (NTRS)

    Mohler, Stanley R., Jr.

    2005-01-01

    AirShow is visualization post-processing software for Computational Fluid Dynamics (CFD). Upon reading binary PLOT3D grid and solution files into AirShow, the engineer can quickly see how hundreds of complex 3-D structured blocks are arranged and numbered. Additionally, chosen grid planes can be displayed and colored according to various aerodynamic flow quantities such as Mach number and pressure. The user may interactively rotate and translate the graphical objects using the mouse. The software source code was written in cross-platform Java, C++, and OpenGL, and runs on Unix, Linux, and Windows. The graphical user interface (GUI) was written using Java Swing. Java also provides multiple synchronized threads. The Java Native Interface (JNI) provides a bridge between the Java code and the C++ code where the PLOT3D files are read, the OpenGL graphics are rendered, and numerical calculations are performed. AirShow is easy to learn and simple to use. The source code is available for free from the NASA Technology Transfer and Partnership Office.

  1. Medial Prefrontal Cortex Reduces Memory Interference by Modifying Hippocampal Encoding

    PubMed Central

    Guise, Kevin G.; Shapiro, Matthew L.

    2017-01-01

    Summary The prefrontal cortex (PFC) is crucial for accurate memory performance when prior knowledge interferes with new learning, but the mechanisms that minimize proactive interference are unknown. To investigate these, we assessed the influence of medial PFC (mPFC) activity on spatial learning and hippocampal coding in a plus maze task that requires both structures. mPFC inactivation did not impair spatial learning or retrieval per se, but impaired the ability to follow changing spatial rules. mPFC and CA1 ensembles recorded simultaneously predicted goal choices and tracked changing rules; inactivating mPFC attenuated CA1 prospective coding. mPFC activity modified CA1 codes during learning, which in turn predicted how quickly rats adapted to subsequent rule changes. The results suggest that task rules signaled by the mPFC become incorporated into hippocampal representations and support prospective coding. By this mechanism, mPFC activity prevents interference by “teaching” the hippocampus to retrieve distinct representations of similar circumstances. PMID:28343868

  2. Immunochromatographic diagnostic test analysis using Google Glass.

    PubMed

    Feng, Steve; Caire, Romain; Cortazar, Bingen; Turan, Mehmet; Wong, Andrew; Ozcan, Aydogan

    2014-03-25

    We demonstrate a Google Glass-based rapid diagnostic test (RDT) reader platform capable of qualitative and quantitative measurements of various lateral flow immunochromatographic assays and similar biomedical diagnostics tests. Using a custom-written Glass application and without any external hardware attachments, one or more RDTs labeled with Quick Response (QR) code identifiers are simultaneously imaged using the built-in camera of the Google Glass that is based on a hands-free and voice-controlled interface and digitally transmitted to a server for digital processing. The acquired JPEG images are automatically processed to locate all the RDTs and, for each RDT, to produce a quantitative diagnostic result, which is returned to the Google Glass (i.e., the user) and also stored on a central server along with the RDT image, QR code, and other related information (e.g., demographic data). The same server also provides a dynamic spatiotemporal map and real-time statistics for uploaded RDT results accessible through Internet browsers. We tested this Google Glass-based diagnostic platform using qualitative (i.e., yes/no) human immunodeficiency virus (HIV) and quantitative prostate-specific antigen (PSA) tests. For the quantitative RDTs, we measured activated tests at various concentrations ranging from 0 to 200 ng/mL for free and total PSA. This wearable RDT reader platform running on Google Glass combines a hands-free sensing and image capture interface with powerful servers running our custom image processing codes, and it can be quite useful for real-time spatiotemporal tracking of various diseases and personal medical conditions, providing a valuable tool for epidemiology and mobile health.

  3. Immunochromatographic Diagnostic Test Analysis Using Google Glass

    PubMed Central

    2014-01-01

    We demonstrate a Google Glass-based rapid diagnostic test (RDT) reader platform capable of qualitative and quantitative measurements of various lateral flow immunochromatographic assays and similar biomedical diagnostics tests. Using a custom-written Glass application and without any external hardware attachments, one or more RDTs labeled with Quick Response (QR) code identifiers are simultaneously imaged using the built-in camera of the Google Glass that is based on a hands-free and voice-controlled interface and digitally transmitted to a server for digital processing. The acquired JPEG images are automatically processed to locate all the RDTs and, for each RDT, to produce a quantitative diagnostic result, which is returned to the Google Glass (i.e., the user) and also stored on a central server along with the RDT image, QR code, and other related information (e.g., demographic data). The same server also provides a dynamic spatiotemporal map and real-time statistics for uploaded RDT results accessible through Internet browsers. We tested this Google Glass-based diagnostic platform using qualitative (i.e., yes/no) human immunodeficiency virus (HIV) and quantitative prostate-specific antigen (PSA) tests. For the quantitative RDTs, we measured activated tests at various concentrations ranging from 0 to 200 ng/mL for free and total PSA. This wearable RDT reader platform running on Google Glass combines a hands-free sensing and image capture interface with powerful servers running our custom image processing codes, and it can be quite useful for real-time spatiotemporal tracking of various diseases and personal medical conditions, providing a valuable tool for epidemiology and mobile health. PMID:24571349

  4. The National Shipbuilding Research Program. Development of a Quick TBT Analytical Method

    DTIC Science & Technology

    2000-08-16

    Development of a Quick TBT Analytical Method 09/25/2000 Page 3 of 38 Executive Summary Concern about the toxic effect of tributyltin have caused the...paints, developed in the 1960s, contains the organotin tributyltin ( TBT ), which has been proven to cause deformations in oysters and sex changes in...measured response (area counts) for tributyltin in deionized distilled water. Final Report – Development of a Quick TBT Analytical Method 09/25/2000

  5. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Andrews, Joel F.; Sykora, Landon J.; Barik Letostak, Tiasha

    HSP40 family member MRJ (DNAJB6) has been in the spot light for its relevance to Huntington's, Parkinson's diseases, limb-girdle muscular dystrophy, placental development, neural stem cells, cell cycle and malignancies such as breast cancer and melanoma. This gene has two spliced variants coding for 2 distinct proteins with significant homology. However, MRJ(L) (large variant) is predominantly localized to the nucleus whereas MRJ(S) (small variant) is predominantly cytoplasmic. Interestingly MRJ(S) translocates to the nucleus in response to heat shock. The classical heat shock proteins respond to crises (stress) by increasing the number of molecules, usually by transcriptional up-regulation. Our studies implymore » that a quick increase in the molar concentration of MRJ in the nuclear compartment is a novel method by which MRJ responds to stress. We found that MRJ(S) shows NLS (nuclear localization signal) independent nuclear localization in response to heat shock and hypoxia. The specificity of this response is realized due to lack of such response by MRJ(S) when challenged by other stressors, such as some cytokines or UV light. Deletion analysis has allowed us to narrow down on a 20 amino acid stretch at the C-terminal region of MRJ(S) as a potential stress sensing region. Functional studies indicated that constitutive nuclear localization of MRJ(S) promoted attributes of malignancy such as proliferation and invasiveness overall indicating distinct phenotypic characteristics of nuclear MRJ(S).« less

  6. Development of the Brief Romantic Relationship Interaction Coding Scheme (BRRICS)

    PubMed Central

    Humbad, Mikhila N.; Donnellan, M. Brent; Klump, Kelly L.; Burt, S. Alexandra

    2012-01-01

    Although observational studies of romantic relationships are common, many existing coding schemes require considerable amounts of time and resources to implement. The current study presents a new coding scheme, the Brief Romantic Relationship Interaction Coding Scheme (BRRICS), designed to assess various aspects of romantic relationship both quickly and efficiently. The BRRICS consists of four individual coding dimensions assessing positive and negative affect in each member of the dyad, as well as four codes assessing specific components of the dyadic interaction (i.e., positive reciprocity, demand-withdraw pattern, negative reciprocity, and overall satisfaction). Concurrent associations with measures of marital adjustment and conflict were evaluated in a sample of 118 married couples participating in the Michigan State University Twin Registry. Couples were asked to discuss common conflicts in their marriage while being videotaped. Undergraduate coders used the BRRICS to rate these interactions. The BRRICS scales were correlated in expected directions with self-reports of marital adjustment, as well as children’s perception of the severity and frequency of marital conflict. Based on these results, the BRRICS may be an efficient tool for researchers with large samples of observational data who are interested in coding global aspects of the relationship but do not have the resources to use labor intensive schemes. PMID:21875192

  7. Individual Differences in Military Training Environments: Four Areas of Research

    DTIC Science & Technology

    1987-01-30

    training setting. Such factors as ability, skills, experience, intelligence , interests, personal characteristics (e.g., age) and motivation interact...recruits than were Intelligence scores; fast learners retained more and relearned more quickly than slow learners. This suggests that if the goal is to...and Development Center. Gottfredson , G.D., Holland, J.L. and Ogawa, D.K. (1982). Dictionary of Holland occupational codes. Palo Alto, CA: Consulting

  8. Natural Icing Re-Evaluation of the EH-60A Quick Fix Helicopter

    DTIC Science & Technology

    1989-05-01

    INDIVIDUAL 22b. TELEPHONE (Include Area Code) 22c. OFFICE SYMBOL ,!.lIl.,.\\ R I ,VIS (805) 277-2115 , , SAVIF-PR DDForm 1473, JUN 86 Previous editions are...Rc1iiort. -\\I-.FA PI lcit No. 88-06, Artijical and Natural Iking Test. of the I-il- trA )iuck IFix lI ic-opici June 1988. I ttcr. AVSCO(), AISA \\V--S

  9. Environmental Health Monitor: Advanced Development of Temperature Sensor Suite.

    DTIC Science & Technology

    1995-07-30

    systems was implemented using program code existing at Veritay. The software , written in Microsoft® QuickBASIC, facilitated program changes for...currently unforeseen reason re-calibration is needed, this can be readily * accommodated by a straightforward change in the software program---without...unit. A linear relationship between these differences * was obtained using curve fitting software . The ½/-inch globe to 6-inch globe correlation * was

  10. The Top 100. The Fastest Growing Careers for the 21st Century. Revised Edition.

    ERIC Educational Resources Information Center

    1998

    This publication presents 100 careers the U.S. Department of Labor and other sources project as the fastest growing through the year 2006. A shaded bar on the bottom of the title page of each article contains a listing of codes for three commonly used government classification systems. Shaded bars at the bottom of other pages provide quick facts.…

  11. A 21st Century Training Model for Flexible, Quick, and Life-Long Workforce Development

    DTIC Science & Technology

    2016-02-01

    specialty code . Differentiation and tailored training are made possible through modern talent management. 8 When Joslin entered Initial Skills...associated with the IST pipeline, but also identified five overarching themes:  Talent Management,  Asynchronous Training,  Modularity (coaching...augmented reality Figure 1: The combination of modern recruitment, talent management, and modular training both in the school house and online speed

  12. Development and evaluation of a Naïve Bayesian model for coding causation of workers’ compensation claims☆

    PubMed Central

    Bertke, S. J.; Meyers, A. R.; Wurzelbacher, S. J.; Bell, J.; Lampl, M. L.; Robins, D.

    2015-01-01

    Introduction Tracking and trending rates of injuries and illnesses classified as musculoskeletal disorders caused by ergonomic risk factors such as overexertion and repetitive motion (MSDs) and slips, trips, or falls (STFs) in different industry sectors is of high interest to many researchers. Unfortunately, identifying the cause of injuries and illnesses in large datasets such as workers’ compensation systems often requires reading and coding the free form accident text narrative for potentially millions of records. Method To alleviate the need for manual coding, this paper describes and evaluates a computer auto-coding algorithm that demonstrated the ability to code millions of claims quickly and accurately by learning from a set of previously manually coded claims. Conclusions The auto-coding program was able to code claims as a musculoskeletal disorders, STF or other with approximately 90% accuracy. Impact on industry The program developed and discussed in this paper provides an accurate and efficient method for identifying the causation of workers’ compensation claims as a STF or MSD in a large database based on the unstructured text narrative and resulting injury diagnoses. The program coded thousands of claims in minutes. The method described in this paper can be used by researchers and practitioners to relieve the manual burden of reading and identifying the causation of claims as a STF or MSD. Furthermore, the method can be easily generalized to code/classify other unstructured text narratives. PMID:23206504

  13. Asthma and Respiratory Foundation NZ child and adolescent asthma guidelines: a quick reference guide.

    PubMed

    Asher, Innes; McNamara, David; Davies, Cheryl; Demetriou, Teresa; Fleming, Theresa; Harwood, Matire; Hetaraka-Stevens, Lorraine; Ingham, Tristram; Kristiansen, John; Reid, Jim; Rickard, Debbie; Ryan, Debbie

    2017-12-01

    The purpose of the New Zealand Child and adolescent asthma guidelines: a quick reference guide is to provide simple, practical, evidence-based recommendations for the diagnosis, assessment and management of asthma in children and adolescents in New Zealand, with the aim of improving outcomes and reducing inequities. The intended users are health professionals responsible for delivering asthma care in the community and hospital emergency department settings, and those responsible for the training of such health professionals.

  14. Aviation System Analysis Capability Quick Response System Report

    NASA Technical Reports Server (NTRS)

    Roberts, Eileen; Villani, James A.; Ritter, Paul

    1998-01-01

    The purpose of this document is to present the additions and modifications made to the Aviation System Analysis Capability (ASAC) Quick Response System (QRS) in FY 1997 in support of the ASAC ORS development effort. This document contains an overview of the project background and scope and defines the QRS. The document also presents an overview of the Logistics Management Institute (LMI) facility that supports the QRS, and it includes a summary of the planned additions to the QRS in FY 1998. The document has five appendices.

  15. Implementation of the high-order schemes QUICK and LECUSSO in the COMMIX-1C Program

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sakai, K.; Sun, J.G.; Sha, W.T.

    Multidimensional analysis computer programs based on the finite volume method, such as COMMIX-1C, have been commonly used to simulate thermal-hydraulic phenomena in engineering systems such as nuclear reactors. In COMMIX-1C, the first-order schemes with respect to both space and time are used. In many situations such as flow recirculations and stratifications with steep gradient of velocity and temperature fields, however, high-order difference schemes are necessary for an accurate prediction of the fields. For these reasons, two second-order finite difference numerical schemes, QUICK (Quadratic Upstream Interpolation for Convective Kinematics) and LECUSSO (Local Exact Consistent Upwind Scheme of Second Order), have beenmore » implemented in the COMMIX-1C computer code. The formulations were derived for general three-dimensional flows with nonuniform grid sizes. Numerical oscillation analyses for QUICK and LECUSSO were performed. To damp the unphysical oscillations which occur in calculations with high-order schemes at high mesh Reynolds numbers, a new FRAM (Filtering Remedy and Methodology) scheme was developed and implemented. To be consistent with the high-order schemes, the pressure equation and the boundary conditions for all the conservation equations were also modified to be of second order. The new capabilities in the code are listed. Test calculations were performed to validate the implementation of the high-order schemes. They include the test of the one-dimensional nonlinear Burgers equation, two-dimensional scalar transport in two impinging streams, von Karmann vortex shedding, shear driven cavity flow, Couette flow, and circular pipe flow. The calculated results were compared with available data; the agreement is good.« less

  16. Low-Latency and Energy-Efficient Data Preservation Mechanism in Low-Duty-Cycle Sensor Networks.

    PubMed

    Jiang, Chan; Li, Tao-Shen; Liang, Jun-Bin; Wu, Heng

    2017-05-06

    Similar to traditional wireless sensor networks (WSN), the nodes only have limited memory and energy in low-duty-cycle sensor networks (LDC-WSN). However, different from WSN, the nodes in LDC-WSN often sleep most of their time to preserve their energies. The sleeping feature causes serious data transmission delay. However, each source node that has sensed data needs to quickly disseminate its data to other nodes in the network for redundant storage. Otherwise, data would be lost due to its source node possibly being destroyed by outer forces in a harsh environment. The quick dissemination requirement produces a contradiction with the sleeping delay in the network. How to quickly disseminate all the source data to all the nodes with limited memory in the network for effective preservation is a challenging issue. In this paper, a low-latency and energy-efficient data preservation mechanism in LDC-WSN is proposed. The mechanism is totally distributed. The data can be disseminated to the network with low latency by using a revised probabilistic broadcasting mechanism, and then stored by the nodes with LT (Luby Transform) codes, which are a famous rateless erasure code. After the process of data dissemination and storage completes, some nodes may die due to being destroyed by outer forces. If a mobile sink enters the network at any time and from any place to collect the data, it can recover all of the source data by visiting a small portion of survived nodes in the network. Theoretical analyses and simulation results show that our mechanism outperforms existing mechanisms in the performances of data dissemination delay and energy efficiency.

  17. New technologies for advanced three-dimensional optimum shape design in aeronautics

    NASA Astrophysics Data System (ADS)

    Dervieux, Alain; Lanteri, Stéphane; Malé, Jean-Michel; Marco, Nathalie; Rostaing-Schmidt, Nicole; Stoufflet, Bruno

    1999-05-01

    The analysis of complex flows around realistic aircraft geometries is becoming more and more predictive. In order to obtain this result, the complexity of flow analysis codes has been constantly increasing, involving more refined fluid models and sophisticated numerical methods. These codes can only run on top computers, exhausting their memory and CPU capabilities. It is, therefore, difficult to introduce best analysis codes in a shape optimization loop: most previous works in the optimum shape design field used only simplified analysis codes. Moreover, as the most popular optimization methods are the gradient-based ones, the more complex the flow solver, the more difficult it is to compute the sensitivity code. However, emerging technologies are contributing to make such an ambitious project, of including a state-of-the-art flow analysis code into an optimisation loop, feasible. Among those technologies, there are three important issues that this paper wishes to address: shape parametrization, automated differentiation and parallel computing. Shape parametrization allows faster optimization by reducing the number of design variable; in this work, it relies on a hierarchical multilevel approach. The sensitivity code can be obtained using automated differentiation. The automated approach is based on software manipulation tools, which allow the differentiation to be quick and the resulting differentiated code to be rather fast and reliable. In addition, the parallel algorithms implemented in this work allow the resulting optimization software to run on increasingly larger geometries. Copyright

  18. Inversion of Zeeman polarization for solar magnetic field diagnostics

    NASA Astrophysics Data System (ADS)

    Derouich, M.

    2017-05-01

    The topic of magnetic field diagnostics with the Zeeman effect is currently vividly discussed. There are some testable inversion codes available to the spectropolarimetry community and their application allowed for a better understanding of the magnetism of the solar atmosphere. In this context, we propose an inversion technique associated with a new numerical code. The inversion procedure is promising and particularly successful for interpreting the Stokes profiles in quick and sufficiently precise way. In our inversion, we fit a part of each Stokes profile around a target wavelength, and then determine the magnetic field as a function of the wavelength which is equivalent to get the magnetic field as a function of the height of line formation. To test the performance of the new numerical code, we employed "hare and hound" approach by comparing an exact solution (called input) with the solution obtained by the code (called output). The precision of the code is also checked by comparing our results to the ones obtained with the HAO MERLIN code. The inversion code has been applied to synthetic Stokes profiles of the Na D1 line available in the literature. We investigated the limitations in recovering the input field in case of noisy data. As an application, we applied our inversion code to the polarization profiles of the Fe Iλ 6302.5 Å observed at IRSOL in Locarno.

  19. TADSim: Discrete Event-based Performance Prediction for Temperature Accelerated Dynamics

    DOE PAGES

    Mniszewski, Susan M.; Junghans, Christoph; Voter, Arthur F.; ...

    2015-04-16

    Next-generation high-performance computing will require more scalable and flexible performance prediction tools to evaluate software--hardware co-design choices relevant to scientific applications and hardware architectures. Here, we present a new class of tools called application simulators—parameterized fast-running proxies of large-scale scientific applications using parallel discrete event simulation. Parameterized choices for the algorithmic method and hardware options provide a rich space for design exploration and allow us to quickly find well-performing software--hardware combinations. We demonstrate our approach with a TADSim simulator that models the temperature-accelerated dynamics (TAD) method, an algorithmically complex and parameter-rich member of the accelerated molecular dynamics (AMD) family ofmore » molecular dynamics methods. The essence of the TAD application is captured without the computational expense and resource usage of the full code. We accomplish this by identifying the time-intensive elements, quantifying algorithm steps in terms of those elements, abstracting them out, and replacing them by the passage of time. We use TADSim to quickly characterize the runtime performance and algorithmic behavior for the otherwise long-running simulation code. We extend TADSim to model algorithm extensions, such as speculative spawning of the compute-bound stages, and predict performance improvements without having to implement such a method. Validation against the actual TAD code shows close agreement for the evolution of an example physical system, a silver surface. Finally, focused parameter scans have allowed us to study algorithm parameter choices over far more scenarios than would be possible with the actual simulation. This has led to interesting performance-related insights and suggested extensions.« less

  20. Measurement Properties of the Brief Michigan Hand Outcomes Questionnaire in Patients With Dupuytren Contracture.

    PubMed

    Wehrli, Martina; Hensler, Stefanie; Schindele, Stephan; Herren, Daniel B; Marks, Miriam

    2016-09-01

    The brief Michigan Hand Outcomes Questionnaire (briefMHQ) was developed as a shorter version of the Michigan Hand Outcomes Questionnaire (MHQ), but its measurement properties have not been investigated in patients with Dupuytren contracture. The objective of the study was to investigate the reliability, validity, responsiveness, and interpretability of the briefMHQ. Fifty-seven patients diagnosed with Dupuytren contracture completed the briefMHQ as well as the full-length MHQ and Quick Disabilities of the Arm, Shoulder, and Hand (QuickDASH) questionnaire at baseline. Two to 14 days after baseline and 1 year after collagenase injection or surgery, patients again filled out the briefMHQ. Reliability was determined using the intraclass correlation coefficient and by calculating internal consistency (Cronbach alpha). Validity was tested by quantifying correlations with the full-length MHQ and QuickDASH. Responsiveness, based on the standardized response mean and the minimally clinically important change, was also determined. The briefMHQ had an intraclass correlation coefficient of 0.87, Cronbach alpha of 0.88, and correlations of r = 0.88 and -0.82 with the original MHQ and QuickDASH, respectively. The standardized response mean was 0.9 and the minimally clinically important change was 7 points. Overall, the briefMHQ demonstrates excellent reliability, good validity, and high responsiveness in patients with Dupuytren contracture. The briefMHQ is an accurate and time-saving tool to evaluate patients with Dupuytren contracture and the effect of a corresponding treatment. Copyright © 2016 American Society for Surgery of the Hand. Published by Elsevier Inc. All rights reserved.

  1. GIS Based System for Post-Earthquake Crisis Managment Using Cellular Network

    NASA Astrophysics Data System (ADS)

    Raeesi, M.; Sadeghi-Niaraki, A.

    2013-09-01

    Earthquakes are among the most destructive natural disasters. Earthquakes happen mainly near the edges of tectonic plates, but they may happen just about anywhere. Earthquakes cannot be predicted. Quick response after disasters, like earthquake, decreases loss of life and costs. Massive earthquakes often cause structures to collapse, trapping victims under dense rubble for long periods of time. After the earthquake and destroyed some areas, several teams are sent to find the location of the destroyed areas. The search and rescue phase usually is maintained for many days. Time reduction for surviving people is very important. A Geographical Information System (GIS) can be used for decreasing response time and management in critical situations. Position estimation in short period of time time is important. This paper proposes a GIS based system for post-earthquake disaster management solution. This system relies on several mobile positioning methods such as cell-ID and TA method, signal strength method, angel of arrival method, time of arrival method and time difference of arrival method. For quick positioning, the system can be helped by any person who has a mobile device. After positioning and specifying the critical points, the points are sent to a central site for managing the procedure of quick response for helping. This solution establishes a quick way to manage the post-earthquake crisis.

  2. Design of a recovery system for a reentry vehicle

    NASA Technical Reports Server (NTRS)

    Von Eckroth, Wulf; Garrard, William L.; Miller, Norman

    1993-01-01

    Engineers are often required to design decelerator systems which are deployed in cross-wind orientations. If the system is not designed to minimize 'line sail', damage to the parachutes could result. A Reentry Vehicle Analysis Code (RVAC) and an accompanying graphics animation software program (DISPLAY) are presented in this paper. These computer codes allow the user to quickly apply the Purvis line sail modeling technique to any vehicle and then observe the relative motion of the vehicle, nose cap, suspension lines, pilot and drogue bags and canopies on a computer screen. Data files are created which allow plots of velocities, spacial positions, and dynamic pressures versus time to be generated. The code is an important tool for the design engineer because it integrates two degrees of freedom (DOF) line sail equations with a three DOF model of the reentry body and jettisoned nose cap to provide an animated output.

  3. Coordinated observations of X-ray bright BL Lacertae objects

    NASA Technical Reports Server (NTRS)

    Urry, C. M.

    1986-01-01

    No new International Ultraviolet Explorer (IUE) observations were scheduled. The work on the spectral extraction routine was continued. The computer code was adapted from the RDAF PDP 11/44 computer to a VAX 11/750, in order that it run more quickly. A chapter on ultraviolet observations of blazars for a book celebrating the scientific accomplishment of IUE was written in colloboration. A copy of the final draft is attached.

  4. Environmental Compliance Assessment for Army Reserves (ECAAR)

    DTIC Science & Technology

    1991-11-01

    The number of environmental laws and regulations has continued to grow in the United States and worldwide, making compliance with these regulations...they became notices of violation. The concept was to combine Code of Federal Regulations and Army environmental regulations, with good management...items or operations to review, and would list a point of contact for that item to help assessors review the questions, or protocols, quickly and easily

  5. A Quick Guide to Education Data Resources. A Tabletop Reference to Selected NCES Web Site Tools. For Librarians, Students, and Parents.

    ERIC Educational Resources Information Center

    National Center for Education Statistics (ED), Washington, DC.

    This leaflet is a guide to data resources on the Internet related to education. The first Web site listed, http://nces.ed.gov/globallocator/, allows the user to search for public and private elementary and secondary schools by name, city, state, or zip code. The second site, "The Students' Classroom," offers information on a range of…

  6. Reinforcement Learning Applications to Combat Identification

    DTIC Science & Technology

    2017-03-01

    Operations and Reports, 1215 Jefferson Davis Highway, Suite 1204, Arlington, VA 22202-4302, and to the Office of Management and Budget, Paperwork...DISTRIBUTION CODE 13. ABSTRACT (maximum 200 words) Crucial to the safe and effective operation of U.S. Navy vessels is the quick and accurate...abilities of a human operator . While this research does focus on a sea-based, naval, application, the findings can also be expanded to DOD-wide

  7. Ion-Transport Design for High-Performance Na+-Based Electrochromics.

    PubMed

    Li, Ran; Li, Kerui; Wang, Gang; Li, Lei; Zhang, Qiangqiang; Yan, Jinhui; Chen, Yao; Zhang, Qinghong; Hou, Chengyi; Li, Yaogang; Wang, Hongzhi

    2018-04-24

    Sodium ion (Na + )-based electrochemical systems have been extensively investigated in batteries and supercapacitors and also can be quality candidates for electrochromic (EC) devices. However, poor diffusion kinetics and severe EC performance degradation occur during the intercalation/deintercalation processes because the ionic radii of Na + are larger than those of conventional intercalation ions. Here, through intentional design of ion-transport channels in metal-organic frameworks (MOFs), Na + serves as an efficient intercalation ion for incorporation into a nanostructured electrode with a high diffusion coefficient of approximately 10 -8 cm 2 s -1 . As a result, the well-designed MOF-based EC device demonstrates desirable Na + EC performance, including fast switching speed, multicolor switching, and high stability. A smart "quick response code" display is fabricated using a mask-free laser writing method for application in the "Internet of Things". In addition, the concept of ion transport pathway design can be widely adopted for fabricating high-performance ion intercalation materials and devices for consumer electronics.

  8. An Analysis of Scalable GPU-Based Ray-Guided Volume Rendering

    PubMed Central

    Fogal, Thomas; Schiewe, Alexander; Krüger, Jens

    2014-01-01

    Volume rendering continues to be a critical method for analyzing large-scale scalar fields, in disciplines as diverse as biomedical engineering and computational fluid dynamics. Commodity desktop hardware has struggled to keep pace with data size increases, challenging modern visualization software to deliver responsive interactions for O(N3) algorithms such as volume rendering. We target the data type common in these domains: regularly-structured data. In this work, we demonstrate that the major limitation of most volume rendering approaches is their inability to switch the data sampling rate (and thus data size) quickly. Using a volume renderer inspired by recent work, we demonstrate that the actual amount of visualizable data for a scene is typically bound considerably lower than the memory available on a commodity GPU. Our instrumented renderer is used to investigate design decisions typically swept under the rug in volume rendering literature. The renderer is freely available, with binaries for all major platforms as well as full source code, to encourage reproduction and comparison with future research. PMID:25506079

  9. Correcting names of bacteria deposited in National Microbial Repositories: an analysed sequence data necessary for taxonomic re-categorization of misclassified bacteria-ONE example, genus Lysinibacillus.

    PubMed

    Rekadwad, Bhagwan N; Gonzalez, Juan M

    2017-08-01

    A report on 16S rRNA gene sequence re-analysis and digitalization is presented using Lysinibacillus species (one example) deposited in National Microbial Repositories in India. Lysinibacillus species 16S rRNA gene sequences were digitalized to provide quick response (QR) codes, Chaose Game Representation (CGR) and Frequency of Chaose Game Representation (FCGR). GC percentage, phylogenetic analysis, and principal component analysis (PCA) are tools used for the differentiation and reclassification of the strains under investigation. The seven reasons supporting the statements made by us as misclassified Lysinibacillus species deposited in National Microbial Depositories are given in this paper. Based on seven reasons, bacteria deposited in National Microbial Repositories such as Lysinibacillus and many other needs reanalyses for their exact identity. Leaves of identity with type strains of related species shows difference 2 to 8 % suggesting that reclassification is needed to correctly assign species names to the analyzed Lysinibacillus strains available in National Microbial Repositories.

  10. Do students with and without lexical retrieval weaknesses respond differently to instruction?

    PubMed

    Allor, J H; Fuchs, D; Mathes, P G

    2001-01-01

    Deficits in phonological processing are theorized to be responsible for at least some reading disabilities. A considerable amount of research demonstrates that many students can be taught one of these phonological processes-phonemic awareness. However, not all students have responded favorably to this instruction. Research has suggested that these nonresponders may be unable to retrieve phonological codes quickly from long-term memory. The purpose of this study was to examine whether such a deficiency, which we refer to as lexical retrieval weakness, blunts the effectiveness of combined phonemic awareness and decoding training. To this end, we compared the effectiveness of phonemic awareness and decoding training for students with and without severe lexical retrieval weaknesses. All students in both groups demonstrated poor phonemic awareness. The results suggested that students with relatively strong lexical retrieval skill responded more favorably to beginning reading instruction than did students with weak lexical retrieval skill. In other words, lexical retrieval weakness may influence reading development independently of the effects of phonemic awareness. Implications for instruction are discussed.

  11. Harsh childhood environmental characteristics predict exploitation and retaliation in humans

    PubMed Central

    McCullough, Michael E.; Pedersen, Eric J.; Schroder, Jaclyn M.; Tabak, Benjamin A.; Carver, Charles S.

    2013-01-01

    Across and within societies, people vary in their propensities towards exploitative and retaliatory defection in potentially cooperative interaction. We hypothesized that this variation reflects adaptive responses to variation in cues during childhood that life will be harsh, unstable and short—cues that probabilistically indicate that it is in one's fitness interests to exploit co-operators and to retaliate quickly against defectors. Here, we show that childhood exposure to family neglect, conflict and violence, and to neighbourhood crime, were positively associated for men (but not women) with exploitation of an interaction partner and retaliatory defection after that partner began to defect. The associations between childhood environment and both forms of defection for men appeared to be mediated by participants' endorsement of a ‘code of honour’. These results suggest that individual differences in mutual benefit cooperation are not merely due to genetic noise, random developmental variation or the operation of domain-general cultural learning mechanisms, but rather, might reflect the adaptive calibration of social strategies to local social–ecological conditions. PMID:23118435

  12. Testing sensory evidence against mnemonic templates

    PubMed Central

    Myers, Nicholas E; Rohenkohl, Gustavo; Wyart, Valentin; Woolrich, Mark W; Nobre, Anna C; Stokes, Mark G

    2015-01-01

    Most perceptual decisions require comparisons between current input and an internal template. Classic studies propose that templates are encoded in sustained activity of sensory neurons. However, stimulus encoding is itself dynamic, tracing a complex trajectory through activity space. Which part of this trajectory is pre-activated to reflect the template? Here we recorded magneto- and electroencephalography during a visual target-detection task, and used pattern analyses to decode template, stimulus, and decision-variable representation. Our findings ran counter to the dominant model of sustained pre-activation. Instead, template information emerged transiently around stimulus onset and quickly subsided. Cross-generalization between stimulus and template coding, indicating a shared neural representation, occurred only briefly. Our results are compatible with the proposal that template representation relies on a matched filter, transforming input into task-appropriate output. This proposal was consistent with a signed difference response at the perceptual decision stage, which can be explained by a simple neural model. DOI: http://dx.doi.org/10.7554/eLife.09000.001 PMID:26653854

  13. Investigation of HZETRN 2010 as a Tool for Single Event Effect Qualification of Avionics Systems

    NASA Technical Reports Server (NTRS)

    Rojdev, Kristina; Koontz, Steve; Atwell, William; Boeder, Paul

    2014-01-01

    NASA's future missions are focused on long-duration deep space missions for human exploration which offers no options for a quick emergency return to Earth. The combination of long mission duration with no quick emergency return option leads to unprecedented spacecraft system safety and reliability requirements. It is important that spacecraft avionics systems for human deep space missions are not susceptible to Single Event Effect (SEE) failures caused by space radiation (primarily the continuous galactic cosmic ray background and the occasional solar particle event) interactions with electronic components and systems. SEE effects are typically managed during the design, development, and test (DD&T) phase of spacecraft development by using heritage hardware (if possible) and through extensive component level testing, followed by system level failure analysis tasks that are both time consuming and costly. The ultimate product of the SEE DD&T program is a prediction of spacecraft avionics reliability in the flight environment produced using various nuclear reaction and transport codes in combination with the component and subsystem level radiation test data. Previous work by Koontz, et al.1 utilized FLUKA, a Monte Carlo nuclear reaction and transport code, to calculate SEE and single event upset (SEU) rates. This code was then validated against in-flight data for a variety of spacecraft and space flight environments. However, FLUKA has a long run-time (on the order of days). CREME962, an easy to use deterministic code offering short run times, was also compared with FLUKA predictions and in-flight data. CREME96, though fast and easy to use, has not been updated in several years and underestimates secondary particle shower effects in spacecraft structural shielding mass. Thus, this paper will investigate the use of HZETRN 20103, a fast and easy to use deterministic transport code, similar to CREME96, that was developed at NASA Langley Research Center primarily for flight crew ionizing radiation dose assessments. HZETRN 2010 includes updates to address secondary particle shower effects more accurately, and might be used as another tool to verify spacecraft avionics system reliability in space flight SEE environments.

  14. Geoethics As a Key Component to an Undergraduate Capstone Experience

    NASA Astrophysics Data System (ADS)

    Geissman, J. W.; McFadden, L. D.

    2014-12-01

    We have taught a required, senior, capstone course, with a focus on geoscience communication, for almost 35 years. While both of us were at the University of New Mexico, we alternated responsibility for teaching this course. The first author continues to teach a similar course at the University of Texas at Dallas. As the course has evolved and new approaches taken, we have incorporated more and more subject matter related to ethics in science and in particular the geological sciences. Our experiences indicate that (1) students are typically enthralled by and curious about the subject, (2) students have received little if any exposure to the subject in any form of formal classroom environment, and (3) students have personally experienced situations or have learned of situations from their peers that have left them in an uncomfortable position and left them questioning the appropriateness of the actions witnessed. We typically introduce the subject of GeoEthics by drawing students' attention to the many Codes of Ethics or Professional Conduct assembled by Geoscience societies. Many students are quick to volunteer their experiences related to specific topics. For example, the statement in the Geological Society of America Code of Conduct, "Geoscientists should treat associates with respect, regardless of the level of their formal education, encourage them, learn with them, share ideas honestly, and give credit for their contributions" often incites lively discussion and reveals repeated behavior by some individuals.

  15. Supporting creativity and appreciation of uncertainty in exploring geo-coded public health data.

    PubMed

    Thew, S L; Sutcliffe, A; de Bruijn, O; McNaught, J; Procter, R; Jarvis, Paul; Buchan, I

    2011-01-01

    We present a prototype visualisation tool, ADVISES (Adaptive Visualization for e-Science), designed to support epidemiologists and public health practitioners in exploring geo-coded datasets and generating spatial epidemiological hypotheses. The tool is designed to support creative thinking while providing the means for the user to evaluate the validity of the visualization in terms of statistical uncertainty. We present an overview of the application and the results of an evaluation exploring public health researchers' responses to maps as a new way of viewing familiar data, in particular the use of thematic maps with adjoining descriptive statistics and forest plots to support the generation and evaluation of new hypotheses. A series of qualitative evaluations involved one experienced researcher asking 21 volunteers to interact with the system to perform a series of relatively complex, realistic map-building and exploration tasks, using a 'think aloud' protocol, followed by a semi-structured interview The volunteers were academic epidemiologists and UK National Health Service analysts. All users quickly and confidently created maps, and went on to spend substantial amounts of time exploring and interacting with system, generating hypotheses about their maps. Our findings suggest that the tool is able to support creativity and statistical appreciation among public health professionals and epidemiologists building thematic maps. Software such as this, introduced appropriately, could increase the capability of existing personnel for generating public health intelligence.

  16. Evaluation and application of the Baldwin-Lomax turbulence model in two-dimensional, unsteady, compressible boundary layers with and without separation in engine inlets

    NASA Technical Reports Server (NTRS)

    Sakowski, Barbara; Darling, Douglas; Roach, Robert L.; Vandewall, Allan

    1992-01-01

    There is a practical need to model high speed flows that exist in jet engine inlets. The boundary layers that form in these inlets may be turbulent or laminar and either separated or attached. Also, unsteady supersonic inlets may be subject to frequent changes in operating conditions. Some changes in the operating conditions of the inlets may include varying the inlet geometry, bleeds and bypasses, and rotating or translating the centerbody. In addition, the inlet may be either started or unstarted. Therefore, a CFD code, used to model these inlets, may have to run for several different cases. Also, since the flow conditions through an unsteady inlet may be continually fluctuating, the CFD code which models these flows may have to be run over many time steps. Therefore, it would be beneficial that the code run quickly. Many turbulence models, however, are cumbersome to implement and require a lot of computer time to run, since they add to the number of differential equations to be solved to model a flow. The Baldwin-Lomax turbulence model is a popular model. It is an algebraic, eddy viscosity model. The Baldwin-Lomax model is used in many CFD codes because it is quick and easy to implement. In this paper, we will discuss implementing the Baldwin-Lomax turbulence model for both steady and unsteady compressible flows. In addition, these flows may be either separated or attached. In order to apply this turbulence model to flows which may be subjected to these conditions, certain modifications should be made to the original Baldwin-Lomax model. We will discuss these modifications and determine whether the Baldwin-Lomax model is a viable turbulence model that produces reasonably accurate results for high speed flows that can be found in engine inlets.

  17. Task representation in individual and joint settings

    PubMed Central

    Prinz, Wolfgang

    2015-01-01

    This paper outlines a framework for task representation and discusses applications to interference tasks in individual and joint settings. The framework is derived from the Theory of Event Coding (TEC). This theory regards task sets as transient assemblies of event codes in which stimulus and response codes interact and shape each other in particular ways. On the one hand, stimulus and response codes compete with each other within their respective subsets (horizontal interactions). On the other hand, stimulus and response code cooperate with each other (vertical interactions). Code interactions instantiating competition and cooperation apply to two time scales: on-line performance (i.e., doing the task) and off-line implementation (i.e., setting the task). Interference arises when stimulus and response codes overlap in features that are irrelevant for stimulus identification, but relevant for response selection. To resolve this dilemma, the feature profiles of event codes may become restructured in various ways. The framework is applied to three kinds of interference paradigms. Special emphasis is given to joint settings where tasks are shared between two participants. Major conclusions derived from these applications include: (1) Response competition is the chief driver of interference. Likewise, different modes of response competition give rise to different patterns of interference; (2) The type of features in which stimulus and response codes overlap is also a crucial factor. Different types of such features give likewise rise to different patterns of interference; and (3) Task sets for joint settings conflate intraindividual conflicts between responses (what), with interindividual conflicts between responding agents (whom). Features of response codes may, therefore, not only address responses, but also responding agents (both physically and socially). PMID:26029085

  18. Easy Web Interfaces to IDL Code for NSTX Data Analysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    W.M. Davis

    Reusing code is a well-known Software Engineering practice to substantially increase the efficiency of code production, as well as to reduce errors and debugging time. A variety of "Web Tools" for the analysis and display of raw and analyzed physics data are in use on NSTX [1], and new ones can be produced quickly from existing IDL [2] code. A Web Tool with only a few inputs, and which calls an IDL routine written in the proper style, can be created in less than an hour; more typical Web Tools with dozens of inputs, and the need for some adaptationmore » of existing IDL code, can be working in a day or so. Efficiency is also increased for users of Web Tools because o f the familiar interface of the web browser, and not needing X-windows, accounts, passwords, etc. Web Tools were adapted for use by PPPL physicists accessing EAST data stored in MDSplus with only a few man-weeks of effort; adapting to additional sites should now be even easier. An overview of Web Tools in use on NSTX, and a list of the most useful features, is also presented.« less

  19. Cloud-based design of high average power traveling wave linacs

    NASA Astrophysics Data System (ADS)

    Kutsaev, S. V.; Eidelman, Y.; Bruhwiler, D. L.; Moeller, P.; Nagler, R.; Barbe Welzel, J.

    2017-12-01

    The design of industrial high average power traveling wave linacs must accurately consider some specific effects. For example, acceleration of high current beam reduces power flow in the accelerating waveguide. Space charge may influence the stability of longitudinal or transverse beam dynamics. Accurate treatment of beam loading is central to the design of high-power TW accelerators, and it is especially difficult to model in the meter-scale region where the electrons are nonrelativistic. Currently, there are two types of available codes: tracking codes (e.g. PARMELA or ASTRA) that cannot solve self-consistent problems, and particle-in-cell codes (e.g. Magic 3D or CST Particle Studio) that can model the physics correctly but are very time-consuming and resource-demanding. Hellweg is a special tool for quick and accurate electron dynamics simulation in traveling wave accelerating structures. The underlying theory of this software is based on the differential equations of motion. The effects considered in this code include beam loading, space charge forces, and external magnetic fields. We present the current capabilities of the code, provide benchmarking results, and discuss future plans. We also describe the browser-based GUI for executing Hellweg in the cloud.

  20. Piloting a Collaborative Web-Based System for Testing ICD-11.

    PubMed

    Donada, Marc; Kostanjsek, Nenad; Della Mea, Vincenzo; Celik, Can; Jakob, Robert

    2017-01-01

    The 11th revision of the International Classification of Diseases (ICD-11), for the first time in ICD history, deployed web-based collaboration of experts and ICT tools. To ensure that ICD-11 is working well, it needs to be systematically field tested in different settings, across the world. This will be done by means of a number of experiments. In order to support its implementation, a web-based system (ICDfit) has been designed and developed. The present paper illustrates the current prototype of the system and its technical testing. the system has been designed according to WHO requirements, and implemented using PHP and MySQL. Then, a preliminary technical test has been designed and run in January 2016, involving 8 users. They had to carry out double coding, that is, coding case summaries with both ICD-10 and ICD-11, and answering quick questions on the coding difficulty. the 8 users coded 632 cases each, spending an average of 163 seconds per case. While we found an issue in the mechanism used to record coding times, no further issues were found. the proposed system seems to be technically adequate for supporting future ICD-11 testing.

  1. The primitive code and repeats of base oligomers as the primordial protein-encoding sequence.

    PubMed Central

    Ohno, S; Epplen, J T

    1983-01-01

    Even if the prebiotic self-replication of nucleic acids and the subsequent emergence of primitive, enzyme-independent tRNAs are accepted as plausible, the origin of life by spontaneous generation still appears improbable. This is because the just-emerged primitive translational machinery had to cope with base sequences that were not preselected for their coding potentials. Particularly if the primitive mitochondria-like code with four chain-terminating base triplets preceded the universal code, the translation of long, randomly generated, base sequences at this critical stage would have merely resulted in the production of short oligopeptides instead of long polypeptide chains. We present the base sequence of a mouse transcript containing tetranucleotide repeats conserved during evolution. Even if translated in accordance with the primitive mitochondria-like code, this transcript in its three reading frames can yield 245-, 246-, and 251-residue-long tetrapeptidic periodical polypeptides that are already acquiring longer periodicities. We contend that the first set of base sequences translated at the beginning of life were such oligonucleotide repeats. By quickly acquiring longer periodicities, their products must have soon gained characteristic secondary structures--alpha-helical or beta-sheet or both. PMID:6574491

  2. Modelling Per Capita Water Demand Change to Support System Planning

    NASA Astrophysics Data System (ADS)

    Garcia, M. E.; Islam, S.

    2016-12-01

    Water utilities have a number of levers to influence customer water usage. These include levers to proactively slow demand growth over time such as building and landscape codes as well as levers to decrease demands quickly in response to water stress including price increases, education campaigns, water restrictions, and incentive programs. Even actions aimed at short term reductions can result in long term water usage declines when substantial changes are made in water efficiency, as in incentives for fixture replacement or turf removal, or usage patterns such as permanent lawn watering restrictions. Demand change is therefore linked to hydrological conditions and to the effects of past management decisions - both typically included in water supply planning models. Yet, demand is typically incorporated exogenously using scenarios or endogenously using only price, though utilities also use rules and incentives issued in response to water stress and codes specifying standards for new construction to influence water usage. Explicitly including these policy levers in planning models enables concurrent testing of infrastructure and policy strategies and illuminates interactions between the two. The City of Las Vegas is used as a case study to develop and demonstrate this modeling approach. First, a statistical analysis of system data was employed to rule out alternate hypotheses of per capita demand decrease such as changes in population density and economic structure. Next, four demand sub-models were developed including one baseline model in which demand is a function of only price. The sub-models were then calibrated and tested using monthly data from 1997 to 2012. Finally, the best performing sub-model was integrated with a full supply and demand model. The results highlight the importance of both modeling water demand dynamics endogenously and taking a broader view of the variables influencing demand change.

  3. Evaluating Varied Label Designs for Use with Medical Devices: Optimized Labels Outperform Existing Labels in the Correct Selection of Devices and Time to Select.

    PubMed

    Bix, Laura; Seo, Do Chan; Ladoni, Moslem; Brunk, Eric; Becker, Mark W

    2016-01-01

    Effective standardization of medical device labels requires objective study of varied designs. Insufficient empirical evidence exists regarding how practitioners utilize and view labeling. Measure the effect of graphic elements (boxing information, grouping information, symbol use and color-coding) to optimize a label for comparison with those typical of commercial medical devices. Participants viewed 54 trials on a computer screen. Trials were comprised of two labels that were identical with regard to graphics, but differed in one aspect of information (e.g., one had latex, the other did not). Participants were instructed to select the label along a given criteria (e.g., latex containing) as quickly as possible. Dependent variables were binary (correct selection) and continuous (time to correct selection). Eighty-nine healthcare professionals were recruited at Association of Surgical Technologists (AST) conferences, and using a targeted e-mail of AST members. Symbol presence, color coding and grouping critical pieces of information all significantly improved selection rates and sped time to correct selection (α = 0.05). Conversely, when critical information was graphically boxed, probability of correct selection and time to selection were impaired (α = 0.05). Subsequently, responses from trials containing optimal treatments (color coded, critical information grouped with symbols) were compared to two labels created based on a review of those commercially available. Optimal labels yielded a significant positive benefit regarding the probability of correct choice ((P<0.0001) LSM; UCL, LCL: 97.3%; 98.4%, 95.5%)), as compared to the two labels we created based on commercial designs (92.0%; 94.7%, 87.9% and 89.8%; 93.0%, 85.3%) and time to selection. Our study provides data regarding design factors, namely: color coding, symbol use and grouping of critical information that can be used to significantly enhance the performance of medical device labels.

  4. Clinical code set engineering for reusing EHR data for research: A review.

    PubMed

    Williams, Richard; Kontopantelis, Evangelos; Buchan, Iain; Peek, Niels

    2017-06-01

    The construction of reliable, reusable clinical code sets is essential when re-using Electronic Health Record (EHR) data for research. Yet code set definitions are rarely transparent and their sharing is almost non-existent. There is a lack of methodological standards for the management (construction, sharing, revision and reuse) of clinical code sets which needs to be addressed to ensure the reliability and credibility of studies which use code sets. To review methodological literature on the management of sets of clinical codes used in research on clinical databases and to provide a list of best practice recommendations for future studies and software tools. We performed an exhaustive search for methodological papers about clinical code set engineering for re-using EHR data in research. This was supplemented with papers identified by snowball sampling. In addition, a list of e-phenotyping systems was constructed by merging references from several systematic reviews on this topic, and the processes adopted by those systems for code set management was reviewed. Thirty methodological papers were reviewed. Common approaches included: creating an initial list of synonyms for the condition of interest (n=20); making use of the hierarchical nature of coding terminologies during searching (n=23); reviewing sets with clinician input (n=20); and reusing and updating an existing code set (n=20). Several open source software tools (n=3) were discovered. There is a need for software tools that enable users to easily and quickly create, revise, extend, review and share code sets and we provide a list of recommendations for their design and implementation. Research re-using EHR data could be improved through the further development, more widespread use and routine reporting of the methods by which clinical codes were selected. Copyright © 2017 The Author(s). Published by Elsevier Inc. All rights reserved.

  5. Current and anticipated uses of the thermal hydraulics codes at the NRC

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Caruso, R.

    1997-07-01

    The focus of Thermal-Hydraulic computer code usage in nuclear regulatory organizations has undergone a considerable shift since the codes were originally conceived. Less work is being done in the area of {open_quotes}Design Basis Accidents,{close_quotes}, and much more emphasis is being placed on analysis of operational events, probabalistic risk/safety assessment, and maintenance practices. All of these areas need support from Thermal-Hydraulic computer codes to model the behavior of plant fluid systems, and they all need the ability to perform large numbers of analyses quickly. It is therefore important for the T/H codes of the future to be able to support thesemore » needs, by providing robust, easy-to-use, tools that produce easy-to understand results for a wider community of nuclear professionals. These tools need to take advantage of the great advances that have occurred recently in computer software, by providing users with graphical user interfaces for both input and output. In addition, reduced costs of computer memory and other hardware have removed the need for excessively complex data structures and numerical schemes, which make the codes more difficult and expensive to modify, maintain, and debug, and which increase problem run-times. Future versions of the T/H codes should also be structured in a modular fashion, to allow for the easy incorporation of new correlations, models, or features, and to simplify maintenance and testing. Finally, it is important that future T/H code developers work closely with the code user community, to ensure that the code meet the needs of those users.« less

  6. Enhanced anti-counterfeiting measures for additive manufacturing: coupling lanthanide nanomaterial chemical signatures with blockchain technology

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kennedy, Zachary C.; Stephenson, David E.; Christ, Josef F.

    The significant rise of additive manufacturing (AM) in recent years is in part due to the open sourced nature of the printing processes and reduced cost and capital barriers relative to traditional manufacturing. However, this democratization of manufacturing spurs an increased demand for producers and end-users to verify the authenticity and quality of individual parts. To this end, we introduce an anti-counterfeiting method composed of first embedding engineered nanomaterials into features of a 3D-printed part followed by non-destructive interrogation of these features to quantify a chemical signature profile. The part specific chemical signature data is then linked to a securitized,more » distributed, and time-stamped blockchain ledger entry. To demonstrate the utility of this approach, lanthanide-aspartic acid nanoscale coordination polymers (Ln3+- Asp NCs) / poly(lactic) acid (PLA) composites were formulated and transformed into a filament feedstock for fused deposition modeling (FDM) 3D printing. In the present case, a quick-response (QR) code containing the doped Ln3+-Asp NCs was printed using a dual-extruder FDM printer into pure PLA parts. The QR code provides a searchable reference to an Ethereum-based blockchain entry. The QR code physical features also serve as defined areas to probe the signatures arising from the embedded Ln3+-Asp NCs. Visible fluorescence emission with UV-excitation was quantified in terms of color using a smartphone camera and incorporated into blockchain entries. Ultimately, linking unique chemical signature data to blockchain databases is anticipated to make the costs of counterfeiting AM materials significantly more prohibitive and transactions between those in the supply chain more trustworthy.« less

  7. Transcriptomic analysis reveals metabolic switches and surface remodeling as key processes for stage transition in Trypanosoma cruzi

    PubMed Central

    Greif, Gonzalo; Rodriguez, Matias; Alvarez-Valin, Fernando

    2017-01-01

    American trypanosomiasis is a chronic and endemic disease which affects millions of people. Trypanosoma cruzi, its causative agent, has a life cycle that involves complex morphological and functional transitions, as well as a variety of environmental conditions. This requires a tight regulation of gene expression, which is achieved mainly by post-transcriptional regulation. In this work we conducted an RNAseq analysis of the three major life cycle stages of T. cruzi: amastigotes, epimastigotes and trypomastigotes. This analysis allowed us to delineate specific transcriptomic profiling for each stage, and also to identify those biological processes of major relevance in each state. Stage specific expression profiling evidenced the plasticity of T. cruzi to adapt quickly to different conditions, with particular focus on membrane remodeling and metabolic shifts along the life cycle. Epimastigotes, which replicate in the gut of insect vectors, showed higher expression of genes related to energy metabolism, mainly Krebs cycle, respiratory chain and oxidative phosphorylation related genes, and anabolism related genes associated to nucleotide and steroid biosynthesis; also, a general down-regulation of surface glycoprotein coding genes was seen at this stage. Trypomastigotes, living extracellularly in the bloodstream of mammals, express a plethora of surface proteins and signaling genes involved in invasion and evasion of immune response. Amastigotes mostly express membrane transporters and genes involved in regulation of cell cycle, and also express a specific subset of surface glycoprotein coding genes. In addition, these results allowed us to improve the annotation of the Dm28c genome, identifying new ORFs and set the stage for construction of networks of co-expression, which can give clues about coded proteins of unknown functions. PMID:28286708

  8. Operation of the helicopter antenna radiation prediction code

    NASA Technical Reports Server (NTRS)

    Braeden, E. W.; Klevenow, F. T.; Newman, E. H.; Rojas, R. G.; Sampath, K. S.; Scheik, J. T.; Shamansky, H. T.

    1993-01-01

    HARP is a front end as well as a back end for the AMC and NEWAIR computer codes. These codes use the Method of Moments (MM) and the Uniform Geometrical Theory of Diffraction (UTD), respectively, to calculate the electromagnetic radiation patterns for antennas on aircraft. The major difficulty in using these codes is in the creation of proper input files for particular aircraft and in verifying that these files are, in fact, what is intended. HARP creates these input files in a consistent manner and allows the user to verify them for correctness using sophisticated 2 and 3D graphics. After antenna field patterns are calculated using either MM or UTD, HARP can display the results on the user's screen or provide hardcopy output. Because the process of collecting data, building the 3D models, and obtaining the calculated field patterns was completely automated by HARP, the researcher's productivity can be many times what it could be if these operations had to be done by hand. A complete, step by step, guide is provided so that the researcher can quickly learn to make use of all the capabilities of HARP.

  9. ARES: automated response function code. Users manual. [HPGAM and LSQVM

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Maung, T.; Reynolds, G.M.

    This ARES user's manual provides detailed instructions for a general understanding of the Automated Response Function Code and gives step by step instructions for using the complete code package on a HP-1000 system. This code is designed to calculate response functions of NaI gamma-ray detectors, with cylindrical or rectangular geometries.

  10. Quick Vegas: Improving Performance of TCP Vegas for High Bandwidth-Delay Product Networks

    NASA Astrophysics Data System (ADS)

    Chan, Yi-Cheng; Lin, Chia-Liang; Ho, Cheng-Yuan

    An important issue in designing a TCP congestion control algorithm is that it should allow the protocol to quickly adjust the end-to-end communication rate to the bandwidth on the bottleneck link. However, the TCP congestion control may function poorly in high bandwidth-delay product networks because of its slow response with large congestion windows. In this paper, we propose an enhanced version of TCP Vegas called Quick Vegas, in which we present an efficient congestion window control algorithm for a TCP source. Our algorithm improves the slow-start and congestion avoidance techniques of original Vegas. Simulation results show that Quick Vegas significantly improves the performance of connections as well as remaining fair when the bandwidth-delay product increases.

  11. A color-coded vision scheme for robotics

    NASA Technical Reports Server (NTRS)

    Johnson, Kelley Tina

    1991-01-01

    Most vision systems for robotic applications rely entirely on the extraction of information from gray-level images. Humans, however, regularly depend on color to discriminate between objects. Therefore, the inclusion of color in a robot vision system seems a natural extension of the existing gray-level capabilities. A method for robot object recognition using a color-coding classification scheme is discussed. The scheme is based on an algebraic system in which a two-dimensional color image is represented as a polynomial of two variables. The system is then used to find the color contour of objects. In a controlled environment, such as that of the in-orbit space station, a particular class of objects can thus be quickly recognized by its color.

  12. Introducing a New Software for Geodetic Analysis

    NASA Astrophysics Data System (ADS)

    Hjelle, Geir Arne; Dähnn, Michael; Fausk, Ingrid; Kirkvik, Ann-Silje; Mysen, Eirik

    2017-04-01

    At the Norwegian Mapping Authority, we are currently developing Where, a new software for geodetic analysis. Where is built on our experiences with the Geosat software, and will be able to analyse and combine data from VLBI, SLR, GNSS and DORIS. The software is mainly written in Python which has proved very fruitful. The code is quick to write and the architecture is easily extendable and maintainable, while at the same time taking advantage of well-tested code like the SOFA and IERS libraries. This presentation will show some of the current capabilities of Where, including benchmarks against other software packages, and outline our plans for further progress. In addition we will report on some investigations we have done experimenting with alternative weighting strategies for VLBI.

  13. Cellular stress stimulates nuclear localization signal (NLS) independent nuclear transport of MRJ

    PubMed Central

    Andrews, Joel F.; Sykora, Landon J.; Barik-Letostak, Tiasha; Menezes, Mitchell E.; Mitra, Aparna; Barik, Sailen; Shevde, Lalita A.; Samant, Rajeev S.

    2012-01-01

    HSP40 family member MRJ (DNAJB6) has been in the spot light for its relevance to Huntington’s, Parkinson’s diseases, limb-girdle muscular dystrophy, placental development, neural stem cells, cell cycle and malignancies such as breast cancer and melanoma. This gene has two spliced variants coding for 2 distinct proteins with significant homology. However, MRJ(L) (large variant) is predominantly localized to the nucleus whereas MRJ(S) (small variant) is predominantly cytoplasmic. Interestingly MRJ(S) translocates to the nucleus in response to heat shock. The classical heat shock proteins respond to crises (stress) by increasing the number of molecules, usually by transcriptional up-regulation. Our studies imply that a quick increase in the molar concentration of MRJ in the nuclear compartment is a novel method by which MRJ responds to stress. We found that MRJ(S) shows NLS (nuclear localization signal) independent nuclear localization in response to heat shock and hypoxia. The specificity of this response is realized due to lack of such response by MRJ(S) when challenged by other stressors, such as some cytokines or UV light. Deletion analysis has allowed us to narrow down on a 20 amino acid stretch at the C-terminal region of MRJ(S) as a potential stress sensing region. Functional studies indicated that constitutive nuclear localization of MRJ(S) promoted attributes of malignancy such as proliferation and invasiveness overall indicating distinct phenotypic characteristics of nuclear MRJ(S). PMID:22504047

  14. NeoAnalysis: a Python-based toolbox for quick electrophysiological data processing and analysis.

    PubMed

    Zhang, Bo; Dai, Ji; Zhang, Tao

    2017-11-13

    In a typical electrophysiological experiment, especially one that includes studying animal behavior, the data collected normally contain spikes, local field potentials, behavioral responses and other associated data. In order to obtain informative results, the data must be analyzed simultaneously with the experimental settings. However, most open-source toolboxes currently available for data analysis were developed to handle only a portion of the data and did not take into account the sorting of experimental conditions. Additionally, these toolboxes require that the input data be in a specific format, which can be inconvenient to users. Therefore, the development of a highly integrated toolbox that can process multiple types of data regardless of input data format and perform basic analysis for general electrophysiological experiments is incredibly useful. Here, we report the development of a Python based open-source toolbox, referred to as NeoAnalysis, to be used for quick electrophysiological data processing and analysis. The toolbox can import data from different data acquisition systems regardless of their formats and automatically combine different types of data into a single file with a standardized format. In cases where additional spike sorting is needed, NeoAnalysis provides a module to perform efficient offline sorting with a user-friendly interface. Then, NeoAnalysis can perform regular analog signal processing, spike train, and local field potentials analysis, behavioral response (e.g. saccade) detection and extraction, with several options available for data plotting and statistics. Particularly, it can automatically generate sorted results without requiring users to manually sort data beforehand. In addition, NeoAnalysis can organize all of the relevant data into an informative table on a trial-by-trial basis for data visualization. Finally, NeoAnalysis supports analysis at the population level. With the multitude of general-purpose functions provided by NeoAnalysis, users can easily obtain publication-quality figures without writing complex codes. NeoAnalysis is a powerful and valuable toolbox for users doing electrophysiological experiments.

  15. Does cardiac catheterization laboratory activation by electrocardiography machine auto-interpretation reduce door-to-balloon time?

    PubMed

    Min, Mun Ki; Ryu, Ji Ho; Kim, Yong In; Park, Maeng Real; Park, Yong Myeon; Park, Sung Wook; Yeom, Seok Ran; Han, Sang Kyoon; Kim, Yang Weon

    2014-11-01

    In an attempt to begin ST-segment elevation myocardial infarction (STEMI) treatment more quickly (referred to as door-to-balloon [DTB] time) by minimizing preventable delays in electrocardiogram (ECG) interpretation, cardiac catheterization laboratory (CCL) activation was changed from activation by the emergency physician (code heart I) to activation by a single page if the ECG is interpreted as STEMI by the ECG machine (ECG machine auto-interpretation) (code heart II). We sought to determine the impact of ECG machine auto-interpretation on CCL activation. The study period was from June 2010 to May 2012 (from June to November 2011, code heart I; from December 2011 to May 2012, code heart II). All patients aged 18 years or older who were diagnosed with STEMI were evaluated for enrollment. Patients who experienced the code heart system were also included. Door-to-balloon time before and after code heart system were compared with a retrospective chart review. In addition, to determine the appropriateness of the activation, we compared coronary angiography performance rate and percentage of STEMI between code heart I and II. After the code heart system, the mean DTB time was significantly decreased (before, 96.51 ± 65.60 minutes; after, 65.40 ± 26.40 minutes; P = .043). The STEMI diagnosis and the coronary angiography performance rates were significantly lower in the code heart II group than in the code heart I group without difference in DTB time. Cardiac catheterization laboratory activation by ECG machine auto-interpretation does not reduce DTB time and often unnecessarily activates the code heart system compared with emergency physician-initiated activation. This system therefore decreases the appropriateness of CCL activation. Copyright © 2014 Elsevier Inc. All rights reserved.

  16. Greater physician involvement improves coding outcomes in endobronchial ultrasound-guided transbronchial needle aspiration procedures.

    PubMed

    Pillai, Anilkumar; Medford, Andrew R L

    2013-01-01

    Correct coding is essential for accurate reimbursement for clinical activity. Published data confirm that significant aberrations in coding occur, leading to considerable financial inaccuracies especially in interventional procedures such as endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). Previous data reported a 15% coding error for EBUS-TBNA in a U.K. service. We hypothesised that greater physician involvement with coders would reduce EBUS-TBNA coding errors and financial disparity. The study was done as a prospective cohort study in the tertiary EBUS-TBNA service in Bristol. 165 consecutive patients between October 2009 and March 2012 underwent EBUS-TBNA for evaluation of unexplained mediastinal adenopathy on computed tomography. The chief coder was prospectively electronically informed of all procedures and cross-checked on a prospective database and by Trust Informatics. Cost and coding analysis was performed using the 2010-2011 tariffs. All 165 procedures (100%) were coded correctly as verified by Trust Informatics. This compares favourably with the 14.4% coding inaccuracy rate for EBUS-TBNA in a previous U.K. prospective cohort study [odds ratio 201.1 (1.1-357.5), p = 0.006]. Projected income loss was GBP 40,000 per year in the previous study, compared to a GBP 492,195 income here with no coding-attributable loss in revenue. Greater physician engagement with coders prevents coding errors and financial losses which can be significant especially in interventional specialties. The intervention can be as cheap, quick and simple as a prospective email to the coding team with cross-checks by Trust Informatics and against a procedural database. We suggest that all specialties should engage more with their coders using such a simple intervention to prevent revenue losses. Copyright © 2013 S. Karger AG, Basel.

  17. Auditory brainstem response to complex sounds predicts self-reported speech-in-noise performance.

    PubMed

    Anderson, Samira; Parbery-Clark, Alexandra; White-Schwoch, Travis; Kraus, Nina

    2013-02-01

    To compare the ability of the auditory brainstem response to complex sounds (cABR) to predict subjective ratings of speech understanding in noise on the Speech, Spatial, and Qualities of Hearing Scale (SSQ; Gatehouse & Noble, 2004) relative to the predictive ability of the Quick Speech-in-Noise test (QuickSIN; Killion, Niquette, Gudmundsen, Revit, & Banerjee, 2004) and pure-tone hearing thresholds. Participants included 111 middle- to older-age adults (range = 45-78) with audiometric configurations ranging from normal hearing levels to moderate sensorineural hearing loss. In addition to using audiometric testing, the authors also used such evaluation measures as the QuickSIN, the SSQ, and the cABR. Multiple linear regression analysis indicated that the inclusion of brainstem variables in a model with QuickSIN, hearing thresholds, and age accounted for 30% of the variance in the Speech subtest of the SSQ, compared with significantly less variance (19%) when brainstem variables were not included. The authors' results demonstrate the cABR's efficacy for predicting self-reported speech-in-noise perception difficulties. The fact that the cABR predicts more variance in self-reported speech-in-noise (SIN) perception than either the QuickSIN or hearing thresholds indicates that the cABR provides additional insight into an individual's ability to hear in background noise. In addition, the findings underscore the link between the cABR and hearing in noise.

  18. Human anti-HIV IgM detection by the OraQuick ADVANCE® Rapid HIV 1/2 Antibody Test.

    PubMed

    Guillon, Geraldine; Yearwood, Graham; Snipes, Casey; Boschi, Daniel; Reed, Michael R

    2018-01-01

    The Centers for Disease Control and Prevention (CDC) and many public health jurisdictions continue to advocate for the most sensitive rapid HIV test that is available. Currently, the recommendation is to utilize tests that can detect HIV infection biomarkers within 30 days of infection, when initial immune responses are mounted. The infected patient's IgM response is often used to detect acute infection within a 20-25 days window after infection. This requirement applies to lab-based testing with automated analyzers and rapid, point of care (POC) testing used for screening in a non-clinical setting. A recent study has demonstrated that POC tests using a Protein A-based detection system can detect samples with predominantly HIV-1 IgM reactivity (Moshgabadi et al., 2015). The OraQuick ADVANCE ® Rapid HIV-1/2 Antibody Test (OraQuick ADVANCE ®) also uses Protein A as the detection protein in the antibody-binding colloidal gold conjugate, so it is expected that the OraQuick ADVANCE ® Test will also detect samples with predominantly IgM reactivity. This report definitively demonstrates that the OraQuick ADVANCE ® Test can detect IgM antibodies during an acute infection window period of approximately 20-25 days after infection, and is therefore suitable for use in testing environments requiring adherence to current CDC recommendations.

  19. Quantifying medical student clinical experiences via an ICD Code Logging App.

    PubMed

    Rawlins, Fred; Sumpter, Cameron; Sutphin, Dean; Garner, Harold R

    2018-03-01

    The logging of ICD Diagnostic, Procedure and Drug codes is one means of tracking the experience of medical students' clinical rotations. The goal is to create a web-based computer and mobile application to track the progress of trainees, monitor the effectiveness of their training locations and be a means of sampling public health status. We have developed a web-based app in which medical trainees make entries via a simple and quick interface optimized for both mobile devices and personal computers. For each patient interaction, users enter ICD diagnostic, procedure, and drug codes via a hierarchical or search entry interface, as well as patient demographics (age range and gender, but no personal identifiers), and free-text notes. Users and administrators can review and edit input via a series of output interfaces. The user interface and back-end database are provided via dual redundant failover Linux servers. Students master the interface in ten minutes, and thereafter complete entries in less than one minute. Five hundred-forty 3rd year VCOM students each averaged 100 entries in the first four week clinical rotation. Data accumulated in various Appalachian clinics and Central American medical mission trips has demonstrated the public health surveillance utility of the application. PC and mobile apps can be used to collect medical trainee experience in real time or near real-time, quickly, and efficiently. This system has collected 75,596 entries to date, less than 2% of trainees have needed assistance to become proficient, and medical school administrators are using the various summaries to evaluate students and compare different rotation sites. Copyright © 2017. Published by Elsevier B.V.

  20. A PC-based telemetry system for acquiring and reducing data from multiple PCM streams

    NASA Astrophysics Data System (ADS)

    Simms, D. A.; Butterfield, C. P.

    1991-07-01

    The Solar Energy Research Institute's (SERI) Wind Research Program is using Pulse Code Modulation (PCM) Telemetry Data-Acquisition Systems to study horizontal-axis wind turbines. Many PCM systems are combined for use in test installations that require accurate measurements from a variety of different locations. SERI has found them ideal for data-acquisition from multiple wind turbines and meteorological towers in wind parks. A major problem has been in providing the capability to quickly combine and examine incoming data from multiple PCM sources in the field. To solve this problem, SERI has developed a low-cost PC-based PCM Telemetry Data-Reduction System (PC-PCM System) to facilitate quick, in-the-field multiple-channel data analysis. The PC-PCM System consists of two basic components. First, PC-compatible hardware boards are used to decode and combine multiple PCM data streams. Up to four hardware boards can be installed in a single PC, which provides the capability to combine data from four PCM streams directly to PC disk or memory. Each stream can have up to 62 data channels. Second, a software package written for use under DOS was developed to simplify data-acquisition control and management. The software, called the Quick-Look Data Management Program, provides a quick, easy-to-use interface between the PC and multiple PCM data streams. The Quick-Look Data Management Program is a comprehensive menu-driven package used to organize, acquire, process, and display information from incoming PCM data streams. The paper describes both hardware and software aspects of the SERI PC-PCM system, concentrating on features that make it useful in an experiment test environment to quickly examine and verify incoming data from multiple PCM streams. Also discussed are problems and techniques associated with PC-based telemetry data-acquisition, processing, and real-time display.

  1. Reducing the cost of dietary assessment: self-completed recall and analysis of nutrition for use with children (SCRAN24).

    PubMed

    Foster, E; Hawkins, A; Delve, J; Adamson, A J

    2014-01-01

    Self-Completed Recall and Analysis of Nutrition (scran24) is a prototype computerised 24-h recall system for use with 11-16 year olds. It is based on the Multiple Pass 24-h Recall method and includes prompts and checks throughout the system for forgotten food items. The development of scran24 was informed by an extensive literature review, a series of focus groups and usability testing. The first stage of the recall is a quick list where the user is asked to input all the foods and drinks they remember consuming the previous day. The quick list is structured into meals and snacks. Once the quick list is complete, additional information is collected on each food to determine food type and to obtain an estimate of portion size using digital images of food. Foods are located within the system using a free text search, which is linked to the information entered into the quick list. A time is assigned to each eating occasion using drag and drop onto a timeline. The system prompts the user if no foods or drinks have been consumed within a 3-h time frame, or if fewer than three drinks have been consumed throughout the day. The food composition code and weight (g) of all items selected are automatically allocated and stored. Nutritional information can be generated automatically via the scran24 companion Access database. scran24 was very well received by young people and was relatively quick to complete. The accuracy and precision was close to that of similar computer-based systems currently used in dietary studies. © 2013 The Authors Journal of Human Nutrition and Dietetics © 2013 The British Dietetic Association Ltd.

  2. Wind turbine design codes: A comparison of the structural response

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Buhl, M.L. Jr.; Wright, A.D.; Pierce, K.G.

    2000-03-01

    The National Wind Technology Center (NWTC) of the National Renewable Energy Laboratory is continuing a comparison of several computer codes used in the design and analysis of wind turbines. The second part of this comparison determined how well the programs predict the structural response of wind turbines. In this paper, the authors compare the structural response for four programs: ADAMS, BLADED, FAST{_}AD, and YawDyn. ADAMS is a commercial, multibody-dynamics code from Mechanical Dynamics, Inc. BLADED is a commercial, performance and structural-response code from Garrad Hassan and Partners Limited. FAST{_}AD is a structural-response code developed by Oregon State University and themore » University of Utah for the NWTC. YawDyn is a structural-response code developed by the University of Utah for the NWTC. ADAMS, FAST{_}AD, and YawDyn use the University of Utah's AeroDyn subroutine package for calculating aerodynamic forces. Although errors were found in all the codes during this study, once they were fixed, the codes agreed surprisingly well for most of the cases and configurations that were evaluated. One unresolved discrepancy between BLADED and the AeroDyn-based codes was when there was blade and/or teeter motion in addition to a large yaw error.« less

  3. Real-time modeling of primitive environments through wavelet sensors and Hebbian learning

    NASA Astrophysics Data System (ADS)

    Vaccaro, James M.; Yaworsky, Paul S.

    1999-06-01

    Modeling the world through sensory input necessarily provides a unique perspective for the observer. Given a limited perspective, objects and events cannot always be encoded precisely but must involve crude, quick approximations to deal with sensory information in a real- time manner. As an example, when avoiding an oncoming car, a pedestrian needs to identify the fact that a car is approaching before ascertaining the model or color of the vehicle. In our methodology, we use wavelet-based sensors with self-organized learning to encode basic sensory information in real-time. The wavelet-based sensors provide necessary transformations while a rank-based Hebbian learning scheme encodes a self-organized environment through translation, scale and orientation invariant sensors. Such a self-organized environment is made possible by combining wavelet sets which are orthonormal, log-scale with linear orientation and have automatically generated membership functions. In earlier work we used Gabor wavelet filters, rank-based Hebbian learning and an exponential modulation function to encode textural information from images. Many different types of modulation are possible, but based on biological findings the exponential modulation function provided a good approximation of first spike coding of `integrate and fire' neurons. These types of Hebbian encoding schemes (e.g., exponential modulation, etc.) are useful for quick response and learning, provide several advantages over contemporary neural network learning approaches, and have been found to quantize data nonlinearly. By combining wavelets with Hebbian learning we can provide a real-time front-end for modeling an intelligent process, such as the autonomous control of agents in a simulated environment.

  4. Quick clay and landslides of clayey soils.

    PubMed

    Khaldoun, Asmae; Moller, Peder; Fall, Abdoulaye; Wegdam, Gerard; De Leeuw, Bert; Méheust, Yves; Otto Fossum, Jon; Bonn, Daniel

    2009-10-30

    We study the rheology of quick clay, an unstable soil responsible for many landslides. We show that above a critical stress the material starts flowing abruptly with a very large viscosity decrease caused by the flow. This leads to avalanche behavior that accounts for the instability of quick clay soils. Reproducing landslides on a small scale in the laboratory shows that an additional factor that determines the violence of the slides is the inhomogeneity of the flow. We propose a simple yield stress model capable of reproducing the laboratory landslide data, allowing us to relate landslides to the measured rheology.

  5. Quick Clay and Landslides of Clayey Soils

    NASA Astrophysics Data System (ADS)

    Khaldoun, Asmae; Moller, Peder; Fall, Abdoulaye; Wegdam, Gerard; de Leeuw, Bert; Méheust, Yves; Otto Fossum, Jon; Bonn, Daniel

    2009-10-01

    We study the rheology of quick clay, an unstable soil responsible for many landslides. We show that above a critical stress the material starts flowing abruptly with a very large viscosity decrease caused by the flow. This leads to avalanche behavior that accounts for the instability of quick clay soils. Reproducing landslides on a small scale in the laboratory shows that an additional factor that determines the violence of the slides is the inhomogeneity of the flow. We propose a simple yield stress model capable of reproducing the laboratory landslide data, allowing us to relate landslides to the measured rheology.

  6. Migration to Current Open Source Technologies by MagIC Enables a More Responsive Website, Quicker Development Times, and Increased Community Engagement

    NASA Astrophysics Data System (ADS)

    Jarboe, N.; Minnett, R.; Koppers, A.; Constable, C.; Tauxe, L.; Jonestrask, L.

    2017-12-01

    The Magnetics Information Consortium (MagIC) supports an online database for the paleo, geo, and rock magnetic communities ( https://earthref.org/MagIC ). Researchers can upload data into the archive and download data as selected with a sophisticated search system. MagIC has completed the transition from an Oracle backed, Perl based, server oriented website to an ElasticSearch backed, Meteor based thick client website technology stack. Using JavaScript on both the sever and the client enables increased code reuse and allows easy offloading many computational operations to the client for faster response. On-the-fly data validation, column header suggestion, and spreadsheet online editing are some new features available with the new system. The 3.0 data model, method codes, and vocabulary lists can be browsed via the MagIC website and more easily updated. Source code for MagIC is publicly available on GitHub ( https://github.com/earthref/MagIC ). The MagIC file format is natively compatible with the PmagPy ( https://github.com/PmagPy/PmagPy) paleomagnetic analysis software. MagIC files can now be downloaded from the database and viewed and interpreted in the PmagPy GUI based tool, pmag_gui. Changes or interpretations of the data can then be saved by pmag_gui in the MagIC 3.0 data format and easily uploaded to the MagIC database. The rate of new contributions to the database has been increasing with many labs contributing measurement level data for the first time in the last year. Over a dozen file format conversion scripts are available for translating non-MagIC measurement data files into the MagIC format for easy uploading. We will continue to work with more labs until the whole community has a manageable workflow for contributing their measurement level data. MagIC will continue to provide a global repository for archiving and retrieving paleomagnetic and rock magnetic data and, with the new system in place, be able to more quickly respond to the community's requests for changes and improvements.

  7. Development of 70 MW class superconducting generator with quick-response excitation

    NASA Astrophysics Data System (ADS)

    Miyaike, Kiyoshi; Kitajima, Toshio; Ito, Tetsuo

    2002-03-01

    The development of a superconducting generator had been carried out for 12 years under the first stage of a Super GM project. The 70 MW class model machine with quick response excitation was manufactured and evaluated in the project. This type of superconducting generator improves power system stability against rapid load fluctuations at the power system faults. This model machine achieved all development targets including high stability during rapid excitation control. It was also connected to the actual 77 kV electrical power grid as a synchronous condenser and proved advantages and high-operation reliability of the superconducting generator.

  8. Cracking the Code: Assessing Institutional Compliance with the Australian Code for the Responsible Conduct of Research

    ERIC Educational Resources Information Center

    Morris, Suzanne E.

    2010-01-01

    This paper provides a review of institutional authorship policies as required by the "Australian Code for the Responsible Conduct of Research" (the "Code") (National Health and Medical Research Council (NHMRC), the Australian Research Council (ARC) & Universities Australia (UA) 2007), and assesses them for Code compliance.…

  9. (Quickly) Testing the Tester via Path Coverage

    NASA Technical Reports Server (NTRS)

    Groce, Alex

    2009-01-01

    The configuration complexity and code size of an automated testing framework may grow to a point that the tester itself becomes a significant software artifact, prone to poor configuration and implementation errors. Unfortunately, testing the tester by using old versions of the software under test (SUT) may be impractical or impossible: test framework changes may have been motivated by interface changes in the tested system, or fault detection may become too expensive in terms of computing time to justify running until errors are detected on older versions of the software. We propose the use of path coverage measures as a "quick and dirty" method for detecting many faults in complex test frameworks. We also note the possibility of using techniques developed to diversify state-space searches in model checking to diversify test focus, and an associated classification of tester changes into focus-changing and non-focus-changing modifications.

  10. Development, Verification and Validation of Enclosure Radiation Capabilities in the CHarring Ablator Response (CHAR) Code

    NASA Technical Reports Server (NTRS)

    Salazar, Giovanni; Droba, Justin C.; Oliver, Brandon; Amar, Adam J.

    2016-01-01

    With the recent development of multi-dimensional thermal protection system (TPS) material response codes including the capabilities to account for radiative heating is a requirement. This paper presents the recent efforts to implement such capabilities in the CHarring Ablator Response (CHAR) code developed at NASA's Johnson Space Center. This work also describes the different numerical methods implemented in the code to compute view factors for radiation problems involving multiple surfaces. Furthermore, verification and validation of the code's radiation capabilities are demonstrated by comparing solutions to analytical results, to other codes, and to radiant test data.

  11. [The DRG responsible physician in trauma and orthopedic surgery. Surgeon, encoder, and link to medical controlling].

    PubMed

    Ruffing, T; Huchzermeier, P; Muhm, M; Winkler, H

    2014-05-01

    Precise coding is an essential requirement in order to generate a valid DRG. The aim of our study was to evaluate the quality of the initial coding of surgical procedures, as well as to introduce our "hybrid model" of a surgical specialist supervising medical coding and a nonphysician for case auditing. The department's DRG responsible physician as a surgical specialist has profound knowledge both in surgery and in DRG coding. At a Level 1 hospital, 1000 coded cases of surgical procedures were checked. In our department, the DRG responsible physician who is both a surgeon and encoder has proven itself for many years. The initial surgical DRG coding had to be corrected by the DRG responsible physician in 42.2% of cases. On average, one hour per working day was necessary. The implementation of a DRG responsible physician is a simple, effective way to connect medical and business expertise without interface problems. Permanent feedback promotes both medical and economic sensitivity for the improvement of coding quality.

  12. User's Manual for the ECLS-K Third Grade. Public-Use Data File and Electronic Code Book. Early Childhood Longitudinal Study, Kindergarten Class of 1998-99. NCES 2004-001

    ERIC Educational Resources Information Center

    Tourangeau, Karen; Brick, Mike; Le, Thanh; Wan, Siu; Weant, Margaret; Nord, Christine; Vaden-Kiernan, Nancy; Hagedorn, Mary; Bissett, Elizabeth; Dulaney, Richard; Fowler, Jean; Pollack, Judith; Rock, Donald; Weiss, Michael J.; Atkins-Burnett, Sally; Hausken, Elvira Germino; West, Jerry; Rathbun, Amy; Walston, Jill

    2004-01-01

    This document highlights key information needed to work with the Early Childhood Longitudinal Study, Kindergarten Class of 1998-99 (ECLS-K) data and points the reader to the appropriate sections of the User's Manual so that they can get started quickly. To read more about any particular topic, the reader should go to the indicated section of the…

  13. Thermal Protection System Imagery Inspection Management System -TIIMS

    NASA Technical Reports Server (NTRS)

    Goza, Sharon; Melendrez, David L.; Henningan, Marsha; LaBasse, Daniel; Smith, Daniel J.

    2011-01-01

    TIIMS is used during the inspection phases of every mission to provide quick visual feedback, detailed inspection data, and determination to the mission management team. This system consists of a visual Web page interface, an SQL database, and a graphical image generator. These combine to allow a user to ascertain quickly the status of the inspection process, and current determination of any problem zones. The TIIMS system allows inspection engineers to enter their determinations into a database and to link pertinent images and video to those database entries. The database then assigns criteria to each zone and tile, and via query, sends the information to a graphical image generation program. Using the official TIPS database tile positions and sizes, the graphical image generation program creates images of the current status of the orbiter, coloring zones, and tiles based on a predefined key code. These images are then displayed on a Web page using customized JAVA scripts to display the appropriate zone of the orbiter based on the location of the user's cursor. The close-up graphic and database entry for that particular zone can then be seen by selecting the zone. This page contains links into the database to access the images used by the inspection engineer when they make the determination entered into the database. Status for the inspection zones changes as determinations are refined and shown by the appropriate color code.

  14. Measurement properties of the QuickDASH (disabilities of the arm, shoulder and hand) outcome measure and cross-cultural adaptations of the QuickDASH: a systematic review.

    PubMed

    Kennedy, Carol A; Beaton, Dorcas E; Smith, Peter; Van Eerd, Dwayne; Tang, Kenneth; Inrig, Taucha; Hogg-Johnson, Sheilah; Linton, Denise; Couban, Rachel

    2013-11-01

    To identify and synthesize evidence for the measurement properties of the QuickDASH, a shortened version of the 30-item DASH (Disabilities of the Arm, Shoulder and Hand) instrument. This systematic review used a best evidence synthesis approach to critically appraise the measurement properties [using COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN)] of the QuickDASH and cross-cultural adaptations. A standard search strategy was conducted between 2005 (year of first publication of QuickDASH) and March 2011 in MEDLINE, EMBASE and CINAHL. The search identified 14 studies to include in the best evidence synthesis of the QuickDASH. A further 11 studies were identified on eight cross-cultural adaptation versions. Many measurement properties of the QuickDASH have been evaluated in multiple studies and across most of the measurement properties. The best evidence synthesis of the QuickDASH English version suggests that this tool is performing well with strong positive evidence for reliability and validity (hypothesis testing), and moderate positive evidence for structural validity testing. Strong negative evidence was found for responsiveness due to lower correlations with global estimates of change. Information about the measurement properties of the cross-cultural adaptation versions is still lacking, or the available information is of poor overall methodological quality.

  15. Quick returns and night work as predictors of sleep quality, fatigue, work-family balance and satisfaction with work hours.

    PubMed

    Dahlgren, Anna; Tucker, Philip; Gustavsson, Petter; Rudman, Ann

    2016-01-01

    Quick returns (intervals of <11 h between the end of one shift and the start of the next) are associated with short sleeps and fatigue on the subsequent shift. Recent evidence suggests that shift workers regard quick returns as being more problematic than night work. The current study explored quick returns and night work in terms of their impact on sleep, unwinding, recovery, exhaustion, satisfaction with work hours and work-family interference. Data from the 2006 cohort of Swedish nursing students within the national Longitudinal Analysis of Nursing Education (LANE) study were analysed (N = 1459). Respondents completed a questionnaire prior to graduation (response rate 69.2%) and 3 years after graduation (65.9%). The analyses examined associations between frequency of quick returns and night work and measures taken in year three, while adjusting for confounding factors (in year three and prior graduation). Frequency of quick returns was a significant predictor of poor sleep quality, short sleeps, unwinding, exhaustion, satisfaction with work hours and work-to-family interference, with higher frequency predicting more negative outcomes. Quick returns did not predict recovery after rest days. Frequency of night work did not predict any of the outcomes. In conclusion, quick returns were an important determinant of sleep, recovery and wellbeing, whereas night work did not show such an association.

  16. A low-cost PC-based telemetry data-reduction system

    NASA Astrophysics Data System (ADS)

    Simms, D. A.; Butterfield, C. P.

    1990-04-01

    The Solar Energy Research Institute's (SERI) Wind Research Branch is using Pulse Code Modulation (PCM) telemetry data-acquisition systems to study horizontal-axis wind turbines. PCM telemetry systems are used in test installations that require accurate multiple-channel measurements taken from a variety of different locations. SERI has found them ideal for use in tests requiring concurrent acquisition of data-reduction system to facilitate quick, in-the-field multiple-channel data analysis. Called the PC-PCM System, it consists of two basic components. First, AT-compatible hardware boards are used for decoding and combining PCM data streams. Up to four hardware boards can be installed in a single PC, which provides the capability to combine data from four PCM streams directly to PC disk or memory. Each stream can have up to 62 data channels. Second, a software package written for the DOS operating system was developed to simplify data-acquisition control and management. The software provides a quick, easy-to-use interface between the PC and PCM data streams. Called the Quick-Look Data Management Program, it is a comprehensive menu-driven package used to organize, acquire, process, and display information from incoming PCM data streams. This paper describes both hardware and software aspects of the SERI PC-PCM system, concentrating on features that make it useful in an experiment test environment to quickly examine and verify incoming data. Also discussed are problems and techniques associated with PC-based telemetry data acquisition, processing, and real-time display.

  17. Nanotechnology Infrared Optics for Astronomy Missions

    NASA Technical Reports Server (NTRS)

    Frogel, Jay (Technical Monitor); Smith, Howard A.

    2004-01-01

    We have used the "MicroStripes" code (Flomerics, Inc.) to perform full-, near- and far-field diffraction modeling of metal mesh performance on substrates. Our Miles Code software, which approximates the full calculation in a quick, gui-based window, is useful as an iterative device by adjusting the input parameters (index of refraction, thickness, etc.) to provide agreement with the full calculation. However, despite the somewhat extravagant claims by the MicroStripes manufacturer, this code is also not perfect because numerous free parameters must be set. Key among these, as identified in our earlier papers and proposal documents, is the high frequency (i.e., far IR) character of the real and imaginary parts of the index of refraction of the metal mesh, the high frequency character of the real and imaginary parts of the index of refraction of the substrate, and the character of the interface between the mesh and the substrate material, and in particular the suppression (or possible enhancement) of surface effects at the interface.

  18. Design and implementation in VHDL code of the two-dimensional fast Fourier transform for frequency filtering, convolution and correlation operations

    NASA Astrophysics Data System (ADS)

    Vilardy, Juan M.; Giacometto, F.; Torres, C. O.; Mattos, L.

    2011-01-01

    The two-dimensional Fast Fourier Transform (FFT 2D) is an essential tool in the two-dimensional discrete signals analysis and processing, which allows developing a large number of applications. This article shows the description and synthesis in VHDL code of the FFT 2D with fixed point binary representation using the programming tool Simulink HDL Coder of Matlab; showing a quick and easy way to handle overflow, underflow and the creation registers, adders and multipliers of complex data in VHDL and as well as the generation of test bench for verification of the codes generated in the ModelSim tool. The main objective of development of the hardware architecture of the FFT 2D focuses on the subsequent completion of the following operations applied to images: frequency filtering, convolution and correlation. The description and synthesis of the hardware architecture uses the XC3S1200E family Spartan 3E FPGA from Xilinx Manufacturer.

  19. Reliability and Validity of the Dyadic Observed Communication Scale (DOCS).

    PubMed

    Hadley, Wendy; Stewart, Angela; Hunter, Heather L; Affleck, Katelyn; Donenberg, Geri; Diclemente, Ralph; Brown, Larry K

    2013-02-01

    We evaluated the reliability and validity of the Dyadic Observed Communication Scale (DOCS) coding scheme, which was developed to capture a range of communication components between parents and adolescents. Adolescents and their caregivers were recruited from mental health facilities for participation in a large, multi-site family-based HIV prevention intervention study. Seventy-one dyads were randomly selected from the larger study sample and coded using the DOCS at baseline. Preliminary validity and reliability of the DOCS was examined using various methods, such as comparing results to self-report measures and examining interrater reliability. Results suggest that the DOCS is a reliable and valid measure of observed communication among parent-adolescent dyads that captures both verbal and nonverbal communication behaviors that are typical intervention targets. The DOCS is a viable coding scheme for use by researchers and clinicians examining parent-adolescent communication. Coders can be trained to reliably capture individual and dyadic components of communication for parents and adolescents and this complex information can be obtained relatively quickly.

  20. A Software Development Platform for Wearable Medical Applications.

    PubMed

    Zhang, Ruikai; Lin, Wei

    2015-10-01

    Wearable medical devices have become a leading trend in healthcare industry. Microcontrollers are computers on a chip with sufficient processing power and preferred embedded computing units in those devices. We have developed a software platform specifically for the design of the wearable medical applications with a small code footprint on the microcontrollers. It is supported by the open source real time operating system FreeRTOS and supplemented with a set of standard APIs for the architectural specific hardware interfaces on the microcontrollers for data acquisition and wireless communication. We modified the tick counter routine in FreeRTOS to include a real time soft clock. When combined with the multitasking features in the FreeRTOS, the platform offers the quick development of wearable applications and easy porting of the application code to different microprocessors. Test results have demonstrated that the application software developed using this platform are highly efficient in CPU usage while maintaining a small code foot print to accommodate the limited memory space in microcontrollers.

  1. Development and Verification of Enclosure Radiation Capabilities in the CHarring Ablator Response (CHAR) Code

    NASA Technical Reports Server (NTRS)

    Salazar, Giovanni; Droba, Justin C.; Oliver, Brandon; Amar, Adam J.

    2016-01-01

    With the recent development of multi-dimensional thermal protection system (TPS) material response codes, the capability to account for surface-to-surface radiation exchange in complex geometries is critical. This paper presents recent efforts to implement such capabilities in the CHarring Ablator Response (CHAR) code developed at NASA's Johnson Space Center. This work also describes the different numerical methods implemented in the code to compute geometric view factors for radiation problems involving multiple surfaces. Verification of the code's radiation capabilities and results of a code-to-code comparison are presented. Finally, a demonstration case of a two-dimensional ablating cavity with enclosure radiation accounting for a changing geometry is shown.

  2. Code-to-Code Comparison, and Material Response Modeling of Stardust and MSL using PATO and FIAT

    NASA Technical Reports Server (NTRS)

    Omidy, Ali D.; Panerai, Francesco; Martin, Alexandre; Lachaud, Jean R.; Cozmuta, Ioana; Mansour, Nagi N.

    2015-01-01

    This report provides a code-to-code comparison between PATO, a recently developed high fidelity material response code, and FIAT, NASA's legacy code for ablation response modeling. The goal is to demonstrates that FIAT and PATO generate the same results when using the same models. Test cases of increasing complexity are used, from both arc-jet testing and flight experiment. When using the exact same physical models, material properties and boundary conditions, the two codes give results that are within 2% of errors. The minor discrepancy is attributed to the inclusion of the gas phase heat capacity (cp) in the energy equation in PATO, and not in FIAT.

  3. Self-Scheduling Parallel Methods for Multiple Serial Codes with Application to WOPWOP

    NASA Technical Reports Server (NTRS)

    Long, Lyle N.; Brentner, Kenneth S.

    2000-01-01

    This paper presents a scheme for efficiently running a large number of serial jobs on parallel computers. Two examples are given of computer programs that run relatively quickly, but often they must be run numerous times to obtain all the results needed. It is very common in science and engineering to have codes that are not massive computing challenges in themselves, but due to the number of instances that must be run, they do become large-scale computing problems. The two examples given here represent common problems in aerospace engineering: aerodynamic panel methods and aeroacoustic integral methods. The first example simply solves many systems of linear equations. This is representative of an aerodynamic panel code where someone would like to solve for numerous angles of attack. The complete code for this first example is included in the appendix so that it can be readily used by others as a template. The second example is an aeroacoustics code (WOPWOP) that solves the Ffowcs Williams Hawkings equation to predict the far-field sound due to rotating blades. In this example, one quite often needs to compute the sound at numerous observer locations, hence parallelization is utilized to automate the noise computation for a large number of observers.

  4. Response surface method in geotechnical/structural analysis, phase 1

    NASA Astrophysics Data System (ADS)

    Wong, F. S.

    1981-02-01

    In the response surface approach, an approximating function is fit to a long running computer code based on a limited number of code calculations. The approximating function, called the response surface, is then used to replace the code in subsequent repetitive computations required in a statistical analysis. The procedure of the response surface development and feasibility of the method are shown using a sample problem in slop stability which is based on data from centrifuge experiments of model soil slopes and involves five random soil parameters. It is shown that a response surface can be constructed based on as few as four code calculations and that the response surface is computationally extremely efficient compared to the code calculation. Potential applications of this research include probabilistic analysis of dynamic, complex, nonlinear soil/structure systems such as slope stability, liquefaction, and nuclear reactor safety.

  5. The pros and cons of code validation

    NASA Technical Reports Server (NTRS)

    Bobbitt, Percy J.

    1988-01-01

    Computational and wind tunnel error sources are examined and quantified using specific calculations of experimental data, and a substantial comparison of theoretical and experimental results, or a code validation, is discussed. Wind tunnel error sources considered include wall interference, sting effects, Reynolds number effects, flow quality and transition, and instrumentation such as strain gage balances, electronically scanned pressure systems, hot film gages, hot wire anemometers, and laser velocimeters. Computational error sources include math model equation sets, the solution algorithm, artificial viscosity/dissipation, boundary conditions, the uniqueness of solutions, grid resolution, turbulence modeling, and Reynolds number effects. It is concluded that, although improvements in theory are being made more quickly than in experiments, wind tunnel research has the advantage of the more realistic transition process of a right turbulence model in a free-transition test.

  6. Tool for Rapid Analysis of Monte Carlo Simulations

    NASA Technical Reports Server (NTRS)

    Restrepo, Carolina; McCall, Kurt E.; Hurtado, John E.

    2013-01-01

    Designing a spacecraft, or any other complex engineering system, requires extensive simulation and analysis work. Oftentimes, the large amounts of simulation data generated are very difficult and time consuming to analyze, with the added risk of overlooking potentially critical problems in the design. The authors have developed a generic data analysis tool that can quickly sort through large data sets and point an analyst to the areas in the data set that cause specific types of failures. The first version of this tool was a serial code and the current version is a parallel code, which has greatly increased the analysis capabilities. This paper describes the new implementation of this analysis tool on a graphical processing unit, and presents analysis results for NASA's Orion Monte Carlo data to demonstrate its capabilities.

  7. 1997 Report to the Congress on Ballistic Missile Defense.

    DTIC Science & Technology

    1997-10-01

    Infrared Arrays • Quantum Well Infrared Photodector (QWIP) Focal Plane Array (FPA) • Staring Si Impurity Band Conduction Extremely Sensitive Focal...to be flown on STRV lc/d include a Quantum Well Infrared Photometer (QWIP) sensor and a multifunctional compos- ite structure. The Space Technology...Peoples Republic of China Platinum Silicide Quick Reaction Program Quick Response Program Quantum Well Infrared Photometer Research and

  8. Evaluation of NeQuick as a model to characterize the Equatorial Ionization Anomaly over Africa using data ingestion

    NASA Astrophysics Data System (ADS)

    Migoya-Orué, Y.; Folarin-Olufunmilayo, O.; Radicella, S.; Alazo-Cuartas, K.; Rabiu, A. B.

    2017-10-01

    Global Ionospheric Maps (GIM) of vertical Total Electron Content (TEC) are utilized in an ingestion approach to generate a 3D specification of the ionosphere over the African Equatorial Ionospheric Anomaly (EIA) by using NeQuick model. The effectiveness of the GIM to specify the ionosphere over the African region has been assessed during the IONAF, a project under the ESA's Alcantara Initiative. A series of analysis that takes into account the day-to-day variability seen by the GIM and by specific receivers' ground stations have shown that the vertical TEC derived from the GIMs (CODE) presents a systematic but not necessarily constant positive offset with respect to the corresponding data obtained from individual stations. These offsets have been taken into account in the ingestion process. Therefore, as option, an 'adjustment' to the vertical TEC from CODE has been introduced, to see if it has any effect in modeling the ionosphere in the region of interest. One of the outputs of the ingestion process is a series of maps of foF2 over the African EIA. A validation with foF2 values from the only ionosonde station available in that period, Ilorin, for some months of the year 2010 has been performed. Another comparison with the slant TEC obtained in the 3D specification using GNSS data from the station bjco, Benin, in a given day has been done. Results show that the mismodelings are reduced when the positive offset is taken out from the maps. The paper concludes with an investigation of the effects of the NeQuick bottomside thickness parameter (B2bot) mismodeling on the electron density retrieval. A parameterization of experimental B2bot as a function of time is used to explore the possibility of reducing the mismodeling when foF2 is retrieved from the 3D specification of the ionosphere obtained through the data ingestion process.

  9. Manual versus automated coding of free-text self-reported medication data in the 45 and Up Study: a validation study.

    PubMed

    Gnjidic, Danijela; Pearson, Sallie-Anne; Hilmer, Sarah N; Basilakis, Jim; Schaffer, Andrea L; Blyth, Fiona M; Banks, Emily

    2015-03-30

    Increasingly, automated methods are being used to code free-text medication data, but evidence on the validity of these methods is limited. To examine the accuracy of automated coding of previously keyed in free-text medication data compared with manual coding of original handwritten free-text responses (the 'gold standard'). A random sample of 500 participants (475 with and 25 without medication data in the free-text box) enrolled in the 45 and Up Study was selected. Manual coding involved medication experts keying in free-text responses and coding using Anatomical Therapeutic Chemical (ATC) codes (i.e. chemical substance 7-digit level; chemical subgroup 5-digit; pharmacological subgroup 4-digit; therapeutic subgroup 3-digit). Using keyed-in free-text responses entered by non-experts, the automated approach coded entries using the Australian Medicines Terminology database and assigned corresponding ATC codes. Based on manual coding, 1377 free-text entries were recorded and, of these, 1282 medications were coded to ATCs manually. The sensitivity of automated coding compared with manual coding was 79% (n = 1014) for entries coded at the exact ATC level, and 81.6% (n = 1046), 83.0% (n = 1064) and 83.8% (n = 1074) at the 5, 4 and 3-digit ATC levels, respectively. The sensitivity of automated coding for blank responses was 100% compared with manual coding. Sensitivity of automated coding was highest for prescription medications and lowest for vitamins and supplements, compared with the manual approach. Positive predictive values for automated coding were above 95% for 34 of the 38 individual prescription medications examined. Automated coding for free-text prescription medication data shows very high to excellent sensitivity and positive predictive values, indicating that automated methods can potentially be useful for large-scale, medication-related research.

  10. The BSM-AI project: SUSY-AI-generalizing LHC limits on supersymmetry with machine learning

    NASA Astrophysics Data System (ADS)

    Caron, Sascha; Kim, Jong Soo; Rolbiecki, Krzysztof; de Austri, Roberto Ruiz; Stienen, Bob

    2017-04-01

    A key research question at the Large Hadron Collider is the test of models of new physics. Testing if a particular parameter set of such a model is excluded by LHC data is a challenge: it requires time consuming generation of scattering events, simulation of the detector response, event reconstruction, cross section calculations and analysis code to test against several hundred signal regions defined by the ATLAS and CMS experiments. In the BSM-AI project we approach this challenge with a new idea. A machine learning tool is devised to predict within a fraction of a millisecond if a model is excluded or not directly from the model parameters. A first example is SUSY-AI, trained on the phenomenological supersymmetric standard model (pMSSM). About 300, 000 pMSSM model sets - each tested against 200 signal regions by ATLAS - have been used to train and validate SUSY-AI. The code is currently able to reproduce the ATLAS exclusion regions in 19 dimensions with an accuracy of at least 93%. It has been validated further within the constrained MSSM and the minimal natural supersymmetric model, again showing high accuracy. SUSY-AI and its future BSM derivatives will help to solve the problem of recasting LHC results for any model of new physics. SUSY-AI can be downloaded from http://susyai.hepforge.org/. An on-line interface to the program for quick testing purposes can be found at http://www.susy-ai.org/.

  11. Expression of Multiple Stress Response Genes by Escherichia Coli Under Modeled Reduced Gravity

    NASA Astrophysics Data System (ADS)

    Vukanti, Raja; Leff, Laura G.

    2012-09-01

    Bacteria, in response to changes in their environment, quickly regulate gene expression; hence, transcriptional profiling has been widely used to characterize bacterial responses to various environmental conditions. In this study, we used clinorotation to grow bacteria under low-sedimentation, -shear, and -turbulence conditions (referred to as modeled reduced gravity, MRG, below) which profoundly impacts bacteria including causing elevated resistance to multiple environmental stresses. To explore potential mechanisms behind the multiple stress resistance response to MRG, we assessed expression levels of E. coli genes, using reverse transcription followed by real-time-PCR, involved in specific stress and general stress responses under MRG and normal gravity (NG) in nutritionally rich and minimal media, and during exponential and stationary phases of growth. In addition, growth rates as well as physico-chemical parameters of culture media were examined. Over-expression of stress response genes (csiD, cstA, katE, otsA, treA) occurred under MRG compared to NG controls, but only during the later stages of growth in rich medium demonstrating that bacterial response to MRG varies with growth-medium and -phase. At stationary phase in rich medium under MRG and NG, E. coli had similar growth rates (based on rRNA-leader abundance) and yields (cell mass and numbers); this coupled, with observations of simultaneous induction of starvation response genes (csiD and cstA) suggests the multiple stress resistance phenotype under MRG could be attributable to microzones of nutrient unavailability around cells. Overall, in rich medium, the response resembled the general stress response (GSR) that E. coli develops during stationary phase of growth. Along these same lines, induction of genes coding for GSR was reversed by improving nutritional conditions under MRG. The reversal of GSR under MRG suggests that the multiple stress response exhibited is not specific to MRG but may result from nutrient limitation experienced by bacteria after incubation in nutrient-rich media under these conditions.

  12. Response Rates for Patient-Reported Outcomes Using Web-Based Versus Paper Questionnaires: Comparison of Two Invitational Methods in Older Colorectal Cancer Patients

    PubMed Central

    Vissers, Pauline AJ; Mols, Floortje; Thong, Melissa SY; van de Poll-Franse, Lonneke V

    2015-01-01

    Background Improving questionnaire response rates is an everlasting issue for research. Today, the Internet can easily be used to collect data quickly. However, collecting data on the Internet can lead to biased samples because not everyone is able to access or use the Internet. The older population, for example, is much less likely to use the Internet. The Patient-Reported Outcomes Following Initial Treatment and Long-Term Evaluation of Survivorship (PROFILES) registry offers a platform to collect Web-based and paper questionnaires and to try different measures to improve response rates. Objective In this study, our aim was to study the influence of two methods of invitation on the response rate. Our second aim was to examine the preference of questionnaire mode of administration (paper or Web-based) for the older patient in particular. Methods To test these two invitational methods, 3406 colorectal cancer patients between ages 18 and 85 years received an invitation containing an access code for the Web-based questionnaire. They could also request a paper questionnaire with an included reply card (paper-optional group). In contrast, 179 randomly selected colorectal cancer patients received a paper questionnaire with the invitation (paper-included group). They could also choose to fill out the Web-based questionnaire with the included access code. Results Response rates did not differ between the paper-optional and the paper-included groups (73.14%, 2491/3406 and 74.9%, 134/179, P=.57). In the paper-optional group, online response was significantly higher when compared to the paper-included group (41.23%, 1027/2491 vs 12.7%, 17/134, P<.001). The majority of online respondents responded after the first invitation (95.33%, 979/1027), which was significantly higher than the paper respondents (52.19%, 764/1464, P<.001). Respondents aged 70 years and older chose to fill out a paper questionnaire more often (71.0%, 677/954). In the oldest age group (≥80 years), 18.2% (61/336) of the respondents filled out a Web-based questionnaire. Conclusions The lack of difference in response rates between invitation modes implies that researchers can leave out a paper questionnaire at invitation without lowering response rates. It may be preferable not to include a paper questionnaire because more respondents then will fill out a Web-based questionnaire, which will lead to faster available data. However, due to respondent preference, it is not likely that paper questionnaires can be left out completely in the near future. PMID:25953059

  13. The StarView intelligent query mechanism

    NASA Technical Reports Server (NTRS)

    Semmel, R. D.; Silberberg, D. P.

    1993-01-01

    The StarView interface is being developed to facilitate the retrieval of scientific and engineering data produced by the Hubble Space Telescope. While predefined screens in the interface can be used to specify many common requests, ad hoc requests require a dynamic query formulation capability. Unfortunately, logical level knowledge is too sparse to support this capability. In particular, essential formulation knowledge is lost when the domain of interest is mapped to a set of database relation schemas. Thus, a system known as QUICK has been developed that uses conceptual design knowledge to facilitate query formulation. By heuristically determining strongly associated objects at the conceptual level, QUICK is able to formulate semantically reasonable queries in response to high-level requests that specify only attributes of interest. Moreover, by exploiting constraint knowledge in the conceptual design, QUICK assures that queries are formulated quickly and will execute efficiently.

  14. 7 CFR 1486.206 - What is the Quick Response Marketing Fund?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Marketing Fund must identify specific market access issues that also face time constraints. Application... responsiveness to time-sensitive marketing problems or opportunities, such as a change in an import regime or the...

  15. Robust hashing with local models for approximate similarity search.

    PubMed

    Song, Jingkuan; Yang, Yi; Li, Xuelong; Huang, Zi; Yang, Yang

    2014-07-01

    Similarity search plays an important role in many applications involving high-dimensional data. Due to the known dimensionality curse, the performance of most existing indexing structures degrades quickly as the feature dimensionality increases. Hashing methods, such as locality sensitive hashing (LSH) and its variants, have been widely used to achieve fast approximate similarity search by trading search quality for efficiency. However, most existing hashing methods make use of randomized algorithms to generate hash codes without considering the specific structural information in the data. In this paper, we propose a novel hashing method, namely, robust hashing with local models (RHLM), which learns a set of robust hash functions to map the high-dimensional data points into binary hash codes by effectively utilizing local structural information. In RHLM, for each individual data point in the training dataset, a local hashing model is learned and used to predict the hash codes of its neighboring data points. The local models from all the data points are globally aligned so that an optimal hash code can be assigned to each data point. After obtaining the hash codes of all the training data points, we design a robust method by employing l2,1 -norm minimization on the loss function to learn effective hash functions, which are then used to map each database point into its hash code. Given a query data point, the search process first maps it into the query hash code by the hash functions and then explores the buckets, which have similar hash codes to the query hash code. Extensive experimental results conducted on real-life datasets show that the proposed RHLM outperforms the state-of-the-art methods in terms of search quality and efficiency.

  16. The fourfold way of the genetic code.

    PubMed

    Jiménez-Montaño, Miguel Angel

    2009-11-01

    We describe a compact representation of the genetic code that factorizes the table in quartets. It represents a "least grammar" for the genetic language. It is justified by the Klein-4 group structure of RNA bases and codon doublets. The matrix of the outer product between the column-vector of bases and the corresponding row-vector V(T)=(C G U A), considered as signal vectors, has a block structure consisting of the four cosets of the KxK group of base transformations acting on doublet AA. This matrix, translated into weak/strong (W/S) and purine/pyrimidine (R/Y) nucleotide classes, leads to a code table with mixed and unmixed families in separate regions. A basic difference between them is the non-commuting (R/Y) doublets: AC/CA, GU/UG. We describe the degeneracy in the canonical code and the systematic changes in deviant codes in terms of the divisors of 24, employing modulo multiplication groups. We illustrate binary sub-codes characterizing mutations in the quartets. We introduce a decision-tree to predict the mode of tRNA recognition corresponding to each codon, and compare our result with related findings by Jestin and Soulé [Jestin, J.-L., Soulé, C., 2007. Symmetries by base substitutions in the genetic code predict 2' or 3' aminoacylation of tRNAs. J. Theor. Biol. 247, 391-394], and the rearrangements of the table by Delarue [Delarue, M., 2007. An asymmetric underlying rule in the assignment of codons: possible clue to a quick early evolution of the genetic code via successive binary choices. RNA 13, 161-169] and Rodin and Rodin [Rodin, S.N., Rodin, A.S., 2008. On the origin of the genetic code: signatures of its primordial complementarity in tRNAs and aminoacyl-tRNA synthetases. Heredity 100, 341-355], respectively.

  17. Purple L1 Milestone Review Panel TotalView Debugger Functionality and Performance for ASC Purple

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wolfe, M

    2006-12-12

    ASC code teams require a robust software debugging tool to help developers quickly find bugs in their codes and get their codes running. Development debugging commonly runs up to 512 processes. Production jobs run up to full ASC Purple scale, and at times require introspection while running. Developers want a debugger that runs on all their development and production platforms and that works with all compilers and runtimes used with ASC codes. The TotalView Multiprocess Debugger made by Etnus was specified for ASC Purple to address this needed capability. The ASC Purple environment builds on the environment seen by TotalViewmore » on ASCI White. The debugger must now operate with the Power5 CPU, Federation switch, AIX 5.3 operating system including large pages, IBM compilers 7 and 9, POE 4.2 parallel environment, and rs6000 SLURM resource manager. Users require robust, basic debugger functionality with acceptable performance at development debugging scale. A TotalView installation must be provided at the beginning of the early user access period that meets these requirements. A functional enhancement, fast conditional data watchpoints, and a scalability enhancement, capability up to 8192 processes, are to be demonstrated.« less

  18. Simulated Raman Spectral Analysis of Organic Molecules

    NASA Astrophysics Data System (ADS)

    Lu, Lu

    The advent of the laser technology in the 1960s solved the main difficulty of Raman spectroscopy, resulted in simplified Raman spectroscopy instruments and also boosted the sensitivity of the technique. Up till now, Raman spectroscopy is commonly used in chemistry and biology. As vibrational information is specific to the chemical bonds, Raman spectroscopy provides fingerprints to identify the type of molecules in the sample. In this thesis, we simulate the Raman Spectrum of organic and inorganic materials by General Atomic and Molecular Electronic Structure System (GAMESS) and Gaussian, two computational codes that perform several general chemistry calculations. We run these codes on our CPU-based high-performance cluster (HPC). Through the message passing interface (MPI), a standardized and portable message-passing system which can make the codes run in parallel, we are able to decrease the amount of time for computation and increase the sizes and capacities of systems simulated by the codes. From our simulations, we will set up a database that allows search algorithm to quickly identify N-H and O-H bonds in different materials. Our ultimate goal is to analyze and identify the spectra of organic matter compositions from meteorites and compared these spectra with terrestrial biologically-produced amino acids and residues.

  19. Modeling coherent errors in quantum error correction

    NASA Astrophysics Data System (ADS)

    Greenbaum, Daniel; Dutton, Zachary

    2018-01-01

    Analysis of quantum error correcting codes is typically done using a stochastic, Pauli channel error model for describing the noise on physical qubits. However, it was recently found that coherent errors (systematic rotations) on physical data qubits result in both physical and logical error rates that differ significantly from those predicted by a Pauli model. Here we examine the accuracy of the Pauli approximation for noise containing coherent errors (characterized by a rotation angle ɛ) under the repetition code. We derive an analytic expression for the logical error channel as a function of arbitrary code distance d and concatenation level n, in the small error limit. We find that coherent physical errors result in logical errors that are partially coherent and therefore non-Pauli. However, the coherent part of the logical error is negligible at fewer than {ε }-({dn-1)} error correction cycles when the decoder is optimized for independent Pauli errors, thus providing a regime of validity for the Pauli approximation. Above this number of correction cycles, the persistent coherent logical error will cause logical failure more quickly than the Pauli model would predict, and this may need to be combated with coherent suppression methods at the physical level or larger codes.

  20. System Characterization Results for the QuickBird Sensor

    NASA Technical Reports Server (NTRS)

    Holekamp, Kara; Ross, Kenton; Blonski, Slawomir

    2007-01-01

    An overall system characterization was performed on several DigitalGlobe' QuickBird image products by the NASA Applied Research & Technology Project Office (formerly the Applied Sciences Directorate) at the John C. Stennis Space Center. This system characterization incorporated geopositional accuracy assessments, a spatial resolution assessment, and a radiometric calibration assessment. Geopositional assessments of standard georeferenced multispectral products were obtained using an array of accurately surveyed geodetic targets evenly spaced throughout a scene. Geopositional accuracy was calculated in terms of circular error. Spatial resolution of QuickBird panchromatic imagery was characterized based on edge response measurements using edge targets and the tilted-edge technique. Relative edge response was estimated as a geometric mean of normalized edge response differences measured in two directions of image pixels at points distanced from the edge by -0.5 and 0.5 of ground sample distance. A reflectance-based vicarious calibration approach, based on ground-based measurements and radiative transfer calculations, was used to estimate at-sensor radiance. These values were compared to those measured by the sensor to determine the sensor's radiometric accuracy. All imagery analyzed was acquired between fall 2005 and spring 2006. These characterization results were compared to previous years' results to identify any temporal drifts or trends.

  1. A Tutorial on RxODE: Simulating Differential Equation Pharmacometric Models in R.

    PubMed

    Wang, W; Hallow, K M; James, D A

    2016-01-01

    This tutorial presents the application of an R package, RxODE, that facilitates quick, efficient simulations of ordinary differential equation models completely within R. Its application is illustrated through simulation of design decision effects on an adaptive dosing regimen. The package provides an efficient, versatile way to specify dosing scenarios and to perform simulation with variability with minimal custom coding. Models can be directly translated to Rshiny applications to facilitate interactive, real-time evaluation/iteration on simulation scenarios.

  2. Technical Solution for Mitigating Radio-Frequency (RF) Interference to Air Traffic Control Communications

    DTIC Science & Technology

    2013-09-01

    the fiber-optic receiver. When electrical power was restored by reinserting the plug, there could be no guarantee that all of the relays within the...useable set of coded instructions was expected to take approximately 3 man-months to develop and would incur costs, in labor , much greater than the...man-hour labor load was expected to be only about a month, the inability to quickly verify a “final” circuit design represented the highest risk

  3. Quick-Turn Finite Element Analysis for Plug-and-Play Satellite Structures

    DTIC Science & Technology

    2007-03-01

    produced from 0.375 inch round stock and turned on a machine lathe to achieve the shoulder feature and drilled to make it hollow. Figure 3.1...component, a linear taper was machined from the connection shoulder to the solar panel connecting fork. The part was then turned using the machine lathe ...utilizing a modern five-axis Computer Numerical Code ( CNC ) machine mill, the process time could be reduced by as much as seventy-five percent and the

  4. Pediatric office emergencies.

    PubMed

    Fuchs, Susan

    2013-10-01

    Pediatricians regularly see emergencies in the office, or children that require transfer to an emergency department, or hospitalization. An office self-assessment is the first step in determining how to prepare for an emergency. The use of mock codes and skill drills make office personnel feel less anxious about medical emergencies. Emergency information forms provide valuable, quick information about complex patients for emergency medical services and other physicians caring for patients. Furthermore, disaster planning should be part of an office preparedness plan. Copyright © 2013 Elsevier Inc. All rights reserved.

  5. Air breathing engine/rocket trajectory optimization

    NASA Technical Reports Server (NTRS)

    Smith, V. K., III

    1979-01-01

    This research has focused on improving the mathematical models of the air-breathing propulsion systems, which can be mated with the rocket engine model and incorporated in trajectory optimization codes. Improved engine simulations provided accurate representation of the complex cycles proposed for advanced launch vehicles, thereby increasing the confidence in propellant use and payload calculations. The versatile QNEP (Quick Navy Engine Program) was modified to allow treatment of advanced turboaccelerator cycles using hydrogen or hydrocarbon fuels and operating in the vehicle flow field.

  6. CELFE/NASTRAN Code for the Analysis of Structures Subjected to High Velocity Impact

    NASA Technical Reports Server (NTRS)

    Chamis, C. C.

    1978-01-01

    CELFE (Coupled Eulerian Lagrangian Finite Element)/NASTRAN Code three-dimensional finite element code has the capability for analyzing of structures subjected to high velocity impact. The local response is predicted by CELFE and, for large problems, the far-field impact response is predicted by NASTRAN. The coupling of the CELFE code with NASTRAN (CELFE/NASTRAN code) and the application of the code to selected three-dimensional high velocity impact problems are described.

  7. Applications of Phase-Based Motion Processing

    NASA Technical Reports Server (NTRS)

    Branch, Nicholas A.; Stewart, Eric C.

    2018-01-01

    Image pyramids provide useful information in determining structural response at low cost using commercially available cameras. The current effort applies previous work on the complex steerable pyramid to analyze and identify imperceptible linear motions in video. Instead of implicitly computing motion spectra through phase analysis of the complex steerable pyramid and magnifying the associated motions, instead present a visual technique and the necessary software to display the phase changes of high frequency signals within video. The present technique quickly identifies regions of largest motion within a video with a single phase visualization and without the artifacts of motion magnification, but requires use of the computationally intensive Fourier transform. While Riesz pyramids present an alternative to the computationally intensive complex steerable pyramid for motion magnification, the Riesz formulation contains significant noise, and motion magnification still presents large amounts of data that cannot be quickly assessed by the human eye. Thus, user-friendly software is presented for quickly identifying structural response through optical flow and phase visualization in both Python and MATLAB.

  8. Bad-good constraints on a polarity correspondence account for the spatial-numerical association of response codes (SNARC) and markedness association of response codes (MARC) effects.

    PubMed

    Leth-Steensen, Craig; Citta, Richie

    2016-01-01

    Performance in numerical classification tasks involving either parity or magnitude judgements is quicker when small numbers are mapped onto a left-sided response and large numbers onto a right-sided response than for the opposite mapping (i.e., the spatial-numerical association of response codes or SNARC effect). Recent research by Gevers et al. [Gevers, W., Santens, S., Dhooge, E., Chen, Q., Van den Bossche, L., Fias, W., & Verguts, T. (2010). Verbal-spatial and visuospatial coding of number-space interactions. Journal of Experimental Psychology: General, 139, 180-190] suggests that this effect also arises for vocal "left" and "right" responding, indicating that verbal-spatial coding has a role to play in determining it. Another presumably verbal-based, spatial-numerical mapping phenomenon is the linguistic markedness association of response codes (MARC) effect whereby responding in parity tasks is quicker when odd numbers are mapped onto left-sided responses and even numbers onto right-sided responses. A recent account of both the SNARC and MARC effects is based on the polarity correspondence principle [Proctor, R. W., & Cho, Y. S. (2006). Polarity correspondence: A general principle for performance of speeded binary classification tasks. Psychological Bulletin, 132, 416-442]. This account assumes that stimulus and response alternatives are coded along any number of dimensions in terms of - and + polarities with quicker responding when the polarity codes for the stimulus and the response correspond. In the present study, even-odd parity judgements were made using either "left" and "right" or "bad" and "good" vocal responses. Results indicated that a SNARC effect was indeed present for the former type of vocal responding, providing further evidence for the sufficiency of the verbal-spatial coding account for this effect. However, the decided lack of an analogous SNARC-like effect in the results for the latter type of vocal responding provides an important constraint on the presumed generality of the polarity correspondence account. On the other hand, the presence of robust MARC effects for "bad" and "good" but not "left" and "right" vocal responses is consistent with the view that such effects are due to conceptual associations between semantic codes for odd-even and bad-good (but not necessarily left-right).

  9. 41 CFR 101-26.503 - Multiple award schedule purchases made by GSA supply distribution facilities.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... facilities are responsible for quickly and economically providing customers with frequently needed common-use... is an important way in which GSA supply distribution facilities meet this responsibility. [60 FR...

  10. The 6 "ws" of rapid response systems: best practices for improving development, implementation, and evaluation.

    PubMed

    Lazzara, Elizabeth H; Benishek, Lauren E; Sonesh, Shirley C; Patzer, Brady; Robinson, Patricia; Wallace, Ruth; Salas, Eduardo

    2014-01-01

    Delays in care have been cited as one of the primary contributors of preventable mortality; thus, quality patient safety is often contingent upon the delivery of timely clinical care. Rapid response systems (RRSs) have been touted as one mechanism to improve the ability of suitable staff to respond to deteriorating patients quickly and appropriately. Rapid response systems are defined as highly skilled individual(s) who mobilize quickly to provide medical care in response to clinical deterioration. While there is mounting evidence that RRSs are a valid strategy for managing obstetric emergencies, reducing adverse events, and improving patient safety, there remains limited insight into the practices underlying the development and execution of these systems. Therefore, the purpose of this article was to synthesize the literature and answer the primary questions necessary for successfully developing, implementing, and evaluating RRSs within inpatient settings-the Who, What, When, Where, Why, and How of RRSs.

  11. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Akyol, Bora A.; Allwardt, Craig H.; Beech, Zachary W.

    VOLTTRON is a flexible, reliable, and scalable platform for distributed control and sensing. VOLTTRON serves in four primary roles: •A reference platform for researchers to quickly develop control applications for transactive energy. •A reference platform with flexible data store support for energy analytics applications either in academia or in commercial enterprise. •A platform from which commercial enterprise can develop products without license issues and easily integrate into their product line. •An accelerator to drive industry adoption of transactive energy and advanced building energy analytics. Pacific Northwest National Laboratory, with funding from the U.S. Department of Energy’s Building Technologies Office, developedmore » and maintains VOLTTRON as an open-source community project. VOLTTRON source code includes agent execution software; agents that perform critical services that enable and enhance VOLTTRON functionality; and numerous agents that utilize the platform to perform a specific function (fault detection, demand response, etc.). The platform supports energy, operational, and financial transactions between networked entities (equipment, organizations, buildings, grid, etc.) and enhance the control infrastructure of existing buildings through the use of open-source device communication, control protocols, and integrated analytics.« less

  12. Update on Integrated Optical Design Analyzer

    NASA Technical Reports Server (NTRS)

    Moore, James D., Jr.; Troy, Ed

    2003-01-01

    Updated information on the Integrated Optical Design Analyzer (IODA) computer program has become available. IODA was described in Software for Multidisciplinary Concurrent Optical Design (MFS-31452), NASA Tech Briefs, Vol. 25, No. 10 (October 2001), page 8a. To recapitulate: IODA facilitates multidisciplinary concurrent engineering of highly precise optical instruments. The architecture of IODA was developed by reviewing design processes and software in an effort to automate design procedures. IODA significantly reduces design iteration cycle time and eliminates many potential sources of error. IODA integrates the modeling efforts of a team of experts in different disciplines (e.g., optics, structural analysis, and heat transfer) working at different locations and provides seamless fusion of data among thermal, structural, and optical models used to design an instrument. IODA is compatible with data files generated by the NASTRAN structural-analysis program and the Code V (Registered Trademark) optical-analysis program, and can be used to couple analyses performed by these two programs. IODA supports multiple-load-case analysis for quickly accomplishing trade studies. IODA can also model the transient response of an instrument under the influence of dynamic loads and disturbances.

  13. A team approach in palliative care: enhancing outcomes.

    PubMed

    Schrader, Susan L; Horner, Arlene; Eidsness, LuAnn; Young, Sandy; Wright, Chris; Robinson, Michael

    2002-07-01

    While most Americans envision a "good death" as one occurring quickly and painlessly at home surrounded by loved ones, many people do not die in this fashion. Palliative care focuses on holistic treatment of patients whose disease is not responsive to curative treatment, and strives to improve quality of life for patients and families at end-of-life (EOL). This hospital-based study examines the extent to which a palliative care consultant team makes a difference in EOL for patients and families. Data were collected from a convenience sample of 50 hospitalized patients referred to an interdisciplinary palliative care consulting team at a South Dakota tertiary hospital during 2001. Various palliative care interventions were introduced during the course of hospitalization, and data were collected two days later to see if quality of life had improved. Statistically significant improvements were found in pain levels, non-pain symptom management, numerous psychosocial measures of quality of life, change in code status, and perceptions of communication and treatment during hospitalization. The study demonstrates that consultations with a palliative care team are beneficial and enhance the EOL experience for patients and families.

  14. The Chandra Monitoring System

    NASA Astrophysics Data System (ADS)

    Wolk, S. J.; Petreshock, J. G.; Allen, P.; Bartholowmew, R. T.; Isobe, T.; Cresitello-Dittmar, M.; Dewey, D.

    The NASA Great Observatory Chandra was launched July 23, 1999 aboard the space shuttle Columbia. The Chandra Science Center (CXC) runs a monitoring and trends analysis program to maximize the science return from this mission. At the time of the launch, the monitoring portion of this system was in place. The system is a collection of multiple threads and programming methodologies acting cohesively. Real-time data are passed to the CXC. Our real-time tool, ACORN (A Comprehensive object-ORiented Necessity), performs limit checking of performance related hardware. Chandra is in ground contact less than 3 hours a day, so the bulk of the monitoring must take place on data dumped by the spacecraft. To do this, we have written several tools which run off of the CXC data system pipelines. MTA_MONITOR_STATIC, limit checks FITS files containing hardware data. MTA_EVENT_MON and MTA_GRAT_MON create quick look data for the focal place instruments and the transmission gratings. When instruments violate their operational limits, the responsible scientists are notified by email and problem tracking is initiated. Output from all these codes is distributed to CXC scientists via HTML interface.

  15. Using framework-based synthesis for conducting reviews of qualitative studies.

    PubMed

    Dixon-Woods, Mary

    2011-04-14

    Framework analysis is a technique used for data analysis in primary qualitative research. Recent years have seen its being adapted to conduct syntheses of qualitative studies. Framework-based synthesis shows considerable promise in addressing applied policy questions. An innovation in the approach, known as 'best fit' framework synthesis, has been published in BMC Medical Research Methodology this month. It involves reviewers in choosing a conceptual model likely to be suitable for the question of the review, and using it as the basis of their initial coding framework. This framework is then modified in response to the evidence reported in the studies in the reviews, so that the final product is a revised framework that may include both modified factors and new factors that were not anticipated in the original model. 'Best fit' framework-based synthesis may be especially suitable in addressing urgent policy questions where the need for a more fully developed synthesis is balanced by the need for a quick answer. Please see related article: http://www.biomedcentral.com/1471-2288/11/29.

  16. 2015 QuickCompass of Sexual Assult-Related Responders: Statistical Methodology Report

    DTIC Science & Technology

    2016-02-01

    2015 QuickCompass of Sexual Assault Prevention and Response- Related Responders Statistical Methodology Report Additional copies of this report...from: http://www.dtic.mil/ Ask for report by ADA630235 DMDC Report No. 2015-039 February 2016 2015 QUICKCOMPASS OF SEXUAL ASSAULT PREVENTION...Defense Research, Surveys, and Statistics Center (RSSC) 4800 Mark Center Drive , Suite 04E25-01, Alexandria, VA 22350-4000 ii Acknowledgments

  17. Applying the Verona coding definitions of emotional sequences (VR-CoDES) to code medical students' written responses to written case scenarios: Some methodological and practical considerations.

    PubMed

    Ortwein, Heiderose; Benz, Alexander; Carl, Petra; Huwendiek, Sören; Pander, Tanja; Kiessling, Claudia

    2017-02-01

    To investigate whether the Verona Coding Definitions of Emotional Sequences to code health providers' responses (VR-CoDES-P) can be used for assessment of medical students' responses to patients' cues and concerns provided in written case vignettes. Student responses in direct speech to patient cues and concerns were analysed in 21 different case scenarios using VR-CoDES-P. A total of 977 student responses were available for coding, and 857 responses were codable with the VR-CoDES-P. In 74.6% of responses, the students used either a "reducing space" statement only or a "providing space" statement immediately followed by a "reducing space" statement. Overall, the most frequent response was explicit information advice (ERIa) followed by content exploring (EPCEx) and content acknowledgement (EPCAc). VR-CoDES-P were applicable to written responses of medical students when they were phrased in direct speech. The application of VR-CoDES-P is reliable and feasible when using the differentiation of "providing" and "reducing space" responses. Communication strategies described by students in non-direct speech were difficult to code and produced many missings. VR-CoDES-P are useful for analysis of medical students' written responses when focusing on emotional issues. Students need precise instructions for their response in the given test format. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  18. Heat shock factor-1 intertwines insulin/IGF-1, TGF-β and cGMP signaling to control development and aging.

    PubMed

    Barna, János; Princz, Andrea; Kosztelnik, Mónika; Hargitai, Balázs; Takács-Vellai, Krisztina; Vellai, Tibor

    2012-11-01

    Temperature affects virtually all cellular processes. A quick increase in temperature challenges the cells to undergo a heat shock response to maintain cellular homeostasis. Heat shock factor-1 (HSF-1) functions as a major player in this response as it activates the transcription of genes coding for molecular chaperones (also called heat shock proteins) that maintain structural integrity of proteins. However, the mechanisms by which HSF-1 adjusts fundamental cellular processes such as growth, proliferation, differentiation and aging to the ambient temperature remain largely unknown. We demonstrate here that in Caenorhabditis elegans HSF-1 represses the expression of daf-7 encoding a TGF-β (transforming growth factor-beta) ligand, to induce young larvae to enter the dauer stage, a developmentally arrested, non-feeding, highly stress-resistant, long-lived larval form triggered by crowding and starvation. Under favorable conditions, HSF-1 is inhibited by crowding pheromone-sensitive guanylate cyclase/cGMP (cyclic guanosine monophosphate) and systemic nutrient-sensing insulin/IGF-1 (insulin-like growth factor-1) signaling; loss of HSF-1 activity allows DAF-7 to promote reproductive growth. Thus, HSF-1 interconnects the insulin/IGF-1, TGF-β and cGMP neuroendocrine systems to control development and longevity in response to diverse environmental stimuli. Furthermore, HSF-1 upregulates another TGF-β pathway-interacting gene, daf-9/cytochrome P450, thereby fine-tuning the decision between normal growth and dauer formation. Together, these results provide mechanistic insight into how temperature, nutrient availability and population density coordinately influence development, lifespan, behavior and stress response through HSF-1.

  19. Quick-low-density parity check and dynamic threshold voltage optimization in 1X nm triple-level cell NAND flash memory with comprehensive analysis of endurance, retention-time, and temperature variation

    NASA Astrophysics Data System (ADS)

    Doi, Masafumi; Tokutomi, Tsukasa; Hachiya, Shogo; Kobayashi, Atsuro; Tanakamaru, Shuhei; Ning, Sheyang; Ogura Iwasaki, Tomoko; Takeuchi, Ken

    2016-08-01

    NAND flash memory’s reliability degrades with increasing endurance, retention-time and/or temperature. After a comprehensive evaluation of 1X nm triple-level cell (TLC) NAND flash, two highly reliable techniques are proposed. The first proposal, quick low-density parity check (Quick-LDPC), requires only one cell read in order to accurately estimate a bit-error rate (BER) that includes the effects of temperature, write and erase (W/E) cycles and retention-time. As a result, 83% read latency reduction is achieved compared to conventional AEP-LDPC. Also, W/E cycling is extended by 100% compared with conventional Bose-Chaudhuri-Hocquenghem (BCH) error-correcting code (ECC). The second proposal, dynamic threshold voltage optimization (DVO) has two parts, adaptive V Ref shift (AVS) and V TH space control (VSC). AVS reduces read error and latency by adaptively optimizing the reference voltage (V Ref) based on temperature, W/E cycles and retention-time. AVS stores the optimal V Ref’s in a table in order to enable one cell read. VSC further improves AVS by optimizing the voltage margins between V TH states. DVO reduces BER by 80%.

  20. A polygalacturonase-inhibiting protein with a role in pea defence against the cyst nematode Heterodera goettingiana.

    PubMed

    Veronico, Pasqua; Melillo, M Teresa; Saponaro, Concetta; Leonetti, Paola; Picardi, Ernesto; Jones, John T

    2011-04-01

    A cDNA of 312 bp, similar to polygalacturonase-inhibiting proteins (PGIPs), was isolated by cDNA-amplified fragment length polymorphism (cDNA-AFLP) from pea roots infected with the cyst nematode Heterodera goettingiana. The deduced amino acid sequence obtained from the complete Pspgip1 coding sequence was very similar to PGIPs described from several other plant species, and was identical in both MG103738 and Progress 9 genotypes, resistant and susceptible to H. goettingiana, respectively. Reverse transcription-polymerase chain reaction (RT-PCR) expression analysis revealed the differential regulation of the Pspgip1 gene in the two genotypes in response to wounding and nematode challenge. Mechanical wounding induced Pspgip1 expression in MG103738 within 8 h, but this response was delayed in Progress 9. In contrast, the response to nematode infection was more complex. The transcription of Pspgip1 was triggered rapidly in both genotypes, but the expression level returned to levels observed in uninfected plants more quickly in susceptible than in resistant roots. In addition, in situ hybridization showed that Pspgip1 was expressed in the cortical cells damaged as a result of nematode invasion in both genotypes. However, it was specifically localized in the cells bordering the nematode-induced syncytia in resistant roots. This suggests a role for this gene in counteracting nematode establishment inside the root. © 2010 THE AUTHORS. MOLECULAR PLANT PATHOLOGY © 2010 BSPP AND BLACKWELL PUBLISHING LTD.

  1. Quality improvement utilizing in-situ simulation for a dual-hospital pediatric code response team.

    PubMed

    Yager, Phoebe; Collins, Corey; Blais, Carlene; O'Connor, Kathy; Donovan, Patricia; Martinez, Maureen; Cummings, Brian; Hartnick, Christopher; Noviski, Natan

    2016-09-01

    Given the rarity of in-hospital pediatric emergency events, identification of gaps and inefficiencies in the code response can be difficult. In-situ, simulation-based medical education programs can identify unrecognized systems-based challenges. We hypothesized that developing an in-situ, simulation-based pediatric emergency response program would identify latent inefficiencies in a complex, dual-hospital pediatric code response system and allow rapid intervention testing to improve performance before implementation at an institutional level. Pediatric leadership from two hospitals with a shared pediatric code response team employed the Institute for Healthcare Improvement's (IHI) Breakthrough Model for Collaborative Improvement to design a program consisting of Plan-Do-Study-Act cycles occurring in a simulated environment. The objectives of the program were to 1) identify inefficiencies in our pediatric code response; 2) correlate to current workflow; 3) employ an iterative process to test quality improvement interventions in a safe environment; and 4) measure performance before actual implementation at the institutional level. Twelve dual-hospital, in-situ, simulated, pediatric emergencies occurred over one year. The initial simulated event allowed identification of inefficiencies including delayed provider response, delayed initiation of cardiopulmonary resuscitation (CPR), and delayed vascular access. These gaps were linked to process issues including unreliable code pager activation, slow elevator response, and lack of responder familiarity with layout and contents of code cart. From first to last simulation with multiple simulated process improvements, code response time for secondary providers coming from the second hospital decreased from 29 to 7 min, time to CPR initiation decreased from 90 to 15 s, and vascular access obtainment decreased from 15 to 3 min. Some of these simulated process improvements were adopted into the institutional response while others continue to be trended over time for evidence that observed changes represent a true new state of control. Utilizing the IHI's Breakthrough Model, we developed a simulation-based program to 1) successfully identify gaps and inefficiencies in a complex, dual-hospital, pediatric code response system and 2) provide an environment in which to safely test quality improvement interventions before institutional dissemination. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  2. Disaster Response and Planning for Libraries.

    ERIC Educational Resources Information Center

    Kahn, Miriam B.

    Providing a customized disaster response plan to assist libraries in quick recovery, this resource also outlines step to minimize damage and protect materials before trouble strikes. The first section of the book, "Response," contains information how to handle small jobs in-house and suggestions for working with contractors--with an…

  3. Reinforcement Sensitivity and Responsiveness to Performance Feedback: A Preliminary Investigation

    ERIC Educational Resources Information Center

    Lovett, Benjamin J.; Eckert, Tanya L.

    2009-01-01

    Variability in responsiveness to academic interventions is a common phenomenon in school psychology practice, but the variables associated with this responsiveness are not well understood. Reinforcement sensitivity, a generalized tendency to learn quickly in reward contingency situations, is one variable for increased understanding. In the present…

  4. The response of phospholipid-encapsulated microbubbles to chirp-coded excitation: Implications for high-frequency nonlinear imaging

    PubMed Central

    Shekhar, Himanshu; Doyley, Marvin M.

    2013-01-01

    The current excitation strategy for harmonic and subharmonic imaging (HI and SHI) uses short sine-bursts. However, alternate pulsing strategies may be useful for enhancing nonlinear emissions from ultrasound contrast agents. The goal of this study was to corroborate the hypothesis that chirp-coded excitation can improve the performance of high-frequency HI and SHI. A secondary goal was to understand the mechanisms that govern the response of ultrasound contrast agents to chirp-coded and sine-burst excitation schemes. Numerical simulations and acoustic measurements were conducted to evaluate the response of a commercial contrast agent (Targestar-P®) to chirp-coded and sine-burst excitation (10 MHz frequency, peak pressures 290 kPa). The results of the acoustic measurements revealed an improvement in signal-to-noise ratio by 4 to 14 dB, and a two- to threefold reduction in the subharmonic threshold with chirp-coded excitation. Simulations conducted with the Marmottant model suggest that an increase in expansion-dominated radial excursion of microbubbles was the mechanism responsible for the stronger nonlinear response. Additionally, chirp-coded excitation detected the nonlinear response for a wider range of agent concentrations than sine-bursts. Therefore, chirp-coded excitation could be a viable approach for enhancing the performance of HI and SHI. PMID:23654417

  5. The response of phospholipid-encapsulated microbubbles to chirp-coded excitation: implications for high-frequency nonlinear imaging.

    PubMed

    Shekhar, Himanshu; Doyley, Marvin M

    2013-05-01

    The current excitation strategy for harmonic and subharmonic imaging (HI and SHI) uses short sine-bursts. However, alternate pulsing strategies may be useful for enhancing nonlinear emissions from ultrasound contrast agents. The goal of this study was to corroborate the hypothesis that chirp-coded excitation can improve the performance of high-frequency HI and SHI. A secondary goal was to understand the mechanisms that govern the response of ultrasound contrast agents to chirp-coded and sine-burst excitation schemes. Numerical simulations and acoustic measurements were conducted to evaluate the response of a commercial contrast agent (Targestar-P(®)) to chirp-coded and sine-burst excitation (10 MHz frequency, peak pressures 290 kPa). The results of the acoustic measurements revealed an improvement in signal-to-noise ratio by 4 to 14 dB, and a two- to threefold reduction in the subharmonic threshold with chirp-coded excitation. Simulations conducted with the Marmottant model suggest that an increase in expansion-dominated radial excursion of microbubbles was the mechanism responsible for the stronger nonlinear response. Additionally, chirp-coded excitation detected the nonlinear response for a wider range of agent concentrations than sine-bursts. Therefore, chirp-coded excitation could be a viable approach for enhancing the performance of HI and SHI.

  6. The acquisition of simple associations as observed in color-word contingency learning.

    PubMed

    Lin, Olivia Y-H; MacLeod, Colin M

    2018-01-01

    Three experiments investigated the learning of simple associations in a color-word contingency task. Participants responded manually to the print colors of 3 words, with each word associated strongly to 1 of the 3 colors and weakly to the other 2 colors. Despite the words being irrelevant, response times to high-contingency stimuli and to low-contingency stimuli quickly diverged. This high-low difference remained quite constant over successive blocks of trials, evidence of stable contingency learning. Inclusion of a baseline condition-an item having no color-word contingency-permitted separation of the contingency learning effect into 2 components: a cost due to low contingency and a benefit due to high contingency. Both cost and benefit were quick to acquire, quick to extinguish, and quick to reacquire. The color-word contingency task provides a simple way to directly study the learning of associations. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  7. Design of protein-responsive micro-sized hydrogels for self-regulating microfluidic systems

    NASA Astrophysics Data System (ADS)

    Hirayama, Mayu; Tsuruta, Kazuhiro; Kawamura, Akifumi; Ohara, Masayuki; Shoji, Kan; Kawano, Ryuji; Miyata, Takashi

    2018-03-01

    Diagnosis sensors using micro-total analysis systems (µ-TAS) have been developed for detecting target biomolecules such as proteins and saccharides because they are signal biomolecules for monitoring body conditions and diseases. In this study, biomolecularly stimuli-responsive micro-sized hydrogels that exhibited quick shrinkage in response to lectin concanavalinA (ConA) were prepared in a microchannel by photopolymerization using a fluorescence microscope. In preparing the micro-size hydrogels, glycosyloxyethyl methacrylate (GEMA) as a ligand monomer was copolymerized with a crosslinker in the presence of template ConA in molecular imprinting. The ConA-imprinted micro-hydrogel showed greater shrinkage in response to target ConA than nonimprinted micro-hydrogel. When a buffer solution was switched to an aqueous ConA solution in the Y-shaped microchannel, the flow rates changed quickly because of the responsive shrinkage of the micro-hydrogel prepared in the microchannel. These results suggest that the ConA-imprinted micro-hydrogel acted as a self-regulated microvalve in microfluidic systems.

  8. TEC data ingestion into IRI and NeQuick over the antarctic region

    NASA Astrophysics Data System (ADS)

    Nava, Bruno; Pezzopane, Michael; Radicella, Sandro M.; Scotto, Carlo; Pietrella, Marco; Migoya Orue, Yenca; Alazo Cuartas, Katy; Kashcheyev, Anton

    2016-07-01

    In the present work a comparative analysis to evaluate the IRI and NeQuick 2 models capabilities in reproducing the ionospheric behaviour over the Antarctic Region has been performed. A technique to adapt the two models to GNSS-derived vertical Total Electron Content (TEC) has been therefore implemented to retrieve the 3-D ionosphere electron density at specific locations where ionosonde data were available. In particular, the electron density profiles used in this study have been provided in the framework of the AUSPICIO (AUtomatic Scaling of Polar Ionograms and Cooperative Ionospheric Observations) project applying the Adaptive Ionospheric Profiler (AIP) to ionograms recorded at eight selected mid, high-latitude and polar ionosondes. The relevant GNSS-derived vertical TEC values have been obtained from the Global Ionosphere Maps (GIM) produced by the Center for Orbit Determination in Europe (CODE). The effectiveness of the IRI and NeQuick 2 in reconstructing the ionosphere electron density at the given locations and epochs has been primarily assessed in terms of statistical comparison between experimental and model-retrieved peak parameters values (foF2 and hmF2). The analysis results indicate that in general the models are equivalent in their ability to reproduce the critical frequency of the F2 layer and they also tend to overestimate the height of the peak electron density, especially during high solar activity periods. Nevertheless this tendency is more noticeable in NeQuick 2 than in IRI. For completeness, the statistics indicating the models bottomside reconstruction capabilities, computed as height integrated electron density profile mismodeling, will also be discussed.

  9. Grid Generation Techniques Utilizing the Volume Grid Manipulator

    NASA Technical Reports Server (NTRS)

    Alter, Stephen J.

    1998-01-01

    This paper presents grid generation techniques available in the Volume Grid Manipulation (VGM) code. The VGM code is designed to manipulate existing line, surface and volume grids to improve the quality of the data. It embodies an easy to read rich language of commands that enables such alterations as topology changes, grid adaption and smoothing. Additionally, the VGM code can be used to construct simplified straight lines, splines, and conic sections which are common curves used in the generation and manipulation of points, lines, surfaces and volumes (i.e., grid data). These simple geometric curves are essential in the construction of domain discretizations for computational fluid dynamic simulations. By comparison to previously established methods of generating these curves interactively, the VGM code provides control of slope continuity and grid point-to-point stretchings as well as quick changes in the controlling parameters. The VGM code offers the capability to couple the generation of these geometries with an extensive manipulation methodology in a scripting language. The scripting language allows parametric studies of a vehicle geometry to be efficiently performed to evaluate favorable trends in the design process. As examples of the powerful capabilities of the VGM code, a wake flow field domain will be appended to an existing X33 Venturestar volume grid; negative volumes resulting from grid expansions to enable flow field capture on a simple geometry, will be corrected; and geometrical changes to a vehicle component of the X33 Venturestar will be shown.

  10. Ethical Issues and Codes of Ethics: Views of Adult Education Practitioners in Canada and the United States.

    ERIC Educational Resources Information Center

    Gordon, Wanda; Sork, Thomas J.

    2001-01-01

    Replicating an Indiana study, 261 responses from British Columbia adult educators revealed a high degree of support for codes of ethics and identified ethical dilemmas in practice. Half currently operated under a code. Responses to whether codes should have a regulatory function were mixed. (Contains 44 references.) (SK)

  11. Agent-Based Phytoplankton Models of Cellular and Population Processes: Fostering Individual-Based Learning in Undergraduate Research

    NASA Astrophysics Data System (ADS)

    Berges, J. A.; Raphael, T.; Rafa Todd, C. S.; Bate, T. C.; Hellweger, F. L.

    2016-02-01

    Engaging undergraduate students in research projects that require expertise in multiple disciplines (e.g. cell biology, population ecology, and mathematical modeling) can be challenging because they have often not developed the expertise that allows them to participate at a satisfying level. Use of agent-based modeling can allow exploration of concepts at more intuitive levels, and encourage experimentation that emphasizes processes over computational skills. Over the past several years, we have involved undergraduate students in projects examining both ecological and cell biological aspects of aquatic microbial biology, using the freely-downloadable, agent-based modeling environment NetLogo (https://ccl.northwestern.edu/netlogo/). In Netlogo, actions of large numbers of individuals can be simulated, leading to complex systems with emergent behavior. The interface features appealing graphics, monitors, and control structures. In one example, a group of sophomores in a BioMathematics program developed an agent-based model of phytoplankton population dynamics in a pond ecosystem, motivated by observed macroscopic changes in cell numbers (due to growth and death), and driven by responses to irradiance, temperature and a limiting nutrient. In a second example, junior and senior undergraduates conducting Independent Studies created a model of the intracellular processes governing stress and cell death for individual phytoplankton cells (based on parameters derived from experiments using single-cell culturing and flow cytometry), and then this model was embedded in the agents in the pond ecosystem model. In our experience, students with a range of mathematical abilities learned to code quickly and could use the software with varying degrees of sophistication, for example, creation of spatially-explicit two and three-dimensional models. Skills developed quickly and transferred readily to other platforms (e.g. Matlab).

  12. Spectroscopic investigation of carbon migration with tungsten walls in ASDEX Upgrade

    NASA Astrophysics Data System (ADS)

    Kallenbach, A.; Dux, R.; Harhausen, J.; Maggi, C. F.; Neu, R.; Pütterich, T.; Rohde, V.; Schmid, K.; Wolfrum, E.; ASDEX Upgrade Team

    2007-06-01

    Spectroscopic measurements of carbon fluxes in the mainly tungsten-coated ASDEX Upgrade tokamak are analysed with a particle transport and migration code. The transport parameters for deuterium and carbon are calibrated against flux measurements for different experimental conditions. Additional information is obtained from the re-appearance time of carbon after a boronisation. The code reproduces the experimental finding that despite a 85% (2006 campaign) tungsten coverage of the primary PFCs, the carbon concentration in the core and edge plasma is reduced by about a factor 2 only compared to full carbon PFCs. This behaviour is explained by the strong main chamber recycling of carbon in comparison with the loss flux to the inner divertor. The quick recovery of the carbon level in the plasma after a boronisation is explained by carbon influx from the outer divertor.

  13. Introducing a New Software for Geodetic Analysis

    NASA Astrophysics Data System (ADS)

    Hjelle, G. A.; Dähnn, M.; Fausk, I.; Kirkvik, A. S.; Mysen, E.

    2016-12-01

    At the Norwegian Mapping Authority, we are currently developing Where, a newsoftware for geodetic analysis. Where is built on our experiences with theGeosat software, and will be able to analyse and combine data from VLBI, SLR,GNSS and DORIS. The software is mainly written in Python which has proved veryfruitful. The code is quick to write and the architecture is easily extendableand maintainable. The Python community provides a rich eco-system of tools fordoing data-analysis, including effective data storage and powerfulvisualization. Python interfaces well with other languages so that we can easilyreuse existing, well-tested code like the SOFA and IERS libraries. This presentation will show some of the current capabilities of Where,including benchmarks against other software packages. In addition we will reporton some simple investigations we have done using the software, and outline ourplans for further progress.

  14. Automatic Generation of OpenMP Directives and Its Application to Computational Fluid Dynamics Codes

    NASA Technical Reports Server (NTRS)

    Yan, Jerry; Jin, Haoqiang; Frumkin, Michael; Yan, Jerry (Technical Monitor)

    2000-01-01

    The shared-memory programming model is a very effective way to achieve parallelism on shared memory parallel computers. As great progress was made in hardware and software technologies, performance of parallel programs with compiler directives has demonstrated large improvement. The introduction of OpenMP directives, the industrial standard for shared-memory programming, has minimized the issue of portability. In this study, we have extended CAPTools, a computer-aided parallelization toolkit, to automatically generate OpenMP-based parallel programs with nominal user assistance. We outline techniques used in the implementation of the tool and discuss the application of this tool on the NAS Parallel Benchmarks and several computational fluid dynamics codes. This work demonstrates the great potential of using the tool to quickly port parallel programs and also achieve good performance that exceeds some of the commercial tools.

  15. Flexible and evolutionary optical access networks

    NASA Astrophysics Data System (ADS)

    Hsueh, Yu-Li

    Passive optical networks (PONs) are promising solutions that will open the first-mile bottleneck. Current PONs employ time division multiplexing (TDM) to share bandwidth among users, leading to low cost but limited capacity. In the future, wavelength division multiplexing (WDM) technologies will be deployed to achieve high performance. This dissertation describes several advanced technologies to enhance PON systems. A spectral shaping line coding scheme is developed to allow a simple and cost-effective overlay of high data-rate services in existing PONs, leaving field-deployed fibers and existing services untouched. Spectral shapes of coded signals can be manipulated to adapt to different systems. For a specific tolerable interference level, the optimal line code can be found which maximizes the data throughput. Experiments are conducted to demonstrate and compare several optimized line codes. A novel PON employing dynamic wavelength allocation to provide bandwidth sharing across multiple physical PONs is designed and experimentally demonstrated. Tunable lasers, arrayed waveguide gratings, and coarse/fine filtering combine to create a flexible optical access solution. The network's excellent scalability can bridge the gap between conventional TDM PONs and WDM PONs. Scheduling algorithms with quality of service support are also investigated. Simulation results show that the proposed architecture exhibits significant performance gain over conventional PON systems. Streaming video transmission is demonstrated on the prototype experimental testbed. The powerful architecture is a promising candidate for next-generation optical access networks. A new CDR circuit for receiving the bursty traffic in PONs is designed and analyzed. It detects data transition edges upon arrival of the data burst and quickly selects the best clock phase by a control logic circuit. Then, an analog delay-locked loop (DLL) keeps track of data transitions and removes phase errors throughout the burst. The combination of the fast phase detection mechanism and a feedback loop based on DLL allows both fast response and manageable jitter performance in the burst-mode application. A new efficient numerical algorithm is developed to analyze holey optical fibers. The algorithm has been verified against experimental data, and is exploited to design holey optical fibers optimized for the discrete Raman amplification.

  16. The PROMIS physical function correlates with the QuickDASH in patients with upper extremity illness.

    PubMed

    Overbeek, Celeste L; Nota, Sjoerd P F T; Jayakumar, Prakash; Hageman, Michiel G; Ring, David

    2015-01-01

    To assess disability more efficiently with less burden on the patient, the National Institutes of Health has developed the Patient Reported Outcomes Measurement Information System (PROMIS) Physical Function-an instrument based on item response theory and using computer adaptive testing (CAT). Initially, upper and lower extremity disabilities were not separated and we were curious if the PROMIS Physical Function CAT could measure upper extremity disability and the Quick Disability of Arm, Shoulder and Hand (QuickDASH). We aimed to find correlation between the PROMIS Physical Function and the QuickDASH questionnaires in patients with upper extremity illness. Secondarily, we addressed whether the PROMIS Physical Function and QuickDASH correlate with the PROMIS Depression CAT and PROMIS Pain Interference CAT instruments. Finally, we assessed factors associated with QuickDASH and PROMIS Physical Function in multivariable analysis. A cohort of 93 outpatients with upper extremity illnesses completed the QuickDASH and three PROMIS CAT questionnaires: Physical Function, Pain Interference, and Depression. Pain intensity was measured with an 11-point ordinal measure (0-10 numeric rating scale). Correlation between PROMIS Physical Function and the QuickDASH was assessed. Factors that correlated with the PROMIS Physical Function and QuickDASH were assessed in multivariable regression analysis after initial bivariate analysis. There was a moderate correlation between the PROMIS Physical Function and the QuickDASH questionnaire (r=-0.55, p<0.001). Greater disability as measured with the PROMIS and QuickDASH correlated most strongly with PROMIS Depression (r=-0.35, p<0.001 and r=0.34, p<0.001 respectively) and Pain Interference (r=-0.51, p<0.001 and r=0.74, p<0.001 respectively). The factors accounting for the variability in PROMIS scores are comparable to those for the QuickDASH except that the PROMIS Physical Function is influenced by other pain conditions while the QuickDASH is not. The PROMIS Physical Function instrument may be used as an upper extremity disability measure, as it correlates with the QuickDASH questionnaire, and both instruments are influenced most strongly by the degree to which pain interferes with achieving goals. Level III, diagnostic study. See the Instructions for Authors for a complete description of levels of evidence.

  17. CHEETAH: A next generation thermochemical code

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fried, L.; Souers, P.

    1994-11-01

    CHEETAH is an effort to bring the TIGER thermochemical code into the 1990s. A wide variety of improvements have been made in Version 1.0. We have improved the robustness and ease of use of TIGER. All of TIGER`s solvers have been replaced by new algorithms. We find that CHEETAH solves a wider variety of problems with no user intervention (e.g. no guesses for the C-J state) than TIGER did. CHEETAH has been made simpler to use than TIGER; typical use of the code occurs with the new standard run command. CHEETAH will make the use of thermochemical codes more attractivemore » to practical explosive formulators. We have also made an extensive effort to improve over the results of TIGER. CHEETAH`s version of the BKW equation of state (BKWC) is able to accurately reproduce energies from cylinder tests; something that other BKW parameter sets have been unable to do. Calculations performed with BKWC execute very quickly; typical run times are under 10 seconds on a workstation. In the future we plan to improve the underlying science in CHEETAH. More accurate equations of state will be used in the gas and the condensed phase. A kinetics capability will be added to the code that will predict reaction zone thickness. Further ease of use features will eventually be added; an automatic formulator that adjusts concentrations to match desired properties is planned.« less

  18. Axial and Centrifugal Compressor Mean Line Flow Analysis Method

    NASA Technical Reports Server (NTRS)

    Veres, Joseph P.

    2009-01-01

    This paper describes a method to estimate key aerodynamic parameters of single and multistage axial and centrifugal compressors. This mean-line compressor code COMDES provides the capability of sizing single and multistage compressors quickly during the conceptual design process. Based on the compressible fluid flow equations and the Euler equation, the code can estimate rotor inlet and exit blade angles when run in the design mode. The design point rotor efficiency and stator losses are inputs to the code, and are modeled at off design. When run in the off-design analysis mode, it can be used to generate performance maps based on simple models for losses due to rotor incidence and inlet guide vane reset angle. The code can provide an improved understanding of basic aerodynamic parameters such as diffusion factor, loading levels and incidence, when matching multistage compressor blade rows at design and at part-speed operation. Rotor loading levels and relative velocity ratio are correlated to the onset of compressor surge. NASA Stage 37 and the three-stage NASA 74-A axial compressors were analyzed and the results compared to test data. The code has been used to generate the performance map for the NASA 76-B three-stage axial compressor featuring variable geometry. The compressor stages were aerodynamically matched at off-design speeds by adjusting the variable inlet guide vane and variable stator geometry angles to control the rotor diffusion factor and incidence angles.

  19. Aviation System Analysis Capability (ASAC) Quick Response System (QRS) Test Report

    NASA Technical Reports Server (NTRS)

    Roberts, Eileen; Villani, James A.; Ritter, Paul

    1997-01-01

    This document is the Aviation System Analysis Capability (ASAC) Quick Response System (QRS) Test Report. The purpose of this document is to present the results of the QRS unit and system tests in support of the ASAC QRS development effort. This document contains an overview of the project background and scope, defines the QRS system and presents the additions made to the QRS this year, explains the assumptions, constraints, and approach used to conduct QRS Unit and System Testing, and presents the schedule used to perform QRS Testing. The document also presents an overview of the Logistics Management Institute (LMI) Test Facility and testing environment and summarizes the QRS Unit and System Test effort and results.

  20. Control Measures Used during Lymphogranuloma Venereum Outbreak, Europe

    PubMed Central

    Hulscher, Marlies E.J.L.; Vos, Dieuwke; van de Laar, Marita J.W.; Fenton, Kevin A.; van Steenbergen, Jim E.; van der Meer, Jos W.M.; Grol, Richard P.T.M.

    2008-01-01

    To assess the response to the reemergence of lymphogranuloma venereum, we conducted a cross-sectional survey by administering a structured questionnaire to representatives from 26 European countries. Responses were received from 18 countries. The ability to respond quickly and the measures used for outbreak detection and control varied. Evidence-based criteria were not consistently used to develop recommendations. We did not develop criteria to determine the effectiveness of the recommendations. The degree of preparedness for an unexpected outbreak, as well as the ability of countries to respond quickly to alerts, varied, which indicates weaknesses in the ability to control an outbreak. More guidance is needed to implement and evaluate control measures used during international outbreaks. PMID:18394274

  1. Thermal hydraulic-severe accident code interfaces for SCDAP/RELAP5/MOD3.2

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Coryell, E.W.; Siefken, L.J.; Harvego, E.A.

    1997-07-01

    The SCDAP/RELAP5 computer code is designed to describe the overall reactor coolant system thermal-hydraulic response, core damage progression, and fission product release during severe accidents. The code is being developed at the Idaho National Engineering Laboratory under the primary sponsorship of the Office of Nuclear Regulatory Research of the U.S. Nuclear Regulatory Commission. The code is the result of merging the RELAP5, SCDAP, and COUPLE codes. The RELAP5 portion of the code calculates the overall reactor coolant system, thermal-hydraulics, and associated reactor system responses. The SCDAP portion of the code describes the response of the core and associated vessel structures.more » The COUPLE portion of the code describes response of lower plenum structures and debris and the failure of the lower head. The code uses a modular approach with the overall structure, input/output processing, and data structures following the pattern established for RELAP5. The code uses a building block approach to allow the code user to easily represent a wide variety of systems and conditions through a powerful input processor. The user can represent a wide variety of experiments or reactor designs by selecting fuel rods and other assembly structures from a range of representative core component models, and arrange them in a variety of patterns within the thermalhydraulic network. The COUPLE portion of the code uses two-dimensional representations of the lower plenum structures and debris beds. The flow of information between the different portions of the code occurs at each system level time step advancement. The RELAP5 portion of the code describes the fluid transport around the system. These fluid conditions are used as thermal and mass transport boundary conditions for the SCDAP and COUPLE structures and debris beds.« less

  2. A code of ethics for nurse educators: revised.

    PubMed

    Rosenkoetter, Marlene M; Milstead, Jeri A

    2010-01-01

    Nurse educators have the responsibility of assisting students and their colleagues with understanding and practicing ethical conduct. There is an inherent responsibility to keep codes current and relevant for existing nursing practice. The code presented here is a revision of the Code of ethics for nurse educators originally published in 1983 and includes changes that are intended to provide for that relevancy.

  3. Developing a Machine-Supported Coding System for Constructed-Response Items in PISA. Research Report. ETS RR-17-47

    ERIC Educational Resources Information Center

    Yamamoto, Kentaro; He, Qiwei; Shin, Hyo Jeong; von Davier, Mattias

    2017-01-01

    Approximately a third of the Programme for International Student Assessment (PISA) items in the core domains (math, reading, and science) are constructed-response items and require human coding (scoring). This process is time-consuming, expensive, and prone to error as often (a) humans code inconsistently, and (b) coding reliability in…

  4. Orthogonal stimulus-response compatibility effects emerge even when the stimulus position is task irrelevant.

    PubMed

    Nishimura, Akio; Yokosawa, Kazuhiko

    2006-06-01

    The above-right/below-left mapping advantage with vertical stimuli and horizontal responses is known as the orthogonal stimulus-response compatibility (SRC) effect. We investigated whether the orthogonal SRC effect emerges with irrelevant stimulus dimensions. In Experiment 1, participants responded with a right or left key press to the colour of the stimulus presented above or below the fixation. We observed an above-right/below-left advantage (orthogonal Simon effect). In Experiment 2, we manipulated the polarity in the response dimension by varying the horizontal location of the response set. The orthogonal Simon effect decreased and even reversed as the left response code became more positive. This result provides evidence for the automatic activation of the positive and negative response codes by the corresponding positive and negative stimulus codes. These findings extended the orthogonal SRC effect based on coding asymmetry to an irrelevant stimulus dimension.

  5. A New Non-LTE Model based on Super Configurations

    NASA Astrophysics Data System (ADS)

    Bar-Shalom, A.; Klapisch, M.

    1996-11-01

    Non-LTE effects are vital for the simulation of radiation in hot plasmas involving even medium Z materials. However, the exceedingly large number of atomic energy levels forbids using a detailed collisional radiative model on-line in the hydrodynamic simulations. For this purpose, greatly simplified models are required. We implemented recently Busquet's model(M. Busquet, Phys. Fluids B, 5, 4191 (1993)) in NRL's RAD2D Hydro code in conservative form (M. Klapisch et al., Bull. Am. Phys. Soc., 40, 1806 (1995), and poster at this meeting.). This model is quick and the results make sense, but in the absence of precisely defined experiments, it is difficult to asses its accuracy. We present here a new collisional radiative model based on superconfigurations( A. Bar-Shalom, J. Oreg, J. F. Seely, U. Feldman, C. M. Brown, B. A. Hammel, R. W. Lee and C. A. Back, Phys. Rev. E, 52, 6686 (1995).), intended to be a benchmark for approximate models used in hydro-codes. It uses accurate rates from the HULLAC Code. Results for various elements will be presented and compared with RADIOM.

  6. World Energy Data System (WENDS). Volume X. Nuclear facility profiles, PO--ZA. [Brief tabulated information

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1979-06-01

    In this compendium each profile of a nuclear facility is a capsule summary of pertinent facts regarding that particular installation. The facilities described include the entire fuel cycle in the broadest sense, encompassing resource recovery through waste management. Power plants and all US facilities have been excluded. To facilitate comparison the profiles have been recorded in a standard format. Because of the breadth of the undertaking some data fields do not apply to the establishment under discussion and accordingly are blank. The set of nuclear facility profiles occupies four volumes; the profiles are ordered by country name, and then bymore » facility code. Each nuclear facility profile volume contains two complete indexes to the information. The first index aggregates the facilities alphabetically by country. It is further organized by category of facility, and then by the four-character facility code. It provides a quick summary of the nuclear energy capability or interest in each country and also an identifier, the facility code, which can be used to access the information contained in the profile.« less

  7. JAE: A Jupiter Atmospheric Entry Probe Heating Code

    NASA Technical Reports Server (NTRS)

    Wercinski, Paul F.; Tauber, Michael E.; Yang, Lily

    1997-01-01

    The strong gravitational attraction of Jupiter on probes approaching the planet results in very high atmospheric entry velocities. The values relative to the rotating atmosphere can vary from about 47 to 60 km/sec, depending on the latitude of the entry. Therefore, the peak heating rates and heat shield mass fractions exceed those for any other atmospheric entries. For example, the Galileo probe's heat shield mass fraction was 50%, of which 45% was devoted to the forebody. Although the Galileo probe's mission was very successful, many more scientific questions about the Jovian atmosphere remain to be answered and additional probe missions are being planned. Recent developments in microelectronics have raised the possibility of building smaller and less expensive probes than Galileo. Therefore, it was desirable to develop a code that could quickly compute the forebody entry heating environments when performing parametric probe sizing studies. The Jupiter Atmospheric Entry (JAE) code was developed to meet this requirement. The body geometry consists of a blunt-nosed conical shape of arbitrary nose and base radius and cone angles up to about 65 deg at zero angle of attack.

  8. Evaluation of an urban vegetative canopy scheme and impact on plume dispersion

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nelson, Matthew A; Williams, Michael D; Zajic, Dragan

    2009-01-01

    The Quick Urban and Industrial Complex (QUIC) atmospheric dispersion modeling system attempts to fill an important gap between the fast, but nonbuilding-aware Gaussian plume models and the building-aware but slow computational fluid dynamics (CFD) models. While Gaussian models have the ability to give answers quickly to emergency responders, they are unlikely to be able to adequately account for the effects of the building-induced complex flow patterns on the near-source dispersion of contaminants. QUIC uses a diagnostic massconsistent empirical wind model called QUIC-URB that is based on the methodology of Rockle (1990), (see also Kaplan and Dinar 1996). In this approach,more » the recirculation zones that form around and between buildings are inserted into the flow using empirical parameterizations and then the wind field is forced to be mass consistent. Although not as accurate as CFD codes, this approach is several orders of magnitude faster and accounts for the bulk effects of buildings.« less

  9. Horizontal lifelines - review of regulations and simple design method considering anchorage rigidity.

    PubMed

    Galy, Bertrand; Lan, André

    2018-03-01

    Among the many occupational risks construction workers encounter every day falling from a height is the most dangerous. The objective of this article is to propose a simple analytical design method for horizontal lifelines (HLLs) that considers anchorage flexibility. The article presents a short review of the standards and regulations/acts/codes concerning HLLs in Canada the USA and Europe. A static analytical approach is proposed considering anchorage flexibility. The analytical results are compared with a series of 42 dynamic fall tests and a SAP2000 numerical model. The experimental results show that the analytical method is a little conservative and overestimates the line tension in most cases with a maximum of 17%. The static SAP2000 results show a maximum 2.1% difference with the analytical method. The analytical method is accurate enough to safely design HLLs and quick design abaci are provided to allow the engineer to make quick on-site verification if needed.

  10. Identification of hemoglobin variants by top-down mass spectrometry using selected diagnostic product ions.

    PubMed

    Coelho Graça, Didia; Hartmer, Ralf; Jabs, Wolfgang; Beris, Photis; Clerici, Lorella; Stoermer, Carsten; Samii, Kaveh; Hochstrasser, Denis; Tsybin, Yury O; Scherl, Alexander; Lescuyer, Pierre

    2015-04-01

    Hemoglobin disorder diagnosis is a complex procedure combining several analytical steps. Due to the lack of specificity of the currently used protein analysis methods, the identification of uncommon hemoglobin variants (proteoforms) can become a hard task to accomplish. The aim of this work was to develop a mass spectrometry-based approach to quickly identify mutated protein sequences within globin chain variants. To reach this goal, a top-down electron transfer dissociation mass spectrometry method was developed for hemoglobin β chain analysis. A diagnostic product ion list was established with a color code strategy allowing to quickly and specifically localize a mutation in the hemoglobin β chain sequence. The method was applied to the analysis of rare hemoglobin β chain variants and an (A)γ-β fusion protein. The results showed that the developed data analysis process allows fast and reliable interpretation of top-down electron transfer dissociation mass spectra by nonexpert users in the clinical area.

  11. Transcriptator: An Automated Computational Pipeline to Annotate Assembled Reads and Identify Non Coding RNA.

    PubMed

    Tripathi, Kumar Parijat; Evangelista, Daniela; Zuccaro, Antonio; Guarracino, Mario Rosario

    2015-01-01

    RNA-seq is a new tool to measure RNA transcript counts, using high-throughput sequencing at an extraordinary accuracy. It provides quantitative means to explore the transcriptome of an organism of interest. However, interpreting this extremely large data into biological knowledge is a problem, and biologist-friendly tools are lacking. In our lab, we developed Transcriptator, a web application based on a computational Python pipeline with a user-friendly Java interface. This pipeline uses the web services available for BLAST (Basis Local Search Alignment Tool), QuickGO and DAVID (Database for Annotation, Visualization and Integrated Discovery) tools. It offers a report on statistical analysis of functional and Gene Ontology (GO) annotation's enrichment. It helps users to identify enriched biological themes, particularly GO terms, pathways, domains, gene/proteins features and protein-protein interactions related informations. It clusters the transcripts based on functional annotations and generates a tabular report for functional and gene ontology annotations for each submitted transcript to the web server. The implementation of QuickGo web-services in our pipeline enable the users to carry out GO-Slim analysis, whereas the integration of PORTRAIT (Prediction of transcriptomic non coding RNA (ncRNA) by ab initio methods) helps to identify the non coding RNAs and their regulatory role in transcriptome. In summary, Transcriptator is a useful software for both NGS and array data. It helps the users to characterize the de-novo assembled reads, obtained from NGS experiments for non-referenced organisms, while it also performs the functional enrichment analysis of differentially expressed transcripts/genes for both RNA-seq and micro-array experiments. It generates easy to read tables and interactive charts for better understanding of the data. The pipeline is modular in nature, and provides an opportunity to add new plugins in the future. Web application is freely available at: http://www-labgtp.na.icar.cnr.it/Transcriptator.

  12. Evaluation of the annual Canadian biodosimetry network intercomparisons

    PubMed Central

    Wilkins, Ruth C.; Beaton-Green, Lindsay A.; Lachapelle, Sylvie; Kutzner, Barbara C.; Ferrarotto, Catherine; Chauhan, Vinita; Marro, Leonora; Livingston, Gordon K.; Boulay Greene, Hillary; Flegal, Farrah N.

    2015-01-01

    Abstract Purpose: To evaluate the importance of annual intercomparisons for maintaining the capacity and capabilities of a well-established biodosimetry network in conjunction with assessing efficient and effective analysis methods for emergency response. Materials and methods: Annual intercomparisons were conducted between laboratories in the Canadian National Biological Dosimetry Response Plan. Intercomparisons were performed over a six-year period and comprised of the shipment of 10–12 irradiated, blinded blood samples for analysis by each of the participating laboratories. Dose estimates were determined by each laboratory using the dicentric chromosome assay (conventional and QuickScan scoring) and where possible the cytokinesis block micronucleus (CBMN) assay. Dose estimates were returned to the lead laboratory for evaluation and comparison. Results: Individual laboratories performed comparably from year to year with only slight fluctuations in performance. Dose estimates using the dicentric chromosome assay were accurate about 80% of the time and the QuickScan method for scoring the dicentric chromosome assay was proven to reduce the time of analysis without having a significant effect on the dose estimates. Although analysis with the CBMN assay was comparable to QuickScan scoring with respect to speed, the accuracy of the dose estimates was greatly reduced. Conclusions: Annual intercomparisons are necessary to maintain a network of laboratories for emergency response biodosimetry as they evoke confidence in their capabilities. PMID:25670072

  13. 77 FR 3241 - Notice of Proposed Information Collection Requests

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-23

    ... particular content of the survey, describing the sample design, the timeline for the survey activities, and..., school districts, schools, postsecondary institutions, and libraries. Surveys of teachers, students... Education Statistics Quick Response Information System (QRIS) consists of the Fast Response Survey System...

  14. Temporal Code-Driven Stimulation: Definition and Application to Electric Fish Signaling

    PubMed Central

    Lareo, Angel; Forlim, Caroline G.; Pinto, Reynaldo D.; Varona, Pablo; Rodriguez, Francisco de Borja

    2016-01-01

    Closed-loop activity-dependent stimulation is a powerful methodology to assess information processing in biological systems. In this context, the development of novel protocols, their implementation in bioinformatics toolboxes and their application to different description levels open up a wide range of possibilities in the study of biological systems. We developed a methodology for studying biological signals representing them as temporal sequences of binary events. A specific sequence of these events (code) is chosen to deliver a predefined stimulation in a closed-loop manner. The response to this code-driven stimulation can be used to characterize the system. This methodology was implemented in a real time toolbox and tested in the context of electric fish signaling. We show that while there are codes that evoke a response that cannot be distinguished from a control recording without stimulation, other codes evoke a characteristic distinct response. We also compare the code-driven response to open-loop stimulation. The discussed experiments validate the proposed methodology and the software toolbox. PMID:27766078

  15. Temporal Code-Driven Stimulation: Definition and Application to Electric Fish Signaling.

    PubMed

    Lareo, Angel; Forlim, Caroline G; Pinto, Reynaldo D; Varona, Pablo; Rodriguez, Francisco de Borja

    2016-01-01

    Closed-loop activity-dependent stimulation is a powerful methodology to assess information processing in biological systems. In this context, the development of novel protocols, their implementation in bioinformatics toolboxes and their application to different description levels open up a wide range of possibilities in the study of biological systems. We developed a methodology for studying biological signals representing them as temporal sequences of binary events. A specific sequence of these events (code) is chosen to deliver a predefined stimulation in a closed-loop manner. The response to this code-driven stimulation can be used to characterize the system. This methodology was implemented in a real time toolbox and tested in the context of electric fish signaling. We show that while there are codes that evoke a response that cannot be distinguished from a control recording without stimulation, other codes evoke a characteristic distinct response. We also compare the code-driven response to open-loop stimulation. The discussed experiments validate the proposed methodology and the software toolbox.

  16. QuickSmart: a basic academic skills intervention for middle school students with learning difficulties.

    PubMed

    Graham, Lorraine; Bellert, Anne; Thomas, Jenny; Pegg, John

    2007-01-01

    QuickSmart is a basic academic skills intervention designed for persistently low-achieving students in the middle years of schooling that aims to improve the automaticity of basic skills to improve higher-order processes, such as problem solving and comprehension, as measured on standardized tests. The QuickSmart instructional program consists of three structured, teacher- or teacher aide-directed, 30-minute, small-group lessons each week for approximately 26 weeks. In this study, 42 middle school students experiencing learning difficulties (LD) completed the QuickSmart reading program, and a further 42 students with LD took part in the QuickSmart mathematics program. To investigate the effects of the intervention, comparisons were made between the reading and mathematics progress of the intervention group and a group of 10 high-achieving and 10 average-achieving peers. The results indicated that although the standardized reading comprehension and mathematics scores of QuickSmart students remained below those of comparison students, they improved significantly from pretest to posttest. In contrast, the standardized scores of comparison students were not significantly different from pretest to posttest. On measures of response speed and accuracy gathered using the Cognitive Aptitude Assessment System (CAAS), QuickSmart students were able to narrow the gap between their performance and that of their high- and average-achieving peers. Implications are drawn regarding the importance of interventions that emphasize the automaticity of basic academic skills for students with learning difficulties.

  17. Combating QR-Code-Based Compromised Accounts in Mobile Social Networks.

    PubMed

    Guo, Dong; Cao, Jian; Wang, Xiaoqi; Fu, Qiang; Li, Qiang

    2016-09-20

    Cyber Physical Social Sensing makes mobile social networks (MSNs) popular with users. However, such attacks are rampant as malicious URLs are spread covertly through quick response (QR) codes to control compromised accounts in MSNs to propagate malicious messages. Currently, there are generally two types of methods to identify compromised accounts in MSNs: one type is to analyze the potential threats on wireless access points and the potential threats on handheld devices' operation systems so as to stop compromised accounts from spreading malicious messages; the other type is to apply the method of detecting compromised accounts in online social networks to MSNs. The above types of methods above focus neither on the problems of MSNs themselves nor on the interaction of sensors' messages, which leads to the restrictiveness of platforms and the simplification of methods. In order to stop the spreading of compromised accounts in MSNs effectively, the attacks have to be traced to their sources first. Through sensors, users exchange information in MSNs and acquire information by scanning QR codes. Therefore, analyzing the traces of sensor-related information helps to identify the compromised accounts in MSNs. This paper analyzes the diversity of information sending modes of compromised accounts and normal accounts, analyzes the regularity of GPS (Global Positioning System)-based location information, and introduces the concepts of entropy and conditional entropy so as to construct an entropy-based model based on machine learning strategies. To achieve the goal, about 500,000 accounts of Sina Weibo and about 100 million corresponding messages are collected. Through the validation, the accuracy rate of the model is proved to be as high as 87.6%, and the false positive rate is only 3.7%. Meanwhile, the comparative experiments of the feature sets prove that sensor-based location information can be applied to detect the compromised accounts in MSNs.

  18. Combating QR-Code-Based Compromised Accounts in Mobile Social Networks

    PubMed Central

    Guo, Dong; Cao, Jian; Wang, Xiaoqi; Fu, Qiang; Li, Qiang

    2016-01-01

    Cyber Physical Social Sensing makes mobile social networks (MSNs) popular with users. However, such attacks are rampant as malicious URLs are spread covertly through quick response (QR) codes to control compromised accounts in MSNs to propagate malicious messages. Currently, there are generally two types of methods to identify compromised accounts in MSNs: one type is to analyze the potential threats on wireless access points and the potential threats on handheld devices’ operation systems so as to stop compromised accounts from spreading malicious messages; the other type is to apply the method of detecting compromised accounts in online social networks to MSNs. The above types of methods above focus neither on the problems of MSNs themselves nor on the interaction of sensors’ messages, which leads to the restrictiveness of platforms and the simplification of methods. In order to stop the spreading of compromised accounts in MSNs effectively, the attacks have to be traced to their sources first. Through sensors, users exchange information in MSNs and acquire information by scanning QR codes. Therefore, analyzing the traces of sensor-related information helps to identify the compromised accounts in MSNs. This paper analyzes the diversity of information sending modes of compromised accounts and normal accounts, analyzes the regularity of GPS (Global Positioning System)-based location information, and introduces the concepts of entropy and conditional entropy so as to construct an entropy-based model based on machine learning strategies. To achieve the goal, about 500,000 accounts of Sina Weibo and about 100 million corresponding messages are collected. Through the validation, the accuracy rate of the model is proved to be as high as 87.6%, and the false positive rate is only 3.7%. Meanwhile, the comparative experiments of the feature sets prove that sensor-based location information can be applied to detect the compromised accounts in MSNs. PMID:27657071

  19. Hurricane Maria, 2017 Hydrographic Response for Puerto Rico and U.S. Virgin Islands by the NOAA Ship Thomas Jefferson

    NASA Astrophysics Data System (ADS)

    Gump, D.; Klemm, A.; van Westendorp, C.; Wood, D. A.; Doroba, J.

    2017-12-01

    After many coastal natural disasters, ports and harbors must be surveyed for navigation dangers, cleared, and opened as quickly as possible to facilitate recovery and reconstruction. The appropriate survey asset to use varies by location and condition. Routinely, hydrographic response to a natural disaster is conducted by survey teams with trailer-hitched vessels deployed quickly by land. This was the case for Hurricanes Harvey, Irma and Nate which struck mainland U.S. In the U.S. territories of Puerto Rico and the Virgin Islands post-Hurricane Maria, however, the devastation to the regional infrastructure resulted in a dearth of adequate accommodations, fuel, security and passable roads required to support a land-based response. On September 24th, 2017, NOAA Ship Thomas Jefferson (TJ), a 208-foot-long hydrographic survey vessel with a 38-person complement and two 28-foot-long survey launches, began an uninterrupted 20-day cruise to survey major ports around the islands. The ship's crew acquired high-resolution multibeam echo sounder (MBES) and concurrent object-detection side scan sonar (SSS) in and around 18 individual port facilities in 13 areas. The TJ is the appropriate platform for sustained remote response due to a self-contained infrastructure that supports deployment and recovery of survey launches, as well as 24/7 data processing facilities. The TJ crew produced digital terrain models and SSS mosaics, in addition to developing new reports on specific hazards overnight. These products quickly informed responders, stakeholders and responsible authorities about the efficacy of waterways.

  20. Coding of sounds in the auditory system and its relevance to signal processing and coding in cochlear implants.

    PubMed

    Moore, Brian C J

    2003-03-01

    To review how the properties of sounds are "coded" in the normal auditory system and to discuss the extent to which cochlear implants can and do represent these codes. Data are taken from published studies of the response of the cochlea and auditory nerve to simple and complex stimuli, in both the normal and the electrically stimulated ear. REVIEW CONTENT: The review describes: 1) the coding in the normal auditory system of overall level (which partly determines perceived loudness), spectral shape (which partly determines perceived timbre and the identity of speech sounds), periodicity (which partly determines pitch), and sound location; 2) the role of the active mechanism in the cochlea, and particularly the fast-acting compression associated with that mechanism; 3) the neural response patterns evoked by cochlear implants; and 4) how the response patterns evoked by implants differ from those observed in the normal auditory system in response to sound. A series of specific issues is then discussed, including: 1) how to compensate for the loss of cochlear compression; 2) the effective number of independent channels in a normal ear and in cochlear implantees; 3) the importance of independence of responses across neurons; 4) the stochastic nature of normal neural responses; 5) the possible role of across-channel coincidence detection; and 6) potential benefits of binaural implantation. Current cochlear implants do not adequately reproduce several aspects of the neural coding of sound in the normal auditory system. Improved electrode arrays and coding systems may lead to improved coding and, it is hoped, to better performance.

  1. Ethics in cyberspace- a philosophical approach

    NASA Astrophysics Data System (ADS)

    Vesna, J. Lourdu; Niveditha, D.

    2012-08-01

    Encouraging students to expand their search for knowledge in cyberspace has brought in new dimension, on the handling of the new technology by the students and brought to light whether or not our curriculum demand such leap development and furthermore will student use the Internet in more socially responsible way. Children begin to learn ethical values right from birth through?families?and?religious?institution.?They?are?considered?as?primary?sources?for?a?childís?ethical?education?while?schools have the responsibility to teach and reinforce some moral values. New technologies bring about the need to interpret old values in new ways, but also may call for the creation of new codes of conduct when new actions are made possible with the use of technology. Children can quickly identify whether the behavior is right or wrong in real world but when students use virtual world behavior may not be as easily judged to be right or wrong. This study attempts to show the prevailing misconception thecyber ethics among students. This paper examines basis ethical issues when students have had to make ethical decisions. The study will qualitatively explore the level of understanding of teachers concerns and role in bringing in an ethical behavior on students on the Internet. If a student encounters unsafe behavior on the Internet, the student will be able to behave and act appropriately.

  2. RAMICS: trainable, high-speed and biologically relevant alignment of high-throughput sequencing reads to coding DNA

    PubMed Central

    Wright, Imogen A.; Travers, Simon A.

    2014-01-01

    The challenge presented by high-throughput sequencing necessitates the development of novel tools for accurate alignment of reads to reference sequences. Current approaches focus on using heuristics to map reads quickly to large genomes, rather than generating highly accurate alignments in coding regions. Such approaches are, thus, unsuited for applications such as amplicon-based analysis and the realignment phase of exome sequencing and RNA-seq, where accurate and biologically relevant alignment of coding regions is critical. To facilitate such analyses, we have developed a novel tool, RAMICS, that is tailored to mapping large numbers of sequence reads to short lengths (<10 000 bp) of coding DNA. RAMICS utilizes profile hidden Markov models to discover the open reading frame of each sequence and aligns to the reference sequence in a biologically relevant manner, distinguishing between genuine codon-sized indels and frameshift mutations. This approach facilitates the generation of highly accurate alignments, accounting for the error biases of the sequencing machine used to generate reads, particularly at homopolymer regions. Performance improvements are gained through the use of graphics processing units, which increase the speed of mapping through parallelization. RAMICS substantially outperforms all other mapping approaches tested in terms of alignment quality while maintaining highly competitive speed performance. PMID:24861618

  3. Neural network for image compression

    NASA Astrophysics Data System (ADS)

    Panchanathan, Sethuraman; Yeap, Tet H.; Pilache, B.

    1992-09-01

    In this paper, we propose a new scheme for image compression using neural networks. Image data compression deals with minimization of the amount of data required to represent an image while maintaining an acceptable quality. Several image compression techniques have been developed in recent years. We note that the coding performance of these techniques may be improved by employing adaptivity. Over the last few years neural network has emerged as an effective tool for solving a wide range of problems involving adaptivity and learning. A multilayer feed-forward neural network trained using the backward error propagation algorithm is used in many applications. However, this model is not suitable for image compression because of its poor coding performance. Recently, a self-organizing feature map (SOFM) algorithm has been proposed which yields a good coding performance. However, this algorithm requires a long training time because the network starts with random initial weights. In this paper we have used the backward error propagation algorithm (BEP) to quickly obtain the initial weights which are then used to speedup the training time required by the SOFM algorithm. The proposed approach (BEP-SOFM) combines the advantages of the two techniques and, hence, achieves a good coding performance in a shorter training time. Our simulation results demonstrate the potential gains using the proposed technique.

  4. Status and Plans for the TRANSP Interpretive and Predictive Simulation Code

    NASA Astrophysics Data System (ADS)

    Kaye, Stanley; Andre, Robert; Marina, Gorelenkova; Yuan, Xingqui; Hawryluk, Richard; Jardin, Steven; Poli, Francesca

    2015-11-01

    TRANSP is an integrated interpretive and predictive transport analysis tool that incorporates state of the art heating/current drive sources and transport models. The treatments and transport solvers are becoming increasingly sophisticated and comprehensive. For instance, the ISOLVER component provides a free boundary equilibrium solution, while the PT_SOLVER transport solver is especially suited for stiff transport models such as TGLF. TRANSP also incorporates such source models as NUBEAM for neutral beam injection, GENRAY, TORAY, TORBEAM, TORIC and CQL3D for ICRH, LHCD, ECH and HHFW. The implementation of selected components makes efficient use of MPI for speed up of code calculations. TRANSP has a wide international user-base, and it is run on the FusionGrid to allow for timely support and quick turnaround by the PPPL Computational Plasma Physics Group. It is being used as a basis for both analysis and development of control algorithms and discharge operational scenarios, including simulation of ITER plasmas. This poster will describe present uses of the code worldwide, as well as plans for upgrading the physics modules and code framework. Progress on implementing TRANSP as a component in the ITER IMAS will also be described. This research was supported by the U.S. Department of Energy under contracts DE-AC02-09CH11466.

  5. Introduction to LINUX OS for new LINUX users - Basic Information Before Using The Kurucz Codes Under LINUX-.

    NASA Astrophysics Data System (ADS)

    Çay, M. Taşkin

    Recently the ATLAS suite (Kurucz) was ported to LINUX OS (Sbordone et al.). Those users of the suite unfamiliar with LINUX need to know some basic information to use these versions. This paper is a quick overview and introduction to LINUX OS. The reader is highly encouraged to own a book on LINUX OS for comprehensive use. Although the subjects and examples in this paper are for general use, they to help with the installation and running the ATLAS suite.

  6. FindGDPs: fast identification of primers for labeling microbial transcriptomes for DNA microarray analysis

    PubMed Central

    Blick, Robert J.; Revel, Andrew T.; Hansen, Eric J.

    2008-01-01

    Summary FindGDPs is a program that uses a greedy algorithm to quickly identify a set of genome-directed primers that specifically anneal to all of the open reading frames in a genome and that do not exhibit full-length complementarity to the members of another user-supplied set of nucleotide sequences. Availability The program code is distributed under the GNU General Public License at http://www8.utsouthwestern.edu/utsw/cda/dept131456/files/159331.html Contact eric.hansen@utsouthwestern.edu PMID:15593406

  7. Validated Metrics of Quick Flow Improve Assessments of Streamflow Generation Processes at the Long-Term Sleepers River Research Site

    NASA Astrophysics Data System (ADS)

    Sebestyen, S. D.; Shanley, J. B.

    2015-12-01

    There are multiple approaches to quantify quick flow components of streamflow. Physical hydrograph separations of quick flow using recession analysis (RA) are objective, reproducible, and easily calculated for long-duration streamflow records (years to decades). However, this approach has rarely been validated to have a physical basis for interpretation. In contrast, isotopic hydrograph separation (IHS) and end member mixing analysis using multiple solutes (EMMA) have been used to identify flow components and flowpath routing through catchment soils. Nonetheless, these two approaches are limited by data from limited and isolated periods (hours to weeks) during which more-intensive grab samples were analyzed. These limitations oftentimes make IHS and EMMA difficult to generalize beyond brief windows of time. At the Sleepers River Research Watershed (SRRW) in northern Vermont, USA, we have data from multiple snowmelt events over a two decade period and from multiple nested catchments to assess relationships among RA, IHS, and EMMA. Quick flow separations were highly correlated among the three techniques, which shows links among metrics of quick flow, water sources, and flow path routing in a small (41 ha), forested catchment (W-9) The similarity in responses validates a physical interpretation for a particular RA approach (the Ekhardt recursive RA filter). This validation provides a new tool to estimate new water inputs and flowpath routing for more and longer periods when chemical or isotopic tracers may not have been measured. At three other SRRW catchments, we found similar strong correlations among the three techniques. Consistent responses across four catchments provide evidence to support other research at the SRRW that shows that runoff generation mechanisms are similar despite differences in catchment sizes and land covers.

  8. Oscillations during observations: Dynamic oscillatory networks serving visuospatial attention.

    PubMed

    Wiesman, Alex I; Heinrichs-Graham, Elizabeth; Proskovec, Amy L; McDermott, Timothy J; Wilson, Tony W

    2017-10-01

    The dynamic allocation of neural resources to discrete features within a visual scene enables us to react quickly and accurately to salient environmental circumstances. A network of bilateral cortical regions is known to subserve such visuospatial attention functions; however the oscillatory and functional connectivity dynamics of information coding within this network are not fully understood. Particularly, the coding of information within prototypical attention-network hubs and the subsecond functional connections formed between these hubs have not been adequately characterized. Herein, we use the precise temporal resolution of magnetoencephalography (MEG) to define spectrally specific functional nodes and connections that underlie the deployment of attention in visual space. Twenty-three healthy young adults completed a visuospatial discrimination task designed to elicit multispectral activity in visual cortex during MEG, and the resulting data were preprocessed and reconstructed in the time-frequency domain. Oscillatory responses were projected to the cortical surface using a beamformer, and time series were extracted from peak voxels to examine their temporal evolution. Dynamic functional connectivity was then computed between nodes within each frequency band of interest. We find that visual attention network nodes are defined functionally by oscillatory frequency, that the allocation of attention to the visual space dynamically modulates functional connectivity between these regions on a millisecond timescale, and that these modulations significantly correlate with performance on a spatial discrimination task. We conclude that functional hubs underlying visuospatial attention are segregated not only anatomically but also by oscillatory frequency, and importantly that these oscillatory signatures promote dynamic communication between these hubs. Hum Brain Mapp 38:5128-5140, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  9. Proprioceptive influence on the optokinetic nystagmus.

    PubMed

    Botti, F; Anastasopoulos, D; Kostadima, V; Bambagioni, D; Pettorossi, V E

    2001-01-01

    The influence of neck and leg proprioceptive inputs on optokinetic-induced quick phases was studied in humans. Ten subjects received unidirectional horizontal optokinetic stimulation (10-20%/s) during sinusoidal neck, leg and combined neck + leg proprioceptive stimulation. The optokinetic reflex was measured by electro-oculography. Neck stimulation induced a shift in the nystagmus beating field in the opposite direction to body movement (gain 0.3 0.4, phase 140-180 degrees). The beating field shift resulted totally from the amplitude and frequency modulation of optokinetic quick phases, as slow phases were not affected. Leg proprioceptive stimulation induced a similar effect, but the phase of the response lagged by approximately 90 degrees compared with that of neck response. With combined neck + leg stimulation, the amplitude of the effect was a sum of the separate effects, but the phase coincided with that of the leg response. This suggests that neck and leg proprioceptive signals do not add linearly and that the leg signal determines the time of the response.

  10. Implicit Coupling Approach for Simulation of Charring Carbon Ablators

    NASA Technical Reports Server (NTRS)

    Chen, Yih-Kanq; Gokcen, Tahir

    2013-01-01

    This study demonstrates that coupling of a material thermal response code and a flow solver with nonequilibrium gas/surface interaction for simulation of charring carbon ablators can be performed using an implicit approach. The material thermal response code used in this study is the three-dimensional version of Fully Implicit Ablation and Thermal response program, which predicts charring material thermal response and shape change on hypersonic space vehicles. The flow code solves the reacting Navier-Stokes equations using Data Parallel Line Relaxation method. Coupling between the material response and flow codes is performed by solving the surface mass balance in flow solver and the surface energy balance in material response code. Thus, the material surface recession is predicted in flow code, and the surface temperature and pyrolysis gas injection rate are computed in material response code. It is demonstrated that the time-lagged explicit approach is sufficient for simulations at low surface heating conditions, in which the surface ablation rate is not a strong function of the surface temperature. At elevated surface heating conditions, the implicit approach has to be taken, because the carbon ablation rate becomes a stiff function of the surface temperature, and thus the explicit approach appears to be inappropriate resulting in severe numerical oscillations of predicted surface temperature. Implicit coupling for simulation of arc-jet models is performed, and the predictions are compared with measured data. Implicit coupling for trajectory based simulation of Stardust fore-body heat shield is also conducted. The predicted stagnation point total recession is compared with that predicted using the chemical equilibrium surface assumption

  11. Extension of applicable neutron energy of DARWIN up to 1 GeV.

    PubMed

    Satoh, D; Sato, T; Endo, A; Matsufuji, N; Takada, M

    2007-01-01

    The radiation-dose monitor, DARWIN, needs a set of response functions of the liquid organic scintillator to assess a neutron dose. SCINFUL-QMD is a Monte Carlo based computer code to evaluate the response functions. In order to improve the accuracy of the code, a new light-output function based on the experimental data was developed for the production and transport of protons deuterons, tritons, (3)He nuclei and alpha particles, and incorporated into the code. The applicable energy of DARWIN was extended to 1 GeV using the response functions calculated by the modified SCINFUL-QMD code.

  12. The Modified Cognitive Constructions Coding System: Reliability and Validity Assessments

    ERIC Educational Resources Information Center

    Moran, Galia S.; Diamond, Gary M.

    2006-01-01

    The cognitive constructions coding system (CCCS) was designed for coding client's expressed problem constructions on four dimensions: intrapersonal-interpersonal, internal-external, responsible-not responsible, and linear-circular. This study introduces, and examines the reliability and validity of, a modified version of the CCCS--a version that…

  13. Estimating Discharge and Nonpoint Source Nitrate Loading to Streams From Three End-Member Pathways Using High-Frequency Water Quality Data

    NASA Astrophysics Data System (ADS)

    Miller, Matthew P.; Tesoriero, Anthony J.; Hood, Krista; Terziotti, Silvia; Wolock, David M.

    2017-12-01

    The myriad hydrologic and biogeochemical processes taking place in watersheds occurring across space and time are integrated and reflected in the quantity and quality of water in streams and rivers. Collection of high-frequency water quality data with sensors in surface waters provides new opportunities to disentangle these processes and quantify sources and transport of water and solutes in the coupled groundwater-surface water system. A new approach for separating the streamflow hydrograph into three components was developed and coupled with high-frequency nitrate data to estimate time-variable nitrate loads from chemically dilute quick flow, chemically concentrated quick flow, and slowflow groundwater end-member pathways for periods of up to 2 years in a groundwater-dominated and a quick-flow-dominated stream in central Wisconsin, using only streamflow and in-stream water quality data. The dilute and concentrated quick flow end-members were distinguished using high-frequency specific conductance data. Results indicate that dilute quick flow contributed less than 5% of the nitrate load at both sites, whereas 89 ± 8% of the nitrate load at the groundwater-dominated stream was from slowflow groundwater, and 84 ± 25% of the nitrate load at the quick-flow-dominated stream was from concentrated quick flow. Concentrated quick flow nitrate concentrations varied seasonally at both sites, with peak concentrations in the winter that were 2-3 times greater than minimum concentrations during the growing season. Application of this approach provides an opportunity to assess stream vulnerability to nonpoint source nitrate loading and expected stream responses to current or changing conditions and practices in watersheds.

  14. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Redi, M.H.; Mynick, H.E.; Suewattana, M.

    Hamiltonian coordinate, guiding-center code calculations of the confinement of suprathermal ions in quasi-axisymmetric stellarator (QAS) designs have been carried out to evaluate the attractiveness of compact configurations which are optimized for ballooning stability. A new stellarator particle-following code is used to predict ion loss rates and particle confinement for thermal and neutral beam ions in a small experiment with R = 145 cm, B = 1-2 T and for alpha particles in a reactor-size device. In contrast to tokamaks, it is found that high edge poloidal flux has limited value in improving ion confinement in QAS, since collisional pitch-angle scatteringmore » drives ions into ripple wells and stochastic field regions, where they are quickly lost. The necessity for reduced stellarator ripple fields is emphasized. The high neutral beam ion loss predicted for these configurations suggests that more interesting physics could be explored with an experiment of less constrained size and magnetic field geometry.« less

  15. Development of computer-assisted instruction application for statistical data analysis android platform as learning resource

    NASA Astrophysics Data System (ADS)

    Hendikawati, P.; Arifudin, R.; Zahid, M. Z.

    2018-03-01

    This study aims to design an android Statistics Data Analysis application that can be accessed through mobile devices to making it easier for users to access. The Statistics Data Analysis application includes various topics of basic statistical along with a parametric statistics data analysis application. The output of this application system is parametric statistics data analysis that can be used for students, lecturers, and users who need the results of statistical calculations quickly and easily understood. Android application development is created using Java programming language. The server programming language uses PHP with the Code Igniter framework, and the database used MySQL. The system development methodology used is the Waterfall methodology with the stages of analysis, design, coding, testing, and implementation and system maintenance. This statistical data analysis application is expected to support statistical lecturing activities and make students easier to understand the statistical analysis of mobile devices.

  16. Sparse Coding and Counting for Robust Visual Tracking

    PubMed Central

    Liu, Risheng; Wang, Jing; Shang, Xiaoke; Wang, Yiyang; Su, Zhixun; Cai, Yu

    2016-01-01

    In this paper, we propose a novel sparse coding and counting method under Bayesian framework for visual tracking. In contrast to existing methods, the proposed method employs the combination of L0 and L1 norm to regularize the linear coefficients of incrementally updated linear basis. The sparsity constraint enables the tracker to effectively handle difficult challenges, such as occlusion or image corruption. To achieve real-time processing, we propose a fast and efficient numerical algorithm for solving the proposed model. Although it is an NP-hard problem, the proposed accelerated proximal gradient (APG) approach is guaranteed to converge to a solution quickly. Besides, we provide a closed solution of combining L0 and L1 regularized representation to obtain better sparsity. Experimental results on challenging video sequences demonstrate that the proposed method achieves state-of-the-art results both in accuracy and speed. PMID:27992474

  17. The development and evaluation of a new coding system for medical records.

    PubMed

    Papazissis, Elias

    2014-01-01

    The present study aims to develop a simple, reliable and easy tool enabling clinicians to codify the major part of individualized medical details (patient history and findings of physical examination) quickly and easily in routine medical practice, by entering data to a purpose-built software application, using structure data elements and detailed medical illustrations. We studied medical records of 9,320 patients and we extracted individualized medical details. We recorded the majority of symptoms and the majority of findings of physical examination into the system, which was named IMPACT® (Intelligent Medical Patient Record and Coding Tool). Subsequently the system was evaluated by clinicians, based on the examination of 1206 patients. The evaluation results showed that IMPACT® is an efficient tool, easy to use even under time-pressing conditions. IMPACT® seems to be a promising tool for illustration-guided, structured data entry of medical narrative, in electronic patient records.

  18. De Novo ORFs in Drosophila Are Important to Organismal Fitness and Evolved Rapidly from Previously Non-coding Sequences

    PubMed Central

    Reinhardt, Josephine A.; Wanjiru, Betty M.; Brant, Alicia T.; Saelao, Perot; Begun, David J.; Jones, Corbin D.

    2013-01-01

    How non-coding DNA gives rise to new protein-coding genes (de novo genes) is not well understood. Recent work has revealed the origins and functions of a few de novo genes, but common principles governing the evolution or biological roles of these genes are unknown. To better define these principles, we performed a parallel analysis of the evolution and function of six putatively protein-coding de novo genes described in Drosophila melanogaster. Reconstruction of the transcriptional history of de novo genes shows that two de novo genes emerged from novel long non-coding RNAs that arose at least 5 MY prior to evolution of an open reading frame. In contrast, four other de novo genes evolved a translated open reading frame and transcription within the same evolutionary interval suggesting that nascent open reading frames (proto-ORFs), while not required, can contribute to the emergence of a new de novo gene. However, none of the genes arose from proto-ORFs that existed long before expression evolved. Sequence and structural evolution of de novo genes was rapid compared to nearby genes and the structural complexity of de novo genes steadily increases over evolutionary time. Despite the fact that these genes are transcribed at a higher level in males than females, and are most strongly expressed in testes, RNAi experiments show that most of these genes are essential in both sexes during metamorphosis. This lethality suggests that protein coding de novo genes in Drosophila quickly become functionally important. PMID:24146629

  19. Clinical indicators for routine use in the evaluation of early psychosis intervention: development, training support and inter-rater reliability.

    PubMed

    Catts, Stanley V; Frost, Aaron D J; O'Toole, Brian I; Carr, Vaughan J; Lewin, Terry; Neil, Amanda L; Harris, Meredith G; Evans, Russell W; Crissman, Belinda R; Eadie, Kathy

    2011-01-01

    Clinical practice improvement carried out in a quality assurance framework relies on routinely collected data using clinical indicators. Herein we describe the development, minimum training requirements, and inter-rater agreement of indicators that were used in an Australian multi-site evaluation of the effectiveness of early psychosis (EP) teams. Surveys of clinician opinion and face-to-face consensus-building meetings were used to select and conceptually define indicators. Operationalization of definitions was achieved by iterative refinement until clinicians could be quickly trained to code indicators reliably. Calculation of percentage agreement with expert consensus coding was based on ratings of paper-based clinical vignettes embedded in a 2-h clinician training package. Consensually agreed upon conceptual definitions for seven clinical indicators judged most relevant to evaluating EP teams were operationalized for ease-of-training. Brief training enabled typical clinicians to code indicators with acceptable percentage agreement (60% to 86%). For indicators of suicide risk, psychosocial function, and family functioning this level of agreement was only possible with less precise 'broad range' expert consensus scores. Estimated kappa values indicated fair to good inter-rater reliability (kappa > 0.65). Inspection of contingency tables (coding category by health service) and modal scores across services suggested consistent, unbiased coding across services. Clinicians are able to agree upon what information is essential to routinely evaluate clinical practice. Simple indicators of this information can be designed and coding rules can be reliably applied to written vignettes after brief training. The real world feasibility of the indicators remains to be tested in field trials.

  20. Efficient burst image compression using H.265/HEVC

    NASA Astrophysics Data System (ADS)

    Roodaki-Lavasani, Hoda; Lainema, Jani

    2014-02-01

    New imaging use cases are emerging as more powerful camera hardware is entering consumer markets. One family of such use cases is based on capturing multiple pictures instead of just one when taking a photograph. That kind of a camera operation allows e.g. selecting the most successful shot from a sequence of images, showing what happened right before or after the shot was taken or combining the shots by computational means to improve either visible characteristics of the picture (such as dynamic range or focus) or the artistic aspects of the photo (e.g. by superimposing pictures on top of each other). Considering that photographic images are typically of high resolution and quality and the fact that these kind of image bursts can consist of at least tens of individual pictures, an efficient compression algorithm is desired. However, traditional video coding approaches fail to provide the random access properties these use cases require to achieve near-instantaneous access to the pictures in the coded sequence. That feature is critical to allow users to browse the pictures in an arbitrary order or imaging algorithms to extract desired pictures from the sequence quickly. This paper proposes coding structures that provide such random access properties while achieving coding efficiency superior to existing image coders. The results indicate that using HEVC video codec with a single reference picture fixed for the whole sequence can achieve nearly as good compression as traditional IPPP coding structures. It is also shown that the selection of the reference frame can further improve the coding efficiency.

  1. SPIDERMAN: an open-source code to model phase curves and secondary eclipses

    NASA Astrophysics Data System (ADS)

    Louden, Tom; Kreidberg, Laura

    2018-06-01

    We present SPIDERMAN (Secondary eclipse and Phase curve Integrator for 2D tempERature MAppiNg), a fast code for calculating exoplanet phase curves and secondary eclipses with arbitrary surface brightness distributions in two dimensions. Using a geometrical algorithm, the code solves exactly the area of sections of the disc of the planet that are occulted by the star. The code is written in C with a user-friendly Python interface, and is optimized to run quickly, with no loss in numerical precision. Approximately 1000 models can be generated per second in typical use, making Markov Chain Monte Carlo analyses practicable. The modular nature of the code allows easy comparison of the effect of multiple different brightness distributions for the data set. As a test case, we apply the code to archival data on the phase curve of WASP-43b using a physically motivated analytical model for the two-dimensional brightness map. The model provides a good fit to the data; however, it overpredicts the temperature of the nightside. We speculate that this could be due to the presence of clouds on the nightside of the planet, or additional reflected light from the dayside. When testing a simple cloud model, we find that the best-fitting model has a geometric albedo of 0.32 ± 0.02 and does not require a hot nightside. We also test for variation of the map parameters as a function of wavelength and find no statistically significant correlations. SPIDERMAN is available for download at https://github.com/tomlouden/spiderman.

  2. Quick-release medical tape

    PubMed Central

    Laulicht, Bryan; Langer, Robert; Karp, Jeffrey M.

    2012-01-01

    Medical tape that provides secure fixation of life-sustaining and -monitoring devices with quick, easy, damage-free removal represents a longstanding unmet medical need in neonatal care. During removal of current medical tapes, crack propagation occurs at the adhesive–skin interface, which is also the interface responsible for device fixation. By designing quick-release medical tape to undergo crack propagation between the backing and adhesive layers, we decouple removal and device fixation, enabling dual functionality. We created an ordered adhesive/antiadhesive composite intermediary layer between the medical tape backing and adhesive for which we achieve tunable peel removal force, while maintaining high shear adhesion to secure medical devices. We elucidate the relationship between the spatial ordering of adhesive and antiadhesive regions to create a fully tunable system that achieves strong device fixation and quick, easy, damage-free device removal. We also described ways of neutralizing the residual adhesive on the skin and have observed that thick continuous films of adhesive are easier to remove than the thin islands associated with residual adhesive left by current medical tapes. PMID:23112196

  3. Are low and high number magnitudes processed differently while resolving the conflict evoked by the SNARC effect?

    PubMed

    Gut, Małgorzata; Szumska, Izabela; Wasilewska, Marzena; Jaśkowski, Piotr

    2012-07-01

    In the brain, numbers are thought to be represented in a spatially organised fashion on what is known as the Mental Number Line (MNL). The SNARC (Spatial-Numerical Association of Response Codes) effect refers to the faster responses to digits when the reaction side is congruent with the digit position on the MNL (e.g. a left-handed response to a small magnitude) and the slowing down of responses (inhibition) in the case of incongruity. We examined the electrophysiological correlates of conflict, which are linked to that of inhibition, to shed light on the relationship between the SNARC effect and executive attention. Event-related potentials (ERPs) were recorded from twenty-nine participants during a parity-judgment task. The participants responded more quickly on congruent than on incongruent trials. The congruency effect was reflected in early sensory (N1, N2) components above parieto-occipital and frontal regions, as well as in the later P3 component above centro-parietal areas. Moreover, both the N1 amplitude and N2 latency were greater with high than low magnitude digit targets. P3 amplitude modulation implies that the SNARC effect is the result of first evoking the parallel processing of digit magnitude categorisation (in the occipital and central areas) and numeric conflict detection (in the parieto-occipital and frontal areas) and secondly conflict monitoring and resolution localised in the centro-parietal and frontal sites. These results also suggest that the left hemisphere specialises in conflict processing of high magnitude digit targets, while the right hemisphere of low digit magnitudes. Copyright © 2012 Elsevier B.V. All rights reserved.

  4. Improving travel times for emergency response vehicles : traffic control strategies based on connected vehicles technologies.

    DOT National Transportation Integrated Search

    2014-09-01

    This research is focused on developing and evaluating new traffic control strategies to enable emergency response vehicles : (EVs) to travel in transportation networks as quickly as possible while the disruption to the rest of the traffic is kept to ...

  5. SequenceCEROSENE: a computational method and web server to visualize spatial residue neighborhoods at the sequence level.

    PubMed

    Heinke, Florian; Bittrich, Sebastian; Kaiser, Florian; Labudde, Dirk

    2016-01-01

    To understand the molecular function of biopolymers, studying their structural characteristics is of central importance. Graphics programs are often utilized to conceive these properties, but with the increasing number of available structures in databases or structure models produced by automated modeling frameworks this process requires assistance from tools that allow automated structure visualization. In this paper a web server and its underlying method for generating graphical sequence representations of molecular structures is presented. The method, called SequenceCEROSENE (color encoding of residues obtained by spatial neighborhood embedding), retrieves the sequence of each amino acid or nucleotide chain in a given structure and produces a color coding for each residue based on three-dimensional structure information. From this, color-highlighted sequences are obtained, where residue coloring represent three-dimensional residue locations in the structure. This color encoding thus provides a one-dimensional representation, from which spatial interactions, proximity and relations between residues or entire chains can be deduced quickly and solely from color similarity. Furthermore, additional heteroatoms and chemical compounds bound to the structure, like ligands or coenzymes, are processed and reported as well. To provide free access to SequenceCEROSENE, a web server has been implemented that allows generating color codings for structures deposited in the Protein Data Bank or structure models uploaded by the user. Besides retrieving visualizations in popular graphic formats, underlying raw data can be downloaded as well. In addition, the server provides user interactivity with generated visualizations and the three-dimensional structure in question. Color encoded sequences generated by SequenceCEROSENE can aid to quickly perceive the general characteristics of a structure of interest (or entire sets of complexes), thus supporting the researcher in the initial phase of structure-based studies. In this respect, the web server can be a valuable tool, as users are allowed to process multiple structures, quickly switch between results, and interact with generated visualizations in an intuitive manner. The SequenceCEROSENE web server is available at https://biosciences.hs-mittweida.de/seqcerosene.

  6. Controlling Energy Radiations of Electromagnetic Waves via Frequency Coding Metamaterials.

    PubMed

    Wu, Haotian; Liu, Shuo; Wan, Xiang; Zhang, Lei; Wang, Dan; Li, Lianlin; Cui, Tie Jun

    2017-09-01

    Metamaterials are artificial structures composed of subwavelength unit cells to control electromagnetic (EM) waves. The spatial coding representation of metamaterial has the ability to describe the material in a digital way. The spatial coding metamaterials are typically constructed by unit cells that have similar shapes with fixed functionality. Here, the concept of frequency coding metamaterial is proposed, which achieves different controls of EM energy radiations with a fixed spatial coding pattern when the frequency changes. In this case, not only different phase responses of the unit cells are considered, but also different phase sensitivities are also required. Due to different frequency sensitivities of unit cells, two units with the same phase response at the initial frequency may have different phase responses at higher frequency. To describe the frequency coding property of unit cell, digitalized frequency sensitivity is proposed, in which the units are encoded with digits "0" and "1" to represent the low and high phase sensitivities, respectively. By this merit, two degrees of freedom, spatial coding and frequency coding, are obtained to control the EM energy radiations by a new class of frequency-spatial coding metamaterials. The above concepts and physical phenomena are confirmed by numerical simulations and experiments.

  7. Automatic Coding of Short Text Responses via Clustering in Educational Assessment

    ERIC Educational Resources Information Center

    Zehner, Fabian; Sälzer, Christine; Goldhammer, Frank

    2016-01-01

    Automatic coding of short text responses opens new doors in assessment. We implemented and integrated baseline methods of natural language processing and statistical modelling by means of software components that are available under open licenses. The accuracy of automatic text coding is demonstrated by using data collected in the "Programme…

  8. Parallelisation study of a three-dimensional environmental flow model

    NASA Astrophysics Data System (ADS)

    O'Donncha, Fearghal; Ragnoli, Emanuele; Suits, Frank

    2014-03-01

    There are many simulation codes in the geosciences that are serial and cannot take advantage of the parallel computational resources commonly available today. One model important for our work in coastal ocean current modelling is EFDC, a Fortran 77 code configured for optimal deployment on vector computers. In order to take advantage of our cache-based, blade computing system we restructured EFDC from serial to parallel, thereby allowing us to run existing models more quickly, and to simulate larger and more detailed models that were previously impractical. Since the source code for EFDC is extensive and involves detailed computation, it is important to do such a port in a manner that limits changes to the files, while achieving the desired speedup. We describe a parallelisation strategy involving surgical changes to the source files to minimise error-prone alteration of the underlying computations, while allowing load-balanced domain decomposition for efficient execution on a commodity cluster. The use of conjugate gradient posed particular challenges due to implicit non-local communication posing a hindrance to standard domain partitioning schemes; a number of techniques are discussed to address this in a feasible, computationally efficient manner. The parallel implementation demonstrates good scalability in combination with a novel domain partitioning scheme that specifically handles mixed water/land regions commonly found in coastal simulations. The approach presented here represents a practical methodology to rejuvenate legacy code on a commodity blade cluster with reasonable effort; our solution has direct application to other similar codes in the geosciences.

  9. A numerical similarity approach for using retired Current Procedural Terminology (CPT) codes for electronic phenotyping in the Scalable Collaborative Infrastructure for a Learning Health System (SCILHS).

    PubMed

    Klann, Jeffrey G; Phillips, Lori C; Turchin, Alexander; Weiler, Sarah; Mandl, Kenneth D; Murphy, Shawn N

    2015-12-11

    Interoperable phenotyping algorithms, needed to identify patient cohorts meeting eligibility criteria for observational studies or clinical trials, require medical data in a consistent structured, coded format. Data heterogeneity limits such algorithms' applicability. Existing approaches are often: not widely interoperable; or, have low sensitivity due to reliance on the lowest common denominator (ICD-9 diagnoses). In the Scalable Collaborative Infrastructure for a Learning Healthcare System (SCILHS) we endeavor to use the widely-available Current Procedural Terminology (CPT) procedure codes with ICD-9. Unfortunately, CPT changes drastically year-to-year - codes are retired/replaced. Longitudinal analysis requires grouping retired and current codes. BioPortal provides a navigable CPT hierarchy, which we imported into the Informatics for Integrating Biology and the Bedside (i2b2) data warehouse and analytics platform. However, this hierarchy does not include retired codes. We compared BioPortal's 2014AA CPT hierarchy with Partners Healthcare's SCILHS datamart, comprising three-million patients' data over 15 years. 573 CPT codes were not present in 2014AA (6.5 million occurrences). No existing terminology provided hierarchical linkages for these missing codes, so we developed a method that automatically places missing codes in the most specific "grouper" category, using the numerical similarity of CPT codes. Two informaticians reviewed the results. We incorporated the final table into our i2b2 SCILHS/PCORnet ontology, deployed it at seven sites, and performed a gap analysis and an evaluation against several phenotyping algorithms. The reviewers found the method placed the code correctly with 97 % precision when considering only miscategorizations ("correctness precision") and 52 % precision using a gold-standard of optimal placement ("optimality precision"). High correctness precision meant that codes were placed in a reasonable hierarchal position that a reviewer can quickly validate. Lower optimality precision meant that codes were not often placed in the optimal hierarchical subfolder. The seven sites encountered few occurrences of codes outside our ontology, 93 % of which comprised just four codes. Our hierarchical approach correctly grouped retired and non-retired codes in most cases and extended the temporal reach of several important phenotyping algorithms. We developed a simple, easily-validated, automated method to place retired CPT codes into the BioPortal CPT hierarchy. This complements existing hierarchical terminologies, which do not include retired codes. The approach's utility is confirmed by the high correctness precision and successful grouping of retired with non-retired codes.

  10. Novel insights into the response of Atlantic salmon (Salmo salar) to Piscirickettsia salmonis: Interplay of coding genes and lncRNAs during bacterial infection.

    PubMed

    Valenzuela-Miranda, Diego; Gallardo-Escárate, Cristian

    2016-12-01

    Despite the high prevalence and impact to Chilean salmon aquaculture of the intracellular bacterium Piscirickettsia salmonis, the molecular underpinnings of host-pathogen interactions remain unclear. Herein, the interplay of coding and non-coding transcripts has been proposed as a key mechanism involved in immune response. Therefore, the aim of this study was to evidence how coding and non-coding transcripts are modulated during the infection process of Atlantic salmon with P. salmonis. For this, RNA-seq was conducted in brain, spleen, and head kidney samples, revealing different transcriptional profiles according to bacterial load. Additionally, while most of the regulated genes annotated for diverse biological processes during infection, a common response associated with clathrin-mediated endocytosis and iron homeostasis was present in all tissues. Interestingly, while endocytosis-promoting factors and clathrin inductions were upregulated, endocytic receptors were mainly downregulated. Furthermore, the regulation of genes related to iron homeostasis suggested an intracellular accumulation of iron, a process in which heme biosynthesis/degradation pathways might play an important role. Regarding the non-coding response, 918 putative long non-coding RNAs were identified, where 425 were newly characterized for S. salar. Finally, co-localization and co-expression analyses revealed a strong correlation between the modulations of long non-coding RNAs and genes associated with endocytosis and iron homeostasis. These results represent the first comprehensive study of putative interplaying mechanisms of coding and non-coding RNAs during bacterial infection in salmonids. Copyright © 2016 Elsevier Ltd. All rights reserved.

  11. INVESTIGATION OF OPEN-PATH FTIR FOR FAST DEPLOYMENT EMERGENCY RESPONSE TO CHEMICAL THREATS AND ACCIDENTS.

    EPA Science Inventory

    We have performed a series of experiments to determine the tradeoff in detection sensitivity for implementing design features for an Open-Path Fourier Transform Infrared (OP-FTIR) chemical analyzer that would be quick to deploy under emergency response conditions. The fast-deplo...

  12. uRespond: iPad as Interactive, Personal Response System

    ERIC Educational Resources Information Center

    Bryfczynski, Samuel P.; Brown, Rebecca; Hester, Josiah; Herrmann, Andrew; Koch, Danielle L.; Cooper, Melanie M.; Grove, Nathaniel P.

    2014-01-01

    Personal response systems are quickly becoming indispensable formative assessment tools in many college-level chemistry courses. With the use of such devices, students are provided with invaluable insights into the skills perceived by the instructor as important, while concurrently, the instructor can gather feedback as to how well students have…

  13. Improving travel times for emergency response vehicles : traffic control strategies based on connected vehicles technologies : final report.

    DOT National Transportation Integrated Search

    2014-08-31

    This research is focused on developing and evaluating new traffic control strategies to enable emergency response vehicles (EVs) to travel in transportation networks as quickly as possible while the disruption to the rest of the traffic is kept to a ...

  14. Test-Anchored Vibration Response Predictions for an Acoustically Energized Curved Orthogrid Panel with Mounted Components

    NASA Technical Reports Server (NTRS)

    Frady, Gregory P.; Duvall, Lowery D.; Fulcher, Clay W. G.; Laverde, Bruce T.; Hunt, Ronald A.

    2011-01-01

    A rich body of vibroacoustic test data was recently generated at Marshall Space Flight Center for a curved orthogrid panel typical of launch vehicle skin structures. Several test article configurations were produced by adding component equipment of differing weights to the flight-like vehicle panel. The test data were used to anchor computational predictions of a variety of spatially distributed responses including acceleration, strain and component interface force. Transfer functions relating the responses to the input pressure field were generated from finite element based modal solutions and test-derived damping estimates. A diffuse acoustic field model was employed to describe the assumed correlation of phased input sound pressures across the energized panel. This application demonstrates the ability to quickly and accurately predict a variety of responses to acoustically energized skin panels with mounted components. Favorable comparisons between the measured and predicted responses were established. The validated models were used to examine vibration response sensitivities to relevant modeling parameters such as pressure patch density, mesh density, weight of the mounted component and model form. Convergence metrics include spectral densities and cumulative root-mean squared (RMS) functions for acceleration, velocity, displacement, strain and interface force. Minimum frequencies for response convergence were established as well as recommendations for modeling techniques, particularly in the early stages of a component design when accurate structural vibration requirements are needed relatively quickly. The results were compared with long-established guidelines for modeling accuracy of component-loaded panels. A theoretical basis for the Response/Pressure Transfer Function (RPTF) approach provides insight into trends observed in the response predictions and confirmed in the test data. The software modules developed for the RPTF method can be easily adapted for quick replacement of the diffuse acoustic field with other pressure field models; for example a turbulent boundary layer (TBL) model suitable for vehicle ascent. Wind tunnel tests have been proposed to anchor the predictions and provide new insight into modeling approaches for this type of environment. Finally, component vibration environments for design were developed from the measured and predicted responses and compared with those derived from traditional techniques such as Barrett scaling methods for unloaded and component-loaded panels.

  15. Potential application of item-response theory to interpretation of medical codes in electronic patient records

    PubMed Central

    2011-01-01

    Background Electronic patient records are generally coded using extensive sets of codes but the significance of the utilisation of individual codes may be unclear. Item response theory (IRT) models are used to characterise the psychometric properties of items included in tests and questionnaires. This study asked whether the properties of medical codes in electronic patient records may be characterised through the application of item response theory models. Methods Data were provided by a cohort of 47,845 participants from 414 family practices in the UK General Practice Research Database (GPRD) with a first stroke between 1997 and 2006. Each eligible stroke code, out of a set of 202 OXMIS and Read codes, was coded as either recorded or not recorded for each participant. A two parameter IRT model was fitted using marginal maximum likelihood estimation. Estimated parameters from the model were considered to characterise each code with respect to the latent trait of stroke diagnosis. The location parameter is referred to as a calibration parameter, while the slope parameter is referred to as a discrimination parameter. Results There were 79,874 stroke code occurrences available for analysis. Utilisation of codes varied between family practices with intraclass correlation coefficients of up to 0.25 for the most frequently used codes. IRT analyses were restricted to 110 Read codes. Calibration and discrimination parameters were estimated for 77 (70%) codes that were endorsed for 1,942 stroke patients. Parameters were not estimated for the remaining more frequently used codes. Discrimination parameter values ranged from 0.67 to 2.78, while calibration parameters values ranged from 4.47 to 11.58. The two parameter model gave a better fit to the data than either the one- or three-parameter models. However, high chi-square values for about a fifth of the stroke codes were suggestive of poor item fit. Conclusion The application of item response theory models to coded electronic patient records might potentially contribute to identifying medical codes that offer poor discrimination or low calibration. This might indicate the need for improved coding sets or a requirement for improved clinical coding practice. However, in this study estimates were only obtained for a small proportion of participants and there was some evidence of poor model fit. There was also evidence of variation in the utilisation of codes between family practices raising the possibility that, in practice, properties of codes may vary for different coders. PMID:22176509

  16. Nonlinear optical cryptosystem based on joint Fresnel transform correlator under vector wave illumination

    NASA Astrophysics Data System (ADS)

    Xueju, Shen; Chao, Lin; Xiao, Zou; Jianjun, Cai

    2015-05-01

    We present a nonlinear optical cryptosystem with multi-dimensional keys including phase, polarization and diffraction distance. To make full use of the degrees of freedom that optical processing offers, an elaborately designed vector wave with both a space-variant phase and locally linear polarization is generated with a common-path interferometer for illumination. The joint transform correlator in the Fresnel domain, implemented with a double optical wedge, is utilized as the encryption framework which provides an additional key known as the Fresnel diffraction distance. Two nonlinear operations imposed on the recorded joint Fresnel power distribution (JFPD) by a charge coupled device (CCD) are adopted. The first one is the division of power distribution of the reference window random function which is previously proposed by researchers and can improve the quality of the decrypted image. The second one is the recording of a hybrid JFPD using a micro-polarizers array with orthogonal and random transmissive axes attached to the CCD. Then the hybrid JFPD is further scrambled by substituting random noise for partial power distribution. The two nonlinear operations break the linearity of this cryptosystem and provide ultra security. We verify our proposal using a quick response code for noise-free recovery.

  17. Detecting spatial defects in colored patterns using self-oscillating gels

    NASA Astrophysics Data System (ADS)

    Fang, Yan; Yashin, Victor V.; Dickerson, Samuel J.; Balazs, Anna C.

    2018-06-01

    With the growing demand for wearable computers, there is a need for material systems that can perform computational tasks without relying on external electrical power. Using theory and simulation, we design a material system that "computes" by integrating the inherent behavior of self-oscillating gels undergoing the Belousov-Zhabotinsky (BZ) reaction and piezoelectric (PZ) plates. These "BZ-PZ" units are connected electrically to form a coupled oscillator network, which displays specific modes of synchronization. We exploit this attribute in employing multiple BZ-PZ networks to perform pattern matching on complex multi-dimensional data, such as colored images. By decomposing a colored image into sets of binary vectors, we use each BZ-PZ network, or "channel," to store distinct information about the color and the shape of the image and perform the pattern matching operation. Our simulation results indicate that the multi-channel BZ-PZ device can detect subtle differences between the input and stored patterns, such as the color variation of one pixel or a small change in the shape of an object. To demonstrate a practical application, we utilize our system to process a colored Quick Response code and show its potential in cryptography and steganography.

  18. Development of a challenge-protective vaccine concept by modification of the viral RNA-dependent RNA polymerase of canine distemper virus.

    PubMed

    Silin, D; Lyubomska, O; Ludlow, M; Duprex, W P; Rima, B K

    2007-12-01

    We demonstrate that insertion of the open reading frame of enhanced green fluorescent protein (EGFP) into the coding sequence for the second hinge region of the viral L (large) protein (RNA-dependent RNA polymerase) attenuates a wild-type canine distemper virus. Moreover, we show that single intranasal immunization with this recombinant virus provides significant protection against challenge with the virulent parental virus. Protection against wild-type challenge was gained either after recovery of cellular immunity postimmunization or after development of neutralizing antibodies. Insertion of EGFP seems to result in overattenuation of the virus, while our previous experiments demonstrated that the insertion of an epitope tag into a similar position did not affect L protein function. Thus, a desirable level of attenuation could be reached by manipulating the length of the insert (in the second hinge region of the L protein), providing additional tools for optimization of controlled attenuation. This strategy for controlled attenuation may be useful for a "quick response" in vaccine development against well-known and "new" viral infections and could be combined efficiently with other strategies of vaccine development and delivery systems.

  19. Stress sensitive electricity based on Ag/cellulose nanofiber aerogel for self-reporting.

    PubMed

    Yao, Qiufang; Fan, Bitao; Xiong, Ye; Wang, Chao; Wang, Hanwei; Jin, Chunde; Sun, Qingfeng

    2017-07-15

    A self-reporting aerogel toward stress sensitive slectricity (SSE) was presented using an interconnected 3D fibrous network of Ag nanoparticles/cellulose nanofiber aerogel (Ag/CNF), which was prepared via combined routes of silver mirror reaction and ultrasonication. Sphere-like Ag nanoparticles (AgNPs) with mean diameter of 74nm were tightly anchored in the cellulose nanofiber through by the coherent interfaces as the conductive materials. The as-prepared Ag/CNF as a self-reporting material for SSE not only possessed quick response and sensitivity, but also be easily recovered after 100th compressive cycles without plastic deformation or degradation in compressive strength. Consequently, Ag/CNF could play a viable role in self-reporting materials as a quick electric-stress responsive sensor. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. Knowing where is different from knowing what: Distinct response time profiles and accuracy effects for target location, orientation, and color probability.

    PubMed

    Jabar, Syaheed B; Filipowicz, Alex; Anderson, Britt

    2017-11-01

    When a location is cued, targets appearing at that location are detected more quickly. When a target feature is cued, targets bearing that feature are detected more quickly. These attentional cueing effects are only superficially similar. More detailed analyses find distinct temporal and accuracy profiles for the two different types of cues. This pattern parallels work with probability manipulations, where both feature and spatial probability are known to affect detection accuracy and reaction times. However, little has been done by way of comparing these effects. Are probability manipulations on space and features distinct? In a series of five experiments, we systematically varied spatial probability and feature probability along two dimensions (orientation or color). In addition, we decomposed response times into initiation and movement components. Targets appearing at the probable location were reported more quickly and more accurately regardless of whether the report was based on orientation or color. On the other hand, when either color probability or orientation probability was manipulated, response time and accuracy improvements were specific for that probable feature dimension. Decomposition of the response time benefits demonstrated that spatial probability only affected initiation times, whereas manipulations of feature probability affected both initiation and movement times. As detection was made more difficult, the two effects further diverged, with spatial probability disproportionally affecting initiation times and feature probability disproportionately affecting accuracy. In conclusion, all manipulations of probability, whether spatial or featural, affect detection. However, only feature probability affects perceptual precision, and precision effects are specific to the probable attribute.

  1. Controlling Energy Radiations of Electromagnetic Waves via Frequency Coding Metamaterials

    PubMed Central

    Wu, Haotian; Liu, Shuo; Wan, Xiang; Zhang, Lei; Wang, Dan; Li, Lianlin

    2017-01-01

    Metamaterials are artificial structures composed of subwavelength unit cells to control electromagnetic (EM) waves. The spatial coding representation of metamaterial has the ability to describe the material in a digital way. The spatial coding metamaterials are typically constructed by unit cells that have similar shapes with fixed functionality. Here, the concept of frequency coding metamaterial is proposed, which achieves different controls of EM energy radiations with a fixed spatial coding pattern when the frequency changes. In this case, not only different phase responses of the unit cells are considered, but also different phase sensitivities are also required. Due to different frequency sensitivities of unit cells, two units with the same phase response at the initial frequency may have different phase responses at higher frequency. To describe the frequency coding property of unit cell, digitalized frequency sensitivity is proposed, in which the units are encoded with digits “0” and “1” to represent the low and high phase sensitivities, respectively. By this merit, two degrees of freedom, spatial coding and frequency coding, are obtained to control the EM energy radiations by a new class of frequency‐spatial coding metamaterials. The above concepts and physical phenomena are confirmed by numerical simulations and experiments. PMID:28932671

  2. Quickly updatable hologram images with high performance photorefractive polymer composites

    NASA Astrophysics Data System (ADS)

    Tsutsumi, Naoto; Kinashi, Kenji; Nonomura, Asato; Sakai, Wataru

    2012-02-01

    We present here quickly updatable hologram images using high performance photorefractive (PR) polymer composite based on poly(N-vinyl carbazole) (PVCz). PVCz is one of the pioneer materials for photoconductive polymer. PVCz/7- DCST/CzEPA/TNF (44/35/20/1 by wt) gives high diffraction efficiency of 68 % at E = 45 V/μm with fast response speed. Response speed of optical diffraction is the key parameter for real-time 3D holographic display. Key parameter for obtaining quickly updatable hologram images is to control the glass transition temperature lower enough to enhance chromophore orientation. Object image of the reflected coin surface recorded with reference beam at 532 nm (green beam) in the PR polymer composite is simultaneously reconstructed using a red probe beam at 642 nm. Instead of using coin object, object image produced by a computer was displayed on a spatial light modulator (SLM) is used as an object for hologram. Reflected object beam from a SLM interfered with reference beam on PR polymer composite to record a hologram and simultaneously reconstructed by a red probe beam. Movie produced in a computer was recorded as a realtime hologram in the PR polymer composite and simultaneously clearly reconstructed with a video rate.

  3. In vivo induction of interferon gamma expression in grey horses with metastatic melanoma resulting from direct injection of plasmid DNA coding for equine interleukin 12.

    PubMed

    Müller, J-M V; Wissemann, J; Meli, M L; Dasen, G; Lutz, H; Heinzerling, L; Feige, K

    2011-11-01

    Whole blood pharmacokinetics of intratumourally injected naked plasmid DNA coding for equine Interleukin 12 (IL-12) was assessed as a means of in vivo gene transfer in the treatment of melanoma in grey horses. The expression of induced interferon gamma (IFN-g) was evaluated in order to determine the pharmacodynamic properties of in vivo gene transduction. Seven grey horses bearing melanoma were injected intratumourally with 250 µg naked plasmid DNA coding for IL-12. Peripheral blood and biopsies from the injection site were taken at 13 time points until day 14 post injection (p.i.). Samples were analysed using quantitative real-time PCR. Plasmid DNA was quantified in blood samples and mRNA expression for IFN-g in tissue samples. Plasmid DNA showed fast elimination kinetics with more than 99 % of the plasmid disappearing within 36 hours. IFN-g expression increased quickly after IL-12 plasmid injection, but varied between individual horses. Intratumoural injection of plasmid DNA is a feasible method for inducing transgene expression in vivo. Biological activity of the transgene IL-12 was confirmed by measuring expression of IFN-g.

  4. Base heating methodology improvements, volume 1

    NASA Technical Reports Server (NTRS)

    Bender, Robert L.; Reardon, John E.; Somers, Richard E.; Fulton, Michael S.; Smith, Sheldon D.; Pergament, Harold

    1992-01-01

    This document is the final report for NASA MSFC Contract NAS8-38141. The contracted effort had the broad objective of improving the launch vehicles ascent base heating methodology to improve and simplify the determination of that environment for Advanced Launch System (ALS) concepts. It was pursued as an Advanced Development Plan (ADP) for the Joint DoD/NASA ALS program office with project management assigned to NASA/MSFC. The original study was to be completed in 26 months beginning Sep. 1989. Because of several program changes and emphasis on evolving launch vehicle concepts, the period of performance was extended to the current completion date of Nov. 1992. A computer code incorporating the methodology improvements into a quick prediction tool was developed and is operational for basic configuration and propulsion concepts. The code and its users guide are also provided as part of the contract documentation. Background information describing the specific objectives, limitations, and goals of the contract is summarized. A brief chronology of the ALS/NLS program history is also presented to provide the reader with an overview of the many variables influencing the development of the code over the past three years.

  5. A network coding based routing protocol for underwater sensor networks.

    PubMed

    Wu, Huayang; Chen, Min; Guan, Xin

    2012-01-01

    Due to the particularities of the underwater environment, some negative factors will seriously interfere with data transmission rates, reliability of data communication, communication range, and network throughput and energy consumption of underwater sensor networks (UWSNs). Thus, full consideration of node energy savings, while maintaining a quick, correct and effective data transmission, extending the network life cycle are essential when routing protocols for underwater sensor networks are studied. In this paper, we have proposed a novel routing algorithm for UWSNs. To increase energy consumption efficiency and extend network lifetime, we propose a time-slot based routing algorithm (TSR).We designed a probability balanced mechanism and applied it to TSR. The theory of network coding is introduced to TSBR to meet the requirement of further reducing node energy consumption and extending network lifetime. Hence, time-slot based balanced network coding (TSBNC) comes into being. We evaluated the proposed time-slot based balancing routing algorithm and compared it with other classical underwater routing protocols. The simulation results show that the proposed protocol can reduce the probability of node conflicts, shorten the process of routing construction, balance energy consumption of each node and effectively prolong the network lifetime.

  6. Rational's experience using Ada for very large systems

    NASA Technical Reports Server (NTRS)

    Archer, James E., Jr.; Devlin, Michael T.

    1986-01-01

    The experience using the Rational Environment has confirmed the advantages forseen when the project was started. Interactive syntatic and semantic information makes a tremendous difference in the ease of constructing programs and making changes to them. The ability to follow semantic references makes it easier to understand exisiting programs and the impact of changes. The integrated debugger makes it much easier to find bugs and test fixes quickly. Taken together, these facilites have helped greatly in reducing the impact of ongoing maintenance of the ability to produce a new code. Similar improvements are anticipated as the same level of integration and interactivity are achieved for configuration management and version control. The environment has also proven useful in introducing personnel to the project and existing personnel to new parts of the system. Personnel benefit from the assistance with syntax and semantics; everyone benefits from the ability to traverse and understand the structure of unfamiliar software. It is often possible for someone completely unfamiliar with a body of code to use these facilities, to understand it well enough to successfully with a body of code to use these facilities to understand it well enough to successfully diagnose and fix bugs in a matter of minutes.

  7. A Network Coding Based Routing Protocol for Underwater Sensor Networks

    PubMed Central

    Wu, Huayang; Chen, Min; Guan, Xin

    2012-01-01

    Due to the particularities of the underwater environment, some negative factors will seriously interfere with data transmission rates, reliability of data communication, communication range, and network throughput and energy consumption of underwater sensor networks (UWSNs). Thus, full consideration of node energy savings, while maintaining a quick, correct and effective data transmission, extending the network life cycle are essential when routing protocols for underwater sensor networks are studied. In this paper, we have proposed a novel routing algorithm for UWSNs. To increase energy consumption efficiency and extend network lifetime, we propose a time-slot based routing algorithm (TSR).We designed a probability balanced mechanism and applied it to TSR. The theory of network coding is introduced to TSBR to meet the requirement of further reducing node energy consumption and extending network lifetime. Hence, time-slot based balanced network coding (TSBNC) comes into being. We evaluated the proposed time-slot based balancing routing algorithm and compared it with other classical underwater routing protocols. The simulation results show that the proposed protocol can reduce the probability of node conflicts, shorten the process of routing construction, balance energy consumption of each node and effectively prolong the network lifetime. PMID:22666045

  8. Report on Automated Semantic Analysis of Scientific and Engineering Codes

    NASA Technical Reports Server (NTRS)

    Stewart. Maark E. M.; Follen, Greg (Technical Monitor)

    2001-01-01

    The loss of the Mars Climate Orbiter due to a software error reveals what insiders know: software development is difficult and risky because, in part, current practices do not readily handle the complex details of software. Yet, for scientific software development the MCO mishap represents the tip of the iceberg; few errors are so public, and many errors are avoided with a combination of expertise, care, and testing during development and modification. Further, this effort consumes valuable time and resources even when hardware costs and execution time continually decrease. Software development could use better tools! This lack of tools has motivated the semantic analysis work explained in this report. However, this work has a distinguishing emphasis; the tool focuses on automated recognition of the fundamental mathematical and physical meaning of scientific code. Further, its comprehension is measured by quantitatively evaluating overall recognition with practical codes. This emphasis is necessary if software errors-like the MCO error-are to be quickly and inexpensively avoided in the future. This report evaluates the progress made with this problem. It presents recommendations, describes the approach, the tool's status, the challenges, related research, and a development strategy.

  9. Scheduling observational and physical practice: influence on the coding of simple motor sequences.

    PubMed

    Ellenbuerger, Thomas; Boutin, Arnaud; Blandin, Yannick; Shea, Charles H; Panzer, Stefan

    2012-01-01

    The main purpose of the present experiment was to determine the coordinate system used in the development of movement codes when observational and physical practice are scheduled across practice sessions. The task was to reproduce a 1,300-ms spatial-temporal pattern of elbow flexions and extensions. An intermanual transfer paradigm with a retention test and two effector (contralateral limb) transfer tests was used. The mirror effector transfer test required the same pattern of homologous muscle activation and sequence of limb joint angles as that performed or observed during practice, and the non-mirror effector transfer test required the same spatial pattern movements as that performed or observed. The test results following the first acquisition session replicated the findings of Gruetzmacher, Panzer, Blandin, and Shea (2011) . The results following the second acquisition session indicated a strong advantage for participants who received physical practice in both practice sessions or received observational practice followed by physical practice. This advantage was found on both the retention and the mirror transfer tests compared to the non-mirror transfer test. These results demonstrate that codes based in motor coordinates can be developed relatively quickly and effectively for a simple spatial-temporal movement sequence when participants are provided with physical practice or observation followed by physical practice, but physical practice followed by observational practice or observational practice alone limits the development of codes based in motor coordinates.

  10. RAMICS: trainable, high-speed and biologically relevant alignment of high-throughput sequencing reads to coding DNA.

    PubMed

    Wright, Imogen A; Travers, Simon A

    2014-07-01

    The challenge presented by high-throughput sequencing necessitates the development of novel tools for accurate alignment of reads to reference sequences. Current approaches focus on using heuristics to map reads quickly to large genomes, rather than generating highly accurate alignments in coding regions. Such approaches are, thus, unsuited for applications such as amplicon-based analysis and the realignment phase of exome sequencing and RNA-seq, where accurate and biologically relevant alignment of coding regions is critical. To facilitate such analyses, we have developed a novel tool, RAMICS, that is tailored to mapping large numbers of sequence reads to short lengths (<10 000 bp) of coding DNA. RAMICS utilizes profile hidden Markov models to discover the open reading frame of each sequence and aligns to the reference sequence in a biologically relevant manner, distinguishing between genuine codon-sized indels and frameshift mutations. This approach facilitates the generation of highly accurate alignments, accounting for the error biases of the sequencing machine used to generate reads, particularly at homopolymer regions. Performance improvements are gained through the use of graphics processing units, which increase the speed of mapping through parallelization. RAMICS substantially outperforms all other mapping approaches tested in terms of alignment quality while maintaining highly competitive speed performance. © The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research.

  11. Theoretical modeling of laser-induced plasmas using the ATOMIC code

    NASA Astrophysics Data System (ADS)

    Colgan, James; Johns, Heather; Kilcrease, David; Judge, Elizabeth; Barefield, James, II; Clegg, Samuel; Hartig, Kyle

    2014-10-01

    We report on efforts to model the emission spectra generated from laser-induced breakdown spectroscopy (LIBS). LIBS is a popular and powerful method of quickly and accurately characterizing unknown samples in a remote manner. In particular, LIBS is utilized by the ChemCam instrument on the Mars Science Laboratory. We model the LIBS plasma using the Los Alamos suite of atomic physics codes. Since LIBS plasmas generally have temperatures of somewhere between 3000 K and 12000 K, the emission spectra typically result from the neutral and singly ionized stages of the target atoms. We use the Los Alamos atomic structure and collision codes to generate sets of atomic data and use the plasma kinetics code ATOMIC to perform LTE or non-LTE calculations that generate level populations and an emission spectrum for the element of interest. In this presentation we compare the emission spectrum from ATOMIC with an Fe LIBS laboratory-generated plasma as well as spectra from the ChemCam instrument. We also discuss various physics aspects of the modeling of LIBS plasmas that are necessary for accurate characterization of the plasma, such as multi-element target composition effects, radiation transport effects, and accurate line shape treatments. The Los Alamos National Laboratory is operated by Los Alamos National Security, LLC for the National Nuclear Security Administration of the U.S. Department of Energy under Contract No. DE-AC5206NA25396.

  12. Generation of signature databases with fast codes

    NASA Astrophysics Data System (ADS)

    Bradford, Robert A.; Woodling, Arthur E.; Brazzell, James S.

    1990-09-01

    Using the FASTSIG signature code to generate optical signature databases for the Ground-based Surveillance and Traking System (GSTS) Program has improved the efficiency of the database generation process. The goal of the current GSTS database is to provide standardized, threat representative target signatures that can easily be used for acquisition and trk studies, discrimination algorithm development, and system simulations. Large databases, with as many as eight interpolalion parameters, are required to maintain the fidelity demands of discrimination and to generalize their application to other strateg systems. As the need increases for quick availability of long wave infrared (LWIR) target signatures for an evolving design4o-threat, FASTSIG has become a database generation alternative to using the industry standard OptiCal Signatures Code (OSC). FASTSIG, developed in 1985 to meet the unique strategic systems demands imposed by the discrimination function, has the significant advantage of being a faster running signature code than the OSC, typically requiring two percent of the cpu time. It uses analytical approximations to model axisymmetric targets, with the fidelity required for discrimination analysis. Access of the signature database is accomplished through use of the waveband integration and interpolation software, INTEG and SIGNAT. This paper gives details of this procedure as well as sample interpolated signatures and also covers sample verification by comparison to the OSC, in order to establish the fidelity of the FASTSIG generated database.

  13. Estimate of Space Radiation-Induced Cancer Risks for International Space Station Orbits

    NASA Technical Reports Server (NTRS)

    Wu, Honglu; Atwell, William; Cucinotta, Francis A.; Yang, Chui-hsu

    1996-01-01

    Excess cancer risks from exposures to space radiation are estimated for various orbits of the International Space Station (ISS). Organ exposures are computed with the transport codes, BRYNTRN and HZETRN, and the computerized anatomical male and computerized anatomical female models. Cancer risk coefficients in the National Council on Radiation Protection and Measurements report No. 98 are used to generate lifetime excess cancer incidence and cancer mortality after a one-month mission to ISS. The generated data are tabulated to serve as a quick reference for assessment of radiation risk to astronauts on ISS missions.

  14. Risk-Based Object Oriented Testing

    NASA Technical Reports Server (NTRS)

    Rosenberg, Linda H.; Stapko, Ruth; Gallo, Albert

    2000-01-01

    Software testing is a well-defined phase of the software development life cycle. Functional ("black box") testing and structural ("white box") testing are two methods of test case design commonly used by software developers. A lesser known testing method is risk-based testing, which takes into account the probability of failure of a portion of code as determined by its complexity. For object oriented programs, a methodology is proposed for identification of risk-prone classes. Risk-based testing is a highly effective testing technique that can be used to find and fix the most important problems as quickly as possible.

  15. Utility of a scanning densitometer in analyzing remotely sensed imagery

    NASA Technical Reports Server (NTRS)

    Dooley, J. T.

    1976-01-01

    The utility of a scanning densitometer for analyzing imagery in the NASA Lewis Research Center's regional remote sensing program was evaluated. Uses studied include: (1) quick-look screening of imagery by means of density slicing, magnification, color coding, and edge enhancement; (2) preliminary category classification of both low- and high-resolution data bases; and (3) quantitative measurement of the extent of features within selected areas. The densitometer was capable of providing fast, convenient, and relatively inexpensive preliminary analysis of aerial and satellite photography and scanner imagery involving land cover, water quality, strip mining, and energy conservation.

  16. Random search optimization based on genetic algorithm and discriminant function

    NASA Technical Reports Server (NTRS)

    Kiciman, M. O.; Akgul, M.; Erarslanoglu, G.

    1990-01-01

    The general problem of optimization with arbitrary merit and constraint functions, which could be convex, concave, monotonic, or non-monotonic, is treated using stochastic methods. To improve the efficiency of the random search methods, a genetic algorithm for the search phase and a discriminant function for the constraint-control phase were utilized. The validity of the technique is demonstrated by comparing the results to published test problem results. Numerical experimentation indicated that for cases where a quick near optimum solution is desired, a general, user-friendly optimization code can be developed without serious penalties in both total computer time and accuracy.

  17. genenames.org: the HGNC resources in 2011

    PubMed Central

    Seal, Ruth L.; Gordon, Susan M.; Lush, Michael J.; Wright, Mathew W.; Bruford, Elspeth A.

    2011-01-01

    The HUGO Gene Nomenclature Committee (HGNC) aims to assign a unique gene symbol and name to every human gene. The HGNC database currently contains almost 30 000 approved gene symbols, over 19 000 of which represent protein-coding genes. The public website, www.genenames.org, displays all approved nomenclature within Symbol Reports that contain data curated by HGNC editors and links to related genomic, phenotypic and proteomic information. Here we describe improvements to our resources, including a new Quick Gene Search, a new List Search, an integrated HGNC BioMart and a new Statistics and Downloads facility. PMID:20929869

  18. Don't forget about the Christchurch earthquake: Lessons learned from this disaster

    USGS Publications Warehouse

    Hamburger, Michael W.; Mooney, Walter D.

    2011-01-01

    In the aftermath of the devastating magnitude-9.0 earthquake and tsunami that struck the Tohoku region of Japan on March 11, attention quickly turned away from a much smaller, but also highly destructive earthquake that struck the city of Christchurch, New Zealand, just a few weeks earlier, on Feb. 22. Both events are stark reminders of human vulnerability to natural disasters and provide a harsh reality check: Even technologically advanced countries with modern building codes are not immune from earthquake disasters. The Christchurch earthquake carried an additional message: Urban devastation can be triggered even by moderate-sized earthquakes.

  19. Python-Assisted MODFLOW Application and Code Development

    NASA Astrophysics Data System (ADS)

    Langevin, C.

    2013-12-01

    The U.S. Geological Survey (USGS) has a long history of developing and maintaining free, open-source software for hydrological investigations. The MODFLOW program is one of the most popular hydrologic simulation programs released by the USGS, and it is considered to be the most widely used groundwater flow simulation code. MODFLOW was written using a modular design and a procedural FORTRAN style, which resulted in code that could be understood, modified, and enhanced by many hydrologists. The code is fast, and because it uses standard FORTRAN it can be run on most operating systems. Most MODFLOW users rely on proprietary graphical user interfaces for constructing models and viewing model results. Some recent efforts, however, have focused on construction of MODFLOW models using open-source Python scripts. Customizable Python packages, such as FloPy (https://code.google.com/p/flopy), can be used to generate input files, read simulation results, and visualize results in two and three dimensions. Automating this sequence of steps leads to models that can be reproduced directly from original data and rediscretized in space and time. Python is also being used in the development and testing of new MODFLOW functionality. New packages and numerical formulations can be quickly prototyped and tested first with Python programs before implementation in MODFLOW. This is made possible by the flexible object-oriented design capabilities available in Python, the ability to call FORTRAN code from Python, and the ease with which linear systems of equations can be solved using SciPy, for example. Once new features are added to MODFLOW, Python can then be used to automate comprehensive regression testing and ensure reliability and accuracy of new versions prior to release.

  20. Using Response Interruption and Redirection to Reduce Vocal Stereotypy

    ERIC Educational Resources Information Center

    Sheehey, Patricia H.; Wells, Jenny C.

    2018-01-01

    Response interruption and redirection, commonly referred to as RIR, is an evidence-based intervention that has been demonstrated to quickly reduce moderate to high levels of vocal stereotypy in children with autism spectrum disorder. The RIR intervention is a simple, three-step procedure that can be embedded in classroom instruction with minimal…

  1. Piloting a Polychotomous Partial-Credit Scoring Procedure in a Multiple-Choice Test

    ERIC Educational Resources Information Center

    Tsopanoglou, Antonios; Ypsilandis, George S.; Mouti, Anna

    2014-01-01

    Multiple-choice (MC) tests are frequently used to measure language competence because they are quick, economical and straightforward to score. While degrees of correctness have been investigated for partially correct responses in combined-response MC tests, degrees of incorrectness in distractors and the role they play in determining the…

  2. p3d--Python module for structural bioinformatics.

    PubMed

    Fufezan, Christian; Specht, Michael

    2009-08-21

    High-throughput bioinformatic analysis tools are needed to mine the large amount of structural data via knowledge based approaches. The development of such tools requires a robust interface to access the structural data in an easy way. For this the Python scripting language is the optimal choice since its philosophy is to write an understandable source code. p3d is an object oriented Python module that adds a simple yet powerful interface to the Python interpreter to process and analyse three dimensional protein structure files (PDB files). p3d's strength arises from the combination of a) very fast spatial access to the structural data due to the implementation of a binary space partitioning (BSP) tree, b) set theory and c) functions that allow to combine a and b and that use human readable language in the search queries rather than complex computer language. All these factors combined facilitate the rapid development of bioinformatic tools that can perform quick and complex analyses of protein structures. p3d is the perfect tool to quickly develop tools for structural bioinformatics using the Python scripting language.

  3. Testnodes: a Lightweight Node-Testing Infrastructure

    NASA Astrophysics Data System (ADS)

    Fay, R.; Bland, J.

    2014-06-01

    A key aspect of ensuring optimum cluster reliability and productivity lies in keeping worker nodes in a healthy state. Testnodes is a lightweight node testing solution developed at Liverpool. While Nagios has been used locally for general monitoring of hosts and services, Testnodes is optimised to answer one question: is there any reason this node should not be accepting jobs? This tight focus enables Testnodes to inspect nodes frequently with minimal impact and provide a comprehensive and easily extended check with each inspection. On the server side, Testnodes, implemented in python, interoperates with the Torque batch server to control the nodes production status. Testnodes remotely and in parallel executes client-side test scripts and processes the return codes and output, adjusting the node's online/offline status accordingly to preserve the integrity of the overall batch system. Testnodes reports via log, email and Nagios, allowing a quick overview of node status to be reviewed and specific node issues to be identified and resolved quickly. This presentation will cover testnodes design and implementation, together with the results of its use in production at Liverpool, and future development plans.

  4. Information sharing for traffic incident management.

    DOT National Transportation Integrated Search

    2009-01-01

    Traffic incident management focuses on developing procedures, implementing policies, and deploying technologies to more quickly identify incidents, improve response times, and more effectively and efficiently manage the incident scene. Because so man...

  5. "Diabetes has instant consequences…"

    MedlinePlus

    ... Javascript on. Feature: Diabetes Stories "Diabetes has instant consequences…" Past Issues / Fall 2009 Table of Contents Photo: ... to chuck it all. But Diabetes has instant consequences. You learn to be responsible pretty quickly, or ...

  6. 43 CFR 11.64 - Injury determination phase-testing and sampling methods.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    .... In developing these objectives, the availability of information from response actions relating to the...), test cases proving the code works, and any alteration of previously documented code made to adapt the... computer code (if any), test cases proving the code works, and any alteration of previously documented code...

  7. 43 CFR 11.64 - Injury determination phase-testing and sampling methods.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    .... In developing these objectives, the availability of information from response actions relating to the...), test cases proving the code works, and any alteration of previously documented code made to adapt the... computer code (if any), test cases proving the code works, and any alteration of previously documented code...

  8. 43 CFR 11.64 - Injury determination phase-testing and sampling methods.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    .... In developing these objectives, the availability of information from response actions relating to the...), test cases proving the code works, and any alteration of previously documented code made to adapt the... computer code (if any), test cases proving the code works, and any alteration of previously documented code...

  9. Auditory-neurophysiological responses to speech during early childhood: Effects of background noise

    PubMed Central

    White-Schwoch, Travis; Davies, Evan C.; Thompson, Elaine C.; Carr, Kali Woodruff; Nicol, Trent; Bradlow, Ann R.; Kraus, Nina

    2015-01-01

    Early childhood is a critical period of auditory learning, during which children are constantly mapping sounds to meaning. But learning rarely occurs under ideal listening conditions—children are forced to listen against a relentless din. This background noise degrades the neural coding of these critical sounds, in turn interfering with auditory learning. Despite the importance of robust and reliable auditory processing during early childhood, little is known about the neurophysiology underlying speech processing in children so young. To better understand the physiological constraints these adverse listening scenarios impose on speech sound coding during early childhood, auditory-neurophysiological responses were elicited to a consonant-vowel syllable in quiet and background noise in a cohort of typically-developing preschoolers (ages 3–5 yr). Overall, responses were degraded in noise: they were smaller, less stable across trials, slower, and there was poorer coding of spectral content and the temporal envelope. These effects were exacerbated in response to the consonant transition relative to the vowel, suggesting that the neural coding of spectrotemporally-dynamic speech features is more tenuous in noise than the coding of static features—even in children this young. Neural coding of speech temporal fine structure, however, was more resilient to the addition of background noise than coding of temporal envelope information. Taken together, these results demonstrate that noise places a neurophysiological constraint on speech processing during early childhood by causing a breakdown in neural processing of speech acoustics. These results may explain why some listeners have inordinate difficulties understanding speech in noise. Speech-elicited auditory-neurophysiological responses offer objective insight into listening skills during early childhood by reflecting the integrity of neural coding in quiet and noise; this paper documents typical response properties in this age group. These normative metrics may be useful clinically to evaluate auditory processing difficulties during early childhood. PMID:26113025

  10. New Tool Released for Engine-Airframe Blade-Out Structural Simulations

    NASA Technical Reports Server (NTRS)

    Lawrence, Charles

    2004-01-01

    Researchers at the NASA Glenn Research Center have enhanced a general-purpose finite element code, NASTRAN, for engine-airframe structural simulations during steady-state and transient operating conditions. For steady-state simulations, the code can predict critical operating speeds, natural modes of vibration, and forced response (e.g., cabin noise and component fatigue). The code can be used to perform static analysis to predict engine-airframe response and component stresses due to maneuver loads. For transient response, the simulation code can be used to predict response due to bladeoff events and subsequent engine shutdown and windmilling conditions. In addition, the code can be used as a pretest analysis tool to predict the results of the bladeout test required for FAA certification of new and derivative aircraft engines. Before the present analysis code was developed, all the major aircraft engine and airframe manufacturers in the United States and overseas were performing similar types of analyses to ensure the structural integrity of engine-airframe systems. Although there were many similarities among the analysis procedures, each manufacturer was developing and maintaining its own structural analysis capabilities independently. This situation led to high software development and maintenance costs, complications with manufacturers exchanging models and results, and limitations in predicting the structural response to the desired degree of accuracy. An industry-NASA team was formed to overcome these problems by developing a common analysis tool that would satisfy all the structural analysis needs of the industry and that would be available and supported by a commercial software vendor so that the team members would be relieved of maintenance and development responsibilities. Input from all the team members was used to ensure that everyone's requirements were satisfied and that the best technology was incorporated into the code. Furthermore, because the code would be distributed by a commercial software vendor, it would be more readily available to engine and airframe manufacturers, as well as to nonaircraft companies that did not previously have access to this capability.

  11. Does behaviour play a role in house fly resistance to imidacloprid-containing baits?

    PubMed

    Seraydar, K R; Kaufman, P E

    2015-03-01

    The objective of this research was to examine the role and type of behavioural mechanisms that function in house fly, Musca domestica L. (Diptera: Muscidae), resistance to an imidacloprid-containing commercial fly bait, QuickBayt(®) , using an insecticide-susceptible and an imidacloprid-resistant strain. Mortality and feeding behaviour were observed through choice bioassays of three post-imidacloprid selected house fly generations to determine whether flies would consume the bait in the presence of an alternative food source. Mortality rates in choice containers progressively decreased in post-selection flies as QuickBayt(®) no-choice selections proceeded. There were no differences between the proportions of flies observed contacting QuickBayt(®) and sugar, respectively, a finding that eliminates repellency as a mechanism of stimulus-dependent behavioural resistance. However, differences in QuickBayt(®) consumption and subsequent mortality between choice and no-choice containers provided strong support for the evolution of consumption irritancy- or taste aversion-related behavioural resistance. The results of this study support the responsible rotation of insecticide bait formulations for house fly control. © 2015 The Royal Entomological Society.

  12. Stochastic hyperfine interactions modeling library

    NASA Astrophysics Data System (ADS)

    Zacate, Matthew O.; Evenson, William E.

    2011-04-01

    The stochastic hyperfine interactions modeling library (SHIML) provides a set of routines to assist in the development and application of stochastic models of hyperfine interactions. The library provides routines written in the C programming language that (1) read a text description of a model for fluctuating hyperfine fields, (2) set up the Blume matrix, upon which the evolution operator of the system depends, and (3) find the eigenvalues and eigenvectors of the Blume matrix so that theoretical spectra of experimental techniques that measure hyperfine interactions can be calculated. The optimized vector and matrix operations of the BLAS and LAPACK libraries are utilized; however, there was a need to develop supplementary code to find an orthonormal set of (left and right) eigenvectors of complex, non-Hermitian matrices. In addition, example code is provided to illustrate the use of SHIML to generate perturbed angular correlation spectra for the special case of polycrystalline samples when anisotropy terms of higher order than A can be neglected. Program summaryProgram title: SHIML Catalogue identifier: AEIF_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEIF_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: GNU GPL 3 No. of lines in distributed program, including test data, etc.: 8224 No. of bytes in distributed program, including test data, etc.: 312 348 Distribution format: tar.gz Programming language: C Computer: Any Operating system: LINUX, OS X RAM: Varies Classification: 7.4 External routines: TAPP [1], BLAS [2], a C-interface to BLAS [3], and LAPACK [4] Nature of problem: In condensed matter systems, hyperfine methods such as nuclear magnetic resonance (NMR), Mössbauer effect (ME), muon spin rotation (μSR), and perturbed angular correlation spectroscopy (PAC) measure electronic and magnetic structure within Angstroms of nuclear probes through the hyperfine interaction. When interactions fluctuate at rates comparable to the time scale of a hyperfine method, there is a loss in signal coherence, and spectra are damped. The degree of damping can be used to determine fluctuation rates, provided that theoretical expressions for spectra can be derived for relevant physical models of the fluctuations. SHIML provides routines to help researchers quickly develop code to incorporate stochastic models of fluctuating hyperfine interactions in calculations of hyperfine spectra. Solution method: Calculations are based on the method for modeling stochastic hyperfine interactions for PAC by Winkler and Gerdau [5]. The method is extended to include other hyperfine methods following the work of Dattagupta [6]. The code provides routines for reading model information from text files, allowing researchers to develop new models quickly without the need to modify computer code for each new model to be considered. Restrictions: In the present version of the code, only methods that measure the hyperfine interaction on one probe spin state, such as PAC, μSR, and NMR, are supported. Running time: Varies

  13. Analytical modeling of intumescent coating thermal protection system in a JP-5 fuel fire environment

    NASA Technical Reports Server (NTRS)

    Clark, K. J.; Shimizu, A. B.; Suchsland, K. E.; Moyer, C. B.

    1974-01-01

    The thermochemical response of Coating 313 when exposed to a fuel fire environment was studied to provide a tool for predicting the reaction time. The existing Aerotherm Charring Material Thermal Response and Ablation (CMA) computer program was modified to treat swelling materials. The modified code is now designated Aerotherm Transient Response of Intumescing Materials (TRIM) code. In addition, thermophysical property data for Coating 313 were analyzed and reduced for use in the TRIM code. An input data sensitivity study was performed, and performance tests of Coating 313/steel substrate models were carried out. The end product is a reliable computational model, the TRIM code, which was thoroughly validated for Coating 313. The tasks reported include: generation of input data, development of swell model and implementation in TRIM code, sensitivity study, acquisition of experimental data, comparisons of predictions with data, and predictions with intermediate insulation.

  14. The specific purpose Monte Carlo code McENL for simulating the response of epithermal neutron lifetime well logging tools

    NASA Astrophysics Data System (ADS)

    Prettyman, T. H.; Gardner, R. P.; Verghese, K.

    1993-08-01

    A new specific purpose Monte Carlo code called McENL for modeling the time response of epithermal neutron lifetime tools is described. The weight windows technique, employing splitting and Russian roulette, is used with an automated importance function based on the solution of an adjoint diffusion model to improve the code efficiency. Complete composition and density correlated sampling is also included in the code, and can be used to study the effect on tool response of small variations in the formation, borehole, or logging tool composition and density. An illustration of the latter application is given for the density of a thermal neutron filter. McENL was benchmarked against test-pit data for the Mobil pulsed neutron porosity tool and was found to be very accurate. Results of the experimental validation and details of code performance are presented.

  15. Differential Expression Profile of lncRNAs from Primary Human Hepatocytes Following DEET and Fipronil Exposure

    PubMed Central

    Wallace, Andrew D.; Hodgson, Ernest; Roe, R. Michael

    2017-01-01

    While the synthesis and use of new chemical compounds is at an all-time high, the study of their potential impact on human health is quickly falling behind, and new methods are needed to assess their impact. We chose to examine the effects of two common environmental chemicals, the insect repellent N,N-diethyl-m-toluamide (DEET) and the insecticide fluocyanobenpyrazole (fipronil), on transcript levels of long non-protein coding RNAs (lncRNAs) in primary human hepatocytes using a global RNA-Seq approach. While lncRNAs are believed to play a critical role in numerous important biological processes, many still remain uncharacterized, and their functions and modes of action remain largely unclear, especially in relation to environmental chemicals. RNA-Seq showed that 100 µM DEET significantly increased transcript levels for 2 lncRNAs and lowered transcript levels for 18 lncRNAs, while fipronil at 10 µM increased transcript levels for 76 lncRNAs and decreased levels for 193 lncRNAs. A mixture of 100 µM DEET and 10 µM fipronil increased transcript levels for 75 lncRNAs and lowered transcript levels for 258 lncRNAs. This indicates a more-than-additive effect on lncRNA transcript expression when the two chemicals were presented in combination versus each chemical alone. Differentially expressed lncRNA genes were mapped to chromosomes, analyzed by proximity to neighboring protein-coding genes, and functionally characterized via gene ontology and molecular mapping algorithms. While further testing is required to assess the organismal impact of changes in transcript levels, this initial analysis links several of the dysregulated lncRNAs to processes and pathways critical to proper cellular function, such as the innate and adaptive immune response and the p53 signaling pathway. PMID:28991164

  16. An evolutionary framework for cultural change: Selectionism versus communal exchange

    NASA Astrophysics Data System (ADS)

    Gabora, Liane

    2013-06-01

    Dawkins' replicator-based conception of evolution has led to widespread mis-application of selectionism across the social sciences because it does not address the paradox that necessitated the theory of natural selection in the first place: how do organisms accumulate change when traits acquired over their lifetime are obliterated? This is addressed by von Neumann's concept of a self-replicating automaton (SRA). A SRA consists of a self-assembly code that is used in two distinct ways: (1) actively deciphered during development to construct a self-similar replicant, and (2) passively copied to the replicant to ensure that it can reproduce. Information that is acquired over a lifetime is not transmitted to offspring, whereas information that is inherited during copying is transmitted. In cultural evolution there is no mechanism for discarding acquired change. Acquired change can accumulate orders of magnitude faster than, and quickly overwhelm, inherited change due to differential replication of variants in response to selection. This prohibits a selectionist but not an evolutionary framework for culture and the creative processes that fuel it. The importance non-Darwinian processes in biological evolution is increasingly recognized. Recent work on the origin of life suggests that early life evolved through a non-Darwinian process referred to as communal exchange that does not involve a self-assembly code, and that natural selection emerged from this more haphazard, ancestral evolutionary process. It is proposed that communal exchange provides an evolutionary framework for culture that enables specification of cognitive features necessary for a (real or artificial) societies to evolve culture. This is supported by a computational model of cultural evolution and a conceptual network based program for documenting material cultural history, and it is consistent with high levels of human cooperation.

  17. Issues and approaches for electronic document approval and transmittal using digital signatures and text authentication: Prototype documentation

    NASA Astrophysics Data System (ADS)

    Boling, M. E.

    1989-09-01

    Prototypes were assembled pursuant to recommendations made in report K/DSRD-96, Issues and Approaches for Electronic Document Approval and Transmittal Using Digital Signatures and Text Authentication, and to examine and discover the possibilities for integrating available hardware and software to provide cost effective systems for digital signatures and text authentication. These prototypes show that on a LAN, a multitasking, windowed, mouse/keyboard menu-driven interface can be assembled to provide easy and quick access to bit-mapped images of documents, electronic forms and electronic mail messages with a means to sign, encrypt, deliver, receive or retrieve and authenticate text and signatures. In addition they show that some of this same software may be used in a classified environment using host to terminal transactions to accomplish these same operations. Finally, a prototype was developed demonstrating that binary files may be signed electronically and sent by point to point communication and over ARPANET to remote locations where the authenticity of the code and signature may be verified. Related studies on the subject of electronic signatures and text authentication using public key encryption were done within the Department of Energy. These studies include timing studies of public key encryption software and hardware and testing of experimental user-generated host resident software for public key encryption. This software used commercially available command-line source code. These studies are responsive to an initiative within the Office of the Secretary of Defense (OSD) for the protection of unclassified but sensitive data. It is notable that these related studies are all built around the same commercially available public key encryption products from the private sector and that the software selection was made independently by each study group.

  18. Emergency EDAPTS retainer support.

    DOT National Transportation Integrated Search

    2007-06-01

    The Efficient Deployment of Advanced Transportation Systems (EDAPTS) Smart Transit System Project : required various quick-response deployment support activities over the 26-month period from April 18, 2005 : to June 30, 2007. These activities requir...

  19. GBAS Ionospheric Anomaly Monitoring Based on a Two-Step Approach

    PubMed Central

    Zhao, Lin; Yang, Fuxin; Li, Liang; Ding, Jicheng; Zhao, Yuxin

    2016-01-01

    As one significant component of space environmental weather, the ionosphere has to be monitored using Global Positioning System (GPS) receivers for the Ground-Based Augmentation System (GBAS). This is because an ionospheric anomaly can pose a potential threat for GBAS to support safety-critical services. The traditional code-carrier divergence (CCD) methods, which have been widely used to detect the variants of the ionospheric gradient for GBAS, adopt a linear time-invariant low-pass filter to suppress the effect of high frequency noise on the detection of the ionospheric anomaly. However, there is a counterbalance between response time and estimation accuracy due to the fixed time constants. In order to release the limitation, a two-step approach (TSA) is proposed by integrating the cascaded linear time-invariant low-pass filters with the adaptive Kalman filter to detect the ionospheric gradient anomaly. The performance of the proposed method is tested by using simulated and real-world data, respectively. The simulation results show that the TSA can detect ionospheric gradient anomalies quickly, even when the noise is severer. Compared to the traditional CCD methods, the experiments from real-world GPS data indicate that the average estimation accuracy of the ionospheric gradient improves by more than 31.3%, and the average response time to the ionospheric gradient at a rate of 0.018 m/s improves by more than 59.3%, which demonstrates the ability of TSA to detect a small ionospheric gradient more rapidly. PMID:27240367

  20. System implications of the ambulance arrival-to-patient contact interval on response interval compliance.

    PubMed

    Campbell, J P; Gratton, M C; Salomone, J A; Lindholm, D J; Watson, W A

    1994-01-01

    In some emergency medical services (EMS) system designs, response time intervals are mandated with monetary penalties for noncompliance. These times are set with the goal of providing rapid, definitive patient care. The time interval of vehicle at scene-to-patient access (VSPA) has been measured, but its effect on response time interval compliance has not been determined. To determine the effect of the VSPA interval on the mandated code 1 (< 9 min) and code 2 (< 13 min) response time interval compliance in an urban, public-utility model system. A prospective, observational study used independent third-party riders to collect the VSPA interval for emergency life-threatening (code 1) and emergency nonlife-threatening (code 2) calls. The VSPA interval was added to the 9-1-1 call-to-dispatch and vehicle dispatch-to-scene intervals to determine the total time interval from call received until paramedic access to the patient (9-1-1 call-to-patient access). Compliance with the mandated response time intervals was determined using the traditional time intervals (9-1-1 call-to-scene) plus the VSPA time intervals (9-1-1 call-to-patient access). Chi-square was used to determine statistical significance. Of the 216 observed calls, 198 were matched to the traditional time intervals. Sixty-three were code 1, and 135 were code 2. Of the code 1 calls, 90.5% were compliant using 9-1-1 call-to-scene intervals dropping to 63.5% using 9-1-1 call-to-patient access intervals (p < 0.0005). Of the code 2 calls, 94.1% were compliant using 9-1-1 call-to-scene intervals. Compliance decreased to 83.7% using 9-1-1 call-to-patient access intervals (p = 0.012). The addition of the VSPA interval to the traditional time intervals impacts system response time compliance. Using 9-1-1 call-to-scene compliance as a basis for measuring system performance underestimates the time for the delivery of definitive care. This must be considered when response time interval compliances are defined.

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