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Sample records for radiat prot dosim

  1. Personnel Radiation Exposure Associated With X-Rays Emanating from U.S. Coast Guard LORAN High Voltage Vacuum Tube Transmitter Units

    DTIC Science & Technology

    2011-07-01

    thermoluminescent dosimetry measurements. Throughout this report, radiation units may be preceded by the prefix milli (m). This prefix divides a...RF) shielded ion chambers, radiographic film, and solid-state, integrating thermoluminescent and optically stimulated luminescent dosimeters...Blake, P.K. 1990. The U.S. Naval Dosimetry Center Thermoluminescent Dosimetry System. Radiat. Prot. Dosim., 30, 4, 231-236. EHO (USCG, Pacific Area

  2. Dosimétrie RPE alanine, étude de faisabilité et applications possibles

    NASA Astrophysics Data System (ADS)

    Kuntz, F.; Chabanais, B.; Karamanoukian, D.; Delpech, J. P.; Marchioni, E.

    1998-04-01

    Alanine ESR dosimetry presents a great interest for quality controls in radiotherapy. This new developped water equivalent alamine dosimeter allows a reproducible dose measurement, by a non-destructif readout technique in a large dose range. In this paper the stability of the dosimeter response has been shown but also its independance with the energy or the dose rate of the absorbed radiation. Through this different studies, one can broaden the application field of alanine/ESR dosimetry especially for in-vivo dosimetry. The results of the experiments and the intra operative treatment, indicate that this kind of dosimetry seems to be a promising technique for in-vivo quality controls in electron beam, γ ray or X-ray radiotherapy. Le dosimètre à l'alanine dépouillé par Résonance Paramagnétique Électronique (EPE), est pratiquement équivalent tissu et présente plusieurs caractéristiques intéressantes : la reproductibilité de sa mesure, son dépouillement non destructif, son faible fading, sa large gamme de mesure de dose (0,5 à 100 kGy). La réponse de ce dosimètre est, de plus, indépendante du débit de dose du rayonnement qu'il a absorbé ainsi que de son énergie. À travers plusieurs études, et un essai in-viro, nous ouvrons un important champ d'applications, faisant de la dosimétie RPE/Alanine un Outil prometteur pour le contrôle de la qualité des traitements radiothérapeutiques par faisceaux d'électrons, rayonnement X et photons γ.

  3. Apports de la spéciation biologique en dosimétrie interne

    NASA Astrophysics Data System (ADS)

    Paquet, F.; Ansoborlo, E.; Chazel, V.; Hengé-Napoli, M. H.; Houpert, P.

    1998-04-01

    Speciation studies consist in the determination of the molecular characteristics of the elements. The research currently carried out in that field is aimed at describing the intracellular deposit of the radionuclides and the complexation mechanisms which determine their behaviour. Such studies are developed in order to contribute towards the solution of two major problems in the field of internal dosimetry: the realistic assessment of the dose received by the target cells and the therapeutic removal of neptunium or uranium after internal contamination. The work presented thereafter resumes the main results obtained in that field. La spéciation est l',étude des caract,ristiques moléculaires des ,éléments radioactifs. Un des axes majeurs développé, dans ce domaine cherche à? décrire les mécanismes de complexation et de dépt des radionucléides dans les cellules. Ces ,études sont effectuées pour tenter d'élucider deux problèmes majeurs de la dosimétrie interne: l'estimation réaliste des doses reçues par les cellules cibles après contamination interne et amélioration des thérapeutiques proposées après incorporation accidentelle. Le présent rapport fait le point sur les derniers travaux réalisés, sur le Np et résume les principales avancées dans ce domaine.

  4. Track structure based modelling of light ion radiation effects on nuclear and mitochondrial DNA

    NASA Astrophysics Data System (ADS)

    Schmitt, Elke; Ottolenghi, Andrea; Dingfelder, Michael; Friedland, Werner; Kundrat, Pavel; Baiocco, Giorgio

    2016-07-01

    double-strand breaks", Mutat. Res. 793, 30-40 [4] Friedland, Schmitt, Kundrat (2015): "Modelling Proton bunches focussed to submicrometre scales: Low-LET Radiation damage in high-LET-like spatial structure", Radiat. Prot. Dosim. 166, 34-37 [5] Schmitt, Friedland, Kundrat, Dingfelder, Ottolenghi (2015): "Cross section scaling for track structure simulations of low-energy ions in liquid water", Radiat. Prot. Dosim. 166, 15-18} Supported by the European Atomic Energy Community's Seventh Framework Programme (FP7/2007-2011) under grant agreement no 249689 "DoReMi" and the German Federal Ministry on Education and Research (KVSF-Projekt "LET-Verbund").

  5. The Universal Protein Resource (UniProt)

    PubMed Central

    2008-01-01

    The Universal Protein Resource (UniProt) provides a stable, comprehensive, freely accessible, central resource on protein sequences and functional annotation. The UniProt Consortium is a collaboration between the European Bioinformatics Institute (EBI), the Protein Information Resource (PIR) and the Swiss Institute of Bioinformatics (SIB). The core activities include manual curation of protein sequences assisted by computational analysis, sequence archiving, development of a user-friendly UniProt website, and the provision of additional value-added information through cross-references to other databases. UniProt is comprised of four major components, each optimized for different uses: the UniProt Knowledgebase, the UniProt Reference Clusters, the UniProt Archive and the UniProt Metagenomic and Environmental Sequences database. UniProt is updated and distributed every three weeks, and can be accessed online for searches or download at http://www.uniprot.org. PMID:18045787

  6. Calcul par simulation des paramètres dosimétriques pour le noyau cellulaire après irradiation α in vitro

    NASA Astrophysics Data System (ADS)

    Le Foll, L.; Bailly, I.; Fritsch, P.

    1998-04-01

    Determination of absorbed dose in biological targets after high LET α particules irradiation needs heavy calculations. A softwave has been developed in order to allow everyone to calculate hit probability and absorbed dose. It is particularly adapted to the study of cell cultures irradiated with electrodeposited source or α-beam accelerator. It is based first, on a random generator of α-track homogeneously distributed in 4π, second, on the evaluation of energy loss in the different media along the track and then on a statistical analysis of the results. This method is accurate and low time consuming. The target is either modelised by an ellipsoid or represented by its 3D shape recorded using confocal microscopy. Des calculs dosimétriques complexes sont nécessaires pour l'évaluation des doses délivrées dans des cibles biologiques après irradiation par des particules α de haut TEL. Un logiciel a été développé pour rendre facilement accessible le calcul de la probabilité pour atteindre la cible et de la dose absorbée. il est particulièrement adapté à l'étude des cultures cellulaires irradiées par des sources électrodéposées de radionucléides ou des accélérateurs de particules. Il repose sur un générateur de traces aléatoires, sur une approximation de la perte d'énergie dans les différents milieux traversés et sur une exploitation statistique des résultats obtenus. Cette méthode s'avère précise et rapide. La cible est modélisée par un ellipsoïde ou représentée par son image 3D obtenue en microscopie confocale.

  7. UniProtKB/Swiss-Prot, the Manually Annotated Section of the UniProt KnowledgeBase: How to Use the Entry View.

    PubMed

    Boutet, Emmanuel; Lieberherr, Damien; Tognolli, Michael; Schneider, Michel; Bansal, Parit; Bridge, Alan J; Poux, Sylvain; Bougueleret, Lydie; Xenarios, Ioannis

    2016-01-01

    The Universal Protein Resource (UniProt, http://www.uniprot.org ) consortium is an initiative of the SIB Swiss Institute of Bioinformatics (SIB), the European Bioinformatics Institute (EBI) and the Protein Information Resource (PIR) to provide the scientific community with a central resource for protein sequences and functional information. The UniProt consortium maintains the UniProt KnowledgeBase (UniProtKB), updated every 4 weeks, and several supplementary databases including the UniProt Reference Clusters (UniRef) and the UniProt Archive (UniParc).The Swiss-Prot section of the UniProt KnowledgeBase (UniProtKB/Swiss-Prot) contains publicly available expertly manually annotated protein sequences obtained from a broad spectrum of organisms. Plant protein entries are produced in the frame of the Plant Proteome Annotation Program (PPAP), with an emphasis on characterized proteins of Arabidopsis thaliana and Oryza sativa. High level annotations provided by UniProtKB/Swiss-Prot are widely used to predict annotation of newly available proteins through automatic pipelines.The purpose of this chapter is to present a guided tour of a UniProtKB/Swiss-Prot entry. We will also present some of the tools and databases that are linked to each entry.

  8. The Universal Protein Resource (UniProt) 2009

    PubMed Central

    2009-01-01

    The mission of UniProt is to provide the scientific community with a comprehensive, high-quality and freely accessible resource of protein sequence and functional information that is essential for modern biological research. UniProt is produced by the UniProt Consortium which consists of groups from the European Bioinformatics Institute, the Protein Information Resource and the Swiss Institute of Bioinformatics. The core activities include manual curation of protein sequences assisted by computational analysis, sequence archiving, a user-friendly UniProt website and the provision of additional value-added information through cross-references to other databases. UniProt is comprised of four major components, each optimized for different uses: the UniProt Archive, the UniProt Knowledgebase, the UniProt Reference Clusters and the UniProt Metagenomic and Environmental Sequence Database. One of the key achievements of the UniProt consortium in 2008 is the completion of the first draft of the complete human proteome in UniProtKB/Swiss-Prot. This manually annotated representation of all currently known human protein-coding genes was made available in UniProt release 14.0 with 20 325 entries. UniProt is updated and distributed every three weeks and can be accessed online for searches or downloaded at www.uniprot.org. PMID:18836194

  9. Plant Protein Annotation in the UniProt Knowledgebase1

    PubMed Central

    Schneider, Michel; Bairoch, Amos; Wu, Cathy H.; Apweiler, Rolf

    2005-01-01

    The Swiss-Prot, TrEMBL, Protein Information Resource (PIR), and DNA Data Bank of Japan (DDBJ) protein database activities have united to form the Universal Protein Resource (UniProt) Consortium. UniProt presents three database layers: the UniProt Archive, the UniProt Knowledgebase (UniProtKB), and the UniProt Reference Clusters. The UniProtKB consists of two sections: UniProtKB/Swiss-Prot (fully manually curated entries) and UniProtKB/TrEMBL (automated annotation, classification and extensive cross-references). New releases are published fortnightly. A specific Plant Proteome Annotation Program (http://www.expasy.org/sprot/ppap/) was initiated to cope with the increasing amount of data produced by the complete sequencing of plant genomes. Through UniProt, our aim is to provide the scientific community with a single, centralized, authoritative resource for protein sequences and functional information that will allow the plant community to fully explore and utilize the wealth of information available for both plant and nonplant model organisms. PMID:15888679

  10. UniProt: the universal protein knowledgebase

    PubMed Central

    2017-01-01

    The UniProt knowledgebase is a large resource of protein sequences and associated detailed annotation. The database contains over 60 million sequences, of which over half a million sequences have been curated by experts who critically review experimental and predicted data for each protein. The remainder are automatically annotated based on rule systems that rely on the expert curated knowledge. Since our last update in 2014, we have more than doubled the number of reference proteomes to 5631, giving a greater coverage of taxonomic diversity. We implemented a pipeline to remove redundant highly similar proteomes that were causing excessive redundancy in UniProt. The initial run of this pipeline reduced the number of sequences in UniProt by 47 million. For our users interested in the accessory proteomes, we have made available sets of pan proteome sequences that cover the diversity of sequences for each species that is found in its strains and sub-strains. To help interpretation of genomic variants, we provide tracks of detailed protein information for the major genome browsers. We provide a SPARQL endpoint that allows complex queries of the more than 22 billion triples of data in UniProt (http://sparql.uniprot.org/). UniProt resources can be accessed via the website at http://www.uniprot.org/. PMID:27899622

  11. Radiation

    NASA Video Gallery

    Outside the protective cocoon of Earth's atmosphere, the universe is full of harmful radiation. Astronauts who live and work in space are exposed not only to ultraviolet rays but also to space radi...

  12. The UniProtKB guide to the human proteome

    PubMed Central

    Breuza, Lionel; Poux, Sylvain; Estreicher, Anne; Famiglietti, Maria Livia; Magrane, Michele; Tognolli, Michael; Bridge, Alan; Baratin, Delphine; Redaschi, Nicole

    2016-01-01

    Advances in high-throughput and advanced technologies allow researchers to routinely perform whole genome and proteome analysis. For this purpose, they need high-quality resources providing comprehensive gene and protein sets for their organisms of interest. Using the example of the human proteome, we will describe the content of a complete proteome in the UniProt Knowledgebase (UniProtKB). We will show how manual expert curation of UniProtKB/Swiss-Prot is complemented by expert-driven automatic annotation to build a comprehensive, high-quality and traceable resource. We will also illustrate how the complexity of the human proteome is captured and structured in UniProtKB. Database URL: www.uniprot.org PMID:26896845

  13. 48 CFR 1019.202-70 - The Treasury Mentor Protégé Program.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... equipment; (4) Property; (5) Temporary assignment of personnel to protégé for purpose of training; and (6... the evaluation period, to develop the technical and corporate administrative expertise of a protégé...

  14. 48 CFR 1819.7204 - Protégé selection.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... the NASA Program more than two times as a protégé. (e) Protégés will be required to submit a protégé... received during the two preceding fiscal years. (Show prime contracts and subcontracts separately per year... received during the two preceding fiscal years. (Show prime contracts and subcontracts separately per...

  15. 48 CFR 3052.219-71 - DHS mentor-protégé program.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...; and (3) Mentor-Protégé agreements, approved by the DHS OSDBU. (c) Mentor participation in the program... 48 Federal Acquisition Regulations System 7 2011-10-01 2011-10-01 false DHS mentor-protégÃ... CONTRACT CLAUSES Text of Provisions and Clauses 3052.219-71 DHS mentor-protégé program. As prescribed...

  16. 48 CFR 3052.219-71 - DHS mentor-protégé program.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...; and (3) Mentor-Protégé agreements, approved by the DHS OSDBU. (c) Mentor participation in the program... 48 Federal Acquisition Regulations System 7 2013-10-01 2012-10-01 true DHS mentor-protégÃ... CONTRACT CLAUSES Text of Provisions and Clauses 3052.219-71 DHS mentor-protégé program. As prescribed...

  17. 48 CFR 3052.219-71 - DHS mentor-protégé program.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...; and (3) Mentor-Protégé agreements, approved by the DHS OSDBU. (c) Mentor participation in the program... 48 Federal Acquisition Regulations System 7 2014-10-01 2014-10-01 false DHS mentor-protégÃ... CONTRACT CLAUSES Text of Provisions and Clauses 3052.219-71 DHS mentor-protégé program. As prescribed...

  18. 48 CFR 719.273-9 - Obligations under the Mentor-Protégé Program.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Mentor or Protégé may voluntarily withdraw from the Program. However, in no event shall such withdrawal...-Protégé Program impacted the Protégé'(s) ability to receive contract(s) and subcontract(s) from private... mutually agreed upon Program period, the conclusion of the contract, or the voluntary withdrawal by...

  19. Minimizing proteome redundancy in the UniProt Knowledgebase

    PubMed Central

    Bursteinas, Borisas; Britto, Ramona; Bely, Benoit; Auchincloss, Andrea; Rivoire, Catherine; Redaschi, Nicole; O'Donovan, Claire; Martin, Maria Jesus

    2016-01-01

    Advances in high-throughput sequencing have led to an unprecedented growth in genome sequences being submitted to biological databases. In particular, the sequencing of large numbers of nearly identical bacterial genomes during infection outbreaks and for other large-scale studies has resulted in a high level of redundancy in nucleotide databases and consequently in the UniProt Knowledgebase (UniProtKB). Redundancy negatively impacts on database searches by causing slower searches, an increase in statistical bias and cumbersome result analysis. The redundancy combined with the large data volume increases the computational costs for most reuses of UniProtKB data. All of this poses challenges for effective discovery in this wealth of data. With the continuing development of sequencing technologies, it is clear that finding ways to minimize redundancy is crucial to maintaining UniProt's essential contribution to data interpretation by our users. We have developed a methodology to identify and remove highly redundant proteomes from UniProtKB. The procedure identifies redundant proteomes by performing pairwise alignments of sets of sequences for pairs of proteomes and subsequently, applies graph theory to find dominating sets that provide a set of non-redundant proteomes with a minimal loss of information. This method was implemented for bacteria in mid-2015, resulting in a removal of 50 million proteins in UniProtKB. With every new release, this procedure is used to filter new incoming proteomes, resulting in a more scalable and scientifically valuable growth of UniProtKB. Database URL: http://www.uniprot.org/proteomes/ PMID:28025334

  20. A mentor-protégé program for new faculty, part I: stories of protégés.

    PubMed

    White, Anne; Brannan, Jane; Wilson, Carol B

    2010-11-01

    With the projected shortage of nursing faculty, formalized programs are needed to provide mentorship programs that will encourage and support faculty as they move from the role of novice to expert educator. The purpose of this qualitative study is to explore the experience of protégés participating in a mentorship program for novice faculty. An interpretive phenomenological research study was conducted to illuminate the meaning of the experiences of the protégés participating in the program. The study of the experience of protégés participating in a mentor-protégé program led to the emergence of three main themes: Creating a Meaningful Mentor-Protégé Relationship, Transitioning as a New Nurse Educator, and the Mentor-Protégé Program-Lessons Learned. Data from the study will provide insight into the meaning of receiving mentorship in the role of novice nurse educator.

  1. The Universal Protein Resource (UniProt): an expanding universe of protein information.

    PubMed

    Wu, Cathy H; Apweiler, Rolf; Bairoch, Amos; Natale, Darren A; Barker, Winona C; Boeckmann, Brigitte; Ferro, Serenella; Gasteiger, Elisabeth; Huang, Hongzhan; Lopez, Rodrigo; Magrane, Michele; Martin, Maria J; Mazumder, Raja; O'Donovan, Claire; Redaschi, Nicole; Suzek, Baris

    2006-01-01

    The Universal Protein Resource (UniProt) provides a central resource on protein sequences and functional annotation with three database components, each addressing a key need in protein bioinformatics. The UniProt Knowledgebase (UniProtKB), comprising the manually annotated UniProtKB/Swiss-Prot section and the automatically annotated UniProtKB/TrEMBL section, is the preeminent storehouse of protein annotation. The extensive cross-references, functional and feature annotations and literature-based evidence attribution enable scientists to analyse proteins and query across databases. The UniProt Reference Clusters (UniRef) speed similarity searches via sequence space compression by merging sequences that are 100% (UniRef100), 90% (UniRef90) or 50% (UniRef50) identical. Finally, the UniProt Archive (UniParc) stores all publicly available protein sequences, containing the history of sequence data with links to the source databases. UniProt databases continue to grow in size and in availability of information. Recent and upcoming changes to database contents, formats, controlled vocabularies and services are described. New download availability includes all major releases of UniProtKB, sequence collections by taxonomic division and complete proteomes. A bibliography mapping service has been added, and an ID mapping service will be available soon. UniProt databases can be accessed online at http://www.uniprot.org or downloaded at ftp://ftp.uniprot.org/pub/databases/.

  2. EST2Prot: Mapping EST sequences to proteins

    PubMed Central

    Shafer, Paul; Lin, David M; Yona, Golan

    2006-01-01

    Background EST libraries are used in various biological studies, from microarray experiments to proteomic and genetic screens. These libraries usually contain many uncharacterized ESTs that are typically ignored since they cannot be mapped to known genes. Consequently, new discoveries are possibly overlooked. Results We describe a system (EST2Prot) that uses multiple elements to map EST sequences to their corresponding protein products. EST2Prot uses UniGene clusters, substring analysis, information about protein coding regions in existing DNA sequences and protein database searches to detect protein products related to a query EST sequence. Gene Ontology terms, Swiss-Prot keywords, and protein similarity data are used to map the ESTs to functional descriptors. Conclusion EST2Prot extends and significantly enriches the popular UniGene mapping by utilizing multiple relations between known biological entities. It produces a mapping between ESTs and proteins in real-time through a simple web-interface. The system is part of the Biozon database and is accessible at . PMID:16515706

  3. 48 CFR 819.7107 - Selection of Protégé firms.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS VA Mentor-Protégé Program 819.7107 Selection of Protégé firms... select from a broad base of SDVOSB or VOSB firms whose core competencies support VA's mission; and choose SDVOSB and/or VOSB protégés in addition to firms with whom they have established business...

  4. 48 CFR 1852.219-77 - NASA Mentor-Protégé Program.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false NASA Mentor-ProtégÃ... and Clauses 1852.219-77 NASA Mentor-Protégé Program. As prescribed in 1819.7215, insert the following clause: NASA Mentor-Protégé Program (Month/Year) (a) Prime contractors are encouraged to participate...

  5. 48 CFR 1852.219-77 - NASA Mentor-Protégé Program.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false NASA Mentor-ProtégÃ... and Clauses 1852.219-77 NASA Mentor-Protégé Program. As prescribed in 1819.7215, insert the following clause: NASA Mentor-Protégé Program (Month/Year) (a) Prime contractors are encouraged to participate...

  6. 48 CFR 1852.219-77 - NASA Mentor-Protégé Program.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true NASA Mentor-ProtégÃ... and Clauses 1852.219-77 NASA Mentor-Protégé Program. As prescribed in 1819.7215, insert the following clause: NASA Mentor-Protégé Program (MAY 2009) (a) Prime contractors are encouraged to participate in...

  7. 48 CFR 1852.219-77 - NASA Mentor-Protégé Program.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false NASA Mentor-ProtégÃ... and Clauses 1852.219-77 NASA Mentor-Protégé Program. As prescribed in 1819.7215, insert the following clause: NASA Mentor-Protégé Program (Month/Year) (a) Prime contractors are encouraged to participate...

  8. 48 CFR 1852.219-77 - NASA Mentor-Protégé Program.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false NASA Mentor-ProtégÃ... and Clauses 1852.219-77 NASA Mentor-Protégé Program. As prescribed in 1819.7215, insert the following clause: NASA Mentor-Protégé Program (Month/Year) (a) Prime contractors are encouraged to participate...

  9. 48 CFR 619.202-70 - The Department of State Mentor-Protégé Program.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... of personnel to protégé for purpose of training; and, (6) Any other types of permissible, mutually... period, to develop the technical and corporate administrative expertise of a protégé as defined in...

  10. 48 CFR 619.202-70 - The Department of State Mentor-Protégé Program.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... of personnel to protégé for purpose of training; and, (6) Any other types of permissible, mutually... period, to develop the technical and corporate administrative expertise of a protégé as defined in...

  11. 48 CFR 619.202-70 - The Department of State Mentor-Protégé Program.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... of personnel to protégé for purpose of training; and, (6) Any other types of permissible, mutually... period, to develop the technical and corporate administrative expertise of a protégé as defined in...

  12. LassoProt: server to analyze biopolymers with lassos

    PubMed Central

    Dabrowski-Tumanski, Pawel; Niemyska, Wanda; Pasznik, Pawel; Sulkowska, Joanna I.

    2016-01-01

    The LassoProt server, http://lassoprot.cent.uw.edu.pl/, enables analysis of biopolymers with entangled configurations called lassos. The server offers various ways of visualizing lasso configurations, as well as their time trajectories, with all the results and plots downloadable. Broad spectrum of applications makes LassoProt a useful tool for biologists, biophysicists, chemists, polymer physicists and mathematicians. The server and our methods have been validated on the whole PDB, and the results constitute the database of proteins with complex lassos, supported with basic biological data. This database can serve as a source of information about protein geometry and entanglement-function correlations, as a reference set in protein modeling, and for many other purposes. PMID:27131383

  13. LassoProt: server to analyze biopolymers with lassos.

    PubMed

    Dabrowski-Tumanski, Pawel; Niemyska, Wanda; Pasznik, Pawel; Sulkowska, Joanna I

    2016-07-08

    The LassoProt server, http://lassoprot.cent.uw.edu.pl/, enables analysis of biopolymers with entangled configurations called lassos. The server offers various ways of visualizing lasso configurations, as well as their time trajectories, with all the results and plots downloadable. Broad spectrum of applications makes LassoProt a useful tool for biologists, biophysicists, chemists, polymer physicists and mathematicians. The server and our methods have been validated on the whole PDB, and the results constitute the database of proteins with complex lassos, supported with basic biological data. This database can serve as a source of information about protein geometry and entanglement-function correlations, as a reference set in protein modeling, and for many other purposes.

  14. 49 CFR Appendix D to Part 26 - Mentor-Protégé Program Guidelines

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 1 2012-10-01 2012-10-01 false Mentor-Protégé Program Guidelines D Appendix D... BUSINESS ENTERPRISES IN DEPARTMENT OF TRANSPORTATION FINANCIAL ASSISTANCE PROGRAMS Pt. 26, App. D Appendix D to Part 26—Mentor-Protégé Program Guidelines (A) The purpose of this program element is to...

  15. 49 CFR Appendix D to Part 26 - Mentor-Protégé Program Guidelines

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 1 2013-10-01 2013-10-01 false Mentor-Protégé Program Guidelines D Appendix D... BUSINESS ENTERPRISES IN DEPARTMENT OF TRANSPORTATION FINANCIAL ASSISTANCE PROGRAMS Pt. 26, App. D Appendix D to Part 26—Mentor-Protégé Program Guidelines (A) The purpose of this program element is to...

  16. 48 CFR 552.219-75 - GSA Mentor-Protégé Program.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... the GSA Office of Small Business Utilization (E), Washington, DC 20405, (202) 501-1021, for further... Mentor-ProtéGé Program (SEP 2009) (a) Prime contractors, including small businesses, are encouraged to... subcontracting plan, or that are eligible small businesses; (2) Protégés are subcontractors to the...

  17. 48 CFR 852.219-71 - VA mentor-protégé program.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...-Protégé Program (DEC 2009) (a) Large businesses are encouraged to participate in the VA Mentor-Protégé... small businesses and veteran-owned small businesses to enhance the small businesses' capabilities and..., which are service-disabled veteran-owned small business concerns or veteran-owned small...

  18. 48 CFR 519.7008 - Selection of protégé firms.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., women-owned small business concerns, veteran-owned small business concerns, service-disabled veteran... subcontractor or a newly selected subcontractor for the prime contractor's GSA contract. (b) Mentor firms may have more than one protégé. GSA reserves the right to limit the number of protégés participating...

  19. 48 CFR 652.219-72 - Department of State Mentor-Protégé Program.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 4 2014-10-01 2014-10-01 false Department of State Mentor....219-72 Department of State Mentor-Protégé Program. As prescribed in 619.202-70(o)(1), insert the following provision: Department of State Mentor-Protégé Program (APR 2004) (a) Large and small...

  20. 48 CFR 652.219-72 - Department of State Mentor-Protégé Program.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Department of State Mentor....219-72 Department of State Mentor-Protégé Program. As prescribed in 619.202-70(o)(1), insert the following provision: Department of State Mentor-Protégé Program (APR 2004) (a) Large and small...

  1. 48 CFR 652.219-72 - Department of State Mentor-Protégé Program.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Department of State Mentor....219-72 Department of State Mentor-Protégé Program. As prescribed in 619.202-70(o)(1), insert the following provision: Department of State Mentor-Protégé Program (APR 2004) (a) Large and small...

  2. 48 CFR 652.219-72 - Department of State Mentor-Protégé Program.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 4 2012-10-01 2012-10-01 false Department of State Mentor....219-72 Department of State Mentor-Protégé Program. As prescribed in 619.202-70(o)(1), insert the following provision: Department of State Mentor-Protégé Program (APR 2004) (a) Large and small...

  3. 48 CFR 652.219-72 - Department of State Mentor-Protégé Program.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false Department of State Mentor....219-72 Department of State Mentor-Protégé Program. As prescribed in 619.202-70(o)(1), insert the following provision: Department of State Mentor-Protégé Program (APR 2004) (a) Large and small...

  4. A mentor-protégé program for new faculty, Part II: Stories of mentors.

    PubMed

    Wilson, Carol B; Brannan, Jane; White, Anne

    2010-12-01

    Mentorship has been identified as an influential factor in retaining new nursing faculty. A mentor-protégé program for novice faculty was implemented to promote development of the protégés in their role as nurse educators. A qualitative research study conducted to illuminate the meaning of experiences of mentors led to the emergence of four patterns: The Significance of the Mentor-Protégé Relationship, Communication as Important Between Mentor and Protégé, The Mentor-Protégé Program-Protégé's Perspectives, and The Mentoring Role as Expert Educator. The data from the study support the significance of providing mentorship to novice or new nurse educators. The data suggest that mentors benefit from participation in a mentor-protégé program as much as the protégés. Similar programs are needed in nursing if we are to mentor and encourage faculty to begin and remain in the role of educators to combat the future nurse educator shortage.

  5. A Mentoring Mindset: Preparing Future Principals to Be Effective Protégés

    ERIC Educational Resources Information Center

    Searby, Linda

    2008-01-01

    Aspiring school leaders do not emerge from their principal preparation programs fully ready for the challenges that await them as new administrators. They will need mentoring. A professor in an educational leadership course developed content which taught students the knowledge, skills and dispositions of protégéship. The Framework for Protégéship…

  6. 48 CFR 1019.202-70-8 - Protégé firms.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Policies 1019.202-70-8 Protégé firms. (a) For selection as a protégé, a firm must be: (1) A small business, women-owned small business, small disadvantaged business, small business owned and controlled by service disabled veterans, or qualified HUBZone small......

  7. MultitaskProtDB: a database of multitasking proteins.

    PubMed

    Hernández, Sergio; Ferragut, Gabriela; Amela, Isaac; Perez-Pons, JosepAntoni; Piñol, Jaume; Mozo-Villarias, Angel; Cedano, Juan; Querol, Enrique

    2014-01-01

    We have compiled MultitaskProtDB, available online at http://wallace.uab.es/multitask, to provide a repository where the many multitasking proteins found in the literature can be stored. Multitasking or moonlighting is the capability of some proteins to execute two or more biological functions. Usually, multitasking proteins are experimentally revealed by serendipity. This ability of proteins to perform multitasking functions helps us to understand one of the ways used by cells to perform many complex functions with a limited number of genes. Even so, the study of this phenomenon is complex because, among other things, there is no database of moonlighting proteins. The existence of such a tool facilitates the collection and dissemination of these important data. This work reports the database, MultitaskProtDB, which is designed as a friendly user web page containing >288 multitasking proteins with their NCBI and UniProt accession numbers, canonical and additional biological functions, monomeric/oligomeric states, PDB codes when available and bibliographic references. This database also serves to gain insight into some characteristics of multitasking proteins such as frequencies of the different pairs of functions, phylogenetic conservation and so forth.

  8. The neXtProt knowledgebase on human proteins: 2017 update

    PubMed Central

    Gaudet, Pascale; Michel, Pierre-André; Zahn-Zabal, Monique; Britan, Aurore; Cusin, Isabelle; Domagalski, Marcin; Duek, Paula D.; Gateau, Alain; Gleizes, Anne; Hinard, Valérie; Rech de Laval, Valentine; Lin, JinJin; Nikitin, Frederic; Schaeffer, Mathieu; Teixeira, Daniel; Lane, Lydie; Bairoch, Amos

    2017-01-01

    The neXtProt human protein knowledgebase (https://www.nextprot.org) continues to add new content and tools, with a focus on proteomics and genetic variation data. neXtProt now has proteomics data for over 85% of the human proteins, as well as new tools tailored to the proteomics community. Moreover, the neXtProt release 2016-08-25 includes over 8000 phenotypic observations for over 4000 variations in a number of genes involved in hereditary cancers and channelopathies. These changes are presented in the current neXtProt update. All of the neXtProt data are available via our user interface and FTP site. We also provide an API access and a SPARQL endpoint for more technical applications. PMID:27899619

  9. The Effect of Mentoring on Protégés' Organizational Deviance.

    PubMed

    Chen, Cheng; Wen, Peng

    2016-08-01

    The aim of the present study was to investigate the effect of mentoring on protégés' organizational deviance. The sample comprised 202 ongoing formal mentoring dyads in the People's Republic of China (mentor samples: 61.9% male, M age = 36.8 years; protégé samples: 57.4% male, M age = 25.0 years). The regression results showed that mentoring was negatively related to protégés' organizational deviance. Moreover, job embeddedness and organizational identification mediated the association between mentoring and protégés' organizational deviance. Furthermore, the perceived developmental climate played a significant moderating role in the relationships between mentoring and job embeddedness and organizational identification such that the relationships were stronger when protégés perceived a stronger developmental climate. The theoretical and practical implications of this study were discussed.

  10. The neXtProt knowledgebase on human proteins: current status

    PubMed Central

    Gaudet, Pascale; Michel, Pierre-André; Zahn-Zabal, Monique; Cusin, Isabelle; Duek, Paula D.; Evalet, Olivier; Gateau, Alain; Gleizes, Anne; Pereira, Mario; Teixeira, Daniel; Zhang, Ying; Lane, Lydie; Bairoch, Amos

    2015-01-01

    neXtProt (http://www.nextprot.org) is a human protein-centric knowledgebase developed at the SIB Swiss Institute of Bioinformatics. Focused solely on human proteins, neXtProt aims to provide a state of the art resource for the representation of human biology by capturing a wide range of data, precise annotations, fully traceable data provenance and a web interface which enables researchers to find and view information in a comprehensive manner. Since the introductory neXtProt publication, significant advances have been made on three main aspects: the representation of proteomics data, an extended representation of human variants and the development of an advanced search capability built around semantic technologies. These changes are presented in the current neXtProt update. PMID:25593349

  11. 48 CFR 1819.7205 - Mentor-protégé agreements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... in— (i) General business management, including organizational management, financial management, personnel management, marketing, business development, and overall business planning; (ii) Engineering... ADMINISTRATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS NASA Mentor-Protégé Program 1819.7205...

  12. LinkProt: a database collecting information about biological links

    PubMed Central

    Dabrowski-Tumanski, Pawel; Jarmolinska, Aleksandra I.; Niemyska, Wanda; Rawdon, Eric J.; Millett, Kenneth C.; Sulkowska, Joanna I.

    2017-01-01

    Protein chains are known to fold into topologically complex shapes, such as knots, slipknots or complex lassos. This complex topology of the chain can be considered as an additional feature of a protein, separate from secondary and tertiary structures. Moreover, the complex topology can be defined also as one additional structural level. The LinkProt database (http://linkprot.cent.uw.edu.pl) collects and displays information about protein links — topologically non-trivial structures made by up to four chains and complexes of chains (e.g. in capsids). The database presents deterministic links (with loops closed, e.g. by two disulfide bonds), links formed probabilistically and macromolecular links. The structures are classified according to their topology and presented using the minimal surface area method. The database is also equipped with basic tools which allow users to analyze the topology of arbitrary (bio)polymers. PMID:27794552

  13. 48 CFR 852.219-72 - Evaluation factor for participation in the VA mentor-protégé program.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... program. As prescribed in 819.7115(b), insert the following clause: Evaluation Factor for Participation in the VA Mentor-Protégé Program (DEC2009) This solicitation contains an evaluation factor or sub-factor regarding participation in the VA Mentor-Protégé Program. In order to receive credit under the...

  14. 48 CFR 852.219-72 - Evaluation factor for participation in the VA mentor-protégé program.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... program. As prescribed in 819.7115(b), insert the following clause: Evaluation Factor for Participation in the VA Mentor-Protégé Program (DEC2009) This solicitation contains an evaluation factor or sub-factor regarding participation in the VA Mentor-Protégé Program. In order to receive credit under the...

  15. 48 CFR 852.219-72 - Evaluation factor for participation in the VA mentor-protégé program.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... program. As prescribed in 819.7115(b), insert the following clause: Evaluation Factor for Participation in the VA Mentor-Protégé Program (DEC2009) This solicitation contains an evaluation factor or sub-factor regarding participation in the VA Mentor-Protégé Program. In order to receive credit under the...

  16. 48 CFR 852.219-72 - Evaluation factor for participation in the VA mentor-protégé program.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... program. As prescribed in 819.7115(b), insert the following clause: Evaluation Factor for Participation in the VA Mentor-Protégé Program (DEC2009) This solicitation contains an evaluation factor or sub-factor regarding participation in the VA Mentor-Protégé Program. In order to receive credit under the...

  17. 76 FR 70828 - Proposed Information Collection (Mentor-Protégé Program Application and Reports) Activity...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-15

    ... needed to establish a mentor-prot g program agreement between a large business, veteran-owned small business and service-disabled veteran-owned small business and to report the success of the program. DATES... will be used to institute a mentor-prot g program whereby large businesses agree to provide...

  18. Indoor/outdoor radon decay products associated aerosol particle-size distributions and their relation to total number concentrations.

    PubMed

    Moriizumi, Jun; Yamada, Shinya; Xu, Yang; Matsuki, Satoru; Hirao, Shigekazu; Yamazawa, Hiromi

    2014-07-01

    The activity size distributions of indoor and outdoor radioactive aerosol associated with short-lived radon decay products were observed at Nagoya, Japan, for some periods from 2010 to 2012, following the indoor observation by Mostafa et al. [Mostafa, A. M. A., Tamaki, K., Moriizumi, J., Yamazawa, H. and Iida, T. The weather dependence of particle size distribution of indoor radioactive aerosol associated with radon decay products. Radiat. Prot. Dosim. 146: (1-3), 19-22 (2011)]. The tendency of smaller indoor activity median aerodynamic diameter (AMAD) after rainfalls showed in the previous study was not consistently obtained, while the consistent tendency of less indoor radioactive particles with diameters in the accumulation mode was observed again after rainfalls. The indoor aerosols showed activity size distributions similar to the outdoor ones. Non-radioactive aerosol particle concentrations measured with a laser particle counter suggested a somewhat liner relationship with AMAD.

  19. LiF:Mg,Ti TLD response as a function of photon energy for moderately filtered x-ray spectra in the range of 20-250 kVp relative to {sup 60}Co

    SciTech Connect

    Nunn, A. A.; Davis, S. D.; Micka, J. A.; DeWerd, L. A.

    2008-05-15

    The response of LiF:Mg,Ti thermoluminescent dosimeters (TLDs) as a function of photon energy was determined using irradiations with moderately filtered x-ray beams in the energy range of 20-250 kVp relative to the response to irradiations with {sup 60}Co photons. To determine if the relative light output from LiF:Mg,Ti TLDs per unit air kerma as a function of photon energy can be predicted using calculations such as Monte Carlo (MC) simulations, measurements from the x-ray beam irradiations were compared with MC calculated results, similar to the methodology used by Davis et al. [Radiat. Prot. Dosim. 106, 33-43 (2003)]. TLDs were irradiated in photon beams with well-known air kerma rates using the National Institute of Standards and Technology traceable M-series x-ray beams in the range of 20-250 kVp. For each x-ray beam, several sets of TLDs were irradiated for times corresponding to different air kerma levels to take into account any dose nonlinearity. TLD light output was then compared to that from several sets of TLDs irradiated at similar corresponding air kerma levels using a {sup 60}Co irradiator. The MC code MCNP5 was used to account for photon scatter and attenuation in the holder and TLDs and was used to calculate the predicted relative TLD light output per unit air kerma for irradiations with each of the experimentally used photon beams. The measured relative TLD response as a function of photon energy differed by up to 13% from the MC calculations. We conclude that MC calculations do not accurately predict the relative response of TLDs as a function of photon energy, consistent with the conclusions of Davis et al. [Radiat. Prot. Dosim. 106, 33-43 (2003)]. This is likely due to complications in the solid state physics of the thermoluminescence process that are not incorporated into the simulation.

  20. Some elements for a revision of the americium reference biokinetic model.

    PubMed

    Blanchardon, E; Leggett, R W; Eckerman, K F

    2007-01-01

    The interpretation of individual activity measurement after a contamination by 241Am or its parent nuclide 241Pu is based on the reference americium (Am) biokinetic model published by the International Commission on Radiological Protection in 1993 [International Commission on Radiological Protection. Age-dependent doses to members of the public from intake of radionuclides: Part 2 Ingestion dose coefficients. ICRP Publication 67. Ann. ICRP 23(3/4) (1993)]. The authors analysed the new data about Am biokinetics reported afterwards to propose an update of the current model. The most interesting results, from the United States Transuranium and Uranium Registries post-mortem measurement database [Filipy, R. E. and Russel, J. J. The United States Transuranium and Uranium Registries as sources for actinide dosimetry and bioeffects. Radiat. Prot. Dosim. 105(1-4), 185-187 (2003)] and the long-term follow-up of cases of inhalation intake [Malátová, I., Foltánová, S., Becková, V., Filgas, R., Pospísilová, H. and Hölgye, Z. Assessment of occupational doses from internal contamination with 241Am. Radiat. Prot. Dosim. 105(1-4), 325-328 (2003)], seemed to show that the current model underestimates the retention in the massive soft tissues and overestimates the retention in the skeleton and the late urinary excretion. However, a critical review of the data demonstrated that all were not equally reliable and suggested that only a slight revision of the model, possibly involving a change in the balance of activity between massive soft tissues, cortical and trabecular bone surfaces, may be required.

  1. Molecular docking analysis of UniProtKB nitrate reductase enzyme with known natural flavonoids

    PubMed Central

    Shaik, Ayub; Thumma, Vishnu; Kotha, Aruna Kumari; Kramadhati, Sandhya; Pochampally, Jalapathy; Bandi, Seshagiri

    2016-01-01

    The functional inference of UniProtKB nitrate reductase enzyme (UniProtKB - P0AF33) through structural modeling is of interest in plant biology. Therefore, a homology model for UniProtKB variant of the enzyme was constructed using available data with the MODELER software tool. The model was further docked with five natural flavonoid structures such as hesperetin, naringenin, leucocyanidin, quercetin and hesperetin triacetate using the AUTODOCK (version 4.2) software tool. The structure aided molecular interactions of these flavonoids with nitrate reductase is documented in this study. The binding features (binding energy (ΔG) value, H bonds and docking score) hesperetin to the enzyme model is relatively high, satisfactory and notable. This data provides valuable insights to the relative binding of several naturally occurring flavonoids to nitrate reductase enzyme and its relevance in plant biology.

  2. 48 CFR 1019.202-70 - The Treasury Mentor-Protégé Program.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false The Treasury Mentor-Protégé Program. 1019.202-70 Section 1019.202-70 Federal Acquisition Regulations System DEPARTMENT OF THE TREASURY SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Policies 1019.202-70 The Treasury...

  3. Students as Protégés: Factors That Lead to Success

    ERIC Educational Resources Information Center

    Bear, Stephen; Jones, Gwen

    2017-01-01

    This study provides insight into the factors that influence satisfaction with an Internet-based practitioner-student mentoring relationship that is part of an undergraduate business school curriculum. Practitioner mentors are especially important because they can help student protégés learn the skills needed for their professional development,…

  4. 48 CFR 852.219-71 - VA mentor-protégé program.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false VA mentor-protégé program. 852.219-71 Section 852.219-71 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Texts of Provisions and Clauses...

  5. 48 CFR 352.219-71 - Mentor-protégé program reporting requirements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Mentor-protégé program reporting requirements. 352.219-71 Section 352.219-71 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Texts of Provisions...

  6. 48 CFR 352.219-70 - Mentor-protégé program.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Mentor-protégé program. 352.219-70 Section 352.219-70 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Texts of Provisions and Clauses...

  7. 48 CFR 1819.7205 - Mentor-protégé agreements.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...://www.osbp.nasa.gov. ... ADMINISTRATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS NASA Mentor-Protégé Program 1819.7205 Mentor... agreement as a condition for award of a contract by the mentor, including a subcontract under a...

  8. 48 CFR 1819.7205 - Mentor-protégé agreements.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...://www.osbp.nasa.gov. ... ADMINISTRATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS NASA Mentor-Protégé Program 1819.7205 Mentor... agreement as a condition for award of a contract by the mentor, including a subcontract under a...

  9. 48 CFR 1819.7205 - Mentor-protégé agreements.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...://www.osbp.nasa.gov. ... ADMINISTRATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS NASA Mentor-Protégé Program 1819.7205 Mentor... agreement as a condition for award of a contract by the mentor, including a subcontract under a...

  10. 48 CFR 1819.7205 - Mentor-protégé agreements.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...://www.osbp.nasa.gov. ... ADMINISTRATION SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS NASA Mentor-Protégé Program 1819.7205 Mentor... agreement as a condition for award of a contract by the mentor, including a subcontract under a...

  11. 48 CFR 719.273-4 - Eligibility of Mentor and Protégé firms.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... INTERNATIONAL DEVELOPMENT SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS The U.S. Agency for International... business entities approved as Mentors may enter into agreements (hereafter referred to as “Mentor-Protégé... subcontractors. Eligible small business entities capable of providing developmental assistance may be approved...

  12. 48 CFR 3052.219-71 - DHS mentor-protégé program.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., which are small businesses, veteran-owned small businesses, service-disabled veteran-owned small businesses, HUBZone small businesses, small disadvantaged businesses, and women-owned small business concerns... providing developmental assistance to eligible small business protégé entities......

  13. Radiation dosimetry.

    PubMed Central

    Cameron, J

    1991-01-01

    This article summarizes the basic facts about the measurement of ionizing radiation, usually referred to as radiation dosimetry. The article defines the common radiation quantities and units; gives typical levels of natural radiation and medical exposures; and describes the most important biological effects of radiation and the methods used to measure radiation. Finally, a proposal is made for a new radiation risk unit to make radiation risks more understandable to nonspecialists. PMID:2040250

  14. Expert curation in UniProtKB: a case study on dealing with conflicting and erroneous data.

    PubMed

    Poux, Sylvain; Magrane, Michele; Arighi, Cecilia N; Bridge, Alan; O'Donovan, Claire; Laiho, Kati

    2014-01-01

    UniProtKB/Swiss-Prot provides expert curation with information extracted from literature and curator-evaluated computational analysis. As knowledgebases continue to play an increasingly important role in scientific research, a number of studies have evaluated their accuracy and revealed various errors. While some are curation errors, others are the result of incorrect information published in the scientific literature. By taking the example of sirtuin-5, a complex annotation case, we will describe the curation procedure of UniProtKB/Swiss-Prot and detail how we report conflicting information in the database. We will demonstrate the importance of collaboration between resources to ensure curation consistency and the value of contributions from the user community in helping maintain error-free resources. Database URL: www.uniprot.org.

  15. Protéger les nourrissons contre la coqueluche

    PubMed Central

    Gilley, Meghan; Goldman, Ran D.

    2014-01-01

    Résumé Question Compte tenu du taux à la hausse de la coqueluche chez les enfants, plusieurs familles m’ont demandé quels moyens prendre pour protéger leurs tout-petits de cette infection. Quelles devraient être mes recommandations à ces familles? Réponse La coqueluche est une maladie évitable qui est endémique dans le monde entier. Chez les adultes, la coqueluche cause une maladie bénigne semblable à un rhume, suivie d’une toux persistante. Chez les nourrissons, elle peut causer de l’apnée, des convulsions, une encéphalopathie, une bronchopneumonie et la mort. Les décès dus à la coqueluche se produisent dans 86 % des cas chez des nourrissons de moins de 4 mois. La stratégie du cocooning, c’est-à-dire la vaccination des adultes en étroit contact avec des nourrissons, est recommandée par de nombreuses agences mondiales et nationales, mais elle ne prévient probablement que 20 % des cas de coqueluche chez les nourrissons. La vaccination durant la grossesse est plus efficace, mais elle n’est pas encore approuvée au Canada. Il n’a pas été démontré que la vaccination à la naissance soit uniformément efficace et elle n’est donc pas recommandée à l’heure actuelle.

  16. Radiation Therapy

    MedlinePlus

    ... Loss Surgery? A Week of Healthy Breakfasts Shyness Radiation Therapy KidsHealth > For Teens > Radiation Therapy A A ... how to cope with side effects. What Is Radiation Therapy? Cancer is a disease that causes cells ...

  17. Radiation Protection

    MedlinePlus

    Jump to main content US EPA United States Environmental Protection Agency Search Search Radiation Protection Share Facebook Twitter Google+ Pinterest Contact Us Radiation Protection Document Library View ...

  18. Atmospheric radiation

    SciTech Connect

    Harshvardhan, M.R. )

    1991-01-01

    Studies of atmospheric radiative processes are summarized for the period 1987-1990. Topics discussed include radiation modeling; clouds and radiation; radiative effects in dynamics and climate; radiation budget and aerosol effects; and gaseous absorption, particulate scattering and surface reflection. It is concluded that the key developments of the period are a defining of the radiative forcing to the climate system by trace gases and clouds, the recognition that cloud microphysics and morphology need to be incorporated not only into radiation models but also climate models, and the isolation of a few important unsolved theoretical problems in atmospheric radiation.

  19. Slow pyrolysis of prot, alkali and dealkaline lignins for production of chemicals.

    PubMed

    Biswas, Bijoy; Singh, Rawel; Kumar, Jitendra; Khan, Adnan Ali; Krishna, Bhavya B; Bhaskar, Thallada

    2016-08-01

    Effect of different lignins were studied during slow pyrolysis. Maximum bio-oil yield of 31.2, 34.1, and 29.5wt.% was obtained at 350, 450 and 350°C for prot lignin, alkali lignin and dealkaline lignin respectively. Maximum yield of phenolic compounds 78%, 80% and 92% from prot lignin, alkali and dealkaline lignin at 350, 450 and 350°C. The differences in the pyrolysis products indicated the source of lignins such as soft and hard wood lignins. The biochar characterisation revealed that the various ether linkages were broken during pyrolysis and lignin was converted into monomeric substituted phenols. Bio-oil showed that the relative contents of each phenolic compound changes significantly with pyrolysis temperature and also the relative contents of each compound changes with different samples.

  20. What Do Hispanic Students Want in a Mentor? A Model of Protégé Cultural Orientation, Mentorship Expectations, and Performance

    ERIC Educational Resources Information Center

    Cox, Cody B.; Yang, Yan; Dicke-Bohmann, Amy K.

    2014-01-01

    The purpose of this study was to propose and test a model of the effects of cultural factors on Hispanic protégés' expectations for and experiences with their mentors. Specifically, the proposed model posits that cultural orientation predicts the mentorship functions protégés desire, and the positive impact of these mentorship functions depends on…

  1. Protégés' Personality Traits, Expectations, the Quality of the Mentoring Relationship and Adjustment: A Big Five Analysis

    ERIC Educational Resources Information Center

    Goldner, Limor

    2016-01-01

    Background: Community-based mentoring interventions can benefit high-risk youth. However, meta-analyses suggest that these benefits may be conditioned by protégés' personality. Objectives: Associations between protégés' personality traits and mentoring expectations, the quality of the mentoring relationship, the perceived mentoring contribution,…

  2. 48 CFR 653.219-71 - DOS form DS-4053, Department of State Mentor-Protégé Program Application.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ..., Department of State Mentor-Protégé Program Application. 653.219-71 Section 653.219-71 Federal Acquisition Regulations System DEPARTMENT OF STATE CLAUSES AND FORMS FORMS Prescription of Forms 653.219-71 DOS form DS-4053, Department of State Mentor-Protégé Program Application. As prescribed in 619.102-70(i),...

  3. 48 CFR 653.219-71 - DOS form DS-4053, Department of State Mentor-Protégé Program Application.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., Department of State Mentor-Protégé Program Application. 653.219-71 Section 653.219-71 Federal Acquisition Regulations System DEPARTMENT OF STATE CLAUSES AND FORMS FORMS Prescription of Forms 653.219-71 DOS form DS-4053, Department of State Mentor-Protégé Program Application. As prescribed in 619.102-70(i),...

  4. 48 CFR 653.219-71 - DOS form DS-4053, Department of State Mentor-Protégé Program Application.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., Department of State Mentor-Protégé Program Application. 653.219-71 Section 653.219-71 Federal Acquisition Regulations System DEPARTMENT OF STATE CLAUSES AND FORMS FORMS Prescription of Forms 653.219-71 DOS form DS-4053, Department of State Mentor-Protégé Program Application. As prescribed in 619.102-70(i),...

  5. 48 CFR 653.219-71 - DOS form DS-4053, Department of State Mentor-Protégé Program Application.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., Department of State Mentor-Protégé Program Application. 653.219-71 Section 653.219-71 Federal Acquisition Regulations System DEPARTMENT OF STATE CLAUSES AND FORMS FORMS Prescription of Forms 653.219-71 DOS form DS-4053, Department of State Mentor-Protégé Program Application. As prescribed in 619.102-70(i),...

  6. 48 CFR 653.219-71 - DOS form DS-4053, Department of State Mentor-Protégé Program Application.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., Department of State Mentor-Protégé Program Application. 653.219-71 Section 653.219-71 Federal Acquisition Regulations System DEPARTMENT OF STATE CLAUSES AND FORMS FORMS Prescription of Forms 653.219-71 DOS form DS-4053, Department of State Mentor-Protégé Program Application. As prescribed in 619.102-70(i),...

  7. 48 CFR 3052.219-72 - Evaluation of prime contractor participation in the DHS mentor-protégé program.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Evaluation of prime contractor participation in the DHS mentor-protégé program. As prescribed in (HSAR) 48... 48 Federal Acquisition Regulations System 7 2011-10-01 2011-10-01 false Evaluation of prime contractor participation in the DHS mentor-protégé program. 3052.219-72 Section 3052.219-72...

  8. 48 CFR 3052.219-72 - Evaluation of prime contractor participation in the DHS mentor-protégé program.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Evaluation of prime contractor participation in the DHS mentor-protégé program. As prescribed in (HSAR) 48... 48 Federal Acquisition Regulations System 7 2014-10-01 2014-10-01 false Evaluation of prime contractor participation in the DHS mentor-protégé program. 3052.219-72 Section 3052.219-72...

  9. 48 CFR 3052.219-72 - Evaluation of prime contractor participation in the DHS mentor-protégé program.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Evaluation of prime contractor participation in the DHS mentor-protégé program. As prescribed in (HSAR) 48... 48 Federal Acquisition Regulations System 7 2012-10-01 2012-10-01 false Evaluation of prime contractor participation in the DHS mentor-protégé program. 3052.219-72 Section 3052.219-72...

  10. 48 CFR 3052.219-72 - Evaluation of prime contractor participation in the DHS mentor-protégé program.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Evaluation of prime contractor participation in the DHS mentor-protégé program. As prescribed in (HSAR) 48... 48 Federal Acquisition Regulations System 7 2013-10-01 2012-10-01 true Evaluation of prime contractor participation in the DHS mentor-protégé program. 3052.219-72 Section 3052.219-72...

  11. 48 CFR 3052.219-72 - Evaluation of prime contractor participation in the DHS mentor-protégé program.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Evaluation of prime contractor participation in the DHS mentor-protégé program. As prescribed in (HSAR) 48... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Evaluation of prime contractor participation in the DHS mentor-protégé program. 3052.219-72 Section 3052.219-72...

  12. 76 FR 25733 - 30-Day Notice of Proposed Information Collection DS 4053, Department of State Mentor-Protégé...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-05

    ... large for-profit companies planning to team together in an official mentor-prot g capacity to improve...-4053. Respondents: Small and large for-profit companies planning to team together in an official mentor-prot g capacity to improve the likelihood of winning DOS contracts. Estimated Number of Respondents:...

  13. 76 FR 1658 - 60-Day Notice of Proposed Information Collection: DS 4053, Department of State Mentor-Protégé...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-11

    ... large for-profit companies planning to team together in an official mentor- prot g capacity to improve...-4053. Respondents: Small and large for-profit companies planning to team together in an official mentor-prot g capacity to improve the likelihood of winning DOS contracts. Estimated Number of Respondents:...

  14. 48 CFR 719.273 - The U.S. Agency for International Development (USAID) Mentor-Protégé Program.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... International Development (USAID) Mentor-Protégé Program. 719.273 Section 719.273 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS The U.S. Agency for International Development (USAID) Mentor-Protégé Program 719.273 The U.S. Agency...

  15. Protótipo do primeiro interferômetro brasileiro - BDA

    NASA Astrophysics Data System (ADS)

    Cecatto, J. R.; Fernandes, F. C. R.; Neri, J. A. C. F.; Bethi, N.; Felipini, N. S.; Madsen, F. R. H.; Andrade, M. C.; Soares, A. C.; Alonso, E. M. B., Sawant, H. S.

    2004-04-01

    A interferometria é uma poderosa ferramenta usada para investigar estruturas espaciais de fontes astrofísicas fornecendo uma riqueza de detalhes inatingível pelas técnicas convencionais de imageamento. Em particular, a interferometria com ondas de rádio abre o horizonte de conhecimento do Universo nesta ampla banda do espectro eletromagnético, que vai de cerca de 20 kHz até centenas de GHz já próximo ao infravermelho, e que está acessível a partir de instrumentos instalados em solo. Neste trabalho, apresentamos o interferômetro designado por Arranjo Decimétrico Brasileiro (BDA). Trata-se do primeiro interferômetro a ser desenvolvido no Brasil e América Latina que já está em operação na fase de protótipo. Apresentamos o desenvolvimento realizado até o momento, o sítio de instalação do instrumento, o protótipo e os principais resultados dos testes de sua operação, as perspectivas futuras e a ciência a ser desenvolvida com o instrumento nas fases II e III. Neste trabalho é dada ênfase ao desenvolvimento, testes de operação e principais resultados do protótipo. É discutida brevemente a ciência que pode ser feita com o instrumento. Tanto os detalhes técnicos quanto os principais parâmetros estimados para o instrumento nas próximas fases de desenvolvimento e o desempenho do protótipo serão publicados em breve.

  16. DisProt 7.0: a major update of the database of disordered proteins.

    PubMed

    Piovesan, Damiano; Tabaro, Francesco; Mičetić, Ivan; Necci, Marco; Quaglia, Federica; Oldfield, Christopher J; Aspromonte, Maria Cristina; Davey, Norman E; Davidović, Radoslav; Dosztányi, Zsuzsanna; Elofsson, Arne; Gasparini, Alessandra; Hatos, András; Kajava, Andrey V; Kalmar, Lajos; Leonardi, Emanuela; Lazar, Tamas; Macedo-Ribeiro, Sandra; Macossay-Castillo, Mauricio; Meszaros, Attila; Minervini, Giovanni; Murvai, Nikoletta; Pujols, Jordi; Roche, Daniel B; Salladini, Edoardo; Schad, Eva; Schramm, Antoine; Szabo, Beata; Tantos, Agnes; Tonello, Fiorella; Tsirigos, Konstantinos D; Veljković, Nevena; Ventura, Salvador; Vranken, Wim; Warholm, Per; Uversky, Vladimir N; Dunker, A Keith; Longhi, Sonia; Tompa, Peter; Tosatto, Silvio C E

    2017-01-04

    The Database of Protein Disorder (DisProt, URL: www.disprot.org) has been significantly updated and upgraded since its last major renewal in 2007. The current release holds information on more than 800 entries of IDPs/IDRs, i.e. intrinsically disordered proteins or regions that exist and function without a well-defined three-dimensional structure. We have re-curated previous entries to purge DisProt from conflicting cases, and also upgraded the functional classification scheme to reflect continuous advance in the field in the past 10 years or so. We define IDPs as proteins that are disordered along their entire sequence, i.e. entirely lack structural elements, and IDRs as regions that are at least five consecutive residues without well-defined structure. We base our assessment of disorder strictly on experimental evidence, such as X-ray crystallography and nuclear magnetic resonance (primary techniques) and a broad range of other experimental approaches (secondary techniques). Confident and ambiguous annotations are highlighted separately. DisProt 7.0 presents classified knowledge regarding the experimental characterization and functional annotations of IDPs/IDRs, and is intended to provide an invaluable resource for the research community for a better understanding structural disorder and for developing better computational tools for studying disordered proteins.

  17. ChemProt-3.0: a global chemical biology diseases mapping

    PubMed Central

    Kringelum, Jens; Kjaerulff, Sonny Kim; Brunak, Søren; Lund, Ole; Oprea, Tudor I.; Taboureau, Olivier

    2016-01-01

    ChemProt is a publicly available compilation of chemical-protein-disease annotation resources that enables the study of systems pharmacology for a small molecule across multiple layers of complexity from molecular to clinical levels. In this third version, ChemProt has been updated to more than 1.7 million compounds with 7.8 million bioactivity measurements for 19 504 proteins. Here, we report the implementation of global pharmacological heatmap, supporting a user-friendly navigation of chemogenomics space. This facilitates the visualization and selection of chemicals that share similar structural properties. In addition, the user has the possibility to search by compound, target, pathway, disease and clinical effect. Genetic variations associated to target proteins were integrated, making it possible to plan pharmacogenetic studies and to suggest human response variability to drug. Finally, Quantitative Structure–Activity Relationship models for 850 proteins having sufficient data were implemented, enabling secondary pharmacological profiling predictions from molecular structure. Database URL: http://potentia.cbs.dtu.dk/ChemProt/ PMID:26876982

  18. DisProt 7.0: a major update of the database of disordered proteins

    PubMed Central

    Piovesan, Damiano; Tabaro, Francesco; Mičetić, Ivan; Necci, Marco; Quaglia, Federica; Oldfield, Christopher J.; Aspromonte, Maria Cristina; Davey, Norman E.; Davidović, Radoslav; Dosztányi, Zsuzsanna; Elofsson, Arne; Gasparini, Alessandra; Hatos, András; Kajava, Andrey V.; Kalmar, Lajos; Leonardi, Emanuela; Lazar, Tamas; Macedo-Ribeiro, Sandra; Macossay-Castillo, Mauricio; Meszaros, Attila; Minervini, Giovanni; Murvai, Nikoletta; Pujols, Jordi; Roche, Daniel B.; Salladini, Edoardo; Schad, Eva; Schramm, Antoine; Szabo, Beata; Tantos, Agnes; Tonello, Fiorella; Tsirigos, Konstantinos D.; Veljković, Nevena; Ventura, Salvador; Vranken, Wim; Warholm, Per; Uversky, Vladimir N.; Dunker, A. Keith; Longhi, Sonia; Tompa, Peter; Tosatto, Silvio C.E.

    2017-01-01

    The Database of Protein Disorder (DisProt, URL: www.disprot.org) has been significantly updated and upgraded since its last major renewal in 2007. The current release holds information on more than 800 entries of IDPs/IDRs, i.e. intrinsically disordered proteins or regions that exist and function without a well-defined three-dimensional structure. We have re-curated previous entries to purge DisProt from conflicting cases, and also upgraded the functional classification scheme to reflect continuous advance in the field in the past 10 years or so. We define IDPs as proteins that are disordered along their entire sequence, i.e. entirely lack structural elements, and IDRs as regions that are at least five consecutive residues without well-defined structure. We base our assessment of disorder strictly on experimental evidence, such as X-ray crystallography and nuclear magnetic resonance (primary techniques) and a broad range of other experimental approaches (secondary techniques). Confident and ambiguous annotations are highlighted separately. DisProt 7.0 presents classified knowledge regarding the experimental characterization and functional annotations of IDPs/IDRs, and is intended to provide an invaluable resource for the research community for a better understanding structural disorder and for developing better computational tools for studying disordered proteins. PMID:27899601

  19. Pelvic radiation - discharge

    MedlinePlus

    Radiation of the pelvis - discharge; Cancer treatment - pelvic radiation; Prostate cancer - pelvic radiation; Ovarian cancer - pelvic radiation; Cervical cancer - pelvic radiation; Uterine cancer - pelvic radiation; Rectal cancer - ...

  20. A legume specific protein database (LegProt) improves the number of identified peptides, confidence scores and overall protein identification success rates for legume proteomics.

    PubMed

    Lei, Zhentian; Dai, Xinbin; Watson, Bonnie S; Zhao, Patrick X; Sumner, Lloyd W

    2011-07-01

    A legume specific protein database (LegProt) has been created containing sequences from seven legume species, i.e., Glycine max, Lotus japonicus, Medicago sativa, Medicago truncatula, Lupinusalbus, Phaseolus vulgaris, and Pisum sativum. The database consists of amino acid sequences translated from predicted gene models and 6-frame translations of tentative consensus (TC) sequences assembled from expressed sequence tags (ESTs) and singleton ESTs. This database was queried using mass spectral data for protein identification and identification success rates were compared to the NCBI nr database. Specifically, Mascot MS/MS ion searches of tandem nano-LC Q-TOFMS/MS mass spectral data showed that relative to the NCBI nr protein database, the LegProt database yielded a 54% increase in the average protein score (i.e., from NCBI nr 480 to LegProt 739) and a 50% increase in the average number of matched peptides (i.e., from NCBI nr 8 to LegProt 12). The overall identification success rate also increased from 88% (NCBI nr) to 93% (LegProt). Mascot peptide mass fingerprinting (PMF) searches of the LegProt database using MALDI-TOFMS data yielded a significant increase in the identification success rate from 19% (NCBI nr) to 34% (LegProt) while the average scores and average number of matched peptides showed insignificant changes. The results demonstrate that the LegProt database significantly increases legume protein identification success rates and the confidence levels compared to the commonly used NCBI nr. These improvements are primarily due to the presence of a large number of legume specific TC sequences in the LegProt database that were not found in NCBI nr. The LegProt database is freely available for download (http://bioinfo.noble.org/manuscript-support/legumedb) and will serve as a valuable resource for legume proteomics.

  1. Space Radiation

    NASA Technical Reports Server (NTRS)

    Wu, Honglu

    2006-01-01

    Astronauts receive the highest occupational radiation exposure. Effective protections are needed to ensure the safety of astronauts on long duration space missions. Increased cancer morbidity or mortality risk in astronauts may be caused by occupational radiation exposure. Acute and late radiation damage to the central nervous system (CNS) may lead to changes in motor function and behavior, or neurological disorders. Radiation exposure may result in degenerative tissue diseases (non-cancer or non-CNS) such as cardiac, circulatory, or digestive diseases, as well as cataracts. Acute radiation syndromes may occur due to occupational radiation exposure.

  2. Radiation Proctopathy

    PubMed Central

    Grodsky, Marc B.; Sidani, Shafik M.

    2015-01-01

    Radiation therapy is a widely utilized treatment modality for pelvic malignancies, including prostate cancer, rectal cancer, and cervical cancer. Given its fixed position in the pelvis, the rectum is at a high risk for injury secondary to ionizing radiation. Despite advances made in radiation science, up to 75% of the patients will suffer from acute radiation proctitis and up to 20% may experience chronic symptoms. Symptoms can be variable and include diarrhea, bleeding, incontinence, and fistulization. A multitude of treatment options exist. This article summarizes the latest knowledge relating to radiation proctopathy focusing on the vast array of treatment options. PMID:26034407

  3. 48 CFR 1052.219-73 - Department of the Treasury Mentor-Protégé Program.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Department of the Treasury... DEPARTMENT OF THE TREASURY CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Texts of Provisions and Clauses 1052.219-73 Department of the Treasury Mentor-Protégé Program. As described in DTAR...

  4. 48 CFR 852.219-72 - Evaluation factor for participation in the VA mentor-protégé program.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... the VA Mentor-Protégé Program (DEC2009) This solicitation contains an evaluation factor or sub-factor... factor or sub-factor, the offeror must provide with its proposal a copy of a signed letter issued by...

  5. 13 CFR 124.520 - What are the rules governing SBA's Mentor/Protégé program?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... the filings required by the Securities and Exchange Commission for the past three years. (4) Once... the proposed mentor/protégé agreement and provide any additional information and documentation... addressing the developmental needs of the protege and addressing any problems encountered. (2) The...

  6. 48 CFR 619.202-70 - The Department of State Mentor-Protégé Program.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Small Business Act (15 U.S.C. 637(d)(4)(E)), DOS is authorized to provide appropriate incentives to...) Must be eligible for award of U.S. Government contracts; (3) Must be able to provide developmental... supplies to be provided by the protégé to the mentor; and, (iii) Eligible for award of U.S....

  7. Race and Gender Mentor-Protégé Pairings of Resident Assistants: An Exploration on Leadership Capacity

    ERIC Educational Resources Information Center

    Early, Sherry L.

    2017-01-01

    The leadership capacity of resident assistants can be impacted by many experiences, including involvement in mentoring relationships. The purpose of this study was to examine if and how resident assistants' leadership capacities are influenced by participating in mentoring relationships. Additionally, mentor-protégé race and gender pairings were…

  8. ProtSA: a web application for calculating sequence specific protein solvent accessibilities in the unfolded ensemble

    PubMed Central

    Estrada, Jorge; Bernadó, Pau; Blackledge, Martin; Sancho, Javier

    2009-01-01

    Background The stability of proteins is governed by the heat capacity, enthalpy and entropy changes of folding, which are strongly correlated to the change in solvent accessible surface area experienced by the polypeptide. While the surface exposed in the folded state can be easily determined, accessibilities for the unfolded state at the atomic level cannot be obtained experimentally and are typically estimated using simplistic models of the unfolded ensemble. A web application providing realistic accessibilities of the unfolded ensemble of a given protein at the atomic level will prove useful. Results ProtSA, a web application that calculates sequence-specific solvent accessibilities of the unfolded state ensembles of proteins has been developed and made freely available to the scientific community. The input is the amino acid sequence of the protein of interest. ProtSA follows a previously published calculation protocol which uses the Flexible-Meccano algorithm to generate unfolded conformations representative of the unfolded ensemble of the protein, and uses the exact analytical software ALPHASURF to calculate atom solvent accessibilities, which are averaged on the ensemble. Conclusion ProtSA is a novel tool for the researcher investigating protein folding energetics. The sequence specific atom accessibilities provided by ProtSA will allow obtaining better estimates of the contribution of the hydrophobic effect to the free energy of folding, will help to refine existing parameterizations of protein folding energetics, and will be useful to understand the influence of point mutations on protein stability. PMID:19356231

  9. Untangling Protégé Self-Reports of Mentoring Functions: Further Meta-Analytic Understanding

    ERIC Educational Resources Information Center

    Dickson, Jubilee; Kirkpatrick-Husk, Katie; Kendall, Dana; Longabaugh, James; Patel, Ajal; Scielzo, Shannon

    2014-01-01

    In the current study, we sought to further our understanding of the relations between various types of protégé-reported mentoring functions (psychosocial and career support and role modeling [RM]) by conducting a meta-analysis. We examined the relationships among these functions and investigated their relationships with expected mentorship…

  10. 13 CFR 124.520 - What are the rules governing SBA's Mentor/Protégé program?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... plan, and to improve its ability to successfully compete for contracts. (b) Mentors. Any concern or non... due to lessons learned and practical experience gained because of the 8(a) BD program, or through its... protégé firm meet the goals established in its SBA-approved business plan; (ii) Establish a single...

  11. 13 CFR 124.520 - What are the rules governing SBA's Mentor/Protégé program?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... plan, and to improve its ability to successfully compete for contracts. (b) Mentors. Any concern or non... due to lessons learned and practical experience gained because of the 8(a) BD program, or through its... protégé firm meet the goals established in its SBA-approved business plan; (ii) Establish a single...

  12. Radiator technology

    NASA Technical Reports Server (NTRS)

    Juhasz, Albert J.

    1993-01-01

    Radiator technology is discussed in the context of the Civilian Space Technology Initiative's (CSTI's) high capacity power-thermal management project. The CSTI project is a subset of a project to develop a piloted Mars nuclear electric propulsion (NEP) vehicle. The following topics are presented in vugraph form: advanced radiator concepts; heat pipe codes and testing; composite materials; radiator design and integration; and surface morphology.

  13. Hawking radiation

    NASA Astrophysics Data System (ADS)

    Parentani, Renaud; Spindel, Philippe

    2011-12-01

    Hawking radiation is the thermal radiation predicted to be spontaneously emitted by black holes. It arises from the steady conversion of quantum vacuum fluctuations into pairs of particles, one of which escaping at infinity while the other is trapped inside the black hole horizon. It is named after the physicist Stephen Hawking who derived its existence in 1974. This radiation reduces the mass of black holes and is therefore also known as black hole evaporation.

  14. FireProt: Energy- and Evolution-Based Computational Design of Thermostable Multiple-Point Mutants

    PubMed Central

    Sebestova, Eva; Bendl, Jaroslav; Khare, Sagar; Chaloupkova, Radka; Prokop, Zbynek; Brezovsky, Jan; Baker, David; Damborsky, Jiri

    2015-01-01

    There is great interest in increasing proteins’ stability to enhance their utility as biocatalysts, therapeutics, diagnostics and nanomaterials. Directed evolution is a powerful, but experimentally strenuous approach. Computational methods offer attractive alternatives. However, due to the limited reliability of predictions and potentially antagonistic effects of substitutions, only single-point mutations are usually predicted in silico, experimentally verified and then recombined in multiple-point mutants. Thus, substantial screening is still required. Here we present FireProt, a robust computational strategy for predicting highly stable multiple-point mutants that combines energy- and evolution-based approaches with smart filtering to identify additive stabilizing mutations. FireProt’s reliability and applicability was demonstrated by validating its predictions against 656 mutations from the ProTherm database. We demonstrate that thermostability of the model enzymes haloalkane dehalogenase DhaA and γ-hexachlorocyclohexane dehydrochlorinase LinA can be substantially increased (ΔT m = 24°C and 21°C) by constructing and characterizing only a handful of multiple-point mutants. FireProt can be applied to any protein for which a tertiary structure and homologous sequences are available, and will facilitate the rapid development of robust proteins for biomedical and biotechnological applications. PMID:26529612

  15. SubCellProt: predicting protein subcellular localization using machine learning approaches.

    PubMed

    Garg, Prabha; Sharma, Virag; Chaudhari, Pradeep; Roy, Nilanjan

    2009-01-01

    High-throughput genome sequencing projects continue to churn out enormous amounts of raw sequence data. However, most of this raw sequence data is unannotated and, hence, not very useful. Among the various approaches to decipher the function of a protein, one is to determine its localization. Experimental approaches for proteome annotation including determination of a protein's subcellular localizations are very costly and labor intensive. Besides the available experimental methods, in silico methods present alternative approaches to accomplish this task. Here, we present two machine learning approaches for prediction of the subcellular localization of a protein from the primary sequence information. Two machine learning algorithms, k Nearest Neighbor (k-NN) and Probabilistic Neural Network (PNN) were used to classify an unknown protein into one of the 11 subcellular localizations. The final prediction is made on the basis of a consensus of the predictions made by two algorithms and a probability is assigned to it. The results indicate that the primary sequence derived features like amino acid composition, sequence order and physicochemical properties can be used to assign subcellular localization with a fair degree of accuracy. Moreover, with the enhanced accuracy of our approach and the definition of a prediction domain, this method can be used for proteome annotation in a high throughput manner. SubCellProt is available at www.databases.niper.ac.in/SubCellProt.

  16. Teachable Agents and the Protégé Effect: Increasing the Effort Towards Learning

    NASA Astrophysics Data System (ADS)

    Chase, Catherine C.; Chin, Doris B.; Oppezzo, Marily A.; Schwartz, Daniel L.

    2009-08-01

    Betty's Brain is a computer-based learning environment that capitalizes on the social aspects of learning. In Betty's Brain, students instruct a character called a Teachable Agent (TA) which can reason based on how it is taught. Two studies demonstrate the protégé effect: students make greater effort to learn for their TAs than they do for themselves. The first study involved 8th-grade students learning biology. Although all students worked with the same Betty's Brain software, students in the TA condition believed they were teaching their TAs, while in another condition, they believed they were learning for themselves. TA students spent more time on learning activities (e.g., reading) and also learned more. These beneficial effects were most pronounced for lower achieving children. The second study used a verbal protocol with 5th-grade students to determine the possible causes of the protégé effect. As before, students learned either for their TAs or for themselves. Like study 1, students in the TA condition spent more time on learning activities. These children treated their TAs socially by attributing mental states and responsibility to them. They were also more likely to acknowledge errors by displaying negative affect and making attributions for the causes of failures. Perhaps having a TA invokes a sense of responsibility that motivates learning, provides an environment in which knowledge can be improved through revision, and protects students' egos from the psychological ramifications of failure.

  17. Radiation Therapy

    MedlinePlus

    ... can watch you during the procedure. As you go through radiation treatment, you may feel like you're all ... treatment. Avoid exposing the treated area to the sun during the weeks you're getting radiation therapy. And when the treatment's over, wear sunscreen ...

  18. Understanding Radiation.

    ERIC Educational Resources Information Center

    Department of Energy, Washington, DC. Nuclear Energy Office.

    Radiation is a natural energy force that has been a part of the environment since the Earth was formed. It takes various forms, none of which can be smelled, tasted, seen, heard, or felt. Nevertheless, scientists know what it is, where it comes from, how to measure and detect it, and how it affects people. Cosmic radiation from outer space and…

  19. Radiation Therapy

    MedlinePlus

    ... Tumors In Children Pediatric Brain Tumor Diagnosis Family Impact Late Effects After Treatment Returning to School Pediatric ... Una publicación de ABTA en español. Radiation Imaging Technology Information on Radiation and Imaging Technology Home Donor and ...

  20. Radiation Therapy

    MedlinePlus

    ... them from spreading. About half of all cancer patients receive it. The radiation may be external, from special machines, or internal, from radioactive substances that a doctor places inside your body. The type of radiation therapy you receive depends on many factors, including The ...

  1. Radiation Exposure

    MedlinePlus

    ... particles. It occurs naturally in sunlight. Man-made radiation is used in X-rays, nuclear weapons, nuclear power plants and cancer treatment. If you are exposed to small amounts of radiation over a long time, it raises your risk ...

  2. Radiation detector

    DOEpatents

    Fultz, B.T.

    1980-12-05

    Apparatus is provided for detecting radiation such as gamma rays and x-rays generated in backscatter Moessbauer effect spectroscopy and x-ray spectrometry, which has a large window for detecting radiation emanating over a wide solid angle from a specimen and which generates substantially the same output pulse height for monoenergetic radiation that passes through any portion of the detection chamber. The apparatus includes a substantially toroidal chamber with conductive walls forming a cathode, and a wire anode extending in a circle within the chamber with the anode lying closer to the inner side of the toroid which has the least diameter than to the outer side. The placement of the anode produces an electric field, in a region close to the anode, which has substantially the same gradient in all directions extending radially from the anode, so that the number of avalanche electrons generated by ionizing radiation is independent of the path of the radiation through the chamber.

  3. Radiation detector

    DOEpatents

    Fultz, Brent T.

    1983-01-01

    Apparatus is provided for detecting radiation such as gamma rays and X-rays generated in backscatter Mossbauer effect spectroscopy and X-ray spectrometry, which has a large "window" for detecting radiation emanating over a wide solid angle from a specimen and which generates substantially the same output pulse height for monoenergetic radiation that passes through any portion of the detection chamber. The apparatus includes a substantially toroidal chamber with conductive walls forming a cathode, and a wire anode extending in a circle within the chamber with the anode lying closer to the inner side of the toroid which has the least diameter than to the outer side. The placement of the anode produces an electric field, in a region close to the anode, which has substantially the same gradient in all directions extending radially from the anode, so that the number of avalanche electrons generated by ionizing radiation is independent of the path of the radiation through the chamber.

  4. Radiation retinopathy.

    PubMed Central

    Zamber, R W; Kinyoun, J L

    1992-01-01

    Radiation therapy is effective against many cancerous and noncancerous disease processes. As with other therapeutics, side effects must be anticipated, recognized, and managed appropriately. Radiation retinopathy is a vision-threatening complication of ocular, orbital, periorbital, facial, nasopharyngeal, and cranial irradiation. Factors that appear important in the pathogenesis of radiation retinopathy include total radiation dosage, fraction size, concomitant chemotherapy, and preexisting vascular disorders. Clinical manifestations of the disorder include macular edema and nonproliferative and proliferative retinopathy, similar to changes seen in diabetic retinopathy. Argon laser photocoagulation has proved efficacious for managing macular edema and fibrovascular proliferation in some of these patients. Ongoing basic laboratory and clinical research efforts have led to a better understanding of the pathogenesis, natural history, and treatment response of radiation retinopathy. The ultimate goal of this knowledge is to improve the prevention, recognition, and management of this vision-threatening complication. Images PMID:1441494

  5. Diffuse radiation

    NASA Technical Reports Server (NTRS)

    1981-01-01

    A diffuse celestial radiation which is isotropic at least on a course scale were measured from the soft X-ray region to about 150 MeV, at which energy the intensity falls below that of the galactic emission for most galactic latitudes. The spectral shape, the intensity, and the established degree of isotropy of this diffuse radiation already place severe constraints on the possible explanations for this radiation. Among the extragalactic theories, the more promising explanations of the isotropic diffuse emission appear to be radiation from exceptional galaxies from matter antimatter annihilation at the boundaries of superclusters of galaxies of matter and antimatter in baryon symmetric big bang models. Other possible sources for extragalactic diffuse gamma radiation are discussed and include normal galaxies, clusters of galaxies, primordial cosmic rays interacting with intergalactic matter, primordial black holes, and cosmic ray leakage from galaxies.

  6. [Radiation carcinogenesis].

    PubMed

    Hosoi, Yoshio

    2013-11-01

    Misrepair of DNA damage induced by ionizing radiation is a potential cause of carcinogenesis following exposure to radiation. Radiation exposure increases the incidence of the same types of mutations that occur spontaneously in a given population. A high incidence of DNA double-strand breaks is characteristic of damage by ionizing radiation compared with those induced by other environmental mutagens. In China, residents living in areas with high level background radiation(6mSv/y) had a significantly higher frequency of dicentric and ring chromosomes compared to that for the residents living in the control areas(2mSv/y). Radiation-associated increases in risk were seen for most sites. Gender-averaged excess absolute risk rates estimated at age 70, after exposure at age 30, differ in the sites, and the risks of gastric cancer, breast cancer, colon cancer, and lung cancer were highly increased, in that order. Latent periods for the development of leukemia and thyroid cancer after radiation exposure at ages younger than 18 were shorter compared to those for other solid cancers.

  7. Radiation dosimeter

    DOEpatents

    Fox, R.J.

    1981-09-01

    A radiation detector readout circuit is provided which produces a radiation dose-rate readout from a detector even through the detector output may be highly energy dependent. A linear charge amplifier including an output charge pump circuit amplifies the charge signal pulses from the detector and pumps the charge into a charge storage capacitor. The discharge rate of the capacitor through a resistor is controlled to provide a time-dependent voltage which when integrated provides an output proportional to the dose-rate of radiation detected by the detector. This output may be converted to digital form for readout on a digital display.

  8. Radiation dosimeter

    DOEpatents

    Fox, Richard J.

    1983-01-01

    A radiation detector readout circuit is provided which produces a radiation dose-rate readout from a detector even though the detector output may be highly energy dependent. A linear charge amplifier including an output charge pump circuit amplifies the charge signal pulses from the detector and pumps the charge into a charge storage capacitor. The discharge rate of the capacitor through a resistor is controlled to provide a time-dependent voltage which when integrated provides an output proportional to the dose-rate of radiation detected by the detector. This output may be converted to digital form for readout on a digital display.

  9. Radiation Hydrodynamics

    SciTech Connect

    Castor, J I

    2003-10-16

    The discipline of radiation hydrodynamics is the branch of hydrodynamics in which the moving fluid absorbs and emits electromagnetic radiation, and in so doing modifies its dynamical behavior. That is, the net gain or loss of energy by parcels of the fluid material through absorption or emission of radiation are sufficient to change the pressure of the material, and therefore change its motion; alternatively, the net momentum exchange between radiation and matter may alter the motion of the matter directly. Ignoring the radiation contributions to energy and momentum will give a wrong prediction of the hydrodynamic motion when the correct description is radiation hydrodynamics. Of course, there are circumstances when a large quantity of radiation is present, yet can be ignored without causing the model to be in error. This happens when radiation from an exterior source streams through the problem, but the latter is so transparent that the energy and momentum coupling is negligible. Everything we say about radiation hydrodynamics applies equally well to neutrinos and photons (apart from the Einstein relations, specific to bosons), but in almost every area of astrophysics neutrino hydrodynamics is ignored, simply because the systems are exceedingly transparent to neutrinos, even though the energy flux in neutrinos may be substantial. Another place where we can do ''radiation hydrodynamics'' without using any sophisticated theory is deep within stars or other bodies, where the material is so opaque to the radiation that the mean free path of photons is entirely negligible compared with the size of the system, the distance over which any fluid quantity varies, and so on. In this case we can suppose that the radiation is in equilibrium with the matter locally, and its energy, pressure and momentum can be lumped in with those of the rest of the fluid. That is, it is no more necessary to distinguish photons from atoms, nuclei and electrons, than it is to distinguish

  10. Measurement of dose equivalent distribution on-board commercial jet aircraft.

    PubMed

    Kubančák, J; Ambrožová, I; Ploc, O; Pachnerová Brabcová, K; Štěpán, V; Uchihori, Y

    2014-12-01

    The annual effective doses of aircrew members often exceed the limit of 1 mSv for the public due to the increased level of cosmic radiation at the flight altitudes, and thus, it is recommended to monitor them [International Commission on Radiation Protection. 1990 Recommendations of the International Commission on Radiological Protection. ICRP Publication 60. Ann. ICRP 21: (1-3), (1991)]. According to the Monte Carlo simulations [Battistoni, G., Ferrari, A., Pelliccioni, M. and Villari, R. Evaluation of the doses to aircrew members taking into consideration the aircraft structures. Adv. Space Res. 36: , 1645-1652 (2005) and Ferrari, A., Pelliccioni, M. and Villari, R. Evaluation of the influence of aircraft shielding on the aircrew exposure through an aircraft mathematical model. Radiat. Prot. Dosim. 108: (2), 91-105 (2004)], the ambient dose equivalent rate Ḣ*(10) depends on the location in the aircraft. The aim of this article is to experimentally evaluate Ḣ*(10) on-board selected types of aircraft. The authors found that Ḣ*(10) values are higher in the front and the back of the cabin and lesser in the middle of the cabin. Moreover, total dosimetry characteristics obtained in this way are in a reasonable agreement with other data, in particular with the above-mentioned simulations.

  11. Radiation therapy

    MedlinePlus

    ... Intensity-modulated radiotherapy (IMRT) Image-guided radiotherapy (IGRT) Proton therapy is another kind of radiation used to ... than using x-rays to destroy cancer cells, proton therapy uses a beam of special particles called ...

  12. RADIATION DETECTOR

    DOEpatents

    Wilson, H.N.; Glass, F.M.

    1960-05-10

    A radiation detector of the type is described wherein a condenser is directly connected to the electrodes for the purpose of performing the dual function of a guard ring and to provide capacitance coupling for resetting the detector system.

  13. Radiation Basics

    MedlinePlus

    ... of the heaviest radioactive elements, such as uranium , radium and polonium. Even though alpha particles are very ... is roughly the activity of one gram of Radium-226. Curies are not used to measure radiation ...

  14. Radiation Transport

    SciTech Connect

    Urbatsch, Todd James

    2015-06-15

    We present an overview of radiation transport, covering terminology, blackbody raditation, opacities, Boltzmann transport theory, approximations to the transport equation. Next we introduce several transport methods. We present a section on Caseology, observing transport boundary layers. We briefly broach topics of software development, including verification and validation, and we close with a section on high energy-density experiments that highlight and support radiation transport.

  15. Prediction of G Protein-Coupled Receptors with SVM-Prot Features and Random Forest

    PubMed Central

    Ju, Ying

    2016-01-01

    G protein-coupled receptors (GPCRs) are the largest receptor superfamily. In this paper, we try to employ physical-chemical properties, which come from SVM-Prot, to represent GPCR. Random Forest was utilized as classifier for distinguishing them from other protein sequences. MEME suite was used to detect the most significant 10 conserved motifs of human GPCRs. In the testing datasets, the average accuracy was 91.61%, and the average AUC was 0.9282. MEME discovery analysis showed that many motifs aggregated in the seven hydrophobic helices transmembrane regions adapt to the characteristic of GPCRs. All of the above indicate that our machine-learning method can successfully distinguish GPCRs from non-GPCRs. PMID:27529053

  16. Radiation enteritis.

    PubMed

    Harb, Ali H; Abou Fadel, Carla; Sharara, Ala I

    2014-01-01

    Radiation enteritis continues to be a major health concern in recipients of radiation therapy. The incidence of radiation enteritis is expected to continue to rise during the coming years paralleling the unprecedented use of radiotherapy in pelvic cancers. Radiation enteritis can present as either an acute or chronic syndrome. The acute form presents within hours to days of radiation exposure and typically resolves within few weeks. The chronic form may present as early as 2 months or as long as 30 years after exposure. Risk factors can be divided into patient and treatment-related factors. Chronic radiation enteritis is characterized by progressive obliterative endarteritis with exaggerated submucosal fibrosis and can manifest by stricturing, formation of fistulae, local abscesses, perforation, and bleeding. In the right clinical context, diagnosis can be confirmed by cross-sectional imaging, flexible or video capsule endoscopy. Present treatment strategies are directed primarily towards symptom relief and management of emerging complications. Recently, however, there has been a shift towards rational drug design based on improved understanding of the molecular basis of disease in an effort to limit the fibrotic process and prevent organ damage.

  17. ProtEx: a novel technology to display exogenous proteins on the cell surface for immunomodulation.

    PubMed

    Singh, Narendra P; Yolcu, Esma S; Askenasy, Nadir; Shirwan, Haval

    2005-11-01

    Gene therapy as an immunomodulatory approach has the potential to treat various inherited and acquired immune-based human diseases. However, its clinical application has several challenges, varying from the efficiency of gene transfer, control of gene expression, cell and tissue targeting, and safety concerns associated with the introduction of exogenous DNA into cells/tissues. Gene therapy is also a time- and labor-intensive procedure. As an alternative, we recently developed a novel technology, ProtEx, that allows for rapid, efficient, and durable display of exogenous proteins on the surface of cells, tissues, and organs without detectable toxicity. This technology exploits the strong binding affinity (Kd = 10(-15) M) of streptavidin with biotin and involves generation of chimeric molecules composed of the extracellular portions of immunological proteins of interest and a modified form of streptavidin, biotinylation of biological surfaces, and decoration of the modified surface with chimeric proteins. Biotin persists on the cell surface for weeks both in vitro and in vivo, thereby providing a platform to display exogenous proteins with extended cell surface kinetics. Two chimeric proteins, rat FasL (SA-FasL) and human CD80 (CD80-SA), were generated and tested for cell surface display and immunomodulatory functions. SA-FasL and CD80-SA molecules persisted on the surface of various cell types for extended periods, varying from days to weeks in vitro and in vivo. The cell surface kinetics, however, were protein and cell type dependent. SA-FasL showed potent apoptotic activity against Fas+ cells as a soluble protein or displayed on the cell surface and effectively blocked alloreactive responses. The display of CD80-SA on the surface of tumor cells, however, converted them into antigen-presenting cells for effective stimulation of autologous and allogeneic T-cell responses. ProtEx technology, therefore, represents a practical and effective alternative to DNA

  18. Development, implementation and evaluation of a peer review of teaching (PRoT) initiative in nursing education.

    PubMed

    Mager, Diana R; Kazer, Meredith W; Conelius, Jaclyn; Shea, Joyce; Lippman, Doris T; Torosyan, Roben; Nantz, Kathryn

    2014-06-03

    For many years, an area of research in higher education has been emerging around the development and implementation of fair and effective peer evaluation programs. Recently, a new body of knowledge has developed regarding the development and implementation of fair and effective peer evaluation programs resulting in formative and summative evaluations. The purpose of this article is to describe the development, implementation, and evaluation of a peer review of teaching (PRoT) program for nursing faculty, initiated at one small comprehensive university in the northeastern United States. Pairs of nursing faculty evaluated each other's teaching, syllabi, and course materials after collaborating in a pre-evaluation conference to discuss goals of the classroom visit. Qualitative data gathered in post project focus groups revealed that faculty found their modified PRoT process to be a mutually beneficial experience that was more useful, flexible and collegial, and less stressful than their previous evaluation process.

  19. Synchrotron radiation with radiation reaction

    NASA Astrophysics Data System (ADS)

    Nelson, Robert W.; Wasserman, Ira

    1991-04-01

    A rigorous discussion is presented of the classical motion of a relativistic electron in a magnetic field and the resulting electromagnetic radiation when radiation reaction is important. In particular, for an electron injected with initial energy gamma(0), a systematic perturbative solution to the Lorentz-Dirac equation of motion is developed for field strengths satisfying gamma(0) B much less than 6 x 10 to the 15th G. A particularly accurate solution to the electron orbital motion in this regime is found and it is demonstrated how lowest-order corrections can be calculated. It is shown that the total energy-loss rate corresponds to what would be found using the exact Larmor power formula without including radiation reaction. Provided that the particle energy and field strength satisfy the same contraint, it is explicitly demonstrated that the intuitive prescription for calculating the time-integrated radiation spectrum described above is correct.

  20. Brain radiation - discharge

    MedlinePlus

    Radiation - brain - discharge; Cancer-brain radiation; Lymphoma - brain radiation; Leukemia - brain radiation ... Decadron) while you are getting radiation to the brain. It may make you hungrier, cause leg swelling ...

  1. Radiation myelopathy.

    PubMed Central

    Sanyal, B; Pant, G C; Subrahmaniyam, K; Agrawal, M S; Mohanty, S

    1979-01-01

    Five cases of radiation myelopathy were found in a total of 10,000 cases given radiotherapy from 1968 to 1977. The clinical presentation and treatment details including the total dose, treatment volume, number of fractionations, overall time, and the RET value at the spinal cord were calculated and compared with other reports on this subject. The total number of fractionations ranged from 20 to 26 with an overall time of 32 days to 37 days. The dose received by four patients ranged from 1030 to 1900 RET, a little higher than the tolerance level of the spinal cord as compared to reported values. Two patients in this series had high blood pressure. The incidence of radiation myelopathy, already acceptably low, could possibly be reduced further by meticulous planning of radiation. PMID:448380

  2. Radiation effects.

    PubMed

    Preston, R J

    2012-01-01

    International Commission on Radiological Protection (ICRP) Committee 1 (C1) considers the risk of induction of cancer and heritable disease; the underlying mechanisms of radiation action; and the risks, severity, and mechanisms of induction of tissue reactions (formerly 'deterministic effects'). C1 relies upon the interpretation of current knowledge of radio-epidemiological studies; current information on the underlying mechanisms of diseases and radiation-induced disease; and current radiobiological studies at the whole animal, tissue, cell, and molecular levels. This overview will describe the activities of C1 in the context of the 2007 Recommendations of ICRP. In particular, the conclusions from the most recent C1 Task Group deliberations on radon and lung cancer, and tissue reactions will be discussed. Other activities are described in summary fashion to illustrate those areas that C1 judge to be likely to influence the development of the risk estimates and nominal risk coefficients used for radiation protection purposes.

  3. Radiation receiver

    DOEpatents

    Hunt, A.J.

    1983-09-13

    The apparatus for collecting radiant energy and converting same to alternate energy form includes a housing having an interior space and a radiation transparent window allowing, for example, solar radiation to be received in the interior space of the housing. Means are provided for passing a stream of fluid past said window and for injecting radiation absorbent particles in said fluid stream. The particles absorb the radiation and because of their very large surface area, quickly release the heat to the surrounding fluid stream. The fluid stream particle mixture is heated until the particles vaporize. The fluid stream is then allowed to expand in, for example, a gas turbine to produce mechanical energy. In an aspect of the present invention properly sized particles need not be vaporized prior to the entrance of the fluid stream into the turbine, as the particles will not damage the turbine blades. In yet another aspect of the invention, conventional fuel injectors are provided to inject fuel into the fluid stream to maintain the proper temperature and pressure of the fluid stream should the source of radiant energy be interrupted. In yet another aspect of the invention, an apparatus is provided which includes means for providing a hot fluid stream having hot particles disbursed therein which can radiate energy, means for providing a cooler fluid stream having cooler particles disbursed therein, which particles can absorb radiant energy and means for passing the hot fluid stream adjacent the cooler fluid stream to warm the cooler fluid and cooler particles by the radiation from the hot fluid and hot particles. 5 figs.

  4. Radiation receiver

    DOEpatents

    Hunt, Arlon J.

    1983-01-01

    The apparatus for collecting radiant energy and converting same to alternate energy form includes a housing having an interior space and a radiation transparent window allowing, for example, solar radiation to be received in the interior space of the housing. Means are provided for passing a stream of fluid past said window and for injecting radiation absorbent particles in said fluid stream. The particles absorb the radiation and because of their very large surface area, quickly release the heat to the surrounding fluid stream. The fluid stream particle mixture is heated until the particles vaporize. The fluid stream is then allowed to expand in, for example, a gas turbine to produce mechanical energy. In an aspect of the present invention properly sized particles need not be vaporized prior to the entrance of the fluid stream into the turbine, as the particles will not damage the turbine blades. In yet another aspect of the invention, conventional fuel injectors are provided to inject fuel into the fluid stream to maintain the proper temperature and pressure of the fluid stream should the source of radiant energy be interrupted. In yet another aspect of the invention, an apparatus is provided which includes means for providing a hot fluid stream having hot particles disbursed therein which can radiate energy, means for providing a cooler fluid stream having cooler particles disbursed therein, which particles can absorb radiant energy and means for passing the hot fluid stream adjacent the cooler fluid stream to warm the cooler fluid and cooler particles by the radiation from the hot fluid and hot particles.

  5. RADIATION SOURCES

    DOEpatents

    Brucer, M.H.

    1958-04-15

    A novel long-lived source of gamma radiation especially suitable for calibration purposes is described. The source of gamma radiation is denoted mock iodine131, which comprises a naixture of barium-133 and cesium-137. The barium and cesium are present in a barium-cesium ratio of approximately 5.7/1 to 14/1, uniformly dispersed in an ion exchange resin and a filter surrounding the resin comprised of a material of atomic number below approximately 51, and substantially 0.7 to 0.9 millimeter thick.

  6. Radiation dermatitis

    SciTech Connect

    Shack, R.B.; Lynch, J.B.

    1987-04-01

    Even in this era of modern radiotherapy, injuries associated with the medical and industrial use of radiation devices will continue to pose a difficult problem for the reconstructive surgeon. It must be borne in mind that the single most serious hazard to surgery in irradiated tissue is the lodgement of bacteria in tissue rendered avascular by the radiation and the secondary necrosis from the infection itself. The basic principles of wound management must be augmented by thorough knowledge of the use of well-vascularized muscle and musculocutaneous flap to provide adequate, blood-rich, soft-tissue coverage.

  7. Determination of thermoluminescence kinetic parameters of terbium-doped zirconium oxide

    NASA Astrophysics Data System (ADS)

    Rivera, T.; Azorín, J.; Falcony, C.; Martínez, E.; García, M.

    2001-06-01

    In recent years considerable importance has been attached to zirconium oxide doped with rare earth (ZrO 2 : RE) thin films due to their desirable characteristics for use in UV dosimetry. In our laboratories we have developed a method to prepare ZrO 2 : RE thin films. Dosimetric characteristics of these materials have been reported previously (Azorin et al., Radiat. Meas. 29 (1998) 315; Radiat. Prot. Dosim. 85 (1999) 317) and results of these have stimulated continued development and analysis of the thermoluminescence mechanism. Two important parameters to be determined in TL studies are the activation energy ( E) and the frequency factor ( s). This paper presents the results of determining kinetic parameters of terbium-doped zirconium oxide (ZrO 2 : Tb) thin films, exposed to 260 nm UV light, using the Lushchik (Sov. Phys. JETF 3 (1956) 390) and Chen (J. Appl. Phys. 40 (1969) 570; J. Electrochem. Soc. 166 (1969) 1254) methods. Kinetic analysis of the glow curve shows second order kinetics for both the first and second glow peaks.

  8. Radiation Emergencies

    MedlinePlus

    ... If the exposure is large enough, it can cause premature aging or even death. Although there are no guarantees of safety during a radiation emergency, you can take actions to protect yourself. You should have a disaster plan. Being prepared can help reduce fear, anxiety ...

  9. Ionizing radiation

    Technology Transfer Automated Retrieval System (TEKTRAN)

    This chapter gives a comprehensive review on ionizing irradiation of fresh fruits and vegetables. Topics include principles of ionizing radiation, its effects on pathogenic and spoilage microorganisms, shelf-life, sensory quality, nutritional and phytochemical composition, as well as physiologic and...

  10. Radiation Models

    ERIC Educational Resources Information Center

    James, W. G. G.

    1970-01-01

    Discusses the historical development of both the wave and the corpuscular photon model of light. Suggests that students should be informed that the two models are complementary and that each model successfully describes a wide range of radiation phenomena. Cites 19 references which might be of interest to physics teachers and students. (LC)

  11. Radiation accidents

    SciTech Connect

    Saenger, E.L.

    1986-09-01

    It is essential that emergency physicians understand ways to manage patients contaminated by radioactive materials and/or exposed to external radiation sources. Contamination accidents require careful surveys to identify the metabolic pathway of the radionuclides to guide prognosis and treatment. The level of treatment required will depend on careful surveys and meticulous decontamination. There is no specific therapy for the acute radiation syndrome. Prophylactic antibodies are desirable. For severely exposed patients treatment is similar to the supportive care given to patients undergoing organ transplantation. For high-dose extremity injury, no methods have been developed to reverse the fibrosing endarteritis that eventually leads to tissue death so frequently found with this type of injury. Although the Three Mile Island episode of March 1979 created tremendous public concern, there were no radiation injuries. The contamination outside the reactor building and the release of radioiodine were negligible. The accidental fuel element meltdown at Chernobyl, USSR, resulted in many cases of acute radiation syndrome. More than 100,000 people were exposed to high levels of radioactive fallout. The general principles outlined here are applicable to accidents of that degree of severity.

  12. Radiation Insulation

    NASA Technical Reports Server (NTRS)

    1987-01-01

    Radiation insulation technology from Apollo and subsequent spacecraft was used to develop superinsulators, used by makers of cold weather apparel, to make parkas, jackets, boots and outdoor gear such as sleeping bags. The radiant barrier technology offers warmth retention at minimal weight and bulk.

  13. Radiation Therapy: Professions in Radiation Therapy

    MedlinePlus

    ... and typically one to two years of clinical physics training. They are certified by the American Board of Radiology or the American Board of Medical Physics . Radiation Therapist Radiation therapists work with radiation oncologists. ...

  14. Risk Factors: Radiation

    Cancer.gov

    Radiation of certain wavelengths, called ionizing radiation, has enough energy to damage DNA and cause cancer. Ionizing radiation includes radon, x-rays, gamma rays, and other forms of high-energy radiation.

  15. Radiation Engineering for Designers

    NASA Technical Reports Server (NTRS)

    Pellish, Jonathan A.

    2015-01-01

    This tutorial provides an overview of the natural space radiation environment, an introduction to radiation effect types, an overview of EEE parts selection, scrubbing, and radiation mitigation, and an introduction to radiation testing.

  16. An Unusual Protector-Protégé Strategy for the Biosynthesis of Purine Nucleoside Antibiotics.

    PubMed

    Wu, Pan; Wan, Dan; Xu, Gudan; Wang, Gui; Ma, Hongmin; Wang, Tingting; Gao, Yaojie; Qi, Jianzhao; Chen, Xiaoxia; Zhu, Jian; Li, Yong-Quan; Deng, Zixin; Chen, Wenqing

    2017-02-16

    Pentostatin (PTN, deoxycoformycin) and arabinofuranosyladenine (Ara-A, vidarabine) are purine nucleoside antibiotics used clinically to treat hematological cancers and human DNA virus infections, respectively. PTN has a 1,3-diazepine ring, and Ara-A is an adenosine analog with an intriguing epimerization at the C-2' hydroxyl group. However, the logic underlying the biosynthesis of these interesting molecules has long remained elusive. Here, we report that the biosynthesis of PTN and Ara-A employs an unusual protector-protégé strategy. To our surprise, we determined that a single gene cluster governs PTN and Ara-A biosynthesis via two independent pathways. Moreover, we verified that PenB functions as a reversible oxidoreductase for the final step of PTN. Remarkably, we provided the first direct biochemical evidence that PTN can protect Ara-A from deamination by selective inhibition of the host adenosine deaminase. These findings expand our knowledge of natural product biosynthesis and open the way for target-directed genome mining of Ara-A/PTN-related antibiotics.

  17. From the research laboratory to the database: the Caenorhabditis elegans kinome in UniProtKB

    PubMed Central

    Magrane, Michele; O'Donovan, Claire

    2017-01-01

    Protein kinases form one of the largest protein families and are found in all species, from viruses to humans. They catalyze the reversible phosphorylation of proteins, often modifying their activity and localization. They are implicated in virtually all cellular processes and are one of the most intensively studied protein families. In recent years, they have become key therapeutic targets in drug development as natural mutations affecting kinase genes are the cause of many diseases. The vast amount of data contained in the primary literature and across a variety of biological data collections highlights the need for a repository where this information is stored in a concise and easily accessible manner. The UniProt Knowledgebase meets this need by providing the scientific community with a comprehensive, high-quality and freely accessible resource of protein sequence and functional information. Here, we describe the expert curation process for kinases, focusing on the Caenorhabditis elegans kinome. The C. elegans kinome is composed of 438 kinases and almost half of them have been functionally characterized, highlighting that C. elegans is a valuable and versatile model organism to understand the role of kinases in biological processes. PMID:28159896

  18. Simulations of the MATROSHKA experiment at the international space station using PHITS.

    PubMed

    Sihver, L; Sato, T; Puchalska, M; Reitz, G

    2010-08-01

    Concerns about the biological effects of space radiation are increasing rapidly due to the perspective of long-duration manned missions, both in relation to the International Space Station (ISS) and to manned interplanetary missions to Moon and Mars in the future. As a preparation for these long-duration space missions, it is important to ensure an excellent capability to evaluate the impact of space radiation on human health, in order to secure the safety of the astronauts/cosmonauts and minimize their risks. It is therefore necessary to measure the radiation load on the personnel both inside and outside the space vehicles and certify that organ- and tissue-equivalent doses can be simulated as accurate as possible. In this paper, simulations are presented using the three-dimensional Monte Carlo Particle and Heavy-Ion Transport code System (PHITS) (Iwase et al. in J Nucl Sci Tech 39(11):1142-1151, 2002) of long-term dose measurements performed with the European Space Agency-supported MATROSHKA (MTR) experiment (Reitz and Berger in Radiat Prot Dosim 120:442-445, 2006). MATROSHKA is an anthropomorphic phantom containing over 6,000 radiation detectors, mimicking a human head and torso. The MTR experiment, led by the German Aerospace Center (DLR), was launched in January 2004 and has measured the absorbed doses from space radiation both inside and outside the ISS. Comparisons of simulations with measurements outside the ISS are presented. The results indicate that PHITS is a suitable tool for estimation of doses received from cosmic radiation and for study of the shielding of spacecraft against cosmic radiation.

  19. Annotation of protein residues based on a literature analysis: cross-validation against UniProtKb

    PubMed Central

    Nagel, Kevin; Jimeno-Yepes, Antonio; Rebholz-Schuhmann, Dietrich

    2009-01-01

    Background A protein annotation database, such as the Universal Protein Resource knowledge base (UniProtKb), is a valuable resource for the validation and interpretation of predicted 3D structure patterns in proteins. Existing studies have focussed on point mutation extraction methods from biomedical literature which can be used to support the time consuming work of manual database curation. However, these methods were limited to point mutation extraction and do not extract features for the annotation of proteins at the residue level. Results This work introduces a system that identifies protein residues in MEDLINE abstracts and annotates them with features extracted from the context written in the surrounding text. MEDLINE abstract texts have been processed to identify protein mentions in combination with taxonomic species and protein residues (F1-measure 0.52). The identified protein-species-residue triplets have been validated and benchmarked against reference data resources (UniProtKb, average F1-measure of 0.54). Then, contextual features were extracted through shallow and deep parsing and the features have been classified into predefined categories (F1-measure ranges from 0.15 to 0.67). Furthermore, the feature sets have been aligned with annotation types in UniProtKb to assess the relevance of the annotations for ongoing curation projects. Altogether, the annotations have been assessed automatically and manually against reference data resources. Conclusion This work proposes a solution for the automatic extraction of functional annotation for protein residues from biomedical articles. The presented approach is an extension to other existing systems in that a wider range of residue entities are considered and that features of residues are extracted as annotations. PMID:19758468

  20. Shortwave Radiation

    NASA Technical Reports Server (NTRS)

    Klassen, Steve; Bugbee, Bruce

    2005-01-01

    Accurate shortwave radiation data is critical to evapotranspiration (ET) models used for developing irrigation schedules to optimize crop production while saving water, minimizing fertilizer, herbicide, and pesticide applications, reducing soil erosion, and protecting surface and ground water quality. Low cost silicon cell pyranometers have proven to be sufficiently accurate and robust for widespread use in agricultural applications under unobstructed daylight conditions. More expensive thermopile pyranometers are required for use as calibration standards and measurements under light with unique spectral properties (electric lights, under vegetation, in greenhouses and growth chambers). Routine cleaning, leveling, and annual calibration checks will help to ensure the integrity of long-term data.

  1. SVM-Prot 2016: A Web-Server for Machine Learning Prediction of Protein Functional Families from Sequence Irrespective of Similarity.

    PubMed

    Li, Ying Hong; Xu, Jing Yu; Tao, Lin; Li, Xiao Feng; Li, Shuang; Zeng, Xian; Chen, Shang Ying; Zhang, Peng; Qin, Chu; Zhang, Cheng; Chen, Zhe; Zhu, Feng; Chen, Yu Zong

    2016-01-01

    Knowledge of protein function is important for biological, medical and therapeutic studies, but many proteins are still unknown in function. There is a need for more improved functional prediction methods. Our SVM-Prot web-server employed a machine learning method for predicting protein functional families from protein sequences irrespective of similarity, which complemented those similarity-based and other methods in predicting diverse classes of proteins including the distantly-related proteins and homologous proteins of different functions. Since its publication in 2003, we made major improvements to SVM-Prot with (1) expanded coverage from 54 to 192 functional families, (2) more diverse protein descriptors protein representation, (3) improved predictive performances due to the use of more enriched training datasets and more variety of protein descriptors, (4) newly integrated BLAST analysis option for assessing proteins in the SVM-Prot predicted functional families that were similar in sequence to a query protein, and (5) newly added batch submission option for supporting the classification of multiple proteins. Moreover, 2 more machine learning approaches, K nearest neighbor and probabilistic neural networks, were added for facilitating collective assessment of protein functions by multiple methods. SVM-Prot can be accessed at http://bidd2.nus.edu.sg/cgi-bin/svmprot/svmprot.cgi.

  2. A stromal cell free culture system generates mouse pro-T cells that can reconstitute T-cell compartments in vivo.

    PubMed

    Gehre, Nadine; Nusser, Anja; von Muenchow, Lilly; Tussiwand, Roxane; Engdahl, Corinne; Capoferri, Giuseppina; Bosco, Nabil; Ceredig, Rhodri; Rolink, Antonius G

    2015-03-01

    T-cell lymphopenia following BM transplantation or diseases such as AIDS result in immunodeficiency. Novel approaches to ameliorate this situation are urgently required. Herein, we describe a novel stromal cell free culture system in which Lineage(-) Sca1(+)c-kit(+) BM hematopoietic progenitors very efficiently differentiate into pro-T cells. This culture system consists of plate-bound Delta-like 4 Notch ligand and the cytokines SCF and IL-7. The pro-T cells developing in these cultures express CD25, CD117, and partially CD44; express cytoplasmic CD3ε; and have their TCRβ locus partially D-J rearranged. They could be expanded for over 3 months and used to reconstitute the T-cell compartments of sublethally irradiated T-cell-deficient CD3ε(-/-) mice or lethally irradiated WT mice. Pro-T cells generated in this system could partially correct the T-cell lymphopenia of pre-Tα(-/-) mice. However, reconstituted CD3ε(-/-) mice suffered from a wasting disease that was prevented by co-injection of purified CD4(+) CD25(high) WT Treg cells. In a T-cell-sufficient or T-lymphopenic setting, the development of disease was not observed. Thus, this in vitro culture system represents a powerful tool to generate large numbers of pro-T cells for transplantation and possibly with clinical applications.

  3. SVM-Prot 2016: A Web-Server for Machine Learning Prediction of Protein Functional Families from Sequence Irrespective of Similarity

    PubMed Central

    Li, Xiao Feng; Li, Shuang; Zeng, Xian; Chen, Shang Ying; Zhang, Peng; Qin, Chu; Zhang, Cheng; Chen, Zhe; Zhu, Feng; Chen, Yu Zong

    2016-01-01

    Knowledge of protein function is important for biological, medical and therapeutic studies, but many proteins are still unknown in function. There is a need for more improved functional prediction methods. Our SVM-Prot web-server employed a machine learning method for predicting protein functional families from protein sequences irrespective of similarity, which complemented those similarity-based and other methods in predicting diverse classes of proteins including the distantly-related proteins and homologous proteins of different functions. Since its publication in 2003, we made major improvements to SVM-Prot with (1) expanded coverage from 54 to 192 functional families, (2) more diverse protein descriptors protein representation, (3) improved predictive performances due to the use of more enriched training datasets and more variety of protein descriptors, (4) newly integrated BLAST analysis option for assessing proteins in the SVM-Prot predicted functional families that were similar in sequence to a query protein, and (5) newly added batch submission option for supporting the classification of multiple proteins. Moreover, 2 more machine learning approaches, K nearest neighbor and probabilistic neural networks, were added for facilitating collective assessment of protein functions by multiple methods. SVM-Prot can be accessed at http://bidd2.nus.edu.sg/cgi-bin/svmprot/svmprot.cgi. PMID:27525735

  4. 13 CFR 126.618 - How does a HUBZone SBC's participation in a Mentor-Protégé relationship affect its participation...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false How does a HUBZone SBC's... Assistance § 126.618 How does a HUBZone SBC's participation in a Mentor-Protégé relationship affect its... HUBZone SBC qualifies as small under part 121 of this chapter, SBA will not find affiliation between...

  5. RADIATION DOSIMETER

    DOEpatents

    Balkwell, W.R. Jr.; Adams, G.D. Jr.

    1960-05-10

    An improvement was made in the determination of amounts of ionizing radiation, particularly low-energy beta particles of less than 1000 rad total dose by means of fluid-phase dosimeter employing a stabilized-- sensitized ferrous-ferric colorimetric system in a sulphuric acid medium. The improvement in the dosimeter consists of adding to the ferrous-ferric system in concentrations of 10/sub -2/ to 10/sup -4/M an organic compound having one or more carboxylic or equivalent groups, such compounds being capable of chelating or complexing the iron ions in the solution. Suitable sensitizing and stabilizing agents are benzoic, phthalic, salicylic, malonic, lactic, maleic, oxalic, citric, succinic, phenolic tartaric, acetic, and adipic acid, as well as other compounds which are added to the solution alone or in certain combinations. As in conventional fluid-phase dosimeters, the absorbed dosage is correlated with a corresponding change in optical density at particular wavelengths of the solution.

  6. Radiation dosimeters

    DOEpatents

    Hoelsher, James W.; Hegland, Joel E.; Braunlich, Peter F.; Tetzlaff, Wolfgang

    1992-01-01

    Radiation dosimeters and dosimeter badges. The dosimeter badges include first and second parts which are connected to join using a securement to produce a sealed area in which at least one dosimeter is held and protected. The badge parts are separated to expose the dosimeters to a stimulating laser beam used to read dose exposure information therefrom. The badge is constructed to allow automated disassembly and reassembly in a uniquely fitting relationship. An electronic memory is included to provide calibration and identification information used during reading of the dosimeter. Dosimeter mounts which reduce thermal heating requirements are shown. Dosimeter constructions and production methods using thin substrates and phosphor binder-layers applied thereto are also taught.

  7. Radiation Insulation

    NASA Technical Reports Server (NTRS)

    1995-01-01

    The Apollo and subsequent spacecraft have had highly effective radiation barriers; made of aluminized polymer film, they bar or let in heat to maintain consistent temperatures inside. Tech 2000, formerly Quantum International Corporation used the NASA technology in its insulating materials, Super "Q" Radiant Barrier, for home, industry and mobile applications. The insulation combines industrial aluminum foil overlaid around a core of another material, usually propylene or mylar. The outer layer reflects up to 97 percent of heat; the central layer creates a thermal break in the structure and thus allows low radiant energy emission. The Quantum Cool Wall, used in cars and trucks, takes up little space while providing superior insulation, thus reducing spoilage and costs. The panels can also dampen sound and engine, exhaust and solar heat.

  8. RADIATION COUNTER

    DOEpatents

    Goldsworthy, W.W.

    1958-02-01

    This patent relates to a radiation counter, and more particularly, to a scintillation counter having high uniform sensitivity over a wide area and capable of measuring alpha, beta, and gamma contamination over wide energy ranges, for use in quickly checking the contami-nation of personnel. Several photomultiplier tubes are disposed in parallel relationship with a light tight housing behind a wall of scintillation material. Mounted within the housing with the photomultipliers are circuit means for producing an audible sound for each pulse detected, and a range selector developing a voltage proportional to the repetition rate of the detected pulses and automatically altering its time constant when the voltage reaches a predetermined value, so that manual range adjustment of associated metering means is not required.

  9. Radiative opacities

    NASA Astrophysics Data System (ADS)

    Seaton, M. J.

    1993-01-01

    An overview of opacity calculations performed during the past decade is presented. Attention is given to envelopes and interiors, equations of state, atomic data, line profiles, and mesh points. Results for a Cepheid model are presented. The solar radiative interior, solar abundances, hydrogen and helium, and contributions from the different elements are discussed. Work over the past decade has led to major revisions in envelope opacities, by factors as large as 3 or 4. There are also some revisions in results for deeper layers, which are important but not so pronounced. A comparison of the work of two opacity research groups, OPAL from the Lawrence Livermore National Laboratory and the international OP project, is given.

  10. Adaptors for radiation detectors

    DOEpatents

    Livesay, Ronald Jason

    2015-07-28

    Described herein are adaptors and other devices for radiation detectors that can be used to make accurate spectral measurements of both small and large bulk sources of radioactivity, such as building structures, soils, vessels, large equipment, and liquid bodies. Some exemplary devices comprise an adaptor for a radiation detector, wherein the adaptor can be configured to collimate radiation passing through the adapter from an external radiation source to the radiation detector and the adaptor can be configured to enclose a radiation source within the adapter to allow the radiation detector to measure radiation emitted from the enclosed radiation source.

  11. Adaptors for radiation detectors

    DOEpatents

    Livesay, Ronald Jason

    2014-04-22

    Described herein are adaptors and other devices for radiation detectors that can be used to make accurate spectral measurements of both small and large bulk sources of radioactivity, such as building structures, soils, vessels, large equipment, and liquid bodies. Some exemplary devices comprise an adaptor for a radiation detector, wherein the adaptor can be configured to collimate radiation passing through the adapter from an external radiation source to the radiation detector and the adaptor can be configured to enclose a radiation source within the adapter to allow the radiation detector to measure radiation emitted from the enclosed radiation source.

  12. Breast radiation - discharge

    MedlinePlus

    Radiation - breast - discharge ... away around 4 to 6 weeks after the radiation treatment is over. You may notice changes in ... breast looks or feels (if you are getting radiation after a lumpectomy). These changes include: Soreness or ...

  13. Radiation Therapy for Cancer

    Cancer.gov

    Radiation therapy is a type of cancer treatment that uses high doses of radiation to kill cancer cells and shrink tumors. Learn about the types of radiation, why side effects happen, which ones you might have, and more.

  14. Foam radiators for transition radiation detectors

    NASA Astrophysics Data System (ADS)

    Chernyatin, V.; Dolgoshein, B.; Gavrilenko, I.; Potekhin, M.; Romaniouk, A.; Sosnovtsev, V.

    1993-02-01

    A wide variety of foam radiators, potentially useful in the design of a transition radiation detector, the possible particle identification tool in collider experiments, have been tested in the beam. Various characteristics of these radiators are compared, and the conclusion is reached that certain brands of polyethylene foam are best suited for use in the detector. Comparison is made with a "traditional" radiator, which is a periodic structure of plastic foils.

  15. Solar radiation resource assessment

    SciTech Connect

    Not Available

    1990-11-01

    The bulletin discusses the following: introduction; Why is solar radiation resource assessment important Understanding the basics; the solar radiation resource assessment project; and future activities.

  16. Identification and characterization of pro-T lymphocytes and lineage- uncommitted lymphocyte precursors from mice with three novel surface markers

    PubMed Central

    1990-01-01

    The study of prethymic stages of T cell development has been limited because specific markers for mouse pro-T lymphocytes were not available. We developed a panel of rat monoclonal antibodies (mAbs) that bind to our pro-T lymphocyte clones obtained from bone marrow of young adult mice and the thymus of 14-d-old embryos. The mAbs, called Joro 30-8, Joro 37-5, and Joro 75, were found to bind to all pro-T clones tested but not to cell lines representing later stages of T cell development, B lymphocyte, or myeloid lineages. We determined the frequency and tissue distribution in normal and immunodeficient mouse strains as well as the ontogeny in liver and thymus of cells positive for these mAbs. The results were consistent with the pattern of reactivity observed with cell lines. We isolated Joro 30-8+, Joro 37- 5+, and Joro 75+ bone marrow cells by cell sorter and found that: (a) phenotypically, they are Thy-1+, CD4-, CD8-, CD3-, B-220-, IgM-, F4/80- , and PgP-1+; (b) they grew in response to the combination of interleukin 3 (IL-3) + IL-4 or IL-3 + IL-4 + IL-6; and (c) Joro 37-5+ and Joro 75+ marrow cells gave rise to mature T lymphocytes but not to B lymphocytes, while Joro 30-8+ marrow cells generated both T and B lymphocytes after 8-12 wk of transfer into severe combined immunodeficient (Scid) mice. In normal mice subjected to 600 rad of irradiation to induce a wave of thymus recolonization, we found by flow fluorocytometry analysis that Joro+ cells entered the thymus 2 d after irradiation, expanded during the next 4 d, and underwent further differentiation, and from day 8 up to day 21, post-irradiation Joro+ cells were no longer detectable in the thymuses. Immunohistochemical analysis of normal thymus shows the presence of very few Joro 30-8+, Joro 37-5+, and Joro 75+ lymphoid cells in the subcapsular area and outer cortex but not in the medulla. The kinetic analysis of tissue sections from thymuses at various days post-irradiation suggests that Joro+ cells enter

  17. Radiation and People

    ERIC Educational Resources Information Center

    Freilich, Florence G.

    1970-01-01

    Describes the development of radiation as a tool of medicine. Includes topics on history of radiation, electromagnetic spectrum, X-ray tubes, high energy machines, radioactive sources, artificial radioactivity, radioactive scanning, units, present radiation background, and effect of radiation on living tissue. (DS)

  18. Radiation transport calculations for cosmic radiation.

    PubMed

    Endo, A; Sato, T

    2012-01-01

    The radiation environment inside and near spacecraft consists of various components of primary radiation in space and secondary radiation produced by the interaction of the primary radiation with the walls and equipment of the spacecraft. Radiation fields inside astronauts are different from those outside them, because of the body's self-shielding as well as the nuclear fragmentation reactions occurring in the human body. Several computer codes have been developed to simulate the physical processes of the coupled transport of protons, high-charge and high-energy nuclei, and the secondary radiation produced in atomic and nuclear collision processes in matter. These computer codes have been used in various space radiation protection applications: shielding design for spacecraft and planetary habitats, simulation of instrument and detector responses, analysis of absorbed doses and quality factors in organs and tissues, and study of biological effects. This paper focuses on the methods and computer codes used for radiation transport calculations on cosmic radiation, and their application to the analysis of radiation fields inside spacecraft, evaluation of organ doses in the human body, and calculation of dose conversion coefficients using the reference phantoms defined in ICRP Publication 110.

  19. Wireless radiation sensor

    DOEpatents

    Lamberti, Vincent E.; Howell, Jr, Layton N.; Mee, David K.; Kress, Reid L.

    2016-08-09

    Disclosed is a sensor for detecting radiation. The sensor includes a ferromagnetic metal and a radiation sensitive material coupled to the ferromagnetic metal. The radiation sensitive material is operable to change a tensile stress of the ferromagnetic metal upon exposure to radiation. The radiation is detected based on changes in the magnetic switching characteristics of the ferromagnetic metal caused by the changes in the tensile stress.

  20. Transgenerational Radiation Epigenetics

    DTIC Science & Technology

    2014-11-01

    human carcinogen to which the military has increased risk of exposure. Radiation causes DNA damage and is a potent mutagen. Radiation also has...Introduction Ionizing radiation is a human carcinogen to which the military has increased risk of exposure (Mettler, 1996). Radiation causes DNA damage...and is a potent mutagen. The dominant paradigm holds that the carcinogenic effects of radiation are due to direct mutagenesis of cancer genes such

  1. Radiation protection guidelines for radiation emergencies

    SciTech Connect

    Lessard, E.T.; Meinhold, C.B.

    1986-01-01

    The system of dose limitation and present guidance for emergency workers and guidance for intervention on behalf of the public are discussed. There are three elements for the system of dose limitation: justification, optimization and dose limits. The first element is basically a political process in this country. Justification is based on a risk-benefit analysis, and justification of the use of radioactive materials or radiation is generally not within the authority of radiation protection managers. Radiation protection managers typically assess detriments or harm caused by radiation exposure and have very little expertise in assessing the benefits of a particular practice involving nuclear material.

  2. Plutonium radiation surrogate

    DOEpatents

    Frank, Michael I.

    2010-02-02

    A self-contained source of gamma-ray and neutron radiation suitable for use as a radiation surrogate for weapons-grade plutonium is described. The source generates a radiation spectrum similar to that of weapons-grade plutonium at 5% energy resolution between 59 and 2614 keV, but contains no special nuclear material and emits little .alpha.-particle radiation. The weapons-grade plutonium radiation surrogate also emits neutrons having fluxes commensurate with the gamma-radiation intensities employed.

  3. Introduction to radiation transport

    SciTech Connect

    Olson, G.L.

    1998-12-31

    This lecture will present time-dependent radiation transport where the radiation is coupled to a static medium, i.e., the material is not in motion. In reality, radiation exerts a pressure on the materials it propagates through and will accelerate the material in the direction of the radiation flow. This fully coupled problem with radiation transport and materials in motion is referred to as radiation-hydrodynamics (or in a shorthand notation: rad-hydro) and is beyond the scope of this lecture.

  4. Radiation protection at synchrotron radiation facilities.

    PubMed

    Liu, J C; Vylet, V

    2001-01-01

    A synchrotron radiation (SR) facility typically consists of an injector, a storage ring, and SR beamlines. The latter two features are unique to SR facilities, when compared to other types of accelerator facilities. The SR facilities have the characteristics of low injection beam power, but high stored beam power. The storage ring is generally above ground with people occupying the experimental floor around a normally thin concrete ring wall. This paper addresses the radiation issues, in particular the shielding design, associated with the storage ring and SR beamlines. Normal and abnormal beam losses for injection and stored beams, as well as typical storage ring operation, are described. Ring shielding design for photons and neutrons from beam losses in the ring is discussed. Radiation safety issues and shielding design for SR beamlines, considering gas bremsstrahlung and synchrotron radiation, are reviewed. Radiation source terms and the methodologies for shielding calculations are presented.

  5. ERLN Radiation Focus Area

    EPA Pesticide Factsheets

    As part of the Environmental Response Laboratory Network, the National Air and Radiation Environmental Laboratory (NAREL) here provides your laboratory with access to radiation-specific laboratory guidance documents and training courses.

  6. What Is Radiation Shielding?

    NASA Video Gallery

    Kerry Lee, NASA Orion radiation system manager, explains how radiation shielding is used to block harmful particles coming into the spacecraft without producing secondary particles that can cause e...

  7. Radiation Oncology Treatment Team

    MedlinePlus

    ... patients to be advocates. View more information Treatment Team Quick Links Meet the Treatment Team Radiation Oncologist ... as medical oncologists and surgeons to maximize radiation’s effectiveness. Radiation oncologists are the only physicians with the ...

  8. Cell Radiation Experiment System

    NASA Technical Reports Server (NTRS)

    Morrison, Dennis R.

    2010-01-01

    The cell radiation experiment system (CRES) is a perfused-cell culture apparatus, within which cells from humans or other animals can (1) be maintained in homeostasis while (2) being exposed to ionizing radiation during controlled intervals and (3) being monitored to determine the effects of radiation and the repair of radiation damage. The CRES can be used, for example, to determine effects of drug, radiation, and combined drug and radiation treatments on both normal and tumor cells. The CRES can also be used to analyze the effects of radiosensitive or radioprotectant drugs on cells subjected to radiation. The knowledge gained by use of the CRES is expected to contribute to the development of better cancer treatments and of better protection for astronauts, medical-equipment operators, and nuclear-power-plant workers, and others exposed frequently to ionizing radiation.

  9. Space Radiation Program Element

    NASA Technical Reports Server (NTRS)

    Krenek, Sam

    2008-01-01

    This poster presentation shows the various elements of the Space Radiation Program. It reviews the program requirements: develop and validate standards, quantify space radiation human health risks, mitigate risks through countermeasures and technologies, and treat and monitor unmitigated risks.

  10. Radiation Protection Handbook

    NASA Technical Reports Server (NTRS)

    1972-01-01

    A handbook which sets forth the Kennedy Space Center radiation protection policy is presented. The book also covers administrative direction and guidance on organizational and procedural requirements of the program. Only ionizing radiation is covered.

  11. Radiation Protection in Canada

    PubMed Central

    Williams, N.

    1965-01-01

    The main emphasis of a provincial radiation protection program is on ionizing radiation produced by machines, although assistance is given to the Federal Radiation Protection Division in its program relating to radioactive substances. The basis for the Saskatchewan program of radiation protection is the Radiological Health Act 1961. An important provision of the Act is annual registration of radiation equipment. The design of the registration form encourages a “do-it-yourself” radiation and electrical safety inspection. Installations are inspected every two years by a radiation health officer. Two hundred and twenty-one deficiencies were found during inspection of 224 items of radiation equipment, the commonest being failure to use personal film badges. Insufficient filtration of the beam, inadequate limitation of the beam, and unnecessary exposure of operators were other common faults. Physicians have a responsibility to weigh the potential advantages against the hazards when requesting radiographic or fluoroscopic procedures. PMID:14282164

  12. Radiation from hard objects

    SciTech Connect

    Canavan, G.H.

    1997-02-01

    The inference of the diameter of hard objects is insensitive to radiation efficiency. Deductions of radiation efficiency from observations are very sensitive - possibly overly so. Inferences of the initial velocity and trajectory vary similarly, and hence are comparably sensitive.

  13. Prostate Cancer (Radiation Therapy)

    MedlinePlus

    ... to three years. If I choose surgery, will radiation treatment still be required? If your surgery is ... option with your physician team. If I choose radiation therapy, will surgical treatment still be an option? ...

  14. Radiation effects in space

    SciTech Connect

    Fry, R.J.M.

    1986-01-01

    The paper discusses the radiation environment in space that astronauts are likely to be exposed to. Emphasis is on proton and HZE particle effects. Recommendations for radiation protection guidelines are presented. (ACR)

  15. Fluorescent radiation converter

    NASA Technical Reports Server (NTRS)

    Viehmann, W. (Inventor)

    1981-01-01

    A fluorescence radiation converter is described which includes a substantially undoped optically transparent substrate and a waveshifter coating deposited on at least one portion of the substrate for absorption of radiation and conversion of fluorescent radiation. The coating is formed to substantially 1000 g/liter of a solvent, 70 to 200 g/liter of an organic polymer, and 0.2 to 25 g/liter of at least one organic fluorescent dye. The incoming incident radiation impinges on the coating. Radiation is absorbed by the fluorescent dye and is re-emitted as a longer wavelength radiation. Radiation is trapped within the substrate and is totally internally reflected by the boundary surface. Emitted radiation leaves the substrate ends to be detected.

  16. Hybrid radiator cooling system

    SciTech Connect

    France, David M.; Smith, David S.; Yu, Wenhua; Routbort, Jules L.

    2016-03-15

    A method and hybrid radiator-cooling apparatus for implementing enhanced radiator-cooling are provided. The hybrid radiator-cooling apparatus includes an air-side finned surface for air cooling; an elongated vertically extending surface extending outwardly from the air-side finned surface on a downstream air-side of the hybrid radiator; and a water supply for selectively providing evaporative cooling with water flow by gravity on the elongated vertically extending surface.

  17. External radiation surveillance

    SciTech Connect

    Antonio, E.J.

    1995-06-01

    This section of the 1994 Hanford Site Environmental Report describes how external radiation was measured, how surveys were performed, and the results of these measurements and surveys. External radiation exposure rates were measured at locations on and off the Hanford Site using thermoluminescent dosimeters (TLD). External radiation and contamination surveys were also performed with portable radiation survey instruments at locations on and around the Hanford Site.

  18. (Mis)Understanding Radiation

    SciTech Connect

    Schreiber, Stephen Bruce

    2016-02-10

    This set of slides discusses radiation and fears concerning it at a non-technical level. Included are some misconceptions and practical consequences resulting from these. The concept of radiation hormesis is explained. The author concludes that a number of significant societal benefits are being foregone because of overly cautious concerns about low-level radiation.

  19. Spacecraft radiator systems

    NASA Technical Reports Server (NTRS)

    Anderson, Grant A. (Inventor)

    2012-01-01

    A spacecraft radiator system designed to provide structural support to the spacecraft. Structural support is provided by the geometric "crescent" form of the panels of the spacecraft radiator. This integration of radiator and structural support provides spacecraft with a semi-monocoque design.

  20. Radiation port dermatophytosis

    SciTech Connect

    Rosen, T.; Dupuy, J.; Maor, M.; Altman, A.

    1988-12-01

    We report two cases in which dermatophytic infection developed almost entirely within a radiation field mimicking an acute radiation effect. Radiotherapists and dermatologists should be aware of this possibility and be able to differentiate it from radiation dermatitis. Topical antifungal agents are the recommended treatment after diagnosis is established.

  1. Ionizing Radiation: The issue of radiation quality

    NASA Astrophysics Data System (ADS)

    Prise, Kevin; Schettino, Giuseppe

    Types of Ionising radiations are differentiated from each other by fundamental characteristics of their energy deposition patterns when they interact with biological materials. At the level of the DNA these non-random patterns drive differences in the yields and distributions of DNA damage patterns and specifically the production of clustered damage or complex lesions. The complex radiation fields found in space bring significant challenges for developing a mechanistic understanding of radiation effects from the perspective of radiation quality as these consist of a diverse range of particle and energy types unique to the space environment. Linear energy transfer, energy deposited per unit track length in units of keV per micron, has long been used as a comparator for different types of radiation but has limitations in that it is an average value. Difference in primary core ionizations relative to secondary delta ray ranges vary significantly with particle mass and energy leading to complex interrelationships with damage production at the cellular level. At the cellular level a greater mechanistic understanding is necessary, linking energy deposition patterns to DNA damage patterns and cellular response, to build appropriate biophysical models that are predictive for different radiation qualities and mixed field exposures. Defined studies using monoenergetic beams delivered under controlled conditions are building quantitative data sets of both initial and long term changes in cells as a basis for a great mechanistic understanding of radiation quality effects of relevance to not only space exposures but clinical application of ion-beams.

  2. Radiation Therapy: Additional Treatment Options

    MedlinePlus

    ... Upper GI What is Radiation Therapy? Find a Radiation Oncologist Last Name: Facility: City: State: Zip Code: ... infections. This is refered to as immunotherapy . Intraoperative Radiation Therapy Radiation therapy given during surgery is called ...

  3. RADIATION WAVE DETECTOR

    DOEpatents

    Wouters, L.F.

    1958-10-28

    The detection of the shape and amplitude of a radiation wave is discussed, particularly an apparatus for automatically indicating at spaced lntervals of time the radiation intensity at a flxed point as a measure of a radiation wave passing the point. The apparatus utilizes a number of photomultiplier tubes surrounding a scintillation type detector, For obtainlng time spaced signals proportional to radiation at predetermined intervals the photolnultiplier tubes are actuated ln sequence following detector incidence of a predetermined radiation level by electronic means. The time spaced signals so produced are then separately amplified and relayed to recording means.

  4. Radiation detection system

    DOEpatents

    Nelson, Melvin A.; Davies, Terence J.; Morton, III, John R.

    1976-01-01

    A radiation detection system which utilizes the generation of Cerenkov light in and the transmission of that light longitudinally through fiber optic wave guides in order to transmit intelligence relating to the radiation to a remote location. The wave guides are aligned with respect to charged particle radiation so that the Cerenkov light, which is generated at an angle to the radiation, is accepted by the fiber for transmission therethrough. The Cerenkov radiation is detected, recorded, and analyzed at the other end of the fiber.

  5. Solar cell radiation handbook

    NASA Technical Reports Server (NTRS)

    Carter, J. R., Jr.; Tada, H. Y.

    1973-01-01

    A method is presented for predicting the degradation of a solar array in a space radiation environment. Solar cell technology which emphasizes the cell parameters that degrade in a radiation environment, is discussed along with the experimental techniques used in the evaluation of radiation effects. Other topics discussed include: theoretical aspects of radiation damage, methods for developing relative damage coefficients, nature of the space radiation environment, method of calculating equivalent fluence from electron and proton energy spectrums and relative damage coefficients, and comparison of flight data with estimated degradation.

  6. PERSONAL RADIATION MONITOR

    DOEpatents

    Dilworth, R.H.; Borkowski, C.J.

    1961-12-26

    A transistorized, fountain pen type radiation monitor to be worn on the person is described. Radiation produces both light flashes in a small bulb and an audible warning tone, the frequency of both the tone and light flashes being proportional to radiation intensity. The device is powered by a battery and a blocking oscillator step-up power supply The oscillator frequency- is regulated to be proportional to the radiation intensity, to provide adequate power in high radiation fields, yet minimize battery drain at low operating intensities. (AEC)

  7. Radiation protection in space

    SciTech Connect

    Blakely, E.A.; Fry, R.J.M.

    1995-02-01

    The challenge for planning radiation protection in space is to estimate the risk of events of low probability after low levels of irradiation. This work has revealed many gaps in the present state of knowledge that require further study. Despite investigations of several irradiated populations, the atomic-bomb survivors remain the primary basis for estimating the risk of ionizing radiation. Compared to previous estimates, two new independent evaluations of available information indicate a significantly greater risk of stochastic effects of radiation (cancer and genetic effects) by about a factor of three for radiation workers. This paper presents a brief historical perspective of the international effort to assure radiation protection in space.

  8. Solar radiation measurement project

    NASA Technical Reports Server (NTRS)

    Ioup, J. W.

    1981-01-01

    The Xavier solar radiation measurement project and station are described. Measurements of the total solar radiation on a horizontal surface from an Eppley pyranometer were collected into computer data files. Total radiation in watt hours was converted from ten minute intervals to hourly intervals. Graphs of this total radiation data are included. A computer program in Fortran was written to calculate the total extraterrestrial radiation on a horizontal surface for each day of the month. Educational and social benefits of the project are cited.

  9. Radiation-induced gliomas

    PubMed Central

    Prasad, Gautam; Haas-Kogan, Daphne A.

    2013-01-01

    Radiation-induced gliomas represent a relatively rare but well-characterized entity in the neuro-oncologic literature. Extensive retrospective cohort data in pediatric populations after therapeutic intracranial radiation show a clearly increased risk in glioma incidence that is both patient age- and radiation dose/volume-dependent. Data in adults are more limited but show heightened risk in certain groups exposed to radiation. In both populations, there is no evidence linking increased risk associated with routine exposure to diagnostic radiation. At the molecular level, recent studies have found distinct genetic differences between radiation-induced gliomas and their spontaneously-occurring counterparts. Clinically, there is understandable reluctance on the part of clinicians to re-treat patients due to concern for cumulative neurotoxicity. However, available data suggest that aggressive intervention can lead to improved outcomes in patients with radiation-induced gliomas. PMID:19831840

  10. Americans' Average Radiation Exposure

    SciTech Connect

    NA

    2000-08-11

    We live with radiation every day. We receive radiation exposures from cosmic rays, from outer space, from radon gas, and from other naturally radioactive elements in the earth. This is called natural background radiation. It includes the radiation we get from plants, animals, and from our own bodies. We also are exposed to man-made sources of radiation, including medical and dental treatments, television sets and emission from coal-fired power plants. Generally, radiation exposures from man-made sources are only a fraction of those received from natural sources. One exception is high exposures used by doctors to treat cancer patients. Each year in the United States, the average dose to people from natural and man-made radiation sources is about 360 millirem. A millirem is an extremely tiny amount of energy absorbed by tissues in the body.

  11. RF radiation from lightning

    NASA Technical Reports Server (NTRS)

    Levine, D. M.

    1978-01-01

    Radiation from lightning in the RF band from 3-300 MHz were monitored. Radiation in this frequency range is of interest as a potential vehicle for monitoring severe storms and for studying the lightning itself. Simultaneous measurements were made of RF radiation and fast and slow field changes. Continuous analogue recordings with a system having 300 kHz of bandwidth were made together with digital records of selected events (principally return strokes) at greater temporal resolution. The data reveal patterns in the RF radiation for the entire flash which are characteristic of flash type and independent of the frequency of observation. Individual events within the flash also have characteristic RF patterns. Strong radiation occurs during the first return strokes, but delayed about 20 micron sec with respect to the begining of the return stroke; whereas, RF radiation from subsequent return strokes tends to be associated with cloud processes preceding the flash with comparatively little radiation occurring during the return stroke itself.

  12. Radiation curing of epoxies

    NASA Astrophysics Data System (ADS)

    Dickson, Lawrence W.; Singh, Ajit

    The literature on radiation polymerization of epoxy compounds has been reviewed to assess the potential use of radiation for curing these industrially important monomers. Chemical curing of epoxies may proceed by either cationic or anionic mechanisms depending on the nature of the curing agent, but most epoxies polymerize by cationic mechanisms under the influence of high-energy radiation. Radiation-induced cationic polymerization of epoxy compounds is inhibited by trace quantities of water because of proton transfer from the chain-propagating epoxy cation to water. Several different methods with potential for obtaining high molecular weight polymers by curing epoxies with high-energy radiation have been studied. Polymeric products with epoxy-like properties have been produced by radiation curing of epoxy oligomers with terminal acrylate groups and mixtures of epoxies with vinyl monomers. Both of these types of resin have good potential for industrial-scale curing by radiation treatment.

  13. COHERENCE PROPERTIES OF ELECTROMAGNETIC RADIATION,

    DTIC Science & Technology

    ELECTROMAGNETIC RADIATION , COHERENT SCATTERING), (*COHERENT SCATTERING, ELECTROMAGNETIC RADIATION ), LIGHT, INTERFERENCE, INTENSITY, STATISTICAL FUNCTIONS, QUANTUM THEORY, BOSONS, INTERFEROMETERS, CHINA

  14. Radiation Therapy: Professions in Radiation Therapy

    MedlinePlus

    ... the equipment works properly. They also take precise measurements of radiation beam characteristics and do other safety ... accredited facilities database . This website does not provide cost information. The costs for specific medical imaging tests, ...

  15. Acute radiation syndrome and chronic radiation syndrome.

    PubMed

    Grammaticos, Philip; Giannoula, Evanthia; Fountos, George P

    2013-01-01

    Acute radiation syndrome (ARS) or sickness or poisoning or toxicity is induced after a whole body exposure of men to high doses of radiation between 1-12Gy. First symptoms are from the gastrointestinal system, which together with bone marrow are the most sensitive parts of our body. Chronic radiation syndrome (CRS) may be induced by smaller than 1Gy radiation doses or after a mild form of ARS. Prophylaxis and treatment suggestions are described. In cases of ARS, a large part of the exposed population after proper medical care may survive, while without medical care this part of the population will be lost. Prophylaxis may also save another part of the population.

  16. The Radiation Transport Conundrum in Radiation Hydrodynamics

    SciTech Connect

    Castor, J I

    2005-03-18

    The summary of this paper is: (1) The conundrum in the title is whether to treat radiation in the lab frame or the comoving frame in a radiation-hydrodynamic problem; (2) Several of the difficulties are associated with combining a somewhat relativistic treatment of radiation with a non-relativistic treatment of hydrodynamics; (3) The principal problem is a tradeoff between easily obtaining the correct diffusion limit and describing free-streaming radiation with the correct wave speed; (4) The computational problems of the comoving-frame formulation in more than one dimension, and the difficulty of obtaining both exact conservation and full u/c accuracy argue against this method; (5) As the interest in multi-D increases, as well as the power of computers, the lab-frame method is becoming more attractive; and (6) The Monte Carlo method combines the advantages of both lab-frame and comoving-frame approaches, its only disadvantage being cost.

  17. High-power radiating plasma

    NASA Technical Reports Server (NTRS)

    Rozanov, V. B.; Rukhadze, A. A.

    1984-01-01

    The physical principles underlying the use of radiating plasmas for the optical pumping of lasers are described. Particular consideration is given to the properties of radiating plasmas; radiation selectivity; the dynamics, equilibrium, and stability of radiating plasmas; the radiative Reynolds number; and experimental results on radiating discharges.

  18. Thermal radiation measuring arrangement

    SciTech Connect

    Berman, H.L.; Sprout, J.C.

    1983-02-08

    In a thermal radiation measuring arrangement, a thermal radiation detector is located at the focal point of a collecting mirror, upon which incident thermal radiation from a surface, such as a building wall, is directed. The thermal radiation detector may be, for example, a thermopile, and provides an output signal having a magnitude proportional to the amount of thermal radiation which it receives. The temperature detection means detects the temperature of the thermal radiation detector and, for example, may detect the cold junction of the thermopile. In a first operating condition, a signal summing means receives the output signal from the thermal radiation detector and the temperature detection means and provides a third output signal proportional to the sum of these first and second output signals. In a second operating condition, a signal biasing means is connected into the signal summing means. The signal biasing means provides a signal to the signal summing means to cause the third output signal to become zero when radiation is received from a reference surface. When the arrangement is in the second operating condition and directed to receive thermal radiation from a second surface different from the reference surface, the signal biasing means maintains the same level of bias to the signal summing means as it did when detecting the radiation from the reference surface.

  19. Complications of radiation therapy

    SciTech Connect

    Dalinka, M.K.; Mazzeo, V.P. Jr.

    1985-01-01

    The skeletal effects of radiation are dependent upon many variables, but the pathologic features are consistent. Radiation may cause immediate or delayed cell death, cellular injury with recovery, arrest of cellular division, or abnormal repair with neoplasia. Radiation necrosis and radiation-induced neoplasm still occur despite the use of supervoltage therapy. Complications of radiotherapy are well known and have led to more judicious use of this therapeutic modality. With few exceptions, benign bone tumors are no longer treated with irradiation. Radiation necrosis may be difficult to differentiate from sarcoma arising in irradiated bone. They both occur within the field of irradiation. Radiation necrosis often has a long latent period which is, of course, the rule in radiation-induced neoplasia. A soft tissue mass favors the diagnosis of neoplasia, while its absence suggests radiation necrosis. Lack of pain favors necrosis. Calcification may occur in radiation necrosis and does not indicate neoplasia. A lack of progression on serial roentgenograms also favors radiation necrosis. 76 references.

  20. Radiation physics, biophysics, and radiation biology

    SciTech Connect

    Hall, E.J.; Zaider, M.

    1993-05-01

    Research at the Center for Radiological Research is a multidisciplenary blend of physics, chemistry and biology aimed at understanding the mechanisms involved in the health problems resulting from human exposure to ionizing radiations. The focus is increased on biochemistry and the application of the techniques of molecular biology to the problems of radiation biology. Research highlights of the program from the past year are described. A mathematical model describing the production of single-strand and double-strand breaks in DNA as a function radiation quality has been completed. For the first time Monte Carlo techniques have been used to obtain directly the spatial distribution of DNA moieties altered by radiation. This information was obtained by including the transport codes a realistic description of the electronic structure of DNA. We have investigated structure activity relationships for the potential oncogenicity of a new generation of bioreductive drugs that function as hypoxic cytotoxins. Experimental and theoretical investigation of the inverse dose rate effect, whereby medium LET radiations actually produce an c effect when the dose is protracted, is now at a point where the basic mechanisms are reasonably understood and the complex interplay between dose, dose rate and radiation quality which is necessary for the effect to be present can now be predicted at least in vitro. In terms of early radiobiological damage, a quantitative link has been established between basic energy deposition and locally multiply damaged sites, the radiochemical precursor of DNA double strand breaks; specifically, the spatial and energy deposition requirements necessary to form LMDs have been evaluated. For the first time, a mechanically understood biological fingerprint'' of high-LET radiation has been established. Specifically measurement of the ratio of inter-to intra-chromosomal aberrations produces a unique signature from alpha-particles or neutrons.

  1. Understanding how and why the Gene Ontology and its annotations evolve: the GO within UniProt.

    PubMed

    Huntley, Rachael P; Sawford, Tony; Martin, Maria J; O'Donovan, Claire

    2014-03-18

    The Gene Ontology Consortium (GOC) is a major bioinformatics project that provides structured controlled vocabularies to classify gene product function and location. GOC members create annotations to gene products using the Gene Ontology (GO) vocabularies, thus providing an extensive, publicly available resource. The GO and its annotations to gene products are now an integral part of functional analysis, and statistical tests using GO data are becoming routine for researchers to include when publishing functional information. While many helpful articles about the GOC are available, there are certain updates to the ontology and annotation sets that sometimes go unobserved. Here we describe some of the ways in which GO can change that should be carefully considered by all users of GO as they may have a significant impact on the resulting gene product annotations, and therefore the functional description of the gene product, or the interpretation of analyses performed on GO datasets. GO annotations for gene products change for many reasons, and while these changes generally improve the accuracy of the representation of the underlying biology, they do not necessarily imply that previous annotations were incorrect. We additionally describe the quality assurance mechanisms we employ to improve the accuracy of annotations, which necessarily changes the composition of the annotation sets we provide. We use the Universal Protein Resource (UniProt) for illustrative purposes of how the GO Consortium, as a whole, manages these changes.

  2. Revealing Both Sides of the Story: A Comparative Analysis of Mentors and Protégés Relational Perspectives.

    PubMed

    Varga, Shannon M; Deutsch, Nancy L

    2016-10-01

    Mentoring continues to be a popular intervention for promoting positive youth development. However, the underlying mechanisms associated with sustainable and successful relationships remain largely unknown. Our study aimed to expand on previous literature by examining characteristics that have previously been linked to mentoring outcomes (e.g., authenticity, empathy), from a process-focused lens. We utilized post program satisfaction scores and interviews to examine the presence of each characteristic in a large sample of dyads (n = 144) as well as dyads' levels of agreement or disagreement about aspects of the relationships. We found that high satisfaction dyads demonstrated greater congruity and detail in their descriptions of their relationships, whereas low satisfaction dyads were highly divergent and inconsistent in their descriptions. In addition, misattunement, a negative relational aspect, was the most powerful distinguisher between high and low satisfaction dyads, which provides support for mentors receiving attunement training in order to reduce instances of misattunement. Findings from this study highlight the importance of examining and assessing mentoring relationships from both the mentor and protégé perspectives, as a single perspective may not present a full picture of the relationship.

  3. Radiation exposure and pregnancy.

    PubMed

    Labant, Amy; Silva, Christina

    2014-01-01

    Radiological exposure from nuclear power reactor accidents, transportation of nuclear waste accidents, industrial accidents, or terrorist activity may be a remote possibility, but it could happen. Nurses must be prepared to evaluate and treat pregnant women and infants who have been exposed to radiation, and to have an understanding of the health consequences of a nuclear or radiological incident. Pregnant women and infants are a special group of patients who need consideration when exposed to radiation. Initial care requires thorough assessment and decisions regarding immediate care needs. Ongoing care is based on type and extent of radiation exposure. With accurate, comprehensive information and education, nurses will be better prepared to help mitigate the effects of radiation exposure to pregnant women and infants following a radiological incident. Information about radiation, health effects of prenatal radiation exposure, assessment, patient care, and treatment of pregnant women and infants are presented.

  4. RADIATION WAVE DETECTION

    DOEpatents

    Wouters, L.F.

    1960-08-30

    Radiation waves can be detected by simultaneously measuring radiation- wave intensities at a plurality of space-distributed points and producing therefrom a plot of the wave intensity as a function of time. To this end. a detector system is provided which includes a plurality of nuclear radiation intensity detectors spaced at equal radial increments of distance from a source of nuclear radiation. Means are provided to simultaneously sensitize the detectors at the instant a wave of radiation traverses their positions. the detectors producing electrical pulses indicative of wave intensity. The system further includes means for delaying the pulses from the detectors by amounts proportional to the distance of the detectors from the source to provide an indication of radiation-wave intensity as a function of time.

  5. Earth Radiation Measurement Science

    NASA Technical Reports Server (NTRS)

    Smith, G. Louis

    2000-01-01

    This document is the final report for NASA Grant NAG1-1959, 'Earth Radiation Measurement Science'. The purpose of this grant was to perform research in this area for the needs of the Clouds and Earth Radiant Energy System (CERES) project and for the Earth Radiation Budget Experiment (ERBE), which are bing conducted by the Radiation and Aerosols Branch of the Atmospheric Sciences Division of Langley Research Center. Earth Radiation Measurement Science investigates the processes by which measurements are converted into data products. Under this grant, research was to be conducted for five tasks: (1) Point Response Function Measurements; (2) Temporal Sampling of Outgoing Longwave Radiation; (3) Spatial Averaging of Radiation Budget Data; (4) CERES Data Validation and Applications; and (5) ScaRaB Data Validation and Application.

  6. Radiation | Smokefree.gov

    Cancer.gov

    About half of all cancer patients get radiation therapy. This treatment can damage healthy cells, which can cause uncomfortable side effects. Use this action deck to get information on common symptoms that affect people going through radiation and learn how to manage them. The side effects of radiation may depend on the part of your body being treated. If you don’t see the symptom cards that describe what you are going through, try building your own deck.

  7. Prostaglandins and Radiation Enteritis

    DTIC Science & Technology

    1987-12-30

    acid deficient diet did provide significant survival advantage following abdominal radiation. Abdominal radiation did not result in outpouring of fluid...mortality for rats given quinacrine .......... 31 19 PGE excretion for fatty acid deficient rats .......... 35 20 Leukocyte counts for fatty acid ...deficient rats ..... 35 21 Mucosa height for fatty acid deficient rats .......... 36 22 Leukocyte counts for rats prior to radiation ......... 37 23 Mean

  8. RHOBOT: Radiation hardened robotics

    SciTech Connect

    Bennett, P.C.; Posey, L.D.

    1997-10-01

    A survey of robotic applications in radioactive environments has been conducted, and analysis of robotic system components and their response to the varying types and strengths of radiation has been completed. Two specific robotic systems for accident recovery and nuclear fuel movement have been analyzed in detail for radiation hardness. Finally, a general design approach for radiation-hardened robotics systems has been developed and is presented. This report completes this project which was funded under the Laboratory Directed Research and Development program.

  9. Aerosol, radiation, and climate

    NASA Technical Reports Server (NTRS)

    Pollack, J. B.

    1983-01-01

    Airborne, spaceborne, and ground-based measurements are used to study the radiative and climatic effects of aerosols. The data, which are modelled with a hierarchy of radiation and climate models, and their implications are summarized. Consideration is given to volcanic aerosols, polar stratospheric clouds, and the Arctic haze. It is shown that several types of aerosols (volcanic particles and the Arctic haze) cause significant alterations to the radiation budget of the regions where they are located.

  10. Radiation Countermeasures Symposium: Introduction

    DTIC Science & Technology

    2011-06-15

    SH-containing molecules) protected animals from acute radiation syndrome (ARS). Free radical scavengers • 1950s-1980s: US Army (WRAIR) advanced...applications for G-CSF (Neupogen®) in case of radiation incident • Neupogen® in Strategic National Stockpile UNI FORM ED SERVIC ESUNIV ERSI T Y of theHealth...success for any radiation countermeasure under Animal Rule: long-term survival? (Need to cure hematopoietic syndrome when assessing GI

  11. Intracranial interstitial radiation

    SciTech Connect

    Willis, D.; Rittenmeyer, H.; Hitchon, P.

    1986-06-01

    Primary malignant brain tumors are fatal, with 90% of patients having these tumors dying within two years following diagnosis. Cranial interstitial radiation therapy, a technique under investigation to control these tumors, involves implantation of radioactive iodine 125 seeds into the tumor bed by stereotaxic technique. The interstitial radiation technique, monitoring of radiation, and nursing care of patients are discussed. Case histories are presented, along with discussion of results attained using this therapy, and its future.

  12. Radiation budget study

    NASA Astrophysics Data System (ADS)

    Hartmann, D. L.

    Scientific applications of satellite measurements of the radiative flux density at the top of the atmosphere are discussed in a general review and illustrated with diagrams, maps, and graphs. Topics examined include model development and verification, empirical studies of the global radiation budget, regional energy budgeting, interannual-variability studies, and seasonal and nonseasonal variations in ocean-land radiation budgets. The need for long-term homogeneous series of observations with good spatial and temporal resolution is stressed.

  13. Electromagnetic Radiation Analysis

    DTIC Science & Technology

    1978-04-10

    A methodology is given for determining whether electromagnetic radiation of sufficient strength to cause performance degradation to the test item...exists at the test item location. The results of an electromagnetic radiation effects test are used to identify the radio frequencies and electromagnetic ... radiation levels to which the test item is susceptible. Further, using a test bed, comparisons are made with the representative signal levels to

  14. Radiation coloration resistant glass

    DOEpatents

    Tomozawa, M.; Watson, E.B.; Acocella, J.

    1986-11-04

    A radiation coloration resistant glass is disclosed which is used in a radiation environment sufficient to cause coloration in most forms of glass. The coloration resistant glass includes higher proportions by weight of water and has been found to be extremely resistant to color change when exposed to such radiation levels. The coloration resistant glass is free of cerium oxide and has more than about 0.5% by weight water content. Even when exposed to gamma radiation of more than 10[sup 7] rad, the coloration resistant glass does not lose transparency. 3 figs.

  15. Radiation coloration resistant glass

    DOEpatents

    Tomozawa, Minoru; Watson, E. Bruce; Acocella, John

    1986-01-01

    A radiation coloration resistant glass is disclosed which is used in a radiation environment sufficient to cause coloration in most forms of glass. The coloration resistant glass includes higher proportions by weight of water and has been found to be extremely resistant to color change when exposed to such radiation levels. The coloration resistant glass is free of cerium oxide and has more than about 0.5% by weight water content. Even when exposed to gamma radiation of more than 10.sup.7 rad, the coloration resistant glass does not lose transparency.

  16. [Thyroid and radiation].

    PubMed

    Yamashita, S; Namba, H; Nagataki, S

    1993-11-20

    The topic "Thyroid and Radiation" is both an old and a new area to be solved by human beings. The thyroid is an organ that is usually susceptible to exposure to ionizing radiation, both by virtue of its ability to concentrate radioiodine (internal radiation) and by routine medical examination: Chest X-ray, Dental X-ray, X-irradiation of cervical lymphnodes etc. (external radiation). Iodine-131 is widely used for the therapy of Graves' disease and thyroid cancers, of which the disadvantage is radiation-induced hypothyroidism but not complications of thyroid tumor. The thyroid gland is comparatively radioresistant, however, the data obtained from Hiroshima, Nagasaki and Marshall islands indicates a high incidence of external radiation-induced thyroid tumors as well as hypothyroidism. The different biological effects of internal and external radiation remains to be further clarified. Interestingly, recent reports demonstrate the increased number of thyroid cancer in children around Chernobyl in Belarus. In this review, we would like to introduce the effect of radiation on the thyroid gland at the molecular, cellular and tissue levels. Furthermore the clinical usefulness of iodine-131, including the safety-control for radiation exposure will be discussed.

  17. Rotating bubble membrane radiator

    DOEpatents

    Webb, Brent J.; Coomes, Edmund P.

    1988-12-06

    A heat radiator useful for expelling waste heat from a power generating system aboard a space vehicle is disclosed. Liquid to be cooled is passed to the interior of a rotating bubble membrane radiator, where it is sprayed into the interior of the bubble. Liquid impacting upon the interior surface of the bubble is cooled and the heat radiated from the outer surface of the membrane. Cooled liquid is collected by the action of centrifical force about the equator of the rotating membrane and returned to the power system. Details regarding a complete space power system employing the radiator are given.

  18. Flexible radiator system

    NASA Technical Reports Server (NTRS)

    Oren, J. A.

    1982-01-01

    The soft tube radiator subsystem is described including applicable system requirements, the design and limitations of the subsystem components, and the panel manufacturing method. The soft tube radiator subsystem is applicable to payloads requiring 1 to 12 kW of heat rejection for orbital lifetimes per mission of 30 days or less. The flexible radiator stowage volume required is about 60% and the system weight is about 40% of an equivalent heat rejection rigid panel. The cost should also be considerably less. The flexible radiator is particularly suited to shuttle orbiter sortie payloads and also whose mission lengths do not exceed the 30 day design life.

  19. Potential theory of radiation

    NASA Technical Reports Server (NTRS)

    Chiu, Huei-Huang

    1989-01-01

    A theoretical method is being developed by which the structure of a radiation field can be predicted by a radiation potential theory, similar to a classical potential theory. The introduction of a scalar potential is justified on the grounds that the spectral intensity vector is irrotational. The vector is also solenoidal in the limits of a radiation field in complete radiative equilibrium or in a vacuum. This method provides an exact, elliptic type equation that will upgrade the accuracy and the efficiency of the current CFD programs required for the prediction of radiation and flow fields. A number of interesting results emerge from the present study. First, a steady state radiation field exhibits an optically modulated inverse square law distribution character. Secondly, the unsteady radiation field is structured with two conjugate scalar potentials. Each is governed by a Klein-Gordon equation with a frictional force and a restoring force. This steady potential field structure and the propagation of radiation potentials are consistent with the well known results of classical electromagnetic theory. The extension of the radiation potential theory for spray combustion and hypersonic flow is also recommended.

  20. Charms of radiation research.

    SciTech Connect

    Inokuti, M.; Physics

    2005-01-01

    Most of my professional efforts over nearly five decades have been devoted to radiation research, that is, studies of the physical, chemical, and biological actions of high-energy radiation on matter. (By the term 'high-energy radiation' I mean here x rays, .GAMMA. rays, neutrons, and charged particles of high enough energies to produce ionization in matter. I exclude visible light, infrared waves, microwaves, and sound waves.) Charms of radiation research lie in its interdisciplinary character; although my training was in basic physics, the scope of my interest has gradually increased to cover many other areas, to my deep satisfaction. High-energy radiation is an important component of the universe, and of our environment. It often provides an effective avenue for characterizing matter and understanding its behavior. Near Earth's surface this radiation is normally present in exceptionally low quantity, and yet it plays a significant role in some atmospheric phenomena such as auroras, and also in the evolution of life. The recent advent of various devices for producing high-energy radiation has opened up the possibility of many applications, including medical and industrial uses. I have worked on some aspects of those uses. At every opportunity to address a broad audience I try to convey a sense of intellectual fun, together with some of the elements of the basic science involved. A goal of radiation education might be to make the word 'radiation' as common and familiar as words such as 'fire' and 'electricity' through increased usage.

  1. Radiation physics, biophysics, and radiation biology

    SciTech Connect

    Hall, E.J.

    1992-05-01

    The following research programs from the Center for Radiological Research of Columbia University are described: Design and development of a new wall-less ultra miniature proportional counter for nanodosimetry; some recent measurements of ionization distributions for heavy ions at nanometer site sizes with a wall-less proportional counter; a calculation of exciton energies in periodic systems with helical symmetry: application to a hydrogen fluoride chain; electron energy-loss function in polynucleotide and the question of plasmon excitation; a non-parametric, microdosimetric-based approach to the evaluation of the biological effects of low doses of ionizing radiation; high-LET radiation risk assessment at medium doses; high-LET radiobiological effects: increased lesion severity or increased lesion proximity; photoneutrons generated by high energy medical linacs; the biological effectiveness of neutrons; implications for radiation protection; molecular characterization of oncogenes induced by neutrons; and the inverse dose-rate effect for oncogenic transformation by charged particles is LET dependent.

  2. Response of LiF:Mg,Ti thermoluminescent dosimeters at photon energies relevant to the dosimetry of brachytherapy (<1 MeV)

    SciTech Connect

    Tedgren, Aasa Carlsson; Hedman, Angelica; Grindborg, Jan-Erik; Carlsson, Gudrun Alm

    2011-10-15

    Purpose: High energy photon beams are used in calibrating dosimeters for use in brachytherapy since absorbed dose to water can be determined accurately and with traceability to primary standards in such beams, using calibrated ion chambers and standard dosimetry protocols. For use in brachytherapy, beam quality correction factors are needed, which include corrections for differences in mass energy absorption properties between water and detector as well as variations in detector response (intrinsic efficiency) with radiation quality, caused by variations in the density of ionization (linear energy transfer (LET) -distributions) along the secondary electron tracks. The aim of this work was to investigate experimentally the detector response of LiF:Mg,Ti thermoluminescent dosimeters (TLD) for photon energies below 1 MeV relative to {sup 60}Co and to address discrepancies between the results found in recent publications of detector response. Methods: LiF:Mg,Ti dosimeters of formulation MTS-N Poland were irradiated to known values of air kerma free-in-air in x-ray beams at tube voltages 25-250 kV, in {sup 137}Cs- and {sup 60}Co-beams at the Swedish Secondary Standards Dosimetry Laboratory. Conversions from air kerma free-in-air into values of mean absorbed dose in the dosimeters in the actual irradiation geometries were made using EGSnrc Monte Carlo simulations. X-ray energy spectra were measured or calculated for the actual beams. Detector response relative to that for {sup 60}Co was determined at each beam quality. Results: An increase in relative response was seen for all beam qualities ranging from 8% at tube voltage 25 kV (effective energy 13 keV) to 3%-4% at 250 kV (122 keV effective energy) and {sup 137}Cs with a minimum at 80 keV effective energy (tube voltage 180 kV). The variation with effective energy was similar to that reported by Davis et al.[Radiat. Prot. Dosim. 106, 33-43 (2003)] with our values being systematically lower by 2%-4%. Compared to the

  3. Radiation Therapy (For Parents)

    MedlinePlus

    ... alike, but remember that many kids treated with radiation therapy go on to live healthy, full lives. Don't hesitate to discuss your questions and concerns with the doctor. The more you know about how radiation therapy will affect and help your child, the ...

  4. Electromagnetic radiation detector

    DOEpatents

    Benson, Jay L.; Hansen, Gordon J.

    1976-01-01

    An electromagnetic radiation detector including a collimating window, a cathode member having a photoelectric emissive material surface angularly disposed to said window whereby radiation is impinged thereon at acute angles, an anode, separated from the cathode member by an evacuated space, for collecting photoelectrons emitted from the emissive cathode surface, and a negatively biased, high transmissive grid disposed between the cathode member and anode.

  5. Radiation in the universe

    NASA Technical Reports Server (NTRS)

    Stuhlinger, Ernst; Truemper, Joachim; Weisskopf, Martin

    1992-01-01

    When Wilhelm Conrad Roentgen discovered radiation one hundred years ago, it seemed that what was discovered was one of the rarest and most volatile members of the family of the basic modules of our natural world. Today cosmologists report that a substantial part of the universe's radiation energy consists of X-rays, which travel through cosmic space with the speed of light.

  6. Radiation effects in space

    SciTech Connect

    Fry, R.J.M.

    1987-07-01

    As more people spend more time in space, and the return to the moon and exploratory missions are considered, the risks require continuing examination. The effects of microgravity and radiation are two potential risks in space. These risks increase with increasing mission duration. This document considers the risk of radiation effects in space workers and explorers. 17 refs., 1 fig., 4 tabs.

  7. Treatment of Radiation Injury

    PubMed Central

    Akita, Sadanori

    2014-01-01

    Significance: Radiation exposure as a result of radiation treatment, accident, or terrorism may cause serious problems such as deficiency due to necrosis or loss of function, fibrosis, or intractable ulcers in the tissues and organs. When the skin, bone, oral mucous membrane, guts, or salivary glands are damaged by ionizing radiation, the management and treatment are very lengthy and difficult. Critical Issues: In severe and irreversible injuries, surgery remains the mainstay of treatment. Several surgical procedures, such as debridement, skin grafting, and local and free-vascularized flaps, are widely used. Recent Advances: In specific cases of major morbidity or in high-risk patients, a newly developed therapy using a patient's own stem cells is safe and effective. Adipose tissue, normally a rich source of mesenchymal stem cells, which are similar to those from the bone marrow, can be harvested, since the procedure is easy, and abundant tissue can be obtained with minimal invasiveness. Future Directions: Based on the molecular basis of radiation injuries, several prospective treatments are under development. Single-nucleotide polymorphisms focus on an individual's sensitivity to radiation in radiogenomics, and the pathology of radiation fibrosis or the effect of radiation on wound healing is being studied and will lead to new insight into the treatment of radiation injuries. Protectors and mitigators are being actively investigated in terms of the timing of administration or dose. PMID:24761339

  8. On Blackbody Radiation.

    ERIC Educational Resources Information Center

    Jain, Pushpendra K.

    1991-01-01

    The interrelationship between the various forms of the Planck radiation equation is discussed. A differential equation that gives intensity or energy density of radiation per unit wavelength or per unit frequency is emphasized. The Stefan-Boltzmann Law and the change in the glow of a hot body with temperature are also discussed. (KR)

  9. Radiation belts of jupiter.

    PubMed

    Stansberry, K G; White, R S

    1973-12-07

    Predictions of Jupiter's electron and proton radiation belts are based mainly on decimeter observations of 1966 and 1968. Extensive calculations modeling radial diffusion of particles inward from the solar wind and electron synchrotron radiation are used to relate the predictions and observations.

  10. Ultraviolet radiation changes

    NASA Technical Reports Server (NTRS)

    Mckenzie, Richard L.; Frederick, John E.; Ilyas, Mohammad; Filyushkin, V.; Wahner, Andreas; Stamnes, K.; Muthusubramanian, P.; Blumthaler, M.; Roy, Colin E.; Madronich, Sasha

    1991-01-01

    A major consequence of ozone depletion is an increase in solar ultraviolet (UV) radiation received at the Earth's surface. This chapter discusses advances that were made since the previous assessment (World Meteorological Organization (WMO)) to our understanding of UV radiation. The impacts of these changes in UV on the biosphere are not included, because they are discussed in the effects assessment.

  11. Radiation treatment of pharmaceuticals

    NASA Astrophysics Data System (ADS)

    Dám, A. M.; Gazsó, L. G.; Kaewpila, S.; Maschek, I.

    1996-03-01

    Product specific doses were calculated for pharmaceuticals to be radiation treated. Radio-pasteurization dose were determined for some heat sensitive pharmaceutical basic materials (pancreaton, neopancreatin, neopancreatin USP, duodenum extract). Using the new recommendation (ISO standards, Method 1) dose calculations were performed and radiation sterilization doses were determined for aprotinine and heparine Na.

  12. Radiation-induced disease.

    PubMed

    Bobrow, M

    1993-01-01

    The term radiation covers a wide spectrum of forms of energy, most of which have at one stage or another been suspected of causing human ill health. In general, study of the effects of radiation on health involves a mix of scientific disciplines, from population epidemiology to physics, which are seldom if ever found in a single scientist. As a result, interdisciplinary communication is of the utmost importance, and is a potent source of misunderstanding and misinformation. The forms of radiation which have been most specifically associated with health effects include ionizing and ultraviolet radiation. Claimed effects of electromagnetic and microwave radiation (excluding thermal effects) are too indefinite for detailed consideration. Ionizing radiation is a well-documented mutagen, which clearly causes cancers in humans, and human exposure has been increased by atomic weapons testing and medical and industrial uses of radioactivity. There is also a growing awareness of the possible role of some types of natural radiation, such as radon, in causing disease. Ultraviolet radiation is also associated with cancers, and is suspected of involvement in the increasing incidence of skin cancers in European populations. Factors thought to underlie recent changes in exposure to these mutagens are discussed.

  13. Instrument for assaying radiation

    DOEpatents

    Coleman, Jody Rustyn; Farfan, Eduardo B.

    2016-03-22

    An instrument for assaying radiation includes a flat panel detector having a first side opposed to a second side. A collimated aperture covers at least a portion of the first side of the flat panel detector. At least one of a display screen or a radiation shield may cover at least a portion of the second side of the flat panel detector.

  14. Transgenerational Radiation Epigenetics

    DTIC Science & Technology

    2011-09-01

    AD_________________ Award Number: W81XWH-10-1-0711 TITLE: Transgenerational Radiation Epigenetics ...5a. CONTRACT NUMBER Transgenerational Radiation Epigenetics 5b. GRANT NUMBER W81XWH-10-1-0711 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S...weeks for preliminary epigenetic screening. Others were used as breeders for transgenerational studies and still others have been left to take when they

  15. Radiation detection system

    DOEpatents

    Franks, Larry A.; Lutz, Stephen S.; Lyons, Peter B.

    1981-01-01

    A radiation detection system including a radiation-to-light converter and fiber optic wave guides to transmit the light to a remote location for processing. The system utilizes fluors particularly developed for use with optical fibers emitting at wavelengths greater than about 500 nm and having decay times less than about 10 ns.

  16. Microcircuit radiation effects databank

    NASA Technical Reports Server (NTRS)

    1983-01-01

    Radiation test data submitted by many testers is collated to serve as a reference for engineers who are concerned with and have some knowledge of the effects of the natural radiation environment on microcircuits. Total dose damage information and single event upset cross sections, i.e., the probability of a soft error (bit flip) or of a hard error (latchup) are presented.

  17. Synchrotron Radiation II.

    ERIC Educational Resources Information Center

    MOSAIC, 1978

    1978-01-01

    Synchrotron radiation is a unique form of radiation that spans the electro-magnetic spectrum from X-rays through the ultraviolet and visible into the infrared. Tunable monochromators enable scientists to select a narrow band of wavelengths at any point in the spectrum. (Author/BB)

  18. Radiation: Doses, Effects, Risks.

    ERIC Educational Resources Information Center

    Lean, Geoffrey, Ed.

    Few scientific issues arouse as much public controversy as the effects of radiation. This booklet is an attempt to summarize what is known about radiation and provide a basis for further discussion and debate. The first four chapters of the booklet are based on the most recent reports to the United Nations' General Assembly by the United Nations…

  19. Radiation-resistant microorganism

    DOEpatents

    Fliermans, Carl B.

    2010-06-15

    An isolated and purified bacterium is provided which was isolated from a high-level radioactive waste site of mixed waste. The isolate has the ability to degrade a wide variety of organic contaminants while demonstrating high tolerance to ionizing radiation. The organism is uniquely suited to bioremediation of a variety or organic contaminants while in the presence of ionizing radiation.

  20. Radiation-resistant microorganism

    DOEpatents

    Fliermans, Carl B.

    2007-01-09

    An isolated and purified bacterium is provided which was isolated from a high-level radioactive waste site of mixed waste. The isolate has the ability to degrade a wide variety of organic contaminants while demonstrating high tolerance to ionizing radiation. The organism is uniquely suited to bioremediation of a variety or organic contaminants while in the presence of ionizing radiation.

  1. Global radiation oncology waybill

    PubMed Central

    Muñoz-Garzón, Victor; Rovirosa, Ángeles; Ramos, Alfredo

    2013-01-01

    Background/aim Radiation oncology covers many different fields of knowledge and skills. Indeed, this medical specialty links physics, biology, research, and formation as well as surgical and clinical procedures and even rehabilitation and aesthetics. The current socio-economic situation and professional competences affect the development and future or this specialty. The aim of this article was to analyze and highlight the underlying pillars and foundations of radiation oncology, indicating the steps implicated in the future developments or competences of each. Methods This study has collected data from the literature and includes highlights from discussions carried out during the XVII Congress of the Spanish Society of Radiation Oncology (SEOR) held in Vigo in June, 2013. Most of the aspects and domains of radiation oncology were analyzed, achieving recommendations for the many skills and knowledge related to physics, biology, research, and formation as well as surgical and clinical procedures and even supportive care and management. Results Considering the data from the literature and the discussions of the XVII SEOR Meeting, the “waybill” for the forthcoming years has been described in this article including all the aspects related to the needs of radiation oncology. Conclusions Professional competences affect the development and future of this specialty. All the types of radio-modulation are competences of radiation oncologists. On the other hand, the pillars of Radiation Oncology are based on experience and research in every area of Radiation Oncology. PMID:24416572

  2. Radiative Flux Analysis

    DOE Data Explorer

    Long, Chuck [NOAA

    2008-05-14

    The Radiative Flux Analysis is a technique for using surface broadband radiation measurements for detecting periods of clear (i.e. cloudless) skies, and using the detected clear-sky data to fit functions which are then used to produce continuous clear-sky estimates. The clear-sky estimates and measurements are then used in various ways to infer cloud macrophysical properties.

  3. RADIATION BIOLOGY: CONCEPTS FOR RADIATION PROTECTION

    EPA Science Inventory

    ABSTRACT

    The opportunity to write a historical review of the field of radiation biology allows for the viewing of the development and maturity of a field of study, thereby being able to provide the appropriate context for the earlier years of research and its findings. The...

  4. Nuclear radiation actuated valve

    DOEpatents

    Christiansen, David W.; Schively, Dixon P.

    1985-01-01

    A nuclear radiation actuated valve for a nuclear reactor. The valve has a valve first part (such as a valve rod with piston) and a valve second part (such as a valve tube surrounding the valve rod, with the valve tube having side slots surrounding the piston). Both valve parts have known nuclear radiation swelling characteristics. The valve's first part is positioned to receive nuclear radiation from the nuclear reactor's fuel region. The valve's second part is positioned so that its nuclear radiation induced swelling is different from that of the valve's first part. The valve's second part also is positioned so that the valve's first and second parts create a valve orifice which changes in size due to the different nuclear radiation caused swelling of the valve's first part compared to the valve's second part. The valve may be used in a nuclear reactor's core coolant system.

  5. Underwater radiation detector

    DOEpatents

    Kruse, Lyle W.; McKnight, Richard P.

    1986-01-01

    A detector apparatus for differentiating between gamma and neutron radiation is provided. The detector includes a pair of differentially shielded Geiger-Mueller tubes. The first tube is wrapped in silver foil and the second tube is wrapped in lead foil. Both the silver and lead foils allow the passage of gamma rays at a constant rate in a gamma ray only field. When neutrons are present, however, the silver activates and emits beta radiation that is also detected by the silver wrapped Geiger-Mueller tube while the radiation detected by the lead wrapped Geiger-Mueller tube remains constant. The amount of radiation impinging on the separate Geiger-Mueller tubes is then correlated in order to distinguish between the neutron and gamma radiations.

  6. Fundamentals of Radiation Dosimetry

    SciTech Connect

    Bos, Adrie J. J.

    2011-05-05

    The basic concepts of radiation dosimetry are reviewed on basis of ICRU reports and text books. The radiation field is described with, among others, the particle fluence. Cross sections for indirectly ionizing radiation are defined and indicated is how they are related to the mass energy transfer and mass energy absorption coefficients. Definitions of total and restricted mass stopping powers of directly ionizing radiation are given. The dosimetric quantities, kerma, absorbed dose and exposure together with the relations between them are discussed in depth. Finally it is indicated how the absorbed dose can be measured with a calorimeter by measuring the temperature increase and with an ionisation chamber measuring the charge produced by the ionizing radiation and making use of the Bragg-Gray relation.

  7. Fundamentals of Radiation Dosimetry

    NASA Astrophysics Data System (ADS)

    Bos, Adrie J. J.

    2011-05-01

    The basic concepts of radiation dosimetry are reviewed on basis of ICRU reports and text books. The radiation field is described with, among others, the particle fluence. Cross sections for indirectly ionizing radiation are defined and indicated is how they are related to the mass energy transfer and mass energy absorption coefficients. Definitions of total and restricted mass stopping powers of directly ionizing radiation are given. The dosimetric quantities, kerma, absorbed dose and exposure together with the relations between them are discussed in depth. Finally it is indicated how the absorbed dose can be measured with a calorimeter by measuring the temperature increase and with an ionisation chamber measuring the charge produced by the ionizing radiation and making use of the Bragg-Gray relation.

  8. Radiation and health*

    PubMed Central

    Lindell, B.

    1987-01-01

    Radiation has been a source of fascination and concern ever since Wilhelm Konrad Röntgen discovered X-rays on 8 November 1895. Over the years, health workers as well as the public have been concerned about medical uses of X-rays, the presence of radon in buildings, radioactive waste from nuclear power stations, fallout from nuclear test explosions, radioactive consumer products, microwave ovens, and many other sources of radiation. Most recently, the tragic accident at the Chernobyl nuclear power station in the USSR, and the subsequent contamination over most of Europe, has again wakened interest and concern and also reminded us about a number of misconceptions about radiation. This article describes the essentials about radiation (especially ionizing radiation) and its health effects. PMID:3496982

  9. Chitosan and radiation chemistry

    NASA Astrophysics Data System (ADS)

    Chmielewski, Andrzej G.

    2010-03-01

    Chitosan as a raw material with special properties has drawn attention of scientists working in the field of radiation processing and natural polymer products development, and also of specialists working in the field of radiation protection and oncologists. Especially the applications concern reduced molecular weight chitosan which still retain its chemical structure; such form of the compound is fostering biological, physical and chemical reactivity of the product. Chitosan degrades into fragments under γ-ray or electron beam irradiation. Antibacterial properties of the product are applied in manufacturing hydrogel for wound dressing and additional healing properties can be achieved by incorporating in the hydrogel matrix chitosan bonded silver clusters. Another possible application of chitosan is in reducing radiation damage to the radiation workers or radiation cured patients. In the case of radioisotopes oral or respiratory chitosan-based materials can be applied as chelators. Applications of chitosan in oncology are also reported.

  10. [Remote radiation planning support system].

    PubMed

    Atsumi, Kazushige; Nakamura, Katsumasa; Yoshidome, Satoshi; Shioyama, Yoshiyuki; Sasaki, Tomonari; Ohga, Saiji; Yoshitake, Tadamasa; Shinoto, Makoto; Asai, Kaori; Sakamoto, Katsumi; Hirakawa, Masakazu; Honda, Hiroshi

    2012-08-01

    We constructed a remote radiation planning support system between Kyushu University Hospital (KUH) in Fukuoka and Kyushu University Beppu Hospital (KBH) in Oita. Between two institutions, radiology information system for radiotherapy division (RT-RIS) and radiation planning system (RTPS) were connected by virtual private network (VPN). This system enables the radiation oncologists at KUH to perform radiotherapy planning for the patients at KBH. The detail of the remote radiation planning support system in our institutions is as follows: The radiation oncologist at KBH performs radiotherapy planning and the data of the patients are sent anonymously to the radiation oncologists at KUH. The radiation oncologists at KUH receive the patient's data, access to RTPS at KBH, verify or change the radiation planning at KBH: Radiation therapy is performed at KBH according to the confirmed plan by the radiation oncologists at KUH. Our remote radiation planning system is useful for providing radiation therapy with safety and accuracy.

  11. Using ProtMAX to create high-mass-accuracy precursor alignments from label-free quantitative mass spectrometry data generated in shotgun proteomics experiments.

    PubMed

    Egelhofer, Volker; Hoehenwarter, Wolfgang; Lyon, David; Weckwerth, Wolfram; Wienkoop, Stefanie

    2013-03-01

    Recently, new software tools have been developed for improved protein quantification using mass spectrometry (MS) data. However, there are still limitations especially in high-sample-throughput quantification methods, and most of these relate to extensive computational calculations. The mass accuracy precursor alignment (MAPA) strategy has been shown to be a robust method for relative protein quantification. Its major advantages are high resolution, sensitivity and sample throughput. Its accuracy is data dependent and thus best suited for precursor mass-to-charge precision of ∼1 p.p.m. This protocol describes how to use a software tool (ProtMAX) that allows for the automated alignment of precursors from up to several hundred MS runs within minutes without computational restrictions. It comprises features for 'ion intensity count' and 'target search' of a distinct set of peptides. This procedure also includes the recommended MS settings for complex quantitative MAPA analysis using ProtMAX (http://www.univie.ac.at/mosys/software.html).

  12. Modifying Radiation Damage

    PubMed Central

    Kim, Kwanghee; McBride, William H.

    2011-01-01

    Radiation leaves a fairly characteristic footprint in biological materials, but this is rapidly all but obliterated by the canonical biological responses to the radiation damage. The innate immune recognition systems that sense “danger” through direct radiation damage and through associated collateral damage set in motion a chain of events that, in a tissue compromised by radiation, often unwittingly result in oscillating waves of molecular and cellular responses as tissues attempt to heal. Understanding “nature’s whispers” that inform on these processes will lead to novel forms of intervention targeted more precisely towards modifying them in an appropriate and timely fashion so as to improve the healing process and prevent or mitigate the development of acute and late effects of normal tissue radiation damage, whether it be accidental, as a result of a terrorist incident, or of therapeutic treatment of cancer. Here we attempt to discuss some of the non-free radical scavenging mechanisms that modify radiation responses and comment on where we see them within a conceptual framework of an evolving radiation-induced lesion. PMID:20583981

  13. Microenvironment and Radiation Therapy

    PubMed Central

    Yoshimura, Michio; Itasaka, Satoshi; Harada, Hiroshi; Hiraoka, Masahiro

    2013-01-01

    Dependency on tumor oxygenation is one of the major features of radiation therapy and this has led many radiation biologists and oncologists to focus on tumor hypoxia. The first approach to overcome tumor hypoxia was to improve tumor oxygenation by increasing oxygen delivery and a subsequent approach was the use of radiosensitizers in combination with radiation therapy. Clinical use of some of these approaches was promising, but they are not widely used due to several limitations. Hypoxia-inducible factor 1 (HIF-1) is a transcription factor that is activated by hypoxia and induces the expression of various genes related to the adaptation of cellular metabolism to hypoxia, invasion and metastasis of cancer cells and angiogenesis, and so forth. HIF-1 is a potent target to enhance the therapeutic effects of radiation therapy. Another approach is antiangiogenic therapy. The combination with radiation therapy is promising, but several factors including surrogate markers, timing and duration, and so forth have to be optimized before introducing it into clinics. In this review, we examined how the tumor microenvironment influences the effects of radiation and how we can enhance the antitumor effects of radiation therapy by modifying the tumor microenvironment. PMID:23509762

  14. Beneficial uses of radiation

    SciTech Connect

    Fox, M.R.

    1991-10-01

    An overall decline in technical literacy within the American public has come at a time when technological advances are accelerating in the United States and around the world. This had led to a large communication gulf between the general public and the technologists. Nowhere is this more evident then with the topic of radiation. Regrettably, too few people know about sources of radiation, the pervasiveness, amounts, and variabilities, and do not have a true understanding of the environment in which we live. Nor do many people know that radiation has been used in beneficial ways for decades around the world. While the general public does not know of the scientific applications to which radiation has been deployed, it nevertheless had benefited tremendously from these efforts. Thanks to the well know properties of radiation, scientific ingenuity has found many uses of radiation in chemical and agricultural research, biomedical research, in the diagnoses and treatment of hundreds of types of diseases, in industrial applications, food irradiation, and many others. This paper provides a sample of the types of uses to which radiation has been used to help advance the betterment of humankind.

  15. Biological Effects of Ionizing Radiation

    DOE R&D Accomplishments Database

    Ingram, M.; Mason, W. B.; Whipple, G. H.; Howland, J. W.

    1952-04-07

    This report presents a review of present knowledge and concepts of the biological effects of ionizing radiations. Among the topics discussed are the physical and chemical effects of ionizing radiation on biological systems, morphological and physiological changes observed in biological systems subjected to ionizing radiations, physiological changes in the intact animal, latent changes following exposure of biological systems to ionizing radiations, factors influencing the biological response to ionizing radiation, relative effects of various ionizing radiations, and biological dosimetry.

  16. Stimulated coherent transition radiation

    SciTech Connect

    Hung-chi Lihn

    1996-03-01

    Coherent radiation emitted from a relativistic electron bunch consists of wavelengths longer than or comparable to the bunch length. The intensity of this radiation out-numbers that of its incoherent counterpart, which extends to wavelengths shorter than the bunch length, by a factor equal to the number of electrons in the bunch. In typical accelerators, this factor is about 8 to 11 orders of magnitude. The spectrum of the coherent radiation is determined by the Fourier transform of the electron bunch distribution and, therefore, contains information of the bunch distribution. Coherent transition radiation emitted from subpicosecond electron bunches at the Stanford SUNSHINE facility is observed in the far-infrared regime through a room-temperature pyroelectric bolometer and characterized through the electron bunch-length study. To measure the bunch length, a new frequency-resolved subpicosecond bunch-length measuring system is developed. This system uses a far-infrared Michelson interferometer to measure the spectrum of coherent transition radiation through optical autocorrelation with resolution far better than existing time-resolved methods. Hence, the radiation spectrum and the bunch length are deduced from the autocorrelation measurement. To study the stimulation of coherent transition radiation, a special cavity named BRAICER is invented. Far-infrared light pulses of coherent transition radiation emitted from electron bunches are delayed and circulated in the cavity to coincide with subsequent incoming electron bunches. This coincidence of light pulses with electron bunches enables the light to do work on electrons, and thus stimulates more radiated energy. The possibilities of extending the bunch-length measuring system to measure the three-dimensional bunch distribution and making the BRAICER cavity a broadband, high-intensity, coherent, far-infrared light source are also discussed.

  17. Liquid sheet radiator

    NASA Technical Reports Server (NTRS)

    Chubb, Donald L.; White, K. Alan, III

    1987-01-01

    A new external flow radiator concept, the liquid sheet radiator (LSR), is introduced. The LSR sheet flow is described and an expression for the length/width (l/w), ratio is presented. A linear dependence of l/w on velocity is predicted that agrees with experimental results. Specific power for the LSR is calculated and is found to be nearly the same as the specific power of a liquid droplet radiator, (LDR). Several sheet thicknesses and widths were experimentally investigated. In no case was the flow found to be unstable.

  18. Ethics and radiation protection.

    PubMed

    Hansson, Sven Ove

    2007-06-01

    Some of the major problems in radiation protection are closely connected to issues that have a long, independent tradition in moral philosophy. This contribution focuses on two of these issues. One is the relationship between the protection of individuals and optimisation on the collective level, and the other is the relative valuation of future versus immediate damage. Some of the intellectual tools that have been developed by philosophers can be useful in radiation protection. On the other hand, philosophers have much to learn from radiation protectors, not least when it comes to finding pragmatic solutions to problems that may be intractable in principle.

  19. Human radiation tolerance

    NASA Technical Reports Server (NTRS)

    Lushbaugh, C. C.

    1974-01-01

    The acute radiation syndrome in man is clinically bounded by death at high dose levels and by the prodromal syndrome of untoward physiological effects at minimal levels of clinically effective exposure. As in lower animals, man experiences principally three acute modes of death from radiation exposure (Bond et al., 1965). These are known collectively as the lethal radiation syndromes: central nervous system death, gastrointestinal death, and hematopoietic death. The effect of multiple exposure on lethality, the effect of multiple exposure on hematopoietic recovery, and quantitative aspects of cell and tissue repair are discussed.

  20. Radiation Safety System

    SciTech Connect

    Vylet, Vaclav; Liu, James C.; Walker, Lawrence S.; /Los Alamos

    2012-04-04

    The goal of this work is to provide an overview of a Radiation safety system (RSS) designed for protection from prompt radiation hazard at accelerator facilities. RSS design parameters, functional requirements and constraints are derived from hazard analysis and risk assessment undertaken in the design phase of the facility. The two main subsystems of a RSS are access control system (ACS) and radiation control system (RCS). In this text, a common approach to risk assessment, typical components of ACS and RCS, desirable features and general design principles applied to RSS are described.

  1. Radiative forcing of climate

    NASA Technical Reports Server (NTRS)

    Ramanswamy, V.; Shine, Keith; Leovy, Conway; Wang, Wei-Chyung; Rodhe, Henning; Wuebbles, Donald J.; Ding, M.; Lelieveld, Joseph; Edmonds, Jae A.; Mccormick, M. Patrick

    1991-01-01

    An update of the scientific discussions presented in Chapter 2 of the Intergovernmental Panel on Climate Change (IPCC) report is presented. The update discusses the atmospheric radiative and chemical species of significance for climate change. There are two major objectives of the present update. The first is an extension of the discussion on the Global Warming Potentials (GWP's), including a reevaluation in view of the updates in the lifetimes of the radiatively active species. The second important objective is to underscore major developments in the radiative forcing of climate due to the observed stratospheric ozone losses occurring between 1979 and 1990.

  2. Microcircuit radiation effects databank

    NASA Technical Reports Server (NTRS)

    1983-01-01

    This databank is the collation of radiation test data submitted by many testers and serves as a reference for engineers who are concerned with and have some knowledge of the effects of the natural radiation environment on microcircuits. It contains radiation sensitivity results from ground tests and is divided into two sections. Section A lists total dose damage information, and section B lists single event upset cross sections, I.E., the probability of a soft error (bit flip) or of a hard error (latchup).

  3. Radiation therapy in horses.

    PubMed

    Fidel, Janean L

    2010-04-01

    Although the diagnosis of cancer is relatively uncommon in horses, tumors do occur in this species. Surgery, radiation, and chemotherapy are traditional cancer treatments in all species. In equine patients, surgery has often been the only treatment offered; however, not all tumors can be controlled with surgery alone. In small animal oncology, newer and better therapies are in demand and available. Radiation therapy is often used to control or palliate tumors locally, especially to satisfy clients who demand sophisticated treatments. The large size of equine patients can make radiation therapy difficult, but it is a valuable tool for treating cancer and should not be overlooked when treating horses.

  4. Fast multilevel radiative transfer

    NASA Astrophysics Data System (ADS)

    Paletou, Frédéric; Léger, Ludovick

    2007-01-01

    The vast majority of recent advances in the field of numerical radiative transfer relies on approximate operator methods better known in astrophysics as Accelerated Lambda-Iteration (ALI). A superior class of iterative schemes, in term of rates of convergence, such as Gauss-Seidel and Successive Overrelaxation methods were therefore quite naturally introduced in the field of radiative transfer by Trujillo Bueno & Fabiani Bendicho (1995); it was thoroughly described for the non-LTE two-level atom case. We describe hereafter in details how such methods can be generalized when dealing with non-LTE unpolarised radiation transfer with multilevel atomic models, in monodimensional geometry.

  5. Composition for radiation shielding

    DOEpatents

    Kronberg, James W.

    1994-01-01

    A composition for use as a radiation shield. The shield has a depleted urum core for absorbing gamma rays and a bismuth coating for preventing chemical corrosion and absorbing gamma rays. Alternatively, a sheet of gadolinium may be positioned between the uranium core and the bismuth coating for absorbing neutrons. The composition is preferably in the form of a container for storing materials that emit radiation such as gamma rays and neutrons. The container is preferably formed by casting bismuth around a pre-formed uranium container having a gadolinium sheeting, and allowing the bismuth to cool. The resulting container is a structurally sound, corrosion-resistant, radiation-absorbing container.

  6. Miniaturized radiation chirper

    DOEpatents

    Umbarger, C. John; Wolf, Michael A.

    1980-01-01

    The disclosure relates to a miniaturized radiation chirper for use with a small battery supplying on the order of 5 volts. A poor quality CdTe crystal which is not necessarily suitable for high resolution gamma ray spectroscopy is incorporated with appropriate electronics so that the chirper emits an audible noise at a rate that is proportional to radiation exposure level. The chirper is intended to serve as a personnel radiation warning device that utilizes new and novel electronics with a novel detector, a CdTe crystal. The resultant device is much smaller and has much longer battery life than existing chirpers.

  7. Radiation physics, biophysics, and radiation biology

    NASA Astrophysics Data System (ADS)

    Hall, E. J.; Zaider, M.

    1990-05-01

    This annual report contains a summary of our current research. Some highlights include: experimental microdosimetry, track structure, extension of the Dual Radiation Action model to be time dependent, experiments showing that the reverse dose-rate effect for onogenic transformation, first rated for neutrons, has also been observed for charged particles of intermediate LET, an analysis of low dose-rate, research in hyperthermia, studies in molecular cloning, low dose rate studies, experimental studies on high LET, and molecular studies on DNA.

  8. Recent Developments of the Local Effect Model (LEM) - Implications of clustered damage on cell transformation

    NASA Astrophysics Data System (ADS)

    Elsässer, Thilo

    predict the risk of the complex mixed radiation field occurring in deep space. 1. F. A. Cucinotta and M. Durante, Lancet Oncol. 7, 431-435 (2006). 2. M. Scholz and G. Kraft, Radiat. Prot. Dosim. 52, 29-33 (1994). 3. Th. Els¨sser and M. Scholz, Radiat. Res. 167, 319-329 (2007). a 4. R. C. Miller, S. A. Marino, D. J. Brenner, S. G. Martin, M. Richards, G. Randers-Pehrson, and E. J. Hall, Radiat. Res. 142, 54-60 (1995).

  9. Lecture on Thermal Radiation

    NASA Technical Reports Server (NTRS)

    Dennis, Brian R.

    2006-01-01

    This lecture will cover solar thermal radiation, particularly as it relates to the high energy solar processes that are the subject of this summer school. After a general review of thermal radiation from the Sun and a discussion of basic definitions, the various emission and absorption mechanisms will be described including black-body emission, bremsstrahlung, free-bound, and atomic line emissions of all kinds. The bulk of the time will be spent discussing the observational characteristics of thermal flare plasma and what can be learned about the flare energy release process from observations of the thermal radiation at all wavelengths. Information that has been learned about the morphology, temperature distribution, and composition of the flare plasma will be presented. The energetics of the thermal flare plasma will be discussed in relation to the nonthermal energy of the particles accelerated during the flare. This includes the total energy, the radiated and conductive cooling processes, and the total irradiated energy.

  10. Ionizing radiation detector

    DOEpatents

    Thacker, Louis H.

    1990-01-01

    An ionizing radiation detector is provided which is based on the principle of analog electronic integration of radiation sensor currents in the sub-pico to nano ampere range between fixed voltage switching thresholds with automatic voltage reversal each time the appropriate threshold is reached. The thresholds are provided by a first NAND gate Schmitt trigger which is coupled with a second NAND gate Schmitt trigger operating in an alternate switching state from the first gate to turn either a visible or audible indicating device on and off in response to the gate switching rate which is indicative of the level of radiation being sensed. The detector can be configured as a small, personal radiation dosimeter which is simple to operate and responsive over a dynamic range of at least 0.01 to 1000 R/hr.

  11. Radiation Therapy for Cancer

    MedlinePlus

    ... being studied as potential radioprotectors. The use of carbon ion beams in radiation therapy is being investigated ... time, the use of these beams remains experimental. Carbon ion beams are available at only a few ...

  12. Amorphous silicon radiation detectors

    DOEpatents

    Street, Robert A.; Perez-Mendez, Victor; Kaplan, Selig N.

    1992-01-01

    Hydrogenated amorphous silicon radiation detector devices having enhanced signal are disclosed. Specifically provided are transversely oriented electrode layers and layered detector configurations of amorphous silicon, the structure of which allow high electric fields upon application of a bias thereby beneficially resulting in a reduction in noise from contact injection and an increase in signal including avalanche multiplication and gain of the signal produced by incoming high energy radiation. These enhanced radiation sensitive devices can be used as measuring and detection means for visible light, low energy photons and high energy ionizing particles such as electrons, x-rays, alpha particles, beta particles and gamma radiation. Particular utility of the device is disclosed for precision powder crystallography and biological identification.

  13. Blackbody Radiation Tables

    DTIC Science & Technology

    at the indicated wavelength and temperature, Planck’s equation . This equation represents the monochromatic radiant intensity at a particular wavelength from a perfect radiator maintained at the indicated temperature.

  14. Radiation Exposure and Pregnancy

    MedlinePlus

    ... Gynecol 200(1):4-24; 2009. International Atomic Energy Agency. Pregnancy and radiation protection in diagnostic radiology, radiotherapy and nuclear medicine. 2010. Available at: http: / / rpop. iaea. org/ ...

  15. The Space Radiation Environment

    NASA Technical Reports Server (NTRS)

    Bourdarie, Sebastien; Xapsos, Michael A.

    2008-01-01

    The effects of the space radiation environment on spacecraft systems and instruments are significant design considerations for space missions. Astronaut exposure is a serious concern for manned missions. In order to meet these challenges and have reliable, cost-effective designs, the radiation environment must be understood and accurately modeled. The nature of the environment varies greatly between low earth orbits, higher earth orbits and interplanetary space. There are both short-term and long-term variations with the phase of the solar cycle. In this paper we concentrate mainly on charged particle radiations. Descriptions of the radiation belts and particles of solar and cosmic origin are reviewed. An overview of the traditional models is presented accompanied by their application areas and limitations. This is followed by discussion of some recent model developments.

  16. Radiation-Induced Bioradicals

    NASA Astrophysics Data System (ADS)

    Lahorte, Philippe; Mondelaers, Wim

    This chapter represents the second part of a review in which the production and application of radiation-induced radicals in biological matter are discussed. In part one the general aspects of the four stages (physical, physicochemical, chemical and biological) of interaction of radiation with matter in general and biological matter in particular, were discussed. Here an overview is presented of modem technologies and theoretical methods available for studying these radiation effects. The relevance is highlighted of electron paramagnetic resonance spectroscopy and quantum chemical calculations with respect to obtaining structural information on bioradicals, and a survey is given of the research studies in this field. We also discuss some basic aspects of modem accelerator technologies which can be used for creating radicals and we conclude with an overview of applications of radiation processing in biology and related fields such as biomedical and environmental engineering, food technology, medicine and pharmacy.

  17. Amorphous silicon radiation detectors

    DOEpatents

    Street, R.A.; Perez-Mendez, V.; Kaplan, S.N.

    1992-11-17

    Hydrogenated amorphous silicon radiation detector devices having enhanced signal are disclosed. Specifically provided are transversely oriented electrode layers and layered detector configurations of amorphous silicon, the structure of which allow high electric fields upon application of a bias thereby beneficially resulting in a reduction in noise from contact injection and an increase in signal including avalanche multiplication and gain of the signal produced by incoming high energy radiation. These enhanced radiation sensitive devices can be used as measuring and detection means for visible light, low energy photons and high energy ionizing particles such as electrons, x-rays, alpha particles, beta particles and gamma radiation. Particular utility of the device is disclosed for precision powder crystallography and biological identification. 13 figs.

  18. Volcanic Aerosol Radiative Properties

    NASA Technical Reports Server (NTRS)

    Lacis, Andrew

    2015-01-01

    Large sporadic volcanic eruptions inject large amounts of sulfur bearing gases into the stratosphere which then get photochemically converted to sulfuric acid aerosol droplets that exert a radiative cooling effect on the global climate system lasting for several years.

  19. Space radiation studies

    NASA Technical Reports Server (NTRS)

    Gregory, J. C.

    1986-01-01

    Instrument design and data analysis expertise was provided in support of several space radiation monitoring programs. The Verification of Flight Instrumentation (VFI) program at NASA included both the Active Radiation Detector (ARD) and the Nuclear Radiation Monitor (NRM). Design, partial fabrication, calibration and partial data analysis capability to the ARD program was provided, as well as detector head design and fabrication, software development and partial data analysis capability to the NRM program. The ARD flew on Spacelab-1 in 1983, performed flawlessly and was returned to MSFC after flight with unchanged calibration factors. The NRM, flown on Spacelab-2 in 1985, also performed without fault, not only recording the ambient gamma ray background on the Spacelab, but also recording radiation events of astrophysical significance.

  20. Nanotechnology in radiation oncology.

    PubMed

    Wang, Andrew Z; Tepper, Joel E

    2014-09-10

    Nanotechnology, the manipulation of matter on atomic and molecular scales, is a relatively new branch of science. It has already made a significant impact on clinical medicine, especially in oncology. Nanomaterial has several characteristics that are ideal for oncology applications, including preferential accumulation in tumors, low distribution in normal tissues, biodistribution, pharmacokinetics, and clearance, that differ from those of small molecules. Because these properties are also well suited for applications in radiation oncology, nanomaterials have been used in many different areas of radiation oncology for imaging and treatment planning, as well as for radiosensitization to improve the therapeutic ratio. In this article, we review the unique properties of nanomaterials that are favorable for oncology applications and examine the various applications of nanotechnology in radiation oncology. We also discuss the future directions of nanotechnology within the context of radiation oncology.

  1. Radiation Therapy (For Parents)

    MedlinePlus

    ... temporary, it can be permanent. Sore Mouth and Tooth Decay The tissues of the mouth may be sore ... and there may be an increased risk of tooth decay if a child received radiation therapy to the ...

  2. Portal radiation monitor

    DOEpatents

    Kruse, L.W.

    1982-03-23

    A portal radiation monitor combines .1% FAR with high sensitivity to special nuclear material. The monitor utilizes pulse shape discrimination, dynamic compression of the photomultiplier output and scintillators sized to maintain efficiency over the entire portal area.

  3. Portal radiation monitor

    DOEpatents

    Kruse, Lyle W.

    1985-01-01

    A portal radiation monitor combines 0.1% FAR with high sensitivity to special nuclear material. The monitor utilizes pulse shape discrimination, dynamic compression of the photomultiplier output and scintillators sized to maintain efficiency over the entire portal area.

  4. Observations on radiation myelopathy.

    PubMed

    Godwin-Austen, R B; Howell, D A; Worthington, B

    1975-12-01

    Three cases of radiation myelopathy are reported. Corticosteroid therapy was associated with worth-while remissions in 2 patients. Two patients showed swelling of the spinal cord in myelograms and in one it extended below the irradiated part of the spinal cord. Demyelination of the dorsal white columns of the spinal cord unaccompanied by vascular abnormality was seen below the irradiated part of the cord. It is suggested that radiation damages the endothelial cell barrier of capillaries and arterioles after a latent interval. Proteinous oedema fluid spreads through the white matter from the capillaries and also into the arteriolar walls narrowing these vessels enough to cause local ischaemia and infarction. It is further suggested that apart from ischaemia and infarction myelin is also damaged by poor nutrition associated with oedema fluid, and that radiation damage to oligodendroglial cells is not the cause of this additional demyelination in patients with radiation myelopathy.

  5. Tin Can Radiation Detector.

    ERIC Educational Resources Information Center

    Crull, John L.

    1986-01-01

    Provides instructions for making tin can radiation detectors from empty aluminum cans, aluminum foil, clear plastic, copper wire, silica gel, and fine, unwaxed dental floss put together with tape or glue. Also provides suggestions for activities using the detectors. (JN)

  6. GEWEX Radiative Flux Assessment

    Atmospheric Science Data Center

    2016-05-20

    ... climate components (atmosphere, ocean, land, cryosphere, biosphere). The GEWEX Radiative Flux Assessment (RFA) project will provide a ... Spatial Coverage: (-20.45, -2.43)(-62.87, -47.90) Full Product Page ...

  7. Nanotechnology in Radiation Oncology

    PubMed Central

    Wang, Andrew Z.; Tepper, Joel E.

    2014-01-01

    Nanotechnology, the manipulation of matter on atomic and molecular scales, is a relatively new branch of science. It has already made a significant impact on clinical medicine, especially in oncology. Nanomaterial has several characteristics that are ideal for oncology applications, including preferential accumulation in tumors, low distribution in normal tissues, biodistribution, pharmacokinetics, and clearance, that differ from those of small molecules. Because these properties are also well suited for applications in radiation oncology, nanomaterials have been used in many different areas of radiation oncology for imaging and treatment planning, as well as for radiosensitization to improve the therapeutic ratio. In this article, we review the unique properties of nanomaterials that are favorable for oncology applications and examine the various applications of nanotechnology in radiation oncology. We also discuss the future directions of nanotechnology within the context of radiation oncology. PMID:25113769

  8. Radiation and Society

    ERIC Educational Resources Information Center

    Shaw, Edward I.

    1974-01-01

    Presents a discussion of the risks, to society, from radiation-associated technologies and urges that science teachers help the public understand the decision-making process relative to nuclear power as well as the problems and alternatives. (PEB)

  9. SU-E-T-249: Neutron Model Upgrade for Radiotherapy Patients Monitoring Using a New Online Detector

    SciTech Connect

    Irazola, L; Sanchez Doblado, F.; Lorenzoli, M; Pola, A.; Terron, J.A.; Bedogni, R.; Sanchez Nieto, B.; Romero-Exposito, M.

    2014-06-01

    Purpose: The purpose of this work is to improve the existing methodology to estimate neutron equivalent dose in organs during radiotherapy treatments, based on a Static Random Access Memory neutron detector (SRAMnd) [1]. This is possible thanks to the introduction of a new digital detector with improved characteristics, which is able to measure online the neutron fluence rate in the presence of an intense photon background [2]. Its reduced size, allows the direct estimation of doses in specific points inside an anthropomorphic phantom (NORMA) without using passive detectors as TLD or CR-39. This versatility will allow not only to improve the existing models (generic abdomen and H and N [1]) but to generate more specific ones for any technique. Methods: The new Thermal Neutron Rate Detector (TNRD), based on a diode device sensitized to thermal neutrons, have been inserted in 16 points of the phantom. These points are distributed to infer doses to specific organs. Simultaneous measurements of these devices and a reference one, located in front of the gantry, have been performed for the mentioned generic treatments, in order to improve the existing model. Results: These new devices have shown more precise since they agree better with Monte Carlo simulations. The comparison of the thermal neutron fluence, measured with TNRD, and the existing models, converted from events to fluence, shows an average improvement of (3.90±3.37) % for H and N and (12.61±9.43) % for abdomen, normalized to the maximum value. Conclusion: This work indicates the potential of these new devices for more precise neutron equivalent dose estimation in organs, as a consequence of radiotherapy treatments. The simplicity of the process makes possible to establish more specific models that will provide a better dose estimation. References[1] Phys Med Biol 2012; 57:6167–6191.[2] A new active thermal neutron detector. Radiat. Prot. Dosim. (in press)

  10. Indoor inhalation dose estimates due to radon and thoron in some areas of South-Western Punjab, India.

    PubMed

    Kumar, Sanjeev; Singh, Surinder; Bajwa, Bikramjit Singh; Singh, Bhupinder; Sabharwal, Arvind D; Eappen, K P

    2012-08-01

    LR-115 (type II)-based radon-thoron discriminating twin-chamber dosemeters have been used for estimating radon ((222)Rn) and thoron ((220)Rn) concentrations in dwellings of south-western Punjab, India. The present study region has shown pronounced cases of cancer incidents in the public [Thakur, Rao, Rajwanshi, Parwana and Kumar (Epidemiological study of high cancer among rural agricultural community of Punjab in Northern India. Int J Environ Res Public Health 2008; 5(5):399-407) and Kumar et al. (Risk assessment for natural uranium in subsurface water of Punjab state, India. Hum Ecol Risk Assess 2011;17:381-93)]. Radon being a carcinogen has been monitored in some dwellings selected randomly in the study area. Results show that the values of radon ((222)Rn)  varied from 21 to 79 Bq m(-3), with a geometric mean of 45 Bq m(-3) [geometric standard deviation (GSD 1.39)], and those of thoron ((220)Rn)  from minimum detection level to 58 Bq m(-3) with a geometric mean of 19 Bq m(-3) (GSD 1.88). Bare card data are used for computing the progeny concentration by deriving the equilibrium factor (F) using a root finding method [Mayya, Eappen and Nambi (Methodology for mixed field inhalation dosimetry in monazite areas using a twin-cup dosemeter with three track detectors. Radiat Prot Dosim 1998;77(3):177-84)]. Inhalation doses have been calculated and compared using UNSCEAR equilibrium factors and by using the calculated F-values. The results show satisfactory comparison between the values.

  11. Radiation detection system

    DOEpatents

    Whited, R.C.

    A system for obtaining improved resolution in relatively thick semiconductor radiation detectors, such as HgI/sub 2/, which exhibit significant hole trapping. Two amplifiers are used: the first measures the charge collected and the second the contribution of the electrons to the charge collected. The outputs of the two amplifiers are utilized to unfold the total charge generated within the detector in response to a radiation event.

  12. Radiative transfer dynamo effect

    NASA Astrophysics Data System (ADS)

    Munirov, Vadim R.; Fisch, Nathaniel J.

    2017-01-01

    Magnetic fields in rotating and radiating astrophysical plasma can be produced due to a radiative interaction between plasma layers moving relative to each other. The efficiency of current drive, and with it the associated dynamo effect, is considered in a number of limits. It is shown here, however, that predictions for these generated magnetic fields can be significantly higher when kinetic effects, previously neglected, are taken into account.

  13. Auditing radiation sterilization facilities

    NASA Astrophysics Data System (ADS)

    Beck, Jeffrey A.

    The diversity of radiation sterilization systems available today places renewed emphasis on the need for thorough Quality Assurance audits of these facilities. Evaluating compliance with Good Manufacturing Practices is an obvious requirement, but an effective audit must also evaluate installation and performance qualification programs (validation_, and process control and monitoring procedures in detail. The present paper describes general standards that radiation sterilization operations should meet in each of these key areas, and provides basic guidance for conducting QA audits of these facilities.

  14. Radiative transfer dynamo effect

    DOE PAGES

    Munirov, Vadim R.; Fisch, Nathaniel J.

    2017-01-17

    Here, magnetic fields in rotating and radiating astrophysical plasma can be produced due to a radiative interaction between plasma layers moving relative to each other. The efficiency of current drive, and with it the associated dynamo effect, is considered in a number of limits. It is shown here, however, that predictions for these generated magnetic fields can be significantly higher when kinetic effects, previously neglected, are taken into account.

  15. Method of enhancing radiation response of radiation detection materials

    DOEpatents

    Miller, Steven D.

    1997-01-01

    The present invention is a method of increasing radiation response of a radiation detection material for a given radiation signal by first pressurizing the radiation detection material. Pressurization may be accomplished by any means including mechanical and/or hydraulic. In this application, the term "pressure" includes fluid pressure and/or mechanical stress.

  16. Packet personal radiation monitor

    DOEpatents

    Phelps, James E.

    1989-01-01

    A personal radiation monitor of the chirper type is provided for detecting ionizing radiation. A battery powered high voltage power supply is used to generate and apply a high voltage bias to a G-M tube radiation sensor. The high voltage is monitored by a low-loss sensing network which generates a feedback signal to control the high voltage power supply such that the high voltage bias is recharged to +500 VDC when the current pulses of the sensor, generated by the detection of ionizing radiation events, discharges the high voltage bias to +450 VDC. During the high voltage recharge period an audio transducer is activated to produce an audible "chirp". The rate of the "chirps" is controlled by the rate at which the high voltage bias is recharged, which is proportional to the radiation field intensity to which the sensor is exposed. The chirp rate sensitivity is set to be approximately 1.5 (chirps/min/MR/hr.). The G-M tube sensor is used in a current sensing mode so that the device does not paralyze in a high radiation field.

  17. Radiator Design and Installation

    NASA Technical Reports Server (NTRS)

    Brevoort, M.J.; Leifer, M.

    1939-01-01

    The fundamental principles of fluid flow, pressure losses, and heat transfer have been presented and analyzed for the case of a smooth tube with fully developed turbulent flow. These equations apply to tubes with large length-diameter ratios where the f1ow is at a high Reynolds Number. The error introduced by using these equations increases as the magnitude of the tube length and the air-flow Reynolds Number approaches the values encountered in modern radiator designs. Accordingly, heat-transfer tests on radiator sections were made and the results are presented in nondimensional form to facilitate their use and for comparison with other heat-transfer data. In addition, pressure losses were measured along smooth tubes of circular, square, and rectangular cross section and the results were also correlated and are presented in nondimensional form. The problem of a radiator design for a particular installation is solved, the experimental heat-transfer and pressure-loss data being used, on a basis of power chargeable to the radiator for form drag, for propelling the weight, and for forcing the air through the radiator. The case of an installation within a wing or an engine nacelle is considered. An illustration of radiator design is carried through for an arbitrary set of conditions. Sufficient detail is given to enable the reader to reproduce the analysis for any given case.

  18. Antarctic radiation exposure doubles

    NASA Astrophysics Data System (ADS)

    Blue, Charles

    New data reveal that the Antarctic Peninsula received twice its normal maximum dose of hazardous solar ultraviolet radiation in December 1990. The prolonged persistence of the ozone hole over Antarctica caused an increased exposure of radiation, according to a paper published in the October issue of Geophysical Research Letters.John Frederick and Amy D. Alberts of the University of Chicago calculated the amount of ultraviolet solar spectral radiation from data collected at Palmer Station, Antarctica. During the spring of 1990 the largest observed values for ultraviolet radiation were approximately double the values expected, based on previous years. “The measurements from Palmer Station are consistent with similar data from McMurdo Sound, where a factor of three [ultraviolet radiation] enhancement was recorded, according to work by Knut Stamnes and colleagues at the University of Alaska,” Frederick said. “The radiation levels observed over Palmer Station in December 1990 may be the largest experienced in this region of the world since the development of the Earth's ozone layer,” he added.

  19. Fabric space radiators

    SciTech Connect

    Antoniak, Z.I.; Krotiuk, W.J.; Webb, B.J.; Prater, J.T.; Bates, J.M.

    1988-01-01

    Future Air Force space missions will require thermal radiators that both survive in the hostile space environment and stow away for minimal bulk during launch. Advances in all aspects of radiator design, construction, and analysis will be necessary to enable such future missions. Currently, the best means for obtaining high strength along with flexibility is through structures known as fabrics. The development of new materials and bonding techniques has extended the application range of fabrics into areas traditionally dominated by monolithic and/or metallic structures. Given that even current spacecraft heat rejection considerations tend to dominate spacecraft design and mass, the larger and more complex designs of the future face daunting challenges in thermal control. Ceramic fabrics bonded to ultra-thin metal liners (foils) have the potential of achieving radiator performance levels heretofore unattainable, and of readily matching the advances made in other branches of spacecraft design. The research effort documented here indicates that both pumped loops and heat pipes constructed in ceramic fabrics stand to benefit in multiple ways. Flexibility and low mass are the main advantages exhibited by fabric radiators over conventional metal ones. We feel that fabric radiators have intrinsic merits not possessed by any other radiator design and need to be researched further. 26 refs., 16 figs., 17 tabs.

  20. Electrostatic space radiation shielding

    NASA Astrophysics Data System (ADS)

    Tripathi, Ram K.; Wilson, John W.; Youngquist, Robert C.

    2008-09-01

    For the success of NASA’s new vision for space exploration to Moon, Mars and beyond, exposures from the hazards of severe space radiation in deep space long duration missions is ‘a must solve’ problem. The payload penalty demands a very stringent requirement on the design of the spacecrafts for human deep space missions. The exploration beyond low Earth orbit (LEO) to enable routine access of space will require protection from the hazards of the accumulated exposures of space radiation, Galactic Cosmic Rays (GCR) and Solar Particle Events (SPE), and minimizing the production of secondary radiation is a great advantage. There is a need to look to new horizons for newer technologies. The present investigation revisits electrostatic active radiation shielding and explores the feasibility of using the electrostatic shielding in concert with the state-of-the-art materials shielding and protection technologies. The full space radiation environment has been used, for the first time, to explore the feasibility of electrostatic shielding. The goal is to repel enough positive charge ions so that they miss the spacecraft without attracting thermal electrons. Conclusions are drawn for the future directions of space radiation protection.

  1. Acute radiation syndrome caused by accidental radiation exposure - therapeutic principles.

    PubMed

    Dörr, Harald; Meineke, Viktor

    2011-11-25

    Fortunately radiation accidents are infrequent occurrences, but since they have the potential of large scale events like the nuclear accidents of Chernobyl and Fukushima, preparatory planning of the medical management of radiation accident victims is very important. Radiation accidents can result in different types of radiation exposure for which the diagnostic and therapeutic measures, as well as the outcomes, differ. The clinical course of acute radiation syndrome depends on the absorbed radiation dose and its distribution. Multi-organ-involvement and multi-organ-failure need be taken into account. The most vulnerable organ system to radiation exposure is the hematopoietic system. In addition to hematopoietic syndrome, radiation induced damage to the skin plays an important role in diagnostics and the treatment of radiation accident victims. The most important therapeutic principles with special reference to hematopoietic syndrome and cutaneous radiation syndrome are reviewed.

  2. Radiation analysis devices, radiation analysis methods, and articles of manufacture

    DOEpatents

    Roybal, Lyle Gene

    2010-06-08

    Radiation analysis devices include circuitry configured to determine respective radiation count data for a plurality of sections of an area of interest and combine the radiation count data of individual of sections to determine whether a selected radioactive material is present in the area of interest. An amount of the radiation count data for an individual section is insufficient to determine whether the selected radioactive material is present in the individual section. An article of manufacture includes media comprising programming configured to cause processing circuitry to perform processing comprising determining one or more correction factors based on a calibration of a radiation analysis device, measuring radiation received by the radiation analysis device using the one or more correction factors, and presenting information relating to an amount of radiation measured by the radiation analysis device having one of a plurality of specified radiation energy levels of a range of interest.

  3. Gravitational radiation resistance, radiation damping and field fluctuations

    NASA Astrophysics Data System (ADS)

    Schaefer, G.

    1981-03-01

    Application is made of two different generalized fluctuation-dissipation theorems and their derivations to the calculation of the gravitational quadrupole radiation resistance using the radiation-reaction force given by Misner, Thorne and Wheeler and the usual tidal force on one hand and the tidal force and the free gravitational radiation field on the other hand. The quantum-mechanical version (including thermal generalizations) of the well known classical quadrupole radiation damping formula is obtained as a function of the radiation resistance.

  4. Radiation nephritis causing nephrotic syndrome

    SciTech Connect

    Jennette, J.C.; Ordonez, N.G.

    1983-12-01

    Clinical symptoms of acute radiation nephritis with nephrotic syndrome developed in a fifty-six-year-old woman after abdominal radiation therapy for an astrocytoma of the spinal cord. The diagnosis of radiation nephritis was confirmed by renal biopsy. To our knowledge, this is the first documented case of radiation nephritis associated with nephrotic syndrome.

  5. Interaction of Radiation with Matter

    SciTech Connect

    Rickards, J.

    2010-09-10

    A flash introductory course in the interaction of ionizing radiation with matter is presented for students starting out in nuclear physics, medical applications of radiation, materials modification, radiation damage, detectors, materials analysis, radiation protection, and other applications. Emphasis is on defining basic concepts and on a simple visualization of ideas for practical applications, rather than on completeness or rigor.

  6. Radiation Sensitization in Cancer Therapy.

    ERIC Educational Resources Information Center

    Greenstock, Clive L.

    1981-01-01

    Discusses various aspects of radiation damage to biological material, including free radical mechanisms, radiation sensitization and protection, tumor hypoxia, mechanism of hypoxic cell radiosensitization, redox model for radiation modification, sensitizer probes of cellular radiation targets, pulse radiolysis studies of free radical kinetics,…

  7. Ionizing radiation bioeffects and risks

    SciTech Connect

    1992-12-31

    Radiation protection requires an understanding of the prompt and long-term biological effects of radiation and numerical estimates of radiation risks. This chapter presents the characteristics of the ``acute radiation syndrome`` which can occur if an individual is exposed to high doses of radiation, and the effects of high levels of radiation on the skin. It also describes the long term bioeffects of low levels of low LET radiation on individuals and the whole population. These risks are quantified and are put in perspective by comparison to other societal hazards.

  8. Radiation health research, 1986 - 1990

    NASA Technical Reports Server (NTRS)

    1991-01-01

    A collection of 225 abstracts of radiation research sponsored by NASA during the period 1986 through 1990 is reported. Each abstract was categorized within one of four discipline areas: physics, biology, risk assessment, and microgravity. Topic areas within each discipline were assigned as follows: Physics - atomic physics, nuclear science, space radiation, radiation transport and shielding, and instrumentation; Biology - molecular biology, cellular radiation biology, tissue, organs and organisms, radioprotectants, and plants; Risk assessment - radiation health and epidemiology, space flight radiation health physics, inter- and intraspecies extrapolation, and radiation limits and standards; and Microgravity. When applicable subareas were assigned for selected topic areas. Keywords and author indices are provided.

  9. Radiation in Particle Simulations

    SciTech Connect

    More, R; Graziani, F; Glosli, J; Surh, M

    2010-11-19

    Hot dense radiative (HDR) plasmas common to Inertial Confinement Fusion (ICF) and stellar interiors have high temperature (a few hundred eV to tens of keV), high density (tens to hundreds of g/cc) and high pressure (hundreds of megabars to thousands of gigabars). Typically, such plasmas undergo collisional, radiative, atomic and possibly thermonuclear processes. In order to describe HDR plasmas, computational physicists in ICF and astrophysics use atomic-scale microphysical models implemented in various simulation codes. Experimental validation of the models used to describe HDR plasmas are difficult to perform. Direct Numerical Simulation (DNS) of the many-body interactions of plasmas is a promising approach to model validation but, previous work either relies on the collisionless approximation or ignores radiation. We present four methods that attempt a new numerical simulation technique to address a currently unsolved problem: the extension of molecular dynamics to collisional plasmas including emission and absorption of radiation. The first method applies the Lienard-Weichert solution of Maxwell's equations for a classical particle whose motion is assumed to be known. The second method expands the electromagnetic field in normal modes (planewaves in a box with periodic boundary-conditions) and solves the equation for wave amplitudes coupled to the particle motion. The third method is a hybrid molecular dynamics/Monte Carlo (MD/MC) method which calculates radiation emitted or absorbed by electron-ion pairs during close collisions. The fourth method is a generalization of the third method to include small clusters of particles emitting radiation during close encounters: one electron simultaneously hitting two ions, two electrons simultaneously hitting one ion, etc. This approach is inspired by the virial expansion method of equilibrium statistical mechanics. Using a combination of these methods we believe it is possible to do atomic-scale particle simulations of

  10. Bile Duct (Cholangiocarcinoma) Cancer: Radiation Therapy

    MedlinePlus

    ... Situation Bile Duct Cancer Treating Bile Duct Cancer Radiation Therapy for Bile Duct Cancer Radiation therapy uses ... of radiation for bile duct cancer. External beam radiation therapy (EBRT) This type of radiation therapy uses ...

  11. Radiation delivery system and method

    DOEpatents

    Sorensen, Scott A.; Robison, Thomas W.; Taylor, Craig M. V.

    2002-01-01

    A radiation delivery system and method are described. The system includes a treatment configuration such as a stent, balloon catheter, wire, ribbon, or the like, a portion of which is covered with a gold layer. Chemisorbed to the gold layer is a radiation-emitting self-assembled monolayer or a radiation-emitting polymer. The radiation delivery system is compatible with medical catheter-based technologies to provide a therapeutic dose of radiation to a lesion following an angioplasty procedure.

  12. Status of LDEF radiation modeling

    NASA Technical Reports Server (NTRS)

    Watts, John W.; Armstrong, T. W.; Colborn, B. L.

    1995-01-01

    The current status of model prediction and comparison with LDEF radiation dosimetry measurements is summarized with emphasis on major results obtained in evaluating the uncertainties of present radiation environment model. The consistency of results and conclusions obtained from model comparison with different sets of LDEF radiation data (dose, activation, fluence, LET spectra) is discussed. Examples where LDEF radiation data and modeling results can be utilized to provide improved radiation assessments for planned LEO missions (e.g., Space Station) are given.

  13. User Perceptions of ¡Protéjase!: An Intervention Designed to Increase Protective Equipment Use Among Mexican Immigrant and Mexican American Farmworkers

    PubMed Central

    Montiel-Ishino, Francisco A; Smyth, Joshua M; Murphy, Dennis J; Miranda, Patricia Y; Davis, Lisa A

    2016-01-01

    Background Farmworkers’ exposures to pesticides are reduced when they wear personal protective equipment (PPE), and mobile health (mHealth) platforms can potentially deliver information to farmworkers to help promote PPE use. However, little is known about the feasibility of using mHealth platforms to promote farmworkers’ use of PPE. Objective The objective of the study was to describe the development and feasibility-testing of Protect Yourself! (¡Protéjase!), an intervention designed to increase PPE use. As the vast majority of farmworkers in the United States are from Mexico, we examined the intervention in a primarily Mexican-origin farmworker population. Methods ¡Protéjase was developed in several steps. First, we performed ethnographic observations to understand what prevents PPE use. Next, we developed program components that met the challenges uncovered in the ethnographic observations, seeking direct feedback from farmworkers on each component. Feasibility was assessed using surveys and focus groups. Material was provided in Spanish or English at the preference of the participant. Finally, we pilot tested each component of the intervention, including: (1) PPE that was provided to each worker for their personal use during the intervention trial, and (2) delivery of an application-based tool that promoted the use of PPE through daily individualized messaging. Results 55 farmworkers enrolled in the study, but only 41 of 55 (75%) completed the entire pilot intervention trial. Results focus on the evaluation of the intervention, and include only those who completed the entire trial. Among farmworkers who completed the entire intervention trial, all but two farmworkers were born in Mexico and were Spanish speaking. Still, all study participants self-identified as Mexican or Mexican-American. When asked what changes were needed in the intervention’s messaging or delivery to increase user satisfaction, 22 out of 41 participants (54%) felt that no changes

  14. AREA RADIATION MONITOR

    DOEpatents

    Manning, F.W.; Groothuis, S.E.; Lykins, J.H.; Papke, D.M.

    1962-06-12

    S>An improved area radiation dose monitor is designed which is adapted to compensate continuously for background radiation below a threshold dose rate and to give warning when the dose integral of the dose rate of an above-threshold radiation excursion exceeds a selected value. This is accomplished by providing means for continuously charging an ionization chamber. The chamber provides a first current proportional to the incident radiation dose rate. Means are provided for generating a second current including means for nulling out the first current with the second current at all values of the first current corresponding to dose rates below a selected threshold dose rate value. The second current has a maximum value corresponding to that of the first current at the threshold dose rate. The excess of the first current over the second current, which occurs above the threshold, is integrated and an alarm is given at a selected integrated value of the excess corresponding to a selected radiation dose. (AEC)

  15. Packet personal radiation monitor

    DOEpatents

    Phelps, J.E.

    1988-03-31

    A personal radiation monitor of the chirper type is provided for detecting ionizing radiation. A battery powered high voltage power supply is used to generate and apply a high voltage bias to a G-M tube radiation sensor. The high voltage is monitored by a low-loss sensing network which generates a feedback signal to control the high voltage power supply such that the high voltage bias is recharged to +500 VDC when the current pulses of the sensor, generated by the detection of ionizing radiatonevents, discharges the high voltage bias to +450 VDC. During the high voltage recharge period an audio transducer is activated to produce an audible ''chirp''. The rate of the ''chirps'' is controlled by the rate at which the high voltage bias is recharged, which is proportional to the radiation field intensity to which the sensor is exposed. The chirp rate sensitivity is set to be approximately 1.5 (chirps/min/MR/hr.). The G-M tube sensor is used in a current sensing mode so that the device does not paralyze in a high radiation field. 2 figs.

  16. Remote radiation dosimetry

    DOEpatents

    Braunlich, Peter F.; Tetzlaff, Wolfgang; Hegland, Joel E.; Jones, Scott C.

    1991-01-01

    Disclosed are methods and apparatus for remotely measuring radiation levels. Such are particularly useful for measuring relatively high levels or dosages of radiation being administered in radiation therapy. They are also useful for more general radiation level measurements where remote sensing from the remaining portions of the apparatus is desirable. The apparatus uses a beam generator, such as a laser beam, to provide a stimulating beam. The stimulating beam is preferably of wavelengths shorter than 6 microns, or more advantageously less than 2 microns. The stimulating beam is used to stimulate a remote luminescent sensor mounted in a probe which emits stored luminescent energy resulting from exposure of the sensor to ionizing radiation. The stimulating beam is communicated to the remote luminescent sensor via transmissive fiber which also preferably serves to return the emission from the luminescent sensor. The stimulating beam is advantageously split by a beam splitter to create a detector beam which is measured for power during a reading period during which the luminescent phosphor is read. The detected power is preferably used to control the beam generator to thus produce desired beam power during the reading period. The luminescent emission from the remote sensor is communicated to a suitable emission detector, preferably after filtering or other selective treatment to better isolate the luminescent emission.

  17. Remote radiation dosimetry

    DOEpatents

    Braunlich, P.F.; Tetzlaff, W.; Hegland, J.E.; Jones, S.C.

    1991-03-12

    Disclosed are methods and apparatus for remotely measuring radiation levels. Such are particularly useful for measuring relatively high levels or dosages of radiation being administered in radiation therapy. They are also useful for more general radiation level measurements where remote sensing from the remaining portions of the apparatus is desirable. The apparatus uses a beam generator, such as a laser beam, to provide a stimulating beam. The stimulating beam is preferably of wavelengths shorter than 6 microns, or more advantageously less than 2 microns. The stimulating beam is used to stimulate a remote luminescent sensor mounted in a probe which emits stored luminescent energy resulting from exposure of the sensor to ionizing radiation. The stimulating beam is communicated to the remote luminescent sensor via a transmissive fiber which also preferably serves to return the emission from the luminescent sensor. The stimulating beam is advantageously split by a beam splitter to create a detector beam which is measured for power during a reading period during which the luminescent phosphor is read. The detected power is preferably used to control the beam generator to thus produce desired beam power during the reading period. The luminescent emission from the remote sensor is communicated to a suitable emission detector, preferably after filtering or other selective treatment to better isolate the luminescent emission. 8 figures.

  18. Lunar radiator shade

    NASA Technical Reports Server (NTRS)

    Ewert, Michael K. (Inventor)

    1992-01-01

    An apparatus for rejecting waste heat from a system located on or near the lunar equator is presented. The system utilizes a reflective catenary shaped trough deployed about a vertical radiator to shade the radiator from heat emitted by the hot lunar surface. The catenary shaped trough is constructed from a film material and is aligned relative to the sun so that incoming solar energy is focused to a line just above the vertical radiator and can thereby isolate the radiator from the effects of direct sunlight. The film is in a collapsed position between side by side support rods, all of which are in a transport case. To deploy the film and support rods, a set of parallel tracks running perpendicular to length of the support rods are extended out from the transport case. After the support tracks are deployed, the support rods are positioned equidistant from each other along the length of the support tracks so that the flexible film shade between adjacent support rods is unfolded and hangs in a catenary shaped trough. A heat radiator is supported between each pair of support rods above each hanging reflective trough.

  19. Ionizing radiation and life.

    PubMed

    Dartnell, Lewis R

    2011-01-01

    Ionizing radiation is a ubiquitous feature of the Cosmos, from exogenous cosmic rays (CR) to the intrinsic mineral radioactivity of a habitable world, and its influences on the emergence and persistence of life are wide-ranging and profound. Much attention has already been focused on the deleterious effects of ionizing radiation on organisms and the complex molecules of life, but ionizing radiation also performs many crucial functions in the generation of habitable planetary environments and the origins of life. This review surveys the role of CR and mineral radioactivity in star formation, generation of biogenic elements, and the synthesis of organic molecules and driving of prebiotic chemistry. Another major theme is the multiple layers of shielding of planetary surfaces from the flux of cosmic radiation and the various effects on a biosphere of violent but rare astrophysical events such as supernovae and gamma-ray bursts. The influences of CR can also be duplicitous, such as limiting the survival of surface life on Mars while potentially supporting a subsurface biosphere in the ocean of Europa. This review highlights the common thread that ionizing radiation forms between the disparate component disciplines of astrobiology.

  20. Radiative Forcing by Contrails

    NASA Technical Reports Server (NTRS)

    Meerkoetter, R.; Schumann, U.; Doelling, D. R.; Nakajima, T.; Tsushima, Y.

    1999-01-01

    A parametric study of the instantaneous radiative impact of contrails is presented using three different radiative transfer models for a series of model atmospheres and cloud parameters. Contrails are treated as geometrically and optically thin plane parallel homogeneous cirrus layers in a static atmospheres The ice water content is varied as a function of ambient temperature. The model atmospheres include tropical, mid-latitude, and subarctic summer and winter atmospheres Optically thin contrails cause a positive net forcing at top of the atmosphere. At the surface the radiative forcing is negative during daytime. The forcing increases with the optical depth and the amount of contrail cover. At the top of the atmosphere a mean contrail cover of 0.1% with average optical depth of 0.2 to 0.5 causes about 0.01 to 0.03 W/m(exp 2)a daily mean instantaneous radiative forcing. Contrails cool the surface during the day and heat the surface during the night, and hence reduce the daily temperature amplitude The net effect depends strongly on the daily variation of contrail cloud cover. The indirect radiative forcing due to particle changes in natural cirrus clouds may be of the same magnitude as the direct one due to additional cover.

  1. Reducing Radiation Damage

    SciTech Connect

    Blankenbecler, Richard

    2006-06-05

    This talk describes the use of a modified treatment sequence, i.e., radiation dose, geometry, dwell time, etc., to mitigate some of the deleterious effects of cancer radiotherapy by utilizing natural cell repair processes. If bad side effects can be reduced, a more aggressive therapy can be put into place. Cells contain many mechanisms that repair damage of various types. If the damage can not be repaired, cells will undergo apoptosis (cell death). Data will be reviewed that support the fact that a small dose of radiation will activate damage repair genes within a cell. Once the mechanisms are fully active, they will efficiently repair the severe damage from a much larger radiation dose. The data ranges from experiments on specific cell cultures using microarray (gene chip) techniques to experiments on complete organisms. The suggested effect and treatment is consistent with the assumption that all radiation is harmful, no matter how small the dose. Nevertheless, the harm can be reduced. These mechanisms need to be further studied and characterized. In particular, their time dependence needs to be understood before the proposed treatment can be optimized. Under certain situations it is also possible that the deleterious effects of chemotherapy can be mitigated and the damage to radiation workers can be reduced.

  2. Radiation from Relativistic Jets

    NASA Technical Reports Server (NTRS)

    Nishikawa, K.-I.; Mizuno, Y.; Hardee, P.; Sol, H.; Medvedev, M.; Zhang, B.; Nordlund, A.; Frederiksen, J. T.; Fishman, G. J.; Preece, R.

    2008-01-01

    Nonthermal radiation observed from astrophysical systems containing relativistic jets and shocks, e.g., gamma-ray bursts (GRBs), active galactic nuclei (AGNs), and Galactic microquasar systems usually have power-law emission spectra. Recent PIC simulations of relativistic electron-ion (electron-positron) jets injected into a stationary medium show that particle acceleration occurs within the downstream jet. In the presence of relativistic jets, instabilities such as the Buneman instability, other two-streaming instability, and the Weibel (filamentation) instability create collisionless shocks, which are responsible for particle (electron, positron, and ion) acceleration. The simulation results show that the Weibel instability is responsible for generating and amplifying highly nonuniform, small-scale magnetic fields. These magnetic fields contribute to the electron's transverse deflection behind the jet head. The 'jitter' radiation from deflected electrons in small-scale magnetic fields has different properties than synchrotron radiation which is calculated in a uniform magnetic field. This jitter radiation, a case of diffusive synchrotron radiation, may be important to understand the complex time evolution and/or spectral structure in gamma-ray bursts, relativistic jets, and supernova remnants.

  3. neXtA5: accelerating annotation of articles via automated approaches in neXtProt

    PubMed Central

    Mottin, Luc; Gobeill, Julien; Pasche, Emilie; Michel, Pierre-André; Cusin, Isabelle; Gaudet, Pascale; Ruch, Patrick

    2016-01-01

    implemented into the neXtProt annotation pipeline. Available on: http://babar.unige.ch:8082/neXtA5 Database URL: http://babar.unige.ch:8082/neXtA5/fetcher.jsp PMID:27374119

  4. Radiation techniques for acromegaly

    PubMed Central

    2011-01-01

    Radiotherapy (RT) remains an effective treatment in patients with acromegaly refractory to medical and/or surgical interventions, with durable tumor control and biochemical remission; however, there are still concerns about delayed biochemical effect and potential late toxicity of radiation treatment, especially high rates of hypopituitarism. Stereotactic radiotherapy has been developed as a more accurate technique of irradiation with more precise tumour localization and consequently a reduction in the volume of normal tissue, particularly the brain, irradiated to high radiation doses. Radiation can be delivered in a single fraction by stereotactic radiosurgery (SRS) or as fractionated stereotactic radiotherapy (FSRT) in which smaller doses are delivered over 5-6 weeks in 25-30 treatments. A review of the recent literature suggests that pituitary irradiation is an effective treatment for acromegaly. Stereotactic techniques for GH-secreting pituitary tumors are discussed with the aim to define the efficacy and potential adverse effects of each of these techniques. PMID:22136376

  5. Solar cell radiation handbook

    NASA Technical Reports Server (NTRS)

    Tada, H. Y.; Carter, J. R., Jr.; Anspaugh, B. E.; Downing, R. G.

    1982-01-01

    The handbook to predict the degradation of solar cell electrical performance in any given space radiation environment is presented. Solar cell theory, cell manufacturing and how they are modeled mathematically are described. The interaction of energetic charged particles radiation with solar cells is discussed and the concept of 1 MeV equivalent electron fluence is introduced. The space radiation environment is described and methods of calculating equivalent fluences for the space environment are developed. A computer program was written to perform the equivalent fluence calculations and a FORTRAN listing of the program is included. Data detailing the degradation of solar cell electrical parameters as a function of 1 MeV electron fluence are presented.

  6. [Acute radiation injury].

    PubMed

    Saito, Tsutomu

    2012-03-01

    Cell death due to DNA damage by ionizing radiation causes acute radiation injury of tissues and organs. Frequency and severity of the injuries increase according to dose increase, when the dose becomes more than threshold dose. The threshold dose of acute human radiation death is 1 Gy and LD50 of human is 4 Gy. Human dies due to the cerebrovascular syndrome, the gastrointestinal syndrome or the hematopoetic syndrome, when he received more than 20 Gy, 10-20 Gy or 3-8 Gy to his total body, respectively. Any tissue or organ, including embryo and fetus, does not show the acute injury, when it received less than 100 mSv. Acute injuries are usually reversible, and late injuries are sometimes irreversible.

  7. Jupiter's radiation belts.

    NASA Technical Reports Server (NTRS)

    Brice, N.; Mcdonough, T. R.

    1973-01-01

    A model for the production and loss of energetic electrons in Jupiter's radiation belt is presented. It is postulated that the electrons originate in the solar wind and are diffused in toward the planet by perturbations which violate the particles' third adiabatic invariant. At large distances, magnetic perturbations, electric fields associated with magnetospheric convection, or interchange instabilities driven by thermal plasma gradients may drive the diffusion. Inside about 10 Jupiter radii, the diffusion is probably driven by electric fields associated with the upper atmosphere dynamo which is driven by neutral winds in the ionosphere. The diurnal component of the dynamo wind fields produces a dawn-dusk asymmetry in the decimetric radiation from the electrons in the belts, and the lack of obvious measured asymmetries in the decimetric radiation measurements provides estimates of upper limits for these Jovian ionospheric neutral winds.

  8. Radiation exposure during ureteroscopy

    SciTech Connect

    Bagley, D.H.; Cubler-Goodman, A. )

    1990-12-01

    Use of fluoroscopy during ureteroscopy increases the risk of radiation exposure to the urologist and patient. Radiation entrance dosages were measured at skin level in 37 patients, and at the neck, trunk and finger of the urologist, and neck and trunk of the circulating nurse. Radiation exposure time was measured in 79 patients, and was related to the purpose of the procedure and the type of ureteroscope used, whether rigid or flexible. Exposure could be minimized by decreasing the fluoroscopy time. A portable C-arm fluoroscopy unit with electronic imaging and last image hold mode should be used to minimize exposure time. Lead aprons and thyroid shields should be used by the urologist and other personnel in the endoscopy room.

  9. Composition for radiation shielding

    DOEpatents

    Kronberg, J.W.

    1994-08-02

    A composition for use as a radiation shield is disclosed. The shield has a depleted uranium core for absorbing gamma rays and a bismuth coating for preventing chemical corrosion and absorbing gamma rays. Alternatively, a sheet of gadolinium may be positioned between the uranium core and the bismuth coating for absorbing neutrons. The composition is preferably in the form of a container for storing materials that emit radiation such as gamma rays and neutrons. The container is preferably formed by casting bismuth around a pre-formed uranium container having a gadolinium sheeting, and allowing the bismuth to cool. The resulting container is a structurally sound, corrosion-resistant, radiation-absorbing container. 2 figs.

  10. Audible radiation monitor

    DOEpatents

    Odell, Daniel M. C.

    1993-01-01

    A method and apparatus for monitoring ionizing radiation comprising radiation detectors in electrical connection with an isotopic analyzer and a device for producing chords to which each isotope is mapped so that the device produces a unique chord for each isotope. Preferably the chords are pleasing to the ear, except for chords representing unexpected isotopes, and are louder or softer depending on the level of radioactivity produced by each isotope, and musical instrument voices may be simulated in producing the chords as an aid to distinguishing similar-sounding chords. Because of the representation by chords, information regarding the level and composition of the radiation in an area can be conveyed to workers in that area more effectively and yet without distracting them.

  11. Radiation Protection in Canada

    PubMed Central

    Duggan, H. E.

    1964-01-01

    Factors that may reduce the dose of radiation, from diagnostic and therapeutic x-ray procedures, to the patient and to the occupational and non-occupational worker are outlined. Suitable basic radiation measuring apparatus is described. It is recommended that, in diagnostic radiography, relatively high kilovoltage, proper cones, collimation and adequate filtration be used. Some specific recommendations are made concerning fluoroscopic, photoroentgen and portable x-ray examinations. Film monitoring of personnel is advisable. Examples are given of protective devices to lessen the dosage to the occupational worker. It is the responsibility of the radiologist or physician in charge to ensure that the x-ray equipment is safe to operate and the radiation dose to the patient is kept to a minimum. The roentgen output for all radiographic examinations should be known by the responsible user. ImagesFig. 2Fig. 3Fig. 4Fig. 5 PMID:14199820

  12. String radiative backreaction

    SciTech Connect

    Battye, R.A.; Shellard, E.P. |

    1995-12-01

    We discuss radiative backreaction for global strings described by the Kalb-Ramond action with an analogous derivation to that for the point electron in classical electrodynamics. We show how local corrections to the equations of motion allow one to separate the self-field of the string from that of the radiation field. Modifications to this {open_quote}{open_quote}local backreaction approximation{close_quote}{close_quote} circumvent the runaway solutions, allowing these corrections to be used to evolve string trajectories numerically. Comparisons are made with analytic and numerical radiation calculations from previous work and the merits and limitations of this approach are discussed. {copyright} {ital 1995 The American Physical Society.}

  13. Radiation Protection in Canada

    PubMed Central

    Brown, John R.; Jarvis, Anita A.

    1964-01-01

    A recent survey was carried out with respect to radiobiological and radiological health projects in Canada. Letters of inquiry, followed by two questionnaires, were sent out to every institution where radiation research was likely to have been undertaken. Approximately 75% of those contacted replied. Of the total of 200 studies, 84% were classified as biological and medical studies, the remaining 16% as environmental radiation studies. Responses to the inquiry stressed the inadequacy of the present governmental budget for radiation research, the need for higher salaries for research workers, and the necessity of a more intensive teaching program for technicians and professional personnel. The granting of longer-term grants, rather than annually renewable grants, is urged. PMID:14226104

  14. Radiation Induced Oral Mucositis

    PubMed Central

    PS, Satheesh Kumar; Balan, Anita; Sankar, Arun; Bose, Tinky

    2009-01-01

    Patients receiving radiotherapy or chemotherapy will receive some degree of oral mucositis The incidence of oral mucositis was especially high in patients: (i) With primary tumors in the oral cavity, oropharynx, or nasopharynx; (ii) who also received concomitant chemotherapy; (iii) who received a total dose over 5,000 cGy; and (iv) who were treated with altered fractionation radiation schedules. Radiation-induced oral mucositis affects the quality of life of the patients and the family concerned. The present day management of oral mucositis is mostly palliative and or supportive care. The newer guidelines are suggesting Palifermin, which is the first active mucositis drug as well as Amifostine, for radiation protection and cryotherapy. The current management should focus more on palliative measures, such as pain management, nutritional support, and maintenance, of good oral hygiene PMID:20668585

  15. Aerothermodynamic radiation studies

    NASA Technical Reports Server (NTRS)

    Donohue, K.; Reinecke, W. G.; Rossi, D.; Marinelli, W. J.; Krech, R. H.; Caledonia, G. E.

    1991-01-01

    We have built and made operational a 6 in. electric arc driven shock tube which alloys us to study the non-equilibrium radiation and kinetics of low pressure (0.1 to 1 torr) gases processed by 6 to 12 km/s shock waves. The diagnostic system allows simultaneous monitoring of shock radiation temporal histories by a bank of up to six radiometers, and spectral histories with two optical multi-channel analyzers. A data set of eight shots was assembled, comprising shocks in N2 and air at pressures between 0.1 and 1 torr and velocities of 6 to 12 km/s. Spectrally resolved data was taken in both the non-equilibrium and equilibrium shock regions on all shots. The present data appear to be the first spectrally resolved shock radiation measurements in N2 performed at 12 km/s. The data base was partially analyzed with salient features identified.

  16. Audible radiation monitor

    SciTech Connect

    Odell, D.M.C.

    1992-12-31

    This invention consists of a method and apparatus for monitoring ionizing radiation comprising radiation detectors in electrical connection with an isotopic analyzer and a device for producing chords to which each isotope is mapped so that the device produces a unique chord for each isotope. Preferably the chords are pleasing to the ear, except for chords representing unexpected isotopes, and are louder or softer depending on the level of radioactivity produced by each isotope, and musical instrument voices may be simulated in producing the chords as an aid to distinguishing similar-sounding chords. Because of the representation by chords, information regarding the level and composition of the radiation in an area can be conveyed to workers in that area more effectively and yet without distracting them.

  17. Pediatric radiation oncology

    SciTech Connect

    Halperin, E.C.; Kun, L.E.; Constine, L.S.; Tarbell, N.J.

    1989-01-01

    This text covers all aspects of radiation therapy for treatment of pediatric cancer. The book describes the proper use of irradiation in each of the malignancies of childhood, including tumors that are rarely encountered in adult practice. These include acute leukemia; supratentorial brain tumors; tumors of the posterior fossa of the brain and spinal canal; retinoblastoma and optic nerve glioma; neuroblastoma; Hodgkin's disease; malignant lymphoma; Ewing's sarcoma; osteosarcoma; rhabdomyosarcoma; Desmoid tumor; Wilms' tumor; liver and biliary tumors; germ cell and stromal cell tumors of the gonads; endocrine, aerodigestive tract, and breast tumors; Langerhans' cell histiocytosis; and skin cancer and hemangiomas. For each type of malignancy, the authors describe the epidemiology, common presenting signs and symptoms, staging, and proper diagnostic workup. Particular attention is given to the indications for radiation therapy and the planning of a course of radiotherapy, including the optimal radiation dose, field size, and technique.

  18. Semiconductor radiation detector

    DOEpatents

    Bell, Zane W.; Burger, Arnold

    2010-03-30

    A semiconductor detector for ionizing electromagnetic radiation, neutrons, and energetic charged particles. The detecting element is comprised of a compound having the composition I-III-VI.sub.2 or II-IV-V.sub.2 where the "I" component is from column 1A or 1B of the periodic table, the "II" component is from column 2B, the "III" component is from column 3A, the "IV" component is from column 4A, the "V" component is from column 5A, and the "VI" component is from column 6A. The detecting element detects ionizing radiation by generating a signal proportional to the energy deposited in the element, and detects neutrons by virtue of the ionizing radiation emitted by one or more of the constituent materials subsequent to capture. The detector may contain more than one neutron-sensitive component.

  19. Radiation rate meter development

    SciTech Connect

    Thacker, L.H.

    1989-01-01

    We are still in a very preliminary stage of examining the potentials of a new series of instruments which may be inexpensive and versatile enough to complement, or conceivably even replace, electroscope dosimeters in Civil Defense and other situations requiring radiation monitoring by the general public. These instruments were developed to provide a qualitative signal so simple to interpret that anyone can tell immediately whether they are in a dangerous radiation field, and whether they are moving into a hotter area or a cooler area. A second goal in the development has been to produce the simplest possible device at minimum cost, without compromise in effectiveness. In the simplest implementation the device is essentially a very inexpensive version of the much older Personal Radiation Monitor (PRM).

  20. Small Active Radiation Monitor

    NASA Technical Reports Server (NTRS)

    Badhwar, Gautam D.

    2004-01-01

    A device, named small active radiation monitor, allows on-orbit evaluations during periods of increased radiation, after extravehicular activities, or at predesignated times for crews on such long-duration space missions as on the International Space Station. It also permits direct evaluation of biological doses, a task now performed using a combination of measurements and potentially inaccurate simulations. Indeed the new monitor can measure a full array of radiation levels, from soft x-rays to hard galactic cosmic-ray particles. With refinement, it will benefit commercial (nuclear power-plant workers, airline pilots, medical technicians, physicians/dentists, and others) and military personnel as well as the astronauts for whom thermoluminescent dosimeters are inadequate. Civilian and military personnel have long since graduated from film badges to thermoluminescent dosimeters. Once used, most dosimeters must be returned to a central facility for processing, a step that can take days or even weeks. While this suffices for radiation workers for whom exposure levels are typically very low and of brief duration, it does not work for astronauts. Even in emergencies and using express mail, the results can often be delayed by as much as 24 hours. Electronic dosimeters, which are the size of electronic oral thermometers, and tattlers, small electronic dosimeters that sound an alarm when the dose/dose rate exceeds preset values, are also used but suffer disadvantages similar to those of thermoluminescent dosimeters. None of these devices fully answers the need of rapid monitoring during the space missions. Instead, radiation is monitored by passive detectors, which are read out after the missions. Unfortunately, these detectors measure only the absorbed dose and not the biologically relevant dose equivalent. The new monitor provides a real-time readout, a time history of radiation exposures (both absorbed dose and biologically relevant dose equivalent), and a count of the

  1. Radiation in Particle Simulations

    SciTech Connect

    More, R M; Graziani, F R; Glosli, J; Surh, M

    2009-06-15

    Hot dense radiative (HDR) plasmas common to Inertial Confinement Fusion (ICF) and stellar interiors have high temperature (a few hundred eV to tens of keV), high density (tens to hundreds of g/cc) and high pressure (hundreds of Megabars to thousands of Gigabars). Typically, such plasmas undergo collisional, radiative, atomic and possibly thermonuclear processes. In order to describe HDR plasmas, computational physicists in ICF and astrophysics use atomic-scale microphysical models implemented in various simulation codes. Experimental validation of the models used to describe HDR plasmas are difficult to perform. Direct Numerical Simulation (DNS) of the many-body interactions of plasmas is a promising approach to model validation but, previous work either relies on the collisionless approximation or ignores radiation. We present four methods that attempt a new numerical simulation technique to address a currently unsolved problem: the extension of molecular dynamics to collisional plasmas including emission and absorption of radiation. The first method applies the Lienard-Weichert solution of Maxwell's equations for a classical particle whose motion is assumed to be known (section 3). The second method expands the electromagnetic field in normal modes (plane-waves in a box with periodic boundary-conditions) and solves the equation for wave amplitudes coupled to the particle motion (section 4). The third method is a hybrid MD/MC (molecular dynamics/Monte Carlo) method which calculates radiation emitted or absorbed by electron-ion pairs during close collisions (section 5). The fourth method is a generalization of the third method to include small clusters of particles emitting radiation during close encounters: one electron simultaneously hitting two ions, two electrons simultaneously hitting one ion, etc.(section 6). This approach is inspired by the Virial expansion method of equilibrium statistical mechanics.

  2. Radiation Hazard Detector

    NASA Technical Reports Server (NTRS)

    1978-01-01

    NASA technology has made commercially available a new, inexpensive, conveniently-carried device for protection, of people exposed to potentially dangerous levels of microwave radiation. Microwaves are radio emissions of extremely high frequency. They can be hazardous but the degree of hazard is not yet well understood. Generally, it is believed that low intensity radiation of short duration is not harmful but that exposure to high levels can induce deep internal burns, affecting the circulatory and nervous systems, and particularly the eyes. The Department of Labor's Occupational Safety and Health Administration (OSHA) has established an allowable safe threshold of exposure. However, people working near high intensity sources of microwave energy-for example, radar antennas and television transmitters-may be unknowingly exposed to radiation levels beyond the safe limit. This poses not only a personal safety problem but also a problem for employers in terms of productivity loss, workman's compensation claims and possible liability litigation. Earlier-developed monitoring devices which warn personnel of dangerous radiation levels have their shortcomings. They can be cumbersome and awkward to use while working. They also require continual visual monitoring to determine if a person is in a dangerous area of radiation, and they are relatively expensive, another deterrent to their widespread adoption. In response to the need for a cheaper and more effective warning system, Jet Propulsion Laboratory developed, under NASA auspices, a new, battery-powered Microwave Radiation Hazard Detector. To bring the product to the commercial market, California Institute Research Foundation, the patent holder, granted an exclusive license to Cicoil Corporation, Chatsworth, California, an electronic components manufacturer.

  3. Saturn Radiation (SATRAD) Model

    NASA Technical Reports Server (NTRS)

    Garrett, H. B.; Ratliff, J. M.; Evans, R. W.

    2005-01-01

    The Saturnian radiation belts have not received as much attention as the Jovian radiation belts because they are not nearly as intense-the famous Saturnian particle rings tend to deplete the belts near where their peak would occur. As a result, there has not been a systematic development of engineering models of the Saturnian radiation environment for mission design. A primary exception is that of Divine (1990). That study used published data from several charged particle experiments aboard the Pioneer 1 1, Voyager 1, and Voyager 2 spacecraft during their flybys at Saturn to generate numerical models for the electron and proton radiation belts between 2.3 and 13 Saturn radii. The Divine Saturn radiation model described the electron distributions at energies between 0.04 and 10 MeV and the proton distributions at energies between 0.14 and 80 MeV. The model was intended to predict particle intensity, flux, and fluence for the Cassini orbiter. Divine carried out hand calculations using the model but never formally developed a computer program that could be used for general mission analyses. This report seeks to fill that void by formally developing a FORTRAN version of the model that can be used as a computer design tool for missions to Saturn that require estimates of the radiation environment around the planet. The results of that effort and the program listings are presented here along with comparisons with the original estimates carried out by Divine. In addition, Pioneer and Voyager data were scanned in from the original references and compared with the FORTRAN model s predictions. The results were statistically analyzed in a manner consistent with Divine s approach to provide estimates of the ability of the model to reproduce the original data. Results of a formal review of the model by a panel of experts are also presented. Their recommendations for further tests, analyses, and extensions to the model are discussed.

  4. Radar frequency radiation

    NASA Astrophysics Data System (ADS)

    Malowicki, E.

    1981-11-01

    A method is presented for the determination of radar frequency radiation power densities that the PAVE PAWS radar system could produce in its air and ground environment. The effort was prompted by the concern of the people in the vicinity of OTIS AFB MA and BEALE AFB CA about the possible radar frequency radiation hazard of the PAVE PAWS radar. The method is based on the following main assumptions that: (a) the total field can be computed as the vector summation of the individual fields due to each antenna element; (b) the individual field can be calculated using distances for which the field point is in the far field of the antenna element. An RFR computer program was coded for the RADC HE 6180 digital computer and exercised to calculate the radiation levels in the air and ground space for the present baseline and the possible Six DB and 10 DB growth systems of the PAVE PAWS radar system at OTIS AFB MA. The average radiation levels due to the surveillance fence were computed for three regions: in the air space in front of the radar, at the radar hazard fence at OTIS AFB MA and at representative ground points in the OTIS AFB vicinity. It was concluded that the radar frequency radiation of PAVE PAWS does not present a hazard to personnel provided there is no entry to the air hazard zone or to the area within the hazard fence. The method developed offers a cost effective way to determine radiation levels from a phased array radar especially in the near field and transition regions.

  5. Thermal radiative properties: Coatings.

    NASA Technical Reports Server (NTRS)

    Touloukian, Y. S.; Dewitt, D. P.; Hernicz, R. S.

    1972-01-01

    This volume consists, for the most part, of a presentation of numerical data compiled over the years in a most comprehensive manner on coatings for all applications, in particular, thermal control. After a moderately detailed discussion of the theoretical nature of the thermal radiative properties of coatings, together with an overview of predictive procedures and recognized experimental techniques, extensive numerical data on the thermal radiative properties of pigmented, contact, and conversion coatings are presented. These data cover metallic and nonmetallic pigmented coatings, enamels, metallic and nonmetallic contact coatings, antireflection coatings, resin coatings, metallic black coatings, and anodized and oxidized conversion coatings.

  6. Solar cell radiation handbook

    NASA Technical Reports Server (NTRS)

    Tada, H. Y.; Carter, J. R., Jr.

    1977-01-01

    Solar cell theory cells are manufactured, and how they are modeled mathematically is reviewed. The interaction of energetic charged particle radiation with solar cells is discussed in detail and the concept of 1 MeV equivalent electron fluence is introduced. The space radiation environment is described and methods of calculating equivalent fluences for the space environment are developed. A computer program was written to perform the equivalent fluence calculations and a FORTRAN listing of the program is included. Finally, an extensive body of data detailing the degradation of solar cell electrical parameters as a function of 1 MeV electron fluence is presented.

  7. LDEF Satellite Radiation Analyses

    NASA Technical Reports Server (NTRS)

    Armstrong, T. W.; Colborn, B. L.

    1996-01-01

    Model calculations and analyses have been carried out to compare with several sets of data (dose, induced radioactivity in various experiment samples and spacecraft components, fission foil measurements, and LET spectra) from passive radiation dosimetry on the Long Duration Exposure Facility (LDEF) satellite, which was recovered after almost six years in space. The calculations and data comparisons are used to estimate the accuracy of current models and methods for predicting the ionizing radiation environment in low earth orbit. The emphasis is on checking the accuracy of trapped proton flux and anisotropy models.

  8. Radiation ageing of polymers

    NASA Astrophysics Data System (ADS)

    Bartoníček, B.; Hnát, V.; Plaček, V.

    1999-01-01

    Radiation effects on polymers in the presence of air are characterized by dose rate effects and at enhanced temperature by synergistic effects of temperature and radiation. For a reliable simulation of long-term ageing of polymers, conditions for the homogeneous radiooxidation have to be reached. The dose rate values, at which the homogeneous oxidation of irradiated EPR/EVA plates of various thicknesses occurs throughout the sample interior, have been determined. The methodology for the lifetime assessment of cable polymeric materials on the base of the oxidation induction time determination is described.

  9. Radiative decays at LHCb

    NASA Astrophysics Data System (ADS)

    Giubega, L. E.

    2016-12-01

    Precise measurements on rare radiative B decays are performed with the LHCb experiment at LHC. The LHCb results regarding the ratio of branching fractions for two radiative decays, B 0 → K *0 γ and B s → ϕ γ, the direct CP asymmetry in B 0 → K *0 γ decay channel and the observation of the photon polarization in the B ± → K ±π∓π± γ decay, are included. The first two measurements were performed in 1 fb-1 of pp collisions data and the third one in 3 fb-1 of data, respectively.

  10. Radiation Detectors and Art

    NASA Astrophysics Data System (ADS)

    Denker, Andrea

    The use of radiation detectors in the analysis of art objects represents a very special application in a true interdisciplinary field. Radiation detectors employed in this field detect, e.g., x-rays, γ-rays, β particles, and protons. Analyzed materials range from stones, metals, over porcelain to paintings. The available nondestructive and noninvasive analytical methods cover a broad range of techniques. Hence, for the sake of brevity, this chapter will concentrate on few techniques: Proton Induced X-ray Emission (PIXE) and Proton Induced γ-ray Emission (PIGE).

  11. Radiation monitor for liquids

    DOEpatents

    Koster, James E.; Bolton, Richard D.

    1999-01-01

    A radiation monitor for use with liquids that utilizes air ions created by alpha radiation emitted by the liquids as its detectable element. A signal plane, held at an electrical potential with respect to ground, collects these air ions. A guard plane or guard rings is used to limit leakage currents. In one embodiment, the monitor is used for monitoring liquids retained in a tank. Other embodiments monitor liquids flowing through a tank, and bodies of liquids, such as ponds, lakes, rivers and oceans.

  12. Radiation monitor for liquids

    DOEpatents

    Koster, J.E.; Bolton, R.D.

    1999-03-02

    A radiation monitor for use with liquids that utilizes air ions created by alpha radiation emitted by the liquids as its detectable element. A signal plane, held at an electrical potential with respect to ground, collects these air ions. A guard plane or guard rings is used to limit leakage currents. In one embodiment, the monitor is used for monitoring liquids retained in a tank. Other embodiments monitor liquids flowing through a tank, and bodies of liquids, such as ponds, lakes, rivers and oceans. 4 figs.

  13. Radiative plateau inflation

    NASA Astrophysics Data System (ADS)

    Ballesteros, Guillermo; Tamarit, Carlos

    2016-02-01

    We describe how monomial chaotic inflation becomes compatible with the latest CMB data thanks to radiative corrections producing a plateau. The interactions of the inflaton with other fields, required for reheating, can flatten the potential and moderate the production of primordial gravitational waves, keeping these below the current upper bound. We show that the appearance of a plateau requires that the inflaton couples to fermions and to another scalar or a gauge group. We give concrete examples of minimal particle physics models leading to plateaus for quadratic and quartic chaotic inflation. We also provide a three-parameter model-independent description of radiatively corrected inflation that is amenable to CMB analyses.

  14. Wireless passive radiation sensor

    DOEpatents

    Pfeifer, Kent B; Rumpf, Arthur N; Yelton, William G; Limmer, Steven J

    2013-12-03

    A novel measurement technique is employed using surface acoustic wave (SAW) devices, passive RF, and radiation-sensitive films to provide a wireless passive radiation sensor that requires no batteries, outside wiring, or regular maintenance. The sensor is small (<1 cm.sup.2), physically robust, and will operate unattended for decades. In addition, the sensor can be insensitive to measurement position and read distance due to a novel self-referencing technique eliminating the need to measure absolute responses that are dependent on RF transmitter location and power.

  15. Radiation Monitoring Equipment Dosimeter Experiment

    NASA Technical Reports Server (NTRS)

    Hardy, Kenneth A.; Golightly, Michael J.; Quam, William

    1992-01-01

    Spacecraft crews risk exposure to relatively high levels of ionizing radiation. This radiation may come from charged particles trapped in the Earth's magnetic fields, charged particles released by solar flare activity, galactic cosmic radiation, energetic photons and neutrons generated by interaction of these primary radiations with spacecraft and crew, and man-made sources (e.g., nuclear power generators). As missions are directed to higher radiation level orbits, viz., higher altitudes and inclinations, longer durations, and increased flight frequency, radiation exposure could well become a major factor for crew stay time and career lengths. To more accurately define the radiological exposure and risk to the crew, real-time radiation monitoring instrumentation, which is capable of identifying and measuring the various radiation components, must be flown. This presentation describes a radiation dosimeter instrument which was successfully flown on the Space Shuttle, the RME-3.

  16. Space Radiation and the Brain

    NASA Astrophysics Data System (ADS)

    Hampson, R. E.

    Solar and cosmic radiation pose a number of physiological challenges to human spaceflight outside the protective region of Earth's magnetosphere. Aside from well-described effects of radiation on the blood-forming tissues of the hematopoietic system, there is increasing evidence of direct effects of radiation on the brain as evidenced by studies showing longitudinal decline in memory and cognitive function following radiation specifically directed at brain tissue. These indications strengthen the need to more fully research effects of radiation - particular those components associated with solar wind and galactic cosmic radiation - on the nervous system of mammals from rodents to humans.

  17. Radiation Safety in Pediatric Orthopaedics.

    PubMed

    Caird, Michelle S

    2015-01-01

    Patients, surgeons, and staff are exposed to ionizing radiation in pediatric orthopaedic surgery from diagnostic studies and imaging associated with procedures. Estimating radiation dose to pediatric patients is based on complex algorithms and dose to surgeons and staff is based on dosimeter monitoring. Surgeons can decrease radiation exposure to patients with careful and thoughtful ordering of diagnostic studies and by minimizing exposure intraoperatively. Surgeon and staff radiation exposure can be minimized with educational programs, proper shielding and positioning intraoperatively, and prudent use of intraoperative imaging. Overall, better awareness among pediatric orthopaedic surgeons of our role in radiation exposure can lead to improvements in radiation safety.

  18. Paradoxes of Thermal Radiation

    ERIC Educational Resources Information Center

    Besson, U.

    2009-01-01

    This paper presents an analysis of the thermal behaviour of objects exposed to a solar-type flux of thermal radiation. It aims to clarify certain apparent inconsistencies between theory and observation, and to give a detailed exposition of some critical points that physics textbooks usually treat in an insufficient or incorrect way. In particular,…

  19. Radiative accidental matter

    NASA Astrophysics Data System (ADS)

    Sierra, D. Aristizabal; Simoes, C.; Wegman, D.

    2016-07-01

    Accidental matter models are scenarios where the beyond-the-standard model physics preserves all the standard model accidental and approximate symmetries up to a cutoff scale related with lepton number violation. We study such scenarios assuming that the new physics plays an active role in neutrino mass generation, and show that this unavoidably leads to radiatively induced neutrino masses. We systematically classify all possible models and determine their viability by studying electroweak precision data, big bang nucleosynthesis and electroweak perturbativity, finding that the latter places the most stringent constraints on the mass spectra. These results allow the identification of minimal radiative accidental matter models for which perturbativity is lost at high scales. We calculate radiative charged-lepton flavor violating processes in these setups, and show that μ → eγ has a rate well within MEG sensitivity provided the lepton-number violating scale is at or below 5×105 GeV, a value (naturally) assured by the radiative suppression mechanism. Sizeable τ → μγ branching fractions within SuperKEKB sensitivity are possible for lower lepton-number breaking scales. We thus point out that these scenarios can be tested not only in direct searches but also in lepton flavor-violating experiments.

  20. Radiation detector spectrum simulator

    DOEpatents

    Wolf, M.A.; Crowell, J.M.

    1985-04-09

    A small battery operated nuclear spectrum simulator having a noise source generates pulses with a Gaussian distribution of amplitudes. A switched dc bias circuit cooperating therewith to generate several nominal amplitudes of such pulses and a spectral distribution of pulses that closely simulates the spectrum produced by a radiation source such as Americium 241.

  1. Radiation detector spectrum simulator

    DOEpatents

    Wolf, Michael A.; Crowell, John M.

    1987-01-01

    A small battery operated nuclear spectrum simulator having a noise source nerates pulses with a Gaussian distribution of amplitudes. A switched dc bias circuit cooperating therewith generates several nominal amplitudes of such pulses and a spectral distribution of pulses that closely simulates the spectrum produced by a radiation source such as Americium 241.

  2. Surface Radiation Budget

    NASA Technical Reports Server (NTRS)

    Stackhouse, Paul W. (Principal Investigator)

    The Surface Radiation Budget (SRB) data sets contain global 3-hourly, daily and monthly averages of surface longwave and shortwave radiative properties, cloud amount, and meteorological properties computed using models. The main input data for these models include cloud information, top-of-atmosphere radiances and profiles of atmospheric water vapor and temperature. Some of the input data include Earth Radiation Budget Energy (ERBE) top-of-atmosphere clear-sky albedo and International Satellite Cloud Climatology Project (ISCCP) radiances and cloud amount. SRB parameters derived for the renewable energy community are also available from the Surface meteorology and Solar Energy (SSE) data set. Other SRB data are available from Clouds and the Earth's Radiant Energy System (CERES) and Multi-angle Imaging SpectroRadiometer (MISR). [Mission Objectives] The objective of the SRB Project is to produce and archive a global data set of shortwave (SW) and longwave (LW) surface and top of the atmosphere parameters. The data generated in the SRB project may be used in conjunction with other data sets to facilitate the development of renewable energy resources and increase understanding of radiative properties within the meteorological community. [Temporal_Coverage: Start_Date=1983-07-01; Stop_Date=2005-06-30] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180].

  3. Radiation belts of jupiter.

    PubMed

    Fillius, R W; McIlwain, C E

    1974-01-25

    Pioneer 10 counted relativistic electrons throughout the magnetosphere of Jupiter, with the greatest fluxes being inside 20 Jupiter radii. The peak flux of electrons with energy greater than 50 million electron volts was 1.3 x 10(7) per square centimeter per second at the innermost penetration of the radiation belts.

  4. An Inexpensive Radiation Counter.

    ERIC Educational Resources Information Center

    Holton, Brian; Balla, Zsolt

    1985-01-01

    Describes a radiation counter comparable to commercial units which costs less than $100. It consists of six sections: Geiger-Mueller tube and holder; high voltage supply; low voltage supply; pulse shaping circuit; "start/stop counts" gating circuit; and counter/display. List of materials needed and schematic diagrams are included. (JN)

  5. Continuum radiation at Uranus

    SciTech Connect

    Kurth, W.S.; Gurnett, D.A. ); Desch, M.D. )

    1990-02-01

    Uranus has proven to be a radio source of remarkable complexity with as many as six distinctly different types of emission. One Uranian radio emission which has thus far escaped attention is an analog of continuum radiation at Earth, Jupiter, and Saturn. The emission is found to be propagating in the ordinary mode in the range of one to a few kHz on the inbound leg of the Voyager 2 encounter, shortly after the magnetopause crossing. The continuum radiation spectrum at Uranus also includes bands with frequencies as high as 12 kHz or greater on both the inbound and outbound legs. The Uranian continuum radiation is notably weak, making it more like that detected at Saturn than the extremely intense Jovian continuum radiation. The Uranian emission shows some evidence for narrow-band components lying in the same frequency regime as the continuum, completing the analogy with the other planets, which also show narrow-band components superimposed on the continuum spectrum. The authors argue that the low intensity of the Uranian continuum is most likely related to the lack of a density cavity within the Uranian magnetosphere that is deep relative to the solar wind plasma density.

  6. Thermostatic Radiator Valve Evaluation

    SciTech Connect

    Dentz, Jordan; Ansanelli, Eric

    2015-01-01

    A large stock of multifamily buildings in the Northeast and Midwest are heated by steam distribution systems. Losses from these systems are typically high and a significant number of apartments are overheated much of the time. Thermostatically controlled radiator valves (TRVs) are one potential strategy to combat this problem, but have not been widely accepted by the residential retrofit market.

  7. Radiation Hardening of Computers

    NASA Technical Reports Server (NTRS)

    Nichols, D. K.; Smith, L. S.; Zoutendyk, J. A.; Giddings, A. E.; Hewlett, F. W.; Treece, R. K.

    1986-01-01

    Single-event upsets reduced by use of oversize transistors. Computers made less susceptible to ionizing radiation by replacing bipolar integrated circuits with properly designed, complementary metaloxide-semiconductor (CMOS) circuits. CMOS circuit chips made highly resistant to single-event upset (SEU), especially when certain feedback resistors are incorporated. Redesigned chips also consume less power than original chips.

  8. Modeling Radiation Fog

    NASA Astrophysics Data System (ADS)

    K R, Sreenivas; Mohammad, Rafiuddin

    2016-11-01

    Predicting the fog-onset, its growth and dissipation helps in managing airports and other modes of transport. After sunset, occurrence of fog requires moist air, low wind and clear-sky conditions. Under these circumstances radiative heat transfer plays a vital role in the NBL. Locally, initiation of fog happens when the air temperature falls below the dew-point. Thus, to predict the onset of fog at a given location, one has to compute evolution of vertical temperature profile. Earlier,our group has shown that the presence of aerosols and vertical variation in their number density determines the radiative-cooling and hence development of vertical temperature profile. Aerosols, through radiation in the window-band, provides an efficient path for air layers to lose heat to the cold, upper atmosphere. This process creates cooler air layer between warmer ground and upper air layers and resulting temperature profile facilitate the initiation of fog. Our results clearly indicates that accounting for the presence of aerosols and their radiative-transfer is important in modeling micro-meteorological process of fog formation and its evolution. DST, Govt. INDIA.

  9. Ionizing radiation from tobacco

    SciTech Connect

    Westin, J.B.

    1987-04-24

    Accidents at nuclear power facilities seem inevitably to bring in their wake a great deal of concern on the part of both the lay and medical communities. Relatively little attention, however, is given to what may be the largest single worldwide source of effectively carcinogenic ionizing radiation: tobacco. The risk of cancer deaths from the Chernobyl disaster are tobacco smoke is discussed.

  10. Radiation injury of bone

    SciTech Connect

    Shimanovskaya, K.; Shiman, A.D.

    1983-01-01

    This monograph is devoted to the characteristics of radiation injuries arising in hitherto unaffected parts of the skeleton during the treatment of neoplasms by radiotherapy. These changes frequently accompany the beneficial effects of radiotherapy, and can easily be misunderstood in the absence of any clear idea of their character. An understanding of the mechanism and conditions of appearance of radiation injuries of the skeleton and a knowledge of their clinical and radiological features are essential for physicians and surgeons caring for patients who have been treated by using radiotherapy and for experimental scientists whose work involves such methods. The effect of irradiation is determined by the topographical relations within the irradiated object, the character of distribution of the dose, and the size of the dose. The radiation injuries of the skeleton described in the book were observed during the treatment of carcinoma of the breast, lung, esophagus, and uterus, of malignant tumors in the mouth, certain pituitary tumors, and hemangiomas of the skin in children, by means of ionizing radiation obtained from various sources. A few observations relate to patients treated for certain other diseases. The text is illustrated by roentgenograms on the basis of which the diagnoses were made and the course of the lesion was subsequently confirmed, and also by operative and histological specimens. The book also contains many schemes drawn from roentgenograms.

  11. Psoriasis and ultraviolet radiation

    SciTech Connect

    Farber, E.M.; Nall, L. )

    1993-09-01

    Prevention and detection screening programs as a public health service in curtailing the ever-increasing incidence of all forms of skin cancer are reviewed. The effect of solar and artificial ultraviolet radiation on the general population and persons with psoriasis is examined. 54 refs.

  12. Manifolds and Radiation Protection

    NASA Astrophysics Data System (ADS)

    Rossitto, Franco; Petrov, Vladislav M.; Ongaro, Filippo

    During the past 40 years humans have travelled beyond Earth's atmosphere, orbiting the planets for extended periods of time and landing on the Moon. Humans have survived this overwhelming challenge but to assure future exploration of space further expertise in the long term survival in space must be obtained. The International Space Station (ISS) provides this opportunity and allows space scientist to fine-tune their knowledge and prepare for even bolder human space missions. In this work we focus on the aspect of radiation, perhaps the most complex one from a physical and physiological perspective. Travel beyond the Earth's atmosphere and especially to Moon and Mars requires a precise consideration of the radiation environment as radiation exposure could be a show-stopper. At the moment scientists have not yet developed complete and reliable systems for radiation protection. Most likely an adequate level of protection will be reached through an integrated countermeasure system which could include: shields, monitoring of the environment, drugs to protect from damage, etc.

  13. Photovoltaic radiation detector element

    DOEpatents

    Agouridis, Dimitrios C.

    1983-01-01

    A radiation detector element is formed of a body of semiconductor material, a coating on the body which forms a photovoltaic junction therewith, and a current collector consisting of narrow metallic strips, the aforesaid coating having an opening therein the edge of which closely approaches but is spaced from the current collector strips.

  14. Optical electromagnetic radiation detector

    NASA Astrophysics Data System (ADS)

    Miceli, W. J.; Ludman, J. E.

    1985-08-01

    An optical electromagnetic radiation detector is invented having a probe for receiving nearby electromagnetic radiation. The probe includes a loop antenna connected to a pair of transparent electrodes deposited on the end surfaces of an electro-optic Fabry-Perot interferometer. When the loop antenna picks up the presence of electromagnetic radiation, a voltage will be developed across the crystal of the electro-optic Fabry-Perot interferometer thereby changing the optical length of the interferometer. A beam of light from a remote location is transmitted through an optical fiber onto the Fabry-Perot interferometer. The change in optical length of the Fabry-Perot interferometer alters the intensity of the beam of light as its is reflected from the Fabry-Perot interferometer back through the optical fiber to the remote location. A beamsplitter directs this reflected beam of light onto an intensity detector in order to provide an output indicative of the variations in intensity. The variations in intensity are directly related to the strength of the electromagnetic radiation received by the loop antenna.

  15. VDT Emissions Radiate Debate.

    ERIC Educational Resources Information Center

    Morgan, Bill

    1990-01-01

    Discusses the possible health effects of electromagnetic fields of radiation that are emitted from video display terminals (VDTs). Responses from vendors in the computer industry are related, steps to reduce possible risks are suggested, and additional sources of information on VDTs are listed. (LRW)

  16. Radiation damping on cryoprobes.

    PubMed

    Shishmarev, Dmitry; Otting, Gottfried

    2011-12-01

    Radiation damping on 600 and 800 MHz cryoprobes was investigated. The phase angle β between a vector 90° phase shifted to the precessing magnetization and the rf field induced in the coil was found to depend markedly on whether an FID was being acquired or not. The magnitude of the radiation damping field was sufficiently strong to restore 95% of the equilibrium water magnetization of a 90% H2O sample in a 5 mm sample tube within about 5 ms following a 165° pulse. This can be exploited in water flip-back versions of NOESY and TOCSY experiments of proteins, but care must be taken to limit the effect of the radiation damping field from the water on the Ha protons. Long water-selective pulses can be applied only following corrections. We developed a program for correcting pulse shapes if β is non-zero. The WATERGATE scheme is shown to be insensitive to imperfections introduced by radiation damping.

  17. Thermodynamics of Radiation Modes

    ERIC Educational Resources Information Center

    Pina, Eduardo; de la Selva, Sara Maria Teresa

    2010-01-01

    We study the equilibrium thermodynamics of the electromagnetic radiation in a cavity of a given volume and temperature. We found three levels of description, the thermodynamics of one mode, the thermodynamics of the distribution of frequencies in a band by summing over the frequencies in it and the global thermodynamics by summing over all the…

  18. Radiations from hot nuclei

    NASA Technical Reports Server (NTRS)

    Malik, F. Bary

    1993-01-01

    The investigation indicates that nuclei with excitation energy of a few hundred MeV to BeV are more likely to radiate hot nuclear clusters than neutrons. These daughter clusters could, furthermore, de-excite emitting other hot nuclei, and the chain continues until these nuclei cool off sufficiently to evaporate primarily neutrons. A few GeV excited nuclei could radiate elementary particles preferentially over neutrons. Impact of space radiation with materials (for example, spacecraft) produces highly excited nuclei which cool down emitting electromagnetic and particle radiations. At a few MeV excitation energy, neutron emission becomes more dominant than gamma-ray emission and one often attributes the cooling to take place by successive neutron decay. However, a recent experiment studying the cooling process of 396 MeV excited Hg-190 casts some doubt on this thinking, and the purpose of this investigation is to explore the possibility of other types of nuclear emission which might out-compete with neutron evaporation.

  19. Acute radiation risk models

    NASA Astrophysics Data System (ADS)

    Smirnova, Olga

    Biologically motivated mathematical models, which describe the dynamics of the major hematopoietic lineages (the thrombocytopoietic, lymphocytopoietic, granulocytopoietic, and erythropoietic systems) in acutely/chronically irradiated humans are developed. These models are implemented as systems of nonlinear differential equations, which variables and constant parameters have clear biological meaning. It is shown that the developed models are capable of reproducing clinical data on the dynamics of these systems in humans exposed to acute radiation in the result of incidents and accidents, as well as in humans exposed to low-level chronic radiation. Moreover, the averaged value of the "lethal" dose rates of chronic irradiation evaluated within models of these four major hematopoietic lineages coincides with the real minimal dose rate of lethal chronic irradiation. The demonstrated ability of the models of the human thrombocytopoietic, lymphocytopoietic, granulocytopoietic, and erythropoietic systems to predict the dynamical response of these systems to acute/chronic irradiation in wide ranges of doses and dose rates implies that these mathematical models form an universal tool for the investigation and prediction of the dynamics of the major human hematopoietic lineages for a vast pattern of irradiation scenarios. In particular, these models could be applied for the radiation risk assessment for health of astronauts exposed to space radiation during long-term space missions, such as voyages to Mars or Lunar colonies, as well as for health of people exposed to acute/chronic irradiation due to environmental radiological events.

  20. Nuclear Radiation Damages Minds!

    ERIC Educational Resources Information Center

    Blai, Boris, Jr.

    Professors Ernest Sternglass (University of Pittsburgh) and Steven Bell (Berry College) have assembled cogent, conclusive evidence indicating that nuclear radiation is associated with impaired cognition. They suggest that Scholastic Aptitude Scores (SATs), which have declined steadily for 19 years, will begin to rise. Their prediction is based on…

  1. Radiation Source Replacement Workshop

    SciTech Connect

    Griffin, Jeffrey W.; Moran, Traci L.; Bond, Leonard J.

    2010-12-01

    This report summarizes a Radiation Source Replacement Workshop in Houston Texas on October 27-28, 2010, which provided a forum for industry and researchers to exchange information and to discuss the issues relating to replacement of AmBe, and potentially other isotope sources used in well logging.

  2. [Radiation protection agents to provide the radiation safety of astronauts].

    PubMed

    Ushakov, I B; Ivanov, A A

    2013-01-01

    Taking into consideration the complexity of radiation factors and stressogenic factors of non-radiation nature in cosmic flights and prognostic difficulties of radiation situation, the authors propose to distinguish several stages of pharmacological protection for cosmonauts. The preparatory stage is realized on the Earth. The next stage is monitoring and correction of radioresistance during a flight. A possible stage consists of treatment of the radiation damage using a traditional protocol. The permanent stage includes pharmacological prevention of the distant consequences of irradiation.

  3. Radiation proteomics: a brief overview.

    PubMed

    Leszczynski, Dariusz

    2014-03-01

    Acute biological effects caused by the exposure to high doses of radiation, either ionizing or nonionizing, are relatively well-known but the delayed effects, occurring decades after exposure, are difficult to predict. The knowledge of the acute and delayed effects of the low doses of ionizing radiation (e.g. bystander effect) or nonionizing radiation (e.g. radiation emitted by wireless communication devices) is not yet reliably established. Often the acute effects of low doses are small and difficult to discover and replicate in scientific studies. Chronic effects of prolonged exposures to low-dose radiation for decades are virtually unknown and often not possible to predict on the basis of the knowledge gained from acute exposures to high doses of radiation. Physiological significance of the biological effects induced by low doses of radiation is not known. The same lack of predictability of outcomes applies to the delayed effects of high-dose radiation exposures. Proteomics, supplemented with other "omics" techniques, might be the best way forward to find out the target molecules of radiation, the biomarkers of radiation exposure and the physiological and health significance of the acute and delayed biological effects caused by the exposures to high- and low-dose radiation. However, the currently available database of radiation effects on proteomes is far too small to be useful in formulation of new hypotheses concerning health consequences of radiation exposures.

  4. SSC environmental radiation shielding

    SciTech Connect

    Jackson, J.D.

    1987-07-01

    The environmental radiation shielding requirements of the SSC have been evaluated using currently available computational tools that incorporate the well known processes of energy loss and degradation of high energy particles into Monte Carlo computer codes. These tools permit determination of isodose contours in the matter surrounding a source point and therefore the specification of minimum thicknesses or extents of shielding in order to assure annual dose equivalents less than some specified design amount. For the general public the annual dose equivalent specified in the design is 10 millirem, small compared to the dose from naturally occurring radiation. The types of radiation fall into two classes for the purposes of shielding determinations-hadrons and muons. The sources of radiation at the SSC of concern for the surrounding environment are the interaction regions, the specially designed beam dumps into which the beams are dumped from time to time, and beam clean-up regions where stops remove the beam halo in order to reduce experimental backgrounds. A final, unlikely source of radiation considered is the accidental loss of the full beam at some point around the ring. Conservative choices of a luminosity of 10{sup 34} cm{sup {minus}2}s{sup {minus}1} and a beam current three times design have been made in calculating the required shielding and boundaries of the facility. In addition to determination of minimum distances for the annual dose equivalents, the question of possible radioactivity produced in nearby wells or in municipal water supplies is addressed. The designed shielding distances and beam dumps are such that the induced radioactivity in ground water is safely smaller than the levels permitted by EPA and international agencies.

  5. Spacecraft Electrostatic Radiation Shielding

    NASA Technical Reports Server (NTRS)

    2008-01-01

    This project analyzed the feasibility of placing an electrostatic field around a spacecraft to provide a shield against radiation. The concept was originally proposed in the 1960s and tested on a spacecraft by the Soviet Union in the 1970s. Such tests and analyses showed that this concept is not only feasible but operational. The problem though is that most of this work was aimed at protection from 10- to 100-MeV radiation. We now appreciate that the real problem is 1- to 2-GeV radiation. So, the question is one of scaling, in both energy and size. Can electrostatic shielding be made to work at these high energy levels and can it protect an entire vehicle? After significant analysis and consideration, an electrostatic shield configuration was proposed. The selected architecture was a torus, charged to a high negative voltage, surrounding the vehicle, and a set of positively charged spheres. Van de Graaff generators were proposed as the mechanism to move charge from the vehicle to the torus to generate the fields necessary to protect the spacecraft. This design minimized complexity, residual charge, and structural forces and resolved several concerns raised during the internal critical review. But, it still is not clear if such a system is costeffective or feasible, even though several studies have indicated usefulness for radiation protection at energies lower than that of the galactic cosmic rays. Constructing such a system will require power supplies that can generate voltages 10 times that of the state of the art. Of more concern is the difficulty of maintaining the proper net charge on the entire structure and ensuring that its interaction with solar wind will not cause rapid discharge. Yet, if these concerns can be resolved, such a scheme may provide significant radiation shielding to future vehicles, without the excessive weight or complexity of other active shielding techniques.

  6. Apparatus for generating partially coherent radiation

    DOEpatents

    Naulleau, Patrick P.

    2005-02-22

    Techniques for generating partially coherent radiation and particularly for converting effectively coherent radiation from a synchrotron to partially coherent EUV radiation suitable for projection lithography.

  7. The Radiation Belt Storm Probes

    NASA Video Gallery

    The Radiation Belt Storm Probe mission (RBSP) will explore the Van Allen Radiation Belts in the Earth's magnetosphere. The charge particles in these regions can be hazardous to both spacecraft and ...

  8. American Society for Radiation Oncology

    MedlinePlus

    ... I AM A: Please Select a User Type Radiation Oncologist Medical Physicist Researcher Member of Treatment Team ... award/grant Please Select an Action Find a radiation oncologist Learn more about RT for breast cancer ...

  9. Hawking radiation and covariant anomalies

    SciTech Connect

    Banerjee, Rabin; Kulkarni, Shailesh

    2008-01-15

    Generalizing the method of Wilczek and collaborators we provide a derivation of Hawking radiation from charged black holes using only covariant gauge and gravitational anomalies. The reliability and universality of the anomaly cancellation approach to Hawking radiation is also discussed.

  10. Radiative Forcing of Climate Change

    SciTech Connect

    Ramaswamy, V.; Boucher, Olivier; Haigh, J.; Hauglustaine, D.; Haywood, J.; Myhre, G.; Nakajima, Takahito; Shi, Guangyu; Solomon, S.; Betts, Robert E.; Charlson, R.; Chuang, C. C.; Daniel, J. S.; Del Genio, Anthony D.; Feichter, J.; Fuglestvedt, J.; Forster, P. M.; Ghan, Steven J.; Jones, A.; Kiehl, J. T.; Koch, D.; Land, C.; Lean, J.; Lohmann, Ulrike; Minschwaner, K.; Penner, Joyce E.; Roberts, D. L.; Rodhe, H.; Roelofs, G.-J.; Rotstayn, Leon D.; Schneider, T. L.; Schumann, U.; Schwartz, Stephen E.; Schwartzkopf, M. D.; Shine, K. P.; Smith, Steven J.; Stevenson, D. S.; Stordal, F.; Tegen, I.; van Dorland, R.; Zhang, Y.; Srinivasan, J.; Joos, Fortunat

    2001-10-01

    Chapter 6 of the IPCC Third Assessment Report Climate Change 2001: The Scientific Basis. Sections include: Executive Summary 6.1 Radiative Forcing 6.2 Forcing-Response Relationship 6.3 Well-Mixed Greenhouse Gases 6.4 Stratospheric Ozone 6.5 Radiative Forcing By Tropospheric Ozone 6.6 Indirect Forcings due to Chemistry 6.7 The Direct Radiative Forcing of Tropospheric Aerosols 6.8 The Indirect Radiative Forcing of Tropospheric Aerosols 6.9 Stratospheric Aerosols 6.10 Land-use Change (Surface Albedo Effect) 6.11 Solar Forcing of Climate 6.12 Global Warming Potentials hydrocarbons 6.13 Global Mean Radiative Forcings 6.14 The Geographical Distribution of the Radiative Forcings 6.15 Time Evolution of Radiative Forcings Appendix 6.1 Elements of Radiative Forcing Concept References.

  11. Radiation Injury to the Brain

    MedlinePlus

    ... Hits since January 2003 RADIATION INJURY TO THE BRAIN Radiation treatments affect all cells that are targeted. ... fractions, duration of therapy, and volume of [healthy brain] nervous tissue irradiated influence the likelihood of injury. ...

  12. Conical electromagnetic radiation flux concentrator

    NASA Technical Reports Server (NTRS)

    Miller, E. R.

    1972-01-01

    Concentrator provides method of concentrating a beam of electromagnetic radiation into a smaller beam, presenting a higher flux density. Smaller beam may be made larger by sending radiation through the device in the reverse direction.

  13. Radiation Therapy for Skin Cancer

    MedlinePlus

    ... make sure they are safe to use during radiation therapy. • Eat a balanced diet. If food tastes ... your fluid intake. • Treat the skin exposed to radiation with special care. Stay out of the sun, ...

  14. Radiation Therapy for Lung Cancer

    MedlinePlus

    ... cancer, surgery has been the standard. However, in patients medically not able to tolerate surgery, focused radiation, called stereotactic body radiation therapy (SBRT) is a good treatment option. For large ...

  15. Gamma radiation field intensity meter

    DOEpatents

    Thacker, L.H.

    1994-08-16

    A gamma radiation intensity meter measures dose rate of a radiation field. The gamma radiation intensity meter includes a tritium battery emitting beta rays generating a current which is essentially constant. Dose rate is correlated to an amount of movement of an electroscope element charged by the tritium battery. Ionizing radiation decreases the voltage at the element and causes movement. A bleed resistor is coupled between the electroscope support element or electrode and the ionization chamber wall electrode. 4 figs.

  16. Gamma radiation field intensity meter

    DOEpatents

    Thacker, Louis H.

    1995-01-01

    A gamma radiation intensity meter measures dose rate of a radiation field. The gamma radiation intensity meter includes a tritium battery emitting beta rays generating a current which is essentially constant. Dose rate is correlated to an amount of movement of an electroscope element charged by the tritium battery. Ionizing radiation decreases the voltage at the element and causes movement. A bleed resistor is coupled between the electroscope support element or electrode and the ionization chamber wall electrode.

  17. Gamma radiation field intensity meter

    DOEpatents

    Thacker, Louis H.

    1994-01-01

    A gamma radiation intensity meter measures dose rate of a radiation field. The gamma radiation intensity meter includes a tritium battery emitting beta rays generating a current which is essentially constant. Dose rate is correlated to an amount of movement of an electroscope element charged by the tritium battery. Ionizing radiation decreases the voltage at the element and causes movement. A bleed resistor is coupled between the electroscope support element or electrode and the ionization chamber wall electrode.

  18. Gamma radiation field intensity meter

    SciTech Connect

    Thacker, L.H.

    1995-10-17

    A gamma radiation intensity meter measures dose rate of a radiation field. The gamma radiation intensity meter includes a tritium battery emitting beta rays generating a current which is essentially constant. Dose rate is correlated to an amount of movement of an electroscope element charged by the tritium battery. Ionizing radiation decreases the voltage at the element and causes movement. A bleed resistor is coupled between the electroscope support element or electrode and the ionization chamber wall electrode. 4 figs.

  19. Space Radiation Cancer Risks

    NASA Technical Reports Server (NTRS)

    Cucinotta, Francis A.

    2007-01-01

    Space radiation presents major challenges to astronauts on the International Space Station and for future missions to the Earth s moon or Mars. Methods used to project risks on Earth need to be modified because of the large uncertainties in projecting cancer risks from space radiation, and thus impact safety factors. We describe NASA s unique approach to radiation safety that applies uncertainty based criteria within the occupational health program for astronauts: The two terrestrial criteria of a point estimate of maximum acceptable level of risk and application of the principle of As Low As Reasonably Achievable (ALARA) are supplemented by a third requirement that protects against risk projection uncertainties using the upper 95% confidence level (CL) in the radiation cancer projection model. NASA s acceptable level of risk for ISS and their new lunar program have been set at the point-estimate of a 3-percent risk of exposure induced death (REID). Tissue-averaged organ dose-equivalents are combined with age at exposure and gender-dependent risk coefficients to project the cumulative occupational radiation risks incurred by astronauts. The 95% CL criteria in practice is a stronger criterion than ALARA, but not an absolute cut-off as is applied to a point projection of a 3% REID. We describe the most recent astronaut dose limits, and present a historical review of astronaut organ doses estimates from the Mercury through the current ISS program, and future projections for lunar and Mars missions. NASA s 95% CL criteria is linked to a vibrant ground based radiobiology program investigating the radiobiology of high-energy protons and heavy ions. The near-term goal of research is new knowledge leading to the reduction of uncertainties in projection models. Risk projections involve a product of many biological and physical factors, each of which has a differential range of uncertainty due to lack of data and knowledge. The current model for projecting space radiation

  20. Radiation Effects: Core Project

    NASA Technical Reports Server (NTRS)

    Dicello, John F.

    1999-01-01

    The risks to personnel in space from the naturally occurring radiations are generally considered to be one of the most serious limitations to human space missions, as noted in two recent reports of the National Research Council/National Academy of Sciences. The Core Project of the Radiation Effects Team for the National Space Biomedical Research Institute is the consequences of radiations in space in order to develop countermeasure, both physical and pharmaceutical, to reduce the risks of cancer and other diseases associated with such exposures. During interplanetary missions, personnel in space will be exposed to galactic cosmic rays, including high-energy protons and energetic ions with atomic masses of iron or higher. In addition, solar events will produce radiation fields of high intensity for short but irregular durations. The level of intensity of these radiations is considerably higher than that on Earth's surface, and the biological risks to astronauts is consequently increased, including increased risks of carcinogenesis and other diseases. This group is examining the risk of cancers resulting from low-dose, low-dose rate exposures of model systems to photons, protons, and iron by using ground-based accelerators which are capable of producing beams of protons, iron, and other heavy ions at energies comparable to those encountered in space. They have begun the first series of experiments using a 1-GeV iron beam at the Brookhaven National Laboratory and 250-MeV protons at Loma Linda University Medical Center's proton synchrotron facility. As part of these studies, this group will be investigating the potential for the pharmaceutical, Tamoxifen, to reduce the risk of breast cancer in astronauts exposed to the level of doses and particle types expected in space. Theoretical studies are being carried out in a collaboration between scientists at NASA's Johnson Space Center and Johns Hopkins University in parallel with the experimental program have provided

  1. Pregnancy and Radiation Protection

    SciTech Connect

    Gerogiannis, J.; Stefanoyiannis, A. P.

    2010-01-21

    Several modalities are currently utilized for diagnosis and therapy, by appropriate application of x-rays. In diagnostic radiology, interventional radiology, radiotherapy, interventional cardiology, nuclear medicine and other specialties radiation protection of a pregnant woman as a patient, as well as a member of the operating personnel, is of outmost importance. Based on radiation risk, the termination of pregnancy is not justified if foetal doses are below 100 mGy. For foetal doses between 100 and 500 mGy, a decision is reached on a case by case basis. In Diagnostic Radiology, when a pregnant patient takes an abdomen CT, then an estimation of the foetus' dose is necessary. However, it is extremely rare for the dose to be high enough to justify an abortion. Radiographs of the chest and extremities can be done at any period of pregnancy, provided that the equipment is functioning properly. Usually, the radiation risk is lower than the risk of not undergoing a radiological examination. Radiation exposure in uterus from diagnostic radiological examinations is unlikely to result in any deleterious effect on the child, but the possibility of a radiation-induced effect can not be entirely ruled out. The effects of exposure to radiation on the foetus depend on the time of exposure, the date of conception and the absorbed dose. Finally, a pregnant worker can continue working in an x-ray department, as long as there is reasonable assurance that the foetal dose can be kept below 1 mGy during the pregnancy. Nuclear Medicine diagnostic examinations using short-lived radionuclides can be used for pregnant patient. Irradiation of the foetus results from placental transfer and distribution of radiopharmaceuticals in the foetal tissues, as well as from external irradiation from radioactivity in the mother's organ and tissues. As a rule, a pregnant patient should not undergo therapy with radionuclide, unless it is crucial for her life. In Radiotherapy, the patient, treating

  2. Pregnancy and Radiation Protection

    NASA Astrophysics Data System (ADS)

    Gerogiannis, J.; Stefanoyiannis, A. P.

    2010-01-01

    Several modalities are currently utilized for diagnosis and therapy, by appropriate application of x-rays. In diagnostic radiology, interventional radiology, radiotherapy, interventional cardiology, nuclear medicine and other specialties radiation protection of a pregnant woman as a patient, as well as a member of the operating personnel, is of outmost importance. Based on radiation risk, the termination of pregnancy is not justified if foetal doses are below 100 mGy. For foetal doses between 100 and 500 mGy, a decision is reached on a case by case basis. In Diagnostic Radiology, when a pregnant patient takes an abdomen CT, then an estimation of the foetus' dose is necessary. However, it is extremely rare for the dose to be high enough to justify an abortion. Radiographs of the chest and extremities can be done at any period of pregnancy, provided that the equipment is functioning properly. Usually, the radiation risk is lower than the risk of not undergoing a radiological examination. Radiation exposure in uterus from diagnostic radiological examinations is unlikely to result in any deleterious effect on the child, but the possibility of a radiation-induced effect can not be entirely ruled out. The effects of exposure to radiation on the foetus depend on the time of exposure, the date of conception and the absorbed dose. Finally, a pregnant worker can continue working in an x-ray department, as long as there is reasonable assurance that the foetal dose can be kept below 1 mGy during the pregnancy. Nuclear Medicine diagnostic examinations using short-lived radionuclides can be used for pregnant patient. Irradiation of the foetus results from placental transfer and distribution of radiopharmaceuticals in the foetal tissues, as well as from external irradiation from radioactivity in the mother's organ and tissues. As a rule, a pregnant patient should not undergo therapy with radionuclide, unless it is crucial for her life. In Radiotherapy, the patient, treating

  3. Coherent Radiation of Electron Cloud

    SciTech Connect

    Heifets, S.

    2004-11-02

    The electron cloud in positron storage rings is pinched when a bunch passes by. For short bunches, the radiation due to acceleration of electrons of the cloud is coherent. Detection of such radiation can be used to measure the density of the cloud. The estimate of the power and the time structure of the radiated signal is given in this paper.

  4. Effects Of Radiation On Elastomers

    NASA Technical Reports Server (NTRS)

    Bouquet, Frank L.

    1988-01-01

    Report provides data on effects of radiation on elastomers. Quantifies effects by giving minimum radiation levels to induce changes of 1 percent and 25 percent in given properties. Electrical, mechanical, and chemical properties included in data. Combined effects of heat and radiation briefly considered. Data summarized in graphic form useful to designers.

  5. Video Display Terminals: Radiation Issues.

    ERIC Educational Resources Information Center

    Murray, William E.

    1985-01-01

    Discusses information gathered in past few years related to health effects of video display terminals (VDTs) with particular emphasis given to issues raised by VDT users. Topics covered include radiation emissions, health concerns, radiation surveys, occupational radiation exposure standards, and long-term risks. (17 references) (EJS)

  6. Radiation effect on implanted pacemakers

    SciTech Connect

    Pourhamidi, A.H.

    1983-10-01

    It was previously thought that diagnostic or therapeutic ionizing radiation did not have an adverse effect on the function of cardiac pacemakers. Recently, however, some authors have reported damaging effect of therapeutic radiation on cardiac pulse generators. An analysis of a recently-extracted pacemaker documented the effect of radiation on the pacemaker pulse generator.

  7. Acute Cerebrovascular Radiation Syndrome: Radiation Neurotoxicity , mechanisms of CNS radiation injury, advanced countermeasures for Radiation Protection of Central Nervous System.

    NASA Astrophysics Data System (ADS)

    Popov, Dmitri; Jones, Jeffrey; Maliev, Slava

    Key words: Cerebrovascular Acute Radiation Syndrome (Cv ARS), Radiation Neurotoxins (RNT), Neurotransmitters, Radiation Countermeasures, Antiradiation Vaccine (ArV), Antiradiation Blocking Antibodies, Antiradiation Antidote. Psychoneuroimmunology, Neurotoxicity. ABSTRACT: To review the role of Radiation Neurotoxins in triggering, developing of radiation induced central nervous system injury. Radiation Neurotoxins - rapidly acting blood toxic lethal agent, which activated after irradiation and concentrated, circulated in interstitial fluid, lymph, blood with interactions with cell membranes, receptors and cell compartments. Radiation Neurotoxins - biological molecules with high enzymatic activity and/or specific lipids and activated or modified after irradiation. The Radiation Neurotoxins induce increased permeability of blood vessels, disruption of the blood-brain barrier, blood-cerebrospinal fluid (CSF) barrier and developing severe disorder of blood macro- and micro-circulation. Principles of Radiation Psychoneuro-immunology and Psychoneuro-allergology were applied for determination of pathological processes developed after irradiation or selective administration of Radiation Neurotoxins to radiation naïve mammals. Effects of radiation and exposure to radiation can develop severe irreversible abnormalities of Central Nervous System, brain structures and functions. Antiradiation Vaccine - most effective, advanced methods of protection, prevention, mitigation and treatment and was used for of Acute Radiation Syndromes and elaboration of new technology for immune-prophylaxis and immune-protection against ϒ, Heavy Ion, Neutron irradiation. Results of experiments suggested that blocking, antitoxic, antiradiation antibodies can significantly reduce toxicity of Radiation Toxins. New advanced technology include active immune-prophylaxis with Antiradiation Vaccine and Antiradiation therapy that included specific blocking antibodies to Radiation Neurotoxins

  8. [Solar cosmic radiation and the radiation hazard of space flight].

    PubMed

    Miroshnichenko, L I

    1983-01-01

    Present-day data on the spectrum of solar radiation in the source and near the Earth are discussed as applied to the radiation safety of crewmembers and electronics onboard manned and unmanned spacecraft. It is shown that the slope of the solar radiation spectrum changes (flattens) in the low energy range. Quantitative information about absolute solar radiation fluxes near the Earth is summarized in relation to the most significant flares of 1956--1978. The time-related evolution of the solar radiation spectrum in the interplanetary space is described in quantitative terms (as illustrated by the solar flare of 28 September 1961). It is indicated that the nonmonotonic energy dependence of the transport path of solar radiation in the interplanetary space should be taken into consideration. It is demonstrated that the diffusion model of propagation can be verified using solar radiation measurements in space flights.

  9. Radiation dosimetry and biophysical models of space radiation effects

    NASA Technical Reports Server (NTRS)

    Cucinotta, Francis A.; Wu, Honglu; Shavers, Mark R.; George, Kerry

    2003-01-01

    Estimating the biological risks from space radiation remains a difficult problem because of the many radiation types including protons, heavy ions, and secondary neutrons, and the absence of epidemiology data for these radiation types. Developing useful biophysical parameters or models that relate energy deposition by space particles to the probabilities of biological outcomes is a complex problem. Physical measurements of space radiation include the absorbed dose, dose equivalent, and linear energy transfer (LET) spectra. In contrast to conventional dosimetric methods, models of radiation track structure provide descriptions of energy deposition events in biomolecules, cells, or tissues, which can be used to develop biophysical models of radiation risks. In this paper, we address the biophysical description of heavy particle tracks in the context of the interpretation of both space radiation dosimetry and radiobiology data, which may provide insights into new approaches to these problems.

  10. On source radiation

    NASA Technical Reports Server (NTRS)

    Levine, H.

    1980-01-01

    The power output from given sources is usually ascertained via an energy flux integral over the normal directions to a remote (far field) surface; an alternative procedure, which utilizes an integral that specifies the direct rate of working by the source on the resultant field, is described and illustrated for both point and continuous source distribution. A comparison between the respective procedures is made in the analysis of sound radiated from a periodic dipole source whose axis performs a periodic plane angular movement about a fixed direction. Thus, adopting a conventional approach, Sretenskii (1956) characterizes the rotating dipole in terms of an infinite number of stationary ones along a pari of orthogonal directions in the plane, and through the far field representation of the latter, arrives at a series development for the instantaneous radiated power, whereas the local manner of power calculation dispenses with the equivalent infinite aggregate of sources and yields a compact analytical result.

  11. Radiation Induced Genomic Instability

    SciTech Connect

    Morgan, William F.

    2011-03-01

    Radiation induced genomic instability can be observed in the progeny of irradiated cells multiple generations after irradiation of parental cells. The phenotype is well established both in vivo (Morgan 2003) and in vitro (Morgan 2003), and may be critical in radiation carcinogenesis (Little 2000, Huang et al. 2003). Instability can be induced by both the deposition of energy in irradiated cells as well as by signals transmitted by irradiated (targeted) cells to non-irradiated (non-targeted) cells (Kadhim et al. 1992, Lorimore et al. 1998). Thus both targeted and non-targeted cells can pass on the legacy of radiation to their progeny. However the radiation induced events and cellular processes that respond to both targeted and non-targeted radiation effects that lead to the unstable phenotype remain elusive. The cell system we have used to study radiation induced genomic instability utilizes human hamster GM10115 cells. These cells have a single copy of human chromosome 4 in a background of hamster chromosomes. Instability is evaluated in the clonal progeny of irradiated cells and a clone is considered unstable if it contains three or more metaphase sub-populations involving unique rearrangements of the human chromosome (Marder and Morgan 1993). Many of these unstable clones have been maintained in culture for many years and have been extensively characterized. As initially described by Clutton et al., (Clutton et al. 1996) many of our unstable clones exhibit persistently elevated levels of reactive oxygen species (Limoli et al. 2003), which appear to be due dysfunctional mitochondria (Kim et al. 2006, Kim et al. 2006). Interestingly, but perhaps not surprisingly, our unstable clones do not demonstrate a “mutator phenotype” (Limoli et al. 1997), but they do continue to rearrange their genomes for many years. The limiting factor with this system is the target – the human chromosome. While some clones demonstrate amplification of this chromosome and thus lend

  12. Semiconductor radiation detector

    DOEpatents

    Patt, Bradley E.; Iwanczyk, Jan S.; Tull, Carolyn R.; Vilkelis, Gintas

    2002-01-01

    A semiconductor radiation detector is provided to detect x-ray and light photons. The entrance electrode is segmented by using variable doping concentrations. Further, the entrance electrode is physically segmented by inserting n+ regions between p+ regions. The p+ regions and the n+ regions are individually biased. The detector elements can be used in an array, and the p+ regions and the n+ regions can be biased by applying potential at a single point. The back side of the semiconductor radiation detector has an n+ anode for collecting created charges and a number of p+ cathodes. Biased n+ inserts can be placed between the p+ cathodes, and an internal resistor divider can be used to bias the n+ inserts as well as the p+ cathodes. A polysilicon spiral guard can be implemented surrounding the active area of the entrance electrode or surrounding an array of entrance electrodes.

  13. Pathology of radiation myelopathy

    PubMed Central

    Burns, R. J.; Jones, A. N.; Robertson, J. S.

    1972-01-01

    After nothing the rarity of papers describing the pathology of delayed radiation necrosis of the spinal cord, the clinical and pathological findings from four cases are presented. The main pathological features are asymmetric demyelination of the lateral columns and to a lesser degree the posterior and anterior columns of white matter, with coagulative necrosis at the level of irradiation which affected the grey matter to a lesser degree. There is ascending and descending secondary tract degeneration, and poor glial response in the lesions themselves. Vascular changes, mainly hyalilne thickening of arteriolar walls, are present, but not in degree sufficient to explain the primary lesion. The discussion of the pathogenesis of the myelopathy weighs the merits of a primary vascular lesion against those of a primary effect of the radiation on neural tissue. The latter is favoured. Images PMID:4647860

  14. Terahertz radiation mixer

    DOEpatents

    Wanke, Michael C.; Allen, S. James; Lee, Mark

    2008-05-20

    A terahertz radiation mixer comprises a heterodyned field-effect transistor (FET) having a high electron mobility heterostructure that provides a gatable two-dimensional electron gas in the channel region of the FET. The mixer can operate in either a broadband pinch-off mode or a narrowband resonant plasmon mode by changing a grating gate bias of the FET. The mixer can beat an RF signal frequency against a local oscillator frequency to generate an intermediate frequency difference signal in the microwave region. The mixer can have a low local oscillator power requirement and a large intermediate frequency bandwidth. The terahertz radiation mixer is particularly useful for terahertz applications requiring high resolution.

  15. Time encoded radiation imaging

    DOEpatents

    Marleau, Peter; Brubaker, Erik; Kiff, Scott

    2014-10-21

    The various technologies presented herein relate to detecting nuclear material at a large stand-off distance. An imaging system is presented which can detect nuclear material by utilizing time encoded imaging relating to maximum and minimum radiation particle counts rates. The imaging system is integrated with a data acquisition system that can utilize variations in photon pulse shape to discriminate between neutron and gamma-ray interactions. Modulation in the detected neutron count rates as a function of the angular orientation of the detector due to attenuation of neighboring detectors is utilized to reconstruct the neutron source distribution over 360 degrees around the imaging system. Neutrons (e.g., fast neutrons) and/or gamma-rays are incident upon scintillation material in the imager, the photons generated by the scintillation material are converted to electrical energy from which the respective neutrons/gamma rays can be determined and, accordingly, a direction to, and the location of, a radiation source identified.

  16. Accepting space radiation risks.

    PubMed

    Schimmerling, Walter

    2010-08-01

    The human exploration of space inevitably involves exposure to radiation. Associated with this exposure are multiple risks, i.e., probabilities that certain aspects of an astronaut's health or performance will be degraded. The management of these risks requires that such probabilities be accurately predicted, that the actual exposures be verified, and that comprehensive records be maintained. Implicit in these actions is the fact that, at some point, a decision has been made to accept a certain level of risk. This paper examines ethical and practical considerations involved in arriving at a determination that risks are acceptable, roles that the parties involved may play, and obligations arising out of reliance on the informed consent paradigm seen as the basis for ethical radiation risk acceptance in space.

  17. Ultraviolet radiation effects

    NASA Technical Reports Server (NTRS)

    Slemp, Wayne S.

    1989-01-01

    Solar ultraviolet testing was not developed which will provide highly accelerated (20 to 50X) exposures that correlate to flight test data. Additional studies are required to develop an exposure methodology which will assure that accelerated testing can be used for qualification of materials and coatings for long duration space flight. Some conclusions are listed: Solar UV radiation is present in all orbital environments; Solar UV does not change in flux with orbital altitude; UV radiation can degrade most coatings and polymeric films; Laboratory UV simulation methodology is needed for accelerated testing to 20 UV solar constants; Simulation of extreme UV (below 200 nm) is needed to evaluate requirements for EUV in solar simulation.

  18. TOPEX orbital radiation study

    NASA Technical Reports Server (NTRS)

    Stassinopoulos, E. G.; Barth, J. M.

    1984-01-01

    The space radiation environment of the TOPEX spacecraft is investigated. A single trajectory was considered. The external (surface incident) charged particle radiation, predicted for the satellite, is determined by orbital flux integration for the specified trajectory. The latest standard models of the environment are used in the calculations. The evaluation is performed for solar maximum conditions. The spacecraft exposure to cosmic rays of galactic origin is evaluated over its flight path through the magnetosphere in terms of geomagnetic shielding effects, both for surface incident heavy ions and for particles emerging behind different material thickness. Limited shielding and dose evaluations are performed for simple infinite slab and spherical geometries. Results, given in graphical and tabular form, are analyzed, explained, and discussed. Conclusions are presented and commented on.

  19. Radiation Effects in Zircon

    SciTech Connect

    Ewing, Rodney C.; Meldrum, Alkiviathes; Wang, L. M.; Weber, William J.; Corrales, Louis R.

    2003-12-11

    The widespread distribution of zircon in the continental crust, its tendency to concentrate trace elements, particularly lanthanides and actinides, its use in age-dating, and its resistance to chemical and physical degradation have made zircon the most important accessory mineral in geologic studies. Because zircon is highly refractory, it also has important industrial applications, including its use as a lining material in high-temperature furnaces. However, during the past decade, zircon has also been proposed for advanced technology applications, such as a durable material for the immobilization of plutonium or, when modified by ion-beam irradiation, as an optic waveguide material. In all of these applications, the change in properties as a function of increasing radiation dose is of critical importance. In this chapter, we summarize the state-of-knowledge on the radiation damage accumulation process in zircon.

  20. Handheld CZT radiation detector

    DOEpatents

    Murray, William S.; Butterfield, Kenneth B.; Baird, William

    2004-08-24

    A handheld CZT radiation detector having a CZT gamma-ray sensor, a multichannel analyzer, a fuzzy-logic component, and a display component is disclosed. The CZT gamma-ray sensor may be a coplanar grid CZT gamma-ray sensor, which provides high-quality gamma-ray analysis at a wide range of operating temperatures. The multichannel analyzer categorizes pulses produce by the CZT gamma-ray sensor into channels (discrete energy levels), resulting in pulse height data. The fuzzy-logic component analyzes the pulse height data and produces a ranked listing of radioisotopes. The fuzzy-logic component is flexible and well-suited to in-field analysis of radioisotopes. The display component may be a personal data assistant, which provides a user-friendly method of interacting with the detector. In addition, the radiation detector may be equipped with a neutron sensor to provide an enhanced mechanism of sensing radioactive materials.

  1. Radiation shielding composition

    DOEpatents

    Quapp, W.J.; Lessing, P.A.

    1998-07-28

    A composition is disclosed for use as a radiation shield. The shield is a concrete product containing a stable uranium aggregate for attenuating gamma rays and a neutron absorbing component, the uranium aggregate and neutron absorbing component being present in the concrete product in sufficient amounts to provide a concrete having a density between about 4 and about 15 grams/cm{sup 3} and which will at a predetermined thickness, attenuate gamma rays and absorb neutrons from a radioactive material of projected gamma ray and neutron emissions over a determined time period. The composition is preferably in the form of a container for storing radioactive materials that emit gamma rays and neutrons. The concrete container preferably comprises a metal liner and/or a metal outer shell. The resulting radiation shielding container has the potential of being structurally sound, stable over a long period of time, and, if desired, readily mobile. 5 figs.

  2. Radiation shielding composition

    DOEpatents

    Quapp, William J.; Lessing, Paul A.

    2000-12-26

    A composition for use as a radiation shield. The shield is a concrete product containing a stable uranium aggregate for attenuating gamma rays and a neutron absorbing component, the uranium aggregate and neutron absorbing component being present in the concrete product in sufficient amounts to provide a concrete having a density between about 4 and about 15 grams/cm.sup.3 and which will at a predetermined thickness, attenuate gamma rays and absorb neutrons from a radioactive material of projected gamma ray and neutron emissions over a determined time period. The composition is preferably in the form of a container for storing radioactive materials that emit gamma rays and neutrons. The concrete container preferably comprises a metal liner and/or a metal outer shell. The resulting radiation shielding container has the potential of being structurally sound, stable over a long period of time, and, if desired, readily mobile.

  3. Radiation shielding composition

    DOEpatents

    Quapp, William J.; Lessing, Paul A.

    1998-01-01

    A composition for use as a radiation shield. The shield is a concrete product containing a stable uranium aggregate for attenuating gamma rays and a neutron absorbing component, the uranium aggregate and neutron absorbing component being present in the concrete product in sufficient amounts to provide a concrete having a density between about 4 and about 15 grams/cm.sup.3 and which will at a predetermined thickness, attenuate gamma rays and absorb neutrons from a radioactive material of projected gamma ray and neutron emissions over a determined time period. The composition is preferably in the form of a container for storing radioactive materials that emit gamma rays and neutrons. The concrete container preferably comprises a metal liner and/or a metal outer shell. The resulting radiation shielding container has the potential of being structurally sound, stable over a long period of time, and, if desired, readily mobile.

  4. Radiative B Decays

    SciTech Connect

    Bard, D.; /Imperial Coll., London

    2011-11-23

    I discuss recent results in radiative B decays from the Belle and BaBar collaborations. I report new measurements of the decay rate and CP asymmetries in b {yields} s{gamma} and b {yields} d{gamma} decays, and measurements of the photon spectrum in b {yields} s{gamma}. Radiative penguin decays are flavour changing neutral currents which do not occur at tree level in the standard model (SM), but must proceed via one loop or higher order diagrams. These transitions are therefore suppressed in the SM, but offer access to poorlyknown SM parameters and are also a sensitive probe of new physics. In the SM, the rate is dominated by the top quark contribution to the loop, but non-SM particles could also contribute with a size comparable to leading SM contributions. The new physics effects are potentially large which makes them theoretically very interesting, but due to their small branching fractions they are typically experimentally challenging.

  5. Radiation characterization summary :

    SciTech Connect

    Parma, Edward J.,; Quirk, Thomas J.; Lippert, Lance L.; Griffin, Patrick J; Naranjo, Gerald E.; Luker, Spencer Michael

    2013-04-01

    This document presents the facility-recommended characterization of the neutron, prompt gamma-ray, and delayed gamma-ray radiation fields in the Annular Core Research Reactor (ACRR) for the 44-inch-long lead-boron bucket in the central cavity on the 32-inch pedestal at the core centerline. The designation for this environment is ACRR-LB44-CC-32-cl. The neutron, prompt gamma-ray, and delayed gamma-ray energy spectra are presented as well as radial and axial neutron and gamma-ray flux profiles within the experiment area of the bucket. Recommended constants are given to facilitate the conversion of various dosimetry readings into radiation metrics desired by experimenters. Representative pulse and steady-state operations are presented with conversion examples.

  6. Radiation Environment Inside Spacecraft

    NASA Technical Reports Server (NTRS)

    O'Neill, Patrick

    2015-01-01

    Dr. Patrick O'Neill, NASA Johnson Space Center, will present a detailed description of the radiation environment inside spacecraft. The free space (outside) solar and galactic cosmic ray and trapped Van Allen belt proton spectra are significantly modified as these ions propagate through various thicknesses of spacecraft structure and shielding material. In addition to energy loss, secondary ions are created as the ions interact with the structure materials. Nuclear interaction codes (FLUKA, GEANT4, HZTRAN, MCNPX, CEM03, and PHITS) transport free space spectra through different thicknesses of various materials. These "inside" energy spectra are then converted to Linear Energy Transfer (LET) spectra and dose rate - that's what's needed by electronics systems designers. Model predictions are compared to radiation measurements made by instruments such as the Intra-Vehicular Charged Particle Directional Spectrometer (IV-CPDS) used inside the Space Station, Orion, and Space Shuttle.

  7. Genetic susceptibility to radiation

    NASA Astrophysics Data System (ADS)

    Hall, E. J.; Brenner, D. J.; Worgul, B.; Smilenov, L.

    In the context of space radiation, it is important to know whether the human population includes genetically predisposed radiosensitive subsets. One possibility is that haploinsufficiency for ATM confers radiosensitivity, and this defect involves 1-3% of the population. Using knock-out mice we chose to study cataractogenesis in the lens and oncogenic transformation in mouse embryo fibroblasts to assay for effects of ATM deficiency. Radiation induced cataracts appeared earlier in the heterozygous versus wild-type animals following exposure to either gamma rays or 1 GeV/nucleon iron ions. In addition, it was found that embryo fibroblasts of Atm heterozygotes showed an increased incidence of oncogenic transformation compared with their normal litter-matched counterparts. From these data we suggest that Ataxia Telangiectasia heterozygotes could indeed represent a societally-significant radiosensitive subpopulation.

  8. Genesis Radiation Environment

    NASA Technical Reports Server (NTRS)

    Minow, Joseph I.; Altstatt, Richard L.; Skipworth, William C.

    2007-01-01

    The Genesis spacecraft launched on 8 August 2001 sampled solar wind environments at L1 from 2001 to 2004. After the Science Capsule door was opened, numerous foils and samples were exposed to the various solar wind environments during periods including slow solar wind from the streamer belts, fast solar wind flows from coronal holes, and coronal mass ejections. The Survey and Examination of Eroded Returned Surfaces (SEERS) program led by NASA's Space Environments and Effects program had initiated access for the space materials community to the remaining Science Capsule hardware after the science samples had been removed for evaluation of materials exposure to the space environment. This presentation will describe the process used to generate a reference radiation Genesis Radiation Environment developed for the SEERS program for use by the materials science community in their analyses of the Genesis hardware.

  9. Aharonov-Bohm radiation

    SciTech Connect

    Jones-Smith, Katherine; Mathur, Harsh; Vachaspati, Tanmay

    2010-02-15

    A solenoid oscillating in vacuum will pair produce charged particles due to the Aharonov-Bohm (AB) interaction. We calculate the radiation pattern and power emitted for charged scalar particles. We extend the solenoid analysis to cosmic strings and find enhanced radiation from cusps and kinks on loops. We argue by analogy with the electromagnetic AB interaction that cosmic strings should emit photons due to the gravitational AB interaction of fields in the conical spacetime of a cosmic string. We calculate the emission from a kink and find that it is of similar order as emission from a cusp, but kinks are vastly more numerous than cusps and may provide a more interesting observational signature.

  10. Radiation optic neuropathy

    SciTech Connect

    Kline, L.B.; Kim, J.Y.; Ceballos, R.

    1985-08-01

    Following surgery for pituitary adenoma, radiation therapy is an accepted treatment in reducing tumor recurrence. However, a potential therapeutic complication is delayed radionecrosis of perisellar neural structures, including the optic nerves and chiasm. This particular cause of visual loss, radiation optic neuropathy (RON), has not been emphasized in the ophthalmologic literature. Four cases of RON seen in the past five years are reported. Diagnostic criteria include: (1) acute visual loss (monocular or binocular), (2) visual field defects indicating optic nerve or chiasmal dysfunction, (3) absence of optic disc edema, (4) onset usually within three years of therapy (peak: 1-1 1/2 years), and (5) no computed tomographic evidence of visual pathway compression. Pathologic findings, differential diagnosis and therapy will be discussed in outlining the clinical profile of RON.

  11. National Ambient Radiation Database

    SciTech Connect

    Dziuban, J.; Sears, R.

    2003-02-25

    The U.S. Environmental Protection Agency (EPA) recently developed a searchable database and website for the Environmental Radiation Ambient Monitoring System (ERAMS) data. This site contains nationwide radiation monitoring data for air particulates, precipitation, drinking water, surface water and pasteurized milk. This site provides location-specific as well as national information on environmental radioactivity across several media. It provides high quality data for assessing public exposure and environmental impacts resulting from nuclear emergencies and provides baseline data during routine conditions. The database and website are accessible at www.epa.gov/enviro/. This site contains (1) a query for the general public which is easy to use--limits the amount of information provided, but includes the ability to graph the data with risk benchmarks and (2) a query for a more technical user which allows access to all of the data in the database, (3) background information on ER AMS.

  12. Radiation degradation of cellulose

    NASA Astrophysics Data System (ADS)

    Leonhardt, J.; Arnold, G.; Baer, M.; Langguth, H.; Gey, M.; Hübert, S.

    The application of straw and other cellulose polymers as feedstuff for ruminants is limited by its low digestibility. During recent decades it was attempted to increase the digestibility of straw by several chemical and physical methods. In this work some results of the degradation of gamma and electron treated wheat straw are reported. Complex methods of treatment (e.g. radiation influence and influence of lyes) are taken into consideration. In vitro-experiments with radiation treated straw show that the digestibility can be increased from 20 % up to about 80 %. A high pressure liquid chromatography method was used to analyze the hydrolysates. The contents of certain species of carbohydrates in the hydrolysates in dependence on the applied dose are given.

  13. Biochemistry of ionizing radiation

    SciTech Connect

    Walden, T.L.; Nushin, F.K.

    1990-01-01

    This volume examines the biochemical changes occurring in normal tissue after irradiation. A review of radiation chemistry is followed by an analysis of factors affecting biochemical responses and a timely discussion of radiobiology in space flight. The authors then describe the effects of radiation on lipid peroxidation, amino acids, peptides, proteins, polysaccharides, DNA, thiols, and body fluids. Close attention is given to alterations in biological mediators such as eicosanoids, cyclic nucleotides, angiotensin, histamine, polyamines, catecholamines, and serotonin and in hormones such as adrenocorticotropic hormone, testosterone, estrogens, follicle-stimulating hormone, luteinizing hormone, thyroid hormones, insulin and glucagon, gastrin, and melatonin. Other chapters focus on changes in carbohydrate metabolism, oxidative phosphorylation, protein synthesis, and serum proteins. A chapter on biological dosimeters discusses prodromal syndrome, hematological dosimeters, serum composition, urine, chromosomal aberrations, and fluorometric and immunoassays.

  14. Radiation-induced schwannomas

    SciTech Connect

    Rubinstein, A.B.; Reichenthal, E.; Borohov, H.

    1989-06-01

    The histopathology and clinical course of three patients with schwannomas of the brain and high cervical cord after therapeutic irradiation for intracranial malignancy and for ringworm of the scalp are described. Earlier reports in the literature indicated that radiation of the scalp may induce tumors in the head and neck. It is therefore suggested that therapeutic irradiation in these instances was a causative factor in the genesis of these tumors.

  15. Radiation and circulatory disease.

    PubMed

    Little, Mark P

    Exposure to therapeutic doses of ionizing radiation is associated with damage to the heart and coronary arteries. However, only recently have studies with high-quality individual dosimetry data allowed this risk to be quantified while also adjusting for concomitant chemotherapy, and medical and lifestyle risk factors. At lower levels of exposure the evidence is less clear. In this article I review radiation-associated risks of circulatory disease in groups treated with radiotherapy for malignant and non-malignant disease, and in occupationally- or environmentally-exposed groups receiving rather lower levels of radiation dose, also for medical diagnostic purposes. Results of a meta-analysis suggest that excess relative risks per unit dose for various types of heart disease do not exhibit statistically significant (p>0.2) heterogeneity between studies. Although there are no marked discrepancies between risks derived from the high-dose therapeutic and medical diagnostic studies and from the moderate/low dose occupational and environmental studies, at least for ischemic heart disease and stroke there are indications of larger risks per unit dose for lower dose rate and fractionated exposures. Risks for stroke and other types of circulatory disease are significantly more variable (p<0.0001), possibly resulting from confounding and effect-modification by well known (but unobserved) risk factors. Adjustment for any of mean dose, dose fractionation or age at exposure results in the residual heterogeneity for cerebrovascular disease becoming non-significant. The review provides strong evidence in support of a causal association between both low and high dose radiation exposure and most types of circulatory disease.

  16. Radiation in Yolo County

    NASA Astrophysics Data System (ADS)

    Dickie, H.; Colwell, K.

    2013-12-01

    In today's post-nuclear age, there are many man-made sources of radioactivity, in addition to the natural background we expect from cosmic and terrestrial origins. While all atoms possess unstable isotopes, there are few that are abundant enough, energetic enough, and have long enough half-lives to pose a signicant risk of ionizing radiation exposure. We hypothesize a decreasing relative radiation measurement (in detected counts per minute [CPM]) at nine locations that might pose occupational or environmental hazard: 1. A supermarket produce aisle (living tissue has high concentration of 40K) 2. A hospital (medical imaging uses X-rays and radioactive dyes) 3. The electronics section of a superstore (high voltage electronics have the potential to produce ionizing radiation) 4. An electrical transformer (similar reasons) 5. An antique store (some ceramics and glazes use radioisotopes that are now outlawed) 6. A gasoline pump (processing and terrestrial isotope contamination might leave a radioactive residue) 7. A fertilized eld (phosphate rock contains uranium and thorium, in addition to potassium) 8. A house (hopefully mild background, but potential radon contamination) 9. A school (should be radiologically neutral) We tested the hypothesis by measuring 100 minutes of counts on a self-assembled MightyOhmTM Geiger counter at each location. Our results show that contrary to the hypothesized ordering, the house was the most radiologically active. We present possible explanations for the observed radiation levels, as well as possible sources of measurement error, possible consequences of prolonged exposure to the measured levels, and suggestions for decreasing exposure and environmental impact.

  17. Commercial Parts Radiation Testing

    DTIC Science & Technology

    2015-01-13

    AFRL /RVIL Kirtland AFB, NM 87117-5776 2 cys Official Record Copy AFRL /RVSE/Keith Avery 1 cy ... AFRL -RV-PS- AFRL -RV-PS- TR-2014-0172 TR-2014-0172 COMMERCIAL PARTS RADIATION TESTING Craig J. Kief COSMIAC at UNM 2350 Alamo Avenue SE Suite 300...Vehicles Directorate 3550 Aberdeen Ave SE AIR FORCE MATERIEL COMMAND KIRTLAND AIR FORCE BASE, NM 87117-5776 DTIC COPY NOTICE AND SIGNATURE

  18. VUV Radiation and Breakdown

    DTIC Science & Technology

    2011-02-28

    ultraviolet light on surface breakdown. The first experimental setup was designed so that VUV emission from an excited surface flashover event is focused onto...name attached. Garrett Rogers An experimental setup used to study pulsed dielectric surface flashover in various gases at atmospheric pressure...radiation on streamer propagation. A significant amount of VUV emission was observed from excited surface flashover events, and most of this

  19. Microwave Radiation and Thermoregulation.

    DTIC Science & Technology

    1985-05-01

    environment ................................................ 33 19. A plot of dry heat losses as a function of the skin-to- ambient temperature gradient...avapora- - on of water to be 0.72 W-h/g. Dry heat exchanged with the environment ’hrough convection C and radiation R must be expressed in terms of...microwave field was present, the animals were observed to sit much more quietly than during the equilibration period, often with eyes closed as though

  20. Radiation biology of mosquitoes

    PubMed Central

    Helinski, Michelle EH; Parker, Andrew G; Knols, Bart GJ

    2009-01-01

    There is currently renewed interest in assessing the feasibility of the sterile insect technique (SIT) to control African malaria vectors in designated areas. The SIT relies on the sterilization of males before mass release, with sterilization currently being achieved through the use of ionizing radiation. This paper reviews previous work on radiation sterilization of Anopheles mosquitoes. In general, the pupal stage was irradiated due to ease of handling compared to the adult stage. The dose-response curve between the induced sterility and log (dose) was shown to be sigmoid, and there was a marked species difference in radiation sensitivity. Mating competitiveness studies have generally been performed under laboratory conditions. The competitiveness of males irradiated at high doses was relatively poor, but with increasing ratios of sterile males, egg hatch could be lowered effectively. Males irradiated as pupae had a lower competitiveness compared to males irradiated as adults, but the use of partially-sterilizing doses has not been studied extensively. Methods to reduce somatic damage during the irradiation process as well as the use of other agents or techniques to induce sterility are discussed. It is concluded that the optimal radiation dose chosen for insects that are to be released during an SIT programme should ensure a balance between induced sterility of males and their field competitiveness, with competitiveness being determined under (semi-) field conditions. Self-contained 60Co research irradiators remain the most practical irradiators but these are likely to be replaced in the future by a new generation of high output X ray irradiators. PMID:19917076

  1. RADIATION SHIELDING DEVICE

    DOEpatents

    Wigner, E.P.; Young, G.J.

    1958-09-23

    ABS>A radiation shield that is suitable for the protection of personnel from both gamma rays and nentrons is described. The shield is comprised of a hollow wall and an aggregate consisting of iron and water in approximately equal amounts by volume substantially filling the wall. A means is provided to circulate the water through the wall to cool the shield when in use.

  2. Nonadaptive radiation in damselflies.

    PubMed

    Wellenreuther, Maren; Sánchez-Guillén, Rosa Ana

    2016-01-01

    Adaptive radiations have long served as living libraries to study the build-up of species richness; however, they do not provide good models for radiations that exhibit negligible adaptive disparity. Here, we review work on damselflies to argue that nonadaptive mechanisms were predominant in the radiation of this group and have driven species divergence through sexual selection arising from male-female mating interactions. Three damselfly genera (Calopteryx,Enallagma and Ischnura) are highlighted and the extent of (i) adaptive ecological divergence in niche use and (ii) nonadaptive differentiation in characters associated with reproduction (e.g. sexual morphology and behaviours) was evaluated. We demonstrate that species diversification in the genus Calopteryx is caused by nonadaptive divergence in coloration and behaviour affecting premating isolation, and structural differentiation in reproductive morphology affecting postmating isolation. Similarly, the vast majority of diversification events in the sister genera Enallagma and Ischnura are entirely driven by differentiation in genital structures used in species recognition. The finding that closely related species can show negligible ecological differences yet are completely reproductively isolated suggests that the evolution of reproductive isolation can be uncoupled from niche-based divergent natural selection, challenging traditional niche models of species coexistence.

  3. Microbeam radiation therapy

    NASA Astrophysics Data System (ADS)

    Laissue, Jean A.; Lyubimova, Nadia; Wagner, Hans-Peter; Archer, David W.; Slatkin, Daniel N.; Di Michiel, Marco; Nemoz, Christian; Renier, Michel; Brauer, Elke; Spanne, Per O.; Gebbers, Jan-Olef; Dixon, Keith; Blattmann, Hans

    1999-10-01

    The central nervous system of vertebrates, even when immature, displays extraordinary resistance to damage by microscopically narrow, multiple, parallel, planar beams of x rays. Imminently lethal gliosarcomas in the brains of mature rats can be inhibited and ablated by such microbeams with little or no harm to mature brain tissues and neurological function. Potentially palliative, conventional wide-beam radiotherapy of malignant brain tumors in human infants under three years of age is so fraught with the danger of disrupting the functional maturation of immature brain tissues around the targeted tumor that it is implemented infrequently. Other kinds of therapy for such tumors are often inadequate. We suggest that microbeam radiation therapy (MRT) might help to alleviate the situation. Wiggler-generated synchrotron x-rays were first used for experimental microplanar beam (microbeam) radiation therapy (MRT) at Brookhaven National Laboratory's National Synchrotron Light Source in the early 1990s. We now describe the progress achieved in MRT research to date using immature and adult rats irradiated at the European Synchrotron Radiation Facility in Grenoble, France, and investigated thereafter at the Institute of Pathology of the University of Bern.

  4. Radiation takes its Toll

    PubMed Central

    Ratikan, Josephine A.; Micewicz, Ewa D.; Xie, Michael W.; Schaue, Dörthe

    2015-01-01

    The ability to recognize and respond to universal molecular patterns on invading microorganisms allows our immune system to stay on high alert, sensing danger to our self-integrity. Our own damaged cells and tissues in pathological situations activate similar warning systems as microbes. In this way, the body is able to mount a response that is appropriate to the danger. Toll-like receptors are at the heart of this pattern recognition system that initiates innate pro-oxidant, pro-inflammatory signaling cascades and ultimately bridges recognition of danger to adaptive immunity. The acute inflammatory lesions that are formed segue into resolution of inflammation, repair and healing or, more dysfunctionally, into chronic inflammation, autoimmunity, excessive tissue damage and carcinogenesis. Redox is at the nexus of this decision making process and is the point at which ionizing radiation initially intercepts to trigger similar responses to self-damage. In this review we discuss our current understanding of how radiation-damaged cells interact with Toll-like receptors and how the immune systems interprets these radiation-induced danger signals in the context of whole-body exposures and during local tumor irradiation. PMID:25819030

  5. Intraocular radiation blocking

    SciTech Connect

    Finger, P.T.; Ho, T.K.; Fastenberg, D.M.; Hyman, R.A.; Stroh, E.M.; Packer, S.; Perry, H.D. )

    1990-09-01

    Iodine-based liquid radiographic contrast agents were placed in normal and tumor-bearing (Greene strain) rabbit eyes to evaluate their ability to block iodine-125 radiation. This experiment required the procedures of tumor implantation, vitrectomy, air-fluid exchange, and 125I plaque and thermoluminescent dosimetry (TLD) chip implantation. The authors quantified the amount of radiation attenuation provided by intraocularly placed contrast agents with in vivo dosimetry. After intraocular insertion of a blocking agent or sham blocker (saline) insertion, episcleral 125I plaques were placed across the eye from episcleral TLD dosimeters. This showed that radiation attenuation occurred after blocker insertion compared with the saline controls. Then computed tomographic imaging techniques were used to describe the relatively rapid transit time of the aqueous-based iohexol compared with the slow transit time of the oil-like iophendylate. Lastly, seven nontumor-bearing eyes were primarily examined for blocking agent-related ocular toxicity. Although it was noted that iophendylate induced intraocular inflammation and retinal degeneration, all iohexol-treated eyes were similar to the control eyes at 7 and 31 days of follow-up. Although our study suggests that intraocular radiopaque materials can be used to shield normal ocular structures during 125I plaque irradiation, a mechanism to keep these materials from exiting the eye must be devised before clinical application.

  6. Understanding Radiation Thermometry. Part I

    NASA Technical Reports Server (NTRS)

    Risch Timothy K.

    2015-01-01

    This document is a two-part course on the theory and practice of radiation thermometry. Radiation thermometry is the technique for determining the temperature of a surface or a volume by measuring the electromagnetic radiation it emits. This course covers the theory and practice of radiative thermometry and emphasizes the modern application of the field using commercially available electronic detectors and optical components. The course covers the historical development of the field, the fundamental physics of radiative surfaces, along with modern measurement methods and equipment.

  7. Hawking radiation from black rings

    SciTech Connect

    Miyamoto, Umpei; Murata, Keiju

    2008-01-15

    We calculate the quantum radiation from the 5-dimensional charged rotating black rings by demanding the radiation eliminate the possible anomalies on the horizons. It is shown that the temperature, energy flux, and angular-momentum flux exactly coincide with those of the Hawking radiation. The black rings considered in this paper contain the Myers-Perry black hole as a limit, and the quantum radiation for this black hole, obtained in the literature, is recovered in the limit. The results support the picture that the Hawking radiation can be regarded as the anomaly eliminator on horizons and suggest its general applicability to the higher-dimensional black holes discovered recently.

  8. Josephson-vortex Cherenkov radiation

    SciTech Connect

    Mints, R.G.; Snapiro, I.B.

    1995-10-01

    We predict the Josephson-vortex Cherenkov radiation of an electromagnetic wave. We treat a long one-dimensional Josephson junction. We consider the wavelength of the radiated electromagnetic wave to be much less than the Josephson penetration depth. We use for calculations the nonlocal Josephson electrodynamics. We find the expression for the radiated power and for the radiation friction force acting on a Josephson vortex and arising due to the Cherenkov radiation. We calculate the relation between the density of the bias current and the Josephson vortex velocity.

  9. Understanding Radiation Thermometry. Part II

    NASA Technical Reports Server (NTRS)

    Risch, Timothy K.

    2015-01-01

    This document is a two-part course on the theory and practice of radiation thermometry. Radiation thermometry is the technique for determining the temperature of a surface or a volume by measuring the electromagnetic radiation it emits. This course covers the theory and practice of radiative thermometry and emphasizes the modern application of the field using commercially available electronic detectors and optical components. The course covers the historical development of the field, the fundamental physics of radiative surfaces, along with modern measurement methods and equipment.

  10. Lunar radiation environment

    NASA Astrophysics Data System (ADS)

    Schwadron, Nathan; Spence, Harlan; Wilson, Jody

    One of the goals of the CRaTER investigation is to characterize the radiation environment near the Moon in order to enable exploration. The state-of-the-art understanding developed thus far during the LRO mission is documented in a special issue of the Spaceweather Journal entitled “Space Weather: Building the observational foundation to deduce biological effects of space radiation” (Schwadron et al., 2013a). This recently published CRaTER work probes deeper into the physics of the radiation environment at the Moon. It motivates and provides the scientific basis for new investigations in the next phase of the LRO mission. The effects of Galactic Cosmic Rays (GCRs) and Solar Energetic Particles (SEPs) range from chemical modification of the regolith, the generation of a radiation albedo that is increasingly illuminating chemical properties of the regolith, causing charging of the regolith and hazards to human explorers and robotic missions. Low-lunar orbit provides a platform for measuring SEP anisotropy over timescales of 2 hours both parallel and perpendicular to the ecliptic plane, and so far we have observed more than 18 SEP events with time-variable anisotropies during the LRO mission. Albedo proton maps of the Moon from CRaTER indicate that the flux of lunar albedo protons is correlated with elemental abundances at the lunar surface. The yield of albedo protons from the maria is 1% higher than the yield from the highlands, and there are localized peaks with even higher contrast (that may be co-located with peaks in trace elemental abundances as measured by the Lunar Prospector Gamma Ray Spectrometer). The Moon’s radiation environment both charges and affects the chemistry in the Moon’s polar regions, particularly in PSRs. This makes these regions a prime target for new CRaTER observations, since CRaTER measures GCRs and SEPs that penetrate the regolith down to 10s of cm. Thus, we review emerging discoveries from LRO/CRaTER’s remarkable exploration of

  11. Utrecht Radiative Transfer Courses

    NASA Astrophysics Data System (ADS)

    Rutten, R. J.

    2003-01-01

    The Utrecht course ``The Generation and Transport of Radiation'' teaches basic radiative transfer to second-year students. It is a much-expanded version of the first chapter of Rybicki & Lightman's ``Radiative Processes in Astrophysics''. After this course, students understand why intensity is measured per steradian, have an Eddington-Barbier feel for optically thick line formation, and know that scattering upsets LTE. The text is a computer-aided translation by Ruth Peterson of my 1992 Dutch-language course. My aim is to rewrite this course in non-computer English and make it web-available at some time. In the meantime, copies of the Peterson translation are made yearly at Uppsala -- ask them, not me. Eventually it should become a textbook. The Utrecht course ``Radiative Transfer in Stellar Atmospheres'' is a 30-hour course for third-year students. It treats NLTE line formation in plane-parallel stellar atmospheres at a level intermediate between the books by Novotny and Boehm-Vitense, and Mihalas' ``Stellar Atmospheres''. After this course, students appreciate that epsilon is small, that radiation can heat or cool, and that computers have changed the field. This course is web-available since 1995 and is regularly improved -- but remains incomplete. Eventually it should become a textbook. The three Utrecht exercise sets ``Stellar Spectra A: Basic Line Formation'', ``Stellar Spectra B: LTE Line Formation'', and ``Stellar Spectra C: NLTE Line Formation'' are IDL-based computer exercises for first-year, second-year, and third-year students, respectively. They treat spectral classification, Saha-Boltzmann population statistics, the curve of growth, the FAL-C solar atmosphere model, the role of H-minus in the solar continuum, LTE formation of Fraunhofer lines, inversion tactics, the Feautrier method, classical lambda iteration, and ALI computation. The first two sets are web-available since 1998; the third will follow. Acknowledgement. Both courses owe much to previous

  12. Method for microbeam radiation therapy

    DOEpatents

    Slatkin, Daniel N.; Dilmanian, F. Avraham; Spanne, Per O.

    1994-01-01

    A method of performing radiation therapy on a patient, involving exposing a target, usually a tumor, to a therapeutic dose of high energy electromagnetic radiation, preferably X-ray radiation, in the form of at least two non-overlapping microbeams of radiation, each microbeam having a width of less than about 1 millimeter. Target tissue exposed to the microbeams receives a radiation dose during the exposure that exceeds the maximum dose that such tissue can survive. Non-target tissue between the microbeams receives a dose of radiation below the threshold amount of radiation that can be survived by the tissue, and thereby permits the non-target tissue to regenerate. The microbeams may be directed at the target from one direction, or from more than one direction in which case the microbeams overlap within the target tissue enhancing the lethal effect of the irradiation while sparing the surrounding healthy tissue.

  13. Space Radiation Research at NASA

    NASA Technical Reports Server (NTRS)

    Norbury, John

    2016-01-01

    The harmful effects of space radiation on astronauts is one of the most important limiting factors for human exploration of space beyond low Earth orbit, including a journey to Mars. This talk will present an overview of space radiation issues that arise throughout the solar system and will describe research efforts at NASA aimed at studying space radiation effects on astronauts, including the experimental program at the NASA Space Radiation Laboratory at Brookhaven National Laboratory. Recent work on galactic cosmic ray simulation at ground based accelerators will also be presented. The three major sources of space radiation, namely geomagnetically trapped particles, solar particle events and galactic cosmic rays will be discussed as well as recent discoveries of the harmful effects of space radiation on the human body. Some suggestions will also be given for developing a space radiation program in the Republic of Korea.

  14. Head Resistance Due to Radiators

    NASA Technical Reports Server (NTRS)

    Kleinschmidt, R V; Parsons, S R

    1920-01-01

    Part 1 deals with the head resistance of a number of common types of radiator cores at different speeds in free air, as measured in the wind tunnel at the bureau of standards. This work was undertaken to determine the characteristics of various types of radiator cores, and in particular to develop the best type of radiator for airplanes. Some 25 specimens of core were tested, including practically all the general types now in use, except the flat plate type. Part 2 gives the results of wind tunnel tests of resistance on a model fuselage with a nose radiator. Part 3 presents the results of preliminary tests of head resistance of a radiator enclosed in a streamlined casing. Special attention is given to the value of wing radiator and of the radiator located in the open, especially when it is provided with a properly designed streamlined casing.

  15. Ionizing radiation and cancer prevention.

    PubMed Central

    Hoel, D G

    1995-01-01

    Ionizing radiation long has been recognized as a cause of cancer. Among environmental cancer risks, radiation is unique in the variety of organs and tissues that it can affect. Numerous epidemiological studies with good dosimetry provide the basis for cancer risk estimation, including quantitative information derived from observed dose-response relationships. The amount of cancer attributable to ionizing radiation is difficult to estimate, but numbers such as 1 to 3% have been suggested. Some radiation-induced cancers attributable to naturally occurring exposures, such as cosmic and terrestrial radiation, are not preventable. The major natural radiation exposure, radon, can often be reduced, especially in the home, but not entirely eliminated. Medical use of radiation constitutes the other main category of exposure; because of the importance of its benefits to one's health, the appropriate prevention strategy is to simply work to minimize exposures. PMID:8741791

  16. DOE 2011 occupational radiation exposure

    SciTech Connect

    none,

    2012-12-01

    The U.S. Department of Energy (DOE) Office of Analysis within the Office of Health, Safety and Security (HSS) publishes the annual DOE Occupational Radiation Exposure Report to provide an overview of the status of radiation protection practices at DOE (including the National Nuclear Security Administration [NNSA]). The DOE 2011 Occupational Radiation Exposure Report provides an evaluation of DOE-wide performance regarding compliance with Title 10, Code of Federal Regulations (C.F.R.), Part 835, Occupational Radiation Protection dose limits and as low as reasonably achievable (ALARA) process requirements. In addition, the report provides data to DOE organizations responsible for developing policies for protection of individuals from the adverse health effects of radiation. The report provides a summary and an analysis of occupational radiation exposure information from the monitoring of individuals involved in DOE activities. The occupational radiation exposure information is analyzed in terms of aggregate data, dose to individuals, and dose by site over the past five years.

  17. New Approaches to Radiation Protection

    PubMed Central

    Rosen, Eliot M.; Day, Regina; Singh, Vijay K.

    2015-01-01

    Radioprotectors are compounds that protect against radiation injury when given prior to radiation exposure. Mitigators can protect against radiation injury when given after exposure but before symptoms appear. Radioprotectors and mitigators can potentially improve the outcomes of radiotherapy for cancer treatment by allowing higher doses of radiation and/or reduced damage to normal tissues. Such compounds can also potentially counteract the effects of accidental exposure to radiation or deliberate exposure (e.g., nuclear reactor meltdown, dirty bomb, or nuclear bomb explosion); hence they are called radiation countermeasures. Here, we will review the general principles of radiation injury and protection and describe selected examples of radioprotectors/mitigators ranging from small-molecules to proteins to cell-based treatments. We will emphasize agents that are in more advanced stages of development. PMID:25653923

  18. Chapter 1: Direct Normal Radiation

    SciTech Connect

    Myer, Daryl R.

    2016-04-15

    This chapter addresses the quantitative and qualitative aspects of the solar resource, the direct solar radiation. It discusses the total or integrated broadband direct beam extraterrestrial radiation (ETR). This total integrated irradiance is comprised of photons of electromagnetic radiation. The chapter also discusses the impact of the atmosphere and its effect upon the direct normal irradiance (DNI) beam radiation. The gases and particulates present in the atmosphere traversed by the direct beam reflect, absorb, and scatter differing spectral regions and proportions of the direct beam, and act as a variable filter. Knowledge of the available broadband DNI beam radiation resource data is essential in designing a concentrating photovoltaic (CPV) system. Spectral variations in the DNI beam radiation affect the performance of a CPV system depending on the solar cell technology used. The chapter describes propagation and scattering processes of circumsolar radiation (CSR), which includes the Mie scattering from large particles.

  19. Method for microbeam radiation therapy

    DOEpatents

    Slatkin, D.N.; Dilmanian, F.A.; Spanne, P.O.

    1994-08-16

    A method is disclosed of performing radiation therapy on a patient, involving exposing a target, usually a tumor, to a therapeutic dose of high energy electromagnetic radiation, preferably X-ray radiation. The dose is in the form of at least two non-overlapping microbeams of radiation, each microbeam having a width of less than about 1 millimeter. Target tissue exposed to the microbeams receives a radiation dose during the exposure that exceeds the maximum dose that such tissue can survive. Non-target tissue between the microbeams receives a dose of radiation below the threshold amount of radiation that can be survived by the tissue, and thereby permits the non-target tissue to regenerate. The microbeams may be directed at the target from one direction, or from more than one direction in which case the microbeams overlap within the target tissue enhancing the lethal effect of the irradiation while sparing the surrounding healthy tissue. No Drawings

  20. Changing aspects of radiation enteropathy

    SciTech Connect

    Morgenstern, L.; Hart, M.; Lugo, D.; Friedman, N.B.

    1985-11-01

    Fifty-two patients with radiation enteropathy secondary to radiation for abdominal or pelvic malignant neoplasms are described. This series (1977 to 1984) is compared with a series of 50 patients from the same institution over an earlier period (1961 to 1977). Intestinal obstruction was the principal complication in both series; 96% of the patients underwent either intestinal resection or anastomotic bypass of the affected segment. Changes that have occurred since the last report are as follows: changes in source of radiation energy (linear accelerator); less evidence of mucosal damage; increased serosal reaction (''serosal peel''); and increased use of elemental diets, parenteral nutrition, and long intestinal tubes in surgical management. Since postoperative radiation injury occurs most frequently in the pelvis, new developments for the exclusion of small bowel from the pelvis during radiation are reviewed. Changes in fractionation of radiation dosage should also be considered in patients with enteric symptoms during radiation therapy.

  1. DOE 2012 occupational radiation exposure

    SciTech Connect

    none,

    2013-10-01

    The U.S. Department of Energy (DOE) Office of Analysis within the Office of Health, Safety and Security (HSS) publishes the annual DOE Occupational Radiation Exposure Report to provide an overview of the status of radiation protection practices at DOE (including the National Nuclear Security Administration [NNSA]). The DOE 2012 Occupational Radiation Exposure Report provides an evaluation of DOE-wide performance regarding compliance with Title 10, Code of Federal Regulations (C.F.R.), Part 835, Occupational Radiation Protection dose limits and as low as reasonably achievable (ALARA) process requirements. In addition, the report provides data to DOE organizations responsible for developing policies for protection of individuals from the adverse health effects of radiation. The report provides a summary and an analysis of occupational radiation exposure information from the monitoring of individuals involved in DOE activities. Over the past 5-year period, the occupational radiation exposure information is analyzed in terms of aggregate data, dose to individuals, and dose by site.

  2. Influence of Extraterrestrial Radiation on Radiation Portal Monitors

    SciTech Connect

    Keller, Paul E.; Kouzes, Richard T.

    2009-06-01

    Cosmic radiation and solar flares can be a major source of background radiation at the Earth’s surface. This paper examines the relationship between extraterrestrial radiation and the detectable background in radiation portal monitors used for homeland security applications. Background radiation data from 13 radiation portal monitor facilities are examined and compared against external sources of data related to extraterrestrial radiation, including measurements at neutron monitors located at 53 cosmic-ray observatories around the Earth, four polar orbiting satellites, three geostationary satellites, ground-based geomagnetic field data from observatories around the Earth, a solar magnetic index, solar radio flux data, and sunspot activity data. Four-years (January 2003 through December 2006) of data are used in this study, which include the latter part of Solar Cycle 23 as solar activity was on the decline. The analysis shows a significant relationship between some extraterrestrial radiation and the background detected in the radiation portal monitors. A demonstrable decline is shown in the average gamma ray and neutron background at the radiation portal monitors as solar activity declined over the period of the study.

  3. Radiation Safety System for Stanford Synchrotron Radiation Laboratory

    SciTech Connect

    Liu, J

    2004-03-12

    Radiation Safety System (RSS) at the Stanford Synchrotron Radiation Laboratory is summarized and reviewed. The RSS, which is designed to protect people from prompt radiation hazards from accelerator operation, consists of the Access Control System (ACS) and the Beam Containment System (BCS). The ACS prevents people from being exposed to the lethal radiation level inside the shielding housing (called a PPS area at SLAC). The ACS for a PPS area consists of the shielding housing, beam inhibiting devices, and a standard entry module at each entrance. The BCS protects people from the prompt radiation hazards outside a PPS area under both normal and abnormal beam loss situations. The BCS consists of the active power (current/energy) limiting devices, beam stoppers, shielding, and an active radiation monitor system. The policies and practices in setting up the RSS at SLAC are illustrated.

  4. Structure in Radiating Shocks

    NASA Astrophysics Data System (ADS)

    Doss, Forrest

    2010-11-01

    The basic radiative shock experiment is a shock launched into a gas of high-atomic-number material at high velocities, which fulfills the conditions for radiative losses to collapse the post-shock material to over 20 times the initial gas density. This has been accomplished using the OMEGA Laser Facility by illuminating a Be ablator for 1 ns with a total of 4 kJ, launching the requisite shock, faster than 100 km/sec, into a polyimide shock tube filled with Xe. The experiments have lateral dimensions of 600 μm and axial dimensions of 2-3 mm, and are diagnosed by x-ray backlighting. Repeatable structure beyond the one-dimensional picture of a shock as a planar discontinuity was discovered in the experimental data. One form this took was that of radial boundary effects near the tube walls, extended approximately seventy microns into the system. The cause of this effect - low density wall material which is heated by radiation transport ahead of the shock, launching a new converging shock ahead of the main shock - is apparently unique to high-energy-density experiments. Another form of structure is the appearance of small-scale perturbations in the post-shock layer, modulating the shock and material interfaces and creating regions of enhanced and diminished aerial density within the layer. The authors have applied an instability theory, a variation of the Vishniac instability of decelerating shocks, to describe the growth of these perturbations. We have also applied Bayesian statistical methods to better understand the uncertainties associated with measuring shocked layer thickness in the presence of tilt. Collaborators: R. P. Drake, H. F. Robey, C. C. Kuranz, C. M. Huntington, M. J. Grosskopf, D. C. Marion.

  5. Analysis of Contribution from Edge Radiation to Optical Diffraction Radiation

    SciTech Connect

    C. Liu, P. Evtushenko, A. Freyberger, C. Liu, A.H. Lumpkin

    2009-05-01

    Beam size measurement with near-field optical diffraction radiation (ODR) has been carried out successfully at CEBAF. The ODR station is installed on the Hall-A beam line after eight bending magnets. The ODR images were affected by an unexpected radiation. Some calculations for analyzing the source of the radiation will be presented. Furthermore, two schemes will be proposed to alleviate the contamination.

  6. Cosmic Background Radiation

    NASA Astrophysics Data System (ADS)

    Sidharth, B. G.; Valluri, S. R.

    2015-08-01

    It is shown that a collection of photons with nearly the same frequency exhibits a "condensation" type of phenomenon corresponding to a peak intensity. The observed cosmic background radiation can be explained from this standpoint. We have obtained analogous results by extremization of the occupation number for photons with the use of the Lambert W function. Some of the interesting applications of this function are briefly discussed in the context of graphene which exhibits an interesting two dimensional structure with several characteristic properties and diverse practical applications.

  7. Radiation Safety Committee report

    SciTech Connect

    Almond, P.

    1986-01-01

    There are three groups of people concerned with the radiation safety and health hazards associated with californium. These three groups are the general public, hospital personnel who are involved in californium treatments, and the patients themselves. There is also a subgroup in groups one and two, and possibly group three, although very unlikely, and that is the unborn child or fetus. This subgroup is applicable when the mother is in the very early stages of pregnancy, at which time the mother does not know that she is pregnant. The author discusses the concerns for the three groups in detail.

  8. Aerial radiation surveys

    SciTech Connect

    Jobst, J.

    1980-01-01

    A recent aerial radiation survey of the surroundings of the Vitro mill in Salt Lake City shows that uranium mill tailings have been removed to many locations outside their original boundary. To date, 52 remote sites have been discovered within a 100 square kilometer aerial survey perimeter surrounding the mill; 9 of these were discovered with the recent aerial survey map. Five additional sites, also discovered by aerial survey, contained uranium ore, milling equipment, or radioactive slag. Because of the success of this survey, plans are being made to extend the aerial survey program to other parts of the Salt Lake valley where diversions of Vitro tailings are also known to exist.

  9. Radiation Belt Dynamics

    DTIC Science & Technology

    2015-12-27

    is unlimited. 15 DISTRIBUTION LIST DTIC/OCP 8725 John J. Kingman Rd, Suite 0944 Ft Belvoir, VA 22060-6218 1 cy AFRL /RVIL Kirtland AFB, NM 87117... AFRL -RV-PS- AFRL -RV-PS- TR-2016-0007 TR-2016-0007 RADIATION BELT DYNAMICS Jay M. Albert, et al. 27 December 2015 Final Report APPROVED FOR... KIRTLAND AIR FORCE BASE, NM 87117-5776 DTIC COPY NOTICE AND SIGNATURE PAGE Using Government drawings, specifications, or other data included in this

  10. Radiation imaging apparatus

    DOEpatents

    Anger, H.O.; Martin, D.C.; Lampton, M.L.

    1983-07-26

    A radiation imaging system using a charge multiplier and a position sensitive anode in the form of periodically arranged sets of interconnected anode regions for detecting the position of the centroid of a charge cloud arriving thereat from the charge multiplier. Various forms of improved position sensitive anodes having single plane electrode connections are disclosed. Various analog and digital signal processing systems are disclosed, including systems which use the fast response of microchannel plates, anodes and preamps to perform scintillation pulse height analysis digitally. 15 figs.

  11. Radiation imaging apparatus

    DOEpatents

    Anger, Hal O.; Martin, Donn C.; Lampton, Michael L.

    1983-01-01

    A radiation imaging system using a charge multiplier and a position sensitive anode in the form of periodically arranged sets of interconnected anode regions for detecting the position of the centroid of a charge cloud arriving thereat from the charge multiplier. Various forms of improved position sensitive anodes having single plane electrode connections are disclosed. Various analog and digital signal processing systems are disclosed, including systems which use the fast response of microchannel plates, anodes and preamps to perform scintillation pulse height analysis digitally.

  12. Protection from Space Radiation

    NASA Technical Reports Server (NTRS)

    Tripathi, R. K.; Wilson, J. W.; Shinn, J. L.; Singleterry, R. C.; Clowdsley, M. S.; Cucinotta, F. A.; Badhwar, G. D.; Kim, M. Y.; Badavi, F. F.; Heinbockel, J. H.

    2000-01-01

    The exposures anticipated for our astronauts in the anticipated Human Exploration and Development of Space (HEDS) will be significantly higher (both annual and carrier) than any other occupational group. In addition, the exposures in deep space result largely from the Galactic Cosmic Rays (GCR) for which there is as yet little experience. Some evidence exists indicating that conventional linear energy transfer (LET) defined protection quantities (quality factors) may not be appropriate [1,2]. The purpose of this presentation is to evaluate our current understanding of radiation protection with laboratory and flight experimental data and to discuss recent improvements in interaction models and transport methods.

  13. The space radiation environment

    SciTech Connect

    Robbins, D.E.

    1997-04-30

    There are three primary sources of space radiation: galactic cosmic rays (GCR), trapped belt radiation, and solar particle events (SPE). All are composed of ions, the nuclei of atoms. Their energies range from a few MeV u{sup -1} to over a GeV u{sup -1}. These ions can fragment when they interact with spacecraft materials and produce energetic neutrons and ions of lower atomic mass. Absorbed dose rates inside a typical spacecraft (like the Space Shuttle) in a low inclination (28.5 degrees) orbit range between 0.05 and 2 mGy d{sup -1} depending on the altitude and flight inclination (angle of orbit with the equator). The quality factor of radiation in orbit depends on the relative contributions of trapped belt radiation and GCR, and the dose rate varies both with orbital altitude and inclination. The corresponding equivalent dose rate ranges between 0.1 and 4 mSv d{sup -1}. In high inclination orbits, like that of the Mir Space Station and as is planned for the International Space Station, blood-forming organ (BFO) equivalent dose rates as high as 1.5 mSv d{sup -1}. Thus, on a 1 y mission, a crew member could obtain a total dose of 0.55 Sv. Maximum equivalent dose rates measured in high altitude passes through the South Atlantic Anomaly (SAA) were 10 mSv h{sup -1}. For an interplanetary space mission (e.g., to Mars) annual doses from GCR alone range between 150 mSv y{sup -1} at solar maximum and 580 mSv y{sup -1} at solar minimum. Large SPE, like the October 1989 series, are more apt to occur in the years around solar maximum. In free space, such an event could contribute another 300 mSv, assuming that a warning system and safe haven can be effectively used with operational procedures to minimize crew exposures. Thus, the total dose for a 3 y mission to Mars could exceed 2 Sv.

  14. Iron, radiation, and cancer.

    PubMed Central

    Stevens, R G; Kalkwarf, D R

    1990-01-01

    Increased iron content of cells and tissue may increase the risk of cancer. In particular, high available iron status may increase the risk of a radiation-induced cancer. There are two possible mechanisms for this effect: iron can catalyze the production of oxygen radicals, and it may be a limiting nutrient to the growth and development of a transformed cell in vivo. Given the high available iron content of the western diet and the fact that the world is changing to the western model, it is important to determine if high iron increases the risk of cancer. PMID:2269234

  15. LDEF satellite radiation study

    NASA Technical Reports Server (NTRS)

    Armstrong, T. W.; Colborn, B. L.

    1994-01-01

    Some early results are summarized from a program under way to utilize LDEF satellite data for evaluating and improving current models of the space radiation environment in low earth orbit. Reported here are predictions and comparisons with some of the LDEF dose and induced radioactivity data, which are used to check the accuracy of current models describing the magnitude and directionality of the trapped proton environment. Preliminary findings are that the environment models underestimate both dose and activation from trapped protons by a factor of about two, and the observed anisotropy is higher than predicted.

  16. Protection from space radiation

    SciTech Connect

    Tripathi, R.K.; Wilson, J.W.; Shinn, J.L.

    2000-07-01

    The exposures anticipated for astronauts in the anticipated human exploration and development of space will be significantly higher (both annual and carrier) than for any other occupational group. In addition, the exposures in deep space result largely from galactic cosmic rays for which there is as yet little experience. Some evidence exists indicating that conventional linear energy transfer defined protection quantities (quality factors) may not be appropriate. The authors evaluate their current understanding of radiation protection with laboratory and flight experimental data and discuss recent improvements in interaction models and transport methods.

  17. Virtual Gamma Ray Radiation Sources through Neutron Radiative Capture

    SciTech Connect

    Scott Wilde, Raymond Keegan

    2008-07-01

    The countrate response of a gamma spectrometry system from a neutron radiation source behind a plane of moderating material doped with a nuclide of a large radiative neutron capture cross-section exhibits a countrate response analogous to a gamma radiation source at the same position from the detector. Using a planar, surface area of the neutron moderating material exposed to the neutron radiation produces a larger area under the prompt gamma ray peak in the detector than a smaller area of dimensions relative to the active volume of the gamma detection system.

  18. METHODOLOGICAL NOTES: Radiation damping forces and radiation from charged particles

    NASA Astrophysics Data System (ADS)

    Klepikov, N. P.

    1985-06-01

    A review of the literature on the radiation reaction force on a charged particle shows that the expression given for this force obtained by Lorentz, Abraham, and Dirac is in physically reasonable agreement with the radiation of energy, momentum, and angular momentum, and is successfully used in investigating the motion of particles in a field. A selection of physical solutions by the methods presented herein guarantees that the conservation laws are satisfied. In the first approximation, which is the only one utilized in the majority of physical situations, radiation damping does not depend on assumptions concerning the structure of the charge of the particle. A theory is presented of the losses of energy, momentum and angular momentum by a system of charged particles in the course of their moving together taking into account the external field, the radiation damping forces, and the retarded Lienard-Wiechert forces. Formulas are given for the spectral and angular distribution of the radiation from a system of particles. The concept of a center of a system of events with relativistic particles is utilized in constructing a system of equations for finding the angular momenta of the electromagnetic waves radiated by particles of the system. The angular distribution and the total intensity of the radiation from a system of particles at an arbitrary instant of time is obtained. Using the example of the joint synchrotron radiation from two particles the consistency of all three approaches to the radiation from a system of particles is demonstrated.

  19. Evidence-based recommendations for optimal dietary protein intake in older people: a position paper from the PROT-AGE Study Group.

    PubMed

    Bauer, Jürgen; Biolo, Gianni; Cederholm, Tommy; Cesari, Matteo; Cruz-Jentoft, Alfonso J; Morley, John E; Phillips, Stuart; Sieber, Cornel; Stehle, Peter; Teta, Daniel; Visvanathan, Renuka; Volpi, Elena; Boirie, Yves

    2013-08-01

    New evidence shows that older adults need more dietary protein than do younger adults to support good health, promote recovery from illness, and maintain functionality. Older people need to make up for age-related changes in protein metabolism, such as high splanchnic extraction and declining anabolic responses to ingested protein. They also need more protein to offset inflammatory and catabolic conditions associated with chronic and acute diseases that occur commonly with aging. With the goal of developing updated, evidence-based recommendations for optimal protein intake by older people, the European Union Geriatric Medicine Society (EUGMS), in cooperation with other scientific organizations, appointed an international study group to review dietary protein needs with aging (PROT-AGE Study Group). To help older people (>65 years) maintain and regain lean body mass and function, the PROT-AGE study group recommends average daily intake at least in the range of 1.0 to 1.2 g protein per kilogram of body weight per day. Both endurance- and resistance-type exercises are recommended at individualized levels that are safe and tolerated, and higher protein intake (ie, ≥ 1.2 g/kg body weight/d) is advised for those who are exercising and otherwise active. Most older adults who have acute or chronic diseases need even more dietary protein (ie, 1.2-1.5 g/kg body weight/d). Older people with severe kidney disease (ie, estimated GFR <30 mL/min/1.73 m(2)), but who are not on dialysis, are an exception to this rule; these individuals may need to limit protein intake. Protein quality, timing of ingestion, and intake of other nutritional supplements may be relevant, but evidence is not yet sufficient to support specific recommendations. Older people are vulnerable to losses in physical function capacity, and such losses predict loss of independence, falls, and even mortality. Thus, future studies aimed at pinpointing optimal protein intake in specific populations of older people

  20. Diverse incidences of individual oligopeptides (dipeptidic to hexapeptidic) in proteins of human, bakers' yeast, and Escherichia coli origin registered in the Swiss-Prot data base.

    PubMed Central

    Doi, H; Kitajima, M; Watanabe, I; Kikuchi, Y; Matsuzawa, F; Aikawa, S; Takiguchi, K; Ohno, S

    1995-01-01

    Oligopeptidic permutations of the 20 amino acid residues give rise to proteins of diverse functions. Our long-term goal is to produce a lexicon of oligopeptides, classifying them into at least five categories: (i) ubiquitous, (ii) function specific, (iii) group specific, (iv) species specific, and (v) nonexistent. To begin with, we report on the varying frequencies of individual oligopeptides (dipeptidic to hexapeptidic in length) found among 2862 human proteins, 1942 Saccharomyces cerevisiae proteins, and 2672 Escherichia coli proteins registered in the Swiss-Prot data base (version 29.0, released in June 1994). At all lengths (dipeptides to hexapeptides), homooligopeptides were very prominent among the most frequently occurring varieties in proteins of human and bakers' yeast origins. However, this was not the case with E. coli. While all of the expected 20(3) varieties of tripeptides were found among human proteins, three tripeptides (Cys-Cys-Trp, Trp-Trp-Cys, and Trp-Trp-His) were missing from the bakers' yeast proteins. Three tripeptides (Cys-Ile-Trp, Cys-Met-Tyr, and Cys-Trp-Trp) were also absent from E. coli proteins. Inasmuch as the Swiss-Prot data base already contained 67% of the expected total of 4000 E. coli proteins, it is virtually certain that 96,000 varieties of hexapeptides containing at least one or another of the three missing tripeptides noted above shall be nonexistent in E. coli. Furthermore, the observation of missing tripeptides in the bakers' yeast proteins suggests that nonexistent hexapeptides shall be highly phylum specific. Because of the sample size, only a small fraction of the 20(6) varieties of hexapeptides were expected to be encountered in the present survey. Indeed, only 1.2-1.5% of the possible hexapeptides were found, and the average copy number of observed hexapeptides varied between 1.06 and 1.25. Nevertheless, 33 varieties of hexapeptides occurred in 102-169 copies among human proteins. Furthermore, 15 of the 33 varieties